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Sample records for timing discriminator circuit

  1. A CMOS integrated timing discriminator circuit for fast scintillation counters

    International Nuclear Information System (INIS)

    Jochmann, M.W.

    1998-01-01

    Based on a zero-crossing discriminator using a CR differentiation network for pulse shaping, a new CMOS integrated timing discriminator circuit is proposed for fast (t r ≥ 2 ns) scintillation counters at the cooler synchrotron COSY-Juelich. By eliminating the input signal's amplitude information by means of an analog continuous-time divider, a normalized pulse shape at the zero-crossing point is gained over a wide dynamic input amplitude range. In combination with an arming comparator and a monostable multivibrator this yields in a highly precise timing discriminator circuit, that is expected to be useful in different time measurement applications. First measurement results of a CMOS integrated logarithmic amplifier, which is part of the analog continuous-time divider, agree well with the corresponding simulations. Moreover, SPICE simulations of the integrated discriminator circuit promise a time walk well below 200 ps (FWHM) over a 40 dB input amplitude dynamic range

  2. Photonic integrated circuit as a picosecond pulse timing discriminator.

    Science.gov (United States)

    Lowery, Arthur James; Zhuang, Leimeng

    2016-04-18

    We report the first experimental demonstration of a compact on-chip optical pulse timing discriminator that is able to provide an output voltage proportional to the relative timing of two 60-ps input pulses on separate paths. The output voltage is intrinsically low-pass-filtered, so the discriminator forms an interface between high-speed optics and low-speed electronics. Potential applications include timing synchronization of multiple pulse trains as a precursor for optical time-division multiplexing, and compact rangefinders with millimeter dimensions.

  3. Development of a pulse shape discrimination circuit

    International Nuclear Information System (INIS)

    Ye Bangjiao; Fan Wei; Fan Yangmei; Yu Xiaoqi; Mei Wen; Wang Zhongmin; Han Rongdian; Xiao Zhenxi

    1994-01-01

    A pulse shape discrimination circuit was designed and used in an experiment measuring double-differential cross sections of (n, charged particle) reaction; to identify p, α and γ. The performance of the circuit was tested. With this circuit, excellent identification of p, α and γ was obtained. ((orig.))

  4. Fast timing discriminator

    International Nuclear Information System (INIS)

    Lo, C.C.

    1977-01-01

    The processing of pulses with very fast risetimes for timing purposes involves many problems because of the large equivalent bandwidths involved. For pulses with risetimes in the 150 ps range (and full widths at half maximum (FWHM) of 400 ps) bandwidths in excess of 1GHz are required. Furthermore, these very narrow pulses with current amplitudes as small as 1 mA carry very small charges ( -12 coulomb), therefore, requiring very sensitive trigger circuits. The difficulty increases when timing characteristics in the picosecond range are sought especially when a wide input signal amplitude range causes a time-walk problem. The fast timing discriminator described has a time-walk of approximately +-75 ps over the input signal range from 80 mV to 3V. A schematic of the discriminator is included, and operation and performance are discussed

  5. Multipurpose discriminator with accurate time coupling

    International Nuclear Information System (INIS)

    Baldin, B.Yu.; Krumshtejn, Z.V.; Ronzhin, A.I.

    1977-01-01

    The principle diagram of a multipurpose discriminator is described, designed on the basis of a wide-band differential amplifier. The discriminator has three independent channels: the timing channel, the lower level discriminator and the control channel. The timing channel and the lower level discriminator are connected to a coincidence circuit. Three methods of timing are used: a single threshold, a double threshold with timing on the pulse front, and a constant fraction timing. The lower level discriminator is a wide-band amplifier with an adjustable threshold. The investigation of compensation characteristics of the discriminator has shown that the time shift of the discriminator output in the constant fraction timing regime does not exceed +-75 ns for the input signal range of 1:85. The time resolution was found to be 20 ns in the 20% energy range near the photo-peak maximum of 60 Co γ source

  6. Tunnel Diode Discriminator with Fixed Dead Time

    DEFF Research Database (Denmark)

    Diamond, J. M.

    1965-01-01

    A solid state discriminator for the range 0.4 to 10 V is described. Tunnel diodes are used for the discriminator element and in a special fixed dead time circuit. An analysis of temperature stability is presented. The regulated power supplies are described, including a special negative resistance...

  7. Explicit logic circuits discriminate neural states.

    Directory of Open Access Journals (Sweden)

    Lane Yoder

    Full Text Available The magnitude and apparent complexity of the brain's connectivity have left explicit networks largely unexplored. As a result, the relationship between the organization of synaptic connections and how the brain processes information is poorly understood. A recently proposed retinal network that produces neural correlates of color vision is refined and extended here to a family of general logic circuits. For any combination of high and low activity in any set of neurons, one of the logic circuits can receive input from the neurons and activate a single output neuron whenever the input neurons have the given activity state. The strength of the output neuron's response is a measure of the difference between the smallest of the high inputs and the largest of the low inputs. The networks generate correlates of known psychophysical phenomena. These results follow directly from the most cost-effective architectures for specific logic circuits and the minimal cellular capabilities of excitation and inhibition. The networks function dynamically, making their operation consistent with the speed of most brain functions. The networks show that well-known psychophysical phenomena do not require extraordinarily complex brain structures, and that a single network architecture can produce apparently disparate phenomena in different sensory systems.

  8. TIME CALIBRATED OSCILLOSCOPE SWEEP CIRCUIT

    Science.gov (United States)

    Smith, V.L.; Carstensen, H.K.

    1959-11-24

    An improved time calibrated sweep circuit is presented, which extends the range of usefulness of conventional oscilloscopes as utilized for time calibrated display applications in accordance with U. S. Patent No. 2,832,002. Principal novelty resides in the provision of a pair of separate signal paths, each of which is phase and amplitude adjustable, to connect a high-frequency calibration oscillator to the output of a sawtooth generator also connected to the respective horizontal deflection plates of an oscilloscope cathode ray tube. The amplitude and phase of the calibration oscillator signals in the two signal paths are adjusted to balance out feedthrough currents capacitively coupled at high frequencies of the calibration oscillator from each horizontal deflection plate to the vertical plates of the cathode ray tube.

  9. Semi-custom integrated circuit amplifier and level discriminator for nuclear and space instruments

    International Nuclear Information System (INIS)

    Hahn, S.F.; Cafferty, M.M.

    1991-01-01

    This paper reports on the development an extra fast current feedback amplifier and a level discriminator employing a dielectrically-isolated bipolar, semi-custom Application Specific Integrated Circuit (ASIC) process. These devices are specifically designed for instruments aboard spacecrafts or in portable packages requiring low power and weight. The amplifier adopts current feedback for a unity-gain bandwidth of 90 MHz while consuming 50 mW. The level discriminator uses a complementary output driver for balanced positive and negative response times. The power consumption of these devices can be programmed by external resistors for optimal speed and power trade-off

  10. Semi-custom integrated circuit amplifier and level discriminator for nuclear and space instruments

    International Nuclear Information System (INIS)

    Hahn, S.F.; Cafferty, M.M.

    1990-01-01

    This paper reports an extra fast current feedback amplifier and a level discriminator developed employing a dielectrically isolated bipolar, semi-custom Application Specific Integrated Circuit (ASIC) process. These devices are specifically designed for instruments aboard spacecrafts or in portable packages requiring low power and weight. The amplifier adopts current feedback for a unity- gain bandwidth of 90 MHz while consuming 50 mW. The level discriminator uses a complementary output driver for balanced positive and negative response times. The power consumption of these devices can be programmed by external resistors for optimal speed and power trade-off

  11. Time domain analog circuit simulation

    NARCIS (Netherlands)

    Fijnvandraat, J.G.; Houben, S.H.M.J.; Maten, ter E.J.W.; Peters, J.M.F.

    2006-01-01

    Recent developments of new methods for simulating electric circuits are described. Emphasis is put on methods that fit existing datastructures for backward differentiation formulae methods. These methods can be modified to apply to hierarchically organized datastructures, which allows for efficient

  12. Interconnect rise time in superconducting integrating circuits

    International Nuclear Information System (INIS)

    Preis, D.; Shlager, K.

    1988-01-01

    The influence of resistive losses on the voltage rise time of an integrated-circuit interconnection is reported. A distribution-circuit model is used to present the interconnect. Numerous parametric curves are presented based on numerical evaluation of the exact analytical expression for the model's transient response. For the superconducting case in which the series resistance of the interconnect approaches zero, the step-response rise time is longer but signal strength increases significantly

  13. A precision timing discriminator for high density detector systems

    International Nuclear Information System (INIS)

    Turko, B.T.; Smith, R.C.

    1992-01-01

    Most high resolution time measurement techniques require discriminators that accurately make the time arrival of events regardless of their intensity. Constant fraction discriminators or zero-crossing discriminators are generally used. In this paper, the authors describe a zero-crossing discriminator that accurately determines the peak of a quasi-Gaussian waveform by differentiating it and detecting the resulting zero-crossing. Basically, it consists of a fast voltage comparator and tow integrating networks: an RC section and an LR section used in a way that keeps the input impedance purely resistive. A time walk of 100 ps in an amplitude range exceeding 100:1 has been achieved for wave-forms from 1.5 ns to 15 ns FWHM. An arming level discriminator is added to eliminate triggering by noise. Easily implemented in either monolithic or hybrid technology, the circuit is suitable for large multichannel detector systems where size and power dissipation are crucial. Circuit diagrams and typical measured data are also presented

  14. Double threshold discriminator for timing measurements

    International Nuclear Information System (INIS)

    Frolov, A.R.; Oslopova, T.V.; Pestov, Yu.N.

    1995-01-01

    The new type of a discriminator is based on the idea of simultaneous time measurements at two different thresholds for each pulse. Instead of using two independent electronic TDC channels this discriminator produces an output pulse with the timing taking into account the information from two time measurements ''on-line''. The operation principle, analytical calculations and experimental results are presented. The time walk of the discriminator at the level of 10 ps in the range of the input pulse height of 0.2-1.5 V has been obtained. ((orig.))

  15. Study of signal discrimination for timing measurements

    CERN Document Server

    Krepelkova, Marta

    2017-01-01

    The timing detectors of the CMS-TOTEM Precision Proton Spectrometer (CT-PPS) are currently read out using discrete components, separated into three boards; the first board hosts the sensors and the amplifiers, the second one hosts the discriminators and the third is dedicated to the Time to Digital Converter (TDC) and to the interface with the data acquisition system (DAQ). This work proposes a new front-end electronics for the timing detector, with sensors, amplifiers and discriminators integrated on the same board. We simulated an updated version of the amplifier together with a discriminator designed using commercial components. We decided to use an LVDS buffer as a discriminator, because of its cost, availability, speed and lo w power consumption. As a proof of concept, we used the LVDS input of an FPGA to discriminate signals produced by a detector prototype, using a radioactive source.

  16. Spike timing precision of neuronal circuits.

    Science.gov (United States)

    Kilinc, Deniz; Demir, Alper

    2018-04-17

    Spike timing is believed to be a key factor in sensory information encoding and computations performed by the neurons and neuronal circuits. However, the considerable noise and variability, arising from the inherently stochastic mechanisms that exist in the neurons and the synapses, degrade spike timing precision. Computational modeling can help decipher the mechanisms utilized by the neuronal circuits in order to regulate timing precision. In this paper, we utilize semi-analytical techniques, which were adapted from previously developed methods for electronic circuits, for the stochastic characterization of neuronal circuits. These techniques, which are orders of magnitude faster than traditional Monte Carlo type simulations, can be used to directly compute the spike timing jitter variance, power spectral densities, correlation functions, and other stochastic characterizations of neuronal circuit operation. We consider three distinct neuronal circuit motifs: Feedback inhibition, synaptic integration, and synaptic coupling. First, we show that both the spike timing precision and the energy efficiency of a spiking neuron are improved with feedback inhibition. We unveil the underlying mechanism through which this is achieved. Then, we demonstrate that a neuron can improve on the timing precision of its synaptic inputs, coming from multiple sources, via synaptic integration: The phase of the output spikes of the integrator neuron has the same variance as that of the sample average of the phases of its inputs. Finally, we reveal that weak synaptic coupling among neurons, in a fully connected network, enables them to behave like a single neuron with a larger membrane area, resulting in an improvement in the timing precision through cooperation.

  17. Count-doubling time safety circuit

    International Nuclear Information System (INIS)

    Keefe, D.J.; McDowell, W.P.; Rusch, G.K.

    1981-01-01

    There is provided a nuclear reactor count-factor-increase time monitoring circuit which includes a pulse-type neutron detector, and means for counting the number of detected pulses during specific time periods. Counts are compared and the comparison is utilized to develop a reactor scram signal, if necessary

  18. Count-doubling time safety circuit

    Science.gov (United States)

    Rusch, Gordon K.; Keefe, Donald J.; McDowell, William P.

    1981-01-01

    There is provided a nuclear reactor count-factor-increase time monitoring circuit which includes a pulse-type neutron detector, and means for counting the number of detected pulses during specific time periods. Counts are compared and the comparison is utilized to develop a reactor scram signal, if necessary.

  19. A low-power timing discriminator for space instrumentation

    International Nuclear Information System (INIS)

    Devoto, P.; Medale, J.-L.; Aoustin, C.; Sauvaud, J.-A.

    2004-01-01

    A front-end electronics for three-dimensional time-of-flight space plasma analyzers has been developed. These mass spectrometers, allowing the determination of the distribution functions of the main ion species, are based on the selection of the ion energy per charge and arrival direction using an electrostatic analyzer, and on the determination of their velocity from the time separating a start and a stop pulse. The start pulse is provided by the collection on a microchannel plate (MCP) of secondary electrons emitted when each ion crosses a thin carbon foil. The stop pulse is provided by the ion hitting a second MCP. The aim of the electronics presented in this article is to process the signals provided by MCPs to generate logic pulses, allowing the measurement of precise time differences. The design consists of an amplifier and a timing discriminator which performs a timing compensation to eliminate the time walk. A first version of the circuit has been developed and achieves a time walk of ∼400 ps for an input amplitude dynamic range of 25 dB. The total power dissipation per channel is ∼14 mW at an event rate of 100 KHz and ∼19 mW at a rate of 1 MHz. The influence of the temperature on the circuit behavior has been investigated. The performances of the circuit in a complete detector were also evaluated. This circuit is designed to be used in various designs for future missions

  20. Neutron spectrum measurement using rise-time discrimination method

    International Nuclear Information System (INIS)

    Luo Zhiping; Suzuki, C.; Kosako, T.; Ma Jizeng

    2009-01-01

    PSD method can be used to measure the fast neutron spectrum in n/γ mixed field. A set of assemblies for measuring the pulse height distribution of neutrons is built up,based on a large volume NE213 liquid scintillator and standard NIM circuits,through the rise-time discrimination method. After that,the response matrix is calculated using Monte Carlo method. The energy calibration of the pulse height distribution is accomplished using 60 Co radioisotope. The neutron spectrum of the mono-energetic accelerator neutron source is achieved by unfolding process. Suggestions for further improvement of the system are presented at last. (authors)

  1. Four-deep charge-time and pulse-width scaling discriminator for delay line MWPC's

    International Nuclear Information System (INIS)

    Lee, K.L.; Kirsten, F.A.; Grigorian, A.; Guiragossian, Z.G.T.

    1976-01-01

    A discriminator has been developed for digitizing both intercepted total charge and location of electromagnetic shower and particle trajectories in multi-wire proportional chambers read by delay lines. Determination of shower trajectory is aided by video signal integration followed by centroid-locating discrimination. Calibrated run-down of the signal integrating capacitor gives the charge information above a given threshold level. The discriminator is designed to handle up to four shower-induced video signals per event by incorporating steering circuits within the module. Each video signal is examined for time over an adjustable threshold. Video pulses with separation of less than 20 nsec are treated as a single pulse. Counter-logic circuits indicate the number of video signals digitized. These signal processing circuits provide a first level of data sifting which otherwise must be carried out with additional discriminator channels and added complexity in data recognition

  2. Timing control by redundant inhibitory neuronal circuits

    Energy Technology Data Exchange (ETDEWEB)

    Tristan, I., E-mail: itristan@ucsd.edu; Rulkov, N. F.; Huerta, R.; Rabinovich, M. [BioCircuits Institute, University of California, San Diego, La Jolla, California 92093-0402 (United States)

    2014-03-15

    Rhythms and timing control of sequential activity in the brain is fundamental to cognition and behavior. Although experimental and theoretical studies support the understanding that neuronal circuits are intrinsically capable of generating different time intervals, the dynamical origin of the phenomenon of functionally dependent timing control is still unclear. Here, we consider a new mechanism that is related to the multi-neuronal cooperative dynamics in inhibitory brain motifs consisting of a few clusters. It is shown that redundancy and diversity of neurons within each cluster enhances the sensitivity of the timing control with the level of neuronal excitation of the whole network. The generality of the mechanism is shown to work on two different neuronal models: a conductance-based model and a map-based model.

  3. Timing control by redundant inhibitory neuronal circuits

    International Nuclear Information System (INIS)

    Tristan, I.; Rulkov, N. F.; Huerta, R.; Rabinovich, M.

    2014-01-01

    Rhythms and timing control of sequential activity in the brain is fundamental to cognition and behavior. Although experimental and theoretical studies support the understanding that neuronal circuits are intrinsically capable of generating different time intervals, the dynamical origin of the phenomenon of functionally dependent timing control is still unclear. Here, we consider a new mechanism that is related to the multi-neuronal cooperative dynamics in inhibitory brain motifs consisting of a few clusters. It is shown that redundancy and diversity of neurons within each cluster enhances the sensitivity of the timing control with the level of neuronal excitation of the whole network. The generality of the mechanism is shown to work on two different neuronal models: a conductance-based model and a map-based model

  4. An integral whole circuit of amplifying and discriminating suited to high counting rate

    International Nuclear Information System (INIS)

    Dong Chengfu; Su Hong; Wu Ming; Li Xiaogang; Peng Yu; Qian Yi; Liu Yicai; Xu Sijiu; Ma Xiaoli

    2007-01-01

    A hybrid circuit consists of charge sensitive preamplifier, main amplifier, discriminator and shaping circuit was described. This instrument has characteristics of low power consumption, small volume, high sensitivity, potable and so on, and is convenient for use in field. The output pulse of this instrument may directly consist with CMOS or TTL logic level. This instrument was mainly used for count measurement, for example, for high sensitive 3 He neutron detector, meanwhile also may used for other heavy ion detectors, the highest counting rate can reach 10 6 /s. (authors)

  5. Simulation Approach for Timing Analysis of Genetic Logic Circuits

    DEFF Research Database (Denmark)

    Baig, Hasan; Madsen, Jan

    2017-01-01

    in a manner similar to electronic logic circuits, but they are much more stochastic and hence much harder to characterize. In this article, we introduce an approach to analyze the threshold value and timing of genetic logic circuits. We show how this approach can be used to analyze the timing behavior...... of single and cascaded genetic logic circuits. We further analyze the timing sensitivity of circuits by varying the degradation rates and concentrations. Our approach can be used not only to characterize the timing behavior but also to analyze the timing constraints of cascaded genetic logic circuits...

  6. BiCMOS amplifier-discriminator integrated circuit for gas-filled detector readout

    International Nuclear Information System (INIS)

    Herve, C.; Dzahini, D.; Le Caer, T.; Richer, J.-P.; Torki, K.

    2005-01-01

    The paper presents a 16-channel amplifier-discriminator designed in BiCMOS technology. It will be used for the binary parallel readout of gas-filled detectors being designed at the European Synchrotron Radiation Facility. The circuit (named AMS211) has been manufactured. The measured transimpedance gain (400 KΩ), bandwidth (25 MHz) and noise (1570 e - +95 e - /pF ENC) well match the simulated results. The discriminator thresholds are individually controlled by built-in Digital to Analogue Converter. The experience gained with a first prototype of readout electronics indicates that the AMS211 should meet our requirements

  7. BiCMOS amplifier-discriminator integrated circuit for gas-filled detector readout

    Energy Technology Data Exchange (ETDEWEB)

    Herve, C. [European Synchrotron Radiation Facility, BP 220, 38043 Grenoble Cedex (France)]. E-mail: herve@esrf.fr; Dzahini, D. [Laboratoire de Physique Subatomique et de Cosmologie, Grenoble (France); Le Caer, T. [European Synchrotron Radiation Facility, BP 220, 38043 Grenoble Cedex (France); Richer, J.-P. [Laboratoire de Physique Subatomique et de Cosmologie, Grenoble (France); Torki, K. [Laboratoire TIMA, Grenoble (France)

    2005-03-21

    The paper presents a 16-channel amplifier-discriminator designed in BiCMOS technology. It will be used for the binary parallel readout of gas-filled detectors being designed at the European Synchrotron Radiation Facility. The circuit (named AMS211) has been manufactured. The measured transimpedance gain (400 K{omega}), bandwidth (25 MHz) and noise (1570 e{sup -}+95 e{sup -}/pF ENC) well match the simulated results. The discriminator thresholds are individually controlled by built-in Digital to Analogue Converter. The experience gained with a first prototype of readout electronics indicates that the AMS211 should meet our requirements.

  8. Optimal planning of series resistor to control time constant of test circuit for high-voltage AC circuit-breakers

    OpenAIRE

    Yoon-Ho Kim; Jung-Hyeon Ryu; Jin-Hwan Kim; Kern-Joong Kim

    2016-01-01

    The equivalent test circuit that can deliver both short-circuit current and recovery voltage is used to verify the performance of high-voltage circuit breakers. Most of the parameters in this circuit can be obtained by using a simple calculation or a simulation program. The ratings of the circuit breaker include rated short-circuit breaking current, rated short-circuit making current, rated operating sequence of the circuit breaker and rated short-time current. Among these ratings, the short-...

  9. A time-to-amplitude converter with constant fraction timing discriminators for short time interval measurements

    International Nuclear Information System (INIS)

    Kostamovaara, J.; Myllylae, R.

    1985-01-01

    The construction and the performance of a time-to-amplitude converter equipped with constant fraction discriminators is described. The TAC consists of digital and analog parts which are constructed on two printed circuit boards, both of which are located in a single width NIM module. The dead time of the TAC for a start pulse which is not followed by a stop pulse within the time range of the device (proportional100 ns) is only proportional100 ns, which enables one to avoid counting rate saturation even with a high random input signal rate. The differential and integral nonlinearities of the TAC are better than +-1.5% and 0.05%, respectively. The resolution for input timing pulses of constant shape is 20 ps (fwhm), and less than 10 ps (fwhm) with a modification in the digital part. The walk error of the constant fraction timing discriminators is presented and various parameters affecting it are discussed. The effect of the various disturbances in linearity caused by the fast ECL logic and their minimization are also discussed. The time-to-amplitude converter has been used in positron lifetime studies and for laser range finding. (orig.)

  10. Real time automatic discriminating of ultrasonic flaws

    International Nuclear Information System (INIS)

    Suhairy Sani; Mohd Hanif Md Saad; Marzuki Mustafa; Mohd Redzwan Rosli

    2009-01-01

    This paper is concerned with the real time automatic discriminating of flaws from two categories; i. cracks (planar defect) and ii. Non-cracks (volumetric defect such as cluster porosity and slag) using pulse-echo ultrasound. The raw ultrasonic flaws signal were collected from a computerized robotic plane scanning system over the whole of each reflector as the primary source of data. The signal is then filtered and the analysis in both time and frequency domain were executed to obtain the selected feature. The real time feature analysis techniques measured the number of peaks, maximum index, pulse duration, rise time and fall time. The obtained features could be used to distinguish between quantitatively classified flaws by using various tools in artificial intelligence such as neural networks. The proposed algorithm and complete system were implemented in a computer software developed using Microsoft Visual BASIC 6.0 (author)

  11. Timing Analysis of Genetic Logic Circuits using D-VASim

    DEFF Research Database (Denmark)

    Baig, Hasan; Madsen, Jan

    and propagation delay analysis of single as well as cascaded geneticlogic circuits can be performed. D-VASim allows user to change the circuit parameters during runtime simulation to observe its effectson circuit’s timing behavior. The results obtained from D-VASim can be used not only to characterize the timing...... delay analysis may play a very significant role in the designing of genetic logic circuits. In thisdemonstration, we present the capability of D-VASim (Dynamic Virtual Analyzer and Simulator) to perform the timing and propagationdelay analysis of genetic logic circuits. Using D-VASim, the timing...... behavior of geneticlogic circuits but also to analyze the timing constraints of cascaded genetic logic circuits....

  12. Hybrid integrated circuit for charge-to-time interval conversion

    Energy Technology Data Exchange (ETDEWEB)

    Basiladze, S.G.; Dotsenko, Yu.Yu.; Man' yakov, P.K.; Fedorchenko, S.N. (Joint Inst. for Nuclear Research, Dubna (USSR))

    The hybrid integrated circuit for charge-to time interval conversion with nanosecond input fast response is described. The circuit can be used in energy measuring channels, time-to-digital converters and in the modified variant in amplitude-to-digital converters. The converter described consists of a buffer amplifier, a linear transmission circuit, a direct current source and a unit of time interval separation. The buffer amplifier represents a current follower providing low input and high output resistances by the current feedback. It is concluded that the described converter excelled the QT100B circuit analogous to it in a number of parameters especially, in thermostability.

  13. Minimizing time for test in integrated circuit

    OpenAIRE

    Andonova, A. S.; Dimitrov, D. G.; Atanasova, N. G.

    2004-01-01

    The cost for testing integrated circuits represents a growing percentage of the total cost for their production. The former strictly depends on the length of the test session, and its reduction has been the target of many efforts in the past. This paper proposes a new method for reducing the test length by adopting a new architecture and exploiting an evolutionary optimisation algorithm. A prototype of the proposed approach was tested on 1SCAS standard benchmarks and theexperimental results s...

  14. Optical timing receiver for the NASA Spaceborne Ranging System. Part I. Dual peak-sensing timing discriminator

    International Nuclear Information System (INIS)

    Leskovar, B.; Lo, C.C.; Zizka, G.

    1978-01-01

    Position-resolution capabilities of the NASA Spaceborne Laser Ranging System are essentially determined by the time-resolution capabilities of its optical timing receiver. The optical timing receiver consists of a fast photoelectric device; (e.g., photomultiplier or an avalanche photodiode detector), a timing discriminator, a high-precision event-timing digitizer, and a signal-processing system. The time-resolution capabilities of the receiver are determined by the photoelectron time spread of the photoelectric device, the time walk and resolution characteristics of the timing discriminator, and the resolution of the event-timing digitizer. It is thus necessary to evaluate available fast photoelectronic devices with respect to their time-resolution capabilities, to design a very low time walk timing discriminator and to develop a high-resolution event-timing digitizer which will be used in the high-resolution spaceborne laser ranging system receiver. The development of a new dual-peak sensing timing discriminator is described. The amplitude dependent time walk is less than +-150 psec for a 100:1 dynamic range of Gaussian-shaped input signals having pulse widths between 11 and 17 nsec. The unit produces 800 mV negative output pulses, each 10 nsec wide, and 3V positive pulses with widths of 15 nsec. The time delay through the discriminator is approximately 37 nsec. In this discriminator the input signal is processed by a peak-crossing circuit which produces a bipolar pulse having its zero-crossing point at the peak of the input signal. All essential functions in the discriminator are performed by means of tunnel diodes with backward diodes as nonlinear loads. The discriminator is designed to be CAMAC compatible to a conventional time-interval unit or a high-precision event timing digitizer. The adjustment procedure for obtaining minimum time walk is also given

  15. Time series analysis in chaotic diode resonator circuit

    Energy Technology Data Exchange (ETDEWEB)

    Hanias, M.P. [TEI of Chalkis, GR 34400, Evia, Chalkis (Greece)] e-mail: mhanias@teihal.gr; Giannaris, G. [TEI of Chalkis, GR 34400, Evia, Chalkis (Greece); Spyridakis, A. [TEI of Chalkis, GR 34400, Evia, Chalkis (Greece); Rigas, A. [TEI of Chalkis, GR 34400, Evia, Chalkis (Greece)

    2006-01-01

    A diode resonator chaotic circuit is presented. Multisim is used to simulate the circuit and show the presence of chaos. Time series analysis performed by the method proposed by Grasberger and Procaccia. The correlation and minimum embedding dimension {nu} and m {sub min}, respectively, were calculated. Also the corresponding Kolmogorov entropy was calculated.

  16. Time series analysis in chaotic diode resonator circuit

    International Nuclear Information System (INIS)

    Hanias, M.P.; Giannaris, G.; Spyridakis, A.; Rigas, A.

    2006-01-01

    A diode resonator chaotic circuit is presented. Multisim is used to simulate the circuit and show the presence of chaos. Time series analysis performed by the method proposed by Grasberger and Procaccia. The correlation and minimum embedding dimension ν and m min , respectively, were calculated. Also the corresponding Kolmogorov entropy was calculated

  17. A METHOD AND AN APPARATUS FOR PROVIDING TIMING SIGNALS TO A NUMBER OF CIRCUITS, AN INTEGRATED CIRCUIT AND A NODE

    DEFF Research Database (Denmark)

    2006-01-01

    A method of providing or transporting a timing signal between a number of circuits, electrical or optical, where each circuit is fed by a node. The nodes forward timing signals between each other, and at least one node is adapted to not transmit a timing signal before having received a timing...... signal from at least two nodes. In this manner, the direction of the timing skew between nodes and circuits is known and data transport between the circuits made easier....

  18. Space Time – Track Circuits with Trellis Code Modulation

    Directory of Open Access Journals (Sweden)

    Marius Enulescu

    2017-07-01

    Full Text Available The track circuits are very important equipments used in the railway transportation system. Today these are used to send vital information, to the running train, in the same time with the integrity checking of the rail. The actual track circuits have a small problem due to the use of the same transmission medium by the signals containing vital information and the return traction current, the running track rails. But this small problem can produce big disturbances in the train circulation, especially in the rush hours. To improve the data transmission to the train on-board equipment, the implementation of new track circuits using new communication technology were studied. This technology is used by the mobile and satellite communications and applies the principle of diversity encoding both time and space through the use of multiple transmission points of the track circuit signal for telegram which is sent to the train. Since this implementation does not satisfy the intended purpose, other modern communication principles such as 8PSK signals modulation and encoding using Trellis Coded Modulation were developed. This new track circuit aims to solve the problems which appeared in the current operation of track circuits and theoretically manages to transmit vital information to the train on board equipment without being affected by disturbances in electric traction transport systems.

  19. Differential discriminator

    International Nuclear Information System (INIS)

    Dukhanov, V.I.; Mazurov, I.B.

    1981-01-01

    A principal flowsheet of a differential discriminator intended for operation in a spectrometric circuit with statistical time distribution of pulses is described. The differential discriminator includes four integrated discriminators and a channel of piled-up signal rejection. The presence of the rejection channel enables the discriminator to operate effectively at loads of 14x10 3 pulse/s. The temperature instability of the discrimination thresholds equals 250 μV/ 0 C. The discrimination level changes within 0.1-5 V, the level shift constitutes 0.5% for the filling ratio of 1:10. The rejection coefficient is not less than 90%. Alpha spectrum of the 228 Th source is presented to evaluate the discriminator operation with the rejector. The rejector provides 50 ns time resolution

  20. Fault diagnosis for analog circuits utilizing time-frequency features and improved VVRKFA

    Science.gov (United States)

    He, Wei; He, Yigang; Luo, Qiwu; Zhang, Chaolong

    2018-04-01

    This paper proposes a novel scheme for analog circuit fault diagnosis utilizing features extracted from the time-frequency representations of signals and an improved vector-valued regularized kernel function approximation (VVRKFA). First, the cross-wavelet transform is employed to yield the energy-phase distribution of the fault signals over the time and frequency domain. Since the distribution is high-dimensional, a supervised dimensionality reduction technique—the bilateral 2D linear discriminant analysis—is applied to build a concise feature set from the distributions. Finally, VVRKFA is utilized to locate the fault. In order to improve the classification performance, the quantum-behaved particle swarm optimization technique is employed to gradually tune the learning parameter of the VVRKFA classifier. The experimental results for the analog circuit faults classification have demonstrated that the proposed diagnosis scheme has an advantage over other approaches.

  1. Pneumatic oscillator circuits for timing and control of integrated microfluidics.

    Science.gov (United States)

    Duncan, Philip N; Nguyen, Transon V; Hui, Elliot E

    2013-11-05

    Frequency references are fundamental to most digital systems, providing the basis for process synchronization, timing of outputs, and waveform synthesis. Recently, there has been growing interest in digital logic systems that are constructed out of microfluidics rather than electronics, as a possible means toward fully integrated laboratory-on-a-chip systems that do not require any external control apparatus. However, the full realization of this goal has not been possible due to the lack of on-chip frequency references, thus requiring timing signals to be provided from off-chip. Although microfluidic oscillators have been demonstrated, there have been no reported efforts to characterize, model, or optimize timing accuracy, which is the fundamental metric of a clock. Here, we report pneumatic ring oscillator circuits built from microfluidic valves and channels. Further, we present a compressible-flow analysis that differs fundamentally from conventional circuit theory, and we show the utility of this physically based model for the optimization of oscillator stability. Finally, we leverage microfluidic clocks to demonstrate circuits for the generation of phase-shifted waveforms, self-driving peristaltic pumps, and frequency division. Thus, pneumatic oscillators can serve as on-chip frequency references for microfluidic digital logic circuits. On-chip clocks and pumps both constitute critical building blocks on the path toward achieving autonomous laboratory-on-a-chip devices.

  2. Pulse-width discriminators

    International Nuclear Information System (INIS)

    Budyashov, Yu.G.; Grebenyuk, V.M.; Zinov, V.G.

    1978-01-01

    A pulse duration discriminator is described which is intended for processing signals from multilayer scintillators. The basic elements of the scintillator are: an input gate, a current generator, an integrating capacitor, a Schmidt trigger and an anticoincidence circuit. The basic circuit of the discriminator and its time diagrams explaining its operating are given. The discriminator is based on microcircuits. Pulse duration discrimination threshold changes continuously from 20 to 100 ns, while its amplitude threshold changes within 20 to 100 mV. The temperature instability of discrimination thresholds (both in pulse width and in amplitude) is better than 0.1 per cent/deg C

  3. Time- and Site-Resolved Dynamics in a Topological Circuit

    Directory of Open Access Journals (Sweden)

    Jia Ningyuan

    2015-06-01

    Full Text Available From studies of exotic quantum many-body phenomena to applications in spintronics and quantum information processing, topological materials are poised to revolutionize the condensed-matter frontier and the landscape of modern materials science. Accordingly, there is a broad effort to realize topologically nontrivial electronic and photonic materials for fundamental science as well as practical applications. In this work, we demonstrate the first simultaneous site- and time-resolved measurements of a time-reversal-invariant topological band structure, which we realize in a radio-frequency photonic circuit. We control band-structure topology via local permutation of a traveling-wave capacitor-inductor network, increasing robustness by going beyond the tight-binding limit. We observe a gapped density of states consistent with a modified Hofstadter spectrum at a flux per plaquette of ϕ=π/2. In situ probes of the band gaps reveal spatially localized bulk states and delocalized edge states. Time-resolved measurements reveal dynamical separation of localized edge excitations into spin-polarized currents. The radio-frequency circuit paradigm is naturally compatible with nonlocal coupling schemes, allowing us to implement a Möbius strip topology inaccessible in conventional systems. This room-temperature experiment illuminates the origins of topology in band structure, and when combined with circuit quantum electrodynamics techniques, it provides a direct path to topologically ordered quantum matter.

  4. Multi-Channel Amplifier-Discriminator for Highly Time-Resolved Detection

    CERN Document Server

    Despeisse, M; Lapington, J; Jarron, P

    2011-01-01

    A low-power multi-channel amplifier-discriminator was developed for application in highly time-resolved detection systems. The proposed circuit architecture, so-called Nino, is based on a time-over-threshold approach and shows a high potential for time-resolved readout of solid-state photo-detectors and of detectors based on vacuum technologies. The Irpics circuit was designed in a 250 nm CMOS technology, implementing 32 channels of a Nino version optimized to achieve high-time resolution on the output low-voltage differential signals (LVDS) while keeping a low power consumption of 10 mW per channel. Electrical characterizations of the circuit demonstrate a very low intrinsic time jitter on the output pulse leading edge, measured below 10 ps rms for each channel for high input signal charges (100 fC) and below 25 ps rms for low input signal charges (20-100 fC). The read-out architecture moreover permits to retrieve the input signal charge from the timing measurements, while a calibration procedure was develop...

  5. An analytical approach to bistable biological circuit discrimination using real algebraic geometry.

    Science.gov (United States)

    Siegal-Gaskins, Dan; Franco, Elisa; Zhou, Tiffany; Murray, Richard M

    2015-07-06

    Biomolecular circuits with two distinct and stable steady states have been identified as essential components in a wide range of biological networks, with a variety of mechanisms and topologies giving rise to their important bistable property. Understanding the differences between circuit implementations is an important question, particularly for the synthetic biologist faced with determining which bistable circuit design out of many is best for their specific application. In this work we explore the applicability of Sturm's theorem--a tool from nineteenth-century real algebraic geometry--to comparing 'functionally equivalent' bistable circuits without the need for numerical simulation. We first consider two genetic toggle variants and two different positive feedback circuits, and show how specific topological properties present in each type of circuit can serve to increase the size of the regions of parameter space in which they function as switches. We then demonstrate that a single competitive monomeric activator added to a purely monomeric (and otherwise monostable) mutual repressor circuit is sufficient for bistability. Finally, we compare our approach with the Routh-Hurwitz method and derive consistent, yet more powerful, parametric conditions. The predictive power and ease of use of Sturm's theorem demonstrated in this work suggest that algebraic geometric techniques may be underused in biomolecular circuit analysis.

  6. Discriminator/time interval meter system evaluation report

    International Nuclear Information System (INIS)

    Condreva, K.J.

    1976-01-01

    The purpose of this report is to discuss the evaluation of a modular prototype Discriminator/Time Interval Meter data acquisition unit as a useful tool in a digital diagnostics system. The characteristics, operation and calibration of each of the hardware components are discussed in some detail. A discussion of the system calibration, operation, and data ingestion and reduction is also given. System test results to date are given and discussed. Finally, recommendations and conclusions concerning the capabilities of the Discriminator/T.I.M. system based on test and calibration results to date are given

  7. Discriminator/time interval meter system evaluation report

    Energy Technology Data Exchange (ETDEWEB)

    Condreva, K. J.

    1976-04-12

    The purpose of this report is to discuss the evaluation of a modular prototype Discriminator/Time Interval Meter data acquisition unit as a useful tool in a digital diagnostics system. The characteristics, operation and calibration of each of the hardware components are discussed in some detail. A discussion of the system calibration, operation, and data ingestion and reduction is also given. System test results to date are given and discussed. Finally, recommendations and conclusions concerning the capabilities of the Discriminator/T.I.M. system based on test and calibration results to date are given.

  8. A Circuit Model of Real Time Human Body Hydration.

    Science.gov (United States)

    Asogwa, Clement Ogugua; Teshome, Assefa K; Collins, Stephen F; Lai, Daniel T H

    2016-06-01

    Changes in human body hydration leading to excess fluid losses or overload affects the body fluid's ability to provide the necessary support for healthy living. We propose a time-dependent circuit model of real-time human body hydration, which models the human body tissue as a signal transmission medium. The circuit model predicts the attenuation of a propagating electrical signal. Hydration rates are modeled by a time constant τ, which characterizes the individual specific metabolic function of the body part measured. We define a surrogate human body anthropometric parameter θ by the muscle-fat ratio and comparing it with the body mass index (BMI), we find theoretically, the rate of hydration varying from 1.73 dB/min, for high θ and low τ to 0.05 dB/min for low θ and high τ. We compare these theoretical values with empirical measurements and show that real-time changes in human body hydration can be observed by measuring signal attenuation. We took empirical measurements using a vector network analyzer and obtained different hydration rates for various BMI, ranging from 0.6 dB/min for 22.7 [Formula: see text] down to 0.04 dB/min for 41.2 [Formula: see text]. We conclude that the galvanic coupling circuit model can predict changes in the volume of the body fluid, which are essential in diagnosing and monitoring treatment of body fluid disorder. Individuals with high BMI would have higher time-dependent biological characteristic, lower metabolic rate, and lower rate of hydration.

  9. Electronic circuit encyclopedia 2

    International Nuclear Information System (INIS)

    Park, Sun Ho

    1992-10-01

    This book is composed of 15 chapters, which are amplification of weak signal and measurement circuit audio control and power amplification circuit, data transmission and wireless system, forwarding and isolation, signal converting circuit, counter and comparator, discriminator circuit, oscillation circuit and synthesizer, digital and circuit on computer image processing circuit, sensor drive circuit temperature sensor circuit, magnetic control and application circuit, motor driver circuit, measuring instrument and check tool and power control and stability circuit.

  10. Electronic circuit encyclopedia 2

    Energy Technology Data Exchange (ETDEWEB)

    Park, Sun Ho

    1992-10-15

    This book is composed of 15 chapters, which are amplification of weak signal and measurement circuit audio control and power amplification circuit, data transmission and wireless system, forwarding and isolation, signal converting circuit, counter and comparator, discriminator circuit, oscillation circuit and synthesizer, digital and circuit on computer image processing circuit, sensor drive circuit temperature sensor circuit, magnetic control and application circuit, motor driver circuit, measuring instrument and check tool and power control and stability circuit.

  11. Numerical counting ratemeter with variable time constant and integrated circuits

    International Nuclear Information System (INIS)

    Kaiser, J.; Fuan, J.

    1967-01-01

    We present here the prototype of a numerical counting ratemeter which is a special version of variable time-constant frequency meter (1). The originality of this work lies in the fact that the change in the time constant is carried out automatically. Since the criterion for this change is the accuracy in the annunciated result, the integration time is varied as a function of the frequency. For the prototype described in this report, the time constant varies from 1 sec to 1 millisec. for frequencies in the range 10 Hz to 10 MHz. This prototype is built entirely of MECL-type integrated circuits from Motorola and is thus contained in two relatively small boxes. (authors) [fr

  12. Low-threshold amplitude discriminator circuit with tunnel diode and two transistors in differential connection

    International Nuclear Information System (INIS)

    Ryba, J.; Volny, J.

    1973-01-01

    The connection is designed of a low-threshold amplitude discriminator and a tunnel diode with two transistors in differential connection. The discriminator is by its simple connection, its low consumption and high temperature stability suitable especially for portable radiation detectors. The tunnel diode is connected by one pole to a collector clamp and by the other to the supply voltage. A suitable resistor is connected in parallel with the tunnel diode to meet demands for higher sensitivity. (Z.S.)

  13. The time course of shape discrimination in the human brain.

    Science.gov (United States)

    Ales, Justin M; Appelbaum, L Gregory; Cottereau, Benoit R; Norcia, Anthony M

    2013-02-15

    The lateral occipital cortex (LOC) activates selectively to images of intact objects versus scrambled controls, is selective for the figure-ground relationship of a scene, and exhibits at least some degree of invariance for size and position. Because of these attributes, it is considered to be a crucial part of the object recognition pathway. Here we show that human LOC is critically involved in perceptual decisions about object shape. High-density EEG was recorded while subjects performed a threshold-level shape discrimination task on texture-defined figures segmented by either phase or orientation cues. The appearance or disappearance of a figure region from a uniform background generated robust visual evoked potentials throughout retinotopic cortex as determined by inverse modeling of the scalp voltage distribution. Contrasting responses from trials containing shape changes that were correctly detected (hits) with trials in which no change occurred (correct rejects) revealed stimulus-locked, target-selective activity in the occipital visual areas LOC and V4 preceding the subject's response. Activity that was locked to the subjects' reaction time was present in the LOC. Response-locked activity in the LOC was determined to be related to shape discrimination for several reasons: shape-selective responses were silenced when subjects viewed identical stimuli but their attention was directed away from the shapes to a demanding letter discrimination task; shape-selectivity was present across four different stimulus configurations used to define the figure; LOC responses correlated with participants' reaction times. These results indicate that decision-related activity is present in the LOC when subjects are engaged in threshold-level shape discriminations. Copyright © 2012 Elsevier Inc. All rights reserved.

  14. Testing for time-based correlates of perceived gender discrimination.

    Science.gov (United States)

    Blau, Gary; Tatum, Donna Surges; Ward-Cook, Kory; Dobria, Lidia; McCoy, Keith

    2005-01-01

    Using a sample of 201 medical technologists (MTs) over a five-year period, this study extends initial findings on perceived gender discrimination (PGD) by Blau and Tatum (2000) by applying organizational justice variables and internal-external locus of control as hypothesized correlates of PGD. Three types of organizational justice were measured: distributive, procedural, and interactional. General relationships found include locus of control being related to PGD such that internals perceived lower PGD. Also, distributive, procedural, and interactional justice were negatively related to PGD. However, increasing the time interval between these correlates weakened their relationships. The relationship of interactional justice to PGD remained the most "resistant" to attenuation over time.

  15. Low-Power Amplifier-Discriminators for High Time Resolution Detection

    CERN Document Server

    Despeisse, M; Anghinolfi, F; Tiuraniemi, S; Osmic, F; Riedler, P; Kluge, A; Ceccucci, A

    2009-01-01

    Low-power amplifier-discriminators based on a so-called NINO architecture have been developed with high time resolution for the readout of radiation detectors. Two different circuits were integrated in the NINO13 chip, processed in IBM 130 nm CMOS technology. The LCO version (Low Capacitance and consumption Optimization) was designed for potential use as front-end electronics in the Gigatracker of the NA62 experiment at CERN. It was developed as pixel readout for solid-state pixel detectors to permit minimum ionizing particle detection with less than 180 ps rms resolution per pixel on the output pulse, for power consumption below 300 mu W per pixel. The HCO version (High Capacitance Optimization) was designed with 4 mW power consumption per channel to provide timing resolution below 20 ps rms on the output pulse, for charges above 10 fC. Results presented show the potential of the LCO and HCO circuits for the precise timing readout of solid-state detectors, vacuum tubes or gas detectors, for applications in h...

  16. Timing of Pulsed Prompt Gamma Rays for Background Discrimination

    International Nuclear Information System (INIS)

    Hueso-Gonzalez, F.; Golnik, C.; Berthel, M.; Dreyer, A.; Kormoll, T.; Rohling, H.; Pausch, G.; Enghardt, W.; Fiedler, F.; Heidel, K.; Schoene, S.; Schwengner, R.; Wagner, A.

    2013-06-01

    In the context of particle therapy, particle range verification is a major challenge for the quality assurance of the treatment. One approach is the measurement of the prompt gamma rays resulting from the tissue irradiation. A Compton camera based on several planes of position sensitive gamma ray detectors, together with an imaging algorithm, is expected to reconstruct the prompt gamma ray emission density profile, which is correlated with the dose distribution. At Helmholtz- Zentrum Dresden-Rossendorf (HZDR) and OncoRay, a camera prototype has been developed consisting of two scatter planes (CdZnTe cross strip detectors) and an absorber plane (Lu 2 SiO 5 block detector). The data acquisition is based on VME electronics and handled by software developed on the ROOT platform. The prototype was tested at the linear electron accelerator ELBE at HZDR, which was set up to produce bunched bremsstrahlung photons. Their spectrum has similarities with the one expected from prompt gamma rays in the clinical case, and these are also bunched with the accelerator frequency. The time correlation between the pulsed prompt photons and the measured signals was used for background discrimination, achieving a time resolution of 3 ns (2 ns) FWHM for the CZT (LSO) detector. A time-walk correction was applied for the LSO detector and improved its resolution to 1 ns. In conclusion, the detectors are suitable for time-resolved background discrimination in pulsed clinical particle accelerators. Ongoing tasks are the test of the imaging algorithms and the quantitative comparison with simulations. Further experiments will be performed at proton accelerators. (authors)

  17. Monolitic integrated circuit for the strobed charge-to-time converter

    International Nuclear Information System (INIS)

    Bel'skij, V.I.; Bushnin, Yu.B.; Zimin, S.A.; Punzhin, Yu.N.; Sen'ko, V.A.; Soldatov, M.M.; Tokarchuk, V.P.

    1985-01-01

    The developed and comercially produced semiconducting circuit - gating charge-to-time converter KR1101PD1 is described. The considered integrated circuit is a short pulse charge-to-time converter with integration of input current. The circuit is designed for construction of time-to-pulse analog-to-digital converters utilized in multichannel detection systems when studying complex topology processes. Input resistance of the circuit is 0.1 Ω permissible input current is 50 mA, maximum measured charge is 300-1000 pC

  18. Hopf bifurcation analysis of Chen circuit with direct time delay feedback

    International Nuclear Information System (INIS)

    Hai-Peng, Ren; Wen-Chao, Li; Ding, Liu

    2010-01-01

    Direct time delay feedback can make non-chaotic Chen circuit chaotic. The chaotic Chen circuit with direct time delay feedback possesses rich and complex dynamical behaviours. To reach a deep and clear understanding of the dynamics of such circuits described by delay differential equations, Hopf bifurcation in the circuit is analysed using the Hopf bifurcation theory and the central manifold theorem in this paper. Bifurcation points and bifurcation directions are derived in detail, which prove to be consistent with the previous bifurcation diagram. Numerical simulations and experimental results are given to verify the theoretical analysis. Hopf bifurcation analysis can explain and predict the periodical orbit (oscillation) in Chen circuit with direct time delay feedback. Bifurcation boundaries are derived using the Hopf bifurcation analysis, which will be helpful for determining the parameters in the stabilisation of the originally chaotic circuit

  19. Time resolution studies using digital constant fraction discrimination

    International Nuclear Information System (INIS)

    Fallu-Labruyere, A.; Tan, H.; Hennig, W.; Warburton, W.K.

    2007-01-01

    Digital Pulse Processing (DPP) modules are being increasingly considered to replace modular analog electronics in medium-scale nuclear physics experiments (100-1000s of channels). One major area remains, however, where it has not been convincingly demonstrated that DPP modules are competitive with their analog predecessors-time-of-arrival measurement. While analog discriminators and time-to-amplitude converters can readily achieve coincidence time resolutions in the 300-500 ps range with suitably fast scintillators and Photomultiplier Tubes (PMTs), this capability has not been widely demonstrated with DPPs. Some concern has been expressed, in fact, that such time resolutions are attainable with the 10 ns sampling times that are presently commonly available. In this work, we present time-coincidence measurements taken using a commercially available DPP (the Pixie-4 from XIA LLC) directly coupled to pairs of fast PMTs mated with either LSO or LaBr 3 scintillator crystals and excited by 22 Na γ-ray emissions. Our results, 886 ps for LSO and 576 ps for LaBr 3 , while not matching the best literature results using analog electronics, are already well below 1 ns and fully adequate for a wide variety of experiments. These results are shown not to be limited by the DPPs themselves, which achieved 57 ps time resolution using a pulser, but are degraded in part both by the somewhat limited number of photoelectrons we collected and by a sub-optimum choice of PMT. Analysis further suggests that increasing the sampling speed would further improve performance. We therefore conclude that DPP time-of-arrival resolution is already adequate to supplant analog processing in many applications and that further improvements could be achieved with only modest efforts

  20. Abnormal hubs of white matter networks in the frontal-parieto circuit contribute to depression discrimination via pattern classification.

    Science.gov (United States)

    Qin, Jiaolong; Wei, Maobin; Liu, Haiyan; Chen, Jianhuai; Yan, Rui; Hua, Lingling; Zhao, Ke; Yao, Zhijian; Lu, Qing

    2014-12-01

    Previous studies had explored the diagnostic and prognostic value of the structural neuroimaging data of MDD and treated the whole brain voxels, the fractional anisotropy and the structural connectivity as classification features. To our best knowledge, no study examined the potential diagnostic value of the hubs of anatomical brain networks in MDD. The purpose of the current study was to provide an exploratory examination of the potential diagnostic and prognostic values of hubs of white matter brain networks in MDD discrimination and the corresponding impaired hub pattern via a multi-pattern analysis. We constructed white matter brain networks from 29 depressions and 30 healthy controls based on diffusion tensor imaging data, calculated nodal measures and identified hubs. Using these measures as features, two types of feature architectures were established, one only included hubs (HUB) and the other contained both hubs and non hubs. The support vector machine classifiers with Gaussian radial basis kernel were used after the feature selection. Moreover, the relative contribution of the features was estimated by means of the consensus features. Our results presented that the hubs (including the bilateral dorsolateral part of superior frontal gyrus, the left middle frontal gyrus, the bilateral middle temporal gyrus, and the bilateral inferior temporal gyrus) played an important role in distinguishing the depressions from healthy controls with the best accuracy of 83.05%. Moreover, most of the HUB consensus features located in the frontal-parieto circuit. These findings provided evidence that the hubs could be served as valuable potential diagnostic measure for MDD, and the hub-concentrated lesion distribution of MDD was primarily anchored within the frontal-parieto circuit. Copyright © 2014 Elsevier Inc. All rights reserved.

  1. Chaos in Electronic Circuits: Nonlinear Time Series Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Wheat, Jr., Robert M. [Kennedy Western Univ., Cheyenne, WY (United States)

    2003-07-01

    Chaos in electronic circuits is a phenomenon that has been largely ignored by engineers, manufacturers, and researchers until the early 1990’s and the work of Chua, Matsumoto, and others. As the world becomes more dependent on electronic devices, the detrimental effects of non-normal operation of these devices becomes more significant. Developing a better understanding of the mechanisms involved in the chaotic behavior of electronic circuits is a logical step toward the prediction and prevention of any potentially catastrophic occurrence of this phenomenon. Also, a better understanding of chaotic behavior, in a general sense, could potentially lead to better accuracy in the prediction of natural events such as weather, volcanic activity, and earthquakes. As a first step in this improvement of understanding, and as part of the research being reported here, methods of computer modeling, identifying and analyzing, and producing chaotic behavior in simple electronic circuits have been developed. The computer models were developed using both the Alternative Transient Program (ATP) and Spice, the analysis techniques have been implemented using the C and C++ programming languages, and the chaotically behaving circuits developed using “off the shelf” electronic components.

  2. Statistical timing for parametric yield prediction of digital integrated circuits

    NARCIS (Netherlands)

    Jess, J.A.G.; Kalafala, K.; Naidu, S.R.; Otten, R.H.J.M.; Visweswariah, C.

    2006-01-01

    Uncertainty in circuit performance due to manufacturing and environmental variations is increasing with each new generation of technology. It is therefore important to predict the performance of a chip as a probabilistic quantity. This paper proposes three novel path-based algorithms for statistical

  3. Studies of the LBL CMOS integrated amplifier/discriminator for randomly timed inputs from fixed target experiments

    International Nuclear Information System (INIS)

    Russ, J.S.; Yarema, R.J.; Zimmerman, T.

    1988-12-01

    A group at Lawrence Berkeley Laboratory has reported an elegant CMOS VLSI circuit for amplifying, discriminating, and encoding the signals from highly-segmented charge output devices, e.g., silicon strip detectors or pad readout structures in gaseous detectors. The design exploits switched capacitor circuits and the well-known time structure of data acquisition in colliding beam accelerators to cancel leakage effects and switching noise. For random inputs, these methods are not directly applicable. However, the high speed of the reset switches makes possible a mode of operation for fixed target experiments that uses fast resets to erase unwanted data from random triggers. Data acquisition in this mode has been performed. Details of operation and measurements of noise and rate capability will be presented. 8 refs., 6 figs

  4. Perceived Interpersonal Discrimination and Older Women’s Mental Health: Accumulation Across Domains, Attributions, and Time

    Science.gov (United States)

    Bécares, Laia; Zhang, Nan

    2018-01-01

    Abstract Experiencing discrimination is associated with poor mental health, but how cumulative experiences of perceived interpersonal discrimination across attributes, domains, and time are associated with mental disorders is still unknown. Using data from the Study of Women’s Health Across the Nation (1996–2008), we applied latent class analysis and generalized linear models to estimate the association between cumulative exposure to perceived interpersonal discrimination and older women’s mental health. We found 4 classes of perceived interpersonal discrimination, ranging from cumulative exposure to discrimination over attributes, domains, and time to none or minimal reports of discrimination. Women who experienced cumulative perceived interpersonal discrimination over time and across attributes and domains had the highest risk of depression (Center for Epidemiologic Studies Depression Scale score ≥16) compared with women in all other classes. This was true for all women regardless of race/ethnicity, although the type and severity of perceived discrimination differed across racial/ethnic groups. Cumulative exposure to perceived interpersonal discrimination across attributes, domains, and time has an incremental negative long-term association with mental health. Studies that examine exposure to perceived discrimination due to a single attribute in 1 domain or at 1 point in time underestimate the magnitude and complexity of discrimination and its association with health. PMID:29036550

  5. Time resolution measurements with an improved discriminator and conical scintillators

    International Nuclear Information System (INIS)

    McGervey, J.D.; Vogel, J.; Sen, P.; Knox, C.

    1977-01-01

    A new constant fraction discriminator with improved stability and walk characteristics is described. The discriminator was used with RCA C31024 photomultiplier tubes to test scintillators of conical and cylindrical shapes. Conical scintillators of 2.54 cm base diameter, 1.0 cm top diameter, and 2.54 cm height gave a fwhm of 155 ps for 60 Co gamma rays; larger conical scintillators gave an improvement of 10-15% in fwhm over cylindrical scintillators of equal volume. (Auth.)

  6. Dead time effects from linear amplifiers and discriminators in single detector systems

    International Nuclear Information System (INIS)

    Funck, E.

    1986-01-01

    The dead-time losses originating from a linear amplifier combined with a discriminator for pulse-height selection are investigated. Measurements are carried out to determine the type of dead time represented by the amplifier-discriminator combination. The corrections involved by feeding the discriminator output pulses into an electronic module producing a blocking time are discussed and practical hints are given to reduce them. (orig.)

