WorldWideScience

Sample records for tm vrdleb 40-42

  1. Passive Q-switching of femtosecond-laser-written Tm:KLu(WO4)2 waveguide lasers by graphene and MoS2 saturable absorbers

    Science.gov (United States)

    Kifle, Esrom; Mateos, Xavier; Vázquez de Aldana, Javier Rodríguez; Ródenas, Airan; Loiko, Pavel; Zakharov, Viktor; Veniaminov, Andrey; Yu, Haohai; Zhang, Huaijin; Chen, Yanxue; Aguiló, Magdalena; Díaz, Francesc; Griebner, Uwe; Petrov, Valentin

    2018-02-01

    A buried depressed-index channel waveguide with a circular cladding and a core diameter of 40 μm is fabricated in a bulk monoclinic 3 at.% Tm:KLu(WO4)2 crystal by femtosecond direct laser writing. In the continuous-wave regime, the Tm waveguide laser generates 210 mW at 1849.6 nm with a slope efficiency η of 40.8%. Passively Q-switched operation is achieved by inserting transmission-type 2D saturable absorbers (SAs) based on few-layer graphene and MoS2. Using the graphene-SA, a maximum average output power of 25 mW is generated at 1844.8 nm. The pulse characteristics (duration/energy) are 88 ns/18 nJ at a repetition rate of 1.39 MHz.

  2. CW lasing of Ho in KLu(WO4)2 in-band pumped by a diode-pumped Tm:KLu(WO4)2 laser.

    Science.gov (United States)

    Mateos, Xavier; Jambunathan, Venkatesan; Pujol, Maria Cinta; Carvajal, Joan Josep; Díaz, Francesc; Aguiló, Magdalena; Griebner, Uwe; Petrov, Valentin

    2010-09-27

    We demonstrate continuous wave (CW) room temperature laser operation of the monoclinic Ho(3+)-doped KLu(WO(4))(2) crystal using a diode-pumped Tm(3+):KLu(WO(4))(2) laser for in-band pumping. The slope efficiency achieved amounts to ~55% with respect to the absorbed power and the maximum output power of 648 mW is generated at 2078 nm.

  3. Growth and spectroscopic properties of Tm3+:NaBi(MoO4)2 single crystal

    Science.gov (United States)

    Gusakova, N. V.; Mudryi, A. V.; Demesh, M. P.; Yasukevich, A. S.; Pavlyuk, A. A.; Kornienko, A. A.; Dunina, E. B.; Khodasevich, I. A.; Orlovich, V. A.; Kuleshov, N. V.

    2018-06-01

    In this work we report the spectroscopic properties of Tm3+:NaBi(MoO4)2 crystals with the dopant concentrations of 0.7 at.% and 3 at.%. The energy levels of the Tm3+ in the NaBi(MoO4)2 host were determined from polarized optical absorption and photoluminescence spectra measured at 77.4 K. Radiative properties of the crystals were calculated in context of Judd-Ofelt theory. Raman spectra of the crystal were studied. The concentration dependences of emission decay times of 3H4 and 3F4 levels were analyzed. The potential of the crystal for building tunable and ultrafast pulse lasers is shown on the base of cross sections and gain coefficient in the range of 1.9 μm.

  4. 40 CFR 194.42 - Monitoring.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Monitoring. 194.42 Section 194.42... § 194.42 Monitoring. (a) The Department shall conduct an analysis of the effects of disposal system...-closure and post-closure monitoring required pursuant to paragraphs (c) and (d) of this section. The...

  5. Passive mode locking of a Tm,Ho:KY(WO4)2 laser around 2 microm.

    Science.gov (United States)

    Lagatsky, A A; Fusari, F; Calvez, S; Gupta, J A; Kisel, V E; Kuleshov, N V; Brown, C T A; Dawson, M D; Sibbett, W

    2009-09-01

    We report the first demonstration, to our knowledge, of passive mode locking in a Tm(3+), Ho(3+)-codoped KY(WO(4))(2) laser operating in the 2000-2060 nm spectral region. An InGaAsSb-based quantum well semiconductor saturable absorber mirror is used for the initiation and stabilization of the ultrashort pulse generation. Pulses as short as 3.3 ps were generated at 2057 nm with average output powers up to 315 mW at a pulse repetition frequency of 132 MHz for 1.15 W of absorbed pump power at 802 nm from a Ti:sapphire laser.

  6. tmRDB (tmRNA database)

    DEFF Research Database (Denmark)

    Zwieb, Christian; Gorodkin, Jan; Knudsen, Bjarne

    2003-01-01

    Maintained at the University of Texas Health Science Center at Tyler, Texas, the tmRNA database (tmRDB) is accessible at the URL http://psyche.uthct.edu/dbs/tmRDB/tmRDB.html with mirror sites located at Auburn University, Auburn, Alabama (http://www.ag.auburn.edu/mirror/tmRDB/) and the Bioinforma......Maintained at the University of Texas Health Science Center at Tyler, Texas, the tmRNA database (tmRDB) is accessible at the URL http://psyche.uthct.edu/dbs/tmRDB/tmRDB.html with mirror sites located at Auburn University, Auburn, Alabama (http......://www.ag.auburn.edu/mirror/tmRDB/) and the Bioinformatics Research Center, Aarhus, Denmark (http://www.bioinf.au.dk/tmRDB/). The tmRDB collects and distributes information relevant to the study of tmRNA. In trans-translation, this molecule combines properties of tRNA and mRNA and binds several proteins to form the tmRNP. Related RNPs are likely...

  7. 40 CFR 230.42 - Mud flats.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Mud flats. 230.42 Section 230.42... Aquatic Sites § 230.42 Mud flats. (a) Mud flats are broad flat areas along the sea coast and in coastal rivers to the head of tidal influence and in inland lakes, ponds, and riverine systems. When mud flats...

  8. Energy transfer processes in Yb{sup 3+}-Tm{sup 3+} co-doped sodium alumino-phosphate glasses with improved 1.8 {mu}m emission

    Energy Technology Data Exchange (ETDEWEB)

    Camargo, Andrea S S de; Terra, Idelma A A; Nunes, Luiz Antonio de O; Li, M Siu [Instituto de Fisica de Sao Carlos, Universidade de Sao Paulo, 13560-970, Sao Carlos-SP (Brazil)], E-mail: andreasc@ifsc.usp.br

    2008-06-25

    Sodium alumino-phosphate glasses co-doped with Yb{sup 3+} and Tm{sup 3+} ions have been prepared with notably low OH{sup -} content, and characterized from the viewpoint of their spectroscopic properties. In these glasses, Yb{sup 3+} acts as an efficient sensitizer of excitation energy at 0.98 {mu}m-which can be provided by high power and low cost diode lasers, and subsequently undergoes non-resonant energy transfer to Tm{sup 3+} ions ({sup 2}F{sub 5/2}, {sup 3}H{sub 6} {yields} {sup 2}F{sub 7/2}, {sup 3}H{sub 5}). Through this process, the emitting level {sup 3}F{sub 4} is rapidly populated, generating improved emission at 1.8 {mu}m ({sup 3}F{sub 4} {yields} {sup 3}H{sub 6}). In order to guarantee the efficiency of such favorable energy transfer, energy losses via multiphonon decay, Yb-Yb radiative trapping, and non-radiative transfer to OH{sup -} groups were evaluated, and minimized when possible. The dipole-dipole energy transfer microscopic parameters corresponding to Yb{sup 3+} {yields} Tm{sup 3+}, Yb{sup 3+} {yields} Yb{sup 3+} and Tm{sup 3+} {yields} Tm{sup 3+} transfers, calculated by the Foerster-Dexter model, are C{sub Yb-Tm} = 2.9 x 10{sup -40} cm{sup 6} s{sup -1}, C{sub Yb-Yb} = 42 x 10{sup -40} cm{sup 6} s{sup -1} and C{sub Tm-Tm} = 43 x 10{sup -40} cm{sup 6} s{sup -1}, respectively.

  9. Structural, Morphological, Vibrational, and Photoluminescence Study of Sol-Gel-Synthesized Tm3+:NaGd(WO4)2 Blue Phosphors

    Science.gov (United States)

    Durairajan, A.; Thangaraju, D.; Valente, M.; Moorthy Babu, S.

    2015-11-01

    The photoluminescence properties of sol-gel-derived NaGd1- x Tm x (WO4)2 sub-micron powders were studied. Formation of a crystalline material with a tetragonal structure and the I41/a space group was confirmed by powder x-ray diffraction measurements. The surface morphology and size distribution of the powders were investigated by scanning electron microscopy. Double tungstate formation was confirmed by Fourier-transform infrared and Raman spectroscopy and the corresponding vibrations were also assigned. A broad charge-transfer band (CTB) and intra-configurational 4f-4f transitions in the excitation spectra are discussed. Strong blue emission was observed at 455 nm (1D2 → 3F4) for both CTB and intra-configurational 4f-4f excitation bands, and strong emission as a result of intra-configurational 4f-4f excitation only was also observed. The concentration dependence of emission was studied, and emission was found to be maximum for x = 0.05. The corresponding critical distance was also determined and a mechanism is proposed for energy transfer by Tm3+ ions in the NaGd(WO4)2 matrix. The Commission International de l'Eclairage (CIE) coordinates were calculated and fell in the blue region of the CIE diagram. The coordinates of the blue intensity maximum were also matched with European Broadcasting Union standard values.

  10. Comparative study of crystallographic, spectroscopic, and laser properties of Tm3+ in NaT(WO4)2 (T=La, Gd, Y, and Lu) disordered single crystals

    Science.gov (United States)

    Cano-Torres, J. M.; Rico, M.; Han, X.; Serrano, M. D.; Cascales, C.; Zaldo, C.; Petrov, V.; Griebner, U.; Mateos, X.; Koopmann, P.; Kränkel, C.

    2011-11-01

    Tetragonal double tungstate single crystals with formula NaT(WO4)2 have been grown by the Czochralski (T = Gd, La, Y) or by the top-seeded solution growth (T = Lu) methods with Tm concentration between 8 × 1018 and 7.85 × 1020 cm-3. The spectroscopic properties of Tm3+ in these crystals are related with the peculiarities of their I4¯ crystalline structure. Sixty-five percent of La ions in NaLa(WO4)2 are in the 2d site, while in the other crystal hosts, the lanthanide occupies preferentially the 2b site (59% in T = Gd, 74% in T = Y, and 58% in T = Lu). As a consequence, the linewidths of spectral bands associated with the electronic transitions are significantly narrower in NaLa(WO4)2 than in the rest of the isostructural crystals considered. Polarized spectroscopic measurements at 5 K and at higher temperatures, along with energy level simulation of the 4f12 configuration using a single-electron Hamiltonian, including free-ion and crystal field interactions, allowed us to determine the irreducible representation and energy of Stark levels up to the 3P0 multiplet and thus to obtain realistic partition functions (Z) used for emission cross-section calculations. In particular, for the 3F4(u) → 3H6(l) laser transition at λ ≈ 2 μm, this provides: Zl/Zu = 1.436 (T = Gd), 1.464 (T = La), 1.448 (T = Y), and 1.471 (T = Lu). Radiative lifetimes calculated by the Judd-Ofelt and Füchtbauer-Ladenburg methods are in agreement and decrease in the following order T = Gd, La, Y, and Lu, however, nonradiative losses are stronger for T = Gd and La crystals; therefore, experimental lifetimes of 1D2, 1G4, 3H4, and 3F4 Tm3+ multiplets do not change too much with crystal host. For 4.68 at.% Tm:NaY(WO4)2 crystal continuous-wave laser operation is obtained with ≈42% of slope efficiency and a record (for this crystal class) tuning capability of λ = 1847-2069 nm. The broad bandwidths, ΔλFWHM > 20 nm, of the free-running laser emission are promising for ultrafast (fs) mode

  11. 40 CFR 610.42 - Fuel economy measurement.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 29 2010-07-01 2010-07-01 false Fuel economy measurement. 610.42... ECONOMY RETROFIT DEVICES Test Procedures and Evaluation Criteria General Vehicle Test Procedures § 610.42 Fuel economy measurement. (a) Fuel consumption will be measured by: (1) The carbon balance method, or...

  12. The role of stereotactic 11G vacuum biopsy for clarification of BI-RADS{sup TM} IV findings in mammography; Wertigkeit der stereotaktischen 11 G-Vakuumbiopsie zur Abklaerung von Befunden der Kategorie BI-RADS{sup TM} IV in der Mammographie

    Energy Technology Data Exchange (ETDEWEB)

    Diebold, T.; Jacobi, V.; Ballenberger, S.; Hochmuth, K.; Balzer, J.O.; Vogl, T.J. [Inst. fuer Diagnostische und Interventionelle Radiologie, Klinikum der J.W.G.-Univ. Frankfurt/Main (Germany); Krapfl, E.; Minckwitz, G. v.; Solbach, C.; Kaufmann, M. [Klinik fuer Gynaekologie und Geburtshilfe, Klinikum der J.W.G.-Univ. Frankfurt/Main (Germany); Fellbaum, M. [Senckenbergisches Inst. fuer Pathologie, Klinikum der J.W.G.-Univ. Frankfurt/Main (Germany)

    2003-04-01

    Purpose: To evaluate the potential of stereotactic vacuum breast biopsy in the histologic evaluation of suspicious mammographic findings (BI-RADS{sup TM} IV). Materials und Methods: In 221 patients with 227 probable mammographic lesions categorized as (BI-RADS{sup TM}-IV), stereotactic biopsies were performed with an 11-gauge vacuum-assisted biopsy device (Mammotome). The evaluation included the histology of the specimens obtained with the Mammotome or with surgery, the time for the biopsy, the amount of bleeding, number of rotations and procured specimens, the extent of the resection and the complications. Results: The biopsies were technically successful in 214 of the 227 probable mammographic lesions, with 176 lesions mostly resected and 34 lesions removed more than 50%. No representative tissue was obtained from 4 lesions. All biopsies were performed without any clinically relevant complications and terminated after adequate material was obtained (Oe 28 specimens, 2.58 rotations). The mean time needed for performing the biopsy was 40.2 minutes. The histologic findings were DCIS (42 lesions), ADH (7 lesions), LCIS (3 lesions), ID-Ca (14 lesions), IL-Ca (3 lesions), and IDL-Ca (1 lesion). In 28 of 42 lesions with the initial DCIS histology, the surgical histology was also DCIS (n=28) or no residual tumor (n=10). In 4 lesions with an initial DCIS-histology, the surgical histology was invasive ductal cancer (9.5%). The late follow-up examinations (up to 3 years) did not find any evidence of a false negative biopsy. Conclusion: Stereotactic vacuum breast biopsy ideally complements existing breast biopsy methods. The method is minimal invasive with a low rate of mostly minor complications. (orig.) [German] Ziel: Evaluierung der Wertigkeit der stereotaktischen Vakuumbiopsie zur Abklaerung von Befunden der Kategorie BI-RADS{sup TM} IV in der Mammographie. Material und Methode: Bei 221 Patientinnen mit 227 mammographischen Laesionen der BI-RADS{sup TM}-Kategorie IV

  13. 42 CFR 414.40 - Coding and ancillary policies.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 3 2010-10-01 2010-10-01 false Coding and ancillary policies. 414.40 Section 414.40 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES... Practitioners § 414.40 Coding and ancillary policies. (a) General rule. CMS establishes uniform national...

  14. 40 CFR 141.42 - Special monitoring for corrosivity characteristics.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 22 2010-07-01 2010-07-01 false Special monitoring for corrosivity characteristics. 141.42 Section 141.42 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER... Regulations and Prohibition on Lead Use § 141.42 Special monitoring for corrosivity characteristics. (a)-(c...

  15. 40 CFR 68.42 - Five-year accident history.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 15 2010-07-01 2010-07-01 false Five-year accident history. 68.42... (CONTINUED) CHEMICAL ACCIDENT PREVENTION PROVISIONS Hazard Assessment § 68.42 Five-year accident history. (a) The owner or operator shall include in the five-year accident history all accidental releases from...

  16. Gating function of isoleucine-116 in TM-3 (position III:16/3.40) for the activity state of the CC-chemokine receptor 5 (CCR5)

    DEFF Research Database (Denmark)

    Steen, A; Sparre-Ulrich, A H; Thiele, Stefanie

    2014-01-01

    TM receptors - it is a leucine indicating an altered function. Here, we describe the significance of this position and its possible interaction with TM-3 for CCR5 activity. EXPERIMENTAL APPROACH: The effects of [L203F]-CCR5 in TM-5 (position V:13/5.47), [I116A]-CCR5 in TM-3 (III:16/3.40) and [L203F...... ) with a threefold increase in agonist potency. In silico, [I116A]-CCR5 switched χ1-angle in [L203F]-CCR5. Furthermore, [I116A]-CCR5 was constitutively active to a similar degree as [L203F]-CCR5. Tyr(244) in TM-6 (VI:09/6.44) moved towards TM-5 in silico, consistent with its previously shown function for CCR5...... in the active state, a mechanism proposed previously for the β2 -adrenoceptor. The results provide an understanding of chemokine receptor function and thereby information for the development of biased and non-biased antagonists and inverse agonists....

  17. PRIze{sup TM} 1.2

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-10-01

    PRIze{sup TM} 1.2 is a computer program that evaluates the improved oil recovery (IOR) potential of petroleum reservoirs including the use of horizontal wells. It was created in 1992 and has since been used in over 800 reservoir evaluations. The tool provides information on the feasibility of IOR processes based on reservoir parameters. PRIze{sup TM} makes predictions for chemical, gas injection and thermal IOR processes based on both vertical and horizontal wells. The program provides a uniform data entry screen that allows the user to input 42 average values of geological parameters, fluid properties and oil production mechanism information into a data file. The data can be used to provide a production forecast, and enable the user to establish, to a first order approximation, the economic viability of a given process.

  18. 38 CFR 42.40 - Stays ordered by the Department of Justice.

    Science.gov (United States)

    2010-07-01

    ... 38 Pensions, Bonuses, and Veterans' Relief 2 2010-07-01 2010-07-01 false Stays ordered by the Department of Justice. 42.40 Section 42.40 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS... the Department of Justice. If at any time the Attorney General or Assistant Attorney General...

  19. Spectroscopic analysis and laser performance of Tm3+ : NaGd(MoO4)2 crystal

    International Nuclear Information System (INIS)

    Guo Weijie; Chen Yujin; Lin Yanfu; Gong Xinghong; Luo Zundu; Huang Yidong

    2008-01-01

    Detailed polarized spectral properties of Tm 3+ : NaGd(MoO 4 ) 2 crystal have been investigated. The room temperature absorption and fluorescence spectra were recorded. The fluorescence decay mechanisms of the 1 G 4 and 3 H 4 multiplets in Tm 3+ : NaGd(MoO 4 ) 2 crystal were discussed. Room temperature quasi-cw 1.9 μm laser emission from the Ti : sapphire laser pumped Tm 3+ : NaGd(MoO 4 ) 2 crystal has been demonstrated. The maximum output power of 170 mW has been achieved with a slope efficiency of 25%

  20. High-speed elevator ELEXCIA{sub TM}; Kosoku elevator EXEXCIA{sub TM}

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    New series high-speed elevator ELEXCIA{sub TM} was put on sale in November 1999. In ELEXCIA{sub TM}, the car and door as well as the newly developed hoist and control device were improved in compactness, lightweight, silence, and riding quality. The major features of the high-speed elevator are as follows: (1) The use of an outer rotor-type permanent magnetic synchronous motor (PMSM) in a hoist reduced the mass of the hoist (by about 40% as compared with the conventional one). (2) The use of a double-structured car side plate and floor enabled a silent car. (3) Improved door performance. The introduction of a PMSM motor and latest inverter control processor door into a door gave smoother movement than the previous one. (4) Brightly easy-to-view and white LED-type operation buttons are used in the hoistway door and car. (translated by NEDO)

  1. A Devil in the Details: Matrix-Dependent 40Ca42Ca++/42Ca+ and Its Effects on Estimates of the Initial 41Ca/40Ca in the Solar System

    Science.gov (United States)

    McKeegan, K. D.; Liu, M.-C.

    2015-07-01

    Ian Hutcheon established that the molecular ion interference 40Ca42Ca++/42Ca+ on 41K+ is strongly dependent on the mineral analyzed. Correction for this "matrix effect" led to a downward revision of the initial 41Ca/40Ca of the solar system.

  2. 42 CFR 84.40 - Quality control plans; filing requirements.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Quality control plans; filing requirements. 84.40... Control § 84.40 Quality control plans; filing requirements. As a part of each application for approval or... proposed quality control plan which shall be designed to assure the quality of respiratory protection...

  3. Whole-body retention studies of /sup 167/Tm--citrate. Estimation of radiation dose to humans from /sup 167/Tm--citrate

    Energy Technology Data Exchange (ETDEWEB)

    Hiraki, T; Ando, A [Kanazawa Univ. (Japan). School of Paramedicine; Mori, H; Ando, I; Sakamoto, K

    1978-02-01

    For the purpose of calculating absorbed dose to humans from /sup 167/Tm-citrate, the whole-body retention studies using 5 rats were carried out. Up to 40 days following intravenous injection of /sup 167/Tm-citrate, the whole-body counts were monitored with an animal counter. The whole-body retention curve was obtained with three exponential components. Namely, the 26% of the injected /sup 167/Tm-citrate had a biological half-time of 3.4 hours, 12.5% had a biological half-time of 99 hours and 61.5% had a biological half-time of 106 days. These results indicate, that three components consist of the rapid clearance from the kidneys, the retention in the liver and other soft tissues with relatively long half-time and the retention in the bones with long half-time. Based on these biological data and the MIRD Committee method, the average dose estimates to the bone and whole-body from intravenous administration of 1 mCi /sup 167/Tm-citrate were 7.08 rads and 1.28 rads, respectively.

  4. Combined Analysis of CSF Tau, Aβ42, Aβ1–42% and Aβ1–40ox% in Alzheimer's Disease, Dementia with Lewy Bodies and Parkinson's Disease Dementia

    Directory of Open Access Journals (Sweden)

    Mirko Bibl

    2010-01-01

    Full Text Available We studied the diagnostic value of CSF Aβ42/tau versus low Aβ1–42% and high Aβ1–40ox% levels for differential diagnosis of Alzheimer's disease (AD and dementia with Lewy bodies (DLB, respectively. CSF of 45 patients with AD, 15 with DLB, 21 with Parkinson's disease dementia (PDD, and 40 nondemented disease controls (NDC was analyzed by Aβ-SDS-PAGE/immunoblot and ELISAs (Aβ42 and tau. Aβ42/tau lacked specificity in discriminating AD from DLB and PDD. Best discriminating biomarkers were Aβ1–42% and Aβ1–40ox% for AD and DLB, respectively. AD and DLB could be differentiated by both Aβ1–42% and Aβ1–40ox% with an accuracy of 80% at minimum. Thus, we consider Aβ1–42% and Aβ1–40ox% to be useful biomarkers for AD and DLB, respectively. We propose further studies on the integration of Aβ1–42% and Aβ1–40ox% into conventional assay formats. Moreover, future studies should investigate the combination of Aβ1–40ox% and CSF alpha-synuclein for the diagnosis of DLB.

  5. In-beam γ-ray spectroscopy of 38,40,42Si

    Directory of Open Access Journals (Sweden)

    Matsushita M.

    2014-03-01

    Full Text Available Excited states in the nuclei 38,40,42 Si have been studied using in-beam Γ-ray spectroscopy following multi-nucleon removal reactions to investigate the systematics of excitation energies along the Z=14 isotopic chain. The most probable candidates for the transition from the yrast 4+ state were tentatively assigned among several γ lines newly observed in the present study. The energy ratios between the 21+ and 41+ states were obtained to be 2.09(5, 2.56(5 and 2.93(5 for 38,40,42Si, respectively, indicating a rapid development of deformation in Si isotopes from N=24 to, at least, N=28.

  6. Qualidade de vida de crianças e adolescentes de São Paulo: confiabilidade e validade da versão brasileira do questionário genérico Pediatric Quality of Life InventoryTM versão 4.0 Quality of life of children and adolescents from São Paulo: reliability and validity of the Brazilian version of the Pediatric Quality of Life InventoryTM version 4.0 Generic Core Scales

    Directory of Open Access Journals (Sweden)

    Denise A. Klatchoian

    2008-08-01

    Full Text Available OBJETIVOS: Avaliar a confiabilidade e a validade da versão brasileira do questionário genérico Pediatric Quality of Life InventoryTM (PedsQL TM 4.0 e mensurar a qualidade de vida de crianças e adolescentes saudáveis e de pacientes com doenças reumáticas. MÉTODOS: No processo de validação, seguimos a metodologia proposta pelos idealizadores da versão original em inglês do questionário PedsQL TM 4.0. O instrumento foi administrado por entrevista em dois grupos: 240 crianças e adolescentes aparentemente saudáveis de São Paulo (SP e 105 pacientes com doenças reumáticas crônicas, pareados por idade, e aos respectivos pais ou responsáveis. O questionário foi aplicado nos cuidadores e nas crianças separadamente e no mesmo dia. RESULTADOS: Os valores do teste alfa de Cronbach situaram-se entre 0,6 e 0,9 para todas as dimensões, demonstrando uma consistência interna adequada. Os pacientes com doenças reumáticas apresentaram uma redução significativa na qualidade de vida quando comparados com as crianças saudáveis (p OBJECTIVES: To evaluate the reliability and validity of the Brazilian version of the Pediatric Quality of Life InventoryTM (PedsQL TM 4.0 Generic Core Scales and measure the quality of life of healthy children and adolescents and patients with rheumatic diseases. METHODS: We followed the translation methodology proposed by the developer of the original English version of the PedsQL TM 4.0. The instrument was administered by interviews in two groups: 240 apparently healthy children and adolescents from São Paulo (SP, Brazil and 105 patients with chronic rheumatic diseases, matched by age, as well as to their respective parents or caregivers. The parent proxy-report was administered to the children's parents or caregivers separately on the same day. RESULTS: Cronbach's alpha values were between 0.6 and 0.9 for all dimensions, demonstrating adequate internal consistency. Patients with rheumatic diseases reported

  7. [Study of serum thrombomodulin(TM) levels in patients with hyper- or hypo- thyroidism].

    Science.gov (United States)

    Soma, M; Maeda, Y; Matsuura, R; Sasaki, I; Kasakura, S; Saeki, Y; Ikekubo, K; Ishihara, T; Kurahachi, H; Sasaki, S; Tagami, T; Nakao, K

    1997-01-01

    We studies a relationship between the serum levels of thrombomodulin(TM) and the thyroid functions. Serum TM levels were measured in 48 patients with Graves' disease, 17 patients with primary hypothyroidism, 7 patients with subacute thyroiditis, 5 patients with painless thyroiditis and 2 patients with systematic Refetoff syndrome. These patients did not have malignant tumor, kidney failure, or blood vessel injury. Control sera were obtained from 42 healthy subjects. Serum levels of TM in patients with untreated Graves' disease were significantly higher(p thyroid function(FT3, FT4 and TH) in patients with Graves' disease during treatment showed that both the serum levels of TM and thyroid hormones (FT3 and FT4) lowered progressively during treatment. After normalization of serum FT3 and FT4, the serum TM levels returned to normal. However, the serum levels of TM in patients with destructive thyroiditis and Refetoff syndrome were normal in spite of high serum levels of thyroid hormones. These data suggest that an increase in serum levels of TM is not the direct result of thyroid hormones themselves but is the result of the prolonged hypermetabolic state induced by their peripheral activities. Thyroid hormones may stimulate the synthesis or metabolism of TM on the surface of vascular endothelial cells in the patients with Graves' disease.

  8. Thermal stability and glass-forming ability of amorphous Nd-Al-TM (TM=Fe, Co, Ni or Cu) alloys

    International Nuclear Information System (INIS)

    Inoue, A.; Zhang Tao

    1997-01-01

    Bulk amorphous alloys were prepared for Nd 70 Al 10 TM 20 and Nd 60 Al 10 TM 30 (TM=Fe or Co) alloys by copper mold casting. The maximum sample thickness for glass formation reaches 15 mm for the Nd-Al-Fe alloys and 5 mm for the Nd-Al-Co alloys. A significant difference in the phase transition upon heating is recognized between the Fe- and Co-containing alloys. No glass transition before crystallization is observed for the Nd-Al-Fe alloys, but the Nd-Al-Co alloys exhibit the glass transition. The ΔT x (=T x -T g ) and T g /T m are 40-55 K and 0.65-0.67, respectively, for the latter alloys. The absence of supercooled liquid for the former alloys is different from those for all bulk amorphous alloys reported up to date. The T x /T m and ΔT m (=T m -T x ) are 0.85-0.89 and 88-137 K, respectively, for the Nd-Al-Fe alloys and, hence, the large glass-forming ability is presumably due to the high T x /T m and small ΔT m values. (orig.)

  9. 42 CFR 494.40 - Condition: Water and dialysate quality.

    Science.gov (United States)

    2010-10-01

    ... demonstrate the following: (a) Standard: Water purity. Water and equipment used for dialysis meets the water... Boulevard, Suite 400, Arlington, VA 22201-4598. (b) Standard: Chlorine/chloramines. (1) The water treatment... 42 Public Health 5 2010-10-01 2010-10-01 false Condition: Water and dialysate quality. 494.40...

  10. Efficient infrared (≈1.9-2.0 μm) laser operation in color-defect-free Tm:NaGd(MoO4)2 crystal

    Science.gov (United States)

    Han, X.; Rico, M.; Serrano, M. D.; Cascales, C.; Zaldo, C.

    2013-04-01

    Color-defect-free 5 at.% Tm:NaGd(MoO4)2 crystals have been grown in a Na2MoO4/Na2Mo2O7 flux. Using a hemispherical optical cavity and pumping at λ = 794.5 nm with a Ti-sapphire laser, up to 850 mW of output power at λ ≈ 1900 nm was obtained at 300 K with an output coupler transmission of 8%. In the cw regime, the slope efficiency versus absorbed power was η = 45% and the pump power laser threshold was ≈180 mW. The laser was tunable from 1875 to 1975 nm and the emission had a FWHM bandwidth ≈20 nm, indicating the potential for ultrashort laser pulse generation.

  11. Plasma antibodies to Abeta40 and Abeta42 in patients with Alzheimer's disease and normal controls.

    Science.gov (United States)

    Xu, Wuhua; Kawarabayashi, Takeshi; Matsubara, Etsuro; Deguchi, Kentaro; Murakami, Tetsuro; Harigaya, Yasuo; Ikeda, Masaki; Amari, Masakuni; Kuwano, Ryozo; Abe, Koji; Shoji, Mikio

    2008-07-11

    Antibodies to amyloid beta protein (Abeta) are present naturally or after Abeta vaccine therapy in human plasma. To clarify their clinical role, we examined plasma samples from 113 patients with Alzheimer's disease (AD) and 205 normal controls using the tissue amyloid plaque immunoreactivity (TAPIR) assay. A high positive rate of TAPIR was revealed in AD (45.1%) and age-matched controls (41.2%), however, no significance was observed. No significant difference was observed in the MMS score or disease duration between TAPIR-positive and negative samples. TAPIR-positive plasma reacted with the Abeta40 monomer and dimer, and the Abeta42 monomer weakly, but not with the Abeta42 dimer. TAPIR was even detected in samples from young normal subjects and young Tg2576 transgenic mice. Although the Abeta40 level and Abeta40/42 ratio increased, and Abeta42 was significantly decreased in plasma from AD groups when compared to controls, no significant correlations were revealed between plasma Abeta levels and TAPIR grading. Thus an immune response to Abeta40 and immune tolerance to Abeta42 occurred naturally in humans without a close relationship to the Abeta burden in the brain. Clarification of the mechanism of the immune response to Abeta42 is necessary for realization of an immunotherapy for AD.

  12. Concentration effect of Tm3+ on cathodoluminescence properties of SiO2: Tm3+ and SiO2:Ho3+, Tm3+ systems

    CSIR Research Space (South Africa)

    Dhlamini, MS

    2012-05-01

    Full Text Available .physb.2011.09.091 Concentration effect of Tm3+ on cathodoluminescence properties of SiO2: Tm 3+ and SiO2:Ho 3+, Tm3+ systems M.S. Dhlamini, G.H. Mhlongo, H.C. Swart, O.M. Ntwaeaborwa, K.T. Hillie ABSTRACT: Cathodoluminescence (CL) properties of Si...O2 powders activated with thulium (Tm3+) and holmium (Ho3+) ions prepared by a sol–gel process were investigated. Different molar concentrations of Tm3+ co-doped with Ho3+ were studied. The 460 nm peak was monitored and the influence of the beam...

  13. X-ray diffraction and electron microscopy data for amyloid formation of Aβ40 and Aβ42

    Directory of Open Access Journals (Sweden)

    Olga M. Selivanova

    2016-09-01

    Full Text Available The data presented in this article are related to the research article entitled “One of the possible mechanisms of amyloid fibrils formation based on the sizes of primary and secondary folding nuclei of Aβ40 and Aβ42” (Dovidchenko et al., 2016 [1]. Aβ peptide is one of the most intensively studied amyloidogenic peptides. Despite the huge number of articles devoted to studying different fragments of Aβ peptide there are only several papers with correct kinetics data, also there are a few papers with X-ray data, especially for Aβ42. Our data present X-ray diffraction patterns both for Aβ40 and Aβ42 as well for Tris–HCl and wax. Moreover, our data provide kinetics of amyloid formation by recombinant Аβ40 and synthetic Аβ42 peptides by using electron microscopy.

  14. Quantification of left ventricular function by gated myocardial perfusion SPECT using multidimTM

    International Nuclear Information System (INIS)

    Huang Jin; Song Wenzhong; Chen Mingxi

    2004-01-01

    Objective: To evaluate the accuracy of left ventricular function by gated SPECT using the software Multidim TM . Methods: Rest gated SPECT was performed on 42 cases involved 26 normal subjects and 16 patients with myocardial infarct (MI). All cases underwent rest equilibrium radionuclide angiocardiography (ERNA) within 1 w. Results: (1)End diastolic volume (EDV), end systolic volume (ESV) and left ventricular ejection fraction(LVEF)were calculated using the software MultidimtMand ERNA. The correlation coefficient between the two Methods was 0.90,0.89,0.92 respectively(P TM , but the EDV and ESV value measured by this software maybe high with small heart. (authors)

  15. 40 CFR 81.42 - Chattanooga Interstate Air Quality Control Region.

    Science.gov (United States)

    2010-07-01

    ... Quality Control Regions § 81.42 Chattanooga Interstate Air Quality Control Region. The Chattanooga Interstate Air Quality Control Region (Georgia-Tennessee) has been revised to consist of the territorial area... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Chattanooga Interstate Air Quality...

  16. Powernext Day-AheadTM. Powernext futuresTM. Activity report - 2004

    International Nuclear Information System (INIS)

    2004-01-01

    The introduction of a power exchange in France is a direct response to the opening up of the European electricity markets. Powernext SA is a Multilateral Trading Facility in charge of managing the French power exchange through an optional and anonymous organised exchange offering: - Day-ahead contracts for the management of volume risk on Powernext Day-Ahead TM since 21 November 2001, - Medium term contracts for the management of price risk on Powernext Futures TM since 18 June 2004. This document is the 2004 activity report of Powernext SA, it presents the key figures of the power market and of Powernext in 2004: - Increasing volumes: Powernext Day-Ahead TM 's traded volumes increased by 89%, from 7.48 to 14.18 TWh. Powernext Futures TM kicks off to a promising debut with 12.86 TWh traded in less than 7 months. - Less volatile prices: During 2004, the base price averaged 28.13 euro/MWh, and the peak prices averaged 33.71 euro/MWh. Compared to 2003, these prices decreased by an average of 3.7% on base-load and 10.9% on peak-load. In comparison to the two previous years, the daily volatility has noticeably settled down with 27% on base-load and 37% on peak-load. - Increasing liquidity: 10 new members joined Powernext Day-Ahead TM in 2004. The activity level of the members remains very high as 89% of them trade on an actual daily basis during 2004. The market resiliency stays strong. In December, an additional market 50 MW order on each hour resulted in a balance price variation of only 0.16 euro/MWh, or 0.53% of this balance price. For a 100 MW order, the resiliency is 0.32 euro/MWh, or 1.07% of the balance price. Thus, in 2004, Powernext Day-Ahead TM consolidates its role as a short term reference price. Moreover, in 2004, Powernext launched a futures market, Powernext Futures TM . This new market segment proposes contracts tradable up to 2 years ahead of delivery

  17. Diode-pumped efficient laser operation and spectroscopy of Tm,Ho:YVO 4

    Science.gov (United States)

    Li, G.; Yao, B. Q.; Meng, P. B.; Duan, X. M.; Ju, Y. L.; Wang, Y. Z.

    2011-04-01

    Spectroscopic characterization of co-doped Tm,Ho:YVO 4 crystal grown by the Czochralski method has been performed including absorption spectrum, emitting spectrum and luminescence decay lifetime. The polarization emitting spectrum around 2 μm is accomplished by exciting a singly Ho 3+ doped YVO 4 crystal to exclude the influence of Tm 3+3F 4- 3H 6 transition and the emission cross section is deduced from both Fuchtbauer-Ladenburg (F-L) equation and reciprocity method (RM). In addition, we report up to 10.4 W continuous wave (CW) output with a conversion efficiency of 40% and 10.3 W Q-Switch output with 12.5 kHz pulse repetition rate of diode-pumped cryogenic Tm,Ho:YVO 4 laser. For Q-Switch operation, the minimum pulse width of 28.2 ns is obtained, all of which demonstrate that the Tm,Ho:YVO 4 is excellent laser material for 2 μm radiation.

  18. The tmRDB and SRPDB resources

    DEFF Research Database (Denmark)

    Andersen, Ebbe Sloth; Rosenblad, Magnus Alm; Larsen, Niels

    2006-01-01

    Maintained at the University of Texas Health Science Center at Tyler, Texas, the tmRNA database (tmRDB) is accessible at the URL http://psyche.uthct.edu/dbs/tmRDB/tmRDB.html with mirror sites located at Auburn University, Auburn, Alabama (http://www.ag.auburn.edu/mirror/tmRDB/) and the Royal...

  19. Magnetic ordering in TmGa

    DEFF Research Database (Denmark)

    Cadogan, J.M.; Stewart, G.A.; Muños Pérez, S.

    2014-01-01

    We have determined the magnetic structure of the intermetallic compound TmGa by high-resolution neutron powder diffraction and 169Tm Mössbauer spectroscopy. This compound crystallizes in the orthorhombic (Cmcm) CrB-type structure and its magnetic structure is characterized by magnetic order...... of the Tm sublattice along the a-axis. The initial magnetic ordering occurs at 15(1) K and yields an incommensurate antiferromagnetic structure described by the propagation vector k1 = [0 0.275(2) 0]. At 12 K the dominant ferromagnetic ordering of the Tm sublattice along the a-axis develops in what appears...... to be a first-order transition. At 3 K the magnetic structure of TmGa is predominantly ferromagnetic but a weakened incommensurate component remains. The ferromagnetic Tm moment reaches 6.7(2) μB at 3 K and the amplitude of the remaining incommensurate component is 2.7(4) μB. The 169Tm hyperfine magnetic field...

  20. Lyme Disease and YouTube TM: A Cross-Sectional Study of Video Contents.

    Science.gov (United States)

    Basch, Corey H; Mullican, Lindsay A; Boone, Kwanza D; Yin, Jingjing; Berdnik, Alyssa; Eremeeva, Marina E; Fung, Isaac Chun-Hai

    2017-08-01

    Lyme disease is the most common tick-borne disease. People seek health information on Lyme disease from YouTube TM videos. In this study, we investigated if the contents of Lyme disease-related YouTube TM videos varied by their sources. Most viewed English YouTube TM videos (n = 100) were identified and manually coded for contents and sources. Within the sample, 40 videos were consumer-generated, 31 were internet-based news, 16 were professional, and 13 were TV news. Compared with consumer-generated videos, TV news videos were more likely to mention celebrities (odds ratio [OR], 10.57; 95% confidence interval [CI], 2.13-52.58), prevention of Lyme disease through wearing protective clothing (OR, 5.63; 95% CI, 1.23-25.76), and spraying insecticides (OR, 7.71; 95% CI, 1.52-39.05). A majority of the most popular Lyme disease-related YouTube TM videos were not created by public health professionals. Responsible reporting and creative video-making facilitate Lyme disease education. Partnership with YouTube TM celebrities to co-develop educational videos may be a future direction.

  1. Translation-Memory (TM) Research

    DEFF Research Database (Denmark)

    Schjoldager, Anne Gram; Christensen, Tina Paulsen

    2010-01-01

    to be representative of the research field as a whole. Our analysis suggests that, while considerable knowledge is available about the technical side of TMs, more research is needed to understand how translators interact with TM technology and how TMs influence translators' cognitive translation processes.......  It is no exaggeration to say that the advent of translation-memory (TM) systems in the translation profession has led to drastic changes in translators' processes and workflow, and yet, though many professional translators nowadays depend on some form of TM system, this has not been the object...... of much research. Our paper attempts to find out what we know about the nature, applications and influences of TM technology, including translators' interaction with TMs, and also how we know it. An essential part of the analysis is based on a selection of empirical TM studies, which we assume...

  2. 41 CFR 102-42.40 - When is an appraisal necessary?

    Science.gov (United States)

    2010-07-01

    ... DISPOSAL OF FOREIGN GIFTS AND DECORATIONS General Provisions Appraisals § 102-42.40 When is an appraisal necessary? An appraisal is necessary when— (a) An employee indicates an interest in purchasing a gift or decoration. In this situation, the appraisal must be obtained before the gift or decoration is reported to...

  3. Cross-Section Measurement of the 169Tm(n,3n)167Tm Reaction and Constraining the Branching Ratio of 167Tm

    Science.gov (United States)

    Champine, Brian; Gooden, Matthew; Thomas, Keenan; Krishichayan, F.; Norman, Eric; Scielzo, Nick; Tonchev, Anton; Tornow, Werner

    2015-10-01

    The cross section of the 169Tm(n,3n)167Tm reaction has been measured from 17.5 to 21.5 MeV using activation technique. This energy region was chosen to resolve the two different trends of the previous (n,3n) cross section measurements on 169Tm. In addition, the branching ratio of the 207.8 keV γ-ray line stemming from electron capture of 167Tm was measured to be 0.419(16). The result of these measurements provide more accurate diagnostic estimation of the so called reaction-in-flight neutrons produced via the internal confinement fusion plasma in deuterium-tritium capsules at the National Ignition Facility.

  4. Comparative study of Tm-doped and Tm-Sc co-doped Lu3Al5O12 scintillator

    International Nuclear Information System (INIS)

    Sugiyama, Makoto; Yanagida, Takayuki; Fujimoto, Yutaka

    2014-01-01

    The crystals of Tm doped and Tm-Sc co-doped Lu 3 Al 5 O 12 (LuAG) grown by the floating zone (FZ) method were examined for their optical and scintillation properties. In transmittance spectra, strong absorption lines due to Tm 3+ 4f–4f transitions were observed. X-ray excited radioluminescence spectra were measured and broad and sharp emission peaks were detected. The former one was attributed to Sc 3+ and the latter one was due to Tm 3+ 4f–4f transitions. Scintillation yield enhancement due to Sc co-doping was observed by means of 137 Cs pulse height spectra. Scintillation decay times were several tens of μs under pulse X-ray excitation. - Highlights: • LuAG:Tm and LuAG:Tm, Sc single crystals have been grown by the FZ method. • Tm 3+ 4f–4f absorption has been observed in transmittance spectra. • Scintillation yield of Tm-doped LuAG has been enhanced by Sc co-doping

  5. 1887 nm lasing in Tm3+-doped TeO2-BaF2-Y2O3 glass microstructured fibers

    Science.gov (United States)

    Wang, Shunbin; Yao, Chuanfei; Jia, Zhixu; Qin, Guanshi; Qin, Weiping

    2017-04-01

    In this paper, we demonstrate ∼2 μm lasing in Tm3+-doped fluorotellurite microstructured fibers. The Tm3+-doped fibers are based on TeO2-BaF2-Y2O3 glasses and fabricated by using a rod-in-tube method. Under the pump of a 1570 nm Er3+-doped fiber laser, lasing at 1887 nm is obtained in a ∼42.5 cm long Tm3+-doped fiber with a threshold pump power of 94 mW. As the pump power increases to 780 mW, the obtained maximum unsaturated power reaches up to ∼408 mW with a slop efficiency of ∼58.1%. This result indicates that the Tm3+-doped fluorotellurite fibers are promising gain media for ∼2 μm fiber lasers.

  6. PheVI:09 (Phe6.44) as a sliding microswitch in seven-transmembrane (7TM) G protein-coupled receptor activation

    DEFF Research Database (Denmark)

    Valentin-Hansen, Louise; Holst, Birgitte; Frimurer, Thomas M

    2012-01-01

    In seven-transmembrane (7TM), G protein-coupled receptors, highly conserved residues function as microswitches, which alternate between different conformations and interaction partners in an extended allosteric interface between the transmembrane segments performing the large scale conformational......-V into a tight pocket generated by five hydrophobic residues protruding from TM-III and TM-V. Of these, the residue in position III:16 (3.40) (often an Ile or Val) appears to function as a barrier or gate for the transition between inactive and active conformation. Mutational analysis showed that PheVI:09...... an aromatic microswitch that stabilizes the active, outward tilted conformation of TM-VI relative to TM-III by sliding into a tight hydrophobic pocket between TM-III and TM-V and that the hydrophobic residue in position III:16 constitutes a gate for this transition....

  7. Dimer formation enhances structural differences between amyloid β-protein (1-40 and (1-42: an explicit-solvent molecular dynamics study.

    Directory of Open Access Journals (Sweden)

    Bogdan Barz

    Full Text Available Amyloid β-protein (Aβ is central to the pathology of Alzheimer's disease. A 5% difference in the primary structure of the two predominant alloforms, Aβ(1-40 and Aβ(1-42, results in distinct assembly pathways and toxicity properties. Discrete molecular dynamics (DMD studies of Aβ(1-40 and Aβ(1-42 assembly resulted in alloform-specific oligomer size distributions consistent with experimental findings. Here, a large ensemble of DMD-derived Aβ(1-40 and Aβ(1-42 monomers and dimers was subjected to fully atomistic molecular dynamics (MD simulations using the OPLS-AA force field combined with two water models, SPCE and TIP3P. The resulting all-atom conformations were slightly larger, less compact, had similar turn and lower β-strand propensities than those predicted by DMD. Fully atomistic Aβ(1-40 and Aβ(1-42 monomers populated qualitatively similar free energy landscapes. In contrast, the free energy landscape of Aβ(1-42 dimers indicated a larger conformational variability in comparison to that of Aβ(1-40 dimers. Aβ(1-42 dimers were characterized by an increased flexibility in the N-terminal region D1-R5 and a larger solvent exposure of charged amino acids relative to Aβ(1-40 dimers. Of the three positively charged amino acids, R5 was the most and K16 the least involved in salt bridge formation. This result was independent of the water model, alloform, and assembly state. Overall, salt bridge propensities increased upon dimer formation. An exception was the salt bridge propensity of K28, which decreased upon formation of Aβ(1-42 dimers and was significantly lower than in Aβ(1-40 dimers. The potential relevance of the three positively charged amino acids in mediating the Aβ oligomer toxicity is discussed in the light of available experimental data.

  8. ∼2 μm fluorescence radiative dynamics and energy transfer between Er3+ and Tm3+ ions in silicate glass

    International Nuclear Information System (INIS)

    Li, Ming; Liu, Xueqiang; Guo, Yanyan; Hao, Wei; Hu, Lili; Zhang, Junjie

    2014-01-01

    Graphical abstract: - Highlights: • A Er 3+ /Tm 3+ co-doped silicate glass with good thermal stability (k gl = 0.402 for STE glass) is prepared. • Efficient ∼2 μm emission is observed under 808 nm and 980 nm laser excitation. • The glass structure and spectroscopic properties are confirmed by optical absorption, IR transmission, Raman and fluorescence studies. • The content of OH groups deceases efficiently after fluorine ions are introduced. • The energy transfer coefficient from Er 3+ to Tm 3+ in STFE glass is 13.39 × 10 −40 cm 6 /s. - Abstract: A Er 3+ /Tm 3+ co-doped silicate glass with good thermal stability is prepared by melt-quenching method. An efficient emission of ∼2 μm is observed under different selective laser excitations. The optical absorption and transmission spectra, Raman spectra, and emission spectra are tested to characterize ∼2 μm emission properties of Er 3+ /Tm 3+ co-doped silicate glasses and a reasonable energy transfer mechanism of ∼2 μm emission between Er 3+ and Tm 3+ ions is proposed. Based on the optical absorption spectra, the Judd–Ofelt parameters and radiative properties were calculated. Intense ∼2 μm emission is obtained from Er 3+ /Tm 3+ co-doped silicate glasses due to the efficient energy transfer from Er 3+ to Tm 3+ ions. The energy transfer coefficient from Er 3+ to Tm 3+ ions can reach as high as 13.39 × 10 −40 cm 6 /s. In addition, the population of the OH groups is decreased and the ∼2 μm emission is effectively enhanced with fluoride introduction. The emission property, together with good thermal property, indicates that Er 3+ /Tm 3+ co-doped silicate glass is a potential kind of laser glass for efficient ∼2 μm laser

  9. Recommendations on AECB draft licensing guides nos. 40,41,42

    International Nuclear Information System (INIS)

    1981-06-01

    This report contains the recommendations of the Advisory Committee on Nuclear Safety (ACNS) to the Atomic Energy Control Board concerning the draft AECB Licensing Guides 40, 41 and 42 which were issued subsequently as Consultative Documents Nos. 7, 8 and 9. Since the report focusses on points of principle or generic concern, most of its recommendations apply generally to all three documents, although some specific recommendations are included [fr

  10. Culture-independent detection of 'TM7' bacteria in a streptomycin-resistant acidophilic nitrifying process

    Energy Technology Data Exchange (ETDEWEB)

    Kurogi, T.; Linh, N. T. T.; Kuroki, T.; Yamada, T. [Department of Environmental and Life Science, Toyohashi University of Technology, Toyohashi 441-8580 (Japan); Hiraishi, A. [Department of Environmental and Life Science, Toyohashi University of Technology, Toyohashi 441-8580, Japan and Electronics-inspired Interdisciplinary Institute (EIIRIS), Toyohashi University of Technology, Toyohashi 441-8580 (Japan)

    2014-02-20

    Nitrification in biological wastewater treatment processes has been believed for long time to take place under neutral conditions and is inhibited under acidic conditions. However, we previously constructed acidophilic nitrifying sequencing-batch reactors (ANSBRs) being capable of nitrification at < pH 4 and harboring bacteria of the candidate phylum 'TM7' as the major constituents of the microbial community. In light of the fact that the 16S rRNA of TM7 bacteria has a highly atypical base substitution possibly responsible for resistance to streptomycin at the ribosome level, this study was undertaken to construct streptomycin-resistant acidophilic nitrifying (SRAN) reactors and to demonstrate whether TM7 bacteria are abundant in these reactors. The SRAN reactors were constructed by seeding with nitrifying sludge from an ANSBR and cultivating with ammonium-containing mineral medium (pH 4.0), to which streptomycin at a concentration of 10, 30 and 50 mg L{sup −1} was added. In all reactors, the pH varied between 2.7 and 4.0, and ammonium was completely converted to nitrate in every batch cycle. PCR-aided denaturing gradient gel electrophoresis (DGGE) targeting 16S rRNA genes revealed that some major clones assigned to TM7 bacteria and Gammaproteobacteria were constantly present during the overall period of operation. Fluorescence in situ hybridization (FISH) with specific oligonucleotide probes also showed that TM7 bacteria predominated in all SRAN reactors, accounting for 58% of the total bacterial population on average. Although the biological significance of the TM7 bacteria in the SRAN reactors are unknown, our results suggest that these bacteria are possibly streptomycin-resistant and play some important roles in the acidophilic nitrifying process.

  11. RangerMasterTM: real-time pattern recognition software for in-field analysis of radiation sources

    International Nuclear Information System (INIS)

    Murray, W.S.; Ziemba, F.; Szluk, N.

    1998-01-01

    RangerMaster TM is the embedded firmware for Quantrad Sensor's integrated nuclear instrument package, the Ranger TM . The Ranger TM , which is both a gamma-ray and neutron detection system, was originally developed at Los Alamos National Laboratory for in situ surveys at the Plutonium Facility to confirm the presence of nuclear materials. The new RangerMaster TM software expands the library of isotopes and simplifies the operation of the instrument by providing an 'easy' mode suitable for untrained operators. The expanded library of the Ranger TM now includes medical isotopes 99 Tc, 201 Tl, 111 In, 67 Ga, 133 Xe, 103 Pa, and 131 I; industrial isotopes 241 Am, 57 Co, 133 Ba, 137 Cs, 40 K, 60 Co, 232 Th, 226 Ra, and 207 Bi; and nuclear materials 235 U, 238 U, 233 U, and 239 Pu. To accomplish isotopic identification, a simulated spectrum for each of the isotopes was generated using SYNTH 2 . The SYNTH spectra formed the basis for the knowledge-based expert system and selection of the regions of interest that are used in the pattern recognition system. The knowledge-based pattern recognition system was tested against actual spectra under field conditions. (author)

  12. 76 FR 27861 - Airworthiness Directives; Diamond Aircraft Industries GmbH Models DA 42, DA 42 NG, and DA 42 M-NG...

    Science.gov (United States)

    2011-05-13

    ... Airworthiness Directives; Diamond Aircraft Industries GmbH Models DA 42, DA 42 NG, and DA 42 M-NG Airplanes... on Diamond aeroplanes, the majority of which were DA 40. In additional, at least 18 doors have been... conditions) while the aeroplane was parked. All DA 40 and DA 42 aeroplanes have a system installed that...

  13. Secondary Forest Age and Tropical Forest Biomass Estimation Using TM

    Science.gov (United States)

    Nelson, R. F.; Kimes, D. S.; Salas, W. A.; Routhier, M.

    1999-01-01

    The age of secondary forests in the Amazon will become more critical with respect to the estimation of biomass and carbon budgets as tropical forest conversion continues. Multitemporal Thematic Mapper data were used to develop land cover histories for a 33,000 Square kM area near Ariquemes, Rondonia over a 7 year period from 1989-1995. The age of the secondary forest, a surrogate for the amount of biomass (or carbon) stored above-ground, was found to be unimportant in terms of biomass budget error rates in a forested TM scene which had undergone a 20% conversion to nonforest/agricultural cover types. In such a situation, the 80% of the scene still covered by primary forest accounted for over 98% of the scene biomass. The difference between secondary forest biomass estimates developed with and without age information were inconsequential relative to the estimate of biomass for the entire scene. However, in futuristic scenarios where all of the primary forest has been converted to agriculture and secondary forest (55% and 42% respectively), the ability to age secondary forest becomes critical. Depending on biomass accumulation rate assumptions, scene biomass budget errors on the order of -10% to +30% are likely if the age of the secondary forests are not taken into account. Single-date TM imagery cannot be used to accurately age secondary forests into single-year classes. A neural network utilizing TM band 2 and three TM spectral-texture measures (bands 3 and 5) predicted secondary forest age over a range of 0-7 years with an RMSE of 1.59 years and an R(Squared) (sub actual vs predicted) = 0.37. A proposal is made, based on a literature review, to use satellite imagery to identify general secondary forest age groups which, within group, exhibit relatively constant biomass accumulation rates.

  14. 76 FR 12627 - Airworthiness Directives; Diamond Aircraft Industries GmbH Models DA 42, DA 42 NG, and DA 42 M-NG...

    Science.gov (United States)

    2011-03-08

    ... Industries GmbH Models DA 42, DA 42 NG, and DA 42 M-NG Airplanes AGENCY: Federal Aviation Administration (FAA... on Diamond aeroplanes, the majority of which were DA 40. In additional, at least 18 doors have been... conditions) while the aeroplane was parked. All DA 40 and DA 42 aeroplanes have a system installed that...

  15. Formation and characterization of ZnO : Tm+ optical waveguides fabricated by Tm+ and O+ ion implantation

    International Nuclear Information System (INIS)

    Ming Xianbing; Lu Fei; Liu Hanping; Chen Ming; Wang Lei

    2009-01-01

    Planar optical waveguides were formed in ZnO crystal by Tm + and O + ion implantation. The distributions of Tm + in as-implanted and annealed ZnO samples were investigated by the RBS technique. A shift of the Tm + peak towards the sample surface and out diffusion were observed after thermal treatment and subsequent O + ion implantation. Waveguide formation was determined after O + implantation in Tm + -implanted ZnO crystal. By using the prism-coupling method two guided modes were detected. The refractive index profile in the implanted waveguide was reconstructed according to the SRIM and RCM simulation. The RBS/channelling measurements show that the lattice structure of ZnO did not suffer detectable damage after O + implantation.

  16. Temperature dependence of LRE-HRE-TM thin films

    Science.gov (United States)

    Li, Zuoyi; Cheng, Xiaomin; Lin, Gengqi; Li, Zhen; Huang, Zhixin; Jin, Fang; Wang, Xianran; Yang, Xiaofei

    2003-04-01

    Temperature dependence of the properties of RE-TM thin films is very important for MO recording. In this paper, we studied the temperature dependence of the magnetic and magneto-optical properties of the amorphous LRE-HRE-TM single layer thin films and LRE-HRE-TM/HRE-TM couple-bilayered thin films. For LRE-HRE-TM single layer thin films, the temperature dependence of the magnetization was investigated by using the mean field theory. The experimental and theoretical results matched very well. With the LRE substitution in HRE-TM thin film, the compensation temperature Tcomp decreased and the curie temperature Tc remained unchanged. Kerr rotation angle became larger and the saturation magnetization Ms at room temperature increased. For LRE-HRE-TM/HRE-TM couple-bilayered thin films, comparisons of the temperature dependences of the coercivities and Kerr rotation angles were made between isolated sublayers and couple-bilayered thin film.

  17. Measurement of the 169Tm (n ,3 n ) 167Tm cross section and the associated branching ratios in the decay of 167Tm

    Science.gov (United States)

    Champine, B.; Gooden, M. E.; Krishichayan, Norman, E. B.; Scielzo, N. D.; Stoyer, M. A.; Thomas, K. J.; Tonchev, A. P.; Tornow, W.; Wang, B. S.

    2016-01-01

    The cross section for the 169Tm(n ,3 n ) 167Tm reaction was measured from 17 to 22 MeV using quasimonoenergetic neutrons produced by the 2H(d ,n ) 3He reaction. This energy range was studied to resolve the discrepancy between previous (n ,3 n ) cross-section measurements. In addition, the absolute γ -ray branching ratios following the electron-capture decay of 167Tm were measured. These results provide more reliable nuclear data for an important diagnostic that is used at the National Ignition Facility to estimate the yield of reaction-in-flight neutrons produced via the inertial-confinement-fusion plasma in deuterium-tritium capsules.

  18. Effect and mode of action of the Texel muscling QTL (TM-QTL) on carcass traits in purebred Texel lambs.

    Science.gov (United States)

    Macfarlane, J M; Lambe, N R; Matika, O; Johnson, P L; Wolf, B T; Haresign, W; Bishop, S C; Bünger, L

    2014-07-01

    TM-QTL is a quantitative trait locus (QTL) on ovine chromosome 18 (OAR18) known to affect loin muscling in Texel sheep. Previous work suggested that its mode of inheritance is consistent with paternal polar overdominance, but this has yet to be formally demonstrated. This study used purebred Texel sheep segregating for TM-QTL to confirm its presence in the chromosomal region in which it was first reported and to determine its pattern of inheritance. To do so, this study used the first available data from a Texel flock, which included homozygote TM-QTL carriers (TM/TM; n=34) in addition to homozygote non-carriers (+/+; n=40 and, heterozygote TM-QTL-carriers inheriting TM-QTL from their sire (TM/+; n=53) or their dam (+/TM; n=17). Phenotypes included a wide range of loin muscling, carcass composition and tissue distribution traits. The presence of a QTL affecting ultrasound muscle depth on OAR18 was confirmed with a paternal QTL effect ranging from +0.54 to +2.82 mm UMD (s.e. 0.37 to 0.57 mm) across the sires segregating for TM-QTL. Loin muscle width, depth and area, loin muscle volume and dissected M. longissimus lumborum weight were significantly greater for TM/+ than +/+ lambs (+2.9% to +7.9%; Pcarcass weight; TM/TM animals were significantly (Panimals (+11.9% and +11.7%, respectively), with TM/+ intermediate. Weights of the leg, saddle and shoulder region (corrected for carcass weight) were similar in the genotypic groups. There was a tendency for lambs inheriting TM-QTL from their sire to be less fat with slightly more muscle than non-carriers. For example, carcass muscle weight measured by live animal CT-scanning was 2.8% higher in TM/TM than +/+ lambs (Pcarcass muscle weight measured by carcass CT-scanning was 1.36% higher in TM/+ than +/+ lambs (Pcarcass cuts was significantly lower for TM/+ than +/+ lambs (-11.2%; Pcarcass traits were found. Optimal commercial use of TM-QTL within the sheep industry would require some consideration, due to the apparently

  19. Virally encoded 7TM receptors

    DEFF Research Database (Denmark)

    Rosenkilde, M M; Waldhoer, M; Lüttichau, H R

    2001-01-01

    expression of this single gene in certain lymphocyte cell lineages leads to the development of lesions which are remarkably similar to Kaposi's sarcoma, a human herpesvirus 8 associated disease. Thus, this and other virally encoded 7TM receptors appear to be attractive future drug targets.......A number of herpes- and poxviruses encode 7TM G-protein coupled receptors most of which clearly are derived from their host chemokine system as well as induce high expression of certain 7TM receptors in the infected cells. The receptors appear to be exploited by the virus for either immune evasion...

  20. Structural, mechanical and electronic properties of OsTM and TMOs{sub 2} (TM = Ti, Zr and Hf): First-principles calculations

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Qi-Jun, E-mail: qijunliu@home.swjtu.edu.cn [Bond and Band Engineering Group, Institute of High Temperature and High Pressure Physics, School of Physical Science and Technology, Southwest Jiaotong University, Chengdu, Sichuan 610031 (China); Zhang, Ning-Chao; Liu, Fu-Sheng [Bond and Band Engineering Group, Institute of High Temperature and High Pressure Physics, School of Physical Science and Technology, Southwest Jiaotong University, Chengdu, Sichuan 610031 (China); Liu, Zheng-Tang [State Key Laboratory of Solidification Processing, School of Materials Science and Engineering, Northwestern Polytechnical University, Xi’an, Shaanxi 710072 (China)

    2014-03-15

    Highlights: • OsTM and TMOs{sub 2} compounds have no superhard character. • These compounds are mechanically stable and behave in ductile manner. • OsTM has a mixture of covalent-ionic and metallic character. -- Abstract: The first-principles calculations have been performed to study the structural, elastic, mechanical and electronic properties of cubic OsTM (TM = Ti, Zr, and Hf) and hexagonal TMOs{sub 2} compounds. The calculated structural parameters are in good agreement with the available experimental data. To the best of our knowledge, the elastic constants of OsTM and TMOs{sub 2} compounds have been obtained for the first time. The calculated elastic and mechanical properties show that these compounds have no superhard character. These compounds are mechanically stable and behave in ductile manner. The electronic band structures and densities of states of OsTM and TMOs{sub 2} compounds have been analysed. OsTM has a mixture of covalent-ionic and metallic character, and TMOs{sub 2} has strong metallic nature.

  1. Comparison of NMR and crystal structures for the proteins TM1112 and TM1367

    International Nuclear Information System (INIS)

    Mohanty, Biswaranjan; Serrano, Pedro; Pedrini, Bill; Jaudzems, Kristaps; Geralt, Michael; Horst, Reto; Herrmann, Torsten; Elsliger, Marc-André; Wilson, Ian A.; Wüthrich, Kurt

    2010-01-01

    NMR structures of the proteins TM1112 and TM1367 solved by the JCSG in solution at 298 K could be superimposed with the corresponding crystal structures at 100 K with r.m.s.d. values of <1.0 Å for the backbone heavy atoms. For both proteins the structural differences between multiple molecules in the asymmetric unit of the crystals correlated with structural variations within the bundles of conformers used to represent the NMR solution structures. A recently introduced JCSG NMR structure-determination protocol, which makes use of the software package UNIO for extensive automation, was further evaluated by comparison of the TM1112 structure obtained using these automated methods with another NMR structure that was independently solved in another PSI center, where a largely interactive approach was applied. The NMR structures of the TM1112 and TM1367 proteins from Thermotoga maritima in solution at 298 K were determined following a new protocol which uses the software package UNIO for extensive automation. The results obtained with this novel procedure were evaluated by comparison with the crystal structures solved by the JCSG at 100 K to 1.83 and 1.90 Å resolution, respectively. In addition, the TM1112 solution structure was compared with an NMR structure solved by the NESG using a conventional largely interactive methodology. For both proteins, the newly determined NMR structure could be superimposed with the crystal structure with r.m.s.d. values of <1.0 Å for the backbone heavy atoms, which provided a starting platform to investigate local structure variations, which may arise from either the methods used or from the different chemical environments in solution and in the crystal. Thereby, these comparative studies were further explored with the use of reference NMR and crystal structures, which were computed using the NMR software with input of upper-limit distance constraints derived from the molecular models that represent the results of structure

  2. Spectral and power characteristics of a 5% Tm : KLu(WO4)2 Nm-cut minislab laser passively Q-switched by a Cr2+ : ZnSe crystal

    Science.gov (United States)

    Vatnik, S. M.; Vedin, I. A.; Kurbatov, P. F.; Smolina, E. A.; Pavlyuk, A. A.; Korostelin, Yu. V.; Skasyrsky, Ya. K.

    2017-12-01

    Laser characteristics of a 5%Tm : KLu(WO4)2 Nm-cut minislab laser passively Q-switched by a Cr2+ : ZnSe saturable absorber are presented. At a pump power of 21 W, the average laser power at a wavelength of 1.91 μm was 3.2 W (pulse duration 35 ns, pulse energy 0.3 mJ). The maximum slope efficiency of the laser in the Q-switched regime was 31%; the loss in power with respect to the cw regime did not exceed 17%. At pump powers above 15 W, the dependence of the output power in the Q-switched regime on the pump power considerably differed from linear, which was explained by the formation of a thermal lens in the saturable absorber volume. The experimental energies and durations of laser pulses well agree with the values calculated from rate equations.

  3. Culture-independent detection of 'TM7' bacteria in a streptomycin-resistant acidophilic nitrifying process

    International Nuclear Information System (INIS)

    Kurogi, T.; Linh, N. T. T.; Kuroki, T.; Yamada, T.; Hiraishi, A.

    2014-01-01

    Nitrification in biological wastewater treatment processes has been believed for long time to take place under neutral conditions and is inhibited under acidic conditions. However, we previously constructed acidophilic nitrifying sequencing-batch reactors (ANSBRs) being capable of nitrification at −1 was added. In all reactors, the pH varied between 2.7 and 4.0, and ammonium was completely converted to nitrate in every batch cycle. PCR-aided denaturing gradient gel electrophoresis (DGGE) targeting 16S rRNA genes revealed that some major clones assigned to TM7 bacteria and Gammaproteobacteria were constantly present during the overall period of operation. Fluorescence in situ hybridization (FISH) with specific oligonucleotide probes also showed that TM7 bacteria predominated in all SRAN reactors, accounting for 58% of the total bacterial population on average. Although the biological significance of the TM7 bacteria in the SRAN reactors are unknown, our results suggest that these bacteria are possibly streptomycin-resistant and play some important roles in the acidophilic nitrifying process

  4. Monte Carlo simulation of electron behavior in an electron cyclotron resonance microwave discharge sustained by circular TM11 mode fields

    International Nuclear Information System (INIS)

    Kuo, S.C.; Kuo, S.P.

    1996-01-01

    Electron behavior in an electron cyclotron resonance microwave discharge sustained by TM 11 mode fields of a cylindrical waveguide has been investigated via a Monte Carlo simulation. The time averaged, spatially dependent electron energy distribution is computed self-consistently. At low pressures (∼0.5 mTorr), the temperature of the tail portion of the electron energy distribution exceeds 40 eV, and the sheath potential is about -250 V. These results, which are about twice as high as the previous results for TM 01 mode fields [S. C. Kuo, E. E. Kunhardt, and S. P. Kuo, J. Appl. Phys. 73, 4197 (1993)], suggest that TM 11 mode fields have a stronger electron cyclotron resonance effect than TM 01 mode fields in a cylindrical waveguide. copyright 1996 American Institute of Physics

  5. Intracellular distribution of TM4SF1 and internalization of TM4SF1-antibody complex in vascular endothelial cells

    International Nuclear Information System (INIS)

    Sciuto, Tracey E.; Merley, Anne; Lin, Chi-Iou; Richardson, Douglas; Liu, Yu; Li, Dan; Dvorak, Ann M.; Dvorak, Harold F.; Jaminet, Shou-Ching S.

    2015-01-01

    Transmembrane-4 L-six family member-1 (TM4SF1) is a small plasma membrane-associated glycoprotein that is highly and selectively expressed on the plasma membranes of tumor cells, cultured endothelial cells, and, in vivo, on tumor-associated endothelium. Immunofluorescence microscopy also demonstrated TM4SF1 in cytoplasm and, tentatively, within nuclei. With monoclonal antibody 8G4, and the finer resolution afforded by immuno-nanogold transmission electron microscopy, we now demonstrate TM4SF1 in uncoated cytoplasmic vesicles, nuclear pores and nucleoplasm. Because of its prominent surface location on tumor cells and tumor-associated endothelium, TM4SF1 has potential as a dual therapeutic target using an antibody drug conjugate (ADC) approach. For ADC to be successful, antibodies reacting with cell surface antigens must be internalized for delivery of associated toxins to intracellular targets. We now report that 8G4 is efficiently taken up into cultured endothelial cells by uncoated vesicles in a dynamin-dependent, clathrin-independent manner. It is then transported along microtubules through the cytoplasm and passes through nuclear pores into the nucleus. These findings validate TM4SF1 as an attractive candidate for cancer therapy with antibody-bound toxins that have the capacity to react with either cytoplasmic or nuclear targets in tumor cells or tumor-associated vascular endothelium. - Highlights: • Anti-TM4SF1 antibody 8G4 was efficiently taken up by cultured endothelial cells. • TM4SF1–8G4 internalization is dynamin-dependent but clathrin-independent. • TM4SF1–8G4 complexes internalize along microtubules to reach the perinuclear region. • Internalized TM4SF1–8G4 complexes pass through nuclear pores into the nucleus. • TM4SF1 is an attractive candidate for ADC cancer therapy

  6. Intracellular distribution of TM4SF1 and internalization of TM4SF1-antibody complex in vascular endothelial cells

    Energy Technology Data Exchange (ETDEWEB)

    Sciuto, Tracey E.; Merley, Anne; Lin, Chi-Iou [Center for Vascular Biology Research and Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School (United States); Richardson, Douglas [Department of Molecular and Cellular Biology, Harvard University (United States); Liu, Yu [Department of Pharmacology, Shanxi Medical University, Xinjiannanlu 56, Shanxi Province, Taiyuan 030001 (China); Li, Dan; Dvorak, Ann M. [Center for Vascular Biology Research and Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School (United States); Dvorak, Harold F., E-mail: hdvorak@bidmc.harvard.edu [Center for Vascular Biology Research and Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School (United States); Jaminet, Shou-Ching S., E-mail: sjaminet@bidmc.harvard.edu [Center for Vascular Biology Research and Department of Pathology, Beth Israel Deaconess Medical Center and Harvard Medical School (United States)

    2015-09-25

    Transmembrane-4 L-six family member-1 (TM4SF1) is a small plasma membrane-associated glycoprotein that is highly and selectively expressed on the plasma membranes of tumor cells, cultured endothelial cells, and, in vivo, on tumor-associated endothelium. Immunofluorescence microscopy also demonstrated TM4SF1 in cytoplasm and, tentatively, within nuclei. With monoclonal antibody 8G4, and the finer resolution afforded by immuno-nanogold transmission electron microscopy, we now demonstrate TM4SF1 in uncoated cytoplasmic vesicles, nuclear pores and nucleoplasm. Because of its prominent surface location on tumor cells and tumor-associated endothelium, TM4SF1 has potential as a dual therapeutic target using an antibody drug conjugate (ADC) approach. For ADC to be successful, antibodies reacting with cell surface antigens must be internalized for delivery of associated toxins to intracellular targets. We now report that 8G4 is efficiently taken up into cultured endothelial cells by uncoated vesicles in a dynamin-dependent, clathrin-independent manner. It is then transported along microtubules through the cytoplasm and passes through nuclear pores into the nucleus. These findings validate TM4SF1 as an attractive candidate for cancer therapy with antibody-bound toxins that have the capacity to react with either cytoplasmic or nuclear targets in tumor cells or tumor-associated vascular endothelium. - Highlights: • Anti-TM4SF1 antibody 8G4 was efficiently taken up by cultured endothelial cells. • TM4SF1–8G4 internalization is dynamin-dependent but clathrin-independent. • TM4SF1–8G4 complexes internalize along microtubules to reach the perinuclear region. • Internalized TM4SF1–8G4 complexes pass through nuclear pores into the nucleus. • TM4SF1 is an attractive candidate for ADC cancer therapy.

  7. [Expression optimization and characterization of Tenebrio molitor antimicrobiol peptides TmAMP1m in Escherichia coli].

    Science.gov (United States)

    Alimu, Reyihanguli; Mao, Xinfang; Liu, Zhongyuan

    2013-06-01

    To improve the expression level of tmAMP1m gene from Tenebrio molitor in Escherichia coli, we studied the effects of expression level and activity of the fusion protein HIS-TmAMP1m by conditions, such as culture temperature, inducing time and the final concentration of inductor Isopropyl beta-D-thiogalactopyranoside (IPTG). We analyzed the optimum expression conditions by Tricine-SDS-PAGE electrophoresis, meanwhile, detected its antibacterial activity by using agarose cavity diffusion method. The results suggest that when inducing the recombinant plasmid with a final IPTG concentration of 0.1 mmol/L at 37 degrees C for 4 h, there was the highest expression level of fusion protein HIS-TmAMP1m in Escherichia coli. Under these conditions, the expression of fusion protein accounted for 40% of the total cell lysate with the best antibacterial activity. We purified the fusion protein HIS-TmAMPlm with nickel-nitrilotriacetic acid (Ni-NTA) metal-affinity chromatography matrices. Western blotting analysis indicates that the His monoclonal antibody could be specifically bound to fusion protein HIS-TmAMPlm. After expression by inducing, the fusion protein could inhibit the growth of host cell transformed by pET30a-tmAMP1m. The fusion protein HIS-TmAMP1m had better stability and remained higher antibacterial activities when incubated at 100 degrees C for 10 h, repeated freeze thawing at -20 degrees C, dissolved in strong acid and alkali, or treated by organic solvents and protease. Moreover, the minimum inhibitory concentration results demonstrated that the fusion protein HIS-TmAMP1m has a good antibacterial activity against Staphylococcus aureus, Staphylococcus sp., Corynebacterium glutamicum, Bacillus thuringiensis, Corynebacterium sp. This study laid the foundation to promote the application of insect antimicrobial peptides and further research.

