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  1. Student Time Usage during Fall Reading Week

    Science.gov (United States)

    Cramer, Ken; Pschibul, Rebecca

    2017-01-01

    The present study investigated the time usage and levels of perceived stress, academic workload, and recreation time for 177 students at the University of Windsor before, during, and after Fall Reading Week (FRW). Over a three-week span (at various times of the day), students received a message to their smartphone to complete a 20-second survey…

  2. A radiotherapeutic clinical trial of twice per week vs. five times per week in oral cancer

    International Nuclear Information System (INIS)

    Handa, K.; Edoliya, T.N.; Pandey, R.P.; Agarwal, Y.C.; Sinha, N.

    1980-01-01

    135 cases of oral cancer have been treated by two fractions per week, and the results are compared with 115 approximately identical cases treated by conventional five days a week schedule with other parameters being identical. Radical irradiation was done by 6000 to 6500 rd in 6-6 1/2 weeks (NSD 1800-1900 ret) and palliative dose was 4500 R4 weeks (NSD 1532 ret). Tumour regression was found markedly superior by conventional regime in radically irradiated cases but much less superior for palliative treatment. Acute and late reaction as well as tumour control at 1 year was better with daily treatment, more so in cases treated for radical cure, while in palliative treatment, the superiority of daily regime was less marked. Our study provides evidence that only for palliation in advanced cases, radiation therapy by 2 fractions a week can be alternatively used. (orig.) [de

  3. Building School Culture One Week at a Time

    Science.gov (United States)

    Zoul, Jeffrey

    2010-01-01

    Use Friday Focus memos to motivate and engage your staff every week, and help create a school culture focused on the growth of students "and" teachers. Easy to understand and implement, Friday Focus memos offer an effective and efficient way to improve student learning, staff development, and school culture from within. Written by educational…

  4. Time-Dependent Kinetics of Tretinoin in Chronic Myelogenous Leukaemia during Intermittent Dose Scheduling: 1 Week On/1 Week Off.

    Science.gov (United States)

    Regazzi, M B; Russo, D; Iacona, I; Sacchi, S; Visani, G; Lazzarino, M; Avvisati, G; Pelicci, P G; Dastoli, G; Grandi, C; Spreafico, S; Grattoni, R; Galieni, P; Rupoli, S; Maiolo, A M; Guerra, E; Liberati, A M

    1998-01-01

    This study investigated the pharmacokinetics of tretinoin during alternating cycles of 1 week of tretinoin treatment and 1 week drug-free in patients with Ph1+ chronic myelogenous leukaemia (CML) in the chronic phase. Eighteen patients with CML were treated with tretinoin 80 mg/m(2)/day (in two divided doses) for 7 consecutive days every other week (one cycle = 1 week on/1 week off). Body systemic exposure to tretinoin as determined by the area under the plasma concentration-time curve (AUC) decreased significantly during the first week of drug administration, from (mean +/- SD) 678.3 +/- 498.1 to 258.7 +/- 272.4 microg/L.h. In about 40% of the patients the decline in plasma concentrations was >/=80%, while 17% of the population did not experience any decline. On day 7 of cycle 1, the mean apparent oral clearance (CL/F) was 2.6 times the corresponding value on day 1. After 1 week without tretinoin, the mean AUC on day 1 of cycle 2 was lower (down 15%) but not statistically different from the corresponding value observed on day 1 of cycle 1; 62% of patients showed an increase in the AUC, which was 40% higher than the corresponding value on day 7 of cycle 1. On day 1 of cycle 6, the AUC and CL/F of tretinoin during a dosage interval were not statistically different from those observed on day 1 of cycle 1 and cycle 2. On all occasions the peak plasma concentration (C(max)) was strongly correlated to the corresponding AUC. No significant change in the time to observed C(max) (t(max)) and in the elimination half-life (t((1/2))) was observed during the whole study. These results confirmed that the metabolism of tretinoin is rapidly up-regulated in CML patients, with significant declines in plasma drug exposure during the first week of drug administration. After tretinoin was discontinued, a return to the noninduced state followed a mean time-cycle similar to the induction. The strong decrease in the apparent oral drug clearance and the absence of significant variations

  5. Factors Influencing Amount of Weekly Exercise Time in Colorectal Cancer Survivors.

    Science.gov (United States)

    Chou, Yun-Jen; Lai, Yeur-Hur; Lin, Been-Ren; Liang, Jin-Tung; Shun, Shiow-Ching

    Performing regular exercise of at least 150 minutes weekly has benefits for colorectal cancer survivors. However, barriers inhibit these survivors from performing regular exercise. The aim of this study was to explore exercise behaviors and significant factors influencing weekly exercise time of more than 150 minutes in colorectal cancer survivors. A cross-sectional study design was used to recruit participants in Taiwan. Guided by the ecological model of health behavior, exercise barriers were assessed including intrapersonal, interpersonal, and environment-related barriers. A multiple logistic regression was used to explore the factors associated with the amount of weekly exercise. Among 321 survivors, 57.0% of them had weekly exercise times of more than 150 minutes. The results identified multiple levels of significant factors related to weekly exercise times including intrapersonal factors (occupational status, functional status, pain, interest in exercise, and beliefs about the importance of exercise) and exercise barriers related to environmental factors (lack of time and bad weather). No interpersonal factors were found to be significant. Colorectal cancer survivors experienced low levels of physical and psychological distress. Multiple levels of significant factors related to exercise time including intrapersonal factors as well as exercise barriers related to environmental factors should be considered. Healthcare providers should discuss with their patients how to perform exercise programs; the discussion should address multiple levels of the ecological model such as any pain problems, functional status, employment status, and time limitations, as well as community environment.

  6. Weekly Trends in Preschoolers’ Physical Activity and Sedentary Time in Childcare

    Directory of Open Access Journals (Sweden)

    Leigh M. Vanderloo

    2015-02-01

    Full Text Available This study sought to examine how the physical activity levels and sedentary time of preschoolers attending center-based childcare varied across the week. Sex differences were also explored. Participants (n = 101 wore Actical™ accelerometers (15 s epoch for five consecutive days during childcare hours only. A multivariate repeated measures analysis of variance was used to evaluate levels of sedentary, light, and moderate-to-vigorous (MVPA physical activity across the five weekdays. Total physical activity (TPA was analyzed separately in a univariate repeated measures ANOVA. Sex was entered as an additional between-subjects factor. Levels of sedentary time, LPA, and TPA across the week were found to be statistically significant, and can best be described by quadratic effects. Participants’ activity levels and sedentary time typically peaked mid-week. Levels of physical activity and sedentary time were not found to significantly differ based on sex. Childcare centers may benefit from the introduction and/or modification of active play-based programming and curricula, particularly at the start and end of the week where preschoolers’ activity levels tend to be lower. Additional investigations are required to confirm these findings.

  7. Feasibility of Incremental 2-Times Weekly Hemodialysis in Incident Patients With Residual Kidney Function

    Directory of Open Access Journals (Sweden)

    Andrew I. Chin

    2017-09-01

    Discussion: More than 50% of incident HD patients with RKF have adequate kidney urea clearance to be considered for 2-times weekly HD. When additionally ultrafiltration volume and blood pressure stability are taken into account, more than one-fourth of the total cohort could optimally start HD in an incremental fashion.

  8. Weekly Time Course of Neuro-Muscular Adaptation to Intensive Strength Training.

    Science.gov (United States)

    Brown, Niklas; Bubeck, Dieter; Haeufle, Daniel F B; Weickenmeier, Johannes; Kuhl, Ellen; Alt, Wilfried; Schmitt, Syn

    2017-01-01

    Detailed description of the time course of muscular adaptation is rarely found in literature. Thus, models of muscular adaptation are difficult to validate since no detailed data of adaptation are available. In this article, as an initial step toward a detailed description and analysis of muscular adaptation, we provide a case report of 8 weeks of intense strength training with two active, male participants. Muscular adaptations were analyzed on a morphological level with MRI scans of the right quadriceps muscle and the calculation of muscle volume, on a voluntary strength level by isometric voluntary contractions with doublet stimulation (interpolated twitch technique) and on a non-voluntary level by resting twitch torques. Further, training volume and isokinetic power were closely monitored during the training phase. Data were analyzed weekly for 1 week prior to training, pre-training, 8 weeks of training and 2 weeks of detraining (no strength training). Results show a very individual adaptation to the intense strength training protocol. While training volume and isokinetic power increased linearly during the training phase, resting twitch parameters decreased for both participants after the first week of training and stayed below baseline until de-training. Voluntary activation level showed an increase in the first 4 weeks of training, while maximum voluntary contraction showed only little increase compared to baseline. Muscle volume increased for both subjects. Especially training status seemed to influence the acute reaction to intense strength training. Fatigue had a major influence on performance and could only be overcome by one participant. The results give a first detailed insight into muscular adaptation to intense strength training on various levels, providing a basis of data for a validation of muscle fatigue and adaptation models.

  9. A comparison of twice-weekly MPD-PUVA and three times-weekly skin typing-PUVA regimens for the treatment of psoriasis

    Energy Technology Data Exchange (ETDEWEB)

    Buckley, D.A.; Rogers, S. [City of Dublin Skin and Cancer Hospital, Dublin (Ireland); Healy, E. [Royal Victoria Infirmary, Newcastle upon Tyne (United Kingdom)

    1995-09-01

    The most frequent PUVA treatment regimen in current use is three times weekly, using skin typing to estimate the starting dose. Recently, it was suggested that twice-weekly treatment, using the minimal phototoxic dose- (MPD) to calculate suberythmal starting doses of UVA, achieved similar clearance rates with fewer treatments and a lower cumulative UVA dose. We have carried out a trial on 83 patients, comparing twice-weekly MPD-PUVA with three times-weekly skin typing-PUVA, in order to test this hypothesis. Although clearance rates were comparable between the two regimens, there was no overall significant difference in the number of treatments or in the cumulative UVA doses at clearance. However, for patients with skin types I and II the cumulative UVA dose was significantly higher using the twice-weekly MPD regimen (70.OJ/cm{sup 2} vs. 55.8J/cm{sup 2}; P<0.05). Our results do not confirm that there is a reduction in cumulative UVA dosage with twice-weekly MPD-PUVA. (Author).

  10. Correlation between weekly working time and burnout syndrome among anesthesiologists of Maceió-AL.

    Science.gov (United States)

    Barbosa, Fabiano Timbó; Eloi, Raissa Jardelino; Santos, Luciano Menezes Dos; Leão, Bruna Acioly; Lima, Fernando José Camelo de; Sousa-Rodrigues, Célio Fernando de

    The current jobs are insufficient to determine the causative agent, as well as to identify characteristic high risk profiles for BS, leaving a clear need for more studies to this end. This study objective was to evaluate the correlation between weekly workload and BS dimensions. An observational, descriptive, cross-sectional study performed with 43 anesthesiologists from Maceió-AL, with the application of Maslach Burnout Inventory (MBI) forms. Pearson's correlation coefficient r was used for the three dimensions and a 95% confidence interval for the prevalence of burnout syndrome and high scores in all three dimensions. Among the studied physicians, 51.16% were male and the average age was 49.82±12.05 years. For physicians who have been diagnosed with BS through the MBI, the average weekly working time 69.27±22.39h. The high level of frequency in at least one of the three dimensions was found in 67.44% of physicians, with this percentage being considered diagnostic for burnout syndrome in this population. This study showed no correlation between the weekly working time and the BS dimensions in this population. Copyright © 2016 Sociedade Brasileira de Anestesiologia. Published by Elsevier Editora Ltda. All rights reserved.

  11. Skeletal Muscle Contraction Time and Tone Decrease After 8 Weeks of Plyometric Training.

    Science.gov (United States)

    Zubac, Damir; Šimunič, Boštjan

    2017-06-01

    The aim of the study was to examine whether an improvement in jumping performance after 8 weeks of plyometric training (PT) runs in parallel with changes in lower-limb skeletal muscle contractile properties. Using noninvasive tensiomyography (TMG), we assessed contraction time (Tc) and the maximal amplitude of radial displacement (Dm) in 20 subjects (50% men; age 22.4 ± 4.7 years of age), randomly divided in PT group (N = 10; PLYO) and a control group (N = 10; CTRL). The PLYO performed 8 weeks of PT. Tensiomyography was measured in 5 leg skeletal muscles: vastus lateralis (VL), biceps femoris (BF), tibialis anterior (TA), gastrocnemius medialis (GM), and gastrocnemius lateralis (GL). Additionally, we evaluated countermovement jump (CMJ) height improvement on a ground force plate. Assessments were repeated before and after PT. After 8 weeks of PT, CMJ height increased by 12.2% in PLYO (p = 0.015), but not in CRTL. Contraction time, which is related to myosin heavy-chain type 1 (MHC-1) proportion, decreased in VL (-8.7%; p muscle tone, decreased in BF (-26.5%; p = 0.032), GM (-14.9%; p = 0.017), GL (-31.5%; p = 0.017), but not in TA (-16.8%; p = 0.113) and VL (-6.0%; p = 0.654). After PT, jumping performance increased, which was paralleled by decreased Tc and decreased muscle tone. Additionally, adaptations to contractile properties were muscle specific, which is important for future studies. It seems that adjustments were dose dependent, being higher in muscles with lower habitual load.

  12. Investigation of Noises in GPS Time Series: Case Study on Epn Weekly Solutions

    Science.gov (United States)

    Klos, Anna; Bogusz, Janusz; Figurski, Mariusz; Kosek, Wieslaw; Gruszczynski, Maciej

    2014-05-01

    The noises in GPS time series are stated to be described the best by the combination of white (Gaussian) and power-law processes. They are mainly the effect of mismodelled satellite orbits, Earth orientation parameters, atmospheric effects, antennae phase centre effects, or of monument instability. Due to the fact, that velocities of permanent stations define the kinematic reference frame, they have to fulfil the requirement of being stable at 0.1 mm/yr. The previously performed researches showed, that the wrong assumption of noise model leads to the underestimation of velocities and their uncertainties from 2 up to even 11, especially in the Up direction. This presentation focuses on more than 200 EPN (EUREF Permanent Network) stations from the area of Europe with various monument types (concrete pillars, buildings, metal masts, with or without domes, placed on the ground or on the rock) and coordinates of weekly changes (GPS weeks 0834-1459). The topocentric components (North, East, Up) in ITRF2005 which come from the EPN Re-Processing made by the Military University of Technology Local Analysis Centre (MUT LAC) were processed with Maximum Likelihood Estimation (MLE) using CATS software. We have assumed the existence of few combinations of noise models (these are: white, flicker and random walk noise with integer spectral indices and power-law noise models with fractional spectral indices) and investigated which of them EPN weekly time series are likely to follow. The results show, that noises in GPS time series are described the best by the combination of white and flicker noise model. It is strictly related to the so-called common mode error (CME) that is spatially correlated error being one of the dominant error source in GPS solutions. We have assumed CME as spatially uniform, what was a good approximation for stations located hundreds of kilometres one to another. Its removal with spatial filtering reduces the amplitudes of white and flicker noise by a

  13. The Online GVP/USGS Weekly Volcanic Activity Report: Providing Timely Information About Worldwide Volcanism

    Science.gov (United States)

    Mayberry, G. C.; Guffanti, M. C.; Luhr, J. F.; Venzke, E. A.; Wunderman, R. L.

    2001-12-01

    The awesome power and intricate inner workings of volcanoes have made them a popular subject with scientists and the general public alike. About 1500 known volcanoes have been active on Earth during the Holocene, approximately 50 of which erupt per year. With so much activity occurring around the world, often in remote locations, it can be difficult to find up-to-date information about current volcanism from a reliable source. To satisfy the desire for timely volcano-related information the Smithsonian Institution and US Geological Survey combined their strengths to create the Weekly Volcanic Activity Report. The Smithsonian's Global Volcanism Program (GVP) has developed a network of correspondents while reporting worldwide volcanism for over 30 years in their monthly Bulletin of the Global Volcanism Network. The US Geological Survey's Volcano Hazards Program studies and monitors volcanoes in the United States and responds (upon invitation) to selected volcanic crises in other countries. The Weekly Volcanic Activity Report is one of the most popular sites on both organization's websites. The core of the Weekly Volcanic Activity Report is the brief summaries of current volcanic activity around the world. In addition to discussing various types of volcanism, the summaries also describe precursory activity (e.g. volcanic seismicity, deformation, and gas emissions), secondary activity (e.g. debris flows, mass wasting, and rockfalls), volcanic ash hazards to aviation, and preventative measures. The summaries are supplemented by links to definitions of technical terms found in the USGS photoglossary of volcano terms, links to information sources, and background information about reported volcanoes. The site also includes maps that highlight the location of reported volcanoes, an archive of weekly reports sorted by volcano and date, and links to commonly used acronyms. Since the Weekly Volcanic Activity Report's inception in November 2000, activity has been reported at

  14. US stock market efficiency over weekly, monthly, quarterly and yearly time scales

    Science.gov (United States)

    Rodriguez, E.; Aguilar-Cornejo, M.; Femat, R.; Alvarez-Ramirez, J.

    2014-11-01

    In financial markets, the weak form of the efficient market hypothesis implies that price returns are serially uncorrelated sequences. In other words, prices should follow a random walk behavior. Recent developments in evolutionary economic theory (Lo, 2004) have tailored the concept of adaptive market hypothesis (AMH) by proposing that market efficiency is not an all-or-none concept, but rather market efficiency is a characteristic that varies continuously over time and across markets. Within the AMH framework, this work considers the Dow Jones Index Average (DJIA) for studying the deviations from the random walk behavior over time. It is found that the market efficiency also varies over different time scales, from weeks to years. The well-known detrended fluctuation analysis was used for the characterization of the serial correlations of the return sequences. The results from the empirical showed that interday and intraday returns are more serially correlated than overnight returns. Also, some insights in the presence of business cycles (e.g., Juglar and Kuznets) are provided in terms of time variations of the scaling exponent.

  15. Perceived behavioral control as a potential precursor of walking three times a week: Patient's perspectives

    Science.gov (United States)

    Busse, Peter

    2018-01-01

    Background Behavior change theories can identify people’s main motivations to engage in recommended health practices and thus provide better tools to design interventions, particularly human centered design interventions. Objectives This study had two objectives: (a) to identify salient beliefs about walking three times a week for 30 minutes nonstop among patients with hypertension in a low-resource setting and, (b) to measure the relationships among intentions, attitudes, perceived social pressure and perceived behavioral control about this behavior. Methods Face-to-face interviews with 34 people living with hypertension were conducted in September-October 2011 in Lima, Peru, and data analysis was performed in 2015. The Reasoned Action Approach was used to study the people’s decisions to walk. We elicited people’s salient beliefs and measured the theoretical constructs associated with this behavior. Results Results pointed at salient key behavioral, normative and control beliefs. In particular, perceived behavioral control appeared as an important determinant of walking and a small set of control beliefs were identified as potential targets of health communication campaigns, including (not) having someone to walk with, having work or responsibilities, or having no time. Conclusions This theory-based study with a focus on end-users provides elements to inform the design of an intervention that would motivate people living with hypertension to walk on a regular basis in low-resource settings. PMID:29451917

  16. Survival with Three-Times Weekly In-Center Nocturnal Versus Conventional Hemodialysis

    Science.gov (United States)

    Xu, Jianglin; Suri, Rita S.; Nesrallah, Gihad; Lindsay, Robert; Garg, Amit X.; Lester, Keith; Ofsthun, Norma; Lazarus, Michael; Hakim, Raymond M.

    2012-01-01

    Whether the duration of hemodialysis treatments improves outcomes remains controversial. Here, we evaluated survival and clinical changes associated with converting from conventional hemodialysis (mean=3.75 h/treatment) to in-center nocturnal hemodialysis (mean=7.85 h/treatment). All 959 consecutive patients who initiated nocturnal hemodialysis for the first time in 77 Fresenius Medical Care facilities during 2006 and 2007 were eligible. We used Cox models to compare risk for mortality during 2 years of follow-up in a 1:3 propensity score–matched cohort of 746 nocturnal and 2062 control patients on conventional hemodialysis. Two-year mortality was 19% among nocturnal hemodialysis patients compared with 27% among conventional patients. Nocturnal hemodialysis associated with a 25% reduction in the risk for death after adjustment for age, body mass index, and dialysis vintage (hazard ratio=0.75, 95% confidence interval=0.61–0.91, P=0.004). With respect to clinical features, interdialytic weight gain, albumin, hemoglobin, dialysis dose, and calcium increased on nocturnal therapy, whereas postdialysis weight, predialysis systolic blood pressure, ultrafiltration rate, phosphorus, and white blood cell count declined (all P<0.001). In summary, notwithstanding the possibility of residual selection bias, conversion to treatment with nocturnal hemodialysis associates with favorable clinical features, laboratory biomarkers, and improved survival compared with propensity score–matched controls. The potential impact of extended treatment time on clinical outcomes while maintaining a three times per week hemodialysis schedule requires evaluation in future clinical trials. PMID:22362905

  17. The Seated Inactivity Trial (SIT): Physical Activity and Dietary Outcomes Associated With 8 Weeks of Imposed Sedentary Time.

    Science.gov (United States)

    Cull, Brooke J; Haub, Mark D; Rosenkranz, Richard R; Lawler, Thomas; Rosenkranz, Sara K

    2016-03-01

    Sedentary time is an independent risk factor for chronic diseases and mortality. It is unknown whether active adults alter their dietary and/or physical activity behaviors in response to imposed sedentary time, possibly modifying risk. The aim of this study was to determine whether imposed sedentary time would alter typical behaviors of active adults. Sixteen physically active, young adults were randomized to the no-intervention control (CON, n = 8) group or the sedentary-intervention (SIT, n = 8) group. SIT participants attended monitored sedentary sessions (8 wk, 10 h/wk). Assessments including diet and physical activity occurred at baseline, week 4, and week 9. There were no differences (P > .05) between CON and SIT groups for step counts or time spent in sedentary, light, moderate, or vigorous physical activity when comparing a week during imposed sedentary time (week 4) to baseline and week 9. At week 4, caloric intake was not different from baseline (P > .05) in either group. Caloric intake decreased significantly (P > .05) in SIT from baseline to week 9. Active adults did not alter physical activity or dietary behaviors during the imposed sedentary intervention. However, SIT reduced caloric intake from baseline to week 9, indicating a possible compensatory response to imposed sitting in active adults.

  18. It's Time to Start Changing the Game: A 12-Week Workplace Team Sport Intervention Study.

    Science.gov (United States)

    Brinkley, Andrew; McDermott, Hilary; Grenfell-Essam, Rachel; Munir, Fehmidah

    2017-08-23

    A 12-week multi-team sport programme was provided to employees of a large services organisation and conducted in workplaces. This programme was used to investigate the short-term effect of regular sports team participation on individual employee and organisational health. A large services organisation participated in this study. Two regional worksites of office workers were assigned as the team sport (intervention) (n = 28 participants) or control (n = 20 participants) groups. The team sport sessions were underpinned by psychological behaviour change theory and consisted of weekly 1-h team sport sessions for 12 weeks. Measures of aerobic fitness, physical activity behaviour, group cohesion, interaction and communication, psychological wellbeing, health, anthropometrics and workplace experiences were recorded pre- and post-intervention. Data were analysed using a series of mixed ANOVAs. After 12 weeks significant improvements were observed in VO 2 max (+ 4.5 ± 5.8 ml/min kg, P employees, and promote interpersonal communication between colleagues. Individual health outcomes and social interactions have the capacity to influence the health of the organisation. The extent of which these findings are replicable across a scope of organisations should be examined objectively over the long term.

  19. The four-day working week, unknown, unloved. Research into the organisational implications of working time reduction

    OpenAIRE

    Sels, Luc; Dejonckheere, Johan

    2000-01-01

    This contribution aims to bring clarity into the 'organisational implications' of one specific form of working time reduction, namely the four-day working week. We start by defining the concept of the four-day working week. In the second part, we look at ways Belgian authorities are trying to encourage the four-day working week, met by little enthusiasm from the business world. This reluctance stems from ignorance about the effects on performance and organisation. For this reason, we have con...

  20. Timing of umbilical cord clamping among infants born at 22 through 27 weeks' gestation.

    Science.gov (United States)

    Backes, C H; Huang, H; Iams, J D; Bauer, J A; Giannone, P J

    2016-01-01

    To investigate the safety, feasibility and efficacy of delayed cord clamping (DCC) compared with immediate cord clamping (ICC) at delivery among infants born at 22 to 27 weeks' gestation. This was a pilot, randomized, controlled trial in which women in labor with singleton pregnancies at 22 to 27 weeks' gestation were randomly assigned to ICC (cord clamped at 5 to 10 s) or DCC (30 to 45 s). Forty mother-infant pairs were randomized. Infants in the ICC and DCC groups had mean gestational ages (GA) of 24.6 and 24.4 weeks, respectively. No differences were observed between the groups across all available safety measures, although infants in the DCC group had higher admission temperatures than infants in the ICC group (97.4 vs. 96.2 °F, P=0.04). During the first 24 h of life, blood pressures were lower in the ICC group than in the DCC group (P<0.05), despite a threefold greater incidence of treatment for hypotension (45% vs. 12%, P<0.01). Infants in the ICC group had increased numbers of red blood transfusions (in first 28 days of life) than infants in DCC group (4.1±3.9 vs. 2.8±2.2, P=0.04). Among infants born at an average GA of 24 weeks', DCC appears safe, logistically feasible, and offers hematological and circulatory advantages compared with ICC. A more comprehensive appraisal of this practice is needed.

  1. It's Time to Start Changing the Game: A 12-Week Workplace Team Sport Intervention Study

    OpenAIRE

    Brinkley, Andrew; McDermott, Hilary; Grenfell-Essam, Rachel; Munir, Fehmidah

    2017-01-01

    Background A 12-week multi-team sport programme was provided to employees of a large services organisation and conducted in workplaces. This programme was used to investigate the short-term effect of regular sports team participation on individual employee and organisational health. Methods A large services organisation participated in this study. Two regional worksites of office workers were assigned as the team sport (intervention) (n?=?28 participants) or control (n?=?20 participants) grou...

  2. Eating disorders awareness week: the effectiveness of a one-time body image dissatisfaction prevention session.

    Science.gov (United States)

    Ridolfi, Danielle R; Vander Wal, Jillion S

    2008-01-01

    The purpose of this study was to assess the effectiveness of a body image dissatisfaction prevention session that provided information on body image and media literacy to college women. Participants were 81 undergraduates who were randomly assigned to attend either a body image intervention or a control intervention. Participants completed measures at pre- and post-intervention and at 4-week follow-up. The body image group improved significantly more than the control group on body shape concerns, but not on the other outcome variables. Efficacious interventions capable of reaching large numbers of women are necessary to help dispel the "normative discontent" prevalent today.

  3. The two-week pediatric surgery rotation: is it time wasted?

    Science.gov (United States)

    Dutta, S; Wales, P W; Fecteau, A

    2004-05-01

    With increasing medical school emphasis on generalist training and decreasing enrollment in surgical residency, the authors assessed the adequacy of a 2-week pediatric surgery rotation on meeting the learning and competency objectives outlined in The Canadian Association of Pediatric Surgeons' Self-Directed Evaluation Tool. A prospective survey was conducted of 39 clinical clerks. An anonymous self-assessment scale measuring competency objectives (medical and psychosocial) was administered pre-and postrotation. Also, exposure to pediatric surgical conditions from a list of "essential" and "nonessential" learning objectives was measured. Statistical analysis was performed using paired t test with significance at.05 level. Response rate was 77% and 54% for the competency and learning objectives, respectively. Students reported improvement in medical (P awareness of the breadth of pediatric surgical practice (P <.0001; 95% CI 2.06, 3.18). A 2-week rotation in pediatric surgery appears adequate in fulfilling most competency and learning objectives, but discussion is needed about how to best assess student competency, which topics are considered essential, and the long-term effect on recruitment to the profession.

  4. Walking four times weekly for at least 15 min is associated with longevity in a cohort of very elderly people.

    Science.gov (United States)

    Fortes, Cristina; Mastroeni, Simona; Sperati, Alessandra; Pacifici, Roberta; Zuccaro, PierGiorgio; Francesco, Forastiere; Agabiti, Nerina; Piras, Giovanna; Amleto, D'Amicis; Ebrahim, Shah

    2013-03-01

    This study investigated the role of walking outdoors on longevity, controlling for individual and other life-style factors as possible confounders. A 10-year cohort study was conducted with 152 self-caring and mobile, mean age 80 years, were enrolled in the study. Information on socio-demographic characteristics, clinical and biochemical data, diet, physical activity, smoking, depression status, cognitive status and anthropometrics measurements, were obtained for all participants. Cox proportional-hazards models were used to determine independent predictors of longevity. During the 10-years of follow-up, 96 (63%) died. Old age, chronic diseases, smoking, depression, CD4/CD8 ratio and coffee consumption were significantly predictors of mortality. Over-all survival was highest for subjects walking at open air for 4 times weekly for at least 15 min in comparison to subjects walking less than 4 times weekly (40% versus 22%). After adjusting for sex, age, education, chronic diseases, smoking, Body Mass Index and CD4/CD8 ratio, elderly people walking at open air for four times weekly had 40% decreased risk of mortality that individuals who walked less than four times weekly [relative risk (RR)=0.53; 95% confidence interval (CI)=0.32-0.88, p=0.01]. Findings suggest an independent and protective effect of walking on mortality and supports the encouragement of physical activity in advanced age for increasing longevity. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

  5. Adaptive Changes After 2 Weeks of 10-s Sprint Interval Training With Various Recovery Times

    Directory of Open Access Journals (Sweden)

    Robert A. Olek

    2018-04-01

    Full Text Available Purpose: The aim of this study was to compare the effect of applying two different rest recovery times in a 10-s sprint interval training session on aerobic and anaerobic capacities as well as skeletal muscle enzyme activities.Methods: Fourteen physically active but not highly trained male subjects (mean maximal oxygen uptake 50.5 ± 1.0 mlO2·kg−1·min−1 participated in the study. The training protocol involved a series of 10-s sprints separated by either 1-min (SIT10:1 or 4-min (SIT10:4 of recovery. The number of sprints progressed from four to six over six sessions separated by 1–2 days rest. Pre and post intervention anthropometric measurements, assessment of aerobic, anaerobic capacity and muscle biopsy were performed. In the muscle samples maximal activities of citrate synthase (CS, 3-hydroxyacylCoA dehydrogenase (HADH, carnitine palmitoyl-transferase (CPT, malate dehydrogenase (MDH, and its mitochondrial form (mMDH, as well as lactate dehydrogenase (LDH were determined. Analysis of variance was performed to determine changes between conditions.Results: Maximal oxygen uptake improved significantly in both training groups, by 13.6% in SIT10:1 and 11.9% in SIT10:4, with no difference between groups. Wingate anaerobic test results indicated main effect of time for total work, peak power output and mean power output, which increased significantly and similarly in both groups. Significant differences between training groups were observed for end power output, which increased by 10.8% in SIT10:1, but remained unchanged in SIT10:4. Both training protocols induced similar increase in CS activity (main effect of time p < 0.05, but no other enzymes.Conclusion: Sprint interval training protocols induce metabolic adaptation over a short period of time, and the reduced recovery between bouts may attenuate fatigue during maximal exercise.

  6. Family leisure-time physical activities – results of the “Juniors for Seniors” 15-week intervention programme

    Directory of Open Access Journals (Sweden)

    Pluta Beata

    2017-12-01

    Full Text Available Study aim: Both adequate time and quality time are important for the wellbeing of a family. The study evaluated the effective­ness of a 15-week family-based physical activity (PA intervention entitled “Junior for Seniors”. It included both children and parents. The paper focuses on an important topic - family-based leisure-time physical activity (LTPA. It is set in Polish primary schools, which is a novel approach. Regular physical activity for young people and their parents improves health and fitness including strength and endurance, promotes development of healthy bones and muscles, helps control weight and in­creases self-esteem.

  7. Effect of Eight Weekly Aerobic Training Program on Auditory Reaction Time and MaxVO[subscript 2] in Visual Impairments

    Science.gov (United States)

    Taskin, Cengiz

    2016-01-01

    The aim of study was to examine the effect of eight weekly aerobic exercises on auditory reaction time and MaxVO[subscript 2] in visual impairments. Forty visual impairment children that have blind 3 classification from the Turkey, experimental group; (age = 15.60 ± 1.10 years; height = 164.15 ± 4.88 cm; weight = 66.60 ± 4.77 kg) for twenty…

  8. An analysis of Emergency Medical Services demand: Time of day, day of the week, and location in the city.

    Science.gov (United States)

    Sariyer, Gorkem; Ataman, Mustafa Gokalp; Akay, Serhat; Sofuoglu, Turhan; Sofuoglu, Zeynep

    2017-06-01

    Effective planning of Emergency Medical Services (EMS), which is highly dependent on the analysis of past data trends, is important in reducing response time. Thus, we aimed to analyze demand for these services based on time and location trends to inform planning for an effective EMS. Data for this retrospective study were obtained from the Izmir EMS 112 system. All calls reaching these services during first six months of 2013 were descriptively analyzed, based on time and location trends as a heat-map form. The analyses showed that demand for EMS varied within different time periods of day, and according to day of the week. For the night period, demand was higher at the weekend compared to weekdays, whereas for daytime hours, demand was higher during the week. For weekdays, a statistically significant relation was observed between the call distribution of morning and evening periods. It was also observed that the percentage of demand changed according to location. Among 30 locations, the five most frequent destinations for ambulances, which are also correlated with high population densities, accounted for 55.66% of the total. The results of this study shed valuable light on the areas of call center planning and optimal ambulance locations of Izmir, which can also be served as an archetype for other cities.

  9. Short-term results of a 5-week comprehensive cardiac rehabilitation program after first-time myocardial infarction.

    Science.gov (United States)

    Fallavollita, Luca; Marsili, Bruno; Castelli, Sandro; Cucchi, Francesca; Santillo, Elpidio; Marini, Luciano; Balestrini, Fabrizio

    2016-03-01

    A prospective single-center interventional cohort study was conducted to evaluate the effects of a 5-week comprehensive cardiac rehabilitation program on terms exercise capacity, quality of life, echocardiographic findings and autonomic modulation after first-time myocardial infarction. We studied 37 consecutive post-myocardial infartion patients (mean age 66 years). All patients began a 5-week cardiac rehabilitation supervised training. The exercise program consisted of 40 minutes of training, three times a week, on a cycle ergometer at 60-80% of the maximal heart rate. At baseline and after training program we analyzed: the distance walked after the Six-Minutes Walking Test (6MWT); quality of life (QoL) assesed using the Psychological General Well-Being Inventory (PGWBI) questionnaire; echocardiographic finding and autonomic balance assesed heart rate variability (HRV). We observed statistically significant improvement in exercise capacity (from 423±94 to 496±13 m; P<0.05). Also we observed statistically significant improvements in the many PGWBI dimensions; particularly, anxiety +5.8% (from 18.11±5.2 to 19.12±4.4); depression +6.0% (from 12.00±3.0 to 12.73±2.4); positive well-being +6% (from 11.55±3.5 to 12.23±4.0); general health +10.3% (from 9.48±3.5 to 10.46±2.87); vitality +6.8% (from 12.96±4.2 to 13.85±4.2). Finally, we observed changes in HRV indices after training program: RR (from 903±169 ms to 952±163 ms; P<0.05), pNN50% (from 4.74±4.89 to 6.23±5.53; P<0.05), in time-domain; LF (from 274±169 to 362±233 ms2; P<0,05); HF (from 214±154 to 314±194 ms2; P<0.05) and LF/HF (from 1.53±0.54 to 1.24±0.47; P<0.05) in frequency-domain. The study suggest that a cardiac rehabilitation program in postmyocardial infarction improves exercise capacity, QoL and autonomic modulation.

  10. Do pregnant women prefer timing of elective cesarean section prior to versus after 39 weeks of gestation? Secondary analyses from a randomized controlled trial.

    Science.gov (United States)

    Glavind, J; Henriksen, T B; Kindberg, S F; Uldbjerg, N

    2014-11-01

    To evaluate women's preferences for timing of elective cesarean section (ECS) scheduled prior to versus after 39 completed weeks. Secondary analyses from a randomized controlled open-label trial were conducted at seven Danish tertiary hospitals from March 2009 to June 2011 with inclusion of singleton pregnant women with a healthy fetus. The women were allocated by a computerized telephone system to ECS scheduled at 38(+3) weeks or 39(+3) weeks of gestation. Dissatisfaction with timing of ECS and preferred timing of the procedure in a proposed future ECS delivery were evaluated. Data analyses were done by intention-to-treat, using logistic regression. A total of 1196 women (94%) completed an online questionnaire at follow-up eight weeks postpartum. In the 38 weeks group, 61 (10%) women 601 were dissatisfied with the timing of their ECS, whereas in the 39 weeks group 157 (26%) of 595 were dissatisfied (adjOR 3.18, 95% CI 2.30; 4.40). The proportion of women who preferred the same timing in a future ECS were 272 (45%) in the 38 weeks group compared to 232 (39%) in the 39(+3) weeks group (adjOR 0.75, 95% CI 0.60; 0.95). The women in this trial preferred ECS scheduled prior to 39 weeks of gestation.

  11. Trends in screen time on week and weekend days in a representative sample of Southern Brazil students.

    Science.gov (United States)

    Lopes, Adair S; Silva, Kelly S; Barbosa Filho, Valter C; Bezerra, Jorge; de Oliveira, Elusa S A; Nahas, Markus V

    2014-12-01

    Economic and technological improvements can help increase screen time use among adolescents, but evidence in developing countries is scarce. The aim of this study was to examine changes in TV watching and computer/video game use patterns on week and weekend days after a decade (2001 and 2011), among students in Santa Catarina, southern Brazil. A comparative analysis of two cross-sectional surveys that included 5 028 and 6 529 students in 2001 and 2011, respectively, aged 15-19 years. The screen time use indicators were self-reported. 95% Confidence intervals were used to compare the prevalence rates. All analyses were separated by gender. After a decade, there was a significant increase in computer/video game use. Inversely, a significant reduction in TV watching was observed, with a similar magnitude to the change in computer/video game use. The worst trends were identified on weekend days. The decrease in TV watching after a decade appears to be compensated by the increase in computer/video game use, both in boys and girls. Interventions are needed to reduce the negative impact of technological improvements in the lifestyles of young people, especially on weekend days. © The Author 2014. Published by Oxford University Press on behalf of Faculty of Public Health. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  12. Climate response to changes in atmospheric carbon dioxide and solar irradiance on the time scale of days to weeks

    International Nuclear Information System (INIS)

    Cao Long; Bala, Govindasamy; Caldeira, Ken

    2012-01-01

    Recent studies show that fast climate response on time scales of less than a month can have important implications for long-term climate change. In this study, we investigate climate response on the time scale of days to weeks to a step-function quadrupling of atmospheric CO 2 and contrast this with the response to a 4% increase in solar irradiance. Our simulations show that significant climate effects occur within days of a stepwise increase in both atmospheric CO 2 content and solar irradiance. Over ocean, increased atmospheric CO 2 warms the lower troposphere more than the surface, increasing atmospheric stability, moistening the boundary layer, and suppressing evaporation and precipitation. In contrast, over ocean, increased solar irradiance warms the lower troposphere to a much lesser extent, causing a much smaller change in evaporation and precipitation. Over land, both increased CO 2 and increased solar irradiance cause rapid surface warming that tends to increase both evaporation and precipitation. However, the physiological effect of increased atmospheric CO 2 on plant stomata reduces plant transpiration, drying the boundary layer and decreasing precipitation. This effect does not occur with increased solar irradiance. Therefore, differences in climatic effects from CO 2 versus solar forcing are manifested within days after the forcing is imposed. (letter)

  13. The timing of compositionally-zoned magma reservoirs and mafic 'priming' weeks before the 1912 Novarupta-Katmai rhyolite eruption

    Science.gov (United States)

    Singer, Brad S.; Costa, Fidel; Herrin, Jason S.; Hildreth, Wes; Fierstein, Judith

    2016-01-01

    The June 6, 1912 eruption of more than 13 km3 of dense rock equivalent (DRE) magma at Novarupta vent, Alaska was the largest of the 20th century. It ejected >7 km3 of rhyolite, ~1.3 km3 of andesite and ~4.6 km3 of dacite. Early ideas about the origin of pyroclastic flows and magmatic differentiation (e.g., compositional zonation of reservoirs) were shaped by this eruption. Despite being well studied, the timing of events that led to the chemically and mineralogically zoned magma reservoir remain poorly known. Here we provide new insights using the textures and chemical compositions of plagioclase and orthopyroxene crystals and by reevaluating previous U-Th isotope data. Compositional zoning of the magma reservoir likely developed a few thousand years before the eruption by several additions of mafic magma below an extant silicic reservoir. Melt compositions calculated from Sr contents in plagioclase fill the compositional gap between 68 and 76% SiO2 in whole pumice clasts, consistent with uninterrupted crystal growth from a continuum of liquids. Thus, our findings support a general model in which large volumes of crystal-poor rhyolite are related to intermediate magmas through gradual separation of melt from crystal-rich mush. The rhyolite is incubated by, but not mixed with, episodic recharge pulses of mafic magma that interact thermochemically with the mush and intermediate magmas. Hot, Mg-, Ca-, and Al-rich mafic magma intruded into, and mixed with, deeper parts of the reservoir (andesite and dacite) multiple times. Modeling the relaxation of the Fe-Mg concentrations in orthopyroxene and Mg in plagioclase rims indicates that the final recharge event occurred just weeks prior to the eruption. Rapid addition of mass, volatiles, and heat from the recharge magma, perhaps aided by partial melting of cumulate mush below the andesite and dacite, pressurized the reservoir and likely propelled a ~10 km lateral dike that allowed the overlying rhyolite to reach the surface.

  14. Chemical characterization of atmospheric dust from a weekly time series in the north Red Sea between 2006 and 2010

    Science.gov (United States)

    Torfstein, Adi; Teutsch, Nadya; Tirosh, Ofir; Shaked, Yeala; Rivlin, Tanya; Zipori, Assaf; Stein, Mordechai; Lazar, Boaz; Erel, Yigal

    2017-08-01

    Atmospheric dust loads and chemical compositions serve as a key link between global climate patterns and marine biogeochemical cycles. The primary source of atmospheric dust in the world today is the Sahara-Arabian desert belt. Although this source was also active during the Quaternary, the interpretation of paleo-dust records and their effects on marine ecosystems is complicated by the scarcely reported atmospheric load patterns of bioavailable phases (i.e., water and acid leachable phases) and present-day contamination of anthropogenic components. This study reports a multi-annual time series of atmospheric dust loads (2006-2016) and their chemical compositions (2006-2010) collected in the north Gulf of Aqaba (north Red Sea) at a weekly to bi-weekly resolution. Major and trace element abundances in each sample are reported for three fractions: water-soluble salts, carbonates and oxides (weak acid leach), and Al-silicates. Dust loads vary seasonally from low values in late summer (∼20-30 μg m-3) to higher values in the fall, and highest values in late winter and early spring (∼150-250 μg m-3). Major and trace element abundances allow to distinguish between the sources and chemical compositions that dominate high and low dust loads in each season. The water leachable fraction (L0) is relatively enriched in Na, Ca, K and Mg, the acid-leachable fraction (L1) is enriched in Ca as well as Na, Al, Mg, Zn, Cd and Pb, and the silicate residue (L2) in Al and Fe. High dust loads occurring mainly during winter and spring months are characterized by low Mg/Ca (L1, L2), low K/Al and Na/Al (L1) and high Ca/Al (L1), high Mg/Al (L2) and relatively un-weathered (L2) contents. High dust load intervals during winter months are characterized by low passing air masses originating from the Sahara, while the ambient winter dust (low dust load) is associated with proximal source regions from the East Sahara and Arabian Peninsula. During late winter and spring months, high dust

  15. The combined influence of leisure-time physical activity and weekly alcohol intake on fatal ischaemic heart disease and all-cause mortality

    DEFF Research Database (Denmark)

    Pedersen, Jane Østergaard; Heitmann, Berit Lilienthal; Schnohr, Peter

    2008-01-01

    AIMS: To determine the combined influence of leisure-time physical activity and weekly alcohol intake on the risk of subsequent fatal ischaemic heart disease (IHD) and all-cause mortality. METHODS AND RESULTS: Prospective cohort study of 11 914 Danes aged 20 years or older and without pre...... had the highest HR of both fatal IHD and all-cause mortality within each category of weekly alcohol intake. Thus, the HR of both fatal IHD and all-cause mortality were low among the physically active who had a moderate alcohol intake. Conclusion Leisure-time physical activity and a moderate weekly...... alcohol intake are both important to lower the risk of fatal IHD and all-cause mortality....

  16. The economic burden of time-loss injuries to youth players participating in week-long rugby union tournaments.

    Science.gov (United States)

    Brown, James C; Viljoen, Wayne; Lambert, Mike I; Readhead, Clint; Fuller, Chelsea; Van Mechelen, Willem; Verhagen, Evert

    2015-07-01

    Rugby Union ("rugby") is a popular sport with high injury risk. Burden of injury is described by the incidence and severity of injury. However reports have ignored the monetary cost of injuries. Therefore the aim of this study was to describe the monetary cost associated with youth rugby injuries. This descriptive study quantified medical treatments of injured players at the South African Rugby Union Youth tournaments in 2011/2012 and the days of work parents missed as a result of the injuries. A health insurer used these data to calculate associated costs. Legal guardians of the 421 injured players were contacted telephonically on a weekly basis until they returned to play. Treatments costs were estimated in South African Rands based on 2013 insurance rates and converted to US$ using purchasing power parities. Of the 3652 players, 2% (n=71) sought medical care after the tournament. For these players, average treatment costs were high (US$731 per player, 95% CI: US$425-US$1096), with fractures being the most expensive type of injury. Players with medical insurance had higher costs (US$937, 95% CI: US$486-US$1500) than those without (US$220, 95% CI: US$145-US$302). Although a minority of players sought follow-up treatment after the tournaments, the cost of these injuries was high. Players without medical insurance having lower costs may indicate that these players did not receive adequate treatment for their injuries. Injury prevention efforts should consider injuries with high costs and the treatment of players without medical insurance. Copyright © 2014 Sports Medicine Australia. Published by Elsevier Ltd. All rights reserved.

  17. Weekly working hours for Norwegian hospital doctors since 1994 with special attention to postgraduate training, work–home balance and the European Working Time Directive: a panel study

    Science.gov (United States)

    Rosta, Judith; Aasland, Olaf G

    2014-01-01

    Objectives To examine the weekly working hours of Norwegian hospital doctors from 1994 to 2012 with special emphasis on the quality of postgraduate training and work–home balance, and in relation to the requirements of the European Working Time Directive (EWTD). Design Panel study based on postal questionnaires. Setting Norway. Participants Unbalanced cohort of 1300–1600 doctors in 1994, 1995, 1996, 1997, 2000, 2002, 2004, 2006, 2008, 2010 and 2012. Outcome measures Self-reported total weekly working hours and whether 45 weekly working hours are too short, sufficient, or too long to meet the quality requirements of obligatory postgraduate training for junior doctors. Results From 1994 to 2012, the number of weekly working hours was stable for senior (46–47 h) and junior (45–46 h) hospital doctors. In 2012, significantly more senior (27–35%) than junior (11–20%) doctors reported suboptimal work–home balance, defined as working more than 48 h a week. The majority perceived the present situation with an average of 45 h per week for juniors as sufficient for obligatory postgraduate specialist training, but doctors of higher age (OR 1.04, 95% CI 1.01 to 1.08), senior doctors (1.07, 1.04 to 1.11) and doctors working in surgical specialties (OR 1 vs laboratory medicine 0.03, 0.01 to 0.25, internal medicine 0.31, 0.17 to 0.58, psychiatry 0.12, 0.04 to 0.36, paediatrics 0.36, 0.12 to 1.07, anaesthesiology 0.08, 0.02 to 0.39, gynaecology 0.07, 0.01 to 0.56 and others 0.39, 0.04 to 3.56) were more likely to want the work-week to be longer. Conclusions The weekly working hours of Norwegian hospital doctors were always below the EWTD requirements. A significant growth of hospital doctor density over the past two decades, national regulations and cultural values might be important factors. Specialty differences in perception of sufficient training time may call for more flexibility in working time regulations. PMID:25311038

  18. Weekly working hours for Norwegian hospital doctors since 1994 with special attention to postgraduate training, work-home balance and the European working time directive: a panel study.

    Science.gov (United States)

    Rosta, Judith; Aasland, Olaf G

    2014-10-13

    To examine the weekly working hours of Norwegian hospital doctors from 1994 to 2012 with special emphasis on the quality of postgraduate training and work-home balance, and in relation to the requirements of the European Working Time Directive (EWTD). Panel study based on postal questionnaires. Norway. Unbalanced cohort of 1300-1600 doctors in 1994, 1995, 1996, 1997, 2000, 2002, 2004, 2006, 2008, 2010 and 2012. Self-reported total weekly working hours and whether 45 weekly working hours are too short, sufficient, or too long to meet the quality requirements of obligatory postgraduate training for junior doctors. From 1994 to 2012, the number of weekly working hours was stable for senior (46-47 h) and junior (45-46 h) hospital doctors. In 2012, significantly more senior (27-35%) than junior (11-20%) doctors reported suboptimal work-home balance, defined as working more than 48 h a week. The majority perceived the present situation with an average of 45 h per week for juniors as sufficient for obligatory postgraduate specialist training, but doctors of higher age (OR 1.04, 95% CI 1.01 to 1.08), senior doctors (1.07, 1.04 to 1.11) and doctors working in surgical specialties (OR 1 vs laboratory medicine 0.03, 0.01 to 0.25, internal medicine 0.31, 0.17 to 0.58, psychiatry 0.12, 0.04 to 0.36, paediatrics 0.36, 0.12 to 1.07, anaesthesiology 0.08, 0.02 to 0.39, gynaecology 0.07, 0.01 to 0.56 and others 0.39, 0.04 to 3.56) were more likely to want the work-week to be longer. The weekly working hours of Norwegian hospital doctors were always below the EWTD requirements. A significant growth of hospital doctor density over the past two decades, national regulations and cultural values might be important factors. Specialty differences in perception of sufficient training time may call for more flexibility in working time regulations. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  19. WEEKLY WATCH

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    OPINION Taking Workers for a Ride While most people got to have time off with friends and family during the weeklong National Day holiday,some had to work.In accordance with China’s Labor Law,companies or organizations that keep employees working during legal holidays must pay the

  20. Use of mesalazine slow release suppositories 1 g three times per week to maintain remission of ulcerative proctitis: a randomised double blind placebo controlled multicentre study

    Science.gov (United States)

    Marteau, P; Crand, J; Foucault, M; Rambaud, J

    1998-01-01

    Background—Daily administration of rectal formulations of mesalazine is effective in preventing relapse of ulcerative proctitis. Maintenance of remission with lower doses would be an advantage. 
Aim—The efficacy of mesalazine suppositories (Pentasa) 1 g three times a week v placebo to maintain remission in patients with cryptogenetic proctitis was studied. 
Methods—Ninety five patients with cryptogenetic proctitis were randomised within two weeks of remission to receive for one year or until relapse three suppositories per week of either Pentasa (n=48) or placebo (n=47). In the case of a relapse, the patients received one suppository/day. 
Results—It was found that 25 of 48 subjects v 18 of 47 remained in remission in the mesalazine and placebo groups respectively. The relapse rate was lower in the mesalazine group for the following time intervals: 0-90 days (19% v 38%, p=0.035), 0-180 days (29% v 54%, p=0.017), 0-270 days (38% v 60%, p=0.031), and 0-365 days (48% v 62%, p=0.18). Treatment of relapse with one suppository/day induced remission in 11 of 18 and 2 of 26 patients in the mesalazine and placebo groups respectively (p=0.001). Overall, 61% v 28% patients remained in the protocol and were in remission at one year (p=0.001). Tolerance was good. 
Conclusion—Mesalazine suppositories 1 g three times a week are effective for preventing relapses of cryptogenetic proctitis. Increasing the dose to 1 g/day is effective in a high proportion of subjects who relapsed. 

 Keywords: inflammatory bowel disease; mesalazine; 5-aminosalicylic acid; topical treatments; proctitis PMID:9536943

  1. Twelve weeks of dance exergaming in overweight and obese adolescent girls: Transfer effects on physical activity, screen time, and self-efficacy.

    Science.gov (United States)

    Staiano, Amanda E; Beyl, Robbie A; Hsia, Daniel S; Katzmarzyk, Peter T; Newton, Robert L

    2017-03-01

    Given the low levels of physical activity (PA) among adolescent girls in the US, there is a need to identify tools to motivate increased PA. Although there is limited evidence that adolescents transfer PA from one context to another context, exergames (i.e., video games that require gross motor activity) may act as a gateway to promote overall PA outside of game play. The purpose of this study was to examine potential transfer effects (i.e., influences on external behaviors and psychological constructs) of a 12-week exergaming intervention on adolescent girls' PA, screen-time, and self-efficacy towards PA, as well as the intrinsic motivation of exergaming. Participants were 37 girls aged 14-18 years (65% African American, 35% White) who were overweight or obese (body mass index ≥ 85th percentile) and were recruited from the community via school, physicians, news media, and social media sites. Adolescents were randomly assigned to a 12-week group exergaming intervention (thirty-six 60 min sessions of group-based dance exergaming in a research laboratory using Kinect for Xbox 360) or to a no-treatment control group. Outcome variables included objectively measured PA (total) and self-reported leisure-time PA (discretionary time only) 1-week before vs . 1-week after the intervention; selected type and intensity of PA when placed in a gym setting for 30 min ("cardio free choice"); screen-time; self-efficacy towards PA; and intrinsic motivation towards exergaming. Attendance to the exergaming sessions was high (80%). Compared to the control group, the intervention group self-reported an increase in PA ( p = 0.035) and fewer hours watching TV/videos ( p = 0.01) after the intervention, but there were no significant differences in sedentary, light, moderate, or vigorous PA measured by accelerometry. The intervention group significantly improved self-efficacy towards PA ( p = 0.028). The intervention group highly rated intrinsic motivation towards exergaming. Twelve weeks

  2. Twelve weeks of dance exergaming in overweight and obese adolescent girls: Transfer effects on physical activity, screen time, and self-efficacy

    Science.gov (United States)

    Staiano, Amanda E.; Beyl, Robbie A.; Hsia, Daniel S.; Katzmarzyk, Peter T.; Newton, Robert L.

    2016-01-01

    Background Given the low levels of physical activity (PA) among adolescent girls in the US, there is a need to identify tools to motivate increased PA. Although there is limited evidence that adolescents transfer PA from one context to another context, exergames (i.e., video games that require gross motor activity) may act as a gateway to promote overall PA outside of game play. The purpose of this study was to examine potential transfer effects (i.e., influences on external behaviors and psychological constructs) of a 12-week exergaming intervention on adolescent girls’ PA, screen-time, and self-efficacy towards PA, as well as the intrinsic motivation of exergaming. Methods Participants were 37 girls aged 14–18 years (65% African American, 35% White) who were overweight or obese (body mass index ≥ 85th percentile) and were recruited from the community via school, physicians, news media, and social media sites. Adolescents were randomly assigned to a 12-week group exergaming intervention (thirty-six 60 min sessions of group-based dance exergaming in a research laboratory using Kinect for Xbox 360) or to a no-treatment control group. Outcome variables included objectively measured PA (total) and self-reported leisure-time PA (discretionary time only) 1-week before vs. 1-week after the intervention; selected type and intensity of PA when placed in a gym setting for 30 min (“cardio free choice”); screen-time; self-efficacy towards PA; and intrinsic motivation towards exergaming. Results Attendance to the exergaming sessions was high (80%). Compared to the control group, the intervention group self-reported an increase in PA (p = 0.035) and fewer hours watching TV/videos (p = 0.01) after the intervention, but there were no significant differences in sedentary, light, moderate, or vigorous PA measured by accelerometry. The intervention group significantly improved self-efficacy towards PA (p = 0.028). The intervention group highly rated intrinsic motivation

  3. Hygienic safety of reusable tap water filters (Germlyser® with an operating time of 4 or 8 weeks in a haematological oncology transplantation unit

    Directory of Open Access Journals (Sweden)

    Rochow Markus

    2007-05-01

    Full Text Available Abstract Background Microbial safe tap water is crucial for the safety of immunosuppressed patients. Methods To evaluate the suitability of new, reusable point-of-use filters (Germlyser®, Aquafree GmbH, Hamburg, Germany, three variations of a reusable filter with the same filter principle but with different outlets (with and without silver and inner surface coating of the filter encasements (with and without nano-crystalline silver were tested. The filter efficacy was monitored over 1, 4 and 8 weeks operating time in a haematological oncology transplantation unit equipped with 18 water outlets (12 taps, 6 showers. Results The filtered water fulfilled the requirements of absence of pathogens over time. From 348 samples, 8 samples (2.3% exceeded 100 cfu/ml (no sample ≥ 500 cfu/ml. As no reprocessed filter exhibited 100% filter efficacy in the final quality control after each reprocessing, these contaminations could be explained by retrograde contamination during use. Conclusion As a consequence of the study, the manufacturer recommends changing filters after 4 weeks in high risk areas and after 8 weeks in moderate infectious risk areas, together with routine weekly alcohol-based surface disinfection and additionally in case of visible contamination. The filter efficacy of the 3 filters types did not differ significantly regarding total bacterial counts. Manual reprocessing proved to be insufficient. Using a validated reprocessing in a washer/disinfector with alkaline, acid treatment and thermic disinfection, the filters were effectively reprocessable and now provide tap water meeting the German drinking water regulations as well as the WHO guidelines, including absence of pathogens.

  4. Imaging of the rabbit supraspinatus enthesis at 7 Tesla: a 4-week time course after repair surgery and effect of channeling.

    Science.gov (United States)

    Trudel, Guy; Melkus, Gerd; Cron, Greg O; Louati, Hakim; Sheikh, Adnan; Larson, Peder E Z; Schweitzer, Mark; Lapner, Peter; Uhthoff, Hans K; Laneuville, Odette

    2017-08-01

    To image the supraspinatus enthesis reformation of rabbit shoulders by magnetic resonance at 7 Tesla (T) using T2 mapping after surgical repair and to assess the effects of channeling aimed at enhancing enthesis reformation. In 112 rabbits, the distal supraspinatus (SSP) tendon was unilaterally detached and reattached after 1 week. At the first surgery, channeling was performed at the footprint in 64 rabbits. At the second surgery, the SSP tendon of all rabbits was re-attached to the greater tuberosity. The shoulders were harvested at 0, 1, 2, or 4 weeks after the repair surgery and were imaged at 7T. Quantitative T2 mapping was performed using multi slice two-dimensional multi-echo spin-echo sequence with fat saturation. Enthesis regions of interests were drawn on three slices at the footprint to measure T2 relaxation times. Tendon repair (F (2, 218)  = 44; P < 2.2e-16) and postoperative duration (F (3, 218)  = 4.8; P = 0.006) both affected significantly the T2 values while channeling had no significant effect. For the time effect, the only pair with a statistical difference was the 0-week and 4-week for the channeling groups (P = 0.023). Enthesis reformation early after surgical repair of the SSP distal tendon was characterized by increasing T2 values. 2 Technical Efficacy: Stage 1 J. MAGN. RESON. IMAGING 2017;46:461-467. © 2017 International Society for Magnetic Resonance in Medicine.

  5. Day of the week lost time occupational injury trends in the US by gender and industry and their implications for work scheduling.

    Science.gov (United States)

    Brogmus, G E

    2007-03-01

    While there is a growing body of research on the impact of work schedules on the risk of occupational injuries, there has been little investigation into the impact that the day of the week might have. The present research was completed to explore day of the week trends, reasons for such trends and the corresponding implications for work scheduling. Data for the number of injuries and illnesses involving days away from work (lost time; LT) in 2004 were provided by the US Bureau of Labor Statistics Office of Safety and Health Statistics. Data from the American Time Use Survey database were used to estimate work hours in 2004. From these two data sources, the rate of LT injuries and illnesses (per 200 000 work hours) by day of the week, industry sector and gender were estimated. The analysis revealed clear differences by day of the week, gender and major industry sector. Sundays had the highest rate overall--nearly 37% higher than the average of the remaining days, Monday to Saturday. Mondays had the next highest rate followed closely by Saturdays. This pattern was not the same for males and females. For males, Mondays had the highest LT rate (27% higher than the average of all other days) with all remaining days having essentially the same rate. For females, Sundays and Saturdays had much higher LT rates--122% and 60% higher, respectively, than the average weekday rate. There were also differences by industry and differences between genders by industry. The present analysis suggests that several factors may be contributing to the weekend and Monday trends observed. Lower-tenured (and younger) workers on the weekends, lower female management/supervision and second jobs on the weekend seem to be contributors to the high Saturday and Sunday LT rates. Differences in day of the week employment by industry did not account for the trends observed. Fraud and overtime also could not be confirmed as contributing to these trends. Monday trends were more complex to explain, with

  6. SU-E-J-229: Quantitative Assessment for Timely Adaptive Re-Planning Using Weekly Dose Monitoring for Head and Neck Cancer

    Energy Technology Data Exchange (ETDEWEB)

    Shang, Q; Liu, H; Greskovich, J; Koyfman, S; Xia, P [Cleveland Clinic, Cleveland, OH (United States); Li, Z [Cleveland Clinic, Cleveland, OH (United States); the 6th people' s hospital of Shanghai Jiaotong University, Shanghai, Shanghai (China)

    2014-06-01

    Purpose: For patients with head and neck (HN) cancer, mid-course adaptive radiation therapy (ART) is a common practice in our institution to accommodate anatomic changes. The aim of the study is to evaluate whether dose re-calculation on weekly verification images can provide quantitative assessment for timely adaptive re-planning with daily image-guided intensity modulated radiotherapy (IMRT). Methods: We retrospectively selected sixty daily verification images acquired on CT-on-rail/CBCT from ten HN patients. These image sets were typically a week apart. Among these patients, six patients received a mid-course ART. Contours of the tumors and organ-at-risks (OARs) were manually delineated by a physician on each verification CT. After placing the treatment iso-center on the verification CTs according to the recorded clinical shifts, daily dose was re-calculated with the same beam configuration as the original plan. For the purpose of this study, electron densities for both verification CTs and planning CTs were set to 1.0 g/cm3. Results: Two patients had D99 of the CTV < 97% of the planned dose for more than three fractions due to remarkable tumor volume shrinkages. D-max of the spinal cord exceeded a tolerance of 45 Gy for four fractions in additional two patients. D-mean of the parotid increased within 25% of the planned value. D-max of the brainstem and D-mean of the oral cavity did not show significant variation. If the re-planning criteria included D99 of the CTV < 97% of the planned dose and D-max of the spinal cord > 45 Gy, two out ten patients required ART at week 2 and two patients required ART at week 3, respectively. Conclusion: Weekly dose monitoring with re-calculation on verification images can provide quantitative dose guidance for timely adaptive re-planning. Future work will include accumulative dose analysis for the decision of adaptive re-planning. The study is supported in part by Siemens Medical Solutions.

  7. Do associations between objectively-assessed physical activity and neighbourhood environment attributes vary by time of the day and day of the week?

    DEFF Research Database (Denmark)

    Cerin, Ester; Mitáš, Josef; Cain, Kelli L

    2017-01-01

    , intersection density and land use mix were stronger in the mornings of weekdays and the afternoon/evening periods of both weekdays and weekend days. Associations between number of parks and MVPA were stronger in the mornings and afternoon/evenings irrespective of day of the week. Public transport density...... showed consistent positive associations with MVPA during weekends, while stronger effects on weekdays were observed in the morning and early evenings. CONCLUSIONS: This study suggests that space and time constraints in adults' daily activities are important factors that determine the impact...

  8. Circuit class therapy and 7-day-week therapy increase physiotherapy time, but not patient activity: early results from the CIRCIT trial.

    Science.gov (United States)

    English, Coralie; Bernhardt, Julie; Hillier, Susan

    2014-10-01

    The optimum model of physiotherapy service delivery for maximizing active task practice during rehabilitation after stroke is unknown. The purpose of the study was to examine the relative effectiveness of 2 alternative models of physiotherapy service delivery against a usual care control with regard to increasing patient activity. Substudy within a large 3-armed randomized controlled trial, which compared 3 different models of physiotherapy service delivery, was provided for 4 weeks during subacute, inpatient rehabilitation (n=283). The duration of all physiotherapy sessions was recorded. In addition, 32 participants were observed at 10-minute intervals for 1 weekday and 1 weekend day between 8:00 am and 4:30 pm. At each observation, we recorded physical activity, location, and people present. Participants receiving 7-day-week and circuit class therapy received an additional 3 hours and 22 hours of physiotherapy time, respectively, when compared with usual care. Participants were standing or walking for a median of 8.2% of observations. On weekdays, circuit class therapy participants spent more time in therapy-related activity (10.2% of observations) when compared with usual care participants (6.1% of observations). On weekends, 7-day therapy participants spent more time in therapy-related activity (4.2% of observations) when compared with both usual care and circuit class therapy participants (0% of observations for both groups). Activity levels outside of therapy sessions did not differ between groups. A greater dosage of physiotherapy time did not translate into meaningful increases in physical activity across the day. http://www.anzctr.org.au/. Unique identifier: ACTRN12610000096055. © 2014 American Heart Association, Inc.

  9. Twelve Weeks of Sprint Interval Training Improves Indices of Cardiometabolic Health Similar to Traditional Endurance Training despite a Five-Fold Lower Exercise Volume and Time Commitment.

    Directory of Open Access Journals (Sweden)

    Jenna B Gillen

    Full Text Available We investigated whether sprint interval training (SIT was a time-efficient exercise strategy to improve insulin sensitivity and other indices of cardiometabolic health to the same extent as traditional moderate-intensity continuous training (MICT. SIT involved 1 minute of intense exercise within a 10-minute time commitment, whereas MICT involved 50 minutes of continuous exercise per session.Sedentary men (27±8y; BMI = 26±6kg/m2 performed three weekly sessions of SIT (n = 9 or MICT (n = 10 for 12 weeks or served as non-training controls (n = 6. SIT involved 3x20-second 'all-out' cycle sprints (~500W interspersed with 2 minutes of cycling at 50W, whereas MICT involved 45 minutes of continuous cycling at ~70% maximal heart rate (~110W. Both protocols involved a 2-minute warm-up and 3-minute cool-down at 50W.Peak oxygen uptake increased after training by 19% in both groups (SIT: 32±7 to 38±8; MICT: 34±6 to 40±8ml/kg/min; p<0.001 for both. Insulin sensitivity index (CSI, determined by intravenous glucose tolerance tests performed before and 72 hours after training, increased similarly after SIT (4.9±2.5 to 7.5±4.7, p = 0.002 and MICT (5.0±3.3 to 6.7±5.0 x 10-4 min-1 [μU/mL]-1, p = 0.013 (p<0.05. Skeletal muscle mitochondrial content also increased similarly after SIT and MICT, as primarily reflected by the maximal activity of citrate synthase (CS; P<0.001. The corresponding changes in the control group were small for VO2peak (p = 0.99, CSI (p = 0.63 and CS (p = 0.97.Twelve weeks of brief intense interval exercise improved indices of cardiometabolic health to the same extent as traditional endurance training in sedentary men, despite a five-fold lower exercise volume and time commitment.

