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Sample records for ti-zr-v present development

  1. Beyond Ti-Zr-V: present development on thin-film coatings for beam pipes

    CERN Document Server

    Chiggiato, P

    2008-01-01

    Since 1997, Ti-Zr-V thin films have been studied to provide a solution to the problems of both pressure distribution and electron cloud build-up in beam pipes. Nowadays, this material is coated on the whole inner surface of vacuum chambers providing large pumping speed, low degassing rate and secondary electron yield. These favourable characteristics are obtained after heating in vacuum at temperatures higher than 180 °C. Unfortunately, heating at such temperatures is not always possible for the future CERN projects: in some cases, magnet designs impose lower heating temperatures; in other cases, heating is not allowed at all, as for most of the existing SPS vacuum chambers. To overcome these limitations, two lines of development have been drawn; if pursed successfully, they will allow the production of both NEG films with lower activation temperature (150 °C being our target) and films or surface treatments providing low secondary electron yield without any heating.

  2. Evaluation of Ti-Zr-V (NEG) Thin Films for their pumping speed and pumping Capacity

    International Nuclear Information System (INIS)

    Bansod, Tripti; Sindal, B K; Kumar, K V A N P S; Shukla, S K

    2012-01-01

    Deposition of NEG thin films onto the interior walls of the vacuum chambers is an advanced technique to convert a vacuum chamber from a gas source to an effective pump. These films offer considerably large pumping speed for reactive gases like CO, H 2 etc. A UHV compatible pumping speed measurement system was developed in-house to measure the pumping speed of NEG coated chambers. To inject the fixed quantity of CO and H 2 gas in pumping speed measurement set-up a calibrated leak was also developed. Stainless steel chambers were sputter coated with thin film of Ti-Zr-V getter material using varied parameters for different compositions and thickness. Pumping capacity which is a function of sorbed gas quantities was also studied at various activation temperatures. In order to optimize the activation temperature for maximum pumping speed for CO and H 2 , pumping speeds were measured at room temperature after activation at different temperatures. The experimental system detail, pumping performance of the NEG film at various activation temperatures and RGA analysis are presented.

  3. The adhesion performance of epoxy coating on AA6063 treated in Ti/Zr/V based solution

    Energy Technology Data Exchange (ETDEWEB)

    Zhu, Wen; Li, Wenfang, E-mail: mewfli@scut.edu.cn; Mu, Songlin; Yang, Yunyu; Zuo, Xi

    2016-10-30

    Highlights: • A non-chrome titanium/zirconium/vanadium-based (Ti/Zr/V) conversion coating is prepared on AA6063 at room temperature. • The Ti/Zr/V conversion coating is produced on AA6063 within 50 s. • The adhesion strength between epoxy coating and AA6063 is improved significantly after the Ti/Zr/V conversion treatment. - Abstract: An environment-friendly titanium/zirconium/vanadium-based (Ti/Zr/V) conversion coating was prepared on aluminum alloy 6063 (AA6063). The epoxy powder coatings were applied on the AA6063 samples with/without Ti/Zr/V conversion coatings via electrostatic spraying. The morphology and composition of the conversion coating were studied by scanning electron microscope (SEM) and X-ray photoelectron spectroscopy (XPS), respectively. The surface free energy components of AA6063 samples were measured by a static contact angle measuring device with Owens method. The adhesion properties of the epoxy coating on AA6063 treated with different conversion times were evaluated using a pull-off tester. The Ti/Zr/V conversion coating was mainly composed of metal oxide (TiO{sub 2}, ZrO{sub 2}, V{sub 2}O{sub 5}, Al{sub 2}O{sub 3}, etc.), metal fluoride (ZrF{sub 4}, AlF{sub 3}, etc.) and metal organic complex. The formation time of this conversion coating was reduced to 50 s. After such surface treatment, the samples' surface roughness was increased and the contact angle with water was decreased. Both the surface free energy and the work of adhesion were increased. The adhesion strength between the epoxy coating and AA6063 was enhanced significantly.

  4. Comparative study on Ti/Zr/V and chromate conversion treated aluminum alloys: Anti-corrosion performance and epoxy coating adhesion properties

    Energy Technology Data Exchange (ETDEWEB)

    Zhu, Wen; Li, Wenfang, E-mail: mewfli@163.com; Mu, Songlin; Fu, Nianqing; Liao, Zhongmiao

    2017-05-31

    Highlights: • The surface roughness and surface free energy of the AA6063 are significantly increased after TZVCC treatment. • The anti-corrosion performance of the AA6063 is effectively enhanced after TZVCC treatment. • Both the corrosion resistance and wet adhesion properties of the epoxy coating on the AA6063 are noticeably improved after TZVCC treatment. - Abstract: In this study, a Ti/Zr/V conversion coating (TZVCC) was deposited on the surface of aluminum alloy 6063 (AA6063) as an alternative of the chromate conversion coating (CCC). Both the TZVCC treated AA6063 (TZVCC/AA6063) and CCC treated AA6063 (CCC/AA6063) were characterized by scanning electron microscopy (SEM), X-ray photoelectron spectroscopy (XPS), atomic force microscope (AFM) and contact angle measuring device. The anti-corrosion performance of the TZVCC/AA6063 and CCC/AA6063 was evaluated by electrochemical measurements and neutral salt spray tests. It showed that both the surface roughness and surface free energy of the AA6063 were significantly increased after TZVCC treatment. The anti-corrosion performance of TZVCC/AA6063 was superior to that of CCC/AA6063. In addition, the effects of the TZVCC and CCC on the adhesion properties and anti-corrosion performance of epoxy coating applied on samples were examined by pull-off tests and electrochemical impedance spectroscopy (EIS). The dry, wet and recovery adhesive strengths of the epoxy coating on TZVCC treated samples (epoxy coated TZVCC/AA6063) were very close to those of epoxy coating on CCC treated ones (epoxy coated CCC/AA6063). The epoxy coated TZVCC/AA6063 showed better corrosion resistance than the epoxy coated CCC/AA6063 and epoxy coated AA6063.

  5. Develop your presentation skills

    CERN Document Server

    Theobald, Theo

    2016-01-01

    Going beyond handling nerves and presenting PowerPoint slides, the third edition of "Develop Your Presentation Skills "offers practical advice on developing a captivating presentation, constructing compelling content, and boosting self-confidence. The book includes three new chapters on delivering a "stripped down"presentation, using new media to engage with the audience, and handling being asked to present on short notice."

  6. Developing the art of scientific presentation.

    Science.gov (United States)

    Waljee, Jennifer F; Larson, Bradley P; Chang, Kate Wan-Chu; Ono, Shimpei; Holland, Amy L; Haase, Steven C; Chung, Kevin C

    2012-12-01

    Few guidelines exist regarding the most effective approach to scientific oral presentations. Our purpose is to (1) develop a standardized instrument to evaluate scientific presentations based on a comprehensive review of the available literature regarding the components and organization of scientific presentations and (2) describe the optimal characteristics of scientific presentations. At the Sixty-sixth (2011) Annual Meeting of the American Society for Surgery of the Hand, 69 presentations were evaluated by at least 2 independent observers. A rating instrument was developed a priori to examine presentation content (background, methods, results, and conclusions), presentation style (speech, structure, delivery, slide aesthetics), and overall quality. We examined correlations between reviewers' ratings of each component as well as overall perceived quality of the presentation using regression analysis. Intraclass correlation coefficients were calculated to measure the degree of variation because of reviewer disagreement and identify the aspects of presentations that contribute to overall quality. Reviewer agreement was high for presentation content, and less than 1% of variation was caused by reviewer disagreement for background, methods, and conclusions. With respect to presentation style, reviewers agreed most frequently regarding speech and slide appearance, and only 9% and 13%, respectively, of the variation was caused by reviewer disagreement. Disagreement was higher for delivery and presentation structure, and 21% of the variation was attributable to reviewer disagreement. Speaker delivery and slide appearance were the most important predictors of presentation quality, followed by the quality of the presentation of conclusions and background information. Presentation of methods and results were not associated with overall presentation quality. Distinct aspects of presentation content and style correlate with quality, which can be reliably and objectively

  7. NEG coating of the non-standard LSS vacuum chambers

    CERN Document Server

    Costa-Pinto, P

    2005-01-01

    The vacuum chambers of nearly all the warm magnets of the LHC (MBXW, MQW, MSI, MSD, etc…) will be coated with a Ti-Zr-V thin film by magnetron sputtering. The NEG coating is necessary to provide uniform pumping speed along the chambers and to suppress electron cloud instabilities and dynamic outgassing. The about 300 chambers will be coated using the existing facility, developed for the production of the standard LSS chambers, after minor modifications mainly due to the different cross sections. In order to cope with the present installation schedule, the production planning will allow processing of different families of chambers in parallel by using two or three coating systems simultaneously. After a brief introduction to the Ti-Zr-V characteristics and performances, the coating facility and strategy will be illustrated as well as the possible conflicts due to uncertainties in the planning of the experimental beam pipes and the standard LSS chambers.

  8. Food production - Present and future development

    International Nuclear Information System (INIS)

    Lamm, C.G.

    1974-01-01

    This year the joint FAO/IAEA Division of Atomic Energy in Food and Agriculture celebrates its 10th anniversary. The aim of these two United Nations organizations is to ensure that the technical services of both FAO and IAEA are fully co-ordinated and their programmes are designed to assist developing Member States to apply isotopes and radiation techniques to the solution of food and agricultural problems. More precisely, the medium-term objectives of the Joint Division are to exploit the potential of nuclear techniques in research and development for increasing and stabilizing agricultural production, improving food quality, protecting agricultural products from spoilage and losses and minimizing pollution of food and the agricultural environment. This account of what radioisotopes can do for man in the agricultural field is therefore to a great extent a review of the activities of the Joint Division and a prediction of its future fields of emphasis, especially in the light of the present long-range and world-wide food crisis. (author)

  9. [Homosexual parenthood and child development: present data].

    Science.gov (United States)

    Fond, G; Franc, N; Purper-Ouakil, D

    2012-02-01

    The aim of this article is to provide an overview of existing studies on gay and lesbian parenthood and child development. Although 200,000 to 300,000 children could be concerned in 2010 in France, there is a lack of research on this issue in our country. Research among children raised by homosexual parents involves methodological issues, such as defining homosexual families, sampling cases and controls, and choosing structured or semi-structured evaluations. The fact that homosexual marriage, adoption and insemination are not presently legal in France could explain that only one study has been conducted in France in 2000 among 58 children raided by homosexual parents. This study concluded that these children did not show an increased rate of behavior or anxiety disorders. Concerns about lesbian parenting have focused on the absence of a father, the homosexual orientation of the mother, and their negative consequences on the development of the children. Research on parenting and child rearing has repeatedly compared lesbian and heterosexual families, and in the last 30 years a growing body of studies on lesbian parents and the development of their children has been published. Studies about child development, sexual orientation, gender identity, gender role behavior, emotional/behavioral development, social relationships and cognitive functioning showed no difference between children of lesbian mothers and those of heterosexual parents. Likewise, parental functioning, the mothers' psychological health and maternal skills were not significantly different among lesbian mothers than among heterosexual mothers. In studies concerning gay fathers, findings generally indicate no differences in sexual orientation, socialization, or psychological outcomes in children of gay fathers compared to children of heterosexual fathers. However, the first study on the adult attachment style dimensions of adult women who had gay or bisexual fathers suggested that they were

  10. Recent Developments and Present Status of Telepathology

    Directory of Open Access Journals (Sweden)

    K. Kayser

    2000-01-01

    Full Text Available Telepathology which is the diagnostic work of a pathologist at a distance has been developed to routine application within the last ten years. It can be classified in relation to application, technical solutions, or performance conditions. Diagnostic pathology performance distinguishes primary diagnosis (for example, frozen section statement from secondary diagnosis (for example, expert consultation and quality assurance (diagnostic accuracy, continuous education and training. Applications comprise (a frozen section service; (b expert consultations; (c remote control measurements; and (d education and training. The technical solutions distinguish active (remote control, live imaging systems from passive (conventional microscope handling, static imaging, and the performance systems with interactive (on‐line, live imaging use from those with passive (off‐line, static imaging practice. Intra‐operative frozen section service is mainly performed with remote control systems; whereas expert consultations and education/training are commonly based upon Internet connections with static imaging in an off‐line mode. The image quality, transfer rates, and screen resolution of active and passive telepathology systems are sufficient for an additional or primary judgment of histological slides and cytological smears. From the technical point of view, remote control telepathology requires a fast transfer and at least near on‐line judgement of images, i.e., image acquisition, transfer and presentation can be considered one performance function. Thus, image size, line transfer rate and screen resolution define the practicability of the system. In expert consultation, the pixel resolution of images and natural color presentation are the main factors for diagnostic support, whereas the line transfer rate is of minor importance. These conditions define the technical compartments, especially size and resolution of camera and screen. The performance of

  11. Present status of HTGR research and development

    International Nuclear Information System (INIS)

    1992-08-01

    This report briefly describes the progress of the construction of the High Temperature Engineering Test Reactor (HTTR), Research and Development (R and D) on the advanced technologies for the High Temperature Gas-cooled Reactors (HTGRs) and international cooperation in the Japan Atomic Energy Research Institute (JAERI) in 1991. (J.P.N.)

  12. Present state and development of positron tomographs

    International Nuclear Information System (INIS)

    Allemand, R.; Gariod, R.; Laval, M.; Tournier, F.

    1979-01-01

    This document presents the main characteristics of positron tomographs and analyses the relative importance of the parameters to be taken into consideration in the design of a tomograph: on the one hand, the physical parameters linked to the measurement of the annihilation photons by time coincidence and, on the other, the geometrical and technological parameters of prime importance in minimizing the many spurious effects. The last part endeavours to show this sort of instrumentation has evolved. Using the results obtained in our laboratory by mathematical simulation, the expected advantages are presented on the picture quality of the time of flight measurement of annihilation photons. Where the physical aspects of this method are concerned, the advantage of using cesium fluoride as scintillator is demonstrated [fr

  13. Habenula circuit development: past, present and future

    Directory of Open Access Journals (Sweden)

    Carlo Antonio Beretta

    2012-04-01

    Full Text Available The habenular neural circuit is attracting increasing attention from researchers in fields as diverse as neuroscience, medicine, behavior, development and evolution. Recent studies have revealed that this part of the limbic system in the dorsal diencephalon is involved in reward, addiction and other behaviors and its impairment is associated with various neurological conditions and diseases. Since the initial description of the Dorsal Diencephalic Conduction system (DDC with the habenulae in its center at the end of the 19th century, increasingly sophisticated techniques have resolved much of its anatomy and have shown that these pathways relay information from different parts of the forebrain to the tegmentum, midbrain and hindbrain. The first part of this review gives a brief historical overview on how the improving experimental approaches have allowed the stepwise uncovering of much of the architecture of the habenula circuit as we know it today. Our brain distributes tasks differentially between left and right and it has become a paradigm that this functional lateralization is a universal feature of vertebrates. Moreover, task dependent differential brain activities have been linked to anatomical differences across the left-right axis in humans. A good way to further explore this fundamental issue will be to study the functional consequences of subtle changes in neural network formation, which requires that we fully understand DDC system development. As the habenular circuit is evolutionarily highly conserved, researchers have the option to perform such difficult experiments in more experimentally amenable vertebrate systems. Indeed, research in the last decade has shown that the zebrafish is well suited for the study of DDC system development and the phenomenon of functional lateralization. We will critically discuss the advantages of the zebrafish model, available techniques and others that are needed to fully understand habenular circuit

  14. Present and future development at Ganil

    International Nuclear Information System (INIS)

    Ferme, J.

    1988-01-01

    GANIL has been in operation since January 1983. During this period beams from Carbon to Xenon have been available continuously for physics. There is now a demand to extend the ion range up to uranium, and to increase the beam intensity above the present level of about 3 microamperes with light ions. The corresponding modifications of the machine have been studied and will be made in the near future. Progress in ion sources, beam diagnostics, computer control is reported. Speculative considerations on the distant future are discussed

  15. Presentations

    International Nuclear Information System (INIS)

    2007-01-01

    The presented materials consist of presentations of international workshop which held in Warsaw from 4 to 5 October 2007. Main subject of the meeting was progress in manufacturing as well as research program development for neutron detector which is planned to be placed at GANIL laboratory and will be used in nuclear spectroscopy research

  16. Presentations

    International Nuclear Information System (INIS)

    2007-01-01

    The PARIS meeting held in Cracow, Poland from 14 to 15 May 2007. The main subjects discussed during this meeting were the status of international project dedicated to gamma spectroscopy research. The scientific research program includes investigations of giant dipole resonance, probe of hot nuclei induced in heavy reactions, Jacobi shape transitions, isospin mixing and nuclear multifragmentation. The mentioned programme needs Rand D development such as new scintillations materials as lanthanum chlorides and bromides as well as new photo detection sensors as avalanche photodiodes - such subjects are also subjects of discussion. Additionally results of computerized simulations of scintillation detectors properties by means of GEANT- 4 code are presented

  17. Professional Presentation Skills Development in a Graduate Nursing Program.

    Science.gov (United States)

    Fowler, Debra L; Jones, Deborah J

    2015-12-01

    Expert communication skills are essential for nurse leaders to effectively influence health care. Because effective communication is a learned process, the curriculum should promote the development of presentation skills. An educational strategy was designed to promote the development of effective presentation skills for learners in the Nursing Leadership and Administration (NLA) track of the master's in nursing curriculum. Sixteen learners in the NLA cohort were participants in a three-session presentation skills workshop. Following a baseline presentation, participants were taught presentation strategies and skills. Expert evaluators and learner self-assessments rated their presentation skills. Analysis of evaluators' ratings showed statistically significant (p presentation effectiveness. Analysis of learner self-ratings showed a statistically significant (p = .008) increase in perceived effectiveness of overall presentation skills. This unique educational intervention improved nurse leaders' presentation skills. Faculty found that the professional presentation skill workshop was important to learners' success. Copyright 2015, SLACK Incorporated.

  18. Presentation

    Directory of Open Access Journals (Sweden)

    Eduardo Vicente

    2013-06-01

    effectivities more than a number of fixed essential characteristics. Luiz Artur Ferrareto (UFRGS, undertaking a theoretical proposal for categorizing radio content in four different levels of planning (segment, form, programming and content itself tries to “compare and contrast the practices of Brazilian commercial broadcasting companies to those used on the radio in the United States, a reference market for our national entrepreneurs”. Madalena Oliveira (University of Minho focuses on the current stage of communication researches in Portugal reflecting on the challenges for studying a culture based on listening in times of looking. Marko Ala-Fossi, (University of Tampere beginning with the statement that “radio evolution greatly depends not only on the cultural context of a country but also on the whole social, political, economic development of societies” gives us a projection on radio development around the world for the next decades. Closing the dossier, Rafael Duarte Oliveira Venancio (UFU assuming radio as language by definition and not as a device understands it as a section and an operating model in such language as it intersects the world. Another six articles, not enrolled in the dossier, round the edition off. Fernando de Tacca debates the category of “photocine” recurring to three recent Spanish productions. Gustavo Souza investigates the possibility of identifying a point of view in documentary movies while establishing a debate that joins the materialities of image and sound with the subjectivity resulting from interpretation. Vinicius Bandeira develops on the special duplicity present in the movies between what is and what is not subsumed by the camera. Neide Jallageas proposes the study of visual communication design from the first modelings, attempting especially to the radical propositions from the early XXth century avant-garde movement. Gilson Schwartz debates on the impact from the distribution of videogames as hegemonic cultural practice in

  19. PRESENT STATE OF DEVELOPMENT OF AUTOMATED ELECTRIC POWER SUPPLY

    Science.gov (United States)

    The present state of development of automated electric power supply in the USSR is discussed. The electric power supply is treated in relation to the...Developments in the area of creation of complex systems of electric power supply for various branches of industry are included.

  20. A Microcomputer-Based Interactive Presentation Development System.

    Science.gov (United States)

    Moreau, Dennis R.; Dominick, Wayne D.

    1988-01-01

    Reviews research and development projects sponsored by the National Aeronautics and Space Administration (NASA) that address microcomputer-based support for instructional activities at the University of Southwestern Louisiana. Highlights include a graphics project, local area networks, and the Interactive Presentation Development System, which is…

  1. Present status of research and development on underground disposal

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1994-11-01

    Power Reactor and Nuclear Fuel Development Corporation published the technical report `Research and development of the formation disposal of high level radioactive waste` 1991 in 1992, summarizing the results of the research and development of the formation disposal which have been advanced by dividing into three parts, that is, the investigation and research of geological environment conditions, the research and development of disposal technologies, and the research on the performance evaluation. Based on the subjects pointed out during the process of making the technical report, the results of evaluation by the state, and the opinions of those concerned, the efforts are exerted toward the second summarization expected in about 2000. By informing the present state of the research and development, in order to accept the criticism and advice, this book was published. The way of thinking and the method of advancing of the research and development of formation disposal, the present state of the research on geological environment conditions, disposal technologies and the performance evaluation are described. Also the present state of the research on stratum science in Tono and Kamaishi mines and others is reported. (K.I.).

  2. Present status of research and development on underground disposal

    International Nuclear Information System (INIS)

    1994-11-01

    Power Reactor and Nuclear Fuel Development Corporation published the technical report 'Research and development of the formation disposal of high level radioactive waste' 1991 in 1992, summarizing the results of the research and development of the formation disposal which have been advanced by dividing into three parts, that is, the investigation and research of geological environment conditions, the research and development of disposal technologies, and the research on the performance evaluation. Based on the subjects pointed out during the process of making the technical report, the results of evaluation by the state, and the opinions of those concerned, the efforts are exerted toward the second summarization expected in about 2000. By informing the present state of the research and development, in order to accept the criticism and advice, this book was published. The way of thinking and the method of advancing of the research and development of formation disposal, the present state of the research on geological environment conditions, disposal technologies and the performance evaluation are described. Also the present state of the research on stratum science in Tono and Kamaishi mines and others is reported. (K.I.)

  3. Present status of nuclear development in Japan and international cooperation

    International Nuclear Information System (INIS)

    Oyama, Akira

    1994-01-01

    An overview of the current status of nuclear research in Japan is presented. The importance of research and developments in the fields of nuclear fuel recycling by means of fast breeders and nuclear fusion is emphasised. Nonproliferation, nuclear disarmament and international cooperation are also promoted. 2 figs

  4. Non-destructive Depth Profiling of the Activated Ti-Zr-V Getter by Means of Excitation Energy Resolved Photoelectron Spectroscopy

    Czech Academy of Sciences Publication Activity Database

    Pavluch, J.; Zommer, L.; Mašek, K.; Skála, T.; Šutara, F.; Nehasil, V.; Píš, I.; Polyak, Yaroslav

    2010-01-01

    Roč. 26, č. 2 (2010), s. 209-215 ISSN 0910-6340 Institutional research plan: CEZ:AV0Z40400503 Keywords : non-evaporable getter materials * XPS methods Subject RIV: CF - Physical ; Theoretical Chemistry Impact factor: 1.465, year: 2010

  5. Nuclear model developments in FLUKA for present and future applications

    Directory of Open Access Journals (Sweden)

    Cerutti Francesco

    2017-01-01

    Full Text Available The FLUKAS code [1–3] is used in research laboratories all around the world for challenging applications spanning a very wide range of energies, projectiles and targets. FLUKAS is also extensively used for in hadrontherapy research studies and clinical planning systems. In this paper some of the recent developments in the FLUKAS nuclear physics models of relevance for very different application fields including medical physics are presented. A few examples are shown demonstrating the effectiveness of the upgraded code.

  6. Nuclear model developments in FLUKA for present and future applications

    Science.gov (United States)

    Cerutti, Francesco; Empl, Anton; Fedynitch, Anatoli; Ferrari, Alfredo; Ruben, GarciaAlia; Sala, Paola R.; Smirnov, George; Vlachoudis, Vasilis

    2017-09-01

    The FLUKAS code [1-3] is used in research laboratories all around the world for challenging applications spanning a very wide range of energies, projectiles and targets. FLUKAS is also extensively used for in hadrontherapy research studies and clinical planning systems. In this paper some of the recent developments in the FLUKAS nuclear physics models of relevance for very different application fields including medical physics are presented. A few examples are shown demonstrating the effectiveness of the upgraded code.

  7. Developing a "clinical presentation" curriculum at the University of Calgary.

    Science.gov (United States)

    Mandin, H; Harasym, P; Eagle, C; Watanabe, M

    1995-03-01

    Currently, medical curricula are structured according to disciplines, body systems, or clinical problems. Beginning in 1988, the faculty of the University of Calgary Faculty of Medicine (U of C) carefully evaluated the advantages and disadvantages of each of these models in seeking to revise their school's curriculum. However, all three models fell short of a curricular structure based on current knowledge and principles of adult learning, clinical problem solving, community demands, and curriculum management. By 1991, the U of C had formulated a strategic plan for a revised curriculum structure based on the way patients present to physicians, and implementation of this plan has begun. In creating the new curriculum, 120 clinical presentations (e.g., "loss of consciousness/syncope") were defined and each was assigned to an individual or small group of faculty for development based on faculty expertise and interest. Terminal objectives (i.e., "what to do") were defined for each presentation to describe the appropriate clinical behaviors of a graduating physician. Experts developed schemes that outlined how they differentiated one cause (i.e., disease category) from another. The underlying enabling objectives (i.e., knowledge, skills, and attitudes) for reaching the terminal objectives for each clinical presentation were assigned as departmental responsibilities. A new administrative structure evolved in which there is a partnership between a centralized multidisciplinary curriculum committee and the departments. This new competency-based, clinical presentation curriculum is expected to significantly enhance students' development of clinical problem-solving skills and affirms the premise that prudent, continuous updating is essential for improving the quality of medical education.

  8. The gas turbine: Present technology and future developments

    International Nuclear Information System (INIS)

    Minghetti, E.

    1997-03-01

    The gas turbine is the most widely used prime mover all over the world for either power generation or mechanical drive applications. The above fact is due to the recent great improvements that have been done especially in terms of efficiency, availability and reliability. The future for gas turbine technological development looks very promising. In fact, although tremendous growth has already taken place, there is still the potential for dramatic improvements in performance. Compared with the competitive prime movers (conventional steam power plants and reciprocating piston engines) the gas turbine technology is younger and still following a strong growth curve. The coming decades will witness the continued increasing in turbine inlet temperature, the development of new materials and refrigeration systems and the commercialization of inter cooled system and steam cooled turbines. With the very soon introduction of the G and H technology, expected single and combined cycle efficiencies for heavy duty machines are respectively 40% and 60%, while maintaining 'single digit' levels in pollutant emissions. In this report are given wide information on gas turbine present technology (Thermodynamics, features, design, performances, emission control, applications) and are discussed the main lines for the future developments. Finally are presented the research and technological development activities on gas turbine of Italian National Agency for new Technology Energy and the Environment Energy Department

  9. Present state of Japan Nuclear Ship Development Agency

    International Nuclear Information System (INIS)

    Takada, Yoshio

    1981-01-01

    The Japan Nuclear Ship Development Agency held the annual report meeting on April 8, 1981. The main contents were the plan of research and development of nuclear ships hereafter, the present state of the repair works for the nuclear ship ''Mutsu'', the progress of the selection of the new home port and others. In the last year, the function of research was given to the Agency by the revision of the related law. The full-scale repair works for Mutsu were started in August, 1980, and various equipments and shields in the containment vessel and the upper shields of the containment vessel have been removed. Subsequently, new shields are being installed. According to the report by the committee of nuclear ship research and development, the development of Mutsu, which is valuable as the experimental ship, is continued. Moreover, it is proposed to do the research and development of an improved marine nuclear plant for the purposes of securing the economic efficiency, the proving of the reliability of nuclear merchant ships, and the establishment of safety. As the home port for Mutsu, the new port will be constructed on the open sea side in Aomori Prefecture, and as a candidate, Sekine beach in Mutsu City was named. Till the completion of the new home port, Mutsu will be berthed in Ominato home port. The conditions for entering and berthing in Ominato port will be decided later. (Kako, I.)

  10. Disorders of sex development presenting as unilateral cryptorchidism

    DEFF Research Database (Denmark)

    Ostergren, Peter; Juul, Anders; Azawi, Nessn H

    2013-01-01

    Abstract Disorders of sex development (DSD) present in different forms but, in most cases, with visible anomalies of the external genitalia. The diagnosis of DSD can have a vast impact on an individual; in addition to concerns about fertility and a higher risk of neoplasia, it may have severe...... psychosocial impact on the patient. This report presents two apparently healthy cases referred for operation because of unilateral undescended testis. In these two patients, uterine remnants were found during the operation, and underlying DSD conditions were unexpectedly diagnosed. One patient had a 45,X/46,XY...... mosaic karyotype, while the second patient had persistent müllerian duct syndrome, probably due to an anti-müllerian hormone receptor defect. Both conditions are extremely rare, but the findings reinforce that DSD should be considered in patients with cryptorchidism, especially if other clinical signs...

  11. Development and validation of the Efficacious Self-Presentation Scale.

    Science.gov (United States)

    Laghi, Fiorenzo; Pallini, Susanna; D'Alessio, Maria; Baiocco, Roberto

    2011-01-01

    A new self-report measure of adolescent's self-presentation is described. The self-report scale was administered to 760 16-19-year-old subjects. Results of a factor analysis supported 6 identifiable factors reflecting different concepts, theoretically discussed, related to self-presentation: ability to regulate self-image, social sensitivity, body self-confidence, social self-confidence, social openness, and social desirability. The scale showed good convergent validity and internal consistency. Assertive tactics were predicted through ability to regulate self-image, social self-confidence, and social openness, whereas defensive tactics were predicted only through social openness and social sensitivity. The implications of the findings for future theoretical and empirical development of research in this field are discussed.

  12. Present status of development of uranium resources in foreign countries

    International Nuclear Information System (INIS)

    1983-10-01

    The book with the same title as this was published in 1981. Thereafter, the necessity to correct the contents arose, such as the remarkable change in uranium market condition and the change of uranium resource policy in Australia accompanying the change of regime, accordingly, the revision was carried out by adding more new information. As the main sources of the information collected in this book, 25 materials are shown. The confirmed resources of uranium in the free world as of the beginning of 1981 amounted to 2,293,000 t U, and the estimated additional resources were 2,720,000 t U. The political system and uranium policy, the present status of uranium export, the quantity of resources and the estimated amount of deposits, the uranium production and the status of uranium exploration and development of 25 foreign countries are reported. Japan has carried out uranium development activities in Australia, Canada, Niger, Gabon, Zambia and so on. (Kako, I.)

  13. Present status of uranium resource development in foreign countries, 1984

    International Nuclear Information System (INIS)

    1984-12-01

    The book of the same title as this one was published in 1983. Since then, the situation requiring the correction of the contents, such as the correction of uranium resource policy in various countries accompanying the change of uranium market condition and the change of uranium policy in Australia due to the political situation, has occurred, consequently, the revision has been made adding these new information. The confirmed resources of uranium and the resources of uranium to be added by estimation in the free world are tabulated. About each country, the organization and policy, the policy of exporting uranium and the present status of the export, the quantity of uranium resources, the production of uranium, the state of exploration and development and so on are reported. Japan has taken part in the development of uranium resources in Australia, Canada, Gabon, Zambia, Morocco, Guinea, Mali and so on. (Kako, I.)

  14. Photovoltaics in Switzerland - Present situation and prospects for further development

    International Nuclear Information System (INIS)

    Nowak, S.; Gutschner, M.

    2009-01-01

    This article takes a look at the contributions made by Switzerland in the areas of research, innovation and production technologies for photovoltaics. The intensive developments that can be noted in the Swiss photovoltaics area are commented on. Growth rates in the photovoltaics industry are quoted and commented on. The state-of-the-art and present trends are discussed, including organic and inorganic solar cells and concentrating systems. The author comments on the many technologies currently being worked on, with newer technologies catching up with the more traditional crystalline silicon systems. Balance-of-system products, such as inverters, cabling systems and controllers are briefly discussed. Also, increased interest and developments in monitoring systems for the power produced by the solar installations is noted. Swiss research and production facilities are commented on. Price-parity for solar power and its future effect on the European and Swiss solar markets is discussed

  15. Engaging the audience: developing presentation skills in science students.

    Science.gov (United States)

    Stuart, Ann E

    2013-01-01

    This article describes a graduate class in presentation skills ("PClass") as a model for how a class with similar objectives, expectations and culture might be mounted for undergraduates. The required class is given for students in neuroscience and physiology programs at the University of North Carolina at Chapel Hill; I describe the class in the years I led it, from 2003-2012. The class structure centered on peer rehearsal, critiquing of PowerPoint, and chalk talks by the students; video-recording of student talks for later review by the student with the instructor; and presentation of polished talks in a formal setting. A different faculty visitor to the class each week gave the students a variety of perspectives. The students also gained insight into their own evolving skills by discussing the strengths and weaknesses of seminars given by visitors to the campus. A unique feature of the class was collaboration with a professional actor from the University's Department of Dramatic Arts, who helped the students develop techniques for keeping the attention of an audience, for speaking with confidence, and for controlling nervousness. The undergraduate campus would be expected to lend itself to this sort of interdisciplinary faculty cooperation. In addition, students worked on becoming adept at designing and presenting posters, introducing speakers graciously and taking charge of the speaker's question session, and speaking to a lay audience.

  16. Engaging the Audience: Developing Presentation Skills in Science Students

    Science.gov (United States)

    Stuart, Ann E.

    2013-01-01

    This article describes a graduate class in presentation skills (“PClass”) as a model for how a class with similar objectives, expectations and culture might be mounted for undergraduates. The required class is given for students in neuroscience and physiology programs at the University of North Carolina at Chapel Hill; I describe the class in the years I led it, from 2003–2012. The class structure centered on peer rehearsal, critiquing of PowerPoint, and chalk talks by the students; video-recording of student talks for later review by the student with the instructor; and presentation of polished talks in a formal setting. A different faculty visitor to the class each week gave the students a variety of perspectives. The students also gained insight into their own evolving skills by discussing the strengths and weaknesses of seminars given by visitors to the campus. A unique feature of the class was collaboration with a professional actor from the University’s Department of Dramatic Arts, who helped the students develop techniques for keeping the attention of an audience, for speaking with confidence, and for controlling nervousness. The undergraduate campus would be expected to lend itself to this sort of interdisciplinary faculty cooperation. In addition, students worked on becoming adept at designing and presenting posters, introducing speakers graciously and taking charge of the speaker’s question session, and speaking to a lay audience. PMID:24319389

  17. Drug development against tuberculosis: Past, present and future.

    Science.gov (United States)

    Vasava, Mahesh S; Bhoi, Manoj N; Rathwa, Sanjay K; Borad, Mayuri A; Nair, Sneha G; Patel, Hitesh D

    2017-10-01

    Infection of Mycobacterium tuberculosis (MTB) was observed as early as 5000 years ago with evidence, which is a primeval enemy of the humanoid race. MTB is the pathogen which is responsible for causing the infectious disease tuberculosis; it remains a major cause of morbidity and mortality in poor low-income countries as well as in developing countries because of non-availability of reliable laboratory facilities. The current treatment for drug-resistant tuberculosis (TB) is lengthy, complex, and connected with severe harmful side effects and poor outcomes. The present cure against tuberculosis has substantial restrictions, in terms of their efficiency, side-effect outline, and complication of handling. Furthermore, the emergence of multi-drug resistant tuberculosis (MDR-TB) outbreaks during the 1990s and additionally in recent times the vast deadly strains of extensively drug-resistant tuberculosis (XDR-TB) and totally drug resistance tuberculosis (TDR-TB) is hampering efforts to control and manage tuberculosis (TB). As a result, novel methodologies for the treatment of multi-drug-resistant and extensive drug-resistant tuberculosis (TB) are severely desired. A number of new potential anti-tuberculosis drug candidates with novel modes of action have been entered in clinical trials in recent years. These agents are most likely to be effective against resistant strains. The treatment landscape is beginning to shift, with the recent approvals by Food and Drug Administration to the new TB drugs bedaquiline and delamanid. Also, the pipeline of potential new treatments has been fulfilled with several compounds in clinical trials or preclinical development with promising activities against sensitive and resistant MTB bacteria. An additional new chemical entity is also under development. The already existing drugs with their suggested mode of treatment as well as new probable anti-tuberculosis drug moieties which are at present in the pipeline has been summarized in this

  18. Monitoring osseointegration and developing intelligent systems (Conference Presentation)

    Science.gov (United States)

    Salvino, Liming W.

    2017-05-01

    Effective monitoring of structural and biological systems is an extremely important research area that enables technology development for future intelligent devices, platforms, and systems. This presentation provides an overview of research efforts funded by the Office of Naval Research (ONR) to establish structural health monitoring (SHM) methodologies in the human domain. Basic science efforts are needed to utilize SHM sensing, data analysis, modeling, and algorithms to obtain the relevant physiological and biological information for human-specific health and performance conditions. This overview of current research efforts is based on the Monitoring Osseointegrated Prosthesis (MOIP) program. MOIP develops implantable and intelligent prosthetics that are directly anchored to the bone of residual limbs. Through real-time monitoring, sensing, and responding to osseointegration of bones and implants as well as interface conditions and environment, our research program aims to obtain individualized actionable information for implant failure identification, load estimation, infection mitigation and treatment, as well as healing assessment. Looking ahead to achieve ultimate goals of SHM, we seek to expand our research areas to cover monitoring human, biological and engineered systems, as well as human-machine interfaces. Examples of such include 1) brainwave monitoring and neurological control, 2) detecting and evaluating brain injuries, 3) monitoring and maximizing human-technological object teaming, and 4) closed-loop setups in which actions can be triggered automatically based on sensors, actuators, and data signatures. Finally, some ongoing and future collaborations across different disciplines for the development of knowledge automation and intelligent systems will be discussed.

  19. Present status of low-Z coating development in JAERI

    International Nuclear Information System (INIS)

    Nakamura, K.; Abe, T.; Obara, K.; Murakami, Y.

    1986-01-01

    In the JT-60 at JAERI, TiC-coated molybdenum and TiC-coated Inconel tiles are currently used as plasma interactive components. They have already been subjected to initial ohmic heating experiments and exhibited good adhesion characteristics under high heat flux conditions. The present article reviews a JAERI's coating development program for JT-60 experiments currently under way and for the next-step experiments. The program includes development and performance tests of the TiC-coated tiles, development of an in-situ coating technique for the repair of damaged surface of the tiles, and research on carbonization. Stress is laid on thermal shock and thermal fatigue tests of these coatings. In the thermal tests, adhesion between low-Z coatings and bulk materials have been investigated under high heat irradiation. TiC and TiN are used as coating material while Mo and Inconel 625 are employed as bulk material. Results are shown in this report concerning calculated temperature elavation of TiC/TiN/Mo due to hydrogen beam irradiation. As regards the irradiation time required for the melting of the substrate, experimental results mostly agree with calculations. Almost all coatings investigated are not exfoliated from the substrate until the melting of the substrate. (Nogami, K.)

  20. Present and future radioactive nuclear beam developments at Argonne

    International Nuclear Information System (INIS)

    Decrock, P.

    1996-01-01

    A scheme for building an ISOL-based radioactive nuclear beam facility at the Argonne Physics Division, is currently evaluated. The feasibility and efficiency of the different steps in the proposed production- and acceleration cycles are being tested. At the Dynamitron Facility of the ANL Physics Division, stripping yields of Kr, Xe and Ph beams in a windowless gas cell have been measured and the study of fission of 238 U induced by fast neutrons from the 9 Be(dn) reaction is in progress. Different aspects of the post-acceleration procedure are currently being investigated. In parallel with this work, energetic radioactive beams such as 17 F, 18 F and 56 Ni have recently been developed at Argonne using the present ATLAS facility

  1. The CAREM project: Present status and development activities

    International Nuclear Information System (INIS)

    Boado Magan, H.J.; Ordonez, J.P.; Hey, A.

    1997-01-01

    The CAREM Project is a low power NPP of 25 Mwe, with an integrated self pressurized primary system. The cooling of the primary system is of the natural circulation type and several passive safety systems are included. The owner of the Project is Argentina's CNEA (Comision Nacional de Energia Atomica) and its associated company, INVAP, is the main contractor. The present status of the CAREM Project is presented. The possible evolution of the CAREM project is mentioned in relation with a new containment design. A short description of the Experimental Facilities, listed below, already in operation and under construction are also included: CAPCN High Pressure Loop. Natural convection loop to verify dynamic response and critical heat flux; RA-8. Critical Facility, designed and constructed for the CAREM Project (that may be used as a general uses facility); RPV lnternals. The whole assembly of absorbent rods, connecting rods and the rode guides are being constructed in a 1:1 scale. The aims of this experimental facility are vibration analysis and manufacturing parameters definitions. Control Drive Mechanisms. A series of verification and tests are being carried out on these within RPV Hydraulically driven mechanisms. Other development activities are mentioned in relation with the thermalhydraulics, Steam Generators and Control. (author)

  2. Present status of food irradiation and trend of its development

    International Nuclear Information System (INIS)

    Maha, Munsiah

    1998-01-01

    Food irradiation has been studied, tested and evaluated intensively for more than 40 years, and at present, this technology has been taking-off for commercial use in many countries. Some 40 countries have approved its application for various food items on groups of food, and about 60 commercial irradiators have been providing irradiation service for food in 29 countries. In 1983, Codex General Standard for Irradiated Food with average irradiation dose limit not exceeding 10 kGy. The latest WHO press release on September 1997 stated that the maximum 10 kGy limit should not be there, since scientific evidences indicated that food irradiated even up to 75 kGy was safe to be consumed, as long as the sensory quality was acceptable and pathogenic organisms had been killed. The development of food irradiation in advanced countries, especially in USA is very significant lately, and hopefully this will be followed by other countries. In Indonesia, application of this technology has been approved since 1987, and six items or groups of food have been cleared for commercial irradiation. Further development and introduction of the technology are still needed to widen its application and to increase public awareness through harmonization of regulations among countries and dissemination of information. In addition, irradiation techniques for some specific purpose using either low dose, medium or high doses should be established to support effective, efficient and economical application. (author)

  3. Present Status and Future Developments in Proton Therapy

    International Nuclear Information System (INIS)

    Smith, Alfred R.

    2009-01-01

    Within the past few years, interest in proton therapy has significantly increased. This interest has been generated by a number of factors including: 1) the reporting of positive clinical results using proton beams; 2) approval of reimbursement for delivery of proton therapy; 3) the success of hospital-based proton therapy centers; and 4) the availability of modern, integrated proton therapy technology for hospital-based facilities. In the United States, this increased interest has occurred particularly at the level of smaller academic hospitals, community medical centers, and large private practices; however, interest from large academic centers continues to be strong. Particular interest exists regarding smaller and less-expensive proton therapy systems, especially the so-called 'single-room' systems. In this paper, the advantages and disadvantages of 1-room proton therapy systems will be discussed. The emphasis on smaller and cheaper proton therapy facilities has also generated interest in new proton-accelerating technologies such as superconducting cyclotrons and synchrocyclotrons, laser acceleration, and dielectric-wall accelerators. Superconducting magnets are also being developed to decrease the size and weight of isocentric gantries. Another important technical development is spot-beam scanning, which offers the ability to deliver intensity-modulated proton treatments (IMPT). IMPT has the potential to provide dose distributions that are superior to those for photon intensity modulation techniques (IMXT) and to improve clinical outcomes for patients undergoing cancer therapy. At the present time, only two facilities--one in Europe and one in the United States--have the ability to deliver IMPT treatments, however, within the next year or two several additional facilities are expected to achieve this capability.

  4. Present Status of the ILC Project and Development

    Energy Technology Data Exchange (ETDEWEB)

    Ross, M.; /Fermilab; Walker, N.; /DESY; Yamamoto, A.; /KEK, Tsukuba

    2011-09-01

    The Technical Design of the International Linear Collider (ILC) Project will be finished in late 2012. The Technical Design Report (TDR) will include a description of the updated design, with a cost estimate and a project plan, and the results of research and development (R & D) done in support of the ILC. Results from directed ILC R & D are used to reduce the cost and risk associated with the ILC design. We present a summary of key challenges and show how the global R & D effort has addressed them. The most important activity has been in pursuit of very high gradient superconducting RF linac technology. There has been excellent progress toward the goal of practical industrial production of niobium sheet-metal cavities with gradient performance in excess of 35 MV/m. In addition, three purpose-built beam test facilities have been constructed and used to study and demonstrate high current linac performance, electron-cloud beam dynamics and precision beam control. The report also includes a summary of component design studies and conventional facilities cost optimization design studies.

  5. Lifelong Education (Learning) in China: Present Situation and Development Trends

    Science.gov (United States)

    Zhang, Zhupeng

    2009-01-01

    Based on the historic background and development of lifelong education (learning) in China, this paper introduces major developments of lifelong education (learning) that have been achieved through adopting a series of measures under policies issued by the Chinese government since the 1990s. Throughout the decades, efforts have been made to…

  6. Isobutane/olefin alkylation - present state and recent developments

    Energy Technology Data Exchange (ETDEWEB)

    Feller, A.; Lercher, J.A. [Inst. fuer Technische Chemie, Technische Univ. Muenchen (Germany)

    2002-12-01

    Isobutane/alkene alkylation is reviewed with respect to recent process developments based on liquid and solid acid catalysts. The reaction mechanism and its consequences for both liquid and solid acid based processes is briefly discussed. Established liquid acid catalyzed processes are introduced followed by the description of new processes based on solid acids, which are currently under development. (orig.)

  7. Present and future prospects of seaweeds in developing functional foods.

    Science.gov (United States)

    Mendis, Eresha; Kim, Se-Kwon

    2011-01-01

    There has been a combined effort among scientists to explore and utilize varying food sources to develop functional foods to cater the ever-increasing demand from the consumers, who seek health-promoting roles of dietary compounds. Considering the diversity of biochemicals in seaweeds that are capable of exerting bioactivities, a growing trend is developing across globe to employ seaweeds in functional food development. Proteins, peptides, amino acids, polysaccharides, phenolics, lipids, vitamins, and minerals in seaweeds and their functional properties provide insights into the success of potential functional food products that can be developed utilizing seaweeds. However, several factors need to be taken into consideration in designing seaweed-based functional foods to obtain the market success. This chapter elaborates on the prospects of seaweeds in developing seaweed-based functional food products. Copyright © 2011 Elsevier Inc. All rights reserved.

  8. Developing-world disaster research: present evidence and future priorities.

    Science.gov (United States)

    Roy, Nobhojit; Thakkar, Purvi; Shah, Hemant

    2011-06-01

    The technology and resource-rich solutions of the developed world may not be completely applicable to or replicable in disasters occurring in the developing world. With the current looming hazards of pandemics, climate change, global terrorism and conflicts around the world, policy makers and governments will need high-quality scientific data to make informed decisions for preparedness and mitigation. The evidence on disasters in peer-reviewed journals about the developing world was examined for quality and quantity in this systematic review. PubMed was searched using the Medical Subject Heading (MeSH) terms disasters, disaster medicine, rescue work, relief work, and conflict and then refined using the MeSH term developing country. The final list of selected manuscripts were analyzed by type of article, level of evidence, theme of the manuscript and topic, author affiliation, and region of the study. After searching and refining, developing countries. The majority was original research articles or reviews, and most of the original research articles were level IV or V evidence. Less than 25% of the authors were from the developing world. The predominant themes were missions, health care provision, and humanitarian aid during the acute phase of disasters in the developing world. Considering that 85% of disasters and 95% of disaster-related deaths occur in the developing world, the overwhelming number of casualties has contributed insignificantly to the world's peer-reviewed literature. Less than 1% of all disaster-related publications are about disasters in the developing world. This may be a publication bias, or it may be a genuine lack of submissions dealing with these disasters. Authors in this part of the world need to contribute to future disaster research through better-quality systematic research and better funding priorities. Aid for sustaining long-term disaster research may be a more useful investment in mitigating future disasters than short

  9. Present status and problems of development of fast breeder reactors

    International Nuclear Information System (INIS)

    Ikeda, Hiroshi

    1984-11-01

    The development of FBRs in Japan now reached the stage to conclude on the development organization for a demonstration reactor positioning one step before a practical reactor. FBRs can be operated while converting uranium-238 existing in natural uranium by 99.3% to fissile plutonium-239, as the result, the nuclear fuel more than that consumed can be produced. However, there are various technical difficulties in FBRs, and the construction cost is estimated to be considerably higher as compared with that of LWRs. Also the plutonium obtained by reprocessing spent fuel is used for FBRs, accordingly, the development of FBRs is inseparable from the establishment of nuclear fuel cycle. In order to get rid of the burden of enormous development cost for FBRs, the trend of international joint development is conspicuous. The Superphenix with 1200 MWe output under construction centering around SERENA is expected to attain the criticality in the spring of 1985. For the development of a demonstration reactor, it is necessary to increase the role of private businesses, and the smooth transfer of know-how accumulated in Power Reactor and Nuclear Fuel Development Corp. to civilian side is an important problem. (Kako, I.)

  10. Development of Artificial Antigen Presenting Cells for Prostate Cancer Immunotherapy

    National Research Council Canada - National Science Library

    Schneck, Jonathan P; Oelke, Mathias

    2007-01-01

    While adoptive immunotherapy holds promise as a treatment for cancer, development of adoptive immunotherapy has been impeded by the lack of a reproducible and economically viable method for generating...

  11. [Present situation and development of acupuncture and moxibustion in Singapore].

    Science.gov (United States)

    Meng, Xian-Jun; Zhu, An-Ning; Liao, Xiu-Lian; Ouyang, Qiang-Bo

    2013-10-01

    The development history, education, legislation, charge and institutes of acupuncture and moxibustion in Singapore are introduced in this article. Acupuncture and moxibustion has been developed in Singapore since 1840. Nowadays there are three universities that set up standard Chinese medicine courses and two acupuncture-moxibustion associations. Legislation of acupuncture and moxibustion is published in 2000. The acupuncture and moxibustion is applied for approximately 50 kinds of diseases. The acupuncture and moxibustion is at one's own expense in public or private institutions, but cheap or completely free in charity.

  12. Developing Skills for Effective Academic Presentations in EAP

    Science.gov (United States)

    Bankowski, Elizabeth

    2010-01-01

    This study focused on training students in skills essential to making oral presentations based on original and independent research work as part of their English for Academic Purposes (EAP) course. As a result of the training, students showed an increase in the successful use of research-related skills and a great improvement in their ability to…

  13. Filmless radiography - present possibilities and direction of future developing

    International Nuclear Information System (INIS)

    Wocial, A.; Wojciechowski, Z.A.; Rozenblicki, Z.

    2008-01-01

    The paper presents introduction for new filmless radiography like CR Computed Radiography and DR Digital Radiography direct and non direct. The main factors are considered, which determine classification to different type of radiography. For each technique authors describe advantages and disadvantages supporting by practice examples. Paper contains a lot of practical information about a most of existing radiographic equipment at the NDT market. (author)

  14. Developing Enterprise Skills through Peer-Assessed Pitch Presentations

    Science.gov (United States)

    Faherty, Anna

    2015-01-01

    Purpose: The purpose of this paper is to investigate the impact of using summative peer assessment to develop enterprise skills within higher education. Design/methodology/approach: An empirical investigation analysing students own perceptions of the peer assessment process to evaluate its impact. Findings: Participating students indicate that…

  15. Present state on research and development of underground disposal

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-12-01

    In September, 1996, Power Reactor and Nuclear Fuel Development Corp. (PNC) arranged her old research and development (R and D) results to issue as a shape of `Technical report on R and D of high level radioactive waste underground disposal`. On the other hand, Radioactive waste special party in Committee of Atomic Energy at that time evaluated that technical possibility for safety establishment of underground disposal in Japan was elucidated and showed future problems in the technical development. Therefore, PNC proceeded further R and D for the second arrangement under consideration of such comments. As a result, in investigation of geological environment condition, main points were laid at study on rear-field feature and its long-term stability. In development of disposal technique, main points were laid at elucidation of design requirements confirmable to the near-field evaluation, main points were laid at upgrading validity of evaluation model to analytically evaluate the near-field feature using data with high reliability. (G.K.)

  16. Collaborative development of a natural-looking smile: case presentation.

    Science.gov (United States)

    Fondriest, James; Roberts, Matt

    2009-01-01

    Sophisticated patients want their dental concerns treated without appearing as if they have been restored. This case presentation describes the planning and treatment steps for the recreation of an aesthetic smile. The patient had dento-facial asymmetries and an elevated occlusal risk of fracture due to bruxism. Lithium disilicate glass ceramic in a pressed version with stocked veneering porcelain was selected as an ideal restorative material for natural aesthetics and to fulfill the strength requirements for the maxillary anterior restorations.

  17. Development and Present Situation Analysis of Power Transformer State Maintenance

    Science.gov (United States)

    Lv, Sen; Li, Biao; Li, Huan

    2018-02-01

    The pivotal status of power transformer in the power system is one of the most important equipment. The safety and reliability of its operation is directly related to the safety and stability of power system. Based on the analysis of the present situation of power transformer state maintenance in home and abroad. The paper points out the deficiency of the current method and provides a theoretical basis for further research, which has a certain guiding significance.

  18. Past and Present Development of INA's Liberalisation and Privatisation

    International Nuclear Information System (INIS)

    Lesic, A.; Stimac, B.

    2001-01-01

    The paper deals with the historical development aspects of the Croatian oil and gas industry INA. It describes the period from the very start of oil and gas production to the data of establishment of the Croatian state and afterwards. Some important milestones and political and economic events that impacted the development of the Croatian oil industry are described and commented, including changes toward liberalisation and privatisation of the oil and gas sector. The paper emphasises the role of INA in the Croatian economy and proposes some solutions for the liberalisation process and privatisation of the company that could prevent undesirable effects of privatisation and protect the interests of Croatia in the energy sector which is one of the main sectors of economy having influence on other production and service sectors and their competitiveness.(author)

  19. Present status and prospects of nuclear power development in China

    International Nuclear Information System (INIS)

    Peng Shilu

    1987-01-01

    Energy resource is an essential prerequisite for realizing the strategic objectives of the national economic development in China. By the end of this century the objectives of the national economic development are as follows: the national annual gross value of industrial and agricultural output will be quadrupled as that in 1980; the annual average revenue per capita is expected to be 800-1000 U.S. dollars. For realizing these objectives, a significant discrepancy is anticipated between the energy demand and energy supplied. It is concluded, therefore, that the utilization of nuclear power should be regarded as one of the components constituting China's energy resources. From a longterm point of view, nuclear power will play an even more important role with each passing day. (author)

  20. Present status and prospects of nuclear power development in China

    International Nuclear Information System (INIS)

    Zhao Renkai

    1994-01-01

    The current status and the guiding principles of nuclear power in China are discussed. With the expansion of China's reform and opening to outside world policy, the national economy growth was increased very rapidly. For continuous, stable and fast development of national economy, the safe, clean and economic nuclear energy will play an even more important role. It is envisaged that by 2020 nuclear power will account for about 20%. 1 ref., 4 tabs

  1. Mass-measurements at GANIL recent results and present developments

    International Nuclear Information System (INIS)

    Mittig, W.

    1992-01-01

    A time of flight together with a magnetic rigidity measurement of fragmentation products was used to get masses of neutron rich nuclei of A = 20 to A = 50 region. Beams of 48 Ca and 64 Ni provided good yields of these nuclei. Results are presented and compared to model predictions. Recently the authors used the second cyclotron of GANIL to measure with high resolution the mass of fusion and deep inelastic reaction products. The method is described and results are shown. Finally extension of this field by the superconducting doublet of solenoids SISSI is described. The possibility of mass-measurements with an Isol+cyclotron device following the GANIL accelerator is discussed

  2. Engaging the Audience: Developing Presentation Skills in Science Students

    OpenAIRE

    Stuart, Ann E.

    2013-01-01

    This article describes a graduate class in presentation skills (“PClass”) as a model for how a class with similar objectives, expectations and culture might be mounted for undergraduates. The required class is given for students in neuroscience and physiology programs at the University of North Carolina at Chapel Hill; I describe the class in the years I led it, from 2003–2012. The class structure centered on peer rehearsal, critiquing of PowerPoint, and chalk talks by the students; video-rec...

  3. Present and Future Developments in Radiotherapy Treatment Units.

    Science.gov (United States)

    Boyer

    1995-04-01

    Technical advances in the design of medical accelerators are making possible the exploration of new treatment techniques. Technology currently available to the radiation oncologist allows the use of internal and dynamic wedges. Multileaf collimators can be used for static treatment ports, and dynamic field shaping and beam modulation using multileaf collimators has been shown to be feasible. Computer interfaces are necessary to transfer the complex treatment sequences that are possible with these devices. Such network interfaces also provide for more efficient conventional treatments. New machines such as X-band linear accelerators and advanced proton accelerators are being developed for applications such as boron neutron capture therapy and proton conformal therapy.

  4. Present state of computer-aided diagnosis (CAD) development

    International Nuclear Information System (INIS)

    Fujita, Hiroshi

    2007-01-01

    Topics of computer-aided detection (CAD) are reviewed. Commercially available, Food and Drug Administration (FDA)-approved CAD systems are for fields of breast cancer (mammography), chest (flat X-ray and CT imaging) and colon (polyp detection). In Japan, only mammography CAD is approved. Efficacy of CAD is controversial, for which reliable database is important, and its construction is under development in various medical fields. Digitalized image is now popularized, which conceivably leads to improve the cost-effectiveness of diagnosis with CAD. For incentive, approval for health insurance would be the case as seen in the increased CAD sale by R2 Technology Co., and MHLW actually assists facilities to introduce the reading-aid system of mammography by sharing a half of its cost. There are 2 big projects for CAD study supported by MECSST, which the author concerns. One is the development of diagnostic aid for the multi-dimensional medical images where the multi-organ, multi-disease CAD system is considered. The other involves the CAD in brain MRI, in breast US and in eyeground picture. It is not in so far future for patients and doctors to fully enjoy the benefit of CAD. (R.T.)

  5. Present status of HTGR research and development, 1995

    International Nuclear Information System (INIS)

    1996-02-01

    Based on the Long-term Program for Development and Utilization of Nuclear Energy which was revised in 1987, the Japan Atomic Energy Research Institute (JAERI) has carried out the Research and Development (R and D) on the High Temperature Gas-cooled Reactors (HTGRs) in Japan. The JAERI obtained the installation permit of the High Temperature Engineering Test Reactor (HTTR) from the Government in November 1990 and started the construction of the HTTR facility in the Oarai Research Establishment in March 1991. The HTTR is a test reactor with thermal output of 30MW and outlet coolant temperature of 850degC at the rated operation and 950degC at the high temperature test operation, using the pin-in-block type fuel, and has capability to demonstrate nuclear process heat utilization. The reactor pressure vessel and intermediate heat exchanger were installed in the reactor containment vessel in 1994, and reactor internals were also installed in the reactor pressure vessel in 1995. The first criticality will be attained in December 1997. This report describes the design outline and construction progress of the HTTR, R and D of fuel, materials and components for the HTGR and high temperature nuclear heat application, and innovative and basic researches for high temperature technologies at the HTTR. (J.P.N.)

  6. Present Situation and Future Development Trend of Smart Clothing

    Directory of Open Access Journals (Sweden)

    Ju Fengfan

    2017-09-01

    Full Text Available With the rapid development of science and technology, our daily clothes are changing quietly. Wearable smart clothing has gradually the leading role in the clothing market. This article first explains the concept of wearable intelligent clothing in china, and then I analyze the various types of wearable smart clothing that is currently facing problems, and summarized about the key points and future directions of wearable intelligent clothing design. From the beginning of 2013, smart watches, bracelets, glasses have entered the public vision, become a "trendsetter who sought the object", this year the industry was identified as "the first year of wearable equipment". In simple terms, a wearable device is a portable device that can be worn directly on the body, or integrated into the user's clothing or accessories. However, with the development of wireless sensor technology, kinds of wearable smart clothing gradually appeared in people's life, the smart clothing is made up of small chip, electronic components, power equipment, embedded into clothing, can achieve a specific function, in order to facilitate people's life.