  8. Family C 7TM receptor dimerization and activation

    DEFF Research Database (Denmark)

    Bonde, Marie Mi; Sheikh, Søren P; Hansen, Jakob Lerche

    2006-01-01

    The family C seven transmembrane (7TM) receptors constitutes a small and especially well characterized subfamily of the large 7TM receptor superfamily. Approximately 50% of current prescription drugs target 7TM receptors, this biologically important family represents the largest class of drug...... to be fully defined. This review presents the biochemical support for family C 7TM receptor dimerization and discusses its importance for receptor biosynthesis, surface expression, ligand binding and activation, since lessons learnt here may well be applicable to the whole superfamily of 7TM receptors.......-targets today. It is well established that family C 7TM receptors form homo- or hetero-dimers on the cell surface of living cells. The large extra-cellular domains (ECD) have been crystallized as a dimer in the presence and absence of agonist. Upon agonist binding, the dimeric ECD undergoes large conformational...

  9. A highly efficient Ho:YAG laser in-band pumped by a linewidth-narrowed Tm:YLF laser

    International Nuclear Information System (INIS)

    Duan, X M; Yang, C H; Yao, B Q; Wang, Y Z; Zhang, W S

    2013-01-01

    A highly efficient Tm:YLF-Ho:YAG laser system is presented in this paper. To obtain the narrow linewidth 1908 nm laser output, a volume Bragg grating combined with a Fabry–Perot (FP) etalon were used as wavelength selection devices. The maximum output power of 28.7 W was obtained with a slope efficiency of 42.3% in the Tm:YLF laser. An output wavelength of 1908.1 nm and FWHM linewidth of 60 pm were achieved at the maximum output level. Using this Tm:YLF laser as the pump source, high efficiency continuous wave and Q-switched operation of a Ho:YAG laser was demonstrated. Operating at continuous wave mode, up to 73.3% slope efficiency and 67.4% optical conversion efficiency were obtained in the Ho:YAG laser, corresponding to a diode-to-Ho optical conversion efficiency of 23.7%. For the Q-switched mode, when the incident Tm power was 27.3 W, the maximum single pulse energy of 3.4 mJ, pulse width of 15 ns and peak power of 229.3 kW were achieved at the pulse repetition rate of 5 kHz. The maximum average power of 18.3 W, pulse width of 18 ns and peak power of 103.6 kW were obtained at the pulse repetition rate of 10 kHz. (paper)

  10. Evaluation of NGAL TestTM on Cobas 6000

    DEFF Research Database (Denmark)

    Hansen, Young B L; Damgaard, Anette; Poulsen, Jørgen H

    2014-01-01

    BACKGROUND: Neutrophil Gelatinase-Associated Lipocalin (NGAL) is a promising biomarker for acute kidney injury (AKI). Our objectives were to evaluate the NGAL Test(TM) from Bioporto for both urine NGAL and plasma NGAL on the Cobas 6000 c501 (Roche Diagnostics, Rotkreuz, Switzerland) with matched...... measurements run on Hitachi 917, the method's linearity on the Cobas 6000 in urine, EDTA and Lithium-Heparin (Li-Hep), the influence of using EDTA or Li-Hep tubes and, finally, the impact of freezing and thawing on the sample. METHODS: Forty matched samples of Li-Hep and EDTA plasma and 40 urine samples were...

  11. Overview of Nintendo WiiTM use and potential applications for the Microsoft KinectTM in residential facilities

    NARCIS (Netherlands)

    C.A: Greenlay; H.R. Marston; J. van Hoof

    2013-01-01

    Marston, H.R., Greenlay, C.A., van Hoof, J. (2013) Overview of Nintendo WiiTM use and potential applications for the Microsoft KinectTM in residential facilities. Technology and Disability 25(2):77-85 doi: 10.3233/TAD-130369

  12. Functional Analysis of CD28/B7 and CD40/CD40L Costimulation During the in vivo Type 2 Immune Response

    Science.gov (United States)

    1995-10-06

    Fay, T.M., Masters, S.R, Laman , J.D., and Noelle, R.J. (1994b). The role of CD40 in the regulation ofhumoral and cell-mediated immunity. Immuno...1567-1575. 187 Foy, T.M., Laman , J.D., Ledbetter, J.A., Aruff’o, A., Claassen, E., and Noelle, R.J. (1994). gp39-CD40 interaction are essential for...cystine knot motif. Cell 73,421-424. Mohan, C., Shi, Y., Laman , J.D., and Datta, S.K. (1995). Interaction between CD40 and its ligand gp39 in the

  13. Stereotactic vacuum core biopsy of clustered microcalcifications classified as BI-RADS{sup TM} type 3; Stereotaktische Vakuumstanzbiopsie zur Abklaerung von gruppiertem Mikrokalk der Kategorie BI-RADS{sup TM} 3

    Energy Technology Data Exchange (ETDEWEB)

    Obenauer, S.; Fischer, U.; Baum, F.; Dammert, S.; Grabbe, E. [Goettingen Univ. (Germany). Abt. fuer Roentgendiagnostik; Fuezesi, L. [Goettingen Univ. (Germany). Zentrum Pathologie

    2001-08-01

    Purpose: Evaluation of stereotactic vacuum core biopsy of clustered microcalcifications categorized as BI-RADS{sup TM} 3. Material and methods: 86 patients with microcalcification BI-RADS{sup TM} 3 (probably benign, <3% malignant) underwent a stereotactic vacuum core biopsy (Mammotome, Fa. Ethicon Endo-Surgery Breast Care) using a digital stereotactic unit (Mammotest, Fa. Fischer Imaging). The removal of the calcifications was judged by two radiologists in consensus and classified as complete (100%), major (55-99%) or incomplete (<50%). Results: 4/86 patients could not be evaluated by vacuum core biopsy due to the localization of the microcalcifications close to the skin or lack of detection. In 40/82 cases a complete, in 38/82 a major, and in 4/82 an incomplete removal was achieved. Histology revealed 67 cases of fibrocystic changes, 4 papillomas, 4 fibroadenomas, 4 cases of atypical ductal hyperplasia (ADH), and 3 ductal carcinomas in situ (DCIS), one of these with a minimal-invasive tumor component. Patients with ADH were advised to undergo surgical biopsy. Histology revealed complete removal. 7 patients had complications or side-effects. Conclusions: Percutaneous vacuum core biopsy is a reliable minimal-invasive diagnostic method to come to the final diagnosis in patients with clustered microcalcifications categorized BI-RADS{sup TM} 3. However, if malignancy is proven (about 4% of our cases) an open biopsy is necessary. (orig.) [German] Zielsetzung: Evaluation der stereotaktischen Vakuumstanzbiopsie bei gruppierten Mikrokalzifikationen vom Typ BI-RADS{sup TM}3. Material und Methodik: Gruppiert angeordneter Mikrokalk der Kategorie BI-RADS{sup TM} 3 (wahrscheinlich benigne, <3% maligne) wurde bei 86 Patientinnen mit einer stereotaktischen Vakuumstanzbiopsie (Mammotome{sup circledR}, Fa. Ethicon Endo-Surgery Breast Care) an einem digitalen Stereotaxietisch (Mammotest, Fa. Fischer Imaging) abgeklaert. Das Ausmass der bioptisch entfernten Kalizifkationen wurde von

  14. Health-Related Quality of Life and Cognitive Functioning from the Perspective of Parents of School-Aged Children with Asperger's Syndrome Utilizing the PedsQL[TM

    Science.gov (United States)

    Limbers, Christine A.; Heffer, Robert W.; Varni, James W.

    2009-01-01

    HRQOL as a multidimensional construct has not been previously investigated in children with Asperger's Syndrome. The objective of the present study was to examine the initial feasibility, reliability, and validity of the PedsQL[TM] 4.0 Generic Core Scales and PedsQL[TM] Cognitive Functioning Scale parent proxy-report versions in school-aged…

  15. A Dual-Crystal Cavity Ho,Tm:GdVO4 Laser

    International Nuclear Information System (INIS)

    Zhu Guo-Li; Ju You-Lun; Yao Bao-Quan; Wang Yue-Zhu

    2012-01-01

    We report a 31.2 W cw diode-pumped cryogenic Ho(0.4at.%),Tm(4at.%):GdVO 4 laser in a dual-crystal cavity. The pumping sources are two fiber-coupled laser diodes with a fiber core diameter of 0.4 mm, both of which can supply 42 W near 802 nm. With an incident pump power of 70.3 W at 802.4 nm, a cw output power of 31.2 W at 2.05 μm is attained, corresponding to an optical-to-optical conversion efficiency of 44.4%. The M 2 factor is measured as ∼1.3 under an output power of 20 W. (fundamental areas of phenomenology(including applications))

  16. ScoutTM, a portable MCA system

    International Nuclear Information System (INIS)

    Cheng, A.Y.; Ziemba, F.P.; Browning, J.E.; Szluk, N.

    1998-01-01

    Quantrad Sensor's hand-held multichannel analyzer (MCA), the Scout TM , has evolved considerably from the initial licensing from Pacific Northwest Laboratories (operated by Battelle Memorial Institute for the U.S. DOE). The Scout TM has grown into a flexible MCA system with alpha-, gamma-, X-ray and neutron detection capabilities with wide ranging applications. The development philosophy is discussed along with specific examples of design choices in areas such as manufacturability, upgradability, probe interchangability and software user interface. Recently introduced products include: software enhancements, additional probes, customized software and a second generation instrument, the Scout512 TM , that boasts increased capabilities. Future developments are also discussed. (author)

  17. Ab initio structures and stabilities of HeTM3+ (TM=Sc-Cu)

    International Nuclear Information System (INIS)

    Wilson, David J.D.; Marsden, Colin J.; Nagy-Felsobuki, Ellak I. von

    2002-01-01

    The electronic structure and molecular properties of triply charged transition metal helides, HeTM 3+ (where TM = Sc-Cu), have been investigated employing CCSD(T), MCSCF and MRCI methods. Dissociation energies and harmonic vibrational frequencies have also been determined. For all the triply charged helides, the ground state is dominated by the 3d n electronic configuration. In addition, states with configurations that have holes in the metal 3d σ orbital exhibit greater binding energies. The suitability of single-reference methods and diagnostics for this series has been investigated, with the MCSCF wave function being the most reliable diagnostic tool for the applicability of SCF methods

  18. IHC-TM connect-disconnect and efferent control V.

    Science.gov (United States)

    Crane, H D

    1982-07-01

    Four previous papers in this series have explored how the idea of a set of disconnected inner hair cells (IHCs) that can "impact" the tectorial membrane (TM) is consistent with psychophysical data. This paper extends the model and explores the potential for mechanical interaction between the IHCs and outer hair cells (OHCs). In particular, it is speculated that the advantage of IHC-TM disconnect is extended dynamic range, and that movement of the movement of the OHCs and TM, under efferent control, constitutes a mechanical servo system for adjusting IHC-TM spacing along the cochlear partition to achieve this extended range.

  19. Affinity of 167Tm-citrate for tumor and liver tissue

    International Nuclear Information System (INIS)

    Ando, A.; Ando, I.; Hiraki, T.

    1983-01-01

    Strong affinity of 167 Tm-citrate for tumor tissue was reconfirmed by using Ehrlich tumor. Excellent tumor imaging was obtained with 167 Tm-citrate because of its strong tumor affinity and because of the suitable physical characteristics of 167 Tm. A large amount of 167 Tm had accumulated in the connective tissue which contained inflammatory tissue, quite large amounts were found in areas containing viable and necrotic tumor tissue, and small amounts were present in viable tumor tissue. 167 Tm was not seen in necrotic tumor tissue. It was concluded that lysosomes did not play a major role in the tumor concentration of 167 Tm, but played an important role in the liver concentration of this nuclide. In the case of hepatoma AH109A, it was presumed that lysosomes played a considerably important role in the tumor concentration of 167 Tm, hepatoma AH109A possessing some residual features of the liver. 167 Tm was bound to acid mucopolysaccharides and transposed by the acid mucopolysaccharides in the tumor tissues and liver. The acid mucopolysaccharides to which 167 Tm were bound in tumor and liver, were heparan sulfate, chondroitin sulfate (or keratosulfate) and heparin (or keratosulfate). (orig.)

  20. Efficient High Power Ho,Tm:GdVO4 Laser

    International Nuclear Information System (INIS)

    Wang Yue-Zhu; Zhu Guo-Li; Ju You-Lun; Yao Bao-Quan

    2011-01-01

    We report a 22.3 W cw diode-pumped cryogenic Ho(0.5at.%),Tm(at.5%):GdVO 4 laser at a wavelength of 2.05 μm. It is pumped by two fiber-coupled laser diodes with a fiber core diameter of 0.4 mm, both of which provide 42 W pump power near 802 nm. A cw output power of 22.3 W was obtained at the pump power of 51.0 W, corresponding to an optical-to-optical conversion efficiency of 43.7% when the ratio of the pump beam to oscillating laser beam in the crystal was ∼1.33:1. The M 2 factor was found to be 2.0 under an output power of 16.5 W. (fundamental areas of phenomenology(including applications))

  1. Comparative evaluation of two methods for 172Tm production in nuclear reactors

    International Nuclear Information System (INIS)

    Cohen, I.M.; Hayes, Alejandro; Melcer, Elsa

    2016-01-01

    A comparative evaluation of two methods for the production of 172 Tm in nuclear reactors is carried out. They are respectively based on two chains of double neutron capture reactions, 170 Er(n,γ) 171 Er(n,γ) 172 Er(β - ) 172 Tm and 170 Er(n,γ) 171 Er(β - ) 171 Tm(n,γ) 172 Tm, and a chain of triple neutron capture: 169 Tm(n,γ) 170 Tm(n,γ) 71 Tm(n,γ) 172 Tm. Theoretical considerations with respect to both ways of production are formulated and the mathematical equation are solved. Experiments of irradiation of Er 2 O 3 and Tm 2 O 3 were performed. Advantages and drawbacks of both methods are discussed. (author)

  2. Broadly tunable femtosecond mode-locking in a Tm:KYW laser near 2 μm.

    Science.gov (United States)

    Lagatsky, A A; Calvez, S; Gupta, J A; Kisel, V E; Kuleshov, N V; Brown, C T A; Dawson, M D; Sibbett, W

    2011-05-09

    Efficient mode-locking in a Tm:KY(WO(4))(2) laser is demonstrated by using InGaAsSb quantum-well SESAMs. Self-starting ultrashort pulse generation was realized in the 1979-2074 nm spectral region. Maximum average output power up to 411 mW was produced around 1986 nm with the corresponding pulse duration and repetition rate of 549 fs and 105 MHz respectively. Optimised pulse durations of 386 fs were produced with an average power of 235 mW at 2029 nm. © 2011 Optical Society of America

  3. Field applications of the ScoutTM portable MCA

    International Nuclear Information System (INIS)

    Cheng, A.Y.; Ziemba, F.P.; Browning, J.E.

    1998-01-01

    The use of Quantrad Sensor's Scout TM in field type applications is described. The portability of the Scout TM enables the user to obtain more accurate information in the field versus a survey meter. Isotopic identification is possible when ancillary information is combined with built-in software libraries. Data from the Scout TM in remediation at Stanford Linear Accelerator (SLAC), NORM (Naturally Occurring Radioactive Material) measurements in California's Central Valley oil fields, medical isotope identification at nuclear pharmaceutical company and emergency response applications are presented. Additionally, custom software enabled the use of the Scout TM in identification, qualification and detection of Special Nuclear Materials (SNM) in illicit trafficking and portal monitoring applications. (author)

  4. Sol–gel synthesis and photoluminescence studies on colour tuneable Dy3+/Tm3+ co-doped NaGd(WO4)2 phosphor for white light emission

    International Nuclear Information System (INIS)

    Durairajan, A.; Balaji, D.; Rasu, K. Kavi; Moorthy Babu, S.; Hayakawa, Y.; Valente, M.A.

    2015-01-01

    A series of Dy 3+ /Tm 3+ ion co-doped NaGd(WO 4 ) 2 (NGW) phosphors were synthesised by a sol–gel method at low temperature for white light emission. The structural and luminescence properties of the synthesised phosphors were studied by powder X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FT-IR), Raman and photoluminescence techniques. In Dy 3+ /Tm 3+ :NGW phosphors, the dopant ions substituted Gd 3+ ions that are located in S 4 sites of NGW host lattice. In NGW host, under UV excitation the Dy 3+ ions have shown strong yellow ( 4 F 9/2 → 6 H 13/2 ) and comparatively weak blue ( 4 F 9/2 → 6 H 15/2 ) emission transitions at 575 and 488 nm, respectively. Due to deficient blue colour the overall emission falls in yellow region. Hence, Tm 3+ ions having strong blue emission at 455 nm corresponding to the transition 1 D 2 → 3 F 4 were co-activated along with Dy 3+ ions in NGW matrix. By changing the doping concentrations of Tm 3+ and Dy 3+ ions in NGW, white light emission was tuned by 353 nm excitation wavelength. Their corresponding colour co-ordinates were calculated and found to be very close to the white colour chromaticity co-ordinates (0.333, 0.333). - Highlights: • Dy 3+ and Dy 3+ /Tm 3+ :NGW phosphors were synthesised by sol–gel methods. • The excitation spectrum confirmed the strong absorption in near-UV region. • The emission spectrum shows the yellow and white emission to doped and co-doped phosphors respectively. • The CIE co-ordinate conforms close to daylight emission

  5. Interplay between magnetic order at Mn and Tm sites alongside the structural distortion in multiferroic films of o -TmMn O3

    Science.gov (United States)

    Windsor, Y. W.; Ramakrishnan, M.; Rettig, L.; Alberca, A.; Bothschafter, E. M.; Staub, U.; Shimamoto, K.; Hu, Y.; Lippert, T.; Schneider, C. W.

    2015-06-01

    We employ resonant soft x-ray diffraction to individually study the magnetic ordering of the Mn and the Tm sublattices in single-crystalline films of orthorhombic (o -) TmMn O3 . The same magnetic ordering wave vector of (0 q 0 ) with q ≈0.46 is found for both ionic species, suggesting that the familiar antiferromagnetic order of the Mn ions induces a magnetic order on the Tm unpaired 4 f electrons. Indeed, intensity variations of magnetic reflections with temperature corroborate this scenario. Calculated magnetic fields at the Tm sites are used as a model magnetic structure for the Tm, which correctly predicts intensity variations at the Tm resonance upon azimuthal rotation of the sample. The model allows ruling out a b c -cycloid modulation of the Mn ions as the cause for the incommensurate ordering, as found in TbMn O3 . The structural distortion, which occurs in the ferroelectric phase below TC, was followed through nonresonant diffraction of structural reflections forbidden by the high-temperature crystal symmetry. The (0 q 0 ) magnetic reflection appears at the Mn resonance well above TC, indicating that this reflection is sensitive also to the intermediate sinusoidal magnetic phase. The model presented suggests that the Tm 4 f electrons are polarized well above the ferroelectric transition and are possibly not affected by the transition at TC. The successful description of the induced order observed at the Tm resonance is a promising example for future element-selective studies in which "spectator" ions may allow access to previously unobtainable information about other constituent ions.

  6. Relaxation phenomena and host exchange parameters in Tm van Vleck compounds

    International Nuclear Information System (INIS)

    Zevin, V.; Levin, R.; Shaltiel, D.; Baberschke, K.; Davidov, D.

    1977-01-01

    The ESR linewidth of Gd in TmP (measured by Sugawara et al (Phys. Rev.; B11 (1975)) TmSb and TmBi (measured in the present work and by Davidov and Baberschke (Phys. Lett.; A51:144 (1975)) exhibits an appreciable temperature dependence. This behaviour is attributed to the fluctuation spectra of the host Tm ions. The previous theory (Davidov et al (Phys. Rev.; B15:2771 (1977)) for impurity relaxation in weakly coupled van Vleck paramagnets based on the Bloch-Redfield kinetic equation is extended here and applied to the interpretation of the ESR linewidth in the Tm pnictides. In particular the second moment calculation of the host fluctuation spectra has been extended to include both pair correlation and autocorrelation contributions. Explicit expressions are given for Tm and Pr cubic van Vleck compounds. Using the crystalline field as extracted from independent neutron scattering techniques and the Gd-Tm exchange from the ESR g shift, the Tm-Tm host exchange has been estimated by fitting theory to the experimental results. The host exchange parameter in TmSb is very small confirming previous studies on this compound. (author)

  7. Investigations of LRE-HRE-TM thin films for hybrid recording

    Science.gov (United States)

    Li, Zuoyi; Cheng, Xiaomin; Jin, Fang; Li, Zhen; Lin, Gengqi; Yang, Xiaofei

    2005-09-01

    Light rare earth-heavy rare earth-transition metal (LRE-HRE-TM) thin films are a kind of important recording media. A lot of researches have been carried out on the LRE-HRE-TM thin films to improve its properties for data storage application and fruitful results have been achieved. This report gives a glance on the evolution of the research on LRE-HRE-TM recording media. At the same time, combined with the hybrid recording technology, some experimental results obtained on LRE-HRE-TM recording media are discussed, which suggest the promising prospect of the LRE-HRE-TM media in hybrid recording application.

  8. Analysis of n+165Ho and 169Tm reactions

    International Nuclear Information System (INIS)

    Young, P.G.; Arthur, E.D.; Philis, C.; Nagel, P.; Collin, M.

    1982-09-01

    Experimental data for neutron-induced reactions on 165 Ho and 169 Tm have been theoretically analyzed in preparation for calculations on the unstable isotopes of Tm. A set of deformed optical model parameters was determined from measurements of s- and p-wave neutron strength functions, total cross sections, elastic angular distributions, and 16-MeV proton scattering to the 165 Ho ground and first excited states. The parameters for the 165 Ho and 169 Tm nuclei were linked by means of an isospin term in the real and imaginary well depths, together with adjustment of the ν 2 and ν 4 deformation parameters based on systematics in this mass region. Transmission coefficients from this analysis were used in Hauser-Feshbach statistical model calculations of the 169 Tm(n,ν) cross section as well as the 169 Tm(n,2n) and (n,3n) cross sections to 23 MeV, after application of suitable preequilibrium corrections. The results of these calculations are in good agreement with most of the available experimental data on 165 Ho and 169 Tm

  9. ADAPT(tm trocar use for laparoscopic procedures in equidea

    Directory of Open Access Journals (Sweden)

    P.P.M. Teixeira

    2016-02-01

    Full Text Available O objetivo deste trabalho é descrever o uso do trocater modelo Adapt(tm no acesso laparoscópico em animais da família dos equídeos. O procedimento cirúrgico foi realizado em 15 equídeos (quatro jumentas, seis cavalos e cinco éguas, com peso médio de 320kg (290kg e 450kg, pesos máximo e mínimo, respectivamente. Os pacientes foram mantidos em posição quadrupedal, sob sedação e bloqueio local. Primeiramente, realizou-se o preparo asséptico, e o acesso foi feito pelo flanco direito ou pelo esquerdo, dependendo da estrutura a ser visualizada. Em todos os procedimentos, foi utilizado o trocater modelo Seal AdaptTM Ports (Teleflex Medical Introduces TautTM, USA, com diâmetro de 12mm. Inicialmente se fez uma incisão de pele de aproximadamente 15mm para inserção da ponta do trocater. Este foi inserido na ferida cirúrgica, realizando-se movimentos de 180º em sentido horário e anti-horário, até atingir a cavidade abdominal. Após esta etapa, o obturador do trocater foi retirado, e a ótica inserida para confirmar o acesso à cavidade abdominal. A síntese das camadas superficiais da muscular foi realizada com fio nylon nº 0, em um padrão Sultan, e posteriormente a dermorrafia, também com nylon nº 0, no padrão de Wolf. O equipamento apresentou eficiência nos procedimentos de dissecação das camadas subcutânea, musculares e peritônio, não ocorrendo significativa hemorragia nessas camadas. Em um paciente muar, ocorreu afastamento do peritônio parietal, e em alguns casos (40% ocorreu pequeno enfisema subcutâneo no pós-cirúrgico. Todos os pacientes apresentaram boa cicatrização da ferida cirúrgica. O trocater modelo AdaptTM mostrou-se eficiente na abordagem laparoscópica em equinos, apresentando segurança em se estabelecer o acesso e versatilidade no emprego de diversos instrumentais.

  10. Measurements of the 169Tm(n,2n)168Tm cross section between 9.0 and 17.5 MeV

    Science.gov (United States)

    Soter, J.; Bhike, Megha; Krishichayan, Fnu; Finch, S. W.; Tornow, W.

    2016-09-01

    Measurements of the 169Tm(n,2n)168Tm cross section have been performed in 0.5 MeV intervals for neutron energies ranging from 9.0 MeV to 17.5 MeV in order to resolve discrepancies in the current literature data. The neutron activation technique was used with 90Zr and 197Au as monitor foils. After irradiation, de-excitation gamma rays were recorded off-line with High-Purity Germanium (HPGE) detectors in TUNL's Low-Background Counting Facility. In addition, data for the 169Tm(n,3n)167Tm reaction have also been obtained from 15.5 MeV to 17.5 MeV. The results of these measurements provide the basis for investigating properties of the interial confinement fusion plasma in deuterium-tritium (DT) capsules at the National Ignition Facility located at Lawrence Livermore National Laboratory.

  11. Trapping processes in CaS:Eu2+,Tm3+

    International Nuclear Information System (INIS)

    Jia, Dongdong; Jia, Weiyi; Evans, D. R.; Dennis, W. M.; Liu, Huimin; Zhu, Jing; Yen, W. M.

    2000-01-01

    CaS:Eu 2+ ,Tm 3+ is a persistent red phosphor. Thermoluminescence was measured under different excitation and thermal treatment conditions. The results reveal that the charge defects, created by substituting Tm 3+ for Ca 2+ , serve as hole traps for the afterglow at room temperature. Tm 3+ plays the role of deep electron trapping centers, capturing electrons either through the conduction band or directly from the excited Eu 2+ ions. These two processes, in which two different sites of Tm 3+ are involved, correspond to two traps with different depths. (c) 2000 American Institute of Physics

  12. Monomeric Aβ(1-40) and Aβ(1-42) Peptides in Solution Adopt Very Similar Ramachandran Map Distributions That Closely Resemble Random Coil.

    Science.gov (United States)

    Roche, Julien; Shen, Yang; Lee, Jung Ho; Ying, Jinfa; Bax, Ad

    2016-02-09

    The pathogenesis of Alzheimer's disease is characterized by the aggregation and fibrillation of amyloid peptides Aβ(1-40) and Aβ(1-42) into amyloid plaques. Despite strong potential therapeutic interest, the structural pathways associated with the conversion of monomeric Aβ peptides into oligomeric species remain largely unknown. In particular, the higher aggregation propensity and associated toxicity of Aβ(1-42) compared to that of Aβ(1-40) are poorly understood. To explore in detail the structural propensity of the monomeric Aβ(1-40) and Aβ(1-42) peptides in solution, we recorded a large set of nuclear magnetic resonance (NMR) parameters, including chemical shifts, nuclear Overhauser effects (NOEs), and J couplings. Systematic comparisons show that at neutral pH the Aβ(1-40) and Aβ(1-42) peptides populate almost indistinguishable coil-like conformations. Nuclear Overhauser effect spectra collected at very high resolution remove assignment ambiguities and show no long-range NOE contacts. Six sets of backbone J couplings ((3)JHNHα, (3)JC'C', (3)JC'Hα, (1)JHαCα, (2)JNCα, and (1)JNCα) recorded for Aβ(1-40) were used as input for the recently developed MERA Ramachandran map analysis, yielding residue-specific backbone ϕ/ψ torsion angle distributions that closely resemble random coil distributions, the absence of a significantly elevated propensity for β-conformations in the C-terminal region of the peptide, and a small but distinct propensity for αL at K28. Our results suggest that the self-association of Aβ peptides into toxic oligomers is not driven by elevated propensities of the monomeric species to adopt β-strand-like conformations. Instead, the accelerated disappearance of Aβ NMR signals in D2O over H2O, particularly pronounced for Aβ(1-42), suggests that intermolecular interactions between the hydrophobic regions of the peptide dominate the aggregation process.

  13. In-beam gamma spectroscopy of 155Tm

    International Nuclear Information System (INIS)

    Raut, R.; Ganguly, S.; Kshetri, R.; Banerjee, P.; Bhattacharya, S.; Mukherjee, A.; Saha Sarkar, M.; Goswami, A.; Bhowal, S.; Ganguly, G.; Muralithar, S.; Singh, R.P.

    2005-01-01

    The observation of superdeformation in 154 Er has pronounced the possibility of observation of high spin phenomena in the neighbouring isotones. There has been a paucity of data on 155 Tm till day. The present work proposes to extend the level scheme of 155 Tm and thus established the systematics therein

  14. Measurements of nuclear polarization and nuclear magnetic moment of 170Tm in 170Tm:SrF2 by optical pumping

    International Nuclear Information System (INIS)

    Shimomura, K.

    1988-01-01

    Significant nuclear polarization of unstable 170 Tm in Tm 2+ :SrF 2 was for the first time achieved with β-ray radiation detected optical pumping in solids, providing a new powerful method to measure magnetic moments of unstable nuclei. (author)

  15. Stimulated Raman adiabatic passage in Tm3+:YAG

    International Nuclear Information System (INIS)

    Alexander, A. L.; Lauro, R.; Louchet, A.; Chaneliere, T.; Le Goueet, J. L.

    2008-01-01

    We report on the experimental demonstration of stimulated Raman adiabatic passage in a Tm 3+ :YAG crystal. Tm 3+ :YAG is a promising material for use in quantum information processing applications, but as yet there are few experimental investigations of coherent Raman processes in this material. We investigate the effect of inhomogeneous broadening and Rabi frequency on the transfer efficiency and the width of the two-photon spectrum. Simulations of the complete Tm 3+ :YAG system are presented along with the corresponding experimental results

  16. Affinity of /sup 167/Tm-citrate for tumor and liver tissue

    Energy Technology Data Exchange (ETDEWEB)

    Ando, A; Ando, I; Hiraki, T; Sakamoto, K; Hisada, K; Takeshita, M

    1983-10-07

    Strong affinity of /sup 167/Tm-citrate for tumor tissue was reconfirmed by using Ehrlich tumor. Excellent tumor imaging was obtained with /sup 167/Tm-citrate because of its strong tumor affinity and because of the suitable physical characteristics of /sup 167/Tm. A large amount of /sup 167/Tm had accumulated in the connective tissue which contained inflammatory tissue, quite large amounts were found in areas containing viable and necrotic tumor tissue, and small amounts were present in viable tumor tissue. /sup 167/Tm was not seen in necrotic tumor tissue. It was concluded that lysosomes did not play a major role in the tumor concentration of /sup 167/Tm, but played an important role in the liver concentration of this nuclide. In the case of hepatoma AH109A, it was presumed that lysosomes played a considerably important role in the tumor concentration of /sup 167/Tm, hepatoma AH109A possessing some residual features of the liver. /sup 167/Tm was bound to acid mucopolysaccharides and transposed by the acid mucopolysaccharides in the tumor tissues and liver. The acid mucopolysaccharides to which /sup 167/Tm were bound in tumor and liver, were heparan sulfate, chondroitin sulfate (or keratosulfate) and heparin (or keratosulfate).

  17. Powernext Day-AheadTM statistics April 30, 2005

    International Nuclear Information System (INIS)

    2005-04-01

    The introduction of a power exchange in France is a direct response to the opening up of the European electricity markets. Powernext SA is a Multilateral Trading Facility in charge of managing an optional and anonymous organised exchange offering: - Day-ahead contracts for the management of volume risk on Powernext Day-Ahead TM since 21 November 2001, - Medium term contracts for the management of price risk on Powernext Futures TM since 18 June 2004. This document presents in a series of tables and graphics the April 30, 2005 update of Powernext Day-Ahead TM statistics: traded volumes and average prices from November 2001 to April 2005, monthly overview from April 2004 to April 2005 (volumes, prices and price spreads), weekly overview from January to April 2005, daily and hourly overview and market resilience for April 2005, power consumption in March and April 2005 (average consumption, average forecasted consumption and average price on Powernext Day-Ahead TM ), power consumption on the French hub from January to April 2005 and Powernext Day-Ahead TM prices, transfer capacities in April 2005 (daily capacity allocations for France-Germany, France-Switzerland and France-Spain, daily and monthly capacity allocations for France-Belgium, auction on the France-UK Interconnector, daily and yearly capacity allocation for France-Italy), temperature variations in France from November 2004 to April 2005 and average prices on Powernext Day-Ahead TM , and balancing mechanism for March-April 2005 (half-hourly imbalance settlement prices). (J.S.)

  18. Powernext Day-AheadTM statistics - June 30, 2006

    International Nuclear Information System (INIS)

    2006-01-01

    The introduction of a power exchange in France is a direct response to the opening up of the European electricity markets. Powernext SA is a Multilateral Trading Facility in charge of managing an optional and anonymous organised exchange offering: - Day-ahead contracts for the management of volume risk on Powernext Day-Ahead TM since 21 November 2001, - Medium term contracts for the management of price risk on Powernext Futures TM since 18 June 2004. This document presents in a series of tables and graphics the June 30, 2006 update of Powernext Day-Ahead TM statistics: daily traded volumes and base-load prices from November 2001 to June 2006, monthly overview from June 2005 to June 2006 (volumes and prices), weekly overview from March to June 2006 (volumes and prices), daily and hourly overview and market resilience for June 2006, power consumption in May and June 2006 (average consumption, average forecasted consumption and average price on Powernext Day-Ahead TM ), power consumption on the French hub from July 2005 to May 2006 and Powernext Day-Ahead TM prices, transfer capacities in June 2006 (auction results for France-Germany, France-Belgium, France-UK, France-Spain and France-Italy, and daily capacity allocation for France-Switzerland), temperature variations in France from January 2005 to June 2006 and base-load Powernext Day-Ahead TM prices, and balancing mechanism for April, May and June 2006 (half-hourly imbalance settlement prices). (J.S.)

  19. Introduction program of M5TM cladding in Japan

    International Nuclear Information System (INIS)

    Mardon, Jean Paul; Kaneko, Nori

    2008-01-01

    Experience from irradiation in PWR has confirmed that M5 TM possesses all the properties required for upgraded operation including new fuel management approaches and high duty reactor operation. Specifically, the alloy M5 TM has demonstrated impressive improvements over Zircaloy-4 for fuel rod cladding and fuel assembly structural components. Moreover, several irradiation campaigns have been worldwide performed in order to confirm the excellent M5 TM in-pile behavior in very demanding PWR irradiation conditions (high void fraction, heat flux, temperature, lithium content and Zinc injection). Regarding licensing, the authorization for loading M5 TM alloy has been granted by US, UK, South Korean, German, Chinese, South-African, Swedish and Belgian Safety Authorities. Also the French Nuclear Safety Authority has given individually its authorization to load all-M5 TM fuel assembly batches in 1300MWe plants and a generic license to load all-M5 TM fuel in EDF N4 reactors and M5 TM fuel clad in 900MWe reactors for MOX parity fuel management. Licensing is also now underway in Switzerland, Finland, Brazil and Spain. The M5 TM alloy has demonstrated its superiority at burn-ups beyond current licensing limits, through operations in PWR at fuel rod burn-ups exceeding 71GWd/tU in the United States and 78GWd/tU in Europe. The Japanese nuclear industry has planned a stepwise approach to increase the burn-up of the fuel. Step-I fuel (48GWd/tU Fuel Assembly maximum burn-up) which was introduced in the late 80s. In the 90s started the licensing of the Step-II fuel (55GWd/tU Fuel Assembly maximum burn-up). Because the extension of the burn-up is important to reduce discharge fuel and cycle cost, the Japanese industry has plans to further extend the burn-up. In such burn-up region, fuel cladding with even better corrosion properties and very low hydrogen pick-up shall be necessary. M5 TM alloy, with high anticorrosion/hydriding properties, is suitable for not only the Step-II fuel

  20. Structural and electrical properties of TmTe under high pressure

    International Nuclear Information System (INIS)

    Tang, Jie; Matsumoto, Takehiko; Kosaka, Takayuki; Matsumura, Takeshi; Suzuki, Takashi; Mori, Nobuo

    1997-01-01

    Pressure-induced valence state of Tm ions in TmTe has been investigated by measurements of electrical resistivity in situ x-ray diffraction and magnetic susceptibility at high pressure. Below 2 GPa, the valence of Tm was confirmed to be 2 + from the results of compressibility and magnetic susceptibility. The pressure dependence of the electrical resistivity up to 2 GPa at room temperature showed an exponential decrease, indicating a linear closing of the energy gap at a rate of -1 meV/GPa. In the pressure range above 2 GPa where the energy gap disappeared, the valence transition from Tm 2+ to Tm 3+ was concluded from the pressure dependence of the lattice parameters. The electrical resistivity showing a logarithmic temperature dependence was reminiscent of Kondo effect. Above 6 GPa at which the pressure dependence of electrical resistivity abruptly decreased, the structure was confirmed to transform from the NaCl-type with Tm 3+ to a tetragonal structure. (author)

  1. Luminescence and scintillation enhancement of Y2O3:Tm transparent ceramic through post-fabrication thermal processing

    International Nuclear Information System (INIS)

    Chapman, M.G.; Marchewka, M.R.; Roberts, S.A.; Schmitt, J.M.; McMillen, C.; Kucera, C.J.; DeVol, T.A.; Ballato, J.; Jacobsohn, L.G.

    2015-01-01

    The effects of post-fabrication thermal processing in O 2 flux on the luminescence and scintillation of a Y 2 O 3 :Tm transparent ceramic were investigated. The results showed that the strategy of post-fabrication processing can be beneficial to the performance of the ceramics, depending on the cumulative processing time. After the first hour of processing, about 40% enhancement in the luminescence output together with about 20% enhancement in the scintillation light yield were obtained. The enhancements were tentatively assigned to the incorporation of oxygen into vacancy sites. Longer cumulative processing times lead to the incorporation of oxygen as interstitials that is detrimental to scintillation light yield but not to luminescence output. This work also revealed that thermoluminescence measurements are a useful tool to predict scintillation light yield of Y 2 O 3 :Tm. - Highlights: • Scintillation and PL enhancement of transparent ceramics through thermal processing. • First thermoluminescence measurements of Y 2 O 3 :Tm above room temperature. • Observation of correlation between TL and scintillation light yield results

  2. EEM{sup TM} wireless supervision

    Energy Technology Data Exchange (ETDEWEB)

    Bilic, H. [Ericsson-Nikola Tesla d.d. Zagreb (Croatia)

    2000-07-01

    By adding the GSM network to the communication level of Energy Management systems, energy operating centres (EOC) can offer wireless access to the supervised equipment. Furthermore EOC can profit from rapid service development in the GSM networks. With implementation of GPRS to the GSM network EOC can instantly offer wireless access to external IP based networks such as Internet and corporate Intranets. The author describes architecture and key characteristic of Ericsson EnergyMaster{sup TM} (EEM{sup TM}) system for Energy Management, how and where to implement wireless supervision, wireless access to IP addresses and also how to implement new services provided by the GSM network. (orig.)

  3. WebotsTM: Professional Mobile Robot Simulation

    Directory of Open Access Journals (Sweden)

    Olivier Michel

    2008-11-01

    Full Text Available Cyberbotics Ltd. develops WebotsTM, a mobile robotics simulation software that provides you with a rapid prototyping environment for modelling, programming and simulating mobile robots. The provided robot libraries enable you to transfer your control programs to several commercially available real mobile robots. WebotsTM lets you define and modify a complete mobile robotics setup, even several different robots sharing the same environment. For each object, you can define a number of properties, such as shape, color, texture, mass, friction, etc. You can equip each robot with a large number of available sensors and actuators. You can program these robots using your favorite development environment, simulate them and optionally transfer the resulting programs onto your real robots. WebotsTM has been developed in collaboration with the Swiss Federal Institute of Technology in Lausanne, thoroughly tested, well documented and continuously maintained for over 7 years. It is now the main commercial product available from Cyberbotics Ltd.

  4. Sealing ability of grar MTA AngelusTM, CPM TM and MBPc used as apical plugs

    Directory of Open Access Journals (Sweden)

    Fernando Accorsi Orosco

    2008-02-01

    Full Text Available This study evaluated the sealing ability of apical plugs fabricated with gray MTA AngelusTM sealer, CPM TM sealer and MBPc sealer. The root canals of 98 extracted single-rooted human teeth were instrumented with #5 to #1 Gates Glidden drills according to the crown-down technique until the #1 drill could pass through the apical foramen. The specimens were then prepared with K-files, starting with an ISO 50 until an ISO 90 could be visualized 1 mm beyond the apex. After root canal preparation, the external surface of each root was rendered impermeable and roots were assigned to 3 experimental groups (n = 30, which received a 5-mm thick apical plug of gray MTA AngelusTM, CPM TM and MBPc, and two control groups (n=4. The remaining portion of the canal in the experimental groups was filled by the lateral condensation technique. The teeth of each group, properly identified, were fixed on utility wax by their crowns and were placed in plastic flasks, leaving the apex free and facing upward. The flasks were filled with 0.2% Rhodamine B solution, pH 7.0, so as to completely cover the root apex of all teeth. The sealing ability was analyzed by measuring 0.2% Rhodamine B leakage after all groups had been maintained in this solution for 48 hours. Data were analyzed statistically by Kruskal-Wallis test and Dunn test with a=5%. The results showed that, among the tested materials used for fabrication of apical plugs, MBPc sealer had the least amount of leakage with statistically significant difference (p<0.05.

  5. Efficacy of OptiphosTM phytase on mineral digestibility in diets for breeding sows: effect during pregnancy an lactation

    NARCIS (Netherlands)

    Jongbloed, A.W.; Diepen, van J.T.M.; Binnendijk, G.P.; Bikker, P.; Vereecken, M.; Bierman, K.

    2013-01-01

    Phosphorus in most diets for breeding sows is digested for 20 to 40%, thus leading to a relatively high amount of P in the manure. To enhance the P digestibility in diets for both lactating and gestating sows, two separate experiments were carried out to study the efficacy of OptiphosTM phytase

  6. Tm-doped TiO2 and Tm2Ti2O7 pyrochlore nanoparticles: enhancing the photocatalytic activity of rutile with a pyrochlore phase.

    Science.gov (United States)

    De Los Santos, Desiré M; Navas, Javier; Aguilar, Teresa; Sánchez-Coronilla, Antonio; Fernández-Lorenzo, Concha; Alcántara, Rodrigo; Piñero, Jose Carlos; Blanco, Ginesa; Martín-Calleja, Joaquín

    2015-01-01

    Tm-doped TiO2 nanoparticles were synthesized using a water-controlled hydrolysis reaction. Analysis was performed in order to determine the influence of the dopant concentration and annealing temperature on the phase, crystallinity, and electronic and optical properties of the resulting material. Various characterization techniques were utilized such as X-ray diffraction, Raman spectroscopy, X-ray photoelectron spectroscopy and UV-vis spectroscopy. For the samples annealed at 773 and 973 K, anatase phase TiO2 was obtained, predominantly internally doped with Tm(3+). ICP-AES showed that a doping concentration of up to 5.8 atom % was obtained without reducing the crystallinity of the samples. The presence of Tm(3+) was confirmed by X-ray photoelectron spectroscopy and UV-vis spectroscopy: the incorporation of Tm(3+) was confirmed by the generation of new absorption bands that could be assigned to Tm(3+) transitions. Furthermore, when the samples were annealed at 1173 K, a pyrochlore phase (Tm2Ti2O7) mixed with TiO2 was obtained with a predominant rutile phase. The photodegradation of methylene blue showed that this pyrochlore phase enhanced the photocatalytic activity of the rutile phase.

  7. Power system reliability enhancement by using PowerformerTM

    Directory of Open Access Journals (Sweden)

    Rahmat-Allah Hooshmand

    2009-01-01

    Full Text Available A high-voltage generator PowerformerTM is a new generation of the AC generators. The most significant advantages of these PowerformerTM are their direct connection to high-voltage grid, higher availability, and more reactive power margin, short term overloading capacity and removing the power transformer from the structure of the power plant. In this paper, the installation effect of these generators on the power system reliability is investigated. The amount of the effects depends on the type and location of the power plant, location of the PowerformerTM, the size of load and network topology. For this purpose, in the 6-bus IEEE RBTS system, the conventional generators are replaced by these new PowerformerTM and then, the reliability indices are evaluated. The simulation results show that the reliability indices such as the expected duration of load curtailment (EDLC and the expected energy not served (EENS are improved. .

  8. MRI tracheomalacia (TM) assessment in pediatric patients

    DEFF Research Database (Denmark)

    Ciet, P.; Wielopolski, P.; Lever, S.

    Purpose: TM is an excessive narrowing of the intrathoracic part of the trachea. TM is a common congenital pediatric anomaly, but it’s often not recognized due to its unspecific clinical presentation. The aims of our study are: 1) to develop cine-MRI sequences to visualize central airways in static...... in pediatric population and allows avoiding radiation exposure and bronchoscopy for the evaluation of central airway dimensions....

  9. Red laser-diode pumped 806 nm Tm3+: ZBLAN fibre laser

    Science.gov (United States)

    Juárez-Hernández, M.; Mejía, E. B.

    2017-06-01

    A Tm3+-doped fluorozirconate (ZBLAN) fibre laser operating CW at 806 nm when diode-pumped at 687 nm is described for the first time. This device is based on the 3F4  →  3H6 transition, and is suitable for first telecom window and sensing applications. A slope efficiency of 50.3% and low threshold pump-power of 11.6 mW were obtained. Maximum output power of 15 mW for 40 mW coupled pump was achieved.

  10. Spectroscopic properties and energy transfer analysis of Tm3+-doped BaF2-Ga2O3-GeO2-La2O3 glass.

    Science.gov (United States)

    Yu, Shenglei; Yang, Zhongmin; Xu, Shanhui

    2010-05-01

    This paper reports on the spectroscopic properties and energy transfer analysis of Tm(3+)-doped BaF(2)-Ga(2)O(3)-GeO(2)-La(2)O(3) glasses with different Tm(2)O(3) doping concentrations (0.2, 0.5, 2.0, 2.5, 3.0, 3.5, 3.5, 4.0 wt%). Mid-IR fluorescence intensities in the range of 1,300 nm-2,200 nm have been measured when excited under an 808 nm LD for all the samples with the same pump power. Energy level structure and Judd-Ofelt parameters have been calculated based on the absorption spectra of Tm(3+), cross-relaxation rates and multi-phonon relaxation rates have been estimated with different Tm(2)O(3) doping concentrations. The maximum fluorescence intensity at around 1.8 mum has been obtained in Tm(2)O(3)-3 wt% sample and the maximum value of calculated stimulated emission cross-section of Tm(3+) in this sample is about 0.48 x 10(-20) cm(2) at 1,793 nm, and there is not any crystallization peak in the DSC curve of this sample, which indicate the potential utility of Tm(3+)-doped BaF(2)-Ga(2)O(3)-GeO(2)- La(2)O(3) glass for 2.0-microm optical fiber laser.

  11. Conserved water-mediated hydrogen bond network between TM-I, -II, -VI, and -VII in 7TM receptor activation

    DEFF Research Database (Denmark)

    Nygaard, Rie; Hansen, Louise Valentin; Mokrosinski, Jacek

    2010-01-01

    Five highly conserved polar residues connected by a number of structural water molecules together with two rotamer micro-switches, TrpVI:13 and TyrVII:20, constitute an extended hydrogen bond network between the intracellular segments of TM-I, -II, -VI, and -VII of 7TM receptors. Molecular dynamics...... to apparently function as a catching trap for water molecules. Mutational analysis of the beta2-adrenergic receptor demonstrated that the highly conserved polar residues of the hydrogen bond network were all important for receptor signaling but served different functions, some dampening constitutive activity...... (AsnI:18, AspII:10, and AsnVII:13), whereas others (AsnVII:12 and AsnVII:16) located one helical turn apart and sharing a water molecule were shown to be essential for agonist-induced signaling. It is concluded that the conserved water hydrogen bond network of 7TM receptors constitutes an extended...

  12. Study of yrast band in 155Tm

    International Nuclear Information System (INIS)

    Raut, R.; Bhowal, S.; Ganguly, S.; Kshetri, R.; Banerjee, P.; Bhattacharya, S.; Bhowmik, R.K.; Dasmahapatra, B.; Gangopadhyay, G.; Mukherjee, A.; Muralithar, S.; SahaSarkar, M.; Singh, R.P.; Goswami, A.

    2007-01-01

    The nucleus 155 Tm has been studied by a detailed in-beam gamma spectroscopy following the reaction 144 Sm( 14 N, 3n) 155 Tm, at a beam energy, E lab =70MeV, using a Compton suppressed gamma detector array. More than 25 new gamma transitions have been placed in the proposed scheme and the latter has been extended upto a spin-parity of (51/2 - ) at an excitation energy ∼ 6 MeV

  13. 42 CFR 460.42 - Suspension of enrollment or payment by CMS.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Suspension of enrollment or payment by CMS. 460.42... enrollment or payment by CMS. (a) Enrollment. If a PACE organization commits one or more violations specified in § 460.40, CMS may suspend enrollment of Medicare beneficiaries after the date CMS notifies the...

  14. HiPer-tex{sup TM} WindStrand{sup TM}: A new generation of high performance reinforcement

    Energy Technology Data Exchange (ETDEWEB)

    Peters, L.; Adolphs, G. [Owens Corning S and T, Battice (Belgium); Bech, J.I.; Broendsted, P. [Risoe National Lab., Material Research Dept., Roskilde (Denmark)

    2006-07-01

    Owens Corning has recently introduced the HiPer-texTM family of high performance reinforcements of which WindStrandTM is engineered to specific customer process requirements of resin infusion and prepregs for Wind Turbine blades manufacture. The new HiPer-tex technology platform enables up to 35% higher strength, 17% higher modulus, better impact, corrosion and high temperature resistance and significantly better fatigue properties versus traditional E Glass laminates. These attributes have been measured with various laminates types and are presented in this paper. These better performances are needed in markets such as Wind Energy, pressure vessels, armour, aerospace and light weight structural component. (au)

  15. Plastic Muscles TM as lightweight, low voltage actuators and sensors

    Science.gov (United States)

    Bennett, Matthew; Leo, Donald; Duncan, Andrew

    2008-03-01

    Using proprietary technology, Discover Technologies has developed ionomeric polymer transducers that are capable of long-term operation in air. These "Plastic Muscle TM" transducers are useful as soft distributed actuators and sensors and have a wide range of applications in the aerospace, robotics, automotive, electronics, and biomedical industries. Discover Technologies is developing novel fabrication methods that allow the Plastic Muscles TM to be manufactured on a commercial scale. The Plastic Muscle TM transducers are capable of generating more than 0.5% bending strain at a peak strain rate of over 0.1 %/s with a 3 V input. Because the Plastic Muscles TM use an ionic liquid as a replacement solvent for water, they are able to operate in air for long periods of time. Also, the Plastic Muscles TM do not exhibit the characteristic "back relaxation" phenomenon that is common in water-swollen devices. The elastic modulus of the Plastic Muscle TM transducers is estimated to be 200 MPa and the maximum generated stress is estimated to be 1 MPa. Based on these values, the maximum blocked force at the tip of a 6 mm wide, 35 mm long actuator is estimated to be 19 mN. Modeling of the step response with an exponential series reveals nonlinearity in the transducers' behavior.

  16. Optical Properties of Tm(3+) Ions in Alkali Germanate Glass

    Science.gov (United States)

    Walsh, Brian M.; Barnes, Norman P.; Reichle, Donald J.; Jiang, Shibin

    2006-01-01

    Tm-doped alkali germanate glass is investigated for use as a laser material. Spectroscopic investigations of bulk Tm-doped germanate glass are reported for the absorption, emission and luminescence decay. Tm:germanate shows promise as a fiber laser when pumped with 0.792 m diodes because of low phonon energies. Spectroscopic analysis indicates low nonradiative quenching and pulsed laser performance studies confirm this prediction by showing a quantum efficiency of 1.69.

  17. PLUS7TM In-Reactor Operating Performance and Economics

    International Nuclear Information System (INIS)

    Kim, Kyutae; Jang, Youngki; Choi, Joonhyung; Lee, Jinseok; Kim, Yoonho; Suh, Jungmin

    2006-01-01

    KNFC has developed an advanced fuel, PLUS7 TM , for the Korean Standard Nuclear Power Plants(KSNPs) through the joint development program with Westinghouse. With the help of various out-of-pile tests, it is found that the PLUS7 TM shows much better performance than the current fuel, GUARDIAN TM from the safety and economy points of view. Now four Lead Test Assembles(LTAs) of the PLUS7 TM are being irradiated for the 3 rd cycle after the successful completion of the 1 st and 2 nd irradiation cycles. During the 1 st and 2 nd irradiation cycles, no fuel failure was observed at LTAs and their nuclear-related parameters matched their design values well. During the overhaul period, on the other hand, pool side examinations were performed for four LTAs to generate key in-reactor fuel performance data such as fuel rod and assembly growths, fuel rod-to-top nozzle gap, fuel assembly bow and twist, fuel rod bow, spacer grid width, fuel rod diameter and fuel rod oxide layer thickness. It is found that all measured values are bounded by upper and lower predicted ones. The detailed economic analyses have shown that significant fuel cycle cost can be reduced by more than one million dollars per cycle of one KSNP with the introduction of the PLUS7 TM assembly. Furthermore, more than one hundred million dollars with power up-rating of 5% can be saved annually for currently operating eight KSNPs, which is easily and safety achievable with the PLUS7 TM assembly

  18. First principle investigation of structural, electronic and magnetic properties of cubic Cd{sub 0.9375}TM{sub 0.0625}S (TM=Ni, Co and Fe)

    Energy Technology Data Exchange (ETDEWEB)

    Yahi, Hakima, E-mail: yahihaki@yahoo.fr; Meddour, Athmane, E-mail: a_meddour@yahoo.fr

    2017-06-15

    In this study, we investigated the structural, electronic and magnetic properties of Cd{sub 0.9375}TM{sub 0.0625}S (TM=Ni, Co and Fe) compounds in zinc blende (B3) ferromagnetic phase using all-electron full-potential linear muffin tin orbital (FP-LMTO) calculations within the frame work of the density functional theory and the generalized gradient approximation. The analysis of electronic structures shows that Cd{sub 0.9375}Ni{sub 0.0625}S, Cd{sub 0.9375}Co{sub 0.0625}S and Cd{sub 0.9375}Fe{sub 0.0625}S compounds are half-metallic ferromagnets with 100% spin polarization at the Fermi level. This half-metallic behavior is confirmed by the total calculated magnetic moment per Ni, Co and Fe substituted transition metal (TM) atom, which is found to be 2 µ{sub B}, 3 µ{sub B} and 4 µ{sub B} for Cd{sub 0.9375}TM{sub 0.0625}S (TM=Ni, Co and Fe) compounds, respectively. Furthermore, we found that the TM-3d states are responsible for generating spin-polarization and magnetic moment in these compounds and we establish that the p-d hybridization reduces the local magnetic moment of TM atoms from its free space charge value and produces small local magnetic moments on nonmagnetic Cd and S host sites. Also, we predicted exchange splitting energy Δ{sub x}(pd) and exchange constants N{sub 0}α and N{sub 0}β. The calculated values validate the ferromagnetic nature of these compounds.

  19. Luminescence and scintillation enhancement of Y{sub 2}O{sub 3}:Tm transparent ceramic through post-fabrication thermal processing

    Energy Technology Data Exchange (ETDEWEB)

    Chapman, M.G.; Marchewka, M.R. [Department of Materials Science and Engineering, Clemson University, Clemson, SC 29634 (United States); Roberts, S.A.; Schmitt, J.M. [COMSET – Center for Optical Materials Science and Engineering Technologies, Clemson University, Anderson, SC 29625 (United States); McMillen, C. [Department of Chemistry, Clemson University, Clemson, SC 29634 (United States); Kucera, C.J. [COMSET – Center for Optical Materials Science and Engineering Technologies, Clemson University, Anderson, SC 29625 (United States); DeVol, T.A. [Environmental Engineering and Earth Sciences Department, Clemson University, Clemson, SC 29625 (United States); Ballato, J. [Department of Materials Science and Engineering, Clemson University, Clemson, SC 29634 (United States); COMSET – Center for Optical Materials Science and Engineering Technologies, Clemson University, Anderson, SC 29625 (United States); Jacobsohn, L.G., E-mail: luiz@clemson.edu [Department of Materials Science and Engineering, Clemson University, Clemson, SC 29634 (United States); COMSET – Center for Optical Materials Science and Engineering Technologies, Clemson University, Anderson, SC 29625 (United States)

    2015-09-15

    The effects of post-fabrication thermal processing in O{sub 2} flux on the luminescence and scintillation of a Y{sub 2}O{sub 3}:Tm transparent ceramic were investigated. The results showed that the strategy of post-fabrication processing can be beneficial to the performance of the ceramics, depending on the cumulative processing time. After the first hour of processing, about 40% enhancement in the luminescence output together with about 20% enhancement in the scintillation light yield were obtained. The enhancements were tentatively assigned to the incorporation of oxygen into vacancy sites. Longer cumulative processing times lead to the incorporation of oxygen as interstitials that is detrimental to scintillation light yield but not to luminescence output. This work also revealed that thermoluminescence measurements are a useful tool to predict scintillation light yield of Y{sub 2}O{sub 3}:Tm. - Highlights: • Scintillation and PL enhancement of transparent ceramics through thermal processing. • First thermoluminescence measurements of Y{sub 2}O{sub 3}:Tm above room temperature. • Observation of correlation between TL and scintillation light yield results.

  20. Crystal growth, spectroscopic and laser properties of Tm:LuAG crystal

    Science.gov (United States)

    Xu, X. D.; Wang, X. D.; Lin, Z. F.; Cheng, Y.; Li, D. Z.; Cheng, S. S.; Wu, F.; Zhao, Z. W.; Gao, C. Q.; Gao, M. W.; Xu, J.

    2009-11-01

    Tm:Lu3Al5O12 (Tm:LuAG) crystal was grown by the Czochralski method. The segregation coefficient was measured by Inductively Coupled Plasma Atomic Emission Spectrometer. The cell parameters were analyzed with X-ray powder diffraction experiments. The absorption and fluorescence spectra of Tm:LuAG crystal at room temperature were investigated. With a 20 W fiber-coupled diode laser as pump source, the continuous-wave (CW) laser action of Tm:LuAG crystal was demonstrated. The maximum output power at 2020 nm was obtained to be 3.04 W, and the slope efficiency was 25.3%.

  1. Diode-Pumped Thulium (Tm)/Holmium (Ho) Composite Fiber 2.1-Micrometers Laser

    Science.gov (United States)

    2015-09-01

    Schematic of the 800-nm diode pumped Tm/Ho composite fiber laser 8 Under quasi-continuous wave (Q- CW ) pumping conditions of 1-ms duration and a...Fig. 9 (Top) Schematic of the 800-nm diode -pumped Tm/Ho composite fiber laser with outcoupler. (Left) Q- CW laser performance of the Tm/Ho composite...ARL-TR-7452 ● SEP 2015 US Army Research Laboratory Diode -Pumped Thulium (Tm)/Holmium (Ho) Composite Fiber 2.1-μm Laser by G

  2. Methodology for Developing the REScheckTM Software through Version 4.2

    Energy Technology Data Exchange (ETDEWEB)

    Bartlett, Rosemarie [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Connell, Linda M. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Gowri, Krishnan [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Lucas, R. G. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Schultz, Robert W. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Taylor, Zachary T. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Wiberg, John D. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2009-08-01

    This report explains the methodology used to develop Version 4.2 of the REScheck software developed for the 1992, 1993, and 1995 editions of the MEC, and the 1998, 2000, 2003, and 2006 editions of the IECC, and the 2006 edition of the International Residential Code (IRC). Although some requirements contained in these codes have changed, the methodology used to develop the REScheck software for these five editions is similar. REScheck assists builders in meeting the most complicated part of the code-the building envelope Uo-, U-, and R-value requirements in Section 502 of the code. This document details the calculations and assumptions underlying the treatment of the code requirements in REScheck, with a major emphasis on the building envelope requirements.

  3. TmCd quadrupolar ordering and magnetic interactions

    International Nuclear Information System (INIS)

    Aleonard, R.; Morin, P.

    1979-01-01

    The paramagnetic compound TmCd crystallizes with the CsCl-type structure. Its Jahn-Teller behavior was first observed by Luethi and coworkers. We analyze here various physical properties with a pure-harmonic-elasticity model. The structural transition between cubic and tetragonal phases is now fully described (first-order character and temperature of occurrence) as well as the magnetic susceptibility, magnetization process, specific-heat, elastic-constant, and strain data. The relevant Hamiltonian takes into account the second-order magnetoelastic coupling and the quadrupolar exchange in addition to the cubic crystal field and the Heisenberg bilinear interactions. TmCd appears to be closely related to isomorphous TmZn and completes the illustration of the competition between bilinear and quadrupolar interactions occurring in some rare-earth intermetallics. In these two compounds, the quadrupolar exchange is many times stronger than the magnetoelastic coupling and the quadrupolar ordering then drives the structural transition. This situation is opposite to that occurring in (actual) Jahn-Teller compounds

  4. Powernext FuturesTM statistics. April 30, 2006

    International Nuclear Information System (INIS)

    2006-01-01

    The introduction of a power exchange in France is a direct response to the opening up of the European electricity markets. Powernext SA is a Multilateral Trading Facility in charge of managing an optional and anonymous organised exchange offering: - Day-ahead contracts for the management of volume risk on Powernext Day-Ahead TM since 21 November 2001, - Medium term contracts for the management of price risk on Powernext Futures TM since 18 June 2004. This document presents in a series of tables and graphics the April 30, 2006 update of Powernext Futures TM statistics: year, quarter and month contracts for April 2006, base-load and peak-load contracts overview from November 2005 to April 2006 (monthly volume in MW, open interest by delivery year in MWh, daily settlement price of the upcoming delivery period), and market liquidity in April 2006 (average bid ask spread and availability for base-load and peak-load contracts). (J.S.)

  5. Powernext FuturesTM statistics. Jun 30, 2006

    International Nuclear Information System (INIS)

    2006-01-01

    The introduction of a power exchange in France is a direct response to the opening up of the European electricity markets. Powernext SA is a Multilateral Trading Facility in charge of managing an optional and anonymous organised exchange offering: - Day-ahead contracts for the management of volume risk on Powernext Day-Ahead TM since 21 November 2001, - Medium term contracts for the management of price risk on Powernext Futures TM since 18 June 2004. This document presents in a series of tables and graphics the June 30, 2006 update of Powernext Futures TM statistics: year, quarter and month contracts for June 2006, base-load and peak-load contracts overview from January 2006 to June 2006 (monthly volume in MW, open interest by delivery year in MWh, daily settlement price of the upcoming delivery period), and market liquidity in June 2006 (average bid ask spread and availability for base-load and peak-load contracts). (J.S.)

  6. The role of charge transfer in the oxidation state change of Ce atoms in the TM13-CeO2(111) systems (TM = Pd, Ag, Pt, Au): a DFT + U investigation.

    Science.gov (United States)

    Tereshchuk, Polina; Freire, Rafael L H; Ungureanu, Crina G; Seminovski, Yohanna; Kiejna, Adam; Da Silva, Juarez L F

    2015-05-28

    Despite extensive studies of transition metal (TM) clusters supported on ceria (CeO2), fundamental issues such as the role of the TM atoms in the change in the oxidation state of Ce atoms are still not well understood. In this work, we report a theoretical investigation based on static and ab initio molecular dynamics density functional theory calculations of the interaction of 13-atom TM clusters (TM = Pd, Ag, Pt, Au) with the unreduced CeO2(111) surface represented by a large surface unit cell and employing Hubbard corrections for the strong on-site Coulomb correlation in the Ce f-electrons. We found that the TM13 clusters form pyramidal-like structures on CeO2(111) in the lowest energy configurations with the following stacking sequence, TM/TM4/TM8/CeO2(111), while TM13 adopts two-dimensional structures at high energy structures. TM13 induces a change in the oxidation state of few Ce atoms (3 of 16) located in the topmost Ce layer from Ce(IV) (itinerant Ce f-states) to Ce(III) (localized Ce f-states). There is a charge flow from the TM atoms to the CeO2(111) surface, which can be explained by the electronegativity difference between the TM (Pd, Ag, Pt, Au) and O atoms, however, the charge is not uniformly distributed on the topmost O layer due to the pressure induced by the TM13 clusters on the underlying O ions, which yields a decrease in the ionic charge of the O ions located below the cluster and an increase in the remaining O ions. Due to the charge flow mainly from the TM8-layer to the topmost O-layer, the charge cannot flow from the Ce(IV) atoms to the O atoms with the same magnitude as in the clean CeO2(111) surface. Consequently, the effective cationic charge decreases mainly for the Ce atoms that have a bond with the O atoms not located below the cluster, and hence, those Ce atoms change their oxidation state from IV to III. This increases the size of the Ce(III) compared with the Ce(IV) cations, which builds-in a strain within the topmost Ce layer, and

  7. In vitro screening of reversible and time-dependent inhibition on CYP3A by TM208 and TM209 in rat liver microsomes

    Directory of Open Access Journals (Sweden)

    Miaoran Ning

    2012-04-01

    Full Text Available TM208 and TM209, dithiocarbamate derivatives with potential anti-cancer effects, were evaluated in reversible and time-dependent cytochrome P450 (CYP 3A inhibition assays in rat liver microsomes using testosterone as probe substrate. Both compounds were found to be weak reversible inhibitors and moderate mechanism-based inhibitors of rat CYP3A. For reversible inhibition on rat CYP3A, the Ki values of competitive inhibition model were 12.10±1.75 and 13.94±1.31 μM, respectively. For time-dependent inhibition, the inactivation constants (Kl were 31.93±12.64 and 32.91±15.58 μM, respectively, and the maximum inactivation rates (kinact were 0.03497±0.0069 and 0.07259±0.0172 min−1 respectively. These findings would provide useful in vitro information for future in vivo DDI studies on TM208 or TM209.

  8. Randomized controlled clinical trial of long-term chemo-mechanical caries removal using PapacarieTM gel

    Directory of Open Access Journals (Sweden)

    Lara Jansiski MOTTA

    2014-07-01

    Full Text Available Objectives: Compare the effectiveness of PapacarieTM gel for the chemo-mechanical removal of carious lesions on primary teeth to conventional caries removal with a low-speed bur with regard to execution time, clinical aspects and radiographic findings. Material and Methods: A randomized controlled clinical trial with a split-mouth design was carried out. The sample was composed of 20 children aged four to seven years, in whom 40 deciduous teeth were randomly divided into two groups: chemo-mechanical caries removal with PapacarieTM and removal of carious dentin with a low-speed bur. Each child underwent both procedures and served as his/her own control. Restorations were performed with glass ionomer cement. The time required to perform the procedure was also analyzed. The patients underwent longitudinal clinical and radiographic follow-up of the restorations. Results: No statistically significant difference between groups was found regarding the time required to perform the procedures and the radiographic follow up. Statistically significant differences between groups were found in the clinical evaluation at 6 and 18 months after treatment. Conclusion: PapacarieTM is as effective as the traditional method for the removal of carious dentin on deciduous teeth, but offers the advantages of the preservation of sound dental tissue as well as the avoidance of sharp rotary instruments and local anesthesia.

  9. Study of electroless nickel plating on PerFactoryTM rapid prototype model

    OpenAIRE

    J.C. Rajaguru; C. Au, M. Duke

    2012-01-01

    This paper presents an investigation of electroless nickel plating on PerFactoryTM rapid prototype model built on PerFactoryTM R05 material. PerFactoryTM R05 is acrylic based photo sensitive resin. It is a popular material in rapid prototyping using PerFactoryTM method which employs addictive manufacturing technique to build prototypes for visual inspection, assembly etc. Metallization of such a prototype can extend the application envelop of the rapid prototyping technique as they can be use...

  10. Identifying Tm-C82 isomers with density functional theory calculations

    International Nuclear Information System (INIS)

    Zheng Limin; He Hongqing; Yang Minghui; Zeng Qun; Yang Mingli

    2010-01-01

    Density functional theory calculations have been performed to study the geometrical and electronic properties of endohedral metallofullerene Tm-C 82 isomers. Three energetically favorable isomers (with C s , C 2 and C 2v symmetry, respectively) are identified which are consistent with the nuclear magnetic resonance (NMR) observations. The simulated ultraviolet photoelectron spectra (UPS) based on the three structures agree well with the measurements. Particularly, the parent cage of the experimentally observed Tm-C 82 isomer with C s symmetry is newly assigned, which matches the experiments better than early assignments. In addition, strong interaction between an endohedral Tm atom and the C 82 cage is discussed and is thought to be responsible for the dramatic change in the relative stability of C 82 isomers when Tm is encapsulated.

  11. Monomeric Aβ1–40 and Aβ1–42 Peptides in Solution Adopt Very Similar Ramachandran Map Distributions That Closely Resemble Random Coil

    Science.gov (United States)

    2016-01-01

    The pathogenesis of Alzheimer’s disease is characterized by the aggregation and fibrillation of amyloid peptides Aβ1–40 and Aβ1–42 into amyloid plaques. Despite strong potential therapeutic interest, the structural pathways associated with the conversion of monomeric Aβ peptides into oligomeric species remain largely unknown. In particular, the higher aggregation propensity and associated toxicity of Aβ1–42 compared to that of Aβ1–40 are poorly understood. To explore in detail the structural propensity of the monomeric Aβ1–40 and Aβ1–42 peptides in solution, we recorded a large set of nuclear magnetic resonance (NMR) parameters, including chemical shifts, nuclear Overhauser effects (NOEs), and J couplings. Systematic comparisons show that at neutral pH the Aβ1–40 and Aβ1–42 peptides populate almost indistinguishable coil-like conformations. Nuclear Overhauser effect spectra collected at very high resolution remove assignment ambiguities and show no long-range NOE contacts. Six sets of backbone J couplings (3JHNHα, 3JC′C′, 3JC′Hα, 1JHαCα, 2JNCα, and 1JNCα) recorded for Aβ1–40 were used as input for the recently developed MERA Ramachandran map analysis, yielding residue-specific backbone ϕ/ψ torsion angle distributions that closely resemble random coil distributions, the absence of a significantly elevated propensity for β-conformations in the C-terminal region of the peptide, and a small but distinct propensity for αL at K28. Our results suggest that the self-association of Aβ peptides into toxic oligomers is not driven by elevated propensities of the monomeric species to adopt β-strand-like conformations. Instead, the accelerated disappearance of Aβ NMR signals in D2O over H2O, particularly pronounced for Aβ1–42, suggests that intermolecular interactions between the hydrophobic regions of the peptide dominate the aggregation process. PMID:26780756

  12. Listening and Legos[TM

    Science.gov (United States)

    Morris, Pamela

    2012-01-01

    This simple exercise, performed in teams, gives students practice in listening to instructions, particularly when there are restrictions for the communication. The teams compete in a limited amount of time to build a Lego[TM] structure based on the instructions of one team member. Which team listens the best and is most successful?

  13. NaGd(MoO4)2 nanocrystals with diverse morphologies: controlled synthesis, growth mechanism, photoluminescence and thermometric properties.

    Science.gov (United States)

    Li, Anming; Xu, Dekang; Lin, Hao; Yang, Shenghong; Shao, Yuanzhi; Zhang, Yueli

    2016-08-10

    Pure tetragonal phase, uniform and well-crystallized sodium gadolinium molybdate (NaGd(MoO4)2) nanocrystals with diverse morphologies, e.g. nanocylinders, nanocubes and square nanoplates have been selectively synthesized via oleic acid-mediated hydrothermal method. The phase, structure, morphology and composition of the as-synthesized products are studied. Contents of both sodium molybdate and oleic acid of the precursor solutions are found to affect the morphologies of the products significantly, and oleic acid plays a key role in the morphology-controlled synthesis of NaGd(MoO4)2 nanocrystals with diverse morphologies. Growth mechanism of NaGd(MoO4)2 nanocrystals is proposed based on time-dependent morphology evolution and X-ray diffraction analysis. Morphology-dependent down-shifting photoluminescence properties of NaGd(MoO4)2: Eu(3+) nanocrystals, and upconversion photoluminescence properties of NaGd(MoO4)2: Yb(3+)/Er(3+) and Yb(3+)/Tm(3+) nanoplates are investigated in detail. Charge transfer band in the down-shifting excitation spectra shows a slight blue-shift, and the luminescence intensities and lifetimes of Eu(3+) are decreased gradually with the morphology of the nanocrystals varying from nanocubes to thin square nanoplates. Upconversion energy transfer mechanisms of NaGd(MoO4)2: Yb(3+)/Er(3+), Yb(3+)/Tm(3+) nanoplates are proposed based on the energy level scheme and power dependence of upconversion emissions. Thermometric properties of NaGd(MoO4)2: Yb(3+)/Er(3+) nanoplates are investigated, and the maximum sensitivity is determined to be 0.01333 K(-1) at 285 K.

  14. Full Immersive Virtual Environment Cave[TM] in Chemistry Education

    Science.gov (United States)

    Limniou, M.; Roberts, D.; Papadopoulos, N.

    2008-01-01

    By comparing two-dimensional (2D) chemical animations designed for computer's desktop with three-dimensional (3D) chemical animations designed for the full immersive virtual reality environment CAVE[TM] we studied how virtual reality environments could raise student's interest and motivation for learning. By using the 3ds max[TM], we can visualize…

  15. Improving the photoluminescence response of Er-Tm: Al2O3 films by Yb codoping

    International Nuclear Information System (INIS)

    Xiao Zhisong; Serna, R.; Afonso, C.N.; Cheng Guoan; Vickridge, I.

    2007-01-01

    Amorphous Al 2 O 3 films doped with Er, Tm and Yb have been prepared by pulsed laser deposition. A broadband emission in the range 1400-1700 nm with two peaks around 1540 and 1640 nm has been observed, both in the Er-Tm and Er-Tm-Yb codoped films. The Tm-related photoluminescence (PL) intensity at 1640 nm is enhanced when codoping with Yb thus suggesting the existence of multiple energy transfer processes from Yb to Er and Er to Tm. The Er-Tm-Yb codoped film exhibits a broadband emission with a full-width half-maximum of 184 nm similar to that of the film codoped with Tm and Er but having higher Tm to Er concentration ratio and higher PL lifetime values

  16. Equation of states and phonons at high pressure of intermediate valence compound TmTe

    International Nuclear Information System (INIS)

    Jha, Prafulla K.; Sanyal, Sankar P.