  10. “Do the Germans Really Work Six Weeks More than the French?” – Measuring Working Time with the Labour Force Survey in France and Germany

    Directory of Open Access Journals (Sweden)

    Körner Thomas

    2016-06-01

    Full Text Available Measuring working time is not only an important objective of the EU Labour Force Survey (LFS, but also a highly demanding task in terms of methodology. Against the background of a recent debate on the comparability of working time estimates in France and Germany, this article presents a comparative assessment of the measurement of working time in the Labour Force Survey obtained in both countries. It focuses on the measurement of the hours actually worked, the key working-time concept for short-term economic analysis and the National Accounts. The contribution systematically analyses the differences in the measurement approaches used in France and Germany in order to identify the methodological effects that hinder comparability. It comes to the conclusion that the LFS overstates the difference in hours actually worked in France and Germany and identifies question comprehension, rounding, editing effects, as well as certain aspects of the sampling design, as crucial factors of a reliable measurement in particular of absences from work during the reference week. We recommend continuing the work started in the European Statistical System towards the development of a model questionnaire in order to improve cross-national harmonisation of key variables such as hours actually worked.

  11. [Secondhand smoke exposure at home and leisure time according to the day of the week (working and non-working day) in Barcelona].

    Science.gov (United States)

    Martínez-Sánchez, José M; Fu, Marcela; Schiaffino, Anna; Sureda, Xisca; Saltó, Esteve; Moncada, Albert; Ariza, Carles; Nebot, Manel; Pascual, José A; Fernández, Esteve

    2012-01-01

    The objective of this study is to describe the differences in the exposure to secondhand smoke (SHS) at home and at leisure time according to the day of the week (working and non-working day) which exposure occurs in Barcelona. We carried out a cross-sectional study of a representative sample of adult (>16 years) non-smokers in Barcelona before the Spanish smoking law came into effect (years 2004-2005). We studied the prevalence of exposure to SHS at home and leisure time by means of a questionnaire and a biomarker (salivary cotinine). The questionnaire included questions on exposure to SHS on working days and nonworking days. The prevalence of exposure to SHS at home was 27.4% (6.8% exposed only on working days, 5.7% exposed only on non-working days, and 14.9% exposed on both working and non-working days). The prevalence of exposure to SHS at leisure time was 61.3% (10.7% exposed only on working days, 13.6% exposed only on non-working days, and 37.0% exposed on both working and non-working days). The exposure to SHS only on non-working days at leisure time decreases with age (χ(2) of trend = 183.7; phome on working and non-working days showed higher levels of salivary cotinine concentration, regardless of sex, age group, and educational level. In conclusion, the exposure to SHS occurs mainly during leisure time. Questions on SHS exposure according to working and non-working days allow to characterizing the exposure to SHS, especially when the exposure occurs at leisure time.

  12. Time Course of Improvement of Metabolic Parameters after a 12 Week Physical Exercise Programme in Patients with Type 2 Diabetes: The Influence of Gender in a Nigerian Population

    Directory of Open Access Journals (Sweden)

    A. F. Adeniyi

    2013-01-01

    Full Text Available Gender is a major determinant of the outcomes of many health interventions. This study documents the order of significant improvements in metabolic parameters of patients with type 2 diabetes mellitus (T2DM having metabolic syndrome within 12 weeks of physical exercise programmes. Twenty-nine patients, mean age 49.6 ± 3.7 years, presenting with high fasting plasma glucose, high triglycerides, hypertension, and high waist circumference undertook a thrice weekly aerobic and endurance exercise programme in addition to their drugs and diet. Variables were assessed at baseline and end of every two weeks for twelve weeks. Compared with baseline, significant improvement (P<0.05 in the metabolic parameters occurred in this order for the male participants: fasting glucose (2nd week, triglycerides and waist circumference (4th week, and systolic blood pressure (12th week. For the female participants, it was fasting glucose (4th week, triglycerides (6th week, and waist circumference (10th week. Regardless of the gender, fasting glucose was the first to improve significantly, followed by triglycerides. Hypertension did not improve significantly at all in the female participants as they may require more than twelve weeks of therapeutic exercise for any significant improvement in hypertension.

  13. Do time of birth, unit volume, and staff seniority affect neonatal outcome in deliveries at ≥34+0 weeks of gestation?

    Science.gov (United States)

    Reif, P; Pichler, G; Griesbacher, A; Lehner, G; Schöll, W; Lang, U; Hofmann, H; Ulrich, D

    2018-06-01

    We investigated whether time of birth, unit volume, and staff seniority affect neonatal outcome in neonates born at ≥34 +0 weeks of gestation. Population-based prospective cohort study. Ten public hospitals in the Austrian province of Styria. A total of 87 065 neonates delivered in the period 2004-2015. Based on short-term outcome data, generalised linear mixed models were used to calculate the risk for adverse and severely adverse neonatal outcomes according to time of birth, unit volume, and staff seniority. Neonatal composite adverse and severely adverse outcome measures. The odds ratio for severely adverse events during the night-time (22:01-07:29 hours) compared with the daytime (07:30-15:00 hours) was 1.35 (95% confidence interval, 95% CI 1.13-1.61). There were no significant differences in neonatal outcome comparing weekdays and weekends, and comparing office hours and shifts. Units with 500-1000 deliveries per year had the lowest risk for adverse events. Adverse and severely adverse neonatal outcomes were least common for midwife-guided deliveries, and became more frequent with the level of experience of the doctors attending the delivery. With increasing pregnancy risks, senior staff attending delivery and delivering in a tertiary centre reduce the odds ratio for adverse events. Different times of delivery were associated with increased adverse neonatal outcomes. The management of uncomplicated deliveries by less experienced staff showed no negative impact on perinatal outcome. In contrast, riskier pregnancies delivered by senior staff in a tertiary centre favour a better outcome. Achieving a better balance in the total number of labour ward staff during the day and the night appears to be a greater priority than increasing the continuous presence of senior obstetrical staff on the labour ward during the out-of-hours period. Deliveries during night time lead to a greater number of neonates experiencing severely adverse events. © 2017 Royal College of

  14. Variation in the human lymphocyte sister chromatid exchange frequency as a function of time: results of daily and twice-weekly sampling

    Energy Technology Data Exchange (ETDEWEB)

    Tucker, J.D.; Christensen, M.L.; Strout, C.L.; McGee, K.A.; Carrano, A.V.

    1987-01-01

    The variation in lymphocyte sister chromatid exchange (SCE) frequency was investigated in healthy nonsmokers who were not taking any medication. Two separate studies were undertaken. In the first, blood was drawn from four women twice a week for 8 weeks. These donors recorded the onset and termination of menstruation and times of illness. In the second study, blood was obtained from two women and two men for 5 consecutive days on two separate occasions initiated 14 days apart. Analysis of the mean SCE frequencies in each study indicated that significant temporal variation occurred in each donor, and that more variation occurred in the longer study. Some of the variation was found to be associated with the menstrual cycle. In the daily study, most of the variation appeared to be random, but occasional day-to-day changes occurred that were greater than those expected by chance. To determine how well a single SCE sample estimated the pooled mean for each donor in each study, the authors calculated the number of samples that encompassed that donor's pooled mean within 1 or more standard errors. For both studies, about 75% of the samples encompassed the pooled mean within 2 standard errors. An analysis of high-frequency cells (HFCs) was also undertaken. The results for each study indicate that the proportion of HFCs, compared with the use of Fisher's Exact test, is significantly more constant than the means, which were compared by using the t-test. These results coupled with our previous work suggest that HFC analysis may be the method of choice when analyzing data from human population studies.

  15. Chromosomal studies on 2 mL of celomic fluid obtained during the fifth week of development in the timed-pregnant baboon model.

    Science.gov (United States)

    Santolaya-Forgas, Joaquin; De Leon-Luis, Juan; Shen, Zhion; McCorquodale, Maureen

    2005-09-01

    To determine if chromosomal studies could be performed using 2 mL of celomicfluid obtained during the fifth postfertilization week in pregnant baboons. Nine ultrasound-guided celocenteses were performed. The initial 0.5 mL of celomic fluid was discarded to decrease maternal cell contamination. Approximately 2 mL of celomic fluid was then collected. The fluid was centrifuged and the supernatant removed to a final volume of 0.5 mL. The celomic fluid sample was placed in either a small plastic flaskette chamber slide with a mix of 0.5 mL celomic fluid, 1 mL of Amniomax, and 1 mL of usedfibroblast culture medium to spread on the entire surface (n=4), or a 3.5 x 1-cm plastic Petri dish with a 24 x 30-mm glass coverslip to keep the 0.5 mL celomic fluid mixed with 1 mL of Amniomax (Invitrogen, Carlsbad, California) within a 1 cm2 area (n=5). The medium was changed on day 5 and thereafter every second to third day. The cells were harvested when the number of cells appeared sufficient for chromosomal analysis. Standard chromosomal studies were possible in 5 of the 9 celomicfluid samples. Mean (+/-SD) celomic fluid volume used for culture was 1.85 +/- 0.3 mL. Mean (+/-SD) time to karyotype result was 18.8 +/- 1.8 days. The findings of this study suggest that there are living cells at 36-42 days of embryonic development in the extraembryonic celomic fluid of primates and that they can be cultured for chromosomal studies. However, significant improvements in understanding the biology of cells present at 5 weeks after fertilization in celomic fluid are needed to improve culture conditions.

  16. Long-term clinical parameters after switching to nocturnal haemodialysis : a Dutch propensity-score-matched cohort study comparing patients on nocturnal haemodialysis with patients on three-times-a-week haemodialysis/haemodiafiltration

    NARCIS (Netherlands)

    Jansz, Thijs Thomas; Özyilmaz, Akin; Grooteman, Muriel P C; Hoekstra, Tiny; Romijn, Marieke; Blankestijn, Peter J; Bots, Michael L; van Jaarsveld, Brigit C

    2018-01-01

    OBJECTIVES: Nocturnal haemodialysis (NHD), characterised by 8-hour sessions ≥3 times a week, is known to improve clinical parameters in the short term compared with conventional-schedule haemodialysis (HD), generally 3×3.5-4 hours a week. We studied long-term effects of NHD and used patients on

  17. Twelve weeks of dance exergaming in overweight and obese adolescent girls: Transfer effects on physical activity, screen time, and self-efficacy

    Directory of Open Access Journals (Sweden)

    Amanda E. Staiano

    2017-03-01

    Conclusion: Exergaming for 12 weeks was associated with positive impacts on adolescent girls' self-reported PA, television viewing, self-efficacy, and intrinsic motivation. Future research is warranted to leverage exergames as an enjoyable, motivating, and effective PA tool.

  18. A multicentre randomized/controlled trial of a conventional versus modestly accelerated radiotherapy in the laryngeal cancer: influence of a 1 week shortening overall time

    International Nuclear Information System (INIS)

    Hliniak, A.; Gwiazdowska, B.; Szutkowski, Z.; Kraszewska, E.; Kukolowicz, P.; Jarzabski, A.; Sochacka, B.; Mazurkiewicz, M.; Paprota, K.; Oliskiewicz, W.; Zadrozna, O.; Milecki, P.; Kubiak, M.; Czopkiewicz, L.; Jagas, M.; Gozdz, S.; Wieczorek, A.; Woytowicz, A.; Cisowska, B.; Magdziarz, H.; Nowakowski, S.; Kosniewski, W.; Laskosz, I.; Serafin, A.; Gradon, E.

    2002-01-01

    Background and purpose: To compare in a phase III study the loco-regional control, disease-free survival and overall survival induced by an accelerated regimen (AF) as compared with conventional regimen (CF) and to analyze the early and late post-radiation morbidity in both arms. Materials and methods: Patients with age≤75, WHO 0-1, suitable for a radical course of radiotherapy T1-T3, N0, M0, stage of glottic and supraglottic laryngeal cancer were randomized to either CF: 66Gy given in 33 fractions over 45 days or AF: 66Gy given in 33 fractions over 38 days (2 fractions every Thursday). A total of 395 patients were included from 05.1995 to 12.1998. Results. Early toxicity: At the end of radiotherapy patients treated with AF complained for more severe reactions than patients treated with CF. In 8 weeks after treatment completion patients treated with AF complained only for more severe pain on swallowing (P=0.027). In 4 months after treatment completion all types of toxicity except for skin teleangiectasia (P=0.001) were similar in the two groups. Loco-regional control: comparison between CF and AF showed no difference in terms of loco-regional control (P=0.37). Conclusions: The improvement in AF in terms of loco-regional control is estimated to be 3-5% in comparison with conventional regimen and is not significant. The intensity of reactions after 4 months was similar in both arms, what suggests the possibility of further shortening of the overall time by few days or enhancing the total dose within the limits of acceptable morbidity

  19. Manipulating Carbohydrate Availability Between Twice-Daily Sessions of High-Intensity Interval Training Over 2 Weeks Improves Time-Trial Performance.

    Science.gov (United States)

    Cochran, Andrew J; Myslik, Frank; MacInnis, Martin J; Percival, Michael E; Bishop, David; Tarnopolsky, Mark A; Gibala, Martin J

    2015-10-01

    Commencing some training sessions with reduced carbohydrate (CHO) availability has been shown to enhance skeletal muscle adaptations, but the effect on exercise performance is less clear. We examined whether restricting CHO intake between twice daily sessions of high-intensity interval training (HIIT) augments improvements in exercise performance and mitochondrial content. Eighteen active but not highly trained subjects (peak oxygen uptake [VO2peak] = 44 ± 9 ml/kg/min), matched for age, sex, and fitness, were randomly allocated to two groups. On each of 6 days over 2 weeks, subjects completed two training sessions, each consisting of 5 × 4-min cycling intervals (60% of peak power), interspersed by 2 min of recovery. Subjects ingested either 195 g of CHO (HI-HI group: ~2.3 g/kg) or 17 g of CHO (HI-LO group: ~0.3 g/kg) during the 3-hr period between sessions. The training-induced improvement in 250-kJ time trial performance was greater (p = .02) in the HI-LO group (211 ± 66 W to 244 ± 75 W) compared with the HI-HI group (203 ± 53 W to 219 ± 60 W); however, the increases in mitochondrial content was similar between groups, as reflected by similar increases in citrate synthase maximal activity, citrate synthase protein content and cytochrome c oxidase subunit IV protein content (p > .05 for interaction terms). This is the first study to show that a short-term "train low, compete high" intervention can improve whole-body exercise capacity. Further research is needed to determine whether this type of manipulation can also enhance performance in highly-trained subjects.

  20. Optimal Timing for Assessment of Tumor Response to Neoadjuvant Chemoradiation in Patients With Rectal Cancer: Do All Patients Benefit From Waiting Longer Than 6 Weeks?

    International Nuclear Information System (INIS)

    Perez, Rodrigo O.; Habr-Gama, Angelita; São Julião, Guilherme P.; Gama-Rodrigues, Joaquim; Sousa, Afonso H.S.; Campos, Fabio Guilherme; Imperiale, Antonio R.; Lynn, Patricio B.; Proscurshim, Igor; Nahas, Sergio Carlos; Ono, Carla Rachel; Buchpiguel, Carlos Alberto

    2012-01-01

    Purpose: To estimate the metabolic activity of rectal cancers at 6 and 12 weeks after completion of chemoradiation therapy (CRT) by 2-[fluorine-18] fluoro-2-deoxy-D-glucose-labeled positron emission tomography/computed tomography ([ 18 FDG]PET/CT) imaging and correlate with response to CRT. Methods and Materials: Patients with cT2-4N0-2M0 distal rectal adenocarcinoma treated with long-course neoadjuvant CRT (54 Gy, 5-fluouracil-based) were prospectively studied ( (ClinicalTrials.org) identifier (NCT00254683)). All patients underwent 3 PET/CT studies (at baseline and 6 and 12 weeks from CRT completion). Clinical assessment was at 12 weeks. Maximal standard uptake value (SUVmax) of the primary tumor was measured and recorded at each PET/CT study after 1 h (early) and 3 h (late) from 18 FDG injection. Patients with an increase in early SUVmax between 6 and 12 weeks were considered “bad” responders and the others as “good” responders. Results: Ninety-one patients were included; 46 patients (51%) were “bad” responders, whereas 45 (49%) patients were “good” responders. “Bad” responders were less likely to develop complete clinical response (6.5% vs. 37.8%, respectively; P=.001), less likely to develop significant histological tumor regression (complete or near-complete pathological response; 16% vs. 45%, respectively; P=.008) and exhibited greater final tumor dimension (4.3 cm vs. 3.3 cm; P=.03). Decrease between early (1 h) and late (3 h) SUVmax at 6-week PET/CT was a significant predictor of “good” response (accuracy of 67%). Conclusions: Patients who developed an increase in SUVmax after 6 weeks were less likely to develop significant tumor downstaging. Early-late SUVmax variation at 6-week PET/CT may help identify these patients and allow tailored selection of CRT-surgery intervals for individual patients.

  1. How stable are quantitative sensory testing measurements over time? Report on 10-week reliability and agreement of results in healthy volunteers

    Directory of Open Access Journals (Sweden)

    Nothnagel H

    2017-08-01

    Full Text Available Helen Nothnagel,1,2,* Christian Puta,1,3,* Thomas Lehmann,4 Philipp Baumbach,5 Martha B Menard,6,7 Brunhild Gabriel,1 Holger H W Gabriel,1 Thomas Weiss,8 Frauke Musial2 1Department of Sports Medicine and Health Promotion, Friedrich Schiller University, Jena, Germany; 2Department of Community Medicine, National Research Center in Complementary and Alternative Medicine, UiT, The Arctic University of Norway, Tromsø, Norway; 3Center for Interdisciplinary Prevention of Diseases Related to Professional Activities, 4Department of Medical Statistics, Computer Sciences and Documentation, Friedrich Schiller University, 5Department of Anesthesiology and Intensive Care Medicine, University Hospital Jena, Germany; 6Crocker Institute, Kiawah Island, SC, 7School of Integrative Medicine and Health Sciences, Saybrook University, Oakland, CA, USA; 8Department of Biological and Clinical Psychology, Friedrich Schiller University, Jena, Germany *These authors contributed equally to this work Background: Quantitative sensory testing (QST is a diagnostic tool for the assessment of the somatosensory system. To establish QST as an outcome measure for clinical trials, the question of how similar the measurements are over time is crucial. Therefore, long-term reliability and limits of agreement of the standardized QST protocol of the German Research Network on Neuropathic Pain were tested. Methods: QST on the lower back and hand dorsum (dominant hand were assessed twice in 22 healthy volunteers (10 males and 12 females; mean age: 46.6±13.0 years, with sessions separated by 10.0±2.9 weeks. All measurements were performed by one investigator. To investigate long-term reliability and agreement of QST, differences between the two measurements, correlation coefficients, intraclass correlation coefficients (ICCs, Bland–Altman plots (limits of agreement, and standard error of measurement were used. Results: Most parameters of the QST were reliable over 10 weeks in

  2. The relationship between low back pain and leisure time physical activity in a working population of cleaners - a study with weekly follow-ups for 1 year

    DEFF Research Database (Denmark)

    Jespersen, Tobias; Jorgensen, Marie B; Hansen, Jorgen V

    2012-01-01

    intensity in the subsequent 4 weeks. METHODS: 188 cleaners consented to participate in a 52-week text message survey about hours of LTPA and intensity of LBP (from 0 to 9) over the previous 7 days. The correlation between LBP and LTPA was calculated by Pearson correlation coefficient. During an episode...... and intensity of LBP measured on a weekly basis throughout a year showed no close correlation. Maintaining LTPA during an episode of acute LBP did not result in a positive effect on LBP in the following 4 weeks. Documentation of LTPA recommendations for acute LBP in working populations is still needed....... intensity difference between groups of 0.06; 95% confidence interval (95% CI) of 0.417 to 0.539) or higher probability of returning to initial pain level (Odds ratio 1,02; 95% CI of 0.50 to 2.09) in the following four weeks compared with cleaners decreasing LTPA during acute LBP. CONCLUSIONS: Hours of LTPA...

  3. Soft Robotics Week

    CERN Document Server

    Rossiter, Jonathan; Iida, Fumiya; Cianchetti, Matteo; Margheri, Laura

    2017-01-01

    This book offers a comprehensive, timely snapshot of current research, technologies and applications of soft robotics. The different chapters, written by international experts across multiple fields of soft robotics, cover innovative systems and technologies for soft robot legged locomotion, soft robot manipulation, underwater soft robotics, biomimetic soft robotic platforms, plant-inspired soft robots, flying soft robots, soft robotics in surgery, as well as methods for their modeling and control. Based on the results of the second edition of the Soft Robotics Week, held on April 25 – 30, 2016, in Livorno, Italy, the book reports on the major research lines and novel technologies presented and discussed during the event.

  4. Time-course investigation of infection with a low virulent Pasteurella multocida strain in normal and immune-suppressed 12-week-old free-range chickens

    DEFF Research Database (Denmark)

    Mbuthia, P.G.; Njagi, L.W.; Nyaga, P.N.

    2011-01-01

    Twelve-week-old indigenous chickens, either immune-suppressed using dexamethasone (IS) or non-immune-suppressed (NIS), were challenged with a low virulent strain, Pasteurella multocida strain NCTC 10322(T), and developed clinical signs and pathological lesions typical of chronic fowl cholera. NIS...

  5. a week in space

    Science.gov (United States)

    collette, christian

    2016-04-01

    COLLETTE Christian Institut Saint Laurent Liège Belgium. I am a science teacher at a technical high school. Generally, my students don't come from a privileged social background and are not particularly motivated for studies. For 10 years, I organize, for one of my sections, a spatial (and special) school year that ends in a spatial week. Throughout this year, with the help of my colleagues, I will introduce into all themes a lot of concepts relating to space. French, history, geography, English, mathematics, technical courses, sciences, and even gymnastics will be training actors in space culture. In spring, I will accompany my class in the Euro Space Center (Redu- Belgium) where we will live one week 24 hours on "like astronauts" One third of the time is dedicated to astronaut training (moonwalk, remote manipulator system, mission simulation, weightless wall, building rockets, satellites, etc.), One third to more intellectual activities on space (lectures, research, discovery of the outside run) the last one third of time in outside visits (museums, site of ESA-Redu) or in movies about space (October sky, Apollo 13, etc.) During this year, the profits, so educational as human, are considerable!

  6. ATLAS overview week highlights

    CERN Multimedia

    D. Froidevaux

    2005-01-01

    A warm and early October afternoon saw the beginning of the 2005 ATLAS overview week, which took place Rue de La Montagne Sainte-Geneviève in the heart of the Quartier Latin in Paris. All visitors had been warned many times by the ATLAS management and the organisers that the premises would be the subject of strict security clearance because of the "plan Vigipirate", which remains at some level of alert in all public buildings across France. The public building in question is now part of the Ministère de La Recherche, but used to host one of the so-called French "Grandes Ecoles", called l'Ecole Polytechnique (in France there is only one Ecole Polytechnique, whereas there are two in Switzerland) until the end of the seventies, a little while after it opened its doors also to women. In fact, the setting chosen for this ATLAS overview week by our hosts from LPNHE Paris has turned out to be ideal and the security was never an ordeal. For those seeing Paris for the first time, there we...

  7. 32-Week Holding-Time Study of SUMMA Polished Canisters and Triple Sorbent Traps Used To Sample Organic Constituents in Radioactive Waste Tank Vapor Headspace

    International Nuclear Information System (INIS)

    Evans, John C.; Huckaby, James L.; Mitroshkov, Alexandre V.; Julya, Janet L.; Hayes, James C.; Edwards, Jeffrey A.; Sasaki, Leela M.

    1997-01-01

    Two sampling methods[SUMMA polished canisters and triple sorbent traps (TSTs)] were compared for long-term storage of trace organic vapor samples collected from the headspaces of high-level radioactive waste tanks at the U.S. Department of Energy's Hanford Site in Washington State. Because safety, quality assurance, radiological controls, the long-term stability of the sampling media during storage needed to be addressed. Samples were analyzed with a gas chromatograph/mass spectrometer (GC/MS) using cryogenic reconcentration or thermal desorption sample introduction techniques. SUMMA canister samples were also analyzed for total non-methane organic compounds (TNMOC) by GC/flame ionization detector (FID) using EPA Compendium Method TO-12 . To verify the long-term stability of the sampling media, multiple samples were collected in parallel from a typical passively ventilated radioactive waste tank known to contain moderately high concentrations of both polar and nonpolar organic compounds. Analyses for organic analytes and TNMOC were conducted at increasing intervals over a 32-week period to determine whether any systematic degradation of sample integrity occurred. Analytes collected in the SUMMA polished canisters generally showed good stability over the full 32 weeks with recoveries at the 80% level or better for all compounds studied. The TST data showed some loss (50-80% recovery) for a few high-volatility compounds even in the refrigerated samples; losses for unrefrigerated samples were far more pronounced with recoveries as low as 20% observed in a few cases

  8. NOAA Coral Reef Watch Operational Near-real-time Twice-weekly Global 50 km Satellite Coral Bleaching Thermal Stress Monitoring Product Suite

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA Coral Reef Watch program produces a suite of near-real-time global 50 km monitoring products, based on sea surface temperature (SST) observations from NOAA's...

  9. Risk-adjusted survival for adults following in-hospital cardiac arrest by day of week and time of day: observational cohort study

    Science.gov (United States)

    Robinson, Emily J; Power, Geraldine S; Nolan, Jerry; Soar, Jasmeet; Spearpoint, Ken; Gwinnutt, Carl; Rowan, Kathryn M

    2016-01-01

    Background Internationally, hospital survival is lower for patients admitted at weekends and at night. Data from the UK National Cardiac Arrest Audit (NCAA) indicate that crude hospital survival was worse after in-hospital cardiac arrest (IHCA) at night versus day, and at weekends versus weekdays, despite similar frequency of events. Objective To describe IHCA demographics during three day/time periods—weekday daytime (Monday to Friday, 08:00 to 19:59), weekend daytime (Saturday and Sunday, 08:00 to 19:59) and night-time (Monday to Sunday, 20:00 to 07:59)—and to compare the associated rates of return of spontaneous circulation (ROSC) for >20 min (ROSC>20 min) and survival to hospital discharge, adjusted for risk using previously developed NCAA risk models. To consider whether any observed difference could be attributed to differences in the case mix of patients resident in hospital and/or the administered care. Methods We performed a prospectively defined analysis of NCAA data from 27 700 patients aged ≥16 years receiving chest compressions and/or defibrillation and attended by a hospital-based resuscitation team in response to a resuscitation (2222) call in 146 UK acute hospitals. Results Risk-adjusted outcomes (OR (95% CI)) were worse (p20 min 0.88 (0.81 to 0.95); hospital survival 0.72 (0.64 to 0.80)), and night-time (ROSC>20 min 0.72 (0.68 to 0.76); hospital survival 0.58 (0.54 to 0.63)) compared with weekday daytime. The effects were stronger for non-shockable than shockable rhythms, but there was no significant interaction between day/time of arrest and age, or day/time of arrest and arrest location. While many daytime IHCAs involved procedures, restricting the analyses to IHCAs in medical admissions with an arrest location of ward produced results that are broadly in line with the primary analyses. Conclusions IHCAs attended by the hospital-based resuscitation team during nights and weekends have substantially worse outcomes than during

  10. Risk-adjusted survival for adults following in-hospital cardiac arrest by day of week and time of day: observational cohort study.

    Science.gov (United States)

    Robinson, Emily J; Smith, Gary B; Power, Geraldine S; Harrison, David A; Nolan, Jerry; Soar, Jasmeet; Spearpoint, Ken; Gwinnutt, Carl; Rowan, Kathryn M

    2016-11-01

    Internationally, hospital survival is lower for patients admitted at weekends and at night. Data from the UK National Cardiac Arrest Audit (NCAA) indicate that crude hospital survival was worse after in-hospital cardiac arrest (IHCA) at night versus day, and at weekends versus weekdays, despite similar frequency of events. To describe IHCA demographics during three day/time periods-weekday daytime (Monday to Friday, 08:00 to 19:59), weekend daytime (Saturday and Sunday, 08:00 to 19:59) and night-time (Monday to Sunday, 20:00 to 07:59)-and to compare the associated rates of return of spontaneous circulation (ROSC) for >20 min (ROSC>20 min) and survival to hospital discharge, adjusted for risk using previously developed NCAA risk models. To consider whether any observed difference could be attributed to differences in the case mix of patients resident in hospital and/or the administered care. We performed a prospectively defined analysis of NCAA data from 27 700 patients aged ≥16 years receiving chest compressions and/or defibrillation and attended by a hospital-based resuscitation team in response to a resuscitation (2222) call in 146 UK acute hospitals. Risk-adjusted outcomes (OR (95% CI)) were worse (p20 min 0.88 (0.81 to 0.95); hospital survival 0.72 (0.64 to 0.80)), and night-time (ROSC>20 min 0.72 (0.68 to 0.76); hospital survival 0.58 (0.54 to 0.63)) compared with weekday daytime. The effects were stronger for non-shockable than shockable rhythms, but there was no significant interaction between day/time of arrest and age, or day/time of arrest and arrest location. While many daytime IHCAs involved procedures, restricting the analyses to IHCAs in medical admissions with an arrest location of ward produced results that are broadly in line with the primary analyses. IHCAs attended by the hospital-based resuscitation team during nights and weekends have substantially worse outcomes than during weekday daytimes. Organisational or care differences at

  11. The ATLAS Glasgow Overview Week

    CERN Multimedia

    Richard Hawkings

    2007-01-01

    The ATLAS Overview Weeks always provide a good opportunity to see the status and progress throughout the experiment, and the July week at Glasgow University was no exception. The setting, amidst the traditional buildings of one of the UK's oldest universities, provided a nice counterpoint to all the cutting-edge research and technology being discussed. And despite predictions to the contrary, the weather at these northern latitudes was actually a great improvement on the previous few weeks in Geneva. The meeting sessions comprehensively covered the whole ATLAS project, from the subdetector and TDAQ systems and their commissioning, through to offline computing, analysis and physics. As a long-time ATLAS member who remembers plenary meetings in 1991 with 30 people drawing detector layouts on a whiteboard, the hardware and installation sessions were particularly impressive - to see how these dreams have been translated into 7000 tons of reality (and with attendant cabling, supports and services, which certainly...

  12. My week: Marc Armour.

    Science.gov (United States)

    2017-03-11

    Marc Armour, is a fourth-year vet student at the Royal Veterinary College. Now on rotations, he chose to spend a week doing EMS with the BVA's journals, which are published by BMJ. Here's how he got on. British Veterinary Association.

  13. Phun Week: Understanding Physiology

    Science.gov (United States)

    Limson, Mel; Matyas, Marsha Lakes

    2009-01-01

    Topics such as sports, exercise, health, and nutrition can make the science of physiology relevant and engaging for students. In addition, many lessons on these topics, such as those on the cardiovascular, respiratory, and digestive systems, align with national and state life science education standards. Physiology Understanding Week (PhUn…

  14. CERN safety week

    CERN Multimedia

    DG Unit

    2009-01-01

    Following an increase in the number of accidents in 2008, the Safety Commission is organising a CERN safety week from 8 to 12 June for riders of bicycles, scooters and motorbikes. We invite you to take part in the programme, which will be held in the Main Building (Bldg. 500) and will consist of an exhibition, organised events and hands-on activities, including demonstrations of emergency braking, a driving simulator, simulation of what it feels like to drive under the influence of alcohol, demonstrations by the Fire Brigade, video projections, etc. There will also be a number of prizes to be won. Please sign up via your DSO.

  15. Photobook Week Aarhus 2017

    DEFF Research Database (Denmark)

    2017-01-01

    The discussions of the festival concentrated on distribution and markets. Using a regional axis, which mapped the Scandinavian practice in the global context, discussions were on themes related to publishing, distributing, buying, trading, and collecting photobooks. There was also a focus...... with UNSEEN Photobook Market in Amsterdam. The festival included a Dummy Doctoring Workshop, gallery talks, and the selection of shortlisted dummies from both the FotoBookFestival Kassel and the Nordic Dummy Award. Local and international booksellers offered the best from their shelves, and research based...... exhibitions were curated by Anne Elisabeth Toft (DK) and Claus Peder Pedersen (DK). As a special feature for Photobook Week Aarhus 2017, German collector and photo historian Thomas Wiegand curated an exhibition on the late German photographer Michael Schmidt’s photobooks, on shown at Aros Aarhus Art Museum....

  16. ATLAS Overview Week at Brookhaven

    CERN Multimedia

    Pilcher, J

    Over 200 ATLAS participants gathered at Brookhaven National Laboratory during the first week of June for our annual overview week. Some system communities arrived early and held meetings on Saturday and Sunday, and the detector interface group (DIG) and Technical Coordination also took advantage of the time to discuss issues of interest for all detector systems. Sunday was also marked by a workshop on the possibilities for heavy ion physics with ATLAS. Beginning on Monday, and for the rest of the week, sessions were held in common in the well equipped Berkner Hall auditorium complex. Laptop computers became the norm for presentations and a wireless network kept laptop owners well connected. Most lunches and dinners were held on the lawn outside Berkner Hall. The weather was very cooperative and it was an extremely pleasant setting. This picture shows most of the participants from a view on the roof of Berkner Hall. Technical Coordination and Integration issues started the reports on Monday and became a...

  17. Pregnancy Calendar: A Week-by-Week Guide

    Science.gov (United States)

    ... Fitness Diseases & Conditions Infections Drugs & Alcohol School & Jobs Sports Expert Answers (Q&A) Staying Safe Videos for Educators Search English Español A Week-by-Week Pregnancy Calendar KidsHealth / For Parents / A Week-by-Week ...

  18. Longer dialysis session length is associated with better intermediate outcomes and survival among patients on in-center three times per week hemodialysis: results from the Dialysis Outcomes and Practice Patterns Study (DOPPS).

    Science.gov (United States)

    Tentori, Francesca; Zhang, Jinyao; Li, Yun; Karaboyas, Angelo; Kerr, Peter; Saran, Rajiv; Bommer, Juergen; Port, Friedrich; Akiba, Takashi; Pisoni, Ronald; Robinson, Bruce

    2012-11-01

    Longer dialysis session length (treatment time, TT) has been associated with better survival among hemodialysis (HD) patients. The impact of TT on clinical markers that may contribute to this survival advantage is not well known. Using data from the international Dialysis Outcomes and Practice Patterns Study, we assessed the association of TT with clinical outcomes using both standard regression analyses and instrumental variable approaches. The study included 37,414 patients on in-center HD three times per week with prescribed TT from 120 to 420 min. Facility mean TT ranged from 214 min in the USA to 256 min in Australia-New Zealand. Accounting for country effects, mortality risk was lower for patients with longer TT {hazard ratio for every 30 min: all-cause mortality: 0.94 [95% confidence interval (CI): 0.92-0.97], cardiovascular mortality: 0.95 (95% CI: 0.91-0.98) and sudden death: 0.93 (95% CI: 0.88-0.98)}. Patients with longer TT had lower pre- and post-dialysis systolic blood pressure, greater intradialytic weight loss, higher hemoglobin (for the same erythropoietin dose), serum albumin and potassium and lower serum phosphorus and white blood cell counts. Similar associations were found using the instrumental variable approach, although the positive associations of TT with weight loss and potassium were lost. Favorable levels of a variety of clinical markers may contribute to the better survival of patients receiving longer TT. These findings support longer TT prescription in the setting of in-center, three times per week HD.

  19. A memorable week

    CERN Multimedia

    2012-01-01

    This has been a memorable week for CERN, starting with the award of a Special Fundamental Physics Prize and ending with the handover of the CERN Council Presidency from Michel Spiro to Agnieszka Zalewska. In between, the LHC team demonstrated its expertise with a successful pilot run with 25 nanosecond bunch spacing, a new application for Associate Membership was received, and we had good news on the budget.   The award of the Fundamental Physics Prize, and the manner in which it was divided between ATLAS, CMS and the LHC, is fitting recognition of the efforts of the thousands of people who have contributed over many years to the success of our flagship scientific endeavour. In making the award, the Milner Foundation aims to raise the profile of fundamental physics and its value to society. The Fundamental Physics Prize comes hot on the heels of the European Physical Society’s first Edison Volta Prize, which Sergio Bertolucci, Steve Myers and I were honoured to accept on behalf of t...

  20. At Least 39 Weeks

    Medline Plus

    Full Text Available ... It's been added to your dashboard . '; $("#video-display").html(data); $("title").append(_vidTitle + " | March of Dimes"); $("#main.container > em").append(_vidTitle); $("#vidTitle").html(_vidTitle); $("#vidDesc").html(_vidDesc); $("#vidDuration").html(convert_time(_ ...

  1. At Least 39 Weeks

    Medline Plus

    Full Text Available ... vidDesc").html(_vidDesc); $("#vidDuration").html(convert_time(_vidDuration)); var _videoId = queryString["id"]; relatedVidsDefer(_videoId).done(relatedVidsDetailsDefer, [mostPlayedVidsDefer(). ...

  2. Elective caesarean section at 38 weeks versus 39 weeks

    DEFF Research Database (Denmark)

    Glavind, Julie; Kindberg, S F; Uldbjerg, N

    2013-01-01

    To investigate whether elective caesarean section before 39 completed weeks of gestation increases the risk of adverse neonatal or maternal outcomes.......To investigate whether elective caesarean section before 39 completed weeks of gestation increases the risk of adverse neonatal or maternal outcomes....

  3. Effect of glatiramer acetate three-times weekly on the evolution of new, active multiple sclerosis lesions into T1-hypointense "black holes": a post hoc magnetic resonance imaging analysis.

    Science.gov (United States)

    Zivadinov, Robert; Dwyer, Michael; Barkay, Hadas; Steinerman, Joshua R; Knappertz, Volker; Khan, Omar

    2015-03-01

    Conversion of active lesions to black holes has been associated with disability progression in subjects with relapsing-remitting multiple sclerosis (RRMS) and represents a complementary approach to evaluating clinical efficacy. The objective of this study was to assess the conversion of new active magnetic resonance imaging (MRI) lesions, identified 6 months after initiating treatment with glatiramer acetate 40 mg/mL three-times weekly (GA40) or placebo, to T1-hypointense black holes in subjects with RRMS. Subjects received GA40 (n = 943) or placebo (n = 461) for 12 months. MRI was obtained at baseline and Months 6 and 12. New lesions were defined as either gadolinium-enhancing T1 or new T2 lesions at Month 6 that were not present at baseline. The adjusted mean numbers of new active lesions at Month 6 converting to black holes at Month 12 were analyzed using a negative binomial model; adjusted proportions of new active lesions at Month 6 converting to black holes at Month 12 were analyzed using a logistic regression model. Of 1,292 subjects with complete MRI data, 433 (50.3 %) GA-treated and 247 (57.2 %) placebo-treated subjects developed new lesions at Month 6. Compared with placebo, GA40 significantly reduced the mean number (0.31 versus 0.45; P = .0258) and proportion (15.8 versus 19.6 %; P = .006) of new lesions converting to black holes. GA significantly reduced conversion of new active lesions to black holes, highlighting the ability of GA40 to prevent tissue damage in RRMS.

  4. WBDOC Weekly Workload Status Report

    Data.gov (United States)

    Social Security Administration — Weekly reports of workloads processed in the Wilkes Barre Data Operation Center. Reports on quantities of work received, processed, pending and average processing...

  5. A busy week for Council

    CERN Multimedia

    2009-01-01

    This has been a busy week for the CERN Council, and there is much to report. Firstly, I’m pleased to say that Council approved the Organization’s Medium Term Plan, and with it the budget for financial year 2010. In a time of global recession, this is a strong vote of confidence from the Member States. This meeting of Council provided an opportunity for the working group on the scientific and geographical enlargement of CERN to set out a roadmap towards its final report, which is to be made at Council’s December session this year. One part of the process over the coming months is to bring the major players in particle physics from beyond the European region into the discussion, ensuring that the working group’s recommendations lead to an optimum position for CERN and European particle physics in the global context. An indicator of the continuing attractiveness of CERN is the fact that Council has received four new applications...

  6. Plant Operation: Work Week, Administration

    Science.gov (United States)

    Nation's Schools and Colleges, 1975

    1975-01-01

    A four-day work week for maintenance workers in the Jefferson County Public Schools in Lakewood, Colorado, reduces absenteeism and increases productivity; a basic manual for physical plant directors is reviewed. (Author/MLF)

  7. A week of Israeli restraint

    NARCIS (Netherlands)

    Reinhart, T.

    2006-01-01

    In Israeli discourse, Israel is always the side exercising restraint in its conflict with the Palestinians. This was true again for the events of the past week: As the Qassam rockets were falling on the Southern Israeli town of Sderot, it was “leaked” that the Israeli Minister of Defense had

  8. Astronomy Week in Madeira, Portugal

    Science.gov (United States)

    Augusto, P.; Sobrinho, J. L.

    2012-05-01

    The outreach programme Semanas da Astronomia (Astronomy Weeks) is held in late spring or summer on the island of Madeira, Portugal. This programme has been attracting enough interest to be mentioned in the regional press/TV/radio every year and is now, without doubt, the astronomical highlight of the year on Madeira. We believe that this programme is a good case study for showing how to attract the general public to astronomy in a small (population 250 000, area 900 km2) and fairly isolated place such as Madeira. Our Astronomy Weeks have been different each year and have so far included exhibitions, courses, talks, a forum, documentaries, observing sessions (some with blackouts), music and an astro party. These efforts may contribute towards putting Madeira on the map with respect to observational astronomy, and have also contributed to the planned installation of two observatories in the island.

  9. First week nutrition for broiler chickens

    OpenAIRE

    Lamot, David

    2017-01-01

    During the first week of life, broiler chickens undergo various developmental changes that are already initiated during incubation. Ongoing development of organs such as the gastro- intestinal tract and the immune system may affect the nutritional requirements during this age period. Despite the residual yolk that is available at hatch and that may provide nutritional support during the first days after hatch, the growth performance may be affected by the time in between hatch and first feed ...

  10. Nuclear Medicine week in Colombia

    International Nuclear Information System (INIS)

    Padhy, A.K.

    2003-01-01

    During the week of 6-12 October 2003 the IAEA organized a Research Coordination Meeting on 'Relationship between lower Respiratory Tract Infection, Gastroesophageal reflux and bronchial Asthma in children' at Hospital San Ignacio in Bogota. Besides there were four workshops in Bogota; workshops on Bone infection and Bone scan in Pediatric ortopaedics at Hospital Militar and Fundacion CardioInfantil, a workshop for Nuclear Medicine Technologists and a workshop on Sentinel Lymph Node mapping and Surgical Gamma Probe Application at Institute of Oncology. A nuclear cardiology workshop was organized in Medellin, and finally crowning them all was the 9th Congress of the Colombian Association of Nuclear Medicine at Cali from 10-12 October, 2003; probably the largest and best Colombian nuclear medicine congress every held in the country. A workshop was also organized in Cali for nuclear medicine technologists in conjunction with the Annual Convention. It was a mix of IAEA's Technical Cooperation and Regular Budget activities along with the activities of Colombian Association of Nuclear Medicine, bringing in absolute synergy to galvanize the entire nuclear medicine community of the country. The week saw nuclear medicine scientists from more than 20 IAEA Member States converging on Colombia to spread the message of nuclear medicine, share knowledge and to foster International understanding and friendship among the nuclear medicine people of the world

  11. Cutaneous reaction associated with weekly docetaxel administration.

    Science.gov (United States)

    Chew, Lita; Chuen, Vivianne Shih Lee

    2009-03-01

    Docetaxel-based chemotherapy will remain clinically relevant and many of our patients will continue to receive the drug. In a recent phase 2 study of docetaxel 35 mg/m2 (weekly) in patients with metastatic breast cancer, the incidence of grade 3 cutaneous toxicity is 19%. The skin toxicity observed consists of limb/palmar-plantar erythematous reactions, or fixed-plaque erythrodysesthesia. Case series or reports have reported varied manifestations of skin reactions and include erythema multiforme, nail changes (onycholysis, pigmentation, paronychia), scleroderma, supravenous discoloration, radiation recall dermatitis, and flagellate erythema. We would like to report four patients with cutaneous reactions resulting from weekly administration of docetaxel. All cases are heavily pre-treated patients, receiving docetaxel as second or third line therapy. The cutaneous reactions occur at cycle 5. The time between chemotherapy to development of skin lesions is from 1 to 7 days. Lesions usually resolve with desquamation leaving behind areas with hyper-pigmentation or hypo-pigmentation over a period of 2 to 3 weeks. The management strategies include hand elevation, warm or cold compresses, topical and/or systemic antibiotics, topical and/or systemic corticosteroids, and cessation of drug. There is a need for a systematic approach to manage these cutaneous reactions. Oncology trained pharmacists play vital roles in assessing, managing, documenting and patient education.

  12. Revisiting tropical instability wave variability in the Atlantic ocean using SODA reanalysis

    Science.gov (United States)

    de Decco, Hatsue Takanaca; Torres Junior, Audalio Rebelo; Pezzi, Luciano Ponzi; Landau, Luiz

    2018-03-01

    The spatial and temporal variability of energy exchange in Tropical Instability Waves (TIWs) in the Atlantic Ocean were investigated. A spectral analysis was used to filter the 5-day mean results from Simple Ocean Data Assimilation (SODA) reanalysis spanning from 1958 to 2008. TIWs were filtered over periods of 15 to 60 days and between wavelengths of 4 and 20 longitude degrees. The main approach of this study was the use of bidirectionally filtered TIW time series as the perturbation fields, and the difference in these time series from the SODA total results was considered to be the basic state for energetics analysis. The main result was that the annual cycle (period of 360 days) was the main source of variability of the waves, and the semi-annual cycle (period of 180 days) was a secondary variation, which indicated that TIWs occurred throughout the year but with intensity that varies seasonally. In SODA, barotropic instability acts as the mechanism that feeds and extracts energy to/from TIWs at equatorial Atlantic. Baroclinic instability is the main mechanism that extracts energy from TIWs to the equatorial circulation north of the Equator. All TIW patterns of variability were observed western of 10° W. The present study reveals new evidences regarding TIW variability and suggests that future investigations should include a detailed description of TIW dynamics as part of Atlantic Ocean equatorial circulation.

  13. "Mid-Week Pictorial": Pioneer American Photojournalism Magazine.

    Science.gov (United States)

    Kenney, Keith

    In 1914 (22 years before the inception of "Life" magazine), the "New York Times" began publishing "Mid-Week Pictorial" to absorb a flood of war pictures pouring in from Europe. Several sociological and technological forces shaped "Mid-Week Pictorial" as a pioneer of American photojournalism magazines,…

  14. The Four Day School Week. Research Brief

    Science.gov (United States)

    Muir, Mike

    2013-01-01

    Can four-day school weeks help districts save money? How do districts overcome the barriers of moving to a four-day week? What is the effect of a four-day week on students, staff and the community? This paper enumerates the benefits for students and teachers of four-day school weeks. Recommendations for implementation of a four-day week are also…

  15. Randomized pharmacokinetic evaluation of different rifabutin doses in African HIV- infected tuberculosis patients on lopinavir/ritonavir-based antiretroviral therapy.

    Science.gov (United States)

    Naiker, Suhashni; Connolly, Cathy; Wiesner, Lubbe; Kellerman, Tracey; Reddy, Tarylee; Harries, Anthony; McIlleron, Helen; Lienhardt, Christian; Pym, Alexander

    2014-11-19

    Pharmacokinetic interactions between rifampicin and protease inhibitors (PIs) complicate the management of HIV-associated tuberculosis. Rifabutin is an alternative rifamycin, for patients requiring PIs. Recently some international guidelines have recommended a higher dose of rifabutin (150 mg daily) in combination with boosted lopinavir (LPV/r), than the previous dose of rifabutin (150 mg three times weekly {tiw}). But there are limited pharmacokinetic data evaluating the higher dose of rifabutin in combination with LPV/r. Sub-optimal dosing can lead to acquired rifamycin resistance (ARR). The plasma concentration of 25-O-desacetylrifabutin (d-RBT), the metabolite of rifabutin, increases in the presence of PIs and may lead to toxicity. Sixteen patients with TB-HIV co-infection received rifabutin 300 mg QD in combination with tuberculosis chemotherapy (initially pyrazinamide, isoniazid and ethambutol then only isoniazid), and were then randomized to receive isoniazid and LPV/r based ART with rifabutin 150 mg tiw or rifabutin 150 mg daily. The rifabutin dose with ART was switched after 1 month. Serial rifabutin and d-RBT concentrations were measured after 4 weeks of each treatment. The median AUC0-48 and Cmax of rifabutin in patients taking 150 mg rifabutin tiw was significantly reduced compared to the other treatment arms. Geometric mean ratio (90% CI) for AUC0-48 and Cmax was 0.6 (0.5-0.7) and 0.5 (0.4-0.6) for RBT 150 mg tiw compared with RBT 300 mg and 0.4 (0.4-0.4) and 0.5 (0.5-0.6) for RBT 150 mg tiw compared with 150 mg daily. 86% of patients on the tiw rifabutin arm had an AUC0-24 ART, and grade 3 neutropenia (asymptomatic) was reported in 4 patients. These events were not associated with increases in rifabutin or metabolite concentrations. A daily 150 mg dose of rifabutin in combination with LPV/r safely maintained rifabutin plasma concentrations in line with those shown to prevent ARR. ClinicalTrials.gov Identifier: NCT00640887.

  16. 23 CFR 635.118 - Payroll and weekly statements.

    Science.gov (United States)

    2010-04-01

    ... CONSTRUCTION AND MAINTENANCE Contract Procedures § 635.118 Payroll and weekly statements. For all projects... contract provisions for the project, are to be retained by the STD for the time period pursuant to 49 CFR...

  17. Fire Pumps: Time to Change NFPA 25 Weekly Churn Testing

    Science.gov (United States)

    Saidi, John F.; Davis, Richard J.

    2010-01-01

    APPA, through its Code Advocacy Task Force (CATF), is active with code organizations such as the National Fire Protection Association (NFPA). This article reviews some of the recent work on NFPA 25, Standard for the Inspection, Testing, and Maintenance of Water-Based Fire Protection Systems, by the CATF and some members of the NFPA 25 Technical…

  18. Defect engineering in 1D Ti-W oxide nanotube arrays and their correlated photoelectrochemical performance.

    Science.gov (United States)

    Abdelhafiz, Ali A; Ganzoury, Mohamed A; Amer, Ahmad W; Faiad, Azza A; Khalifa, Ahmed M; AlQaradawi, Siham Y; El-Sayed, Mostafa A; Alamgir, Faisal M; Allam, Nageh K

    2018-04-18

    Understanding the nature of interfacial defects of materials is a critical undertaking for the design of high-performance hybrid electrodes for photocatalysis applications. Theoretical and computational endeavors to achieve this have touched boundaries far ahead of their experimental counterparts. However, to achieve any industrial benefit out of such studies, experimental validation needs to be systematically undertaken. In this sense, we present herein experimental insights into the synergistic relationship between the lattice position and oxidation state of tungsten ions inside a TiO2 lattice, and the respective nature of the created defect states. Consequently, a roadmap to tune the defect states in anodically-fabricated, ultrathin-walled W-doped TiO2 nanotubes is proposed. Annealing the nanotubes in different gas streams enabled the engineering of defects in such structures, as confirmed by XRD and XPS measurements. While annealing under hydrogen stream resulted in the formation of abundant Wn+ (n < 6) ions at the interstitial sites of the TiO2 lattice, oxygen- and air-annealing induced W6+ ions at substitutional sites. EIS and Mott-Schottky analyses indicated the formation of deep-natured trap states in the hydrogen-annealed samples, and predominantly shallow donating defect states in the oxygen- and air-annealed samples. Consequently, the photocatalytic performance of the latter was significantly higher than those of the hydrogen-annealed counterparts. Upon increasing the W content, photoelectrochemical performance deteriorated due to the formation of WO3 crystallites that hindered charge transfer through the photoanode, as evident from the structural and chemical characterization. To this end, this study validates the previous theoretical predictions on the detrimental effect of interstitial W ions. In addition, it sheds light on the importance of defect states and their nature for tuning the photoelectrochemical performance of the investigated materials.

  19. Lack of generalizability of observational studies' findings for turnover time reduction and growth in surgery based on the State of Iowa, where from one year to the next, most growth was attributable to surgeons performing only a few cases per week.

    Science.gov (United States)

    Dexter, Franklin; Jarvie, Craig; Epstein, Richard H

    2018-02-01

    Three observational studies at large teaching hospitals found that reducing turnover times resulted in the surgeons performing more cases. We sought to determine if these findings are generalizable to other hospitals, because, if so, reducing turnover times may be an important mechanism for hospitals to use for growing caseloads. Observational cohort study. 116 hospitals in Iowa with inpatient or outpatient surgery from July 1, 2013 through June 30, 2015. Surgeons in Iowa, each with a unique identifier among hospitals. The independent variable was the number of inpatient and outpatient cases that each surgeon performed each week during the first fiscal year beginning July 1, 2013. The dependent variables were surgeons' number of inpatient and outpatient surgical cases, and intraoperative work relative value units (RVU's) for outpatient cases, during the second fiscal year. The average hospital in Iowa had less than half of its growth from year 1 to year 2 in numbers of cases among surgeons who performed >2 cases per week in the baseline year (23.0%±2.5% [SE], P2 cases per week at other hospitals in the state during that year (24.4%±2.6%, P<0.0001). Less than half the growth in RVU's was among those surgeons (21.3%±2.5%, P<0.0001). Most (≥50%) annual growth in surgery, both based on the number of total inpatient and outpatient surgical cases, and on the total outpatient RVU's, was attributable to surgeons who performed 2 or fewer cases per week at each hospital statewide during the preceding year. Therefore, the strategic priority should be to assure that the many low-caseload surgeons have access to convenient OR time (e.g., by allocating sufficient OR time, and assigning surgeon blocks, in a mathematically sound, evidence-based way). Although reducing turnover times and anesthesia-controlled times to promote growth will be beneficial for a few surgeons, the effect on total caseload will be small. Copyright © 2017 Elsevier Inc. All rights reserved.

  20. 78 FR 69749 - American Education Week, 2013

    Science.gov (United States)

    2013-11-20

    ... Education Week offers a chance to express our gratitude to educators across our Nation. Let us do so with a... Education Week, 2013 #0; #0; #0; Presidential Documents #0; #0; #0;#0;Federal Register / Vol. 78 , No. 224...

  1. Understanding Infidelity: An Interview with Gerald Weeks

    Science.gov (United States)

    Smith, Travis

    2011-01-01

    In this interview, Gerald Weeks shares his expertise on the topic of infidelity and couples counseling. Dr. Weeks defines infidelity, presents assessment strategies for treating the issue of infidelity, and discusses an intersystemic model for infidelity treatment when counseling couples. Dr. Weeks also provides insight into common mistakes made…

  2. Bilateral hip arthroplasty: is 1-week staging the optimum strategy?

    Directory of Open Access Journals (Sweden)

    Willis-Owen Charles A

    2010-11-01

    Full Text Available Abstract Seventy-nine patients underwent bilateral hip arthroplasty staged either at 1 week (Group 1 or after greater intervals (as suggested by the patients, mean 44 weeks, range 16-88 weeks (Group 2, over a five year period at one Institution. Sixty-eight patients (29 bilateral hip resurfacings and 39 total hip replacements completed questionnaires regarding their post-operative recovery, complications and overall satisfaction with the staging of their surgery. There was no significant age or ASA grade difference between the patient groups. Complication rates in the two groups were similar and overall satisfaction rates were 84% in Group 1 (n = 32 and 89% in Group 2 (n = 36. Cumulative hospital lengths of stay were significantly longer in Group 1 patients (11.9 days vs 9.1 days(p The mean time to return to part-time work was 16.4 weeks for Group 1, and a cumulative 17.2 weeks (8.8 and 8.4 weeks for Group 2. The time to return to full-time work was significantly shorter for Group 1 patients (21.0 weeks, compared with a cumulative 29.7 weeks for Group 2(p Hip resurfacing patients in Group 2 had significantly shorter durations of postoperative pain and were able to return to part-time and full time work sooner than total hip arthroplasty patients. There was a general trend towards a faster recovery and resumption of normal activities following the second operation in Group 2 patients, compared with the first operation. Bilateral hip arthroplasty staged at a 1-week interval resulted in an earlier resolution of hip pain, and an earlier return to full-time work (particularly following total hip replacement surgery, with high levels of patient satisfaction and no increased risk in complications; however the hospital length of stay was significantly longer. The decision for the timing of staged bilateral surgery should be made in conjunction with the patient, making adjustments to accommodate their occupational needs and functional demands.

  3. Regularity and irreversibility of weekly travel behavior

    NARCIS (Netherlands)

    Kitamura, R.; van der Hoorn, A.I.J.M.

    1987-01-01

    Dynamic characteristics of travel behavior are analyzed in this paper using weekly travel diaries from two waves of panel surveys conducted six months apart. An analysis of activity engagement indicates the presence of significant regularity in weekly activity participation between the two waves.

  4. Celebrating partnerships for International Development Week 2018 ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    2018-01-31

    Jan 31, 2018 ... International Development Week, observed February 4-10 this year, is an opportunity to focus on Canada's contributions ... This event is part of the 2018 International Development Week conference at the University of Ottawa. ... Call for new OWSD Fellowships for Early Career Women Scientists now open.

  5. Practice It: Create a Weekly Activity Plan

    Science.gov (United States)

    At the beginning of the week, create an activity plan to help you reach your goals. Start by identifying your goals for the week. Based on your goals, write down when you are going to exercise and what you are going to do.

  6. 30 CFR 75.364 - Weekly examination.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Weekly examination. 75.364 Section 75.364... MANDATORY SAFETY STANDARDS-UNDERGROUND COAL MINES Ventilation § 75.364 Weekly examination. (a) Worked-out... bleeder system. (b) Hazardous conditions. At least every 7 days, an examination for hazardous conditions...

  7. 77 FR 42941 - Captive Nations Week, 2012

    Science.gov (United States)

    2012-07-20

    ..., 2012 Captive Nations Week, 2012 By the President of the United States of America A Proclamation When... unbreakable bonds endure. During Captive Nations Week, America renews our abiding ties to all peoples who... sound the call for reform. We see the same fierce hope in those who defy censorship and reach beyond an...

  8. Just one week 'til GridWorld

    CERN Multimedia

    Harris, Derrick

    2006-01-01

    "Here we are, one week from GridWorld, and I can feel the pressure rising. Although the news has been a little slow recently, I know that won't last long, and between next week and mid-November, I have a feelling I'll have heard from just about every vendor and organization in the Grid space." (1 page)

  9. A double Weekly Bulletin over Easter

    CERN Multimedia

    2004-01-01

    During the Easter period, the weeks of 12 and 19 April, there will be only one issue of the Weekly Bulletin (no. 16-17/2004). Announcements for publication in the next issue (no. 18/2004) should be sent on Tuesday 20 April midday at the latest. Publication Section Tel. 79971

  10. National Poison Prevention Week Promotional Materials.

    Science.gov (United States)

    Poison Prevention Week Council, Washington, DC.

    This collection of materials for parents, early childhood workers, the elderly, and anyone in situations requiring safeguards against poisoning, spans the years 1993 and 1994 and is intended to promote National Poison Prevention Week. The materials included are: (1) the 31-page, illustrated report on National Poison Prevention Week for 1993,…

  11. WEEKLY BULLETIN : WE ARE INTERESTED IN YOUR OPINION !

    CERN Multimedia

    2002-01-01

    The Weekly Bulletin publication team has prepared a questionnaire that finally allows you to say all you think, good or bad, about CERN's in-house journal. The aim of this survey is to improve the Bulletin and make it more readable and more practical. In short, we want it to be more useful to you! We will be publishing the results of this survey in a few weeks' time. Between now and then we invite you to fill out the web form, or the form just before the last page of this issue. Just 5 minutes of your time!

  12. Vehicle Technologies Fact of the Week 2015

    Energy Technology Data Exchange (ETDEWEB)

    Davis, Stacy C. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Diegel, Susan W. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Moore, Sheila A. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Boundy, Robert G. [Roltek, Inc., Clinton, TN (United States)

    2016-05-01

    Each week the U.S. Department of Energy s Vehicle Technology Office (VTO) posts a Fact of the Week on their website: http://www1.eere.energy.gov/vehiclesandfuels/ . These Facts provide statistical information, usually in the form of charts and tables, on vehicle sales, fuel economy, gasoline prices, and other transportation-related trends. Each Fact is a stand-alone page that includes a graph, text explaining the significance of the data, the supporting information on which the graph was based, and the source of the data. A link to the current week s Fact is available on the VTO homepage, but older Facts (back to 2009) are archived and still available at: http://energy.gov/eere/vehicles/current-and-past-years-facts-week. Each Fact of the Week website page includes a link to an Excel file. That file contains the data from the Supporting Information section of the page so that researchers can easily use data from the Fact of the Week in their work. Beginning in August of 2015, a subscription list is available on the DOE website so that those interested can sign up for an email to be sent each Monday which includes the text and graphic from the current week s Fact. This report is a compilation of the Facts that were posted during calendar year 2015. The Facts were created, written and prepared by staff in Oak Ridge National Laboratory's Center for Transportation Analysis.

  13. Weekly variability of surface CO concentrations in Moscow

    Science.gov (United States)

    Sitnov, S. A.; Adiks, T. G.

    2014-03-01

    Based on observations of carbon monoxide (CO) concentrations at three Mosekomonitoring stations, we have analyzed the weekly cycle of CO in the surface air of Moscow in 2004-2007. At all stations the minimum long-term mean daily CO values are observed on Sunday. The weekly cycle of CO more clearly manifests itself at the center of Moscow and becomes less clear closer to the outskirts. We have analyzed the reproducibility of the weekly cycle of CO from one year to another, the seasonal dependence, its specific features at different times of day, and the changes in the diurnal cycle of CO during the week. The factors responsible for specific features of the evolution of surface CO concentrations at different observation stations have been analyzed. The empirical probability density functions of CO concentrations on weekdays and at week- end are presented. The regularity of the occurrence of the weekend effect in CO has been investigated and the possible reasons for breaks in weekly cycles have been analyzed. The Kruskal-Wallis test was used to study the statistical significance of intraweek differences in surface CO contents.

  14. 78 FR 71431 - National Family Week, 2013

    Science.gov (United States)

    2013-11-27

    ..., same-sex couple, single parent, or guardian--families are the building blocks of American society... Family Week, 2013 #0; #0; #0; Presidential Documents #0; #0; #0;#0;Federal Register / Vol. 78 , No. 229...

  15. The Weekly Structure of US Stock Prices

    OpenAIRE

    Guglielmo Maria Caporale; Luis A. Gil-Alana

    2010-01-01

    In this paper we use fractional integration techniques to examine the degree of integration of four US stock market indices, namely the Standard and Poor, Dow Jones, Nasdaq and NYSE, at a daily frequency from January 2005 till December 2009. We analyse the weekly structure of the series and investigate their characteristics depending on the specific day of the week. The results indicate that the four series are highly persistent; a small degree of mean reversion (i.e., orders of integration s...

  16. Teaching Crossroads: 8th IPB Erasmus Week

    OpenAIRE

    Silva, Elisabete Mendes (Ed.); Pais, Clarisse (Ed.); Pais, L.S. (Ed.)

    2013-01-01

    We are proud to present the second number of Teaching Crossroads, within the 8th IPB Erasmus week which took place in May 2012. This publication is the result of the papers delivered during our Erasmus Week that is becoming increasingly popular among teaching and non-teaching staff from several Erasmus partner Universities. Similarly to last year, we are continuing the publication of Teaching Crossroads whose main purpose is to reach students and teaching staff of the IPB...

  17. A double Weekly Bulletin over Easter

    CERN Multimedia

    2004-01-01

    During the Easter period, the weeks of 12 and 19 April, there will be only one issue of the Weekly Bulletin (no. 16-17/2004). Items for publication in this double issue should reach the Publication section or Staff Association, as appropriate, before midday on Tuesday 6 April. Announcements for publication in the next issue (no. 18/2004) should be sent on Tuesday 20 April midday at the latest. Publication Section Tel. 79971

  18. Special Relativity in Week One: 3) Introducing the Lorentz Contraction

    Science.gov (United States)

    Huggins, Elisha

    2011-01-01

    This is the third of four articles on teaching special relativity in the first week of an introductory physics course. With Einstein's second postulate that the speed of light is the same to all observers, we could use the light pulse clock to introduce time dilation. But we had difficulty introducing the Lorentz contraction until we saw the movie…

  19. A phase II randomized trial comparing radiotherapy with concurrent weekly cisplatin or weekly paclitaxel in patients with advanced cervical cancer

    International Nuclear Information System (INIS)

    Geara, Fady B; Shamseddine, Ali; Khalil, Ali; Abboud, Mirna; Charafeddine, Maya; Seoud, Muhieddine

    2010-01-01

    This is a prospective comparison of weekly cisplatin to weekly paclitaxel as concurrent chemotherapy with standard radiotherapy for locally advanced cervical carcinoma. Between May 2000 and May 2004, 31 women with FIGO stage IB2-IVA cervical cancer or with postsurgical pelvic recurrence were enrolled into this phase II study and randomized to receive on a weekly basis either 40 mg/m 2 Cisplatin (group I; 16 patients) or 50 mg/m 2 paclitaxel (group II; 15 patients) concurrently with radiotherapy. Median total dose to point A was 74 Gy (range: 66-92 Gy) for group I and 66 Gy (range: 40-98 Gy) for group II. Median follow-up time was 46 months. Patient and tumor characteristics were similar in both groups. The mean number of chemotherapy cycles was also comparable with 87% and 80% of patients receiving at least 4 doses in groups I and II, respectively. Seven patients (44%) of group I and 8 patients (53%) of group II developed tumor recurrence. The Median Survival time was not reached for Group I and 53 months for group II. The proportion of patients surviving at 2 and 5 years was 78% and 54% for group I and 73% and 43% for group II respectively. This small prospective study shows that weekly paclitaxel does not provide any clinical advantage over weekly cisplatin for concurrent chemoradiation for advanced carcinoma of the cervix

  20. Motor cortical adaptations to 2 weeks of lower limb immobilization

    DEFF Research Database (Denmark)

    Jensen, Jesper Lundbye; Christensen, Mark Schram; Petersen, Tue Hvass

    was to examine the effect of 2 weeks of immobilization on corticospinal excitability using transcranial magnetic stimulation (TMS) and to investigate blood flow changes in the sensorimotor cortex during ankle movement using functional magnetic resonance imaging (fMRI). 12 healthy volunteers had the left ankle...... and foot immobilized by a cast for 2 weeks. TMS and fMRI testing was performed on 2 separate days before immobilization, on the day of cast removal and 2 weeks of recovery. fMRI was accomplished with a Siemens Trio 3T scanner and fMRI time series were obtained during both active and passive ankle movement...... in a block design alternating between movement (20s) and rest (20s). Ankle joint position, torque and the EMG activity from m. soleus and m. tibialis anterior were monitored throughout all measurements. Following immobilization maximal voluntary plantarflexion and dorsiflexion torque decreased by 15% and 22...