  7. Vitamin D assays: past and present debates, difficulties, and developments.

    Science.gov (United States)

    Fraser, William D; Milan, Anna M

    2013-02-01

    Clinical interest in Vitamin D and its purported roles not only in calcium and bone metabolism but in several other medical conditions (diabetes, cardiovascular disease, multiple sclerosis, cancer, psychiatric disorders, neuro-muscular disease) has led to a surge in laboratory requests for 25 hydroxy vitamin D and 1,25 dihydroxy vitamin D measurement. Circulating 25 hydroxy vitamin D concentration is routinely used as the best indicator of vitamin D status, but measurement of other metabolites, especially the physiologically active 1,25 dihyroxy vitamin D, are of clinical value. Over the last 40 years the development of assays for vitamin D and its metabolites from early competitive binding assays through to immunoassay and liquid chromatography aligned to mass spectrometry have demonstrated various analytical challenges, the advantages and disadvantages of each method are constantly changing with new technological developments. Immunoassay remains the predominant mode of measurement for 25-hydroxy vitamin D although problems with equimolar recovery of the D2 and D3 metabolites remain an issue. Standardisation of all assays has been improved but not resolved with the currently available reference materials as evidenced by the international vitamin D external quality assurance scheme, DEQAS. The choice of method for each laboratory remains a balance mainly between turn around time, convenience, cost and the specificity and accuracy of the information obtained. With increasing discussion and clinical interest surrounding other vitamin D metabolites the vitamin D assay debate is set to continue.

  8. Present state of research and development of MHD power generation

    International Nuclear Information System (INIS)

    Ikeda, Shigeru

    1978-01-01

    MHD power generation can obtain electric energy directly from the heat energy of high speed plasma flow, and the power generating plant of 1 million kW can be realized by this method. When the MHD power generation method is combined before conventional thermal power generation method, the thermal efficiency can be raised to about 60% as compared with 38% in thermal power generation plants. The research and development of MHD power generation are in progress in USA and USSR. The research and development in Japan are in the second stage now after the first stage project for 10 years, and the Mark 7 generator with 100 kW electric output for 200 hr continuous operation is under construction. The MHD power generation is divided into three types according to the conductive fluids used, namely combustion type for thermal power generation, unequilibrated type and liquid metal type for nuclear power generation. The principle of MHD power generation and the constitution of the plant are explained. In Japan, the Mark 2 generator generated 1,180 kW for 1 min in 1971, and the Mark 3 generator generated 1.9 kW continuously for 110 hr in 1967. The MHD generator with superconducting magnet succeeded in 1969 to generate 25 kW for 6 min. The second stage project aimes at collecting design data and obtaining operational experience for the construction of 10 MW class pilot plant, and the Mark 7 and 8 generators are planned. (Kako, I.)

  9. REGIONAL DEVELOPMENT - PAST, PRESENT AND FUTURE IN ROMANIA

    Directory of Open Access Journals (Sweden)

    SIMONA BIRIESCU

    2011-01-01

    Full Text Available Romania's participation in the implementation of EU regional policy means, first opportunity to benefit from a system of values that can be found between economic efficiency, environmental protection,ensuring minimum standards of existence, the definition of a "European lifestyle, urban values, qualified human resources. Moreover, European integration and openness to the EU internal market and the challenge involves increasing competitiveness, which can negatively affect the process of building an economy, like Romania. In this context, structural instruments are the most important resource that Romania will have to face the challenges of change and integration. However, regional development policy can not solely be the key to overall development of a state, especially in terms of its actual effects on growth are difficult to assess. A critical dimension of this is represented on the nature of economic and quality of other public policies that form the core of economic policy mix of a state: the legal protection of property rights and market economy, taxation, antitrust, etc.

  10. Present status of developing petroleum-substituting energy (EC)

    Science.gov (United States)

    1993-03-01

    The EC has had approximately 50% of its total energy demand supplied by imports from the exterior of the Community. Hence, it is getting important to develop oil-substituting renewable energy as well as to curtail the emission of carbon dioxide. In consideration of these situations, the results of investigation on the energy policy of the European Community are described. The policy comprises three courses: European Energy Charter, formation of an open European Community energy market, and environmental conservation. Particularly, concerning the reduction of carbon dioxide emission, the EC Council has decided to introduce carbon dioxide taxation so as to suppress the carbon dioxide emission in the year 2000 to the 1990 level. The arrangement for its introduction, however, encountered with difficulties because of the opposition of various countries other than the European Community and the industrial world of the European Community. Legislation of the investment promotion law for energy saving and the construction of infrastructure footing and an information network are ineffective due to the sluggish fuel price and economic recession. A plurality of EC member countries are advancing a comprehensive activity within the framework of the joint programs of research, development, and demonstration set for the renewable energy policy ensuring energy supply and environmental harmonization.

  11. The MQC experiment on Rome: Present status and future developments

    International Nuclear Information System (INIS)

    Cosmelli, C.

    1998-01-01

    The study of phenomena related to the quantum behavior of macroscopic systems is subjected to new efforts both from theoretical and experimental point of view. The validity in fact of the description of macroscopic systems given by Quantum Mechanics is still under test, especially for what concerns the macrorealistic interpretation of the real world and the influence of dissipation on quantum systems. Many groups tried in the last few years to realize an experimental set-up to perform an MQC experiment; the intrinsic dissipation however limited the possibility to fulfill the experimental requirements. The technology for realizing high quality Josephson Junctions is now so advanced that in principle the tests proposed in the last ten years can hopefully performed with success. In the following we will present a short description of the basic principles for an MQC experiment, with special emphasis on the experiment planned by the Rome group. (author)

  12. Feed enzyme technology: present status and future developments.

    Science.gov (United States)

    Ravindran, Velmurugu; Son, Jang-Ho

    2011-05-01

    Exogenous enzymes are now well accepted as a class of feed additives in diet formulations for poultry and pigs to overcome the negative effects of anti-nutritional factors, and to improve digestion of dietary components and animal performance. An overview of the current status of feed enzyme technology, including the different type of enzymes and modes of action, is provided. Variable response to enzyme supplementation is an important reason limiting the widespread acceptance of feed enzymes. The major reasons contributing to these variable responses are discussed. Main features of the next generation of feed enzymes and the various trends that will drive the future use of enzymes are highlighted. The use of feed enzymes in poultry and pig feed formulations is expected to increase in the future and this will be driven by on-going changes in the world animal production. Aquaculture and ruminant industries are emerging markets for exogenous feed enzymes. The article presents some promising patents on feed enzyme technology.

  13. Present state and perspectives of spa tourism development in Serbia

    Directory of Open Access Journals (Sweden)

    Jovičić Dobrica

    2008-01-01

    Full Text Available Apart from very contaminated spatial areas, there are places with attractive and non-polluted environment, that are suitable for tourism and recreation. Such places are spa resorts, characterized by numerous and various natural elements having significant health and recreative functions (thermo-mineral springs, rare gases, favorable climatic conditions, rich vegetation, etc., which attract attention of ample tourist demand. Serbia is welknown as a 'country of spa resorts', because of a great number of thermo-mineral springs, long tradition and their significance for tourism economy. Official statistical service keeps records of tourist flows only at 30 spa resorts (approximately, having participation at 95% of the total tourist trade in Serbia's spas. The topic of this paper is devoted to estimation of the present state and perspectives of spa tourism in Serbia. Special attention is focused on: analysis of resources for spa tourism, discussion of key factors for tourist valorization of Serbia's spas, investigation of structural features of spa tourism, comparison of Serbia's experiences in domain of spa tourism with contemporary trends in certain spa resorts in other European countries, and, finally, defining the most important tasks for spa tourism improvement.

  14. Present status on world alternative energy developments to oil

    International Nuclear Information System (INIS)

    Reddington, J.

    1980-01-01

    The IEA was established about five years ago in the OECD immediately after the oil crisis, and 20 countries have participated in it. Progress was observed in the control of the expansion of energy demand. The energy utilization in IEA member countries became efficient due to the contribution of new technologies, and owing to the improvement of productivity, the growth of energy consumption was less than 1% despite the GDP grew at the yearly rate of 2.5%. The expansion of the utilization of natural gas and coal is promising, but the projects of nuclear power generation are behind schedule. The short term prospect in petroleum market is discussed, and the price of crude oil tends to be stabilized. ''The prospect of energy in the world by 2000'' will be published by the IEA in the latter half of 1980. The scale of the development of nuclear power generation was reduced because the prediction of the rate of power generation growth was changed from 5.2% to 3.1%. The effect of new energy technologies on future energy market has been studied by the support of 15 countries, and it was recommended to give financial aid to heat pumps, coal liquefaction and the efficient recovery of oil and natural gas. Also the techniques for operating existing facilities under strict environment and safety regulations have been studied. (Kako, I.)

  15. Present Status of HTGR Utilization System Development in Japan

    International Nuclear Information System (INIS)

    Miyamoto, Yoshiaki

    2000-01-01

    Efforts are to be continuously devoted to establish and upgrade HTGR technology in the world. Japan Atomic Energy Research Institute (JAERI) has conducted the R and D of HTGRs since the 1960's in Japan, focusing on mainly the construction of High Temperature engineering Test Reactor (HTTR) which is an HTGR with a maximum helium gas temperature of 950 o C at the reactor outlet and HTGR utilization systems. The HTTR achieved first criticality on November 10, 1998 and will restart from January in 2001. In the R and D program of HTGR utilization systems, JAERI has conducted hydrogen production systems with HTGR to demonstrate the applicability of nuclear heat for extensive energy demands besides the electric power generation. JAERI has developed a hydrogen production system by steam reforming process of natural gas using nuclear heat supplied from the HTTR. Prior to the demonstration test of HTTR hydrogen production system, a 1/30-scale out-of-pile test facility is under construction for safety review and detailed design of the system. The out-of-pile test facility will be started in 2001 and will be continued about 4 years. The hydrogen permeation and corrosion tests have been carried out since 1997. Check and review for the demonstration program in the HTTR hydrogen production system will be made in 2001. Then the HTTR hydrogen production system is scheduled to be constructed from 2003 and demonstratively operated from around 2006. In parallel with the R and D of the HTTR hydrogen production system, hydrogen production method by thermochemical water splitting, so-called IS process, has been studied in JAERI. The IS process is placed as one of future candidates of the heat utilization systems of the HTTR following the steam reforming system. Continuous and stoichiometric production of hydrogen and oxygen for 48 hours was successfully achieved with a laboratory-scale apparatus mainly made of glass. Following this achievement, the study has been continued with a larger

  16. Tourism of Krapinske Toplice Spa - present position and possibilities of Its development

    Directory of Open Access Journals (Sweden)

    Martina Jakovčić

    2003-01-01

    Full Text Available This paper presents present state of development of tourism in Krapinske Toplice Spa and possibilities of further development from the geographical point of view. Natural, socio-economical, cultural and historical components of the area are analysed. Special attention is given to development of health tourism and its impact on the development of other types of tourism. Paper explains the main reason of slower tourist development of Krapinske Toplice in comparison to other spas in the region.

  17. Pecha Kucha Style Powerpoint Presentation: An Innovative Call Approach to Developing Oral Presentation Skills of Tertiary Students

    Science.gov (United States)

    Murugaiah, Puvaneswary

    2016-01-01

    In computer-assisted language learning (CALL), technological tools are often used both as an end and as a means to an end (Levy & Stockwell, 2006). Microsoft PowerPoint is an example of the latter as it is commonly used in oral presentations in classrooms. However, many student presentations are often boring as students generally read from…

  18. Perspectives on the Present State and Future of Higher Education Faculty Development in Kazakhstan: Implications for National Human Resource Development

    Science.gov (United States)

    Seitova, Dinara

    2016-01-01

    The article aims at examining the present state of higher education faculty development in Kazakhstan in the context of multidimensional nationwide development reforms and exploring implications for the National Human Resource Development of the country. For the purpose of this research, theoretical human resource development (HRD) and…

  19. Development present situation analysis of nuclear power industry in China and South Korea

    International Nuclear Information System (INIS)

    Huang Gang

    2011-01-01

    This paper introduces the present state and primary development experiences of South Korean nuclear power industry and the present state of Chinese nuclear power industry development, and comparatively analyzes and researches the differences between China and South Korea in nuclear power industry. At last, we come up with some suggestions and ideas to refer the follow-up development of Chinese nuclear power industry. (author)

  20. Information Security: Past, Present and Future - Impact of Developments in Information Technology on Security

    OpenAIRE

    Overbeek, P.L.

    1991-01-01

    The development of information security is addressed in relation to the development of information technology. The leading question is: how has information security developed itself so far, and how should it progress to address tomorrow's security needs. An overwiew is given of the use of information technology in the past, present and expectations for the future. For each period, the security requirements and solutions are discussed, It is made clear that the developments in information tech...

  1. STEM professional development: What's going on from the presenters' and participants' perspectives?

    Science.gov (United States)

    Williams, Randi

    This study was designed to explore elementary STEM professional development viewed from the presenters' and participants' perspectives. Numerous committees and educational organizations recommend investing in STEM professional development at the local, state, and national level. This investment must begin with research that inquires how STEM professional development is structured and what is needed for teacher and student success. Since there is a recent STEM education push in schools, elementary teachers need effective professional development in order to gain the necessary content, skills, confidence, and pedagogy required for those changing demands. This qualitative study embraced. Yin's case study methodology by observing short-duration STEM professional development for elementary teachers within a large metropolitan school system and an educational professional development agency. The study discussed the analysis and findings in the context of Bandura's sources of efficacy and Desimone's critical features of professional development. Data were gathered form professional development observations, presenter interviews, and participant interviews. The research questions for this study included: (a) based on Desimone's (2009) framework for professional development, what does content focused, active learning, coherence, duration, and collective participation look like in initial STEM professional development for elementary teachers? (b) are Bandura's (1997) four sources of self- efficacy: mastery experiences, vicarious experiences, social persuasion, and affective states evidenced within the short duration professional development? and (c) how do these two frameworks align between presenter and participant thoughts and actions? This study uncovered additional sources of efficacy are present in short-duration STEM professional development. These found sources include coherence, content, and active learning delivered in a definitive order. The findings of this study

  2. A Prognostic Model for Development of Profound Shock among Children Presenting with Dengue Shock Syndrome.

    Directory of Open Access Journals (Sweden)

    Phung Khanh Lam

    Full Text Available To identify risk factors and develop a prediction model for the development of profound and recurrent shock amongst children presenting with dengue shock syndrome (DSS.We analyzed data from a prospective cohort of children with DSS recruited at the Paediatric Intensive Care Unit of the Hospital for Tropical Disease in Ho Chi Minh City, Vietnam. The primary endpoint was "profound DSS", defined as ≥2 recurrent shock episodes (for subjects presenting in compensated shock, or ≥1 recurrent shock episodes (for subjects presenting initially with decompensated/hypotensive shock, and/or requirement for inotropic support. Recurrent shock was evaluated as a secondary endpoint. Risk factors were pre-defined clinical and laboratory variables collected at the time of presentation with shock. Prognostic model development was based on logistic regression and compared to several alternative approaches.The analysis population included 1207 children of whom 222 (18% progressed to "profound DSS" and 433 (36% had recurrent shock. Independent risk factors for both endpoints included younger age, earlier presentation, higher pulse rate, higher temperature, higher haematocrit and, for females, worse hemodynamic status at presentation. The final prognostic model for "profound DSS" showed acceptable discrimination (AUC=0.69 for internal validation and calibration and is presented as a simple score-chart.Several risk factors for development of profound or recurrent shock among children presenting with DSS were identified. The score-chart derived from the prognostic models should improve triage and management of children presenting with DSS in dengue-endemic areas.

  3. Offshore Wind Jobs and Economic Development Impact: Four Regional Scenarios (Presentation)

    Energy Technology Data Exchange (ETDEWEB)

    Tegen, S.

    2014-11-01

    NREL's Jobs and Economic Development Impact (JEDI) Model for Offshore Wind, is a computer tool for studying the economic impacts of fixed-bottom offshore wind projects in the United States. This presentation provides the results of an analysis of four offshore wind development scenarios in the Southeast Atlantic, Great Lakes, Mid-Atlantic, and Gulf of Mexico regions.

  4. Developing Oral Presentation Competence in Professional Contexts: A Design-Based Collaborative Approach

    Science.gov (United States)

    Pathak, Anil; Le Vasan, Mani

    2015-01-01

    The need to develop oral presentation skills with reference to students' specialized professional contexts has been well-recognised. Attempts have also been made to develop collaboration between engineering faculty and language teaching professionals. In this paper, we describe an experiment where students were given an opportunity to demonstrate…

  5. Online Self-Presentation on Facebook and Self Development During the College Transition.

    Science.gov (United States)

    Yang, Chia-chen; Brown, B Bradford

    2016-02-01

    Self-presentation, a central element of young people's identity development, now extends from face-to-face contexts to social networking sites. Online self-presentation may change when youth transition to college, faced with the need to reclaim or redefine themselves in the new environment. Drawing on theories of self-presentation and self development, this study explores changes in youth's online self-presentation during their transition to a residential college. It also examines associations between online self-presentation and students' self-esteem and self-concept clarity. We surveyed 218 college freshmen (M age = 18.07; 64 % female, 79 % White) at the beginning and again at the end of their first semester. Freshmen's Facebook self-presentation became less restricted later in the semester. Broad, deep, positive, and authentic Facebook self-presentation was positively associated with perceived support from the audience, which contributed to higher self-esteem contemporaneously, though not longitudinally. Intentional Facebook self-presentation engaged students in self-reflection, which was related to lower self-concept clarity concurrently but higher self-esteem longitudinally. Findings clarified the paths from multifaceted online self-presentation to self development via interpersonal and intrapersonal processes during college transition.

  6. The development and effects of a presentation skill improvement program for medical school students.

    Science.gov (United States)

    Park, Kwi Hwa; Park, Ie Byung

    2011-12-01

    The purpose of this study was to develop and examine a program that was designed to improve the presentation skills of medical school students. The program was implemented in 2-day workshops for 36 third-grade medical students in 2009, using the following procedures in order: needs assessment; an initial group presentation and peer evaluation; an initial self-evaluation with video recording; viewing of a model presentation; a second presentation in a group and peer evaluation; and a second self-assessment. Two types of survey questionnaires were used: a self-evaluation checklist and a questionnaire on workshop satisfaction and confidence of presentation. Eighty-three percent of the students recognized the importance of presentation skills. There were significant differences in 3 factors of self-evaluation-constructing contents, utilizing audio-visual media, and delivery skills- but not with regard to understanding content. In the post workshop satisfaction survey, participants reported that the workshop was helpful in improving their own presentation skills. They also stated that presentation in a group, peer feedback, and video analysis of the recording were helpful. After the workshop, students claimed that their confidence scores in utilizing audio-visual media were the highest. Medical students realize the importance of presentation skills training and workshops in increasing presentation skills and improving confidence in presenting. Video analysis and feedback of each participant's presentation within the group was effective in upgrading the student's presentation skills.

  7. Ion-stimulated Gas Desorption Yields of Electropolished, Chemically Etched, and Coated (Au, Ag, Pd, TiZrV) Stainless Steel Vacuum Chambers and St707 Getter Strips Irradiated with 4.2 MeV/u lead ions

    CERN Document Server

    Mahner, E; Küchler, D; Malabaila, M; Taborelli, M

    2005-01-01

    The ion-induced desorption experiment, installed in the CERN Heavy Ion Accelerator LINAC 3, has been used to measure molecular desorption yields for 4.2 MeV/u lead ions impacting under grazing incidence on different accelerator-type vacuum chambers. Desorption yields for H2, CH4, CO, and CO2, which are of fundamental interest for future accelerator applications, are reported for different stainless steel surface treatments. In order to study the effect of the surface oxide layer on the gas desorption, gold-, silver-, palladium-, and getter-coated 316 LN stainless steel chambers and similarly prepared samples were tested for desorption at LINAC 3 and analysed for chemical composition by X-ray Photoemission Spectroscopy (XPS). The large effective desorption yield of 2 x 104 molecules/Pb53+ ion, previously measured for uncoated, vacuum fired stainless steel, was reduced after noble-metal coating by up to 2 orders of magnitude. In addition, pressure rise measurements, the effectiveness of beam scrubbing with le...

  8. Standardized methodological assessment of research presentations (SHARP): development of a new instrument.

    Science.gov (United States)

    Farrokhyar, Forough; Dath, Deepak; Amin, Nalin; Bhandari, Mohit; Kelly, Stephen; Kolkin, Ann; Gill Pottruff, Catherine; Reid, Susan

    2014-06-01

    There are currently no validated guidelines to assess the quality of the content and the delivery style of scientific podium surgical presentations. We have developed a simple, short, and reliable instrument to objectively assess the overall quality of scientific podium presentations. A simple and efficient rating instrument was developed to assess the scientific content and presentation style/skills of the surgical residents' presentations from 1996 to 2013. Absolute and consistency agreement for the different sections of the instrument was determined and assessed overtime, by stage of the project and study design. Intraclass correlation coefficients with 95% confidence intervals were calculated and reported using a mixed-effects model. Inter-rater reliability for both absolute and consistency agreement was substantial for total score and for each of the 3 sections of the instrument. The absolute agreement for the overall rating of the presentations was .87 (.63 to .98) and .78 (.50 to .95), and the consistency agreement was .90 (.70 to .99) and .87 (.67 to .97) for the 2012 and 2013 institutional research presentations, respectively. Rater agreement for evaluating project stage and different study designs varied from .70 to .81 and was consistent over the years. The consistency agreement in rating of the presentation was .77 for both faculty and resident raters. Standardized methodological assessment of research presentations (SHARP) instrument rates the scientific quality of the research and style of the delivered presentation. It is highly reliable in scoring the quality of the all study designs regardless of their stage. We recommend that researchers focus on presenting the key concepts and significant elements of their evidence using visually simple slides in a professionally engaging manner for effective delivery of their research and better communication with the audience. Copyright © 2014 Elsevier Inc. All rights reserved.

  9. Present trends in livestock development in Africa and the Middle East

    International Nuclear Information System (INIS)

    Qureshi, A.W.

    1986-01-01

    Salient features of the performance of the livestock sector in Africa and the Middle East are presented. Some of the main problems and issues are briefly discussed. All issues of current interest covering socio-economic and organizational problems, policy matters and technical aspects of livestock developments are briefly described. (author)

  10. Development and Analysis of a Swept Blade Aeroelastic Model for a Small Wind Turbine (Presentation)

    Energy Technology Data Exchange (ETDEWEB)

    Preus, R.; Damiani, R.; Lee, S.; Larwood, S.

    2014-06-01

    As part of the U.S. Department-of-Energy-funded Competitiveness Improvement Project, the National Renewable Energy Laboratory (NREL) developed new capabilities for aeroelastic modeling of precurved and preswept blades for small wind turbines. This presentation covers the quest for optimized rotors, computer-aided engineering tools, a case study, and summary of the results.

  11. Incidence and risk factors for developing infection in patients presenting with uninfected diabetic foot ulcers

    Science.gov (United States)

    Parker, Tony J.; Kinnear, Ewan M.; Derhy, Patrick H.; Alvarado, Ann M.; Huygens, Flavia

    2017-01-01

    Objective There is a paucity of research on patients presenting with uninfected diabetic foot ulcers (DFU) that go on to develop infection. We aimed to investigate the incidence and risk factors for developing infection in a large regional cohort of patients presenting with uninfected DFUs. Methods We performed a secondary analysis of data collected from a validated prospective state-wide clinical diabetic foot database in Queensland (Australia). Patients presenting for their first visit with an uninfected DFU to a Diabetic Foot Service in one of thirteen Queensland regions between January 2012 and December 2013 were included. Socio-demographic, medical history, foot disease history, DFU characteristics and treatment variables were captured at the first visit. Patients were followed until their DFU healed, or if their DFU did not heal for 12-months, to determine if they developed a foot infection in that period. Results Overall, 853 patients were included; mean(standard deviation) age 62.9(12.8) years, 68.0% male, 90.9% type 2 diabetes, 13.6% indigenous Australians. Foot infection developed in 342 patients for an overall incidence of 40.1%; 32.4% incidence in DFUs healed foot deformity (1.4 (1.0–2.0)), female gender (1.5 (1.1–2.1)) and years of age (0.98 (0.97–0.99)) (all pfoot deformity, younger age, female gender and DFUs that have not healed by 3 months after presentation. PMID:28545120

  12. Present status of transport code development based on Monte Carlo method

    International Nuclear Information System (INIS)

    Nakagawa, Masayuki

    1985-01-01

    The present status of development in Monte Carlo code is briefly reviewed. The main items are the followings; Application fields, Methods used in Monte Carlo code (geometry spectification, nuclear data, estimator and variance reduction technique) and unfinished works, Typical Monte Carlo codes and Merits of continuous energy Monte Carlo code. (author)

  13. Incidence, Prevalence, Diagnostic Delay, and Clinical Presentation of Female 46,XY Disorders of Sex Development

    DEFF Research Database (Denmark)

    Berglund, Agnethe; Johannsen, Trine H; Stochholm, Kirstine

    2016-01-01

    , prevalence, age at diagnosis, and clinical presentation at diagnosis in 46,XY females. DESIGN AND SETTING: A nationwide study covering all known females with a 46,XY karyotype in Denmark since 1960. The diagnosis of 46,XY disorder of sex development (DSD) was determined by medical record evaluation, data......CONTEXT: The prevalence of phenotypic females with a 46,XY karyotype is low, thus current knowledge about age and clinical presentation at diagnosis is sparse even for the most frequent conditions, androgen insensitivity syndrome (AIS), and gonadal dysgenesis. OBJECTIVE: To estimate incidence.......0-13.5; range, 0-34 y) in AIS and 17.0 years (95% confidence interval, 15.5-19.0; range, 0-28 y) in gonadal dysgenesis (P = .001). Clinical presentation was dependent on cause of DSD. CONCLUSIONS: The first estimate on prevalence of 46,XY females is 6.4 per 100 000 live born females. The presentation of AIS...

  14. Development Of A Mobile Robot As A Test Bed For Tele-Presentation

    Directory of Open Access Journals (Sweden)

    Diogenes Armando D. Pascua

    2016-01-01

    Full Text Available In this paper a human-sized tracked wheel robot with a large payload capacity for tele-presentation is presented. The robot is equipped with different sensors for obstacle avoidance and localization. A high definition web camera installed atop a pan and tilt assembly was in place as a remote environment feedback for users. An LCD monitor provides the visual display of the operator in the remote environment using the standard Skype teleconferencing software. Remote control was done via the internet through the free Teamviewer VNC remote desktop software. Moreover, this paper presents the design details, fabrication and evaluation of individual components. Core mobile robot movement and navigational controls were developed and tested. The effectiveness of the mobile robot as a test bed for tele-presentation were evaluated and analyzed by way of its real time response and time delay effects of the network.

  15. The Self-Presentation Motives for Physical Activity Questionnaire: Instrument Development and Preliminary Construct Validity Evidence.

    Science.gov (United States)

    Howle, Timothy C; Dimmock, James A; Whipp, Peter R; Jackson, Ben

    2015-06-01

    With the aim of advancing the literature on impression management in physical activity settings, we developed a theoretically derived 2 by 2 instrument that was designed to measure different types of context-specific self-presentation motives. Following item generation and expert review (Study 1), the instrument was completed by 206 group exercise class attendees (Study 2) and 463 high school physical education students (Study 3). Our analyses supported the intended factor structure (i.e., reflecting acquisitive-agentic, acquisitive-communal, protective-agentic, and protective-communal motives). We found some support for construct validity, and the self-presentation motives were associated with variables of theoretical and applied interest (e.g., impression motivation and construction, social anxiety, social and achievement goals, efficacy beliefs, engagement). Taken together, the results indicate that the Self-presentation Motives for Physical Activity Questionnaire (SMPAQ) may be useful for measuring various types of self-presentation motives in physical activity settings.

  16. Development of a Mobile Robot as a Test Bed for Tele-Presentation

    Directory of Open Access Journals (Sweden)

    Diogenes Armando D. Pascua

    2016-05-01

    Full Text Available In this paper a human-sized tracked wheel robot with a large payload capacity for tele-presentation is presented. The robot is equipped with different sensors for obstacle avoidance and localization. A high definition web camera installed atop a pan and tilt assembly was in place as a remote environment feedback for users. An LCD monitor provides the visual display of the operator in the remote environment using the standard Skype teleconferencing software. Remote control was done via the internet through the free Teamviewer VNC remote desktop software. Moreover, this paper presents the design details, fabrication and evaluation of individual components. Core mobile robot movement and navigational controls were developed and tested. The effectiveness of the mobile robot as a test bed for tele-presentation were evaluated and analyzed by way of its real time response and time delay effects of the network

  17. Development of ventricular assist devices in China: present status, opportunities and challenges.

    Science.gov (United States)

    Gu, Kaiyun; Chang, Yu; Gao, Bin; Wan, Feng; Loisance, Daniel; Zeng, Yi

    2014-08-01

    The growing number of heart failure patients and the scarcity of organ donors account for the huge need for the development of mechanical circulatory systems, including ventricular assist devices (VADs) and artificial hearts, in China. Several research programmes on blood pumps have been under way for the last three decades. However, unlike in other countries, the development of VADs has been extremely slow, and no system is currently approved and available for clinical application. There are many reasons for this situation. This article provides an overview of the present development of experimental and clinical research on VADs in China. In addition, the challenges for the clinical development of mechanical circulatory support in China are discussed. © The Author 2014. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. All rights reserved.

  18. Country report present status and need of human resource development in nuclear field in Vietnam

    Energy Technology Data Exchange (ETDEWEB)

    Ngo Qui Viet [Department of Organization and Scientific Human Resource Development, The Ministry of Science, Technology and Environment, Hanoi (Viet Nam); Vu Dang Ninh [Department of Administration and Personnel, The Vietnam Atomic Energy Commission, Hanoi (Viet Nam)

    2000-12-01

    Vietnam Atomic Energy Commission (VAEC) was officially established in 1976, and is a national research and development organization in the field of nuclear science and technology for peaceful purposes in Vietnam. Under the VAEC, there are three institutes and one center. Status of main facilities, such as TRIGA MARK II, neutron generator, electron accelerator MT-17, and irradiation facilities are outlined in the paper. At present, the VAEC has a total staff of about 540 persons. The number of staff appears adequate to fulfill the present task on application of isotopes and nuclear techniques. When Vietnam decides to develop nuclear power program, the demand for human resources will be significantly high. During the last five years, Vietnam has been developing and implementing a national regulatory program on Radiation Protection and Nuclear Safety. The Ministry of Science, Technology and Environment (MOSTE) have established independent Vietnam Radiation Protection and Nuclear Safety Authority (VRPA) in 1994. If the Vietnamese Government approves the proposed nuclear power program, human resources training should be a key point for all research and development directions at all revel of personnel. When looking back in the history of formation and development of nuclear science and technology in Vietnam, the international cooperation has played an extremely important role in promoting the program. The exchange of information and direct participation in concrete cooperation activities under the framework of the Forum are expected. (Tanaka, Y.)

  19. Country report present status and need of human resource development in nuclear field in Vietnam

    International Nuclear Information System (INIS)

    Ngo Qui Viet; Vu Dang Ninh

    2000-01-01

    Vietnam Atomic Energy Commission (VAEC) was officially established in 1976, and is a national research and development organization in the field of nuclear science and technology for peaceful purposes in Vietnam. Under the VAEC, there are three institutes and one center. Status of main facilities, such as TRIGA MARK II, neutron generator, electron accelerator MT-17, and irradiation facilities are outlined in the paper. At present, the VAEC has a total staff of about 540 persons. The number of staff appears adequate to fulfill the present task on application of isotopes and nuclear techniques. When Vietnam decides to develop nuclear power program, the demand for human resources will be significantly high. During the last five years, Vietnam has been developing and implementing a national regulatory program on Radiation Protection and Nuclear Safety. The Ministry of Science, Technology and Environment (MOSTE) have established independent Vietnam Radiation Protection and Nuclear Safety Authority (VRPA) in 1994. If the Vietnamese Government approves the proposed nuclear power program, human resources training should be a key point for all research and development directions at all revel of personnel. When looking back in the history of formation and development of nuclear science and technology in Vietnam, the international cooperation has played an extremely important role in promoting the program. The exchange of information and direct participation in concrete cooperation activities under the framework of the Forum are expected. (Tanaka, Y.)

  20. NOTCH4 gene polymorphisms as potential risk factors for brain arteriovenous malformation development and hemorrhagic presentation.

    Science.gov (United States)

    Delev, Daniel; Pavlova, Anna; Grote, Alexander; Boström, Azize; Höllig, Anke; Schramm, Johannes; Fimmers, Rolf; Oldenburg, Johannes; Simon, Matthias

    2017-05-01

    OBJECTIVE Arteriovenous malformations (AVMs) of the brain are a frequent and important cause of intracranial hemorrhage in young adults. Little is known about the molecular-genetic pathomechanisms underlying AVM development. Genes of the NOTCH family control the normal development of vessels and proper arteriovenous specification. Transgenic mice with constitutive expression of active NOTCH4 frequently develop AVMs. Here, the authors report a genetic association study investigating possible associations between NOTCH4 gene polymorphisms and formation and clinical presentation of AVMs. METHODS After PCR amplification and direct DNA sequencing or restriction digests, 10 single-nucleotide polymorphisms (SNPs) of the NOTCH4 gene were used for genotyping 153 AVM patients and 192 healthy controls (i.e., blood donors). Pertinent clinical data were available for 129 patients. Uni- and multivariate single-marker and explorative haplotype analyses were performed to identify potential genetic risk factors for AVM development and for hemorrhagic or epileptic presentation. RESULTS Eleven calculated haplotypes consisting of 3-4 SNPs (most of which were located in the epidermal growth factor-like domain of the NOTCH4 gene) were observed significantly more often among AVM patients than among controls. Univariate analysis indicated that rs443198_TT and rs915895_AA genotypes both were significantly associated with hemorrhage and that an rs1109771_GG genotype was associated with epilepsy. The association between rs443198_TT and AVM bleeding remained significant in the multivariate regression analysis. CONCLUSIONS The authors' results suggest NOTCH4 SNPs as possible genetic risk factors for the development and clinical presentation of AVMs and a role of NOTCH4 in the pathogenesis of this disease.

  1. DEVELOPING ESL/EFL LEARNERS’ PUBLIC SPEAKING SKILLS THROUGH PECHA KUCHA PRESENTATIONS

    Directory of Open Access Journals (Sweden)

    Romualdo A. Mabuan

    2017-12-01

    Full Text Available In the 21st century workplace, there has been an increasing demand for graduates to possess communicative competence particularly in speaking. Anchored on the 21st Century Learning Framework (Partnership for 21st Century Skills or P21, 2006 and the TPACK Framework (Koehler & Mishra, 2009, this study reports findings on the pedagogical viability of utilizing Pecha Kucha 20x20 Presentations in developing students’ competence and confidence while presenting in the language classroom. Research participants include 43 English as Second Language (ESL learners taking Speech Communication classes in a private university in Manila, the Philippines during the second semester of the academic year 2016-2017. Research data from students’ reflections, interviews, survey, and focus group discussion (FGD suggest that despite some format and technological limitations, delivering Pecha Kucha presentations may help students develop their English speaking and oral presentation skills, build their confidence in speaking before an audience, and practice their English macro skills such as listening and reading. In the light of these findings, pedagogical implications are provided for ESL (English as a second language and EFL (English as a foreign language teachers, communication educators, and researchers.

  2. Development of guidelines for giving community presentations about eating disorders: a Delphi study.

    Science.gov (United States)

    Doley, Joanna Rachel; Hart, Laura Merilyn; Stukas, Arthur Anthony; Morgan, Amy Joanna; Rowlands, Danielle Lisa; Paxton, Susan Jessica

    2017-01-01

    Concerns exist around how to talk about eating disorders (EDs) due to evidence that suggests discussing ED symptoms and behaviours may cause or worsen symptoms in vulnerable people. Using expert consensus, we developed a set of guidelines for giving safe community presentations about EDs. Participants with professional ED expertise, and people with lived experience of an ED, were recruited for a Delphi study. N  = 26 panel members rated 367 statements for both a) inclusion in guidelines, and b) their potential to be helpful (increase knowledge, reduce stigma) or harmful (increase stigma, cause/worsen ED symptoms). After each round of the study, statements were classified as endorsed, re-rate, or not endorsed. 208 statements were endorsed by the panel over three rounds. 13 statements were strongly endorsed in the first round, with both people with lived experience and professionals agreeing it is important for presentations to include information on etiology of EDs and to promote help-seeking. Several statements had a high level of disagreement between those with lived experience and professionals, including the idea that presentations should suggest dieting is likely to result in weight gain. The experts were able to develop consensus on a wide range of issues. Panel members, particularly people with lived experience, were sensitive to aspects of presentations that may be harmful to an audience. The guidelines fill an important gap in the literature and provide guidance to those educating the public about EDs; they should, however, be further evaluated to test their efficacy.

  3. Present status and future challenges of nuclear forensics technology developments in JAEA

    International Nuclear Information System (INIS)

    Kimura, Yoshiki; Shinohara, Nobuo; Okubo, Ayako; Toda, Nobufumi; Funatake, Yoshio; Kataoka, Osamu; Matsumoto, Tetsuya; Watahiki, Masaru; Kuno, Yusuke

    2014-01-01

    Japan Atomic Energy Agency (JAEA) has started a nuclear forensics (NF) technology development project from JFY 2011, according to the National Statement of Japan in Nuclear Security Summit 2010. This paper will present the progress and future prospects of the development project during JFY 2011 to 2013. The project on NF technology in JAEA includes the development of analytical technologies such as isotope and impurity measurements, morphology analysis, age determination technique, and the prototype of nuclear forensics library (NFL) for future national NFL. Some analytical devices were installed for the analytical technology developments, and various uranium materials produced in JAEA facilities at Ningyo-toge have been measured to verify the analytical technologies. A nuclear material database of the prototype NFL was also developed with brief tools of multivariate analysis and image analysis. The implementation of the analytical technologies, the development of advanced analytical technologies and the system improvements of the prototype NFL will be continued from JFY 2014 in JAEA. The national regime and national response plan are remained as a big challenge to establish the national NF capabilities in Japan. (author)

  4. Fuji electric's past and present efforts in the development of nuclear energy

    International Nuclear Information System (INIS)

    Hayakawa, Hitoshi; Miki, Toshiya; Okamoto, Futoshi

    2003-01-01

    Since the inception of Japan's national nuclear energy program, Fuji Electric has built experimental facilities for various types of nuclear reactors, constructed Japan's first commercial nuclear power plant, and has continued to contribute to the development of national nuclear energy. This paper presents an overview of the specific features of Fuji Electric's technology and efforts in nuclear energy development. Fuji Electric's proprietary technologies include gas-cooled reactor technology, remote-handling and mechatronics technology, rad-waste treatment technology, and superconductivity technology. Through the application of these technologies, Fuji Electric plays a major role in the development of advanced reactors such as high temperature gas-cooled reactors and fast breeder reactors, and in the fields of MOX fuel fabrication, nuclear plant decommissioning, radwaste treatment systems and fusion energy. (author)

  5. Present status of development of alternative energy technology from environment protection point of view

    International Nuclear Information System (INIS)

    Tanaka, T.

    1992-01-01

    This paper reports that Japan lacks fossil fuel resources. Consequently, almost all fossil fuels are imported from abroad. Therefore, change in international affairs affects on Japan's politics and social life, as learned from experience of economic social life, as learned from experience of economic confusion caused by the oil crisis of 1973. For this reason, research and development (R and D) of alternative energy technologies was initiated in July 1974, which was promoted as one of national energy development programs called Sunshine Project. Presently, their technical developments are being continued to put practical use under this project. However, Japan's dependency of primary energy resources on oil is still high among major advanced countries and energy supply structure is significantly weak. Furthermore, from indetermination of the recent political condition in the Middle East, the importance of security against supply and demand of petroleum in middle and long term is generally recognized with the increasing cost of oil

  6. Present status and potential of group contribution methods for process development

    Energy Technology Data Exchange (ETDEWEB)

    Gmehling, Juergen [Lehrstuhl fuer Technische Chemie, Carl von Ossietzky Universitaet Oldenburg, D-26121 Oldenburg (Germany)

    2009-06-15

    The development of chemical processes can be performed with the help process simulators. However, for the simulation, besides kinetic data, a reliable knowledge of the pure component and mixture properties is required. Since often 60-80% of the total costs arise in the separation step, a reliable knowledge of the phase equilibrium behaviour of the system to be separated is of special importance. The models for excess Gibbs energy g{sup E} and equations of state allow the calculation of the phase equilibrium behaviour of multicomponent systems using binary information alone. But often, the required binary experimental data are missing. For these systems, a reliable predictive thermodynamic model with a large range of applicabilities would be most desirable. With a view to the development of a powerful predictive method, work on the development of a group contribution method was started in Dortmund 1973. A prerequisite for this work is a large database. Therefore, all published pure component properties, phase equilibrium data, and excess properties were stored in a computerized form. At the same time, experimental techniques for the systematic measurements were built up to measure the missing values. The information stored was used for the development of the group contribution method UNIFAC. The weaknesses of this method were removed with the development of modified UNIFAC. With the introduction of g{sup E}-mixing rules in equations of state, the usage of the 'solution of groups'-concept lead to group contribution equations of state. In combination with electrolyte models, the influence of strong electrolytes on the phase equilibrium behaviour can be taken into account. In this paper, the continuous development, present status, and potential of group contribution methods for the development of chemical processes will be shown.

  7. Developing a multidisciplinary approach within the ED towards domestic violence presentations.

    Science.gov (United States)

    Basu, Subhashis; Ratcliffe, Giles

    2014-03-01

    To improve the detection and quality of care of patients who attend the emergency department (ED) with confirmed or suspected domestic abuse (DA). A quality improvement report on the design, implementation and evaluation of a specialised service and structured training programme to detect and manage DA presentations within an emergency medicine department. The study was set in the ED at the Northern General Hospital, Sheffield, UK. Key measures for improvement included introducing a service within the ED to help staff manage DA and coordinate responses; improve staff confidence in detecting DA; develop a structured and consistent process by which to manage DA presentations. An Independent Domestic Violence Advocate service was introduced into the department in July 2011 through a multiagency agreement. A structured training and education programme was delivered to ED staff. A 'communications form' was developed for DA risk assessment and case management. The process was reviewed quarterly. One hundred and seventy-two referrals were made to the service (121 distinct clients) over a 12-month period. Staff reported greater confidence in detecting DA, and community partners highlighted the role the service had in improving DA detection and care quality within the city. Strong leadership and prioritising the issue within the department has facilitated the development of the process and contributed substantially to its success. Support from community partners has been invaluable in tailoring the service and education programme to the needs of staff and patients within the department.

  8. Present status of the {sup 129}Xe comagnetometer development for neutron EDM measurement

    Energy Technology Data Exchange (ETDEWEB)

    Mihara, M., E-mail: mihara@vg.phys.sci.osaka-u.ac.jp [Osaka University, Department of Physics (Japan); Masuda, Y. [Institute of Particle and Nuclear Studies (IPNS), High Energy Accelerator Research Organization (KEK) (Japan); Matsuta, K. [Osaka University, Department of Physics (Japan); Kawasaki, S.; Watanabe, Y. [Institute of Particle and Nuclear Studies (IPNS), High Energy Accelerator Research Organization (KEK) (Japan); Hatanaka, K.; Matsumiya, R. [Osaka University, Research Center for Nuclear Physics (RCNP) (Japan)

    2016-12-15

    A {sup 129}Xe comagnetometer designed for the measurement of neutron electric dipole moment (nEDM) as precisely as 1 × 10{sup −27}e cm is presented. Highly nuclear spin polarized {sup 129}Xe are introduced into an EDM cell where the {sup 129}Xe spin precession is detected by means of the two-photon transition. The geometric phase effect (GPE) which generates the false nEDM was quantitatively discussed and the systematic error of nEDM from the GPE was estimated considering the buffer-gas suppression due to Xe atomic collisions. Research and development are in progress to construct the {sup 129}Xe comagnetometer with a field sensitivity of 0.3 fT. At present, about 70 % nuclear spin polarized {sup 129}Xe atoms have been obtained in a spin exchange opitial pumping cell, that are in the process of being transferred into the EDM cell via a cold trap.

  9. Long term needs for nuclear data development. Texts of papers presented at the advisory group meeting

    International Nuclear Information System (INIS)

    Herman, M.

    2001-08-01

    This report contains the texts of the invited presentations delivered at the Advisory Group Meeting on Long Term Needs for Nuclear Data Development. The meeting was organized by the International Atomic Energy Agency (IAEA) and held at IAEA Headquarters, Vienna, Austria, 28 November - 1 December 2000. The texts are reproduced here, directly from the author's manuscripts with little or no editing, in the order in which the presentations were made at the meeting. For the main conclusions refer to the Summary Report, published as INDC(NDS)-423. The contributed papers deal with cross section data needed for production of radionuclides; for internal radiation dosimetry; for ion beam analysis; neutron data needs in astrophysics; nuclear data for advanced fast reactors; lead cooled reactors; accelerator driven subcritical assemblies

  10. Present status and future development of the European Community rapid information system

    International Nuclear Information System (INIS)

    Fraser, G.

    1990-01-01

    Following the Chernobyl reactor accident it was rapidly appreciated that, in addition to upgrading national radiological monitoring systems, action was required to facilitate international communication of the results obtained. The first such system was established by the Vienna Convention, drawn up under the auspices of the IAEA, which came into force in September, 1986. Subsequently the EC Council of Ministers decided in December, 1987, to set up a Community system which in many ways parallels that established by the Convention but differs significantly in certain aspects concerning its legal basis, initiation criteria, data provisions and communications requirements. The present paper describes the present status of the Community system and foreseeable future developments. It is a matter of policy that, to avoid unnecessary complications, this system should be, to the maximum extent practicable, fully compatible with that established by the Convention. Where appropriate, therefore, reference is also made to the latter system

  11. Accelerating Development of EV Batteries Through Computer-Aided Engineering (Presentation)

    Energy Technology Data Exchange (ETDEWEB)

    Pesaran, A.; Kim, G. H.; Smith, K.; Santhanagopalan, S.

    2012-12-01

    The Department of Energy's Vehicle Technology Program has launched the Computer-Aided Engineering for Automotive Batteries (CAEBAT) project to work with national labs, industry and software venders to develop sophisticated software. As coordinator, NREL has teamed with a number of companies to help improve and accelerate battery design and production. This presentation provides an overview of CAEBAT, including its predictive computer simulation of Li-ion batteries known as the Multi-Scale Multi-Dimensional (MSMD) model framework. MSMD's modular, flexible architecture connects the physics of battery charge/discharge processes, thermal control, safety and reliability in a computationally efficient manner. This allows independent development of submodels at the cell and pack levels.

  12. Present status of spallation target development. JAERI/KEK Joint Project

    International Nuclear Information System (INIS)

    Hino, R.; Kaminaga, M.; Haga, K.

    2001-01-01

    The Japan Atomic Energy Research Institute (JAERI) and the High Energy Accelerator Research Organization (KEK) are promoting a plan to construct a neutron scattering facility under the JAERI/KEK Joint Project. Design and R and D works are being carried out vigorously for realizing the mercury target system consisting of the mercury target, moderators and reflectors working as a spallation neutron source, as well as a remote handling system for exchanging such components which will be highly irradiated. This report introduces an outline of the present status of design and development activities on the spallation target system. (author)

  13. [The theory of mechanical activity of lungs--a creation history, the present and development prospects].

    Science.gov (United States)

    Tetenev, F F; Tetenev, K F

    2014-01-01

    In article the history of creation of the doctrine about respiratory movements of lungs, history of classical mechanics of breathing is stated. Supervision of the paradoxical facts which became a basis for hypothesis creation, then the theory of mechanical activity of lungs are presented. The facts proving mechanical activity of lungs on an inspiration and an expiration are given. Options of interaction of intra pulmonary and extra pulmonary sources of mechanical energy are considered. Theoretical justification for development of the new direction of studying of physiology of mechanical movements of the internal which does not have own skeleton is stated.

  14. The development of the k{sub 0} method in Peru: Past, present and future perspectives

    Energy Technology Data Exchange (ETDEWEB)

    Montoya, E., E-mail: emontoya@ipen.gob.p [Instituto Peruano de Energia Nuclear, Av. Canada 1470, Lima 41 (Peru); Bedregal, P.; Mendoza, P.; Ubillus, M.; Torres, B. [Instituto Peruano de Energia Nuclear, Av. Canada 1470, Lima 41 (Peru); Cohen, I.M. [Universidad Tecnologica Nacional, Facultad Regional Avellaneda, Secretaria de Ciencia, Tecnologia e Innovacion Productiva, Av. Mitre 750 (1870) Avellaneda (Argentina)

    2010-10-11

    The k{sub 0} method was implemented at the Peruvian Institute of Nuclear Energy (IPEN), by 1993. Since the middle of 1994, almost all INAA work at IPEN is performed by the k{sub 0} method. The establishment, applications, development and future of the method in Peru are presented from a retrospective and prospective view. Attention is paid to difficult aspects, e.g. counting efficiency, characterization of irradiation facility; non-ideal behaviour of the epithermal neutron spectrum and consistency of nuclear input data.

  15. Research and development of energy harvesting from vibrations and human motions (Conference Presentation)

    Science.gov (United States)

    Liao, Wei-Hsin

    2017-04-01

    Most of the ambient energy, which was regarded useless in the past, now is under the spotlight. With the rapid developments on low power electronics, future personal mobile devices and remote sensing systems might become self-powered by scavenging energy in different forms from their surroundings. Kinetic energy is one of the promising energy forms in our living environment, e.g., human motions and vibrations. We have proposed an energy flow to clarify the functions of piezoelectric energy harvesting, dissipation, and their effects on the structural damping of vibrating structures. Impedance modeling and analysis were performed. We have designed an improved self-powered switching interface for piezoelectric energy harvesting circuits. With electromagnetic transduction, we also proposed a knee-mounted energy harvester that could convert the mechanical power from knee joints into electricity during walking. On the other hand, we have developed magnetorheological (MR) fluid devices with multiple functions, including rotary actuators and linear dampers. Multifunctional rotary actuator was designed to integrate motor/generator part and MR fluids into a single device. The actuator could function as motor, generator, clutch and brake, with compact size and good energy efficiency. In addition, novel self-sensing MR dampers with power generation, so as to integrate the dynamic sensing, controllable damping and power generation functions, were developed and investigated. Prototypes were fabricated and tested. The developed actuators were promising for various applications. In this paper, related research in energy harvesting done at The Chinese University of Hong Kong and key results will be presented.

  16. Nuclear power in the world. Its present status and development trends

    International Nuclear Information System (INIS)

    Bennett, L.

    1994-01-01

    A summary of the most important data about the nuclear power reactors in operation and under construction as of the end of 1993 is given: their capacity, share of world capacity, growth of nuclear electricity generation since 1970 and its distribution by country. Nuclear prospects in the medium (2015) and long term (2025) are connected with a broad range of factors: development of advanced reactors ensuring high level of safety, implementation of high level waste repositories, enhancing the public acceptance of nuclear power. The issue of the cost of electricity generation is also discussed. Nuclear capacity projections to 2015 by region are given with 'low' and 'high' estimates. The low case reflects the continuation of the present trend of stagnation in nuclear power development due to public opposition and low economic growth in OECD countries, uncertainties in Eastern Europe and lack of finding in developing countries. The high case reflects a moderate revival of nuclear power development in the light of a more comprehensive assessment of the macro-economic and environmental aspects of the different options available for electricity generation. 7 figs., 5 tabs. (R.T.)

  17. Statistical learning in typically developing children: the role of age and speed of stimulus presentation.

    Science.gov (United States)

    Arciuli, Joanne; Simpson, Ian C

    2011-05-01

    It is possible that statistical learning (SL) plays a role in almost every mental activity. Indeed, research on SL has grown rapidly over recent decades in an effort to better understand perception and cognition. Yet, there remain gaps in our understanding of how SL operates, in particular with regard to its (im)mutability. Here, we investigated whether participant-related variables (such as age) and task-related variables (such as speed of stimulus presentation) affect visual statistical learning (VSL) in typically developing children. We tested 183 participants ranging in age from 5 to 12 years and compared three speeds of presentation (using stimulus durations of 800, 400 and 200 msecs). A multiple regression analysis revealed significant effects of both age and speed of presentation - after attention during familiarization and gender had been taken into consideration. VSL followed a developmental trajectory whereby learning increased with age. The amount of learning increased with longer presentation times (as shown by Turk-Browne, Jungé & Scholl, 2005, in their study of adults). There was no significant interaction between the two variables. These findings assist in elucidating the nature of statistical learning itself. While statistical learning can be observed in very young children and at remarkably fast presentation times, participant- and task-related variables do impact upon this type of learning. The findings reported here may serve to enhance our understanding of individual differences in the cognitive and perceptual processes that are thought to rely, at least in part, on SL (e.g. language processing and object recognition).

  18. The past, present, and future of health development campaigns: reflexivity and the critical-cultural approach.

    Science.gov (United States)

    Dutta, Mohan Jyoti; de Souza, Rebecca

    2008-07-01

    In contemporary society, health issues have gained increasing urgency in both political and academic spheres. Looking back at the failure of the modernist development initiatives, there is the need to realize that we live in a time of increasing sociopolitical complexity. The present moment is perhaps best understood in terms of a complex tension and linkage between the past and present, global and local, modern and postmodern. The critical-cultural approach to health campaigns is an approach that, through the reflexive interrogation of modernist assumptions underlying health communication campaigns, attempts to foreground the tensions inherent in the practice of health campaigns. This essay discusses the manner in which the critical-cultural approach interrogates modernist assumptions and provides an alternative paradigm for approaching the theory and practice of health campaigns by suggesting the necessity for reflexivity. Specifically, we discuss how the perspective interrogates the role of the media in development, the significance of culture, the locus of health responsibility, the impact of structural conditions, and the politics of knowledge, providing examples of campaigns that illustrate this reflexivity.

  19. Development and Presentation of the Drigg Post-Closure Safety Case

    International Nuclear Information System (INIS)

    Kelly, Eugene; Watts, Len; Grimwood, Paul

    2001-01-01

    Drigg is an operational facility for the near-surface disposal of solid low level radioactive waste (LLW). The disposal facility is located in Cumbria, north-west England, near the Sellafield nuclear site, and is owned and operated by British Nuclear Fuels plc (BNFL). Disposals at Drigg are carried out under the terms of an authorisation granted by the UK Environment Agency. Periodically the Drigg authorisation is subject to formal regulatory review. The current regulatory guidance, 'Disposal Facilities on Land for Low and Intermediate Level Radioactive Wastes: Guidance on Requirements for Authorisation' (the GRA) was published in 1997 and contains guidance on the principles and requirements against which the Environment Agency will consider applications for disposal authorisation. BNFL has undertaken to produce an updated Drigg postclosure safety case (PCSC) in September 2002 to support the next authorisation review. In preparation for this, BNFL published a 'Status Report on the Development of the 2002 Drigg PCSC' in March 2000. This paper discusses the main components of the Drigg PCSC and how they relate to each other. Central to the safety case will be a systematic, post-closure radiological safety assessment (PCRSA). However the main focus of this paper is on the other main components of the PCSC which are presented in conjunction with the PCRSA to make a complete and integrated safety case. In addition other confidence building activities which are key to developing and presenting the safety case are discussed, in particular communications with the stakeholders

  20. Tales from the Dark Side: Teacher Professional Development , Support , Activities, Student Research & Presentations

    Science.gov (United States)

    Walker, C. E.; Pompea, S. M.

    2013-12-01

    In a partnership last Spring with Arizona Public Service, the National Optical Astronomy Observatory (NOAO) created the 'Dark-Skies Energy Education Program: Energy Awareness for a Sustainable Future'. In this program, experienced science and technology education specialists from NOAO led 2 one-day professional development workshops for thirteen 6th grade teachers on dark skies and energy education. The workshops focused on three foundational, scaffolding activities and a final student research project. This in turn culminated in a Family Science Night where students presented their projects. In between these events, our NOAO team provided support for teachers through real-time video conferencing using FaceTime. In addition to the professional development, each teacher received a kit full of resource materials to perform the activities and research project. The kit was at no cost to the teacher, school, or district. Each kit contained the latest version of a tablet, which was used to facilitate communication and support for the teachers, as well as provide all the program's written teaching materials. The activities are in accordance with state, Common Core and Next Generation Science Standards. Our NOAO instructors gave firsthand experiences on how best to use these materials in a classroom or public setting. They also discussed opportunities on how they can incorporate, adapt and expand upon the activities and research projects in the classroom. Evaluation reports from the program's independent evaluator showed that the students enjoyed learning from the three foundational activities and research projects. The project presentations by the Yuma students were outstanding in their creativity, level of effort, and scientific accuracy. To summarize the evaluations, significant changes in knowledge and attitude were made with the teachers and students (from one-on-one interviews and surveys), but behavioral changes (albeit only over a semester) seemed minimal. The AGU

  1. Development of ultrashort x-ray/gamma-ray sources using ultrahigh power lasers (Conference Presentation)

    Science.gov (United States)

    Kim, Hyung Taek; Nakajima, Kazuhisa; Hojbota, Calin; Jeon, Jong Ho; Rhee, Yong-Joo; Lee, Kyung Hwan; Lee, Seong Ku; Sung, Jae Hee; Lee, Hwang Woon; Pathak, Vishwa B.; Pae, Ki Hong; Sebban, Stéphane; Tissandier, Fabien; Gautier, Julien; Ta Phuoc, Kim; Malka, Victor; Nam, Chang Hee

    2017-05-01

    Short-pulse x-ray/gamma-ray sources have become indispensable light sources for investigating material science, bio technology, and photo-nuclear physics. In past decades, rapid advancement of high intensity laser technology led extensive progresses in the field of radiation sources based on laser-plasma interactions - x-ray lasers, betatron radiation and Compton gamma-rays. Ever since the installation of a 100-TW laser in 2006, we have pursued the development of ultrashort x-ray/gamma-ray radiations, such as x-ray lasers, relativistic high-order harmonics, betatron radiation and all-optical Compton gamma-rays. With the construction of two PW Ti:Sapphire laser beamlines having peak powers of 1.0 PW and 1.5 PW in 2010 and 2012, respectively [1], we have investigated the generation of multi-GeV electron beams [2] and MeV betatron radiations. We plan to carry out the Compton backscattering to generate MeV gamma-rays from the interaction of a GeV electron beam and a PW laser beam. Here, we present the recent progress in the development of ultrashort x-ray/gamma-ray radiation sources based on laser plasma interactions and the plan for developing Compton gamma-ray sources driven by the PW lasers. In addition, we will present the applications of laser-plasma x-ray lasers to x-ray holography and coherent diffraction imaging. [references] 1. J. H. Sung, S. K. Lee, T. J. Yu, T. M. Jeong, and J. Lee, Opt. Lett. 35, 3021 (2010). 2. H. T. Kim, K. H. Pae, H. J. Cha, I J. Kim, T. J. Yu, J. H. Sung, S. K. Lee, T. M. Jeong, J. Lee, Phys. Rev. Lett. 111, 165002 (2013).

