WorldWideScience

Sample records for time-stamping imply collision-free

  1. Digital time stamping system based on open source technologies.

    Science.gov (United States)

    Miskinis, Rimantas; Smirnov, Dmitrij; Urba, Emilis; Burokas, Andrius; Malysko, Bogdan; Laud, Peeter; Zuliani, Francesco

    2010-03-01

    A digital time stamping system based on open source technologies (LINUX-UBUNTU, OpenTSA, OpenSSL, MySQL) is described in detail, including all important testing results. The system, called BALTICTIME, was developed under a project sponsored by the European Commission under the Program FP 6. It was designed to meet the requirements posed to the systems of legal and accountable time stamping and to be applicable to the hardware commonly used by the national time metrology laboratories. The BALTICTIME system is intended for the use of governmental and other institutions as well as personal bodies. Testing results demonstrate that the time stamps issued to the user by BALTICTIME and saved in BALTICTIME's archives (which implies that the time stamps are accountable) meet all the regulatory requirements. Moreover, the BALTICTIME in its present implementation is able to issue more than 10 digital time stamps per second. The system can be enhanced if needed. The test version of the BALTICTIME service is free and available at http://baltictime. pfi.lt:8080/btws/ and http://baltictime.lnmc.lv:8080/btws/.

  2. Authentication, Time-Stamping and Digital Signatures

    Science.gov (United States)

    Levine, Judah

    1996-01-01

    Time and frequency data are often transmitted over public packet-switched networks, and the use of this mode of distribution is likely to increase in the near future as high-speed logical circuits transmitted via networks replace point-to-point physical circuits. ALthough these networks have many technical advantages, they are susceptible to evesdropping, spoofing, and the alteration of messages enroute using techniques that are relatively simple to implement and quite difficult to detect. I will discuss a number of solutions to these problems, including the authentication mechanism used in the Network Time Protocol (NTP) and the more general technique of signing time-stamps using public key cryptography. This public key method can also be used to implement the digital analog of a Notary Public, and I will discuss how such a system could be realized on a public network such as the Internet.

  3. Time Stamp Synchronization of PEFP Distributed Control Systems

    International Nuclear Information System (INIS)

    Song, Young Gi; An, Eun Mi; Kwon, Hyeok Jung; Cho, Yong Sub

    2010-01-01

    Proton Engineering Frontier Project (PEFP) proton linac consists of several types of control systems, such as soft Input Output Controllers (IOC) and embedded IOC based on Experimental Physics Industrial Control System (EPICS) for each subsection of PEFP facility. One of the important factors is that IOC's time clock is synchronized. The synchronized time and time stamp can be achieved with Network Time Protocol (NTP) and EPICS time stamp record without timing hardware. The requirement of the time accuracy of IOCs is less than 1 second. The main objective of this study is to configure a master clock and produce Process Variable (PV) time stamps using local CPU time synchronized from the master clock. The distributed control systems are attached on PEFP control network

  4. Extracting Hot spots of Topics from Time Stamped Documents

    Science.gov (United States)

    Chen, Wei; Chundi, Parvathi

    2011-01-01

    Identifying time periods with a burst of activities related to a topic has been an important problem in analyzing time-stamped documents. In this paper, we propose an approach to extract a hot spot of a given topic in a time-stamped document set. Topics can be basic, containing a simple list of keywords, or complex. Logical relationships such as and, or, and not are used to build complex topics from basic topics. A concept of presence measure of a topic based on fuzzy set theory is introduced to compute the amount of information related to the topic in the document set. Each interval in the time period of the document set is associated with a numeric value which we call the discrepancy score. A high discrepancy score indicates that the documents in the time interval are more focused on the topic than those outside of the time interval. A hot spot of a given topic is defined as a time interval with the highest discrepancy score. We first describe a naive implementation for extracting hot spots. We then construct an algorithm called EHE (Efficient Hot Spot Extraction) using several efficient strategies to improve performance. We also introduce the notion of a topic DAG to facilitate an efficient computation of presence measures of complex topics. The proposed approach is illustrated by several experiments on a subset of the TDT-Pilot Corpus and DBLP conference data set. The experiments show that the proposed EHE algorithm significantly outperforms the naive one, and the extracted hot spots of given topics are meaningful. PMID:21765568

  5. Welding Robot Collision-Free Path Optimization

    Directory of Open Access Journals (Sweden)

    Xuewu Wang

    2017-02-01

    Full Text Available Reasonable welding path has a significant impact on welding efficiency, and a collision-free path should be considered first in the process of welding robot path planning. The shortest path length is considered as an optimization objective, and obstacle avoidance is considered as the constraint condition in this paper. First, a grid method is used as a modeling method after the optimization objective is analyzed. For local collision-free path planning, an ant colony algorithm is selected as the search strategy. Then, to overcome the shortcomings of the ant colony algorithm, a secondary optimization is presented to improve the optimization performance. Finally, the particle swarm optimization algorithm is used to realize global path planning. Simulation results show that the desired welding path can be obtained based on the optimization strategy.

  6. Time-stamping system for nuclear physics experiments at RIKEN RIBF

    International Nuclear Information System (INIS)

    Baba, H.; Ichihara, T.; Ohnishi, T.; Takeuchi, S.; Yoshida, K.; Watanabe, Y.; Ota, S.; Shimoura, S.; Yoshinaga, K.

    2015-01-01

    A time-stamping system for nuclear physics experiments has been introduced at the RIKEN Radioactive Isotope Beam Factory. Individual trigger signals can be applied for separate data acquisition (DAQ) systems. After the measurements are complete, separately taken data are merged based on the time-stamp information. In a typical experiment, coincidence trigger signals are formed from multiple detectors to take desired events only. The time-stamping system allows the use of minimum bias triggers. Since coincidence conditions are given by software, a variety of physics events can be flexibly identified. The live time for a DAQ system is important when attempting to determine reaction cross-sections. However, the combined live time for separate DAQ systems is not clearly known because it depends not only on the DAQ dead time but also on the coincidence conditions. Using the proposed time-stamping system, all trigger timings can be acquired, so that the combined live time can be easily determined. The combined live time is also estimated using Monte Carlo simulations, and the results are compared with the directly measured values in order to assess the accuracy of the simulation

  7. Impact of Electronic Signatures and Time Stamping for the Protection of Electronic Agreements

    Directory of Open Access Journals (Sweden)

    Tadas Limba

    2012-12-01

    Full Text Available The article e495 valuates the impact of e-signatures and time stamping on electronic contracts and electronic documents for performing e-business opportunities and goals, and analyses e-signature application for business cases. Various electronic services, virtual shopping, electronic cash transactions are becoming increasingly popular as they allow users to quickly perform different actions, operations and functions. It is important not only for convenience, but also to ensure consumer data security and reliability. Security reasons are not enough for security transmitted data, since this method does not allow clarification of information about sender identity.Use of electronic signatures, electronic identities, checgs and ensures a very high level of data security in interchange data processes. E-signature allows e-business companies to transfer the company’s operation business processes and their application to the organization and management in the electronic environment, also automate internal and external compans processes, includinggon-going business processes.The object of paper is .-signature and time stamping application in the theoretical and practical way.The goal of this paper while evaluating and estimating the .-signature and time stamping application, i’s regulation and legal implementation worldwidesand in Lithuania—is to provideluseful recommendations for more efficient impact developing -commerce and -business in situations when -signature and time stamping is used for ensuring electronic contracs security.

  8. Impact of Electronic Signatures and Time Stamping for the Protection of Electronic Agreements

    Directory of Open Access Journals (Sweden)

    Tadas Limba

    2013-02-01

    Full Text Available The article e495 valuates the impact of e-signatures and time stamping on electronic contracts and electronic documents for performing e-business opportunities and goals, and analyses e-signature application for business cases. Various electronic services, virtual shopping, electronic cash transactions are becoming increasingly popular as they allow users to quickly perform different actions, operations and functions. It is important not only for convenience, but also to ensure consumer data security and reliability. Security reasons are not enough for security transmitted data, since this method does not allow clarification of information about sender identity. Use of electronic signatures, electronic identities, checgs and ensures a very high level of data security in interchange data processes. E-signature allows e-business companies to transfer the company’s operation business processes and their application to the organization and management in the electronic environment, also automate internal and external compans processes, includinggon-going business processes. The object of paper is .-signature and time stamping application in the theoretical and practical way. The goal of this paper while evaluating and estimating the .-signature and time stamping application, i’s regulation and legal implementation worldwidesand in Lithuania—is to provideluseful recommendations for more efficient impact developing -commerce and -business in situations when -signature and time stamping is used for ensuring electronic contracs security.

  9. Time stamp technique using a nuclear emulsion multi-stage shifter for gamma-ray telescope

    International Nuclear Information System (INIS)

    Takahashi, Satoru; Aoki, Shigeki; Rokujo, Hiroki; Hamada, Kaname; Komatsu, Masahiro; Morishima, Kunihiro; Nakamura, Mitsuhiro; Nakano, Toshiyuki; Niwa, Kimio; Sato, Osamu; Yoshioka, Teppei; Kodama, Koichi

    2010-01-01

    Nuclear emulsion has a potential use as a gamma-ray telescope with high angular resolution. For this application it is necessary to know the time when each track was recorded in the emulsion. In previous experiments using nuclear emulsion, various efforts were used to associate time to nuclear emulsion tracks and to improve the time resolution. Using a high speed readout system for nuclear emulsion together with a clock-based multi-stage emulsion shifter, we invented a technique to give a time-stamp to emulsion tracks and greatly improve the time resolution. A test experiment with a 2-stage shifter was used to demonstrate the principle of multi-stage shifting, and we achieved a time resolution 1.5 s for 12.1 h (about 1 part in 29 000) with the time stamp reliability 97% and the time stamp efficiency 98%. This multi-stage shifter can achieve the time resolution required for a gamma-ray telescope and can also be applied to another cosmic ray observations and accelerator experiments using nuclear emulsion.

  10. Time stamp generation with inverse FIR filters for Positron Emission Tomography

    International Nuclear Information System (INIS)

    Namias, Mauro

    2009-01-01

    Photon coincidence detection is the process by which Positron Emission Tomography (PET) works. This requires the determination of the time of impact of each coincident photon at the detector system, also known as time stamp. In this work, the timestamp was generated by means of digital time-domain deconvolution with FIR filters for a INa(Tl) based system. The detector deadtime was reduced from 350 ns to 175 ns while preserving the system's energy resolution and a direct relation between the amount of light collected and the temporal resolution was found.(author)

  11. Construction of Time-Stamped Mobility Map for Path Tracking via Smith-Waterman Measurement Matching

    Directory of Open Access Journals (Sweden)

    Mu Zhou

    2014-01-01

    Full Text Available Path tracking in wireless and mobile environments is a fundamental technology for ubiquitous location-based services (LBSs. In particular, it is very challenging to develop highly accurate and cost-efficient tracking systems applied to the anonymous areas where the floor plans are not available for security and privacy reasons. This paper proposes a novel path tracking approach for large Wi-Fi areas based on the time-stamped unlabeled mobility map which is constructed from Smith-Waterman received signal strength (RSS measurement matching. Instead of conventional location fingerprinting, we construct mobility map with the technique of dimension reduction from the raw measurement space into a low-dimensional embedded manifold. The feasibility of our proposed approach is verified by the real-world experiments in the HKUST campus Wi-Fi networks, sMobileNet. The experimental results prove that our approach is adaptive and capable of achieving an adequate precision level in path tracking.

  12. Time-stamp correction of magnetic observatory data acquired during unavailability of time-synchronization services

    Science.gov (United States)

    Coïsson, Pierdavide; Telali, Kader; Heumez, Benoit; Lesur, Vincent; Lalanne, Xavier; Jiang Xin, Chang

    2017-09-01

    During magnetic observatory data acquisition, the data time stamp is kept synchronized with a precise source of time. This is usually done using a GPS-controlled pulse per second (PPS) signal. For some observatories located in remote areas or where internet restrictions are enforced, only the magnetometer data are transmitted, limiting the capabilities of monitoring the acquisition operations. The magnetic observatory in Lanzhou (LZH), China, experienced an unnoticed interruption of the GPS PPS starting 7 March 2013. The data logger clock drifted slowly in time: in 6 months a lag of 27 s was accumulated. After a reboot on 2 April 2014 the drift became faster, -2 s per day, before the GPS PPS could be restored on 8 July 2014. To estimate the time lags that LZH time series had accumulated, we compared it with data from other observatories located in East Asia. A synchronization algorithm was developed. Natural sources providing synchronous events could be used as markers to obtain the time lag between the observatories. The analysis of slices of 1 h of 1 s data at arbitrary UTC allowed estimating time lags with an uncertainty of ˜ 11 s, revealing the correct trends of LZH time drift. A precise estimation of the time lag was obtained by comparing data from co-located instruments controlled by an independent PPS. In this case, it was possible to take advantage of spikes and local noise that constituted precise time markers. It was therefore possible to determine a correction to apply to LZH time stamps to correct the data files and produce reliable 1 min averaged definitive magnetic data.

  13. Recognition of Time Stamps on Full-Disk Hα Images Using Machine Learning Methods

    Science.gov (United States)

    Xu, Y.; Huang, N.; Jing, J.; Liu, C.; Wang, H.; Fu, G.

    2016-12-01

    Observation and understanding of the physics of the 11-year solar activity cycle and 22-year magnetic cycle are among the most important research topics in solar physics. The solar cycle is responsible for magnetic field and particle fluctuation in the near-earth environment that have been found increasingly important in affecting the living of human beings in the modern era. A systematic study of large-scale solar activities, as made possible by our rich data archive, will further help us to understand the global-scale magnetic fields that are closely related to solar cycles. The long-time-span data archive includes both full-disk and high-resolution Hα images. Prior to the widely use of CCD cameras in 1990s, 35-mm films were the major media to store images. The research group at NJIT recently finished the digitization of film data obtained by the National Solar Observatory (NSO) and Big Bear Solar Observatory (BBSO) covering the period of 1953 to 2000. The total volume of data exceeds 60 TB. To make this huge database scientific valuable, some processing and calibration are required. One of the most important steps is to read the time stamps on all of the 14 million images, which is almost impossible to be done manually. We implemented three different methods to recognize the time stamps automatically, including Optical Character Recognition (OCR), Classification Tree and TensorFlow. The latter two are known as machine learning algorithms which are very popular now a day in pattern recognition area. We will present some sample images and the results of clock recognition from all three methods.

  14. Design and implementation of a nanosecond time-stamping readout system-on-chip for photo-detectors

    International Nuclear Information System (INIS)

    Anvar, Shebli; Château, Frédéric; Le Provost, Hervé; Louis, Frédéric; Manolopoulos, Konstantinos; Moudden, Yassir; Vallage, Bertrand; Zonca, Eric

    2014-01-01

    A readout system suitable for a large number of synchronized photo-detection units has been designed. Each unit embeds a specifically designed fully integrated communicating system based on Xilinx FPGA SoC technology. It runs the VxWorks real-time OS and a custom data acquisition software designed within the Ice middleware framework, resulting in a highly flexible, controllable and scalable distributed application. Clock distribution and delay calibration over customized fixed latency gigabit Ethernet links enable synchronous time-stamping of events with nanosecond precision. The implementation of this readout system on several data-collecting units as well as its performances are described

  15. Sensor Fusion Based Model for Collision Free Mobile Robot Navigation

    Science.gov (United States)

    Almasri, Marwah; Elleithy, Khaled; Alajlan, Abrar

    2015-01-01

    Autonomous mobile robots have become a very popular and interesting topic in the last decade. Each of them are equipped with various types of sensors such as GPS, camera, infrared and ultrasonic sensors. These sensors are used to observe the surrounding environment. However, these sensors sometimes fail and have inaccurate readings. Therefore, the integration of sensor fusion will help to solve this dilemma and enhance the overall performance. This paper presents a collision free mobile robot navigation based on the fuzzy logic fusion model. Eight distance sensors and a range finder camera are used for the collision avoidance approach where three ground sensors are used for the line or path following approach. The fuzzy system is composed of nine inputs which are the eight distance sensors and the camera, two outputs which are the left and right velocities of the mobile robot’s wheels, and 24 fuzzy rules for the robot’s movement. Webots Pro simulator is used for modeling the environment and the robot. The proposed methodology, which includes the collision avoidance based on fuzzy logic fusion model and line following robot, has been implemented and tested through simulation and real time experiments. Various scenarios have been presented with static and dynamic obstacles using one robot and two robots while avoiding obstacles in different shapes and sizes. PMID:26712766

  16. Collision-free gases in spatially homogeneous space-times

    International Nuclear Information System (INIS)

    Maartens, R.; Maharaj, S.D.

    1985-01-01

    The kinematical and dynamical properties of one-component collision-free gases in spatially homogeneous, locally rotationally symmetric (LRS) space-times are analyzed. Following Ray and Zimmerman [Nuovo Cimento B 42, 183 (1977)], it is assumed that the distribution function f of the gas inherits the symmetry of space-time, in order to construct solutions of Liouville's equation. The redundancy of their further assumption that f be based on Killing vector constants of the motion is shown. The Ray and Zimmerman results for Kantowski--Sachs space-time are extended to all spatially homogeneous LRS space-times. It is shown that in all these space-times the kinematic average four-velocity u/sup i/ can be tilted relative to the homogeneous hypersurfaces. This differs from the perfect fluid case, in which only one space-time admits tilted u/sup i/, as shown by King and Ellis [Commun. Math. Phys. 31, 209 (1973)]. As a consequence, it is shown that all space-times admit nonzero acceleration and heat flow, while a subclass admits nonzero vorticity. The stress π/sub i/j is proportional to the shear sigma/sub i/j by virtue of the invariance of the distribution function. The evolution of tilt and the existence of perfect fluid solutions is also discussed

  17. Sensor Fusion Based Model for Collision Free Mobile Robot Navigation

    Directory of Open Access Journals (Sweden)

    Marwah Almasri

    2015-12-01

    Full Text Available Autonomous mobile robots have become a very popular and interesting topic in the last decade. Each of them are equipped with various types of sensors such as GPS, camera, infrared and ultrasonic sensors. These sensors are used to observe the surrounding environment. However, these sensors sometimes fail and have inaccurate readings. Therefore, the integration of sensor fusion will help to solve this dilemma and enhance the overall performance. This paper presents a collision free mobile robot navigation based on the fuzzy logic fusion model. Eight distance sensors and a range finder camera are used for the collision avoidance approach where three ground sensors are used for the line or path following approach. The fuzzy system is composed of nine inputs which are the eight distance sensors and the camera, two outputs which are the left and right velocities of the mobile robot’s wheels, and 24 fuzzy rules for the robot’s movement. Webots Pro simulator is used for modeling the environment and the robot. The proposed methodology, which includes the collision avoidance based on fuzzy logic fusion model and line following robot, has been implemented and tested through simulation and real time experiments. Various scenarios have been presented with static and dynamic obstacles using one robot and two robots while avoiding obstacles in different shapes and sizes.

  18. Vertically integrated deep N-well CMOS MAPS with sparsification and time stamping capabilities for thin charged particle trackers

    International Nuclear Information System (INIS)

    Ratti, L.; Gaioni, L.; Manghisoni, M.; Re, V.; Traversi, G.

    2010-01-01

    A fine pitch, deep N-well CMOS monolithic active pixel sensor (DNW CMOS MAPS) with sparsified readout architecture and time stamping capabilities has been designed in a vertical integration (3D) technology. In this process, two 130 nm CMOS wafers are face-to-face bonded by means of thermo-compression techniques ensuring both the mechanical stability of the structure and the electrical interconnection between circuits belonging to different layers. This 3D design represents the evolution of a DNW monolithic sensor already fabricated in a planar 130 nm CMOS technology in view of applications to the vertex detector of the International Linear Collider (ILC). The paper is devoted to discussing the main design features and expected performance of the 3D DNW MAPS. Besides describing the front-end circuits and the general architecture of the detector, the work also provides some results from calculations and Monte Carlo device simulations comparing the old 2D solution with the new 3D one and illustrating the attainable detection efficiency improvements.

  19. Vertically integrated deep N-well CMOS MAPS with sparsification and time stamping capabilities for thin charged particle trackers

    Energy Technology Data Exchange (ETDEWEB)

    Ratti, L., E-mail: lodovico.ratti@unipv.i [Universita di Pavia, Dipartimento di Elettronica, Via Ferrata 1, I-27100 Pavia (Italy); INFN, Sezione di Pavia, Via Bassi 6, I-27100 Pavia (Italy); Gaioni, L. [Universita di Pavia, Dipartimento di Elettronica, Via Ferrata 1, I-27100 Pavia (Italy); INFN, Sezione di Pavia, Via Bassi 6, I-27100 Pavia (Italy); Manghisoni, M.; Re, V.; Traversi, G. [Universita di Bergamo, Dipartimento di Ingegneria Industriale, Via Marconi 5, I-24044 Dalmine (Bulgaria) (Italy); INFN, Sezione di Pavia, Via Bassi 6, I-27100 Pavia (Italy)

    2010-12-11

    A fine pitch, deep N-well CMOS monolithic active pixel sensor (DNW CMOS MAPS) with sparsified readout architecture and time stamping capabilities has been designed in a vertical integration (3D) technology. In this process, two 130 nm CMOS wafers are face-to-face bonded by means of thermo-compression techniques ensuring both the mechanical stability of the structure and the electrical interconnection between circuits belonging to different layers. This 3D design represents the evolution of a DNW monolithic sensor already fabricated in a planar 130 nm CMOS technology in view of applications to the vertex detector of the International Linear Collider (ILC). The paper is devoted to discussing the main design features and expected performance of the 3D DNW MAPS. Besides describing the front-end circuits and the general architecture of the detector, the work also provides some results from calculations and Monte Carlo device simulations comparing the old 2D solution with the new 3D one and illustrating the attainable detection efficiency improvements.

  20. The Concept of Collision-Free Motion Planning Using a Dynamic Collision Map

    Directory of Open Access Journals (Sweden)

    Keum-Bae Cho

    2014-09-01

    Full Text Available In this paper, we address a new method for the collision-free motion planning of a mobile robot in dynamic environments. The motion planner is based on the concept of a conventional collision map (CCM, represented on the L(travel length-T(time plane. We extend the CCM with dynamic information about obstacles, such as linear acceleration and angular velocity, providing useful information for estimating variation in the collision map. We first analyse the effect of the dynamic motion of an obstacle in the collision region. We then define the measure of collision dispersion (MOCD. The dynamic collision map (DCM is generated by drawing the MOCD on the CCM. To evaluate a collision-free motion planner using the DCM, we extend the DCM with MOCD, then draw the unreachable region and deadlocked regions. Finally, we construct a collision-free motion planner using the information from the extended DCM.

  1. Collision free path generation in 3D with turning and pitch radius constraints for aerial vehicles

    DEFF Research Database (Denmark)

    Schøler, F.; La Cour-Harbo, A.; Bisgaard, M.

    2009-01-01

    In this paper we consider the problem of trajectory generation in 3D for uninhabited aerial systems (UAS). The proposed algorithm for trajectory generation allows us to find a feasible collision-free 3D trajectory through a number of waypoints in an environment containing obstacles. Our approach...... assumes that most of the aircraft structural and dynamic limitations can be formulated as a turn radius constraint, and that any two consecutive waypoints have line-of-sight. The generated trajectories are collision free and also satisfy a constraint on the minimum admissible turning radius, while...

  2. Collision-Free Structure Using Thin-Film Magnet For Electrostatic Energy Harvester

    International Nuclear Information System (INIS)

    Yoshii, S; Yamaguchi, K; Fujita, T; Kanda, K; Maenaka, K

    2016-01-01

    This paper proposes collision-free structure using NdFeB thin-film magnet for vibration energy harvesters. By using stripe shaped NdFeB magnet array on the Si MEMS structure, we finally obtained 3 mN of magnetic repulsive force on 8 × 8 mm 2 specimen with 40 μm air-gap. (paper)

  3. Collision-Free Structure Using Thin-Film Magnet For Electrostatic Energy Harvester

    Science.gov (United States)

    Yoshii, S.; Yamaguchi, K.; Fujita, T.; Kanda, K.; Maenaka, K.

    2016-11-01

    This paper proposes collision-free structure using NdFeB thin-film magnet for vibration energy harvesters. By using stripe shaped NdFeB magnet array on the Si MEMS structure, we finally obtained 3 mN of magnetic repulsive force on 8 × 8 mm2 specimen with 40 μm air-gap.

  4. Towards a Collision-Free WLAN: Dynamic Parameter Adjustment in CSMA/E2CA

    Directory of Open Access Journals (Sweden)

    Bellalta Boris

    2011-01-01

    Full Text Available Carrier sense multiple access with enhanced collision avoidance (CSMA/ECA is a distributed MAC protocol that allows collision-free access to the medium in WLANs. The only difference between CSMA/ECA and the well-known CSMA/CA is that the former uses a deterministic backoff after successful transmissions. Collision-free operation is reached after a transient state during which some collisions may occur. This paper shows that the duration of the transient state can be shortened by appropriately setting the contention parameters. Standard absorbing Markov chain theory is used to describe the behaviour of the system in the transient state and to predict the expected number of slots to reach the collision-free operation. The paper also introduces CSMA/E2CA, in which a deterministic backoff is used two consecutive times after a successful transmission. CSMA/E2CA converges quicker to collision-free operation and delivers higher performance than CSMA/ECA, specially in harsh wireless scenarios with high frame-error rates. The last part of the paper addresses scenarios with a large number of contenders. We suggest dynamic parameter adjustment techniques to accommodate a varying (and potentially high number of contenders. The effectiveness of these adjustments in preventing collisions is validated by means of simulation.

  5. Normalization for Implied Volatility

    OpenAIRE

    Fukasawa, Masaaki

    2010-01-01

    We study specific nonlinear transformations of the Black-Scholes implied volatility to show remarkable properties of the volatility surface. Model-free bounds on the implied volatility skew are given. Pricing formulas for the European options which are written in terms of the implied volatility are given. In particular, we prove elegant formulas for the fair strikes of the variance swap and the gamma swap.

  6. A Collision-Free G2 Continuous Path-Smoothing Algorithm Using Quadratic Polynomial Interpolation

    Directory of Open Access Journals (Sweden)

    Seong-Ryong Chang

    2014-12-01

    Full Text Available Most path-planning algorithms are used to obtain a collision-free path without considering continuity. On the other hand, a continuous path is needed for stable movement. In this paper, the searched path was converted into a G2 continuous path using the modified quadratic polynomial and membership function interpolation algorithm. It is simple, unique and provides a good geometric interpretation. In addition, a collision-checking and improvement algorithm is proposed. The collision-checking algorithm can check the collisions of a smoothed path. If collisions are detected, the collision improvement algorithm modifies the collision path to a collision-free path. The collision improvement algorithm uses a geometric method. This method uses the perpendicular line between a collision position and the collision piecewise linear path. The sub-waypoint is added, and the QPMI algorithm is applied again. As a result, the collision-smoothed path is converted into a collision-free smooth path without changing the continuity.

  7. A general dead-time correction method based on live-time stamping. Application to the measurement of short-lived radionuclides.

    Science.gov (United States)

    Chauvenet, B; Bobin, C; Bouchard, J

    2017-12-01

    Dead-time correction formulae are established in the general case of superimposed non-homogeneous Poisson processes. Based on the same principles as conventional live-timed counting, this method exploits the additional information made available using digital signal processing systems, and especially the possibility to store the time stamps of live-time intervals. No approximation needs to be made to obtain those formulae. Estimates of the variances of corrected rates are also presented. This method is applied to the activity measurement of short-lived radionuclides. Copyright © 2017 Elsevier Ltd. All rights reserved.

  8. A new approach for improved time and position measurements for TOF-PET: Time-stamping of the photo-electrons using analogue SiPMs

    Energy Technology Data Exchange (ETDEWEB)

    Doroud, K., E-mail: Katayoun.Doroud@cern.ch [CERN Geneva (Switzerland); Williams, M.C.S. [CERN Geneva (Switzerland); INFN, Bologna (Italy)

    2017-03-21

    Measurement of the Time-of-Flight (TOF) of the 511 keV gammas brings an important reduction of statistical noise in the PET image, with higher precision time measurements producing clearer images. The common method of coupling a photodetector to scintillating crystals is to have two matching matrices, with a one-to-one coupling between the crystal and the photodetector. We propose a new geometry based on analogue strip SiPMs reading out a scintillator cut into slabs. This technique allows the time stamping of individual photo-electrons and extracts the best time resolution using a specific algorithm. Here we present the results from the first ‘slab module’ test.

  9. A new approach for improved time and position measurements for TOF-PET: Time-stamping of the photo-electrons using analogue SiPMs

    CERN Document Server

    Doroud, K

    2017-01-01

    Measurement of the Time-of-Flight (TOF) of the 511 keV gammas brings an important reduction of statistical noise in the PET image, with higher precision time measurements producing clearer images. The common method of coupling a photodetector to scintillating crystals is to have two matching matrices, with a one-to-one coupling between the crystal and the photodetector. We propose a new geometry based on analogue strip SiPMs reading out a scintillator cut into slabs. This technique allows the time stamping of individual photo-electrons and extracts the best time resolution using a specific algorithm. Here we present the results from the first ‘slab module’ test.

  10. Numerical simulation of collision-free plasma using Vlasov hybrid simulation

    International Nuclear Information System (INIS)

    Nunn, D.

    1990-01-01

    A novel scheme for the numerical simulation of wave particle interactions in space plasmas has been developed. The method, termed VHS or Vlasov Hybrid Simulation, is applicable to hot collision free plasmas in which the unperturbed distribution functions is smooth and free of delta function singularities. The particle population is described as a continuous Vlasov fluid in phase space-granularity and collisional effects being ignored. In traditional PIC/CIC codes the charge/current due to each simulation particle is assigned to a fixed spatial grid. In the VHS method the simulation particles sample the Vlasov fluid and provide information about the value of distribution function (F(r,v) at random points in phase space. Values of F are interpolated from the simulation particles onto a fixed grid in velocity/position or phase space. With distribution function defined on a phase space grid the plasma charge/current field is quickly calculated. The simulation particles serve only to provide information, and thus the particle population may be dynamic. Particles no longer resonant with the wavefield may be discarded from the simulation, and new particles may be inserted into the Vlasov fluid where required

  11. Autonomous Collision-Free Navigation of Microvehicles in Complex and Dynamically Changing Environments.

    Science.gov (United States)

    Li, Tianlong; Chang, Xiaocong; Wu, Zhiguang; Li, Jinxing; Shao, Guangbin; Deng, Xinghong; Qiu, Jianbin; Guo, Bin; Zhang, Guangyu; He, Qiang; Li, Longqiu; Wang, Joseph

    2017-09-26

    Self-propelled micro- and nanoscale robots represent a rapidly emerging and fascinating robotics research area. However, designing autonomous and adaptive control systems for operating micro/nanorobotics in complex and dynamically changing environments, which is a highly demanding feature, is still an unmet challenge. Here we describe a smart microvehicle for precise autonomous navigation in complicated environments and traffic scenarios. The fully autonomous navigation system of the smart microvehicle is composed of a microscope-coupled CCD camera, an artificial intelligence planner, and a magnetic field generator. The microscope-coupled CCD camera provides real-time localization of the chemically powered Janus microsphere vehicle and environmental detection for path planning to generate optimal collision-free routes, while the moving direction of the microrobot toward a reference position is determined by the external electromagnetic torque. Real-time object detection offers adaptive path planning in response to dynamically changing environments. We demonstrate that the autonomous navigation system can guide the vehicle movement in complex patterns, in the presence of dynamically changing obstacles, and in complex biological environments. Such a navigation system for micro/nanoscale vehicles, relying on vision-based close-loop control and path planning, is highly promising for their autonomous operation in complex dynamic settings and unpredictable scenarios expected in a variety of realistic nanoscale scenarios.

  12. A traffic priority language for collision-free navigation of autonomous mobile robots in dynamic environments.

    Science.gov (United States)

    Bourbakis, N G

    1997-01-01

    This paper presents a generic traffic priority language, called KYKLOFORTA, used by autonomous robots for collision-free navigation in a dynamic unknown or known navigation space. In a previous work by X. Grossmman (1988), a set of traffic control rules was developed for the navigation of the robots on the lines of a two-dimensional (2-D) grid and a control center coordinated and synchronized their movements. In this work, the robots are considered autonomous: they are moving anywhere and in any direction inside the free space, and there is no need of a central control to coordinate and synchronize them. The requirements for each robot are i) visual perception, ii) range sensors, and iii) the ability of each robot to detect other moving objects in the same free navigation space, define the other objects perceived size, their velocity and their directions. Based on these assumptions, a traffic priority language is needed for each robot, making it able to decide during the navigation and avoid possible collision with other moving objects. The traffic priority language proposed here is based on a set of primitive traffic priority alphabet and rules which compose pattern of corridors for the application of the traffic priority rules.

  13. Contact discontinuities in a cold collision-free two-beam plasma

    Science.gov (United States)

    Kirkland, K. B.; Sonnerup, B. U. O.

    1982-01-01

    The structure of contact discontinuities in a collision-free plasma is examined using a model of a plasma which consists of two oppositely directed cold ion beams and a background of cold massless electrons such that exact charge neutrality is maintained and that the electric field is zero. The basic equations describing self-consistent equilibria are obtained for the more general situation where a net flow across the layer takes place and where the magnetic field has two nonzero tangential components but where the electric field remains zero. These equations are then specialized to the case of no net plasma flow where one of the tangential components is zero, and four different classes of sheets are obtained, all having thickness the order of the ion inertial length. The first class is for layers separating two identical plasma and magnetic field regions, the second is for an infinite array of parallel layers producing an undulated magnetic field, the third is for layers containing trapped ions in closed orbits which separate two vacuum regions with uniform identical magnetic fields, and the fourth is for layers which reflect a single plasma beam, leaving a vacuum with a reversed and compressed tangential field on the other side.

  14. Optic flow-based collision-free strategies: From insects to robots.

    Science.gov (United States)

    Serres, Julien R; Ruffier, Franck

    2017-09-01

    Flying insects are able to fly smartly in an unpredictable environment. It has been found that flying insects have smart neurons inside their tiny brains that are sensitive to visual motion also called optic flow. Consequently, flying insects rely mainly on visual motion during their flight maneuvers such as: takeoff or landing, terrain following, tunnel crossing, lateral and frontal obstacle avoidance, and adjusting flight speed in a cluttered environment. Optic flow can be defined as the vector field of the apparent motion of objects, surfaces, and edges in a visual scene generated by the relative motion between an observer (an eye or a camera) and the scene. Translational optic flow is particularly interesting for short-range navigation because it depends on the ratio between (i) the relative linear speed of the visual scene with respect to the observer and (ii) the distance of the observer from obstacles in the surrounding environment without any direct measurement of either speed or distance. In flying insects, roll stabilization reflex and yaw saccades attenuate any rotation at the eye level in roll and yaw respectively (i.e. to cancel any rotational optic flow) in order to ensure pure translational optic flow between two successive saccades. Our survey focuses on feedback-loops which use the translational optic flow that insects employ for collision-free navigation. Optic flow is likely, over the next decade to be one of the most important visual cues that can explain flying insects' behaviors for short-range navigation maneuvers in complex tunnels. Conversely, the biorobotic approach can therefore help to develop innovative flight control systems for flying robots with the aim of mimicking flying insects' abilities and better understanding their flight. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.

  15. Contact discontinuities in a cold collision-free two-beam plasma

    International Nuclear Information System (INIS)

    Kirkland, K.B.; Sonnerup, B.U.O.

    1982-01-01

    A contact discontinuity in a collision-free magnetized plasma is a thin layer, possessing a nontrivial magnetic structure, across which no net plasma flow takes place (#betta#/sub n/ = 0) even though the magnetic field has a nonvanishing component (B/sub n/not =0) normal to it. This paper examines the structure of such discontinuities in a simple plasma model consisting of two oppositely directed cold ion beams and a background of cold massless electrons such that exact charge neutrality is maintained so that the electric field Eequivalent0. The basic equations describing self-consistent equilibria are developed for the more general situation where a net flow across the layer takes place (#betta#/sub n/ = 0) and where the magnetic field has two nonzero tangential components B/sub y/ and B/sub z/ but where E remains zero. These equations are then specialized to the case eta/sub n/equivalent0, B/sub z/equivalent0, and four different classes of sheets are obtained, all having thickness of the order of the ion inertial length: (1) layers separating two identical plasma and magnetic field regions. (2) an infinite array of parallel layers producing an undulated magnetic field, (3) layers containing trapped ions in closed orbits which separate two vacuum regions with uniform identical magnetic fields, and (4) layers which reflect a single plasma beam, leaving a vacuum with a revesed and compressed tangential field on the other side. Solutions for which #betta#/sub n/ = 0 but B/sub z/not =0 may also exist but have not been analyzed; rotational discontinuities are shown not to be possible in this model

  16. Option-implied term structures

    OpenAIRE

    Vogt, Erik

    2014-01-01

    The illiquidity of long-maturity options has made it difficult to study the term structures of option spanning portfolios. This paper proposes a new estimation and inference framework for these option-implied term structures that addresses long-maturity illiquidity. By building a sieve estimator around the risk-neutral valuation equation, the framework theoretically justifies (fat-tailed) extrapolations beyond truncated strikes and between observed maturities while remaining nonparametric. Ne...

  17. IMPLIED AUTHOR IN PHILOSOPHICAL NOVELS

    Directory of Open Access Journals (Sweden)

    Olga Senkāne

    2014-10-01

    Full Text Available The present article falls within a number of papers about research on specification of philosophical novels. The aim of this article is to analyze author’s function as a narrative category in classical philosophical novels (Franz Kafka "The Trial" (1925, "The Castle" (1926, Jean-Paul Sartre "Nausea" (1938, Hermann Hesse "The Glass Bead Game" (1943, Albert Camus "The Plague" (1947 and a novel of Latvian prose writer Ilze Šķipsna "Neapsolītās zemes" ["Un-Promised Lands"] (1970. The analysis is based on theoretical ideas of structural narratologists Gerard Genette, William Labov, Seymuor Chatman, Wolf Schmid, as well as philosophers Edmund Husserl, Jean-Paul Sartre, Paul Ricouer and semioticians Yuri Lotman (Юрий Лотман and Umberto Eco. The real author can ”enter” the text only indirectly—as an image, with the help of the storyteller, and the way how this ”entry” happens is determined by the narration of the real author or narrative (communication skills of the author. Thus, the author and implied author are functionally different concepts: author as a real person develops the concept idea, his intention is to define the concept under his original vision; narrator, in its turn, communicates with the reader, representing the concept, and his aim is to select appropriate means of communication with regard to reader’s perceptual abilities.

  18. 32 CFR 634.8 - Implied consent.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 4 2010-07-01 2010-07-01 true Implied consent. 634.8 Section 634.8 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY (CONTINUED) LAW ENFORCEMENT AND CRIMINAL INVESTIGATIONS MOTOR VEHICLE TRAFFIC SUPERVISION Driving Privileges § 634.8 Implied consent. (a) Implied consent to blood, breath, or urine tests....

  19. Forecasting with Option-Implied Information

    DEFF Research Database (Denmark)

    Christoffersen, Peter; Jacobs, Kris; Chang, Bo Young

    2013-01-01

    This chapter surveys the methods available for extracting information from option prices that can be used in forecasting. We consider option-implied volatilities, skewness, kurtosis, and densities. More generally, we discuss how any forecasting object that is a twice differentiable function...... of the future realization of the underlying risky asset price can utilize option-implied information in a well-defined manner. Going beyond the univariate option-implied density, we also consider results on option-implied covariance, correlation and beta forecasting, as well as the use of option......-implied information in cross-sectional forecasting of equity returns. We discuss how option-implied information can be adjusted for risk premia to remove biases in forecasting regressions....

  20. Implied terms in English and Romanian law

    OpenAIRE

    Stefan Dinu

    2015-01-01

    This study analyses the matter of implied terms from the point of view of both English and Romanian law. First, the introductory section provides a brief overview of implied terms, by defining this class of contractual clauses and by providing their general features. Second, the English law position is analysed, where it is generally recognised that a term may be implied in one of three manners, which are described in turn. An emp hasis is made on the Privy Council’s decision in Attorney G...

  1. Option-implied measures of equity risk

    DEFF Research Database (Denmark)

    Chang, Bo-Young; Christoffersen, Peter; Vainberg, Gregory

    2012-01-01

    Equity risk measured by beta is of great interest to both academics and practitioners. Existing estimates of beta use historical returns. Many studies have found option-implied volatility to be a strong predictor of future realized volatility. We find that option-implied volatility and skewness...... are also good predictors of future realized beta. Motivated by this finding, we establish a set of assumptions needed to construct a beta estimate from option-implied return moments using equity and index options. This beta can be computed using only option data on a single day. It is therefore potentially...

  2. Implied terms in English and Romanian law

    Directory of Open Access Journals (Sweden)

    Stefan Dinu

    2015-12-01

    Full Text Available This study analyses the matter of implied terms from the point of view of both English and Romanian law. First, the introductory section provides a brief overview of implied terms, by defining this class of contractual clauses and by providing their general features. Second, the English law position is analysed, where it is generally recognised that a term may be implied in one of three manners, which are described in turn. An emp hasis is made on the Privy Council’s decision in Attorney General of Belize v Belize Telecom Ltd and its impact. Third, the Romanian law position is described, the starting point of the discussion being represented by the provisions of Article 1272 of the 2009 Civil Code. Fourth, the study ends by mentioning some points of comparison between the two legal systems in what concerns the approach towards implied terms.

  3. Implied Volatility Surface: Construction Methodologies and Characteristics

    OpenAIRE

    Cristian Homescu

    2011-01-01

    The implied volatility surface (IVS) is a fundamental building block in computational finance. We provide a survey of methodologies for constructing such surfaces. We also discuss various topics which can influence the successful construction of IVS in practice: arbitrage-free conditions in both strike and time, how to perform extrapolation outside the core region, choice of calibrating functional and selection of numerical optimization algorithms, volatility surface dynamics and asymptotics.

  4. Asset allocation using option-implied moments

    Science.gov (United States)

    Bahaludin, H.; Abdullah, M. H.; Tolos, S. M.

    2017-09-01

    This study uses an option-implied distribution as the input in asset allocation. The computation of risk-neutral densities (RND) are based on the Dow Jones Industrial Average (DJIA) index option and its constituents. Since the RNDs estimation does not incorporate risk premium, the conversion of RND into risk-world density (RWD) is required. The RWD is obtained through parametric calibration using the beta distributions. The mean, volatility, and covariance are then calculated to construct the portfolio. The performance of the portfolio is evaluated by using portfolio volatility and Sharpe ratio.

  5. XBRL How It Implies The Audit Process

    Directory of Open Access Journals (Sweden)

    Sepky Mardian

    2015-08-01

    Full Text Available This article aimed to know what is XBRL how it works and it implies to audit process. XBRL as a new tool was expected to produce a timelines reliable and credible financial reporting. With its real-time and interactive data XBRL will help the investor and other stakeholder in receiving storing analyzing the information quickly. While in audit profession XBRL will speed up the audit process save the audit cost and increase the revenue. However in fact XBRL will make it happen if it was implemented and integrated to an information system owned by datainformation provider.

  6. Measurement contextuality is implied by macroscopic realism

    International Nuclear Information System (INIS)

    Chen Zeqian; Montina, A.

    2011-01-01

    Ontological theories of quantum mechanics provide a realistic description of single systems by means of well-defined quantities conditioning the measurement outcomes. In order to be complete, they should also fulfill the minimal condition of macroscopic realism. Under the assumption of outcome determinism and for Hilbert space dimension greater than 2, they were all proved to be contextual for projective measurements. In recent years a generalized concept of noncontextuality was introduced that applies also to the case of outcome indeterminism and unsharp measurements. It was pointed out that the Beltrametti-Bugajski model is an example of measurement noncontextual indeterminist theory. Here we provide a simple proof that this model is the only one with such a feature for projective measurements and Hilbert space dimension greater than 2. In other words, there is no extension of quantum theory providing more accurate predictions of outcomes and simultaneously preserving the minimal labeling of events through projective operators. As a corollary, noncontextuality for projective measurements implies noncontextuality for unsharp measurements. By noting that the condition of macroscopic realism requires an extension of quantum theory, unless a breaking of unitarity is invoked, we arrive at the conclusion that the only way to solve the measurement problem in the framework of an ontological theory is by relaxing the hypothesis of measurement noncontextuality in its generalized sense.

  7. Clifford Algebra Implying Three Fermion Generations Revisited

    International Nuclear Information System (INIS)

    Krolikowski, W.

    2002-01-01

    The author's idea of algebraic compositeness of fundamental particles, allowing to understand the existence in Nature of three fermion generations, is revisited. It is based on two postulates. Primo, for all fundamental particles of matter the Dirac square-root procedure √p 2 → Γ (N) ·p works, leading to a sequence N=1, 2, 3, ... of Dirac-type equations, where four Dirac-type matrices Γ (N) μ are embedded into a Clifford algebra via a Jacobi definition introducing four ''centre-of-mass'' and (N - 1) x four ''relative'' Dirac-type matrices. These define one ''centre-of-mass'' and N - 1 ''relative'' Dirac bispinor indices. Secundo, the ''centre-of-mass'' Dirac bispinor index is coupled to the Standard Model gauge fields, while N - 1 ''relative'' Dirac bispinor indices are all free indistinguishable physical objects obeying Fermi statistics along with the Pauli principle which requires the full antisymmetry with respect to ''relative'' Dirac indices. This allows only for three Dirac-type equations with N = 1, 3, 5 in the case of N odd, and two with N = 2, 4 in the case of N even. The first of these results implies unavoidably the existence of three and only three generations of fundamental fermions, namely leptons and quarks, as labelled by the Standard Model signature. At the end, a comment is added on the possible shape of Dirac 3 x 3 mass matrices for four sorts of spin-1/2 fundamental fermions appearing in three generations. For charged leptons a prediction is m τ = 1776.80 MeV, when the input of experimental m e and m μ is used. (author)

  8. Clifford Algebra Implying Three Fermion Generations Revisited

    Science.gov (United States)

    Krolikowski, Wojciech

    2002-09-01

    The author's idea of algebraic compositeness of fundamental particles, allowing to understand the existence in Nature of three fermion generations, is revisited. It is based on two postulates. Primo, for all fundamental particles of matter the Dirac square-root procedure √ {p2} → {Γ }(N)p works, leading to a sequence N = 1,2,3, ... of Dirac-type equations, where four Dirac-type matrices {Γ }(N)μ are embedded into a Clifford algebra via a Jacobi definition introducing four ``centre-of-mass'' and (N-1)× four ``relative'' Dirac-type matrices. These define one ``centre-of-mass'' and (N-1) ``relative'' Dirac bispinor indices. Secundo, the ``centre-of-mass'' Dirac bispinor index is coupled to the Standard Model gauge fields, while (N-1) ``relative'' Dirac bispinor indices are all free indistinguishable physical objects obeying Fermi statistics along with the Pauli principle which requires the full antisymmetry with respect to ``relative'' Dirac indices. This allows only for three Dirac-type equations with N = 1,3,5 in the case of N odd, and two with N = 2,4 in the case of N even. The first of these results implies unavoidably the existence of three and only three generations of fundamental fermions, namely leptons and quarks, as labelled by the Standard Model signature. At the end, a comment is added on the possible shape of Dirac 3x3 mass matrices for four sorts of spin-1/2 fundamental fermions appearing in three generations. For charged leptons a prediction is mτ = 1776.80 MeV, when the input of experimental me and mμ is used.

  9. Entropy-based implied volatility and its information content

    NARCIS (Netherlands)

    X. Xiao (Xiao); C. Zhou (Chen)

    2016-01-01

    markdownabstractThis paper investigates the maximum entropy approach on estimating implied volatility. The entropy approach also allows to measure option implied skewness and kurtosis nonparametrically, and to construct confidence intervals. Simulations show that the en- tropy approach outperforms

  10. Money market rates and implied CCAPM rates: some international evidence

    OpenAIRE

    Yamin Ahmad

    2004-01-01

    New Neoclassical Synthesis models equate the instrument of monetary policy to the implied CCAPM rate arising from an Euler equation. This paper identifies monetary policy shocks within six of the G7 countries and examines the movement of money market and implied CCAPM rates. The key result is that an increase in the nominal interest rate leads to a fall in the implied CCAPM rate. Incorporating habit still yields the same result. The findings suggest that the movement of these two rates implie...

  11. Implied Terms: The Foundation in Good Faith and Fair Dealing

    OpenAIRE

    2014-01-01

    With the aim of clarifying English law of implied terms in contracts and explaining their basis in the idea of good faith in performance, it is argued first that two, but no more, types of implied terms can be distinguished (terms implied in fact and terms implied by law), though it is explained why these types are frequently confused. Second, the technique of implication of terms is distinguished in most instances from the task of interpretation of contracts. Third, it is a...

  12. The Forecast Performance of Competing Implied Volatility Measures

    DEFF Research Database (Denmark)

    Tsiaras, Leonidas

    This study examines the information content of alternative implied volatility measures for the 30 components of the Dow Jones Industrial Average Index from 1996 until 2007. Along with the popular Black-Scholes and "model-free" implied volatility expectations, the recently proposed corridor implie......, volatility definitions, loss functions and forecast evaluation settings....

  13. Introduction to the theory and application of a unified Bohm criterion for arbitrary-ion-temperature collision-free plasmas with finite Debye lengths

    Science.gov (United States)

    Kos, L.; Jelić, N.; Kuhn, S.; Tskhakaya, D. D.

    2018-04-01

    Tonks-Langmuir collision-free, plane-parallel discharge model [Phys. Rev. 34, 876 (1929)], however, with the ion-source temperature extended here from the original (zero) value to arbitrary high ones. In addition, it turns out, that the charge-density derivative (in the potential "space") with respect to the potential exhibits two characteristic points, i.e., potentials, namely the points of inflection and maximum of that derivative (in the potential space), which stay "fixed" at their respective potentials independent of the Debye length until it is kept fairly small. Plasma quasi-neutrality appears well satisfied up to the first characteristic point/potential, so we identify that one as the plasma edge (PE). Adopting the convention that the sheath is a region characterized by considerable electrostatic pressure (energy density), we identify the second characteristic point/potential as the sheath edge (SE). Between these points, the charge density increases from zero to a finite value. Thus, the interval between the PE and SE, with the "fixed" width (in the potential "space") of about one third of the electron temperature, will be named the plasma-sheath transition (PST). Outside the PST, the electrostatic-pressure term and its derivatives turn out to be nearly identical with each other, independent of the particular values of the ion temperature and Debye length. In contrast, an increase in Debye lengths from zero to finite values causes the location of the sonic point/potential (laying inside the PST) to shift from the PE (for vanishing Debye length) towards the SE, while at the same time, the absolute value of the corresponding ion-sound velocity slightly decreases. These shifts turn out to be manageable with employing the mathematical concept of the plasma-to-sheath transition (different from, but related to our natural PST concept), resulting in approximate, but sufficiently reliable semi-analytic expressions, which are functions of the ion temperature and Debye

  14. Implied liquidity : towards stochastic liquidity modeling and liquidity trading

    NARCIS (Netherlands)

    Corcuera, J.M.; Guillaume, F.M.Y.; Madan, D.B.; Schoutens, W.

    2010-01-01

    In this paper we introduce the concept of implied (il)liquidity of vanilla options. Implied liquidity is based on the fundamental theory of conic finance, in which the one-price model is abandoned and replaced by a two-price model giving bid and ask prices for traded assets. The pricing is done by

  15. Asymptotic formulae for implied volatility in the Heston model

    OpenAIRE

    Forde, Martin; Jacquier, Antoine; Mijatovic, Aleksandar

    2009-01-01

    In this paper we prove an approximate formula expressed in terms of elementary functions for the implied volatility in the Heston model. The formula consists of the constant and first order terms in the large maturity expansion of the implied volatility function. The proof is based on saddlepoint methods and classical properties of holomorphic functions.

  16. Optimal higher-order encoder time-stamping

    NARCIS (Netherlands)

    Merry, R.J.E.; Molengraft, van de M.J.G.; Steinbuch, M.

    2013-01-01

    Optical incremental encoders are used to measure the position of motion control systems. The accuracy of the position measurement is determined and bounded by the number of slits on the encoder. The position measurement is affected by quantization errors and encoder imperfections. In this paper, an

  17. Multifractal analysis of implied volatility in index options

    Science.gov (United States)

    Oh, GabJin

    2014-06-01

    In this paper, we analyze the statistical and the non-linear properties of the log-variations in implied volatility for the CAC40, DAX and S& P500 daily index options. The price of an index option is generally represented by its implied volatility surface, including its smile and skew properties. We utilize a Lévy process model as the underlying asset to deepen our understanding of the intrinsic property of the implied volatility in the index options and estimate the implied volatility surface. We find that the options pricing models with the exponential Lévy model can reproduce the smile or sneer features of the implied volatility that are observed in real options markets. We study the variation in the implied volatility for at-the-money index call and put options, and we find that the distribution function follows a power-law distribution with an exponent of 3.5 ≤ γ ≤ 4.5. Especially, the variation in the implied volatility exhibits multifractal spectral characteristics, and the global financial crisis has influenced the complexity of the option markets.

  18. Electrodermal responses to implied versus actual violence on television.

    Science.gov (United States)

    Kalamas, A D; Gruber, M L

    1998-01-01

    The electrodermal response (EDR) of children watching a violent show was measured. Particular attention was paid to the type of violence (actual or implied) that prompted an EDR. In addition, the impact of the auditory component (sounds associated with violence) of the show was evaluated. Implied violent stimuli, such as the villain's face, elicited the strongest EDR. The elements that elicited the weakest responses were the actual violent stimuli, such as stabbing. The background noise and voices of the sound track enhanced the total number of EDRs. The results suggest that implied violence may elicit more fear (as measured by EDRs) than actual violence does and that sounds alone contribute significantly to the emotional response to television violence. One should not, therefore, categorically assume that a show with mostly actual violence evokes less fear than one with mostly implied violence.

  19. Correlation Structures of Correlated Binomial Models and Implied Default Distribution

    OpenAIRE

    S. Mori; K. Kitsukawa; M. Hisakado

    2006-01-01

    We show how to analyze and interpret the correlation structures, the conditional expectation values and correlation coefficients of exchangeable Bernoulli random variables. We study implied default distributions for the iTraxx-CJ tranches and some popular probabilistic models, including the Gaussian copula model, Beta binomial distribution model and long-range Ising model. We interpret the differences in their profiles in terms of the correlation structures. The implied default distribution h...

  20. Predicting Agency Rating Migrations with Spread Implied Ratings

    OpenAIRE

    Jianming Kou; Dr Simone Varotto

    2005-01-01

    Investors traditionally rely on credit ratings to price debt instruments. However, rating agencies are known to be prudent in their approach to rating revisions, which results in delayed ratings adjustments to mutating credit conditions. For a large set of eurobonds we derive credit spread implied ratings and compare them with the ratings issued by rating agencies. Our results indicate that spread implied ratings often anticipate future movement of agency ratings and hence could help track cr...

  1. Uniform Bounds for Black--Scholes Implied Volatility

    OpenAIRE

    Tehranchi, Michael Rummine

    2016-01-01

    In this note, Black--Scholes implied volatility is expressed in terms of various optimization problems. From these representations, upper and lower bounds are derived which hold uniformly across moneyness and call price. Various symmetries of the Black--Scholes formula are exploited to derive new bounds from old. These bounds are used to reprove asymptotic formulas for implied volatility at extreme strikes and/or maturities. the Society for Industrial and Applied Mathematics 10.1137/14095248X

  2. Uniform bounds for Black--Scholes implied volatility

    OpenAIRE

    Tehranchi, Michael R.

    2015-01-01

    In this note, Black--Scholes implied volatility is expressed in terms of various optimisation problems. From these representations, upper and lower bounds are derived which hold uniformly across moneyness and call price. Various symmetries of the Black--Scholes formula are exploited to derive new bounds from old. These bounds are used to reprove asymptotic formulae for implied volatility at extreme strikes and/or maturities.

  3. Long memory and the relation between implied and realized volatility

    OpenAIRE

    Federico Bandi; Benoit Perron

    2003-01-01

    We argue that the conventional predictive regression between implied volatility (regressor) and realized volatility over the remaining life of the option (regressand) is likely to be a fractional cointegrating relation. Since cointegration is associated with long-run comovements, this finding modifies the usual interpretation of such regression as a study towards assessing option market efficiency (given a certain option pricing model) and/or short-term unbiasedness of implied volatility as a...

  4. Long memory persistence in the factor of Implied volatility dynamics

    OpenAIRE

    Härdle, Wolfgang Karl; Mungo, Julius

    2007-01-01

    The volatility implied by observed market prices as a function of the strike and time to maturity form an Implied Volatility Surface (IV S). Practical applications require reducing the dimension and characterize its dynamics through a small number of factors. Such dimension reduction is summarized by a Dynamic Semiparametric Factor Model (DSFM) that characterizes the IV S itself and their movements across time by a multivariate time series of factor loadings. This paper focuses on investigati...

  5. US Implied Volatility as A predictor of International Returns

    Directory of Open Access Journals (Sweden)

    Mehmet F. Dicle

    2017-12-01

    Full Text Available This study provides evidence of the US implied volatility’s e ect on international equitymarkets’ returns. This evidence has two main implications: i investors may find that foreign equityreturns adjusting to US implied volatility may not provide true diversification benefits, and ii foreignequity returns may be predicted using US implied volatility. Our sample includes US volatility index(VIX and major equity indexes in twenty countries for the period between January, 2000 throughJuly, 2017. VIX leads eighteen of the international markets and Granger causes seventeen of themarkets after controlling for the S&P-500 index returns and the 2007/2008 US financial crisis. USinvestors looking to diversify US risk may find that international equities may not provide intendeddiversification benefits. Our evidence provides support for predictability of international equity returnsbased on US volatility.

  6. Correlation Structures of Correlated Binomial Models and Implied Default Distribution

    Science.gov (United States)

    Mori, Shintaro; Kitsukawa, Kenji; Hisakado, Masato

    2008-11-01

    We show how to analyze and interpret the correlation structures, the conditional expectation values and correlation coefficients of exchangeable Bernoulli random variables. We study implied default distributions for the iTraxx-CJ tranches and some popular probabilistic models, including the Gaussian copula model, Beta binomial distribution model and long-range Ising model. We interpret the differences in their profiles in terms of the correlation structures. The implied default distribution has singular correlation structures, reflecting the credit market implications. We point out two possible origins of the singular behavior.

  7. Tachyons imply the existence of a privileged frame

    Energy Technology Data Exchange (ETDEWEB)

    Sjoedin, T.; Heylighen, F.

    1985-12-16

    It is shown that the existence of faster-than-light signals (tachyons) would imply the existence (and detectability) of a privileged inertial frame and that one can avoid all problems with reversed-time order only by using absolute synchronization instead of the standard one. The connection between these results and the EPR-paradox is discussed.

  8. Comprehending Implied Meaning in English as a Foreign Language

    Science.gov (United States)

    Taguchi, Naoko

    2005-01-01

    This study investigated whether second language (L2) proficiency affects pragmatic comprehension, namely the ability to comprehend implied meaning in spoken dialogues, in terms of accuracy and speed of comprehension. Participants included 46 native English speakers at a U.S. university and 160 Japanese students of English in a college in Japan who…

  9. Estimating implied rates of discount in healthcare decision-making.

    Science.gov (United States)

    West, R R; McNabb, R; Thompson, A G H; Sheldon, T A; Grimley Evans, J

    2003-01-01

    To consider whether implied rates of discounting from the perspectives of individual and society differ, and whether implied rates of discounting in health differ from those implied in choices involving finance or "goods". The study comprised first a review of economics, health economics and social science literature and then an empirical estimate of implied rates of discounting in four fields: personal financial, personal health, public financial and public health, in representative samples of the public and of healthcare professionals. Samples were drawn in the former county and health authority district of South Glamorgan, Wales. The public sample was a representative random sample of men and women, aged over 18 years and drawn from electoral registers. The health professional sample was drawn at random with the cooperation of professional leads to include doctors, nurses, professions allied to medicine, public health, planners and administrators. The literature review revealed few empirical studies in representative samples of the population, few direct comparisons of public with private decision-making and few direct comparisons of health with financial discounting. Implied rates of discounting varied widely and studies suggested that discount rates are higher the smaller the value of the outcome and the shorter the period considered. The relationship between implied discount rates and personal attributes was mixed, possibly reflecting the limited nature of the samples. Although there were few direct comparisons, some studies found that individuals apply different rates of discount to social compared with private comparisons and health compared with financial. The present study also found a wide range of implied discount rates, with little systematic effect of age, gender, educational level or long-term illness. There was evidence, in both samples, that people chose a lower rate of discount in comparisons made on behalf of society than in comparisons made for

  10. Intuitive understanding of nonlocality as implied by quantum theory

    International Nuclear Information System (INIS)

    Bohm, D.G.; Hiley, B.J.

    1975-01-01

    The fact is brought out that the essential new quality implied by the quantum theory is nonlocality; i.e., that a system cannot be analyzed into parts whose basic properties do not depend on the state of the whole system. This is done in terms of the causal interpretation of the quantum theory, proposed by one of us (D.B.) in 2952, involving the introduction of the ''quantum potential.'' It is shown that this approach implies a new universal type of description, in which the standard or canonical form is always supersystem-system-subsystem; and this leads to the radically new notion of unbroken wholeness of the entire universe. Finally, some of the implications of extending these notions to the relativity domain, and in so doing, a novel concept of time, in terms of which relativity and quantum theory may eventually be brought together, is indicated

  11. Implied Movement in Static Images Reveals Biological Timing Processing

    Directory of Open Access Journals (Sweden)

    Francisco Carlos Nather

    2015-08-01

    Full Text Available Visual perception is adapted toward a better understanding of our own movements than those of non-conspecifics. The present study determined whether time perception is affected by pictures of different species by considering the evolutionary scale. Static (“S” and implied movement (“M” images of a dog, cheetah, chimpanzee, and man were presented to undergraduate students. S and M images of the same species were presented in random order or one after the other (S-M or M-S for two groups of participants. Movement, Velocity, and Arousal semantic scales were used to characterize some properties of the images. Implied movement affected time perception, in which M images were overestimated. The results are discussed in terms of visual motion perception related to biological timing processing that could be established early in terms of the adaptation of humankind to the environment.