  7. High frequency, high time resolution time-to-digital converter employing passive resonating circuits.

    Science.gov (United States)

    Ripamonti, Giancarlo; Abba, Andrea; Geraci, Angelo

    2010-05-01

    A method for measuring time intervals accurate to the picosecond range is based on phase measurements of oscillating waveforms synchronous with their beginning and/or end. The oscillation is generated by triggering an LC resonant circuit, whose capacitance is precharged. By using high Q resonators and a final active quenching of the oscillation, it is possible to conjugate high time resolution and a small measurement time, which allows a high measurement rate. Methods for fast analysis of the data are considered and discussed with reference to computing resource requirements, speed, and accuracy. Experimental tests show the feasibility of the method and a time accuracy better than 4 ps rms. Methods aimed at further reducing hardware resources are finally discussed.

  8. High frequency, high time resolution time-to-digital converter employing passive resonating circuits

    International Nuclear Information System (INIS)

    Ripamonti, Giancarlo; Abba, Andrea; Geraci, Angelo

    2010-01-01

    A method for measuring time intervals accurate to the picosecond range is based on phase measurements of oscillating waveforms synchronous with their beginning and/or end. The oscillation is generated by triggering an LC resonant circuit, whose capacitance is precharged. By using high Q resonators and a final active quenching of the oscillation, it is possible to conjugate high time resolution and a small measurement time, which allows a high measurement rate. Methods for fast analysis of the data are considered and discussed with reference to computing resource requirements, speed, and accuracy. Experimental tests show the feasibility of the method and a time accuracy better than 4 ps rms. Methods aimed at further reducing hardware resources are finally discussed.

  9. Partial Finite-Time Synchronization of Switched Stochastic Chua's Circuits via Sliding-Mode Control

    Directory of Open Access Journals (Sweden)

    Zhang-Lin Wan

    2011-01-01

    Full Text Available This paper considers the problem of partial finite-time synchronization between switched stochastic Chua's circuits accompanied by a time-driven switching law. Based on the Ito formula and Lyapunov stability theory, a sliding-mode controller is developed to guarantee the synchronization of switched stochastic master-slave Chua's circuits and for the mean of error states to obtain the partial finite-time stability. Numerical simulations demonstrate the effectiveness of the proposed methods.

  10. Simple multifunction discriminator for multichannel triggers

    International Nuclear Information System (INIS)

    Maier, M.R.

    1982-10-01

    A simple version of a multifunction timing discriminator using only two integrated circuits is presented. It can be configured as a leading edge, a constant fraction, a zero cross or a dual threshold timing discriminator. Since so few parts are used, it is well suited for building multichannel timing discriminators. Two versions of this circuit are described: a quadruple multifunction discriminator and an octal constant fraction trigger. The different compromises made in these units are discussed. Results for walk and jitter obtained with these are presented and possible improvements are disussed

  11. The design of a semi-custom intergrated circuit for the SLAC SLC timing control system

    International Nuclear Information System (INIS)

    Linstadt, E.

    1985-01-01

    A semi-custom (gate array) integrated circuit has been designed for use in the SLAC Linear Collider timing and control system. The design process and SLAC's experiences during the phases of the design cycle are described. Issues concerning the partitioning of the design into semi-custom and standard components are discussed. Functional descriptions of the semi-custom integrated circuit and the timing module in which it is used are given

  12. Design of a semi-custom integrated circuit for the SLAC SLC timing control system

    International Nuclear Information System (INIS)

    Linstadt, E.

    1984-10-01

    A semi-custom (gate array) integrated circuit has been designed for use in the SLAC Linear Collider timing and control system. The design process and SLAC's experiences during the phases of the design cycle are described. Issues concerning the partitioning of the design into semi-custom and standard components are discussed. Functional descriptions of the semi-custom integrated circuit and the timing module in which it is used are given

  13. Low-power operation using self-timed circuits and adaptive scaling of the supply voltage

    DEFF Research Database (Denmark)

    Nielsen, Lars Skovby; Niessen, C.; Sparsø, Jens

    1994-01-01

    Recent research has demonstrated that for certain types of applications like sampled audio systems, self-timed circuits can achieve very low power consumption, because unused circuit parts automatically turn into a stand-by mode. Additional savings may be obtained by combining the self......-timed circuits with a mechanism that adaptively adjusts the supply voltage to the smallest possible, while maintaining the performance requirements. This paper describes such a mechanism, analyzes the possible power savings, and presents a demonstrator chip that has been fabricated and tested. The idea...... of voltage scaling has been used previously in synchronous circuits, and the contributions of the present paper are: 1) the combination of supply scaling and self-timed circuitry which has some unique advantages, and 2) the thorough analysis of the power savings that are possible using this technique.>...

  14. Generic top-down discrimination for sorting and partitioning in linear time

    DEFF Research Database (Denmark)

    Henglein, Fritz

    2012-01-01

    orders for rst-order recursive types, the discriminators execute in worst-case linear time. The generic discriminators can be coded compactly using list comprehensions, with order expressions specied using Generalized Algebraic Data Types (GADTs). We give some examples of the uses of discriminators....... The basic multiset discriminator for references, originally due to Paige et al., is shown to be both ecient and fully abstract: it nds all duplicates of all references occurring in a list in linear time without leaking information about their representation. In particular, it behaves deterministically...

  15. Oscillator circuits

    CERN Document Server

    Graf, Rudolf F

    1996-01-01

    This series of circuits provides designers with a quick source for oscillator circuits. Why waste time paging through huge encyclopedias when you can choose the topic you need and select any of the specialized circuits sorted by application?This book in the series has 250-300 practical, ready-to-use circuit designs, with schematics and brief explanations of circuit operation. The original source for each circuit is listed in an appendix, making it easy to obtain additional information.Ready-to-use circuits.Grouped by application for easy look-up.Circuit source listing

  16. Measuring circuits

    CERN Document Server

    Graf, Rudolf F

    1996-01-01

    This series of circuits provides designers with a quick source for measuring circuits. Why waste time paging through huge encyclopedias when you can choose the topic you need and select any of the specialized circuits sorted by application?This book in the series has 250-300 practical, ready-to-use circuit designs, with schematics and brief explanations of circuit operation. The original source for each circuit is listed in an appendix, making it easy to obtain additional information.Ready-to-use circuits.Grouped by application for easy look-up.Circuit source listings

  17. Neutron-gamma discrimination employing pattern recognition of the signal from liquid scintillator

    International Nuclear Information System (INIS)

    Kamada, Kohji; Enokido, Uhji; Ogawa, Seiji

    1999-01-01

    A pattern recognition method was applied to the neutron-gamma discrimination of the pulses from the liquid scintillator, NE-213. The circuit for the discrimination is composed of A/D converter, fast SCA, memory control circuit, two digital delay lines and two buffer memories. All components are packed on a small circuit board and are installed into a personal computer. Experiments using a weak 252 Cf n-γ source were undertaken to test the feasibility of the circuit. The circuit is of very easy adjustment and, at the same time, of very economical price when compared with usual discrimination circuits, such as the TAC system

  18. Neutron-gamma discrimination employing pattern recognition of the signal from liquid scintillator

    CERN Document Server

    Kamada, K; Ogawa, S

    1999-01-01

    A pattern recognition method was applied to the neutron-gamma discrimination of the pulses from the liquid scintillator, NE-213. The circuit for the discrimination is composed of A/D converter, fast SCA, memory control circuit, two digital delay lines and two buffer memories. All components are packed on a small circuit board and are installed into a personal computer. Experiments using a weak sup 2 sup 5 sup 2 Cf n-gamma source were undertaken to test the feasibility of the circuit. The circuit is of very easy adjustment and, at the same time, of very economical price when compared with usual discrimination circuits, such as the TAC system.

  19. Reaction times and face discrimination with emotional content

    Directory of Open Access Journals (Sweden)

    ANA MARÍA MARTÍNEZ

    2002-07-01

    Full Text Available Sixty-two university subjects students located in two groups, with a stocking of age of 21.6 for thegroup of women and 22 for the group of men with the purpose to carry out a study upon visual timesof reaction TRV with emotional content keeping in mind the position: start, half and end; the emotionalcontent: neutral, friendly and threatening; and the combinations of the stimuli. The group of womenI present TR more prolonged than that of the men in all the experimental conditions. Also it wasobserved, that more are prolonged when the stimulus to discriminate this located in the half so muchin men as women.

  20. Optical timing receiver for the NASA laser ranging system. Part I. Constant-fraction discriminator

    International Nuclear Information System (INIS)

    Leskovar, B.; Lo, C.C.

    1975-01-01

    Position-resolution capabilities of the NASA laser ranging system are essentially determined by time-resolution capabilities of its optical timing receiver. The optical timing receiver consists of a fast photoelectric device, primarily a standard of microchannel-plate-type photomultiplier or an avalanche photodiode detector, a timing discriminator, a high-precision time-interval digitizer, and a signal-processing system. The time-resolution capabilities of the receiver are determined by the photoelectron time spread of the photoelectric device, the time walk and resolution characteristics of the timing discriminator, and the time-interval digitizer. It is thus necessary to evaluate available fast photoelectronic devices with respect to their time-resolution capabilities, and to design a very low time walk timing discriminator and a high-precision time digitizer which will be used in the laser ranging system receiver. (auth)

  1. Developmental checkpoints and feedback circuits time insect maturation

    DEFF Research Database (Denmark)

    Rewitz, Kim Furbo; Yamanaka, Naoki; O'Connor, Michael B.

    2013-01-01

    as external cues, to time production and release of ecdysone. Based on results discussed here, we suggest that developmental progression to adulthood is controlled by checkpoints that regulate the genetic timing program enabling it to adapt to different environmental conditions. These checkpoints utilize...... a number of signaling pathways to modulate ecdysone production in the prothoracic gland. Release of ecdysone activates an autonomous cascade of both feedforward and feedback signals that determine the duration of the ecdysone pulse at each developmental transitions. Conservation of the genetic mechanisms...... that coordinate the juvenile-adult transition suggests that insights from the fruit fly Drosophila will provide a framework for future investigation of developmental timing in metazoans....

  2. Quantum circuit dynamics via path integrals: Is there a classical action for discrete-time paths?

    International Nuclear Information System (INIS)

    Penney, Mark D; Koh, Dax Enshan; Spekkens, Robert W

    2017-01-01

    It is straightforward to compute the transition amplitudes of a quantum circuit using the sum-over-paths methodology when the gates in the circuit are balanced, where a balanced gate is one for which all non-zero transition amplitudes are of equal magnitude. Here we consider the question of whether, for such circuits, the relative phases of different discrete-time paths through the configuration space can be defined in terms of a classical action, as they are for continuous-time paths. We show how to do so for certain kinds of quantum circuits, namely, Clifford circuits where the elementary systems are continuous-variable systems or discrete systems of odd-prime dimension. These types of circuit are distinguished by having phase-space representations that serve to define their classical counterparts. For discrete systems, the phase-space coordinates are also discrete variables. We show that for each gate in the generating set, one can associate a symplectomorphism on the phase-space and to each of these one can associate a generating function, defined on two copies of the configuration space. For discrete systems, the latter association is achieved using tools from algebraic geometry. Finally, we show that if the action functional for a discrete-time path through a sequence of gates is defined using the sum of the corresponding generating functions, then it yields the correct relative phases for the path-sum expression. These results are likely to be relevant for quantizing physical theories where time is fundamentally discrete, characterizing the classical limit of discrete-time quantum dynamics, and proving complexity results for quantum circuits. (paper)

  3. Quantum circuit dynamics via path integrals: Is there a classical action for discrete-time paths?

    Science.gov (United States)

    Penney, Mark D.; Enshan Koh, Dax; Spekkens, Robert W.

    2017-07-01

    It is straightforward to compute the transition amplitudes of a quantum circuit using the sum-over-paths methodology when the gates in the circuit are balanced, where a balanced gate is one for which all non-zero transition amplitudes are of equal magnitude. Here we consider the question of whether, for such circuits, the relative phases of different discrete-time paths through the configuration space can be defined in terms of a classical action, as they are for continuous-time paths. We show how to do so for certain kinds of quantum circuits, namely, Clifford circuits where the elementary systems are continuous-variable systems or discrete systems of odd-prime dimension. These types of circuit are distinguished by having phase-space representations that serve to define their classical counterparts. For discrete systems, the phase-space coordinates are also discrete variables. We show that for each gate in the generating set, one can associate a symplectomorphism on the phase-space and to each of these one can associate a generating function, defined on two copies of the configuration space. For discrete systems, the latter association is achieved using tools from algebraic geometry. Finally, we show that if the action functional for a discrete-time path through a sequence of gates is defined using the sum of the corresponding generating functions, then it yields the correct relative phases for the path-sum expression. These results are likely to be relevant for quantizing physical theories where time is fundamentally discrete, characterizing the classical limit of discrete-time quantum dynamics, and proving complexity results for quantum circuits.

  4. Dedicated clock/timing-circuit theories of time perception and timed performance

    NARCIS (Netherlands)

    van Rijn, Hedderik; Gu, Bon-Mi; Meck, Warren H

    2014-01-01

    Scalar Timing Theory (an information-processing version of Scalar Expectancy Theory) and its evolution into the neurobiologically plausible Striatal Beat-Frequency (SBF) theory of interval timing are reviewed. These pacemaker/accumulator or oscillation/coincidence detection models are then

  5. Dedicated clock/timing-circuit theories of time perception and timed performance.

    Science.gov (United States)

    van Rijn, Hedderik; Gu, Bon-Mi; Meck, Warren H

    2014-01-01

    Scalar Timing Theory (an information-processing version of Scalar Expectancy Theory) and its evolution into the neurobiologically plausible Striatal Beat-Frequency (SBF) theory of interval timing are reviewed. These pacemaker/accumulator or oscillation/coincidence detection models are then integrated with the Adaptive Control of Thought-Rational (ACT-R) cognitive architecture as dedicated timing modules that are able to make use of the memory and decision-making mechanisms contained in ACT-R. The different predictions made by the incorporation of these timing modules into ACT-R are discussed as well as the potential limitations. Novel implementations of the original SBF model that allow it to be incorporated into ACT-R in a more fundamental fashion than the earlier simulations of Scalar Timing Theory are also considered in conjunction with the proposed properties and neural correlates of the "internal clock".

  6. Design improvement of FPGA and CPU based digital circuit cards to solve timing issues

    International Nuclear Information System (INIS)

    Lee, Dongil; Lee, Jaeki; Lee, Kwang-Hyun

    2016-01-01

    The digital circuit cards installed at NPPs (Nuclear Power Plant) are mostly composed of a CPU (Central Processing Unit) and a PLD (Programmable Logic Device; these include a FPGA (Field Programmable Gate Array) and a CPLD (Complex Programmable Logic Device)). This type of structure is typical and is maintained using digital circuit cards. There are no big problems with this device as a structure. In particular, signal delay causes a lot of problems when various IC (Integrated Circuit) and several circuit cards are connected to the BUS of the backplane in the BUS design. This paper suggests a structure to improve the BUS signal timing problems in a circuit card consisting of CPU and FPGA. Nowadays, as the structure of circuit cards has become complex and mass data at high speed is communicated through the BUS, data integrity is the most important issue. The conventional design does not consider delay and the synchronicity of signal and this causes many problems in data processing. In order to solve these problems, it is important to isolate the BUS controller from the CPU and maintain constancy of the signal delay by using a PLD

  7. Design improvement of FPGA and CPU based digital circuit cards to solve timing issues

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Dongil; Lee, Jaeki; Lee, Kwang-Hyun [KHNP CRI, Daejeon (Korea, Republic of)

    2016-10-15

    The digital circuit cards installed at NPPs (Nuclear Power Plant) are mostly composed of a CPU (Central Processing Unit) and a PLD (Programmable Logic Device; these include a FPGA (Field Programmable Gate Array) and a CPLD (Complex Programmable Logic Device)). This type of structure is typical and is maintained using digital circuit cards. There are no big problems with this device as a structure. In particular, signal delay causes a lot of problems when various IC (Integrated Circuit) and several circuit cards are connected to the BUS of the backplane in the BUS design. This paper suggests a structure to improve the BUS signal timing problems in a circuit card consisting of CPU and FPGA. Nowadays, as the structure of circuit cards has become complex and mass data at high speed is communicated through the BUS, data integrity is the most important issue. The conventional design does not consider delay and the synchronicity of signal and this causes many problems in data processing. In order to solve these problems, it is important to isolate the BUS controller from the CPU and maintain constancy of the signal delay by using a PLD.

  8. Design and implementation of double oscillator time-to-digital converter using SFQ logic circuits

    International Nuclear Information System (INIS)

    Nishigai, T.; Ito, M.; Yoshikawa, N.; Fujimaki, A.; Terai, H.; Yorozu, S.

    2005-01-01

    We have designed, fabricated and tested a time-to-digital converter (TDC) using SFQ logic circuits. The proposed TDC consists of two sets of ring oscillators and binary counters, and a coincidence detector (CD), which detects the coincidence of the arrival of two SFQ pulses from two ring oscillators. The advantage of the proposed TDC is its simple circuit structure with wide measurement range. The time resolution of the proposed TDC is limited by the resolution of the CD, which is about 10 ps because it is made by an NDRO cell in this study. The circuits are implemented using NEC 2.5 kA/cm 2 Nb standard process and the CONNECT cell library. We have demonstrated the measurement of the propagation delay of a Josephson transmission line by the TDC with the time resolution of about 10 ps

  9. Simple circuit for precise measurement of live dead or clock time in gamma-ray spectrometry

    International Nuclear Information System (INIS)

    Hammer, W.; Sterlinski, S.

    1976-01-01

    The basic design features and characteristics of circuit are described in the paper. The circuit coupled to a multichannel analyser (MCA) enables one of times: live(Tsub(iota)), dead (Tsub(d)) or clock(Tsub(c)) to be measured precisely. Second one is measured by a built-in timer of MCA. Having the Tsub(c)/Tsub(iota) ratio and utilizing suitable mathematical formulas one can make the corrections for both main effects (dead-time and pile-up) which yield counting losses in gamma-ray spectrometry at high and/or variable activities. Two examples of the dead-time and pile-up corrections by using the new circuit are presented in this paper. (author)

  10. A new real time infrared background discrimination radiometer (BDR)

    International Nuclear Information System (INIS)

    Kopolovich, Z.; Cabib, D.; Buckwald, R.A.

    1989-01-01

    This paper reports on a new radiometer (BDR) that has been developed, which discriminates small differences between an object and its surrounding background, and is able to measure an object's changing contrast when the contrast of a moving object is to be measured against a changing background. The difference in radiant emittance of a small object against its background or of two objects with respect to each other and this difference is small compared to the emittance itself. Practical examples of such measurements are contrast measurements of airplanes and missiles in flight, contrast measurements of small, weak objects on a warm background and uniformity measurements of radiant emittance from an object's surface. Previous instruments were unable to make such measurements since the process of contrast measurement with a fixed field of view radiometer is too slow for implementation on flying objects; detection of a small difference between two large DC signals is impossible in a traditional fixed field of view radiometer when the instrument itself is saturated

  11. Peak reading detector circuit

    International Nuclear Information System (INIS)

    Courtin, E.; Grund, K.; Traub, S.; Zeeb, H.

    1975-01-01

    The peak reading detector circuit serves for picking up the instants during which peaks of a given polarity occur in sequences of signals in which the extreme values, their time intervals, and the curve shape of the signals vary. The signal sequences appear in measuring the foetal heart beat frequence from amplitude-modulated ultrasonic, electrocardiagram, and blood pressure signals. In order to prevent undesired emission of output signals from, e. g., disturbing intermediate extreme values, the circuit consists of the series connections of a circuit to simulate an ideal diode, a strong unit, a discriminator for the direction of charging current, a time-delay circuit, and an electronic switch lying in the decharging circuit of the storage unit. The time-delay circuit thereby causes storing of a preliminary maximum value being used only after a certain time delay for the emission of the output signal. If a larger extreme value occurs during the delay time the preliminary maximum value is cleared and the delay time starts running anew. (DG/PB) [de

  12. Optimization of Modulator and Circuits for Low Power Continuous-Time Delta-Sigma ADC

    DEFF Research Database (Denmark)

    Marker-Villumsen, Niels; Bruun, Erik

    2014-01-01

    This paper presents a new optimization method for achieving a minimum current consumption in a continuous-time Delta-Sigma analog-to-digital converter (ADC). The method is applied to a continuous-time modulator realised with active-RC integrators and with a folded-cascode operational transconduc...... levels are swept. Based on the results of the circuit analysis, for each modulator combination the summed current consumption of the 1st integrator and quantizer of the ADC is determined. By also sweeping the partitioning of the noise power for the different circuit parts, the optimum modulator...

  13. Wavelet transform and real-time learning method for myoelectric signal in motion discrimination

    International Nuclear Information System (INIS)

    Liu Haihua; Chen Xinhao; Chen Yaguang

    2005-01-01

    This paper discusses the applicability of the Wavelet transform for analyzing an EMG signal and discriminating motion classes. In many previous works, researchers have dealt with steady EMG and have proposed suitable analyzing methods for the EMG, for example FFT and STFT. Therefore, it is difficult for the previous approaches to discriminate motions from the EMG in the different phases of muscle activity, i.e., pre-activity, in activity, postactivity phases, as well as the period of motion transition from one to another. In this paper, we introduce the Wavelet transform using the Coiflet mother wavelet into our real-time EMG prosthetic hand controller for discriminating motions from steady and unsteady EMG. A preliminary experiment to discriminate three hand motions from four channel EMG in the initial pre-activity and in activity phase is carried out to show the effectiveness of the approach. However, future research efforts are necessary to discriminate more motions much precisely

  14. Real-time detection and discrimination of visual perception using electrocorticographic signals

    Science.gov (United States)

    Kapeller, C.; Ogawa, H.; Schalk, G.; Kunii, N.; Coon, W. G.; Scharinger, J.; Guger, C.; Kamada, K.

    2018-06-01

    Objective. Several neuroimaging studies have demonstrated that the ventral temporal cortex contains specialized regions that process visual stimuli. This study investigated the spatial and temporal dynamics of electrocorticographic (ECoG) responses to different types and colors of visual stimulation that were presented to four human participants, and demonstrated a real-time decoder that detects and discriminates responses to untrained natural images. Approach. ECoG signals from the participants were recorded while they were shown colored and greyscale versions of seven types of visual stimuli (images of faces, objects, bodies, line drawings, digits, and kanji and hiragana characters), resulting in 14 classes for discrimination (experiment I). Additionally, a real-time system asynchronously classified ECoG responses to faces, kanji and black screens presented via a monitor (experiment II), or to natural scenes (i.e. the face of an experimenter, natural images of faces and kanji, and a mirror) (experiment III). Outcome measures in all experiments included the discrimination performance across types based on broadband γ activity. Main results. Experiment I demonstrated an offline classification accuracy of 72.9% when discriminating among the seven types (without color separation). Further discrimination of grey versus colored images reached an accuracy of 67.1%. Discriminating all colors and types (14 classes) yielded an accuracy of 52.1%. In experiment II and III, the real-time decoder correctly detected 73.7% responses to face, kanji and black computer stimuli and 74.8% responses to presented natural scenes. Significance. Seven different types and their color information (either grey or color) could be detected and discriminated using broadband γ activity. Discrimination performance maximized for combined spatial-temporal information. The discrimination of stimulus color information provided the first ECoG-based evidence for color-related population

  15. Development of a coincidence circuit with nanosecond resolving time for NaI(Tl) scintillator pulses

    International Nuclear Information System (INIS)

    Ripon, R.; Coussot, G.

    1969-01-01

    The principle and the details of a slow-fast type coincidence circuit for pulses delivered by Nal(Tl) scintillators are presented. Thanks to a voluntary limitation of the analysis band (150 keV to 1 MeV) an excellent stability is obtained with respect to thermal drifts. The resolving time which has been adopted, 4 ns with 100 per cent efficiency, is quite sufficient for the projected experiment but does not represent the optimum performance of which the circuit is capable [fr

  16. A new time-digital convert circuit based on digital delay line

    International Nuclear Information System (INIS)

    Liu Haifeng; Guo Ying; Zhang Zhi

    2004-01-01

    An introduction of a new method of time-digital convert circuit based on digital delay line is given. High precision and good reliability can be realized when it is combined with traditional counting convert method in the measurement of large scale pulse width and low frequency self-excitation oscillator. (authors)

  17. Minimum-Energy Sub-Threshold Self-Timed Circuits: Design Methodology and a Case Study

    DEFF Research Database (Denmark)

    Akgun, Omer Can; Rodrigues, Joachim; Sparsø, Jens

    2010-01-01

    , which integrates the current sensing circuitry. The paper outlines a corresponding design flow, which is based on contemporary synchronous EDA tools, and which transforms a synchronous design, into a corresponding self-timed circuit. The design flow and the current-sensing technique is validated...

  18. Optimizing the switching time for 400 kV SF6 circuit breakers

    Science.gov (United States)

    Ciulica, D.

    2018-01-01

    This paper presents real-time voltage and current analysis for optimizing the wave switching point of the circuit breaker SF6. Circuit Breaker plays an important role in power systems. It provides protection for equipment in embedded stations in transport networks. SF6 Circuit Breaker is very important equipment in Power Systems, which is used for up to 400 kV due to its excellent performance. The controlled switching is used to eliminate transient modes and electrodynamic and dielectric charges in the network at manual switching of capacitor, shunt reactors and power transformers. These effects reduce the reliability and lifetime of the equipment installed on the network, or may lead to erroneous protection.

  19. CALCULATION OF CONTROL CIRCUITS IN TIME DOMAIN USING SCILAB / XCOS ENVIRONMENT

    Directory of Open Access Journals (Sweden)

    Chioncel Petru

    2014-10-01

    Full Text Available The paper presents the computing of control circuits in time domain, starting from the mathematical model of the control path described by differential equation’s with constant coefficients, whose solution can be obtained through Laplace transform and transfer functions. In the field of electric drives, the control circuits can be reduced to elements of PT1 and PT2 type, for which, the responses obtained from step and impulse function in the test process, are analyzed. The presented calculation, done in Scilab, highlights the test responses of the process and, the speed control circuit implemented as block diagrams in Xcos, reveals the improve of the process parameter through the control loop.

  20. Acquisition and processing method for human sensorial, sensitive, motory and phonatory circuits reaction times

    International Nuclear Information System (INIS)

    Doche, Claude

    1972-01-01

    This work describes a storage and acquisition device and a method for human sensorial and sensitive motory and phonatory reaction times. The considered circuits are those made with the visual, auditory and sensory receptor organs and the motory or phonatory effector organs. The anatomo-physiological localization of these circuits allows us to appreciate the possibilities of the central nervous system for different angles. The experimental population is made of normal and pathological individuals (individuals having tumoral or vascular, localized or diffused cerebral lesions or parkinsonian individuals). The parameter processing method is based on the multivariate analysis results and allows us to position each individual compared to a normal individual and to appreciate the weight of each circuit in this positioning. Clinical exploitation results give to this method a prognosis and therapeutic interest. It seems though untimely to talk about its diagnosis value. (author) [fr

  1. Real Time In-circuit Condition Monitoring of MOSFET in Power Converters

    Directory of Open Access Journals (Sweden)

    Shakeb A. Khan

    2015-03-01

    Full Text Available Abstract:This paper presents simple and low-cost, real time in-circuit condition monitoring of MOSFET in power electronic converters. Design metrics requirements like low cost, small size, high power factor, low percentage of total harmonic distortion etc. requires the power electronic systems to operate at high frequencies and at high power density. Failures of power converters are attributed largely by aging of power MOSFETs at high switching frequencies. Therefore, real time in-circuit prognostic of MOSFET needs to be done before their selection for power system design. Accelerated aging tests are performed in different circuits to determine the wear out failure of critical components based on their parametric degradation. In this paper, the simple and low-cost test beds are designed for real time in-circuit prognostics of power MOSFETs. The proposed condition monitoring scheme helps in estimating the condition of MOSFETs at their maximum rated operating condition and will aid the system designers to test their reliability and benchmark them before selecting in power converters.

  2. A quadri-constant fraction discriminator

    International Nuclear Information System (INIS)

    Wang Wei; Gu Zhongdao

    1992-01-01

    A quad Constant Fraction (Amplitude and Rise Time Compensation) Discriminator Circuit is described, which is based on the ECL high-speed dual comparator AD 9687. The CFD (ARCD) is of the constant fraction timing type (the amplitude and rise time compensation timing type) employing a leading edge discriminator to eliminate error triggers caused by noises. A timing walk measurement indicates a timing walk of less than +- 150 ps from -50 mV to -5 V

  3. Statistical analysis of error rate of large-scale single flux quantum logic circuit by considering fluctuation of timing parameters

    International Nuclear Information System (INIS)

    Yamanashi, Yuki; Masubuchi, Kota; Yoshikawa, Nobuyuki

    2016-01-01

    The relationship between the timing margin and the error rate of the large-scale single flux quantum logic circuits is quantitatively investigated to establish a timing design guideline. We observed that the fluctuation in the set-up/hold time of single flux quantum logic gates caused by thermal noises is the most probable origin of the logical error of the large-scale single flux quantum circuit. The appropriate timing margin for stable operation of the large-scale logic circuit is discussed by taking the fluctuation of setup/hold time and the timing jitter in the single flux quantum circuits. As a case study, the dependence of the error rate of the 1-million-bit single flux quantum shift register on the timing margin is statistically analyzed. The result indicates that adjustment of timing margin and the bias voltage is important for stable operation of a large-scale SFQ logic circuit.

  4. Statistical analysis of error rate of large-scale single flux quantum logic circuit by considering fluctuation of timing parameters

    Energy Technology Data Exchange (ETDEWEB)

    Yamanashi, Yuki, E-mail: yamanasi@ynu.ac.jp [Department of Electrical and Computer Engineering, Yokohama National University, Tokiwadai 79-5, Hodogaya-ku, Yokohama 240-8501 (Japan); Masubuchi, Kota; Yoshikawa, Nobuyuki [Department of Electrical and Computer Engineering, Yokohama National University, Tokiwadai 79-5, Hodogaya-ku, Yokohama 240-8501 (Japan)

    2016-11-15

    The relationship between the timing margin and the error rate of the large-scale single flux quantum logic circuits is quantitatively investigated to establish a timing design guideline. We observed that the fluctuation in the set-up/hold time of single flux quantum logic gates caused by thermal noises is the most probable origin of the logical error of the large-scale single flux quantum circuit. The appropriate timing margin for stable operation of the large-scale logic circuit is discussed by taking the fluctuation of setup/hold time and the timing jitter in the single flux quantum circuits. As a case study, the dependence of the error rate of the 1-million-bit single flux quantum shift register on the timing margin is statistically analyzed. The result indicates that adjustment of timing margin and the bias voltage is important for stable operation of a large-scale SFQ logic circuit.

  5. CAMAC differential pulse discriminator-counter

    International Nuclear Information System (INIS)

    Tselikov, N.V.

    1987-01-01

    Differential pulse discriminator-counter for Moessbauer spectrometer is described. Input pulse setting into the channel is performed according to the following algorithm: the pulse is transmitted to the channel depending on the fact whether the preceding pulse has got to the discrimination window or not. The circuit does not contain delay lines, taking into account the delay of a signal from the upper level discriminator in relation to the lower level discriminator signal, which is connected with input pulse rise finite time, which in turn allows one to reduce the discriminator dead time up to the operation time of threshold circuits. The pulse counting rate is 150 MHz, input signal amplitude is ±3 V, dead time is 6 ns, delay time from input to output is 14 ns. The unit is made in CAMAC system

  6. Fault Diagnosis for Compensating Capacitors of Jointless Track Circuit Based on Dynamic Time Warping

    Directory of Open Access Journals (Sweden)

    Wei Dong

    2014-01-01

    Full Text Available Aiming at the problem of online fault diagnosis for compensating capacitors of jointless track circuit, a dynamic time warping (DTW based diagnosis method is proposed in this paper. Different from the existing related works, this method only uses the ground indoor monitoring signals of track circuit to locate the faulty compensating capacitor, not depending on the shunt current of inspection train, which is an indispensable condition for existing methods. So, it can be used for online diagnosis of compensating capacitor, which has not yet been realized by existing methods. To overcome the key problem that track circuit cannot obtain the precise position of the train, the DTW method is used for the first time in this situation to recover the function relationship between receiver’s peak voltage and shunt position. The necessity, thinking, and procedure of the method are described in detail. Besides the classical DTW based method, two improved methods for improving classification quality and reducing computation complexity are proposed. Finally, the diagnosis experiments based on the simulation model of track circuit show the effectiveness of the proposed methods.

  7. Proposal for a fast, zero suppressing circuit for the digitization of analog pulses over long memory times

    International Nuclear Information System (INIS)

    Bourgeois, F.

    1984-01-01

    This report describes the design principles of a fast (100 MHz) time and pulse height digitizer that can record up to 15 analog pulses over 10-80 μs memory times. Unlike other triggered circuits prepulse samples are recorded without the help of an analog delay line. The low power requirements of the circuit as well as its fast read-out characteristics make it very attractive for detectors with many digitizing channels. Conventional circuits are described as a reference for the evaluation of this new design. An ECL 10 K implementation of the circuit is presented in the third section. (orig.)

  8. Discrimination of Temperature and Strain in Brillouin Optical Time Domain Analysis Using a Multicore Optical Fiber.

    Science.gov (United States)

    Zaghloul, Mohamed A S; Wang, Mohan; Milione, Giovanni; Li, Ming-Jun; Li, Shenping; Huang, Yue-Kai; Wang, Ting; Chen, Kevin P

    2018-04-12

    Brillouin optical time domain analysis is the sensing of temperature and strain changes along an optical fiber by measuring the frequency shift changes of Brillouin backscattering. Because frequency shift changes are a linear combination of temperature and strain changes, their discrimination is a challenge. Here, a multicore optical fiber that has two cores is fabricated. The differences between the cores' temperature and strain coefficients are such that temperature (strain) changes can be discriminated with error amplification factors of 4.57 °C/MHz (69.11 μ ϵ /MHz), which is 2.63 (3.67) times lower than previously demonstrated. As proof of principle, using the multicore optical fiber and a commercial Brillouin optical time domain analyzer, the temperature (strain) changes of a thermally expanding metal cylinder are discriminated with an error of 0.24% (3.7%).

  9. Discrimination of Temperature and Strain in Brillouin Optical Time Domain Analysis Using a Multicore Optical Fiber

    Directory of Open Access Journals (Sweden)

    Mohamed A. S. Zaghloul

    2018-04-01

    Full Text Available Brillouin optical time domain analysis is the sensing of temperature and strain changes along an optical fiber by measuring the frequency shift changes of Brillouin backscattering. Because frequency shift changes are a linear combination of temperature and strain changes, their discrimination is a challenge. Here, a multicore optical fiber that has two cores is fabricated. The differences between the cores’ temperature and strain coefficients are such that temperature (strain changes can be discriminated with error amplification factors of 4.57 °C/MHz (69.11 μ ϵ /MHz, which is 2.63 (3.67 times lower than previously demonstrated. As proof of principle, using the multicore optical fiber and a commercial Brillouin optical time domain analyzer, the temperature (strain changes of a thermally expanding metal cylinder are discriminated with an error of 0.24% (3.7%.

  10. Preparing printed circuit boards for rapid turn-around time on a protomat plotter

    International Nuclear Information System (INIS)

    Hawtree, J.

    1998-01-01

    This document describes the use of the LPKF ProtoMat mill/drill unit circuit board Plotter, with the associated CAD/CAM software BoardMaster and CircuitCAM. At present its primarily use here at Fermilab's Particle Physics Department is for rapid-turnover of prototype PCBs double-sided and single-sided copper clad printed circuit boards (PCBs). (The plotter is also capable of producing gravure films and engraving aluminum or plastic although we have not used it for this.) It has the capability of making traces 0.004 inch wide with 0.004 inch spacings which is appropriate for high density surface mount circuits as well as other through-mounted discrete and integrated components. One of the primary benefits of the plotter is the capability to produce double-sided drilled boards from CAD files in a few hours. However to achieve this rapid turn-around time, some care must be taken in preparing the files. This document describes how to optimize the process of PCB fabrication. With proper preparation, researchers can often have a completed circuit board in a day's time instead of a week or two wait with usual procedures. It is assumed that the software and hardware are properly installed and that the machinist is acquainted with the Win95 operating system and the basics of the associated software. This paper does not describe its use with pen plotters, lasers or rubouts. The process of creating a PCB (printed circuit board) begins with the CAD (computer-aided design) software, usually PCAD or VeriBest. These files are then moved to CAM (computer-aided machining) where they are edited and converted to put them into the proper format for running on the ProtoMat plotter. The plotter then performs the actual machining of the board. This document concentrates on the LPKF programs CircuitCam BASIS and BoardMaster for the CAM software. These programs run on a Windows 95 platform to run an LPKF ProtoMat 93s plotter

  11. Meta-analysis of field experiments shows no change in racial discrimination in hiring over time.

    Science.gov (United States)

    Quillian, Lincoln; Pager, Devah; Hexel, Ole; Midtbøen, Arnfinn H

    2017-10-10

    This study investigates change over time in the level of hiring discrimination in US labor markets. We perform a meta-analysis of every available field experiment of hiring discrimination against African Americans or Latinos ( n = 28). Together, these studies represent 55,842 applications submitted for 26,326 positions. We focus on trends since 1989 ( n = 24 studies), when field experiments became more common and improved methodologically. Since 1989, whites receive on average 36% more callbacks than African Americans, and 24% more callbacks than Latinos. We observe no change in the level of hiring discrimination against African Americans over the past 25 years, although we find modest evidence of a decline in discrimination against Latinos. Accounting for applicant education, applicant gender, study method, occupational groups, and local labor market conditions does little to alter this result. Contrary to claims of declining discrimination in American society, our estimates suggest that levels of discrimination remain largely unchanged, at least at the point of hire.

  12. Time- and Space-Order Effects in Timed Discrimination of Brightness and Size of Paired Visual Stimuli

    Science.gov (United States)

    Patching, Geoffrey R.; Englund, Mats P.; Hellstrom, Ake

    2012-01-01

    Despite the importance of both response probability and response time for testing models of choice, there is a dearth of chronometric studies examining systematic asymmetries that occur over time- and space-orders in the method of paired comparisons. In this study, systematic asymmetries in discriminating the magnitude of paired visual stimuli are…

  13. Trading speed and accuracy by coding time: a coupled-circuit cortical model.

    Directory of Open Access Journals (Sweden)

    Dominic Standage

    2013-04-01

    Full Text Available Our actions take place in space and time, but despite the role of time in decision theory and the growing acknowledgement that the encoding of time is crucial to behaviour, few studies have considered the interactions between neural codes for objects in space and for elapsed time during perceptual decisions. The speed-accuracy trade-off (SAT provides a window into spatiotemporal interactions. Our hypothesis is that temporal coding determines the rate at which spatial evidence is integrated, controlling the SAT by gain modulation. Here, we propose that local cortical circuits are inherently suited to the relevant spatial and temporal coding. In simulations of an interval estimation task, we use a generic local-circuit model to encode time by 'climbing' activity, seen in cortex during tasks with a timing requirement. The model is a network of simulated pyramidal cells and inhibitory interneurons, connected by conductance synapses. A simple learning rule enables the network to quickly produce new interval estimates, which show signature characteristics of estimates by experimental subjects. Analysis of network dynamics formally characterizes this generic, local-circuit timing mechanism. In simulations of a perceptual decision task, we couple two such networks. Network function is determined only by spatial selectivity and NMDA receptor conductance strength; all other parameters are identical. To trade speed and accuracy, the timing network simply learns longer or shorter intervals, driving the rate of downstream decision processing by spatially non-selective input, an established form of gain modulation. Like the timing network's interval estimates, decision times show signature characteristics of those by experimental subjects. Overall, we propose, demonstrate and analyse a generic mechanism for timing, a generic mechanism for modulation of decision processing by temporal codes, and we make predictions for experimental verification.

  14. Energy-minimum sub-threshold self-timed circuits using current-sensing completion detection

    DEFF Research Database (Denmark)

    Akgun, O. C.; Rodrigues, J. N.; Sparsø, Jens

    2011-01-01

    This study addresses the design of self-timed energy-minimum circuits, operating in the sub-VT domain and a generic implementation template using bundled-data circuitry and current sensing completion detection (CSCD). Furthermore, a fully decoupled latch controller was developed, which integrates......V. Spice simulations indicate a gain of 52.58% in throughput because of asynchronous operation. By trading the throughput improvement, energy dissipation is reduced by 16.8% at the energy-minimum supply voltage....

  15. Multi-channel control circuit for real-time control of events in Aditya tokamak

    Energy Technology Data Exchange (ETDEWEB)

    Edappala, Praveenlal, E-mail: praveen@ipr.res.in; Shah, Minsha; Rajpal, Rachana; Tanna, R.L.; Ghosh, Joydeep; Chattopadhyay, P.K.; Jha, R.

    2016-11-15

    Highlights: • Low cost microcontroller based control circuit. • The control hardware can be programmed/configured very easily for different applications. • Microcontroller programming is done in assembly language so that precise timing can be achieved with micro seconds resolution. • Successful implementation of this circuit in noisy tokamak environment. • Efficient noise and burst elimination. • Can be integrated in to the other subsystems. • Low cost solution for implementing feedback control in small and medium size tokamaks and other experiments requiring feedback control. - Abstract: Tokamak plasma is prone to many random events having potential for causing severe damages to the machine, such as disruptions, production and elimination of high-energy runaway electrons etc. These events can be mitigated by obtaining pre-cursor signal leading to these events and then taking proper measures just before their onset to avoid their happenings, like disruptions can be mitigated by massive gas injection or putting a bias voltage on an electrode placed inside the plasma, the runaways can be mitigated by gas injection and by applying specific magnetic fields. Hence for real time control of these events, the pre-cursors should be electronically recorded and the mitigation techniques should be initiated by sending triggers to their individual operational systems. To implement these methodologies of real-time controlling of events in Aditya Tokamak, a low cost multi-channel Micro-Controller based timing circuit is designed and developed in-house. This circuit first compares the precursor signals fed into it with the pre-set values and gives a trigger output whenever the signals overshoot the pre-set values. The circuit readies itself for operation along with start of the tokamak discharge and waits up to an initial pre-determined delay and then initiates a trigger at the time of overshooting of precursor signal. The circuit is fully integrated and assembled in

  16. Pulse duration discriminator

    International Nuclear Information System (INIS)

    Kosakovskij, L.F.

    1980-01-01

    Basic circuits of a discriminator for discrimination of pulses with the duration greater than the preset one, and of a multifunctional discriminator allowing to discriminate pulses with the duration greater (tsub(p)>tsub(s)) and lesser (tsub(p) tsub(s) and with the duration tsub(p) [ru

  17. Method and apparatus for sub-hysteresis discrimination

    Science.gov (United States)

    De Geronimo, Gianluigi

    2015-12-29

    Embodiments of comparator circuits are disclosed. A comparator circuit may include a differential input circuit, an output circuit, a positive feedback circuit operably coupled between the differential input circuit and the output circuit, and a hysteresis control circuit operably coupled with the positive feedback circuit. The hysteresis control circuit includes a switching device and a transistor. The comparator circuit provides sub-hysteresis discrimination and high speed discrimination.

  18. Robust wireless power transfer using a nonlinear parity-time-symmetric circuit.

    Science.gov (United States)

    Assawaworrarit, Sid; Yu, Xiaofang; Fan, Shanhui

    2017-06-14

    Considerable progress in wireless power transfer has been made in the realm of non-radiative transfer, which employs magnetic-field coupling in the near field. A combination of circuit resonance and impedance transformation is often used to help to achieve efficient transfer of power over a predetermined distance of about the size of the resonators. The development of non-radiative wireless power transfer has paved the way towards real-world applications such as wireless powering of implantable medical devices and wireless charging of stationary electric vehicles. However, it remains a fundamental challenge to create a wireless power transfer system in which the transfer efficiency is robust against the variation of operating conditions. Here we propose theoretically and demonstrate experimentally that a parity-time-symmetric circuit incorporating a nonlinear gain saturation element provides robust wireless power transfer. Our results show that the transfer efficiency remains near unity over a distance variation of approximately one metre, without the need for any tuning. This is in contrast with conventional methods where high transfer efficiency can only be maintained by constantly tuning the frequency or the internal coupling parameters as the transfer distance or the relative orientation of the source and receiver units is varied. The use of a nonlinear parity-time-symmetric circuit should enable robust wireless power transfer to moving devices or vehicles.

  19. Robust wireless power transfer using a nonlinear parity-time-symmetric circuit

    Science.gov (United States)

    Assawaworrarit, Sid; Yu, Xiaofang; Fan, Shanhui

    2017-06-01

    Considerable progress in wireless power transfer has been made in the realm of non-radiative transfer, which employs magnetic-field coupling in the near field. A combination of circuit resonance and impedance transformation is often used to help to achieve efficient transfer of power over a predetermined distance of about the size of the resonators. The development of non-radiative wireless power transfer has paved the way towards real-world applications such as wireless powering of implantable medical devices and wireless charging of stationary electric vehicles. However, it remains a fundamental challenge to create a wireless power transfer system in which the transfer efficiency is robust against the variation of operating conditions. Here we propose theoretically and demonstrate experimentally that a parity-time-symmetric circuit incorporating a nonlinear gain saturation element provides robust wireless power transfer. Our results show that the transfer efficiency remains near unity over a distance variation of approximately one metre, without the need for any tuning. This is in contrast with conventional methods where high transfer efficiency can only be maintained by constantly tuning the frequency or the internal coupling parameters as the transfer distance or the relative orientation of the source and receiver units is varied. The use of a nonlinear parity-time-symmetric circuit should enable robust wireless power transfer to moving devices or vehicles.

  20. A VLSI Implementation of Rank-Order Searching Circuit Employing a Time-Domain Technique

    Directory of Open Access Journals (Sweden)

    Trong-Tu Bui

    2013-01-01

    Full Text Available We present a compact and low-power rank-order searching (ROS circuit that can be used for building associative memories and rank-order filters (ROFs by employing time-domain computation and floating-gate MOS techniques. The architecture inherits the accuracy and programmability of digital implementations as well as the compactness and low-power consumption of analog ones. We aim to implement identification function as the first priority objective. Filtering function would be implemented once the location identification function has been carried out. The prototype circuit was designed and fabricated in a 0.18 μm CMOS technology. It consumes only 132.3 μW for an eight-input demonstration case.

  1. Research of time-domain equivalent circuit method in solving dispersion of coupled-cavity traveling-wave tube

    International Nuclear Information System (INIS)

    Li Wenjun; China Academy of Engineering Physics, Mianyang; Xu Zhou; Li Ming; Yang Xingfan; Chen Yanan; Liu Jie; Jin Xiao; Lin Yuzheng

    2008-01-01

    In this paper, a time-domain equivalent circuit method is applied to solve dispersion of coupled-cavity travelling-wave tube (CCTWT). First, the time-domain circuit equations of CCTWT coupled-cavity chain are deduced from the equivalent circuit model. Then, the equations are solved numerically by fourth-order Runge-Kutta method and a program CTTDCP is developed using MATLAB. Last, a L-band CCTWT is calculated using CTTDCP and the cavity pass-band of this tube is computed to be 1.08-1.48 GHz, which is consistent with the experimental results and the simulation results of electromagnetic code and demonstrates the validity of the time-domain equivalent circuit method. In addition, a new design method which uses the equivalent circuit method and electromagnetic simulation together to optimize the cold cavity characteristics of CCTWT is proposed. (authors)

  2. Theta oscillation and neuronal activity in rat hippocampus areinvolved in temporal discrimination of time in seconds

    Directory of Open Access Journals (Sweden)

    Tomoaki eNakazono

    2015-06-01

    Full Text Available The discovery of time cells revealed that the rodent hippocampus has information of time.Previous studies have suggested that a role of hippocampal time cells is to integratetemporally segregated events into a sequence using working memory with time perception.However, it is unclear that hippocampal cells contribute to time perception itself becausemost previous studies employed delayed matching-to-sample tasks that did not evaluatetime perception separately from working memory processes. Here, we investigated thefunction of the rat hippocampus in time perception using a temporal discrimination task. Inthe task, rats had to discriminate between durations of 1 and 3 sec to get a reward, andmaintaining task-related information as working memory was not required. We found thatsome hippocampal neurons showed firing rate modulation similar to that of time cells.Moreover, theta oscillation of local field potentials (LFPs showed a transient enhancementof power during time discrimination periods. However, there were little relationshipsbetween the neuronal activities and theta oscillations. These results suggest that both theindividual neuronal activities and theta oscillations of LFPs in the hippocampus have a possibility to be engaged in seconds order time perception; however, they participate in different ways.

  3. Hidden discriminative features extraction for supervised high-order time series modeling.

    Science.gov (United States)

    Nguyen, Ngoc Anh Thi; Yang, Hyung-Jeong; Kim, Sunhee

    2016-11-01

    In this paper, an orthogonal Tucker-decomposition-based extraction of high-order discriminative subspaces from a tensor-based time series data structure is presented, named as Tensor Discriminative Feature Extraction (TDFE). TDFE relies on the employment of category information for the maximization of the between-class scatter and the minimization of the within-class scatter to extract optimal hidden discriminative feature subspaces that are simultaneously spanned by every modality for supervised tensor modeling. In this context, the proposed tensor-decomposition method provides the following benefits: i) reduces dimensionality while robustly mining the underlying discriminative features, ii) results in effective interpretable features that lead to an improved classification and visualization, and iii) reduces the processing time during the training stage and the filtering of the projection by solving the generalized eigenvalue issue at each alternation step. Two real third-order tensor-structures of time series datasets (an epilepsy electroencephalogram (EEG) that is modeled as channel×frequency bin×time frame and a microarray data that is modeled as gene×sample×time) were used for the evaluation of the TDFE. The experiment results corroborate the advantages of the proposed method with averages of 98.26% and 89.63% for the classification accuracies of the epilepsy dataset and the microarray dataset, respectively. These performance averages represent an improvement on those of the matrix-based algorithms and recent tensor-based, discriminant-decomposition approaches; this is especially the case considering the small number of samples that are used in practice. Copyright © 2016 Elsevier Ltd. All rights reserved.

  4. Time-space modal logic for verification of bit-slice circuits

    Science.gov (United States)

    Hiraishi, Hiromi

    1996-03-01

    The major goal of this paper is to propose a new modal logic aiming at formal verification of bit-slice circuits. The new logic is called as time-space modal logic and its major feature is that it can handle two transition relations: one for time transition and the other for space transition. As for a verification algorithm, a symbolic model checking algorithm of the new logic is shown. This could be applicable to verification of bit-slice microprocessor of infinite bit width and 1D systolic array of infinite length. A simple benchmark result shows the effectiveness of the proposed approach.

  5. Discrimination in waiting times by insurance type and financial soundness of German acute care hospitals.

    Science.gov (United States)

    Schwierz, Christoph; Wübker, Achim; Wübker, Ansgar; Kuchinke, Björn A

    2011-10-01

    This paper shows that patients with private health insurance (PHI) are being offered significantly shorter waiting times than patients with statutory health insurance (SHI) in German acute hospital care. This behavior may be driven by the higher expected profitability of PHI relative to SHI holders. Further, we find that hospitals offering private insurees shorter waiting times when compared with SHI holders have a significantly better financial performance than those abstaining from or with less discrimination.

  6. TOFPET 2: A high-performance circuit for PET time-of-flight

    Energy Technology Data Exchange (ETDEWEB)

    Di Francesco, Agostino, E-mail: agodifra@lip.pt [LIP, Lisbon (Portugal); Bugalho, Ricardo [LIP, Lisbon (Portugal); PETsys Electronics, Oeiras (Portugal); Oliveira, Luis [CTS-UNINOVA, DEE FCT-UNL, Caparica (Portugal); Rivetti, Angelo [INFN - sez. Torino (Italy); Rolo, Manuel [LIP, Lisbon (Portugal); INFN - sez. Torino (Italy); Silva, Jose C.; Varela, Joao [LIP, Lisbon (Portugal); PETsys Electronics, Oeiras (Portugal)

    2016-07-11

    We present a readout and digitization ASIC featuring low-noise and low-power for time-of flight (TOF) applications using SiPMs. The circuit is designed in standard CMOS 110 nm technology, has 64 independent channels and is optimized for time-of-flight measurement in Positron Emission Tomography (TOF-PET). The input amplifier is a low impedance current conveyor based on a regulated common-gate topology. Each channel has quad-buffered analogue interpolation TDCs (time binning 20 ps) and charge integration ADCs with linear response at full scale (1500 pC). The signal amplitude can also be derived from the measurement of time-over-threshold (ToT). Simulation results show that for a single photo-electron signal with charge 200 (550) fC generated by a SiPM with (320 pF) capacitance the circuit has 24 (30) dB SNR, 75 (39) ps r.m.s. resolution, and 4 (8) mW power consumption. The event rate is 600 kHz per channel, with up to 2 MHz dark counts rejection.

  7. Discriminating cosmic muons and X-rays based on rise time using a GEM detector

    Science.gov (United States)

    Wu, Hui-Yin; Zhao, Sheng-Ying; Wang, Xiao-Dong; Zhang, Xian-Ming; Qi, Hui-Rong; Zhang, Wei; Wu, Ke-Yan; Hu, Bi-Tao; Zhang, Yi

    2016-08-01

    Gas electron multiplier (GEM) detectors have been used in cosmic muon scattering tomography and neutron imaging over the last decade. In this work, a triple GEM device with an effective readout area of 10 cm × 10 cm is developed, and a method of discriminating between cosmic muons and X-rays based on rise time is tested. The energy resolution of the GEM detector is tested by 55Fe ray source to prove the GEM detector has a good performance. Analysis of the complete signal-cycles allows us to get the rise time and pulse heights. The experiment result indicates that cosmic muons and X-rays can be discriminated with an appropriate rise time threshold. Supported by National Natural Science Foundation of China (11135002, 11275235, 11405077, 11575073)

  8. Multiobjective Optimization for Electronic Circuit Design in Time and Frequency Domains

    Directory of Open Access Journals (Sweden)

    J. Dobes

    2013-04-01

    Full Text Available The multiobjective optimization provides an extraordinary opportunity for the finest design of electronic circuits because it allows to mathematically balance contradictory requirements together with possible constraints. In this paper, an original and substantial improvement of an existing method for the multiobjective optimization known as GAM (Goal Attainment Method is suggested. In our proposal, the GAM algorithm itself is combined with a procedure that automatically provides a set of parameters -- weights, coordinates of the reference point -- for which the method generates noninferior solutions uniformly spread over an appropriately selected part of the Pareto front. Moreover, the resulting set of obtained solutions is then presented in a suitable graphic form so that the solution representing the most satisfactory tradeoff can be easily chosen by the designer. Our system generates various types of plots that conveniently characterize results of up to four-dimensional problems. Technically, the procedures of the multiobjective optimization were created as a software add-on to the CIA (Circuit Interactive Analyzer program. This way enabled us to utilize many powerful features of this program, including the sensitivity analyses in time and frequency domains. As a result, the system is also able to perform the multiobjective optimization in the time domain and even highly nonlinear circuits can be significantly improved by our program. As a demonstration of this feature, a multiobjective optimization of a C-class power amplifier in the time domain is thoroughly described in the paper. Further, a four-dimensional optimization of a video amplifier is demonstrated with an original graphic representation of the Pareto front, and also some comparison with the weighting method is done. As an example of improving noise properties, a multiobjective optimization of a low-noise amplifier is performed, and the results in the frequency domain are shown

  9. Parametric, nonparametric and parametric modelling of a chaotic circuit time series

    Science.gov (United States)

    Timmer, J.; Rust, H.; Horbelt, W.; Voss, H. U.

    2000-09-01

    The determination of a differential equation underlying a measured time series is a frequently arising task in nonlinear time series analysis. In the validation of a proposed model one often faces the dilemma that it is hard to decide whether possible discrepancies between the time series and model output are caused by an inappropriate model or by bad estimates of parameters in a correct type of model, or both. We propose a combination of parametric modelling based on Bock's multiple shooting algorithm and nonparametric modelling based on optimal transformations as a strategy to test proposed models and if rejected suggest and test new ones. We exemplify this strategy on an experimental time series from a chaotic circuit where we obtain an extremely accurate reconstruction of the observed attractor.

  10. Estimation of optimum time interval for neutron- γ discrimination by simplified digital charge collection method

    International Nuclear Information System (INIS)

    Singh, Harleen; Singh, Sarabjeet

    2014-01-01

    The discrimination of mixed radiation field is of prime importance due to its application in neutron detection which leads to radiation safety, nuclear material detection etc. The liquid scintillators are one of the most important radiation detectors because the relative decay rate of neutron pulse is slower as compared to gamma radiation in these detectors. There are techniques like zero crossing and charge comparison which are very popular and implemented using analogue electronics. In the recent years due to availability of fast ADC and FPGA, digital methods for discrimination of mixed field radiations have been investigated. Some of the digital time domain techniques developed are pulse gradient analysis (PGA), simplified digital charge collection method (SDCC), digital zero crossing method. The performance of these methods depends on the appropriate selection of gate time for which the pulse is processed. In this paper, the SDCC method is investigated for a neutron-gamma mixed field. The main focus of the study is to get the knowledge of optimum gate time which is very important in neutron gamma discrimination analysis in a mixed radiation field. The comparison with charge collection (CC) method is also investigated

  11. Optimal testing input sets for reduced diagnosis time of nuclear power plant digital electronic circuits

    International Nuclear Information System (INIS)

    Kim, D.S.; Seong, P.H.

    1994-01-01

    This paper describes the optimal testing input sets required for the fault diagnosis of the nuclear power plant digital electronic circuits. With the complicated systems such as very large scale integration (VLSI), nuclear power plant (NPP), and aircraft, testing is the major factor of the maintenance of the system. Particularly, diagnosis time grows quickly with the complexity of the component. In this research, for reduce diagnosis time the authors derived the optimal testing sets that are the minimal testing sets required for detecting the failure and for locating of the failed component. For reduced diagnosis time, the technique presented by Hayes fits best for the approach to testing sets generation among many conventional methods. However, this method has the following disadvantages: (a) it considers only the simple network (b) it concerns only whether the system is in failed state or not and does not provide the way to locate the failed component. Therefore the authors have derived the optimal testing input sets that resolve these problems by Hayes while preserving its advantages. When they applied the optimal testing sets to the automatic fault diagnosis system (AFDS) which incorporates the advanced fault diagnosis method of artificial intelligence technique, they found that the fault diagnosis using the optimal testing sets makes testing the digital electronic circuits much faster than that using exhaustive testing input sets; when they applied them to test the Universal (UV) Card which is a nuclear power plant digital input/output solid state protection system card, they reduced the testing time up to about 100 times

  12. Time-of-flight discrimination between gamma-rays and neutrons by using artificial neural networks

    International Nuclear Information System (INIS)

    Akkoyun, S.