    1997-01-01

    The study of equation of states and pressure dependence of the phonon frequencies of the compound TmTe have been performed by using a simple interatomic potential approach in the frame work of rigid ion model. The compressibility study confirms that below 2 GPa the valence of the Tm is 2+ while there is a valence transition from Tm 2+ to Tm 3+ above 2 GPa. The phonon frequencies of TmTe increases as pressure is increased. (author)

  17. Scintillation characteristics of Tm3+ in Ca3(BO3)2 crystals

    International Nuclear Information System (INIS)

    Fujimoto, Yutaka; Yanagida, Takayuki; Yokota, Yuui; Kawaguchi, Noriaki; Fukuda, Kentaro; Totsuka, Daisuke; Watanabe, Kenichi; Yamazaki, Atsushi; Yoshikawa, Akira

    2011-01-01

    Basic optical properties and radiation responses of undoped, Tm 3+ 1.0% and 2.0% activated Ca 3 (BO 3 ) 2 (CBO) crystalline scintillator prepared by the micro-pulling down (μ-PD) method are reported. Tm 3+ : CBO crystals showed three weak absorption bands around 190, 260 and 350 nm, owing to the Tm 3+ 4f–4f transition. Strong blue luminescence peaks at 360 and 460 nm which are ascribed to the 1 D 2 – 3 H 6 and 1 D 2 – 3 F 4 transitions of Tm 3+ respectively were observed under 241 Am 5.5 MeV α-ray excitation. The scintillation light yield of 2.0% Tm 3+ -doped CBO crystal was evaluated to be about 250 ph/n from the 252 Cf excited pulse height spectrum.

  18. TM-pass polarizer based on multilayer graphene polymer waveguide

    Science.gov (United States)

    Cai, Ke-su; Li, Yue-e.; Wei, Wen-jing; Mu, Xi-jiao; Ma, A.-ning; Wang, Zhong; Song, Dan-ming

    2018-05-01

    A TM-pass polarizer based on multilayer graphene polymer waveguide is proposed and theoretically analyzed. The mode properties, the extinction ratio, the insertion loss and the bandwidth are also discussed. The results show that a TM-pass polarizer, which only guides the TM mode, can be achieved by multilayer graphene polymer waveguide. With length of 150 μm, the proposed polarizer can achieve extinction ratio of 33 dB and insertion loss of 0.5 dB at optical wavelength of 1.55 μm. This device has an excellent performance, including large extinction ratio and low insertion loss within the spectral range from 1.45 μm to 1.6 μm.

  19. Inner bremsstrahlung accompanying beta decay of 170Tm

    International Nuclear Information System (INIS)

    Sanjeeviah, H.; Venkataramaiah, P.; Gundu Rao, K.S.

    1980-01-01

    The inner bremmsstrahlung (IB) spectrum accompanying beta decay of 170 Tm was measured using magnetic deflection technique. The raw spectrum was unfolded using the procedure of Liden and Starfelt. The unfolded IB spectrum was compared with the theories of Knipp and Uhlenbeck and Bloch; Lewis and Ford. Comparison was made with Ford and Martin theory in order to estimate the contribution of detour transitions to the IB spectrum of 170 Tm. (author)

  20. Preparation and characterization of micro-arc-induced Pd/TM(TM = Ni, Co and Ti) catalysts and comparison of their electrocatalytic activities toward ethanol oxidation

    International Nuclear Information System (INIS)

    Wang, Xiaoguang; Ma, Guanshui; Zhu, Fuchun; Lin, Naiming; Tang, Bin; Zhang, Zhonghua

    2013-01-01

    Using the electro-spark deposition technique, a novel kind of Pd/TM (TM = Ni, Co and Ti) electrode was successfully prepared by arc-depositing Pd on the transition metal substrates. The structure, morphology and chemical composition of the arc-deposited films were investigated using thin-film X-ray diffraction (TF-XRD), scanning electron microscopy (SEM) and energy dispersive X-ray analysis (EDX). The results show that, a coarsening topographical morphology can be obtained, being composed of numerous craters/spots with sizes ranging from nano-scales to several microns. The electrochemical measurements indicate that the arc-deposited Pd/TM electrodes exhibit distinct electrochemical behaviors and the catalytic activity toward ethanol electro-oxidation reaction (EOR) is highly dependent upon the nature of substrate. Among the Pd/TM electrodes investigated, the arc-deposited Pd/Co reveals the best activity and superior poisoning tolerance towards ethanol oxidation and will find promising applications as a candidate for the anode catalyst of direct ethanol fuel cells (DEFCs)

  1. Data fusion of Landsat TM and IRS images in forest classification

    Science.gov (United States)

    Guangxing Wang; Markus Holopainen; Eero Lukkarinen

    2000-01-01

    Data fusion of Landsat TM images and Indian Remote Sensing satellite panchromatic image (IRS-1C PAN) was studied and compared to the use of TM or IRS image only. The aim was to combine the high spatial resolution of IRS-1C PAN to the high spectral resolution of Landsat TM images using a data fusion algorithm. The ground truth of the study was based on a sample of 1,020...

  2. Comparative Spectroscopic Investigation of Tm3+:Tellurite Glasses for 2-μm Lasing Applications

    Directory of Open Access Journals (Sweden)

    Huseyin Cankaya

    2018-02-01

    Full Text Available We performed a comparative spectroscopic analysis on three novel Tm3+:tellurite-based glasses with the following compositions Tm2O3:TeO2-ZnO (TeZnTm, Tm2O3:TeO2-Nb2O5 (TeNbTm, and Tm3+:TeO2-K2O-Nb2O5 (TeNbKTm, primarily for 2-μm laser applications. Tellurite glasses were prepared at different doping concentrations in order to investigate the effect of Tm3+ ion concentration as well as host composition on the stimulated emission cross sections and the luminescence quantum efficiencies. By performing Judd–Ofelt analysis, we determined the average radiative lifetimes of the 3H4 level to be 2.55 ± 0.07 ms, 2.76 ± 0.03 ms and 2.57 ± 0.20 ms for the TeZnTm, TeNbTm and TeNbKTm samples, respectively. We clearly observed the effect of the cross-relaxation, which becomes significant at higher Tm2O3 concentrations, leading to the quenching of 1460-nm emission and enhancement of 1860-nm emission. Furthermore, with increasing Tm2O3 concentrations, we observed a decrease in the fluorescence lifetimes as a result of the onset of non-radiative decay. For the 3H4 level, the highest obtained quantum efficiency was 32% for the samples with the lowest Tm2O3 ion concentration. For the 1860-nm emission band, the average emission cross section was determined to measure around 6.33 ± 0.34 × 10−21 cm2, revealing the potential of thulium-doped tellurite gain media for 2-μm laser applications in bulk and fiber configurations.

  3. Does the apodized diffractive intraocular lens Acrysof ReSTOR NaturalTM interfere with FDT Matrix perimetry results? A lente difrativa apodizada Acrysof ReSTOR NaturalTM pode interferir nos resultados da perimetria por FDT Matrix?

    Directory of Open Access Journals (Sweden)

    Karine Duarte Bojikian

    2009-12-01

    Full Text Available PURPOSE: To compare the effect of an apodized diffractive intraocular lens (IOL (Acrysof ReSTOR NaturalTM and its yellow counterpart (Natural IQ TM on frequency doubling technology (FDT perimetry results. METHODS: This study included 37 eyes from 22 patients at the "Centro Oftalmológico Tranjan" who had undergone uncomplicated phacoemulsification and intraocular lens implantation (17 Acrysof ReSTOR NaturalTM, 20 Natural IQ TM performed by the same surgeon, at least three months prior to the study. Patients were subject to frequency doubling technology Matrix Perimeter testing. RESULTS: The patients were between 41 to 79 years old (mean, 70.78 ± 9.83 in the Natural IQ TM and 49 to 81 years old (mean, 67.11± 11.48 in the Acrysof ReSTOR NaturalTM group, and the mean IOP was 13.64 ± 2.02 mmHg in the Natural IQ TM 12.94 ± 1.39 mmHg in the Acrysof ReSTOR NaturalTM group. The mean pupillary diameter under scotopic conditions was 6.63 ± 1.16 mm in the Natural IQ TM group and 7.20 ± 1.8 mm in the Acrysof ReSTOR NaturalTM group (p=0.20. The mean deviation was -1.83 ± 3.46 dB in the Natural IQ TM group and -1.77 ± 3.94 dB in the Acrysof ReSTOR NaturalTM group (p=0.28. The pattern standard deviation was 3.49 ± 0.79 dB in the Natural IQ TM group and 3.20 ± 0.86 dB in the Acrysof ReSTOR NaturalTM group (p=0.27. CONCLUSION: There was no difference in the results of FDT Matrix perimetry in eyes that received apodized diffractive IOLs implant or eyes that received monofocal intraocular lens implant.OBJETIVO: Comparar o efeito da lente difrativa apodizada (Acrysof ReSTOR NaturalTM e da lente de mesma plataforma amarela (Natural IQ TM sobre os resultados da perimetria de dupla frequência (FDT. MÉTODOS: O estudo incluiu 37 olhos de 22 pacientes do Centro Oftalmológico Tranjan que foram submetidos a cirurgia de facoemulsificação e implante de lentes intraoculares (17 Acrysof ReSTOR NaturalTM, 20 Natural IQ TM sem complicações, realizadas pelo mesmo

  4. Analysis of CMOS Compatible Cu-Based TM-Pass Optical Polarizer

    KAUST Repository

    Ng, Tien Khee

    2012-02-10

    A transverse-magnetic-pass (TM-pass) optical polarizer based on Cu complementary metal-oxide-semiconductor technology platform is proposed and analyzed using the 2-D method-of-lines numerical model. In designing the optimum configuration for the polarizer, it was found that the metal-insulator-metal (MIM) polarizer structure is superior compared to the insulator-metal-insulator polarizer structure due to its higher polarization extinction ratio (PER) and low insertion loss. An optimized MIM TM-pass polarizer exhibits simulated long wavelength pass filter characteristics of > ?1.2 ?m, with fundamental TM 0 and TE 0 mode transmissivity of >70% and <5%, respectively, and with PER ?11.5 dB in the wavelength range of 1.2-1.6 ?m. The subwavelength and submicrometer features of this TM-polarizer are potentially suitable for compact and low power photonics integrated circuit implementation on silicon-based substrates. © 1989-2012 IEEE.

  5. Comparison of the TL intensity of the sintered composites of CaSO4+Tm

    International Nuclear Information System (INIS)

    Junot, O.D.; Sousa, F.L. de; Chagas, M.A.P.; Souza, D.N.

    2009-01-01

    The objective of this work is to compare the thermoluminescent intensity (TL) of CaSO 4 +Tm, CaSO 4 +Tm+glass and glass+Tm composites for use as thermoluminescent dosimeter (TLD). The route used to prepare the CaSO 4 +Tm and the CaSO 4 +Tm+glass was by mixing 1 g of CaSO 4 with 0.02 g of thulium oxide (99,9% purity) and 0.3 g of commercial and colorless glass. To mixing the composites were taken to a magnetic stirrer for 30 min with 10 mL of distilled water for better homogenization. The powder mixtures were dried in a stove at 100 deg C for 24 h. After drying, it was added polyvinyl alcohol (PVA) to improve the binding material. The pellets were compacted by application of an uniaxial pressing and sintered at 700 deg C/ 6 h. The route used in the preparation of glass+Tm pellets was similar to one previously mentioned, except by the use of 1 g of glass and 0.02 of Tm. After the sintering, the pellets dimensions were 1 mm thick and 6 mm in diameter. All samples were irradiated by a beta source ( 90 Sr + 90 Y) and received doses from 1.00 Gy to 20 Gy. Each composite presented a characteristic emission curve. The dosimeter of CaSO 4 +Tm+glass presented two peaks, the first at 115 deg C, and the second, very intense, ate 150 deg C. The CaSO 4 +Tm dosimeter showed a less intense peak at 140 deg C and another, more intense, at 235 deg C. In the composites of glass+Tm, the most intense peak has a thermoluminescent signal 94,04% lower than the most intense peak of CaSO 4 +Tm+glass and 81.57% lower than the most intense peak of CaSO 4 +Tm. After the analysis of TL emission curves, we observed that the CaSO 4 +Tm+glass have the highest TL intensity and a TL response proportional to the dose absorbed. (author)

  6. Cytoskeletal Tropomyosin Tm5NM1 Is Required for Normal Excitation–Contraction Coupling in Skeletal Muscle

    OpenAIRE

    Vlahovich, Nicole; Kee, Anthony J.; Van der Poel, Chris; Kettle, Emma; Hernandez-Deviez, Delia; Lucas, Christine; Lynch, Gordon S.; Parton, Robert G.; Gunning, Peter W.; Hardeman, Edna C.

    2009-01-01

    The functional diversity of the actin microfilaments relies in part on the actin binding protein tropomyosin (Tm). The muscle-specific Tms regulate actin-myosin interactions and hence contraction. However, there is less known about the roles of the numerous cytoskeletal isoforms. We have shown previously that a cytoskeletal Tm, Tm5NM1, defines a Z-line adjacent cytoskeleton in skeletal muscle. Recently, we identified a second cytoskeletal Tm in this region, Tm4. Here we show that Tm4 and Tm5N...

  7. Energy transfer upconversion in Er3+-Tm3+ codoped sodium silicate glass

    Science.gov (United States)

    Kumar, Vinod; Pandey, Anurag; Ntwaeaborwa, O. M.; Swart, H. C.

    2018-04-01

    Er3+/Tm3+ doped and codoped Na2O-SiO2-ZnO (NSZO) glasses were prepared by the conventional melt-quenching method. The amorphous nature of the prepared glasses was confirmed by the X-ray diffraction analysis. The optical absorption spectrum displayed several peaks, which correspond to Er3+ and Tm3+ dopant ions embedded into the NSZO glass. Both dopants experienced upconversion emission under 980 nm excitation. Efficient energy transfer from Er3+ to Tm3+ was observed in the co-doped samples to enhance the near infrared emission of the Tm3+ ions.

  8. Cytoskeletal Tropomyosin Tm5NM1 Is Required for Normal Excitation–Contraction Coupling in Skeletal Muscle

    Science.gov (United States)

    Vlahovich, Nicole; Kee, Anthony J.; Van der Poel, Chris; Kettle, Emma; Hernandez-Deviez, Delia; Lucas, Christine; Lynch, Gordon S.; Parton, Robert G.; Gunning, Peter W.

    2009-01-01

    The functional diversity of the actin microfilaments relies in part on the actin binding protein tropomyosin (Tm). The muscle-specific Tms regulate actin-myosin interactions and hence contraction. However, there is less known about the roles of the numerous cytoskeletal isoforms. We have shown previously that a cytoskeletal Tm, Tm5NM1, defines a Z-line adjacent cytoskeleton in skeletal muscle. Recently, we identified a second cytoskeletal Tm in this region, Tm4. Here we show that Tm4 and Tm5NM1 define separate actin filaments; the former associated with the terminal sarcoplasmic reticulum (SR) and other tubulovesicular structures. In skeletal muscles of Tm5NM1 knockout (KO) mice, Tm4 localization was unchanged, demonstrating the specificity of the membrane association. Tm5NM1 KO muscles exhibit potentiation of T-system depolarization and decreased force rundown with repeated T-tubule depolarizations consistent with altered T-tubule function. These results indicate that a Tm5NM1-defined actin cytoskeleton is required for the normal excitation–contraction coupling in skeletal muscle. PMID:19005216

  9. Cytoskeletal tropomyosin Tm5NM1 is required for normal excitation-contraction coupling in skeletal muscle.

    Science.gov (United States)

    Vlahovich, Nicole; Kee, Anthony J; Van der Poel, Chris; Kettle, Emma; Hernandez-Deviez, Delia; Lucas, Christine; Lynch, Gordon S; Parton, Robert G; Gunning, Peter W; Hardeman, Edna C

    2009-01-01

    The functional diversity of the actin microfilaments relies in part on the actin binding protein tropomyosin (Tm). The muscle-specific Tms regulate actin-myosin interactions and hence contraction. However, there is less known about the roles of the numerous cytoskeletal isoforms. We have shown previously that a cytoskeletal Tm, Tm5NM1, defines a Z-line adjacent cytoskeleton in skeletal muscle. Recently, we identified a second cytoskeletal Tm in this region, Tm4. Here we show that Tm4 and Tm5NM1 define separate actin filaments; the former associated with the terminal sarcoplasmic reticulum (SR) and other tubulovesicular structures. In skeletal muscles of Tm5NM1 knockout (KO) mice, Tm4 localization was unchanged, demonstrating the specificity of the membrane association. Tm5NM1 KO muscles exhibit potentiation of T-system depolarization and decreased force rundown with repeated T-tubule depolarizations consistent with altered T-tubule function. These results indicate that a Tm5NM1-defined actin cytoskeleton is required for the normal excitation-contraction coupling in skeletal muscle.

  10. Walk Score(TM), Perceived Neighborhood Walkability, and walking in the US.

    Science.gov (United States)

    Tuckel, Peter; Milczarski, William

    2015-03-01

    To investigate both the Walk Score(TM) and a self-reported measure of neighborhood walkability ("Perceived Neighborhood Walkability") as estimators of transport and recreational walking among Americans. The study is based upon a survey of a nationally-representative sample of 1224 American adults. The survey gauged walking for both transport and recreation and included a self-reported measure of neighborhood walkability and each respondent's Walk Score(TM). Binary logistic and linear regression analyses were performed on the data. The Walk Score(TM) is associated with walking for transport, but not recreational walking nor total walking. Perceived Neighborhood Walkability is associated with transport, recreational and total walking. Perceived Neighborhood Walkability captures the experiential nature of walking more than the Walk Score(TM).

  11. The role of upstream sequences in selecting the reading frame on tmRNA

    Directory of Open Access Journals (Sweden)

    Dewey Jonathan D

    2008-06-01

    Full Text Available Abstract Background tmRNA acts first as a tRNA and then as an mRNA to rescue stalled ribosomes in eubacteria. Two unanswered questions about tmRNA function remain: how does tmRNA, lacking an anticodon, bypass the decoding machinery and enter the ribosome? Secondly, how does the ribosome choose the proper codon to resume translation on tmRNA? According to the -1 triplet hypothesis, the answer to both questions lies in the unique properties of the three nucleotides upstream of the first tmRNA codon. These nucleotides assume an A-form conformation that mimics the codon-anticodon interaction, leading to recognition by the decoding center and choice of the reading frame. The -1 triplet hypothesis is important because it is the most credible model in which direct binding and recognition by the ribosome sets the reading frame on tmRNA. Results Conformational analysis predicts that 18 triplets cannot form the correct structure to function as the -1 triplet of tmRNA. We tested the tmRNA activity of all possible -1 triplet mutants using a genetic assay in Escherichia coli. While many mutants displayed reduced activity, our findings do not match the predictions of this model. Additional mutagenesis identified sequences further upstream that are required for tmRNA function. An immunoblot assay for translation of the tmRNA tag revealed that certain mutations in U85, A86, and the -1 triplet sequence result in improper selection of the first codon and translation in the wrong frame (-1 or +1 in vivo. Conclusion Our findings disprove the -1 triplet hypothesis. The -1 triplet is not required for accommodation of tmRNA into the ribosome, although it plays a minor role in frame selection. Our results strongly disfavor direct ribosomal recognition of the upstream sequence, instead supporting a model in which the binding of a separate ligand to A86 is primarily responsible for frame selection.

  12. Construction of covalently coupled, concatameric dimers of 7TM receptors

    DEFF Research Database (Denmark)

    Terpager, Marie; Scholl, D Jason; Kubale, Valentina

    2009-01-01

    -Ala repeats flanked by flexible spacers and positively charged residues to ensure correct inside-out orientation plus an extracellular HA-tag to construct covalently coupled dimers of 7TM receptors. Such 15 TM concatameric homo- and heterodimers of the beta(2)-adrenergic and the NK(1) receptors, which...... for either of the protomers, which was not observed upon simple coexpression of the two receptors. It is concluded that covalently joined 7TM receptor dimers with surprisingly normal receptor properties can be constructed with use of an artificial transmembrane connector, which perhaps can be used to fuse...

  13. Integrated Cu-based TM-pass polarizer using CMOS technology platform

    KAUST Repository

    Ng, Tien Khee

    2010-01-01

    A transverse-magnetic-pass (TM-pass) copper (Cu) polarizer is proposed and analyzed using the previously published two-dimensional Method-of-Lines beam-propagation model. The proposed polarizer exhibits a simulated high-pass filter characteristics, with TM0 and TE0 mode transmissivity of >70% and <5%, respectively, in the wavelength regime of 1.2-1.6 μm. The polarization extinction ratio (PER) given by 10 log10 (PTM0)/(PTE0) is +11.5 dB across the high-pass wavelength regime. To the best of the authors\\' knowledge, we report here the smallest footprint CMOS-platform compatible TM-polarizer.

  14. Powernext Day-AheadTM products and market organization

    International Nuclear Information System (INIS)

    2004-06-01

    The introduction of a power exchange in France is a direct response to the opening up of the European electricity markets. Powernext SA is a Multilateral Trading Facility in charge of managing the French power exchange through an optional and anonymous organised exchange offering: - Day-ahead contracts for the management of volume risk on Powernext Day-Ahead TM since 21 November 2001, - Medium term contracts for the management of price risk on Powernext Futures TM since 18 June 2004. This document presents the principle of the trading of hourly contracts on Powernext Day-Ahead TM , the accessibility of the market, the SAPRI trading platform operated by Nord Pool, the Scandinavian power exchange, the validation of the auction results, the collaboration with LCH.Clearnet SA to secure and facilitate the transactions, and the delivery guarantee implemented by RTE (the French energy transport network). (J.S.)

  15. Thermo-selective Tm(x)Ti(1-x)O(2-x/2) nanoparticles: from Tm-doped anatase TiO2 to a rutile/pyrochlore Tm2Ti2O7 mixture. An experimental and theoretical study with a photocatalytic application.

    Science.gov (United States)

    Navas, Javier; Sánchez-Coronilla, Antonio; Aguilar, Teresa; De los Santos, Desireé M; Hernández, Norge C; Alcántara, Rodrigo; Fernández-Lorenzo, Concha; Martín-Calleja, Joaquín

    2014-11-07

    This is an experimental and theoretical study of thulium doped TiO2 nanoparticles. From an experimental perspective, a method was used to synthesize thulium-doped TiO2 nanoparticles in which Tm(3+) replaces Ti(4+) in the lattice, which to our knowledge has neither been reported nor studied theoretically so far. Different proportions of anatase and rutile phases were obtained at different annealing temperatures, and XRD and Raman spectroscopy also revealed the presence of a pyrochlore phase (Tm2Ti2O7) at 1173 K. Thus, the structure of the Tm-doped nanoparticles was thermally-controlled. Furthermore, XPS showed the presence of Tm(3+) in the samples synthesized, which produces oxygen vacancies to maintain the local neutrality in the lattice. The presence of Tm(3+) in the samples led to changes in the UV-Vis absorption spectra, so they showed photoluminescence properties and new states in the band gap, which produce a new lower energy electronic transition than the main TiO2 one. Periodic DFT calculations were performed to understand the experimentally produced structures. The production of oxygen vacancies was analysed and the changes generated in the structure were fully detailed. The DOS and PDOS analyses confirmed the experimental results obtained using UV-Vis spectroscopy, and showed that the new electronic states in the band gap are due to interactions of the f state of Tm and the p state of O. Likewise, the charge study and the ELF analysis indicate that when Tm is introduced into the TiO2 structure, the Ti-O bond around the oxygen vacancy is strengthened. Finally, an example of a photocatalytic application was developed to show the high efficiency of the samples due to the heterojunction in the interfaces of the phases in the samples, which improved the charge separation and the good charge carrier mobility due to the presence of the pyrochlore phase, as was also shown theoretically.

  16. ALDUO(TM) Algae Cultivation Technology for Delivering Sustainable Omega-3s, Feed, and Fuel

    Energy Technology Data Exchange (ETDEWEB)

    Bai, Xuemei [Cellana LLC

    2012-09-24

    * ALDUO(TM) Algae Production Technology Cellana?s Proprietary, Photosynthetic, & Proven * ALDUO(TM) Enables Economic Algae Production Unencumbered by Contamination by Balancing Higher-Cost PBRs with Lower-Cost Open Ponds * ALDUO(TM) Advantages * ALDUO(TM) Today o Large collection of strains for high value co-products o Powerful Mid-scale Screening & Optimization System o Solution to a Conflicting Interest o Split Pond Yield Enhancement o Heterotrophy & mixotrophy as a "finishing step" o CO2 Mitigation-flue Gas Operation o Worldwide Feed Trials with Livestock & Aquatic Species * ALDUO(TM) Technology Summarized

  17. Structural, Electronic and Elastic Properties of Heavy Fermion YbTM2 (TM= Ir and Pt) Laves Phase Compounds

    Science.gov (United States)

    Pawar, H.; Shugani, M.; Aynyas, M.; Sanyal, S. P.

    2018-02-01

    The structural, electronic and elastic properties of YbTM2 (TM = Ir and Pt) Laves phase intermetallic compounds which crystallize in cubic (MgCu2-type) structure, have been investigated using ab-initio full potential linearized augmented plane wave (FP-LAPW) method with LDA and LDA+U approximation. The calculated ground state properties such as lattice parameter (a0), bulk modulus (B) and its pressure derivative (B‧) are in good agreement with available experimental and theoretical data. The electronic properties are analyzed from band structures and density of states. Elastic constants are predicted first time for these compounds which obey the stability criteria for cubic system.

  18. Intense blue upconversion emission and intrinsic optical bistability in Tm3+/Yb3+/Zn2+ tridoped YVO4 phosphors

    Science.gov (United States)

    Yadav, Manglesh; Mondal, Manisha; Mukhopadhyay, Lakshmi; Rai, Vineet Kumar

    2018-04-01

    Tm3+/Yb3+/Zn2+:yttrium metavanadate (YVO4) phosphors prepared through chemical coprecipitation and the solid state reaction method have been structurally characterized by an x-ray diffraction (XRD) study. Photoluminescence study of the developed phosphors under ultraviolet (UV) and near infrared (NIR) excitation has been performed. The excitation spectrum of the tetragonal zircon type YVO4 phosphors corresponding to the emission at ˜476 nm exhibits a broad excitation peak in the 250-350 nm region, which is due to charge distribution in the {{{{VO}}}4}3- group. Under 980 nm CW diode laser excitation, enhancements of about ˜3000 times and ˜40 times have been observed for the blue band in the tridoped Tm3+Yb3+Zn2+:YVO4 phosphors compared to those of the Tm3+:YVO4 singly and Tm3+/Yb3+:YVO4 codoped phosphors, respectively. A downconversion (DC) emission study shows an enhancement of about ˜50 times for the blue band in the tridoped phosphors compared to that of the singly doped phosphors. Optical bistability (OB) behavior of the developed phosphors has been also investigated upon 980 nm excitation. The calculated Commission Internationale de l’Éclairage (CIE) color coordinates lie in the blue region with 96.5% color purity under 980 nm excitation, having a color temperature of ˜3400 K. Our observations show that the developed phosphors may be suitably used in dual mode luminescence spectroscopy, display devices, and UV LED chips.

  19. Efficient CW diode-pumped Tm, Ho:YLF laser with tunability near 2.067 microns

    Science.gov (United States)

    Mcguckin, B. T.; Menzies, Robert T.

    1992-01-01

    A conversion efficiency of 42 percent and slope efficiency of approximately 60 percent relative to absorbed pump power are reported from a continuous wave diode-pumped Tm, Ho:YLF laser at 2 microns with output power of 84 mW at sub-ambient temperatures. The emission spectrum is etalon tunable over a range of 16/cm centered on 2.067 microns, with fine tuning capability of the transition frequency with crystal temperature at a measured rate of about -0.03/cm-K. The effective emission cross section is measured to be 5 x 10 exp -21 sq cm. These and other aspects of the laser performance are discussed in the context of calculated atmospheric absorption characteristics in this spectral region and potential use in remote sensing applications.

  20. Veritex(TM) Patches for Structural Repair and Re-Use, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — Cornerstone Research Group, Inc. (CRG) proposes to develop a bonded composite patch repair and re-use system based on CRG's VeritexTM materials. VeritexTM is a...

  1. 2-micron lasing in Tm:Lu2O3 ceramic: initial operation

    Science.gov (United States)

    Vetrovec, John; Filgas, David M.; Smith, Carey A.; Copeland, Drew A.; Litt, Amardeep S.; Briscoe, Eldridge; Schirmer, Ernestina

    2018-03-01

    We report on initial lasing of Tm:Lu2O3 ceramic laser with tunable output in the vicinity of 2 μm. Tm:Lu2O3 ceramic gain materials offer a much lower saturation fluence than the traditionally used Tm:YLF and Tm:YAG materials. The gain element is pumped by 796 nm diodes via a "2-for-1" crossrelaxation energy transfer mechanism, which enables high efficiency. The high thermal conductivity of the Lu2O3 host ( 18% higher than YAG) in combination with low quantum defect of 20% supports operation at high-average power. Konoshima's ceramic fabrication process overcomes the scalability limits of single crystal sesquioxides. Tm:Lu2O3 offers wide-bandwidth amplification of ultrashort pulses in a chirped-pulse amplification (CPA) system. A laser oscillator was continuously tuned over a 230 nm range from 1890 to 2120 nm while delivering up to 43W QCW output with up to 37% efficiency. This device is intended for initial testing and later seeding of a multi-pass edge-pumped disk amplifier now being developed by Aqwest which uses composite Tm:Lu2O3 disk gain elements.

  2. Growth and optical characteristics of Tm-doped AlGaN layer grown by organometallic vapor phase epitaxy

    Science.gov (United States)

    Takatsu, J.; Fuji, R.; Tatebayashi, J.; Timmerman, D.; Lesage, A.; Gregorkiewicz, T.; Fujiwara, Y.

    2018-04-01

    We report on the growth and optical properties of Tm-doped AlGaN layers by organometallic vapor phase epitaxy (OMVPE). The morphological and optical properties of Tm-doped GaN (GaN:Tm) and Tm-doped AlGaN (AlGaN:Tm) were investigated by Nomarski differential interference contrast microscopy and photoluminescence (PL) characterization. Nomarski images reveal an increase of surface roughness upon doping Tm into both GaN and AlGaN layers. The PL characterization of GaN:Tm shows emission in the near-infrared range originating from intra-4f shell transitions of Tm3+ ions. In contrast, AlGaN:Tm also exhibits blue light emission from Tm3+ ions. In that case, the wider band gap of the AlGaN host allows energy transfer to higher states of the Tm3+ ions. With time-resolved PL measurements, we could distinguish three types of luminescent sites of Tm3+ in the AlGaN:Tm layer, having different decay times. Our results confirm that Tm ions can be doped into GaN and AlGaN by OMVPE, and show potential for the fabrication of novel high-color-purity blue light emitting diodes.

  3. Evaluation of Cross-Section Data from Threshold to 40 MeV for some Neutron Reactions Important for Fusion Dosimetry Applications. Part 2 Evaluation of the Excitation Functions for the 59Co(n,3n)57Co, 89Y(n,2n)88Y, 93Nb(n,2n)92mNb, 169Tm(n,2n)168Tm and 209Bi(n,3n)207Bi Reactions

    International Nuclear Information System (INIS)

    Zolotarev, K.I.

    2010-11-01

    Evaluations of cross sections and their associated covariance matrices have been carried out for five dosimetry reactions: excitation functions were re-evaluated for the 89 Y(n,2n) 88 Y, 93 Nb(n,2n) 92 mNb and 169 Tm(n,2n) 168 Tm reactions over the neutron energy range from threshold up to 40 MeV; excitation functions were re-evaluated for the 59 Co(n,3n) 57 Co and 209 Bi(n,3n) 207 Bi reactions over the neutron energy range from threshold to 85 and 45 MeV, respectively. Uncertainties in the cross sections for all of those reactions were also derived in the form of relative covariance matrices. Benchmark calculations performed for 235 U thermal fission and 252 Cf spontaneous fission neutron spectra show that the integral cross sections calculated from the newly evaluated excitation functions exhibit improved agreement with related experimental data when compared with the equivalent data from the IRDF-2002 library. (author)

  4. Study of yrast band in {sup 155}Tm

    Energy Technology Data Exchange (ETDEWEB)

    Raut, R. [Nuclear and Atomic Physics Division, Saha Institute of Nuclear Physics, 1/AF Bidhannagar, Kolkata-700064 (India); Bhowal, S. [Department of Physics, Surendranath College (Evening), M.G. road, Kolkata-700009 (India); Ganguly, S.; Kshetri, R.; Banerjee, P.; Bhattacharya, S. [Nuclear and Atomic Physics Division, Saha Institute of Nuclear Physics, 1/AF Bidhannagar, Kolkata-700064 (India); Bhowmik, R.K. [Inter University Accelerator Center, Aruna Asaf Ali Marg, New Delhi (India); Dasmahapatra, B. [Nuclear and Atomic Physics Division, Saha Institute of Nuclear Physics, 1/AF Bidhannagar, Kolkata-700064 (India); Gangopadhyay, G. [Department of Physics, University College of Science Technology, 92, A.P.C. road, Kolkata-700073 (India); Mukherjee, A. [Nuclear and Atomic Physics Division, Saha Institute of Nuclear Physics, 1/AF Bidhannagar, Kolkata-700064 (India); Muralithar, S. [Inter University Accelerator Center, Aruna Asaf Ali Marg, New Delhi (India); SahaSarkar, M. [Nuclear and Atomic Physics Division, Saha Institute of Nuclear Physics, 1/AF Bidhannagar, Kolkata-700064 (India); Singh, R.P. [Inter University Accelerator Center, Aruna Asaf Ali Marg, New Delhi (India); Goswami, A. [Nuclear and Atomic Physics Division, Saha Institute of Nuclear Physics, 1/AF Bidhannagar, Kolkata-700064 (India)], E-mail: asimananda.goswami@saha.ac.in

    2007-10-01

    The nucleus {sup 155}Tm has been studied by a detailed in-beam gamma spectroscopy following the reaction {sup 144}Sm({sup 14}N, 3n){sup 155}Tm, at a beam energy, E{sub lab}=70MeV, using a Compton suppressed gamma detector array. More than 25 new gamma transitions have been placed in the proposed scheme and the latter has been extended upto a spin-parity of (51/2{sup -}) at an excitation energy {approx} 6 MeV.

  5. The KiteShip (TM) project

    Energy Technology Data Exchange (ETDEWEB)

    De winter, Francis; Swenson, Ronald B; Culp, David [Santa Cruz, CA (United States)

    2000-07-01

    Foreseeable crude oil shortages provide an incentive to use wind power in the merchant marine again, to save fuel by providing propulsion power. Out prototype KiteShip (TM), a lightweight fiberglass proa 7 m long, has been sailed with 2 different sizes of kites in fresh water. The kites are shaped like parafoil wings, with areas of 4 sq m and 9 sq m. Steering is accomplished with two coupled rudders, one fore and one aft. We have been encouraged by the boat speed and the handling, although we have encountered only light winds up to now, of no more than about 20 km/ht. In the next phase we will employ a custom-built kite of 2 sq m. and will also start sailing in the ocean with heavier winds, of 40 km/hr and above. [Spanish] La escasez previsible de petroleo motiva volver a utilizar la fuerza del viento en la marina mercante, para ahorrar combustible al suministrar la potencia de propulsion. Nuestro prototipo KiteShip (MR), con una proa ligera de fibra de vidrio con 7 m de longitud, ha navegado con dos diferentes tipos de vela ({sup k}ite{sup )} en agua dulce. Los kites tienen forma de alas de parafol, con areas de 4 m{sup 2} y 9 m{sup 2}. La direccion se logra con dos timones acoplados, uno en la proa y otro en la popa. Nos entusiasmo la velocidad del bote y su manejo, aunque hemos encontrado hasta ahora solo vientos ligeros de no mas de alrededor de 20 km/hr. En la siguiente fase emplearemos un kite hecho a la medida, de 28 m{sup 2} y tambien comenzaremos a navegar en el oceano con vientos mas fuertes de 40 km/hr o mas.

  6. Powernext futuresTM statistics 31st, July 2004

    International Nuclear Information System (INIS)

    2004-07-01

    The introduction of a power exchange in France is a direct response to the opening up of the European electricity markets. Powernext SA is a Multilateral Trading Facility in charge of managing an optional and anonymous organised exchange offering: - Day-ahead contracts for the management of volume risk on Powernext Day-Ahead TM since 21 November 2001, - Medium term contracts for the management of price risk on Powernext Futures TM since 18 June 2004. This document presents in a series of tables and graphics the July 31, 2004 update of Powernext Futures TM statistics: year, quarter and month contracts for July 2004, base-load and peak-load contracts overview from June 2004 to July 2004 (daily volume in lots, open interest by delivery year in MWh, daily settlement price of the upcoming delivery period, base-load and peak-load price spreads), and market liquidity from mid-June to end of July 2004 (average bid ask spread and availability). (J.S.)

  7. Electromagnetic cloaking devices for TE and TM polarizations

    International Nuclear Information System (INIS)

    Bilotti, Filiberto; Tricarico, Simone; Vegni, Lucio

    2008-01-01

    In this paper, we present the design of an electromagnetic cloaking device working for both transverse electric (TE) and transverse magnetic (TM) polarizations. The theoretical approach to cloaking used here is inspired by the one presented by Alu and Engheta (2005 Phys. Rev. E 72 016623) for TM polarization. The case of TE polarization is firstly considered and, then, an actual inclusion-based cloak for TE polarization is also designed. In such a case, the cloak is made of a mu-near-zero (MNZ) metamaterial, as the dual counterpart of the epsilon-near-zero (ENZ) material that can be used for purely dielectric objects. The operation and the robustness of the cloaking device for the TE polarization is deeply investigated through a complete set of full-wave numerical simulations. Finally, the design and an application of a cloak operating for both TE and TM polarizations employing both magnetic inclusions and the parallel plate medium already used by Silveirinha et al (Phys. Rev. E 75 036603) are presented.

  8. 40 CFR 142.42 - Consideration of a variance request.

    Science.gov (United States)

    2010-07-01

    .... 142.42 Section 142.42 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER... public water system install the best technology, treatment techniques, or other means, which the... including water quality data and pertinent sources of pollution. (2) Source protection measures employed by...

  9. Influence of Tm-doping on microstructure and luminescence behavior of barium strontium titanate thick films

    International Nuclear Information System (INIS)

    Wang Jingyang; Zhang Tianjin; Pan Ruikun; Ma Zhijun; Wang Jinzhao

    2012-01-01

    Tm-doped Ba 0.8 Sr 0.2 TiO 3 thick films were prepared by the screen-printing technique on the alumina substrate. The microstructure of the Tm-doped BST thick films was characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM) and Raman spectroscopy, respectively. All the samples showed a typical perovskite polycrystalline structure when sintered at 1260 °C. The substitution behavior of Tm 3+ ion in BST was found to change with increasing the Tm 3+ concentration. The observed Tm-related red emission reaches the maximum at 0.2 mol% Tm 3+ concentration. The effects of concentration quenching on the luminescence intensity were discussed.

  10. Spectroscopy and microchip laser operation of Tm, Ho:KYW crystals with different Ho concentrations

    Science.gov (United States)

    Gusakova, N. V.; Kurilchik, S. V.; Yasukevich, A. S.; Kisel, V. E.; Dashkevich, V. I.; Orlovich, V. A.; Pavlyuk, A. A.; Vatnik, S. M.; Bagaev, S. N.; Kuleshov, N. V.

    2018-02-01

    The spectroscopic properties of Tm, Ho:KYW crystals with different Ho concentrations were investigated. The diode-pumped microchip laser operation of Tm (5 at.%), Ho (0.5 at.%):KYW and Tm (5 at.%), Ho (1 at.%):KYW was demonstrated. The highest, to our knowledge, output power of 480 mW with slope efficiency of 31% for CW Tm (5 at.%), Ho (0.5 at.%):KYW microchip laser was obtained.

  11. DC Stark addressing for quantum memory in Tm:YAG

    Science.gov (United States)

    Gerasimov, Konstantin; Minnegaliev, Mansur; Urmancheev, Ravil; Moiseev, Sergey

    2017-10-01

    We observed a linear DC Stark effect for 3H6 - 3H4 optical transition of Tm3+ ions in Y3Al5O12. We observed that application of electric field pulse suppresses the two-pulse photon echo signal. If we then apply a second electric pulse of opposite polarity the echo signal is restored again, which indicates the linear nature of the observed effect. The effect is present despite the D2 symmetry of the Tm3+ sites that prohibits a linear Stark effect. Experimental data analysis shows that the observed electric field influence can be attributed to defects that break the local crystal field symmetry near Tm3+ ions. Using this effect we demonstrate selective retrieval of light pulses in two-pulse photon echo.

  12. Counting Tm dopant atoms around GaN dots using high-angle annular dark field images

    International Nuclear Information System (INIS)

    Rouvière, J-L; Okuno, H; Jouneau, P H; Bayle-Guillemaud, P; Daudin, B

    2011-01-01

    High resolution Z-contrast STEM imaging is used to study the Tm doping of GaN quantum dots grown in AlN by molecular beam epitaxy (MBE). High-angle annular dark field (HAADF) imaging allows us to visualize directly individual Tm atoms in the AlN matrix and even to count the number of Tm atoms in a given AlN atomic column. A new visibility coefficient to determine quantitatively the number of Tm atoms in a given atomic column is introduced. It is based on locally integrated intensities rather than on peak intensities of HAADF images. STEM image simulations shows that this new visibility is less sensitive to the defocus-induced blurring or to the position of the Tm atom within the thin lamella. Most of the Tm atoms diffuse out of GaN dots. Tm atoms are found at different positions in the AlN matrix, (i) Above the wetting layer, Tm atoms are spread within a thickness of 14 AlN monolayers (MLs). (ii) Above the quantum dots all the Tm are located in the same plane situated at 2-3 MLs above the apex of the GaN dot, i.e. at a distance of 14 MLs from the wetting layer, (iii) In addition, Tm can diffuse very far from the GaN dot by following threading dislocations lines.

  13. Comparison of ATTILA{sup TM} and MCNP{sup TM} for fusion applications

    Energy Technology Data Exchange (ETDEWEB)

    Loughlin, M. [UKAEA Fusion, Culham Science Centre, Abingdon, Oxfordshire, OX (United Kingdom); Wareing, T.; Barnett, A.; Failla, G.; McGhee, J. [Transpire Inc., Gig Harbor WA (United States)

    2005-07-01

    This paper describes comparison of the results of neutron transport calculations using two very different codes. ATTILA{sup TM} is a discrete ordinates radiation transport code which models complex 3-D geometries using arbitrary tetrahedra. MCNP{sup TM} is a Monte-Carlo radiation transport code which models the geometry using a combinatorial representation. This code is more widely known within the fusion community where it has been extensively used. In contrast, this is the first reporting of the use of ATTILA for fusion applications. The purpose of the work described herein was to compare calculations by each code of the neutron spectra at points around a greatly simplified representation of a typical fusion experiment. Spectra, in twenty-seven energy groups, were calculated at five locations which are typical of fusion neutronics problems; these are i) within the torus wall, ii) opposite a port, iii) near the torus hall floor, iv) at a straight penetration through the torus hall roof, and v) at the exit of a labyrinth through the wall. A solution was obtained from ATTILA in one 24 hour run on a single processor. An MCNP run of a similar duration was required on 18 parallel processors. Excellent agreement was obtained at all locations with only some minor disparities at thermal neutron energies. (authors)

  14. Spectroscopic analysis of LiTmF4

    DEFF Research Database (Denmark)

    Christensen, H.P.

    1979-01-01

    The absorption spectra of Tm3+ in LiTmF4 have been measured at 2, 10, 30, and 50 K in the spectral interval 4000-25 000 cm-1. The energy levels of the ground-state configuration were calculated by diagonalizing the Hamiltonian of the electron-electron interaction, the spin-orbit coupling......+, and Er3+ in LiLnF4, and they follow a common trend. The intensities of the transitions from the ground state were calculated in the Judd-Ofelt scheme, fitting six complex intensity parameters A(kqλ) for best agreement with the experimentally observed intensities. The model was only able to give a rough...

  15. The T.M. Calorimeter

    International Nuclear Information System (INIS)

    Mas, P.; Goer, J. de

    1970-01-01

    The T.M. calorimeter is the isothermal type. It consists only of a sample of graphite and a jacket of stainless steel filled with nitrogen. The chromel-alumel thermocouples which measure the temperature difference between the sample and the jacket also serve to suspend the sample. The jacket is kept at a constant temperature: i.e. that of the water in the swimming pool

  16. Efficient 2-μm Tm:YAP Q-switched and CW lasers

    Science.gov (United States)

    Hays, A. D.; Cole, Brian; King, Vernon; Goldberg, Lew

    2018-02-01

    Highly efficient, diode pumped Tm:YAP lasers generating emission in the 1.85-1.94 μm range are demonstrated and characterized. Laser optical efficiencies of 51% and 45%, and electrical efficiencies of 31% and 25% are achieved under CW and Q-switched operation, respectively. Laser performance was characterized for maximum average powers up to 20W with various cavity configurations, all using an intra-cavity lens to compensate for thermal lensing in the Tm:YAP crystal. Q-switched lasers incorportating a Cr:ZnS saturable absorber (SA), resonant mechanical mirror scanner, or acousto-optic modulator were characterized. To enable higher average output powers, measurements of the thermal lens were conducted for the Tm:YAP crystal as a function of pump power and were compared to values predicted by a finiteelement- analysis (FEA) thermal-optical model of the Tm:YAP crystal. A resonator model is developed to incorporate this calculated thermal lens and its effect on laser performance. This paper will address approaches for improving the performance of Tm:YAP lasers, and means for achieving increased average output powers while maintaining high optical efficiency for both SA and mechanical Q-switching.

  17. Health technology assessment demonstrates efficient health promotion bu Transcendental Meditation (TM)

    DEFF Research Database (Denmark)

    Larsen, Torben

    2002-01-01

    -actualisation; (3) Independence of stimulantia including tobacco and alcohol; (4) Cardiologic health. RESULTS: This health promotion is explained by a cybernetic model based on 'The Limbic System'. A sample of records collected by the Internet shows significant compliance between the self-reports of TM......-practitioners and controls without specific health promotion. The TM-group has a relative high level of education. TM is organized as a private, standardised dissemination of the original, Indoeuropean mantrameditation. This standardisation creates economies-of-scale 1) using local instructors with a short education, 2...

  18. High quality TmIG films with perpendicular magnetic anisotropy grown by sputtering

    Science.gov (United States)

    Wu, C. N.; Tseng, C. C.; Yeh, S. L.; Lin, K. Y.; Cheng, C. K.; Fanchiang, Y. T.; Hong, M.; Kwo, J.

    Ferrimagnetic thulium iron garnet (TmIG) films grown on gadolinium gallium garnet substrates recently showed stress-induced perpendicular magnetic anisotropy (PMA), attractive for realization of quantum anomalous Hall effect (QAHE) of topological insulator (TI) films via the proximity effect. Moreover, current induced magnetization switching of Pt/TmIG has been demonstrated for the development of room temperature (RT) spintronic devices. In this work, high quality TmIG films (about 25nm) were grown by sputtering at RT followed by post-annealing. We showed that the film composition is tunable by varying the growth parameters. The XRD results showed excellent crystallinity of stoichiometric TmIG films with an out-of-plane lattice constant of 1.2322nm, a narrow film rocking curve of 0.017 degree, and a film roughness of 0.2 nm. The stoichiometric films exhibited PMA and the saturation magnetization at RT was 109 emu/cm3 (RT bulk value 110 emu/cm3) with a coercive field of 2.7 Oe. In contrast, TmIG films of Fe deficiency showed in-plane magnetic anisotropy. The high quality sputtered TmIG films will be applied to heterostructures with TIs or metals with strong spin-orbit coupling for novel spintronics.

  19. ACR-1000TM Project - Licensing Opportunities and Challenges

    International Nuclear Information System (INIS)

    Popov, N.; Doerffer, S.; Ion, R.; Hopwood, J.

    2011-01-01

    Atomic Energy of Canada Limited (AECL) has developed the Advanced CANDU Reactor TM 1 1000 (ACR-1000 TM ) as an evolutionary advancement of the current CANDU 6 reactor. The ACR-1000 design has evolved from AECL's in-depth knowledge of CANDU TM systems, components, and materials, as well as the experience and feedback received from owners and operators of CANDU plants. The ACR design retains the proven strengths and features of CANDU reactors, while incorporating innovations and state-of-the-art technology. It also features major improvements in economics, inherent safety characteristics, and performance, while retaining the proven benefits of the CANDU family of nuclear power plants. To ensure that the ACR design is compliant with Canadian and international requirements, regulatory pre-project reviews of the ACR-1000 (and ACR-700 TM 1 with lower output) were conducted early in the design work. The regulatory feedback from these pre-project regulatory reviews helped AECL to better understand regulatory expectations in Canada, US and the UK, and to make further advancements and improvements in the ACR design to meet the Canadian and international regulatory requirements. This paper provides an overview of the key design features of the ACR-1000 reactor design, and summary of the pre-project reviews by those above-mentioned regulatory bodies, demonstrating opportunities and challenges in licensing process of and pointing to the importance of efficient vendor-regulator interaction. (author)

  20. Preparation and photoluminescence properties of Tm{sup 3+}-doped ZrO{sub 2} nanotube arrays

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Mingli [School of Materials Science and Engineering, Hebei University of Technology, Tianjin 300130 (China); Zhao, Jianling, E-mail: hebutzhaoj@126.com [School of Materials Science and Engineering, Hebei University of Technology, Tianjin 300130 (China); Xu, Rongqing [Tianjin Zhonghuan Advanced Material & Technology Co., LTD, Tianjin 300384 (China); Fu, Ning [School of Materials Science and Engineering, Hebei University of Technology, Tianjin 300130 (China); Wang, Xixin, E-mail: xixinwang@126.com [School of Materials Science and Engineering, Hebei University of Technology, Tianjin 300130 (China)

    2016-07-25

    Tm{sup 3+}-doped ZrO{sub 2} nanotube arrays were prepared by anodization of a Zr–Tm alloy (3 at.% Tm) obtained by a powder metallurgical method. The morphologies, structures, elemental valence, and photoluminescence properties were characterized by using scanning electron microscope, X-ray diffractometer, X-ray photoelectron spectrometer and photoluminescence analyser, respectively. Results show that preparing conditions and annealing temperatures have significant effects on the crystalline structure and photoluminescence performance. The sample TmZNT-Org prepared in formamide + glycerol organic solution is mainly monoclinic phase and the sample TmZNT-Aq prepared in aqueous solution is mainly tetragonal phase. The sample TmZNT-Org had the strongest photoluminescence peak when annealed at 800 °C, whereas both TmZNT-Aq samples annealed at 600 °C and 800 °C had the strongest photoluminescence peak. The monoclinic phase was conductive to the emission at 454 nm while the tetragonal phase was conductive to the emission at 460 nm. - Highlights: • Tm{sup 3+}-doped ZrO{sub 2} nanotube arrays were prepared by anodization of a Zr-Tm alloy. • Crystal structure had remarkable effects on the photoluminescence properties. • The monoclinic phase was conductive to the emission at 454 nm. • The tetragonal phase was conductive to the emission at 460 nm.

  1. Thermal and optical properties of Tm3+ doped tellurite glasses.

    Science.gov (United States)

    Ozen, G; Demirata, B; Oveçoğlu, M L; Genç, A

    2001-02-01

    Ultraviolet, visible (UV/VIS) and differential thermal analysis (DTA) measurements were carried out in order to investigate the optical and thermal properties of various 0.5 mol.% Tm2O3 containing (1 - x)TeO2 + xLiCl glasses in molar ratio. The samples were prepared by fusing the mixture of their respective reagent grade powders in a platinum cricuble at 750 degrees C for 30 min. DTA curves taken in the 23-600 degrees C temperature range with a heating rate of 10 degrees C/min reveal a change in the value of the glass transition temperature, Tg, while melting was not observed for the glasses containing LiCl content less than 50 mol.%. These glasses were found to be moisture-resistant. However, the glasses with LiCl content higher than 50 mol.%, in which a melting peak was observed at Tc = 401 degrees C, were moisture-sensitive. Absorption measurements in the UV/VIS region of the glasses without Tm2O3 content show that the Urbach cutoff occurs at about 320 nm and, is relatively independent of the LiCl content. Six absorption bands were observed in the Tm2O3 doped glasses corresponding to the absorption of the 1G4, 3F2, 3F3 and 3F4, 3H5 and 3H4 levels from the 3H6 ground level of Tm3+ ions. The spectra also show that the integrated absorption cross-section of each band depends on the glass composition. Judd-Ofelt theory was used to determine the Judd-Ofelt parameters as well as the radiative transition probabilities for the metastable levels of Tm3+ ions in (0.3)LiCl + (0.7) TeO2: 0.01 Tm2O3 glass which is moisture-resistant.

  2. 40 CFR 30.42 - Codes of conduct.

    Science.gov (United States)

    2010-07-01

    ... NON-PROFIT ORGANIZATIONS Post-Award Requirements Procurement Standards § 30.42 Codes of conduct. The..., recipients may set standards for situations in which the financial interest is not substantial or the gift is...

  3. Assembly Bow Characteristics of the HIPER16TM Fuel Design

    International Nuclear Information System (INIS)

    Jeon, Sang-Youn; Kwon, O-Cheol; Ha, Dong-Geun; Kim, Jae-Ik

    2015-01-01

    The out-of-pile tests were performed either in air or in a hydraulic loop and at room temperature or operating temperature conditions. The test results include the required physical and thermal-hydraulic data needed to verify the HIPER16 TM fuel design. The mechanical integrity and safety of HIPER16 TM fuel design has been verified based on the final verification tests and evaluations. The visual examinations and dimensional measurements were performed on the LTAs using poolside examination equipment. The in-reactor verification test results showed that the HIPER16 TM fuel design met the irradiation related design requirement. The poolside examinations after 3rd irradiation cycle of LTA will be performed in the end of 2015.

  4. The Ecological Controls on the Prevalence of Candidate Division TM7 in Polar Regions

    Directory of Open Access Journals (Sweden)

    Tristrom eWinsley

    2014-07-01

    Full Text Available The candidate division TM7 is ubiquitous and yet uncultured phylum of the Bacteria that encompasses a commonly environmental associated clade, TM7-1, and a ‘host-associated’ clade, TM7-3. However, as members of the TM7 phylum have not been cultured, little is known about what differs between these two clades. We hypothesized that these clades would have different environmental niches. To test this, we used a large-scale global soil dataset, encompassing 223 soil samples, their environmental parameters and associated bacterial 16S rRNA gene sequence data. We correlated chemical, physical and biological parameters of each soil with the relative abundance of the two major classes of the phylum to deduce factors that influence the groups’ seemingly ubiquitous nature. The two classes of the phylum (TM7-1 and TM7-3 were indeed distinct from each other in their habitat requirements. A key determinant of each class’ prevalence appears to be the pH of the soil. The class TM7-1 displays a facultative anaerobic nature with correlations to more acidic soils with total iron, silicon, titanium and copper indicating a potential for siderophore production. However, the TM7-3 class shows a more classical oligotrophic, heterotroph nature with a preference for more alkaline soils, and a probable pathogenic role with correlations to extractable iron, sodium and phosphate. In addition, the TM7-3 was abundant in diesel contaminated soils highlighting a resilient nature along with a possible carbon source. In addition to this both classes had unique co-occurrence relationships with other bacterial phyla. In particular, both groups had opposing correlations to the Gemmatimonadetes phylum, with the TM7-3 class seemingly being outcompeted by this phylum to result in a negative correlation. These ecological controls allow the characteristics of a TM7 phylum preferred niche to be defined and give insight into possible avenues for cultivation of this previously

  5. Electrochemistry of thulium on inert electrodes and electrochemical formation of a Tm-Al alloy from molten chlorides

    International Nuclear Information System (INIS)

    Castrillejo, Y.; Fernandez, P.; Bermejo, M.R.; Barrado, E.; Martinez, A.M.

    2009-01-01

    The electrochemical behaviour of TmCl 3 solutions was studied in the eutectic LiCl-KCl in the temperature range 673-823 K using inert and reactive electrodes, i.e. W and Al, respectively. On an inert electrode, Tm(III) ions are reduced to metallic thulium through two consecutive steps: Tm(III) + 1e ↔ Tm(II) and Tm(II) + 2e ↔ Tm(0) The electroreduction of Tm(III) to Tm(II) was found to be quasi-reversible. The intrinsic rate constant of charge transfer, k 0 , as well as of the charge transfer coefficient, α, have been calculated by simulation of the cyclic voltammograms and logarithmic analysis of the convoluted curves. Electrocrystallization of thulium plays an important role in the electrodeposition process, being the nucleation mode affected by temperature. The diffusion coefficients of Tm(III) and Tm(II) ions have been found to be equal. The validity of the Arrhenius law was verified by plotting the variation of the logarithm of the diffusion coefficients vs. 1/T. The electrode reactions of Tm(III) solutions at an Al electrode were also investigated. The results showed that for the extraction of thulium from molten chlorides, the use of a reactive electrode made of aluminium leading to Al-Tm alloys seems to be a pertinent route. Potentiometric titrations of Tm(III) solutions with oxide donors, using a ytria stabilized zirconia electrode 'YSZE' as a pO 2- indicator electrode, have shown the formation of thulium oxychloride and thulium oxide and their corresponding solubility products have been determined at 723 K (pk s (TmOCl) = 8.0 ± 0.3 pk s (Tm 2 O 3 ) = 18.8 ± 0.7).

  6. TM4SF1 Promotes Gemcitabine Resistance of Pancreatic Cancer In Vitro and In Vivo.

    Directory of Open Access Journals (Sweden)

    Jia Cao

    Full Text Available TM4SF1 is overexpressed in pancreatic ductal adenocarcinoma (PDAC and affects the development of this cancer. Also, multidrug resistance (MDR is generally associated with tumor chemoresistance in pancreatic cancer. However, the correlation between TM4SF1 and MDR remains unknown. This research aims to investigate the effect of TM4SF1 on gemcitabine resistance in PDAC and explore the possible molecular mechanism between TM4SF1 and MDR.The expression of TM4SF1 was evaluated in pancreatic cancer cell lines and human pancreatic duct epithelial (HPDE cell lines by quantitative RT-PCR. TM4SF1 siRNA transfection was carried out using Hiperfect transfection reagent to knock down TM4SF1. The transcripts were analyzed by quantitative RT-PCR, RT-PCR and western blotting for further study. The cell proliferation and apoptosis were obtained to investigate the sensitivity to gemcitabine of pancreatic cancer cells after silencing TM4SF1 in vitro. We demonstrated that cell signaling of TM4SF1 mediated chemoresistance in cancer cells by assessing the expression of multidrug resistance (MDR genes using quantitative RT-PCR. In vivo, we used orthotopic pancreatic tumor models to investigate the effect of proliferation after silencing TM4SF1 by a lentivirus-mediated shRNA in MIA PaCa-2 cell lines.The mRNA expression of TM4SF1 was higher in seven pancreatic cancer cell lines than in HPDE cell lines. In three gemcitabine-sensitive cell lines (L3.6pl, BxPC-3, SU86.86, the expression of TM4SF1 was lower than that in four gemcitabine-resistant cell lines (MIA PaCa-2, PANC-1, Hs766T, AsPC-1. We evaluated that TM4SF1 was a putative target for gemcitabine resistance in pancreatic cancer cells. Using AsPC-1, MIA PaCa-2 and PANC-1, we investigated that TM4SF1 silencing affected cell proliferation and increased the percentages of cell apoptosis mediated by treatment with gemcitabine compared with cells which were treated with negative control. This resistance was associated

  7. Functional properties of Virus-Encoded and Virus-Regulated 7TM Receptors

    DEFF Research Database (Denmark)

    Spiess, Katja; Rosenkilde, Mette Marie

    2014-01-01

    During co-evolution with their hosts, viruses have developed several survival strategies that involve exploitation of 7TM receptors. These include virus-encoded 7TM receptors and ligands and viral regulation of endogenous receptors. Many functional properties have been ascribed to virus-exploited...

  8. Changed membrane integration and catalytic site conformation are two mechanisms behind the increased Aβ42/Aβ40 ratio by presenilin 1 familial Alzheimer-linked mutations

    Directory of Open Access Journals (Sweden)

    Johanna Wanngren

    2014-01-01

    Full Text Available The enzyme complex γ-secretase generates amyloid β-peptide (Aβ, a 37–43-residue peptide associated with Alzheimer disease (AD. Mutations in presenilin 1 (PS1, the catalytical subunit of γ-secretase, result in familial AD (FAD. A unifying theme among FAD mutations is an alteration in the ratio Aβ species produced (the Aβ42/Aβ40 ratio, but the molecular mechanisms responsible remain elusive. In this report we have studied the impact of several different PS1 FAD mutations on the integration of selected PS1 transmembrane domains and on PS1 active site conformation, and whether any effects translate to a particular amyloid precursor protein (APP processing phenotype. Most mutations studied caused an increase in the Aβ42/Aβ40 ratio, but via different mechanisms. The mutations that caused a particular large increase in the Aβ42/Aβ40 ratio did also display an impaired APP intracellular domain (AICD formation and a lower total Aβ production. Interestingly, seven mutations close to the catalytic site caused a severely impaired integration of proximal transmembrane/hydrophobic sequences into the membrane. This structural defect did not correlate to a particular APP processing phenotype. Six selected FAD mutations, all of which exhibited different APP processing profiles and impact on PS1 transmembrane domain integration, were found to display an altered active site conformation. Combined, our data suggest that FAD mutations affect the PS1 structure and active site differently, resulting in several complex APP processing phenotypes, where the most aggressive mutations in terms of increased Aβ42/Aβ40 ratio are associated with a decrease in total γ-secretase activity.

  9. First principles study of structural, electronic, magnetic and elastic properties of Mg{sub 0.75}TM{sub 0.25}S (TM=Mn, Fe, Co, Ni)

    Energy Technology Data Exchange (ETDEWEB)

    Gous, M.H., E-mail: gousph@hotmail.fr; Meddour, A., E-mail: a_meddour@yahoo.fr; Bourouis, Ch., E-mail: bourouisse_ch@yahoo.fr

    2017-01-15

    The objective of this work is to predict the structural, electronic, magnetic and elastic properties of Mg{sub 1−x}TM{sub x}S (TM=Mn, Fe, Co and Ni) compound in the zinc blende Ferromagnetic phase using first principal approach. The structural and elastic properties are performed using the generalized gradient approximation proposed by Wu and Cohen(WC-GGA). However, the electronic and magnetic properties have been performed using modified Becke-Johnson potential combined with the LDA correlation (mBJLDA). The results show that all compounds Mg{sub 1−x}Mn{sub x}S, Mg{sub 1−x}Fe{sub x}S and Mg{sub 1−x}Ni{sub x}S exhibit a half-metallic ferromagnetic character with 100% spin-polarization at the Fermi level, except Mg{sub 1−x}Co{sub x}S is a metal. For each compounds study here, the total magnetic momentum is an integer equal to magnetic moments of TM atom in their free space charge value. Due to the p–d hybridization, there is a small local magnetic moment on the Mg and S sites; whereas, the local magnetic moments of TM atom reduce from their free space charge value. In addition, we investigate the mechanical behavior of MgS and Mg{sub 1−x}TM{sub x}S; all compounds studied here are mechanically stable and exhibit a strong anisotropic behavior. - Highlights: • Our results could be a prediction for coming works. • According to our results of electronic properties: Mg{sub 0.75}Co{sub 0.25}S is metal. Mg{sub 0.75}Mn{sub 0.25}S, Mg{sub 0.75}Fe{sub 0.25}S and Mg{sub 0.75}Ni{sub 0.25}S exhibit half-metallic ferromagnetic behavior with 100% spin polarization at Fermi level. • We found that MgS and Mg{sub 0.75}TM{sub 0.25}S (TM=Mn, Fe, Co and Ni) compounds are mechanically stable, ductile materials and have an anisotropic Young's Modulus. • It is likely that these materials have a high Curie temperature.

  10. Does the use of Nintendo Wii SportsTM improve arm function? Trial of WiiTM in Stroke: a randomized controlled trial and economics analysis.

    Science.gov (United States)

    Adie, Katja; Schofield, Christine; Berrow, Margie; Wingham, Jennifer; Humfryes, John; Pritchard, Colin; James, Martin; Allison, Rhoda

    2017-02-01

    The Trial of Wii™ in Stroke investigated the efficacy of using the Nintendo Wii Sports™ (Wii TM ) to improve affected arm function after stroke. Multicentre, pragmatic, parallel group, randomized controlled trial. Home-based rehabilitation. A total of 240 participants aged 24-90 years with arm weakness following a stroke within the previous six months. Participants were randomly assigned to exercise daily for six weeks using the Wii TM or arm exercises at home. Primary outcome was change in the affected arm function at six weeks follow-up using the Action Research Arm Test. Secondary outcomes included occupational performance, quality of life, arm function at six months and a cost effectiveness analysis. The study was completed by 209 participants (87.1%). There was no significant difference in the primary outcome of affected arm function at six weeks follow-up (mean difference -1.7, 95% CI -3.9 to 0.5, p = 0.12) and no significant difference in secondary outcomes, including occupational performance, quality of life or arm function at six months, between the two groups. No serious adverse events related to the study treatment were reported. The cost effectiveness analysis showed that the Wii TM was more expensive than arm exercises £1106 (SD 1656) vs. £730 (SD 829) (probability 0.866). The trial showed that the Wii TM was not superior to arm exercises in home-based rehabilitation for stroke survivors with arm weakness. The Wii TM was well tolerated but more expensive than arm exercises.

  11. Growth and optical properties of Tm:GdVO4 single crystal

    International Nuclear Information System (INIS)

    Urata, Y.; Akagawa, K.; Wada, S.; Tashiro, H.; Fukuda, T.

    1999-01-01

    Thulium-doped gadolinium vanadate (Tm:GdVO 4 ) single crystal has been successfully grown by a modified Czochralski (CZ) technique. Effective distribution coefficient of Tm was determined to be 0.74. Absorption characterization was performed in the 800 nm region and the maximum absorption peak was found at 799 nm for π polarization. Fluorescence spectra for tuning at the maximum absorption were obtained around 1.8-2.0 μm region with 100 nm bandwidth. This suggests that a Tm:GdVO 4 crystal is expected as a new promising LD pumped solid-state laser in the 2 μm region. (orig.)

  12. Yb3+ sensitized Tm3+ upconversion in tellurite lead oxide glass.

    Science.gov (United States)

    Mohanty, Deepak Kumar; Rai, Vineet Kumar; Dwivedi, Y

    2012-04-01

    Triply ionized thulium/thulium--ytterbium doped/codoped TeO2-Pb3O4 (TPO) glasses have been fabricated by classical quenching method. The upconversion emission spectra in the Tm3+/Tm3+-Yb3+ doped/codoped glasses upon excitation with a diode laser lasing at ∼980 nm has been studied. Effect of the addition of the Yb3+ on the upconversion emission intensity in the visible and near infrared regions of the Tm3+ doped in TPO glass has been studied and the processes involved explored. Copyright © 2011 Elsevier B.V. All rights reserved.

  13. NIR upconversion emission of Tm{sup 3+} doped glassceramics for solar cells applications

    Energy Technology Data Exchange (ETDEWEB)

    Rodríguez-Mendoza, U.R., E-mail: urguez@ull.edu.es [Departamento de Física, Universidad de La Laguna, 38200 San Cristóbal de La Laguna, Santa Cruz de Tenerife (Spain); Instituto Universitario de Materiales y Nanotecnología, Universidad de La Laguna, 38200 San Cristóbal de La Laguna, Santa Cruz de Tenerife (Spain); Lahoz, F. [Departamento de Física, Universidad de La Laguna, 38200 San Cristóbal de La Laguna, Santa Cruz de Tenerife (Spain); Instituto Universitario de Estudios Avanzados en Atómica, Molecular y Fotónica, Universidad de La Laguna, 38200 San Cristóbal de La Laguna, Santa Cruz de Tenerife (Spain)

    2016-11-15

    The Tm{sup 3+} 800 nm upconversion emission corresponding to the {sup 3}H{sub 4}→{sup 3}H{sub 6} transition has been obtained upon infrared sub-Si bandgap excitation at 1210 nm in Tm{sup 3+} doped transparent glasses and glass ceramics with composition SiO{sub 2}–Al{sub 2}O{sub 3}–CdF{sub 2}–PbF{sub 2}–YF{sub 3}. Possible energy transfer mechanisms have been carefully studied through different experimental measurements such as the excitation spectrum, decay rate of the emission and laser pump power versus integrated emission. The results suggest that energy transfer upconversion (ETU) mechanism is responsible for the emission. It is based on the following process: Tm{sup 3+}({sup 3}F{sub 4})+Tm{sup 3+}({sup 3}F{sub 4})→Tm{sup 3+}({sup 3}H{sub 6})+Tm{sup 3+}({sup 3}H{sub 4}). The upconverted emission is about three times more intense in the glass ceramic samples than in the precursor glasses. This emission can be used to enhance the performances in crystalline silicon (c-Si) solar cells.

  14. Energy transfer characteristics of silicate glass doped with Er{sup 3+}, Tm{sup 3+}, and Ho{sup 3+} for ∼2 μm emission

    Energy Technology Data Exchange (ETDEWEB)

    Li, Ming; Liu, Xueqiang [Key Laboratory of Materials for High Power Laser, Shanghai Institute of Optics and Fine Mechanics, Chinese Academy of Sciences, Shanghai 201800 (China); Graduate School of Chinese Academy of Sciences, Beijing 100039 (China); Guo, Yanyan [College of Materials Science and Engineering, Changchun University of Science and Technology, Changchun 130022 (China); Hu, Lili [Key Laboratory of Materials for High Power Laser, Shanghai Institute of Optics and Fine Mechanics, Chinese Academy of Sciences, Shanghai 201800 (China); Zhang, Junjie [College of Materials Science and Engineering, China Jiliang University, Hangzhou 310 018 (China)

    2013-12-28

    A Er{sup 3+}/Tm{sup 3+}/Ho{sup 3+} tri-doped silicate glass with good thermal stability is prepared by melt-quenching method. Efficient ∼2 μm emission is observed under 808 nm laser excitation. It is found that the 2.0 μm emission of Ho{sup 3+} can be enhanced under the excitation at 808 nm by incorporating Er{sup 3+} and Tm{sup 3+}. Based on the measurement of absorption spectra, the Judd–Ofelt intensity parameters, radiation emission probability, and branching ratio are calculated to evaluate the spectroscopic properties simultaneously. The maximum value of emission cross section of Ho{sup 3+} is 3.54 × 10{sup −21} cm{sup 2} at 2008 nm. Additionally, the phonon assistance and the micro-parameters in the energy transfer process are quantitatively analyzed by using Dexter model. The energy transfer coefficient from Tm{sup 3+} to Ho{sup 3+} can reach as high as 21.44 × 10{sup −40} cm{sup 6}/s, respectively. The emission property together with good thermal property indicates that Er{sup 3+}/Tm{sup 3+}/Ho{sup 3+} tri-doped silicate glass is a potential kind of laser glass for efficient 2 μm laser.

  15. Studies on the method of producing radiographic 170Tm source

    International Nuclear Information System (INIS)

    Maeda, Sho

    1976-08-01

    A method of producing radiographic 170 Tm source has been studied, including target preparation, neutron irradiation, handling of the irradiated target in the hot cell and source capsules. On the basis of the results, practical 170 Tm radiographic sources (29 -- 49Ci, with pellets 3mm in diameter and 3mm long) were produced in trial by neutron irradiation with the JMTR. (auth.)

  16. Response of TLD-100"T"M microtubes to two RQR3 quality radiation beams

    International Nuclear Information System (INIS)

    Nunes, M.G.; Villani, D.; Almeida, S.B.; Vivolo, V.; Yoriyaz, H.; Louis, G.M.J.

    2016-01-01

    The present work compares the response of TLD-100"T"M microcubes to two RQR 3 diagnostic radiology reference quality radiation beams, defined by IEC-61267 norm, aiming to evaluate the detectability of TLD-100"T"M energy dependence reported in literature within the same reference quality radiation range. TLD-100"T"M microcubes reproducibility is assessed through the response of a second set of TLD-100"T"M microcubes, evaluated in a second thermoluminescence reader, to the RQR 3 diagnostic radiology reference quality radiation beam implemented at the Laboratorio de Calibracao de Instrumentos of IPEN, Sao Paulo, SP, Brazil. The dependence of TLD-100"T"M microcubes TL response was not detectable in these conditions and the reproducibility of the measurements is 90,2%. (author)

  17. Extremely large magnetoresistance and electronic structure of TmSb

    Science.gov (United States)

    Wang, Yi-Yan; Zhang, Hongyun; Lu, Xiao-Qin; Sun, Lin-Lin; Xu, Sheng; Lu, Zhong-Yi; Liu, Kai; Zhou, Shuyun; Xia, Tian-Long

    2018-02-01

    We report the magnetotransport properties and the electronic structure of TmSb. TmSb exhibits extremely large transverse magnetoresistance and Shubnikov-de Haas (SdH) oscillation at low temperature and high magnetic field. Interestingly, the split of Fermi surfaces induced by the nonsymmetric spin-orbit interaction has been observed from SdH oscillation. The analysis of the angle-dependent SdH oscillation illustrates the contribution of each Fermi surface to the conductivity. The electronic structure revealed by angle-resolved photoemission spectroscopy (ARPES) and first-principles calculations demonstrates a gap at the X point and the absence of band inversion. Combined with the trivial Berry phase extracted from SdH oscillation and the nearly equal concentrations of electron and hole from Hall measurements, it is suggested that TmSb is a topologically trivial semimetal and the observed XMR originates from the electron-hole compensation and high mobility.