  12. Language comprehenders retain implied shape and orientation of objects.

    Science.gov (United States)

    Pecher, Diane; van Dantzig, Saskia; Zwaan, Rolf A; Zeelenberg, René

    2009-06-01

    According to theories of embodied cognition, language comprehenders simulate sensorimotor experiences to represent the meaning of what they read. Previous studies have shown that picture recognition is better if the object in the picture matches the orientation or shape implied by a preceding sentence. In order to test whether strategic imagery may explain previous findings, language comprehenders first read a list of sentences in which objects were mentioned. Only once the complete list had been read was recognition memory tested with pictures. Recognition performance was better if the orientation or shape of the object matched that implied by the sentence, both immediately after reading the complete list of sentences and after a 45-min delay. These results suggest that previously found match effects were not due to strategic imagery and show that details of sensorimotor simulations are retained over longer periods.

  13. Implied Materiality and Material Disclosures of Credit Ratings

    OpenAIRE

    Eccles, Robert G; Youmans, Timothy John

    2015-01-01

    This first of three papers in our series on materiality in credit ratings will examine the materiality of credit ratings from an “implied materiality” and governance disclosure perspective. In the second paper, we will explore the materiality of environmental, social, and governance (ESG) factors in credit ratings’ methodologies and introduce the concept of “layered materiality.” In the third paper, we will evaluate current and potential credit rating agency (CRA) business models based on our...

  14. On return rate implied by behavioural present value

    OpenAIRE

    Piasecki, Krzysztof

    2013-01-01

    The future value of a security is described as a random variable. Distribution of this random variable is the formal image of risk uncertainty. On the other side, any present value is defined as a value equivalent to the given future value. This equivalence relationship is a subjective. Thus follows, that present value is described as a fuzzy number, which is depend on the investor's susceptibility to behavioural factors. All above reasons imply, that return rate is given as a fuzzy probabili...

  15. Wave function collapse implies divergence of average displacement

    OpenAIRE

    Marchewka, A.; Schuss, Z.

    2005-01-01

    We show that propagating a truncated discontinuous wave function by Schr\\"odinger's equation, as asserted by the collapse axiom, gives rise to non-existence of the average displacement of the particle on the line. It also implies that there is no Zeno effect. On the other hand, if the truncation is done so that the reduced wave function is continuous, the average coordinate is finite and there is a Zeno effect. Therefore the collapse axiom of measurement needs to be revised.

  16. TEMPORAL INSENSITIVITY OF PVWTP AND IMPLIED DISCOUNT RATES IN CVM

    OpenAIRE

    Kim, Sooil; Haab, Timothy C.

    2003-01-01

    The sensitivity of WTP is tested in terms of the present value and the implied discount rates are derived by varying the length of benefit and the temporal payment schedules. Results show that holding the length of the project constant, the present value of willingness to pay does not vary significantly across payment schemes (one time payment, versus life of the project, versus perpetuity). Heteroskedasticity of error term over payment schemes fails to be accepted. Holding the payment scheme...

  17. Interpreting the implied meridional oceanic energy transport in AMIP

    International Nuclear Information System (INIS)

    Randall, D.A.; Gleckler, P.J.

    1993-09-01

    The Atmospheric Model Intercomparison Project (AMIP) was outlined in Paper No. CLIM VAR 2.3 (entitled open-quote The validation of ocean surface heat fluxes in AMIP') of these proceedings. Preliminary results of AMIP subproject No. 5 were also summarized. In particular, zonally averaged ocean surface heat fluxes resulting from various AMIP simulations were intercompared, and to the extent possible they were validated with uncertainties in observationally-based estimates of surface heat fluxes. The intercomparison is continued in this paper by examining the Oceanic Meridional Energy Transport (OMET) implied by the net surface heat fluxes of the AMIP simulations. As with the surface heat fluxes of the AMIP simulations. As with the surface heat fluxes, the perspective here will be very cursory. The annual mean implied ocean heat transport can be estimated by integrating the zonally averaged net ocean surface heat flux, N sfc , from one pole to the other. In AGCM simulations (and perhaps reality), the global mean N sfc is typically not in exact balance when averaged over one or more years. Because of this, an important assumption must be made about changes in the distribution of energy in the oceans. Otherwise, the integration will yield a non-zero transport at the endpoint of integration (pole) which is not physically realistic. Here the authors will only look at 10-year means of the AMIP runs, and for simplicity they assume that any long term imbalance in the global averaged N sfc will be sequestered (or released) over the global ocean. Tests have demonstrated that the treatment of how the global average energy imbalance is assumed to be distributed is important, especially when the long term imbalances are in excess of 10 W m -2 . However, this has not had a substantial impact on the qualitative features of the implied heat transport of the AMIP simulations examined thus far

  18. Implied reading direction and prioritization of letter encoding.

    Science.gov (United States)

    Holcombe, Alex O; Nguyen, Elizabeth H L; Goodbourn, Patrick T

    2017-10-01

    Capacity limits hinder processing of multiple stimuli, contributing to poorer performance for identifying two briefly presented letters than for identifying a single letter. Higher accuracy is typically found for identifying the letter on the left, which has been attributed to a right-hemisphere dominance for selective attention. Here, we use rapid serial visual presentation (RSVP) of letters in two locations at once. The letters to be identified are simultaneous and cued by rings. In the first experiment, we manipulated implied reading direction by rotating or mirror-reversing the letters to face to the left rather than to the right. The left-side performance advantage was eliminated. In the second experiment, letters were positioned above and below fixation, oriented such that they appeared to face downward (90° clockwise rotation) or upward (90° counterclockwise rotation). Again consistent with an effect of implied reading direction, performance was better for the top position in the downward condition, but not in the upward condition. In both experiments, mixture modeling of participants' report errors revealed that attentional sampling from the two locations was approximately simultaneous, ruling out the theory that the letter on one side was processed first, followed by a shift of attention to sample the other letter. Thus, the orientation of the letters apparently controls not when the letters are sampled from the scene, but rather the dynamics of a subsequent process, such as tokenization or memory consolidation. Implied reading direction appears to determine the letter prioritized at a high-level processing bottleneck. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  19. Noninvadability implies noncoexistence for a class of cancellative systems

    Czech Academy of Sciences Publication Activity Database

    Swart, Jan M.

    2013-01-01

    Roč. 18, č. 38 (2013), s. 1-12 ISSN 1083-589X R&D Projects: GA ČR GAP201/10/0752 Institutional support: RVO:67985556 Keywords : cancellative system * interface tightness * duality * coexistence * Neuhauser-Pacala model * affine voter model * rebellious voter model * balancing selection * branching * annihilation * parity preservation Subject RIV: BA - General Mathematics Impact factor: 0.627, year: 2013 http://library.utia.cas.cz/separaty/2013/SI/swart-noninvadability implies noncoexistence for a class of cancellative systems.pdf

  20. Likelihood ratio decisions in memory: three implied regularities.

    Science.gov (United States)

    Glanzer, Murray; Hilford, Andrew; Maloney, Laurence T

    2009-06-01

    We analyze four general signal detection models for recognition memory that differ in their distributional assumptions. Our analyses show that a basic assumption of signal detection theory, the likelihood ratio decision axis, implies three regularities in recognition memory: (1) the mirror effect, (2) the variance effect, and (3) the z-ROC length effect. For each model, we present the equations that produce the three regularities and show, in computed examples, how they do so. We then show that the regularities appear in data from a range of recognition studies. The analyses and data in our study support the following generalization: Individuals make efficient recognition decisions on the basis of likelihood ratios.

  1. Faster than light motion does not imply time travel

    International Nuclear Information System (INIS)

    Andréka, Hajnal; Madarász, Judit X; Németi, István; Székely, Gergely; Stannett, Mike

    2014-01-01

    Seeing the many examples in the literature of causality violations based on faster than light (FTL) signals one naturally thinks that FTL motion leads inevitably to the possibility of time travel. We show that this logical inference is invalid by demonstrating a model, based on (3+1)-dimensional Minkowski spacetime, in which FTL motion is permitted (in every direction without any limitation on speed) yet which does not admit time travel. Moreover, the Principle of Relativity is true in this model in the sense that all observers are equivalent. In short, FTL motion does not imply time travel after all. (paper)

  2. Implied Reading in the Unforgettable Stories of Language Learners

    Directory of Open Access Journals (Sweden)

    Feryal ÇUBUKÇU

    2017-09-01

    Full Text Available Iser is literary theoretician and co-founder of the Constance School of Reception Aesthetics, professor Emeritus of English and Comparative Literature at the University of Constance and the University of California, Irvine. When Iser died in 2007 in his eighty-first year, he was one of the most widely known literary theoreticians in the world. His “implied reading” theory claims that texts can themselves also awaken false expectations, alternately bringing about surprise, joy and frustration, which can be the enlargement of experience. The indeterminacy of the text might yield different responses from different readers. To prove that each implied reading is based on the schemata of the readers, this study aims at analysing the stories told by language learners of Turkish who come from 20 countries and whose ages vary between 18-32. The participants are 65 undergraduate and graduate university students, from African, Asian and Balkan countries, who upon watching “Cinderella” were asked to write about the unforgettable folk story or fairy tale. When their stories are item analysed, the results show that the schematas of the learners shape the way they choose and recount the stories. Leraners of Turkish fill in the gaps throughout the story, form a meaningful bond by pulling information from it, participating in a reciprocal relationship, creating and deriving meaning in an extravaganza of interpretation.

  3. Vertebrate Fossils Imply Paleo-elevations of the Tibetan Plateau

    Science.gov (United States)

    Deng, T.; Wang, X.; Li, Q.; Wu, F.; Wang, S.; Hou, S.

    2017-12-01

    The uplift of the Tibetan Plateau remains unclear, and its paleo-elevation reconstructions are crucial to interpret the geodynamic evolution and to understand the climatic changes in Asia. Uplift histories of the Tibetan Plateau based on different proxies differ considerably, and two viewpoints are pointedly opposing on the paleo-elevation estimations of the Tibetan Plateau. One viewpoint is that the Tibetan Plateau did not strongly uplift to reach its modern elevation until the Late Miocene, but another one, mainly based on stable isotopes, argues that the Tibetan Plateau formed early during the Indo-Asian collision and reached its modern elevation in the Paleogene or by the Middle Miocene. In 1839, Hugh Falconer firstly reported some rhinocerotid fossils collected from the Zanda Basin in Tibet, China and indicated that the Himalayas have uplifted by more than 2,000 m since several million years ago. In recent years, the vertebrate fossils discovered from the Tibetan Plateau and its surrounding areas implied a high plateau since the late Early Miocene. During the Oligocene, giant rhinos lived in northwestern China to the north of the Tibetan Plateau, while they were also distributed in the Indo-Pakistan subcontinent to the south of this plateau, which indicates that the elevation of the Tibetan Plateau was not too high to prevent exchanges of large mammals; giant rhinos, the rhinocerotid Aprotodon, and chalicotheres still dispersed north and south of "Tibetan Plateau". A tropical-subtropical lowland fish fauna was also present in the central part of this plateau during the Late Oligocene, in which Eoanabas thibetana was inferred to be closely related to extant climbing perches from South Asia and Sub-Saharan Africa. In contrast, during the Middle Miocene, the shovel-tusked elephant Platybelodon was found from many localities north of the Tibetan Plateau, while its trace was absent in the Siwaliks of the subcontinent, which implies that the Tibetan Plateau had

  4. Time-to-contact estimation modulated by implied friction.

    Science.gov (United States)

    Yamada, Yuki; Sasaki, Kyoshiro; Miura, Kayo

    2014-01-01

    The present study demonstrated that friction cues for target motion affect time-to-contact (TTC) estimation. A circular target moved in a linear path with a constant velocity and was gradually occluded by a static rectangle. The target moved with forward and backward spins or without spin. Observers were asked to respond at the time when the moving target appeared to pass the occluder. The results showed that TTC was significantly longer in the backward spin condition than in the forward and without-spin conditions. Moreover, similar results were obtained when a sound was used to imply friction. Our findings indicate that the observer's experiential knowledge of motion coupled with friction intuitively modulated their TTC estimation.

  5. Short-Term Market Risks Implied by Weekly Options

    DEFF Research Database (Denmark)

    Andersen, Torben Gustav; Fusari, Nicola; Todorov, Viktor

    a direct way to study volatility and jump risks. Unlike longer-dated options, they are largely insensitive to the risk of intertemporal shifts in the economic environment. Adopting a novel semi-nonparametric approach, we uncover variation in the negative jump tail risk which is not spanned by market......We study short-term market risks implied by weekly S&P 500 index options. The introduction of weekly options has dramatically shifted the maturity profile of traded options over the last five years, with a substantial proportion now having expiry within one week. Such short-dated options provide......" by the level of market volatility and elude standard asset pricing models....

  6. Implied motion language can influence visual spatial memory.

    Science.gov (United States)

    Vinson, David W; Engelen, Jan; Zwaan, Rolf A; Matlock, Teenie; Dale, Rick

    2017-07-01

    How do language and vision interact? Specifically, what impact can language have on visual processing, especially related to spatial memory? What are typically considered errors in visual processing, such as remembering the location of an object to be farther along its motion trajectory than it actually is, can be explained as perceptual achievements that are driven by our ability to anticipate future events. In two experiments, we tested whether the prior presentation of motion language influences visual spatial memory in ways that afford greater perceptual prediction. Experiment 1 showed that motion language influenced judgments for the spatial memory of an object beyond the known effects of implied motion present in the image itself. Experiment 2 replicated this finding. Our findings support a theory of perception as prediction.

  7. Limits on rare B decays B implies μ+μ-K± and B implies μ+μ- K*

    International Nuclear Information System (INIS)

    Anway-Wiese, C.

    1995-01-01

    We report on a search for flavor-changing neutral current decays of B mesons into γγK * and γγK± using data obtained in the Collider Detector at Fermilab (CDF) 1992 endash 1993 data taking run. To reduce the amount of background in our data we use precise tracking information from the CDF silicon vertex detector to pinpoint the location of the decay vertex of the B candidate, and accept only events which have a large decay time.We compare this data to a B meson signal obtained in a similar fashion, but where the muon pairs originate from ψ decays, and calculate the relative branching ratios. In the absence of any indication of flavor-changing neutral current decays we set an upper limits of BR(B implies μμK ± ) much-gt 3.5x10 -5 , and BR(B implies μμK * )much-gt 5.1x10 -5 at 90% confidence level, which are consistent with Standard Model expectations but leave little room for non-standard physics. copyright 1995 American Institute of Physics

  8. Stringent Mitigation Policy Implied By Temperature Impacts on Economic Growth

    Science.gov (United States)

    Moore, F.; Turner, D.

    2014-12-01

    Integrated assessment models (IAMs) compare the costs of greenhouse gas mitigation with damages from climate change in order to evaluate the social welfare implications of climate policy proposals and inform optimal emissions reduction trajectories. However, these models have been criticized for lacking a strong empirical basis for their damage functions, which do little to alter assumptions of sustained GDP growth, even under extreme temperature scenarios. We implement empirical estimates of temperature effects on GDP growth-rates in the Dynamic Integrated Climate and Economy (DICE) model via two pathways, total factor productivity (TFP) growth and capital depreciation. Even under optimistic adaptation assumptions, this damage specification implies that optimal climate policy involves the elimination of emissions in the near future, the stabilization of global temperature change below 2°C, and a social cost of carbon (SCC) an order of magnitude larger than previous estimates. A sensitivity analysis shows that the magnitude of growth effects, the rate of adaptation, and the dynamic interaction between damages from warming and GDP are three critical uncertainties and an important focus for future research.

  9. Collective memory in primate conflict implied by temporal scaling collapse.

    Science.gov (United States)

    Lee, Edward D; Daniels, Bryan C; Krakauer, David C; Flack, Jessica C

    2017-09-01

    In biological systems, prolonged conflict is costly, whereas contained conflict permits strategic innovation and refinement. Causes of variation in conflict size and duration are not well understood. We use a well-studied primate society model system to study how conflicts grow. We find conflict duration is a 'first to fight' growth process that scales superlinearly, with the number of possible pairwise interactions. This is in contrast with a 'first to fail' process that characterizes peaceful durations. Rescaling conflict distributions reveals a universal curve, showing that the typical time scale of correlated interactions exceeds nearly all individual fights. This temporal correlation implies collective memory across pairwise interactions beyond those assumed in standard models of contagion growth or iterated evolutionary games. By accounting for memory, we make quantitative predictions for interventions that mitigate or enhance the spread of conflict. Managing conflict involves balancing the efficient use of limited resources with an intervention strategy that allows for conflict while keeping it contained and controlled. © 2017 The Author(s).

  10. Analysis of Federal Subsidies: Implied Price of Carbon

    Energy Technology Data Exchange (ETDEWEB)

    D. Craig Cooper; Thomas Foulke

    2010-10-01

    For informed climate change policy, it is important for decision makers to be able to assess how the costs and benefits of federal energy subsidies are distributed and to be able to have some measure to compare them. One way to do this is to evaluate the implied price of carbon (IPC) for a federal subsidy, or set of subsidies; where the IPC is the cost of the subsidy to the U.S. Treasury divided by the emissions reductions it generated. Subsidies with lower IPC are more cost effective at reducing greenhouse gas emissions, while subsidies with a negative IPC act to increase emissions. While simple in concept, the IPC is difficult to calculate in practice. Calculation of the IPC requires knowledge of (i) the amount of energy associated with the subsidy, (ii) the amount and type of energy that would have been produced in the absence of the subsidy, and (iii) the greenhouse gas emissions associated with both the subsidized energy and the potential replacement energy. These pieces of information are not consistently available for federal subsidies, and there is considerable uncertainty in cases where the information is available. Thus, exact values for the IPC based upon fully consistent standards cannot be calculated with available data. However, it is possible to estimate a range of potential values sufficient for initial comparisons. This study has employed a range of methods to generate “first order” estimates for the IPC of a range of federal subsidies using static methods that do not account for the dynamics of supply and demand. The study demonstrates that, while the IPC value depends upon how the inquiry is framed and the IPC cannot be calculated in a “one size fits all” manner, IPC calculations can provide a valuable perspective for climate policy analysis. IPC values are most useful when calculated within the perspective of a case study, with the method and parameters of the calculation determined by the case. The IPC of different policy measures can

  11. Implied and realized volatility in the cross-section of equity options

    DEFF Research Database (Denmark)

    Ammann, Manuel; Skovmand, David; Verhofen, Michael

    2009-01-01

    Using a complete sample of US equity options, we analyze patterns of implied volatility in the cross-section of equity options with respect to stock characteristics. We find that high-beta stocks, small stocks, stocks with a low-market-to-book ratio, and non-momentum stocks trade at higher implied...

  12. 76 FR 55904 - Michael J. Donahue; Notice of Termination of Exemption By Implied Surrender and Soliciting...

    Science.gov (United States)

    2011-09-09

    .... Donahue; Notice of Termination of Exemption By Implied Surrender and Soliciting Comments, Protests, and... Commission: a. Type of Proceeding: Termination of exemption by implied surrender. b. Project No.: 6649-008. c... Commission reserves the right to revoke an exemption if any term or condition of the exemption is violated...

  13. 76 FR 58264 - Michael J. Donahue; Notice of Termination of Exemption by Implied Surrender and Soliciting...

    Science.gov (United States)

    2011-09-20

    .... Donahue; Notice of Termination of Exemption by Implied Surrender and Soliciting Comments, Protests, and... Commission: a. Type of Proceeding: Termination of exemption by implied surrender. b. Project No.: 6649-008. c... Commission reserves the right to revoke an exemption if any term or condition of the exemption is violated...

  14. 77 FR 2057 - Aquamac Corporation; Notice of Termination of License by Implied Surrender and Soliciting...

    Science.gov (United States)

    2012-01-13

    ... Corporation; Notice of Termination of License by Implied Surrender and Soliciting Comments and Motions To.... Type of Proceeding: Termination of License by Implied Surrender. b. Project No.: 2927-006. c. Date... authorized, the licensee is in violation of the terms and conditions of the license. l. This notice is...

  15. 77 FR 73653 - Milburnie Hydro Inc.; Notice of Termination of Exemption by Implied Surrender and Soliciting...

    Science.gov (United States)

    2012-12-11

    ... Inc.; Notice of Termination of Exemption by Implied Surrender and Soliciting Comments, Protests, and... Commission: a. Type of Proceeding: Termination of exemption by implied surrender. b. Project No.: 7910-006. c... Commission reserves the right to revoke an exemption if any term or condition of the exemption is violated...

  16. 76 FR 55903 - Missisquoi River Technologies; Notice of Termination of Exemption By Implied Surrender and...

    Science.gov (United States)

    2011-09-09

    ... Technologies; Notice of Termination of Exemption By Implied Surrender and Soliciting Comments, Protests, and... Commission: a. Type of Proceeding: Termination of exemption by implied surrender. b. Project No.: 10172-038..., among other things, that the Commission reserves the right to revoke an exemption if any term or...

  17. 76 FR 7840 - American Hydro Power Company; Notice of Termination of Exemption by Implied Surrender and...

    Science.gov (United States)

    2011-02-11

    ... Power Company; Notice of Termination of Exemption by Implied Surrender and Soliciting Comments, Protests... the Commission: a. Type of Proceeding: Termination of exemption by implied surrender. b. Project No... if any term or condition of the exemption is violated. The project has not operated since 2004, and...

  18. Advising Students or Practicing Law: The Formation of Implied Attorney-Client Relationships with Students

    Science.gov (United States)

    Sheridan, Patricia M.

    2014-01-01

    An attorney-client relationship is traditionally created when both parties formally enter into an express agreement regarding the terms of representation and the payment of fees. There are certain circumstances, however, where the attorney-client relationship can be implied from the parties' conduct. An implied attorney-client relationship may…

  19. Fractional Black–Scholes option pricing, volatility calibration and implied Hurst exponents in South African context

    Directory of Open Access Journals (Sweden)

    Emlyn Flint

    2017-03-01

    Full Text Available Background: Contingent claims on underlying assets are typically priced under a framework that assumes, inter alia, that the log returns of the underlying asset are normally distributed. However, many researchers have shown that this assumption is violated in practice. Such violations include the statistical properties of heavy tails, volatility clustering, leptokurtosis and long memory. This paper considers the pricing of contingent claims when the underlying is assumed to display long memory, an issue that has heretofore not received much attention. Aim: We address several theoretical and practical issues in option pricing and implied volatility calibration in a fractional Black–Scholes market. We introduce a novel eight-parameter fractional Black–Scholes-inspired (FBSI model for the implied volatility surface, and consider in depth the issue of calibration. One of the main benefits of such a model is that it allows one to decompose implied volatility into an independent long-memory component – captured by an implied Hurst exponent – and a conditional implied volatility component. Such a decomposition has useful applications in the areas of derivatives trading, risk management, delta hedging and dynamic asset allocation. Setting: The proposed FBSI volatility model is calibrated to South African equity index options data as well as South African Rand/American Dollar currency options data. However, given the focus on the theoretical development of the model, the results in this paper are applicable across all financial markets. Methods: The FBSI model essentially combines a deterministic function form of the 1-year implied volatility skew with a separate deterministic function for the implied Hurst exponent, thus allowing one to model both observed implied volatility surfaces as well as decompose them into independent volatility and long-memory components respectively. Calibration of the model makes use of a quasi-explicit weighted

  20. The implied volatility of U.S. interest rates: evidence from callable U. S. Treasuries

    OpenAIRE

    Robert R. Bliss; Ehud I. Ronn

    1995-01-01

    The prices for callable U.S. Treasury securities provide the sole source of evidence concerning the implied volatility of interest rates over the extended 1926-1994 period. This paper uses the prices of callable as well as non-callable Treasury instruments to estimate implied interest rate volatilities for the past sixty years, and, for the more recent 1989-1994 period, the cross-sectional term structures of implied interest rate volatility. We utilize these estimates to perform cross-section...

  1. Analysing Discursive Practices in Legal Research : How a Single Remark Implies a Paradigm

    NARCIS (Netherlands)

    van den Hoven, P.J.

    2017-01-01

    Different linguistic theories of meaning (semantic theories) imply different methods to discuss meaning. Discussing meaning is what legal practitioners frequently do to decide legal issues and, subsequently, legal scholars analyse in their studies these discursive practices of parties, judges and

  2. Market-implied risk-neutral probabilities, actual probabilities, credit risk and news

    Directory of Open Access Journals (Sweden)

    Shashidhar Murthy

    2011-09-01

    Full Text Available Motivated by the credit crisis, this paper investigates links between risk-neutral probabilities of default implied by markets (e.g. from yield spreads and their actual counterparts (e.g. from ratings. It discusses differences between the two and clarifies underlying economic intuition using simple representations of credit risk pricing. Observed large differences across bonds in the ratio of the two probabilities are shown to imply that apparently safer securities can be more sensitive to news.

  3. Can we replace CAPM and the Three-Factor model with Implied Cost of Capital?

    OpenAIRE

    Löthman, Robert; Pettersson, Eric

    2014-01-01

    Researchers criticize predominant expected return models for being imprecise and based on fundamentally flawed assumptions. This dissertation evaluates Implied Cost of Capital, CAPM and the Three-Factor model abilities to estimate returns. We study each models expected return association to realized return and test for abnormal returns. Our sample covers the period 2000 to 2012 and includes 2916 US firms. We find that Implied Cost of Capital has a stronger association with realized returns th...

  4. LEFT-WING ASYMPTOTICS OF THE IMPLIED VOLATILITY IN THE PRESENCE OF ATOMS

    OpenAIRE

    ARCHIL GULISASHVILI

    2015-01-01

    The paper considers the asymptotic behavior of the implied volatility in stochastic asset price models with atoms. In such models, the asset price distribution has a singular component at zero. Examples of models with atoms include the constant elasticity of variance (CEV) model, jump-to-default models, and stochastic models described by processes stopped at the first hitting time of zero. For models with atoms, the behavior of the implied volatility at large strikes is similar to that in mod...

  5. Relationship of the change in implied volatility with the underlying equity index return in Thailand

    OpenAIRE

    Thakolsri, Supachock; Sethapramote, Yuthana; Jiranyakul, Komain

    2016-01-01

    In this study, we examine the relationship between the change in implied volatility index and the underlying stock index return in the Thai stock market. The data used are daily data during November 2010 to December 2013. The regression analysis is performed on stationary series. The empirical results reveal that there is evidence of a significantly negative and asymmetric relationship between the underlying stock index return and the change in implied volatility. The finding in this study gi...

  6. Modeling and Forecasting the Implied Volatility of the WIG20 Index

    OpenAIRE

    Buszkowska-Khemissi, Eliza; Płuciennik, Piotr

    2007-01-01

    The implied volatility is one of the most important notions in the financial market. It informs about the volatility forecasted by the participans of the market. In this paper we calculate the daily implied volatility from options on the WIG20 index. First we test the long memory property of the time series obtained in such a way, and then we model and forcast it as ARFIMA process

  7. Bayesian Forecasting of Options Prices: A Natural Framework for Pooling Historical and Implied Volatiltiy Information

    OpenAIRE

    Darsinos, T.; Satchell, S.E.

    2001-01-01

    Bayesian statistical methods are naturally oriented towards pooling in a rigorous way information from separate sources. It has been suggested that both historical and implied volatilities convey information about future volatility. However, typically in the literature implied and return volatility series are fed separately into models to provide rival forecasts of volatility or options prices. We develop a formal Bayesian framework where we can merge the backward looking information as r...

  8. Motor mapping of implied actions during perception of emotional body language.

    Science.gov (United States)

    Borgomaneri, Sara; Gazzola, Valeria; Avenanti, Alessio

    2012-04-01

    Perceiving and understanding emotional cues is critical for survival. Using the International Affective Picture System (IAPS) previous TMS studies have found that watching humans in emotional pictures increases motor excitability relative to seeing landscapes or household objects, suggesting that emotional cues may prime the body for action. Here we tested whether motor facilitation to emotional pictures may reflect the simulation of the human motor behavior implied in the pictures occurring independently of its emotional valence. Motor-evoked potentials (MEPs) to single-pulse TMS of the left motor cortex were recorded from hand muscles during observation and categorization of emotional and neutral pictures. In experiment 1 participants watched neutral, positive and negative IAPS stimuli, while in experiment 2, they watched pictures depicting human emotional (joyful, fearful), neutral body movements and neutral static postures. Experiment 1 confirms the increase in excitability for emotional IAPS stimuli found in previous research and shows, however, that more implied motion is perceived in emotional relative to neutral scenes. Experiment 2 shows that motor excitability and implied motion scores for emotional and neutral body actions were comparable and greater than for static body postures. In keeping with embodied simulation theories, motor response to emotional pictures may reflect the simulation of the action implied in the emotional scenes. Action simulation may occur independently of whether the observed implied action carries emotional or neutral meanings. Our study suggests the need of controlling implied motion when exploring motor response to emotional pictures of humans. Copyright © 2012 Elsevier Inc. All rights reserved.

  9. Implied adjusted volatility functions: Empirical evidence from Australian index option market

    Science.gov (United States)

    Harun, Hanani Farhah; Hafizah, Mimi

    2015-02-01

    This study aims to investigate the implied adjusted volatility functions using the different Leland option pricing models and to assess whether the use of the specified implied adjusted volatility function can lead to an improvement in option valuation accuracy. The implied adjusted volatility is investigated in the context of Standard and Poor/Australian Stock Exchange (S&P/ASX) 200 index options over the course of 2001-2010, which covers the global financial crisis in the mid-2007 until the end of 2008. Both in- and out-of-sample resulted in approximately similar pricing error along the different Leland models. Results indicate that symmetric and asymmetric models of both moneyness ratio and logarithmic transformation of moneyness provide the overall best result in both during and post-crisis periods. We find that in the different period of interval (pre-, during and post-crisis) is subject to a different implied adjusted volatility function which best explains the index options. Hence, it is tremendously important to identify the intervals beforehand in investigating the implied adjusted volatility function.

  10. Analysing Discursive Practices in Legal Research: How a Single Remark Implies a Paradigm

    Directory of Open Access Journals (Sweden)

    Paul van den Hoven

    2017-12-01

    Full Text Available Different linguistic theories of meaning (semantic theories imply different methods to discuss meaning. Discussing meaning is what legal practitioners frequently do to decide legal issues and, subsequently, legal scholars analyse in their studies these discursive practices of parties, judges and legal experts. Such scholarly analysis reveals a methodical choice on how to discuss meaning and therefore implies positioning oneself towards a semantic theory of meaning, whether the scholar is aware of this or not. Legal practitioners may not be bound to be consistent in their commitment to semantic theories, as their task is to decide legal issues. Legal scholars, however, should be consistent because commitment to a semantic theory implies a distinct position towards important legal theoretical doctrines. In this paper three examples are discussed that require an articulated position of the legal scholar because the discursive practices of legal practitioners show inconsistencies. For each of these examples it can be shown that a scholar’s methodic choice implies commitment to a specific semantic theory, and that adopting such a theory implies a distinct position towards the meaning of the Rule of Law, the separation of powers doctrine and the institutional position of the judge.

  11. The Impact of Jump Distributions on the Implied Volatility of Variance

    DEFF Research Database (Denmark)

    Nicolato, Elisa; Pisani, Camilla; Pedersen, David Sloth

    2017-01-01

    We consider a tractable affine stochastic volatility model that generalizes the seminal Heston (1993) model by augmenting it with jumps in the instantaneous variance process. In this framework, we consider both realized variance options and VIX options, and we examine the impact of the distribution...... of jumps on the associated implied volatility smile. We provide sufficient conditions for the asymptotic behavior of the implied volatility of variance for small and large strikes. In particular, by selecting alternative jump distributions, we show that one can obtain fundamentally different shapes...

  12. Moment generating functions and Normalized implied volatilities: unification and extension via Fukasawa's pricing formula

    OpenAIRE

    De Marco, Stefano; Martini, Claude

    2017-01-01

    We extend the model-free formula of [Fukasawa 2012] for $\\mathbb E[\\Psi(X_T)]$, where $X_T=\\log S_T/F$ is the log-price of an asset, to functions $\\Psi$ of exponential growth. The resulting integral representation is written in terms of normalized implied volatilities. Just as Fukasawa's work provides rigourous ground for Chriss and Morokoff's (1999) model-free formula for the log-contract (related to the Variance swap implied variance), we prove an expression for the moment generating functi...

  13. An Hilbert space approach for a class of arbitrage free implied volatilities models

    OpenAIRE

    Brace, A.; Fabbri, G.; Goldys, B.

    2007-01-01

    We present an Hilbert space formulation for a set of implied volatility models introduced in \\cite{BraceGoldys01} in which the authors studied conditions for a family of European call options, varying the maturing time and the strike price $T$ an $K$, to be arbitrage free. The arbitrage free conditions give a system of stochastic PDEs for the evolution of the implied volatility surface ${\\hat\\sigma}_t(T,K)$. We will focus on the family obtained fixing a strike $K$ and varying $T$. In order to...

  14. Size Does Matter: Implied Object Size is Mentally Simulated During Language Comprehension

    NARCIS (Netherlands)

    de Koning, Bjorn B.; Wassenburg, Stephanie I.; Bos, Lisanne T.; Van der Schoot, Menno

    2017-01-01

    Embodied theories of language comprehension propose that readers construct a mental simulation of described objects that contains perceptual characteristics of their real-world referents. The present study is the first to investigate directly whether implied object size is mentally simulated during

  15. The Effect of Implied Performer Age and Group Membership on Evaluations of Music Performances

    Science.gov (United States)

    Harrington, Ann M.

    2018-01-01

    This study examined the effects of implied performer age and group membership on listeners' evaluations of music performances. Undergraduate music majors (n = 23), nonmusic majors (n = 17), and members of a New Horizons ensemble (n = 16) were presented with six 30-second excerpts of concert band performances. Excerpts were presented to all…

  16. Covariance of time-ordered products implies local commutativity of fields

    International Nuclear Information System (INIS)

    Greenberg, O.W.

    2006-01-01

    We formulate Lorentz covariance of a quantum field theory in terms of covariance of time-ordered products (or other Green's functions). This formulation of Lorentz covariance implies spacelike local commutativity or anticommutativity of fields, sometimes called microscopic causality or microcausality. With this formulation microcausality does not have to be taken as a separate assumption

  17. Latent Integrated Stochastic Volatility, Realized Volatility, and Implied Volatility: A State Space Approach

    DEFF Research Database (Denmark)

    Bach, Christian; Christensen, Bent Jesper

    process is downward biased. Implied volatility performs better than any of the alternative realized measures when forecasting future integrated volatility. The results are largely similar across the stock market (S&P 500), bond market (30-year U.S. T-bond), and foreign currency exchange market ($/£ )....

  18. No, Virginia, It's Not True What They Say About Publicity's "Implied Third-Party Endorsement" Effect.

    Science.gov (United States)

    Hallahan, Kirk

    1999-01-01

    Re-examines "implied third-party endorsement" as an explanation of publicity's effectiveness. Argues that any effect involves inferences by audience members who use biased processing that favors news and disfavors advertising. Suggests that the presentation of information as news is not necessarily perceived by audiences as an…

  19. Implied Volatility of Interest Rate Options: An Empirical Investigation of the Market Model

    DEFF Research Database (Denmark)

    Christiansen, Charlotte; Hansen, Charlotte Strunk

    2002-01-01

    We analyze the empirical properties of the volatility implied in options on the 13-week US Treasury bill rate. These options have not been studied previously. It is shown that a European style put option on the interest rate is equivalent to a call option on a zero-coupon bond. We apply the LIBOR...

  20. Level Shifts in Volatility and the Implied-Realized Volatility Relation

    DEFF Research Database (Denmark)

    Christensen, Bent Jesper; de Magistris, Paolo Santucci

    We propose a simple model in which realized stock market return volatility and implied volatility backed out of option prices are subject to common level shifts corresponding to movements between bull and bear markets. The model is estimated using the Kalman filter in a generalization to the mult......We propose a simple model in which realized stock market return volatility and implied volatility backed out of option prices are subject to common level shifts corresponding to movements between bull and bear markets. The model is estimated using the Kalman filter in a generalization...... to the multivariate case of the univariate level shift technique by Lu and Perron (2008). An application to the S&P500 index and a simulation experiment show that the recently documented empirical properties of strong persistence in volatility and forecastability of future realized volatility from current implied...... volatility, which have been interpreted as long memory (or fractional integration) in volatility and fractional cointegration between implied and realized volatility, are accounted for by occasional common level shifts....

  1. Asymptotic Expansions of the Lognormal Implied Volatility : A Model Free Approach

    OpenAIRE

    Cyril Grunspan

    2011-01-01

    We invert the Black-Scholes formula. We consider the cases low strike, large strike, short maturity and large maturity. We give explicitly the first 5 terms of the expansions. A method to compute all the terms by induction is also given. At the money, we have a closed form formula for implied lognormal volatility in terms of a power series in call price.

  2. Aplikasi Algoritma Biseksi dan Newton-Raphson dalam Menaksir Nilai Volatilitas Implied

    Directory of Open Access Journals (Sweden)

    Komang Dharmawan

    2012-11-01

    Full Text Available Volatilitas adalah suatu besaran yang mengukuran seberapa jauh suatu harga sahambergerak dalam suatu periode tertentu dapat juga diartikan sebagai persentase simpanganbaku dari perubahan harga harian suatu saham. Menurut teori yang dikembangkan oleh Black-Scholes in 1973, semua harga opsi dengan ’underlying asset’ dan waktu jatuh tempo yang samatetapi memiliki nilai exercise yang berbeda akan memiliki nilai volatilitas implied yang sama.Model Black-Scholes dapat dipakai mengestimasi nilai volatilitas implied dari suatu sahamdengan mencari sulusi numerik dari persamaan invers dari model Black-Scholes. Makalah inimendemonstrasikan bagaimana menghitung nilai volatilitas implied suatu saham dengan mengasumsikanbahwa model Black-schole adalah benar dan suatu kontrak opsi dengan denganumur kontrak yang sama akan memiliki harga yang sama. Menggunakan data harga opsi SonyCorporation (SNE, Cisco Systems, Inc (CSCO, dan Canon, Inc (CNJ diperoleh bahwa, ImpliedVolatility memberikan harga yang lebih murah dibandingkan dengan harga opsi darivolatilitas yang dihitung dari data historis. Selain itu, dari hasil iterasi yang diperoleh, metodeNewton-Raphson lebih cepat konvergen dibandingkan dengan metode Bisection.

  3. A Note on the Equivalence between the Normal and the Lognormal Implied Volatility : A Model Free Approach

    OpenAIRE

    Grunspan, Cyril

    2011-01-01

    First, we show that implied normal volatility is intimately linked with the incomplete Gamma function. Then, we deduce an expansion on implied normal volatility in terms of the time-value of a European call option. Then, we formulate an equivalence between the implied normal volatility and the lognormal implied volatility with any strike and any model. This generalizes a known result for the SABR model. Finally, we adress the issue of the "breakeven move" of a delta-hedged portfolio.

  4. Revisiting the long memory dynamics of implied-realized volatility relation: A new evidence from wavelet band spectrum regression

    OpenAIRE

    Barunik, Jozef; Barunikova, Michaela

    2015-01-01

    This paper revisits the fractional co-integrating relationship between ex-ante implied volatility and ex-post realized volatility. Previous studies on stock index options have found biases and inefficiencies in implied volatility as a forecast of future volatility. It is argued that the concept of corridor implied volatility (CIV) should be used instead of the popular model-free option-implied volatility (MFIV) when assessing the relation as the latter may introduce bias to the estimation. In...

  5. Does “quorum sensing” imply a new type of biological information?

    DEFF Research Database (Denmark)

    Bruni, Luis Emilio

    2002-01-01

    When dealing with biological communication and information, unifying concepts are necessary in order to couple the different “codes” that are being inductively “cracked” and defined at different emergent and “de-emergent” levels of the biological hierarchy. In this paper I compare the type...... of biological information implied by genetic information with that implied in the concept of “quorum sensing” (which refers to a prokaryotic cell-to-cell communication system) in order to explore if such integration is being achieved. I use the Lux operon paradigm and the Vibrio fischeri – Euprymna scolopes...... symbiotic partnership to exemplify the emergence of informational contexts along the biological hierarchy (from molecules to ecologies). I suggest that the biosemiotic epistemological framework can play an integra¬tive role to overcome the limits of dyadic mechanistic descriptions when relating...

  6. Individual chaos implies collective chaos for weakly mixing discrete dynamical systems

    International Nuclear Information System (INIS)

    Liao Gongfu; Ma Xianfeng; Wang Lidong

    2007-01-01

    Let X be a metric space (X,f) a discrete dynamical system, where f:X->X is a continuous function. Let f-bar denote the natural extension of f to the space of all non-empty compact subsets of X endowed with Hausdorff metric induced by d. In this paper we investigate some dynamical properties of f and f-bar . It is proved that f is weakly mixing (mixing) if and only if f-bar is weakly mixing (mixing, respectively). From this, we deduce that weak-mixing of f implies transitivity of f-bar , further, if f is mixing or weakly mixing, then chaoticity of f (individual chaos) implies chaoticity of f-bar (collective chaos) and if X is a closed interval then f-bar is chaotic (in the sense of Devaney) if and only if f is weakly mixing

  7. PERBANDINGAN KEEFISIENAN METODE NEWTON-RAPHSON, METODE SECANT, DAN METODE BISECTION DALAM MENGESTIMASI IMPLIED VOLATILITIES SAHAM

    Directory of Open Access Journals (Sweden)

    IDA AYU EGA RAHAYUNI

    2016-01-01

    Full Text Available Black-Scholes model suggests that volatility is constant or fixed during the life time of the option certainly known. However, this does not fit with what happen in the real market. Therefore, the volatility has to be estimated. Implied Volatility is the etimated volatility from a market mechanism that is considered as a reasonable way to assess the volatility's value. This study was aimed to compare the Newton-Raphson, Secant, and Bisection method, in estimating the stock volatility value of PT Telkom Indonesia Tbk (TLK. It found that the three methods have the same Implied Volatilities, where Newton-Raphson method gained roots more rapidly than the two others, and it has the smallest relative error greater than Secant and Bisection methods.

  8. Selecting the Best Forecasting-Implied Volatility Model Using Genetic Programming

    Directory of Open Access Journals (Sweden)

    Wafa Abdelmalek

    2009-01-01

    Full Text Available The volatility is a crucial variable in option pricing and hedging strategies. The aim of this paper is to provide some initial evidence of the empirical relevance of genetic programming to volatility's forecasting. By using real data from S&P500 index options, the genetic programming's ability to forecast Black and Scholes-implied volatility is compared between time series samples and moneyness-time to maturity classes. Total and out-of-sample mean squared errors are used as forecasting's performance measures. Comparisons reveal that the time series model seems to be more accurate in forecasting-implied volatility than moneyness time to maturity models. Overall, results are strongly encouraging and suggest that the genetic programming approach works well in solving financial problems.

  9. The Short-Time Behaviour of VIX Implied Volatilities in a Multifactor Stochastic Volatility Framework

    DEFF Research Database (Denmark)

    Barletta, Andrea; Nicolato, Elisa; Pagliarani, Stefano

    error bounds for VIX futures, options and implied volatilities. In particular, we derive exact asymptotic results for VIX implied volatilities, and their sensitivities, in the joint limit of short time-to-maturity and small log-moneyness. The obtained expansions are explicit, based on elementary...... approximations of equity (SPX) options. However, the generalizations needed to cover the case of VIX options are by no means straightforward as the dynamics of the underlying VIX futures are not explicitly known. To illustrate the accuracy of our technique, we provide numerical implementations for a selection...... functions and they neatly uncover how the VIX skew depends on the specific choice of the volatility and the vol-of-vol processes. Our results are based on perturbation techniques applied to the infinitesimal generator of the underlying process. This methodology has been previously adopted to derive...

  10. Women’s stories implying aspects of anti-Judaism with Christological depiction in Matthew

    Directory of Open Access Journals (Sweden)

    In-Cheol Shin

    2014-10-01

    Full Text Available This study focuses on the women’s stories that imply aspects of anti-Judaism within Matthew’s depiction of Christology, which is called Matthew’s theology. In fact, Matthew’s community opposed the Jewish system and Jewish leaders and parted from its parent body. Even though Matthew’s community was still similar to the Jewish system, it had significant differences as well. The study discusses these aspects of anti-Judaism that appear in the woman’s stories that include the genealogy of Jesus, the haemorrhaging woman, the Canaanite woman, and the women at the cross and Jesus’ tomb. This study shows proof and examples of anti-Judaism within the stories and thoroughly analyses them. Therefore, it can be confirmed that the women’s stories imply aspects of anti-Judaism with Christological depictions by Matthew’s theological tendency.

  11. No-Arbitrage Condition of Option Implied Volatility and Bandwidth Selection

    Czech Academy of Sciences Publication Activity Database

    Kopa, Miloš; Tichý, T.

    2014-01-01

    Roč. 17, č. 3 (2014), s. 751-755 ISSN 0972-0073 R&D Projects: GA ČR(CZ) GA13-25911S Institutional support: RVO:67985556 Keywords : Option Pricing * Implied Volatility * DAX Index * Local polynomial smoothing Subject RIV: AH - Economics Impact factor: 0.222, year: 2014 http://library.utia.cas.cz/separaty/2014/E/kopa-0429805.pdf

  12. HISTORICAL AND IMPLIED VOLATILITY: AN INVESTIGATION INTO NSE NIFTY FUTURES AND OPTIONS

    OpenAIRE

    N R Parasuraman; P.Janaki Ramudu

    2011-01-01

    The broad objective of the paper is to have an understanding of the movement of volatility over a fair period in respect of the market portfolio. Also, it enables an understanding on how divergent the implied volatility has been from this estimate. It uses Volatility Cone, Volatility Smile and Volatility Surface as the parameters. The study takes different rolling periods percentiles of volatility. Hoadley Options Calculator is used for calculation and analysis purpose. The study empirically...

  13. Portfolio Optimization under Local-Stochastic Volatility: Coefficient Taylor Series Approximations & Implied Sharpe Ratio

    OpenAIRE

    Lorig, Matthew; Sircar, Ronnie

    2015-01-01

    We study the finite horizon Merton portfolio optimization problem in a general local-stochastic volatility setting. Using model coefficient expansion techniques, we derive approximations for the both the value function and the optimal investment strategy. We also analyze the `implied Sharpe ratio' and derive a series approximation for this quantity. The zeroth-order approximation of the value function and optimal investment strategy correspond to those obtained by Merton (1969) when the risky...

  14. Predictable dynamics in implied volatility smirk slope : evidence from the S&P 500 options

    OpenAIRE

    Onan, Mustafa

    2012-01-01

    Ankara : The Department of Management, İhsan Doğramacı Bilkent University, 2012. Thesis (Master's) -- Bilkent University, 2012. Includes bibliographical references. This study aims to investigate whether there are predictable patterns in the dynamics of implied volatility smirk slopes extracted from the intraday market prices of S&P 500 index options. I compare forecasts obtained from a short memory ARMA model and a long memory ARFIMA model within an out-of-sample context ov...

  15. How "ought" exceeds but implies "can": Description and encouragement in moral judgment.

    Science.gov (United States)

    Turri, John

    2017-11-01

    This paper tests a theory about the relationship between two important topics in moral philosophy and psychology. One topic is the function of normative language, specifically claims that one "ought" to do something. Do these claims function to describe moral responsibilities, encourage specific behavior, or both? The other topic is the relationship between saying that one "ought" to do something and one's ability to do it. In what respect, if any, does what one "ought" to do exceed what one "can" do? The theory tested here has two parts: (1) "ought" claims function to both describe responsibilities and encourage people to fulfill them (the dual-function hypothesis); (2) the two functions relate differently to ability, because the encouragement function is limited by the person's ability, but the descriptive function is not (the interaction hypothesis). If this theory is correct, then in one respect "ought implies can" is false because people have responsibilities that exceed their abilities. But in another respect "ought implies can" is legitimate because it is not worthwhile to encourage people to do things that exceed their ability. Results from two behavioral experiments support the theory that "ought" exceeds but implies "can." Results from a third experiment provide further evidence regarding an "ought" claim's primary function and how contextual features can affect the interpretation of its functions. Copyright © 2017 Elsevier B.V. All rights reserved.

  16. Implied and Local Volatility Surfaces for South African Index and Foreign Exchange Options

    Directory of Open Access Journals (Sweden)

    Antonie Kotzé

    2015-01-01

    Full Text Available Certain exotic options cannot be valued using closed-form solutions or even by numerical methods assuming constant volatility. Many exotics are priced in a local volatility framework. Pricing under local volatility has become a field of extensive research in finance, and various models are proposed in order to overcome the shortcomings of the Black-Scholes model that assumes a constant volatility. The Johannesburg Stock Exchange (JSE lists exotic options on its Can-Do platform. Most exotic options listed on the JSE’s derivative exchanges are valued by local volatility models. These models needs a local volatility surface. Dupire derived a mapping from implied volatilities to local volatilities. The JSE uses this mapping in generating the relevant local volatility surfaces and further uses Monte Carlo and Finite Difference methods when pricing exotic options. In this document we discuss various practical issues that influence the successful construction of implied and local volatility surfaces such that pricing engines can be implemented successfully. We focus on arbitrage-free conditions and the choice of calibrating functionals. We illustrate our methodologies by studying the implied and local volatility surfaces of South African equity index and foreign exchange options.

  17. A Dynamical Model of Pitch Memory Provides an Improved Basis for Implied Harmony Estimation

    Science.gov (United States)

    Kim, Ji Chul

    2017-01-01

    Tonal melody can imply vertical harmony through a sequence of tones. Current methods for automatic chord estimation commonly use chroma-based features extracted from audio signals. However, the implied harmony of unaccompanied melodies can be difficult to estimate on the basis of chroma content in the presence of frequent nonchord tones. Here we present a novel approach to automatic chord estimation based on the human perception of pitch sequences. We use cohesion and inhibition between pitches in auditory short-term memory to differentiate chord tones and nonchord tones in tonal melodies. We model short-term pitch memory as a gradient frequency neural network, which is a biologically realistic model of auditory neural processing. The model is a dynamical system consisting of a network of tonotopically tuned nonlinear oscillators driven by audio signals. The oscillators interact with each other through nonlinear resonance and lateral inhibition, and the pattern of oscillatory traces emerging from the interactions is taken as a measure of pitch salience. We test the model with a collection of unaccompanied tonal melodies to evaluate it as a feature extractor for chord estimation. We show that chord tones are selectively enhanced in the response of the model, thereby increasing the accuracy of implied harmony estimation. We also find that, like other existing features for chord estimation, the performance of the model can be improved by using segmented input signals. We discuss possible ways to expand the present model into a full chord estimation system within the dynamical systems framework. PMID:28522983

  18. A Dynamical Model of Pitch Memory Provides an Improved Basis for Implied Harmony Estimation.

    Science.gov (United States)

    Kim, Ji Chul

    2017-01-01

    Tonal melody can imply vertical harmony through a sequence of tones. Current methods for automatic chord estimation commonly use chroma-based features extracted from audio signals. However, the implied harmony of unaccompanied melodies can be difficult to estimate on the basis of chroma content in the presence of frequent nonchord tones. Here we present a novel approach to automatic chord estimation based on the human perception of pitch sequences. We use cohesion and inhibition between pitches in auditory short-term memory to differentiate chord tones and nonchord tones in tonal melodies. We model short-term pitch memory as a gradient frequency neural network, which is a biologically realistic model of auditory neural processing. The model is a dynamical system consisting of a network of tonotopically tuned nonlinear oscillators driven by audio signals. The oscillators interact with each other through nonlinear resonance and lateral inhibition, and the pattern of oscillatory traces emerging from the interactions is taken as a measure of pitch salience. We test the model with a collection of unaccompanied tonal melodies to evaluate it as a feature extractor for chord estimation. We show that chord tones are selectively enhanced in the response of the model, thereby increasing the accuracy of implied harmony estimation. We also find that, like other existing features for chord estimation, the performance of the model can be improved by using segmented input signals. We discuss possible ways to expand the present model into a full chord estimation system within the dynamical systems framework.

  19. Allocentrically implied target locations are updated in an eye-centred reference frame.

    Science.gov (United States)

    Thompson, Aidan A; Glover, Christopher V; Henriques, Denise Y P

    2012-04-18

    When reaching to remembered target locations following an intervening eye movement a systematic pattern of error is found indicating eye-centred updating of visuospatial memory. Here we investigated if implicit targets, defined only by allocentric visual cues, are also updated in an eye-centred reference frame as explicit targets are. Participants viewed vertical bars separated by varying distances, and horizontal lines of equivalently varying lengths, implying a "target" location at the midpoint of the stimulus. After determining the implied "target" location from only the allocentric stimuli provided, participants saccaded to an eccentric location, and reached to the remembered "target" location. Irrespective of the type of stimulus reaching errors to these implicit targets are gaze-dependent, and do not differ from those found when reaching to remembered explicit targets. Implicit target locations are coded and updated as a function of relative gaze direction with respect to those implied locations just as explicit targets are, even though no target is specifically represented. Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.

  20. A Dynamical Model of Pitch Memory Provides an Improved Basis for Implied Harmony Estimation

    Directory of Open Access Journals (Sweden)

    Ji Chul Kim

    2017-05-01

    Full Text Available Tonal melody can imply vertical harmony through a sequence of tones. Current methods for automatic chord estimation commonly use chroma-based features extracted from audio signals. However, the implied harmony of unaccompanied melodies can be difficult to estimate on the basis of chroma content in the presence of frequent nonchord tones. Here we present a novel approach to automatic chord estimation based on the human perception of pitch sequences. We use cohesion and inhibition between pitches in auditory short-term memory to differentiate chord tones and nonchord tones in tonal melodies. We model short-term pitch memory as a gradient frequency neural network, which is a biologically realistic model of auditory neural processing. The model is a dynamical system consisting of a network of tonotopically tuned nonlinear oscillators driven by audio signals. The oscillators interact with each other through nonlinear resonance and lateral inhibition, and the pattern of oscillatory traces emerging from the interactions is taken as a measure of pitch salience. We test the model with a collection of unaccompanied tonal melodies to evaluate it as a feature extractor for chord estimation. We show that chord tones are selectively enhanced in the response of the model, thereby increasing the accuracy of implied harmony estimation. We also find that, like other existing features for chord estimation, the performance of the model can be improved by using segmented input signals. We discuss possible ways to expand the present model into a full chord estimation system within the dynamical systems framework.

  1. A reporting system for endometrial cytology: Cytomorphologic criteria-Implied risk of malignancy.

    Science.gov (United States)

    Margari, Niki; Pouliakis, Abraham; Anoinos, Dionysios; Terzakis, Emmanouil; Koureas, Nikolaos; Chrelias, Charalampos; Marios Makris, George; Pappas, Assimakis; Bilirakis, Evripidis; Goudeli, Christina; Damaskou, Vasileia; Papantoniou, Nicolaos; Panayiotides, Ioannis; Karakitsos, Petros

    2016-11-01

    There have been various attempts to assess endometrial lesions on cytological material obtained via direct endometrial sampling. The majority of efforts focus on the description of cytological criteria that lead to classification systems resembling histological reporting formats. These systems have low reproducibility, especially in cases of atypical hyperplasia and well differentiated carcinomas. Moreover, they are not linked to the implied risk of malignancy. The material was collected from women examined at the outpatient department of four participating hospitals. We analyzed 866 consecutive, histologically confirmed cases. The sample collection was performed using the EndoGyn device, and processed via Liquid Based Cytology, namely ThinPrep technique. The diagnostic categories and criteria were established by two cytopathologists experienced in endometrial cytology; performance of the proposed reporting format was assessed on the basis of histological outcome; moreover, the implied risk of malignancy was calculated. The proposed six diagnostic categories are as follows: (i) nondiagnostic or unsatisfactory; (ii) without evidence of hyperplasia or malignancy; (iii) atypical cells of endometrium of undetermined significance; (iv) atypical cells of endometrium of low probability for malignancy; (v) atypical cells of endometrium of high probability for malignancy; and (vi) malignant. The risk of malignancy was 1.42% ± 0.98%, 44.44% ± 32.46% (nine cases), 4.30% ± 4.12%, 89.80% ± 8.47%, and 97.81% ± 2.45%, respectively. We propose a clinically oriented classification scheme consisting of diagnostic categories with well determined criteria. Each diagnostic category is linked with an implied risk of malignancy; thus, clinicians may decide on patient management and eventually reduce unnecessary interventional diagnostic procedures. Diagn. Cytopathol. 2016;44:888-901. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  2. Negative masses, even if isolated, imply self-acceleration, hence a catastrophic world

    International Nuclear Information System (INIS)

    Cavalleri, G.; Tonni, E.

    1997-01-01

    The conjecture of the existence of negative masses together with ordinary positive masses leads to runaway motions even if no self-reaction is considered. Pollard and Dunning-Davies have shown other constraints as a modification of the principle of least action and that negative masses can only exist at negative temperature, and must be adiabatically separate from positive masses. They show here that the self-reaction on a single isolated negative mass implies a runaway motion. Consequently, the consideration of self-fields and relevant self-reaction excludes negative masses even if isolated

  3. Large deviations and stochastic volatility with jumps: asymptotic implied volatility for affine models

    OpenAIRE

    Antoine Jacquier; Martin Keller-Ressel; Aleksandar Mijatovic

    2011-01-01

    Let $\\sigma_t(x)$ denote the implied volatility at maturity $t$ for a strike $K=S_0 e^{xt}$, where $x\\in\\bbR$ and $S_0$ is the current value of the underlying. We show that $\\sigma_t(x)$ has a uniform (in $x$) limit as maturity $t$ tends to infinity, given by the formula $\\sigma_\\infty(x)=\\sqrt{2}(h^*(x)^{1/2}+(h^*(x)-x)^{1/2})$, for $x$ in some compact neighbourhood of zero in the class of affine stochastic volatility models. The function $h^*$ is the convex dual of the limiting cumulant gen...

  4. VaR and CVaR Implied in Option Prices

    Directory of Open Access Journals (Sweden)

    Giovanni Barone Adesi

    2016-02-01

    Full Text Available VaR (Value at Risk and CVaR (Conditional Value at Risk are implied by option prices. Their relationships to option prices are derived initially under the pricing measure. It does not require assumptions about the distribution of portfolio returns. The effects of changes of measure are modest at the short horizons typically used in applications. The computation of CVaR from option price is very convenient, because this measure is not elicitable, making direct comparisons of statistical inferences from market data problematic.

  5. Large fault fabric of the Ninetyeast Ridge implies near-spreading ridge formation

    Digital Repository Service at National Institute of Oceanography (India)

    Sager, W.W.; Paul, C.F.; Krishna, K.S.; Pringle, M.S.; Eisin, A.E.; Frey, F.A.; Rao, D.G.; Levchenko, O.V.

    of the high ridge. At 26°S, prominent NE-SW 97 oriented lineations extend southwest from the ridge. Some appear to connect with N-S fracture 98 zone troughs east of NER, implying that the NE-SW features are fracture zone scars formed after 99 the change... to the 105 ridge (Fig. 3). This is especially true for NER south of ~4°S. Where KNOX06RR crossed a 106 gravity lineation, negative gradient features correspond to troughs whereas positive gradient 107 features result from igneous basement highs (Fig. 3...

  6. Asymptotic Behavior of the Stock Price Distribution Density and Implied Volatility in Stochastic Volatility Models

    International Nuclear Information System (INIS)

    Gulisashvili, Archil; Stein, Elias M.

    2010-01-01

    We study the asymptotic behavior of distribution densities arising in stock price models with stochastic volatility. The main objects of our interest in the present paper are the density of time averages of the squared volatility process and the density of the stock price process in the Stein-Stein and the Heston model. We find explicit formulas for leading terms in asymptotic expansions of these densities and give error estimates. As an application of our results, sharp asymptotic formulas for the implied volatility in the Stein-Stein and the Heston model are obtained.

  7. Scalar utility theory and proportional processing: What does it actually imply?

    Science.gov (United States)

    Rosenström, Tom; Wiesner, Karoline; Houston, Alasdair I

    2016-09-07

    Scalar Utility Theory (SUT) is a model used to predict animal and human choice behaviour in the context of reward amount, delay to reward, and variability in these quantities (risk preferences). This article reviews and extends SUT, deriving novel predictions. We show that, contrary to what has been implied in the literature, (1) SUT can predict both risk averse and risk prone behaviour for both reward amounts and delays to reward depending on experimental parameters, (2) SUT implies violations of several concepts of rational behaviour (e.g. it violates strong stochastic transitivity and its equivalents, and leads to probability matching) and (3) SUT can predict, but does not always predict, a linear relationship between risk sensitivity in choices and coefficient of variation in the decision-making experiment. SUT derives from Scalar Expectancy Theory which models uncertainty in behavioural timing using a normal distribution. We show that the above conclusions also hold for other distributions, such as the inverse Gaussian distribution derived from drift-diffusion models. A straightforward way to test the key assumptions of SUT is suggested and possible extensions, future prospects and mechanistic underpinnings are discussed. Copyright © 2016 Elsevier Ltd. All rights reserved.

  8. Effects of Implied Motion and Facing Direction on Positional Preferences in Single-Object Pictures.

    Science.gov (United States)

    Palmer, Stephen E; Langlois, Thomas A

    2017-07-01

    Palmer, Gardner, and Wickens studied aesthetic preferences for pictures of single objects and found a strong inward bias: Right-facing objects were preferred left-of-center and left-facing objects right-of-center. They found no effect of object motion (people and cars showed the same inward bias as chairs and teapots), but the objects were not depicted as moving. Here we measured analogous inward biases with objects depicted as moving with an implied direction and speed by having participants drag-and-drop target objects into the most aesthetically pleasing position. In Experiment 1, human figures were shown diving or falling while moving forward or backward. Aesthetic biases were evident for both inward-facing and inward-moving figures, but the motion-based bias dominated so strongly that backward divers or fallers were preferred moving inward but facing outward. Experiment 2 investigated implied speed effects using images of humans, horses, and cars moving at different speeds (e.g., standing, walking, trotting, and galloping horses). Inward motion or facing biases were again present, and differences in their magnitude due to speed were evident. Unexpectedly, faster moving objects were generally preferred closer to frame center than slower moving objects. These results are discussed in terms of the combined effects of prospective, future-oriented biases, and retrospective, past-oriented biases.