    2013-01-01

    Highlights: ► Time-of-flight (tof) is an obvious method for separation between gamma and neutron particles. ► tof distributions are obtained by neural networks. ► Neural network method is consistent with the experimental results. ► Neural networks can classify different events for discrimination. - Abstract: In gamma-ray spectroscopy, a number of neutrons are emitted from the nuclei together with the gamma-rays. These neutrons influence gamma-ray spectra. An obvious method for discrimination between neutrons and gamma-rays is based on the time-of-flight (tof) technique. In this work, the tof distributions of gamma-rays and neutrons were obtained both experimentally and by using artificial neural networks (ANNs). It was shown that, ANN can correctly classify gamma-ray and neutron events. Also, for highly nonlinear detector response for tof, we have constructed consistent empirical physical formulas (EPFs) by appropriate ANNs. These ANN–EPFs can be used to derive further physical functions which could be relevant to discrimination between gamma-rays and neutrons

  13. Development of high speed integrated circuit for very high resolution timing measurements

    International Nuclear Information System (INIS)

    Mester, Christian

    2009-10-01

    A multi-channel high-precision low-power time-to-digital converter application specific integrated circuit for high energy physics applications has been designed and implemented in a 130 nm CMOS process. To reach a target resolution of 24.4 ps, a novel delay element has been conceived. This nominal resolution has been experimentally verified with a prototype, with a minimum resolution of 19 ps. To further improve the resolution, a new interpolation scheme has been described. The ASIC has been designed to use a reference clock with the LHC bunch crossing frequency of 40 MHz and generate all required timing signals internally, to ease to use within the framework of an LHC upgrade. Special care has been taken to minimise the power consumption. (orig.)

  14. Development of high speed integrated circuit for very high resolution timing measurements

    Energy Technology Data Exchange (ETDEWEB)

    Mester, Christian

    2009-10-15

    A multi-channel high-precision low-power time-to-digital converter application specific integrated circuit for high energy physics applications has been designed and implemented in a 130 nm CMOS process. To reach a target resolution of 24.4 ps, a novel delay element has been conceived. This nominal resolution has been experimentally verified with a prototype, with a minimum resolution of 19 ps. To further improve the resolution, a new interpolation scheme has been described. The ASIC has been designed to use a reference clock with the LHC bunch crossing frequency of 40 MHz and generate all required timing signals internally, to ease to use within the framework of an LHC upgrade. Special care has been taken to minimise the power consumption. (orig.)

  15. MTR2: a discriminator and dead-time module used in counting systems

    International Nuclear Information System (INIS)

    Bouchard, J.

    2000-01-01

    In the field of radioactivity measurement, there is a constant need for highly specialized electronic modules such as ADCs, amplifiers, discriminators, dead-time modules, etc. But sometimes it is almost impossible to find on the market the modules having the performances corresponding to our needs. The purpose of the module presented here, called MTR2 (Module de Temps-mort Reconductible), is to process, in terms of pulse height discrimination and dead-time corrections, the pulses delivered by the detectors used in counting systems. This dead-time, of the extendible type, is triggered by both the positive and negative parts of the incoming pulse and the dead-time corrections are made according to the live-time method. This module, which has been developed and tested at LPRI, can be used alone in simple counting channels or in more complex systems such as coincidence systems. The philosophy governing the choice and the implementation of this type of dead-time as well as the system used for the dead-time corrections is presented. The electronic scheme and the performances are also presented. This module is available in the NIM standard

  16. A Recurrent Probabilistic Neural Network with Dimensionality Reduction Based on Time-series Discriminant Component Analysis.

    Science.gov (United States)

    Hayashi, Hideaki; Shibanoki, Taro; Shima, Keisuke; Kurita, Yuichi; Tsuji, Toshio

    2015-12-01

    This paper proposes a probabilistic neural network (NN) developed on the basis of time-series discriminant component analysis (TSDCA) that can be used to classify high-dimensional time-series patterns. TSDCA involves the compression of high-dimensional time series into a lower dimensional space using a set of orthogonal transformations and the calculation of posterior probabilities based on a continuous-density hidden Markov model with a Gaussian mixture model expressed in the reduced-dimensional space. The analysis can be incorporated into an NN, which is named a time-series discriminant component network (TSDCN), so that parameters of dimensionality reduction and classification can be obtained simultaneously as network coefficients according to a backpropagation through time-based learning algorithm with the Lagrange multiplier method. The TSDCN is considered to enable high-accuracy classification of high-dimensional time-series patterns and to reduce the computation time taken for network training. The validity of the TSDCN is demonstrated for high-dimensional artificial data and electroencephalogram signals in the experiments conducted during the study.

  17. Energy discrimination for positron emission tomography using the time information of the first detected photons

    Science.gov (United States)

    Therrien, A. C.; Lemaire, W.; Lecoq, P.; Fontaine, R.; Pratte, J.-F.

    2018-01-01

    The advantages of Time-of-Flight positron emission tomography (TOF-PET) have pushed the development of detectors with better time resolution. In particular, Silicon Photomultipliers (SiPM) have evolved tremendously in the past decade and arrays with a fully digital readout are the next logical step (dSiPM). New multi-timestamp methods use the precise time information of multiple photons to estimate the time of a PET event with greater accuracy, resulting in excellent time resolution. We propose a method which uses the same timestamps as the time estimator to perform energy discrimination, thus using data obtained within 5 ns of the beginning of the event. Having collected all the necessary information, the dSiPM could then be disabled for the remaining scintillation while dedicated electronics process the collected data. This would reduce afterpulsing as the SPAD would be turned off for several hundred nanoseconds, emptying the majority of traps. The proposed method uses a strategy based on subtraction and minimal electronics to reject energy below a selected threshold. This method achieves an error rate of less than 3% for photopeak discrimination (threshold at 400 keV) for dark count rates up to 100 cps/μm2, time-to-digital converter resolution up to 50 ps and a photon detection efficiency ranging from 10 to 70%.

  18. Time-of-flight positron emission tomography using optical fiber circuit

    International Nuclear Information System (INIS)

    Yamawaki, Masato; Katsumura, Yousuke; Suzuki, Takenori

    2008-01-01

    The measurement method and system architecture of a new time-of-flight positron emission tomography (TOF-PET) system are proposed. This system collects scintillation light using optical fibers connected directly to scintillators and measures the position of positron annihilation. Many scintillators are placed cylindrically whereby a pair of scintillators detects a pair of γ-rays generated at the positron annihilation point. Optical fiber circuits, most of which are bundles of optical fibers bound clockwise or counterclockwise around the cylinder of scintillators, collect light signals generated by γ-rays. These light signals are amplified by several photomultiplier tubes and processed using a single digital oscilloscope to determine the TOF of the positron annihilation γ-rays. One of the most important factors in the performance of the TOF-PET system is the TOF resolution. When fiber circuits are used for transmitting light signals, the dispersion of light signals and the decrease in light intensity are the major factors in the deterioration of the TOF resolution. The result of the preliminary experiment leads to the conclusion that the use of optical fibers degrades the intensity of light but does not severely degrade the TOF resolution. (author)

  19. Robust motion artefact resistant circuit for calculation of Mean Arterial Pressure from pulse transit time.

    Science.gov (United States)

    Bhattacharya, Tinish; Gupta, Ankesh; Singh, Salam ThoiThoi; Roy, Sitikantha; Prasad, Anamika

    2017-07-01

    Cuff-less and non-invasive methods of Blood Pressure (BP) monitoring have faced a lot of challenges like stability, noise, motion artefact and requirement for calibration. These factors are the major reasons why such devices do not get approval from the medical community easily. One such method is calculating Blood Pressure indirectly from pulse transit time (PTT) obtained from electrocardiogram (ECG) and Photoplethysmogram (PPG). In this paper we have proposed two novel analog signal conditioning circuits for ECG and PPG that increase stability, remove motion artefacts, remove the sinusoidal wavering of the ECG baseline due to respiration and provide consistent digital pulses corresponding to blood pulses/heart-beat. We have combined these two systems to obtain the PTT and then correlated it with the Mean Arterial Pressure (MAP). The aim was to perform major part of the processing in analog domain to decrease processing load over microcontroller so as to reduce cost and make it simple and robust. We have found from our experiments that the proposed circuits can calculate the Heart Rate (HR) with a maximum error of ~3.0% and MAP with a maximum error of ~2.4% at rest and ~4.6% in motion.

  20. Effecting aging time of epoxy molding compound to molding process for integrated circuit packaging

    Science.gov (United States)

    Tachapitunsuk, Jirayu; Ugsornrat, Kessararat; Srisuwitthanon, Warayoot; Thonglor, Panakamon

    2017-09-01

    This research studied about effecting aging time of epoxy molding compound (EMC) that effect to reliability performance of integrated circuit (IC) package in molding process. Molding process is so important of IC packaging process for protecting IC chip (or die) from temperature and humidity environment using encapsulated EMC. For general molding process, EMC are stored in the frozen at 5°C and left at room temperature at 25 °C for aging time on self before molding of die onto lead frame is 24 hours. The aging time effect to reliability performance of IC package due to different temperature and humidity inside the package. In experiment, aging time of EMC were varied from 0 to 24 hours for molding process of SOIC-8L packages. For analysis, these packages were tested by x-ray and scanning acoustic microscope to analyze properties of EMC with an aging time and also analyzed delamination, internal void, and wire sweep inside the packages with different aging time. The results revealed that different aging time of EMC effect to properties and reliability performance of molding process.

  1. Bioelectric signal classification using a recurrent probabilistic neural network with time-series discriminant component analysis.

    Science.gov (United States)

    Hayashi, Hideaki; Shima, Keisuke; Shibanoki, Taro; Kurita, Yuichi; Tsuji, Toshio

    2013-01-01

    This paper outlines a probabilistic neural network developed on the basis of time-series discriminant component analysis (TSDCA) that can be used to classify high-dimensional time-series patterns. TSDCA involves the compression of high-dimensional time series into a lower-dimensional space using a set of orthogonal transformations and the calculation of posterior probabilities based on a continuous-density hidden Markov model that incorporates a Gaussian mixture model expressed in the reduced-dimensional space. The analysis can be incorporated into a neural network so that parameters can be obtained appropriately as network coefficients according to backpropagation-through-time-based training algorithm. The network is considered to enable high-accuracy classification of high-dimensional time-series patterns and to reduce the computation time taken for network training. In the experiments conducted during the study, the validity of the proposed network was demonstrated for EEG signals.

  2. Fast neutron flux analyzer with real-time digital pulse shape discrimination

    Energy Technology Data Exchange (ETDEWEB)

    Ivanova, A.A., E-mail: a.a.ivanova@inp.nsk.su [Budker Institute of Nuclear Physics SB RAS, 630090 Novosibirsk (Russian Federation); Zubarev, P.V. [Budker Institute of Nuclear Physics SB RAS, 630090 Novosibirsk (Russian Federation); Novosibirsk State Technical University, 630092 Novosibirsk (Russian Federation); Ivanenko, S.V. [Budker Institute of Nuclear Physics SB RAS, 630090 Novosibirsk (Russian Federation); Khilchenko, A.D. [Budker Institute of Nuclear Physics SB RAS, 630090 Novosibirsk (Russian Federation); Novosibirsk State Technical University, 630092 Novosibirsk (Russian Federation); Kotelnikov, A.I. [Budker Institute of Nuclear Physics SB RAS, 630090 Novosibirsk (Russian Federation); Polosatkin, S.V. [Budker Institute of Nuclear Physics SB RAS, 630090 Novosibirsk (Russian Federation); Novosibirsk State Technical University, 630092 Novosibirsk (Russian Federation); Novosibirsk State University, 630090 Novosibirsk (Russian Federation); Puryga, E.A.; Shvyrev, V.G. [Budker Institute of Nuclear Physics SB RAS, 630090 Novosibirsk (Russian Federation); Novosibirsk State Technical University, 630092 Novosibirsk (Russian Federation); Sulyaev, Yu.S. [Budker Institute of Nuclear Physics SB RAS, 630090 Novosibirsk (Russian Federation); Novosibirsk State University, 630090 Novosibirsk (Russian Federation)

    2016-08-11

    Investigation of subthermonuclear plasma confinement and heating in magnetic fusion devices such as GOL–3 and GDT at the Budker Institute (Novosibirsk, Russia) requires sophisticated equipment for neutron-, gamma- diagnostics and upgrading data acquisition systems with online data processing. Measurement of fast neutron flux with stilbene scintillation detectors raised the problem of discrimination of the neutrons (n) from background cosmic particles (muons) and neutron-induced gamma rays (γ). This paper describes a fast neutron flux analyzer with real-time digital pulse-shape discrimination (DPSD) algorithm FPGA-implemented for the GOL–3 and GDT devices. This analyzer was tested and calibrated with the help of {sup 137}Cs and {sup 252}Cf radiation sources. The Figures of Merit (FOM) calculated for different energy cuts are presented. - Highlights: • Electronic equipment for measurement of fast neutron flux with stilbene scintillator is presented. • FPGA-implemented digital pulse-shape discrimination algorithm by charge comparison method is shown. • Calibration of analyzer was carried out with {sup 137}Cs and {sup 252}Cf. • Figures of Merit (FOM) values for energy cuts from 1/8 Cs to 2 Cs are from 1.264 to 2.34 respectively.

  3. Approximate number and approximate time discrimination each correlate with school math abilities in young children.

    Science.gov (United States)

    Odic, Darko; Lisboa, Juan Valle; Eisinger, Robert; Olivera, Magdalena Gonzalez; Maiche, Alejandro; Halberda, Justin

    2016-01-01

    What is the relationship between our intuitive sense of number (e.g., when estimating how many marbles are in a jar), and our intuitive sense of other quantities, including time (e.g., when estimating how long it has been since we last ate breakfast)? Recent work in cognitive, developmental, comparative psychology, and computational neuroscience has suggested that our representations of approximate number, time, and spatial extent are fundamentally linked and constitute a "generalized magnitude system". But, the shared behavioral and neural signatures between number, time, and space may alternatively be due to similar encoding and decision-making processes, rather than due to shared domain-general representations. In this study, we investigate the relationship between approximate number and time in a large sample of 6-8 year-old children in Uruguay by examining how individual differences in the precision of number and time estimation correlate with school mathematics performance. Over four testing days, each child completed an approximate number discrimination task, an approximate time discrimination task, a digit span task, and a large battery of symbolic math tests. We replicate previous reports showing that symbolic math abilities correlate with approximate number precision and extend those findings by showing that math abilities also correlate with approximate time precision. But, contrary to approximate number and time sharing common representations, we find that each of these dimensions uniquely correlates with formal math: approximate number correlates more strongly with formal math compared to time and continues to correlate with math even when precision in time and individual differences in working memory are controlled for. These results suggest that there are important differences in the mental representations of approximate number and approximate time and further clarify the relationship between quantity representations and mathematics. Copyright

  4. A 16-channel real-time digital processor for pulse-shape discrimination in multiplicity assay

    International Nuclear Information System (INIS)

    Joyce, Malcolm J.; Aspinall, M.D.; Cave, F.D.; Lavietes, A.

    2013-06-01

    In recent years, real-time neutron/γ-ray pulse-shape discrimination has become feasible for use with scintillator-based detectors that respond extremely quickly, on the order of 25 ns in terms of pulse width, and their application to a variety of nuclear material assays has been reported. For the in-situ analysis of nuclear materials, measurements are often based on the multiplicity assessment of spontaneous fission events. An example of this is the 240 Pu eff assessment stemming from long-established techniques developed for 3 He-based neutron coincidence counters when 3 He was abundant and cheap. However, such measurements when using scintillator detectors can be plagued by low detection efficiencies and low orders of coincidence (often limited to triples) if the number of detectors in use is similarly limited to 3-4 detectors. Conversely, an array of >10 detector modules arranged to optimize efficiency and multiplicity sensitivity, shifts the emphasis in terms of performance requirement to the real-time digital analyzer and, critically, to the scope remaining in the temporal processing window of these systems. In this paper we report on the design, development and commissioning of a bespoke, 16-channel real-time pulse-shape discrimination analyzer specified for the materials assay challenge summarized above. The analyzer incorporates 16 dedicated and independent high-voltage supplies along with 16 independent digital processing channels offering pulse-shape discrimination at a rate of 3 x 10 6 events per second. These functions are configured from a dedicated graphical user interface, and all settings can be adjusted on-the-fly with the analyzer effectively configured one-time-only (where desired) for subsequent plug-and-play connection, for example to a fuel bundle organic scintillation detector array. (authors)

  5. New readout integrated circuit using continuous time fixed pattern noise correction

    Science.gov (United States)

    Dupont, Bertrand; Chammings, G.; Rapellin, G.; Mandier, C.; Tchagaspanian, M.; Dupont, Benoit; Peizerat, A.; Yon, J. J.

    2008-04-01

    LETI has been involved in IRFPA development since 1978; the design department (LETI/DCIS) has focused its work on new ROIC architecture since many years. The trend is to integrate advanced functions into the CMOS design to achieve cost efficient sensors production. Thermal imaging market is today more and more demanding of systems with instant ON capability and low power consumption. The purpose of this paper is to present the latest developments of fixed pattern noise continuous time correction. Several architectures are proposed, some are based on hardwired digital processing and some are purely analog. Both are using scene based algorithms. Moreover a new method is proposed for simultaneous correction of pixel offsets and sensitivities. In this scope, a new architecture of readout integrated circuit has been implemented; this architecture is developed with 0.18μm CMOS technology. The specification and the application of the ROIC are discussed in details.

  6. England's time to change antistigma campaign: one-year outcomes of service user-rated experiences of discrimination.

    Science.gov (United States)

    Henderson, Claire; Corker, Elizabeth; Lewis-Holmes, Elanor; Hamilton, Sarah; Flach, Clare; Rose, Diana; Williams, Paul; Pinfold, Vanessa; Thornicroft, Graham

    2012-01-01

    This study evaluated the progress at one year of England's Time to Change (TTC) program, launched in 2009, toward meeting its target to reduce mental health-related stigma and discrimination by 5%. TTC comprises three national components: antistigma marketing campaign activities, mass physical exercise events (Time to Get Moving) to facilitate social contact between people with and without mental health problems, and an online resource on mental health and employment (Time to Challenge). Part of the TTC evaluation consists of an annual national phone survey of mental health service users. Participants (537 in 2008 and 1,047 in 2009) were current outpatient service users aged 18-65 registered with National Health Service community mental health teams that are selected annually to represent the range of socioeconomic deprivation. Telephone interviews were conducted with service users with the Discrimination and Stigma Scale (DISC) to document experienced discrimination and anticipated discrimination in the past 12 months. One or more experiences of discrimination were reported by 9-1% of participants in 2008 and 87% of participants in 2009 (p = .03). In 2009 significantly less discrimination was reported from a number of common sources, including family (reported by 53% in 2008 and 46% in 2009), friends (53% and 39%), finding employment (24% and 16%), and keeping employment (from 17% to 13%). Experiences of discrimination from mental health professionals did not change significantly (reported by about one-third of participants in both years). Results suggest positive progress toward meeting the program's targeted 5% reduction in discrimination.

  7. A Time-Walk Correction Method for PET Detectors Based on Leading Edge Discriminators.

    Science.gov (United States)

    Du, Junwei; Schmall, Jeffrey P; Judenhofer, Martin S; Di, Kun; Yang, Yongfeng; Cherry, Simon R

    2017-09-01

    The leading edge timing pick-off technique is the simplest timing extraction method for PET detectors. Due to the inherent time-walk of the leading edge technique, corrections should be made to improve timing resolution, especially for time-of-flight PET. Time-walk correction can be done by utilizing the relationship between the threshold crossing time and the event energy on an event by event basis. In this paper, a time-walk correction method is proposed and evaluated using timing information from two identical detectors both using leading edge discriminators. This differs from other techniques that use an external dedicated reference detector, such as a fast PMT-based detector using constant fraction techniques to pick-off timing information. In our proposed method, one detector was used as reference detector to correct the time-walk of the other detector. Time-walk in the reference detector was minimized by using events within a small energy window (508.5 - 513.5 keV). To validate this method, a coincidence detector pair was assembled using two SensL MicroFB SiPMs and two 2.5 mm × 2.5 mm × 20 mm polished LYSO crystals. Coincidence timing resolutions using different time pick-off techniques were obtained at a bias voltage of 27.5 V and a fixed temperature of 20 °C. The coincidence timing resolution without time-walk correction were 389.0 ± 12.0 ps (425 -650 keV energy window) and 670.2 ± 16.2 ps (250-750 keV energy window). The timing resolution with time-walk correction improved to 367.3 ± 0.5 ps (425 - 650 keV) and 413.7 ± 0.9 ps (250 - 750 keV). For comparison, timing resolutions were 442.8 ± 12.8 ps (425 - 650 keV) and 476.0 ± 13.0 ps (250 - 750 keV) using constant fraction techniques, and 367.3 ± 0.4 ps (425 - 650 keV) and 413.4 ± 0.9 ps (250 - 750 keV) using a reference detector based on the constant fraction technique. These results show that the proposed leading edge based time-walk correction method works well. Timing resolution obtained

  8. Time, number and length: similarities and differences in discrimination in adults and children.

    Science.gov (United States)

    Droit-Volet, Sylvie; Clément, Angélique; Fayol, Michel

    2008-01-01

    The aim of this study was to focus on similarities in the discrimination of three different quantities--time, number, and line length--using a bisection task involving children aged 5 and 8 years and adults, when number and length were presented nonsequentially (Experiment 1) and sequentially (Experiment 2). In the nonsequential condition, for all age groups, although to a greater extent in the younger children, the psychophysical functions were flatter, and the Weber ratio higher for time than for number and length. Number and length yielded similar psychophysical functions. Thus, sensitivity to time was lower than that to the other quantities, whether continuous or not. However, when number and length were presented sequentially (Experiment 2), the differences in discrimination performance between time, number, and length disappeared. Furthermore, the Weber ratio values as well as the bisection points for all quantities presented sequentially appeared to be close to that found for duration in the nonsequential condition. The results are discussed within the framework of recent theories suggesting a common mechanism for all analogical quantities.

  9. Convergent and discriminant validity of time attitude scores on the adolescent time perspective inventory

    OpenAIRE

    Worrel, Frank C.; Mello, Zena R.

    2009-01-01

    "In this study, we report on the validity of time attitude scores on the Adolescent Time Perspective Inventory-Time Attitudes (ATPI-TA; Mello/ Worrell 2007) Scales. The ATPI-TA has six subscales: Past Positive, Past Negative, Present Positive, Present Negative, Future Positive, and Future Negative. Participants consisted of 300 adolescents from rural, urban, and suburban schools and a range of socioeconomic backgrounds. All time attitude subscales were interrelated, with correlations in the a...

  10. Digital algorithms to recognize shot circuits just in right time. Digitale Algorithmen zur fruehzeitigen Kurzschlusserkennung

    Energy Technology Data Exchange (ETDEWEB)

    Lindmayer, M.; Stege, M. (Technische Univ. Braunschweig (Germany, F.R.). Inst. fuer Elektrische Energieanlagen)

    1991-07-01

    Algorithms for early detection and prevention of short circuits are presented. Data on current levels and steepness in the a.c. network to be protected are evaluated by microcomputers. In particular, a simplified low-voltage grid is considered whose load circuit is formed in normal conditions by a serial R-L circuit. An optimum short-circuit detection algorithm is proposed for this network, which forecasts a current value from the current and steepness signals and compares this value with a limiting value. (orig.).

  11. Combined use of correlation dimension and entropy as discriminating measures for time series analysis

    Science.gov (United States)

    Harikrishnan, K. P.; Misra, R.; Ambika, G.

    2009-09-01

    We show that the combined use of correlation dimension (D2) and correlation entropy (K2) as discriminating measures can extract a more accurate information regarding the different types of noise present in a time series data. For this, we make use of an algorithmic approach for computing D2 and K2 proposed by us recently [Harikrishnan KP, Misra R, Ambika G, Kembhavi AK. Physica D 2006;215:137; Harikrishnan KP, Ambika G, Misra R. Mod Phys Lett B 2007;21:129; Harikrishnan KP, Misra R, Ambika G. Pramana - J Phys, in press], which is a modification of the standard Grassberger-Proccacia scheme. While the presence of white noise can be easily identified by computing D2 of data and surrogates, K2 is a better discriminating measure to detect colored noise in the data. Analysis of time series from a real world system involving both white and colored noise is presented as evidence. To our knowledge, this is the first time that such a combined analysis is undertaken on a real world data.

  12. Non-contact Real-time heart rate measurements based on high speed circuit technology research

    Science.gov (United States)

    Wu, Jizhe; Liu, Xiaohua; Kong, Lingqin; Shi, Cong; Liu, Ming; Hui, Mei; Dong, Liquan; Zhao, Yuejin

    2015-08-01

    In recent years, morbidity and mortality of the cardiovascular or cerebrovascular disease, which threaten human health greatly, increased year by year. Heart rate is an important index of these diseases. To address this status, the paper puts forward a kind of simple structure, easy operation, suitable for large populations of daily monitoring non-contact heart rate measurement. In the method we use imaging equipment video sensitive areas. The changes of light intensity reflected through the image grayscale average. The light change is caused by changes in blood volume. We video the people face which include the sensitive areas (ROI), and use high-speed processing circuit to save the video as AVI format into memory. After processing the whole video of a period of time, we draw curve of each color channel with frame number as horizontal axis. Then get heart rate from the curve. We use independent component analysis (ICA) to restrain noise of sports interference, realized the accurate extraction of heart rate signal under the motion state. We design an algorithm, based on high-speed processing circuit, for face recognition and tracking to automatically get face region. We do grayscale average processing to the recognized image, get RGB three grayscale curves, and extract a clearer pulse wave curves through independent component analysis, and then we get the heart rate under the motion state. At last, by means of compare our system with Fingertip Pulse Oximeter, result show the system can realize a more accurate measurement, the error is less than 3 pats per minute.

  13. CAMAC-compatible differential pulse discriminator-counter

    International Nuclear Information System (INIS)

    Tselikov, I.V.

    1988-01-01

    A differential pulse discriminator-counter for a Moessbauer spectrometer is described. Input pulses are collected according to the following algorithm; a pulse is admitted into the channel depending on whether or not the preceding pulse fell into the discrimination window. The circuit does not contain delay lines to allow for the delay lines to allow for the delay of the signal from the upper-level discriminator with respect to the signal from the lower-level discriminator due to the finite rise time of the input pulses, which makes it possible to reduce the dead time of the discriminator to the actuation time of the threshold circuits. The pulse count rate is 150 MHz, the input amplitude is +/-3 V, the dead time is 6 nsec, and the delay from input to output is 14 nsec. The unit is CAMAC-compatible

  14. Analog Integrated Circuit Design for Spike Time Dependent Encoder and Reservoir in Reservoir Computing Processors

    Science.gov (United States)

    2018-01-01

    HAS BEEN REVIEWED AND IS APPROVED FOR PUBLICATION IN ACCORDANCE WITH ASSIGNED DISTRIBUTION STATEMENT. FOR THE CHIEF ENGINEER : / S / / S...bridged high-performance computing, nanotechnology , and integrated circuits & systems. 15. SUBJECT TERMS neuromorphic computing, neuron design, spike...multidisciplinary effort encompassed high-performance computing, nanotechnology , integrated circuits, and integrated systems. The project’s architecture was

  15. Full Wave Analysis of Passive Microwave Monolithic Integrated Circuit Devices Using a Generalized Finite Difference Time Domain (GFDTD) Algorithm

    Science.gov (United States)

    Lansing, Faiza S.; Rascoe, Daniel L.

    1993-01-01

    This paper presents a modified Finite-Difference Time-Domain (FDTD) technique using a generalized conformed orthogonal grid. The use of the Conformed Orthogonal Grid, Finite Difference Time Domain (GFDTD) enables the designer to match all the circuit dimensions, hence eliminating a major source o error in the analysis.

  16. Real-time monitoring of a microbial electrolysis cell using an electrical equivalent circuit model.

    Science.gov (United States)

    Hussain, S A; Perrier, M; Tartakovsky, B

    2018-04-01

    Efforts in developing microbial electrolysis cells (MECs) resulted in several novel approaches for wastewater treatment and bioelectrosynthesis. Practical implementation of these approaches necessitates the development of an adequate system for real-time (on-line) monitoring and diagnostics of MEC performance. This study describes a simple MEC equivalent electrical circuit (EEC) model and a parameter estimation procedure, which enable such real-time monitoring. The proposed approach involves MEC voltage and current measurements during its operation with periodic power supply connection/disconnection (on/off operation) followed by parameter estimation using either numerical or analytical solution of the model. The proposed monitoring approach is demonstrated using a membraneless MEC with flow-through porous electrodes. Laboratory tests showed that changes in the influent carbon source concentration and composition significantly affect MEC total internal resistance and capacitance estimated by the model. Fast response of these EEC model parameters to changes in operating conditions enables the development of a model-based approach for real-time monitoring and fault detection.

  17. Timing properties and pulse shape discrimination of LAB-based liquid scintillator

    International Nuclear Information System (INIS)

    Li Xiaobo; Xiao Hualin; Cao Jun; Li Jin; Heng Yuekun; Ruan Xichao

    2011-01-01

    Linear Alkyl Benzene (LAB) is a promising liquid scintillator solvent in neutrino experiments because it has many appealing properties. The timing properties of LAB-based liquid scintillator have been studied through ultraviolet and ionization excitation in this study. The decay time of LAB, PPO and bis-MSB is found to be 48.6 ns, 1.55 ns and 1.5 ns, respectively. A model can describe the absorption and re-emission process between PPO and bis-MSB perfectly. The energy transfer time between LAB and PPO with different concentrations can be obtained via another model. We also show that the LAB-based liquid scintillator has good (n, γ) and (α, γ) discrimination power. (authors)

  18. Does Perceived Racial Discrimination Predict Changes in Psychological Distress and Substance Use Over Time? An Examination among Black Emerging Adults

    OpenAIRE

    Hurd, Noelle M.; Varner, Fatima A.; Caldwell, Cleopatra H.; Zimmerman, Marc A.

    2014-01-01

    We assessed whether perceived discrimination predicted changes in psychological distress and substance use over time and whether psychological distress and substance use predicted change in perceived discrimination over time. We also assessed whether associations between these constructs varied by gender. Our sample included 607 Black emerging adults (53% female) followed for four years. Participants reported the frequency with which they had experienced racial hassles during the past year, s...

  19. Chemical discrimination of lubricant marketing types using direct analysis in real time time-of-flight mass spectrometry.

    Science.gov (United States)

    Maric, Mark; Harvey, Lauren; Tomcsak, Maren; Solano, Angelique; Bridge, Candice

    2017-06-30

    In comparison to other violent crimes, sexual assaults suffer from very low prosecution and conviction rates especially in the absence of DNA evidence. As a result, the forensic community needs to utilize other forms of trace contact evidence, like lubricant evidence, in order to provide a link between the victim and the assailant. In this study, 90 personal bottled and condom lubricants from the three main marketing types, silicone-based, water-based and condoms, were characterized by direct analysis in real time time of flight mass spectrometry (DART-TOFMS). The instrumental data was analyzed by multivariate statistics including hierarchal cluster analysis, principal component analysis, and linear discriminant analysis. By interpreting the mass spectral data with multivariate statistics, 12 discrete groupings were identified, indicating inherent chemical diversity not only between but within the three main marketing groups. A number of unique chemical markers, both major and minor, were identified, other than the three main chemical components (i.e. PEG, PDMS and nonoxynol-9) currently used for lubricant classification. The data was validated by a stratified 20% withheld cross-validation which demonstrated that there was minimal overlap between the groupings. Based on the groupings identified and unique features of each group, a highly discriminating statistical model was then developed that aims to provide the foundation for the development of a forensic lubricant database that may eventually be applied to casework. Copyright © 2017 John Wiley & Sons, Ltd. Copyright © 2017 John Wiley & Sons, Ltd.

  20. A Better Criterion for the Discharging Time in an RC Circuit

    Science.gov (United States)

    Lima, Fabio M. S.

    2015-01-01

    When all parts of an electric circuit are at the same potential, no electric current flows and it is said to be in equilibrium. Otherwise, a current will flow from the higher potential parts to the lower ones, as when we make contact between the plates of a charged capacitor. The resulting discharging process towards equilibrium is a common phenomenon in electricity labs, as well as a topic covered in introductory physics, but some questions are not answered, e.g., could we establish a good criterion for the "end" of the charge transfer process? If so, typically how long does it take for electric equilibrium to be reached? The absence of these questions in textbooks and lab manuals has bothered me since my own undergraduate studies because, as the usual theory, in which charge is treated as a continuous, rather than discrete, parameter, predicts an exponential decay for the charge stored in the capacitor, rigorously speaking we should wait an infinitely long time for finding a complete equilibrium.1 Fortunately, when teaching experimental physics last year, I was asked about these very questions, which motivated me to search for a simple answer that could be adopted universally for measuring the "lifetime" of any physical quantity that decays exponentially in time.

  1. Real-time emulation of neural images in the outer retinal circuit.

    Science.gov (United States)

    Hasegawa, Jun; Yagi, Tetsuya

    2008-12-01

    We describe a novel real-time system that emulates the architecture and functionality of the vertebrate retina. This system reconstructs the neural images formed by the retinal neurons in real time by using a combination of analog and digital systems consisting of a neuromorphic silicon retina chip, a field-programmable gate array, and a digital computer. While the silicon retina carries out the spatial filtering of input images instantaneously, using the embedded resistive networks that emulate the receptive field structure of the outer retinal neurons, the digital computer carries out the temporal filtering of the spatially filtered images to emulate the dynamical properties of the outer retinal circuits. The emulations of the neural image, including 128 x 128 bipolar cells, are carried out at a frame rate of 62.5 Hz. The emulation of the response to the Hermann grid and a spot of light and an annulus of lights has demonstrated that the system responds as expected by previous physiological and psychophysical observations. Furthermore, the emulated dynamics of neural images in response to natural scenes revealed the complex nature of retinal neuron activity. We have concluded that the system reflects the spatiotemporal responses of bipolar cells in the vertebrate retina. The proposed emulation system is expected to aid in understanding the visual computation in the retina and the brain.

  2. Robust and Energy-Efficient Ultra-Low-Voltage Circuit Design under Timing Constraints in 65/45 nm CMOS

    Directory of Open Access Journals (Sweden)

    David Bol

    2011-01-01

    Full Text Available Ultra-low-voltage operation improves energy efficiency of logic circuits by a factor of 10×, at the expense of speed, which is acceptable for applications with low-to-medium performance requirements such as RFID, biomedical devices and wireless sensors. However, in 65/45 nm CMOS, variability and short-channel effects significantly harm robustness and timing closure of ultra-low-voltage circuits by reducing noise margins and jeopardizing gate delays. The consequent guardband on the supply voltage to meet a reasonable manufacturing yield potentially ruins energy efficiency. Moreover, high leakage currents in these technologies degrade energy efficiency in case of long stand-by periods. In this paper, we review recently published techniques to design robust and energy-efficient ultra-low-voltage circuits in 65/45 nm CMOS under relaxed yet strict timing constraints.

  3. A real-time neutron-gamma discriminator based on the support vector machine method for the time-of-flight neutron spectrometer

    Science.gov (United States)

    Wei, ZHANG; Tongyu, WU; Bowen, ZHENG; Shiping, LI; Yipo, ZHANG; Zejie, YIN

    2018-04-01

    A new neutron-gamma discriminator based on the support vector machine (SVM) method is proposed to improve the performance of the time-of-flight neutron spectrometer. The neutron detector is an EJ-299-33 plastic scintillator with pulse-shape discrimination (PSD) property. The SVM algorithm is implemented in field programmable gate array (FPGA) to carry out the real-time sifting of neutrons in neutron-gamma mixed radiation fields. This study compares the ability of the pulse gradient analysis method and the SVM method. The results show that this SVM discriminator can provide a better discrimination accuracy of 99.1%. The accuracy and performance of the SVM discriminator based on FPGA have been evaluated in the experiments. It can get a figure of merit of 1.30.

  4. The noise-time of response compromise in d.c. period meters. A new type of circuit (1961); Le compromis bruit-temps de reponse dans les periodemetres a courant continu. un nouveau type de circuit (1961)

    Energy Technology Data Exchange (ETDEWEB)

    Friedling, G [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1961-07-01

    The report compares the characteristics of three period meter circuits: - a linear circuit - a circuit which is non-linear according to the nuclear reactor period - a circuit which is non-linear according to the period and the power of the reactor. This last type of reactor has a fast time of response if the power is high or if the period is short, and it has a slow time of response when the power is low and the period long; this system makes it possible to maintain the noise at an acceptable level under all normal working conditions of the reactor. (author) [French] Le rapport compare les caracteristiques de trois circuits de periodemetres: - un circuit lineaire; - un circuit non lineaire selon la periode du reacteur nucleaire; - un circuit non lineaire selon la periode et la puissance du reacteur. Ce dernier type de circuit a un court temps de reponse si la puissance est faible et la periode grande; ce systeme permet de limiter le bruit a des niveaux acceptables dans toutes les conditions normales de fonctionnement du reacteur. (auteur)

  5. Involuntary memories of emotional scenes: The effects of cue discriminability and emotion over time

    DEFF Research Database (Denmark)

    Staugaard, Søren Risløv; Berntsen, Dorthe

    2014-01-01

    a range of clinical disorders, there is no broadly agreed upon explanation of their underlying mechanisms and no successful experimental simulations of their retrieval. In a series of experiments, we experimentally manipulated the activation of involuntary episodic memories for emotional and neutral...... scenes and predicted their activation on the basis of manipulations carried out at encoding and retrieval. Our findings suggest that the interplay between cue discriminability at the time of retrieval and emotional arousal at the time of encoding are crucial for explaining intrusive memories following...... negative events. While cue distinctiveness is important directly following encoding of the scenes, emotional intensity influences retrieval after delays of 24 hr and 1 week. Voluntary remembering follows the same pattern as involuntary remembering. Our results suggest an explanatory model of intrusive...

  6. Improvement of CPU time of Linear Discriminant Function based on MNM criterion by IP

    Directory of Open Access Journals (Sweden)

    Shuichi Shinmura

    2014-05-01

    Full Text Available Revised IP-OLDF (optimal linear discriminant function by integer programming is a linear discriminant function to minimize the number of misclassifications (NM of training samples by integer programming (IP. However, IP requires large computation (CPU time. In this paper, it is proposed how to reduce CPU time by using linear programming (LP. In the first phase, Revised LP-OLDF is applied to all cases, and all cases are categorized into two groups: those that are classified correctly or those that are not classified by support vectors (SVs. In the second phase, Revised IP-OLDF is applied to the misclassified cases by SVs. This method is called Revised IPLP-OLDF.In this research, it is evaluated whether NM of Revised IPLP-OLDF is good estimate of the minimum number of misclassifications (MNM by Revised IP-OLDF. Four kinds of the real data—Iris data, Swiss bank note data, student data, and CPD data—are used as training samples. Four kinds of 20,000 re-sampling cases generated from these data are used as the evaluation samples. There are a total of 149 models of all combinations of independent variables by these data. NMs and CPU times of the 149 models are compared with Revised IPLP-OLDF and Revised IP-OLDF. The following results are obtained: 1 Revised IPLP-OLDF significantly improves CPU time. 2 In the case of training samples, all 149 NMs of Revised IPLP-OLDF are equal to the MNM of Revised IP-OLDF. 3 In the case of evaluation samples, most NMs of Revised IPLP-OLDF are equal to NM of Revised IP-OLDF. 4 Generalization abilities of both discriminant functions are concluded to be high, because the difference between the error rates of training and evaluation samples are almost within 2%.   Therefore, Revised IPLP-OLDF is recommended for the analysis of big data instead of Revised IP-OLDF. Next, Revised IPLP-OLDF is compared with LDF and logistic regression by 100-fold cross validation using 100 re-sampling samples. Means of error rates of

  7. Open-circuit respirometry: real-time, laboratory-based systems.

    Science.gov (United States)

    Ward, Susan A

    2018-05-04

    This review explores the conceptual and technological factors integral to the development of laboratory-based, automated real-time open-circuit mixing-chamber and breath-by-breath (B × B) gas-exchange systems, together with considerations of assumptions and limitations. Advances in sensor technology, signal analysis, and digital computation led to the emergence of these technologies in the mid-20th century, at a time when investigators were beginning to recognise the interpretational advantages of nonsteady-state physiological-system interrogation in understanding the aetiology of exercise (in)tolerance in health, sport, and disease. Key milestones include the 'Auchincloss' description of an off-line system to estimate alveolar O 2 uptake B × B during exercise. This was followed by the first descriptions of real-time automated O 2 uptake and CO 2 output B × B measurement by Beaver and colleagues and by Linnarsson and Lindborg, and mixing-chamber measurement by Wilmore and colleagues. Challenges to both approaches soon emerged: e.g., the influence of mixing-chamber washout kinetics on mixed-expired gas concentration determination, and B × B alignment of gas-concentration signals with respired flow. The challenging algorithmic and technical refinements required for gas-exchange estimation at the alveolar level have also been extensively explored. In conclusion, while the technology (both hardware and software) underpinning real-time automated gas-exchange measurement has progressively advanced, there are still concerns regarding accuracy especially under the challenging conditions of changing metabolic rate.

  8. Simulation of the Universal-Time Diurnal Variation of the Global Electric Circuit Charging Rate

    Science.gov (United States)

    Mackerras, D.; Darvenzia, M.; Orville, R. E.; Williams, E. R.; Goodman, S. J.

    1999-01-01

    A global lightning model that includes diurnal and annual lightning variation, and total flash density versus latitude for each major land and ocean, has been used as the basis for simulating the global electric circuit charging rate. A particular objective has been to reconcile the difference in amplitude ratios [AR=(max-min)/mean] between global lightning diurnal variation (AR approx. = 0.8) and the diurnal variation of typical atmospheric potential gradient curves (AR approx. = 0.35). A constraint on the simulation is that the annual mean charging current should be about 1000 A. The global lightning model shows that negative ground flashes can contribute, at most, about 10-15% of the required current. For the purpose of the charging rate simulation, it was assumed that each ground flash contributes 5 C to the charging process. It was necessary to assume that all electrified clouds contribute to charging by means other than lightning, that the total flash rate can serve as an indirect indicator of the rate of charge transfer, and that oceanic electrified clouds contribute to charging even though they are relatively inefficient in producing lightning. It was also found necessary to add a diurnally invariant charging current component. By trial and error it was found that charging rate diurnal variation curves in Universal time (UT) could be produced with amplitude ratios and general shapes similar to those of the potential gradient diurnal variation curves measured over ocean and arctic regions during voyages of the Carnegie Institute research vessels.

  9. Analog circuit design designing dynamic circuit response

    CERN Document Server

    Feucht, Dennis

    2010-01-01

    This second volume, Designing Dynamic Circuit Response builds upon the first volume Designing Amplifier Circuits by extending coverage to include reactances and their time- and frequency-related behavioral consequences.

  10. Development of a non-delay-line constant-fraction discriminator

    International Nuclear Information System (INIS)

    Yang Tao; Zhao Bo; Zhang Chi

    2002-01-01

    A Non-Delay-Line Constant-Fraction Discriminator (CFD) timing circuit is introduced. The delay line in the CFD is replaced with a low pass filter in this simplified circuit. The timing resolution of the CFD is better than 150 ps

  11. Real-time 2.5  Gbit/s spatial circuit switching on W-band wireless links

    DEFF Research Database (Denmark)

    Rodríguez, Sebastián; Morales Vicente, Alvaro; Gallardo, Omar

    2017-01-01

    A spatial circuit switching system based on a beam steering application for W-band wireless links is proposed and experimentally demonstrated. The system enables two simultaneous transmissions of a 2.5 Gbit∕s data signal over a carrier of 81 GHz, while allowing the receiver to dynamically switch...... between them. The performance of the system is tested with the real-time measurements of the BER, achieving values below the FEC limit for 7% of overhead and serving to prove the viability of wireless spatial circuit switching in the next generation of wireless access networks....

  12. Evaluation of a timing integrated circuit architecture for continuous crystal and SiPM based PET systems

    OpenAIRE

    Monzó Ferrer, José María; Ros García, Ana; Herrero Bosch, Vicente; Perino Vicentini, Ivan Virgilio; Aliaga Varea, Ramón José; Gadea Gironés, Rafael; Colom Palero, Ricardo José

    2013-01-01

    Improving timing resolution in positron emission tomography (PET), thus having fine time information of the detected pulses, is important to increase the reconstructed images signal to noise ratio (SNR) [1]. In the present work, an integrated circuit topology for time extraction of the incoming pulses is evaluated. An accurate simulation including the detector physics and the electronics with different configurations has been developed. The selected architecture is intended for a PET sys...

  13. Does perceived racial discrimination predict changes in psychological distress and substance use over time? An examination among Black emerging adults.

    Science.gov (United States)

    Hurd, Noelle M; Varner, Fatima A; Caldwell, Cleopatra H; Zimmerman, Marc A

    2014-07-01

    We assessed whether perceived discrimination predicted changes in psychological distress and substance use over time and whether psychological distress and substance use predicted change in perceived discrimination over time. We also assessed whether associations between these constructs varied by gender. Our sample included 607 Black emerging adults (53% female) followed for 4 years. Participants reported the frequency with which they had experienced racial hassles during the past year, symptoms of anxiety and depression during the past week, and cigarette and alcohol use during the past 30 days. We estimated a series of latent growth models to test our study hypotheses. We found that the intercept of perceived discrimination predicted the linear slopes of anxiety symptoms, depressive symptoms, and alcohol use. We did not find any associations between the intercept factors of our mental health or substance use variables and the perceived discrimination linear slope factor. We found limited differences across paths by gender. Our findings suggest a temporal ordering in the associations among perceived racial discrimination, psychological distress, and alcohol use over time among emerging adults. Further, our findings suggest that perceived racial discrimination may be similarly harmful among men and women. (PsycINFO Database Record (c) 2014 APA, all rights reserved).

  14. Action Video Games Improve Direction Discrimination of Parafoveal Translational Global Motion but Not Reaction Times.

    Science.gov (United States)

    Pavan, Andrea; Boyce, Matthew; Ghin, Filippo

    2016-10-01

    Playing action video games enhances visual motion perception. However, there is psychophysical evidence that action video games do not improve motion sensitivity for translational global moving patterns presented in fovea. This study investigates global motion perception in action video game players and compares their performance to that of non-action video game players and non-video game players. Stimuli were random dot kinematograms presented in the parafovea. Observers discriminated the motion direction of a target random dot kinematogram presented in one of the four visual quadrants. Action video game players showed lower motion coherence thresholds than the other groups. However, when the task was performed at threshold, we did not find differences between groups in terms of distributions of reaction times. These results suggest that action video games improve visual motion sensitivity in the near periphery of the visual field, rather than speed response. © The Author(s) 2016.

  15. The effects of meritocracy beliefs on women's well-being after first-time gender discrimination.

    Science.gov (United States)

    Foster, Mindi D; Tsarfati, E Micha

    2005-12-01

    This study examined how meritocracy beliefs may buffer women from the negative psychological effects of an acute situation of gender discrimination. Although some research indirectly suggests that believing that meritocracy exists may increase wellbeing, group consciousness theories suggest that disbelieving that meritocracy exists will enhance psychological adjustment to gender discrimination. Women who reported little past experience with discrimination, and either believed or disbelieved that meritocracy exists, were exposed to either a laboratory situation of discrimination or a nondiscrimination failure (control) condition. Consistent with group consciousness theories, women experiencing discrimination reported greater well-being if they disbelieved that meritocracy exists than if they were believers. In contrast, women in the control condition reported greater wellbeing if they believed that meritocracy exists than if they were disbelievers. Implications for coping with discrimination are discussed.

  16. Real time n/γ discrimination for the JET neutron profile monitor

    Energy Technology Data Exchange (ETDEWEB)

    Riva, M., E-mail: marco.riva@enea.it [Associazione EURATOM-ENEA sulla Fusione, C.P. 65, Frascati I-00044, Roma (Italy); Esposito, B.; Marocco, D.; Belli, F. [Associazione EURATOM-ENEA sulla Fusione, C.P. 65, Frascati I-00044, Roma (Italy); Syme, B. [EURATOM/CCFE Fusion Association, OX14 3DB Abingdon (United Kingdom); Giacomelli, L. [Dipartimento di Fisica, Università degli Studi di Milano-Bicocca (Italy); Istituto di Fisica del Plasma, Associazione EURATOM-ENEA-CNR, 20100 Milano (Italy); JET-EFDA, Culham Science Centre, OX14 3DB Abingdon (United Kingdom)

    2013-10-15

    Highlights: ► Development of a pulse oriented acquisition system able for the JET neutron profile monitor to separate neutron and gamma pulses. ► Description of the FPGA hardware architecture. ► Comparison between the off-line and real time neutron count rates from the last JET experimental campaign. ► Estimate of the maximum sustainable count rate of the system. ► Statistical analysis of neutron measurements from JET neutron profile monitor and neutron monitors. -- Abstract: The JET neutron profile monitor provides the measurement of the neutron flux along 19 collimated lines of sight from which the neutron emissivity profile can be obtained through reconstruction based on inversion methods. The neutron detectors are liquid organic scintillators featuring n/γ pulse shape discrimination. A recent digital upgrade of the neutron profile monitor acquisition system (200 MSamples/s sampling rate per channel, 14 bit resolution) offers new real-time capabilities. An algorithm performing real-time n/γ discrimination by means of the charge comparison method is implemented in the acquisition system FPGA. The algorithm produces two distinct count rates (n and γ) that are sent to the JET real time network ready for control applications and are simultaneously stored into the JET archive together with all the samples of each pulse. The paper describes the architecture of the FPGA implementation and reports the analysis of data collected during the 2011–2012 JET campaigns. The comparison between the real-time and post-processed (off-line) neutron count rates shows an agreement within 5% for all 19 detectors. Moreover, it is shown that the maximum count rate sustainable by the acquisition system when storing raw data (∼900 kHz as evaluated in laboratory tests) can be extended up to 5 MHz when using the real-time implementation with no local data storage. Finally, a statistical analysis of the ratio between the line-integrated measurements from the neutron profile

  17. Time to address gender discrimination and inequality in the health workforce

    OpenAIRE

    Newman, Constance

    2014-01-01

    Gender is a key factor operating in the health workforce. Recent research evidence points to systemic gender discrimination and inequalities in health pre-service and in-service education and employment systems. Human resources for health (HRH) leaders’ and researchers’ lack of concerted attention to these inequalities is striking, given the recognition of other forms of discrimination in international labour rights and employment law discourse. If not acted upon, gender discrimination and in...

  18. A circuit-level analysis of third order intermodulation mechanisms in CMOS mixers using time-invariant power and Volterra series

    NARCIS (Netherlands)

    Sakian, P.; Mahmoudi, R.; Roermund, van A.H.M.

    2011-01-01

    An in-depth analysis is performed on the third-order intermodulation distortions (IMD3) in the switching pair of active CMOS mixers. The nonlinear time-varying switching pair is described by a hypothetical circuit composed of a nonlinear time-invariant circuit cascaded with a linear time-varying

  19. Plug-and-Play Multicellular Circuits with Time-Dependent Dynamic Responses.

    Science.gov (United States)

    Urrios, Arturo; Gonzalez-Flo, Eva; Canadell, David; de Nadal, Eulàlia; Macia, Javier; Posas, Francesc

    2018-04-20

    Synthetic biology studies aim to develop cellular devices for biomedical applications. These devices, based on living instead of electronic or electromechanic technology, might provide alternative treatments for a wide range of diseases. However, the feasibility of these devices depends, in many cases, on complex genetic circuits that must fulfill physiological requirements. In this work, we explored the potential of multicellular architectures to act as an alternative to complex circuits for implementation of new devices. As a proof of concept, we developed specific circuits for insulin or glucagon production in response to different glucose levels. Here, we show that fundamental features, such as circuit's affinity or sensitivity, are dependent on the specific configuration of the multicellular consortia, providing a method for tuning these properties without genetic engineering. As an example, we have designed and built circuits with an incoherent feed-forward loop architecture (FFL) that can be easily adjusted to generate single pulse responses. Our results might serve as a blueprint for future development of cellular devices for glycemia regulation in diabetic patients.

  20. Integrated circuits with emitter coupling and their application in nanosecond nuclear electronics

    International Nuclear Information System (INIS)

    Basiladze, S.G.

    1976-01-01

    Principal static and dynamic characteristics are considered of integrated circuits with emitter coupling, as well as problems of signal transmission. Diagrams are given of amplifiers, discriminators, time interval drivers, generators, etc. Systems and units of nanosecond electronics employing integrated circuits with emitter coupling are briefly described

  1. Real-time odor discrimination using a bioelectronic sensor array based on the insect electroantennogram

    International Nuclear Information System (INIS)

    Myrick, A J; Hetling, J R; Park, K-C; Baker, T C

    2008-01-01

    Current trends in artificial nose research are strongly influenced by knowledge of biological olfactory systems. Insects have evolved over millions of years to detect and maneuver toward a food source or mate, or away from predators. The insect olfactory system is able to identify volatiles on a time scale that matches their ability to maneuver. Here, biological olfactory sense organs, insect antennae, have been exploited in a hybrid-device biosensor, demonstrating the ability to identify individual strands of odor in a plume passing over the sensor on a sub-second time scale. A portable system was designed to utilize the electrophysiological responses recorded from a sensor array composed of male or female antennae from four or eight different species of insects (a multi-channel electroantennogram, EAG). A computational analysis strategy that allows discrimination between odors in real time is described in detail. Following a training period, both semi-parametric and k-nearest neighbor (k-NN) classifiers with the ability to discard ambiguous responses are applied toward the classification of up to eight odors. EAG responses to individual strands in an odor plume are classified or discarded as ambiguous with a delay (sensor response to classification report) on the order of 1 s. The dependence of classification error rate on several parameters is described. Finally, the performance of the approach is compared to that of a minimal conditional risk classifier

  2. 5 CFR 1201.156 - Time for processing appeals involving allegations of discrimination.

    Science.gov (United States)

    2010-01-01

    ... in appeal. When an appellant alleges prohibited discrimination in the appeal, the judge will decide... appeal, but has raised the issue later in the proceeding, the judge will decide both the issue of... remanded to agency. When the judge remands an issue of discrimination to the agency, adjudication will be...

  3. High-performance integrated pick-up circuit for SPAD arrays in time-correlated single photon counting

    Science.gov (United States)

    Acconcia, Giulia; Cominelli, Alessandro; Peronio, Pietro; Rech, Ivan; Ghioni, Massimo

    2017-05-01

    The analysis of optical signals by means of Single Photon Avalanche Diodes (SPADs) has been subject to a widespread interest in recent years. The development of multichannel high-performance Time Correlated Single Photon Counting (TCSPC) acquisition systems has undergone a fast trend. Concerning the detector performance, best in class results have been obtained resorting to custom technologies leading also to a strong dependence of the detector timing jitter from the threshold used to determine the onset of the photogenerated current flow. In this scenario, the avalanche current pick-up circuit plays a key role in determining the timing performance of the TCSPC acquisition system, especially with a large array of SPAD detectors because of electrical crosstalk issues. We developed a new current pick-up circuit based on a transimpedance amplifier structure able to extract the timing information from a 50-μm-diameter custom technology SPAD with a state-of-art timing jitter as low as 32ps and suitable to be exploited with SPAD arrays. In this paper we discuss the key features of this structure and we present a new version of the pick-up circuit that also provides quenching capabilities in order to minimize the number of interconnections required, an aspect that becomes more and more crucial in densely integrated systems.

  4. Fast neutron tomography with real-time pulse-shape discrimination in organic scintillation detectors

    Energy Technology Data Exchange (ETDEWEB)

    Joyce, Malcolm J., E-mail: m.joyce@lancaster.ac.uk [Department of Engineering, Lancaster University, Lancaster, Lancashire LA1 4YW (United Kingdom); Agar, Stewart [Department of Engineering, Lancaster University, Lancaster, Lancashire LA1 4YW (United Kingdom); Aspinall, Michael D. [Hybrid Instruments Ltd., Gordon Manley Building, Lancaster Environment Centre, Lancaster University, Lancaster LA1 4YW (United Kingdom); Beaumont, Jonathan S.; Colley, Edmund; Colling, Miriam; Dykes, Joseph; Kardasopoulos, Phoevos; Mitton, Katie [Department of Engineering, Lancaster University, Lancaster, Lancashire LA1 4YW (United Kingdom)

    2016-10-21

    A fast neutron tomography system based on the use of real-time pulse-shape discrimination in 7 organic liquid scintillation detectors is described. The system has been tested with a californium-252 source of dose rate 163 μSv/h at 1 m and neutron emission rate of 1.5×10{sup 7} per second into 4π and a maximum acquisition time of 2 h, to characterize two 100×100×100 mm{sup 3} concrete samples. The first of these was a solid sample and the second has a vertical, cylindrical void. The experimental data, supported by simulations with both Monte Carlo methods and MATLAB®, indicate that the presence of the internal cylindrical void, corners and inhomogeneities in the samples can be discerned. The potential for fast neutron assay of this type with the capability to probe hydrogenous features in large low-Z samples is discussed. Neutron tomography of bulk porous samples is achieved that combines effective penetration not possible with thermal neutrons in the absence of beam hardening.

  5. Time dependent charging of layer clouds in the global electric circuit

    Science.gov (United States)

    Zhou, Limin; Tinsley, Brian A.