  1. Vehicle Technologies Fact of the Week 2013

    Energy Technology Data Exchange (ETDEWEB)

    Davis, Stacy Cagle [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Williams, Susan E. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Moore, Sheila A. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Boundy, Robert Gary [Roltek, Inc., Clinton, TN (United States)

    2014-03-01

    Each week the U.S. Department of Energy s Vehicle Technology Office (VTO) posts a Fact of the Week on their website: http://www1.eere.energy.gov/vehiclesandfuels/ . These Facts provide statistical information, usually in the form of charts and tables, on vehicle sales, fuel economy, gasoline prices, and other transportation-related trends. Each Fact is a stand-alone page that includes a graph, text explaining the significance of the data, the supporting information on which the graph was based, and the source of the data. A link to the current week s Fact is available on the VTO homepage, but older Facts are archived and still available at: http://www1.eere.energy.gov/vehiclesandfuels/facts/. This report is a compilation of the Facts that were posted during calendar year 2013. The Facts were written and prepared by staff in Oak Ridge National Laboratory's Center for Transportation Analysis.

  2. Metabolic Response to Four Weeks of Muscular Endurance Resistance Training

    Directory of Open Access Journals (Sweden)

    John W. Farrell III

    2017-10-01

    Full Text Available Background: Previous investigations have shown that muscular endurance resistance training (MERT is conducive in improving the onset of blood lactate accumulation (OBLA. However, the metabolic response and time course for adaption is still unclear. Objective: The aims of the current study were to evaluate and track the metabolic response to an individual session of MERT as well as to assess performance adaptations of supplementing an aerobic exercise training program with four weeks of MERT. Methods: Seventeen aerobically active men were randomly assigned to either the experimental (EX or control group (CON, 9 EX and 8 CON. Baseline measures included a graded exercise test (GXT and 1-repetition maximum (1RM testing for leg press (LP, leg curl (LC, and leg extension (LE. CON continued their regular aerobic activity while the EX supplemented their regular aerobic exercise with 4 weeks of MERT. Results: No significant group differences were observed for all pre-training variables. Following four weeks of training no significant differences in cardiorespiratory or metabolic variables were observed for either group. However, significant improvements in LC and LE 1-RM were observed in EX compared to CON. Substantial accumulations in blood lactate were observed following each MERT session. Conclusion: Four weeks of MERT did not improve cardiorespiratory or metabolic variables, but did significantly improve LC and LE. MERT was also observed to induce a blood lactate response similar to that of HIIT. These findings suggest greater than four weeks is need to see metabolic adaptations conducive for improved aerobic performance using MERT.

  3. Immunochemotherapy with interleukin-2, interferon- α and 5-fluorouracil for progressive metastatic renal cell carcinoma: a multicenter phase II study

    Science.gov (United States)

    Herpen, C M L van; Jansen, R L H; Kruit, W H J; Hoekman, K; Groenewegen, G; Osanto, S; Mulder, P H M De

    2000-01-01

    In patients with metastatic renal cell carcinoma response rates of 7–26% have been achieved with immunotherapy. A high response rate of 48% in 35 patients has been reported for treatment with the combination of interferon-α (IFN-α), interleukin-2 (IL-2) and 5-fluorouracil (5-FU) (Atzpodien et al (1993 a) Eur J Cancer29A: S6–8). We conducted a multicentre phase II study to confirm these results. Metastatic renal cell carcinoma patients were treated as outpatients with an 8-week treatment cycle. Recombinant human IL-2 20 MU m−2was administered subcutaneously (s.c.) three times a week (t.i.w) in weeks 1 and 4 and 5 MU m−2t.i.w. in weeks 2 and 3. Recombinant human IFN-α 2a 6 MU m−2was administered s.c. once in weeks 1 and 4 and t.i.w. in weeks 2 and 3, and 9 MU m−2t.i.w. in weeks 5–8. 5-FU (750 mg m−2) was given as a bolus injection intravenous once a week in weeks 5–8. The treatment cycle was repeated once in case of response or minor response. Fifty-two patients entered the study. All had undergone a nephrectomy and had progressive metastatic disease. The median WHO-performance status was 1, the median number of metastatic sites was 2 (range 1–5) and the median time between the diagnosis of the primary tumour and the start of treatment was 12.9 months (range 1–153). Among the 51 patients, including four patients with early progressive disease, who were evaluable for response, the response rate was 11.8% (95% confidence interval (CI) 2.9–20.7%), with no complete responses. Median duration of response was 8.3 (range 3.8–22.4+) months. Median survival was 16.5 (range 1.8–30.5+) months. Grade 3/4 toxicity (WHO) occurred in 29/52 (55.8%) of the patients in cycle 1 and in 6/16 (37.5%) of the patients in cycle 2. It consisted mainly of anorexia, fatigue, nausea, fever and leucocytopenia. We cannot confirm the high response rate in patients with metastatic renal cell carcinoma treated with the combination of IFN-α, IL-2 and 5-FU, as described

  4. 78 FR 30729 - World Trade Week, 2013

    Science.gov (United States)

    2013-05-22

    ... ways we can do that is by boosting manufacturing and expanding trade that allows us to sell more of our..., high-standard trade agreement: the Trans-Pacific Partnership. Once realized, the deal would boost our... creates jobs and grows our economy. During World Trade Week, we recognize workers, growers, and...

  5. First week nutrition for broiler chickens

    NARCIS (Netherlands)

    Lamot, David

    2017-01-01

    During the first week of life, broiler chickens undergo various developmental changes that are already initiated during incubation. Ongoing development of organs such as the gastro- intestinal tract and the immune system may affect the nutritional requirements during this age period. Despite the

  6. 76 FR 22001 - National Park Week, 2011

    Science.gov (United States)

    2011-04-20

    .... America is fortunate to have a long history of conservation pioneers, like President Theodore Roosevelt... National Park Week, 2011 By the President of the United States of America A Proclamation Every day, America... and vitality of all Americans. In no place is America's natural and historic legacy more evident than...

  7. 76 FR 63801 - Fire Prevention Week, 2011

    Science.gov (United States)

    2011-10-13

    ... Proclamation Fires, whether caused by people or nature, can have devastating effects. Hundreds of thousands of... practice fire safety throughout the year. This year's Fire Prevention Week theme, ``Protect Your Family... mowing dry grasses to two inches or less, and by clearing brush, leaves, green grass, and lumber from...

  8. 77 FR 22177 - National Volunteer Week, 2012

    Science.gov (United States)

    2012-04-12

    ..., service and social innovation will play an essential role in achieving our highest ambitions--from a world-class education for every child to an economy built to last. During National Volunteer Week, we pay... landmark national service law that laid out a strategy to link service with innovation, established the...

  9. 75 FR 29393 - Small Business Week, 2010

    Science.gov (United States)

    2010-05-26

    ..., and gives entrepreneurs the security they need to innovate and take risks. We have also enacted new... year's State of the Union address, I proposed creating a $30 billion lending fund to help increase the... small business owners acquire loans and hire workers. This week, we celebrate the role of entrepreneurs...

  10. 75 FR 20885 - National Park Week, 2010

    Science.gov (United States)

    2010-04-21

    ... hope at the Statue of Liberty to the harrowing Battle of Gettysburg and the quest for freedom on the... Part II The President Proclamation 8498--National Park Week, 2010 Proclamation 8499--National... / Presidential Documents#0;#0; #0; #0;Title 3-- #0;The President [[Page 20887

  11. Impact of the 20-week scan

    NARCIS (Netherlands)

    Fleurke-Rozema, Hanneke

    2017-01-01

    This thesis presents the results of a number of studies on the efficacy of the 20-week scan in detecting severe congenital anomalies. Data from two of the eight regional centers for prenatal screening was used, located in the Academic Medical Center in Amsterdam and the Academic Medical Center in

  12. Twice-weekly administration of kisspeptin-54 for 8 weeks stimulates release of reproductive hormones in women with hypothalamic amenorrhea.

    Science.gov (United States)

    Jayasena, C N; Nijher, G M K; Abbara, A; Murphy, K G; Lim, A; Patel, D; Mehta, A; Todd, C; Donaldson, M; Trew, G H; Ghatei, M A; Bloom, S R; Dhillo, W S

    2010-12-01

    Kisspeptin is a novel therapeutic target for infertility. A single kisspeptin-54 (KP-54) injection acutely stimulates the release of reproductive hormones in women with hypothalamic amenorrhea (HA), a commonly occurring condition characterized by absence of menstruation; however, twice-daily administration of KP-54 results in tachyphylaxis. We determined the time course of desensitization to twice-daily KP-54 injections, compared the effects of twice-daily and twice-weekly administration regimens of KP-54, and studied the effects of long-term twice-weekly administration of KP-54 on the release of reproductive hormones in women with HA. When KP-54 was administered twice daily, responsiveness to luteinizing hormone (LH) diminished gradually, whereas responsiveness to follicle-stimulating hormone (FSH) was nearly abolished by day 2. Twice-weekly KP-54 administration resulted in only partial desensitization, in contrast to the complete tolerance achieved with twice-daily administration. Women with HA who were treated with twice-weekly KP-54 injections had significantly elevated levels of reproductive hormones after 8 weeks as compared with treatment with saline. No adverse effects were observed. This study provides novel pharmacological data on the effects of KP-54 on the release of reproductive hormones in women with HA.

  13. Meeting the challenge of new fatherhood during the early weeks.

    Science.gov (United States)

    St John, Winsome; Cameron, Catherine; McVeigh, Carol

    2005-01-01

    To explore new/subsequent Australian fathers' perspectives on the experiences, processes, and life changes in the early weeks of fatherhood. Interpretive study using in-depth interviews and grounded theory analysis techniques, based on a symbolic interactionist framework. Participants were recruited from the postnatal wards of a major public hospital, early discharge program, and early childhood centers in southeast Queensland, Australia. Eighteen first-time/subsequent fathers interviewed 6 to 12 weeks after the birth. Although rewarding, fathers found new or expanding fatherhood to be a significant challenge and time of change. Major themes included making a commitment, taking responsibility, negotiating responsibilities, developing and maintaining relationships, maintaining family integrity, balancing activities, and perceiving the self as father. Work had a major impact on fathers' ability to participate with their family and newborn. To manage, fathers sought to balance the demands of work and home, deal with stressors, manage their time, develop routines, and reprioritize. Fathers developed a sense of themselves as fathers over time, building confidence and deriving satisfaction from their fathering role. A range of competing factors affected fathers' ability to participate in the home with their newborn in the early weeks after birth.

  14. Intracorneal blood removal six weeks after canaloplasty

    Directory of Open Access Journals (Sweden)

    Alberto Rossetti

    2013-01-01

    Full Text Available In a 71-year-old patient with bilateral open-angle glaucoma, intracorneal blood was found after a canaloplasty procedure in the right eye. Six weeks after surgery on ultrasound biomicroscopy examination, liquified blood and blood clots could be observed nasally in the deep corneal stroma close to the Descemet′s membrane. The intracorneal blood was washed out with balanced saline solution following deep corneal incision and lamellar dissection. Descemet′s membrane was reattached with air injection into the anterior chamber. Two months later, visual acuity improved to 20/50, intraocular pressure was 16 mm Hg without medication and confocal microscopy showed deep stromal folds and limited endothelial cell loss. Viscoelastic entering the cornea at Schwalbe′s line and reflux of blood from the collector channels to Schlemm′s canal can account for corneal hematoma. Even six weeks after canaloplasty, successful blood removal could be fulfilled without rupturing the Descemet′s membrane.

  15. Citizen weeks or the psychologizing of citizenship.

    Science.gov (United States)

    Loredo-Narciandi, José Carlos; Castro-Tejerina, Jorge

    2013-02-01

    Arland Deyett Weeks (1871-1936) was an American educator and social reformer who published The Psychology of Citizenship in 1917 with the intention of compiling the psychological, psychobiological, and psychosocial knowledge needed for governing modern democratic Western industrialized societies, as well as offering suggestions for intervention and social reform in the educational, legal, and occupational domains. His point of view can be placed within the progressive social and intellectual movement that characterized the policies of the United States in the first decade of the 20th century. His sociopolitical ideas were fed by transcendental and pragmatic sources, especially with respect to the way of dealing with tension between the individual and the collective. Modern psychological techniques (occupational, educational, legal psychology, etc.) nourished his reform program. In this article, we contextualize Weeks's book within these ideas and show its historical significance in the sociocultural and intellectual context that gave it meaning.

  16. Vehicle Technologies’ Fact of the Week 2013

    Energy Technology Data Exchange (ETDEWEB)

    Davis, Stacy Cagle [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Diegel, Susan W. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Moore, Sheila A. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Boundy, Robert Gary [Roltek, Inc., Clinton, TN (United States)

    2014-04-01

    Each week the U.S. Department of Energy’s Vehicle Technology Office (VTO) posts a Fact of the Week on their website: http://www1.eere.energy.gov/vehiclesandfuels/ . These Facts provide statistical information, usually in the form of charts and tables, on vehicle sales, fuel economy, gasoline prices, and other transportation-related trends. Each Fact is a stand-alone page that includes a graph, text explaining the significance of the data, the supporting information on which the graph was based, and the source of the data. A link to the current week’s Fact is available on the VTO homepage, but older Facts are archived and still available at: http://www1.eere.energy.gov/vehiclesandfuels/facts/. This report is a compilation of the Facts that were posted during calendar year 2013. The Facts were written and prepared by staff in Oak Ridge National Laboratory's Center for Transportation Analysis.

  17. A busy week for Arts@CERN

    CERN Multimedia

    Antonella Del Rosso

    2015-01-01

    Last week, Semiconductor – the winners of the Collide@CERN Ars Electronica award for 2015 – and artists Francesco Mariotti and José­-Carlos Mariátegui visited CERN and met the scientists.   Ruth Jarman (left) and Joe Gerhardt (right) of Semiconductor with Peter Jenni, one of the scientists they met during their visit to ATLAS.   Just a few weeks ago, Ruth Jarman and Joe Gerhardt, two English artists collaborating under the name Semiconductor, were awarded the Collide@CERN Ars Electronica prize for 2015. Last week, they came on their first visit to CERN to meet the scientists and select their scientific partner in preparation for their residency. They will soon begin a two-month residency at CERN before going to Linz (Austria), where they will spend a month at the Ars Electronica Futurelab. During their residency, the artists aim to create a digital artwork elaborating on the n...

  18. Weekly cycle of minor air gases in Moscow

    Science.gov (United States)

    Lokoshchenko, Mikhail A.; Elansky, Nikolay F.; Trifanova, Alexandra V.

    2017-04-01

    The weekly cycle of the surface concentrations of five trace atmospheric gases in Moscow has been analyzed based on continuous automatic once-a-minute measurements. The data of joint ecological station of the Institute of Atmospheric Physics and Moscow State University for nine years (2002-2010) were used. This station operated in conditions of comparatively clear park zone of the University on the South-Western periphery of the city at a distance of 8 km from the city centre. Fortunately, none of the great sources of the air pollution - neither point sources, nor linear ones - are present in the vicinity of the station so that the measurements there are quite representative. Results of spectral analysis demonstrate statistically significant maximum of spectral density close to 7 days. Any clear periodicity of around seven days may be a consequence of either natural synoptic period or weekly cycle. The fact that the influence of human activity on urban air composition changes with a weekly periodicity is confirmed by statistically significant difference between concentrations of trace gases on working days and on Sunday (when emissions from both the traffic and the industrial sources are minimal). On average, both primary pollutants (nitrogen oxide and carbon oxide) and the secondary ones (NO2) show the lowest concentrations of the week on Sunday whereas ozone, by contrast, peaks on this day. Besides, usual diurnal cycle of air pollutants is transformed on Sunday - e.g., secondary nocturnal maximum of ozone in the city is absent on Sunday like at rural area. On Saturday concentrations of trace gases are in between working days and Sunday; this 'Saturday effect' is a result of a gradual clearing of the urban air. An additional effect is that in the first half of Monday (before noon) surface concentrations of NO and NO2 are generally less, whereas the concentration of O3 is, on the contrary, a bit higher than at the same time on the rest of working days. The 'Monday

  19. Weekly Cycles in Daily Report Data: An Overlooked Issue.

    Science.gov (United States)

    Liu, Yu; West, Stephen G

    2016-10-01

    Daily diaries and other everyday experience methods are increasingly used to study relationships between two time-varying variables X and Y. Although daily data potentially often have weekly cyclical patterns (e.g., stress may be higher on weekdays and lower on weekends), the majority of daily diary studies have ignored this possibility. In this study, we investigated the effect of ignoring existing weekly cycles. We reanalyzed an empirical dataset (stress and alcohol consumption) and performed Monte Carlo simulations to investigate the impact of omitting weekly cycles. In the empirical dataset, ignoring cycles led to the inference of a significant within-person X-Y relation whereas modeling cycles suggested that this relationship did not exist. Simulation results indicated that ignoring cycles that existed in both X and Y led to bias in the estimated within-person X-Y relationship. The amount and direction of bias depended on the magnitude of the cycles, magnitude of the true within-person X-Y relation, and synchronization of the cycles. We encourage researchers conducting daily diary studies to address potential weekly cycles in their data. We provide guidelines for detecting and modeling cycles to remove their influence and discuss challenges of causal inference in daily experience studies. © 2015 Wiley Periodicals, Inc.

  20. Future Circular Collider study week 2017

    CERN Document Server

    2017-01-01

    The annual meetings of the worldwide Future Circular Collider study (FCC) are major international events that review the progress in every domain which is relevant to develop feasible concepts for a next generation frontier particle accelerate based high-energy physics research infrastructure. This 3rd meeting is jointly organised by CERN and DESY. It is also the annual meeting of the EuroCirCol EC Horizon 2020 Research and Innovation Action project. Previous events took place in Washington and Rome. In 2017 the FCC Week will take place in Berlin, Germany between May 29 and June 2.

  1. Can a text message a week improve breastfeeding?

    Science.gov (United States)

    Gallegos, Danielle; Russell-Bennett, Rebekah; Previte, Josephine; Parkinson, Joy

    2014-11-06

    Breastfeeding is recognised as the optimal method for feeding infants with health gains made by reducing infectious diseases in infancy; and chronic diseases, including obesity, in childhood, adolescence and adulthood. Despite this, exclusivity and duration in developed countries remains resistant to improvement. The objectives of this research were to test if an automated mobile phone text messaging intervention, delivering one text message a week, could increase "any" breastfeeding rates and improve breastfeeding self-efficacy and coping. Women were eligible to participate if they were: over eighteen years; had an infant less than three months old; were currently breastfeeding; no diagnosed mental illness; and used a mobile phone. Women in the intervention group received MumBubConnect, a text messaging service with automated responses delivered once a week for 8 weeks. Women in the comparison group received their usual care and were sampled two years after the intervention group. Data collection included online surveys at two time points, week zero and week nine, to measure breastfeeding exclusivity and duration, coping, emotions, accountability and self-efficacy. A range of statistical analyses were used to test for differences between groups. Hierarchical regression was used to investigate change in breastfeeding outcome, between groups, adjusting for co-variates. The intervention group had 120 participants at commencement and 114 at completion, the comparison group had 114 participants at commencement and 86 at completion. MumBubConnect had a positive impact on the primary outcome of breastfeeding behaviors with women receiving the intervention more likely to continue exclusive breastfeeding; with a 6% decrease in exclusive breastfeeding in the intervention group, compared to a 14% decrease in the comparison group (p issues. Australian New Zealand Clinical Trials Registry: ACTRN12614001091695.

  2. PLACENTAL INSUFFICIENCY IN PREGNANCY AFTER 40th WEEK OF GESTATION

    Directory of Open Access Journals (Sweden)

    Vladimir Antic

    2007-12-01

    Full Text Available Pregnancy after the 40th week of gestation is often a great dilemma for obstetrician in diagnostic, therapeutic and in psychological terms as well. The aim of this study was to confirm the phenomenon of placental insufficiency in pregnancy after the 40th gestation week, the modality of delivery and perinatal outcome.The study comprised 3405 deliveries in a period of one year, 391 of which were terminated after the end of the 40th gestation week, including healthy pregnant women with singleton pregnancies. Control group included healthy pregnant women delivered between the 37th and 40th gestation week.The incidence of deliveries after the 40th week of gestation is 11.48%. Non-stress test was reactive in 99.65% of women in the study group. At the same time, CST (constriction– stress test was assessed as negative in 78.67% of cases. The pathological CST was found in only 1.33% of cases. Doppler ultrasound measurements showed the increased resistance in umbilical artery flow in 3% of cases. Vacuum extraction was used for 16.62%of deliveries in the study group, and 8.73% of deliveries in the control group (χ2=23.24;p<0.001. In the study group, Caesarean section was performed in 14.58% of cases, and in control group in 9.07% (χ2=11.09; p<0.001.Placental insufficiency induced by duration of pregnancy is a rear phenomenon in uncompromised pregnancy. There was no significant difference in the morbidity and mortality rates between the study and control group.

  3. Does Shortening the School Week Impact Student Performance? Evidence from the Four-Day School Week

    OpenAIRE

    D. Mark Anderson; Mary Beth Walker

    2015-01-01

    School districts use a variety of policies to close budget gaps and stave off teacher layoffs and furloughs. More schools are implementing four-day school weeks to reduce overhead and transportation costs. The four-day week requires substantial schedule changes as schools must increase the length of their school day to meet minimum instructional hour requirements. Although some schools have indicated this policy eases financial pressures, it is unknown whether there is an impact on student ou...

  4. Medical image of the week: bronchogenic cysts

    Directory of Open Access Journals (Sweden)

    Sears SP

    2018-03-01

    Full Text Available Bronchogenic cysts are congenital foregut malformations forming from abnormal budding of the bronchial tree between the 4th and 6th weeks of embryonic development. While identified primarily in children, the cysts are often asymptomatic and may not be identified until adulthood. Most (70% are within the middle mediastinum and contain fluid or proteinaceous material. When involving the parenchyma, they generally do not communicate with the tracheobronchial tree. Communication with the airways may develop following infection, procedures, or trauma and may result in lesions with an air-fluid level (Figures 1 and 2. Bronchogenic cysts may be complicated by infection, bleeding, fistula formation, or most concerning, by malignant transformation. Unless the cyst contains air, it may manifest as a solitary pulmonary nodule on plain radiographs. Computed tomography or T2-weighted MRI images are used to confirm the diagnosis.

  5. Chernobyl: Chronicle of difficult weeks [videorecording

    Energy Technology Data Exchange (ETDEWEB)

    Volodymyr, S

    1987-07-01

    1. Chernobyl : chronicle of difficult weeks. Shevchenko's film crew was the first in the disaster zone following the meltdown of the core of the Chernobyl nuclear power plant in 1986. They shot continuously for more than three months. Portions of the film are exposed with white blotches - a radiation leakage. The film demonstrates how authorities and volunteers dealt with the accident, shows the efforts to get the fire under control, to take care of patients with radiation injuries, and to evacuate about 100,000 inhabitants of the area. 2. The BAM zone : permanent residents. The Baikal-Amur Mainline (BAM) railroad in Siberia is called the longest monument to the stagnation of the Brezhnev years. The film shows the lives and fates of the people in contrast to the marches and songs praising the project.

  6. The impact of alternate weekly collections on waste arisings

    Energy Technology Data Exchange (ETDEWEB)

    Williams, I.D., E-mail: idw@soton.ac.uk [Waste Management Research Group, Faculty of Engineering and the Environment, Lanchester Building, University of Southampton, University Rd, Highfield, SOUTHAMPTON, Hampshire, SO17 1BJ (United Kingdom); Cole, C. [Centre for Innovative and Collaborative Construction Engineering, School of Civil and Building Engineering, Loughborough University, Epinal Way, Loughborough, LE11 3TU (United Kingdom)

    2013-02-15

    Residual waste is commonly collected separately from recyclable and organic materials. Different forms of collection and disposal are used internationally since regional or municipal authorities have to adapt to their own circumstances. Many authorities have adopted an alternate weekly collection (AWC) of residual waste and recyclables to force/encourage householders to recycle; however, the degree to which they achieve waste reduction has yet to be reliably quantified. This study reports on how the introduction of AWCs affects household waste arisings. The paper evaluates single and dual stream collection methods and compares their performance with the previous system. Household waste collection trials were conducted between March and June 2009 in England (Lichfield). The trials examined changes to frequency of collection, type of container issued, amounts of sorting required of residents, household participation and productivity levels. A survey of households was completed before any changes were implemented. The quantity of recyclates collected was examined for 2008/2009 and 2009/2010. The study showed that the AWC scheme positively impacted on recycling rates and household behaviour, with no adverse impacts on public participation, household waste arisings or the local environment. No public health problems were reported. Both trials saw an increase in the quantities of recyclates collected per household during the trial period compared to the same period of time in the previous year. The dual stream performed better than the single stream, collecting an average of 5.94 kg/hh/week compared to an average of 5.63 kg/hh/week. The single stream system showed a greater increase in the weight of material collected (0.53 kg/hh/week vs. 0.48 kg/hh/week). Participation and set-out rates showed an increase during the trial period. The single stream option (comingled materials in one container) outperformed the dual stream service. The reduction in costs and improved

  7. The impact of alternate weekly collections on waste arisings

    International Nuclear Information System (INIS)

    Williams, I.D.; Cole, C.

    2013-01-01

    Residual waste is commonly collected separately from recyclable and organic materials. Different forms of collection and disposal are used internationally since regional or municipal authorities have to adapt to their own circumstances. Many authorities have adopted an alternate weekly collection (AWC) of residual waste and recyclables to force/encourage householders to recycle; however, the degree to which they achieve waste reduction has yet to be reliably quantified. This study reports on how the introduction of AWCs affects household waste arisings. The paper evaluates single and dual stream collection methods and compares their performance with the previous system. Household waste collection trials were conducted between March and June 2009 in England (Lichfield). The trials examined changes to frequency of collection, type of container issued, amounts of sorting required of residents, household participation and productivity levels. A survey of households was completed before any changes were implemented. The quantity of recyclates collected was examined for 2008/2009 and 2009/2010. The study showed that the AWC scheme positively impacted on recycling rates and household behaviour, with no adverse impacts on public participation, household waste arisings or the local environment. No public health problems were reported. Both trials saw an increase in the quantities of recyclates collected per household during the trial period compared to the same period of time in the previous year. The dual stream performed better than the single stream, collecting an average of 5.94 kg/hh/week compared to an average of 5.63 kg/hh/week. The single stream system showed a greater increase in the weight of material collected (0.53 kg/hh/week vs. 0.48 kg/hh/week). Participation and set-out rates showed an increase during the trial period. The single stream option (comingled materials in one container) outperformed the dual stream service. The reduction in costs and improved

  8. Winter fuels report, week ending October 5, 1990

    Energy Technology Data Exchange (ETDEWEB)

    1990-10-11

    The Winter Fuels Report is intended to provide concise, timely information to the industry, the press, policymakers, consumers, analysts, and state and local governments on the following topics: distillate fuel oil net production, imports and stocks for all PADD's and product supplied on a US level; propane net production, imports and stocks for Petroleum Administration for Defense Districts (PADD) I, II, and III; natural gas supply and disposition and underground storage, for the United States and consumption for all PADD's; residential and wholesale pricing data for propane and heating oil for those states participating in the joint Energy Information Administration (EIA)/State Heating Oil and Propane Program; crude oil and petroleum price comparisons for the United States and selected cities; and US total heating degree-days by city. This report will be published weekly by the EIA starting the first week in October 1990 and will continue until the first week in April 1991. The data will also be electronically after 5:00 p.m. on Thursday during the heating season through the EIA Electronic Publication System (EPUB). See page ii for details. 12 tabs.

  9. Special Relativity in Week One: 3) Introducing the Lorentz Contraction

    Science.gov (United States)

    Huggins, Elisha

    2011-05-01

    This is the third of four articles on teaching special relativity in the first week of an introductory physics course.1,2 With Einstein's second postulate that the speed of light is the same to all observers, we could use the light pulse clock to introduce time dilation. But we had difficulty introducing the Lorentz contraction until we saw the movie "Time Dilation, an Experiment with Mu-Mesons" by David Frisch and James Smith.3,4 The movie demonstrates that time dilation and the Lorentz contraction are essentially two sides of the same coin. Here we take the muon's point of view for a more intuitive understanding of the Lorentz contraction, and use the results of the movie to provide an insight into the way we interpret experimental results involving special relativity.

  10. Medical image of the week: aspergilloma

    Directory of Open Access Journals (Sweden)

    Hsu W

    2014-05-01

    Full Text Available No abstract available. Article truncated after 150 words. A 69-year-old woman, a current smoker, with very severe chronic obstructive pulmonary disease and prior atypical mycobacterium, was found unresponsive by her family and intubated in the field by emergency medical services for respiratory distress. Her CT thorax showed severe emphysematous disease, apical bullous disease, and a large left upper lobe cavitation with debris (Figure 1. She was treated with broad-spectrum antibiotics and anti-fungal medications. Hemoptysis was never seen. Sputum cultures over a span of two weeks repeatedly showed Aspergillus fumigatus and outside medical records confirmed the patient had a known history of stable aspergilloma not requiring therapy. Aspergillomas usually arises in cavitary areas of the lung damaged by previous infections. The fungus ball is a combination of colonization by Aspergillus hyphae and cellular debris. Individuals with aspergillomas are usually asymptomatic or have mild symptoms (chronic cough and do not require treatment unless it begins to invade into the cavity ...

  11. The new Bulletin arrives in two weeks

    CERN Multimedia

    2006-01-01

    In May, you will discover a redesigned CERN Bulletin. Starting with the first May issue (No. 19-20/2006), the format of the CERN Bulletin will change completely. The page layout will be more attractive, reminiscent of a proper newspaper, with pictograms to identify the different sections. The information provided will also be more visible. The Bulletin was much in need of a makeover as its current layout dates back to 1976! The introduction of the new format will coincide with the introduction of a new means of distribution. You will still receive the elctronic version of the Bulletin every week directly on your computer. However, in order to avoid the waste from the dozens of copies that linger unread in people's mailboxes, the paper version will be available at a series of distribution points around the Laboratory. You will find the Bulletin along with the Staff Association newsletter at the cafeteria closest to your office. The Bulletin will be available from the following distribution points: On the M...

  12. Medical image of the week: headcheese sign

    Directory of Open Access Journals (Sweden)

    Adial A

    2018-04-01

    Full Text Available No abstract available. Article truncated at 150 words. A 95-year-old woman with a past medical history of breast cancer and mastectomy presented with fevers, cough productive of sputum and progressive dyspnea for 2 weeks. She denies any recent travel or sick contacts but has bird at home since last 10 years. She was afebrile but tachypneic with respiratory rate of 25 and sPO2 of 86% on room air. Her initial chest examination reveals coarse rhonchi in both lungs. Labs were significant for a sodium of 118 mEq/L, leukocytosis to 18,000 cells/mcL without peripheral eosinophilia. Arterial blood gas showed pO2 of 55 mm Hg, pCO2 of 48 mm Hg and pH of 7.44. An initial chest X-ray was positive for extensive bilateral pulmonary infiltrates predominantly in the mid and lower lungs with areas of airspace consolidation. Her urine Streptococcus pneumoniae antigen was negative as well as rapid influenza and a respiratory syncytial virus panel. The high resolution thoracic CT …

  13. Predictors of hangover during a week of heavy drinking on a holiday

    DEFF Research Database (Denmark)

    Hesse, Morten; Tutenges, Sébastien

    2010-01-01

    units in the whole sample. The severity of hangover increased significantly during a week of heavy drinking and there was a time * number of drinks interaction, indicating that the impact of alcohol consumed on hangover became more pronounced later in the week. Levels of drinking before the holiday did...

  14. Weekly enrollment and usage patterns in an Internet smoking cessation intervention

    Directory of Open Access Journals (Sweden)

    Kevin Welding

    2017-09-01

    Conclusions: Consistent with prior research, the beginning of the week appears to be a time when individuals are more likely to enroll in an Internet smoking cessation intervention and engage with its core features. Emphasizing marketing and promotional efforts during the beginning of the week could result in greater reach of Internet smoking cessation interventions.

  15. Eight-Week Traditional Mat Pilates Training-Program Effects on Adult Fitness Characteristics

    Science.gov (United States)

    Rogers, Kate; Gibson, Ann L.

    2009-01-01

    We investigated responses of adult, novice practitioners (n = 9) to an 8-week traditional mat Pilates program (P) that met 1 hr/day three times/week. Classes consisted primarily of beginner and intermediate level exercises. Compared to an active control group (C; n = 13) that showed no improvements, those in P significantly (p less than 0.05)…

  16. Physical and psychological benefits of once-a-week Pilates exercises in young sedentary women: A 10-week longitudinal study.

    Science.gov (United States)

    Tolnai, Nóra; Szabó, Zsófia; Köteles, Ferenc; Szabo, Attila

    2016-09-01

    Pilates exercises have several demonstrated physical and psychological benefits. To date, most research in this context was conducted with symptomatic or elderly people with few dependent measures. The current study examined the chronic or longitudinal effects of very low frequency, once a week, Pilates training on several physical and psychological measures, over a 10-week intervention, in young, healthy, and sedentary women. Further, the study gauged the acute effects of Pilates exercises on positive- and negative affect in 10 exercise sessions. Compared to a control group, the Pilates group exhibited significant improvements in skeletal muscle mass, flexibility, balance, core- and abdominal muscle strength, body awareness, and negative affect. This group also showed favorable changes in positive (22.5% increase) and negative affect (12.2% decrease) in nine out of ten exercise sessions. This work clearly demonstrates the acute and chronic benefits of Pilates training on both physical and psychological measures. It also reveals that even only once a week Pilates training is enough to trigger detectable benefits in young sedentary women. While this frequency is below the required levels of exercise for health, it may overcome the 'lack of time' excuse for not exercising and subsequently its tangible benefits may positively influence one's engagement in more physical activity. Copyright © 2016 Elsevier Inc. All rights reserved.

  17. 77 FR 69733 - National Family Week, 2012

    Science.gov (United States)

    2012-11-21

    ... not face a choice between their jobs and meeting their families' needs. Moreover, we continue to...-being of our sons and daughters. Finally, at a time when many of our military families are stretched...

  18. Four Weeks of Mobility After 8 Weeks of Immobility Fails to Restore Normal Motion

    Science.gov (United States)

    Trudel, Guy; Zhou, Jian; Uhthoff, Hans K.

    2008-01-01

    Prolonged immobilization reduces passive range of motion of joints creating joint contractures. Whether and to what extent these iatrogenic contractures can be reduced is unknown. We raised three questions using an animal model: What degree of contracture remains at the end of a defined remobilization period? Do contractures in sham-operated and immobilized joints differ? What is the contribution of the posterior knee capsule in limiting knee extension? We immobilized one knee of 11 adult male rats in flexion to induce a joint contracture; 10 control animals underwent a sham operation. After 8 weeks, the internal fixation device was removed, and the animals were allowed to resume unrestricted activity for 4 weeks at the end of which the knee range of motion was measured with standardized torques. The mean flexion contracture was higher in the immobilized group (51.9° ± 2.8°) than in the sham-operated group (18.9° ± 2.1°). Eighty-eight percent of the contractures remained in the immobilized group after dividing skin and muscle, suggesting an important contribution of the posterior knee capsule in limiting knee mobility. Based on our preliminary study the range of motion of rat knees immobilized for 8 weeks remained substantially reduced after a 4-week period of unassisted remobilization. PMID:18299947

  19. Physical activity initiated by employer and its health effects; an eight week follow-up study

    Directory of Open Access Journals (Sweden)

    Marit Skogstad

    2016-05-01

    Full Text Available Abstract Background While the health benefits of physical activity are well established, little is known about health effects of physical activity programs initiated by employer. Methods Background data and level of physical activity were collected by questionnaire among 78 men and 43 women working in road maintenance pre and post an 8-week physical activity motivational program. As a part of the program steps measured by accelerometer were registered online where team and individual performances could be continuously monitored. The physical activity levels were registered as 1 those physical active ≤1 time per week, 2 2–3 times per week and 3 ≥4 times a week. Maximal oxygen uptake (VO2max, blood pressure, resting heart rate (RHR and blood samples (glycosylated hemoglobin, lipids and C-reactive protein were obtained at baseline and after eight weeks. Mixed models were applied to evaluate associations between physical activity and health parameters. Results With ≤1 time per week as reference, exercising 2–3 times per week at baseline was associated with higher levels of VO2max. During follow-up, VO2max increased with 2.8 mL ∙ kg−1∙ min−1 (95 % CI = 1.4, 4.3. Women had more favorable body mass index (BMI, blood pressure, RHR and lipid profile than men. Total cholesterol, low density lipoprotein (LDL, RHR and diastolic blood pressure (dBP were lower among participants who exercised 2–3 times per week or ≥4 times a week, compared with those with ≤1 time per week. Half of the participants reported increased daily PA during follow-up, with high intensity PA such as jogging by 8.6 min (SD 14.6 and 8.3 min (SD 18.2, among women and men, respectively. During follow-up dBP increased among men. Further, total cholesterol and LDL were reduced by 0.12 mmol/L and 0.13 mmol/L, respectively (95 % CI = −022, –0.01 and −0.22,–0.04. Conclusions Exercise several times a week was associated with lower blood pressure and a

  20. Weekly patterns, diet quality and energy balance.

    Science.gov (United States)

    McCarthy, Sinéad

    2014-07-01

    Human behaviour is made up of many repeated patterns and habitual behaviours. Our day to day lives are punctuated by work, education, domestic chores, sleep and food. Changes in daily patterns such as not working in paid employment or attending school on the weekend contribute significantly to changes in dietary patterns of food consumption, patterns of physical activity and ultimately energy balance. The aim of this paper is to adopt a life-course perspective and explore the changes in dietary quality and physical activity patterns across the week from young children to elderly adults with a focus on Western cultures. Research literature indicates that the dietary quality is somewhat poorer on the weekends, characterised by higher fat intakes, higher alcohol intakes and consequently higher energy intakes. This increase in energy intake is not necessarily offset by an increase in activity, rather an increase in sedentary behaviours. Some research has observed an increase of more than 100 cal per day over the weekend in American adults. Over the course of one year, this can result in a significant increase in body mass. Some of the interventions in tackling obesity and diet related behaviours must focus on the changes in the weekend behaviour of consumers in terms of both food and activity. These efforts should also focus on increasing consumer awareness of the long term consequences of the short lived weekend excess as well as putting in place practical measures and interventions that are evidence based and targeted to consumer needs. Copyright © 2014 Elsevier Inc. All rights reserved.

  1. Night work, long work weeks, and risk of accidental injuries. A register-based study

    DEFF Research Database (Denmark)

    Larsen, Ann D; Hannerz, Harald; Møller, Simone V

    2017-01-01

    of the European Labour Force Survey from 1999-2013. The current study was based on 150 438 participants (53% men and 47% women). Data on accidental injuries were obtained at individual level from national health registers. We included all 20-59-year-old employees working ≥32 hours a week at the time...... of the interview. We used Poisson regression to estimate the relative rates (RR) of accidental injuries as a function of night work or long work weeks (>40 hours per week) adjusted for year of interview, sex, age, socioeconomic status (SES), industry, and weekly working hours or night work. Age, sex and SES were....... No associations were found between long work weeks (>40 hours) and accidental injuries. Conclusion: We found a modest increased risk of accidental injuries when reporting night work. No associations between long work weeks and risk of accidental injuries were observed. Age, sex and SES showed no trends when...

  2. Winter fuels report. Week ending, January 26, 1996

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-01-23

    The Winter Fuels Report is intended to provide concise, timely information to the industry, the press, policymakers, consumers analysts, and State and local governments on the following topics: (1) distillate fuel oil net production, imports and stocks on a U.S. level and for all Petroleum Administration for Defense Districts (PADD) and product supplied on a U.S. level; (2) propane net production, imports and stocks on a U.S. level and for PADD`s I, II, and III; (3) natural gas supply and disposition and underground storage for the U.S. and consumption for all PADD`s; as well as selected National average prices; (4) residential and wholesale pricing data for heating oil and propane for those States participating in the joint Energy Information Administration (EIA)/State Heating Oil and Propane Program; (5) crude oil and petroleum price comparisons for the U.S. and selected cities; and (6) a 6-10 Day and 30-Day outlook for temperature and precipitation and U.S. total heating degree-days by city. The distillate fuel oil and propane supply data are collected and published weekly. The data are based on company submissions for the week ending 7:00 a.m. for the preceding Friday. Weekly data for distillate fuel oil are also published in the Weekly Petroleum Status Report. Monthly data for distillate fuel oil and propane are published in the Petroleum Supply Monthly. The residential pricing information is collected by the EIA and the State Energy Offices on a semimonthly basis for the EIA/State Heating Oil and Propane Program. The wholesale price comparison data are collected daily and are published weekly. Residential heating fuel prices are derived from price quotes for home delivery of No. 2 fuel oil and propane. As such, they reflect prices in effect on the dates shown. Wholesale heating oil and propane prices are estimates using a sample of terminal quotes to represent average State prices on the dates given.

  3. 75 FR 70999 - National Entrepreneurship Week, 2010

    Science.gov (United States)

    2010-11-19

    ... the prevalence and success of new start-ups. Business leaders can mentor a budding entrepreneur who... decisive action to accelerate growth and remove barriers for entrepreneurs and small business owners to grow, hire, and prosper. At a time when small business lending standards had tightened considerably...

  4. 76 FR 29139 - World Trade Week, 2011

    Science.gov (United States)

    2011-05-19

    ... embody the ingenuity and entrepreneurship that has defined our Nation since its founding, and they consistently reinvent themselves to adapt to changing times. As we recover from a historic economic recession... growth. Last year, my Administration launched the National Export Initiative, an effort to marshal the...

  5. Intracranial Hemorrhage Following a 3-week Headache

    Directory of Open Access Journals (Sweden)

    John Jiao

    2017-01-01

    Full Text Available History of present illness: A 35-year-old female presented to the ED with a Glasgow Coma Scale (GCS of 11. Per her boyfriend, the patient was having headaches for the past 3 weeks. She was initially taken to an outside hospital where her GCS was reported as 13. A non-contrast head computed tomography (CT revealed a large lobar intraparenchymal hemorrhage within the left frontal parietal lobe with midline shift. Upon examination, vitals were notable for blood pressure of 209/88mmHg, and her left pupil was fixed and dilated. The patient had extension of her right arm to noxious stimuli, paralysis of her right leg, and purposeful movement of the left arm and left leg. The patient was started on a nicardipine drip in the ED and subsequently taken to the operating room for a decompressive craniectomy. Significant findings: The patient’s head CT showed a significant area of hyperdensity consistent with an intracranial hemorrhage located within the left frontal parietal lobe (red arrow. Additionally, there is rightward midline shift up to 1.1cm (green arrow and entrapment of the right lateral ventricle (blue arrow. Discussion: Intraparenchymal hemorrhage (IPH is associated with high morbidity and mortality. Although the mortality for subarachnoid hemorrhage (SAH has declined steadily over the past several decades, the mortality for IPH mortality has not significantly.1 One of the most serious considerations when treating a patient with IPH is the management of intracranial pressure (ICP.2 Once an IPH is identified, immediate steps should be taken to bring ICP within acceptable levels including elevating the head of the bed to 30 degrees, sedation, and controlling hypertension with medications.2-3 Even with early and aggressive care, the prognosis for IPH remains poor; the 30-day mortality rate for IPH is estimated to be less than 50%, and a 2010 systematic review estimated only 12-39% of IPH patients achieve independent function.4-5 Predictors of

  6. Dichorionic twin ultrasound surveillance: sonography every 4 weeks significantly underperforms sonography every 2 weeks: results of the Prospective Multicenter ESPRiT Study.

    Science.gov (United States)

    Corcoran, Siobhan; Breathnach, Fionnuala; Burke, Gerard; McAuliffe, Fionnuala; Geary, Michael; Daly, Sean; Higgins, John; Hunter, Alyson; Morrison, John J; Higgins, Shane; Mahony, Rhona; Dicker, Patrick; Tully, Elizabeth; Malone, Fergal D

    2015-10-01

    A 2-week ultrasound scanning schedule for monochorionic twins is endorsed widely. There is a lack of robust data to inform a schedule for the surveillance of dichorionic gestations. We aimed to determine how ultrasound scanning that is performed at 2- or 4-week intervals (or every 4 weeks before 32 weeks' gestation and every 2 weeks thereafter) may impact the prenatal detection of fetal growth restriction (FGR) and ultimately influence timing of delivery. In a consecutive cohort of 789 dichorionic twin pregnancies that were recruited prospectively for the multicenter Evaluation of Sonographic Predictors of Restricted Growth in Twins study, ultrasound determination of fetal growth and interrogation of umbilical and middle cerebral artery Doppler scans were performed every 2 weeks from 24 weeks' gestation until delivery. Complete delivery and perinatal outcome data were recorded for all pregnancies. Where delivery was prompted by FGR, abnormal umbilical artery Doppler examination or poor biophysical profile and in the absence of ruptured membranes, onset of labor, preeclampsia, or antepartum hemorrhage, the delivery was considered "ultrasound-indicated." For ultrasound-indicated deliveries, detection probabilities for FGR/abnormal umbilical artery Doppler scans/poor biophysical were determined according to the interval between examinations, by the suppression if alternate examination data. Among 789 dichorionic twin pregnancies, 66 pairs (8%) had an "ultrasound indicated" delivery. Detection of FGR was reduced from 88-69%, and detection of abnormal umbilical artery Doppler was reduced from 82-62% when a 4-week ultrasound schedule was simulated. Both of these reductions reached statistical significance. There was a nonsignificant trend toward a reduction in the recording of oligohydramnios with a 4-week interval between examinations. This study suggests that the ultrasound surveillance program of every 2 weeks that is recommended currently for monochorionic twins

  7. Dose Estimation from Daily and Weekly Dosimetry Data

    Energy Technology Data Exchange (ETDEWEB)

    Ostrouchov, G.

    2001-11-16

    Statistical analyses of data from epidemiologic studies of workers exposed to radiation have been based on recorded annual radiation doses (yearly dose of record). It is usually assumed that the dose values are known exactly, although it is generally recognized that the data contain uncertainty due to measurement error and bias. In our previous work with weekly data, a probability distribution was used to describe an individual's dose during a specific period of time and statistical methods were developed for estimating it from weekly film dosimetry data. This study showed that the yearly dose of record systematically underestimates doses for Oak Ridge National Laboratory (ORNL) workers. This could result in biased estimates of dose-response coefficients and their standard errors. The results of this evaluation raise serious questions about the suitability of the yearly dose of record for direct use in low-dose studies of nuclear industry workers. Here, we extend our previous work to use full information in Pocket meter data and develop the Data Synthesis for Individual Dose Estimation (DSIDE) methodology. Although the DSIDE methodology in this study is developed in the context of daily and weekly data to produce a cumulative yearly dose estimate, in principle it is completely general and can be extended to other time period and measurement combinations. The new methodology takes into account the ''measurement error'' that is produced by the film and pocket-meter dosimetry systems, the biases introduced by policies that lead to recording left-censored doses as zeros, and other measurement and recording practices. The DSIDE method is applied to a sample of dose histories obtained from hard copy dosimetry records at ORNL for the years 1945 to 1955. First, the rigorous addition of daily pocket-meter information shows that the negative bias is generally more severe than was reported in our work based on weekly film data only, however, the

  8. Dose Estimation from Daily and Weekly Dosimetry Data

    International Nuclear Information System (INIS)

    Ostrouchov, G.

    2001-01-01

    Statistical analyses of data from epidemiologic studies of workers exposed to radiation have been based on recorded annual radiation doses (yearly dose of record). It is usually assumed that the dose values are known exactly, although it is generally recognized that the data contain uncertainty due to measurement error and bias. In our previous work with weekly data, a probability distribution was used to describe an individual's dose during a specific period of time and statistical methods were developed for estimating it from weekly film dosimetry data. This study showed that the yearly dose of record systematically underestimates doses for Oak Ridge National Laboratory (ORNL) workers. This could result in biased estimates of dose-response coefficients and their standard errors. The results of this evaluation raise serious questions about the suitability of the yearly dose of record for direct use in low-dose studies of nuclear industry workers. Here, we extend our previous work to use full information in Pocket meter data and develop the Data Synthesis for Individual Dose Estimation (DSIDE) methodology. Although the DSIDE methodology in this study is developed in the context of daily and weekly data to produce a cumulative yearly dose estimate, in principle it is completely general and can be extended to other time period and measurement combinations. The new methodology takes into account the ''measurement error'' that is produced by the film and pocket-meter dosimetry systems, the biases introduced by policies that lead to recording left-censored doses as zeros, and other measurement and recording practices. The DSIDE method is applied to a sample of dose histories obtained from hard copy dosimetry records at ORNL for the years 1945 to 1955. First, the rigorous addition of daily pocket-meter information shows that the negative bias is generally more severe than was reported in our work based on weekly film data only, however, the amount of bias also varies

  9. Changes in concentration of visfatin during four weeks of inpatient treatment of alcohol dependent males

    Directory of Open Access Journals (Sweden)

    Damian Czarnecki

    2015-09-01

    Conclusions: The dynamic of change in the concentration of visfatin during four weeks of abstinence is not associated with a reduction in craving for alcohol at the time and is associated with alcohol drinking and liver functioning.

  10. Designing the eatwell week: the application of eatwell plate advice to weekly food intake.

    Science.gov (United States)

    Leslie, Wilma S; Comrie, Fiona; Lean, Michael E J; Hankey, Catherine R

    2013-05-01

    To develop a menu and resource to illustrate to consumers and health professionals what a healthy balanced diet looks like over the course of a week. Development and analysis of an illustrative 7 d 'eatwell week' menu to meet current UK recommendations for nutrients with a Dietary Reference Value, with a daily energy base of 8368 kJ (2000 kcal). Foods were selected using market research data on meals and snacks commonly consumed by UK adults. Analysis used the food composition data set from year 1 (2008) of the UK National Diet and Nutrition Survey rolling programme. The eatwell week menu was developed using an iterative process of nutritional analysis with adjustments made to portion sizes and the inclusion/exclusion of foods in order to achieve the target macronutrient composition. Three main meals and two snacks were presented as interchangeable within the weekdays and two weekend days to achieve adult food and nutrient recommendations. Main meals were based on potatoes, rice or pasta with fish (two meals; one oily), red meat (two meals), poultry or vegetarian accompaniments. The 5-a-day target for fruit and vegetables (range 5-6·7 portions) was achieved daily. Mean salt content was below recommended maximum levels (<6 g/d). All key macro- and micronutrient values were achieved. Affordable foods, and those widely consumed by British adults, can be incorporated within a 7 d healthy balanced menu. Future research should investigate the effect of using the eatwell week on adults' dietary habits and health-related outcomes.

  11. A week for records… and things of record

    CERN Multimedia

    2015-01-01

    This week, the LHC set an important record on the way to the start of data taking for Run 2. At around 10.30 p.m. on Wednesday, 20 May, two bunches of particles were brought into collision at 13 TeV for the first time as part of the commissioning process for the systems that protect the detectors from stray particles. This milestone triggered ripples of excitement around the Laboratory and, coming right on schedule, is a clear sign that we are on course for physics data taking to start at the beginning of June. My congratulations go to all involved.   That was not the only record set this week: there was a sporting record as well. On Thursday, nearly 800 of you ran the traditional CERN Relay Race with 129 teams competing along with nine Nordic walkers, easily breaking the previous record of 108 teams set in 2013. However, despite so many pretenders to the crown, the course record of 10 minutes and 33 seconds set by the VELOcity team in 2013 still stands. Staying with a sporting theme, the an...

  12. Prague Overview Week, September 13th-20th, 2003

    CERN Multimedia

    Smith, K

    The week already began on Saturday for a number of system and sub-system meetings, but got into full swing on the Sunday, with a marathon session on how to tackle the challenging task of commissioning the full ATLAS spectrometer. The seeds of lots of ideas have already germinated and should begin to flower soon. Simulation studies of cosmic ray fluxes (and even early experimental measurements in Pit 1) have shown useful rates for the pre-beam phase of commissioning, and single beam measurements will also offer useful opportunities, in particular for trigger timing. Commissioning is clearly a topic which will continue to grow in importance during the next few years. On Monday we were welcomed by our Czech hosts to the first "official" session of the Overview Week, held in the Department of Mechanical Engineering of the Czech Technical University, (CTU), the oldest Technical University in Europe. ATLAS (Prague) includes groups from the CTU, the even longer established Charles University and the Czech Acad...

  13. Medical image of the week: polysomnogram artifact

    Directory of Open Access Journals (Sweden)

    Bartell J

    2015-02-01

    Full Text Available A 54 year-old man with a past medical history of attention deficit hyperactivity disorder (ADHD, low back pain, and paroxysmal supraventricular tachycardia presented to the sleep laboratory for evaluation of sleep disordered breathing. Pertinent medications include fluoxetine, ambien, and clonazepam. His Epworth sleepiness score was 18. He had a total sleep time of 12 min. On the night of his sleep study, the patient was restless and repeatedly changed positions in bed. Figures 1 and 2 show the artifact determined to be lead displacement of O1M2 after the patient shifted in bed, inadvertently removing one of his scalp electrodes. The sine waves are 60 Hz in frequency. Once the problem was identified, the lead was quickly replaced to its proper position.

  14. Trichophyton rubrum onychomycosis in an 8-week-old infant

    Directory of Open Access Journals (Sweden)

    Vinod K Khurana

    2011-01-01

    Full Text Available An 8-week-old infant presented with 7 weeks history of nail involvement and discoloration. Lesions started over the middle fingernail of right hand at 1 week of age, spreading over to other nails within 2 weeks. Only two nails of the feet were spared. On KOH examination, fungal hyphae were seen and culture showed growth of Trichophyton rubrum. The purpose is to report the earliest case of onychomycosis having multiple nail involvement of fingers and toes (18 nails.

  15. Medical image of the week: bronchiectasis

    Directory of Open Access Journals (Sweden)

    Jaffer F

    2016-06-01

    Full Text Available No abstract available. Article truncated at 150 words. A 49-year old Native American woman with chronic hypoxic and hypercarbic respiratory failure requiring 3 liters continuous via nasal cannula and nocturnal non-invasive bi-level ventilation presented with acute shortness of breath for 5 days. She has history of recurrent respiratory infections since early childhood, however over the past five years has been treated multiple times for presumed COPD exacerbation with last such treatment one month prior to admission. Upon arrival, vitals displayed elevated blood pressure 183/96. Clinical examination demonstrated morbidly obese patient in mild somnolence and has diffuse expiratory wheezing, basal crackles with reduced air entry bilaterally. Laboratory examination showed leukocytosis (13,800 cells/uL with neutrophilic predominance, thrombocytopenia (85,000 cells/uL, and elevated bicarbonate (31 mg/dL. Arterial blood gas showed pH=7.29, pCO2 756 mm Hg, and pO2 73 mm Hg. Thoracic computed tomography (CT with contrast ruled out pulmonary embolism, however demonstrated extensive cystic bronchiectasis in left upper and lower lobes, right ...

  16. Medical image of the week: sleep bruxism

    Directory of Open Access Journals (Sweden)

    Bartell J

    2015-03-01

    Full Text Available No abstract available. Article truncated at 150 words. A 42 year-old man with a past medical history of insomnia, post-traumatic stress disorder, depression and both migraine and tension headaches was referred for an overnight sleep study. He had presented to the sleep clinic with symptoms of obstructive sleep apnea. Medications included sumatriptan, amitryptiline, sertraline, and trazodone. His sleep study showed: sleep efficiency of 58.2%, apnea-hypopnea index of 33 events per hour, and arousal index of 14.5/hr. Periodic limb movement index was 29.2/hr. The time spent in the sleep stages included N1 (3.6%, N2 (72.5%, N3 (12.9%, and REM (10.9%. Figure 1 is representative of the several brief waveforms seen on his EEG and chin EMG. Sleep bruxism (SB is a type of sleep-related movement disorder that is characterized by involuntary masticatory muscle contraction resulting in grinding and clenching of the teeth and typically associated with arousals from sleep (1,2. The American academy of sleep medicine (AASM criteria for ...

  17. Medical image of the week: eosphageal perforation

    Directory of Open Access Journals (Sweden)

    Bilal J

    2015-04-01

    Full Text Available No abstract available. Article truncated after 150 words. A 74 year old man with a past medical history of esophageal strictures status post dilatation, coronary artery disease status post CABG, and atrial fibrillation presented to hospital with complaints of severe chest pain that began after the consumption of tortilla chips one hour prior to presentation. Electrocardiogram and cardiac enzymes were not consistent with acute coronary syndrome. Chest X-ray was consistent with a widened mediastinal silhouette. Contrast esophogram was negative for extra luminal extravasation. CT scan of the chest with oral contrast demonstrated thickening of the mid-thoracic esophagus with an extra-luminal focus of gas in the mediastinum along with fluid along the inferior aspect of the esophagus (Figures 1 and 2. These findings were concerning for esophageal perforation. The patient was taken to the operating room for endoscopy which showed micro perforation in mid-esophagus. Esophageal perforation remains a highly morbid condition. Mortality rates are based predominantly on time of ...

  18. Medical image of the week: phytobezoar

    Directory of Open Access Journals (Sweden)

    Hansra A

    2016-01-01

    Full Text Available No abstract available. Article truncated after 150 words. A 10-year-old boy with a history of non-verbal autism presented to the hospital with symptoms of chronic malnourishment. He was recently started on a specific carbohydrate rich diet, as outlined by a popular mainstream nutrition book, with hopes of improvement in adverse behavior. Prior to the start of this new diet, he consistently demonstrated an increased craving for food and was described to have an insatiable appetite. Though he was relatively non-verbal at baseline, he intermittently voiced his hunger and associated abdominal pain. A supine abdominal radiograph obtained immediately after admission showed a moderate gastric distension with a significant stool burden. Follow-up radiographs of the abdomen were obtained after two days of medical attempts to clear out the gastrointestinal system. The supine frontal radiograph at this time showed a massively distended stomach with a mottled appearance and considerable mass effect on the transverse colon (Figure 1. The interpreting pediatric radiologist ...

  19. Medical image of the week: Lynch syndrome

    Directory of Open Access Journals (Sweden)

    Athale A

    2016-11-01

    Full Text Available No abstract available. Article truncated at 150 words. A 43-year-old woman with a history of anemia, thrombocytopenia, and recent treatment for pyelonephritis was transferred to our hospital for increasing shortness of breath. Four months prior to admission, she developed unprovoked bilateral deep vein thrombosis (DVT and pulmonary emboli (PE and was started on rivaroxaban at that time. At presentation, she was complaining of worsening shortness of breath, heavy menstrual bleeding and pain in her calves. CT angiography of chest showed multiple pulmonary emboli to the lower lobes and left upper lobe (Figure 1 and lower extremity venous Doppler showed extensive, acute deep vein thrombosis involving the femoral, popliteal and calf veins bilaterally. Rivaroxaban was held due to anemia and thrombocytopenia and there was concern for respiratory failure since she developed new DVT and PE. She was transfused with 1 unit of packed red blood cells and started on a heparin drip. She continued to have significant menorrhagia, the ...

  20. LIMITED RESTAURANT SERVICE: EASTER WEEK-END

    CERN Multimedia

    2004-01-01

    As Friday April 9 and Monday April 12 2004 are CERN holidays, restaurants no. 1 (Bldg. 501- Meyrin) and no. 3 (Bldg. 866 - Prévessin) will be closed and will remain closed on Saturday and Sunday, April 10 - 11. They will reopen on Tuesday, April 13 at 7 a.m. During these four days, a limited service will be provided by restaurant no. 2 (Bldg. 504 - Meyrin): on Friday and Monday from 8 a.m. to 9 p.m. and on Saturday and Sunday from 9 a.m. to 8.30 p.m. Hot meals will be served from 11.30 a.m. to 2 p.m. and from 6 p.m. to 7.30 p.m. On Thursday, April 8, all three restaurants will operate according to the usual times except for restaurant no. 1 which will close at 9 p.m. instead of 1 a.m.

  1. The 5x1 DAFNE study protocol: a cluster randomised trial comparing a standard 5 day DAFNE course delivered over 1 week against DAFNE training delivered over 1 day a week for 5 consecutive weeks

    Directory of Open Access Journals (Sweden)

    Elliott Jackie

    2012-11-01

    Full Text Available Abstract Background Structured education programmes are now established as an essential component to assist effective self-management of diabetes. In the case of Type 1 diabetes, the Dose Adjustment For Normal Eating (DAFNE programme improves both glycaemic control and quality of life. Traditionally delivered over five consecutive days, this format has been cited as a barrier to participation by some patients, such as those who work full-time. Some centres in the UK have organised structured education programmes to be delivered one day a week over several consecutive weeks. This type of format may add benefit by allowing more time in which to practice skills between sessions, but may suffer as a result of weaker peer support being generated compared to that formed over five consecutive days. Methods/design We aim to compare DAFNE delivered over five consecutive days (1 week course with DAFNE delivered one day a week over five weeks (5 week course in a randomised controlled trial. A total of 213 patients were randomised to attend either a 1 week or a 5 week course delivered in seven participating centres. Study outcomes (measured at baseline, 6 and 12 months post-course include HbA1c, weight, self-reported rates of severe hypoglycaemia, psychosocial measures of quality of life, and cost-effectiveness. Generalisability was optimised by recruiting patients from DAFNE waiting lists at each centre, and by mailing eligible patients from hospital clinic lists. The inclusion and exclusion criteria were identical to those used to recruit to a standard DAFNE course (e.g., HbA1c Discussion This trial has been designed to test the hypothesis that the benefits of delivering a structured education programme over 5 weeks are comparable to those observed after a 1 week course. The results of the trial and the qualitative sub-study will both inform the design and delivery of future DAFNE courses, and the development of structured education programmes in other

  2. Markovian Approach for the Analysis and Prediction of Weekly ...

    African Journals Online (AJOL)

    ADOWIE PERE

    reveals that, a week of high rainfall cannot be followed by another week of high rainfall , a week of high rainfall cannot be followed by a ... intensity. Arumugam and Karthik(2016) have investigated the variations of annual rainfall in. Tirunelveli district, India based on stochastic method. Rainfall data for 44 years was used, the.

  3. 75 FR 10993 - Save Your Vision Week, 2010

    Science.gov (United States)

    2010-03-10

    ... proclaim the first week in March of each year as ``Save Your Vision Week.'' NOW, THEREFORE, I, BARACK OBAMA... Your Vision Week, 2010 By the President of the United States of America A Proclamation While many... identified risk factors, early detection methods, and new treatments for many eye conditions, but individuals...

  4. Expand Your Child's Vocabulary: A Twelve-Week Plan.

    Science.gov (United States)

    Smith, Carl B.

    This booklet shows parents how to help their children develop a number of strategies for understanding words by working together on a methodical, 12-week program of word study. Sections of the booklet describe the program week by week. The techniques described are: Read and Use Context; Search for Synonyms, Antonyms, Homonyms; Learn Important…

  5. Weekly scheduling of cisplatin: feasibility, efficacy and perspective

    NARCIS (Netherlands)

    A.S.Th. Planting (André)

    1996-01-01

    textabstractIn this thesis studies of weekly administration of cisplatin are presented. Weekly administration of cisplatin is not new: already in the seventies weekly cisplatin regimens were explored but they were abandoned because of hematologic, renal and gastrointestinal toxicity. The

  6. Safety of 8-weeks oral administration of Arctium lappa L.

    Science.gov (United States)

    Bok, So-Hyeon; Cho, Seung Sik; Bae, Chun-Sik; Park, Dae-Hun; Park, Kyung-Mok

    2017-09-01

    Recently, worldwide dietary reference intakes have been considered an important guideline for public health. Some governments and the World Health Organization (WHO) provide guidelines concerning dietary intake. Although an ingredient may have a history of use as a culinary material, changes in the environment over time suggest that the acceptable maximum intake each of food/culinary material should be regularly evaluated. Arctium lappa L. has been used as a culinary material for many centuries in Korea and Japan and some recent studies have reported related therapeutic effects. However, there are no reports on the safety of repeated oral administration. In this study, we evaluated the safety of a 8-weeks repeated oral intake of A. lappa . We concluded that treatment with lappa , which was within the safety range, resulted in body weight decrease and blood glucose suppression.