  18. Systemic GLIPR1-ΔTM protein as a novel therapeutic approach for prostate cancer.

    Science.gov (United States)

    Karantanos, Theodoros; Tanimoto, Ryuta; Edamura, Kohei; Hirayama, Takahiro; Yang, Guang; Golstov, Alexei A; Wang, Jianxiang; Kurosaka, Shinji; Park, Sanghee; Thompson, Timothy C

    2014-04-15

    GLIPR1 is a p53 target gene known to be downregulated in prostate cancer, and increased endogenous GLIPR1 expression has been associated with increased production of reactive oxygen species, increased apoptosis, decreased c-Myc protein levels and increased cell cycle arrest. Recently, we found that upregulation of GLIPR1 in prostate cancer cells increases mitotic catastrophe through interaction with heat shock cognate protein 70 (Hsc70) and downregulation of Aurora kinase A and TPX2. In this study, we evaluated the mechanisms of recombinant GLIPR1 protein (glioma pathogenesis-related protein 1-transmembrane domain deleted [GLIPR1-ΔTM]) uptake by prostate cancer cells and the efficacy of systemic GLIPR1-ΔTM administration in a prostate cancer xenograft mouse model. GLIPR1-ΔTM was selectively internalized by prostate cancer cells, leading to increased apoptosis through reactive oxygen species production and to decreased c-Myc protein levels. Interestingly, GLIPR1-ΔTM was internalized through clathrin-mediated endocytosis in association with Hsc70. Systemic administration of GLIPR1-ΔTM significantly inhibited VCaP xenograft growth. GLIPR1-ΔTM showed no evidence of toxicity following elimination from mouse models 8 hr after injection. Our results demonstrate that GLIPR1-ΔTM is selectively endocytosed by prostate cancer cells, leading to increased reactive oxygen species production and apoptosis, and that systemic GLIPR1-ΔTM significantly inhibits growth of VCaP xenografts without substantial toxicity. © 2013 UICC.

  19. Avaliação da transmissão de dados de temperatura no sistema 1-wireTM Evaluation of the temperature data transmission in the 1-wireTM system

    Directory of Open Access Journals (Sweden)

    Antonio J. Steidle Neto

    2005-04-01

    Full Text Available A necessidade de sistemas de monitoramento automático versáteis e de baixo custo que possam auxiliar o produtor agrícola na otimização dos processos produtivos, é evidente. Este trabalho foi realizado com o objetivo de pesquisar as limitações e as potencialidades de aplicação do sistema 1-wireTM na transmissão de dados de temperatura em instalações agrícolas. O sistema 1-wireTM é uma rede de transmissão de dados que possibilita a comunicação digital entre um computador e dispositivos da série 1-wireTM, tais como os sensores de temperatura DS1820. A transmissão de dados de temperatura nesse sistema foi avaliada em função do tipo dos condutores e do número de sensores DS1820. Com base nos resultados, concluiu-se que o aumento do número de sensores de temperatura DS1820 no sistema 1-wireTM incrementa a carga capacitiva de maneira distinta para cada um dos tipos de condutores estudados, podendo causar interrupções na transmissão de dados.The need of versatile and low cost automatic monitoring systems for the optimization of the agricultural productive processes is evident. This work was carried out to evaluate the limitations and potentialities of the 1-wireTM system for temperature data transmission in agricultural buildings. The 1-wireTM system is a data transmission network, which makes possible the digital communication between a computer and devices of the 1-wireTM series, such as the temperature DS1820 sensors. The temperature data transmission in this system was evaluated as a function of types of conductors and the number of DS1820 sensors. Based on the results, it was concluded that, by increasing the number of the DS1820 temperature sensors in the 1-wireTM system, the capacitive load increases in a different way for each conductor and can cause interruptions during temperature data transmission.

  20. Comparison of hyperspectral transformation accuracies of multispectral Landsat TM, ETM+, OLI and EO-1 ALI images for detecting minerals in a geothermal prospect area

    Science.gov (United States)

    Hoang, Nguyen Tien; Koike, Katsuaki

    2018-03-01

    Hyperspectral remote sensing generally provides more detailed spectral information and greater accuracy than multispectral remote sensing for identification of surface materials. However, there have been no hyperspectral imagers that cover the entire Earth surface. This lack points to a need for producing pseudo-hyperspectral imagery by hyperspectral transformation from multispectral images. We have recently developed such a method, a Pseudo-Hyperspectral Image Transformation Algorithm (PHITA), which transforms Landsat 7 ETM+ images into pseudo-EO-1 Hyperion images using multiple linear regression models of ETM+ and Hyperion band reflectance data. This study extends the PHITA to transform TM, OLI, and EO-1 ALI sensor images into pseudo-Hyperion images. By choosing a part of the Fish Lake Valley geothermal prospect area in the western United States for study, the pseudo-Hyperion images produced from the TM, ETM+, OLI, and ALI images by PHITA were confirmed to be applicable to mineral mapping. Using a reference map as the truth, three main minerals (muscovite and chlorite mixture, opal, and calcite) were identified with high overall accuracies from the pseudo-images (> 95% and > 42% for excluding and including unclassified pixels, respectively). The highest accuracy was obtained from the ALI image, followed by ETM+, TM, and OLI images in descending order. The TM, OLI, and ALI images can be alternatives to ETM+ imagery for the hyperspectral transformation that aids the production of pseudo-Hyperion images for areas without high-quality ETM+ images because of scan line corrector failure, and for long-term global monitoring of land surfaces.

  1. Coevolution and hierarchical interactions of Tomato mosaic virus and the resistance gene Tm-1.

    Directory of Open Access Journals (Sweden)

    Kazuhiro Ishibashi

    Full Text Available During antagonistic coevolution between viruses and their hosts, viruses have a major advantage by evolving more rapidly. Nevertheless, viruses and their hosts coexist and have coevolved, although the processes remain largely unknown. We previously identified Tm-1 that confers resistance to Tomato mosaic virus (ToMV, and revealed that it encodes a protein that binds ToMV replication proteins and inhibits RNA replication. Tm-1 was introgressed from a wild tomato species Solanum habrochaites into the cultivated tomato species Solanum lycopersicum. In this study, we analyzed Tm-1 alleles in S. habrochaites. Although most part of this gene was under purifying selection, a cluster of nonsynonymous substitutions in a small region important for inhibitory activity was identified, suggesting that the region is under positive selection. We then examined the resistance of S. habrochaites plants to ToMV. Approximately 60% of 149 individuals from 24 accessions were resistant to ToMV, while the others accumulated detectable levels of coat protein after inoculation. Unexpectedly, many S. habrochaites plants were observed in which even multiplication of the Tm-1-resistance-breaking ToMV mutant LT1 was inhibited. An amino acid change in the positively selected region of the Tm-1 protein was responsible for the inhibition of LT1 multiplication. This amino acid change allowed Tm-1 to bind LT1 replication proteins without losing the ability to bind replication proteins of wild-type ToMV. The antiviral spectra and biochemical properties suggest that Tm-1 has evolved by changing the strengths of its inhibitory activity rather than diversifying the recognition spectra. In the LT1-resistant S. habrochaites plants inoculated with LT1, mutant viruses emerged whose multiplication was not inhibited by the Tm-1 allele that confers resistance to LT1. However, the resistance-breaking mutants were less competitive than the parental strains in the absence of Tm-1. Based on

  2. High temperature phase transition of Tm2Ti2O7

    International Nuclear Information System (INIS)

    Shlyakhtina, A.V.; Shcherbakova, L.G.; Knot'ko, A.V.; Larina, L.L.; Borichev, S.A.

    2004-01-01

    A high temperature phase transition type order-disorder is investigated in Tm 2 Ti 2 O 7 at t>1600 Deg C. It is shown that this transformation is irreversible. Ion conductivity of synthesized at 1670 Deg C nanocrystalline Tm 2 Ti 2 O 7 constitutes 2x10 -3 S/cm at 740 Deg C and remains constant after heat treatment at 860 Deg C for 240 h in the air. It is revealed that the conductivity of specimens (grain size of 20-30 nm) on the basis of Tm 2 Ti 2 O 7 high temperature modification with a structure of disordered pyrochlore is independent of grain size [ru

  3. Crystal growth and characterization of Tm doped mixed rare-earth aluminum perovskite

    Energy Technology Data Exchange (ETDEWEB)

    Totsuka, Daisuke, E-mail: totsuka@imr.tohoku.ac.jp [Institute for Materials Research, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai, Miyagi 980-8577 (Japan); Nihon Kessho Kogaku Co., Ltd., 810-5 Nobe-cho, Tatebayashi, Gunma 374-0047 (Japan); Yanagida, Takayuki [New Industry Creation Hatchery Center (NICHe), 6-6-10 Aoba, Aramaki, Aoba-ku, Sendai, Miyagi 980-8579 (Japan); Sugiyama, Makoto; Fujimoto, Yutaka; Yokota, Yuui [Institute for Materials Research, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai, Miyagi 980-8577 (Japan); Yoshikawa, Akira [Institute for Materials Research, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai, Miyagi 980-8577 (Japan); New Industry Creation Hatchery Center (NICHe), 6-6-10 Aoba, Aramaki, Aoba-ku, Sendai, Miyagi 980-8579 (Japan)

    2012-04-15

    Highlights: Black-Right-Pointing-Pointer (Lu{sub x}Gd{sub y}Y{sub 0.99-x-y}Tm{sub 0.01})AP single crystals were grown by the {mu}-PD method. Black-Right-Pointing-Pointer The grown crystals were single phase with perovskite structure (Pbnm). Significant segregation of Lu and Gd was detected in the growth direction. Black-Right-Pointing-Pointer Some absorption bands due to Tm{sup 3+}, Gd{sup 3+} and color centers were exhibited. Black-Right-Pointing-Pointer Radioluminescence spectra showed several emission peaks ascribed to Tm{sup 3+} and Gd{sup 3+}. -- Abstract: In this work, we present results of structural characterization and optical properties including radio luminescence of (Lu{sub x}Gd{sub y}Y{sub 0.99-x-y}Tm{sub 0.01})AP single crystal scintillators for (x, y) = (0.30, 0.19), (0, 0.19) and (0, 0) grown by the micro-pulling-down ({mu}-PD) method. The grown crystals were single phase materials with perovskite structure (Pbnm) as confirmed by XRD and had a good crystallinity. The distribution of the crystal constituents in growth direction was evaluated, and significant segregation of Lu and Gd was detected in (Lu{sub 0.30}Gd{sub 0.19}Y{sub 0.50}Tm{sub 0.01})AP sample. The crystals demonstrated 70% transmittance in visible wavelength range and some absorption bands due to Tm{sup 3+}, Gd{sup 3+} and color centers were exhibited in 190-900 nm. The radioluminescence measurement under X-ray irradiation demonstrated several emission peaks ascribed to 4f-4f transitions of Tm{sup 3+} and Gd{sup 3+}. The ratio of emission intensity in longer wavelength range was increased when Y was replaced by Lu or Gd.

  4. Determination of dosimetric characteristics of OptiSeedTM a plastic brachytherapy 103Pd source

    International Nuclear Information System (INIS)

    Wang Zhonglu; Hertel, Nolan E.

    2005-01-01

    A new 103 Pd plastic brachytherapy source, OptiSeed TM Model 1032P, is being introduced by International Brachytherapy sa (IBt). Measurements of the dose distributions about the source were performed using LiF thermoluminescent dosimeters (TLD-100) in Virtual Water TM . MCNP5 calculations were performed to determine the dose distributions in Virtual Water TM and liquid water. The source dose rate constant, radial dose function, anisotropy function and anisotropy factor have been determined following the updated AAPM TG-43 recommendations. The measured dose rate constant in the Virtual Water TM phantom was determined to be 0.727±6.9% cGy h -1 U -1 , and the computed value is 0.716±2.1% cGy h -1 U -1 . The Monte-Carlo simulation yielded a dose rate constant of 0.665±2.1% cGy h -1 U -1 in water. The measured dose rate constant in water is 0.675±7.5% cGy h -1 U -1 . It is determined by multiplying the dose rate constant measured in the Virtual Water TM phantom with the ratio of the value calculated in water to that in Virtual Water TM . The average of the measured and calculated dose rate constant is 0.670±5.5% cGy h -1 U -1 . The radial dose functions of the new source were measured for distances ranging from 1 to 7 cm in a Virtual Water TM phantom. The anisotropy functions in Virtual Water TM phantom were measured for distances of 2, 3, 5, and 7 cm. The Monte-Carlo computed radial dose functions, anisotropy functions, and anisotropy factors in both Virtual Water TM phantom and water are reported

  5. KevlarTM Fiber-Reinforced Polybenzoxazine Alloys for Ballistic Impact Application

    Directory of Open Access Journals (Sweden)

    Chanchira Jubsilp

    2011-10-01

    Full Text Available A light weight ballistic composites from KevlarTM-reinforcing fiber having polybenzoxazine (BA/urethane prepolymer (PU alloys as a matrix were investigated in this work. The effect of alloy compositions on the ballistic composite properties was determined. The results revealed that the enhancement in the glass transition temperature (Tg of the KevlarTM-reinforced BA/PU composites compared to that of the KevlarTM-reinforced polybenzoxazine composite was observed. The increase of the elastomeric PU content in the BA/PU alloy resulted in samples with tougher characteristics. The storage modulus of the KevlarTM-reinforced BA/PU composites increased with increasing the mass fraction of polybenzoxazine. A ballistic impact test was also performed on the KevlarTM-reinforced BA/PU composites using a 9 mm handgun. It was found that the optimal contents of PU in the BA/PU alloys should be approximately 20wt%. The extent of the delaminated area and interfacial fracture were observed to change with the varied compositions of the matrix alloys. The appropriate thickness of KevlarTM-reinforced 80/20 BA/PU composite panel was 30 plies and 50 plies to resist the penetration from the ballistic impact equivalent to levels II-A and III-A of NIJ standard. The arrangement of composite panels with the higher stiffness panel at the front side also showed the best efficiency of ballistic penetration resistance.

  6. Luminescence properties of Yb:Nd:Tm:KY3F10 nanophosphor and thermal treatment effects

    International Nuclear Information System (INIS)

    Gomes, Laércio; Linhares, Horácio Marconi da Silva M.D.; Ichikawa, Rodrigo Uchida; Martinez, Luis Gallego; Ranieri, Izilda Marcia

    2015-01-01

    In this work, we present the spectroscopic properties of KY 3 F 10 (KY3F) nanocrystals activated with thulium and codoped with ytterbium and neodymium ions. The most important processes that lead to the thulium upconversion emissions in the blue region were identified. A time-resolved luminescence spectroscopy technique was employed to measure the luminescence decays and to determine the most important mechanisms involved in the upconversion process that populates 1 G 4 (Tm 3+ ) excited states. Analysis of the energy-transfer processes dynamics using selective pulsed-laser excitations in Yb:Nd:Tm, Nd:KY3F nanocrystals shows that the direct energy transfer from Nd 3+ to Tm 3+ ions is the mechanism responsible for the 78% of the blue upconversion luminescence in the Yb:Nd:Tm:KY3F when compared with the Yb:Nd:Tm:KY3F bulk crystal for an laser excitation at 802 nm. An investigation of the 1 G 4 level luminescence kinetic of Tm 3+ in Yb/Nd/Tm system revealed that the luminescence efficiency ( 1 G 4 ) starts with a very low value (0.38%) for the synthesized nanocrystal (as grown) and strongly increases to 97% after thermal treatment at 550 °C for 6 h under argon flow. As a consequence of the thermal treatment at T=550 °C, the contributions of the (Nd×Tm) (Up 1 ) and (Nd×Yb×Tm) (Up 2 ) upconversion processes to the 1 G 4 luminescence are 33% (Up 1 ) and 67% for Up 2 . Up 2 process represented by Nd 3+ ( 4 F 3/2 )→Yb 3+ ( 2 F 7/2 ) followed by Yb 3+ ( 2 F 5/2 )→Tm ( 3 H 4 )→Tm 3+ ( 1 G 4 ) was previously reported as the main mechanism to produce the blue luminescence in Yb:Nd:Tm:YLiF 4 and KY 3 F 10 bulk crystals. Results of X-ray diffraction analysis of nanopowder using the Rietveld method reveled that crystallite sizes remain unchanged (12–14 nm) after thermal treatments with T≤400 °C, while the 1 G 4 luminescence efficiency strongly increases from 0.38% (T=25 °C) to 12% (T=400 °C). Results shown that the Nd 3+ ions distribution has a concentration

  7. Synthesis and characterization of KY3F10 and KY3F10:Yb:Nd:Tm crystals for optical applications

    International Nuclear Information System (INIS)

    Linhares, Horacio Marconi da Silva Dantas

    2009-01-01

    In this work, crystals of KY 3 F 10 pure and doped with Yb, Nd and Tm were grown aiming at the attainment of blue emission via Tm 3+ ions up conversion. It was established the best conditions to synthesis and purification of KY 3 F 10 . Crystals doped with 1.3 mol% Nd, 0.5 mol% Tm and some concentrations of Yb (5, 10, 20, 30 and 40 mol%) were obtained by slow cooling of the charge from the melt, using an usual conventional synthesis system and in a reactive HF atmosphere. It was taken into account parameters as cooling rate and different configurations of boats to conditioning the materials. The limit of Yb concentration to obtain a unique cubic phase was determined as 30mol%, for the cooling rates used in this work. The physical and chemical characterizations of the samples were performed by X-ray diffraction, differential thermal analysis, inductively coupled plasma-optical emission spectroscopy (ICP-OES), scanning electron microscopy, optical absorption and emission. An initial spectroscopic study was performed to verify the effect of the Yb 3+ concentration regarding the blue emission efficiency in the KY 3 F 10 :Yb:Nd:Tm. When the Nd 3+ is pumped at 797 nm, it was determined that the suitable Yb concentrations are between 10 and 20 mol% to obtain blue emission at 480 nm, and between 20 and 30 mol% to obtain emission at 450 nm. It was observed that two emissions bands in the UV (350 and 360nm) enhanced proportionally with the Yb 3+ concentration. (author)

  8. Application of Landsat 5-TM and GIS data to elk habitat studies in northern Idaho

    Science.gov (United States)

    Hayes, Stephen Gordon

    1999-12-01

    An extensive geographic information system (GIS) database and a large radiotelemetry sample of elk (n = 153) were used to study habitat use and selection differences between cow and bull elk (Cervus elaphus) in the Coeur d'Alene Mountains of Idaho. Significant sex differences in 40 ha area use, and interactive effects of sex and season on selection of 40 ha areas from home ranges were found. In all seasons, bulls used habitats with more closed canopy forest, more hiding cover, and less shrub and graminoid cover, than cows. Cows selected areas with shrub and graminoid cover in winter and avoided areas with closed canopy forest and hiding cover in winter and summer seasons. Both sexes selected 40 ha areas of unfragmented hiding cover and closed canopy forest during the hunting season. Bulls also avoided areas with high open road densities during the rut and hunting season. These results support present elk management recommendations, but our observations of sexual segregation provide biologists with an opportunity to refine habitat management plans to target bulls and cows specifically. Furthermore, the results demonstrate that hiding cover and canopy closure can be accurately estimated from Landsat 5-TM imagery and GIS soil data at a scale and resolution to which elk respond. As a result, our habitat mapping methods can be applied to large areas of private and public land with consistent, cost-efficient results. Non-Lambertian correction models of Landsat 5-TM imagery were compared to an uncorrected image to determine if topographic normalization increased the accuracy of elk habitat maps of forest structure in northern Idaho. The non-Lambertian models produced elk habitat maps with overall and kappa statistic accuracies as much as 21.3% higher (p < 0.0192) than the uncorrected image. Log-linear models and power analysis were used to study the dependence of commission and omission error rates on topographic normalization, vegetation type, and solar incidence angle

  9. Improvement of bio-corrosion resistance for Ti42Zr40Si15Ta3 metallic glasses in simulated body fluid by annealing within supercooled liquid region.

    Science.gov (United States)

    Huang, C H; Lai, J J; Wei, T Y; Chen, Y H; Wang, X; Kuan, S Y; Huang, J C

    2015-01-01

    The effects of the nanocrystalline phases on the bio-corrosion behavior of highly bio-friendly Ti42Zr40Si15Ta3 metallic glasses in simulated body fluid were investigated, and the findings are compared with our previous observations from the Zr53Cu30Ni9Al8 metallic glasses. The Ti42Zr40Si15Ta3 metallic glasses were annealed at temperatures above the glass transition temperature, Tg, with different time periods to result in different degrees of α-Ti nano-phases in the amorphous matrix. The nanocrystallized Ti42Zr40Si15Ta3 metallic glasses containing corrosion resistant α-Ti phases exhibited more promising bio-corrosion resistance, due to the superior pitting resistance. This is distinctly different from the previous case of the Zr53Cu30Ni9Al8 metallic glasses with the reactive Zr2Cu phases inducing serious galvanic corrosion and lower bio-corrosion resistance. Thus, whether the fully amorphous or partially crystallized metallic glass would exhibit better bio-corrosion resistance, the answer would depend on the crystallized phase nature. Copyright © 2015 Elsevier B.V. All rights reserved.

  10. Application of shell model with the modified surface delta interaction to 42Ca and 42Sc nuclei

    International Nuclear Information System (INIS)

    Jasielska, A.; Wiktor, S.

    1975-01-01

    The shell model with MSDI residual interaction is used to investigate properties of levels in the 42 Ca and 42 Sc nuclei. The 40 Ca core with two active outer nucleons is assumed. The energy matrices are diagonalized and the calculated level schemes for both 42 Ca and 42 Sc nuclei are presented. In both nuclei the density of the calculated levels is significantly less than of the observed levels. This fact leads to the conclusion, that some core excitation modes play an important role in the formation of low-lying states in the 42 Ca and 42 Sc nuclei. The calculated eigenvalues and eigenvectors of the states below 5 MeV are given. (author)

  11. A diode-pumped Tm:CaYAlO4 laser at 1851 nm

    Science.gov (United States)

    Lan, Jinglong; Guan, Xiaofeng; Xu, Bin; Moncorgé, Richard; Xu, Huiying; Cai, Zhiping

    2017-07-01

    Laser emission at ~1850 nm is of great interest for neural stimulation applications. In this letter, we report on the diode-pumped continuous-wave (CW) and Q-switched (QS) laser operation of Tm:CaYAlO4 at 1851 nm, for the first time to our knowledge. In the CW regime, a maximum output power up to 0.62 W is obtained with a laser slope efficiency of about 18.0%. Using a Cr:ZnSe saturable absorber, QS laser operation is achieved with a maximum average output power of 0.25 W, the narrowest pulse width of 107 ns and the highest repetition rate of 5.85 kHz. The corresponding pulse peak power and pulse energy are about 388 W and 42.8 µJ, respectively. In this Q-switched mode, wavelength tuning is also realized over about 3 nm by slightly tilting the saturable absorber.

  12. Magnetism, structures and stabilities of cluster assembled TM@Si nanotubes (TM = Cr, Mn and Fe): a density functional study.

    Science.gov (United States)

    Dhaka, Kapil; Bandyopadhyay, Debashis

    2016-08-02

    The present study reports transition metal (TM = Cr, Mn and Fe) doped silicon nanotubes with tunable band structures and magnetic properties by careful selection of cluster assemblies as building blocks using the first-principles density functional theory. We found that the transition metal doping and in addition, the hydrogen termination process can stabilize the pure silicon nanoclusters or cluster assemblies and then it could be extended as magnetic nanotubes with finite magnetic moments. Study of the band structures and density of states (DOS) of different empty and TM doped nanotubes (Type 1 to Type 4) show that these nanotubes are useful as metals, semiconductors, semi-metals and half-metals. These designer magnetic materials could be useful in spintronics and magnetic devices of nanoscale order.

  13. Diode-pumped laser performance of Tm:Sc2SiO5 crystal at 1971 nm

    International Nuclear Information System (INIS)

    Liu Bin; Wang Qing-Guo; Tang Hui-Li; Wu Feng; Luo Ping; Zhao Heng-Yu; Shi Jiao-Jiao; He Nuo-Tian; Li Na; Li Qiu; Guo Chao; Wang Zhan-Shan; Xu Jun; Zheng Li-He; Su Liang-Bi; Liu Jun-Fang; Liu Jie; Fan Xiu-Wei; Xu Xiao-Dong

    2017-01-01

    The 4-at.% Tm:Sc 2 SiO 5 (Tm:SSO) crystal is successfully obtained by the Czochralski method. The optical properties and thermal conductivity of the crystal are investigated. The broad continuous wave (CW) laser output of (100)-cut Tm:SSO with the dimensions of 3 mm× 3 mm× 3 mm under laser diode (LD)-pumping is realized. The full width at half maximum (FWHM) of the laser emitting reaches up to 21 nm. The laser threshold of Tm:SSO is measured to be 0.43 W. Efficient diode-pumped CW laser performance of Tm:SSO is demonstrated with a slope efficiency of 25.9% and maximum output power of 934 mW. (paper)

  14. Seroepidemiology of TmPV1 infection in captive and wild Florida manatees (Trichechus manatus latirostris).

    Science.gov (United States)

    Donà, Maria Gabriella; Rehtanz, Manuela; Adimey, Nicole M; Bossart, Gregory D; Jenson, Alfred B; Bonde, Robert K; Ghim, Shin-je

    2011-07-01

    In 1997, cutaneous papillomatosis caused by Florida manatee (Trichechus manatus latirostris [Tm]) papillomavirus 1 (TmPV1) was detected in seven captive manatees at the Homosassa Springs Wildlife State Park, Florida, USA, and, subsequently, in two wild manatees from the adjacent Homosassa River. Since then, papillomatosis has been reported in captive manatees housed in other locations, but not in wild animals. To determine TmPV1 antibody prevalence in captive and wild manatees sampled at various locations throughout Florida coastal regions, virus-like particles, composed of the L1 capsid protein of TmPV1, were generated with a baculovirus expression system and used to measure anti-TmPV1 antibodies in an enzyme-linked immunosorbent assay. Serologic analysis of 156 manatees revealed a TmPV1 antibody prevalence of 26.3%, with no significant difference between captive (n=39) and wild (n=117) manatees (28.2% and 25.6%, respectively). No antibody-positive wild animal showed PV-induced cutaneous lesions, whereas papillomatosis was observed in 72.7% of antibody-positive captive manatees. Our data indicate that Florida manatees living in the wild are naturally infected by TmPV1 but rarely show TmPV1-induced papillomatosis. Hence, it appears that the wild population would not be harmed in a case of contact with captive animals without visible lesions and productive infections, which could be thus released into the wild.

  15. Tm:GGAG crystal for 2μm tunable diode-pumped laser

    Science.gov (United States)

    Šulc, Jan; Boháček, Pavel; Němec, Michal; Fibrich, Martin; Jelínková, Helena; Trunda, Bohumil; Havlák, Lubomír.; Jurek, Karel; Nikl, Martin

    2016-04-01

    The spectroscopy properties and wavelength tunability of diode pumped laser based on Tm-doped mixed gadolinium-gallium-aluminium garnet Gd3(GaxAl1-x)5O12 (Tm:GGAG) single crystal were investigated for the first time. The crystal was grown by Czochralski method in a slightly oxidative atmosphere using an iridium crucible. The tested Tm:GGAG sample was cut from the grown crystal boule perpendicularly to growth direction (c-axis). The composition of sample was determined using electron microprobe X-ray elemental analysis. For spectroscopy and laser experiments 3.5mm thick plane-parallel face-polished plate (without AR coatings) with composition Gd2.76Tm0.0736Ga2.67Al2.50O12 (2.67 at.% Tm/Gd) was used. A fiber (core diameter 400 μm, NA= 0.22) coupled laser diode (emission wavelength 786 nm) was used for longitudinal Tm:GGAG pumping. The laser diode was operating in the pulsed regime (10 ms pulse length, 10 Hz repetition rate, maximum power amplitude 18 W). The 145mm long semi-hemispherical laser resonator consisted of a flat pumping mirror (HR @ 1.8- 2.10 μm, HT @ 0.78 μm) and curved (r = 150mm) output coupler with a reflectivity of » 97% @ 1.8- 2.10 µm. The maximum laser output power amplitude 1.14W was obtained at wavelength 2003nm for absorbed pump power amplitude 4.12W. The laser slope efficiency was 37% in respect to absorbed pumping power. Wavelength tuning was accomplished by using 2mm thick MgF2 birefringent filter placed inside the laser resonator at the Brewster angle. The laser was continuously tunable over 180nm in a spectral region from 1856nm to 2036 nm.

  16. Anomalous dispersion properties of TM waves in subwavelength metallic waveguides loaded by uniaxial metamaterials

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Guanghui, E-mail: wanggh@scnu.edu.cn; Lei, Yuandong; Zhang, Weifeng

    2015-02-20

    Dispersion properties of transverse magnetic (TM) waves in a subwavelength metallic waveguide loaded by uniaxial metamaterials are investigated, based on two kinds of uniaxial metamaterials with different orientations of optical axis. The numerical results show that the existence of fundamental TM{sub 0} mode and high-order TM modes in the waveguide system is dependent on the orientation of optical axis. In addition, their anomalous dispersion properties are clarified. When the orientation of optical axis is selected properly, there are two branches of dispersion curves for each high-order mode—one is normal dispersion and another belongs to anomalous dispersion, showing a transition from a backward wave to a forward one with the increase of working frequency. Moreover, the group velocity and energy flow distribution for TM{sub 1} mode are also demonstrated. These properties may have potential applications in optical information storage, integrated optics and nanophotonic devices. - Highlights: • Two kinds of subwavelength uniaxial metamaterial waveguides are constructed. • We demonstrate anomalous dispersion properties of transverse magnetic (TM) guided modes. • There are two branches of dispersion curves for high-order TM modes, showing a transition from a backward wave to a forward one. • Group velocity can approach to zero, having potential application in optical information storage. • Negative group velocity and energy flow distribution for TM modes are shown.

  17. Dosimetric properties of Li2 B4 O7: Tm pellets

    International Nuclear Information System (INIS)

    Rzyski, B.M.; Morato, S.P.

    1987-10-01

    Pellets produced out of thulium doped lithium tetraborate, (Li 2 B 4 O 7 :Tm), for thermoluminescent, (TL), dosimetry present low sensibility to environment conditions. Humidity, ambiet temperature, fading and handling during TL reading have almost no influence on the TL properties of the pellets prepared according the receipt given in this paper. The structure of the TL glow curve for the irradiated Li 2 B 4 O 7 : Tm pellet is rather simple and the TL response is linear in the range of 3x10 -4 to 7x10 2 Gy. The dosimetric properties of Li 2 B 4 O 7 : Tm in pellet form makes it a competitor with other TL phosphors. (author) [pt

  18. Impact of Maple(TM) on the design, instruction and performance in an undergraduate physics mathematical methods course

    Science.gov (United States)

    Runge, Alan Paul

    1997-10-01

    A traditional undergraduate physics course on mathematical methods has been redesigned to incorporate the use of Maplesp{sc {TM}}, a computer algebra program, during all aspects of the course. Topics covered were: complex number theory; series approximations; matrix theory; partial differentiation; vector algebra; and vector calculus. Five undergraduate students were enrolled, from sophomore to senior in academic class standing. A qualitative case study methodology was used to describe the changes in the course design resulting from the incorporation of Maplesp{sc {TM}} and their impact on the instruction of the course, and to determine the effects on the students' learning and development of problem solving skills in physics using Maplesp{sc {TM}} as a problem solving tool. The impact of using Maplesp{sc {TM}} on the number and types of interactions is presented. The entire semester long course was included in this study. Each class session is described in detail. Examples of the Maplesp{sc {TM}} materials used are given. The use of the Maplesp{sc {TM}} program was allowed on all homework and exams with each student having their own computer during class. Constraints were made so that the assessment emphasis remained on the mathematics and the conceptual understanding of the problem solving methods. All of the students demonstrated some level of proficiency in using Maplesp{TM} to solve the assigned problems. Strategies for effectively using Maplesp{TM} were presented and were individualized by the students. The students reported positive and negative impacts of using Maplesp{sc {TM}}. All of the students satisfactorily completed the course requirements, receiving final course grades from B to A+. All of them continued to voluntarily use Maplesp{sc {TM}} during the following semester. Instructional methods used included various lecture techniques without Maplesp{sc {TM}} assistance, lectures and demonstrations using only Maplesp{sc {TM}}, and student tasks

  19. Application of a UPLC–MS/MS method to the protein binding study of TM-2 in rat, human and beagle dog plasma

    Directory of Open Access Journals (Sweden)

    Hui Liu

    2016-02-01

    Full Text Available TM-2 known as a potential antitumor drug is a novel semi-synthetic taxane derivative. As drug–protein interactions contribute to insights into pharmacokinetic and pharmacodynamic properties, we elucidated the binding of TM-2 to plasma protein. In this study, a simple, rapid and reliable method was developed and validated employing equilibrium dialysis for the separation of bound and unbound drugs and ultra-performance liquid chromatography–tandem mass spectrometry (UPLC–MS/MS for the quantitation. Protein binding reached equilibrium within 24 h of incubation at 37 °C. After liquid–liquid extraction with methyl tert-butyl ether, the samples were separated on Thermo Syncronis UPLC® C18 (2.1 mm×50 mm, 1.7 µm, and acquisition of mass spectrometric data was performed in multiple reaction monitoring (MRM mode via positive electrospray ionization. The assay was linear over the concentration rang of 5–2000 ng/mL. The intra- and inter-day precisions were 0.1%–14.8%, and the accuracy was from −6.4% to 7.0%. This assay has been successfully applied to a protein binding study of TM-2 in rat, human and beagle dog plasma. TM-2 showed high protein binding of 81.4%±6.5% (rat, 87.9%±3.6% (human and 79.4%±4.0% (beagle dog. The results revealed that there was an insignificant difference among the three species.

  20. Density functional study of the stability and magnetic behaviour of Au{sub n}TM{sup +} clusters (TM=Au,Sc,Ti,V,Cr,Mn,Fe; 1{<=}n{<=}9)

    Energy Technology Data Exchange (ETDEWEB)

    Torres, M.B. [Dpto. de Matematicas y Computacion, Univ. de Burgos, Avda. de Cantabria s/n, 09006-Burgos (Spain); Fernandez, E.M.; Balbas, L.C. [Dpto. de Fisica Teorica, Univ. de Valladolid, Prado de la Magdalena s/n, 47011-Valladolid (Spain)

    2005-03-01

    We study the element- and size-dependent electron stability of Au{sub n}TM{sup +} clusters (TM=Sc,Ti,V,Cr,Mn,Fe,Au; 1{<=}n{<=}9) by means of first-principles density functional calculations. The interplay between the cluster atomic arrangements and their electronic and magnetic structure is investigated for the few lower energy isomeric-states in dependence of the TM-atom and its environment in the cluster. We explain the experimental magic-numbers, observed recently, as well as the trend of the impurity local magnetic moment in dependence with the size of the cluster and the position of the impurity in the host. (copyright 2005 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim) (orig.)

  1. Development of a 170Tm source for mercury monitoring studies in humans using XRF

    International Nuclear Information System (INIS)

    Timmaraju, K. Phanisree; Fajurally, Bibi Najah; Armstrong, Andrea F.; Chettle, David R.

    2016-01-01

    The goals of the present study were to develop a 170 Tm radioisotope and generate a K XRF spectrum of mercury. Thulium foil and thulium oxide powder were both tested for impurities and the latter was found to be a better prospect for further studies. The 170 Tm radioisotope was developed from thulium oxide powder following the method of disolution and absorption. A suitable source holder and collimator were also designed based on Monte Carlo simulations. Using the radioisotope thus developed, a mercury XRF spectrum was successfully generated. - Highlights: • We tested the purity of thulium samples by XRF and NAA techniques. • Developed a procedure to generate Tm-170 isotope out of thulium oxide powder. • Designed a collimator and source holder • Generated XRF spectrum of mercury using the Tm-170 isotope. • Compared the highlights in mercury spectra from Tm-170 and Cd-109 isotopes.

  2. Molecular mechanism of 7TM receptor activation--a global toggle switch model

    DEFF Research Database (Denmark)

    Schwartz, Thue W; Frimurer, Thomas M; Holst, Birgitte

    2006-01-01

    the accumulated biophysical data supporting an outward rigid-body movement of the intracellular segments, as well as the recent data derived from activating metal ion sites and tethered ligands, which suggests an opposite, inward movement of the extracellular segments of the transmembrane helices. According...... to this model, a vertical see-saw movement of TM-VI-and to some degree TM-VII-around a pivot corresponding to the highly conserved prolines will occur during receptor activation, which may involve the outer segment of TM-V in an as yet unclear fashion. Small-molecule agonists can stabilize such a proposed...

  3. Influence of Tm+3 concentration on the non-linear optical effects of the BiB3O6 : Tm3+ glass nanoparticle-doped polymer

    International Nuclear Information System (INIS)

    Majchrowski, A; Ebothe, J; Ozga, K; Kityk, I V; Reshak, A H; Lukasiewicz, T; Brik, M G

    2010-01-01

    It is shown that BiB 3 O 6 : Tm 3+ glass nanoparticles incorporated into polymethylmethacrylate (PMMA) and polycarbonate (PC) polymer matrices show good second-order susceptibilities under bicolour coherent laser treatment. It is found that only during incorporation into highly polarized PC matrices could one observe an enhancement of the second-order susceptibilities with increasing laser treated power densities. The main increase is observed for all samples at power densities equal to about 0.4 GW cm -2 . After passing this value there is a saturation of the output susceptibilities and even an abrupt decrease. The most striking feature is the achievement of second-order susceptibilities equal to about 5 pm V -1 for samples containing 4% nanoparticle (NP) content in the PC matrix. A further increase in the NP concentration to 6% leads to a decrease in susceptibility to 15%. In the case of PMMA matrices these changes do not exceed the background. The same situation is present for the pure BIBO and low-doped Tm materials. The effect is maximal for a low concentration of Tm-about 0.75%. In the case of bulk glasses the intensity dependences of the second-harmonic generation unambiguously show that the achieved maximal values of second-order susceptibilities do not exceed 3 pm V -1 for 0.5% Tm concentration.

  4. Effect of Tm substitution on the magnetic properties and local magnetic anisotropy of amorphous Fe80-xTm xB20 ribbons

    International Nuclear Information System (INIS)

    Sayouty, E.H.; Annouar, F.; Lassri, H.; Randrianantoandro, N.; Greneche, J.M.

    2005-01-01

    We have carried out magnetic and Moessbauer studies of amorphous Fe 80-x Tm x B 20 alloys (0 ≤ x ≤ 16). With an increasing Tm content, both the Curie temperature T C and the magnetic moment of Fe atom μ Fe decrease. We have extracted the value of exchange constant A from T C and that of the local magnetic anisotropy constant K L from the coercivity. Moessbauer studies were performed in a transmission geometry and also using the conversion electron spectroscopy. Both Moessbauer spectrometry techniques show that the average hyperfine field decreases linearly with the addition of rare-earth

  5. Modeling a Hypothetical 170Tm Source for Brachytherapy Applications

    International Nuclear Information System (INIS)

    Enger, Shirin A.; D'Amours, Michel; Beaulieu, Luc

    2011-01-01

    Purpose: To perform absorbed dose calculations based on Monte Carlo simulations for a hypothetical 170 Tm source and to investigate the influence of encapsulating material on the energy spectrum of the emitted electrons and photons. Methods: GEANT4 Monte Carlo code version 9.2 patch 2 was used to simulate the decay process of 170 Tm and to calculate the absorbed dose distribution using the GEANT4 Penelope physics models. A hypothetical 170 Tm source based on the Flexisource brachytherapy design with the active core set as a pure thulium cylinder (length 3.5 mm and diameter 0.6 mm) and different cylindrical source encapsulations (length 5 mm and thickness 0.125 mm) constructed of titanium, stainless-steel, gold, or platinum were simulated. The radial dose function for the line source approximation was calculated following the TG-43U1 formalism for the stainless-steel encapsulation. Results: For the titanium and stainless-steel encapsulation, 94% of the total bremsstrahlung is produced inside the core, 4.8 and 5.5% in titanium and stainless-steel capsules, respectively, and less than 1% in water. For the gold capsule, 85% is produced inside the core, 14.2% inside the gold capsule, and a negligible amount ( 170 Tm source is primarily a bremsstrahlung source, with the majority of bremsstrahlung photons being generated in the source core and experiencing little attenuation in the source encapsulation. Electrons are efficiently absorbed by the gold and platinum encapsulations. However, for the stainless-steel capsule (or other lower Z encapsulations) electrons will escape. The dose from these electrons is dominant over the photon dose in the first few millimeter but is not taken into account by current standard treatment planning systems. The total energy spectrum of photons emerging from the source depends on the encapsulation composition and results in mean photon energies well above 100 keV. This is higher than the main gamma-ray energy peak at 84 keV. Based on our

  6. 40 CFR 97.40 - Trading program budget.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Trading program budget. 97.40 Section...) FEDERAL NOX BUDGET TRADING PROGRAM AND CAIR NOX AND SO2 TRADING PROGRAMS NOX Allowance Allocations § 97.40 Trading program budget. In accordance with §§ 97.41 and 97.42, the Administrator will allocate to the NOX...

  7. Structural basis for the cooperative allosteric activation of the free fatty acid receptor GPR40

    Energy Technology Data Exchange (ETDEWEB)

    Lu, Jun; Byrne, Noel; Wang, John; Bricogne, Gerard; Brown, Frank K.; Chobanian, Harry R.; Colletti, Steven L.; Di Salvo, Jerry; Thomas-Fowlkes, Brande; Guo, Yan; Hall, Dawn L.; Hadix, Jennifer; Hastings, Nicholas B.; Hermes, Jeffrey D.; Ho, Thu; Howard, Andrew D.; Josien, Hubert; Kornienko, Maria; Lumb, Kevin J.; Miller, Michael W.; Patel, Sangita B.; Pio, Barbara; Plummer, Christopher W.; Sherborne, Bradley S.; Sheth, Payal; Souza, Sarah; Tummala, Srivanya; Vonrhein, Clemens; Webb, Maria; Allen, Samantha J.; Johnston, Jennifer M.; Weinglass, Adam B.; Sharma, Sujata; Soisson, Stephen M. (Merck); (Globel Phasing)

    2017-06-05

    Clinical studies indicate that partial agonists of the G-protein-coupled, free fatty acid receptor 1 GPR40 enhance glucose-dependent insulin secretion and represent a potential mechanism for the treatment of type 2 diabetes mellitus. Full allosteric agonists (AgoPAMs) of GPR40 bind to a site distinct from partial agonists and can provide additional efficacy. We report the 3.2-Å crystal structure of human GPR40 (hGPR40) in complex with both the partial agonist MK-8666 and an AgoPAM, which exposes a novel lipid-facing AgoPAM-binding pocket outside the transmembrane helical bundle. Comparison with an additional 2.2-Å structure of the hGPR40–MK-8666 binary complex reveals an induced-fit conformational coupling between the partial agonist and AgoPAM binding sites, involving rearrangements of the transmembrane helices 4 and 5 (TM4 and TM5) and transition of the intracellular loop 2 (ICL2) into a short helix. These conformational changes likely prime GPR40 to a more active-like state and explain the binding cooperativity between these ligands.

  8. Deformation in the neutron rich sulfur isotopes {sup 40}S and {sup 42}S

    Energy Technology Data Exchange (ETDEWEB)

    Glasmacher, T.; Scheit, H.; Brown, B.A. [Michigan State Univ., East Lansing, MI (United States)] [and others

    1996-12-31

    In the experiment described here radioactive beams of {sup 40,42}S and {sup 44,46}Ar (E{approx}40 MeV/nucl.) were produced in the A1200 fragment separator at the National Superconducting Cyclotron Laboratory at Michigan State University by fragmenting an 80 MeV/nucleon {sup 48}Ca{sup 13+} beam in a 379 mg/cm{sup 2} {sup 9}Be target. The exotic ions were positively identified by a time of flight measurement before interacting with the secondary gold target (93.5 mg/cm{sup 2} or 184.1 mg/cm{sup 2}). After interacting with the virtual photon field in the gold target, fragments scattered into a lab angle of less than 4.1{degrees} were detected in a fast/slow plastic phoswich detector located downstream from the secondary target. The energy loss - total energy measurement allowed the rejection of events which led to the breakup of the projectile in the target. Photons from the deexcitation of the projectile were measured in coincidence with beam particles. The photons emitted from the excited projectile can be clearly distinguished from photons coming from the target by their Doppler shift and Doppler broadening.

  9. Structural and functional importance of transmembrane domain 3 (TM3) in the aspartate:alanine antiporter AspT: topology and function of the residues of TM3 and oligomerization of AspT.

    Science.gov (United States)

    Nanatani, Kei; Maloney, Peter C; Abe, Keietsu

    2009-04-01

    AspT, the aspartate:alanine antiporter of Tetragenococcus halophilus, a membrane protein of 543 amino acids with 10 putative transmembrane (TM) helices, is the prototype of the aspartate:alanine exchanger (AAE) family of transporters. Because TM3 (isoleucine 64 to methionine 85) has many amino acid residues that are conserved among members of the AAE family and because TM3 contains two charged residues and four polar residues, it is thought to be located near (or to form part of) the substrate translocation pathway that includes the binding site for the substrates. To elucidate the role of TM3 in the transport process, we carried out cysteine-scanning mutagenesis. The substitutions of tyrosine 75 and serine 84 had the strongest inhibitory effects on transport (initial rates of l-aspartate transport were below 15% of the rate for cysteine-less AspT). Considerable but less-marked effects were observed upon the replacement of methionine 70, phenylalanine 71, glycine 74, arginine 76, serine 83, and methionine 85 (initial rates between 15% and 30% of the rate for cysteine-less AspT). Introduced cysteine residues at the cytoplasmic half of TM3 could be labeled with Oregon green maleimide (OGM), whereas cysteines close to the periplasmic half (residues 64 to 75) were not labeled. These results suggest that TM3 has a hydrophobic core on the periplasmic half and that hydrophilic residues on the cytoplasmic half of TM3 participate in the formation of an aqueous cavity in membranes. Furthermore, the presence of l-aspartate protected the cysteine introduced at glycine 62 against a reaction with OGM. In contrast, l-aspartate stimulated the reactivity of the cysteine introduced at proline 79 with OGM. These results demonstrate that TM3 undergoes l-aspartate-induced conformational alterations. In addition, nonreducing sodium dodecyl sulfate-polyacrylamide gel electrophoresis analyses and a glutaraldehyde cross-linking assay suggest that functional AspT forms homo-oligomers as a

  10. Structural and Functional Importance of Transmembrane Domain 3 (TM3) in the Aspartate:Alanine Antiporter AspT: Topology and Function of the Residues of TM3 and Oligomerization of AspT▿

    Science.gov (United States)

    Nanatani, Kei; Maloney, Peter C.; Abe, Keietsu

    2009-01-01

    AspT, the aspartate:alanine antiporter of Tetragenococcus halophilus, a membrane protein of 543 amino acids with 10 putative transmembrane (TM) helices, is the prototype of the aspartate:alanine exchanger (AAE) family of transporters. Because TM3 (isoleucine 64 to methionine 85) has many amino acid residues that are conserved among members of the AAE family and because TM3 contains two charged residues and four polar residues, it is thought to be located near (or to form part of) the substrate translocation pathway that includes the binding site for the substrates. To elucidate the role of TM3 in the transport process, we carried out cysteine-scanning mutagenesis. The substitutions of tyrosine 75 and serine 84 had the strongest inhibitory effects on transport (initial rates of l-aspartate transport were below 15% of the rate for cysteine-less AspT). Considerable but less-marked effects were observed upon the replacement of methionine 70, phenylalanine 71, glycine 74, arginine 76, serine 83, and methionine 85 (initial rates between 15% and 30% of the rate for cysteine-less AspT). Introduced cysteine residues at the cytoplasmic half of TM3 could be labeled with Oregon green maleimide (OGM), whereas cysteines close to the periplasmic half (residues 64 to 75) were not labeled. These results suggest that TM3 has a hydrophobic core on the periplasmic half and that hydrophilic residues on the cytoplasmic half of TM3 participate in the formation of an aqueous cavity in membranes. Furthermore, the presence of l-aspartate protected the cysteine introduced at glycine 62 against a reaction with OGM. In contrast, l-aspartate stimulated the reactivity of the cysteine introduced at proline 79 with OGM. These results demonstrate that TM3 undergoes l-aspartate-induced conformational alterations. In addition, nonreducing sodium dodecyl sulfate-polyacrylamide gel electrophoresis analyses and a glutaraldehyde cross-linking assay suggest that functional AspT forms homo-oligomers as a

  11. Brilliant blue, green and orange-red emission band on Tm{sup 3+}-, Tb{sup 3+}- and Eu{sup 3+}-doped ZrO{sub 2} nanocrystals

    Energy Technology Data Exchange (ETDEWEB)

    Romero, V H; De la Rosa, E; Lopez-Luke, T [Centro de Investigaciones en Optica, A.P. 1-948, Leon Gto., 37160 (Mexico); Salas, P [Centro de Fisica Aplicada y TecnologIa Avanzada, Universidad Nacional Autonoma de Mexico, A.P. 1-1010, Queretaro, Qro. 76000 (Mexico); Angeles-Chavez, C, E-mail: elder@cio.m [Instituto Mexicano del Petroleo, Programa de IngenierIa Molecular, A.P. 11-848, Mexico, D.F. 07730 (Mexico)

    2010-11-24

    Tm{sup 3+}-, Tb{sup 3+}- and Eu{sup 3+}-doped ZrO{sub 2} nanocrystals were prepared by a facile precipitation method with a hydrothermal process. Structural characterization showed a crystallite size ranging from 30 to 40 nm, and monoclinic and tetragonal zirconia phases were observed depending on the dopant concentration. The monoclinic phase was dominant for 0.5 mol% of Tb{sup 3+} and Eu{sup 3+}, and the tetragonal phase was 100% stabilized for 2 mol% of Tm{sup 3+} and Tb{sup 3+}. The structure of emission bands associated with Eu{sup 3+} confirms the substitution of Zr{sup 4+} located at C{sub 1} and D{sub 2h} symmetry sites for the monoclinic and tetragonal phases. The emission of three primary colours, red, green and blue, was obtained from Eu{sup 3+}, Tb{sup 3+} and Tm{sup 3+}, respectively, which makes this nanophosphor an excellent candidate for use in photonics applications. The emitted signal was analysed as a function of ion concentration and the optimum concentration was determined.

  12. Pool boiling performance of NovecTM 649 engineered fluid

    International Nuclear Information System (INIS)

    Forrest, Eric; Buongiorno, Jacopo; McKrell, Thomas; Hu, Lin-Wen

    2009-01-01

    A new fluorinated ketone, C 2 F 5 C(O)CF(CF 3 ) 2 , is currently being considered as an environmentally friendly alternative for power electronics cooling applications due to its high dielectric strength and low global warming potential (GWP). Sold commercially by the 3M Company as Novec TM 649 Engineered Fluid, C 2 F 5 C(O)CF(CF 3 ) 2 exhibits very low acute toxicity while maintaining long-term stability. To assess the general two-phase heat transfer performance of Novec TM 649, pool boiling tests were conducted by resistively heating a 0.01 in. diameter nickel wire at the fluid's atmospheric saturation temperature of 49 deg C. The nucleate boiling heat transfer coefficient and critical heat flux (CHF) obtained for the fluorinated ketone compare favorably with results obtained for FC-72, a fluorocarbon widely used for the direct cooling of electronic devices. Initial results indicate that Novec TM 649 may prove to be a viable alternative to FC-72 and other halo alkanes for the cooling of high power density electronic devices. (author)

  13. Use of the Aromascan(TM) Instrument for Nonsubjective Evaluation of Rodent Spaceflight Hardware

    Science.gov (United States)

    Scribner, K. A.; Steele, M. K.; Hinds, W. E.; Dalton, Bonnie P. (Technical Monitor)

    1997-01-01

    This report describes the verification and utilization of the AromaScan(TM) (Hollis, NH) instrument for the ground-based evaluation of odor containment by various spaceflight habitats developed at NASA's Ames Research Center (ARC). The AromaScan(TM) instrument is an electronic odor detection system consisting of 32 polymer sensors that respond differentially to 10 different chemical groups present in an air sample. The AromaScan(TM) system also includes neural network software for constructing a database of known odors, against which an unknown odor can be compared. At present, the standard method for characterizing rodent odor containment during the development and testing of spaceflight hardware is the use of a human odor assessment panel. However, this can be a very time consuming and costly process, and the results are inherently subjective. The AromaScan(TM) system should produce more consistent and objective results, as well as a cost savings in the long term. To test and verify the AromaScan(TM) instrument, daily air samples will be collected from the exhaust port of rodent habitats, during experiment development tests, then injected into the instrument and used to create a database of recognizable odors. Human sniff tests will be performed in conjunction with the AromaScan(TM) analysis, and the results will be correlated. We will then teach the neural network to differentiate between an acceptable and an unacceptable odor profile, as defined by the human sniff test, and to be able to accurately identify an odor that would not pass a sniff panel. The results of our efforts will be to verify that the AromaScan(TM) system is a valuable alternative to human sniff panel assessments for the early iterative process of designing and testing rodent waste filters for spaceflight. Acceptance by a human panel will remain one of the final criteria for successful rodent habitat development.

  14. Growth and optical properties of Tm:GdVO{sub 4} single crystal

    Energy Technology Data Exchange (ETDEWEB)

    Urata, Y.; Akagawa, K.; Wada, S.; Tashiro, H. [Photodynamics Research Center, Sendai (Japan). Inst. of Physical and Chemical Research; Suh, S.J.; Yoon, D.H. [Photodynamics Research Center, Sendai (Japan). Inst. of Physical and Chemical Research]|[Dept. of Metallurgical Engineering, Sung Kyun Kwan Univ. (Korea, Republic of); Fukuda, T. [Photodynamics Research Center, Sendai (Japan). Inst. of Physical and Chemical Research]|[Inst. for Materials Research, Tohoku Univ. (Japan)

    1999-04-01

    Thulium-doped gadolinium vanadate (Tm:GdVO{sub 4}) single crystal has been successfully grown by a modified Czochralski (CZ) technique. Effective distribution coefficient of Tm was determined to be 0.74. Absorption characterization was performed in the 800 nm region and the maximum absorption peak was found at 799 nm for {pi} polarization. Fluorescence spectra for tuning at the maximum absorption were obtained around 1.8-2.0 {mu}m region with 100 nm bandwidth. This suggests that a Tm:GdVO{sub 4} crystal is expected as a new promising LD pumped solid-state laser in the 2 {mu}m region. (orig.) 9 refs.

  15. LD-cladding-pumped 50 pm linewidth Tm 3+ -doped silica fiber laser.

    Science.gov (United States)

    Yunjun, Zhang; Baoquan, Yao; Youlun, Ju; Hui, Zhou; Yuezhu, Wang

    2008-05-26

    We report on a Tm(3+)-doped fiber laser source operating at 1936.4 nm with a very narrow linewidth (50 pm) laser output. Up to 2.4 W cw laser power was obtained from an 82 cm long Tm(3+)-doped multimode-core fiber cladding pumped by a 792 nm laser diode (LD). The fiber laser cavity included a high-reflective dichroic and a low-reflective FBG output coupler. The multimode fiber Bragg grating (FBG) transmission spectrum and output laser spectrum were measured. By adjusting the distance between the dichroic and the Tm(3+)-doped fiber end, the multipeak laser spectrum changed to a single-peak laser spectrum.

  16. Implementation of BIRADS{sup TM} together with an organization of percutaneous breast biopsies: experiences, reactions; Implementierung der BIRADS{sup TM}-Klassifikation in Kombination mit einer Organisation der perkutanen Nadelbiopsie von Brustlaesionen: Erfahrungen, Reaktionen

    Energy Technology Data Exchange (ETDEWEB)

    Hergan, K.; Oser, W. [Zentrales Inst. fuer Radiologie, LKH Feldkirch (Austria); Laengle, I. [Obmann der Fachgruppe Radiologie Vorarlberg (Austria)

    2002-12-01

    Purpose: To record the acceptance and reactions of radiologist und physicians who recommend patients for mammography after simultaneous establishment of BIRADS{sup TM} and a registration of the results of percutaneous breast biopsies. Materials and methods: To improve clarity of mammographic reports and to provide guidance concerning any necessary percutaneous breast biopsies the Breast Imaging Data And Reporting System (BIRADS{sup TM}) has been introduced regionally together with a registration of percutaneous breast biopsies. Using a questionnaire, 25 radiologists and 230 referring physicians were asked on acceptance and reactions concerning the established system. Results: Of the 15 answering radiologists, 93% considered BIRADS{sup TM} a worthwhile effort and 87% found the biopsy guidelines to be useful. They regarded the acceptance of the referring physicians and patients as high (80%). Up to 69% of the 52 participating physicians stated a better understanding of the mammographic reports, an easier comprehension of the dignity classification of a mammographic lesion and the feeling of an improvement in their work. Preoperative assessment of histology was found to be valuable by 94% of the referring physicians. They believe that more than half of the patients benefit from the biopsy guidelines and that the majority of patients accept this approach. Conclusion: BIRADS{sup TM} is useful to standardize and improve mammographic reports. It is advantageous to link BIRADS{sup TM} with guidelines for percutaneous breast biopsies. (orig.) [German] Ziel: Erfassung der Akzeptanz und Reaktionen von Radiologen und zur Mammographie zuweisenden Aerzten (Allgemeinmediziner, Gynaekologen) nach gleichzeitiger Einfuehrung von BIRADS{sup TM} und einer Organisation perkutaner Mammabiopsien. Material und Methode: Zur Synchronisation und besseren Verstaendlichkeit von mammographischen Befunden und zur Vorgabe klarer Richtlinien bez. der perkutanen Mammabiopsie wurde in einem regional

  17. PLUS 7TM advanced fuel assembly development program for KSNPs and APR1400

    International Nuclear Information System (INIS)

    Kim, Kyutae; Stucker, David L.

    2002-01-01

    KNFC and Westinghouse have recently completed the development of the PLUS 7 TM advanced 16 X 16 fuel assembly for the Korean Standard Nuclear Plants (KSNPs) and the Advanced Power Reactor 1400 (APR 1400). This fuel design utilized the proven advanced design features including mixing vane spacer grids to increase critical heat flux performance, ZIRLO TM advanced materials to enable high-duty, high burnup fuel management and an optimized fuel rod diameter which improves fuel cycle cost while resulting in significant standardization of Korean fuel manufacture. PLUS 7 TM , also includes a patented spacer grid design with conformal fuel rod support designed to provide superior fuel rod wear/fretting resistance while minimizing pressure drop. This paper will present an overview of the PLUS 7 TM fuel assembly development process including a summary of the three-year design and testing program from a mechanical, neutronic, and thermal/hydraulic perspective. The PLUS 7 TM fuel for the KSNPs and the APR1400 reactors results in multi-million dollar per cycle savings in imported enriched uranium product for the Korean nuclear power program with technology specifically developed for Korea by experienced Korean engineers

  18. Magnetic anomaly in superconducting TmRh4B4

    International Nuclear Information System (INIS)

    Smith, J.L.; Huang, C.Y.; Tsou, J.J.; Ho, J.C.

    1978-01-01

    The magnetic and superconducting properties of TmRh 4 B 4 (which becomes superconducting at 9.6 K) by means of ac and dc magnetic susceptibility and specific heat measurements are investigated. At 10.7 K, an ac susceptibility peak similar to those found in spin glasses has been observed. In addition, a pronounced specific heat peak has been observed at 11.4 K. The susceptibility peak is essentially unaffected by substitution of 1% Lu or Er for the Tm, but it diminishes when much larger amounts of Er are substituted. The physical origin of this anomalous peak will be discussed

  19. Microstructural Evolution, Thermodynamics, and Kinetics of Mo-Tm2O3 Powder Mixtures during Ball Milling

    Directory of Open Access Journals (Sweden)

    Yong Luo

    2016-10-01

    Full Text Available The microstructural evolution, thermodynamics, and kinetics of Mo (21 wt % Tm2O3 powder mixtures during ball milling were investigated using X-ray diffraction and transmission electron microscopy. Ball milling induced Tm2O3 to be decomposed and then dissolved into Mo crystal. After 96 h of ball milling, Tm2O3 was dissolved completely and the supersaturated nanocrystalline solid solution of Mo (Tm, O was obtained. The Mo lattice parameter increased with increasing ball-milling time, opposite for the Mo grain size. The size and lattice parameter of Mo grains was about 8 nm and 0.31564 nm after 96 h of ball milling, respectively. Ball milling induced the elements of Mo, Tm, and O to be distributed uniformly in the ball-milled particles. Based on the semi-experimental theory of Miedema, a thermodynamic model was developed to calculate the driving force of phase evolution. There was no chemical driving force to form a crystal solid solution of Tm atoms in Mo crystal or an amorphous phase because the Gibbs free energy for both processes was higher than zero. For Mo (21 wt % Tm2O3, it was mechanical work, not the negative heat of mixing, which provided the driving force to form a supersaturated nanocrystalline Mo (Tm, O solid solution.

  20. The Vitamin E Analog Gamma-Tocotrienol (GT3 and Statins Synergistically Up-Regulate Endothelial Thrombomodulin (TM

    Directory of Open Access Journals (Sweden)

    Rupak Pathak

    2016-11-01

    Full Text Available Statins; a class of routinely prescribed cholesterol-lowering drugs; inhibit 3-hydroxy-3-methylglutaryl-coenzymeA reductase (HMGCR and strongly induce endothelial thrombomodulin (TM; which is known to have anti-inflammatory; anti-coagulation; anti-oxidant; and radioprotective properties. However; high-dose toxicity limits the clinical use of statins. The vitamin E family member gamma-tocotrienol (GT3 also suppresses HMGCR activity and induces TM expression without causing significant adverse side effects; even at high concentrations. To investigate the synergistic effect of statins and GT3 on TM; a low dose of atorvastatin and GT3 was used to treat human primary endothelial cells. Protein-level TM expression was measured by flow cytometry. TM functional activity was determined by activated protein C (APC generation assay. Expression of Kruppel-like factor 2 (KLF2, one of the key transcription factors of TM, was measured by quantitative reverse transcription polymerase chain reaction (qRT-PCR. TM expression increased in a dose-dependent manner after both atorvastatin and GT3 treatment. A combined treatment of a low-dose of atorvastatin and GT3 synergistically up-regulated TM expression and functional activity. Finally; atorvastatin and GT3 synergistically increased KLF2 expression. These findings suggest that combined treatment of statins with GT3 may provide significant health benefits in treating a number of pathophysiological conditions; including inflammatory and cardiovascular diseases.

  1. Everything you need to know to operate on Day-Ahead{sup TM}; Tout ce que vous devez savoir pour intervenir sur Powernext Day-Ahead{sup TM}

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2005-05-15

    The introduction of a power exchange in France is a direct response to the opening up of the European electricity markets. Powernext SA is a Multilateral Trading Facility in charge of managing the French power exchange through an optional and anonymous organised exchange offering: - Day-ahead contracts for the management of volume risk on Powernext Day-Ahead{sup TM} since 21 November 2001, - Medium term contracts for the management of price risk on Powernext Futures{sup TM} since 18 June 2004. This document is the user's guide of Powernext Day-Ahead{sup TM}. It presents: 1 - the power exchange in France (market model, Powernext's regulatory environment, general market operations, 2 - Powernext Day-Ahead{sup TM} members (membership, agreement, start-up notification, tariffs, standing obligations, membership termination), 3 - Powernext Day-Ahead{sup TM} products (specifications, management), 4 - trading (connections, system flow chart, ElWeb client installation and daily connections, portfolio-management, single bidding, type of order, submitting, importing, saving, sending, modifying or canceling an order form, transmission problems, block bidding block bid characteristics, sending, saving, transmitting, modifying and canceling a block bid, price calculations, blind auction procedure, example, taking into account block bids, rounding off rules, consulting and saving the results, sample documents, auction validation), 5 - clearing (LCH.Clearnet SA, legal framework, clearing agreement, PP-DPES agreement, market security, initial margin, daily adjustments, additional margin calls, trade-related financial flows, net financial position, value-added tax, settlement statements, general idea, characteristics and transmission method of settlement statements sample Documents, cash calls, settlement, default, sample cash call documents, financial Reports), 6 - delivery (balance responsible entity, file characteristics and transmission, imbalance settlement

  2. Genetic characterization and improved genotyping of the dysferlin-deficient mouse strain Dysf (tm1Kcam).

    Science.gov (United States)

    Wiktorowicz, Tatiana; Kinter, Jochen; Kobuke, Kazuhiro; Campbell, Kevin P; Sinnreich, Michael

    2015-01-01

    Mouse models of dysferlinopathies are valuable tools with which to investigate the pathomechanisms underlying these diseases and to test novel therapeutic strategies. One such mouse model is the Dysf (tm1Kcam) strain, which was generated using a targeting vector to replace a 12-kb region of the dysferlin gene and which features a progressive muscular dystrophy. A prerequisite for successful animal studies using genetic mouse models is an accurate genotyping protocol. Unfortunately, the lack of robustness of currently available genotyping protocols for the Dysf (tm1Kcam) mouse has prevented efficient colony management. Initial attempts to improve the genotyping protocol based on the published genomic structure failed. These difficulties led us to analyze the targeted locus of the dysferlin gene of the Dysf (tm1Kcam) mouse in greater detail. In this study we resequenced and analyzed the targeted locus of the Dysf (tm1Kcam) mouse and developed a novel PCR protocol for genotyping. We found that instead of a deletion, the dysferlin locus in the Dysf (tm1Kcam) mouse carries a targeted insertion. This genetic characterization enabled us to establish a reliable method for genotyping of the Dysf (tm1Kcam) mouse, and thus has made efficient colony management possible. Our work will make the Dysf (tm1Kcam) mouse model more attractive for animal studies of dysferlinopathies.

  3. SynLam(TM) Primary Mirror Evaluation, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — Cornerstone Research Group, Inc. (CRG), has developed sandwich core composite material (SynLam(TM)) and related fabrication technology to address the drawbacks of...

  4. SYBR safeTM efficiently replaces ethidium bromide in Aspergillus fumigatus gene disruption.

    Science.gov (United States)

    Canela, H M S; Takami, L A; Ferreira, M E S

    2017-02-08

    Invasive aspergillosis is a disease responsible for high mortality rates, caused mainly by Aspergillus fumigatus. The available drugs are limited and this disease continues to occur at an unacceptable frequency. Gene disruption is essential in the search for new drug targets. An efficient protocol for A. fumigatus gene disruption was described but it requires ethidium bromide, a genotoxic agent, for DNA staining. Therefore, the present study tested SYBR safe TM , a non-genotoxic DNA stain, in A. fumigatus gene disruption protocol. The chosen gene was cipC, which has already been disrupted successfully in our laboratory. A deletion cassette was constructed in Saccharomyces cerevisiae and used in A. fumigatus transformation. There was no statistical difference between the tested DNA stains. The success rate of S. cerevisiae transformation was 63.3% for ethidium bromide and 70% for SYBR safe TM . For A. fumigatus gene disruption, the success rate for ethidium bromide was 100 and 97% for SYBR safe TM . In conclusion, SYBR safe TM efficiently replaced ethidium bromide, making this dye a safe and efficient alternative for DNA staining in A. fumigatus gene disruption.

  5. Powernext futuresTM front office user's guide

    International Nuclear Information System (INIS)

    2004-07-01

    The introduction of a power exchange in France is a direct response to the opening up of the European electricity markets. Powernext SA is a Multilateral Trading Facility in charge of managing the French power exchange through an optional and anonymous organised exchange offering: - Day-ahead contracts for the management of volume risk on Powernext Day-Ahead TM since 21 November 2001, - Medium term contracts for the management of price risk on Powernext Futures TM since 18 June 2004. This document is the front office user's guide, it presents: the market model (characteristics, regulation, contractual framework), the members (traders, clearers, quotation providers, fees structure), the products (specifications, use, liquidity and market efficiency), the trading system (architecture, hardware and software requirements, installation process and connecting to server), the trading (session, screen, sending an order, order execution). Contracts codifications and a glossary are given in the appendix. (J.S.)

  6. Chronic exposure to sublethal doses of radiation mimetic ZeocinTM selects for clones deficient in homologous recombination

    International Nuclear Information System (INIS)

    Delacote, Fabien; Deriano, Ludovic; Lambert, Sarah; Bertrand, Pascale; Saintigny, Yannick; Lopez, Bernard S.

    2007-01-01

    DNA double-strand breaks (DSBs) are highly toxic lesions leading to genome variability/instability. The balance between homologous recombination (HR) and non-homologous end-joining (NHEJ), two alternative DSB repair systems, is essential to ensure genome maintenance in mammalian cells. Here, we transfected CHO hamster cells with the pcDNA TM 3.1/Zeo plasmid, and selected transfectants with Zeocin TM , a bleomycin analog which produces DSBs. Despite the presence of a Zeocin TM resistance gene in pcDNA TM 3.1/Zeo, Zeocin TM induced 8-10 γ-H2AX foci per cell. This shows that the Zeocin TM resistance gene failed to fully detoxify cells treated with Zeocin TM , and that during selection cells were submitted to a chronic sublethal DSB stress. Selected clones show decreases in both spontaneous and induced intrachromosomal HR. In contrast, in an in vitro assay, these clones show an increase in NHEJ products specific to the KU86 pathway. We selected cells, in the absence of pcDNA TM 3.1/Zeo, with low and sublethal doses of Zeocin TM , producing a mean 8-10 γ-H2AX foci per cell. Newly selected clones exhibited similar phenotypes: HR decrease accompanied by an increase in KU86-dependent NHEJ efficiency. Thus chronic exposure to sublethal numbers of DSBs selects cells whose HR versus NHEJ balance is altered. This may well have implications for radio- and chemotherapy, and for management of environmental hazards

  7. Everything you need to know to operate on Day-AheadTM

    International Nuclear Information System (INIS)

    2005-05-01

    The introduction of a power exchange in France is a direct response to the opening up of the European electricity markets. Powernext SA is a Multilateral Trading Facility in charge of managing the French power exchange through an optional and anonymous organised exchange offering: - Day-ahead contracts for the management of volume risk on Powernext Day-Ahead TM since 21 November 2001, - Medium term contracts for the management of price risk on Powernext Futures TM since 18 June 2004. This document is the user's guide of Powernext Day-Ahead TM . It presents: 1 - the power exchange in France (market model, Powernext's regulatory environment, general market operations, 2 - Powernext Day-Ahead TM members (membership, agreement, start-up notification, tariffs, standing obligations, membership termination), 3 - Powernext Day-Ahead TM products (specifications, management), 4 - trading (connections, system flow chart, ElWeb client installation and daily connections, portfolio-management, single bidding, type of order, submitting, importing, saving, sending, modifying or canceling an order form, transmission problems, block bidding block bid characteristics, sending, saving, transmitting, modifying and canceling a block bid, price calculations, blind auction procedure, example, taking into account block bids, rounding off rules, consulting and saving the results, sample documents, auction validation), 5 - clearing (LCH.Clearnet SA, legal framework, clearing agreement, PP-DPES agreement, market security, initial margin, daily adjustments, additional margin calls, trade-related financial flows, net financial position, value-added tax, settlement statements, general idea, characteristics and transmission method of settlement statements sample Documents, cash calls, settlement, default, sample cash call documents, financial Reports), 6 - delivery (balance responsible entity, file characteristics and transmission, imbalance settlement, interconnection access), contacts and

  8. Detection of soil erosion within pinyon-juniper woodlands using Thematic Mapper (TM) data

    Science.gov (United States)

    Price, Kevin P.

    1993-01-01

    Multispectral measurements collected by Landsat Thematic Mapper (TM) were correlated with field measurements, direct soil loss estimates, and Universal Soil Loss Equation (USLE) estimates to determine the sensitivity of TM data to varying degrees of soil erosion in pinyon-juniper woodland in central Utah. TM data were also evaluated as a predictor of the USLE Crop Management C factor for pinyon-juniper woodlands. TM spectral data were consistently better predictors of soil erosion factors than any combination of field factors. TM data were more sensitive to vegetation variations than the USLE C factor. USLE estimates showed low annual rates of erosion which varied little among the study sites. Direct measurements of rate of soil loss using the SEDIMENT (Soil Erosion DIrect measureMENT) technique, indicated high and varying rates of soil loss among the sites since tree establishment. Erosion estimates from the USLE and SEDIMENT methods suggest that erosion rates have been severe in the past, but because significant amounts of soil have already been eroded, and the surface is now armored by rock debris, present erosion rates are lower. Indicators of accelerated erosion were still present on all sites, however, suggesting that the USLE underestimated erosion within the study area.

  9. Magnetic order and crystal fields in the Pnma phases of Tm2BaTO5(T=Co and Ni)

    International Nuclear Information System (INIS)

    Harker, S.J.; Stewart, G.A.

    2000-01-01

    The magnetic ordering and crystal field interactions of the Pnma phases of both Tm 2 BaCoO 5 and Tm 2 BaNiO 5 are investigated by 169 Tm Moessbauer spectroscopy and the temperature-dependent hyperfine interactions are compared with those obtained elsewhere for Tm 2 BaCuO 5 . The Pnma phases are shown to order magnetically at temperatures of 3.5(2) K (Tm 2 BaCoO 5 ) and 4.85(5) K (Tm 2 BaNiO 5 ), the order being induced by the transition metal. For Tm 2 BaNiO 5 an additional first-order transition observed at T≤1.4 K is identified with the independent magnetic order of the thulium sub-lattice. (orig.)

  10. Structural, photoluminescence and XPS properties of Tm3þ ions in ZnO nanostructures

    CSIR Research Space (South Africa)

    Kabongo, GL

    2017-07-01

    Full Text Available of photoluminescence (PL) spectroscopy. Finally, Tm 4d core level was detected in ZnO: 0.5 mol% Tm(sup3+) sample from high resolution X-Ray Photoelectron Spectroscopy (XPS) scan....

  11. Optical imaging of drillholes OL-KR40, OL-KR41, OL-KR41B, OL-KR42, OL-KR42B, OL-KR43 and OL-KR43B at Olkiluoto, 2006 and 2007

    International Nuclear Information System (INIS)

    Tarvainen, A.-M.

    2007-03-01

    Suomen Malmi Oy carried out optical imaging of drillholes OL-KR40, OL-KR41, OL-KR41B, OL-KR42, OL-KR42B, OL-KR43 and OL-KR43B at Olkiluoto site in Eurajoki during July, August, November and December 2006 as well as January 2007. The survey is a part of Posiva Oy's detailed investigation program for the final disposal of spent nuclear fuel. The assignment included the field work and the data processing. This report describes the field operation, the equipment as well as the processing procedures and shows the obtained results and their quality. The raw and processed data are delivered digitally in WellCAD and PDF format. (orig.)