    2012-09-01

    There is much observational data consistent with the hypothesis that the ionosphere-earth current density (Jz) in the global electric circuit, which is modulated by both solar activity and thunderstorm activity, affects atmospheric dynamics and cloud cover. One candidate mechanism involves Jz causing the accumulation of space charge on droplets and aerosol particles, that affects the rate of scavenging of the latter, notably those of Cloud Condensation Nuclei (CCN) and Ice Forming Nuclei (IFN) (Tinsley, 2008, 2010). Space charge is the difference, per unit volume, between total positive and total negative electrical charge that is on droplets, aerosol particles (including the CCN and IFN) and air ions. The cumulative effects of the scavenging in stratiform clouds and aerosol layers in an air mass over the lifetime of the aerosol particles of 1-10 days affects the concentration and size distribution of the CCN, so that in subsequent episodes of cloud formation (including deep convective clouds) there can be effects on droplet size distribution, coagulation, precipitation processes, and even storm dynamics.Because the time scales for charging for some clouds can be long compared to cloud lifetimes, the amount of charge at a given time, and its effect on scavenging, depend more on the charging rate than on the equilibrium charge that would eventually be attained. To evaluate this, a new time-dependent charging model has been developed. The results show that for typical altostratus clouds with typical droplet radii 10 μm and aerosol particles of radius of 0.04 μm, the time constant for charging in response to a change in Jz is about 800 s, which is comparable to cloud formation and dissipation timescales for some cloud situations. The charging timescale is found to be strong functions of altitude and aerosol concentration, with the time constant for droplet charging at 2 km in air with a high concentration of aerosols being about an hour, and for clouds at 10 km in

  6. Training haptic stiffness discrimination: time course of learning with or without visual information and knowledge of results.

    Science.gov (United States)

    Teodorescu, Kinneret; Bouchigny, Sylvain; Korman, Maria

    2013-08-01

    In this study, we explored the time course of haptic stiffness discrimination learning and how it was affected by two experimental factors, the addition of visual information and/or knowledge of results (KR) during training. Stiffness perception may integrate both haptic and visual modalities. However, in many tasks, the visual field is typically occluded, forcing stiffness perception to be dependent exclusively on haptic information. No studies to date addressed the time course of haptic stiffness perceptual learning. Using a virtual environment (VE) haptic interface and a two-alternative forced-choice discrimination task, the haptic stiffness discrimination ability of 48 participants was tested across 2 days. Each day included two haptic test blocks separated by a training block Additional visual information and/or KR were manipulated between participants during training blocks. Practice repetitions alone induced significant improvement in haptic stiffness discrimination. Between days, accuracy was slightly improved, but decision time performance was deteriorated. The addition of visual information and/or KR had only temporary effects on decision time, without affecting the time course of haptic discrimination learning. Learning in haptic stiffness discrimination appears to evolve through at least two distinctive phases: A single training session resulted in both immediate and latent learning. This learning was not affected by the training manipulations inspected. Training skills in VE in spaced sessions can be beneficial for tasks in which haptic perception is critical, such as surgery procedures, when the visual field is occluded. However, training protocols for such tasks should account for low impact of multisensory information and KR.

  7. Recent run-time experience and investigation of impurities in turbines circuit of Helium plant of SST-1

    International Nuclear Information System (INIS)

    Panchal, P.; Panchal, R.; Patel, R.

    2013-01-01

    One of the key sub-systems of Steady State superconducting Tokamak (SST-1) is cryogenic 1.3 kW at 4.5 K Helium refrigerator/liquefier system. The helium plant consists of 3 nos. of screw compressors, oil removal system, purifier and cold-box with 3 turbo expanders (turbines) and helium cold circulator. During the recent SST-1 plasma campaigns, we observed high pressure drop of the order of 3 bar between the wheel outlet of turbine A and the wheel inlet of turbine - B. This was significant higher values of pressures drop across turbines, which reduced the speed of turbine A and B and in turn reduced the overall plant capacity. The helium circuits in the plant have 10-micron filter at the mouth of turbine - B. Initially, major suspects of such high blockage are assumed to be air-impurity, dust particles or collapse of filter. Several breaks in plant operation have been taken to warm up the turbines circuits up to 90 K to remove condensation of air-impurities at filter. Still this exercise did not solve blockage of filter in turbine circuits. A detailed investigation exercise with air/water regeneration and rinsing of cold box as well as purification of helium gas in buffer tanks are carried out to remove air impurities from cold-box. A trial run of cold box was executed in liquefier mode with turbines up to cryogenic temperatures and solved blockage in turbine circuits. The paper describes run-time experience of helium plant with helium impurity in turbine circuits, methods to remove impurity, demonstration of turbine performance and lessons learnt during this operation. (author)

  8. Two-dimensional statistical linear discriminant analysis for real-time robust vehicle-type recognition

    Science.gov (United States)

    Zafar, I.; Edirisinghe, E. A.; Acar, S.; Bez, H. E.

    2007-02-01

    Automatic vehicle Make and Model Recognition (MMR) systems provide useful performance enhancements to vehicle recognitions systems that are solely based on Automatic License Plate Recognition (ALPR) systems. Several car MMR systems have been proposed in literature. However these approaches are based on feature detection algorithms that can perform sub-optimally under adverse lighting and/or occlusion conditions. In this paper we propose a real time, appearance based, car MMR approach using Two Dimensional Linear Discriminant Analysis that is capable of addressing this limitation. We provide experimental results to analyse the proposed algorithm's robustness under varying illumination and occlusions conditions. We have shown that the best performance with the proposed 2D-LDA based car MMR approach is obtained when the eigenvectors of lower significance are ignored. For the given database of 200 car images of 25 different make-model classifications, a best accuracy of 91% was obtained with the 2D-LDA approach. We use a direct Principle Component Analysis (PCA) based approach as a benchmark to compare and contrast the performance of the proposed 2D-LDA approach to car MMR. We conclude that in general the 2D-LDA based algorithm supersedes the performance of the PCA based approach.

  9. Investigating the time course of tactile reflexive attention using a non-spatial discrimination task.

    Science.gov (United States)

    Miles, Eleanor; Poliakoff, Ellen; Brown, Richard J

    2008-06-01

    Peripheral cues are thought to facilitate responses to stimuli presented at the same location because they lead to exogenous attention shifts. Facilitation has been observed in numerous studies of visual and auditory attention, but there have been only four demonstrations of tactile facilitation, all in studies with potential confounds. Three studies used a spatial (finger versus thumb) discrimination task, where the cue could have provided a spatial framework that might have assisted the discrimination of subsequent targets presented on the same side as the cue. The final study circumvented this problem by using a non-spatial discrimination; however, the cues were informative and interspersed with visual cues which may have affected the attentional effects observed. In the current study, therefore, we used a non-spatial tactile frequency discrimination task following a non-informative tactile white noise cue. When the target was presented 150 ms after the cue, we observed faster discrimination responses to targets presented on the same side compared to the opposite side as the cue; by 1000 ms, responses were significantly faster to targets presented on the opposite side to the cue. Thus, we demonstrated that tactile attentional facilitation can be observed in a non-spatial discrimination task, under unimodal conditions and with entirely non-predictive cues. Furthermore, we provide the first demonstration of significant tactile facilitation and tactile inhibition of return within a single experiment.

  10. Study of time dependence and spectral composition of the signal in circuit of ac electric point motors

    Directory of Open Access Journals (Sweden)

    S. Yu. Buryak

    2014-12-01

    Full Text Available Purpose. The paper is aimed to establish the dependence of changes in the time domain and spectral components of the current in the circuit of the AC electric point motor on its technical condition, to identify the common features for the same type of damage. It is necessary using the analysis of the received signals to carry out the remote diagnosis and determination of faults and defects of electric point motors. In addition it suggested to accelerate the process of the failure, malfunction and damage search. Authors propose the automated approach to the service of remote floor automation equipment, which is located in the envelope of trains. Reduction of the threat to life and health of staff by reducing the residence time in the zone of train movement. Reduce the impact of human factors on the result of service. Methodology. The paper studies the structure, parameters and characteristics, the operation and maintenance characteristics of the AC electric point motors. Determination of the main types of possible faults in the process depending on the operating conditions. Presentation of the electric motor as an object of diagnosis. Findings. The time dependences of the current in the circuit of electric point motor for its various states was obtained. The connection between the technical condition of electric point motor and the performance of current curve in time and spectral domains was established. The revealed deviations from the reference signal were justified. According to the obtained results it was made the conclusion. Originality. A method for diagnosing the state of the AC electric point motor by the time dependence and the spectral composition of the current in its circuit was proposed. The connection diagram to the motor windings based on non-infringement of electric parameters of connection circuit in the actual operating conditions was applied. Practical value. The obtained results suggest the possibility and feasibility of

  11. Third degree waiting time discrimination: optimal allocation of a public sector healthcare treatment under rationing by waiting.

    Science.gov (United States)

    Gravelle, Hugh; Siciliani, Luigi

    2009-08-01

    In many public healthcare systems treatments are rationed by waiting time. We examine the optimal allocation of a fixed supply of a given treatment between different groups of patients. Even in the absence of any distributional aims, welfare is increased by third degree waiting time discrimination: setting different waiting times for different groups waiting for the same treatment. Because waiting time imposes dead weight losses on patients, lower waiting times should be offered to groups with higher marginal waiting time costs and with less elastic demand for the treatment.

  12. Minority n out of m coincidence circuits for time-differential experiments with multi-detector arrays

    International Nuclear Information System (INIS)

    Braunsfurth, J.; Geske, K.

    1976-01-01

    Two n out of m minority coincidence circuits (n<=8, 15<=m<=31), employed for time-differential experiments are presented. Specifications like obtainable prompt coincidence resolution time, expandability to higher detector numbers m, implementation variants and their consequences, and some application modes are discussed. Hardware expenses on electronics for m-detector arrays usually rise nearly proportional to m factorial. In the coincidence system proposed here, the rise in hardware expenses can be reduced to slightly more than proportional to m, without sacrifice in experimental quality and flexibility. (Auth.)

  13. Man-portable Vector Time Domain EMI Sensor and Discrimination Processing

    Science.gov (United States)

    2012-04-16

    can also serve as as a discriminant. Q may be parametrized by a Pasion Oldenburg type model and/or combined with other parameters, for example from the...IEEE Trans. Geosci. Remote Sens., 43:1490–1498, July 2005. 4, 43 [23] S.D. Billings, L.R. Pasion , N. Lhomme, and D.W. Oldenburg. Discrimination at...Lhomme, L. R. Pasion , S. D. Billings, and D. W. Oldenburg. Inversion of frequency domain data collected in a magnetic setting for the detection of uxo

  14. A low walk double threshold discriminator for gas tracking devices

    International Nuclear Information System (INIS)

    Balla, A.; Benussi, L.; Bertani, M.; Bianco, S.; Corradi, G.; Fabbri, F. L.; Giannotti, P.; Giardoni, M.; Lucherini, V.; Pace, E.; Passamonti, L.; Pompili, F.; Russo, V.; Sarwar, S.; Tomassini, S.

    2001-01-01

    A 9U VME like double threshold discriminator has been designed and constructed at Frascati INFN (National Institute of Nuclear Physics) laboratories. Its aim is to process the signals arising from gas drift chambers, introducing a very small time walk (∼ 650 ps.). Each discriminator board houses 32 channels. Each channel is located on an independent printed circuit mounted on socket. This solution is very convenient for replacing faulty channels without loosing operation of the full board

  15. Reaction Time and Self-Report Psychopathological Assessment: Convergent and Discriminant Validity.

    Science.gov (United States)

    Holden, Ronald R.; Fekken, G. Cynthia

    The processing of incoming psychological information along the network, or schemata, of self-knowledge was studied to determine the convergent and discriminant validity of the patterns of schemata-specific response latencies. Fifty-three female and 52 male university students completed the Basic Personality Inventory (BPI). BPI scales assess…

  16. Time to address gender discrimination and inequality in the health workforce.

    Science.gov (United States)

    Newman, Constance

    2014-05-06

    Gender is a key factor operating in the health workforce. Recent research evidence points to systemic gender discrimination and inequalities in health pre-service and in-service education and employment systems. Human resources for health (HRH) leaders' and researchers' lack of concerted attention to these inequalities is striking, given the recognition of other forms of discrimination in international labour rights and employment law discourse. If not acted upon, gender discrimination and inequalities result in systems inefficiencies that impede the development of the robust workforces needed to respond to today's critical health care needs.This commentary makes the case that there is a clear need for sex- and age-disaggregated and qualitative data to more precisely illuminate gender-related trends and dynamics in the health workforce. Because of their importance for measurement, the paper also presents definitions and examples of sex or gender discrimination and offers specific case examples.At a broader level, the commentary argues that gender equality should be an HRH research, leadership, and governance priority, where the aim is to strengthen health pre-service and continuing professional education and employment systems to achieve better health systems outcomes, including better health coverage. Good HRH leadership, governance, and management involve recognizing the diversity of health workforces, acknowledging gender constraints and opportunities, eliminating gender discrimination and equalizing opportunity, making health systems responsive to life course events, and protecting health workers' labour rights at all levels. A number of global, national and institution-level actions are proposed to move the gender equality and HRH agendas forward.

  17. A VLSI front-end circuit for microstrip silicon detectors for medical imaging applications

    International Nuclear Information System (INIS)

    Beccherle, R.; Cisternino, A.; Guerra, A. Del; Folli, M.; Marchesini, R.; Bisogni, M.G.; Ceccopieri, A.; Rosso, V.; Stefanini, A.; Tripiccione, R.; Kipnis, I.

    1999-01-01

    An analog CMOS-Integrated Circuit has been developed as Front-End for a double-sided microstrip silicon detector. The IC processes and discriminates signals in the 5-30 keV energy range. Main features are low noise and precise timing information. Low noise is achieved by optimizing the cascoded integrator with the 8 pF detector capacitance and by using an inherently low noise 1.2 μm CMOS technology. Timing information is provided by a double discriminator architecture. The output of the circuit is a digital pulse. The leading edge is determined by a fixed threshold discriminator, while the trailing edge is provided by a zero crossing discriminator. In this paper we first describe the architecture of the Front-End chip. We then present the performance of the chip prototype in terms of noise, minimum discrimination threshold and time resolution

  18. Signal sampling circuit

    NARCIS (Netherlands)

    Louwsma, S.M.; Vertregt, Maarten

    2011-01-01

    A sampling circuit for sampling a signal is disclosed. The sampling circuit comprises a plurality of sampling channels adapted to sample the signal in time-multiplexed fashion, each sampling channel comprising a respective track-and-hold circuit connected to a respective analogue to digital

  19. Signal sampling circuit

    NARCIS (Netherlands)

    Louwsma, S.M.; Vertregt, Maarten

    2010-01-01

    A sampling circuit for sampling a signal is disclosed. The sampling circuit comprises a plurality of sampling channels adapted to sample the signal in time-multiplexed fashion, each sampling channel comprising a respective track-and-hold circuit connected to a respective analogue to digital

  20. Implementation on Electronic Circuits and RTR Pragmatical Adaptive Synchronization: Time-Reversed Uncertain Dynamical Systems' Analysis and Applications

    Directory of Open Access Journals (Sweden)

    Shih-Yu Li

    2013-01-01

    Full Text Available We expose the chaotic attractors of time-reversed nonlinear system, further implement its behavior on electronic circuit, and apply the pragmatical asymptotically stability theory to strictly prove that the adaptive synchronization of given master and slave systems with uncertain parameters can be achieved. In this paper, the variety chaotic motions of time-reversed Lorentz system are investigated through Lyapunov exponents, phase portraits, and bifurcation diagrams. For further applying the complex signal in secure communication and file encryption, we construct the circuit to show the similar chaotic signal of time-reversed Lorentz system. In addition, pragmatical asymptotically stability theorem and an assumption of equal probability for ergodic initial conditions (Ge et al., 1999, Ge and Yu, 2000, and Matsushima, 1972 are proposed to strictly prove that adaptive control can be accomplished successfully. The current scheme of adaptive control—by traditional Lyapunov stability theorem and Barbalat lemma, which are used to prove the error vector—approaches zero, as time approaches infinity. However, the core question—why the estimated or given parameters also approach to the uncertain parameters—remains without answer. By the new stability theory, those estimated parameters can be proved approaching the uncertain values strictly, and the simulation results are shown in this paper.

  1. Evaluation of a timing integrated circuit architecture for continuous crystal and SiPM based PET systems

    International Nuclear Information System (INIS)

    Monzo, J M; Ros, A; Herrero-Bosch, V; Perino, I V; Aliaga, R J; Gadea-Girones, R; Colom-Palero, R J

    2013-01-01

    Improving timing resolution in positron emission tomography (PET), thus having fine time information of the detected pulses, is important to increase the reconstructed images signal to noise ratio (SNR) [1]. In the present work, an integrated circuit topology for time extraction of the incoming pulses is evaluated. An accurate simulation including the detector physics and the electronics with different configurations has been developed. The selected architecture is intended for a PET system based on a continuous scintillation crystal attached to a SiPM array. The integrated circuit extracts the time stamp from the first few photons generated when the gamma-ray interacts with the scintillator, thus obtaining the best time resolution. To get the time stamp from the detected pulses, a time to digital converter (TDC) array based architecture has been proposed as in [2] or [3]. The TDC input stage uses a current comparator to transform the analog signal into a digital signal. Individually configurable trigger levels allow us to avoid false triggers due to signal noise. Using a TDC per SiPM configuration results in a very area consuming integrated circuit. One solution to this problem is to join several SiPM outputs to one TDC. This reduces the number of TDCs but, on the other hand, the first photons will be more difficult to be detected. For this reason, it is important to simulate how the time resolution is degraded when the number of TDCs is reduced. Following this criteria, the best configuration will be selected considering the trade-off between achievable time resolution and the cost per chip. A simulation is presented that uses Geant4 for simulation of the physics process and, for the electronic blocks, spice and Matlab. The Geant4 stage simulates the gamma-ray interaction with the scintillator, the photon shower generation and the first stages of the SiPM. The electronics simulation includes an electrical model of the SiPM array and all the integrated circuitry

  2. Non-destructive evaluation of the hidden voids in integrated circuit packages using terahertz time-domain spectroscopy

    International Nuclear Information System (INIS)

    Park, Sung-Hyeon; Kim, Hak-Sung; Jang, Jin-Wook

    2015-01-01

    In this work, a terahertz time-domain spectroscopy (THz-TDS) imaging technique was used as a non-destructive inspection method for detecting voids in integrated circuit (IC) packages. Transmission and reflection modes, with an angle of incidence of 30°, were used to detect voids in IC packages. The locations of the detected voids in the IC packages could be calculated by analyzing THz waveforms. Finally, voids that are positioned at the different interfaces in the IC package samples could be successfully detected and imaged. Therefore, this THz-TDS imaging technique is expected to be a promising technique for non-destructive evaluation of IC packages. (paper)

  3. Terahertz time-domain attenuated total reflection spectroscopy applied to the rapid discrimination of the botanical origin of honeys

    Science.gov (United States)

    Liu, Wen; Zhang, Yuying; Yang, Si; Han, Donghai

    2018-05-01

    A new technique to identify the floral resources of honeys is demanded. Terahertz time-domain attenuated total reflection spectroscopy combined with chemometrics methods was applied to discriminate different categorizes (Medlar honey, Vitex honey, and Acacia honey). Principal component analysis (PCA), cluster analysis (CA) and partial least squares-discriminant analysis (PLS-DA) have been used to find information of the botanical origins of honeys. Spectral range also was discussed to increase the precision of PLS-DA model. The accuracy of 88.46% for validation set was obtained, using PLS-DA model in 0.5-1.5 THz. This work indicated terahertz time-domain attenuated total reflection spectroscopy was an available approach to evaluate the quality of honey rapidly.

  4. Parameter estimation methods for gene circuit modeling from time-series mRNA data: a comparative study.

    Science.gov (United States)

    Fan, Ming; Kuwahara, Hiroyuki; Wang, Xiaolei; Wang, Suojin; Gao, Xin

    2015-11-01

    Parameter estimation is a challenging computational problem in the reverse engineering of biological systems. Because advances in biotechnology have facilitated wide availability of time-series gene expression data, systematic parameter estimation of gene circuit models from such time-series mRNA data has become an important method for quantitatively dissecting the regulation of gene expression. By focusing on the modeling of gene circuits, we examine here the performance of three types of state-of-the-art parameter estimation methods: population-based methods, online methods and model-decomposition-based methods. Our results show that certain population-based methods are able to generate high-quality parameter solutions. The performance of these methods, however, is heavily dependent on the size of the parameter search space, and their computational requirements substantially increase as the size of the search space increases. In comparison, online methods and model decomposition-based methods are computationally faster alternatives and are less dependent on the size of the search space. Among other things, our results show that a hybrid approach that augments computationally fast methods with local search as a subsequent refinement procedure can substantially increase the quality of their parameter estimates to the level on par with the best solution obtained from the population-based methods while maintaining high computational speed. These suggest that such hybrid methods can be a promising alternative to the more commonly used population-based methods for parameter estimation of gene circuit models when limited prior knowledge about the underlying regulatory mechanisms makes the size of the parameter search space vastly large. © The Author 2015. Published by Oxford University Press. For Permissions, please email: journals.permissions@oup.com.

  5. Discrimination of time-dependent inflow properties with a cooperative dynamical system.

    Science.gov (United States)

    Ueno, Hiroshi; Tsuruyama, Tatsuaki; Nowakowski, Bogdan; Górecki, Jerzy; Yoshikawa, Kenichi

    2015-10-01

    Many physical, chemical, and biological systems exhibit a cooperative or sigmoidal response with respect to the input. In biochemistry, such behavior is called an allosteric effect. Here, we demonstrate that a system with such properties can be used to discriminate the amplitude or frequency of an external periodic perturbation. Numerical simulations performed for a model sigmoidal kinetics illustrate that there exists a narrow range of frequencies and amplitudes within which the system evolves toward significantly different states. Therefore, observation of system evolution should provide information about the characteristics of the perturbation. The discrimination properties for periodic perturbation are generic. They can be observed in various dynamical systems and for different types of periodic perturbation.

  6. Rapid identification of ST131 Escherichia coli by a novel multiplex real-time allelic discrimination assay.

    Science.gov (United States)

    François, Patrice; Bonetti, Eve-Julie; Fankhauser, Carolina; Baud, Damien; Cherkaoui, Abdessalam; Schrenzel, Jacques; Harbarth, Stephan

    2017-09-01

    Escherichia coli sequence type 131 is increasingly described in severe hospital infections. We developed a rapid real-time allelic discrimination assay for the rapid identification of E. coli ST131 isolates. This rapid assay represents an affordable alternative to sequence-based strategies before completing characterization of potentially highly virulent isolates of E. coli. Copyright © 2017 Elsevier B.V. All rights reserved.

  7. High Performance Microaccelerometer with Wafer-level Hermetic Packaged Sensing Element and Continuous-time BiCMOS Interface Circuit

    International Nuclear Information System (INIS)

    Ko, Hyoungho; Park, Sangjun; Paik, Seung-Joon; Choi, Byoung-doo; Park, Yonghwa; Lee, Sangmin; Kim, Sungwook; Lee, Sang Chul; Lee, Ahra; Yoo, Kwangho; Lim, Jaesang; Cho, Dong-il

    2006-01-01

    A microaccelerometer with highly reliable, wafer-level packaged MEMS sensing element and fully differential, continuous time, low noise, BiCMOS interface circuit is fabricated. The MEMS sensing element is fabricated on a (111)-oriented SOI wafer by using the SBM (Sacrificial/Bulk Micromachining) process. To protect the silicon structure of the sensing element and enhance the reliability, a wafer level hermetic packaging process is performed by using a silicon-glass anodic bonding process. The interface circuit is fabricated using 0.8 μm BiCMOS process. The capacitance change of the MEMS sensing element is amplified by the continuous-time, fully-differential transconductance input amplifier. A chopper-stabilization architecture is adopted to reduce low-frequency noise including 1/f noise. The fabricated microaccelerometer has the total noise equivalent acceleration of 0.89 μg/√Hz, the bias instability of 490 μg, the input range of ±10 g, and the output nonlinearity of ±0.5 %FSO

  8. Autoregressive models as a tool to discriminate chaos from randomness in geoelectrical time series: an application to earthquake prediction

    Directory of Open Access Journals (Sweden)

    C. Serio

    1997-06-01

    Full Text Available The time dynamics of geoelectrical precursory time series has been investigated and a method to discriminate chaotic behaviour in geoelectrical precursory time series is proposed. It allows us to detect low-dimensional chaos when the only information about the time series comes from the time series themselves. The short-term predictability of these time series is evaluated using two possible forecasting approaches: global autoregressive approximation and local autoregressive approximation. The first views the data as a realization of a linear stochastic process, whereas the second considers the data points as a realization of a deterministic process, supposedly non-linear. The comparison of the predictive skill of the two techniques is a test to discriminate between low-dimensional chaos and random dynamics. The analyzed time series are geoelectrical measurements recorded by an automatic station located in Tito (Southern Italy in one of the most seismic areas of the Mediterranean region. Our findings are that the global (linear approach is superior to the local one and the physical system governing the phenomena of electrical nature is characterized by a large number of degrees of freedom. Power spectra of the filtered time series follow a P(f = F-a scaling law: they exhibit the typical behaviour of a broad class of fractal stochastic processes and they are a signature of the self-organized systems.

  9. Contribution of custom-designed integrated circuits to the electronic equipment of multiwire chambers

    International Nuclear Information System (INIS)

    Prunier, J.

    1977-01-01

    The first generations of circuits intended to equip the multiwire proportional chambers provided the user with logical type indications (absence or presence of a signal at a given place). This logical indication was soon associated with a semi-analog data (presence or absence of a signal above an analog threshold, i.e. the discrimination function) as with FILAS, RBA and RBB circuits. The evolution continued with the appearance of analog data capture (time, amplitude, charge) and the corresponding circuits: IFT circuits, analog-to-digital converters [fr

  10. Stimulus repetition and the perception of time: the effects of prior exposure on temporal discrimination, judgment, and production.

    Directory of Open Access Journals (Sweden)

    William J Matthews

    Full Text Available It has been suggested that repeated stimuli have shorter subjective duration than novel items, perhaps because of a reduction in the neural response to repeated presentations of the same object. Five experiments investigated the effects of repetition on time perception and found further evidence that immediate repetition reduces apparent duration, consistent with the idea that subjective duration is partly based on neural coding efficiency. In addition, the experiments found (a no effect of repetition on the precision of temporal discrimination, (b that the effects of repetition disappeared when there was a modest lag between presentations, (c that, across participants, the size of the repetition effect correlated with temporal discrimination, and (d that the effects of repetition suggested by a temporal production task were the opposite of those suggested by temporal judgments. The theoretical and practical implications of these results are discussed.

  11. A Real Time AI Approach to Discrimination Boost Phase Optical Sensor Systems in SDI Architectures

    Science.gov (United States)

    Sloggett, David R.

    1990-04-01

    Interest has been rekindled in the potential utility of Ballistic Missile Defence (BMD) systems 1,2 and their ability to enhance the existing NATO strategic defence posture 3,4. Whereas in the past BMD systems have been thought to be vulnerable to relatively simple offence countermeasures, technological developments that have occurred over the past 20 years offer the potential to solve some of the main criticisms that have bedeviled BMD research since its inception in the early 1950s. One of the key areas where dramatic developments have taken place is in the field of electro-optic sensor technologies where developments in device sensitivity and packing density offer new solutions to threat detection, tracking and discrimination that complement data traditionally associated with radar based systems. Analysis has shown 5 that optical sensor systems can make a significant contribution to threat analysis in the boost and mid course phases of flight of ballistic missile systems. In the Boost phase the large amounts of energy contained within the plume of a ballistic missile system provides a signature that must be detected against cloud and earth backgrounds - necessitating viewing from space. The process of detection is complicated by reflected sunlight and other sources of false alarms. The optical sensor systems must therefore be adaptable and capable of reasoning about the location of the signatures, their persistence and temporal variations. Much of this processing is ideally carried out at the sensor system - in order to eliminate false alarms and reduce the communications bandwidths required to transfer the sensor data to centralised early warning and battle management facilities. In the mid course phase optical sensor systems can be used to detect warm objects against the background of deep space. These sensor systems can form tracks on these objects that can be merged into 3D tracks as data from individual sensor systems are combined. As closely spaced objects

  12. Timing Jitter Analysis for Clock recovery Circuits Based on an Optoelectronic Phase-Locked Loop (OPLL)

    DEFF Research Database (Denmark)

    Zibar, Darko; Mørk, Jesper; Oxenløwe, Leif Katsuo

    2005-01-01

    Timing jitter of an OPLL based clock recovery is investigated. We demonstrate how loop gain, input and VCO signal jitter, loop filter bandwidth and a loop time delay influence jitter of the extracted clock signal......Timing jitter of an OPLL based clock recovery is investigated. We demonstrate how loop gain, input and VCO signal jitter, loop filter bandwidth and a loop time delay influence jitter of the extracted clock signal...

  13. Effects over time of self-reported direct and vicarious racial discrimination on depressive symptoms and loneliness among Australian school students.

    Science.gov (United States)

    Priest, Naomi; Perry, Ryan; Ferdinand, Angeline; Kelaher, Margaret; Paradies, Yin

    2017-02-03

    Racism and racial discrimination are increasingly acknowledged as a critical determinant of health and health inequalities. However, patterns and impacts of racial discrimination among children and adolescents remain under-investigated, including how different experiences of racial discrimination co-occur and influence health and development over time. This study examines associations between self-reported direct and vicarious racial discrimination experiences and loneliness and depressive symptoms over time among Australian school students. Across seven schools, 142 students (54.2% female), age at T1 from 8 to 15 years old (M = 11.14, SD = 2.2), and from diverse racial/ethnic and migration backgrounds (37.3% born in English-speaking countries as were one or both parents) self-reported racial discrimination experiences (direct and vicarious) and mental health (depressive symptoms and loneliness) at baseline and 9 months later at follow up. A full cross-lagged panel design was modelled using MPLUS v.7 with all variables included at both time points. A cross-lagged effect of perceived direct racial discrimination on later depressive symptoms and on later loneliness was found. As expected, the effect of direct discrimination on both health outcomes was unidirectional as mental health did not reciprocally influence reported racism. There was no evidence that vicarious racial discrimination influenced either depressive symptoms or loneliness beyond the effect of direct racial discrimination. Findings suggest direct racial discrimination has a persistent effect on depressive symptoms and loneliness among school students over time. Future work to explore associations between direct and vicarious discrimination is required.

  14. Off-line correction for excessive constant-fraction-discriminator walk in neutron time-of-flight experiments

    International Nuclear Information System (INIS)

    Heilbronn, Lawrence; Iwata, Yoshiyuki; Iwase, H.

    2003-01-01

    A method for reducing excessive constant-fraction-discriminator walk that utilizes experimental data in the off-line analysis stage is introduced. Excessive walk is defined here as any walk that leads to an overall timing resolution that is much greater than the intrinsic timing resolution of the detection system. The method is able to reduce the contribution to the overall timing resolution from the walk that is equal to or less than the intrinsic timing resolution of the detectors. Although the method is explained in the context of a neutron time-of-flight experiment, it is applicable to any data set that satisfies two conditions. (1) A measure of the signal amplitude for each event must be recorded on an event-by-event basis; and (2) There must be a distinguishable class of events present where the timing information is known a priori

  15. Off-line correction for excessive constant-fraction-discriminator walk in neutron time-of-flight experiments

    International Nuclear Information System (INIS)

    Heilbronn, L.; Iwata, Y.; Iwase, H.

    2004-01-01

    A method for reducing excessive constant-fraction-discriminator walk that utilizes experimental data in the off-line analysis stage is introduced. Excessive walk is defined here as any walk that leads to an overall timing resolution that is much greater than the intrinsic timing resolution of the detection system. The method is able to reduce the contribution to the overall timing resolution from the walk to a value that is equal to or less than the intrinsic timing resolution of the detectors. Although the method is explained in the context of a neutron time-of-flight experiment, it is applicable to any data set that satisfies two conditions: (1) a measure of the signal amplitude for each event must be recorded on an event-by-event basis; and (2) there must be a distinguishable class of events present where the timing information is known a priori

  16. Penetrating heavy ion charge and velocity discrimination with a TimePix-based Si detector (for space radiation applications)

    Energy Technology Data Exchange (ETDEWEB)

    Pinsky, Lawrence S., E-mail: pinsky@uh.edu [University of Houston, 4800 Calhoun Blvd., Houston, TX 77204-5005 (United States); Empl, Anton [University of Houston, 4800 Calhoun Blvd., Houston, TX 77204-5005 (United States); Gutierrez, Andrea [University of Montreal, 2905 Chemin des services, Montreal, Que., H3T 1J4 (Canada); Jakubek, Jan [Institute of Experimental and Applied Physics, Czech Technical University, Horska 3a/22, CZ-12800 Prague 2-Albertov (Czech Republic); Kitamura, Hisashi [National Institute for Radiological Sciences, Anagawa 4-9-1, Inage, Chiba 263-8555 (Japan); Miller, Jack [Space Sciences Laboratory, Lawrence Berkeley National Laboratory, 1 Cyclotron Road, Berkeley, CA 94720 (United States); Leroy, Claude [University of Montreal, 2905 Chemin des services, Montreal, Que., H3T 1J4 (Canada); Stoffle, Nicholas [University of Houston, 4800 Calhoun Blvd., Houston, TX 77204-5005 (United States); Pospisil, Stanislav [Institute of Experimental and Applied Physics, Czech Technical University, Horska 3a/22, CZ-12800 Prague 2-Albertov (Czech Republic); Uchihori, Yukio; Yasuda, Nakahiro [National Institute for Radiological Sciences, Anagawa 4-9-1, Inage, Chiba 263-8555 (Japan); Zeitlin, Cary [Southwest Research Institute, 6220 Culebra Rd., San Antonio, TX 78238-5166 (United States)

    2011-05-15

    Exposures were made with Medipix2 TimePix-based Si detectors at the HIMAC facility in Japan to explore the potential for discrimination between tracks with differing charges and energies, but with very similar dE/dx values. Data were taken at 15 deg. increments for a number of different beams including 600 and 800 MeV/A Si, 180 MeV/A Ne and 100 MeV/A O. Data were also obtained for 400 MeV/A Si and 500 MeV/A Fe along with 290 and 180 MeV/A N. The TimePix chips have been calibrated to achieve the maximum resolution. Estimates for the angular resolution for these types of tracks are also possible from these data, which are essential in the development of a TimePix-based dosimetric device for use in a space radiation environment. One of the principal objectives of these data runs was to explore the resolution of TimePix-based Si detectors to discriminate between various ions with different energies and charges, but with similar dE/dx values in Si. Analysis of the images obtained shows the clear differences in the {delta}-ray halos for particles with similar dE/dx values but for differing charges and energies. These measurements are part of an ongoing program to explore the range of capabilities of the TimePix-based detector with respect to dosimetry uses in space.

  17. Inside anesthesia breathing circuits: time to reach a set sevoflurane concentration in toddlers and newborns: simulation using a test lung.

    Science.gov (United States)

    Kern, Delphine; Larcher, Claire; Basset, Bertrand; Alacoque, Xavier; Fesseau, Rose; Samii, Kamran; Minville, Vincent; Fourcade, Olivier

    2012-08-01

    We measured the time it takes to reach the desired inspired anesthetic concentration using the Primus (Drägerwerk, AG, Lübeck, Germany) and the Avance (GE Datex-Ohmeda, Munich, Germany) anesthesia machines with toddler and newborn ventilation settings. The time to reach 95% of inspired target sevoflurane concentration was measured during wash-in from 0 to 6 vol% sevoflurane and during wash-out from 6 to 0 vol% with fresh gas flows equal to 1 and 2 times the minute ventilation. The Avance was faster than the Primus (65 seconds [95% confidence interval (CI): 55 to 78] vs 310 seconds [95% CI: 261 to 359]) at 1.5 L/min fresh gas flow, tidal volume of 50 mL, and 30 breaths/min. Times were shorter by the same magnitude at higher fresh gas flows and higher minute ventilation rates. The effect of doubling fresh gas flow was variable and less than expected. The Primus is slower during newborn than toddler ventilation, whereas the Avance's response time was the same for newborn and toddler ventilation. Our data confirm that the time to reach the target-inspired anesthetic concentration depends on breathing circuit volume, fresh gas flow, and minute ventilation.

  18. Feedback in analog circuits

    CERN Document Server

    Ochoa, Agustin

    2016-01-01

    This book describes a consistent and direct methodology to the analysis and design of analog circuits with particular application to circuits containing feedback. The analysis and design of circuits containing feedback is generally presented by either following a series of examples where each circuit is simplified through the use of insight or experience (someone else’s), or a complete nodal-matrix analysis generating lots of algebra. Neither of these approaches leads to gaining insight into the design process easily. The author develops a systematic approach to circuit analysis, the Driving Point Impedance and Signal Flow Graphs (DPI/SFG) method that does not require a-priori insight to the circuit being considered and results in factored analysis supporting the design function. This approach enables designers to account fully for loading and the bi-directional nature of elements both in the feedback path and in the amplifier itself, properties many times assumed negligible and ignored. Feedback circuits a...

  19. The implementing of high resolution time measuring circuit based on FPGA

    International Nuclear Information System (INIS)

    Zhang Ji; Zeng Yun; Wang Zheng; Li Quiju; Lu Jifang; Wu Jinyuan

    2011-01-01

    It presents the implementing of TDC based on FPGA. The fine timing function part is accomplished through the time interpolators that are composed of the carry chain of intrinsic adders in FPGA. This architecture dates back to the latest technology-WUTDC (Wave Union TDC) that is developed to sub-divide the ultra-wide bins and improve the measure resolution. The board and the online test have been proved that the linearity of converters is satisfying and the time resolution is better than 40 ps. (authors)

  20. Parameter estimation methods for gene circuit modeling from time-series mRNA data: a comparative study

    KAUST Repository

    Fan, M.

    2015-03-29

    Parameter estimation is a challenging computational problemin the reverse engineering of biological systems. Because advances in biotechnology have facilitated wide availability of time-series gene expression data, systematic parameter esti- mation of gene circuitmodels fromsuch time-series mRNA data has become an importantmethod for quantitatively dissecting the regulation of gene expression. By focusing on themodeling of gene circuits, we examine here the perform- ance of three types of state-of-the-art parameter estimation methods: population-basedmethods, onlinemethods and model-decomposition-basedmethods. Our results show that certain population-basedmethods are able to generate high- quality parameter solutions. The performance of thesemethods, however, is heavily dependent on the size of the param- eter search space, and their computational requirements substantially increase as the size of the search space increases. In comparison, onlinemethods andmodel decomposition-basedmethods are computationally faster alternatives and are less dependent on the size of the search space. Among other things, our results show that a hybrid approach that augments computationally fastmethods with local search as a subsequent refinement procedure can substantially increase the qual- ity of their parameter estimates to the level on par with the best solution obtained fromthe population-basedmethods whilemaintaining high computational speed. These suggest that such hybridmethods can be a promising alternative to themore commonly used population-basedmethods for parameter estimation of gene circuit models when limited prior knowledge about the underlying regulatorymechanismsmakes the size of the parameter search space vastly large. © The Author 2015. Published by Oxford University Press.

  1. Finite-time synchronization of Lorenz chaotic systems: theory and circuits

    International Nuclear Information System (INIS)

    Louodop, Patrick; Fotsin, Hilaire; Kountchou, Michaux; Bowong, Samuel

    2013-01-01

    This paper addresses the problem of finite-time master–slave synchronization of Lorenz chaotic systems from a control theoretic point of view. We propose a family of feedback couplings which accomplish the synchronization of Lorenz chaotic systems based on Lyapunov stability theory. These feedback couplings are based on non-periodic functions. A finite horizon can be arbitrarily established by ensuring that chaos synchronization is achieved at established time. An advantage is that some of the proposed feedback couplings are simple and easy to implement. Both mathematical investigations and numerical simulations followed by a Pspice experiment are presented to show the feasibility of the proposed method. (paper)

  2. Dynamic divisive normalization predicts time-varying value coding in decision-related circuits.

    Science.gov (United States)

    Louie, Kenway; LoFaro, Thomas; Webb, Ryan; Glimcher, Paul W

    2014-11-26

    Normalization is a widespread neural computation, mediating divisive gain control in sensory processing and implementing a context-dependent value code in decision-related frontal and parietal cortices. Although decision-making is a dynamic process with complex temporal characteristics, most models of normalization are time-independent and little is known about the dynamic interaction of normalization and choice. Here, we show that a simple differential equation model of normalization explains the characteristic phasic-sustained pattern of cortical decision activity and predicts specific normalization dynamics: value coding during initial transients, time-varying value modulation, and delayed onset of contextual information. Empirically, we observe these predicted dynamics in saccade-related neurons in monkey lateral intraparietal cortex. Furthermore, such models naturally incorporate a time-weighted average of past activity, implementing an intrinsic reference-dependence in value coding. These results suggest that a single network mechanism can explain both transient and sustained decision activity, emphasizing the importance of a dynamic view of normalization in neural coding. Copyright © 2014 the authors 0270-6474/14/3416046-12$15.00/0.

  3. Neutron-gamma discrimination based on pulse shape discrimination in a Ce:LiCaAlF{sub 6} scintillator

    Energy Technology Data Exchange (ETDEWEB)

    Yamazaki, Atsushi, E-mail: a-yamazaki@nucl.nagoya-u.ac.jp [Department of Materials, Physics and Energy Engineering, Graduate School of Engineering, Nagoya University (Japan); Watanabe, Kenichi; Uritani, Akira [Department of Materials, Physics and Energy Engineering, Graduate School of Engineering, Nagoya University (Japan); Iguchi, Tetsuo [Department of Quantum Engineering, Graduate School of Engineering, Nagoya University (Japan); Kawaguchi, Noriaki [Tokuyama Corporation (Japan); Yanagida, Takayuki; Fujimoto, Yutaka; Yokota, Yuui; Kamada, Kei [Institute of Multidisciplinary Research for Advanced Materials (IMRAM), Tohoku University (Japan); Fukuda, Kentaro; Suyama, Toshihisa [Tokuyama Corporation (Japan); Yoshikawa, Akira [Institute of Multidisciplinary Research for Advanced Materials (IMRAM), Tohoku University (Japan); New Industry Creation Hatchery Center (NICHe), Tohoku University (Japan)

    2011-10-01

    We demonstrate neutron-gamma discrimination based on a pulse shape discrimination method in a Ce:LiCAF scintillator. We have tried neutron-gamma discrimination using a difference in the pulse shape or the decay time of the scintillation light pulse. The decay time is converted into the rise time through an integrating circuit. A {sup 252}Cf enclosed in a polyethylene container is used as the source of thermal neutrons and prompt gamma-rays. Obvious separation of neutron and gamma-ray events is achieved using the information of the rise time of the scintillation light pulse. In the separated neutron spectrum, the gamma-ray events are effectively suppressed with little loss of neutron events. The pulse shape discrimination is confirmed to be useful to detect neutrons with the Ce:LiCAF scintillator under an intense high-energy gamma-ray condition.

  4. Wideband continuous-time ΣΔ ADCs, automotive electronics, and power management : advances in analog circuit design 2016

    NARCIS (Netherlands)

    Baschirotto, A.; Harpe, P.J.A.; Makinwa, K.A.A.

    2017-01-01

    This book is based on the 18 tutorials presented during the 25th workshop on Advances in Analog Circuit Design. Expert designers present readers with information about a variety of topics at the frontier of analog circuit design, including low-power and energy-efficient analog electronics, with

  5. Discrimination Between Inrush and Short Circuit Currents in Differential Protection of Power Transformer Based on Correlation Method Using the Wavelet Transform

    OpenAIRE

    M. Rasoulpoor; M. Banejad; A. Ahmadyfard

    2011-01-01

    This paper presents a novel technique for transformer differential protection to prevent incorrect operation due to inrush current. The proposed method in this paper is based on time-frequency transform known as the Wavelet transform. The discrete Wavelet transform is used for analysis the differential current signals in time and frequency domains. The investigation on the energy distribution of the signal on the discrete Wavelet transform components shows the difference distribution between ...

  6. A circuit for detection of interaural time differences in the nucleus laminaris of turtles.

    Science.gov (United States)

    Willis, Katie L; Carr, Catherine E

    2017-11-15

    The physiological hearing range of turtles is approximately 50-1000 Hz, as determined by cochlear microphonics ( Wever and Vernon, 1956a). These low frequencies can constrain sound localization, particularly in red-eared slider turtles, which are freshwater turtles with small heads and isolated middle ears. To determine if these turtles were sensitive to interaural time differences (ITDs), we investigated the connections and physiology of their auditory brainstem nuclei. Tract tracing experiments showed that cranial nerve VIII bifurcated to terminate in the first-order nucleus magnocellularis (NM) and nucleus angularis (NA), and the NM projected bilaterally to the nucleus laminaris (NL). As the NL received inputs from each side, we developed an isolated head preparation to examine responses to binaural auditory stimulation. Magnocellularis and laminaris units responded to frequencies from 100 to 600 Hz, and phase-locked reliably to the auditory stimulus. Responses from the NL were binaural, and sensitive to ITD. Measures of characteristic delay revealed best ITDs around ±200 μs, and NL neurons typically had characteristic phases close to 0, consistent with binaural excitation. Thus, turtles encode ITDs within their physiological range, and their auditory brainstem nuclei have similar connections and cell types to other reptiles. © 2017. Published by The Company of Biologists Ltd.

  7. Design of nuclear pulse shaped circuit based on proportional counter

    International Nuclear Information System (INIS)

    Song Qianqian; Cheng Yi; Tuo Xianguo

    2011-01-01

    Use the self-developed proportional to sample gas tritium in environment and make the measurement. For this detector, a kind of pulse shape circuit based on second order active low pass filtering circuit realized filtering and shaping nuclear pulse by high-speed operational amplifier, with less stages that has been approved for filter Gaussian wave. Use Multisim 10.0 to simulate the different parameters of the filter circuit. The simulation result was consistent with the theoretical results. The experiments proved the feasibility of this circuit, and at the same time provided a convenient and reliable method for analysis and optimization of the nuclear pulse waveform in order for discriminating by MCA. (authors)

  8. Real-time identification of the resistive-wall-mode in DIII-D with Kalman filter ELM discrimination

    International Nuclear Information System (INIS)

    Edgell, D.H.; Fransson, C.M.; Humphreys, D.A.; Ferron, J.R.; Garofalo, A.M.; Kim, J.S.; La Haye, R.J.; Okabayashi, M.; Reimerdes, H.; Strait, E.J.; Turnbull, A.D.

    2004-01-01

    The resistive-wall-mode (RWM) is a major performance-limiting instability in present-day tokamaks. Active control and stabilization of the mode will almost certainly be essential for the success of advanced tokamaks and for the economic viability of tokamak fusion reactors. High performance tokamak plasmas often experience edge-localized-modes (ELMs) which can interfere with RWM identification and control. If the RWM control scheme reacts to an ELM the RWM may be driven unstable instead of controlled. An algorithm for real-time identification of the RWM with discrimination of ELMs in the DIII-D tokamak has been developed using a combination of matched filter and Kalman filter methods. The algorithm has been implemented in DIII-D's real-time plasma control system (PCS) and is available to drive active mode control schemes

  9. Blind Time-Frequency Analysis for Source Discrimination in Multisensor Array Processing

    National Research Council Canada - National Science Library

    Amin, Moeness

    1999-01-01

    .... We have clearly demonstrated, through analysis and simulations, the offerings of time-frequency distributions in solving key problems in sensor array processing, including direction finding, source...

  10. Quality control and authentication of packaged integrated circuits using enhanced-spatial-resolution terahertz time-domain spectroscopy and imaging

    Science.gov (United States)

    Ahi, Kiarash; Shahbazmohamadi, Sina; Asadizanjani, Navid

    2018-05-01

    In this paper, a comprehensive set of techniques for quality control and authentication of packaged integrated circuits (IC) using terahertz (THz) time-domain spectroscopy (TDS) is developed. By material characterization, the presence of unexpected materials in counterfeit components is revealed. Blacktopping layers are detected using THz time-of-flight tomography, and thickness of hidden layers is measured. Sanded and contaminated components are detected by THz reflection-mode imaging. Differences between inside structures of counterfeit and authentic components are revealed through developing THz transmission imaging. For enabling accurate measurement of features by THz transmission imaging, a novel resolution enhancement technique (RET) has been developed. This RET is based on deconvolution of the THz image and the THz point spread function (PSF). The THz PSF is mathematically modeled through incorporating the spectrum of the THz imaging system, the axis of propagation of the beam, and the intensity extinction coefficient of the object into a Gaussian beam distribution. As a result of implementing this RET, the accuracy of the measurements on THz images has been improved from 2.4 mm to 0.1 mm and bond wires as small as 550 μm inside the packaging of the ICs are imaged.

  11. Real-time monitoring system for improving corona electrostatic separation in the process of recovering waste printed circuit boards.

    Science.gov (United States)

    Li, Jia; Zhou, Quan; Xu, Zhenming

    2014-12-01

    Although corona electrostatic separation is successfully used in recycling waste printed circuit boards in industrial applications, there are problems that cannot be resolved completely, such as nonmetal particle aggregation and spark discharge. Both of these problems damage the process of separation and are not easy to identify during the process of separation in industrial applications. This paper provides a systematic study on a real-time monitoring system. Weight monitoring systems were established to continuously monitor the separation process. A Virtual Instrumentation program written by LabVIEW was utilized to sample and analyse the mass increment of the middling product. It includes four modules: historical data storage, steady-state analysis, data computing and alarm. Three kinds of operating conditions were used to verify the applicability of the monitoring system. It was found that the system achieved the goal of monitoring during the separation process and realized the function of real-time analysis of the received data. The system also gave comprehensible feedback on the accidents of material blockages in the feed inlet and high-voltage spark discharge. With the warning function of the alarm system, the whole monitoring system could save the human cost and help the new technology to be more easily applied in industry. © The Author(s) 2014.

  12. Classificaiton and Discrimination of Sources with Time-Varying Frequency and Spatial Spectra

    National Research Council Canada - National Science Library

    Amin, Moeness G; Zhang, Yimin; Wang, Genyuan; Obeidat, Baha; Setlur, Pawan; Estephan, Habib

    2007-01-01

    .... We have introduced the spatial polarimetric time-frequency distributions (SPTFDs) as a platform for processing polarized nonstationary signals incident on multiple dual-polarized double-feed antennas...

  13. Blind Time-Frequency Analysis for Source Discrimination in Multisensor Array Processing

    National Research Council Canada - National Science Library

    Amin, Moeness

    2001-01-01

    .... We pioneered the development of multi-sensor receivers based on quadratic time-frequency and joint-variable distributions, and have provided the theoretical framework for solving direction finding...

  14. The effects of incidentally learned temporal and spatial predictability on response times and visual fixations during target detection and discrimination.

    Directory of Open Access Journals (Sweden)

    Melissa R Beck

    Full Text Available Responses are quicker to predictable stimuli than if the time and place of appearance is uncertain. Studies that manipulate target predictability often involve overt cues to speed up response times. However, less is known about whether individuals will exhibit faster response times when target predictability is embedded within the inter-trial relationships. The current research examined the combined effects of spatial and temporal target predictability on reaction time (RT and allocation of overt attention in a sustained attention task. Participants responded as quickly as possible to stimuli while their RT and eye movements were measured. Target temporal and spatial predictability were manipulated by altering the number of: 1 different time intervals between a response and the next target; and 2 possible spatial locations of the target. The effects of target predictability on target detection (Experiment 1 and target discrimination (Experiment 2 were tested. For both experiments, shorter RTs as target predictability increased across both space and time were found. In addition, the influences of spatial and temporal target predictability on RT and the overt allocation of attention were task dependent; suggesting that effective orienting of attention relies on both spatial and temporal predictability. These results indicate that stimulus predictability can be increased without overt cues and detected purely through inter-trial relationships over the course of repeated stimulus presentations.

  15. A sequential logic circuit for coincidences randomly distributed in 'time' and 'duration', with selection and total sampling

    International Nuclear Information System (INIS)

    Carnet, Bernard; Delhumeau, Michel

    1971-06-01

    The principles of binary analysis applied to the investigation of sequential circuits were used to design a two way coincidence circuit whose input may be, random or periodic variables of constant or variable duration. The output signal strictly reproduces the characteristics of the input signal triggering the coincidence. A coincidence between input signals does not produce any output signal if one of the signals has already triggered the output signal. The characteristics of the output signal in relation to those of the input signal are: minimum time jitter, excellent duration reproducibility and maximum efficiency. Some rules are given for achieving these results. The symmetry, transitivity and non-transitivity characteristics of the edges on the primitive graph are analyzed and lead to some rules for positioning the states on a secondary graph. It is from this graph that the equations of the circuits can be calculated. The development of the circuit and its dynamic testing are discussed. For this testing, the functioning of the circuit is simulated by feeding into the input randomly generated signals

  16. Time and Number Discrimination in a Bisection Task with a Sequence of Stimuli: A Developmental Approach.

    Science.gov (United States)

    Droit-Volet, Sylvie; Clement, Angelique; Fayol, Michel

    2003-01-01

    This study tested 5- and 8-year-olds and adults in a bisection task with a sequence of stimuli in which time and number co-varied. Findings indicated that the number of stimuli interfered with 5-year-olds' performance on the temporal bisection task. Number interference decreased both with age and counting strategy. In the numerical bisection task,…

  17. Neural Mechanisms of Interference Control and Time Discrimination in Attention-Deficit/Hyperactivity Disorder

    Science.gov (United States)

    Vloet, Timo D.; Gilsbach, Susanne; Neufang, Susanne; Fink, Gereon R.; Herpertz-Dahlmann, Beate; Konrad, Kerstin

    2010-01-01

    Objective: Both executive functions and time perception are typically impaired in subjects with attention-deficit/hyperactivity disorder (ADHD). However, the exact neural mechanisms underlying these deficits remain to be investigated. Method: Fourteen subjects with ADHD and 14 age- and IQ-matched controls (aged 9 through 15 years) were assessed…

  18. PANDORA, a large volume low-energy neutron detector with real-time neutron-gamma discrimination

    Science.gov (United States)

    Stuhl, L.; Sasano, M.; Yako, K.; Yasuda, J.; Baba, H.; Ota, S.; Uesaka, T.

    2017-09-01

    The PANDORA (Particle Analyzer Neutron Detector Of Real-time Acquisition) system, which was developed for use in inverse kinematics experiments with unstable isotope beams, is a neutron detector based on a plastic scintillator coupled to a digital readout. PANDORA can be used for any reaction study involving the emission of low energy neutrons (100 keV-10 MeV) where background suppression and an increased signal-to-noise ratio are crucial. The digital readout system provides an opportunity for pulse shape discrimination (PSD) of the detected particles as well as intelligent triggering based on PSD. The figure of merit results of PANDORA are compared to the data in literature. Using PANDORA, 91 ± 1% of all detected neutrons can be separated, while 91 ± 1% of the detected gamma rays can be excluded, reducing the gamma ray background by one order of magnitude.

  19. Real-Time Discrimination and Versatile Profiling of Spontaneous Reactive Oxygen Species in Living Organisms with a Single Fluorescent Probe.

    Science.gov (United States)

    Zhang, Ruilong; Zhao, Jun; Han, Guangmei; Liu, Zhengjie; Liu, Cui; Zhang, Cheng; Liu, Bianhua; Jiang, Changlong; Liu, Renyong; Zhao, Tingting; Han, Ming-Yong; Zhang, Zhongping

    2016-03-23

    Fluorescent probes are powerful tools for the investigations of reactive oxygen species (ROS) in living organisms by visualization and imaging. However, the multiparallel assays of several ROS with multiple probes are often limited by the available number of spectrally nonoverlapping chromophores together with large invasive effects and discrepant biological locations. Meanwhile, the spontaneous ROS profilings in various living organs/tissues are also limited by the penetration capability of probes across different biological barriers and the stability in reactive in vivo environments. Here, we report a single fluorescent probe to achieve the effective discrimination and profiling of hydroxyl radicals (•OH) and hypochlorous acid (HClO) in living organisms. The probe is constructed by chemically grafting an additional five-membered heterocyclic ring and a lateral triethylene glycol chain to a fluorescein mother, which does not only turn off the fluorescence of fluorescein, but also create the dual reactive sites to ROS and the penetration capability in passing through various biological barriers. The reactions of probe with •OH and HClO simultaneously result in cyan and green emissions, respectively, providing the real-time discrimination and quantitative analysis of the two ROS in cellular mitochondria. Surprisingly, the accumulation of probes in the intestine and liver of a normal-state zebrafish and the transfer pathway from intestine-to-blood-to-organ/tissue-to-kidney-to-excretion clearly present the profiling of spontaneous •OH and HClO in these metabolic organs. In particular, the stress generation of •OH at the fresh wound of zebrafish is successfully visualized for the first time, in spite of its extremely short lifetime.

  20. Eye movements discriminate fatigue due to chronotypical factors and time spent on task--a double dissociation.

    Directory of Open Access Journals (Sweden)

    Dario Cazzoli

    Full Text Available Systematic differences in circadian rhythmicity are thought to be a substantial factor determining inter-individual differences in fatigue and cognitive performance. The synchronicity effect (when time of testing coincides with the respective circadian peak period seems to play an important role. Eye movements have been shown to be a reliable indicator of fatigue due to sleep deprivation or time spent on cognitive tasks. However, eye movements have not been used so far to investigate the circadian synchronicity effect and the resulting differences in fatigue. The aim of the present study was to assess how different oculomotor parameters in a free visual exploration task are influenced by: a fatigue due to chronotypical factors (being a 'morning type' or an 'evening type'; b fatigue due to the time spent on task. Eighteen healthy participants performed a free visual exploration task of naturalistic pictures while their eye movements were recorded. The task was performed twice, once at their optimal and once at their non-optimal time of the day. Moreover, participants rated their subjective fatigue. The non-optimal time of the day triggered a significant and stable increase in the mean visual fixation duration during the free visual exploration task for both chronotypes. The increase in the mean visual fixation duration correlated with the difference in subjectively perceived fatigue at optimal and non-optimal times of the day. Conversely, the mean saccadic speed significantly and progressively decreased throughout the duration of the task, but was not influenced by the optimal or non-optimal time of the day for both chronotypes. The results suggest that different oculomotor parameters are discriminative for fatigue due to different sources. A decrease in saccadic speed seems to reflect fatigue due to time spent on task, whereas an increase in mean fixation duration a lack of synchronicity between chronotype and time of the day.