  9. Transformations of visual memory induced by implied motions of pattern elements.

    Science.gov (United States)

    Finke, R A; Freyd, J J

    1985-10-01

    Four experiments measured distortions in short-term visual memory induced by displays depicting independent translations of the elements of a pattern. In each experiment, observers saw a sequence of 4 dot patterns and were instructed to remember the third pattern and to compare it with the fourth. The first three patterns depicted translations of the dots in consistent, but separate directions. Error rates and reaction times for rejecting the fourth pattern as different from the third were substantially higher when the dots in that pattern were displaced slightly forward, in the same directions as the implied motions, compared with when the dots were displaced in the opposite, backward directions. These effects showed little variation across interstimulus intervals ranging from 250 to 2,000 ms, and did not depend on whether the displays gave rise to visual apparent motion. However, they were eliminated when the dots in the fourth pattern were displaced by larger amounts in each direction, corresponding to the dot positions in the next and previous patterns in the same inducing sequence. These findings extend our initial report of the phenomenon of "representational momentum" (Freyd & Finke, 1984a), and help to rule out alternatives to the proposal that visual memories tend to undergo, at least to some extent, the transformations implied by a prior sequence of observed events.

  10. Collision-free motion coordination of heterogeneous robots

    International Nuclear Information System (INIS)

    Ko, Nak Yong; Seo, Dong Jin; Simmons, Reid G.

    2008-01-01

    This paper proposes a method to coordinate the motion of multiple heterogeneous robots on a network. The proposed method uses prioritization and avoidance. Priority is assigned to each robot; a robot with lower priority avoids the robots of higher priority. To avoid collision with other robots, elastic force and potential field force are used. Also, the method can be applied separately to the motion planning of a part of a robot from that of the other parts of the robot. This is useful for application to the robots of the type mobile manipulator or highly redundant robots. The method is tested by simulation, and it results in smooth and adaptive coordination in an environment with multiple heterogeneous robots

  11. Collision-free motion coordination of heterogeneous robots

    Energy Technology Data Exchange (ETDEWEB)

    Ko, Nak Yong [Chosun University, Gwangju (Korea, Republic of); Seo, Dong Jin [RedOne Technologies, Gwangju (Korea, Republic of); Simmons, Reid G. [Carnegie Mellon University, Pennsylvania (United States)

    2008-11-15

    This paper proposes a method to coordinate the motion of multiple heterogeneous robots on a network. The proposed method uses prioritization and avoidance. Priority is assigned to each robot; a robot with lower priority avoids the robots of higher priority. To avoid collision with other robots, elastic force and potential field force are used. Also, the method can be applied separately to the motion planning of a part of a robot from that of the other parts of the robot. This is useful for application to the robots of the type mobile manipulator or highly redundant robots. The method is tested by simulation, and it results in smooth and adaptive coordination in an environment with multiple heterogeneous robots

  12. Collision free pick up and movement of large objects

    International Nuclear Information System (INIS)

    Drotning, W.D.; McKee, G.R.

    1998-01-01

    An automated system is described for the sensor-based precision docking and manipulation of large objects. Past work in the remote handling of large nuclear waste containers is extensible to the problems associated with the handling of large objects such as coils of flat steel in industry. Computer vision and ultrasonic proximity sensing as described here are used to control the precision docking of large objects, and swing damped motion control of overhead cranes is used to control the position of the pick up device and suspended payload during movement. Real-time sensor processing and model-based control are used to accurately position payloads

  13. Relative sensory sparing in the diabetic foot implied through vibration testing

    Directory of Open Access Journals (Sweden)

    Todd O'Brien

    2013-09-01

    Full Text Available Background: The dorsal aspect of the hallux is often cited as the anatomic location of choice for vibration testing in the feet of diabetic patients. To validate this preference, vibration tests were performed and compared at the hallux and 5th metatarsal head in diabetic patients with established neuropathy. Methods: Twenty-eight neuropathic, diabetic patients and 17 non-neuropathic, non-diabetic patients underwent timed vibration testing (TVT with a novel 128 Hz electronic tuning fork (ETF at the hallux and 5th metatarsal head. Results: TVT values in the feet of diabetic patients were found to be reduced at both locations compared to controls. Unexpectedly, these values were significantly lower at the hallux (P < 0.001 compared to the 5th metatarsal head. Conclusion: This study confirms the hallux as the most appropriate location for vibration testing and implies relative sensory sparing at the 5th metatarsal head, a finding not previously reported in diabetic patients.

  14. [Discussion on ideological concept implied in traditional reinforcing and reducing method of acupuncture].

    Science.gov (United States)

    Li, Suyun; Zhao, Jingsheng

    2017-11-12

    The forming and development of traditional reinforcing and reducing method of acupuncture was rooted in traditional culture of China, and was based on the ancients' special understanding of nature, life and diseases, therefore its principle and methods were inevitably influenced by philosophy culture and medicine concept at that time. With deep study on Inner Canon of Huangdi and representative reinforcing and reducing method of acupuncture, the implied ideological concept, including contradiction view and profit-loss view in ancient dialectic, yin-yang balance theory, concept of life flow, monophyletic theory of qi , theory of existence of disease-evil, yin - yang astrology theory, theory of inter-promotion of five elements, were summarized and analyzed. The clarified and systematic understanding on guiding ideology of reinforcing and reducing method of acupuncture could significantly promote the understanding on principle, method, content and manipulation.

  15. The chain rule implies Tsirelson's bound: an approach from generalized mutual information

    International Nuclear Information System (INIS)

    Wakakuwa, Eyuri; Murao, Mio

    2012-01-01

    In order to analyze an information theoretical derivation of Tsirelson's bound based on information causality, we introduce a generalized mutual information (GMI), defined as the optimal coding rate of a channel with classical inputs and general probabilistic outputs. In the case where the outputs are quantum, the GMI coincides with the quantum mutual information. In general, the GMI does not necessarily satisfy the chain rule. We prove that Tsirelson's bound can be derived by imposing the chain rule on the GMI. We formulate a principle, which we call the no-supersignaling condition, which states that the assistance of nonlocal correlations does not increase the capability of classical communication. We prove that this condition is equivalent to the no-signaling condition. As a result, we show that Tsirelson's bound is implied by the nonpositivity of the quantitative difference between information causality and no-supersignaling. (paper)

  16. What the success of brain imaging implies about the neural code.

    Science.gov (United States)

    Guest, Olivia; Love, Bradley C

    2017-01-19

    The success of fMRI places constraints on the nature of the neural code. The fact that researchers can infer similarities between neural representations, despite fMRI's limitations, implies that certain neural coding schemes are more likely than others. For fMRI to succeed given its low temporal and spatial resolution, the neural code must be smooth at the voxel and functional level such that similar stimuli engender similar internal representations. Through proof and simulation, we determine which coding schemes are plausible given both fMRI's successes and its limitations in measuring neural activity. Deep neural network approaches, which have been forwarded as computational accounts of the ventral stream, are consistent with the success of fMRI, though functional smoothness breaks down in the later network layers. These results have implications for the nature of the neural code and ventral stream, as well as what can be successfully investigated with fMRI.

  17. The dynamic conditional relationship between stock market returns and implied volatility

    Science.gov (United States)

    Park, Sung Y.; Ryu, Doojin; Song, Jeongseok

    2017-09-01

    Using the dynamic conditional correlation multivariate generalized autoregressive conditional heteroskedasticity (DCC-MGARCH) model, we empirically examine the dynamic relationship between stock market returns (KOSPI200 returns) and implied volatility (VKOSPI), as well as their statistical mechanics, in the Korean market, a representative and leading emerging market. We consider four macroeconomic variables (exchange rates, risk-free rates, term spreads, and credit spreads) as potential determinants of the dynamic conditional correlation between returns and volatility. Of these macroeconomic variables, the change in exchange rates has a significant impact on the dynamic correlation between KOSPI200 returns and the VKOSPI, especially during the recent financial crisis. We also find that the risk-free rate has a marginal effect on this dynamic conditional relationship.

  18. Does a massive neutrino imply to go beyond the standard model?

    International Nuclear Information System (INIS)

    Le Diberder, F.; Cohen-Tannoudji, G.; Davier, M.

    2002-01-01

    This article gathers the 15 contributions to this seminar. The purpose of this seminar was to define up to which extend the standard model is challenged by massive neutrinos. A non-zero mass for neutrinos, even a few eV, would solve the problem of the missing mass of the universe, and it would mean no more need for supersymmetry and its neutralinos. A massless neutrino theoretically implies a symmetry and an interaction that are not described by the standard model. In some aspects, it appears that a non-zero mass is natural within the framework of the standard model, and for some scientists the smallness of this value could be the hint of the need for a new physics

  19. What implies the good work for registered nurses in municipal elderly care in Sweden?

    Science.gov (United States)

    Josefsson, Karin; Aling, Jenny; Östin, Britt-Louise

    2011-08-01

    The aim was to describe registered nurses' perceptions of what the good work implies to them in municipal elderly care. A descriptive design and a structured questionnaire specifically designed for this study were used. Sixty housing units for older people and 213 nurses participated, with a response rate of 62%. The good work included the following aspects: intellectually stimulating without guilt feelings; freedom and independence with the possibility to influence; having appreciative and pleasant fellow workers and a fair and understanding manager; a good physical and risk-free environment; work security and a steady income with the possibility of improving salary through work effort; work effort should be beneficial to others; innovative thinking and initiative should be highly valued; and pride in work without compromising personal values. Employers must take this into consideration to retain those nurses already employed and recruit nurses to municipal elderly care.

  20. Optimal Plant Carbon Allocation Implies a Biological Control on Nitrogen Availability

    Science.gov (United States)

    Prentice, I. C.; Stocker, B. D.

    2015-12-01

    The degree to which nitrogen availability limits the terrestrial C sink under rising CO2 is a key uncertainty in carbon cycle and climate change projections. Results from ecosystem manipulation studies and meta-analyses suggest that plant C allocation to roots adjusts dynamically under varying degrees of nitrogen availability and other soil fertility parameters. In addition, the ratio of biomass production to GPP appears to decline under nutrient scarcity. This reflects increasing plant C exudation into the soil (Cex) with decreasing nutrient availability. Cex is consumed by an array of soil organisms and may imply an improvement of nutrient availability to the plant. Thus, N availability is under biological control, but incurs a C cost. In spite of clear observational support, this concept is left unaccounted for in Earth system models. We develop a model for the coupled cycles of C and N in terrestrial ecosystems to explore optimal plant C allocation under rising CO2 and its implications for the ecosystem C balance. The model follows a balanced growth approach, accounting for the trade-offs between leaf versus root growth and Cex in balancing C fixation and N uptake. We assume that Cex is proportional to root mass, and that the ratio of N uptake (Nup) to Cex is proportional to inorganic N concentration in the soil solution. We further assume that Cex is consumed by N2-fixing processes if the ratio of Nup:Cex falls below the inverse of the C cost of N2-fixation. Our analysis thereby accounts for the feedbacks between ecosystem C and N cycling and stoichiometry. We address the question of how the plant C economy will adjust under rising atmospheric CO2 and what this implies for the ecosystem C balance and the degree of N limitation.

  1. Enacted and implied stigma for dementia in a community in south-west Nigeria.

    Science.gov (United States)

    Adebiyi, Akindele O; Fagbola, Motunrayo A; Olakehinde, Olaide; Ogunniyi, Adesola

    2016-07-01

    Dementia is a chronic progressive disease that mostly affects the elderly. There is often a stigma surrounding dementia patients because of poor awareness about the disease. In Nigeria, this stigma and related attitudes have not been fully explored. In this study, we assessed the attitude of people towards demented individuals in a transitional community in Nigeria. The study used a mixed methods approach. Focused group discussions exploring the concept of dementia were conducted among six community groups, and quantitative data was obtained from an interviewer-administered questionnaire. A total of 313 respondents were selected with a cluster sampling technique. Only 212 respondents (67.7%) were aware of dementia. 'Memory loss disease', 'ageing disease', 'disease of insanity', 'brain disorder', 'disease of forgetfulness', and 'dull brain' are the common names used to describe dementia in the community. Enacted stigma was evident as 36% of respondents felt dementia was associated with shame and embarrassment in the community. Implied stigma was evident in another third that opined that demented individuals would prefer not to know or let others know that they have the disease. Also, 28% were of the opinion that people do not take those with dementia seriously. Of the 22 (10.4%) that reported having received structured information about dementia, 16 (72.7%) got the information from health facilities. Qualitative data revealed the presence of enacted stigma in the community as some referred to affected individuals by derogatory names such as 'madman'. Some statements from the focus group discussion participants also gave useful insights into the scorn with which demented individuals are sometimes treated. The presence of enacted and implied stigma related to dementia within the community calls for concern. More research efforts are needed to unravel the burden of stigma within communities and best practice for stigma-reducing interventions. © 2015 The Authors

  2. Explaining the level of credit spreads: Option-implied jump risk premia in a firm value model

    NARCIS (Netherlands)

    Cremers, K.J.M.; Driessen, J.; Maenhout, P.

    2008-01-01

    We study whether option-implied jump risk premia can explain the high observed level of credit spreads. We use a structural jump-diffusion firm value model to assess the level of credit spreads generated by option-implied jump risk premia. Prices and returns of equity index and individual options

  3. 32 CFR 701.120 - Processing requests that cite or imply PA, Freedom of Information (FOIA), or PA/FOIA.

    Science.gov (United States)

    2010-07-01

    ... Privacy Program § 701.120 Processing requests that cite or imply PA, Freedom of Information (FOIA), or PA... maximum release of information allowed under the Acts. (d) Processing time limits. DON activities shall... 32 National Defense 5 2010-07-01 2010-07-01 false Processing requests that cite or imply PA...

  4. 78 FR 13665 - L.E. Bell Construction Company, Inc.; Notice of Termination of Exemption by Implied Surrender and...

    Science.gov (United States)

    2013-02-28

    ... Construction Company, Inc.; Notice of Termination of Exemption by Implied Surrender and Soliciting Comments... initiated by the Commission: a. Type of Proceeding: Termination of exemption by implied surrender. b... reserves the right to revoke an exemption if any term or condition of the exemption is violated. The...

  5. 76 FR 52657 - Herschel L. Webster; Revonda Amthor; Notice of Termination of Exemption by Implied Surrender and...

    Science.gov (United States)

    2011-08-23

    .... Webster; Revonda Amthor; Notice of Termination of Exemption by Implied Surrender and Soliciting Comments... initiated by the Commission: a. Type of Proceeding: Termination of exemption by implied surrender. b... exemption if any term or condition of the exemption is violated. The project has not operated since 1996 and...

  6. The role of implied motion in engaging audiences for health promotion: encouraging naps on a college campus.

    Science.gov (United States)

    Mackert, Michael; Lazard, Allison; Guadagno, Marie; Hughes Wagner, Jessica

    2014-01-01

    Lack of sleep among college students negatively impacts health and academic outcomes. Building on research that implied motion imagery increases brain activity, this project tested visual design strategies to increase viewers' engagement with a health communication campaign promoting napping to improve sleep habits. PARTICIPANTS (N = 194) were recruited from a large southwestern university in October 2012. Utilizing an experimental design, participants were assigned to 1 of 3 conditions: an implied motion superhero spokes-character, a static superhero spokes-character, and a control group. The use of implied motion did not achieve the hypothesized effect on message elaboration, but superheroes are a promising persuasive tool for health promotion campaigns for college audiences. Implications for sleep health promotion campaigns and the role of implied motion in message design strategies are discussed, as well as future directions for research on the depiction of implied motion as it relates to theoretical development.

  7. Exploring the assumed invariance of implied emission factors for forest biomass in greenhouse gas inventories

    International Nuclear Information System (INIS)

    Smith, James E.; Heath, Linda S.

    2010-01-01

    Reviews of each nation's annual greenhouse gas inventory submissions including forestland are part of the ongoing reporting process of the United Nations Framework Convention on Climate Change. Goals of these reviews include improving quality and consistency within and among reports. One method of facilitating comparisons is the use of a standard index such as an implied emission factor (IEF), which for forest biomass indicates net rate of carbon emission or sequestration per area. Guidance on the use of IEFs in reviews is limited, but there is an expectation that values should be relatively constant both over time and across spatial scales. To address this hypothesis, we examine IEFs over time, derived from U.S. forests at plot-, state-, and national-levels. Results show that at increasingly aggregated levels, relative heterogeneity decreases but can still be substantial. A net increase in U.S. whole-forest IEFs over time is consistent with results from temperate forests of nations in the European Community. IEFs are better viewed as a distribution of values rather than one constant value principally because of sensitivities to productivity, disturbance, and land use change, which can all vary considerably across a nation's forest land.

  8. Universal Property of Quantum Gravity implied by Bekenstein-Hawking Entropy and Boltzmann formula

    International Nuclear Information System (INIS)

    Saida, Hiromi

    2013-01-01

    We search for a universal property of quantum gravity. By u niversal , we mean the independence from any existing model of quantum gravity (such as the super string theory, loop quantum gravity, causal dynamical triangulation, and so on). To do so, we try to put the basis of our discussion on theories established by some experiments. Thus, we focus our attention on thermodynamical and statistical-mechanical basis of the black hole thermodynamics: Let us assume that the Bekenstein-Hawking entropy is given by the Boltzmann formula applied to the underlying theory of quantum gravity. Under this assumption, the conditions justifying Boltzmann formula together with uniqueness of Bekenstein-Hawking entropy imply a reasonable universal property of quantum gravity. The universal property indicates a repulsive gravity at Planck length scale, otherwise stationary black holes can not be regarded as thermal equilibrium states of gravity. Further, in semi-classical level, we discuss a possible correction of Einstein equation which generates repulsive gravity at Planck length scale.

  9. Large-scale subduction of continental crust implied by India-Asia mass-balance calculation

    Science.gov (United States)

    Ingalls, Miquela; Rowley, David B.; Currie, Brian; Colman, Albert S.

    2016-11-01

    Continental crust is buoyant compared with its oceanic counterpart and resists subduction into the mantle. When two continents collide, the mass balance for the continental crust is therefore assumed to be maintained. Here we use estimates of pre-collisional crustal thickness and convergence history derived from plate kinematic models to calculate the crustal mass balance in the India-Asia collisional system. Using the current best estimates for the timing of the diachronous onset of collision between India and Eurasia, we find that about 50% of the pre-collisional continental crustal mass cannot be accounted for in the crustal reservoir preserved at Earth's surface today--represented by the mass preserved in the thickened crust that makes up the Himalaya, Tibet and much of adjacent Asia, as well as southeast Asian tectonic escape and exported eroded sediments. This implies large-scale subduction of continental crust during the collision, with a mass equivalent to about 15% of the total oceanic crustal subduction flux since 56 million years ago. We suggest that similar contamination of the mantle by direct input of radiogenic continental crustal materials during past continent-continent collisions is reflected in some ocean crust and ocean island basalt geochemistry. The subduction of continental crust may therefore contribute significantly to the evolution of mantle geochemistry.

  10. Market-implied spread for earthquake CAT bonds: financial implications of engineering decisions.

    Science.gov (United States)

    Damnjanovic, Ivan; Aslan, Zafer; Mander, John

    2010-12-01

    In the event of natural and man-made disasters, owners of large-scale infrastructure facilities (assets) need contingency plans to effectively restore the operations within the acceptable timescales. Traditionally, the insurance sector provides the coverage against potential losses. However, there are many problems associated with this traditional approach to risk transfer including counterparty risk and litigation. Recently, a number of innovative risk mitigation methods, termed alternative risk transfer (ART) methods, have been introduced to address these problems. One of the most important ART methods is catastrophe (CAT) bonds. The objective of this article is to develop an integrative model that links engineering design parameters with financial indicators including spread and bond rating. The developed framework is based on a four-step structural loss model and transformed survival model to determine expected excess returns. We illustrate the framework for a seismically designed bridge using two unique CAT bond contracts. The results show a nonlinear relationship between engineering design parameters and market-implied spread. © 2010 Society for Risk Analysis.

  11. Analysis of model implied volatility for jump diffusion models: Empirical evidence from the Nordpool market

    International Nuclear Information System (INIS)

    Nomikos, Nikos K.; Soldatos, Orestes A.

    2010-01-01

    In this paper we examine the importance of mean reversion and spikes in the stochastic behaviour of the underlying asset when pricing options on power. We propose a model that is flexible in its formulation and captures the stylized features of power prices in a parsimonious way. The main feature of the model is that it incorporates two different speeds of mean reversion to capture the differences in price behaviour between normal and spiky periods. We derive semi-closed form solutions for European option prices using transform analysis and then examine the properties of the implied volatilities that the model generates. We find that the presence of jumps generates prominent volatility skews which depend on the sign of the mean jump size. We also show that mean reversion reduces the volatility smile as time to maturity increases. In addition, mean reversion induces volatility skews particularly for ITM options, even in the absence of jumps. Finally, jump size volatility and jump intensity mainly affect the kurtosis and thus the curvature of the smile with the former having a more important role in making the volatility smile more pronounced and thus increasing the kurtosis of the underlying price distribution.

  12. Low Seismic Attenuation in Southern New England Lithosphere Implies Little Heating by the Upwelling Asthenosphere

    Science.gov (United States)

    Lamoureux, J. M.; Menke, W. H.

    2017-12-01

    The Northern Appalachian Anomaly (NAA) is a patch of the asthenosphere in southern New England that is unusually hot given its passive margin setting. Previous research has detected large seismic wave delays that imply a temperature of 770 deg C higher than the mantle below the adjacent craton at the same depth. A key outstanding issue is whether the NAA interacts with the lithosphere above it (e.g. by heating it up). We study this issue using Po and So waves from two magnitude >5.5 earthquakes near the Puerto Rico Trench. These waves, propagating in the cold oceanic lithosphere at near Moho speeds, deliver high frequency energy to the shallow continental lithosphere. We hypothesized that: (1) once within the continental lithosphere, Po and So experience attenuation with distance that can be quantified by a quality factor Q, and that (2) any heating of the lithosphere above the NAA would lead to a higher Q than in regions further north or south along the continental margin. Corresponding Po and So velocities would also be lower. The decay rates of Po and So are estimated using least-squares applied to RMS coda amplitudes measured from digital seismograms from stations in northeastern North America, corrected for instrument response. A roughly log-linear decrease in amplitude is observed, corresponding to P and S wave quality factors in the range of 394-1500 and 727-6847, respectively. Measurements are made for four margin-perpendicular geographical bands, with one band overlapping the NAA. We detect no effect on these amplitudes by the NAA; 95% confidence bounds overlap in every case; Furthermore, all quality factors are much higher than the 100 predicted by lab experiments for near-solidus mantle rocks. These results suggest that the NAA is not causing significant heating of the lithosphere above it. The shear velocities, however, are about 10% slower above the NAA - an effect that may be fossil, reflecting processes that occurred millions of years ago.

  13. Microstructures imply cataclasis and authigenic mineral formation control geomechanical properties of New Zealand's Alpine Fault

    Science.gov (United States)

    Schuck, B.; Janssen, C.; Schleicher, A. M.; Toy, V. G.; Dresen, G.

    2018-05-01

    The Alpine Fault is capable of generating large (MW > 8) earthquakes and is the main geohazard on South Island, NZ, and late in its 250-291-year seismic cycle. To minimize its hazard potential, it is indispensable to identify and understand the processes influencing the geomechanical behavior and strength-evolution of the fault. High-resolution microstructural, mineralogical and geochemical analyses of the Alpine Fault's core demonstrate wall rock fragmentation, assisted by mineral dissolution, and cementation resulting in the formation of a fine-grained principal slip zone (PSZ). A complex network of anastomosing and mutually cross-cutting calcite veins implies that faulting occurred during episodes of dilation, slip and sealing. Fluid-assisted dilatancy leads to a significant volume increase accommodated by vein formation in the fault core. Undeformed euhedral chlorite crystals and calcite veins that have cut footwall gravels demonstrate that these processes occurred very close to the Earth's surface. Microstructural evidence indicates that cataclastic processes dominate the deformation and we suggest that powder lubrication and grain rolling, particularly influenced by abundant nanoparticles, play a key role in the fault core's velocity-weakening behavior rather than frictional sliding. This is further supported by the absence of smectite, which is reasonable given recently measured geothermal gradients of more than 120 °C km-1 and the impermeable nature of the PSZ, which both limit the growth of this phase and restrict its stability to shallow depths. Our observations demonstrate that high-temperature fluids can influence authigenic mineral formation and thus control the fault's geomechanical behavior and the cyclic evolution of its strength.

  14. Quantifying differences in land use emission estimates implied by definition discrepancies

    Science.gov (United States)

    Stocker, B. D.; Joos, F.

    2015-11-01

    The quantification of CO2 emissions from anthropogenic land use and land use change (eLUC) is essential to understand the drivers of the atmospheric CO2 increase and to inform climate change mitigation policy. Reported values in synthesis reports are commonly derived from different approaches (observation-driven bookkeeping and process-modelling) but recent work has emphasized that inconsistencies between methods may imply substantial differences in eLUC estimates. However, a consistent quantification is lacking and no concise modelling protocol for the separation of primary and secondary components of eLUC has been established. Here, we review differences of eLUC quantification methods and apply an Earth System Model (ESM) of Intermediate Complexity to quantify them. We find that the magnitude of effects due to merely conceptual differences between ESM and offline vegetation model-based quantifications is ~ 20 % for today. Under a future business-as-usual scenario, differences tend to increase further due to slowing land conversion rates and an increasing impact of altered environmental conditions on land-atmosphere fluxes. We establish how coupled Earth System Models may be applied to separate secondary component fluxes of eLUC arising from the replacement of potential C sinks/sources and the land use feedback and show that secondary fluxes derived from offline vegetation models are conceptually and quantitatively not identical to either, nor their sum. Therefore, we argue that synthesis studies should resort to the "least common denominator" of different methods, following the bookkeeping approach where only primary land use emissions are quantified under the assumption of constant environmental boundary conditions.

  15. Large differences in land use emission quantifications implied by definition discrepancies

    Science.gov (United States)

    Stocker, B. D.; Joos, F.

    2015-03-01

    The quantification of CO2 emissions from anthropogenic land use and land use change (eLUC) is essential to understand the drivers of the atmospheric CO2 increase and to inform climate change mitigation policy. Reported values in synthesis reports are commonly derived from different approaches (observation-driven bookkeeping and process-modelling) but recent work has emphasized that inconsistencies between methods may imply substantial differences in eLUC estimates. However, a consistent quantification is lacking and no concise modelling protocol for the separation of primary and secondary components of eLUC has been established. Here, we review the conceptual differences of eLUC quantification methods and apply an Earth System Model to demonstrate that what is claimed to represent total eLUC differs by up to ~20% when quantified from ESM vs. offline vegetation models. Under a future business-as-usual scenario, differences tend to increase further due to slowing land conversion rates and an increasing impact of altered environmental conditions on land-atmosphere fluxes. We establish how coupled Earth System Models may be applied to separate component fluxes of eLUC arising from the replacement of potential C sinks/sources and the land use feedback and show that secondary fluxes derived from offline vegetation models are conceptually and quantitatively not identical to either, nor their sum. Therefore, we argue that synthesis studies and global carbon budget accountings should resort to the "least common denominator" of different methods, following the bookkeeping approach where only primary land use emissions are quantified under the assumption of constant environmental boundary conditions.

  16. Object Localization Does Not Imply Awareness of Object Category at the Break of Continuous Flash Suppression

    Directory of Open Access Journals (Sweden)

    Florian Kobylka

    2017-06-01

    Full Text Available In continuous flash suppression (CFS, a dynamic noise masker, presented to one eye, suppresses conscious perception of a test stimulus, presented to the other eye, until the suppressed stimulus comes to awareness after few seconds. But what do we see breaking the dominance of the masker in the transition period? We addressed this question with a dual-task in which observers indicated (i whether the test object was left or right of the fixation mark (localization and (ii whether it was a face or a house (categorization. As done recently Stein et al. (2011a, we used two experimental varieties to rule out confounds with decisional strategy. In the terminated mode, stimulus and masker were presented for distinct durations, and the observers were asked to give both judgments at the end of the trial. In the self-paced mode, presentation lasted until the observers responded. In the self-paced mode, b-CFS durations for object categorization were about half a second longer than for object localization. In the terminated mode, correct categorization rates were consistently lower than correct detection rates, measured at five duration intervals ranging up to 2 s. In both experiments we observed an upright face advantage compared to inverted faces and houses, as concurrently reported in b-CFS studies. Our findings reveal that more time is necessary to enable observers judging the nature of the object, compared to judging that there is “something other” than the noise which can be localized, but not recognized. This suggests gradual transitions in the first break of CFS. Further, the results imply that suppression is such that no cues to object identity are conveyed in potential “leaks” of CFS (Gelbard-Sagiv et al., 2016.

  17. 16 CFR 303.40 - Use of terms in written advertisements that imply presence of a fiber.

    Science.gov (United States)

    2010-01-01

    ... 16 Commercial Practices 1 2010-01-01 2010-01-01 false Use of terms in written advertisements that imply presence of a fiber. 303.40 Section 303.40 Commercial Practices FEDERAL TRADE COMMISSION REGULATIONS UNDER SPECIFIC ACTS OF CONGRESS RULES AND REGULATIONS UNDER THE TEXTILE FIBER PRODUCTS IDENTIFICATION ACT § 303.40 Use of terms in written...

  18. The Role of Implied Volatility in Forecasting Future Realized Volatility and Jumps in Foreign Exchange, Stock and Bond Markets

    DEFF Research Database (Denmark)

    Christensen, Bent Jesper

    We study the forecasting of future realized volatility in the stock, bond, and foreign exchange markets, as well as the continuous sample path and jump components of this, from variables in the information set, including implied volatility backed out from option prices. Recent nonparametric...

  19. The Role of Implied Motion in Engaging Audiences for Health Promotion: Encouraging Naps on a College Campus

    Science.gov (United States)

    Mackert, Michael; Lazard, Allison; Guadagno, Marie; Hughes Wagner, Jessica

    2014-01-01

    Objective: Lack of sleep among college students negatively impacts health and academic outcomes. Building on research that implied motion imagery increases brain activity, this project tested visual design strategies to increase viewers' engagement with a health communication campaign promoting napping to improve sleep habits. Participants:…

  20. Dynamic Estimation of Volatility Risk Premia and Investor Risk Aversion from Option-Implied and Realized Volatilities

    DEFF Research Database (Denmark)

    Bollerslev, Tim; Gibson, Michael; Zhou, Hao

    experiment confirms that the procedure works well in practice. Implementing the procedure with actual S&P500 option-implied volatilities and high-frequency five-minute-based realized volatilities indicates significant temporal dependencies in the estimated stochastic volatility risk premium, which we in turn...

  1. 75 FR 16099 - Mr. Jerry McMillan and Ms. Christine Smith; Notice of Termination of License by Implied Surrender...

    Science.gov (United States)

    2010-03-31

    ... McMillan and Ms. Christine Smith; Notice of Termination of License by Implied Surrender and Soliciting... surrender b. Project No.: P-9907-018 c. Licensees: Mr. Jerry McMillan and Ms. Christine Smith d. Name of... ] 62,282). The project was transferred to Mr. Jerry McMillan and Ms. Christine Smith by order on...

  2. On a problematic procedure to manipulate response biases in recognition experiments: the case of "implied" base rates.

    Science.gov (United States)

    Bröder, Arndt; Malejka, Simone

    2017-07-01

    The experimental manipulation of response biases in recognition-memory tests is an important means for testing recognition models and for estimating their parameters. The textbook manipulations for binary-response formats either vary the payoff scheme or the base rate of targets in the recognition test, with the latter being the more frequently applied procedure. However, some published studies reverted to implying different base rates by instruction rather than actually changing them. Aside from unnecessarily deceiving participants, this procedure may lead to cognitive conflicts that prompt response strategies unknown to the experimenter. To test our objection, implied base rates were compared to actual base rates in a recognition experiment followed by a post-experimental interview to assess participants' response strategies. The behavioural data show that recognition-memory performance was estimated to be lower in the implied base-rate condition. The interview data demonstrate that participants used various second-order response strategies that jeopardise the interpretability of the recognition data. We thus advice researchers against substituting actual base rates with implied base rates.

  3. Hydrodynamic Delivery of Cre Protein to Lineage-Mark or Time-Stamp Mouse Hepatocytes In situ

    Science.gov (United States)

    Sonsteng, Katherine M.; Prigge, Justin R.; Talago, Emily A.; June, Ronald K.; Schmidt, Edward E.

    2014-01-01

    Cre-responsive fluorescent marker alleles are powerful tools for cell lineage tracing in mice; however their utility is limited by regulation of Cre activity. When targeting hepatocytes, hydrodynamic delivery of a Cre-expression plasmid can convert Cre-responsive alleles without inducing the intracellular or systemic antiviral responses often associated with viral-derived Cre-expression vectors. In this method, rapid high-volume intravenous inoculation induces hepatocyte-targeted uptake of extracellular molecules. Here we tested whether hydrodynamic delivery of Cre protein or Cre fused to the HIV-TAT cell-penetrating peptide could convert Cre-responsive reporters in hepatocytes of mice. Hydrodynamic delivery of 2 nmol of either Cre or TAT-Cre protein converted the reporter allele in 5 to 20% of hepatocytes. Neither protein gave detectable Cre activity in endothelia, non-liver organs, or non-hepatocyte cells in liver. Using mice homozygous for a Cre-responsive marker that directs red- (Cre-naïve) or green- (Cre-converted) fluorescent proteins to the nucleus, we assessed sub-saturation Cre-activity. One month after hydrodynamic inoculation with Cre protein, 58% of hepatocyte nuclei that were green were also red, indicating that less than half of the hepatocytes that had obtained enough Cre to convert one marker allele to green were able to convert all alleles. For comparison, one month after hydrodynamic delivery of a Cre-expression plasmid with a weak promoter, only 26% of the green nuclei were also red. Our results show that hydrodynamic delivery of Cre protein allows rapid allelic conversion in hepatocytes, but Cre-activity is sub-saturating so many cells will not convert multiple Cre-responsive alleles. PMID:24626158

  4. Fast Data Acquisition system based on NI-myRIO board with GPS time stamping capabilities for atmospheric electricity research

    International Nuclear Information System (INIS)

    Pokhsraryan, D.

    2016-01-01

    In the investigation of the fast physical processes, such as propagation of a lightning leader and detection of the correspondent radio emission waveforms, it is crucial to synchronize the corresponding signals in order to be able to create a model of the lightning initiation. Therefore, the DAQ system should be equipped with a GPS synchronization capability. In the presented report, we describe the DAQ system based on a NI-myRio board that provides detection of particle fluxes, the near-surface electric field disturbances and waveforms of radio signals from atmospheric discharges, all synchronized with an accuracy of tens of nanoseconds. The results of the first measurements made at Aragats high-altitude station of Yerevan Physics Institute in Summer-Autumn 2015 are presented and discussed. (author)

  5. Revisiting the long memory dynamics of the implied-realized volatility relationship: New evidence from the wavelet regression

    Czech Academy of Sciences Publication Activity Database

    Baruník, Jozef; Hlínková, M.

    2016-01-01

    Roč. 54, č. 1 (2016), s. 503-514 ISSN 0264-9993 R&D Projects: GA ČR(CZ) GBP402/12/G097 Institutional support: RVO:67985556 Keywords : wavelet band spectrum regression * corridor implied volatility * realized volatility * fractional cointegration Subject RIV: AH - Economics Impact factor: 1.481, year: 2016 http://library.utia.cas.cz/separaty/2016/E/barunik-0456186.pdf

  6. The information content of implied volatilities of options on eurodeposit futures traded on the LIFFE: is there long memory?

    OpenAIRE

    Cifarelli, giulio

    2002-01-01

    Under rather general conditions Black - Scholes implied volatilities from at-the-money options appropriately quantify, in each period, the market expectations of the average volatility of the return of the underlying asset until contract expiration. The efficiency of these expectation estimates is investigated here, for options on two major short term interest rate futures contracts traded at the LIFFE, using a long memory framework. Over the 1993 – 1997 time interval the performance of im...

  7. Forecasting Daily Variability of the S and P 100 Stock Index using Historical, Realised and Implied Volatility Measurements

    OpenAIRE

    Koopman, Siem Jan; Jungbacker, Borus; Hol, Eugenie

    2004-01-01

    The increasing availability of financial market data at intraday frequencies has not only led to the development of improved volatility measurements but has also inspired research into their potential value as an information source for volatility forecasting. In this paper we explore the forecasting value of historical volatility (extracted from daily return series), of implied volatility (extracted from option pricing data) and of realised volatility (computed as the sum of squared high freq...

  8. Forecasting the density of oil futures returns using model-free implied volatility and high-frequency data

    International Nuclear Information System (INIS)

    Ielpo, Florian; Sevi, Benoit

    2013-09-01

    Forecasting the density of returns is useful for many purposes in finance, such as risk management activities, portfolio choice or derivative security pricing. Existing methods to forecast the density of returns either use prices of the asset of interest or option prices on this same asset. The latter method needs to convert the risk-neutral estimate of the density into a physical measure, which is computationally cumbersome. In this paper, we take the view of a practitioner who observes the implied volatility under the form of an index, namely the recent OVX, to forecast the density of oil futures returns for horizons going from 1 to 60 days. Using the recent methodology in Maheu and McCurdy (2011) to compute density predictions, we compare the performance of time series models using implied volatility and either daily or intra-daily futures prices. Our results indicate that models based on implied volatility deliver significantly better density forecasts at all horizons, which is in line with numerous studies delivering the same evidence for volatility point forecast. (authors)

  9. Drought-breaking love: An analysis of the moral values implied in ‘Drought’ by Jan Rabie

    OpenAIRE

    C. N. van der Merwe

    1996-01-01

    In this article the tension in 20th century literary theory between absolutism and relativism is discussed. It is argued that, in spite of a movement from absolutism towards relativism, the age-old “absolute” values of truth, beauty and goodness have never been totally forsaken in the creation and the contemplation of literature. In an analysis of “Drought” by Jan Rabie, it is indicated how these values are implied and invoked in Rabie's short story. In conclusion, the fundamental value of lo...

  10. The implied volatility of index options: the evidence of options on the Australian SPI 200 index futures

    OpenAIRE

    Tanha, Hassan

    2017-01-01

    This thesis is a study of the implied volatility component of the Black and Scholes option-pricing model. A recurring finding in the thesis is that in-the-money and out-of ¬the-money options should not be regarded as being on a continuum, but rather as being inherently "different." Additionally, differences across these options are accounted for in relation to behavioural and consumption based models, which, in turn, provide an explanation for the volatility smile. These findings provide a re...

  11. A numerical method to estimate the parameters of the CEV model implied by American option prices: Evidence from NYSE

    International Nuclear Information System (INIS)

    Ballestra, Luca Vincenzo; Cecere, Liliana

    2016-01-01

    Highlights: • We develop a method to compute the parameters of the CEV model implied by American options. • This is the first procedure for calibrating the CEV model to American option prices. • The proposed approach is extensively tested on the NYSE market. • The novel method turns out to be very efficient in computing the CEV model parameters. • The CEV model provides only a marginal improvement over the lognormal model. - Abstract: We develop a highly efficient procedure to forecast the parameters of the constant elasticity of variance (CEV) model implied by American options. In particular, first of all, the American option prices predicted by the CEV model are calculated using an accurate and fast finite difference scheme. Then, the parameters of the CEV model are obtained by minimizing the distance between theoretical and empirical option prices, which yields an optimization problem that is solved using an ad-hoc numerical procedure. The proposed approach, which turns out to be very efficient from the computational standpoint, is used to test the goodness-of-fit of the CEV model in predicting the prices of American options traded on the NYSE. The results obtained reveal that the CEV model does not provide a very good agreement with real market data and yields only a marginal improvement over the more popular Black–Scholes model.

  12. Drought-breaking love: An analysis of the moral values implied in ‘Drought’ by Jan Rabie

    Directory of Open Access Journals (Sweden)

    C. N. van der Merwe

    1996-04-01

    Full Text Available In this article the tension in 20th century literary theory between absolutism and relativism is discussed. It is argued that, in spite of a movement from absolutism towards relativism, the age-old “absolute” values of truth, beauty and goodness have never been totally forsaken in the creation and the contemplation of literature. In an analysis of “Drought” by Jan Rabie, it is indicated how these values are implied and invoked in Rabie's short story. In conclusion, the fundamental value of love or charity is discussed, a value which contains and supersedes the values of truth, beauty and goodness, and reconciles the tension between absolutism and relativism.

  13. Packaging signals in two single-stranded RNA viruses imply a conserved assembly mechanism and geometry of the packaged genome.

    Science.gov (United States)

    Dykeman, Eric C; Stockley, Peter G; Twarock, Reidun

    2013-09-09

    The current paradigm for assembly of single-stranded RNA viruses is based on a mechanism involving non-sequence-specific packaging of genomic RNA driven by electrostatic interactions. Recent experiments, however, provide compelling evidence for sequence specificity in this process both in vitro and in vivo. The existence of multiple RNA packaging signals (PSs) within viral genomes has been proposed, which facilitates assembly by binding coat proteins in such a way that they promote the protein-protein contacts needed to build the capsid. The binding energy from these interactions enables the confinement or compaction of the genomic RNAs. Identifying the nature of such PSs is crucial for a full understanding of assembly, which is an as yet untapped potential drug target for this important class of pathogens. Here, for two related bacterial viruses, we determine the sequences and locations of their PSs using Hamiltonian paths, a concept from graph theory, in combination with bioinformatics and structural studies. Their PSs have a common secondary structure motif but distinct consensus sequences and positions within the respective genomes. Despite these differences, the distributions of PSs in both viruses imply defined conformations for the packaged RNA genomes in contact with the protein shell in the capsid, consistent with a recent asymmetric structure determination of the MS2 virion. The PS distributions identified moreover imply a preferred, evolutionarily conserved assembly pathway with respect to the RNA sequence with potentially profound implications for other single-stranded RNA viruses known to have RNA PSs, including many animal and human pathogens. Copyright © 2013 Elsevier Ltd. All rights reserved.

  14. Estimating the implied cost of carbon in future scenarios using a CGE model: The Case of Colorado

    International Nuclear Information System (INIS)

    Hannum, Christopher; Cutler, Harvey; Iverson, Terrence; Keyser, David

    2017-01-01

    Using Colorado as a case study, we develop a state-level computable general equilibrium (CGE) model that reflects the roles of coal, natural gas, wind, solar, and hydroelectricity in supplying electricity. We focus on the economic impact of implementing Colorado's existing Renewable Portfolio Standard, updated in 2013. This requires that 25% of state generation come from qualifying renewable sources by 2020. We evaluate the policy under a variety of assumptions regarding wind integration costs and assumptions on the persistence of federal subsidies for wind. Specifically, we estimate the implied price of carbon as the carbon price at which a state-level policy would pass a state-level cost-benefit analysis, taking account of estimated greenhouse gas emission reductions and ancillary benefits from corresponding reductions in criteria pollutants. Our findings suggest that without the Production Tax Credit (federal aid), the state policy of mandating renewable power generation (RPS) is costly to state actors, with an implied cost of carbon of about $17 per ton of CO2 with a 3% discount rate. Federal aid makes the decision between natural gas and wind nearly cost neutral for Colorado. - Highlights: • If variability cost is low and renewables are federally subsidized, RPS is beneficial. • With no PTC or high variability cost, drop in real consumption less than 0.1%. • With PTC phaseout and high variability cost ICP is low, between $7.16 and $11.45. • With no PTC and high variability cost ICP is between $12.66 and $17.34 per ton.

  15. Implied motion because of instability in Hokusai Manga activates the human motion-sensitive extrastriate visual cortex: an fMRI study of the impact of visual art.

    Science.gov (United States)

    Osaka, Naoyuki; Matsuyoshi, Daisuke; Ikeda, Takashi; Osaka, Mariko

    2010-03-10

    The recent development of cognitive neuroscience has invited inference about the neurosensory events underlying the experience of visual arts involving implied motion. We report functional magnetic resonance imaging study demonstrating activation of the human extrastriate motion-sensitive cortex by static images showing implied motion because of instability. We used static line-drawing cartoons of humans by Hokusai Katsushika (called 'Hokusai Manga'), an outstanding Japanese cartoonist as well as famous Ukiyoe artist. We found 'Hokusai Manga' with implied motion by depicting human bodies that are engaged in challenging tonic posture significantly activated the motion-sensitive visual cortex including MT+ in the human extrastriate cortex, while an illustration that does not imply motion, for either humans or objects, did not activate these areas under the same tasks. We conclude that motion-sensitive extrastriate cortex would be a critical region for perception of implied motion in instability.

  16. Health Complaints Associated with Poor Rental Housing Conditions in Arkansas: The Only State without a Landlord's Implied Warranty of Habitability.

    Science.gov (United States)

    Bachelder, Ashley E; Stewart, M Kate; Felix, Holly C; Sealy, Neil

    2016-01-01

    Arkansas is the only U.S. state that does not have a landlord's implied warranty of habitability, meaning tenants have a requirement for maintaining their rental properties at certain habitability standards, but landlords are not legally required to contribute to those minimum health and safety standards. This project assessed the possibility that this lack of landlord responsibility affects tenants' perceived health. Using surveys and interviews, we collected self-reported data on the prevalence and description of problems faced by renters who needed household repairs from their landlords. Of almost 1,000 renters, one-third of them had experienced a problem with their landlord making needed repairs; and one-quarter of those had a health issue they attributed to their housing conditions. Common issues included problems with plumbing, heating, or cooling systems, and pest or rodent control. Reported health problems included elevated stress levels, breathing problems, headaches, high blood pressure, and bites or infections. Hispanic respondents and those with less than a high school education were both significantly more likely to report problems with their landlords not making repairs as requested. These data suggest that the lack of landlord requirements may negatively impact the condition of rental properties and, therefore, may negatively impact the health of Arkansas renters.

  17. Spatially robust estimates of biological nitrogen (N) fixation imply substantial human alteration of the tropical N cycle.

    Science.gov (United States)

    Sullivan, Benjamin W; Smith, W Kolby; Townsend, Alan R; Nasto, Megan K; Reed, Sasha C; Chazdon, Robin L; Cleveland, Cory C

    2014-06-03

    Biological nitrogen fixation (BNF) is the largest natural source of exogenous nitrogen (N) to unmanaged ecosystems and also the primary baseline against which anthropogenic changes to the N cycle are measured. Rates of BNF in tropical rainforest are thought to be among the highest on Earth, but they are notoriously difficult to quantify and are based on little empirical data. We adapted a sampling strategy from community ecology to generate spatial estimates of symbiotic and free-living BNF in secondary and primary forest sites that span a typical range of tropical forest legume abundance. Although total BNF was higher in secondary than primary forest, overall rates were roughly five times lower than previous estimates for the tropical forest biome. We found strong correlations between symbiotic BNF and legume abundance, but we also show that spatially free-living BNF often exceeds symbiotic inputs. Our results suggest that BNF in tropical forest has been overestimated, and our data are consistent with a recent top-down estimate of global BNF that implied but did not measure low tropical BNF rates. Finally, comparing tropical BNF within the historical area of tropical rainforest with current anthropogenic N inputs indicates that humans have already at least doubled reactive N inputs to the tropical forest biome, a far greater change than previously thought. Because N inputs are increasing faster in the tropics than anywhere on Earth, both the proportion and the effects of human N enrichment are likely to grow in the future.

  18. Spatially robust estimates of biological nitrogen (N) fixation imply substantial human alteration of the tropical N cycle

    Science.gov (United States)

    Sullivan, Benjamin W.; Smith, William K.; Townsend, Alan R.; Nasto, Megan K.; Reed, Sasha C.; Chazdon, Robin L.; Cleveland, Cory C.

    2014-01-01

    Biological nitrogen fixation (BNF) is the largest natural source of exogenous nitrogen (N) to unmanaged ecosystems and also the primary baseline against which anthropogenic changes to the N cycle are measured. Rates of BNF in tropical rainforest are thought to be among the highest on Earth, but they are notoriously difficult to quantify and are based on little empirical data. We adapted a sampling strategy from community ecology to generate spatial estimates of symbiotic and free-living BNF in secondary and primary forest sites that span a typical range of tropical forest legume abundance. Although total BNF was higher in secondary than primary forest, overall rates were roughly five times lower than previous estimates for the tropical forest biome. We found strong correlations between symbiotic BNF and legume abundance, but we also show that spatially free-living BNF often exceeds symbiotic inputs. Our results suggest that BNF in tropical forest has been overestimated, and our data are consistent with a recent top-down estimate of global BNF that implied but did not measure low tropical BNF rates. Finally, comparing tropical BNF within the historical area of tropical rainforest with current anthropogenic N inputs indicates that humans have already at least doubled reactive N inputs to the tropical forest biome, a far greater change than previously thought. Because N inputs are increasing faster in the tropics than anywhere on Earth, both the proportion and the effects of human N enrichment are likely to grow in the future.

  19. Linkages among U.S. Treasury Bond Yields, Commodity Futures and Stock Market Implied Volatility: New Nonparametric Evidence

    Directory of Open Access Journals (Sweden)

    Vychytilova Jana

    2015-09-01

    Full Text Available This paper aims to explore specific cross-asset market correlations over the past fifteen- yearperiod-from January 04, 1999 till April 01, 2015, and within four sub-phases covering both the crisis and the non-crisis periods. On the basis of multivariate statistical methods, we focus on investigating relations between selected well-known market indices- U.S. treasury bond yields- the 30-year treasury yield index (TYX and the 10-year treasury yield (TNX; commodity futures the TR/J CRB; and implied volatility of S&P 500 index- the VIX. We estimate relative logarithmic returns by using monthly close prices adjusted for dividends and splits and run normality and correlation analyses. This paper indicates that the TR/J CRB can be adequately modeled by a normal distribution, whereas the rest of benchmarks do not come from a normal distribution. This paper, inter alia, points out some evidence of a statistically significant negative relationship between bond yields and the VIX in the past fifteen years and a statistically significant negative linkage between the TR/J CRB and the VIX since 2009. In rather general terms, this paper thereafter supports the a priori idea- financial markets are interconnected. Such knowledge can be beneficial for building and testing accurate financial market models, and particularly for the understanding and recognizing market cycles.

  20. Corporate Moral Duties: Consequentialism, Collective Moral Agency and the “Ought” Implies “Can” Maxim

    Directory of Open Access Journals (Sweden)

    Leandro Martins Zanitelli

    2013-12-01

    Full Text Available The claim according to which corporations are morally responsible is a controversial one. At the same time, it is nowadays common to assign moral duties to companies, especially in work confronting the business and human rights issue. Can companies bear moral duties without being morally responsible? This article presents three different accounts of the duty to follow the course of action with the best consequences (consequentialist duty. The ascription of that duty to business is compatible with the claim that, by not being volitional agents, companies are not morally responsible for anything they do. The paper also addresses two possible objections against the claim that companies bear the duty of taking the course of action with the best consequences. These objections state that corporations are incapable of acting, be it in a general way (i.e. corporations do not possess the moral status of agents, be it regarding particular acts (the objection grounded on the “ought” implies “can” maxim.

  1. Motor facilitation during observation of implied motion: Evidence for a role of the left dorsolateral prefrontal cortex.

    Science.gov (United States)

    Mineo, Ludovico; Fetterman, Alexander; Concerto, Carmen; Warren, Michael; Infortuna, Carmenrita; Freedberg, David; Chusid, Eileen; Aguglia, Eugenio; Battaglia, Fortunato

    2018-06-01

    The phenomenon of motor resonance (the increase in motor cortex excitability during observation of actions) has been previously described. Transcranial magnetic stimulation (TMS) studies have demonstrated a similar effect during perception of implied motion (IM). The left dorsolateral prefrontal cortex (DLPFC) seems to be activated during action observation. Furthermore, the role of this brain area in motor resonance to IM is yet to be investigated. Fourteen healthy volunteers were enrolled into the study. We used transcranial direct current stimulation (tDCS) to stimulate DLPFC aiming to investigate whether stimulation with different polarities would affect the amplitude of motor evoked potential collected during observation of images with and without IM. The results of our experiment indicated that Cathodal tDCS over the left DLPFC prevented motor resonance during observation of IM. On the contrary, anodal and sham tDCS did not significantly modulate motor resonance to IM. The current study expands the understanding of the neural circuits engaged during observation of IM. Our results are consistent with the hypothesis that action understanding requires the interaction of large networks and that the left DLPFC plays a crucial role in generating motor resonance to IM. Copyright © 2018 Elsevier B.V. All rights reserved.

  2. Cone photoreceptor sensitivities and unique hue chromatic responses: correlation and causation imply the physiological basis of unique hues.

    Directory of Open Access Journals (Sweden)

    Ralph W Pridmore

    Full Text Available This paper relates major functions at the start and end of the color vision process. The process starts with three cone photoreceptors transducing light into electrical responses. Cone sensitivities were once expected to be Red Green Blue color matching functions (to mix colors but microspectrometry proved otherwise: they instead peak in yellowish, greenish, and blueish hues. These physiological functions are an enigma, unmatched with any set of psychophysical (behavioral functions. The end-result of the visual process is color sensation, whose essential percepts are unique (or pure hues red, yellow, green, blue. Unique hues cannot be described by other hues, but can describe all other hues, e.g., that hue is reddish-blue. They are carried by four opponent chromatic response curves but the literature does not specify whether each curve represents a range of hues or only one hue (a unique over its wavelength range. Here the latter is demonstrated, confirming that opponent chromatic responses define, and may be termed, unique hue chromatic responses. These psychophysical functions also are an enigma, unmatched with any physiological functions or basis. Here both enigmas are solved by demonstrating the three cone sensitivity curves and the three spectral chromatic response curves are almost identical sets (Pearson correlation coefficients r from 0.95-1.0 in peak wavelengths, curve shapes, math functions, and curve crossover wavelengths, though previously unrecognized due to presentation of curves in different formats, e.g., log, linear. (Red chromatic response curve is largely nonspectral and thus derives from two cones. Close correlation combined with deterministic causation implies cones are the physiological basis of unique hues. This match of three physiological and three psychophysical functions is unique in color vision.

  3. Phylogeography of a Tertiary relict plant, Meconopsis cambrica (Papaveraceae), implies the existence of northern refugia for a temperate herb.

    Science.gov (United States)

    Valtueña, Francisco J; Preston, Chris D; Kadereit, Joachim W

    2012-03-01

    The perennial herb Meconopsis cambrica, a western European endemic, is the only European species of the otherwise Himalayan genus Meconopsis and has been interpreted as a Tertiary relict species. Using rbcL and ITS sequence variation, we date the split between M. cambrica and its sister clade Papaver s.str. to the Middle to Upper Miocene (12.8 Myr, 6.4-19.2 Myr HPD). Within M. cambrica, cpDNA sequence variation reveals the existence of two groups of populations with a comparable level of genetic variation: a northern group from Great Britain, the Massif Central, the western Pyrenees and the Iberian System, and a southern group from the central and eastern Pyrenees. Populations from the Cantabrian Mountains were placed in both groups. Based on ITS sequence variation, the divergence between these two groups can be dated to 1.5 Myr (0.4-2.8 Myr HPD), and the age of the British populations is estimated as 0.37 Myr (0.0-0.9 Myr HPD). Amplified fragment length polymorphism results confirm the distinctive nature of the populations from Britain, the Massif Central and the central and eastern Pyrenees. These patterns of latitudinal variation of M. cambrica differ from patterns of longitudinal differentiation found in many other temperate species and imply glacial survival of the northern populations in northerly refugia. The primary differentiation into northern and southern cpDNA groups dates to near the onset of the Quaternary and suggests that an ancient phylogeographic pattern has survived through several glacial periods. Our data provide evidence that the species has persisted for a long period with a highly fragmented and probably very localized distribution. © 2012 Blackwell Publishing Ltd.

  4. Cone photoreceptor sensitivities and unique hue chromatic responses: correlation and causation imply the physiological basis of unique hues.

    Science.gov (United States)

    Pridmore, Ralph W

    2013-01-01

    This paper relates major functions at the start and end of the color vision process. The process starts with three cone photoreceptors transducing light into electrical responses. Cone sensitivities were once expected to be Red Green Blue color matching functions (to mix colors) but microspectrometry proved otherwise: they instead peak in yellowish, greenish, and blueish hues. These physiological functions are an enigma, unmatched with any set of psychophysical (behavioral) functions. The end-result of the visual process is color sensation, whose essential percepts are unique (or pure) hues red, yellow, green, blue. Unique hues cannot be described by other hues, but can describe all other hues, e.g., that hue is reddish-blue. They are carried by four opponent chromatic response curves but the literature does not specify whether each curve represents a range of hues or only one hue (a unique) over its wavelength range. Here the latter is demonstrated, confirming that opponent chromatic responses define, and may be termed, unique hue chromatic responses. These psychophysical functions also are an enigma, unmatched with any physiological functions or basis. Here both enigmas are solved by demonstrating the three cone sensitivity curves and the three spectral chromatic response curves are almost identical sets (Pearson correlation coefficients r from 0.95-1.0) in peak wavelengths, curve shapes, math functions, and curve crossover wavelengths, though previously unrecognized due to presentation of curves in different formats, e.g., log, linear. (Red chromatic response curve is largely nonspectral and thus derives from two cones.) Close correlation combined with deterministic causation implies cones are the physiological basis of unique hues. This match of three physiological and three psychophysical functions is unique in color vision.

  5. Differences in Radiation Dosimetry and Anorectal Function Testing Imply That Anorectal Symptoms May Arise From Different Anatomic Substrates

    International Nuclear Information System (INIS)

    Smeenk, Robert Jan; Hopman, Wim P.M.; Hoffmann, Aswin L.; Lin, Emile N.J.Th. van; Kaanders, Johannes H.A.M.

    2012-01-01

    . This implies that anal wall and rectal wall should be considered separate organs in radiotherapy planning.

  6. Reduced {sup 123}I-BMIPP uptake implies decreased myocardial flow reserve in patients with chronic stable angina

    Energy Technology Data Exchange (ETDEWEB)

    Kageyama, Hiroyuki; Morita, Koichi; Katoh, Chietsugu; Mabuchi, Megumi; Tamaki, Nagara [Hokkaido University Graduate School of Medicine, Department of Nuclear Medicine, Sapporo (Japan); Tsukamoto, Takahiro; Noriyasu, Kazuyuki; Naya, Masanao [Hokkaido University, Department of Cardiovascular Medicine, Sapporo (Japan); Hokkaido University Graduate School of Medicine, Department of Nuclear Medicine, Sapporo (Japan); Kawai, Yuko [Hokko Memorial Hospital, Department of Cardiovascular Medicine, Sapporo (Japan)

    2006-01-01

    Long-chain fatty acid (LCFA) is the main energy source for normal myocardium at rest, but in ischemic myocardium, the main energy substrate shifts from LCFA to glucose. {sup 123}I-BMIPP is a radiolabeled LCFA analog. In chronic stable angina without previous infarction, we suppose that reduced {sup 123}I-BMIPP uptake is related to the substrate shift in myocardium with decreased myocardial flow reserve (MFR). The purpose of this study was to relate {sup 123}I-BMIPP uptake to rest myocardial blood flow (MBF), hyperemic MBF, and MFR assessed with {sup 15}O-water positron emission tomography (PET). We enrolled 21 patients with chronic stable angina without previous infarction, all of whom underwent {sup 123}I-BMIPP single-photon emission computed tomography (SPECT) and {sup 15}O-water PET. The left ventricle was divided into 13 segments. In each segment, rest MBF and hyperemic MBF were measured by PET. {sup 123}I-BMIPP uptake was evaluated as follows: score 0=normal, 1=slightly decreased uptake, 2=moderately decreased uptake, 3=severely decreased uptake, and 4=complete defect. {sup 123}I-BMIPP uptake was compared with rest MBF, hyperemic MBF, and MFR. The numbers of segments with {sup 123}I-BMIPP scores 0, 1, 2, 3, and 4 were 178, 40, 25, 24, and 0, respectively. The rest MBFs for scores 0, 1, 2, and 3 were 0.93{+-}0.25, 0.86{+-}0.21, 0.97{+-}0.30, and 0.99{+-}0.37 ml/min/g, respectively. The hyperemic MBFs for scores 0, 1, 2, and 3 were 2.76{+-}1.29, 1.84{+-}0.74, 1.37{+-}0.39, and 1.08{+-}0.40 ml/min/g, respectively. The MFRs for scores 0, 1, 2, and 3 were 3.01{+-}1.38, 2.20{+-}0.95, 1.44{+-}0.22, and 1.10{+-}0.26, respectively. As {sup 123}I-BMIPP uptake declined, hyperemic MBF and MFR decreased. In chronic stable angina without previous infarction, reduced {sup 123}I-BMIPP uptake implies decreased MFR. (orig.)

  7. Reduced 123I-BMIPP uptake implies decreased myocardial flow reserve in patients with chronic stable angina.

    Science.gov (United States)

    Kageyama, Hiroyuki; Morita, Koichi; Katoh, Chietsugu; Tsukamoto, Takahiro; Noriyasu, Kazuyuki; Mabuchi, Megumi; Naya, Masanao; Kawai, Yuko; Tamaki, Nagara

    2006-01-01

    Long-chain fatty acid (LCFA) is the main energy source for normal myocardium at rest, but in ischemic myocardium, the main energy substrate shifts from LCFA to glucose. 123I-BMIPP is a radiolabeled LCFA analog. In chronic stable angina without previous infarction, we suppose that reduced 123I-BMIPP uptake is related to the substrate shift in myocardium with decreased myocardial flow reserve (MFR). The purpose of this study was to relate 123I-BMIPP uptake to rest myocardial blood flow (MBF), hyperemic MBF, and MFR assessed with 15O-water positron emission tomography (PET). We enrolled 21 patients with chronic stable angina without previous infarction, all of whom underwent 123I-BMIPP single-photon emission computed tomography (SPECT) and 15O-water PET. The left ventricle was divided into 13 segments. In each segment, rest MBF and hyperemic MBF were measured by PET. 123I-BMIPP uptake was evaluated as follows: score 0=normal, 1=slightly decreased uptake, 2=moderately decreased uptake, 3=severely decreased uptake, and 4=complete defect. 123I-BMIPP uptake was compared with rest MBF, hyperemic MBF, and MFR. The numbers of segments with 123I-BMIPP scores 0, 1, 2, 3, and 4 were 178, 40, 25, 24, and 0, respectively. The rest MBFs for scores 0, 1, 2, and 3 were 0.93+/-0.25, 0.86+/-0.21, 0.97+/-0.30, and 0.99+/-0.37 ml/min/g, respectively. The hyperemic MBFs for scores 0, 1, 2, and 3 were 2.76+/-1.29, 1.84+/-0.74, 1.37+/-0.39, and 1.08+/-0.40 ml/min/g, respectively. The MFRs for scores 0, 1, 2, and 3 were 3.01+/-1.38, 2.20+/-0.95, 1.44+/-0.22, and 1.10+/-0.26, respectively. As 123I-BMIPP uptake declined, hyperemic MBF and MFR decreased. In chronic stable angina without previous infarction, reduced 123I-BMIPP uptake implies decreased MFR.