  12. Diode-pumped mode-locked femtosecond Tm:CLNGG disordered crystal laser.

    Science.gov (United States)

    Ma, J; Xie, G Q; Gao, W L; Yuan, P; Qian, L J; Yu, H H; Zhang, H J; Wang, J Y

    2012-04-15

    A diode-end-pumped passively mode-locked femtosecond Tm-doped calcium lithium niobium gallium garnet (Tm:CLNGG) disordered crystal laser was demonstrated for the first time to our knowledge. With a 790 nm laser diode pumping, stable CW mode-locking operation was obtained by using a semiconductor saturable absorber mirror. The disordered crystal laser generated mode-locked pulses as short as 479 fs, with an average output power of 288 mW, and repetition rate of 99 MHz in 2 μm spectral region. © 2012 Optical Society of America

  13. Comparative study of diode-pumping self-injection and injection-locking Tm:YAG lasers

    International Nuclear Information System (INIS)

    Wu, C T; Chen, F; Ju, Y L; Wang, Y Z

    2013-01-01

    A comparative study of the laser characteristics of self-injection and injection-locking Tm:YAG lasers is given in this paper. At a pump energy of 145 mJ and Q-switched repetition rate of 100 Hz, an output energy of 2.39 mJ was obtained for an injection-locking Tm:YAG laser, with a pulse width of 403.2 ns and a pulse building-up time of 2.12 μs. Under the same conditions, the output energy, pulse width and pulse build-up time for a self-injection Tm:YAG laser were 2.21 mJ, 407.0 ns and 3.95 μs, respectively. The threshold of the Q-switched injection-locking Tm:YAG laser was much lower than that of the self-injection laser, and the pulse width was narrower and the pulse build-up time shorter. Additionally, the output spectrum was much purer for the injection-locking laser. (paper)

  14. Optical transitions of Tm3+ in oxyfluoride glasses and compositional and thermal effect on upconversion luminescence of Tm3+/Yb3+-codoped oxyfluoride glasses.

    Science.gov (United States)

    Feng, Li; Wu, Yinsu; Liu, Zhuo; Guo, Tao

    2014-01-24

    Optical properties of Tm(3+)-doped SiO2-BaF2-ZnF2 glasses have been investigated on the basis of the Judd-Ofelt theory. Judd-Ofelt intensity parameters, radiative transition probabilities, fluorescence branching ratios and radiative lifetimes have been calculated for different glass compositions. Upconversion emissions were observed in Tm(3+)/Yb(3+)-codoped SiO2-BaF2-ZnF2 glasses under 980 nm excitation. The effects of composition, concentration of the doping ions, temperature, and excitation pump power on the upconversion emissions were also systematically studied. Copyright © 2013 Elsevier B.V. All rights reserved.

  15. Simple countermeasures against the TM110-beam-blowup-mode in biperiodic structures

    International Nuclear Information System (INIS)

    Euteneuer, H.; Herminghaus, H.; Schoeler, H.

    1984-01-01

    The two fundamental methods of fighting beam blow-up in rf-accelerating-structures are staggered detuning and selective Q-spoiling of their higher order modes. Biperiodic structures offer a very simple way of applying the latter technique of the most dangerous TM 110 -like blowup mode at 1.7 times the accelerating frequency: letting this mode propagate but giving a large gap to the TM 110 -passband. This gap must be positive for electric coupling (f(phi=0) =1.7c. With asymmetric coupling elements between the cavities of a structure, one has a simple tool for staggered detuning: a change of the relative orientation of these elements spreads the resonance frequencies not only of the TM 110 -mode, but of at least all dipole modes. (orig.)

  16. The SmpB C-terminal tail helps tmRNA to recognize and enter stalled ribosomes

    Directory of Open Access Journals (Sweden)

    Mickey R. Miller

    2014-09-01

    Full Text Available In bacteria, transfer-messenger RNA (tmRNA and SmpB comprise the most common and effective system for rescuing stalled ribosomes. Ribosomes stall on mRNA transcripts lacking stop codons and are rescued as the defective mRNA is swapped for the tmRNA template in a process known as trans-translation. The tmRNA–SmpB complex is recruited to the ribosome independent of a codon–anticodon interaction. Given that the ribosome uses robust discriminatory mechanisms to select against non-cognate tRNAs during canonical decoding, it has been hard to explain how this can happen. Recent structural and biochemical studies show that SmpB licenses tmRNA entry through its interactions with the decoding center and mRNA channel. In particular, the C-terminal tail of SmpB promotes both EFTu activation and accommodation of tmRNA, the former through interactions with 16S rRNA nucleotide G530 and the latter through interactions with the mRNA channel downstream of the A site. Here we present a detailed model of the earliest steps in trans-translation, and in light of these mechanistic considerations, revisit the question of how tmRNA preferentially reacts with stalled, non-translating ribosomes.

  17. On the energy confinement in the TM-G tokamak with high plasma density

    International Nuclear Information System (INIS)

    Stefanovskij, A.M.

    1986-01-01

    Energy confinement time τ E , when plasma density changing, has been measured at the TM-G-tokamak device with a graphite discharge chamber. The measurements have been carried out in three different discharge modes with a similar stability margin on the limiter (q L )=3) and with different values of the discharge current of a longitudinal field (I p =20, 40 and 60 kA, V T =0.8; 1.6 and 2.4 T). On the basis of experimental data analysis the conclusion is made that saturation of τ E (n e ) dependence at high plasma density occurs due to current channel compression and violation of a ''self-consistent'' profile of current density. Drift wave excitation at densities similar to the limiting Murakami density can also play an important role

  18. Luminescence properties of Tm3+ ions single-doped YF3 materials in an unconventional excitation region.

    Science.gov (United States)

    Chen, Yuan; Liu, Qing; Lin, Han; Yan, Xiaohong

    2018-05-01

    According to the spectral distribution of solar radiation at the earth's surface, under the excitation region of 1150 to 1350 nm, the up-conversion luminescence of Tm 3+ ions was investigated. The emission bands were matched well with the spectral response region of silicon solar cells, achieved by Tm 3+ ions single-doped yttrium fluoride (YF 3 ) phosphor, which was different from the conventional Tm 3+ /Yb 3+ ion couple co-doped materials. Additionally, the similar emission bands of Tm 3+ ions were achieved under excitation in the ultraviolet region. It is expected that via up-conversion and down-conversion routes, Tm 3+ -sensitized materials could convert photons to the desired wavelengths in order to reduce the energy loss of silicon solar cells, thereby enhancing the photovoltaic efficiency. Copyright © 2018 John Wiley & Sons, Ltd.

  19. 77 FR 69548 - Price for the 2012 Limited Edition Silver Proof SetTM

    Science.gov (United States)

    2012-11-19

    ... DEPARTMENT OF THE TREASURY United States Mint Price for the 2012 Limited Edition Silver Proof Set TM AGENCY: United States Mint, Department of the Treasury. ACTION: Notice. SUMMARY: The United States Mint is announcing a price of $149.95 for the 2012 Limited Edition Silver Proof Set TM . FOR FURTHER...

  20. A tm Plug-In for Distributed Text Mining in R

    Directory of Open Access Journals (Sweden)

    Stefan Theussl

    2012-11-01

    Full Text Available R has gained explicit text mining support with the tm package enabling statisticians to answer many interesting research questions via statistical analysis or modeling of (text corpora. However, we typically face two challenges when analyzing large corpora: (1 the amount of data to be processed in a single machine is usually limited by the available main memory (i.e., RAM, and (2 the more data to be analyzed the higher the need for efficient procedures for calculating valuable results. Fortunately, adequate programming models like MapReduce facilitate parallelization of text mining tasks and allow for processing data sets beyond what would fit into memory by using a distributed file system possibly spanning over several machines, e.g., in a cluster of workstations. In this paper we present a plug-in package to tm called tm.plugin.dc implementing a distributed corpus class which can take advantage of the Hadoop MapReduce library for large scale text mining tasks. We show on the basis of an application in culturomics that we can efficiently handle data sets of significant size.

  1. Luminescence properties of Yb:Nd:Tm:KY{sub 3}F{sub 10} nanophosphor and thermal treatment effects

    Energy Technology Data Exchange (ETDEWEB)

    Gomes, Laércio, E-mail: lgomes@ipen.br [Centro de Lasers e Aplicações, Instituto de Pesquisas Energéticas e Nucleares, IPEN-CNEN/SP, Butantã, P.O. Box 11049, São Paulo, SP o5422-970 (Brazil); Linhares, Horácio Marconi da Silva M.D. [Centro de Lasers e Aplicações, Instituto de Pesquisas Energéticas e Nucleares, IPEN-CNEN/SP, Butantã, P.O. Box 11049, São Paulo, SP o5422-970 (Brazil); Ichikawa, Rodrigo Uchida; Martinez, Luis Gallego [Departamento de Ciências dos Materiais, Instituto de Pesquisas Energéticas e Nucleares (Brazil); Ranieri, Izilda Marcia [Centro de Lasers e Aplicações, Instituto de Pesquisas Energéticas e Nucleares, IPEN-CNEN/SP, Butantã, P.O. Box 11049, São Paulo, SP o5422-970 (Brazil)

    2015-01-15

    In this work, we present the spectroscopic properties of KY{sub 3}F{sub 10} (KY3F) nanocrystals activated with thulium and codoped with ytterbium and neodymium ions. The most important processes that lead to the thulium upconversion emissions in the blue region were identified. A time-resolved luminescence spectroscopy technique was employed to measure the luminescence decays and to determine the most important mechanisms involved in the upconversion process that populates {sup 1}G{sub 4} (Tm{sup 3+}) excited states. Analysis of the energy-transfer processes dynamics using selective pulsed-laser excitations in Yb:Nd:Tm, Nd:KY3F nanocrystals shows that the direct energy transfer from Nd{sup 3+} to Tm{sup 3+} ions is the mechanism responsible for the 78% of the blue upconversion luminescence in the Yb:Nd:Tm:KY3F when compared with the Yb:Nd:Tm:KY3F bulk crystal for an laser excitation at 802 nm. An investigation of the {sup 1}G{sub 4} level luminescence kinetic of Tm{sup 3+} in Yb/Nd/Tm system revealed that the luminescence efficiency ({sup 1}G{sub 4}) starts with a very low value (0.38%) for the synthesized nanocrystal (as grown) and strongly increases to 97% after thermal treatment at 550 °C for 6 h under argon flow. As a consequence of the thermal treatment at T=550 °C, the contributions of the (Nd×Tm) (Up{sub 1}) and (Nd×Yb×Tm) (Up{sub 2}) upconversion processes to the {sup 1}G{sub 4} luminescence are 33% (Up{sub 1}) and 67% for Up{sub 2}. Up{sub 2} process represented by Nd{sup 3+} ({sup 4}F{sub 3/2})→Yb{sup 3+} ({sup 2}F{sub 7/2}) followed by Yb{sup 3+} ({sup 2}F{sub 5/2})→Tm ({sup 3}H{sub 4})→Tm{sup 3+} ({sup 1}G{sub 4}) was previously reported as the main mechanism to produce the blue luminescence in Yb:Nd:Tm:YLiF{sub 4} and KY{sub 3}F{sub 10} bulk crystals. Results of X-ray diffraction analysis of nanopowder using the Rietveld method reveled that crystallite sizes remain unchanged (12–14 nm) after thermal treatments with T≤400 °C, while the

  2. FLOQSwabTM: optimisation of procedures for the recovery of microbiological samples from surfaces

    Directory of Open Access Journals (Sweden)

    Guido Finazzi

    2016-08-01

    Full Text Available The FLOQSwabTM is a specimen collection device worldwide recognised for its superior performance in the clinical diagnostics. The aim of this work was to evaluate FLOQSwabTM for the recovery of microbiological samples from surfaces compared to the traditional swab (rayon tipped swab as per ISO 18593:2004 standard. The FLOQSwabTM, thanks to its innovative manufacturing technology, allows improving the efficiency of recovery and release of analyte. The study has been divided into two experiments. In the first experiment the two swabs were evaluated for their capacity to recover and release the analyte (three different bacterial loads of Escherichia coli. In the second experiment, the two swabs were evaluated for their capacity to recover three different bacterial loads of E. coli from two different surface materials (stainless steel and polypropylene. In all experiments the flocked swab demonstrated a higher recovery rate compared to the traditional rayon tipped swab. The data obtained from this preliminary study demonstrated that the FLOQSwabTM could be a good food surfaces collection device, which improves the recovery of the analyte and thus produces accurate results. Based on the outcomes of the study, a larger field study is in progress using the FLOQSwabTM for samples collection to improve both environmental monitoring and the efficacy of the hygiene controls for food safety.

  3. Theoretical investigation of electronic, magnetic and optical properties of ZnSe doped TM and co-doped with MnTM (TM: Fe, Cr, Co): AB-initio study

    Energy Technology Data Exchange (ETDEWEB)

    Behloul, M. [LMPHE (URAC 12), Departement of Physique, B.P. 1014, Faculty of Science, University Mohammed V, Rabat (Morocco); Salmani, E., E-mail: elmehdisalmani@gmail.com [LMPHE (URAC 12), Departement of Physique, B.P. 1014, Faculty of Science, University Mohammed V, Rabat (Morocco); Ez-Zahraouy, H. [LMPHE (URAC 12), Departement of Physique, B.P. 1014, Faculty of Science, University Mohammed V, Rabat (Morocco); Benyoussef, A. [LMPHE (URAC 12), Departement of Physique, B.P. 1014, Faculty of Science, University Mohammed V, Rabat (Morocco); The Institute for Nanomaterials and Nanotechnology, MAScIR (Moroccan Fondation for Advanced Science, Innovation and Research), Rabat (Morocco)

    2016-12-01

    Based upon the first principal spin density functional calculation, the electronic, magnetic and optical properties of ZnTMSe and ZnMnTMSe where TM=Fe, Cr, Co are studied using the Korringa-Kohn-Rostoker coherent potential approximation (KKR-CPA) method within the local density (LDA)and the self-interaction-corrected(SIC) approximation. The purpose of this study is to determine the effect of different type of dopant and concentration on ferromagnetic and half metallic behavior of ZnSe. Therefore the magnetic disorder local moment (DLM) and the ferromagnetic state are investigated for different concentrations of Mn, Fe, Cr and Co; also the advantages of co-doped ZnSe with TM elements, behavior at room temperature are discussed. The electronic structure and optical properties are studied employing the local density (LDA) and the self-interaction-corrected (SIC) approximation. Moreover, the X-ray spectra modeling are in good agreement with the electronic and magnetic properties results. - Highlights: • The magnetic properties of ZnSe codoped with MnY(Y: Fe, Cr, Co) has been investigated. • The half-metallic appears in ZnSe codoped with impurities at low concentration. • The advantages of codoped ZnSe with impurities at room temperature are discussed.

  4. 76 FR 15047 - Pricing for 2010 United States Mint America the Beautiful Quarters Silver Proof SetTM

    Science.gov (United States)

    2011-03-18

    ... DEPARTMENT OF THE TREASURY United States Mint Pricing for 2010 United States Mint America the Beautiful Quarters Silver Proof Set\\TM\\, etc. ACTION: Pricing for 2010 United States Mint America the Beautiful Quarters Silver Proof Set TM ; 2010 United States Mint Silver Proof Set TM ; 2011 United States...

  5. Electrochemical study of Tm (III) ions on W and oxo acidity reactions in the LiCI-KCI eutectic; Estudio electroquimico de disoluciones de Tm (III) sobre W y reacciones de oxoacidez en el eutectico LiCI.-KCl

    Energy Technology Data Exchange (ETDEWEB)

    Fernandez Requejo, P.

    2010-07-01

    Study of the electrochemical behaviour of Tm (III) dissolutions in the LiCI-KCI eutectic mixture using inert electrodes (W) and reagent electrodes (Al). On W, TM (III) ions are reduced in two consecutives stages sufficiently separated. The TM electro-reduction on Al makes room for the formation of intermetallic compounds so the use of an Ai electrode is appropriate to decontamination operations.

  6. tmBioC: improving interoperability of text-mining tools with BioC.

    Science.gov (United States)

    Khare, Ritu; Wei, Chih-Hsuan; Mao, Yuqing; Leaman, Robert; Lu, Zhiyong

    2014-01-01

    The lack of interoperability among biomedical text-mining tools is a major bottleneck in creating more complex applications. Despite the availability of numerous methods and techniques for various text-mining tasks, combining different tools requires substantial efforts and time owing to heterogeneity and variety in data formats. In response, BioC is a recent proposal that offers a minimalistic approach to tool interoperability by stipulating minimal changes to existing tools and applications. BioC is a family of XML formats that define how to present text documents and annotations, and also provides easy-to-use functions to read/write documents in the BioC format. In this study, we introduce our text-mining toolkit, which is designed to perform several challenging and significant tasks in the biomedical domain, and repackage the toolkit into BioC to enhance its interoperability. Our toolkit consists of six state-of-the-art tools for named-entity recognition, normalization and annotation (PubTator) of genes (GenNorm), diseases (DNorm), mutations (tmVar), species (SR4GN) and chemicals (tmChem). Although developed within the same group, each tool is designed to process input articles and output annotations in a different format. We modify these tools and enable them to read/write data in the proposed BioC format. We find that, using the BioC family of formats and functions, only minimal changes were required to build the newer versions of the tools. The resulting BioC wrapped toolkit, which we have named tmBioC, consists of our tools in BioC, an annotated full-text corpus in BioC, and a format detection and conversion tool. Furthermore, through participation in the 2013 BioCreative IV Interoperability Track, we empirically demonstrate that the tools in tmBioC can be more efficiently integrated with each other as well as with external tools: Our experimental results show that using BioC reduces >60% in lines of code for text-mining tool integration. The tmBioC toolkit

  7. High-efficiency 2 μm Tm-doped fiber laser

    International Nuclear Information System (INIS)

    Dvornikov, D.

    2013-01-01

    Full text: Tm doped fiber laser operating in so called 'eye safe' wavelength region and designed in a MOPA configuration has been demonstrated. Large-mode-area fiber design and availability of high-brightness, high-power pump diodes at 795 nm made possible maximum output power of 25 W achieved at incident pump power of 72 W resulting in optical conversion efficiency about 35%. An important factor that led to an interest in 2 μm Tm-doped lasers is significantly broader spectral tunability of Tm-doped fibers compared to Yb-doped fibers, spanning wavelengths from below 1850 nm to beyond 2100 nm, corresponding to more than 200 nm of available bandwidth. This wavelength region covers the water absorption peaks around 1940 nm, making these lasers a valuable tool for precise medical procedures including noninvasive surgery, as well as several atmospheric transmission windows that are useful for remote sensing, laser radar and range-finding. This work was carried out as part of the EU funded Joint Operational Programme 'Black Sea Basin 2007-2013' and project 2.2.1.74459.339, MIS-ETC 1443 'Research networking for the environmental monitoring and mitigation of adverse ecological effects in the Black Sea Basin (BSB Net-Eco)'.

  8. Atypical PKC, PKCλ/ι, activates β-secretase and increases Aβ1-40/42 and phospho-tau in mouse brain and isolated neuronal cells, and may link hyperinsulinemia and other aPKC activators to development of pathological and memory abnormalities in Alzheimer's disease.

    Science.gov (United States)

    Sajan, Mini P; Hansen, Barbara C; Higgs, Margaret G; Kahn, C Ron; Braun, Ursula; Leitges, Michael; Park, Collin R; Diamond, David M; Farese, Robert V

    2018-01-01

    Hyperinsulinemia activates brain Akt and PKC-λ/ι and increases Aβ 1-40/42 and phospho-tau in insulin-resistant animals. Here, we examined underlying mechanisms in mice, neuronal cells, and mouse hippocampal slices. Like Aβ 1-40/42 , β-secretase activity was increased in insulin-resistant mice and monkeys. In insulin-resistant mice, inhibition of hepatic PKC-λ/ι sufficient to correct hepatic abnormalities and hyperinsulinemia simultaneously reversed increases in Akt, atypical protein kinase C (aPKC), β-secretase, and Aβ 1-40/42 , and restored acute Akt activation. However, 2 aPKC inhibitors additionally blocked insulin's ability to activate brain PKC-λ/ι and thereby increase β-secretase and Aβ 1-40/42 . Furthermore, direct blockade of brain aPKC simultaneously corrected an impairment in novel object recognition in high-fat-fed insulin-resistant mice. In neuronal cells and/or mouse hippocampal slices, PKC-ι/λ activation by insulin, metformin, or expression of constitutive PKC-ι provoked increases in β-secretase, Aβ 1-40/42 , and phospho-thr-231-tau that were blocked by various PKC-λ/ι inhibitors, but not by an Akt inhibitor. PKC-λ/ι provokes increases in brain β-secretase, Aβ 1-40/42 , and phospho-thr-231-tau. Excessive signaling via PKC-λ/ι may link hyperinsulinemia and other PKC-λ/ι activators to pathological and functional abnormalities in Alzheimer's disease. Published by Elsevier Inc.

  9. Use of Readycult[tm] - LMX for enumeration of total coliforms and Escherichia coli in milk

    Directory of Open Access Journals (Sweden)

    Beloti Vanerli

    2002-01-01

    Full Text Available Readycult[tm] - LMX is a rapid method to test for the presence of total coliform bacteria and Escherichia coli in water, giving results in 24h. It is based on reactions of specific microbial enzymes or indicator nutrients of the medium. The goal of this paper was to study the use of Readycult[tm] - LMX to detect total coliform and E. coli in milk. One hundred twenty five samples of pasteurized and raw milk, collected in Londrina, PR, Brazil, were tested simultaneously by the most probable number (MPN method using Brilliant Green Bile Lactose Broth (2% (BRILA and Readycult[tm] - LMX. The Readycult[tm] - LMX test was evaluated for sensitivity, simplicity, and speed of results. There was a significant correlation between the results obtained by the two methods for total coliforms (r: 0.8224 and for E. coli (r: 0.8603. The two methods yielded similar results, but Readycult[tm] - LMX was easier to use. In addition, results were available as early as 24h.

  10. Afterglow properties of CaF2:Tm nanoparticles and its potential application in photodynamic therapy

    International Nuclear Information System (INIS)

    Zahedifar, M.; Sadeghi, E.; Shanei, M.M.; Sazgarnia, A.; Mehrabi, M.

    2016-01-01

    CaF 2 :Tm nanoparticles (NPs) were synthesized by the hydrothermal method. Intense afterglow emission with long life time was found for the produced NPs, so its applicability in photodynamic therapy was investigated. Since the wavelength of the afterglow emission of the NPs fairly matches with the absorption band of the PpIX sensitizer, especially in the red region, the Cystein mediator was used to bond NPs with the PpIX sensitizer. The CaF 2 :Tm NPs conjugated with PpIX was exposed to X-ray and by using the Antracene as detector, the production of the singlet oxygen was verified. Therefore, the produced NPs are recommended as a source of energy that improves photodynamic therapy beyond its current limitations. - Highlights: • Intense afterglow emission found for the synthesized CaF 2 :Tm nanoparticles. • CaF 2 :Tm emission band fairly matched with PpIX sensitizer's absorption band. • CaF 2 :Tm conjugated with the sensitized is a good candidate for photodynamic therapy. • The application of nanoparticles in producing singlet oxygen was verified.

  11. Terahertz Magnon-Polaritons in TmFeO3.

    Science.gov (United States)

    Grishunin, Kirill; Huisman, Thomas; Li, Guanqiao; Mishina, Elena; Rasing, Theo; Kimel, Alexey V; Zhang, Kailing; Jin, Zuanming; Cao, Shixun; Ren, Wei; Ma, Guo-Hong; Mikhaylovskiy, Rostislav V

    2018-04-18

    Magnon-polaritons are shown to play a dominant role in the propagation of terahertz (THz) waves through TmFeO 3 orthoferrite, if the frequencies of the waves are in the vicinity of the quasi-antiferromagnetic spin resonance mode. Both time-domain THz transmission and emission spectroscopies reveal clear beatings between two modes with frequencies slightly above and slightly below this resonance, respectively. Rigorous modeling of the interaction between the spins of TmFeO 3 and the THz light shows that the frequencies correspond to the upper and lower magnon-polariton branches. Our findings reveal the previously ignored importance of propagation effects and polaritons in such heavily debated areas as THz magnonics and THz spectroscopy of electromagnons. It also shows that future progress in these areas calls for an interdisciplinary approach at the interface between magnetism and photonics.

  12. Intercalibration of analytical methods on marine environmental samples. Results of MEDPOL II exercise for the intercomparison of trace element measurements on mussel tissue homogenate and marine sediment (MA-M-2/TM and SD-N-1/2/TM)

    International Nuclear Information System (INIS)

    1986-12-01

    Mussels and coastal sediments are often considered as pollution indicators of the marine environment. These intercalibration exercises were organised in order to check the analytical performances of environmental laboratories. The samples MA-M-2/TM of Mediterranean mussels and SD-N-1/2/TM of surface sediment from the Scheldt Estuary (North Sea) were analysed by 19 laboratories for determination of 15 elements: Ag, As, Cd, Co, Cr, Cu, Fe, Hg, Mn, Ni, Pb, Sb, Se, V and Zn. The analytical methods of atomic absorption spectroscopy, neutron activation analysis and voltametry were used in this intercomparison. For the mussel MA-M-2/TM, 65% of the reported coefficients of variation lie between 0 and 10%, 25% are between 10 and 20%, 9% between 20 and 30% and only 1% higher than 30%. In the case of the sediment SD-N-1/2/TM, 90% of the reported coefficients of variation lie between 0 and 10% and the remaining 10% are between 10 and 20%. The total number of outliers is moderate (9.2% of all results in the case of MA-M-2/TM and 3.0% in the case of SD-N-1/2/TM)

  13. Nanocrystals of a new complex perovskite dielectric Ba{sub 2}TmSbO{sub 6}

    Energy Technology Data Exchange (ETDEWEB)

    Nair, V.M. [Department of Physics, University College, Trivandrum 695034, Kerala (India); Jose, R., E-mail: rjose@ump.edu.my [Faculty of Industrial Sciences and Technology, Universiti Malaysia Pahang, 26300 Kuantan (Malaysia); Anil Kumar, G.M. [Noritake Co Ltd, 300 Higashiyama, Miyoshi, Aichi 470-0293 (Japan); Yusoff, Mashitah M. [Faculty of Industrial Sciences and Technology, Universiti Malaysia Pahang, 26300 Kuantan (Malaysia); Wariar, P.R.S. [Department of Physics, University College, Trivandrum 695034, Kerala (India)

    2012-01-25

    Highlights: Black-Right-Pointing-Pointer A new material, Ba{sub 2}TmSbO{sub 6}, has been synthesized as nanocrystals for the first time. Black-Right-Pointing-Pointer A combustion process, characterized by a one-pot procedure, was adopted to synthesize Ba{sub 2}TmSbO{sub 6} as nanocrystals. Black-Right-Pointing-Pointer Crystal structure and dielectric properties of the Ba{sub 2}TmSbO{sub 6} have been studied and compared with similar materials. - Abstract: Nanocrystals of a new complex perovskites ceramic oxide, barium thulium antimony oxide - Ba{sub 2}TmSbO{sub 6}, were synthesized using a single step auto-ignition combustion process. The combustion product was single phase and composed of aggregates of nanocrystals of sizes in the range 20-50 nm. Ba{sub 2}TmSbO{sub 6} crystallized in cubic perovskite structure with lattice parameter, a = 8.4101 Angstrom-Sign . The polycrystalline fluffy combustion product was sintered to high density ({approx}97%) at {approx}1450 Degree-Sign C for 4 h. Resistivity of the sintered specimen was {approx}5 M{Omega}/cm. The Ba{sub 2}TmSbO{sub 6} has dielectric constant ({epsilon} Prime ) and dielectric loss (tan {delta}) of 17 and {approx}10{sup -4} at 5 MHz; the new material would probably be developed as a low-loss dielectric material.

  14. Thermal-hydraulic effects of transition to improved System 80TM fuel

    International Nuclear Information System (INIS)

    Rodack, T.; Joffre, P.F.; Kapoor, R.K.

    2004-01-01

    ABB CE's improved System 80 TM PWR fuel design includes GUARDIAN debris-resistant features and laser-welded Zircaloy grids. The GUARDIAN features include an Inconel grid with debris-filtering features located just above the Lower End Fitting, and a solid fuel rod bottom end cap that extends above the filtering features. Tests and analyses were done to establish the impact of these design improvements on fuel assembly hydraulic performance. Further analysis was done to determine the mixed core thermal-hydraulic performance as the transition is made over two fuel cycles to a full core of the improved System 80 TM fuel. Results confirm that the Thermal-Hydraulic (T-H) effects of the reduction in hydraulic resistance between the improved and resident fuel due to the laser-welded Zircaloy grids offsets the effects of the increased resistance GUARDIAN grid. Therefore, the mechanically improved System 80 TM fuel can be implemented with no net impact on Departure from Nucleate Boiling (DNB) margin in transition cores. (author)

  15. Computer Aided Analysis of TM-Multimode Planar Graded-index Optical Waveguides

    International Nuclear Information System (INIS)

    Ashry, M.; Nasr, A.S.; Abou El-Fadl, A.A.

    2000-01-01

    An algorithm is developed for analysis TM-Multimode Planar graded-index optical waveguides. A Modified Impedance Boundary Method of Moments (MIBMOM) for the analysis of planar graded-index optical waveguide structures is presented. The algorithm is used to calculate the dispersion characteristics and the field distribution of TM-multimode planar graded-index optical waveguides. The technique is based on Galerkin s procedure and the exact boundary condition at the interfaces between the graded index region and the step index cladding. Legendre polynomials are used as basis functions. The efficiency of this algorithm is examined with waveguides having various index profiles such as exponential, Gaussian and complementary error functions. The advantage of the MIBMOM is the complete solution of TM-multimode as presented which is very difficult by the other methods. With this algorithm a minimum number of basis functions to give accurate results is used. The obtained results show good agreement with the experimental results

  16. Development of movie caption translation lecture site using MobileMotion{sub TM}; MobileMotion{sub TM} wo mochiita jimaku hon'yaku koza site no kaihatsu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    The site of Internet that performs the correspondence education for bringing up a movie caption translator was developed. Correspondence education that fully deepens understanding was obtained by distributing a motion picture using MPEG-4 distribution software (MobileMotion{sub TM}) and performing the learning based on bi-directional communication. HTML distribution and E-mail transmission and reception are done from Gaga Communications, and a MobileMotion{sub TM} file is distributed from the OnDemand Server of Toshiba. This reduces the communication traffic of heavy motion picture data. (translated by NEDO)

  17. Emission characteristics of the Yb3+-sensitized Tm3+-doped optical fiber upon pumping with infrared LED

    International Nuclear Information System (INIS)

    Htein, Lin; Fan, Weiwei; Han, Won-Taek

    2014-01-01

    Near infrared emissions at 975, 1040 and 1450 nm of the Yb 3+ -sensitized Tm 3+ -doped optical fiber were obtained upon simultaneous excitation of Yb 3+ and Tm 3+ ions using the infrared LED. -- Highlights: • A novel pumping scheme for 1450 nm emission from 3 H 4 → 3 F 4 transition of Tm was demonstrated. • The absorption bands of Yb and Tm located within 690–970 nm were simultaneously excited with the IR LED. • Near infrared emissions at 975, 1040 and 1450 nm were obtained. • The Yb 3+ /Tm 3+ -codoped fiber showed the good spectroscopic quality and the increase of radiative lifetime of 3 H 4 level. • This LED pumping scheme can be useful for low-cost S-band fiber laser/amplifier applications

  18. Spaceflight 2 um Tm Fiber MOPA Amplifier, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — Fibertek proposes to design, develop, and test a spaceflight prototype 2051 nm thulium (Tm)-doped fiber amplifier (TDFA) optical master oscillator power amplifier...

  19. Studies of highly ionized atoms using internal conversion: 197Au, 57Fe; electric monopole transitions in 40Ca, 42Ca, and 44Ca

    International Nuclear Information System (INIS)

    Ulrickson, M.A.

    1975-01-01

    By using heavy-ion reactions, highly ionized electronic states of atoms may be produced. The interaction between excited nuclear levels and the surrounding atomic electrons via internal conversion allows the nucleus to be used as a probe of the electronic structure of the highly ionized atoms. Studies of such atoms were undertaken for strongly internally converted nuclear levels in 197 Au and 57 Fe. The nuclear levels were Coulomb excited by using 16 O and 32 S beams. Simultaneous measurement of the lifetime of the 77-keV state of 197 Au in both neutral gold atoms and gold atoms with mean charge +10 resulted in a measured change in the internal conversion coefficient of Δalpha/alpha equals - 1.7 +- 3.0)10 -3 . This result is consistent with calculations using a Hartree-Fock--Slater program. Measurements of the electric monopole strengths for 0 + → 0 + transitions were undertaken to determine the amount of core-deformation in calcium nuclei. The E0 strengths for the decays of the 0 + states at 5.21 MeV in 40 C, 1.84 MeV in 42 Ca, and 1.88 MeV in 44 Ca were observed. The branching ratios for the subsequent E0 pair decays were measured by observing the coincident annihilation radiation from the e + member of the pair in coincidence with protons feeding the state in the cases of 42 Ca and 44 Ca, and by observing the actual coincident e + --e - pair together with protons feeding the state in the case of 40 Ca. The resulting E0 strengths (rho less than or equal to 0.06, rho = 0.34 +- 0.03, rho = 0.30 +- 0.10 for 40 Ca, 42 Ca, and 44 Ca respectively) agree with theoretical descriptions

  20. Does LibQUAL+[TM] Account for Student Loyalty to a University College Library?

    Science.gov (United States)

    Helgesen, Oyvind; Nesset, Erik

    2011-01-01

    Purpose: The purpose of this paper is to find out whether LibQUAL+[TM]can account for student loyalty to the library of an institution of higher education. LibQUAL+[TM] is a marketing tool that is used to measure perceived service quality of libraries, and the present analysis aims at validating this service quality instrument within a more…

  1. A conserved aromatic lock for the tryptophan rotameric switch in TM-VI of seven-transmembrane receptors

    DEFF Research Database (Denmark)

    Holst, Birgitte; Nygaard, Rie; Hansen, Louise Valentin

    2010-01-01

    simulations in rhodopsin demonstrated that rotation around the chi1 torsion angle of Trp-VI:13 brings its side chain close to the equally highly conserved Phe-V:13 (Phe-5.47) in TM-V. In the ghrelin receptor, engineering of high affinity metal-ion sites between these positions confirmed their close spatial...... degree as observed in the constructs where Trp-VI:13 itself was mutated, but again without affecting agonist potency. In a proposed active receptor conformation generated by molecular simulations, where the extracellular segment of TM-VI is tilted inwards in the main ligand-binding pocket, Trp-VI:13......The conserved tryptophan in position 13 of TM-VI (Trp-VI:13 or Trp-6.48) of the CWXP motif located at the bottom of the main ligand-binding pocket in TM-VI is believed to function as a rotameric microswitch in the activation process of seven-transmembrane (7TM) receptors. Molecular dynamics...

  2. DiabetterTM Reduces Post Meal Hyperglycemia Via Enhancement Of Glucose Uptake Into Adipocytes And Muscles Cells

    International Nuclear Information System (INIS)

    Zainah Adam; Shafii Khamis

    2014-01-01

    Currently, there are lots of herbal products available in local markets that are used for treatment of diabetes mellitus. Most of these products are not standardized and lack of efficacy and safety data. DiaBetterTM is one of the local herbal products that have been used for treatment of diabetes. This study was carried out to determine the efficacy of DiaBetterTM in reducing hyperglycemia and to elucidate the mechanisms by which hyperglycemia is reduced. Antihyperglycemic evaluation was done in normal and streptozotocin-induced diabetic rats at different prandial states and the antihyperglycemic mechanisms elucidation was carried out in muscle and adipocytes cells using glucose tracer method (2-deoxy-[1-3H]-glucose). The results showed that DiaBetterTM significantly reduced post meal hyperglycemia in normal and diabetic rats, and improved glucose tolerance activity in diabetic rats particularly after 4 and 6 hours of administration. Antihyperglycemic mechanisms elucidation revealed that the DiaBetterTM significantly enhanced insulin-stimulated glucose uptake into adipocytes and muscle cells, with the highest magnitude of enhancement were 1.54-fold (p<0.01) and 1.46-fold (p<0.001), respectively. Molecular mechanisms that responsible for this enhancement were the increment of insulin sensitivity at cells membrane. Cytotoxic evaluation was also done and confirmed that DiaBetterTM was toxicologically safe against muscle and adipocytes cells. In conclusion, post-meal antihyperglycemic and glucose tolerance activity activity of DiaBetterTM was mediated through the enhancement of glucose uptake into adipocytes and muscle cells. Insulin sensitizing activity showed by DiaBetterTM suggests that this product has the potential to ameliorate insulin resistance condition. Therefore, it is suggested that DiaBetterTM can be used as dietary adjunct for the treatment of type 2 diabetes mellitus which related to insulin resistance. (author)

  3. Machine-roomless elevator, SPACEL{sub TM}; Machine roomless elevator SPACEL{sub TM} `Supesuseru{sub TM}`

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    A machine-roomless elevator, SPACEL{sub TM} requiring no machine room, which operates at a rated speed of 45 and 60 m/min, was put on sale in August 1998 with arrangement for passenger use, residential use and bed use. Another elevator operating at a rated speed of 90 and 105 m/min whose travel distance was extended to 75 m was added to the product series and put on sale in February 1999. The control equipment having been installed in a machine room conventionally was modified to a thickness of 100 mm by adopting an inverter device of thin design and densely mounted substrates. The control equipment was installed on the uppermost floor. The winch is a compact and thin type gearless winch incorporating a permanent magnet synchronizing motor, which was installed at the top of the hoistway. These arrangements have realized a machine-roomless elevator. Further system efficiency improvement has achieved energy conservation of about 10% as compared to the conventional rope type and about 80% as compared to the hydraulic type elevators. (translated by NEDO)

  4. Two neutron transfer form factor for the reaction 42Ca(p,t)40Ca

    International Nuclear Information System (INIS)

    Meyer, R.H.

    1978-01-01

    In an attempt to better interpret experimental data concerning the two-neutron pickup process 42 Ca(p,t) 40 Ca, a detailed study of the form factors associated with the reaction is carried out. A set of coupled integro-differential equations describing these form factors is derived, starting from a microscopic, model-independent Hamiltonian. These equations allow contributions to the form factors from hole terms as well as from the particle and so-called ''continuum'' states, which were previously studied. An approximate solution of the form factor equations is obtained by neglecting the coupling terms and expressing the form factor in terms of a set of Sturmian states. Form factors for the transition to the 40 Ca ground state (O 1 + ) are calculated using various sets of Sturmian states. The inclusion of hole states is found to have a major effect upon both the shape of the form factor and the size of the related cross section. Finally, a comparison is made between the O 1 + form factors calculated using Sturmian states and a O 1 + form factor obtained using Sturmian states and a O 1 + form factor obtained using the coexistence model. It is found that a form factor based on Sturmian particle and hole states is very similar to the form factor obtained from the coexistence model calculation

  5. Construction of pTM series plasmids for gene expression in Brucella species.

    Science.gov (United States)

    Tian, Mingxing; Qu, Jing; Bao, Yanqing; Gao, Jianpeng; Liu, Jiameng; Wang, Shaohui; Sun, Yingjie; Ding, Chan; Yu, Shengqing

    2016-04-01

    Brucellosis, the most common widespread zoonotic disease, is caused by Brucella spp., which are facultative, intracellular, Gram-negative bacteria. With the development of molecular biology techniques, more and more virulence-associated factors have been identified in Brucella spp. A suitable plasmid system is an important tool to study virulence genes in Brucella. In this study, we constructed three constitutive replication plasmids (pTM1-Cm, pTM2-Amp, and pTM3-Km) using the replication origin (rep) region derived from the pBBR1-MCS vector. Also, a DNA fragment containing multiple cloning sites (MCSs) and a terminator sequence derived from the pCold vector were produced for complementation of the deleted genes. Besides pGH-6×His, a plasmid containing the groE promoter of Brucella spp. was constructed to express exogenous proteins in Brucella with high efficiency. Furthermore, we constructed the inducible expression plasmid pZT-6×His, containing the tetracycline-inducible promoter pzt1, which can induce expression by the addition of tetracycline in the Brucella culture medium. The constructed pTM series plasmids will play an important role in the functional investigation of Brucella spp. Copyright © 2016 Elsevier B.V. All rights reserved.

  6. Pulsed Tm:YAG laser ablation of knee joint tissues

    Science.gov (United States)

    Shi, Wei-Qiang; Vari, Sandor G.; Duffy, J. T.; Miller, J. M.; Weiss, Andrew B.; Fishbein, Michael C.; Grundfest, Warren S.

    1992-06-01

    We investigated the effect of a free-running 2.01 micron pulsed Tm:YAG laser on bovine knee joint tissues. Ablation rates of fresh fibrocartilage, hyaline cartilage, and bone were measured in saline as a function of laser fluence (160 - 640 J/cm2) and fiber core size (400 and 600 microns). All tissues could be effectively ablated and the ablation rate increased linearly with the increasing fluence. Use of fibers of different core sizes, while maintaining constant energy fluence, did not result in significant difference in ablation rate. Histology analyses of the ablated tissue samples reveal average Tm:YAG radiation induced thermal damage (denatunalization) zones ranging between 130 and 540 microns, depending on the laser parameters and the tissue type.

  7. SpinlineTM, Benefits of a nuclear specific safety-critical digital I/C platform - 15102

    International Nuclear Information System (INIS)

    Duthou, A.; Mouly, P.; Jegou, H.

    2015-01-01

    Spinline TM is Rolls-Royce modular and digital solution dedicated to developing and/or upgrading safety I/C used in nuclear reactors. From the start, Spinline TM was specifically designed for Nuclear applications. Therefore, its architecture and components satisfy, from design, the most stringent safety standards required by the local Safety authorities, while they can be adapted to various types of reactors. This is a significant advantage over suppliers who tried to adapt industrial systems to the Nuclear constraints and faced unexpected delays and costs to meet Safety authorities requirements. Spinline TM was specifically designed to implement any Class 1E and category A IEC-61226 safety I/C functions. It is qualified according to European and French nuclear standard and more recently by the US NRC, notably thanks to its Fail-safe features, deterministic behavior and Physical and Functional Separation. In 2011 EDF chose Spinline TM as its safety I/C systems technology for the modernization of 20 units of its 1300 MW PWR fleet

  8. 42 CFR 460.40 - Violations for which CMS may impose sanctions.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 4 2010-10-01 2010-10-01 false Violations for which CMS may impose sanctions. 460... for which CMS may impose sanctions. In addition to other remedies authorized by law, CMS may impose any of the sanctions specified in §§ 460.42 and 460.46 if CMS determines that a PACE organization...

  9. Landsat TM and ETM+ Kansas Satellite Image Database (KSID)

    Data.gov (United States)

    Kansas Data Access and Support Center — The Kansas Satellite Image Database (KSID):2000-2001 consists of terrain-corrected, precision rectified spring, summer, and fall Landsat 5 Thematic Mapper (TM) and...

  10. Pool boiling performance of Novec{sup TM} 649 engineered fluid

    Energy Technology Data Exchange (ETDEWEB)

    Forrest, Eric; Buongiorno, Jacopo; McKrell, Thomas [Massachusetts Institute of Technology, Cambridge (United States). Dept. of Nuclear Science and Engineering; Hu, Lin-Wen [Massachusetts Institute of Technology, Cambridge (United States). Nuclear Reactor Lab.], e-mail: lwhu@mit.edu

    2009-07-01

    A new fluorinated ketone, C{sub 2}F{sub 5}C(O)CF(CF{sub 3}){sub 2}, is currently being considered as an environmentally friendly alternative for power electronics cooling applications due to its high dielectric strength and low global warming potential (GWP). Sold commercially by the 3M Company as Novec{sup TM} 649 Engineered Fluid, C{sub 2}F{sub 5}C(O)CF(CF{sub 3}){sub 2} exhibits very low acute toxicity while maintaining long-term stability. To assess the general two-phase heat transfer performance of Novec{sup TM} 649, pool boiling tests were conducted by resistively heating a 0.01 in. diameter nickel wire at the fluid's atmospheric saturation temperature of 49 deg C. The nucleate boiling heat transfer coefficient and critical heat flux (CHF) obtained for the fluorinated ketone compare favorably with results obtained for FC-72, a fluorocarbon widely used for the direct cooling of electronic devices. Initial results indicate that Novec{sup TM} 649 may prove to be a viable alternative to FC-72 and other halo alkanes for the cooling of high power density electronic devices. (author)

  11. Theoretical and experimental determination of dosimetric characteristics for ADVANTAGE{sup TM} Pd-103 brachytherapy source

    Energy Technology Data Exchange (ETDEWEB)

    Meigooni, Ali S. [Department of Radiation Medicine, University of Kentucky Medical Center, 800 Rose Street, Lexington, Kentucky 40536 (United States)]. E-mail: alimeig@uky.edu; Dini, Sharifeh A. [Department of Radiation Medicine, University of Kentucky Medical Center, 800 Rose Street, Lexington, Kentucky 40536 (United States); Awan, Shahid B. [Department of Radiation Medicine, University of Kentucky Medical Center, 800 Rose Street, Lexington, Kentucky 40536 (United States); Dou, Kai [Department of Radiation Medicine, University of Kentucky Medical Center, 800 Rose Street, Lexington, Kentucky 40536 (United States); Koona, Rafiq A. [Department of Radiation Medicine, University of Kentucky Medical Center, 800 Rose Street, Lexington, Kentucky 40536 (United States)

    2006-08-15

    ADVANTAGE{sup TM} Pd-103 brachytherapy source has been recently introduced by IsoAid{sup TM} for prostate permanent implants. Dosimetric characteristics (Dose rate constant, radial dose function, 2D-, and 1D-anisotropy functions) of this source model have been determined using both theoretical and experimental methods, following the updated TG-43U1 protocol. Derivation of the dose rate constant was based on recent NIST WAFAC calibration performed in accordance with the 1999 Standards. Measurements were performed in Solid Water{sup TM} using LiF TLD chips and the theoretical calculations were performed in Solid Water{sup TM} and liquid water phantom materials using PTRAN Monte Carlo code. The results of the Monte Carlo simulation have shown a dose rate constant of 0.69 cGy h{sup -1} U{sup -1} in liquid water and 0.67 cGy h{sup -1} U{sup -1} in Solid Water{sup TM} medium. The measured dose rate constant in Solid Water{sup TM} was found to be 0.68{+-}8% cGy h{sup -1} U{sup -1}, which is in a good agreement (within {+-}5%) to the Monte Carlo simulated data. The 2D- and 1D-anisotropy functions of the ADVANTAGE{sup TM} Pd-103 source were calculated for radial distances ranging from 0.5 to 5.0 cm. Radial dose function was determined for radial distances ranging from 0.2 to 8.0 cm using line source approximation. All these calculations are based on L {sub eff} equal to 3.61 cm, calculated following TG-43U1 recommendations. The tabulated data for 2D-anisotropy function, 1D-anisotropy function, dose rate constant and radial dose function have been produced for clinical application of this source model.

  12. Character of the intense 4d. -->. f resonances in atomic La and Tm

    Energy Technology Data Exchange (ETDEWEB)

    Radtke, E R [Bonn Univ. (Germany, F.R.). Physikalisches Inst.

    1979-02-14

    Observations of the 4 d absorption spectra of atomic La and Tm are reported. It is shown that the RPAE predictions for the 4d..-->.. epsilonf cross section in La I are currently closest to experiment. In Tm I a quite sharp autoionising resonance is observed. The differences between the two spectra are discussed with reference to ab initio calculations.

  13. Evaluation of the TEG® platelet mappingTM assay in blood donors

    DEFF Research Database (Denmark)

    Bochsen, Louise; Wiinberg, Bo; Kjelgaard-Hansen, Mads Jens

    2007-01-01

    for quantification of platelet function, including the contribution of the adenosine diphosphate (ADP) and thromboxane A2 (TxA2) receptors to clot formation. Methods In 43 healthy blood donors, the analytical (CVa) and inter-individual variability (CVg) of the TEG® Platelet MappingTM assay were determined together......Background Monitoring of antiplatelet therapy in patients at cardiovascular risk is difficult because existing platelet function tests are too sophisticated for clinical routine. The whole blood TEG® Platelet MappingTM assay measures clot strength as maximal amplitude (MA) and enables...

  14. Measurement of absorbed dose for high energy electron using CaSO4: Tm-PTFE TLD

    International Nuclear Information System (INIS)

    Park, Myeong Hwan; Kim, Do Sung

    2000-01-01

    In this study, the highly sensitive CaSO 4 : Tm-PTFE TLDs has been fabricated for the purpose of measurement of high energy electron. CaSO 4 : Tm phosphor powder was mixed with polytetrafluoroethylene(PTFE) powder and moulded in a disk type(diameter 8.5mm, thickness 90mg/cm 2 ) by cold pressing. The absorbed dose distribution and ranges for high energy electron were measured by using the CaSO 4 : Tm-PTFE TLDs. The ranges determined were R 100 =3D14.5mm, R 50 =3D24.1mm and R p =3D31.8mm, respectively and the beam flatness, the variation of relative dose in 80% of the field size, was 4.5%. The fabricated CaSO 4 : Tm-PTFE TLDs may be utilized in radiation dosimetry for personal, absorbed dose and environmental monitoring.=20

  15. Geophysical drillhole logging of the drillholes OL-KR40, OL-KR41, OL-KR41B, OL-KR42, OLKR42B, OL-KR43 and OL-KR43B, at Olkiluoto 2006 and 2007

    International Nuclear Information System (INIS)

    Tarvainen, A.-M.

    2007-05-01

    Suomen Malmi Oy conducted geophysical borehole logging of the boreholes drillholes OL-KR40, OL-KR41, OL-KR41B, OL-KR42, OL-KR42B, OL-KR43 and OL-KR43B at the Olkiluoto site in Eurajoki during August, September, December 2006 and January 2007. The survey is a part of Posiva Oy's detailed investigation program for the final disposal of spent nuclear fuel. The assignment included the field work and processing of the acoustic data. The report describes field operation, equipment as well as processing procedures and shows the obtained results and an analysis of their quality in the appendices. The raw and processed data are delivered digitally in WellCAD, PDF and Excel format. (orig.)

  16. Effect of co-doping Tm3+ ions on the emission properties of Dy3+ ions in tellurite glasses

    International Nuclear Information System (INIS)

    Sasikala, T.; Rama Moorthy, L.; Mohan Babu, A.; Srinivasa Rao, T.

    2013-01-01

    The present work reports the absorption, photoluminescence and decay properties of singly doped Dy 3+ and co-doped Dy 3+ /Tm 3+ ions in TeO 2 +ZnO+K 2 O+CaO (TZKC) glasses prepared by the melt quenching technique. The glassy nature of the host glass has been confirmed by X-ray diffraction analysis and the primary vibrational modes were determined from the Raman spectrum. Judd–Ofelt (JO) analysis has been used to calculate the radiative transition rates, branching ratios and radiative lifetime of the emitting 4 F 9/2 state. The effect of co-doping of different concentrations of Tm 3+ ions on the emission properties of Dy 3+ ions has been investigated. The decay profiles of the 4 F 9/2 level were fitted to double exponential as well as Inokuti–Hirayama (IH) model to determine the energy transfer rates between Dy 3+ and Tm 3+ ions. The energy transfer rates found to increase with the increase of Tm 3+ ions concentration. The chromaticity coordinates and color purity of the emitted light for all glasses were determined. - Graphical abstract: The graphical abstract shows the emission spectra of Dy 3+ , Tm 3+ and Dy 3+ /Tm 3+ co-doped TZKC glasses recorded by exciting at 355 nm wavelength. - Highlights: • Zinc tellurite glasses doped with Dy 3+ , Tm 3+ and Dy 3+ /Tm 3+ ions were prepared. • XRD, DTA and Raman spectral measurements were recorded to know the nature of host. • Energy transfer occurs from Dy 3+ ions to Tm 3+ ions. • The color purity of the emitted light was determined

  17. Κ-electron capture probability in 167Tm

    International Nuclear Information System (INIS)

    Sree Krishna Murty, G.; Chandrasekhar Rao, M.V.S.; Radha Krishna, K.; Bhuloka Reddy, S.; Satyanarayana, G.; Ramana Rao, P.V.; Sastry, D.L.

    1990-01-01

    The Κ-electron capture probability in the decay of 167 Tm for the first-forbidden transition 1/2 + →3/2 - was measured using the sum-coincidence method and employing a hyper-pure Ge system. The P Κ value is found to be 0.835±0.029, in agreement with the theoretical value of 0.829. (author)

  18. Tunable CW diode-pumped Tm,Ho:YLiF4 laser operating at or near room temperature

    Science.gov (United States)

    Mcguckin, Brendan T. (Inventor); Menzies, Robert T. (Inventor)

    1995-01-01

    A conversion efficiency of 42% and slope efficiency of 60% relative to absorbed pump power are obtained from a continuous wave diode-pumped Tm,Ho:YLiF4 laser at 2 microns with output power of 84 mW at a crystal temperature of 275 K. The emission spectrum is etalon tunable over a range of7 nm (16.3/cm) centered on 2.067 microns with fine tuning capability of the transition frequency with crystal temperature at a measured rate of -0.03/(cm)K. The effective emission cross-section is measured to be 5 x 10(exp -21) cm squared. These and other aspects of the laser performance are disclosed in the context of calculated atmospheric absorption characteristics in this spectral region and potential use in remote sensing applications. Single frequency output and frequency stabilization are achieved using an intracavity etalon in conjunction with an external reference etalon.

  19. Energy transfer and visible-infrared quantum cutting photoluminescence modification in Tm-Yb codoped YPO(4) inverse opal photonic crystals.

    Science.gov (United States)

    Wang, Siqin; Qiu, Jianbei; Wang, Qi; Zhou, Dacheng; Yang, Zhengwen

    2015-08-01

    YPO4:  Tm, Yb inverse opal photonic crystals were successfully synthesized by the colloidal crystal templates method, and the visible-infrared quantum cutting (QC) photoluminescence properties of YPO4:  Tm, Yb inverse opal photonic crystals were investigated. We obtained tetragonal phase YPO4 in all the samples when the samples sintered at 950°C for 5 h. The visible emission intensity of Tm3+ decreased significantly when the photonic bandgap was located at 650 nm under 480 nm excitation. On the contrary, the QC emission intensity of Yb3+ was enhanced as compared with the no photonic bandgap sample. When the photonic bandgap was located at 480 nm, the Yb3+ and Tm3+ light-emitting intensity weakened at the same time. We demonstrated that the energy transfer between Tm3+ and Yb3+ is enhanced by the suppression of the red emission of Tm3+. Additionally, the mechanisms for the influence of the photonic bandgap on the energy transfer process of the Tm3+, Yb3+ codoped YPO4 inverse opal are discussed.

  20. Lightweight Metal RubberTM Sensors and Interconnects, Phase II

    Data.gov (United States)

    National Aeronautics and Space Administration — The objective of this NASA Phase II program is to develop and increase the Technology Readiness Level of multifunctional Metal RubberTM (MRTM) materials that can be...

  1. 75 FR 5071 - Mississippi L&D 21, LLC, Mississippi River No. 21 Hydropower Company Lock + TM

    Science.gov (United States)

    2010-02-01

    ... Lock + \\TM\\ Hydro Friends Fund XXXII, LLC; Notice of Preliminary Permit Applications Accepted for..., Lock + TM Hydro Friends Fund XXXII, LLC (Lock + Hydro) filed an application for a preliminary permit...

  2. The new 157Tm isotope, Tsub(1/2)=(3.6+-0.3) min

    International Nuclear Information System (INIS)

    Latuszynski, A.; Mikulski, J.; Potempa, A.W.; Zielinski, A.; Zuber, K.; Penev, I.; Zuber, J.

    1975-01-01

    The new isotope 157 Tm was discovered, and its half-life Tsub(1/2) (3.6+-0.3)min was measured. On the basis of the balance of energies and intensities of γ-transitions occurring in the 157 Tm decay a number of excited states of the 157 Er nucleus with energies of 110.2; 241.3; 357.3 and 457.1 keV were found. (author)

  3. Magnetic phase diagram of HoxTm1-x alloys

    DEFF Research Database (Denmark)

    Sarthour, R.S.; Cowley, R.A.; Ward, R.C.C.

    2000-01-01

    The magnetic phase diagram of the competing anisotropy system, Ho/Tm, has been determined by neutron-scattering techniques and the results compared with calculations based on a mean-field model. The crystal-field interactions in Ho favor alignment of the magnetic moments in the basal plane whereas......, with long-range order, were identified and the magnetic phase diagram, including a pentacritical point, determined. A mean-field model was used to explain the results and the results are in good agreement with the experimental results....... in Tm they favor alignment along the c axis. Single-crystal alloys were grown with molecular-beam epitaxy techniques in Oxford. The components of the magnetic moment alone the c direction and in the basal plane were determined from the neutron-scattering measurements. Five distinct magnetic phases...

  4. Decruding of PWR Fuel with the ICEDEC{sup TM} technique

    Energy Technology Data Exchange (ETDEWEB)

    Ivars, Roland; Fredriksson, Eva; Rosengren, Anders; Hallgren, Peter [Westinghouse Atom AB, Uppsala (Sweden)

    2002-04-15

    The novel fuel decontamination system ICEDEC{sup TM} utilizes a mixture of ice particles and water circulating through the assembly for scraping off loose crud from the fuel surfaces. Initially, ICEDEC{sup TM} was developed for BWRs. By means of fuel decontamination the origin of the personnel radiation exposure, i. e. the loose fuel crud, can be decreased. The technique can be used for radiation level reduction, eliminating the AOA (Axial Offset anomaly) problem or general decruding purposes. Decontamination tests of burned out and two-year-old fuel in the BWR Ringhals 1 in Sweden verified that ICEDEC{sup TM} maintained the mechanical integrity of the fuel and fulfilled the very important criteria; only the loose crud was removed and the oxide layer was not affected. Activity measurements prior to and after the decontamination, showed that more than 50% of the loose crud was removed from the fuel surfaces. For PWR the condition of maintained boron level in the pool water is a prerequisite. This can be achieved by utilizing a closed loop system with a water reservoir. From the reservoir water is used for the production of the ice particles. After removal of the loose crud from the fuel the crud/ice/water slurry is separated in a specially designed filter unit. The melted ice and residual water is then transported back to the water reservoir. Other methods could be to add boron equivalent to the excess water from the melted ice or use reverse osmosis to separate the boron and water in the pool. Including an application study followed by preliminary and detailed designs and manufacture and testing a PWR ICEDEC{sup TM} system can be licensed after two years.

  5. Theoretical and experimental determination of dosimetric characteristics for brachyseedTM Pd-103, model Pd-1, source

    International Nuclear Information System (INIS)

    Meigooni, A.S.; Zhang Hualin; Perry, Candace; Dini, S.A.; Koona, R.A.

    2003-01-01

    Dosimetric characteristics of the BrachySeed TM Pd-103, Model Pd-1 source have been determined using both theoretical and experimental methods. Dose rate constant, radial dose function, and anisotropy functions of the source have been obtained following the TG-43 recommendations. Derivation of the dose rate constant was based on recent NIST WAFAC calibration performed in accordance with their 1999 Standard. Measurements were performed in Solid Water TM using LiF TLD chips. Theoretical simulation calculations were performed in both Solid Water TM and water phantom materials using MCNP4C2 Monte Carlo code using DLC-200 interaction data. The results of the Monte Carlo simulation indicated a dose rate constant of 0.65 cGy h -1 U -1 and 0.61 cGy h -1 U -1 in water and Solid Water TM , respectively. The measured dose rate constant in Solid Water TM was found to be 0.63±7% cGy h -1 U -1 , which is within the experimental uncertainty of the Monte-Carlo simulated results. The anisotropy functions of the source were calculated in both water and in Solid Water TM at the radial distances of 1 to 7 cm. Measurements were made in Solid Water TM at distances of 2, 3, 5, and 7 cm. The Monte-Carlo calculated anisotropy constant of the new source was found to be 0.98 in water. The tabulated data and 5th order polynomial fit coefficients for the radial dose function along with the dose rate constant and anisotropy functions are provided to support clinical use of this source

  6. Role of ID Proteins in BMP4 Inhibition of Profibrotic Effects of TGF-β2 in Human TM Cells.

    Science.gov (United States)

    Mody, Avani A; Wordinger, Robert J; Clark, Abbot F

    2017-02-01

    Increased expression of TGF-β2 in primary open-angle glaucoma (POAG) aqueous humor (AH) and trabecular meshwork (TM) causes deposition of extracellular matrix (ECM) in the TM and elevated IOP. Bone morphogenetic proteins (BMPs) regulate TGF-β2-induced ECM production. The underlying mechanism for BMP4 inhibition of TGF-β2-induced fibrosis remains undetermined. Bone morphogenic protein 4 induces inhibitor of DNA binding proteins (ID1, ID3), which suppress transcription factor activities to regulate gene expression. Our study will determine whether ID1and ID3 proteins are downstream targets of BMP4, which attenuates TGF-β2 induction of ECM proteins in TM cells. Primary human TM cells were treated with BMP4, and ID1 and ID3 mRNA, and protein expression was determined by quantitative PCR (Q-PCR) and Western immunoblotting. Intracellular ID1 and ID3 protein localization was studied by immunocytochemistry. Transformed human TM cells (GTM3 cells) were transfected with ID1 or ID3 expression vectors to determine their potential inhibitory effects on TGF-β2-induced fibronectin and plasminogen activator inhibitor-I (PAI-1) protein expression. Basal expression of ID1-3 was detected in primary human TM cells. Bone morphogenic protein 4 significantly induced early expression of ID1 and ID3 mRNA (P protein in primary TM cells, and a BMP receptor inhibitor blocked this induction. Overexpression of ID1 and ID3 significantly inhibited TGF-β2-induced expression of fibronectin and PAI-1 in TM cells (P protein 4 induced ID1 and ID3 expression suppresses TGF-β2 profibrotic activity in human TM cells. In the future, targeting specific regulators may control the TGF-β2 profibrotic effects on the TM, leading to disease modifying IOP lowering therapies.

  7. Exploring TM image texture and its relationships with biomass estimation in Rondônia, Brazilian Amazon Explorando texturas de imagens TM e suas relações com estimativas de biomassa em Rondônia

    Directory of Open Access Journals (Sweden)

    Dengsheng Lu

    2005-06-01

    Full Text Available Many texture measures have been developed and used for improving land-cover classification accuracy, but rarely has research examined the role of textures in improving the performance of aboveground biomass estimations. The relationship between texture and biomass is poorly understood. This paper used Landsat Thematic Mapper (TM data to explore relationships between TM image textures and aboveground biomass in Rondônia, Brazilian Amazon. Eight grey level co-occurrence matrix (GLCM based texture measures (i.e., mean, variance, homogeneity, contrast, dissimilarity, entropy, second moment, and correlation, associated with seven different window sizes (5x5, 7x7, 9x9, 11x11, 15x15, 19x19, and 25x25, and five TM bands (TM 2, 3, 4, 5, and 7 were analyzed. Pearson's correlation coefficient was used to analyze texture and biomass relationships. This research indicates that most textures are weakly correlated with successional vegetation biomass, but some textures are significantly correlated with mature forest biomass. In contrast, TM spectral signatures are significantly correlated with successional vegetation biomass, but weakly correlated with mature forest biomass. Our findings imply that textures may be critical in improving mature forest biomass estimation, but relatively less important for successional vegetation biomass estimation.Muitas medidas de textura têm sido desenvolvidas e utilizadas para melhorar a acurácia de classificações de cobertura das terras, mas raramente têm-se avaliado a importância dessas medidas em estimativas de biomassa. Este trabalho utilizou dados Landsat TM para explorar as relações entre texturas de imagens TM e biomassa em Rondônia, Amazônia. Foram analisadas oito medidas de textura baseadas em matrizes de co-ocorrência de tons de cinza (i.e., média, variância, homogeneidade, contraste, dissimilaridade, entropia, segundo momento e correlação, associadas com sete diferentes tamanhos de janela (5x5, 7x7

  8. Autosomal SNP typing of forensic samples with the GenPlex(TM) HID System: Results of a collaborative study

    DEFF Research Database (Denmark)

    Tomas, C.; Axler-DiPerte, G.; Budimlija, Z.M.

    2011-01-01

    in Europe and 5 in the US) in order to test the robustness and reliability of the GenPlex(TM) HID System on forensic samples. Three samples with partly degraded DNA and 10 samples with low amounts of DNA were analyzed in duplicates using various amounts of DNA. In order to compare the performance of the Gen......Plex(TM) HID System with the most commonly used STR kits, 500 pg of partly degraded DNA from three samples was typed by the laboratories using one or more STR kits. The median SNP typing success rate was 92.3% with 500 pg of partly degraded DNA. Three of the fourteen laboratories counted for more than two...... was the least successful. With the exception of the MiniFiler(TM) kit (AB), GenPlex(TM) HID performed better than five other tested STR kits. When partly degraded DNA was analyzed, GenPlex(TM) HID showed a very low mean mach probability, while all STR kits except MiniFiler(TM) had very limited discriminatory...

  9. A comparison between the electronic magnification (EM) and true magnification (TM) of breast phantom images using a CDMAM phantom

    International Nuclear Information System (INIS)

    Vahey, Karou; Ryan, Elaine; McLean, Don; Poulos, Ann; Rickard, Mary

    2012-01-01

    Purpose: To provide a comparison between the image quality of electronically magnified (EM) and geometric, or true, magnification (TM) mammographic images. Materials and methods: One Computed Radiography (CR), one Digital Radiography (DR) and two screen–film (S–F) imaging systems were investigated. A Contrast-Detail Mammography (CDMAM) phantom was used as a test object. Three contact images and three sets of TM images with a magnification factor of 1.8 were taken on all systems. Software was used to zoom the contact images by a factor of 1.8 to produce EM images. Two observers evaluated all of the images. An Image Quality Figure and contrast detail curve were used to analyze the observer data and Mann–Whitney U-tests were performed to determine the statistical significance of the results. Results: No significant differences were found between soft copy and hard copy for any imaging modality. No significant difference in contrast detail detectability (CDD) was seen between EM images from the two digital systems and TM images on S–F systems. The results for the DR EM images and S–F TM images also showed no differences. The CDD of DR TM images was significantly better than both EM and S–F TM images. Conclusion: Digitally zoomed images offer the same level of CDD as S–F TM images, and so may be viably used in their place. DR systems offer greater CDD than conventional S–F images, when comparing the TM images. This implies that doses can be greatly reduced for TM views using DR systems, while maintaining acceptable image quality.

  10. Optical properties of GaS:Ho3+ and GaS:Tm3+ single crystals

    International Nuclear Information System (INIS)

    Jin, Moon-Seog; Kim, Chang-Dae; Kim, Wha-Tek

    2004-01-01

    GaS:Ho 3+ and GaS:Tm 3+ single crystals were grown by using the chemical transport reaction method. We measured the optical absorption, the infra-red absorption, and the photoluminescence spectra of the single crystals. The direct and the indirect energy band gaps of the single crystals at 13 K were identified. Infra-red absorption peaks at 6 K appeared in the single crystals. Broad emission bands at 6 K were observed at 464 nm and 580 nm for GaS:Ho 3+ and 462 nm and 581 nm for GaS:Tm 3+ . These broad emission bands were identified as originating from donor-acceptor pair recombinations. Sharp emission peak groups were observed near 435 nm, 495 nm, and 660 nm for GaS:Ho 3+ and near 672 nm for GaS:Tm 3+ . These sharp emission peak groups were identified as being due to the electron transitions between the energy levels of Ho 3+ and Tm 3+ . Especially, white photoluminescence was obtained in the GaS:Ho 3+ single crystal.

  11. Relações empíricas entre características dendrométricas da Caatinga brasileira e dados TM Landsat 5

    Directory of Open Access Journals (Sweden)

    André Quintão de Almeida

    2014-04-01

    Full Text Available O objetivo deste trabalho foi ajustar modelos para estimar características dendrométricas da Caatinga brasileira a partir de dados do sensor TM do Landsat 5. Medidas de diâmetro e altura das árvores foram obtidas de 60 parcelas de inventário (400 m2, em dois municípios do Estado de Sergipe. A área basal e o volume de madeira foram estimados com uso de equação alométrica e de fator de forma (f = 0,9. As variáveis explicativas foram obtidas do sensor TM, após correção radiométrica e geométrica, tendo-se considerado, na análise, seis bandas espectrais, com resolução espacial de 30 m, além dos índices de razão simples (SR, de vegetação por diferença normalizada (NDVI e de vegetação ajustado ao solo (Savi. Na escolha das melhores variáveis explicativas, foram considerados coeficiente de determinação (R2, raiz do erro quadrático médio (RMSE e critério bayesiano de informação (CBI. A área basal por hectare não apresentou correlação significativa com nenhuma das variáveis explicativas utilizadas. Os melhores modelos foram ajustados à altura média das árvores por parcela (R2 = 0,4; RMSE = 13% e ao volume de madeira por hectare (R2 = 0,6; RMSE = 42%. As métricas derivadas do sensor TM do Landsat 5 têm grande potencial para explicar variações de altura média das árvores e do volume de madeira por hectare, em remanescentes de Caatinga situados no Nordeste brasileiro.

  12. Proton Radioactivity Measurements at HRIBF: Ho, Lu, and Tm Isotopes

    International Nuclear Information System (INIS)

    Akovali, Y.; Batchelder, J.C.; Bingham, C.R.; Davinson, T.; Ginter, T.N.; Gross, C.J.; Grzywacz, R.; Hamilton, J.H.; Janas, Z.; Karny, M.; Kim, S.H.; MacDonald, B.D.; Mas, J.F.; McConnell, J.W.; Piechaczek, A.; Ressler, J.J.; Rykaczewski, K.; Slinger, R.C.; Szerypo, J.; Toth, K.S.; Weintraub, W.; Woods, P.J.; Yu, C.-H.; Zganjar, E.F.

    1998-01-01

    Two new isotopes, 145 Tm and 140 Ho and three isomers in previously known isotopes, 141m Ho, 150m Lu and 151m Lu have been discovered and studied via their decay by proton emission. These proton emitters were produced at the Holifield Radioactive Ion Beam Facility (HRIBF) by heavy-ion fusion-evaporation reactions, separated in A/Q with a recoil mass spectrometer (RMS), and detected in a double-sided silicon strip detector (DSSD). The decay energy and half-life was measured for each new emitter. An analysis in terms of a spherical shell model is applied to the Tm and Lu nuclei, but Ho is considerably deformed and requires a collective model interpretation

  13. Cubic to tetragonal phase transition of Tm3+ doped nanocrystals in oxyfluoride glass ceramics

    International Nuclear Information System (INIS)

    Li, Yiming; Fu, Yuting; Shi, Yahui; Zhang, Xiaoyu; Yu, Hua; Zhao, Lijuan

    2016-01-01

    Tm 3+ ions doped β-PbF 2 nanocrystals in oxyfluoride glass ceramics with different doping concentrations and thermal temperatures are prepared by a traditional melt-quenching and thermal treatment method to investigate the structure and the phase transition of Tm 3+ doped nanocrystals. The structures are characterized by X-ray diffraction Rietveld analysis and confirmed with numerical simulation. The phase transitions are proved further by the emission spectra. Both of the doping concentration and thermal temperature can induce an O h to D 4h site symmetry distortion and a cubic to tetragonal phase transition. The luminescence of Tm 3+ doped nanocrystals at 800 nm was modulated by the phase transition of the surrounding crystal field

  14. Wavelength switchable high-power diode-side-pumped rod Tm:YAG Laser around 2µm.

    Science.gov (United States)

    Wang, Caili; Du, Shifeng; Niu, Yanxiong; Wang, Zhichao; Zhang, Chao; Bian, Qi; Guo, Chuan; Xu, Jialin; Bo, Yong; Peng, Qinjun; Cui, Dafu; Zhang, Jingyuan; Lei, Wenqiang; Xu, Zuyan

    2013-03-25

    We report a high-power diode-side-pumped rod Tm:YAG laser operated at either 2.07 or 2.02 µm depending on the transmission of pumped output coupler. The laser yields 115W of continuous-wave output power at 2.07 µm with 5% output coupling, which is the highest output power for all solid-state 2.07 μm cw rod Tm:YAG laser reported so far. With an output coupler of 10% transmission, the center wavelength of the laser is switched to 2.02 μm with an output power of 77.1 W. This is the first observation of high-power wavelength switchable diode-side-pumped rod Tm:YAG laser around 2 µm.

  15. 75 FR 75868 - Airworthiness Directives; Diamond Aircraft Industries GmbH Models DA 40 and DA 40F Airplanes

    Science.gov (United States)

    2010-12-07

    ... Airworthiness Directives; Diamond Aircraft Industries GmbH Models DA 40 and DA 40F Airplanes AGENCY: Federal... of the Thielert Engine Owners Group commented that the Model DA 42 has the same door design and the same unsafe condition. He recommended that the AD also apply to the Model DA 42. The FAA has discussed...

  16. Evaluation of the MoleMateTM training program for assessment of suspicious pigmented lesions in primary care

    Directory of Open Access Journals (Sweden)

    Annabel Wood

    2008-05-01

    Conclusion The MoleMateTM training program is a potentially effective and acceptable informatics tool to teach practitioners to recognise the features of SPLs identified by the MoleMateTM system. It will be used as part of the intervention in a randomised controlled trial to compare the diagnostic accuracy and appropriate referral rates of practitioners using the MoleMateTM system with best practice in primary care.

  17. Crystal growth, spectroscopic characterization and laser performance of Tm/Mg:LiNbO3 crystal

    Science.gov (United States)

    Zhang, P. X.; Yin, J. G.; Zhang, R.; Li, H. Q.; Xu, J. Q.; Hang, Y.

    2014-03-01

    A Tm, Mg co-doped LiNbO3 crystal was grown by the traditional Czochralski method. The room-temperature absorption, photo-luminescence spectra and fluorescence lifetime of Tm3+ ions in the crystal have been investigated. The experimental results show that the co-doped of MgO can lead to the lengthening of the measured fluorescence lifetime of the upper Tm3+:3F4 level. Based on the Judd-Ofelt approach, the intensity parameters Ω2,4,6 of Tm3+ were calculated to be Ω2 (6.29 × 10-20 cm2), Ω4 (0.54 × 10-20 cm2) and Ω6 (0.79 × 10-20 cm2). Other spectroscopic parameters that relate to laser performance were also obtained. Non-photorefractive continuous wave laser operation with a Tm, Mg:LiNbO3 single crystal is demonstrated at room temperature for the first time. We obtained 1.026 W output power at 1.885 μm with a slope efficiency of near 14%, which, to the best of our knowledge, is the largest output power and the highest slope efficiency obtained for this crystal thus far. The output power was observed to be stable, and the crystal showed no sign of photorefractive damage.