  1. Stochastic formalism-based seafloor feature discrimination using multifractality of time-dependent acoustic backscatter

    Digital Repository Service at National Institute of Oceanography (India)

    Haris, K.; Chakraborty, B.

    Nonlin. Processes Geophys., 21, 101–113, 2014 www.nonlin-processes-geophys.net/21/101/2014/ doi:10.5194/npg-21-101-2014 © Author(s) 2014. CC Attribution 3.0 License. Nonlinear Processes in Geophysics O pen A ccess Stochastic formalism-based seafloor... shifted in time to align with the selected feature (Fig. 2). The aligned echo envelopes were averaged to obtain stable acoustic signals to Nonlin. Processes Geophys., 21, 101–113, 2014 www.nonlin-processes-geophys.net/21/101/2014/ K. Haris and B...

  2. Structural Discrimination

    DEFF Research Database (Denmark)

    Thorsen, Mira Skadegård

    discrimination as two ways of articulating particular, opaque forms of racial discrimination that occur in everyday Danish (and other) contexts, and have therefore become normalized. I present and discuss discrimination as it surfaces in data from my empirical studies of discrimination in Danish contexts...

  3. Discrimination of gastrointestinal nematode eggs from crude fecal egg preparations by inhibitor-resistant conventional and real-time PCR.

    Directory of Open Access Journals (Sweden)

    Janina Demeler

    Full Text Available Diagnosis of gastrointestinal nematodes relies predominantly on coproscopic methods such as flotation, Kato-Katz, McMaster or FLOTAC. Although FLOTAC allows accurate quantification, many nematode eggs can only be differentiated to genus or family level. Several molecular diagnostic tools discriminating closely related species suffer from high costs for DNA isolation from feces and limited sensitivity since most kits use only small amounts of feces (<1 g. A direct PCR from crude egg preparations was designed for full compatibility with FLOTAC to accurately quantify eggs per gram feces (epg and determine species composition. Eggs were recovered from the flotation solution and concentrated by sieving. Lysis was achieved by repeated boiling and freezing cycles - only Trichuris eggs required additional mechanic disruption. Egg lysates were directly used as template for PCR with Phusion DNA polymerase which is particularly resistant to PCR inhibitors. Qualitative results were obtained with feces of goats, cattle, horses, swine, cats, dogs and mice. The finally established protocol was also compatible with quantitative real-time PCR in the presence of EvaGreen and no PCR inhibition was detectable when extracts were diluted at least fourfold. Sensitivity was comparable to DNA isolation protocols and spiked samples with five epg were reliably detected. For Toxocara cati a detection limit below one epg was demonstrated. It was possible to distinguish T. cati and Toxocara canis using high resolution melt (HRM analysis, a rapid tool for species identification. In human samples, restriction fragment length polymorphism (RFLP and HRM analysis were used to discriminate Necator americanus and Ancylostoma duodenale. The method is able to significantly improve molecular diagnosis of gastrointestinal nematodes by increasing speed and sensitivity while decreasing overall costs. For identification of species or resistance alleles, analysis of PCR products with many

  4. Discrimination of gastrointestinal nematode eggs from crude fecal egg preparations by inhibitor-resistant conventional and real-time PCR.

    Science.gov (United States)

    Demeler, Janina; Ramünke, Sabrina; Wolken, Sonja; Ianiello, Davide; Rinaldi, Laura; Gahutu, Jean Bosco; Cringoli, Giuseppe; von Samson-Himmelstjerna, Georg; Krücken, Jürgen

    2013-01-01

    Diagnosis of gastrointestinal nematodes relies predominantly on coproscopic methods such as flotation, Kato-Katz, McMaster or FLOTAC. Although FLOTAC allows accurate quantification, many nematode eggs can only be differentiated to genus or family level. Several molecular diagnostic tools discriminating closely related species suffer from high costs for DNA isolation from feces and limited sensitivity since most kits use only small amounts of feces (PCR from crude egg preparations was designed for full compatibility with FLOTAC to accurately quantify eggs per gram feces (epg) and determine species composition. Eggs were recovered from the flotation solution and concentrated by sieving. Lysis was achieved by repeated boiling and freezing cycles - only Trichuris eggs required additional mechanic disruption. Egg lysates were directly used as template for PCR with Phusion DNA polymerase which is particularly resistant to PCR inhibitors. Qualitative results were obtained with feces of goats, cattle, horses, swine, cats, dogs and mice. The finally established protocol was also compatible with quantitative real-time PCR in the presence of EvaGreen and no PCR inhibition was detectable when extracts were diluted at least fourfold. Sensitivity was comparable to DNA isolation protocols and spiked samples with five epg were reliably detected. For Toxocara cati a detection limit below one epg was demonstrated. It was possible to distinguish T. cati and Toxocara canis using high resolution melt (HRM) analysis, a rapid tool for species identification. In human samples, restriction fragment length polymorphism (RFLP) and HRM analysis were used to discriminate Necator americanus and Ancylostoma duodenale. The method is able to significantly improve molecular diagnosis of gastrointestinal nematodes by increasing speed and sensitivity while decreasing overall costs. For identification of species or resistance alleles, analysis of PCR products with many different post PCR methods can

  5. Different target-discrimination times can be followed by the same saccade-initiation timing in different stimulus conditions during visual searches

    Science.gov (United States)

    Tanaka, Tomohiro; Nishida, Satoshi

    2015-01-01

    The neuronal processes that underlie visual searches can be divided into two stages: target discrimination and saccade preparation/generation. This predicts that the length of time of the prediscrimination stage varies according to the search difficulty across different stimulus conditions, whereas the length of the latter postdiscrimination stage is stimulus invariant. However, recent studies have suggested that the length of the postdiscrimination interval changes with different stimulus conditions. To address whether and how the visual stimulus affects determination of the postdiscrimination interval, we recorded single-neuron activity in the lateral intraparietal area (LIP) when monkeys (Macaca fuscata) performed a color-singleton search involving four stimulus conditions that differed regarding luminance (Bright vs. Dim) and target-distractor color similarity (Easy vs. Difficult). We specifically focused on comparing activities between the Bright-Difficult and Dim-Easy conditions, in which the visual stimuli were considerably different, but the mean reaction times were indistinguishable. This allowed us to examine the neuronal activity when the difference in the degree of search speed between different stimulus conditions was minimal. We found that not only prediscrimination but also postdiscrimination intervals varied across stimulus conditions: the postdiscrimination interval was longer in the Dim-Easy condition than in the Bright-Difficult condition. Further analysis revealed that the postdiscrimination interval might vary with stimulus luminance. A computer simulation using an accumulation-to-threshold model suggested that the luminance-related difference in visual response strength at discrimination time could be the cause of different postdiscrimination intervals. PMID:25995344

  6. Resonance circuits for adiabatic circuits

    Directory of Open Access Journals (Sweden)

    C. Schlachta

    2003-01-01

    Full Text Available One of the possible techniques to reduces the power consumption in digital CMOS circuits is to slow down the charge transport. This slowdown can be achieved by introducing an inductor in the charging path. Additionally, the inductor can act as an energy storage element, conserving the energy that is normally dissipated during discharging. Together with the parasitic capacitances from the circuit a LCresonant circuit is formed.

  7. Effect of time walk in the use of single channel analyzer/discriminator for saturated pulses in the 4πβ–γ coincidence experiments

    International Nuclear Information System (INIS)

    Kawada, Yasushi; Yunoki, Akira; Yamada, Takahiro; Hino, Yoshio

    2016-01-01

    Using the TAC technique, the timing properties of a 4πβ–γ coincidence counting system were experimentally studied with an emphasis on saturated pulses. Experiments were performed for several discriminators (integral mode of TSCA) each with different kinds of timing techniques. Timing spectra were measured at various applied voltage to the 4π proportional detector covering the entire region of the plateau. Most of timing discriminators show good timing property when the pulses remain the linear region, but suddenly deteriorate after the pulses was saturated, and the timing spectra expands seriously up to a few μs in some types of timing discriminator. To overcome this problem, two techniques were proposed. - Highlights: • Timing properties of several kinds of SCA/Discriminators were studied, including trailing edge CFT. • Focus of study on saturated pulses, using a 4πβ–γ coincidence counting system and TAC. • Validity of two novel techniques to overcome this problem was shown.

  8. A pulse amplitude discriminator with very low-power consuming

    International Nuclear Information System (INIS)

    Deng Changming; Liu Zhengshan; Zhang Zhiyong; Cheng Chang

    2000-01-01

    A low-power pulse amplitude discriminator is described. The discriminator circuit is mainly composed of an integrated voltage comparator, MAX921, and owns the characters of very low-power and low operating voltage

  9. Analysis of Bernstein's factorization circuit

    NARCIS (Netherlands)

    Lenstra, A.K.; Shamir, A.; Tomlinson, J.; Tromer, E.; Zheng, Y.

    2002-01-01

    In [1], Bernstein proposed a circuit-based implementation of the matrix step of the number field sieve factorization algorithm. These circuits offer an asymptotic cost reduction under the measure "construction cost x run time". We evaluate the cost of these circuits, in agreement with [1], but argue

  10. Behavioral synthesis of asynchronous circuits

    DEFF Research Database (Denmark)

    Nielsen, Sune Fallgaard

    2005-01-01

    This thesis presents a method for behavioral synthesis of asynchronous circuits, which aims at providing a synthesis flow which uses and tranfers methods from synchronous circuits to asynchronous circuits. We move the synchronous behavioral synthesis abstraction into the asynchronous handshake...... is idle. This reduces unnecessary switching activity in the individual functional units and therefore the energy consumption of the entire circuit. A collection of behavioral synthesis algorithms have been developed allowing the designer to perform time and power constrained design space exploration...

  11. Context effects in a temporal discrimination task" further tests of the Scalar Expectancy Theory and Learning-to-Time models.

    Science.gov (United States)

    Arantes, Joana; Machado, Armando

    2008-07-01

    Pigeons were trained on two temporal bisection tasks, which alternated every two sessions. In the first task, they learned to choose a red key after a 1-s signal and a green key after a 4-s signal; in the second task, they learned to choose a blue key after a 4-s signal and a yellow key after a 16-s signal. Then the pigeons were exposed to a series of test trials in order to contrast two timing models, Learning-to-Time (LeT) and Scalar Expectancy Theory (SET). The models made substantially different predictions particularly for the test trials in which the sample duration ranged from 1 s to 16 s and the choice keys were Green and Blue, the keys associated with the same 4-s samples: LeT predicted that preference for Green should increase with sample duration, a context effect, but SET predicted that preference for Green should not vary with sample duration. The results were consistent with LeT. The present study adds to the literature the finding that the context effect occurs even when the two basic discriminations are never combined in the same session.

  12. Development of an integrated circuit VLSI used for time measurement and selective read out in the front end electronics of the DIRC for the Babar experience at SLAC; Developpement d'un circuit integre VLSI assurant mesure de temps et lecture selective dans l'electronique frontale du compteur DIRC de l'experience babar a slac

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, B

    1999-07-01

    This thesis deals with the design the development and the tests of an integrated circuit VLSI, supplying selective read and time measure for 16 channels. This circuit has been developed for a experiment of particles physics, BABAR, that will take place at SLAC (Stanford Linear Accelerator Center). A first part describes the physical stakes of the experiment, the electronic architecture and the place of the developed circuit in the research program. The second part presents the technical drawings of the circuit, the prototypes leading to the final design and the validity tests. (A.L.B.)

  13. Studying DDT Susceptibility at Discriminating Time Intervals Focusing on Maximum Limit of Exposure Time Survived by DDT Resistant Phlebotomus argentipes (Diptera: Psychodidae): an Investigative Report.

    Science.gov (United States)

    Rama, Aarti; Kesari, Shreekant; Das, Pradeep; Kumar, Vijay

    2017-07-24

    Extensive application of routine insecticide i.e., dichlorodiphenyltrichloroethane (DDT) to control Phlebotomus argentipes (Diptera: Psychodidae), the proven vector of visceral leishmaniasis in India, had evoked the problem of resistance/tolerance against DDT, eventually nullifying the DDT dependent strategies to control this vector. Because tolerating an hour-long exposure to DDT is not challenging enough for the resistant P. argentipes, estimating susceptibility by exposing sand flies to insecticide for just an hour becomes a trivial and futile task.Therefore, this bioassay study was carried out to investigate the maximum limit of exposure time to which DDT resistant P. argentipes can endure the effect of DDT for their survival. The mortality rate of laboratory-reared DDT resistant strain P. argentipes exposed to DDT was studied at discriminating time intervals of 60 min and it was concluded that highly resistant sand flies could withstand up to 420 min of exposure to this insecticide. Additionally, the lethal time for female P. argentipes was observed to be higher than for males suggesting that they are highly resistant to DDT's toxicity. Our results support the monitoring of tolerance limit with respect to time and hence points towards an urgent need to change the World Health Organization's protocol for susceptibility identification in resistant P. argentipes.

  14. Time to enhancement derived from ultrafast breast MRI as a novel parameter to discriminate benign from malignant breast lesions

    International Nuclear Information System (INIS)

    Mus, Roel D.; Borelli, Cristina; Bult, Peter; Weiland, Elisabeth; Karssemeijer, Nico; Barentsz, Jelle O.; Gubern-Mérida, Albert; Platel, Bram; Mann, Ritse M.

    2017-01-01

    Highlights: • New view-sharing sequences (e.g. TWIST) enable ultrafast dynamic breast MRI. • TWIST sequences accurately characterize the inflow of contrast in breast lesions. • TTE evaluation allows breast lesion classification with very high accuracy. • The use of TTE significantly increases the specificity of breast MRI. • TWIST imaging may increase the potential of breast MRI as screening tool. - Abstract: Objectives: To investigate time to enhancement (TTE) as novel dynamic parameter for lesion classification in breast magnetic resonance imaging (MRI). Methods: In this retrospective study, 157 women with 195 enhancing abnormalities (99 malignant and 96 benign) were included. All patients underwent a bi-temporal MRI protocol that included ultrafast time-resolved angiography with stochastic trajectory (TWIST) acquisitions (1.0 × 0.9 × 2.5 mm, temporal resolution 4.32 s), during the inflow of contrast agent. TTE derived from TWIST series and relative enhancement versus time curve type derived from volumetric interpolated breath-hold examination (VIBE) series were assessed and combined with basic morphological information to differentiate benign from malignant lesions. Receiver operating characteristic analysis and kappa statistics were applied. Results: TTE had a significantly better discriminative ability than curve type (p < 0.001 and p = 0.026 for reader 1 and 2, respectively). Including morphology, sensitivity of TWIST and VIBE assessment was equivalent (p = 0.549 and p = 0.344, respectively). Specificity and diagnostic accuracy were significantly higher for TWIST than for VIBE assessment (p < 0.001). Inter-reader agreement in differentiating malignant from benign lesions was almost perfect for TWIST evaluation (κ = 0.86) and substantial for conventional assessment (κ = 0.75). Conclusions: TTE derived from ultrafast TWIST acquisitions is a valuable parameter that allows robust differentiation between malignant and benign breast lesions with high

  15. Time to enhancement derived from ultrafast breast MRI as a novel parameter to discriminate benign from malignant breast lesions

    Energy Technology Data Exchange (ETDEWEB)

    Mus, Roel D., E-mail: aroel.mus@radboudumc.nl [Department of Radiology, Radboud University Medical Center, Geert Grooteplein Zuid 10, 6525GA Nijmegen (Netherlands); Borelli, Cristina, E-mail: cristinaborelli@hotmail.it [Department of Radiology, Scientific Institute “Casa Sollievo della Sofferenza” Hospital, Viale Cappuccini 1, 71013, San Giovanni Rotondo, Foggia (Italy); Department of Radiology, Radboud University Medical Center (internal address 766), Geert Grooteplein Zuid 10, 6525GA Nijmegen (Netherlands); Bult, Peter, E-mail: peter.bult@radboudumc.nl [Department of Pathology, Radboud University Medical Center, Geert Grooteplein Zuid 10, 6525GA Nijmegen (Netherlands); Weiland, Elisabeth, E-mail: elisabeth.weiland@siemens.com [Siemens Healthcare, Erlangen (Germany); Karssemeijer, Nico, E-mail: nico.karssemeijer@radboudumc.nl [Department of Radiology, Radboud University Medical Center, Geert Grooteplein Zuid 10, 6525GA Nijmegen (Netherlands); Barentsz, Jelle O., E-mail: jelle.barentsz@radboudumc.nl [Department of Radiology, Radboud University Medical Center, Geert Grooteplein Zuid 10, 6525GA Nijmegen (Netherlands); Gubern-Mérida, Albert, E-mail: albert.gubernmerida@radboudumc.nl [Department of Radiology, Radboud University Medical Center, Geert Grooteplein Zuid 10, 6525GA Nijmegen (Netherlands); Platel, Bram, E-mail: bram.platel@radboudumc.nl [Department of Radiology, Radboud University Medical Center, Geert Grooteplein Zuid 10, 6525GA Nijmegen (Netherlands); Mann, Ritse M., E-mail: ritse.mann@radboudumc.nl [Department of Radiology, Radboud University Medical Center, Geert Grooteplein Zuid 10, 6525GA Nijmegen (Netherlands)

    2017-04-15

    Highlights: • New view-sharing sequences (e.g. TWIST) enable ultrafast dynamic breast MRI. • TWIST sequences accurately characterize the inflow of contrast in breast lesions. • TTE evaluation allows breast lesion classification with very high accuracy. • The use of TTE significantly increases the specificity of breast MRI. • TWIST imaging may increase the potential of breast MRI as screening tool. - Abstract: Objectives: To investigate time to enhancement (TTE) as novel dynamic parameter for lesion classification in breast magnetic resonance imaging (MRI). Methods: In this retrospective study, 157 women with 195 enhancing abnormalities (99 malignant and 96 benign) were included. All patients underwent a bi-temporal MRI protocol that included ultrafast time-resolved angiography with stochastic trajectory (TWIST) acquisitions (1.0 × 0.9 × 2.5 mm, temporal resolution 4.32 s), during the inflow of contrast agent. TTE derived from TWIST series and relative enhancement versus time curve type derived from volumetric interpolated breath-hold examination (VIBE) series were assessed and combined with basic morphological information to differentiate benign from malignant lesions. Receiver operating characteristic analysis and kappa statistics were applied. Results: TTE had a significantly better discriminative ability than curve type (p < 0.001 and p = 0.026 for reader 1 and 2, respectively). Including morphology, sensitivity of TWIST and VIBE assessment was equivalent (p = 0.549 and p = 0.344, respectively). Specificity and diagnostic accuracy were significantly higher for TWIST than for VIBE assessment (p < 0.001). Inter-reader agreement in differentiating malignant from benign lesions was almost perfect for TWIST evaluation (κ = 0.86) and substantial for conventional assessment (κ = 0.75). Conclusions: TTE derived from ultrafast TWIST acquisitions is a valuable parameter that allows robust differentiation between malignant and benign breast lesions with high

  16. Seven novel probe systems for real-time PCR provide absolute single-base discrimination, higher signaling, and generic components.

    Science.gov (United States)

    Murray, James L; Hu, Peixu; Shafer, David A

    2014-11-01

    We have developed novel probe systems for real-time PCR that provide higher specificity, greater sensitivity, and lower cost relative to dual-labeled probes. The seven DNA Detection Switch (DDS)-probe systems reported here employ two interacting polynucleotide components: a fluorescently labeled probe and a quencher antiprobe. High-fidelity detection is achieved with three DDS designs: two internal probes (internal DDS and Flip probes) and a primer probe (ZIPR probe), wherein each probe is combined with a carefully engineered, slightly mismatched, error-checking antiprobe. The antiprobe blocks off-target detection over a wide range of temperatures and facilitates multiplexing. Other designs (Universal probe, Half-Universal probe, and MacMan probe) use generic components that enable low-cost detection. Finally, single-molecule G-Force probes employ guanine-mediated fluorescent quenching by forming a hairpin between adjacent C-rich and G-rich sequences. Examples provided show how these probe technologies discriminate drug-resistant Mycobacterium tuberculosis mutants, Escherichia coli O157:H7, oncogenic EGFR deletion mutations, hepatitis B virus, influenza A/B strains, and single-nucleotide polymorphisms in the human VKORC1 gene. Copyright © 2014 American Society for Investigative Pathology and the Association for Molecular Pathology. Published by Elsevier Inc. All rights reserved.

  17. Low-frequency electromagnetic measurements as a zero-time discriminant of nuclear and chemical explosions - OSI research final report

    International Nuclear Information System (INIS)

    Sweeney, J.J.

    1996-12-01

    This is the final report on a series of investigations of low frequency (1-40 Hz) electromagnetic signals produced by above ground and underground chemical explosions and their use for confidence building under the Comprehensive Test-Ban Treaty. I conclude that low frequency electromagnetic measurements can be a very powerful tool for zero-time discrimination of chemical and nuclear explosions for yields of 1 Kt or greater, provided that sensors can be placed within 1-2 km of the suspected detonation point in a tamper-proof, low noise environment. The report includes descriptions and analyses of low frequency electromagnetic measurements associated with chemical explosions carried out in a variety of settings (shallow borehole, open pit mining, underground mining). I examine cavity pressure data from the Non-Proliferation Experiment (underground chemical explosion) and present the hypothesis that electromagnetic signals produced by underground chemical explosions could be produced during rock fracturing. I also review low frequency electromagnetic data from underground nuclear explosions acquired by Lawrence Livermore National Laboratory during the late 1980s. (author)

  18. Acute neuroinflammation impairs context discrimination memory and disrupts pattern separation processes in hippocampus.

    Science.gov (United States)

    Czerniawski, Jennifer; Guzowski, John F

    2014-09-10

    Although it is known that immune system activation can impair cognition, no study to date has linked cognitive deficits during acute neuroinflammation to dysregulation of task-relevant neuronal ensemble activity. Here, we assessed both neural circuit activity and context discrimination memory retrieval, in a within-subjects design, of male rats given systemic administration of saline or lipopolysaccharide (LPS). Rats were exposed over several days to two similar contexts: one of which was paired with weak foot shock and the other was not. After reaching criteria for discriminative freezing, rats were given systemic LPS or saline injection and tested for retrieval of context discrimination 6 h later. Importantly, LPS administration produced an acute neuroinflammatory response in dorsal hippocampus at this time (as assessed by elevation of proinflammatory cytokine mRNA levels) and abolished retrieval of the previously acquired discrimination. The impact of neuroinflammation on hippocampal CA3 and CA1 neural circuit activity was assessed using the Arc/Homer1a cellular analysis of temporal activity by fluorescence in situ hybridization imaging method. Whereas the saline-treated subjects discriminated and had low overlap of hippocampal ensembles activated in the two contexts, LPS-treated subjects did not discriminate and had greater ensemble overlap (i.e., reduced orthogonalization). Additionally, retrieval of standard contextual fear conditioning, which does not require context discrimination, was not affected by pretesting LPS administration. Together, the behavioral and circuit analyses data provide compelling evidence that LPS administration impairs context discrimination memory by disrupting cellular pattern separation processes within the hippocampus, thus linking acute neuroinflammation to disruption of specific neural circuit functions and cognitive impairment. Copyright © 2014 the authors 0270-6474/14/3412470-11$15.00/0.

  19. Changes to the shuttle circuits

    CERN Multimedia

    GS Department

    2011-01-01

    To fit with passengers expectation, there will be some changes to the shuttle circuits as from Monday 10 October. See details on http://cern.ch/ShuttleService (on line on 7 October). Circuit No. 5 is cancelled as circuit No. 1 also stops at Bldg. 33. In order to guarantee shorter travel times, circuit No. 1 will circulate on Meyrin site only and circuit No. 2, with departures from Bldg. 33 and 500, on Prévessin site only. Site Services Section

  20. Interrogating the Spatiotemporal Landscape of Neuromodulatory GPCR Signaling by Real-Time Imaging of cAMP in Intact Neurons and Circuits

    Directory of Open Access Journals (Sweden)

    Brian S. Muntean

    2018-01-01

    Full Text Available Summary: Modulation of neuronal circuits is key to information processing in the brain. The majority of neuromodulators exert their effects by activating G-protein-coupled receptors (GPCRs that control the production of second messengers directly impacting cellular physiology. How numerous GPCRs integrate neuromodulatory inputs while accommodating diversity of incoming signals is poorly understood. In this study, we develop an in vivo tool and analytical suite for analyzing GPCR responses by monitoring the dynamics of a key second messenger, cyclic AMP (cAMP, with excellent quantitative and spatiotemporal resolution in various neurons. Using this imaging approach in combination with CRISPR/Cas9 editing and optogenetics, we interrogate neuromodulatory mechanisms of defined populations of neurons in an intact mesolimbic reward circuit and describe how individual inputs generate discrete second-messenger signatures in a cell- and receptor-specific fashion. This offers a resource for studying native neuronal GPCR signaling in real time. : Muntean et al. develop an in vivo reagent to study processing of neurotransmitter GPCR signals by monitoring real-time dynamics of cAMP responses. They demonstrate application of this approach, in combination with CRISPR/Cas9 gene editing and optogenetics, to interrogate the functional organization of a striatal circuit. Keywords: cAMP, GPCR, neuromodulation, dopamine, striatum, imaging, optogenetics

  1. The time-course of activation in the dorsal and ventral visual streams during landmark cueing and perceptual discrimination tasks.

    Science.gov (United States)

    Lambert, Anthony J; Wootton, Adrienne

    2017-08-01

    Different patterns of high density EEG activity were elicited by the same peripheral stimuli, in the context of Landmark Cueing and Perceptual Discrimination tasks. The C1 component of the visual event-related potential (ERP) at parietal - occipital electrode sites was larger in the Landmark Cueing task, and source localisation suggested greater activation in the superior parietal lobule (SPL) in this task, compared to the Perceptual Discrimination task, indicating stronger early recruitment of the dorsal visual stream. In the Perceptual Discrimination task, source localisation suggested widespread activation of the inferior temporal gyrus (ITG) and fusiform gyrus (FFG), structures associated with the ventral visual stream, during the early phase of the P1 ERP component. Moreover, during a later epoch (171-270ms after stimulus onset) increased temporal-occipital negativity, and stronger recruitment of ITG and FFG were observed in the Perceptual Discrimination task. These findings illuminate the contrasting functions of the dorsal and ventral visual streams, to support rapid shifts of attention in response to contextual landmarks, and conscious discrimination, respectively. Copyright © 2017 Elsevier Ltd. All rights reserved.

  2. Application of the pulse-rise-time discriminator for background noise decreasing in proportional x-ray counters

    International Nuclear Information System (INIS)

    Goganov, D.A.; Guslina, A.G.; Korolev, V.F.; Lozinskij, B.S.; Sklyankin, V.A.

    1977-01-01

    The intrinsic background of commercial rising edge discriminator - based proportional counters has been measured. The block-diagram of the experimental apparatus comprises the detector to be tested, a charge-sensitive amplifier with an amplitude analyzer, a rising edge discriminator (RED) and a scaling device. The rising edges have been analyzed in the range between 0.2 to 0.7 of the pulse amplitude. The RED threshold has been preset to cut off all the edges longer than those of 55 Fe (to register 87% of the 55 Fe quanta). It has been found that by limiting the amplitude discriminator window to +-20% and using a RED the background of commercial counters can be reduced by about an order

  3. Integrated coherent matter wave circuits

    International Nuclear Information System (INIS)

    Ryu, C.; Boshier, M. G.

    2015-01-01

    An integrated coherent matter wave circuit is a single device, analogous to an integrated optical circuit, in which coherent de Broglie waves are created and then launched into waveguides where they can be switched, divided, recombined, and detected as they propagate. Applications of such circuits include guided atom interferometers, atomtronic circuits, and precisely controlled delivery of atoms. We report experiments demonstrating integrated circuits for guided coherent matter waves. The circuit elements are created with the painted potential technique, a form of time-averaged optical dipole potential in which a rapidly moving, tightly focused laser beam exerts forces on atoms through their electric polarizability. Moreover, the source of coherent matter waves is a Bose-Einstein condensate (BEC). Finally, we launch BECs into painted waveguides that guide them around bends and form switches, phase coherent beamsplitters, and closed circuits. These are the basic elements that are needed to engineer arbitrarily complex matter wave circuitry

  4. NINO an ultrafast low-power front-end amplifier discriminator for the time-of-flight detector in the ALICE experiment

    CERN Document Server

    Anghinolfi, F; Krummenacher, F; Usenko, E; Williams, M C S

    2004-01-01

    An ultrafast front-end preamplifier-discriminator chip called NINO has been developed for use in the ALICE time-of-flight detector. The chip has eight channels. Each channel is designed with an amplifier with less than 1-ns peaking time, a discriminator with a minimum detection threshold of 10 fC and an output stage. The output pulse has minimum time jitter (less than 25 ps) on the front edge, and the pulsewidth is dependent of the input signal charge. Each channel consumes 27 mW, and the eight channels fit in a 2*4 mm/sup 2/ ASIC processed in IBM 0.25- mu m CMOS technology. (3 refs).

  5. NINO, an ultra-fast, low-power, front-end amplifier discriminator for the Time-Of-Flight detector in ALICE experiment

    CERN Document Server

    Anghinolfi, F; Krummenacher, F; Usenko, E; Williams, M C S

    2004-01-01

    An ultra fast front-end preamplifier-discriminator chip NINO has been developed for use in the ALICE Time-Of-Flight detector. The chip has 8 channels. Each channel is designed with an amplifier with less than 1 ns peaking time, a discriminator with a minimum detection threshold of 10fC and an output stage. The output pulse has minimum time jitter (less than 25ps) on the front edge, and the pulse width is dependent of the input signal charge. Each channel consumes 27mW, and the 8 channels fit in a 2*4mm/sup 2/ ASIC processed in IBM 0.2 mu m CMOS technology. (3 refs).

  6. Optically controllable molecular logic circuits

    International Nuclear Information System (INIS)

    Nishimura, Takahiro; Fujii, Ryo; Ogura, Yusuke; Tanida, Jun

    2015-01-01

    Molecular logic circuits represent a promising technology for observation and manipulation of biological systems at the molecular level. However, the implementation of molecular logic circuits for temporal and programmable operation remains challenging. In this paper, we demonstrate an optically controllable logic circuit that uses fluorescence resonance energy transfer (FRET) for signaling. The FRET-based signaling process is modulated by both molecular and optical inputs. Based on the distance dependence of FRET, the FRET pathways required to execute molecular logic operations are formed on a DNA nanostructure as a circuit based on its molecular inputs. In addition, the FRET pathways on the DNA nanostructure are controlled optically, using photoswitching fluorescent molecules to instruct the execution of the desired operation and the related timings. The behavior of the circuit can thus be controlled using external optical signals. As an example, a molecular logic circuit capable of executing two different logic operations was studied. The circuit contains functional DNAs and a DNA scaffold to construct two FRET routes for executing Input 1 AND Input 2 and Input 1 AND NOT Input 3 operations on molecular inputs. The circuit produced the correct outputs with all possible combinations of the inputs by following the light signals. Moreover, the operation execution timings were controlled based on light irradiation and the circuit responded to time-dependent inputs. The experimental results demonstrate that the circuit changes the output for the required operations following the input of temporal light signals

  7. Circuit class therapy and 7-day-week therapy increase physiotherapy time, but not patient activity: early results from the CIRCIT trial.

    Science.gov (United States)

    English, Coralie; Bernhardt, Julie; Hillier, Susan

    2014-10-01

    The optimum model of physiotherapy service delivery for maximizing active task practice during rehabilitation after stroke is unknown. The purpose of the study was to examine the relative effectiveness of 2 alternative models of physiotherapy service delivery against a usual care control with regard to increasing patient activity. Substudy within a large 3-armed randomized controlled trial, which compared 3 different models of physiotherapy service delivery, was provided for 4 weeks during subacute, inpatient rehabilitation (n=283). The duration of all physiotherapy sessions was recorded. In addition, 32 participants were observed at 10-minute intervals for 1 weekday and 1 weekend day between 8:00 am and 4:30 pm. At each observation, we recorded physical activity, location, and people present. Participants receiving 7-day-week and circuit class therapy received an additional 3 hours and 22 hours of physiotherapy time, respectively, when compared with usual care. Participants were standing or walking for a median of 8.2% of observations. On weekdays, circuit class therapy participants spent more time in therapy-related activity (10.2% of observations) when compared with usual care participants (6.1% of observations). On weekends, 7-day therapy participants spent more time in therapy-related activity (4.2% of observations) when compared with both usual care and circuit class therapy participants (0% of observations for both groups). Activity levels outside of therapy sessions did not differ between groups. A greater dosage of physiotherapy time did not translate into meaningful increases in physical activity across the day. http://www.anzctr.org.au/. Unique identifier: ACTRN12610000096055. © 2014 American Heart Association, Inc.

  8. A current-excited triple-time-voltage oversampling method for bio-impedance model for cost-efficient circuit system.

    Science.gov (United States)

    Yan Hong; Yong Wang; Wang Ling Goh; Yuan Gao; Lei Yao

    2015-08-01

    This paper presents a mathematic method and a cost-efficient circuit to measure the value of each component of the bio-impedance model at electrode-electrolyte interface. The proposed current excited triple-time-voltage oversampling (TTVO) method deduces the component values by solving triple simultaneous electric equation (TSEE) at different time nodes during a current excitation, which are the voltage functions of time. The proposed triple simultaneous electric equations (TSEEs) allows random selections of the time nodes, hence numerous solutions can be obtained during a single current excitation. Following that, the oversampling approach is engaged by averaging all solutions of multiple TSEEs acquired after a single current excitation, which increases the practical measurement accuracy through the improvement of the signal-to-noise ratio (SNR). In addition, a print circuit board (PCB) that consists a switched current exciter and an analog-to-digital converter (ADC) is designed for signal acquisition. This presents a great cost reduction when compared against other instrument-based measurement data reported [1]. Through testing, the measured values of this work is proven to be in superb agreements on the true component values of the electrode-electrolyte interface model. This work is most suited and also useful for biological and biomedical applications, to perform tasks such as stimulations, recordings, impedance characterizations, etc.

  9. Controllable circuit

    DEFF Research Database (Denmark)

    2010-01-01

    A switch-mode power circuit comprises a controllable element and a control unit. The controllable element is configured to control a current in response to a control signal supplied to the controllable element. The control unit is connected to the controllable element and provides the control...

  10. Circuit Training.

    Science.gov (United States)

    Nelson, Jane B.

    1998-01-01

    Describes a research-based activity for high school physics students in which they build an LC circuit and find its resonant frequency of oscillation using an oscilloscope. Includes a diagram of the apparatus and an explanation of the procedures. (DDR)

  11. Multiplex real-time PCR (TaqMan) assay for the simultaneous detection and discrimination of potato powdery and common scab diseases and pathogens.

    Science.gov (United States)

    Qu, X S; Wanner, L A; Christ, B J

    2011-03-01

    To develop a multiplex real-time PCR assay using TaqMan probes for the simultaneous detection and discrimination of potato powdery scab and common scab, two potato tuber diseases with similar symptoms, and the causal pathogens Spongospora subterranea and plant pathogenic Streptomyces spp. Real-time PCR primers and a probe for S. subterranea were designed based on the DNA sequence of the ribosomal RNA ITS2 region. Primers and a probe for pathogenic Streptomyces were designed based on the DNA sequence of the txtAB genes. The two sets of primer pairs and probes were used in a single real-time PCR assay. The multiplex real-time PCR assay was confirmed to be specific for S. subterranea and pathogenic Streptomyces. The assay detected DNA quantities of 100 fg for each of the two pathogens and linear responses and high correlation coefficients between the amount of DNA and C(t) values for each pathogen were achieved. The presence of two sets of primer pairs and probes and of plant extracts did not alter the sensitivity and efficiency of multiplex PCR amplification. Using the PCR assay, we could discriminate between powdery scab and common scab tubers with similar symptoms. Common scab and powdery scab were detected in some tubers with no visible symptoms. Mixed infections of common scab and powdery scab on single tubers were also revealed. This multiplex real-time PCR assay is a rapid, cost efficient, specific and sensitive tool for the simultaneous detection and discrimination of the two pathogens on infected potato tubers when visual symptoms are inconclusive or not present. Accurate and quick identification and discrimination of the cause of scab diseases on potatoes will provide critical information to potato growers and researchers for disease management. This is important because management strategies for common and powdery scab diseases are very different. © 2011 The Authors. Journal of Applied Microbiology © 2011 The Society for Applied Microbiology.

  12. Radiation-sensitive switching circuits

    Energy Technology Data Exchange (ETDEWEB)

    Moore, J.H.; Cockshott, C.P.

    1976-03-16

    A radiation-sensitive switching circuit has a light emitting diode which supplies light to a photo-transistor, the light being interrupted from time to time. When the photo-transistor is illuminated, current builds up and when this current reaches a predetermined value, a trigger circuit changes state. The peak output of the photo-transistor is measured and the trigger circuit is arranged to change state when the output of the device is a set proportion of the peak output, so as to allow for aging of the components. The circuit is designed to control the ignition system in an automobile engine.

  13. Automatic sweep circuit

    International Nuclear Information System (INIS)

    Keefe, D.J.

    1980-01-01

    An automatically sweeping circuit for searching for an evoked response in an output signal in time with respect to a trigger input is described. Digital counters are used to activate a detector at precise intervals, and monitoring is repeated for statistical accuracy. If the response is not found then a different time window is examined until the signal is found

  14. Automatic sweep circuit

    Science.gov (United States)

    Keefe, Donald J.

    1980-01-01

    An automatically sweeping circuit for searching for an evoked response in an output signal in time with respect to a trigger input. Digital counters are used to activate a detector at precise intervals, and monitoring is repeated for statistical accuracy. If the response is not found then a different time window is examined until the signal is found.

  15. A rapid, simple method for the genetic discrimination of intact Arabidopsis thaliana mutant seeds using metabolic profiling by direct analysis in real-time mass spectrometry

    Directory of Open Access Journals (Sweden)

    Jang Young

    2011-06-01

    Full Text Available Abstract Background Efficient high throughput screening systems of useful mutants are prerequisite for study of plant functional genomics and lots of application fields. Advance in such screening tools, thanks to the development of analytic instruments. Direct analysis in real-time (DART-mass spectrometry (MS by ionization of complex materials at atmospheric pressure is a rapid, simple, high-resolution analytical technique. Here we describe a rapid, simple method for the genetic discrimination of intact Arabidopsis thaliana mutant seeds using metabolic profiling by DART-MS. Results To determine whether this DART-MS combined by multivariate analysis can perform genetic discrimination based on global metabolic profiling, intact Arabidopsis thaliana mutant seeds were subjected to DART-MS without any sample preparation. Partial least squares-discriminant analysis (PLS-DA of DART-MS spectral data from intact seeds classified 14 different lines of seeds into two distinct groups: Columbia (Col-0 and Landsberg erecta (Ler ecotype backgrounds. A hierarchical dendrogram based on partial least squares-discriminant analysis (PLS-DA subdivided the Col-0 ecotype into two groups: mutant lines harboring defects in the phenylpropanoid biosynthetic pathway and mutants without these defects. These results indicated that metabolic profiling with DART-MS could discriminate intact Arabidopsis seeds at least ecotype level and metabolic pathway level within same ecotype. Conclusion The described DART-MS combined by multivariate analysis allows for rapid screening and metabolic characterization of lots of Arabidopsis mutant seeds without complex metabolic preparation steps. Moreover, potential novel metabolic markers can be detected and used to clarify the genetic relationship between Arabidopsis cultivars. Furthermore this technique can be applied to predict the novel gene function of metabolic mutants regardless of morphological phenotypes.

  16. Training on Movement Figure-Ground Discrimination Remediates Low-Level Visual Timing Deficits in the Dorsal Stream, Improving High-Level Cognitive Functioning, Including Attention, Reading Fluency, and Working Memory

    OpenAIRE

    Lawton, Teri; Shelley-Tremblay, John

    2017-01-01

    The purpose of this study was to determine whether neurotraining to discriminate a moving test pattern relative to a stationary background, figure-ground discrimination, improves vision and cognitive functioning in dyslexics, as well as typically-developing normal students. We predict that improving the speed and sensitivity of figure-ground movement discrimination (PATH to Reading neurotraining) acts to remediate visual timing deficits in the dorsal stream, thereby improving processing speed...

  17. Spatial discrimination and visual discrimination

    DEFF Research Database (Denmark)

    Haagensen, Annika M. J.; Grand, Nanna; Klastrup, Signe

    2013-01-01

    Two methods investigating learning and memory in juvenile Gottingen minipigs were evaluated for potential use in preclinical toxicity testing. Twelve minipigs were tested using a spatial hole-board discrimination test including a learning phase and two memory phases. Five minipigs were tested...... in a visual discrimination test. The juvenile minipigs were able to learn the spatial hole-board discrimination test and showed improved working and reference memory during the learning phase. Performance in the memory phases was affected by the retention intervals, but the minipigs were able to remember...... the concept of the test in both memory phases. Working memory and reference memory were significantly improved in the last trials of the memory phases. In the visual discrimination test, the minipigs learned to discriminate between the three figures presented to them within 9-14 sessions. For the memory test...

  18. The use of real-time polymerase chain reaction with high resolution melting (real-time PCR-HRM) analysis for the detection and discrimination of nematodes Bursaphelenchus xylophilus and Bursaphelenchus mucronatus.

    Science.gov (United States)

    Filipiak, Anna; Hasiów-Jaroszewska, Beata

    2016-04-01

    The real-time PCR-HRM analysis was developed for the detection and discrimination of the quarantine nematode Bursaphelenchus xylophilus and Bursaphelenchus mucronatus. A set of primers was designed to target the ITS region of rDNA. The results have demonstrated that this analysis is a valuable tool for differentiation of these both species. Copyright © 2016 Elsevier Ltd. All rights reserved.

  19. The time-walk of analog constant fraction discriminators using very fast scintillator detectors with linear and non-linear energy response

    Energy Technology Data Exchange (ETDEWEB)

    Regis, J.-M., E-mail: regis@ikp.uni-koeln.de [Institut fuer Kernphysik der Universitaet zu Koeln, Zuelpicher Str. 77, 50937 Koeln (Germany); Rudigier, M.; Jolie, J.; Blazhev, A.; Fransen, C.; Pascovici, G.; Warr, N. [Institut fuer Kernphysik der Universitaet zu Koeln, Zuelpicher Str. 77, 50937 Koeln (Germany)

    2012-08-21

    The electronic {gamma}-{gamma} fast timing technique allows for direct nuclear lifetime determination down to the few picoseconds region by measuring the time difference between two coincident {gamma}-ray transitions. Using high resolution ultra-fast LaBr{sub 3}(Ce) scintillator detectors in combination with the recently developed mirror symmetric centroid difference method, nuclear lifetimes are measured with a time resolving power of around 5 ps. The essence of the method is to calibrate the energy dependent position (centroid) of the prompt response function of the setup which is obtained for simultaneously occurring events. This time-walk of the prompt response function induced by the analog constant fraction discriminator has been determined by systematic measurements using different photomultiplier tubes and timing adjustments of the constant fraction discriminator. We propose a universal calibration function which describes the time-walk or the combined {gamma}-{gamma} time-walk characteristics, respectively, for either a linear or a non-linear amplitude versus energy dependency of the scintillator detector output pulses.

  20. Four-junction superconducting circuit

    Science.gov (United States)

    Qiu, Yueyin; Xiong, Wei; He, Xiao-Ling; Li, Tie-Fu; You, J. Q.

    2016-01-01

    We develop a theory for the quantum circuit consisting of a superconducting loop interrupted by four Josephson junctions and pierced by a magnetic flux (either static or time-dependent). In addition to the similarity with the typical three-junction flux qubit in the double-well regime, we demonstrate the difference of the four-junction circuit from its three-junction analogue, including its advantages over the latter. Moreover, the four-junction circuit in the single-well regime is also investigated. Our theory provides a tool to explore the physical properties of this four-junction superconducting circuit. PMID:27356619

  1. Fighting discrimination.

    Science.gov (United States)

    Wientjens, Wim; Cairns, Douglas

    2012-10-01

    In the fight against discrimination, the IDF launched the first ever International Charter of Rights and Responsibilities of People with Diabetes in 2011: a balance between rights and duties to optimize health and quality of life, to enable as normal a life as possible and to reduce/eliminate the barriers which deny realization of full potential as members of society. It is extremely frustrating to suffer blanket bans and many examples exist, including insurance, driving licenses, getting a job, keeping a job and family affairs. In this article, an example is given of how pilots with insulin treated diabetes are allowed to fly by taking the responsibility of using special blood glucose monitoring protocols. At this time the systems in the countries allowing flying for pilots with insulin treated diabetes are applauded, particularly the USA for private flying, and Canada for commercial flying. Encouraging developments may be underway in the UK for commercial flying and, if this materializes, could be used as an example for other aviation authorities to help adopt similar protocols. However, new restrictions implemented by the new European Aviation Authority take existing privileges away for National Private Pilot Licence holders with insulin treated diabetes in the UK. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

  2. Mass discrimination

    Energy Technology Data Exchange (ETDEWEB)

    Broeckman, A. [Rijksuniversiteit Utrecht (Netherlands)

    1978-12-15

    In thermal ionization mass spectrometry the phenomenon of mass discrimination has led to the use of a correction factor for isotope ratio-measurements. The correction factor is defined as the measured ratio divided by the true or accepted value of this ratio. In fact this factor corrects for systematic errors of the whole procedure; however mass discrimination is often associated just with the mass spectrometer.

  3. Contribution to the study of time-resolution in pulse electronics for nuclear physics: phase control circuits; Contribution a l'etude de la resolution en temps de l'electronique impulsionnelle pour physique nucleaire: les circuits de mise en phase

    Energy Technology Data Exchange (ETDEWEB)

    Cortet, J P [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1969-07-01

    Phase control circuits make it possible to improve quite markedly the time resolution in pulse electronics. They replace a random pulse, of which the time of arrival with respect to a reference zero is being measured, by another pulse whose phase is well determined with respect to that, of a clock taken as reference. The time spectrum of the output, delayed, can always be situated inside channels of width {delta}T defined by the clock. The time statistics of the events analyzed is always correct even if the transition time for the circuits defining the channels represents a large fraction of {delta}T: the coding of the time becomes perfect, The phase control circuits, used in precision chronometry, are widely applied in Nuclear Physics since the lime spectra obtained are representative, indirectly, of certain values which are required to be measured with great accuracy. A description is given of: the constitution and operation of phase control circuits; a chain with automatic analysis and automatic reading, built for testing these circuits. Finally the measurement results are given. (author) [French] Les circuits de mise en phase permettent d'ameliorer notablement la resolution en temps de l'electronique impulsionnelle. Ils substituent a une impulsion aleatoire, dont on cherche a mesurer l'instant d'arrivee par rapport a un instant pris pour origine, une autre impulsion dont la phase est bien determinee par rapport a celle d'une horloge prise comme reference. Le spectre temporel de sortie, retarde, peut toujours etre situe a l'interieur des canaux de largeur {delta}T, definis par l'horloge. La statistique temporelle des evenements analyses est toujours correcte, meme si la duree de transition des circuits definissant les canaux represente une grande fraction de {delta}T: le codage de temps devient parfait. Les circuits de mise en phase, utilises en chronometrie fine, sont tres employes en Physique Nucleaire car les spectres temporels oblenus sont representatifs

  4. How discriminating are discriminative instruments?

    Science.gov (United States)

    Hankins, Matthew

    2008-05-27

    The McMaster framework introduced by Kirshner & Guyatt is the dominant paradigm for the development of measures of health status and health-related quality of life (HRQL). The framework defines the functions of such instruments as evaluative, predictive or discriminative. Evaluative instruments are required to be sensitive to change (responsiveness), but there is no corresponding index of the degree to which discriminative instruments are sensitive to cross-sectional differences. This paper argues that indices of validity and reliability are not sufficient to demonstrate that a discriminative instrument performs its function of discriminating between individuals, and that the McMaster framework would be augmented by the addition of a separate index of discrimination. The coefficient proposed by Ferguson (Delta) is easily adapted to HRQL instruments and is a direct, non-parametric index of the degree to which an instrument distinguishes between individuals. While Delta should prove useful in the development and evaluation of discriminative instruments, further research is required to elucidate the relationship between the measurement properties of discrimination, reliability and responsiveness.

  5. How discriminating are discriminative instruments?

    Directory of Open Access Journals (Sweden)

    Hankins Matthew

    2008-05-01

    Full Text Available Abstract The McMaster framework introduced by Kirshner & Guyatt is the dominant paradigm for the development of measures of health status and health-related quality of life (HRQL. The framework defines the functions of such instruments as evaluative, predictive or discriminative. Evaluative instruments are required to be sensitive to change (responsiveness, but there is no corresponding index of the degree to which discriminative instruments are sensitive to cross-sectional differences. This paper argues that indices of validity and reliability are not sufficient to demonstrate that a discriminative instrument performs its function of discriminating between individuals, and that the McMaster framework would be augmented by the addition of a separate index of discrimination. The coefficient proposed by Ferguson (Delta is easily adapted to HRQL instruments and is a direct, non-parametric index of the degree to which an instrument distinguishes between individuals. While Delta should prove useful in the development and evaluation of discriminative instruments, further research is required to elucidate the relationship between the measurement properties of discrimination, reliability and responsiveness.

  6. Discrimination of Aspergillus isolates at the species and strain level by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry fingerprinting.

    Science.gov (United States)

    Hettick, Justin M; Green, Brett J; Buskirk, Amanda D; Kashon, Michael L; Slaven, James E; Janotka, Erika; Blachere, Francoise M; Schmechel, Detlef; Beezhold, Donald H

    2008-09-15

    Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) was used to generate highly reproducible mass spectral fingerprints for 12 species of fungi of the genus Aspergillus and 5 different strains of Aspergillus flavus. Prior to MALDI-TOF MS analysis, the fungi were subjected to three 1-min bead beating cycles in an acetonitrile/trifluoroacetic acid solvent. The mass spectra contain abundant peaks in the range of 5 to 20kDa and may be used to discriminate between species unambiguously. A discriminant analysis using all peaks from the MALDI-TOF MS data yielded error rates for classification of 0 and 18.75% for resubstitution and cross-validation methods, respectively. If a subset of 28 significant peaks is chosen, resubstitution and cross-validation error rates are 0%. Discriminant analysis of the MALDI-TOF MS data for 5 strains of A. flavus using all peaks yielded error rates for classification of 0 and 5% for resubstitution and cross-validation methods, respectively. These data indicate that MALDI-TOF MS data may be used for unambiguous identification of members of the genus Aspergillus at both the species and strain levels.

  7. Matrix-assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry (MALDI-TOF MS) Can Precisely Discriminate the Lineages of Listeria monocytogenes and Species of Listeria.

    Science.gov (United States)

    Ojima-Kato, Teruyo; Yamamoto, Naomi; Takahashi, Hajime; Tamura, Hiroto

    2016-01-01

    The genetic lineages of Listeria monocytogenes and other species of the genus Listeria are correlated with pathogenesis in humans. Although matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) has become a prevailing tool for rapid and reliable microbial identification, the precise discrimination of Listeria species and lineages remains a crucial issue in clinical settings and for food safety. In this study, we constructed an accurate and reliable MS database to discriminate the lineages of L. monocytogenes and the species of Listeria (L. monocytogenes, L. innocua, L. welshimeri, L. seeligeri, L. ivanovii, L. grayi, and L. rocourtiae) based on the S10-spc-alpha operon gene encoded ribosomal protein mass spectrum (S10-GERMS) proteotyping method, which relies on both genetic information (genomics) and observed MS peaks in MALDI-TOF MS (proteomics). The specific set of eight biomarkers (ribosomal proteins L24, L6, L18, L15, S11, S9, L31 type B, and S16) yielded characteristic MS patterns for the lineages of L. monocytogenes and the different species of Listeria, and led to the construction of a MS database that was successful in discriminating between these organisms in MALDI-TOF MS fingerprinting analysis followed by advanced proteotyping software Strain Solution analysis. We also confirmed the constructed database on the proteotyping software Strain Solution by using 23 Listeria strains collected from natural sources.

  8. LOGIC CIRCUIT

    Science.gov (United States)

    Strong, G.H.; Faught, M.L.

    1963-12-24

    A device for safety rod counting in a nuclear reactor is described. A Wheatstone bridge circuit is adapted to prevent de-energizing the hopper coils of a ball backup system if safety rods, sufficient in total control effect, properly enter the reactor core to effect shut down. A plurality of resistances form one arm of the bridge, each resistance being associated with a particular safety rod and weighted in value according to the control effect of the particular safety rod. Switching means are used to switch each of the resistances in and out of the bridge circuit responsive to the presence of a particular safety rod in its effective position in the reactor core and responsive to the attainment of a predetermined velocity by a particular safety rod enroute to its effective position. The bridge is unbalanced in one direction during normal reactor operation prior to the generation of a scram signal and the switching means and resistances are adapted to unbalance the bridge in the opposite direction if the safety rods produce a predetermined amount of control effect in response to the scram signal. The bridge unbalance reversal is then utilized to prevent the actuation of the ball backup system, or, conversely, a failure of the safety rods to produce the predetermined effect produces no unbalance reversal and the ball backup system is actuated. (AEC)

  9. Analysis of the effects of time delay in clock recovery circuits based on Phase-locked loops

    DEFF Research Database (Denmark)

    Zibar, Darko; Oxenløwe, Leif Katsuo; Clausen, Anders

    2004-01-01

    Influence of time delay in a balanced optical phase-locked loops (OPLL) with a proportional integrator (Pl) filter is investigated using a delayed differential equation (DDE) is investigated. The limitations, which a time delay imposes on the Pl filter bandwidth, at increasing values of loop gain...

  10. Implementation of Chua's circuit using simulated inductance

    Science.gov (United States)

    Gopakumar, K.; Premlet, B.; Gopchandran, K. G.

    2011-05-01

    In this study we describe how to build an inductorless version of the classic Chua's circuit. A suitable inductor for Chua's circuit is often hard to procure. The required inductor for the circuit is designed using simple circuit elements such as resistors, capacitors and operational amplifiers. The complete circuit can be implemented by using off-the-shelf components, and it can readily be integrated on a single chip. This design of Chua's circuit allows the original dynamics to be slowed down to just a few hertz, enabling implementation of sophisticated control schemes without severe time restrictions. Another novel feature of the circuit is that losses associated with capacitors due to leakages can easily be compensated by providing negative resistance using the same setup. The chaotic behaviour of the circuit is verified by PSpice and Multisim simulation and also by experimental study on a circuit breadboard. The results give excellent agreement with each other and with the results of previous investigators.

  11. Short- circuit tests of circuit breakers

    OpenAIRE

    Chorovský, P.

    2015-01-01

    This paper deals with short-circuit tests of low voltage electrical devices. In the first part of this paper, there are described basic types of short- circuit tests and their principles. Direct and indirect (synthetic) tests with more details are described in the second part. Each test and principles are explained separately. Oscilogram is obtained from short-circuit tests of circuit breakers at laboratory. The aim of this research work is to propose a test circuit for performing indirect test.

  12. Advanced circuit simulation using Multisim workbench

    CERN Document Server

    Báez-López, David; Cervantes-Villagómez, Ofelia Delfina

    2012-01-01

    Multisim is now the de facto standard for circuit simulation. It is a SPICE-based circuit simulator which combines analog, discrete-time, and mixed-mode circuits. In addition, it is the only simulator which incorporates microcontroller simulation in the same environment. It also includes a tool for printed circuit board design.Advanced Circuit Simulation Using Multisim Workbench is a companion book to Circuit Analysis Using Multisim, published by Morgan & Claypool in 2011. This new book covers advanced analyses and the creation of models and subcircuits. It also includes coverage of transmissi

  13. Collective of mechatronics circuit

    International Nuclear Information System (INIS)

    1987-02-01

    This book is composed of three parts, which deals with mechatronics system about sensor, circuit and motor. The contents of the first part are photo sensor of collector for output, locating detection circuit with photo interrupts, photo sensor circuit with CdS cell and lamp, interface circuit with logic and LED and temperature sensor circuit. The second part deals with oscillation circuit with crystal, C-R oscillation circuit, F-V converter, timer circuit, stability power circuit, DC amp and DC-DC converter. The last part is comprised of bridge server circuit, deformation bridge server, controlling circuit of DC motor, controlling circuit with IC for PLL and driver circuit of stepping motor and driver circuit of Brushless.

  14. Collective of mechatronics circuit

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1987-02-15

    This book is composed of three parts, which deals with mechatronics system about sensor, circuit and motor. The contents of the first part are photo sensor of collector for output, locating detection circuit with photo interrupts, photo sensor circuit with CdS cell and lamp, interface circuit with logic and LED and temperature sensor circuit. The second part deals with oscillation circuit with crystal, C-R oscillation circuit, F-V converter, timer circuit, stability power circuit, DC amp and DC-DC converter. The last part is comprised of bridge server circuit, deformation bridge server, controlling circuit of DC motor, controlling circuit with IC for PLL and driver circuit of stepping motor and driver circuit of Brushless.