  8. Reduced 123I-BMIPP uptake implies decreased myocardial flow reserve in patients with chronic stable angina

    International Nuclear Information System (INIS)

    Kageyama, Hiroyuki; Morita, Koichi; Katoh, Chietsugu; Mabuchi, Megumi; Tamaki, Nagara; Tsukamoto, Takahiro; Noriyasu, Kazuyuki; Naya, Masanao; Kawai, Yuko

    2006-01-01

    Long-chain fatty acid (LCFA) is the main energy source for normal myocardium at rest, but in ischemic myocardium, the main energy substrate shifts from LCFA to glucose. 123 I-BMIPP is a radiolabeled LCFA analog. In chronic stable angina without previous infarction, we suppose that reduced 123 I-BMIPP uptake is related to the substrate shift in myocardium with decreased myocardial flow reserve (MFR). The purpose of this study was to relate 123 I-BMIPP uptake to rest myocardial blood flow (MBF), hyperemic MBF, and MFR assessed with 15 O-water positron emission tomography (PET). We enrolled 21 patients with chronic stable angina without previous infarction, all of whom underwent 123 I-BMIPP single-photon emission computed tomography (SPECT) and 15 O-water PET. The left ventricle was divided into 13 segments. In each segment, rest MBF and hyperemic MBF were measured by PET. 123 I-BMIPP uptake was evaluated as follows: score 0=normal, 1=slightly decreased uptake, 2=moderately decreased uptake, 3=severely decreased uptake, and 4=complete defect. 123 I-BMIPP uptake was compared with rest MBF, hyperemic MBF, and MFR. The numbers of segments with 123 I-BMIPP scores 0, 1, 2, 3, and 4 were 178, 40, 25, 24, and 0, respectively. The rest MBFs for scores 0, 1, 2, and 3 were 0.93±0.25, 0.86±0.21, 0.97±0.30, and 0.99±0.37 ml/min/g, respectively. The hyperemic MBFs for scores 0, 1, 2, and 3 were 2.76±1.29, 1.84±0.74, 1.37±0.39, and 1.08±0.40 ml/min/g, respectively. The MFRs for scores 0, 1, 2, and 3 were 3.01±1.38, 2.20±0.95, 1.44±0.22, and 1.10±0.26, respectively. As 123 I-BMIPP uptake declined, hyperemic MBF and MFR decreased. In chronic stable angina without previous infarction, reduced 123 I-BMIPP uptake implies decreased MFR. (orig.)

  9. Biodistribution, pharmacokinetics and uptake ratio of 131I-4-Iodo-phenylacetic acid in normal and tumour implied animals

    International Nuclear Information System (INIS)

    Szuecs, Z.; Sello, T.; Sathekge, M.

    2012-01-01

    per gram of tissue (%ID/g) is given in Table 1 for nine animals as three were considered outliers predominantly due to a high percentage of activity remaining in the tail after injection. The tumour to background ratio was calculated by comparing the muscle on the left flank as opposed to the right flank where the tumour was induced. The labeling via isotopic exchange did yield a low specific activity of the tracer which meant that a substantial amount of 4-iodo-phenylacetic acid was injected. This would amount to 30 μg per rat or 75 μg/kg or 1.1 μg/ml blood (mass of rats 400g and assuming 7% of body weight is blood). The LD50 value for phenyl acetic acid is 1600 mg/kg for intraperitoneal injection in rats which is orders of magnitude higher than the amount injected and therefore one can assume the 0,075 mg/kg injected 4-iodo-phenyl-acetic acid would not adversely interfere with the biological processes in the rat. The amount of phenyl-acetic acid in normal tissue is 16.8 μg/ml which is also a two orders of magnitude higher than the amount of 4-iodophenyl-acetic acid injected. This implies that the biodistribution of the tracer was not influenced by its metabolic product due to equilibrium with phenyl-acetic acid already present in the body. 131 I-4-iodo-phenyl-acetic acid was successfully prepared and the biodistribution in rats recorded. As expected no target organ was found after 5 h (although at the early stages a high cardiac blood pool uptake was recorded) with fast excretion from all organs via the kidney into the urine. In xenograft mice study a 4% tumour uptake and a tumour to background ratio of 2 was recorded after 5 h although high activity levels in the blood still remained at this time point.

  10. Scaling and long-range dependence in option pricing V: Multiscaling hedging and implied volatility smiles under the fractional Black-Scholes model with transaction costs

    Science.gov (United States)

    Wang, Xiao-Tian

    2011-05-01

    This paper deals with the problem of discrete time option pricing using the fractional Black-Scholes model with transaction costs. Through the ‘anchoring and adjustment’ argument in a discrete time setting, a European call option pricing formula is obtained. The minimal price of an option under transaction costs is obtained. In addition, the relation between scaling and implied volatility smiles is discussed.

  11. Time-temperature-burial significance of Devonian anthracite implies former great (approx.6.5 km) depth of burial of Catskill Mountains, New York

    International Nuclear Information System (INIS)

    Friedman, G.M.; Sanders, J.E.

    1982-01-01

    Specimens of coalified plant debris in Tully-correlative strata of the Gilboa Formation (uppermost Middle Devonian) within the eastern Catskill Mountains of New York State have been converted to anthracite having a vitrinite reflectance of 2.5%. This implies a level of organic metamorphism (LOM) of 16. The specimens are about 350 m.y. old; if 200 m.y. is taken as the duration of the time of exposure to the maximum geothermal temperature, then the LOM of 16 and other thermal indicators imply a maximum temperature of 190 0 C. Using a geothermal gradient of 26 0 C.km -1 (17 0 F.1,000 ft -1 ), a former depth of burial of 6.5 km is implied. Such former deep burial is not usually inferred for the Catskills, but it is consistent with the idea that the thick (about 6.4 km or 21,000 ft) Carboniferous strata of northeastern Pennsylvania formerly extended northeast far enough to bury the Catskills. The lack of metamorphism of the Paleozoic strata lying about 4.5 km beneath the Tully-correlative rocks and exposed in the adjacent Hudson Valley places low limits on the former geothermal gradient; this supports the concept of great depth of former burial of the Catskills. For example, 6.5 km of former burial and a geothermal gradient of 26 0 C.km -1 imply a temperature of 307 0 C for the base of the Paleozoic. By contrast, only 1 km of former burial requires a geothermal gradient of 170 0 C.km -1 , which would have subjected the base of the Paleozoic to a temperature of 955 0 GAMMA, which is far higher than the 600 to 650 0 C recently inferred for the Acadian-age metamorphism of the Taconic allochthon in southwestern Massachusetts and adjoining areas

  12. Are Cryptocurrencies the Future of Money? : Whether a Transition to Cryptocurrency, as National Currency of Sweden, Would be Possible and What it Would Imply for the Swedish Society

    OpenAIRE

    Gartz, Madeleine; Linderbrandt, Ida

    2017-01-01

    The underlying technology of cryptocurrencies is a broadly discussed subject. In Sweden, a growing interest for digital assets and payment methods can be observed. The fact that this coincides with an increasing acceptance for cryptocurrencies creates interesting possibilities. Some claim that cryptocurrency could be the future mean of payment. The objective of this report is therefore to examine whether a cryptocurrency could replace the Swedish krona, and what such a transition would imply ...

  13. Vehicle Reference Generator for Collision-Free Trajectories in Hazardous Maneuvers

    Directory of Open Access Journals (Sweden)

    Cuauhtémoc Acosta Lúa

    2018-01-01

    Full Text Available This paper presents a reference generator for ground vehicles, based on potential fields adapted to the case of vehicular dynamics. The reference generator generates signals to be tracked by the vehicle, corresponding to a trajectory avoiding collisions with obstacles. This generator integrates artificial forces of potential fields of the object surrounding the vehicle. The reference generator is used with a controller to ensure the tracking of the accident-free reference. This approach can be used for vehicle autonomous driving or for active control of manned vehicles. Simulation results, presented for the autonomous driving, consider a scenario inspired by the so-called moose (or elk test, with the presence of other collaborative vehicles.

  14. Collision-free inverse kinematics of a 7 link cucumber picking robot

    NARCIS (Netherlands)

    Henten, van E.J.; Schenk, E.J.J.; Willigenburg, van L.G.; Meuleman, J.; Barreiro, P.

    2008-01-01

    The paper presents results of research on inverse kinematics algorithms to be used in a functional model of a cucumber harvesting robot consisting of a redundant manipulator with one prismatic and six rotational joints (P6R). Within a first generic approach, the inverse kinematics problem was

  15. Less than one implies zero

    NARCIS (Netherlands)

    Schwenninger, Felix L.; Zwart, Hans

    2015-01-01

    In this paper we show that from an estimate of the form supt≥0 C(t) - cos(at)I < 1, we can conclude that C(t) equals cos(at)I. Here (C(t)) t≥0 is a strongly continuous cosine family on a Banach space.

  16. Does classical liberalism imply democracy?

    Directory of Open Access Journals (Sweden)

    David Ellerman

    2015-12-01

    Full Text Available There is a fault line running through classical liberalism as to whether or not democratic self-governance is a necessary part of a liberal social order. The democratic and non-democratic strains of classical liberalism are both present today—particularly in the United States. Many contemporary libertarians and neo-Austrian economists represent the non-democratic strain in their promotion of non-democratic sovereign city-states (start-up cities or charter cities. We will take the late James M. Buchanan as a representative of the democratic strain of classical liberalism. Since the fundamental norm of classical liberalism is consent, we must start with the intellectual history of the voluntary slavery contract, the coverture marriage contract, and the voluntary non-democratic constitution (or pactum subjectionis. Next we recover the theory of inalienable rights that descends from the Reformation doctrine of the inalienability of conscience through the Enlightenment (e.g. Spinoza and Hutcheson in the abolitionist and democratic movements. Consent-based governments divide into those based on the subjects’ alienation of power to a sovereign and those based on the citizens’ delegation of power to representatives. Inalienable rights theory rules out that alienation in favor of delegation, so the citizens remain the ultimate principals and the form of government is democratic. Thus the argument concludes in agreement with Buchanan that the classical liberal endorsement of sovereign individuals acting in the marketplace generalizes to the joint action of individuals as the principals in their own organizations.

  17. High spin structure of nuclei near N = 50 shell gap and search for high-spin isomers using time stamped data

    International Nuclear Information System (INIS)

    Saha, S.; Palit, R.; Trivedi, T.; Sethi, J.; Joshi, P.K.; Naidu, B.S.; Donthi, R.; Jadhav, S.; Nanal, V.; Pillay, R.G.; Jain, H.C.; Kumar, S.; Biswas, D.C.; Mukherjee, G.; Saha, S.

    2011-01-01

    Information on the high-spin states of nuclei promises to provide stringent test of the interaction of the Hamiltonian used in the calculation due to smaller basis space for high J-values. It is reported in a recent shell model review that no interaction is optimized for the region of interest around N = 50 and Z = 40 shell closure. The detailed spectroscopic information of the medium and high spin states in these nuclei is required to understand the shape transition between spherical and deformed shapes at N =60 as the higher orbitals are filled. Structure of isomers near shell closure carries important information of, for example, the extent of core excitation. In the present work, the spectroscopic study of the high spin states of 89 Zr isotope have been discussed

  18. Efficient constraint-based Sequential Pattern Mining (SPM algorithm to understand customers’ buying behaviour from time stamp-based sequence dataset

    Directory of Open Access Journals (Sweden)

    Niti Ashish Kumar Desai

    2015-12-01

    Full Text Available Business Strategies are formulated based on an understanding of customer needs. This requires development of a strategy to understand customer behaviour and buying patterns, both current and future. This involves understanding, first how an organization currently understands customer needs and second predicting future trends to drive growth. This article focuses on purchase trend of customer, where timing of purchase is more important than association of item to be purchased, and which can be found out with Sequential Pattern Mining (SPM methods. Conventional SPM algorithms worked purely on frequency identifying patterns that were more frequent but suffering from challenges like generation of huge number of uninteresting patterns, lack of user’s interested patterns, rare item problem, etc. Article attempts a solution through development of a SPM algorithm based on various constraints like Gap, Compactness, Item, Recency, Profitability and Length along with Frequency constraint. Incorporation of six additional constraints is as well to ensure that all patterns are recently active (Recency, active for certain time span (Compactness, profitable and indicative of next timeline for purchase (Length―Item―Gap. The article also attempts to throw light on how proposed Constraint-based Prefix Span algorithm is helpful to understand buying behaviour of customer which is in formative stage.

  19. A TMS study on the contribution of visual area V5 to the perception of implied motion in art and its appreciation.

    Science.gov (United States)

    Cattaneo, Zaira; Schiavi, Susanna; Silvanto, Juha; Nadal, Marcos

    2017-01-01

    Over the last decade, researchers have sought to understand the brain mechanisms involved in the appreciation of art. Previous studies reported an increased activity in sensory processing regions for artworks that participants find more appealing. Here we investigated the intriguing possibility that activity in cortical area V5-a region in the occipital cortex mediating physical and implied motion detection-is related not only to the generation of a sense of motion from visual cues used in artworks, but also to the appreciation of those artworks. Art-naïve participants viewed a series of paintings and quickly judged whether or not the paintings conveyed a sense of motion, and whether or not they liked them. Triple-pulse TMS applied over V5 while viewing the paintings significantly decreased the perceived sense of motion, and also significantly reduced liking of abstract (but not representational) paintings. Our data demonstrate that V5 is involved in extracting motion information even when the objects whose motion is implied are pictorial representations (as opposed to photographs or film frames), and even in the absence of any figurative content. Moreover, our study suggests that, in the case of untrained people, V5 activity plays a causal role in the appreciation of abstract but not of representational art.

  20. On High-Frequency Topography-Implied Gravity Signals for a Height System Unification Using GOCE-Based Global Geopotential Models

    Science.gov (United States)

    Grombein, Thomas; Seitz, Kurt; Heck, Bernhard

    2017-03-01

    National height reference systems have conventionally been linked to the local mean sea level, observed at individual tide gauges. Due to variations in the sea surface topography, the reference levels of these systems are inconsistent, causing height datum offsets of up to ±1-2 m. For the unification of height systems, a satellite-based method is presented that utilizes global geopotential models (GGMs) derived from ESA's satellite mission Gravity field and steady-state Ocean Circulation Explorer (GOCE). In this context, height datum offsets are estimated within a least squares adjustment by comparing the GGM information with measured GNSS/leveling data. While the GNSS/leveling data comprises the full spectral information, GOCE GGMs are restricted to long wavelengths according to the maximum degree of their spherical harmonic representation. To provide accurate height datum offsets, it is indispensable to account for the remaining signal above this maximum degree, known as the omission error of the GGM. Therefore, a combination of the GOCE information with the high-resolution Earth Gravitational Model 2008 (EGM2008) is performed. The main contribution of this paper is to analyze the benefit, when high-frequency topography-implied gravity signals are additionally used to reduce the remaining omission error of EGM2008. In terms of a spectral extension, a new method is proposed that does not rely on an assumed spectral consistency of topographic heights and implied gravity as is the case for the residual terrain modeling (RTM) technique. In the first step of this new approach, gravity forward modeling based on tesseroid mass bodies is performed according to the Rock-Water-Ice (RWI) approach. In a second step, the resulting full spectral RWI-based topographic potential values are reduced by the effect of the topographic gravity field model RWI_TOPO_2015, thus, removing the long to medium wavelengths. By using the latest GOCE GGMs, the impact of topography-implied

  1. A new T2 lesion in a patient with the clinically isolated syndrome does not necessarily imply a conversion to multiple sclerosis.

    Science.gov (United States)

    Capone, Fioravante; Puthenparampil, Marco; Mallio, Carlo Augusto; Celia, Alessandra Ida; Florio, Lucia; Gallo, Paolo; Di Lazzaro, Vincenzo

    2018-01-01

    In the follow-up of patients with the clinically isolated syndrome, both clinical and MRI findings should be carefully evaluated by clinicians to avoid misinterpretation and inappropriate diagnosis of multiple sclerosis. We describe a case of a patient with a previous diagnosis of clinically isolated syndrome who developed a new asymptomatic brain lesion at the MRI follow-up. The careful evaluation of clinical history and radiological findings allowed the correct diagnosis of cocaine-associated ischemic stroke. Our case highlights that, in patients with the clinically isolated syndrome, the appearance of a new lesion on MRI does not necessarily imply a conversion to multiple sclerosis. Among "better explanations", ischemic lesions are of relevance and, in patients without typical risk factors for stroke, rarer causes such as cocaine assumption should be considered. Copyright © 2017 Elsevier B.V. All rights reserved.

  2. Systems with Many Degrees of Freedom: from Mean - Theories of Non-Fermi Liquid Behavior in Impurity Models to Implied Binomial Trees for Modeling Financial Markets

    Science.gov (United States)

    Barle, Stanko

    In this dissertation, two dynamical systems with many degrees of freedom are analyzed. One is the system of highly correlated electrons in the two-impurity Kondo problem. The other deals with building a realistic model of diffusion underlying financial markets. The simplest mean-field theory capable of mimicking the non-Fermi liquid behavior of the critical point in the two-impurity Kondo problem is presented. In this approach Landau's adiabaticity assumption--of a one-to-one correspondence between the low-energy excitations of the interacting and noninteracting systems--is violated through the presence of decoupled local degrees of freedom. These do not couple directly to external fields but appear indirectly in the physical properties leading, for example, to the log(T, omega) behavior of the staggered magnetic susceptibility. Also, as observed previously, the correlation function = -1/4 is a consequence of the equal weights of the singlet and triplet impurity configurations at the critical point. In the second problem, a numerical model is developed to describe the diffusion of prices in the market. Implied binomial (or multinomial) trees are constructed to enable practical pricing of derivative securities in consistency with the existing market. The method developed here is capable of accounting for both the strike price and term structure of the implied volatility. It includes the correct treatment of interest rate and dividends which proves robust even if these quantities are unusually large. The method is explained both as a set of individual innovations and, from a different prospective, as a consequence of a single plausible transformation from the tree of spot prices to the tree of futures prices.

  3. The accretion of solar material onto white dwarfs: No mixing with core material implies that the mass of the white dwarf is increasing

    Directory of Open Access Journals (Sweden)

    Sumner Starrfield

    2014-02-01

    Full Text Available Cataclysmic Variables (CVs are close binary star systems with one component a white dwarf (WD and the other a larger cooler star that fills its Roche Lobe. The cooler star is losing mass through the inner Lagrangian point of the binary and some unknown fraction of this material is accreted by the WD. One consequence of the WDs accreting material, is the possibility that they are growing in mass and will eventually reach the Chandrasekhar Limit. This evolution could result in a Supernova Ia (SN Ia explosion and is designated the Single Degenerate Progenitor (SD scenario. This paper is concerned with the SD scenario for SN Ia progenitors. One problem with the single degenerate scenario is that it is generally assumed that the accreting material mixes with WD core material at some time during the accretion phase of evolution and, since the typical WD has a carbon-oxygen CO core, the mixing results in large amounts of carbon and oxygen being brought up into the accreted layers. The presence of enriched carbon causes enhanced nuclear fusion and a Classical Nova explosion. Both observations and theoretical studies of these explosions imply that more mass is ejected than is accreted. Thus, the WD in a Classical Nova system is losing mass and cannot be a SN Ia progenitor. However, the composition in the nuclear burning region is important and, in new calculations reported here, the consequences to the WD of no mixing of accreted material with core material have been investigated so that the material involved in the explosion has only a Solar composition. WDs with a large range in initial masses and mass accretion rates have been evolved. I find that once sufficient material has been accreted, nuclear burning occurs in all evolutionary sequences and continues until a thermonuclear runaway (TNR occurs and the WD either ejects a small amount of material or its radius grows to about 1012 cm and the evolution is ended. In all cases where mass ejection occurs

  4. Dynamical critical scaling of electric field fluctuations in the greater cusp and magnetotail implied by HF radar observations of F-region Doppler velocity

    Directory of Open Access Journals (Sweden)

    M. L. Parkinson

    2006-03-01

    Full Text Available Akasofu's solar wind ε parameter describes the coupling of solar wind energy to the magnetosphere and ionosphere. Analysis of fluctuations in ε using model independent scaling techniques including the peaks of probability density functions (PDFs and generalised structure function (GSF analysis show the fluctuations were self-affine (mono-fractal, single exponent scaling over 9 octaves of time scale from ~46 s to ~9.1 h. However, the peak scaling exponent α0 was a function of the fluctuation bin size, so caution is required when comparing the exponents for different data sets sampled in different ways. The same generic scaling techniques revealed the organisation and functional form of concurrent fluctuations in azimuthal magnetospheric electric fields implied by SuperDARN HF radar measurements of line-of-sight Doppler velocity, vLOS, made in the high-latitude austral ionosphere. The PDFs of vLOS fluctuation were calculated for time scales between 1 min and 256 min, and were sorted into noon sector results obtained with the Halley radar, and midnight sector results obtained with the TIGER radar. The PDFs were further sorted according to the orientation of the interplanetary magnetic field, as well as ionospheric regions of high and low Doppler spectral width. High spectral widths tend to occur at higher latitude, mostly on open field lines but also on closed field lines just equatorward of the open-closed boundary, whereas low spectral widths are concentrated on closed field lines deeper inside the magnetosphere. The vLOS fluctuations were most self-affine (i.e. like the solar wind ε parameter on the high spectral width field lines in the noon sector ionosphere (i.e. the greater cusp, but suggested multi-fractal behaviour on closed field lines in the midnight sector (i.e. the central plasma sheet. Long tails in the PDFs imply that "microbursts" in ionospheric convection

  5. Dynamical critical scaling of electric field fluctuations in the greater cusp and magnetotail implied by HF radar observations of F-region Doppler velocity

    Directory of Open Access Journals (Sweden)

    M. L. Parkinson

    2006-03-01

    Full Text Available Akasofu's solar wind ε parameter describes the coupling of solar wind energy to the magnetosphere and ionosphere. Analysis of fluctuations in ε using model independent scaling techniques including the peaks of probability density functions (PDFs and generalised structure function (GSF analysis show the fluctuations were self-affine (mono-fractal, single exponent scaling over 9 octaves of time scale from ~46 s to ~9.1 h. However, the peak scaling exponent α0 was a function of the fluctuation bin size, so caution is required when comparing the exponents for different data sets sampled in different ways. The same generic scaling techniques revealed the organisation and functional form of concurrent fluctuations in azimuthal magnetospheric electric fields implied by SuperDARN HF radar measurements of line-of-sight Doppler velocity, vLOS, made in the high-latitude austral ionosphere. The PDFs of vLOS fluctuation were calculated for time scales between 1 min and 256 min, and were sorted into noon sector results obtained with the Halley radar, and midnight sector results obtained with the TIGER radar. The PDFs were further sorted according to the orientation of the interplanetary magnetic field, as well as ionospheric regions of high and low Doppler spectral width. High spectral widths tend to occur at higher latitude, mostly on open field lines but also on closed field lines just equatorward of the open-closed boundary, whereas low spectral widths are concentrated on closed field lines deeper inside the magnetosphere. The vLOS fluctuations were most self-affine (i.e. like the solar wind ε parameter on the high spectral width field lines in the noon sector ionosphere (i.e. the greater cusp, but suggested multi-fractal behaviour on closed field lines in the midnight sector (i.e. the central plasma sheet. Long tails in the PDFs imply that "microbursts" in ionospheric convection occur far more frequently, especially on open field lines, than can be

  6. The spatiotemporal dynamic analysis of the implied market information and characteristics of the correlation coefficient matrix of the international crude oil price returns

    International Nuclear Information System (INIS)

    Tian, Lixin; Ding, Zhenqi; Zhen, Zaili; Wang, Minggang

    2016-01-01

    The international crude oil market plays a crucial role in economies, and the studies of the correlation, risk and synchronization of the international crude oil market have important implications for the security and stability of the country, avoidance of business risk and people's daily lives. We investigate the information and characteristics of the international crude oil market (1999-2015) based on the random matrix theory (RMT). Firstly, we identify richer information in the largest eigenvalues deviating from RMT predictions for the international crude oil market; the international crude oil market can be roughly divided into ten different periods by the methods of eigenvectors and characteristic combination, and the implied market information of the correlation coefficient matrix is advanced. Secondly, we study the characteristics of the international crude oil market by the methods of system risk entropy, dynamic synchronous ratio, dynamic non-synchronous ratio and dynamic clustering algorithm. The results show that the international crude oil market is full of risk. The synchronization of the international crude oil market is very strong, and WTI and Brent occupy a very important position in the international crude oil market. (orig.)

  7. Health Complaints Associated with Poor Rental Housing Conditions in Arkansas: The Only State without a Landlord’s Implied Warranty of Habitability

    Science.gov (United States)

    Bachelder, Ashley E.; Stewart, M. Kate; Felix, Holly C.; Sealy, Neil

    2016-01-01

    Arkansas is the only U.S. state that does not have a landlord’s implied warranty of habitability, meaning tenants have a requirement for maintaining their rental properties at certain habitability standards, but landlords are not legally required to contribute to those minimum health and safety standards. This project assessed the possibility that this lack of landlord responsibility affects tenants’ perceived health. Using surveys and interviews, we collected self-reported data on the prevalence and description of problems faced by renters who needed household repairs from their landlords. Of almost 1,000 renters, one-third of them had experienced a problem with their landlord making needed repairs; and one-quarter of those had a health issue they attributed to their housing conditions. Common issues included problems with plumbing, heating, or cooling systems, and pest or rodent control. Reported health problems included elevated stress levels, breathing problems, headaches, high blood pressure, and bites or infections. Hispanic respondents and those with less than a high school education were both significantly more likely to report problems with their landlords not making repairs as requested. These data suggest that the lack of landlord requirements may negatively impact the condition of rental properties and, therefore, may negatively impact the health of Arkansas renters. PMID:27933288

  8. Health Complaints Associated with Poor Rental Housing Conditions in Arkansas: The Only State Without a Landlord’s Implied Warranty of Habitability

    Directory of Open Access Journals (Sweden)

    Ashley Bachelder

    2016-11-01

    Full Text Available Arkansas is the only U.S. state that does not have a landlord’s implied warranty of habitability, meaning tenants have a requirement for maintaining their rental properties at certain habitability standards, but landlords are not legally required to contribute to those minimum health and safety standards. This project assessed the possibility that this lack of landlord responsibility affects tenants’ perceived health. Using surveys and interviews, we collected self-reported data on the prevalence and description of problems faced by renters who needed household repairs from their landlords. Of almost 1000 renters, one third of them had experienced a problem with their landlord making needed repairs; and one-quarter of those had a health issue they attributed to their housing conditions. Common issues included problems with plumbing, heating or cooling systems, and pest or rodent control. Reported health problems included elevated stress levels, breathing problems, headaches, high blood pressure and bites or infections. Hispanic respondents and those with less than a high school education were both significantly more likely to report problems with their landlords not making repairs as requested. The data suggest that the lack of landlord requirements may negatively impact the condition of rental properties, and therefore may negatively impact the health of Arkansas renters.

  9. High temporal and spatial diversity in marine RNA viruses implies that they have an important role in mortality and structuring plankton communities

    Directory of Open Access Journals (Sweden)

    Julia Anne Gustavsen

    2014-12-01

    Full Text Available Viruses in the order Picornavirales infect eukaryotes, and are widely distributed in coastal waters. Amplicon deep-sequencing of the RNA dependent RNA polymerase (RdRp revealed diverse and highly uneven communities of picorna-like viruses in the coastal waters of British Columbia (B.C., Canada. Almost 300 000 pyrosequence reads revealed 145 operational taxonomic units (OTUs based on 95% sequence similarity at the amino-acid level. Each sample had between 24 and 71 OTUs and there was little overlap among samples. Phylogenetic analysis revealed that some clades of OTUs were only found at one site; whereas, other groups included OTUs from all sites. Since most of these OTUs are likely from viruses that infect eukaryotic phytoplankton, and viral isolates infecting phytoplankton are strain-specific; each OTU probably arose from the lysis of a specific phytoplankton taxon. Moreover, the patchiness in OTU distribution, and the high turnover of viruses in the mixed layer, implies continuous infection and lysis by RNA viruses of a diverse array of eukaryotic phytoplankton taxa. Hence, these viruses are likely important elements structuring the phytoplankton community, and play a significant role in nutrient cycling and energy transfer.

  10. The spatiotemporal dynamic analysis of the implied market information and characteristics of the correlation coefficient matrix of the international crude oil price returns

    Energy Technology Data Exchange (ETDEWEB)

    Tian, Lixin [Jiangsu University, Energy Development and Environmental Protection Strategy Research Center, Zhenjiang, Jiangsu (China); Nanjing Normal University, School of Mathematical Sciences, Nanjing, Jiangsu (China); Ding, Zhenqi; Zhen, Zaili [Jiangsu University, Energy Development and Environmental Protection Strategy Research Center, Zhenjiang, Jiangsu (China); Wang, Minggang [Nanjing Normal University, School of Mathematical Sciences, Nanjing, Jiangsu (China)

    2016-08-15

    The international crude oil market plays a crucial role in economies, and the studies of the correlation, risk and synchronization of the international crude oil market have important implications for the security and stability of the country, avoidance of business risk and people's daily lives. We investigate the information and characteristics of the international crude oil market (1999-2015) based on the random matrix theory (RMT). Firstly, we identify richer information in the largest eigenvalues deviating from RMT predictions for the international crude oil market; the international crude oil market can be roughly divided into ten different periods by the methods of eigenvectors and characteristic combination, and the implied market information of the correlation coefficient matrix is advanced. Secondly, we study the characteristics of the international crude oil market by the methods of system risk entropy, dynamic synchronous ratio, dynamic non-synchronous ratio and dynamic clustering algorithm. The results show that the international crude oil market is full of risk. The synchronization of the international crude oil market is very strong, and WTI and Brent occupy a very important position in the international crude oil market. (orig.)

  11. Contributions of China’s Wood-Based Panels to CO2 Emission and Removal Implied by the Energy Consumption Standards

    Directory of Open Access Journals (Sweden)

    Shanshan Wang

    2017-07-01

    Full Text Available Life cycle analysis on wood-based panels in terms of CO2 flux can be used to quantitatively assess the climate change contributions of these materials. In this study, the annual CO2 flux between 1990 and 2015 was calculated through gate-to-gate life cycle analysis of wood-based panels. As implied by the energy consumption standards, China’s wood-based panels used to be carbon sources during the period 1990–2007, with the average contribution to CO2 emissions of 9.20 Mt/year. The implementation of new standards and the development of Cleaner production technologies in China, decreased the energy consumption per panel. China’s wood-based panels acted as a carbon sink between 2008 and 2015, with the average contribution to CO2 removal of 31.71 Mt/year. Plywood produced the largest contributions to the emission and removal of CO2, and was followed by fiberboard and particleboard. China’s wood-based panels, with good prospects and strong demands projected in the future, can potentially contribute to climate change mitigation.

  12. Analysis of Knickzones over a Coastal Mountain Range of the Korean Peninsula Implies Intensive Uplifts during the Opening of the East Sea

    Science.gov (United States)

    Byun, J.; Paik, K.

    2017-12-01

    coastal mountain range had not persisted over the Pliocene, and instead the coastal mountain range had developed mostly during the opening of the East Sea, implying that the formation of the coastal mountain range is mainly attributed to the drifting of the Japanese Islands from the Korean Peninsula and consequent opening of the East Sea.

  13. Biomimetically grown apatite spheres from aggregated bioglass nanoparticles with ultrahigh porosity and surface area imply potential drug delivery and cell engineering applications.

    Science.gov (United States)

    El-Fiqi, Ahmed; Buitrago, Jennifer O; Yang, Sung Hee; Kim, Hae-Won

    2017-09-15

    Here we communicate the generation of biomimetically grown apatite spheres from aggregated bioglass nanoparticles and the potential properties applicable for drug delivery and cell/tissue engineering. Ion releasing nanoparticulates of bioglass (85%SiO 2 -15%CaO) in a mineralizing medium show an intriguing dynamic phenomenon - aggregation, mineralization to apatite, integration and growth into micron-sized (1.5-3μm) spheres. During the progressive ionic dissolution/precipitation reactions, nano-to-micro-morphology, glass-to-crystal composition, and the physico-chemical properties (porosity, surface area, and charge) change dynamically. With increasing reaction period, the apatite becomes more crystallized with increased crystallinity and crystal size, and gets a composition closer to the stoichiometry. The developed microspheres exhibit hierarchical surface nanostructure, negative charge (ς-potential of -20mV), and ultrahigh mesoporosity (mesopore size of 6.1nm, and the resultant surface area of 63.7m 2 /g and pore volume of 0.153cm 3 /g) at 14days of mineralization, which are even higher than those of its precursor bioglass nanoparticles. Thanks to these properties, the biomimetic mineral microspheres take up biological molecules effectively, i.e., loading capacity of positive-charged protein is over 10%. Of note, the release is highly sustainable at a constant rate, i.e., profiling almost 'zero-order' kinetics for 4weeks, suggesting the potential usefulness as protein delivery systems. The biomimetic mineral microspheres hold some remnant Si in the core region, and release calcium, phosphate, and silicate ions over the test period, implying the long-term ionic-related therapeutic functions. The mesenchymal stem cells favour the biomimetic spheres with an excellent viability. Due to the merit of sizes (a few micrometers), the spheres can be intercalated into cells, mediating cellular interactions in 3D cell-spheroid engineering, and also can stimulate osteogenic

  14. Collision-free inverse kinematics of the redundant seven link manipulator used in a cucumber harvesting robot

    NARCIS (Netherlands)

    Henten, van E.J.; Schenk, E.J.J.; Willigenburg, van L.G.; Meuleman, J.; Barreiro, P.

    2010-01-01

    The paper presents results of research on an inverse kinematics algorithm that has been used in a functional model of a cucumber-harvesting robot consisting of a redundant P6R manipulator. Within a first generic approach, the inverse kinematics problem was reformulated as a non-linear programming

  15. Study and treatment of situations implying radon

    International Nuclear Information System (INIS)

    Robe, M.Ch.

    2005-01-01

    The radon is a radioactive gas with a natural origin. It comes from a disintegration of uranium and radium present in the soils. It comes from granitic and volcanic subsoils. The radon can accumulate in buildings. It is the principal source of natural exposure and the second one after medical exposures. It is the only one source of radiations on which man is susceptible to act. Ventilation and airtightness are solutions to reduce radon concentration. (N.C.)

  16. Meteorite Dichotomy Implies that Jupiter Formed Early

    Science.gov (United States)

    Kruijer, T. S.; Burkhardt, C.; Budde, G.; Kleine, T.

    2018-05-01

    Meteorites derive from two distinct nebular reservoirs that co-existed and remained spatially separated between 1 and 3–4 Ma after CAIs. This can most easily be explained if Jupiter acted as a barrier and formed early, within less than 1 Ma.

  17. Index options : Pricing, implied densities and returns

    NARCIS (Netherlands)

    Boes, M.J.

    2006-01-01

    Chapter 2 gives an overview of the literature that is directly related to the topics studied in this thesis. In Chapter 3 the impact of overnight periods on option prices is examined by estimating an option pricing model that takes overnight closures of exchanges explicitly into account. Chapter 4

  18. Endogenous population growth may imply chaos.

    Science.gov (United States)

    Prskawetz, A; Feichtinger, G

    1995-01-01

    The authors consider a discrete-time neoclassical growth model with an endogenous rate of population growth. The resulting one-dimensional map for the capital intensity has a tilted z-shape. Using the theory of nonlinear dynamical systems, they obtain numerical results on the qualitative behavior of time paths for changing parameter values. Besides stable and periodic solutions, erratic time paths may result. In particular, myopic and far-sighted economies--assumed to be characterized by low and high savings rate respectively--are characterized by stable per capita capital stocks, while solutions with chaotic windows exist between these two extremes.

  19. Climate change: believing and seeing implies adapting.

    Science.gov (United States)

    Blennow, Kristina; Persson, Johannes; Tomé, Margarida; Hanewinkel, Marc

    2012-01-01

    Knowledge of factors that trigger human response to climate change is crucial for effective climate change policy communication. Climate change has been claimed to have low salience as a risk issue because it cannot be directly experienced. Still, personal factors such as strength of belief in local effects of climate change have been shown to correlate strongly with responses to climate change and there is a growing literature on the hypothesis that personal experience of climate change (and/or its effects) explains responses to climate change. Here we provide, using survey data from 845 private forest owners operating in a wide range of bio-climatic as well as economic-social-political structures in a latitudinal gradient across Europe, the first evidence that the personal strength of belief and perception of local effects of climate change, highly significantly explain human responses to climate change. A logistic regression model was fitted to the two variables, estimating expected probabilities ranging from 0.07 (SD ± 0.01) to 0.81 (SD ± 0.03) for self-reported adaptive measures taken. Adding socio-demographic variables improved the fit, estimating expected probabilities ranging from 0.022 (SD ± 0.008) to 0.91 (SD ± 0.02). We conclude that to explain and predict adaptation to climate change, the combination of personal experience and belief must be considered.

  20. Climate change: believing and seeing implies adapting.

    Directory of Open Access Journals (Sweden)

    Kristina Blennow

    Full Text Available Knowledge of factors that trigger human response to climate change is crucial for effective climate change policy communication. Climate change has been claimed to have low salience as a risk issue because it cannot be directly experienced. Still, personal factors such as strength of belief in local effects of climate change have been shown to correlate strongly with responses to climate change and there is a growing literature on the hypothesis that personal experience of climate change (and/or its effects explains responses to climate change. Here we provide, using survey data from 845 private forest owners operating in a wide range of bio-climatic as well as economic-social-political structures in a latitudinal gradient across Europe, the first evidence that the personal strength of belief and perception of local effects of climate change, highly significantly explain human responses to climate change. A logistic regression model was fitted to the two variables, estimating expected probabilities ranging from 0.07 (SD ± 0.01 to 0.81 (SD ± 0.03 for self-reported adaptive measures taken. Adding socio-demographic variables improved the fit, estimating expected probabilities ranging from 0.022 (SD ± 0.008 to 0.91 (SD ± 0.02. We conclude that to explain and predict adaptation to climate change, the combination of personal experience and belief must be considered.

  1. Handicap principle implies emergence of dimorphic ornaments.

    Science.gov (United States)

    Clifton, Sara M; Braun, Rosemary I; Abrams, Daniel M

    2016-11-30

    Species spanning the animal kingdom have evolved extravagant and costly ornaments to attract mating partners. Zahavi's handicap principle offers an elegant explanation for this: ornaments signal individual quality, and must be costly to ensure honest signalling, making mate selection more efficient. Here, we incorporate the assumptions of the handicap principle into a mathematical model and show that they are sufficient to explain the heretofore puzzling observation of bimodally distributed ornament sizes in a variety of species. © 2016 The Author(s).

  2. Anesthesiological ethics: can informed consent be implied?

    Science.gov (United States)

    Spike, Jeffrey R

    2012-01-01

    Surgical ethics is a well-recognized field in clinical ethics, distinct from medical ethics. It includes at least a dozen important issues common to surgery that do not exist in internal medicine simply because of the differences in their practices. But until now there has been a tendency to include ethical issues of anesthesiology as a part of surgical ethics. This may mask the importance of ethical issues in anesthesiology, and even help perpetuate an unfortunate view that surgeons are "captain of the ship" in the operating theater (leaving anesthesiologists in a subservient role). We will have a better ethical understanding if we see surgery and anesthesia as two equal partners, ethically as well as in terms of patient care. Informed consent is one such issue, but it is not limited to that. Even on the topic of what type of anesthesia to use, anesthesiologists have often felt subsumed to the surgeon's preferences. This commentary takes the case study and uses it as a exemplar for this very claim: it is time to give due recognition for a new field in clinical ethics, ethics in anesthesia.

  3. Applied and implied semantics in crystallographic publishing

    Directory of Open Access Journals (Sweden)

    McMahon Brian

    2012-08-01

    Full Text Available Abstract Background Crystallography is a data-rich, software-intensive scientific discipline with a community that has undertaken direct responsibility for publishing its own scientific journals. That community has worked actively to develop information exchange standards allowing readers of structure reports to access directly, and interact with, the scientific content of the articles. Results Structure reports submitted to some journals of the International Union of Crystallography (IUCr can be automatically validated and published through an efficient and cost-effective workflow. Readers can view and interact with the structures in three-dimensional visualization applications, and can access the experimental data should they wish to perform their own independent structure solution and refinement. The journals also layer on top of this facility a number of automated annotations and interpretations to add further scientific value. Conclusions The benefits of semantically rich information exchange standards have revolutionised the scholarly publishing process for crystallography, and establish a model relevant to many other physical science disciplines.

  4. Devaney chaos plus shadowing implies distributional chaos.

    Science.gov (United States)

    Li, Jian; Li, Jie; Tu, Siming

    2016-09-01

    We explore connections among the regional proximal relation, the asymptotic relation, and the distal relation for a topological dynamical system with the shadowing property and show that if a Devaney chaotic system has the shadowing property then it is distributionally chaotic.

  5. Does staff diversity imply openness to diversity?

    DEFF Research Database (Denmark)

    Lauring, Jakob; Selmer, Jan

    2013-01-01

    Purpose – Post-secondary educational organizations are currently some of the most diverse settings to be found. However, few educational studies have dealt with staff diversity and hardly any has looked outside the USA. The purpose of this paper is to present a study of members of international...... university departments in Denmark. The authors set out to investigate the relationship between different types of staff diversity and openness to diversity in terms of linguistic, visible, value, and informational heterogeneity. Design/methodology/approach – This study uses responses from 489 staff members......, was unrelated or negatively associated with positive diversity attitudes. Originality/value – Few studies deal with the role of staff diversity and no prior studies the authors know of have examined the link between diversity types and openness to diversity....

  6. A Hull and White Formula for a General Stochastic Volatility Jump-Diffusion Model with Applications to the Study of the Short-Time Behavior of the Implied Volatility

    Directory of Open Access Journals (Sweden)

    Elisa Alòs

    2008-01-01

    Full Text Available We obtain a Hull and White type formula for a general jump-diffusion stochastic volatility model, where the involved stochastic volatility process is correlated not only with the Brownian motion driving the asset price but also with the asset price jumps. Towards this end, we establish an anticipative Itô's formula, using Malliavin calculus techniques for Lévy processes on the canonical space. As an application, we show that the dependence of the volatility process on the asset price jumps has no effect on the short-time behavior of the at-the-money implied volatility skew.

  7. Metacognition does not imply self-reflection, but it does imply function.

    Science.gov (United States)

    Hoffman, Megan L; Schwartz, Bennett L

    2014-05-01

    Is self-reflection necessary for metacognition to occur? Like Kornell (2014, pp. 143-149), we struggle with this question. If humans metacognition is not always self-reflective, why should we expect animals to be so? We suggest that one way to pursue metacognition in animals is to examine its ecological and evolutionary relevance. ©2014 APA, all rights reserved.

  8. What SMART Technology implies for the industry of the future

    CSIR Research Space (South Africa)

    Annamalai, Leeandran

    2017-10-01

    Full Text Available This presentation discusses how SMART technology can influence the industry of the future. Topics touched on are software enabled machines able to respond relevantly to real world events, the industrial Internet of Things, and machines measurements...

  9. Banal and Implied Forms of Violence in Levinas' Phenomenological Ethics

    OpenAIRE

    Fleurdeliz R. Altez

    2007-01-01

    Despite his final call for peace and "the wisdom of love", Emmanuel Levinas inevitably spoke of violence, and perhaps spoke even more of it. His call for infinite responsibility is actually crystallized through discourse on violence and suffering. We may say that these themes served as catalysts to the standing theory and, ethically, to any responsible Self. Violence, at least as a concept, poses itself as a significant presence to Levinas' plantilla while it reaches unexplored dimensions tha...

  10. Does the evolutionary conservation of microsatellite loci imply function?

    Energy Technology Data Exchange (ETDEWEB)

    Shriver, M.D.; Deka, R.; Ferrell, R.E. [Univ. of Pittsburgh, PA (United States)] [and others

    1994-09-01

    Microsatellites are highly polymorphic tandem arrays of short (1-6 bp) sequence motifs which have been found widely distributed in the genomes of all eukaryotes. We have analyzed allele frequency data on 16 microsatellite loci typed in the great apes (human, chimp, orangutan, and gorilla). The majority of these loci (13) were isolated from human genomic libraries; three were cloned from chimpanzee genomic DNA. Most of these loci are not only present in all apes species, but are polymorphic with comparable levels of heterozygosity and have alleles which overlap in size. The extent of divergence of allele frequencies among these four species were studies using the stepwise-weighted genetic distance (Dsw), which was previously shown to conform to linearity with evolutionary time since divergence for loci where mutations exist in a stepwise fashion. The phylogenetic tree of the great apes constructed from this distance matrix was consistent with the expected topology, with a high bootstrap confidence (82%) for the human/chimp clade. However, the allele frequency distributions of these species are 10 times more similar to each other than expected when they were calibrated with a conservative estimate of the time since separation of humans and the apes. These results are in agreement with sequence-based surveys of microsatellites which have demonstrated that they are highly (90%) conserved over short periods of evolutionary time (< 10 million years) and moderately (30%) conserved over long periods of evolutionary time (> 60-80 million years). This evolutionary conservation has prompted some authors to speculate that there are functional constraints on microsatellite loci. In contrast, the presence of directional bias of mutations with constraints and/or selection against aberrant sized alleles can explain these results.

  11. Modeling Autoregressive Processes with Moving-Quantiles-Implied Nonlinearity

    Directory of Open Access Journals (Sweden)

    Isao Ishida

    2015-01-01

    Full Text Available We introduce and investigate some properties of a class of nonlinear time series models based on the moving sample quantiles in the autoregressive data generating process. We derive a test fit to detect this type of nonlinearity. Using the daily realized volatility data of Standard & Poor’s 500 (S&P 500 and several other indices, we obtained good performance using these models in an out-of-sample forecasting exercise compared with the forecasts obtained based on the usual linear heterogeneous autoregressive and other models of realized volatility.

  12. Lorentz covariance ‘almost’ implies electromagnetism and more

    International Nuclear Information System (INIS)

    Sobouti, Y

    2015-01-01

    Beginning from two simple assumptions, (i) the speed of light is a universal constant, or its equivalent, the spacetime intervals are Lorentz invariant, and (ii) there are mutually interacting particles, with a covariant ‘source-field’ equation, one arrives at a class of field equations of which the standard electromagnetism (EM) and electrodynamics are special cases. The formalism, depending on how one formulates the source-field equation, allows one to speculate magnetic monopoles, massive photons, nonlinear EMs, and more. (paper)

  13. Quantum communication complexity advantage implies violation of a Bell inequality

    NARCIS (Netherlands)

    H. Buhrman (Harry); L. Czekaj (Lłukasz); A. Grudka (Andrzej); M. Horodecki (Michalł); P. Horodecki (Pawelł); M. Markiewicz (Marcin); F. Speelman (Florian); S. Strelchuk (Sergii)

    2016-01-01

    textabstractWe obtain a general connection between a large quantumadvantage in communication complexity and Bell nonlocality. We show that given any protocol offering a sufficiently large quantum advantage in communication complexity, there exists a way of obtaining measurement statistics that

  14. Do superheavy elements imply the existence of black holes

    International Nuclear Information System (INIS)

    Pringle, J.E.; Dearborn, D.S.P.; Fabian, A.C.

    1976-01-01

    Some comments are offered on the question of where superheavy elements, such as elements 116, 124 and 126, are likely to have been formed. Most of these elements are thought to have been produced under conditions of explosive nucleosynthesis by what is known as the 'r-process', and particularly in conventional supernova explosions, but it is stated that the ability of the r-process to produce superheavy elements is very uncertain, and the conditions necessary for synthesis of these elements are difficult to realise in astrophysical situations. It is thought that superheavy elements exist in the outer layers of neutron stars, and ideal conditions for the production of superheavy nuclei, such as high neutron flux and rapid β decays, occur in the disruption of a neutron star. Such disruption is possible in two ways, both of which involve a black hole. It is likely that a neutron star is disrupted when it accretes sufficient material for its mass to exceed the maximum mass for stability, and it then has no alternative but to collapse to form a black hole and it seems possible that some of the outer layers are thrown off during the process. It is thus argued that the most likely site for the production of superheavy elements is in the surface layers of a neutron star, and the most plausible means by which these layers can be returned to the interstellar medium involves the intervention or formation of a black hole. (U.K.)

  15. Green product development : What does the country product space imply?

    NARCIS (Netherlands)

    Fraccascia, Luca; Giannoccaro, Ilaria; Albino, Vito

    This paper contributes to green product development by identifying the green products with the highest potential for growth in a country. To address our aim, we use the concept of product proximity and product space and, borrowing from the results of recent studies on complexity economics, we

  16. School Finance Reform: Do Equalized Expenditures Imply Equalized Teacher Salaries?

    Science.gov (United States)

    Streams, Meg; Butler, J. S.; Cowen, Joshua; Fowles, Jacob; Toma, Eugenia F.

    2011-01-01

    Kentucky is a poor, relatively rural state that contrasts greatly with the relatively urban and wealthy states typically the subject of education studies employing large-scale administrative data. For this reason, Kentucky's experience of major school finance and curricular reform is highly salient for understanding teacher labor market dynamics.…

  17. Modeling of CPDOs - Identifying Optimal and Implied Leverage

    DEFF Research Database (Denmark)

    Dorn, Jochen

    famous notably by Standard & Poor's rating model error which illustrated that closed-form analytical pricing is necessary in order to evaluate and understand complex derivatives. This article aims to shed a light on CPDOs specific structural enhancements and mechanisms. The author quantifies inherent...... risks and provides a dynamic closed-form pricing formula....

  18. Modeling of CPDOs - Identifying optimal and implied leverage

    DEFF Research Database (Denmark)

    Dorn, Jochen

    2010-01-01

    by Standard & Poor's rating model error which illustrated that closed-form analytical pricing is necessary in order to evaluate and understand complex derivatives. This article aims to shed a light on CPDOs' specific structural enhancements and mechanisms. We quantify inherent risks and provide a dynamic...

  19. Modeling of CPDOs - Identifying Optimal and Implied Leverage

    DEFF Research Database (Denmark)

    Dorn, Jochen

    When the subprime crisis started emerging, collateralized products based on Credit Default Swap (CDS) exposures combined with security features seemed to be a more rational alternative to classic asset backed securities. Constant Proportion Collateralized Debt Obligations (CPDOs) are a mixture...... risks and provides a dynamic closed-form pricing formula....

  20. I Fought the Law: Transgressive Play and The Implied Player

    DEFF Research Database (Denmark)

    Aarseth, Espen J.

    2007-01-01

    This paper is an attempt to understand Game Studies through the contested notion of the “player” both inside and outside “the game object” – that is the object that game users perceive and respond to when they play. Building on Hans-Georg Gadamer’s notion of games as a subject that “masters...... the players”, the paper will go beyond the traditional split between the social sciences’ real players and the aesthetics/humanities critical author-as-player, and present a theory of the player and player studies that incorporates the complex tensions between the real, historical player and the game’s human...... components. Since games are both aesthetic and social phenomena, a theory of the player must combine both social and aesthetic perspectives to be successful. The tension between the humanities and the social sciences over who controls the idea of the player can be found mirrored also in the struggle between...

  1. The Phenomena Implied by the New Economy from Statistics Perspective

    Directory of Open Access Journals (Sweden)

    Giani GRADINARU

    2006-01-01

    Full Text Available The rapidity of the informational society to transform into an information and knowledge society determines a perspective on the New Economy which would consider the Internet market and the effect of the Internet information on all economic agents, and the effect of knowledge as economic factor, which imposes the recognition of intangible goods, in general, in the making of economic value as well as the requirements for achieving a lasting society, which cannot be possible but inside the knowledge society, and which would impose in the society economy new technologies, and most important, changes in orientation according to the classic economic thinking.

  2. Chaotic expression dynamics implies pluripotency: when theory and experiment meet

    Directory of Open Access Journals (Sweden)

    Furusawa Chikara

    2009-05-01

    Full Text Available Abstract Background During normal development, cells undergo a unidirectional course of differentiation that progressively decreases the number of cell types they can potentially become. Pluripotent stem cells can differentiate into several types of cells, but terminally differentiated cells cannot differentiate any further. A fundamental problem in stem cell biology is the characterization of the difference in cellular states, e.g., gene expression profiles, between pluripotent stem cells and terminally differentiated cells. Presentation of the hypothesis To address the problem, we developed a dynamical systems model of cells with intracellular protein expression dynamics and interactions with each other. According to extensive simulations, cells with irregular (chaotic oscillations in gene expression dynamics have the potential to differentiate into other cell types. During development, such complex oscillations are lost successively, leading to a loss of pluripotency. These simulation results, together with recent single-cell-level measurements in stem cells, led us to the following hypothesis regarding pluripotency: Chaotic oscillation in the expression of some genes leads to cell pluripotency and affords cellular state heterogeneity, which is supported by itinerancy over quasi-stable states. Differentiation stabilizes these states, leading to a loss of pluripotency. Testing the hypothesis To test the hypothesis, it is crucial to measure the time course of gene expression levels at the single-cell level by fluorescence microscopy and fluorescence-activated cell sorting (FACS analysis. By analyzing the time series of single-cell-level expression data, one can distinguish whether the variation in protein expression level over time is due only to stochasticity in expression dynamics or originates from the chaotic dynamics inherent to cells, as our hypothesis predicts. By further analyzing the expression in differentiated cell types, one can examine whether the loss of pluripotency is accompanied by a loss of oscillation. Implications of the hypothesis Recovery of pluripotency from determined cells is a long-standing aspiration, from both scientific and clinical perspectives. Our hypothesis suggests a feasible route to recover the potential to differentiate, i.e., by increasing the variety of expressed genes to restore chaotic expression dynamics, as is consistent with the recent generation of induced pluripotent stem (iPS cells. Reviewers This article was reviewed by David Krakauer, Jeroen van Zon (nominated by Rob de Boer, and Williams S. Hlavacek.

  3. Quantum communication complexity advantage implies violation of a Bell inequality

    Science.gov (United States)

    Buhrman, Harry; Czekaj, Łukasz; Grudka, Andrzej; Horodecki, Michał; Horodecki, Paweł; Markiewicz, Marcin; Speelman, Florian; Strelchuk, Sergii

    2016-01-01

    We obtain a general connection between a large quantum advantage in communication complexity and Bell nonlocality. We show that given any protocol offering a sufficiently large quantum advantage in communication complexity, there exists a way of obtaining measurement statistics that violate some Bell inequality. Our main tool is port-based teleportation. If the gap between quantum and classical communication complexity can grow arbitrarily large, the ratio of the quantum value to the classical value of the Bell quantity becomes unbounded with the increase in the number of inputs and outputs. PMID:26957600

  4. Does boundary quantum mechanics imply quantum mechanics in the bulk?

    Science.gov (United States)

    Kabat, Daniel; Lifschytz, Gilad

    2018-03-01

    Perturbative bulk reconstruction in AdS/CFT starts by representing a free bulk field ϕ (0) as a smeared operator in the CFT. A series of 1 /N corrections must be added to ϕ (0) to represent an interacting bulk field ϕ. These corrections have been determined in the literature from several points of view. Here we develop a new perspective. We show that correlation functions involving ϕ (0) suffer from ambiguities due to analytic continuation. As a result ϕ (0) fails to be a well-defined linear operator in the CFT. This means bulk reconstruction can be understood as a procedure for building up well-defined operators in the CFT which thereby singles out the interacting field ϕ. We further propose that the difficulty with defining ϕ (0) as a linear operator can be re-interpreted as a breakdown of associativity. Presumably ϕ (0) can only be corrected to become an associative operator in perturbation theory. This suggests that quantum mechanics in the bulk is only valid in perturbation theory around a semiclassical bulk geometry.

  5. Implied Stopping Rules for American Basket Options from Markovian Projection

    KAUST Repository

    Bayer, Christian; Hä ppö lä , Juho; Tempone, Raul

    2017-01-01

    This work addresses the problem of pricing American basket options in a multivariate setting, which includes among others, the Bachelier and the Black-Scholes models. In high dimensions, nonlinear partial differential equation methods for solving the problem become prohibitively costly due to the curse of dimensionality. Instead, this work proposes to use a stopping rule that depends on the dynamics of a low-dimensional Markovian projection of the given basket of assets. It is shown that the ability to approximate the original value function by a lower-dimensional approximation is a feature of the dynamics of the system and is unaffected by the path-dependent nature of the American basket option. Assuming that we know the density of the forward process and using the Laplace approximation, we first efficiently evaluate the diffusion coefficient corresponding to the low-dimensional Markovian projection of the basket. Then, we approximate the optimal early-exercise boundary of the option by solving a Hamilton-Jacobi-Bellman partial differential equation in the projected, low-dimensional space. The resulting near-optimal early-exercise boundary is used to produce an exercise strategy for the high-dimensional option, thereby providing a lower bound for the price of the American basket option. A corresponding upper bound is also provided. These bounds allow to assess the accuracy of the proposed pricing method. Indeed, our approximate early-exercise strategy provides a straightforward lower bound for the American basket option price. Following a duality argument due to Rogers, we derive a corresponding upper bound solving only the low-dimensional optimal control problem. Numerically, we show the feasibility of the method using baskets with dimensions up to fifty. In these examples, the resulting option price relative errors are only of the order of few percent.

  6. Banal and Implied Forms of Violence in Levinas' Phenomenological Ethics

    Directory of Open Access Journals (Sweden)

    Fleurdeliz R. Altez

    2007-06-01

    Full Text Available Despite his final call for peace and "the wisdom of love", Emmanuel Levinas inevitably spoke of violence, and perhaps spoke even more of it. His call for infinite responsibility is actually crystallized through discourse on violence and suffering. We may say that these themes served as catalysts to the standing theory and, ethically, to any responsible Self. Violence, at least as a concept, poses itself as a significant presence to Levinas' plantilla while it reaches unexplored dimensions that await phenomenology and vital thought. As a part of his ethical proposal, understanding violence becomes important so that the Self may go beyond it while reaching the Other.

  7. Pattern overlap implies runaway growth in hierarchical tile systems

    Directory of Open Access Journals (Sweden)

    David Doty

    2015-11-01

    Full Text Available We show that in the hierarchical tile assembly model, if there is a producible assembly that overlaps a nontrivial translation of itself consistently (i.e., the pattern of tile types in the overlap region is identical in both translations, then arbitrarily large assemblies are producible. The significance of this result is that tile systems intended to controllably produce finite structures must avoid pattern repetition in their producible assemblies that would lead to such overlap.This answers an open question of Chen and Doty (SODA 2012, who showed that so-called "partial-order" systems producing a unique finite assembly and avoiding such overlaps must require time linear in the assembly diameter. An application of our main result is that any system producing a unique finite assembly is automatically guaranteed to avoid such overlaps, simplifying the hypothesis of Chen and Doty's main theorem.

  8. Spacelike penguin diagram effects in B implies PP decays

    International Nuclear Information System (INIS)

    Du, D.; Yang, M.; Zhang, D.

    1996-01-01

    The spacelike penguin diagram contributions to branching ratios and CP asymmetries in charmless decays of B to two pseudoscalar mesons are studied using the next-to-leading order low energy effective Hamiltonian. Both the gluonic penguin and the electroweak penguin diagrams are considered. We find that the effects are significant. copyright 1995 The American Physical Society

  9. Computer Simulations Imply Forelimb-Dominated Underwater Flight in Plesiosaurs.

    Directory of Open Access Journals (Sweden)

    Shiqiu Liu

    2015-12-01

    Full Text Available Plesiosaurians are an extinct group of highly derived Mesozoic marine reptiles with a global distribution that spans 135 million years from the Early Jurassic to the Late Cretaceous. During their long evolutionary history they maintained a unique body plan with two pairs of large wing-like flippers, but their locomotion has been a topic of debate for almost 200 years. Key areas of controversy have concerned the most efficient biologically possible limb stroke, e.g. whether it consisted of rowing, underwater flight, or modified underwater flight, and how the four limbs moved in relation to each other: did they move in or out of phase? Previous studies have investigated plesiosaur swimming using a variety of methods, including skeletal analysis, human swimmers, and robotics. We adopt a novel approach using a digital, three-dimensional, articulated, free-swimming plesiosaur in a simulated fluid. We generated a large number of simulations under various joint degrees of freedom to investigate how the locomotory repertoire changes under different parameters. Within the biologically possible range of limb motion, the simulated plesiosaur swims primarily with its forelimbs using an unmodified underwater flight stroke, essentially the same as turtles and penguins. In contrast, the hindlimbs provide relatively weak thrust in all simulations. We conclude that plesiosaurs were forelimb-dominated swimmers that used their hind limbs mainly for maneuverability and stability.

  10. Dark matter properties implied by gamma ray interstellar emission models

    Energy Technology Data Exchange (ETDEWEB)

    Balázs, Csaba; Li, Tong, E-mail: csaba.balazs@monash.edu, E-mail: tong.li@monash.edu [ARC Centre of Excellence for Particle Physics at the Tera-scale, School of Physics and Astronomy, Monash University, Melbourne, Victoria 3800 (Australia)

    2017-02-01

    We infer dark matter properties from gamma ray residuals extracted using eight different interstellar emission scenarios proposed by the Fermi-LAT Collaboration to explain the Galactic Center gamma ray excess. Adopting the most plausible simplified ansatz, we assume that the dark matter particle is a Majorana fermion interacting with standard fermions via a scalar mediator. To trivially respect flavor constraints, we only couple the mediator to third generation fermions. Using this theoretical hypothesis, and the Fermi residuals, we calculate Bayesian evidences, including Fermi-LAT exclusion limits from 15 dwarf spheroidal galaxies as well. Our evidence ratios single out one of the Fermi scenarios as most compatible with the simplified dark matter model. In this scenario the dark matter (mediator) mass is in the 25-200 (1-1000) GeV range and its annihilation is dominated by bottom quark final state. Our conclusion is that the properties of dark matter extracted from gamma ray data are highly sensitive to the modeling of the interstellar emission.

  11. Does Dual Ownership of Waste Imply a Regional Disposal Approach?

    International Nuclear Information System (INIS)

    Mele, I.