  2. Uncooled Terahertz real-time imaging 2D arrays developed at LETI: present status and perspectives

    Science.gov (United States)

    Simoens, François; Meilhan, Jérôme; Dussopt, Laurent; Nicolas, Jean-Alain; Monnier, Nicolas; Sicard, Gilles; Siligaris, Alexandre; Hiberty, Bruno

    2017-05-01

    As for other imaging sensor markets, whatever is the technology, the commercial spread of terahertz (THz) cameras has to fulfil simultaneously the criteria of high sensitivity and low cost and SWAP (size, weight and power). Monolithic silicon-based 2D sensors integrated in uncooled THz real-time cameras are good candidates to meet these requirements. Over the past decade, LETI has been studying and developing such arrays with two complimentary technological approaches, i.e. antenna-coupled silicon bolometers and CMOS Field Effect Transistors (FET), both being compatible to standard silicon microelectronics processes. LETI has leveraged its know-how in thermal infrared bolometer sensors in developing a proprietary architecture for THz sensing. High technological maturity has been achieved as illustrated by the demonstration of fast scanning of large field of view and the recent birth of a commercial camera. In the FET-based THz field, recent works have been focused on innovative CMOS read-out-integrated circuit designs. The studied architectures take advantage of the large pixel pitch to enhance the flexibility and the sensitivity: an embedded in-pixel configurable signal processing chain dramatically reduces the noise. Video sequences at 100 frames per second using our 31x31 pixels 2D Focal Plane Arrays (FPA) have been achieved. The authors describe the present status of these developments and perspectives of performance evolutions are discussed. Several experimental imaging tests are also presented in order to illustrate the capabilities of these arrays to address industrial applications such as non-destructive testing (NDT), security or quality control of food.

  3. A review on past and present development on the interlocking loadbearing hollow block (ILHB) system

    Science.gov (United States)

    Bosro, M. Z. M.; Samad, A. A. A.; Mohamad, N.; Goh, W. I.; Tambichik, M. A.; Iman, M. A.

    2018-04-01

    Massive migration and increasing population in Malaysia has contributed to the increasing demand of quality and affordable housing. Over the past 50 years, the Malaysian housing industry has seen the growth of using conventional construction system such as reinforced concrete frame structures and bricks. The conventional system, as agreed by many researchers, causes delays and other disadvantages in some of the construction projects. Thus, the utilization of interlocking loadbearing hollow block (ILHB) system is needed to address these issues. This system has been identified as an alternative and sustainable building system for the construction industry in Malaysia which the PUTRA block system is the latest example of the ILHB developed. The system offers various advantages in terms of speed and cost in construction, strength, environmentally friendly and aesthetic qualities. Despite these advantages, this system has not been practically applied and develop in Malaysia. Therefore, this paper aims to review the past and present development of the interlocking loadbearing hollow block (ILHB) system that available locally and globally.

  4. Women’s Participation in Africa’s Nuclear Development-Challenges and Opportunities (Poster Presentation)

    International Nuclear Information System (INIS)

    Mkhosi-Motsaathebe, M.

    2015-01-01

    Expansion of nuclear technologies and plans for new plants in Africa makes this an exciting time for more women to be involved in the nuclear sector and there are lots of opportunities across the nuclear value chain for women to be involved. In recent decades, more and more women are are now entering the nuclear field and many people are starting to recognise opportunities for women, since the role played by women in the nuclear field enhances the development goals for many countries. In developing countries and in Africa in particular, however, there is a greater need for awareness of women’s involvement in STEM fields in general, and to change prevailing attitudes about women’s participation in the nuclear science and technology in particular. This paper will look at various opportunities women have in the expanding nuclear sector in the continent, and how these opportunities can be utilised, not only for those in sciences but also in business disciplines. The approaches organizations and countries can take in broadening participation of the female gender in the nuclear development in Africa; will also be presented, as well as how to address the challenges faced by women in the dynamic nuclear field. (author)

  5. Present status and needs of human resource development in the nuclear field in the Philippines

    Energy Technology Data Exchange (ETDEWEB)

    Bernido, Corazon C.; Roceles, Pilar C. [Philippine Nuclear Research Institute, Commonwealth Avenue, Diliman, Quezon (Philippines)

    2000-12-01

    The first nuclear power plant was nearing completion. However, due to change in political climate and support for the nuclear power program, this has been mothballed. There is a possibility for the introduction of nuclear power plant in the country's projected energy sources by the year 2020. The country has one research reactor, but at the present time it is undergoing repair and is not operational. The Philippine Nuclear Research Institute (PNRI), an Institute under the Department of Science and Technology (DOST), is the sole government agency mandated by the law to take charge of all matters pertaining to nuclear science and technology, and the regulation of nuclear energy. There is one another government agency, the Radiation Health Service (RHS) of the Department of Health, which is responsible for regulating the use and application of X-rays and non-ionizing radiation. The PNRI conducts national training courses in nuclear science and technology, and radiation protection to users of radioisotopes. Individual courses are outlined in the paper. Up to the present time, around 7,300 have participated in national training courses conducted by PNRI. Distributions of PNRI trainees are: 53 % for industrial, 12 % medical, 12 % for academe, and 23 % for others. Nuclear science and technology education in schools and universities are presented. The International Atomic Energy Agency (IAEA) training activities availed 77 % of the total foreign training from 1993 to 1998; Japan follows next at 20 %; and others comprise the remaining 3 %. An approach to training and human resources development, which could reach out to more target trainees, is Distance Learning. In 1998, as a part of a Regional Cooperative Agreement (RCA) and IAEA project, the Philippines participated in the trial of distance learning modules in radiation protection. The distance learning modules were developed at the Australian Nuclear Science and Technology Organization (ANSTO). These modules will

  6. Present status and needs of human resource development in the nuclear field in the Philippines

    International Nuclear Information System (INIS)

    Bernido, Corazon C.; Roceles, Pilar C.

    2000-01-01

    The first nuclear power plant was nearing completion. However, due to change in political climate and support for the nuclear power program, this has been mothballed. There is a possibility for the introduction of nuclear power plant in the country's projected energy sources by the year 2020. The country has one research reactor, but at the present time it is undergoing repair and is not operational. The Philippine Nuclear Research Institute (PNRI), an Institute under the Department of Science and Technology (DOST), is the sole government agency mandated by the law to take charge of all matters pertaining to nuclear science and technology, and the regulation of nuclear energy. There is one another government agency, the Radiation Health Service (RHS) of the Department of Health, which is responsible for regulating the use and application of X-rays and non-ionizing radiation. The PNRI conducts national training courses in nuclear science and technology, and radiation protection to users of radioisotopes. Individual courses are outlined in the paper. Up to the present time, around 7,300 have participated in national training courses conducted by PNRI. Distributions of PNRI trainees are: 53 % for industrial, 12 % medical, 12 % for academe, and 23 % for others. Nuclear science and technology education in schools and universities are presented. The International Atomic Energy Agency (IAEA) training activities availed 77 % of the total foreign training from 1993 to 1998; Japan follows next at 20 %; and others comprise the remaining 3 %. An approach to training and human resources development, which could reach out to more target trainees, is Distance Learning. In 1998, as a part of a Regional Cooperative Agreement (RCA) and IAEA project, the Philippines participated in the trial of distance learning modules in radiation protection. The distance learning modules were developed at the Australian Nuclear Science and Technology Organization (ANSTO). These modules will be

  7. Perfectionistic Self-Presentation in Children and Adolescents: Development and Validation of the Perfectionistic Self-Presentation Scale--Junior Form

    Science.gov (United States)

    Hewitt, Paul L.; Blasberg, Jonathan S.; Flett, Gordon L.; Besser, Avi; Sherry, Simon B.; Caelian, Carmen; Papsdorf, Michael; Cassels, Tracy G.; Birch, Susan

    2011-01-01

    Research on adults indicates that perfectionistic self-presentation, the interpersonal expression of one's perfection, is associated with a variety of psychopathological outcomes independent of trait perfectionism and Big Five traits. The current article reports on the development and evidence for the validity of the subtest score interpretations…

  8. Present State and Future Developments in Mechatronics and it's Influence on Fluid Power Systems

    DEFF Research Database (Denmark)

    Christensen, Georg Kronborg; Zhou, Jianjun; Conrad, Finn

    1998-01-01

    with electronics, software and mechanics. This synergetic integration is often called Mechatronics.The topic which is rather widespread will be treated in three sections: I) General overview of mechatronics and fluid power. In this section the general trends of mechatronics in fluid power is considered by relating...... trends in the neighbouring fields of software and electronic hardware to fluid power developments. II) Mechatronic case stories from IKS In this section the results of a conceptual design study : "Design of a frequency converter based hydraulic power supply" is presented together with a more detailed......This paper tries to sketch the outlines for the future of : Fluid Power Control under the influence of the rapid advances of computer hardware and software technologies. The influences, when they improve the performance of fluid power, are seen as a synergetic integration of fluid power...

  9. Applied and industrial activities at the ESRF: Present status and future development

    International Nuclear Information System (INIS)

    Doucet, Jean

    2003-01-01

    Be it proteins, new superconductors, polymers or ferro-magnetic compounds, fundamental research is laying foundations for possible technical applications as well as industrial exploitation. At the ESRF, industrial companies can be involved in two main ways, depending on the type of research they are interested in. The first concerns beam time allocation for non-proprietary and fully-published research, the procedure is the same as for public laboratories. The second concerns the proprietary research, for which a fee is charged and where results are kept confidential. The use of synchrotron radiation for the characterisation of materials is certain to play a crucial role in the development of new materials in the close future. It is a policy of the ESRF that European industry should share the benefit of its facilities. A survey of the today industrial activity at the ESRF and of its perspective in near future is presented

  10. Present status of developments in physical sorption cooling for space applications

    Science.gov (United States)

    Benthem, B.; Doornink, J.; Boom, E.; Holland, H. J.; Lerou, P. P. P. M.; Burger, J. F.; ter Brake, H. J. M.

    2014-11-01

    A sorption cooler uses the Joule-Thomson effect for cooling a gas by expanding it through a flow restriction. The flow of gas is sustained by a compressor consisting of one or more sorption cells, which cyclically adsorb and desorb gas according to the fully reversible process of physical sorption. The technology has been shown to provide active cooling in the cryogenic temperature range without exporting vibrations or electromagnetic interference. Due to full reversibility of the process and the absence of moving parts (apart from check valves, which open and close with a very low frequency), such a cooler has the potential for a very long life and high reliability. This paper starts with a recapitulation of the principles of physical sorption cooling followed by an overview of the strengths and weaknesses of the technology in relation to other space cooling technologies, such as pulse-tube cooling and Stirling cooling. Next, the present status of physical sorption cooling technology is presented based on developments previously and currently being performed by the University of Twente, Dutch Space and Kryoz Technologies. A summary will be given of the various existing demonstrator- and lab-models which have been built, along with an overview of the tests which have so far been performed. The central result of this paper is an assessment of the current Technology Readiness Level (TRL) of various sorption cooler configurations, along with their application range in terms of temperatures, heat loads and mission profile. Finally, an outline is given on the way forward currently being pursued by the developers to achieve full maturity of the technology.

  11. NATURE CONSERVATION MOVEMENT IN THE WORLD: ITS HISTORICAL DEVELOPMENT AND PRESENT SITUATION

    Directory of Open Access Journals (Sweden)

    Oğuz Kurdoğlu

    2007-04-01

    Full Text Available Although nature conservation is a well recognized topic at present, it is not a new phenomenon. Throughout history, there are numerous examples of efforts made by governments, rulers, or individual land owners to protect certain land areas that possessed unique natural values. While many of these areas were actually isolated as game preserves for hunting, they were also designed to conserve wildlife. The establishment of Yellowstone National Park in 1972 marks the modern concept of a national park as it was designed on a very large protected natural area. Presently, one of the most efficient ways for nature protection is “area conservation approach” that many organizations have been developing various systems and categories about. Unfortunately, in spite of such improvements and the extension of the protected area network, many of these areas are not properly protected and/or managed in some countries. This study summarizes the historical evolution of nature conservation systems and strategies in the world with the related international legislative aspects as well. As it stated in this paper, USA and Europa have a well known history on nature conservation and show great concern in respect to participating to the international convention and arrangements.

  12. Past, present and future of nutrigenomics and its influence on drug development.

    Science.gov (United States)

    Lundstrom, Kenneth

    2013-03-01

    The importance of nutrition in disease prevention and treatment has gained much attention with the emergence of next generation sequence technologies allowing full-genome sequencing at reduced cost in weeks rather than months. The vast genetic information needs to be efficiently channeled into a useful format to provide applicability for improved health and treatment of disease. Recently, it also led to the birth of nutrigenomics, which facilitates the investigation of the effects of nutrition on gene expression and beyond. At present, a number of studies have showed the effect of nutrition on gene expression in health and disease. For instance, weight loss and as importantly weight keeping has been demonstrated to be efficiently achieved in obesity treatment through personalized diet planning. Likewise, intensive dietary interventions have showed a significant effect on the expression pattern on cancer-related genes in prostate cancer patients. Epigenetic modifications such as DNA methylation, histone modifications, and microRNA-based gene silencing are strongly affected by nutritional intake. Better understanding of the human genome will further accelerate nutrigenomics applications and the development of nutritional modifications including personalized nutrition for our well-being and will also present a strong influence on future drug discovery.

  13. Development of Molecularly Imprinted Polymers to Target Polyphenols Present in Plant Extracts

    Directory of Open Access Journals (Sweden)

    Catarina Gomes

    2017-11-01

    Full Text Available The development of molecularly imprinted polymers (MIPs to target polyphenols present in vegetable extracts was here addressed. Polydatin was selected as a template polyphenol due to its relatively high size and amphiphilic character. Different MIPs were synthesized to explore preferential interactions between the functional monomers and the template molecule. The effect of solvent polarity on the molecular imprinting efficiency, namely owing to hydrophobic interactions, was also assessed. Precipitation and suspension polymerization were examined as a possible way to change MIPs morphology and performance. Solid phase extraction and batch/continuous sorption processes were used to evaluate the polyphenols uptake/release in individual/competitive assays. Among the prepared MIPs, a suspension polymerization synthesized material, with 4-vinylpyridine as the functional monomer and water/methanol as solvent, showed a superior performance. The underlying cause of such a significant outcome is the likely surface imprinting process caused by the amphiphilic properties of polydatin. The uptake and subsequent selective release of polyphenols present in natural extracts was successfully demonstrated, considering a red wine solution as a case study. However, hydrophilic/hydrophobic interactions are inevitable (especially with complex natural extracts and the tuning of the polarity of the solvents is an important issue for the isolation of the different polyphenols.

  14. Nuclear energy, today and tomorrow. Present status of development and utilization in Japan 1995

    International Nuclear Information System (INIS)

    1995-01-01

    The world population has exceeded 5 billion, today, and it is estimated to reach 10 billion in the middle of the twenty first century. Because of such rapid increase of population, the world energy consumption is estimated to increase tremendously. Furthermore, there are problems of limited energy resources from oil and coal down, how to respond to environment problems such as global warming, acid rain caused by fossil fuel burning, followed by carbon dioxide discharge. Under such circumstances of global scale problems, the nuclear power generation that is excellent in stable nature of supply, economic advantage, less effect to the environment, supplies about 20 % of the total power generation in the world. In our country, some 30 % of the total power generation relies on the nuclear power, as an indispensable power source. Radiation utilization, together with the nuclear power generation, is an important pillar of development and utilization of nuclear energy, and has penetrated deeply in the life of the people, in the fields of industry, agriculture, medicine and environmental protection, and it is contributing to realize affluent life to a great extent. Thus, expectations to the nuclear energy seem to grow larger and larger in future. The publication introduces present status and future potential of the development and utilization of the nuclear energy in Japan, including the basic idea and concrete plans shown in the Long-Term Program. (J.P.N.)

  15. Present state and near future prospect of nuclear fusion research and development

    International Nuclear Information System (INIS)

    Kurihara, Kenichi

    1995-01-01

    In place of the cold war, the destruction of global environment has become to be recognized as the largest threat for mankind. In such circumstance, nuclear fusion has the features that it does not release the substances which cause global warming and acid rain, the fuel resources are contained in seawater, therefore, infinite and distributed uniformly and so on. Nuclear fusion is the fundamental energy source in the sun and space, and aiming at realizing this reaction on the earth as early as possible, now is the time to show the physical and engineering feasibility of nuclear fusion power generation. The progress of the research and development of nuclear fusion is described. At present, the critical plasma condition has been attained for a moment in tokamak type nuclear fusion devices, and the attainment of the self ignition condition is studied. As the methods of realizing nuclear fusion reaction, deuterium-tritium reaction is utilized, and magnetic field confinement and inertia confinement methods are regarded as promising. The performance attained by the various nuclear fusion devices in the world is shown. The elucidation of the factors that decide plasma performance is very difficult. The outline of the ITER project is mentioned. The third stage plan of research and development is explained. The prospect for near future is the start of experiment with the ITER at the beginning of the next century. (K.I.)

  16. Present status and future plan of development on National Nuclear Forensics Library at JAEA

    International Nuclear Information System (INIS)

    Kimura, Yoshiki; Shinohara, Nobuo; Funatake, Yoshio; Sato, Kaneaki; Toda, Nobufumi; Shinoda, Yoshiharu; Watahiki, Masaru; Kuno, Yusuke

    2013-01-01

    Japan Atomic Energy Agency (JAEA) has initiated R and D project on nuclear forensics technology such as analytical technologies towards the establishment of nuclear forensics capabilities in Japan. National Nuclear Forensics Library (NNFL) is one of the fundamental nuclear forensics capabilities and a prototype NNFL has been developed as one topic of the R and D project at JAEA. Main objective of NNFL is to determine whether a seized nuclear or other radioactive material from nuclear security event (e.g. illicit trafficking) is originated from one's country or not. Analytical data of the seized material are compared with the existing materials populated in a NNFL, and its attributions such as origin and history will be identified. This paper describes the current status and future plan on the development of prototype NNFL. The outline and the results of the participation in an international table top exercise on NNFL named 'Galaxy Serpent' are also reported in the present paper. (author)

  17. Development of a Virtual Museum Including a 4d Presentation of Building History in Virtual Reality

    Science.gov (United States)

    Kersten, T. P.; Tschirschwitz, F.; Deggim, S.

    2017-02-01

    In the last two decades the definition of the term "virtual museum" changed due to rapid technological developments. Using today's available 3D technologies a virtual museum is no longer just a presentation of collections on the Internet or a virtual tour of an exhibition using panoramic photography. On one hand, a virtual museum should enhance a museum visitor's experience by providing access to additional materials for review and knowledge deepening either before or after the real visit. On the other hand, a virtual museum should also be used as teaching material in the context of museum education. The laboratory for Photogrammetry & Laser Scanning of the HafenCity University Hamburg has developed a virtual museum (VM) of the museum "Alt-Segeberger Bürgerhaus", a historic town house. The VM offers two options for visitors wishing to explore the museum without travelling to the city of Bad Segeberg, Schleswig-Holstein, Germany. Option a, an interactive computer-based, tour for visitors to explore the exhibition and to collect information of interest or option b, to immerse into virtual reality in 3D with the HTC Vive Virtual Reality System.

  18. Imaging of murine embryonic cardiovascular development using optical coherence tomography (Conference Presentation)

    Science.gov (United States)

    Huang, Yongyang; Degenhardt, Karl R.; Astrof, Sophie; Zhou, Chao

    2016-03-01

    We have demonstrated the capability of spectral domain optical coherence tomography (SDOCT) system to image full development of mouse embryonic cardiovascular system. Monitoring morphological changes of mouse embryonic heart occurred in different embryonic stages helps identify structural or functional cardiac anomalies and understand how these anomalies lead to congenital heart diseases (CHD) present at birth. In this study, mouse embryo hearts ranging from E9.5 to E15.5 were prepared and imaged in vitro. A customized spectral domain OCT system was used for imaging, with a central wavelength of 1310nm, spectral bandwidth of ~100nm and imaging speed of 47kHz A-scans/s. Axial resolution of this system was 8.3µm in air, and transverse resolution was 6.2 µm with 5X objective. Key features of mouse embryonic cardiovascular development such as vasculature remodeling into circulatory system, separation of atria and ventricles and emergence of valves could be clearly seen in three-dimensional OCT images. Optical clearing was applied to overcome the penetration limit of OCT system. With high resolution, fast imaging speed, 3D imaging capability, OCT proves to be a promising biomedical imaging modality for developmental biology studies, rivaling histology and micro-CT.

  19. Develop Oral Presentation Skills through Accounting Curriculum Design and Course-Embedded Assessment

    Science.gov (United States)

    Kerby, Debra; Romine, Jeff

    2010-01-01

    At present, oral communication and presentation skills are important components of accounting education. Students can improve their oral presentation skills when they know the expectations for effective presentations, give multiple group and individual presentations, and experience consistent instructor feedback. The authors use a case study…

  20. Present status and needs of human resource development in nuclear field in Korea

    Energy Technology Data Exchange (ETDEWEB)

    Choi, Young-Myung; Lee, Eui-Jin [Nuclear Training Center, Korea Atomic Energy Research Institute, Taejon (Korea)

    2000-12-01

    The Nuclear Training Center (NTC) of KAERI (Korea Atomic Energy Research Institute) began training technical personnel in the field of radioisotope utilization and radiation protection during the 1960's. During the first stage of the nation's nuclear power project in the 1970's, the main effort of the Center focused on training those in nuclear power and nuclear engineering. During a stage of increased technical self-reliance in the 1980's, the Center extended its training role to implement more specific training courses on nuclear power and safety fields. Since 1983, the Center has been empowered at the request of government to provide retraining courses for nuclear-related license holders and qualified engineers. The Center has offered IAEA regional training course annually for Asia and Pacific region member states since 1988. Since 1967, the total number of trainees is up to 27,777 as of the end of 1998. KEPCO (Korea Electric Power Corporation) started Nuclear Power Education Center (NPEC) in 1990. The outlines of KEPCO's in-house training programs are presented in the report. The reactor operators, and the persons engaged in nuclear fuel materials, radioisotope or radiation generating devices need particular licenses in accordance with Korean Atomic Energy Laws and Regulation. NTC/KAERI and NPEC/KEPCO should report annual retraining programs for licensed personnel to Ministry Of Science and Technology (MOST) every year. The outlines of projects, which are directly related to human resources development in nuclear field in Korea, are described in the paper. The International Atomic Energy Agency (IAEA) has made efforts to provide training programs for technical personnel of developing countries for the peaceful uses of nuclear energy. Korea has also received lots of assistance for her manpower development from the Agency. Korea is now on the verge of transforming herself from a technology recipient country in some practical and

  1. Present status and needs of human resource development in nuclear field in Korea

    International Nuclear Information System (INIS)

    Choi, Young-Myung; Lee, Eui-Jin

    2000-01-01

    The Nuclear Training Center (NTC) of KAERI (Korea Atomic Energy Research Institute) began training technical personnel in the field of radioisotope utilization and radiation protection during the 1960's. During the first stage of the nation's nuclear power project in the 1970's, the main effort of the Center focused on training those in nuclear power and nuclear engineering. During a stage of increased technical self-reliance in the 1980's, the Center extended its training role to implement more specific training courses on nuclear power and safety fields. Since 1983, the Center has been empowered at the request of government to provide retraining courses for nuclear-related license holders and qualified engineers. The Center has offered IAEA regional training course annually for Asia and Pacific region member states since 1988. Since 1967, the total number of trainees is up to 27,777 as of the end of 1998. KEPCO (Korea Electric Power Corporation) started Nuclear Power Education Center (NPEC) in 1990. The outlines of KEPCO's in-house training programs are presented in the report. The reactor operators, and the persons engaged in nuclear fuel materials, radioisotope or radiation generating devices need particular licenses in accordance with Korean Atomic Energy Laws and Regulation. NTC/KAERI and NPEC/KEPCO should report annual retraining programs for licensed personnel to Ministry Of Science and Technology (MOST) every year. The outlines of projects, which are directly related to human resources development in nuclear field in Korea, are described in the paper. The International Atomic Energy Agency (IAEA) has made efforts to provide training programs for technical personnel of developing countries for the peaceful uses of nuclear energy. Korea has also received lots of assistance for her manpower development from the Agency. Korea is now on the verge of transforming herself from a technology recipient country in some practical and fundamental fields. The

  2. The Earthcare Cloud Profiling Radar, its PFM development status (Conference Presentation)

    Science.gov (United States)

    Nakatsuka, Hirotaka; Tomita, Eichi; Aida, Yoshihisa; Seki, Yoshihiro; Okada, Kazuyuki; Maruyama, Kenta; Ishii, Yasuyuki; Tomiyama, Nobuhiro; Ohno, Yuichi; Horie, Hiroaki; Sato, Kenji

    2016-10-01

    The Earth Clouds, Aerosols and Radiation Explorer (EarthCARE) mission is joint mission between Europe and Japan for the launch year of 2018. Mission objective is to improve scientific understanding of cloud-aerosol-radiation interactions that is one of the biggest uncertain factors for numerical climate and weather predictions. The EarthCARE spacecraft equips four instruments such as an ultra violet lidar (ATLID), a cloud profiling radar (CPR), a broadband radiometer (BBR), and a multi-spectral imager (MSI) and perform complete synergy observation to observe aerosols, clouds and their interactions simultaneously from the orbit. Japan Aerospace Exploration Agency (JAXA) is responsible for development of the CPR in this EarthCARE mission and the CPR will be the first space-borne W-band Doppler radar. The CPR is defined with minimum radar sensitivity of -35dBz (6dB better than current space-borne cloud radar, i.e. CloudSat, NASA), radiometric accuracy of 2.7 dB, and Doppler velocity measurement accuracy of less than 1.3 m/s. These specifications require highly accurate pointing technique in orbit and high power source with large antenna dish. JAXA and National Institute of Information and Communications Technology (NICT) have been jointly developed this CPR to meet these strict requirements so far and then achieved the development such as new CFRP flex-core structure, long life extended interaction klystron, low loss quasi optical feed technique, and so on. Through these development successes, CPR development phase has been progressed to critical design phase. In addition, new ground calibration technique is also being progressed for launch of EarthCARE/CPR. The unique feature of EarthCARE CPR is vertical Doppler velocity measurement capability. Vertical Doppler velocity measurement is very attractive function from the science point of view, because vertical motions of cloud particles are related with cloud microphysics and dynamics. However, from engineering point of

  3. [The historical background and present development of evidence-based healthcare and clinical nursing].

    Science.gov (United States)

    Tsai, Jung-Mei

    2014-12-01

    Evidence-based healthcare (EBHC) emphasizes the integration of the best research evidence with patient values, specialist suggestions, and clinical circumstances during the process of clinical decision-making. EBHC is a recognized core competency in modern healthcare. Nursing is a professional discipline of empirical science that thrives in an environment marked by advances in knowledge and technology in medicine as well as in nursing. Clinical nurses must elevate their skills and professional qualifications, provide efficient and quality health services, and promote their proficiency in EBHC. The Institute of Medicine in the United States indicates that evidence-based research results often fail to disseminate efficiently to clinical decision makers. This problem highlights the importance of better promoting the evidence-based healthcare fundamentals and competencies to frontline clinical nurses. This article describes the historical background and present development of evidence-based healthcare from the perspective of modern clinical nursing in light of the importance of evidence-based healthcare in clinical nursing; describes the factors associated with evidence-based healthcare promotion; and suggests strategies and policies that may improve the promotion and application of EBHC in clinical settings. The authors hope that this paper provides a reference for efforts to improve clinical nursing in the realms of EBHC training, promotion, and application.

  4. Markets, Availability, Notice, and Technical Performance of Terahertz Systems: Historic Development, Present, and Trends

    Science.gov (United States)

    Hochrein, Thomas

    2015-03-01

    Although a lot of work has already been done under the older terms "far infrared" or "sub-millimeter waves", the term "terahertz" stands for a novel technique offering many potential applications. The latter term also represents a new generation of systems with the opportunity for coherent, time-resolved detection. In addition to the well-known technical opportunities, an historical examination of Internet usage, as well as the number of publications and patent applications, confirms ongoing interest in this technique. These activities' annual growth rate is between 9 % and 21 %. The geographical distribution shows the center of terahertz activities. A shift from the scientific to more application-oriented research can be observed. We present a survey among worldwide terahertz suppliers with special focus on the European region and the use of terahertz systems in the field of measurement and analytical applications. This reveals the current state of terahertz systems' commercial and geographical availability as well as their costs, target markets, and technical performance. Component cost distribution using the example of an optical pulsed time-domain terahertz system gives an impression of the prevailing cost structure. The predication regarding prospective market development, decreasing system costs and higher availability shows a convenient situation for potential users and interested customers. The causes are primarily increased competition and larger quantities in the future.

  5. Monitoring in-vitro bovine embryo development during the first days after fertilization (Conference Presentation)

    Science.gov (United States)

    Kandel, Mikhail E.; Rubessa, Marcello; Fernandes, Daniel; Nguyen, Tan H.; Wheeler, Matthew B.; Popescu, Gabriel

    2016-03-01

    Conventional label-based contrast enhancement techniques (e.g., fluorescence) frequently modify the genetic makeup of tagged cells, making them poor candidates for use in in-vitro fertilization applications. Instead, we choose a label-free form of contrast, based on interferometric imaging, sensitive to optical path length differences. Compared to, single HeLa cells, typical mammalian ova and embryos are more than an order of magnitude thicker. As a result, regions of large phase variation lead to phase wrapping and an overall reduction in signal intensity occurs due to multiple scattering. These effects manifest themselves in low-spatial frequencies (blurs), with the desired details buried in the background. We present a phase shifting interferometer that yields the derivative of the phase, a quantity whose value is particularly sensitive to local variations and fine details. We demonstrate that our new real-time imaging platform is valuable in measuring the multiday development of bovine embryos. Reconstructing the derivative of the image phase and amplitude, we characterize the motion of previously low-contrast structures, which are relevant for embryo viability tests.

  6. The present state and future of the development of dimension stone mining in Slovak conditions

    Directory of Open Access Journals (Sweden)

    Viliam Žiaran

    2005-03-01

    Full Text Available In comparing to both ores and energetical minerals there are occurences of extremly rich non-methallics minerals on the Slovak territory. These minerals represent very large-scale sortiment with a considerable amount of verified reserves. Reserves of magnesite, salt rock, dolomite, limestone, talc, bentonite, clays and another construction minerals present many possibilities of their industrial utilization. A specific case is the mining of dimension stones such as stable ingeneous,sedimentary and metamorphic rocks that are mined in the open-pit blocks. Applicable to the production of both ingeneous stone and gross stone [3].The open-pit mining and dimension stone processing by the both above mentioned stone productions forms are focused mainly to the external and internal building industry. Despite of the fact that the natural reserves of dimension stone are limited at the Slovak territory, being distributed at large numbers of open-pits mines, from the point of view of the next development of the dimension stone industry its technical and economic vitalitycan be expected. The paper deals with both the technological and ecological mining problems of dimension stone and shows the possibilities how to improve both the works productivity and quality of products including the ecological impacts by the dimension stone mining.

  7. Methodological developments in searching for studies for systematic reviews: past, present and future?

    Science.gov (United States)

    Lefebvre, Carol; Glanville, Julie; Wieland, L Susan; Coles, Bernadette; Weightman, Alison L

    2013-09-25

    The Cochrane Collaboration was established in 1993, following the opening of the UK Cochrane Centre in 1992, at a time when searching for studies for inclusion in systematic reviews was not well-developed. Review authors largely conducted their own searches or depended on medical librarians, who often possessed limited awareness and experience of systematic reviews. Guidance on the conduct and reporting of searches was limited. When work began to identify reports of randomized controlled trials (RCTs) for inclusion in Cochrane Reviews in 1992, there were only approximately 20,000 reports indexed as RCTs in MEDLINE and none indexed as RCTs in Embase. No search filters had been developed with the aim of identifying all RCTs in MEDLINE or other major databases. This presented The Cochrane Collaboration with a considerable challenge in identifying relevant studies.Over time, the number of studies indexed as RCTs in the major databases has grown considerably and the Cochrane Central Register of Controlled Trials (CENTRAL) has become the best single source of published controlled trials, with approximately 700,000 records, including records identified by the Collaboration from Embase and MEDLINE. Search filters for various study types, including systematic reviews and the Cochrane Highly Sensitive Search Strategies for RCTs, have been developed. There have been considerable advances in the evidence base for methodological aspects of information retrieval. The Cochrane Handbook for Systematic Reviews of Interventions now provides detailed guidance on the conduct and reporting of searches. Initiatives across The Cochrane Collaboration to improve the quality inter alia of information retrieval include: the recently introduced Methodological Expectations for Cochrane Intervention Reviews (MECIR) programme, which stipulates 'mandatory' and 'highly desirable' standards for various aspects of review conduct and reporting including searching, the development of Standard Training

  8. The Global Network of Isotopes in Precipitation after 55 years: assessing past, present and future developments

    Science.gov (United States)

    Terzer, Stefan; Araguas-Araguas, Luis; Wassenaar, Leonard I.; Aggarwal, Pradeep K.

    2015-04-01

    The Global Network of Isotopes in Precipitation (GNIP) is a global observation programme operated by the International Atomic Energy Agency (IAEA), in cooperation with the World Meteorological Organization (WMO) and more than 100 contributing institutions worldwide. GNIP has been the primary repository for baseline stable (δ18O, δ2H) and radioactive (3H) isotope data since its foundation in 1960. The impetus for GNIP was the monitoring of radioactive fallout from atmospheric thermonuclear testing and resulting tritium levels of precipitation, but tritium together with stable isotopes was recognized as a key to understanding hydrological processes. Later, new applications were developed focusing on hydrometeorology and paleoclimatic research. Increasingly, GNIP data are being used more widely in ecological and forensic investigations, e.g. for tracking of migratory animals. The GNIP database comprises more than 135,000 isotopic records (δ18O: 63,000; δ2H: 55,000; 3H: 63,000) of monthly composite precipitation samples from more than 1,000 stations worldwide. About 300 stations are currently active for stable isotopes and ca. 100 for tritium. Data for most of the active stations is available up to 2013. Several national isotopic observation networks (e.g. in Austria, Australia, China or the United States of America) exist besides GNIP, complementing precipitation isotope data at national levels. The spatially and temporally discrete nature of the GNIP dataset induces coverage gaps. Recently, highly-resolved gridded datasets were established to help overcome this deficiency through geostatistical prediction models. These 'isoscape' (isotopic landscapes) are based on combinations of multiple regression and interpolation methods, with a range of parameterization available at regional and global levels. Attempts to bridge the gap between 'one-size-fits-all' global parameterization and improved predictions at regional and local levels led to the establishment of a

  9. Environmental impact assessment (EIA) in development cooperation. A presentation of development challenges and research issues in developing countries and donor agencies

    Energy Technology Data Exchange (ETDEWEB)

    Kristoffersen, Harald

    1997-12-31

    This document discusses some development challenges and research needs related to environmental impact assessment (EIA) in development cooperation. After a general introduction to basic principles of EIA, the document deals with some general conditions for EIA in developing countries and in donor agencies. Through a presentation of experiences with EIA from selected donor agencies (with emphasis on NORAD) the report ends up with focusing on some research issues that may come up with recommendations for improving EIA practices in developing countries and donor agencies. 37 refs., 6 figs., 3 refs.

  10. Three-day dendritic cells for vaccine development: Antigen uptake, processing and presentation

    Directory of Open Access Journals (Sweden)

    Schendel Dolores J

    2010-09-01

    Full Text Available Abstract Background Antigen-loaded dendritic cells (DC are capable of priming naïve T cells and therefore represent an attractive adjuvant for vaccine development in anti-tumor immunotherapy. Numerous protocols have been described to date using different maturation cocktails and time periods for the induction of mature DC (mDC in vitro. For clinical application, the use of mDC that can be generated in only three days saves on the costs of cytokines needed for large scale vaccine cell production and provides a method to produce cells within a standard work-week schedule in a GMP facility. Methods In this study, we addressed the properties of antigen uptake, processing and presentation by monocyte-derived DC prepared in three days (3d mDC compared with conventional DC prepared in seven days (7d mDC, which represent the most common form of DC used for vaccines to date. Results Although they showed a reduced capacity for spontaneous antigen uptake, 3d mDC displayed higher capacity for stimulation of T cells after loading with an extended synthetic peptide that requires processing for MHC binding, indicating they were more efficient at antigen processing than 7d DC. We found, however, that 3d DC were less efficient at expressing protein after introduction of in vitro transcribed (ivtRNA by electroporation, based on published procedures. This deficit was overcome by altering electroporation parameters, which led to improved protein expression and capacity for T cell stimulation using low amounts of ivtRNA. Conclusions This new procedure allows 3d mDC to replace 7d mDC for use in DC-based vaccines that utilize long peptides, proteins or ivtRNA as sources of specific antigen.

  11. Development and characterisation of a brain tumour mimicking protoporphyrin IX fluorescence phantom (Conference Presentation)

    Science.gov (United States)

    Xie, Yijing; Tisca, Cristiana; Peveler, William; Noimark, Sacha; Desjardins, Adrien E.; Parkin, Ivan P.; Ourselin, Sebastien; Vercauteren, Tom

    2017-02-01

    5-ALA-PpIX fluorescence-guided brain tumour resection can increase the accuracy at which cancerous tissue is removed and thereby improve patient outcomes, as compared with standard white light imaging. Novel optical devices that aim to increase the specificity and sensitivity of PpIX detection are typically assessed by measurements in tissue-mimicking optical phantoms of which all optical properties are defined. Current existing optical phantoms specified for PpIX lack consistency in their optical properties, and stability with respect to photobleaching, thus yielding an unstable correspondence between PpIX concentration and the fluorescence intensity. In this study, we developed a set of aqueous-based phantoms with different compositions, using deionised water or PBS buffer as background medium, intralipid as scattering material, bovine haemoglobin as background absorber, and either PpIX dissolved in DMSO or a novel nanoparticle with similar absorption and emission spectrum to PpIX as the fluorophore. We investigated the phantom stability in terms of aggregation and photobleaching by comparing with different background medium and fluorophores, respectively. We characterised the fluorescence intensity of the fluorescent nanoparticle in different concentration of intralipid and haemoglobin and its time-dependent stability, as compared to the PpIX-induced fluorescence. We corroborated that the background medium was essential to prepare a stable aqueous phantom. The novel fluorescent nanoparticle used as surrogate fluorophore of PpIX presented an improved temporal stability and a reliable correspondence between concentration and emission intensity. We proposed an optimised phantom composition and recipe to produce reliable and repeatable phantom for validation of imaging device.

  12. Information Security: Past, Present and Future - Impact of Developments in Information Technology on Security

    NARCIS (Netherlands)

    Overbeek, P.L.

    1991-01-01

    The development of information security is addressed in relation to the development of information technology. The leading question is: how has information security developed itself so far, and how should it progress to address tomorrow's security needs. An overwiew is given of the use of

  13. PECULIARITIES OF GENDER DISCRIMINATION IN PRESENT-DAY DEVELOPMENT OF UKRAINE AND THE WORLD

    OpenAIRE

    Паламарчук, Наталія Олександрівна; Кришня, Таїсія Олександрівна

    2017-01-01

    The article deals with the features of gender discrimination in modern conditions of the development of Ukraine and the world. For this purpose, the article explores the main aspects of gender inequality in the world to identify the main trends in the development of this problem. Gender inequality in Ukraine and in the world using the third billion index is analyzed. This makes possible to assess the level of efficiency of women's empowerment in the economy. An assessment of the development o...

  14. Towards a set of design principles for developing oral presentation competence: A synthesis of research in higher education

    NARCIS (Netherlands)

    Ginkel, van S.O.; Gulikers, J.T.M.; Biemans, H.J.A.; Mulder, M.

    2015-01-01

    Developing oral presentation competence is an essential objective in higher education. However, a comprehensive picture of effective learning environment characteristics for encouraging oral presentation performance is lacking hitherto. This review identifies and classifies relevant studies with the

  15. Developing Charismatic Delivery through Transformational Presentations: Modeling the Persona of Steve Jobs

    Science.gov (United States)

    Ivic, Rebecca K.; Green, Robert J.

    2012-01-01

    How can public speaking instructors teach students how to be charismatic and confident speakers? The activity presented in this article suggests that instructors foster competent and charismatic presentational skills by having students channel the stylistic capabilities of an exceptional speaker. The activity requires students to take on the…

  16. National Stormwater Calculator: Low Impact Development Stormwater Control Cost Estimation Programming & Future Enhancements - Presentation

    Science.gov (United States)

    The National Stormwater Calculator (NSC) makes it easy to estimate runoff reduction when planning a new development or redevelopment site with low impact development (LID) stormwater controls. The Calculator is currently deployed as a Windows desktop application. The NSC is organ...

  17. MHC class I antigen presentation and implications for developing a new generation of therapeutic vaccines.

    Science.gov (United States)

    Comber, Joseph D; Philip, Ramila

    2014-05-01

    Major histocompatibility complex class I (MHC-I) presented peptide epitopes provide a 'window' into the changes occurring in a cell. Conventionally, these peptides are generated by proteolysis of endogenously synthesized proteins in the cytosol, loaded onto MHC-I molecules, and presented on the cell surface for surveillance by CD8(+) T cells. MHC-I restricted processing and presentation alerts the immune system to any infectious or tumorigenic processes unfolding intracellularly and provides potential targets for a cytotoxic T cell response. Therefore, therapeutic vaccines based on MHC-I presented peptide epitopes could, theoretically, induce CD8(+) T cell responses that have tangible clinical impacts on tumor eradication and patient survival. Three major methods have been used to identify MHC-I restricted epitopes for inclusion in peptide-based vaccines for cancer: genetic, motif prediction and, more recently, immunoproteomic analysis. Although the first two methods are capable of identifying T cell stimulatory epitopes, these have significant disadvantages and may not accurately represent epitopes presented by a tumor cell. In contrast, immunoproteomic methods can overcome these disadvantages and identify naturally processed and presented tumor associated epitopes that induce more clinically relevant tumor specific cytotoxic T cell responses. In this review, we discuss the importance of using the naturally presented MHC-I peptide repertoire in formulating peptide vaccines, the recent application of peptide-based vaccines in a variety of cancers, and highlight the pros and cons of the current state of peptide vaccines.

  18. Radionuclides for therapeutic applications: Biological and medical aspects (present status, development and expectations)

    International Nuclear Information System (INIS)

    Wambersie, A.; Gahbauer, R.A.

    2002-01-01

    Different multidisciplinary therapeutic strategies and technical approaches are used today in cancer therapy. Among the techniques involving ionizing radiation, therapeutic applications of radioactive nuclides deserve a particular interest ; some clinical indications are well established, while several others are now being investigated, and some of them are promising. The efficacy of radionuclides in therapy often depends on technical factors such as specific activity, purity, chemical presentation, availability, etc. These factors are closely related, at least partly, to the production methods. This justifies the organization of the present Consultant's meeting by the IAEA. Brief information on cancer, its socio-economic aspects, and some data concerning cure rate are presented first

  19. SITE-94. Scenario development FEP audit list preparation: methodology and presentation

    International Nuclear Information System (INIS)

    Stenhouse, M.; Chapman, N.; Sumerling, T.

    1993-04-01

    This report concerns a study which is part of the SKI performance assessment project SITE-94. SITE-94 is a performance assessment of a hypothetical repository at a real site. The main objective of the project is to determine how site specific data should be assimilated into the performance assessment process and to evaluate how uncertainties inherent in site characterization will influence performance assessment results. Other important elements of SITE-94 are the development of a practical and defensible methodology for defining, constructing and analyzing scenarios, the development of approaches for treatment of uncertainties , evaluation of canister integrity, and the development and application of an appropriate quality assurance plan for performance assessments

  20. An attempt for faculty development reflecting class-evaluation of presentation software based lectures.

    OpenAIRE

    太田, 伸幸

    2004-01-01

    The purpose of this paper was to aim at an improvement of presentation software based teaching method. "Science of the Mind", a series of lectures in the first semester, was given by using presentation software Power Point. The improvement proposal for the lectures was made by examining class-evaluation of the lectures. In the second semester, two series of lectures, "Science of the Mind" and "Educational Psychology" were given according to the improved method. Significant improvement was fou...

  1. Development of Antigen Presenting Cells for Adoptive Immunotherapy in Prostate Cancer

    National Research Council Canada - National Science Library

    Oelke, Mathias

    2006-01-01

    While adoptive immunotherapy holds promise as a treatment for cancer and infectious diseases, development has been impeded by the lack of reproducible methods for generating therapeutic numbers of antigen-specific CD8+ CTL...

  2. Care Support Activities for Elderly Koreans in Japan:The Historical Development and Present Challenges(2)

    OpenAIRE

    趙, 文基

    2012-01-01

    This paper explores the historical development of elderly care focusing on the activities of the Federation of Korean Residents in Japan (CHONGRYON).How has the ethnic Korean elderly care system developed in Japan? CHONGRYON's data of social welfare facilities for the elderly enable us to understand care support activities and the circumstances for this minority elderly group in Japan. I also surveyed this organization and qualitatively analyzed the publications (1998-2010) of their social mo...

  3. PRODUCTION OF CATHODES AND HIGH PURITY TARGETS OF CHEMICALLY ACTIVE METALS BY MEANS OF ELECTRONIC-RAY MELTING

    Directory of Open Access Journals (Sweden)

    A. V. Alifanov

    2007-01-01

    Full Text Available The technical process of production and restoration of worn cathodes and targets of chemically active metals (Ti, Zr, V and others with the help of cathode ray in vacuum is developed. Regenerating of worn cathodes, targets is carried out by means of insertion in chill of worn base and successive cathode ray deposition on certain places of required quantity of metal (from 2 till 50mm.

  4. Overweight and obese infants present lower cognitive and motor development scores than normal-weight peers.

    Science.gov (United States)

    Camargos, Ana Cristina Resende; Mendonça, Vanessa Amaral; Andrade, Camila Alves de; Oliveira, Katherine Simone Caires; Lacerda, Ana Cristina Rodrigues

    2016-12-01

    Compare the cognitive and motor development in overweight/obese infants versus normal-weight peers and investigate the correlation of body weight, body length and body mass index with cognitive and motor development. We conducted a cross-sectional study with 28 overweight/obese infants and 28 normal-weight peers between 6 and 24 months of age. Both groups were evaluated with cognitive and motor scales of the Bayley-III infant development test. The t-test for independent samples was performed to compare the groups, and the Spearman correlation was used to verify the association between variables. Overweight/obese infants showed lower cognitive and motor composite scores than their normal-weight peers. A significant negative association was found of body weight and body length with cognitive development and of body mass index with motor development. This is the first study that found an effect on both cognitive and motor development in overweight/obese infants when compared with normal-weight peers between 6 and 24 months of age. Copyright © 2016 Elsevier Ltd. All rights reserved.

  5. Present status of uranium-plutonium mixed carbide fuel development for LMFBRs

    International Nuclear Information System (INIS)

    Handa, Muneo; Suzuki, Yasufumi

    1984-01-01

    The feature of carbide fuel is that it has the doubling time as short as about 13 years, that is, close to one half as compared with oxide fuel. The development of the carbide fuel in the past 10 years has been started in amazement. Especially in the program of new fuel development in USA started in 1974, He and Na bond fuel attained the burnup of 16 a/o without causing the breaking of cladding tubes. In 1984, the irradiation of the assembly composed of 91 fuel pins in the FFTF is expected. On the other hand in Japan, the fuel research laboratory was constructed in 1974 in the Oarai Laboratory, Japan Atomic Energy Research Institute, to carry out the studies on carbide fuel. In the autumn of 1982, two carbide fuel pins with different chemical composition have been successfully made. Accordingly, the recent status of the development is explained. The uranium-plutonium mixed carbide fuel is suitable to liquid metal-cooled fast breeder reactors because of large heat conductivity and the high density of nuclear fission substances. The thermal and nuclear characteristics of carbide fuel, the features of the reactor core using carbide fuel, the chemical and mechanical interaction of fuel and cladding tubes, the selection of bond materials, the manufacturing techniques for the fuel, the development of the analysis code for fuel behavior, and the research and development of carbide fuel in Japan are described. (Kako, I.)

  6. Modern light water reactors - EPR and SWR 1000. Present status and possibilities of development and application

    International Nuclear Information System (INIS)

    Brettschuh, W.; Schneider, D.

    2002-01-01

    Framatome ANP has focused its efforts on two development projects in the field of light water reactor technology: the EPR (capacity 1500-1600 MW) and the SWR1000. The main goals pursued in developing the two product lines are: to increase nuclear plant safety even further compared to existing plants and to achieve power generating costs that are competitive with those of fossil-fired power plants. Some key advances made during the development that are particularly characteristic of the EPR and SWR are discussed. For the EPR the main safety systems are: double wall containment, containment heat removal system, four train redundancy for main safeguard systems etc. The physical separation of the systems as regards ventilation as well as by concrete walls rules out the possibility of multiple failures caused by fire, flooding or sabotage. In case od a core-melting accident the specially developed depressurization system reduces primary system pressure to < 20 bar. Various PSA have been conducted resulting in the development of a well-balanced system and component designs and avoiding dominant accident sequences from power and shutdown states.One major feature of the SWR 1000 are the passive safety systems, developed, tested and integrated into the design. They are: Containment cooling condensers for heat removal; Safety Relief Valves; Emergency condensers for heat removal from the RPV; Flooding lines for passive core flooding in the event of a LOCA; Drywell flooding line (core-melt accident). Accidents can be controlled both by active and passive systems. PSA has been also conducted. Some economic aspects are discussed in the paper

  7. Results and present status of the Japan-US collaboration on detector research and development

    International Nuclear Information System (INIS)

    Arai, Yasuo; Takahashi, Kasuke

    1985-02-01

    This is a summary report on the results of the Detector R and D work, which we have been carrying out these three years, under the Japan-U.S. collaboration on High Energy Physics. It is clear that there have been already many considerable progress and outputs in the activities, some of which are already applied to the actual detectors in various ways. It is foreseeable that more extensive development will be realized. It should also be better to emphasize that these detector R and D efforts will be very important for the further development of high energy physics in the near future. (author)

  8. The IAEA Standards for the Radioactive Discharge Control: Present Status and Future Development

    International Nuclear Information System (INIS)

    Balonov, M.; Linsley, G.; Robinson, C.; Cabianca, T.

    2004-01-01

    The International Atomic Energy Agency (IAEA) is the organization within the UN family with a statutory mandate to establish standards for the protection of health and environment against ionizing radiation, and to provide for the application of those standards. As part of these functions, the IAEA periodically reviews the status and continued relevance of the standards to the needs of its Member States. Recent work on the development of standards for the radioactive discharge control includes development of practical guidance for setting discharge limits, elaboration on methodology for the radiation protection of non-human species, and preparation of guidance on environmental monitoring for radiation protection purposes. Development of these safety documents is influenced by recent international and regional tendencies, based on social initiatives, to reduce radioactive discharges substantially below levels justified by radiological criteria. The IAEA has developed preliminary guidance on practical aspects of setting discharge limits, which included a review of national regulatory experience in this regard. This review suggested that societal pressures and regulatory practicalities results in discharge controls that were likely to be more restrictive that those that would be implied by formal optimization techniques. Regulatory review of authorizations includes a number of considerations, including predicted doses to members of the critical group, but the suitability of abatement forms a greater part in the decision-making process than allowed for in previous safety guidance. The IAEA has, in recent years, established a programme of work specifically addressing the development of safety standards on assessing the impact of ionizing radiation on non-human species, in co-operation with other relevant international organizations. The main issues arising will be summarised in the paper with the main focus on an exploration of the possible form of future regulatory

  9. Adult Continuing Education and Human Resource Development: Present Competitors, Potential Partners

    Science.gov (United States)

    Smith, Douglas H.

    2013-01-01

    "Author's Note": In May 1989, this article was published in "Livelong Learning," the monthly practitioner journal of the American Association for Adult and Continuing Education (Vol. 12, No. 7, pp. 13-17). Now viewed as a period reference article, it presents the relationship of adult and continuing education (ACE) and…

  10. Hypoxic Adaptation during Development: Relation to Pattern of Neurological Presentation and Cognitive Disability

    Science.gov (United States)

    Kirkham, Fenella J.; Datta, Avijit K.

    2006-01-01

    Children with acute hypoxic-ischaemic events (e.g. stroke) and chronic neurological conditions associated with hypoxia frequently present to paediatric neurologists. Failure to adapt to hypoxia may be a common pathophysiological pathway linking a number of other conditions of childhood with cognitive deficit. There is evidence that congenital…

  11. Depression therapy optimization at the present stage of development of psychopharmacology

    Directory of Open Access Journals (Sweden)

    Dmitry Sergeyevich Danilov

    2013-01-01

    Full Text Available The paper presents current psychopharmacological approaches to therapy for depressions. It discusses the efficacy of depressants with a monoaminergic mechanism of action. Whether combination therapy with antidepressants and drugs from other pharmacological groups may be used is considered. Separate attention is paid to the agents whose antidepressant effect is unrelated to their action on the monoaminergic system.

  12. The control of non-proliferation of nuclear weapons and nuclear development - present uncertainties

    International Nuclear Information System (INIS)

    Machado de Faria, N.G.; Amaral Barros, E.

    1983-01-01

    This report gives the views of Brazilian lawyers on the non-proliferation of nuclear weapons. It deals with the present situation and future prospects concerning the uses of nuclear energy. In particular, it proposes the preparation of a protocol prohibiting the use of nuclear weapons. (NEA) [fr

  13. Teaching Career Development: A Primer for Instructors and Presenters, Second Edition

    Science.gov (United States)

    Osbor, Debra S.

    2016-01-01

    This second edition not only provides strategies for delivering key components of career development in enthusiastic, innovative, and more meaningful ways, it covers updated standards and new technologies. An entire chapter offers 50+ active learning strategies useful for beginning and intermediate instructors of undergraduate and graduate career…

  14. Past, present and future morphological development of a tsunami-affected coast

    NARCIS (Netherlands)

    Meilianda, Ella

    2009-01-01

    This thesis investigated a thorough geomorphology of Banda Aceh, a coast on the north tip of Sumatra Island, Indonesia which was severely affected by the earthquake and tsunami occurred on 26 December 2004. The response and development of the Banda Aceh coast before and after the tsunami was thus

  15. Chile and Its Efforts to Present High-Level Technologies to the Developed World

    Science.gov (United States)

    Young, Nathan

    2007-01-01

    Chile is rich in natural resources. Like many other resource-dependent nations, it has never made technology transfer a subject of intense focus. This article sheds light on the technological state of Chile today and its efforts to promote development, increase innovation and move towards a knowledge-based economy. The paper summarizes current…

  16. The risk of developing a contact allergy to materials present in diving suits and diving equipment

    Directory of Open Access Journals (Sweden)

    Gadomski Krzysztof

    2017-06-01

    Full Text Available Allergic contact eczema is the most common occupational skin disease caused by allergens. Thus far, no research has been conducted in Poland in relation to the development of contact allergies amongst divers resulting from particular diving suit components. A group of 86 divers were examined using allergy patch tests. Standard products of contact allergy diagnostics were used containing 40 allergens.

  17. The risk of developing a contact allergy to materials present in diving suits and diving equipment

    OpenAIRE

    Gadomski Krzysztof; Siermontowski Piotr; Dąbrowiecki Zbigniew; Olszaski Romuald

    2017-01-01

    Allergic contact eczema is the most common occupational skin disease caused by allergens. Thus far, no research has been conducted in Poland in relation to the development of contact allergies amongst divers resulting from particular diving suit components. A group of 86 divers were examined using allergy patch tests. Standard products of contact allergy diagnostics were used containing 40 allergens.

  18. Developing and Deploying OERs in Sub-Saharan Africa: Building on the Present

    Science.gov (United States)

    Wright, Clayton R.; Reju, Sunday A.

    2012-01-01

    Open educational resources (OERs) have the potential to reduce costs, improve quality, and increase access to educational opportunities. OER development and deployment is one path that could contribute to achieving education for all. This article builds on existing information and communication technology (ICT) implementation plans in Africa and…

  19. Indonesia's present status and needs of human resource development in nuclear field

    International Nuclear Information System (INIS)

    Ruslan, Jeni; Sagala, F.P.

    2000-01-01

    BATAN, started out as a governmental committee established in 1954, has a new organizational structure, based on Presidential Decree of 1998. BATAN has developed its researches in almost practically all-nuclear fields. The situation in Indonesia has been much influenced by the economic crisis, which still being faced by Indonesia. BATAN's strategic planning is described in four areas, those are: 1. Basic human needs, 2. Energy, natural resources and environment, 3. Industry, 4. Socio-cultural and institution. Priority has been given to fulfill, as well as to promote agriculture, health and the industry related to people's welfare, which may develop and improve the immediate needs of the people. In the meantime, we have made considerable investments in manpower development in anticipation of the introduction of nuclear power. BATAN, as of September 1999, has 3889 employees, 26 % of them have bachelor degree, 6 % hold master degrees, and only 2% hold doctoral degree, a total of 34 % employees with university education. Others 11 % have either non-vocational or vocational education beyond High School. The rest of 55 % have high school education or lower, they are administrative clerks (25 %) or technicians (30 %). In the human resources development, BATAN's Education and Training Center, in collaboration with some universities and other national/international institutions, is managing education and training programs for employees. To date, there are 43 BATAN employees studying in various universities in Japan, while another 42 employees are studying in six different countries. Research and Development that have more direct impact to the community will become a priority in the coming years. Without undermining the importance of basic research in advanced fields, we will expect to have more research on application to optimize utilization of research reactors and related facilities for the benefit of both the energy and non-energy sectors. (Tanaka, Y.)

  20. Audit Committee Practice in the Polish Listed Stock Companies. Present Situation and Development Perspectives

    Directory of Open Access Journals (Sweden)

    Piotr Szczepankowski

    2012-06-01

    Full Text Available The audit committee is one of the parts of corporate governance mechanism, which is understood as the relationship between corporate managers, directors and the providers of equity, people and institutions who save and invest their capital to earn the return. This study presents survey research results of audit committee activity in Polish public stock companies quoted on the Warsaw Stock Exchange (WSE. The purpose of this paper is to present the audit committee practice in Poland after 2009. The paper shows that the audit committee practice is still the most problematic issue of transitional Polish corporate governance rules. The survey has shown that the corporate needs and its implementation, and communication with listed companies leave a lot of room for improvement. The paper is based on the documents prepared in 2010 by PricewaterhouseCoopers, the Polish Association of Listed Companies and the Polish Institute of Directors.

  1. Presentation of the 10. European Event on Technology: technologies for a sustainable development; Presentation des 10. Entretiens Europeens de la Technologie: technologies pour un developpement durable

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-11-01

    The European Event on Technology (EET), is a major meeting on technologies, their evolution and their industrial and social implications. In less than a decade, sustainable development has become both an economic and a political priority. It was urgent and legitimate that those who are the mainsprings should take hold of the subject and give it technological content, estimate its costs and define clear timetables. The debates consist of: plenary sessions on environmental, social and economic stakes of sustainable development and the challenges for, and commitment of engineers, managers and politicians with respect to these goals; and workshops, which provide an overview on recently acquired or upcoming technologies developed by sector. These proceedings present several technologies of interest for the energy and environment sectors: Energy efficiency of buildings: towards energy autonomy; superconductors enable in new millennium for electric power industry; advanced gas micro-turbine-driven generator technology; environmental and technical challenges of an offshore wind farm; future nuclear energy system; transports and propulsion systems: modelling combustion in engines: progress and prospects for reducing emissions; on-board computers: reduction in consumption and emissions of engine-transmission units for vehicles; polymer-lithium batteries: perspectives for zero-emission traction; hybrid vehicles and energy/environmental optimization: paths and opportunities; fuel cells and zero-emission: perspectives and developments; urban goods transport: towards a drop in congestion and nuisance; new hybrid propulsion for buses: energy/environmental optimization; Tram-train: city-suburbs concept without transshipment; safety: computerization in controlling nuclear power plant processes (EPR architecture); refractory materials: a key factor for the increase in aero-turbo-engines output; the contribution of waste processing to the production of greenhouse gases; waste as a

  2. Past, present and future of saline lakes: research for global sustainable development

    Science.gov (United States)

    Shadrin, Nickolai; Zheng, Mianping; Oren, Aharon

    2015-11-01

    The 12th International Conference on Salt Lake Research was held in Langfang City, China from July 14 to 18, 2014. Fifteen manuscripts of presentations have been retained for publication in this special issue. They are very diverse, covering the biology, physics, chemistry and geology of salt lakes, the history of hydrological research on the Dead Sea, the effects of socioeconomic and environmental policies by stakeholders on human populations, and the increasing salinization of freshwater lakes around the world.