  7. Cortical Reorganisation during a 30-Week Tinnitus Treatment Program.

    Directory of Open Access Journals (Sweden)

    Catherine M McMahon

    Full Text Available Subjective tinnitus is characterised by the conscious perception of a phantom sound. Previous studies have shown that individuals with chronic tinnitus have disrupted sound-evoked cortical tonotopic maps, time-shifted evoked auditory responses, and altered oscillatory cortical activity. The main objectives of this study were to: (i compare sound-evoked brain responses and cortical tonotopic maps in individuals with bilateral tinnitus and those without tinnitus; and (ii investigate whether changes in these sound-evoked responses occur with amelioration of the tinnitus percept during a 30-week tinnitus treatment program. Magnetoencephalography (MEG recordings of 12 bilateral tinnitus participants and 10 control normal-hearing subjects reporting no tinnitus were recorded at baseline, using 500 Hz, 1000 Hz, 2000 Hz, and 4000 Hz tones presented monaurally at 70 dBSPL through insert tube phones. For the tinnitus participants, MEG recordings were obtained at 5-, 10-, 20- and 30- week time points during tinnitus treatment. Results for the 500 Hz and 1000 Hz sources (where hearing thresholds were within normal limits for all participants showed that the tinnitus participants had a significantly larger and more anteriorly located source strengths when compared to the non-tinnitus participants. During the 30-week tinnitus treatment, the participants' 500 Hz and 1000 Hz source strengths remained higher than the non-tinnitus participants; however, the source locations shifted towards the direction recorded from the non-tinnitus control group. Further, in the left hemisphere, there was a time-shifted association between the trajectory of change of the individual's objective (source strength and anterior-posterior source location and subjective measures (using tinnitus reaction questionnaire, TRQ. The differences in source strength between the two groups suggest that individuals with tinnitus have enhanced central gain which is not significantly influenced by

  8. Cortical Reorganisation during a 30-Week Tinnitus Treatment Program

    Science.gov (United States)

    McMahon, Catherine M.; Ibrahim, Ronny K.; Mathur, Ankit

    2016-01-01

    Subjective tinnitus is characterised by the conscious perception of a phantom sound. Previous studies have shown that individuals with chronic tinnitus have disrupted sound-evoked cortical tonotopic maps, time-shifted evoked auditory responses, and altered oscillatory cortical activity. The main objectives of this study were to: (i) compare sound-evoked brain responses and cortical tonotopic maps in individuals with bilateral tinnitus and those without tinnitus; and (ii) investigate whether changes in these sound-evoked responses occur with amelioration of the tinnitus percept during a 30-week tinnitus treatment program. Magnetoencephalography (MEG) recordings of 12 bilateral tinnitus participants and 10 control normal-hearing subjects reporting no tinnitus were recorded at baseline, using 500 Hz, 1000 Hz, 2000 Hz, and 4000 Hz tones presented monaurally at 70 dBSPL through insert tube phones. For the tinnitus participants, MEG recordings were obtained at 5-, 10-, 20- and 30- week time points during tinnitus treatment. Results for the 500 Hz and 1000 Hz sources (where hearing thresholds were within normal limits for all participants) showed that the tinnitus participants had a significantly larger and more anteriorly located source strengths when compared to the non-tinnitus participants. During the 30-week tinnitus treatment, the participants’ 500 Hz and 1000 Hz source strengths remained higher than the non-tinnitus participants; however, the source locations shifted towards the direction recorded from the non-tinnitus control group. Further, in the left hemisphere, there was a time-shifted association between the trajectory of change of the individual’s objective (source strength and anterior-posterior source location) and subjective measures (using tinnitus reaction questionnaire, TRQ). The differences in source strength between the two groups suggest that individuals with tinnitus have enhanced central gain which is not significantly influenced by the

  9. Positive performance and health effects of a football training program over 12 weeks can be maintained over a 1-year period with reduced training frequency

    DEFF Research Database (Denmark)

    Randers, Morten Bredsgaard; Nielsen, Jens Jung; Krustrup, Birgitte Rejkjær

    2010-01-01

    We examined whether improvements in the performance and health profile of an intensive 12-week football intervention could be maintained with a reduced training frequency. Seventeen healthy untrained males completed the study. Ten subjects trained 2.4 times/week for 12 weeks and another 52 weeks ...... unaltered for CG. In conclusion, positive adaptations in cardiovascular fitness obtained over 12 weeks of regular recreational football training can be maintained over a 1-year period with a reduced training frequency, with further development in musculo-skeletal fitness.......We examined whether improvements in the performance and health profile of an intensive 12-week football intervention could be maintained with a reduced training frequency. Seventeen healthy untrained males completed the study. Ten subjects trained 2.4 times/week for 12 weeks and another 52 weeks...... (P12 weeks. After 64 weeks, quadriceps muscle mass (11%), mean fiber area (10%) and citrate synthase activity (18%) were higher (P

  10. Radiotherapy alone, versus radiotherapy with amifostine 3 times weekly, versus radiotherapy with amifostine 5 times weekly: A prospective randomized study in squamous cell head and neck cancer

    NARCIS (Netherlands)

    Jellema, Anke Petra; Slotman, Ben J.; Muller, Martin J.; Leemans, C. Rene; Smeele, Ludi E.; Hoekman, Klaas; Aaronson, Neil K.; Langendijk, Johannes A.

    2006-01-01

    BACKGROUND: The main objective of this study was to investigate whether nondaily intravenous administration of amifostine was as effective as daily intravenous administration with regard to the reduction of the incidence of Grade 2 or greater xerostomia in patients with head and neck cancer.

  11. Daily, weekly and annual patterns in children's accidental sport injuries.

    Science.gov (United States)

    Reinberg, Alain; Reinberg, Olivier; Mechkouri, Mohamed; Touitou, Yvan; Smolensky, Michael H

    2018-05-01

    Details of serious injuries to children ≤16 yrs. of age that necessitated urgent surgical intervention by the Department of Pediatric Surgery of the University Hospital of Lausanne, Switzerland were recorded into a database registry. Some 15 110 entries listed the precise time of injury, and 3114 (20.6%) of these resulted from participating in sport-associated activities. Time-of-day, day-of-week and month-of-year differences in the total number of children's accidental sport injuries (CASI) were validated. Time-of-day patterns were substantiated for "All Sports", for both boys and girls 5-16 yrs. of age, with more boys than girls experiencing incidents at almost every clock hour. Moreover, they were substantiated for this age group for each of the six different considered individual and team CASI categories - Physical Exercises at School; Bicycle Riding; Roller Skating and Skateboarding; Snow Skiing, Sledding, and Tobogganing; Soccer; and Basketball - for which sample sizes were sufficiently large (n > 230) to perform statistical assessment by ANOVA, t-test and/or cosinor analyses. CASI happened primarily between 06:00 and 17:00 h and rarely evening or overnight. Features - specific clock-time and number of peaks and troughs - of the CASI daily curve pattern of the individual six sport categories differed somewhat; nonetheless, excess or greatest number of CASI typically happened between 12:00 and 14:00 h, even when summertime and other scheduled school and family vacation periods were taken into account. Time-of-day and day-of-week patterns in the boy/girl sex ratio were also validated, with midday and Friday/Saturday peaks, respectively. We hypothesize the prominent 24 h patterns of CASI of 5-16 yr. olds, in particular, are representative of a combination of several determinants. These include exogenous periodic and cyclic environmental and sociocultural phenomena, genetic sex-related traits, plus endogenous circadian cognitive and physiologic rhythms

  12. 29 CFR 3.4 - Submission of weekly statements and the preservation and inspection of weekly payroll records.

    Science.gov (United States)

    2010-07-01

    ... inspection of weekly payroll records. 3.4 Section 3.4 Labor Office of the Secretary of Labor CONTRACTORS AND... STATES § 3.4 Submission of weekly statements and the preservation and inspection of weekly payroll... subcontractor, within seven days after the regular payment date of the payroll period, to a representative of a...

  13. Ultrasound Measurements of Thyroid Gland Volume at 36 Weeks' Corrected Gestational Age in Extremely Preterm Infants Born before 28 Weeks' Gestation.

    Science.gov (United States)

    Ng, Sze May; Turner, Mark A; Avula, Shivaram

    2018-01-01

    Thyroid ultrasound is a non-invasive imaging tool and provides good evaluation of thyroid anatomy, location, vascularisation, and echogenicity. The aim of this study was to assess thyroid function and thyroid volume in extremely preterm infants born before 28 weeks' gestation evaluated at 36 weeks' corrected gestational age (CGA) compared to term infants' normative data in the literature. In this largest prospective UK study of extremely premature infants born at less than 28 weeks' gestation, thyroid volume measurement was assessed at 36 weeks' CGA. Fifty-five extremely preterm infants (28 males) who were born before 28 weeks' gestation were recruited to the study. All infants had ultrasound assessment of the thyroid gland at 36 weeks' CGA. We also prospectively measured thyroid stimulating hormone (TSH) and free thyroxine (FT 4 ) in all infants at the time of recruitment (within 5 days of birth), at days 14, 21, and 28, and at 36 weeks' CGA. The mean thyroid volume was measured at 0.57 mL (SD ±0.18). There was no association between mean thyroid volume and thyroid function (TSH or FT 4 ). No associations were found between mean thyroid volume and gestation or birth weight in these infants. Our findings provide a reference range with a mean thyroid volume of 0.57 mL (SD ±0.18) in this extremely preterm age group if less than 28 weeks' gestation. Thyroid volume at birth can vary from country to country due to variations in iodine intake as well as gestational age.

  14. A novel needle for subcutaneous injection of interferon beta-1a: effect on pain in volunteers and satisfaction in patients with multiple sclerosis

    Directory of Open Access Journals (Sweden)

    Prais Wes A

    2008-10-01

    Full Text Available Abstract Background To reduce injection pain and improve satisfaction, a thinner (29-gauge [29G], sharper (5-bevel needle than the 27G/3-bevel needle used previously to inject interferon (IFN beta-1a, 44 or 22 mcg subcutaneously (sc three times weekly (tiw, was developed for use in multiple sclerosis (MS. Methods Two clinical trials in healthy volunteers and five surveys of patients with MS were conducted to assess whether the 29G/5-bevel needle with a Thermo Plastic Elastomer (TPE needle shield (a sleeve that houses the tip of the needle in a secure location is an improvement over the 27G/3-bevel needle with a rubber shield for injection of IFN beta-1a, 44 or 22 mcg sc tiw. Parameters assessed were: pain and ease of insertion (healthy volunteer and nurse responses on subjective pain measurement scales; and patient satisfaction (surveys of patients with MS. Results In healthy volunteers, the 29G/5-bevel needle with TPE shield was associated with the least perceived pain on the Visual Analog Scale (VAS and Verbal VAS (VB-VAS; mean VAS pain scores decreased by 40% and skin penetration improved by 69% compared with the 27G/3-bevel needle with standard rubber shield (p Conclusion Together these studies indicate that the 29G/5-bevel needle with the TPE shield is an improvement over the 27G/3-bevel needle with standard rubber shield in terms of pain, ease of insertion and patient satisfaction. These improvements are expected to result in improved compliance in patients with MS treated with IFN beta-1a, 44 or 22 mcg sc tiw.

  15. The Effects of a 6-Week Plyometric Training Program on Agility

    OpenAIRE

    Miller, Michael G.; Herniman, Jeremy J.; Ricard, Mark D.; Cheatham, Christopher C.; Michael, Timothy J.

    2006-01-01

    The purpose of the study was to determine if six weeks of plyometric training can improve an athlete's agility. Subjects were divided into two groups, a plyometric training and a control group. The plyometric training group performed in a six week plyometric training program and the control group did not perform any plyometric training techniques. All subjects participated in two agility tests: T-test and Illinois Agility Test, and a force plate test for ground reaction times both pre and pos...

  16. Final report on Weeks Island Monitoring Phase : 1999 through 2004.

    Energy Technology Data Exchange (ETDEWEB)

    Ehgartner, Brian L.; Munson, Darrell Eugene

    2005-05-01

    This Final Report on the Monitoring Phase of the former Weeks Island Strategic Petroleum Reserve crude oil storage facility details the results of five years of monitoring of various surface accessible quantities at the decommissioned facility. The Weeks Island mine was authorized by the State of Louisiana as a Strategic Petroleum Reserve oil storage facility from 1979 until decommissioning of the facility in 1999. Discovery of a sinkhole over the facility in 1992 with freshwater inflow to the facility threatened the integrity of the oil storage and led to the decision to remove the oil, fill the chambers with brine, and decommission the facility. Thereafter, a monitoring phase, by agreement between the Department of Energy and the State, addressed facility stability and environmental concerns. Monitoring of the surface ground water and the brine of the underground chambers from the East Fill Hole produced no evidence of hydrocarbon contamination, which suggests that any unrecovered oil remaining in the underground chambers has been contained. Ever diminishing progression of the initial major sinkhole, and a subsequent minor sinkhole, with time was verification of the response of sinkholes to filling of the facility with brine. Brine filling of the facility ostensively eliminates any further growth or new formation from freshwater inflow. Continued monitoring of sinkhole response, together with continued surface surveillance for environmental problems, confirmed the intended results of brine pressurization. Surface subsidence measurements over the mine continued throughout the monitoring phase. And finally, the outward flow of brine was monitored as a measure of the creep closure of the mine chambers. Results of each of these monitoring activities are presented, with their correlation toward assuring the stability and environmental security of the decommissioned facility. The results suggest that the decommissioning was successful and no contamination of the

  17. Weekly Cycle of Lightning: Evidence of Storm Invigoration by Pollution

    Science.gov (United States)

    Bell, Thomas L.; Rosenfeld, Daniel; Kim, Kyu-Myong

    2009-01-01

    We have examined summertime 1998 2009 U.S. lightning data from the National Lightning Detection Network (NLDN) to look for weekly cycles in lightning activity. As was found by Bell et al. (2008) for rain over the southeast U.S., there is a significant weekly cycle in afternoon lightning activity that peaks in the middle of the week there. The weekly cycle appears to be reduced over population centers. Lightning activity peaks on weekends over waters near the SE U.S. The statistical significance of weekly cycles over the western half of the country is generally small. We found no evidence of a weekly cycle of synoptic-scale forcing that might explain these patterns. The lightning behavior is entirely consistent with the explanation suggested by Bell et al. (2008) for the cycles in rainfall and other atmospheric data from the SE U.S., that aerosols can cause storms to intensify in humid, convectively unstable environments.

  18. CGH observes National Women’s Health Week

    Science.gov (United States)

    This week, the U.S. Department of Health and Human Services is observing the 17th annual National Women’s Health Week. The goal of the National Women's Health Week is to empower women to make their health a priority. In celebration, the NCI Center for Global Health held a seminar on the Knowledge Summaries for Comprehensive Breast Cancer Control: Pathways for Advanced Cancer Planning.

  19. Five-Week Outcomes From a Dosing Trial of Therapeutic Massage for Chronic Neck Pain

    Science.gov (United States)

    Sherman, Karen J.; Cook, Andrea J.; Wellman, Robert D.; Hawkes, Rene J.; Kahn, Janet R.; Deyo, Richard A.; Cherkin, Daniel C.

    2014-01-01

    PURPOSE This trial was designed to evaluate the optimal dose of massage for individuals with chronic neck pain. METHODS We recruited 228 individuals with chronic nonspecific neck pain from an integrated health care system and the general population, and randomized them to 5 groups receiving various doses of massage (a 4-week course consisting of 30-minute visits 2 or 3 times weekly or 60-minute visits 1, 2, or 3 times weekly) or to a single control group (a 4-week period on a wait list). We assessed neck-related dysfunction with the Neck Disability Index (range, 0–50 points) and pain intensity with a numerical rating scale (range, 0–10 points) at baseline and 5 weeks. We used log-linear regression to assess the likelihood of clinically meaningful improvement in neck-related dysfunction (≥5 points on Neck Disability Index) or pain intensity (≥30% improvement) by treatment group. RESULTS After adjustment for baseline age, outcome measures, and imbalanced covariates, 30-minute treatments were not significantly better than the wait list control condition in terms of achieving a clinically meaningful improvement in neck dysfunction or pain, regardless of the frequency of treatments. In contrast, 60-minute treatments 2 and 3 times weekly significantly increased the likelihood of such improvement compared with the control condition in terms of both neck dysfunction (relative risk = 3.41 and 4.98, P = .04 and .005, respectively) and pain intensity (relative risk = 2.30 and 2.73; P = .007 and .001, respectively). CONCLUSIONS After 4 weeks of treatment, we found multiple 60-minute massages per week more effective than fewer or shorter sessions for individuals with chronic neck pain. Clinicians recommending massage and researchers studying this therapy should ensure that patients receive a likely effective dose of treatment. PMID:24615306

  20. Bioelectrical activity of the pelvic floor muscles after 6-week biofeedback training in nulliparous continent women.

    Science.gov (United States)

    Chmielewska, Daria; Stania, Magdalena; Smykla, Agnieszka; Kwaśna, Krystyna; Błaszczak, Edward; Sobota, Grzegorz; Skrzypulec-Plinta, Violetta

    2016-01-01

    The aim of the study was to evaluate the effects of a 6-week sEMG-biofeedback-assisted pelvic floor muscle training program on pelvic floor muscle activity in young continent women. Pelvic floor muscle activity was recorded using a vaginal probe during five experimental trials. Biofeedback training was continued for 6 weeks, 3 times a week. Muscle strenghtening and endurance exercises were performed alternately. SEMG (surface electromyography) measurements were recorded on four different occasions: before training started, after the third week of training, after the sixth week of training, and one month after training ended. A 6-week sEMG-biofeedback-assisted pelvic floor muscle training program significantly decreased the resting activity of the pelvic floor muscles in supine lying and standing. The ability to relax the pelvic floor muscles after a sustained 60-second contraction improved significantly after the 6-week training in both positions. SEMG-biofeedback training program did not seem to affect the activity of the pelvic floor muscles or muscle fatigue during voluntary pelvic floor muscle contractions. SEMG-biofeedback-assisted pelvic floor muscle training might be recommended for physiotherapists to improve the effectiveness of their relaxation techniques.

  1. Twenty weeks of isometric handgrip home training to lower blood pressure in hypertensive older adults

    DEFF Research Database (Denmark)

    Jørgensen, Martin Grønbech; Ryg, Jesper; Danielsen, Mathias Brix

    2018-01-01

    lower blood pressure levels beyond the 10-week mark. Recently, we developed a novel method for monitoring handgrip intensity using a standard Nintendo Wii Board (Wii). The primary aim of this study is to explore the effects of a 20-week IHG home training facilitated by a Wii in hypertensive older adults......) or to a control group (hypertension guidelines on lifestyle changes). Participants in the intervention group will perform IHG home training (30% of maximum grip strength for a total of 8 min per day per hand) three times a week for 20 weeks. Resting blood pressure and maximal handgrip strength will be obtained......BACKGROUND: Hypertension markedly increases the risk of cardiovascular diseases and overall mortality. Lifestyle modifications, such as increased levels of physical activity, are recommended as the first line of anti-hypertensive treatment. A recent systematic review showed that isometric handgrip...

  2. Overuse and traumatic extremity injuries in schoolchildren surveyed with weekly text messages over 2.5 years

    DEFF Research Database (Denmark)

    Jespersen, E; Holst, R; Franz, C

    2014-01-01

    phone text message asking questions on the presence of any musculo-skeletal problems and participation in leisure-time sport. Children were examined and injuries classified as overuse or traumatic. The overall injury incidence and prevalence were 1.2% and 4.6% per week, with 2.5 times more overuse than...... traumatic injuries in lower extremities, and mean injury duration of 5.3 and 4.8 weeks, respectively. A reverse pattern was found for upper extremities, with 3.1 times more traumatic than overuse injuries and mean durations of 3.3 and 5.2 weeks, respectively. Grade level, school type, leisure-time sport...

  3. 77 FR 31143 - Emergency Medical Services Week, 2012

    Science.gov (United States)

    2012-05-24

    ... Business Week, 2012 Proclamation 8827--World Trade Week, 2012 Executive Order 13612--Providing an Order of Succession Within the Department of Agriculture Executive Order 13613--Providing an Order of Succession Within the Department of Commerce Executive Order 13614--Providing an Order of Succession Within the...

  4. The Effect of Weekly Progress Reports on Academic Achievement.

    Science.gov (United States)

    Armour, Katherine S.

    This study investigated the effect of weekly progress reports on the academic achievement of seventh grade language arts students. It also investigated the effects of weekly progress reports on locus of control attribution and the relationship between academic achievement and locus of control attribution. The study took place in a suburban school…

  5. Improvement in Running Economy after 6 Weeks of Plyometric Training.

    Science.gov (United States)

    Turner, Amanda M.; Owings, Matt; Schwane, James A.

    2003-01-01

    Investigated whether a 6-week regimen of plyometric training would improve running economy. Data were collected on 18 regular but not highly trained distance runners who participated in either regular running training or plyometric training. Results indicated that 6 weeks of plyometric training improved running economy at selected speeds in this…

  6. 7 CFR 59.302 - Mandatory weekly reporting for lambs.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false Mandatory weekly reporting for lambs. 59.302 Section... (CONTINUED) LIVESTOCK MANDATORY REPORTING Lamb Reporting § 59.302 Mandatory weekly reporting for lambs. (a... domestic from imported market purchases: (1) The quantity of lambs purchased through a negotiated purchase...

  7. 77 FR 65095 - National Forest Products Week, 2012

    Science.gov (United States)

    2012-10-24

    ... October 27, 2012, as National Forest Products Week. I call on the people of the United States to join me... National Forest Products Week, 2012 By the President of the United States of America A Proclamation Since... tourism and recreation that create jobs and growth in our rural communities. They provide the raw...

  8. Choose Privacy Week: Educate Your Students (and Yourself) about Privacy

    Science.gov (United States)

    Adams, Helen R.

    2016-01-01

    The purpose of "Choose Privacy Week" is to encourage a national conversation to raise awareness of the growing threats to personal privacy online and in day-to-day life. The 2016 Choose Privacy Week theme is "respecting individuals' privacy," with an emphasis on minors' privacy. A plethora of issues relating to minors' privacy…

  9. The Four Day Week: An Alternative School Calendar.

    Science.gov (United States)

    Pope, Jean; Gillian, Russ

    This booklet surveys the possibilities in instituting a 4-day school week, an approach which has gained favor in some small school districts. The history of the 4-day week and its characteristics are first described. Drawing on case studies of districts that have begun the 4-day schedule, the authors enumerate the steps in proposing and…

  10. 78 FR 30727 - Emergency Medical Services Week, 2013

    Science.gov (United States)

    2013-05-22

    .... During Emergency Medical Services Week, we pause to offer our gratitude to these remarkable men and women, whose dedication is fundamental to our society's well-being. In recent weeks, we have again seen the... thousand thirteen, and of the Independence of the United States of America the two hundred and thirty...

  11. Weekly paclitaxel with concurrent radiotherapy followed by adjuvant chemotherapy in locally advanced nasopharyngeal carcinoma

    International Nuclear Information System (INIS)

    Hu Wei; Ding Weijun; Yang Haihua; Shao Minghai; Wang Biyun; Wang Jianhua; Wu Sufang; Wu Shixiu; Jin Lihui; Ma, Charlie C.-M.

    2009-01-01

    Purpose: To evaluate the efficacy and toxicity of weekly paclitaxel with concurrent radiotherapy followed by adjuvant chemotherapy (AC) in patients with locally advanced nasopharyngeal carcinoma (NPC). Methods and materials: Between 2004 and 2007, 54 patients with locally advanced NPC were included in this protocol. Patient characteristics: median age 48; 69% male; 52% World Health Organization (WHO) III; 50% stage III, 50% stage IV. The patients underwent a course of definitive conventional radiotherapy (70 Gy in 7 weeks with 2 Gy/fraction), with concurrent weekly paclitaxel 35 mg/m 2 from the first to the sixth week of radiation. AC was started 4 weeks after the end of the radiotherapy (RT), paclitaxel 135 mg/m 2 on day 1 and cisplatin 30 mg/m 2 on days 1-3 were administered every 4 weeks for two cycles. Results: Median follow-up was 32 months. Eighty-five percentage of complete response and 15% partial response were achieved at the time of one month after AC. The 3-year actuarial rate of local regional control was 86%; distant metastases-free survival, progression-free survival and overall survival at 3 years were 81%, 69% and 76%, respectively. Forty-nine (91%) patients completed six courses of concurrent chemotherapy with weekly paclitaxel, and 4 (7%) patients delayed at the second cycle of AC. No patient developed severe acute toxicities. Conclusions: Weekly paclitaxel with concurrent RT followed by AC is a potentially effective and toxicity tolerable method for locally advanced NPC. Further studies are needed to identify the optimal dose of weekly paclitaxel in this strategy.

  12. EE-drospirenone-levomefolate calcium versus EE-drospirenone + folic acid: folate status during 24 weeks of treatment and over 20 weeks following treatment cessation

    Directory of Open Access Journals (Sweden)

    Diefenbach K

    2013-04-01

    Full Text Available Konstanze Diefenbach,1 Dietmar Trummer,1 Frank Ebert,1 Michael Lissy,2 Manuela Koch,2 Beate Rohde,1 Hartmut Blode3 1Bayer HealthCare Pharmaceuticals, Berlin, Germany; 2Nuvisan GmbH, Neu-Ulm, Germany; 3Bayer HealthCare Pharmaceuticals Global R&D Center, Beijing, People's Republic of China Background: Adequate folate supplementation in the periconceptional phase is recommended to reduce the risk of neural tube defects. Oral contraceptives may provide a reasonable delivery vehicle for folate supplementation before conception in women of childbearing potential. This study aimed to demonstrate that a fixed-dose combination of an oral contraceptive and levomefolate calcium leads to sustainable improvements in folate status compared with an oral contraceptive + folic acid. Methods: This was a double-blind, randomized, parallel-group study in which 172 healthy women aged 18–40 years received ethinylestradiol (EE-drospirenone-levomefolate calcium or EE-drospirenone + folic acid for 24 weeks (invasion phase, and EE-drospirenone for an additional 20 weeks (folate elimination phase. The main objective of the invasion phase was to examine the area under the folate concentration time-curve for plasma and red blood cell (RBC folate, while the main objective of the elimination phase was to determine the duration of time for which RBC folate concentration remained ≥ 906 nmol/L after cessation of EE-drospirenone-levomefolate calcium. Results: Mean concentration-time curves for plasma folate, RBC folate, and homocysteine were comparable between treatment groups during both study phases. During the invasion phase, plasma and RBC folate concentrations increased and approached steady-state after about 8 weeks (plasma or 24 weeks (RBC. After cessation of treatment with levomefolate calcium, folate concentrations decreased slowly. The median time to RBC folate concentrations falling below 906 nmol/L was 10 weeks (95% confidence interval 8–12 weeks after cessation

  13. Medical image of the week: acute amiodarone pulmonary toxicity

    Directory of Open Access Journals (Sweden)

    Mazursky K

    2015-10-01

    Full Text Available No abstract available. Article truncated after 150 words. A 71 year old man with a medical history significant for chronic obstructive pulmonary disease, coronary artery disease with post-operative status coronary artery bypass grafting, heart failure with reduced ejection fraction (25% and atrial fibrillation/flutter underwent an elective ablation of the tachyarrhythmia at another facility and was prescribed amiodarone post procedure. He started complaining of cough and dyspnea one day post procedure and was empirically treated with 2 weeks of broad spectrum antibiotics. He subsequently was transferred to our facility due to worsening symptoms. He also complained of nausea, anorexia with resultant weight loss since starting amiodarone, which was stopped 5 days prior to transfer. Infectious work up was negative. On arrival to our facility, he was diagnosed with small sub-segmental pulmonary emboli, pulmonary edema and possible acute amiodarone toxicity. His was profoundly hypoxic requiring high flow nasal cannula or 100% non-rebreather mask at all times. His symptoms persisted despite ...

  14. Weeks Island gravity stable CO2 pilot: Final report

    Energy Technology Data Exchange (ETDEWEB)

    Johnston, J.R.; Perry, G.E.

    1989-01-01

    The Weeks Island ''S'' sand Reservoir B (''S'' RB) gravity-stable CO2 field test was completed during February 1988. Injection started in October 1978 and production began in January 1981 in this high-permeability, steeply-dipping sandstone reservoir. About 264,000 barrels of oil or 65 percent of the starting volume has been recovered. A 24-percent pore-volume slug of CO2 mixed with about six mole percent of natural gas (mostly methane) was injected at the start of the pilot. Since 1983, produced CO2 plus hydrocarbon gases have been recycled. CO2 usage statistics are 9.34 MCF/BO with recycle and 3.24 MCF/BO based on purchased CO2. Previous annual reports document the pilot design, implementation, and early results for the 1977 to June 1981 time period. This report is a review of early pilot history and a more detailed account of the post June 1981 results and overall interpretation. A reservoir-simulation history match of pilot performance plus core and log data from a 1983 swept-zone evaluation well are described in this report. A brief description of the production facility and an account of the corrosion control program are also included. 11 refs., 34 figs.

  15. The Physics session at the ATLAS overview week

    CERN Multimedia

    Takai, H.

    The Physics session at the ATLAS overview week at Clermont-Ferrand will be certainly remembered by the presentation of Blaise Pascal's historical experiment repeat. And why not? He is the local hero and by the looks of his primitive measurements it does take a lot of guts to explain his results on the basis of air columns. He was also lucky that he did not have to simulate his results on modern day computers but used the Pascaline. Certainly a man ahead of his time. Of course that wasn't all. Surrounded by a chain of (luckily) extinct volcanoes, rolling hills, and superb views, Clermont-Ferrand provided the perfect backdrop for the physics discussions. It was once more seen that the physics of ATLAS is diverse and that it is healthy and doing well. Many people contributed to the success of the session. Fabiola started the session precisely at 14:00 with a summary of the most recent activities from the physics coordination. Somehow what got stuck in my mind was the very positive statistics on how many prese...

  16. Weekly and Twice-Weekly Yoga Classes Offer Similar Low-Back Pain Relief in Low-Income Minority Populations

    Science.gov (United States)

    ... Weekly and Twice-Weekly Yoga Classes Offer Similar Low-Back Pain Relief in Low-Income Minority Populations Share: © Photodisc ... in minority and low-income populations with chronic low-back pain. Researchers from Boston University School of Medicine, Boston ...

  17. Targeted ultraviolet B phototherapy in vitiligo: A comparison between once-weekly and twice-weekly treatment regimens

    Directory of Open Access Journals (Sweden)

    Imran Majid

    2015-01-01

    Full Text Available Background: Targeted ultraviolet B (T-UVB phototherapy in vitiligo is usually administered twice or thrice a week on non-consecutive days. It is difficult for many patients to adhere to this regimen, forcing them to discontinue treatment. Aim: The study aimed to compare the efficacy of twice-weekly and once-weekly targeted ultraviolet B phototherapy regimens in vitiligo. Methods: Sixty patients with non-segmental vitiligo on the face, neck or trunk were divided into two groups of 30 patients each. The patients in group A received targeted ultraviolet B twice weekly, while those in group B received targeted ultraviolet B once weekly. Repigmentation was monitored and graded as excellent (≥75% repigmentation, good (50−74% repigmentation and poor (<50% repigmentation. The extent of repigmentation at each body site (primary outcome measure, the number of doses required for initiation of pigmentation, and the cumulative dose of targeted ultraviolet B administered was calculated and compared between both groups. Results: A total of 90 lesions (48 in the twice weeklygroup and 42 in the once weekly group were treated on the face, neck and trunk. Excellent results were obtained in 62.5% (30/48 of lesions treated twice weekly, and 64.3% (27/42 in lesions treated once weekly. The mean number of doses required for initiation of pigmentation was 4.69 in the twice weekly group, and 4.35 in the once weekly group. The patients in the twice weekly group received a mean cumulative dose of 8.26 J/cm 2, while the once weekly group received 7.69 J/cm 2. No statistically significant differences were observed between the two groups with respect to the outcome, with respect to the total repigmentation, the number of doses till onset of pigmentation, as well as the cumulative dose of targeted UVB. Conclusion: Once-weekly targeted ultraviolet B phototherapy appears to be as efficacious as the twice-weekly regimen in vitiligo.

  18. The effect of 8-week low impact aerobic exercise on plasma fibrinogen concentration in old women

    Directory of Open Access Journals (Sweden)

    Shahla Dehghan

    2013-09-01

    Full Text Available Applied Exercise Physiology focuses on the physiological effects of exercise training on physiological processes, health, and physical well-being. The aim of this study was investigation of effects of 8-week low impact aerobic exercise on plasma fibrinogen concentration in old women. Fibrinogen is one of the most important inflammation factors and a prediction index in cardio vascular diseases. Iranian women especially older ones are generally sedentary because of their traditional and religious believes. Samples were 23 healthy and enable to do physical activity old women of Shahrekord (Chaharmahal va bakhtiary province, Iran retirement home. Subjects were randomly divided to two groups including experimental (n=14 individuals and control (n=11 individuals. First, for assessment of fibrinogen level, 5cc blood samples were obtained after 8 hours nightly fasting from anterior vein in resting condition. Experimental group was participated in 8 week (three times a week LIA training program (15 min in first day with 40% of maximum heart rate until 40 min in last day with 65% of maximum heart rate. All of mentioned measurements repeated at the end of 8 week training. The obtained results showed that 8 week LIA program has significant effect on reduction of old women plasma fibrinogen level (P=0.02. It seems that use of 8 week LIA training has positive effects on improvement of cardiovascular health and prevention of inflammation disease related to plasma fibrinogen level in Iranian old women. Key words: aerobic exercises, old women, fibrinogen.

  19. Histochemical responses of rats exercised in two weekly frequencies and ingesting standard or hypercaloric diet

    Directory of Open Access Journals (Sweden)

    FI Freitas

    2009-07-01

    Full Text Available This study investigated if overfed rats present morphological and histochemical muscle adaptation similar to normally fed, both submitted to two different weekly frequencies of training. Thirty male Wistar rats were fed either with standard chow (SCØ or with hypercaloric diet (HCØ. They were subdivided into six subgroups: sedentary (SCØ and HCØ, trained twice/week (SC2 and HC2 and trained five times/week (SC5 and HC5. The trained groups swam 60 min/day, during 10 weeks. Twenty four hours after the last training, samples of Gastrocnemius were excised and stained with HE, NADH-TR and m-ATPase, and the capillary density was calculated. Total heart mass (HM and the mass of atrium (AM, left (LV and right (RV ventricles were excised and weighted. The comparisons were made by ANOVA and by Covariance analysis, adjusting the variables by body weight. The results showed that the HCØ achieved higher BM, however, absolute HM did not differ post training. Irrespective of the diet, rats that were trained twice a week presented significantly greater increase in the AM. In general, the SC5 and HC5 groups showed higher HM, LV, RV, proportion of oxidative fibres and capillary density, compared to the sedentary and twice week trained groups. A higher proportion of injuries (splitting was noted in the HC2 and HC5 compared to SC2 and SC5. These results indicate that the frequency of training influenced the skeletal and heart adaptation and larger changes were observed in the 5x/week group, which ingested the standard diet. The 5x/week training groups also presented large amount of muscle fibres damage.

  20. Coral Reef Watch, Degree Heating Weeks, 50 km

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA Coral Reef Watch distributes Degree Heating Week products using a combination of the POES AVHRR Global Area Coverage data, and data from a climatological...

  1. Tallinn Fashion Week algas moeillustraatorite näitusega

    Index Scriptorium Estoniae

    2011-01-01

    Näitus "Uus Põhjamaade moeillustratsioon" Rotermanni kvartalis 18. sept.-ni. Osalejad Eestist, Soomest ja Rootsist loetletud. Näituse kujundaja Tuuli Aule. Väljapaneku loovjuhi Toomas Volkmanni selgitus. Tallinn Fashion Week'i põhiprogrammist

  2. Factors associated with adequate weekly reporting for disease ...

    African Journals Online (AJOL)

    IDSR) strategy in 1998 to strengthen disease surveillance and epidemic response. However, the goal of weekly surveillance reporting among health facilities has not been achieved. We conducted a crosssectional study to determine the ...

  3. Virginia Tech recognizes National Farm Safety and Health Week

    OpenAIRE

    Sutphin, Michael D.

    2006-01-01

    Virginia Tech's College of Agriculture and Life Sciences and Virginia Cooperative Extension are observing National Farm Safety and Health Week, Sept. 18-22. This week commemorates the hard work, diligence, and sacrifices of our nation's farmers and ranchers and dovetails the announcement of an $800,000 grant to improve the lives of Virginia's farmers, their families, and those who live in rural communities.

  4. The Good, the Bad, and the 30 Hour Work Week

    OpenAIRE

    Sneberg, Ann Kristin; Andersen, Amalie Elizabeth Thune

    2016-01-01

    This project investigates why it is that an initiative such as 30 hour work weeks has not been morewidely implemented in organisations. The topic of stress and imbalance between work life andpersonal life seems to be growing more and more. Furthermore, the effects of the traditionalbusiness approach are being seen more and more on the environment. Therefore, there wouldappear to be a need for change. Yet, why is it, that when a suggestion such as reducing standardworking weeks to 30 hours, in...

  5. Seasonal Differences in the Day-of-the-Week Pattern of Suicide in Queensland, Australia

    Science.gov (United States)

    Law, Chi-kin; De Leo, Diego

    2013-01-01

    Various temporal patterns of suicide events, according to time of day, day of week, month and season, have been identified. However, whether different dimensions of time interact has not been investigated. Using suicide data from Queensland, Australia, this study aims to verify if there is an interaction effect between seasonal and day-of-the-week distribution. Computerized suicide data from the Queensland Suicide Register for those aged 15+ years were analyzed according to date of death, age, sex and geographic location for the period 1996–2007. To examine seasonal differences in day-of-the-week pattern of suicide, Poisson regressions were used. A total of 6,555 suicides were recorded over the whole study period. Regardless of the season, male residents of Brisbane had a significantly marked day-of-the-week pattern of suicide, with higher rates between Mondays and Thursdays. When seasonal differences were considered, male residents in Brisbane showed a Monday peak in summer and a wave-shape pattern with a peak on Thursday and a nadir on Saturdays in winter. Whilst males have distinctive peaks in terms of days of the week for summer and winter, females do not show similar patterns. PMID:23880724

  6. Negative Input for Grammatical Errors: Effects after a Lag of 12 Weeks

    Science.gov (United States)

    Saxton, Matthew; Backley, Phillip; Gallaway, Clare

    2005-01-01

    Effects of negative input for 13 categories of grammatical error were assessed in a longitudinal study of naturalistic adult-child discourse. Two-hour samples of conversational interaction were obtained at two points in time, separated by a lag of 12 weeks, for 12 children (mean age 2;0 at the start). The data were interpreted within the framework…

  7. 77 FR 29529 - Peace Officers Memorial Day and Police Week, 2012

    Science.gov (United States)

    2012-05-18

    ... Officers Memorial Day and Police Week, 2012 By the President of the United States of America A Proclamation... time, this new system will give our Nation's police officers and first responders a dedicated... obligation to give their loved ones the support they deserve. During Peace Officers Memorial Day and Police...

  8. Obesity-related beliefs predict weight loss after an 8-week low-calorie diet

    NARCIS (Netherlands)

    Wamsteker, E.W.; Geenen, R.; Iestra, J.A.; Larsen, J.K.; Zelissen, P.M.J.; Staveren, van W.A.

    2005-01-01

    The objective of this study was to examine whether beliefs about the cause, consequences, time line, and control of obesity are predictors of the amount of weight loss after an 8-week, low-calorie diet consisting of meal replacements. Forty-eight women and 18 men, mean age=45.9 (range=23 to 73

  9. 3 CFR 8432 - Proclamation 8432 of October 2, 2009. Fire Prevention Week, 2009

    Science.gov (United States)

    2010-01-01

    .... Fire Prevention Week is a time to learn about important fire safety issues and empower our communities... in their homes and workplaces. We can greatly reduce these tragedies by taking a few, very simple... of fire, we honor the brave men and women who protect us from it, and we recommit ourselves to its...

  10. Advanced non-small cell lung cancer in elderly patients: The standard every 3-weeks versus weekly paclitaxel with carboplatin

    Directory of Open Access Journals (Sweden)

    Hala Mohamed El-Shenshawy

    2012-10-01

    Conclusions: Efficacy was similar between the weekly regimen and the standard regimen of carboplatin and paclitaxel for elderly patients with advanced NSCLC and may be advantageous based on its favorable tolerability profile.

  11. Rapid decline in glomerular filtration rate during the first weeks following heart transplantation

    DEFF Research Database (Denmark)

    Hornum, M; Andersen, M; Gustafsson, F

    2011-01-01

    We hypothesized that a decrease in renal function is seen immediately after heart transplantation (HTX) with little recovery over time. Twelve consecutive patients had their glomerular filtration rate (GFR) measured using (51)Cr-ethylenediaminetetraacetic acid (EDTA) measured GFR (mGFR) before...... transplantation and at 1, 2, 3, and 26 weeks after transplantation. The mGFR decreased by 28% and 24% during the first 3 and 26 weeks, respectively, with mean blood cyclosporine concentration as an independent risk factor for the decrease in mGFR. The identification of cyclosporine A (CsA) as the most important...

  12. Historical Review of the Transportation Analysis Fact of the Week, 1996-2017

    Energy Technology Data Exchange (ETDEWEB)

    Gohlke, David [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Davis, Stacy Cagle [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2017-10-01

    The Vehicle Technologies Office in the United States Department of Energy hosts a transportation analysis fact of the week on its webpage. As of October 2017, one thousand facts have been published since 1996. Examining the themes of published facts allows one to trace analytical trends determined to be of interest to the public over this time. The most popular themes addressed in the Fact of the Week were vehicle fuel economy, petroleum use and production, vehicle sales, and traveler behavior. Facts on vehicle electrification and advanced combustion technologies have been more popular in the last few years, showing their relevance to the Department of Energy mission.

  13. Night work, long work weeks, and risk of accidental injuries. A register-based study.

    Science.gov (United States)

    Larsen, Ann D; Hannerz, Harald; Møller, Simone V; Dyreborg, Johnny; Bonde, Jens Peter; Hansen, Johnni; Kolstad, Henrik A; Hansen, Åse Marie; Garde, Anne Helene

    2017-11-01

    Objectives The aims of this study were to (i) investigate the association between night work or long work weeks and the risk of accidental injuries and (ii) test if the association is affected by age, sex or socioeconomic status. Methods The study population was drawn from the Danish version of the European Labour Force Survey from 1999-2013. The current study was based on 150 438 participants (53% men and 47% women). Data on accidental injuries were obtained at individual level from national health registers. We included all 20-59-year-old employees working ≥32 hours a week at the time of the interview. We used Poisson regression to estimate the relative rates (RR) of accidental injuries as a function of night work or long work weeks (>40 hours per week) adjusted for year of interview, sex, age, socioeconomic status (SES), industry, and weekly working hours or night work. Age, sex and SES were included as two-way interactions. Results We observed 23 495 cases of accidental injuries based on 273 700 person years at risk. Exposure to night work was statistically significantly associated with accidental injuries (RR 1.11, 99% CI 1.06-1.17) compared to participants with no recent night work. No associations were found between long work weeks (>40 hours) and accidental injuries. Conclusion We found a modest increased risk of accidental injuries when reporting night work. No associations between long work weeks and risk of accidental injuries were observed. Age, sex and SES showed no trends when included as two-way interactions.

  14. Variability of skin autofluorescence measurement over 6 and 12 weeks and the influence of benfotiamine treatment.

    Science.gov (United States)

    Stirban, Alin; Pop, Alexandra; Fischer, Annelie; Heckermann, Sascha; Tschoepe, Diethelm

    2013-09-01

    Measurements of skin autofluorescence (SAF) allow for a simple and noninvasive quantification of tissue advanced glycation end-products (AGEs), a marker linked to the risk of diabetes complications. The aim of this study was to test the repeatability of SAF over 6 and 12 weeks and to test whether benfotiamine, a thiamine prodrug suggested to reduce AGEs formation under hyperglycemic conditions, is able to attenuate SAF when administered over 6 weeks. In a double-blind, placebo-controlled, randomized, crossover study, 22 patients with type 2 diabetes mellitus (T2DM) received 900 mg/day benfotiamine or placebo for 6 weeks (washout period of 6 weeks between). At the beginning and at the end of each treatment period, SAF was assessed in the fasting state, as well as 2, 4, and 6 h following a mixed test meal. The respective intra-individual and inter-individual variability of fasting SAF was 6.9% and 24.5% within 6 weeks and 10.9% and 23.1% within 12 weeks. The respective variability calculated for triplicate comparisons was 9.9% and 27.7%. A short-term therapy with benfotiamine did not influence SAF significantly, nor did we find a significant postprandial SAF increase. In patients with T2DM, repeated, timely spaced SAF measurements have an intra-subject variability of below 11%. Using these data, sample sizes were calculated for interventional studies aiming at reducing SAF. Benfotiamine treatment for 6 weeks did not significantly influence SAF; for this, a longer-term therapy is probably needed.

  15. Phlebotomy eliminates the maximal cardiac output response to six weeks of exercise training

    DEFF Research Database (Denmark)

    Bonne, Thomas Christian; Doucende, Gregory; Flück, Daniela

    2014-01-01

    With this study we tested the hypothesis that six weeks of endurance training increases maximal cardiac output (Qmax) relatively more by elevating blood volume (BV) than by inducing structural and functional changes within the heart. Nine healthy but untrained volunteers (VO2max 47 ± 5 ml.min(-1......).kg(-1)) underwent supervised training (60 min; 4 times weekly at 65% VO2max for six weeks) and Qmax was determined by inert gas re-breathing during cycle ergometer exercise before and after the training period. After the training period, blood volume (determined in duplicates by CO re......-breathing) was re-established to pre-training values by phlebotomy and Qmax was quantified again. Resting echography revealed no structural heart adaptations as a consequence of the training intervention. Following the training period, plasma volume (PV), red blood cell volume (RBCV) and BV increased (p...

  16. Turning breech babies after 34 weeks: the if, how, & when of turning breech babies.

    Science.gov (United States)

    Cohain, Judy Slome

    2007-01-01

    Techniques for turning a term breech baby are 1). External cephalic version (ECV) using hands and ultrasound only; 2). Acupuncture point stimulation, by needle or moxibustion; 3). Chiropractic "Webster" technique; 4). Hypnotherapy; and 5). Special exercises. Fifty % of breech fetuses at 34 weeks will turn by themselves to head down by 38 weeks. Therefore, to be considered effective, a technique for turning breech must turn the baby and keep it turned more than 50% of the time. Only ECV with an experienced practitioner has been documented to have a greater than 50% success rate at 37 weeks; in 95% of cases the head stays down. Most women experience the fetus turning by hand as quick but very painful. "Unstable lie" is sometimes used as a baseless excuse for inducing labor after the baby turns from breech to head down. (judyslome@hotmail.com).

  17. Vehicle Technologies' Fact of the Week 2012

    Energy Technology Data Exchange (ETDEWEB)

    Davis, Stacy Cagle [ORNL; Diegel, Susan W [ORNL; Moore, Sheila A [ORNL; Boundy, Robert Gary [ORNL

    2013-02-01

    Each week the U.S. Department of Energy s Vehicle Technology Office (VTO) posts a Fact of the Week on their website: http://www1.eere.energy.gov/vehiclesandfuels/ . These Facts provide statistical information, usually in the form of charts and tables, on vehicle sales, fuel economy, gasoline prices, and other transportation-related trends. Each Fact is a stand-alone page that includes a graph, text explaining the significance of the data, the supporting information on which the graph was based, and the source of the data. A link to the current week s Fact is available on the VTO homepage, but older Facts are archived and still available at: http://www1.eere.energy.gov/vehiclesandfuels/facts/. This report is a compilation of the Facts that were posted during calendar year 2012. The Facts were written and prepared by staff in Oak Ridge National Laboratory's Center for Transportation Analysis.

  18. Hemophagocytic syndrome secondary to tuberculosis at 24-week gestation.

    Science.gov (United States)

    Fernández, Alexandra Arteaga; de Velasco Pérez, David Fernández; Fournier, M C Jiménez; Moreno Del Prado, J C; Torras, B Paraíso; Cañete Palomo, M L

    2017-01-01

    Hemophagocytic syndrome is a life-threatening disease characterized by the uncontrolled activation of macrophages, resulting in hemophagocytosis of blood cells in the bone marrow. A 20-year-old gravida at 23-week and 5-day gestation was admitted to hospital to evaluate fever up to 104°F of unknown origin, moderate cytopenia, and elevated levels of liver enzymes. Bone marrow biopsy confirmed hemophagocytic syndrome, and polymerase chain reaction came back positive for Mycobacterium tuberculosis. Supportive care and tuberculosis treatment resulted in clinical improvement. At 27 weeks and 5 days, premature rupture of the membranes occurred, and because of the high probability of reactivating the hemophagocytic syndrome, a cesarean section was performed at 29-week and 2-day gestation. Hemophagocytic syndrome is an uncommon disease which rarely appears during pregnancy. Early diagnosis and treatment can save both maternal and fetal lives.

  19. Hemophagocytic syndrome secondary to tuberculosis at 24-week gestation

    Directory of Open Access Journals (Sweden)

    Alexandra Arteaga Fernández

    2017-01-01

    Full Text Available Hemophagocytic syndrome is a life-threatening disease characterized by the uncontrolled activation of macrophages, resulting in hemophagocytosis of blood cells in the bone marrow. A 20-year-old gravida at 23-week and 5-day gestation was admitted to hospital to evaluate fever up to 104°F of unknown origin, moderate cytopenia, and elevated levels of liver enzymes. Bone marrow biopsy confirmed hemophagocytic syndrome, and polymerase chain reaction came back positive for Mycobacterium tuberculosis. Supportive care and tuberculosis treatment resulted in clinical improvement. At 27 weeks and 5 days, premature rupture of the membranes occurred, and because of the high probability of reactivating the hemophagocytic syndrome, a cesarean section was performed at 29-week and 2-day gestation. Hemophagocytic syndrome is an uncommon disease which rarely appears during pregnancy. Early diagnosis and treatment can save both maternal and fetal lives.

  20. Short-Term Market Risks Implied by Weekly Options

    DEFF Research Database (Denmark)

    Andersen, Torben Gustav; Fusari, Nicola; Todorov, Viktor

    a direct way to study volatility and jump risks. Unlike longer-dated options, they are largely insensitive to the risk of intertemporal shifts in the economic environment. Adopting a novel semi-nonparametric approach, we uncover variation in the negative jump tail risk which is not spanned by market......We study short-term market risks implied by weekly S&P 500 index options. The introduction of weekly options has dramatically shifted the maturity profile of traded options over the last five years, with a substantial proportion now having expiry within one week. Such short-dated options provide......" by the level of market volatility and elude standard asset pricing models....

  1. Use of magnesium sulfate before 32 weeks of gestation

    DEFF Research Database (Denmark)

    Wolf, H. T.; Weber, T.; Piedvache, A.

    2017-01-01

    Objectives: The use of magnesium sulfate (MgSO4) in European obstetric units is unknown. We aimed to describe reported policies and actual use of MgSO4 in women delivering before 32 weeks of gestation by indication. Methods: We used data from the European Perinatal Intensive Care in Europe (EPICE......) population-based cohort study of births before 32 weeks of gestation in 19 regions in 11 European countries. Data were collected from April 2011 to September 2012 from medical records and questionnaires. The study population comprised 720 women with severe preeclampsia, eclampsia or HELLP and 3658 without...... preeclampsia delivering from 24 to 31 weeks of gestation in 119 maternity units with 20 or more very preterm deliveries per year. Results: Among women with severe pre-eclampsia, eclampsia or HELLP, 255 (35.4%) received MgSO4 before delivery. 41% of units reported use of MgSO4 whenever possible for pre...

  2. Safety and convenience of once-weekly somapacitan in adult GH deficiency: a 26-week randomized, controlled trial.

    Science.gov (United States)

    Johannsson, Gudmundur; Feldt-Rasmussen, Ulla; Håkonsson, Ida Holme; Biering, Henrik; Rodien, Patrice; Tahara, Shigeyuki; Toogood, Andrew; Rasmussen, Michael Højby

    2018-05-01

    Somapacitan is a reversible albumin-binding growth hormone (GH) derivative, developed for once-weekly administration. This study aimed to evaluate the safety of once-weekly somapacitan vs once-daily Norditropin ® . Local tolerability and treatment satisfaction were also assessed. 26-week randomized, controlled phase 3 safety and tolerability trial in six countries (Nbib2382939). Male or female patients aged 18-79 years with adult GH deficiency (AGHD), treated with once-daily GH for ≥6 months, were randomized to once-weekly somapacitan ( n  = 61) or once-daily Norditropin ( n  = 31) administered subcutaneously by pen. Both treatments were dose titrated for 8 weeks to achieve insulin-like growth factor I (IGF-I) standard deviation score (SDS) levels within the normal range, and then administered at a fixed dose. Outcome measures were adverse events (AEs), including injection site reactions; occurrence of anti-somapacitan/anti-GH antibodies and change in treatment satisfaction, assessed using the Treatment Satisfaction Questionnaire for Medication-9 (TSQM-9). Mean IGF-I SDS remained between 0 and 2 SDS throughout the trial in both groups. AEs were mostly mild or moderate and transient in nature. The most common AEs were nasopharyngitis, headache and fatigue in both groups. More than 1500 somapacitan injections were administered and no clinically significant injection site reactions were reported. No anti-somapacitan or anti-GH antibodies were detected. The TSQM-9 score for convenience increased significantly more with somapacitan vs Norditropin ( P  = 0.0171). In this 26-week trial in patients with AGHD, somapacitan was well tolerated and no safety issues were identified. Once-weekly somapacitan was reported to be more convenient than once-daily Norditropin. © 2018 The authors.

  3. Early elective cesarean delivery before 36 weeks vs late spontaneous delivery in infants with gastroschisis.

    Science.gov (United States)

    Hadidi, Ahmed; Subotic, Ulrike; Goeppl, Maximilian; Waag, Karl-L

    2008-07-01

    The aim of this study is to assess the value of early elective cesarean delivery for patients with gastroschisis in comparison with late spontaneous delivery. Analysis of infants with gastroschisis admitted between 1986 and 2006 at a tertiary care center was performed. The findings were analyzed statistically. Eighty-six patients were involved in the study. This included 15 patients who underwent emergency cesarean delivery (EM CD group) because of fetal distress and/or bowel ischemia. The remaining 71 patients born electively were stratified into 4 groups. The early elective cesarean delivery (ECD) group included 23 patients born by ECD before 36 weeks; late vaginal delivery (LVD) group included 23 patients who had LVD after 36 weeks; 24 patients had LCD after 36 weeks because of delayed diagnosis that resulted in late referral; and 1 patient had early spontaneous vaginal delivery (EVD group) before 36 weeks. The mean time to start oral feeding, incidence of complications, and primary closure were significantly better in the ECD group than in the LVD group. The duration of ventilation and the length of stay were shorter in ECD group, but the difference was not statistically significant. Elective cesarean delivery before 36 weeks allows earlier enteral feeding and is associated with less complications and higher incidence of primary closure (statistically significant).

  4. Effect of 8 Weeks Soccer Training on Health and Physical Performance in Untrained Women.

    Science.gov (United States)

    Ortiz, Jaelson G; da Silva, Juliano F; Carminatti, Lorival J; Guglielmo, Luiz G A; Diefenthaeler, Fernando

    2018-03-01

    This study aims to analyze the physiological, neuromuscular, and biochemical responses in untrained women after eight weeks of regular participation in small-sided soccer games compared to aerobic training. Twenty-seven healthy untrained women were divided into two groups [soccer group (SG = 17) and running group (RG = 10)]. Both groups trained three times per week for eight weeks. The variables measured in this study were maximal oxygen uptake (VO 2 max), relative velocity at VO 2 max (vVO 2 max), peak velocity, relative intensity at lactate threshold (vLT), relative intensity at onset of blood lactate accumulation (vOBLA), peak force, total cholesterol, HDL, LDL, triglycerides, and cholesterol ratio (LDL/HDL). VO 2 max, vLT, and vOBLA increased significantly in both groups (12.8 and 16.7%, 11.1 and 15.3%, 11.6 and 19.8%, in SG and RG respectively). However, knee extensors peak isometric strength and triglyceride levels, total cholesterol, LDL, and HDL did not differ after eight weeks of training in both groups. On the other hand, the LDL/HDL ratio significantly reduced in both groups. In conclusion, eight weeks of regular participation in small-sided soccer games was sufficient to increase aerobic performance and promote health benefits related to similar aerobic training in untrained adult women.

  5. Effect of 8 Weeks Soccer Training on Health and Physical Performance in Untrained Women

    Directory of Open Access Journals (Sweden)

    Jaelson G. Ortiz, Juliano F. da Silva, Lorival J. Carminatti, Luiz G.A. Guglielmo, Fernando Diefenthaeler

    2018-03-01

    Full Text Available This study aims to analyze the physiological, neuromuscular, and biochemical responses in untrained women after eight weeks of regular participation in small-sided soccer games compared to aerobic training. Twenty-seven healthy untrained women were divided into two groups [soccer group (SG = 17 and running group (RG = 10]. Both groups trained three times per week for eight weeks. The variables measured in this study were maximal oxygen uptake (VO2max, relative velocity at VO2max (vVO2max, peak velocity, relative intensity at lactate threshold (vLT, relative intensity at onset of blood lactate accumulation (vOBLA, peak force, total cholesterol, HDL, LDL, triglycerides, and cholesterol ratio (LDL/HDL. VO2max, vLT, and vOBLA increased significantly in both groups (12.8 and 16.7%, 11.1 and 15.3%, 11.6 and 19.8%, in SG and RG respectively. However, knee extensors peak isometric strength and triglyceride levels, total cholesterol, LDL, and HDL did not differ after eight weeks of training in both groups. On the other hand, the LDL/HDL ratio significantly reduced in both groups. In conclusion, eight weeks of regular participation in small-sided soccer games was sufficient to increase aerobic performance and promote health benefits related to similar aerobic training in untrained adult women.

  6. Epo's Chronicles: A Weekly Webcomic That Teaches Space Science

    Science.gov (United States)

    Cominsky, Lynn R.; Prasad, K.; Simonnet, A.; John, K.; McLin, K.; Hill, L.

    2009-01-01

    Sonoma State University Education and Public Outreach presents Epo's Chronicles: a weekly web comic about Epo, a sentient spaceship/observatory and its humanoid companion, Alkina. Follow the adventures of Epo and Alkina as they explore the Universe and try to discover their origins. The comic employs a fictional story line incorporating both recent and classic scientific discoveries from NASA missions while educating the young and the young at heart in a creative and engaging way. Each weekly "eposode” is translated into French, Italian and Spanish, and is accompanied by supporting information including glossary entries, multi-media clips, and links to additional resources. Visit Epo's Chronicles at: http://eposchronicles.com

  7. Publication of a double Weekly Bulletin over Easter

    CERN Multimedia

    2003-01-01

    During the Easter period, the weeks of 21 and 28 April, there will be only one issue of the Weekly Bulletin (n°17-18/2003). Items for publication in this double issue should reach the Publication section or the Staff Association, as appropriate, before midday on Tuesday 15 April. There will therefore be no Bulletin distribution on Friday 25 April. Announcements for publication in the next issue (n°19/2003) should be sent on Tuesday 29 April by noon. Publications Section/ETT Tel. 79971

  8. Pregnancy week by week

    Science.gov (United States)

    ... Careers Archives Health Topics Pregnancy Before or between pregnancies Nutrition, weight & fitness Prenatal care Is it safe? Labor & ... Report Cards Careers Archives Pregnancy Before or between pregnancies Nutrition, weight & fitness Prenatal care Is it safe? Labor & ...

  9. 29 CFR 780.316 - Thirteen week provision.

    Science.gov (United States)

    2010-07-01

    ... consisting of seven consecutive 24-hour periods during which the employee worked at least 1 “man-day.” Section 3(u) of the Act defines a man-day as “any day during which an employee performs any agricultural... 13(a)(6)(C) (as well as section 3(e)(2)) comports with the traditional definition of week used in...

  10. 77 FR 16645 - National Poison Prevention Week, 2012

    Science.gov (United States)

    2012-03-21

    ... Russian Federation on the Measures for the Further Reduction and Limitation of Strategic Offensive Arms... learning more about how to prevent and respond to poison emergencies. Though we have dramatically reduced... information 24 hours a day, seven days a week at 1-800-222-1222. To encourage Americans to learn more about...

  11. Phacomatosis cesioflammea in a 5-week-old infant

    Directory of Open Access Journals (Sweden)

    Khushboo Gupta

    2016-01-01

    Full Text Available A 5-week-old male infant presented with extensive lesions of nevus flammeus and Mongolian spots affecting the face, trunk, buttocks and extremities. In addition, the child had ocular melanosis and a café-au-lait spot on the trunk. The case is being reported on account of its rarity.

  12. Changes in morphology and strength following an eight week ...

    African Journals Online (AJOL)

    The purpose of the current investigation was to determine the impact of eight weeks of progressive resistance exercise on strength and morphology of previously sedentary, healthy, post-menopausal women. Six women were recruited from the Grahamstown community in the Eastern Cape, South Africa. Recruits were ...

  13. Prediction of Success of External Cephalic Version after 36 Weeks

    NARCIS (Netherlands)

    Kok, Marjolein; van der Steeg, Jan Willem; van der Post, Joris A. M.; Mol, Ben W. J.

    2011-01-01

    We aimed to develop a predictive model for the chance of a successful external cephalic version (ECV). We performed a prospective cohort study of women with a singleton fetus in breech presentation with a gestational age of 36 weeks or more. Data on parity, maternal age, body mass index, ethnicity,

  14. 76 FR 12817 - National Consumer Protection Week, 2011

    Science.gov (United States)

    2011-03-09

    ..., from buying a home or car to paying off a loan or using a credit card. Consumer education is vital to... Week has encouraged Americans to make better-informed decisions about saving, buying, borrowing, and... information, families can both strengthen the economy and protect themselves from fraudulent behavior. For...

  15. The Learning Design Studio in a 5-weeks MOOC format

    NARCIS (Netherlands)

    Garreta-Domingo, Muriel; Hernández-Leo, Davinia; Mor, Yishay; Sloep, Peter

    2018-01-01

    The present paper reports on a Massive Open Online Courses (MOOCs) for teacher professional development that uses the Learning Design Studio methodology as a pedagogical framework. It explains the training activities and supporting technologies used and discusses the findings obtained weekly from

  16. 75 FR 58283 - National Hispanic-Serving Institutions Week, 2010

    Science.gov (United States)

    2010-09-23

    ... National Hispanic-Serving Institutions Week, 2010 By the President of the United States of America A... compete and thrive. Hispanic-Serving Institutions (HSIs) are key members of our higher education system... prosperous tomorrow for our Nation. NOW, THEREFORE, I, BARACK OBAMA, President of the United States of...

  17. 78 FR 62957 - National Forest Products Week, 2013

    Science.gov (United States)

    2013-10-23

    ... Public Law 86-753 (36 U.S.C. 123), as amended, has designated the week beginning on the third Sunday in...- eighth. (Presidential Sig.) [FR Doc. 2013-24990 Filed 10-22-13; 8:45 am] Billing code 3295-F4 ...

  18. Management of premature rupture of the membranes after 34 weeks ...

    African Journals Online (AJOL)

    Objective. To determine the optimal way to manage patients with premature rupture of the membranes after 34 weeks' gestation. Design. A prospective, randomised controlled trial comparing immediate induction and delayed induction after 24 • 48 hours. Setting. Tygerberg Hospital, Gape Town. Participants. Seventy ...

  19. 75 FR 27917 - Emergency Medical Services Week, 2010

    Science.gov (United States)

    2010-05-18

    ... enhancing our country's preparedness and resilience. During Emergency Medical Services Week, we recommit to... physicians. From rural regions of our Nation to our busiest urban centers, EMS teams provide access to... to arrive at the scene of a crisis. These heroic professionals, volunteers, and citizens form a...

  20. Elementary computer physics, a concentrated one-week course

    DEFF Research Database (Denmark)

    Christiansen, Gunnar Dan

    1978-01-01

    A concentrated one-week course (8 hours per day in 5 days) in elementary computer physics for students in their freshman university year is described. The aim of the course is to remove the constraints on traditional physics courses imposed by the necessity of only dealing with problems that have...... fields, and a lunar space vehicle are used as examples....

  1. Strengths use and work engagement : A weekly diary study

    NARCIS (Netherlands)

    van Woerkom, M.; Oerlemans, W.; Bakker, A.B.

    2016-01-01

    The present study among 65 civil engineers investigates the impact of organizational support for strengths use on weekly work engagement and proactive behaviour. Positive psychology postulates that strengths use makes people feel authentic and efficacious. We argue that employees use these positive

  2. BusinessWeek : meie valikuks on Google / Tarvo Vaarmets

    Index Scriptorium Estoniae

    Vaarmets, Tarvo

    2007-01-01

    Ajakiri BusinessWeek järjestas viimase kolme aasta tulemuste põhjal Standard & Poor's 500 indeksi koosseisu kuuluvad parimad ettevõtted. Tabel: Ettevõtete edetabel. Vt. samas: Google kroonib edetabelit; Sunoco; Colgate-Palmolive; Avon Products

  3. 77 FR 31149 - National Small Business Week, 2012

    Science.gov (United States)

    2012-05-24

    ... Small Business Week, 2012 By the President of the United States of America A Proclamation For centuries..., and we renew our promise to help their businesses grow, hire, and succeed. Because small businesses... workers and our businesses. Since I took office, we have repeatedly cut taxes for small businesses and...

  4. Beyond Therapy Dogs: Coordinating Large-Scale Finals Week Activities

    Science.gov (United States)

    Flynn, Holly

    2017-01-01

    Finals week activities have become increasingly popular in academic libraries in the last few years, but what is a library to do when it is not allowed to have therapy dogs? This column examines a progression of increasingly popular activities at Michigan State University Libraries. Included is an assessment of what makes them popular, our…

  5. Daily versus weekly iron supplementation and prevention of iron ...

    African Journals Online (AJOL)

    Objective: To demonstrate the effectiveness and social feasibility of weekly versus daily iron supplementation in preventing and treating iron deficiency anaemia among anaemic mothers. Design: A longitudinal in nature. Setting: Seven urban slum communities in Teklehaimanot Wereda, Addis Ababa, Ethiopia. Subjects: ...

  6. 75 FR 24367 - National Charter Schools Week, 2010

    Science.gov (United States)

    2010-05-05

    ... American spirit of limitless possibility to the next generation. NOW, THEREFORE, I, BARACK OBAMA, President... of a new age. My Administration is committed to helping schools prepare the next generation of... Charter Schools Week, 2010 By the President of the United States of America A Proclamation Our Nation's...

  7. Science Weekly for January 2: a preview of 2008

    CERN Multimedia

    2008-01-01

    Welcome to the first Science Weekly of 2008. Alok Jha and the team are on hand to gaze into their quasi-mystical balls and speculate on what will be the biggest scientific happenings over the next 12 months Ian Sample explains the intricacies of the Large Hadron Collider (LHC)

  8. 20 CFR 615.6 - Extended Benefits; weekly amount.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Extended Benefits; weekly amount. 615.6 Section 615.6 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR EXTENDED... compensation payable during such benefit year. (2) If the method in paragraph (a)(1)(iii) of this section is...

  9. 76 FR 25525 - National Charter Schools Week, 2011

    Science.gov (United States)

    2011-05-05

    ... excellence by harnessing the power of new ideas, ground-breaking strategies, and the collective involvement of students, parents, teachers, and administrators. During National Charter Schools Week, we... with other public schools on how to organize teaching and learning and enhance curricula. As part of...