    2006-01-01

    The construction of the Nuclear Power Plant Krsko, being located in Slovenia near the Slovenian-Croatian border, was a joint investment by Slovenia and Croatia, two republics of the former Yugoslavia. The plant was completed in 1981 and the commercial operation started early in 1983. The obligations and rights of both investors during the construction and operation were specified in two bilateral contracts signed in 1974 and 1982. These contracts were fairly detailed on construction, operation and exploitation of the nuclear power plant (NPP), but they said very little about future nuclear liabilities. The electricity production was equally shared between the two countries and both parties participated in management of the NPP. In 1991, after Slovenia and Croatia became two independent countries, the agreement on the ownership and exploitation of the NPP Krsko was re-negotiated and a new contract signed in 2003. By the new contract the decommissioning and the disposal of spent fuel (SF) as well as low and intermediate level waste (LILW) is the responsibility of both parties, and the financial resources for covering these liabilities should be equally provided. Regardless of shared ownership of waste, the agreement opts for a single disposal solution for LILW as well as for SF, but the details are left open. More clear elaboration of these responsibilities is given in the programme of the decommissioning and disposal of radioactive waste from the NPP which was jointly prepared by the Slovenian and Croatian waste management organisations in 2004. The programme is clearly opting for only one repository for LILW and one repository for spent fuel, which can be located either in Slovenia or Croatia. Irrespective of the country where such a repository will be sited, dual ownership of waste opens up another dimension of such a solution: will such a repository be regarded as a national facility or as a regional or multinational facility? Both options-national and regional/multinational- may have a strong influence on future agreements on waste disposal, but so far these aspects have not been addressed either in Slovenia or Croatia. The paper brings reflections and discussion on these aspects of waste management in Slovenia and reveals the current situation of the waste disposal project in the country. (authors)

  12. Functional vs. Structural Modularity: do they imply each other?

    Science.gov (United States)

    Toroczkai, Zoltan

    2009-03-01

    While many deterministic and stochastic processes have been proposed to produce heterogeneous graphs mimicking real-world networks, only a handful of studies attempt to connect structure and dynamics with the function(s) performed by the network. In this talk I will present an approach built on the premise that structure, dynamics, and their observed heterogeneity, are implementations of various functions and their compositions. After a brief review of real-world networks where this connection can explicitly be made, I will focus on biological networks. Biological networks are known to possess functionally specialized modules, which perform tasks almost independently of each other. While proposals have been made for the evolutionary emergence of modularity, it is far from clear that adaptation on evolutionary timescales is the sole mechanism leading to functional specialization. We show that non-evolutionary learning can also lead to the formation of functionally specialized modules in a system exposed to multiple environmental constraints. A natural example suggesting that this is possible is the cerebral cortex, where there are clearly delineated functional areas in spite of the largely uniform anatomical construction of the cortical tissue. However, as numerous experiments show, when damaged, regions specialized for a certain function can be retrained to perform functions normally attributed to other regions. We use the paradigm of neural networks to represent a multitasking system, and use several non-evolutionary learning algorithms as mechanisms for phenotypic adaptation. We show that for a network learning to perform multiple tasks, the degree of independence between the tasks dictates the degree of functional specialization emerging in the network. To uncover the functional modules, we introduce a method of node knockouts that explicitly rates the contribution of each node to different tasks (differential robustness). Through a concrete example we also demonstrate the potential inability of purely topology-based clustering methods to detect functional modules. The robustness of these results suggests that similar mechanisms might be responsible for the emergence of functional specialization in other multitasking networks, as well, including social networks.

  13. INTRODUCTION Family planning implies the ability of individuals ...

    African Journals Online (AJOL)

    about 25% of women who have abortion in Nigeria ... Keywords: Family planning, awareness, pregnant women, Nigeria. Annals of Ibadan .... Washington D.C. World bank 1987;52. 6. ... 2007;1(1) : Accessed on line on 7th March,2008. 19.

  14. Implied...or implode? The Simpsons' carnivalesque Treehouse of Horror

    OpenAIRE

    Jones, Steve

    2010-01-01

    Since 1990, The Simpsons’ annual “Treehouse of Horror” episodes have constituted a production sub-context within the series, having their own conventions and historical trajectory. These specials incorporate horror plots and devices, as well as general references to science fiction, into the series’ base in situation comedy. The Halloween specials disrupt the series usual family-oriented sitcom structure, dissolving the ideological balances that stabilise that society. By depicting the Family...

  15. Quantum communication complexity advantage implies violation of a Bell inequality

    NARCIS (Netherlands)

    H. Buhrman (Harry); L. Czekaj (Lłukasz); A. Grudka (Andrzej); M. Horodecki (Michalł); P. Horodecki (Pawelł); M. Markiewicz (Marcin); F. Speelman (Florian); S. Strelchuk (Sergii)

    2015-01-01

    htmlabstractWe obtain a general connection between a quantum advantage in communication complexity and non-locality. We show that given any protocol offering a (sufficiently large) quantum advantage in communication complexity, there exists a way of obtaining measurement statistics which violate

  16. Generic antibiotic industries: Challenges and implied strategies with regulatory perspectives

    Directory of Open Access Journals (Sweden)

    M Venkatesh

    2011-01-01

    Full Text Available Ever since the discovery of antibiotics, the quality of human life greatly improved in the 20 th century. The discovery of penicillin transformed the medicine industry and initiated a search for a better antibiotic every time resulting in several synthetic and semi-synthetic antibiotics. Beginning with the 1937 sulfa drug tragedy, the drug regulations had a parallel growth along with the antibiotics and the antibiotic-based generic Pharma industries. This review article is focused on the scenario depicting current global Pharma industries based on generic antibiotics. Several regulatory aspects involved with these industries have been discussed along with the complexity of the market, issues that could affect their growth, their struggle for quality, and their compliance with the tightened regulations. With the skyrocketing commercialization of antibiotics through generics and the leveraging technologic renaissance, generic industries are involved in providing maximum safer benefits for the welfare of the people, highlighting its need today.

  17. Does implied community size predict likeability of a similar stranger?

    Science.gov (United States)

    Launay, Jacques; Dunbar, Robin I M

    2015-01-01

    Homophily, the tendency for people to cluster with similar others, has primarily been studied in terms of proximal, psychological causes, such as a tendency to have positive associations with people who share traits with us. Here we investigate whether homophily could be correlated with perceived group membership, given that sharing traits with other people might signify membership of a specific community. In order to investigate this, we tested whether the amount of homophily that occurs between strangers is dependent on the number of people they believe share the common trait (i.e. the size of group that the trait identifies). In two experiments, we show that more exclusive (smaller) groups evoke more positive ratings of the likeability of a stranger. When groups appear to be too inclusive (i.e. large) homophily no longer occurs, suggesting that it is not only positive associations with a trait that cause homophily, but a sense of the exclusiveness of a group is also important. These results suggest that group membership based on a variety of traits can encourage cohesion between people from diverse backgrounds, and may be a useful tool in overcoming differences between groups.

  18. Experimental signature of scaling violation implied by field theories

    International Nuclear Information System (INIS)

    Tung, W.

    1975-01-01

    Renormalizable field theories are found to predict a surprisingly specific pattern of scaling violation in deep inelastic scattering. Comparison with experiments is discussed. The feasibility of distinguishing asymptotically free field theories from conventional field theories is evaluated

  19. Modeling of CPDOs - Identifying Optimal and Implied Leverage

    DEFF Research Database (Denmark)

    Dorn, Jochen

    When the subprime crisis started emerging, collateralized products based on Credit Default Swap (CDS) exposures combined with security features seemed to be a more rational alternative to classic asset backed securities. Constant Proportion Collateralized Debt Obligations (CPDOs) are a mixture...... of Collateralized Debt Obligations (CDOs) and CPPIs with inverse mechanism. This new asset targets to meet the investors' demand for credit derivatives with security enhancements, but quantitative approaches for pricing except for simulation algorithms do not exist yet up to he author's knowledge. CPDOs became...... risks and provides a dynamic closed-form pricing formula....

  20. Implied Dynamics Biases the Visual Perception of Velocity

    Science.gov (United States)

    La Scaleia, Barbara; Zago, Myrka; Moscatelli, Alessandro; Lacquaniti, Francesco; Viviani, Paolo

    2014-01-01

    We expand the anecdotic report by Johansson that back-and-forth linear harmonic motions appear uniform. Six experiments explore the role of shape and spatial orientation of the trajectory of a point-light target in the perceptual judgment of uniform motion. In Experiment 1, the target oscillated back-and-forth along a circular arc around an invisible pivot. The imaginary segment from the pivot to the midpoint of the trajectory could be oriented vertically downward (consistent with an upright pendulum), horizontally leftward, or vertically upward (upside-down). In Experiments 2 to 5, the target moved uni-directionally. The effect of suppressing the alternation of movement directions was tested with curvilinear (Experiment 2 and 3) or rectilinear (Experiment 4 and 5) paths. Experiment 6 replicated the upright condition of Experiment 1, but participants were asked to hold the gaze on a fixation point. When some features of the trajectory evoked the motion of either a simple pendulum or a mass-spring system, observers identified as uniform the kinematic profiles close to harmonic motion. The bias towards harmonic motion was most consistent in the upright orientation of Experiment 1 and 6. The bias disappeared when the stimuli were incompatible with both pendulum and mass-spring models (Experiments 3 to 5). The results are compatible with the hypothesis that the perception of dynamic stimuli is biased by the laws of motion obeyed by natural events, so that only natural motions appear uniform. PMID:24667578

  1. Implied dynamics biases the visual perception of velocity.

    Directory of Open Access Journals (Sweden)

    Barbara La Scaleia

    Full Text Available We expand the anecdotic report by Johansson that back-and-forth linear harmonic motions appear uniform. Six experiments explore the role of shape and spatial orientation of the trajectory of a point-light target in the perceptual judgment of uniform motion. In Experiment 1, the target oscillated back-and-forth along a circular arc around an invisible pivot. The imaginary segment from the pivot to the midpoint of the trajectory could be oriented vertically downward (consistent with an upright pendulum, horizontally leftward, or vertically upward (upside-down. In Experiments 2 to 5, the target moved uni-directionally. The effect of suppressing the alternation of movement directions was tested with curvilinear (Experiment 2 and 3 or rectilinear (Experiment 4 and 5 paths. Experiment 6 replicated the upright condition of Experiment 1, but participants were asked to hold the gaze on a fixation point. When some features of the trajectory evoked the motion of either a simple pendulum or a mass-spring system, observers identified as uniform the kinematic profiles close to harmonic motion. The bias towards harmonic motion was most consistent in the upright orientation of Experiment 1 and 6. The bias disappeared when the stimuli were incompatible with both pendulum and mass-spring models (Experiments 3 to 5. The results are compatible with the hypothesis that the perception of dynamic stimuli is biased by the laws of motion obeyed by natural events, so that only natural motions appear uniform.

  2. Implied dynamics biases the visual perception of velocity.

    Science.gov (United States)

    La Scaleia, Barbara; Zago, Myrka; Moscatelli, Alessandro; Lacquaniti, Francesco; Viviani, Paolo

    2014-01-01

    We expand the anecdotic report by Johansson that back-and-forth linear harmonic motions appear uniform. Six experiments explore the role of shape and spatial orientation of the trajectory of a point-light target in the perceptual judgment of uniform motion. In Experiment 1, the target oscillated back-and-forth along a circular arc around an invisible pivot. The imaginary segment from the pivot to the midpoint of the trajectory could be oriented vertically downward (consistent with an upright pendulum), horizontally leftward, or vertically upward (upside-down). In Experiments 2 to 5, the target moved uni-directionally. The effect of suppressing the alternation of movement directions was tested with curvilinear (Experiment 2 and 3) or rectilinear (Experiment 4 and 5) paths. Experiment 6 replicated the upright condition of Experiment 1, but participants were asked to hold the gaze on a fixation point. When some features of the trajectory evoked the motion of either a simple pendulum or a mass-spring system, observers identified as uniform the kinematic profiles close to harmonic motion. The bias towards harmonic motion was most consistent in the upright orientation of Experiment 1 and 6. The bias disappeared when the stimuli were incompatible with both pendulum and mass-spring models (Experiments 3 to 5). The results are compatible with the hypothesis that the perception of dynamic stimuli is biased by the laws of motion obeyed by natural events, so that only natural motions appear uniform.

  3. Maslow's Implied Matrix: A Clarification of the Need Hierarchy Theory.

    Science.gov (United States)

    Marsh, Edward

    1978-01-01

    Maslow's need hierarchy theory is restated by means of a matrix arrangement of the constructs within the theory. After consideration of the consequences of this restatement, some significant research is discussed and directions for future research suggested. (Author)

  4. Generic antibiotic industries: Challenges and implied strategies with regulatory perspectives

    Science.gov (United States)

    Venkatesh, M.; Bairavi, V. G.; Sasikumar, K. C.

    2011-01-01

    Ever since the discovery of antibiotics, the quality of human life greatly improved in the 20th century. The discovery of penicillin transformed the medicine industry and initiated a search for a better antibiotic every time resulting in several synthetic and semi-synthetic antibiotics. Beginning with the 1937 sulfa drug tragedy, the drug regulations had a parallel growth along with the antibiotics and the antibiotic-based generic Pharma industries. This review article is focused on the scenario depicting current global Pharma industries based on generic antibiotics. Several regulatory aspects involved with these industries have been discussed along with the complexity of the market, issues that could affect their growth, their struggle for quality, and their compliance with the tightened regulations. With the skyrocketing commercialization of antibiotics through generics and the leveraging technologic renaissance, generic industries are involved in providing maximum safer benefits for the welfare of the people, highlighting its need today.. PMID:21430959

  5. The implied producer investigating an emergent typology in participatory culture

    DEFF Research Database (Denmark)

    Søndergaard, Morten

    2012-01-01

    Biennales, that we are not 'just' dealing with a 'new' genre or style within the art category; on the other hand we are not dealing with a pure commercial culture either (the abstract notion of 'the user' has its limits); what is becoming evident is that the 'implicit' roles of the participatory 'actors...

  6. Implied Stopping Rules for American Basket Options from Markovian Projection

    KAUST Repository

    Bayer, Christian

    2017-05-01

    This work addresses the problem of pricing American basket options in a multivariate setting, which includes among others, the Bachelier and the Black-Scholes models. In high dimensions, nonlinear partial differential equation methods for solving the problem become prohibitively costly due to the curse of dimensionality. Instead, this work proposes to use a stopping rule that depends on the dynamics of a low-dimensional Markovian projection of the given basket of assets. It is shown that the ability to approximate the original value function by a lower-dimensional approximation is a feature of the dynamics of the system and is unaffected by the path-dependent nature of the American basket option. Assuming that we know the density of the forward process and using the Laplace approximation, we first efficiently evaluate the diffusion coefficient corresponding to the low-dimensional Markovian projection of the basket. Then, we approximate the optimal early-exercise boundary of the option by solving a Hamilton-Jacobi-Bellman partial differential equation in the projected, low-dimensional space. The resulting near-optimal early-exercise boundary is used to produce an exercise strategy for the high-dimensional option, thereby providing a lower bound for the price of the American basket option. A corresponding upper bound is also provided. These bounds allow to assess the accuracy of the proposed pricing method. Indeed, our approximate early-exercise strategy provides a straightforward lower bound for the American basket option price. Following a duality argument due to Rogers, we derive a corresponding upper bound solving only the low-dimensional optimal control problem. Numerically, we show the feasibility of the method using baskets with dimensions up to fifty. In these examples, the resulting option price relative errors are only of the order of few percent.

  7. On cosmic censorship: do compact Cauchy horizons imply symmetry?

    International Nuclear Information System (INIS)

    Isenberg, J.; Moncrief, V.

    1983-01-01

    The basic idea of Cosmic Censorship is that, in a physically reasonable spacetime, an observer should not encounter any naked singularities. The authors discuss some new results which provide strong support for one of the statements of Cosmic Censorship: Strong Cosmic Censorship says that the maximal spacetime development of a set of Cauchy data on a spacelike initial surface (evolved via the vacuum Einstein equations, the Einstein-Maxwell equations, or some other 'reasonable' set) will not be extendible across a Cauchy horizon. (Auth.)

  8. Hubble's Law Implies Benford's Law for Distances to Galaxies ...

    Indian Academy of Sciences (India)

    in both time and space, predicts that conformity to Benford's law will improve as more data on distances to galaxies becomes available. Con- versely, with the logical derivation of this law presented here, the recent empirical observations may beviewed as independent evidence of the validity of Hubble's law. Key words.

  9. Implied motion language can influence visual spatial memory

    NARCIS (Netherlands)

    Vinson, David; Engelen, Jan; Zwaan, Rolf A; Matlock, Teenie; Dale, Rick

    How do language and vision interact? Specifically, what impact can language have on visual processing, especially related to spatial memory? What are typically considered errors in visual processing, such as remembering the location of an object to be farther along its motion trajectory than it

  10. Drunk driving, implied consent, and self-incrimination.

    Science.gov (United States)

    Ogundipe, Kehinde A; Weiss, Kenneth J

    2009-01-01

    The effects of drunk driving are a significant risk to public health and safety. Accordingly, the federal government and the states have enacted laws that permit law enforcement to identify offenders and to apply various levels of sanctions. There is no constitutional requirement that evidence of drunkenness be permitted in defense of criminal behavior. In practice, citizens who undertake to operate motor vehicles under the influence of alcohol are considered reckless per se and have no right to obstruct law enforcement in determining their condition. Indeed, refusal of roadside sobriety tests, including the Breathalyzer, may be considered a separate offense. The issuing of Miranda-type warnings by police officers has been ruled on recently in New Jersey. In a superior court appellate decision, State v. Spell, the court outlined the necessary procedures, concluding that, although motorists have no right to refuse testing, police officers have an obligation to issue sufficient warnings before the motorist decides how to proceed. In the Spell matter, the defendant incriminated himself by refusing the testing, even though he was acquitted on the drunk-driving charge. The authors discuss the role of expert testimony in these matters.

  11. Finite Correlation Length Implies Efficient Preparation of Quantum Thermal States

    Science.gov (United States)

    Brandão, Fernando G. S. L.; Kastoryano, Michael J.

    2018-05-01

    Preparing quantum thermal states on a quantum computer is in general a difficult task. We provide a procedure to prepare a thermal state on a quantum computer with a logarithmic depth circuit of local quantum channels assuming that the thermal state correlations satisfy the following two properties: (i) the correlations between two regions are exponentially decaying in the distance between the regions, and (ii) the thermal state is an approximate Markov state for shielded regions. We require both properties to hold for the thermal state of the Hamiltonian on any induced subgraph of the original lattice. Assumption (ii) is satisfied for all commuting Gibbs states, while assumption (i) is satisfied for every model above a critical temperature. Both assumptions are satisfied in one spatial dimension. Moreover, both assumptions are expected to hold above the thermal phase transition for models without any topological order at finite temperature. As a building block, we show that exponential decay of correlation (for thermal states of Hamiltonians on all induced subgraphs) is sufficient to efficiently estimate the expectation value of a local observable. Our proof uses quantum belief propagation, a recent strengthening of strong sub-additivity, and naturally breaks down for states with topological order.

  12. When I cut, you choose method implies intransitivity

    Science.gov (United States)

    Makowski, Marcin; Piotrowski, Edward W.

    2014-12-01

    There is a common belief that humans and many animals follow transitive inference (choosing A over C on the basis of knowing that A is better than B and B is better than C). Transitivity seems to be the essence of rational choice. We present a theoretical model of a repeated game in which the players make a choice between three goods (e.g. food). The rules of the game refer to the simple procedure of fair division among two players, known as the “I cut, you choose” mechanism which has been widely discussed in the literature. In this game one of the players has to make intransitive choices in order to achieve the optimal result (for him/her and his/her co-player). The point is that an intransitive choice can be rational. Previously, an increase in the significance of intransitive strategies was achieved by referring to models of quantum games. We show that relevant intransitive strategies also appear in the classic description of decision algorithms.

  13. Implied Volatility and Rebalancing Timing: Market cycles and the relationship between implied volatility indices and stock index returns.

    OpenAIRE

    Holst, Niklas; Rønning, Harald

    2017-01-01

    Master's thesis in Finance This paper studies market timing based upon the level of the VIX and compares VIX based portfolio rotations with modern rebalancing practices. The thesis analyses the outcomes of the different rebalancing and trading strategies, and compare them through different performance measures. The study finds that on average, rebalancing strategies based on the level of the VIX does not have significant positive returns compared to the standard dynamic rebalancing scheme ...

  14. DESYNC: Self-Organizing Desynchronization and TDMA on Wireless Sensor Networks

    OpenAIRE

    Degesys, Julius; Rose, Ian; Patel, Ankit; Nagpal, Radhika

    2006-01-01

    Desynchronization is a novel primitive for sensor networks: it implies that nodes perfectly interleave periodic events to occur in a round-robin schedule. This primitive can be used to evenly distribute sampling burden in a group of nodes, schedule sleep cycles, or organize a collision-free TDMA schedule for transmitting wireless messages. Here we present Desync, a biologically-inspired self-maintaining algorithm for desynchronization in a single-hop network. We present (1) theoretical result...

  15. Conception of one through the implied sense of Philosophy, Sociology, Psychoanalisis and Logotherapy

    Directory of Open Access Journals (Sweden)

    Carlos Eduardo Freitas

    2015-10-01

    Full Text Available The main goal of this current article is identifying the conception of the one in the disciplines of philosophy, sociology, psychoanalisis and logotherapy; in the perspective of the subject’s objective choice. In order to accomplish the study of such conceptions, one and its choice, besides the specialists from each discipline already mentioned, distinct author’s conceptions have also been considered. Their overlay contributes to a better understanding of current interests concerning the process of choice by each person, as well as the basic principles which lead one. As result, the standpoint that leads one to choose an object, isn’t necessarily identical to the objective importance that the object has itself: an object of choice such as vocation, may be not only a value itself, but also chosen by deeply personal reasons and interests.

  16. The effect of non-financial risk information on the evaluation of implied cost of capitals

    OpenAIRE

    Norio Kitagawa; Hyonok Kim; Masatoshi Goto

    2011-01-01

    The purpose of this paper is to examine the effect of voluntary disclosure of `business risk' information (hereafter referred to as `risk information' ), which is a significant determinant of the information environment, on estimating the cost of capital. Recently, some studies indicate that the reliability of the cost of capital estimation differs according to the accounting standards and the information environment of the firm (e.g. Chen et al., 2004; Easton and Monahan, 2005). On the basis...

  17. Genome comparison implies the role of Wsm2 in membrane trafficking and protein degradation

    Directory of Open Access Journals (Sweden)

    Guorong Zhang

    2018-04-01

    Full Text Available Wheat streak mosaic virus (WSMV causes streak mosaic disease in wheat (Triticum aestivum L. and has been an important constraint limiting wheat production in many regions around the world. Wsm2 is the only resistance gene discovered in wheat genome and has been located in a short genomic region of its chromosome 3B. However, the sequence nature and the biological function of Wsm2 remain unknown due to the difficulty of genetic manipulation in wheat. In this study, we tested WSMV infectivity among wheat and its two closely related grass species, rice (Oryza sativa and Brachypodium distachyon. Based on the phenotypic result and previous genomic studies, we developed a novel bioinformatics pipeline for interpreting a potential biological function of Wsm2 and its ancestor locus in wheat. In the WSMV resistance tests, we found that rice has a WMSV resistance gene while Brachypodium does not, which allowed us to hypothesize the presence of a Wsm2 ortholog in rice. Our OrthoMCL analysis of protein coding genes on wheat chromosome 3B and its syntenic chromosomes in rice and Brachypodium discovered 4,035 OrthoMCL groups as preliminary candidates of Wsm2 orthologs. Given that Wsm2 is likely duplicated through an intrachromosomal illegitimate recombination and that Wsm2 is dominant, we inferred that this new WSMV-resistance gene acquired an activation domain, lost an inhibition domain, or gained high expression compared to its ancestor locus. Through comparison, we identified that 67, 16, and 10 out of 4,035 OrthoMCL orthologous groups contain a rice member with 25% shorter or longer in length, or 10 fold more expression, respectively, than those from wheat and Brachypodium. Taken together, we predicted a total of 93 good candidates for a Wsm2 ancestor locus. All of these 93 candidates are not tightly linked with Wsm2, indicative of the role of illegitimate recombination in the birth of Wsm2. Further sequence analysis suggests that the protein products of Wsm2 may combat WSMV disease through a molecular mechanism involving protein degradation and/or membrane trafficking. The 93 putative Wsm2 ancestor loci discovered in this study could serve as good candidates for future genetic isolation of the true Wsm2 locus.

  18. Fast computation of vanilla prices in time-changed models and implied volatilities using rational approximations

    NARCIS (Netherlands)

    Pistorius, M.; Stolte, J.

    2012-01-01

    We present a new numerical method to price vanilla options quickly in time-changed Brownian motion models. The method is based on rational function approximations of the Black-Scholes formula. Detailed numerical results are given for a number of widely used models. In particular, we use the

  19. Unidimensional factor models imply weaker partial correlations than zero-order correlations.

    Science.gov (United States)

    van Bork, Riet; Grasman, Raoul P P P; Waldorp, Lourens J

    2018-06-01

    In this paper we present a new implication of the unidimensional factor model. We prove that the partial correlation between two observed variables that load on one factor given any subset of other observed variables that load on this factor lies between zero and the zero-order correlation between these two observed variables. We implement this result in an empirical bootstrap test that rejects the unidimensional factor model when partial correlations are identified that are either stronger than the zero-order correlation or have a different sign than the zero-order correlation. We demonstrate the use of the test in an empirical data example with data consisting of fourteen items that measure extraversion.

  20. Disintegration of collagen fibrils by Glucono-δ-lactone: An implied lead for disintegration of fibrosis.

    Science.gov (United States)

    Jayamani, Jayaraman; Ravikanth Reddy, R; Madhan, Balaraman; Shanmugam, Ganesh

    2018-02-01

    Excess accumulation of collagen (fibrosis) undergoes self-aggregation, which leads to fibrillar collagen, on the extracellular matrix is the hallmark of a number of diseases such as keloids, hypertrophic scars, and systemic scleroderma. Direct inhibition or disintegration of collagen fibrils by small molecules offer a therapeutic approach to prevent or treat the diseases related to fibrosis. Herein, the anti-fibrotic property of Glucono-δ-lactone (GdL), known as acidifier, on the fibrillation and its disintegration of collagen was investigated. As collagen fibrillation is pH dependent, the pH modulation property of GdL is attractive to inhibit self-association of collagen. Optical density and microscopic data indicate that GdL elicits concentration-dependent fibril inhibition and also disintegrates pre-formed collagen fibrils. The simultaneous pH analysis showed that the modulation(lowering) of pH by GdL is the primary cause for its anti-fibrotic activity. The intact triple helical structure of collagen upon treatment of GdL suggests that collagen fibril disintegration can be achieved without affecting the native structure of collagen which is essential for any anti-fibrotic agents. Saturation transfer difference (STD) NMR result reveals that GdL is in proximity to collagen. The present results thus suggest that GdL provides a lead to design novel anti-fibrotic agents for the pathologies related to collagen deposition. Copyright © 2017 Elsevier B.V. All rights reserved.

  1. Observed forest sensitivity to climate implies large changes in 21st century North American forest growth.

    Science.gov (United States)

    Charney, Noah D; Babst, Flurin; Poulter, Benjamin; Record, Sydne; Trouet, Valerie M; Frank, David; Enquist, Brian J; Evans, Margaret E K

    2016-09-01

    Predicting long-term trends in forest growth requires accurate characterisation of how the relationship between forest productivity and climatic stress varies across climatic regimes. Using a network of over two million tree-ring observations spanning North America and a space-for-time substitution methodology, we forecast climate impacts on future forest growth. We explored differing scenarios of increased water-use efficiency (WUE) due to CO2 -fertilisation, which we simulated as increased effective precipitation. In our forecasts: (1) climate change negatively impacted forest growth rates in the interior west and positively impacted forest growth along the western, southeastern and northeastern coasts; (2) shifting climate sensitivities offset positive effects of warming on high-latitude forests, leaving no evidence for continued 'boreal greening'; and (3) it took a 72% WUE enhancement to compensate for continentally averaged growth declines under RCP 8.5. Our results highlight the importance of locally adapted forest management strategies to handle regional differences in growth responses to climate change. © 2016 John Wiley & Sons Ltd/CNRS.

  2. Fossil diatoms imply common cometary origin of space-dust and the Polonnaruwa meteorite

    Science.gov (United States)

    Miyake, N.; Wallis, M. K.; Wickramasinghe, N. C.

    2013-09-01

    IDPs collected in 2001 at 40km altitude by cryosamplers studied via scanning electron microscopy and EDX were found to contain siliceous fibres and whiskers, some isolated but often embedded in a mineral matrix. The newly-arrived Polonnaruwa meteorite gives strong evidence for the hypothesis that they are fragments of diatoms agglomerating on solar system icy bodies. Diatom frustules and even whole diatom skeletons are identifiable within the meteorite. Specimens of a siliceous exoskeleton with multiple spines/whiskers have also been found, thought to be freshwater diatoms. As diatoms are dependent on a source of nitrogenous organics, the siliceous whiskers within IDPs would be an indicator of a photosynthesizing ecosystem, probably on a comet.

  3. Density Forecasts of Crude-Oil Prices Using Option-Implied and ARCH-Type Models

    DEFF Research Database (Denmark)

    Tsiaras, Leonidas; Høg, Esben

      The predictive accuracy of competing crude-oil price forecast densities is investigated for the 1994-2006 period. Moving beyond standard ARCH models that rely exclusively on past returns, we examine the benefits of utilizing the forward-looking information that is embedded in the prices...... as for regions and intervals that are of special interest for the economic agent. We find that non-parametric adjustments of risk-neutral density forecasts perform significantly better than their parametric counterparts. Goodness-of-fit tests and out-of-sample likelihood comparisons favor forecast densities...

  4. Observations of oxidation products above a forest imply biogenic emissions of very reactive compounds

    Directory of Open Access Journals (Sweden)

    R. Holzinger

    2005-01-01

    Full Text Available Vertical gradients of mixing ratios of volatile organic compounds have been measured in a Ponderosa pine forest in Central California (38.90° N, 120.63° W, 1315m. These measurements reveal large quantities of previously unreported oxidation products of short lived biogenic precursors. The emission of biogenic precursors must be in the range of 13-66µmol m-2h-1 to produce the observed oxidation products. That is 6-30 times the emissions of total monoterpenes observed above the forest canopy on a molar basis. These reactive precursors constitute a large fraction of biogenic emissions at this site, and are not included in current emission inventories. When oxidized by ozone they should efficiently produce secondary aerosol and hydroxyl radicals.

  5. The quarter-power scaling model does not imply size-invariant hydraulic resistance in plants

    Science.gov (United States)

    Annikki Makela; Harry T. Valentine

    2006-01-01

    West, Brown, and Enquist (1997, 1999) propose an integrated model of the structure and allometry of plant vascular systems, which has come to be known as the 'WBE model' (Enquist, 2002). The WBE model weaves together area-preserving branching (Leonardo da Vinci), elastic similarity (Greenhill, 1881), the constant ratio of foliage mass to sapwood area (...

  6. 77 FR 2975 - Roosevelt Water Conservation District; Notice of Termination of Exemption by Implied Surrender...

    Science.gov (United States)

    2012-01-20

    .... Project No.: 11572-001. c. Date Initiated: January 9, 2012. d. Exemptee: Roosevelt Water Conservation District. e. Name and Location of Project: The Roosevelt Water Conservation District Conduit Hydropower..., Roosevelt Water Conservation District, 2344 S. Higley Road, Gilbert, AZ 82595-4794, (480) 988-9586. [[Page...

  7. Interstrand cross-linking implies contrasting structural consequences for DNA: insights from molecular dynamics

    Czech Academy of Sciences Publication Activity Database

    Bignon, E.; Dršata, Tomáš; Morell, C.; Lankaš, Filip; Dumont, E.

    2017-01-01

    Roč. 45, č. 4 (2017), s. 2188-2195 ISSN 0305-1048 R&D Projects: GA ČR(CZ) GA14-21893S Institutional support: RVO:61388963 Keywords : abasic sites * duplex DNA * mechanical properties Subject RIV: BO - Biophysics OBOR OECD: Biophysics Impact factor: 10.162, year: 2016 https://academic.oup.com/nar/article-lookup/doi/10.1093/nar/gkw1253

  8. Discovery of rapid whistlers close to Jupiter implying lightning rates similar to those on Earth

    Science.gov (United States)

    Kolmašová, Ivana; Imai, Masafumi; Santolík, Ondřej; Kurth, William S.; Hospodarsky, George B.; Gurnett, Donald A.; Connerney, John E. P.; Bolton, Scott J.

    2018-06-01

    Electrical currents in atmospheric lightning strokes generate impulsive radio waves in a broad range of frequencies, called atmospherics. These waves can be modified by their passage through the plasma environment of a planet into the form of dispersed whistlers1. In the Io plasma torus around Jupiter, Voyager 1 detected whistlers as several-seconds-long slowly falling tones at audible frequencies2. These measurements were the first evidence of lightning at Jupiter. Subsequently, Jovian lightning was observed by optical cameras on board several spacecraft in the form of localized flashes of light3-7. Here, we show measurements by the Waves instrument8 on board the Juno spacecraft9-11 that indicate observations of Jovian rapid whistlers: a form of dispersed atmospherics at extremely short timescales of several milliseconds to several tens of milliseconds. On the basis of these measurements, we report over 1,600 lightning detections, the largest set obtained to date. The data were acquired during close approaches to Jupiter between August 2016 and September 2017, at radial distances below 5 Jovian radii. We detected up to four lightning strokes per second, similar to rates in thunderstorms on Earth12 and six times the peak rates from the Voyager 1 observations13.

  9. Large arteriolar component of oxygen delivery implies a safe margin of oxygen supply to cerebral tissue.

    Science.gov (United States)

    Sakadžić, Sava; Mandeville, Emiri T; Gagnon, Louis; Musacchia, Joseph J; Yaseen, Mohammad A; Yucel, Meryem A; Lefebvre, Joel; Lesage, Frédéric; Dale, Anders M; Eikermann-Haerter, Katharina; Ayata, Cenk; Srinivasan, Vivek J; Lo, Eng H; Devor, Anna; Boas, David A

    2014-12-08

    What is the organization of cerebral microvascular oxygenation and morphology that allows adequate tissue oxygenation at different activity levels? We address this question in the mouse cerebral cortex using microscopic imaging of intravascular O2 partial pressure and blood flow combined with numerical modelling. Here we show that parenchymal arterioles are responsible for 50% of the extracted O2 at baseline activity, and the majority of the remaining O2 exchange takes place within the first few capillary branches. Most capillaries release little O2 at baseline acting as an O2 reserve that is recruited during increased neuronal activity or decreased blood flow. Our results challenge the common perception that capillaries are the major site of O2 delivery to cerebral tissue. The understanding of oxygenation distribution along arterio-capillary paths may have profound implications for the interpretation of blood-oxygen-level dependent (BOLD) contrast in functional magnetic resonance imaging and for evaluating microvascular O2 delivery capacity to support cerebral tissue in disease.

  10. Small-scale microwave background anisotropies implied by large-scale data

    Science.gov (United States)

    Kashlinsky, A.

    1993-01-01

    In the absence of reheating microwave background radiation (MBR) anisotropies on arcminute scales depend uniquely on the amplitude and the coherence length of the primordial density fluctuations (PDFs). These can be determined from the recent data on galaxy correlations, xi(r), on linear scales (APM survey). We develop here expressions for the MBR angular correlation function, C(theta), on arcminute scales in terms of the power spectrum of PDFs and demonstrate their accuracy by comparing with detailed calculations of MBR anisotropies. We then show how to evaluate C(theta) directly in terms of the observed xi(r) and show that the APM data give information on the amplitude, C(O), and the coherence angle of MBR anisotropies on small scales.

  11. Shapes of Venusian 'pancake' domes imply episodic emplacement and silicic composition

    Science.gov (United States)

    Fink, Jonathan H.; Bridges, Nathan T.; Grimm, Robert E.

    1993-01-01

    The main evidence available for constraining the composition of the large circular 'pancake' domes on Venus is their gross morphology. Laboratory simulations using polyethylene glycol show that the height to diameter (aspect) ratios of domes of a given total volume depend critically on whether their extrusion was continuous or episodic, with more episodes leading to greater cooling and taller domes. Thus without observations of their emplacement, the compositions of Venusian domes cannot be uniquely constrained by their morphology. However, by considering a population of 51 Venusian domes to represent a sampling of many stages during the growth of domes with comparable histories, and by plotting aspect ratio versus total volume, we find that the shapes of the domes are most consistent with episodic emplacement. On Earth this mode of dome growth is found almost exclusively in lavas of dacite to rhyolite composition, strengthening earlier inferences about the presence of evolved magmas on Venus.

  12. The cross-national pattern of happiness. Test of predictions implied in three theories of happiness

    NARCIS (Netherlands)

    R. Veenhoven (Ruut); J.J. Ehrhardt (Joop)

    1995-01-01

    textabstractABSTRACT. Predictions about level and dispersion of happiness in nations are derived from three theories of happiness: comparison-theory, folklore-theory and livability-theory. The predictions are tested on two cross national data-sets: a comparative survey among university students in

  13. Experimental heat treatment of silcrete implies analogical reasoning in the Middle Stone Age.

    Science.gov (United States)

    Wadley, Lyn; Prinsloo, Linda C

    2014-05-01

    Siliceous rocks that were not heated to high temperatures during their geological formation display improved knapping qualities when they are subjected to controlled heating. Experimental heat treatment of South African silcrete, using open fires of the kind used during the Middle Stone Age, shows that the process needed careful management, notwithstanding recent arguments to the contrary. Silcrete blocks fractured when heated on the surface of open fires or on coal beds, but were heated without mishap when buried in sand below a fire. Three silcrete samples, a control, a block heated underground with maximum temperature between 400 and 500 °C and a block heated in an open fire with maximum temperature between 700 and 800 °C, were analysed with X-ray powder diffraction (XRD), X-ray fluorescence (XRF), optical microscopy, and both Fourier transform infrared (FTIR) and Raman spectroscopy. The results show that the volume expansion during the thermally induced α- to β-quartz phase transformation and the volume contraction during cooling play a major role in the heat treatment of silcrete. Rapid heating or cooling through the phase transformation at 573 °C will cause fracture of the silcrete. Successful heat treatment requires controlling surface fire temperatures in order to obtain the appropriate underground temperatures to stay below the quartz inversion temperature. Heat treatment of rocks is a transformative technology that requires skilled use of fire. This process involves analogical reasoning, which is an attribute of complex cognition. Copyright © 2014 Elsevier Ltd. All rights reserved.

  14. When Culture Implies Deficit: Placing Race at the Center of Hmong American Education

    Science.gov (United States)

    DePouw, Christin

    2012-01-01

    There is a need for a critical race analysis of Hmong American education that places race and racism at the center of analysis, highlights Whiteness as property and recognizes the fluid and situated racialization of Hmong American students. Majoritarian explanations of inequities in Hmong American education often describe Hmong American student…

  15. 76 FR 63294 - River Bounty, Inc.; Notice of Termination of Exemption By Implied Surrender and Soliciting...

    Science.gov (United States)

    2011-10-12

    ... powerhouse containing three units. Currently, there is a 50- to 60-foot-wide breach in the dam. The project... the Oakland Project because it lost its power sales contract. Since that time, the powerhouse..., the breach expanded leaving a 50- to 60-foot- wide opening in the dam. In April 2011, the Commission...

  16. Sakurai Prize: Why the Higgs Boson data implies an M-theory world

    Science.gov (United States)

    Kane, Gordon

    2017-01-01

    Compactifying 11D M-theory on a 7D G2 manifold automatically gives a supersymmetric 4D relativistic quantum field theory. The supersymmetry is softly broken by gluino condensation of the largest gauge group hidden sector, which runs fastest. The resulting gravitino mass is about 40 TeV, and the scalar masses and trilinears of the soft breaking Lagrangian have similar values. All solutions having electroweak symmetry breaking are in the two doublet decoupling region. The coefficient λ of the effective Higgs potential is calculable and determines Mh/MZ. Using the most recent match and run methods, and running down to the TeV scale gives Mh = 126 GeV, and decay BR within a few per cent of the SM Higgs. This was reported in summer 2011, before LHC data, though the result does not depend on any adjustable parameters so it would be unchanged whenever it was reported.

  17. Advances in neuroscience imply that harmful experiments in dogs are unethical.

    Science.gov (United States)

    Bailey, Jarrod; Pereira, Shiranee

    2018-01-01

    Functional MRI (fMRI) of fully awake and unrestrained dog 'volunteers' has been proven an effective tool to understand the neural circuitry and functioning of the canine brain. Although every dog owner would vouch that dogs are perceptive, cognitive, intuitive and capable of positive emotions/empathy, as indeed substantiated by ethological studies for some time, neurological investigations now corroborate this. These studies show that there exists a striking similarity between dogs and humans in the functioning of the caudate nucleus (associated with pleasure and emotion), and dogs experience positive emotions, empathic-like responses and demonstrate human bonding which, some scientists claim, may be at least comparable with human children. There exists an area analogous to the 'voice area' in the canine brain, enabling dogs to comprehend and respond to emotional cues/valence in human voices, and evidence of a region in the temporal cortex of dogs involved in the processing of faces, as also observed in humans and monkeys. We therefore contend that using dogs in invasive and/or harmful research, and toxicity testing, cannot be ethically justifiable. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  18. Minimizing Sum-MSE Implies Identical Downlink and Dual Uplink Power Allocations

    OpenAIRE

    Tenenbaum, Adam J.; Adve, Raviraj S.

    2009-01-01

    In the multiuser downlink, power allocation for linear precoders that minimize the sum of mean squared errors under a sum power constraint is a non-convex problem. Many existing algorithms solve an equivalent convex problem in the virtual uplink and apply a transformation based on uplink-downlink duality to find a downlink solution. In this letter, we analyze the optimality criteria for the power allocation subproblem in the virtual uplink, and demonstrate that the optimal solution leads to i...

  19. Field-warmed soil carbon changes imply high 21st-century modeling uncertainty

    Directory of Open Access Journals (Sweden)

    K. Todd-Brown

    2018-06-01

    Full Text Available The feedback between planetary warming and soil carbon loss has been the focus of considerable scientific attention in recent decades, due to its potential to accelerate anthropogenic climate change. The soil carbon temperature sensitivity is traditionally estimated from short-term respiration measurements – either from laboratory incubations that are artificially manipulated or from field measurements that cannot distinguish between plant and microbial respiration. To address these limitations of previous approaches, we developed a new method to estimate soil temperature sensitivity (Q10 of soil carbon directly from warming-induced changes in soil carbon stocks measured in 36 field experiments across the world. Variations in warming magnitude and control organic carbon percentage explained much of field-warmed organic carbon percentage (R2  =  0.96, revealing Q10 across sites of 2.2 [1.6, 2.7] 95 % confidence interval (CI. When these field-derived Q10 values were extrapolated over the 21st century using a post hoc correction of 20 Coupled Model Intercomparison Project Phase 5 (CMIP5 Earth system model outputs, the multi-model mean soil carbon stock changes shifted from the previous value of 88 ± 153 Pg carbon (weighted mean ± 1 SD to 19 ± 155 Pg carbon with a Q10-driven 95 % CI of 248 ± 191 to −95 ± 209 Pg carbon. On average, incorporating the field-derived Q10 values into Earth system model simulations led to reductions in the projected amount of carbon sequestered in the soil over the 21st century. However, the considerable parameter uncertainty led to extremely high variability in soil carbon stock projections within each model; intra-model uncertainty driven by the field-derived Q10 was as great as that between model variation. This study demonstrates that data integration should capture the variation of the system, as well as mean trends.

  20. Changing automatic behavior through self-monitoring: Does overt change also imply implicit change?

    NARCIS (Netherlands)

    Maas, J.; Hietbrink, L.; Rinck, M.; Keijsers, G.P.J.

    2013-01-01

    Background and objectives Self-monitoring of unwanted behavior is a common component of effective cognitive-behavioral therapy. Self-monitoring has often shown to lead to decreases in undesirable behavior. To investigate the underlying mechanisms of these ‘reactive effects’, we investigated whether

  1. 78 FR 13664 - Piedmont Triad Regional Water Authority; Notice of Termination of Exemption by Implied Surrender...

    Science.gov (United States)

    2013-02-28

    ... intake canal; (5)a penstock off the right side of the intake canal;(6) a powerhouse with two turbine/ generator units operating at a hydraulic head of 16-feet for a total installed capacity of 275 kW; (7)a 50...

  2. Genus-level taxonomic changes implied by the mitochondrial phylogeny of grey mullets (Teleostei: Mugilidae).

    Science.gov (United States)

    Durand, Jean-Dominique; Chen, Wei-Jen; Shen, Kang-Ning; Fu, Cuizhang; Borsa, Philippe

    2012-01-01

    A comprehensive mitochondrial phylogeny of the family Mugilidae (Durand et al., Mol. Phylogenet. Evol. 64 (2012) 73-92) demonstrated the polyphyly or paraphyly of a proportion of the 20 genera in the family. Based on these results, here we propose a revised classification with 25 genera, including 15 genera currently recognized as valid (Agonostomus, Aldrichetta, Cestraeus, Chaenomugil, Chelon, Crenimugil, Ellochelon, Joturus, Mugil, Myxus, Neomyxus, Oedalechilus, Rhinomugil, Sicamugil and Trachystoma), 7 resurrected genera [Dajaus (for Agonostomus monticola), Gracilimugil (for Liza argentea), Minimugil (for Sicamugil cascasia), Osteomugil (for several species currently under Moolgarda and Valamugil, including M. cunnesius, M. engeli, M. perusii, and V. robustus), Planiliza (for Indo-Pacific Chelon spp., Indo-Pacific Liza spp., and Paramugil parmatus), Plicomugil (for Oedalechilus labiosus), and Squalomugil (for Rhinomugil nasutus)] and 3 new genera: Neochelon gen. nov. (for Liza falcipinnis), Parachelon gen. nov. (for L. grandisquamis) and Pseudomyxus gen. nov. (for Myxus capensis). Genus Chelon was shown to include exclusively Chelon spp. and Liza spp. from the Atlantic and the Mediterranean, and Liza spp. species endemic to eastern southern Africa. Genus Crenimugil should now include C. crenilabis, Moolgarda seheli and V. buchanani. Genus names Liza, Moolgarda, Paramugil, Valamugil and Xenomugil should be abandoned because they are no longer valid. Further genetic evidence is required to confirm or infirm the validity of the genus Paracrenimugil Senou 1988. The mitochondrial phylogeny of the 25 genera from the present revision is the following: [(Sicamugil, (Minimugil, Rhinomugil)); Trachystoma; ((Myxus, Neomyxus), (Cestraeus, Chaenomugil, (Agonostomus, Dajaus, Joturus), Mugil)); (Aldrichetta, Gracilimugil); Neochelon gen. nov.; (Pseudomyxus gen. nov., (Chelon, Oedalechilus, Planiliza, Parachelon gen. nov.)); ((Squalomugil, (Ellochelon, Plicomugil)), (Crenimugil, Osteomugil))]. Agonostomus monticola and several species with large distribution ranges (including Moolgarda seheli, Mugil cephalus and M. curema) consist of separate lineages whose geographic distribution suggests they are cryptic species, thus warranting further taxonomic work in the Mugilidae at the infra-generic level. Copyright © 2012 Académie des sciences. Published by Elsevier SAS. All rights reserved.

  3. Does a deformation of special relativity imply energy dependent photon time delays?

    Science.gov (United States)

    Carmona, J. M.; Cortés, J. L.; Relancio, J. J.

    2018-01-01

    Theoretical arguments in favor of energy dependent photon time delays from a modification of special relativity (SR) have met with recent gamma ray observations that put severe constraints on the scale of such deviations. We review the case of the generality of this theoretical prediction in the case of a deformation of SR and find that, at least in the simple model based on the analysis of photon worldlines which is commonly considered, there are many scenarios compatible with a relativity principle which do not contain a photon time delay. This will be the situation for any modified dispersion relation which reduces to E=\\vert p\\vert for photons, independently of the quantum structure of spacetime. This fact opens up the possibility of a phenomenologically consistent relativistic generalization of SR with a new mass scale many orders of magnitude below the Planck mass.

  4. 21 CFR 101.65 - Implied nutrient content claims and related label statements.

    Science.gov (United States)

    2010-04-01

    ..., physiological, pathological, or other condition, where the claim identifies the special diet of which the food...., “as much fiber as an apple,” “Contains the same amount of Vitamin C as an 8 oz glass of orange juice... that is useful in creating a diet that is consistent with dietary recommendations if: (i) The food...

  5. Symmetrical kinematics does not imply symmetrical kinetics in people with transtibial amputation using cycling model.

    Science.gov (United States)

    Childers, W Lee; Kogler, Géza F

    2014-01-01

    People with amputation move asymmetrically with regard to kinematics (joint angles) and kinetics (joint forces and moments). Clinicians have traditionally sought to minimize kinematic asymmetries, assuming kinetic asymmetries would also be minimized. A cycling model evaluated locomotor asymmetries. Eight individuals with unilateral transtibial amputation pedaled with 172 mm-length crank arms on both sides (control condition) and with the crank arm length shortened to 162 mm on the amputated side (CRANK condition). Pedaling kinetics and limb kinematics were recorded. Joint kinetics, joint angles (mean and range of motion [ROM]), and pedaling asymmetries were calculated from force pedals and with a motion capture system. A one-way analysis of variance with tukey post hoc compared kinetics and kinematics across limbs. Statistical significance was set to p Pedaling asymmetries did not differ and were 23.0% +/= 9.8% and 23.2% +/= 12% for the control and CRANK conditions, respectively. Our results suggest that minimizing kinematic asymmetries does not relate to kinetic asymmetries as clinically assumed. We propose that future research should concentrate on defining acceptable asymmetry.

  6. Variability of Iberian upwelling implied by ERA-40 and ERA-Interim reanalyses

    Directory of Open Access Journals (Sweden)

    José M. R. Alves

    2013-05-01

    Full Text Available The Regional Ocean Modeling System ocean model is used to simulate the decadal evolution of the regional waters in offshore Iberia in response to atmospheric fields given by ECMWF ERA-40 (1961–2001 and ERA-Interim (1989–2008 reanalyses. The simulated sea surface temperature (SST fields are verified against satellite AVHRR SST, and they are analysed to characterise the variability and trends of coastal upwelling in the region. Opposing trends in upwelling frequency are found at the northern limit, where upwelling has been decreasing in recent decades, and at its southern edge, where there is some evidence of increased upwelling. These results confirm previous observational studies and, more importantly, indicate that observed SST trends are not only due to changes in radiative or atmospheric heat fluxes alone but also due to changes in upwelling dynamics, suggesting that such a process may be relevant in climate change scenarios.

  7. Seismic and Gas Analyses Imply Magmatic Intrusion at Iliamna Volcano, Alaska in 2012

    Science.gov (United States)

    Prejean, S. G.; Werner, C. A.; Buurman, H.; Doukas, M. P.; Kelly, P. J.; Kern, C.; Ketner, D.; Stihler, S.; Thurber, C. H.; West, M. E.

    2012-12-01

    In early 2012, Iliamna Volcano, an ice-covered andesitic stratovolcano located in the Cook Inlet region of Alaska, had a vigorous earthquake swarm that included both brittle-failure earthquakes (Mvolume has otherwise been seismically quiet except during a possible magmatic intrusion at Iliamna in 1996, when it sustained a similar swarm (Roman et al., 2004, J. Volc. Geotherm. Res., v. 130, p. 265-284). Analysis of the relative amplitudes between the small low-frequency and located brittle failure events indicates that their sources are geographically separate, with the low-frequency events sourced closer to the fumarolically active summit region, ~4 km north of the brittle failure events. Airborne gas-emission measurements on March 17 revealed emission rates of up to 2000 and 580 tonnes per day (t/d) of CO2 and SO2, respectively, and a molar C/S ratio of 5. Visual observations from the flight revealed unusually vigorous fumarole activity near the summit. Subsequent measurements on June 20 and 22 showed continued high emissions of up to 1190 and 440 t/d of CO2 and SO2, respectively, with a C/S ratio of 4. These emission measurements are similar to those measured during the height of the 1996 unrest episode and are significantly above background measurements between 1998 and August 2011, which were typically below 100 and 60 t/d of CO2 and SO2. Taken together, gas and seismic data suggest that the earthquake swarm was driven by magmatic intrusion. Gas flux rates are consistent with those measured for degassing andesitic magmas in the shallow crust at other Cook Inlet volcanoes. Increased heat and degassing likely caused small low-frequency events in the shallow hydrothermal system near the volcano's summit, and/or may have destabilized the glacier, triggering shallow low-frequency glacial events. This unrest episode demonstrates how magmatic intrusions can cause spatially disparate earthquake swarms in hydrothermal systems and on pre-existing crustal structures.

  8. Discovering Trigonometric Relationships Implied by the Law of Sines and the Law of Cosines

    Science.gov (United States)

    Skurnick, Ronald; Javadi, Mohammad

    2006-01-01

    The Law of Sines and The Law of Cosines are of paramount importance in the field of trigonometry because these two theorems establish relationships satisfied by the three sides and the three angles of any triangle. In this article, the authors use these two laws to discover a host of other trigonometric relationships that exist within any…

  9. Turning to account the implicit side effects of hydroelectric projects implying reservoirs

    International Nuclear Information System (INIS)

    Ionescu, S.

    1996-01-01

    Operation of the hydroelectric projects including relatively important water reservoirs provides implicitly side effects favorable to water management (increase of minimum provided flows, flood routing, etc) and to related fields (additional facilities for water supply, extension of the public utility networks as: road, telecommunication, electric lines, favoring the tourism and recreative activities). The paper suggests methodologies for economic and financial assessment of these effects, the turning to account of which, may increase the efficiency of the hydroelectric development and may stimulate the interest for new investments in the field.(author). 3 figs., 5 refs

  10. Multiplying the use of space and what it implies in practice: a cross-case analysis

    DEFF Research Database (Denmark)

    Brinkoe, Rikke; Nielsen, Susanne Balslev

    2018-01-01

    are generally overlooked, despite its importance for the user experience and the degree of success with shared space initiatives. The purpose of this study is to increase the knowledge of shared space and the complex processes involved in realising multiple use of space. Design/methodology/approach To achieve......, supported by specific recommendations regarding attention to issues of territoriality, involvement and practicalities. Originality/value Not much scientific work has been conducted on the topic of shared space in a facilities management context, and this study adds to the so far limited knowledge within...

  11. Individual Differences in Students' Complex Problem Solving Skills: How They Evolve and What They Imply

    Science.gov (United States)

    Wüstenberg, Sascha; Greiff, Samuel; Vainikainen, Mari-Pauliina; Murphy, Kevin

    2016-01-01

    Changes in the demands posed by increasingly complex workplaces in the 21st century have raised the importance of nonroutine skills such as complex problem solving (CPS). However, little is known about the antecedents and outcomes of CPS, especially with regard to malleable external factors such as classroom climate. To investigate the relations…

  12. Does campaign finance imply political favors? The case of the 1998 Brazilian elections

    NARCIS (Netherlands)

    Feijen, E.

    2005-01-01

    This paper provides empirical evidence that campaign contributions are strongly associated with expectations of future firm-specific political favors. Using a novel dataset, we find that during the 1998 elections in Brazil higher campaign contributions to federal deputies were robustly associated

  13. Polynomial algorithms that prove an NP-hard hypothesis implies an NP-hard conclusion

    NARCIS (Netherlands)

    Bauer, D.; Broersma, Haitze J.; Morgana, A.; Schmeichel, E.

    2002-01-01

    An example of such a theorem is the well-known Chvátal–Erdős Theorem, which states that every graph G with ακ is hamiltonian. Here κ is the vertex connectivity of G and α is the cardinality of a largest set of independent vertices of G. In another paper Chvátal points out that the proof of this

  14. Advances in neuroscience imply that harmful experiments in dogs are unethical

    Science.gov (United States)

    Pereira, Shiranee

    2018-01-01

    Functional MRI (fMRI) of fully awake and unrestrained dog ’volunteers' has been proven an effective tool to understand the neural circuitry and functioning of the canine brain. Although every dog owner would vouch that dogs are perceptive, cognitive, intuitive and capable of positive emotions/empathy, as indeed substantiated by ethological studies for some time, neurological investigations now corroborate this. These studies show that there exists a striking similarity between dogs and humans in the functioning of the caudate nucleus (associated with pleasure and emotion), and dogs experience positive emotions, empathic-like responses and demonstrate human bonding which, some scientists claim, may be at least comparable with human children. There exists an area analogous to the ’voice area' in the canine brain, enabling dogs to comprehend and respond to emotional cues/valence in human voices, and evidence of a region in the temporal cortex of dogs involved in the processing of faces, as also observed in humans and monkeys. We therefore contend that using dogs in invasive and/or harmful research, and toxicity testing, cannot be ethically justifiable. PMID:28739639

  15. Optimal Claiming Strategies in Bonus Malus Systems and Implied Markov Chains

    Directory of Open Access Journals (Sweden)

    Arthur Charpentier

    2017-11-01

    Full Text Available In this paper, we investigate the impact of the accident reporting strategy of drivers, within a Bonus-Malus system. We exhibit the induced modification of the corresponding class level transition matrix and derive the optimal reporting strategy for rational drivers. The hunger for bonuses induces optimal thresholds under which, drivers do not claim their losses. Mathematical properties of the induced level class process are studied. A convergent numerical algorithm is provided for computing such thresholds and realistic numerical applications are discussed.

  16. Restoration of fMRI Decodability Does Not Imply Latent Working Memory States

    Science.gov (United States)

    Schneegans, Sebastian; Bays, Paul M.

    2018-01-01

    Recent imaging studies have challenged the prevailing view that working memory is mediated by sustained neural activity. Using machine learning methods to reconstruct memory content, these studies found that previously diminished representations can be restored by retrospective cueing or other forms of stimulation. These findings have been interpreted as evidence for an activity-silent working memory state that can be reactivated dependent on task demands. Here, we test the validity of this conclusion by formulating a neural process model of working memory based on sustained activity and using this model to emulate a spatial recall task with retrocueing. The simulation reproduces both behavioral and fMRI results previously taken as evidence for latent states, in particular the restoration of spatial reconstruction quality following an informative cue. Our results demonstrate that recovery of the decodability of an imaging signal does not provide compelling evidence for an activity-silent working memory state. PMID:28820674

  17. Deciduous forest responses to temperature, precipitation, and drought imply complex climate change impacts.

    Science.gov (United States)

    Xie, Yingying; Wang, Xiaojing; Silander, John A

    2015-11-03

    Changes in spring and autumn phenology of temperate plants in recent decades have become iconic bio-indicators of rapid climate change. These changes have substantial ecological and economic impacts. However, autumn phenology remains surprisingly little studied. Although the effects of unfavorable environmental conditions (e.g., frost, heat, wetness, and drought) on autumn phenology have been observed for over 60 y, how these factors interact to influence autumn phenological events remain poorly understood. Using remotely sensed phenology data from 2001 to 2012, this study identified and quantified significant effects of a suite of environmental factors on the timing of fall dormancy of deciduous forest communities in New England, United States. Cold, frost, and wet conditions, and high heat-stress tended to induce earlier dormancy of deciduous forests, whereas moderate heat- and drought-stress delayed dormancy. Deciduous forests in two eco-regions showed contrasting, nonlinear responses to variation in these explanatory factors. Based on future climate projection over two periods (2041-2050 and 2090-2099), later dormancy dates were predicted in northern areas. However, in coastal areas earlier dormancy dates were predicted. Our models suggest that besides warming in climate change, changes in frost and moisture conditions as well as extreme weather events (e.g., drought- and heat-stress, and flooding), should also be considered in future predictions of autumn phenology in temperate deciduous forests. This study improves our understanding of how multiple environmental variables interact to affect autumn phenology in temperate deciduous forest ecosystems, and points the way to building more mechanistic and predictive models.

  18. Stable power laws in variable economies; Lotka-Volterra implies Pareto-Zipf

    Science.gov (United States)

    Solomon, S.; Richmond, P.

    2002-05-01

    In recent years we have found that logistic systems of the Generalized Lotka-Volterra type (GLV) describing statistical systems of auto-catalytic elements posses power law distributions of the Pareto-Zipf type. In particular, when applied to economic systems, GLV leads to power laws in the relative individual wealth distribution and in market returns. These power laws and their exponent α are invariant to arbitrary variations in the total wealth of the system and to other endogenously and exogenously induced variations.

  19. Discretization independence implies non-locality in 4D discrete quantum gravity

    Science.gov (United States)

    Dittrich, Bianca; Kamiński, Wojciech; Steinhaus, Sebastian

    2014-12-01

    The 4D Regge action is invariant under 5-1 and 4-2 Pachner moves, which define a subset of (local) changes of the triangulation. Given this fact, one might hope to find a local path integral measure that makes the quantum theory invariant under these moves and hence makes the theory partially triangulation invariant. We show that such a local invariant path integral measure does not exist for the 4D linearized Regge theory. To this end we uncover an interesting geometric interpretation for the Hessian of the 4D Regge action. This geometric interpretation will allow us to prove that the determinant of the Hessian of the 4D Regge action does not factorize over four-simplices or subsimplices. It furthermore allows us to determine configurations where this Hessian vanishes, which only appears to be the case in degenerate backgrounds or if one allows for different orientations of the simplices. We suggest a non-local measure factor that absorbs the non-local part of the determinant of the Hessian under 5-1 moves as well as a local measure factor that is preserved for very special configurations.