  3. Present and future developments on the SLAC three-kilometer accelerator

    International Nuclear Information System (INIS)

    Loew, G.A.

    1977-07-01

    A review is given of the innovations which have recently been made or are being planned on the SLAC three-kilometer accelerator. A brief review of overall performance statistics is given, the beam is followed from its origin to the experimental areas. The injector with its new polarized guns, some highlights of klystron research, the SLED or SLAC Energy Development Program, which will boost the electron energy into the 30 to 40 GeV range, and some associated beam loading and beam breakup implications are described. Following these, a brief survey of other microwave developments is given. Some of the innovations being implanted in computer control are summarized, and the changes being planned for the generation and delivery of e +- beams to the PEP ring are discussed

  4. Present capabilities and new developments in antenna modeling with the numerical electromagnetics code NEC

    Energy Technology Data Exchange (ETDEWEB)

    Burke, G.J.

    1988-04-08

    Computer modeling of antennas, since its start in the late 1960's, has become a powerful and widely used tool for antenna design. Computer codes have been developed based on the Method-of-Moments, Geometrical Theory of Diffraction, or integration of Maxwell's equations. Of such tools, the Numerical Electromagnetics Code-Method of Moments (NEC) has become one of the most widely used codes for modeling resonant sized antennas. There are several reasons for this including the systematic updating and extension of its capabilities, extensive user-oriented documentation and accessibility of its developers for user assistance. The result is that there are estimated to be several hundred users of various versions of NEC world wide. 23 refs., 10 figs.

  5. Perspective on present and future alloy development efforts on austenitic stainless steels for fusion application

    Energy Technology Data Exchange (ETDEWEB)

    Maziasz, P.J.

    1984-01-01

    The purpose of this paper is to address important questions concerning how to effect further alloy development of austenitic stainless steels for resistance, and to what extent the behavior of other properties under irradiation, such as strength/embrittlement, fatigue/irradiation creep, corrosion (under irradiation), and radiation-induced activation must be influenced. To summarize current understanding, helium has been found to have major effects on swelling and embrittlement, but several metallurgical avenues are available for significant improvement relative to type 316 stainless steel. Studies on fatigue and irradiation creep, particularly including helium effects, are preliminary but have yet to reveal engineering problems requiring additional alloy development remedies. The effects of irradiation on corrosion behavior are unknown, but higher alloy nickel contents make thermal corrosion in lithium worse. 67 refs. (JDB)

  6. Present and future etiological treatment of bacterial pneumonia 3. The antibacterial drugs under development

    Directory of Open Access Journals (Sweden)

    A.A. Abaturov

    2017-08-01

    Full Text Available The rapid spread of antibiotic-resistant bacterial strains necessitates the development of new antibacterial agents and a review of the guidelines for etiological treatment of bacterial infections, including pneumonia. Currently, new antibacterial agents are being developed that disrupt the biosynthesis of peptidoglycan, teichoic and lipoteichoic acids, and also block the attachment of virulent factors to the bacterial wall. New molecules of old classes of antibiotics and representatives of new classes of antibiotics with their targets (lipid II and III, teichoic and lipoteichoic acids, alanine racemase, and sortase A will become practical tools in clinical practice in the very near future. The goals and mechanisms of action of new antibacterial compounds predetermine their clinical prospects in future strategies for the treatment of infectious bacterial diseases.

  7. Perspective on present and future alloy development efforts on austenitic stainless steels for fusion application

    International Nuclear Information System (INIS)

    Maziasz, P.J.

    1984-01-01

    The purpose of this paper is to address important questions concerning how to effect further alloy development of austenitic stainless steels for resistance, and to what extent the behavior of other properties under irradiation, such as strength/embrittlement, fatigue/irradiation creep, corrosion (under irradiation), and radiation-induced activation must be influenced. To summarize current understanding, helium has been found to have major effects on swelling and embrittlement, but several metallurgical avenues are available for significant improvement relative to type 316 stainless steel. Studies on fatigue and irradiation creep, particularly including helium effects, are preliminary but have yet to reveal engineering problems requiring additional alloy development remedies. The effects of irradiation on corrosion behavior are unknown, but higher alloy nickel contents make thermal corrosion in lithium worse. 67 refs

  8. Present status of study on development of materials resistant to radiation and beam impact

    International Nuclear Information System (INIS)

    Kawai, M.; Kokawa, H.; Michiuchi, M.; Kurisihita, H.; Goto, T.; Futakawa, M.; Yoshiie, T.; Hasegawa, A.; Watanabe, S.; Yamamura, T.; Hara, N.; Kawasaki, A.; Kikuchi, K.

    2008-01-01

    Pulsed spallation neutron sources for the materials structure science are severely influenced by beam impact and radiation damage. We have developed the materials strong to these influence since 2004. In this paper, recent topics are described concerning the development of intergranular corrosion (IGC)-resistant austenitic stainless steel for target vessel and window, radiation-resistant ultra-fine grained tungsten materials (W-TiC) for a solid target, CrN film on a tungsten target by means of a molten-salt method, surface treatment of stainless steel for pitting damage in mercury target. Bubble behavior at the interface of mercury and window glass was also observed to clarify the phenomenon of the pitting damage

  9. Present status and future program of HTR-research and development in Switzerland

    International Nuclear Information System (INIS)

    Sarlos, G.; Bucher, K.H.

    1990-01-01

    Research, Development and Design of Gas-cooled Reactors have already a long and well accepted tradition in Switzerland. These activities began with the design and construction of an experimental gas-cooled power station of 30 MW by the Swiss industry in the early sixties. Swiss industry restricted themselves to the development and the supply of reactor systems and components only. Through extensive research and the participation in various international projects such as AGR, AVR, FSV, THTR, HHT, HTR etc., it was possible to gain valuable know-how, which qualified the Swiss industry as reliable manufactures of reactor components and enabled them to render all kinds of engineering services for nuclear power plants. In order to utilize the existing vast experience, the companies concerned and the PSI agreed in 1979 to join as partners and established the 'Swiss Community for the Development of Nuclear Technology' called IGNT. Partners of IGNT are ABB, Baden; Sulzer, Winterthur; B + G, Lausanne; EWI, Zuerich; Colenco, Baden; and the Swiss Federal Institute for Reactor Research (PSI). IGNT represents and coordinates the activities of the partners, especially in the field of the high temperature gas-cooled reactors. As a consequence of this partnership, the members of IGNT engaged themselves in the development of the HTR-Technology in general and particularly in the design of the HTR-500. Another project which was pursued in Switzerland over the recent years, is the gascooled heating reactor, a small pebble-bed HTR of 10 to 20 MW for district heating purposes. In 1988 work on this project has been terminated for political reasons, but will probably be taken up in 1990/91. (author)

  10. Present status and history of nuclear data development for transmutation technology

    CERN Document Server

    Hasegawa, A

    2002-01-01

    A history of development of nuclear data from JENDL (Japanese Evaluated Nuclear Data Library)-1 to JENDL-3.3 and JENDL-HF (High energy File) and JENDL- Actinide File are stated. 5 nuclear data such as JENDL-1, JENDL-2, JENDL-3.1, JENDL-3.2 and JENDL-3.3 have been developed by JAERI. JENDL-1 for fast reactor (1977) has 66+6 nuclide and 15 MeV the largest energy. JENDL-2 for fast and light water reactor (1982) has 173+8 nuclide and 20 MeV. All-purpose nuclear data: JENDL-3.1 (1990) with 305+19 nuclide and 59 2nd gamma-ray data, JENDL-3.2 (1994) with 318+22 nuclide and 66 2nd gamma-ray data and JENDL-3.3 (2002) with 335+2 nuclide, 114 2nd gamma-ray data, 60 angular dependence neutron data and 20 MeV have been developed. JENDL-3.3 was opened at JAERI home page in May 2002. JENDL High Energy library consists of JENDL-HF, JENDL-Photonuclear Data File and JENDL-PKA/KERMA File. JENDL-HF includes nuclear reaction data of neutron and proton incidence, for example, total cross section, elastic scattering cross section a...

  11. Towards new developments in uranium chemistry. Scientific report presented to obtain and Accreditation to Supervise Research

    International Nuclear Information System (INIS)

    Berthet, Jean-Claude

    2003-01-01

    After a presentation of his academic curriculum, the author proposes an overview of some of his main research activities and works which notably addressed the reactivity of uranium III complexes (synthesis and reactivity of uranium hydride complexes, synthesis of poly-metallic complexes), amide complexes (synthesis of uranium IV amide precursors, reactivity of cationic complexes, synthesis of uranium IV complexes), uranium triflate (or trifluoromethanesulfonate) complexes, the synthesis of U(Cot)X 2 (L) n complexes and of their derivatives, the complexing of lanthanide iodides and triflates

  12. Present status on development of industrial radiation process plants in Brazil

    International Nuclear Information System (INIS)

    Rela, Paulo Roberto; Sampa, Maria Helena O.

    2005-01-01

    Nowadays there is a big effort from industry and agribusiness community to aggregate value to the products manufactured in the country in order to become competitive in the international market. The irradiation processing have being extensively applied as effective and reliable technique for the sterilization for medical care products and the reduction of bioburden in food ingredients. For other materials and process production this technique already is competitive and environmentally friendly. Works are being concentrated by the research institutes driving the efforts on becoming available and spreading the results of their investigations and developing irradiation facilities approaching the industry and agribusiness to include the irradiation process in production chain. (author)

  13. The present state and future development of X-ray imaging technology

    International Nuclear Information System (INIS)

    Gou Liang; Wang Xuben; Cao Hui

    2002-01-01

    Medical imaging has long been the hot topic of clinical medical sciences, the X-ray imaging equipment is a popular device of current medical imaging, and the digital imaging technology has become a challenge to the conventional plane imaging. The author first discusses that the key of X-ray-based imaging is the generator and detector of X-ray and the improvement of imaging software, and then points out that the future development of medical imaging will aim at the capability of reducing radiation and handling more efficient and accurate data capacity

  14. Present status and future prospect of coated conductor development and its application in Japan

    Science.gov (United States)

    Shiohara, Y.; Yoshizumi, M.; Izumi, T.; Yamada, Y.

    2008-03-01

    The current national project on coated conductors using Y-system superconductors has been carried out over the project period (FY2003-FY2007). In this paper, the current status and the future prospect of this project are reviewed. The high performance tape development group, consisting of Fujikura and SRL-NCCC, has worked on the tape by PLD-REBCO superconducting layers on PLD-CeO2/IBAD-GZO buffered substrates. A high product of Ic and L, higher than 112 166 A m, was achieved in a 368 m-304.8 A GdBCO tape whose Ic value is mostly above 350 A/cm in width. The performance under magnetic field was also improved up to 42 A at 3 T in a GdBCO short film with doping of ZrO2. 61 m long GdBCO tape with ZrO2 doping showed a high Ic value of 220 A at self field and 30 A at 3 T. On the other hand, another group focusing on low production cost has worked on TFA-MOD and MOCVD processes. The extremely high Ic value of 735 A/cm-w was obtained in TFA-MOD films on PLD-CeO2/IBAD-GZO/Hastelloy substrate due to the effect of Ba-poor nominal composition. In efforts towards long tape production by the SWCC group, a 200 m long tape with a high Ic value of 200 A/cm-w was obtained using a batch-type furnace. The Ic × L value of this tape was 40 000 A m, which is the highest value in the world obtained by the TFA-MOD process. Based on the above achievements in coated conductor process development, two new additional goals were set in the project. One is the development of extremely low cost tape and the other is the development of the basic technologies for making electric power devices of cables, transformers, motors, current-limiters and cryocoolers. Some of the new investigations have already revealed marvellous results, such as a 15 kW motor, low AC loss coils, low AC loss cables, etc.

  15. Present status of exploration and development of the geothermal resources of Guatemala

    International Nuclear Information System (INIS)

    Caicedo, A.; Palma, J.

    1990-01-01

    This paper reports on the study of geothermal exploration and geothermal development in the nation of Guatemala that is being led by the Instituto Nacionai de electrificacion (INDE) through the Unidad de Desarrollo Geotermico (UDG), for the purpose of developing the geothermal resources in order to generate electricity. Since 1972, it has accomplished geoscientific studies with regional surveys in 13 areas located in the volcanic region in the southern part of the country. Also, prefeasibility studies have been carried out in geothermal areas such as Moyuta and Tecuamburro in the southeast of the country; Amatitlan in the central region and San Marcos in the west. Moreover, in the geothermal field of Zunil I, which is located in the western Department of Quetzaltenango, the feasibility study has been completed, and the first geothermo-electric plant of 15 MW is being schedule for June of 1993. By then, the feasibility study for the second power plant in the more promising area of Zunil II located on the outskirts of Zunil I or Amatitlan. Also, in the area of Zunil I a farm-produce dehydration plant has been built through a technical cooperation agreement between INDE and Los Alamos National Laboratory, LANL. It has the purpose of showing the use of direct-heat through produced steam from the slim hole Z-11

  16. GSK3 Inhibitors in the Therapeutic Development of Diabetes, Cancer and Neurodegeneration: Past, Present and Future.

    Science.gov (United States)

    Maqbool, Mudasir; Hoda, Nasimul

    2017-11-16

    GSK3 has gained a considerable attention of researchers in the late 1970s as an inevitable drug target to treat diabetes. Furthermore, it was found to have a key role in the development of diseases like cancer and neurodegeneration (ND). A broad spectrum of GSK3 inhibitors have been discovered from time to time in order to curb these diseases. Inhibition of GSK3 by insulin boosts the dephosphorylation of glycogen synthase, hence its activation to convert UDP glucose into glycogen. Lack of insulin and insulin-resistance is supposed to be the cause of type 2 diabetes (Diabetes mellitus). Additionally, GSK3 stabilizes the components of beta-catenin complex, hence promotes oncogenesis. Phosphorylation of GSK3 by Akt and some other kinases also favours the carcinogenesis. However, in some cases GSK3 has tumor supressing character. GSK3 has been found to have a prominent role in the formation of amyloid plaques and neurofibrillary tangles (abnormal protein accumulations) which are the main suspects of Alzheimer's disease (AD). GSK3 inhibitors have been reported to have amyloidbeta disaggregation property and have been found to promote the adult hippocampal neurogenesis in vivo as well as in vitro. This manuscript thoroughly reviews the involvement of GSK3 in diabetes, cancer and ND. Furthermore, development of GSK3 inhibitors as antidiabetes, anticancer and antineurodegenerative agents focusing mainly on lead optimization has been discussed. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

  17. Development of Primer Pairs from Molecular Typing of Rabies Virus Variants Present in Mexico

    Directory of Open Access Journals (Sweden)

    Fernando Bastida-González

    2016-01-01

    Full Text Available Nucleoprotein (N gene from rabies virus (RABV is a useful sequence target for variant studies. Several specific RABV variants have been characterized in different mammalian hosts such as skunk, dog, and bats by using anti-nucleocapsid monoclonal antibodies (MAbs via indirect fluorescent antibody (IFA test, a technique not available in many laboratories in Mexico. In the present study, a total of 158 sequences of N gene from RABV were used to design eight pairs of primers (four external and four internal primers, for typing four different RABV variants (dog, skunk, vampire bat, and nonhematophagous bat which are most common in Mexico. The results indicate that the primer and the typing variant from the brain samples, submitted to nested and/or real-time PCR, are in agreement in all four singleplex reactions, and the designed primer pairs are an alternative for use in specific variant RABV typing.

  18. International Conference on Human Resource Development for Nuclear Power Programmes: Building and Sustaining Capacity. Presentations

    International Nuclear Information System (INIS)

    2014-01-01

    The objectives of the conference are to: • Review developments in the global status of HRD since the 2010 international conference; • Emphasize the role of human resources and capacity building programmes at the national and organizational level for achieving safe, secure and sustainable nuclear power programmes; • Discuss the importance of building competence in nuclear safety and security; • Provide a forum for information exchange on national, as well as international, policies and practices; • Share key elements and best practices related to the experience of Member States that are introducing, operating or expanding nuclear power programmes; • Highlight the practices and issues regarding HRD at the organizational and national level; • Highlight education and training programmes and practices; • Emphasize the role of nuclear knowledge management for knowledge transfer and HRD; and • Elaborate on the role and scope of various knowledge networks

  19. Novel Scanning Lens Instrument for Evaluating Fresnel Lens Performance: Equipment Development and Initial Results (Presentation)

    Energy Technology Data Exchange (ETDEWEB)

    Herrero, R.; Miller, D. C.; Kurtz, S. R.; Anton, I.; Sala, G.

    2013-07-01

    A system dedicated to the optical transmittance characterization of Fresnel lenses has been developed at NREL, in collaboration with the UPM. The system quantifies the optical efficiency of the lens by generating a performance map. The shape of the focused spot may also be analyzed to understand change in the lens performance. The primary instrument components (lasers and CCD detector) have been characterized to confirm their capability for performing optical transmittance measurements. Measurements performed on SoG and PMMA lenses subject to a variety of indoor conditions (e.g., UV and damp heat) identified differences in the optical efficiency of the evaluated lenses, demonstrating the ability of the Scanning Lens Instrument (SLI) to distinguish between the aged lenses.

  20. Present status of plasma-wall interactions research and materials development activities in the US

    International Nuclear Information System (INIS)

    Hirooka, Y.; Conn, R.W.

    1989-08-01

    It is well known in the fusion engineering community that the plasma confinement performance in magnetic fusion devices is strongly affected by edge-plasma interactions with surface components. These plasma-material interactions (PMI) include fuel particle recycling and impurity generation both during normal and off-normal operation. To understand and then to control PMI effects, considerable effort has been made, particularly over the last decade in US, supported by Department of Energy, Division of Development and Technology. Also, because plasma-facing components are generally expected to receive significant amount of heat due to plasma bombardment and run-away electrons, materials must tolerate high-heat fluxes (HHF). The HHF-component research has been conducted in parallel with PMI research. One strong motivation for these research activities is that DT-burning experiments are currently planned in the Tokamak Test Fusion Reactor (TFTR) in early 1990s. Several different but mutually complementary approaches have been taken in the PMI+HHF research. The first approach is to conduct PMI experiments using toroidal fusion devices such as TFTR. The second one is to simulate elemental processes involved in PMI using ion beams and electron beams, etc. The last one but not least is to use non-tokamak plasma facilities. Along with these laboratory activities, new materials have been developed and evaluated from the PMI+HHF point of view. In this paper, several major PMI+HHF research facilities in US and their activities are briefly reviewed. 21 refs., 10 figs., 2 tabs

  1. Age interactions in the development of naturally acquired immunity to Plasmodium falciparum and its clinical presentation.

    Directory of Open Access Journals (Sweden)

    John J Aponte

    2007-07-01

    Full Text Available BACKGROUND: Naturally acquired malaria immunity has many determinants and, in the absence of immunological markers of protection, studies assessing malaria incidence through clinical endpoints remain an approach to defining immunity acquisition. We investigated the role of age in disease incidence and the effects of chemoprophylaxis on clinical immunity development to Plasmodium falciparum during a randomised controlled trial. METHODS AND FINDINGS: A total of 415 Tanzanian infants were randomly assigned to receive weekly malaria prophylaxis with Deltaprim (3.125 mg of pyrimethamine plus 25 mg of dapsone or placebo between the ages of 2 and 12 mo. Children were followed up until 4 y of age. Uncomplicated febrile malaria, severe malaria, and anaemia morbidity were assessed through hospital-based passive surveillance. Compared with the group of control participants, there was a marked reduction in the incidence of clinical malaria, severe malaria, and anaemia in the group of children who had received chemoprophylaxis during the first year of life. After discontinuing the intervention, there was a significant increase in the incidence of clinical malaria for 2 y. The cumulative rates of clinical malaria, by age 4 y, were slightly higher in the group of children who had previously received chemoprophylaxis: 3.22 episodes versus 3.02 episodes in the group of control participants; rate difference 0.20 (95% confidence interval [CI]: -0.21 to 0.59. By age 4 y, the cumulative rates of severe malaria, however, were slightly lower in chemosuppressed children (0.47 versus 0.59 (rate difference -0.12 [95% CI: -0.27 to 0.03]. The number of episodes of anaemia was also slightly lower in chemosuppressed children by age 4 y: 0.93 episodes (95% CI: 0.79 to 0.97 versus 1.12 episodes in the group of control participants (95% CI: 0.97 to 1.28 (rate difference -0.19 [95% CI: -0.40 to 0.01], respectively. CONCLUSIONS: Reducing exposure to P. falciparum antigens through

  2. [Follow-up of patients with inflammatory bowel disease: developments presented at Digestive Disease Week 2014].

    Science.gov (United States)

    García-López, Santiago

    2014-09-01

    A lot of data were reported about monitoring patients with inflammatory bowel disease, with varying degrees of practical applicability. Concerning the evaluation of disease activity, it was established that objective assessments are needed. Among the techniques that we use, although endoscopy is undoubtedly the reference standard, a lot of data were presented regarding less invasive techniques. The importance of MRIs, CTs and ultrasounds (with some variations) was thus reiterated. The importance of fecal calprotectin is also reiterated, not only for colon disease, but probably small intestine disease as well. Regarding treatment monitoring, a great deal was reported about anti-TNF therapy, demonstrating again its potential role when properly used. In addition to results with infliximab, results with adalimumab were reported as very consistent. For colon cancer prevention, it seems that the clinical guidelines are achieving their objective. It also seems clear that we must improve conventional endoscopic techniques. Finally, there are other aspects that need to be considered when monitoring our patients, such as adequate sleeping patterns, anxiety or depression. Copyright © 2014 Elsevier España, S.L.U. All rights reserved.

  3. Present developments of research MeV Pelletron ion implantation systems

    Science.gov (United States)

    Norton, G. A.; Daniel, R. E.; Loger, R. L.; Schroeder, J. B.

    1989-02-01

    National Electrostatics Corp. has manufactured 79 ion beam systems. 17 of these Pelletron systems were designed with MeV ion implantation capability as a primary objective. Of these system, 8 were designed specifically for production ion implantation with a maximum beam energy of 4 MeV. For research applications, ion beam masses from carbon through gold have been accelerated with a maximum observed energy of 38 MeV from a 3 MV tandem S-series Pelletron. This paper will present performance charts which describe the observed ion beam capabilities of existing 3 MV tandem Pelletrons. In addition, the performance of the new high current, four charging chain, S-Series accelerator, currently in manufacture, will be given. A new 4 MV tandem S-Series Pelletron has been proposed, its expected capabilities will be stated. The NEC electrostatics raster scanner which is in use for MeV implantation provides uniform deposition at a maximum scan angle of ± 3.0 ° for 4 MeV doubly charged ions. The output wave form at ±10 kV scanning potential will be shown.

  4. Development of an add-on kit for scanning confocal microscopy (Conference Presentation)

    Science.gov (United States)

    Guo, Kaikai; Zheng, Guoan

    2017-03-01

    Scanning confocal microscopy is a standard choice for many fluorescence imaging applications in basic biomedical research. It is able to produce optically sectioned images and provide acquisition versatility to address many samples and application demands. However, scanning a focused point across the specimen limits the speed of image acquisition. As a result, scanning confocal microscope only works well with stationary samples. Researchers have performed parallel confocal scanning using digital-micromirror-device (DMD), which was used to project a scanning multi-point pattern across the sample. The DMD based parallel confocal systems increase the imaging speed while maintaining the optical sectioning ability. In this paper, we report the development of an add-on kit for high-speed and low-cost confocal microscopy. By adapting this add-on kit to an existing regular microscope, one can convert it into a confocal microscope without significant hardware modifications. Compared with current DMD-based implementations, the reported approach is able to recover multiple layers along the z axis simultaneously. It may find applications in wafer inspection and 3D metrology of semiconductor circuit. The dissemination of the proposed add-on kit under $1000 budget could also lead to new types of experimental designs for biological research labs, e.g., cytology analysis in cell culture experiments, genetic studies on multicellular organisms, pharmaceutical drug profiling, RNA interference studies, investigation of microbial communities in environmental systems, and etc.

  5. The present stage of development of ionizing radiation treatment in France

    International Nuclear Information System (INIS)

    Henon, Y.

    1985-03-01

    In 1982, the three Committees (FAO, IAEA, WHO) in charge of examining the documentation relating to applications for authorization reacted favourably to the summary report on the toxicology of irradiated foodstuffs submitted by the CEA. New applications need no longer contain a new toxicological study if the dose is lower than 10 kGy. This liberalization of procedure has encouraged industrialists to prepare application documentations. Technically convincing but economically disappointing experiments have shown that the two existing radiation sterilization facilities are unsuitable for harvested agricultural products. It is therefore advisable to set up units which could meet the requirements of the food industry. In the Marseille region it is planned to build a multipurpose commercial facility and a development facility by 1986. Moreover, a firm in Western France is reported soon to be acquiring an electron accelerator for the radicidation of mechanically pointed and frozen poultry. Concurrently with these activities a large information campaign has been undertaken. However, it is too early to offer to the public products for large-scale human consumption which have been treated with ionizing radiation [fr

  6. Leaf venation: structure, function, development, evolution, ecology and applications in the past, present and future.

    Science.gov (United States)

    Sack, Lawren; Scoffoni, Christine

    2013-06-01

    The design and function of leaf venation are important to plant performance, with key implications for the distribution and productivity of ecosystems, and applications in paleobiology, agriculture and technology. We synthesize classical concepts and the recent literature on a wide range of aspects of leaf venation. We describe 10 major structural features that contribute to multiple key functions, and scale up to leaf and plant performance. We describe the development and plasticity of leaf venation and its adaptation across environments globally, and a new global data compilation indicating trends relating vein length per unit area to climate, growth form and habitat worldwide. We synthesize the evolution of vein traits in the major plant lineages throughout paleohistory, highlighting the multiple origins of individual traits. We summarize the strikingly diverse current applications of leaf vein research in multiple fields of science and industry. A unified core understanding will enable an increasing range of plant biologists to incorporate leaf venation into their research. © 2013 The Authors New Phytologist © 2013 New Phytologist Trust.

  7. Recent developments in wireless recording from the nervous system with ultrasonic neural dust (Conference Presentation)

    Science.gov (United States)

    Maharbiz, Michel M.

    2017-05-01

    The emerging field of bioelectronic medicine seeks methods for deciphering and modulating electrophysiological activity in the body to attain therapeutic effects at target organs. Current approaches to interfacing with peripheral nerves and muscles rely heavily on wires, creating problems for chronic use, while emerging wireless approaches lack the size scalability necessary to interrogate small-diameter nerves. Furthermore, conventional electrode-based technologies lack the capability to record from nerves with high spatial resolution or to record independently from many discrete sites within a nerve bundle. We recently demonstrated (Seo et al., arXiV, 2013; Seo et al., Neuron, 2016) "neural dust," a wireless and scalable ultrasonic backscatter system for powering and communicating with implanted bioelectronics. There, we showed that ultrasound is effective at delivering power to mm-scale devices in tissue; likewise, passive, battery-less communication using backscatter enabled high-fidelity transmission of electromyogram (EMG) and electroneurogram (ENG) signals from anesthetized rats. In this talk, I will review recent developments from my group and collaborators in this area.

  8. Record linkage: development and present state of the art in Canada

    International Nuclear Information System (INIS)

    Newcombe, H.B.

    1979-11-01

    If one wants to know whether something is good or bad for people, in the long run, there is only one way to be sure. This is to follow up those who have tried it, and those who have not, to see what has happened to them. For people exposed to agents suspected of causing cancer, the follow-up period may be a number of decades, and this often creates difficulities in carrying out appropriate studies using conventional methods. Today, however, computer techniques make it possible to search rapidly for the death records and cancer records pertaining to very large study populations that are believed to be Σat riskΣ because of exposures to suspected carcinogens, received for example in the workplace or as a result of medical diagnostic and treatment procedures. All that is required is adequate personal identifying information, in conjunction with the exposure data. Without this, however, the risks may never be detected, and quantified, unless they are very large, and protective measures may never be instituted. The development, in Canada, of the computuer procedures and record files for such work, will be reviewed. Future trends in these matters should result in earlier detection of even small risks from carcinogens in the workplace and elsewhere. Large-scale cancer epidemioloy is already technically feasible and, wherever the public and those at risk want it, it can be carried out under conditions which carefuuly guard the privacy of the individual. (auth)

  9. Radionuclide ventriculography (equilibrium gated blood pool scanning) - its present clinical position and recent developments

    International Nuclear Information System (INIS)

    Adam, W.E.; Clausen, M.; Hellwig, D.; Henze, E.; Bitter, F.

    1988-01-01

    Myocardial scanning (MS) and radionuclide ventriculography (RNV) aim in two completely different directions: RNV tries to image heart motion, that is, mechanical (pump) function, and therefore belongs to the group of first-order functional imaging (FI, imaging mechanical function), whereas MS is based on myocardial metabolism, and therefore can be attributed to third-order functional imaging (metabolism). This statement is relevant for the assessment of the clinical position of RNV: Third-order (metabolism) functional imaging is the domain of nuclear medicine (NM), whereas first-order FI has to face the competition of alternative noninvasive procedures such as ultrasound (US), digital subtraction angiography (DSA), computer tomography (CT), and nuclear magnetic resonance (NMR). The domain of RNV includes stages two (acute infarction) and three (postinfarction period) of coronary arterial disease (CAD). The advantageous combination of quantitative data on global, left ventricular (LV) function and imaging of regional motion ensures the superiority of RNV over US. However, RNV is inferior to MS in physical examinations in the preinfarction stage of CAD, whereas US is clearly inferior to both NM procedures. Recent progress could be attained by gated SPECT (GASPECT). A proposal is presented for simplification of this time-consuming procedure. Technetium-labeled isonitriles offer the chance for the combination of 'perfusion-motion' imaging of the myocardium. However, even standard RNV offers new possibilities. The multitude of parameters produced by quantitation has not yet been exploited completely. This can be done by discriminant analysis. The computer finds out an optimal subset from the whole set of parameters for the solution of a significant clinical problem. The software 'learns' to find the 'label' of a special pathognomonic entity. This computer work is supported by a relational data bank (Oracle) and an optical disk. (orig./MG)

  10. NASA Crew and Cargo Launch Vehicle Development Approach Builds on Lessons from Past and Present Missions

    Science.gov (United States)

    Dumbacher, Daniel L.

    2006-01-01

    The United States (US) Vision for Space Exploration, announced in January 2004, outlines the National Aeronautics and Space Administration's (NASA) strategic goals and objectives, including retiring the Space Shuttle and replacing it with new space transportation systems for missions to the Moon, Mars, and beyond. The Crew Exploration Vehicle (CEV) that the new human-rated Crew Launch Vehicle (CLV) lofts into space early next decade will initially ferry astronauts to the International Space Station (ISS) Toward the end of the next decade, a heavy-lift Cargo Launch Vehicle (CaLV) will deliver the Earth Departure Stage (EDS) carrying the Lunar Surface Access Module (LSAM) to low-Earth orbit (LEO), where it will rendezvous with the CEV launched on the CLV and return astronauts to the Moon for the first time in over 30 years. This paper outlines how NASA is building these new space transportation systems on a foundation of legacy technical and management knowledge, using extensive experience gained from past and ongoing launch vehicle programs to maximize its design and development approach, with the objective of reducing total life cycle costs through operational efficiencies such as hardware commonality. For example, the CLV in-line configuration is composed of a 5-segment Reusable Solid Rocket Booster (RSRB), which is an upgrade of the current Space Shuttle 4- segment RSRB, and a new upper stage powered by the liquid oxygen/liquid hydrogen (LOX/LH2) J-2X engine, which is an evolution of the J-2 engine that powered the Apollo Program s Saturn V second and third stages in the 1960s and 1970s. The CaLV configuration consists of a propulsion system composed of two 5-segment RSRBs and a 33- foot core stage that will provide the LOX/LED needed for five commercially available RS-68 main engines. The J-2X also will power the EDS. The Exploration Launch Projects, managed by the Exploration Launch Office located at NASA's Marshall Space Flight Center, is leading the design

  11. Development of a radioimmunological method to determine E and Fα prostaglandins present in the urine

    International Nuclear Information System (INIS)

    Benzoni, Daniel.

    1979-05-01

    A radioimmunological method of PGE and PGFα determination has been developed to evaluate their elimination in the urine, one of the best representations of their renal synthesis. The urine is collected for 24 hours at 4 0 C then frozen to -20 0 C until the moment of analysis, which includes a preliminary extraction and chromatographic separation stage. The overall extraction and chromatographic yields are: - 78.7%+-74 (SD) for PGE (n=394) -89%+-4.1 (SD) for PGFα (n=119). The antigen-antibody reaction takes place in PBS-G pH 7.4 buffer under a final volume of 300 μl; incubation proceeds at 4 0 C for 24 hours in the presence of 4.8 pg tritiated PGE 2 or 5.4 pg tritiated PGF 2 α. Immune serum are obtained by immunisation of rabbits with a PG-bovine serumalbumin combination coupled by a carbodiimide. Those used here have an affinity constant and a sensitivity equal respectively to: - 3,7 10 10 l.mole -1 and 1,1 pg for the anti PGE immune serum adopted, - 3,1 10 10 l.mole -1 and 0,9 pg for the anti PGFα immune serum adopted. In view of non-specific interferences due to the organic solvents required for extraction and chromatography the overall sensitivity of the system should be taken as: - 2.2 pg for PGE, - 1.8 pg for PGFα. The intra and intertest reproducibilities are respectively: - 5.6% and 7.8% for PGE, 2.7% and 8.6% for PGFα [fr

  12. The present, past and future of the study of intellectual disability: challenges in developing countries.

    Science.gov (United States)

    Parmenter, Trevor R

    2008-01-01

    There is strong evidence that socio-cultural factors largely determine what is seen as competent behaviour. Within western high income countries, driven by the values of utilitarian individualism, the construct of intellectual disability has been largely determined to meet the needs of urban, industrialised societies. In contrast, competence in non-industrialised societies may be more reflected in collaborative, interpersonal problem solving skills such as those found among Nigerian students labelled as intellectually disabled. However, people who are judged to be incompetent or "obtrusive" in countries deficient in support services, are often neglected and consigned to a life in poorly managed segregated institutions, as is the case in China, Russia and some countries in Eastern Europe. Non western countries that have a long history of a globalised economy, such as Taiwan and Japan also remain committed to segregated institutional provisions for people with an intellectual disability, despite a notional acceptance of inclusionary policies enunciated by the United Nations Declarations and Conventions. In this paper is concluded that it must be recognised that the population of people with an intellectual disability, regardless of how the condition is defined and classified, is quite heterogeneous. Their needs are also varied and not at all dissimilar to those of the general population. As developing countries adopt western style consumer-driven economies, there is an extreme danger that they, too, will follow the same trajectory of exclusion and impose the culture of "otherness" for a group whose contribution to that society will be devalued. Good science is futile unless it benefits all peoples.

  13. Array-CGH analysis in Rwandan patients presenting development delay/intellectual disability with multiple congenital anomalies.

    Science.gov (United States)

    Uwineza, Annette; Caberg, Jean-Hubert; Hitayezu, Janvier; Hellin, Anne Cecile; Jamar, Mauricette; Dideberg, Vinciane; Rusingiza, Emmanuel K; Bours, Vincent; Mutesa, Leon

    2014-07-12

    Array-CGH is considered as the first-tier investigation used to identify copy number variations. Right now, there is no available data about the genetic etiology of patients with development delay/intellectual disability and congenital malformation in East Africa. Array comparative genomic hybridization was performed in 50 Rwandan patients with development delay/intellectual disability and multiple congenital abnormalities, using the Agilent's 180 K microarray platform. Fourteen patients (28%) had a global development delay whereas 36 (72%) patients presented intellectual disability. All patients presented multiple congenital abnormalities. Clinically significant copy number variations were found in 13 patients (26%). Size of CNVs ranged from 0,9 Mb to 34 Mb. Six patients had CNVs associated with known syndromes, whereas 7 patients presented rare genomic imbalances. This study showed that CNVs are present in African population and show the importance to implement genetic testing in East-African countries.

  14. Proceeding of the Fifth Scientific Presentation on Nuclear Fuel Cycle: Development of Nuclear Fuel Cycle Technology in Third Millennium

    International Nuclear Information System (INIS)

    Suripto, A.; Sastratenaya, A.S.; Sutarno, D.

    2000-01-01

    The proceeding contains papers presented in the Fifth Scientific Presentation on Nuclear Fuel Element Cycle with theme of Development of Nuclear Fuel Cycle Technology in Third Millennium, held on 22 February in Jakarta, Indonesia. These papers were divided by three groups that are technology of exploration, processing, purification and analysis of nuclear materials; technology of nuclear fuel elements and structures; and technology of waste management, safety and management of nuclear fuel cycle. There are 35 papers indexed individually. (id)

  15. Embryonic Testicular Regression Syndrome Presenting as Primary Amenorrhea: A Case Report and Review of Disorders of Sexual Development.

    Science.gov (United States)

    Hunter, J D; Pierce, S R; Calikoglu, A S; Howell, J O

    2016-08-01

    Sex development depends on the synchronous interaction of complicated genetic and hormonal events. Sex differentiation begins with sex determination, which is the assignment of the embryonic bipotential gonads as either testes or ovaries on the basis of transcriptional regulation. Hormonal regulation then directs the development of the male or female phenotype. Disruptions of this intricate cascade of events result in disorders of sexual development. A 16-year-old female adolescent presented with primary amenorrhea. Evaluation revealed female external genitalia, XY karyotype, absent gonadal tissue, and rudimentary Müllerian structures. On the basis of her constellation of findings, the most logical diagnosis was the rare embryonic testicular regression syndrome. A careful understanding of embryonic sexual development is critical to the evaluation of patients with disorders of sexual development. Copyright © 2016 North American Society for Pediatric and Adolescent Gynecology. Published by Elsevier Inc. All rights reserved.

  16. Food in Relation to Sustainable Development Expressed in Swedish Syllabuses of Home and Consumer Studies: At Present and Past

    Science.gov (United States)

    Gisslevik, Emmalee; Wernersson, Inga; Åberg, Helena; Larsson, Christel

    2016-01-01

    Little is known what the term sustainable development entails in relation to the school subject of home and consumer studies and the subject's knowledge area of food. The aim is to illustrate how food is expressed in national syllabuses of home and consumer studies at present and in the past, and its operationalization into sustainable…

  17. Recent Developments in the Numerics of Nonlinear Hyperbolic Conservation Laws : Lectures Presented at a Workshop at the Mathematical Research Institute

    CERN Document Server

    Bijl, Hester; Meister, Andreas; Sonar, Thomas

    2013-01-01

    In January 2012 an Oberwolfach workshop took place on the topic of  recent developments in the numerics of partial differential equations. Focus was  laid on methods of high order and on applications in Computational Fluid Dynamics. The book covers most of the talks presented at this workshop.  

  18. Array-CGH analysis in Rwandan patients presenting development delay/intellectual disability with multiple congenital anomalies

    Science.gov (United States)

    2014-01-01

    Background Array-CGH is considered as the first-tier investigation used to identify copy number variations. Right now, there is no available data about the genetic etiology of patients with development delay/intellectual disability and congenital malformation in East Africa. Methods Array comparative genomic hybridization was performed in 50 Rwandan patients with development delay/intellectual disability and multiple congenital abnormalities, using the Agilent’s 180 K microarray platform. Results Fourteen patients (28%) had a global development delay whereas 36 (72%) patients presented intellectual disability. All patients presented multiple congenital abnormalities. Clinically significant copy number variations were found in 13 patients (26%). Size of CNVs ranged from 0,9 Mb to 34 Mb. Six patients had CNVs associated with known syndromes, whereas 7 patients presented rare genomic imbalances. Conclusion This study showed that CNVs are present in African population and show the importance to implement genetic testing in East-African countries. PMID:25016475

  19. Development and present status of the Russian-German soft X-ray beamline at BESSY II

    International Nuclear Information System (INIS)

    Fedoseenko, S.I.; Iossifov, I.E.; Gorovikov, S.A.; Schmidt, J.-S.; Follath, R.; Molodtsov, S.L.; Adamchuk, V.K.; Kaindl, G.

    2001-01-01

    We report on further developments of the optical design of the Russian-German soft X-ray beamline at BESSY II. Ray-tracing calculations reveal state-of-the-art characteristics of the modified layout. Resolving power up to 25 000 and photon flux up to 3x10 10 photons/s/100 mA will be available for spectroscopic experiments. Technical details of operation of the precision mechanics used for fine adjustment of the first mirror are presented

  20. CATCHY PRESENTATIONS

    DEFF Research Database (Denmark)

    Eriksen, Kaare; Tollestrup, Christian; Ovesen, Nis

    2011-01-01

    An important competence for designers is the ability to communicate and present ideas and proposals for customers, partners, investors and colleagues. The Pecha Kucha principle, developed by Astrid Klein and Mark Dytham, has become a widely used and easy format for the presentation of new concepts...... their proposals at the final examination of their project work. The authors conclude that Pecha Kucha is suitable for this type of presentations, although the flow of such presentations should be considered if used in connection with formal examination....

  1. The gas turbine: Present technology and future developments; La turbina a gas: Tecnologie attuali e gli sviluppi futuri

    Energy Technology Data Exchange (ETDEWEB)

    Minghetti, E. [ENEA, Centro Ricerche Casaccia, Rome (Italy)

    1997-03-01

    The gas turbine is the most widely used prime mover all over the world for either power generation or mechanical drive applications. The above fact is due to the recent great improvements that have been done especially in terms of efficiency, availability and reliability. The future for gas turbine technological development looks very promising. In fact, although tremendous growth has already taken place, there is still the potential for dramatic improvements in performance. Compared with the competitive prime movers (conventional steam power plants and reciprocating piston engines) the gas turbine technology is younger and still following a strong growth curve. The coming decades will witness the continued increasing in turbine inlet temperature, the development of new materials and refrigeration systems and the commercialization of inter cooled system and steam cooled turbines. With the very soon introduction of the {sup G }and {sup H }technology, expected single and combined cycle efficiencies for heavy duty machines are respectively 40% and 60%, while maintaining single digit levels in pollutant emissions. In this report are given wide information on gas turbine present technology (Thermodynamics, features, design, performances, emission control, applications) and are discussed the main lines for the future developments. Finally are presented the research and technological development activities on gas turbine of Italian National Agency for new Technology Energy and the Environment Energy Department.

  2. Enhanced Cognitive Walkthrough: Development of the Cognitive Walkthrough Method to Better Predict, Identify, and Present Usability Problems

    Directory of Open Access Journals (Sweden)

    Lars-Ola Bligård

    2013-01-01

    Full Text Available To avoid use errors when handling medical equipment, it is important to develop products with a high degree of usability. This can be achieved by performing usability evaluations in the product development process to detect and mitigate potential usability problems. A commonly used method is cognitive walkthrough (CW, but this method shows three weaknesses: poor high-level perspective, insufficient categorisation of detected usability problems, and difficulties in overviewing the analytical results. This paper presents a further development of CW with the aim of overcoming its weaknesses. The new method is called enhanced cognitive walkthrough (ECW. ECW is a proactive analytical method for analysis of potential usability problems. The ECW method has been employed to evaluate user interface designs of medical equipment such as home-care ventilators, infusion pumps, dialysis machines, and insulin pumps. The method has proved capable of identifying several potential use problems in designs.

  3. Developing clinical practice guidelines: types of evidence and outcomes; values and economics, synthesis, grading, and presentation and deriving recommendations.

    Science.gov (United States)

    Woolf, Steven; Schünemann, Holger J; Eccles, Martin P; Grimshaw, Jeremy M; Shekelle, Paul

    2012-07-04

    Clinical practice guidelines are one of the foundations of efforts to improve healthcare. In 1999, we authored a paper about methods to develop guidelines. Since it was published, the methods of guideline development have progressed both in terms of methods and necessary procedures and the context for guideline development has changed with the emergence of guideline clearinghouses and large scale guideline production organisations (such as the UK National Institute for Health and Clinical Excellence). It therefore seems timely to, in a series of three articles, update and extend our earlier paper. In this second paper, we discuss issues of identifying and synthesizing evidence: deciding what type of evidence and outcomes to include in guidelines; integrating values into a guideline; incorporating economic considerations; synthesis, grading, and presentation of evidence; and moving from evidence to recommendations.

  4. The Expected Net Present Value of Developing Weight Management Drugs in the Context of Drug Safety Litigation.

    Science.gov (United States)

    Chawla, Anita; Carls, Ginger; Deng, Edmund; Tuttle, Edward

    2015-07-01

    Following withdrawals, failures, and significant litigation settlements, drug product launches in the anti-obesity category slowed despite a large and growing unmet need. Litigation concerns, a more risk-averse regulatory policy, and the difficulty of developing a product with a compelling risk-benefit profile in this category may have limited innovators' expected return on investment and restricted investment in this therapeutic area. The objective of the study was to estimate perceived manufacturer risk associated with product safety litigation and increased development costs vs. revenue expectations on anticipated return on investment and to determine which scenarios might change a manufacturer's investment decision. Expected net present value of a weight-management drug entering pre-clinical trials was calculated for a range of scenarios representing evolving expectations of development costs, revenue, and litigation risk over the past 25 years. These three factors were based on published estimates, historical data, and analogs from other therapeutic areas. The main driver in expected net present value calculations is expected revenue, particularly if one assumes that litigation risk and demand are positively correlated. Changes in development costs associated with increased regulatory concern with potential safety issues for the past 25 years likely did not impact investment decisions. Regulatory policy and litigation risk both played a role in anti-obesity drug development; however, product revenue-reflecting efficacy at acceptable levels of safety-was by far the most important factor. To date, relatively modest sales associated with recent product introductions suggest that developing a product that is sufficiently efficacious with an acceptable level of safety continues to be the primary challenge in this market.

  5. Combining rhetoric and role-play to introduce and develop patient presentation skills in third year pharmacy students.

    Science.gov (United States)

    Bond, Rucha; Donohoe, Krista L; Jakeman, Berrnadette; Davis, Herbert T; Morgan, Laura

    2017-11-01

    To implement a mock rounds activity designed to introduce and develop patient presentation skills in pharmacy students. The sample population included third-year pharmacy students enrolled at the University of New Mexico (UNM) and Virginia Commonwealth University (VCU) during Fall 2011, 2012, and 2013. A mock rounds activity was developed and implemented in the Pharmaceutical Care Lab setting. Students were assigned an infectious disease case and asked to create an assessment and plan to present orally to an acting preceptor in a small group laboratory setting. Summative assessment of student performance was evaluated using a standardized rubric. A total of 621 students (VCU: 371; UNM: 250) from both universities participated in the mock rounds activity. Data was collected using the rubric. Students scored highest in the areas of respectfulness (94.8% exceeds expectations) and completion time (86.9% exceeds expectations). The lowest ratings were in the areas of logical flow and organization (73.7% exceeds expectations) and ability to answer preceptors' questions (73.3% exceeds expectations). A simulated mock rounds activity enabled students to practice patient case presentation skills and receive summative feedback prior to Advanced Pharmacy Practice Experiences. Copyright © 2017 Elsevier Inc. All rights reserved.

  6. INTEGRATED ON-BOARD COMPUTING SYSTEMS: PRESENT SITUATION REVIEW AND DEVELOPMENT PROSPECTS ANALYSIS IN THE AVIATION INSTRUMENT-MAKING INDUSTRY

    Directory of Open Access Journals (Sweden)

    P. P. Paramonov

    2013-03-01

    Full Text Available The article deals with present situation review and analysis of development prospects for integrated on-board computing systems, used in the aviation instrument-making industry. The main attention is paid to the projects carried out in the framework of an integrated modular avionics. Hierarchical levels of module design, crates (onboard systems and aviation complexes are considered in detail. Examples of the existing products of our country and from abroad and their brief technical characteristics are given and voluminous bibliography on the subject matter as well.

  7. Adaptation and development of software simulation methodologies for cardiovascular engineering: present and future challenges from an end-user perspective.

    Science.gov (United States)

    Díaz-Zuccarini, V; Narracott, A J; Burriesci, G; Zervides, C; Rafiroiu, D; Jones, D; Hose, D R; Lawford, P V

    2009-07-13

    This paper describes the use of diverse software tools in cardiovascular applications. These tools were primarily developed in the field of engineering and the applications presented push the boundaries of the software to address events related to venous and arterial valve closure, exploration of dynamic boundary conditions or the inclusion of multi-scale boundary conditions from protein to organ levels. The future of cardiovascular research and the challenges that modellers and clinicians face from validation to clinical uptake are discussed from an end-user perspective.

  8. MHC class I molecules are present both pre- and postsynaptically in the visual cortex during postnatal development and in adulthood.

    Science.gov (United States)

    Needleman, Leigh A; Liu, Xiao-Bo; El-Sabeawy, Faten; Jones, Edward G; McAllister, A Kimberley

    2010-09-28

    Immune molecules have been discovered recently to play critical roles in the development, function, and plasticity of the cerebral cortex. MHC class I (MHCI) molecules are expressed in the central nervous system and regulate activity-dependent refinement of visual projections during late postnatal development. They have also been implicated in neurodevelopmental diseases such as schizophrenia and autism. Despite the excitement generated by these unique roles for immune proteins in the brain, little is known about how these molecules regulate cortical connections. The first step toward elucidating the mechanism is to identify the spatial and temporal distribution of MHCI proteins throughout development. Using a pan-specific antibody that recognizes many MHCI variants for biochemistry and immunohistochemistry, we found that MHCI proteins are expressed in the rat visual cortex at all ages examined-during the peak of synaptogenesis, the critical period of synaptic refinement, and adulthood. Their abundance in the cortex peaked during early postnatal development, declining during periods of plasticity and adulthood. In contrast to current assumptions, pre- and postembedding immunogold electron microscopy (EM) revealed that MHCI proteins were present both pre- and postsynaptically at all ages examined. They were often found in the postsynaptic density and were closely associated with synaptic vesicles in the presynaptic terminal. These results suggest a previously undescribed model in which MHCI molecules function on both sides of the synapse to regulate connectivity in the mammalian visual cortex before, during, and after the establishment of connections.

  9. Presentation for the first research co-ordination meeting on development of kits for radioimmunometric assays for tumour markers

    International Nuclear Information System (INIS)

    Gavilondo, J.

    1997-01-01

    Regarding to PSA CIGB- IAEA project the center will be generating a panel of monoclonal antibodies against prostatic specific antigen (PSA) free and complexed to α1 antichymotrysin, and tissue polypeptide specific (TPS) antigen as potentially useful markers for the diagnosis of prostate and breast cancer using IRMA or RIA. The panel of monoclonal antibodies would be distributed in Cuba and another countries for the development of diagnostic Kits. The detailed objectives of the contract are: 1. To obtain a panel of monoclonal antibodies against prostatic specific antigen (PSA) complexed antichymotrysin. 2. To obtain a panel of monoclonal antibodies against free PSA. 3. To study the potential use for detect free or complexed PSA in the serum of patients with benign prostatic hypertrophy or prostatic neoplasia. 4. To obtain a panel of monoclonal antibodies against TPS. 5. To develop and validate IRMA or RIA assays using the panel of monoclonal antibodies. The objectives are designed according to the present knowledge on the field of monoclonal antibodies and diagnostic kits. Basic techniques for developing monoclonal antibodies (Mabs) have been used in our division for more than 10 years. The possibility to acquire commercial PSA antigen could reduced the overall time to obtain the Mabs, according with our experience. All these aspects support the idea that the proposing Cuban institutes are able to develop this research project and that its benefits will be applicable in the country and in the region

  10. Present situation of the development of petroleum substitution energy (The UK); Sekiyu daitai energy kaihatsu no genjo (Eikoku)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-03-01

    With relation to the petroleum substitution energy in the U.K., the paper states measures taken for the development and introduction and the state of spread. Introduced were the U.K., energy policy described by energy field, petroleum and natural gas, coal, nuclear power, electric power, renewable energy (petroleum substitution energy), and the policy on energy conservation and the recent trend. Further, the paper took up the environmental policy relating to global warming which is an environmental problem in close connection with the energy industry and described the present status of exhaust gas such as acid rain gas and ozonospherial destruction gas, target for reduction of exhaust gas, and the present situation of exhaust gas at power plant. Explained were the positioning of and the measures for the petroleum substitution energy which was incorporated into a part of the energy policy in the U.K., especially the recent trend of obligation to use non-fossil fuel. First, the order of priority of the governmental policies was introduced, and then the NFFO order was described which was to give reliable fund base to the development toward the practical use of petroleum substitution energy. The paper also commented on recent topics on the state of the practical use of petroleum substitution energy. 2 figs., 7 tabs.

  11. Priorities in the State Policy of Unshadowing the National Economy of Ukraine at the Present Stage of Development

    Directory of Open Access Journals (Sweden)

    Avhustyn Ruslan R.

    2016-11-01

    Full Text Available The aim of the article is to justify the priorities of the state policy of unshadowing the national economy in the system of basic characteristics of the state economic security at the present stage of development. There made a conclusion about the perspectiveness of aligning the policy of economy unshadowing with forming a viable system of economic security of Ukraine, which allows to achieve a synergistic effect oriented both towards counteraction to the shadowing of economic relations and comprehensive enhancement of key parameters of the state economic security, including through the economy unshadowing. Consequently, the strategic priorities are defined in the following areas: (1 self-sufficiency of economic development and provision of the policy of economy unshadowing (forming the environment of perception of the shadow economy, resource support and an information and analytical system of economy unshadowing; introducing effective foreign technologies; increasing the efficiency in the regulatory sphere; (2 stability of the economic system and high capacity of the policy of economy unshadowing (legalization of the national economy in the branch-sectoral as well as spatial and structural aspects by structural elements of the state security, in the financial system and the internal market; (3 ability of the economy to develop and realize the potential of the policy of economy unshadowing (building the infrastructure; introducing «fuses» of control, human and intellectual, investment and innovation support of the economy unshadowing

  12. The development of all-polymer-based piezoelectrically active photocurable resin for 3D printing process (Conference Presentation)

    Science.gov (United States)

    Baker, Evan; Chu, Weishen; Ware, Henry Oliver T.; Farsheed, Adam C.; Sun, Cheng

    2017-02-01

    We present in this work the development and experimental validation of a new piezoelectric material (V-Ink) designed for compatibility with projection stereolithography additive manufacturing techniques. Piezoelectric materials generate a voltage output when a stress is applied to the material, and also can be actuated by using an external voltage and power source. This new material opens up new opportunities for functional devices to be developed and rapidly produced at low cost using emerging 3D printing techniques. The new piezoelectric material was able to generate 115mV under 1N of strain after being polled at 80°C for 40 minutes and the optimal results had a piezoelectric coefficient of 105x10^(-3)V.m/N. The current iteration of the material is a suspension, although further work is ongoing to make the resin a true solution. The nature of the suspension was characterized by a time-lapse monitoring and through viscosity testing. The potential exists to further increase the piezoelectric properties of this material by integrating a mechanical to electrical enhancer such as carbon nanotubes or barium titanate into the material. Such materials need to be functionalized to be integrated within the material, which is currently being explored. Printing with this material on a "continuous SLA" printer that we have developed will reduce build times by an order of magnitude to allow for mass manufacturing. Pairing those two advancements will enable faster printing and enhanced piezoelectric properties.

  13. Biosynthesis of Oxytetracycline by Streptomyces rimosus: Past, Present and Future Directions in the Development of Tetracycline Antibiotics

    Directory of Open Access Journals (Sweden)

    Hrvoje Petković

    2017-01-01

    Full Text Available Natural tetracycline (TC antibiotics were the first major class of therapeutics to earn the distinction of ‘broad-spectrum antibiotics’ and they have been used since the 1940s against a wide range of both Gram-positive and Gram-negative pathogens, mycoplasmas, intracellular chlamydiae, rickett siae and protozoan parasites. The second generation of semisynthetic tetracyclines, such as minocycline and doxycycline, with improved antimicrobial potency, were introduced during the 1960s. Despite emerging resistance to TCs erupting during the 1980s, it was not until 2006, more than four decades later, that a third-generation TC, named tigecycline, was launched. In addition, two TC analogues, omadacycline and eravacycline, developed via (semisynthetic and fully synthetic routes, respectively, are at present under clinical evaluation. Interestingly, despite very productive early work on the isolation of a Streptomyces aureofaciens mutant strain that produced 6-demethyl-7-chlortetracycline, the key intermediate in the production of second- and third-generation TCs, biosynthetic approaches in TC development have not been productive for more than 50 years. Relatively slow and tedious molecular biology approaches for the genetic manipulation of TC-producing actinobacteria, as well as an insufficient understanding of the enzymatic mechanisms involved in TC biosynthesis have significantly contributed to the low success of such biosynthetic engineering efforts. However, new opportunities in TC drug development have arisen thanks to a signifi cant progress in the development of affordable and versatile biosynthetic engineering and synthetic biology approaches, and, importantly, to a much deeper understanding of TC biosynthesis, mostly gained over the last two decades.

  14. Geothermal Development and the Use of Categorical Exclusions Under the National Environmental Policy Act of 1969 (Presentation)

    Energy Technology Data Exchange (ETDEWEB)

    Levine, A.; Young, K. R.