  10. Special Relativity in Week One: 4) Lack of Simultaneity

    Science.gov (United States)

    Huggins, Elisha

    2011-01-01

    This is our final article on teaching special relativity in the first week of an introductory physics course. One of the profound changes in our view of the world was Einstein's discovery of the lack of simultaneity. He illustrated this result with a thought experiment in which we observe a railroad car passing by us. We see the two ends of the…

  11. Hoogsalt moodne Tallinn Fashion Week / Jaanika Terasmaa : intervjueerinud Annely Martin

    Index Scriptorium Estoniae

    Terasmaa, Jaanika

    2010-01-01

    Tallinn Fashion Week kestab 7. novembrini. Üks moenädala korraldajaid Jaanika Terasmaa, sellest, mida moenädal pakub tavainimesele ja kui oluline on selline ettevõtmine moeloojatele, moenädala eesmärgist

  12. Four-week oral toxicity study with erythritol in rats

    NARCIS (Netherlands)

    Til, H.P.; Modderman, J.

    1996-01-01

    Erythritol was orally administered to Wistar rats at dietary levels of 0, 5, and 10% for 4 weeks. Soft stools and diarrhea were observed in male and female animals of the 10% group and in female animals of the 5% group. These symptoms disappeared during the course of the study. Mean body weights of

  13. The European Microwave Week 2008 and its Microwave Conferences

    NARCIS (Netherlands)

    Hoogeboom, P.; Van Vliet, F.

    2009-01-01

    Under the auspices of the European Microwave Association (EuMA) the 11th annual European Microwave Week was organized in the Amsterdam RAI Congress Centre, The Netherlands, 27-31 October 2008. This major event consisted this year of five conferences, an exhibition, and various side events. The 38th

  14. Effects of 16 weeks of aerobic, resistance and combination exercise ...

    African Journals Online (AJOL)

    Effects of 16 weeks of aerobic, resistance and combination exercise programmes on smoking. ... African Journal for Physical Activity and Health Sciences ... Abstract. Previous research on the cessation of smoking and the prevention of smoking recidivism using exercise training has mainly focused on aerobic training (AER).

  15. The Rewards of a Four-Day School Week.

    Science.gov (United States)

    Featherstone, Helen

    1991-01-01

    Instead of cutting art, music, or physical education, the usual victims of budgetary shortfalls, the principal and staff of a New Hampshire elementary school balanced their 1981 budget by adopting a "temporary" Monday-Thursday schedule that remains operational today. The four-day week has brought a dramatic drop in teacher absenteeism…

  16. Ruptured rudimentary horn at 22 weeks | Dhar | Nigerian Medical ...

    African Journals Online (AJOL)

    Rudimentary horn is a developmental anomaly of the uterus. Pregnancy in a noncommunicating rudimentary horn is very difficult to diagnose before it ruptures. A case of undiagnosed rudimentary horn pregnancy at 22 weeks presented to Nizwa regional referral hospital in shock with features of acute abdomen. Chances of ...

  17. 76 FR 65097 - National Forest Products Week, 2011

    Science.gov (United States)

    2011-10-20

    ... National Forest Products Week, 2011 By the President of the United States of America A Proclamation America... access clean water and air, drive discovery as natural laboratories, and make our communities more... and preservation of these national treasures. Through the America's Great Outdoors Initiative, my...

  18. Science weekly for January 2: a preview of 2008

    CERN Multimedia

    2008-01-01

    The Science Weekly team look ahead to the scientific year of 2008. Will the LHC work? What breakthroughs will there be in the field of synthetic biology? What will happen with climate change policy? Plus, a new song by our troubadour Jonny Berliner (1/2 page)

  19. 76 FR 58711 - National Farm Safety and Health Week, 2011

    Science.gov (United States)

    2011-09-21

    ... National Farm Safety and Health Week, 2011 By the President of the United States of America A Proclamation... and processing facilities. Physically demanding and all-encompassing, farm work requires the... worked to create new markets for these products, and to provide assistance to farms, supporting jobs...

  20. Colorado's Alternative School Calendar Program and the Four Day Week.

    Science.gov (United States)

    Brubacher, Roy G.; Stiverson, C. L.

    Taking advantage of legislation permitting modified school calendars, the four-day work week has been implemented by 23 small, rural Colorado school districts representing 5,200 children. Thirteen districts implemented the four-day program in the 1980-81 school year. Ten additional districts applied as first year pilot programs in the 1981-82…

  1. Substrate utilization during the first weeks of life

    NARCIS (Netherlands)

    Sauer, P. J.; Carnielli, V. P.; Sulkers, E. J.; van Goudoever, J. B.

    1994-01-01

    It is assumed that substrate utilization changes markedly around birth, from mainly glucose utilization before, to glucose/fat utilization after birth. We studied substrate oxidation and turnover in preterm infants on the first day and during the first weeks of life. We found that only part of the

  2. 75 FR 63689 - National School Lunch Week, 2010

    Science.gov (United States)

    2010-10-15

    .... To foster school environments that encourage physical activity and nourishing diets, ``Let's Move... for nutritional quality in school food, participation in meal programs, physical activity, and... National School Lunch Week, we recognize the vital importance of this historic program, and we recommit to...

  3. Special Relativity in Week One: 2) All Clocks Run Slow

    Science.gov (United States)

    Huggins, Elisha

    2011-01-01

    In our initial article on teaching special relativity in the first week of an introductory physics course, we used the principle of relativity and Maxwell's theory of light to derive Einstein's second postulate (that the speed of light is the same to all observers). In this paper we study thought experiments involving a light pulse clock moving…

  4. Impact of 12 weeks of resistance training on physical and functional fitness in elderly women

    Directory of Open Access Journals (Sweden)

    Aline Mendes Gerage

    2013-03-01

    Full Text Available DOI: http://dx.doi.org/10.5007/1980-0037.2013v15n2p145 The objective of the study was to analyze the impact of 12 weeks of resistance training (RT on physical functional fitness in elderly women. Fifty-one elderly women (66.1±4.4 years, apparently healthy, insufficiently active, and without prior experience in RT were randomly assigned into two groups: Training Group (TG = 24 and Control Group (CG = 27. The TG was submitted to a standardized RT program composed of eight exercises, performed in two sets of 10 to 15 repetitions, three times a week, and the CG was submitted to a 12 week stretching exercise program composed by two sessions per week of 30 minutes each. Their physical and functional fitness level was analyzed before and after the intervention period by motor testing to assess Right and Left Upper Limb Endurance (RULE, LULE, Lower Limb Endurance (LLE, Flexibility (FLEX, Manual Skills (MS, Ability to Put on Socks (APS, and Coordination (COORD. The TG had improved performance in LLE (+13.8%, RULE (+24.3%, LULE (+22.9%, and MS (- 0.9 s, whereas the CG improved performance in RULE (+13.9% and LULE (+14.1%, but had increased time in COORD by (+1.5 s, and these were the only tests showing significant interactions of group vs. time (p<0.05. The results suggest that 12 weeks of RT seem to be sufficient to induce positive changes on physical and functional fitness of healthy and previously untrained elderly women.

  5. SU-F-T-96: A New Paradigm of Weekly Chart Checking for Radiation Therapy Clinics

    International Nuclear Information System (INIS)

    Tan, J; Pompos, A; Jiang, S; Yan, Y

    2016-01-01

    Purpose: To put forth an innovative clinical paradigm for weekly chart checking so that treatment status is periodically checked accurately and efficiently. This study also aims to help optimize the chart checking clinical workflow in a busy radiation therapy clinic. Methods: It is mandated by the Texas Administrative code to check patient charts of radiation therapy once a week or every five fractions, however it varies drastically among institutions in terms of when and how it is done. Some do it every day, but a lot of efforts are wasted on opening ineligible charts; some do it on a fixed day but the distribution of intervals between subsequent checks is not optimal. To establish an optimal chart checking procedure, a new paradigm was developed to achieve 1) charts are checked more accurately and more efficiently; 2) charts are checked on optimal days without any miss; 3) workload is evened out throughout a week when multiple physicists are involved. All active charts will be accessed by querying the R&V system. Priority is assigned to each chart based on the number of days before the next due date followed by sorting and workload distribution steps. New charts are also taken into account when distributing the workload so it is reasonably even throughout the week. Results: Our clinical workflow became more streamlined and smooth. In addition, charts get checked in a more timely fashion so that errors would get caught earlier should they occur. Conclusion: We developed a new weekly chart checking diagram. It helps physicists check charts in a timely manner, saves their time in busy clinics, and consequently reduces possible errors.

  6. SU-F-T-96: A New Paradigm of Weekly Chart Checking for Radiation Therapy Clinics

    Energy Technology Data Exchange (ETDEWEB)

    Tan, J; Pompos, A; Jiang, S; Yan, Y [UT Southwestern Medical Center, Dallas, TX (United States)

    2016-06-15

    Purpose: To put forth an innovative clinical paradigm for weekly chart checking so that treatment status is periodically checked accurately and efficiently. This study also aims to help optimize the chart checking clinical workflow in a busy radiation therapy clinic. Methods: It is mandated by the Texas Administrative code to check patient charts of radiation therapy once a week or every five fractions, however it varies drastically among institutions in terms of when and how it is done. Some do it every day, but a lot of efforts are wasted on opening ineligible charts; some do it on a fixed day but the distribution of intervals between subsequent checks is not optimal. To establish an optimal chart checking procedure, a new paradigm was developed to achieve 1) charts are checked more accurately and more efficiently; 2) charts are checked on optimal days without any miss; 3) workload is evened out throughout a week when multiple physicists are involved. All active charts will be accessed by querying the R&V system. Priority is assigned to each chart based on the number of days before the next due date followed by sorting and workload distribution steps. New charts are also taken into account when distributing the workload so it is reasonably even throughout the week. Results: Our clinical workflow became more streamlined and smooth. In addition, charts get checked in a more timely fashion so that errors would get caught earlier should they occur. Conclusion: We developed a new weekly chart checking diagram. It helps physicists check charts in a timely manner, saves their time in busy clinics, and consequently reduces possible errors.

  7. Changing Survival Rate of Infants Born Before 26 Gestational Weeks

    Science.gov (United States)

    Rahman, Asad; Abdellatif, Mohamed; Sharef, Sharef W.; Fazalullah, Muhammad; Al-Senaidi, Khalfan; Khan, Ashfaq A.; Ahmad, Masood; Kripail, Mathew; Abuanza, Mazen; Bataclan, Flordeliza

    2015-01-01

    Objectives: This study aimed to evaluate the changing survival rate and morbidities among infants born before 26 gestational weeks at the Sultan Qaboos University Hospital (SQUH) in Muscat, Oman. Methods: This retrospective study assessed the mortality and morbidities of all premature infants born alive at 23–26 gestational weeks at SQUH between June 2006 and May 2013. Infants referred to SQUH within 72 hours of birth during this period were also included. Electronic records were reviewed for gestational age, gender, birth weight, maternal age, mode and place of delivery, antenatal steroid administration, morbidity and outcome. The survival rate was calculated and findings were then compared with those of a previous study conducted in the same hospital from 1991 to 1998. Rates of major morbidities were also calculated. Results: A total of 81 infants between 23–26 gestational weeks were admitted to the neonatal unit during the study period. Of these, 58.0% were male and 42.0% were female. Median gestational age was 25 weeks and mean birth weight was 770 ± 150 g. Of the 81 infants, 49 survived. The overall survival rate was 60.5% compared to 41% reported in the previous study. Respiratory distress syndrome (100.0%), retinopathy of prematurity (51.9%), bronchopulmonary dysplasia (34.6%), intraventricular haemorrhage (30.9%) and patent ductus arteriosus (28.4%) were the most common morbidities. Conclusion: The overall survival rate of infants between 23–26 gestational weeks during the study period had significantly improved in comparison to that found at the same hospital from 1991 to 1998. There is a need for the long-term neurodevelopmental follow-up of premature infants. PMID:26357555

  8. Short, frequent, 5-days-per-week, in-center hemodialysis versus 3-days-per week treatment: a randomized crossover pilot trial through the Midwest Pediatric Nephrology Consortium.

    Science.gov (United States)

    Laskin, Benjamin L; Huang, Guixia; King, Eileen; Geary, Denis F; Licht, Christoph; Metlay, Joshua P; Furth, Susan L; Kimball, Tom; Mitsnefes, Mark

    2017-08-01

    No controlled trials in children with end-stage kidney disease have assessed the benefits of more frequently administered hemodialysis (HD). We conducted a multicenter, crossover pilot trial to determine if short, more frequent (5 days per week) in-center HD was feasible and associated with improvements in blood pressure compared with three conventional HD treatments per week. Because adult studies have not controlled for the weekly duration of dialysis, we fixed the total treatment time at 12 h a week of dialysis during two 3-month study periods; only frequency varied from 5 to 3 days per week between study periods. Eight children (median age 16.7 years) consented at three children's hospitals. The prespecified primary composite outcome was a sustained 10% decrease in systolic blood pressure and/or a decrease in antihypertensive medications relative to each study period's baseline. Among the six patients completing both study periods, five (83.3%) experienced the primary outcome during HD performed 5 days per week but not 3 days per week; one of the six (16.7%) achieved that outcome during 3-day but not 5-day (p = 0.22) per week HD. During 5-day HD, all patients had significantly more treatments during which their pre-HD systolic (p = 0.01) or diastolic (p = 0.01) blood pressure was 10% lower than baseline. We observed that more frequent HD sessions per week was feasible and associated with improved blood pressure control, but barriers to changing thrice-weekly standard of care include financial reimbursement and the time demands associated with more frequent treatments.

  9. Fetal movement detection: comparison of the Toitu actograph with ultrasound from 20 weeks gestation.

    Science.gov (United States)

    DiPietro, J A; Costigan, K A; Pressman, E K

    1999-01-01

    This study evaluates the validity of Doppler-detected fetal movement by a commercially available monitor and investigates whether characteristics of maternal body habitus and the intrauterine environment affect its performance. Fetal movement was evaluated in normal pregnancies using both ultrasound visualization and a fetal actocardiograph (Toitu MT320; Tofa Medical Inc., Malvern, PA). Data were collected for 32 min on 34 fetuses stratified by gestational age (20-25 weeks; 28-32 weeks; 35-39 weeks). Fetal and maternal characteristics were recorded. Comparisons between ultrasound-detected trunk and limb movements and actograph records were conducted based both on 10-s time intervals and on detection of individual movements. Time-based comparisons indicated agreement between ultrasound and actograph 94.7% of the time; this association rose to 98% when movements of less than 1 s duration were excluded. Individual movements observed on ultrasound were detected by the actograph 91% of the time, and 97% of the time when brief, isolated movements were excluded. The overall kappa value for agreement was 0.88. The actograph was reliable in detecting periods of quiescence as well as activity. These findings did not vary by gestational age. The number of movements detected by the actograph, but not the single-transducer ultrasound, significantly increased over gestation. Maternal age, parity, weight, height, or body mass index were not consistently associated with actograph validity. Characteristics of the uterine environment, including placenta location, fetal presentation, and amniotic fluid volume also did not affect results. The Toitu actograph accurately detects fetal movement and quiescence from as early as 20 weeks gestation and has utility in both clinical and research settings. Actographs are most useful for providing objective and quantifiable measures of fetal activity level, including number and duration of movements, while visualization through ultrasound is

  10. Comparison of Dosage Requirement of Erythropoietin Stimulating Agent (ESA in Maintenance of Hemoglobin Concentration in patients undergoing twice weekly versus thrice weekly Hemodialysis in Pakistani Population

    Directory of Open Access Journals (Sweden)

    Osama Kunwer Naveed

    2018-03-01

    . First our study only looked at Hb levels, iron stores and dosages of ESA, while other factors like Parathyroid Hormone(PTH levels and Vitamin B12 were not considered that may have a role in anemia of chronic renal disease. In addition, it was a study limited to one center only and a multicenter trial should be taken to validate the results. We have reported one aspect of dialysis vintage i.e.  high ESA dosage requirement Conclusion: We found that patients undergoing hemodialysis three times a week require recommended dosage of ESA; however those undergoing hemodialysis less than three times a week require higher dosage of ESA to maintain Hb level. Here we report significant effect of hemodialysis on ESA dosage to maintain same level of Hb.

  11. Circadian Macronutrients Variations over the First 7 Weeks of Human Milk Feeding of Preterm Infants.

    Science.gov (United States)

    Moran-Lev, Hadar; Mimouni, Francis B; Ovental, Amit; Mangel, Laurence; Mandel, Dror; Lubetzky, Ronit

    2015-09-01

    Little is known about circadian variations of macronutrients content of expressed preterm human milk (HM). This study evaluated diurnal variations of macronutrients and energy content of preterm HM over the first 7 weeks of lactation and tested the hypothesis that values obtained during a morning sample are predictive of those obtained from an evening sample. Expressed HM was obtained from 32 mothers of preterm infants (26-33 weeks in gestational age), who routinely expressed all their milk every 3 hours from the beginning of the second to the seventh week after delivery. One aliquot was obtained from the first morning expression and the second from the evening expression. Energy and macronutrients contents were measured using an HM analyzer. Mean fat and energy contents of all samples obtained during the whole period were significantly higher in evening samples (p < 0.0001). There were no significant differences between morning and evening carbohydrates and protein contents. Concentrations of protein, carbohydrates, and fat from morning samples were predictive of evening concentrations to different extents (R(2) = 0.720, R(2) = 0.663, and R(2) = 0.20, respectively; p < 0.02). The predictability of evening values by morning values was not influenced by the week of lactation at sampling or by individual patients. In repeated-measures analysis of variance performed on 11 patients who completed the whole 7-week period, over time, there was a significant decrease in fat, energy, and protein contents, whereas carbohydrates content remained unchanged. Day-night differences remained significant only for fat content. Circadian variations in fat and energy concentrations of HM are consistent over the first 7 weeks of lactation. There are no consistent circadian variations in HM protein and carbohydrates. Over a given day, there are little variations in protein and carbohydrates content, but fat concentrations are more variable, and evening values are less well predicted by

  12. The Weekly Fab Five: Things You Should Do Every Week To Keep Your Computer Running in Tip-Top Shape.

    Science.gov (United States)

    Crispen, Patrick

    2001-01-01

    Describes five steps that school librarians should follow every week to keep their computers running at top efficiency. Explains how to update virus definitions; run Windows update; run ScanDisk to repair errors on the hard drive; run a disk defragmenter; and backup all data. (LRW)

  13. Study on Pb Content in 3 Week and 6 Week Old Kangkung (Ipomoea reptans Poir Planted in Pb containing Media

    Directory of Open Access Journals (Sweden)

    Poppy Hartatie Hardjo

    2005-11-01

    Full Text Available A study on the content of Pb in kangkung has been conducted. Land kangkung (Ipomoea reptans was used as the sample, and was planted in hydrophonic media, and watered with Multigrow Complete Plant Food (2000 mg/L and Pb solution (2 mg/L twice a day. Samples were taken based on the age (3 and 6 week old, and part of the plant (root and all parts without root. Inductively Coupled Plasma Spectrometer (ICPS Fison 3410+ was used to measure the Pb content. It was shown that in the plant the accumulation was mostly happened in the root. The 6 week-old plant contained Pb not just in the root (3.36 mg/kg sample but also in the other part of the plant (2.09 mg/kg sample and those were exceeded the maximum dietary allowance (2 mg/kg sample regulated by the Indonesian FDA; while in the 3 week-old plant the Pb content in the root was 1.86 mg/kg sample and in the other part of the plan was 1.13 mg/kg, which is not exceeded the dietary allowance. So it is advisable to harvest the kangkung vegetable at the most of 3 week-old.

  14. Efficacy and safety of once-weekly intravenous epoetin alfa in maintaining hemoglobin levels in hemodialysis patients.

    Science.gov (United States)

    Locatelli, Francesco; Villa, Giuseppe; Messa, Piergiorgio; Filippini, Armando; Cannella, Giuseppe; De Ferrari, Giacomo; Naso, Agostino; Rossi, Egidio; Formica, Marco; Lombardi, Luigi; Rotolo, Ugo; Conte, Feruccio

    2008-01-01

    Although an erythropoiesis-stimulating agent (ESA) is most frequently administered intravenously for treatment of anemia in patients with chronic kidney disease who are on dialysis, few studies have compared the efficacy of different intravenous (i.v.) dosing schedules. This multicenter, phase IIIb, open-label, controlled study randomized 289 stable hemodialysis patients to continue with conventional dosing of i.v. epoetin alfa or darbepoetin, or to switch to once-weekly i.v. epoetin alfa at the same cumulative weekly starting dose, to maintain hemoglobin levels at 11.0-13.0 g/dL, and within 1.0 g/dL of the baseline value. Hemoglobin levels and ESA doses were recorded every 4 weeks for 28 weeks. Hemoglobin levels fell significantly and ESA doses increased significantly between baseline and week 28 (mean of week 16-28 values) in the once-weekly epoetin alfa group, compared with the conventional treatment group (phemoglobin levels between the groups was 0.73 g/dL (greater than the threshold for therapeutic equivalence of 0.5 g/dL). The changes between groups from baseline was significant at all time points for hemoglobin levels (0.36, 0.46, 0.81, 0.87, 0.78, 0.62 and 0.49 g/dL) and from week 12 for ESA dose (718.5, 1,326.5, 1,732.0, 1,839.7 and 1,959.1 IU/week; p=0.005). Hemoglobin was maintained at the target level in 78% and 84% of patients on conventional dosing, and 67% and 64% of those on once-weekly epoetin alfa in the intention-to-treat (p=0.1) and per protocol (p=0.016) populations, respectively. This study did not show therapeutic equivalence of once-weekly i.v. epoetin alfa with conventional dosing regimens.

  15. SU-D-BRD-02: Auto Weekly - An Automated Online Weekly Chart Check System for Medical Physics

    International Nuclear Information System (INIS)

    Tan, J; Yan, Y; Hager, F; Gu, X; Jia, X; Pompos, A; Foster, R; Stojadinovic, S; Yang, M; Hrycushko, B; Folkerts, M; Zhao, B; Medin, P; Ding, C; Jiang, S

    2015-01-01

    Purpose: Radiation therapy has evolved to become not only more precise and potent, but also more complicated to monitor and deliver. More rigorous and comprehensive quality assurance is needed to safeguard ever advancing radiation therapy. ICRU standards dictate that an ever growing set of treatment parameters are manually checked weekly by medical physicists. This “weekly chart check” procedure is laborious and subject to human errors or other factors. A computer-assisted chart checking process will enable more complete and accurate human review of critical parameters, reduce the risk of medical errors, and improve the efficiency. Methods: We developed a web-based software system that enables a thorough weekly quality assurance checks. In the backend, the software retrieves all machine parameters from a Treatment Management System (TMS) and compares them against the corresponding ones from the treatment planning system. They are also checked for validity against preset rules. The results are displayed as a web page in the front-end for physicists to review. Then a summary report is generated and uploaded automatically to the TMS as a record for weekly chart checking. Results: The software system has been deployed on a web server in our department’s intranet, and has been tested thoroughly by our clinical physicists. A plan parameter would be highlighted when it is off the preset limit. The developed system has changed the way of checking charts with significantly improved accuracy, efficiency, and completeness. It has been shown to be robust, fast, and easy to use. Conclusion: A computer-assisted system has been developed for efficient, accurate, and comprehensive weekly chart checking. The system has been extensively validated and is being implemented for routine clinical use

  16. SU-D-BRD-02: Auto Weekly - An Automated Online Weekly Chart Check System for Medical Physics

    Energy Technology Data Exchange (ETDEWEB)

    Tan, J; Yan, Y; Hager, F; Gu, X; Jia, X; Pompos, A; Foster, R; Stojadinovic, S; Yang, M; Hrycushko, B; Folkerts, M; Zhao, B; Medin, P; Ding, C; Jiang, S [UT Southwestern Medical Center, Dallas, TX (United States)

    2015-06-15

    Purpose: Radiation therapy has evolved to become not only more precise and potent, but also more complicated to monitor and deliver. More rigorous and comprehensive quality assurance is needed to safeguard ever advancing radiation therapy. ICRU standards dictate that an ever growing set of treatment parameters are manually checked weekly by medical physicists. This “weekly chart check” procedure is laborious and subject to human errors or other factors. A computer-assisted chart checking process will enable more complete and accurate human review of critical parameters, reduce the risk of medical errors, and improve the efficiency. Methods: We developed a web-based software system that enables a thorough weekly quality assurance checks. In the backend, the software retrieves all machine parameters from a Treatment Management System (TMS) and compares them against the corresponding ones from the treatment planning system. They are also checked for validity against preset rules. The results are displayed as a web page in the front-end for physicists to review. Then a summary report is generated and uploaded automatically to the TMS as a record for weekly chart checking. Results: The software system has been deployed on a web server in our department’s intranet, and has been tested thoroughly by our clinical physicists. A plan parameter would be highlighted when it is off the preset limit. The developed system has changed the way of checking charts with significantly improved accuracy, efficiency, and completeness. It has been shown to be robust, fast, and easy to use. Conclusion: A computer-assisted system has been developed for efficient, accurate, and comprehensive weekly chart checking. The system has been extensively validated and is being implemented for routine clinical use.

  17. Perceptual statistical learning over one week in child speech production.

    Science.gov (United States)

    Richtsmeier, Peter T; Goffman, Lisa

    2017-07-01

    What cognitive mechanisms account for the trajectory of speech sound development, in particular, gradually increasing accuracy during childhood? An intriguing potential contributor is statistical learning, a type of learning that has been studied frequently in infant perception but less often in child speech production. To assess the relevance of statistical learning to developing speech accuracy, we carried out a statistical learning experiment with four- and five-year-olds in which statistical learning was examined over one week. Children were familiarized with and tested on word-medial consonant sequences in novel words. There was only modest evidence for statistical learning, primarily in the first few productions of the first session. This initial learning effect nevertheless aligns with previous statistical learning research. Furthermore, the overall learning effect was similar to an estimate of weekly accuracy growth based on normative studies. The results implicate other important factors in speech sound development, particularly learning via production. Copyright © 2017 Elsevier Inc. All rights reserved.

  18. Weekly changes of power supplier - consequences for the network owner

    International Nuclear Information System (INIS)

    Graabak, Ingeborg

    1997-01-01

    In Norway, it is expected that owners of electric distribution networks will be required to make it possible for the customers to change supplier each week. This report examines what consequences such a requirement will have for the network owners. An inquiry among nine network owners shows that at present changing supplier implies a great deal of manual work on the part of the network owner since many do not have computer based tools adapted to handle the situation. If the number of weekly changes of suppliers does not increase beyond a few percent of the network owner's total number of customers over 1 to 3 years, the network owner can cope with the situation. However, if for some reason the increase becomes larger, many network owners will have great problems because they lack the necessary computer tools. 1 table

  19. Body Stalk Anomaly in a 9-Week Pregnancy

    Directory of Open Access Journals (Sweden)

    Fabio E. Quijano

    2014-01-01

    Full Text Available Body stalk anomaly is a rare and severe malformation syndrome in which the exact pathophysiology and trigger factors are still unknown. This is a case of a 30-year-old patient who underwent ultrasound at 9 weeks of gestation. It revealed an abnormal location of the inferior body of the embryo in the coelomic space. The findings suggested a short umbilical cord syndrome. In order to confirm the diagnosis, the patient was scheduled for a second ultrasonography at 11 weeks of gestation. The obtained images, confirmed the location of the inferior body in the coelomic space with no visible bladder, absence of the right leg, severe abdominal wall defect, consistent with an omphalocele, and a short 5 mm umbilical cord. These last ultrasonographic findings were consistent with body stalk anomaly. Because of severe malformation incompatible with life, the patient was offered termination of pregnancy. Pathologic examination confirmed the suspected pathology of body stalk anomaly.

  20. The construction of the other in a Brazilian weekly magazine

    Directory of Open Access Journals (Sweden)

    José Luiz Aidar Prado

    2005-12-01

    Full Text Available Postmodern thought considers, in general, otherness as absolute. Bernstein (1991 denies such absoluteness, as there is always a possibility of failure in doing justice to the otherness; we should assume the responsibility of acknowledging the otherness of the Other. In this article I propose to examine the possibility of regarding the relationship between the reader and the media as ethical, that is, respecting otherness. To do so, we counterbalance the bernsteinian view with other stances, confronting communitarian authors and non-communitarian ones. What would be the meaning of the Reader’s unfaithfulness in terms of a reading and communication contract? We intend to answer such questions on the basis of a thematic and discursive examination of the Brazilian weekly magazine Veja (approximately one million issues weekly, particularly analyzing how otherness is constructed in the cover stories dealing with topics such as violence and punishment, wealth and poverty.

  1. Vehicle Technologies' Fact of the Week 2011

    Energy Technology Data Exchange (ETDEWEB)

    Davis, Stacy Cagle [ORNL; Diegel, Susan W [ORNL; Boundy, Robert Gary [ORNL

    2012-04-01

    Each week the U.S. Department of Energy s Vehicle Technology Program (VTP) posts a Fact of the Week on their website: http://www1.eere.energy.gov/vehiclesandfuels/. These Facts provide statistical information, usually in the form of charts and tables, on vehicle sales, fuel economy, gasoline prices, and other transportation-related trends. Each Fact is a stand-alone page that includes a graph, text explaining the significance of the data, the supporting information on which the graph was based, and the source of the data. A link to the current Fact is available Monday through Friday on the VTP homepage, but older Facts are archived and still available at: http://www1.eere.energy.gov/vehiclesandfuels/facts/. This report is a compilation of the Facts that were posted during calendar year 2011. The Facts were written and prepared by staff in Oak Ridge National Laboratory's Center for Transportation Analysis.

  2. Optimization of the weekly operation of a multipurpose hydroelectric development, including a pumped storage plant

    International Nuclear Information System (INIS)

    Popa, R; Popa, B; Popa, F; Zachia-Zlatea, D

    2010-01-01

    It is presented an optimization model based on genetic algorithms for the operation of a multipurpose hydroelectric power development consisting in a pumped storage plant (PSP) with weekly operation cycle. The lower reservoir of the PSP is supplied upstream from a peak hydropower plant (HPP) with a large reservoir and supplies the own HPP which provides the required discharges towards downstream. Under these conditions, the optimum operation of the assembly consisting in 3 reservoirs and hydropower plants becomes a difficult problem if there are considered the restrictions as regards: the gradients allowed for the reservoirs filling/emptying, compliance with of a long-term policy of the upper reservoir from the hydroelectric development and of the weekly cycle for the PSP upper reservoir, correspondence between the power output/consumption in the weekly load schedule, turning to account of the water resource at maximum overall efficiencies, etc. Maximization of the net energy value (generated minus consumed) was selected as performance function of the model, considering the differentiated price of the electric energy over the week (working or weekend days, peak, half-peak or base hours). The analysis time step was required to be of 3 hours, resulting a weekly horizon of 56 steps and 168 decision variables, respectively, for the 3 HPPs of the system. These were allowed to be the flows turbined at the HPP and the number of working hydrounits at PSP, on each time step. The numerical application has considered the guiding data of Fantanele-Tarnita-Lapustesti hydroelectric development. Results of various simulations carried out proved the qualities of the proposed optimization model, which will allow its use within a decisional support program for such a development.

  3. Effects of eight weeks of physical training on physical performance and heart rate variability in children

    Directory of Open Access Journals (Sweden)

    Kraama Liisa

    2017-12-01

    Full Text Available Study aim: Physically active adults have been shown to have higher heart rate variability (HRV than less active adults, but less is known about children in this regard. In adults, training-induced changes in physical performance have been shown to be related to increase in HRV, especially in its high frequency component (HF, which is a marker of parasympathetic activity. The purpose of this study was to examine whether 8 weeks of instructed physical training would improve physical performance and cardiac autonomic function (HRV in secondary school pupils and to examine the relationship between changes in physical performance and the function of the autonomic nervous system. Material and methods: The test group included 12 girls and 12 boys and the control group 7 girls and 7 boys. All the sub­jects were 13-15 years old. Physical training included warm up, circuit training, endurance training, stretching and relaxation 3 times a week for eight weeks. Endurance training intensity was 70-75% of maximal heart rate. Endurance, flexibility, speed and power were measured before and after training. The low frequency (LF and high frequency (HF components of HRV were recorded in supine rest and in standing conditions before and after the eight-week period. Results: Time to exhaustion in the endurance test increased in the test group (p < 0.001, flexibility and ball throwing improved in the test group (p < 0.05, while no changes were observed in the control group. No significant changes were observed in HRV in either group. Conclusions: In conclusion, eight weeks of physical training improves physical performance in children, but it might not affect autonomic cardiac function.

  4. Optimization of the weekly operation of a multipurpose hydroelectric development, including a pumped storage plant

    Energy Technology Data Exchange (ETDEWEB)

    Popa, R; Popa, B [Faculty of Power Engineering, University Politehnica of Bucharest, 313 Spl. Independentei, sect. 6, Bucharest, 060042 (Romania); Popa, F [Institute for Hydropower Studies and Design, 5-7 Vasile Lascar, sect. 2, Bucharest, 020491 (Romania); Zachia-Zlatea, D, E-mail: bogdan.popa@rosha.r [Hidroelectrica S.A., 3 Constantin Nacu, sect. 2, Bucharest, 020995 (Romania)

    2010-08-15

    It is presented an optimization model based on genetic algorithms for the operation of a multipurpose hydroelectric power development consisting in a pumped storage plant (PSP) with weekly operation cycle. The lower reservoir of the PSP is supplied upstream from a peak hydropower plant (HPP) with a large reservoir and supplies the own HPP which provides the required discharges towards downstream. Under these conditions, the optimum operation of the assembly consisting in 3 reservoirs and hydropower plants becomes a difficult problem if there are considered the restrictions as regards: the gradients allowed for the reservoirs filling/emptying, compliance with of a long-term policy of the upper reservoir from the hydroelectric development and of the weekly cycle for the PSP upper reservoir, correspondence between the power output/consumption in the weekly load schedule, turning to account of the water resource at maximum overall efficiencies, etc. Maximization of the net energy value (generated minus consumed) was selected as performance function of the model, considering the differentiated price of the electric energy over the week (working or weekend days, peak, half-peak or base hours). The analysis time step was required to be of 3 hours, resulting a weekly horizon of 56 steps and 168 decision variables, respectively, for the 3 HPPs of the system. These were allowed to be the flows turbined at the HPP and the number of working hydrounits at PSP, on each time step. The numerical application has considered the guiding data of Fantanele-Tarnita-Lapustesti hydroelectric development. Results of various simulations carried out proved the qualities of the proposed optimization model, which will allow its use within a decisional support program for such a development.

  5. Sonographic features of lethal multiple pterygium syndrome at 14 weeks.

    Science.gov (United States)

    Chen, Min; Chan, Gavin Shueng Wai; Lee, Chin Peng; Tang, Mary Hoi Yin

    2005-06-01

    Lethal multiple pterygium syndrome is a rare inherited disorder. Previous reports suggest that the diagnosis may be based on prenatal sonographic demonstration of severe limb flexion, absence of fetal motion, and a large cystic hygroma in the second and third trimesters. We present the sonographic features and postmortem features of a fetus with lethal multiple pterygium syndrome at 13 weeks of gestation, which shows that the condition can possibly be diagnosed in the first trimester of pregnancy.

  6. AGOR 28: SIO Shipyard Representative Bi-Weekly Progress Report

    Science.gov (United States)

    2016-06-18

    Sally Ride. • Two full 20-foot IOL shipping containers scheduled for delivery DCI on Monday. • Spares Load out scheduled for next week. 4. Operator...the silty water. 2 • Anchor Windlass – Design using “ulster” chain guide is progressing. Yesterday’s development regarding foreign chain...J-1 at sustained speed. See Airborne Noise Survey Report (DI-032-006) for more information (Delete after RFW approved) 1137 HVAC - There were no

  7. Working-week flexibility: Implications for employment and productivity

    OpenAIRE

    Osune, Victoria

    2014-01-01

    This paper evaluates the implications for employment, productivity and wages of allowing for more flexibility in weekly hours worked introduced in the recent Spanish labour market reform (the 2012 reform). A crucial aspect of the model will be the extent to which firms will be able to choose the workweek when subject to demand shocks. The model is calibrated so that it reproduces the cross-sectional distribution of workweeks across plants and households and some features of the Spanish econom...

  8. A thirteen week ad libitum administration toxicity study of tartrazine ...

    African Journals Online (AJOL)

    Tartrazine is a colorant widely used in food products, drugs and cosmetics. The current study evaluates the effect of sub-chronic ingestion of tartrazine in drinking water at doses of 0, 0.1, 0.45, 1 and 2.5% for 13 weeks in mice. Our results show that female body weight gain and food consumption decreased in all treated ...

  9. The marine biological week as an approach to science

    Science.gov (United States)

    Ransdorf, Angela; Satzinger, Viktoria

    2017-04-01

    The "Wiedner Gymnasium" is an academic high school with two branches: one focusses on languages and the other one on science. In the language branch the students learn at least three languages; one of which is Latin, whereas the students of the scientific branch can learn geometrical drawing and have to attend a scientific laboratory throughout the last four upper classes. As incentive highlights the language classes have a one week's school trip to France, Italy or Spain at the beginning of their 7th form in order to attend a language school and to practice their language skills. As a counterbalance, there was introduced the "marine biological week" several years ago, in which the students of the scientific branch take part whilst their colleagues have their language trips. The marine biological week takes place in Rovinj, Croatia. A team of biologists and divers leads through a programme, by which the students get an overview of different habitats, their conditions and the different ways of adaptation organisms find. Thus, they also become acquainted with several species of animals and plants which are characteristic for this area. They become familiar with some methods of scientific work and also get to know some of the problems marine ecosystems are confronted with. They also learn a little bit if the Mediterranean history and culture. Back in school all the findings are reviewed and brought into an ecological context. The insights can be used for many other topics, too, such as e.g. evolution. This week has proved to be a good start as well for the topic of ecology as for learning to think scientifically in general. So, you can call it a pivot for the scientific branch of our school.

  10. Nonparametric Efficiency Testing of Asian Stock Markets Using Weekly Data

    OpenAIRE

    CORNELIS A. LOS

    2004-01-01

    The efficiency of speculative markets, as represented by Fama's 1970 fair game model, is tested on weekly price index data of six Asian stock markets - Hong Kong, Indonesia, Malaysia, Singapore, Taiwan and Thailand - using Sherry's (1992) non-parametric methods. These scientific testing methods were originally developed to analyze the information processing efficiency of nervous systems. In particular, the stationarity and independence of the price innovations are tested over ten years, from ...

  11. Gastrointestinal tolerability with ibandronate after previous weekly bisphosphonate treatment.

    Science.gov (United States)

    Derman, Richard; Kohles, Joseph D; Babbitt, Ann

    2009-01-01

    Data from two open-label trials (PRIOR and CURRENT) of women with postmenopausal osteoporosis or osteopenia were evaluated to assess whether monthly oral and quarterly intravenous (IV) ibandronate dosing improved self-reported gastrointestinal (GI) tolerability for patients who had previously experienced GI irritation with bisphosphonate (BP) use. In PRIOR, women who had discontinued daily or weekly BP treatment due to GI intolerance received monthly oral or quarterly IV ibandronate for 12 months. The CURRENT subanalysis included women receiving weekly BP treatment who switched to monthly oral ibandronate for six months. GI symptom severity and frequency were assessed using the Osteoporosis Patient Satisfaction Questionnaire. In PRIOR, mean GI tolerability scores increased significantly at month 1 from screening for both treatment groups (oral: 79.3 versus 54.1; IV: 84.4 versus 51.0; p 90% at Month 10). In the CURRENT subanalysis >60% of patients reported improvements in heartburn or acid reflux and >70% indicated improvement in other stomach upset at month 6. Postmenopausal women with GI irritability with daily or weekly BPs experienced improvement in symptoms with extended dosing monthly or quarterly ibandronate compared with baseline.

  12. PROCTITIS ONE WEEK AFTER STEREOTACTIC BODY RADIATION THERAPY FOR PROSTATE CANCER: IMPLICATIONS FOR CLINICAL TRIAL DESIGN

    Directory of Open Access Journals (Sweden)

    Ima Paydar

    2016-07-01

    Full Text Available Background: Proctitis following prostate cancer radiation therapy is a primary determinant of quality of life (QOL. While previous studies have assessed acute rectal morbidity at 1 month after stereotactic body radiotherapy (SBRT, little data exist on the prevalence and severity of rectal morbidity within the first week following treatment. This study reports the acute bowel morbidity one week following prostate SBRT. Materials and methods: Between May 2013 and August 2014, 103 patients with clinically localized prostate cancer were treated with 35 to 36.25 Gy in five fractions using robotic SBRT delivered on a prospective clinical trial. Bowel toxicity was graded using the Common Terminology Criteria for Adverse Events version 4.0 (CTCAEv.4. Bowel QOL was assessed using EPIC-26 questionnaire bowel domain at baseline, one week, one month, and three months. Time-dependent changes in bowel symptoms were statistically compared using the Wilcoxon signed-rank test. Clinically significant change was assessed by the minimally important difference (MID in EPIC score. This was defined as a change of one-half standard deviation (SD from the baseline score. Results: One hundred and three patients with a minimum of three months of follow-up were analyzed. The cumulative incidence of acute grade 2 GI toxicity was 23%. There were no acute ≥ grade 3 bowel toxicities. EPIC bowel summary scores maximally declined at 1 week after SBRT (-13.9, p<0.0001 before returning to baseline at three months after SBRT (+0.03, p=0.94. Prior to treatment, 4.9% of men reported that their bowel bother was a moderate to big problem. This increased to 28.4% (p<0.0001 one week after SBRT and returned to baseline at three months after SBRT (0.0%, p=0.66. Only the bowel summary and bowel bother score declines at 1 week met the MID threshold for clinically significant change. Conclusion: The rate and severity of acute proctitis following prostate SBRT peaked at one week after

  13. Prenatal magnetic resonance imaging: brain normal linear biometric values below 24 gestational weeks

    International Nuclear Information System (INIS)

    Parazzini, C.; Righini, A.; Triulzi, F.; Rustico, M.; Consonni, D.

    2008-01-01

    Prenatal magnetic resonance (MR) imaging is currently used to measure quantitative data concerning brain structural development. At present, morphometric MR imaging studies have been focused mostly on the third trimester of gestational age. However, in many countries, because of legal restriction on abortion timing, the majority of MR imaging fetal examination has to be carried out during the last part of the second trimester of pregnancy (i.e., before the 24th week of gestation). Accurate and reliable normative data of the brain between 20 and 24 weeks of gestation is not available. This report provides easy and practical parametric support to assess those normative data. From a database of 1,200 fetal MR imaging studies, we retrospectively selected 84 studies of the brain of fetuses aged 20-24 weeks of gestation that resulted normal on clinical and radiological follow-up. Fetuses with proved or suspected infections, twin pregnancy, and fetuses of mothers affected by pathology that might have influenced fetal growth were excluded. Linear biometrical measurements of the main cerebral structures were obtained by three experienced pediatric neuroradiologists. A substantial interobserver agreement for each measurements was reached, and normative data with median, maximum, and minimum value were obtained for brain structures. The knowledge of a range of normality and interindividual variability of linear biometrical values for the developing brain between 20th and 24th weeks of gestation may be valuable in assessing normal brain development in clinical settings. (orig.)

  14. EVALUATION OF SOME BIOCHEMICAL PARAMETERS IN RABBITS BLOOD AFTER TWO WEEKS EXPOSURE OF EPICATECHIN

    Directory of Open Access Journals (Sweden)

    Katarina Zbynovska

    2014-02-01

    Full Text Available The aim of present study was to analyse biochemical parameters in blood of rabbits after epicatechin administration during two weeks. Animals (adult female rabbits, body weight 4 ± 0.5 kg were divided into four groups: control group (C and experimental groups (E1 – E3. Experimental groups received epicatechin in injectable form at 10 µg.kg-1 in E1, 100 µg.kg-1 in E2 and 1000 µg.kg-1 in E3 for 14 days three times a week. After two weeks of exposure the blood was collected, in blood serum selected biochemical parameters [(glucose, urea, bilirubin, cholesterol, triglycerides, total proteins, calcium (Ca2+, magnesium (Mg2+, phosphorus (P] were analysed by automatic analyzer Microlab 300 (Merck®, Germany. Potassium (K+, sodium (Na+, chlorides (Cl- were analysed by EasyLyte Plus (Medica Corporation, USA. Epicatechin had no significant influence on the observed parameters (P > 0.05. The present study has shown that the serum cholesterol level and triglycerides levels in the E2 and E3 groups were higher than in the control group, however without significant differences (P > 0.05. Two weeks exposure of epicatehin caused also insignificant increase of glucose in all experimental groups in comparison with the control group. Epicatechin had no effect on the others analysed biochemical parameters.

  15. Effects of 16-weeks of Pilates on health perception and sleep quality among elderly women.

    Science.gov (United States)

    Curi, V S; Vilaça, J; Haas, A N; Fernandes, H M

    2018-01-01

    The objective of this study was to determine the effect of 16 weeks of mat-based Pilates training on health perception and sleep quality among elderly women. A randomized and controlled trial was conducted in Caxias do Sul, Brazil, in 2015, in which 61 healthy older women were divided into two groups: experimental group (EG; n=31, average of 64.25 years old, SD 0.14) and control group (CG; n=30, average of 63.75 years old, SD 0.08). The EG participants performed mat-based Pilates exercises twice a week in 60-min sessions, whereas the CG did not train. All participants completed Brazilian-adapted and validated versions of the Pittsburgh Sleep Quality Index (PSQI-BR) and General Health Questionnaire (GHQ-12) at baseline and after 16 weeks. Significant time x group interaction effects were found for the GHQ-12 total score (pPilates EG when compared to the CG. All significant effects were classified as moderate to high. These results indicate that 16 weeks of mat-based Pilates training significantly improves the perceived health status and some sleep quality indices among elderly women. However, more studies are needed to assess the effectiveness of equipment-based Pilates exercises among this population. Copyright © 2017 Elsevier B.V. All rights reserved.

  16. Prenatal magnetic resonance imaging: brain normal linear biometric values below 24 gestational weeks

    Energy Technology Data Exchange (ETDEWEB)

    Parazzini, C.; Righini, A.; Triulzi, F. [Children' s Hospital ' ' V. Buzzi' ' , Department of Radiology and Neuroradiology, Milan (Italy); Rustico, M. [Children' s Hospital ' ' V. Buzzi' ' , Department of Obstetrics and Gynecology, Milan (Italy); Consonni, D. [Fondazione IRCCS Ospedale Maggiore Policlinico, Unit of Epidemiology, Milan (Italy)

    2008-10-15

    Prenatal magnetic resonance (MR) imaging is currently used to measure quantitative data concerning brain structural development. At present, morphometric MR imaging studies have been focused mostly on the third trimester of gestational age. However, in many countries, because of legal restriction on abortion timing, the majority of MR imaging fetal examination has to be carried out during the last part of the second trimester of pregnancy (i.e., before the 24th week of gestation). Accurate and reliable normative data of the brain between 20 and 24 weeks of gestation is not available. This report provides easy and practical parametric support to assess those normative data. From a database of 1,200 fetal MR imaging studies, we retrospectively selected 84 studies of the brain of fetuses aged 20-24 weeks of gestation that resulted normal on clinical and radiological follow-up. Fetuses with proved or suspected infections, twin pregnancy, and fetuses of mothers affected by pathology that might have influenced fetal growth were excluded. Linear biometrical measurements of the main cerebral structures were obtained by three experienced pediatric neuroradiologists. A substantial interobserver agreement for each measurements was reached, and normative data with median, maximum, and minimum value were obtained for brain structures. The knowledge of a range of normality and interindividual variability of linear biometrical values for the developing brain between 20th and 24th weeks of gestation may be valuable in assessing normal brain development in clinical settings. (orig.)

  17. Factors associated with delivery at or after 28 weeks gestation in women with bulging fetal membranes before 26 weeks gestation.

    Science.gov (United States)

    Ito, Akiko; Maseki, Yoshiaki; Ikeda, Sayako; Tezuka, Atsuko; Kuribayashi, Momoko; Furuhashi, Madoka

    2017-09-01

    To elucidate the factors that contribute to prolonged pregnancy and promote neonate survival in women with bulging fetal membranes. A database was reviewed to identify women with singleton pregnancies who underwent amniocentesis on admission to determine amniotic fluid neutrophil elastase levels before 26 + 0 weeks gestation between July 2001 and January 2015. Following delivery, the placentas of these patients were examined for histologic chorioamnionitis. Ninety-seven women delivered before 28 weeks gestation, and 117 women delivered at or after 28 weeks gestation. Rescue cerclage performed via the McDonald procedure (adjusted odds ratio [aOR]: 3.78; 95% confidence interval [CI]: 1.35-11.80) was associated with a higher likelihood of reaching at least 28 weeks gestation before delivery, whereas protruding membranes (aOR: 0.38; 95% CI: 0.18-0.78), elevated amniotic neutrophil elastase levels (≥0.15 μg/ml) (aOR, 0.41; 95% CI: 0.20-0.82) and elevated peripheral C-reactive protein levels (≥0.4 mg/dl) (aOR: 0.34; 95% CI: 0.180.65) were associated with a significantly reduced likelihood of reaching this gestational age before delivery. Among women who underwent rescue cerclage, amniorrhexis was associated with a negative prognosis (aOR: 0.18; 95% CI: 0.05-0.51). Intra-amniotic inflammation, protrusion of fetal membranes and amniorrhexis are factors that may prevent pregnancy prolongation. Rescue cerclage improves pregnancy outcomes.

  18. Effects of prolonged stress on salivary cortisol and dehydroepiandrosterone: a study of a two-week teaching practice.

    Science.gov (United States)

    Izawa, Shuhei; Saito, Keisuke; Shirotsuki, Kentaro; Sugaya, Nagisa; Nomura, Shinobu

    2012-06-01

    This study investigated variations in salivary levels of cortisol and dehydroepiandrosterone (DHEA) in a prolonged stressful situation (a two-week teaching practice). Thirty-three women for whom a two-week teaching practice at a kindergarten was scheduled were asked to collect saliva samples at awakening, 30 min after awakening, and bedtime at four time points: two weeks before the practice, the first week of the practice, the second week of the practice, and a few days after the practice. In addition, they completed questionnaires for assessing perceived stress and subjective moods on each day. A linear mixed model indicated that cortisol levels significantly increased during the first and second week of the practice compared with those before and after the practice period, and that DHEA levels significantly decreased after the practice period compared with those at the other time points. Further, cortisol awakening response after the practice period significantly reduced compared with that at the other time points. Scores of perceived stress and negative moods were also higher during the practice period. This study showed that prolonged stress affected cortisol and DHEA secretion during as well as after the stress period. Copyright © 2011 Elsevier Ltd. All rights reserved.

  19. Measurement of weekly prostate specific antigen levels in patients receiving pelvic radiotherapy for nonprostatic malignancies

    International Nuclear Information System (INIS)

    Vijayakumar, Srinivasan; Quadri, S. Farhat; Sen, Saunak; Vaida, Florin; Ignacio, Lani; Weichselbaum, R. R.

    1995-01-01

    Purpose: To study the response of nonmalignant prostatic tissue to ionizing irradiation in terms of the resultant changes in serum prostate specific antigen (PSA) levels. Methods and Materials: Weekly serum PSA values were determined during radiotherapy (RT) in nine patients ('treatment group') without clinical evidence of prostate cancer (PC), and who received pelvic RT for other indications. Slopes for the rate of change in PSA was determined using model: log PSA = β0 + β1 * week + β2 * week 2 + error. These results are compared with 17 normal volunteers ('control group') who were not exposed to ionizing irradiation. An attempt is made to compare any similarities and differences in subsets of 64 T1-T4N0M0 PC patients who received pelvic RT. Results: An elevation in the serum PSA levels were noted in eight of nine patients in the 'treatment group' with a median time of 4.2 weeks to reach the maximum serum PSA values. After an initial increase, PSA values declined. In some patients, manifold increase in PSA was noted, for example, from 1.8 to 13.5 ng/ml and 3.3 to 9.8 ng/ml in two patients. The PSA increase ranged from 50-650%. The median slope was 0.601 week -1 (range 0.192-3.045 week -1 ). No such increases were seen in the 'control group' (median slope = 0.03 week -1 ; range, 0.18-0.13 week -1 ). When differences between the mean increase/decrease for each week compared to pretreatment values were analyzed, the irradiated group had statistically significant elevations in the PSA for weeks 3 (p = 0.034), 4 (p = 0.035), and 5 (p 0.024). A similar trend of increasing PSA levels during radiotherapy was noted in prostate cancer patients whose initial PSA values were ≤ 20 ng/ml: whereas positive slopes (i.e., increasing PSA levels during radiotherapy course) was seen in 7.1% of those with > 20 ng/ml preradiotherapy PSA values, such trends were seen in 52.7% of those with ≤ 20 ng/ml preradiotherapy PSA values. Conclusions: (a) Incidental exposure of noncancerous

  20. Measurement of weekly prostate specific antigen levels in patients receiving pelvic radiotherapy for nonprostatic malignancies

    Energy Technology Data Exchange (ETDEWEB)

    Vijayakumar, Srinivasan; Quadri, S Farhat; Sen, Saunak; Vaida, Florin; Ignacio, Lani; Weichselbaum, R R

    1995-04-30

    Purpose: To study the response of nonmalignant prostatic tissue to ionizing irradiation in terms of the resultant changes in serum prostate specific antigen (PSA) levels. Methods and Materials: Weekly serum PSA values were determined during radiotherapy (RT) in nine patients ('treatment group') without clinical evidence of prostate cancer (PC), and who received pelvic RT for other indications. Slopes for the rate of change in PSA was determined using model: log PSA = {beta}0 + {beta}1{sup *}week + {beta}2{sup *}week{sup 2} + error. These results are compared with 17 normal volunteers ('control group') who were not exposed to ionizing irradiation. An attempt is made to compare any similarities and differences in subsets of 64 T1-T4N0M0 PC patients who received pelvic RT. Results: An elevation in the serum PSA levels were noted in eight of nine patients in the 'treatment group' with a median time of 4.2 weeks to reach the maximum serum PSA values. After an initial increase, PSA values declined. In some patients, manifold increase in PSA was noted, for example, from 1.8 to 13.5 ng/ml and 3.3 to 9.8 ng/ml in two patients. The PSA increase ranged from 50-650%. The median slope was 0.601 week{sup -1} (range 0.192-3.045 week{sup -1}). No such increases were seen in the 'control group' (median slope = 0.03 week{sup -1}; range, 0.18-0.13 week{sup -1}). When differences between the mean increase/decrease for each week compared to pretreatment values were analyzed, the irradiated group had statistically significant elevations in the PSA for weeks 3 (p = 0.034), 4 (p = 0.035), and 5 (p 0.024). A similar trend of increasing PSA levels during radiotherapy was noted in prostate cancer patients whose initial PSA values were {<=} 20 ng/ml: whereas positive slopes (i.e., increasing PSA levels during radiotherapy course) was seen in 7.1% of those with > 20 ng/ml preradiotherapy PSA values, such trends were seen in 52.7% of those with {<=} 20 ng/ml preradiotherapy PSA values

  1. Small Worlds Week: Raising Curiosity and Contributing to STEM

    Science.gov (United States)

    Ng, C.; Mayo, L.; Stephenson, B. E.; Keck, A.; Cline, T. D.; Lewis, E. M.

    2015-12-01

    Dwarf planets, comets, asteroids, and icy moons took center stage in the years 2014-2015 as multiple spacecraft (New Horizons, Dawn, Rosetta, Cassini) and ground-based observing campaigns observed these small and yet amazing celestial bodies. Just prior to the historic New Horizons encounter with the Pluto system, NASA celebrated Small Worlds Week (July 6-10) as a fully online program to highlight small worlds mission discoveries. Small Worlds Week leveraged the infrastructure of Sun-Earth Days that included a robust web design, exemplary education materials, hands-on fun activities, multimedia resources, science and career highlights, and a culminating event. Each day from July 6-9, a new class of solar system small worlds was featured on the website: Monday-comets, Tuesday-asteroids, Wednesday-icy moons, and Thursday-dwarf planets. Then on Friday, July 10, nine scientists from Goddard Space Flight Center, Jet Propulsion Laboratory, Naval Research Laboratory, and Lunar and Planetary Institute gathered online for four hours to answer questions from the public via Facebook and Twitter. Throughout the afternoon the scientists worked closely with a social media expert and several summer interns to reply to inquirers and to archive their chats. By all accounts, Small Worlds Week was a huge success. The group plans to improve and replicate the program during the school year with a more classroom focus, and then to build and extend the program to be held every year. For more information, visit http:// sunearthday.nasa.gov or catch us on Twitter, #nasasww.

  2. Gastrointestinal tolerability with ibandronate after previous weekly bisphosphonate treatment

    Directory of Open Access Journals (Sweden)

    Richard Derman

    2009-09-01

    Full Text Available Richard Derman1, Joseph D Kohles2, Ann Babbitt31Department of Obstetrics and Gynecology, Christiana Hospital, Newark, DE, USA; 2Roche, Nutley, NJ, USA; 3Greater Portland Bone and Joint Specialists, Portland, ME, USAAbstract: Data from two open-label trials (PRIOR and CURRENT of women with postmenopausal osteoporosis or osteopenia were evaluated to assess whether monthly oral and quarterly intravenous (IV ibandronate dosing improved self-reported gastrointestinal (GI tolerability for patients who had previously experienced GI irritation with bisphosphonate (BP use. In PRIOR, women who had discontinued daily or weekly BP treatment due to GI intolerance received monthly oral or quarterly IV ibandronate for 12 months. The CURRENT subanalysis included women receiving weekly BP treatment who switched to monthly oral ibandronate for six months. GI symptom severity and frequency were assessed using the Osteoporosis Patient Satisfaction Questionnaire™. In PRIOR, mean GI tolerability scores increased significantly at month 1 from screening for both treatment groups (oral: 79.3 versus 54.1; IV: 84.4 versus 51.0; p < 0.001 for both. Most patients reported improvement in GI symptom severity and frequency from baseline at all post-screening assessments (>90% at Month 10. In the CURRENT subanalysis >60% of patients reported improvements in heartburn or acid reflux and >70% indicated improvement in other stomach upset at month 6. Postmenopausal women with GI irritability with daily or weekly BPs experienced improvement in symptoms with extended dosing monthly or quarterly ibandronate compared with baseline.Keywords: ibandronate, osteoporosis, bisphosphonate, gastrointestinal

  3. Comparing between results and complications of doing voiding cystourethrogram in the first week following urinary tract infection and in 2-6 weeks after urinary tract infection in children referring to a teaching hospital.

    Science.gov (United States)

    Yousefichaijan, Parsa; Dorreh, Fatemeh; Shahsavari, Someyeh; Pakniyat, Abdolghader

    2016-01-01

    Urinary tract infection is the most common genitourinary disease in children so about 40% of the children with urinary tract infection suffering from reflux that caused some consequences such as pyelonephritis and kidney parenchymal injury. This research was conducted to compare the timing of voiding cystourethrogram (VCUG) in children with urinary tract infection in first week and after the first week of urinary tract infection. This research is a case-control study that both case and control groups include 208 children from 1 month to 12 years old with the complain of urinary tract infection. In case group, the VCUG was performed at the first week of infection and in control group, the VCUG was performed after the first week of infection. complication such as dysuria was observed in two-thirds of children who VCUG was performed during first week after urinary tract infection. Parents stress in case group was more than the other (P=0.015). For overall, the incidence of reflux in case and control groups was 49.5% and 50%, respectively. The mean of reflux grading in right kidney in case group was lower than control group resulting in significant differences between two groups. According to higher grade of stress in parents and complications due to VCUG at the first week of urinary tract infection, it is suggested that VCUG be conducted on selective patients in the hospital at the first week of urinary tract infection and during hospitalization.

  4. SPIRAL2 Week 2012 - Slides of the presentations

    International Nuclear Information System (INIS)

    Staley, F.; Jacquemet, M.; Lewitowicz, M.; Bertrand, P.; Tuske, O.; Caruso, A.; Leyge, J.F.; Perrot, L.; Di Giacomo, M.; Ausset, P.; Moscatello, M.H.; Savalle, A.; Rannou, B.; Lambert, M.; Petit, E.; Hulin, X.; Barre-Boscher, N.; Tusseau-Nenez, S.; Tecchio, L.B.

    2013-01-01

    The main goal of the 5. edition of the SPIRAL2 Week is to present and discuss the current status of the SPIRAL2 project in front of a large community of scientists and engineers. The program of the meeting will include presentations on scientific and technical developments related to the baseline project, experiments and theory. The main topics to be discussed at the conference are: -) physics and detectors at SPIRAL2, -) driver accelerators, -) production of radioactive ion beams (RIB), -) safety, -) buildings and infrastructure, -) RIB facilities worldwide, and -) SPIRAL2 preparatory phase. This document is made up of the slides of the presentations

  5. Teaching Co-Design Games in Five Weeks

    DEFF Research Database (Denmark)

    Brandt, Eva; Kjærgård, Sarasiff; Risak Schou, Gudrun

    2011-01-01

    . It is important in order to prepare students for a career as designers. The paper reports from an intense five weeks course about developing and using design games as a frame for design-oriented collaborations with people outside the core design team. Co-design is about making room for people with diverse...... interests, roles and responsibilities in rehearsing the future. Using the game metaphor to stage and engage everyone is a valuable format for collaborative inquiry and co-creating future visions – in other words exploring diversity and creating unity about values and goals. The professional designer...

  6. Earth Science Week 2009, "Understanding Climate", Highlights and News Clippings

    Energy Technology Data Exchange (ETDEWEB)

    Robeck, Edward C. [American Geological Inst., Alexandria, VA (United States)

    2010-01-05

    The American Geological Institute (AGI) proposes to expand its influential Earth Science Week Program in 2009, with the support of the U.S. Department of Energy, to disseminate DOE's key messages, information, and resources on climate education and to include new program components. These components, ranging from online resources to live events and professional networks, would significantly increase the reach and impact of AGI's already successful geoscience education and public awareness effort in the United States and abroad in 2009, when the campaign's theme will be "Understanding Climate."

  7. Change in perceived psychosocial status following a 12-week Tai Chi exercise programme.

    Science.gov (United States)

    Taylor-Piliae, Ruth E; Haskell, William L; Waters, Catherine M; Froelicher, Erika Sivarajan

    2006-05-01

    This paper reports a study to examine change in psychosocial status following a 12-week Tai Chi exercise intervention among ethnic Chinese people with cardiovascular disease risk factors living in the United States of America. Regular participation in physical activity is associated with protection against cardioavascular disease, and improvements in physical and psychological health. Increasing amounts of scientific evidence suggests that mind-body exercise, such as Tai Chi, are related to improvements in mental health, emotional well-being, and stress reduction. No prior study has examined the effect of a Tai Chi exercise intervention on psychosocial status among people with cardiovascular disease risk factors. This was a quasi-experimental study. Participants attended a 60-minute Tai Chi exercise class three times per week for 12 weeks. Data were collected at baseline, 6 and 12 weeks following the intervention. Psychosocial status was assessed using Chinese versions of Cohen's Perceived Stress Scale, Profile of Mood States, Multidimensional Scale of Perceived Social Support, and Tai Chi exercise self-efficacy. A total of 39 participants, on average 66-year-old (+/-8.3), married (85%), Cantonese-speaking (97%), immigrants participated. The majority were women (69%), with social support (eta2 = 0.12). Tai Chi was a culturally appropriate mind-body exercise for these older adults, with statistically significant psychosocial benefits observed over 12-weeks. Further research examining Tai Chi exercise using a randomized clinical trial design with an attention-control group may reduce potential confounding effects, while exploring potential mechanisms underlying the relaxation response associated with mind-body exercise. In addition, future studies with people with other chronic illnesses in all ethnic groups are recommended to determine if similar benefits can be achieved.

  8. Physical performance in recently aged adults after 6 weeks traditional Thai dance: a randomized controlled trial

    Science.gov (United States)

    Janyacharoen, Taweesak; Laophosri, Maneepun; Kanpittaya, Jaturat; Auvichayapat, Paradee; Sawanyawisuth, Kittisak

    2013-01-01

    Background Exercise has been shown to be effective in cardiovascular endurance in the elderly. We studied the effect of Thai dancing on physical performance of Thai elderly. Methods This was an open-labeled, randomized intervention study. The Thai dancing group exercised for 40 minutes three times a week for 6 weeks. Physical performance ability was the primary outcome, including a 6-minute walk test (6MWT), five-times sit-to-stand (FTSST), and a sit-and-reach test measured before and after 6 weeks of intervention. Results There were 42 subjects enrolled in the study, and 38 female subjects completed (20 in Thai dance group, 18 controls), with an average age of 65.8 ± 5.1 years. The Thai dance group had significantly better physical performance in all measurements at the end of the study. The 6MWT was longer (416.7 ± 58.7 versus 345.7 ± 55.1 m; P = 0.011), FTSST was quicker (10.2 ± 1.5 versus 14.4 ± 3.3 seconds; P dance group than the control group. Conclusion Thai dance can improve physical performance in recently aged (elderly) female adults. PMID:23950640

  9. A clean environmental week: Let the nature breathe.

    Science.gov (United States)

    Moustafa, Khaled

    2017-11-15

    High levels of CO 2 emissions in the atmosphere and toxic pollutants in air, water and food have serious repercussions on all life's systems, including living beings, environment and economy. Everyone on the Earth is concerned by pollution in some way or another, no matter where and how the pollution is produced as airborne and foodborne pollutants could circulate around the world in different ways, through for example climate components (wind, rain) and/or import and export of foodstuffs. Similarly to living beings that take advantage of day-night circadian rhythms to recover after diurnal hardships, the environment in its entirety could also be seen as a complex living system that needs regular breaks to assimilate or ingest toxic pollutants produced during intensive and continuous industrial processes. If greenhouses gas emissions and pollution rates continue to increase at the same rates as they are nowadays, uncontrollable climate effects might be inevitable and the air quality in some crowded cities in the world might be hardly respirable in the future. A global "Clean Environmental Week" is discussed as an attempt toward reducing air pollution and CO 2 emissions through the interruption or reduction of industrial polluting activities regularly, for a week or so per year, to let the nature 'breathe' and recover from environmentally challenging pollutions. A clean environmental period of 10 days per year could reduce CO 2 emissions by about one billion tons of CO 2 per annum. Copyright © 2017 Elsevier B.V. All rights reserved.