  20. Market price of risk implied by Asian-style electricity options and futures

    Energy Technology Data Exchange (ETDEWEB)

    Weron, Rafal [Hugo Steinhaus Center for Stochastic Methods, Institute of Mathematics and Computer Science, Wroclaw University of Technology, 50-370 Wroclaw (Poland)

    2008-05-15

    In this paper we propose a jump-diffusion type model which recovers the main characteristics of electricity spot price dynamics in the Nordic market, including seasonality, mean-reversion and spiky behavior. We show how the calibration of the market price of risk to actively traded futures contracts allows for efficient valuation of Nord Pool's Asian-style options written on the spot electricity price. Furthermore, we study the evolution of the market price of risk (and the risk premium) over a three year time period and compare the obtained results with those reported in the literature. (author)

  1. Discretization independence implies non-locality in 4D discrete quantum gravity

    International Nuclear Information System (INIS)

    Dittrich, Bianca; Kamiński, Wojciech; Steinhaus, Sebastian

    2014-01-01

    The 4D Regge action is invariant under 5–1 and 4–2 Pachner moves, which define a subset of (local) changes of the triangulation. Given this fact, one might hope to find a local path integral measure that makes the quantum theory invariant under these moves and hence makes the theory partially triangulation invariant. We show that such a local invariant path integral measure does not exist for the 4D linearized Regge theory. To this end we uncover an interesting geometric interpretation for the Hessian of the 4D Regge action. This geometric interpretation will allow us to prove that the determinant of the Hessian of the 4D Regge action does not factorize over four-simplices or subsimplices. It furthermore allows us to determine configurations where this Hessian vanishes, which only appears to be the case in degenerate backgrounds or if one allows for different orientations of the simplices. We suggest a non-local measure factor that absorbs the non-local part of the determinant of the Hessian under 5–1 moves as well as a local measure factor that is preserved for very special configurations. (paper)

  2. Limited capacity of working memory in unihemispheric random walks implies conceivable slow dispersal.

    Science.gov (United States)

    Wei, Kun; Zhong, Suchuan

    2017-08-01

    Phenomenologically inspired by dolphins' unihemispheric sleep, we introduce a minimal model for random walks with physiological memory. The physiological memory consists of long-term memory which includes unconscious implicit memory and conscious explicit memory, and working memory which serves as a multi-component system for integrating, manipulating and managing short-term storage. The model assumes that the sleeping state allows retrievals of episodic objects merely from the episodic buffer where these memory objects are invoked corresponding to the ambient objects and are thus object-oriented, together with intermittent but increasing use of implicit memory in which decisions are unconsciously picked up from historical time series. The process of memory decay and forgetting is constructed in the episodic buffer. The walker's risk attitude, as a product of physiological heuristics according to the performance of objected-oriented decisions, is imposed on implicit memory. The analytical results of unihemispheric random walks with the mixture of object-oriented and time-oriented memory, as well as the long-time behavior which tends to the use of implicit memory, are provided, indicating the common sense that a conservative risk attitude is inclinable to slow movement.

  3. Does morphological convergence imply functional similarity? A test using the evolution of quadrupedalism in ornithischian dinosaurs.

    Science.gov (United States)

    Maidment, Susannah C R; Barrett, Paul M

    2012-09-22

    Convergent morphologies are thought to indicate functional similarity, arising because of a limited number of evolutionary or developmental pathways. Extant taxa displaying convergent morphologies are used as analogues to assess function in extinct taxa with similar characteristics. However, functional studies of extant taxa have shown that functional similarity can arise from differing morphologies, calling into question the paradigm that form and function are closely related. We test the hypothesis that convergent skeletal morphology indicates functional similarity in the fossil record using ornithischian dinosaurs. The rare transition from bipedality to quadrupedality occurred at least three times independently in this clade, resulting in a suite of convergent osteological characteristics. We use homology rather than analogy to provide an independent line of evidence about function, reconstructing soft tissues using the extant phylogenetic bracket and applying biomechanical concepts to produce qualitative assessments of muscle leverage. We also optimize character changes to investigate the sequence of character acquisition. Different lineages of quadrupedal ornithischian dinosaur stood and walked differently from each other, falsifying the hypothesis that osteological convergence indicates functional similarity. The acquisition of features correlated with quadrupedalism generally occurs in the same order in each clade, suggesting underlying developmental mechanisms that act as evolutionary constraints.

  4. Quantitative radiomics: impact of stochastic effects on textural feature analysis implies the need for standards.

    Science.gov (United States)

    Nyflot, Matthew J; Yang, Fei; Byrd, Darrin; Bowen, Stephen R; Sandison, George A; Kinahan, Paul E

    2015-10-01

    Image heterogeneity metrics such as textural features are an active area of research for evaluating clinical outcomes with positron emission tomography (PET) imaging and other modalities. However, the effects of stochastic image acquisition noise on these metrics are poorly understood. We performed a simulation study by generating 50 statistically independent PET images of the NEMA IQ phantom with realistic noise and resolution properties. Heterogeneity metrics based on gray-level intensity histograms, co-occurrence matrices, neighborhood difference matrices, and zone size matrices were evaluated within regions of interest surrounding the lesions. The impact of stochastic variability was evaluated with percent difference from the mean of the 50 realizations, coefficient of variation and estimated sample size for clinical trials. Additionally, sensitivity studies were performed to simulate the effects of patient size and image reconstruction method on the quantitative performance of these metrics. Complex trends in variability were revealed as a function of textural feature, lesion size, patient size, and reconstruction parameters. In conclusion, the sensitivity of PET textural features to normal stochastic image variation and imaging parameters can be large and is feature-dependent. Standards are needed to ensure that prospective studies that incorporate textural features are properly designed to measure true effects that may impact clinical outcomes.

  5. Market price of risk implied by Asian-style electricity options and futures

    International Nuclear Information System (INIS)

    Weron, Rafal

    2008-01-01

    In this paper we propose a jump-diffusion type model which recovers the main characteristics of electricity spot price dynamics in the Nordic market, including seasonality, mean-reversion and spiky behavior. We show how the calibration of the market price of risk to actively traded futures contracts allows for efficient valuation of Nord Pool's Asian-style options written on the spot electricity price. Furthermore, we study the evolution of the market price of risk (and the risk premium) over a three year time period and compare the obtained results with those reported in the literature. (author)

  6. 78 FR 50411 - Christopher M. Anthony; Notice of Termination of Exemption by Implied Surrender and Soliciting...

    Science.gov (United States)

    2013-08-19

    ... Internet (eFiling) in lieu of paper. Please refer to the instructions on the Commission's Web site under... powerhouse, is a 14-foot-high, 250-foot- long stone masonry structure owned by the Town of Frankfort. k...

  7. Psychological variables implied in the therapeutic effect of ayahuasca: A contextual approach.

    Science.gov (United States)

    Franquesa, Alba; Sainz-Cort, Alberto; Gandy, Sam; Soler, Joaquim; Alcázar-Córcoles, Miguel Ángel; Bouso, José Carlos

    2018-04-04

    Ayahuasca is a psychedelic decoction originating from Amazonia. The ayahuasca-induced introspective experience has been shown to have potential benefits in the treatment of several pathologies, to protect mental health and to improve neuropsychological functions and creativity, and boost mindfulness. The underlying psychological processes related to the use of ayahuasca in a psychotherapeutic context are not yet well described in the scientific literature, but there is some evidence to suggest that psychological variables described in psychotherapies could be useful in explaining the therapeutic effects of the brew. In this study we explore the link between ayahuasca use and Decentering, Values and Self, comparing subjects without experience of ayahuasca (n = 41) with subjects with experience (n = 81). Results confirm that ayahuasca users scored higher than non-users in Decentering and Positive self, but not in Valued living, Life fulfillment, Self in social relations, Self in close relations and General self. Scores in Decentering were higher in the more experienced subjects (more than 15 occasions) than in those with less experience (less than 15 occasions). Our results show that psychological process variables may explain the outcomes in ayahuasca psychotherapy. The introduction of these variables is warranted in future ayahuasca therapeutic studies. Copyright © 2018 Elsevier B.V. All rights reserved.

  8. Late to middle Pleistocene Arctic glacial history implied from a sedimentary record from the Northwind Ridge

    Science.gov (United States)

    Liu, Y.; Dong, L.; Shi, X.; Zhu, A.

    2017-12-01

    Abstract: Sediment core ARC6-C21 collected from the Northwind Ridge, western Arctic Ocean, covers the late to middle Quaternary (Marine Isotope Stages (MIS) 1-11), as estimated by correlation to earlier proposed Arctic Ocean stratigraphies and AMS14C dating of the youngest sediments. Detailed examination of the elemental composition of sediment along with grain size in core ARC6-C21 provides important new information about sedimentary environments and provenance. We use increased contents of coarse debris as an indicator of glacier collapse events at the margins of the western Arctic Ocean, and identify the provenance of these events from geochemical composition. Notably, peaks of MgO and CaO, including large dropstones, presumably track the Laurentide Ice Sheet (LIS) discharge events to the Arctic Ocean. Major LIS inputs occurred during the stratigraphic intervals estimated as MIS 3, intra-MIS 5 and 7 events, MIS 8, and MIS 10. Inputs from the East Siberian Ice Sheet (ESIS) and/or Eurasia Ice Sheet (EIS)are inferred from peaks of SiO2, K2O and Na2O associated with coarse sediment. Major ESIS and/or EIS sedimentary events occurred in the intervals estimated as MIS 2, MIS 4, MIS 6, MIS 8 and MIS 10. Keywords: Sediment core, Pleistocene, western Arctic Ocean, geochemistry, grain size, sediment provenance, glaciations

  9. NEUTRINO mass textures and the nature of new physics implied by present neutrino data

    International Nuclear Information System (INIS)

    Mohapatra, R.N.

    1997-01-01

    If all the indications for neutrino oscillations observed in the solar, atmospheric neutrino data as well as in the LSND experiment are borned out by the ongoing and future experiments, then they severely constrain the neutrino mass texture. In particular, the need for an extra ultra-light sterile neutrino species is hard to avoid. Such an extra neutrino has profound implication not only for physics beyond the standard model but even perhaps for physics beyond conventional grand unification. A scenario involving a parallel (or shadow) universe that interacts with the familiar universe only via the gravitational interactions where the ultra-lightness of the sterile neutrino follows from the same physics that explains the near masslessness of the familiar neutrinos is discussed in the presentation

  10. Sediment of a Central European Mountain Lake Implies an Extraterrestrial Impact at the Younger Dryas Onset

    Czech Academy of Sciences Publication Activity Database

    Vondrák, D.; Kletetschka, G.; Hrubá, J.; Nábělek, L.; Procházka, V.; Svitavská-Svobodová, Helena; Bobek, Přemysl; Hořická, Zuzana; Kadlec, Jaroslav; Takáč, M.; Stuchlík, Evžen

    2017-01-01

    Roč. 52, S1 (2017), A373-A373, č. článku 6230. ISSN 1086-9379. [Annual Meeting of the Meteoritical Society /80./. 23.07.2017-28.07.2017, Santa Fe] R&D Projects: GA ČR(CZ) GA17-05935S Institutional support: RVO:67985939 ; RVO:60077344 ; RVO:67985530 Keywords : Younger Dryas * Extraterrestrial Impact * Central Europe Subject RIV: DG - Athmosphere Sciences, Meteorology; DA - Hydrology ; Limnology (BC-A); DE - Earth Magnetism, Geodesy, Geography (GFU-E) OBOR OECD: Plant sciences, botany

  11. 75 FR 41858 - Notice of Termination of License by Implied Surrender and Soliciting Comments, Protests, and...

    Science.gov (United States)

    2010-07-19

    ...,000-kVA transformer, and a 70-foot-long, 15-kV transmission line; (6) a tailrace; and (7) other... Hydro Electric Company (Roosevelt Hydro). 16 FERC ] 62,040 (1981). The project has not operated since...

  12. Identification of eight novel coagulation factor XIII subunit A mutations: implied consequences for structure and function.

    Science.gov (United States)

    Ivaskevicius, Vytautas; Biswas, Arijit; Bevans, Carville; Schroeder, Verena; Kohler, Hans Peter; Rott, Hannelore; Halimeh, Susan; Petrides, Petro E; Lenk, Harald; Krause, Manuele; Miterski, Bruno; Harbrecht, Ursula; Oldenburg, Johannes

    2010-06-01

    Severe hereditary coagulation factor XIII deficiency is a rare homozygous bleeding disorder affecting one person in every two million individuals. In contrast, heterozygous factor XIII deficiency is more common, but usually not associated with severe hemorrhage such as intracranial bleeding or hemarthrosis. In most cases, the disease is caused by F13A gene mutations. Causative mutations associated with the F13B gene are rarer. We analyzed ten index patients and three relatives for factor XIII activity using a photometric assay and sequenced their F13A and F13B genes. Additionally, structural analysis of the wild-type protein structure from a previously reported X-ray crystallographic model identified potential structural and functional effects of the missense mutations. All individuals except one were heterozygous for factor XIIIA mutations (average factor XIII activity 51%), while the remaining homozygous individual was found to have severe factor XIII deficiency (<5% of normal factor XIII activity). Eight of the 12 heterozygous patients exhibited a bleeding tendency upon provocation. The identified missense (Pro289Arg, Arg611His, Asp668Gly) and nonsense (Gly390X, Trp664X) mutations are causative for factor XIII deficiency. A Gly592Ser variant identified in three unrelated index patients, as well as in 200 healthy controls (minor allele frequency 0.005), and two further Tyr167Cys and Arg540Gln variants, represent possible candidates for rare F13A gene polymorphisms since they apparently do not have a significant influence on the structure of the factor XIIIA protein. Future in vitro expression studies of the factor XIII mutations are required to confirm their pathological mechanisms.

  13. Implied Spatial Meaning and Visuospatial Bias: Conceptual Processing Influences Processing of Visual Targets and Distractors.

    Directory of Open Access Journals (Sweden)

    Davood G Gozli

    Full Text Available Concepts with implicit spatial meaning (e.g., "hat", "boots" can bias visual attention in space. This result is typically found in experiments with a single visual target per trial, which can appear at one of two locations (e.g., above vs. below. Furthermore, the interaction is typically found in the form of speeded responses to targets appearing at the compatible location (e.g., faster responses to a target above fixation, after reading "hat". It has been argued that these concept-space interactions could also result from experimentally-induced associations between the binary set of locations and the conceptual categories with upward and downward meaning. Thus, rather than reflecting a conceptually driven spatial bias, the effect could reflect a benefit for compatible cue-target sequences that occurs only after target onset. We addressed these concerns by going beyond a binary set of locations and employing a search display consisting of four items (above, below, left, and right. Within each search trial, before performing a visual search task, participants performed a conceptual task involving concepts with implicit upward or downward meaning. The search display, in addition to including a target, could also include a salient distractor. Assuming a conceptually driven visual bias, we expected to observe, first, a benefit for target processing at the compatible location and, second, an increase in the cost of the salient distractor. The findings confirmed both predictions, suggesting that concepts do indeed generate a spatial bias. Finally, results from a control experiment, without the conceptual task, suggest the presence of an axis-specific effect, in addition to the location-specific effect, suggesting that concepts might cause both location-specific and axis-specific spatial bias. Taken together, our findings provide additional support for the involvement of spatial processing in conceptual understanding.

  14. Differences in nutrient requirements imply a non-linear emergence of leaders in animal groups.

    Directory of Open Access Journals (Sweden)

    Cédric Sueur

    Full Text Available Collective decision making and especially leadership in groups are among the most studied topics in natural, social, and political sciences. Previous studies have shown that some individuals are more likely to be leaders because of their social power or the pertinent information they possess. One challenge for all group members, however, is to satisfy their needs. In many situations, we do not yet know how individuals within groups distribute leadership decisions between themselves in order to satisfy time-varying individual requirements. To gain insight into this problem, we build a dynamic model where group members have to satisfy different needs but are not aware of each other's needs. Data about needs of animals come from real data observed in macaques. Several studies showed that a collective movement may be initiated by a single individual. This individual may be the dominant one, the oldest one, but also the one having the highest physiological needs. In our model, the individual with the lowest reserve initiates movements and decides for all its conspecifics. This simple rule leads to a viable decision-making system where all individuals may lead the group at one moment and thus suit their requirements. However, a single individual becomes the leader in 38% to 95% of cases and the leadership is unequally (according to an exponential law distributed according to the heterogeneity of needs in the group. The results showed that this non-linearity emerges when one group member reaches physiological requirements, mainly the nutrient ones - protein, energy and water depending on weight - superior to those of its conspecifics. This amplification may explain why some leaders could appear in animal groups without any despotism, complex signalling, or developed cognitive ability.

  15. Locality at the boundary implies gap in the bulk for 2D PEPS

    DEFF Research Database (Denmark)

    Kastoryano, Michael J.; Lucia, Angelo; Perez-Garcia, David

    2018-01-01

    Proving that the parent Hamiltonian of a Projected Entangled Pair State (PEPS) is gapped remains an important open problem. We take a step forward in solving this problem by showing that if the boundary state of any rectangular subregion is a quasi-local Gibbs state of the virtual indices, then t...... boundary theories and dynamical properties in an interacting many body system. We show that the proof can be extended to MPO-injective PEPS, and speculate that the assumption on the locality of the boundary Hamiltonian follows from exponential decay of correlations in the bulk....

  16. Motor mapping of implied actions during perception of emotional body language

    NARCIS (Netherlands)

    Borgomaneri, Sara; Gazzola, Valeria; Avenanti, Alessio

    Background: Perceiving and understanding emotional cues is critical for survival. Using the International Affective Picture System (IAPS) previous TMS studies have found that watching humans in emotional pictures increases motor excitability relative to seeing landscapes or household objects,

  17. Rising atmospheric CO2 concentration may imply higher risk of Fusarium mycotoxin contamination of wheat grains.

    Science.gov (United States)

    Bencze, Szilvia; Puskás, Katalin; Vida, Gyula; Karsai, Ildikó; Balla, Krisztina; Komáromi, Judit; Veisz, Ottó

    2017-08-01

    Increasing atmospheric CO 2 concentration not only has a direct impact on plants but also affects plant-pathogen interactions. Due to economic and health-related problems, special concern was given thus in the present work to the effect of elevated CO 2 (750 μmol mol -1 ) level on the Fusarium culmorum infection and mycotoxin contamination of wheat. Despite the fact that disease severity was found to be not or little affected by elevated CO 2 in most varieties, as the spread of Fusarium increased only in one variety, spike grain number and/or grain weight decreased significantly at elevated CO 2 in all the varieties, indicating that Fusarium infection generally had a more dramatic impact on the grain yield at elevated CO 2 than at the ambient level. Likewise, grain deoxynivalenol (DON) content was usually considerably higher at elevated CO 2 than at the ambient level in the single-floret inoculation treatment, suggesting that the toxin content is not in direct relation to the level of Fusarium infection. In the whole-spike inoculation, DON production did not change, decreased or increased depending on the variety × experiment interaction. Cooler (18 °C) conditions delayed rachis penetration while 20 °C maximum temperature caused striking increases in the mycotoxin contents, resulting in extremely high DON values and also in a dramatic triggering of the grain zearalenone contamination at elevated CO 2 . The results indicate that future environmental conditions, such as rising CO 2 levels, may increase the threat of grain mycotoxin contamination.

  18. A simulation study of gene-by-environment interactions in GWAS implies ample hidden effects

    Science.gov (United States)

    Marigorta, Urko M.; Gibson, Greg

    2014-01-01

    The switch to a modern lifestyle in recent decades has coincided with a rapid increase in prevalence of obesity and other diseases. These shifts in prevalence could be explained by the release of genetic susceptibility for disease in the form of gene-by-environment (GxE) interactions. Yet, the detection of interaction effects requires large sample sizes, little replication has been reported, and a few studies have demonstrated environmental effects only after summing the risk of GWAS alleles into genetic risk scores (GRSxE). We performed extensive simulations of a quantitative trait controlled by 2500 causal variants to inspect the feasibility to detect gene-by-environment interactions in the context of GWAS. The simulated individuals were assigned either to an ancestral or a modern setting that alters the phenotype by increasing the effect size by 1.05–2-fold at a varying fraction of perturbed SNPs (from 1 to 20%). We report two main results. First, for a wide range of realistic scenarios, highly significant GRSxE is detected despite the absence of individual genotype GxE evidence at the contributing loci. Second, an increase in phenotypic variance after environmental perturbation reduces the power to discover susceptibility variants by GWAS in mixed cohorts with individuals from both ancestral and modern environments. We conclude that a pervasive presence of gene-by-environment effects can remain hidden even though it contributes to the genetic architecture of complex traits. PMID:25101110

  19. Incompatible messages implied from positive and negative frames regarding trust and choice decisions

    NARCIS (Netherlands)

    Keren, G.

    2007-01-01

    Following common wisdom, if one trusts agent A more than B, then one should prefer to conduct transactions with the former rather than with the latter agent. Several experiments are presented that are incompatible with this conjecture. For example, when faced with a choice between two butchers,

  20. Goal Setting Theory: What It Implies for Strategic Human Resource Development

    OpenAIRE

    AVCI, Ömer

    2016-01-01

    Among numerous motivational theories, goal setting theory particularly can serve strategic human resource development practices. The goal-setting theory suggests that organizational goals have to be communicated clearly and the goals need to be specific enough. Another feature of goal-setting is that they need not be too easy or perceived to be impossible to fulfill. SHRD personnel should keep in mind that some employees prefer to work individually toward fulfilling a goal, while others prefe...

  1. Earthquake potential in California-Nevada implied by correlation of strain rate and seismicity

    Science.gov (United States)

    Zeng, Yuehua; Petersen, Mark D.; Shen, Zheng-Kang

    2018-01-01

    Rock mechanics studies and dynamic earthquake simulations show that patterns of seismicity evolve with time through (1) accumulation phase, (2) localization phase, and (3) rupture phase. We observe a similar pattern of changes in seismicity during the past century across California and Nevada. To quantify these changes, we correlate GPS strain rates with seismicity. Earthquakes of M > 6.5 are collocated with regions of highest strain rates. By contrast, smaller magnitude earthquakes of M ≥ 4 show clear spatiotemporal changes. From 1933 to the late 1980s, earthquakes of M ≥ 4 were more diffused and broadly distributed in both high and low strain rate regions (accumulation phase). From the late 1980s to 2016, earthquakes were more concentrated within the high strain rate areas focused on the major fault strands (localization phase). In the same time period, the rate of M > 6.5 events also increased significantly in the high strain rate areas. The strong correlation between current strain rate and the later period of seismicity indicates that seismicity is closely related to the strain rate. The spatial patterns suggest that before the late 1980s, the strain rate field was also broadly distributed because of the stress shadows from previous large earthquakes. As the deformation field evolved out of the shadow in the late 1980s, strain has refocused on the major fault systems and we are entering a period of increased risk for large earthquakes in California.

  2. Body Mass Index below Obesity Threshold Implies Similar Cardiovascular Risk among Various Polycystic Ovary Syndrome Phenotypes.

    Science.gov (United States)

    Bagir, Gulay Simsek; Bakiner, Okan S; Bozkirli, Emre; Cavlak, Gulhan; Serinsoz, Hulya; Ertorer, M Eda

    2016-01-01

    The aim of this study was to determine the cardiometabolic risk factors in different polycystic ovary syndrome (PCOS) phenotypes. This cross-sectional study was performed between 2010 and 2011. Eighty-nine patients with PCOS and 25 age- and weight-matched healthy controls were included in the study. Patients were grouped using the Rotterdam 2003 criteria as: group 1, oligomenorrhea and/or anovulation (ANOV) and hyperandrogenemia (HA) and/or hyperandrogenism (n = 23); group 2, ANOV and polycystic ovaries (PCO; n = 22); group 3, HA and PCO (n = 22); group 4, ANOV, HA and PCO (n = 22); group 5, controls (n = 25). Laboratory blood tests for diagnosis and cardiometabolic risk assessments were performed. Insulin resistance (IR) was calculated in all patients with the homeostasis model assessment of IR (HOMA-IR) formula. An euglycemic hyperinsulinemic clamp test was performed on 5 randomly selected cases in each subgroup, making 25 cases in total, and indicated as the 'M' value (mg/kg/min), which is the total body glucose disposal rate. The mean BMl values of the groups were: group 1, 26.1 ± 5.3; group 2, 27.9 ± 5.2; group 3, 24.3 ± 4.2; group 4, 27.9 ± 7.5; group 5, 24.7 ± 5.2 (p > 0.05). There were no differences in the lipid profile, plasma glucose, HOMA-IR, insulin and M values between the groups (p > 0.05). Phenotypes with oligomenorrhea/anovulation (groups 1, 2 and 4) were more obese than group 3 (p = 0.039). The cardiometabolic risk profile was similar among the PCOS subgroups. This finding could be attributed to the mean BMl values, which, being below 30, were not within the obesity range. Obesity appeared to be an important determinant of high cardiovascular risk in PCOS. © 2015 S. Karger AG, Basel.

  3. Potential physiological effects of pharmaceutical compounds in Atlantic salmon (Salmo salar) implied by transcriptomic analysis.

    Science.gov (United States)

    Hampel, Miriam; Alonso, Esteban; Aparicio, Irene; Bron, James E; Santos, Juan Luis; Taggart, John B; Leaver, Michael J

    2010-05-01

    Pharmaceuticals are emerging pollutants widely used in everyday urban activities which can be detected in surface, ground, and drinking waters. Their presence is derived from consumption of medicines, disposal of expired medications, release of treated and untreated urban effluents, and from the pharmaceutical industry. Their growing use has become an alarming environmental problem which potentially will become dangerous in the future. However, there is still a lack of knowledge about long-term effects in non-target organisms as well as for human health. Toxicity testing has indicated a relatively low acute toxicity to fish species, but no information is available on possible sublethal effects. This study provides data on the physiological pathways involved in the exposure of Atlantic salmon as representative test species to three pharmaceutical compounds found in ground, surface, and drinking waters based on the evaluation of the xenobiotic-induced impairment resulting in the activation and silencing of specific genes. Individuals of Atlantic salmon (Salmo salar) parr were exposed during 5 days to environmentally relevant concentrations of three representative pharmaceutical compounds with high consumption rates: the analgesic acetaminophen (54.77+/-34.67 microg L(-1)), the anticonvulsant carbamazepine (7.85+/-0.13 microg L(-1)), and the beta-blocker atenolol (11.08+/-7.98 microg L(-1)). Five immature males were selected for transcriptome analysis in brain tissues by means of a 17k salmon cDNA microarray. For this purpose, mRNA was isolated and reverse-transcribed into cDNA which was labeled with fluorescent dyes and hybridized against a common pool to the arrays. Lists of significantly up- and down-regulated candidate genes were submitted to KEGG (Kyoto Encyclopedia of Genes and Genomes) in order to analyze for induced pathways and to evaluate the usefulness of this method in cases of not completely annotated test organisms. Exposure during 5 days to environmentally relevant concentrations of the selected pharmaceutical compounds acetaminophen, carbamazepine, and atenolol produced differences in the expression of 659, 700, and 480 candidate genes, respectively. KEGG annotation numbers (KO annotations) were obtained for between 26.57% and 33.33% of these differently expressed genes per treatment in comparison to non-exposure conditions. Pathways that showed to be induced did not always follow previously reported targets or metabolic routes for the employed treatments; however, several other pathways have been found (four or more features) to be significantly induced. Energy-related pathways have been altered under exposure in all the selected treatments, indicating a possible energy budget leakage due to additional processes resulting from the exposure to environmental contaminants. Observed induction of pathways may indicate additional processes involved in the mode of action of the selected pharmaceuticals which may not have been detected with conventional methods like quantitative PCR in which only suspected features are analyzed punctually for effects. The employment of novel high-throughput screening techniques in combination with global pathway analysis methods, even if the organism is not completely annotated, allows the examination of a much broader range of candidates for potential effects of exposure at the gene level. The continuously growing number of annotations of representative species relevant for environmental quality testing is facilitating pathway analysis processes for not completely annotated organisms. KEGG has shown to be a useful tool for the analysis of induced pathways from data generated by microarray techniques with the selected pharmaceutical contaminants acetaminophen, carbamazepine, and atenolol, but further studies have to be carried out in order to determine if a similar expression pattern in terms of fold change quantity and pathways is observed after long-term exposure. Together with the information obtained in this study, it will then be possible to evaluate the potential risk that the continuous release of these compounds may have on the environment and ecosystem functioning.

  4. Natural image sequences constrain dynamic receptive fields and imply a sparse code.

    Science.gov (United States)

    Häusler, Chris; Susemihl, Alex; Nawrot, Martin P

    2013-11-06

    In their natural environment, animals experience a complex and dynamic visual scenery. Under such natural stimulus conditions, neurons in the visual cortex employ a spatially and temporally sparse code. For the input scenario of natural still images, previous work demonstrated that unsupervised feature learning combined with the constraint of sparse coding can predict physiologically measured receptive fields of simple cells in the primary visual cortex. This convincingly indicated that the mammalian visual system is adapted to the natural spatial input statistics. Here, we extend this approach to the time domain in order to predict dynamic receptive fields that can account for both spatial and temporal sparse activation in biological neurons. We rely on temporal restricted Boltzmann machines and suggest a novel temporal autoencoding training procedure. When tested on a dynamic multi-variate benchmark dataset this method outperformed existing models of this class. Learning features on a large dataset of natural movies allowed us to model spatio-temporal receptive fields for single neurons. They resemble temporally smooth transformations of previously obtained static receptive fields and are thus consistent with existing theories. A neuronal spike response model demonstrates how the dynamic receptive field facilitates temporal and population sparseness. We discuss the potential mechanisms and benefits of a spatially and temporally sparse representation of natural visual input. Copyright © 2013 The Authors. Published by Elsevier B.V. All rights reserved.

  5. Does Disparity in the Way Disabled Older Adults Are Treated Imply Ageism?

    Science.gov (United States)

    Kane, Robert L.; Priester, Reinhard; Neumann, Dean

    2007-01-01

    Although the nearly one in seven Americans who have disabilities share many characteristics, the attitudes toward and the programs, care models, expenditures, and goals for people with disabilities differ substantially across age groups in ways that suggest ageism. Expenditures per recipient are substantially higher for younger individuals with…

  6. Biofilms in vitro and in vivo: do singular mechanisms imply cross-resistance?

    Science.gov (United States)

    Gilbert, P; Allison, D G; McBain, A J

    2002-01-01

    Microbial biofilm has become inexorably linked with man's failure to control them by antibiotic and biocide regimes that are effective against suspended bacteria. This failure relates to a localized concentration of biofilm bacteria, and their extracellular products (exopolymers and extracellular enzymes), that moderates the access of the treatment agent and starves the more deeply placed cells. Biofilms, therefore, typically present gradients of physiology and concentration for the imposed treatment agent, which enables the less susceptible clones to survive. Such clones might include efflux mutants in addition to genotypes with modifications in single gene products. Clonal expansion following subeffective treatment would, in the case of many antibiotics, lead to the emergence of a resistant population. This tends not to occur for biocidal treatments where the active agent exhibits multiple pharmacological activity towards a number of specific cellular targets. Whilst resistance development towards biocidal agents is highly unlikely, subeffective exposure will lead to the selection of less susceptible clones, modified either in efflux or in their most susceptible target. The latter might also confer resistance to antibiotics where the target is shared. Thus, recent reports have demonstrated that sublethal concentrations of the antibacterial and antifungal agent triclosan can select for resistant mutants in Escherichia coli and that this agent specifically targets the enzyme enoyl reductase that is involved in lipid biosynthesis. Triclosan may, therefore, select for mutants in a target that is shared with the anti-E. coli diazaborine compounds and the antituberculosis drug isoniazid. Although triclosan may be a uniquely specific biocide, sublethal concentrations of less specific antimicrobial agents may also select for mutations within their most sensitive targets, some of which might be common to therapeutic agents. Sublethal treatment with chemical antimicrobial agents has also been demonstrated to induce the expression of multidrug efflux pumps and efflux mutants. Whilst efflux does not confer protection against use concentrations of biocidal products it is sufficient to confer protection against therapeutic doses of many antibiotics. It has, therefore, been widely speculated that biocide misuse may have an insidious effect, contributing to the evolution and persistence of drug resistance within microbial communities. Whilst such notions are supported by laboratory studies that utilize pure cultures, recent evidence has strongly refuted such linkage within the general environment where complex, multispecies biofilms predominate and where biocidal products are routinely deployed. In such situations the competition, for nutrients and space, between community members of disparate sensitivities far outweighs any potential benefits bestowed by the changes in an individual's antimicrobial susceptibility.

  7. P-T data from central Bhutan imply distributed extensional shear at the Black Mountain "klippe"

    Science.gov (United States)

    Corrie, S. L.; Kohn, M. J.; Long, S. P.; McQuarrie, N.; Tobgay, T.

    2011-12-01

    The Southern Tibetan Detachment system (STDS) occurs along the entire length of the Himalayan orogen, and extensionally emplaces low-grade to unmetamorphosed Tethyan Himalayan (TH) rocks over highly metamorphosed Greater Himalayan sequence (GH) rocks. The base of TH remnants preserved in northern Bhutan all have top-to-the-north shear sense indicators (C'-type shear bands, asymmetric folds, and boudinaged leucogranite dikes) that are interpreted to reflect a discrete shear zone. In contrast, the GH-TH contact in the southernmost TH remnant (the Black Mountain region, central Bhutan) has been interpreted as depositional. A depositional contact limits the magnitude of displacement along the early STDS to 10's of km. If the GH-TH contact in the Black Mountain region is instead a discrete shear zone, as observed farther north, displacement on the STDS could be as high as 100's of km. To discriminate between these two interpretations, we determined peak metamorphic P-T conditions through the GH and TH sections, reasoning that a discrete shear zone would produce a distinct jump in metamorphic temperature, pressure or both. Thin section-scale kinematic indicators reveal pervasive top-to-the-north shear from 2-3 km structurally above the Main Central thrust (MCT) through the rest of the 11 km thick GH and TH sections. P-T conditions were determined from immediately above the MCT to 4 km above the GH-TH contact, with 19 samples from the GH, 6 from the overlying Chekha Fm (TH), and 9 from the overlying Maneting Fm (TH). We applied standard Fe-Mg exchange thermometers and Ca net-transfer barometers involving garnet. P-T conditions range from 700 °C and 11 kbar in migmatitic GHS to 600 °C and 8 kbar at the GH-Chekha contact, and 500 °C and 5 kbar at the top of the Maneting. We found no jumps in either temperature or pressure at any level, but a steeper than lithostatic pressure gradient, which we interpret to result from distributed extensional shear. The average thermal field gradient is surprisingly cool - only 20-25 °C/km. The baric field gradient is approximately 2 times steeper than lithostatic - 0.6 to 0.7 kbar/km, rather than 0.3 - so approximately 10 km of section has been excised. We argue that instead of a discrete structure, the Black Mountain "klippe," is part of a broad (≥8 km thick), low displacement shear zone and that the relationship between the GH and TH rocks in this region is depositional. These results support relatively minor displacement (a few tens of km) on the STDS remnants in northern Bhutan. Thus while channel- like behavior is present within the GHS and TH sections, its role in controlling Himalayan architecture is minor.

  8. Fractional Black-Scholes option pricing, volatility calibration and implied Hurst exponents in South African context

    OpenAIRE

    Flint, Emlyn; Maré, Eben

    2017-01-01

    Background: Contingent claims on underlying assets are typically priced under a framework that assumes, inter alia, that the log returns of the underlying asset are normally distributed. However, many researchers have shown that this assumption is violated in practice. Such violations include the statistical properties of heavy tails, volatility clustering, leptokurtosis and long memory. This paper considers the pricing of contingent claims when the underlying is assumed to display long memor...

  9. The Continued Influence of Implied and Explicitly Stated Misinformation in News Reports

    Science.gov (United States)

    Rich, Patrick R.; Zaragoza, Maria S.

    2016-01-01

    The piecemeal reporting of unfolding news events can lead to the reporting of mistaken information (or misinformation) about the cause of the newsworthy event, which later needs to be corrected. Studies of the "continued influence effect" have shown, however, that corrections are not entirely effective in reversing the effects of initial…

  10. 77 FR 2056 - Merrimac Paper Company, Inc.; Notice of Termination of License by Implied Surrender and...

    Science.gov (United States)

    2012-01-13

    ... DEPARTMENT OF ENERGY Federal Energy Regulatory Commission [Project No. 2928-007] Merrimac Paper.... Date Initiated: January 06, 2012. d. Licensee: Merrimac Paper Company, Inc. e. Name and Location of... Internet in lieu of paper. See 18 CFR 385.2001(a)(1)(iii) and the instructions on the Commission's Web site...

  11. The dominance of introspective measures and what this implies: The example of environmental attitude.

    Science.gov (United States)

    Otto, Siegmar; Kröhne, Ulf; Richter, David

    2018-01-01

    The behavioral sciences, including most of psychology, seek to explain and predict behavior with the help of theories and models that involve concepts (e.g., attitudes) that are subsequently translated into measures. Currently, some subdisciplines such as social psychology focus almost exclusively on measures that demand reflection or even introspection when administered to persons. We argue that such a focus hinders progress in explaining behavior. One major reason is that such an exclusive focus on reflections results in common method bias, which then produces spurious relations, or in other words, low discriminant validity. Without the valid measurement of theoretical concepts, theoretical assumptions cannot be tested, and hence, theory development will be hampered. We argue that the use of a greater variety of methods would reduce these problems and would in turn foster theory building. Using a representative sample of N = 472 participants (age: M = 51.0, SD = 17.7; 54% female), we compared the validity of a classical introspective attitude measure (i.e., the New Ecological Paradigm) with that of an alternative attitude measure (i.e., the General Ecological Behavior scale). The latter measure, which was based on self-reported behavior, showed substantially better validity that we argue could aid theory development.

  12. Effects of ionizing radiation on plants and animals at levels implied by current radiation protection standards

    International Nuclear Information System (INIS)

    1992-01-01

    The 1977 Recommendations of the International Commission on Radiological Protection stated that the commission believes that if man is adequately protected from radiation, other organisms are also likely to be sufficiently protected. The present report examines this statement by considering the effects of ionizing radiation on animals and plants in both terrestrial and aquatic ecosystems. The conclusions are that chronic dose rates of IMGy.d -1 or less are unlikely to cause measurable deleterious effects in terrestrial populations, and that in the aquatic environment limiting chronic dose rates to 10MGy.d -1 to the maximally exposed individuals would provide adequate protection for the population. Thus specific radiation protection standards for non-human organisms are not needed. 193 refs, 2 figs, 7 tabs

  13. Density forecasts of crude-oil prices using option-implied and ARCH-type models

    DEFF Research Database (Denmark)

    Høg, Esben; Tsiaras, Leonicas

    2011-01-01

    of derivative contracts. Risk-neutral densities, obtained from panels of crude-oil option prices, are adjusted to reflect real-world risks using either a parametric or a non-parametric calibration approach. The relative performance of the models is evaluated for the entire support of the density, as well...... obtained by option prices and non-parametric calibration methods over those constructed using historical returns and simulated ARCH processes. © 2010 Wiley Periodicals, Inc. Jrl Fut Mark...

  14. Nonstandard gravitational waves imply gravitational slip: on the difficulty of partially hiding new gravitational degrees of freedom

    Czech Academy of Sciences Publication Activity Database

    Sawicki, Ignacy; Saltas, I.D.; Motta, M.; Amendola, L.; Kunz, M.

    2017-01-01

    Roč. 95, č. 8 (2017), s. 1-16, č. článku 083520. ISSN 2470-0010 R&D Projects: GA MŠk EF15_003/0000437 Grant - others:OP VVV - CoGraDS(XE) CZ.02.1.01/0.0/0.0/15_003/0000437 Institutional support: RVO:68378271 Keywords : modified gravity * gravitational waves * cosmology * large scale structure Subject RIV: BN - Astronomy, Celestial Mechanics, Astrophysics OBOR OECD: Astronomy (including astrophysics,space science) Impact factor: 4.568, year: 2016

  15. "Modern" Education Finance: How It Differs from the "Old" and the Analytic and Data Collection Changes It Implies

    Science.gov (United States)

    Guthrie, James W.

    2006-01-01

    This article contends that a new concept of education finance has emerged in response to substantial alterations in the U.S. education policy environment. The major distinction between modern and old is that the latter was principally concerned with arrangements of inputs in K-12 schooling. The former, modern-era education finance, is concerned…

  16. WNK1 and p38-MAPK distribution in ionocytes and accessory cells of euryhaline teleost fish implies ionoregulatory function

    Directory of Open Access Journals (Sweden)

    W. S. Marshall

    2017-07-01

    Full Text Available Ionocytes of euryhaline teleost fish secrete NaCl, under regulation by serine and threonine kinases, including with-no-lysine kinase (WNK1 and p38 mitogen-activated protein kinase (MAPK. Mummichogs (Fundulus heteroclitus L. were acclimated to freshwater (FW, full strength seawater (SW and hypersaline conditions (2SW. Immunocytochemistry of ionocytes in opercular epithelia of fish acclimated to SW and 2SW revealed that WNK1-anti-pT58 phosphoantibody localized strongly to accessory cells and was present in the cytosol of ionocytes, close to cystic fibrosis transmembrane conductance regulator (CFTR in the apical membrane and the sodium potassium 2 chloride cotransporter (NKCC in the basolateral membrane. In FW acclimated fish, WNK1 localized to a sub-apical zone, did not colocalize with apical membrane-located sodium chloride cotransporter (NCC, and typically was present in one cell of paired ionocytes and in some single ionocytes. Forskolin treatment (10 μM, 30 min increased WNK1 immunofluorescence in SW ionocytes only, while hypertonicity had little effect, compared to controls. Anti-p38-MAPK antibody localized to the cytosolic compartment. The distribution of WNK1 and p38MAPK is consistent with a proximal position in regulatory cascades, rather than directly affecting transporters. The strong staining of accessory cells by WNK1 phosphoantibody infers an osmoregulatory function for WNK.

  17. Global outlook for wood and forests with the bioenergy demand implied by scenarios of the intergovernmental panel on climate change

    Science.gov (United States)

    Ronald Raunikar; Joseph Buongiorno; James A. Turner; Shushuai Zhu

    2010-01-01

    The Global Forest Products Model (GFPM) was modified to link the forest sector to two scenarios of the Intergovernmental Panel on Climate Change (IPCC), and to represent the utilization of fuelwood and industrial roundwood to produce biofuels. The scenarios examined were a subset of the “story lines” prepared by the IPCC. Each scenario has projections of population and...

  18. Meta-analysis of high-latitude nitrogen-addition and warming studies implies ecological mechanisms overlooked by land models

    Science.gov (United States)

    Bouskill, N. J.; Riley, W. J.; Tang, J. Y.

    2014-12-01

    Accurate representation of ecosystem processes in land models is crucial for reducing predictive uncertainty in energy and greenhouse gas feedbacks with the climate. Here we describe an observational and modeling meta-analysis approach to benchmark land models, and apply the method to the land model CLM4.5 with two versions of belowground biogeochemistry. We focused our analysis on the aboveground and belowground responses to warming and nitrogen addition in high-latitude ecosystems, and identified absent or poorly parameterized mechanisms in CLM4.5. While the two model versions predicted similar soil carbon stock trajectories following both warming and nitrogen addition, other predicted variables (e.g., belowground respiration) differed from observations in both magnitude and direction, indicating that CLM4.5 has inadequate underlying mechanisms for representing high-latitude ecosystems. On the basis of observational synthesis, we attribute the model-observation differences to missing representations of microbial dynamics, aboveground and belowground coupling, and nutrient cycling, and we use the observational meta-analysis to discuss potential approaches to improving the current models. However, we also urge caution concerning the selection of data sets and experiments for meta-analysis. For example, the concentrations of nitrogen applied in the synthesized field experiments (average = 72 kg ha-1 yr-1) are many times higher than projected soil nitrogen concentrations (from nitrogen deposition and release during mineralization), which precludes a rigorous evaluation of the model responses to likely nitrogen perturbations. Overall, we demonstrate that elucidating ecological mechanisms via meta-analysis can identify deficiencies in ecosystem models and empirical experiments.

  19. Meta-analysis of high-latitude nitrogen-addition and warming studies imply ecological mechanisms overlooked by land models

    Science.gov (United States)

    Bouskill, N. J.; Riley, W. J.; Tang, J.

    2014-08-01

    Accurate representation of ecosystem processes in land models is crucial for reducing predictive uncertainty in energy and greenhouse gas feedbacks with the atmosphere. Here we describe an observational and modeling meta-analysis approach to benchmark land models, and apply the method to the land model CLM4.5 with two versions of belowground biogeochemistry. We focused our analysis on the above and belowground high-latitude ecosystem responses to warming and nitrogen addition, and identified mechanisms absent, or poorly parameterized in CLM4.5. While the two model versions predicted similar trajectories for soil carbon stocks following both types of perturbation, other variables (e.g., belowground respiration) differed from the observations in both magnitude and direction, indicating the underlying mechanisms are inadequate for representing high-latitude ecosystems. The observational synthesis attribute these differences to missing representations of microbial dynamics, characterization of above and belowground functional processes, and nutrient competition. We use the observational meta-analyses to discuss potential approaches to improving the current models (e.g., the inclusion of dynamic vegetation or different microbial functional guilds), however, we also raise a cautionary note on the selection of data sets and experiments to be included in a meta-analysis. For example, the concentrations of nitrogen applied in the synthesized field experiments (average =72 kg ha-1 yr-1) are many times higher than projected soil nitrogen concentrations (from nitrogen deposition and release during mineralization), which preclude a rigorous evaluation of the model responses to nitrogen perturbation. Overall, we demonstrate here that elucidating ecological mechanisms via meta-analysis can identify deficiencies in both ecosystem models and empirical experiments.

  20. Do Higher Fees Imply Better Performance? An Insight to Fee-performance Relationship in the US Mutual Fund Industry.

    OpenAIRE

    FAN, YI

    2008-01-01

    Recent studies propose that equity mutual fund managers generally do not have ability to generate abnormal returns to outperform the market, and their performance bear negative relationship with the expenses charged when investors invest in mutual funds. This study employs a data set including monthly returns from sixty equity mutual funds existing throughout the examined period from January 1998 to December 2007. These data are used to examine performance of actively managed mutual funds and...

  1. View-tolerant face recognition and Hebbian learning imply mirror-symmetric neural tuning to head orientation

    Science.gov (United States)

    Leibo, Joel Z.; Liao, Qianli; Freiwald, Winrich A.; Anselmi, Fabio; Poggio, Tomaso

    2017-01-01

    SUMMARY The primate brain contains a hierarchy of visual areas, dubbed the ventral stream, which rapidly computes object representations that are both specific for object identity and robust against identity-preserving transformations like depth-rotations [1, 2]. Current computational models of object recognition, including recent deep learning networks, generate these properties through a hierarchy of alternating selectivity-increasing filtering and tolerance-increasing pooling operations, similar to simple-complex cells operations [3, 4, 5, 6]. Here we prove that a class of hierarchical architectures and a broad set of biologically plausible learning rules generate approximate invariance to identity-preserving transformations at the top level of the processing hierarchy. However, all past models tested failed to reproduce the most salient property of an intermediate representation of a three-level face-processing hierarchy in the brain: mirror-symmetric tuning to head orientation [7]. Here we demonstrate that one specific biologically-plausible Hebb-type learning rule generates mirror-symmetric tuning to bilaterally symmetric stimuli like faces at intermediate levels of the architecture and show why it does so. Thus the tuning properties of individual cells inside the visual stream appear to result from group properties of the stimuli they encode and to reflect the learning rules that sculpted the information-processing system within which they reside. PMID:27916522

  2. Author Correction: Discovery of rapid whistlers close to Jupiter implying lightning rates similar to those on Earth

    Science.gov (United States)

    Kolmašová, Ivana; Imai, Masafumi; Santolík, Ondřej; Kurth, William S.; Hospodarsky, George B.; Gurnett, Donald A.; Connerney, John E. P.; Bolton, Scott J.

    2018-06-01

    In the version of this Letter originally published, in the second sentence of the last paragraph before the Methods section the word `altitudes' was mistakenly used in place of the word `latitudes'. The sentence has now been corrected accordingly to: `Low-dispersion class 1 events indicate that low-density ionospheric regions predominantly occur in the northern hemisphere at latitudes between 20° and 70°.'

  3. Decidual-secreted factors alter invasive trophoblast membrane and secreted proteins implying a role for decidual cell regulation of placentation.

    Directory of Open Access Journals (Sweden)

    Ellen Melaleuca Menkhorst

    Full Text Available Inadequate or inappropriate implantation and placentation during the establishment of human pregnancy is thought to lead to first trimester miscarriage, placental insufficiency and other obstetric complications. To create the placental blood supply, specialized cells, the 'extravillous trophoblast' (EVT invade through the differentiated uterine endometrium (the decidua to engraft and remodel uterine spiral arteries. We hypothesized that decidual factors would regulate EVT function by altering the production of EVT membrane and secreted factors. We used a proteomics approach to identify EVT membrane and secreted proteins regulated by decidual cell factors. Human endometrial stromal cells were decidualized in vitro by treatment with estradiol (10(-8 M, medroxyprogesterone acetate (10(-7 M and cAMP (0.5 mM for 14 days. Conditioned media (CM was collected on day 2 (non-decidualized CM and 14 (decidualized CM of treatment. Isolated primary EVT cultured on Matrigel™ were treated with media control, non-decidualized or decidualized CM for 16 h. EVT CM was fractionated for proteins <30 kDa using size-exclusion affinity nanoparticles (SEAN before trypsin digestion and HPLC-MS/MS. 43 proteins produced by EVT were identified; 14 not previously known to be expressed in the placenta and 12 which had previously been associated with diseases of pregnancy including preeclampsia. Profilin 1, lysosome associated membrane glycoprotein 1 (LAMP1, dipeptidyl peptidase 1 (DPP1/cathepsin C and annexin A2 expression by interstitial EVT in vivo was validated by immunhistochemistry. Decidual CM regulation in vitro was validated by western blotting: decidualized CM upregulated profilin 1 in EVT CM and non-decidualized CM upregulated annexin A2 in EVT CM and pro-DPP1 in EVT cell lysate. Here, non-decidualized factors induced protease expression by EVT suggesting that non-decidualized factors may induce a pro-inflammatory cascade. Preeclampsia is a pro-inflammatory condition. Overall, we have demonstrated the potential of a proteomics approach to identify novel proteins expressed by EVT and to uncover the mechanisms leading to disease states.

  4. A Comparative Analysis of the Ethos, Role and Function of Implied Obligations in Shipping Law and General Law of Contract

    OpenAIRE

    Ndi, George; Alawneh, Tariq

    2015-01-01

    The law governing the international carriage of goods by sea is deeply rooted in the doctrine of freedom of contract. The historical origins of the shipping industry itself can be traced to the era of 'laissez faire' in which contractual practice, based on negotiated terms and conditions, was free from the regulatory constraints of the state. It is for this reason that to this day modern shipping law is still rooted in the common law and customary trade usages with very limited statutory infl...

  5. What do farmers' weed control decisions imply about glyphosate resistance? Evidence from surveys of US corn fields.

    Science.gov (United States)

    Wechsler, Seth J; McFadden, Jonathan R; Smith, David J

    2018-05-01

    The first case of glyphosate-resistant weeds in the United States was documented in 1998, 2 years after the commercialization of genetically engineered herbicide-resistant (HR) corn and soybeans. Currently, over 15 glyphosate-resistant weed species affect US crop production areas. These weeds have the potential to reduce yields, increase costs, and lower farm profitability. The objective of our study is to develop a behavioral model of farmers' weed management decisions and use it to analyze weed resistance to glyphosate in US corn farms. On average, we find that weed control increased US corn yields by 3700 kg ha -1 (worth approximately $US 255 ha -1 ) in 2005 and 3500 kg ha -1 (worth approximately $US 575 ha -1 ) in 2010. If glyphosate resistant weeds were absent, glyphosate killed approximately 99% of weeds, on average, when applied at the label rate in HR production systems. Average control was dramatically lower in states where glyphosate resistance was widespread. We find that glyphosate resistance had a significant impact on weed control costs and corn yields of US farmers in 2005 and 2010. Published 2017. This article is a U.S. Government work and is in the public domain in the USA. Published 2017. This article is a U.S. Government work and is in the public domain in the USA.

  6. Accumulation of Fe oxyhydroxides in the Peruvian oxygen deficient zone implies non-oxygen dependent Fe oxidation

    Science.gov (United States)

    Heller, Maija I.; Lam, Phoebe J.; Moffett, James W.; Till, Claire P.; Lee, Jong-Mi; Toner, Brandy M.; Marcus, Matthew A.

    2017-08-01

    Oxygen minimum zones (OMZs) have been proposed to be an important source of dissolved iron (Fe) into the interior ocean. However, previous studies in OMZs have shown a sharp decrease in total dissolved Fe (dFe) and/or dissolved Fe(II) (dFe(II)) concentrations at the shelf-break, despite constant temperature, salinity and continued lack of oxygen across the shelf-break. The loss of both total dFe and dFe(II) suggests a conversion of the dFe to particulate form, but studies that have coupled the reduction-oxidation (redox) speciation of both dissolved and particulate phases have not previously been done. Here we have measured the redox speciation and concentrations of both dissolved and particulate forms of Fe in samples collected during the U.S. GEOTRACES Eastern tropical Pacific Zonal Transect (EPZT) cruise in 2013 (GP16). This complete data set allows us to assess possible mechanisms for loss of dFe. We observed an offshore loss of dFe(II) within the oxygen deficient zone (ODZ), where dissolved oxygen is undetectable, accompanied by an increase in total particulate Fe (pFe). Total pFe concentrations were highest in the upper ODZ. X-ray absorption spectroscopy revealed that the pFe maximum was primarily in the Fe(III) form as Fe(III) oxyhydroxides. The remarkable similarity in the distributions of total particulate iron and nitrite suggests a role for nitrite in the oxidation of dFe(II) to pFe(III). We present a conceptual model for the rapid redox cycling of Fe that occurs in ODZs, despite the absence of oxygen.

  7. Evolution of biological sequences implies an extreme value distribution of type I for both global and local pairwise alignment scores.

    Science.gov (United States)

    Bastien, Olivier; Maréchal, Eric

    2008-08-07

    Confidence in pairwise alignments of biological sequences, obtained by various methods such as Blast or Smith-Waterman, is critical for automatic analyses of genomic data. Two statistical models have been proposed. In the asymptotic limit of long sequences, the Karlin-Altschul model is based on the computation of a P-value, assuming that the number of high scoring matching regions above a threshold is Poisson distributed. Alternatively, the Lipman-Pearson model is based on the computation of a Z-value from a random score distribution obtained by a Monte-Carlo simulation. Z-values allow the deduction of an upper bound of the P-value (1/Z-value2) following the TULIP theorem. Simulations of Z-value distribution is known to fit with a Gumbel law. This remarkable property was not demonstrated and had no obvious biological support. We built a model of evolution of sequences based on aging, as meant in Reliability Theory, using the fact that the amount of information shared between an initial sequence and the sequences in its lineage (i.e., mutual information in Information Theory) is a decreasing function of time. This quantity is simply measured by a sequence alignment score. In systems aging, the failure rate is related to the systems longevity. The system can be a machine with structured components, or a living entity or population. "Reliability" refers to the ability to operate properly according to a standard. Here, the "reliability" of a sequence refers to the ability to conserve a sufficient functional level at the folded and maturated protein level (positive selection pressure). Homologous sequences were considered as systems 1) having a high redundancy of information reflected by the magnitude of their alignment scores, 2) which components are the amino acids that can independently be damaged by random DNA mutations. From these assumptions, we deduced that information shared at each amino acid position evolved with a constant rate, corresponding to the information hazard rate, and that pairwise sequence alignment scores should follow a Gumbel distribution, which parameters could find some theoretical rationale. In particular, one parameter corresponds to the information hazard rate. Extreme value distribution of alignment scores, assessed from high scoring segments pairs following the Karlin-Altschul model, can also be deduced from the Reliability Theory applied to molecular sequences. It reflects the redundancy of information between homologous sequences, under functional conservative pressure. This model also provides a link between concepts of biological sequence analysis and of systems biology.

  8. Evolution of biological sequences implies an extreme value distribution of type I for both global and local pairwise alignment scores

    Directory of Open Access Journals (Sweden)

    Maréchal Eric

    2008-08-01

    Full Text Available Abstract Background Confidence in pairwise alignments of biological sequences, obtained by various methods such as Blast or Smith-Waterman, is critical for automatic analyses of genomic data. Two statistical models have been proposed. In the asymptotic limit of long sequences, the Karlin-Altschul model is based on the computation of a P-value, assuming that the number of high scoring matching regions above a threshold is Poisson distributed. Alternatively, the Lipman-Pearson model is based on the computation of a Z-value from a random score distribution obtained by a Monte-Carlo simulation. Z-values allow the deduction of an upper bound of the P-value (1/Z-value2 following the TULIP theorem. Simulations of Z-value distribution is known to fit with a Gumbel law. This remarkable property was not demonstrated and had no obvious biological support. Results We built a model of evolution of sequences based on aging, as meant in Reliability Theory, using the fact that the amount of information shared between an initial sequence and the sequences in its lineage (i.e., mutual information in Information Theory is a decreasing function of time. This quantity is simply measured by a sequence alignment score. In systems aging, the failure rate is related to the systems longevity. The system can be a machine with structured components, or a living entity or population. "Reliability" refers to the ability to operate properly according to a standard. Here, the "reliability" of a sequence refers to the ability to conserve a sufficient functional level at the folded and maturated protein level (positive selection pressure. Homologous sequences were considered as systems 1 having a high redundancy of information reflected by the magnitude of their alignment scores, 2 which components are the amino acids that can independently be damaged by random DNA mutations. From these assumptions, we deduced that information shared at each amino acid position evolved with a constant rate, corresponding to the information hazard rate, and that pairwise sequence alignment scores should follow a Gumbel distribution, which parameters could find some theoretical rationale. In particular, one parameter corresponds to the information hazard rate. Conclusion Extreme value distribution of alignment scores, assessed from high scoring segments pairs following the Karlin-Altschul model, can also be deduced from the Reliability Theory applied to molecular sequences. It reflects the redundancy of information between homologous sequences, under functional conservative pressure. This model also provides a link between concepts of biological sequence analysis and of systems biology.

  9. PERSPECTIVES OF TEACHER TRAINING AND INITIAL LITERACY IMPLIED IN EDUCATIONAL PROGRAMS OF THE NORMAL SCHOOLS OF MEXICO

    Directory of Open Access Journals (Sweden)

    Efrén Viramontes Anaya

    2013-09-01

    Full Text Available Introduction. The stage or phase of this research project is intended to perform an analysis of approaches for teacher ́s training and early literacy of current language programs in Mexico ́s teacher education. The central con-tent of the document contains the analysis of approaches of teachers ́ trai-ning and initial literacy that lie behind educational programs. The theoretical approach is supported by Pérez Gómez (1996 and in the field of literacy in Ferreiro and Teberobsky (2007 and Lerner (2001. The research methodology is projected into the reconstructive critical pa-radigm as a diagnostic part of a future participative action research that will be conducted in two remaining stages. The perspective of analysis is established by the methodological contributions of Habermas (2008, in the hermeneutic reconstruction of implicit in the analyzed documents approaches. The results and discussion of them that provide lines of analysis of educa-tional programs, the relationship between theory and practice in curriculum approaches and a proposal of teachers profile requirements of language courses for teaching training as well as suggestions for future restructuring of curricula for teacher ́s colleges. In the conclusion, it is established that the perspective and the teacher training approach identified in the curriculum of Primary Education Degree (1997 and 2012 Preschool Education Degree (1999 and 2012 is mainly a model technical decision-making. This explains that the formative processes in teaching students of Tea-chers colleges , there is a tendency to engage in activities that are based on the theory, performing analytical processes that lead to understand the di-dactical principles of approaches for teaching reading instruction and writing, which will be applied in decision-making processes in situ of teaching practi-ce. Initial literacy approaches identified in the curriculum of Elementary and Preschool Degrees 1997 and 1999 plans, they have a strong tendency in the fundamentals of psychogenetic teaching and reading and writing learning, which is based on knowledge of the individual processes that children follow in a evolutionary way in the comprehension of the writing system. On the other hand, 2012 educational programs for both degrees have behind them as priority way the sociolinguistic approach, based on the social practices of the language, including also a fair part where is necessary in, psychogenetic approach.

  10. PERSPECTIVES OF TEACHER TRAINING AND INITIAL LITERACY IMPLIED IN EDUCATIONAL PROGRAMS OF THE NORMAL SCHOOLS OF MEXICO

    OpenAIRE

    Efrén Viramontes Anaya; Marivel Gutiérrez Fierro; y Luz Divina Núñez Si-fuentes

    2013-01-01

    Introduction. The stage or phase of this research project is intended to perform an analysis of approaches for teacher ́s training and early literacy of current language programs in Mexico ́s teacher education. The central con-tent of the document contains the analysis of approaches of teachers ́ trai-ning and initial literacy that lie behind educational programs. The theoretical approach is supported by Pérez Gómez (1996) and in the field of literacy in Ferreiro and Teberobsky (2007) and...

  11. Industry 4.0 implies lean manufacturing: research activities in industry 4.0 function as enablers for lean manufacturing

    OpenAIRE

    Sanders, Adam; Elangeswaran, Chola; Wulfsberg, Jens

    2016-01-01

    Purpose: Lean Manufacturing is widely regarded as a potential methodology to improve productivity and decrease costs in manufacturing organisations. The success of lean manufacturing demands consistent and conscious efforts from the organisation, and has to overcome several hindrances. Industry 4.0 makes a factory smart by applying advanced information and communication systems and future-oriented technologies. This paper analyses the incompletely perceived link between Industr...

  12. Semi-discrete approximations to nonlinear systems of conservation laws; consistency and L(infinity)-stability imply convergence. Final report

    International Nuclear Information System (INIS)

    Tadmor, E.