    2014-09-01

    The federal environmental review process under the National Environmental Policy Act of 1969 (NEPA) can be complex and time consuming. Currently, a geothermal developer may have to complete the NEPA process multiple times during the development of a geothermal project. One mechanism to reduce the timeframe of the federal environmental review process for activities that do not have a significant environmental impact is the use of Categorical Exclusions (CXs), which can exempt projects from having to complete an Environmental Assessment or Environmental Impact Statement. This study focuses primarily on the CX process and its applicability to geothermal exploration. In this paper, we: Provide generalized background information on CXs, including previous NEPA reports addressing CXs, the process for developing CXs, and the role of extraordinary circumstances; Examine the history of the Bureau of Land Management's (BLM) geothermal CXs; Compare current CXs for oil, gas, and geothermal energy; Describe bills proposing new statutory CXs; Examine the possibility of standardizing geothermal CXs across federal agencies; and Present analysis from the Geothermal NEPA Database and other sources on the potential for new geothermal exploration CXs. As part of this study, we reviewed Environmental Assessments (EAs) conducted in response to 20 geothermal exploration drilling permit applications (Geothermal Drilling Permits or Notices of Intents) since the year 2001, the majority of which are from the last 5 years. All 20 EAs reviewed for this study resulted in a Finding of No Significant Impact (FONSI). While many of these FONS's involved proponent proposed or federal agency required mitigation, this still suggests it may be appropriate to create or expand an exploration drilling CX for geothermal, which would have a significant impact on reducing geothermal exploration timelines and up-front costs. Ultimately, federal agencies tasked with permitting and completing

  15. Effective factors on the development of medical tourism industry in the West Azerbaijan Province, Iran: Pattern presentation

    Directory of Open Access Journals (Sweden)

    Yousef Mahmoudifar

    2016-07-01

    Full Text Available Nowadays, the market of medical tourism is considered as a revenue and competitive industry throughout the world, it is also regarded as a novel field of the sophisticated tourism. Therefore, most of the developing countries have focused on the medical tourism industry and they are planning for it. In 2016, the present research was conducted with the main objective of devising a pattern for medical tourism development in the West Azerbaijan Province. The statistical population consisted of all medical tourists who referred to the hospitals located in the province. With regard to the krejcie-morgan table and statistical population, the number of the sample was estimated to be equal to 260 persons. These persons were selected based on the multi-stage sampling method. The scholar made questionnaire and studies of the Ricafort and Kazemi were employed as the instrument of collecting data. The validity of questionnaire was confirmed by the experts, professors, supervising and advising professors after applying the required amendments. The reliability was realized using factor analysis method. The PLS method was utilized for analysis of the data. The findings indicate that %82.5 of the variations linked to the medical tourism development has been realized via changes in the two predictor variables (independent variable, including hospital selection and West Azerbaijan selection. Moreover, the two main factors, including hospital selection and West Azerbaijan selection with impact factors of 0.486 and 0.469, respectively have a direct and significant impact on the development of medical tourism of the province. West Azerbaijan Province has so many potentials, and due to this fact there exist very special conditions which can contribute to the development of the medical tourism industry in this region. It can be deduced that by carrying out measures, like creating a brand for province in the medical tourism field, coordination of the corresponding

  16. High risk human papilloma viruses (HPVs) are present in benign prostate tissues before development of HPV associated prostate cancer.

    Science.gov (United States)

    Glenn, Wendy K; Ngan, Christopher C; Amos, Timothy G; Edwards, Richard J; Swift, Joshua; Lutze-Mann, Louise; Shang, Fei; Whitaker, Noel J; Lawson, James S

    2017-01-01

    Although high risk HPVs are associated with an increased risk of prostate cancer it is not known if they have a causal role. The purpose of this study is to investigate the potential role of human papilloma viruses (HPVs) in prostate cancer. The aims are (i) to investigate the presence and confirm the identity of high risk HPVs in benign prostate tissues prior to the development of HPV positive prostate cancer in the same patients, and (ii) to determine if HPVs are biologically active. We used polymerase chain reaction (PCR) to identify HPVs in specimens from 52 Australian men with benign prostate biopsies who 1 to 10 years later developed prostate cancer. Immunohistochemistry (IHC) was used to assess the expression of HPV E7 oncoproteins, cytokeratin and prostate specific antigen (PSA). We used RNASeq data from The Cancer Genome Atlas (TCGA) to identify possible HPV RNA sequences in prostate cancer. HPV screening using standard PCR was conducted on 28 of the 52 sets of benign and later prostate cancers. HPV L1 genes were identified in 13 (46%) benign and 8 (29%) of 28 later prostate cancers in the same patients. HPV E7 genes were identified in 23 (82%) benign and 19 (68%) of 28 subsequent prostate cancers in the same patients. The same HPV types were present in both the benign and subsequent prostate cancers in 9 sets of specimens. HPV type 16 was identified in 15% of benign and 3% of prostate cancers. HPV type 18 was identified in 26% of benign and 16% of prostate cancers. Small numbers of HPV types 45, 47, 76 and 115 were also identified. High confidence RNA-Seq evidence for high risk HPV types 16 and 18 was identified in 12 (2%) of the 502 TCGA prostate cancer transcriptomes. High risk HPV E7 oncoprotein was positively expressed in 23 (82%) of 28 benign prostate specimens but only in 8 (29%) of 28 of the later prostate cancer specimens. This difference is statistically significant ( p  = 0.001). Prostate specific antigen (PSA) was more highly expressed in 26

  17. A Patient on Long-Term Proton Pump Inhibitors Develops Sudden Seizures and Encephalopathy: An Unusual Presentation of Hypomagnesaemia

    Directory of Open Access Journals (Sweden)

    Nirav Y. Gandhi

    2012-01-01

    Full Text Available Objective. To present an unusual but known cause of hypomagnesaemia induced-hypocalcaemia in a chronic GORD patient with severe symptoms with a review of the current literature. Methods. Analysis of the clinical and laboratory findings of the patient and discussion of the multi-factorial nature of his disease and the underlying mechanisms. Results. Our patient described features of magnesium deficiency such as weakness, muscle twitches, and fits with clinical signs of hypocalcaemia: a carpal pedal spasm and paraesthesia. Preadmission blood results revealed low calcium and magnesium levels. He was admitted to ITU, when he presented with seizures and developed encephalopathy. The total vitamin D level was 52.4 nmol/L (>49.9. His U&Es and LFTs were within the normal range with the exception of potassium. He was on Omeprazole for his GORD. With omission of the PPI 1 day after admission and replacement therapy, his ion levels normalised. Conclusion. Hypomagnesaemia is often undiagnosed and is associated with multiple biochemical abnormalities. Treatment focus should be aimed at stopping the PPI and replacing the magnesium. Over use of PPIs is a problem in practice, with the FDA issuing a warning over long-term use. Continued monitoring and decision making on dose reduction/withdrawal is essential to avoid complications.

  18. THE PRESENT CONDITION OF SMALL WATER RETENTION AND THE PROSPECTS OF ITS DEVELOPMENT USING THE EXAMPLE OF THE PODLASKIE VOIVODESHIP

    Directory of Open Access Journals (Sweden)

    Joanna Szczykowska

    2014-07-01

    Full Text Available The necessity and purposefulness of the investments related to water retention are justified mostly due to the preservation of the environment equilibrium as well as due to its farming, anti-flood, landscape and recreation aspects. Reasonable water management where various forms of retention are used gives large chances for the mitigation of the effects of unfavorable phenomena related to its insufficient amount. The creation of plans regarding the formation of reservoirs accumulating water is not necessarily synonymous with their realization. The reason of problems connected with the implementation of plans regarding the formation of new reservoirs lies mainly in financial measures and in problems with obtaining them. Water deficit in Poland is the reason for which the principles of its national usage need to be complied with. Realization of plans at both Voivodeship and municipality level that are focused on small retention will contribute to considerable increase in the retention capacity and will enable considerable increase in available resources in hydrographic catchments of both the characterized area and the entire country. The paper presents the characteristics of the present state and assumes the perspective development of small water retention in the Podlaskie Voivodeship using the example of the Podlaskie Voivodeship.

  19. The integrated reporting: A presentation of the current state of art and aspects of integrated reporting that need further development

    Directory of Open Access Journals (Sweden)

    Jordi Morros

    2016-02-01

    Full Text Available Purpose: The purpose of this paper is to synthesise what is the emerging field of integrated reporting, with particular emphasis in the International Integrated Reporting Council, and outline a list of items for future research in this area. Design/methodology/approach: The approach is to outline a presentation of integrated reporting (IR, and make a review of the implications for the research agenda of the most important items. Findings: The need for quality researchers to address a number of pressing challenges posed by the rapid development of IR policies and practices. Research limitations/implications: The paper provide insights into issues and aspects of integrated reporting that need further development and need robust evidence to help inform improvements in policy and practice. Practical implications: Highlight how companies may benefit from integrated reporting in response to stakeholders’ calls for enhanced disclosure of environmental, social, governance and other non financial information. Social implications: The main social implication is to promote the wider public interest of improving the relevance of information for decision-making, for all stakeholders, and allow greater efficiency in the allocation of financial and other resources and in adding public value Originality/value: This paper offers a general view on a subject that is a challenge for entities oriented to the implementation of sustainability in their values and also in their reporting.

  20. A Survey of Established Veterinary Clinical Skills Laboratories from Europe and North America: Present Practices and Recent Developments.

    Science.gov (United States)

    Dilly, Marc; Read, Emma K; Baillie, Sarah

    Developing competence in clinical skills is important if graduates are to provide entry-level care, but it is dependent on having had sufficient hands-on practice. Clinical skills laboratories provide opportunities for students to learn on simulators and models in a safe environment and to supplement training with animals. Interest in facilities for developing veterinary clinical skills has increased in recent years as many veterinary colleges face challenges in training their students with traditional methods alone. For the present study, we designed a survey to gather information from established veterinary clinical skills laboratories with the aim of assisting others considering opening or expanding their own facility. Data were collated from 16 veterinary colleges in North America and Europe about the uses of their laboratory, the building and associated facilities, and the staffing, budgets, equipment, and supporting learning resources. The findings indicated that having a dedicated veterinary clinical skills laboratory is a relatively new initiative and that colleges have adopted a range of approaches to implementing and running the laboratory, teaching, and assessments. Major strengths were the motivation and positive characteristics of the staff involved, providing open access and supporting self-directed learning. However, respondents widely recognized the increasing demands placed on the facility to provide more space, equipment, and staff. There is no doubt that veterinary clinical skills laboratories are on the increase and provide opportunities to enhance student learning, complement traditional training, and benefit animal welfare.

  1. APECS: A Model Organization for Bridging Past to Present and Developing a New Generation of Polar Scientists (Invited)

    Science.gov (United States)

    Timm, K.; Baeseman, J. L.; Membership, Association Of Polar Early Career Scientists

    2010-12-01

    One of the greatest legacies of the International Polar Year (IPY) is the creation of APECS, the Association of Polar Early Career Scientists. As a grassroots effort, APECS was proposed, formed, and developed by and for early career polar researchers. While the young investigators who founded APECS had talent, ambition, and the desire to make things happen, partnerships with key organizations and experienced leaders in polar science were essential to provide the funding, leadership, and mentorship that has taken the organization well beyond the IPY and to over 2000 members. In four years, APECS has strived to foster the skills of and develop a group of early career interdisciplinary polar scientists through networking and mentoring among themselves and with senior scientists. Through diverse activities including, panel discussions, career development workshops, online seminars, a comprehensive job listing, formal mentoring, meeting travel support, and the APECS Virtual Poster Session, APECS goal is to support the early career researcher being trained to do the science, to become a well-rounded scientist prepared for 21st century careers in science. As part of that training, APECS members are encouraged to participate in activities and training related to science communication, education, and outreach; working with the media; participating in the science / public policy interface; and working with arctic communities and indigenous peoples. During the IPY, APECS members were guest speakers and presenters on International Polar Day activities; they contributed to resources for education and outreach such as the book: Polar Science and Global Climate: An International Resource for Education and Outreach; and they made connections with educators, community groups, the media through in-person presentations, blogs from the field, videos, and much more. Workshops, panels, and online discussions focusing on these activities helped develop the capacity to conduct such

  2. Four CISH paralogues are present in rainbow trout Oncorhynchus mykiss: differential expression and modulation during immune responses and development.

    Science.gov (United States)

    Maehr, Tanja; Vecino, Jose L González; Wadsworth, Simon; Wang, Tiehui; Secombes, Christopher J

    2014-11-01

    Suppressor of cytokine signalling (SOCS) family members are crucial in the control and attenuation of cytokine induced responses via activation of the JAK/STAT, TLR and NF-kB signalling pathways. SOCS proteins orchestrate the termination of many types of immune responses and are often the targets of microbial pathogens exploiting SOCS mechanisms to evade the host's immune response. Through whole and lineage specific genome duplication events, the teleost cytokine/SOCS network is complex. Not only are the orthologues of all mammalian SOCS members present, namely cytokine inducible Src homology 2 (SH2)-containing protein (CISH) and SOCS-1 to -7, but multiple gene copies exist that may potentially become functionally divergent. In this paper we focus on the CISH genes in rainbow trout (Oncorhynchus mykiss), and have cloned two further paralogues, CISHa2 and CISHb2, additional to the known CISHa1 and CISHb1 genes. We present for the first time a comparative expression analysis of these four paralogues, to establish whether subfunctionalisation is apparent. In vivo examination of gene expression revealed a higher constitutive expression level of CISHa paralogues compared to CISHb expression in adult trout tissues. All CISHs were relatively highly abundant in immune tissues but CISHa2 and CISHb2 had highest expression in the heart and muscle. An inverse picture of CISH abundance during trout ontogeny was seen, and further hints at differential roles of the four genes in immune regulation and development. Stimulation of head kidney (HK) leukocytes with trout recombinant interleukin (rIL)-15 and rIL-21 had a major effect on CISHa2 and to a lesser extent CISHa1 expression. In HK macrophages rIL-1β, phytohemagglutinin, and phorbol 12-myristate 13-acetate also had a strong impact on CISHa2 expression. Yersinia ruckeri infection caused a temporally and spatially differential onset of CISH expression that may be viewed in the context of pathogen evasion strategies. These data

  3. PCEE of ATPAE certification program, present and future development; Programa de certificacion PCEE de ATPAE, desarrollo actual y futuro

    Energy Technology Data Exchange (ETDEWEB)

    Plauchu Lima, Alberto [Plachu Consultores, Morelia, Michoacan (Mexico)

    2003-07-01

    In response to the challenges raised to the different actors of the power sector and the users of the electric energy for its optimal application, the Association of Technicians and Professionals in Energy Application (ATPAE) incorporated in its commitments the identification of necessities of specialized professional services, the real availability of these and the necessary actions so that the knowledge, experience and formality are congruent with the required level, quality and trustworthiness for the good performance of those programs, by means of the creation, promotion and development of the Certification Program PCEE (Certificated Personal in Energy Efficiency), as a recognition before the society of the technological dominion, experience and performance of professionals specialized in the power application, qualified and evaluated by the same ATPAE. An anthology of the program is presented and a summary of accomplishments and expectations of future development. [Spanish] En respuesta a los retos planteados a los diferentes actores del sector energetico y de los usuarios de la energia para la aplicacion optima de esta, la Asociacion de Tecnicos y Profesionales en Aplicacion Energetica (ATPAE) incorporo en sus compromisos la identificacion de necesidades de servicios profesionales especializados, la disponibilidad real de estos y las acciones necesarias para que el conocimiento, experiencia y formalidad sean congruentes con el nivel, calidad y confiabilidad requeridos para el buen desempeno de esos programas, mediante la creacion, promocion y desarrollo del Programa de Certificacion PCEE (Personal Certificado en Eficiencia Energetica), como un reconocimiento ante la sociedad del dominio tecnologico, experiencia y desempeno de profesionales especializados en el campo de aplicacion energetica, calificados y evaluados por la propia ATPAE. Se presenta una antologia del programa y un resumen de realizaciones y expectativas de desarrollo futuro.

  4. Selection of quality assurance programme levels for nuclear power plants. Present practice in Canada and future developments

    International Nuclear Information System (INIS)

    Thomas, R.A.

    1982-01-01

    According to the IAEA Code of Practice on the subject and also to numerous national standards, effective quality assurance (QA) for safety in nuclear power plants depends upon the application of a number of fundamental principles. One of these principles is that QA for systems, components and structures should be commensurate with the individual importance to safety of each item. Evidently, money spent on excessive QA may be partly or wholly wasted, while too little QA will provide insufficient confidence that an item will perform satisfactorily in service. To deal successfully with the requirement of 'importance to safety', a detailed methodology must be established, by means of which QA can be prescribed rationally and consistently. Set in the context of the Canadian nuclear power and nuclear standards programmes, two related methodologies which account for importance to safety as well as for some other specific factors have been developed and are in use. These related methodologies are applied to the manufacture and installation of safety-related items, and are based on the implementation of the fixed-step, graded standards of the Canadian Standards Association, CSA Z299. Information is presented on the main features of the methodologies and on Canadian nuclear power plant QA practice in general. (author)

  5. Features, present condition of development and future scope on the high temperature gas reactor as an innovative one

    International Nuclear Information System (INIS)

    Shiozawa, Shusaku

    2001-01-01

    The high temperature gas reactor has some features without previous reactors such as high temperature capable of taking-out, high specific safety, feasibility adaptable to versatile fuel cycle, and so on. Then, it is expected to be an innovative reactor to contribute to diversification of energy supply and expansion of energy application field. In Japan, under the HTTR (high temperature engineering test reactor) plan, construction of HTTR, which is the first high temperature gas reactor in Japan, was finished and its output upgrading test has been promoted. And, on the HTTR plan, together with promotion of full power operation, reactor performance tests, safety proof test, and so on, it is planned to carry out study on application of the high temperature heat such as hydrogen production and so on to aim to practise establishment and upgrading of technologies on high temperature gas reactor in Japan. Here were introduced features and present condition of development of the high temperature gas reactor as an innovative type reactor and described role and future scope in Japan. (G.K.)

  6. Presentation Technique

    International Nuclear Information System (INIS)

    Froejmark, M.

    1992-10-01

    The report presents a wide, easily understandable description of presentation technique and man-machine communication. General fundamentals for the man-machine interface are illustrated, and the factors that affect the interface are described. A model is presented for describing the operators work situation, based on three different levels in the operators behaviour. The operator reacts routinely in the face of simple, known problems, and reacts in accordance with predetermined plans in the face of more complex, recognizable problems. Deep fundamental knowledge is necessary for truly complex questions. Today's technical status and future development have been studied. In the future, the operator interface will be based on standard software. Functions such as zooming, integration of video pictures, and sound reproduction will become common. Video walls may be expected to come into use in situations in which several persons simultaneously need access to the same information. A summary of the fundamental rules for the design of good picture ergonomics and design requirements for control rooms are included in the report. In conclusion, the report describes a presentation technique within the Distribution Automation and Demand Side Management area and analyses the know-how requirements within Vattenfall. If different systems are integrated, such as geographical information systems and operation monitoring systems, strict demands are made on the expertise of the users for achieving a user-friendly technique which is matched to the needs of the human being. (3 figs.)

  7. Technical Meeting/Workshop on Topical Issues on Infrastructure Development: Managing the Development of a National Infrastructure for Nuclear Power Plants. Presentations

    International Nuclear Information System (INIS)

    2012-01-01

    The main purpose of the TM/Workshop is to provide an opportunity for exchange of specific information on the management of the development of a sustainable national infrastructure for Nuclear Power Plants as it is recommended in the Agency's Milestones approach. Taking into account the actual status of new nuclear power programmes in Member States, this Agency event shall focus on the moving beyond the consideration of the nuclear power and advancing to the next phase, when future partners (Consultants, NPP Vendors, EPC Contractors, etc.) shall be selected and contracted for the first Nuclear Power Plant. The objectives of the Technical Meeting/Workshop are the following: 1. To exchange specific information and to facilitate the management and coordination of the development and implementation of a national infrastructure for nuclear power; 2. To present and discuss case studies, good practices and lessons learned about recent experiences in implementing an appropriate infrastructure for nuclear power, including management methods and self-evaluation processes; 3. To allow participants to improve their knowledge of various aspects of nuclear infrastructure development; and 4. To provide a forum in which participants can discuss common challenges, opportunities for cooperation, concerns and issues their countries face in the infrastructure implementation process.

  8. Tool Support for Distributed Software Development : The past - present - and future of gaps between user requirements and tool functionalities

    NARCIS (Netherlands)

    Herrera, Miles; van Hillegersberg, Jos; Harmsen, Frank; Amrit, Chintan Amrit; Geisberger, Eva; Keil, Patrick; Kuhrmann, Marco

    2007-01-01

    This paper presents the past, present, and our view on future user requirements and tool functionalities supporting Globally Distributed Software Teams and highlights the changing emphasis in these user requirements.

  9. Synthetic Resins in Aircraft Construction - Their Composition, Properties, Present State of Development and Application to Light Structures

    Science.gov (United States)

    Riechers, K

    1937-01-01

    This report gives a brief review of the properties that have been attained with the synthetic materials with which we are at present familiar. Results of investigations are presented as well as possibilities for construction applications. Endurance strength and bonding tests are also presented.

  10. Baseline characteristic of patients presenting with lacunar stroke and cerebral small vessel disease may predict future development of depression.

    Science.gov (United States)

    Pavlovic, Aleksandra M; Pekmezovic, Tatjana; Zidverc Trajkovic, Jasna; Svabic Medjedovic, Tamara; Veselinovic, Nikola; Radojicic, Aleksandra; Mijajlovic, Milija; Tomic, Gordana; Jovanovic, Zagorka; Norton, Melanie; Sternic, Nada

    2016-01-01

    Cerebral small vessel disease (SVD) is associated with late-onset depression and increases the risk for depression after stroke. We aimed to investigate baseline predictors of depression after long-term follow-up in patients with SVD, initially presenting with first-ever lacunar stroke, free of depression and cognitive impairment. A total of 294 patients with SVD were evaluated 3-5 years after the qualifying event. We analyzed baseline demographic data, vascular risk factors, functional status expressed as a score on modified Rankin Scale (mRS), cognitive status, presence of depression, total number of lacunar infarcts and severity of white matter hyperintensities (WMH) on MRI with Age-Related White Matter Changes scale total score (tARWMC) and Fazekas scale periventricular and deep subcortical scores. On follow-up, depression was registered in 117 (39.8%) SVD patients. At the baseline, patients with depression compared with non-depressed were older (64.4 vs 60.9 years; p = 0.007), had higher mRS score (2.8 ± 0.7 vs 1.5 ± 0.7; p depressed patients more frequently exhibited cognitive decline (75.2% depressed vs 56.5% non-depressed; p = 0.003). No difference was detected in risk factor frequency between groups. Multivariate Cox regression analysis adjusted by age and gender revealed independent predictors of depression: baseline mRS >2 (HR 2.17, 95%CI 1.74-2.72; p cognitive decline on follow-up (HR 1.80, 95%CI 1.12-2.89; p = 0.015). Baseline functional status and severity of WMH and development of cognitive decline predict the occurence of late-onset depression in patients with SVD. Copyright © 2015 John Wiley & Sons, Ltd.

  11. Development of School-Based Asthma Management Programs in Rochester, New York: Presented in Honor of Dr Robert Haggerty.

    Science.gov (United States)

    Halterman, Jill S; Tajon, Reynaldo; Tremblay, Paul; Fagnano, Maria; Butz, Arlene; Perry, Tamara T; McConnochie, Kenneth M

    2017-08-01

    In the spirit of Dr. Haggerty's teachings, we present an overview of our work to improve care for children with asthma in the context of 3 lessons learned: 1) the importance of providing integrated services across disciplinary boundaries for children with chronic illness, 2) the need to move from a care model focused only on the individual child to a model focused on the child, family, and community, and 3) the need to expand beyond the local community and take a broad perspective on improving health on a national level. The goal of our program is to develop sustainable models to overcome the multiple obstacles to effective preventive care for urban children with asthma. The primary intervention for our original School-Based Asthma Therapy program was directly observed administration of preventive asthma medications in school (with dose adjustments on the basis of National Heart, Lung, and Blood Institute guidelines). We found that children who received preventive medications in school through directly observed therapy had improved outcomes across multiple outcome measures. Our subsequent asthma programs have focused on dissemination and sustainability, with the incorporation of communication technology to enhance the system of care. We are currently testing the 'School-Based Telemedicine Enhanced Asthma Management' program, including 400 children with persistent asthma from the Rochester City School District. This program includes directly observed administration of preventive asthma medication at school, and school-based telemedicine to assure appropriate evaluation, preventive medication prescription, and follow-up care. It is designed to implement and sustain guideline-based asthma care through existing community infrastructure, and could serve as a model for the integration of services in rural as well as urban communities. Copyright © 2017 Academic Pediatric Association. Published by Elsevier Inc. All rights reserved.

  12. A novel 1050nm handheld OCT imaging system for pediatric retinoblastoma patients: technology development and clinical study (Conference Presentation)

    Science.gov (United States)

    Nadiarnykh, Oleg; Moll, Annette C.; de Boer, Johannes F.

    2016-03-01

    We demonstrate a novel optical coherence tomography system specifically developed and validated for clinical imaging of retinoblastoma tumors in pediatric patients. The existing treatment options for this malignant tumor of the retina aim at reduction of tumor (re)growth risks, and vision preservation. The choice of optimal treatment strongly depends on skilled and detailed clinical assessment. Due to the limitations of the existing real-time diagnostic tools the patients at risk are periodically monitored with retinal imaging to confirm the absence of new tumor seedings. Three-dimensional visualization of tissue layer and microvasculature at improved axial and lateral resolution of interference-based OCT imaging provides sensitivity for detection of vital tumor tissue concurrent with local treatment. Our METC-approved system accommodates for the range of optical parameters of infants' eyes, and uses the 1050nm wavelength to access the deeper choroid layers of retina. The prototype is designed for patients in supine position under general anesthesia, where ergonomic handheld module is connected to fiber-based optical setup via umbilical cord. The system conforms to clinical safety requirements, including fully isolated low-voltage electric circuit. Focusing is performed with a mechanically tunable lens, where resolution is 6 µm axially, and varies with focusing at 10-18µm laterally. We will present optical design, performance limitations, and results of the ongoing clinical study, including the increased OCT diagnostic sensitivity in three dimensions in comparison with the established clinical imaging modalities. We will discuss images of early, active, and treated tumors, as well as follow-up on patients after local and systemic treatments.

  13. Development of InCVAX as a novel in situ autologous vaccine for metastatic cancers (Conference Presentation)

    Science.gov (United States)

    Hode, Tomas; Alleruzzo, Luciano; Raker, Joseph; Lam, Samuel Siu Kit; Nordquist, Robert E.; Chen, Wei R.

    2016-03-01

    A novel method, an in situ autologous whole-cell cancer vaccine (inCVAX), is being developed by Immunophotonics, Inc., for the treatment of metastatic cancers. inCVAX combines phototherapy and immunotherapy to potentially induce a systemic anti-tumor immune response in the hosts. Immunophotonics and its academic partners have spent years conducting nonclinical research, developing CMC techniques and conducting clinical research. In 2015 the company initiated a late-stage (II/III) clinical trial in South America for advanced breast cancer patients. The process of developing the inCVAX approach from a laboratory setting into clinical trials requires significant efforts from a group of dedicated engineers, scientists, and physicians. The growth of the company and its business advances demonstrated the determination of a group of visionary investors, entrepreneurs, and business leaders. This talk will chronicle the milestones of the scientific achievement, medical progress, and business development of Immunophotonics.

  14. Delivery presentations

    Science.gov (United States)

    Pregnancy - delivery presentation; Labor - delivery presentation; Occiput posterior; Occiput anterior; Brow presentation ... The mother can walk, rock, and try different delivery positions during labor to help encourage the baby ...

  15. Social Development and Happiness in Nations : Presentation at conference "Taking stock: Measuring social development" December 14-15 2011, International Institute of Social Studies, The Hague

    NARCIS (Netherlands)

    R. Veenhoven (Ruut)

    2012-01-01

    textabstractThe term "social development" is used rhetorically in pleas for less focus on "economic development". In that context it is commonly assumed that social development will add to human happiness and more so than economic development does. These claims are checked in an analysis of 141

  16. Research and development program in fiber optic sensors and distributed sensing for high temperature harsh environment energy applications (Conference Presentation)

    Science.gov (United States)

    Romanosky, Robert R.

    2017-05-01

    he National Energy Technology Laboratory (NETL) under the Department of Energy (DOE) Fossil Energy (FE) Program is leading the effort to not only develop near zero emission power generation systems, but to increaser the efficiency and availability of current power systems. The overarching goal of the program is to provide clean affordable power using domestic resources. Highly efficient, low emission power systems can have extreme conditions of high temperatures up to 1600 oC, high pressures up to 600 psi, high particulate loadings, and corrosive atmospheres that require monitoring. Sensing in these harsh environments can provide key information that directly impacts process control and system reliability. The lack of suitable measurement technology serves as a driver for the innovations in harsh environment sensor development. Advancements in sensing using optical fibers are key efforts within NETL's sensor development program as these approaches offer the potential to survive and provide critical information about these processes. An overview of the sensor development supported by the National Energy Technology Laboratory (NETL) will be given, including research in the areas of sensor materials, designs, and measurement types. New approaches to intelligent sensing, sensor placement and process control using networked sensors will be discussed as will novel approaches to fiber device design concurrent with materials development research and development in modified and coated silica and sapphire fiber based sensors. The use of these sensors for both single point and distributed measurements of temperature, pressure, strain, and a select suite of gases will be addressed. Additional areas of research includes novel control architecture and communication frameworks, device integration for distributed sensing, and imaging and other novel approaches to monitoring and controlling advanced processes. The close coupling of the sensor program with process modeling and

  17. Developing interactive land use scenarios on the Loess Plateau in China, presenting risk analyses and economic impacts

    NARCIS (Netherlands)

    Stolte, J.; Ritsema, C.J.; Bouma, J.

    2005-01-01

    This study aimed to present a risk analysis of the effects of different land use scenarios on reducing soil and water losses, using a physically based hydrological and soil erosion model. We quantified the effect of various land use scenarios on the expected rate of discharge and sediment loss

  18. Pattern of presentation and management of Ca breast in developing countries. There is a lot to do

    International Nuclear Information System (INIS)

    Malik, A.M.; Pathan, R.; Shaikh, N.A.; Qureshi, J.N.; Talpur, K.A.H.

    2010-01-01

    To investigate the pattern of presentation, severity, factors responsible for delayed presentation and outcome of breast cancer in patients presenting to a teaching hospital of Jamshoro. Methods: It's a prospective descriptive study of 103 malignant breast lumps treated at a tertiary care teaching hospital over a period of 8 years. All patients were admitted through Outpatients department and were thoroughly examined and investigated. Treatment offered was based on triple assessment and ranged from lumpectomy to toilet mastectomy depending upon the stage of disease. The variables studied were recorded on a proforma and analyzed on SPSS version 12 for measuring frequencies and using Chi square test where applicable. Results: The mean age of the study population was 39.17 +- 6.019 years and a range of 22 to 54 years. The frequency of advanced malignancy was alarmingly high in younger patients. Intra-ductal carcinoma was the commonest tumour in 93 (90%) patients, while the remaining included lobular and Paget's disease. The high figures of advanced disease at presentation is attributed to lack of knowledge and education, poverty and local customs of women not exposing themselves even to the physicians. In addition, there is a substantial delay in the referral of patients from under privileged, remote areas where patients continue to receive symptomatic treatment till such time that disease becomes incurable. Conclusion: Advanced breast disease is common in younger patients belonging to underprivileged and remote rural areas. Great efforts are required to educate people so as to make early diagnosis possible. (author)

  19. Geology and geochemistry of paleosols developed on the Hekpoort Basalt, Pretoria Group, South Africa

    Science.gov (United States)

    Rye, R.; Holland, H. D.

    2000-01-01

    The Hekpoort paleosols comprise a regional paleoweathering horizon developed on 2.224 +/- 0.021 Ga basaltic andesite lavas at the top of the Hekpoort Formation of the Pretoria Group, Transvaal Supergroup, South Africa. In five separate profiles, from outcrops along road cuts near Waterval Onder and the Daspoort Tunnel and in three drill cores from the Bank Break Area (BB3, BB8, and BB14), the top of the paleosol is a sericite-rich zone. The sericite zone grades downward into a chlorite-rich zone. In core BB8 and in the road cut at the Daspoort Tunnel, we sampled the underlying or parent basaltic andesite into which the chlorite zone grades. We did not obtain samples of the parent material at Waterval Onder and in cores BB3 and BB14, but chemical analyses indicate that the chlorite and sericite zones in these profiles derive from underlying lavas similar to the ones we sampled in core BB8 and at the Daspoort Tunnel. The presence of apparent rip-up clasts of the paleosol in the overlying ironstones of the Strubenkop Formation in the cores from Bank Break makes it very unlikely that most of the alteration was a result of interactions with hydrothermal fluids. Desiccation cracks at the top of the paleosol that were filled with sand during the deposition of the overlying sediments at Waterval Onder point to a subaerial weathering origin. Very little, if any, Al, Ti, Zr, V, or Cr moved a discernible distance during weathering of any of the five profiles. The vertical distribution of Fe, Mg, Mn, Ni, and Co indicates that these elements were largely removed from the top of the soil during weathering. The overall abundance of these elements in each of the profiles indicates that a significant fraction of the complement lost from the top subsequently reprecipitated in the lower portion of the soil as constituents of an Fe2(+) -rich smectite. The loss of Fe from the top of the soil during weathering of the Hekpoort paleosols indicates that atmospheric PO2 was less than 8 x 10

  20. Development and application of a robust speciation method for determination of six arsenic compounds present in human urine.

    OpenAIRE

    Milstein, Lisa S; Essader, Amal; Pellizzari, Edo D; Fernando, Reshan A; Raymer, James H; Levine, Keith E; Akinbo, Olujide

    2003-01-01

    Six arsenic species [arsenate, arsenite, arsenocholine, arsenobetaine, monomethyl arsonic acid, and dimethyl arsinic acid] present in human urine were determined using ion-exchange chromatography combined with inductively coupled plasma mass spectrometry (IC-ICP-MS). Baseline separation was achieved for all six species as well as for the internal standard (potassium hexahydroxy antimonate V) in a single chromatographic run of less than 30 min, using an ammonium carbonate buffer gradient (betw...

  1. The integrated reporting: A presentation of the current state of art and aspects of integrated reporting that need further development

    OpenAIRE

    Morrós Ribera, Jordi

    2016-01-01

    Purpose: The purpose of this paper is to synthesise what is the emerging field of integrated reporting, with particular emphasis in the International Integrated Reporting Council, and outline a list of items for future research in this area. Design/methodology/approach: The approach is to outline a presentation of integrated reporting (IR), and make a review of the implications for the research agenda of the most important items. Findings: The need for quality researchers to address a number ...

  2. Development of near infrared I-III-VI quantum dots for in vivo imaging applications (Conference Presentation)

    Science.gov (United States)

    Pons, Thomas

    2017-02-01

    Near infrared (NIR) emitting quantum dots based on copper indium chalcogenides present unique optical properties for in vivo fluorescence imaging. Here we present the synthesis of CuIn(S,Se)2/ZnS core/shell QDs with 30-50% quantum yield in the NIR range. These nanoprobes are solubilized in water using a block copolymer surface ligand composed of multiple binding groups for enhanced stability and zwitterionic groups for solubility and minimized nonspecific adsorption. They present limited toxicity compared to heavy metal-containing QDs. These versatile nanoprobes can be directly injected in the peritumoral region for sentinel lymph node imaging. We also demonstrate their vectorization with RGD peptides or their incorporation in folic acid-functionalized silica particles to target specific cancer cells. Their long fluorescence lifetime enables rejection of autofluorescence using time-gated detection. This considerably enhances the sensitivity of in vivo fluorescence imaging. These QDs have been used for long term labeling of cancer cells ex vivo. Following reinjection of these cells, time-gated detection enables in vivo imaging of these cancer cells in the blood stream at the single cell level. Finally, these QDs can be doped with paramagnetic manganese ions to provide multimodal contrast in both fluorescence and magnetic resonance imaging.

  3. Production of radioisotopes by cyclotron at the Instituto de Engenharia Nuclear - an evaluation of the present stage of development

    International Nuclear Information System (INIS)

    Almeida, G.L. de; Britto, J.L.Q. de; Osso Junior, J.A.; Bastos, M.A.V.; Braghirolli, A.M.S.; Chamma, D.F.S.; Silva, A.G. da

    1984-01-01

    Since 1974 a variable energy isochronous cyclotron (CV-28) is operating at Instituto de Engenharia Nuclear in Rio de Janeiro, with the main purpose of producing radioisotopes for medical diagnosis. To accomplish this, besides the conventional chemical laboratories and related facilities, hot chemistry laboratories with their specific equipment and remote handling devices had to be designed and constructed at this Institute, and are still being developed, due to a lack of engineering companies working in this field. Other equipment, intrinsically related to cyclotrons like high power density target holders, collimators etc. were also conceived and constructed. Among the produced raioisotopes, high purity gallium-67 and indium-111 have been periodically sent to hospitals and some efforts are still being made in order to improve and simplify the chemical processing as well as the operational procedures. Some work has also been devoted to the development and improvement of methods for the production of iodine-123, bromine-77 and thallium-201. (Author) [pt

  4. Innovation and presentation of RALSPI model: a new method for evaluating alternatives and assessment of development level of settlements

    OpenAIRE

    M. Taghvaei; R. Sheykh Beygloo

    2013-01-01

    Extended Abstract1- IntroductionIn this paper, Ranking Alternatives by Limiting Substitution Possibilities of Indicators (RALSPI) method is proposed as a Multiple Criteria Decision Making (MCDM) method. Many MCDM methods have been developed over the years, but little is known about their shortcomings on similar problems. This study explores the main faults of some of the classical MCDM methods including SAW, TOPSIS, AHP, LINMAP, Numerical Taxonomy and Morris. The rationale for such selection ...

  5. Alternatives and actions regarding solid residues, presented by Jimenez and Oreamuno municipalities and their relation to development and sustainability (Informative)

    OpenAIRE

    Campos-Rodríguez, Rooel; Quiros-Bustos, Noemy; Navarro-Garro, Alfonso

    2013-01-01

    Currently, the production processes are not efficient, which contributes to the generation of waste. In Costa Rica the municipalities are responsible for the integrated management of solid waste. That is why this research focuses on issues of waste management which has become a major environmental problem. So, it is necessary to confront these issues from the perspective of sustainable development, requiring a new vision and awareness of people regarding the environment and the problem of sol...

  6. Use of a highly transparent zebrafish mutant for investigations in the development of the vertebrate auditory system (Conference Presentation)

    Science.gov (United States)

    Wisniowiecki, Anna M.; Mattison, Scott P.; Kim, Sangmin; Riley, Bruce; Applegate, Brian E.

    2016-03-01

    Zebrafish, an auditory specialist among fish, offer analogous auditory structures to vertebrates and is a model for hearing and deafness in vertebrates, including humans. Nevertheless, many questions remain on the basic mechanics of the auditory pathway. Phase-sensitive Optical Coherence Tomography has been proven as valuable technique for functional vibrometric measurements in the murine ear. Such measurements are key to building a complete understanding of auditory mechanics. The application of such techniques in the zebrafish is impeded by the high level of pigmentation, which develops superior to the transverse plane and envelops the auditory system superficially. A zebrafish double mutant for nacre and roy (mitfa-/- ;roya-/- [casper]), which exhibits defects for neural-crest derived melanocytes and iridophores, at all stages of development, is pursued to improve image quality and sensitivity for functional imaging. So far our investigations with the casper mutants have enabled the identification of the specialized hearing organs, fluid-filled canal connecting the ears, and sub-structures of the semicircular canals. In our previous work with wild-type zebrafish, we were only able to identify and observe stimulated vibration of the largest structures, specifically the anterior swim bladder and tripus ossicle, even among small, larval specimen, with fully developed inner ears. In conclusion, this genetic mutant will enable the study of the dynamics of the zebrafish ear from the early larval stages all the way into adulthood.

  7. Present situation of the development of petroleum substitution energy (Germany); Sekiyu daitai energy kaihatsu no genjo (Doitsu)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-03-01

    The paper investigates and reports the developmental trend of petroleum substitution energy in Germany. Policies for the technical development and actual introduction of petroleum substitution energy in Germany are concerned with three energies: coal, natural gas, and new energy, except nuclear energy the use of which is against public opinion. Coal is the only abundant domestic resource, but not internationally competitive because of its cost. Brown coal obtained from the open pit mining is an abundant and low-cost domestic resource, but has the environmental problem. The latest technology is actually being introduced in which the thermal power generation is integrated into gasification, and the gas/steam turbine power generation. Natural gas is advancing in the use as energy source for space heating substituting for brown coal. The technology development of new energy is promoted mainly on such wind power and solar energy as are called renewable energy. As to the development of technology using renewable energy for which the rapid increasing use is not expected in near future, the target is directed mostly to CO2 control and the third world where there are no public electric power nets. 30 refs., 10 figs., 8 tabs.

  8. Development of an optimized algorithm for the characterization of microflow using speckle patterns present in optical coherence tomography signal

    International Nuclear Information System (INIS)

    Pretto, Lucas Ramos de

    2015-01-01

    This work discusses the Optical Coherence Tomography system (OCT) and its application to the microfluidics area. To this end, physical characterization of microfluidic circuits were performed using 3D (three-dimensional) models constructed from OCT images of such circuits. The technique was thus evaluated as a potential tool to aid in the inspection of microchannels. Going further, this work paper studies and develops analytical techniques for microfluidic flow, in particular techniques based on speckle pattern. In the first instance, existing methods were studied and improved, such as Speckle Variance - OCT, where a gain of 31% was obtained in processing time. Other methods, such as LASCA (Laser Speckle Contrast Analysis), based on speckle autocorrelation, are adapted to OCT images. Derived from LASCA, the developed analysis technique based on intensity autocorrelation motivated the development of a custom OCT system as well as an optimized acquisition software, with a sampling rate of 8 kHz. The proposed method was, then, able to distinguish different flow rates, and limits of detection were tested, proving its feasibility for implementation on Brownian motion analysis and flow rates below 10 μl/min. (author)

  9. Ion-stimulated gas desorption yields of electropolished, chemically etched, and coated (Au, Ag, Pd, TiZrV stainless steel vacuum chambers and St707 getter strips irradiated with 4.2  MeV/u lead ions

    Directory of Open Access Journals (Sweden)

    E. Mahner

    2005-05-01

    Full Text Available The ion-induced desorption experiment, installed in the CERN Heavy-Ion Accelerator LINAC 3, has been used to measure molecular desorption yields for 4.2  MeV/u lead ions impacting under grazing incidence on different accelerator-type vacuum chambers. Desorption yields for H_{2}, CH_{4}, CO, and CO_{2}, which are of fundamental interest for future accelerator applications, are reported for different stainless steel surface treatments. In order to study the effect of the surface oxide layer on the gas desorption, gold-, silver-, palladium-, and getter-coated 316 LN stainless steel chambers and similarly prepared samples were tested for desorption at LINAC 3 and analyzed for chemical composition by x-ray photoemission spectroscopy. The large effective desorption yield of 2×10^{4}   molecules /Pb^{53+} ion, previously measured for uncoated, vacuum fired stainless steel, was reduced after noble-metal coating by up to 2 orders of magnitude. In addition, pressure rise measurements, the effectiveness of beam scrubbing with lead ions, and the consequence of a subsequent venting on the desorption yields of a beam-scrubbed vacuum chamber are described. Practical consequences for the vacuum system of the future Low Energy Ion Ring are discussed.

  10. Present status and future developments of the implementation of burnup credit in spent fuel management systems in Germany

    International Nuclear Information System (INIS)

    Neuber, J.C.; Kuehl, H.

    2001-01-01

    This paper describes the experience gained in Germany in implementing burnup credit in wet storage and dry transport systems of spent PWR, BWR, and MOX fuel. It gives a survey of the levels of burnup credit presently used, the regulatory status and activities planned, the fuel depletion codes and criticality calculation codes employed, the verification methods used for validating these codes, the modeling assumptions made to ensure that the burnup credit criticality analysis is based on a fuel irradiation history which leads to bounding neutron multiplication factors, and the implementation of procedures used for fuel loading verification. (author)

  11. [The role of surrogate alcoholic beverages in the development of hemorrhage in the patients presenting with Mallory-Weiss syndrome].

    Science.gov (United States)

    Pavlov, A L; Bogomolov, D V; Savin, A A

    2015-01-01

    The objective of the present work was to study the pathological changes in various organs and tanatogenesis associated with Mallory-Weiss syndrome making use of the forensic medical and clinical materials. It was shown that the main cause of unrestrained vomiting resulting from alcoholic intoxication and leading to perfusive bleeding is not only the direct action of ethanol and surrogate alcohol on gastroesophageal mucosa and induced thrombocytopenia. Another cause may be brain oedema with subsequent cerebral herniation and irritation of the pseudobulbar centres responsible for the initiation of the vomiting reflex. The authors propose recommendations for forensic medical diagnostics of the cases of such hemorrhage.

  12. Delivery presentations

    Science.gov (United States)

    ... is delivered under the pubic bone. After the shoulder, the rest of the body is usually delivered without a problem. Alternative Names Shoulder presentation; Malpresentations; Breech birth; Cephalic presentation; Fetal lie; ...

  13. Thousands of RNA-cached copies of whole chromosomes are present in the ciliateOxytrichaduring development.

    Science.gov (United States)

    Lindblad, Kelsi A; Bracht, John R; Williams, April E; Landweber, Laura F

    2017-08-01

    The ciliate Oxytricha trifallax maintains two genomes: a germline genome that is active only during sexual conjugation and a transcriptionally active, somatic genome that derives from the germline via extensive sequence reduction and rearrangement. Previously, we found that long noncoding (lnc) RNA "templates"-telomere-containing, RNA-cached copies of mature chromosomes-provide the information to program the rearrangement process. Here we used a modified RNA-seq approach to conduct the first genome-wide search for endogenous, telomere-to-telomere RNA transcripts. We find that during development, Oxytricha produces long noncoding RNA copies for over 10,000 of its 16,000 somatic chromosomes, consistent with a model in which Oxytricha transmits an RNA-cached copy of its somatic genome to the sexual progeny. Both the primary sequence and expression profile of a somatic chromosome influence the temporal distribution and abundance of individual template RNAs. This suggests that Oxytricha may undergo multiple rounds of DNA rearrangement during development. These observations implicate a complex set of thousands of long RNA molecules in the wiring and maintenance of a highly elaborate somatic genome architecture. © 2017 Lindblad et al.; Published by Cold Spring Harbor Laboratory Press for the RNA Society.

  14. Presentation for the first research co-ordination meeting on development of kits for radioimmunometric assays for tumour markers

    International Nuclear Information System (INIS)

    Liu Yibing

    1997-01-01

    Radioimmunoassay and Labeled Compound Lab. is the earliest and biggest center which supply RIA reagents in China. It started the research on RIA reagents in the middle of 1970's. Now it can produce more than 80 kinds of RIA kits including thyroid function and newborn screening, tumor markers, kidney function, diabetes-related, fertility and pregnancy monitoring and diagnosis of hepatitis B and C. There are over 1000 hospitals and research organizations using the reagents. Cancer is a disease which endanger human life. There are about 1.6 million new cancer patient and 800 thousand persons died of cancer every year in our country. The laboratory has been paying attention to development of tumor markers RIA reagents since we started the research on RIA reagents. The first kit produced was Rocket Electrophoresis Radioautograph of AFP. In 1980's it developed AFP, CEA, HCG and Ferritin RIA kits. Now RIA reagents for tumor markers have become important part of our products . Besides the products above mentioned it also can produce calcitonin RIA, thyroidglobulin RIA and CA125 IRMA. In early 1990's it established a monoclonal antibody Lab. and this Lab. have been working for the preparation of the monoclonal antibody to tumor markers

  15. Present state of works on development of electron accelerators for energy consuming processes at Efremov Research Institute

    International Nuclear Information System (INIS)

    Ivanov, A.S.; Maznev, V.P.; Ovchinnikov, V.P.; Svinin, M.P.; Tolstun, N.G.

    2011-01-01

    Necessity to decrease anthropogenic environmental pollution puts a task of development of HV accelerators for introduction of nature conservation technologies in commercial scale. High efficiency and operation reliability in a power range noticeably higher than already mastered level are required. In design of the accelerators basic units, namely, HV generators, accelerating structures, electron beam irradiation field forming systems and extraction devices solutions that demonstrated already theirs operational capacity in the machines of a lesser power may be used. From the other hand, experience gained by already full-scale built powerful installations shows that a number of problems remain unsolved that put obstacles on a way of wide implementation of exhaust gases irradiation processing. Attempts to built the accelerator meeting all requirements in a frame of specific contracts, although already shown noticeable progress in a sense of the power grow, acquiring of very valuable experience, carry some risk caused by insufficient study of the problems connected with power increasing, lack of time and means for the thorough research works. It looks reasonable to suggest creation of full-scale pilot installation with HV accelerator of required power (1 MW, for example) not bound to a specific commercial contract, where researches and studies of the accelerator main systems, theirs optimization and longevity tests can be carried out thus providing development of the accelerator into really reliable and effective tool for applying to environmental tasks

  16. Design constraints on magnet systems of future tokamaks based on experiences of present s.c. magnet development

    International Nuclear Information System (INIS)

    Heinz, W.; Jeske, U.; Komarek, P.; Krauth, H.

    1983-01-01

    In view of the urgent need for superconductivity in the next generation of big fusion devices and the identified gap between aimed data and the state of the art, impressive development programs are running world-wide, e.g. the IEA-Large Coil Task (LCT) and magnets for near term experiments (T15, Tore Supra). During the development work for all these magnet systems and simultaneously running design studies, especially the INTOR-study, some critical problem areas, e.g. concerning NbTi-conductor design and manufacturing and coil fabrication could be solved, others like the limitations by fatigue stresses for coil case and support structure turned out to be more stringent than anticipated. This paper tries to show which plasma physics parameters place especially severe constraints to magnet design, like PF-pulse number and amplitude at the TF-coils, so that they should be chosen with strongest care. It further points out which technologies under these circumstances are still missing or unproven with respect to the INTOR-like generation of fusion experiments. Further effort is mainly required for fatigue load behaviour of materials and components, high field windings and poloidal field coils. (author)

  17. The history, development and the present status of the radon measurement programme in the United States of America

    International Nuclear Information System (INIS)

    George, A.C.

    2015-01-01

    The US radon measurement programme began in the late 1950's by the US Public Health Service in Colorado, New Mexico and Utah during the uranium frenzy. After the 1967 Congressional Hearings on the working conditions in uranium mines, the US Atomic Energy Commission (AEC) was asked to conduct studies in active uranium mines to assess the exposure of the miners on the Colorado Plateau and in New Mexico. From 1967 to 1972, the Health and Safety Laboratory of the US AEC in New York investigated more than 20 uranium mines for radon and radon decay product concentrations and particle size in 4 large uranium mines in New Mexico. In 1970, the US Environmental Protection Agency (EPA) was established and took over some of the AEC radon measurement activities. Between 1975 and 1978, the Environmental Measurements Laboratory of the US Department of Energy conducted the first detailed indoor radon survey in the USA. Later in 1984, the very high concentrations of radon found in Pennsylvania homes set the wheels in motion and gave birth to the US Radon Industry. The US EPA expanded its involvement in radon issues and assumed an active role by establishing the National Radon Proficiency Program to evaluate the effectiveness of radon measurement and mitigation methods. In 1998, due to limited resources EPA privatised the radon programme. This paper presents a personal perspective of past events and current status of the US radon programme. It will present an update on radon health effects, the incidence rate of lung cancer in the USA and the number of radon measurements made from 1988 to 2013 using short-term test methods. More than 23 million measurements were made in the last 25 y and as a result more than 1.24 million homes were mitigated successfully. It is estimated that <2 % of the radon measurements performed in the USA are made using long-term testing devices. The number of homes above the US action level of 148 Bq m -3 (4 pCi l -1 ) may be ∼8.5 million because ∼50

  18. The history, development and the present status of the radon measurement programme in the United States of America.

    Science.gov (United States)

    George, A C

    2015-11-01

    The US radon measurement programme began in the late 1950s by the US Public Health Service in Colorado, New Mexico and Utah during the uranium frenzy. After the 1967 Congressional Hearings on the working conditions in uranium mines, the US Atomic Energy Commission (AEC) was asked to conduct studies in active uranium mines to assess the exposure of the miners on the Colorado Plateau and in New Mexico. From 1967 to 1972, the Health and Safety Laboratory of the US AEC in New York investigated more than 20 uranium mines for radon and radon decay product concentrations and particle size in 4 large uranium mines in New Mexico. In 1970, the US Environmental Protection Agency (EPA) was established and took over some of the AEC radon measurement activities. Between 1975 and 1978, the Environmental Measurements Laboratory of the US Department of Energy conducted the first detailed indoor radon survey in the USA. Later in 1984, the very high concentrations of radon found in Pennsylvania homes set the wheels in motion and gave birth to the US Radon Industry. The US EPA expanded its involvement in radon issues and assumed an active role by establishing the National Radon Proficiency Program to evaluate the effectiveness of radon measurement and mitigation methods. In 1998, due to limited resources EPA privatised the radon programme. This paper presents a personal perspective of past events and current status of the US radon programme. It will present an update on radon health effects, the incidence rate of lung cancer in the USA and the number of radon measurements made from 1988 to 2013 using short-term test methods. More than 23 million measurements were made in the last 25 y and as a result more than 1.24 million homes were mitigated successfully. It is estimated that USA are made using long-term testing devices. The number of homes above the US action level of 148 Bq m(-3) (4 pCi l(-1)) may be ∼8.5 million because ∼50 million homes were added since 1990 to the home

  19. Primary mediastinal synovial sarcoma with subsequent development of primary adenoid cystic carcinoma of lung presenting as superior vena cava syndrome.

    Science.gov (United States)

    Madabhavi, Irappa; Patel, Apurva; Anand, Asha; Panchal, Harsha; Parikh, Sonia

    2018-01-01

    Primary mediastinal sarcomas are aggressive tumors with a very rare incidence. This report describes the case of a 35 year old male patient who presented with acute symptoms of dyspnoea, facial puffiness, engorged neck veins and hoarseness of voice. With the clinical picture consistent with the superior vena caval (SVC) syndrome, the patient was investigated with computed tomography of the chest. This revealed a large soft tissue density mass lesion compressing the SVC along with other critical superior mediastinal structures. Histopathological evaluation of the mass revealed features consistent with a soft tissue sarcoma and positive staining was observed for vimentin and S-100. Cytogenetic analysis by fluorescent in-situ hybridization (FISH) demonstrated the t(X: 18) translocation. Thus diagnosis was established as primary mediastinal synovial sarcoma. Patient was treated with three-cycles of neo-adjuvant (ifosfamide 2400mg/m2 on days 1-5 and doxorubicin 37.5 mg/m2 on days 1 & 2) chemotherapy, to which there was a partial response as per the RECIST criteria. Surgical excision of the mediastinal mass was performed, and further post-operative treatment with adjuvant chemo-radiotherapy was provided. Patient was under regular surveillance at our clinic and remains free of symptoms one-year after treatment completion. But after 14 months of treatment completion patient again had symptoms of progressive dyspnea, hoareness of voice and mild facial puffiness over a period of 2 months. On further investigating he was found to have right-sided centrally located mass with cystic and necrotic changes with extension and compression of trachea, SVC, right upper lobe bronchus and its branches. Histopathological examination of the biopsy from the lesion revealed adenoid cystic carcinoma of the lung. Rest of the metastatic work up was within normal. Immunohistochemistry of the specimen revealed c-Kit positivity. In view of the morbid second surgery he was put on Imatinib 400mg

  20. Table of contents, structure and methodical providing of preparation of future trainers-teachers to development of professional presentations of educational material

    Directory of Open Access Journals (Sweden)

    Svatyev А.V.

    2012-03-01

    Full Text Available In the article maintenance, structure and methodical providing of preparation of future trainers-teachers to development of professional presentations of educational material is analysed. The authors approach near lining up the stages of work with students in relation to the input of information technologies in an educational process is offered. The variants of combination of the program of studies and methodical providing of scientific process of future specialists are thoroughly considered. 100 respondents-students of 4 and 5 courses of physical education department were polled. A term "presentation" is exposed, it kinds are certain and classification of presentations is offered. Modern technologies of development of presentation are analysed.

  1. The development of the Ptolemais lignite deposit, present situation and future perspective of the electrical energy market (Greece)

    International Nuclear Information System (INIS)

    Kavourides, Kostas

    1997-01-01

    PPC is by far the major producer of solid fuels in Greece. Currently the known exploitable reserves of solid fuels, are 4,0 billions tones of lignite and 4 billion cubic meters of peat. Mining of Lignite in Greece started in 1951 at the Aliveri underground mine and was continued at the open cast mines at Ptolemais (1955) and Megalopolis (1919). For more than 45 years. PPC has successfully exploited the Greece Lignite deposit for the production of electricity in order to satisfy the demand in Greece. Today PPC produces 60 million tons of lignite and handles approximately 275 million cubic meters of masses (overburden, lignite and interculated) per year. Lignite is the main energy resource in Greece and its combustion provides 75-80% of the electrical energy consumed in Greece.The Lignite Center of Ptolemais - Amyndeon (LCP-A) operated by the Greece PPC is located in northern Greece, about 110 km west of the city of Thessaloniki. The lignite deposits under exploitation cover an area. of 120 km 2 including 4000 Mt of proven geological reserves and 2700 Mt of exploitable lignite under current economic and technological criteria. Today LCP-A manages six active mines which in 1997 have a rate of handling 245 mil cubic meter of material and producing approx. 48 mil for of lignite. The continuous mining method which employs BWES, conveyors and strackers is the principal mining method used in all the lignite mines at the Ptolemais-Amyndeon Lignite Center. The implementation of selective mining procedures as well as discontinuous and /or combined mining methods differentiates the mining technology at the LCP-A from the respective technology applied in Germany lignite mines. The quality properties suggest that the lignite deposits in Greece are among the world's worst quality deposits exploited for energy production, where approximately 2 kg of lignite are consumed per I kWh of generated power. The main advantages of PPC'S coal orientated development program are the following

  2. Present status and approaches for the sustainable development of community based fish culture in seasonal floodplains of Bangladesh.

    Science.gov (United States)

    Rahman, M F; Jalal, K C A; Jahan, Nasrin; Kamaruzzaman, B Y; Ara, R; Arshad, A

    2012-06-15

    Coordination among the different stakeholders at policy planning, implementation and target beneficiary level, particularly among the agencies responsible for development and management of water resources, agriculture and fisheries, is essential for overall sustainable development. Stocking of larger fingerlings at suitable stocking densities of endemic (rohu, catla, mrigal) and exotic (silver carp, bighead carp, common carp/mirror carp) species should be stocked at varying proportion. Floodplain fish production depends only on the natural fertility of the water bodies. Technological interventions should include the installation of low cost bamboo fencing at water inlet and outlet points and setting of ring culverts for maintaining suitable levels of water for fish culture without hampering the production of rice and other crops in the intervention areas, selective stocking with native and exotic carps, restricted fishing for certain period of time and guarding. It is expected to exert positive influences in enhancing the standing crop and biodiversity of non-stocked species of fishes in the intervention seasonal floodplain. Entry of fish larvae, hatchlings and young fry of wild non-stocked fishes into the seasonal floodplains because of large fence spacing (approximately 1.0 cm), could restrict fishing for certain period, undisturbed habitat and guarding could contribute to higher productivity and enhancement of fish biodiversity in the seasonal floodplains. Proper motivation and effective cooperation of the beneficiaries are extremely important to culture fish in the seasonal floodplains under community based management system. Institutional support and constant vigilance from the Department of Fisheries (DoF) and local administrations are indispensable to ensure the sustainability of fish culture initiatives in the seasonal floodplains. Active participation and involvement of the local community people in all stages of fish culture operation beginning from

  3. Development and application of a robust speciation method for determination of six arsenic compounds present in human urine.

    Science.gov (United States)

    Milstein, Lisa S; Essader, Amal; Pellizzari, Edo D; Fernando, Reshan A; Raymer, James H; Levine, Keith E; Akinbo, Olujide

    2003-03-01

    Six arsenic species [arsenate, arsenite, arsenocholine, arsenobetaine, monomethyl arsonic acid, and dimethyl arsinic acid] present in human urine were determined using ion-exchange chromatography combined with inductively coupled plasma mass spectrometry (IC-ICP-MS). Baseline separation was achieved for all six species as well as for the internal standard (potassium hexahydroxy antimonate V) in a single chromatographic run of less than 30 min, using an ammonium carbonate buffer gradient (between 10 and 50 mM) at ambient temperature, in conjunction with cation- and anion-exchange columns in series. The performance of the method was evaluated with respect to linearity, precision, accuracy, and detection limits. This method was applied to determine the concentration of these six arsenic species in human urine samples (n = 251) collected from a population-based exposure assessment survey. Method precision was demonstrated by the analysis of duplicate samples that were prepared over a 2-year analysis period. Total arsenic was also determined for the urine samples using flow injection analysis coupled to ICP-MS. The summed concentration of the arsenic species was compared with the measured arsenic total to demonstrate mass balance.