  15. Parameter estimation methods for gene circuit modeling from time-series mRNA data: a comparative study

    KAUST Repository

    Fan, M.; Kuwahara, Hiroyuki; Wang, X.; Wang, S.; Gao, Xin

    2015-01-01

    Parameter estimation is a challenging computational problemin the reverse engineering of biological systems. Because advances in biotechnology have facilitated wide availability of time-series gene expression data, systematic parameter esti- mation

  16. Improvement in limit of detection in particle induced X-ray emission by means of rise time and pulse shape discrimination

    Energy Technology Data Exchange (ETDEWEB)

    Papp, Tibor E-mail: tibpapp@netscape.nettibpapp@yahoo.ca; Lakatos, Tamas; Nejedly, Zdenek; Campbell, John L

    2002-04-01

    A digital signal processor, based upon high-rate sampling of the preamplifier output, and equipped with rise time and pulse shape discrimination, has been tested in three situations. This processor provided significant improvement of particle induced X-ray emission and X-ray fluorescence detection limits over the state of the art analog processors, depending on the energy and intensity distribution of the X-ray spectra. Additionally it had a superior performance when measurements were performed in an environment of large electronic noise and in large nuclear background environment. It has also improved the reduction of several artifacts in X-ray spectra.

  17. Circuit parties.

    Science.gov (United States)

    Guzman, R

    2000-03-01

    Circuit parties are extended celebrations, lasting from a day to a week, primarily attended by gay and bisexual men in their thirties and forties. These large-scale dance parties move from city to city and draw thousands of participants. The risks for contracting HIV during these parties include recreational drug use and unsafe sex. Limited data exists on the level of risk at these parties, and participants are skeptical of outside help because of past criticism of these events. Health care and HIV advocates can promote risk-reduction strategies with the cooperation of party planners and can counsel individuals to personally reduce their own risk. To convey the message, HIV prevention workers should emphasize positive and community-centered aspects of the parties, such as taking care of friends and avoiding overdose.

  18. Note: Electronic circuit for two-way time transfer via a single coaxial cable with picosecond accuracy and precision

    Czech Academy of Sciences Publication Activity Database

    Pánek, Petr; Procházka, I.; Kodet, J.

    2012-01-01

    Roč. 83, č. 11 (2012), s. 1161041-1161043 ISSN 0034-6748 R&D Projects: GA MPO(CZ) FR-TI3/453 Institutional support: RVO:67985882 Keywords : time measurement Subject RIV: JA - Electronics ; Optoelectronics, Electrical Engineering Impact factor: 1.602, year: 2012

  19. CMOS digital integrated circuits a first course

    CERN Document Server

    Hawkins, Charles; Zarkesh-Ha, Payman

    2016-01-01

    This book teaches the fundamentals of modern CMOS technology and covers equal treatment to both types of MOSFET transistors that make up computer circuits; power properties of logic circuits; physical and electrical properties of metals; introduction of timing circuit electronics and introduction of layout; real-world examples and problem sets.

  20. Radiation-sensitive switching circuits

    Energy Technology Data Exchange (ETDEWEB)

    Moore, J.H.; Cockshott, C.P.

    1976-03-16

    A radiation-sensitive switching circuit includes a light emitting diode which from time to time illuminates a photo-transistor, the photo-transistor serving when its output reaches a predetermined value to operate a trigger circuit. In order to allow for aging of the components, the current flow through the diode is increased when the output from the transistor falls below a known level. Conveniently, this is achieved by having a transistor in parallel with the diode, and turning the transistor off when the output from the phototransistor becomes too low. The circuit is designed to control the ignition system in an automobile engine.

  1. A chaotic jerk system with non-hyperbolic equilibrium: Dynamics, effect of time delay and circuit realisation

    Science.gov (United States)

    Rajagopal, Karthikeyan; Pham, Viet-Thanh; Tahir, Fadhil Rahma; Akgul, Akif; Abdolmohammadi, Hamid Reza; Jafari, Sajad

    2018-04-01

    The literature on chaos has highlighted several chaotic systems with special features. In this work, a novel chaotic jerk system with non-hyperbolic equilibrium is proposed. The dynamics of this new system is revealed through equilibrium analysis, phase portrait, bifurcation diagram and Lyapunov exponents. In addition, we investigate the time-delay effects on the proposed system. Realisation of such a system is presented to verify its feasibility.

  2. Commutation circuit for an HVDC circuit breaker

    Science.gov (United States)

    Premerlani, William J.

    1981-01-01

    A commutation circuit for a high voltage DC circuit breaker incorporates a resistor capacitor combination and a charging circuit connected to the main breaker, such that a commutating capacitor is discharged in opposition to the load current to force the current in an arc after breaker opening to zero to facilitate arc interruption. In a particular embodiment, a normally open commutating circuit is connected across the contacts of a main DC circuit breaker to absorb the inductive system energy trapped by breaker opening and to limit recovery voltages to a level tolerable by the commutating circuit components.

  3. Trip electrical circuit of the gyrotion

    International Nuclear Information System (INIS)

    Rossi, J.O.

    1987-09-01

    The electron cyclotron resonance heating system of INPE/LAP is shown and the trip electrical circuit of the gyrotron is described, together with its fundamental aspects. The trip electrical circuit consists basically of a series regulator circuit which regulates the output voltage level and controls the pulse width time. Besides that, a protection circuit for both tubes, regulator and gyrotron, against faults in the system. (author) [pt

  4. Real-time sensing and discrimination of single chemicals using the channel of phi29 DNA packaging nanomotor.

    Science.gov (United States)

    Haque, Farzin; Lunn, Jennifer; Fang, Huaming; Smithrud, David; Guo, Peixuan

    2012-04-24

    A highly sensitive and reliable method to sense and identify a single chemical at extremely low concentrations and high contamination is important for environmental surveillance, homeland security, athlete drug monitoring, toxin/drug screening, and earlier disease diagnosis. This article reports a method for precise detection of single chemicals. The hub of the bacteriophage phi29 DNA packaging motor is a connector consisting of 12 protein subunits encircled into a 3.6 nm channel as a path for dsDNA to enter during packaging and to exit during infection. The connector has previously been inserted into a lipid bilayer to serve as a membrane-embedded channel. Herein we report the modification of the phi29 channel to develop a class of sensors to detect single chemicals. The lysine-234 of each protein subunit was mutated to cysteine, generating 12-SH ring lining the channel wall. Chemicals passing through this robust channel and interactions with the SH group generated extremely reliable, precise, and sensitive current signatures as revealed by single channel conductance assays. Ethane (57 Da), thymine (167 Da), and benzene (105 Da) with reactive thioester moieties were clearly discriminated upon interaction with the available set of cysteine residues. The covalent attachment of each analyte induced discrete stepwise blockage in current signature with a corresponding decrease in conductance due to the physical blocking of the channel. Transient binding of the chemicals also produced characteristic fingerprints that were deduced from the unique blockage amplitude and pattern of the signals. This study shows that the phi29 connector can be used to sense chemicals with reactive thioesters or maleimide using single channel conduction assays based on their distinct fingerprints. The results demonstrated that this channel system could be further developed into very sensitive sensing devices.

  5. Trigger circuit

    International Nuclear Information System (INIS)

    Verity, P.R.; Chaplain, M.D.; Turner, G.D.J.

    1984-01-01

    A monostable trigger circuit comprises transistors TR2 and TR3 arranged with their collectors and bases interconnected. The collector of the transistor TR2 is connected to the base of transistor TR3 via a capacitor C2 the main current path of a grounded base transistor TR1 and resistive means R2,R3. The collector of transistor TR3 is connected to the base of transistor TR2 via resistive means R6, R7. In the stable state all the transistors are OFF, the capacitor C2 is charged, and the output is LOW. A positive pulse input to the base of TR2 switches it ON, which in turn lowers the voltage at points A and B and so switches TR1 ON so that C2 can discharge via R2, R3, which in turn switches TR3 ON making the output high. Thus all three transistors are latched ON. When C2 has discharged sufficiently TR1 switches OFF, followed by TR3 (making the output low again) and TR2. The components C1, C3 and R4 serve to reduce noise, and the diode D1 is optional. (author)

  6. Integrated coincidence circuits

    International Nuclear Information System (INIS)

    Borejko, V.F.; Grebenyuk, V.M.; Zinov, V.G.

    1976-01-01

    The description is given of two coincidence units employing integral circuits in the VISHNYA standard. The units are distinguished for the coincidence selection element which is essentially a combination of a tunnel diode and microcircuits. The output fast response of the units is at least 90 MHz in the mode of the output signal unshaped in duration and 50 MHz minimum in the mode of the output signal shaping. The resolution time of the units is dependent upon the duration of input signals

  7. Developing a Domain Model for Relay Circuits

    DEFF Research Database (Denmark)

    Haxthausen, Anne Elisabeth

    2009-01-01

    In this paper we stepwise develop a domain model for relay circuits as used in railway control systems. First we provide an abstract, property-oriented model of networks consisting of components that can be glued together with connectors. This model is strongly inspired by a network model...... for railways madeby Bjørner et.al., however our model is more general: the components can be of any kind and can later be refined to e.g. railway components or circuit components. Then we show how the abstract network model can be refined into an explicit model for relay circuits. The circuit model describes...... the statics as well as the dynamics of relay circuits, i.e. how a relay circuit can be composed legally from electrical components as well as how the components may change state over time. Finally the circuit model is transformed into an executable model, and we show how a concrete circuit can be defined...

  8. Temporal discrimination, a cervical dystonia endophenotype: penetrance and functional correlates.

    Science.gov (United States)

    Kimmich, Okka; Molloy, Anna; Whelan, Robert; Williams, Laura; Bradley, David; Balsters, Joshua; Molloy, Fiona; Lynch, Tim; Healy, Daniel G; Walsh, Cathal; O'Riordan, Seán; Reilly, Richard B; Hutchinson, Michael

    2014-05-01

    The pathogenesis of adult-onset primary dystonia remains poorly understood. There is variable age-related and gender-related expression of the phenotype, the commonest of which is cervical dystonia. Endophenotypes may provide insight into underlying genetic and pathophysiological mechanisms of dystonia. The temporal discrimination threshold (TDT)-the shortest time interval at which two separate stimuli can be detected as being asynchronous-is abnormal both in patients with cervical dystonia and in their unaffected first-degree relatives. Functional magnetic resonance imaging (fMRI) studies have shown that putaminal activation positively correlates with the ease of temporal discrimination between two stimuli in healthy individuals. We hypothesized that abnormal temporal discrimination would exhibit similar age-related and gender-related penetrance as cervical dystonia and that unaffected relatives with an abnormal TDT would have reduced putaminal activation during a temporal discrimination task. TDTs were examined in a group of 192 healthy controls and in 158 unaffected first-degree relatives of 84 patients with cervical dystonia. In 24 unaffected first-degree relatives, fMRI scanning was performed during a temporal discrimination task. The prevalence of abnormal TDTs in unaffected female relatives reached 50% after age 48 years; whereas, in male relatives, penetrance of the endophenotype was reduced. By fMRI, relatives who had abnormal TDTs, compared with relatives who had normal TDTs, had significantly less activation in the putamina and in the middle frontal and precentral gyri. Only the degree of reduction of putaminal activity correlated significantly with worsening of temporal discrimination. These findings further support abnormal temporal discrimination as an endophenotype of cervical dystonia involving disordered basal ganglia circuits. © 2014 International Parkinson and Movement Disorder Society.

  9. First tests of the applicability of γ-ray imaging for background discrimination in time-of-flight neutron capture measurements

    Energy Technology Data Exchange (ETDEWEB)

    Pérez Magán, D.L.; Caballero, L. [IFIC, CSIC-Universidad de Valencia, E-46071 Valencia (Spain); Domingo-Pardo, C., E-mail: domingo@ific.uv.es [IFIC, CSIC-Universidad de Valencia, E-46071 Valencia (Spain); Agramunt-Ros, J.; Albiol, F. [IFIC, CSIC-Universidad de Valencia, E-46071 Valencia (Spain); Casanovas, A. [Institut de Tècniques Energètiques – Departament de Física i Enginyeria Nuclear, Universitat Politècnica de Catalunya, 08028 Barcelona (Spain); González, A. [Institute for Instrumentation in Molecular Imaging, I3M-CSIC 46022 Valencia (Spain); Guerrero, C.; Lerendegui-Marco, J. [Dto. de Física Atómica, Molecular y Nuclear, Universidad de Sevilla, 41012 Sevilla (Spain); Tarifeño-Saldivia, A. [IFIC, CSIC-Universidad de Valencia, E-46071 Valencia (Spain); Institut de Tècniques Energètiques – Departament de Física i Enginyeria Nuclear, Universitat Politècnica de Catalunya, 08028 Barcelona (Spain)

    2016-07-01

    In this work we explore for the first time the applicability of using γ-ray imaging in neutron capture measurements to identify and suppress spatially localized background. For this aim, a pinhole gamma camera is assembled, tested and characterized in terms of energy and spatial performance. It consists of a monolithic CeBr{sub 3} scintillating crystal coupled to a position-sensitive photomultiplier and readout through an integrated circuit AMIC2GR. The pinhole collimator is a massive carven block of lead. A series of dedicated measurements with calibrated sources and with a neutron beam incident on a {sup 197}Au sample have been carried out at n-TOF, achieving an enhancement of a factor of two in the signal-to-background ratio when selecting only those events coming from the direction of the sample.

  10. Detection and partial discrimination of atypical and classical bovine spongiform encephalopathies in cattle and primates using real-time quaking-induced conversion assay.

    Science.gov (United States)

    Levavasseur, Etienne; Biacabe, Anne-Gaëlle; Comoy, Emmanuel; Culeux, Audrey; Grznarova, Katarina; Privat, Nicolas; Simoneau, Steve; Flan, Benoit; Sazdovitch, Véronique; Seilhean, Danielle; Baron, Thierry; Haïk, Stéphane

    2017-01-01

    The transmission of classical bovine spongiform encephalopathy (C-BSE) through contaminated meat product consumption is responsible for variant Creutzfeldt-Jakob disease (vCJD) in humans. More recent and atypical forms of BSE (L-BSE and H-BSE) have been identified in cattle since the C-BSE epidemic. Their low incidence and advanced age of onset are compatible with a sporadic origin, as are most cases of Creutzfeldt-Jakob disease (CJD) in humans. Transmissions studies in primates and transgenic mice expressing a human prion protein (PrP) indicated that atypical forms of BSE may be associated with a higher zoonotic potential than classical BSE, and require particular attention for public health. Recently, methods designed to amplify misfolded forms of PrP have emerged as promising tools to detect prion strains and to study their diversity. Here, we validated real-time quaking-induced conversion assay for the discrimination of atypical and classical BSE strains using a large series of bovine samples encompassing all the atypical BSE cases detected by the French Centre of Reference during 10 years of exhaustive active surveillance. We obtained a 100% sensitivity and specificity for atypical BSE detection. In addition, the assay was able to discriminate atypical and classical BSE in non-human primates, and also sporadic CJD and vCJD in humans. The RT-QuIC assay appears as a practical means for a reliable detection of atypical BSE strains in a homologous or heterologous PrP context.

  11. Low level alpha activity measurements with pulse shape discrimination

    International Nuclear Information System (INIS)

    Satoh, Kaneaki; Higuchi, Hideo; Kitamura, Kiyoshi; Noguchi, Masayasu.

    1984-01-01

    Liquid scintillation counting of α rays with pulse shape discrimination was applied to the analysis of 226 Ra and 239+240 Pu in environmental samples and of α-emitters in/on a filter paper. The instrument used in this study was either a specially designed detector or a commercial liquid scintillation counter with an automatic sample changer, both of which were connected to the pulse shape discrimination circuit. The background counting rate in α energy region of 5-7 MeV was 0.01 or 0.04 cpm/MeV, respectively. The figure of merit indicating the resolving power for α- and β-particles in time spectrum was found to be 5.7 for the commercial liquid scintillation counter. (author)

  12. Discrimination of shot-noise-driven Poisson processes by external dead time - Application of radioluminescence from glass

    Science.gov (United States)

    Saleh, B. E. A.; Tavolacci, J. T.; Teich, M. C.

    1981-01-01

    Ways in which dead time can be used to constructively enhance or diminish the effects of point processes that display bunching in the shot-noise-driven doubly stochastic Poisson point process (SNDP) are discussed. Interrelations between photocount bunching arising in the SNDP and the antibunching character arising from dead-time effects are investigated. It is demonstrated that the dead-time-modified count mean and variance for an arbitrary doubly stochastic Poisson point process can be obtained from the Laplace transform of the single-fold and joint-moment-generating functions for the driving rate process. The theory is in good agreement with experimental values for radioluminescence radiation in fused silica, quartz, and glass, and the process has many applications in pulse, particle, and photon detection.

  13. Neuromorphic Silicon Neuron Circuits

    Science.gov (United States)

    Indiveri, Giacomo; Linares-Barranco, Bernabé; Hamilton, Tara Julia; van Schaik, André; Etienne-Cummings, Ralph; Delbruck, Tobi; Liu, Shih-Chii; Dudek, Piotr; Häfliger, Philipp; Renaud, Sylvie; Schemmel, Johannes; Cauwenberghs, Gert; Arthur, John; Hynna, Kai; Folowosele, Fopefolu; Saighi, Sylvain; Serrano-Gotarredona, Teresa; Wijekoon, Jayawan; Wang, Yingxue; Boahen, Kwabena

    2011-01-01

    Hardware implementations of spiking neurons can be extremely useful for a large variety of applications, ranging from high-speed modeling of large-scale neural systems to real-time behaving systems, to bidirectional brain–machine interfaces. The specific circuit solutions used to implement silicon neurons depend on the application requirements. In this paper we describe the most common building blocks and techniques used to implement these circuits, and present an overview of a wide range of neuromorphic silicon neurons, which implement different computational models, ranging from biophysically realistic and conductance-based Hodgkin–Huxley models to bi-dimensional generalized adaptive integrate and fire models. We compare the different design methodologies used for each silicon neuron design described, and demonstrate their features with experimental results, measured from a wide range of fabricated VLSI chips. PMID:21747754

  14. Neuromorphic silicon neuron circuits

    Directory of Open Access Journals (Sweden)

    Giacomo eIndiveri

    2011-05-01

    Full Text Available Hardware implementations of spiking neurons can be extremely useful for a large variety of applications, ranging from high-speed modeling of large-scale neural systems to real-time behaving systems, to bidirectional brain-machine interfaces. The specific circuit solutions used to implement silicon neurons depend on the application requirements. In this paper we describe the most common building blocks and techniques used to implement these circuits, and present an overview of a wide range of neuromorphic silicon neurons, which implement different computational models, ranging from biophysically realistic and conductance based Hodgkin-Huxley models to bi-dimensional generalized adaptive Integrate and Fire models. We compare the different design methodologies used for each silicon neuron design described, and demonstrate their features with experimental results, measured from a wide range of fabricated VLSI chips.

  15. Variational integrators for electric circuits

    International Nuclear Information System (INIS)

    Ober-Blöbaum, Sina; Tao, Molei; Cheng, Mulin; Owhadi, Houman; Marsden, Jerrold E.

    2013-01-01

    In this contribution, we develop a variational integrator for the simulation of (stochastic and multiscale) electric circuits. When considering the dynamics of an electric circuit, one is faced with three special situations: 1. The system involves external (control) forcing through external (controlled) voltage sources and resistors. 2. The system is constrained via the Kirchhoff current (KCL) and voltage laws (KVL). 3. The Lagrangian is degenerate. Based on a geometric setting, an appropriate variational formulation is presented to model the circuit from which the equations of motion are derived. A time-discrete variational formulation provides an iteration scheme for the simulation of the electric circuit. Dependent on the discretization, the intrinsic degeneracy of the system can be canceled for the discrete variational scheme. In this way, a variational integrator is constructed that gains several advantages compared to standard integration tools for circuits; in particular, a comparison to BDF methods (which are usually the method of choice for the simulation of electric circuits) shows that even for simple LCR circuits, a better energy behavior and frequency spectrum preservation can be observed using the developed variational integrator

  16. Design of analog integrated circuits and systems

    CERN Document Server

    Laker, Kenneth R

    1994-01-01

    This text is designed for senior or graduate level courses in analog integrated circuits or design of analog integrated circuits. This book combines consideration of CMOS and bipolar circuits into a unified treatment. Also included are CMOS-bipolar circuits made possible by BiCMOS technology. The text progresses from MOS and bipolar device modelling to simple one and two transistor building block circuits. The final two chapters present a unified coverage of sample-data and continuous-time signal processing systems.

  17. Time-order errors and standard-position effects in duration discrimination: An experimental study and an analysis by the sensation-weighting model.

    Science.gov (United States)

    Hellström, Åke; Rammsayer, Thomas H

    2015-10-01

    Studies have shown that the discriminability of successive time intervals depends on the presentation order of the standard (St) and the comparison (Co) stimuli. Also, this order affects the point of subjective equality. The first effect is here called the standard-position effect (SPE); the latter is known as the time-order error. In the present study, we investigated how these two effects vary across interval types and standard durations, using Hellström's sensation-weighting model to describe the results and relate them to stimulus comparison mechanisms. In Experiment 1, four modes of interval presentation were used, factorially combining interval type (filled, empty) and sensory modality (auditory, visual). For each mode, two presentation orders (St-Co, Co-St) and two standard durations (100 ms, 1,000 ms) were used; half of the participants received correctness feedback, and half of them did not. The interstimulus interval was 900 ms. The SPEs were negative (i.e., a smaller difference limen for St-Co than for Co-St), except for the filled-auditory and empty-visual 100-ms standards, for which a positive effect was obtained. In Experiment 2, duration discrimination was investigated for filled auditory intervals with four standards between 100 and 1,000 ms, an interstimulus interval of 900 ms, and no feedback. Standard duration interacted with presentation order, here yielding SPEs that were negative for standards of 100 and 1,000 ms, but positive for 215 and 464 ms. Our findings indicate that the SPE can be positive as well as negative, depending on the interval type and standard duration, reflecting the relative weighting of the stimulus information, as is described by the sensation-weighting model.

  18. Discriminating the Mediterranean Pinus spp. using the land surface phenology extracted from the whole MODIS NDVI time series and machine learning algorithms

    Science.gov (United States)

    Rodriguez-Galiano, Victor; Aragones, David; Caparros-Santiago, Jose A.; Navarro-Cerrillo, Rafael M.

    2017-10-01

    Land surface phenology (LSP) can improve the characterisation of forest areas and their change processes. The aim of this work was: i) to characterise the temporal dynamics in Mediterranean Pinus forests, and ii) to evaluate the potential of LSP for species discrimination. The different experiments were based on 679 mono-specific plots for the 5 native species on the Iberian Peninsula: P. sylvestris, P. pinea, P. halepensis, P. nigra and P. pinaster. The entire MODIS NDVI time series (2000-2016) of the MOD13Q1 product was used to characterise phenology. The following phenological parameters were extracted: the start, end and median days of the season, and the length of the season in days, as well as the base value, maximum value, amplitude and integrated value. Multi-temporal metrics were calculated to synthesise the inter-annual variability of the phenological parameters. The species were discriminated by the application of Random Forest (RF) classifiers from different subsets of variables: model 1) NDVI-smoothed time series, model 2) multi-temporal metrics of the phenological parameters, and model 3) multi-temporal metrics and the auxiliary physical variables (altitude, slope, aspect and distance to the coastline). Model 3 was the best, with an overall accuracy of 82%, a kappa coefficient of 0.77 and whose most important variables were: elevation, coast distance, and the end and start days of the growing season. The species that presented the largest errors was P. nigra, (kappa= 0.45), having locations with a similar behaviour to P. sylvestris or P. pinaster.

  19. Real-Time Landmine Detection with Ground-Penetrating Radar Using Discriminative and Adaptive Hidden Markov Models

    Directory of Open Access Journals (Sweden)

    Ho KC

    2005-01-01

    Full Text Available We propose a real-time software system for landmine detection using ground-penetrating radar (GPR. The system includes an efficient and adaptive preprocessing component; a hidden Markov model- (HMM- based detector; a corrective training component; and an incremental update of the background model. The preprocessing is based on frequency-domain processing and performs ground-level alignment and background removal. The HMM detector is an improvement of a previously proposed system (baseline. It includes additional pre- and postprocessing steps to improve the time efficiency and enable real-time application. The corrective training component is used to adjust the initial model parameters to minimize the number of misclassification sequences. This component could be used offline, or online through feedback to adapt an initial model to specific sites and environments. The background update component adjusts the parameters of the background model to adapt it to each lane during testing. The proposed software system is applied to data acquired from three outdoor test sites at different geographic locations, using a state-of-the-art array GPR prototype. The first collection was used as training, and the other two (contain data from more than 1200 m of simulated dirt and gravel roads for testing. Our results indicate that, on average, the corrective training can improve the performance by about 10% for each site. For individual lanes, the performance gain can reach 50%.

  20. Discrimination aware decision tree learning

    NARCIS (Netherlands)

    Kamiran, F.; Calders, T.G.K.; Pechenizkiy, M.

    2010-01-01

    Recently, the following problem of discrimination aware classification was introduced: given a labeled dataset and an attribute B, find a classifier with high predictive accuracy that at the same time does not discriminate on the basis of the given attribute B. This problem is motivated by the fact

  1. Discrimination aware decision tree learning

    NARCIS (Netherlands)

    Kamiran, F.; Calders, T.G.K.; Pechenizkiy, M.

    2010-01-01

    Recently, the following discrimination aware classification problem was introduced: given a labeled dataset and an attribute B, find a classifier with high predictive accuracy that at the same time does not discriminate on the basis of the given attribute B. This problem is motivated by the fact

  2. BurkDiff: a real-time PCR allelic discrimination assay for Burkholderia pseudomallei and B. mallei.

    Directory of Open Access Journals (Sweden)

    Jolene R Bowers

    2010-11-01

    Full Text Available A real-time PCR assay, BurkDiff, was designed to target a unique conserved region in the B. pseudomallei and B. mallei genomes containing a SNP that differentiates the two species. Sensitivity and specificity were assessed by screening BurkDiff across 469 isolates of B. pseudomallei, 49 isolates of B. mallei, and 390 isolates of clinically relevant non-target species. Concordance of results with traditional speciation methods and no cross-reactivity to non-target species show BurkDiff is a robust, highly validated assay for the detection and differentiation of B. pseudomallei and B. mallei.

  3. Volatile Discrimination of Irradiated and Fumigated White Ginseng Powders at Different Storage Times and Temperatures Using the Electronic Nose

    International Nuclear Information System (INIS)

    Kwon, J.H.; Shin, J.A.; Lee, K.T.

    2006-01-01

    The pattern of volatile emissions from white ginseng powders (WGP) that were treated with selected preservatives was investigated during 5-months of storage (at-10 and 25℃) by an electronic nose system equipped with 12 metal-oxide sensors. WGP were treated with gamma radiation at 5 kGy, commercial methyl bromide (MeBr), and phosphine fumigations. Electronic nose differentiated the volatile patterns of the WGP with each different preservative treatment. In addition, each volatile pattern was affected by both storage time (1, 2 and 5 months) and temperature (-10 and 25℃)

  4. Solid-state circuits

    CERN Document Server

    Pridham, G J

    2013-01-01

    Solid-State Circuits provides an introduction to the theory and practice underlying solid-state circuits, laying particular emphasis on field effect transistors and integrated circuits. Topics range from construction and characteristics of semiconductor devices to rectification and power supplies, low-frequency amplifiers, sine- and square-wave oscillators, and high-frequency effects and circuits. Black-box equivalent circuits of bipolar transistors, physical equivalent circuits of bipolar transistors, and equivalent circuits of field effect transistors are also covered. This volume is divided

  5. Circuit analysis for dummies

    CERN Document Server

    Santiago, John

    2013-01-01

    Circuits overloaded from electric circuit analysis? Many universities require that students pursuing a degree in electrical or computer engineering take an Electric Circuit Analysis course to determine who will ""make the cut"" and continue in the degree program. Circuit Analysis For Dummies will help these students to better understand electric circuit analysis by presenting the information in an effective and straightforward manner. Circuit Analysis For Dummies gives you clear-cut information about the topics covered in an electric circuit analysis courses to help

  6. A novel and discriminative method of in vitro disintegration time for preparation and optimization of taste-masked orally disintegrating tablets of carbinoxamine maleate.

    Science.gov (United States)

    Liu, Yali; Li, Peng; Qian, Rong; Sun, Tianyu; Fang, Fangzhi; Wang, Zonghua; Ke, Xue; Xu, Bohui

    2018-08-01

    The primary objective of this study was to mask bitter taste and decrease the disintegration time of carbinoxamine maleate (CAM) orally disintegrating tablets (ODTs). In order to screen the prescription of ODTs, a novel modified in vitro disintegration method (MIVDM) was developed to measure the in vitro disintegration time. In this method, different concentrations of ethanol served as disintegration medium in order to delay the in vitro water absorption and disintegration process of tablets. The MIVDM demonstrated good in vitro and in vivo correlation and proved more precise and discriminative than other reported methods. In this research, ion exchange resins (IERs) were used to mask bitter taste for improving mouthfeel. The drug-resin ratio and reaction temperature were investigated to obtain the optimum carbinoxamine resin complexes (CRCs). The characterization of CRCs revealed an amorphous state. ODTs were prepared by direct compression. Superdisintegrants and diluents of ODTs were screened first. Further optimization was carried out by using Box-Behnken design. The effect of (X 1 ) mannitol/microcrystalline cellulose ratio, (X 2 ) the amount of low-substituted hydroxypropylcellulose and (X 3 ) the hardness was investigated for achieving the lowest (Y) in vitro disintegration time. Technological characterization, wetting time, water absorption ratio, and roughness degree were evaluated. The CRCs and ODTs proved successful taste-masking efficiency. The end product improved patients' compliance. The developed MIVDM was practical for commercial use.

  7. Analysis of time resolution in a dual head LSO+PSPMT PET system using low pass filter interpolation and digital constant fraction discriminator techniques

    International Nuclear Information System (INIS)

    Monzo, Jose M.; Lerche, Christoph W.; Martinez, Jorge D.; Esteve, Raul; Toledo, Jose; Gadea, Rafael; Colom, Ricardo J.; Herrero, Vicente; Ferrando, Nestor; Aliaga, Ramon J.; Mateo, Fernando; Sanchez, Filomeno; Mora, Francisco J.; Benlloch, Jose M.; Sebastia, Angel

    2009-01-01

    PET systems need good time resolution to improve the true event rate, random event rejection, and pile-up rejection. In this study we propose a digital procedure for this task using a low pass filter interpolation plus a Digital Constant Fraction Discriminator (DCFD). We analyzed the best way to implement this algorithm on our dual head PET system and how varying the quality of the acquired signal and electronic noise analytically affects timing resolution. Our detector uses two continuous LSO crystals with a position sensitive PMT. Six signals per detector are acquired using an analog electronics front-end and these signals are processed using an in-house digital acquisition board. The test bench developed simulates the electronics and digital algorithms using Matlab. Results show that electronic noise and other undesired effects have a significant effect on the timing resolution of the system. Interpolated DCFD gives better results than non-interpolated DCFD. In high noise environments, differences are reduced. An optimum delay selection, based on the environment noise, improves time resolution.

  8. Analysis of time resolution in a dual head LSO+PSPMT PET system using low pass filter interpolation and digital constant fraction discriminator techniques

    Energy Technology Data Exchange (ETDEWEB)

    Monzo, Jose M. [Digital Systems Design (DSD) Group, ITACA Institute, Universidad Politecnica de Valencia, Camino de Vera s/n, 46022 Valencia (Spain)], E-mail: jmonfer@aaa.upv.es; Lerche, Christoph W.; Martinez, Jorge D.; Esteve, Raul; Toledo, Jose; Gadea, Rafael; Colom, Ricardo J.; Herrero, Vicente; Ferrando, Nestor; Aliaga, Ramon J.; Mateo, Fernando [Digital Systems Design (DSD) Group, ITACA Institute, Universidad Politecnica de Valencia, Camino de Vera s/n, 46022 Valencia (Spain); Sanchez, Filomeno [Nuclear Medical Physics Group, IFIC Institute, Consejo Superior de Investigaciones Cientificas (CSIC), 46980 Paterna (Spain); Mora, Francisco J. [Digital Systems Design (DSD) Group, ITACA Institute, Universidad Politecnica de Valencia, Camino de Vera s/n, 46022 Valencia (Spain); Benlloch, Jose M. [Nuclear Medical Physics Group, IFIC Institute, Consejo Superior de Investigaciones Cientificas (CSIC), 46980 Paterna (Spain); Sebastia, Angel [Digital Systems Design (DSD) Group, ITACA Institute, Universidad Politecnica de Valencia, Camino de Vera s/n, 46022 Valencia (Spain)

    2009-06-01

    PET systems need good time resolution to improve the true event rate, random event rejection, and pile-up rejection. In this study we propose a digital procedure for this task using a low pass filter interpolation plus a Digital Constant Fraction Discriminator (DCFD). We analyzed the best way to implement this algorithm on our dual head PET system and how varying the quality of the acquired signal and electronic noise analytically affects timing resolution. Our detector uses two continuous LSO crystals with a position sensitive PMT. Six signals per detector are acquired using an analog electronics front-end and these signals are processed using an in-house digital acquisition board. The test bench developed simulates the electronics and digital algorithms using Matlab. Results show that electronic noise and other undesired effects have a significant effect on the timing resolution of the system. Interpolated DCFD gives better results than non-interpolated DCFD. In high noise environments, differences are reduced. An optimum delay selection, based on the environment noise, improves time resolution.

  9. Current limiter circuit system

    Science.gov (United States)

    Witcher, Joseph Brandon; Bredemann, Michael V.

    2017-09-05

    An apparatus comprising a steady state sensing circuit, a switching circuit, and a detection circuit. The steady state sensing circuit is connected to a first, a second and a third node. The first node is connected to a first device, the second node is connected to a second device, and the steady state sensing circuit causes a scaled current to flow at the third node. The scaled current is proportional to a voltage difference between the first and second node. The switching circuit limits an amount of current that flows between the first and second device. The detection circuit is connected to the third node and the switching circuit. The detection circuit monitors the scaled current at the third node and controls the switching circuit to limit the amount of the current that flows between the first and second device when the scaled current is greater than a desired level.

  10. High voltage short plus generation based on avalanche circuit

    International Nuclear Information System (INIS)

    Hu Yuanfeng; Yu Xiaoqi

    2006-01-01

    Simulate the avalanche circuit in series with PSPICE module, design the high voltage short plus generation circuit by avalanche transistor in series for the sweep deflection circuit of streak camera. The output voltage ranges 1.2 KV into 50 ohm load. The rise time of the circuit is less than 3 ns. (authors)

  11. Differential transimpedance amplifier circuit for correlated differential amplification

    Science.gov (United States)

    Gresham, Christopher A [Albuquerque, NM; Denton, M Bonner [Tucson, AZ; Sperline, Roger P [Tucson, AZ

    2008-07-22

    A differential transimpedance amplifier circuit for correlated differential amplification. The amplifier circuit increase electronic signal-to-noise ratios in charge detection circuits designed for the detection of very small quantities of electrical charge and/or very weak electromagnetic waves. A differential, integrating capacitive transimpedance amplifier integrated circuit comprising capacitor feedback loops performs time-correlated subtraction of noise.

  12. DICE based flip-flop with SET pulse discriminator on a 90 nm bulk CMOS process

    International Nuclear Information System (INIS)

    Maru, A.; Kuboyama, S.; Shindou, H.; Ebihara, T.; Tamura, T.; Makihara, A.; Hirao, Toshio

    2010-01-01

    In recent years, due to the demand for increased integration and device scaling, integrated circuits have been designed with the design rule less than 100 nm. In such integrated circuits, SEUs and SETs are serious problems because their supply voltage and the threshold voltage of the transistors are decreased. A DICE-based flip-flop with a SET pulse discriminator circuit on a 90-nm bulk CMOS was designed and fabricated. Its improved performance was demonstrated through radiation testing and discussion. SEU sensitivity for the angled irradiation was measured and discussed in this study. The test of edge-on irradiation was performed for the first time. The importance of the angled irradiation for the memory cells that have redundant memory nodes was demonstrated. (author)

  13. Similar circuits but different connectivity patterns between the cerebellum, basal ganglia, and supplementary motor area in early Parkinson's disease patients and controls during predictive motor timing.

    Science.gov (United States)

    Husárová, Ivica; Mikl, Michal; Lungu, Ovidiu V; Mareček, Radek; Vaníček, Jiří; Bareš, Martin

    2013-10-01

    subjects and controls use similar functional circuits to maintain a successful outcome in predictive motor timing behavior, the type and strength of EC and its modulation by behavioral performance differ between these two groups. These functional differences might represent the first step of cortical reorganization aimed at maintaining a normal performance in the brain affected by early Parkinson's disease and may have implications for the neuro-rehabilitation field. Copyright © 2013 by the American Society of Neuroimaging.

  14. Perceived weight discrimination and obesity.

    Directory of Open Access Journals (Sweden)

    Angelina R Sutin

    Full Text Available Weight discrimination is prevalent in American society. Although associated consistently with psychological and economic outcomes, less is known about whether weight discrimination is associated with longitudinal changes in obesity. The objectives of this research are (1 to test whether weight discrimination is associated with risk of becoming obese (Body Mass Index≥30; BMI by follow-up among those not obese at baseline, and (2 to test whether weight discrimination is associated with risk of remaining obese at follow-up among those already obese at baseline. Participants were drawn from the Health and Retirement Study, a nationally representative longitudinal survey of community-dwelling US residents. A total of 6,157 participants (58.6% female completed the discrimination measure and had weight and height available from the 2006 and 2010 assessments. Participants who experienced weight discrimination were approximately 2.5 times more likely to become obese by follow-up (OR = 2.54, 95% CI = 1.58-4.08 and participants who were obese at baseline were three times more likely to remain obese at follow up (OR = 3.20, 95% CI = 2.06-4.97 than those who had not experienced such discrimination. These effects held when controlling for demographic factors (age, sex, ethnicity, education and when baseline BMI was included as a covariate. These effects were also specific to weight discrimination; other forms of discrimination (e.g., sex, race were unrelated to risk of obesity at follow-up. The present research demonstrates that, in addition to poorer mental health outcomes, weight discrimination has implications for obesity. Rather than motivating individuals to lose weight, weight discrimination increases risk for obesity.

  15. CASTOR a VLSI CMOS mixed analog-digital circuit for low noise multichannel counting applications

    International Nuclear Information System (INIS)

    Comes, G.; Loddo, F.; Hu, Y.; Kaplon, J.; Ly, F.; Turchetta, R.; Bonvicini, V.; Vacchi, A.

    1996-01-01

    In this paper we present the design and first experimental results of a VLSI mixed analog-digital 1.2 microns CMOS circuit (CASTOR) for multichannel radiation detectors applications demanding low noise amplification and counting of radiation pulses. This circuit is meant to be connected to pixel-like detectors. Imaging can be obtained by counting the number of hits in each pixel during a user-controlled exposure time. Each channel of the circuit features an analog and a digital part. In the former one, a charge preamplifier is followed by a CR-RC shaper with an output buffer and a threshold discriminator. In the digital part, a 16-bit counter is present together with some control logic. The readout of the counters is done serially on a common tri-state output. Daisy-chaining is possible. A 4-channel prototype has been built. This prototype has been optimised for use in the digital radiography Syrmep experiment at the Elettra synchrotron machine in Trieste (Italy): its main design parameters are: shaping time of about 850 ns, gain of 190 mV/fC and ENC (e - rms)=60+17 C (pF). The counting rate per channel, limited by the analog part, can be as high as about 200 kHz. Characterisation of the circuit and first tests with silicon microstrip detectors are presented. They show the circuit works according to design specification and can be used for imaging applications. (orig.)

  16. DISCRIMINATION BY ASSOCIATION IN EUROPEAN LAW

    Directory of Open Access Journals (Sweden)

    Cătălina-Adriana Ivănuș

    2013-11-01

    Full Text Available The european law prohibit direct and indirect discrimination and harrasment on grounds of sex, racial or ethnic, religion or belief, disability, age or sexual orientation. The question is what is the situation when someone is discriminated on can claim to be the victim of unlawful discrimination because he or she is associated with another person who has the protected characteristic. The the Court of Justice of the European Union’s judgment in Coleman v Attridge Law and Steve Law confirms, for the first time in European law, the existence of the concept of discrimination by association. In this article I examine the implications of this case on all conceps of discrimination concepts of discrimination in European law (direct discrimination, indirect discrimination and harassment. I also examine the application of discrimination by association to grounds other than disability.

  17. Novel Accurate Bacterial Discrimination by MALDI-Time-of-Flight MS Based on Ribosomal Proteins Coding in S10-spc-alpha Operon at Strain Level S10-GERMS

    Science.gov (United States)

    Tamura, Hiroto; Hotta, Yudai; Sato, Hiroaki

    2013-08-01

    Matrix-assisted laser-desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) is one of the most widely used mass-based approaches for bacterial identification and classification because of the simple sample preparation and extremely rapid analysis within a few minutes. To establish the accurate MALDI-TOF MS bacterial discrimination method at strain level, the ribosomal subunit proteins coded in the S 10-spc-alpha operon, which encodes half of the ribosomal subunit protein and is highly conserved in eubacterial genomes, were selected as reliable biomarkers. This method, named the S10-GERMS method, revealed that the strains of genus Pseudomonas were successfully identified and discriminated at species and strain levels, respectively; therefore, the S10-GERMS method was further applied to discriminate the pathovar of P. syringae. The eight selected biomarkers (L24, L30, S10, S12, S14, S16, S17, and S19) suggested the rapid discrimination of P. syringae at the strain (pathovar) level. The S10-GERMS method appears to be a powerful tool for rapid and reliable bacterial discrimination and successful phylogenetic characterization. In this article, an overview of the utilization of results from the S10-GERMS method is presented, highlighting the characterization of the Lactobacillus casei group and discrimination of the bacteria of genera Bacillus and Sphingopyxis despite only two and one base difference in the 16S rRNA gene sequence, respectively.

  18. Selective post-training time window for memory consolidation interference of cannabidiol into the prefrontal cortex: Reduced dopaminergic modulation and immediate gene expression in limbic circuits.

    Science.gov (United States)

    Rossignoli, Matheus Teixeira; Lopes-Aguiar, Cleiton; Ruggiero, Rafael Naime; Do Val da Silva, Raquel Araujo; Bueno-Junior, Lezio Soares; Kandratavicius, Ludmyla; Peixoto-Santos, José Eduardo; Crippa, José Alexandre; Cecilio Hallak, Jaime Eduardo; Zuardi, Antonio Waldo; Szawka, Raphael Escorsim; Anselmo-Franci, Janete; Leite, João Pereira; Romcy-Pereira, Rodrigo Neves

    2017-05-14

    The prefrontal cortex (PFC), amygdala and hippocampus display a coordinated activity during acquisition of associative fear memories. Evidence indicates that PFC engagement in aversive memory formation does not progress linearly as previously thought. Instead, it seems to be recruited at specific time windows after memory acquisition, which has implications for the treatment of post-traumatic stress disorders. Cannabidiol (CBD), the major non-psychotomimetic phytocannabinoid of the Cannabis sativa plant, is known to modulate contextual fear memory acquisition in rodents. However, it is still not clear how CBD interferes with PFC-dependent processes during post-training memory consolidation. Here, we tested whether intra-PFC infusions of CBD immediately after or 5h following contextual fear conditioning was able to interfere with memory consolidation. Neurochemical and cellular correlates of the CBD treatment were evaluated by the quantification of extracellular levels of dopamine (DA), serotonin, and their metabolites in the PFC and by measuring the cellular expression of activity-dependent transcription factors in cortical and limbic regions. Our results indicate that bilateral intra-PFC CBD infusion impaired contextual fear memory consolidation when applied 5h after conditioning, but had no effect when applied immediately after it. This effect was associated with a reduction in DA turnover in the PFC following retrieval 5days after training. We also observed that post-conditioning infusion of CBD reduced c-fos and zif-268 protein expression in the hippocampus, PFC, and thalamus. Our findings support that CBD interferes with contextual fear memory consolidation by reducing PFC influence on cortico-limbic circuits. Copyright © 2017 IBRO. Published by Elsevier Ltd. All rights reserved.

  19. Discrimination of Bacillus anthracis Spores by Direct in-situ Analysis of Matrix-Assisted Laser Desorption/Ionization Time-Of-Flight Mass Spectrometry

    International Nuclear Information System (INIS)

    Jeong, Youngsu; Lee, Jonghee; Kim, Seongsoo

    2013-01-01

    The rapid and accurate identification of biological agents is a critical step in the case of bio-terror and biological warfare attacks. Recently, matrix-assisted laser desorption/ionization time-of-flight mass spectrometry has been widely used for the identification of microorganisms. In this study, we describe a method for the rapid and accurate discrimination of Bacillus anthracis spores using MALDI-TOF MS. Our direct in-situ analysis of MALDI-TOF MS does not involve subsequent high-resolution mass analyses and sample preparation steps. This method allowed the detection of species-specific biomarkers from each Bacillus spores. Especially, B. anthracis spores had specific biomarker peaks at 2503, 3089, 3376, 6684, 6698, 6753, and 6840 m/z. Cluster and PCA analyses of the mass spectra of Bacillus spores revealed distinctively separated clusters and within-groups similarity. Therefore, we believe that this method is effective in the real-time identification of biological warfare agents such as B. anthracis as well as other microorganisms in the field

  20. Discrimination of Bacillus anthracis Spores by Direct in-situ Analysis of Matrix-Assisted Laser Desorption/Ionization Time-Of-Flight Mass Spectrometry

    Energy Technology Data Exchange (ETDEWEB)

    Jeong, Youngsu; Lee, Jonghee; Kim, Seongsoo [Agency for Defense Development, Daejeon (Korea, Republic of)

    2013-09-15

    The rapid and accurate identification of biological agents is a critical step in the case of bio-terror and biological warfare attacks. Recently, matrix-assisted laser desorption/ionization time-of-flight mass spectrometry has been widely used for the identification of microorganisms. In this study, we describe a method for the rapid and accurate discrimination of Bacillus anthracis spores using MALDI-TOF MS. Our direct in-situ analysis of MALDI-TOF MS does not involve subsequent high-resolution mass analyses and sample preparation steps. This method allowed the detection of species-specific biomarkers from each Bacillus spores. Especially, B. anthracis spores had specific biomarker peaks at 2503, 3089, 3376, 6684, 6698, 6753, and 6840 m/z. Cluster and PCA analyses of the mass spectra of Bacillus spores revealed distinctively separated clusters and within-groups similarity. Therefore, we believe that this method is effective in the real-time identification of biological warfare agents such as B. anthracis as well as other microorganisms in the field.

  1. Pharmacological evidence that both cognitive memory and habit formation contribute to within-session learning of concurrent visual discriminations.

    Science.gov (United States)

    Turchi, Janita; Devan, Bryan; Yin, Pingbo; Sigrist, Emmalynn; Mishkin, Mortimer

    2010-07-01

    The monkey's ability to learn a set of visual discriminations presented concurrently just once a day on successive days (24-h ITI task) is based on habit formation, which is known to rely on a visuo-striatal circuit and to be independent of visuo-rhinal circuits that support one-trial memory. Consistent with this dissociation, we recently reported that performance on the 24-h ITI task is impaired by a striatal-function blocking agent, the dopaminergic antagonist haloperidol, and not by a rhinal-function blocking agent, the muscarinic cholinergic antagonist scopolamine. In the present study, monkeys were trained on a short-ITI form of concurrent visual discrimination learning, one in which a set of stimulus pairs is repeated not only across daily sessions but also several times within each session (in this case, at about 4-min ITIs). Asymptotic discrimination learning rates in the non-drug condition were reduced by half, from approximately 11 trials/pair on the 24-h ITI task to approximately 5 trials/pair on the 4-min ITI task, and this faster learning was impaired by systemic injections of either haloperidol or scopolamine. The results suggest that in the version of concurrent discrimination learning used here, the short ITIs within a session recruit both visuo-rhinal and visuo-striatal circuits, and that the final performance level is driven by both cognitive memory and habit formation working in concert.

  2. Intuitive analog circuit design

    CERN Document Server

    Thompson, Marc

    2013-01-01

    Intuitive Analog Circuit Design outlines ways of thinking about analog circuits and systems that let you develop a feel for what a good, working analog circuit design should be. This book reflects author Marc Thompson's 30 years of experience designing analog and power electronics circuits and teaching graduate-level analog circuit design, and is the ideal reference for anyone who needs a straightforward introduction to the subject. In this book, Dr. Thompson describes intuitive and ""back-of-the-envelope"" techniques for designing and analyzing analog circuits, including transistor amplifi

  3. The circuit designer's companion

    CERN Document Server

    Williams, Tim

    1991-01-01

    The Circuit Designer's Companion covers the theoretical aspects and practices in analogue and digital circuit design. Electronic circuit design involves designing a circuit that will fulfill its specified function and designing the same circuit so that every production model of it will fulfill its specified function, and no other undesired and unspecified function.This book is composed of nine chapters and starts with a review of the concept of grounding, wiring, and printed circuits. The subsequent chapters deal with the passive and active components of circuitry design. These topics are foll

  4. Electronic devices and circuits

    CERN Document Server

    Pridham, Gordon John

    1972-01-01

    Electronic Devices and Circuits, Volume 3 provides a comprehensive account on electronic devices and circuits and includes introductory network theory and physics. The physics of semiconductor devices is described, along with field effect transistors, small-signal equivalent circuits of bipolar transistors, and integrated circuits. Linear and non-linear circuits as well as logic circuits are also considered. This volume is comprised of 12 chapters and begins with an analysis of the use of Laplace transforms for analysis of filter networks, followed by a discussion on the physical properties of

  5. Electronic circuit for control rod attracting electromagnet

    International Nuclear Information System (INIS)

    Ito, Koji.

    1991-01-01

    The present invention provides a discharging circuit for control rod attracting electromagnet used for a reactor which is highly reliable and has high performance. The resistor of the circuit comprises a non-linear resistor element and a blocking rectification element connected in series. The discharging circuit can be prevented from short-circuit by selecting a resistor having a resistance value about ten times as great as the coil resistance, even in a case where the blocking rectification element and the non-linear resistor element are failed. Accordingly, reduction of attracting force and the increase of scream releasing time can be minimized. (I.S.)

  6. A simple neutron-gamma discriminating system

    International Nuclear Information System (INIS)

    Liu Zhongming; Xing Shilin; Wang Zhongmin

    1986-01-01

    A simple neutron-gamma discriminating system is described. A detector and a pulse shape discriminator are suitable for the neutron-gamma discriminating system. The influence of the constant fraction discriminator threshold energy on the neutron-gamma resolution properties is shown. The neutron-gamma timing distributions from an 241 Am-Be source, 2.5 MeV neutron beam and 14 MeV neutron beam are presented

  7. Electrical Circuits and Water Analogies

    Science.gov (United States)

    Smith, Frederick A.; Wilson, Jerry D.

    1974-01-01

    Briefly describes water analogies for electrical circuits and presents plans for the construction of apparatus to demonstrate these analogies. Demonstrations include series circuits, parallel circuits, and capacitors. (GS)

  8. Fully-automated identification of fish species based on otolith contour: using short-time Fourier transform and discriminant analysis (STFT-DA).

    Science.gov (United States)

    Salimi, Nima; Loh, Kar Hoe; Kaur Dhillon, Sarinder; Chong, Ving Ching

    2016-01-01

    Background. Fish species may be identified based on their unique otolith shape or contour. Several pattern recognition methods have been proposed to classify fish species through morphological features of the otolith contours. However, there has been no fully-automated species identification model with the accuracy higher than 80%. The purpose of the current study is to develop a fully-automated model, based on the otolith contours, to identify the fish species with the high classification accuracy. Methods. Images of the right sagittal otoliths of 14 fish species from three families namely Sciaenidae, Ariidae, and Engraulidae were used to develop the proposed identification model. Short-time Fourier transform (STFT) was used, for the first time in the area of otolith shape analysis, to extract important features of the otolith contours. Discriminant Analysis (DA), as a classification technique, was used to train and test the model based on the extracted features. Results. Performance of the model was demonstrated using species from three families separately, as well as all species combined. Overall classification accuracy of the model was greater than 90% for all cases. In addition, effects of STFT variables on the performance of the identification model were explored in this study. Conclusions. Short-time Fourier transform could determine important features of the otolith outlines. The fully-automated model proposed in this study (STFT-DA) could predict species of an unknown specimen with acceptable identification accuracy. The model codes can be accessed at http://mybiodiversityontologies.um.edu.my/Otolith/ and https://peerj.com/preprints/1517/. The current model has flexibility to be used for more species and families in future studies.

  9. Electric circuits essentials

    CERN Document Server

    REA, Editors of

    2012-01-01

    REA's Essentials provide quick and easy access to critical information in a variety of different fields, ranging from the most basic to the most advanced. As its name implies, these concise, comprehensive study guides summarize the essentials of the field covered. Essentials are helpful when preparing for exams, doing homework and will remain a lasting reference source for students, teachers, and professionals. Electric Circuits I includes units, notation, resistive circuits, experimental laws, transient circuits, network theorems, techniques of circuit analysis, sinusoidal analysis, polyph

  10. Intra-individual gait patterns across different time-scales as revealed by means of a supervised learning model using kernel-based discriminant regression.

    Directory of Open Access Journals (Sweden)

    Fabian Horst

    Full Text Available Traditionally, gait analysis has been centered on the idea of average behavior and normality. On one hand, clinical diagnoses and therapeutic interventions typically assume that average gait patterns remain constant over time. On the other hand, it is well known that all our movements are accompanied by a certain amount of variability, which does not allow us to make two identical steps. The purpose of this study was to examine changes in the intra-individual gait patterns across different time-scales (i.e., tens-of-mins, tens-of-hours.Nine healthy subjects performed 15 gait trials at a self-selected speed on 6 sessions within one day (duration between two subsequent sessions from 10 to 90 mins. For each trial, time-continuous ground reaction forces and lower body joint angles were measured. A supervised learning model using a kernel-based discriminant regression was applied for classifying sessions within individual gait patterns.Discernable characteristics of intra-individual gait patterns could be distinguished between repeated sessions by classification rates of 67.8 ± 8.8% and 86.3 ± 7.9% for the six-session-classification of ground reaction forces and lower body joint angles, respectively. Furthermore, the one-on-one-classification showed that increasing classification rates go along with increasing time durations between two sessions and indicate that changes of gait patterns appear at different time-scales.Discernable characteristics between repeated sessions indicate continuous intrinsic changes in intra-individual gait patterns and suggest a predominant role of deterministic processes in human motor control and learning. Natural changes of gait patterns without any externally induced injury or intervention may reflect continuous adaptations of the motor system over several time-scales. Accordingly, the modelling of walking by means of average gait patterns that are assumed to be near constant over time needs to be reconsidered in the

  11. Intra-individual gait patterns across different time-scales as revealed by means of a supervised learning model using kernel-based discriminant regression.

    Science.gov (United States)

    Horst, Fabian; Eekhoff, Alexander; Newell, Karl M; Schöllhorn, Wolfgang I

    2017-01-01

    Traditionally, gait analysis has been centered on the idea of average behavior and normality. On one hand, clinical diagnoses and therapeutic interventions typically assume that average gait patterns remain constant over time. On the other hand, it is well known that all our movements are accompanied by a certain amount of variability, which does not allow us to make two identical steps. The purpose of this study was to examine changes in the intra-individual gait patterns across different time-scales (i.e., tens-of-mins, tens-of-hours). Nine healthy subjects performed 15 gait trials at a self-selected speed on 6 sessions within one day (duration between two subsequent sessions from 10 to 90 mins). For each trial, time-continuous ground reaction forces and lower body joint angles were measured. A supervised learning model using a kernel-based discriminant regression was applied for classifying sessions within individual gait patterns. Discernable characteristics of intra-individual gait patterns could be distinguished between repeated sessions by classification rates of 67.8 ± 8.8% and 86.3 ± 7.9% for the six-session-classification of ground reaction forces and lower body joint angles, respectively. Furthermore, the one-on-one-classification showed that increasing classification rates go along with increasing time durations between two sessions and indicate that changes of gait patterns appear at different time-scales. Discernable characteristics between repeated sessions indicate continuous intrinsic changes in intra-individual gait patterns and suggest a predominant role of deterministic processes in human motor control and learning. Natural changes of gait patterns without any externally induced injury or intervention may reflect continuous adaptations of the motor system over several time-scales. Accordingly, the modelling of walking by means of average gait patterns that are assumed to be near constant over time needs to be reconsidered in the context of

  12. Piezoelectric drive circuit

    Science.gov (United States)

    Treu, C.A. Jr.

    1999-08-31

    A piezoelectric motor drive circuit is provided which utilizes the piezoelectric elements as oscillators and a Meacham half-bridge approach to develop feedback from the motor ground circuit to produce a signal to drive amplifiers to power the motor. The circuit automatically compensates for shifts in harmonic frequency of the piezoelectric elements due to pressure and temperature changes. 7 figs.

  13. Load testing circuit

    DEFF Research Database (Denmark)

    2009-01-01

    A load testing circuit a circuit tests the load impedance of a load connected to an amplifier. The load impedance includes a first terminal and a second terminal, the load testing circuit comprising a signal generator providing a test signal of a defined bandwidth to the first terminal of the load...

  14. Short-circuit logic

    NARCIS (Netherlands)

    Bergstra, J.A.; Ponse, A.

    2010-01-01

    Short-circuit evaluation denotes the semantics of propositional connectives in which the second argument is only evaluated if the first argument does not suffice to determine the value of the expression. In programming, short-circuit evaluation is widely used. A short-circuit logic is a variant of

  15. Discrimination and Anti-discrimination in Denmark

    DEFF Research Database (Denmark)

    Olsen, Tore Vincents

    The purpose of this report is to describe and analyse Danish anti-discrimination legislation and the debate about discrimination in Denmark in order to identify present and future legal challenges. The main focus is the implementation of the EU anti-discrimination directives in Danish law...

  16. Within centre evaluation of hypercalcaemia discriminant

    DEFF Research Database (Denmark)

    Nielsen, Bo Friis; Conradsen, Knut

    1996-01-01

    Diagnostic hypercalcaemia discriminant functions, discriminating between clinically significant and non-significant hypercalcaemia, were tested 5 years after their development in order to evaluate the impact of time on their diagnostic capacity. Two populations, consisting of 257 and 129 patients......). The discriminant functions correctly classified 81 and 80% of the women, respectively (NS) and respectively 75% and 64% of the men (NS) in the first and second recorded populations.......Diagnostic hypercalcaemia discriminant functions, discriminating between clinically significant and non-significant hypercalcaemia, were tested 5 years after their development in order to evaluate the impact of time on their diagnostic capacity. Two populations, consisting of 257 and 129 patients...