    1988-07-01

    A convergence theory for semi-discrete approximations to nonlinear systems of conservation laws is developed. It is shown, by a series of scalar counter-examples, that consistency with the conservation law alone does not guarantee convergence. Instead, a notion of consistency which takes into account both the conservation law and its augmenting entropy condition is introduced. In this context it is concluded that consistency and L(infinity)-stability guarantee for a relevant class of admissible entropy functions, that their entropy production rate belongs to a compact subset of H(loc)sup -1 (x,t). One can now use compensated compactness arguments in order to turn this conclusion into a convergence proof. The current state of the art for these arguments includes the scalar and a wide class of 2 x 2 systems of conservation laws. The general framework of the vanishing viscosity method is studied as an effective way to meet the consistency and L(infinity)-stability requirements. How this method is utilized to enforce consistency and stability for scalar conservation laws is shown. In this context we prove, under the appropriate assumptions, the convergence of finite difference approximations (e.g., the high resolution TVD and UNO methods), finite element approximations (e.g., the Streamline-Diffusion methods) and spectral and pseudospectral approximations (e.g., the Spectral Viscosity methods)

  13. Do Increasing Rates of Loss to Follow-up in Antiretroviral Treatment Programs Imply Deteriorating Patient Retention?

    Science.gov (United States)

    Johnson, Leigh F.; Estill, Janne; Keiser, Olivia; Cornell, Morna; Moolla, Haroon; Schomaker, Michael; Grimsrud, Anna; Davies, Mary-Ann; Boulle, Andrew

    2014-01-01

    In several studies of antiretroviral treatment (ART) programs for persons with human immunodeficiency virus infection, investigators have reported that there has been a higher rate of loss to follow-up (LTFU) among patients initiating ART in recent years than among patients who initiated ART during earlier time periods. This finding is frequently interpreted as reflecting deterioration of patient retention in the face of increasing patient loads. However, in this paper we demonstrate by simulation that transient gaps in follow-up could lead to bias when standard survival analysis techniques are applied. We created a simulated cohort of patients with different dates of ART initiation. Rates of ART interruption, ART resumption, and mortality were assumed to remain constant over time, but when we applied a standard definition of LTFU, the simulated probability of being classified LTFU at a particular ART duration was substantially higher in recently enrolled cohorts. This suggests that much of the apparent trend towards increased LTFU may be attributed to bias caused by transient interruptions in care. Alternative statistical techniques need to be used when analyzing predictors of LTFU—for example, using “prospective” definitions of LTFU in place of “retrospective” definitions. Similar considerations may apply when analyzing predictors of LTFU from treatment programs for other chronic diseases. PMID:25399412

  14. Industry 4.0 implies lean manufacturing: Research activities in industry 4.0 function as enablers for lean manufacturing

    Directory of Open Access Journals (Sweden)

    Adam Sanders

    2016-09-01

    Full Text Available Purpose: Lean Manufacturing is widely regarded as a potential methodology to improve productivity and decrease costs in manufacturing organisations. The success of lean manufacturing demands consistent and conscious efforts from the organisation, and has to overcome several hindrances. Industry 4.0 makes a factory smart by applying advanced information and communication systems and future-oriented technologies. This paper analyses the incompletely perceived link between Industry 4.0 and lean manufacturing, and investigates whether Industry 4.0 is capable of implementing lean. Executing Industry 4.0 is a cost-intensive operation, and is met with reluctance from several manufacturers. This research also provides an important insight into manufacturers’ dilemma as to whether they can commit into Industry 4.0, considering the investment required and unperceived benefits. Design/methodology/approach: Lean manufacturing is first defined and different dimensions of lean are presented. Then Industry 4.0 is defined followed by representing its current status in Germany. The barriers for implementation of lean are analysed from the perspective of integration of resources. Literatures associated with Industry 4.0 are studied and suitable solution principles are identified to solve the abovementioned barriers of implementing lean. Findings: It is identified that researches and publications in the field of Industry 4.0 held answers to overcome the barriers of implementation of lean manufacturing. These potential solution principles prove the hypothesis that Industry 4.0 is indeed capable of implementing lean. It uncovers the fact that committing into Industry 4.0 makes a factory lean besides being smart. Originality/value: Individual researches have been done in various technologies allied with Industry 4.0, but the potential to execute lean manufacturing was not completely perceived. This paper bridges the gap between these two realms, and identifies exactly which aspects of Industry 4.0 contribute towards respective dimensions of lean manufacturing.

  15. Enamel hypoplasia in deciduous teeth of great apes: do differences in defect prevalence imply differential levels of physiological stress?

    Science.gov (United States)

    Lukacs, J R

    1999-11-01

    This paper presents new data on enamel hypoplasia in the deciduous canine teeth of great apes. The enamel defect under consideration is known as localized hypoplasia of primary canines (LHPC), and is characterized by an area of thin or missing enamel on the labial surface of deciduous canine teeth (Skinner [1986a] Am. J. Phys. Anthropol. 69:59-69). Goals of this study are: 1) to determine if significant differences in the frequency of LHPC occur among three genera of great apes, and 2) to evaluate variation in LHPC prevalence among great apes as evidence of differential physiological stress. Infant and juvenile apes with deciduous teeth were examined at the Cleveland Museum of Natural History (n = 100) and at the Smithsonian Institution, National Museum of Natural History (n = 36). Deciduous teeth were observed under oblique incandescent light, with the naked eye and with a 10x hand lens. Enamel hypoplasia was scored using Federation Dentaire International (FDI)-Defects of Dental Enamel (DDE) standards. Hypoplasias were recorded by drawing defect location and size on a dental chart, and by measuring defect size and location with Helios needlepoint dial calipers. The prevalence of LHPC is reported by genus and sex, using two approaches: 1) the frequency of affected individuals-those having one or more deciduous canine teeth scored positive for LHPC; and 2) the number of canine teeth scored positive for LHPC as a percentage of all canine teeth observed. Variation in defect size and location will be described elsewhere. Localized hypoplasia of primary canine teeth was found in 62.5% of 128 individual apes, and in 45.5% of 398 great ape deciduous canines. As in humans, LHPC is the most common form of enamel hypoplasia in deciduous teeth of great apes, while LEH is rare or absent. The distribution and pattern of expression of LHPC in great apes is similar to that described in humans: side differences are not significant, but mandibular canines exhibit the defect two to five times more often than maxillary canine teeth. Differences in LHPC prevalence by sex are small and not significant. Intergeneric differences are large and non-random: chimpanzees (Pan) exhibit a significantly lower frequency of LHPC (22%, n = 50) by individual count, than either the orangutan (Pongo, 88.0%, n = 25) or the gorilla (Gorilla, 88.7%, n = 53). Tooth count prevalences exhibit a similar pattern of variation and are also statistically significant. These findings suggest that large bodied great apes (gorilla and orangutan) may be under greater physiological stress during perinatal and early postnatal development than the chimpanzee. The size, position, and timing of LHPC lesions are currently under analysis and may yield more insight into the etiological origin of this enamel defect. Copyright 1999 Wiley-Liss, Inc.

  16. Statistical visualization of the Earth's magnetotail based on Geotail data and the implied substorm model

    Directory of Open Access Journals (Sweden)

    S. Machida

    2009-03-01

    Full Text Available We investigated the temporal and spatial development of the near-Earth magnetotail during substorms based on multi-dimensional superposed-epoch analysis of Geotail data. The start time of the auroral break-up (t=0 of each substorm was determined from auroral data obtained by the Polar and IMAGE spacecraft. The key parameters derived from the plasma, magnetic-field, and electric-field data from Geotail were sorted by their meridional X(GSM–Z(proxy coordinates.

    The results show that the Poynting flux toward the plasma-sheet center starts at least 10 min before the substorm onset, and is further enhanced at X~−12 RE (Earth radii around 4 min before the onset. Simultaneously, large-amplitude fluctuations occurred, and earthward flows in the central plasma sheet between X~−11 RE and X~−19 RE and a duskward flow around X=−10 RE were enhanced. The total pressure starts to decrease around X=−16 RE about 4 min before the onset of the substorm. After the substorm onset, a notable dipolarization is observed and tailward flows commence, characterised by southward magnetic fields in the form of a plasmoid.

    We confirm various observable-parameter variations based on or predicted by the relevant substorm models; however, none of these can explain our results perfectly. Therefore, we propose a catapult (slingshot current-sheet relaxation model, in which an earthward convective flow produced by catapult current-sheet relaxation and a converted duskward flow near the Earth are enhanced through flow braking around 4 min before the substorm onset. These flows induce a ballooning instability or other instabilities, causing the observed current disruption. The formation of the magnetic neutral line is a natural consequence of the present model, because the relaxation of a highly stretched catapult current-sheet produces a very thin current at its tailward edge being surrounded by intense earthward and tailward magnetic fields which were formerly the off-equatorial lobe magnetic fields. This location is the boundary between a highly stressed catapult current sheet and a Harris-type current sheet characterized by little stress. In addition, the flows induced around the boundary toward the current-sheet center may enhance the formation of the magnetic neutral line and the efficiency of magnetic reconnection. After magnetic reconnection is induced, it plays a significant role in driving the substorm.

  17. Power Load from Collision Debris on the LHC Point 8 Insertion Magnets implied by the LHCB Luminosity Increase

    CERN Document Server

    Esposito, L S; Lechner, A; Mereghetti, A; Vlachoudis, V; Patapenka, A

    2013-01-01

    LHCb is aiming to upgrade its goal peak luminosity up to a value of 2 × 1033 cm−2 s−1 after LS2. We investigate the collision debris impact on the machine elements by extensive FLUKA simulations, showing that the present machine layout is substantially compatible with such a luminosity goal. In particular the installation of a TAS (Target Absorber of Secondaries, installed in front of the final focus Q1-Q3 quadrupole triplet in the LHC high luminosity insertions) turns out not to be necessary on the basis of the expected peak power deposition in the Q1 superconducting coils. A warm protection may be desirable to further reduce heat load and dose on the D2 recombination dipole, due to the absence of the TAN (Target Absorber of Neutrals, present in Point 1 and 5).

  18. Sediment bacterial community structures and their predicted functions implied the impacts from natural processes and anthropogenic activities in coastal area.

    Science.gov (United States)

    Su, Zhiguo; Dai, Tianjiao; Tang, Yushi; Tao, Yile; Huang, Bei; Mu, Qinglin; Wen, Donghui

    2018-06-01

    Coastal ecosystem structures and functions are changing under natural and anthropogenic influences. In this study, surface sediment samples were collected from disturbed zone (DZ), near estuary zone (NEZ), and far estuary zone (FEZ) of Hangzhou Bay, one of the most seriously polluted bays in China. The bacterial community structures and predicted functions varied significantly in different zones. Firmicutes were found most abundantly in DZ, highlighting the impacts of anthropogenic activities. Sediment total phosphorus was most influential on the bacterial community structures. Predicted by PICRUSt analysis, DZ significantly exceeded FEZ and NEZ in the subcategory of Xenobiotics Biodegradation and Metabolism; and DZ enriched all the nitrate reduction related genes, except nrfA gene. Seawater salinity and inorganic nitrogen, respectively as the representative natural and anthropogenic factor, performed exact-oppositely in nitrogen metabolism functions. The changes of bacterial community compositions and predicted functions provide a new insight into human-induced pollution impacts on coastal ecosystem. Copyright © 2018 Elsevier Ltd. All rights reserved.

  19. Interaction between the C-terminal domains of measles virus nucleoprotein and phosphoprotein: a tight complex implying one binding site.

    Science.gov (United States)

    Blocquel, David; Habchi, Johnny; Costanzo, Stéphanie; Doizy, Anthony; Oglesbee, Michael; Longhi, Sonia

    2012-10-01

    The intrinsically disordered C-terminal domain (N(TAIL) ) of the measles virus (MeV) nucleoprotein undergoes α-helical folding upon binding to the C-terminal X domain (XD) of the phosphoprotein. The N(TAIL) region involved in binding coupled to folding has been mapped to a conserved region (Box2) encompassing residues 489-506. In the previous studies published in this journal, we obtained experimental evidence supporting a K(D) for the N(TAIL) -XD binding reaction in the nM range and also showed that an additional N(TAIL) region (Box3, aa 517-525) plays a role in binding to XD. In striking contrast with these data, studies published in this journal by Kingston and coworkers pointed out a much less stable complex (K(D) in the μM range) and supported lack of involvement of Box3 in complex formation. The objective of this study was to critically re-evaluate the role of Box3 in N(TAIL) -XD binding. Since our previous studies relied on N(TAIL) -truncated forms possessing an irrelevant Flag sequence appended at their C-terminus, we, herein, generated an N(TAIL) devoid of Box3 and any additional C-terminal residues, as well as a form encompassing only residues 482-525. We then used isothermal titration calorimetry to characterize the binding reactions between XD and these N(TAIL) forms. Results effectively argue for the presence of a single XD-binding site located within Box2, in agreement with the results by Kingston et al., while providing clear experimental support for a high-affinity complex. Altogether, the present data provide mechanistic insights into the replicative machinery of MeV and clarify a hitherto highly debated point. Copyright © 2012 The Protein Society.

  20. 76 FR 60489 - Lynn E. Stevenson; Notice of Termination of License by Implied Surrender and Soliciting Comments...

    Science.gov (United States)

    2011-09-29

    ... of the Snake River in Gooding County, ID (T. 6 S., R. 13 E., sec. 18, lot 7, Boise Meridian, Idaho... containing a single generating unit with a rated capacity of 70 kW; (5) a tailrace discharging into the Snake... available for inspection and reproduction at the Commission in the Public Reference Room or may be viewed on...

  1. Discretization of space and time: a slight modification to the Newtonian gravitation which implies the existence of black holes

    OpenAIRE

    Roatta , Luca

    2017-01-01

    Assuming that space and time can only have discrete values, it is shown how deformed space and time cause gravitational attraction, whose law in a discrete context is slightly different from the Newtonian, but to it exactly coincident at large distance. This difference is directly connected to the existence of black holes, which result to have the structure of a hollow sphere.

  2. Thermodynamic Description of Synergy in Solvent Extraction: II Thermodynamic Balance of Driving Forces Implied in Synergistic Extraction.

    Science.gov (United States)

    Rey, J; Bley, M; Dufrêche, J-F; Gourdin, S; Pellet-Rostaing, S; Zemb, T; Dourdain, S

    2017-11-21

    In the second part of this study, we analyze the free energy of transfer in the case of synergistic solvent extraction. This free energy of the transfer of an ion in dynamic equilibrium between two coexisting phases is decomposed into four driving forces combining long-range interactions with the classical complexation free energy associated with the nearest neighbors. We demonstrate how the organometallic complexation is counterbalanced by the cost in free energy related to structural change on the colloidal scale in the solvent phase. These molecular forces of synergistic extraction are driven not only by the entropic term associated with the tight packing of electrolytes in the solvent and by the free energy cost of coextracting water toward the hydrophilic core of the reverse aggregates present but also by the entropic costs in the formation of the reverse aggregate and by the interfacial bending energy of the extractant molecules packed around the extracted species. Considering the sum of the terms, we can rationalize the synergy observed, which cannot be explained by classical extraction modeling. We show an industrial synergistic mixture combining an amide and a phosphate complexing site, where the most efficient/selective mixture is observed for a minimal bending energy and maximal complexation energy.

  3. Long-time tails do not necessarily imply self-organized criticality or the breakdown of the standard transport paradigm

    International Nuclear Information System (INIS)

    Krommes, J.A.; Ottaviani, M.

    2000-01-01

    Numerical measurements and analytical studies are performed on a stochastic model with features relevant to plasma confinement. Although the model lacks crucial features of self-organized criticality (SOC) and its transport can be computed by standard techniques, it nevertheless exhibits intermittency and algebraic time correlations. This suggests that SOC need not be the explanation for observed long-time tails in experimental fluctuation data. Arguments based on the renormalized spectral balance equation, and simulation of a standard nonlinear paradigm, predict a range of Hurst exponents in reasonable agreement with the observations without invoking submarginal dynamics

  4. The role of interleukin-18 in glioblastoma pathology implies therapeutic potential of two old drugs-disulfiram and ritonavir.

    Science.gov (United States)

    Kast, Richard E

    2015-04-09

    Based on reporting in the last several years, an impressive but dismal list of cytotoxic chemotherapies that fail to prolong the median overall survival of patients with glioblastoma has prompted the development of treatment protocols designed to interfere with growth-facilitating signaling systems by using non-cytotoxic, non-oncology drugs. Recent recognition of the pro-mobility stimulus, interleukin-18, as a driver of centrifugal glioblastoma cell migration allows potential treatment adjuncts with disulfiram and ritonavir. Disulfiram and ritonavir are well-tolerated, non-cytotoxic, non-oncology chemotherapeutic drugs that are marketed for the treatment of alcoholism and human immunodeficiency virus (HIV) infection, respectively. Both drugs exhibit an interleukin-18-inhibiting function. Given the favorable tolerability profile of disulfiram and ritonavir, the unlikely drug-drug interaction with temozolomide, and the poor prognosis of glioblastoma, trials of addition of disulfiram and ritonavir to current standard initial treatment of glioblastoma would be warranted.

  5. Optimal control of soybean aphid in the presence of natural enemies and the implied value of their ecosystem services.

    Science.gov (United States)

    Zhang, Wei; Swinton, Scott M

    2012-04-15

    By suppressing pest populations, natural enemies provide an important ecosystem service that maintains the stability of agricultural ecosystems systems and potentially mitigates producers' pest control costs. Integrating natural control services into decisions about pesticide-based control has the potential to significantly improve the economic efficiency of pesticide use, with socially desirable outcomes. Two gaps have hindered the incorporation of natural enemies into pest management decision rules: (1) insufficient knowledge of pest and predator population dynamics and (2) lack of a decision framework for the economic tradeoffs among pest control options. Using a new intra-seasonal, dynamic bioeconomic optimization model, this study assesses how predation by natural enemies contributes to profit-maximizing pest management strategies. The model is applied to the management of the invasive soybean aphid, the most significant serious insect threat to soybean production in North America. The resulting lower bound estimate of the value of natural pest control ecosystem services was estimated at $84 million for the states of Illinois, Indiana, Iowa, Michigan and Minnesota in 2005. Copyright © 2011 Elsevier Ltd. All rights reserved.

  6. Uniform spatial distribution of collagen fibril radii within tendon implies local activation of pC-collagen at individual fibrils

    Science.gov (United States)

    Rutenberg, Andrew D.; Brown, Aidan I.; Kreplak, Laurent

    2016-08-01

    Collagen fibril cross-sectional radii show no systematic variation between the interior and the periphery of fibril bundles, indicating an effectively constant rate of collagen incorporation into fibrils throughout the bundle. Such spatially homogeneous incorporation constrains the extracellular diffusion of collagen precursors from sources at the bundle boundary to sinks at the growing fibrils. With a coarse-grained diffusion equation we determine stringent bounds, using parameters extracted from published experimental measurements of tendon development. From the lack of new fibril formation after birth, we further require that the concentration of diffusing precursors stays below the critical concentration for fibril nucleation. We find that the combination of the diffusive bound, which requires larger concentrations to ensure homogeneous fibril radii, and lack of nucleation, which requires lower concentrations, is only marginally consistent with fully processed collagen using conservative bounds. More realistic bounds may leave no consistent concentrations. Therefore, we propose that unprocessed pC-collagen diffuses from the bundle periphery followed by local C-proteinase activity and subsequent collagen incorporation at each fibril. We suggest that C-proteinase is localized within bundles, at fibril surfaces, during radial fibrillar growth. The much greater critical concentration of pC-collagen, as compared to fully processed collagen, then provides broad consistency between homogeneous fibril radii and the lack of fibril nucleation during fibril growth.

  7. Forecasting Daily Variability of the S and P 100 Stock Index using Historical, Realised and Implied Volatility Measurements

    NARCIS (Netherlands)

    Koopman, Siem Jan; Jungbacker, Borus; Hol, Eugenie

    2004-01-01

    The increasing availability of financial market data at intraday frequencies has not only led to the development of improved volatility measurements but has also inspired research into their potential value as an information source for volatility forecasting. In this paper we explore the forecasting

  8. Forecasting daily variability of the S&P 100 stock index using historical, realised and implied volatility measurements

    NARCIS (Netherlands)

    Koopman, S.J.; Jungbacker, B.M.J.P.; Hol, E.

    2005-01-01

    The increasing availability of financial market data at intraday frequencies has not only led to the development of improved volatility measurements but has also inspired research into their potential value as an information source for volatility forecasting. In this paper, we explore the

  9. Extensions of the Survival Advantage in Memory: Examining the Role of Ancestral Context and Implied Social Isolation

    Science.gov (United States)

    Kostic, Bogdan; McFarlan, Chastity C.; Cleary, Anne M.

    2012-01-01

    Recent work (e.g., Nairne & Pandeirada, 2010) has shown that words are remembered better when they have been processed for their survival value in a grasslands context than when processed in other contexts. It has been suggested that this is because human memory systems were shaped by evolution specifically to help humans survive. Thus far,…

  10. Actual versus Implied Physics Students: How Students from Traditional Physics Classrooms Related to an Innovative Approach to Quantum Physics

    Science.gov (United States)

    Bøe, Maria Vetleseter; Henriksen, Ellen Karoline; Angell, Carl

    2018-01-01

    Calls for renewal of physics education include more varied learning activities and increased focus on qualitative understanding and history and philosophy of science (HPS) aspects. We have studied an innovative approach implementing such features in quantum physics in traditional upper secondary physics classrooms in Norway. Data consists of 11…

  11. Resolution among major placental mammal interordinal relationships with genome data imply that speciation influenced their earliest radiations

    Directory of Open Access Journals (Sweden)

    Janke Axel

    2008-05-01

    Full Text Available Abstract Background A number of the deeper divergences in the placental mammal tree are still inconclusively resolved despite extensive phylogenomic analyses. A recent analysis of 200 kbp of protein coding sequences yielded only limited support for the relationships among Laurasiatheria (cow, dog, bat and shrew, probably because the divergences occurred only within a few million years from each other. It is generally expected that increasing the amount of data and improving the taxon sampling enhance the resolution of narrow divergences. Therefore these and other difficult splits were examined by phylogenomic analysis of the hitherto largest sequence alignment. The increasingly complete genome data of placental mammals also allowed developing a novel and stringent data search method. Results The rigorous data handling, recursive BLAST, successfully removed the sequences from gene families, including those from well-known families hemoglobin, olfactory, myosin and HOX genes, thus avoiding alignment of possibly paralogous sequences. The current phylogenomic analysis of 3,012 genes (2,844,615 nucleotides from a total of 22 species yielded statistically significant support for most relationships. While some major clades were confirmed using genomic sequence data, the placement of the treeshrew, bat and the relationship between Boreoeutheria, Xenarthra and Afrotheria remained problematic to resolve despite the size of the alignment. Phylogenomic analysis of divergence times dated the basal placental mammal splits at 95–100 million years ago. Many of the following divergences occurred only a few (2–4 million years later. Relationships with narrow divergence time intervals received unexpectedly limited support even from the phylogenomic analyses. Conclusion The narrow temporal window within which some placental divergences took place suggests that inconsistencies and limited resolution of the mammalian tree may have their natural explanation in speciation processes such as lineage sorting, introgression from species hybridization or hybrid speciation. These processes obscure phylogenetic analysis, making some parts of the tree difficult to resolve even with genome data.

  12. Forecasting Daily Variability of the S&P 100 Stock Index using Historical, Realised and Implied Volatility Measurements

    OpenAIRE

    Koopman, Siem Jan; Jungbacker, Borus; Hol, Eugenie

    2004-01-01

    This discussion paper resulted in an article in the Journal of Empirical Finance (2005). Vol. 12, issue 3, pages 445-475. The increasing availability of financial market data at intraday frequencies has not only led to the development of improved volatility measurements but has also inspired research into their potential value as an information source for volatility forecasting. In this paper we explore the forecasting value of historical volatility (extracted from daily return series), of im...

  13. Effect of thermal implying during ageing process of nanorods growth on the properties of zinc oxide nanorod arrays

    Energy Technology Data Exchange (ETDEWEB)

    Ismail, A. S., E-mail: kyrin-samaxi@yahoo.com; Mamat, M. H., E-mail: mhmamat@salam.uitm.edu.my; Rusop, M., E-mail: rusop@salam.uitm.my [NANO-ElecTronic Centre (NET), Faculty of Electrical Engineering, Universiti Teknologi MARA (UiTM), 40450 Shah Alam, Selangor (Malaysia); NANO-SciTech Centre (NST), Institute of Science (IOS), Universiti Teknologi MARA - UiTM, 40450 Shah Alam, Selangor (Malaysia); Malek, M. F., E-mail: firz-solarzelle@yahoo.com; Abdullah, M. A. R., E-mail: ameerridhwan89@gmail.com; Sin, M. D., E-mail: diyana0366@johor.uitm.edu.my [NANO-ElecTronic Centre (NET), Faculty of Electrical Engineering, Universiti Teknologi MARA (UiTM), 40450 Shah Alam, Selangor (Malaysia)

    2016-07-06

    Undoped and Sn-doped Zinc oxide (ZnO) nanostructures have been fabricated using a simple sol-gel immersion method at 95°C of growth temperature. Thermal sourced by hot plate stirrer was supplied to the solution during ageing process of nanorods growth. The results showed significant decrement in the quality of layer produced after the immersion process where the conductivity and porosity of the samples reduced significantly due to the thermal appliance. The structural properties of the samples have been characterized using field emission scanning electron microscopy (FESEM) electrical properties has been characterized using current voltage (I-V) measurement.

  14. LRIT and AIS: An Analysis of October 2010 Data

    Science.gov (United States)

    2014-10-01

    October 2010 ( Zulu ) 83666 Number of LRIT position reports where the first time stamp has a non-zero value for the seconds 1304 Number of unique IMO...data:  There are 83666 LRIT position reports time stamped within October 2010 ( Zulu ) in the dataset that was used. There are around 2700 unique

  15. Estimation of network path segment delays

    Science.gov (United States)

    Nichols, Kathleen Marie

    2018-05-01

    A method for estimation of a network path segment delay includes determining a scaled time stamp for each packet of a plurality of packets by scaling a time stamp for each respective packet to minimize a difference of at least one of a frequency and a frequency drift between a transport protocol clock of a host and a monitoring point. The time stamp for each packet is provided by the transport protocol clock of the host. A corrected time stamp for each packet is determined by removing from the scaled time stamp for each respective packet, a temporal offset between the transport protocol clock and the monitoring clock by minimizing a temporal delay variation of the plurality of packets traversing a segment between the host and the monitoring point.

  16. Estudo dos componentes físicos implicados no ângulo de aterrissagem no movimento do rodante, executado no aparelho solo da ginástica artística Estudio de las componentes físicas implicadas con el ángulo de aterrizaje en el movimiento de rodamiento, ejecutado en el aparato solo de gimnasia artística Study of the physical components implied with the angle of landing in the rolling movement executed at the floor apparatus in artistic gymnastic

    Directory of Open Access Journals (Sweden)

    Edward Rasquinha

    2006-08-01

    deportiva que intriga mucho a los investigadores de esta área de conocimiento por su complejidad. Este trabajo analiza uno de los movimientos más importantes de esta modalidad, el rodamiento. OBJETIVO: Analizar las componentes físicas implicadas con la ejecución del movimiento de rodamiento en el aparato solo, buscando establecer alguna relación entre éstas y el ángulo de aterrizaje medido al final de este elemento acrobático. MÉTODOS: La muestra fue constituida por siete gimnastas, con edades variando entre 14 y 20 años, con un tiempo de entrenamiento mínimo de cinco años. Esta investigación utilizó herramientas metodológicas fundamentadas en principios de mecánica clásica, técnicas de fotogrametría y de tratamientos estadísticos. RESULTADOS: Entre las grandezas físicas implicadas con la ejecución del rodamiento, el torque externo presentó mayor relevancia para este estudio. Así, tratándose este estudio de una investigación con seres humanos, la variabilidad de los resultados obtenidos es comprensible, además de este factor, la diferencia de nivel técnico entre las gimnastas y las oscilaciones de la técnica empleada por una misma gimnasta, observadas durante las ejecuciones de los tests, fueron responsables por la diversidad de los resultados obtenidos. CONCLUSIONES: Por medio de los resultados obtenidos en el presente estudio fue posible concluir que cuanto menor el ángulo de aterrizaje de rodamiento, mayor será el torque externo. También fue verificado que la aceleración inicial, es decir, el momento de corrida influencia directamente en este ángulo y por consecuencia en la producción del torque externo.INTRODUCTION: Biomechanics is a sub-area of physics responsible for the study of the human movement. The artistic gymnastics is a sport modality that intrigues the researchers, in this context; this work comes to analyze one of the movements most important of this modality, the rolling. SCOPE: To analyze the implied physical components

  17. Greenways Pedestrian & Cyclist Counters

    Data.gov (United States)

    Town of Chapel Hill, North Carolina — Pedestrian and cyclist sensor data time stamped from sensors on the Bolin Creek Trail and Meadowmont Trail in Chapel Hill. Each sensor has four value points that...

  18. 75 FR 38835 - Solicitation of Nominations for the United States Department of Labor's Iqbal Masih Award for the...

    Science.gov (United States)

    2010-07-06

    ... of Labor is the date/time stamp of the ILAB/OCFT on the application wrapper or other documentary... currently valid Office of Management and Budget (OMB) control number. This collection of information is...

  19. Citizen Science in the Ironbound Community

    Data.gov (United States)

    U.S. Environmental Protection Agency — Time stamp data of non-identified locations within the Ironbound community. A normalization data table is provided that defines established regression between...

  20. Timing system observations

    International Nuclear Information System (INIS)

    Winans, J.

    1994-01-01

    The purpose of this document is to augment Synchronized Time Stamp Support authored by Jim Kowalkowski. This document provides additional documentation to clarify and explain software involved in timing operations of the accelerator

  1. Evaluation of dynamic message signs and their potential impact on traffic flow.

    Science.gov (United States)

    2013-04-01

    Maryland State Highway Administration (SHA) has a rich data archive of the messages posted to the : Dynamic Message Signs (DMS) and the time stamps when they were posted and taken down. The archive : also contains traffic information surrounding the ...

  2. Time and Frequency Activities at the Lithuanian National Time Standard Laboratory

    National Research Council Canada - National Science Library

    Miskinis, Rimantas

    2007-01-01

    ...), the Datum 2001 and SyncServer S250 NTP servers are used. Laboratory activities on coordination of the BALTICTIME project Reinforcing e-Government services in Baltic States through legal and accountable Digital Time Stamps...

  3. The initiation of lateral roots in the primary roots of maize (Zea mays L.) implies a reactivation of cell proliferation in a group of founder pericycle cells.

    Science.gov (United States)

    Alarcón, M Victoria; Lloret, Pedro G; Martín-Partido, Gervasio; Salguero, Julio

    2016-03-15

    The initiation of lateral roots (LRs) has generally been viewed as a reactivation of proliferative activity in pericycle cells that are committed to initiate primordia. However, it is also possible that pericycle founder cells that initiate LRs never cease proliferative activity but rather are displaced to the most distal root zones while undertaking successive stages of LR initiation. In this study, we tested these two alternative hypotheses by examining the incorporation of 5-bromo-2'-deoxyuridine (BrdU) into the DNA of meristematic root cells of Zea mays. According to the values for the length of the cell cycle and values for cell displacement along the maize root, our results strongly suggest that pericycle cells that initiate LR primordia ceased proliferative activity upon exiting the meristematic zone. This finding is supported by the existence of a root zone between 4 and 20mm from the root cap junction, in which neither mitotic cells nor labelled nuclei were observed in phloem pericycle cells. Copyright © 2016 Elsevier GmbH. All rights reserved.

  4. Cathelicidin-like helminth defence molecules (HDMs: absence of cytotoxic, anti-microbial and anti-protozoan activities imply a specific adaptation to immune modulation.

    Directory of Open Access Journals (Sweden)

    Karine Thivierge

    Full Text Available Host defence peptides (HDPs are expressed throughout the animal and plant kingdoms. They have multifunctional roles in the defence against infectious agents of mammals, possessing both bactericidal and immune-modulatory activities. We have identified a novel family of molecules secreted by helminth parasites (helminth defence molecules; HDMs that exhibit similar structural and biochemical characteristics to the HDPs. Here, we have analyzed the functional activities of four HDMs derived from Schistosoma mansoni and Fasciola hepatica and compared them to human, mouse, bovine and sheep HDPs. Unlike the mammalian HDPs the helminth-derived HDMs show no antimicrobial activity and are non-cytotoxic to mammalian cells (macrophages and red blood cells. However, both the mammalian- and helminth-derived peptides suppress the activation of macrophages by microbial stimuli and alter the response of B cells to cytokine stimulation. Therefore, we hypothesise that HDMs represent a novel family of HDPs that evolved to regulate the immune responses of their mammalian hosts by retaining potent immune modulatory properties without causing deleterious cytotoxic effects.

  5. New Tropical Peatland Gas and Particulate Emissions Factors Indicate 2015 Indonesian Fires Released Far More Particulate Matter (but Less Methane than Current Inventories Imply

    Directory of Open Access Journals (Sweden)

    Martin J. Wooster

    2018-03-01

    Full Text Available Deforestation and draining of the peatlands in equatorial SE Asia has greatly increased their flammability, and in September–October 2015 a strong El Niño-related drought led to further drying and to widespread burning across parts of Indonesia, primarily on Kalimantan and Sumatra. These fires resulted in some of the worst sustained outdoor air pollution ever recorded, with atmospheric particulate matter (PM concentrations exceeding those considered “extremely hazardous to health” by up to an order of magnitude. Here we report unique in situ air quality data and tropical peatland fire emissions factors (EFs for key carbonaceous trace gases (CO2, CH4 and CO and PM2.5 and black carbon (BC particulates, based on measurements conducted on Kalimantan at the height of the 2015 fires, both at locations of “pure” sub-surface peat burning and spreading vegetation fires atop burning peat. PM2.5 are the most significant smoke constituent in terms of human health impacts, and we find in situ PM2.5 emissions factors for pure peat burning to be 17.8 to 22.3 g·kg−1, and for spreading vegetation fires atop burning peat 44 to 61 g·kg−1, both far higher than past laboratory burning of tropical peat has suggested. The latter are some of the highest PM2.5 emissions factors measured worldwide. Using our peatland CO2, CH4 and CO emissions factors (1779 ± 55 g·kg−1, 238 ± 36 g·kg−1, and 7.8 ± 2.3 g·kg−1 respectively alongside in situ measured peat carbon content (610 ± 47 g-C·kg−1 we provide a new 358 Tg (± 30% fuel consumption estimate for the 2015 Indonesian fires, which is less than that provided by the GFEDv4.1s and GFASv1.2 global fire emissions inventories by 23% and 34% respectively, and which due to our lower EFCH4 produces far less (~3× methane. However, our mean in situ derived EFPM2.5 for these extreme tropical peatland fires (28 ± 6 g·kg−1 is far higher than current emissions inventories assume, resulting in our total PM2.5 emissions estimate (9.1 ± 3.5 Tg being many times higher than GFEDv4.1s, GFASv1.2 and FINNv2, despite our lower fuel consumption. We find that two thirds of the emitted PM2.5 come from Kalimantan, one third from Sumatra, and 95% from burning peatlands. Using new geostationary fire radiative power (FRP data we map the fire emissions’ spatio-temporal variations in far greater detail than ever before (hourly, 0.05°, identifying a tropical peatland fire diurnal cycle twice as wide as in neighboring non-peat areas and peaking much later in the day. Our data show that a combination of greatly elevated PM2.5 emissions factors, large areas of simultaneous, long-duration burning, and very high peat fuel consumption per unit area made these Sept to Oct tropical peatland fires the greatest wildfire source of particulate matter globally in 2015, furthering evidence for a regional atmospheric pollution impact whose particulate matter component in particular led to millions of citizens being exposed to extremely poor levels of air quality for substantial periods.

  6. TU-AB-BRA-04: Quantitative Radiomics: Sensitivity of PET Textural Features to Image Acquisition and Reconstruction Parameters Implies the Need for Standards

    International Nuclear Information System (INIS)

    Nyflot, MJ; Yang, F; Byrd, D; Bowen, SR; Sandison, GA; Kinahan, PE

    2015-01-01

    Purpose: Despite increased use of heterogeneity metrics for PET imaging, standards for metrics such as textural features have yet to be developed. We evaluated the quantitative variability caused by image acquisition and reconstruction parameters on PET textural features. Methods: PET images of the NEMA IQ phantom were simulated with realistic image acquisition noise. 35 features based on intensity histograms (IH), co-occurrence matrices (COM), neighborhood-difference matrices (NDM), and zone-size matrices (ZSM) were evaluated within lesions (13, 17, 22, 28, 33 mm diameter). Variability in metrics across 50 independent images was evaluated as percent difference from mean for three phantom girths (850, 1030, 1200 mm) and two OSEM reconstructions (2 iterations, 28 subsets, 5 mm FWHM filtration vs 6 iterations, 28 subsets, 8.6 mm FWHM filtration). Also, patient sample size to detect a clinical effect of 30% with Bonferroni-corrected α=0.001 and 95% power was estimated. Results: As a class, NDM features demonstrated greatest sensitivity in means (5–50% difference for medium girth and reconstruction comparisons and 10–100% for large girth comparisons). Some IH features (standard deviation, energy, entropy) had variability below 10% for all sensitivity studies, while others (kurtosis, skewness) had variability above 30%. COM and ZSM features had complex sensitivities; correlation, energy, entropy (COM) and zone percentage, short-zone emphasis, zone-size non-uniformity (ZSM) had variability less than 5% while other metrics had differences up to 30%. Trends were similar for sample size estimation; for example, coarseness, contrast, and strength required 12, 38, and 52 patients to detect a 30% effect for the small girth case but 38, 88, and 128 patients in the large girth case. Conclusion: The sensitivity of PET textural features to image acquisition and reconstruction parameters is large and feature-dependent. Standards are needed to ensure that prospective trials which incorporate textural features are properly designed to detect clinical endpoints. Supported by NIH grants R01 CA169072, U01 CA148131, NCI Contract (SAIC-Frederick) 24XS036-004, and a research contract from GE Healthcare

  7. Does Adolescent Risk Taking Imply Weak Executive Function? A Prospective Study of Relations between Working Memory Performance, Impulsivity, and Risk Taking in Early Adolescence

    Science.gov (United States)

    Romer, Daniel; Betancourt, Laura M.; Brodsky, Nancy L.; Giannetta, Joan M.; Yang, Wei; Hurt, Hallam

    2011-01-01

    Studies of brain development suggest that the increase in risk taking observed during adolescence may be due to insufficient prefrontal executive function compared to a more rapidly developing subcortical motivation system. We examined executive function as assessed by working memory ability in a community sample of youth (n = 387, ages 10 to 12 at baseline) in three annual assessments to determine its relation to two forms of impulsivity (sensation seeking and acting without thinking) and a wide range of risk and externalizing behavior. Using structural equation modeling, we tested a model in which differential activation of the dorsal and ventral striatum produces imbalance in the function of these brain regions. For youth high in sensation seeking, both regions were predicted to develop with age. However, for youth high in the tendency to act without thinking, the ventral striatum was expected to dominate. The model predicted that working memory ability would exhibit (1) early weakness in youth high in acting without thinking but (2) growing strength in those high in sensation seeking. In addition, it predicted that (3) acting without thinking would be more strongly related to risk and externalizing behavior than sensation seeking. Finally, it predicted that (4) controlling for acting without thinking, sensation seeking would predict later increases in risky and externalizing behavior. All four of these predictions were confirmed. The results indicate that the rise in sensation seeking that occurs during adolescence is not accompanied by a deficit in executive function and therefore requires different intervention strategies from those for youth whose impulsivity is characterized by early signs of acting without thinking. PMID:21884327

  8. Does Adolescent Risk Taking Imply Weak Executive Function? A Prospective Study of Relations between Working Memory Performance, Impulsivity, and Risk Taking in Early Adolescence

    OpenAIRE

    Romer, Daniel; Betancourt, Laura M.; Brodsky, Nancy L.; Giannetta, Joan M.; Yang, Wei; Hurt, Hallam

    2011-01-01

    Studies of brain development suggest that the increase in risk taking observed during adolescence may be due to insufficient prefrontal executive function compared to a more rapidly developing subcortical motivation system. We examined executive function as assessed by working memory ability in a community sample of youth (n = 387, ages 10 to 12 at baseline) in three annual assessments to determine its relation to two forms of impulsivity (sensation seeking and acting without thinking) and a ...

  9. Characterization and Analysis of Whole Transcriptome of Giant Panda Spleens: Implying Critical Roles of Long Non-Coding RNAs in Immunity.

    Science.gov (United States)

    Peng, Rui; Liu, Yuliang; Cai, Zhigang; Shen, Fujun; Chen, Jiasong; Hou, Rong; Zou, Fangdong

    2018-01-01

    Giant pandas, an endangered species, are a powerful symbol of species conservation. Giant pandas may suffer from a variety of diseases. Owing to their highly specialized diet of bamboo, giant pandas are thought to have a relatively weak ability to resist diseases. The spleen is the largest organ in the lymphatic system. However, there is little known about giant panda spleen at a molecular level. Thus, clarifying the regulatory mechanisms of spleen could help us further understand the immune system of the giant panda as well as its conservation. The two giant panda spleens were from two male individuals, one newborn and one an adult, in a non-pathological condition. The whole transcriptomes of mRNA, lncRNA, miRNA, and circRNA in the two spleens were sequenced using the Illumina HiSeq platform. EBseq and IDEG6 were used to observe the differentially expressed genes (DEGs) between these two spleens. Gene Ontology and KEGG analyses were used to annotate the function of DEGs. Furthermore, networks between non-coding RNAs and protein-coding genes were constructed to investigate the relationship between non-coding RNAs and immune-associated genes. By comparative analysis of the whole transcriptomes of these two spleens, we found that one of the major roles of lncRNAs could be involved in the regulation of immune responses of giant panda spleens. In addition, our results also revealed that microRNAs and circRNAs may have evolved to regulate a large set of biological processes of giant panda spleens, and circRNAs may function as miRNA sponges. To our knowledge, this is the first report of lncRNAs and circRNAs in giant panda, which could be a useful resource for further giant panda research. Our study reveals the potential functional roles of miRNAs, lncRNAs, and circRNAs in giant panda spleen. © 2018 The Author(s). Published by S. Karger AG, Basel.

  10. Receipt or Implied Withdrawal of Tacit in Criminal Procedure as Violation of Circumstances Due to the Principles of Lawsuit and Motivation of Decisions

    Directory of Open Access Journals (Sweden)

    Marcelo Serrano Souza

    2016-10-01

    Full Text Available This article analyzes the implicit or tacit receipt of the complaint in criminal proceedings in the light of constitutional principles of due process and the reasons for decisions. The study shows the need for a rational discourse to legitimate judicial decisions in relation to the claimants. The issue is addressed by the deductive method, through doctrinal and jurisprudential research. The article aims to answer whether and to what extent the implicit or tacit receipt of the complaint involves a violation of due process and the reasons for decisions from the perspective of a coherent legal system.

  11. FLT3 mutations in early T-cell precursor ALL characterize a stem cell like leukemia and imply the clinical use of tyrosine kinase inhibitors.

    Directory of Open Access Journals (Sweden)

    Martin Neumann

    Full Text Available Early T-cell precursor acute lymphoblastic leukemia (ETP-ALL has been identified as high-risk subgroup of acute T-lymphoblastic leukemia (T-ALL with a high rate of FLT3-mutations in adults. To unravel the underlying pathomechanisms and the clinical course we assessed molecular alterations and clinical characteristics in a large cohort of ETP-ALL (n = 68 in comparison to non-ETP T-ALL adult patients. Interestingly, we found a high rate of FLT3-mutations in ETP-ALL samples (n = 24, 35%. Furthermore, FLT3 mutated ETP-ALL was characterized by a specific immunophenotype (CD2+/CD5-/CD13+/CD33-, a distinct gene expression pattern (aberrant expression of IGFBP7, WT1, GATA3 and mutational status (absence of NOTCH1 mutations and a low frequency, 21%, of clonal TCR rearrangements. The observed low GATA3 expression and high WT1 expression in combination with lack of NOTCH1 mutations and a low rate of TCR rearrangements point to a leukemic transformation at the pluripotent prothymocyte stage in FLT3 mutated ETP-ALL. The clinical outcome in ETP-ALL patients was poor, but encouraging in those patients with allogeneic stem cell transplantation (3-year OS: 74%. To further explore the efficacy of targeted therapies, we demonstrate that T-ALL cell lines transfected with FLT3 expression constructs were particularly sensitive to tyrosine kinase inhibitors. In conclusion, FLT3 mutated ETP-ALL defines a molecular distinct stem cell like leukemic subtype. These data warrant clinical studies with the implementation of FLT3 inhibitors in addition to early allogeneic stem cell transplantation for this high risk subgroup.

  12. CO2 loss by permafrost thawing implies additional emissions reductions to limit warming to 1.5 or 2 °C

    Science.gov (United States)

    Burke, Eleanor J.; Chadburn, Sarah E.; Huntingford, Chris; Jones, Chris D.

    2018-02-01

    Large amounts of carbon are stored in the permafrost of the northern high latitude land. As permafrost degrades under a warming climate, some of this carbon will decompose and be released to the atmosphere. This positive climate-carbon feedback will reduce the natural carbon sinks and thus lower anthropogenic CO2 emissions compatible with the goals of the Paris Agreement. Simulations using an ensemble of the JULES-IMOGEN intermediate complexity climate model (including climate response and process uncertainty) and a stabilization target of 2 °C, show that including the permafrost carbon pool in the model increases the land carbon emissions at stabilization by between 0.09 and 0.19 Gt C year-1 (10th to 90th percentile). These emissions are only slightly reduced to between 0.08 and 0.16 Gt C year-1 (10th to 90th percentile) when considering 1.5 °C stabilization targets. This suggests that uncertainties caused by the differences in stabilization target are small compared with those associated with model parameterisation uncertainty. Inertia means that permafrost carbon loss may continue for many years after anthropogenic emissions have stabilized. Simulations suggest that between 225 and 345 Gt C (10th to 90th percentile) are in thawed permafrost and may eventually be released to the atmosphere for stabilization target of 2 °C. This value is 60-100 Gt C less for a 1.5 °C target. The inclusion of permafrost carbon will add to the demands on negative emission technologies which are already present in most low emissions scenarios.

  13. Does the expansion of German high voltage power supply system imply health risks?; Geht vom Ausbau elektrischer Hochspannungsleitungen eine Gefahr fuer die menschliche Gesundheit aus?

    Energy Technology Data Exchange (ETDEWEB)

    Kappos, Andreas D.

    2016-07-01

    The decision of the German parliament to gradually close down nuclear power plants mainly located in the south of Germany and to support wind farms in the North Sea mud flats as the dominant regenerative energy source requires the strengthening and enlargement of the power supply system with the installation of new long distance high voltage power lines. The legally fixed dimension and formality of the actual planning process are discussed as well as the legal regulations for the protection of human health. Guided by the assessment of IARC a ''possible'' carcinogenic effect of low frequency electromagnetic fields on people living in the vicinity of high voltage power lines has to be considered. Therefore from a preventive viewpoint the minimal distance of 400 m between newly planned high voltage power lines and human settlements required by law seem justified.

  14. Location of 3-hydroxyproline residues in collagen types I, II, III, and V/XI implies a role in fibril supramolecular assembly.

    Science.gov (United States)

    Weis, Mary Ann; Hudson, David M; Kim, Lammy; Scott, Melissa; Wu, Jiann-Jiu; Eyre, David R

    2010-01-22

    Collagen triple helices are stabilized by 4-hydroxyproline residues. No function is known for the much less common 3-hydroxyproline (3Hyp), although genetic defects inhibiting its formation cause recessive osteogenesis imperfecta. To help understand the pathogenesis, we used mass spectrometry to identify the sites and local sequence motifs of 3Hyp residues in fibril-forming collagens from normal human and bovine tissues. The results confirm a single, essentially fully occupied 3Hyp site (A1) at Pro(986) in A-clade chains alpha1(I), alpha1(II), and alpha2(V). Two partially modified sites (A2 and A3) were found at Pro(944) in alpha1(II) and alpha2(V) and Pro(707) in alpha2(I) and alpha2(V), which differed from A1 in sequence motif. Significantly, the distance between sites 2 and 3, 237 residues, is close to the collagen D-period (234 residues). A search for additional D-periodic 3Hyp sites revealed a fourth site (A4) at Pro(470) in alpha2(V), 237 residues N-terminal to site 3. In contrast, human and bovine type III collagen contained no 3Hyp at any site, despite a candidate proline residue and recognizable A1 sequence motif. A conserved histidine in mammalian alpha1(III) at A1 may have prevented 3-hydroxylation because this site in chicken type III was fully hydroxylated, and tyrosine replaced histidine. All three B-clade type V/XI collagen chains revealed the same three sites of 3Hyp but at different loci and sequence contexts from those in A-clade collagen chains. Two of these B-clade sites were spaced apart by 231 residues. From these and other observations we propose a fundamental role for 3Hyp residues in the ordered self-assembly of collagen supramolecular structures.

  15. Belize it or not:implied contract terms in Marks and Spencer v BNP Paribas

    OpenAIRE

    McCunn, Joanna

    2016-01-01

    In Marks and Spencer v BNP Paribas, the Supreme Court restated the law on the implication of terms in fact, rejecting the previously authoritative approach taken by Lord Hoffmann in Attorney General of Belize v Belize Telecom Ltd. This article examines two major departures from Belize in Lord Neuberger’s leading judgment: the treatment of implication as a process separate from interpretation, and a return to the ‘traditional tests’ for the implication of terms. It argues that these are retrog...

  16. Genomic and phylogenetic analyses of an adenovirus isolated from a corn snake (Elaphe guttata) imply a common origin with members of the proposed new genus Atadenovirus.

    Science.gov (United States)

    Farkas, Szilvia L; Benko, Mária; Elo, Péter; Ursu, Krisztina; Dán, Adám; Ahne, Winfried; Harrach, Balázs

    2002-10-01

    Approximately 60% of the genome of an adenovirus isolated from a corn snake (Elaphe guttata) was cloned and sequenced. The results of homology searches showed that the genes of the corn snake adenovirus (SnAdV-1) were closest to their counterparts in members of the recently proposed new genus ATADENOVIRUS: In phylogenetic analyses of the complete hexon and protease genes, SnAdV-1 indeed clustered together with the atadenoviruses. The characteristic features in the genome organization of SnAdV-1 included the presence of a gene homologous to that for protein p32K, the lack of structural proteins V and IX and the absence of homologues of the E1A and E3 regions. These characteristics are in accordance with the genus-defining markers of atadenoviruses. Comparison of the cleavage sites of the viral protease in core protein pVII also confirmed SnAdV-1 as a candidate member of the genus ATADENOVIRUS: Thus, the hypothesis on the possible reptilian origin of atadenoviruses (Harrach, Acta Veterinaria Hungarica 48, 484-490, 2000) seems to be supported. However, the base composition of DNA sequence (>18 kb) determined from the SnAdV-1 genome showed an equilibrated GC content of 51%, which is unusual for an atadenovirus.

  17. Persistent use of a shorebird staging site in the Yellow Sea despite severe declines in food resources implies a lack of alternatives

    NARCIS (Netherlands)

    Zhang, Shou-Dong; Ma, Zhijun; Choi, Chi-Yeung; Peng, He-Bo; Bai, Qing-Quan; Liu, Wen-Liang; Tan, Kun; Melville, David S.; He, Peng; Chan, Ying-Chi; Piersma, Theunis; van Gils, Jan A.

    2018-01-01

    Many shorebird populations are in decline along the East Asian-Australasian Flyway. The rapid loss of coastal wetlands in the Yellow Sea, which provide critical stop-over sites during migration, is believed to be the cause of the alarming trends. The Yalu Jiang coastal wetland, a protected area in

  18. Virulence and transmissibility of H1N2 influenza virus in ferrets imply the continuing threat of triple-reassortant swine viruses.

    Science.gov (United States)

    Pascua, Philippe Noriel Q; Song, Min-Suk; Lee, Jun Han; Baek, Yun Hee; Kwon, Hyeok-il; Park, Su-Jin; Choi, Eun Hye; Lim, Gyo-Jin; Lee, Ok-Jun; Kim, Si-Wook; Kim, Chul-Joong; Sung, Moon Hee; Kim, Myung Hee; Yoon, Sun-Woo; Govorkova, Elena A; Webby, Richard J; Webster, Robert G; Choi, Young-Ki

    2012-09-25

    Efficient worldwide swine surveillance for influenza A viruses is urgently needed; the emergence of a novel reassortant pandemic H1N1 (pH1N1) virus in 2009 demonstrated that swine can be the direct source of pandemic influenza and that the pandemic potential of viruses prevalent in swine populations must be monitored. We used the ferret model to assess the pathogenicity and transmissibility of predominant Korean triple-reassortant swine (TRSw) H1N2 and H3N2 influenza viruses genetically related to North American strains. Although most of the TRSw viruses were moderately pathogenic, one [A/Swine/Korea/1204/2009; Sw/1204 (H1N2)] was virulent in ferrets, causing death within 10 d of inoculation, and was efficiently transmitted to naive contact ferrets via respiratory droplets. Although molecular analysis did not reveal known virulence markers, the Sw/1204 virus acquired mutations in hemagglutinin (HA) (Asp-225-Gly) and neuraminidase (NA) (Ser-315-Asn) proteins during the single ferret passage. The contact-Sw/1204 virus became more virulent in mice, replicated efficiently in vitro, extensively infected human lung tissues ex vivo, and maintained its ability to replicate and transmit in swine. Reverse-genetics studies further indicated that the HA(225G) and NA(315N) substitutions contributed substantially in altering virulence and transmissibility. These findings support the continuing threat of some field TRSw viruses to human and animal health, reviving concerns on the capacity of pigs to create future pandemic viruses. Apart from warranting continued and enhanced global surveillance, this study also provides evidence on the emerging roles of HA(225G) and NA(315N) as potential virulence markers in mammals.

  19. Yeast two-hybrid screens imply involvement of Fanconi anemia proteins in transcription regulation, cell signaling, oxidative metabolism, and cellular transport.

    Science.gov (United States)

    Reuter, Tanja Y; Medhurst, Annette L; Waisfisz, Quinten; Zhi, Yu; Herterich, Sabine; Hoehn, Holger; Gross, Hans J; Joenje, Hans; Hoatlin, Maureen E; Mathew, Christopher G; Huber, Pia A J

    2003-10-01

    Mutations in one of at least eight different genes cause bone marrow failure, chromosome instability, and predisposition to cancer associated with the rare genetic syndrome Fanconi anemia (FA). The cloning of seven genes has provided the tools to study the molecular pathway disrupted in Fanconi anemia patients. The structure of the genes and their gene products provided few clues to their functional role. We report here the use of 3 FA proteins, FANCA, FANCC, and FANCG, as "baits" in the hunt for interactors to obtain clues for FA protein functions. Using five different human cDNA libraries we screened 36.5x10(6) clones with the technique of the yeast two-hybrid system. We identified 69 proteins which have not previously been linked to the FA pathway as direct interactors of FANCA, FANCC, or FANCG. Most of these proteins are associated with four functional classes including transcription regulation (21 proteins), signaling (13 proteins), oxidative metabolism (10 proteins), and intracellular transport (11 proteins). Interaction with 6 proteins, DAXX, Ran, IkappaBgamma, USP14, and the previously reported SNX5 and FAZF, was additionally confirmed by coimmunoprecipitation and/or colocalization studies. Taken together, our data strongly support the hypothesis that FA proteins are functionally involved in several complex cellular pathways including transcription regulation, cell signaling, oxidative metabolism, and cellular transport.

  20. Biochemistry of storage lesions of red cell and platelet concentrates: A continuous fight implying oxidative/nitrosative/phosphorylative stress and signaling.

    Science.gov (United States)

    Rinalducci, Sara; Zolla, Lello

    2015-06-01

    The mechanisms responsible for the reduced lifespan of transfused red blood cells (RBCs) and platelets (PLTs) are still under investigation, however one explanation refers to the detrimental biochemical changes occurring during ex vivo storage of these blood products. A myriad of historical and more recent studies has contributed to advance our understanding of storage lesion. Without any doubts, proteomics had great impact on transfusion medicine by profiling the storage-dependent changes in the total detectable protein pool of both RBCs and PLTs. This review article focuses on the role of oxidative/nitrosative stress in developing RBC and PLT storage lesions, with a special glance at its biochemistry and cross-talk with phosphorylative signal transduction. In this sense, we enlighten the potential contribution of new branches of proteomics in identifying novel points of intervention for the improvement of blood product quality. Copyright © 2015 Elsevier Ltd. All rights reserved.

  1. How does the Earth system generate and maintain thermodynamic disequilibrium and what does it imply for the future of the planet?

    Science.gov (United States)

    Kleidon, Axel

    2012-01-01

    The Earth's chemical composition far from chemical equilibrium is unique in our Solar System, and this uniqueness has been attributed to the presence of widespread life on the planet. Here, I show how this notion can be quantified using non-equilibrium thermodynamics. Generating and maintaining disequilibrium in a thermodynamic variable requires the extraction of power from another thermodynamic gradient, and the second law of thermodynamics imposes fundamental limits on how much power can be extracted. With this approach and associated limits, I show that the ability of abiotic processes to generate geochemical free energy that can be used to transform the surface–atmosphere environment is strongly limited to less than 1 TW. Photosynthetic life generates more than 200 TW by performing photochemistry, thereby substantiating the notion that a geochemical composition far from equilibrium can be a sign for strong biotic activity. Present-day free energy consumption by human activity in the form of industrial activity and human appropriated net primary productivity is of the order of 50 TW and therefore constitutes a considerable term in the free energy budget of the planet. When aiming to predict the future of the planet, we first note that since global changes are closely related to this consumption of free energy, and the demands for free energy by human activity are anticipated to increase substantially in the future, the central question in the context of predicting future global change is then how human free energy demands can increase sustainably without negatively impacting the ability of the Earth system to generate free energy. This question could be evaluated with climate models, and the potential deficiencies in these models to adequately represent the thermodynamics of the Earth system are discussed. Then, I illustrate the implications of this thermodynamic perspective by discussing the forms of renewable energy and planetary engineering that would enhance the overall free energy generation and, thereby ‘empower’ the future of the planet. PMID:22291221

  2. Molecular assessment, characterization, and differentiation of theca stem cells imply the presence of mesenchymal and pluripotent stem cells in sheep ovarian theca layer.

    Science.gov (United States)

    Adib, Samane; Valojerdi, Mojtaba Rezazadeh

    2017-10-01

    The ability of ovarian theca stem cells to differentiate into oocyte and theca cells may lead to a major advancement in reproductive biology and infertility treatments. However, there is little information about function, growth and differentiation potential of these immature cells. In this study adult sheep theca stem cells (TSCs) characteristics, and differentiation potential into osteocyte-like cells (OSLCs), adipocyte-like cells (ALCs), theca progenitor-like cells (TPCs), and oocyte-like cells (OLCs) were investigated. TSCs were isolated, cultured, and compared with mesenchymal stem cells (MSCs), fibroblast cells (FCs), and pluripotent embryonic ovarian cells (EO). Adherent TSCs were morphologically similar to FCs. Cell cycle analysis showed high proliferation capacity of TSCs. TSCs were positive for the mesenchymal cells surface markers, and also expressed POU5F1. Differentiation potential of TSCs into OSLCs and ALCs were confirmed by alizarin red and oil red staining respectively. OSTEOCALCIN and COL1 were expressed in OSLCs. ALCs were positive for PPARα and LPL. TPCs expressed theca specific genes (GLI2, GLI3, PTCH1, CYP17A1, 3β-HSD and LHR) and secreted testosterone, dehydroepiandrostenedione (DHEA), androstenedione, progesterone and estradiol. Lipid droplets in these steroid cells were viewed by oil red staining. OLCs expressed oocyte-specific marker genes including, ZP3, ZP2, GDF9, SYCP3, PRDM1, STELLA, FRAGILIS, DAZL, as well as POU5F1, and showed separated sphere structure. Our results indicated that TSCs derived from ovarian follicles contain MSCs and pluripotent stem cells (PSCs) that can be differentiated into lineages of mesenchymal origin and are capable of differentiation into TPCs and OLCs under in vitro conditions. Copyright © 2017 Elsevier Ltd. All rights reserved.

  3. Comorbidity of obsessive-compulsive disorder with obsessive-compulsive personality disorder: Does it imply a specific subtype of obsessive-compulsive disorder?

    Science.gov (United States)

    Garyfallos, George; Katsigiannopoulos, Konstantinos; Adamopoulou, Aravela; Papazisis, Georgios; Karastergiou, Anastasia; Bozikas, Vasilios P

    2010-05-15

    The present study examined whether the comorbidity of obsessive-compulsive personality disorder (OCPD) and obsessive-compulsive disorder (OCD) constitute a specific subtype of OCD. The study sample consisted of 146 consecutive outpatients with a DSM-IV diagnosis of OCD. Diagnoses were established using MINI, IPDE, YBOCS and YBOCS-SC. OCD patients with comorbid OCPD were compared with OCD patients without OCPD on various sociodemographic and clinical variables. Almost one third of the OCD subjects met criteria for comorbid OCPD. OCD+OCPD patients had a significantly earlier age at onset of initial OC symptoms, earlier age at onset of OCD and more obsessions and compulsions than pure obsessions compared to the patients with OCDOCPD. OCD+OCPD patients also had a higher rate of comorbidity with avoidant personality disorder and showed more impairment in global functioning. There were not differences between the two sub-groups on severity of OCD symptoms and also on type of OCD onset. Our results indicate that the comorbidity of OCD with OCPD is associated with a number of specific clinical characteristics of OCD. These findings in conjunction with of current clinical, family and genetic studies provide some initial evidence that OCD comorbid with OCPD constitute a specific subtype of OCD. Copyright 2010 Elsevier Ireland Ltd. All rights reserved.

  4. Legal size limit implies strong fisheries selection on sexually selected traits in a temperate wrasse providing male-only parental care

    Directory of Open Access Journals (Sweden)

    Kim Aleksander Tallaksen Halvorsen

    2015-12-01

    Full Text Available Corkwing wrasse (Symphodus melops is a temperate wrasse displaying both sex and male dimorphism and is targeted in a size selective commercial fishery which has increased dramatically since 2008. Wrasses are supplied alive to salmon farms as cleaner fish to combat infestations of Salmon lice. In previous studies, growth and maturation has been found to differ among male morphs and sexes and these groups might therefore be targeted unevenly by the size selective fishery. In the present study, we address this by comparing size regulations and fishing practice with data on sex specific growth and maturation from Western and Southern Norway, two regions varying in density and life histories. Two years of field data on density and length measures was used together with a subsample of otoliths to determine sex specific growth patterns. In the region with high density, nesting males were found to grow faster and mature later than sneaker males and females. Here, most nesting males will reach the minimum size as juveniles, one and two years before females and sneakers respectively. In contrast, sexual dimorphism was much less pronounced in the low density region, and relaxed male-male competition over nesting sites seems a likely explanation for this pattern. Intensive harvesting with selective removal of the larger nesting males could potentially lead to short term effect such as sperm limitation and reduced offspring survival and thus affect the productivity of juveniles. In addition, the current fishing regime may select for reduced growth rates and earlier maturation and oppose sexual selection.

  5. Differential diagnosis of "Religious or Spiritual Problem" - possibilities and limitations implied by the V-code 62.89 in DSM-5.