  18. New polyamide 12 grades for large diameter oil and pipes: VESTAMID{sup TM} LX9020 and VESTAMID{sup TM} LX9030

    Energy Technology Data Exchange (ETDEWEB)

    Dowe, Andreas; Baron, Christian; Coelho, Germano [Evonik Degussa GmbH, Arlington Heights, IL(United States)

    2008-07-01

    Polyamide 12 (PA 12) is a high performance polymer with outstanding mechanical properties and excellent chemical stability. It is the preferred material in many demanding applications, e. g. in the automotive industry for fuel lines of passenger cars or for air brake tubing's in trucks. In recent years PA 12 pipes underwent an approval process for the use in high-pressure gas distribution and offshore oil explorations. Also the applications lining and rehabilitation of pipes are under investigation. Especially the swelling behavior and the outstanding resistance to oil and other petrochemicals make VESTAMID{sup TM} the material of choice for rehabilitation and lining applications. The authors will give an introduction to the excellent technical performance of PA 12. The very high melt viscosity and stiffness of the newly developed VESTAMID{sup TM} grades enables new applications of PA 12 in oil and gas applications which will be discussed in this paper. (author)

  19. Stages of driving behavior change within the Transtheoretical Model (TM).

    Science.gov (United States)

    Kowalski, Kristina; Jeznach, Anna; Tuokko, Holly Anna

    2014-09-01

    Many older adults voluntarily restrict their driving or stop driving of their own accord. Driving behavior change may occur in stages, as predicted by the Transtheoretical Model of Behavior Change (TM). This study explored the process of older driver behavior change within the TM framework using interviews/focus groups with drivers and former drivers aged 71-94 years. Within those groups of drivers, driving behavior was divided into two classes: those who changed their driving with age and those who did not. Those who changed their driving as they aged included people gradually imposing restrictions ("gradual restrictors") and those making plans in anticipation of stopping driving ("preparers"). Participants who did not change their driving included those who employed lifelong driving restrictions ("consistent") and those who made no changes ("non-changers"). Preliminary support for TM within the driving context was found; however, further exploration of driving behavior change within this framework is warranted. It is important to continue to investigate the factors that might influence driving behavior in older adults. By promoting self-regulation in individuals, it may be possible to help older adults continue to drive, thereby improving older adult's mobility and quality of life. Copyright © 2014 National Safety Council and Elsevier Ltd. All rights reserved.

  20. Compact self-Q-switched Tm:YLF laser at 1.91 μm

    Science.gov (United States)

    Zhang, B.; Li, L.; He, C. J.; Tian, F. J.; Yang, X. T.; Cui, J. H.; Zhang, J. Z.; Sun, W. M.

    2018-03-01

    We report self-Q-switching operation in a diode-pumped Tm:YLF bulk laser by exploiting saturable re-absorption under the quasi-three-level regime. Robust self-Q-switched pulse output at 1.91 μm in fundamental mode is demonstrated experimentally with 1.5 at.% doped Tm:YLF crystal. At maximum absorbed pump power of 4.5 W, the average output power and pulse energy are obtained as high as 610 mW and 29 μJ, respectively, with the corresponding slope efficiency of 22%. Pulse repetition rate is tunable in the range of 3-21 kHz with changing the pump power. The dynamics of self-Q-switching of Tm:YLF laser are discussed with the help of a rate equation model showing good agreement with the experiment. The compact self-Q-switched laser near 2 μm has potential application in laser radar systems for accurate wind velocity measurements.

  1. Visible and near infrared up-conversion luminescence in Yb3+/Tm3+ co-doped yttria-alumino-silicate glass based optical fibers

    International Nuclear Information System (INIS)

    Halder, Arindam; Chandra Paul, Mukul; Wadi Harun, Sulaiman; Kumar Bhadra, Shyamal; Bysakh, Sandip; Das, Shyamal; Pal, Mrinmay

    2013-01-01

    We report blue light up-conversion (UC) emission in Yb–Tm co-doped nano-phase separated yttria-alumino-silicate (YAS) glass based D-shaped with low-index cladding optical fibers. Y 2 O 3 creates an environment of nano structured YAS glass phases with Yb and Tm rich zone into the core glass which confirmed from TEM analyses. This kind of glass host assists in distributing of Yb and Tm rich zone uniformly throughout the core region. Yb and Tm doped regions exist mainly into nano YAS phases, defined as RE rich nano YAS-RE phases. All samples exhibit UC luminescence peaks at 483 nm, 650 nm and 817 nm for Tm 3+ and 1044 nm for Yb 3+ under excitation by 975 nm laser light. In such type of nano-engineered glass–ceramic based host, almost all the Yb ions transferred its energy to the nearer Tm ions. In particular 483 nm emission is attributed to 1 G 4 → 3 H 6 transition through a three step resonance energy transfer (ET) from excited Yb 3+ . The highest emission intensity is obtained with a concentration of 0.5 wt% Tm 3+ and 2.0 wt% Yb 3+ . The ET between Yb 3+ and Tm 3+ is increased with increase of Yb 3+ concentration with respect to Tm 3+ . The experimental fluorescence life-times of Tm 3+ upconversion emission at visible wavelengths into such kind of fiber is reported under 975 nm pump excitation. The present study is important for development of an efficient tunable 483 nm fluorescence light source. -- Highlights: • We report nano-phase separated YAS glass host based Yb–Tm co-doped optical fibers. • Almost all the Yb transferred its energy to the neighboring Tm ions. • We report strong UC luminescence peaks at 483 nm and 817 nm wavelengths. • We report third ET coefficient as 1.6723 Hz for such kind of Yb–Tm codoped fiber. • We report suitable fiber as an efficient tunable 483 nm fluorescence light source

  2. High luminance LCD projection TV, 40ZIP; Kokido ekisho projection terebi 40ZIP

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    A 40 type LCD projection TV was commercialized which utilized the characteristics of a `large screen`, `saved space` and `light weight` incident to an LCD projection system and which succeeded `a television benign to people`, the concept of a flat wide television FACE{sub TM}. The main features are as follows:(1) A bright-in-every-corner and high-definition picture realized by employing a 2.7 type low temperature polysilicon LCD panel, high performance optical unit, wide angle of visibility, and high contrast screen. (2) A slim design for a 40 type large screen (compared with conventional models at Toshiba) having a depth comparable to that of 14 type and a mass equivalent to that of 25 type.(3) A PC input terminal most suitable for presentation. (translated by NEDO)

  3. Molecular cloning and characterization of autophagy-related gene TmATG8 in Listeria-invaded hemocytes of Tenebrio molitor.

    Science.gov (United States)

    Tindwa, Hamisi; Jo, Yong Hun; Patnaik, Bharat Bhusan; Lee, Yong Seok; Kang, Sang Sun; Han, Yeon Soo

    2015-07-01

    Macroautophagy (hereinafter called autophagy) is a highly regulated process used by eukaryotic cells to digest portions of the cytoplasm that remodels and recycles nutrients and disposes of unwanted cytoplasmic constituents. Currently 36 autophagy-related genes (ATG) and their homologs have been characterized in yeast and higher eukaryotes, including insects. In the present study, we identified and functionally characterized the immune function of an ATG8 homolog in a coleopteran insect, Tenebrio molitor (TmATG8). The cDNA of TmATG8 comprises of an ORF of 363 bp that encodes a protein of 120 amino acid residues. TmATG8 transcripts are detected in all the developmental stages analyzed. TmAtg8 protein contains a highly conserved C-terminal glycine residue (Gly116) and shows high amino acid sequence identity (98%) to its Tribolium castaneum homolog, TcAtg8. Loss of function of TmATG8 by RNAi led to a significant increase in the mortality rates of T. molitor larvae against Listeria monocytogenes. Unlike dsEGFP-treated control larvae, TmATG8-silenced larvae failed to turn-on autophagy in hemocytes after injection with L. monocytogenes. These data suggest that TmATG8 play a role in mediating autophagy-based clearance of Listeria in T. molitor. Copyright © 2015 Elsevier Ltd. All rights reserved.

  4. Aged interleukin-10tm1Cgn chronically inflamed mice have substantially reduced fat mass, metabolic rate, and adipokines.

    Directory of Open Access Journals (Sweden)

    Reyhan M Westbrook

    Full Text Available Interleukin 10tm1Cgn (IL 10tm mice have been utilized as a model of chronic inflammation and declining health span because of their propensity to develop chronic activation in NFkB pathways, skeletal muscle and cardiac changes, and mitochondrial dysfunction. We hypothesized that older IL 10tm frail mice would have alterations similar to frail, older humans in measured parameters of glucose metabolism, oxygen consumption (VO2, respiratory quotient (RQ, spontaneous locomotor activity, body composition and plasma adipokine levels. To test this hypothesis, we investigated these metabolic parameters in cohorts of 3, 10, and 20 month old IL 10tm female mice and age and gender matched C57Bl/6 mice. Insulin sensitivity, glucose homeostasis, locomotor activity and RQ were not significantly altered between the two strains of mice. Interestingly, old IL 10tm mice had significantly decreased VO2 when normalized by lean mass, but not when normalized by fat mass or the lean/fat mass ratio. NMR based body composition analysis and dissection weights show that fat mass is decreased with age in IL 10tm mice compared to controls. Further, plasma adiponectin and leptin were also decreased in IL 10tm.These findings suggest that frailty observed in this mouse model of chronic inflammation may in part be driven by alterations in fat mass, hormone secretion and energy metabolism.

  5. tmRNA-mediated trans-translation as the major ribosome rescue system in a bacterial cell

    Directory of Open Access Journals (Sweden)

    Hyouta eHimeno

    2014-04-01

    Full Text Available tmRNA (transfer messenger RNA; also known as 10Sa RNA or SsrA RNA is a small RNA molecule that is conserved among bacteria. It has structural and functional similarities to tRNA: it has an upper half of the tRNA-like structure, its 5’ end is processed by RNase P, it has typical tRNA-specific base modifications, it is aminoacylated with alanine, it binds to EF-Tu after aminoacylation and it enters the ribosome with EF-Tu and GTP. However, tmRNA lacks an anticodon, and instead it has a coding sequence for a short peptide called tag-peptide. An elaborate interplay of actions of tmRNA as both tRNA and mRNA with the help of a tmRNA-binding protein, SmpB, facilitates trans-translation, which produces a single polypeptide from two mRNA molecules. Initially alanyl-tmRNA in complex with EF-Tu and SmpB enters the vacant A-site of the stalled ribosome like aminoacyl-tRNA but without a codon-anticodon interaction, and subsequently truncated mRNA is replaced with the tag-encoding region of tmRNA. During these processes, not only tmRNA but also SmpB structurally and functionally mimics both tRNA and mRNA. Thus trans-translation rescues the stalled ribosome, thereby allowing recycling of the ribosome. Since the tag-peptide serves as a target of AAA+ proteases, the trans-translation products are preferentially degraded so that they do not accumulate in the cell. Although alternative rescue systems have recently been revealed, trans-translation is the only system that universally exists in bacteria. Furthermore, it is unique in that it employs a small RNA and that it prevents accumulation of nonfunctional proteins from truncated mRNA in the cell. It might play the major role in rescuing the stalled translation in the bacterial cell.

  6. Powernext futuresTM back office user's guide

    International Nuclear Information System (INIS)

    2005-05-01

    The introduction of a power exchange in France is a direct response to the opening up of the European electricity markets. Powernext SA is a Multilateral Trading Facility in charge of managing the French power exchange through an optional and anonymous organised exchange offering: - Day-ahead contracts for the management of volume risk on Powernext Day-Ahead TM since 21 November 2001, - Medium term contracts for the management of price risk on Powernext Futures TM since 18 June 2004. This document is the back office user's guide, it presents: the market model (specifications, regulation, legal framework), the members (traders, clearers, quotation providers, fees structure), the products (specifications, use, liquidity and market efficiency), the clearing (recording transactions, risk management before delivery period, last settlement of contracts, risk management during delivery, additional margin, examples, default management), the LCH.Clearnet Ltd clearing system (hardware and software requirements, setup of the VPN client software, functionalities, market information disclosure), the delivery (nomination, file characteristics and transmission), the payment (financial flows, eligible assets provided to cover margin requirements). ECS reports, treasury documents, contracts codification, FTP server arborescence, latent and carried-out margins and a glossary are given in the appendix. (J.S.)

  7. BOREAS RSS-7 Landsat TM LAI IMages of the SSA and NSA

    Science.gov (United States)

    Hall, Forrest G. (Editor); Nickeson, Jaime (Editor); Chen, Jing; Cihlar, Josef

    2000-01-01

    The BOReal Ecosystem-Atmosphere Study Remote Sensing Science (BOREAS RSS-7) team used Landsat Thematic Mapper (TM) images processed at CCRS to produce images of Leaf Area Index (LAI) for the BOREAS study areas. Two images acquired on 06-Jun and 09-Aug-1991 were used for the SSA, and one image acquired on 09-Jun-1994 was used for the NSA. The LAI images are based on ground measurements and Landsat TM Reduced Simple Ratio (RSR) images. The data are stored in binary image-format files.

  8. Nuclear density distributions of 40,42,44,48Ca from elastic scattering of 104 MeV alpha particles

    International Nuclear Information System (INIS)

    Gils, H.J.; Friedman, E.; Majka, Z.

    1979-12-01

    The elastic scattering of 104 MeV α particles from 40 , 42 , 44 , 48 Ca has been analyzed by a single folding model with a density dependent effective interaction. Nuclear density distributions have been extracted using various descriptions including Fourier-Bessel series which distinctly reduces the model dependence of the results and enables realistic estimates of errors. Differences of the density shapes of the Ca-isotopes are well determined showing evidence for a neutron skin in 48 Ca. The resulting root mean square radii are compared to the results obtained from other methods. The sensitivity and limitations of various methods are discussed. (orig.) 891 KBE/orig. 892 BRE

  9. Study of the decay scheme of 159Tm

    International Nuclear Information System (INIS)

    Aguer, Pierre; Bastin, Genevieve; Chin Fan Liang; Libert, Jean; Paris, Pierre; Peghaire, Alain

    1975-01-01

    The energy levels of 159 Er have been investigated from the decay of 159 Tm (T(1/2)=9mn). Samples were obtained by (p,xn) reaction and on-line separation through Isocele facility. A level scheme is proposed with 24 levels between 0 and 1.3MeV [fr

  10. Optical Spectra Properties and Continuous-Wave Laser Performance of Tm,Y:CaF2 Single Crystals

    Directory of Open Access Journals (Sweden)

    Jingxin Ding

    2018-01-01

    Full Text Available 3 at.% Tm, x at.% Y:CaF2 crystals (x=0, 0.5, 1, 2, and 3 were grown by the vertical Bridgman method and investigated. Codoping Y3+ ions can manipulate the local structure of Tm3+ ions in the CaF2 crystal and then improve the spectroscopic properties. Compared with 3 at.% Tm:CaF2, 3 at.% Tm, 3 at.% Y:CaF2 crystal has several advantages. Firstly, the absorption cross section is improved from 0.35 × 10−20 cm−2 to 0.45 × 10−20 cm−2 at 767 nm, and the fluorescence intensity had elevated 3.4 times. Secondly, the linewidth of the fluorescence spectrum and lifetime also increased from 164 nm to 191 nm and from 6.16 ms to 8.15 ms at room temperature, respectively. Furthermore, quantum efficiency improved from 58.2% to 80.3%. The maximum laser output power of 583 mW and slope efficiency of 25.3% were achieved in 3 at.% Tm, 3 at.% Y:CaF2 crystal under 790 nm diode pumping.

  11. Afterglow properties of CaF{sub 2}:Tm nanoparticles and its potential application in photodynamic therapy

    Energy Technology Data Exchange (ETDEWEB)

    Zahedifar, M., E-mail: zhdfr@kashanu.ac.ir [Physics Department, University of Kashan, Kashan, I.R. Iran (Iran, Islamic Republic of); Institute of Nanoscience and Nanotechniology, University of Kashan, Kashan, I.R. Iran (Iran, Islamic Republic of); Sadeghi, E. [Physics Department, University of Kashan, Kashan, I.R. Iran (Iran, Islamic Republic of); Institute of Nanoscience and Nanotechniology, University of Kashan, Kashan, I.R. Iran (Iran, Islamic Republic of); Shanei, M.M. [Institute of Nanoscience and Nanotechniology, University of Kashan, Kashan, I.R. Iran (Iran, Islamic Republic of); Sazgarnia, A. [Research Center and Department of Medical Physics, School of Medicine, Mashhad University of Medical Sciences, Vakil Abad Blvd., Mashhad (Iran, Islamic Republic of); Mehrabi, M. [Institute of Nanoscience and Nanotechniology, University of Kashan, Kashan, I.R. Iran (Iran, Islamic Republic of)

    2016-03-15

    CaF{sub 2}:Tm nanoparticles (NPs) were synthesized by the hydrothermal method. Intense afterglow emission with long life time was found for the produced NPs, so its applicability in photodynamic therapy was investigated. Since the wavelength of the afterglow emission of the NPs fairly matches with the absorption band of the PpIX sensitizer, especially in the red region, the Cystein mediator was used to bond NPs with the PpIX sensitizer. The CaF{sub 2}:Tm NPs conjugated with PpIX was exposed to X-ray and by using the Antracene as detector, the production of the singlet oxygen was verified. Therefore, the produced NPs are recommended as a source of energy that improves photodynamic therapy beyond its current limitations. - Highlights: • Intense afterglow emission found for the synthesized CaF{sub 2}:Tm nanoparticles. • CaF{sub 2}:Tm emission band fairly matched with PpIX sensitizer's absorption band. • CaF{sub 2}:Tm conjugated with the sensitized is a good candidate for photodynamic therapy. • The application of nanoparticles in producing singlet oxygen was verified.

  12. Study of broadband near-infrared emission in Tm3+-Er3+ codoped TeO2-WO3-PbO glasses.

    Science.gov (United States)

    Balda, R; Fernández, J; Fernández-Navarro, J M

    2009-05-25

    In this work, we report the near-infrared emission properties of Tm(3+)-Er(3+) codoped tellurite TeO(2)-WO(3)-PbO glasses under 794 nm excitation. A broad emission from 1350 to 1750 nm corresponding to the Tm(3+) and Er(3+) emissions is observed. The full width at half-maximum of this broadband increases with increasing [Tm]/[Er] concentration ratio up to a value of ~ 160 nm. The energy transfer between Tm(3+) and Er(3+) ions is evidenced by both the temporal behavior of the near-infrared luminescence and the effect of Tm3+ codoping on the visible upconversion of Er(3+) ions.

  13. 42 CFR 415.152 - Definitions.

    Science.gov (United States)

    2010-10-01

    ... hospital, skilled nursing facility, home health agency, or comprehensive outpatient rehabilitation facility... provisions of § 409.26 or § 409.40(f) for resident services furnished in skilled nursing facilities or home... 42 Public Health 3 2010-10-01 2010-10-01 false Definitions. 415.152 Section 415.152 Public Health...

  14. Color Tunable and Upconversion Luminescence in Yb-Tm Co-Doped Yttrium Phosphate Inverse Opal Photonic Crystals.

    Science.gov (United States)

    Wang, Siqin; Qiu, Jianbei; Wang, Qi; Zhou, Dacheng; Yang, Zhengwen

    2016-04-01

    For this paper, YPO4: Tm, Yb inverse opals with the photonic band gaps at 475 nm and 655 nm were prepared by polystyrene colloidal crystal templates. We investigated the influence of photonic band gaps on the Tm-Yb upconversion emission which was in the YPO4: Tm Yb inverse opal photonic crystals. Comparing with the reference sample, significant suppression of both the blue and red upconversion luminescence of Tm3+ ions were observed in the inverse opals. The color purity of the blue emission was improved in the inverse opal by the suppression of red upconversion emission. Additionally, mechanism of upconversion emission in the inverse opal was discussed. We believe that the present work will be valuable for not only the foundational study of upconversion emission modification but also the development of new optical devices in upconversion lighting and display.

  15. Impact of the Low-Temperature Reactivity of Reillex(TM) HPQ on Actinide Processing

    International Nuclear Information System (INIS)

    Laurinat, J.E.

    2001-01-01

    Reactive System Screening Tool(TM) data and a computational model are used to predict the impact of pressurization on a typical process-scale ion exchange column due to gases generated by a low temperature exothermic reaction (LTE). The LTE results from a reaction between nitric acid and the ethylbenzene pendant groups of the Reillex(TM) HPQ resin. This reaction would occur if the resin bed were inadvertently heated above 70 degrees C

  16. Spaceflight 1.94 Micron Tm Fiber Laser Transmitter, Phase II

    Data.gov (United States)

    National Aeronautics and Space Administration — Fibertek will develop a spaceflight prototype 1940 nm, 100 W thulium (Tm) laser suitable for NASA spaceflight and long-duration unmanned aerial vehicle (UAV)...

  17. Cardiovascular angiography system Infinix{sub TM} CB; Shinzoyo junkanki shindan system Infinix{sub TM} CB

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-03-01

    A cardiovascular angiography system Infinix{sub TM} CB is developed, which is a dedicated system for cardiovascular catheter treatment (intervention), from PTCA (percutaneous transluminal coronary angioplasty) down, capable of two-way biplanar photography. It is designed to be thoroughly operator-friendly, and some of its features are stated below. It is capable of high-speed biplanar positioning at the maximum speed of 10 degrees/second (25% faster than in the conventional type). A side beam vertical motion mechanism is provided rendering biplanar framing faster and easier. Hyper-handling is embodied with ergonomics introduced into the system. (translated by NEDO)

  18. Cardiovascular angiography system Infinix[sub TM] CB. Shinzoyo junkanki shindan system Infinix[sub TM] CB

    Energy Technology Data Exchange (ETDEWEB)

    1999-03-01

    A cardiovascular angiography system Infinix[sub TM] CB is developed, which is a dedicated system for cardiovascular catheter treatment (intervention), from PTCA (percutaneous transluminal coronary angioplasty) down, capable of two-way biplanar photography. It is designed to be thoroughly operator-friendly, and some of its features are stated below. It is capable of high-speed biplanar positioning at the maximum speed of 10 degrees/second (25% faster than in the conventional type). A side beam vertical motion mechanism is provided rendering biplanar framing faster and easier. Hyper-handling is embodied with ergonomics introduced into the system. (translated by NEDO)

  19. Lattice location of Tm in Si and Ge determined from ion channeling followed by Monte Carlo simulations

    International Nuclear Information System (INIS)

    Yamamoto, Y.; Wakaiki, M.; Ikeda, A.; Kido, Y.

    1999-01-01

    The lattice location of Tm implanted into Si(1 0 0) and Ge(1 1 1) with energy of 180 keV was determined precisely by ion channeling followed by Monte Carlo simulations of ion trajectories. The implantations were performed at 550 deg. C with a dose of 5 x 10 14 ions/cm 2 . In the case of Tm in Si, 25 at.% and 50 at.% of Tm are located in the tetrahedral interstitial site and in the random site, respectively and the rest takes the substitutional position. The assumption of the Gaussian distribution centered at the exact tetrahedral site with a standard deviation of 0.2 Angstroms reproduced the azimuth angular-scan spectrum around the [1 1 0] axis. However, the observed angular spectrum is significantly broader than the simulated one. This is probably due to the fact that there exist slightly different Tm lattice sites from the exact tetrahedral position. For Ge(1 1 1) substrates, 25 at.% of Tm occupied the tetrahedral interstitial site and the rest was located randomly

  20. Spaceflight 1.94 micron Tm Fiber Laser Transmitter, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — Fibertek proposes to develop a spaceflight prototype 1940 nm, 100 W thulium (Tm) laser suitable for NASA spaceflight and long-duration unmanned aerial vehicle (UAV)...

  1. Use of the MicroRespTM method to assess pollution-induced community tolerance to metals for lotic biofilms

    International Nuclear Information System (INIS)

    Tlili, Ahmed; Marechal, Marjorie; Montuelle, Bernard; Volat, Bernadette; Dorigo, Ursula; Berard, Annette

    2011-01-01

    Understanding the ecological status of aquatic ecosystems and the impact of anthropogenic contamination requires correlating exposure to toxicants with impact on biological communities. Several tools exist for assessing the ecotoxicity of substances, but there is still a need for new tools that are ecologically relevant and easy to use. We have developed a protocol based on the substrate-induced respiration of a river biofilm community, using the MicroResp TM technique, in a pollution-induced community tolerance approach. The results show that MicroResp TM can be used in bioassays to assess the toxicity toward biofilm communities of a wide range of metals (Cu, Zn, Cd, Ag, Ni, Fe, Co, Al and As). Moreover, a community-level physiological profile based on the mineralization of different carbon substrates was established. Finally, the utility of MicroResp TM was confirmed in an in-situ study showing gradient of tolerance to copper correlated to a contamination gradient of this metal in a small river. - A modified MicroResp TM technique as a tool for measuring induced tolerance to heavy metals of a microbial biofilm community. - Research highlights: → MicroResp TM allows to plot dose-response curves with various tested metals. → Induced-tolerance to copper of heterotrophic biofilm community was successfully measured. → No co-tolerance detected between copper, silver and cadmium by using MicroResp TM . → MicroResp TM allows assessment of change in catabolic diversity in microbial community.

  2. Machine-roomless elevator, SPACEL[sub TM]. Machine roomless elevator SPACEL[sub TM] 'Supesuseru[sub TM]'

    Energy Technology Data Exchange (ETDEWEB)

    1999-03-01

    A machine-roomless elevator, SPACEL[sub TM] requiring no machine room, which operates at a rated speed of 45 and 60 m/min, was put on sale in August 1998 with arrangement for passenger use, residential use and bed use. Another elevator operating at a rated speed of 90 and 105 m/min whose travel distance was extended to 75 m was added to the product series and put on sale in February 1999. The control equipment having been installed in a machine room conventionally was modified to a thickness of 100 mm by adopting an inverter device of thin design and densely mounted substrates. The control equipment was installed on the uppermost floor. The winch is a compact and thin type gearless winch incorporating a permanent magnet synchronizing motor, which was installed at the top of the hoistway. These arrangements have realized a machine-roomless elevator. Further system efficiency improvement has achieved energy conservation of about 10% as compared to the conventional rope type and about 80% as compared to the hydraulic type elevators. (translated by NEDO)

  3. Effect of [Li]/[Nb] ratio on composition and defect structure of Zr:Yb:Tm:LiNbO3 crystals

    Science.gov (United States)

    Liu, Chunrui; Dai, Li; Wang, Luping; Shao, Yu; Yan, Zhehua; Xu, Yuheng

    2018-04-01

    Zr:Yb:Tm:LiNbO3 crystals with various [Li]/[Nb] ratios (0.946, 1.05, 1.20 and 1.38) were grown by the Czochralski technique. Distribution coefficients of Zr4+, Yb3+ and Tm3+ ions were analyzed by the inductively coupled plasma-atomic emission spectrometer (ICP-AES). The influence of [Li]/[Nb] ratio on the composition and defect structure of Zr:Yb:Tm:LiNbO3 crystals was investigated by X-ray diffraction and IR transmission spectrum. The results show that as the [Li]/[Nb] ratio increases in the melt, the distribution coefficients of Yb3+ and Tm3+ ions both increase while that of Zr4+ ion deceases. When the [Li]/[Nb] ratio increases to 1.20 in the melt, Zr:Yb:Tm:LiNbO3 crystal is nearly stoichiometric. In addition, when the [Li]/[Nb] ratio reaches up to 1.38, NbLi4+ are completely replaced and Li+ starts to impel the Zr4+, Yb3+ and Tm3+ into the normal Li sites.

  4. Human TM9SF4 Is a New Gene Down-Regulated by Hypoxia and Involved in Cell Adhesion of Leukemic Cells.

    Directory of Open Access Journals (Sweden)

    Rosa Paolillo

    Full Text Available The transmembrane 9 superfamily protein member 4, TM9SF4, belongs to the TM9SF family of proteins highly conserved through evolution. TM9SF4 homologs, previously identified in many different species, were mainly involved in cellular adhesion, innate immunity and phagocytosis. In human, the function and biological significance of TM9SF4 are currently under investigation. However, TM9SF4 was found overexpressed in human metastatic melanoma and in a small subset of acute myeloid leukemia (AMLs and myelodysplastic syndromes, consistent with an oncogenic function of this gene.In this study, we first analyzed the expression and regulation of TM9SF4 in normal and leukemic cells and identified TM9SF4 as a gene highly expressed in human quiescent CD34+ hematopoietic progenitor cells (HPCs, regulated during monocytic and granulocytic differentiation of HPCs, both lineages giving rise to mature myeloid cells involved in adhesion, phagocytosis and immunity. Then, we found that TM9SF4 is markedly overexpressed in leukemic cells and in AMLs, particularly in M2, M3 and M4 AMLs (i.e., in AMLs characterized by the presence of a more or less differentiated granulocytic progeny, as compared to normal CD34+ HPCs. Proliferation and differentiation of HPCs occurs in hypoxia, a physiological condition in bone marrow, but also a crucial component of cancer microenvironment. Here, we investigated the impact of hypoxia on TM9SF4 expression in leukemic cells and identified TM9SF4 as a direct target of HIF-1α, downregulated in these cells by hypoxia. Then, we found that the hypoxia-mediated downregulation of TM9SF4 expression is associated with a decrease of cell adhesion of leukemic cells to fibronectin, thus demonstrating that human TM9SF4 is a new molecule involved in leukemic cell adhesion.Altogether, our study reports for the first time the expression of TM9SF4 at the level of normal and leukemic hematopoietic cells and its marked expression at the level of AMLs

  5. CO2 laser cladding of VERSAlloyTM on carbon steel with powder feeding

    International Nuclear Information System (INIS)

    Kim, Jae-Do; Kweon, Jin-Wook

    2007-01-01

    Laser cladding processing with metal powder feeding has been experimented on carbon steel with VERSAlloy TM . A special device for the metal powder feeding was designed and manufactured. By adopting proper cladding parameters, good clad layers and sound metallurgical bonding with the base metal were obtained. Analysis indicates that the micro hardness of clad layer and the heat-affected zone increased with increasing of cladding speed. The experimental results showed that VERSAlloy TM cladded well with carbon steel

  6. Theoretical and experimental determination of dosimetric characteristics for brachyseed{sup TM} Pd-103, model Pd-1, source

    Energy Technology Data Exchange (ETDEWEB)

    Meigooni, A.S. E-mail: alimeig@pop.uky.edu; Zhang Hualin; Perry, Candace; Dini, S.A.; Koona, R.A

    2003-05-01

    Dosimetric characteristics of the BrachySeed{sup TM} Pd-103, Model Pd-1 source have been determined using both theoretical and experimental methods. Dose rate constant, radial dose function, and anisotropy functions of the source have been obtained following the TG-43 recommendations. Derivation of the dose rate constant was based on recent NIST WAFAC calibration performed in accordance with their 1999 Standard. Measurements were performed in Solid Water{sup TM} using LiF TLD chips. Theoretical simulation calculations were performed in both Solid Water{sup TM} and water phantom materials using MCNP4C2 Monte Carlo code using DLC-200 interaction data. The results of the Monte Carlo simulation indicated a dose rate constant of 0.65 cGy h{sup -1} U{sup -1} and 0.61 cGy h{sup -1} U{sup -1} in water and Solid Water{sup TM}, respectively. The measured dose rate constant in Solid Water{sup TM} was found to be 0.63{+-}7% cGy h{sup -1} U{sup -1}, which is within the experimental uncertainty of the Monte-Carlo simulated results. The anisotropy functions of the source were calculated in both water and in Solid Water{sup TM} at the radial distances of 1 to 7 cm. Measurements were made in Solid Water{sup TM} at distances of 2, 3, 5, and 7 cm. The Monte-Carlo calculated anisotropy constant of the new source was found to be 0.98 in water. The tabulated data and 5th order polynomial fit coefficients for the radial dose function along with the dose rate constant and anisotropy functions are provided to support clinical use of this source.

  7. The characteristics of CaF2:Tm crystals (TLD-300) irradiated by electromagnetic radiation

    International Nuclear Information System (INIS)

    Ben-Shachar, B.; Yona, S.; Laichter, Y.; German, U.; Weiser, G.

    1985-09-01

    The main characteristics of the CaF 2 :Tm crystals (TLD-300), as a dosimeter, were measured: the glow curve, sensitivity, linearity, fading and energy dependence for photons, and compared to those of LiF (TLD-100) and CaF 2 :Dy (TLD-200). It was found that CaF 2 :Tm can be used for environmental dosimetry by reading the crystals after four days. (Author)

  8. The influence that JavaScript(TM has on the visibility of a Website to search engines - a pilot study

    Directory of Open Access Journals (Sweden)

    M. Weideman

    2006-01-01

    Full Text Available Introduction. In this research project, an empirical pilot study on the relationship between JavaScript(TM usage and Website visibility was carried out. The main purpose was to establish whethe JavaScript(TM-based hyperlinks attract or repel crawlers, resulting in an increase or decrease in Website visibility. Method. A literature survey has established that there appears to be contradiction amongst claims by various authors as to whether or not crawlers can parse or interpret JavaScript(TM. The chosen methodology involved the creation of a Website that contains different kinds of links to other pages, where actual data files were stored. Search engine crawler visits to the page pointed to by the different kinds of links were monitored and recorded. Analysis. This experiment took into account the fact that JavaScript(TM can be embedded within the HTML of a Web page or referenced as an external '.js' file. It also considered different ways of specifying links within JavaScript(TM. Results. The results obtained indicated that text links provide the highest level of opportunity for crawlers to discover and index non-homepages. In general, crawlers did not follow Javascript(TM-based links to Web pages blindly. Conclusion. . Most crawlers evade Javascript(TM links, implying that Web pages using forms of this technology, for example in pop-up/pull-down menus, could be jeopardising their chances of achieving high search engine rankings. Certain Javascript(TM links were not followed at all, which has serious implications for designers of e-Commerce Websites.

  9. Crystal fields in Sc, Y, and the heavy-rare-earth metals Tb, Dy, Ho, Er, Tm, and Lu

    International Nuclear Information System (INIS)

    Touborg, P.

    1977-01-01

    Experimental investigations of the magnetic poperties of dilute alloys of the rare-earth solutes Tb, Dy, Ho, Er, and Tm in the nonmagnetic hosts Lu, Y, and Sc have been performed. These measurements, which include and supplement earlier published results, have been analyzed and crystal-field parameters for all these 15 alloy systems deduced. The consistency of the parameters was confirmed by a variety of magnetic measurements, including neutron spectroscopy. Crystal-field parameters have also been derived for the ions in pure magnetic rare-earth metals and their alloys using the results for the dilute alloys supplemented with paramagnetic measurements up to high temperatures on the concentrated systems. Mean values and standard deviations of the higher-order crystal-field parameters for all Y and Lu alloys are B 40 /β = 6.8 +- 0.9 K, B 60 /γ = 13.6 +- 0.7 K, and B 66 /γ = (9.7 +- 1.1) B 60 /γ. These values: with the inaccuracies somewhat increased: are expected to be representative also for the magnetic rare-earth metals. For rare-earth ions in the Sc host the values B 40 /β = 9.9 +- 1.9 K, B 60 /γ = 19.8 +- 1.5 K, and B 66 /γ = (9.4 +- 0.9) B 60 /γ were deduced. B 20 /α is a host-sensitive parameter which has the average values of -102.7, -53.4, and 29.5 K for rare-earth ions in Y, Lu, and Sc, respectively. There is also evidence that this parameter varies with the solute. B 20 /α for ions in the pure magnetic rare-earth metals and their alloys shows a linear variation with c/a ratio characteristic of each ion. The results indicate a contribution from anisotropic exchange to the high-temperature paramagnetic anisotropy of approximately 20% for Tb, Dy, Ho, and Er, and approximately 10% for Tm

  10. Effects of Lu and Tm Doping on Thermoelectric Properties of Bi2Te3 Compound

    Science.gov (United States)

    Yaprintsev, Maxim; Lyubushkin, Roman; Soklakova, Oxana; Ivanov, Oleg

    2018-02-01

    The Bi2Te3, Bi1.9Lu0.1Te3 and Bi1.9Tm0.1Te3 thermoelectrics of n-type conductivity have been prepared by the microwave-solvothermal method and spark plasma sintering. These compounds behave as degenerate semiconductors from room temperature up to temperature T d ≈ 470 K. Within this temperature range the temperature behavior of the specific electrical resistivity is due to the temperature changes of electron mobility determined by acoustic and optical phonon scattering. Above T d, an onset of intrinsic conductivity takes place when electrons and holes are present. At the Lu and Tm doping, the Seebeck coefficient increases, while the specific electrical resistivity and total thermal conductivity decrease within the temperature 290-630 K range. The increase of the electrical resistivity is related to the increase of electron concentration since the Tm and Lu atoms are donor centres in the Bi2Te3 lattice. The increase of the density-of-state effective mass for conduction band can be responsible for the increase of the Seebeck coefficient. The decrease of the total thermal conductivity in doped Bi2Te3 is attributed to point defects like the antisite defects and Lu or Tm atoms substituting for the Bi sites. In addition, reducing the electron thermal conductivity due to forming a narrow impurity (Lu or Tm) band having high and sharp density-of-states near the Fermi level can effectively decrease the total thermal conductivity. The thermoelectric figure-of-merit is enhanced from ˜ 0.4 for undoped Bi2Te3 up to ˜ 0.7 for Bi1.9Tm0.1Te3 and ˜ 0.9 for Bi1.9Lu0.1Te3.

  11. Experiences with OpenMP in tmLQCD

    Energy Technology Data Exchange (ETDEWEB)

    Deuzeman, A. [Bern Univ. (Switzerland). Albert Einstein Center for Fundamental Physics; Jansen, K. [Deutsches Elektronen-Synchrotron (DESY), Zeuthen (Germany). John von Neumann-Inst. fuer Computing NIC; Kostrzewa, B. [Humboldt Univ. Berlin (Germany). Inst. fuer Physik; Deutsches Elektronen-Synchrotron (DESY), Zeuthen (Germany). John von Neumann-Inst. fuer Computing NIC; Urbach, C. [Bonn Univ. (Germany). HISKP (Theory); Collaboration: European Twisted Mass Collaboration

    2013-11-15

    An overview is given of the lessons learned from the introduction of multi-threading using OpenMP in tmLQCD. In particular, programming style, performance measurements, cache misses, scaling, thread distribution for hybrid codes, race conditions, the overlapping of communication and computation and the measurement and reduction of certain overheads are discussed. Performance measurements and sampling profiles are given for different implementations of the hopping matrix computational kernel.

  12. Experiences with OpenMP in tmLQCD

    International Nuclear Information System (INIS)

    Deuzeman, A.

    2013-11-01

    An overview is given of the lessons learned from the introduction of multi-threading using OpenMP in tmLQCD. In particular, programming style, performance measurements, cache misses, scaling, thread distribution for hybrid codes, race conditions, the overlapping of communication and computation and the measurement and reduction of certain overheads are discussed. Performance measurements and sampling profiles are given for different implementations of the hopping matrix computational kernel.

  13. Commercialization of Medium Voltage HTS Triax TM Cable Systems

    Energy Technology Data Exchange (ETDEWEB)

    Knoll, David

    2012-12-31

    The original project scope that was established in 2007 aimed to install a 1,700 meter (1.1 mile) medium voltage HTS Triax{TM} cable system into the utility grid in New Orleans, LA. In 2010, however, the utility partner withdrew from the project, so the 1,700 meter cable installation was cancelled and the scope of work was reduced. The work then concentrated on the specific barriers to commercialization of HTS cable technology. The modified scope included long-length HTS cable design and testing, high voltage factory test development, optimized cooling system development, and HTS cable life-cycle analysis. In 2012, Southwire again analyzed the market for HTS cables and deemed the near term market acceptance to be low. The scope of work was further reduced to the completion of tasks already started and to testing of the existing HTS cable system in Columbus, OH. The work completed under the project included: • Long-length cable modeling and analysis • HTS wire evaluation and testing • Cable testing for AC losses • Optimized cooling system design • Life cycle testing of the HTS cable in Columbus, OH • Project management. The 200 meter long HTS Triax{TM} cable in Columbus, OH was incorporated into the project under the initial scope changes as a test bed for life cycle testing as well as the site for an optimized HTS cable cooling system. The Columbus cable utilizes the HTS TriaxTM design, so it provided an economical tool for these of the project tasks.

  14. Electronic structure of Pd42.5Ni7.5Cu30P20, an excellent bulk metallic glass former: Comparison to the Pd40Ni40P20 reference glass

    International Nuclear Information System (INIS)

    Hosokawa, S.; Sato, H.; Happo, N.; Mimura, K.; Tezuka, Y.; Ichitsubo, T.; Matsubara, E.; Nishiyama, N.

    2007-01-01

    In-house photoemission and inverse-photoemission spectra (PES and IPES) were measured on Pd 42.5 Ni 7.5 Cu 30 P 20 and Pd 40 Ni 40 P 20 bulk metallic glasses in order to clarify the origin of excellent glass-forming ability from the viewpoint of electronic structure. Minima are observed for both the metallic glasses at a slightly higher energy than the Fermi level. Incident photon-energy dependent PES spectra were obtained using synchrotron radiation and the Pd 4d partial density of states (DOS) was estimated from the PES data. Soft X-ray emission spectra were also measured near the Ni and Cu 2p 3/2 absorption edges to evaluate, respectively, the Ni and Cu 3d partial DOS in the valence band. The Pd 4d and the Ni and Cu 3d partials in the conduction band were obtained from X-ray absorption spectra around the Pd 3p 3/2 and Ni and Cu 2p 3/2 absorption edges, respectively. It was found that the Pd 4d partial DOS near the Fermi energy largely decreases and becomes localized by replacing the Ni atoms with the Cu atoms, which may be closely related to the excellent glass-forming ability of the Pd 42.5 Ni 7.5 Cu 30 P 20 bulk metallic glass due to a selective formation of Pd-P covalent bonds

  15. Rare Functional Variant in TM2D3 is Associated with Late-Onset Alzheimer's Disease.

    Directory of Open Access Journals (Sweden)

    Johanna Jakobsdottir

    2016-10-01

    Full Text Available We performed an exome-wide association analysis in 1393 late-onset Alzheimer's disease (LOAD cases and 8141 controls from the CHARGE consortium. We found that a rare variant (P155L in TM2D3 was enriched in Icelanders (~0.5% versus <0.05% in other European populations. In 433 LOAD cases and 3903 controls from the Icelandic AGES sub-study, P155L was associated with increased risk and earlier onset of LOAD [odds ratio (95% CI = 7.5 (3.5-15.9, p = 6.6x10-9]. Mutation in the Drosophila TM2D3 homolog, almondex, causes a phenotype similar to loss of Notch/Presenilin signaling. Human TM2D3 is capable of rescuing these phenotypes, but this activity is abolished by P155L, establishing it as a functionally damaging allele. Our results establish a rare TM2D3 variant in association with LOAD susceptibility, and together with prior work suggests possible links to the β-amyloid cascade.

  16. Short-Term Safety and Efficacy of Femoral Vascular Closure after Percutaneous Coronary Intervention with Combination of the Boomerang(TM) Device and Intravenous Protamine Sulfate.

    Science.gov (United States)

    Chen, Ching-Pei; Huang, Huang-Kai; Hsia, Chien-Hsun; Chang, Yung-Ming; Lin, Lee-Shin; Lee, Cheng-Liang

    2013-11-01

    The Cardiva Boomerang(TM) is a device used to perform femoral vascular closure. It facilitates passive hemostasis at the arteriotomy site, leaving no residual foreign body. We performed a controlled, randomized study of 60 patients undergoing percutaneous coronary intervention. Patients were randomized into two groups (30 per group) to undergo vascular closure with the Boomerang(TM) or the Perclose(TM) suture-based device after the intravenous administration of protamine sulfate. We compared overall success rates, patient-reported pain, length of time to achieve hemostasis and mobilization of the patient, and the frequency of complications in the two groups. Overall success rates using the Boomerang(TM) and Perclose(TM) devices were similarly high, at 93% and 97%, respectively. The Boomerang(TM) was significantly quicker to deploy than the PercloseTM, device deployment time, median (Q1-Q3), [2.00 (1.33-2.75) vs. 3.84 (2.75-4.38) mins, p Boomerang(TM) group (1.1 ± 1.7 vs. 6.4 ± 2.9, p Boomerang(TM) (p Boomerang(TM) device is as safe and effective as the Perclose(TM) device for femoral vascular closure, but quicker to deploy and less painful to patients. Boomerang; Percutaneous intervention; Vascular closure device.

  17. Laser-induced, Er3+ trace-sensitized red-to-blue photon avalanche up-conversion in Tm3+-doped LiKYF5 crystals

    International Nuclear Information System (INIS)

    Jouart, J P; Bouffard, M; Boulma, E; Diaf, M; Vojtenko, E N; Khaidukov, N M

    2005-01-01

    The results for a spectroscopic study demonstrating that the excited-state absorption(ESA) of Tm 3+ :LiKYF 5 at 648nm is dependent on the purity of starting materials used for synthesizing the crystal are presented. The Er 3+ -free LiKYF 5 crystal doped with Tm 3+ is transparent at 648 nm because the majority of the Tm 3+ ions are in the ground 3 H 6 state whatever the selective excitation intensity, whereas the Er 3+ -contaminated crystal is semi-transparent. In the second case a small increase of the excitation intensity above a certain threshold produces an abrupt enhancement of the ESA process at 648 nm as well as the blue and the green emissions that are detected. All three processes, namely ESA corresponding to the 3 F 4 (2) → 1 G 4 (2) Tm 3+ transition, the blue emission due to the 1 G 4 → 3 H 6 Tm 3+ transition and the green emission from the 4 S 3/2 Er 3+ level, are sensitized with the Tm 3+ → Er 3+ → Tm 3+ energy transfers which promote the conversion of Tm 3+ ions from the 1 G 4 and the 3 H 4 states to the metastable 3 F 4 state

  18. DVD. Piret Tamm soovitab : "Rütm kisub kaasa" / Piret Tamm

    Index Scriptorium Estoniae

    Tamm, Piret, 1966-

    2007-01-01

    Mängufilm "Rütm kisub kaasa" ("Take the Lead") : režissöör Liz Friedlander : peaosas Antonio Banderas : Ameerika Ühendriigid 2006. Film põhineb tantsuõpetaja Pierre Dulaine'i tantsuteraapia tegevusel

  19. Crystalline phase, profile characteristics and spectroscopic properties of Er3+/Tm3+-diffusion-codoped LiNbO3 crystal

    International Nuclear Information System (INIS)

    Sun, Wen-Bao; Zhang, Zi-Bo; Sun, Hong-Xue; Wong, Wing-Han; Yu, Dao-Yin; Pun, Edwin Yue-Bun

    2017-01-01

    Er 3+ /Tm 3+ -codoped LiNbO 3 crystal was prepared by co-diffusion of stacked Er and Tm metal films coated onto surface of off-congruent, Li-deficient LiNbO 3 substrate produced by Li-poor vapor transport equilibration technique. The crystalline phase on the diffused surface was analyzed by X-ray single-crystal diffraction. The Er 3+ and Tm 3+ profile characteristics were studied by secondary ion mass spectrometry. The emission spectra were measured under the 980 or 795 nm wavelength excitation, and the emission and absorption cross section spectra were calculated based upon McCumber theory. The lifetimes of some emissions were measured. The results show that the Er 3+ and Tm 3+ ions presence is in the form of LiNbO 3 phase. Both ions obey to Gaussian profile with a diffusion depth 21.5 μm. In the codoping case, both ions keep their respective spectroscopic features of only doping case and do not affect each other. The codoping enables to combine the wavelength emissions of both ions and the resultant emission band in the telecommunication window around 1.5 μm is as wide as 150 nm, providing the possibility of S+C+L broadband amplification by employing commercial 980 and 795 nm laser diodes as the pump sources. The Er 3+ /Tm 3+ -codoped LN is a promising host material for integrated optics. - Graphical abstract: Er 3+ /Tm 3+ -codoped LiNbO 3 crystal was prepared by co-diffusion of stacked Er and Tm metal films. The crystalline phase, diffusion profile and cross section spectra of Er 3+ and Tm 3+ ions in the diffusion layer have been investigated. The results show that the presence of Er 3+ and Tm 3+ ions is in the LiNbO 3 phase. Both ions follow Gaussian profile with a diffusion depth 21.5 μm. Both ions keep their respective spectroscopic features of only doping case. Excited state absorption is the dominant process for 795-nm-upconvered fluorescence of Tm 3+ . The codoping enables to combine the wavelength emissions of both ions and provide the possibility of S

  20. Ceratoplastia endotelial com desnudamento da Descemet(DSEK utilizando o dispositivo TAN EndoGlideTM: série de casos

    Directory of Open Access Journals (Sweden)

    Henrique Santiago Baltar Pazos

    2011-06-01

    Full Text Available OBJETIVO: Relatar os resultados da ceratoplastia endotelial com desnudamento da Descemet (DSEK utilizando o dispositivo TAN EndoGlideTM para facilitar a introdução da membrana endotelial. MÉTODOS: Série de casos consecutivos, prospectiva. Foram incluídos 9 pacientes com edema corneano secundário à disfunção endotelial. Melhor acuidade visual corrigida, refração, astigmatismo ceratométrico, espessura corneana central, densidade das células endoteliais e complicações foram analisadas após seguimento de seis meses. RESULTADOS: Houve melhora do edema de córnea e da visão em 7 pacientes (77,78%. A melhor acuidade visual corrigida ficou entre 20/40 e 20/200. A densidade endotelial média após 6 meses variou entre 1.305 céls/mm² e 2.346 céls/mm² com média de perda de 33,14%. Desprendimento de parte do enxerto ocorreu em 1 olho (11,11%, falência primária do transplante endotelial em 2 olhos (22,22%. CONCLUSÃO: O dispositivo TAN EndoGlideTM facilita a introdução do enxerto na ceratoplastia endotelial com desnudamento da Descemet.

  1. Computer image of the new Building 42

    CERN Multimedia

    2008-01-01

    The new Building 42, a new extension to building 40, will make extra space for physicists working on the LHC experiments. The project, which is managed by the TS Civil Engineering Group, will be finished in autumn 2010.

  2. Iranian 42/40 inch gas line to central Persia and USSR one of the world's largest

    Energy Technology Data Exchange (ETDEWEB)

    Naghavi, S; Manoochehri, N

    1969-03-01

    Iran Gas Trunkline consists of 1,120 km of 42 in./40 in. main pipeline, and 675 km of spur lines. It also consists of 104 km gas gathering lines, compression facilities for collection, treatment, and transportation of dry sweet gas to Shiraz, Esfahan and Tehran for industrial purposes in early spring 1970 and export gas to Russia during fall that year. The system will have an ultimate capacity for 1,650 MMscfd of gas equivalent to about 275,000 bpd of crude oil. Distribution will commence in Tehran and Esfahan in 1970, probably to industrial consumers only initially, but later on also to domestic and commercial users. Gas will be used extensively for power generation in these cities, the need for which is increasing rapidly. The source gas used in this pipeline would otherwise be flared to waste.

  3. Integrated Cu-based TM-pass polarizer using CMOS technology platform

    KAUST Repository

    Ng, Tien Khee; Khan, Mohammed Zahed Mustafa; Ooi, Boon S.

    2010-01-01

    A transverse-magnetic-pass (TM-pass) copper (Cu) polarizer is proposed and analyzed using the previously published two-dimensional Method-of-Lines beam-propagation model. The proposed polarizer exhibits a simulated high-pass filter characteristics

  4. Spectroscopic properties of 1.8 μm emission in Tm3+ doped bismuth silicate glass

    International Nuclear Information System (INIS)

    Zhao, Guoying; Tian, Ying; Wang, Xin; Fan, Huiyan; Hu, Lili

    2013-01-01

    The emission properties around 1.8 μm in Tm 3+ doped bismuth silicate glass have been investigated. Based on the obtained Raman spectroscopy and differential scanning calorimetry curves, it is found the introduced Bi 2 O 3 can efficiently reduce the phonon energy of silicate glass to 926 cm −1 . The energy gap between glass transition temperature and onset temperature of crystallization is 169 °C. The OH − content maintains lower in glass by bubbling dry O 2 during the melting process. The cut-off wavelength in mid-infrared range is as long as 5 μm. Bismuth silicate glass has high radiative transition probability of 238.80 s −1 corresponding to the Tm 3+ : 3 F 4 → 3 H 6 transition compared with conventional silicate glasses. The strongest emission at 1.8 μm with a large full width at half-maximum of 238 nm is achieved from this bismuth silicate glass doped with 0.9 mol% Tm 2 O 3 . Its fluorescence lifetime at 1.8 μm is 640 μs. - Highlights: ► The 1.8 μm fluorescence of Tm 3+ -doped bismuth silicate glass is investigated. ► The prepared glass has lower phonon energy than other typical silicate glasses. ► A broadband 1.8 μm emission with the FWHM of 238 nm is observed. ► The fluorescence lifetime of Tm 3+ : 3 F 4 level reaches 640 μs.

  5. Evaluation of Petrifilms(TM) as a diagnostic test to detect bovine mastitis organisms in Kenya.

    Science.gov (United States)

    Gitau, George K; Bundi, Royford M; Vanleeuwen, John; Mulei, Charles M

    2013-03-01

    The study purpose was to validate Petrifilms(TM) (3M Microbiology, 2005) against standard culture methods in the diagnosis of bovine mastitis organisms in Kenya. On 128 smallholder dairy cattle farms in Kenya, between June 21, 2010 and August 31, 2010, milk samples from 269 cows that were positive on California Mastitis Test (CMT) were cultured using standard laboratory culture methods and Petrifilms(TM) (Aerobic Count and Coliform Count -3M Microbiology, 2005), and results were compared. Staphylococcus aureus was the most common bacterium isolated (73 % of samples). Clinical mastitis was found in only three cows, and there were only two Gram-negative isolates, making it impossible to examine the agreement between the two tests for Gram-negative- or clinical mastitis samples. The observed agreement between the standard culture and Petrifilm(TM) (3M Microbiology, 2005) results for Gram-positive isolates was 85 %, and there was fair agreement beyond that expected due to chance alone, with a kappa (κ) of 0.38. Using culture results as a gold standard, the Petrifilms(TM) had a sensitivity of 90 % for Gram-positive samples and specificity of 51 %. With 87 % of CMT-positive samples resulting in Gram-positive pathogens cultured, there was a positive predictive value of 93 % and a negative predictive value of 43 %. Petrifilms(TM) should be considered for culture of mastitis organisms in developing countries, especially when Gram-positive bacteria are expected.

  6. TM6SF2 and MAC30, new enzyme homologues in sterol metabolism and common metabolic disease.

    Directory of Open Access Journals (Sweden)

    Luis eSanchez-Pulido

    2014-12-01

    Full Text Available Carriers of the Glu167Lys coding variant in the TM6SF2 gene have recently been identified as being more susceptible to non-alcoholic fatty liver disease (NAFLD, yet exhibit lower levels of circulating lipids and hence are protected against cardiovascular disease. Despite the physiological importance of these observations, the molecular function of TM6SF2 remains unknown, and no sequence similarity with functionally characterised proteins has been identified. In order to trace its evolutionary history and to identify functional domains, we embarked on a computational protein sequence analysis of TM6SF2. We identified a new domain, the EXPERA domain, which is conserved among TM6SF, MAC30/TMEM97 and EBP (D8,D7 sterol isomerase protein families. EBP mutations are the cause of chondrodysplasia punctata 2 X-linked dominant (CDPX2, also known as Conradi-Hünermann-Happle syndrome, a defective cholesterol biosynthesis disorder. Our analysis of evolutionary conservation among EXPERA domain-containing families and the previously suggested catalytic mechanism for the EBP enzyme, indicate that TM6SF and MAC30/TMEM97 families are both highly likely to possess, as for the EBP family, catalytic activity as sterol isomerases. This unexpected prediction of enzymatic functions for TM6SF and MAC30/TMEM97 is important because it now permits detailed experiments to investigate the function of these key proteins in various human pathologies, from cardiovascular disease to cancer.

  7. Analysis of Golf Swing Motion and Applied Loads on the Human Body Using Soft-Golf TM Club

    International Nuclear Information System (INIS)

    Kwak, Ki Young; So, Ha Ju; Kim, Sung Hyeon; Kim, Dong Wook; Kim, Nam Gyun

    2011-01-01

    The purpose of this study was to analyze the kinetic effect of Soft-golf TM instrument on the human body structure. To analyze the kinetic effect of Soft-golf TM instrument, Golf swing using Soft-golf TM instrument and regular golf instrument was captured. And then Upper limbs and lumbar joint torques was calculated via computer simulation. Five man participated this study. Subjects performed golf swing using a regular golf and Soft-golf TM instrument. Golf swing motion was captured using three position sensor, active infrared LED maker and force plate. Golf swing model was generated and simulated using ADAMS/LifeMOD program. As a results, joint torque during Soft-golf swing were lower than regular golf swing. Thus soft-golf swing have joint load lower than regular golf swing and contribute to reduce joint injury

  8. Self-mode-locking operation of a diode-end-pumped Tm:YAP laser with watt-level output power

    Science.gov (United States)

    Zhang, Su; Zhang, Xinlu; Huang, Jinjer; Wang, Tianhan; Dai, Junfeng; Dong, Guangzong

    2018-03-01

    We report on a high power continuous wave (CW) self-mode-locked Tm:YAP laser pumped by a 792 nm laser diode. Without any additional mode-locking elements in the cavity, stable and self-starting mode-locking operation has been realized. The threshold pump power of the CW self-mode-locked Tm:YAP laser is only 5.4 W. The maximum average output power is as high as 1.65 W at the pump power of 12 W, with the repetition frequency of 468 MHz and the center wavelength of 1943 nm. To the best of our knowledge, this is the first CW self-mode-locked Tm:YAP laser. The experiment results show that the Tm:YAP crystal is a promising gain medium for realizing the high power self-mode-locking operation at 2 µm.

  9. Single-phased CaAl2Si2O8:Tm3+, Dy3+ white-light phosphors under ultraviolet excitation

    International Nuclear Information System (INIS)

    Yang, Penghui; Yu, Xue; Xu, Xuhui; Jiang, Tingming; Yu, Hongling; Zhou, Dacheng; Yang, Zhengwen; Song, Zhiguo; Qiu, Jianbei

    2013-01-01

    A novel white-light-emitting phosphor CaAl 2 Si 2 O 8 :Tm, Dy was synthesized in ambient atmosphere by solid-state reaction. The energy transfer from Tm 3+ to Dy 3+ ions via a dipole–quadrupole reaction was observed and investigated. Upon UV excitation, white light emission was achieved by integrating a blue emission band located at 455 nm and an orange one located at 574 nm attributed to Tm 3+ and Dy 3+ ions, respectively. In addition, the energy-transfer efficiency and critical distance were calculated. Results suggested that the phosphor might be promising as a single-phased white-light-emitting phosphor for UV white-light LED. - Graphical abstract: The results indicate the existence of energy transfer from Tm 3+ to Dy 3+ . By tuning the concentration of Dy 3+ , single-phased white light can be realized. - Highlights: ► Energy transfer from Tm 3+ to Dy 3+ was investigated. ► Color tunable from blue to white can be achieved. ► White light can be realized in CaAl 2 Si 2 O 8 :Tm 3+ , Dy 3+ phosphor

  10. Tm2+ luminescent materials for solar radiation conversion devices

    NARCIS (Netherlands)

    Van der Kolk, E.

    2015-01-01

    A solar radiation conversion device is described that comprises a luminescent Tm 2+ inorganic material for converting solar radiation of at least part of the UV and/or visible and/or infra red solar spectrum into infrared solar radiation, preferably said infrared solar radiation having a wavelength

  11. Tilted axis rotation in odd-odd {sup 164}Tm

    Energy Technology Data Exchange (ETDEWEB)

    Reviol, W.; Riedinger, L.L.; Wang, X.Z.; Zhang, J.Y. [Univ. of Tennessee, Knoxville, TN (United States)] [and others

    1996-12-31

    Ten band structures are observed in {sup 164}Tm, among them sets of parallel and anti-parallel couplings of the proton and neutron spins. The Tilted Axis Cranking scheme is applied for the first time to an odd-odd nucleus in a prominent region of nuclear deformation.

  12. Development of the Taiwanese Mandarin Main Concept Analysis (TM-MCA: Normative and Preliminary Aphasic Data

    Directory of Open Access Journals (Sweden)

    Anthony Pak Hin Kong

    2014-03-01

    Full Text Available Introduction Compared to the English literature, there is a great paucity of studies focusing on quantitative analysis of aphasic oral discourse in Chinese, especially for native speakers of Taiwanese-Mandarin residing in Taiwan. Several studies that investigated deficits of aphasic discourse have been conducted in Cantonese Chinese, including the Cantonese Linguistic Communication Measure (CLCM, Kong & Law, 2004, Main Concept Analysis (MCA; Kong, 2009, and Cantonese version of the Quantitative Production Analysis (Law, 2001; Yiu & Worrall, 1996. Clinical or research application of these systems to the Taiwanese population is limited by the differences of phonology, semantics, and grammar between Taiwanese Mandarin and Cantonese. The current study, therefore, aimed to develop a culturally appropriate Taiwan Mandarin Main Concept Analysis (TM-MCA, by translating and adapting the MCA in Cantonese (Kong, 2009, 2011, and then to validate the tool on the basis of normal speakers and people with aphasia in Taiwan. Method Picture stimuli and main concepts for the TM-MCA: Eight certified Taiwanese SLPs participated and listed all main concepts upon presentation of the sequential pictures in Kong (2009. A main concept referred to a statement consisting of only one main verb with two or more pieces of essential information accurately related to the pictures and informative about the content. All main concepts mentioned by six out of eight SLPs were included in a preliminary main concept list. Further validation of the list involved recruiting eight normal speakers to orally describe the same picture sets. Only those scored as Accurate and Complete (AC or Accurate but Incomplete (AI by at least five speakers were put in the final list. Normative and aphasic data collection and analysis: Thirty six native Taiwanese Mandarin speakers and ten individuals with aphasia orally perform the same picture description tasks. Six measures, including Number of Accurate

  13. Assessment of dynamic softening mechanisms in Allvac 718Plus{sup TM} by EBSD analysis

    Energy Technology Data Exchange (ETDEWEB)

    Mitsche, Stefan, E-mail: stefan.mitsche@felmi-zfe.at [Institute for Electron Microscopy, Graz University of Technology, Steyrergasse 17, Graz (Austria); Sommitsch, Christof [Institute for Material Science and Welding, Christian Doppler Laboratory for Materials Modelling and Simulation, Graz University of Technology, Graz (Austria); Huber, Daniel; Stockinger, Martin [Boehler Schmiedetechnik GmbH and Co KG, Kapfenberg (Austria); Poelt, Peter [Institute for Electron Microscopy, Graz University of Technology, Steyrergasse 17, Graz (Austria)

    2011-04-25

    Research highlights: {yields} EBSD investigations of hot deformed superalloy Allvac 718Plus{sup TM}. {yields} Dynamic softening (recovery, DDRX and CDRX) in dependence on the temperature and strain rate. {yields} At high temperature (1050 deg. C) and high strain rate (10 s{sup -1}) mainly DDRX. {yields} At high temperature (1050 deg. C) and low strain rate (0.1 s{sup -1}) combination of DDRX, CDRX and recovery. - Abstract: The nickel-based superalloy Allvac 718Plus{sup TM} is a future candidate for turbine disc applications, as this new material combines the formability and cost advantages of Alloy 718 with the higher temperature capability of Waspaloy. Due to the strong influence of the microstructure on the final mechanical properties, a fundamental knowledge of the dynamic recrystallization mechanism of Allvac 718Plus{sup TM} is of great importance in order to develop precise microstructure evolution models for this material. Compression tests were performed at temperatures of 900 deg. C to 1050 deg. C and strain rates between 0.1 s{sup -1} and 10 s{sup -1}. The microstructures obtained were analyzed by electron backscatter diffraction (EBSD) to evaluate the influence of the different hot forming parameters on the dynamic softening processes of Allvac 718Plus{sup TM}.

  14. VUV spectroscopy of Tm3+ and Mn2+ doped LiSrAlF6

    International Nuclear Information System (INIS)

    True, M.; Kirm, M.; Negodine, E.; Vielhauer, S.; Zimmerer, G.

    2004-01-01

    LiSrAlF 6 (LiSAF) crystals doped with either Tm 3+ or Mn 2+ were obtained by solid-state reaction and investigated spectroscopically using synchrotron radiation in the vacuum-ultra-violet and ultra-violet spectral regions. In the Tm 3+ doped LiSAF crystals, the slow spin-forbidden 5d-4f emission peaking at 166 nm with a lifetime of at least 1 μs was observed. The respective excitation spectrum consists of several bands in the range of 160-110 nm arising due to the 4f-5d absorption. The f-f emissions of Tm 3+ are well excited in the range of 135-110 nm, but not under excitation into the lower lying d-bands. The excitation mechanisms of different emissions will be discussed including the F - to Tm 3+ charge transfer excitation peaking at 127 nm in LiSAF. The characteristic broad 4 T 1 → 6 A 1 emission band of Mn 2+ peaking at 508 (504) nm was observed in LiSAF:Mn 2+ crystal at 10 (300) K. Three intense excitation bands, tentatively ascribed to the 3d-4s transitions of Mn 2+ , were revealed in the range of 170-110 nm

  15. Using Interdisciplinary Research Methods to Revise and Strengthen the NWS TsunamiReadyTM Community Recognition Program

    Science.gov (United States)

    Scott, C.; Gregg, C. E.; Ritchie, L.; Stephen, M.; Farnham, C.; Fraser, S. A.; Gill, D.; Horan, J.; Houghton, B. F.; Johnson, V.; Johnston, D.

    2013-12-01

    The National Tsunami Hazard Mitigation Program (NTHMP) partnered with the National Weather Service (NWS) in early 2000 to create the TsunamiReadyTM Community Recognition program. TsunamiReadyTM, modeled after the older NWS StormReadyTM program, is designed to help cities, towns, counties, universities and other large sites in coastal areas reduce the potential for disastrous tsunami-related consequences. To achieve TsunamiReadyTM recognition, communities must meet certain criteria aimed at better preparing a community for tsunami, including specific actions within the following categories: communications and coordination, tsunami warning reception, local warning dissemination, community preparedness, and administration. Using multidisciplinary research methods and strategies from Public Health; Psychology; Political, Social and Physical Sciences and Evaluation, our research team is working directly with a purposive sample of community stakeholders in collaboration and feedback focus group sessions. Invitation to participate is based on a variety of factors including but not limited to an individual's role as a formal or informal community leader (e.g., in business, government, civic organizations), or their organization or agency affiliation to emergency management and response. Community organizing and qualitative research methods are being used to elicit discussion regarding TsunamiReadyTM requirements and the division of requirements based on some aspect of tsunami hazard, vulnerability and risk, such as proximity to active or passive plate margins or subduction zone generated tsunamis versus earthquake-landslide generated tsunamis . The primary aim of this research is to use social science to revise and refine the NWS TsunamiReadyTM Guidelines in an effort to better prepare communities to reduce risk to tsunamis.

  16. Overmoded subterahertz surface wave oscillator with pure TM01 mode output

    International Nuclear Information System (INIS)

    Wang, Guangqiang; Zeng, Peng; Wang, Dongyang; Wang, Jianguo; Li, Shuang

    2016-01-01

    Overmoded O-type Cerenkov generators using annular electron beams are facing the problem of multi-modes output due to the inevitable structural discontinuities. A simple but effective method to achieve the pure TM 01 mode output is applied on the 0.14 THz overmoded surface wave oscillator (SWO) in this paper. In spite of still using an overmoded slow wave structure to ensure the easy fabrication, the followed smooth circular waveguide is shrinkingly tapered to the output waveguide with appropriate radius that it cuts off other higher modes except TM 01 mode. Moreover, the modified device here has the same power capacity as the previous one according to the numerical analysis. By optimized lengths of the transition waveguide and tapered waveguide, particle-in-cell simulation results indicate that the subterahertz wave with output power increased 14.2% at the same frequency is obtained from the proposed SWO under the previous input conditions, and importantly, the output power is all carried by TM 01 mode as expected. Further simulation results in the pulse regime confirm the feasibility of the optimized structure in the actual experiments. This simple and viable design is also applicable to overmoded devices in the lower frequency band of subterahertz wave

  17. A novel high color purity blue-emitting phosphor: CaBi{sub 2}B{sub 2}O{sub 7}:Tm{sup 3+}

    Energy Technology Data Exchange (ETDEWEB)

    Li, Jiangong, E-mail: lijiangong01@gmail.com [Department of Electronic Science and Engineering, Huanghuai University, Zhumadian 463000 (China); Yan, Huifang [Department of Foreign Languages and Literature, Huanghuai University, Zhumadian 463000 (China); Yan, Fengmei [Department of Chemistry and Chemical Engineering, Huanghuai University, Zhumadian 463000 (China)

    2016-07-15

    Graphical abstract: - Highlights: • A series of Tm{sup 3+}-doped CaBi{sub 2}B{sub 2}O{sub 7} blue-emitting phosphors were prepared. • The optimum doping content of Tm{sup 3+} ions was found. • The critical distance and concentration quenching mechanism was discussed. • The color purity of as prepared sample was analyzed and compared. - Abstract: A series of Tm{sup 3+}-doped CaBi{sub 2−x}B{sub 2}O{sub 7}:xTm{sup 3+} (0.02 ≤ x ≤ 0.12) blue-emitting phosphors with high color purity were prepared by solid-state reaction method. The crystal structure and luminescence properties of the as-prepared phosphors were studied. This phosphor shows a satisfactory blue performance (peak at 453 nm) due to the {sup 1}D{sub 2} → {sup 3}F{sub 4} transition of Tm{sup 3+} excited by 357 nm light. Investigation of Tm{sup 3+} content dependent emission spectra indicates that x = 0.04 is the optimum doping content of Tm{sup 3+} ions in the CaBi{sub 2}B{sub 2}O{sub 7} host. The critical distance and the concentration quenching mechanism were also investigated. In particular, the color purity of as prepared sample was analyzed and the result shows that the color purity of CaBi{sub 2}B{sub 2}O{sub 7}:Tm{sup 3+} is higher than the commercial blue phosphor BaMgAl{sub 10}O{sub 17}:Eu{sup 2+} (BAM:Eu{sup 2+}) and the latest reported Tm{sup 3+} doped blue phosphors. The present work suggests that the CaBi{sub 2}B{sub 2}O{sub 7}:Tm{sup 3+} phosphor is a potential blue-emitting candidate for the application in the near-UV WLEDs.

  18. An UHPLC-MS/MS method for simultaneous quantification of human amyloid beta peptides Aβ1-38, Aβ1-40 and Aβ1-42 in cerebrospinal fluid using micro-elution solid phase extraction.

    Science.gov (United States)

    Lin, Ping-Ping; Chen, Wei-Li; Yuan, Fei; Sheng, Lei; Wu, Yu-Jia; Zhang, Wei-Wei; Li, Guo-Qing; Xu, Hong-Rong; Li, Xue-Ning

    2017-12-01

    Amyloid beta (Aβ) peptides in cerebrospinal fluid are extensively estimated for identification of Alzheimer's disease (AD) as diagnostic biomarkers. Unfortunately, their pervasive application is hampered by interference from Aβ propensity of self-aggregation, nonspecifically bind to surfaces and matrix proteins, and by lack of quantitive standardization. Here we report on an alternative Ultra-high performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) method for simultaneous measurement of human amyloid beta peptides Aβ1-38, Aβ1-40 and Aβ1-42 in cerebrospinal fluid (CSF) using micro-elution solid phase extraction (SPE). Samples were pre-processing by the mixed-mode micro-elution solid phase extraction and quantification was performed in the positive ion multiple reaction monitoring (MRM) mode using electrospray ionization. The stable-isotope labeled Aβ peptides 15 N 51 - Aβ1-38, 15 N 53 - Aβ1-40 and 15 N 55 - Aβ1-42 peptides were used as internal standards. And the artificial cerebrospinal fluid (ACSF) containing 5% rat plasma was used as a surrogate matrix for calibration curves. The quality control (QC) samples at 0.25, 2 and 15ng/mL were prepared. A "linear" regression (1/x 2 weighting): y=ax+b was used to fit the calibration curves over the concentration range of 0.1-20ng/mL for all three peptides. Coefficient of variation (CV) of intra-batch and inter-batch assays were all less than 6.44% for Aβ1-38, 6.75% for Aβ1-40 and 10.74% for Aβ1-42. The precision values for all QC samples of three analytes met the acceptance criteria. Extract recoveries of Aβ1-38, Aβ1-40 and Aβ1-42 were all greater than 70.78%, both in low and high QC samples. The stability assessments showed that QC samples at both low and high levels could be stable for at least 24h at 4°C, 4h at room temperature and through three freeze-thaw cycles without sacrificing accuracy or precision. And no significant carryover effect was observed. This validated UHPLC

  19. Detection of soil erosion within pinyon-juniper woodlands using Thematic Mapper (TM) satellite data

    Science.gov (United States)

    Price, Kevin P.; Ridd, Merrill K.

    1991-01-01

    The sensitivity of Landsat TM data for detecting soil erosion within pinyon-juniper woodlands, and the potential of the spectral data for assigning the universal soil loss equation (USLE) crop managemnent (C) factor to varying cover types within the woodlands are assessed. Results show greatly accelerated rates of soil erosion on pinyon-juniper sites. Percent cover by pinyon-juniper, total soil-loss, and total nonliving ground cover accounted for nearly 70 percent of the variability in TM channels 2, 3, 4, and 5. TM spectral data were consistently better predictors of soil erosion than the biotic and abiotic field variables. Satellite data were more sensitive to vegetation variation than the USLE C factor, and USLE was found to be a poor predictor of soil loss on pinyon-juniper sites. A new string-to-ground soil erosion prediction technique is introduced.

  20. Microstructure-property relationships in Al-Cu-Li-Ag-Mg Weldalite (tm) alloys, part 2

    Science.gov (United States)

    Langan, T. J.; Pickens, J. R.

    1991-01-01

    The microstructure and mechanical properties of the ultrahigh strength Al-Cu-Li-Ag-Mg alloy, Weldalite (tm) 049, were studied. Specifically, the microstructural features along with tensile strength, weldability, Young's modulus and fracture toughness were studied for Weldalite (tm) 049 type alloys with Li contents ranging from 1.3 to 1.9 wt. pct. The tensile properties of Weldalite 049 and Weldalite 049 reinforced with TiB2 particles fabricated using the XD (tm) process were also evaluated at cryogenic, room, and elevated temperatures. In addition, an experimental alloy, similar in composition to Weldalite 049 but without the Ag+Mg, was fabricated. The microstructure of this alloy was compared with that of Weldalite 049 in the T6 condition to assess the effect of Ag+Mg on nucleation of strengthening phases in the absence of cold work.