  4. Graphics processor unit acceleration enables realtime endovascular Doppler optical coherence tomography imaging: development and validation (Conference Presentation)

    Science.gov (United States)

    Barrows, Dexter; Ramjist, Joel M.; Vuong, Barry; Lee, Kenneth K.; Jivraj, Jamil; Yang, Victor X. D.

    2017-02-01

    Endovascular Optical Coherence Tomography (OCT) has previously been used in both bench-top and clinical environments to produce vascular images, and can be helpful in characterizing, among other pathologies, plaque build-up and impedances to normal blood flow. The raw data produced can also be processed to yield high-resolution blood velocity information, but this computation is expensive and has previously only been available a posteriori using post-processing software. Real-time Doppler OCT (DOCT) imaging has been demonstrated before in the skin and eye, but this capability has not been available to vascular surgeons. Graphics Processing Units (GPUs) can be used to dramatically accelerate this type of distributed computation. In this paper we present a software package capable of real-time DOCT processing and circular image display using GPU acceleration designed to operate with catheter-based clinical OCT systems. This image data is overlayed onto structural images providing clinicians with live, high-resolution blood velocity information to complement anatomical data. Further, we validated flow data obtained in real time using a carotid flow phantom - constructed using 3D structural OCT data - and controlled flow from an external pump.

  5. The United Nations Population Fund and Planned Parenthood proudly present the International Conference on Population and Development.

    Science.gov (United States)

    Corey, W

    1994-01-01

    The 1994 International Conference on Population and Development (ICPD) was orchestrated and largely controlled by such pro-choice groups as the UN Population Fund, Planned Parenthood, and radical American feminists. Efforts to promote abortion in parts of the world where it is illegal were couched in such terms as "safe motherhood" and "reproductive health." These efforts failed, however, with inclusion of the clause stating that abortion shall not be promoted as a means of family planning. However, the seeds of abortion, in the form of unnatural contraception, continue to be spread throughout the world. On the other hand, in the nongovernmental organization forum, which ran concurrently with the ICPD, pro-life organizations attracted a great deal of attention at the International Right to Life Federation booth. A workshop on natural family planning was attended by only a few people, but interest was high and the attendees followed-up by requesting more information during the Forum. A press conference held by Catholics for a Free Choice backfired because the mostly Moslem audience left angry at the women's apparent lack of obedience to the Pope. Other American feminists were confronted with the sight of women from the Third World picketing the conference with signs like "2 cars for every family in the North; one child for every family in the South." The pro-choice activists succeeded in bolstering the esteem of the Pope by making it evident that he is carrying the burden of family values almost singlehandedly.

  6. Content Development, Presentation and Delivery for eLearning in Nuclear Science and Engineering: Experiences with Emerging Authoring Tools

    International Nuclear Information System (INIS)

    Bamford, S.; Afriyie, P.; Comlan, E.

    2016-01-01

    Full text: Transference of explicit knowledge starts from content development, and proceeds with packaging and delivery. A comparative study of some selected authoring tools for knowledge creation in Nuclear Sciences and Engineering education is being carried out at the School of Nuclear and Allied Sciences in Accra, Ghana. These authoring tools include commercial software (Macromedia Suite CS6, Learning 6.0) as well as freeware software (Xerte, eXe). A course, X-ray Fluorescence Spectrometry (NSAP 603), at the postgraduate School of Nuclear and Allied Sciences (SNAS), has been selected for migration onto an eLearning platform. Different authoring tools have been employed to create some ICT-based modules for teaching and learning. This paper therefore shares the experiences realized in moving from course syllabus to digitized modules, integrating pedagogical considerations, the strengths and weakness of the selected authoring tools, user-interactivity and usability of the modules produced. The need and the basis for the adoption of an appropriate authoring tool for creation of scientific, mathematical, and engineering documents and learning materials has also been discussed. Leveraging on ICT to produce pedagogically sound learning materials for eLearning platforms promotes interests of students in nuclear sciences, and ensures continuity in producing qualified professionals. (author

  7. Genetic engineering to develop salt tolerance in potato: a need of the present time scenario(abstract)

    International Nuclear Information System (INIS)

    Ikram ul Haq; Dahot, M.U.

    2005-01-01

    Of environmental stresses, salinity has negative impacts on agricultural yield throughout the world; affected production is 1% as compared to 3%. Soil salinity affects plant growth and development by way of osmotic stress, injurious effects of toxic Na/sup +/ and Cl/sup -/ ions and to some extent Cl/sup -/ and SO/sub 4//sup 2-/ of Mg//sup 2+/. The plant response to salinity consists of numerous processes that must function in coordination to alleviate both cellular hyper osmolarity and ion disequilibrium. However, cell biology and molecular genetics research is providing new insight into the plant response to salinity and is identifying genetic determinants involved in the salt tolerance. Recent confirmation (Arabidopsis thaliana) to salt tolerance determinants is that mediate cellular ion homeostasis. The transport systems facilitate cellular capacity to utilize Na/sup +/ for osmotic adjustment and growth and the role of the Salt-Overly-Sensitive (SOS) signal transduction pathway in the regulation of ion homeostasis and salt tolerance. The SOS signaling pathway regulates Na/sup +/ and K/sup +/ homeostasis, after Ca/sup 2+/ activation. Furthermore, overexpression of AtNHX1 enhances plant salt tolerance, presumably by increasing vacuolar Na/sup +//H/sup +/ compartmentalization that minimizes the toxic I. accumulation of the ion in the cytosol. The activation of SOS1 (Na/sup +/ efflux) and/or AtNHX1 (Na/sup +/ efflux) so by expression of such transporters enhances salt tolerance in plants. (author)

  8. Economic burden of torture for a refugee host country: development of a model and presentation of a country case study

    Science.gov (United States)

    Mpinga, Emmanuel Kabengele; Frey, Conrad; Chastonay, Philippe

    2014-01-01

    Background Torture is an important social and political problem worldwide that affects millions of people. Many host countries give victims of torture the status of refugee and take care of them as far as basic needs; health care, professional reinsertion, and education. Little is known about the costs of torture. However, this knowledge could serve as an additional argument for the prevention and social mobilization to fight against torture and to provide a powerful basis of advocacy for rehabilitation programs and judiciary claims. Objectives Development of a model for estimating the economic costs of torture and applying the model to a specific country. Methods The estimation of the possible prevalence of victims of torture was based on a review of the literature. The identification of the socioeconomic factors to be considered was done by analogy with various health problems. The estimation of the loss of the productivity and of the economic burden of disease related to torture was done through the human capital approach and the component technique analysis. Case study The model was applied to the situation in Switzerland of estimated torture victims Switzerland is confronted with. Results When applied to the case study, the direct costs – such as housing, food, and clothing – represent roughly 130 million Swiss francs (CHF) per year; whereas, health care costs amount to 16 million CHF per year, and the costs related to education of young people to 34 million CHF per year. Indirect costs, namely those costs related to the loss of the productivity of direct survivors of torture, have been estimated to one-third of 1 billion CHF per year. This jumps to 10,073,419,200 CHF in the loss of productivity if one would consider 30 years of loss per survivor. Conclusion Our study shows that a rough estimation of the costs related to torture is possible with some prerequisites, such as access to social and economic indicators at the country level. PMID:24729721

  9. Influence of HIV and HCV on T cell antigen presentation and challenges in the development of vaccines

    Directory of Open Access Journals (Sweden)

    Mina eJohn

    2014-10-01

    Full Text Available Some of the central challenges for developing effective vaccines against HIV and hepatitis C virus (HCV are similar. Both infections are caused by small, highly mutable, rapidly replicating RNA viruses with the ability to establish long-term chronic pathogenic infection in human hosts. HIV has caused 60 million infections globally and HCV 180 million and both viruses may co-existent among certain populations by virtue of common blood-borne, sexual or vertical transmission. Persistence of both pathogens is achieved by evasion of intrinsic, innate and adaptive immune defenses but with some distinct mechanisms reflecting their differences in evolutionary history, replication characteristics, cell tropism and visibility to mucosal versus systemic and hepatic immune responses. A potent and durable antibody and T cell response is a likely requirement of future HIV and HCV vaccines. Perhaps the single biggest difference between the two vaccine design challenges is that in HCV, a natural model of protective immunity can be found in those who resolve acute infection spontaneously. Such spontaneous resolvers exhibit durable and functional CD4+ and CD8+ T cell responses. However frequent re-infection suggests partial or lack of protective immunity against heterologous HCV strains, possibly indicative of the degree of genetic diversity of circulating HCV genotypes and subtypes. There is no natural model of protective immunity in HIV, however studies of elite controllers, or individuals who have durably suppressed levels of plasma HIV RNA without antiretroviral therapy has provided the strongest evidence for CD8+ T cell responses in controlling viremia and limiting reservoir burden in established infection. Here we compare and contrast the specific mechanisms of immune evasion used by HIV and HCV, which subvert adaptive human leucocyte antigen (HLA-restricted T cell immunity in natural infection, and the challenges these pose for designing effective

  10. Presenting Triple-Wins? Assessing Projects That Deliver Adaptation, Mitigation and Development Co-benefits in Rural Sub-Saharan Africa

    OpenAIRE

    Suckall, Natalie; Stringer, Lindsay C.; Tompkins, Emma L.

    2014-01-01

    The concept of climate compatible development (CCD) is increasingly employed by donors and policy makers seeking 'triple-wins' for development, adaptation and mitigation. While CCD rhetoric is becoming more widespread, analyses drawing on empirical cases that present triple-wins are sorely lacking. We address this knowledge gap. Drawing on examples in rural sub-Saharan Africa, we provide the first glimpse into how projects that demonstrate triple-win potential are framed and presented within ...

  11. Workshop presentations

    International Nuclear Information System (INIS)

    Sanden, Per-Olof; Edland, Anne; Reiersen, Craig; Mullins, Peter; Ingemarsson, Karl-Fredrik; Bouchard, Andre; Watts, Germaine; Johnstone, John; Hollnagel, Erik; Ramberg, Patric; Reiman, Teemu

    2009-01-01

    An important part of the workshop was a series of invited presentations. The presentations were intended to both provide the participants with an understanding of various organisational approaches and activities as well as to stimulate the exchange of ideas during the small group discussion sessions. The presentation subjects ranged from current organisational regulations and licensee activities to new organisational research and the benefits of viewing organisations from a different perspective. There were more than a dozen invited presentations. The initial set of presentations gave the participants an overview of the background, structure, and aims of the workshop. This included a short presentation on the results from the regulatory responses to the pre-workshop survey. Representatives from four countries (Sweden, Canada, Finland, and the United Kingdom) expanded upon their survey responses with detailed presentations on both regulatory and licensee safety-related organisational activities in their countries. There were also presentations on new research concerning how to evaluate safety critical organisations and on a resilience engineering perspective to safety critical organisations. Below is the list of the presentations, the slides of which being available in Appendix 2: 1 - Workshop Welcome (Per-Olof Sanden); 2 - CSNI Working Group on Human and Organisational Factors (Craig Reiersen); 3 - Regulatory expectations on justification of suitability of licensee organisational structures, resources and competencies (Anne Edland); 4 - Justifying the suitability of licensee organisational structures, resources and competencies (Karl-Fredrik Ingemarsson); 5 - Nuclear Organisational Suitability in Canada (Andre Bouchard); 6 - Designing and Resourcing for Safety and Effectiveness (Germaine Watts); 7 - Organisational Suitability - What do you need and how do you know that you've got it? (Craig Reiersen); 8 - Suitability of Organisations - UK Regulator's View

  12. Papers presented at the IAEA specialists' meeting on the development of an international nuclear decay data and cross-section database

    International Nuclear Information System (INIS)

    Lemmel, H.D.

    1994-12-01

    The present report contains 20 papers presented at the IAEA meeting on the Development of an International Nuclear Decay Data and Cross-Section Database, Vienna, 24-28 October 1994, covering the following topics: Wall-charts of nuclides, PC systems presenting nuclear data, nuclear decay-data and uncertainties, nuclear spectroscopy, thermal neutron cross-sections and resonance-integrals, reactor-neutron activation analysis, nuclear data standards. (author). Refs, figs and tabs

  13. CERN presentations

    CERN Multimedia

    CERN. Geneva

    2011-01-01

    Presentation by CERN (10 minutes each) Rolf Landua - Education and Outreach Salvatore Mele - Open Access Jean-Yves Le Meur - Digital Library in Africa Francois Fluckiger - Open Source/Standards (tbc) Tim Smith - Open Data for Science Tullio Basiglia - tbc

  14. Motor development profile in 9-11 year-old children from the municipal education system of Maceio, Alagoas State, presenting low school performance

    Directory of Open Access Journals (Sweden)

    Maria Natália Santos da Silva

    2014-04-01

    Full Text Available Introduction: Children may present motor development delays that can influence their learning process, hence the need for specific assessment for the early detection of such delays in an attempt to resolve or mitigate possible future damage. Objective: Profile of motor development in children aged 9-11 years old presenting low academic achievement in the municipal education system of Maceio, Alagoas state. Methodology: An exploratory, descriptive, transversal study which uses the Motor Development Scale (MDS to analyze the main components of performance. Evaluations were carried out with 43 children of both genders. Results: The children assessed presented motor profiles ranging from “normal” to “far below average”, corroborating the findings in the literature. Conclusions: The results obtained are in agreement with the literature, showing a close relation between motor development and low school performance, emphasizing the importance of psychomotor intervention for the maturation of more complex motor patterns.

  15. Lecture Presentations

    International Nuclear Information System (INIS)

    2008-01-01

    The Symposium on Physics of Elementary Interactions in the LHC Era held in Warsaw from 21 to 22 April 2008. The main subject of the workshop was to present the progress in CERN LHC collider project. Additionally some satellite activities in field of education, knowledge and technology transfer in the frame of CERN - Poland cooperation were shown

  16. Voting Present

    Directory of Open Access Journals (Sweden)

    James Lo

    2013-12-01

    Full Text Available During his time as a state senator in Illinois, Barack Obama voted “Present” 129 times, a deliberate act of nonvoting that subsequently became an important campaign issue during the 2008 presidential elections. In this article, I examine the use of Present votes in the Illinois state senate. I find evidence that Present votes can largely be characterized as protest votes used as a legislative tool by the minority party. Incorporating information from Present votes into a Bayesian polytomous item-response model, I find that this information increases the efficiency of ideal point estimates by approximately 35%. There is little evidence of significant moderation by Obama when Present votes are accounted for, though my results suggest that Obama’s voting record may have moderated significantly before his subsequent election to the U.S. Senate. My results also suggest that because legislative nonvoting may occur for a variety of reasons, naive inclusion of nonvoting behavior into vote choice models may lead to biased results.

  17. Workshop presentation.

    Science.gov (United States)

    2013-12-01

    On December 18, 2013, the research team hosted a workshop at CTR to gather feedback on and : generate discussion of the mode choice model that was developed. : Attendees included the project monitoring committee (PMC) and TTI personnel who staff a he...

  18. Technical presentation

    CERN Multimedia

    FI Department

    2008-01-01

    RADIOSPARES, the leading catalogue distributor of components (electronic, electrical, automation, etc.) and industrial supplies will be at CERN on Friday 3 October 2008 (Main Building, Room B, from 9.00 a.m. to 3.00 p.m.) to introduce its new 2008/2009 catalogue. This will be the opportunity for us to present our complete range of products in more detail: 400 000 part numbers available on our web site (Radiospares France, RS International, extended range of components from other manufacturers); our new services: quotations, search for products not included in the catalogue, SBP products (Small Batch Production: packaging in quantities adapted to customers’ requirements); partnership with our focus manufacturers; demonstration of the on-line purchasing tool implemented on our web site in conjunction with CERN. RADIOSPARES will be accompanied by representatives of FLUKE and TYCO ELECTRONICS, who will make presentations, demonstrate materials and answer any technical questio...

  19. Presentations provided

    International Nuclear Information System (INIS)

    Hashemian, H.; Beverly, D.

    1998-01-01

    The following topics covered in detail at the workshop included: temperature instrumentation; pressure instrumentation; in-situ calibration and response time testing of RTDs and pressure transmitters; on-line performance monitoring and preventive maintenance of critical equipment; automated measurement of critical parameters; nuclear power plant infrastructure, management and Quality Assurance issues and recent developments for WWER and RBMK reactors. Conclusions drawn were: aging can adversely affect the performance of nuclear plant pressure transmitters; current testing interval of once in every fuel cycle is adequate for aging management; in-situ response time measurements and on-line calibration testing methods have been developed and validated for nuclear plant pressure transmitters; NUREG/CR-5851 should be taken into account for details of aging research on pressure transmitters

  20. Technical presentation

    CERN Multimedia

    FP Department

    2009-01-01

    07 April 2009 Technical presentation by Leuze Electronics: 14.00 – 15.00, Main Building, Room 61-1-017 (Room A) Photoelectric sensors, data identification and transmission systems, image processing systems. We at Leuze Electronics are "the sensor people": we have been specialising in optoelectronic sensors and safety technology for accident prevention for over 40 years. Our dedicated staff are all highly customer oriented. Customers of Leuze Electronics can always rely on one thing – on us! •\tFounded in 1963 •\t740 employees •\t115 MEUR turnover •\t20 subsidiaries •\t3 production facilities in southern Germany Product groups: •\tPhotoelectric sensors •\tIdentification and measurements •\tSafety devices

  1. Annual Proceedings of Selected Research and Development Papers Presented at the Annual Convention of the Association for Educational Communications and Technology (31st, Orlando, FL, 2008)

    Science.gov (United States)

    Simonson, Michael, Ed.

    2008-01-01

    For the thirty-first year, the Research and Theory Division of the Association for Educational Communications and Technology (AECT) sponsored the publication of these Proceedings. Papers were presented at the annual AECT Convention in Orlando, Florida. This year's Proceedings has two sections--Section 1 includes research and development papers and…

  2. Professional presentations made simple.

    Science.gov (United States)

    Starver, Kelly D; Shellenbarger, Teresa

    2004-01-01

    One way clinical nurse specialists (CNS) influence nursing practice and share professional expertise is by making presentations. This article presents strategies that clinical nurse specialists can use to enhance the effectiveness of oral presentations. Included are tips for analyzing the audience, developing content and materials, selecting presentation methods, and delivering an effective presentation.

  3. Study of the development of solar energy in Rhone-Alpes. Presentation of the photovoltaic sector, Presentation of the solar thermal sector, Sunshine mapping, Assessment of installations by the end 2009, Development potential for solar thermal energy, Development potential for solar photovoltaic energy

    International Nuclear Information System (INIS)

    2010-12-01

    A first part proposes a wide presentation of the photovoltaic sector with an overview of largest plants, a market analysis (on the 2001-2009 period in the World, Europe and France, per technology, in terms of industrial tissue and R and D activity in France, evolution per region and per technology), a presentation of the different technologies (from the first to the third generation, in terms of costs, and of perspective for the different sectors), an environmental assessment of the different sectors (CO 2 emissions and avoided emissions), a presentation of the main actors of the photovoltaic sector (silicon producers, cell producers, thin layer producers, developers), a presentation of tracking technologies (trackers gains), and a perspective for the photovoltaic sector in Europe and in the World. In a same way, a second part presents the solar thermal sector: market analysis, active and passive technologies, solar concentration technology, environmental assessment, future perspective in Europe and in the World. A sunshine mapping is then proposed for the Rhone-Alpes region. The next part discusses various stakes: regulation for roof-based installations and for ground-based photovoltaic plants with respect to various issues (land planning, environment, biodiversity, agriculture, landscape, cultural heritage, natural risks). The next part proposes an assessment of solar thermal and photovoltaic installations at the end of 2009

  4. Chronic Subdural Hematoma development in Accelerated phase of Chronic Myeloid Leukaemia presenting with seizure and rapid progression course with fatal outcome

    Directory of Open Access Journals (Sweden)

    Raheja Amol

    2015-06-01

    Full Text Available Occurrence of chronic subdural hematoma (CSDH in leukemia is rare, and most reported cases occurred in relation with acute myeloid leukaemia; however, occurrence is extremely rare in accelerated phase of chronic myelogenous leukaemia (CML. Seizure as presentation of SDH development in CML cases is not reported in literature. Authors report an elderly male, who was diagnosed as CML, accelerated phase of developing SDH. Initially presented to local physician with seizure; urgent CT scan head was advised, but ignored and sensorium rapidly worsened over next day and reported to our emergency department in deeply comatose state, where imaging revealed chronic subdural hematoma with hypoxic brain injury with fatal outcome. Seizure, progressive worsening of headache, vomiting and papilloedema are harbinger of intracranial space occupying lesion and requires CT head in emergency medical department for exclusion, who are receiving treatment of haematological malignancy

  5. Hydrocephalus presenting as idiopathic aqueductal stenosis with subsequent development of obstructive tumor: report of 2 cases demonstrating the importance of serial imaging.

    Science.gov (United States)

    Roland, Jarod L; Price, Richard L; Kamath, Ashwin A; Akbari, S Hassan; Leuthardt, Eric C; Miller, Brandon A; Smyth, Matthew D

    2017-10-01

    The authors describe 2 cases of triventricular hydrocephalus initially presenting as aqueductal stenosis that subsequently developed tumors of the pineal and tectal region. The first case resembled late-onset idiopathic aqueductal stenosis on serial imaging. Subsequent imaging revealed a new tumor in the pineal region causing mass effect on the midbrain. The second case presented in a more typical pattern of aqueductal stenosis during infancy. On delayed follow-up imaging, an enlarging tectal mass was discovered. In both cases hydrocephalus was successfully treated by cerebrospinal fluid diversion prior to tumor presentation. The differential diagnoses, diagnostic testing, and treatment course for these unusual cases are discussed. The importance of follow-up MRI in cases of idiopathic aqueductal stenosis is emphasized by these exemplar cases.

  6. REVIEW APPROACHES ECONOMIC DEVELOPMENT OF THE TERRITORY OF THE ARCTIC ZONE OF THE RUSSIAN FEDERATION, PRESENTED IN THE FORM OF TARGET SUBSPACE

    Directory of Open Access Journals (Sweden)

    N. I. Didenko

    2015-01-01

    Full Text Available This paper presents a conceptual idea of the organization of management of development of the Arctic area of the Russian Federation in the form of a set of target subspace. Among the possible types of target subspace comprising the Arctic zone of the Russian Federation, allocated seven subspace: basic city mobile Camps, site production of mineral resources, recreational area, fishing area, the Northern Sea Route, infrastructure protection safe existence in the Arctic. The task of determining the most appropriate theoretical approach for the development of each target subspaces. To this end, the theoretical approaches of economic growth and development of the theory of "economic base» (Economic Base Theory; resource theory (Staple Theory; Theory sectors (Sector Theory; theory of growth poles (Growth Pole Theory; neoclassical theory (Neoclassical Growth Theory; theory of inter-regional trade (Interregional Trade Theory; theory of the commodity cycle; entrepreneurial theory (Entrepreneurship Theories.

  7. NITRD Presentation Library

    Data.gov (United States)

    Networking and Information Technology Research and Development, Executive Office of the President — This resource is a collection of presentations, reports, and webinars given by a broad range of presenters from academia, government, and private sectors at various...

  8. Present state of new technologies of nuclear power generation, and technological development of fast-breeder reactor and next-generation light water reactor

    International Nuclear Information System (INIS)

    Aoyagi, Toshihiro; Ando, Masato

    2014-01-01

    This paper introduces the present state of development of FBR in Japan and international cooperation, the development of HP-ABWR and HP-APWR as the next-generation light water reactors, and SMR development in the United States. As for FBR, the following situations are described: (1) history of development in Japan in the past, (2) history of change due to the readjustment of development plan caused by the accident of Fukushima Daiichi Nuclear Power Station, in which shift to FaCT phase 2 was suspended, and the approach to the establishment of safety standards for sodium-cooled FBR and its international standardization was adopted, and (3) future challenges. As for the Japan - France fast-breeder reactor development cooperation, the conclusion of the Japan - France inter-government agency agreement, and Japan's cooperation plan and system are described. Next, as for HP-ABWR and HP-APWR, the development goal and concept of each plant, and the element technologies required for the success are described. On the other hand, the small reactor development in the United States started with the aim of the securement of domestic technology base, contribution to reduction in carbon dioxide emissions, and its export to new entry countries for nuclear energy. This project aimed the practical use of SMR, and started 'financial support program for small reactors' to allocate about 452 million dollars to maximum two units of SMRs in the next five years. This project is outlined. (A.O.)

  9. Opinion presented on behalf of the Economical Affairs Commission on the finance bill for 2010 (n. 1946) - Volume II: Sustainable ecology, development and planning. Industry and energy

    International Nuclear Information System (INIS)

    2009-10-01

    This report of the French National Assembly first presents the different programmes and actions related to energy and industry for which credits are foreseen in the French finance bill for 2010: development of firms and employment, energy policy, after-mining policy, struggle against climate change, management of ecology, energy, sustainable development, and sea policies, research in the field of energy and sustainable development and planning. The author then outlines the importance of the creation of conditions for a green growth in order to cope with an unprecedented crisis which ruins industrial employment. This implies the support of strategic sectors (energy-efficient building, evolution towards green chemistry, photovoltaic solar energy, renewable heat, innovating vehicles), the implementation of new priorities (smart grids, management of raw materials), and the emergence of ecological technologies promoted by the new tools of a climate policy (carbon tax introduction, improvement of carbon markets). It also implies an industrial output for research by means of a networking of actors (development of competitiveness poles, participation to European partnerships), and a reinforcement of the industrial horizon in the research policy (patenting, start-up development, support to innovating small and middle-sized companies, implementation of a true French capital-risk sector)

  10. Forkhead Box O1 is present in quiescent pituitary cells during development and is increased in the absence of p27 Kip1.

    Directory of Open Access Journals (Sweden)

    Sreeparna Majumdar

    Full Text Available Congenital pituitary hormone deficiencies have been reported in approximately one in 4,000 live births, however studies reporting mutations in some widely studied transcription factors account for only a fraction of congenital hormone deficiencies in humans. Anterior pituitary hormones are required for development and function of several glands including gonads, adrenals, and thyroid. In order to identify additional factors that contribute to human congenital hormone deficiencies, we are investigating the forkhead transcription factor, FOXO1, which has been implicated in development of several organs including ovary, testis, and brain. We find that FOXO1 is present in the nuclei of non-dividing pituitary cells during embryonic development, consistent with a role in limiting proliferation and/or promoting differentiation. FOXO1 is present in a subset of differentiated cells at e18.5 and in adult with highest level of expression in somatotrope cells. We detected FOXO1 in p27(Kip1-positive cells at e14.5. In the absence of p27(Kip1 the number of pituitary cells containing FOXO1 is significantly increased at e14.5 suggesting that a feedback loop regulates the interplay between FOXO1 and p27(Kip1.

  11. Use of net present value analysis to evaluate a publicly funded biomass-to-ethanol research, development, and demonstration program and valuate expected private sector participation.

    Science.gov (United States)

    Hinman, N D; Yancey, M A

    1998-01-01

    One of the functions of government is to invest tax dollars in programs, projects, and properties that will result in greater public benefit than would have resulted from leaving the tax dollars in the private sector or using them to pay off the public debt. This paper describes the use of Net Present Value (NPV) as an approach to analyze and select investment opportunities for government money in public research, development, and demonstration (RD&D) programs and to evaluate potential private sector participation in the programs. This approach is then applied to a specific biomass-to-ethanol opportunity in California.

  12. Present status in research and development of a multi-purpose high-temperature gas cooled reactor in JAERI. 1985 ed.

    International Nuclear Information System (INIS)

    1985-01-01

    In Japan, it is forecast that the energy demand in the industries consuming large amount of energy, such as iron and steel, paper and pulp, chemicals, ceramics and earth and stones, will decrease due to energy saving and the stagnant demand of those products, whereas mechatronics will largely grow. Accordingly, the demand and supply of whole energy will change. The development of high temperature gas-cooled reactors is highly significant for diversifying and stably ensuring energy resources in Japan. Japan Atomic Energy Research Institute has advanced the research and development of multi-purpose high temperature gas-cooled reactors since 1969, and the main accomplishment carried out so far is briefly reported. The important step in this development is the construction of an experimental reactor, and its preparation is in progress. At present, the rationalizing design of the experimental reactor is carried out, and the construction will begin in fiscal year 1989. In this report, concerning multi-purpose high temperature gas-cooled reactors, the outline of the research and development, the design of the experimental reactor, the research on fuel and graphite, metallic materials, reactor technology, high temperature equipment and structure and others are described. (Kako, I.)

  13. The Activation of Non-evaporable Getters Monitored by AES, XPS, SSIMS and Secondary Electron Yield Measurements

    CERN Document Server

    Scheuerlein, C

    2002-01-01

    In this thesis the potential of the three classical surface analysis techniques Auger electron spectroscopy (AES), X-ray photoelectron spectroscopy (XPS) and static secondary ion mass spectrometry (SSIMS) for the characterisation of non-evaporable getter (NEG) materials is assessed and artefacts are described. The various NEG samples have been analysed in the context of the development of NEG thin film coatings for use in accelerator ultra high vacuum (UHV) systems. The secondary electron yield (SEY), which is a functional surface property of great importance for the application of NEG to accelerators, has been measured. The maximum SEY of an air exposed TiZr and TiZrV coating can be reduced from above 2.0 to below 1.1 during a 2 h heat treatment at 250 and 200 °C, respectively. Saturating an activated TiZrV surface in UHV increases the maximum SEY by about 0.1. Thus, in UHV the SEY of an activated NEG coating does not exceed the threshold value of 1.35, above which multipacting is predicted to occur in th...

  14. The association of plasma oxidative status and inflammation with the development of atrial fibrillation in patients presenting with ST elevation myocardial infarction.

    Science.gov (United States)

    Bas, Hasan Aydin; Aksoy, Fatih; Icli, Atilla; Varol, Ercan; Dogan, Abdullah; Erdogan, Dogan; Ersoy, Ibrahim; Arslan, Akif; Ari, Hatem; Bas, Nihal; Sutcu, Recep; Ozaydin, Mehmet

    2017-04-01

    Atrial fibrillation (AF) is the most common supraventricular arrhythmia following ST elevation myocardial infarction (STEMI). Oxidative stress and inflammation may cause structural and electrical remodeling in the atria making these critical processes in the pathology of AF. In this study, we aimed to evaluate the association between total oxidative status (TOS), total antioxidative capacity (TAC) and high-sensitivity C-reactive protein (hs-CRP) in the development of AF in patients presenting with STEMI. This prospective cohort study consisted of 346 patients with STEMI. Serum TAC and TOS were assessed by Erel's method. Patients were divided into two groups: those with and those without AF. Predictors of AF were determined by multivariate regression analysis. In the present study, 9.5% of patients developed AF. In the patients with AF, plasma TOS and oxidative stress index (OSI) values were significantly higher and plasma TAC levels were significantly lower compared to those without AF (p = .003, p = .002, p atrial diameter (OR =1.28; 95% CI =1.12-1.47; p atrial diameter and hs-CRP.

  15. Gender identity shows a high correlation with Prader score in patients with disorders of sex development (DSD) presenting in mid childhood.

    Science.gov (United States)

    Chowdhury, Tanvir K; Chowdhury, Md Zonaid; Mili, Fahmida; Hutson, John M; Banu, Tahmina

    2014-05-01

    In developing countries like Bangladesh, delayed presentation for disorders of sex development (DSD) is common, and provides some special problems for management. There remains significant controversy about appropriate sex assignment in this group. We aimed, therefore, to assess gender identity (GI) in 50 consecutive patients with DSD presenting to a referral centre in Chittagong, Bangladesh, and correlate it with Prader score, to see if the latter could be used to predict GI. A cross-sectional, case-control study of 50 consecutive children with DSD and 50 children with vascular anomalies was conducted in the Pediatric Surgical Clinic, Chittagong Medical College and Hospital. After informed consent, patients and controls provided oral answers to a GI questionnaire and had a detailed history and physical examination. Sex-typed activities were assessed by observations of a structured toy play and the child's selection of a toy to keep. Both patients and parents then completed the Child Game Participation Questionnaire. There were no differences in age (2-16 years, mean 8.74) between controls and DSD patients (11 46, XX DSD, 32 46, XY DSD, 4 MGD, 3 ovo-testicular DSD). Fifteen of the DSD patients (30 %) came from consanguineous marriages and only 2 of the control patients had consanguinity of their parents. For the 13-question GI interview, there was no overall difference between DSD cases and controls. For the 46, XX DSD subgroup, there was a significantly higher score (11.1 ± 7.1) compared with control girls (4.5 ± 4.7) (p gender-related behaviour correlated with Prader score for DSD patients (r = 0.61) (p gender-role behaviour should be assessed routinely in DSD patients presenting after the neonatal period, so that sex assignment is in accordance with behaviour. Prader scores showed a good correlation with GI and gender role behaviour.

  16. Presentation of the Results from the Project of Making Base Documents for Low-Emission Development Strategy for Croatia Until 2030 with an Outlook to 2050

    International Nuclear Information System (INIS)

    Jelavic, V.; Delija, V.; Herencic, L.

    2016-01-01

    Paris Climate Agreement is United Nations' Framework Convention on Climate Change way of encouraging countries to prepare Low-Emission development strategies and shows that climate change require long-term development strategies that support sustainable development, with the purpose of limiting the increase of global temperature to the maximal 2 degrees Celsius by the end of the century. The starting point of EU's policy towards low-emission economy is a goal of reducing greenhouse gas emissions by 80-95 percent by 2050. In accordance with that goal, The European Council adopted a climate-energy framework 2030 in October 2014, which sets a goal of reducing emissions - 40 percent by 2030. It also sets a goal of renewable energy sources share of up to 27 percent and an indicative goal of reducing energy consumption - 27 percent. At this moment, a process of accepting and consultations for regulatory climate-energy framework is taking part, as well as a change of greenhouse gas market directive, distribution of load on countries regulation and calculations of emissions from the sector of Land use, Land-use Change and Forestry (LULUCF) regulation. In 2015, The Ministry of Environment and Energy has started a project of making base documents for Low-Emission Development Strategy until 2030 with an outlook to 2050. This strategy applies to every economy and human activity sector and is especially linked to energy sector, industrial, transport, agriculture, forestry and waste management sectors. In the process of making base documents for the Strategy, a number of scenarios were analysed, models for simulations and optimisation were applied and an integral model for national greenhouse gas projections was developed. The Strategy outlines three scenarios: Reference scenario represents the application of the existing legislation while the other two scenarios present a transition towards low-emission economy: Gradual Transition Scenario (NU1) and Strong Transition

  17. Delayed Development of Brain Abscesses Following Stent-Graft Placement in a Head and Neck Cancer Patient Presenting with Carotid Blowout Syndrome

    International Nuclear Information System (INIS)

    Oweis, Yaseen; Gemmete, Joseph J.; Chaudhary, Neeraj; Pandey, Aditya; Ansari, Sameer

    2011-01-01

    We describe the delayed development of intracranial abscesses following emergent treatment with a covered stent-graft for carotid blowout syndrome (CBS) in a patient with head and neck cancer. The patient presented with hemoptysis and frank arterial bleeding through the tracheostomy site. A self-expandable stent-graft was deployed across a small pseudoaneurysm arising from the right common carotid artery (RCCA) and resulted in immediate hemostasis. Three months later, the patient suffered a recurrent hemorrhage. CT of the neck demonstrated periluminal fluid around the caudal aspect of the stent-graft with intraluminal thrombus and a small pseudoaneurysm. Subsequently, the patient underwent a balloon test occlusion study and endovascular sacrifice of the RCCA and right internal carotid artery. MRI of the brain demonstrated at least four ring-enhancing lesions within the right cerebral hemisphere consistent with intracranial abscesses that resolved with broad-spectrum antibiotic coverage.

  18. British researchers receive awards for Grid development: Andy McNab of the University of Manchester was presented with a CERN-UK award for outstanding achievement in Grid development

    CERN Document Server

    Maximilien Brice

    2004-01-01

    McNab has made key contributions to developing a robust security model for the Large Hadron Collider Computing Grid. The awards were presented by CERN's director-general, Robert Aymar, during a meeting of GridPP, a collaboration of particle physicists and computing scientists from the UK and CERN.

  19. Presentation skills for nurses.

    Science.gov (United States)

    Foulkes, Mark

    2015-02-20

    This article emphasises the importance of effective presentation skills. Such skills allow nurses to share knowledge and expertise and to communicate clearly in a range of workplace scenarios. Nurses are increasingly being asked to present in formal and informal situations, such as conferences, poster presentations, job interviews, case reports and ward-based teaching. This article explores the principles underpinning the development of these skills, discusses the situations in which they could be applied and demonstrates how nurses might improve and develop as presenters.

  20. Development of an enhanced bovine viral diarrhea virus subunit vaccine based on E2 glycoprotein fused to a single chain antibody which targets to antigen-presenting cells.

    Science.gov (United States)

    Pecora, Andrea; Malacari, Darío A; Pérez Aguirreburualde, María S; Bellido, Demian; Escribano, José M; Dus Santos, María J; Wigdorovitz, Andrés

    2015-01-01

    Bovine viral diarrhea virus (BVDV) is an important cause of economic losses worldwide. E2 is an immunodominant protein and a promising candidate to develop subunit vaccines. To improve its immunogenicity, a truncated E2 (tE2) was fused to a single chain antibody named APCH, which targets to antigen-presenting cells. APCH-tE2 and tE2 proteins were expressed in the baculovirus system and their immunogenicity was firstly compared in guinea pigs. APCH-tE2 vaccine was the best one to evoke a humoral response, and for this reason, it was selected for a cattle vaccination experiment. All the bovines immunized with 1.5 μg of APCH-tE2 developed high levels of neutralizing antibodies against BVDV up to a year post-immunization, demonstrating its significant potential as a subunit vaccine. This novel vaccine is undergoing scale-up and was transferred to the private sector. Nowadays, it is being evaluated for registration as the first Argentinean subunit vaccine for cattle. Copyright © 2014 Asociación Argentina de Microbiología. Publicado por Elsevier España, S.L.U. All rights reserved.

  1. Desenvolvimento sustentável: uma descrição das principais ferramentas de avaliação Sustainable development: presenting the main measurement methods

    Directory of Open Access Journals (Sweden)

    Hans Michael Van Bellen

    2004-06-01

    Full Text Available Desenvolvimento Sustentável: Uma Descrição das Principais Ferramentas de Avaliação Neste artigo são apresentadas as principais características de três métodos que se propõem a mensurar o grau de sustentabilidade do desenvolvimento. Este métodos foram selecionados por especialistas que atuam em diferentes esferas da sociedade e que lidam com o conceito de desenvolvimento sustentável. Os métodos descritos e analisados são o Ecological Footprint Method, o Dashboard of Sustainability e o Barometer of Sustainability.In this article are presented the main characteristics of three methods which purpose is to measure the rate of sustainability of the development. These methods were selected by specialists who operate at differents levels of the society and also deal with the concept of sustainable development. The methods described and analysed are the Ecological Footprint Method, the Dashboard of Sustainability and the Barometer of Sustainability.

  2. Concurrent development of testicular seminoma and choriocarcinoma of the superior mediastinum, presented as cervical mass: a case report and implications about pathogenesis of germ-cell tumours

    Directory of Open Access Journals (Sweden)

    Bamias Aristotelis

    2006-11-01

    Full Text Available Abstract Background Synchronous presentation of more than one germ cell tumours of different histology in the same patient is considered to be very rare. In these cases of multiple germ cell tumours, strong theoretical and clinical data suggest an underlying common pathogenetic mechanism concerning genetic instability or abnormalities during the pluripotent embryonic differentiation and maturation of the germ cell. Case presentation A 25 year-old young man presented with an enlarging, slightly painful left cervical mass. Despite the initial disorientation of the diagnosis to a possible thyroid disorder, the patient underwent complete surgical resection of the mass revealing mediastinal choriocarcinoma. Subsequent ultrasound of the scrotum indicated the presence of a small lobular node in the upper pole of the left testicle and the patient underwent radical left inguinal orchiectomy disclosing a typical seminoma. Based on these results, the patient received 4 cycles of Bleomycin, Etoposide and Platinum chemotherapy experiencing only mild toxicity and resulting in complete ongoing clinical and biochemical remission. Conclusion The pathogenesis of concurrent germ cell tumours in the same patient remains an area of controversy. Although the genetic instability of the pluripotent germ cell offers an adequate explanation, the possibility of metastasis from the primary, less differentiated tumour to a distant location as a more mature subtype cannot be excluded. Possible development of a metastatic site of different histology and thus biological behaviour (e.g choriocarcinoma should be anticipated. Furthermore, urologists, pathologists and medical oncologists should be meticulous in the original pathological diagnosis in these patients, since there is a significant frequency of germ cell tumours with mixed or overlapping histological elements with diverse potential of evolution and differentiation.

  3. Alarm filtering and presentation

    International Nuclear Information System (INIS)

    Bray, M.A.

    1989-01-01

    This paper discusses alarm filtering and presentation in the control room of nuclear and other process control plants. Alarm generation and presentation is widely recognized as a general process control problem. Alarm systems often fail to provide meaningful alarms to operators. Alarm generation and presentation is an area in which computer aiding is feasible and provides clear benefits. Therefore, researchers have developed several computerized alarm filtering and presentation approaches. This paper discusses problems associated with alarm generation and presentation. Approaches to improving the alarm situation and installation issues of alarm system improvements are discussed. The impact of artificial intelligence (AI) technology on alarm system improvements is assessed. (orig.)

  4. The present, past and future of the study of intellectual disability: challenges in developing countries Pasado, presente y futuro del estudio de la discapacidad intelectual: desafíos en los países en desarrollo

    Directory of Open Access Journals (Sweden)

    Trevor R Parmenter

    2008-01-01

    Full Text Available There is strong evidence that socio-cultural factors largely determine what is seen as competent behaviour. Within western high income countries, driven by the values of utilitarian individualism, the construct of intellectual disability has been largely determined to meet the needs of urban, industrialised societies. In contrast, competence in non-industrialised societies may be more reflected in collaborative, interpersonal problem solving skills such as those found among Nigerian students labelled as intellectually disabled. However, people who are judged to be incompetent or "obtrusive" in countries deficient in support services, are often neglected and consigned to a life in poorly managed segregated institutions, as is the case in China, Russia and some countries in Eastern Europe. Non western countries that have a long history of a globalised economy, such as Taiwan and Japan also remain committed to segregated institutional provisions for people with an intellectual disability, despite a notional acceptance of inclusionary policies enunciated by the United Nations’ Declarations and Conventions. In this paper is concluded that it must be recognised that the population of people with an intellectual disability, regardless of how the condition is defined and classified, is quite heterogeneous. Their needs are also varied and not at all dissimilar to those of the general population. As developing countries adopt western style consumer-driven economies, there is an extreme danger that they, too, will follow the same trajectory of exclusion and impose the culture of "otherness" for a group whose contribution to that society will be devalued. Good science is futile unless it benefits all peoples.Existe amplia evidencia de que los factores socioculturales determinan en gran medida la percepción de conducta competitiva. En los países occidentales de altos ingresos, dominados por los valores del individualismo utilitario, las necesidades de

  5. Effective presentation skills.

    Science.gov (United States)

    Dolan, Robert

    2017-12-29

    Most PhD's will have a presentation component during the interview process, as well as presenting their work at conferences. This article will provide guidance on how to develop relevant content and effectively deliver it to your audience. © FEMS 2017. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  6. Development of an approach for qualitative and quantitative analysis of trace elements present in canine breast tumors by energy dispersive X-ray fluorescence

    Energy Technology Data Exchange (ETDEWEB)

    Cozer, Thamara C.; Conceicao, Andre L.C.; Paschuk, Sergei A.; Rocha, Anna S.S. da; Fagundes, Alana C.F.; Maciel, Karla F.R.; Pimentel, Gustavo R.O.; Badelli, Juliana C., E-mail: thamara.cozer@gmail.com, E-mail: alconceicao@utfpr.edu.br, E-mail: sergei@utfpr.edu.br, E-mail: anna@utfpr.edu.br, E-mail: alanacarolinef@gmail.com, E-mail: karla_rimanski@hotmail.com, E-mail: g_rop@hotmail.com, E-mail: jubadellin@gmail.com [Universidade Tecnologica Federal do Parana (UTFPR), Curitiba, PR (Brazil). Lab. de Espectroscopia de Raio-X

    2015-07-01

    Studies performed with canines indicate that one of the main neoplasia which affect these animals are the breast tumors, representing from 25% to 50% of all kinds of tumors. Moreover, half of them are classified as malignant. In this sense, recent researches on humans have been associated the presence of certain trace elements with the development of breast neoplasia in those individuals. Then, as the breast tissue composition in canines is very similar to the humans, it is expected the same behavior. In this direction, a very effective technique to identify and to determinate trace elements concentration is the EDXRF. However, studies on this area are scarce in the literature. Therefore, in this work it was developed an approach to quantify the main trace elements present into these tumors with high sensitivity. For this purpose, it was determined calibration curves of standards samples diluted in water, with concentrations of Ca, Fe, Cu and Zn, ranging from 400mg/kg to 35mg/kg, from 20mg/kg to 2mg/kg, from 10mg/kg to 1mg/kg and from 100mg/kg to 10mg/kg, respectively. All calibration curves were linearly fitted and on basis in this behavior it was determined the sensitivity of our approach to quantify the concentration of the trace elements mentioned above. In addition, it is important to mention that studies in this area are of great potential, because EDXRF represents a quickly practical and non-destructive alternative to quantify trace elements. (author)

  7. Development of an approach for qualitative and quantitative analysis of trace elements present in canine breast tumors by energy dispersive X-ray fluorescence

    International Nuclear Information System (INIS)

    Cozer, Thamara C.; Conceicao, Andre L.C.; Paschuk, Sergei A.; Rocha, Anna S.S. da; Fagundes, Alana C.F.; Maciel, Karla F.R.; Pimentel, Gustavo R.O.; Badelli, Juliana C.

    2015-01-01

    Studies performed with canines indicate that one of the main neoplasia which affect these animals are the breast tumors, representing from 25% to 50% of all kinds of tumors. Moreover, half of them are classified as malignant. In this sense, recent researches on humans have been associated the presence of certain trace elements with the development of breast neoplasia in those individuals. Then, as the breast tissue composition in canines is very similar to the humans, it is expected the same behavior. In this direction, a very effective technique to identify and to determinate trace elements concentration is the EDXRF. However, studies on this area are scarce in the literature. Therefore, in this work it was developed an approach to quantify the main trace elements present into these tumors with high sensitivity. For this purpose, it was determined calibration curves of standards samples diluted in water, with concentrations of Ca, Fe, Cu and Zn, ranging from 400mg/kg to 35mg/kg, from 20mg/kg to 2mg/kg, from 10mg/kg to 1mg/kg and from 100mg/kg to 10mg/kg, respectively. All calibration curves were linearly fitted and on basis in this behavior it was determined the sensitivity of our approach to quantify the concentration of the trace elements mentioned above. In addition, it is important to mention that studies in this area are of great potential, because EDXRF represents a quickly practical and non-destructive alternative to quantify trace elements. (author)

  8. CONSIDERATIONS FOR THE DEVELOPMENT OF A DEVICE FOR THE DECOMMISSIONING OF THE HORIZONTAL FUEL CHANNELS IN THE CANDU 6 NUCLEAR REACTOR PART 2 - FUEL CHANNEL PRESENTATION

    Directory of Open Access Journals (Sweden)

    Gabi ROSCA FARTAT

    2014-05-01

    Full Text Available As many nuclear power plants are reaching their end of lifecycle, the decommissioning of these installations has become one of the 21st century’s great challenges. Each project may be managed differently, depending on the country, development policies, financial considerations, and the availability of qualified engineers or specialized companies to handle such projects. The principle objective of decommissioning is to place a facility into such a condition that there is no unacceptable risk from the decommissioned facility to public health and safety of the environment. In order to ensure that at the end of its life the risk from a facility is within acceptable bounds, action is normally required. The overall decommissioning strategy is to deliver a timely, costeffective program while maintaining high standards of safety, security and environmental protection. If facilities were not decommissioned, they could degrade and potentially present an environmental radiological hazard in the future. Simply abandoning or leaving a facility after ceasing operations is not considered to be an acceptable alternative to decommissioning.The final aim of decommissioning is to recover the geographic site to its original condition.

  9. Development of multi-walled carbon nanotubes modified pencil graphite electrode for the electrochemical investigation of aceclofenac present in pharmaceutical and biological samples

    Directory of Open Access Journals (Sweden)

    P. Manjunatha

    2018-02-01

    Full Text Available A sensitive and novel chemically modified multi-walled carbon nanotubes modified pencil graphite electrode (MCPGE has been developed for the electrochemical investigation of aceclofenac (ACF. MCPGE was characterized by scanning electron microscopy (SEM, cyclic voltammetry (CV and electrochemical impedance spectroscopy (EIS. Phosphate buffer solution (PBS of pH 7.0 was used as a suitable electrolytic medium, in which aceclofenac (ACF exhibited a sensitive adsorption controlled oxidation peaks at +0.12, +0.32 and +0.51 V and a reduction peak at −0.26 V (vs Ag/AgCl. The experimental conditions were optimised by means of investigating the dependence of peak current on solution pH, concentration and scan rate etc. The electrochemical parameters such as surface concentration (Γ, electron transfer coefficient (α and the standard rate constant (ks were investigated at MCPGE. The oxidative peak currents were varied linearly with concentration in the range between 1 × 10−6 to 60 × 10−6 M with a detection limit of 2.6 × 10−9 M. The UV–Vis absorption spectrum of ACF gave the λmax at 272–273 nm and is attributed to the presence of ACF. The applicability of the MCPGE was illustrated by the determination of ACF present in pharmaceutical and human urine samples.

  10. Whole bladder photodynamic therapy: critical review of present-day technology and rationale for development of intravesical laser catheter and monitoring system.

    Science.gov (United States)

    Nseyo, U O; Lundahl, S L; Merrill, D C

    1990-11-01

    Present-day whole bladder photodynamic therapy (WBPDT) is cumbersome and time consuming because cystoscopic and ultrasonic manipulations are necessary to position the light emitter within the bladder. More important, WBPDT is inherently unsafe and often ineffective since neither uniform photoirradiation nor accurate light dosimetry can be achieved with the techniques employed to photoirradiate the bladder wall. The intravesical laser catheter (IVLC) eliminates the need for cystoscopy and ultrasonography because passage of the treatment fiber into the catheter's central lumen automatically positions its light-diffusing tip within the center of the bladder. Use of the IVLC delivery system also assures accurate photoirradiation of the bladder wall since inflation of the catheter's balloon transforms the asymmetric bladder into a sphere of known diameter. The light sensor incorporated in the balloon wall provides a method to monitor light fluence and measure total light dose. When provided the parameters of bladder volume, laser energy output, and desired light dose, the computerized control system calculates treatment time and automatically adjusts the period of photoirradiation to compensate for variations in laser light production, energy losses during transmission, and for variations in light intensity resulting from the integrating sphere effect of the bladder wall. This delivery system also increases the safety of WBPDT since the monitor automatically discontinues treatment if any unsafe situation, with respect to light fluence, develops during photoirradiation.

  11. Nr 257 - Opinion presented on the behalf of the Commission of sustainable development and land planning on the finance bill for 2013 (nr 235), Volumes 1-10, ecology, sustainable development and planning, regional policies, research and higher education

    International Nuclear Information System (INIS)

    Krabal, Jacques; Sermier, Jean-Marie; Gaillard, Genevieve; Baupin, Denis; Pauvros, Remi; Benisti, Jacques Alain; Fromantin, Jean-Christophe; Calmette, Alain; Plisson, Philippe; Ginesy, Charles-Ange

    2012-01-01

    This huge document comprises ten volumes which present and discuss public programs (objectives, strategies, plans, and actions), public finances, economic activity data and evolutions, debates by commissions, and amendments on different issues. A first set of issues deals with ecology, sustainable development and planning: protection of the environment and risk prevention (volume 1), and then with sustainable development policies (vol. 2), landscapes, water, biodiversity, and geographic and cartographic information (vol. 3), ecological transition (vol. 4), road, railway and water transports (vol. 5), air transports (vol. 6), maritime affairs (vol. 7). The next volume addresses regional policies (vol. 8). The last parts concern research and higher education: research in the field of sustainable development (vol. 9) and in the fields of environments and resources (vol. 10)

  12. Present status of dibaryons

    International Nuclear Information System (INIS)

    Locher, M.P.

    1981-01-01

    In the present notes the author tries to assess the situation regarding dibaryons in the various channels with baryon number two, emphasizing the problems and discussing in greater detail the most recent developments since the Versailles Conference. One of the motivations for the present search of B=2 states is the possibility of colored subclusters for systems with six quarks which cannot occur for ordinary baryons or mesons. (Auth.)

  13. CONSIDERATIONS FOR THE DEVELOPMENT OF A DEVICE FOR THE DECOMMISSIONING OF THE HORIZONTAL FUEL CHANNELS IN THE CANDU 6 NUCLEAR REACTOR. PART 6 - PRESENTATION OF THE DECOMMISSIONING DEVICE

    Directory of Open Access Journals (Sweden)

    Gabi ROSCA FARTAT

    2015-05-01

    Full Text Available The objective of this paper is to present a possible solution for the designing of a device for the decommissioning of the horizontal fuel channels in the CANDU 6 nuclear reactor. The decommissioning activities are dismantling, demolition, controlled removal of equipment, components, conventional or hazardous waste (radioactive, toxic in compliance with the international basic safety standards on radiation protection. One as the most important operation in the final phase of the nuclear reactor dismantling is the decommissioning of fuel channels. For the fuel channels decommissioning should be taken into account the detailed description of the fuel channel and its components, the installation documents history, adequate radiological criteria for decommissioning guidance, safety and environmental impact assessment, including radiological and non-radiological analysis of the risks that can occur for workers, public and environment, the description of the proposed program for decommissioning the fuel channel and its components, the description of the quality assurance program and of the monitoring program, the equipments and methods used to verify the compliance with the decommissioning criteria, the planning of performing the final radiological assessment at the end of the fuel channel decommissioning. These will include also, a description of the proposed radiation protection procedures to be used during decommissioning. The dismantling of the fuel channel is performed by one device which shall provide radiation protection during the stages of decommissioning, ensuring radiation protection of the workers. The device shall be designed according to the radiation protection procedures. The decommissioning device assembly of the fuel channel components is composed of the device itself and moving platform support for coupling of the selected channel to be dismantled. The fuel channel decommissioning device is an autonomous device designed for

  14. The quantifying of road safety developments. Paper presented at the International Conference 'Road Safety in Europe', Birmingham, September 9-11, 1996.

    NARCIS (Netherlands)

    Koornstra, M.J.

    1996-01-01

    The evaluation of the effectiveness of road safety policies and measures must be based on quantative information in road safety developments and the relevant variables that influence that development. However, the concept of road safety itself is not well defined theoretically and quantatively. This

  15. Creation of Audiovisual Presentations as a Tool to Develop Key Competences in Secondary-School Students. A Case Study in Science Class

    Science.gov (United States)

    Ezquerra, Ángel; Manso, Javier; Burgos, Mª Esther; Hallabrin, Carla

    2014-01-01

    New curricular plans based on key competences create the need for new educational proposals that allow their development. This article describes a proposal to develop key competences through project-based learning. The project's objective is the creation of a digital video. The following study was carried out with students in their final two years…

  16. Joint EC-IAEA topical meeting on development of new structural materials for advanced fission and fusion reactor systems. PowerPoint presentations

    International Nuclear Information System (INIS)

    2009-01-01

    The key topics of the meeting are the following: Radiation damage phenomena and modelling of material properties under irradiation; On-going challenges in radiation materials science; Key material parameters and operational conditions of selected reactor designs; Microstructures and mechanical properties of nuclear structural materials; Pathways to development of new structural materials; Qualification of new structural materials; Advanced microstructure probing methods; Special emphasis is given to the application of nuclear techniques in the development and qualification of new structural materials.

  17. Advanced femtosecond lasers enable new developments in non-linear imaging and functional studies in neuroscience, biology and medical applications (Conference Presentation)

    Science.gov (United States)

    Arrigoni, Marco; McCoy, Darryl

    2016-03-01

    In the last few years Multiphoton Excitation Microscopy witnessed a mutation from tool for imaging cellular structures in living animals deeper than other high-resolution techniques, into an instrument for monitoring functionality and even stimulating or inhibiting inter-cellular signalling. This paradigm shift has been enabled primarily by the development of genetically encoded probes like Ca indicators (GECI) and Opsins for optogenetics inhibition and stimulation. These developments will hopefully enable the understanding of how local network of hundreds or thousands of neurons operate in response to actual tasks or induced stimuli. Imaging, monitoring signals and activating neurons, all on a millisecond time scale, requires new laser tools providing a combination of wavelengths, higher powers and operating regimes different from the ones traditionally used for classic multiphoton imaging. The other key development in multiphoton techniques relates to potential diagnostic and clinical applications where non-linear imaging could provide all optical marker-free replacement of H and E techniques and even intra-operative guidance for procedures like cancer surgery. These developments will eventually drive the development of specialized laser sources where compact size, ease of use, beam delivery and cost are primary concerns. In this talk we will discuss recent laser product developments targeting the various applications of multiphoton imaging, as fiber lasers and other new type of lasers gradually gain popularity and their own space, side-by-side or as an alternative to conventional titanium sapphire femtosecond lasers.

  18. The Alignment of Teaching Methodology and Learning Outcomes: The Effect of Students’ Presentations on the Development of English Language Proficiency of Adult Learners

    Directory of Open Access Journals (Sweden)

    Venera Ulker

    2017-12-01

    Full Text Available The aim of this study was to investigate the effectiveness of using students’ presentations on improving English language skills of adult learners and assess its potency to reach the expected learning outcomes. The research was conducted in the Continuing Education Center, Ishik University, Erbil, KRG, Iraq. The target population consisted of 23 English language learners (university graduates, and currently working in the sphere of Education. This study consisted of three major phases: first, explanation, preparation, presentation of the students’ works on the topic of interest and observation of students’ performance, second, teacher-student and student-student discussion of the video-recorded presentations. The last step was the application of the survey, which was designed to measure the participants’ attitude toward the mini-projects they presented in the class. The data were analyzed by means of frequency and percentage, as well as a summarization of the discussions. The main findings show that students’ attitude toward oral presentations, prepared on the topic of their own interest, have a positive attitude on students’ motivation toward learning English and help the adult learners to improve their language in general, and the productive skills in particular.

  19. Summary of the presentations at the international workshop on reducing carbon dioxide emissions from the developing world: Assessment of benefits, costs and barriers

    International Nuclear Information System (INIS)

    Sathaye, J.; Goldman, N.