    Science.gov (United States)

    Prusak, Jacek

    2016-01-01

    Introduction : Work over preparation of DSM-5 has been a stimulus for research and reflection over the impact of religious/spiritual factors on phenomenology, differential diagnosis, course, outcome and prognosis of mental disorders. The aim of this paper is to present the attitude of DSM towards religion and spirituality in the clinical context. Even though DSM is not in use in Poland, in contrast to ICD, it gives a different, not only psychopathological, look at religious or spiritual problems. The paper is based on in-depth analysis of V-code 62.89 ("Religious or spiritual problem") from historical, theoretical and clinical perspective. The introduction of non-reductive approach to religious and spiritual problems to DSM can be considered as a manifestation of the development of this psychiatric classification with regard to the differential diagnosis between religion and spirituality and psychopathology. By placing religion and spirituality mainly in the category of culture, the authors of DSM-5 have established their solution to the age-old debate concerning the significance of religion/spirituality in clinical practice. Even though, DSM-5 offers an expanded understanding of culture and its impact on diagnosis, the V-code 62.89 needs to be improved taking into account some limitations of DSM classification. The development of DSM, from its fourth edition, brought a change into the approach towards religion and spirituality in the context of clinical diagnosis. Introducing V-code 62.89 has increased the possibility of differential diagnosis between religion/spirituality and health/psychopathology. The emphasis on manifestation of cultural diversity has enabled non-reductive and non-pathologising insight into the problems of religious and spirituality. On the other hand, medicalisation and psychiatrisation of various existential problems, which can be seen in subsequent editions of the DSM, encourages pathologising approach towards religious or spiritual problems. Clinical look at religion and spirituality should therefore go beyond the limitations of DSM.

  6. Systemic Responses of Multidrug-Resistant Pseudomonas aeruginosa and Acinetobacter baumannii Following Exposure to the Antimicrobial Peptide Cathelicidin-BF Imply Multiple Intracellular Targets

    Directory of Open Access Journals (Sweden)

    Cunbao Liu

    2017-11-01

    Full Text Available Cathelicidin-BF, derived from the banded krait (Bungarus fasciatus, is a typically cationic, amphiphilic and α-helical antimicrobial peptide (AMP with 30 amino acids that exerts powerful effects on multidrug-resistant (MDR clinical isolates, including Pseudomonas aeruginosa, Acinetobacter baumannii, and Klebsiella pneumoniae, but whether it targets plasma membranes or intracellular targets to kill bacteria is still controversial. In the present study, we demonstrated that the disruption of bacterial membranes with high concentrations of cathelicidin-BF was the cause of bacterial death, as with conventional antibiotics at high concentrations. At lower concentrations, cathelicidin-BF did not cause bacterial plasma membrane disruption, but it was able to cross the membrane and aggregate at the nucleoid regions. Functional proteins of the transcription processes of P. aeruginosa and A. baumannii were affected by sublethal doses of cathelicidin-BF, as demonstrated by comparative proteomics using isobaric tags for relative and absolute quantification and subsequent gene ontology (GO analysis. Analysis using the Kyoto Encyclopedia of Genes and Genomes showed that cathelicidin-BF mainly interferes with metabolic pathways related to amino acid synthesis, metabolism of cofactors and vitamins, metabolism of purine and energy supply, and other processes. Although specific targets of cathelicidin-BF must still be validated, our study offers strong evidence that cathelicidin-BF may act upon intracellular targets to kill superbugs, which may be helpful for further efforts to discover novel antibiotics to fight against them.

  7. Sexual behavior and awareness of Chinese university students in transition with implied risk of sexually transmitted diseases and HIV infection: A cross-sectional study

    Directory of Open Access Journals (Sweden)

    Ma Qiaoqin

    2006-09-01

    Full Text Available Abstract Background The vulnerability of young people to HIV and the recent emergence of the HIV epidemic in China have made it urgent to assess and update the HIV/STD risk profile of Chinese young people. Methods A self-administered questionnaire survey with cross-sectional design was conducted among 22,493 undergraduate students in two universities in Ningbo, China. Bivariate trend analysis and multiple logistic regression analysis were used to compare sexual behaviors and awareness between grades. Results Of respondents, 17.6% of males and 8.6% of females reported being sexually active. Condom was reported never/rarely used by 35% of sexually active students in both genders in the previous year. Pregnancy and induced abortion had each been experienced by about 10% of sexually active female students and the female partners of male students, and about 1.5% of sexually active students of both genders reported being diagnosed with an STD. Multivariate analysis revealed that students in lower grades, compared to those in higher grades, were more likely to have become sexually active before university, to have become aware of sex before high school, and to have been exposed to pornographic media before the age of 17 years, and for sexually active respondents of both genders, to have engaged in sex without using a condom. Conclusion Sexual behaviors of Chinese university students are poorly protected and sexual behaviors and awareness may have been undergoing rapid change, becoming active earlier and more risky. If this trend continues, vulnerable sexual network will grow among them that allow more expansion of sexually transmitted diseases and HIV.

  8. TU-AB-BRA-04: Quantitative Radiomics: Sensitivity of PET Textural Features to Image Acquisition and Reconstruction Parameters Implies the Need for Standards

    Energy Technology Data Exchange (ETDEWEB)

    Nyflot, MJ; Yang, F; Byrd, D; Bowen, SR; Sandison, GA; Kinahan, PE [University of Washington, Seattle, WA (United States)

    2015-06-15

    Purpose: Despite increased use of heterogeneity metrics for PET imaging, standards for metrics such as textural features have yet to be developed. We evaluated the quantitative variability caused by image acquisition and reconstruction parameters on PET textural features. Methods: PET images of the NEMA IQ phantom were simulated with realistic image acquisition noise. 35 features based on intensity histograms (IH), co-occurrence matrices (COM), neighborhood-difference matrices (NDM), and zone-size matrices (ZSM) were evaluated within lesions (13, 17, 22, 28, 33 mm diameter). Variability in metrics across 50 independent images was evaluated as percent difference from mean for three phantom girths (850, 1030, 1200 mm) and two OSEM reconstructions (2 iterations, 28 subsets, 5 mm FWHM filtration vs 6 iterations, 28 subsets, 8.6 mm FWHM filtration). Also, patient sample size to detect a clinical effect of 30% with Bonferroni-corrected α=0.001 and 95% power was estimated. Results: As a class, NDM features demonstrated greatest sensitivity in means (5–50% difference for medium girth and reconstruction comparisons and 10–100% for large girth comparisons). Some IH features (standard deviation, energy, entropy) had variability below 10% for all sensitivity studies, while others (kurtosis, skewness) had variability above 30%. COM and ZSM features had complex sensitivities; correlation, energy, entropy (COM) and zone percentage, short-zone emphasis, zone-size non-uniformity (ZSM) had variability less than 5% while other metrics had differences up to 30%. Trends were similar for sample size estimation; for example, coarseness, contrast, and strength required 12, 38, and 52 patients to detect a 30% effect for the small girth case but 38, 88, and 128 patients in the large girth case. Conclusion: The sensitivity of PET textural features to image acquisition and reconstruction parameters is large and feature-dependent. Standards are needed to ensure that prospective trials which incorporate textural features are properly designed to detect clinical endpoints. Supported by NIH grants R01 CA169072, U01 CA148131, NCI Contract (SAIC-Frederick) 24XS036-004, and a research contract from GE Healthcare.

  9. Coherent Behavior and the Bound State of Water and K(+) Imply Another Model of Bioenergetics: Negative Entropy Instead of High-energy Bonds.

    Science.gov (United States)

    Jaeken, Laurent; Vasilievich Matveev, Vladimir

    2012-01-01

    Observations of coherent cellular behavior cannot be integrated into widely accepted membrane (pump) theory (MT) and its steady state energetics because of the thermal noise of assumed ordinary cell water and freely soluble cytoplasmic K(+). However, Ling disproved MT and proposed an alternative based on coherence, showing that rest (R) and action (A) are two different phases of protoplasm with different energy levels. The R-state is a coherent metastable low-entropy state as water and K(+) are bound to unfolded proteins. The A-state is the higher-entropy state because water and K(+) are free. The R-to-A phase transition is regarded as a mechanism to release energy for biological work, replacing the classical concept of high-energy bonds. Subsequent inactivation during the endergonic A-to-R phase transition needs an input of metabolic energy to restore the low entropy R-state. Matveev's native aggregation hypothesis allows to integrate the energetic details of globular proteins into this view.

  10. Unexpected ancestry of Populus seedlings from a hybrid zone implies a large role for postzygotic selection in the maintenance of species.

    Science.gov (United States)

    Lindtke, Dorothea; Gompert, Zachariah; Lexer, Christian; Buerkle, C Alex

    2014-09-01

    In the context of potential interspecific gene flow, the integrity of species will be maintained by reproductive barriers that reduce genetic exchange, including traits associated with prezygotic isolation or poor performance of hybrids. Hybrid zones can be used to study the importance of different reproductive barriers, particularly when both parental species and hybrids occur in close spatial proximity. We investigated the importance of barriers to gene flow that act early vs. late in the life cycle of European Populus by quantifying the prevalence of homospecific and hybrid matings within a mosaic hybrid zone. We obtained genotypic data for 11 976 loci from progeny and their maternal parents and constructed a Bayesian model to estimate individual admixture proportions and hybrid classes for sampled trees and for the unsampled pollen parent. Matings that included one or two hybrid parents were common, resulting in admixture proportions of progeny that spanned the whole range of potential ancestries between the two parental species. This result contrasts strongly with the distribution of admixture proportions in adult trees, where intermediate hybrids and each of the parental species are separated into three discrete ancestry clusters. The existence of the full range of hybrids in seedlings is consistent with weak reproductive isolation early in the life cycle of Populus. Instead, a considerable amount of selection must take place between the seedling stage and maturity to remove many hybrid seedlings. Our results highlight that high hybridization rates and appreciable hybrid fitness do not necessarily conflict with the maintenance of species integrity. © 2014 John Wiley & Sons Ltd.

  11. Does the Presence of Primary Circulating Prostate Cells Imply the Presence of Agressive Prostate Cancer with Early Biochemical Failure: a Comparison with the Walz Nomogram.

    Science.gov (United States)

    Murray, Nigel P; Reyes, Eduardo; Orellana, Nelson; Fuentealba, Cynthia; Orellana, Sebastian; Jacob, Omar

    2016-01-01

    To determine the utility of primary circulating prostate cells (CPC) for predicting early biochemical failure after radical prostatectomy for prostate cancer and compare the results with the Walz nomogram. A single centre prospective study of men with prostate cancer treated with radical prostatectomy was conducted between 2004 and 2014. Clinicalpathological details were registered, along with total serum PSA presurgery, Gleason score, extracapsular extension, positive surgical margins, infiltration of lymph nodes, seminal vesicles and pathological stage. Primary circulating prostate cells were obtained using differential gel centrifugation and detected using standard immunocytochemistry with antiPSA. Biochemical failure was defined as a PSA >0.2ng/ml, predictive values were calculated using the Walz nomagram and CPC detection. A total of 285 men participated, of whom 103/285 (36.1%) suffered biochemcial failure; 32/103 (31.1%) within two years of radical prostatectomy. Men with higher Gleason scores, higher pathological stage, infiltration of the surgical margin or prostate capsule and infiltration of seminal vesicles were more likely to undergo biochemical failure. There was a significant increase in the frequency of biochemical failure with increasing number of CPCs detected (p<0.0004 Chi squared for trend) and increasing percent prediction for the Walz nomogram (p<0.0001 Chi squared for trends). The positive predictive value of primary CPC detection, even using a cutoff point of ≥ 4 cells/sample was very low. The detection of primary CPCs in men as a prognostic factor pretreatment fails to identify those at high risk of biochemical failure within two years of curative therapy. This is in keeping with their biological significance, that the majority of them will be eliminated by the primary therapy and thus have no influence on the subsequent clinical history of the patient.

  12. Yeast two-hybrid screens imply involvement of Fanconi anemia proteins in transcription regulation, cell signaling, oxidative metabolism, and cellular transport.

    NARCIS (Netherlands)

    Reuter, TY; Medhurst, A.L. dr.; Waisfisz, Q.; Zhi, Y.; Herterich, S.; Hoehn, H.; Gross, H.J.; Joenje, H.; Hoatlin, M.E.; Mathew, C.G.; Huber, PA

    2003-01-01

    Mutations in one of at least eight different genes cause bone marrow failure, chromosome instability, and predisposition to cancer associated with the rare genetic syndrome Fanconi anemia (FA). The cloning of seven genes has provided the tools to study the molecular pathway disrupted in Fanconi

  13. Receptor complementation and mutagenesis reveal SR-BI as an essential HCV entry factor and functionally imply its intra- and extra-cellular domains.

    Directory of Open Access Journals (Sweden)

    Marlène Dreux

    2009-02-01

    Full Text Available HCV entry into cells is a multi-step and slow process. It is believed that the initial capture of HCV particles by glycosaminoglycans and/or lipoprotein receptors is followed by coordinated interactions with the scavenger receptor class B type I (SR-BI, a major receptor of high-density lipoprotein (HDL, the CD81 tetraspanin, and the tight junction protein Claudin-1, ultimately leading to uptake and cellular penetration of HCV via low-pH endosomes. Several reports have indicated that HDL promotes HCV entry through interaction with SR-BI. This pathway remains largely elusive, although it was shown that HDL neither associates with HCV particles nor modulates HCV binding to SR-BI. In contrast to CD81 and Claudin-1, the importance of SR-BI has only been addressed indirectly because of lack of cells in which functional complementation assays with mutant receptors could be performed. Here we identified for the first time two cell types that supported HCVpp and HCVcc entry upon ectopic SR-BI expression. Remarkably, the undetectable expression of SR-BI in rat hepatoma cells allowed unambiguous investigation of human SR-BI functions during HCV entry. By expressing different SR-BI mutants in either cell line, our results revealed features of SR-BI intracellular domains that influence HCV infectivity without affecting receptor binding and stimulation of HCV entry induced by HDL/SR-BI interaction. Conversely, we identified positions of SR-BI ectodomain that, by altering HCV binding, inhibit entry. Finally, we characterized alternative ectodomain determinants that, by reducing SR-BI cholesterol uptake and efflux functions, abolish HDL-mediated infection-enhancement. Altogether, we demonstrate that SR-BI is an essential HCV entry factor. Moreover, our results highlight specific SR-BI determinants required during HCV entry and physiological lipid transfer functions hijacked by HCV to favor infection.

  14. Heavy-Quark Symmetry Implies Stable Heavy Tetraquark Mesons Q_{i}Q_{j}q[over ¯]_{k}q[over ¯]_{l}.

    Science.gov (United States)

    Eichten, Estia J; Quigg, Chris

    2017-11-17

    For very heavy quarks Q, relations derived from heavy-quark symmetry predict the existence of novel narrow doubly heavy tetraquark states of the form Q_{i}Q_{j}q[over ¯]_{k}q[over ¯]_{l} (subscripts label flavors), where q designates a light quark. By evaluating finite-mass corrections, we predict that double-beauty states composed of bbu[over ¯]d[over ¯], bbu[over ¯]s[over ¯], and bbd[over ¯]s[over ¯] will be stable against strong decays, whereas the double-charm states ccq[over ¯]_{k}q[over ¯]_{l}, mixed beauty+charm states bcq[over ¯]_{k}q[over ¯]_{l}, and heavier bbq[over ¯]_{k}q[over ¯]_{l} states will dissociate into pairs of heavy-light mesons. Observation of a new double-beauty state through its weak decays would establish the existence of tetraquarks and illuminate the role of heavy color-antitriplet diquarks as hadron constituents.

  15. Strong minor groove base conservation in sequence logos implies DNA distortion or base flipping during replication and transcription initiation | Center for Cancer Research

    Science.gov (United States)

    Dubbed "Tom's T" by Dhruba Chattoraj, the unusually conserved thymine at position +7 in bacteriophage P1 plasmid RepA DNA binding sites rises above repressor and acceptor sequence logos. The T appears to represent base flipping prior to helix opening in this DNA replication initation protein.

  16. Time-series variations of the short-lived Ra in coastal waters: implying input of SGD to the coastal zone of Da-Chia River, Taichung, Taiwan

    Science.gov (United States)

    Hsu, Feng-Hsin; Su, Chih-Chieh; Lin, In-Tain; Huh, Chih-An

    2015-04-01

    Submarine groundwater discharge (SGD) has been recognized as an important pathway for materials exchanging between land and sea. Input of SGD carries the associated nutrients, trace metals, and inorganic carbon that may makes great impacts on ecosystem in the coastal zone. Due to the variability of SGD magnitude, it is difficult to estimate the flux of those associated materials around the world. Even in the same area, SGD magnitude also varies in response to tide fluctuation and seasonal change on hydraulic gradient. Thus, long-term investigation is in need. In Taiwan, the SGD study is rare and the intrusion of seawater in the coastal aquifer is emphasized in previous studies. According to the information from Hydrogeological Data Bank (Central Geological Survey, MOEA), some areas still show potentiality of SGD. Here, we report the preliminary investigation result of SGD at Gaomei Wildlife Conservation Area which located at the south of the Da-Chia River mouth. This study area is characterized by a great tidal rang and a shallow aquifer with high groundwater recharge rate. Time-series measurement of the short-lived Ra in surface water was done in both dry and wet seasons at a tidal flat site and shows different trends of excess Ra-224 between dry and wet seasons. High excess Ra-224 activities (>20 dpm/100L) occurred at high tide in dry season but at low tide in wet season. The plot of salinity versus excess Ra-224, showing non-conservative curve, suggests that high excess Ra-224 activities derive from desorption in dry season but from SGD input in wet season.

  17. Imprints from genetic drift and mutation imply relative divergence times across marine transition zones in a Pan European small pelagic fish (Sprattus sprattus)

    DEFF Research Database (Denmark)

    Limborg, Morten; Hanel, R.; Debes, P.

    2012-01-01

    .) by combining inference from both mtDNA and microsatellite genetic markers throughout the species’ distribution. We compared effects from genetic drift and mutation for both genetic markers in shaping genetic differentiation across four transition zones. Microsatellite markers revealed significant isolation...... by distance and a complex population structure across the species0 distribution (overall yST¼0.038, Po0.01). Across transition zones markers indicated larger effects of genetic drift over mutations in the northern distribution of sprat contrasting a stronger relative impact of mutation in the species...

  18. The training of neonatologists and the paradigms implied in their relationship with the parents of babies in the Neonatal Intensive Care Unit

    Directory of Open Access Journals (Sweden)

    Ethel Cukierkorn Battikha

    2014-03-01

    Full Text Available Objective: To analyze and to interpret the psychological repercussions generated by the presence of parents in the Neonatal Intensive Care Unit for residents in Neonatology. Methods: Study based on the psychoanalytic theory, involving a methodological interface with qualitative surveys in Health Sciences. Twenty resident physicians in Neonatology, from five public institutions of São Paulo state, responded to a single semi-structured interview. Based on several readings of the material, achieving the core of emergent meanings that would be significant to the object of the survey, six categories were elected for analysis and interpretation: parents' staying at the Neonatal Intensive Care Unit and its effects on the neonatologists' professional practice; communication of the diagnosis and what parents should know; impasses between parents and doctors when the diagnosis is being communicated; doctor's identification with parents; communication of the child's death and their participation in the interview. Results: The interpretation of the categories provided an understanding of the psychic mechanisms mobilized in doctors in their relationships with the children's parents, showing that the residents experience anguish and suffering when they provide medical care and during their training process, and also that they lack psychological support to handle these feelings. Conclusions: There is a need of intervention in neonatologists training and education, which may favor the elaboration of daily experiences in the Unit, providing a less anguishing and defensive way out for young doctors, especially in their relationship with patients and parents.

  19. Brief report on a systematic review of youth violence prevention through media campaigns: Does the limited yield of strong evidence imply methodological challenges or absence of effect?

    Science.gov (United States)

    Cassidy, Tali; Bowman, Brett; McGrath, Chloe; Matzopoulos, Richard

    2016-10-01

    We present a brief report on a systematic review which identified, assessed and synthesized the existing evidence of the effectiveness of media campaigns in reducing youth violence. Search strategies made use of terms for youth, violence and a range of terms relating to the intervention. An array of academic databases and websites were searched. Although media campaigns to reduce violence are widespread, only six studies met the inclusion criteria. There is little strong evidence to support a direct link between media campaigns and a reduction in youth violence. Several studies measure proxies for violence such as empathy or opinions related to violence, but the link between these measures and violence perpetration is unclear. Nonetheless, some evidence suggests that a targeted and context-specific campaign, especially when combined with other measures, can reduce violence. However, such campaigns are less cost-effective to replicate over large populations than generalised campaigns. It is unclear whether the paucity of evidence represents a null effect or methodological challenges with evaluating media campaigns. Future studies need to be carefully planned to accommodate for methodological difficulties as well as to identify the specific elements of campaigns that work, especially in lower and middle income countries. Copyright © 2016 The Foundation for Professionals in Services for Adolescents. Published by Elsevier Ltd. All rights reserved.

  20. THE VARIABILITY OF HCN IN TITAN’S UPPER ATMOSPHERE AS IMPLIED BY THE CASSINI ION-NEUTRAL MASS SPECTROMETER MEASUREMENTS

    Energy Technology Data Exchange (ETDEWEB)

    Cui, J.; Cao, Y.-T. [National Astronomical Observatories, Chinese Academy of Sciences, Beijing 100012 (China); Lavvas, P. P. [Groupe de Spectroscopie Moleculaire et Atmospherique, Universite de Reims, Champagne-Ardenne, CNRS UMR F-7331 (France); Koskinen, T. T. [Lunar and Planetary Laboratory, University of Arizona, Tucson, AZ 85721 (United States)

    2016-07-20

    HCN is an important constituent in Titan’s upper atmosphere, serving as the main coolant in the local energy budget. In this study, we derive the HCN abundance at the altitude range of 960–1400 km, combining the Ion-Neutral Mass Spectrometer data acquired during a large number of Cassini flybys with Titan. Typically, the HCN abundance declines modestly with increasing altitude and flattens to a near constant level above 1200 km. The data reveal a tendency for dayside depletion of HCN, which is clearly visible below 1000 km but weakens with increasing altitude. Despite the absence of convincing anti-correlation between HCN volume mixing ratio and neutral temperature, we argue that the variability in HCN abundance makes an important contribution to the large temperature variability observed in Titan’s upper atmosphere.

  1. Divergent Response Profile in Activated Cord Blood T cells from First-born Child Implies Birth-order-associated in Utero Immune Programming

    DEFF Research Database (Denmark)

    Kragh, Marie; Larsen, Jeppe Madura; Thysen, Anna Hammerich

    2016-01-01

    Background: First-born children are at higher risk for development of a range of immune-mediated diseases. The underlying mechanism of ‘birth-order-effects’ on disease risk is largely unknown, but in utero programming of the child's immune system may play a role. Objective: We studied the associa...... programing may contribute to later development of immune-mediated diseases by increasing overall immune reactivity in first-born children as compared to younger siblings.......Background: First-born children are at higher risk for development of a range of immune-mediated diseases. The underlying mechanism of ‘birth-order-effects’ on disease risk is largely unknown, but in utero programming of the child's immune system may play a role. Objective: We studied...

  2. Introduzione: le politiche keynesiane non riguardano solo, né sempre, la spesa pubblica.(Introduction: Keynesian Policies Do not only, nor always, Imply Public Expenditure

    Directory of Open Access Journals (Sweden)

    Carlo D'Ippoliti

    2012-04-01

    Full Text Available The brief note introduces the articles collected in the present issue of the journal. It places the various contributions in perspective, critically summarizing the major economic developments since the publication of the last issue.JEL: E11, G01, B50, H12  

  3. Switzerland: What does the EURATOM Directive imply for a non-EU-Member State?; Schweiz: was bedeutet die EURATOM-Richtlinie fuer ein Nicht-EG-Land?

    Energy Technology Data Exchange (ETDEWEB)

    Jeschki, W. [Hauptabt. fuer die Sicherheit der Kernanlagen (HSK), Villigen (Switzerland). Abt. Strahlenschutz und Notfallplanung; Stoll, E. [Hauptabt. fuer die Sicherheit der Kernanlagen (HSK), Villigen (Switzerland). Sektion Radiologischer Arbeitsschutz

    1997-12-31

    Member States of the EU are obliged to transform the Directive and its legal and administrative provisions into national laws by 13 March 2000. Switzerland is not a Member State, and hence is not obliged to provide for harmonisation of its legal regime with the European provisions, but there are reasons advocating consideration of the European Basic Standards and appropriate necessary action at the national level. The contribution here explains relevant aspects and the impacts on the radiation protection regime in Switzerland. (orig./CB) [Deutsch] Die Mitgliedstaaten der EU sind aufgefordert, bis zum 13. Maerz 2000 die erforderlichen Rechts- und Verwaltungsvorschriften zu schaffen, um der Richtlinie 96/29 EURATOM nachzukommen. Die Schweiz gehoert derzeit nicht zur EG. Sie muss daher ihre Strahlenschutz-Gesetzgebung nicht nach der EG-Richtlinie ausrichten. Dennoch gibt es Gruende, dass sich die Schweiz mit der Richtlinie auseinandersetzt. Die Bedeutung fuer den Strahlenschutz in der Schweiz wird im Folgenden erlaeutert. (orig.)

  4. Self-similar rupture implied by scaling properties of volcanic earthquakes occurring during the 2004-2008 eruption of Mount St. Helens, Washington

    Science.gov (United States)

    Harrington, Rebecca M.; Kwiatek, Grzegorz; Moran, Seth C.

    2015-01-01

    We analyze a group of 6073 low-frequency earthquakes recorded during a week-long temporary deployment of broadband seismometers at distances of less than 3 km from the crater at Mount St. Helens in September of 2006. We estimate the seismic moment (M0) and spectral corner frequency (f0) using a spectral ratio approach for events with a high signal-to-noise (SNR) ratio that have a cross-correlation coefficient of 0.8 or greater with at least five other events. A cluster analysis of cross-correlation values indicates that the group of 421 events meeting the SNR and cross-correlation criteria forms eight event families that exhibit largely self-similar scaling. We estimate the M0 and f0 values of the 421 events and calculate their static stress drop and scaled energy (ER/M0) values. The estimated values suggest self-similar scaling within families, as well as between five of eight families (i.e.,  and  constant). We speculate that differences in scaled energy values for the two families with variable scaling may result from a lack of resolution in the velocity model. The observation of self-similar scaling is the first of its kind for such a large group of low-frequency volcanic tectonic events occurring during a single active dome extrusion eruption.

  5. Characterization and Analysis of Whole Transcriptome of Giant Panda Spleens: Implying Critical Roles of Long Non-Coding RNAs in Immunity

    Directory of Open Access Journals (Sweden)

    Rui Peng

    2018-04-01

    Full Text Available Background/Aims: Giant pandas, an endangered species, are a powerful symbol of species conservation. Giant pandas may suffer from a variety of diseases. Owing to their highly specialized diet of bamboo, giant pandas are thought to have a relatively weak ability to resist diseases. The spleen is the largest organ in the lymphatic system. However, there is little known about giant panda spleen at a molecular level. Thus, clarifying the regulatory mechanisms of spleen could help us further understand the immune system of the giant panda as well as its conservation. Methods: The two giant panda spleens were from two male individuals, one newborn and one an adult, in a non-pathological condition. The whole transcriptomes of mRNA, lncRNA, miRNA, and circRNA in the two spleens were sequenced using the Illumina HiSeq platform. EBseq and IDEG6 were used to observe the differentially expressed genes (DEGs between these two spleens. Gene Ontology and KEGG analyses were used to annotate the function of DEGs. Furthermore, networks between non-coding RNAs and protein-coding genes were constructed to investigate the relationship between non-coding RNAs and immune-associated genes. Results: By comparative analysis of the whole transcriptomes of these two spleens, we found that one of the major roles of lncRNAs could be involved in the regulation of immune responses of giant panda spleens. In addition, our results also revealed that microRNAs and circRNAs may have evolved to regulate a large set of biological processes of giant panda spleens, and circRNAs may function as miRNA sponges. Conclusion: To our knowledge, this is the first report of lncRNAs and circRNAs in giant panda, which could be a useful resource for further giant panda research. Our study reveals the potential functional roles of miRNAs, lncRNAs, and circRNAs in giant panda spleen.

  6. Retina as Reciprocal Spatial Fourier Transform Space Implies ``Wave-transformation'' Functions, String Theory, the Inappropriate Uncertainty Principle, and Predicts ``Quarked'' Protons.

    Science.gov (United States)

    Mc Leod, Roger David; Mc Leod, David M.

    2007-10-01

    Vision, via transform space: ``Nature behaves in a reciprocal way;' also, Rect x pressure-input sense-reports as Sinc p, indicating brain interprets reciprocal ``p'' space as object space. Use Mott's and Sneddon's Wave Mechanics and Its Applications. Wave transformation functions are strings of positron, electron, proton, and neutron; uncertainty is a semantic artifact. Neutrino-string de Broglie-Schr"odinger wave-function models for electron, positron, suggest three-quark models for protons, neutrons. Variably vibrating neutrino-quills of this model, with appropriate mass-energy, can be a vertical proton string, quills leftward; thread string circumferentially, forming three interlinked circles with ``overpasses''. Diameters are 2:1:2, center circle has quills radially outward; call it a down quark, charge --1/3, charge 2/3 for outward quills, the up quarks of outer circles. String overlap summations are nodes; nodes also far left and right. Strong nuclear forces may be --px. ``Dislodging" positron with neutrino switches quark-circle configuration to 1:2:1, `downers' outside. Unstable neutron charge is 0. Atoms build. With scale factors, retinal/vision's, and quantum mechanics,' spatial Fourier transforms/inverses are equivalent.

  7. The Drivers of the CH4 Seasonal Cycle in the Arctic and What Long-Term Observations of CH4 Imply About Trends in Arctic CH4 Fluxes

    Science.gov (United States)

    Sweeney, C.; Karion, A.; Bruhwiler, L.; Miller, J. B.; Wofsy, S. C.; Miller, C. E.; Chang, R. Y.; Dlugokencky, E. J.; Daube, B.; Pittman, J. V.; Dinardo, S. J.

    2012-12-01

    The large seasonal change in the atmospheric column for CH4 in the Arctic is driven by two dominant processes: transport of CH4 from low latitudes and surface emissions throughout the Arctic region. The NOAA ESRL Carbon Cycle Group Aircraft Program along with the NASA funded Carbon in Arctic Reservoirs Vulnerability Experiment (CARVE) have initiated an effort to better understand the factors controlling the seasonal changes in the mole fraction of CH4 in the Arctic with a multi-scale aircraft observing network in Alaska. The backbone of this network is multi-species flask sampling from 500 to 8000 masl that has been conducted every two weeks for the last 10 years over Poker Flat, AK. In addition regular profiles at the interior Alaska site at Poker Flat, NOAA has teamed up with the United States Coast Guard to make profiling flights with continuous observations of CO2, CO, CH4 and Ozone between Kodiak and Barrow every 2 weeks. More recently, CARVE has significantly added to this observational network with targeted flights focused on exploring the variability of CO2, CH4 and CO in the boundary layer both in the interior and the North Slope regions of Alaska. Taken together with the profiling of HIAPER Pole-to-Pole Observations (HIPPO), ground sites at Barrow and a new CARVE interior Alaska surface site just north of Fairbanks, AK, we now have the ability to investigate the full evolution of the seasonal cycle in the Arctic using both the multi-scale sampling offered by the different aircraft platforms as well as the multi-species sampling offered by in-situ and flask sampling. The flasks also provide a valuable tie-point between different platforms so that spatial and temporal gradients can be properly interpreted. In the context of the seasonal cycle observed by the aircraft platforms we will look at long term ground observations over the last 20 years to assess changes in Arctic CH4 emissions which have occurred as a result of 0.6C/decade changes in mean surface temperatures.

  8. How does the Earth system generate and maintain thermodynamic disequilibrium and what does it imply for the future of the planet?

    Science.gov (United States)

    Kleidon, Axel

    2012-03-13

    The Earth's chemical composition far from chemical equilibrium is unique in our Solar System, and this uniqueness has been attributed to the presence of widespread life on the planet. Here, I show how this notion can be quantified using non-equilibrium thermodynamics. Generating and maintaining disequilibrium in a thermodynamic variable requires the extraction of power from another thermodynamic gradient, and the second law of thermodynamics imposes fundamental limits on how much power can be extracted. With this approach and associated limits, I show that the ability of abiotic processes to generate geochemical free energy that can be used to transform the surface-atmosphere environment is strongly limited to less than 1 TW. Photosynthetic life generates more than 200 TW by performing photochemistry, thereby substantiating the notion that a geochemical composition far from equilibrium can be a sign for strong biotic activity. Present-day free energy consumption by human activity in the form of industrial activity and human appropriated net primary productivity is of the order of 50 TW and therefore constitutes a considerable term in the free energy budget of the planet. When aiming to predict the future of the planet, we first note that since global changes are closely related to this consumption of free energy, and the demands for free energy by human activity are anticipated to increase substantially in the future, the central question in the context of predicting future global change is then how human free energy demands can increase sustainably without negatively impacting the ability of the Earth system to generate free energy. This question could be evaluated with climate models, and the potential deficiencies in these models to adequately represent the thermodynamics of the Earth system are discussed. Then, I illustrate the implications of this thermodynamic perspective by discussing the forms of renewable energy and planetary engineering that would enhance the overall free energy generation and, thereby 'empower' the future of the planet.

  9. Involving stakeholders in policy research should not imply that they control the problem definition: lessons from a case study on new analgesics

    NARCIS (Netherlands)

    Moret-Hartman, M.; van der Wilt, G.J.; Grin, J.

    2009-01-01

    The Dutch Health Care Insurance Board (HCIB) commissions research to guide their policy recommendations. However, the studies conducted do not always yield relevant information. This may result from differences in problem definitions held by the HCIB and target populations. To compensate these

  10. Does the validity of the first law of thermodynamics imply that the generalized second law of thermodynamics of the universe is bounded by the event horizon?

    International Nuclear Information System (INIS)

    Mazumder, Nairwita; Chakraborty, Subenoy

    2009-01-01

    In this work we examine the validity of the generalized second law of thermodynamics of the universe with the event horizon as the boundary assuming the first law of thermodynamics. We consider a homogeneous and isotropic model of the universe, filled with perfect fluid having an arbitrary equation of state. We study the validity of the generalized second law both in Einstein and Einstein-Gauss-Bonnet (EGB) gravity.

  11. Comprehensive survey of carapacial ridge-specific genes in turtle implies co-option of some regulatory genes in carapace evolution.

    Science.gov (United States)

    Kuraku, Shigehiro; Usuda, Ryo; Kuratani, Shigeru

    2005-01-01

    The turtle shell is an evolutionary novelty in which the developmental pattern of the ribs is radically modified. In contrast to those of other amniotes, turtle ribs grow laterally into the dorsal dermis to form a carapace. The lateral margin of carapacial primordium is called the carapacial ridge (CR), and is thought to play an essential role in carapace patterning. To reveal the developmental mechanisms underlying this structure, we systematically screened for genes expressed specifically in the CR of the Chinese soft-shelled turtle, Pelodiscus sinensis, using microbead-based differential cDNA analysis and real-time reverse transcription-polymerase chain reaction. We identified orthologs of Sp5, cellular retinoic acid-binding protein-I (CRABP-I), adenomatous polyposis coli down-regulated 1 (APCDD1), and lymphoid enhancer-binding factor-1 (LEF-1). Although these genes are conserved throughout the major vertebrate lineages, comparison of their expression patterns with those in chicken and mouse indicated that these genes have acquired de novo expression in the CR in the turtle lineage. In association with the expression of LEF-1, the nuclear localization of beta-catenin protein was detected in the CR ectoderm, suggesting that the canonical Wnt signaling triggers carapace development. These findings indicate that the acquisition of the turtle shell did not involve the creation of novel genes, but was based on the co-option of pre-existing genes.

  12. Microstructural and compositional features of the fibrous and hyaline cartilage on the medial tibial plateau imply a unique role for the hopping locomotion of kangaroo.

    Directory of Open Access Journals (Sweden)

    Bo He

    Full Text Available Hopping provides efficient and energy saving locomotion for kangaroos, but it results in great forces in the knee joints. A previous study has suggested that a unique fibrous cartilage in the central region of the tibial cartilage could serve to decrease the peak stresses generated within kangaroo tibiofemoral joints. However, the influences of the microstructure, composition and mechanical properties of the central fibrous and peripheral hyaline cartilage on the function of the knee joints are still to be defined. The present study showed that the fibrous cartilage was thicker and had a lower chondrocyte density than the hyaline cartilage. Despite having a higher PG content in the middle and deep zones, the fibrous cartilage had an inferior compressive strength compared to the peripheral hyaline cartilage. The fibrous cartilage had a complex three dimensional collagen meshwork with collagen bundles parallel to the surface in the superficial zone, and with collagen bundles both parallel and perpendicular to the surface in the middle and deep zones. The collagen in the hyaline cartilage displayed a typical Benninghoff structure, with collagen fibres parallel to the surface in the superficial zone and collagen fibres perpendicular to the surface in the deep zone. Elastin fibres were found throughout the entire tissue depth of the fibrous cartilage and displayed a similar alignment to the adjacent collagen bundles. In comparison, the elastin fibres in the hyaline cartilage were confined within the superficial zone. This study examined for the first time the fibrillary structure, PG content and compressive properties of the central fibrous cartilage pad and peripheral hyaline cartilage within the kangaroo medial tibial plateau. It provided insights into the microstructure and composition of the fibrous and peripheral hyaline cartilage in relation to the unique mechanical properties of the tissues to provide for the normal activities of kangaroos.

  13. Microstructural and compositional features of the fibrous and hyaline cartilage on the medial tibial plateau imply a unique role for the hopping locomotion of kangaroo.

    Science.gov (United States)

    He, Bo; Wu, Jian Ping; Xu, Jiake; Day, Robert E; Kirk, Thomas Brett

    2013-01-01

    Hopping provides efficient and energy saving locomotion for kangaroos, but it results in great forces in the knee joints. A previous study has suggested that a unique fibrous cartilage in the central region of the tibial cartilage could serve to decrease the peak stresses generated within kangaroo tibiofemoral joints. However, the influences of the microstructure, composition and mechanical properties of the central fibrous and peripheral hyaline cartilage on the function of the knee joints are still to be defined. The present study showed that the fibrous cartilage was thicker and had a lower chondrocyte density than the hyaline cartilage. Despite having a higher PG content in the middle and deep zones, the fibrous cartilage had an inferior compressive strength compared to the peripheral hyaline cartilage. The fibrous cartilage had a complex three dimensional collagen meshwork with collagen bundles parallel to the surface in the superficial zone, and with collagen bundles both parallel and perpendicular to the surface in the middle and deep zones. The collagen in the hyaline cartilage displayed a typical Benninghoff structure, with collagen fibres parallel to the surface in the superficial zone and collagen fibres perpendicular to the surface in the deep zone. Elastin fibres were found throughout the entire tissue depth of the fibrous cartilage and displayed a similar alignment to the adjacent collagen bundles. In comparison, the elastin fibres in the hyaline cartilage were confined within the superficial zone. This study examined for the first time the fibrillary structure, PG content and compressive properties of the central fibrous cartilage pad and peripheral hyaline cartilage within the kangaroo medial tibial plateau. It provided insights into the microstructure and composition of the fibrous and peripheral hyaline cartilage in relation to the unique mechanical properties of the tissues to provide for the normal activities of kangaroos.

  14. Toxicological effects, mechanisms, and implied toxicity thresholds in the roots of Vicia faba L. seedlings grown in copper-contaminated soil.

    Science.gov (United States)

    Xu, Xianghua; Huang, Zhicheng; Wang, Chengrun; Zhong, Li; Tian, Yuan; Li, Dongdong; Zhang, Gaojian; Shi, Jian

    2015-09-01

    Copper (Cu) contamination has become a global concern because of industrial, agricultural, and other anthropogenic activities. In the present experiments, the toxicological effects, mechanisms, and potential toxicity thresholds were investigated in the roots of Vicia faba L. seedlings that were cultivated in Cu-amended soils (0, 6.25, 12.5, 25, 50, 100, 200, 400, and 600 mg kg(-1)) for 20 days, based on an analysis of the soil physicochemical properties, native Cu, available Cu, and root-enriched Cu contents. The superoxide dismutase (SOD), ascorbate peroxidase (APX), and guaiacol peroxidase (POD) isozymes and activities, as well as glutathione (GSH) and heat shock protein 70 (HSP70), changed like biphasic dose-response curves, cooperating to control the redox homeostasis. The APX and POD enzymes exhibited enhanced activities and became H2O2 scavengers primarily when the catalase (CAT) activities tended to decrease. Endoprotease (EP) isozymes and activities might be enhanced to degrade carbonylated proteins and alleviate metabolic disturbance in the roots. Additionally, HSP70 may not be suitable as a biomarker for relatively higher soil Cu concentrations and relatively longer exposure times for the roots. As a result, the isozymes and activities of SOD, CAT, and EP, as well as GSH, can be adopted as the most sensitive biomarkers. The toxicity threshold is estimated as 0.76-1.21 mg kg(-1) of available Cu in the soils or 25.04-36.65 μg Cu g(-1) dry weights (DW) in the roots.

  15. The ALTA global positioning satellite based timing system

    CERN Document Server

    Brouwer, W; Caron, B; Hewlett, J C; Holm, L; Hamilton, A H; McDonald, W J; Pinfold, J L; Schaapman, J R; Soluk, R A; Wampler, L J

    2002-01-01

    The Alberta Large-area Time-coincidence Array (ALTA) experiment uses a number of scintillation detector systems to form a sparse very large area cosmic air-shower detection array. An important scientific goal of the ALTA collaboration is to search for coincidences in the ALTA array due to large area cosmic ray phenomena. A local cosmic ray event, determined by a coincidence of the triplet of cosmic ray detectors forming a local detector system, is time stamped with a temporal coordinate obtained from a GPS receiver. The readout of the data, the local coincidence and the GPS time stamp are all performed in the local readout crate. This time stamp, along with the local shower direction is used to search for coincidences within the large area array. Using two GPS receivers and duplicate sets of ALTA electronics the timing resolution of the GPS time difference between sites was estimated to be 16 ns.

  16. Anytime Coevolution of Form and Function

    National Research Council Canada - National Science Library

    Bugajska, Magdalena D; Schultz, Alan C

    2003-01-01

    ...) for autonomous vehicles. This study focuses on coevolution of the characteristics such as beam width and range of individual sensors in the sensor suite, and the reactive strategies for collision-free navigation...

  17. A New Key-lock Method for User Authentication and Access Control

    Institute of Scientific and Technical Information of China (English)

    JI Dongyao; ZHANG Futai; WANG Yumin

    2001-01-01

    We propose a new key-lock methodfor user authentication and access control based onChinese remainder theorem, the concepts of the ac-cess control matrix, key-lock-pair, time stamp, and the NS public key protocol. Our method is dynamicand needs a minimum amount of computation in thesense that it only updates at most one key/lock foreach access request. We also demonstrate how an au-thentication protocol can be integrated into the ac-cess control method. By applying a time stamp, themethod can not only withstand replay attack, butalso strengthen the authenticating mechanism, whichcould not be achieved simultaneously in previous key-lock methods.

  18. Advances in knowledge discovery in databases

    CERN Document Server

    Adhikari, Animesh

    2015-01-01

    This book presents recent advances in Knowledge discovery in databases (KDD) with a focus on the areas of market basket database, time-stamped databases and multiple related databases. Various interesting and intelligent algorithms are reported on data mining tasks. A large number of association measures are presented, which play significant roles in decision support applications. This book presents, discusses and contrasts new developments in mining time-stamped data, time-based data analyses, the identification of temporal patterns, the mining of multiple related databases, as well as local patterns analysis.  

  19. Pulses processor modeling of the AR-PET tomograph

    International Nuclear Information System (INIS)

    Martinez Garbino, Lucio J.; Venialgo, E.; Estryk, Daniel S.; Verrastro, Claudio A.

    2009-01-01

    The detection of two gamma photons in time coincidence is the main process in Positron Emission Tomography. The front end processor estimate the energy and the time stamp of each incident gamma photon, the accuracy of such estimation improves the quality of contrast and resolution of final images. In this work a modeling tool of the full detection chain is described. Starting from stochastic generation of light photons, followed by photoelectrons time transit spread inside the photomultiplier, preamplifier response and digitalisation process were modeling and finally, several algorithms of Energy and Time Stamp estimation were evaluated and compared. (author)

  20. A comparative analysis of the categorization of multidimensional stimuli: I. Unidimensional classification does not necessarily imply analytic processing; evidence from pigeons (Columba livia), squirrels (Sciurus carolinensis), and humans (Homo sapiens).

    Science.gov (United States)

    Wills, A J; Lea, Stephen E G; Leaver, Lisa A; Osthaus, Britta; Ryan, Catriona M E; Suret, Mark B; Bryant, Catherine M L; Chapman, Sue J A; Millar, Louise

    2009-11-01

    Pigeons (Columba livia), gray squirrels (Sciurus carolinensis), and undergraduates (Homo sapiens) learned discrimination tasks involving multiple mutually redundant dimensions. First, pigeons and undergraduates learned conditional discriminations between stimuli composed of three spatially separated dimensions, after first learning to discriminate the individual elements of the stimuli. When subsequently tested with stimuli in which one of the dimensions took an anomalous value, the majority of both species categorized test stimuli by their overall similarity to training stimuli. However some individuals of both species categorized them according to a single dimension. In a second set of experiments, squirrels, pigeons, and undergraduates learned go/no-go discriminations using multiple simultaneous presentations of stimuli composed of three spatially integrated, highly salient dimensions. The tendency to categorize test stimuli including anomalous dimension values unidimensionally was higher than in the first set of experiments and did not differ significantly between species. The authors conclude that unidimensional categorization of multidimensional stimuli is not diagnostic for analytic cognitive processing, and that any differences between human's and pigeons' behavior in such tasks are not due to special features of avian visual cognition.

  1. Administrative instruction relative to the national doctrine of use of rescue and treatments means face to a terrorist action implying radioactive matters n. 800/S.G.D.N./P.S.E./P.P.S. of the 23 april 2003

    International Nuclear Information System (INIS)

    2003-01-01

    This administrative instruction gives the situations where it applies, the principal public services that could get involved. The specific management of alert is detailed by importance level, then come the actions of first aids, the different zones of actions (from the contaminated area to the help area), the protection equipment is specified and the management of damaged people in each area. (N.C.)

  2. Negative Correlation between Circulating CD4+FOXP3+CD127− Regulatory T Cells and Subsequent Antibody Responses to Infant Measles Vaccine but Not Diphtheria–Tetanus–Pertussis Vaccine Implies a Regulatory Role

    Directory of Open Access Journals (Sweden)

    Jorjoh Ndure

    2017-08-01

    Full Text Available Regulatory T cells (Tregs play a key homeostatic role by suppressing immune responses. They have been targeted in mouse and human cancer studies to improve vaccine immunogenicity and tumor clearance. A number of commercially available drugs and experimental vaccine adjuvants have been shown to target Tregs. Infants have high numbers of Tregs and often have poor responses to vaccination, yet the role Tregs play in controlling vaccine immunogenicity has not been explored in this age group. Herein, we explore the role of CD4+FOXP3+CD127− Tregs in controlling immunity in infant males and females to vaccination with diphtheria–tetanus–whole cell pertussis (DTP and/or measles vaccine (MV. We find correlative evidence that circulating Tregs at the time of vaccination suppress antibody responses to MV but not DTP; and Tregs 4 weeks after DTP vaccination may suppress vaccine-specific cellular immunity. This opens the exciting possibility that Tregs may provide a future target for improved vaccine responses in early life, including reducing the number of doses of vaccine required. Such an approach would need to be safe and the benefits outweigh the risks, thus further research in this area is required.

  3. A complete study on the ethiology of malign renal lithiasis based on the determination of other hormones and functional and metabolic parameters implied in these diases. Part of a coordinated programme on in vitro assay techniques

    International Nuclear Information System (INIS)

    Tiberiu, P.

    1979-10-01

    Plasma parathyroid hormone (PTH) and plasma calcitonin (CT) were measured by radioimmunoassay with commercial radioimmunoassay kits and corresponding biochemical and functional studies were carried out in 55 patients with unilateral or bilateral malignant lithiasis and in a group of 10 control subjects. Plasma PTH levels were found to be normal in 5 of the patients and slightly or markedly elevated in 50, whilst plasma CT levels were found to be normal in 52 and slightly elevated in 3. In a further analysis of the data, plasma PTH levels were found to be slightly elevated in 42 out of the 45 patients suffering from renal failure and markedly elevated in 3. The latter were suspected of primary hyperparathyroidism, but in none was any adenoma discovered, either scintigraphically or by other means. It is concluded that secondary reactive hyperparathyroidism may appear in malignant renal lithiasis, but that primary hyperparathyroidism is unlikely to be implicated in the recurrent nature of the disease, which is more likely to result from residual calculi. The significance of these findings in relation to the management of the disease is discussed

  4. Periodic p-adic Gibbs Measures of q-State Potts Model on Cayley Trees I: The Chaos Implies the Vastness of the Set of p-Adic Gibbs Measures

    Science.gov (United States)

    Ahmad, Mohd Ali Khameini; Liao, Lingmin; Saburov, Mansoor

    2018-06-01

    We study the set of p-adic Gibbs measures of the q-state Potts model on the Cayley tree of order three. We prove the vastness of the set of the periodic p-adic Gibbs measures for such model by showing the chaotic behavior of the corresponding Potts-Bethe mapping over Q_p for the prime numbers p≡1 (mod 3). In fact, for 0< |θ -1|_p< |q|_p^2 < 1 where θ =\\exp _p(J) and J is a coupling constant, there exists a subsystem that is isometrically conjugate to the full shift on three symbols. Meanwhile, for 0< |q|_p^2 ≤ |θ -1|_p< |q|_p < 1, there exists a subsystem that is isometrically conjugate to a subshift of finite type on r symbols where r ≥ 4. However, these subshifts on r symbols are all topologically conjugate to the full shift on three symbols. The p-adic Gibbs measures of the same model for the prime numbers p=2,3 and the corresponding Potts-Bethe mapping are also discussed. On the other hand, for 0< |θ -1|_p< |q|_p < 1, we remark that the Potts-Bethe mapping is not chaotic when p=3 and p≡ 2 (mod 3) and we could not conclude the vastness of the set of the periodic p-adic Gibbs measures. In a forthcoming paper with the same title, we will treat the case 0< |q|_p ≤ |θ -1|_p < 1 for all prime numbers p.

  5. cGMP may have trophic effects on beta cell function comparable to those of cAMP, implying a role for high-dose biotin in prevention/treatment of diabetes.

    Science.gov (United States)

    McCarty, Mark F

    2006-01-01

    Incretin hormones have trophic effects on beta cell function that can aid prevention and treatment of diabetes. cAMP is the primary mediator of these effects, and has been shown to potentiate glucose-stimulated insulin secretion, promote proper beta cells differentiation by increasing expression of the crucial transcription factor PDX-1, and prevent beta cell apoptosis. cGMP's role in beta cell function has received far less scrutiny, but there is emerging evidence that it may have a trophic impact on beta cell function analogous to that of cAMP. An increase in plasma glucose boosts beta cell production of cGMP, which acts as a feed-forward mediator to enhance glucose-stimulated insulin secretion. cGMP also has an anti-apoptotic effect in beta cells, and there is now indirect evidence that it promotes expression of PDX-1. Supraphysiological concentrations of biotin can directly activate guanylate cyclase, and there is limited evidence that high intakes of this vitamin can be therapeutically beneficial in diabetics and in rodent models of diabetes. Beneficial effects of cGMP on muscle insulin sensitivity and on control of hepatic glucose output may contribute to biotin's utility in diabetes. The fact that nitric oxide/cGMP exert a range of favorable effects on vascular health should further encourage exploration of biotin's preventive and therapeutic potential. If an appropriate high-dose biotin regimen could achieve a modest systemic increase in guanylate cyclase activity, without entailing unacceptable side effects or risks, such a regimen might have considerable potential for promoting vascular health and preventing or managing diabetes.

  6. Air emission in France. Metropolitan area substances implied in the increasing greenhouse effect; Emissions dans l'air en France. Metropole substances impliquees dans le phenomene d'accroissement de l'effet de serre

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2002-04-01

    Substances and index currently in survey are: Greenhouse effect: CO{sub 2}, CH{sub 4}, N{sub 2}O, HFCs (total and speciation for 8 compounds), PFCs (total and speciation for 5 compounds), SF{sub 6}, global warming potential index based on one hundred years time (GWP). Density ratios relating to population, area, gross product, primary energy consumption, etc. Emissions are presented by the mean of charts for each substance and the main source categories with a five years step until 1990 then yearly beyond. Dates corresponding to the maximum and minimum values are also included. Results are provisional for 2001. (author)

  7. Carrier frequency of a nonsense mutation in the adenosine deaminase (ADA) gene implies a high incidence of ADA-deficient severe combined immunodeficiency (SCID) in Somalia and a single, common haplotype indicates common ancestry

    DEFF Research Database (Denmark)

    Sanchez Sanchez, Juan Jose; Monaghan, Gemma; Børsting, Claus

    2007-01-01

    Inherited adenosine deaminase (ADA) deficiency is a rare metabolic disorder that causes immunodeficiency, varying from severe combined immunodeficiency (SCID) in the majority of cases to a less severe form in a small minority of patients. Five patients of Somali origin from four unrelated families......, with severe ADA-SCID, were registered in the Greater London area. Patients and their parents were investigated for the nonsense mutation Q3X (ADA c7C>T), two missense mutations K80R (ADA c239A>G) and R142Q (ADA c425G>A), and a TAAA repeat located at the 3' end of an Alu element (AluVpA) positioned 1.1 kb...... upstream of the ADA transcription start site. All patients were homozygous for the haplotype ADA-7T/ADA-239G/ADA-425G/AluVpA7. Among 207 Somali immigrants to Denmark, the frequency of ADA c7C>T and the maximum likelihood estimate of the frequency of the haplotype ADA-7T/ADA-239G/ADA-425G/AluVpA7 were both...

  8. Air emissions in France. Metropolitan area substances implied in acidification, eutrophication and photochemistry; Emissions dans l'air en France. Metropole substances impliquees dans les phenomenes d'acidification, d'eutrophisation et de photochimie

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2002-04-01

    Acidification, eutrophication and photochemistry: SO{sub 2}, NO{sub x}, NH{sub 3}, NMVOCs (total and speciation relating to more than 200 different compounds), CO, acid equivalent index (Aeq) and photochemical ozone creation potential (POCP) are presented. Density ratios relating to population, area, gross product, primary energy consumption, etc. Emissions are presented by the mean of charts for each substance and the main source categories with a five years step until 1990 then yearly beyond. Dates corresponding to the maximum and minimum values are also included. (author)

  9. 2004 Puget Sound LiDAR Consortium (PSLC) Topographic LiDAR: Portland, Oregon

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The all returns ASCII files contain the X,Y,Z values of all the LiDAR returns collected during the survey mission. In addition each return also has a time stamp,...

  10. Synchronous Parallel System for Emulation and Discrete Event Simulation

    Science.gov (United States)

    Steinman, Jeffrey S. (Inventor)

    2001-01-01

    A synchronous parallel system for emulation and discrete event simulation having parallel nodes responds to received messages at each node by generating event objects having individual time stamps, stores only the changes to the state variables of the simulation object attributable to the event object and produces corresponding messages. The system refrains from transmitting the messages and changing the state variables while it determines whether the changes are superseded, and then stores the unchanged state variables in the event object for later restoral to the simulation object if called for. This determination preferably includes sensing the time stamp of each new event object and determining which new event object has the earliest time stamp as the local event horizon, determining the earliest local event horizon of the nodes as the global event horizon, and ignoring events whose time stamps are less than the global event horizon. Host processing between the system and external terminals enables such a terminal to query, monitor, command or participate with a simulation object during the simulation process.

  11. Time-of-flight measurements of heavy ions using Si PIN diodes

    Energy Technology Data Exchange (ETDEWEB)

    Strekalovsky, A. O., E-mail: alex.strek@bk.ru; Kamanin, D. V. [Joint Institute for Nuclear Research (Russian Federation); Pyatkov, Yu. V. [National Nuclear Research University MEPhI (Moscow Engineering Physics Institute) (Russian Federation); Kondratyev, N. A.; Zhuchko, V. E. [Joint Institute for Nuclear Research (Russian Federation); Ilić, S. [University of Novi Sad (Serbia); Alexandrov, A. A.; Alexandrova, I. A. [Joint Institute for Nuclear Research (Russian Federation); Jacobs, N. [University of Stellenbosch, Faculty of Military Science, Military Academy (South Africa); Kuznetsova, E. A.; Mishinsky, G. V.; Strekalovsky, O. V. [Joint Institute for Nuclear Research (Russian Federation)

    2016-12-15

    A new off-line timing method for PIN diode signals is presented which allows the plasma delay effect to be suppressed. Velocities of heavy ions measured by the new method are in good agreement within a wide range of masses and energies with velocities measured by time stamp detectors based on microchannel plates.

  12. Calculus Courses' Assessment Data

    Science.gov (United States)

    Pauna, Matti

    2017-01-01

    In this paper we describe computer-aided assessment methods used in online Calculus courses and the data they produce. The online learning environment collects a lot of time-stamped data about every action a student makes. Assessment data can be harnessed into use as a feedback, predictor, and recommendation facility for students and instructors.…

  13. 75 FR 52039 - Biweekly Notice Applications and Amendments to Facility Operating Licenses Involving No...

    Science.gov (United States)

    2010-08-24

    ... the design earthquake, the double design earthquake, the Hosgri earthquake, and the loss-of-coolant... by the Chief Administrative Judge of the Atomic Safety and Licensing Board Panel, will rule on the....m. Eastern Time on the due date. Upon receipt of a transmission, the E-Filing system time-stamps the...

  14. 75 FR 16024 - Proposed Amendment of Norton Sound Low and Control 1234L Offshore Airspace Areas; Alaska

    Science.gov (United States)

    2010-03-31

    ... aspects of the proposal. Communications should identify both docket numbers (FAA Docket No. FAA-2010-0071....'' The postcard will be date/time stamped and returned to the commenter. All communications received on... Tooksook Bay; within 74 miles of Elim and Manokotak, and within 72.5 miles of Red Dog. The Control 1234L...

  15. 7 CFR 1955.147 - Sealed bid sales.

    Science.gov (United States)

    2010-01-01

    ... Law 103-354 will accept the bid or bids which are in the best financial interest of the Government... agency under Public Law 103-354 office. All bids will be date and time stamped. Advertisements and... 7 Agriculture 14 2010-01-01 2009-01-01 true Sealed bid sales. 1955.147 Section 1955.147...

  16. On detecting the playing/non-playing activity of musicians in symphonic music videos

    NARCIS (Netherlands)

    Bazzica, A.; Liem, C.C.S.; Hanjalic, A.

    2016-01-01

    Information on whether a musician in a large symphonic orchestra plays her instrument at a given time stamp or not is valuable for a wide variety of applications aiming at mimicking and enriching the classical music concert experience on modern multimedia platforms. In this work, we propose a novel

  17. Métodos para generar trayectorias libres de colisiones en entornos multidimensionales

    OpenAIRE

    Edwin Francis Cárdenas; Luis Miguel Mendez; Jorge Sofrony Esmeral

    2011-01-01

    Reliable path-planning and generation of collision-free trajectories has become an area of active research over the past decade where the field robotics has probably been the most active area. This paper's main objective is to analyse the advantages and disadvantages of two of the most popular techniques used in collision-free trajectory generation in n-dimensional spaces. The importance of analysing such techniques within a generalised framework is evident as path-planning is used in a varie...

  18. Characterisation of the NA62 GigaTracker End of Column Demonstrator Hybrid Pixel Detector

    Science.gov (United States)

    Noy, M.; Aglieri Rinella, G.; Cotta Ramusino, A.; Fiorini, M.; Jarron, P.; Kaplon, J.; Kluge, A.; Martin, E.; Morel, M.; Perktold, L.; Poltorak, K.; Riedler, P.

    2011-11-01

    The architecture and characterisation of the NA62 GigaTracker End of Column Demonstrator Hybrid Pixel Detector (HPD) are presented. This detector must perform time stamping to 200 ps (RMS) or better, provide 300 μm pitch position information and operate with a dead time of 1% or less for 800 MHz-1 GHz beam rate. The demonstrator HPD Assembly comprises a readout chip with a test column of 45 pixels, alongside other test structures, bump bonded to a p-in-n detector 200 μm in thickness. Validation of the performance of the HPD and the time-over-threshold timewalk compensation mechanism with both beam particles and a high precision laser system was performed and is presented. Confirmation of better than the required time stamping precision has been demonstrated and subsequent work on the design of the full-scale ASIC, dubbed TDCPix, is underway. An overview of the TDCPix architecure is given.

  19. Temporal abstraction for the analysis of intensive care information

    Science.gov (United States)

    Hadad, Alejandro J.; Evin, Diego A.; Drozdowicz, Bartolomé; Chiotti, Omar

    2007-11-01

    This paper proposes a scheme for the analysis of time-stamped series data from multiple monitoring devices of intensive care units, using Temporal Abstraction concepts. This scheme is oriented to obtain a description of the patient state evolution in an unsupervised way. The case of study is based on a dataset clinically classified with Pulmonary Edema. For this dataset a trends based Temporal Abstraction mechanism is proposed, by means of a Behaviours Base of time-stamped series and then used in a classification step. Combining this approach with the introduction of expert knowledge, using Fuzzy Logic, and multivariate analysis by means of Self-Organizing Maps, a states characterization model is obtained. This model is feasible of being extended to different patients groups and states. The proposed scheme allows to obtain intermediate states descriptions through which it is passing the patient and that could be used to anticipate alert situations.

  20. Authenticity techniques for PACS images and records

    Science.gov (United States)

    Wong, Stephen T. C.; Abundo, Marco; Huang, H. K.

    1995-05-01

    Along with the digital radiology environment supported by picture archiving and communication systems (PACS) comes a new problem: How to establish trust in multimedia medical data that exist only in the easily altered memory of a computer. Trust is characterized in terms of integrity and privacy of digital data. Two major self-enforcing techniques can be used to assure the authenticity of electronic images and text -- key-based cryptography and digital time stamping. Key-based cryptography associates the content of an image with the originator using one or two distinct keys and prevents alteration of the document by anyone other than the originator. A digital time stamping algorithm generates a characteristic `digital fingerprint' for the original document using a mathematical hash function, and checks that it has not been modified. This paper discusses these cryptographic algorithms and their appropriateness for a PACS environment. It also presents experimental results of cryptographic algorithms on several imaging modalities.