  17. Proof of Principle for a Real-Time Pathogen Isolation Media Diagnostic: The Use of Laser-Induced Breakdown Spectroscopy to Discriminate Bacterial Pathogens and Antimicrobial-Resistant Staphylococcus aureus Strains Grown on Blood Agar

    Directory of Open Access Journals (Sweden)

    Rosalie A. Multari

    2013-01-01

    Full Text Available Laser-Induced Breakdown Spectroscopy (LIBS is a rapid, in situ, diagnostic technique in which light emissions from a laser plasma formed on the sample are used for analysis allowing automated analysis results to be available in seconds to minutes. This speed of analysis coupled with little or no sample preparation makes LIBS an attractive detection tool. In this study, it is demonstrated that LIBS can be utilized to discriminate both the bacterial species and strains of bacterial colonies grown on blood agar. A discrimination algorithm was created based on multivariate regression analysis of spectral data. The algorithm was deployed on a simulated LIBS instrument system to demonstrate discrimination capability using 6 species. Genetically altered Staphylococcus aureus strains grown on BA, including isogenic sets that differed only by the acquisition of mutations that increase fusidic acid or vancomycin resistance, were also discriminated. The algorithm successfully identified all thirteen cultures used in this study in a time period of 2 minutes. This work provides proof of principle for a LIBS instrumentation system that could be developed for the rapid discrimination of bacterial species and strains demonstrating relatively minor genomic alterations using data collected directly from pathogen isolation media.

  18. Simple Cell Balance Circuit

    Science.gov (United States)

    Johnson, Steven D.; Byers, Jerry W.; Martin, James A.

    2012-01-01

    A method has been developed for continuous cell voltage balancing for rechargeable batteries (e.g. lithium ion batteries). A resistor divider chain is provided that generates a set of voltages representing the ideal cell voltage (the voltage of each cell should be as if the cells were perfectly balanced). An operational amplifier circuit with an added current buffer stage generates the ideal voltage with a very high degree of accuracy, using the concept of negative feedback. The ideal voltages are each connected to the corresponding cell through a current- limiting resistance. Over time, having the cell connected to the ideal voltage provides a balancing current that moves the cell voltage very close to that ideal level. In effect, it adjusts the current of each cell during charging, discharging, and standby periods to force the cell voltages to be equal to the ideal voltages generated by the resistor divider. The device also includes solid-state switches that disconnect the circuit from the battery so that it will not discharge the battery during storage. This solution requires relatively few parts and is, therefore, of lower cost and of increased reliability due to the fewer failure modes. Additionally, this design uses very little power. A preliminary model predicts a power usage of 0.18 W for an 8-cell battery. This approach is applicable to a wide range of battery capacities and voltages.

  19. A method to reduce the suppression of relevant pulses in pulse weight discriminators

    International Nuclear Information System (INIS)

    Schwartz, P.

    1975-01-01

    The pulse height analyzer is used, for instance, with proportional counters. Pulses are broken down into amplitude ranges in accordance with their maximum amplitudes. In pulse height analyzers with real time analog-digital conversion only one deadtime is needed for the respective range selected. For this purpose, all discriminator thresholds of the amplitude stores connected parallel are actuated as an input pulse arrives. The leading edges of the discriminator signals set the amplitude range flip-flop. Only the flip-flop circuit of the maximum amplitude range reached remains set whilst all the others are erased. The trailing edge of the discriminator signals actuates the evaluation of the information stored by the flip-flop circuit selected. It triggers a pulse extender and resets the flip-flop selected. Therefore, only the amplitude range selected needs a deadtime. The pulse extender in addition reduces the processing time of the analyzer by the output pulse length. The characteristic used for the trailing edge is the backward count of the real time analog-digital converter. (DG/RF) [de

  20. Relative ultrasound energy measurement circuit

    OpenAIRE

    Gustafsson, E.Martin I.; Johansson, Jonny; Delsing, Jerker

    2005-01-01

    A relative ultrasound energy estimation circuit has been designed in a standard 0.35-μm CMOS process, to be a part of a thumb size internet connected wireless ultrasound measurement system. This circuit measures the relative energy between received ultrasound pulses, and presents an output signal that is linear to the received energy. Post-layout simulations indicate 7 bit linearity for 500 mV input signals, 5 μsec startup and stop times, 2.6 mW power consumption during active state. The acti...

  1. Logic circuits from zero forcing.

    Science.gov (United States)

    Burgarth, Daniel; Giovannetti, Vittorio; Hogben, Leslie; Severini, Simone; Young, Michael

    We design logic circuits based on the notion of zero forcing on graphs; each gate of the circuits is a gadget in which zero forcing is performed. We show that such circuits can evaluate every monotone Boolean function. By using two vertices to encode each logical bit, we obtain universal computation. We also highlight a phenomenon of "back forcing" as a property of each function. Such a phenomenon occurs in a circuit when the input of gates which have been already used at a given time step is further modified by a computation actually performed at a later stage. Finally, we show that zero forcing can be also used to implement reversible computation. The model introduced here provides a potentially new tool in the analysis of Boolean functions, with particular attention to monotonicity. Moreover, in the light of applications of zero forcing in quantum mechanics, the link with Boolean functions may suggest a new directions in quantum control theory and in the study of engineered quantum spin systems. It is an open technical problem to verify whether there is a link between zero forcing and computation with contact circuits.

  2. RF Circuit Design in Nanometer CMOS

    NARCIS (Netherlands)

    Nauta, Bram

    2007-01-01

    With CMOS technology entering the nanometer regime, the design of analog and RF circuits is complicated by low supply voltages, very non-linear (and nonquadratic) devices and large 1/f noise. At the same time, circuits are required to operate over increasingly wide bandwidths to implement modern

  3. Worst Asymmetrical Short-Circuit Current

    DEFF Research Database (Denmark)

    Arana Aristi, Iván; Holmstrøm, O; Grastrup, L

    2010-01-01

    In a typical power plant, the production scenario and the short-circuit time were found for the worst asymmetrical short-circuit current. Then, a sensitivity analysis on the missing generator values was realized in order to minimize the uncertainty of the results. Afterward the worst asymmetrical...

  4. Wiring of electronic evaluation circuits

    International Nuclear Information System (INIS)

    Bauer, R.; Svoboda, Z.

    1977-01-01

    The wiring is described of electronic evaluation circuits for the automatic viewing of photographic paper strip negatives on which line tracks with an angular scatter relative to the spectrograph longitudinal axis were recorded during the oblique flight of nuclear particles during exposure in the spectrograph. In coincidence evaluation, the size of the angular scatter eventually requires that evaluation dead time be increased. The equipment consists of minimally two fixed registers and a block of logic circuits whose output is designed such as will allow connection to equipment for recording signals corresponding to the number of tracks on the film. The connection may be implemented using integrated circuits guaranteeing high operating reliability and life. (J.B.)

  5. Vertically Integrated Circuits at Fermilab

    International Nuclear Information System (INIS)

    Deptuch, Grzegorz; Demarteau, Marcel; Hoff, James; Lipton, Ronald; Shenai, Alpana; Trimpl, Marcel; Yarema, Raymond; Zimmerman, Tom

    2009-01-01

    The exploration of the vertically integrated circuits, also commonly known as 3D-IC technology, for applications in radiation detection started at Fermilab in 2006. This paper examines the opportunities that vertical integration offers by looking at various 3D designs that have been completed by Fermilab. The emphasis is on opportunities that are presented by through silicon vias (TSV), wafer and circuit thinning and finally fusion bonding techniques to replace conventional bump bonding. Early work by Fermilab has led to an international consortium for the development of 3D-IC circuits for High Energy Physics. The consortium has submitted over 25 different designs for the Fermilab organized MPW run organized for the first time.

  6. ECCS control circuit

    International Nuclear Information System (INIS)

    Sato, Takashi.

    1986-01-01

    Purpose: To afford a sufficient margin to pressure vibrations upon starting of an automatic depressurization system by dispersing pressure vibration in suppression water due to the opening action of an automatic releaf valve in the automatic depressurization system thereby reducing the dynamic load exerted to the surface of the suppression walls. Constitution: Upon occurrence of loss of coolant accidents, an automatic releaf valve for automatic depressurization is opened to deliver the steams in the pressure vessel into the suppression pool. Since a plurality of automatic releaf valves have usually been disposed, if they are opened simultaneously, excess dynamic loads are exerted due to the pressure vibrations to the wall surface of the suppression pool. In this invention, a control circuit is disposed such that the opening timing for each of the automatic releaf valves is deviated upon occurrence of a driving signal for the automatic depressurization system to thereby disperse the pressure vibrations in the suppression water. (Kamimura, M.)

  7. Inductive circuit arrangements

    International Nuclear Information System (INIS)

    Mansfield, Peter; Coxon, R.J.

    1987-01-01

    A switched coil arrangement is connected in a bridge configuration of four switches S 1 , S 2 , S 3 and S 4 which are each shunted by diodes D 1 , D 2 , D 3 and D 4 so that current can flow in either direction through a coil L depending on the setting of the switches. A capacitor C is connected across the bridge through a switch S 5 to receive the inductive energy stored in coil L on breaking the current flow path through the coil. The electrostatic energy stored in capacitor C can then be used to supply current through the coil in the reverse direction either immediately or after a time delay. Coil L may be a superconductive coil. Losses in the circuit can be made up by a trickle charge of capacitor C from a separate supply V 2 . The device may be used in nuclear magnetic resonance imaging. (author)

  8. Electric circuits and signals

    CERN Document Server

    Sabah, Nassir H

    2007-01-01

    Circuit Variables and Elements Overview Learning Objectives Electric Current Voltage Electric Power and Energy Assigned Positive Directions Active and Passive Circuit Elements Voltage and Current Sources The Resistor The Capacitor The Inductor Concluding Remarks Summary of Main Concepts and Results Learning Outcomes Supplementary Topics on CD Problems and Exercises Basic Circuit Connections and Laws Overview Learning Objectives Circuit Terminology Kirchhoff's Laws Voltage Division and Series Connection of Resistors Current Division and Parallel Connection of Resistors D-Y Transformation Source Equivalence and Transformation Reduced-Voltage Supply Summary of Main Concepts and Results Learning Outcomes Supplementary Topics and Examples on CD Problems and Exercises Basic Analysis of Resistive Circuits Overview Learning Objectives Number of Independent Circuit Equations Node-Voltage Analysis Special Considerations in Node-Voltage Analysis Mesh-Current Analysis Special Conside...

  9. [Shunt and short circuit].

    Science.gov (United States)

    Rangel-Abundis, Alberto

    2006-01-01

    Shunt and short circuit are antonyms. In French, the term shunt has been adopted to denote the alternative pathway of blood flow. However, in French, as well as in Spanish, the word short circuit (court-circuit and cortocircuito) is synonymous with shunt, giving rise to a linguistic and scientific inconsistency. Scientific because shunt and short circuit made reference to a phenomenon that occurs in the field of the physics. Because shunt and short circuit are antonyms, it is necessary to clarify that shunt is an alternative pathway of flow from a net of high resistance to a net of low resistance, maintaining the stream. Short circuit is the interruption of the flow, because a high resistance impeaches the flood. This concept is applied to electrical and cardiovascular physiology, as well as to the metabolic pathways.

  10. Physically based arc-circuit interaction

    International Nuclear Information System (INIS)

    Zhong-Lie, L.

    1984-01-01

    An integral arc model is extended to study the interaction of the gas blast arc with the test circuit in this paper. The deformation in the waveshapes of arc current and voltage around the current zero has been formulated to first approximation by using a simple model of arc voltage based on the arc core energy conservation. By supplementing with the time scale for the radiation, the time rates of arc processes were amended. Both the contributions of various arc processes and the influence of circuit parameters to the arc-circuit interaction have been estimated by this theory. Analysis generated a new method of calculating test circuit parameters which improves the accurate simulation of arc-circuit interaction. The new method agrees with the published experimental results

  11. Discrimination of chromosome by autoradiography

    International Nuclear Information System (INIS)

    Masubuchi, Masanori

    1975-01-01

    This paper describes discrimination of chromosome by autoradiography. In this method, the difference in DNA synthetic phase between each chromosome was used as a standard, and the used chromosome was in metaphase, as morphological characteristics were markedly in this phase. Cell cycle and autoradiography with 3 H-thymidine were also examined. In order to discriminate chromosome by autoradiography, it was effective to utilize the labelled pattern in late DNA synthetic phase, where asynchronous replication of chromosome appeared most obviously. DNA synthesis in chromosome was examined in each DNA synthetic phase by culturing the chromosome after the treatment with 3 H-thymidine and altering the time to prepare chromosome specimen. Discrimination of chromosome in plants and animals by autoradiography was also mentioned. It was noticed as a structural and functional discrimination of chromosome to observe amino acid uptake into chromosome protein and to utilize the difference in labelled pattern between the sites of chromosome. (K. Serizawa)

  12. Egg discrimination in the Australian reed warbler (Acrocephalus australis) : rejection response toward model and conspecific eggs depending on timing and mode of artificial parasitism

    NARCIS (Netherlands)

    Welbergen, J; Komdeur, J; Kats, R; Berg, M

    2001-01-01

    In a coevolutionary arms race between an interspecific brood parasite and its host species, bath are expected to evolve adaptations and counteradaptations. We studied egg discrimination in the Australian warbler (Acrocephalus australis). This species is currently not significantly parasitized by the

  13. Analog circuits cookbook

    CERN Document Server

    Hickman, Ian

    2013-01-01

    Analog Circuits Cookbook presents articles about advanced circuit techniques, components and concepts, useful IC for analog signal processing in the audio range, direct digital synthesis, and ingenious video op-amp. The book also includes articles about amplitude measurements on RF signals, linear optical imager, power supplies and devices, and RF circuits and techniques. Professionals and students of electrical engineering will find the book informative and useful.

  14. Analog circuit design

    CERN Document Server

    Dobkin, Bob

    2012-01-01

    Analog circuit and system design today is more essential than ever before. With the growth of digital systems, wireless communications, complex industrial and automotive systems, designers are being challenged to develop sophisticated analog solutions. This comprehensive source book of circuit design solutions aids engineers with elegant and practical design techniques that focus on common analog challenges. The book's in-depth application examples provide insight into circuit design and application solutions that you can apply in today's demanding designs. <

  15. Regenerative feedback resonant circuit

    Science.gov (United States)

    Jones, A. Mark; Kelly, James F.; McCloy, John S.; McMakin, Douglas L.

    2014-09-02

    A regenerative feedback resonant circuit for measuring a transient response in a loop is disclosed. The circuit includes an amplifier for generating a signal in the loop. The circuit further includes a resonator having a resonant cavity and a material located within the cavity. The signal sent into the resonator produces a resonant frequency. A variation of the resonant frequency due to perturbations in electromagnetic properties of the material is measured.

  16. The monolithic double-threshold discriminator

    International Nuclear Information System (INIS)

    Baturitsky, M.A.; Dvornikov, O.V.

    1999-01-01

    A double-threshold discriminator capable of processing input signals of different duration is described. Simplicity of the discriminator circuitry makes it possible to embody the discriminator in multichannel ICs using microwave bipolar-JFET technology. Time walk is calculated to be less than 0.35 ns for the input ramp signals with rise times 25-100 ns and amplitudes 50 mV-1 V

  17. CMOS circuits manual

    CERN Document Server

    Marston, R M

    1995-01-01

    CMOS Circuits Manual is a user's guide for CMOS. The book emphasizes the practical aspects of CMOS and provides circuits, tables, and graphs to further relate the fundamentals with the applications. The text first discusses the basic principles and characteristics of the CMOS devices. The succeeding chapters detail the types of CMOS IC, including simple inverter, gate and logic ICs and circuits, and complex counters and decoders. The last chapter presents a miscellaneous collection of two dozen useful CMOS circuits. The book will be useful to researchers and professionals who employ CMOS circu

  18. Timergenerator circuits manual

    CERN Document Server

    Marston, R M

    2013-01-01

    Timer/Generator Circuits Manual is an 11-chapter text that deals mainly with waveform generator techniques and circuits. Each chapter starts with an explanation of the basic principles of its subject followed by a wide range of practical circuit designs. This work presents a total of over 300 practical circuits, diagrams, and tables.Chapter 1 outlines the basic principles and the different types of generator. Chapters 2 to 9 deal with a specific type of waveform generator, including sine, square, triangular, sawtooth, and special waveform generators pulse. These chapters also include pulse gen

  19. Electronic devices and circuits

    CERN Document Server

    Pridham, Gordon John

    1968-01-01

    Electronic Devices and Circuits, Volume 1 deals with the design and applications of electronic devices and circuits such as passive components, diodes, triodes and transistors, rectification and power supplies, amplifying circuits, electronic instruments, and oscillators. These topics are supported with introductory network theory and physics. This volume is comprised of nine chapters and begins by explaining the operation of resistive, inductive, and capacitive elements in direct and alternating current circuits. The theory for some of the expressions quoted in later chapters is presented. Th

  20. Maximum Acceleration Recording Circuit

    Science.gov (United States)

    Bozeman, Richard J., Jr.

    1995-01-01

    Coarsely digitized maximum levels recorded in blown fuses. Circuit feeds power to accelerometer and makes nonvolatile record of maximum level to which output of accelerometer rises during measurement interval. In comparison with inertia-type single-preset-trip-point mechanical maximum-acceleration-recording devices, circuit weighs less, occupies less space, and records accelerations within narrower bands of uncertainty. In comparison with prior electronic data-acquisition systems designed for same purpose, circuit simpler, less bulky, consumes less power, costs and analysis of data recorded in magnetic or electronic memory devices. Circuit used, for example, to record accelerations to which commodities subjected during transportation on trucks.

  1. MOS integrated circuit design

    CERN Document Server

    Wolfendale, E

    2013-01-01

    MOS Integral Circuit Design aims to help in the design of integrated circuits, especially large-scale ones, using MOS Technology through teaching of techniques, practical applications, and examples. The book covers topics such as design equation and process parameters; MOS static and dynamic circuits; logic design techniques, system partitioning, and layout techniques. Also featured are computer aids such as logic simulation and mask layout, as well as examples on simple MOS design. The text is recommended for electrical engineers who would like to know how to use MOS for integral circuit desi

  2. Circuits and filters handbook

    CERN Document Server

    Chen, Wai-Kai

    2003-01-01

    A bestseller in its first edition, The Circuits and Filters Handbook has been thoroughly updated to provide the most current, most comprehensive information available in both the classical and emerging fields of circuits and filters, both analog and digital. This edition contains 29 new chapters, with significant additions in the areas of computer-aided design, circuit simulation, VLSI circuits, design automation, and active and digital filters. It will undoubtedly take its place as the engineer's first choice in looking for solutions to problems encountered in the design, analysis, and behavi

  3. Security electronics circuits manual

    CERN Document Server

    MARSTON, R M

    1998-01-01

    Security Electronics Circuits Manual is an invaluable guide for engineers and technicians in the security industry. It will also prove to be a useful guide for students and experimenters, as well as providing experienced amateurs and DIY enthusiasts with numerous ideas to protect their homes, businesses and properties.As with all Ray Marston's Circuits Manuals, the style is easy-to-read and non-mathematical, with the emphasis firmly on practical applications, circuits and design ideas. The ICs and other devices used in the practical circuits are modestly priced and readily available ty

  4. An eight channel low-noise CMOS readout circuit for silicon detectors with on-chip front-end FET

    International Nuclear Information System (INIS)

    Fiorini, C.; Porro, M.

    2006-01-01

    We propose a CMOS readout circuit for the processing of signals from multi-channel silicon detectors to be used in X-ray spectroscopy and γ-ray imaging applications. The circuit is composed by eight channels, each one featuring a low-noise preamplifier, a 6th-order semigaussian shaping amplifier with four selectable peaking times, from 1.8 up to 6 μs, a peak stretcher and a discriminator. The circuit is conceived to be used with silicon detectors with a front-end FET integrated on the detector chips itself, like silicon drift detectors with JFET and pixel detectors with DEPMOS. The integrated time constants used for the shaping are implemented by means of an RC-cell, based on the technique of demagnification of the current flowing in a resistor R by means of the use of current mirrors. The eight analog channels of the chip are multiplexed to a single analog output. A suitable digital section provides self-resetting of each channel and trigger output and is able to set independent thresholds on the analog channels by means of a programmable serial register and 3-bit DACs. The circuit has been realized in the 0.35 μm CMOS AMS technology. In this work, the main features of the circuit are presented along with the experimental results of its characterization

  5. Memristor Circuits and Systems

    KAUST Repository

    Zidan, Mohammed A.

    2015-05-01

    resistive-based memory systems and neural computing. For gateless arrays, we present multiport array structure and readout technique, which for the first time introduces a closed-form solution for the challenging crossbar sneak-paths problem. Moreover, a new adaptive threshold readout methodology is proposed, which employs the memory hierarchy locality property in order to improve the access time to the memristor crossbar. Another fast readout technique based on binary counters is presented for locality-less crossbar systems. On the other hand, for gated arrays, we present new readout technique and circuitry that combines the advantages of the gated and gateless memristor arrays, namely the high-density and low-power consumption. In general, the presented structures and readout methodologies empower much faster and power efficient access to the high-density memristive crossbar, compared to other works presented in the literature. Finally, at the circuit level, we propose novel reactance-less oscillators based on memristor devices, which find promising applications in embedded systems and bio-inspired computing. Altogether, we believe that our contributions to the emerging technology help to push it to the next level, shortening the path towards better futuristic computing systems.

  6. Superconducting flux flow digital circuits

    International Nuclear Information System (INIS)

    Martens, J.S.; Zipperian, T.E.; Hietala, V.M.; Ginley, D.S.; Tigges, C.P.; Phillips, J.M.; Siegal, M.P.

    1993-01-01

    The authors have developed a family of digital logic circuits based on superconducting flux flow transistors that show high speed, reasonable signal levels, large fan-out, and large noise margins. The circuits are made from high-temperature superconductors (HTS) and have been shown to operate at over 90 K. NOR gates have been demonstrated with fan-outs of more than 5 and fully loaded switching times less than a fixture-limited 50 ps. Ring-oscillator data suggest inverter delay times of about 40ps when using a 3-μm linewidths. Simple flip-flops have also been demonstrated showing large noise margins, response times of less than 30 ps, and static power dissipation on the order of 30 nW. Among other uses, this logic family is appropriate as an interface between logic families such as single flux quantum and conventional semiconductor logic

  7. Training on Movement Figure-Ground Discrimination Remediates Low-Level Visual Timing Deficits in the Dorsal Stream, Improving High-Level Cognitive Functioning, Including Attention, Reading Fluency, and Working Memory

    Directory of Open Access Journals (Sweden)

    Teri Lawton

    2017-05-01

    Full Text Available The purpose of this study was to determine whether neurotraining to discriminate a moving test pattern relative to a stationary background, figure-ground discrimination, improves vision and cognitive functioning in dyslexics, as well as typically-developing normal students. We predict that improving the speed and sensitivity of figure-ground movement discrimination (PATH to Reading neurotraining acts to remediate visual timing deficits in the dorsal stream, thereby improving processing speed, reading fluency, and the executive control functions of attention and working memory in both dyslexic and normal students who had PATH neurotraining more than in those students who had no neurotraining. This prediction was evaluated by measuring whether dyslexic and normal students improved on standardized tests of cognitive skills following neurotraining exercises, more than following computer-based guided reading (Raz-Kids (RK. The neurotraining used in this study was visually-based training designed to improve magnocellular function at both low and high levels in the dorsal stream: the input to the executive control networks coding working memory and attention. This approach represents a paradigm shift from the phonologically-based treatment for dyslexia, which concentrates on high-level speech and reading areas. This randomized controlled-validation study was conducted by training the entire second and third grade classrooms (42 students for 30 min twice a week before guided reading. Standardized tests were administered at the beginning and end of 12-weeks of intervention training to evaluate improvements in academic skills. Only movement-discrimination training remediated both low-level visual timing deficits and high-level cognitive functioning, including selective and sustained attention, reading fluency and working memory for both dyslexic and normal students. Remediating visual timing deficits in the dorsal stream revealed the causal role of visual

  8. Training on Movement Figure-Ground Discrimination Remediates Low-Level Visual Timing Deficits in the Dorsal Stream, Improving High-Level Cognitive Functioning, Including Attention, Reading Fluency, and Working Memory.

    Science.gov (United States)

    Lawton, Teri; Shelley-Tremblay, John

    2017-01-01

    The purpose of this study was to determine whether neurotraining to discriminate a moving test pattern relative to a stationary background, figure-ground discrimination, improves vision and cognitive functioning in dyslexics, as well as typically-developing normal students. We predict that improving the speed and sensitivity of figure-ground movement discrimination ( PATH to Reading neurotraining) acts to remediate visual timing deficits in the dorsal stream, thereby improving processing speed, reading fluency, and the executive control functions of attention and working memory in both dyslexic and normal students who had PATH neurotraining more than in those students who had no neurotraining. This prediction was evaluated by measuring whether dyslexic and normal students improved on standardized tests of cognitive skills following neurotraining exercises, more than following computer-based guided reading ( Raz-Kids ( RK )). The neurotraining used in this study was visually-based training designed to improve magnocellular function at both low and high levels in the dorsal stream: the input to the executive control networks coding working memory and attention. This approach represents a paradigm shift from the phonologically-based treatment for dyslexia, which concentrates on high-level speech and reading areas. This randomized controlled-validation study was conducted by training the entire second and third grade classrooms (42 students) for 30 min twice a week before guided reading. Standardized tests were administered at the beginning and end of 12-weeks of intervention training to evaluate improvements in academic skills. Only movement-discrimination training remediated both low-level visual timing deficits and high-level cognitive functioning, including selective and sustained attention, reading fluency and working memory for both dyslexic and normal students. Remediating visual timing deficits in the dorsal stream revealed the causal role of visual movement

  9. Training on Movement Figure-Ground Discrimination Remediates Low-Level Visual Timing Deficits in the Dorsal Stream, Improving High-Level Cognitive Functioning, Including Attention, Reading Fluency, and Working Memory

    Science.gov (United States)

    Lawton, Teri; Shelley-Tremblay, John

    2017-01-01

    The purpose of this study was to determine whether neurotraining to discriminate a moving test pattern relative to a stationary background, figure-ground discrimination, improves vision and cognitive functioning in dyslexics, as well as typically-developing normal students. We predict that improving the speed and sensitivity of figure-ground movement discrimination (PATH to Reading neurotraining) acts to remediate visual timing deficits in the dorsal stream, thereby improving processing speed, reading fluency, and the executive control functions of attention and working memory in both dyslexic and normal students who had PATH neurotraining more than in those students who had no neurotraining. This prediction was evaluated by measuring whether dyslexic and normal students improved on standardized tests of cognitive skills following neurotraining exercises, more than following computer-based guided reading (Raz-Kids (RK)). The neurotraining used in this study was visually-based training designed to improve magnocellular function at both low and high levels in the dorsal stream: the input to the executive control networks coding working memory and attention. This approach represents a paradigm shift from the phonologically-based treatment for dyslexia, which concentrates on high-level speech and reading areas. This randomized controlled-validation study was conducted by training the entire second and third grade classrooms (42 students) for 30 min twice a week before guided reading. Standardized tests were administered at the beginning and end of 12-weeks of intervention training to evaluate improvements in academic skills. Only movement-discrimination training remediated both low-level visual timing deficits and high-level cognitive functioning, including selective and sustained attention, reading fluency and working memory for both dyslexic and normal students. Remediating visual timing deficits in the dorsal stream revealed the causal role of visual movement

  10. Full Digital Short Circuit Protection for Advanced IGBTs

    OpenAIRE

    谷村, 拓哉; 湯浅, 一史; 大村, 一郎

    2011-01-01

    A full digital short circuit protection method for advanced IGBTs has been proposed and experimentally demonstrated for the first time. The method employs combination of digital circuit, the gate charge sense instead of the conventional sense IGBT and analog circuit configuration. Digital protection scheme has significant advantages in thevprotection speed and flexibility.

  11. Circuits on Cylinders

    DEFF Research Database (Denmark)

    Hansen, Kristoffer Arnsfelt; Miltersen, Peter Bro; Vinay, V

    2006-01-01

    We consider the computational power of constant width polynomial size cylindrical circuits and nondeterministic branching programs. We show that every function computed by a Pi2 o MOD o AC0 circuit can also be computed by a constant width polynomial size cylindrical nondeterministic branching pro...

  12. Remote tuning of NMR probe circuits.

    Science.gov (United States)

    Kodibagkar, V D; Conradi, M S

    2000-05-01

    There are many circumstances in which the probe tuning adjustments cannot be located near the rf NMR coil. These may occur in high-temperature NMR, low-temperature NMR, and in the use of magnets with small diameter access bores. We address here circuitry for connecting a fixed-tuned probe circuit by a transmission line to a remotely located tuning network. In particular, the bandwidth over which the probe may be remotely tuned while keeping the losses in the transmission line acceptably low is considered. The results show that for all resonant circuit geometries (series, parallel, series-parallel), overcoupling of the line to the tuned circuit is key to obtaining a large tuning bandwidth. At equivalent extents of overcoupling, all resonant circuit geometries have nearly equal remote tuning bandwidths. Particularly for the case of low-loss transmission line, the tuning bandwidth can be many times the tuned circuit's bandwidth, f(o)/Q. Copyright 2000 Academic Press.

  13. Low cost design of microprocessor EDAC circuit

    International Nuclear Information System (INIS)

    Hao Li; Yu Lixin; Peng Heping; Zhuang Wei

    2015-01-01

    An optimization method of error detection and correction (EDAC) circuit design is proposed. The method involves selecting or constructing EDAC codes of low cost hardware, associated with operation scheduling implementation based on 2-input XOR gates structure, and two actions for reducing hardware cells, which can reduce the delay penalties and area costs of the EDAC circuit effectively. The 32-bit EDAC circuit hardware implementation is selected to make a prototype, based on the 180 nm process. The delay penalties and area costs of the EDAC circuit are evaluated. Results show that the time penalty and area cost of the EDAC circuitries are affected with different parity-check matrices and different hardware implementation for the EDAC codes with the same capability of correction and detection code. This method can be used as a guide for low-cost radiation-hardened microprocessor EDAC circuit design and for more advanced technologies. (paper)

  14. Trigger circuits for the PHENIX electromagnetic calorimeter

    International Nuclear Information System (INIS)

    Frank, S.S.; Britton, C.L. Jr.; Winterberg, A.L.; Young, G.R.

    1997-11-01

    Monolithic and discrete circuits have been developed to provide trigger signals for the PHENIX electromagnetic calorimeter detector. These trigger circuits are deadtimeless and create overlapping 4 by 4 energy sums, a cosmic muon trigger, and a 144 channel energy sum. The front end electronics of the PHENIX system sample the energy and timing channels at each bunch crossing (BC) but it is not known immediately if this data is of interest. The information from the trigger circuits is used to determine if the data collected is of interest and should be digitized and stored or discarded. This paper presents details of the design, issues affecting circuit performance, characterization of prototypes fabricated in 1.2 microm Orbit CMOS, and integration of the circuits into the EMCal electronics system

  15. Preferential alkali metal adduct formation by cis geometrical isomers of dicaffeoylquinic acids allows for efficient discrimination from their trans isomers during ultra-high-performance liquid chromatography/quadrupole time-of-flight mass spectrometry

    CSIR Research Space (South Africa)

    Makola, MM

    2016-03-01

    Full Text Available distinguish between various isomers of flavonoid glycosides, but were able to obtain structural information such as the site of glycosylation on the flavonoid. The metal binding of catechol-containing molecules has also been known for a long time... with serious biological and chemical implications.[34] In mass spectrometry studies, the metal binding/chelation by catechol-containing flavonoids has been noted and used to discriminate between closely related molecules.[35] In the current study...

  16. A minor groove binder probe real-time PCR assay for discrimination between type 2-based vaccines and field strains of canine parvovirus.

    Science.gov (United States)

    Decaro, Nicola; Elia, Gabriella; Desario, Costantina; Roperto, Sante; Martella, Vito; Campolo, Marco; Lorusso, Alessio; Cavalli, Alessandra; Buonavoglia, Canio

    2006-09-01

    A minor groove binder (MGB) probe assay was developed to discriminate between type 2-based vaccines and field strains of canine parvovirus (CPV). Considering that most of the CPV vaccines contain the old type 2, no longer circulating in canine population, two MGB probes specific for CPV-2 and the antigenic variants (types 2a, 2b and 2c), respectively, were labeled with different fluorophores. The MGB probe assay was able to discriminate correctly between the old type and the variants, with a detection limit of 10(1) DNA copies and a good reproducibility. Quantitation of the viral DNA loads was accurate, as demonstrated by comparing the CPV DNA titres to those calculated by means of the TaqMan assay recognising all CPV types. This assay will ensure resolution of most diagnostic problems in dogs showing CPV disease shortly after CPV vaccination, although it does not discriminate between field strains and type 2b-based vaccines, recently licensed to market in some countries.

  17. CMOS analog circuit design

    CERN Document Server

    Allen, Phillip E

    1987-01-01

    This text presents the principles and techniques for designing analog circuits to be implemented in a CMOS technology. The level is appropriate for seniors and graduate students familiar with basic electronics, including biasing, modeling, circuit analysis, and some familiarity with frequency response. Students learn the methodology of analog integrated circuit design through a hierarchically-oriented approach to the subject that provides thorough background and practical guidance for designing CMOS analog circuits, including modeling, simulation, and testing. The authors' vast industrial experience and knowledge is reflected in the circuits, techniques, and principles presented. They even identify the many common pitfalls that lie in the path of the beginning designer--expert advice from veteran designers. The text mixes the academic and practical viewpoints in a treatment that is neither superficial nor overly detailed, providing the perfect balance.

  18. Energy-efficient neuron, synapse and STDP integrated circuits.

    Science.gov (United States)

    Cruz-Albrecht, Jose M; Yung, Michael W; Srinivasa, Narayan

    2012-06-01

    Ultra-low energy biologically-inspired neuron and synapse integrated circuits are presented. The synapse includes a spike timing dependent plasticity (STDP) learning rule circuit. These circuits have been designed, fabricated and tested using a 90 nm CMOS process. Experimental measurements demonstrate proper operation. The neuron and the synapse with STDP circuits have an energy consumption of around 0.4 pJ per spike and synaptic operation respectively.

  19. Handling conditional discrimination

    NARCIS (Netherlands)

    Zliobaite, I.; Kamiran, F.; Calders, T.G.K.

    2011-01-01

    Historical data used for supervised learning may contain discrimination. We study how to train classifiers on such data, so that they are discrimination free with respect to a given sensitive attribute, e.g., gender. Existing techniques that deal with this problem aim at removing all discrimination

  20. The Badness of Discrimination

    DEFF Research Database (Denmark)

    Lippert-Rasmussen, Kasper

    2006-01-01

    . In this paper I address these issues. First, I offer a taxonomy of discrimination. I then argue that discrimination is bad, when it is, because it harms people. Finally, I criticize a rival, disrespect-based account according to which discrimination is bad regardless of whether it causes harm....

  1. Approximate circuits for increased reliability

    Science.gov (United States)

    Hamlet, Jason R.; Mayo, Jackson R.

    2015-08-18

    Embodiments of the invention describe a Boolean circuit having a voter circuit and a plurality of approximate circuits each based, at least in part, on a reference circuit. The approximate circuits are each to generate one or more output signals based on values of received input signals. The voter circuit is to receive the one or more output signals generated by each of the approximate circuits, and is to output one or more signals corresponding to a majority value of the received signals. At least some of the approximate circuits are to generate an output value different than the reference circuit for one or more input signal values; however, for each possible input signal value, the majority values of the one or more output signals generated by the approximate circuits and received by the voter circuit correspond to output signal result values of the reference circuit.

  2. Troubleshooting analog circuits

    CERN Document Server

    Pease, Robert A

    1991-01-01

    Troubleshooting Analog Circuits is a guidebook for solving product or process related problems in analog circuits. The book also provides advice in selecting equipment, preventing problems, and general tips. The coverage of the book includes the philosophy of troubleshooting; the modes of failure of various components; and preventive measures. The text also deals with the active components of analog circuits, including diodes and rectifiers, optically coupled devices, solar cells, and batteries. The book will be of great use to both students and practitioners of electronics engineering. Other

  3. Modern TTL circuits manual

    CERN Document Server

    Marston, R M

    2013-01-01

    Modern TTL Circuits Manual provides an introduction to the basic principles of Transistor-Transistor Logic (TTL). This book outlines the major features of the 74 series of integrated circuits (ICs) and introduces the various sub-groups of the TTL family.Organized into seven chapters, this book begins with an overview of the basics of digital ICs. This text then examines the symbology and mathematics of digital logic. Other chapters consider a variety of topics, including waveform generator circuitry, clocked flip-flop and counter circuits, special counter/dividers, registers, data latches, com

  4. Circuit analysis with Multisim

    CERN Document Server

    Baez-Lopez, David

    2011-01-01

    This book is concerned with circuit simulation using National Instruments Multisim. It focuses on the use and comprehension of the working techniques for electrical and electronic circuit simulation. The first chapters are devoted to basic circuit analysis.It starts by describing in detail how to perform a DC analysis using only resistors and independent and controlled sources. Then, it introduces capacitors and inductors to make a transient analysis. In the case of transient analysis, it is possible to have an initial condition either in the capacitor voltage or in the inductor current, or bo

  5. Optoelectronics circuits manual

    CERN Document Server

    Marston, R M

    2013-01-01

    Optoelectronics Circuits Manual covers the basic principles and characteristics of the best known types of optoelectronic devices, as well as the practical applications of many of these optoelectronic devices. The book describes LED display circuits and LED dot- and bar-graph circuits and discusses the applications of seven-segment displays, light-sensitive devices, optocouplers, and a variety of brightness control techniques. The text also tackles infrared light-beam alarms and multichannel remote control systems. The book provides practical user information and circuitry and illustrations.

  6. 'Speedy' superconducting circuits

    International Nuclear Information System (INIS)

    Holst, T.

    1994-01-01

    The most promising concept for realizing ultra-fast superconducting digital circuits is the Rapid Single Flux Quantum (RSFQ) logic. The basic physical principle behind RSFQ logic, which include the storage and transfer of individual magnetic flux quanta in Superconducting Quantum Interference Devices (SQUIDs), is explained. A Set-Reset flip-flop is used as an example of the implementation of an RSFQ based circuit. Finally, the outlook for high-temperature superconducting materials in connection with RSFQ circuits is discussed in some details. (au)

  7. Development and Application of the Single-Spiral Inductive-Capacitive Resonant Circuit Sensor for Wireless, Real-Time Characterization of Moisture in Sand

    Directory of Open Access Journals (Sweden)

    Andrew J. DeRouin

    2013-01-01

    Full Text Available A wireless, passive embedded sensor was designed and fabricated for monitoring moisture in sand. The sensor, consisted of an inductive-capacitive (LC resonant circuit, was made of a printed spiral inductor embedded inside sand. When exposed to an electromagnetic field, the sensor resonated at a specific frequency dependent on the inductance of the inductor and its parasitic capacitance. Since the permittivity of water was much higher than dry sand, moisture in sample increased the parasitic capacitance, thus decreasing the sensor’s resonant frequency. Therefore, the internal moisture level of the sample could be easily measured through tracking the resonant frequency using a detection coil. The fabrication process of this sensor is much simpler compared to LC sensors that contain both capacitive and inductive elements, giving it an economical advantage. A study was conducted to investigate the drying rate of sand samples of different grain sizes. The experimental data showed a strong correlation with the actual moisture content in the samples. The described sensor technology can be applied for long term monitoring of localized water content inside soils and sands to understand the environmental health in these media, or monitoring moisture levels within concrete supports and road pavement.

  8. Theory of circuit block switch-off

    Directory of Open Access Journals (Sweden)

    S. Henzler

    2004-01-01

    Full Text Available Switching-off unused circuit blocks is a promising approach to supress static leakage currents in ultra deep sub-micron CMOS digital systems. Basic performance parameters of Circuit Block Switch-Off (CBSO schemes are defined and their dependence on basic circuit parameters is estimated. Therefore the design trade-off between strong leakage suppression in idle mode and adequate dynamic performance in active mode can be supported by simple analytic investigations. Additionally, a guideline for the estimation of the minimum time for which a block deactivation is useful is derived.

  9. Device for the track useful signal discrimination during the image scanning form bubble chambers

    International Nuclear Information System (INIS)

    Osipov, E.A.; Uvarov, V.A.

    1976-01-01

    A device for the image processing from the bubble chambers, developed to increase the reliability of the track useful signal discrimination at the image scanning from the background component is described. The device consists of a low-pass filter, repetition and memory circuit and subtraction circuit. Besides a delay line and extra channel consisting of a differentiating circuit in series with the selective shaping circuit are introduced into the device. The output signal of the selective shaping is the controlling signal of the repetition and memory circuit, at the output of which a signal corresponding the background component is formed. The functional diagram of the device operation is presented

  10. LABOR DISCRIMINATION IN BULGARIA

    Directory of Open Access Journals (Sweden)

    Vyara Slavyanska

    2017-03-01

    Full Text Available Labor discrimination is a phenomenon with very serious social and economic consequences, which has increased actuality and importance in Bulgaria nowadays. Because of the high price of discrimination, building effective anti-discrimination legislation occupies a special place in the policy of the European Union. Despite the European directives, the presence of anti-discrimination legislation and the broadly declared anti-discrimination inclinations in our country, these are absolutely not enough for providing environment of equality, with a climate of respect and tolerance to the differences. It turns out that certain groups are definitely victims of labor discrimination. In this connection the present article consecutively identifies these groups, as well as the reasons for their discrimination, underlining the necessity and benefits of the integration of the different.

  11. Analogue circuits simulation

    Energy Technology Data Exchange (ETDEWEB)

    Mendo, C

    1988-09-01

    Most analogue simulators have evolved from SPICE. The history and description of SPICE-like simulators are given. From a mathematical formulation of the electronic circuit the following analysis are possible: DC, AC, transient, noise, distortion, Worst Case and Statistical.

  12. Printed circuit for ATLAS

    CERN Multimedia

    Laurent Guiraud

    1999-01-01

    A printed circuit board made by scientists in the ATLAS collaboration for the transition radiaton tracker (TRT). This will read data produced when a high energy particle crosses the boundary between two materials with different electrical properties.

  13. Magnonic logic circuits

    International Nuclear Information System (INIS)

    Khitun, Alexander; Bao Mingqiang; Wang, Kang L

    2010-01-01

    We describe and analyse possible approaches to magnonic logic circuits and basic elements required for circuit construction. A distinctive feature of the magnonic circuitry is that information is transmitted by spin waves propagating in the magnetic waveguides without the use of electric current. The latter makes it possible to exploit spin wave phenomena for more efficient data transfer and enhanced logic functionality. We describe possible schemes for general computing and special task data processing. The functional throughput of the magnonic logic gates is estimated and compared with the conventional transistor-based approach. Magnonic logic circuits allow scaling down to the deep submicrometre range and THz frequency operation. The scaling is in favour of the magnonic circuits offering a significant functional advantage over the traditional approach. The disadvantages and problems of the spin wave devices are also discussed.

  14. Set of CAMAC modules on the base of large integrated circuits for an accelerator synchronization system

    International Nuclear Information System (INIS)

    Glejbman, Eh.M.; Pilyar, N.V.

    1986-01-01

    Parameters of functional moduli in the CAMAC standard developed for accelerator synchronization system are presented. They comprise BZN-8K and BZ-8K digital delay circuits, timing circuit and pulse selection circuit. In every module 3 large integral circuits of KR 580 VI53 type programmed timer, circuits of the given system bus bar interface with bus bars of crate, circuits of data recording control, 2 peripheric storage devices, circuits of initial regime setting, input and output shapers, circuits of installation and removal of blocking in channels are used

  15. Prototype of the front-end circuit for the GOSSIP (Gas On Slimmed Silicon Pixel) chip in the 0.13 μm CMOS technology

    CERN Document Server

    Gromov, V; van der Graaf, H

    2007-01-01

    The new GOSSIP detector, capable to detect single electrons in gas, has certain advantages with respect silicon (pixel) detectors. It does not require a Si sensor; it has a very low detector parasitic capacitance and a zero bias current at the pixel input. These are attractive features to design a compact, low-noise and low-power integrated input circuit. A prototype of the integrated circuit has been developed in 0.13 μm CMOS technology. It includes a few channels equipped with preamplifier, discriminator and the digital circuit to study the feasibility of the TDC-perpixel concept. The design demonstrates very low input referred noise (60e- RMS) in combination with a fast peaking time (40 ns) and an analog power dissipation as low as 2 μW per channel. Switching activity on the clock bus (up to 100 MHz) in the close vicinity of the pixel input pads does not cause noticeable extra noise.

  16. Color Coding of Circuit Quantities in Introductory Circuit Analysis Instruction

    Science.gov (United States)

    Reisslein, Jana; Johnson, Amy M.; Reisslein, Martin

    2015-01-01

    Learning the analysis of electrical circuits represented by circuit diagrams is often challenging for novice students. An open research question in electrical circuit analysis instruction is whether color coding of the mathematical symbols (variables) that denote electrical quantities can improve circuit analysis learning. The present study…

  17. Project Circuits in a Basic Electric Circuits Course

    Science.gov (United States)

    Becker, James P.; Plumb, Carolyn; Revia, Richard A.

    2014-01-01

    The use of project circuits (a photoplethysmograph circuit and a simple audio amplifier), introduced in a sophomore-level electric circuits course utilizing active learning and inquiry-based methods, is described. The development of the project circuits was initiated to promote enhanced engagement and deeper understanding of course content among…

  18. Electron commutator on integrated circuits

    International Nuclear Information System (INIS)

    Demidenko, V.V.

    1975-01-01

    The scheme and the parameters of an electron 16-channel contactless commutator based entirely on integrated circuits are described. The device consists of a unit of analog keys based on field-controlled metal-insulator-semiconductor (m.i.s.) transistors, operation amplifier comparators controlling these keys, and a level distributor. The distributor is based on a ''matrix'' scheme and comprises two ring-shaped shift registers plugged in series and a decoder base on two-input logical elements I-NE. The principal dynamical parameters of the circuit are as follows: the control signal delay in the distributor. 50 nsec; the total channel switch-over time, 500-600 nsec. The commutator transmits both constant signals and pulses whose duration reaches tens of nsec. The commutator can be used in data acquisition and processing systems, for shaping complicated signals (for example), (otherwise signals), for simultaneous oscillographing of several signals, and so forth [ru

  19. Smart Circuit Breaker Communication Infrastructure

    Directory of Open Access Journals (Sweden)

    Octavian Mihai MACHIDON

    2017-11-01

    Full Text Available The expansion of the Internet of Things has fostered the development of smart technologies in fields such as power transmission and distribution systems (as is the Smart Grid and also in regard to home automation (the Smart Home concept. This paper addresses the network communication infrastructure for a Smart Circuit Breaker system, a novel application at the edge of the two afore-mentioned systems (Smart Grid and Smart Home. Such a communication interface has high requirements from functionality, performance and security point of views, given the large amount of distributed connected elements and the real-time information transmission and system management. The paper describes the design and implementation of the data server, Web interface and the embedded networking capabilities of the smart circuit breakers, underlining the protocols and communication technologies used.

  20. Superconducting quantum circuits theory and application

    OpenAIRE

    Deng, Xiuhao

    2015-01-01

    Superconducting quantum circuit models are widely used to understand superconducting devices. This thesis consists of four studies wherein the superconducting quantum circuit is used to illustrate challenges related to quantum information encoding and processing, quantum simulation, quantum signal detection and amplification.The existence of scalar Aharanov-Bohm phase has been a controversial topic for decades. Scalar AB phase, defined as time integral of electric potential, gives rises to a...

  1. Ribosomal subunit protein typing using matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) for the identification and discrimination of Aspergillus species.

    Science.gov (United States)

    Nakamura, Sayaka; Sato, Hiroaki; Tanaka, Reiko; Kusuya, Yoko; Takahashi, Hiroki; Yaguchi, Takashi

    2017-04-26

    Accurate identification of Aspergillus species is a very important subject. Mass spectral fingerprinting using matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS) is generally employed for the rapid identification of fungal isolates. However, the results are based on simple mass spectral pattern-matching, with no peak assignment and no taxonomic input. We propose here a ribosomal subunit protein (RSP) typing technique using MALDI-TOF MS for the identification and discrimination of Aspergillus species. The results are concluded to be phylogenetic in that they reflect the molecular evolution of housekeeping RSPs. The amino acid sequences of RSPs of genome-sequenced strains of Aspergillus species were first verified and compared to compile a reliable biomarker list for the identification of Aspergillus species. In this process, we revealed that many amino acid sequences of RSPs (about 10-60%, depending on strain) registered in the public protein databases needed to be corrected or newly added. The verified RSPs were allocated to RSP types based on their mass. Peak assignments of RSPs of each sample strain as observed by MALDI-TOF MS were then performed to set RSP type profiles, which were then further processed by means of cluster analysis. The resulting dendrogram based on RSP types showed a relatively good concordance with the tree based on β-tubulin gene sequences. RSP typing was able to further discriminate the strains belonging to Aspergillus section Fumigati. The RSP typing method could be applied to identify Aspergillus species, even for species within section Fumigati. The discrimination power of RSP typing appears to be comparable to conventional β-tubulin gene analysis. This method would therefore be suitable for species identification and discrimination at the strain to species level. Because RSP typing can characterize the strains within section Fumigati, this method has potential as a powerful and reliable tool in

  2. Synchronization circuit for shaping electron beam picosecond pulses

    International Nuclear Information System (INIS)

    Pavlov, Yu.S.; Solov'ev, N.G.; Tomnikov, A.P.

    1985-01-01

    A fast response circuit of modulator trigger pulse synchronization of a deflector of the electron linear accelerator at 13 MeV with the given phase of HF-voltage is described. The circuit is constructed using K500 and K100 integrated emitter-coupled logics circuits. Main parameters of a synchropulse are duration of 20-50 ns, pulse rise time of 1-5 ns, pulse amplitude >=10 V, delay instability of a trigger pulse <=+-0.05 ns. A radiopulse with 3 μs duration, 5 V amplitude and 400 Hz frequency enters the circuit input. The circuit can operate at both pulsed operation and continuous modes

  3. Functional neural circuits that underlie developmental stuttering.

    Directory of Open Access Journals (Sweden)

    Jianping Qiao

    Full Text Available The aim of this study was to identify differences in functional and effective brain connectivity between persons who stutter (PWS and typically developing (TD fluent speakers, and to assess whether those differences can serve as biomarkers to distinguish PWS from TD controls. We acquired resting-state functional magnetic resonance imaging data in 44 PWS and 50 TD controls. We then used Independent Component Analysis (ICA together with Hierarchical Partner Matching (HPM to identify networks of robust, functionally connected brain regions that were highly reproducible across participants, and we assessed whether connectivity differed significantly across diagnostic groups. We then used Granger Causality (GC to study the causal interactions (effective connectivity between the regions that ICA and HPM identified. Finally, we used a kernel support vector machine to assess how well these measures of functional connectivity and granger causality discriminate PWS from TD controls. Functional connectivity was stronger in PWS compared with TD controls in the supplementary motor area (SMA and primary motor cortices, but weaker in inferior frontal cortex (IFG, Broca's area, caudate, putamen, and thalamus. Additionally, causal influences were significantly weaker in PWS from the IFG to SMA, and from the basal ganglia to IFG through the thalamus, compared to TD controls. ICA and GC indices together yielded an accuracy of 92.7% in classifying PWS from TD controls. Our findings suggest the presence of dysfunctional circuits that support speech planning and timing cues for the initiation and execution of motor sequences in PWS. Our high accuracy of classification further suggests that these aberrant brain features may serve as robust biomarkers for PWS.

  4. Functional neural circuits that underlie developmental stuttering.

    Science.gov (United States)

    Qiao, Jianping; Wang, Zhishun; Zhao, Guihu; Huo, Yuankai; Herder, Carl L; Sikora, Chamonix O; Peterson, Bradley S

    2017-01-01

    The aim of this study was to identify differences in functional and effective brain connectivity between persons who stutter (PWS) and typically developing (TD) fluent speakers, and to assess whether those differences can serve as biomarkers to distinguish PWS from TD controls. We acquired resting-state functional magnetic resonance imaging data in 44 PWS and 50 TD controls. We then used Independent Component Analysis (ICA) together with Hierarchical Partner Matching (HPM) to identify networks of robust, functionally connected brain regions that were highly reproducible across participants, and we assessed whether connectivity differed significantly across diagnostic groups. We then used Granger Causality (GC) to study the causal interactions (effective connectivity) between the regions that ICA and HPM identified. Finally, we used a kernel support vector machine to assess how well these measures of functional connectivity and granger causality discriminate PWS from TD controls. Functional connectivity was stronger in PWS compared with TD controls in the supplementary motor area (SMA) and primary motor cortices, but weaker in inferior frontal cortex (IFG, Broca's area), caudate, putamen, and thalamus. Additionally, causal influences were significantly weaker in PWS from the IFG to SMA, and from the basal ganglia to IFG through the thalamus, compared to TD controls. ICA and GC indices together yielded an accuracy of 92.7% in classifying PWS from TD controls. Our findings suggest the presence of dysfunctional circuits that support speech planning and timing cues for the initiation and execution of motor sequences in PWS. Our high accuracy of classification further suggests that these aberrant brain features may serve as robust biomarkers for PWS.

  5. Functional neural circuits that underlie developmental stuttering

    Science.gov (United States)

    Zhao, Guihu; Huo, Yuankai; Herder, Carl L.; Sikora, Chamonix O.; Peterson, Bradley S.

    2017-01-01

    The aim of this study was to identify differences in functional and effective brain connectivity between persons who stutter (PWS) and typically developing (TD) fluent speakers, and to assess whether those differences can serve as biomarkers to distinguish PWS from TD controls. We acquired resting-state functional magnetic resonance imaging data in 44 PWS and 50 TD controls. We then used Independent Component Analysis (ICA) together with Hierarchical Partner Matching (HPM) to identify networks of robust, functionally connected brain regions that were highly reproducible across participants, and we assessed whether connectivity differed significantly across diagnostic groups. We then used Granger Causality (GC) to study the causal interactions (effective connectivity) between the regions that ICA and HPM identified. Finally, we used a kernel support vector machine to assess how well these measures of functional connectivity and granger causality discriminate PWS from TD controls. Functional connectivity was stronger in PWS compared with TD controls in the supplementary motor area (SMA) and primary motor cortices, but weaker in inferior frontal cortex (IFG, Broca’s area), caudate, putamen, and thalamus. Additionally, causal influences were significantly weaker in PWS from the IFG to SMA, and from the basal ganglia to IFG through the thalamus, compared to TD controls. ICA and GC indices together yielded an accuracy of 92.7% in classifying PWS from TD controls. Our findings suggest the presence of dysfunctional circuits that support speech planning and timing cues for the initiation and execution of motor sequences in PWS. Our high accuracy of classification further suggests that these aberrant brain features may serve as robust biomarkers for PWS. PMID:28759567

  6. Model reduction for circuit simulation

    CERN Document Server

    Hinze, Michael; Maten, E Jan W Ter

    2011-01-01

    Simulation based on mathematical models plays a major role in computer aided design of integrated circuits (ICs). Decreasing structure sizes, increasing packing densities and driving frequencies require the use of refined mathematical models, and to take into account secondary, parasitic effects. This leads to very high dimensional problems which nowadays require simulation times too large for the short time-to-market demands in industry. Modern Model Order Reduction (MOR) techniques present a way out of this dilemma in providing surrogate models which keep the main characteristics of the devi

  7. Polysilicon photoconductor for integrated circuits

    Science.gov (United States)

    Hammond, R.B.; Bowman, D.R.

    1989-04-11

    A photoconductive element of polycrystalline silicon is provided with intrinsic response time which does not limit overall circuit response. An undoped polycrystalline silicon layer is deposited by LPCVD to a selected thickness on silicon dioxide. The deposited polycrystalline silicon is then annealed at a selected temperature and for a time effective to obtain crystal sizes effective to produce an enhanced current output. The annealed polycrystalline layer is subsequently exposed and damaged by ion implantation to a damage factor effective to obtain a fast photoconductive response. 6 figs.

  8. Circuit QED with transmon qubits

    Energy Technology Data Exchange (ETDEWEB)

    Wulschner, Karl Friedrich; Puertas, Javier; Baust, Alexander; Eder, Peter; Fischer, Michael; Goetz, Jan; Haeberlein, Max; Schwarz, Manuel; Xie, Edwar; Zhong, Ling; Deppe, Frank; Fedorov, Kirill; Marx, Achim; Menzel, Edwin; Gross, Rudolf [Walther-Meissner-Institut, Bayerische Akademie der Wissenschaften, Garching (Germany); Physik-Department, TU Muenchen, Garching (Germany); Nanosystems Initiative Munich (NIM), Muenchen (Germany); Huebl, Hans [Walther-Meissner-Institut, Bayerische Akademie der Wissenschaften, Garching (Germany); Nanosystems Initiative Munich (NIM), Muenchen (Germany); Weides, Martin [Karlsruhe Institute of Technology (KIT), Karlsruhe (Germany)

    2015-07-01

    Superconducting quantum bits are basic building blocks for circuit QED systems. Applications in the fields of quantum computation and quantum simulation require long coherence times. We have fabricated and characterized superconducting transmon qubits which are designed to operate at a high ratio of Josephson energy and charging energy. Due to their low sensitivity to charge noise transmon qubits show good coherence properties. We couple transmon qubits to coplanar waveguide resonators and coplanar slotline resonators and characterize the devices at mK-temperatures. From the experimental data we derive the qubit-resonator coupling strength, the qubit relaxation time and calibrate the photon number in the resonator via Stark shifts.