    1991-06-01

    The ''International Workshop on Reducing Carbon Dioxide Emissions from the Developing World: Assessment of Benefits, Costs and Barriers'' was the second workshop held as part of a project being conducted by the International Energy Studies Group of Lawrence Berkeley Laboratory, in collaboration with experts from leading institutions across the developing world. The goal of the project is to analyze long-range energy consumption in developing countries and its potential contribution to global climate change. The US Environmental Protection Agency (EPA) is supporting this work, the results of which already have made a key contribution to the technical analysis being used as the basis for discussion by the Energy and Industry Sub-group of the Intergovernmental Panel on Climate Change (IPCC). The main purpose of this workshop was two-fold: (1) to discuss the feasibility of implementing the efficiency improvements and fuel switching measures incorporated into the long-term energy scenarios created for 17 developing countries and (2) to examine the costs and benefits of reducing energy-related carbon dioxide emissions generated by developing countries

  20. Opinion presented on behalf of the Economic Affairs Commission on the Finance bill for 2011 (n. 2824), volume 2 Ecology, Sustainable Development and Land Planning, industry and energy

    International Nuclear Information System (INIS)

    2010-01-01

    In her introduction, the author gives a description of the difficult context and situation faced by the industrial sector in France, notably because of the growing activity of emerging countries like China, India or Brazil, but also because of the weakness of research industrial valorization and of the innovation policy (losing the manufacturing capacity leads to losing the capacity for innovation). Then, after a critic of the current policy (reform of the professional tax, a boosting plan with limited results), she comments the contents of public programmes concerning firm and job development, energy, the steering of ecology, energy, sustainable development and sea policies, research in energy and sustainable development and land planning. She comments ways and tools aimed at supporting industrial jobs through innovation: the FSI (strategic investment fund), the competitiveness poles, specific aids to small and medium sized enterprises, tax credit related to research activities. She addresses the energy sector, questioning the French supremacy in the nuclear energy and the increase of electricity price, and criticizing the management of the development of renewable energies (high expenses for no industrial development)

  1. Experimental programme in support of the development of the European ceramic-breeder-inside-tube test-blanket: present status and future work

    International Nuclear Information System (INIS)

    Proust, E.; Roux, N.; Flament, T.; Anzidei, L.; ENEA, Frascati; Casadio, S.; Dell'orco, G.

    1992-01-01

    Four DEMO blanket classes are under investigation within the framework of the European Test-Blanket Development Programme. One of them is featured by the use of lithium ceramic breeder pellets contained inside externally helium cooled tubes. This paper summarizes the main achievements to date of the experimental programme supporting the development of this class of blanket. It also gives an outline of the areas of the breeder material, beryllium, tritium control, and thermomechanical tests, the future work envisaged for the 92-94 period. 53 refs

  2. Annual Proceedings of Selected Research and Development Papers Presented at the National Convention of the Association for Educational Communications and Technology (28th, Orlando, Florida, 2005). Volume 2

    Science.gov (United States)

    Simonson, Michael, Ed.; Crawford, Margaret, Ed.

    2005-01-01

    For the twenty-eighth year, the Research and Theory Division of the Association for Educational Communications and Technology (AECT) is sponsoring the publication of these Proceedings. Papers published in this volume were presented at the National AECT Convention in Orlando, Florida. The Proceedings of AECT's Convention are published in two…

  3. Annual Proceedings of Selected Research and Development Papers Presented at the National Convention of the Association for Educational Communications and Technology (28th, Orlando, Florida, 2005). Volume 1

    Science.gov (United States)

    Simonson, Michael, Ed.; Crawford, Margaret, Ed.

    2005-01-01

    For the twenty-eighth year, the Research and Theory Division of the Association for Educational Communications and Technology (AECT) is sponsoring the publication of these Proceedings. Papers published in this volume were presented at the National AECT Convention in Orlando, Florida. The Proceedings of AECT's Convention are published in two…

  4. Development of a Generalized Version of the Poisson-Nernst-Planck Equations Using the Hybrid Mixture Theory: Presentation of 2D Numerical Examples

    DEFF Research Database (Denmark)

    Johannesson, Björn

    2010-01-01

    A numerical scheme for the transient solution of generalized version of the Poisson-Nernst-Planck equations is presented. The finite element method is used to establish the coupled non-linear matrix system of equations capable of solving the present problem iteratively. The Poisson-Nernst-Planck ......A numerical scheme for the transient solution of generalized version of the Poisson-Nernst-Planck equations is presented. The finite element method is used to establish the coupled non-linear matrix system of equations capable of solving the present problem iteratively. The Poisson......-Nernst-Planck equations represent a set of diffusion equations for charged species, i.e. dissolved ions. These equations are coupled to the ‘internally’ induced electrical field and to the velocity field of the fluid. The Nernst-Planck equations describing the diffusion of the ionic species and the Gauss’ law in used are......, however, coupled in both directions. The governed set of equations is derived from a simplified version of the so-called hybrid mixture theory (HMT). This theory is a special version of the more ‘classical’ continuum mixture theories in the sense that it works with averaged equations at macro...

  5. Studying and developing main nuclear analytical techniques for assessment of the present situation of marine environmental radioactivity in some typical regions of Vietnam

    International Nuclear Information System (INIS)

    Nguyen Trong Ngo; Nguyen Thanh Binh; Phan Son Hai; Mai Thi Huong; Nguyen Thi Linh; Nguyen Van Phuc; Le Nhu Sieu; Nguyen Mong Sinh, Truong Y; Le Ngoc Chung

    2003-01-01

    Typical output of the study is presented, including: 1/ establishing standard procedures for the determination of 238 U and 230 Th radionuclide concentration in marine environmental samples; 2/ acquiring baseline data for the main radionuclide concentration in marine environmental materials (water, sediment and biota) collected from suitable key coastal locations of Vietnam. (NTN)

  6. Development of Metric for Measuring the Impact of RD&D Funding on GTO's Geothermal Exploration Goals (Presentation)

    Energy Technology Data Exchange (ETDEWEB)

    Jenne, S.; Young, K. R.; Thorsteinsson, H.

    2013-04-01

    The Department of Energy's Geothermal Technologies Office (GTO) provides RD&D funding for geothermal exploration technologies with the goal of lowering the risks and costs of geothermal development and exploration. In 2012, NREL was tasked with developing a metric to measure the impacts of this RD&D funding on the cost and time required for exploration activities. The development of this metric included collecting cost and time data for exploration techniques, creating a baseline suite of exploration techniques to which future exploration and cost and time improvements could be compared, and developing an online tool for graphically showing potential project impacts (all available at http://en.openei.org/wiki/Gateway:Geothermal). The conference paper describes the methodology used to define the baseline exploration suite of techniques (baseline), as well as the approach that was used to create the cost and time data set that populates the baseline. The resulting product, an online tool for measuring impact, and the aggregated cost and time data are available on the Open EI website for public access (http://en.openei.org).

  7. Collaboration of patients and health professionals in development and research of care-intervention : Case example presented by a patient research partner

    NARCIS (Netherlands)

    de Boer-Nijhof, N.C.; Maat, B.; de Jong, S.; Kruize, A.A.; Geenen, R.; Ammerlaan, J.W.

    2016-01-01

    Background Patient participation in research and in development of interventions has become a hot topic. Research on health beliefs of stakeholders shows that patients do have other views on health and well-being than health professionals without any experience of a chronic condition themselves

  8. Tracing the development of contemporary park-city relationships : Parc de La Villette and Parc André Citroën (paper + presentation)

    NARCIS (Netherlands)

    Van der Velde, J.R.T.

    2012-01-01

    Since the late post--?war period the relationship between park and city has significantly altered. Parks established between 1980 and 2000 in Paris --? in particular Parc de La Villette and Parc André Citroën – exemplify developments in park design and the park--?city relationship in this period and

  9. Present state-of-the-art and strategy for development of geothermal energy in the world at the end of X X century

    International Nuclear Information System (INIS)

    Andrejevski, Blagoje

    1995-01-01

    A review of the present state-of-the-art for direct application of geothermal energy is given in the paper as follows: 1) For direct application of middle and low-temperature waters for district heating, in agriculture, aquaculture and different industrial processes and balneology; 2) For electricity production. A prognosis for future possible application of geothermal energy in 2020 is given according to two scenarios: i) based on the present compromise ecological politics, with an annual rise of 4% for electricity production and 2-3% for direct application of geothermal energy; and ii) based on the rigid ecological politics, with an annual rise of 6-8% for electricity production and 3% for direct application of geothermal energy. (Original)

  10. Slides for AMI CHEP presentation: Looking back on 10 years of the ATLAS Metadata Interface. Reflections on architecture, code design and development methods.

    CERN Document Server

    Fulachier, J; The ATLAS collaboration; Albrand, S; Lambert, F

    2013-01-01

    . The “ATLAS Metadata Interface” framework (AMI) has been developed in the context of ATLAS, one of the largest scientific collaborations. AMI can be considered to be a mature application, since its basic architecture has been maintained for over 10 years. In this paper we describe briefly the architecture and the main uses of the framework within the experiment (TagCollector for release management and Dataset Discovery). These two applications, which share almost 2000 registered users, are superficially quite different, however much of the code is shared and they have been developed and maintained over a decade almost completely by the same team of 3 people. We discuss how the architectural principles established at the beginning of the project have allowed us to continue both to integrate the new technologies and to respond to the new metadata use cases which inevitably appear over such a time period.

  11. The challenges in diagnosis and gender assignment in disorders of sex development presenting to a pediatric surgical unit in a developing country: the role of laparoscopy and simple tests for gender identity.

    Science.gov (United States)

    Chowdhury, Tanvir K; Kabir, Mahfuzul; Chowdhury, Md Zonaid; Hutson, John M; Banu, Tahmina

    2014-12-01

    We aimed to assess how the diagnosis and determination of gender identity of disorders of sex development (DSD) is different in a developing country from Western medicine, and whether a pediatric surgery department can determine the underlying diagnosis and use simple tools to determine the likely gender identity (GI). We reviewed the records of DSD patients admitted to the Department of Pediatric Surgery, Chittagong Medical College & Hospital (CMCH), Chittagong, Bangladesh, from January 2006 to December 2012 and performed a cross-sectional study on GI and gender-related behavior in these patients during the year 2012. DSD boys and girls answered a GI interview and had their gender role behavior assessed by observations of structural toy play and analyzed for differences in scores. This cohort of DSD patients presented in mid-childhood (6 months-16 years, mean 6.9 years) rather than infancy, and 30% came from consanguineous unions. Congenital adrenal hyperplasia (CAH) constituted only 11 of 50 (22%) of the DSD cohort, and not all families had access to steroid hormone replacement. A simple assessment of GI and gender-related behavior allowed effective gender assignment, as there was significant difference between DSD boys and girls in GI and gender-related behavior score. DSD management in Bangladesh provides some unique challenges because of limited resources. A national reference laboratory for biochemical and genetic testing and development of a quaternary referral center for DSD patients will be helpful. Continued use of the GI interview and gender-related behavior study will enable effective interim decisions about diagnosis and management. Copyright © 2014 Journal of Pediatric Urology Company. Published by Elsevier Ltd. All rights reserved.

  12. Plasma Spheroidised Metals for Additive Manufacturing: Presentation held at 2nd "Advances in Materials Development" Workshop, 24th-25th of April 2017, Prague, Czech Republic

    OpenAIRE

    Kolaric, Ivica

    2017-01-01

    Metal and ceramic powders are the basis for many technical and industrial processes and applications, such as powder metallurgy, thermal spraying, electronics and catalysis. Nevertheless, there is still a need for further developments, because the powdery raw materials eventually determine the properties of final products and may be the cause of the problems in the processing of these: Impurities or corrosion processes at the powder production (e.g. by the grinding processes) can have a disad...

  13. Half of the adults who present to hospital with stroke develop at least one contracture within six months: an observational study.

    Science.gov (United States)

    Kwah, Li Khim; Harvey, Lisa A; Diong, Joanna H L; Herbert, Robert D

    2012-01-01

    What is the incidence of contractures six months after stroke? Can factors measured within four weeks of stroke predict the development of elbow, wrist, and ankle contractures six months later? Prospective cohort study. Consecutive sample of 200 adults with stroke admitted to a Sydney hospital. Loss of range of motion in major joints of the body was measured using a 4-point ordinal contracture scale. In addition, elbow extension, wrist extension, and ankle dorsiflexion range of motion were measured using torque-controlled procedures. Potential predictors of contracture were age, pre-morbid function, severity of stroke, muscle strength, spasticity, motor function, and pain. Measurements were obtained within four weeks of stroke and at six months after stroke. 52% of participants developed at least one contracture. Incidence of contracture varied across joints from 12% to 28%; shoulders and hips were most commonly affected. Muscle strength was a significant predictor of elbow, wrist, and ankle joint range. Prediction models explained only 6% to 20% of variance in elbow, wrist, and ankle joint range. About half of all patients with stroke develop at least one contracture within six months of stroke. Incidence of contractures across all joints ranged from 12% to 28%. Muscle strength is a significant predictor of elbow, wrist, and ankle contractures but cannot be used to accurately predict contractures in these joints. Copyright © 2012 Australian Physiotherapy Association. Published by .. All rights reserved.

  14. Group B Streptococcus vaccine development: present status and future considerations, with emphasis on perspectives for low and middle income countries [version 1; referees: 2 approved

    Directory of Open Access Journals (Sweden)

    Miwako Kobayashi

    2016-09-01

    Full Text Available Globally, group B Streptococcus (GBS remains the leading cause of sepsis and meningitis in young infants, with its greatest burden in the first 90 days of life. Intrapartum antibiotic prophylaxis (IAP for women at risk of transmitting GBS to their newborns has been effective in reducing, but not eliminating, the young infant GBS disease burden in many high income countries. However, identification of women at risk and administration of IAP is very difficult in many low and middle income country (LMIC settings, and is not possible for home deliveries. Immunization of pregnant women with a GBS vaccine represents an alternate pathway to protecting newborns from GBS disease, through the transplacental antibody transfer to the fetus in utero. This approach to prevent GBS disease in young infants is currently under development, and is approaching late stage clinical evaluation. This manuscript includes a review of the natural history of the disease, global disease burden estimates, diagnosis and existing control options in different settings, the biological rationale for a vaccine including previous supportive studies, analysis of current candidates in development, possible correlates of protection and current status of immunogenicity assays. Future potential vaccine development pathways to licensure and use in LMICs, trial design and implementation options are discussed, with the objective to provide a basis for reflection, rather than recommendations.

  15. Tele-facilities for medicine, imaging, quality controls and maintenance services in the health sector for the developing countries and its present and future scope in Bangladesh

    International Nuclear Information System (INIS)

    Jahangir, Saleh Mahmud; Xie, Y.; Uddin, Rokon Md.; Haque, Mohammod Abu Sayid; Hoq, Mahbubul; Mawla, Yasmeen; Morium, Tasnim

    2002-01-01

    The information revolution is transforming health technology itself. With the development of international fiberoptic networks, satellite communications and the ever expanding Internet, technology is now going from revolutionary to routine, from unimaginable to indispensable. There has been little practical experience with telemedicine of a direct clinical kind in the developing world which contains 80% of the world's population. In the 45 poorest countries, it is estimated that only 50% of the population have access to health services. Arguably, it is those same countries that stand to gain most from a simple and cheap telemedicine system, on the principle that it could improve access to health care specialists and enhance research and the education of local health care workers. The work of the Swinfen Charitable trust demonstrates, useful clinical and educational results can be achieved using low cost telemedicine methods. As with the rest of telemedicine, the guiding principle seems to be that it is important to be clear about what problem we are trying to solve. Bangladesh has already entered the age of telemedicine. Under the umbrella of the IAEA TC Project on tele-nuclear medicine and tele-maintenance of nuclear medical equipment it will gradually step forward to reach its desired goal. What role telemedicine will play in the developing countries is yet to be determined. In terms of global health care the relevancy of telemedicine can only be ascertained after successful implementation of these projects

  16. Development of Renal Failure without Proteinuria in a Patient with Monoclonal Gammopathy of Undetermined Significance: An Unusual Presentation of AL Kappa Amyloidosis

    Directory of Open Access Journals (Sweden)

    Yijuan Sun

    2012-01-01

    Full Text Available AL amyloidosis complicating monoclonal gammopathy of undetermined significance (MGUS has usually a predominant glomerular deposition of lambda light chain. Heavy proteinuria is one of its cardinal manifestations. A 78-year-old man with a 9-year history of IgG kappa light-chain-MGUS and normal urine protein excretion developed severe renal failure. Serum levels of kappa light chain and serum IgG had been stable while proteinuria was absent throughout the nine-year period. For the first eight years, he had stable stage III chronic kidney disease attributed to bladder outlet obstruction secondary to prostatic malignancy. In the last year, he developed progressive serum creatinine elevation, without any increase in the serum or urine levels of paraproteins or any sign of malignancy. Renal ultrasound and furosemide renogram showed no evidence of urinary obstruction. Renal biopsy revealed AL amyloidosis, with reactivity exclusive for kappa light chains, affecting predominantly the vessels and the interstitium. Glomerular involvement was minimal. Melphalan and prednisone were initiated. However, renal function continues deteriorating. Deposition of AL kappa amyloidosis developing during the course of MGUS predominantly in the wall of the renal vessels and the renal interstitium, while the involvement of the glomeruli is minimal, leads to progressive renal failure and absence of proteinuria. Renal biopsy is required to detect both the presence and the sites of deposition of renal AL kappa light chain amyloidosis.

  17. Stellar Presentations (Abstract)

    Science.gov (United States)

    Young, D.

    2015-12-01

    (Abstract only) The AAVSO is in the process of expanding its education, outreach and speakers bureau program. powerpoint presentations prepared for specific target audiences such as AAVSO members, educators, students, the general public, and Science Olympiad teams, coaches, event supervisors, and state directors will be available online for members to use. The presentations range from specific and general content relating to stellar evolution and variable stars to specific activities for a workshop environment. A presentation—even with a general topic—that works for high school students will not work for educators, Science Olympiad teams, or the general public. Each audience is unique and requires a different approach. The current environment necessitates presentations that are captivating for a younger generation that is embedded in a highly visual and sound-bite world of social media, twitter and U-Tube, and mobile devices. For educators, presentations and workshops for themselves and their students must support the Next Generation Science Standards (NGSS), the Common Core Content Standards, and the Science Technology, Engineering and Mathematics (STEM) initiative. Current best practices for developing relevant and engaging powerpoint presentations to deliver information to a variety of targeted audiences will be presented along with several examples.

  18. Precision medicine in the age of big data: The present and future role of large-scale unbiased sequencing in drug discovery and development.

    Science.gov (United States)

    Vicini, P; Fields, O; Lai, E; Litwack, E D; Martin, A-M; Morgan, T M; Pacanowski, M A; Papaluca, M; Perez, O D; Ringel, M S; Robson, M; Sakul, H; Vockley, J; Zaks, T; Dolsten, M; Søgaard, M

    2016-02-01

    High throughput molecular and functional profiling of patients is a key driver of precision medicine. DNA and RNA characterization has been enabled at unprecedented cost and scale through rapid, disruptive progress in sequencing technology, but challenges persist in data management and interpretation. We analyze the state-of-the-art of large-scale unbiased sequencing in drug discovery and development, including technology, application, ethical, regulatory, policy and commercial considerations, and discuss issues of LUS implementation in clinical and regulatory practice. © 2015 American Society for Clinical Pharmacology and Therapeutics.

  19. [The specific features of present-day children's physical development in the estimation of the functional sizes of furniture for pupils].

    Science.gov (United States)

    Khramtsov, P I; Strokina, A N; Sotnikova, E N; Butareva, I I; Moldovanov, V V

    2009-01-01

    The authors made mass anthropometric surveys in 923 first-to-fourth-form pupils and determined the values of 5 variables for height groups 2, 3, and 4, used to justify the functional sizes of furniture for pupils: the length of a shoulder slope above the seat, that of an elbow slope above the seat, that of a popliteal space slope above the floor, the distance from the chair hack to the popliteal space, and the highest pelvic width. Differences were found in the anthropometric values in the present-day junior pupils and the equals in age of the early 1970s. The present-day children are characterized by changes in body proportions (a decrease in height and an increase in the length of the shin and femur), which should be kept in mind on optimizing the working place of pupils. It is suggested that popliteal space length rather than the currently applied height should be used as a fitting ratio of anthropometric characteristics to the functional sizes of furniture for pupils.

  20. Optimal MHC-II-restricted tumor antigen presentation to CD4+ T helper cells: the key issue for development of anti-tumor vaccines

    Directory of Open Access Journals (Sweden)

    Accolla Roberto S

    2012-07-01

    Full Text Available Abstract Present immunoprevention and immunotherapeutic approaches against cancer suffer from the limitation of being not “sterilizing” procedures, as very poor protection against the tumor is obtained. Thus newly conceived anti-tumor vaccination strategies are urgently needed. In this review we will focus on ways to provide optimal MHC class II-restricted tumor antigen presentation to CD4+ T helper cells as a crucial parameter to get optimal and protective adaptive immune response against tumor. Through the description of successful preventive or therapeutic experimental approaches to vaccinate the host against the tumor we will show that optimal activation of MHC class II-restricted tumor specific CD4+ T helper cells can be achieved in various ways. Interestingly, the success in tumor eradication and/or growth arrest generated by classical therapies such as radiotherapy and chemotherapy in some instances can be re-interpreted on the basis of an adaptive immune response induced by providing suitable access of tumor-associated antigens to MHC class II molecules. Therefore, focussing on strategies to generate better and suitable MHC class II–restricted activation of tumor specific CD4+ T helper cells may have an important impact on fighting and defeating cancer.

  1. Development of nalidixic acid amphotericin B vancomycin (NAV) medium for the isolation of Campylobacter ureolyticus from the stools of patients presenting with acute gastroenteritis.

    Science.gov (United States)

    O'Doherty, A; Koziel, M; De Barra, L; Corcoran, D; Bullman, S; Lucey, B; Sleator, R D

    2014-01-01

    Recently, Campylobacter ureolyticus has been detected for the first time in the faeces of patients with acute gastroenteritis using polymerase chain reaction (PCR) techniques. Cultural isolation of C. ureolyticusis is not possible using the established selective methods for the isolation of thermophilic Campylobacter spp. from faeces. The aim of the current study is to develop a new selective medium capable of isolating C. ureolyticus from faecal samples. The newly-developed medium consists of Anaerobe Basal Agar with 10 g/L additional agar, 2 g/L sodium formate and 3 g/L sodium fumarate dibasic, to which 10 mg/L nalidixic acid, 10 mg/L amphotericin B and 20 mg/L vancomycin (NAV) are added as selective agents. Validation studies have shown that this experimental selective medium completely inhibits growth of Candida spp. and of Enterococcus spp. and permits reduced growth of selected coliforms and Proteus spp. Growth of Campylobacter ureolyticus on NAV medium is optimal in anaerobic and enriched hydrogen atmospheres. Additionally, an overnight enrichment step using Bolton broth to which 2 g/L sodium formate, 3 g/L sodium fumarate dibasic and the NAV supplement are added, in place of the commercial Bolton broth supplement, allows improved recovery of C. ureolyticus from patients' faeces.

  2. Development of a method to determine the specific environment as a starting point for the strategic analysis and the approach to competitors' Knowledge: presentation and applications

    Directory of Open Access Journals (Sweden)

    Emilio García Vega

    2015-09-01

    Full Text Available The determination of the specific environment is important for the formulation of efficient enterprise strategies, on the basis of a strategic analysis properly focused. This paper suggests a method to help its limitation and identification. With its use, it pretends to offer a simple and practical tool that allows to have a more accurate approach to the identification of the industry that will be analysed, as well as, a clarification of the specification of the direct and substitute competition. Also, with the use of this tool, the managers of a business idea, an experienced or new organization, will have an approximation to the mentioned themes that are of a strategic importance in any management type. Likewise, two applications of the proposed method are presented: the first orientated to a business idea and the second to supermarkets with a high service charge in Lima, Peru.

  3. Technology’s present situation and the development prospects of energy efficiency monitoring as well as performance testing & analysis for process flow compressors

    Science.gov (United States)

    Li, L.; Zhao, Y.; Wang, L.; Yang, Q.; Liu, G.; Tang, B.; Xiao, J.

    2017-08-01

    In this paper, the background of performance testing of in-service process flow compressors set in user field are introduced, the main technique barriers faced in the field test are summarized, and the factors that result in real efficiencies of most process flow compressors being lower than the guaranteed by manufacturer are analysed. The authors investigated the present operational situation of process flow compressors in China and found that low efficiency operation of flow compressors is because the compressed gas is generally forced to flow back into the inlet pipe for adapting to the process parameters variety. For example, the anti-surge valve is always opened for centrifugal compressor. To improve the operation efficiency of process compressors the energy efficiency monitoring technology was overviewed and some suggestions are proposed in the paper, which is the basis of research on energy efficiency evaluation and/or labelling of process compressors.

  4. Anniversary Paper: Development of x-ray computed tomography: The role of Medical Physics and AAPM from the 1970s to present

    Science.gov (United States)

    Pan, Xiaochuan; Siewerdsen, Jeffrey; La Riviere, Patrick J.; Kalender, Willi A.

    2008-01-01

    The AAPM, through its members, meetings, and its flagship journal Medical Physics, has played an important role in the development and growth of x-ray tomography in the last 50 years. From a spate of early articles in the 1970s characterizing the first commercial computed tomography (CT) scanners through the “slice wars” of the 1990s and 2000s, the history of CT and related techniques such as tomosynthesis can readily be traced through the pages of Medical Physics and the annals of the AAPM and RSNA/AAPM Annual Meetings. In this article, the authors intend to give a brief review of the role of Medical Physics and the AAPM in CT and tomosynthesis imaging over the last few decades. PMID:18777932

  5. Present status of the wholesomeness of irradiated foods of basic interest to developing countries, in particular to those in the Asian and Pacific regions

    International Nuclear Information System (INIS)

    Aiyar, A.S.

    1981-01-01

    Among the irradiated foods, the safety of which has already been unconditionally accepted by the Joint Expert Committee on Food Irradiation, are some that, as major items of food, are of considerable interest to the developing countries. There exist, however, technical and economic constraints. The process apparently offers greater promise for certain high-value foods, e.g. frozen sea-foods, spices and tropical fruits for which conventional processing methods fail to yield products that meet hygienic standards, especially of importing nations. The acceptance of such foods from developing countries by the industrialized importing countries could give a boost to food irradiation activities. Most food irradiation applications in practice are likely to be combination processes involving the use of other chemical or physical agents, and the regulatory approach requires rationalization. Wholesomeness of the product subjected to a combination process cannot be inferred merely on the basis of each component of the combination treatment being individually recognized as yielding a wholesome product. Studies on the radiation chemistry of various classes of foods and model systems have served to emphasize their predictive value and have led to the concept of 'chemiclearance' for extrapolating wholesomeness from one food to another in the same general category. It should, however, be emphasized that excessive or undue reliance on the chemical data, coupled with the rigid attitude of some health authorities in respect of the presence of genetic toxicants (zero tolerance), could result in the absurb situation of the chemical approach invalidating the far more relevant animal experimental data on safety

  6. Development and cross-cultural testing of the International Depression Symptom Scale (IDSS): a measurement instrument designed to represent global presentations of depression.

    Science.gov (United States)

    Haroz, E E; Bass, J; Lee, C; Oo, S S; Lin, K; Kohrt, B; Michalopolous, L; Nguyen, A J; Bolton, P

    2017-01-01

    Self-report measurement instruments are commonly used to screen for mental health disorders in Low and Middle-Income Countries (LMIC). The Western origins of most depression instruments may constitute a bias when used globally. Western measures based on the DSM, do not fully capture the expression of depression globally. We developed a self-report scale design to address this limitation, the International Depression Symptom Scale-General version (IDSS-G), based on empirical evidence of the signs and symptoms of depression reported across cultures. This paper describes the rationale and process of its development and the results of an initial test among a non-Western population. We evaluated internal consistency reliability, test-retest reliability and inter-rater reliability of the IDSS-G in a sample N  = 147 male and female attendees of primary health clinics in Yangon, Myanmar. For criterion validity, IDSS-G scores were compared with diagnosis by local psychiatrists using the Structured Clinical Interview for DSM (SCID). Construct validity was evaluated by investigating associations between the IDSS-G and the Patient Health Questionnaire (PHQ), impaired function, and suicidal ideation. The IDSS-G showed high internal consistency reliability ( α  = 0.92), test-retest reliability ( r  = 0.87), and inter-rater reliability ( ICC  = 0.90). Strong correlations between the IDSS-G and PHQ-9, functioning, and suicidal ideation supported construct validity. Criterion validity was supported for use of the IDSS-G to identify people with a SCID diagnosed depressive disorder (major depression/dysthymia). The IDSS-G also demonstrated incremental validity by predicting functional impairment beyond that predicted by the PHQ-9. Results suggest that the IDSS-G accurately assesses depression in this population. Future testing in other populations will follow.

  7. Clinical presentation of women with pelvic source varicose veins in the perineum as a first step in the development of a disease-specific patient assessment tool.

    Science.gov (United States)

    Gibson, Kathleen; Minjarez, Renee; Ferris, Brian; Neradilek, Moni; Wise, Matthew; Stoughton, Julianne; Meissner, Mark

    2017-07-01

    Pelvic venous incompetence can cause symptomatic varicose veins in the perineum, buttock, and thigh. Presentation, symptom severity, and response to treatment of pelvic source varicose veins are not well defined. Currently available tools to measure the severity of lower extremity venous disease and its effects on quality of life may be inadequate to assess disease severity in these patients. The purpose of this study was to evaluate the histories, demographics, and clinical presentations of women with pelvic source varicose veins and to compare these data to a population of women with nonpelvic source varicose veins. A total of 72 female patients with symptomatic pelvic source varicose veins were prospectively followed up. Age, weight, height, parity, and birth weights of offspring were recorded. Both pelvic source varicose veins and saphenous incompetence were identified by duplex ultrasound. Patients were queried as to their primary symptoms, activities that made their symptoms worse, and time when their symptoms were most prominent. Severity of disease was objectively evaluated using the revised Venous Clinical Severity Score (rVCSS) and 10-point numeric pain rating scale (NPRS). Compared with women without a pelvic source of varicose veins (N = 1163), patients with pelvic source varicose veins were younger (mean, 44.6 ± 8.6 vs 52.6 ± 12.9 years; P source varicose veins are a unique subset of patients. They are younger and thinner than those with nonpelvic source varicose veins, have larger infants than the general U.S. population, and have an inverse correlation between age and pain. As the majority of premenopausal patients have increased symptoms during menses, this may be due to hormonal influence. As it is poorly associated with patient-reported discomfort, the rVCSS is a poor tool for evaluating pelvic source varicose veins. A disease-specific tool for the evaluation of pelvic source varicose veins is critically needed, and this study is a first

  8. A monoclonal antibody (SJ-9A4) to P24 present on common alls, neuroblastomas and platelets - I. Characterization and development of a unique radioimmunometric assay.

    Science.gov (United States)

    Komada, Y; Peiper, S C; Melvin, S L; Metzger, D W; Tarnowski, B H; Green, A A

    1983-01-01

    We report the development and characterization of SJ-9A4, a monoclonal antibody (MoAb) produced against common acute lymphoblastic leukemia (C-ALL) cell lines. SJ-9A4 reacted with C-ALL, B-cell chronic lymphocytic leukemia (B-CLL), platelets and C-ALL neuroblastoma (NB) and the K562 cell lines. It had no significant reactivity with erythrocytes, granulocytes, circulating T or B lymphocytes, monocytes, granulocytic cell lines or a Ewing's sarcoma cell line. SJ-9A4 was shown to recognize the same region as two other MoAb to the p24 antigen, BA-2 and DU-ALL-1, as demonstrated by their ability to inhibit the binding of labeled SJ-9A4 to NALM-1 and NB cells. Other MoAb: J5, PI 153/3 and monoclonal anti-HLA-DR antibodies gave no inhibition. A solid phase indirect radioimmunometric assay (IRA) was developed which enabled the detection of P24 from C-ALL cells, utilizing its ability to bind the Ricinus communis agglutinin (RCA1) or wheat germ agglutinin (WGA) and SJ-9A4 simultaneously. When BA-2 and DU-ALL-1 were used in place of SJ-9A4, similar IRA results were obtained. Using the RCA1/SJ-9A4-IRA, P24 from as few as 1.6 X 10(4) cells of a C-ALL cell line could be detected; however, similar extracts of NB cell lines were negative despite high levels of SJ-9A4 binding to intact cells. The presence of P24 in NB extracts was demonstrated by (1) preincubation of NB extracts with SJ-9A4 which blocked MoAb binding to P24 and (2) immunoadsorption of P24 from solubilized membranes of 35S-methionine (met) labeled NB cells. Treatment of NB cells with neuraminidase did not result in IRA binding when either RCA1 or WGA were used as the solid phase lectin indicating that the differences in lectin affinity are not due to over sialation of NB membrane glycoproteins. These findings demonstrate a difference in the glycosylation of P24 from C-ALL and NB cells.

  9. Development and assessment of a website presenting evidence-based information for people with multiple sclerosis: the IN-DEEP project.

    Science.gov (United States)

    Colombo, Cinzia; Filippini, Graziella; Synnot, Anneliese; Hill, Sophie; Guglielmino, Roberta; Traversa, Silvia; Confalonieri, Paolo; Mosconi, Paola; Tramacere, Irene

    2016-03-02

    People with multiple sclerosis (MS) are increasingly using the Internet in the daily management of their condition. They search for high-quality information in plain language, from independent sources, based on reliable and up-to-date evidence. The Integrating and Deriving Evidence, Experiences and Preferences (IN-DEEP) project in Italy and Australia aimed to provide people with MS and family members with an online source of evidence-based information, starting from their information needs. This paper reports on the Italian project's website. Contents, layout and wording were developed with people with MS and pilot-tested. The website was evaluated using an online 29-item questionnaire for ease of language, contents, navigation, and usefulness of information aimed at people with MS, family members and the general population. The website ( http://indeep.istituto-besta.it/) is structured in multiple levels of information. The first topic was interferons-β for people with relapsing-remitting MS. In all, 433 people responded to the survey (276 people with MS, 68 family members and 89 others). The mean age was 45 years, almost 90% had a high school diploma, about 80% had relapsing-remitting MS, and the median disease duration was seven years. About 90% judged the website clear, understandable, useful, and easy to navigate. Ninety percent of people with MS and family members would recommend it to others. Sixty-two percent reported they felt confident in making decisions on interferons-β after reading the website. The model was judged clear and useful. It could be adapted to other topics and diseases. Clinicians may find it useful in their relationship with patients.

  10. Population Dynamics and Educational Development: A Selection of Papers Presented at the Regional Seminar of Experts on Population Dynamics and Educational Planning (Bangkok, Thailand, September 10-18, 1973).

    Science.gov (United States)

    United Nations Educational, Scientific, and Cultural Organization, Bangkok (Thailand). Regional Office for Education in Asia and Oceania.

    A selection of papers on Asian population trends and educational development is presented in four parts. Part I defines the major components of Asian population growth as the rapid decline in mortality after 1945, relative increases in the population of less developed regions, accelerated fertility potential, and unequal distribution of wealth.…

  11. Making your presentation fun: creative presentation techniques

    Energy Technology Data Exchange (ETDEWEB)

    KEENEN,MARTHA JANE

    2000-05-18

    What possesses someone to volunteer and go through hoops and red tape to make a presentation at a conference? For that matter, why does anyone ever present anything to anyone? Actually, presentations are a fact of life and there are many reasons for doing a presentation and doing it well. New and existing staff need training and orientation to the way things are done here. Handing all of them a manual and hoping they read it is pretty much a waste of paper. On the other hand, an effective, entertaining and upbeat presentation on the relevant topics is more likely to stick with those people. They will even have a name and face to remember and seek out when they have an issue on or with that topic. This can be a very effective beginning for networking with new peers. The presenter is seen as knowledgeable, as a source of information on company topics and possibly evaluated as a potential mentor or future manager. Project staff and/or peers benefit from clear, concise, presentations of topical knowledge. This is one way that a group working on various aspects of the same project or program can stay in touch and in step with each other. Most importantly, presentations may be the best or only door into the minds (and budgets) of management and customers. These presentations are a wonderful opportunity to address legal and compliance issues, budget, staffing, and services. Here is a chance, maybe the only one, to demonstrate and explain the wonderfulness of a program and the benefit they get by using the services offered most effectively. An interactive presentation on legal and compliance issues can be an effective tool in helping customers and/or management make good risk management decisions.

  12. Present development of scintillator counters in France

    International Nuclear Information System (INIS)

    Koechlin, Y.; Koch, L.; Lansiart, A.

    1958-01-01

    For a number of years photomultipliers and scintillators have been produced on an industrial scale in France. The AEC has accepted the task of testing their performance, and advising the industry in consequence. This combined effort has resulted in the wide range of photomultipliers and scintillators summarised in the following paper. (author) [fr

  13. The Unilac, development and present status

    International Nuclear Information System (INIS)

    Boehne, D.

    1976-01-01

    During the year 1975 the Unilac heavy ion linear accelerator was completed and stepwise put into operation. The paper summarizes the operating experience obtained so far and compares the performance of the different systems and of characteristic technological details on the basis of the original design concepts. (author)

  14. Present status and future development of WNR

    International Nuclear Information System (INIS)

    Keyworth, G.A.

    1980-01-01

    The Los Alamos Weapons Neutron Research/Proton Storage Ring complex will be a major United States facility for the study of condensed matter science, fundamental interaction physics, and nuclear physics. The experimental facilities, research programs, and a proposed advanced spallation facility are described

  15. Subpart AA Training Presentations

    Science.gov (United States)

    EPA has produced the following training presentation(s) for reporters subject to this subpart. Generally, these presentations explain how to use the reporting system e-GGRT to submit annual GHG reports to EPA.

  16. Subpart FF Training Presentations

    Science.gov (United States)

    EPA has produced the following training presentation(s) for reporters subject to this subpart. Generally, these presentations explain the rule or show how to use the reporting system e-GGRT to submit annual GHG reports to EPA.

  17. Presentation of Pydio

    CERN Multimedia

    CERN. Geneva

    2014-01-01

    **Pydio is an open-source platform for file sharing and synchronisation.** It is wildly used by enterprises and organizations worldwide, including major universities. Pydio comes with a rich web-based interface, native clients for both iOS and Android mobile devices, and lately a new sync client for desktop platforms. Pydio v6 is of great useability and introduces many new features that makes it the ultimate sharing machine. Its architecture makes it a perfect fit for either easily deploying an on-premise dropbox solution, or building more complicated solutions where the box feature is integrated as OEM. Storage-agnostic, Pydio is a simple layer that can be deployed on top of any storage backend, thus providing scalability and high-availability out-of-the-box. Charles du Jeu is the lead developer of the solution and will briefly present its feature and how it can fit for research and engineering purpose. See https://pyd.io/ for more information.

  18. Opinion presented on behalf of the Economical Affairs Commission on the finance bill for 2010 (n. 1946) - Volume II: Sustainable ecology, development and planning. Industry and energy; Avis presente au nom de la Commission des Affaires Economiques sur le projet de loi de finances pour 2010 (n.1946), tome 2 ecologie, developpement et amenagement durables industrie et energie

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2009-10-15

    This report of the French National Assembly first presents the different programmes and actions related to energy and industry for which credits are foreseen in the French finance bill for 2010: development of firms and employment, energy policy, after-mining policy, struggle against climate change, management of ecology, energy, sustainable development, and sea policies, research in the field of energy and sustainable development and planning. The author then outlines the importance of the creation of conditions for a green growth in order to cope with an unprecedented crisis which ruins industrial employment. This implies the support of strategic sectors (energy-efficient building, evolution towards green chemistry, photovoltaic solar energy, renewable heat, innovating vehicles), the implementation of new priorities (smart grids, management of raw materials), and the emergence of ecological technologies promoted by the new tools of a climate policy (carbon tax introduction, improvement of carbon markets). It also implies an industrial output for research by means of a networking of actors (development of competitiveness poles, participation to European partnerships), and a reinforcement of the industrial horizon in the research policy (patenting, start-up development, support to innovating small and middle-sized companies, implementation of a true French capital-risk sector)

  19. ECRIS 2010 - Proceedings and Presentations

    International Nuclear Information System (INIS)

    2012-01-01

    The workshop focussed on the latest developments in performance, modeling and applications of ECR ion sources along with the associated physics and technologies, including plasma physics, beam optics, beam diagnostics, magnet technology.... The presentations were organized around 8 topics: 1) status of ECRIS operation, 2) new developments, 3) ion beams and low energy beam transport (LEBT), 4) pulsed operation, 5) applications, and 6) plasma and beam investigations. Most papers are accompanied with the slides of their presentation

  20. Presentation on systems cluster research

    Science.gov (United States)

    Morgenthaler, George W.

    1989-01-01

    This viewgraph presentation presents an overview of systems cluster research performed by the Center for Space Construction. The goals of the research are to develop concepts, insights, and models for space construction and to develop systems engineering/analysis curricula for training future aerospace engineers. The following topics are covered: CSC systems analysis/systems engineering (SIMCON) model, CSC systems cluster schedule, system life-cycle, model optimization techniques, publications, cooperative efforts, and sponsored research.

  1. The Art of Presenting.

    Science.gov (United States)

    Lukey-Coutsocostas, Kathryn; Tanner-Bogia, Julia

    1998-01-01

    Provides suggestions for helping nonnative English speakers in planning and delivering an effective presentation. Topics covered include the following: fears, choosing a topic, planning, title/summary/abstract, equipment, delivery, and evaluation of the present. (Author/VWL)

  2. Workshop Presentations: Overviews

    Data.gov (United States)

    National Aeronautics and Space Administration — These slides were presented at the AePW, April 21-22, 2012. Additional presentations can be found on each of the associated analysis webpages. Separate pages contain...

  3. Thymoma presenting with infarction.

    Science.gov (United States)

    Gray, Katherine M; Windsor, Morgan

    2004-06-01

    Thymomas are the most common tumours of the anterior mediastinum with most patients presenting incidentally. We present a case of thymoma presenting with sudden onset severe chest pain and raised plasma aminotransaminases secondarily to spontaneous infarction. We discuss the presence of these aminotransaminases in this highly unusual presentation of thymoma and believe our case demonstrates the inherent limitations of plasma enzymes due to their lack of specificity and sensitivity.

  4. Presenting Food Science Effectively

    Science.gov (United States)

    Winter, Carl K.

    2016-01-01

    While the need to present food science information effectively is viewed as a critical competency for food scientists by the Institute of Food Technologists, most food scientists may not receive adequate training in this area. Effective presentations combine both scientific content and delivery mechanisms that demonstrate presenter enthusiasm for…

  5. Rotating Poster Presentations

    Science.gov (United States)

    Lagares, Manuel; Reisenleutner, Sandra

    2017-01-01

    Oral presentations are a common practice in foreign language classes, often used to assess students' speaking skills. Usually, the presentations are delivered by students in front of the class, often with PowerPoint slides or Prezi as support. However, frequently the audience does not engage with the presentation and thus, the benefits of this…

  6. Innovative presentations for dummies

    CERN Document Server

    Anthony, Ray

    2014-01-01

    Be the speaker they follow with breakthrough innovative presentations Innovative Presentations For Dummies is a practical guide to engaging your audience with superior, creative, and ultra-compelling presentations. Using clear language and a concise style, this book goes way beyond PowerPoint to enable you to reimagine, reinvent, and remake your presentations. Learn how to stimulate, capture, and hold your audience in the palm of your hand with sound, sight, and touch, and get up to speed on the latest presentation design methods that make you a speaker who gets audiences committed and acting

  7. Crystallography: past and present

    Science.gov (United States)

    Hodeau, J.-L.; Guinebretiere, R.

    2007-12-01

    structure (chemical order, anisotropy, charge transfer, magnetic order) versus an external parameter like temperature, pressure, magnetic or electric field. Modern crystallography is also extended to the study of very small crystals, powders, ill-ordered or non-crystallized materials. Thus presently, crystallography is concerned with any solid that “scatters” an incident beam. Nevertheless, as quoted by A. Guinier, “the problems facing crystallographers have only changed, ... new ones have appeared which require reflection and imagination, ... and which in turn may still bring much joy to all those who like crystallography” [4]. Such developments open up crystallography to modern materials like artificial ones and nanostructures with low- and/or multi-scaled-periodicities and/or extremely small “crystal size” and to materials of the “real world”, with mixtures of phases and/or amorphous contribution and/or defects, a common characteristic of ancient materials analysed in patrimonial research. In our contribution we will show by selected examples that these improvements were allowed (i) by the use of powerful sources, apparatus and detectors which allow micro-diffraction, in-situ diffraction, spectroscopy, resonant scattering, inelastic scattering, coherent scattering, (ii) by the development of methods like diffraction anomalous fine structure (DAFS), pair distribution function (PDF), simulated annealing, single object reconstruction, (iii) by combination of scattering and spectroscopy and by combination of scattering and microscopy. Such combination of different approaches is very efficient and, as said by H. Curien at the IUCr Bordeaux Congress in 1990, “in crystallography, there is a constant alternation between the crystal space and its associated reciprocal space, ... the alternation between experiment and model building is another feature of crystallography activity ..., the crystallographer relies both on his computer and on his diffractometer

  8. Water plants past and present

    DEFF Research Database (Denmark)

    Riis, Tenna

    2006-01-01

    How has the condition of the environment developed during the last 100 years? This is an important question because the conditions of the past infl uence those of the present, and knowledge about this development makes it possible to evaluate the causes of changes in species richness, species com...

  9. Conns' syndrome - atypical presentations

    International Nuclear Information System (INIS)

    Kumar, K V S Hari; Modi, K D; Jha, Sangeeta; Jha, Ratan

    2009-01-01

    Primary hyperaldosteronism (Conns' syndrome) commonly presents with a combination of clinical features of hypokalemia and hypertension. Atypical presentations like normotension, normokalemia and neurological ailments are described in few cases. We encountered two such cases, the first presenting with acute neurological complaint and second case having insignificant hypertension. Both the patients had a characteristic biochemical and imaging profile consistent with primary hyperaldosteronism and responded to surgical resection of adrenal adenoma. (author)

  10. Behavioural present value

    OpenAIRE

    Krzysztof Piasecki

    2013-01-01

    Impact of chosen behavioural factors on imprecision of present value is discussed here. The formal model of behavioural present value is offered as a result of this discussion. Behavioural present value is described here by fuzzy set. These considerations were illustrated by means of extensive numerical case study. Finally there are shown that in proposed model the return rate is given, as a fuzzy probabilistic set.

  11. CERN Electronics Pool presentations

    CERN Multimedia

    2011-01-01

    The CERN Electronics Pool has organised a series of presentations in collaboration with oscilloscope manufacturers. The last one will take place according to the schedule below.   Time will be available at the end of the presentation to discuss your personal needs. The Agilent presentation had to be postponed and will be organised later. -     Lecroy: Thursday, 24 November 2011, in 530-R-030, 14:00 to 16:30.

  12. Energetic infrastructure and sustainable development: present situation and alternatives for the state of Roraima, Brazil; Infraestrutura energetica e desenvolvimento sustentavel: situacao atual e alternativas para o estado de Roraima, Brasil

    Energy Technology Data Exchange (ETDEWEB)

    Marques, Antonio de Oliveira

    2009-07-01

    This study aims to analyze the current situation of energy structure available of Roraima state, as well as viable alternatives to enlarge the base of the structure and minimize the impact to the environment, thus providing the support necessary for sustainable development of the state. In the theoretical framework, sought to present the main links between natural resources, economy and environment, and between infrastructure and economic development, where it is present energy infrastructure. Examined the capacity of generating electricity in Roraima and the existent limitations of the current structure available. Verifying the available options for energy production from renewable source in the state, analyzing their potential and viability. Were also proposed for energy planning strategies with the goal of providing the essential foundation for the sustainable development of Roraima. As a result of the search is highlighted the source of energy with the greatest potential in the state is water. The biomass and solar energy can be alternatives to attend isolated communities. The study also found that the current structure of energy Roraima does not provide the support necessary for a reliable and sustainable development. (author)

  13. Opinion presented on the behalf of the Commission for Economic Affairs on the finance bill project for 2015 (nr 2234) - Volume III - ecology, sustainable development and mobility - energy. Nr 2262

    International Nuclear Information System (INIS)

    Battistel, Marie-Noelle

    2014-01-01

    After a presentation of budgetary allocations for energy, this report discusses the participation of agriculture to energy transition, particularly with the emergence of farmers who are also energy producers (development of photovoltaic on agricultural hangars, development of anaerobic digestion supported by public policies), and the development of a French model of anaerobic digestion oriented towards circular economy (reasons for supporting anaerobic digestion, solutions to boost the sector). The last part addresses the management of consumption by farmers and how to take a new energy problematic into account: as agriculture is a sector highly dependent on energy and with a high consumption of fossil energies, efforts are made to reduce this consumption and improve energy efficiency by means of the energy performance plan

  14. Conjugando el presente

    Directory of Open Access Journals (Sweden)

    Héctor Rojas Herazo

    1968-06-01

    Full Text Available La añoranza suele ser, casi siempre, la línea critica de menor resistencia. El lema de que "todo tiempo pasado fue mejor" tiene un poco la culpa. En cualquier orden del conocimiento el pasado sigue el verdadero presente. Ese presente en que nos gusta respirar y vivir. Nada de compromiso circundante. Nada de inmediatez.

  15. Development

    DEFF Research Database (Denmark)

    Alavi, Amin

    2012-01-01

    reviewing WTO rules addressing development and developing countries and the EU´s application of them......reviewing WTO rules addressing development and developing countries and the EU´s application of them...

  16. Workshop Presentations: HIRENASD Analysts

    Data.gov (United States)

    National Aeronautics and Space Administration — These slides were presented at the AePW, April 21-22, 2012. They detail the analytical results generated by each of the participating analysis teams for the HIRENASD.

  17. Workshop Presentations: RSW Analysts

    Data.gov (United States)

    National Aeronautics and Space Administration — These slides were presented at the AePW, April 21-22, 2012. They detail the analytical results generated by each of the participating analysis teams for the...

  18. Atypical Presentation of Neurosyphilis

    Directory of Open Access Journals (Sweden)

    L C Anand

    1980-01-01

    Full Text Available Five cases of neurospyhilis with atypical manifestation have been reported. Of these four cases presented as acute neurological illness and showed variable recovery after antisyp′iiilitic therapy. One of these cases had parinaud sip which was unaffected by treatment One case presented as dementia and gave poor response to therapy. In only one of these five cases was reagin in CSF demonstrated. Lange′s colloidal gold test was negative in all. As such failure to demonstrate reagin in CSF does not rule out the diagnosis of neurosyphilis. In an antibiotic era patients may inadvertently receive some antibiotics prior to presentation to a clinician and therefore are unlikely to present with typical neurological and laboratory findings.

  19. Fostering oral presentation performance

    NARCIS (Netherlands)

    Ginkel, van Stan; Gulikers, Judith; Biemans, Harm; Mulder, Martin

    2017-01-01

    Previous research revealed significant differences in the effectiveness of various feedback sources for encouraging students’ oral presentation performance. While former studies emphasised the superiority of teacher feedback, it remains unclear whether the quality of feedback actually differs

  20. PRESENT STATUS IN INDIA

    Indian Academy of Sciences (India)

    First page Back Continue Last page Overview Graphics. PRESENT STATUS IN INDIA. FIXED LINES – 36 MILLION. MOBILE CONNECTIONS – 14 MILLION. TELEDENSITY APPROXIMATELY 5. INTERNET CONNECTIONS – 5 MILLION. INTERNET USERS NEARLY – 25 MILLION.

  1. Communication and presentation skills

    OpenAIRE

    Lorencová, Ivana

    2014-01-01

    This bachelor thesis deals with individual factors of communication and basic presentations skills. The theoretical part specifies the basic elements of verbal and non-verbal communication and basic factors connected with preparation and realisation of a presentation. The practical part of the thesis comprises an analysis of impacts of speaker's visual and other communication influences over an audience. The results are applied to a Multimedia Display exhibition taking place during the bachel...

  2. Tritium monitoring : present status

    International Nuclear Information System (INIS)

    Rathnakaran, M.; Singh, A.N.

    1993-01-01

    The report summarizes the present status of techniques employed for the monitoring of tritium in water, air and other samples. A brief mention of the work done by numerous workers in the field, critical comments about the work and a fairly exhaustive list of references about the work done during the last 4 decades has been presented. On-line monitoring on real time basis in nuclear reactors is also discussed. (author). 83 refs., 10 refs., 2 tabs

  3. Neurofibromatosis of atypical presentation.

    Science.gov (United States)

    Tato, B P; Sáez, A C; Recuero, J L D; Dorado, M M; Fernández, P R; de Paz, F S

    2005-09-01

    Neurofibromatosis (NF) is considered to be a heterogeneous neuroectodermal disease clinically defined by the presence of neurofibromas, multiple café-au-lait spots, intertriginous freckles and Lisch nodules. Mosaicism explains atypical presentations of the disease. Early mutations, before tissue differentiation, give rise to generalized disease. We report an atypical presentation of neurofibromatosis with an unusual distribution of neurofibromas, a peculiar, clinically and pathologically, neurofibroma on the trunk and the association with an ovarian serous cystoadenofibroma.

  4. Sheehan's syndrome presenting as psychosis: a rare clinical presentation

    Science.gov (United States)

    Dar, Mohamand Maqbool; Arif, Tasleem; Bashir, Haamid; Bhat, Mohammad Hayat; Ahmed, Javid

    2013-01-01

    Sheehan's syndrome (SS) refers to the occurrence of varying degree of hypopituitarism after parturition (1). It is a rare cause of hypopituitarism in developed countries owing to advances in obstetric care and its frequency is decreasing worldwide. However, it is still frequent in underdeveloped and developing countries. Sheehan's syndrome is often diagnosed late as it evolves slowly (2,3). Reports of psychoses in patients with Sheehan's syndrome are rare. Herein, a case report of psychosis in a 31 year old woman who developed Sheehan's syndrome preceded by postpartum haemorrhage is presented. Treatment with thyroxine and glucocorticoids resulted in complete remission after attaining euthyroid and eucortisolemic state. PMID:23483784

  5. Statistical data presentation.

    Science.gov (United States)

    In, Junyong; Lee, Sangseok

    2017-06-01

    Data are usually collected in a raw format and thus the inherent information is difficult to understand. Therefore, raw data need to be summarized, processed, and analyzed. However, no matter how well manipulated, the information derived from the raw data should be presented in an effective format, otherwise, it would be a great loss for both authors and readers. In this article, the techniques of data and information presentation in textual, tabular, and graphical forms are introduced. Text is the principal method for explaining findings, outlining trends, and providing contextual information. A table is best suited for representing individual information and represents both quantitative and qualitative information. A graph is a very effective visual tool as it displays data at a glance, facilitates comparison, and can reveal trends and relationships within the data such as changes over time, frequency distribution, and correlation or relative share of a whole. Text, tables, and graphs for data and information presentation are very powerful communication tools. They can make an article easy to understand, attract and sustain the interest of readers, and efficiently present large amounts of complex information. Moreover, as journal editors and reviewers glance at these presentations before reading the whole article, their importance cannot be ignored.

  6. Book Presentation | 27 February

    CERN Multimedia

    The CERN Library

    2013-01-01

    "A caccia del bosone di Higgs. Magneti, governi, scienziati e particelle nell'impresa scientifica del secolo" by Luciano Maiani and Romeo Bassoli, published by Mondadori. On Wednesday 27 February Luciano Maiani will present the book "A caccia del bosone di Higgs. Magneti, governi, scienziati e particelle nell'impresa scientifica del secolo". More information here. The presentation will take place in the Council Chamber at 16.00 and will be followed by a debate and book signing. The book will be on sale. You are cordially invited.

  7. Milk: Past and Present

    Science.gov (United States)

    Bulajić, S.; Đorđević, J.; Ledina, T.; Šarčević, D.; Baltić, M. Ž.

    2017-09-01

    Although milk/dairy consumption is part of many cultures and is recommended in most dietary guidelines around the world, its contribution to overall diet quality remains a matter of controversy, leading to a highly polarized debate within the scientific community, media and public sector. The present article, at first, describes the evolutionary roots of milk consumption, then reviews the milk-derived bioactive peptides as health-promoting components. The third part of the article, in general, presents the associations between milk nutrients, disease prevention, and health promotion.

  8. COI Structural Analysis Presentation

    Science.gov (United States)

    Cline, Todd; Stahl, H. Philip (Technical Monitor)

    2001-01-01

    This report discusses the structural analysis of the Next Generation Space Telescope Mirror System Demonstrator (NMSD) developed by Composite Optics Incorporated (COI) in support of the Next Generation Space Telescope (NGST) project. The mirror was submitted to Marshall Space Flight Center (MSFC) for cryogenic testing and evaluation. Once at MSFC, the mirror was lowered to approximately 40 K and the optical surface distortions were measured. Alongside this experiment, an analytical model was developed and used to compare to the test results. A NASTRAN finite element model was provided by COI and a thermal model was developed from it. Using the thermal model, steady state nodal temperatures were calculated based on the predicted environment of the large cryogenic test chamber at MSFC. This temperature distribution was applied in the structural analysis to solve for the deflections of the optical surface. Finally, these deflections were submitted for optical analysis and comparison to the interferometer test data.

  9. Presentism and black holes

    NARCIS (Netherlands)

    Sengers, G. (Geurt)

    2017-01-01

    textabstractIn a recent publication in the European Journal for Philosophy of Science (Romero and Pérez, European Journal for Philosophy of Science, 4, 293–308, 2014), Romero and Pérez claim to reveal new trouble for the already difficult life of presentism in relativistic spacetimes. Their argument

  10. PowerPoint Presentation

    Indian Academy of Sciences (India)

    Table of contents. PowerPoint Presentation · CHANDIPURA VIRUS · Slide 3 · Slide 4 · Slide 5 · VIRUSES · PROPERTIES OF VIRUSES · CLASSIFICATION OF VIRUSES · VIRUS FAMILIES · VIRUS FAMILIES – contd · General Classification · Slide 12 · Slide 13 · Slide 14 · Slide 15 · Slide 16 · Slide 17 · Slide 18 · Slide 19.

  11. Presentation of CEA

    International Nuclear Information System (INIS)

    Graf, J.J.

    1976-01-01

    The organization of the CEA, its missions and means are presented. Its activities in the field of light water reactors, fast neutron reactors and PWR reactors of small and medium power for electricity and/or heat generation are emphasized [fr

  12. Present State Examination

    DEFF Research Database (Denmark)

    Pedersen, Kamilla; Bertelsen, Aksel

    Present State Examination (PSE) 5. udgave er en revideret version af speciallæge i psykiatri Aksel Bertelsens oprindelige materiale. Aksel Bertelsen er ophavsmand til PSE og til den danske udgave af ICD-10. Revisionen omfatter et forbedret layout, en modernisering af sproget, tilføjelse af...

  13. PowerPoint Presentation

    Indian Academy of Sciences (India)

    Table of contents. PowerPoint Presentation · Slide 2 · Receptor-mediated endocytosis · Slide 4 · Publications – Direct therapeutic approaches · Importance of ECM recognition · Publications – ECM interactions · Slide 8 · L. donovani, when attached to the macrophage surface, behaves like any other microbe which are killed ...

  14. Econophysics: Past and present

    Science.gov (United States)

    de Area Leão Pereira, Eder Johnson; da Silva, Marcus Fernandes; Pereira, H. B. B.

    2017-05-01

    This paper provides a brief historical review of the relationship between economics and physics, beginning with Adam Smith being influenced by Isaac Newton's ideas up to the present day including the new econophysics discipline and some of the tools applied to the economy. Thus, this work is expected to motivate new researchers who are interested in this new discipline.

  15. Interactive Presentation of Content

    Science.gov (United States)

    Magdin, Martin; Turcáni, Milan; Vrábel, Marek

    2009-01-01

    In the paper we discus about design of universal environment for solution of creating effective multimedia applications with accent on the implementation of interactive elements with the possibility of using the adaptive systems (AS). We also discuss about possibilities of offline presentation of this interactive multimedia adaptive animations…

  16. Unusual presentation of thyrotoxicosis

    African Journals Online (AJOL)

    Thus besides the induction of movement disorders by hyperthyroidism, a previously unrecognized pathogenetic role for antiphospholipid antibodies is a possibility in at least some patients with hyperthyroidism related choreal". It has been postulated that young women who present with Graves' disease should be tested for ...