  10. LHC 2012 proton run extended by seven weeks

    CERN Multimedia

    James Gillies

    2012-01-01

    An important piece of news that almost got lost in the excitement of the Higgs update seminar on 4 July is that the 2012 LHC proton run is to be extended.   On 3 July, a meeting was held between the CERN Management and representatives of the LHC and the experiments to discuss the merits of increasing the data target for this year in the light of the announcement to be made the following day. The conclusion was that an additional seven weeks of running would allow the luminosity goal for the year to be increased from 15 inverse femtobarns to 20, giving the experiments a good supply of data to work on during the LHC’s first long shut-down (LS1), and allowing them to make progress in determining the properties of the new particle whose discovery was announced last week. The current LHC schedule foresees proton running reaching a conclusion on 16 October, with a proton-ion run scheduled for November. In the preliminary new schedule, proton running is planned to continue until 16 December, ...

  11. Report from the June Trigger and Physics Week

    CERN Multimedia

    Chris Bee

    The week of June 4th saw the 5th ATLAS Trigger and Physics week at CERN. The meeting, bringing together people working in the trigger, data preparation, detector combined-performance and physics groups, aimed at focusing work and discussions on preparing ATLAS for first data-taking. The meeting started on Monday afternoon with a set of plenary presentations on topics ranging from software status and validation, the ATLAS analysis model and its implications for the computing model, and initial ideas for trigger menus for the expected LHC start-up luminosity of 1031cm-2s-1. There was also a report from Peter Jenni on the expected LHC start-up schedule. The participation exceeded the organisers' wildest dreams as the CERN Council Chamber (seating capacity 160) proved woefully inadequate to seat everyone. A packed Council Chamber for the opening plenary Tuesday was dedicated to parallel sessions of the trigger and combined performance groups. A great deal of progress was presented in all areas, notably on...

  12. The ATLAS Overview Week in Freiburg, October 2004

    CERN Multimedia

    Smith, K.

    2004-01-01

    The first things that must be said are that the city of Freiburg is a very attractive location for such a meeting, encouraging a relaxed coming together of all sections of the ATLAS Community, and that the Week's activities were splendidly, (while unobtrusively), organised by our hosts, Karl Jakobs and Gregor Herten and their supporting team. The fine sunny weather contributed to our sense of well-being, of course, as did the quality of the local beer! (Some of our native English speaking colleagues were relieved to discover that what was described in restaurants and bars as 'Badisch' turned out, on the contrary, to be rather 'Good-ish' instead!!) The week began with pre-meetings of subgroups on Saturday and Sunday, and included lively discussions on how to commission the detector and on the nature and format of the ATLAS control room and its environs. These discussions were a clear indication of the optimism within the ATLAS community that physics is really beginning to appear on our horizon! During th...

  13. Maternal and perinatal outcomes during expectant management of 239 severe preeclamptic women between 24 and 33 weeks' gestation.

    Science.gov (United States)

    Haddad, Bassam; Deis, Stéphanie; Goffinet, François; Paniel, Bernard J; Cabrol, Dominique; Siba, Baha M

    2004-06-01

    This study was undertaken to determine maternal and perinatal outcomes after expectant management of severe preeclampsia between 24 and 33 weeks' gestation. A prospective observational study of 239 women with severe preeclamptic and undelivered after antenatal steroid prophylaxis was performed. Pregnancy prolongation and maternal and perinatal morbidities were analyzed according to the gestational age at time of expectant management: 24 to 28, 29 to 31, and 32 to 33 weeks. Statistical analysis was performed by Student t test and chi(2) test. The days of pregnancy prolongation were significantly higher among those managed at less than 29 weeks (6) compared with the other groups (4). There were 13 perinatal deaths: 12 in those managed at less than 29 weeks and 1 in those managed at 29 to 31 weeks. Neonatal morbidities were significantly higher among those managed at less than 29 weeks compared with the other groups. There were no instances of maternal death or eclampsia. Maternal morbidities were similar among the groups. Expectant management of severe preeclampsia at 24 to 33 weeks in a tertiary care center is associated with good perinatal outcome with a minimal risk for the mother.

  14. Twice-weekly aripiprazole for treating children and adolescents with tic disorder, a randomized controlled clinical trial.

    Science.gov (United States)

    Ghanizadeh, Ahmad

    2016-01-01

    Treating tic disorder is challenging. No trial has ever examined whether twice weekly aripiprazole is effective for treating tic disorders. Participants of this 8-week randomized controlled parallel-group clinical trial were a clinical sample of 36 children and adolescents with tic disorder. Yale global tic severity scale was used to assess the outcome. Both groups received daily dosage of aripiprazole for the first 14 days. Then, one group received daily dose of aripiprazole while the other group received twice weekly dosage of aripiprazole for the next 46 days. The patients were assessed at baseline, week 2, 4, and 8. Tic scores decreased in both group significantly 22.8 (18.5) versus 22.0 (11.6). Moreover, there was no between group difference. The final mean (SD) score of motor and vocal tics in the group treated with daily treatment was not significantly different from the twice weekly group (Cohen's d = 0.36). The odds ratios for sedation and increased appetite were 3.05 and 3, respectively. For the first time, current findings support that twice weekly aripiprazole efficacy was not different from that of daily treatment. The rate of drowsiness in the twice weekly treatment group was less than that of the daily treatment group. This trial was registered at http://www.irct.ir. The registration number of this trial was: IRCT201312263930N32. http://www.irct.ir/searchresult.php?id=3930&number=32.

  15. Conference Report: The 2016 Olten Meeting at the Basel Life Science Week.

    Science.gov (United States)

    Heinzelmann, Elsbeth

    2016-12-21

    "This 'telephone' has too many shortcomings to be seriously considered as a means of communication. The device is inherently of no value to us." This was an internal memo written by Western Union in 1876. That's right. Without efficient knowledge sharing and technology transfer, even the best scientific development may prove to be a damp squib for a long time. The Basel Life Science Week was created in order to promote scientific and economic exchange and pave the way for innovative ideas. That's why NTN Swiss Biotech has moved its traditional 'Olten Meeting' to the Basel Life Science Week. It is the ideal setting for NTN Swiss Biotech and the School of Life Sciences FHNW to present innovative developments within its network of academic and industrial partners in the future-oriented disciplines of Molecular Diagnostics and Medicinal Chemistry. Short summaries of the key lectures are reported below.

  16. Laparotomic Myomectomy in the 16th Week of Pregnancy: A Case Report

    Directory of Open Access Journals (Sweden)

    Lavinia Domenici

    2014-01-01

    Full Text Available Myomectomy is rarely performed during an ongoing pregnancy because of fear of miscarriage and the risk of an uncontrolled haemorrhage necessitating a hysterectomy. In cases where myomectomy is undertaken, most are performed at the time of cesarean section or with a laparoscopic approach. We report a case of a successful laparotomic myomectomy in the 16th week of pregnancy. A 35-year-old primigravida was admitted to our department with acute abdominal pain and hydronephrosis (serum creatinine 1.6 mg/dL. Imaging revealed a large implant myoma compressing the bladder, ureters, rectus, and gestational chamber and causing hydronephrosis. Laparotomic myomectomy was successfully performed and pregnancy continued uneventfully until the 38th week when a cesarean section was performed. Surgical management of myomas during pregnancy is worth evaluating in well-selected and highly symptomatic cases.

  17. Myogenic response of human skeletal muscle to 12 weeks of resistance training at light loading intensity

    DEFF Research Database (Denmark)

    Mackey, Abigail; Holm, L; Reitelseder, S

    2011-01-01

    There is strong evidence for enhanced numbers of satellite cells with heavy resistance training. The satellite cell response to very light muscle loading is, however, unknown. We, therefore, designed a 12-week training protocol where volunteers trained one leg with a high load (H) and the other leg...... with a light load (L). Twelve young healthy men [mean age 25 ± 3 standard deviation (SD) years] volunteered for the study. Muscle biopsies were collected from the m. vastus lateralis of both legs before and after the training period and satellite cells were visualized by CD56 immunohistochemistry....... A significant main effect of time was observed (P12 ± 0.03 to 0.15 ± 0.05, mean ± SD). The finding that 12 weeks of training skeletal muscle even with very light loads can induce an increase in the number of satellite...

  18. Can weekly noise levels of urban road traffic, as predominant noise source, estimate annual ones?

    Science.gov (United States)

    Prieto Gajardo, Carlos; Barrigón Morillas, Juan Miguel; Rey Gozalo, Guillermo; Vílchez-Gómez, Rosendo

    2016-11-01

    The effects of noise pollution on human quality of life and health were recognised by the World Health Organisation a long time ago. There is a crucial dilemma for the study of urban noise when one is looking for proven methodologies that can allow, on the one hand, an increase in the quality of predictions, and on the other hand, saving resources in the spatial and temporal sampling. The temporal structure of urban noise is studied in this work from a different point of view. This methodology, based on Fourier analysis, is applied to several measurements of urban noise, mainly from road traffic and one-week long, carried out in two cities located on different continents and with different sociological life styles (Cáceres, Spain and Talca, Chile). Its capacity to predict annual noise levels from weekly measurements is studied. The relation between this methodology and the categorisation method is also analysed.

  19. Effects of Twice-Weekly Intense Aerobic Exercise in Early Subacute Stroke: A Randomized Controlled Trial.

    Science.gov (United States)

    Sandberg, Klas; Kleist, Marie; Falk, Lars; Enthoven, Paul

    2016-08-01

    To examine the effects of 12 weeks of twice-weekly intensive aerobic exercise on physical function and quality of life after subacute stroke. Randomized controlled trial. Ambulatory care. Patients (N=56; 28 women) aged ≥50 years who had a mild stroke (98% ischemic) and were discharged to independent living and enrolled 20 days (median) after stroke onset. Sixty minutes of group aerobic exercise, including 2 sets of 8 minutes of exercise with intensity up to exertion level 14 or 15 of 20 on the Borg rating of perceived exertion scale, twice weekly for 12 weeks (n=29). The nonintervention group (n=27) received no organized rehabilitation or scheduled physical exercise. Primary outcome measures included aerobic capacity on the standard ergometer exercise stress test (peak work rate) and walking distance on the 6-minute walk test (6MWT). Secondary outcome measures included maximum walking speed for 10m, balance on the timed Up and Go (TUG) test and single leg stance (SLS), health-related quality of life on the European Quality of Life Scale (EQ-5D), and participation and recovery after stroke on the Stroke Impact Scale (SIS) version 2.0 domains 8 and 9. Participants were evaluated pre- and postintervention. Patient-reported measures were also evaluated at 6-month follow-up. The following improved significantly more in the intervention group (pre- to postintervention): peak work rate (group × time interaction, P=.006), 6MWT (P=.011), maximum walking speed for 10m (Pbalance, health-related quality of life, and patient-reported recovery. Copyright © 2016 American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved.

  20. Effect of preservation method on spider monkey (Ateles geoffroyi) fecal microbiota over 8 weeks.

    Science.gov (United States)

    Hale, Vanessa L; Tan, Chia L; Knight, Rob; Amato, Katherine R

    2015-06-01

    Studies of the gut microbiome have become increasingly common with recent technological advances. Gut microbes play an important role in human and animal health, and gut microbiome analysis holds great potential for evaluating health in wildlife, as microbiota can be assessed from non-invasively collected fecal samples. However, many common fecal preservation protocols (e.g. freezing at -80 °C) are not suitable for field conditions, or have not been tested for long-term (greater than 2 weeks) storage. In this study, we collected fresh fecal samples from captive spider monkeys (Ateles geoffroyi) at the Columbian Park Zoo (Lafayette, IN, USA). The samples were pooled, homogenized, and preserved for up to 8 weeks prior to DNA extraction and sequencing. Preservation methods included: freezing at -20 °C, freezing at -80 °C, immersion in 100% ethanol, application to FTA cards, and immersion in RNAlater. At 0 (fresh), 1, 2, 4, and 8 weeks from fecal collection, DNA was extracted and microbial DNA was amplified and sequenced. DNA concentration, purity, microbial diversity, and microbial composition were compared across all methods and time points. DNA concentration and purity did not correlate with microbial diversity or composition. Microbial composition of frozen and ethanol samples were most similar to fresh samples. FTA card and RNAlater-preserved samples had the least similar microbial composition and abundance compared to fresh samples. Microbial composition and diversity were relatively stable over time within each preservation method. Based on these results, if freezers are not available, we recommend preserving fecal samples in ethanol (for up to 8weeks) prior to microbial extraction and analysis. Copyright © 2015 Elsevier B.V. All rights reserved.

  1. Organ preservation in stage II and III head and neck cancer utilizing alternate week concomitant chemoradiotherapy

    International Nuclear Information System (INIS)

    Mansur, David B.; Vokes, Everett; Mittal, Bharat B.; Stenson, Kerstin; Kies, M.; Pelzer, H.; Nautiyal, Jaishanker; Kozloff, Mark; Weichselbaum, Ralph R.; Haraf, Daniel J.

    1996-01-01

    Purpose: A prospective phase II trial was conducted to determine the efficacy and rate of organ preservation of alternate week concomitant chemoradiotherapy in stage II and III head and neck cancer. Methods: Forty-nine patients (10 stage II and 39 stage III) with squamous cell carcinoma of the head and neck region have been entered into a prospective phase II trial. Pretreatment evaluation included history and physical examination, computed tomography of the neck, bone scan, chest x-ray, panendoscopy and biopsy confirmation of malignancy. Therapy is given in 2 week cycles consisting of 5 days of concomitant chemoradiotherapy followed by a nine day break during which no treatment is given. Each cycle of treatment consists of 1.0 gm hydroxyurea P.O. every 12 hours for 6 days (11 doses per cycle) and 800mg/m 2 /d continuous infusion 5-fluorouracil along with concomitant radiation therapy (RT) administered in 1.8-2.0 Gy daily fractions for five days. This alternate week (week on/week off) schedule is continued for a total of 7 cycles resulting in an overall treatment time of 13 weeks and a total RT dose of 70 Gy. Extent of initial surgery included biopsy only (59.2%), minimal laser debulking (12.2%), and resection with or without neck dissection (28.6%). Results: The majority of patients are male (71.4%), with a median age of 61.3 years. Primary sites included oral cavity (16.3%), oropharynx (12.2%), larynx (57.1%), hypopharynx (8.1%), and nasopharynx (4.1%). T stage included T3 (32 patients, 65.3%), T2 (16 patients, 32.7%), and T1 (1 patient). N stage included N1 (17 patients, 34.7%), and N0 (32 patients, 65.3%). With a median follow-up of 27 months, the overall response rate is 100% (91.7 complete response, and 8.3% partial response). The 5 year actuarial local control, disease free survival, and overall survival is 90.1%, 88.3%, and 65.0%, respectively. One patient has failed with distant disease alone. Four patients had isolated local failures and (3(4)) were

  2. The case of David: on the couch for sixty minutes, nine years of once-a-week treatment.

    Science.gov (United States)

    Kavaler-Adler, Susan

    2005-06-01

    This paper illustrates a unique case of object relations psychoanalytic psychotherapy on a once-a-week treatment basis. The work of developmental mourning that would be thought to require two to five sessions a week was accomplished on a once-a-week basis. The analyst adjusted the treatment hour, in this one case, to 60 minutes, as opposed to the 45- or 50-minute hour. When treatment began, the analyst made an intuitive judgment to increase the patient's one session a week--which the patient made clear was all he was ready to do--to 60 minutes. The analyst made time in her practice for this 60-minute session and has continued with the patient using this format for 9 years of treatment. This had led up to the current stage of treatment, which has been so critical to the patient's self-integration process.

  3. Local and Systemic Changes in Pain Sensitivity After 4 Weeks of Calf Muscle Stretching in a Nonpainful Population

    DEFF Research Database (Denmark)

    Bartholdy, Cecilie; Zangger, Graziella; Hansen, Lisbeth

    2016-01-01

    BACKGROUND: Stretching is often used in clinical practice for a variety of purposes, including pain therapy. The possible mechanism behind the effect of stretching remains to be clarified. AIM: To investigate whether 4 weeks of unilateral stretching of the calf muscles would affect local...... and central pain sensitivity. METHOD: This study was a randomized assessor-blinded clinical study. Healthy participants (age 18 to 40) were included and randomized. Participants in the intervention group were instructed to perform 2 stretching exercises targeting the calf muscles; 3 times 30 seconds, 7 days...... a week for 4 weeks on the dominant leg. Participants in the control group were instructed not to do any stretching for 4 weeks. Pressure pain threshold (PPT) and temporal summation (TS) of pressure pain were measured on the stretched calf, the contra-lateral calf, and contra-lateral lower arm using...

  4. Efficacy and safety of maraviroc versus efavirenz, both with zidovudine/lamivudine: 96-week results from the MERIT study.

    Science.gov (United States)

    Sierra-Madero, Juan; Di Perri, Giovanni; Wood, Robin; Saag, Michael; Frank, Ian; Craig, Charles; Burnside, Robert; McCracken, Jennifer; Pontani, Dennis; Goodrich, James; Heera, Jayvant; Mayer, Howard

    2010-01-01

    The MERIT study evaluated maraviroc versus efavirenz, both with zidovudine/lamivudine, in treatment-naïve patients with CCR5-tropic (R5) HIV-1. Post hoc analyses previously assessed week 48 outcomes in patients rescreened with R5 virus by a more sensitive tropism assay. Week 96 efficacy (post hoc, n = 614) and safety (n = 721) were assessed. Proportions of subjects <50 copies/mL (58.8% maraviroc, 62.7% efavirenz) and time to loss of virologic response (TLOVR) responders (<50 copies/mL: 60.5% vs 60.7%) were similar. Maraviroc recipients had greater CD4 increases (+ 212 vs + 171 cells/mm(3)) and fewer adverse event discontinuations (6.1% vs 15.5%), malignancies, and category C events. Week 96 data confirm week 48 observations in MERIT.

  5. One-week triple therapy for eradication of helicobacter pylori

    International Nuclear Information System (INIS)

    Shah, N.H.; Shah, M.S.; Khan, I.; Hameed, K.

    2002-01-01

    Objective: The optimum therapy for Helicobacter pylori infection is yet to be defined in Pakistan despite a high prevalence of helicobacter associated diseases in this community. The most popular and effective regimen was therefore chosen among the currently recommended combinations used worldwide to document its efficacy in our symptomatic Helicobacter positive dyspeptic patients. Design: It was a prospective, non-randomized study. Place and duration of Study: The study lasted from January 1998 till June 1999 at the Postgraduate Institute, Government Lady Reading Hospital and Fauji Foundation Hospital, Peshawar. Subjects and Methods: Consecutive dyspeptic patients with peptic ulcer disease as well as non ulcer dyspepsia with a positive H. pylori status on histology from the specimens obtained from the antral region of the stomach, who consented to take part in the study were enrolled. They were given omeprazole 20 mg bd, clarithromycin 500 mg bd. And amoxycillin 1 gm bd for one week. One group comprised patients with confirmed peptic ulcer disease while the second group comprised patients with macroscopic/microscopic antral gastritis. Patients with peptic ulcer disease were given additional course of omerprazol for another 4 weeks to ensure healing of their ulcers. All patients were re scoped after stopping all drugs and their H. pylori status re-assessed on histology. Results: A total of 84 patients consented to enter the study. Fifty-nine were males and twenty-five were females. Fifty-eight patients completed the study while others were lost followup. There were no dropouts due to side effects of the drugs. Sixteen patients had peptic ulcer disease while 68 had macroscopic/microscopic active antral gastric only. The Helicobacter pylori eradication has been successful in only 12 patients giving a cure rate of 20.60% as determined per protocol analysis. The eradication rates were disappointingly low in both groups. Conclusion: The results are extremely

  6. Results of a 5-Week Schedule of Modern Total Skin Electron Beam Radiation Therapy

    Energy Technology Data Exchange (ETDEWEB)

    Morris, Stephen Lloyd, E-mail: stephen.morris@gstt.nhs.uk [St Johns Institute of Dermatology, Guys and St Thomas Hospital, London (United Kingdom); McGovern, Mark; Bayne, Sally; Wain, Mary; Child, Fiona; Whittaker, Sean [St Johns Institute of Dermatology, Guys and St Thomas Hospital, London (United Kingdom)

    2013-08-01

    Purpose: To report the outcomes of a 5-week schedule of total skin electron beam radiation therapy (TSEB) for mycosis fungoides (MF). Methods: Over 5 years, 41 patients with confirmed MF were treated with a modern TSEB technique delivering 30 Gy in 20 fractions over 5 weeks to the whole skin surface. Data were collected prospectively and entered into the skin tumor unit research database. Skin modified skin weighted assessment tool score data were collected to determine response, duration of response, survival, and toxicity. The outcomes were analyzed according to the patient's stage before TSEB, prognostic factors, and adjuvant treatments. Results: Seventeen patients were stage 1B, 19 were stage IIB, 3 were stage III, and 2 were stage IV. The overall response rate was 95%, with a complete response rate of 51%. Seventy-six percent of patients had relapsed at median follow-up of 18 months. The median time to relapse was 12 months, to systemic therapy was 15 months, and to modified skin weighted assessment tool progression above baseline was 44 months. The complete response rate was 59% in stage IB and 47% in stage IIB patients. The median time to skin relapse was longer in stage IB compared with stage IIB, 18 months versus 9 months. The median time to systemic therapy was longer in stage IB compared with stage IIB, >56 months versus 8 months. The median overall survival was 35 months: >56 months for stage IB, 25 months for stage IIB, 46 months for stage III, and 23.5 months for stage IV. Fifteen patients received adjuvant psoralen + ultraviolet A treatment with no difference seen in the time to relapse. Conclusions: This 5-week schedule of TSEB for MF has a high response rate with comparable duration of response to other regimens. Future studies are needed to find adjuvant and combination treatments to improve the duration of response.

  7. Teaching Co-Design Games in Five Weeks

    DEFF Research Database (Denmark)

    Brandt, Eva; Kjærgård, Sarasiff; Risak Schou, Gudrun

    2011-01-01

    This paper is about educating designers as codesigners and reflective practitioners. It is argued that an important goal in design pedagogy is learning the students’ strategies and tools for how to involve various stakeholders in designing, and how to deal with uncertainty and open design agendas....... It is important in order to prepare students for a career as designers. The paper reports from an intense five weeks course about developing and using design games as a frame for design-oriented collaborations with people outside the core design team. Co-design is about making room for people with diverse...... interests, roles and responsibilities in rehearsing the future. Using the game metaphor to stage and engage everyone is a valuable format for collaborative inquiry and co-creating future visions – in other words exploring diversity and creating unity about values and goals. The professional designer...

  8. The last ATLAS overview week now available on Web Lectures

    CERN Multimedia

    Jeremy Herr

    2006-01-01

    As reported in the September 2004 ATLAS eNews, the Web Lecture Archive Project, WLAP, a collaboration between the University of Michigan and CERN, has developed a synchronized system for recording and publishing educational multimedia presentations, using the Web as medium. This year, the University of Michigan team has been asked to record and publish all ATLAS Plenary sessions, as well as a large number of Physics and Computing tutorials. A significant amount of this material has already been published and can be accessed via the links below. All lectures can be viewed on any major platform with any common internet browser, either via streaming or local download (for limited bandwidth). Please enjoy the lectures and send us a note at wlap@umich.edu to tell us what you think. The newly available WLAP items relating to ATLAS is the following: ATLAS Week Plenary, CERN, 2-3 October 2006 All previous WLAP lectures are also avilable on the web.

  9. Reversible metronidazole-induced neurotoxicity after 10 weeks of therapy.

    Science.gov (United States)

    AlDhaleei, Wafa; AlMarzooqi, Ayesha; Gaber, Nouran

    2018-04-20

    Metronidazole is a commonly used antimicrobial worldwide. The most common side effects that have been reported are nausea, vomiting and hypersensitivity reactions. However, neurotoxicity has been reported with the use of metronidazole but rather rare. The most common neurological manifestation is peripheral neuropathy involvement in the form of sensory loss. It is worth mentioning that central neurotoxicity is a rare side effect of metronidazole use but reversible. The manifestations vary from a headache, altered mental status to focal neurological deficits. The diagnosis is mainly by neuroimaging in the setting of acute neurological change in the patient status. Here, we report a case of metronidazole-induced neurotoxicity in a 38-year-old male patient who was admitted with a brain abscess and was started on metronidazole for more than 10 weeks. © BMJ Publishing Group Ltd (unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  10. Italian singer Annalisa at CERN for a week of filming

    CERN Multimedia

    Stefania Pandolfi

    2015-01-01

    CERN welcomed Italian singer-songwriter Annalisa for a week-long visit to the Laboratory to shoot an Italian television production about the Laboratory.   Annalisa in the CERN Control Centre.   The Italian artist has a degree in physics from the University of Turin, Italy. She is a singer and songwriter, famous for her successful participation in the Italian talent show, Amici di Maria De Filippi. She has recorded four albums as solo artist and has participated twice in the Sanremo Music Festival, the most important Italian song contest. She has also received numerous Italian music awards, and has earned international recognition. Thanks to her knowledge of physics and her great influence with the Italian youth, Annalisa was selected to host an Italian television production about CERN aimed at young people. 

  11. Medical image of the week: central pontine myelinolysis

    Directory of Open Access Journals (Sweden)

    Siddiqi TA

    2014-01-01

    Full Text Available A 38-year-old woman with history of alcohol abuse was admitted with generalized weakness, dehydration, alcoholic hepatitis, hyponatremia (serum sodium 116 mM/L, and cachexia (BMI 19 kg/m2. She developed hypoxemic respiratory failure after intravenous fluid resuscitation and required intubation and mechanical ventilation. Neurological exam revealed motor weakness, hyporeflexia, ataxia, and unsustained clonus. Neurology consultation was obtained and MRI revealed hyperintensity in the pons consistent with osmotic demyelination syndrome (1. Review of her records revealed her sodium level increased by 8 mM/L in first 6 hours of presentation, and then a slow increase of 4-6 mM/L daily to the normal range. She received nutritional support and aggressive physical therapy, and was discharged to skilled nursing facility after six weeks of hospitalization.

  12. The Occurrence of the Day-of-the-Week Effects on Polish and Major World Stock Markets

    Directory of Open Access Journals (Sweden)

    Jamróz Paweł

    2014-08-01

    Full Text Available The aim of this paper is to analyze the occurrence of the so called day of the week effects in market return time series from the period of January 2003 to September 2013 (and additionally January 1999 to December 2002. The study focuses on four indices of the Warsaw Stock Exchange (WIG, WIG20, mWIG40 and sWIG80 and additionally five indices of major world stock exchanges (NIKKEI 225, DAX, CAC40, S&P 500, and IBEX. The main data sample was divided into three subperiods in order to determine whether or not the intensity of day of the week anomalies is constant in time. The study revealed a substantial number of the day of the week anomalies in earliest subperiods and very limited evidence of those effects in later ones, giving rise to the conclusion that the intensity of the day of the week anomalies is diminishing with time. The most common effect identified on the WSE was a positive Friday effect. The Monday effect often described in early literature on the subject matter seems to currently occur very rarely. The study also indicates that the day of the week effects were more persistent among stocks with smaller market capitalization on the WSE.

  13. Randomised preference trial of medical versus surgical termination of pregnancy less than 14 weeks' gestation (TOPS).

    Science.gov (United States)

    Robson, S C; Kelly, T; Howel, D; Deverill, M; Hewison, J; Lie, M L S; Stamp, E; Armstrong, N; May, C R

    2009-11-01

    were lower after MTOP in both randomised and preference arms. During admission women undergoing MTOP had more symptoms and reported higher mean pain scores, and after discharge reported more nausea and diarrhoea. There were no differences in time taken to return to work between groups; around 90% had returned to work and normal activity by 2 weeks. Rates of unplanned or emergency admissions were higher after MTOP than after STOP. Overall complication rates were also higher after MTOP, although this only achieved statistical significance in the preference arm. Overall, STOP cost more than MTOP due to higher inpatient standard costs. Even though complication rates were higher with MTOP, it was still more cost-effective. DCE identified three attributes with an almost equal impact on women's preferences: provision of counselling, number of days delay to the procedure, and possibility of an overnight stay. MTOP was associated with more negative experiences of care and lower acceptability. Acceptability of MTOP declined with increasing gestational age. MTOP was less costly but also less effective than STOP. The majority of women choosing MTOP were satisfied with their care and found the procedure acceptable. RECOMMENDATIONS FOR FURTHER RESEARCH: An audit of provision of MTOP and STOP in England and Wales is urgently required. Further studies exploring the barriers to offering women the choice of method of TOP are needed, together with research on the acceptability and effectiveness of (1) MTOP and manual VA in pregnancies below 9 weeks' gestation and (2) MTOP and dilatation and evacuation after 14 weeks' gestation. Current Controlled Trials ISRCTN07823656.

  14. Profile of weekly training load in elite male professional basketball players.

    Science.gov (United States)

    Manzi, Vincenzo; D'Ottavio, Stefano; Impellizzeri, Franco M; Chaouachi, Anis; Chamari, Karim; Castagna, Carlo

    2010-05-01

    The aim of this study was to examine the training load (TL) profile of professional elite level basketball players during the crucial parts of the competitive season (pre-play-off finals). Subjects were 8 full-time professional basketball players (age 28 +/- 3.6 years, height 199 +/-7.2 cm, body mass 102 +/- 11.5 kg, and body fat 10.4 +/- 1.5%) whose heart rate (HR) was recorded during each training session and their individual response to TL monitored using the session-rate of perceived exertion (RPE) method (200 training sessions). The association between the session-RPE method and training HR was used to assess the population validity of the session-RPE method. Significant relationships were observed between individual session-RPE and all individual HR-based TL (r values from 0.69 to 0.85; p 0.05). Elite male professional basketball imposes great physiological and psychological stress on players through training sessions and official competitions (1-2 per week). Consequently, the importance of a practical and valid method to assess individual TL is warranted. In this research, we demonstrated that session-RPE may be considered as a viable method to asses TL without the use of more sophisticated tools (i.e., HR monitors). The session-RPE method enabled the detection of periodization patterns in weekly planning in elite professional basketball during the crucial part of the competitive season (1 vs. 2 weekly fixtures model).

  15. Early preeclampsia and HELLP syndrome in a 20 week pregnant patient

    Directory of Open Access Journals (Sweden)

    Fatemeh Keighobadi Khajeh

    2017-01-01

    Full Text Available The first time Weinstein in 1982 described patients with the syndrome of hemolysis, elevated liver enzymes, and low platelet count (HELLP in pregnant preeclamptic and eclamptic patients. This syndrome is a severe form of preeclampsia or eclampsia. Usually HELLP syndrome occurs at the third trimester and only 15% occur before the 27th week of pregnancy and rarely before the 20th week of pregnancy. We want to present a 30- year old parity 2, gravidity 1 pregnant patient who was pregnant for 20 weeks with preeclampsia and HELLP syndrome. Two hours before arriving to the emergency unit, she felt chest discomfort and went to the nearest clinic to visit a physician. She was then referred to the hospital because of high blood pressure (BP. When she arrived to the emergency unit, she had right upper quadrant and epigastric pain, headache, vomiting, dyspnea, and high BP (185/100. Finally the diagnosis of HELLP syndrome was made. As maternal and fetus mortality and morbidity of HELLP syndrome is high, immediate recognition and treatment is vital to save the lives of both the mother and the fetus

  16. To What Extent Can Adolescent Scoliosis Be Improved in Four Weeks?

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    Mehmet Ağırman

    2016-03-01

    Full Text Available Scoliosis is a condition that leads to severe disability and an impaired cosmetic appearance in adolescence. This article presents x-ray images of a patient with adolescent idiopathic scoliosis (AIS in whom the pain and posture improved dramatically over four weeks, emphasizing the importance of physical therapy. A 13-year-old male was admitted because of posture deformity and mild back and lower back pain. He was being followed with the diagnosis of scoliosis for two years and specific exercises were proposed for scoliosis. On physical examination, we observed paravertebral muscle spasm and significant asymmetry of the thoracolumbar region. Neurological examination and laboratory tests were normal. X-ray showed arcuate thoracolumbar scoliosis (cobb angle: 24° with a leftward convexity. Electrical stimulation was applied to the convex and concave sides for 30 minutes, five times a week for four weeks and an exercise program was performed under the supervision of a therapist. The stimulation amplitude was the maximum stimulation intensity with which the patient was comfortable. Analgesic and myorelaxant drugs were not required, and no brace was used. After the treatment, significant improvements were observed in the patient’s posture and radiography (cobb angle: 10°. This work demonstrates that well-planned physical therapy is a rapid and effective option for treating AIS.

  17. The ATLAS Overview Week at Clermont-Ferrand, June 23-28, 2002

    CERN Multimedia

    Smith, K.

    Those of us who travelled on Saturday from CERN to the ATLAS Week in Clermont- Ferrand had an unusually long journey because of autoroute problems around Nantua, but arrived with a bang as a spectacular fireworks display lit up the local volcano in (simulated!) eruption. The Overview Week, which followed on from similarly successful Overview Weeks in Dubna and Brookhaven, was organised superbly by François Vazeille and members of the local ATLAS group, (who are more usually completely engrossed in construction of electronics etc. for the Tile Calorimeter). It began with an extremely warm welcome in more ways than one, since the temperature on Sunday reached a thirty-five year maximum of around thirty-seven degrees and made the initial sessions on Installation, DIG and some physics groups a bit hard on those of us from the cold Northern regions!! The local team had prepared a full agenda, both on the physics and on the social side, but allowed ample time for the informal discussions which are an essenti...

  18. How many days of accelerometer monitoring predict weekly physical activity behaviour in obese youth?

    Science.gov (United States)

    Vanhelst, Jérémy; Fardy, Paul S; Duhamel, Alain; Béghin, Laurent

    2014-09-01

    The aim of this study was to determine the type and the number of accelerometer monitoring days needed to predict weekly sedentary behaviour and physical activity in obese youth. Fifty-three obese youth wore a triaxial accelerometer for 7 days to measure physical activity in free-living conditions. Analyses of variance for repeated measures, Intraclass coefficient (ICC) and regression linear analyses were used. Obese youth spent significantly less time in physical activity on weekends or free days compared with school days. ICC analyses indicated a minimum of 2 days is needed to estimate physical activity behaviour. ICC were 0·80 between weekly physical activity and weekdays and 0·92 between physical activity and weekend days. The model has to include a weekday and a weekend day. Using any combination of one weekday and one weekend day, the percentage of variance explained is >90%. Results indicate that 2 days of monitoring are needed to estimate the weekly physical activity behaviour in obese youth with an accelerometer. Our results also showed the importance of taking into consideration school day versus free day and weekday versus weekend day in assessing physical activity in obese youth. © 2013 Scandinavian Society of Clinical Physiology and Nuclear Medicine. Published by John Wiley & Sons Ltd.

  19. Interpreting the Impact of the Four-Day School Week: An Examination of Performance before and after Switching to the Four-Day School Week

    Science.gov (United States)

    Gower, Matthew Lee

    2017-01-01

    As four-day school weeks continue to gain popularity among school districts across the United States, determining the potential impact associated with the unconventional school week has become increasingly important (Johnson, 2013). The four-day school week has been credited with producing a number of potential benefits and consequences, but there…

  20. Antibiotic treatment for 6 weeks versus 12 weeks in patients with pyogenic vertebral osteomyelitis: an open-label, non-inferiority, randomised, controlled trial.

    Science.gov (United States)

    Bernard, Louis; Dinh, Aurélien; Ghout, Idir; Simo, David; Zeller, Valerie; Issartel, Bertrand; Le Moing, Vincent; Belmatoug, Nadia; Lesprit, Philippe; Bru, Jean-Pierre; Therby, Audrey; Bouhour, Damien; Dénes, Eric; Debard, Alexa; Chirouze, Catherine; Fèvre, Karine; Dupon, Michel; Aegerter, Philippe; Mulleman, Denis

    2015-03-07

    Duration of treatment for patients with vertebral osteomyelitis is mainly based on expert recommendation rather than evidence. We aimed to establish whether 6 weeks of antibiotic treatment is non-inferior to 12 weeks in patients with pyogenic vertebral osteomyelitis. In this open-label, non-inferiority, randomised controlled trial, we enrolled patients aged 18 years or older with microbiologically confirmed pyogenic vertebral osteomyelitis and typical radiological features from 71 medical care centres across France. Patients were randomly assigned to either 6 weeks or 12 weeks of antibiotic treatment (physician's choice in accordance with French guidelines) by a computer-generated randomisation list of permuted blocks, stratified by centre. The primary endpoint was the proportion of patients who were classified as cured at 1 year by a masked independent validation committee, analysed by intention to treat. Non-inferiority would be declared if the proportion of cured patients assigned to 6 weeks of treatment was not less than the proportion of cured patients assigned to 12 weeks of treatment, within statistical variability, by an absolute margin of 10%. This trial is registered with EudraCT, number 2006-000951-18, and Clinical Trials.gov, number NCT00764114. Between Nov 15, 2006, and March 15, 2011, 359 patients were randomly assigned, of whom six in the 6-week group and two in the 12-week group were excluded after randomisation. 176 patients assigned to the 6-week treatment regimen and 175 to the 12-week treatment regimen were analysed by intention to treat. 160 (90·9%) of 176 patients in the 6-week group and 159 (90·9%) of 175 of those in the 12-week group met the criteria for clinical cure. The difference between the groups (0·05%, 95% CI -6·2 to 6·3) showed the non-inferiority of the 6-week regimen when compared with the 12-week regimen. 50 patients in the 6-week group and 51 in the 12-week group had adverse events, the most common being death (14 [8%] in

  1. Effects of four weeks of repeated sprint training on physiological indices in futsal players

    Directory of Open Access Journals (Sweden)

    Paulo Cesar do Nascimento

    2014-12-01

    Full Text Available DOI: http://dx.doi.org/10.5007/1980-0037.2015v17n1p91   The aim of this study was to investigate the effects of short repeated-sprint ability (RSA training on the neuromuscular and physiological indices in U17 futsal players during the competitive period. Fourteen players were divided into two groups: intervention group (n = 8 and control group (n = 6. Both groups performed a repeated maximal sprint test (40-m MST, intermittent shuttle-running test (Carminatti’s test and vertical jumps before and after the training period. The intervention group was submitted to an additional four-week repeated sprints program, twice a week, while the control group maintained their normal training routine. There was no significant interaction between time and groups for all variables analysed (p > 0.05. However, a significant main effect was observed for time (p < 0.01 indicating an increase on speed at heart rate deflection point (VHRDP and the continuous jump performance while the peak lactate (40m-LACpeak and sprint decrement decreased after training, in both groups. Still, based on effect sizes (ES the greater changes with practical relevance were verified for intervention group in important variables such as peak velocity (ES = 0,71, VHRDP (ES = 0,83 and 40m-LACpeak (ES = 1,00. This study showed that RSA-based and normal training routine are equally effective in producing changes in the analysed variables during a short period of intervention. However, the effect size suggests that four weeks of RSA training would be a minimum time that could induce the first changes of futsal player’s physical fitness.

  2. Thirteen week toxicity study of dietary l-tryptophan in rats with a recovery period of 5 weeks.

    Science.gov (United States)

    Shibui, Yusuke; Matsumoto, Hideki; Masuzawa, Yoko; Ohishi, Takumi; Fukuwatari, Tsutomu; Shibata, Katsumi; Sakai, Ryosei

    2018-04-01

    Although l-tryptophan is nutritionally important and widely used in medical applications, toxicity data for its oral administration are limited. The purpose of this study was to evaluate the potential toxicity of an experimental diet containing added l-tryptophan at doses of 0 (basal diet), 1.25%, 2.5% and 5.0% when administered to Sprague-Dawley rats for 13 weeks. There were no toxicological changes in clinical signs, ophthalmology, urinalysis, hematology, necropsy, organ weight and histopathology between control rats and those fed additional l-tryptophan. Body weight gain and food consumption significantly decreased throughout the administration period in males in the 2.5% group and in both sexes in the 5.0% group. At the end of the dosing period, decreases in water intake in males in the 5.0% group and in serum glucose in females in the 5.0% group were observed. The changes described above were considered toxicologically significant; however, they were not observed after a 5 week recovery period, suggesting reversibility. Consequently, the no-observed-adverse-effect level of l-tryptophan in the present study was 1.25% for males and 2.5% for females (mean intake of l-tryptophan: 779 mg kg -1 body weight day -1 [males] and 1765 mg kg -1 body weight day -1 [females]). As the basal diet used in this study contained 0.27% of proteinaceous l-tryptophan, the no-observed-adverse-effect level of overall l-tryptophan was 1.52% for males and 2.77% for females (mean intake of overall l-tryptophan: 948 mg kg -1 body weight day -1 (males) and 1956 mg kg -1 body weight day -1 (females)). We conclude that l-tryptophan has a low toxicity profile in terms of human use. Copyright © 2017 John Wiley & Sons, Ltd.

  3. Straight to flexible sigmoidoscopy: rationalization of 2-week wait referrals in suspected colorectal cancer.

    Science.gov (United States)

    Couch, D G; Murphy, J H; Boyle, K M; Hemingway, D M

    2015-11-01

    The 2-week wait pathway was designed to decrease the time from presentation to primary care of patients with 'red flag' symptoms of suspected cancer for review by a specialist for the diagnosis or exclusion of cancer. In our tertiary referral centre we have found that 968 colonoscopies per year are required to satisfy the demand for the 2-week wait, leading to limited colonoscopy availability for other services. We sought to determine the yield of colorectal cancer found at colonoscopy referred via the 2-week wait and referenced to the original red flag symptoms. This was in order to select the most efficacious alternative primary investigation based upon presenting symptoms. Electronic records were retrospectively analysed. All patients who went through the 2-week wait for suspicion of colorectal cancer in 2013 and were found to have colorectal cancer on colonoscopy were included. Patients not undergoing colonoscopy as the first investigation were excluded. The splenic flexure was deemed to be within the range of a flexible sigmoidoscope. In all, 2950 referrals were made. 968 colonoscopies were performed as the primary investigation of which 35 were found to have colorectal cancer. No patients referred with rectal bleeding and another symptom had a tumour more proximal to the range of flexible sigmoidoscopy. 80% of tumours proximal to the splenic flexure were suitable for CT diagnosis alone. Our data support the use of flexible sigmoidoscopy alone as an initial investigation for patients presenting with rectal bleeding with or without additional colorectal symptoms. Patients with anaemia (without bleeding) or change in bowel habit (without bleeding) may be investigated with CT colonography alone; colonoscopy may then be used selectively prior to surgery. Colorectal Disease © 2015 The Association of Coloproctology of Great Britain and Ireland.

  4. Health state utilities associated with attributes of weekly injection devices for treatment of type 2 diabetes

    Directory of Open Access Journals (Sweden)

    Louis S. Matza

    2017-11-01

    Full Text Available Abstract Background Glucagon-like peptide-1 (GLP-1 receptor agonists are often recommended as part of combination therapy for type 2 diabetes when oral medication does not result in sufficient glycemic control. Several GLP-1 receptor agonists are available as weekly injections. These medications vary in their injection delivery systems, and these differences could impact quality of life and treatment preference. The purpose of this study was to estimate utilities associated with attributes of injection delivery systems for weekly GLP-1 therapies. Methods Participants with type 2 diabetes in the UK valued health states in time trade-off interviews. The health states (drafted based on literature, device instructions for use, and clinician interviews had identical descriptions of type 2 diabetes, but differed in description of the treatment process. One health state described oral treatment, while six others described oral treatment plus a weekly injection. The injection health states varied in three aspects of the treatment administration process: requirements for reconstituting the medication (i.e., mixing the medication prior to the injection, waiting during medication preparation, and needle handling. Every participant valued all seven health states. Results A total of 209 participants completed interviews (57.4% male; mean age = 60.4y. The mean utility of the oral treatment health state was 0.89. All injection health states had significantly (p < 0.01 lower utilities ranging from 0.86 to 0.88. Differences among health state utilities suggest that each administration requirement had a small but measureable disutility: -0.004 (reconstitution, -0.004 (needle handling, -0.010 (reconstitution, needle handling, and -0.020 (reconstitution, waiting, needle handling. Conclusions Findings suggest it is feasible to use the TTO method to quantify preferences among injection treatment processes. It may be useful to incorporate these utility differences

  5. Analyzing repeated data collected by mobile phones and frequent text messages. An example of Low back pain measured weekly for 18 weeks

    Directory of Open Access Journals (Sweden)

    Axén Iben

    2012-07-01

    Full Text Available Abstract Background Repeated data collection is desirable when monitoring fluctuating conditions. Mobile phones can be used to gather such data from large groups of respondents by sending and receiving frequently repeated short questions and answers as text messages. The analysis of repeated data involves some challenges. Vital issues to consider are the within-subject correlation, the between measurement occasion correlation and the presence of missing values. The overall aim of this commentary is to describe different methods of analyzing repeated data. It is meant to give an overview for the clinical researcher in order for complex outcome measures to be interpreted in a clinically meaningful way. Methods A model data set was formed using data from two clinical studies, where patients with low back pain were followed with weekly text messages for 18 weeks. Different research questions and analytic approaches were illustrated and discussed, as well as the handling of missing data. In the applications the weekly outcome “number of days with pain” was analyzed in relation to the patients’ “previous duration of pain” (categorized as more or less than 30 days in the previous year. Research questions with appropriate analytical methods 1: How many days with pain do patients experience? This question was answered with data summaries. 2: What is the proportion of participants “recovered” at a specific time point? This question was answered using logistic regression analysis. 3: What is the time to recovery? This question was answered using survival analysis, illustrated in Kaplan-Meier curves, Proportional Hazard regression analyses and spline regression analyses. 4: How is the repeatedly measured data associated with baseline (predictor variables? This question was answered using generalized Estimating Equations, Poisson regression and Mixed linear models analyses. 5: Are there subgroups of patients with similar courses of pain

  6. Effects of 12-week supervised treadmill training on spatio-temporal gait parameters in patients with claudication.

    Science.gov (United States)

    Konik, Anita; Kuklewicz, Stanisław; Rosłoniec, Ewelina; Zając, Marcin; Spannbauer, Anna; Nowobilski, Roman; Mika, Piotr

    2016-01-01

    The purpose of the study was to evaluate selected temporal and spatial gait parameters in patients with intermittent claudication after completion of 12-week supervised treadmill walking training. The study included 36 patients (26 males and 10 females) aged: mean 64 (SD 7.7) with intermittent claudication. All patients were tested on treadmill (Gait Trainer, Biodex). Before the programme and after its completion, the following gait biomechanical parameters were tested: step length (cm), step cycle (cycle/s), leg support time (%), coefficient of step variation (%) as well as pain-free walking time (PFWT) and maximal walking time (MWT) were measured. Training was conducted in accordance with the current TASC II guidelines. After 12 weeks of training, patients showed significant change in gait biomechanics consisting in decreased frequency of step cycle (p gait was more regular, which was expressed via statistically significant decrease of coefficient of variation (p 0.05). Twelve-week treadmill walking training programme may lead to significant improvement of temporal and spatial gait parameters in patients with intermittent claudication. Twelve-week treadmill walking training programme may lead to significant improvement of pain-free walking time and maximum walking time in patients with intermittent claudication.

  7. THE EFFECTS OF A 6-WEEK PLYOMETRIC TRAINING PROGRAM ON AGILITY

    Directory of Open Access Journals (Sweden)

    Michael G. Miller

    2006-09-01

    Full Text Available The purpose of the study was to determine if six weeks of plyometric training can improve an athlete's agility. Subjects were divided into two groups, a plyometric training and a control group. The plyometric training group performed in a six week plyometric training program and the control group did not perform any plyometric training techniques. All subjects participated in two agility tests: T-test and Illinois Agility Test, and a force plate test for ground reaction times both pre and post testing. Univariate ANCOVAs were conducted to analyze the change scores (post - pre in the independent variables by group (training or control with pre scores as covariates. The Univariate ANCOVA revealed a significant group effect F2,26 = 25.42, p=0.0000 for the T-test agility measure. For the Illinois Agility test, a significant group effect F2,26 = 27.24, p = 0.000 was also found. The plyometric training group had quicker posttest times compared to the control group for the agility tests. A significant group effect F2,26 = 7.81, p = 0.002 was found for the Force Plate test. The plyometric training group reduced time on the ground on the posttest compared to the control group. The results of this study show that plyometric training can be an effective training technique to improve an athlete's agility

  8. One Year Sustain ability of Risk Factor Change from a 9-Week Workplace Intervention

    International Nuclear Information System (INIS)

    Rush, E.C.; Cumin, M.B.; Migriauli, L.; Ferguson, L.R.; Plank, L.D.

    2010-01-01

    We examined the effect of a 9-week diet and physical activity intervention provided in the workplace by a group education session where personal dietary and physical activity goals were proposed. Measurements of anthropometry, fasting blood lipids, glucose and insulin, assays for antioxidant activity (AOA) and questionnaires were completed at 0, 3, 6, 9, and 12 weeks in 50 healthy workers (50% male, mean age 46y). Followup measurements in 39 (56% male) were possible at 52 weeks. At week 3 a group dietary and physical activity motivational seminar was held. At week 6, half the group were supplied daily kiwifruit for 3 weeks with cross over at week 9 until week 12. Compared to baseline, lipid, glucose, insulin and AOA measurements were improved at 12 and 52 weeks. Body measurements did not change. Group diet and physical activity advice reinforced over 9 weeks is associated with a sustained improvement in cardiovascular risk factors at 52 weeks.

  9. One Year Sustainability of Risk Factor Change from a 9-Week Workplace Intervention

    Science.gov (United States)

    Rush, Elaine C.; Cumin, Michelle B.; Migriauli, Lela; Ferguson, Lynnette R.; Plank, Lindsay D.

    2009-01-01

    We examined the effect of a 9-week diet and physical activity intervention provided in the workplace by a group education session where personal dietary and physical activity goals were proposed. Measurements of anthropometry, fasting blood lipids, glucose and insulin, assays for antioxidant activity (AOA) and questionnaires were completed at 0, 3, 6, 9, and 12 weeks in 50 healthy workers (50% male, mean age 46y). Followup measurements in 39 (56% male) were possible at 52 weeks. At week 3 a group dietary and physical activity “motivational seminar” was held. At week 6, half the group were supplied daily kiwifruit for 3 weeks with cross over at week 9 until week 12. Compared to baseline, lipid, glucose, insulin and AOA measurements were improved at 12 and 52 weeks. Body measurements did not change. Group diet and physical activity advice reinforced over 9 weeks is associated with a sustained improvement in cardiovascular risk factors at 52 weeks. PMID:20169118

  10. One Year Sustainability of Risk Factor Change from a 9-Week Workplace Intervention

    Directory of Open Access Journals (Sweden)

    Elaine C. Rush

    2009-01-01

    Full Text Available We examined the effect of a 9-week diet and physical activity intervention provided in the workplace by a group education session where personal dietary and physical activity goals were proposed. Measurements of anthropometry, fasting blood lipids, glucose and insulin, assays for antioxidant activity (AOA and questionnaires were completed at 0, 3, 6, 9, and 12 weeks in 50 healthy workers (50% male, mean age 46y. Followup measurements in 39 (56% male were possible at 52 weeks. At week 3 a group dietary and physical activity “motivational seminar” was held. At week 6, half the group were supplied daily kiwifruit for 3 weeks with cross over at week 9 until week 12. Compared to baseline, lipid, glucose, insulin and AOA measurements were improved at 12 and 52 weeks. Body measurements did not change. Group diet and physical activity advice reinforced over 9 weeks is associated with a sustained improvement in cardiovascular risk factors at 52 weeks.

  11. Right ventricular perforation by a passive-fixation pacemaker lead two weeks after implantation

    Directory of Open Access Journals (Sweden)

    Azeem S. Sheikh, BSc, MBBS, FCPS, MRCP

    2014-12-01

    Full Text Available Myocardial perforation is a rare complication of permanent pacemaker implantation. While most of the perforations occur at the time of implantation or within the first 24 h, delayed myocardial perforations are very rare. The clinical course is extremely variable with some patients presenting completely asymptomatic, while others can develop cardiac tamponade and haemodynamic instability. We report an unusual case of a subacute ventricular perforation caused by a passive-fixation lead two weeks after implantation and we successfully managed to extract the lead under local anaesthesia, without the patient undergoing surgery, as recommended in the previously published reports.

  12. Time over time

    Directory of Open Access Journals (Sweden)

    Vicente Navarro, Eduardo

    2006-05-01

    Full Text Available The present essay is designed to be a general introduction to the philosophical problem of time from its very different forms and ways of approaching. In this sense, the article covers the problem from different perspectives and gives a brief account of the plurality and diversity of the time found in the different philosophical definitions, in the different layers of knowledge, in different periods and cultures and also in the different instruments used to measure time itself

  13. Weekly and holiday-related patterns of panic attacks in panic disorder: a population-based study.

    Science.gov (United States)

    Kao, Li-Ting; Xirasagar, Sudha; Chung, Kuo-Hsuan; Lin, Herng-Ching; Liu, Shih-Ping; Chung, Shiu-Dong

    2014-01-01

    While chronobiological studies have reported seasonal variation in panic attacks (PA) episodes, information on the timing of PA by week-days may enable better understanding of the triggers of PA episodes and thereby provide pointers for suitable interventional approaches to minimize PA attacks. This study investigated weekly variation in potential PA admissions including associations with holidays using a population-based longitudinal, administrative claims-based dataset in an Asian population. This study used ambulatory care data from the "Longitudinal Health Insurance Database 2000. We identified 993 patients with panic disorder (PD), and they had 4228 emergency room (ER) admissions for potential PA in a 3-year period between 1 January 2009 and 31 December 2011. One-way analysis of variance (ANOVA) was used to examine associations between the potential PA admissions and holidays/weekend days/work-days of the week. The daily mean number of potential PA admissions was 3.96 (standard deviation 2.05). One-way ANOVA showed significant differences in potential PA admissions by holiday and day of the week (pholidays. Furthermore, the weekly variations were similar for females and males, although females always had higher potential PA admissions on both weekdays and holidays than the males. We found that potential PA admissions among persons with PD varied systematically by day of the week, with a significant peak on weekends and holidays.

  14. Response of Leptin and C-reactive Protein Serum Levels to 12 Weeks Moderate Intensity Aerobic Exercise in Obese Men

    Directory of Open Access Journals (Sweden)

    Sonia Ghiasi

    2017-01-01

    Full Text Available The aim of this study was to investigate the effect of 12 weeks moderate intensity aerobic exercise on leptin and C-reactive protein serum levels in obese men. The study was conducted in Urmia- Iran in 2015. Twenty-four obese men with an aged range 40-50 yrs. were enrolled into the study. Subjects were randomized to one of 2 groups exercise (n=12 and control groups (n=12. The exercise group performed aerobic exercise training up to 50-70 % heart rate reserve, three times a week for 12 weeks. Leptin and CRP serum level was measured by ELISA method before and after the 12 weeks. After 12 weeks exercise training, leptin and CRP serum level in the exercise group compared to the control group, were decreased significantly (P<0.05. To sum up, 12 weeks moderate intensity aerobic exercise in the reduction of CRP and leptin concentration had a prominent role that might be effective in reducing weight and improving cardiovascular risk factors.

  15. Neck Pain One Week after Pacemaker Generator Replacement.

    Science.gov (United States)

    Graham, Ross F; Wightman, John M

    2015-07-01

    The incidence of cardiac pacemaker implantation has risen markedly in the past three decades, making awareness of possible postprocedural complications critical to the emergency physician. This case is the first documented instance of internal jugular (IJ) deep vein thrombosis (DVT) from an uncomplicated pacemaker generator replacement. A patient presented to an Emergency Department with a 2-day history of mild left temporal headache migrating to his left neck. The patient did not volunteer this information, but review of systems revealed a temporary transvenous pacemaker inserted through the right IJ vein 1 week previously during a routine exchange of a left-sided cardiac pacemaker generator. Manipulation of the existing pacemaker wires entering the left subclavian vein was minimal. Computed tomographic angiography of the neck demonstrated near-complete thrombotic occlusion of the entire length of his left IJ vein. This required hospital admission for observation and treatment with anticoagulation. WHY SHOULD AN EMERGENCY PHYSICIAN BE AWARE OF THIS?: DVT, with thrombotic extension into adjacent vessels anywhere along the course of pacemaker wires, should be considered by the emergency provider in the evaluation of head, neck, or upper extremity symptoms after recent or remote implantation or manipulation of a transvenous cardiac pacemaker, including generator replacement. Failure to identify and treat appropriately could result in significant morbidity and mortality from airway edema, septic thrombophlebitis, superior vena cava syndrome, superior sagittal sinus thrombosis, or pulmonary embolism. Published by Elsevier Inc.

  16. Medical Image of the week: left ventricular non-compaction

    Directory of Open Access Journals (Sweden)

    Khoubyari R

    2016-06-01

    Full Text Available No abstract available. Article truncated at 150 words. A 38-year-old woman with history of type 2 diabetes mellitus and hypertension presented to emergency department with worsening exertional dyspnea and orthopnea for the past 2-3 months. She also reported a 14 pound weight gain within the 2 weeks prior to presentation. She denied any prior history of cardiac or pulmonary disease. Also, there was no family history of heart disease. She denies any recent sick contacts, smoking, alcohol drinking, or substance abuse. Physical exam revealed jugular venous pressure of 10 cm H2O and significant bilateral lower extremity pitting edema. Chest x-ray showed an enlarged cardiac silhouette. Brain naturetic peptide (BNP was 2,917 pg/mL. A subsequent echocardiogram revealed a left ventricular (LV ejection fraction of 23% with severe global LV hypokinesia with moderate mitral regurgitation. Thyroid panel as well as iron panel were within normal range. Other laboratories were unremarkable. For the new onset systolic heart failure, a coronary angiography was ...

  17. Patient satisfaction with clinicians in colorectal 2-week wait clinics.

    Science.gov (United States)

    Cock, Karen; Kent, Bridie

    2017-03-23

    To determine if patient satisfaction is affected by the clinician (nurse or doctor), conducting the colorectal 2-week wait (2ww) clinics. A prospective non-randomised comparative cohort study of 339 consecutive patients (divided by blind allocation into nurse-led (n=216) and doctor-led (n=123) cohorts) conducted over a 3-month period. Patient satisfaction in both cohorts was assessed by an adapted version of the Grogan et al validated patient satisfaction questionnaire. The questionnaire was piloted first and was found to have high internal reliability (Cronbach's alpha=0.91). The study had a response rate of 78% (n=258/331) and overall satisfaction scores showed 85% (n=149/175) of patients in the nurse-led cohort and 65% (n=54/83) of patients in the doctor-led cohort strongly agreed that they were satisfied with the care they received. Mean overall satisfaction scores in the two cohorts revealed that the nurse-led cohort achieved significantly more 'strongly agree' responses than the doctor-led cohort (ppatient satisfaction was affected by the clinician conducting the 2ww clinic, in that the nurse-led cohort displayed significantly higher patient satisfaction. However, there are areas that merit further research.

  18. A 13-week research-based biochemistry laboratory curriculum.

    Science.gov (United States)

    Lefurgy, Scott T; Mundorff, Emily C

    2017-09-01

    Here, we present a 13-week research-based biochemistry laboratory curriculum designed to provide the students with the experience of engaging in original research while introducing foundational biochemistry laboratory techniques. The laboratory experience has been developed around the directed evolution of an enzyme chosen by the instructor, with mutations designed by the students. Ideal enzymes for this curriculum are able to be structurally modeled, solubly expressed, and monitored for activity by UV/Vis spectroscopy, and an example curriculum for haloalkane dehalogenase is given. Unique to this curriculum is a successful implementation of saturation mutagenesis and high-throughput screening of enzyme function, along with bioinformatics analysis, homology modeling, structural analysis, protein expression and purification, polyacrylamide gel electrophoresis, UV/Vis spectroscopy, and enzyme kinetics. Each of these techniques is carried out using a novel student-designed mutant library or enzyme variant unique to the lab team and, importantly, not described previously in the literature. Use of a well-established set of protocols promotes student data quality. Publication may result from the original student-generated hypotheses and data, either from the class as a whole or individual students that continue their independent projects upon course completion. © 2017 by The International Union of Biochemistry and Molecular Biology, 45(5):437-448, 2017. © 2017 The International Union of Biochemistry and Molecular Biology.

  19. A good week for global collaboration in particle physics

    CERN Multimedia

    2015-01-01

    This has been a good week for global collaboration in particle physics. On Wednesday, the CERN family grew by one Associate Member when we received official confirmation that the accession agreement signed last year had been ratified by the Turkish parliament, and on Thursday, we signed a new cooperation agreement with the US.   The signature of a new cooperation agreement between CERN and the US at the White House on Thursday, 7 May marks both a renewal of a long-standing friendship and a commitment to take the partnership further. Signed between CERN, the US Department of Energy and the US National Science Foundation, it is a framework agreement that paves the way for detailed accords on continued US participation in CERN’s scientific programme, and on European collaboration in projects hosted in the US, including prospective neutrino facilities. It is an agreement that is tacitly renewed every five years, unless one of the signatories signals a need to end or amend it. I am part...

  20. Coralline algae are global palaeothermometers with bi-weekly resolution

    Science.gov (United States)

    Kamenos, N. A.; Cusack, M.; Moore, P. G.

    2008-02-01

    High resolution palaeoclimate data are required for the Holocene to resolve differences recorded by current proxies. The pole to pole distribution of rhodoliths (coralline algae) with their annual and sub-annual calcite bands make these attractive candidates for such a role. These bands contain climate information in the form of elemental traces. In situ temperature (IST) was recorded at two rhodolith beds for 1.5 years. The concentrations of MgCO 3 and SrCO 3 (mol %) deposited in Lithothamion glaciale and Phymatolithon calcareum over this 18- month period were determined using electron and ion microprobes. Highly significant linear relationships exist between Mg, Sr and IST as well as sea surface temperature. Calibration between Mg concentration and IST was used to obtain a 2-year temperature profile from a subfossil rhodolith thallus indicating half the seasonal peak-to-peak temperature amplitude earlier during the Holocene than the present day. Both slow-growing species (<200 μm year -1) allowed sampling resolutions of 23 year -1 which is equivalent to 1 reading every 2 weeks. Sub-monthly Mg and Sr records in rhodoliths make them unique globally distributed palaeothermometers which may help refine regional climate histories during the Holocene.

  1. MR imaging of pontine infarction within 2 weeks after ictus

    Energy Technology Data Exchange (ETDEWEB)

    Uchino, Akira; Hata, Hirofumi; Ohno, Masato (Kyushu Rosai Hospital, Fukuoka (Japan))

    1991-08-01

    Magnetic resonance (MR) images of 10 patients with pontine infarction were reviewed. A total of 17 examinations were performed on a 1.5 Tesla high-field scanner (GE) within two weeks after ictus. The infarcted area was detected by MR as early as 20 hours after stroke in one case. However, MR images obtained in two cases three and nine hours after onset were unremarkable. It is therefore suggested that follow-up study should be performed when initial MR images within 20 hours postictus are normal. T{sub 1}-weighted images at four, nine and twelve days after ictus were interpreted as normal. In two of these three examinations, the infarcted areas were clearly demonstrated as hyperintense lesions on T{sub 2}-weighted images. In the other examination, however, an area of mildly increased signal intensity was seen on T{sub 2}-weighted images. This case suggests that the fogging effect is also observed on MR imaging and that a small pontine infarction may be overlooked during the subacute stage. Basilar artery occlusion was detected as an absence-of-flow void in three of the ten patients. In conclusion, MR imaging proved to be a relatively useful diagnostic modality for evaluating acute and subacute pontine infarction. (author).

  2. Detection of alkaptonuria in a 1-week-old infant.

    Science.gov (United States)

    Thalagahage, Krishan Nilantha Hewa; Jayaweera, Jayaweera Arachchige Asela Sampath; Kumbukgolla, Wikum Widuranga; Senavirathne, Indika

    2015-05-08

    Alkaptonuria is a rare disorder that results from an inherited deficiency of aromatic amino acid metabolism. Only 21% of the children under the age of 1 year having the disease are identified in clinics. We report a case of a 1-week-old child of a first-degree consanguineous couple with a symptom of frequent nappy staining. Analysis of urine showed a homogentisic acid concentration exceeding 200 mg/dL. The physical examination revealed that the child was healthy. The parents' watchfulness and the close attention paid to the child were the keys to the early detection of this rare disease. After identifying the disease, adequate follow-up of the patient is important to reduce further complications. Anti-inflammatory therapy and increasing the muscle strength by exercises such as swimming would be useful to restrict joint pains and immobilisation. A low protein diet also could be recommended; that fact is yet to be proven by clinical trials. 2015 BMJ Publishing Group Ltd.

  3. INTERNATIONAL BUSINESS WEEKS – FROM CHALLENGE TO OPPORTUNITY

    Directory of Open Access Journals (Sweden)

    CHALUPOVA, Martina

    2016-06-01

    Full Text Available Article aims to analyse impact of project activities called International Business Weeks (IBW on outgoing student mobilities at the College of Polytechnics Jihlava. The IBW network was established by University Paris 13 in France and Leuven University College in Belgium (now University College Leuven-Limbourg 17 years ago to encourage finance/business students to apply for international mobility. The network of European business colleges/universities now contains 15 universities or colleges, College of Polytechnics in Jihlava (CPJ joined it in 2008. The main goal of the paper is to evaluate the effect of IBW on Erasmus mobility at CPJ. Analysis of the data from CPJ information system shows that this impact has weakened gradually. The data also proved that the interest in IBW among CPJ students is stagnating. Partial goal of the article is to suggest solutions for the projects’ revitalization. One of the conclusions is that there is a need for qualitative research among the students about their motivations and obstacles of international mobility, with focus on the psychological profile of the students.

  4. Impressions from the ATLAS Overview Week in Stockholm

    CERN Document Server

    De Jong, P.; Gowdy, S.

    2006-01-01

    Paul de Jong: "What a very nice city Stockholm in the summer turned out to be! The architecture, the relaxed style of the city and its islands and bridges, the terraces with people out on the streets until late at night made this a special trip. We visited many cool and trendy places, unfortunately many of those places are probably now a lot less cool and trendy after visits of so many physicists in shorts and white socks in sandals. A big applause for the organizers for a fine meeting, and getting us into the Stockholm city hall and the superb Wasa museum. (left) The Golden room of Stockholm City Hall. (right) Muriel was not the only one in the room entertaining noble dreams during the reception in the Golden Room of the Stockholm City Hall... ATLAS is a monstrously complicated piece of apparatus. It will be very impressive when it is finished and works, but there are so many places where things can go wrong. If I must name a single highlight of the week: I found the technical coordination of t...

  5. Human placentation from nidation to 5 weeks of gestation. Part I: What do we know about formative placental development following implantation?

    DEFF Research Database (Denmark)

    James, J L; Carter, Anthony Michael; Chamley, L W

    2012-01-01

    limited for ethical reasons. In this review we discuss our current knowledge of early placental formation from the time of implantation at 3 weeks of gestation to approximately 5-6 weeks of gestation, encompassing both the significant anatomical findings derived from the unique specimens obtained...