  1. Impact of Trace Minerals on Wound Healing of Footpad Dermatitis in Broilers.

    Science.gov (United States)

    Chen, Juxing; Tellez, Guillermo; Escobar, Jeffery; Vazquez-Anon, Mercedes

    2017-05-15

    Footpad dermatitis (FPD) is used in the poultry industry as an animal welfare criterion to determine stocking density. Trace minerals (TM) play a role in skin integrity and wound healing. This study evaluated the impact of TM on FPD and consisted of 3 treatments supplemented with 0 (NTM), low (LTM) and high (HTM) TM levels in the same basal diet. On d21, 71% birds in all treatments developed mild FPD and pens were top-dressed with dry litter to promote FPD healing. Compared to NTM, LTM reduced area under the curve (AUC) of FPD lesion scores during d21-42, HTM reduced the AUC of FPD lesion scores during d7-21 and d21-42. LTM improved growth performance on d14, HTM improved growth performance on d14 and d28. LTM and/or HTM increased gene expression of VEGF, TIMP3, TIMP4, MMP13, ITGA2, ITGA3 and CD40, which promoted collagen synthesis, deposition and organization; cell migration, matrix remodeling, and angiogenesis. LTM and/or HTM increased inflammation by upregulating TNFα and IL-1β during the early wound healing phase and reduced inflammation by downregulating IL-1β during the late wound healing phase. Our findings showed that TM not only improved growth performance but also reduced FPD development by promoting FPD wound healing.

  2. BACTEC MGIT 960 TM system for screening of Mycobacterium ...

    African Journals Online (AJOL)

    This study was aimed to evaluate the recent technique (BACTEC MGIT 960 TM system) for screening of Mycobacterium tuberculosis complex among cattle in Egypt. From the 1180 cattle examined in three different Governorates (El-Sharkia, El-Gharbia and El-Monefeia) by single intradermal tuberculin test, 29 animals ...

  3. Kappa. -electron capture probability in sup 167 Tm

    Energy Technology Data Exchange (ETDEWEB)

    Sree Krishna Murty, G.; Chandrasekhar Rao, M.V.S.; Radha Krishna, K.; Bhuloka Reddy, S.; Satyanarayana, G.; Ramana Rao, P.V.; Sastry, D.L. (Andhra Univ., Visakhapatnam (India). Labs. for Nuclear Research); Chintalapudi, S.N. (Variable Energy Cyclotron Centre, Calcutta (India))

    1990-07-01

    The {Kappa}-electron capture probability in the decay of {sup 167}Tm for the first-forbidden transition 1/2{sup +}{yields}3/2{sup -} was measured using the sum-coincidence method and employing a hyper-pure Ge system. The P{sub {Kappa}} value is found to be 0.835{plus minus}0.029, in agreement with the theoretical value of 0.829. (author).

  4. An ELISA using recombinant TmHSP70 for the diagnosis of Taenia multiceps infections in goats.

    Science.gov (United States)

    Wang, Yu; Nie, Huaming; Gu, Xiaobin; Wang, Tao; Huang, Xing; Chen, Lin; Lai, Weimin; Peng, Xuerong; Yang, Guangyou

    2015-09-15

    Infections with the tapeworm Taenia multiceps are problematic for ruminant farming worldwide. Here we develop a novel and rapid method for serodiagnosis of T. multiceps infections via an indirect ELISA (iELISA) that uses a heat shock protein, namely, TmHSP70. We extracted the total RNA of T. multiceps from the protoscoleces of cysts dissected from the brains of infected goats. Subsequently, we successfully amplified, cloned and expressed the TmHSP70 gene in Escherichia coli BL21 (DE3). Western blot analysis showed that the recombinant protein (∼34 kDa molecular weight) was recognized by the coenurosis positive serum. Given these initial, robust immunogenic properties for recombinant TmHSP protein, we assessed the ELISA-based serodiagnostic potential of this gene. The indirect ELISA was then optimized to 2.70 μg/well dilution for antigen and 1:80 dilution for serum,while the cut-off value is 0.446. We report that our novel TmHSP ELISA detected T. multiceps sera with a sensitivity of 1:10240 and a specificity of 83.3% (5/6). In a preliminary application, this assay correctly confirmed T. multiceps infection in 30 infected goats, consistent with the clinical examination. This study has revealed that our novel iELISA, which uses the rTmHSP protein, provides a rapid test for diagnosing coenurosis. Copyright © 2015 Elsevier B.V. All rights reserved.

  5. Exome-wide association study identifies a TM6SF2 variant that confers susceptibility to nonalcoholic fatty liver disease

    DEFF Research Database (Denmark)

    Kozlitina, Julia; Smagris, Eriks; Stender, Stefan

    2014-01-01

    Nonalcoholic fatty liver disease (NAFLD) is the most common form of liver disease. To elucidate the molecular basis of NAFLD, we performed an exome-wide association study of liver fat content. Three variants were associated with higher liver fat levels at the exome-wide significance level of 3.......6 × 10(-7): two in PNPLA3, an established locus for NAFLD, and one (encoding p.Glu167Lys) in TM6SF2, a gene of unknown function. The TM6SF2 variant encoding p.Glu167Lys was also associated with higher circulating levels of alanine transaminase, a marker of liver injury, and with lower levels of low...... knockdown of Tm6sf2 in mice increased liver triglyceride content by threefold and decreased very-low-density lipoprotein (VLDL) secretion by 50%. Taken together, these data indicate that TM6SF2 activity is required for normal VLDL secretion and that impaired TM6SF2 function causally contributes to NAFLD....

  6. Rheology of StelliteTM 21 Alloy in Semi-Solid State

    Directory of Open Access Journals (Sweden)

    Sołek K.

    2016-12-01

    Full Text Available The main objective of this study was to conduct an analysis of the rheological properties of StelliteTM 21 alloy in the semi-solid state, as the results could be used for identifying the appropriate temperature range for thixoforming of this alloy, and a secondary objective of the experimental work was the development of mathematical model of the alloy’s apparent viscosity. Such viscosity models are necessary for numerical simulations of the thixoforming processes. The StelliteTM 21 alloy exhibits high hardness and thus shaping in the semi-solid state is promising route of production of parts from this alloy. Within the confines of experimental work the measurement methods of the rheological properties at high temperatures was developed. They are based on the use of specially designed viscometer equipped with high temperature furnace.

  7. EMPHASIS(TM)/Nevada Unstructured FEM Implementation Version 2.1.1.

    Energy Technology Data Exchange (ETDEWEB)

    Turner, C. David; Pointon, Timothy D.; Cartwright, Keith

    2014-08-01

    EMPHASIS TM /NEVADA is the SIERRA/NEVADA toolkit implementation of portions of the EMP HASIS TM code suite. The purpose of the toolkit i m- plementation is to facilitate coupling to other physics drivers such as radi a- tion transport as well as to better manage code design, implementation, co m- plexity, and important verification and validation processes. This document describes the theory and implementation of the unstructured finite - element method solver , associated algorithms, and selected verification and valid a- tion . Acknowledgement The author would like to recognize all of the ALEGRA team members for their gracious and willing support through this initial Nevada toolkit - implementation process. Although much of the knowledge needed was gleaned from document a- tion and code context, they were always willing to consult personally on some of the less obvious issues and enhancements necessary.

  8. Effect of GutsyGum(tm), A Novel Gum, on Subjective Ratings of Gastro Esophageal Reflux Following A Refluxogenic Meal.

    Science.gov (United States)

    Brown, Rachel; Sam, Cecilia H Y; Green, Tim; Wood, Simon

    2015-06-01

    Chewing gum alleviates symptoms of gastro-esophageal reflux (GER) following a refluxogenic meal. GutsyGum(tm), a chewing gum developed to alleviate the symptoms of GER contains calcium carbonate, with a proprietary blend of licorice extract, papain, and apple cider vinegar (GiGs®). The efficacy of GutsyGum(tm) was determined in alleviating the symptoms of GER after a refluxogenic meal compared to placebo gum. This double-blind, placebo-controlled-crossover trial with a one-week washout between treatments had 24 participants with a history of GER consume a refluxogenic meal and then chew GutsyGum(tm) or placebo gum. Participants completed GER symptom questionnaires, consisting of symptom based 10 cm Visual Analogue Scales, immediately following the meal and then at regular intervals out to four hours postmeal. Adjusted mean ± SEM heartburn score (15-min postmeal to 240 min) was significantly lower in GutsyGum(tm) than in placebo gum treatment (0.81 ± 0.20 vs. 1.45 ± 0.20 cm; p = 0.034). Mean acid reflux score was significantly lower in GutsyGum(tm) than in placebo treatment (0.72 ± 0.19 vs. 1.46 ± 0.19 cm; p = 0.013). There were no significant differences for any of the secondary outcomes. However, pain approached significance with less pain reported in GutsyGum(tm) versus placebo treatment (0.4 ± 0.2 vs. 0.9 ± 0.2 cm; p = 0.081). Although nausea (p = 0.114) and belching (p = 0.154) were lower following GutsyGum(tm), the difference was not statistically significant. GutsyGum(tm) is more effective than a placebo gum in alleviating primary symptoms of heartburn and acid reflux (Clinical Trial Registration: ACTRN12612000973819).

  9. Upregulation of CRABP1 in human neuroblastoma cells overproducing the Alzheimer-typical Aβ42 reduces their differentiation potential

    Directory of Open Access Journals (Sweden)

    Weninger Annette

    2008-12-01

    Full Text Available Abstract Background Alzheimer's disease (AD is characterized by neurodegeneration and changes in cellular processes, including neurogenesis. Proteolytic processing of the amyloid precursor protein (APP plays a central role in AD. Owing to varying APP processing, several β-amyloid peptides (Aβ are generated. In contrast to the form with 40 amino acids (Aβ40, the variant with 42 amino acids (Aβ42 is thought to be the pathogenic form triggering the pathological cascade in AD. While total-Aβ effects have been studied extensively, little is known about specific genome-wide effects triggered by Aβ42 or Aβ40 derived from their direct precursor C99. Methods A combined transcriptomics/proteomics analysis was performed to measure the effects of intracellularly generated Aβ peptides in human neuroblastoma cells. Data was validated by real-time polymerase chain reaction (real-time PCR and a functional validation was carried out using RNA interference. Results Here we studied the transcriptomic and proteomic responses to increased or decreased Aβ42 and Aβ40 levels generated in human neuroblastoma cells. Genome-wide expression profiles (Affymetrix and proteomic approaches were combined to analyze the cellular response to the changed Aβ42- and Aβ40-levels. The cells responded to this challenge with significant changes in their expression pattern. We identified several dysregulated genes and proteins, but only the cellular retinoic acid binding protein 1 (CRABP1 was up-regulated exclusively in cells expressing an increased Aβ42/Aβ40 ratio. This consequently reduced all-trans retinoic acid (RA-induced differentiation, validated by CRABP1 knock down, which led to recovery of the cellular response to RA treatment and cellular sprouting under physiological RA concentrations. Importantly, this effect was specific to the AD typical increase in the Aβ42/Aβ40 ratio, whereas a decreased ratio did not result in up-regulation of CRABP1. Conclusion We

  10. The impact of translation-memory (TM) technology on cognitive processes

    DEFF Research Database (Denmark)

    Christensen, Tina Paulsen; Schjoldager, Anne

    2011-01-01

    The use of Translation-Memory (TM) technology and other translation software is bound to influence translators' cognitive processes. Unfortunately we still lack empirically founded knowledge of this. Our paper therefore presents and discusses the theoretical background, setup and preliminary...

  11. Characterization of the phantom material Virtual WaterTM in high-energy photon and electron beams

    International Nuclear Information System (INIS)

    McEwen, M.R.; Niven, D.

    2006-01-01

    The material Virtual Water TM has been characterized in photon and electron beams. Range-scaling factors and fluence correction factors were obtained, the latter with an uncertainty of around 0.2%. This level of uncertainty means that it may be possible to perform dosimetry in a solid phantom with an accuracy approaching that of measurements in water. Two formulations of Virtual Water TM were investigated with nominally the same elemental composition but differing densities. For photon beams neither formulation showed exact water equivalence--the water/Virtual Water TM dose ratio varied with the depth of measurement with a difference of over 1% at 10 cm depth. However, by using a density (range) scaling factor very good agreement ( TM at all depths was obtained. In the case of electron beams a range-scaling factor was also required to match the shapes of the depth dose curves in water and Virtual Wate TM . However, there remained a difference in the measured fluence in the two phantoms after this scaling factor had been applied. For measurements around the peak of the depth-dose curve and the reference depth this difference showed some small energy dependence but was in the range 0.1%-0.4%. Perturbation measurements have indicated that small slabs of material upstream of a detector have a small (<0.1% effect) on the chamber reading but material behind the detector can have a larger effect. This has consequences for the design of experiments and in the comparison of measurements and Monte Carlo-derived values

  12. TM9 and cannibalism: how to learn more about cancer by studying amoebae and invertebrates.

    Science.gov (United States)

    Fais, Stefano; Fauvarque, Marie-Odile

    2012-01-01

    Phagocytosis is used not only for immune defense but may also be used to obtain nutrients, as observed when tumor cells feed upon neighboring cells during "tumor cell cannibalism". The TM9 protein TM9SF4, important in canonical phagocytosis, is involved in this cannibalism by metastatic cells and may represent a novel therapeutic target. Copyright © 2011 Elsevier Ltd. All rights reserved.

  13. Nanosecond Q-switched operation of coupled Yb and Tm fibre lasers

    Energy Technology Data Exchange (ETDEWEB)

    Tsang, Yuen H [Laser Photonics Research Group, School of Physics and Astronomy, University of Manchester, Manchester M13 9PL (United Kingdom); Qamar, Fadi [Laser Photonics Research Group, School of Physics and Astronomy, University of Manchester, Manchester M13 9PL (United Kingdom); King, Terence A [Laser Photonics Research Group, School of Physics and Astronomy, University of Manchester, Manchester M13 9PL (United Kingdom); Ko, Do-Kyeong [Advanced Photonics Research Institute, Gwangju Institute of Science and Technology, 1 Oryong-dong, Buk-Gu, Gwangju 500-712 (Korea, Republic of); Lee, Jongmin [Advanced Photonics Research Institute, Gwangju Institute of Science and Technology, 1 Oryong-dong, Buk-Gu, Gwangju 500-712 (Korea, Republic of)

    2005-05-07

    A small scale coupled Yb-silica and Tm-silica fibre laser system is described with output at 1.9 {mu}m and with Q-switching using an acousto-optic modulator and also by mechanical optical modulation. The Yb-fibre laser pump source exhibited strong self-pulsation with high-intensity pulses due to stimulated Brillouin scattering. But regular Q-switched pulses were generated from the Tm-fibre laser with an energy of {approx}2.4 {mu}J and duration (FWHM) of {approx}280 ns for modulation frequencies of 1-20 kHz when using acousto-optic modulation. The main effects that limit the Q-switched pulse peak power are the onset of gain-switched pulsing during the low-Q state and strong pump excited state absorption.

  14. REGIONAL GEOLGICAL MAPPING IN TROPICAL ENVIRONMENTS USING LANDSAT TM AND SRTM REMOTE SENSING DATA

    Directory of Open Access Journals (Sweden)

    A. Beiranvand Pour

    2015-10-01

    Full Text Available Landsat Thematic Mapper (TM and Shuttle Radar Topography Mission (SRTM data were used to produce geological maps in tropical environments. Lineament, lithology and landform maps were produced for all states in peninsular Malaysia in this study. Kedah, Perak and Terengganu states have been selected as case studies to demonstrate the results of the data and techniques used. Directional filtering technique was applied to Landsat TM bands 4, 5 and 3 for lineament mapping. The lithology map was produced using Landsat TM bands combination consist of bands 4, 3 and 2. Digital elevation model and landform map were produced using SRTM data in 3 Dimension (3D and 2 Dimension (2D perspective views, respectively. The produced geological maps and the remote sensing data and methods applied in this study are mostly appropriate for hazard risk mapping applications and mineral exploration projects in the peninsular Malaysia and tropical environments.

  15. Evaluating the Effectiveness of the 2002-2003 NASA SCIence Files(TM) Program

    Science.gov (United States)

    Pinelli, Thomas E.; Lambert, Matthew A.; Williams, Amy C.

    2004-01-01

    NASA SCIence Files (tm) is a research-, inquiry-, and standards-based, integrated mathematics, science, and technology series of 60-minute instructional distance learning (television and web-based) programs for students in grades 3-5. Respondents who evaluated the programs in the 2002-2003 NASA SCIence Files (tm) series reported that (1) they used the programs in the series; (2) the goals and objectives for the series were met; (3) the programs were aligned with the national mathematics, science, and technology standards; (4) the program content was developmentally appropriate for grade level; and (5) the programs in the series enhanced and enriched the teaching of mathematics, science, and technology.

  16. MnTM-4-PyP modulates endogenous antioxidant responses and protects primary cortical neurons against oxidative stress.

    Science.gov (United States)

    Cheng, Kuo-Yuan; Guo, Fei; Lu, Jia-Qi; Cao, Yuan-Zhao; Wang, Tian-Chang; Yang, Qi; Xia, Qing

    2015-05-01

    Oxidative stress is a direct cause of injury in various neural diseases. Manganese porphyrins (MnPs), a large category of superoxide dismutase (SOD) mimics, shown universally to have effects in numerous neural disease models in vivo. Given their complex intracellular redox activities, detailed mechanisms underlying the biomedical efficacies are not fully elucidated. This study sought to investigate the regulation of endogenous antioxidant systems by a MnP (MnTM-4-PyP) and its role in the protection against neural oxidative stress. Primary cortical neurons were treated with MnTM-4-PyP prior to hydrogen peroxide-induced oxidative stress. MnTM-4-PyP increased cell viability, reduced intracellular level of reactive oxygen species, inhibited mitochondrial apoptotic pathway, and ameliorated endoplasmic reticulum function. The protein levels and activities of endogenous SODs were elevated, but not those of catalase. SOD2 transcription was promoted in a transcription factor-specific manner. Additionally, we found FOXO3A and Sirt3 levels also increased. These effects were not observed with MnTM-4-PyP alone. Induction of various levels of endogenous antioxidant responses by MnTM-4-PyP has indispensable functions in its protection for cortical neurons against hydrogen peroxide-induced oxidative stress. © 2014 John Wiley & Sons Ltd.

  17. Analysis of CMOS Compatible Cu-Based TM-Pass Optical Polarizer

    KAUST Repository

    Ng, Tien Khee; Khan, Mohammed Zahed Mustafa; Al-Jabr, Ahmad Ali; Ooi, Boon S.

    2012-01-01

    for the polarizer, it was found that the metal-insulator-metal (MIM) polarizer structure is superior compared to the insulator-metal-insulator polarizer structure due to its higher polarization extinction ratio (PER) and low insertion loss. An optimized MIM TM

  18. O papel da FIFA Fan FestTM na copa do mundo da África do Sul

    Directory of Open Access Journals (Sweden)

    Fernando Borges

    2013-12-01

    Full Text Available Em 2010, pela segunda vez a FIFA promoveu o evento FIFA Fan FestTM no país que sediou a Copa do Mundo, e pela primeira vez criou uma versão internacional do evento em grandes cidades ao redor do mundo. O presente trabalho faz uma descrição das FIFA Fan FestsTM, tendo em conta a sua forma organização, a interação do público, a International Fan FestTM e formas alternativas do mesmo evento. Essa descrição é feita colocando o evento dentro do quadro teórico dos megaeventos esportivos e as transformações nas quais estão inseridos.

  19. Preanesthetic assessment data do not influence the time for tracheal intubation with Airtraq(tm video laryngoscope in obese patients

    Directory of Open Access Journals (Sweden)

    Dante Ranieri Jr.

    2014-06-01

    Full Text Available Purpose: this study investigated the influence of anatomical predictors on difficult laryngoscopy and orotracheal intubation in obese patients by comparing Macintosh and Airtraq(tm laryngoscopes. Methods: from 132 bariatric surgery patients (body mass index = 35 kg m-1, cervical perimeter, sternomental distance, interincisor distance, and Mallampati score were recorded. The patients were randomized into two groups according to whether a Macintosh (n = 64 or an Airtraq(tm (n = 68 laryngoscope was used for tracheal intubation. Time required for intubation was the first outcome. Cormack-Lehane score, number of intubation attempts, the Macintosh blade used, any need for external tracheal compression or the use of gum elastic bougie were recorded. Intubation failure and strategies adopted were also registered. Results: intubation failed in two patients in the Macintosh laryngoscope group, and these patients were included as worst cases scenario. The intubation times were 36.9 + 22.8 s and 13.7 + 3.1 s for the Macintosh and Airtraq(tm laryngoscope groups (p < 0.01, respectively. Cormack-Lehane scores were also lower for the Airtraq(tm group. One patient in the Macintosh group with intubation failure was quickly intubated with the Airtraq(tm. Cervical circumference (p < 0.01 and interincisor distance (p < 0.05 influenced the time required for intubation in the Macintosh group but not in the Airtraq(tm group. Conclusion: in obese patients despite increased neck circumference and limited mouth opening, the Airtraq(tm laryngoscope affords faster tracheal intubation than the Macintosh laryngoscope, and it may serve as an alternative when conventional laryngoscopy fails.

  20. Detection of NASBA amplified bacterial tmRNA molecules on SLICSel designed microarray probes

    Directory of Open Access Journals (Sweden)

    Toome Kadri

    2011-02-01

    Full Text Available Abstract Background We present a comprehensive technological solution for bacterial diagnostics using tmRNA as a marker molecule. A robust probe design algorithm for microbial detection microarray is implemented. The probes were evaluated for specificity and, combined with NASBA (Nucleic Acid Sequence Based Amplification amplification, for sensitivity. Results We developed a new web-based program SLICSel for the design of hybridization probes, based on nearest-neighbor thermodynamic modeling. A SLICSel minimum binding energy difference criterion of 4 kcal/mol was sufficient to design of Streptococcus pneumoniae tmRNA specific microarray probes. With lower binding energy difference criteria, additional hybridization specificity tests on the microarray were needed to eliminate non-specific probes. Using SLICSel designed microarray probes and NASBA we were able to detect S. pneumoniae tmRNA from a series of total RNA dilutions equivalent to the RNA content of 0.1-10 CFU. Conclusions The described technological solution and both its separate components SLICSel and NASBA-microarray technology independently are applicative for many different areas of microbial diagnostics.

  1. Detection of tmRNA molecules on microarrays at low temperatures using helper oligonucleotides

    Directory of Open Access Journals (Sweden)

    Palta Priit

    2010-04-01

    Full Text Available Abstract Background The hybridization of synthetic Streptococcus pneumoniae tmRNA on a detection microarray is slow at 34°C resulting in low signal intensities. Results We demonstrate that adding specific DNA helper oligonucleotides (chaperones to the hybridization buffer increases the signal strength at a given temperature and thus makes the specific detection of Streptococcus pneumoniae tmRNA more sensitive. No loss of specificity was observed at low temperatures compared to hybridization at 46°C. The effect of the chaperones can be explained by disruption of the strong secondary and tertiary structure of the target RNA by the selective hybridization of helper molecules. The amplification of the hybridization signal strength by chaperones is not necessarily local; we observed increased signal intensities in both local and distant regions of the target molecule. Conclusions The sensitivity of the detection of tmRNA at low temperature can be increased by chaperone oligonucleotides. Due to the complexity of RNA secondary and tertiary structures the effect of any individual chaperone is currently not predictable.

  2. Optically stimulated luminescence properties of Tm3+ doped KMgF3 fluoro perovskite

    International Nuclear Information System (INIS)

    Camargo, L.; Marcazzo, J.; Perez C, L.; Cruz Zaragoza, E.; Martinez O, S. A.

    2017-10-01

    In this work the optically stimulated luminescence (OSL) properties of undoped and Tm 3+ doped KMgF 3 fluoro perovskite have been investigated for the first time. OSL efficiency for stimulation with different wavelengths has been analyzed for each compound. The maximum OSL emission was found with blue light stimulation. The radioluminescence (Rl) spectra have shown two emission peaks at 455 and 360 nm, which can be ascribed to the 1 D 2 - 3 F 4 and 1 D 2 - 3 H 6 transitions of the Tm 3+ cations. It has been found that doping with Thulium 0.5 mol % renders the most intense OSL emission. Furthermore, several dosimetric properties such as OSL response as a function of dose, reproducibility of the OSL signal after several cycles of irradiation readout and the minimum detectable dose have been investigated. Finally, the OSL response of KMgF 3 : Tm 3+ has been compared to that of commercial Al 2 O 3 :C and the possible application of this fluoro perovskite to OSL dosimetry has been evaluated. (Author)

  3. Detection of NASBA amplified bacterial tmRNA molecules on SLICSel designed microarray probes

    LENUS (Irish Health Repository)

    Scheler, Ott

    2011-02-28

    Abstract Background We present a comprehensive technological solution for bacterial diagnostics using tmRNA as a marker molecule. A robust probe design algorithm for microbial detection microarray is implemented. The probes were evaluated for specificity and, combined with NASBA (Nucleic Acid Sequence Based Amplification) amplification, for sensitivity. Results We developed a new web-based program SLICSel for the design of hybridization probes, based on nearest-neighbor thermodynamic modeling. A SLICSel minimum binding energy difference criterion of 4 kcal\\/mol was sufficient to design of Streptococcus pneumoniae tmRNA specific microarray probes. With lower binding energy difference criteria, additional hybridization specificity tests on the microarray were needed to eliminate non-specific probes. Using SLICSel designed microarray probes and NASBA we were able to detect S. pneumoniae tmRNA from a series of total RNA dilutions equivalent to the RNA content of 0.1-10 CFU. Conclusions The described technological solution and both its separate components SLICSel and NASBA-microarray technology independently are applicative for many different areas of microbial diagnostics.

  4. High-power ultralong-wavelength Tm-doped silica fiber laser cladding-pumped with a random distributed feedback fiber laser.

    Science.gov (United States)

    Jin, Xiaoxi; Du, Xueyuan; Wang, Xiong; Zhou, Pu; Zhang, Hanwei; Wang, Xiaolin; Liu, Zejin

    2016-07-15

    We demonstrated a high-power ultralong-wavelength Tm-doped silica fiber laser operating at 2153 nm with the output power exceeding 18 W and the slope efficiency of 25.5%. A random distributed feedback fiber laser with the center wavelength of 1173 nm was employed as pump source of Tm-doped fiber laser for the first time. No amplified spontaneous emissions or parasitic oscillations were observed when the maximum output power reached, which indicates that employing 1173 nm random distributed feedback fiber laser as pump laser is a feasible and promising scheme to achieve high-power emission of long-wavelength Tm-doped fiber laser. The output power of this Tm-doped fiber laser could be further improved by optimizing the length of active fiber, reflectivity of FBGs, increasing optical efficiency of pump laser and using better temperature management. We also compared the operation of 2153 nm Tm-doped fiber lasers pumped with 793 nm laser diodes, and the maximum output powers were limited to ~2 W by strong amplified spontaneous emission and parasitic oscillation in the range of 1900-2000 nm.

  5. Index matching of TE and TM modes in organic multilayer waveguides

    Science.gov (United States)

    Thompson, Jonathan; Schmitzer, Heidrun; Wagner, Hans Peter

    We investigate transverse electric (TE) and magnetic (TM) mode propagation in organic multilayers consisting of aluminum quinoline (Alq3) and perylenetetracarboxylic dianhydride (PTCDA). In particular, we analyze two multilayer waveguides, Alq3-PTCDA-Alq3 and PTCDA-Alq3-PTCDA, engineered to give index matching according to modeling. The waveguides were grown on a glass substrate via organic molecular beam deposition. Fabry-Perot oscillations observed from reflection measurements were used to confirm the individual layer thicknesses. We were able to observe refractive index matching between TE0 and TE1, as well as TE2 and TE3 modes for the PTCDA-Alq3-PTCDA waveguide due to the light propagation through the top and bottom PTCDA layers, respectively. In addition, we were able to match TE1 and TM1, as well as TE3 and TM3 modes in the Alq3-PTCDA-Alq3 multilayer due to the birefringence of the PTCDA layer. Furthermore, we are able to create mode matching for a range of wavelengths due to the similar effective refractive index dispersion of different waveguide modes. The ability to phase match different waveguide modes opens a wide range of potential applications including polarization-insensitive propagation and mode switching by adding a thin magnetic metal film within the waveguide and applying an external magnetic field.

  6. New nuclear data group constant sets for fusion reactor nuclear analyses based on JENDL-4.0 and FENDL-3.0

    International Nuclear Information System (INIS)

    Konno, Chikara; Ohta, Masayuki; Kwon, Saerom; Ochiai, Kentaro; Sato, Satoshi

    2015-01-01

    We have produced new nuclear data group constant sets from JENDL-4.0 and FENDL-3.0 for fusion reactor nuclear analyses; FUSION-J40-175, FUSION-F30-175 (40 materials, neutron 175 groups, gamma 42 groups), FUSION-J40-42 and FUSION-F30-42 (40 materials, neutron 42 groups, gamma 21 groups). MATXS files of JENDL-4.0 and FENDL-3.0 were newly produced with the NJOY2012 code. FUSION-J40-175, FUSION-J40-42, FUSION-F30-175 and FUSION-F30-42 were produced with the TRANSX code. KERMA factors, DPA and gas production cross-section data were also prepared from the MATXS files with TRANSX. Test calculations were carried out in order to validate these nuclear group constant sets. They suggested that these group constant sets had no problem. (author)

  7. Equivalente esférico e valores da espessura da camada de fibras nervosas obtidas com o GDX TM Scanning Laser System® Spherical equivalent and nerve fiber layer thickness assessed with GDX TM Scanning Laser System®

    Directory of Open Access Journals (Sweden)

    Lênio Souza Alvarenga

    1999-12-01

    Full Text Available Objetivo: Estudar a influência do equivalente esférico nos valores obtidos pelo GDX TM Scanning Laser System®. Métodos: Foram avaliados 41 olhos de 41 voluntários sem doenças oculares e com campo visual sem alterações. Foi realizada a polarimetria de varredura a laser com o GDX TM Scanning Laser System® de acordo com as instruções contidas no manual do aparelho. Foram comparados os valores obtidos nesse exame em um grupo de pacientes com equivalente esférico positivo e em um outro com este valor nulo ou negativo, pelo teste de Mann-Whitney. Resultados: Não se verificou diferença estatística entre os valores obtidos nos olhos de pacientes do grupo I e os do grupo II. Não foi encontrada correlação entre o equivalente esférico e os valores obtidos com o GDX TM Scanning Laser System®. Conclusões: Na amostra estudada não houve diferença estatística entre os valores obtidos em um grupo de olhos com equivalente esférico positivo e outro com este valor negativo ou nulo, usando-se o GDX TM Scanning Laser System®.Purpose: To evaluate the effect of spherical equivalent on the acquisition of nerve fiber layer (NFL thickness with GDX TM Scanning Laser System®. Methods: Forty-one eyes of 41 volunteers were enrolled in this study. All of them presented with no ocular disease and no visual field defect. The NFL thickness was measured with GDX TM Scanning Laser System® as described in its manual. The values obtained in a group of volunteers with negative spherical equivalent (group I were compared to those from a group with a positive spherical equivalent (group II by the Mann-Whitney test. Results: There was no statistical difference between mea-surements in eyes of group I and those in group II. The NFL thickness measurements were not correlated with the sphe-rical equivalent. Conclusions: In the studied group there was no statistical difference in the GDX TM Scanning Laser System® parameters related to spherical equivalent.

  8. Monitoring tensile damage evolution in Nextel 312/BlackglasTM composites

    International Nuclear Information System (INIS)

    Kim, Jeongguk; Liaw, Peter K.

    2005-01-01

    Tensile damage evolution was monitored with the aid of nondestructive evaluation (NDE) techniques. Several NDE methods, such as ultrasonic testing (UT), infrared (IR) thermography, and acoustic emission (AE) techniques, were employed to analyze damage evolution during tensile testing of Nextel 312/Blackglas TM composites. Prior to tensile testing, UT was used to characterize the initial defect distribution of the samples. During tensile testing, AE sensors and an IR camera were used for in situ monitoring of the progressive damage of the samples. AE provided the amounts of damage evolution in terms of the AE intensity and/or energy, and the IR camera was used to obtain the temperature changes during the test. Microstructural characterization using scanning electron microscopy (SEM) was performed to investigate the fracture mechanisms and modes of Nextel 312/Blackglas TM samples. Moreover, SEM characterization was used to document failure behavior, and to show comparable results with NDE signatures

  9. Characteristics of "Tween" Participants and Non-Participants in the VERB[TM] Summer Scorecard Physical Activity Promotion Program

    Science.gov (United States)

    Nickelson, Jen; Alfonso, Moya L.; McDermott, Robert J.; Bumpus, Elizabeth C.; Bryant, Carol A.; Baldwin, Julie A.

    2011-01-01

    Creating community-based opportunities for youth to be physically active is challenging for many municipalities. A Lexington, Kentucky community coalition designed and piloted a physical activity program, "VERB[TM] summer scorecard (VSS)", leveraging the brand equity of the national VERB[TM]--It's What You Do! campaign. Key elements of…

  10. Influence of Al on the magnetic properties of TmCo{sub 4}Al compound, a magnetic and neutron diffraction study

    Energy Technology Data Exchange (ETDEWEB)

    Laslo, A. [CNRS, Inst. Néel, F-38042 Grenoble (France); Univ. Grenoble Alpes, Inst. Néel, F-38042 Grenoble (France); Babes-Bolyai University, Faculty of Physics, 400084 Cluj-Napoca (Romania); Pop, V. [Babes-Bolyai University, Faculty of Physics, 400084 Cluj-Napoca (Romania); Isnard, O. [CNRS, Inst. Néel, F-38042 Grenoble (France); Univ. Grenoble Alpes, Inst. Néel, F-38042 Grenoble (France)

    2015-03-25

    Highlights: • The existence of a compensation temperature is found for TmCo{sub 4}Al. • The crystal structure and its thermal evolution are analysed by X-ray and neutron diffraction. • The ferrimagnetic magnetic structure of TmCo{sub 4}Al is established. • Magnetic properties are determined. • Significant coercivity is reported for TmCo{sub 4}Al. - Abstract: The structural and magnetic properties of the TmCo{sub 4}Al compound are presented as deduced from magnetic measurements, X-ray and neutron powder diffraction. The crystal structure is obtained in the light of Rietveld refinement of the neutron powder diffraction pattern. The symmetry of the CaCu{sub 5} structure is preserved and the Al atom is found to substitute the Co one exclusively on the 3g atomic position. Thermal expansion of the crystal lattice is reported, the temperature variation occurring mostly along the basal hexagonal plane. This compound exhibits a ferrimagnetic structure, the Tm and Co magnetic moments being coupled antiparallel. An ordering temperature of 511 K is found. The thermal dependence of the Tm magnetic moment is obtained down to 4 K. A compensation of the two sublattice magnetization is found at 75 K, a feature induced by the Al for Co substitution and not observed in the corresponding TmCo{sub 5} compound. Magnetization curves reveal large coercivity values at low temperature such as 2.48 T at 2 K.

  11. Blue and red emission in wide band gap BaZrO{sub 3}:Yb{sup 3+},Tm{sup 3+}

    Energy Technology Data Exchange (ETDEWEB)

    Borja-Urby, R. [Centro de Investigaciones en Optica, A. C., C. P. 37150 Leon, Gto. (Mexico); Diaz-Torres, L.A., E-mail: ditlacio@cio.mx [Centro de Investigaciones en Optica, A. C., C. P. 37150 Leon, Gto. (Mexico); Salas, P. [Centro de Fisica Aplicada y Tecnologia Avanzada, Universidad Nacional Autonoma de Mexico, A. P. 1-1010, Queretaro 76000 (Mexico); Vega-Gonzalez, M. [Centro de Geociencias-Universidad Nacional Autonoma de Mexico, A. P. 1-1010, Queretaro 76000 (Mexico); Angeles-Chavez, C. [Instituto Mexicano del Petroleo, Programa de Ingenieria Molecular, Cd. Mexico D.F. 07730 (Mexico)

    2010-10-25

    Under NIR excitation at 967 intense blue and red photoluminescence (PL) emissions are observed at room temperature in codoped Tm{sup 3+}-Yb{sup 3+} barium zirconate (BaZrO{sub 3}:Yb,Tm) powders. Powders were prepared by a simple hydrothermal method, and present a wide band gap that depends on the total rare earth content due to the degree of disorder induced in the BaZrO{sub 3} lattice by the substitution of the rare earth ions. Rietveld refinements of the XRD patterns indicated the presence of primary nanocrystallites with sizes between 50 and 70 nm depending on the Tm{sup 3+} content. Scanning transmission electron microscopy (STEM) shows that these primary particles self-aggregated in larger secondary particles which present a regular morphology with sizes around 1 {mu}m. The intense blue and red PL emissions in BaZrO{sub 3} powders under 967 nm excitation are governed by energy transfer processes from Yb{sup 3+} ions to Tm{sup 3+} ions and crossrelaxation among Tm{sup 3+} ions.

  12. Fast neutron responses of CaF2:Tm Teflon TLD discs of different thicknesses

    International Nuclear Information System (INIS)

    Pradhan, A.S.; Hoffmann, W.

    1986-01-01

    The fact that in CaF 2 :Tm (TLD-300) the ratio of the heights of thermoluminescence (TL) glow peaks at 240 0 C and 150 0 C is greater for irradiations by high LET radiations than by gamma rays has been found useful for the simultaneous and separate measurement of fast neutron and gamma ray absorbed doses. A recent study has indicated that the mixed field dosimetric characteristics of CaF 2 :Tm could be significantly improved by using thin TLDs. In the present study, CaF 2 :Tm Teflon TLD discs of thickness as low as 0.05 mm were evaluated. The thin discs could be read out by using normal planchette heating if a 400 0 C heat treatment is given to the discs prior to irradiation and TL readout. Influence of encapsulation of thin dosemeters was studied and their utility in situations such as interface dosimetry is discussed. (author)

  13. In vitro fibrillization of Alzheimer’s amyloid-β peptide (1-42)

    Energy Technology Data Exchange (ETDEWEB)

    Tiiman, Ann [Department of Gene Technology, Tallinn University of Technology, Tallinn 12618 (Estonia); Department of Biochemistry and Biophysics, Arrhenius Laboratories, Stockholm University, Stockholm, 106 91 (Sweden); Krishtal, Jekaterina; Palumaa, Peep; Tõugu, Vello, E-mail: vello.tougu@ttu.ee [Department of Gene Technology, Tallinn University of Technology, Tallinn 12618 (Estonia)

    2015-09-15

    The amyloid deposition in the form of extracellular fibrillar aggregates of amyloid-β (Aβ) peptide is a critical pathological event in Alzheimer’s disease. Here, we report a systematic investigation of the effects of environmental factors on the kinetics of Aβ fibrillization in vitro. The effects of Aβ42 peptide concentration, temperature, pH, added solvents and the ratio of Aβ40 and Aβ42 on the peptide fibrillization under agitated conditions was studied. The analysis show that the rate of fibril growth by monomer addition is not limited by diffusion but by rearrangement in the monomer structure, which is enhanced by low concentrations of fluorinated alcohols and characterized by the activation energy of 12 kcal/mol. Fibrillization rate decreases at pH values below 7.0 where simultaneous protonation of His 13 and 14 inhibits fibril formation. The lag period for Aβ42 was only twofold shorter and the fibril growth rate twofold faster than those of Aβ40. Lag period was shortened and the fibrillization rate was increased only at 90% content of Aβ42.

  14. High-pressure syntheses of lanthanide polysulfides and polyselenides LnX_1_._9 (Ln = Gd-Tm, X = S, Se)

    International Nuclear Information System (INIS)

    Mueller, Carola J.; Schwarz, Ulrich; Doert, Thomas

    2012-01-01

    The polysulfides LnS_1_._9 and polyselenides LnSe_1_._9 of the lanthanide metals from gadolinium to thulium were prepared by high-pressure high-temperature synthesis. The compounds adopt the tetragonal CeSe_1_._9 structure type in space group P4_2/n (No. 86) with lattice parameters of 8.531 Aa ≤ a ≤ 8.654 Aa and 15.563 Aa ≤ c ≤ 15.763 Aa for the sulfides and 8.869 Aa ≤ a ≤ 9.076 Aa and 16.367 Aa ≤ c ≤ 16.611 Aa for the selenides. The atomic pattern consists of puckered double slabs [LnX]"+ and planar chalcogenide layers with ten possible chalcogen positions, of which eight are occupied by chalcogen atoms forming dinuclear X_2"2"- dianions, one by a single X"2"- ion and one remaining vacant. This resembles a √5 x √5 x 2 superstructure of the ZrSSi aristotype. Structural relationships to the aristotype and the related lanthanide polychalcogenides LnX_2_-_δ (Ln = La-Tm, X = S-Te, δ = 0 - 0.3) are discussed. The samples synthesized under high-pressure conditions (p > 1 GPa) decompose slowly under release of sulfur or selenium at ambient conditions. The crystal structure of a partially degraded thulium-polysulfide sample can be described as an incommensurate variant of the original TmS_1_._9 motif. Additionally, the isostructural ternary compound Gd(S_1_-_xSe_x)_1_._9 was synthesized and characterized by powder X-ray diffraction. (Copyright copyright 2012 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  15. TmDOTA-tetraglycinate encapsulated liposomes as pH-sensitive LipoCEST agents.

    Directory of Open Access Journals (Sweden)

    Ana Christina L Opina

    Full Text Available Lanthanide DOTA-tetraglycinate (LnDOTA-(gly₄⁻ complexes contain four magnetically equivalent amide protons that exchange with protons of bulk water. The rate of this base catalyzed exchange process has been measured using chemical exchange saturation transfer (CEST NMR techniques as a function of solution pH for various paramagnetic LnDOTA-(gly₄⁻ complexes to evaluate the effects of lanthanide ion size on this process. Complexes with Tb(III, Dy(III, Tm(III and Yb(III were chosen because these ions induce large hyperfine shifts in all ligand protons, including the exchanging amide protons. The magnitude of the amide proton CEST exchange signal differed for the four paramagnetic complexes in order, Yb>Tm>Tb>Dy. Although the Dy(III complex showed the largest hyperfine shift as expected, the combination of favorable chemical shift and amide proton CEST linewidth in the Tm(III complex was deemed most favorable for future in vivo applications where tissue magnetization effects can interfere. TmDOTA-(gly₄⁻ at various concentrations was encapsulated in the core interior of liposomes to yield lipoCEST particles for molecular imaging. The resulting nanoparticles showed less than 1% leakage of the agent from the interior over a range of temperatures and pH. The pH versus amide proton CEST curves differed for the free versus encapsulated agents over the acidic pH regions, consistent with a lower proton permeability across the liposomal bilayer for the encapsulated agent. Nevertheless, the resulting lipoCEST nanoparticles amplify the CEST sensitivity by a factor of ∼10⁴ compared to the free, un-encapsulated agent. Such pH sensitive nano-probes could prove useful for pH mapping of liposomes targeted to tumors.

  16. Genetic variation in the immunosuppression pathway genes and breast cancer: a pooled analysis of 42,510 cases and 40,577 controls from the Breast

    OpenAIRE

    Lei, Jieping; Rudolph, Anja; Moysich, Kirsten B; Behrens, Sabine; Goode, Ellen L; Bolla, Manjeet K; Dennis, Joe; Dunning, Alison Margaret; Easton, Douglas Frederick; Wang, Qin; Benitez, Javier; Hopper, John L; Southey, Melissa C; Schmidt, Marjanka K; Broeks, Annegien

    2015-01-01

    Immunosuppression plays a pivotal role in assisting tumors to evade immune destruction and promoting tumor development. We hypothesized that genetic variation in the immunosuppression pathway genes may be implicated in breast cancer tumorigenesis. We included 42,510 female breast cancer cases and 40,577 controls of European ancestry from 37 studies in the Breast Cancer Association Consortium (2015) with available genotype data for 3595 single nucleotide polymorphisms (SNPs) in 133 candidate g...

  17. Efficient propagation of TM polarized light in photonic crystal components exhibiting band gaps for TE polarized light

    DEFF Research Database (Denmark)

    Borel, Peter Ingo; Frandsen, Lars Hagedorn; Thorhauge, Morten

    2003-01-01

    We have investigated the properties of TM polarized light in planar photonic crystal waveguide structures, which exhibit photonic band gaps for TE polarized light. Straight and bent photonic crystal waveguides and couplers have been fabricated in silicon-on-insulator material and modelled using a 3......D finite-difference-time-domain method. The simulated spectra are in excellent agreement with the experimental results, which show a propagation loss as low as 2.5±4 dB/mm around 1525 nm and bend losses at 2.9±0.2 dB for TM polarized light. We demonstrate a high coupling for TM polarized light...

  18. Leksell Gammaknife PerfexionTM and discussion on clinical dosimetry

    International Nuclear Information System (INIS)

    Eriksson, O.; Johansson, J.; Kjaell, P.; Lundin, A.; Nordstroem, H.

    2008-01-01

    Leksell GammaKnife has been a well established treatment modality for more than 20 years in the field of stereotactic radiosurgery. In 2006 a new model was presented that introduces a number of new features at the same time as it keeps all the beneficial features of the other models. This new model, Leksell GammaKnife Perfexion TM , has a significantly improved radiation shielding capacity towards patient and treatment room walls, all collimators are built into the unit and therefore no changes of collimator helmets between shots are needed, the sources are placed on eight individually controllable mechanical structures meaning that one shot may be composed of several different collimator sizes, the patient is moved into position by the entire couch therefore increasing patient comfort significantly. This presentation aims at describing the entire Leksell GammaKnife Perfexion TM system from a physicist's point of view: design of the collimator system, dosimetry, design of radiation shielding, leakage field in the treatment room, design of secondary barriers, applicable QA-procedures, calibration -dosimetric and mechanical

  19. Linkage studies on 13 biochemical loci and 2 coat color loci in a [(BN x TM) x TM] backcross progeny of the rat (Rattus norvegicus).

    Science.gov (United States)

    Yamada, J; Hamada, S; Bender, K; Adams, M

    1986-10-01

    In a [(BN X TM) X TM] backcross progeny of rats, nine significant linkage associations were found among 105 pairwise combinations of 15 loci. After comparing this with other published data and data of personal communications, we considered that the d gene we tentatively designated may be identical to the gene for pink-eyed dilution (p), and that the associations of Gc-Hbb, RT1-h, and Gc-Fh were due to chance rather than real linkage. The linkages obtained in this study, therefore, were Hbb-p (26.5 +/- 5.5) in LG I, Mup-1-Acon-1 (12.5 +/- 4.1) in LG II, Hao-1-Svp-1 (23.8 +/- 6.6) in LG IV, Es-1-Es-3 (17.2 +/- 4.7) in LG V, h-Gc (10.9 +/- 3.3) in LG VI, and Fh-Pep-3 (32.3 +/- 5.9) in LG X.

  20. Probing structure, thermochemistry, electron affinity, and magnetic moment of thulium-doped silicon clusters TmSi n (n = 3-10) and their anions with density functional theory.

    Science.gov (United States)

    Huang, Xintao; Yang, Jucai

    2017-12-26

    The most stable structures and electronic properties of TmSi n (n = 3-10) clusters and their anions have been probed by using the ABCluster global search technique combined with the PBE, TPSSh, and B3LYP density functional methods. The results revealed that the most stable structures of neutral TmSi n and their anions can be regarded as substituting a Si atom of the ground state structure of Si n + 1 with a Tm atom. The reliable AEAs, VDEs and simulated PES of TmSi n (n = 3-10) are presented. Calculations of HOMO-LUMO gap revealed that introducing Tm atom to Si cluster can improve photochemical reactivity of the cluster. The NPA analyses indicated that the 4f electron of Tm atom in TmSi n (n = 3-10) and their anions do not participate in bonding. The total magnetic moments of TmSi n are mainly provided by the 4f electrons of Tm atom. The dissociation energy of Tm atom from the most stable structure of TmSi n and their anions has been calculated to examine relative stability.

  1. The Effects of TM on Concurrent Heart Rate, Peripheral Blood Pulse Volume, and the Alpha Wave Frequency.

    Science.gov (United States)

    Lukas, Jerome S.

    Through observation of 26 subjects over a 3 month period, this research project measured the effects of transcendental meditation (TM) on concurrent heart rate, peripheral blood pulse volume, and the alpha wave frequency. The subjects were assigned randomly to three groups. One group practiced TM as prescribed by the International Meditation…

  2. On the character of the intense 4d → f resonances in atomic La and Tm

    International Nuclear Information System (INIS)

    Radtke, E.R.

    1979-01-01

    Observations of the 4 d absorption spectra of atomic La and Tm are reported. It is shown that the RPAE predictions for the 4d→ epsilonf cross section in La I are currently closest to experiment. In Tm I a quite sharp autoionising resonance is observed. The differences between the two spectra are discussed with reference to ab initio calculations. (author)

  3. Characterization of thermoluminescent response of Al2O3:Tm/Teflon for gamma rays dosimetry

    International Nuclear Information System (INIS)

    Carvalho Junior, Alvaro B. de; Barros, Vinicius S.M. de; Elihimas, Diego Rafael M.; Khoury, Helen J.; Azevedo, Walter M. de

    2011-01-01

    In this work, α-Al 2 O 3 doped with Tm 3+ was prepared by combustion synthesis techniques for thermoluminescent (TL) ionizing radiation dosimetry applications. After this, Al 2 O 3 :Tm (0.1%) pellets were manufactured from a 2:1 homogeneous mixture of Al 2 O 3 :Tm (0.1%) and powdered Teflon (PTFE). Ten pellets were used to characterize the dosimetric properties. The dosimetric characterization was performed by analyses of the reproducibility, sensitivity of the TL response vs. dose between 1 and 10 Gy to 60 Co source and fading. The results showed a glow curve with a peak near to 225 deg C, a linear TL response with the gamma radiation dose in the range investigated and a reproducibility < 10%. These results indicate a potential use of these pellets for gamma radiation dosimetry. (author)

  4. DesinFix TM 135 in fermentation process for bioethanol production

    Directory of Open Access Journals (Sweden)

    Dorothee Barth

    2014-01-01

    Full Text Available Brazil has the world's largest ethanol production from sugarcane, but bacterial contamination decreases the ethanol yields. It was shown that the biocide DesinFixTM 135 can reduce the contamination without decreasing the yeasts' viability or negatively affecting the ethanol production.

  5. Caelyx (TM) in malignant mesothelioma : A phase II EORTC study

    NARCIS (Netherlands)

    Baas, P; van Meerbeeck, J; Groen, H; Schouwink, H; Burgers, S; Daamen, S; Giaccone, G

    Background: The use of doxorubicin has shown some activity in malignant mesothelioma but prolonged administration is hampered by cardiotoxicity. Caelyx(TM), a new liposomal and pegylated form of doxorubicin has shown a better pharmacokinetic and toxic profile then doxorubicin. In a phase II study,

  6. Investigations of mechanical, electronic, and magnetic properties of non-magnetic MgTe and ferro-magnetic Mg0.75TM0.25Te (TM = Fe, Co, Ni): An ab-initio calculation

    International Nuclear Information System (INIS)

    Mahmood, Q; Alay-e-Abbas, S M; Mahmood, I; Noor, N A; Asif, Mahmood

    2016-01-01

    The mechanical, electronic and magnetic properties of non-magnetic MgTe and ferro-magnetic (FM) Mg 0.75 TM 0.25 Te (TM = Fe, Co, Ni) in the zinc-blende phase are studied by ab-initio calculations for the first time. We use the generalized gradient approximation functional for computing the structural stability, and mechanical properties, while the modified Becke and Johnson local (spin) density approximation (mBJLDA) is utilized for determining the electronic and magnetic properties. By comparing the energies of non-magnetic and FM calculations, we find that the compounds are stable in the FM phase, which is confirmed by their structural stabilities in terms of enthalpy of formation. Detailed descriptions of elastic properties of Mg 0.75 TM 0.25 Te alloys in the FM phase are also presented. For electronic properties, the spin-polarized electronic band structures and density of states are computed, showing that these compounds are direct bandgap materials with strong hybridizations of TM 3d states and Te p states. Further, the ferromagnetism is discussed in terms of the Zener free electron model, RKKY model and double exchange model. The charge density contours in the (110) plane are calculated to study bonding properties. The spin exchange splitting and crystal field splitting energies are also calculated. The distribution of electron spin density is employed in computing the magnetic moments appearing at the magnetic sites (Fe, Co, Ni), as well as at the non-magnetic sites (Mg, Te). It is found that the p–d hybridization causes not only magnetic moments on the magnetic sites but also induces negligibly small magnetic moments at the non-magnetic sites. (paper)

  7. White light emission from Tm3+/Dy3+ co-doped oxyfluoride germanate glasses under UV light excitation

    International Nuclear Information System (INIS)

    Lakshminarayana, G.; Yang Hucheng; Qiu Jianrong

    2009-01-01

    In this paper, we report on the absorption and photoluminescence properties of Tm 3+ /Dy 3+ ions co-doped oxyfluoride germanate glasses for white light emission. The X-ray diffraction (XRD) and differential thermal analysis (DTA) profiles of the host glass have been carried out to confirm its structure and thermal stability. From the measured absorption spectra, Judd-Ofelt (J-O) intensity parameters (Ω 2 , Ω 4 and Ω 6 ) have been evaluated for Tm 3+ and Dy 3+ ions. A combination of blue, yellow and red emissions has emerged in these glasses, which allows the observation of bright white light when the glasses are excited by the ultraviolet light. The white light luminescence colour could be changed by varying the excitation wavelength. Also, various colours of luminescence, including white light, can be easily tuned by adjusting the concentrations of Tm 3+ or Dy 3+ ions in the co-doped glasses. Concentration quenching effect was also investigated and possible energy transfer mechanism from Dy 3+ →Tm 3+ ions was explained which is also confirmed by the decay lifetime measurements. - Graphical Abstract: A combination of blue, yellow and red emissions has emerged from Tm 3+ /Dy 3+ co-doped glasses, which allows the observation of bright white light and makes them as excellent candidates applicable in the solid-state multi-colour three-dimensional display.

  8. Enhanced broadband upconversion emission and 23 dB optical gain at 780 nm in Tm3+/Nd3+ codoped optical fiber

    International Nuclear Information System (INIS)

    Fan, Weiwei; Chen, Shuyue; Htein, Lin; Han, Won-Taek

    2015-01-01

    Maximum gain of 23 dB at 780 nm and a broadband optical gain with full width at half maximum (FWHM) of 88 nm (761–849 nm) were obtained from the Tm 3+ /Nd 3+ codoped fiber upon pumping at 1550 nm. The enhancement of the upconversion emission stretching from 730 to 970 nm was observed in the Tm 3+ /Nd 3+ codoped fiber due to the energy transfer from Tm 3+ to Nd 3+ ions. - Highlights: • We fabricated the Tm 3+ /Nd 3+ codoped silica based fiber. • The broadband upconversion emission was observed with 1550 nm pumping. • Maximum gain of 23 dB was observed at 780 nm from the Tm 3+ /Nd 3+ codoped fiber. • The gain bandwidth of the upconversion emission was largely increased due to energy transfer process

  9. Tm3+/Yb3+ co-doped tellurite glass with silver nanoparticles for 1.85 μm band laser material

    Science.gov (United States)

    Huang, Bo; Zhou, Yaxun; Cheng, Pan; Zhou, Zizhong; Li, Jun; Jin, Wei

    2016-10-01

    Tm3+/Yb3+ co-doped tellurite glasses with different silver nanoparticles (Ag NPs) concentrations were prepared using the conventional melt-quenching technique and characterized by the UV/Vis/NIR absorption spectra, 1.85 μm band fluorescence emission spectra, transmission electron microscopy (TEM) images, differential scanning calorimeter (DSC) curves and X-ray diffraction (XRD) patterns to investigate the effects of Ag NPs on the 1.85 μm band spectroscopic properties of Tm3+ ions, thermal stability and structural nature of glass hosts. Under the excitation of 980 nm laser diode (LD), the 1.85 μm band fluorescence emission of Tm3+ ions enhances significantly in the presence of Ag NPs with average diameter of ∼8 nm and local surface Plasmon resonance (LSPR) band of ∼590 nm, which is mainly attributed to the increased local electric field induced by Ag NPs at the proximity of doped rare-earth ions on the basis of energy transfer from Yb3+ to Tm3+ ions. An improvement by about 110% of fluorescence intensity is observed in the Tm3+/Yb3+ co-doped tellurite glass containing 0.5 mol% amount of AgNO3 while the prepared glass samples possess good thermal stability and amorphous structural nature. Meanwhile, the Judd-Ofelt intensity parameters Ωt (t = 2,4,6), spontaneous radiative transition probabilities, fluorescence branching ratios and radiative lifetimes of relevant excited levels of Tm3+ ions were determined based on the Judd-Ofelt theory to reveal the enhanced effects of Ag NPs on the 1.85 μm band spectroscopic properties, and the energy transfer micro-parameters and phonon contribution ratios were calculated based on the non-resonant energy transfer theory to elucidate the energy transfer mechanism between Yb3+ and Tm3+ ions. The present results indicate that the prepared Tm3+/Yb3+ co-doped tellurite glass with an appropriate amount of Ag NPs is a promising lasing media applied for 1.85 μm band solid-state lasers and amplifiers.

  10. High-power diode-side-pumped rod Tm:YAG laser at 2.07 μm.

    Science.gov (United States)

    Wang, Caili; Niu, Yanxiong; Du, Shifeng; Zhang, Chao; Wang, Zhichao; Li, Fangqin; Xu, Jialin; Bo, Yong; Peng, Qinjun; Cui, Dafu; Zhang, Jingyuan; Xu, Zuyan

    2013-11-01

    We report a high-power diode-laser (LD) side-pumped rod Tm:YAG laser of around 2 μm. The laser was water-cooled at 8°C and yielded a maximum output power of 267 W at 2.07 μm, which is the highest output power for an all solid-state cw 2.07 μm rod Tm:YAG laser reported as far as we know. The corresponding optical-optical conversion efficiency was 20.7%, and the slope efficiency was about 29.8%, respectively.

  11. Analysis of Eocene depositional environments - Preliminary TM and TIMS results, Wind River Basin, Wyoming

    Science.gov (United States)

    Stucky, Richard K.; Krishtalka, Leonard; Redline, Andrew D.; Lang, Harold R.

    1987-01-01

    Both Landsat TM and aircraft Thermal IR Multispectral Scanner (TIMS) data have been used to map the lithofacies of the Wind River Basin's Eocene physical and biological environments. Preliminary analyses of these data have furnished maps of a fault contact boundary and a complex network of fluvial ribbon channel sandstones. The synoptic view thereby emerging for Eocene fluvial facies clarifies the relationships of ribbon channel sandstones to fossil-bearing overbank/floodplain facies and certain peleosols. The utility of TM and TIMS data is thereby demonstrated.

  12. The Position of Aβ22-40 and Aβ1-42 in Anionic Lipid Membranes Containing Cholesterol.

    Science.gov (United States)

    Barrett, Matthew A; Alsop, Richard J; Hauß, Thomas; Rheinstädter, Maikel C

    2015-11-30

    Amyloid-β peptides interact with cell membranes in the human brain and are associated with neurodegenerative diseases, such as Alzheimer's disease. An emerging explanation of the molecular mechanism, which results in neurodegeneration, places the cause of neurotoxicity of the amyloid- peptides on their potentially negative interaction with neuronal membranes. It is known that amyloid-β peptides interact with the membrane, modifying the membrane's structural and dynamic properties. We present a series of X-ray diffraction experiments on anionic model lipid membranes containing various amounts of cholesterol. These experiments provide experimental evidence for an interaction of both the full length amyloid-β1-42 peptide, and the peptide fragment amyloid-β22-40 with anionic bilayer containing cholesterol. The location of the amyloid-β peptides was determined from these experiments, with the full length peptide embedding into the membrane, and the peptide fragment occupying 2 positions-on the membrane surface and embedded into the membrane core.

  13. 40 CFR 406.42 - Effluent limitations guidelines representing the degree of effluent reduction attainable by the...

    Science.gov (United States)

    2010-07-01

    ... technology currently available. 406.42 Section 406.42 Protection of Environment ENVIRONMENTAL PROTECTION... Milling Subcategory § 406.42 Effluent limitations guidelines representing the degree of effluent reduction...

  14. Bright white upconversion luminescence from Er3+/Tm3+/Yb3+-doped titanate-based glasses prepared by aerodynamic levitation method

    Science.gov (United States)

    Zhang, Minghui; Yu, Jianding; Jiang, Wan; Liu, Yan; Ai, Fei; Wen, Haiqin; Jiang, Meng; Yu, Huimei; Pan, Xiuhong; Tang, Meibo; Gai, Lijun

    2017-10-01

    Aerodynamic levitation method was employed to prepare Er3+/Tm3+/Yb3+-doped titanate-based glasses. DTA results show that the glass performs high thermal stability with the glass transition temperature of 799 °C. The interaction among rare earth ions has been discussed by adjusting the relative concentration. Er3+ ions can quench the upconversion luminescence of Tm3+ ions. Tm3+ ions play a strong role in quenching the emissions of Er3+ and Tm3+ when the content of Tm3+ ions is greater than or equal 0.05. From the view of the ratio of red emission to green emission, Tm3+ ions can improve the red emission of Er3+ ions to some extent in contrast with the green emissions of Er3+ ions. 980 nm incident laser can be efficiently absorbed by Yb3+ ions. The relative intensity of red, green, and blue upconversion luminescence has been tuned to obtain white light. The composition with white upconversion luminescence of the color coordinate (0.291, 0.3292) has been found. Moreover, white upconversion luminescence mechanism is a two-photon process of ET, ESA, and cooperative sensitization. Rare earth ions doped titanate-based glasses with bright upconversion luminescence perform potential applications in color display, back light, et al.

  15. Theoretical modelling of dual-wavelength pumped Yb3+–Tm3+ co-doped silica fibre laser

    International Nuclear Information System (INIS)

    Fu, Yuqing; Chen, Jianguo

    2010-01-01

    Numerical simulations have, for the first time to our knowledge, been carried out to characterize the Yb 3+ –Tm 3+ co-doped silica fibre laser (YTFL), defined by a fibre grating and an end mirror, by using the rate equations, which take into consideration both the energy transfer processes from Yb 3+ to Tm 3+ ions and the cross-relaxation processes among different Tm 3+ ions. A dual-wavelength pumping scheme with one at 805 nm and the other at 975 nm is used to pump the YTFL. We have investigated the wavelength-dependent output power of the YTFL, from 1750 to 2200 nm, which takes its maximum output power at ∼ 1800 nm. The effect of the cross-relaxation processes in the Tm 3+ -doped silica fibre laser has been studied. The results indicate that these processes are beneficial to the laser and should be considered in the theoretical modelling. The influence of the Yb 3+ concentration on the characteristics of the YTFL has also been analysed and the results show that Yb 3+ dopants can improve the output power and slope efficiency of the laser

  16. Pathogenetic justification of dietary supplement TestogenonTM for complex impact on men's reproductive system

    Directory of Open Access Journals (Sweden)

    V. G. Liflyandsky

    2015-01-01

    Full Text Available The reasonable complex preparation TestogenonTM for prevention and treatment of frustration of reproductive system of men including extracts of plants (bark of a pidzheum, a dioskorea, a yokhimba, a ginseng root and biologically active agents (L-arginin, vitamins C and E, B5, B6 and B12 is created pathogenetic. Harmlessness and safety of a preparation are confirmed in pilot studies. Preclinical researches of specific pharmacological activity of dietary supplement to food TestogenonTM, allowed to establish stimulation at experimental animals of production of own testosterone which concentration was authentically above, than at control animals. Besides, at the rats receiving TestogenonTM activation of all indicators of sexual behavior was observed: average frequency a cage on females was 82 % higher, the quantity of intromissiya exceeded that control animals at 12–15 times, the latent period a cage and an interval between sessions authentically decreased. The preparation is recommended for strengthening of a libido, increase in duration of sexual intercourse, elimination of erektilny dysfunction, simplification of age manifestations of a man's climax, and also within complex therapy of a good-quality hyperplasiya of a prostate gland, chronic not bacterial prostatitis, man's infertility, an incontience of urine, testosterone synthesis stimulation. TestogenonTM is contraindicated at the increased nervous excitability, sleeplessness, arterial hypertension, decrease in coagulability of blood, arrhythmia, the expressed dysfunction of a liver and kidneys. 

  17. Validation of the AmpFlSTR« SEfiler Plus(TM) PCR Amplification kit for forensic STR analysis

    DEFF Research Database (Denmark)

    Fredslund, Stine Frisk; Mogensen, Helle Smidt; Morling, Niels

    2009-01-01

    Validation of the AmpFlSTR« SEfiler Plus(TM) PCR Amplification kit with 29 and 30 PCR cycles for forensic STR analysis demonstrated that the kit had fewer artefacts than the AmpFlSTR« SGM Plus(TM) kit (28 PCR cycles). The SEfiler Plus kit was more sensitive and devoid of colour artefacts, but sho......, but showed more stutters, drop-ins, drop-outs and allelic imbalances...

  18. Modular to Monoblock: Difficulties of Detaching the M(2)a-Magnum(TM) Head Are Common in Metal-on-metal Revisions.

    Science.gov (United States)

    Mäntymäki, Heikki; Mäkelä, Keijo T; Vahlberg, Tero; Hirviniemi, Joni; Niinimäki, Tuukka

    2016-09-01

    Modern hip implants typically feature modular heads, which allow for easy exchange and removal from the femoral stem at the time of revision. However, owing to fretting, corrosion, or cold welding, the modular head may be difficult or impossible to separate from the underlying trunnion, especially if the implant has titanium interfaces between the head and the stem. We have repeatedly encountered difficulty removing the titanium sleeve adapter in the M(2)a-Magnum(TM) implant. Although the manufacturer warns about this complication and cases with these difficulties have been reported to the United States FDA, we believed this topic is important to study, because the frequency of difficulties in head removal is unknown and the complications related to this event have not been characterized. We asked: (1) Do revisions of M(2)a-Magnum(TM) implants differ from those of M(2)a-38(TM) implants in terms of ease of removal of the femoral head? (2) In cases where difficulty with M(2)a-Magnum(TM) head removal occurred, was the operative time, bleeding, risk of periprosthetic fracture, or joint infection increased compared with cases where the M(2)a-Magnum(TM) head was removed without difficulties? Between 2004 and 2014, we revised 296 THAs with metal-on-metal implants that involved M(2)a-Magnum(TM) (123) or M(2)a-38(TM) heads (88); of those, 84 were planned to include a femoral stem revision and insufficient data were available for three operations, so they were excluded from this analysis, leaving 124 THAs in the current retrospective study (70 THAs with M(2)a-Magnum(TM) and 54 THAs with M(2)a-38(TM) heads).The method of modular head removal, any difficulties removing the femoral head from the trunnion, operation time, and complications were recorded based on chart review. All the observed problems of detaching the head or taper adapter were among M(2)a-Magnum(TM) heads; there were no problems detaching the head in revisions of the M(2)a-38(TM) implant. In 29% (20 of 70) of

  19. Spectral characteristics and white emission of Dy{sup 3+}/Tm{sup 3+}-BaLaGa{sub 3}O{sub 7} phosphors

    Energy Technology Data Exchange (ETDEWEB)

    Gao, Shufang, E-mail: shfgao@yangtzeu.edu.cn [School of Physics and Optoelectronic Engineering, Yangtze University, Jingzhou 434023 (China); Xu, Shan [School of Physics and Optoelectronic Engineering, Yangtze University, Jingzhou 434023 (China); Wang, Yeqing [Department of Applied Physics, East China Jiaotong University, Nanchang, Jiangxi 330013 (China); Tu, Chaoyang, E-mail: tcy@fjirsm.ac.cn [Key Laboratory of Optoelectronic Materials Chemistry and Physics of CAS, Fujian Institute of Research on the Structure of Matter, CAS, Fuzhou, Fujian 350002 (China)

    2016-10-15

    Tm{sup 3+}-, Dy{sup 3+}-BaLaGa{sub 3}O{sub 7} phosphors have been synthesized by solid-phase sintering. X-ray diffraction (XRD) and photoluminescence properties of the phosphors were investigated in detail. The sample Tm{sup 3+} and Dy{sup 3+} ions co-doped BaLaGa{sub 3}O{sub 7} obtain white light emission by integrating a blue emission band located at 455 nm ({sup 1}D{sub 2}→{sup 3}F{sub 4}) and an orange one located at 573 nm ({sup 4}F{sub 9/2}→{sup 6}H{sub 13/2}) attributed to Tm{sup 3+} and Dy{sup 3+} ions, respectively. The study on the luminescence mechanism showed that there is the energy transfer between Tm{sup 3+} and Dy{sup 3+} in Tm{sup 3+}/Dy{sup 3+}-BaLaGa{sub 3}O{sub 7} phosphors.

  20. Normalization references for USEtoxTM-based toxic impact categories: North American and European economic systems

    DEFF Research Database (Denmark)

    Laurent, Alexis; Lautier, Anne; Rosenbaum, Ralph K.

    2011-01-01

    economic regions, North America and Europe, to calculate normalization references for the three currently-modelled USEtoxTM-based impact categories, i.e. freshwater ecotoxicity, human toxicity, divided into cancer effects and non-cancer effects. Base years for the references are 2004 for Europe and 2006...... coverage of organics in both the inventory and the CF databases. With respect to the intended global character of the USEtoxTM model, different approaches to determine normalization references of other economic systems (e.g. Asia or world) are discussed in relation to these findings. Overall, we thus...... recommend the use of the provided set of normalization references for USEtoxTM, but we also advocate 1) to perform an update as soon as a more comprehensive inventory can be obtained and as soon as characterization factors for metals are revised; 2) to consider extension to other economic systems in order...

  1. Comparison between refraction measured by Spot Vision ScreeningTM and subjective clinical refractometry

    Directory of Open Access Journals (Sweden)

    Daniela Lima de Jesus

    2016-02-01

    Full Text Available OBJECTIVE: The purpose of this study was to evaluate the accuracy of Spot Vision ScreeningTM as an autorefractor by comparing refraction measurements to subjective clinical refractometry results in children and adult patients. METHODS: One-hundred and thirty-four eyes of 134 patients were submitted to refractometry by Spot and clinical refractometry under cycloplegia. Patients, students, physicians, staff and children of staff from the Hospital das Clínicas (School of Medicine, University of São Paulo aged 7-50 years without signs of ocular disease were examined. Only right-eye refraction data were analyzed. The findings were converted in magnitude vectors for analysis. RESULTS: The difference between Spot Vision ScreeningTM and subjective clinical refractometry expressed in spherical equivalents was +0.66±0.56 diopters (D, +0.16±0.27 D for the vector projected on the 90 axis and +0.02±0.15 D for the oblique vector. CONCLUSIONS: Despite the statistical significance of the difference between the two methods, we consider the difference non-relevant in a clinical setting, supporting the use of Spot Vision ScreeningTM as an ancillary method for estimating refraction.

  2. Comparison between refraction measured by Spot Vision ScreeningTM and subjective clinical refractometry

    Science.gov (United States)

    de Jesus, Daniela Lima; Villela, Flávio Fernandes; Orlandin, Luis Fernando; Eiji, Fernando Naves; Dantas, Daniel Oliveira; Alves, Milton Ruiz

    2016-01-01

    OBJECTIVE: The purpose of this study was to evaluate the accuracy of Spot Vision ScreeningTM as an autorefractor by comparing refraction measurements to subjective clinical refractometry results in children and adult patients. METHODS: One-hundred and thirty-four eyes of 134 patients were submitted to refractometry by Spot and clinical refractometry under cycloplegia. Patients, students, physicians, staff and children of staff from the Hospital das Clínicas (School of Medicine, University of São Paulo) aged 7-50 years without signs of ocular disease were examined. Only right-eye refraction data were analyzed. The findings were converted in magnitude vectors for analysis. RESULTS: The difference between Spot Vision ScreeningTM and subjective clinical refractometry expressed in spherical equivalents was +0.66±0.56 diopters (D), +0.16±0.27 D for the vector projected on the 90 axis and +0.02±0.15 D for the oblique vector. CONCLUSIONS: Despite the statistical significance of the difference between the two methods, we consider the difference non-relevant in a clinical setting, supporting the use of Spot Vision ScreeningTM as an ancillary method for estimating refraction. PMID:26934234

  3. Removal of cadmium, copper, nickel, cobalt and mercury from water by Apatite II{sup TM}: Column experiments

    Energy Technology Data Exchange (ETDEWEB)

    Oliva, Josep [Department of Mining Engineering and Natural Resou-rces, Universitat Politecnica de Catalunya, Bases de Manresa 61-73, 08242 Manresa, Catalonia (Spain); De Pablo, Joan [Department of Chemical Engineering, Universitat Politecnica de Catalunya, Diagonal 647, 08028 Barcelona, Catalonia (Spain); Cortina, Jose-Luis, E-mail: jose.luis.cortina@upc.edu [Department of Chemical Engineering, Universitat Politecnica de Catalunya, Diagonal 647, 08028 Barcelona, Catalonia (Spain); Water Technology Center, CETaqua, Paseo de los Tilos 3, 08034 Barcelona, Catalonia (Spain); Cama, Jordi; Ayora, Carlos [Institute of Environmental Assessment and Water Research, IDAEA, CSIC, Jordi Girona 18, 08034 Barcelona, Catalonia (Spain)

    2011-10-30

    Highlights: {yields} The efficiency of Apatite II{sup TM} increases as the acidity decreases, then the application of apatite-based materials for metal removal treatments should be restricted to slightly acid to neutral waters. {yields} Because of the preferred process of using phosphate ions to form metal-phosphate precipitates, the mixture with other sources of alkalinity, such as limestone, is proposed to extend the duration of Apatite II{sup TM}. {yields} Compared with other reactive materials such as limestone and caustic magnesia that exhibit a reduction of porosity Apatite II{sup TM} showed stable hydraulic performance. {yields} The extrapolation of the column durabilities to a 1-m-thick passive treatment suggests that the Apatite II{sup TM} filling can be active between 5 and 10 years for an inflow pH exceeding 5. - Abstract: Apatite II{sup TM}, a biogenic hydroxyapatite, was evaluated as a reactive material for heavy metal (Cd, Cu, Co, Ni and Hg) removal in passive treatments. Apatite II{sup TM} reacts with acid water by releasing phosphates that increase the pH up to 6.5-7.5, complexing and inducing metals to precipitate as metal phosphates. The evolution of the solution concentration of calcium, phosphate and metals together with SEM-EDS and XRD examinations were used to identify the retention mechanisms. SEM observation shows low-crystalline precipitate layers composed of P, O and M. Only in the case of Hg and Co were small amounts of crystalline phases detected. Solubility data values were used to predict the measured column experiment values and to support the removal process based on the dissolution of hydroxyapatite, the formation of metal-phosphate species in solution and the precipitation of metal phosphate. Cd{sub 5}(PO{sub 4}){sub 3}OH(s), Cu{sub 2}(PO{sub 4})OH(s), Ni{sub 3}(PO{sub 4}){sub 2}(s), Co{sub 3}(PO{sub 4}){sub 2}8H{sub 2}O(s) and Hg{sub 3}(PO{sub 4}){sub 2}(s) are proposed as the possible mineral phases responsible for the removal

  4. [A study on the concentration quenching of Tm3+ upconversion luminescence].