  9. Low latency asynchronous interface circuits

    Science.gov (United States)

    Sadowski, Greg

    2017-06-20

    In one form, a logic circuit includes an asynchronous logic circuit, a synchronous logic circuit, and an interface circuit coupled between the asynchronous logic circuit and the synchronous logic circuit. The asynchronous logic circuit has a plurality of asynchronous outputs for providing a corresponding plurality of asynchronous signals. The synchronous logic circuit has a plurality of synchronous inputs corresponding to the plurality of asynchronous outputs, a stretch input for receiving a stretch signal, and a clock output for providing a clock signal. The synchronous logic circuit provides the clock signal as a periodic signal but prolongs a predetermined state of the clock signal while the stretch signal is active. The asynchronous interface detects whether metastability could occur when latching any of the plurality of the asynchronous outputs of the asynchronous logic circuit using said clock signal, and activates the stretch signal while the metastability could occur.

  10. Quantum-state discrimination

    International Nuclear Information System (INIS)

    Roa, Luis; Retamal, Juan Carlos; Saavedra, Carlos

    2002-01-01

    A proposal for a physical implementation of a quantum-state discrimination protocol using an ion in a linear trap is studied, where two nonorthogonal quantum states are codified using two electronic states of the ion. In addition, a protocol is given for discriminating superpositions of nonorthogonal entangled states between ions inside widely separated optical cavities. The discrimination protocol is extended to the case of N linearly independent nonorthogonal quantum states lying in a space of 2N-1 dimensions

  11. Socially-Tolerable Discrimination

    OpenAIRE

    Amegashie, J. Atsu

    2008-01-01

    History is replete with overt discrimination on the basis of race, gender, age, citizenship, ethnicity, marital status, academic performance, health status, volume of market transactions, religion, sexual orientation, etc. However, these forms of discrimination are not equally tolerable. For example, discrimination based on immutable or prohibitively unalterable characteristics such as race, gender, or ethnicity is much less acceptable. Why? I develop a simple rent-seeking model of conflict w...

  12. A deadtime reduction circuit for thermal neutron coincidence counters with Amptek preamplifiers

    International Nuclear Information System (INIS)

    Bourret, S.C.; Krick, M.S.

    1994-01-01

    We have developed a deadtime reduction circuit for thermal neutron coincidence counters using Amptek preamplifier/amplifier/discriminator circuits. The principle is to remove the overlap between the output pulses from the Amptek circuits by adding a derandomizer between the Amptek circuits and the shift-register coincidence electronics. We implemented the derandomizer as an Actel programmable logic array; the derandomizer board is small and can be mounted in the high-voltage junction box with the Amptek circuits, if desired. Up to 32 Amptek circuits can be used with one derandomizer. The derandomizer has seven outputs: four groups of eight inputs, two groups of 16 inputs, and one group of 32 inputs. We selected these groupings to facilitate detector ring-ratio measurements. The circuit was tested with the five-ring research multiplicity counter, which has five output signals-one for each ring. The counter's deadtime was reduced from 70 to 30 ns

  13. Circuit, especially for digital nuclear gyroscope systems

    International Nuclear Information System (INIS)

    Lowdenslager, J.R.

    1974-01-01

    The circuit with at least one or two spin generator shows a digital phase synchronizing loop in solid-state construction without movable mechanical parts. It is stable, may be turned in one direction any number of times without saturation, and also remains phase-synchronized when input signals are turned off. For this purpose, crystal oscillators with certain resonance frequencies are used. The spin generators are coupled at the outled side with filtering, squaring, and differential connections generating control impulses synchronous to the spin generators. Step divider circuits are connected to the oscillators, which act upon flip-flop registers. This is controlled by the filtering, squaring, and differential connections. Furthermore, field proportional control circuits with registers, advancing and delay circuits are provided, the registers being connected at the outlet side with digital adders and subtractors. The digital adder serves inertial-related purposes. (DG) [de

  14. Logic circuits based on molecular spider systems.

    Science.gov (United States)

    Mo, Dandan; Lakin, Matthew R; Stefanovic, Darko

    2016-08-01

    Spatial locality brings the advantages of computation speed-up and sequence reuse to molecular computing. In particular, molecular walkers that undergo localized reactions are of interest for implementing logic computations at the nanoscale. We use molecular spider walkers to implement logic circuits. We develop an extended multi-spider model with a dynamic environment wherein signal transmission is triggered via localized reactions, and use this model to implement three basic gates (AND, OR, NOT) and a cascading mechanism. We develop an algorithm to automatically generate the layout of the circuit. We use a kinetic Monte Carlo algorithm to simulate circuit computations, and we analyze circuit complexity: our design scales linearly with formula size and has a logarithmic time complexity. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  15. Integrated circuit design using design automation

    International Nuclear Information System (INIS)

    Gwyn, C.W.

    1976-09-01

    Although the use of computer aids to develop integrated circuits is relatively new at Sandia, the program has been very successful. The results have verified the utility of the in-house CAD design capability. Custom IC's have been developed in much shorter times than available through semiconductor device manufacturers. In addition, security problems were minimized and a saving was realized in circuit cost. The custom CMOS IC's were designed at less than half the cost of designing with conventional techniques. In addition to the computer aided design, the prototype fabrication and testing capability provided by the semiconductor development laboratory and microelectronics computer network allows the circuits to be fabricated and evaluated before the designs are transferred to the commercial semiconductor manufacturers for production. The Sandia design and prototype fabrication facilities provide the capability of complete custom integrated circuit development entirely within the ERDA laboratories

  16. Multi-qubit circuit quantum electrodynamics

    International Nuclear Information System (INIS)

    Viehmann, Oliver

    2013-01-01

    Circuit QED systems are macroscopic, man-made quantum systems in which superconducting artificial atoms, also called Josephson qubits, interact with a quantized electromagnetic field. These systems have been devised to mimic the physics of elementary quantum optical systems with real atoms in a scalable and more flexible framework. This opens up a variety of possible applications of circuit QED systems. For instance, they provide a promising platform for processing quantum information. Recent years have seen rapid experimental progress on these systems, and experiments with multi-component circuit QED architectures are currently starting to come within reach. In this thesis, circuit QED systems with multiple Josephson qubits are studied theoretically. We focus on simple and experimentally realistic extensions of the currently operated circuit QED setups and pursue investigations in two main directions. First, we consider the equilibrium behavior of circuit QED systems containing a large number of mutually noninteracting Josephson charge qubits. The currently accepted standard description of circuit QED predicts the possibility of superradiant phase transitions in such systems. However, a full microscopic treatment shows that a no-go theorem for superradiant phase transitions known from atomic physics applies to circuit QED systems as well. This reveals previously unknown limitations of the applicability of the standard theory of circuit QED to multi-qubit systems. Second, we explore the potential of circuit QED for quantum simulations of interacting quantum many-body systems. We propose and analyze a circuit QED architecture that implements the quantum Ising chain in a time-dependent transverse magnetic field. Our setup can be used to study quench dynamics, the propagation of localized excitations, and other non-equilibrium features in this paradigmatic model in the theory of non-equilibrium thermodynamics and quantumcritical phenomena. The setup is based on a

  17. Multi-qubit circuit quantum electrodynamics

    Energy Technology Data Exchange (ETDEWEB)

    Viehmann, Oliver

    2013-09-03

    Circuit QED systems are macroscopic, man-made quantum systems in which superconducting artificial atoms, also called Josephson qubits, interact with a quantized electromagnetic field. These systems have been devised to mimic the physics of elementary quantum optical systems with real atoms in a scalable and more flexible framework. This opens up a variety of possible applications of circuit QED systems. For instance, they provide a promising platform for processing quantum information. Recent years have seen rapid experimental progress on these systems, and experiments with multi-component circuit QED architectures are currently starting to come within reach. In this thesis, circuit QED systems with multiple Josephson qubits are studied theoretically. We focus on simple and experimentally realistic extensions of the currently operated circuit QED setups and pursue investigations in two main directions. First, we consider the equilibrium behavior of circuit QED systems containing a large number of mutually noninteracting Josephson charge qubits. The currently accepted standard description of circuit QED predicts the possibility of superradiant phase transitions in such systems. However, a full microscopic treatment shows that a no-go theorem for superradiant phase transitions known from atomic physics applies to circuit QED systems as well. This reveals previously unknown limitations of the applicability of the standard theory of circuit QED to multi-qubit systems. Second, we explore the potential of circuit QED for quantum simulations of interacting quantum many-body systems. We propose and analyze a circuit QED architecture that implements the quantum Ising chain in a time-dependent transverse magnetic field. Our setup can be used to study quench dynamics, the propagation of localized excitations, and other non-equilibrium features in this paradigmatic model in the theory of non-equilibrium thermodynamics and quantumcritical phenomena. The setup is based on a

  18. Junction and circuit fabrication

    International Nuclear Information System (INIS)

    Jackel, L.D.

    1980-01-01

    Great strides have been made in Josephson junction fabrication in the four years since the first IC SQUID meeting. Advances in lithography have allowed the production of devices with planar dimensions as small as a few hundred angstroms. Improved technology has provided ultra-high sensitivity SQUIDS, high-efficiency low-noise mixers, and complex integrated circuits. This review highlights some of the new fabrication procedures. The review consists of three parts. Part 1 is a short summary of the requirements on junctions for various applications. Part 2 reviews intergrated circuit fabrication, including tunnel junction logic circuits made at IBM and Bell Labs, and microbridge radiation sources made at SUNY at Stony Brook. Part 3 describes new junction fabrication techniques, the major emphasis of this review. This part includes a discussion of small oxide-barrier tunnel junctions, semiconductor barrier junctions, and microbridge junctions. Part 3 concludes by considering very fine lithography and limitations to miniaturization. (orig.)

  19. Perceptions of weight discrimination: prevalence and comparison to race and gender discrimination in America.

    Science.gov (United States)

    Puhl, R M; Andreyeva, T; Brownell, K D

    2008-06-01

    Limited data are available on the prevalence and patterns of body weight discrimination from representative samples. This study examined experiences of weight/height discrimination in a nationally representative sample of US adults and compared their prevalence and patterns with discrimination experiences based on race and gender. Data were from the National Survey of Midlife Development in the United States, a 1995-1996 community-based survey of English-speaking adults aged 25-74 (N=2290). Reported experiences of weight/height discrimination included a variety of institutional settings and interpersonal relationships. Multivariate regression analyses were used to predict weight/height discrimination controlling for sociodemographic characteristics and body weight status. The prevalence of weight/height discrimination ranged from 5% among men to 10% among women, but these average percentages obscure the much higher risk of weight discrimination among heavier individuals (40% for adults with body mass index (BMI) of 35 and above). Younger individuals with a higher BMI had a particularly high risk of weight/height discrimination regardless of their race, education and weight status. Women were at greater risk for weight/height discrimination than men, especially women with a BMI of 30-35 who were three times more likely to report weight/height discrimination compared to male peers of a similar weight. Weight/height discrimination is prevalent in American society and is relatively close to reported rates of racial discrimination, particularly among women. Both institutional forms of weight/height discrimination (for example, in employment settings) and interpersonal mistreatment due to weight/height (for example, being called names) were common, and in some cases were even more prevalent than discrimination due to gender and race.

  20. Small circuits for cryptography.

    Energy Technology Data Exchange (ETDEWEB)

    Torgerson, Mark Dolan; Draelos, Timothy John; Schroeppel, Richard Crabtree; Miller, Russell D.; Anderson, William Erik

    2005-10-01

    This report examines a number of hardware circuit design issues associated with implementing certain functions in FPGA and ASIC technologies. Here we show circuit designs for AES and SHA-1 that have an extremely small hardware footprint, yet show reasonably good performance characteristics as compared to the state of the art designs found in the literature. Our AES performance numbers are fueled by an optimized composite field S-box design for the Stratix chipset. Our SHA-1 designs use register packing and feedback functionalities of the Stratix LE, which reduce the logic element usage by as much as 72% as compared to other SHA-1 designs.

  1. Silicon integrated circuit process

    International Nuclear Information System (INIS)

    Lee, Jong Duck

    1985-12-01

    This book introduces the process of silicon integrated circuit. It is composed of seven parts, which are oxidation process, diffusion process, ion implantation process such as ion implantation equipment, damage, annealing and influence on manufacture of integrated circuit and device, chemical vapor deposition process like silicon Epitaxy LPCVD and PECVD, photolithography process, including a sensitizer, spin, harden bake, reflection of light and problems related process, infrared light bake, wet-etch, dry etch, special etch and problems of etching, metal process like metal process like metal-silicon connection, aluminum process, credibility of aluminum and test process.

  2. Primer printed circuit boards

    CERN Document Server

    Argyle, Andrew

    2009-01-01

    Step-by-step instructions for making your own PCBs at home. Making your own printed circuit board (PCB) might seem a daunting task, but once you master the steps, it's easy to attain professional-looking results. Printed circuit boards, which connect chips and other components, are what make almost all modern electronic devices possible. PCBs are made from sheets of fiberglass clad with copper, usually in multiplelayers. Cut a computer motherboard in two, for instance, and you'll often see five or more differently patterned layers. Making boards at home is relatively easy

  3. Silicon integrated circuit process

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Jong Duck

    1985-12-15

    This book introduces the process of silicon integrated circuit. It is composed of seven parts, which are oxidation process, diffusion process, ion implantation process such as ion implantation equipment, damage, annealing and influence on manufacture of integrated circuit and device, chemical vapor deposition process like silicon Epitaxy LPCVD and PECVD, photolithography process, including a sensitizer, spin, harden bake, reflection of light and problems related process, infrared light bake, wet-etch, dry etch, special etch and problems of etching, metal process like metal process like metal-silicon connection, aluminum process, credibility of aluminum and test process.

  4. Circuit design for reliability

    CERN Document Server

    Cao, Yu; Wirth, Gilson

    2015-01-01

    This book presents physical understanding, modeling and simulation, on-chip characterization, layout solutions, and design techniques that are effective to enhance the reliability of various circuit units.  The authors provide readers with techniques for state of the art and future technologies, ranging from technology modeling, fault detection and analysis, circuit hardening, and reliability management. Provides comprehensive review on various reliability mechanisms at sub-45nm nodes; Describes practical modeling and characterization techniques for reliability; Includes thorough presentation of robust design techniques for major VLSI design units; Promotes physical understanding with first-principle simulations.

  5. Electronic circuits fundamentals & applications

    CERN Document Server

    Tooley, Mike

    2015-01-01

    Electronics explained in one volume, using both theoretical and practical applications.New chapter on Raspberry PiCompanion website contains free electronic tools to aid learning for students and a question bank for lecturersPractical investigations and questions within each chapter help reinforce learning Mike Tooley provides all the information required to get to grips with the fundamentals of electronics, detailing the underpinning knowledge necessary to appreciate the operation of a wide range of electronic circuits, including amplifiers, logic circuits, power supplies and oscillators. The

  6. Multimodality imaging and state-of-art GPU technology in discriminating benign from malignant breast lesions on real time decision support system

    International Nuclear Information System (INIS)

    Kostopoulos, S; Glotsos, D; Kalatzis, I; Asvestas, P; Cavouras, D; Sidiropoulos, K; Dimitropoulos, N

    2014-01-01

    The aim of this study was to design a pattern recognition system for assisting the diagnosis of breast lesions, using image information from Ultrasound (US) and Digital Mammography (DM) imaging modalities. State-of-art computer technology was employed based on commercial Graphics Processing Unit (GPU) cards and parallel programming. An experienced radiologist outlined breast lesions on both US and DM images from 59 patients employing a custom designed computer software application. Textural features were extracted from each lesion and were used to design the pattern recognition system. Several classifiers were tested for highest performance in discriminating benign from malignant lesions. Classifiers were also combined into ensemble schemes for further improvement of the system's classification accuracy. Following the pattern recognition system optimization, the final system was designed employing the Probabilistic Neural Network classifier (PNN) on the GPU card (GeForce 580GTX) using CUDA programming framework and C++ programming language. The use of such state-of-art technology renders the system capable of redesigning itself on site once additional verified US and DM data are collected. Mixture of US and DM features optimized performance with over 90% accuracy in correctly classifying the lesions

  7. Circuit for Driving Piezoelectric Transducers

    Science.gov (United States)

    Randall, David P.; Chapsky, Jacob

    2009-01-01

    The figure schematically depicts an oscillator circuit for driving a piezoelectric transducer to excite vibrations in a mechanical structure. The circuit was designed and built to satisfy application-specific requirements to drive a selected one of 16 such transducers at a regulated amplitude and frequency chosen to optimize the amount of work performed by the transducer and to compensate for both (1) temporal variations of the resonance frequency and damping time of each transducer and (2) initially unknown differences among the resonance frequencies and damping times of different transducers. In other words, the circuit is designed to adjust itself to optimize the performance of whichever transducer is selected at any given time. The basic design concept may be adaptable to other applications that involve the use of piezoelectric transducers in ultrasonic cleaners and other apparatuses in which high-frequency mechanical drives are utilized. This circuit includes three resistor-capacitor networks that, together with the selected piezoelectric transducer, constitute a band-pass filter having a peak response at a frequency of about 2 kHz, which is approximately the resonance frequency of the piezoelectric transducers. Gain for generating oscillations is provided by a power hybrid operational amplifier (U1). A junction field-effect transistor (Q1) in combination with a resistor (R4) is used as a voltage-variable resistor to control the magnitude of the oscillation. The voltage-variable resistor is part of a feedback control loop: Part of the output of the oscillator is rectified and filtered for use as a slow negative feedback to the gate of Q1 to keep the output amplitude constant. The response of this control loop is much slower than 2 kHz and, therefore, does not introduce significant distortion of the oscillator output, which is a fairly clean sine wave. The positive AC feedback needed to sustain oscillations is derived from sampling the current through the

  8. INTERSECTIONAL DISCRIMINATION AGAINST CHILDREN

    DEFF Research Database (Denmark)

    Ravnbøl, Camilla Ida

    This paper adds a perspective to existing research on child protection by engaging in a debate on intersectional discrimination and its relationship to child protection. The paper has a twofold objective, (1) to further establish intersectionality as a concept to address discrimination against...... children, and (2) to illustrate the importance of addressing intersectionality within rights-based programmes of child protection....

  9. Discrimination and delusional ideation.

    Science.gov (United States)

    Janssen, I; Hanssen, M; Bak, M; Bijl, R V; de Graaf, R; Vollebergh, W; McKenzie, K; van Os, J

    2003-01-01

    In the UK and The Netherlands, people with high rates of psychosis are chronically exposed to discrimination. To test whether perceived discrimination is associated longitudinally with onset of psychosis. A 3-year prospective study of cohorts with no history of psychosis and differential rates of reported discrimination on the basis of age, gender, disability, appearance, skin colour or ethnicity and sexual orientation was conducted in the Dutch general population (n=4076). The main outcome was onset of psychotic symptoms (delusions and hallucinations). The rate of delusional ideation was 0.5% (n=19) in those who did not report discrimination, 0.9% (n=4) in those who reported discrimination in one domain, and 2.7% (n=3) in those who reported discrimination in more than one domain (exact P=0.027). This association remained after adjustment for possible confounders. No association was found between baseline discrimination and onset of hallucinatory experiences. Perceived discrimination may induce delusional ideation and thus contribute to the high observed rates of psychotic disorder in exposed minority populations.

  10. Discrimination and delusional ideation

    NARCIS (Netherlands)

    Janssen, I.C.M.; Hanssen, M.S.S.; Bak, M.L.F.J.; Bijl, R.V.; Graaf, R. de; Vollebergh, W.A.M.; McKenzie, K.; Os, J. van

    2003-01-01

    Background In the UK and The Netherlands, people with high rates of psychosis are chronically exposed to discrimination. Aims To test whether perceived discrimination is associated longitudinally with onset of psychosis. Method A 3-year prospective study of cohorts with no history of psychosis and

  11. Flash-Type Discrimination

    Science.gov (United States)

    Koshak, William J.

    2010-01-01

    This viewgraph presentation describes the significant progress made in the flash-type discrimination algorithm development. The contents include: 1) Highlights of Progress for GLM-R3 Flash-Type discrimination Algorithm Development; 2) Maximum Group Area (MGA) Data; 3) Retrieval Errors from Simulations; and 4) Preliminary Global-scale Retrieval.

  12. Discrimination against Black Students

    Science.gov (United States)

    Aloud, Ashwaq; Alsulayyim, Maryam

    2016-01-01

    Discrimination is a structured way of abusing people based on racial differences, hence barring them from accessing wealth, political participation and engagement in many spheres of human life. Racism and discrimination are inherently rooted in institutions in the society, the problem has spread across many social segments of the society including…

  13. Digital voltage discriminator

    International Nuclear Information System (INIS)

    Zhou Zhicheng

    1992-01-01

    A digital voltage discriminator is described, which is synthesized by digital comparator and ADC. The threshold is program controllable with high stability. Digital region of confusion is approximately equal to 1.5 LSB. This discriminator has a single channel analyzer function model with channel width of 1.5 LSB

  14. Introduction to integral discriminants

    International Nuclear Information System (INIS)

    Morozov, A.; Shakirov, Sh.

    2009-01-01

    The simplest partition function, associated with homogeneous symmetric forms S of degree r in n variables, is integral discriminant J n|r (S) = ∫e -S(x 1 ,...,x n ) dx 1 ...dx n . Actually, S-dependence remains the same if e -S in the integrand is substituted by arbitrary function f(S), i.e. integral discriminant is a characteristic of the form S itself, and not of the averaging procedure. The aim of the present paper is to calculate J n|r in a number of non-Gaussian cases. Using Ward identities - linear differential equations, satisfied by integral discriminants - we calculate J 2|3 ,J 2|4 ,J 2|5 and J 3|3 . In all these examples, integral discriminant appears to be a generalized hypergeometric function. It depends on several SL(n) invariants of S, with essential singularities controlled by the ordinary algebraic discriminant of S.

  15. Parallel basal ganglia circuits for decision making.

    Science.gov (United States)

    Hikosaka, Okihide; Ghazizadeh, Ali; Griggs, Whitney; Amita, Hidetoshi

    2018-03-01

    The basal ganglia control body movements, mainly, based on their values. Critical for this mechanism is dopamine neurons, which sends unpredicted value signals, mainly, to the striatum. This mechanism enables animals to change their behaviors flexibly, eventually choosing a valuable behavior. However, this may not be the best behavior, because the flexible choice is focused on recent, and, therefore, limited, experiences (i.e., short-term memories). Our old and recent studies suggest that the basal ganglia contain separate circuits that process value signals in a completely different manner. They are insensitive to recent changes in value, yet gradually accumulate the value of each behavior (i.e., movement or object choice). These stable circuits eventually encode values of many behaviors and then retain the value signals for a long time (i.e., long-term memories). They are innervated by a separate group of dopamine neurons that retain value signals, even when no reward is predicted. Importantly, the stable circuits can control motor behaviors (e.g., hand or eye) quickly and precisely, which allows animals to automatically acquire valuable outcomes based on historical life experiences. These behaviors would be called 'skills', which are crucial for survival. The stable circuits are localized in the posterior part of the basal ganglia, separately from the flexible circuits located in the anterior part. To summarize, the flexible and stable circuits in the basal ganglia, working together but independently, enable animals (and humans) to reach valuable goals in various contexts.

  16. ESD analog circuits and design

    CERN Document Server

    Voldman, Steven H

    2014-01-01

    A comprehensive and in-depth review of analog circuit layout, schematic architecture, device, power network and ESD design This book will provide a balanced overview of analog circuit design layout, analog circuit schematic development, architecture of chips, and ESD design.  It will start at an introductory level and will bring the reader right up to the state-of-the-art. Two critical design aspects for analog and power integrated circuits are combined. The first design aspect covers analog circuit design techniques to achieve the desired circuit performance. The second and main aspect pres

  17. Unstable oscillators based hyperchaotic circuit

    DEFF Research Database (Denmark)

    Murali, K.; Tamasevicius, A.; G. Mykolaitis, A.

    1999-01-01

    A simple 4th order hyperchaotic circuit with unstable oscillators is described. The circuit contains two negative impedance converters, two inductors, two capacitors, a linear resistor and a diode. The Lyapunov exponents are presented to confirm hyperchaotic nature of the oscillations in the circ...... in the circuit. The performance of the circuit is investigated by means of numerical integration of appropriate differential equations, PSPICE simulations, and hardware experiment.......A simple 4th order hyperchaotic circuit with unstable oscillators is described. The circuit contains two negative impedance converters, two inductors, two capacitors, a linear resistor and a diode. The Lyapunov exponents are presented to confirm hyperchaotic nature of the oscillations...

  18. The test of VLSI circuits

    Science.gov (United States)

    Baviere, Ph.

    Tests which have proven effective for evaluating VLSI circuits for space applications are described. It is recommended that circuits be examined after each manfacturing step to gain fast feedback on inadequacies in the production system. Data from failure modes which occur during operational lifetimes of circuits also permit redefinition of the manufacturing and quality control process to eliminate the defects identified. Other tests include determination of the operational envelope of the circuits, examination of the circuit response to controlled inputs, and the performance and functional speeds of ROM and RAM memories. Finally, it is desirable that all new circuits be designed with testing in mind.

  19. Electronic Circuit Analysis Language (ECAL)

    Science.gov (United States)

    Chenghang, C.

    1983-03-01

    The computer aided design technique is an important development in computer applications and it is an important component of computer science. The special language for electronic circuit analysis is the foundation of computer aided design or computer aided circuit analysis (abbreviated as CACD and CACA) of simulated circuits. Electronic circuit analysis language (ECAL) is a comparatively simple and easy to use circuit analysis special language which uses the FORTRAN language to carry out the explanatory executions. It is capable of conducting dc analysis, ac analysis, and transient analysis of a circuit. Futhermore, the results of the dc analysis can be used directly as the initial conditions for the ac and transient analyses.

  20. An integrated circuit switch

    Science.gov (United States)

    Bonin, E. L.

    1969-01-01

    Multi-chip integrated circuit switch consists of a GaAs photon-emitting diode in close proximity with S1 phototransistor. A high current gain is obtained when the transistor has a high forward common-emitter current gain.

  1. "Printed-circuit" rectenna

    Science.gov (United States)

    Dickinson, R. M.

    1977-01-01

    Rectifying antenna is less bulky structure for absorbing transmitted microwave power and converting it into electrical current. Printed-circuit approach, using microstrip technology and circularly polarized antenna, makes polarization orientation unimportant and allows much smaller arrays for given performance. Innovation is particularly useful with proposed electric vehicles powered by beam microwaves.

  2. Het onzichtbare circuit

    NARCIS (Netherlands)

    Nauta, Bram

    2013-01-01

    De chip, of geïntegreerde schakeling, heeft in een razend tempo ons leven ingrijpend veranderd. Het lijkt zo vanzelfsprekend dat er weer een nieuwe generatie smartphones, tablets of computers is. Maar dat is het niet. Prof.dr.ir. Bram Nauta, hoogleraar Integrated Circuit Design, laat in zijn rede

  3. Voltage regulating circuit

    NARCIS (Netherlands)

    2005-01-01

    A voltage regulating circuit comprising a rectifier (2) for receiving an AC voltage (Vmains) and for generating a rectified AC voltage (vrec), and a capacitor (3) connected in parallel with said rectified AC voltage for providing a DC voltage (VDC) over a load (5), characterized by a unidirectional

  4. Streaming Reduction Circuit

    NARCIS (Netherlands)

    Gerards, Marco Egbertus Theodorus; Kuper, Jan; Kokkeler, Andre B.J.; Molenkamp, Egbert

    2009-01-01

    Reduction circuits are used to reduce rows of floating point values to single values. Binary floating point operators often have deep pipelines, which may cause hazards when many consecutive rows have to be reduced. We present an algorithm by which any number of consecutive rows of arbitrary lengths

  5. A Magnetic Circuit Demonstration.

    Science.gov (United States)

    Vanderkooy, John; Lowe, June

    1995-01-01

    Presents a demonstration designed to illustrate Faraday's, Ampere's, and Lenz's laws and to reinforce the concepts through the analysis of a two-loop magnetic circuit. Can be made dramatic and challenging for sophisticated students but is suitable for an introductory course in electricity and magnetism. (JRH)

  6. Discriminative Transfer Learning for General Image Restoration

    KAUST Repository

    Xiao, Lei

    2018-04-30

    Recently, several discriminative learning approaches have been proposed for effective image restoration, achieving convincing trade-off between image quality and computational efficiency. However, these methods require separate training for each restoration task (e.g., denoising, deblurring, demosaicing) and problem condition (e.g., noise level of input images). This makes it time-consuming and difficult to encompass all tasks and conditions during training. In this paper, we propose a discriminative transfer learning method that incorporates formal proximal optimization and discriminative learning for general image restoration. The method requires a single-pass discriminative training and allows for reuse across various problems and conditions while achieving an efficiency comparable to previous discriminative approaches. Furthermore, after being trained, our model can be easily transferred to new likelihood terms to solve untrained tasks, or be combined with existing priors to further improve image restoration quality.

  7. Discriminative Transfer Learning for General Image Restoration

    KAUST Repository

    Xiao, Lei; Heide, Felix; Heidrich, Wolfgang; Schö lkopf, Bernhard; Hirsch, Michael

    2018-01-01

    Recently, several discriminative learning approaches have been proposed for effective image restoration, achieving convincing trade-off between image quality and computational efficiency. However, these methods require separate training for each restoration task (e.g., denoising, deblurring, demosaicing) and problem condition (e.g., noise level of input images). This makes it time-consuming and difficult to encompass all tasks and conditions during training. In this paper, we propose a discriminative transfer learning method that incorporates formal proximal optimization and discriminative learning for general image restoration. The method requires a single-pass discriminative training and allows for reuse across various problems and conditions while achieving an efficiency comparable to previous discriminative approaches. Furthermore, after being trained, our model can be easily transferred to new likelihood terms to solve untrained tasks, or be combined with existing priors to further improve image restoration quality.

  8. Sampling and Control Circuit Board for an Inertial Measurement Unit

    Science.gov (United States)

    Chelmins, David T (Inventor); Powis, Richard T., Jr. (Inventor); Sands, Obed (Inventor)

    2016-01-01

    A circuit board that serves as a control and sampling interface to an inertial measurement unit ("IMU") is provided. The circuit board is also configured to interface with a local oscillator and an external trigger pulse. The circuit board is further configured to receive the external trigger pulse from an external source that time aligns the local oscillator and initiates sampling of the inertial measurement device for data at precise time intervals based on pulses from the local oscillator. The sampled data may be synchronized by the circuit board with other sensors of a navigation system via the trigger pulse.

  9. Protection of toroidal field coils using multiple circuits

    International Nuclear Information System (INIS)

    Thome, R.J.; Langton, W.G.; Mann, W.R.; Pillsbury, R.D.; Tarrh, J.M.

    1983-01-01

    The protection of toroidal field (TF) coils using multiple circuits is described. The discharge of a single-circuit TF system is given for purposes of definition. Two-circuit TF systems are analyzed and the results presented analytically and graphically. Induced currents, maximum discharge voltages, and discharge time constants are compared to the single-circuit system. Three-circuit TF systems are analyzed. In addition to induced currents, maximum discharge voltages, and time constants, several different discharge scenarios are included. The impacts of having discharge rates versus final maximum coil temperatures as requirements are examined. The out-of-plane forces which occur in the three-circuit system are analyzed using an approximate model. The analysis of multiplecircuit TF systems is briefly described and results for a Toroidal Fusion Core Experiment (TFCX) scale device are given based on computer analysis. The advantages and disadvantages of using multiple-circuit systems are summarized and discussed. The primary disadvantages of multiple circuits are the increased circuit complexity and potential for out-of-plane forces. These are offset by the substantial reduction in maximum discharge voltages, as well as other design options which become available when using multiple circuits

  10. Control circuits for the 1.3 GeV electron synchrotron

    International Nuclear Information System (INIS)

    Asaoka, S.; Shiino, K.; Yoshioka, M.; Norimura, K.

    1980-01-01

    Following control circuits for the 1.3 GeV electron synchrotron, Institute for Nuclear Study, University of Tokyo, have been designed and constructed. 1. Variable delay circuits for the timing pulse of the synchrotron. 2. An alarm circuit for sputter ion pumps. 3. A sample and hold circuit for digital display and computer control of the beam intensity. This report describes detailes of the circuits and their specificatons. (author)

  11. Computational aspects of feedback in neural circuits.

    Directory of Open Access Journals (Sweden)

    Wolfgang Maass

    2007-01-01

    Full Text Available It has previously been shown that generic cortical microcircuit models can perform complex real-time computations on continuous input streams, provided that these computations can be carried out with a rapidly fading memory. We investigate the computational capability of such circuits in the more realistic case where not only readout neurons, but in addition a few neurons within the circuit, have been trained for specific tasks. This is essentially equivalent to the case where the output of trained readout neurons is fed back into the circuit. We show that this new model overcomes the limitation of a rapidly fading memory. In fact, we prove that in the idealized case without noise it can carry out any conceivable digital or analog computation on time-varying inputs. But even with noise, the resulting computational model can perform a large class of biologically relevant real-time computations that require a nonfading memory. We demonstrate these computational implications of feedback both theoretically, and through computer simulations of detailed cortical microcircuit models that are subject to noise and have complex inherent dynamics. We show that the application of simple learning procedures (such as linear regression or perceptron learning to a few neurons enables such circuits to represent time over behaviorally relevant long time spans, to integrate evidence from incoming spike trains over longer periods of time, and to process new information contained in such spike trains in diverse ways according to the current internal state of the circuit. In particular we show that such generic cortical microcircuits with feedback provide a new model for working memory that is consistent with a large set of biological constraints. Although this article examines primarily the computational role of feedback in circuits of neurons, the mathematical principles on which its analysis is based apply to a variety of dynamical systems. Hence they may also

  12. Coherent defects in superconducting circuits

    International Nuclear Information System (INIS)

    Mueller, Clemens

    2011-01-01

    The interaction of superconducting circuits with additional quantum systems is a topic that has found extensive study in the recent past. In the limit where the added system are incoherent, this is the standard field of decoherence and the system dynamics can be described by a simple master equation. In the other limit however, when the additional parts are coherent, the resulting time-evolution can become more complicated. In this thesis we have investigated the interaction of superconducting circuits with coherent and incoherent two-level defects. We have shown theoretical calculations characterizing this interaction for all relevant parameter regimes. In the weak coupling limit, the interaction can be described in an effective bath picture, where the TLS act as parts of a large, decohering environment. For strong coupling, however, the coherent dynamics of the full coupled system has to be considered. We show the calculations of the coupled time-evolution and again characterize the interaction by an effective decoherence rate. We also used experimental data to characterize the microscopic origin of the defects and the details of their interaction with the circuits. The results obtained by analyzing spectroscopic data allow us to place strong constraint on several microscopic models for the observed TLS. However, these calculations are not yet fully conclusive as to the physical nature of the TLS. We propose additional experiments to fully characterize the interaction part of the Hamiltonian, thus providing the answer to the question of the physical origin of the coupling. Additionally we have developed a method to directly drive individual defect states via virtual excitation of the qubit. This method allows one to directly probe the properties of single TLS and possibly make use of their superior coherence times for quantum information purposes. The last part of this thesis provided a way for a possible implementation of geometric quantum computation in

  13. Discrimination in the workforce: how it impacts a business

    OpenAIRE

    Whitfield, Deidre Raquel

    2014-01-01

    Discrimination, in its best form, is a hard concept to fathom as an employee or ordinary citizen. In the workplace, there are times when discrimination is necessary due to extenuating circumstances that revolve around the form or act of discrimination. It could be conveyed to save a life or avoid future conflict. However, it must be clearly stated as a written law that the act is lawful. When unlawful discrimination occurs, it stages an entirely different tone, as it is mainly ...

  14. Integrated neuron circuit for implementing neuromorphic system with synaptic device

    Science.gov (United States)

    Lee, Jeong-Jun; Park, Jungjin; Kwon, Min-Woo; Hwang, Sungmin; Kim, Hyungjin; Park, Byung-Gook

    2018-02-01

    In this paper, we propose and fabricate Integrate & Fire neuron circuit for implementing neuromorphic system. Overall operation of the circuit is verified by measuring discrete devices and the output characteristics of the circuit. Since the neuron circuit shows asymmetric output characteristic that can drive synaptic device with Spike-Timing-Dependent-Plasticity (STDP) characteristic, the autonomous weight update process is also verified by connecting the synaptic device and the neuron circuit. The timing difference of the pre-neuron and the post-neuron induce autonomous weight change of the synaptic device. Unlike 2-terminal devices, which is frequently used to implement neuromorphic system, proposed scheme of the system enables autonomous weight update and simple configuration by using 4-terminal synapse device and appropriate neuron circuit. Weight update process in the multi-layer neuron-synapse connection ensures implementation of the hardware-based artificial intelligence, based on Spiking-Neural- Network (SNN).

  15. Age discrimination: the new Regulations

    OpenAIRE

    Sprack, John

    2006-01-01

    A summary of the principal changes introduced by the Employment Equality (Age) Regulations 2006 as they came into effect in England and Wales. Extracts from the Regulations follow the commentary. Article by John Sprack (Barrister, part-time Chairman of Employment Tribunals and author of Tottel's Guide to the Age Discrimination Regulations 2006) published in Amicus Curiae – Journal of the Society for Advanced Legal Studies at the Institute of Advanced Legal Studies. The Journal is produced by ...

  16. Pass-transistor asynchronous sequential circuits

    Science.gov (United States)

    Whitaker, Sterling R.; Maki, Gary K.

    1989-01-01

    Design methods for asynchronous sequential pass-transistor circuits, which result in circuits that are hazard- and critical-race-free and which have added degrees of freedom for the input signals, are discussed. The design procedures are straightforward and easy to implement. Two single-transition-time state assignment methods are presented, and hardware bounds for each are established. A surprising result is that the hardware realizations for each next state variable and output variable is identical for a given flow table. Thus, a state machine with N states and M outputs can be constructed using a single layout replicated N + M times.

  17. The LMT circuit and SPICE

    DEFF Research Database (Denmark)

    Lindberg, Erik; Murali, K.; Tamacevicius, Arunas

    2006-01-01

    The state equations of the LMT circuit are modeled as a dedicated analogue computer circuit and solved by means of PSpice. The nonlinear part of the system is studied. Problems with the PSpice program are presented....

  18. Resistor Combinations for Parallel Circuits.

    Science.gov (United States)

    McTernan, James P.

    1978-01-01

    To help simplify both teaching and learning of parallel circuits, a high school electricity/electronics teacher presents and illustrates the use of tables of values for parallel resistive circuits in which total resistances are whole numbers. (MF)

  19. Detecting short circuits during assembly

    Science.gov (United States)

    Deboo, G. J.

    1980-01-01

    Detector circuit identifies shorts between bus bars of electronic equipment being wired. Detector sounds alarm and indicates which planes are shorted. Power and ground bus bars are scanned continuously until short circuit occurs.

  20. BR-5 primary circuit decontamination

    International Nuclear Information System (INIS)

    Efimov, I.A.; Nikulin, M.P.; Smirnov-Averin, A.P.; Tymosh, B.S.; Shereshkov, V.S.

    1976-01-01

    Results and methodology of steam-water and acid decontamination of the primary coolant circuit SBR-5 reactor in 1971 are discussed. Regeneration process in a cold trap of the primary coolant circuit is discussed

  1. Magnetic pulse compression circuits for plasma devices

    Energy Technology Data Exchange (ETDEWEB)

    Georgescu, N; Zoita, V; Presura, R [Inst. of Physics and Technology of Radiation Devices, Bucharest (Romania)

    1997-12-31

    Two magnetic pulse compression circuits (MPCC), for two different plasma devices, are presented. The first is a 20 J/pulse, 3-stage circuit designed to trigger a low pressure discharge. The circuit has 16-18 kV working voltage, and 200 nF in each stage. The saturable inductors are realized with toroidal 25 {mu}m strip-wound cores, made of a Fe-Ni alloy, with 1.5 T saturation induction. The total magnetic volume is around 290 cm{sup 3}. By using a 25 kV/1 A thyratron as a primary switch, the time compression is from 3.5 {mu}s to 450 ns, in a short-circuit load. The second magnetic pulser is a 200 J/pulse circuit, designed to drive a high average power plasma focus soft X-ray source, for X-ray microlithography as the main application. The 3-stage pulser should supply a maximum load current of 100 kA with a rise-time of 250 - 300 ns. The maximum pulse voltage applied on the plasma discharge chamber is around 20 - 25 kV. The three saturable inductors in the circuit are made of toroidal strip-wound cores with METGLAS 2605 CO amorphous alloy as the magnetic material. The total, optimized mass of the magnetic material is 34 kg. The maximum repetition rate is limited at 100 Hz by the thyratron used in the first stage of the circuit, the driver supplying to the load about 20 kW average power. (author). 1 tab., 3 figs., 3 refs.

  2. DMILL circuits. The hardened electronics decuples its performances

    International Nuclear Information System (INIS)

    Anon.

    1998-01-01

    Thanks to the DMILL (mixed logic-linear hardening) technology under development at the CEA, MHS, a French company specialized in the fabrication of integrated circuits now produces hardened electronic circuits ten times more resistant to radiations than its competitors. Outside the initial market (several thousands of circuits for the LHC particle accelerator of Geneva), a broad choice of applications is opened to this technology: national defense, space, civil nuclear and medical engineering, and high temperature applications. Short paper. (J.S.)

  3. Classical Simulation of Intermediate-Size Quantum Circuits

    OpenAIRE

    Chen, Jianxin; Zhang, Fang; Chen, Mingcheng; Huang, Cupjin; Newman, Michael; Shi, Yaoyun

    2018-01-01

    We introduce a distributed classical simulation algorithm for general quantum circuits, and present numerical results for calculating the output probabilities of universal random circuits. We find that we can simulate more qubits to greater depth than previously reported using the cluster supported by the Data Infrastructure and Search Technology Division of the Alibaba Group. For example, computing a single amplitude of an $8\\times 8$ qubit circuit with depth $40$ was previously beyond the r...

  4. Receiver Gain Modulation Circuit

    Science.gov (United States)

    Jones, Hollis; Racette, Paul; Walker, David; Gu, Dazhen

    2011-01-01

    A receiver gain modulation circuit (RGMC) was developed that modulates the power gain of the output of a radiometer receiver with a test signal. As the radiometer receiver switches between calibration noise references, the test signal is mixed with the calibrated noise and thus produces an ensemble set of measurements from which ensemble statistical analysis can be used to extract statistical information about the test signal. The RGMC is an enabling technology of the ensemble detector. As a key component for achieving ensemble detection and analysis, the RGMC has broad aeronautical and space applications. The RGMC can be used to test and develop new calibration algorithms, for example, to detect gain anomalies, and/or correct for slow drifts that affect climate-quality measurements over an accelerated time scale. A generalized approach to analyzing radiometer system designs yields a mathematical treatment of noise reference measurements in calibration algorithms. By treating the measurements from the different noise references as ensemble samples of the receiver state, i.e. receiver gain, a quantitative description of the non-stationary properties of the underlying receiver fluctuations can be derived. Excellent agreement has been obtained between model calculations and radiometric measurements. The mathematical formulation is equivalent to modulating the gain of a stable receiver with an externally generated signal and is the basis for ensemble detection and analysis (EDA). The concept of generating ensemble data sets using an ensemble detector is similar to the ensemble data sets generated as part of ensemble empirical mode decomposition (EEMD) with exception of a key distinguishing factor. EEMD adds noise to the signal under study whereas EDA mixes the signal with calibrated noise. It is mixing with calibrated noise that permits the measurement of temporal-functional variability of uncertainty in the underlying process. The RGMC permits the evaluation of EDA by

  5. Rapid Discrimination for Traditional Complex Herbal Medicines from Different Parts, Collection Time, and Origins Using High-Performance Liquid Chromatography and Near-Infrared Spectral Fingerprints with Aid of Pattern Recognition Methods

    Directory of Open Access Journals (Sweden)

    Haiyan Fu

    2015-01-01

    Full Text Available As an effective method, the fingerprint technique, which emphasized the whole compositions of samples, has already been used in various fields, especially in identifying and assessing the quality of herbal medicines. High-performance liquid chromatography (HPLC and near-infrared (NIR, with their unique characteristics of reliability, versatility, precision, and simple measurement, played an important role among all the fingerprint techniques. In this paper, a supervised pattern recognition method based on PLSDA algorithm by HPLC and NIR has been established to identify the information of Hibiscus mutabilis L. and Berberidis radix, two common kinds of herbal medicines. By comparing component analysis (PCA, linear discriminant analysis (LDA, and particularly partial least squares discriminant analysis (PLSDA with different fingerprint preprocessing of NIR spectra variables, PLSDA model showed perfect functions on the analysis of samples as well as chromatograms. Most important, this pattern recognition method by HPLC and NIR can be used to identify different collection parts, collection time, and different origins or various species belonging to the same genera of herbal medicines which proved to be a promising approach for the identification of complex information of herbal medicines.

  6. A Real-Time PCR Assay to Identify and Discriminate Among Wild-Type and Vaccine Strains of Varicella-Zoster Virus and Herpes Simplex Virus in Clinical Specimens, and Comparison With the Clinical Diagnoses

    Science.gov (United States)

    Harbecke, Ruth; Oxman, Michael N.; Arnold, Beth A.; Ip, Charlotte; Johnson, Gary R.; Levin, Myron J.; Gelb, Lawrence D.; Schmader, Kenneth E.; Straus, Stephen E.; Wang, Hui; Wright, Peter F.; Pachucki, Constance T.; Gershon, Anne A.; Arbeit, Robert D.; Davis, Larry E.; Simberkoff, Michael S.; Weinberg, Adriana; Williams, Heather M.; Cheney, Carol; Petrukhin, Luba; Abraham, Katalin G.; Shaw, Alan; Manoff, Susan; Antonello, Joseph M.; Green, Tina; Wang, Yue; Tan, Charles; Keller, Paul M.

    2014-01-01

    A real-time PCR assay was developed to identify varicella-zoster virus (VZV) and herpes simplex virus (HSV) DNA in clinical specimens from subjects with suspected herpes zoster (HZ; shingles). Three sets of primers and probes were used in separate PCR reactions to detect and discriminate among wild-type VZV (VZV-WT), Oka vaccine strain VZV (VZV-Oka), and HSV DNA, and the reaction for each virus DNA was multiplexed with primers and probe specific for the human β-globin gene to assess specimen adequacy. Discrimination of all VZV-WT strains, including Japanese isolates and the Oka parent strain, from VZV-Oka was based upon a single nucleotide polymorphism at position 106262 in ORF 62, resulting in preferential amplification by the homologous primer pair. The assay was highly sensitive and specific for the target virus DNA, and no cross-reactions were detected with any other infectious agent. With the PCR assay as the gold standard, the sensitivity of virus culture was 53% for VZV and 77% for HSV. There was 92% agreement between the clinical diagnosis of HZ by the Clinical Evaluation Committee and the PCR assay results. PMID:19475609

  7. Short-circuited coil in a solenoid circuit of a pulse magnetic field

    International Nuclear Information System (INIS)

    Kivshik, A.F.; Dubrovin, V.Yu.

    1976-01-01

    A short-circuited coil at the end of a long pulse solenoid attenuates the dissipation field by 3-5 times. A plug-configuration field is set up in the middle portion of the pulse solenoid incorporating the short-circuited coils. Shunting of the coils with the induction current by resistor Rsub(shunt) provides for the adjustment of the plug ratio γ

  8. MOS voltage automatic tuning circuit

    OpenAIRE

    李, 田茂; 中田, 辰則; 松本, 寛樹

    2004-01-01

    Abstract ###Automatic tuning circuit adjusts frequency performance to compensate for the process variation. Phase locked ###loop (PLL) is a suitable oscillator for the integrated circuit. It is a feedback system that compares the input ###phase with the output phase. It can make the output frequency equal to the input frequency. In this paper, PLL ###fomed of MOSFET's is presented.The presented circuit consists of XOR circuit, Low-pass filter and Relaxation ###Oscillator. On PSPICE simulation...

  9. Selected collection of circuit drawings

    International Nuclear Information System (INIS)

    1977-01-01

    The many electronics circuits have been constracted in the Electronics Shop for use in nuclear experiments or other purposes of this Institute. The types of these circuits amount to about 500 items in total since 1968. This report describes the electronics circuit diagrams selected from this collection. The circuit details are not presented in this report, because these are already been published in the other technical reports. (auth.)

  10. Diode, transistor & fet circuits manual

    CERN Document Server

    Marston, R M

    2013-01-01

    Diode, Transistor and FET Circuits Manual is a handbook of circuits based on discrete semiconductor components such as diodes, transistors, and FETS. The book also includes diagrams and practical circuits. The book describes basic and special diode characteristics, heat wave-rectifier circuits, transformers, filter capacitors, and rectifier ratings. The text also presents practical applications of associated devices, for example, zeners, varicaps, photodiodes, or LEDs, as well as it describes bipolar transistor characteristics. The transistor can be used in three basic amplifier configuration

  11. Hybrid Circuit QED with Electrons on Helium

    Science.gov (United States)

    Yang, Ge

    Electrons on helium (eHe) is a 2-dimensional system that forms naturally at the interface between superfluid helium and vacuum. It has the highest measured electron mobility, and long predicted spin coherence time. In this talk, we will first review various quantum computer architecture proposals that take advantage of these exceptional properties. In particular, we describe how electrons on helium can be combined with superconducting microwave circuits to take advantage of the recent progress in the field of circuit quantum electrodynamics (cQED). We will then demonstrate how to reliably trap electrons on these devices hours at a time, at millikelvin temperatures inside a dilution refrigerator. The coupling between the electrons and the microwave resonator exceeds 1 MHz, and can be reproduced from the design geometry using our numerical simulation. Finally, we will present our progress on isolating individual electrons in such circuits, to build single-electron quantum dots with electrons on helium.

  12. High voltage MOSFET switching circuit

    Science.gov (United States)

    McEwan, Thomas E.

    1994-01-01

    The problem of source lead inductance in a MOSFET switching circuit is compensated for by adding an inductor to the gate circuit. The gate circuit inductor produces an inductive spike which counters the source lead inductive drop to produce a rectangular drive voltage waveform at the internal gate-source terminals of the MOSFET.

  13. Set discrimination of quantum states

    International Nuclear Information System (INIS)

    Zhang Shengyu; Ying Mingsheng

    2002-01-01

    We introduce a notion of set discrimination, which is an interesting extension of quantum state discrimination. A state is secretly chosen from a number of quantum states, which are partitioned into some disjoint sets. A set discrimination is required to identify which set the given state belongs to. Several essential problems are addressed in this paper, including the condition of perfect set discrimination, unambiguous set discrimination, and in the latter case, the efficiency of the discrimination. This generalizes some important results on quantum state discrimination in the literature. A combination of state and set discrimination and the efficiency are also studied

  14. Efficient quantum circuits for Szegedy quantum walks

    International Nuclear Information System (INIS)

    Loke, T.; Wang, J.B.

    2017-01-01

    A major advantage in using Szegedy’s formalism over discrete-time and continuous-time quantum walks lies in its ability to define a unitary quantum walk by quantizing a Markov chain on a directed or weighted graph. In this paper, we present a general scheme to construct efficient quantum circuits for Szegedy quantum walks that correspond to classical Markov chains possessing transformational symmetry in the columns of the transition matrix. In particular, the transformational symmetry criteria do not necessarily depend on the sparsity of the transition matrix, so this scheme can be applied to non-sparse Markov chains. Two classes of Markov chains that are amenable to this construction are cyclic permutations and complete bipartite graphs, for which we provide explicit efficient quantum circuit implementations. We also prove that our scheme can be applied to Markov chains formed by a tensor product. We also briefly discuss the implementation of Markov chains based on weighted interdependent networks. In addition, we apply this scheme to construct efficient quantum circuits simulating the Szegedy walks used in the quantum Pagerank algorithm for some classes of non-trivial graphs, providing a necessary tool for experimental demonstration of the quantum Pagerank algorithm. - Highlights: • A general theoretical framework for implementing Szegedy walks using quantum circuits. • Explicit efficient quantum circuit implementation of the Szegedy walk for several classes of graphs. • Efficient implementation of Szegedy walks for quantum page-ranking of a certain class of graphs.

  15. Neuronal discrimination capacity

    International Nuclear Information System (INIS)

    Deng Yingchun; Williams, Peter; Feng Jianfeng; Liu Feng

    2003-01-01

    We explore neuronal mechanisms of discriminating between masked signals. It is found that when the correlation between input signals is zero, the output signals are separable if and only if input signals are separable. With positively (negatively) correlated signals, the output signals are separable (mixed) even when input signals are mixed (separable). Exact values of discrimination capacity are obtained for two most interesting cases: the exactly balanced inhibitory and excitatory input case and the uncorrelated input case. Interestingly, the discrimination capacity obtained in these cases is independent of model parameters, input distribution and is universal. Our results also suggest a functional role of inhibitory inputs and correlated inputs or, more generally, the large variability of efferent spike trains observed in in vivo experiments: the larger the variability of efferent spike trains, the easier it is to discriminate between masked input signals

  16. Neuronal discrimination capacity

    Energy Technology Data Exchange (ETDEWEB)

    Deng Yingchun [Department of Mathematics, Hunan Normal University 410081, Changsha (China); COGS, University of Sussex at Brighton, BN1 9QH (United Kingdom); Williams, Peter; Feng Jianfeng [COGS, University of Sussex at Brighton, BN1 9QH (United Kingdom); Liu Feng [COGS, University of Sussex at Brighton, BN1 9QH (United Kingdom); Physics Department, Nanjing University (China)

    2003-12-19

    We explore neuronal mechanisms of discriminating between masked signals. It is found that when the correlation between input signals is zero, the output signals are separable if and only if input signals are separable. With positively (negatively) correlated signals, the output signals are separable (mixed) even when input signals are mixed (separable). Exact values of discrimination capacity are obtained for two most interesting cases: the exactly balanced inhibitory and excitatory input case and the uncorrelated input case. Interestingly, the discrimination capacity obtained in these cases is independent of model parameters, input distribution and is universal. Our results also suggest a functional role of inhibitory inputs and correlated inputs or, more generally, the large variability of efferent spike trains observed in in vivo experiments: the larger the variability of efferent spike trains, the easier it is to discriminate between masked input signals.

  17. Discriminator based on voltage comparator for nuclear physics research

    International Nuclear Information System (INIS)

    Vorob'ev, V.A.; Kiselev, A.A.; Kuz'min, R.N.

    1985-01-01

    This paper describes a simple discriminator of low-level pulses with integral discrimination based on a K521SA3 comparator. The discriminator can be used to record pulses with durations of ≥ 0.1 usec and amplitudes of ≥ 1 mV. the input-pulse amplitude must not exceed the supply-voltage amplitude. A schematic diagram of the discriminator is given. For operation of the NGR spectrometer in the constant-velocity mode, the comparator was gated by the bipolar vibrator-velocity signal. The described circuit is reliable under laboratory conditions and its use is promising in multi-input systems such as those with multisection coordinate detectors

  18. The elusive memristor: properties of basic electrical circuits

    International Nuclear Information System (INIS)

    Joglekar, Yogesh N; Wolf, Stephen J

    2009-01-01

    We present an introduction to and a tutorial on the properties of the recently discovered ideal circuit element, a memristor. By definition, a memristor M relates the charge q and the magnetic flux φ in a circuit and complements a resistor R, a capacitor C and an inductor L as an ingredient of ideal electrical circuits. The properties of these three elements and their circuits are a part of the standard curricula. The existence of the memristor as the fourth ideal circuit element was predicted in 1971 based on symmetry arguments, but was clearly experimentally demonstrated just last year. We present the properties of a single memristor, memristors in series and parallel, as well as ideal memristor-capacitor (MC), memristor-inductor (ML) and memristor-capacitor-inductor (MCL) circuits. We find that the memristor has hysteretic current-voltage characteristics. We show that the ideal MC (ML) circuit undergoes non-exponential charge (current) decay with two time scales and that by switching the polarity of the capacitor, an ideal MCL circuit can be tuned from overdamped to underdamped. We present simple models which show that these unusual properties are closely related to the memristor's internal dynamics. This tutorial complements the pedagogy of ideal circuit elements (R, C and L) and the properties of their circuits, and is aimed at undergraduate physics and electrical engineering students

  19. The elusive memristor: properties of basic electrical circuits

    Energy Technology Data Exchange (ETDEWEB)

    Joglekar, Yogesh N; Wolf, Stephen J [Department of Physics, Indiana University Purdue University Indianapolis, Indianapolis, IN 46202 (United States)], E-mail: yojoglek@iupui.edu

    2009-07-15

    We present an introduction to and a tutorial on the properties of the recently discovered ideal circuit element, a memristor. By definition, a memristor M relates the charge q and the magnetic flux {phi} in a circuit and complements a resistor R, a capacitor C and an inductor L as an ingredient of ideal electrical circuits. The properties of these three elements and their circuits are a part of the standard curricula. The existence of the memristor as the fourth ideal circuit element was predicted in 1971 based on symmetry arguments, but was clearly experimentally demonstrated just last year. We present the properties of a single memristor, memristors in series and parallel, as well as ideal memristor-capacitor (MC), memristor-inductor (ML) and memristor-capacitor-inductor (MCL) circuits. We find that the memristor has hysteretic current-voltage characteristics. We show that the ideal MC (ML) circuit undergoes non-exponential charge (current) decay with two time scales and that by switching the polarity of the capacitor, an ideal MCL circuit can be tuned from overdamped to underdamped. We present simple models which show that these unusual properties are closely related to the memristor's internal dynamics. This tutorial complements the pedagogy of ideal circuit elements (R, C and L) and the properties of their circuits, and is aimed at undergraduate physics and electrical engineering students.

  20. Discrimination in Textbooks

    OpenAIRE

    大津, 尚志

    1996-01-01

    In this paper, I deal with the issues which concern discriminations in textbooks.In America, they have paid special attentions to these problems since 1960's. They made guidelines for textbooks to check various kinds of discriminative descriptions and tried to make textbooks to meet these standards. In this respects I would examine the present states about textbooks in America and would compare them to the Japanese ones. That would be useful, I believe, when we consider these issues in Japan.