  6. Neonatal and infant outcomes in twin gestations with preterm premature rupture of membranes at 24-31 weeks of gestation.

    Science.gov (United States)

    Mendez-Figueroa, Hector; Dahlke, Joshua D; Viteri, Oscar A; Chauhan, Suneet P; Rouse, Dwight J; Sibai, Baha M; Blackwell, Sean C

    2014-08-01

    To describe the perinatal and infant and early childhood morbidity associated with preterm premature rupture of membranes (PROM) in a cohort of twin pregnancies evaluated prospectively with neonatal follow-up to 2 years of age. This was a secondary analysis of a randomized controlled trial of magnesium sulfate for prevention of cerebral palsy. Inclusion criteria were twin gestation with preterm PROM diagnosed between 24 0/7 and 31 6/7 weeks of gestation and planned expectant management. Latency (time from membrane rupture to delivery) and perinatal outcomes were evaluated by gestational age at membrane rupture. Long-term neonatal outcomes were also analyzed. Among 151 women who met inclusion criteria, the median gestational age at preterm PROM was 28.1 weeks (range 24.1-31.6 weeks). Approximately one-third of women achieved a latency of at least 1 week. Gestational age at preterm PROM (odds ratio [OR] 0.75, 95% confidence interval [CI] 0.63-0.90 for each week after 24 weeks of gestation) and cervical dilation at admission (OR 0.66, 95% CI 0.49-0.90 for each centimeter of dilation) were inversely associated with a latency period of at least 1 week. There were no stillbirths (95% CI 0-1%), but the rate of neonatal mortality was 90 per 1,000 newborns (95% CI 57-112) with a 7.3% cerebral palsy rate among survivors (95% CI 4.4-10.3%). In twin pregnancies, preterm PROM from 24 to 31 weeks of gestation is associated with a neonatal mortality rate of 9.0% and an overall cerebral palsy rate of 7.3%. A longer latency period is associated with less advanced cervical dilation and later gestational age at PROM. LEVEL OF EVIEDENCE: II.

  7. 76 FR 30495 - National Safe Boating Week, 2011

    Science.gov (United States)

    2011-05-25

    ... precautions and sensible behavior when spending time on the water. Safe boating is responsible boating. Individuals can prepare for excursions by taking boating safety courses and filing float plans with family...

  8. 78 FR 32535 - National Hurricane Preparedness Week, 2013

    Science.gov (United States)

    2013-05-30

    ... supply kit with food, water, and medicine; taking time now to learn evacuation routes, and how workplaces... with the tide, families whose worlds were torn apart with the loss of a loved one. But in the aftermath...

  9. Breastfeeding, infant formula, and introduction to complementary foods - comparing data obtained by questionnaires and health visitors' reports to weekly short message service text messages

    DEFF Research Database (Denmark)

    Bruun, Signe; Buhl, Susanne; Husby, Steffen

    2017-01-01

    compared. DESIGN: The study population was part of the Odense Child Cohort. The four methods used were: (a) self-administered questionnaire 3 months postpartum, (b) self-administered questionnaire 18 months postpartum, (c) registrations from health visitors visiting the families several times within...... weeks, and the mean age when introduced to complementary foods from 19 to 21 weeks. The mean duration of any breastfeeding was 33 weeks across methods. CONCLUSIONS: Compared with the weekly SMS questions, the self-administered questionnaires and the health visitors' reports resulted in a greater...

  10. The benefits of endurance training in cardiomyocyte function in hypertensive rats are reversed within four weeks of detraining.

    Science.gov (United States)

    Carneiro-Júnior, Miguel Araujo; Quintão-Júnior, Judson Fonseca; Drummond, Lucas Rios; Lavorato, Victor Neiva; Drummond, Filipe Rios; da Cunha, Daise Nunes Queiroz; Amadeu, Marco Aurélio; Felix, Leonardo Bonato; de Oliveira, Edilamar Menezes; Cruz, Jader Santos; Prímola-Gomes, Thales Nicolau; Mill, José Geraldo; Natali, Antonio José

    2013-04-01

    The aim of the present study was to verify the effects of low-intensity endurance training and detraining on the mechanical and molecular properties of cardiomyocytes from spontaneously hypertensive rats (SHRs). Male SHRs and normotensive control Wistar rats at 16-weeks of age were randomly divided into eight groups of eight animals: NC8 and HC8 (normotensive and hypertensive control for 8weeks); NT8 and HT8 (normotensive and hypertensive trained at 50-60% of maximal exercise capacity for 8weeks); NC12 and HC12 (normotensive and hypertensive control for 12weeks); NDT and HDT (normotensive and hypertensive trained for 8weeks and detrained for 4weeks). The total exercise time until fatigue (TTF) was determined by a maximal exercise capacity test. Resting heart rate (RHR) and systolic arterial pressure (SAP) were measured. After the treatments, animals were killed by cervical dislocation and left ventricular myocytes were isolated by enzymatic dispersion. Isolated cells were used to determine intracellular global Ca(2+) ([Ca(2+)]i) transient and cardiomyocyte contractility (1Hz; ~25°C). [Ca(2+)]i regulatory proteins were measured by Western blot, and the markers of pathologic cardiac hypertrophy by quantitative real-time polymerase chain reaction (q-RT-PCR). Exercise training augmented the TTF (NC8, 11.4±1.5min vs. NT8, 22.5±1.4min; HC8, 11.7±1.4min vs. HT8, 24.5±1.3min; Pendurance training induces positive benefits to left ventricular myocyte mechanical and molecular properties, which are reversed within 4weeks of detraining. Copyright © 2013 Elsevier Ltd. All rights reserved.

  11. Behaviour of fast- and slow growing broilers to 12 weeks of age and the physical consequences

    NARCIS (Netherlands)

    Bokkers, E.A.M.; Koene, P.

    2003-01-01

    Behaviour of broilers up to 6 weeks of age has been studied extensively, but little is known what happens after 6 weeks. Insight in the behavioural abilities after 6 weeks may also yield insight in the period before 6 weeks as the disbalance between motivation and physical abilities is more clearly

  12. Six Weeks Habituation of Simulated Barefoot Running Induces Neuromuscular Adaptations and Changes in Foot Strike Patterns in Female Runners

    Science.gov (United States)

    Khowailed, Iman Akef; Petrofsky, Jerrold; Lohman, Everett; Daher, Noha

    2015-01-01

    Background The aim of this study was to examine the effects of a 6-week training program of simulated barefoot running (SBR) on running kinetics in habitually shod (wearing shoes) female recreational runners. Material/Methods Twelve female runners age 25.7±3.4 years gradually increased running distance in Vibram FiveFingers minimal shoes over a 6-week period. The kinetic analysis of treadmill running at 10 Km/h was performed pre- and post-intervention in shod running, non-habituated SBR, and habituated SBR conditions. Spatiotemporal parameters, ground reaction force components, and electromyography (EMG) were measured in all conditions. Results Post-intervention data indicated a significant decrease across time in the habituation SBR for EMG activity of the tibialis anterior (TA) in the pre-activation and absorptive phase of running (Prunning, unhabituated SBR, and habituated SBR. Six weeks of SBR was associated with a significant decrease in the loading rates and impact forces. Additionally, SBR significantly decrease the stride length, step duration, and flight time, and stride frequency was significantly higher compared to shod running. Conclusions The findings of this study indicate that changes in motor patterns in previously habitually shod runners are possible and can be accomplished within 6 weeks. Non-habituation SBR did not show a significant neuromuscular adaptation in the EMG activity of TA and GAS as manifested after 6 weeks of habituated SBR. PMID:26166443

  13. Effects of a 12-Week Modified German Volume Training Program on Muscle Strength and Hypertrophy—A Pilot Study

    Directory of Open Access Journals (Sweden)

    Daniel A. Hackett

    2018-01-01

    Full Text Available This study investigated the effect of a 12-week modified German Volume Training intervention, or the 10 sets method, on muscle strength and hypertrophy. Twelve healthy males were randomly assigned to either a 5-SET or 10-SET group and performed 5 or 10 sets, respectively, of 10 repetitions at 60–80% one-repetition maximum (1RM. Muscle strength and body composition measures were taken at baseline, six weeks, and after 12 weeks of training. No significant changes in total, trunk, and arm lean mass were found within and between groups at any time point. There was no significant difference between groups for lean leg mass. However, a decrease in lean leg mass was observed within the 10-SET group between six and 12 weeks (p = 0.02. An increase in 1RM bench press was found within the 5-SET group at week 6 (p = 0.001 and 12 (p = 0.001 when compared to baseline, while no increases in 1RM leg press were observed at any time point within any group. No significant differences were found for 1RM bench press and leg press between groups. For 1RM bench press moderate effect sizes (ES favored 5-SET and for 1RM leg press small ESs favored 10-SET. Findings suggest performing >5 sets per exercise does not promote greater gains in muscle strength and hypertrophy. Future research should aim to substantiate these preliminary findings in a larger cohort.

  14. Heart rate and flow velocity variability as determined from umbilical Doppler velocimetry at 10-20 weeks of gestation.

    Science.gov (United States)

    Ursem, N T; Struijk, P C; Hop, W C; Clark, E B; Keller, B B; Wladimiroff, J W

    1998-11-01

    1. The aim of this study was to define from umbilical artery flow velocity waveforms absolute peak systolic and time-averaged velocity, fetal heart rate, fetal heart rate variability and flow velocity variability, and the relation between fetal heart rate and velocity variables in early pregnancy.2.A total of 108 women presenting with a normal pregnancy from 10 to 20 weeks of gestation consented to participate in a cross-sectional study design. Doppler ultrasound recordings were made from the free-floating loop of the umbilical cord.3. Umbilical artery peak systolic and time-averaged velocity increased at 10-20 weeks, whereas fetal heart rate decreased at 10-15 weeks of gestation and plateaued thereafter. Umbilical artery peak systolic velocity variability and fetal heart rate variability increased at 10-20 and 15-20 weeks respectively.4. The inverse relationship between umbilical artery flow velocity and fetal heart rate at 10-15 weeks of gestation suggests that the Frank-Starling mechanism regulates cardiovascular control as early as the late first and early second trimesters of pregnancy. A different underlying mechanism is suggested for the observed variability profiles in heart rate and umbilical artery peak systolic velocity. It is speculated that heart rate variability is mediated by maturation of the parasympathetic nervous system, whereas peak systolic velocity variability reflects the activation of a haemodynamic feedback mechanism.

  15. Study of four week repeated dose toxic test of Sweet Bee Venom in Beagle Dogs

    Directory of Open Access Journals (Sweden)

    Jae-Seuk Park

    2010-12-01

    Full Text Available Objectives: This study was performed to analyse four week repeated dose toxicity of Sweet Bee Venom(Sweet BV extracted from the bee venom in Beagle dogs. Methods: All experiments were conducted under the regulations of Good Laboratory Practice (GLP at Biotoxtech Company, a non-clinical study authorized institution. Male and female Beagle dogs of 5-6 months old were chosen for the pilot study of four week repeated dose toxicity of Sweet BV which was administered at the level of 0.56㎎/㎏ body weight which is eighty times higher than the clinical application dosage as the high dosage, followed by 0.28 and 0.14㎎/㎏ as midium and low dosage, respectively. Equal amount of excipient(normal saline to the Sweet BV experiment groups was administered as the control group every day for four weeks. Results: 1. No mortality was witnessed in all of the experiment groups. 2. All experiment groups were appealed pain sense in the treating time compared to the control group, and hyperemia and movement disorder were observed around the area of administration in all experiment groups, and higher occurrence in the higher dosage treatment. 3. For weight measurement, Neither male nor female groups showed significant changes. 4. In the urine analysis, CBC and biochemistry didn't show any significant changes in the experiment groups compared with control group. 5. For weight measurement of organs, experiment groups didn't show any significant changes compared with control group. 6. To verify abnormalities of organs and tissues, thigh muscle which treated with Sweet BV, cerebrum, liver, lung, kidney, and spinal cords were removed and conducted histologocal observation with H-E staining. In the histologocal observation of thigh muscle, cell infiltration, inflammatory, degeneration, necrosis of muscle fiber, and fibrosis were found in both thigh tissue. And the changes were depend on the dose of Sweet BV. But another organs were not detected in any abnormalities. 7

  16. Coordination and Convening of the 2016 Arctic Science Summit Week

    Energy Technology Data Exchange (ETDEWEB)

    Hinzman, Larry D. [Univ. of Alaska, Fairbanks, AK (United States)

    2016-11-13

    The Arctic Science Summit Week, Arctic Observing Summit, Arctic Council Senior Arctic Officials, Model Arctic Council, and International Arctic Assembly were convened on the campus of the University of Alaska Fairbanks with great productivity and satisfaction of the participants. We were pleased to welcome over 1000 participants from 30 different nations and over 130 different institutions. The organization and execution of these meetings was extensive and complex involving more than 250 coordinators, volunteers and contributors from across Alaska. The participants were enthusiastic in their praise of the content and accomplishments of the meeting, but they were equally happy about the genuine welcome offered to our guests by the people of Alaska. Hosting a complex event such as this summit required an army of supporting services and we were blessed to have volunteers from Fairbanks, North Pole, Anchorage and other communities throughout Alaska helping us meet these needs. This truly was an event hosted by the people of Alaska. The significance of these events cannot be overstated. The US and global communities are finally coming to the realization of the important role that the Arctic plays in international politics, economics, and science. The Arctic has experienced tremendous changes in recent years, offering new opportunities that may be addressed through international collaborations, and serious challenges that must be addressed through active investment, adaptation and national and international coordination. Over 10% of the meeting participants were indigenous peoples, from indigenous organizations or hailed from small remote communities. This is still lower than we had hoped, but it is greater participation than similar meetings have experienced in the past. It is through such engagement that we can attack problems related to the changing environment, stagnant economies, and social ills.

  17. Forgiveness, Stress, and Health: a 5-Week Dynamic Parallel Process Study.

    Science.gov (United States)

    Toussaint, Loren L; Shields, Grant S; Slavich, George M

    2016-10-01

    Psychological stress is a well-known risk factor for poor health, and recent research has suggested that the emotion-focused coping process of forgiveness may help mitigate these effects. To date, however, no studies have examined how levels of forgiveness, stress, and health fluctuate and interrelate over time. We addressed this issue by examining how forgiveness, stress, and mental and physical health symptoms change and relate to one another over 5 weeks. We hypothesized that increases in state levels of forgiveness would be associated with decreases in perceptions of stress, which would in turn be related to decreases in mental and physical health symptoms. A reverse effects model was also tested. We recruited a large, community-based sample of 332 young, middle-aged, and older adults (16-79 years old; M age  = 27.9). Each week for 5 weeks, participants reported on their levels of state forgiveness, perceived stress, and mental and physical health symptoms. Levels of forgiveness, stress, and mental and physical health symptoms each showed significant change and individual variability in change over time. As hypothesized, increases in forgiveness were associated with decreases in stress, which were in turn related to decreases in mental (but not physical) health symptoms (i.e., forgiveness → stress → health). The reverse effects model (i.e., health → stress → forgiveness) provided a relatively poorer fit. This study is the first to provide prospective, longitudinal evidence showing that greater forgiveness is associated with less stress and, in turn, better mental health. Strategies for cultivating forgiveness may thus have beneficial effects on stress and health.

  18. The Effect of Computer-Based Self-Access Learning on Weekly Vocabulary Test Scores

    Directory of Open Access Journals (Sweden)

    Jordan Dreyer

    2014-09-01

    Full Text Available This study sets out to clarify the effectiveness of using an online vocabulary study tool, Quizlet, in an urban high school language arts class. Previous similar studies have mostly dealt with English Language Learners in college settings (Chui, 2013, and were therefore not directed at the issue self-efficacy that is at the heart of the problem of urban high school students in America entering remedial writing programs (Rose, 1989. The study involves 95 students over the course of 14 weeks. Students were tested weekly and were asked to use the Quizlet program in their own free time. The result of this optional involvement was that many students did not participate in the treatment and therefore acted as an elective control group. The resultant data collected shows a strong correlation between the use of an online vocabulary review program and short-term vocabulary retention. The study also showed that students who paced themselves and spread out their study sessions outperformed those students who used the program only for last minute “cram sessions.” The implications of the study are that students who take advantage of tools outside of the classroom are able to out perform their peers. The results are also in line with the call to include technology in the Basic Writing classroom not simply as a tool, but as a “form of discourse” (Jonaitis, 2012. Weekly vocabulary tests, combined with the daily online activity as reported by Quizlet, show that: 1 utilizing the review software improved the scores of most students, 2 those students who used Quizlet to review more than a single time (i.e., several days before the test outperformed those who only used the product once, and 3 students who professed proficiency with the “notebook” system of vocabulary learning appeared not to need the treatment.

  19. [Embryo volume estimated by three-dimensional ultrasonography at seven to ten weeks of pregnancy].

    Science.gov (United States)

    Filho, João Bortoletti; Nardozza, Luciano Marcondes Machado; Araujo Júnior, Edward; Rôlo, Líliam Cristine; Nowak, Paulo Martin; Moron, Antonio Fernandes

    2008-10-01

    to evaluate the embryo's volume (EV) between the seventh and the tenth gestational week, through tridimensional ultrasonography. a transversal study with 63 normal pregnant women between the seventh and the tenth gestational week. The ultrasonographical exams have been performed with a volumetric abdominal transducer. Virtual Organ Computer-aided Analysis (VOCAL) has been used to calculate EV, with a rotation angle of 12 masculine and a delimitation of 15 sequential slides. The average, median, standard deviation and maximum and minimum values have been calculated for the EV in all the gestational ages. A dispersion graphic has been drawn to assess the correlation between EV and the craniogluteal length (CGL), the adjustment being done by the determination coefficient (R(2)). To determine EV's reference intervals as a function of the CGL, the following formula was used: percentile=EV+K versus SD, with K=1.96. CGL has varied from 9.0 to 39.7 mm, with an average of 23.9 mm (+/-7.9 mm), while EV has varied from 0.1 to 7.6 cm(3), with an average of 2.7 cm(3) (+/-3.2 cm(3)). EV was highly correlated to CGL, the best adjustment being obtained with quadratic regression (EV=0.2-0.055 versus CGL+0.005 versus CGL(2); R(2)=0.8). The average EV has varied from 0.1 (-0.3 to 0.5 cm(3)) to 6.7 cm(3) (3.8 to 9.7 cm(3)) within the interval of 9 to 40 mm of CGL. EV has increased 67 times in this interval, while CGL, only 4.4 times. EV is a more sensitive parameter than CGL to evaluate embryo growth between the seventh and the tenth week of gestation.

  20. Automatic Trip Detection with the Dutch Mobile Mobility Panel: Towards Reliable Multiple-Week Trip Registration for Large Samples

    NARCIS (Netherlands)

    Thomas, Tom; Geurs, Karst T.; Koolwaaij, Johan; Bijlsma, Marcel E.

    2018-01-01

    This paper examines the accuracy of trip and mode choice detection of the last wave of the Dutch Mobile Mobility Panel, a large-scale three-year, smartphone-based travel survey. Departure and arrival times, origins, destinations, modes, and travel purposes were recorded during a four week period in

  1. Cisplatin improves antitumor activity of weekly nab-paclitaxel in patients with metastatic breast cancer

    Directory of Open Access Journals (Sweden)

    Sun S

    2014-03-01

    Full Text Available Si Sun,1 Lichen Tang,2 Jian Zhang,1 Fangfang Lv,1 Zhonghua Wang,1 Leiping Wang,1 Qunling Zhang,1 Chunlei Zheng,1 Lixin Qiu,1 Zhen Jia,1 Yunhua Lu,1 Guangyu Liu,2 Zhimin Shao,2 Biyun Wang,1 Xichun Hu1 1Department of Medical Oncology, Fudan University Shanghai Cancer Center, Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, People's Republic of China, 2Department of Breast Surgery, Fudan University Shanghai Cancer Center, Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, People's Republic of China Abstract: Although nanoparticle albumin-bound paclitaxel (nab-paclitaxel is approved to be given every 3 weeks, weekly use of this drug is becoming a new standard of care in patients with metastatic breast cancer (MBC. This prospective Phase II study was conducted to improve the efficacy of weekly nab-paclitaxel with cisplatin in MBC patients. Seventy-three women with recurrent or MBC were eligible for participation. Nab-paclitaxel was administered weekly at a dose of 125 mg/m2 on day 1, day 8, and day 15, followed by cisplatin 75 mg/m2 on day 1, repeated every 28 days with a maximum of 6 cycles. The primary objective was investigator-assessed overall response rate (ORR. A high ORR of 67.1% was obtained, with rates of 80.6% for the first-line patients and 80% for patients not pretreated with taxanes. Among those who had objective responses, a large percentage of patients (83.7% showed quickly remarkable tumor shrinkage during the first two cycles. The median progression-free and overall survival times were 9.8 and 26.9 months, respectively. For the patients receiving first-, second-, and third-line therapy or beyond, median progression-free survival was 11.7, 7.7, and 7.6 months, respectively (P=0.005. Molecular subtype was not significantly associated with ORR or disease progression. Grade 4 neutropenia occurred in 46 patients (63.0%, with febrile neutropenia found in 9 patients (12.3%. Grade 3

  2. Clinical Application of Revised Laboratory Classification Criteria for Antiphospholipid Antibody Syndrome: Is the Follow-Up Interval of 12 Weeks Instead of 6 Weeks Significantly Useful?

    Directory of Open Access Journals (Sweden)

    Sang Hyuk Park

    2016-01-01

    Full Text Available Background. According to revised classification criteria of true antiphospholipid antibody syndrome, at least one of three antiphospholipid antibodies should be present on two or more occasions at least 12 weeks apart. However, it can be inconvenient to perform follow-up tests with interval of 12 weeks. We investigated clinical application of follow-up tests with interval of 12 weeks. Method. Totals of 67, 199, and 332 patients tested positive initially for the lupus anticoagulants confirm, the anti-β2 glycoprotein-I antibody, and the anti-cardiolipin antibody test, respectively, from Jan 2007 to Jul 2009. We investigated clinical symptoms of patients, follow-up interval, and results of each test. Results. Among patients with initial test positive, 1.5%–8.5% were subjected to follow-up tests at interval of more than 12 weeks. Among 25 patients with negative conversion in tests, patients with interval of more than 12 weeks showed clinical symptom positivity of 33.3%, which was higher than that of 12.5% with 6–12 weeks. Among 34 patients with persistent test positive, clinical symptoms positivity trended to be more evident in patients at interval of 6–12 weeks (47.4% versus 26.7%, P=0.191 than more than 12 weeks. Conclusion. Less than 10% of patients with initial test positive had follow-up tests at interval of more than 12 weeks and the patients with persistent test positive at interval of more than 12 weeks showed trends toward having lower clinical symptoms than 6–12 weeks. More research is needed focused on the evidence that follow-up test at interval of more than 12 weeks should be performed instead of 6 weeks.

  3. Separating the mink dam from the litter at 7 or 8 weeks after delivery

    DEFF Research Database (Denmark)

    Malmkvist, Jens; Palme, Rupert; Larsen, Torben

    2015-01-01

    The optimal timing of separating the mink dam from the litter is suggested to be a balance between the partly conflicting needs of the mother and the kits. Early removal of the dam or partial removal of the litter may protect the dam against exhaustion. Little is known about the maternal motivation...... around the time of separation. Therefore, we investigated the effects of separating the dam from the litter, using brown first-parity dams (N=374) randomly assigned within each date of delivery to two treatment groups: The dam was taken away from the litter either at day 49 ±1 (7w, N=185) or at day 56 ±1...... (8w, N=189) after birth. The aim was to investigate whether the dams had a different motivation to take care of the litter after 7 and 8 weeks, estimated by non-invasive determination of cortisol (FCM: Faecal Corticsol Metabolites) and dam calls the first week after separation. The two treatment...

  4. Effects of 12-week overground walking training at ventilatory threshold velocity in type 2 diabetic women.

    Science.gov (United States)

    Belli, Taisa; Ribeiro, Luiz Fernando Paulino; Ackermann, Marco Aurélio; Baldissera, Vilmar; Gobatto, Claudio Alexandre; Galdino da Silva, Rozinaldo

    2011-09-01

    This study analyzed the effects of overground walking training at ventilatory threshold (VT) velocity on glycaemic control, body composition, physical fitness and lipid profile in DM2 women. Nineteen sedentary patients were randomly assigned to a control group (CG; n=10, 55.9±2.2 years) or a trained group (TG; n=9, 53.4±2.3 years). Both groups were subjected to anthropometric measures, a 12-h fasting blood sampling and a graded treadmill exercise test at baseline and after a 12-week period, during which TG followed a training program involving overground walking at VT velocity for 20-60min/session three times/week. Significant group×time interactions (P0.05) in fasting blood glucose, submaximal fitness parameters and lipid profile. Our results suggest that overground walking training at VT velocity improves long term glycaemic control, body composition and exercise capacity, attesting for the relevance of this parameter as an effective strategy for the exercise intensity prescription in DM2 population. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

  5. 78 FR 24319 - National Crime Victims' Rights Week, 2013

    Science.gov (United States)

    2013-04-24

    ... we know: families trying to rebuild after financial fraud or identity theft, grandparents spending... victims of abuse. We have continued to crack down on financial crimes that leave too many families..., and by volunteering to serve victims in their time of need. [[Page 24320

  6. 75 FR 71523 - National Farm-City Week, 2010

    Science.gov (United States)

    2010-11-24

    ... continue supporting the vital relationship between American farms and families, and work to ensure that farming remains an economically, socially, and environmentally sustainable way of life for future... friends during this time of Thanksgiving, let us celebrate farms of every size that produce the abundance...

  7. Postpartum major depression at six weeks in primary health care ...

    African Journals Online (AJOL)

    Background: Major depression is a common and disabling complication of the postpartum period in women. It is thought to occur three times more commonly in the developing than in developed countries. Objectives: The objectives of this study were to determine the prevalence of and factors associated with major ...

  8. Neuromuscular adaptations to 4 weeks of intensive drop jump training in well-trained athletes

    DEFF Research Database (Denmark)

    Alkjær, Tine; Meyland, Jacob; Raffalt, Peter C

    2013-01-01

    This study examined the effects of 4 weeks of intensive drop jump training in well-trained athletes on jumping performance and underlying changes in biomechanics and neuromuscular adaptations. Nine well-trained athletes at high national competition level within sprinting and jumping disciplines...... participated in the study. The training was supervised and augmented feedback on performance was used to ensure maximal training intensity. The drop jumps were performed with minimal contact time and maximal jumping height. Assessment of performance during training showed effects of motor learning. Before...... and after the training intervention maximal isometric muscle strength, the biomechanics, muscle activity pattern of the lower extremities and the soleus H-reflex and V-wave during drop jumping were measured. Maximal jump height and performance index (PI) defined as jumping height divided by contact time...

  9. Intensive foreign language learning reveals effects on categorical perception of sibilant voicing after only 3 weeks

    DEFF Research Database (Denmark)

    Nielsen, Andreas Højlund; Horn, Nynne Thorup; Derdau Sørensen, Stine

    2015-01-01

    Models of speech learning suggest that adaptations to foreign language sound categories take place within 6-12 months of exposure to a foreign language. Results from laboratory language training show effects of very targeted training on non-native speech contrasts within only one to three weeks...... of training. Results from immersion studies are inconclusive, but some suggest continued effects on non-native speech perception after 6-8 years of experience. We investigated this apparent discrepancy in the timing of adaptation to foreign speech sounds in a longitudinal study of foreign language learning....... We examined two groups of Danish language officer cadets learning either Arabic (MSA and Egyptian Arabic) or Dari (Afghan Farsi) through intensive multi-faceted language training. We conducted two experiments (identification and discrimination) with the cadets who were tested four times: at the start...

  10. Tamsulosin does not increase 1-week passage rate of ureteral stones in ED patients.

    Science.gov (United States)

    Berger, David A; Ross, Michael A; Hollander, Jay B; Ziadeh, James; Chen, Charity; Jackson, Raymond E; Swor, Robert A

    2015-12-01

    The objective of the study is to determine if tamsulosin initiated in the emergency department (ED) decreases the time to ureteral stone passage at 1 week or time to pain resolution, compared to placebo. We performed a prospective, randomized, double-blinded, placebo-controlled trial of tamsulosin vs placebo in ED patients with ureterolithiasis on computed tomography. Patients were identified and enrolled between April 2007 and February 2009 and were randomized to either 0.4 mg of tamsulosin or placebo for 1 week. We contacted participants using a telephone survey on post-ED visit days 1, 2, 3, and 7. The primary outcome was time to stone passage, with secondary outcomes being maximum pain score and amount of pain medication required. Of the 127 patients enrolled during this study, 15 were lost to follow-up, and 12 required surgical interventions before the 7-day mark, leaving 100 patients for analysis. Of the 100 patients, 53 received tamsulosin and 47 received placebo. There was no difference between groups in percentage of male, mean age, initial serum creatinine, average stone size, stone location, and history of prior stone. The probability that the patient did not pass a stone at 7 days was not different between tamsulosin and placebo, 62.1% (95% confidence interval, 49.1%-75.1%) vs 54.4% (95% confidence interval, 40.3%-68.6%; P = .58). There was no significant difference in the high pain score (P = .12) or hydrocodone/acetaminophen intake (P = .76) between treatment groups at any of the time points. This study reveals no difference in the proportion of stone passage or high pain score and pain medication utilization at 7 days between tamsulosin and placebo. Copyright © 2015 Elsevier Inc. All rights reserved.

  11. Analisis Fenomena Day of the Week Effect: Pengujian Monday Effect, Week-Four Effect and Rogalski Effect (Studi Empiris Pada Perusahaan LQ 45 Di BEI)

    OpenAIRE

    Satoto, Shinta Heru

    2011-01-01

    The purpose of this study were to provide an empirical evidence of the day of the week phenomenon in Indonesian Capital Market. This research used 39 sample firms that list on LQ 45 Indonesian Capital Market on January 1, 2009 until December 31, 2010. The results indicate that Monday returns are positive and significant on average, and significantly different from returns of the rest of the week. Thus, no evidence was uncovered to support Monday effect and week four effect in Indonesian capit...

  12. Children's physical activity during a segmented school week

    DEFF Research Database (Denmark)

    Schneller, Mikkel Bo; Schipperijn, Jasper; Nielsen, Glen

    2017-01-01

    BACKGROUND: Movement integration (MI) into traditional classroom teaching is a promising opportunity for children to increase physical activity (PA). Education outside the classroom (EOtC) can be regarded as MI, and has increased children's PA in case studies. The aim of this study is to investig......BACKGROUND: Movement integration (MI) into traditional classroom teaching is a promising opportunity for children to increase physical activity (PA). Education outside the classroom (EOtC) can be regarded as MI, and has increased children's PA in case studies. The aim of this study...... (10.89 ± 1.03 years) participants with 7 days of 24 h wear time per day were included in a day type PA analysis, and 194 of these participants (10.46 ± 0.99 years) provided information on time spent in specific domains (e.g. EOtC or recess) and were included in a domain-specific PA analysis....... Differences in proportion of time spent in PA intensities were tested using mixed-effects regression models. RESULTS: More moderate-to-vigorous physical activity (MVPA) occurred on days with physical education (PE) than days with EOtC (girls 0.79%, p = .001, CI = .26% to 1.31%; boys 1.35%, p = .003, CI = .32...

  13. Daily sleep, weekly working hours, and risk of work-related injury: US National Health Interview Survey (2004-2008).

    Science.gov (United States)

    Lombardi, David A; Folkard, Simon; Willetts, Joanna L; Smith, Gordon S

    2010-07-01

    The impact on health and safety of the combination of chronic sleep deficits and extended working hours has received worldwide attention. Using the National Health Interview Survey (NHIS), an in-person household survey using a multistage, stratified, clustered sample design representing the US civilian, non-institutionalized population, the authors estimated the effect of total daily self-reported sleep time and weekly working hours on the risk of a work-related injury. During the survey period 2004-2008, 177,576 persons (ages 18-74) sampled within households reported that they worked at a paid job the previous week and reported their total weekly work hours. A randomly selected adult in each household (n = 75,718) was asked to report his/her usual (average) total daily sleep hours the prior week; complete responses were obtained for 74,415 (98.3%) workers. Weighted annualized work-related injury rates were then estimated across a priori defined categories of both average total daily sleep hours and weekly working hours. To account for the complex sampling design, weighted multiple logistic regression was used to independently estimate the risk of a work-related injury for categories of usual daily sleep duration and weekly working hours, controlling for important covariates and potential confounders of age, sex, race/ethnicity, education, type of pay, industry, occupation (proxy for job risk), body mass index, and the interaction between sleep duration and work hours. Based on the inclusion criteria, there were an estimated 129,950,376 workers annually at risk and 3,634,446 work-related medically treated injury episodes (overall injury rate 2.80/100 workers). Unadjusted annualized injury rates/100 workers across weekly work hours were 2.03 (60 h). With regards to self-reported daily sleep time, the estimated annualized injury rates/100 workers were 7.89 (10 h). After controlling for weekly work hours, and aforementioned covariates, significant increases in risk/1

  14. Effectiveness and Cost-Effectiveness of Different Weekly Frequencies of Pilates for Chronic Low Back Pain: Randomized Controlled Trial.

    Science.gov (United States)

    Miyamoto, Gisela Cristiane; Moura, Katherinne Ferro; Franco, Yuri Rafael dos Santos; Oliveira, Naiane Teixeira Bastos de; Amaral, Diego Diulgeroglo Vicco; Branco, Amanda Nery Castelo; Silva, Maria Liliane da; Lin, Christine; Cabral, Cristina Maria Nunes

    2016-03-01

    The Pilates method has been recommended to patients with low back pain, but the evidence on effectiveness is inconclusive. In addition, there is still no evidence for the cost-effectiveness of this method or for the ideal number of sessions to achieve the highest effectiveness. The aim of this study will be to investigate the effectiveness and cost-effectiveness of the Pilates method with different weekly frequencies in the treatment of patients with nonspecific low back pain. This is a randomized controlled trial with blinded assessor. This study will be conducted at a physical therapy clinic in São Paulo, Brazil. Two hundred ninety-six patients with nonspecific low back pain between the ages of 18 and 80 years will be assessed and randomly allocated to 4 groups (n=74 patients per group). All groups will receive an educational booklet. The booklet group will not receive additional exercises. Pilates group 1 will follow a Pilates-based program once a week, Pilates group 2 will follow the same program twice a week, and Pilates group 3 will follow the same program 3 times a week. The intervention will last 6 weeks. A blinded assessor will evaluate pain, quality-adjusted life-years, general and specific disability, kinesiophobia, pain catastrophizing, and global perceived effect 6 weeks, 6 months, and 12 months after randomization. Therapists and patients will not be blinded. This will be the first study to investigate different weekly frequencies of treatment sessions for nonspecific low back pain. The results of this study will contribute to a better definition of treatment programs for this population. © 2016 American Physical Therapy Association.

  15. Weekly brief phone support in self-help cognitive behavioral therapy for insomnia disorder: Relevance to adherence and efficacy.

    Science.gov (United States)

    Ho, Fiona Yan-Yee; Chung, Ka-Fai; Yeung, Wing-Fai; Ng, Tommy Ho-Yee; Cheng, Sammy Kin-Wing

    2014-12-01

    Self-help cognitive-behavioral therapy for insomnia (CBT-I) is an acceptable, low-intensity treatment in a stepped care model for insomnia. We tested the application of self-help CBT-I in a Chinese population. 312 participants with self-report of insomnia associated with distress or daytime impairment 3 or more nights per week for at least 3 months were randomized to self-help CBT-I with telephone support (SHS), self-help CBT-I (SH) and waiting-list (WL). The program was Internet-based with treatment materials delivered once per week, and lasted for 6 consecutive weeks, while the telephone support was limited to 15 min weekly. Mixed-effects analyses found significant group by time interaction in sleep and sleep-related cognitions at immediate and 4-week posttreatment. Post-hoc pairwise comparison with WL revealed that both SHS and SH had significantly higher sleep efficiency at immediate (p = .004 and p = .03, respectively) and 4-week posttreatment (p = .002 and p = .02, respectively) and lower insomnia and dysfunctional beliefs scores. The SHS group had additional improvements in sleep onset latency and sleep quality. Benefits with self-help CBT-I were maintained at 12-week posttreatment, but attrition rate was about 35%. Internet-based self-help CBT-I was effective and acceptable for treating insomnia in the Chinese population. A brief telephone support further enhanced the efficacy. Copyright © 2014 Elsevier Ltd. All rights reserved.

  16. Six weeks of unsupervised Nintendo Wii Fit gaming is effective at improving balance in independent older adults.

    Science.gov (United States)

    Nicholson, Vaughan Patrick; McKean, Mark; Lowe, John; Fawcett, Christine; Burkett, Brendan

    2015-01-01

    To determine the effectiveness of unsupervised Nintendo Wii Fit balance training in older adults. Forty-one older adults were recruited from local retirement villages and educational settings to participate in a six-week two-group repeated measures study. The Wii group (n = 19, 75 ± 6 years) undertook 30 min of unsupervised Wii balance gaming three times per week in their retirement village while the comparison group (n = 22, 74 ± 5 years) continued with their usual exercise program. Participants' balance abilities were assessed pre- and postintervention. The Wii Fit group demonstrated significant improvements (P balance, lateral reach (left and right), and gait speed compared with the comparison group. Reported levels of enjoyment following game play increased during the study. Six weeks of unsupervised Wii balance training is an effective modality for improving balance in independent older adults.

  17. Can a 5 Week Strength Training Program Produce Range of Motion Adaptations in Amateur Female Tennis Players?

    Directory of Open Access Journals (Sweden)

    Andrew L. SHIM

    2015-12-01

    Full Text Available Objective: The purpose of this study was to assess range of motion adaptations in amateur tennis players based on the effects of a five week strength training program on the dominant and non-dominant arm. Subjects: An experimental and control group of six collegiate women tennis players (Div II and NAIA participated. After initial assessment, six subjects participated in a five week, four times a week, pre-season strength training program consisting of five exercises: External Rotation 90°, Seated Row, Scaption, Chest Press, and External Shoulder Rotation (Rubber tubing. Results: Data analysis through a paired t-test showed that there were no significant changes in ROM in the experimental group when compared to the control group. In conclusion, a strength training program is highly recommended for female overhead athletes combined with a proper flexibility regimen to promote best practice.

  18. [Effects of HiLo for two weeks on erythrocyte immune adhesion and leukocyte count of swimmers].

    Science.gov (United States)

    Zhao, Yong-Cai; Gao, Bing-Hong; Wu, Ge-Lin; Zhang, Jiu-Li

    2012-07-01

    To investigate the effects of living high-training low (HiLo) on innate immunity in blood of elite swimmers. Six female swimmers undertook HiLo for two weeks, erythrocyte adhesion function and counts of leukocyte were tested in different time of training period. Red blood cell C3b receptor ring rate (RBC-C3bRR) decreased and red blood cell immune complex matter ring rate (RBC-ICR) increased significantly (P < 0.05), the two markers returned to base line 1 week after training. Counts of leukocyte and granulocyte decreased significantly (P < 0.05), and they recovered 1 week after training; Counts of lymphocyte and monocyte decreased without significance during training and did not recovered after training. Immunity of erythrocyte and granulocyte decreased quickly, but lymphocyte and monocyte recovered slowly, swimmers were adaptive to the training.

  19. Predictors of lapse in first week of smoking abstinence in PTSD and non-PTSD smokers.

    Science.gov (United States)

    Beckham, Jean C; Calhoun, Patrick S; Dennis, Michelle F; Wilson, Sarah M; Dedert, Eric A

    2013-06-01

    Retrospective research suggests smokers with posttraumatic stress disorder (PTSD) lapse more quickly after their quit date. Ecological momentary assessment (EMA) research is needed to confirm the presence of early smoking lapse in PTSD and form conceptualizations that inform intervention. Smokers with (n = 55) and without (n = 52) PTSD completed alarm-prompted EMA of situational and psychiatric variables the week before and after a quit date, and self-initiated EMA following smoking lapses. Blood samples at baseline and on the quit date allowed assessment of dehydroepiandrosterone (DHEA) and dehydroepiandrosterone sulfate (DHEA(S)). PTSD was related to shorter time to lapse (hazard ratio [HR] = 1.677, 95% CI: 1.106-2.544). Increased smoking abstinence self-efficacy was related to longer time to lapse (HR = 0.608, 95% CI: 0.430-0.860). Analyses of participants' real-time reports revealed that smokers with PTSD were more likely to attribute first-time lapses to negative affect ( = 5.412, p = .020), and trauma reminders (Fisher's exact p = .003**). Finally, the quit date decrease in DHEA(S) was related to shorter time to lapse (HR = 1.009, 95% CI: 1.000-1.018, p smoking lapse in PTSD, and add to evidence that early lapse occasions are more strongly related to trauma reminders, negative affect, and cravings in smokers with PTSD.

  20. Do 12-Week Yoga Program Influence Respiratory Function Of Elderly Women?

    Directory of Open Access Journals (Sweden)

    Bezerra Lídia Aguiar

    2014-12-01

    Full Text Available Aging produces several respiratory limitations and reduces tolerance to physical efforts, sometimes leading to pulmonary diseases in the elderly. The literature draws attention to the possible benefits of Yoga practice among the elderly, presenting evidence for significant improvements in quality of life. It was hypothesized that yoga practice can improve respiratory function in the elderly. The effects of a yoga program on pulmonary volumes and respiratory muscle strength were verified in 36 elderly women divided into a yoga group [YG] (63.1 ± 13.3 years of age and a control group (61.0 ± 6.9 years of age. Maximal inspiratory and expiratory pressure (MIP and MEP were assessed by a manovacuometer and tidal volume (VT, vital capacity (VC and minute ventilation (VE were measured by a ventilometer. The program comprised 65 min sessions, 3 times/week during 12 weeks. The heart rate and respiratory rate decreased significantly in the YG (76-39 ± 8-03 vs. 74-61±10.26 bpm and 18.61 ± 3.15 vs. 16.72 ± 3.12 resp/min, respectively. In the YG, VT and VE increased significantly (0.55 ± 0.22 vs. 0.64 ± 0.2 ml and 9.19 ± 2.39 vs. 10.05 ± 2.11 ml, respectively, as well as VC (1.48 ± 0.45 vs. 2.03 ± 0.72 ml. Improvements were also found in MIP and MEP in the YG (62.17 ± 14.77 vs. 73.06 ± 20.16 cmH2O and 80.56 ± 23.94 vs. 86.39 ± 20.16 cmH2O, respectively. It was concluded that a 12-week yoga program significantly improves pulmonary function of aged women.

  1. Do 12-week yoga program influence respiratory function of elderly women?

    Science.gov (United States)

    Bezerra, Lídia Aguiar; de Melo, Helton Fabrício; Garay, Ana Paula; Reis, Victor Machado; Aidar, Felipe José; Bodas, Ana Rita; Garrido, Nuno Domingos; de Oliveira, Ricardo Jacó

    2014-09-29

    Aging produces several respiratory limitations and reduces tolerance to physical efforts, sometimes leading to pulmonary diseases in the elderly. The literature draws attention to the possible benefits of Yoga practice among the elderly, presenting evidence for significant improvements in quality of life. It was hypothesized that yoga practice can improve respiratory function in the elderly. The effects of a yoga program on pulmonary volumes and respiratory muscle strength were verified in 36 elderly women divided into a yoga group [YG] (63.1 ± 13.3 years of age) and a control group (61.0 ± 6.9 years of age). Maximal inspiratory and expiratory pressure (MIP and MEP) were assessed by a manovacuometer and tidal volume (VT), vital capacity (VC) and minute ventilation (VE) were measured by a ventilometer. The program comprised 65 min sessions, 3 times/week during 12 weeks. The heart rate and respiratory rate decreased significantly in the YG (76-39 ± 8-03 vs. 74-61±10.26 bpm and 18.61 ± 3.15 vs. 16.72 ± 3.12 resp/min, respectively). In the YG, VT and VE increased significantly (0.55 ± 0.22 vs. 0.64 ± 0.2 ml and 9.19 ± 2.39 vs. 10.05 ± 2.11 ml, respectively), as well as VC (1.48 ± 0.45 vs. 2.03 ± 0.72 ml). Improvements were also found in MIP and MEP in the YG (62.17 ± 14.77 vs. 73.06 ± 20.16 cmH2O and 80.56 ± 23.94 vs. 86.39 ± 20.16 cmH2O, respectively). It was concluded that a 12-week yoga program significantly improves pulmonary function of aged women.

  2. Ototoxicity in rats exposed to ethylbenzene and to two technical xylene vapours for 13 weeks

    Energy Technology Data Exchange (ETDEWEB)

    Gagnaire, Francois; Langlais, Cristina; Grossmann, Stephane; Wild, Pascal [Institut National de Recherche et de Securite, Departement Polluants et Sante, Vandoeuvre Cedex (France)

    2007-02-15

    Male Sprague-Dawley rats were exposed to ethylbenzene (200, 400, 600 and 800 ppm) and to two mixed xylenes (250, 500, 1,000 and 2,000 ppm total compounds) by inhalation, 6 h/day, 6 days/week for 13 weeks and sacrificed for morphological investigation 8 weeks after the end of exposure. Brainstem auditory-evoked responses were used to determine auditory thresholds at different frequencies. Ethylbenzene produced moderate to severe ototoxicity in rats exposed to the four concentrations studied. Increased thresholds were observed at 2, 4, 8 and 16 kHz in rats exposed to 400, 600 and 800 ppm ethylbenzene. Moderate to severe losses of outer hair cells of the organ of Corti occurred in animals exposed to the four concentrations studied. Exposure to both mixed xylenes produced ototoxicity characterized by increased auditory thresholds and losses of outer hair cells. Ototoxicity potentiation caused by ethylbenzene was observed. Depending on the mixed xylene studied and the area of the concentration-response curves taken into account, the concentrations of ethylbenzene in mixed xylenes necessary to cause a given ototoxicity were 1.7-2.8 times less than those of pure ethylbenzene. Given the high ototoxicity of ethylbenzene, the safety margin of less or equal to two (LOAEL/TWA) might be too small to protect workers from the potential risk of ototoxicity. Moreover, the enhanced ototoxicity of ethylbenzene and para-xylene observed in mixed xylenes should encourage the production of mixed xylenes with the lowest possible concentrations of ethylbenzene and para-xylene. (orig.)

  3. Ototoxicity in rats exposed to ethylbenzene and to two technical xylene vapours for 13 weeks.

    Science.gov (United States)

    Gagnaire, François; Langlais, Cristina; Grossmann, Stéphane; Wild, Pascal

    2007-02-01

    Male Sprague-Dawley rats were exposed to ethylbenzene (200, 400, 600 and 800 ppm) and to two mixed xylenes (250, 500, 1,000 and 2,000 ppm total compounds) by inhalation, 6 h/day, 6 days/week for 13 weeks and sacrificed for morphological investigation 8 weeks after the end of exposure. Brainstem auditory-evoked responses were used to determine auditory thresholds at different frequencies. Ethylbenzene produced moderate to severe ototoxicity in rats exposed to the four concentrations studied. Increased thresholds were observed at 2, 4, 8 and 16 kHz in rats exposed to 400, 600 and 800 ppm ethylbenzene. Moderate to severe losses of outer hair cells of the organ of Corti occurred in animals exposed to the four concentrations studied. Exposure to both mixed xylenes produced ototoxicity characterized by increased auditory thresholds and losses of outer hair cells. Ototoxicity potentiation caused by ethylbenzene was observed. Depending on the mixed xylene studied and the area of the concentration-response curves taken into account, the concentrations of ethylbenzene in mixed xylenes necessary to cause a given ototoxicity were 1.7-2.8 times less than those of pure ethylbenzene. Given the high ototoxicity of ethylbenzene, the safety margin of less or equal to two (LOAEL/TWA) might be too small to protect workers from the potential risk of ototoxicity. Moreover, the enhanced ototoxicity of ethylbenzene and para-xylene observed in mixed xylenes should encourage the production of mixed xylenes with the lowest possible concentrations of ethylbenzene and para-xylene.

  4. Impact of a 12-week wellness coaching on self-care behaviors among primary care adult patients with prediabetes

    Directory of Open Access Journals (Sweden)

    Ramona S. DeJesus

    2018-06-01

    Full Text Available This single arm prospective study assessed the impact of individualized wellness coaching intervention for primary care patients with prediabetes on self-reported changes in physical activity level and food choices. Five hundred sixty adult patients 18 years and older with prediabetes, seen in primary care clinic, were invited to participate in 12 weeks wellness coaching sessions delivered by certified coaches. Responses from questionnaires at baseline, 6 and 12 weeks were analyzed. Of 168 consented patients, 99 completed at least one coaching session; majority was elderly, female, overweight or obese. At baseline, 50% had <60 min aerobic exercise/week. At 6 and 12 weeks, average aerobic exercise time significantly increased from 117 min to 166 and 199 min respectively. Effect was sustained at 24 weeks. Success in making healthy eating choices also statistically improved from baseline. Significant effects on both activity level and eating behavior persisted even after adjusting for age, sex and baseline glucose/A1c values. Secondary outcomes of self-efficacy and quality of life likewise showed significant improvement. Results suggest that integration of wellness coaching in primary care practice among individuals at high risk for diabetes is feasible and may be useful as part of diabetes prevention management strategies in target populations. Future randomized clinical trials are needed to further explore this issue. Keywords: Wellness coaching, Primary care, Prediabetes, Preventive health, Health behavior

  5. Effects of 8-week Pilates exercise program on menopausal symptoms and lumbar strength and flexibility in postmenopausal women.

    Science.gov (United States)

    Lee, Haelim; Caguicla, Joy Matthew Cuasay; Park, Sangseo; Kwak, Dong Jick; Won, Deuk-Yeon; Park, Yunjin; Kim, Jeeyoun; Kim, Myungki

    2016-06-01

    The aim of this study was to investigate the effects of an 8-week Pilates exercise program on menopausal symptoms and lumbar strength and flexibility in postmenopausal women. In total, 74 postmenopausal women were recruited and randomly allocated to a Pilates exercise group (n=45) and a control group (n=29). Menopausal symptoms were measured through a questionnaire, while lumbar strength was measured through a lumbar extension machine, and lumbar flexibility was measured through sit-and-reach and trunk lift tests performed before and after the Pilates exercise program, respectively. The Pilates exercises consisted of 7-10 min for warm-up, 35-40 min for the main program modified from Pilates Academy International, and 5-7 min for the cool-down, and were performed 3 times a week for 8 weeks. The results showed a significant decrease in menopausal symptoms except urogenital symptoms. Also, the results presented a significant increase in lumbar strength and flexibility after 8 weeks of the Pilates exercise program. We concluded that an 8-week Pilates exercise program is effective in decreasing menopausal symptoms and increasing lumbar strength and flexibility.

  6. Maintained superiority of chronotherapeutics vs. exercise in a 20-week randomized follow-up trial in major depression

    DEFF Research Database (Denmark)

    Martiny, K; Refsgaard, E; Lund, V.

    2015-01-01

    therapies, daily bright light therapy, and sleep time stabilization or to a group using daily exercise. Patients were followed 29 weeks. We report the last 20 weeks, a follow-up phase, where medication could be altered. Patients were assessed every 4 weeks. Remission rates were primary outcome. RESULTS......: Patients in the wake group had a statistically significant higher remission rate of 61.9% vs. 37.9% in the exercise group at week 29 (OR = 2.6, CL = 1.3-5.6, P = 0.01). This indicated continued improvement compared with the 9 weeks of treatment response (44.8% vs. 23.4%) with maintenance of the large...... difference between groups. HAM-D17 endpoint scores were statistically lower in the wake group with endpoint scores of 7.5 (SE = 0.9) vs. 10.1 (SE = 0.9) in the exercise group (difference 2.7, CL = 0.5-4.8, P = 0.02). CONCLUSION: In this clinical study patients continued to improve in the follow-up phase...

  7. Comparison of peritoneal transport characteristics at the second week and at six months of peritoneal dialysis commencement

    Directory of Open Access Journals (Sweden)

    R Balasubramaniyam

    2013-01-01

    Full Text Available Peritoneal equilibration test (PET is an important tool for managing peritoneal dialysis (PD prescription. The Kidney Disease Outcomes Quality Initiative (KDOQI guidelines suggest that the first PET be performed 4-8 weeks after PD commencement. The main reason for this delay is because of the peritoneal membrane might change its character once it is exposed to the glucose based dialysate. In this study, we compared PET 2 weeks after PD commencement to PET after 6 months to evaluate the changes in the peritoneal membrane character with time. This study included 126 patients who underwent PD initiation between March 2007 and December 2011. The PET was performed as per the standard protocol at 2 nd week and 6 th month after PD initiation. Transport status was categorized as low, low average, high average, and high as per the standard definition. There was no change in transport character in 115 patients (91.2% between the two PET measurements. When the Early PET at 2 nd week and 6 th month PET data were analyzed, no significant changes were observed in measured D/P creatinine (0.59 ± 0.14 vs. 0.62 ± 0.14 respectively P = 0.26 and D/D0 Glucose (0.46 ± 0.12 vs. 0.46 ± 0.11, P = 0.65. Using the Bland-Altman analysis the repeatability coefficients were 0.27 and 0.25 for creatinine and glucose values respectively. In our study, the PET performed at the 2 nd week are similar to that of the 6 th month PET in 91.2% of our patients and the test did not significantly change with time. In conclusion, we could do PET early at 2 nd week to assess the peritoneal membrane character and this would help in proper dialysis prescription to the patients.

  8. Comparison of peritoneal transport characteristics at the second week and at six months of peritoneal dialysis commencement.

    Science.gov (United States)

    Balasubramaniyam, R; Nirmala, V R; Yogesh, V; Sethuraman, R; Devi, S Booma; Balakrishnan, N M; Bakthavathsalam, G

    2013-09-01

    Peritoneal equilibration test (PET) is an important tool for managing peritoneal dialysis (PD) prescription. The Kidney Disease Outcomes Quality Initiative (KDOQI) guidelines suggest that the first PET be performed 4-8 weeks after PD commencement. The main reason for this delay is because of the peritoneal membrane might change its character once it is exposed to the glucose based dialysate. In this study, we compared PET 2 weeks after PD commencement to PET after 6 months to evaluate the changes in the peritoneal membrane character with time. This study included 126 patients who underwent PD initiation between March 2007 and December 2011. The PET was performed as per the standard protocol at 2(nd) week and 6(th) month after PD initiation. Transport status was categorized as low, low average, high average, and high as per the standard definition. There was no change in transport character in 115 patients (91.2%) between the two PET measurements. When the Early PET at 2(nd) week and 6(th) month PET data were analyzed, no significant changes were observed in measured D/P creatinine (0.59 ± 0.14 vs. 0.62 ± 0.14 respectively P = 0.26) and D/D0 Glucose (0.46 ± 0.12 vs. 0.46 ± 0.11, P = 0.65). Using the Bland-Altman analysis the repeatability coefficients were 0.27 and 0.25 for creatinine and glucose values respectively. In our study, the PET performed at the 2(nd) week are similar to that of the 6(th) month PET in 91.2% of our patients and the test did not significantly change with time. In conclusion, we could do PET early at 2(nd) week to assess the peritoneal membrane character and this would help in proper dialysis prescription to the patients.

  9. Old times Old times

    Directory of Open Access Journals (Sweden)

    Ubiratan Paiva de Oliveira

    2008-04-01

    Full Text Available In Pinter: A Study of His Plays, Martin Esslin mentions three levels of possible interpretation for Old Times. According to him, Pinter's play could be interpreted on a realistic level, or either representing the male character's dream or a ritual game. He correctly remarks, though, that none of those levels excludes the others, because "... they must co-exist to create the atmosphere of poetic ambivalence on which the image of the play rests..1 In Pinter: A Study of His Plays, Martin Esslin mentions three levels of possible interpretation for Old Times. According to him, Pinter's play could be interpreted on a realistic level, or either representing the male character's dream or a ritual game. He correctly remarks, though, that none of those levels excludes the others, because "... they must co-exist to create the atmosphere of poetic ambivalence on which the image of the play rests..1

  10. Five Weeks of Sprint and High-Intensity Interval Training Improves Paddling Performance in Adolescent Surfers.

    Science.gov (United States)

    Farley, Oliver R L; Secomb, Josh L; Parsonage, Joanna R; Lundgren, Lina E; Abbiss, Chris R; Sheppard, Jeremy M

    2016-09-01

    Farley, ORL, Secomb, JL, Parsonage, JR, Lundgren, LE, Abbiss, CR, and Sheppard, JM. Five weeks of sprint and high-intensity interval training improves paddling performance in adolescent surfers. J Strength Cond Res 30(9): 2446-2452, 2016-The purpose of our study was to examine the effects of sprint interval training (SIT; 10 seconds) and high-intensity interval training (HIT; 30 seconds) on surfing athletes paddling performance (400-m time trial and repeat-sprint paddle performance). Twenty-four competitive adolescent surfers (19 male, 5 female; age = 14.4 ± 1.3 years, mass: 50.1 ± 10.7 kg, and stature: 159.9 ± 10.3 cm) were assigned to perform either 5 weeks of SIT and HIT. Participants completed a repeated-sprint paddle ability test (RSPT, 15-m surfboard sprint paddle initiated every 40 seconds × 10 bouts) and 400-m endurance surfboard paddle time trial before and after training. High-intensity interval training decreased the total time to complete the 400 m by 15.8 ± 16.1 seconds (p = 0.03), and SIT decreased the total time to complete the RSPT by 6.5 ± 4.3 seconds (p = 0.02). Fatigue index during the RSPT (first-slowest effort) was lower after HIT and SIT (p ≤ 0.001 and p = 0.02, respectively). There were no significant differences in performance changes in the 400 m (total time) and RSPT (total time, fastest 15 m time, and peak velocity) between HIT and SIT. Our study indicates that HIT and SIT may be implemented to the training program of surfers to improve aerobic and repeat-sprint paddle ability, both of which are identified as key aspects of the sport. In addition, these findings indicate that 400-m paddle and RSPT can discriminate between aerobic and anaerobic training adaptations, with aerobic gains likely from HIT and anaerobic gains from SIT.

  11. Effect of sexual relationship during the last four weeks of pregnancy on Bishop score

    Directory of Open Access Journals (Sweden)

    Shayeste Esmaeelzadeh

    2008-11-01

    Full Text Available Background: Cervical favoring or ripening which is evaluated by Bishop score is an importantfactor for predicting the type of delivery, especially at the induction of labor. Higher bishop scorepredicts more vaginal delivery and reduction of cesarean. The present study is designed to assess theeffect of intercourse during the last four weeks of pregnancy on cervical ripening for giving birth.Material and Method: In this case-control study, cases were included 74 primigravid women withunriped cervix (Bishop4.The two groups were referred for vaginal delivery at term and compared based on times of intercourseand experiencing orgasm during the last four weeks of pregnancy. The data were collected byexamination and interview using a checklist.Results: Case and control group were matched based on age, job and economic situation. Meantimes of intercourse were 1.8±2.3 and 3.1±3.2 in case and control groups, respectively. Mann-Whitneyu test showed that the control group reported more intercourse than the case group in the last fourweeks of pregnancy, significantly (P<0.01, Z=2.8. In case group, 41 persons (55.4% and in thecontrol 72 persons (70.2% experienced orgasm during intercourse. This difference was alsosignificant.Conclusions: According to the results of this study, sexual relationship and orgasm in the last fourweeks of pregnancy are related to cervical favoring and so declining cesarean.

  12. RESEARCHES ON GROOMING BEHAVIOR OF THE DAMCALF COUPLE DURING THE FIRST WEEK AFTER CALVING

    Directory of Open Access Journals (Sweden)

    I. TRIPON

    2008-10-01

    Full Text Available This paper is dealing with the maternal behavior during the first week after calving. Researches were carried out during the winter season on Romanian Black and White breed dam-calf couples. The behavior of calves and their mothers was nonstop video recorded during the first, second and seventh day after calving. For a better interpretation the recorded material was divided in three periods for every 24 hours of surveillance: 07:00 to 15:00, 15:00 to 23:00, and 23:00 to 07:00. Calves received attention from their mothers in 18 to 33 grooming periods during the first day after calving. The number of grooming periods decreased to 6 – 15 periods per day in the seventh day after calving. The total length of grooming periods also decreased from the first day to the seventh day after calving from 26.5 minutes to 7.4 minutes on each 8-hour time frame. There were also contacts between mother cows and their calves that were not followed by grooming (sniffing. The number of contacts without grooming was higher during the first two days after calving and decreased on the seventh day after calving. During the first week of life calves received, 55.6 minutes per day of care from their mothers, and there were, on average, 8.1 contacts without grooming between mothers and calves.

  13. Effects of 12-week combined exercise therapy on oxidative stress in female fibromyalgia patients.

    Science.gov (United States)

    Sarıfakıoğlu, Banu; Güzelant, Aliye Yıldırım; Güzel, Eda Celik; Güzel, Savaş; Kızıler, Ali Rıza

    2014-10-01

    The aims of this study were to investigate the effect of exercise therapy on the oxidative stress in fibromyalgia patients and relationship between oxidative stress and fibromyalgia symptoms. Thirty women diagnosed with fibromyalgia according to the American College of Rheumatology preliminary criteria, and 23 healthy women whose age- and weight-matched women were enrolled the study. Pain intensity with visual analog scale (VAS), the number of tender points, the fibromyalgia impact questionnaire (FIQ), the Beck depression inventory (BDI) were evaluated. The oxidative stress parameters thiobarbituric acid reactive substances, protein carbonyls, and nitric oxide, and antioxidant parameters thiols and catalase were investigated in patients and control group. After, combined aerobic and strengthen exercise regimen was given to fibromyalgia group. Exercise therapy consisted of a warming period of 10 min, aerobic exercises period of 20 min, muscle strengthening exercises for 20 min, and 10 min cooling down period. Therapy was lasting 1 h three times per week over a 12-week period. All parameters were reevaluated after the treatment in the patient group. The oxidative stress parameters levels were significantly higher, and antioxidant parameters were significantly lower in patients with fibromyalgia than in the controls. VAS, FIQ, and BDI scores decreased significantly with exercise therapy. The exercise improved all parameters of oxidative stress and antioxidant parameters. Also, all clinical parameters were improved with exercise. We should focus on oxidative stress in the treatment for fibromyalgia with the main objective of reducing oxidative load.

  14. Six weeks of core stability training improves landing kinetics among female capoeira athletes: a pilot study.

    Science.gov (United States)

    Araujo, Simone; Cohen, Daniel; Hayes, Lawrence

    2015-03-29

    Core stability training (CST) has increased in popularity among athletes and the general fitness population despite limited evidence CST programmes alone lead to improved athletic performance. In female athletes, neuromuscular training combining balance training and trunk and hip/pelvis dominant CST is suggested to reduce injury risk, and specifically peak vertical ground reaction forces (vGRF) in a drop jump landing task. However, the isolated effect of trunk dominant core stability training on vGRF during landing in female athletes had not been evaluated. Therefore, the objective of this study was to evaluate landing kinetics during a drop jump test following a CST intervention in female capoeira athletes. After giving their informed written consent, sixteen female capoeira athletes (mean ± SD age, stature, and body mass of 27.3 ± 3.7 years, 165.0 ± 4.0 cm, and 59.7 ± 6.3 kg, respectively) volunteered to participate in the training program which consisted of static and dynamic CST sessions, three times per week for six weeks. The repeated measures T-test revealed participants significantly reduced relative vGRF from pre- to post-intervention for the first (3.40 ± 0.78 vs. 2.85 ± 0.52 N·NBW-1, respectively [pcore stability training improves landing kinetics without improving jump height, and may reduce lower extremity injury risk in female athletes.

  15. Physical comorbidity and 12-week treatment outcomes in Korean patients with depressive disorders: the CRESCEND study.

    Science.gov (United States)

    Kim, Jae-Min; Stewart, Robert; Bae, Kyung-Yeol; Yang, Su-Jin; Yoon, Jin-Sang; Jung, Sung-Won; Lee, Min-Soo; Yim, Hyeon-Woo; Jun, Tae-Youn

    2011-11-01

    Physical and depressive disorders frequently co-occur, but effects of physical health on depression treatment outcomes have received little research. This study aimed to compare treatment outcomes between people with depressive disorder with and without comorbid physical disorders. A Korean nationwide sample of 723 people with depressive disorder initiated on antidepressant treatment, and re-evaluated at 1, 2, 4, 8, and 12 weeks later. Assessment scales for evaluating depressive symptoms (HAMD), anxiety (HAMA), global severity (CGI-s), and functioning (SOFAS) were administered at baseline and every follow-up visit. Achievement of remission or response was defined only when these were maintained to the 12 weeks study endpoint or to the last follow-up examination, if earlier, with the date of the first observed remission point applied as the timing of remission. Logistic regression and Cox proportional hazards models were used. Of the sample, 247 (34%) had at least one physical disorder. This was associated with lower socioeconomic status and more severe depressive symptoms at baseline, but was not associated with any treatment related characteristics including antidepressant type and regimen, concomitant medications, side effects, and duration of treatment period. After adjustment, patients with physical comorbidity responded more slowly and less often - particularly in domains of anxiety, global severity, and functioning (all p-values depressive disorders in people with physical comorbidity. Future comparative studies between conventional and integrated treatment approaches are indicated for depressive disorders with physical comorbidity. 2011 Elsevier Inc. All rights reserved.

  16. Spectral analysis of epicardial 60-lead electrograms in dogs with 4-week-old myocardial infarction.

    Science.gov (United States)

    Hosoya, Y; Ikeda, K; Komatsu, T; Yamaki, M; Kubota, I

    2001-01-01

    There were few studies on the spectral analysis of multiple-lead epicardial electrograms in chronic myocardial infarction. Spectral analysis of multi-lead epicardial electrograms was performed in 6 sham-operated dogs (N group) and 8 dogs with 4-week-old myocardial infarction (MI group). Four weeks after the ligation of left anterior descending coronary artery, fast Fourier transform was performed on 60-lead epicardial electrograms, and then inverse transform was performed on 5 frequency ranges from 0 to 250 Hz. From the QRS onset to QRS offset, the time integration of unsigned value of reconstructed waveform was calculated and displayed as AQRS maps. On 0-25 Hz AQRS map, there was no significant difference between the 2 groups. In the frequency ranges of 25-250 Hz, MI group had significantly smaller AQRS values than N group solely in the infarct zone. It was shown that high frequency potentials (25-250 Hz) within QRS complex were reduced in the infarct zone.