    Science.gov (United States)

    Chen, B; Wang, H; Huang, S

    2001-06-01

    In this work, we have a designation and preparation of MFT glasses for upconversion, the glasses consisted of TeO2 and fluoride: PbF2, AlF3, BaF2, NaF and the impurity Tm2O3. In this glass system the oxide improve forming ability, the fluorides improve the microscopic environment around RE ions in glasses. In this glass host the content of Tm2O3 achieves to 4% mol and crystallization no occurred. A detail study on the concentration quenching of upconversion luminescence for 1G4-->3H6 and 1D2-->3H4 transitions was completed. The experimental results directed that the quenching concentration was 0.6 mol.% and higher 3 times than in other glasses materials. The cross relaxation and mechanism of concentration quenching were discussed.

  5. 45 CFR 305.42 - Penalty phase-in.

    Science.gov (United States)

    2010-10-01

    ... PROGRAM PERFORMANCE MEASURES, STANDARDS, FINANCIAL INCENTIVES, AND PENALTIES § 305.42 Penalty phase-in. States are subject to the performance penalties described in § 305.40 based on data reported for FY 2001. Data reported for FY 2000 will be used as a base year to determine improvements in performance during...

  6. Broadband ˜2μm emission in Tm3+/Ho3+ co-doped TeO2-WO3-La2O3 glass

    Science.gov (United States)

    Li, Kefeng; Wang, Guonian; Zhang, Junjie; Hu, Lili

    2010-10-01

    In this work, we report the infrared emission properties of Tm 3+/Ho 3+ co-doped TeO 2-WO 3-La 2O 3 (TWL) glass under 808 nm laser excitation. A broad and flat emission from 1600 to 2200 nm corresponding to the Tm 3+ ( 3F 4→ 3H 6) and Ho 3+ ( 5I 7→ 5I 8) emissions is observed. The full width at half maximum (FWHM) of this broadband increases up to a value of ˜370 nm with an optimal [Tm 3+]/[Ho 3+] concentration ratio. The energy transfer processes of Tm 3+↔Ho 3+ are analyzed and the results show that energy transfer between Tm 3+ and Ho 3+ plays an important role in the luminescence mechanism. The OH - influence on the broadband emission is also discussed. These results indicate that Tm 3+-Ho 3+ co-doped TWL glass could be a promising material for widely tunable laser or broadband amplifier applications.

  7. Diode-pumped Tm:YAP/YVO4 intracavity Raman laser

    International Nuclear Information System (INIS)

    Zhao, Jiaqun; Zhou, Xiaofeng; Wang, Guodong; Cheng, Ping; Xu, Feng

    2017-01-01

    The laser performance based on YVO 4 Raman conversion in a diode-pumped actively Q-switched Tm:YAP laser is demonstrated for the first time. With an incident diode power of 10.9 W and a pulse repetition rate of 1 kHz, the average output powers for the first Stokes laser at 2.4 μm is about 270 mW. (paper)

  8. Optical decoherence and persistent spectral hole burning in Tm3+:LiNbO3

    International Nuclear Information System (INIS)

    Thiel, C.W.; Sun, Y.; Boettger, T.; Babbitt, W.R.; Cone, R.L.

    2010-01-01

    We report studies of decoherence and spectral hole burning for the 794 nm optical transition of thulium-doped lithium niobate. In addition to transient spectral holes due to the 3 H 4 and 3 F 4 excited states of Tm 3+ , persistent spectral holes with lifetimes of up to minutes were observed when a magnetic field of a few hundred Gauss was applied. The observed anti-hole structure identified the hole burning mechanism as population storage in the 169 Tm nuclear hyperfine levels. In addition, the magnetic field was effective in suppressing spectral diffusion, increasing the phase memory lifetime from 11 μs at zero field to 23 μs in a field of 320 Gauss applied along the crystal's c-axis. Coupling between Tm 3+ and the 7 Li and 93 Nb spins in the host lattice was also observed and a quadrupole shift of 22 kHz was measured for 7 Li at 1.7 K. A Stark shift of 18 kHz cm/V was measured for the optical transition with the electric field applied parallel to the c-axis.

  9. Precise Plan in the analysis of volume precision in SynergyTM conebeam CT image

    International Nuclear Information System (INIS)

    Bai Sen; Xu Qingfeng; Zhong Renming; Jiang Xiaoqin; Jiang Qingfeng; Xu Feng

    2007-01-01

    Objective: A method of checking the volume precision in Synergy TM conebeam CT image. Methods: To scan known phantoms (big, middle, small spheres, cubes and cuniform cavum) at different positions (CBCT centre and departure centre from 5, 8, 10 cm along the accelerator G-T way)with conebeam CT, the phantom volume of reconstructed images were measure. Then to compared measured volume of Synergy TM conebeam CT with fanbeam CT results and nominal values. Results: The middle spheres had 1.5% discrepancy in nominal values and metrical average values at CBCT centre and departure from centre 5, 8 cm along accelerator G-T way. The small spheres showed 8.1%, with 0.8 % of the big cube and 2.9% of small cube, in nominal values and metrical average values at CBCT centre and departure from centre 5, 8, 10 cm along the accelerator G-T way. Conclusion: In valid scan range of Synergy TM conebeam CT, reconstructed precision is independent of the distance deviation from the center. (authors)

  10. Development of NutriSportEx TM -interactive sport nutrition based ...

    African Journals Online (AJOL)

    Development of NutriSportExTM-interactive sport nutrition based mobile application software. B.S. Pushpa, N.S. Safii, S.H. Hamzah, N Fauzi, W.K. Yeo, P.B. Koon, C.Y. Tsin, M.I. Mohamad, A.H.A. Rahman, C.L. Ming, R.A. Talib, M.R. Shahril ...

  11. IPR CATUARA TM – new cultivar of high gluten wheat

    Directory of Open Access Journals (Sweden)

    Carlos Roberto Riede

    2015-03-01

    Full Text Available The wheat cultivar IPR Catuara TM, obtained from a cross between the line LD 975 and the cultivar IPR 85, exhibits high gluten strength, which will allow the milling industry to supplement flours from wheats with weaker gluten strength, resulting in better quality products for the final consumer.

  12. Crystalline phase, profile characteristics and spectroscopic properties of Er{sup 3+}/Tm{sup 3+}-diffusion-codoped LiNbO{sub 3} crystal

    Energy Technology Data Exchange (ETDEWEB)

    Sun, Wen-Bao [Department of Opto-electronics and Information Engineering, School of Precision Instruments and Opto-electronics Engineering, Tianjin University, Tianjin 300072 (China); Key Laboratory of Optoelectronic Information Technology, Ministry of Education (Tianjin University), Tianjin 300072 (China); Zhang, Zi-Bo [Department of Engineering, Pierre and Marie Curie University (University of Paris VI), 4 place Jussieu, 75005 Paris (France); Sun, Hong-Xue [Department of Opto-electronics and Information Engineering, School of Precision Instruments and Opto-electronics Engineering, Tianjin University, Tianjin 300072 (China); Key Laboratory of Optoelectronic Information Technology, Ministry of Education (Tianjin University), Tianjin 300072 (China); Wong, Wing-Han, E-mail: eewhwong@cityu.edu.hk [Department of Opto-electronics and Information Engineering, School of Precision Instruments and Opto-electronics Engineering, Tianjin University, Tianjin 300072 (China); Key Laboratory of Optoelectronic Information Technology, Ministry of Education (Tianjin University), Tianjin 300072 (China); Department of Electronic Engineering and State Key Laboratory of Millimeter Waves, City University of Hong Kong, 83 Tat Chee Avenue, Kowloon, Hong Kong (China); Yu, Dao-Yin [Department of Opto-electronics and Information Engineering, School of Precision Instruments and Opto-electronics Engineering, Tianjin University, Tianjin 300072 (China); Key Laboratory of Optoelectronic Information Technology, Ministry of Education (Tianjin University), Tianjin 300072 (China); Pun, Edwin Yue-Bun [Department of Electronic Engineering and State Key Laboratory of Millimeter Waves, City University of Hong Kong, 83 Tat Chee Avenue, Kowloon, Hong Kong (China); and others

    2017-04-15

    Er{sup 3+}/Tm{sup 3+}-codoped LiNbO{sub 3} crystal was prepared by co-diffusion of stacked Er and Tm metal films coated onto surface of off-congruent, Li-deficient LiNbO{sub 3} substrate produced by Li-poor vapor transport equilibration technique. The crystalline phase on the diffused surface was analyzed by X-ray single-crystal diffraction. The Er{sup 3+} and Tm{sup 3+} profile characteristics were studied by secondary ion mass spectrometry. The emission spectra were measured under the 980 or 795 nm wavelength excitation, and the emission and absorption cross section spectra were calculated based upon McCumber theory. The lifetimes of some emissions were measured. The results show that the Er{sup 3+} and Tm{sup 3+} ions presence is in the form of LiNbO{sub 3} phase. Both ions obey to Gaussian profile with a diffusion depth 21.5 μm. In the codoping case, both ions keep their respective spectroscopic features of only doping case and do not affect each other. The codoping enables to combine the wavelength emissions of both ions and the resultant emission band in the telecommunication window around 1.5 μm is as wide as 150 nm, providing the possibility of S+C+L broadband amplification by employing commercial 980 and 795 nm laser diodes as the pump sources. The Er{sup 3+}/Tm{sup 3+}-codoped LN is a promising host material for integrated optics. - Graphical abstract: Er{sup 3+}/Tm{sup 3+}-codoped LiNbO{sub 3} crystal was prepared by co-diffusion of stacked Er and Tm metal films. The crystalline phase, diffusion profile and cross section spectra of Er{sup 3+} and Tm{sup 3+} ions in the diffusion layer have been investigated. The results show that the presence of Er{sup 3+} and Tm{sup 3+} ions is in the LiNbO{sub 3} phase. Both ions follow Gaussian profile with a diffusion depth 21.5 μm. Both ions keep their respective spectroscopic features of only doping case. Excited state absorption is the dominant process for 795-nm-upconvered fluorescence of Tm{sup 3+}. The

  13. Ultraviolet radiation monitoring in makkah city, Saudi Arabia, using thermoluminescence material CaF2:Tm

    International Nuclear Information System (INIS)

    Al-Ghorabie, F.H.; Natto, S.S.; AL-Lehyani, S.A.

    2005-01-01

    The aim of the present study is to explore the possibility of using Ca F2:Tm thermoluminescence material for measuring and monitoring of solar UV R in Makkah City, Saudi Arabia. Several laboratory experiments, prior to the field measurements, were performed included study of the effects of ultraviolet wavelengths on the response of the phosphor, study of the effect of increasing ultraviolet radiation dose on the intensity of thermoluminescence and study the effect of time factor on the thermoluminescence fading of Ca F 2 :Tm. The phosphor was then exposed directly for one hour to sunlight radiation on a daily basis for 90 days in an open field inside Umm Al-Qura university campus. The field measurements were performed during the months of June, July and August 2003 at 1:00 p.m. The laboratory and field results of this study showed that Ca F 2 :Tm can be used as a suitable dosimeter for solar UV R

  14. BOREAS RSS-15 SIR-C and Landsat TM Biomass and Landcover Maps of the NSA

    Science.gov (United States)

    Hall, Forrest G. (Editor); Nickeson, Jaime (Editor); Ranson, K. Jon

    2000-01-01

    As part of BOREAS, the RSS-15 team conducted an investigation using SIR-C, X-SAR, and Landsat TM data for estimating total above-ground dry biomass for the SSA and NSA modeling grids and component biomass for the SSA. Relationships of backscatter to total biomass and total biomass to foliage, branch, and bole biomass were used to estimate biomass density across the landscape. The procedure involved image classification with SAR and Landsat TM data and development of simple mapping techniques using combinations of SAR channels. For the SSA, the SIR-C data used were acquired on 06-Oct-1994, and the Landsat TM data used were acquired on 02-Sep-1995. The maps of the NSA were developed from SIR-C data acquired on 13-Apr-1994. The data files are available on a CD-ROM (see document number 20010000884), or from the Oak Ridge National Laboratory (ORNL) Distributed Active Archive Center (DAAC).

  15. Landsat 5 TM images and DEM in lithologic mapping of Payen Volcanic Field (Mendoza Province, Argentina)

    International Nuclear Information System (INIS)

    Fornaciai, A.; Bisson, M.; Mazzarini, F.; Del Carlo, P.; Pasquare, G.

    2009-01-01

    Satellite image such as Landsat 5 TM scene provides excellent representation of Earth and synoptic view of large geographic areas in different band combination. Landsat TM images allow automatic and semi-automatic classification of land cover, nevertheless the software frequently may some difficulties in distinguishing between similar radiometric surfaces. In this case, the use of Digital Elevation Model (DEM) can be an important tool to identify different surface covers. In this study, several False Color Composite (FCC) of Landsat 5 TM Image, DEM and the respective draped image of them, were used to delineate lithological boundaries and tectonic features of regional significance of the Paven Volcanic Field (PVF). PFV is a Quaternary fissural structure belonging to the black-arc extensional areas of the Andes in the Mendoza Province (Argentina) characterized by many composite basaltic lava flow fields. The necessity to identify different lava flows with the same composition, and then with same spectral features, allows to highlight the improvement of synergic use of TM images and shaded DEM in the visual interpretation. Information obtained from Satellite data and DEM have been compared with previous geological maps and transferred into a topographical base map. Based on these data a new lithological map at 1:100.000 scale has been presented [it

  16. First-principles calculations of the structural and thermodynamic properties of bcc, fcc and hcp solid solutions in the Al-TM (TM = Ti, Zr and Hf) systems: A comparison of cluster expansion and supercell methods

    International Nuclear Information System (INIS)

    Ghosh, G.; Walle, A. van de; Asta, M.

    2008-01-01

    The thermodynamic properties of solid solutions with body-centered cubic (bcc), face-centered cubic (fcc) and hexagonal close-packed (hcp) structures in the Al-TM (TM = Ti, Zr and Hf) systems are calculated from first-principles using cluster expansion (CE), Monte-Carlo simulation and supercell methods. The 32-atom special quasirandom structure (SQS) supercells are employed to compute properties at 25, 50 and 75 at.% TM compositions, and 64-atom supercells have been employed to compute properties of alloys in the dilute concentration limit (one solute and 63 solvent atoms). In general, the energy of mixing (Δ m E) calculated by CE and dilute supercells agree very well. In the concentrated region, the Δ m E values calculated by CE and SQS methods also agree well in many cases; however, noteworthy discrepancies are found in some cases, which we argue originate from inherent elastic and dynamic instabilities of the relevant parent lattice structures. The importance of short-range order on the calculated values of Δ m E for hcp Al-Ti alloys is demonstrated. We also present calculated results for the composition dependence of the atomic volumes in random solid solutions with bcc, fcc and hcp structures. The properties of solid solutions reported here may be integrated within the CALPHAD formalism to develop reliable thermodynamic databases in order to facilitate: (i) calculations of stable and metastable phase diagrams of binary and multicomponent systems, (ii) alloy design, and (iii) processing of Al-TM-based alloys

  17. A MultiSite GatewayTM vector set for the functional analysis of genes in the model Saccharomyces cerevisiae

    Directory of Open Access Journals (Sweden)

    Nagels Durand Astrid

    2012-09-01

    Full Text Available Abstract Background Recombinatorial cloning using the GatewayTM technology has been the method of choice for high-throughput omics projects, resulting in the availability of entire ORFeomes in GatewayTM compatible vectors. The MultiSite GatewayTM system allows combining multiple genetic fragments such as promoter, ORF and epitope tag in one single reaction. To date, this technology has not been accessible in the yeast Saccharomyces cerevisiae, one of the most widely used experimental systems in molecular biology, due to the lack of appropriate destination vectors. Results Here, we present a set of three-fragment MultiSite GatewayTM destination vectors that have been developed for gene expression in S. cerevisiae and that allow the assembly of any promoter, open reading frame, epitope tag arrangement in combination with any of four auxotrophic markers and three distinct replication mechanisms. As an example of its applicability, we used yeast three-hybrid to provide evidence for the assembly of a ternary complex of plant proteins involved in jasmonate signalling and consisting of the JAZ, NINJA and TOPLESS proteins. Conclusion Our vectors make MultiSite GatewayTM cloning accessible in S. cerevisiae and implement a fast and versatile cloning method for the high-throughput functional analysis of (heterologous proteins in one of the most widely used model organisms for molecular biology research.

  18. Spectroscopic investigations of OH- influence on near-infrared fluorescence quenching of Yb3+/Tm3+ co-doped sodium-metaphosphate glasses

    International Nuclear Information System (INIS)

    Terra, I.A.A.; Camargo, A.S.S. de; Terrile, M.C.; Nunes, L.A.O.

    2008-01-01

    Energy transfer processes were studied in two sets of Yb 3+ and Tm 3+ co-doped sodium-metaphosphate glasses, prepared in air and nitrogen atmospheres. Using Foerster, Dexter, and Miyakawa theoretical models, the energy transfer parameters were calculated. The main ion-ion energy transfer processes analyzed were energy migration among Yb 3+ ions, cross-relaxations between Yb 3+ and Tm 3+ ions, and interactions with OH - radicals. The results indicated that Yb→Tm energy transfer favors 1.8 μm emissions, and there is no evidence of concentration quenching up to 2% Tm 2 O 3 doping. As expected, samples prepared in nitrogen atmosphere present higher fluorescence quantum efficiency than those prepared in air, and this feature is specially noted in the near-infrared region, where the interaction with the OH - radicals is more pronounced

  19. Energy transfer and 2.0 μm emission in Tm{sup 3+}/Ho{sup 3+} co-doped α-NaYF{sub 4} single crystals

    Energy Technology Data Exchange (ETDEWEB)

    Feng, Zhigang; Yang, Shuo [Key laboratory of Photo-electronic Materials, Ningbo University, Ningbo, Zhejiang 315211 (China); Xia, Haiping, E-mail: hpxcm@nbu.edu.cn [Key laboratory of Photo-electronic Materials, Ningbo University, Ningbo, Zhejiang 315211 (China); Wang, Cheng; Jiang, Dongsheng; Zhang, Jian; Gu, Xuemei; Zhang, Yuepin [Key laboratory of Photo-electronic Materials, Ningbo University, Ningbo, Zhejiang 315211 (China); Chen, Baojiu, E-mail: bjchen@dlmu.edu.cn [Department of Physics, Dalian Maritime University, Dalian, Liaoning Province 116026 (China); Jiang, Haochuan [Ningbo Institute of Materials Technology and Engineering, the Chinese Academy of Sciences, Ningbo, Zhejiang 315211 (China)

    2016-04-15

    Highlights: • Cubic NaYF{sub 4} single crystals co-doped with ∼1.90 mol% Tm{sup 3+} and various Ho{sup 3+} concentrations were grown by Bridgman method. • The maximum fluorescence lifetime was 23.23 ms for Tm{sup 3+} (1.90 mol%)/Ho{sup 3+} (3.89 mol%) co-doped α-NaYF{sub 4}. • The obtained energy transfer rate (W{sub ET}) and energy transfer efficiency (η) of Tm{sup 3+}:{sup 3}F{sub 4} are 1077 s{sup −1} and 95.0%, respectively. • The maximum emission cross section reached 1.06 × 10{sup −20} cm{sup 2}. - Abstract: Cubic NaYF{sub 4} single crystals co-doped with ∼1.90 mol% Tm{sup 3+} and various Ho{sup 3+} concentrations were grown by Bridgman method. The energy transfer from Tm{sup 3+} to Ho{sup 3+} and the optimum fluorescence emission around 2.04 μm of Ho{sup 3+} ion were investigated based on the measured absorption spectra, emission spectra, emission cross section and decay curves under excitation of 800 nm LD. The emission intensity at 2.04 μm increased with the increase of Ho{sup 3+} concentration from 0.96 mol% to 3.89 mol% when the concentration of Tm{sup 3+} was held constantly at ∼1.90 mol%. Moreover, the maximum emission cross section reached 1.06 × 10{sup −20} cm{sup 2} and the maximum fluorescence lifetime was 23.23 ms for Tm{sup 3+}(1.90 mol%)/Ho{sup 3+}(3.89 mol%) co-doped one. According to the measured lifetime of Tm{sup 3+} single-doped and Tm{sup 3+}/Ho{sup 3+} co-doped samples, the maximum energy transfer efficiency of Tm{sup 3+}:{sup 3}F{sub 4} level was 95.0%. Analysis on the fluorescence dynamics indicated that electric dipole–dipole is dominant for the energy transfer from Tm{sup 3+} to Ho{sup 3+}.

  20. Phase Diagram of Binary Mixture E7:TM74A Liquid Crystals

    Directory of Open Access Journals (Sweden)

    Serafin Delica

    1999-12-01

    Full Text Available Although there are many liquid crystalline materials, difficulty is often experienced in obtaining LCs that are stable and has a wide mesophase range. In this study, mixtures of two different LCs were used to formulate a technologically viable LC operating at room temperature. Nematic E7(BDH and cholesteric TM74A were mixed at different weight ratios at 10% increments. Transition temperatures were determined via Differential Scanning Calorimetry and phase identification was done using Optical Polarizing Microscopy. The phase diagram showed the existence of three different phases for the temperature range of 10-80°C. Mixtures with 0-20% E7 exhibit only the cholesteric-nematic mesophase, which could be due to the mixture's being largely TM74A and its behavior in the temperature range considered is similar to the behavior of pure TM74A. With an increase in the concentration of E7, the smectic phase of the pure cholesteric was enhanced, as seen from the increased transition to the cholesteric-nematic phase and a broader smectic range. The cholesteric-nematic to isotropic transition increased as the nematic concentration increases, following the behavior expected from LC mixtures. For mixtures that are largely nematic (more than 50% E7, the smectic phase has vanished and the cholesteric-nematic phase dominated from 30-60°C.

  1. 40 CFR 424.42 - Effluent limitations guidelines representing the degree of effluent reduction attainable by the...

    Science.gov (United States)

    2010-07-01

    ... technology currently available. 424.42 Section 424.42 Protection of Environment ENVIRONMENTAL PROTECTION... Covered Calcium Carbide Furnaces With Wet Air Pollution Control Devices Subcategory § 424.42 Effluent... practicable control technology currently available. Except as provided in §§ 125.30 through 125.32, and...

  2. TM grating coupler on low-loss LPCVD based Si3N4 waveguide platform

    Science.gov (United States)

    Dabos, G.; Manolis, A.; Giesecke, A. L.; Porschatis, C.; Chmielak, B.; Wahlbrink, T.; Pleros, N.; Tsiokos, D.

    2017-12-01

    We demonstrate, for the first time to our knowledge, a fully etched TM grating coupler for low-loss Low-Pressure-Chemical-Vapor-Deposition (LPCVD) based silicon nitride platform with a coupling loss of 6.5 dB at 1541 nm and a 1 dB bandwidth of 55 nm, addressing applications where TM polarization is a pre-requisite. The proposed GC and the 360 nm × 800 nm strip based Si3N4 waveguides have been fabricated by optical projection lithography using an i-line stepper tool enabling low-cost and mass manufacturing of photonic-integrated-circuits.

  3. Spectral intensities for stoichiometric elpasolites. I. Absorption and emission of Tm+3 in systems of the Cs2NaTmZ6 type

    International Nuclear Information System (INIS)

    Acevedo, R; Poblete, V; Pozo, J; Elgueta, R; Tanner, P.A

    2000-01-01

    Based upon new experimental data for systems such as, Cs 2 NaTmZ 6 , where Z - =Cl - , F - [1-4], we have carried out a thorough study of the mechanistic factors related with the spectral intensities for both the absorptions and the emissions of the Cs 2 NaTmZ 6 system. For the above purposes, we have generalized our previous calculation models, and in this article we show novel results for the emissions 3 H 4 (Γ i )→ 3 F 4 (Γ j ) and for the absorptions 3 H 6 (A 1 )→ 3 F 4 (Γ i ), 1 G 4 (Γ i ), 3 H 5 (Γ i ), with Γ-k(k=i,j)=A 1 ,E,T 1 ,T 2 and Γ 1 =T a 1 , T b 1 , E, T 2 . The effects due to dispersion (essentially, electrostatic in character), details of the short range vibrational force field and Jahn-Teller distortion are discussed in the text. The agreement among experiment and theory is satisfactory and a generalized model with a few number of adjustable parameters is introduced to account for the observed spectral intensities

  4. Pharmacological Modulation of AMPAR Rescues Intellectual Disability-Like Phenotype in Tm4sf2−/y Mice

    KAUST Repository

    Murru, Luca

    2017-08-02

    Intellectual disability affects 2–3% of the world’s population and typically begins during childhood, causing impairments in social skills and cognitive abilities. Mutations in the TM4SF2 gene, which encodes the TSPAN7 protein, cause a severe form of intellectual disability, and currently, no therapy is able to ameliorate this cognitive impairment. We previously reported that, in cultured neurons, shRNA-mediated down-regulation of TSPAN7 affects AMPAR trafficking by enhancing PICK1–GluA2 interaction, thereby increasing the intracellular retention of AMPAR. Here, we found that loss of TSPAN7 function in mice causes alterations in hippocampal excitatory synapse structure and functionality as well as cognitive impairment. These changes occurred along with alterations in AMPAR expression levels. We also found that interfering with PICK1–GluA2 binding restored synaptic function in Tm4sf2−/y mice. Moreover, potentiation of AMPAR activity via the administration of the ampakine CX516 reverted the neurological phenotype observed in Tm4sf2−/y mice, suggesting that pharmacological modulation of AMPAR may represent a new approach for treating patients affected by TM4SF2 mutations and intellectual disability.

  5. Scaling relations for a beam-deflecting TM110 mode in an asymmetric cavity

    International Nuclear Information System (INIS)

    Takeda, H.

    1989-01-01

    A deflecting mode in an rf cavity caused by an aperture of the coupling hole from a waveguide is studied. If the coupling hole was a finite size, the rf modes in the cavity can be distorted. We consider the distorted mode as a sum of the accelerating mode, and the deflecting mode. The finite-size coupling hole can be considered as radiating dipole sources in a closed cavity. Following the prescription given by H. Bethe, the relative strength of the deflecting mode TM 110 to the accelerating TM 010 mode is calculated by decomposing the dipole source field into cavity eigenmodes. Scaling relations are obtained as a function of the coupling hole radius. 2 refs., 6 figs

  6. Micro-Fuel Cells{sup TM} for portable electronics

    Energy Technology Data Exchange (ETDEWEB)

    Hockaday, R.G.; DeJohn, M.; Navas, C.; Turner, P.S.; Vaz, H.L.; Vazul, L.L. [Energy Related Devices Inc., Los Alamos, NM (United States)

    2000-05-01

    The Micro-Fuel Cell{sup TM} is a new power supply which provides a superior alternative compared to rechargeable batteries. A prototype has been developed by Manhattan Scientifics Inc. in collaboration with Energy Related Devices Inc. This mass-producible high-energy power supply can be used for cellular telephones, portable computers and other portable devices. Instead of being recharged, it can be easily refueled with methanol. The approach taken in designing this product was to develop a competitive product with definite advantages over existing products. The Micro-Fuel Cell{sup TM} is based on the idea that a fuel cell can be built onto an engineered microplastic substrate. In this case, the integrated design makes use of thin film vacuum deposition techniques to coat patterned, etched-nuclear-particle-track plastic membranes. This process forms catalytically active surface area electrodes on either side of a single structured proton-exchange-membrane electrolyte. Methanol was the choice fuel for this system because compared to hydrogen and metal hydrides, it was considered to be safer and more compact. In addition, the theoretical specific energy of methanol is significantly higher than for lithium-ion batteries. The problem of crossover, whereby methanol fuel diffuses across the fuel cell from the anode to the cathode, has also been solved by using a selectively permeable membrane. 5 refs., 4 figs.

  7. TmSR-C, scavenger receptor class C, plays a pivotal role in antifungal and antibacterial immunity in the coleopteran insect Tenebrio molitor.

    Science.gov (United States)

    Kim, Soo Gon; Jo, Yong Hun; Seong, Jeong Hwan; Park, Ki Beom; Noh, Mi Young; Cho, Jun Ho; Ko, Hye Jin; Kim, Chang Eun; Tindwa, Hamisi; Patnaik, Bharat Bhusan; Bang, In Seok; Lee, Yong Seok; Han, Yeon Soo

    2017-10-01

    Scavenger receptors (SRs) constitute a family of membrane-bound receptors that bind to multiple ligands. The SR family of proteins is involved in removing cellular debris, oxidized low-density lipoproteins, and pathogens. Specifically, class C scavenger receptors (SR-C) have also been reported to be involved in phagocytosis of gram-positive and -negative bacteria in Drosophila and viruses in shrimp. However, reports are unavailable regarding the role of SR-C in antifungal immune mechanisms in insects. In this study, a full-length Tenebrio molitor SR-C (TmSR-C) sequence was obtained by 5'- and 3'-Rapid amplification of cDNA ends-polymerase chain reaction (RACE-PCR). The TmSR-C full-length cDNA comprised 1671 bp with 5'- and 3'-untranslated regions of 23- and 107-bp, respectively. TmSR-C encodes a putative protein of 556 amino acid residues that is constitutively expressed in all tissues of late instar larvae and 2-day-old adults, with the highest transcript levels observed in hemocytes of larvae and adults. TmSR-C mRNA showed a 2.5-fold and 3-fold increase at 24 and 6 h after infection with Candida albicans and β-glucan, respectively. Immunoassay with TmSR-C polyclonal antibody showed induction of the putative protein in the cytosols of hemocytes at 3 h after inoculation of C. albicans. RNA interference (RNAi)-based gene silencing and phagocytosis assays were used to understand the role of TmSR-C in antifungal immunity. Silencing of TmSR-C transcripts reduced the survivability of late instar larvae at 2 days post-inoculation of C. albicans, Escherichia coli, or Staphylococcus aureus. Furthermore, in TmSR-C-silenced larvae, there was a decline in the rate of microorganism phagocytosis. Taken together, results of this study suggest that TmSR-C plays a pivotal role in phagocytosing not only fungi but also gram-negative and -positive bacteria in T. molitor. Copyright © 2017. Published by Elsevier Ltd.

  8. Efficient high power 2 micron Tm3+-Doped Fiber Laser, Phase I

    Data.gov (United States)

    National Aeronautics and Space Administration — This proposal is for the development of new Tm3+ doped germanate glass fibers for efficient high power 2 micron fiber lasers capable of generating an output power of...

  9. Essentials of MMPI-A[TM] Assessment. Essentials of Psychological Assessment Series.

    Science.gov (United States)

    Archer, Robert P.; Krishnamurthy, Radhika

    This book is designed to provide fundamental information concerning the procedures necessary to administer, score, interpret, and report findings from the Minnesota Multiphasic Personality Inventory-Adolescent[TM] (MMPI-A), the most widely used objective personality assessment instrument for adolescents. The chapters are: (1) "Overview";…

  10. Evaluation of Some (n,n'), (n,γ), (n,p), (n,2n) and (n,3n) Reaction Excitation Functions for Fission and Fusion Reactor Dosimetry Applications; Evaluation of the Excitation Functions for the 54Fe(n,p)54Mn, 58Ni(n,2n)57Ni, 67Zn(n,p)67Cu, 92Mo(n,p)92mNb, 93Nb(n,γ)94Nb, 113In(n,n')113mIn, 115In(n,γ) 116mIn, and 169Tm(n,3n)167Tm Reactions. Progress Report on Research Contract No 16242

    International Nuclear Information System (INIS)

    Zolotarev, K.I.; Zolotarev, P.K.

    2013-12-01

    Cross section data for the 54 Fe(n,p) 54 Mn, 58 Ni(n,2n) 57 Ni, 67 Zn(n,p) 67 Cu, 92 Mo(n,p) 92m Nb, 93 Nb(n,γ) 94 Nb, 113 In(n,n') 113m In, 115 In(n,γ) 116m In, 169 Tm(n,3n) 167 Tm reactions are needed to solve a wide spectrum of scientific and technical tasks. Activation detectors based on these reactions may be used in the field of reactor dosimetry. Furthermore, the 54 Fe(n,p) 54 Mn reaction is often used in experimental nuclear physics as a monitor reaction for measurements of unknown cross sections by means of the activation method over the neutron energy range from 5 to 15 MeV. The 93 Nb(n,γ) 94 Nb reaction is also very promising for using in retrospective neutron dosimetry for determination of total neutron fluence during a campaign of a reactor. In the existing version of the International Reactor Dosimetry File and the new extended version named as IRDFF data for excitation functions of 67 Zn(n,p) 67 Cu, 92 Mo(n,p) 92m Nb, 113 In(n,n') 113m In, and 169 Tm(n,3n) 167 Tm reactions are absent. Data for these reactions are also absent in the JENDL/D-99 dosimetry file. Excitation functions of 67 Zn(n,p) 67 Cu and 169 Tm(n,3n) 167 Tm are presented in the TENDL-2012, EAF-2010, JENDL-4.0, JEFF-3.1/A, MENDL-2 libraries. Cross section data for the 67 Zn(n,p) 67 Cu reaction up to 20 MeV are given also in the JENDL/HE-2007 library. Excitation functions of the 92 Mo(n,p) 92m Nb and 113 In(n,n') 113m In reactions are evaluated in the EAF-2010 and JEFF-3.1/A libraries. Cross section data for the 113 In(n,n') 113m In reaction are given also in the TENDL-2010 library. It is necessary to note that neutron data in the JEFF-3.1/A and JENDL-4.0 libraries were evaluated up to 20 MeV. Neutron data in the TENDL-2012, EAF-2010, MENDL-2 and TENDL-2010 libraries had been evaluated up to 30 MeV, 60 MeV, 100 MeV and 200 MeV, respectively. Neutron cross sections in the MENDL-2, TENDL-2010 and TENDL-2012 libraries had been obtained on the basis of pure theoretical model calculations

  11. Empty 4f states in TmS

    International Nuclear Information System (INIS)

    Wachter, P.; Grioni, M.

    1998-01-01

    The reflectivity of TmS single crystals has been measured between 2 meV and 12 eV at room temperature and at 6 K. Besides 3p 6 -5d interband transitions a plasma edge due to free carriers is observed. In the middle infrared (near 50 meV) two sharp lines are found which are interpreted as transitions from the Fermi level into empty crystal field split 4f 13 states. A Bremsstrahlen isochromat spectroscopy (BIS) measurement supports the assumption that the empty 4f 13 state is close to the Fermi energy. (orig.)

  12. Judd–Ofelt analysis of spectra and experimental evaluation of laser performance of Tm3+ doped Lu2SiO5 crystal

    International Nuclear Information System (INIS)

    Yao Baoquan; Zheng Liangliang; Duan Xiaoming; Zhao Guangjun; Zong Yanhua

    2008-01-01

    This paper reports that the Tm 3+ :Lu 2 SiO 5 (Tm:LSO) crystal is grown by Czochralski technique. The room-temperature absorption spectra of Tm:LSO crystal are measured on a b-cut sample with 4 at.% thulium. According to the obtained Judd–Ofelt intensity parameters Ω 2 = 9.3155 × 10 −20 cm 2 , Ω 4 = 8.4103 × 10 −20 cm 2 ,Ω 6 = 1.5908 × 10 −20 cm 2 , the fluorescence lifetime is calculated to be 2.03 ms for 3 F 4 → 3 H 6 transition, and the integrated emission cross section is 5.81 × 10 −18 cm 2 . Room-temperature laser action near 2μm under diode pumping is experimentally evaluated in Tm:LSO. An optical-optical conversion efficiency of 9.1% and a slope efficiency of 16.2% are obtained with continuous-wave maximum output power of 0.67 W. The emission wavelengths of Tm:LSO laser are centred around 2.06 μm with spectral bandwidth of ∼13.6 nm. (nuclear physics)

  13. Fretting wear damage of HexTOOL{sup TM} composite depending on the different fibre orientations

    Energy Technology Data Exchange (ETDEWEB)

    Terekhina, S; Salvia, M; Fouvry, S [Laboratoire de Tribologie et Dynamique des Systemes, UMR CNRS ECL ENISE ENSMSE 5513, Ecole Centrale de Lyon, 69134 Ecully cedex (France); Malysheva, G; Tarasova, T, E-mail: svetlana.terekhina@ec-lyon.fr, E-mail: svetlanaterekhina@yandex.ru [Bauman Moscow State Technical University, 105005 Moscow, 5, 2nd Baumanskaya str (Russian Federation)

    2009-09-15

    The composites have drawn considerable interest in the mould processes. The vibrations and fatigue stresses induced in the moulds made evident to characterize the composite HexTOOL{sup TM} under fretting conditions. Fretting is a small-amplitude oscillatory motion between contacting surfaces. The running conditions fretting maps (RCFM) of composite at ambient conditions were established. The influence of different fiber orientations of HexTOOL{sup TM} composite on the wear kinetics was shown. An energy wear approach was developed. According to results of dynamic mechanical analysis (DMA), the viscoelastic properties of composite material were obtained.

  14. Factors influencing the temporal growth rate of the high order TM{sub 0n} modes in the Ka-band overmoded Cherenkov oscillator

    Energy Technology Data Exchange (ETDEWEB)

    Wu, Dapeng, E-mail: vipbenjamin@163.com; Shu, Ting; Ju, Jinchuan [College of Photoelectric Science and Engineering, National University of Defense Technology, Changsha 410073 (China)

    2015-06-15

    When the wavelength of overmoded Cherenkov oscillator goes into Ka-band, power handling capacity becomes an essential issue. Using the TM{sub 02} mode or higher order TM{sub 0n} modes as the operating mode is a potential solution. This paper is aimed to find some proper parameters to make the temporal growth rate of the TM{sub 02} mode higher in our previously studied Gigawatt (GW)-class Ka band oscillator. An accurate and fast calculation method of the “hot” dispersion equation is derived for rectangular corrugated SWSs, which are widely used in the high frequency Cherenkov devices. Then, factors that affect the temporal growth rate of the high order TM{sub 0n} modes are analyzed, including the depth of corrugation, the radius of drift tube, and the diode voltage. Results show that, when parameters are chosen properly, the temporal growth rate of the TM{sub 02} mode can be as high as 0.3 ns{sup −1}.

  15. Comparison of the safety and efficacy for application of (cypher)TM and (taxus)TM coronary stent in patients with coronary heart disease and concurrent diabetic

    International Nuclear Information System (INIS)

    Zhang Junjie; Chen Shaoliang; Chen Huaixin; Li Zhiheng; Lin Yanting

    2005-01-01

    Objective: To compare the relative safety and efficacy of Cypher and Taxus stent in coronary heart disease complicated with diabetes. Methods: A retrospective study of our hospital's Cardiology database containing one hundred and twenty-two CHD complicated with diabetes undergone selective or urgent implantation of DES stent between June 2002 and February 2004 were divided into Cypher stent group (n=31) and Taxus stent group (n=91). The endpoints included cardiac death ,myocardial infarction (MI) and TLR at 6-month. Results: 122 patients with majority of males (80%) and mean age of 56 ± 11 years. The baseline characteristics were similar in both groups. Majority lesions treated were consisted of AHA/ACC Type B2/C (75%). Compared to the Taxus group, the Cypher group had a smaller mean reference diameter (2.4±0.6 mm versus 2.6±0.7 mm, P TM and (Taxus) TM coronary stents are proved to be equally safe and effective with low rate of clinical restenosis, TLR and MACE at 6-month in coronary heart disease complicated with diabetes patients. (authors)

  16. TmCactin plays an important role in Gram-negative and -positive bacterial infection by regulating expression of 7 AMP genes in Tenebrio molitor

    Science.gov (United States)

    Jo, Yong Hun; Jung Kim, Yu; Beom Park, Ki; Hwan Seong, Jeong; Gon Kim, Soo; Park, Soyi; Young Noh, Mi; Seok Lee, Yong; Soo Han, Yeon

    2017-01-01

    Cactin was originally identified as an interactor of the Drosophila IκB factor Cactus and shown to play a role in controlling embryonic polarity and regulating the NF-κB signaling pathway. While subsequent studies have identified the roles for Cactin in the mammalian immune response, the immune function of Cactin in insects has not been described yet. Here, we identified a Cactin gene from the mealworm beetle, Tenebrio molitor (TmCactin) and characterized its functional role in innate immunity. TmCactin was highly expressed in prepupa to last instar stages, and its expression was high in the integument and Malpighian tubules of last instar larvae and adults. TmCactin was induced in larvae after infection with different pathogens and detectable within 3 hours of infection. The highest levels of TmCactin expression were detected at 9 hours post infection. TmCactin RNAi significantly decreased the survival rates of larvae after challenge with Escherichia coli and Staphylococcus aureus, but had no significant effect after challenge with Candida albicans. Furthermore, TmCactin RNAi significantly reduced the expression of seven antimicrobial peptide genes (AMPs) after bacterial challenge. Our results suggest that TmCactin may serve as an important regulator of innate immunity, mediating AMP responses against both Gram-positive and Gram-negative bacteria in T. molitor. PMID:28418029

  17. Using National Instruments LabVIEW[TM] Education Edition in Schools

    Science.gov (United States)

    Butlin, Chris A.

    2011-01-01

    With the development of LabVIEW[TM] Education Edition schools can now provide experience of using this widely used software. Here, a few of the many applications that students aged around 11 years and over could develop are outlined in the resulting front panel screen displays and block diagrams showing the associated graphical programmes, plus a…

  18. Optical absorption and gamma-radiation-shielding parameter studies of Tm3+-doped multicomponent borosilicate glasses

    Science.gov (United States)

    Lakshminarayana, G.; Sayyed, M. I.; Baki, S. O.; Lira, A.; Dong, M. G.; Kaky, Kawa M.; Kityk, I. V.; Mahdi, M. A.

    2018-05-01

    Different concentrations (0.1‒2.0 mol%) of Tm3+-doped multicomponent borosilicate glasses with 10 mol% Li2O (alkali) or MgO (alkaline) have been synthesized and their optical absorption and radiation shielding features were studied. For both Li2O and MgO series 0.5 mol% Tm3+-doped glass samples, the evaluated Ωλ ( λ = 2, 4, and 6) Judd-Ofelt (JO) intensity parameters from experimental oscillator strengths were used in estimating the radiative transition probabilities ( A R), branching ratios ( β R), and radiative lifetimes ( τ R) for several emission transitions. Using the XCOM software, the mass attenuation coefficients ( µ/ ρ) for all the fabricated glasses were evaluated within the 0.015‒10 MeV energy range. Also, the ( µ/ ρ) values were calculated at 0.356, 0.662, 1.173, and 1.33 MeV photon energies by MCNP5 simulation code and the results were compared with those obtained by XCOM. The ( µ/ ρ) values for Li2O, as well as MgO series glasses, increase with the addition of Tm2O3 and these values for MgO series glasses are slightly higher with respect to Li2O series glasses. From the ( µ/ ρ) values, effective atomic number ( Z eff), half-value layer (HVL), and mean free path (MFP) were calculated and the HVL and MFP results revealed that high-energy photons have more penetration into a glass sample compared to low-energy photons. Further, geometric progression (GP) fitting method was utilized to calculate the exposure buildup factor (EBF) within the 0.015‒15 MeV energy range. The 2.0 mol% Tm2O3-doped glasses show a better ability to attenuate gamma-rays in comparison to other glass samples, so the addition of Tm2O3 content leads to improvement of the shielding efficiency of the prepared glasses.

  19. Cathodoluminescence and Raman characteristics of CaSO{sub 4}:Tm{sup 3+}, Cu phosphor

    Energy Technology Data Exchange (ETDEWEB)

    Ekdal, E. [Ege University, Institute of Nuclear Sciences, 35100 Bornova, İzmir (Turkey); Guinea, J. Garcia [MuseoNacional Ciencias Naturales, Jose Gutierrez Abascal 2, Madrid 28006 (Spain); Kelemen, A. [Centre for Energy Research, Radiation Safety Laboratory, P.O. Box 49, H-1121 Budapest (Hungary); Ayvacikli, M. [Celal Bayar University, Faculty of Arts and Sciences, Department of Physics, Muradiye, Manisa (Turkey); Canimoglu, A. [Nigde University, Faculty of Arts and Sciences, Department of Physics, Nigde (Turkey); Jorge, A. [MuseoNacional Ciencias Naturales, Jose Gutierrez Abascal 2, Madrid 28006 (Spain); Karali, T. [Ege University, Institute of Nuclear Sciences, 35100 Bornova, İzmir (Turkey); Can, N., E-mail: cannurdogan@yahoomail.com [Celal Bayar University, Faculty of Arts and Sciences, Department of Physics, Muradiye, Manisa (Turkey); Physics Department, Jazan University, P.O. Box 114, 45142 Jazan (Saudi Arabia)

    2015-05-15

    The physical characterization and phosphor emission spectra are presented for CaSO{sub 4} doped with Tm and Cu. All spectral wavelengths are related to electronic transitions of Tm{sup 3+} ions. The powder X-ray diffraction pattern showed that the compound exhibits orthorhombic structure and all reflections were indexed without any other secondary impurity phases. Chemical and structural properties of the samples have been characterized by means of Raman spectroscopy and environmental scanning electron microscope (ESEM) with an attached X-ray energy dispersive system (EDS). Group frequencies concept is essential point to the interpretation of the bands due to the main SO{sub 4} vibrational units and these displayed main characteristic intensive Raman bands including typical strong intensity at 1016 cm{sup −1} that corresponds to ν{sub 1}SO{sub 4} vibrational mode. From the spatially-resolved cathodoluminescence (CL) spectrum, main emission bands of Tm{sup 3+} centered at 346, 362, and 452 nm, due to the respective transitions of {sup 3}P{sub 0}→{sup 3}H{sub 4}, {sup 1}D{sub 2}→{sup 3}H{sub 6}, {sup 1}D{sub 2}→{sup 3}F{sub 4} were clearly identified. The study is novel as no such CL-ESEM data are available for this doped compound. - Highlights: • Characteristic and cathodoluminescence properties of CaSO{sub 4}:Tm{sup 3+}, Cu have been investigated. • Several sharp and strong CL emission bands due to rare earth ion were observed for rare earth doped sample. • The nature and limitation of the interaction between CaSO{sub 4} and the activator ions were discussed.

  20. Analysis of the quality of image data acquired by the LANDSAT-4 Thematic Mapper (TM) of the Black Hills area, South Dakota

    Science.gov (United States)

    Colwell, R. N. (Principal Investigator)

    1983-01-01

    The structure, format, and quality of the LANDSAT-4 TM and MSS photographic and digital products for one scene covering the Black Hills area of South Dakota were assessed and the extent to which major resource categories can be detected and identified on various photographic products generated from a subset of TM spectral bands and from all bands of the MSS was determined. The overall spectral, spatial, and radiometric quality of the TM data was found to be excellent. Agricultural fields of variable shape, size, and orientation were detected with relative ease. The addition of the short-wave infrared band (TM5) has significantly improved the ability to detect and identify crop types on single date imagery.

  1. Land-cover classification in a moist tropical region of Brazil with Landsat TM imagery.

    Science.gov (United States)

    Li, Guiying; Lu, Dengsheng; Moran, Emilio; Hetrick, Scott

    2011-01-01

    This research aims to improve land-cover classification accuracy in a moist tropical region in Brazil by examining the use of different remote sensing-derived variables and classification algorithms. Different scenarios based on Landsat Thematic Mapper (TM) spectral data and derived vegetation indices and textural images, and different classification algorithms - maximum likelihood classification (MLC), artificial neural network (ANN), classification tree analysis (CTA), and object-based classification (OBC), were explored. The results indicated that a combination of vegetation indices as extra bands into Landsat TM multispectral bands did not improve the overall classification performance, but the combination of textural images was valuable for improving vegetation classification accuracy. In particular, the combination of both vegetation indices and textural images into TM multispectral bands improved overall classification accuracy by 5.6% and kappa coefficient by 6.25%. Comparison of the different classification algorithms indicated that CTA and ANN have poor classification performance in this research, but OBC improved primary forest and pasture classification accuracies. This research indicates that use of textural images or use of OBC are especially valuable for improving the vegetation classes such as upland and liana forest classes having complex stand structures and having relatively large patch sizes.

  2. Landsat thematic mapper (TM) soil variability analysis over Webster County, Iowa

    Science.gov (United States)

    Thompson, D. R.; Henderson, K. E.; Pitts, D. E.

    1984-01-01

    Thematic mapper simulator (TMS) data acquired June 7, June 23, and July 31, 1982, and Landsat thematic mapper (TM) data acquired August 2, September 3, and October 21, 1982, over Webster County, Iowa, were examined for within-field soil effects on corn and soybean spectral signatures. It was found that patterns displayed on various computer-generated map products were in close agreement with the detailed soil survey of the area. The difference in spectral values appears to be due to a combination of subtle soil properties and crop growth patterns resulting from the different soil properties. Bands 4 (0.76-.90 micron), 5 (1.55-1.75 micron), and 7 (2.08-2.35 micron) were found to be responding to the within-field soil variability even with increasing ground cover. While these results are preliminary, they do indicate that the soil influence on the vegetation is being detected by TM and should provide improved information relating to crop and soil properties.

  3. Stability of (Fe-Tm-B) amorphous alloys: relaxation and crystallization phenomena

    International Nuclear Information System (INIS)

    Zemcik, T.

    1994-01-01

    Fe-Tm-B base (TM = transition metal) amorphous alloys (metallic glasses) are thermodynamically metastable. This limits their use as otherwise favourable materials, e.g. magnetically soft, corrosion resistant and mechanically firm. By analogy of the mechanical strain-stress dependence, at a certain degree of thermal activation the amorphous structure reaches its limiting state where it changes its character and physical properties. Relaxation and early crystallization processes in amorphous alloys, starting already around 100 C, are reviewed involving subsequently stress relief, free volume shrinking, topological and chemical ordering, pre-crystallization phenomena up to partial (primary) crystallization. Two diametrically different examples are demonstrated from among the soft magnetic materials: relaxation and early crystallization processes in the Fe-Co-B metallic glasses and controlled crystallization of amorphous ribbons yielding rather modern nanocrystalline ''Finemet'' alloys where late relaxation and pre-crystallization phenomena overlap when forming extremely dispersive and fine-grained nanocrystals-in-amorphous-sauce structure. Moessbauer spectroscopy seems to be unique for magnetic and phase analysis of such complicated systems. (orig.)

  4. Inactivation of Tm6sf2, a Gene Defective in Fatty Liver Disease, Impairs Lipidation but Not Secretion of Very Low Density Lipoproteins.

    Science.gov (United States)

    Smagris, Eriks; Gilyard, Shenise; BasuRay, Soumik; Cohen, Jonathan C; Hobbs, Helen H

    2016-05-13

    A missense mutation (E167K) in TM6SF2 (transmembrane 6 superfamily member 2), a polytopic protein of unknown function, is associated with the full spectrum of fatty liver disease. To investigate the role of TM6SF2 in hepatic triglyceride (TG) metabolism, we inactivated the gene in mice. Chronic inactivation of Tm6sf2 in mice is associated with hepatic steatosis, hypocholesterolemia, and transaminitis, thus recapitulating the phenotype observed in humans. No dietary challenge was required to elicit the phenotype. Immunocytochemical and cell fractionation studies revealed that TM6SF2 was present in the endoplasmic reticulum and Golgi complex, whereas the excess neutral lipids in the Tm6sf2(-/-) mice were located in lipid droplets. Plasma VLDL-TG levels were reduced in the KO animals due to a 3-fold decrease in VLDL-TG secretion rate without any associated reduction in hepatic apoB secretion. Both VLDL particle size and plasma cholesterol levels were significantly reduced in KO mice. Despite levels of TM6SF2 protein being 10-fold higher in the small intestine than in the liver, dietary lipid absorption was only modestly reduced in the KO mice. Our data, taken together, reveal that TM6SF2 is required to mobilize neutral lipids for VLDL assembly but is not required for secretion of apoB-containing lipoproteins. Despite TM6SF2 being located in the endoplasmic reticulum and Golgi complex, the lipids that accumulate in its absence reside in lipid droplets. © 2016 by The American Society for Biochemistry and Molecular Biology, Inc.

  5. 41 CFR 101-42.1102-2 - Polychlorinated biphenyls.

    Science.gov (United States)

    2010-07-01

    ... things, as insulators and coolants for electric cables and components such as transformers and capacitors... Protection Agency regulation (40 CFR 761), applicable State laws, and 41 CFR 101-42.1102-2. For proper... the warning and certification typed or stamped on the face of each copy of the distribution document...

  6. Self-imaging effect of TM modes in photonic crystal multimode waveguides only exhibiting band gaps for TE modes

    International Nuclear Information System (INIS)

    Yu Tianbao; Jiang Xiaoqing; Yang Jianyi; Zhou Haifeng; Liao Qinghua; Wang Minghua

    2007-01-01

    This Letter presents the properties of transverse-magnetic (TM) modes in multimode photonic crystal waveguides (PCWs), which only exhibit photonic band gaps for transverse-electric (TE) modes. A good equivalent model is applied to analysis the designed structures on the basis of multimode interference effect and self-imaging principle. The performance shows that the TM modes can also be propagated with high efficiency, and resemble index-guided modes owing to the combination of total internal reflection (TIR) and distribution Bragg reflection. It provides a novel way to realize the components for both TM and TE polarizations by combining PBG and TIR effect in PCWs. As one of potential applications, polarization-insensitive power splitter based on the proposed structures can be designed

  7. The retrovirus MA and PreTM proteins follow immature MVL cores

    DEFF Research Database (Denmark)

    Andersen, Klaus Bahl

    2013-01-01

    Detergent can dissolve retrovirus, exept the immature core. Here we show that the Matrix protein (MA) and the Transmembrane protein in its immature form (PreTM) bind to the retrovirus core. These attachments explain the attachment in the virus particle and the dynamics of the ability to fuse with...

  8. Monte Carlo and Ab-initio calculation of TM (Ti, V, Cr, Mn, Fe, Co, Ni) doped MgH{sub 2} hydride: GGA and SIC approximation

    Energy Technology Data Exchange (ETDEWEB)

    Salmani, E., E-mail: elmehdisalmani@gmail.com [LMPHE (URAC12), Faculty of Sciences, Mohammed V University in Rabat (Morocco); Laghrissi, A.; Lamouri, R. [LMPHE (URAC12), Faculty of Sciences, Mohammed V University in Rabat (Morocco); Benchafia, E. [Department of Materials Science and Engineering, New Jersey Institute of Technology, Newark, NJ 07102 (United States); Ez-Zahraouy, H. [LMPHE (URAC12), Faculty of Sciences, Mohammed V University in Rabat (Morocco); Benyoussef, A. [Institute for Nanomaterials and Nanotechnologies, MAScIR, Rabat (Morocco)

    2017-02-15

    MgH{sub 2}: TM (TM: V, Cr, Mn, Fe, Co, Ni) based dilute magnetic semiconductors (DMS) are investigated using first principle calculations. Our results show that the ferromagnetic state is stable when TM introduces magnetic moments as well as intrinsic carriers in TM: Co, V, Cr, Ti; Mg{sub 0.95}TM{sub 0.05}H{sub 2}. Some of the DMS Ferro magnets under study exhibit a half-metallic behavior, which make them suitable for spintronic applications. The double exchange is shown to be the underlying mechanism responsible for the magnetism of such materials. The exchange interactions obtained from first principle calculations and used in a classical Ising model by a Monte Carlo approach resulted in ferromagnetic states with Curie temperatures within the ambient conditions. - Highlights: • The half-metallic aspect was proven to take place for Ti, Cr, Co and Ni. • The TM impurities are shown to introduce the magnetic moment that makes MgH{sub 2} good candidates for spintronic applications.

  9. 78 FR 63434 - International Mailing Services: Proposed Price Changes-Exigent

    Science.gov (United States)

    2013-10-24

    ...%) Registered Mail TM (4.2%) Return Receipt (4.2%) International Business Reply TM Cards and Envelopes (2.8... Duplicate copy of PS Form 3606 1.30 * * * * * International Business Reply Service (382) [For each country that offers International Business Reply service, revise the fees to read as follows:] Fee: Envelopes...

  10. The Eighty Six Hα Spectra from the Orion Nebula (M42, Sh2-281)

    Indian Academy of Sciences (India)

    40′×40′) of the Orion Nebula (NGC1976, M42, Sh2-281) have been obtained using DEFPOS spectrometer with a circular field of view of 4′ at TUBITAK National Observatory (TUG, Antalya, Turkey). Measurements provide information ...

  11. Evaluation of Different Topographic Corrections for Landsat TM Data by Prediction of Foliage Projective Cover (FPC in Topographically Complex Landscapes

    Directory of Open Access Journals (Sweden)

    Sisira Ediriweera

    2013-12-01

    Full Text Available The reflected radiance in topographically complex areas is severely affected by variations in topography; thus, topographic correction is considered a necessary pre-processing step when retrieving biophysical variables from these images. We assessed the performance of five topographic corrections: (i C correction (C, (ii Minnaert, (iii Sun Canopy Sensor (SCS, (iv SCS + C and (v the Processing Scheme for Standardised Surface Reflectance (PSSSR on the Landsat-5 Thematic Mapper (TM reflectance in the context of prediction of Foliage Projective Cover (FPC in hilly landscapes in north-eastern Australia. The performance of topographic corrections on the TM reflectance was assessed by (i visual comparison and (ii statistically comparing TM predicted FPC with ground measured FPC and LiDAR (Light Detection and Ranging-derived FPC estimates. In the majority of cases, the PSSSR method performed best in terms of eliminating topographic effects, providing the best relationship and lowest residual error when comparing ground measured FPC and LiDAR FPC with TM predicted FPC. The Minnaert, C and SCS + C showed the poorest performance. Finally, the use of TM surface reflectance, which includes atmospheric correction and broad Bidirectional Reflectance Distribution Function (BRDF effects, seemed to account for most topographic variation when predicting biophysical variables, such as FPC.

  12. Correlations between transmembrane 4 L6 family member 5 (TM4SF5, CD151, and CD63 in liver fibrotic phenotypes and hepatic migration and invasive capacities.

    Directory of Open Access Journals (Sweden)

    Minkyung Kang

    Full Text Available Transmembrane 4 L6 family member 5 (TM4SF5 is overexpressed during CCl4-mediated murine liver fibrosis and in human hepatocellular carcinomas. The tetraspanins form tetraspanin-enriched microdomains (TEMs consisting of large membrane protein complexes on the cell surface. Thus, TM4SF5 may be involved in the signal coordination that controls liver malignancy. We investigated the relationship between TM4SF5-positive TEMs with liver fibrosis and tumorigenesis, using normal Chang hepatocytes that lack TM4SF5 expression and chronically TGFβ1-treated Chang cells that express TM4SF5. TM4SF5 expression is positively correlated with tumorigenic CD151 expression, but is negatively correlated with tumor-suppressive CD63 expression in mouse fibrotic and human hepatic carcinoma tissues, indicating cooperative roles of the tetraspanins in liver malignancies. Although CD151 did not control the expression of TM4SF5, TM4SF5 appeared to control the expression levels of CD151 and CD63. TM4SF5 interacted with CD151, and caused the internalization of CD63 from the cell surface into late lysosomal membranes, presumably leading to terminating the tumor-suppressive functions of CD63. TM4SF5 could overcome the tumorigenic effects of CD151, especially cell migration and extracellular matrix (ECM-degradation. Taken together, TM4SF5 appears to play a role in liver malignancy by controlling the levels of tetraspanins on the cell surface, and could provide a promising therapeutic target for the treatment of liver malignancies.

  13. Fabrication and evaluation of chitosan/NaYF4:Yb3+/Tm3+ upconversion nanoparticles composite beads based on the gelling of Pickering emulsion droplets

    International Nuclear Information System (INIS)

    Yan, Huiqiong; Chen, Xiuqiong; Shi, Jia; Shi, Zaifeng; Sun, Wei; Lin, Qiang; Wang, Xianghui; Dai, Zihao

    2017-01-01

    The rare earth ion doped upconversion nanoparticles (UCNPs) synthesized by hydrophobic organic ligands possess poor solubility and low fluorescence quantum yield in aqueous media. To conquer this issue, NaYF 4 :Yb 3+ /Tm 3+ UCNPs, synthesized by a hydrothermal method, were coated with F127 and then assembled with chitosan to fabricate the chitosan/NaYF 4 :Yb 3+ /Tm 3+ composite beads (CS/NaYF 4 :Yb 3+ /Tm 3+ CBs) by Pickering emulsion system. The characterization results revealed that the as-synthesized NaYF 4 :Yb 3+ /Tm 3+ UCNPs with an average size of 20 nm exhibited spherical morphology, high crystallinity and characteristic emission upconversion fluorescence with an overall blue color output. The NaYF 4 :Yb 3+ /Tm 3+ UCNPs were successfully conjugated on the surface of chitosan beads by the gelling of emulsion droplets. The resultant CS/NaYF 4 :Yb 3+ /Tm 3+ CBs showed good upconversion luminescent property, drug-loading capacity, release performance and excellent biocompatibility, exhibiting great potentials in targeted drug delivery and tissue engineering with potential tracking capability and lasting release performance. - Highlights: • NaYF 4 :Yb 3+ /Tm 3+ UCNPs were coated by F127 to improve aqueous dispersibility. • NaYF 4 :Yb 3+ /Tm 3+ UCNPs were assembled with chitosan to fabricate the composite beads (CMs). • Pickering emulsions stabilized by UCNPs exhibited uniform and satisfactory emulsion droplets. • The CMs prepared by the gelling of emulsion droplet preserved upconversion luminescent property. • The resultant CMs showed good drug-loading capacity, release performance and biocompatibility.

  14. Changes in trait brainwave power and coherence, state and trait anxiety after three-month transcendental meditation (TM) practice.

    Science.gov (United States)

    Tomljenović, Helena; Begić, Dražen; Maštrović, Zora

    2016-03-01

    The amount of studies showing different benefits of practicing meditation is growing. EEG brainwave patterns objectively reflect both the cognitive processes and objects of meditation. This study aimed to examine the effects of transcendental meditation (TM) practice on baseline EEG brainwave patterns (outside of meditation) and to examine weather TM reduces state and trait anxiety. Standard EEG recordings were conducted on volunteer participants (N=12), all students or younger employed people, before and after a three-month meditation training. Artifact-free 100-second epochs were selected and analyzed by Fast Fourier Transformation (FFT) analysis. Endlers Multidimensional Anxiety Scales (EMAS) were used to assess anxiety levels. Power (μV(2)) and coherence levels were compared in the alpha, beta, theta and delta frequency band. Changes in EEG patterns after meditation practice were found mostly in the theta band. An interaction effect was found on the left hemisphere (pmeditation practice. Most of the changes were found in the occipital and temporal areas, less in the central and frontal areas. State anxiety decreased after TM practice. Findings suggest TM practice could be helpful in treating different kinds of disorders, especially anxiety disorders.

  15. The Sloan Lens ACS Survey. XIII. Discovery of 40 New Galaxy-scale Strong Lenses

    Science.gov (United States)

    Shu, Yiping; Brownstein, Joel R.; Bolton, Adam S.; Koopmans, Léon V. E.; Treu, Tommaso; Montero-Dorta, Antonio D.; Auger, Matthew W.; Czoske, Oliver; Gavazzi, Raphaël; Marshall, Philip J.; Moustakas, Leonidas A.

    2017-12-01

    We present the full sample of 118 galaxy-scale strong-lens candidates in the Sloan Lens ACS (SLACS) Survey for the Masses (S4TM) Survey, which are spectroscopically selected from the final data release of the Sloan Digital Sky Survey. Follow-up Hubble Space Telescope (HST) imaging observations confirm that 40 candidates are definite strong lenses with multiple lensed images. The foreground-lens galaxies are found to be early-type galaxies (ETGs) at redshifts 0.06–0.44, and background sources are emission-line galaxies at redshifts 0.22–1.29. As an extension of the SLACS Survey, the S4TM Survey is the first attempt to preferentially search for strong-lens systems with relatively lower lens masses than those in the pre-existing strong-lens samples. By fitting HST data with a singular isothermal ellipsoid model, we find that the total projected mass within the Einstein radius of the S4TM strong-lens sample ranges from 3 × 1010 M ⊙ to 2 × 1011 M ⊙. In Shu et al., we have derived the total stellar mass of the S4TM lenses to be 5 × 1010 M ⊙ to 1 × 1012 M ⊙. Both the total enclosed mass and stellar mass of the S4TM lenses are on average almost a factor of 2 smaller than those of the SLACS lenses, which also represent the typical mass scales of the current strong-lens samples. The extended mass coverage provided by the S4TM sample can enable a direct test, with the aid of strong lensing, for transitions in scaling relations, kinematic properties, mass structure, and dark-matter content trends of ETGs at intermediate-mass scales as noted in previous studies. Based on observations made with the NASA/ESA Hubble Space Telescope (HST), obtained at the Space Telescope Science Institute, which is operated by AURA, Inc., under NASA contract NAS 5-26555. These observations are associated with HST program #12210.

  16. Tunable multicolor and white-light upconversion luminescence in Yb3+/Tm3+/Ho3+ tri-doped NaYF4 micro-crystals.

    Science.gov (United States)

    Lin, Hao; Xu, Dekang; Teng, Dongdong; Yang, Shenghong; Zhang, Yueli

    2015-09-01

    NaYF4 micro-crystals with various concentrations of Yb(3+) /Tm(3+) /Ho(3+) were prepared successfully via a simple and reproducible hydrothermal route using EDTA as the chelating agent. Their phase structure and surface morphology were studied using powder X-ray diffraction (XRD) and scanning electron microscopy (SEM). The XRD patterns revealed that all the samples were pure hexagonal phase NaYF4. SEM images showed that Yb(3+)/Tm(3+)/Ho(3+) tri-doped NaYF4 were hexagonal micro-prisms. Upconversion photoluminescence spectra of Yb(3+)/Tm(3+)/Ho(3+) tri-doped NaYF4 micro-crystals with various dopant concentrations under 980 nm excitation with a 665 mW pump power were studied. Tunable multicolor (purple, purplish blue, yellowish green, green) and white light were achieved by simply adjusting the Ho(3+) concentration in 20%Yb(3+)/1%Tm(3+)/xHo(3+) tri-doped NaYF4 micro-crystals. Furthermore, white-light emissions could be obtained using different pump powers in 20%Yb(3+)/1%Tm(3+)/1%Ho(3+) tri-doped NaYF4 micro-crystals at 980 nm excitation. The pump power-dependent intensity relationship was studied and relevant energy transfer processes were discussed in detail. The results suggest that Yb(3+)/Tm(3+) Ho(3+) tri-doped NaYF4 micro-crystals have potential applications in optoelectronic devices such as photovoltaic, plasma display panel and white-light-emitting diodes. Copyright © 2014 John Wiley & Sons, Ltd.

  17. Induction of host defences by Rhizobium during ineffective nodulation of pea (Pisum sativum L.) carrying symbiotically defective mutations sym40 (PsEFD), sym33 (PsIPD3/PsCYCLOPS) and sym42.

    Science.gov (United States)

    Ivanova, Kira A; Tsyganova, Anna V; Brewin, Nicholas J; Tikhonovich, Igor A; Tsyganov, Viktor E

    2015-11-01

    Rhizobia are able to establish a beneficial interaction with legumes by forming a new organ, called the symbiotic root nodule, which is a unique ecological niche for rhizobial nitrogen fixation. Rhizobial infection has many similarities with pathogenic infection and induction of defence responses accompanies both interactions, but defence responses are induced to a lesser extent during rhizobial infection. However, strong defence responses may result from incompatible interactions between legumes and rhizobia due to a mutation in either macro- or microsymbiont. The aim of this research was to analyse different plant defence reactions in response to Rhizobium infection for several pea (Pisum sativum) mutants that result in ineffective symbiosis. Pea mutants were examined by histochemical and immunocytochemical analyses, light, fluorescence and transmission electron microscopy and quantitative real-time PCR gene expression analysis. It was observed that mutations in pea symbiotic genes sym33 (PsIPD3/PsCYCLOPS encoding a transcriptional factor) and sym40 (PsEFD encoding a putative negative regulator of the cytokinin response) led to suberin depositions in ineffective nodules, and in the sym42 there were callose depositions in infection thread (IT) and host cell walls. The increase in deposition of unesterified pectin in IT walls was observed for mutants in the sym33 and sym42; for mutant in the sym42, unesterified pectin was also found around degrading bacteroids. In mutants in the genes sym33 and sym40, an increase in the expression level of a gene encoding peroxidase was observed. In the genes sym40 and sym42, an increase in the expression levels of genes encoding a marker of hypersensitive reaction and PR10 protein was demonstrated. Thus, a range of plant defence responses like suberisation, callose and unesterified pectin deposition as well as activation of defence genes can be triggered by different pea single mutations that cause perception of an otherwise

  18. Activation of the CXCR3 chemokine receptor through anchoring of a small molecule chelator ligand between TM-III, -IV, and -VI

    DEFF Research Database (Denmark)

    Rosenkilde, Mette M; Andersen, Michael B; Nygaard, Rie

    2006-01-01

    modeling and molecular simulations combined with mutational analysis indicated that the metal ion site-anchored chelators act as agonists by establishing an aromatic-aromatic, second-site interaction with TyrVI:16 on the inner face of TM-VI. It is noteworthy that this interaction required......Seven transmembrane segment (7TM) receptors are activated through a common, still rather unclear molecular mechanism by a variety of chemical messengers ranging from monoamines to large proteins. By introducing a His residue at position III:05 in the CXCR3 receptor a metal ion site was built...... between the extracellular ends of transmembrane (TM) III and TM-IV to anchor aromatic chelators at a location corresponding to the presumed binding pocket for adrenergic receptor agonists. In this construct, free metal ions had no agonistic effect in accordance with the optimal geometry of the metal ion...

  19. The spectroscopy investigation of ZnWO{sub 4}:Tm{sup 3+} single crystal

    Energy Technology Data Exchange (ETDEWEB)

    Yang Fugui, E-mail: ruopiao@fjirsm.ac.cn [Department of Electronic Information Science, Fujian Jiangxia University, Fuzhou, Fujian 350108 (China); Tu Chaoyang [Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, Fujian 350002 (China)

    2012-09-15

    Highlights: Black-Right-Pointing-Pointer The spectroscopy and refractive index of single crystal ZnWO{sub 4}:Tm{sup 3+} are investigated systematically. Black-Right-Pointing-Pointer The Judd-Ofelt parameters are obtained. Black-Right-Pointing-Pointer The gain cross sections at {approx}2 {mu}m are estimated by reciprocity method (RM). Black-Right-Pointing-Pointer The laser operation at {approx}2 {mu}m is discussed. - Abstract: The single crystal ZnWO{sub 4}:Tm{sup 3+} has been grown by Czochralski method. The XRD, refractive index, absorption and fluorescence spectra are measured. The Judd-Ofelt parameters{Omega}{sub 2}, {Omega}{sub 4}, {Omega}{sub 6} are obtained to be 6.3 Multiplication-Sign 10{sup -20}, 1.3 Multiplication-Sign 10{sup -20}, 1.4 Multiplication-Sign 10{sup -20} cm{sup 2}, respectively. The fluorescence decay time of the {sup 3}H{sub 4} level is measured to be 0.113 ms and the quantum efficiency is 57%. The gain cross sections corresponding to {sup 3}F{sub 4}{yields}{sup 3}H{sub 6} transition at {approx}2 {mu}m are estimated by the reciprocity method (RM). The strong gain at {approx}2 {mu}m indicates that the ZnWO{sub 4}:Tm{sup 3+} crystal is a promising laser host for {approx}2 {mu}m laser.

  20. 1.8 μm luminescent properties and energy transfer of Yb{sup 3+}/Tm{sup 3+} co-doped α-NaYF{sub 4} single crystals

    Energy Technology Data Exchange (ETDEWEB)

    Feng, Zhigang [Key Laboratory of Photo-electronic Materials, Ningbo University, Ningbo, Zhejiang, 315211 (China); Xia, Haiping, E-mail: hpxcm@nbu.edu.cn [Key Laboratory of Photo-electronic Materials, Ningbo University, Ningbo, Zhejiang, 315211 (China); Wang, Cheng; Zhang, Zhixiong; Jiang, Dongsheng; Zhang, Jian; He, Shinan; Tang, Qingyang; Sheng, Qiguo; Gu, Xuemei; Zhang, Yuepin [Key Laboratory of Photo-electronic Materials, Ningbo University, Ningbo, Zhejiang, 315211 (China); Chen, Baojiu [Department of Physics, Dalian Maritime University, Dalian, Liaoning Province, 116026 (China); Jiang, Haochuan, E-mail: jianghaochuan@nimte.ac.cn [Ningbo Institute of Materials Technology and Engineering, The Chinese Academy of Sciences, Ningbo, Zhejiang, 315211 (China)

    2016-09-25

    This paper reports on successful preparation of α-NaYF{sub 4} single crystals co-doped with ∼1.9 mol% Tm{sup 3+} and various concentrations (3.85 mol%, 7.69 mol%, 11.54 mol%, 15.38 mol%) of Yb{sup 3+} by using a flux-Bridgman method. The fluorescence decay curve was measured to investigate the luminescent properties of the Yb{sup 3+}/Tm{sup 3+} co-doped α-NaYF{sub 4}, and the energy transfer process from Yb{sup 3+} to Tm{sup 3+}; the J-O intensity parameters of Tm{sup 3+} were further calculated and analyzed according to the absorption spectra. Results show that, an intense 1.8 μm emission was achieved with Yb{sup 3+} as sensitizer for Tm{sup 3+} in the α-NaYF{sub 4} single crystal under the excitation of 980 nm LD (Laser Diode) because of the strong energy transfer from Yb{sup 3+} to Tm{sup 3+}. The maximum emission intensity at 1.8 μm is obtained at about 15.38 mol% doping concentration of Yb{sup 3+} when the concentration of Tm{sup 3+} ions is fixed at ∼1.90 mol% in the current research. Moreover, the calculated maximum value of emission cross section at 1.8 μm is 1.63 × 10{sup −20} cm{sup 2} for 3.85 mol% Yb{sup 3+}/1.9 mol% Tm{sup 3+} sample, and the obtained energy transfer rate (W{sub ET}) and energy transfer efficiency (η) are 1543 s{sup −1} and 83.8%, respectively. Our analysis of the fluorescence dynamics indicates that electric dipole-dipole interaction is dominant for the energy transfer from Yb{sup 3+} ions to Tm{sup 3+} ions by using Inokuti-Hirayama’s model. - Highlights: • The Tm{sup 3+}/Yb{sup 3+} co-doped α-NaYF{sub 4} single crystals were grown by Bridgman method. • The 1.8 μm emission intensity is obtained at 15.38 mol% Yb{sup 3+}/1.90 mol% Tm{sup 3+} sample. • The maximum value of emission cross section at 1.8 μm is 1.63 × 10{sup −20} cm{sup 2}. • The energy transfer rate is 1543 s{sup −1} and energy transfer efficiency is 83.8%. • The physical mechanism for energy transfer from Yb{sup 3+} to Tm{sup 3+} ions