  17. Monitoring of Weekly Sleep Pattern Variations at Home with a Contactless Biomotion Sensor.

    Science.gov (United States)

    Hashizaki, Masanori; Nakajima, Hiroshi; Kume, Kazuhiko

    2015-08-03

    Many people find that their sleep is restricted or disturbed by social obligations, including work. Sleep phase delays can affect an individual's circadian rhythms on the following day and cause daytime sleepiness and/or poor performance. In this study, to examine weekly variations in sleep patterns, we analyzed sleep data for seven-day periods (from Sunday to Saturday) that had been collected from 2914 subjects (aged 20-79 years) over a total of 24,899 subject-weeks using contactless biomotion sensors. On the weekend, the subjects' mean sleep midpoint, bedtime, and wake-up time were delayed by 40, 26 and 53 min, respectively, compared with those seen on weekdays. In addition, on weekdays, the mean difference between the maximum and median sleep midpoint ranged from 35 to 47 min among the subjects in their 20 s-70 s. The weekend delay and weekday variation in the subjects' sleep patterns tended to decrease with age. This study detected sleep pattern disturbances on both weekdays and weekends. The serial changes in weekday bedtimes detected in this study suggest that sleep habits are influenced by changes in the temporal patterns of social activities/duties. We need further study the advantages of getting extra sleep and the disadvantages of sleep pattern disturbances in daily lifestyle.

  18. Monitoring of Weekly Sleep Pattern Variations at Home with a Contactless Biomotion Sensor

    Directory of Open Access Journals (Sweden)

    Masanori Hashizaki

    2015-08-01

    Full Text Available Many people find that their sleep is restricted or disturbed by social obligations, including work. Sleep phase delays can affect an individual’s circadian rhythms on the following day and cause daytime sleepiness and/or poor performance. In this study, to examine weekly variations in sleep patterns, we analyzed sleep data for seven-day periods (from Sunday to Saturday that had been collected from 2914 subjects (aged 20–79 years over a total of 24,899 subject-weeks using contactless biomotion sensors. On the weekend, the subjects’ mean sleep midpoint, bedtime, and wake-up time were delayed by 40, 26 and 53 min, respectively, compared with those seen on weekdays. In addition, on weekdays, the mean difference between the maximum and median sleep midpoint ranged from 35 to 47 min among the subjects in their 20 s–70 s. The weekend delay and weekday variation in the subjects’ sleep patterns tended to decrease with age. This study detected sleep pattern disturbances on both weekdays and weekends. The serial changes in weekday bedtimes detected in this study suggest that sleep habits are influenced by changes in the temporal patterns of social activities/duties. We need further study the advantages of getting extra sleep and the disadvantages of sleep pattern disturbances in daily lifestyle.

  19. Effect of a 12-Week Physical Activity Program on Gross Motor Skills in Children.

    Science.gov (United States)

    Burns, Ryan D; Fu, You; Fang, Yi; Hannon, James C; Brusseau, Timothy A

    2017-12-01

    This study examined the effects of a 12-week Comprehensive School Physical Activity Program (CSPAP) on gross motor skill development in children from low-income families. Participants were 1,460 school-aged children (mean age = 8.4 ± 1.8 years; 730 girls, 730 boys) recruited from three schools receiving U.S. governmental financial assistance. Students were recruited from grades K-6. CSPAP was implemented over one semester during the 2014-2015 school year. Select gross motor skill items were assessed during each student's physical education class at baseline and at a 12-week follow-up using the Test for Gross Motor Development-2nd Edition (TGMD-2). Each student's TGMD-2 score was converted to a percentage of the total possible score. A 7 × 2 × 2 analysis of variance test with repeated measures was employed to examine the effects of age, sex, and time on TGMD-2 percent scores, adjusting for clustering within the data structure. There were greater TGMD-2 percent scores at follow-up compared with baseline (82.4% vs. 72.6%, mean difference = 9.8%, p < .001, Cohen's d = 0.67), and greater improvements were seen in younger children compared with older children (mean difference of change = 4.0%-7.5%, p < .01, Cohen's d = 0.30-0.55).

  20. The effect of 6-week combined agility-balance training on neuromuscular performance in basketball players.

    Science.gov (United States)

    Zemková, E; Hamar, D

    2010-09-01

    The study evaluates the effect of 6-week combined agility-balance training on neuromuscular performance in basketball players. Subjects divided into experimental (EG, n = 17) and control group (CG, n = 17) underwent a combined agility-balance training (in duration of 30 min) for a period of 6 weeks (4-5 sessions/week). Both groups performed reaction tasks similar to game-like situations, however EG on wobble boards and CG on stable surface. Prior to and after the training parameters of agility, balance, speed of step initiation, strength differentiation accuracy, and explosive power of lower limbs were evaluated. Postural stability was assessed under both static and dynamic conditions (wobble board) with eyes open and eyes closed, respectively. The velocity of the centre of pressure (COP) was registered at 100 Hz by means of posturography system FiTRO Sway check based on dynamometric platform. Using FiTRO Reaction check simple and multi-choice reaction times were measured. The same system was applied to evaluate the agility performance including reaction and movement task. Speed of step initiation was measured using FiTRO Dyne Premium. Jumping abilities were evaluated by means of FiTRO Jumper (10-seconds maximal jumps, Countermovement jump, Squat jump, Drop jump). Using the same system, the subject´s ability to match 50 % of their maximal height of the jump was evaluated. Results showed that a combined agility-balance training improved dynamic balance not only under visual control but also in eyes closed conditions. Training also increased run-out speed that likely contributed to better agility performance, reduced ground contact time during drop jump, and improved the ability to differentiate the force of muscle contraction during repeated jumps. However, such training has been found to be insufficient to improve both simple and multi-choice reaction time, and jumping performance. On the other hand, control group failed to show any significant improvement in

  1. Travel Time Reliability in Indiana

    OpenAIRE

    Martchouk, Maria; Mannering, Fred L.; Singh, Lakhwinder

    2010-01-01

    Travel time and travel time reliability are important performance measures for assessing traffic condition and extent of congestion on a roadway. This study first uses a floating car technique to assess travel time and travel time reliability on a number of Indiana highways. Then the study goes on to describe the use of Bluetooth technology to collect real travel time data on a freeway and applies it to obtain two weeks of data on Interstate 69 in Indianapolis. An autoregressive model, estima...

  2. Epidemiological and virological situation update of the 2010/2011 influenza season in the WHO European Region (Week 40/2010 to Week 03/2011)

    NARCIS (Netherlands)

    Mott, J.A.; Pereyaslov, D.; Jorgensen, P.; Brown, C.S.; Martirosyan, L.; Meerhoff, T.

    2011-01-01

    This overview of influenza data from the WHO European Region from weeks 40/2010 through week 3/2011 has been submitted for consideration during the WHO Northern Hemisphere Vaccine Strain Selection Meeting, to be held on 14-17 February, 2011, in Geneva. The 2010/2011 influenza season arrived 8-10

  3. Unexplained week-to-week variation in BNP and NT-proBNP is low in chronic heart failure patients during steady state

    DEFF Research Database (Denmark)

    Schou, Morten; Gustafsson, Finn; Nielsen, Per H

    2006-01-01

    BACKGROUND: The usefulness of brain-natriuretic-peptide (BNP) and N-terminal-pro-brain-natriuretic-peptide (NT-proBNP) for monitoring of chronic heart failure (CHF) patients has been questioned because of high levels of unexplained variation. AIMS: Week-to-week total variance (CV(T)), unexplained...

  4. Children's physical activity during a segmented school week

    DEFF Research Database (Denmark)

    Schneller, Mikkel Bo; Schipperijn, Jasper; Nielsen, Glen

    2017-01-01

    BACKGROUND: Movement integration (MI) into traditional classroom teaching is a promising opportunity for children to increase physical activity (PA). Education outside the classroom (EOtC) can be regarded as MI, and has increased children's PA in case studies. The aim of this study....... Differences in proportion of time spent in PA intensities were tested using mixed-effects regression models. RESULTS: More moderate-to-vigorous physical activity (MVPA) occurred on days with physical education (PE) than days with EOtC (girls 0.79%, p = .001, CI = .26% to 1.31%; boys 1.35%, p = .003, CI = .32......% to 2.38%), while no difference was found between EOtC days and school days without EOtC and PE. Light physical activity (LPA) was higher on EOtC days than school days without EOtC and PE (girls 2.43% p

  5. Winter fuels report week ending, March 12, 1993

    International Nuclear Information System (INIS)

    1993-01-01

    The Winter Fuels Report is intended to provide concise, timely information to the industry, the press, policymakers, consumers, analysts, and State and local governments on the following topics: distillate fuel oil net production, imports and stocks on a US level and for all Petroleum Administration for Defense Districts (PADD) and product supplied on a US level; propane net production, imports and stocks on a US level and for PADD's I, II, and III; natural gas supply and disposition and underground storage for the US and consumption for all PADD'S; as well as selected National average prices; residential and wholesale pricing data for heating oil and propane for those States participating in the joint Energy Information Administration (EIA)/State Heating Oil and Propane Program; crude oil and petroleum price comparisons for the U. S. and selected cities; and a 6-10 Day, 30-Day, and 90-Day outlook for temperature and precipitation and US total heating degree-days by city

  6. Winter Fuels Report week ending: November 8, 1991

    International Nuclear Information System (INIS)

    1991-01-01

    The Winter Fuels Report is intended to provide concise, timely information to the industry, the press, policymakers, consumers, analysts, and State and local governments on the following topics: distillate fuel oil net production, imports and stocks for all Petroleum Administration for Defense Districts (PADD) and product supplied on a US level; propane net production, imports and stocks for PADD's 1, 2, and 3; natural gas supply and disposition and underground storage for the United States and consumption for all PADD's; residential and wholesale pricing data for propane and heating oil for those States participating in the joint Energy Information Administration (EIA)/State Heating Oil and Propane Program; crude oil and petroleum price comparisons for the United States and selected cities; and US total heating degree-days by city

  7. Winter fuels report, week ending September 27, 1991

    International Nuclear Information System (INIS)

    1991-01-01

    This report is intended to provide concise, timely information to the industry, the press, policymakers, consumers, analysts, and state and local governments on the following topics: distillate fuel oil net production, imports and stocks for all Petroleum Administration for Defense Districts (PADD) and product supplied on a US level; propane net production, imports and stocks for PADD's 1, 2, 3; natural gas supply and disposition and underground storage for the United States and consumption for all PADD's; residential and wholesale pricing data for propane and heating oil for those states participating in the joint Energy Information Administration (EIA)/State Heating Oil and Propane Program; crude oil and petroleum price comparisons for the United States and selected cities; and US total heating degree-days by city. 37 figs., 13 tabs

  8. Winter fuels report, week ending October 25, 1991

    Energy Technology Data Exchange (ETDEWEB)

    1991-10-31

    The Winter Fuels Report is intended to provide concise, timely information to the industry, the press, policymakers, consumers, analysts, and state and local governments on the following topics: distillate fuel oil net production, imports and stocks for all Petroleum Administration for Defense Districts (PADD) and product supplied on a US level; propane net production, imports and stocks for PADD's 1, 2, and 3; natural gas supply and disposition and underground storage for the United States and consumption for all PADD's; residential and wholesale pricing data for propane and heating oil for those States participating in the joint Energy Information Administration (EIA)/State Heating Oil and Propane Program; crude oil and petroleum price comparisons for the United States and selected cities; and US total heating degree-days by city. 37 figs., 13 tabs.

  9. Winter Fuels Report for the week ending November 2, 1990

    Energy Technology Data Exchange (ETDEWEB)

    1990-11-08

    The report is to provide concise, timely information to the industry, the press, policymakers, consumers, analysts, and state and local governments on the following topics: distillate fuel oil net production, imports and stocks for all Petroleum Administration for Defense Districts (PADDs) and product supplied on a US level; propane net production, imports and stocks for PADD I, II, and III;natural gas supply and disposition and underground storage for the United States and consumption for all PADDs; residential and wholesale pricing data for propane and heating oil for those states participating in the joint Energy Information Administration (EIA)/State Heating Oil and Propane Program; crude oil and petroleum price comparisons for the United States and selected cities; and US total heating degree-days by city.

  10. Winter fuels report, week ending September 27, 1991. [Contains glossary

    Energy Technology Data Exchange (ETDEWEB)

    1991-10-03

    This report is intended to provide concise, timely information to the industry, the press, policymakers, consumers, analysts, and state and local governments on the following topics: distillate fuel oil net production, imports and stocks for all Petroleum Administration for Defense Districts (PADD) and product supplied on a US level; propane net production, imports and stocks for PADD's 1, 2, 3; natural gas supply and disposition and underground storage for the United States and consumption for all PADD's; residential and wholesale pricing data for propane and heating oil for those states participating in the joint Energy Information Administration (EIA)/State Heating Oil and Propane Program; crude oil and petroleum price comparisons for the United States and selected cities; and US total heating degree-days by city. 37 figs., 13 tabs.

  11. Winter fuels report, week ending October 12, 1990

    Energy Technology Data Exchange (ETDEWEB)

    1990-10-18

    The Winter Fuels Report is intended to provide concise, timely information to the industry, the press, policymakers, consumers, analysts, and state and local governments on the following topics: distillate fuel oil net production, imports and stocks for all PADD's and product supplied on a US level; propane net production, imports and stocks for Petroleum Administration for Defense Districts (PADD) I, II, and III; natural gas supply and disposition and underground storage for the United States and consumption for all PADD's; residential and wholesale pricing data for propane and heating oil for those states participating in the joint Energy Information Administration (EIA)/State Heating Oil and Propane Program; crude oil and petroleum price comparisons for the United States and selected cities; and US total heating degree-days by city.

  12. Winter fuels report, week ending November 16, 1990

    Energy Technology Data Exchange (ETDEWEB)

    1990-11-21

    The Winter Fuels Report is intended to provide concise, timely information to the industry, the press, policymakers, consumers, analysts, and State and local governments on the following topics: Distillate fuel oil net production, imports and stocks for all PADD's and product supplied on a US level; propane net production, imports and stocks for Petroleum Administration for Defense Districts (PADD) I, II, and III; natural gas supply and disposition and underground storage for the United States and consumption for all PADD's; residential and wholesale pricing data for propane and heating oil for those States participating in the joint Energy Information Administration (EIA)/State Heating Oil and Propane Program; crude oil and petroleum price comparisons for the United States and selected cities; and US total heating degree-days by city. 27 figs., 12 tabs.

  13. Winter fuels report, week ending November 9, 1990

    Energy Technology Data Exchange (ETDEWEB)

    1990-11-15

    The Winter Fuels Report is intended to provide concise, timely information to the industry, the press, policymakers, consumers, analysts, and state and local governments on the following topics: distillate fuel oil net production, imports and stocks for all PADD's and product supplied on a US level; propane net production, imports and stocks for Petroleum Administration for Defense Districts (PADD) I, II, and III; natural gas supply and disposition and underground storage for the United States and consumption for all PADD's; residential and wholesale pricing data for propane and heating oil for those states participating in the joint Energy Information Administration (EIA)/State Heating Oil and Propane Program; crude oil and petroleum price comparisons for the United States and selected cities; and US total heating degree-days by city. 27 figs., 12 tabs.

  14. Winter fuels report, week ending October 11, 1991. [Contains glossary

    Energy Technology Data Exchange (ETDEWEB)

    1991-10-17

    This Report is intended to provide concise, timely information to the industry, the press, policymakers, consumers, analysts, and State and local governments on the following topics: distillate fuel oil net production, imports and stocks for all Petroleum Administration for Defense Districts (PADD) and product supplied on a US level; propane net production, imports and stocks for PADD's 1, 2, and 3; natural gas supply and disposition and underground storage for the United States and consumption for all PADD's; residential and wholesale pricing data for propane and heating oil for those States participating in the joint Energy Information Administration (EIA)/State Heating Oil and Propane Program; crude oil and petroleum price comparisons for the United States and selected cities; and US total heating degree-days by city. 37 figs., 13 tabs.

  15. Winter fuels report, week ending October 4, 1991. [CONTAINS GLOSSARY

    Energy Technology Data Exchange (ETDEWEB)

    1991-10-10

    This report is intended to provide concise, timely information to the industry, the press, policymakers, consumers, analysts, and State and local governments on the following topics: distillate fuel oil net production, imports and stocks for all Petroleum Administration for Defense Districts (PADD) and product supplied on a US level; propane net production, imports and stocks for PADD's 1, 2, and 3; natural gas supply and disposition and underground storage for the United States and consumption for all PADD's; residential and wholesale pricing data for propane and heating oil for those States participating in the joint Energy Information Administration (EIA)/State Heating Oil and Propane Program; crude oil and petroleum price comparisons for the United States and selected cities; and US total heating degree-days by city. 37 figs., 13 tabs.

  16. Winter Fuels Report week ending: November 8, 1991

    Energy Technology Data Exchange (ETDEWEB)

    1991-11-14

    The Winter Fuels Report is intended to provide concise, timely information to the industry, the press, policymakers, consumers, analysts, and State and local governments on the following topics: distillate fuel oil net production, imports and stocks for all Petroleum Administration for Defense Districts (PADD) and product supplied on a US level; propane net production, imports and stocks for PADD's 1, 2, and 3; natural gas supply and disposition and underground storage for the United States and consumption for all PADD's; residential and wholesale pricing data for propane and heating oil for those States participating in the joint Energy Information Administration (EIA)/State Heating Oil and Propane Program; crude oil and petroleum price comparisons for the United States and selected cities; and US total heating degree-days by city.

  17. Winter fuels report, week ending October 18, 1991. [CONTAINS GLOSSARY

    Energy Technology Data Exchange (ETDEWEB)

    1991-10-24

    This report is intended to provide concise, timely information to the industry, the press, policymakers, consumers, analysts, and State and local governments on the following topics: distillate fuel oil net production, imports and stocks for all Petroleum Administration for Defense Districts (PADD) and product supplied on a US level; propane net production, imports and stocks for PADD's, 1, 2, and 3; natural gas supply and disposition and underground storage for the United States and consumption for all PADD's; residential and wholesale pricing data for propane and heating oil for those States participating in the joint Energy Information Administration (EIA)/State Heating Oil and Propane Program; crude oil and petroleum price comparisons for the United States and selected cities; and US total heating degree-days by city. 37 figs., 13 tabs.

  18. Winter fuels report: Week ending November 1, 1991

    Energy Technology Data Exchange (ETDEWEB)

    1991-11-07

    This report is intended to provide concise, timely information to the industry, the press, policymakers, consumers, analysts, and State and local governments on the following topics: distillate fuel oil net production, imports and stocks for all Petroleum Administration for Defense Districts (PADD) and product supplied on a US level; propane net production, imports and stocks for PADD's 1, 2, and 3; natural gas supply and disposition and underground storage for the United States and consumption for all PADD's; residential and wholesale pricing data for propane and heating oil for those Sates participating in the joint Energy Information Administration (EIA)/State Heating Oil and Propane Program; crude oil and petroleum price comparisons for the United States and selected cities; and US total heating degree-days by city. 37 figs., 13 tabs.

  19. Vinorelbine plus 3-weekly trastuzumab in metastatic breast cancer: a single-centre phase 2 trial

    Directory of Open Access Journals (Sweden)

    Staiano Maria

    2007-03-01

    Full Text Available Abstract Background After two studies reporting response rates higher than 70% in HER2-positive metastatic breast cancer with weekly trastuzumab and vinorelbine, we planned a phase 2 study to test activity of the same combination, with trastuzumab given every 3 weeks. Methods Patients with HER2-positive metastatic breast cancer (3+ at immunohistochemistry or positive at fluorescence in situ hybridization, PS ≤2, normal left-ventricular ejection fraction (LVEF and no more than one chemotherapy line for metastatic disease were eligible. Vinorelbine (30 mg/m2 was given on days 1&8 every 21 and trastuzumab (8 mg/kg day 1, then 6 mg/kg every 21 days. A single-stage phase 2 design, with p0 = 0.45, p1 = 0.65, type I and II error = 0.10, was applied; 22 objective responses were required in 39 patients. Results From Nov 2002 to May 2005, 50 patients were enrolled, with a median age of 54 years (range 31–81. Among 40 patients eligible for response assessment, there were 7 complete and 13 partial responses (overall response rate 50%; 95% exact CI 33.8–66.2; 11 patients had disease stabilization, lasting more than 6 months in 10 cases. Response rate did not vary according to patients and tumor characteristics, type and amount of previous chemotherapy. Within the whole series, median progression-free survival was 9.6 months (95% CI 7.3–12.3, median overall survival 22.7 months (95% CI 19.5-NA. Fifteen patients (30% developed brain metastases at a median time of 12 months (range 1–25. There was one toxic death due to renal failure in a patient receiving concomitant pamidronate. Twenty-three patients (46% had grade 3–4 neutropenia, 2 (4% grade 3 anemia, 4 (8% febrile neutropenia. Two patients stopped treatment because of grade 2 decline of LVEF and one patient because of grade 2 liver toxicity concomitant with a grade 1 decline of LVEF. One patient stopped trastuzumab after 50 cycles because of grade 1 decline of LVEF. Conclusion Although lower

  20. Multiple 60-Minute Massages per Week Offer Relief for Chronic Neck Pain

    Science.gov (United States)

    ... W X Y Z Multiple 60-Minute Massages per Week Offer Relief for Chronic Neck Pain Share: © ... funded study found that multiple 60-minute massages per week were more effective than fewer or shorter ...

  1. Old times Old times

    OpenAIRE

    Ubiratan Paiva de Oliveira

    2008-01-01

    In Pinter: A Study of His Plays, Martin Esslin mentions three levels of possible interpretation for Old Times. According to him, Pinter's play could be interpreted on a realistic level, or either representing the male character's dream or a ritual game. He correctly remarks, though, that none of those levels excludes the others, because "... they must co-exist to create the atmosphere of poetic ambivalence on which the image of the play rests..1 In Pinter: A Study of His Plays, Martin Esslin ...

  2. Effects of 1 versus 2 games a week on physical and subjective scores of subelite soccer players.

    Science.gov (United States)

    Rollo, Ian; Impellizzeri, Franco M; Zago, Matteo; Iaia, F Marcello

    2014-05-01

    The physical-performance profiles of subelite male footballers were monitored during 6 wk of a competitive season. The same squad of players played either 1 (1G, n = 15) or 2 (2G, n = 15) competitive matches per week. On weeks 0, 3, and 6, 48 h postmatch, players completed countermovement jump (CMJ), 10- and 20-m sprints, the Yo-Yo Intermittent Recovery Test (YYIRT), and the Recovery-Stress Questionnaire. Both groups undertook 2 weekly training sessions. The 2G showed after 6 wk lower YYIRT (-11% to 3%, 90% CI -15.8% to -6.8%; P m (4.4%, 1.8-6.9%; P = .007) and 20-m sprints values (4.7%, 2.9% to 6.4%; P < .001). No differences were found at 3 wk (.06 < P < .99). No changes over time (.169 < P < .611) and no differences time × group interactions (.370 < P < .550) were found for stress, recovery, and the Stress Recovery Index. In conclusion players' ability to sprint, jump, and perform repeated intense exercise was impaired when playing 2 competitive matches a week over 6 wk.

  3. Winter fuels report, week ending November 12, 1993

    Energy Technology Data Exchange (ETDEWEB)

    1993-11-18

    The Winter Fuels Report is intended to provide concise, timely information to the industry, the press, policymakers, consumers, analysts, and State and local governments on the following topics: Distillate fuel oil net production, imports and stocks on a US level and for all Petroleum Administration for Defense Districts (PADD) and product supplied on a US level; propane net production, imports and stocks on a US level and for PADD`s I, II, and III; natural gas supply and disposition and underground storage for the US and consumption for all PADD`S; as well as selected National average prices; residential and wholesale pricing data for heating oil and propane for those States participating in the joint Energy Information Administration (EIA)/State Heating Oil and Propane Program; crude oil and petroleum price comparisons for the US and selected cities; and a 6--10 Day, 30-Day, and 90-Day outlook for temperature and precipitation and US total heating degree-days by city.

  4. Winter fuels report. Week ending: January 20, 1995

    Energy Technology Data Exchange (ETDEWEB)

    1995-01-01

    The Winter Fuels Report is intended to provide concise, timely information to the industry, the press, policymakers, consumers, analysts, and State and local governments on the following topics: distillate fuel oil net production, imports and stocks on a U.S. level and for all Petroleum Administration for Defense Districts (PADD) and product supplied on a US level; propane net production, imports and stocks on a US level and for PADD`s 1, 2, and 3; natural gas supply and disposition and underground storage for the US and consumption for all PADD`s; as well as selected National average prices. Residential and wholesale pricing data for heating oil and propane for those States participating in the joint Energy Information Administration (EIA)/State Heating Oil and Propane Program; crude oil and petroleum price comparisons for the US and selected cities; and a 6--10 Day, 30-Day, and 90-Day outlook for temperature and precipitation and US total heating degree-days by city.

  5. Winter fuels report week ending, December 3, 1993

    Energy Technology Data Exchange (ETDEWEB)

    1993-12-09

    The Winter Fuels Report is intended to provide concise, timely information to the industry, the press, policymakers, consumers, analysts, and State and local governments on the following topics: distillate fuel oil net production, imports and stocks on a US level and for all Petroleum Administration for Defense Districts (PADD) and product supplied on a US level; propane net production, imports and stocks on a US level and for PADD`s I, 11, and III; natural gas supply and disposition and underground storage for the US and consumption for all PADD`S; as well as selected National average prices. residential and wholesale pricing data for heating oil and propane for those States participating in the joint Energy Information Administration (EIA)/State Heating Oil and Propane Program; crude oil and petroleum price comparisons for the US and selected cities; and a 6-10 Day, 30-Day, and 90-Day outlook for temperature and precipitation and US total heating degree-days by city.

  6. Winter fuels report. Week ending: January 19, 1996

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-01-25

    The Winter Fuels Report is intended to provide concise, timely information to the industry, the press, the policymakers, consumers, analysts, and State and local governments on the following topics: distillate fuel oil net production, imports and stocks on a US level and for all Petroleum Administration for Defense Districts (PADD) and product supplied on a US level; propane net production, imports and stocks on a US level and for PADD`s 1, 2, and 3; natural gas supply and disposition and underground storage for the US and consumption for all PADD`s, as well as selected National average prices; residential and wholesale pricing data for heating oil and propane for those States participating in the joint Energy Information Administration (EIA)/State Heating Oil and Propane Program; crude oil and petroleum price comparisons for the US and selected cities; and a 6--10 Day and 30-Day outlook for temperature and precipitation and US total heating degree-days by city. 36 figs., 13 tabs.

  7. Winter fuels report, week ending November 19, 1993

    Energy Technology Data Exchange (ETDEWEB)

    1993-11-26

    The Winter Fuels Report is intended to provide concise, timely information to the industry, the press, policymakers, consumers, analysts, and State and local governments on the following topics: Distillate fuel oil net production, imports and stocks on a US level and for all Petroleum Administration for Defense Districts (PADD) and product supplied on a US level; propane net production, imports and stocks on a US level and for PADD`s I, II, and III; natural gas supply and disposition and underground storage for the US and consumption for all PADD`S; as well as selected National average prices; residential and wholesale pricing data for heating oil and propane for those States participating in the joint Energy Information Administration (EIA)/State Heating Oil and Propane Program; crude oil and petroleum price comparisons for the US and selected cities; and a 6--10 Day, 30-Day, and 90-Day outlook for temperature and precipitation and US total heating degree-days by city.

  8. Winter fuels report week ending, February 11, 1994

    Energy Technology Data Exchange (ETDEWEB)

    1994-02-17

    The Winter Fuels Report is intended to provide concise, timely information to the industry, the press, policymakers, consumers, analysts, and State and local governments on the following topics: distillate fuel oil net production, imports and stocks on a US level and for all Petroleum Administration for Defense Districts (PADD) and product supplied on a US level; propane net production, imports and stocks on a US level and for PADD`s I, II, and III; natural gas supply and disposition and underground storage for the US and consumption for all PADD`S; as well as selected National average prices; residential and wholesale pricing data for heating oil and propane for those States participating in the joint Energy Information Administration (EIA)/State Heating Oil and Propane Program; crude oil and petroleum price comparisons for the US and selected cities; and a 6--10 Day, 30-Day, and 90-Day outlook for temperature and precipitation and US total heating degree-days by city.

  9. Winter fuels report week ending, February 4, 1994

    Energy Technology Data Exchange (ETDEWEB)

    1994-02-10

    The Winter Fuels Report is intended to provide concise, timely information to the industry, the press, policymakers, consumers, analysts, and State and local governments on the following topics: Distillate fuel oil net production, imports and stocks on a US level and for all Petroleum Administration for Defense Districts (PADD) and product supplied on a US level; Propane net production, imports and stocks on a US level and for PADD`s I, II, and III; Natural gas supply and disposition and underground storage for the US and consumption for all PADD`S (as well as selected National average prices); Residential and wholesale pricing data for heating, oil and propane for those States participating in the joint Energy Information Administration (EIA)/State Heating, Oil and Propane Program; Crude oil and petroleum price comparisons for the US and selected cities; and a 6--10 day, 30-day, and 90-day outlook for temperature and precipitation and US total heating degree-days by city.

  10. Winter fuels report. Week ending December 10, 1993

    Energy Technology Data Exchange (ETDEWEB)

    1993-12-16

    The Winter Fuels Report is intended to provide concise, timely information to the industry, the press, policymakers, consumers, analysts, and State and local governments on the following topics: distillate fuel oil net production, imports and stocks on a U.S. level and for all Petroleum Administration for Defense Districts (PADD) and product supplied on a U.S. level; propane net production, imports and stocks on a U.S. level and for PADD`s I, II, and III; natural gas supply and disposition and underground storage for the U.S. and consumption for all PADD`s; as well as selected National average prices; residential and wholesale pricing data for heating oil and propane for those States participating in the joint Energy Information Administration (EIA)/State Heating Oil and Propane Program; crude oil and petroleum price comparisons for the U.S. and selected cities; and a 6--10 Day, 30-Day, and 90-Day outlook for temperature and precipitation and U.S. total heating degree-days by city. 37 figs., 13 tabs.

  11. Start with an Hour a Week: Enhancing Usability at Wayne State University Libraries

    Directory of Open Access Journals (Sweden)

    Maria Nuccilli

    2018-01-01

    usage data to inform our initial redesign. Although we ran informal tests during the initial design process, participation was limited to library staff or student workers only. This feedback had been helpful early on, but we suspected that testing only employees may have skewed our findings. When compared to seasoned staff, many users would likely not be as familiar with library resources and website structure. The web team considered a host of research methods before embracing lean usability. We considered running focus groups, but discovered our budget rules prohibited us offering even small gift cards as compensation, generally requisite for participation in such activities. As we explored focus groups further, we also realized that the amount of preparation needed to run a session would make it hard to get regular feedback on any changes we did end up making. Hiring an expert to run the kind of large-scale user test commonly outlined in literature or outsourcing testing to a website like UserTesting.com were other methods we eliminated. We wanted a way to test users that would allow us to spend less time planning and more time testing so we could get feedback and deliver usability improvements as fast as possible. The remainder of this piece will detail our experience conducting weekly tests, and suggestions for institutions looking to begin similar testing programs,.

  12. 75 FR 20778 - Security Zone; Portland Rose Festival Fleet Week, Willamette River, Portland, OR

    Science.gov (United States)

    2010-04-21

    ...-AA87 Security Zone; Portland Rose Festival Fleet Week, Willamette River, Portland, OR AGENCY: Coast... during the Portland Rose Festival Fleet Week from June 2, 2010, through June 7, 2010. The security zone... is a need to provide a security zone for the 2010 Portland Rose Festival Fleet Week, and there is...

  13. Increased neonatal morbidity despite pulmonary maturity for deliveries occurring before 39 weeks.

    Science.gov (United States)

    Fang, Yu Ming Victor; Guirguis, Peter; Borgida, Adam; Feldman, Deborah; Ingardia, Charles; Herson, Victor

    2013-01-01

    To compare neonatal outcomes following deliveries 39 weeks after confirmation of fetal lung maturity with scheduled deliveries ≥39 weeks. A retrospective cohort study examining neonatal outcomes of women who were delivered following documented fetal pulmonary maturity at 36, 37, and 38 weeks compared to women undergoing a scheduled delivery at 39, 40, and 41 weeks. The χ(2)-test and Student's t-test were used to compare categorical and continuous data, respectively. Delivery prior to 39 weeks following fetal pulmonary maturity was associated with a 8.4% composite neonatal morbidity rate as compared to 3.3% for deliveries at 39 weeks or greater (relative risk [RR] 2.9; confidence interval [CI] 2.4-3.6). Neonatal respiratory morbidity was significantly higher (5.4%) for those delivering at less than 39 weeks with documented fetal pulmonary maturity as compared to 2.1% for those delivering at 39 weeks or greater (RR 3.0; CI 2.3-3.9). Increased neonatal morbidity persisted for those delivered prior to 39 weeks even after excluding all diabetics (p 39 weeks regardless of the mode of delivery. Despite fetal pulmonary maturity, delivery before 39 weeks is associated with significantly increased neonatal morbidity when compared to scheduled deliveries at 39 weeks or greater.

  14. 3 CFR 8454 - Proclamation 8454 of November 19, 2009. National Entrepreneurship Week, 2009

    Science.gov (United States)

    2010-01-01

    ... Entrepreneurship Week, 2009 8454 Proclamation 8454 Presidential Documents Proclamations Proclamation 8454 of November 19, 2009 Proc. 8454 National Entrepreneurship Week, 2009By the President of the United States of... risk-taking spirit. During National Entrepreneurship Week, we renew our commitment to supporting...

  15. Weekly Versus Fortnightly Cryotherapy For Warts On Extremities - A Pilot Study

    Directory of Open Access Journals (Sweden)

    Eapen Annamma

    1997-01-01

    Full Text Available Forty two patients with verruca vulgaris on the extremities who attended the Government Wenlock Hospital and KMC, Attavar, were subjected to weekly and fortnightly cryotherapy. At the end of 8 weeks, it was found that of the 37 patients who were followed up, 94% in weekly group and 84% in fortnightly group responded to treatment.

  16. Partial unilateral ureteropelvic junction obstruction induced in 2-week-old piglets

    DEFF Research Database (Denmark)

    Dissing, Thomas; Eskild-Jensen, Anni; Pagh, Christian

    2001-01-01

    of 4, 12 and 24 weeks. RESULTS: At age 4 weeks hydronephrosis was found in all obstructed kidneys included in the study. Four obstructed kidneys had renographic functional share 40% or greater and 1 deteriorated to less than 40% at 24 weeks. A total of 11 obstructed kidneys had a functional share less...

  17. 75 FR 8563 - Safety Zone; Fleet Week Maritime Festival, Pier 66, Elliott Bay, Seattle, WA

    Science.gov (United States)

    2010-02-25

    ...-AA00 Safety Zone; Fleet Week Maritime Festival, Pier 66, Elliott Bay, Seattle, WA AGENCY: Coast Guard... Fleet Week Maritime Festival. This safety zone is necessary as these events have historically resulted... the safety of life and property on navigable waters during the annual Fleet Week Maritime Festival...

  18. 3 CFR 8347 - Proclamation 8347 of February 27, 2009. National Consumer Protection Week, 2009

    Science.gov (United States)

    2010-01-01

    ... Protection Week, “Nuts & Bolts: Tools for Today’s Economy,” focuses on the basic information consumers need... Consumer Protection Week, 2009 8347 Proclamation 8347 Presidential Documents Proclamations Proclamation 8347 of February 27, 2009 Proc. 8347 National Consumer Protection Week, 2009By the President of the...

  19. Is the Four-Day School Week Detrimental to Student Success?

    Science.gov (United States)

    Tharp, Timothy W.; Matt, John; O'Reilly, Frances L.

    2016-01-01

    School districts across the United States are implementing four-day school weeks. This study looks at the relationship between student achievement in the four-day school week compared to student achievement in the five-day school week. This analysis focused on a common criteria referenced test given to all students over a period of seven years in…

  20. More with Four: A Look at the Four Day Week in Oregon's Small Schools.

    Science.gov (United States)

    Reinke, Joyce M.

    The 4-day school week offers solutions to the financial and instructional problems often faced by small rural schools. Two southern Oregon schools implemented the 4-day school week on a trial basis in 1982-83 and, along with five eastern Oregon districts, continue to use this schedule today. The primary purpose of the change to a 4-day week was…

  1. Quantitative feed restriction of Pekin breeder ducks from 3 weeks of ...

    African Journals Online (AJOL)

    0,01) lower in body mass than those restricted from 8 weeks of age. The aversion of mass loss during this period could have contributed to the improved performance recorded during the laying period. At 60 weeks of age, the ducks restricted in intake from. 3 weeks were still highly significantly (P ",;;0,01) lighter in body mass ...

  2. Fryns anophthalmia-plus syndrome in an 18-week-old fetus.

    Science.gov (United States)

    Jayasinghe, Caren; Gembruch, Ulrich; Kuchelmeister, Klaus; Körber, Friederike; Müller, Annette M

    2012-01-01

    Fryns anophthalmia-plus syndrome is a very rare condition initially described by Fryns and colleagues in 1995 in a pair of siblings of nonconsanguineous parents. Since that time, only a few cases have been reported, most of them in newborns and young children. Clinical presentation is variable and includes anophthalmia/microphthalmia, cleft lip/palate, and other facial deformities. Furthermore, skeletal, central nervous system, and endocrine anomalies have been described. We report the case of a male fetus of 18 weeks of gestation with normal karyotype and findings matching Fryns anophthalmia-plus syndrome. Pregnancy was terminated because of sonographically proven facial midline defects and a marked cerebral ventriculomegaly. Macroscopic and histological findings obtained at autopsy showed extreme bilateral microphthalmia, unilateral cleft palate, unilateral nasal deformity, and low-set ears. Skeletal anomalies included 13 pairs of ribs, premature ossification of the calcaneus, and talipes.

  3. Daily marathon running for a week-the biochemical and body compositional effects of participation

    DEFF Research Database (Denmark)

    Karstoft, Kristian; Solomon, Thomas; Laye, Matthew J

    2013-01-01

    Karstoft, K, Solomon, TP, Laye, MJ, and Pedersen, BK. Daily marathon running for a week-The biochemical and body compositional effects of participation. J Strength Cond Res 27(11): 2927-2933, 2013-Although long-distance running, such as ultramarathons and multistage races, is increasingly popular......, it maybe potentially harmful to health, despite sparse evidence. We studied 8 experienced recreational runners participating in a multiple-marathon running event in which 7 marathons were completed on consecutive days. Fasting blood chemistry and body composition were assessed before and 20-24 hours after...... the race. The total finish time for the 7 marathons ranged between 23:25:42 and 34:25:21 (hours:minutes:seconds). Only minor increases in circulating skeletal muscle cell damage markers, liver cell damage markers, and inflammatory markers occurred after the race. No other significant adverse biochemical...

  4. [Prenatal diagnosis at 25 weeks gestation and neonatal management of a vallecular cyst].

    Science.gov (United States)

    Cuillier, F; Testud, R; Samperiz, S; Fossati, P

    2002-11-01

    Due to the anatomical location, vallecular cyst is a rare but well-recognized cause of upper airway obstruction and death in newborn. This cyst can be accurately diagnosed by echography in utero and by MR imaging. Prenatal diagnosis allows for early consultation with surgical specialist, so that the time and place of the delivery can be addressed for neonatal preoperative planning. We report the first prenatal diagnosis of a vallecular cyst at 25 weeks of gestation. At birth, the cyst was drained and then marsupialized. We believed that, in cases of oropharyngeal tumors discovered in utero, elective delivery should be realised in a tertiary referral center in which emergency ventilation and tracheostomy are possible.

  5. The impact of prenatal employment on breastfeeding intentions and breastfeeding status at 1 week postpartum.

    Science.gov (United States)

    Attanasio, Laura; Kozhimannil, Katy B; McGovern, Patricia; Gjerdingen, Dwenda; Johnson, Pamela Jo

    2013-11-01

    Postpartum employment is associated with non-initiation and early cessation of breastfeeding, but less is known about the relationship between prenatal employment and breastfeeding intentions and behaviors. This study aimed to estimate the relationship between prenatal employment status, a strong predictor of postpartum return to work, and breastfeeding intentions and behaviors. Using data from the Listening to Mothers II national survey (N = 1573), we used propensity score matching methods to account for non-random selection into employment patterns and to measure the impact of prenatal employment status on breastfeeding intentions and behaviors. We also examined whether hospital practices consistent with the Baby-Friendly Hospital Initiative (BFHI), assessed based on maternal perception, were differentially associated with breastfeeding by employment status. Women who were employed (vs unemployed) during pregnancy were older, were more educated, were less likely to have had a previous cesarean delivery, and had fewer children. After matching, these differences were eliminated. Although breastfeeding intention did not differ by employment, full-time employment (vs no employment) during pregnancy was associated with decreased odds of exclusive breastfeeding 1 week postpartum (adjusted odds ratio = 0.48; 95% confidence interval, 0.25-0.92; P = .028). Higher BFHI scores were associated with higher odds of breastfeeding at 1 week but did not differentially impact women by employment status. Women employed full-time during pregnancy were less likely to fulfill their intention to exclusively breastfeed, compared to women who were not employed during pregnancy. Clinicians should be aware that employment circumstances may impact women's breastfeeding decisions; this may help guide discussions during clinical encounters.

  6. Is early rehabilitation a myth? Physical inactivity in the first week after myocardial infarction and stroke.

    Science.gov (United States)

    Lay, Sarah; Bernhardt, Julie; West, Tanya; Churilov, Leonid; Dart, Anthony; Hayes, Kate; Cumming, Toby B

    2015-12-18

    To compare physical activity levels of patients in the first week after myocardial infarction (MI) and stroke. We conducted an observational study using behavioural mapping. MI patients were consecutively recruited from Alfred Hospital, Melbourne. Data for stroke patients (Royal Perth Hospital or Austin Hospital, Melbourne) were retrieved from an existing database. Patients were observed for 1 min every 10 min from 8 am to 5 pm. At each observation, the patient's highest level of physical activity, location and people present were recorded. Details of physiotherapy and occupational therapy sessions were recorded by the therapists. Proportion of the day spent physically inactive was lower in MI (n = 32, median 48%) than stroke (n = 125, median 59%) patients, but this difference was not significant in univariate or multivariate (adjusting for age, walking ability and days post-event) regression. Time spent physically active was higher in MI (median 23%) than stroke (median 10%) patients (p = 0.009), but this difference did not survive multivariate adjustment (p = 0.67). More stroke patients (78%) than MI patients (19%) participated in therapy. This study provides the first objective data on physical activity levels of acute MI patients. While they were more active than acute stroke patients, the difference was largely attributable to walking ability. Implications for rehabilitation In the first week after myocardial infarction, patients spent about half the day physically inactive (even though 81% were able to walk independently). Similar levels of inactivity were seen in a comparable cohort of acute stroke patients, suggesting that environmental factors play an important role. There appears to be wide scope for increasing levels of physical rehabilitation after acute cardiovascular events, though optimal timing and dose remain unclear.

  7. Addressing Common Cloud-Radiation Errors from 4-hour to 4-week Model Prediction

    Science.gov (United States)

    Benjamin, S.; Sun, S.; Grell, G. A.; Green, B.; Olson, J.; Kenyon, J.; James, E.; Smirnova, T. G.; Brown, J. M.

    2017-12-01

    Cloud-radiation representation in models for subgrid-scale clouds is a known gap from subseasonal-to-seasonal models down to storm-scale models applied for forecast duration of only a few hours. NOAA/ESRL has been applying common physical parameterizations for scale-aware deep/shallow convection and boundary-layer mixing over this wide range of time and spatial scales, with some progress to be reported in this presentation. The Grell-Freitas scheme (2014, Atmos. Chem. Phys.) and MYNN boundary-layer EDMF scheme (Olson / Benjamin et al. 2016 Mon. Wea. Rev.) have been applied and tested extensively for the NOAA hourly updated 3-km High-Resolution Rapid Refresh (HRRR) and 13-km Rapid Refresh (RAP) model/assimilation systems over the United States and North America, with targeting toward improvement to boundary-layer evolution and cloud-radiation representation in all seasons. This representation is critical for both warm-season severe convective storm forecasting and for winter-storm prediction of snow and mixed precipitation. At the same time the Grell-Freitas scheme has been applied also as an option for subseasonal forecasting toward improved US week 3-4 prediction with the FIM-HYCOM coupled model (Green et al 2017, MWR). Cloud/radiation evaluation using CERES satellite-based estimates have been applied to both 12-h RAP (13km) and also during Weeks 1-4 from 32-day FIM-HYCOM (60km) forecasts. Initial results reveal that improved cloud representation is needed for both resolutions and now is guiding further refinement for cloud representation including with the Grell-Freitas scheme and with the updated MYNN-EDMF scheme (both now also in global testing as well as with the 3km HRRR and 13km RAP models).

  8. Effects of a 12-week exercise training on insulin sensitivity, quality of life, and depression status in patients with type 2 diabetes

    Directory of Open Access Journals (Sweden)

    Chia-Huei Lin

    2017-01-01

    Full Text Available Background: Exercise is one of the optimal and alternative treatments for type 2 diabetes (T2DM. Although the effect of a single bout of exercise on insulin sensitivity is reported to persist only for 2–3 days, effects remain unclear of a 12-week aerobic exercise training on insulin sensitivity, quality of life (QOL, and depression status over time as exercise training duration increases in patients with T2DM. Objectives: To investigate the effects over time in patients with T2DM of a 12-week aerobic exercise training on insulin sensitivity, QOL, and depression status. Materials and Methods: Purposive sampling was used to recruit 17 T2DM patients. Participants underwent a 12-week, supervised, moderate-intensity aerobic exercise training three times per week, 30 min per session. Outcome indicators including insulin sensitivity (measured by a 2-h oral glucose tolerance test [OGTT] and homeostatic model assessment-insulin resistance [HOMA-IR], QOL (Medical Outcomes Study Short Form 36, and depression status (beck depression inventory scale were evaluated at baseline and at 4-week intervals. Results: A final 13 eligible participants completed the study. For every 4-week increase in duration of exercise training, there was an increase over time in insulin sensitivity, including a decrease over time in OGTT glucose area under the curve of 66.92 min/mmol/L. Glucose concentrations decreased over time at 60, 90, and 120 min after an oral glucose challenge. Further, the HOMA-IR decreased over time as the duration of exercise training increased. QOL and depression status improved significantly during the training. Conclusions: Moderate-intensity exercise training improves insulin sensitivity, QOL, and depression status in T2DM patients, particularly over time within a 12-week exercise training course.

  9. Physical performance in recently aged adults after 6 weeks traditional Thai dance: a randomized controlled trial

    Directory of Open Access Journals (Sweden)

    Janyacharoen T

    2013-07-01

    Full Text Available Taweesak Janyacharoen,1–3 Maneepun Laophosri,2,4 Jaturat Kanpittaya,3,5 Paradee Auvichayapat,6 Kittisak Sawanyawisuth71School of Physical Therapy, Faculty of Associated Medical Science, Khon Kaen University, Khon Kaen, Thailand; 2Improvement of Physical Performance and Quality of Life Research Group, Khon Kaen University, Khon Kaen, Thailand; 3Back, Neck and Other Joint Pain Research Group, Khon Kaen University, Khon Kaen, Thailand; 4Department of Rehabilitation Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand; 5Department of Radiology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand; 6Department of Physiology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand; 7Department of Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, ThailandBackground: Exercise has been shown to be effective in cardiovascular endurance in the elderly. We studied the effect of Thai dancing on physical performance of Thai elderly.Methods: This was an open-labeled, randomized intervention study. The Thai dancing group exercised for 40 minutes three times a week for 6 weeks. Physical performance ability was the primary outcome, including a 6-minute walk test (6MWT, five-times sit-to-stand (FTSST, and a sit-and-reach test measured before and after 6 weeks of intervention.Results: There were 42 subjects enrolled in the study, and 38 female subjects completed (20 in Thai dance group, 18 controls, with an average age of 65.8 ± 5.1 years. The Thai dance group had significantly better physical performance in all measurements at the end of the study. The 6MWT was longer (416.7 ± 58.7 versus 345.7 ± 55.1 m; P = 0.011, FTSST was quicker (10.2 ± 1.5 versus 14.4 ± 3.3 seconds; P < 0.001, and flexibility was higher (14.9 ± 3.5 versus 11.1 ± 5.7 cm; P = 0.002 in the Thai dance group than the control group.Conclusion: Thai dance can improve physical performance in recently aged (elderly female adults

  10. Sixteen weeks of resistance training can decrease the risk of metabolic syndrome in healthy postmenopausal women

    Directory of Open Access Journals (Sweden)

    Conceição MS

    2013-09-01

    Full Text Available Miguel Soares Conceição,1 Valéria Bonganha,1 Felipe Cassaro Vechin,2 Ricardo Paes de Barros Berton,1 Manoel Emílio Lixandrão,1 Felipe Romano Damas Nogueira,1 Giovana Vergínia de Souza,1 Mara Patricia Traina Chacon-Mikahil,1 Cleiton Augusto Libardi2 1Exercise Physiology Laboratory, School of Physical Education, State University of Campinas, Campinas, 2Laboratory of Neuromuscular Adaptation to Strength Training, School of Physical Education and Sport, University of São Paulo, São Paulo, Brazil Background: The postmenopausal phase has been considered an aggravating factor for developing metabolic syndrome. Notwithstanding, no studies have as yet investigated the effects of resistance training on metabolic syndrome in postmenopausal women. Thus, the purpose of this study was to verify whether resistance training could reduce the risk of metabolic syndrome in postmenopausal women. Methods: Twenty postmenopausal women were randomly assigned to a resistance training protocol (n = 10, 53.40 ± 3.95 years, 64.58 ± 9.22 kg or a control group (n = 10, 53.0 ± 5.7 years, 64.03 ± 5.03 kg. In the resistance training protocol, ten exercises were performed, with 3 × 8–10 maximal repetitions three times per week, and the load was increased every week. Two-way analysis of variance was used to evaluate specific metabolic syndrome Z-score, high density lipoprotein cholesterol, fasting blood glucose, triglycerides, waist circumference, blood pressure, strength, and body composition. The level of statistical significance was set at P < 0.05. Results: The main results demonstrated a significant decrease of metabolic syndrome Z-score when the postmenopausal women performed resistance training (P = 0.0162. Moreover, we observed decreases in fasting blood glucose for the resistance training group (P = 0.001, and also significant improvements in lean body mass (P = 0.042, 2.46%, reduction of body fat percentage (P = 0.001, −6.75% and noticeable increases in

  11. Injuries and Associated Risk Factors Among Adolescent Elite Orienteerers: A 26-Week Prospective Registration Study

    Science.gov (United States)

    von Rosen, Philip; Heijne, Annette I.-L. M.; Frohm, Anna

    2016-01-01

    Context:  In orienteering, the number of injury-registration studies is limited. Most researchers have used a cross-sectional design during specific events and, therefore, have mainly identified acute injuries. Objective:  To determine the prevalence of injuries by registering acute and overuse injuries in adolescent elite orienteerers over 26 weeks and to study the variation of injury prevalence over the season and the potential risk factors. Design:  Cohort study. Setting:  Two high schools in Sweden with national orienteering teams. Patients or Other Participants:  All athletes (33 adolescent girls, 31 adolescent boys; age = 17 ± 1 years) from 2 high schools with orienteering teams. Main Outcome Measure(s):  We used a weekly Web-based questionnaire to identify the incidence and prevalence of injuries and training variables. Risk factors for injury were calculated using multiple linear regression techniques. Results:  The average weekly prevalence of overuse and acute injuries was 35.7% (95% confidence interval = 34.8%, 36.6%) and 1.7% (95% confidence interval = 1.3%, 2.1%), respectively; overuse injuries (78.0%, n = 85) accounted for the majority. The incidence of acute and overuse injuries was highest for the foot/lower leg (48.6%, n = 53), and 71.6% (n = 78) of all injuries affected the foot/lower leg and knee area. Time to the first reported injury was associated with training volume (β = 0.184, P = .001), competition time (β = −0.701, P = .009), running on asphalt roads (β = −0.348, P = .008), and running on forest surfaces and trails (β = −0.331, P = .007), with a model fit of r 2 = 0.50 (intercept = 2.196, P injuries in the foot/lower leg (r 2 = 0.33, P = .001); the highest prevalence (26.9%) was at the beginning of the competitive season. Conclusions:  Overuse injuries, predominately in the foot/lower leg area, were more common than acute injuries in adolescent elite orienteerers. These injuries had the highest prevalence at

  12. The effect of 8-week plyometric training on leg power, jump and sprint performance in female soccer players.

    Science.gov (United States)

    Ozbar, Nurper; Ates, Seda; Agopyan, Ani

    2014-10-01

    The aim of this study was to determine the effect of 8-week plyometric training (PT) on the leg power and jump and sprint performance in female soccer players. Eighteen female soccer players from Women Second League (age = 18.2 ± 2.3 years, height = 161.3 ± 5.4 cm, body mass = 56.6 ± 7.2 kg) were randomly assigned to control (n = 9) and plyometric (n = 9) groups. Both groups continued together with regular technical and tactical soccer training for 4 days a week. Additionally, the plyometric group underwent PT for 8 weeks, 1 day per week, 60-minute session duration. During the 8-week period, the control group was hindered from any additional conditioning training. All players' jumps (triple hop, countermovement jump, and standing broad jump), running speed (20 m), and peak power were evaluated before and after 8 weeks. No significant difference was found between the groups at pretest variables (p > 0.05). Significant improvements were found in the posttest of both the groups (p ≤ 0.05), except for 20-m sprint test in the control group (p > 0.05). Triple hop distance, countermovement jump, standing broad jump, peak power, and 20-m sprint test values were all significantly improved in the plyometric group, compared with the control group (p ≤ 0.05). We concluded that short duration PT is an improved important component of athletic performance in female soccer players. The results indicate that safe, effective, and alternative PT can be useful to strength and conditioning coaches, especially during competition season where less time is available for training.

  13. Role of young women's depression and stress symptoms in their weekly use and nonuse of contraceptive methods.

    Science.gov (United States)

    Hall, Kelli Stidham; Moreau, Caroline; Trussell, James; Barber, Jennifer

    2013-08-01

    We prospectively examined the influence of young women's depression and psychological stress symptoms on their weekly contraceptive method use. We examined data from 689 women ages 18-20 years participating in a longitudinal cohort study. Women completed 8,877 weekly journals over the first year, which assessed reproductive, relationship, and health information. We focused on baseline depression (Center for Epidemiologic Studies-Depression Scale) and stress (Perceived Stress Scale) symptoms and weekly contraceptive method use. Analyses used multivariate random effects and multinomial logistic regression. Approximately one quarter of women exhibited moderate/severe depression (27%) and stress (25%) symptoms at baseline. Contraception was not used in 10% of weekly journals, whereas coital and noncoital methods were used in 42% and 48% of weeks, respectively. In adjusted models, women with moderate/severe stress symptoms had more than twice the odds of contraception nonuse than women without stress (odds ratio [OR] 2.23, confidence interval [CI] 1.02-4.89, p = .04). Additionally, women with moderate/severe depression (RR .52, CI .40-.68, p contraceptives (OCs; reference category). Women with stress symptoms also had higher relative risks of using condoms (RR 1.17, CI 1.00-1.34, p = .02) and withdrawal (RR 1.29, CI 1.10-1.51, p = .001) than OCs. The relative risk of dual versus single method use was also lower for women with stress symptoms. Women's psychological symptoms predicted their weekly contraceptive nonuse and use of less effective methods. Further research can determine the influence of dynamic psychological symptoms on contraceptive choices and failures over time. Copyright © 2013 Society for Adolescent Health and Medicine. Published by Elsevier Inc. All rights reserved.

  14. A prospective randomized cohort study evaluating 3 weeks vs 6 weeks of oral antibiotic treatment in the setting of "maximal medical therapy" for chronic rhinosinusitis.

    Science.gov (United States)

    Sreenath, Satyan B; Taylor, Robert J; Miller, Justin D; Ambrose, Emily C; Rawal, Rounak B; Ebert, Charles S; Senior, Brent A; Zanation, Adam M

    2015-09-01

    Surprisingly, little literature exists evaluating the optimal duration of antibiotic treatment in "maximal medical therapy" for chronic rhinosinusitis (CRS). As such, we investigated whether 3 weeks vs 6 weeks of antibiotic therapy resulted in significant differences in clinical response. A prospective, randomized cohort study was performed with patients assigned to 3-week or 6-week cohorts. Our primary outcome was failure of "maximal medical therapy" and surgical recommendation. Secondary outcomes included changes in pretherapy and posttherapy scores for the Rhinosinusitis Disability Index (RSDI), Chronic Sinusitis Survey (CSS), and computed tomography (CT)-based Lund-Mackay (LM) evaluation. Analyses were substratified based on presence of nasal polyps. Forty patients were randomized to the 3-week or 6-week treatment cohorts, with near-complete clinical follow-up achieved. No significant difference was found between the proportion of patients who failed medical therapy and were deemed surgical candidates between the 2 cohorts (71% vs 68%, p = 1.000). No significant difference was found in the change of RSDI or CSS scores in the 3 vs 6 weeks of treatment groups (mean ± standard error of the mean [SEM]; RSDI: 9.62 ± 4.14 vs 1.53 ± 4.01, p = 0.868; CSS: 5.75 ± 4.36 vs 9.65 ± 5.34, p = 0.573). Last, no significant difference was found in the change of LM scores (3.35 ± 1.11 vs 1.53 ± 0.81, p = 0.829). Based on this data, there is little difference in clinical outcomes between 3 weeks vs 6 weeks of antibiotic treatment as part of "maximal medical therapy" for CRS. Increased duration of antibiotic treatment theoretically may increase risk from side effects and creates higher healthcare costs. © 2015 ARS-AAOA, LLC.

  15. A Randomized Controlled Trial of 7-Day Intensive and Standard Weekly Cognitive Therapy for PTSD and Emotion-Focused Supportive Therapy

    Science.gov (United States)

    Ehlers, Anke; Hackmann, Ann; Grey, Nick; Wild, Jennifer; Liness, Sheena; Albert, Idit; Deale, Alicia; Stott, Richard; Clark, David M.

    2014-01-01

    Objective Psychological treatments for posttraumatic stress disorder (PTSD) are usually delivered once or twice weekly over several months. It is unclear whether they can be successfully delivered over a shorter period of time. This clinical trial had two goals, (1) to investigate the acceptability and efficacy of a 7-day intensive version of cognitive therapy for PTSD, and (2) to investigate whether cognitive therapy has specific treatment effects by comparing intensive and standard weekly cognitive therapy with an equally credible alternative treatment. Method Patients with chronic PTSD (N=121) were randomly allocated to 7-day intensive or standard 3-month weekly cognitive therapy for PTSD, 3-month weekly emotion-focused supportive therapy, or a 14-week waitlist condition. Primary outcomes were PTSD symptoms and diagnosis as assessed by independent assessors and self-report. Secondary outcomes were disability, anxiety, depression, and quality of life. Measures were taken at initial assessment, 6 weeks and 14 weeks (post-treatment/wait). For groups receiving treatment, measures were also taken at 3 weeks, and follow-ups at 27 and 40 weeks after randomization. All analyses were intent-to-treat. Results At post-treatment/wait assessment, 73%, 77%, 43%, 7% of the intensive cognitive therapy, standard cognitive therapy, supportive therapy, and waitlist groups, respectively, had recovered from PTSD. All treatments were well tolerated and were superior to waitlist on all outcome measures, with the exception of no difference between supportive therapy and waitlist on quality of life. For primary outcomes, disability and general anxiety, intensive and standard cognitive therapy were superior to supportive therapy. Intensive cognitive therapy achieved faster symptom reduction and comparable overall outcomes to standard cognitive therapy. Conclusions Cognitive therapy for PTSD delivered intensively over little more than a week is as effective as cognitive therapy delivered

  16. eNAL: An Extension of the NAL Setup Correction Protocol for Effective Use of Weekly Follow-up Measurements

    International Nuclear Information System (INIS)

    Boer, Hans C.J. de; Heijmen, Ben J.M.

    2007-01-01

    Purpose: The no action level (NAL) protocol reduces systematic displacements relative to the planning CT scan by using the mean displacement of the first few treatment fractions as a setup correction in all subsequent fractions. This approach may become nonoptimal in case of time trends or transitions in the systematic displacement of a patient. Here, the extended NAL (eNAL) protocol is introduced to cope with this problem. Methods and Materials: The initial setup correction of eNAL is the same as in NAL. However, in eNAL, additional weekly follow-up measurements are performed. The setup correction is updated after each follow-up measurement based on linear regression of the available measured displacements to track and correct systematic time-dependent changes. We investigated the performance of eNAL with Monte Carlo simulations for populations without systematic displacement changes over time, with large gradual changes (time trends), and with large sudden changes (transitions). Weekly follow-up measurements were simulated for 35 treatment fractions. We compared the outcome of eNAL with NAL and optimized shrinking action level (SAL) protocol with weekly measurements. Results: Without time-dependent changes, eNAL, SAL, and NAL performed comparably, but SAL required the largest imaging workload. For time trends and transitions, eNAL performed superiorly to the other protocols and reduced systematic displacements to the same magnitude as in case of no time-dependent changes (SD ∼1 mm). Conclusion: Extended NAL can reduce systematic displacements to a minor level irrespective of the precise nature of the systematic time-dependent changes that may occur in a population

  17. Gemcitabine and cisplatin in locally advanced and metastatic bladder cancer; 3- or 4-week schedule?

    DEFF Research Database (Denmark)

    Als, Anne Birgitte; Sengeløv, Lisa; Von Der Maase, Hans

    2008-01-01

    BACKGROUND: Chemotherapy with gemcitabine and cisplatin (GC) is an active regimen in advanced transitional cell carcinoma (TCC). Traditionally, GC has been administered as a 4-week schedule. However, an alternative 3-week schedule may be more feasible. Long-term survival data for the alternative 3......-week schedule and comparisons of the feasibility and toxicity between the two schedules have not previously been published. MATERIAL AND METHODS: We performed a retrospective analysis of patients with stage IV TCC, treated with GC by a standard 4-week or by an alternative 3-week schedule. RESULTS...

  18. Effects of an 8-week yoga program on sustained attention and discrimination function in children with attention deficit hyperactivity disorder

    Directory of Open Access Journals (Sweden)

    Chien-Chih Chou

    2017-01-01

    Full Text Available This study investigated whether a yoga exercise intervention influenced the sustained attention and discrimination function in children with ADHD. Forty-nine participants (mean age = 10.50 years were assigned to either a yoga exercise or a control group. Participants were given the Visual Pursuit Test and Determination Test prior to and after an eight-week exercise intervention (twice per week, 40 min per session or a control intervention. Significant improvements in accuracy rate and reaction time of the two tests were observed over time in the exercise group compared with the control group. These findings suggest that alternative therapies such as yoga exercises can be complementary to behavioral interventions for children with attention and inhibition problems. Schools and parents of children with ADHD should consider alternatives for maximizing the opportunities that children with ADHD can engage in structured yoga  exercises.

  19. Are daily and weekly load and spot price dynamics in Australia's National Electricity Market governed by episodic nonlinearity?

    International Nuclear Information System (INIS)

    Wild, Phillip; Hinich, Melvin J.; Foster, John

    2010-01-01

    In this article, we use half hourly spot electricity prices and load data for the National Electricity Market (NEM) of Australia for the period from December 1998 to June 2009 to test for episodic nonlinearity in the dynamics governing daily and weekly cycles in load and spot price time series data. We apply the portmanteau correlation, bicorrelation and tricorrelation tests introduced in Hinich (1996) to the time series of half hourly spot prices and load demand from 7/12/1998 to 30/06/2009 using a FORTRAN 95 program. We find the presence of significant third and fourth-order (nonlinear) serial dependence in the weekly load and spot price data in particular, but to a much more marginal extent, in the daily data. (author)

  20. Effect of Prolonged Exposure Therapy Delivered Over 2 Weeks vs 8 Weeks vs Present-Centered Therapy on PTSD Symptom Severity in Military Personnel: A Randomized Clinical Trial.

    Science.gov (United States)

    Foa, Edna B; McLean, Carmen P; Zang, Yinyin; Rosenfield, David; Yadin, Elna; Yarvis, Jeffrey S; Mintz, Jim; Young-McCaughan, Stacey; Borah, Elisa V; Dondanville, Katherine A; Fina, Brooke A; Hall-Clark, Brittany N; Lichner, Tracey; Litz, Brett T; Roache, John; Wright, Edward C; Peterson, Alan L

    2018-01-23

    Effective and efficient treatment is needed for posttraumatic stress disorder (PTSD) in active duty military personnel. To examine the effects of massed prolonged exposure therapy (massed therapy), spaced prolonged exposure therapy (spaced therapy), present-centered therapy (PCT), and a minimal-contact control (MCC) on PTSD severity. Randomized clinical trial conducted at Fort Hood, Texas, from January 2011 through July 2016 and enrolling 370 military personnel with PTSD who had returned from Iraq, Afghanistan, or both. Final follow-up was July 11, 2016. Prolonged exposure therapy, cognitive behavioral therapy involving exposure to trauma memories/reminders, administered as massed therapy (n = 110; 10 sessions over 2 weeks) or spaced therapy (n = 109; 10 sessions over 8 weeks); PCT, a non-trauma-focused therapy involving identifying/discussing daily stressors (n = 107; 10 sessions over 8 weeks); or MCC, telephone calls from therapists (n = 40; once weekly for 4 weeks). Outcomes were assessed before and after treatment and at 2-week, 12-week, and 6-month follow-up. Primary outcome was interviewer-assessed PTSD symptom severity, measured by the PTSD Symptom Scale-Interview (PSS-I; range, 0-51; higher scores indicate greater PTSD severity; MCID, 3.18), used to assess efficacy of massed therapy at 2 weeks posttreatment vs MCC at week 4; noninferiority of massed therapy vs spaced therapy at 2 weeks and 12 weeks posttreatment (noninferiority margin, 50% [2.3 points on PSS-I, with 1-sided α = .05]); and efficacy of spaced therapy vs PCT at posttreatment. Among 370 randomized participants, data were analyzed for 366 (mean age, 32.7 [SD, 7.3] years; 44 women [12.0%]; mean baseline PSS-I score, 25.49 [6.36]), and 216 (59.0%) completed the study. At 2 weeks posttreatment, mean PSS-I score was 17.62 (mean decrease from baseline, 7.13) for massed therapy and 21.41 (mean decrease, 3.43) for MCC (difference in decrease, 3.70 [95% CI,0.72 to 6.68]; P = .02