  17. Agriculture Oral Presentations

    International Nuclear Information System (INIS)

    1997-01-01

    This publication contains 23 papers related to the use of nuclear techniques in plant breeding in Turkey, effect of gamma irradiations on growing various plants, mutations and soil chemistry, etc., presented at 4. International Congress of Nuclear Agriculture and Animal Science in Bursa, Turkey, 25-27 Sep 1996. A separate abstract was prepared for each paper

  18. Presentation of 2004 earnings

    International Nuclear Information System (INIS)

    2005-03-01

    This presentation offers financial information on the AREVA Group earnings for the year 2004. With manufacturing facilities in over 40 countries and a sales network in over 100, Areva offers customers technological solutions for nuclear power generation and electricity transmission and distribution. The Group also provides interconnect systems to the telecommunications, computer and automotive markets. (A.L.B.)

  19. The presentation and treatment

    African Journals Online (AJOL)

    user

    entries representing this item type. In printed dictionaries this inferior way of presentation is partially due to a lack of space but also to an insufficient focus on collocations as fully-fledged items in dictionary articles. This insufficient focus also prevails in many online dictionaries. Collocations are significant units in the syntactic ...

  20. Imagined futures, present lives

    DEFF Research Database (Denmark)

    Dalsgaard, Anne Line; Wildermuth, Norbert

    2006-01-01

    is discussed centrally in this attempt to contribute to an empirically grounded understanding of the role that media play for youth in their striving to ‘find a place in life'. In the empirical context presented in the article, imaginations, expanded and circulated by a globalized media circuit...

  1. AECL present and future

    International Nuclear Information System (INIS)

    Foster, J.S.

    The history and present activities of the Crown corporation AECL are described. AECL owns limited interests in nuclear power plants and a Manitoba transmission system. AECL is the world's foremost producer of heavy water, and exports CANDU type reactors and radiation processing equipment. AECL backs up the Canadian nuclear power program wherever there is no conflict with private enterprise. (E.C.B.)

  2. An unusual presentation of sporotrichosis

    Directory of Open Access Journals (Sweden)

    S S Vaishampayan

    2013-01-01

    Full Text Available Sporotrichosis can mimic a few diseases. Sporotrichosis presenting as a hypoaesthetic plaque or plaque suggestive of leprosy has not been mentioned in literature. Herein we present a case of a 26 years old man who presented with hypoesthetic plaque on left ankle and was clinically diagnosed to have borderline tuberculoid leprosy who later developed few nodules in linear fashion on left leg, which ruptured to form non healing ulcers. Culture from ulcer grew Sporothrix schenckii. Patient was successfully treated with oral potassium iodide.

  3. Country Presentation Malawi

    International Nuclear Information System (INIS)

    Kamperewera, A.M; Chiumbuzo, T.M.; Bonongwe, A.

    2010-01-01

    Discusses incidents and developments in illicit trafficking, unauthorized activities involving nuclear materials in Malawi, government systems for prevention and detection of nuclear material trafficking and response to unauthorized activities involving nuclear materials and systems put in place for nuclear trafficking information management and coordination.

  4. The Past and Present

    Science.gov (United States)

    Archer, Mary D.

    2015-10-01

    The following sections are included: * Introduction * Milestones in the development of photovoltaic technology * The crystalline silicon solar cell * GaAs and III-V multijunction cells * Concentrator photovoltaics * Inorganic thin-film cells * Organic and hybrid technologies * Overview of photovoltaic cell operation * Other junction types * Structure of this book * References

  5. Organising and presenting information.

    Science.gov (United States)

    Kankanady, Raghavendra; Wells, Marilyn

    2013-01-01

    Information management can be a daunting process for clinicians, health care providers and policy makers within the health care industry. This chapter discusses the importance of information classification and information architecture in the information economy and specific challenges faced within the health care industry. The healthcare sector has industry specific requirements for information management, standards and specifications for information presentation. Classification of information based on information criticality and the value in the health care industry is discussed in this paper. Presentation of information with reference to eHealth standards and specifications for healthcare information systems and their key requirements are also discussed, as are information architecture for eHealth implementation in Australia. This chapter also touches on information management and clinical governance since the importance of information governance is discussed by various researchers and how this is becoming of value to healthcare information management.

  6. PowerPoint Presentation

    Indian Academy of Sciences (India)

    PowerPoint Presentation · Slide 2 · Slide 3 · Slide 4 · Slide 5 · Slide 6 · HABITAT TYPES & PRIMATE GROUPS · Slide 8 · Slide 9 · TOPOGRAPHY OF KARNATAKA · SOUTHERN PLATEAU · Slide 13 · Slide 14 · WESTERN GHATS · Slide 16 · Slide 17 · LARGE SQUIRRELS · Slide 19 · OPEN PLAINS · Slide 21 · Slide 22.

  7. PowerPoint Presentation

    Indian Academy of Sciences (India)

    PowerPoint Presentation · Slide 2 · Slide 3 · Getting Smart with Smart Windows! Slide 5 · Energy Crisis!! Total World Primary Energy Supply · “We Ride on Water!” Volume for storage of 4 kg H2 in different states · Slide 10 · Linkers make a Difference! Coordination Polymers · Principle Behind Formation of MOFs · Slide 14.

  8. PowerPoint Presentation

    Indian Academy of Sciences (India)

    Table of contents. PowerPoint Presentation · Slide 2 · Distribution of viral encephalitis · Slide 4 · Slide 5 · Slide 6 · Slide 7 · Slide 8 · Slide 9 · Slide 10 · Slide 11 · Slide 12 · Slide 13 · Slide 14 · Slide 15 · Slide 16 · Slide 17 · Slide 18 · Slide 19 · Slide 20 · Slide 21 · Slide 22 · Slide 23 · Status dystonicus in Japanese encephalitis.

  9. PowerPoint Presentation

    Indian Academy of Sciences (India)

    Table of contents. PowerPoint Presentation · Slide 2 · Slide 3 · Slide 4 · Slide 5 · Slide 6 · Slide 7 · Slide 8 · Slide 9 · Slide 10 · Slide 11 · Slide 12 · Slide 13 · Slide 14 · Slide 15 · Slide 16 · Slide 17 · Slide 18 · Slide 19 · Slide 20 · Slide 21 · Slide 22 · Slide 23 · Slide 24 · Slide 25.

  10. PowerPoint Presentation

    Indian Academy of Sciences (India)

    PowerPoint Presentation · Slide 2 · Slide 3 · Slide 4 · Slide 5 · Slide 6 · Slide 7 · Planck CMB sky map · Slide 9 · Planck Angular power spectrum · CMB Polarization spectra · Slide 12 · Slide 13 · Cosmological Parameters · Slide 15 · Slide 16 · Slide 17 · Slide 18 · Slide 19 · Hemispherical asymmetry · Modulation model of SI ...

  11. PowerPoint Presentation

    Indian Academy of Sciences (India)

    PowerPoint Presentation · Slide 2 · The Heat Engine of the Earth · Slide 4 · Volcanoes at various settings · Slide 6 · Why study carbonatites? Uniqueness of Carbonatites · Origin of Carbonatites · Slide 10 · Slide 11 · Slide 12 · Slide 13 · Primary Objectives · Methods/Tracers Used · Slide 16 · Slide 17 · Slide 18 · Slide 19.

  12. PowerPoint Presentation

    Indian Academy of Sciences (India)

    PowerPoint Presentation · Slide 2 · Slide 3 · Demands for Space Transportation Systems for the next 30 years · Slide 5 · Slide 6 · Launch demand & costs · Slide 8 · Slide 9 · Slide 10 · Slide 11 · Slide 12 · Slide 13 · Slide 14 · Slide 15 · Slide 16 · Slide 17 · Slide 18 · Slide 19 · Slide 20 · Slide 21 · Slide 22 · Slide 23 · Slide 24.

  13. Presentation = Speech + Slides

    Directory of Open Access Journals (Sweden)

    Derik Badman

    2008-12-01

    Full Text Available Back in October, Aaron Schmidt posted “HOWTO give a good presentation” to his blog walking paper. His second bullet point of “thoughts” on good presentations is: Please don’t fill your slides with words. Find some relevant and pretty pictures to support what you’re saying. You can use the pictures to remind yourself what you’re going [...

  14. Cryptococcal meningitis presenting as uveitis.

    OpenAIRE

    Stone, S P; Bendig, J; Hakim, J; Kinnear, P E; Azadian, B S; Clifford-Rose, F

    1988-01-01

    A patient presented with a posterior uveitis. An inferior plaque of retinal exudation was seen. Full investigation failed to establish a cause until six weeks later, when cryptococcal meningitis developed. The patient was immunocompetent. Exudation in relation to retinal vessels is unusual in idiopathic posterior uveitis, and cryptococcosis should be considered in the differential. Diagnosis is by lumbar puncture or vitreous aspiration.

  15. Rose breeding: past, present, prospects

    NARCIS (Netherlands)

    Vries, de D.P.; Dubois, L.A.M.

    1996-01-01

    In this review the PAST, PRESENT and PROSPECT will be considered as three separate periods in the history of the breeding and development of rose cultivars. The recurring theme is the genetic variation. This theme was chosen because there is justified doubt as to sufficient genetic variation

  16. Data Mining SIAM Presentation

    Science.gov (United States)

    Srivastava, Ashok; McIntosh, Dawn; Castle, Pat; Pontikakis, Manos; Diev, Vesselin; Zane-Ulman, Brett; Turkov, Eugene; Akella, Ram; Xu, Zuobing; Kumaresan, Sakthi Preethi

    2006-01-01

    This viewgraph document describes the data mining system developed at NASA Ames. Many NASA programs have large numbers (and types) of problem reports.These free text reports are written by a number of different people, thus the emphasis and wording vary considerably With so much data to sift through, analysts (subject experts) need help identifying any possible safety issues or concerns and help them confirm that they haven't missed important problems. Unsupervised clustering is the initial step to accomplish this; We think we can go much farther, specifically, identify possible recurring anomalies. Recurring anomalies may be indicators of larger systemic problems. The requirement to identify these anomalies has led to the development of Recurring Anomaly Discovery System (ReADS).

  17. AECL present and future

    International Nuclear Information System (INIS)

    Foster, J.S.

    1975-08-01

    This is a history of Atomic Energy of Canada Limited with forecasts of its role in enabling Canada to meet a rapidly increasing share of her energy requirements from nuclear power. Its main activities will be research and development in support of contemporary and advanced CANDU (Canada Deuterium Uranium) nuclear power systems; research into other ways to provide energy and fissile materials; and investigation into applications for nuclear energy beyond the generation of electrical power. (Author)

  18. 2016 Research Final Presentation

    Energy Technology Data Exchange (ETDEWEB)

    Koskelo, EliseAnne Corinne [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-08-16

    These are slides which show an example of research at Los Alamos National Laboratory done by E.C. Koskelo to show college professors in the hopes of earning a research position or fellowship position. In summary, this researcher developed a new in-situ technique for the inspection of additively manufactured parts, created an algorithm which can correct "skewed" scans of angular parts/taken at oblique angles, and used AWS to detect hidden defects and thickness changes in aerospace composites.

  19. Energy Informatics Panel (Presentation)

    Energy Technology Data Exchange (ETDEWEB)

    Brodt-Giles, D.

    2012-06-01

    Designed to be the world's most comprehensive, open, and collaborative energy information network, Open Energy Information (OpenEI - openei.org) supplies essential energy data to decision makers and supports a global energy transformation. The platform, sponsored by the U.S. Department of Energy (DOE) and developed by the National Renewable Energy Laboratory (NREL), is intended for global contribution and collaboration.

  20. PowerPoint Presentation

    Indian Academy of Sciences (India)

    Table of contents. PowerPoint Presentation · Slide 2 · Slide 3 · Slide 4 · Slide 5 · Slide 6 · Slide 7 · Metal Oxides: Range of properties · Slide 9 · Slide 10 · Slide 11 · Slide 12 · Slide 13 · Slide 14 · Slide 15 · Slide 16 · Slide 17 · Slide 18 · Slide 19 · Slide 20 · Slide 21 · Slide 22 · Slide 23 · Slide 24 · Slide 25 · Slide 26 · Slide 27.

  1. PowerPoint Presentation

    Indian Academy of Sciences (India)

    PowerPoint Presentation · Slide 2 · Slide 3 · Slide 4 · Slide 5 · Slide 6 · Slide 7 · Slide 8 · Slide 9 · Slide 10 · Slide 11 · Slide 12 · 2-D Aromaticity · Condensed Aromatics and Hückel Rule · Slide 15 · Slide 16 · Slide 17 · Slide 18 · Slide 19 · Slide 20 · Slide 21 · Slide 22 · Slide 23 · Slide 24 · Slide 25 · Slide 26 · Slide 27 · Slide 28.

  2. United States panel presentations

    International Nuclear Information System (INIS)

    Young, H.

    1990-01-01

    The Department of Energy is supporting a number of programs directed at improving nuclear power's ability to compete by the mid 1990s in providing some of what will be urgently needed new baseload capacity, and at meeting both utility requirements and public goals. More specifically, we are co-funding demonstration by 1993 of the process for life extension of current nuclear plants. We are supporting the development of new ALWR designs which rely more on methods such as natural circulation, gravity, reduced power density, or the characteristics of materials, rather than engineered systems to provide safety. These designs will meet the criteria set forth in EPRI's Utility Requirements Documents. We have established a cost-sharing program to demonstrate the success of the nuclear plant standardization and licensing process by obtaining NRC certification by 1992 or 1993 of two evolutionary 1300MWe ALWR designs. We are also cost-sharing a program to certify by 1995 passively safe 600MWe ALWRs employing more natural safety features and modular construction. These programs will involve a rule-making hearing process. We are supporting the development and possible certification early in the next century of modular high temperature gas reactor and advanced liquid metal reactor plant designs. We are planning to demonstrate the early site approval licensing process through a cost-sharing arrangement with the private sector by 1995. In developing the National Energy Strategy, we are examining the issue of a fully satisfactory regulatory process, including the possibility of legislation codifying 10 CFR Part 52, limiting the possible delays associated with a potential second hearing and dealing with emergency planning issues before start of construction. We recently announced a restructured plan to develop a permanent waste repository by 2010. By 1995 we expect to have made significant progress in evaluating the suitability of Yucca Mountain. We expect to have selected a

  3. Country Presentation Tanzania

    International Nuclear Information System (INIS)

    KIFANGA, L.D.; GYIMBI, H.; MLOWOLA, V.; KASONGWA, M.

    2010-01-01

    Discusses overview of incidents and developments involving illicit trafficking of nuclear and other radioactive materials in Tanzania.13 cases have been recorded between 1996 and 2008. All cases occurred in Dar Es Salam. Police, customs and security staff intercepted the sources and culprits arrested. The latest incident occurred in May 2008 and involved illegal possession of a capsule labelled nuclear material (U-238). A total of 14 sources were seized . Types of sources seized were u-238, Caesium-137, Strontium-90 and Radium-226.

  4. Rhinosporidiosis: an unusual presentation.

    Science.gov (United States)

    Viswanatha, Borlingegowda

    2014-07-01

    Rhinosporidiosis is a chronic granulomatous disease that primarily affects the mucous membranes of the nose and nasopharynx. It is caused by Rhinosporidium seeberi. Clinically it presents as a reddish, bleeding, polypoid mass with a characteristic strawberry-like appearance on its surface, which is caused by the presence of mature sporangia. In the case described here, a 35-year-old man presented with a 6-month history of a slowly growing polypoid mass in his left nasal cavity. The surface of the mass was smooth, pale, and covered with nasal mucosa. It was attached to the nasal septum. Fine-needle aspiration cytology was suggestive of a parasitic cyst. The mass was excised with the use of local anesthesia. Histopathologic examination of the resected specimen revealed rhinosporidiosis. Prior to this diagnosis, the patient had not exhibited most of the typical clinical features that are suggestive of rhinosporidiosis. In the case of a nasal mass, a diagnosis of rhinosporidiosis is important to establish prior to any surgery because bleeding during and after surgery is usually profuse and can be life-threatening. The site of the excised mass should be cauterized to prevent recurrence.

  5. DOE financial assurance presentation

    International Nuclear Information System (INIS)

    Huck, R.

    1990-01-01

    The presentation topic is California's approach to license application review in meeting financial assurances for the proposed Ward Valley site. The purpose of the presentation is to provide information on specific financial assurance provisions contained in 10 CFR Part 61 and how California intends to satisfy those requirements. Also, as rate setter, California intends to demonstrate how it will assure allowable costs to the rate base though a financial prudency review. The key provisions of financial assurance are: 10 CFR Section 61.61 - This provision requires an applicant to demonstrate its ability to finance licensed activities; 10 CFR Section 61.62 - This provision requires an applicant to provide assurance that sufficient funds will be available for site closure and stabilization; and 10 CFR Section 61.63 - This provision requires an applicant to provide 'a copy of a binding arrangement, such as a lease, between the applicant and the disposal site owner, so that sufficient funds will be available to cover the costs of the institutional control period.' To assist California in its determination of financial assurance compliance to be demonstrated by the applicant for Part 61 requirements, is NUREG guidance document 1199 'Standard Format and Content of a License Application for a Low-Level Radioactive Waste (LLRW) Disposal Facility.' The detailed financial assurance provisions of NUREG 1199 are then embodied in NUREG 1200, 'Standard Review Plant for the Review of a License Application for a LLRW Disposal Facility.'

  6. Bad (Re)Presentations

    CERN Document Server

    Computer Security Team

    2013-01-01

    This time, we would like to address copyright violations (again) - but with a twist. While previous articles focussed on “Music, videos and the risk for CERN” or on software licences, the focus is now on using photos, music and images “found” on the Web for presentations, publications and web pages…   Just recently, a video produced for CERN and published on YouTube and Facebook used background music from a contemporary popular artist. However, the people responsible failed to obtain the appropriate permission to actually use that music. They thought that having bought it on iTunes was sufficient. But it was not: “buying” means you have the right to listen, but not the right for further distribution or re-publication. As a result, the videos were pulled from YouTube and Facebook. Similarly, how many of us integrate graphics and images “found” on the Web into our presentations?  How many of us...

  7. Advice presented on behalf of the commission of economic affairs, environment and territory about the project of 2003 financial law (no. 230), tome 4, ecology and sustainable development; Avis presente au nom de la commission des affaires economiques, de l'environnement et du territoire sur le projet de loi de finances pour 2003 (no. 230), tome 4, ecologie et developpement durable

    Energy Technology Data Exchange (ETDEWEB)

    Priou, Ch.

    2002-10-01

    This report presents in a detailed way the allocation of the financial supplies of the French environmental policy for 2003: 1 - constitution of a network of protected natural areas: the Natura 2000 network, the instruments at the service of this network (national and regional natural parks, natural reserves, the littoral and shores conservatory), enhanced protection and rehabilitation of sites and landscapes; 2 - water policy based on floods prevention: floods risk mitigation and reinforcement of peoples and goods protection, national solidarity funds for water and water agencies, fight against marine pollutions; 3 - security: prevention of natural disasters, prevention of technological risks (reinforcement of the expertise capacity of the national institute of industrial environment and risks, inspection of classified facilities, institute of radioprotection and nuclear safety), municipal wastes policy, fight against noise and atmospheric pollution; 4 - sustain of environmental policies and promotion of the sustainable development: elaboration of the environment charter, reinforcement of partnerships, combining the expertise capacity and the participation of the public. (J.S.)

  8. Unusual presentation of pheochromocytoma

    Directory of Open Access Journals (Sweden)

    Rajendra B. Nerli

    2014-01-01

    Full Text Available Pheochromocytomas are rare catecholamine-secreting tumors that arise from chromaffin tissue within the adrenal medulla and extra-adrenal sites. Due to the excess secretion of hormones, these tumors often cause debilitating symptoms and a poor quality-of-life. Although medical management plays a significant role in the treatment of pheochromocytoma patients, surgical excision remains the only cure. Pheochromocytoma usually has three classic symptoms-headache, sweating and heart palpitations (a fast heart beat in association with markedly elevated blood pressure (hypertension. Hormones such as catecholamines and metanephrines are measured in a 24 h urine collection and metanephrines may also be measured in the blood, to make a diagnosis of pheochromocytoma. If these are greater than 2 times the normal level, imaging studies are usually done to look at the adrenal glands. We report on three cases of pheochromocytoma, which had unusual presentation.

  9. O PRESENTE DE PROMETEU

    Directory of Open Access Journals (Sweden)

    Kassia Nobre

    2012-07-01

    Full Text Available O conteúdo elaborado neste artigo tem por objetivo discutir formas de conhecimento ao abordar, principalmente, o conhecimento reflexivo provindo das narrativas do jornalismo, por meio das reportagens. Invocando a tragédia do poeta grego Ésquilo, “Prometeu Acorrentado”, o conhecimento é apresentado como uma dádiva proibida aos mortais pelos deuses. O trabalho mostra que ainda nos tempos de hoje, o conhecimento é uma das buscas do ser humano e que as narrativas literárias e jornalísticas podem ser uma das respostas, contrariando o que diz a objetividade científica, quando o assunto é o presente de Prometeu.

  10. Living in the Present

    Directory of Open Access Journals (Sweden)

    Angela Barns

    2015-12-01

    Full Text Available This article presents the findings from a qualitative research project exploring eight women’s experiences of living with rheumatoid arthritis (RA. Through semistructured interviews, the women provided insights into the physical, emotional, and social impacts of RA and the “work” involved in negotiating its influence in the everyday life. In narrating their experiences of adapting to RA, the women express a common desire for “normalcy,” to return to a time and space before the disruption of RA. The women’s accounts also emphasized the interrelatedness between bodily experience and constructions of self, highlighting the corporeal nature of RA and the constant shaping and reshaping of personal meanings and values.

  11. Film Presentation: Die Urknallmaschine

    CERN Multimedia

    Carolyn Lee

    2010-01-01

    Die Urknallmaschine, an Austrian film by Gerd Baldauf, narrated by Norbert Frischauf (Alpha Österreich - ORF, 2009).  In CERN’s gigantic complex particles are accelerated to almost the speed of light, brought to collision and made to divide into even smaller particles. Public opinion of CERN’s research is also divided. Sceptics fear that black holes may be created. Might the goal to study the origin of the world lead to its destruction? The Austrian researcher Norbert Frischauf worked at CERN for many years. With his guidance it is possible to explore the world’s largest research centre, get a glimpse of the fascinating work the scientists do there and take a crash course in particle physics. Die Urknallmaschine will be presented on Friday, 25 June from 13:00 to 14:00 in the Main Auditorium. Language: German

  12. Presenting practice financial information.

    Science.gov (United States)

    Webster, Lee Ann H

    2007-01-01

    Medical practice leadership teams, often consisting primarily of physicians with limited financial backgrounds, must make important business decisions and continuously monitor practice operations. In order to competently perform this duty, they need financial reports that are relevant and easy to understand. This article explores financial reporting and decision-making in a physician practice. It discusses reports and tools, such as ratios, graphs, and comparisons, that practices typically include in their reports. Because profitability and cash flow are often the most important financial considerations for physician practices, reports should generally focus on the impact of various activities and potential decisions upon these concerns. This article also provides communication tips for both those presenting practice financial information and those making the decisions. By communicating effectively, these leaders can best use financial information to improve decision-making and maximize financial performance.

  13. Extratarsal presentation of chalazion.

    Science.gov (United States)

    Chang, Moohwan; Park, Jiwoong; Kyung, Sungeun E

    2017-12-01

    We report a case of atypical, extratarsal chalazion referred with a history of a chronic inflammatory mass found on the edge of the lower eyelid. A 3-year-old female developed a small mass on the medial side of the right lower lid in 4-month duration. She was seen by her ophthalmologist and the diagnosis of a chalazion was made. Over the ensuing one month with warm compression, the lesion subsided and the new lesion appeared away from the edge on the lateral eyelid 3 months ago. She underwent surgery and drainage was performed. We found a track, a proof of migration, on the lower tarsal conjunctiva in the medial side of the right eyelid during surgery. Long-term observation in chalazion may induce migration with tract and express as an atypical chalazion.

  14. Fleet DNA (Presentation)

    Energy Technology Data Exchange (ETDEWEB)

    Walkokwicz, K.; Duran, A.

    2014-06-01

    The Fleet DNA project objectives include capturing and quantifying drive cycle and technology variation for the multitude of medium- and heavy-duty vocations; providing a common data storage warehouse for medium- and heavy-duty vehicle fleet data across DOE activities and laboratories; and integrating existing DOE tools, models, and analyses to provide data-driven decision making capabilities. Fleet DNA advantages include: for Government - providing in-use data for standard drive cycle development, R&D, tech targets, and rule making; for OEMs - real-world usage datasets provide concrete examples of customer use profiles; for fleets - vocational datasets help illustrate how to maximize return on technology investments; for Funding Agencies - ways are revealed to optimize the impact of financial incentive offers; and for researchers -a data source is provided for modeling and simulation.

  15. Country Presentation Angola

    International Nuclear Information System (INIS)

    Cardoso, L.; Ferreira, Edson; Goma, A.

    2010-01-01

    The Republic of Angola joined the IAEA in September 1999. Since then, the country started by designing, promoting and developing its programme on nuclear and technology through the Unit for Nuclear Science and Technology created by the Ministry of Science and Technology.The Angolan Atomic Law was approved on June 28 and published on September 05, 2007.Radioactive Waste Every person who is licensed to generate, keep or manage radioactive waste shall be responsible for the safe management of radioactive waste generated by the practice or source for which he/she is authorized. No person shall transport any radioactive material, radioactive substance or radiation generator on any vessel or boat within the territorial waters or the exclusive economic zone of Angola; on any aircraft within the airspace of Angola; or any means of land transport without authorization from the Regulatory Authority of Atomic Energy

  16. Proceedings of a workshop on the development and evaluation of habitat suitability criteria: A compilation of papers and discussions presented at Colorado State University, Fort Collins, Colorado, December 8-12, 1986

    Science.gov (United States)

    Bovee, Ken; Zuboy, J.R.

    1988-01-01

    for developing and evaluating habitat suitability criteria. Participation in this workshop was largely by invitation only. The objective was to obtain insights into problems and possible solutions to criteria development, from the perspective of professionals closely involved with the subject. These proceedings of that workshop are intended to supplement the information contained in Instream Flow Information Paper 21, "Development and Evaluation of Habitat Suitability Criteria for Use in the Instream Flow Incremental Methodology." The workshop was closely arranged in five sessions, roughly following the outline of Information Paper 21. The first session dealt with various aspects of study design and how they can influence the outcome of a study. Session two investigated techniques for developing criteria from professional judgment, and some of the problems encountered when personal or agency prejudice enters the picture. Session three concentrated on field data collection procedures, whereas session four examined methods of converting field data into curves. Field verification studies were discussed in session five. Each presentation in the workshop was followed by a question and answer period of 15 to 30 minutes. These discussions were recorded, transcribed, and appended to the end of each paper in these proceedings. We have attempted to capture the essence of these discussions as accurately as possible, but hope that the reader can appreciate the difficulty in translating a free-ranging discussion (from a barely audible tape) to something that makes sense in print. These question and answer sessions constitute the peer review for each of the papers. This provides the reader with the unique opportunity to review the interactions between authors and reviewers.

  17. Atypical presentations of Wolframs syndrome

    Directory of Open Access Journals (Sweden)

    S Saran

    2012-01-01

    Full Text Available Background: Wolfram syndrome is a rare hereditary or sporadic neurodegenerative disorder also known as DIDMOAD. The classically described presentation is of insulin-dependent diabetes, followed by optic atrophy, central diabetes insipidus, and sensory neural deafness. Also included are less well-described presentations of Wolframs syndrome. We here present three cases of atypical presentation of this syndrome. Case 1: A 15-year-old boy with insulin-dependent diabetes was presented for evaluation of depressive symptoms associated with suicidal tendency. Neuropsychiatric manifestations are described with Wolframs syndrome, and wolframin gene, in recessive inheritance, is associated with psychiatric illnesses without other manifestations of Wolframs syndrome. Case 2: A 17-year-old diabetic boy on insulin with good control of blood sugar presented for evaluation of delayed puberty. Central hypogonadism and other anterior pituitary hormone dysfunctions are the less publicized hormone dysfunctions in Wolframs syndrome. Case 3: A 23-year-old female who was on insulin for diabetes for the past 14 years, got admitted for evaluation of sudden loss of vision. This patient had developed a vitreous hemorrhage and, on evaluation, was found to have optic atrophy, sensory neural hearing loss, and diabetes insipidus, and presented differently from the gradual loss of vision described in Wolframs syndrome. Conclusion: Wolframs syndrome being a multisystem degenerative disorder can have myriad other manifestations than the classically described features. Neuropsychiatric manifestations, depression with suicidal risk, central hypogonadism, and secondary adrenal insufficiency are among the less well-described manifestations of this syndrome.

  18. Early Detection of Fetal Malformation, a Long Distance Yet to Cover! Present Status and Potential of First Trimester Ultrasonography in Detection of Fetal Congenital Malformation in a Developing Country: Experience at a Tertiary Care Centre in India

    Directory of Open Access Journals (Sweden)

    Namrata Kashyap

    2015-01-01

    Full Text Available Background. Early detection of malformation is tremendously improved with improvement in imaging technology. Yet in a developing country like India majority of pregnant women are not privileged to get timely diagnosis. Aims and Objectives. To assess the present status and potential of first trimester ultrasonography in detection of fetal congenital structural malformations. Methodology. This was a retrospective observational study conducted at Sanjay Gandhi Postgraduate Institute of Medical Sciences. All pregnant women had anomaly scan and women with fetal structural malformations were included. Results. Out of 4080 pregnant women undergoing ultrasound, 312 (7.6% had fetal structural malformation. Out of 139 patients who were diagnosed after 20 weeks, 47 (33.8% had fetal structural anomalies which could have been diagnosed before 12 weeks and 92 (66.1% had fetal malformations which could have been diagnosed between 12 and 20 weeks. Conclusion. The first trimester ultrasonography could have identified 50% of major structural defects compared to 1.6% in the present scenario. This focuses on the immense need of the hour to gear up for early diagnosis and timely intervention in the field of prenatal detection of congenital malformation.

  19. Medical resources presentation on WWW

    Directory of Open Access Journals (Sweden)

    Anamarija Rožić-Hristovski

    1997-01-01

    Full Text Available Librarians are confronted with new challanges offered by currently developing information technologies. There are more and more information sources in medicine that comprise bibliographic and textual databases, various books and textbooks. These are available on different computer media. The task of librarians is to introduce scientists, health care professionals and students to digital library and present ali available sources, so that they can choose the proper solution for their information needs. CMK has decided to design a home page to present its services and even more medical information resources accessible locally, on the local network and on the Internet.

  20. The laryngocele; case presentation

    Directory of Open Access Journals (Sweden)

    Gabriel V. Berteșteanu

    2016-05-01

    Full Text Available Laryngocele is a rare pathology, but because of their clinical evolution and the symptoms they generate, they should always be considered as a differential diagnosis when investigating neck masses. A laryngocele is basically a herniation of the mucosa of the laryngeal ventricle (Morgagni's ventricle arising usually from the saccular region. This herniation may remain confined to the larynx - in which case the laryngocele is internal- or expand through the thyro-hyoid membrane into the structures of the neck - thus being called an external laryngocele. Usually the laryngocele has both an internal and external component thus being a mixed laryngocele. Diagnosis of laryngoceles still relies heavily on clinical signs such as tympanism, easily depressible neck mass, indirect laryngoscopy, but is now simplified by imagistic investigations (ultrasound, CT and MRI. However, the treatment of this condition is exclusively surgical and consists of total excision of the laryngocele, as well as proper identification of the point of origin from the saccule and also the final suture of the breach in order to prevent recurrence. Investigation of possible causes of obstruction of the laryngeal ventricle should always be performed (because of the possibility of an underlying malignancy as well as a follow-up protocol of the patient, given the risk of relapse. We present a recently diagnosed case of a 32 year old man with mixed laryngocele, which we have operated in our clinic.

  1. Endometriosis Presenting as Hydronephrosis

    Directory of Open Access Journals (Sweden)

    Ahmed Bakheet Zaharani

    2005-01-01

    Full Text Available The most serious urological complication of endometriosis is hydronephrotic renal atrophy secondary to ureteric involvement. As only half of these patients are symptomatic, it is commonly diagnosed late and more by the clinicians awareness and suspicion of this entity. We report a case of an unmarried young female who presented primarily with left loin pain of 2-year duration. She was found to have lower ureteric stricture by an IVU done by her referring doctor. Further workup at our center showed that she had pelvic endometriosis with hydronephrosis secondary to extrinsic ureteric endometriosis. She had a first-degree relative with the same disease. She had no menstrual problems. Diagnostic laparoscopy, biopsy of the lesion, ureteric dilatation with stenting, along with hormonal treatment was given to her as first line of treatment. There was no improvement of the ureteric obstruction even after 6 months of treatment. Finally, surgical excision of the endometrioma, left oophorectomy, along with resection of the ureteric stricture with uretero-ureterostomy was done. This case report includes details of her further management and outcome along with a brief review of literature.

  2. Voice integrated presentation system

    Science.gov (United States)

    Dumas, N. S.

    1984-06-01

    An audiographic telephone conferencing system between a plurality of parties or users either directly connected or through a piece of apparatus known as a meet me bridge over voice grade telephone lines. Each user has a programmed personal computer which controls a programmable or smart modem, cassette recorder/player, and speakerphone. A protocol is implemented by the software, i.e., the computer program, in each of the computers which puts its respective modem in a listening mode to monitor the phone line at all times. The computer is further programmed and includes a memory for storing and transmitting graphics presently on hand to other user(s) via the modem during a teleconference or alternatively receive graphics from another user, or it can switch to an external graphics program to make new or modify existing graphic images. However, one is unable to speak on the telephone line while a graphic is being transmitted during a teleconference due to the fact that voice alternates with graphic transmissions.

  3. IKONOS: future and present

    Science.gov (United States)

    Schaap, Niek

    2003-04-01

    The IKONOS satellite has been operational since January 2000 and was the first commercial satellite collecting imagery with 1 meter resolution. The current life expectancy of the satellite is 10 years. Since the launch, Space Imaging Inc. (the owner of the satellite) supplied IKONOS imagery to users in many vertical markets, such as: agriculture, defense, oil & gas and telecommunications. This oral presentation will give comprehensive information about IKONOS and the future: * Block II, the successor of IKONOS. Space Imaging expects to launch in 2004 a new high-resolution satellite, ensuring both continuity and (for some years) a tandem operation with IKONOS, greatly improving the availability of imagery. * Space Imaging affiliates. IKONOS imagery collected, processed and sold by regional affiliates. These regional affiliates are strategically located around the world, like Japan Space Imaging (Tokyo), Space Imaging Middle East (Dubai) and Space Imaging Eurasia (Ankara, Turkey). * Technical briefing IKONOS. IKONOS (compared to other commercial high-resolution satellites) has superior collection capabilities. Due to, the higher orbit altitude, local reception of the imagery, bi-directional scanning and the high agility of the satellite, is the IKONOS satellite capable to collect the imagery relative quickly.

  4. Technical presentation of SCR

    CERN Multimedia

    FI Department

    2008-01-01

    SCR Société des Composants Record, Montierchaume, France Monday 20 October 2008 from 9:45 to 12:00 – Room A Main Building (Bldg. 61/1-017) http://www.scr.fr SCR develops, manufactures and markets plastic dielectric capacitors (polypropylene, polyester, Teflon) for use in various applications: audio amplifiers, high-end loudspeakers, fans and extractors (multi-capacitance capacitors), pulsed lasers, flash lamps, defibrillators, beacons, power supplies, converters for rail traction drives, railway signalling devices, voltage dividers and multipliers, high voltage laboratories, etc. The company is renowned for its precision wire-wound resistors for use in power electronics and consumer electronics marketed under the SETA brand name. SCR is also experienced in the design and production of electronic circuits for various applications, such as speed variators for mono and three-phase motors, dimmers, passive filters for audio speakers, etc. Contact : M. Urs V. Rölli, e-mail: mailto:info@technictrade.ch.

  5. Vitreous floaters (Conference Presentation)

    Science.gov (United States)

    Kershaw, K.; Nguyen, Derek; Yee, Kenneth; Nguyen, Justin A.; Harrington, Michael G.; Sebag, Jerry

    2017-02-01

    BACKGROUND: Vitreous opacities and posterior vitreous detachment (PVD) disturb vision by degrading contrast sensitivity (AJO 172:7-12, 2016). Increased light scattering is the presumed mechanism. To test this hypothesis, dynamic light scattering (DLS) was performed on excised vitreous of patients with clinically significant floaters, and compared to macular pucker controls. METHODS: Undiluted, unfixed vitreous was procured during 25-gauge vitrectomy in 14 subjects (age = 59 +/- 6.6 years) with clinically significant vitreous floaters, and 6 controls (age = 66.5 +/- 8.7 years; P = 0.10) with macular pucker. Total protein concentration was determined by fluorescent Quant-iTTM protein assay kit (Invitrogen/Molecular Probes, Eugene, OR) with bovine serum albumin (0500 ng/ml) as a standard. Fluorescence (excitation at 470 nm and emission at 570 nm) was measured using a Gemini XPS Dual-Scanning Microplate Spectrofluorometer and data analyzed using SoftMax Pro software (Molecular Devices, Sunnyvale, CA). DLS (NS300, Malvern Instruments, Westborough, MA) measurements were performed in each specimen after 10-fold dilution in phosphate buffered saline to optimize concentration in each specimen and determine the mean number of particles, the particle size distributions, and the average particle sizes. RESULTS: Total protein concentration in vitreous specimens trended higher in macular pucker controls (1037 +/- 1038 μg/mL) than eyes with vitreous floaters (353.7 +/- 141.1 μg/mL P = 0.08). When normalized to total protein concentration, the number of particles in vitreous from floater eyes was more than 2-fold greater than controls (P AJO 172:7-12, 2016). DLS could elucidate the underlying molecular abnormalities in patients afflicted with bothersome vitreous floaters and help develop clinical tools to better measure vitreous floaters as well as test the efficacy of various therapies.

  6. Presentation : Spatial Analysis and GEOmatics

    Directory of Open Access Journals (Sweden)

    Didier Josselin

    2006-10-01

    Full Text Available SAGEO is the annual International Conference on Spatial Analysis and GEOmatics. It aims to:  present recent and high quality research in the field of Geomatics and Spatial Analysis, bring together researchers from various disciplines, provide an exchange platform on research and development in Geomatics, on a national and international level, for public or private bodies. SAGEO is a good opportunity for two complementary research networks to meet and to discuss their points of view on spatial...

  7. Texts of presentation

    Energy Technology Data Exchange (ETDEWEB)

    Magnin, G.; Vidolov, K.; Dufour-Fallot, B.; Dewarrat, Th.; Rose, T.; Favatier, A.; Gazeley, D.; Pujol, T.; Worner, D.; Van de Wel, E.; Revaz, J.M.; Clerfayt, G.; Creedy, A.; Moisan, F.; Geissler, M.; Isbell, P.; Macaluso, M.; Litzka, V.; Gillis, W.; Jarvis, I.; Gorg, M.; Bebie, B.

    2004-07-01

    Implementing a sustainable local energy policy involves a long term reflection on the general interest, energy efficiency, distributed generation and environmental protection. Providing services on a market involves looking for activities that are profitable, if possible in the 'short-term'. The aim of this conference is to analyse the possibility of reconciling these apparently contradictory requirements and how this can be achieved. This conference brings together the best specialists from European municipalities as well as important partners for local authorities (energy agencies, service companies, institutions, etc.) in order to discuss the public-private partnerships concerning the various functions that municipalities may perform in the energy field as consumers and customers, planners and organizers of urban space and rousers as regards inhabitants and economic players of their areas. This document contains the summaries of the following presentations: 1 - Performance contracting: Bulgarian municipalities use private capital for energy efficiency improvement (K. VIDOLOV, Varna (BG)), Contracting experiences in Swiss municipalities: consistent energy policy thanks to the Energy-city label (B. DUFOUR-FALLOT and T. DEWARRAT (CH)), Experience of contracting in the domestic sector (T. ROSE (GB)); 2 - Public procurement: Multicolor electricity (A. FAVATIER (CH)), Tendering for new green electricity capacity (D. GAZELEY (GB)), The Barcelona solar thermal ordinance (T. PUJOL (ES)); 3 - Urban planning and schemes: Influencing energy issues through urban planning (D. WOERNER (DE)), Tendering for the supply of energy infrastructure (E. VAN DE WEL (NL)), Concessions and public utility warranty (J.M. REVAZ (CH)); 4 - Certificate schemes: the market of green certificates in Wallonia region in a liberalized power market (G. CLERFAYT (BE)), The Carbon Neutral{sup R} project: a voluntary certification scheme with opportunity for implementation in other European

  8. Development of a method for calculating the cost of the program for decommissioning of nuclear power plants. Prognosis of future costs for the authorities including the corresponding net present value. Analysis performed May 6-7 and June 8 2004

    International Nuclear Information System (INIS)

    Borg, Lorens; Lichtenberg, Steen; Lindskog, Staffan

    2004-09-01

    The aim of this report is to present a calculation of the authorities' total future costs in terms of their activities to monitor a safe and prudent decommission of the power plants, including the long term storage of the used fuel. An assessment of the inherent uncertainty in this estimate is also made. The study forms an integrated part of the total monitoring into the financial assessment of the whole programme of decommissioning and demolition of the Swedish nuclear power plants that continuously is made by SKI. Hence, the estimate is presented with the additional function of supporting SKI's annual calculations of fees and contingencies in accordance with the Swedish Finance Act. Main result The expected Net Present Value of the authorities' costs as at January 2004 price level have consequently been estimated as follows: Mean Value (M): 2303 MSEK Standard deviation (S): 538 MSEK 8 This result tallies with the corresponding prognoses for the last two years. An additional clarification of a number of key figures resulted in some reduction of the total Net Present Value. By way of supplement to this main result, the undiscounted costs have been estimated (calculation 2). Besides, a tentative estimate has also been made by incorporating the official view on the future development on real rate of return in a long time perspective (calculation 3). The uncertainty of the result is significant in terms of the final budget figures and of the scale of the supplementary amounts in those situations where the budgets must be prudent and conservative. There may be a potential for further reduction of the current uncertainty in that the greatest causes of uncertainty now have been identified and ranked in order of priority. The greatest causes of uncertainty are set out in the table below. No. Cause of uncertainty Uncertainty group 1 Priority 2 1 Correction allowing for the uncertainty of the real interest rate N 55 % 2 Productivity E2 8 % 3 Uncertainty in the current base

  9. LA CREACION DE EMPRESAS DE ECONOMIA SOCIAL EN EL MODELO DE DESARROLLO LOCAL: REFLEXIONES SOBRE LA DIVERGENCIA ACTUAL DEL CASO VALENCIANO / THE CREATION OF SOCIAL ECONOMY COMPANIES IN THE MODEL OF LOCAL DEVELOPMENT: REFLECTIONS ON THE PRESENT CASE VALENCIAN DIVERGENCE

    Directory of Open Access Journals (Sweden)

    RICARD CALVO PALOMARES

    2011-05-01

    Full Text Available La hipótesis central de nuestro artículo gira en torno al papel asumido por el modelo de desarrollo local implantado en España desde la década de los 80 en el proceso de creación de empresas, y en concreto en el proceso de creación de empresas de Economía Social. Plantea la reflexión sobre cómo en sus inicios el modelo, apostaba encarecidamente por el fomento y la constitución de cooperativas como política activa de empleo, y en cómo en la actualidad, ha abandonado esta línea de actuación en favor de otras formas jurídicas. Para ello, partiremos del análisis de los datos oficiales existentes sobre la evolución de los dos modelos en la Comunitat Valenciana, poniendo de manifiesto la tendencia a la baja sufrida en la promoción de constitución de entidades de Economía Social y por el contrario el continuo crecimiento de Agencias Locales de Empleo y Desarrollo. Finalmente concluiremos el artículo proponiendo una serie de factores, que a nuestro entender han sido los determinantes de este proceso. / The central hypothesis of this article focuses on the role played by the local development model implemented in Spain since the 80//////s in the process of business creation, and specifically in the creation of social economy enterprises. Raises the debate on how the model in its infancy, argued strongly for the promotion and development of cooperatives as active employment policy, and how at present, has abandoned this line of action in favor of other legal forms. For this, the analysis of existing official data on the evolution of the two models in the Valencia region, shown by the downward trend experienced in the promotion of cooperatives and on the contrary, the continuous growth of Local Agencies Employment and Development. Finally propose a number of factors, which we believe are the determinants of this process.

  10. Advice presented on behalf of the commission of foreign affairs about the project of 2003 financial law (no. 230), tome 5, ecology and sustainable development; Avis presente au nom de la commission des affaires etrangeres sur le projet de loi de finances pour 2003 (no. 230), tome 5, ecologie et developpement durable

    Energy Technology Data Exchange (ETDEWEB)

    Guillet, J.J.

    2002-10-01

    The aim of this advice is to make an annual status of the French enforcement of the international commitments for the sustainable development: 1 - from the Rio summit to the Johannesburg one: the worldwide awareness, the progresses made after each international summit, the UN framework of dialogue and action, the diverging interests and opinions, the role and action of France; 2 - the international commitments for the sustainable development: the Johannesburg commitments, the promotion of the good governance, the fight against the emission of greenhouse gases, the access to water and energy; 3 - the French commitment for the sustainable development: the environment charter, the role of the European Union, a plurality of actors, the public-private partnership, the sustainable development stakes for the overseas departments and territories (DOM-TOM); 4 - the instruments and financial supplies of the ministry of ecology and sustainable development. (J.S.)

  11. Presentation

    Directory of Open Access Journals (Sweden)

    Theresa Adrião

    2009-06-01

    Full Text Available O vol. 19, número 32, da Revista Educação Teoria e Prática apresenta o Dossiê Gestão Educacional: Interfaces entre o Público e o Privado para a Oferta Educacional, cuja origem se deve ao seminário de mesmo nome organizado pelo Grupo de Estudos e Pesquisas em Política Educacional (GREPPE em fevereiro deste ano. Os textos aqui apresentados ilustram as reflexões de pesquisadores e atores sociais sobre formas pelas quais o setor privado, em suas distintas manifestações, e o setor público vem interagindo na produção de estratégias e políticas relativas à educação básica. Em seu conjunto apresentam-se como esforços de reflexão sobre iniciativas concretamente percebidas, especialmente verificadas a partir dos ajustes sofridos na gestão pública quando da generalização, na década de 1990, dos postulados da lógica gerencial. Período no qual também se acentua no Brasil a expansão do acesso à educação fundamental por meio da descentralização para os governos locais da responsabilidade sobre esta expansão.

  12. present

    African Journals Online (AJOL)

    in the 1969/70 academic calendar. English became the medium of instruction from Standard 5 into university education and was made a compulsory subject of study throughout the education system ...... assumptions led to the abandonment of the use of vernaculars in class. Our study also established that the exercise is ...

  13. Presentation

    OpenAIRE

    Meléndez Dobles, Silvia

    2016-01-01

    Las más de las veces, la historia y la geografía han transitado juntas un mismo camino. Los orígenes de la humanidad en el África, su expansión por toda la superfcie terrestre y la conversión de una simple especie de primates en civilización son procesos inequívocamente históricos y geográfcos. Estas y otras muchas razones hacen entendible que ambas disciplinas hayan interactuado en un espacio/tiempo aparentemente inseparable. Las más de las veces, la historia y la geografía han transitado...

  14. Rare presentation of AICA syndrome.

    Science.gov (United States)

    Shabbir, Syed H; Nadeem, Faryal; Labovitz, Daniel

    2018-01-23

    We report a rare presentation of an anterior inferior cerebellar artery (AICA) infarct in a 74-year-old woman with acute-onset nausea, vomiting, vertigo and gait instability long before the full onset of symptoms and a negative MRI on admission. Over the next several days the patient developed left facial weakness, numbness, hypoacusis, and limb and gait ataxia, and was found to have acute infarcts of the left pons and cerebellar peduncle consistent with an AICA syndrome. We discuss this rare stepwise presentation in AICA syndrome and possible underlying pathophysiology. Such patients at risk for cerebrovascular disease should undergo a careful history, exam and follow-up, even with negative MRI findings, as their symptoms may precede a serious vascular event. © BMJ Publishing Group Ltd (unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  15. Site selection: Past and present

    International Nuclear Information System (INIS)

    Tilford, N.R.

    1994-01-01

    Site selection has been going on since the earliest times. The process has evolved through the Industrial Revolution to the present period of exploding population and environmental awareness. Now the work must be done both with increasing sophistication and greater transparency. Modern techniques for site selection have been developed during the last two decades or so, utilizing a teachable body of knowledge and a growing literature. Many firms and individuals have contributed to this growing field. The driving force has been the need for such a process in siting and licensing of critical facilities such as nuclear power plants. A list of crucial, documented steps for identifying social impacts and acceptability are provided. A recent innovation is the self-selection method developed by government. The Superconducting Supercollider serves as an example of this approach. Geological or geologically dependent factors often dominate the process. The role as engineering and environmental geoscientists is to provide responsible leadership, consultation, and communication to the effort

  16. Meningitis, Clinical Presentation of Tetanus

    Directory of Open Access Journals (Sweden)

    Anna Moniuszko

    2015-01-01

    Full Text Available Background. Tetanus is an acute disease caused by a neurotoxin produced by Clostridium tetani. Tetanus immunization has been available since the late 1930s but sporadic cases still occur, usually in incompletely vaccinated or unvaccinated individuals. Case Report. An elderly previously vaccinated female contracted tetanus following foot injury. Clinically she presented with meningitis causing diagnostic and therapeutic delays. Why Should Physician Be Aware of This? Even in developed countries the differential diagnosis of meningitis, especially in the elderly, should include tetanus. Treatment in intensive care unit is required. General population might benefit from vaccine boosters and education on this potentially fatal disease.

  17. Latest developments on fibered MOPA in mJ range with hollow-core fiber beam delivery and fiber beam shaping used as seeder for large scale laser facilities (Conference Presentation)

    Science.gov (United States)

    Gleyze, Jean-François; Scol, Florent; Perrin, Arnaud; Gouriou, Pierre; Valentin, Constance; Bouwmans, Géraud; Hugonnot, Emmanuel

    2017-05-01

    The Laser Megajoule (LMJ) is a French large scale laser facility dedicated to inertial fusion and plasma physics research. LMJ front-ends are based on fiber laser technology at nanojoule range [1]. Scaling the energy of those fiber seeders to the millijoule range is a way to upgrade LMJ's front ends architecture and could also be used as seeder for lasers for ELI project for example. However, required performances are so restrictive (optical-signal-to-noise ratio higher than 50 dB, temporally-shaped nanosecond pulses and spatial single-mode top-hat beam output) that such fiber systems are very tricky to build. High-energy fiber amplifiers In 2015, we have demonstrated, an all-fiber MOPA prototype able to produce a millijoule seeder, but unfortunately not 100% conform for all LMJ's performances. A major difficulty was to manage the frequency modulation used to avoid stimulated Brillouin scattering, to amplitude modulation (FM-AM) conversion, this limits the energy at 170µJ. For upgrading the energy to the millijoule range, it's necessary to use an amplifier with a larger core fiber. However, this fiber must still be flexible; polarization maintaining and exhibit a strictly single-mode behaviour. We are thus developing a new amplifier architecture based on an Yb-doped tapered fiber: its core diameter is from a narrow input to a wide output (MFD 8 to 26 µm). A S² measurement on a 2,5m long tapered fiber rolled-up on 22 cm diameter confirmed that this original geometry allows obtaining strictly single-mode behaviour. In a 1 kHz repetition rate regime, we already obtain 750 µJ pulses, and we are on the way to mJ, respecting LMJ performances. Beam delivery In LMJ architecture the distance between the nanojoule fiber seeder and the amplifier stages is about 16 m. Beam delivery is achieved with a standard PM fiber, such a solution is no longer achievable with hundreds of kilowatt peak powers. An efficient way to minimize nonlinear effects is to use hollow-core (HC

  18. Acquisitions and Collection Development Round Table Proceedings Presented by the Committee on Resource Sharing and Coordinated Acquisitions of the Long Island Library Resource Council (Farmingdale, New York, June 1, 1994).

    Science.gov (United States)

    Gerstein, Christine Wondolowski, Comp.

    Topics addressed at this round table discussion on resource sharing and cooperative acquisitions and collection development include the budget crisis, librarian-faculty collection development cooperation, weeding as a collection development function, and preservation through binding. This volume is composed of abstracts of each round table topic…

  19. Opinion presented on behalf of the Economic Affairs Commission on the Finance bill for 2011 (n. 2824), volume 2 Ecology, Sustainable Development and Land Planning, industry and energy; Avis presente au nom de la Commission des Affaires Economiques sur le projet de loi de finances pour 2011 (n. 2824), tome 2 ecologie, developpement et amenagement durables industrie et energie

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2010-07-01

    In her introduction, the author gives a description of the difficult context and situation faced by the industrial sector in France, notably because of the growing activity of emerging countries like China, India or Brazil, but also because of the weakness of research industrial valorization and of the innovation policy (losing the manufacturing capacity leads to losing the capacity for innovation). Then, after a critic of the current policy (reform of the professional tax, a boosting plan with limited results), she comments the contents of public programmes concerning firm and job development, energy, the steering of ecology, energy, sustainable development and sea policies, research in energy and sustainable development and land planning. She comments ways and tools aimed at supporting industrial jobs through innovation: the FSI (strategic investment fund), the competitiveness poles, specific aids to small and medium sized enterprises, tax credit related to research activities. She addresses the energy sector, questioning the French supremacy in the nuclear energy and the increase of electricity price, and criticizing the management of the development of renewable energies (high expenses for no industrial development)

  20. Summary of presentations and discussions

    International Nuclear Information System (INIS)

    Takeuchi, Mitsuo

    2008-01-01

    In December 2007, the Forum on Stakeholder Confidence discussed its theme entitled 'Link between research, development and demonstration (RD and D) and stakeholder confidence'. It was remarked that regulators need a technical demonstration to aid in evaluating the safety case. Local stakeholders appreciate the opportunity to visualise technological arrangements. In both cases, demonstration adds to confidence in the feasibility of solutions. Some believe there is an important role for analogues in communication with stakeholders, if handled with integrity. To explore and benchmark current practices, it was decided to hold a topical session at the 9. regular meeting of the FSC on 4 June 2008 regarding the use of analogues for confidence building. The session opened with an introductory presentation by the session rapporteur. This incorporated input provided for the purpose by FSC members in cooperation with their country's representative to the NEA RWMC 'Integration Group on the Safety Case'. Three speakers then presented the various uses of analogues by implementers, regulators and scientists to build their own confidence; a fourth speaker dealt with the experience of using natural analogues in public information. The presentations addressed the use of analogues in the field of geological disposal of high-level waste (HLW) and long-lived intermediate level (ILW-LL) radioactive waste. Then the FSC participants split into two working groups for discussion. The outcome of these discussions was reported in plenary on 6 June 2008 and it was agreed to publish proceedings of the session. The present summary, prepared by the session rapporteur with input from the NEA Secretariat, captures the main points heard in the course of the event. It combines data from the formal presentations and remarks made in discussion. The latter represent viewpoints expressed by a group whose primary focus is not natural analogues but rather stakeholder interests. The

  1. General presentation including new structure

    Science.gov (United States)

    Soons, A.

    2002-12-01

    Electrical, electronic and electro-mechanical components play an essential role in the functional performance, quality, life cycle and costs of space systems. Their standardisation, product specification, development, evaluation, qualification and procurement must be based on a coherent and efficient approach, paying due attention to present and prospective European space policies and must be commensurate with user needs, market developments and technology trends. The European Space Components Coordination (ESCC) is established with the objective of harmonising the efforts concerning the various aspects of EEE space components by ESA. European national and international public space organisations, the component manufacturers and the user industries. The goal of the ESCC is to improve the availability of strategic EEE space components with the required performance and at affordable costs for institutional and commercial space programmes. It is the objective of ESCC to achieve this goal by harmonising the resources and development efforts for space components in the ESA Member States and by providing a single and unified system for the standardisation, product specification, evaluation, qualification and procurement of European EEE space components and for the certification of components and component manufacturers.

  2. Source rock hydrocarbons. Present status

    International Nuclear Information System (INIS)

    Vially, R.; Maisonnier, G.; Rouaud, T.

    2013-01-01

    This report first presents the characteristics of conventional oil and gas system, and the classification of liquid and gaseous non conventional hydrocarbons, with the peculiar case of coal-bed methane. The authors then describe how source rock hydrocarbons are produced: production of shale oils and gases (horizontal drilling, hydraulic fracturing, exploitation) and of coal-bed methane and coal mine methane. In the next part, they address and discuss the environmental impact of source rock hydrocarbon production: installation footprint, water resource management, drilling fluids, fracturing fluids composition, toxicity and recycling, air pollution, induced seismicity, pollutions from other exploitation and production activities. They propose an overview of the exploitation and production of source rock gas, coal-bed gas and other non conventional gases in the world. They describe the current development and discuss their economic impacts: world oil context and trends in the USA, in Canada and other countries, impacts on the North American market, on the world oil industry, on refining industries, on the world oil balance. They analyse the economic impacts of non conventional gases: development potential, stakes for the world gas trade, consequence for gas prices, development opportunities for oil companies and for the transport sector, impact on CO 2 emissions, macro-economic impact in the case of the USA

  3. Draft Workshop Summary and Presentations

    International Nuclear Information System (INIS)

    Houssin, Didier; ); Tam, Cecilia; ); Cameron, Ron; ); Paillere, Henri; ); Lisann, Beth; Ehlert, Andreas; Kaufer, Barry; Decobert, Veronique; Beutier, Didier; Crepin, Anne; Aurela, Jorma; Baritaud, Manuel; ); Rooke, Oliver; Blundell, Neil; ); Shropshire, David; Noren, Bjarne; Blundell, Neil; ); Dujardin, Thierry; )

    2014-01-01

    the electricity market reform in the UK); Session 4: Nuclear regulation and safety (Regulation for new build and new comer countries and Fukushima Safety Action Plan; WANO's contribution to strengthen nuclear safety worldwide; Strengthening Good Practice within Nuclear Safety post Fukushima-Daiichi); Session 5: Key Message for the Road-map update (Outline current status of nuclear technology development and need for additional R and D to address increased safety requirements; Provide an updated vision for nuclear energy's role in a low carbon energy system; Identify barriers and actions needed to accelerate the development and deployment of nuclear technologies to meet the Road-map vision; Identify and share lessons learned and best practices in nuclear regulation, front and back end fuel cycle practices, construction and financing. This document brings together the available presentations (slides) given at this workshop: 1 - Road-map overview and role of nuclear in IEA scenarios (Cecilia Tam, IEA); 2 - The Direction Of The 2014 Nuclear Road-map (Ron Cameron, OECD/NEA); 3 - Technology development needs for nuclear energy, 1.a: Reactor technology (Henri Paillere, OECD/NEA); 4 - IEA/NEA Nuclear Technology Road-map Update (Beth Lisann, US-DoE); 5 - Update of the Nuclear Energy Technology Road-map - Nuclear Decommissioning (Andreas Ehlert, E-On); 6 - Overcoming barriers to nuclear build - other than financing (Veronique Decobert, Westinghouse); 7 - Development of the supply chain: relying on local industrial involvement (Didier Beutier, Areva); 8 - Training and capacity development needs (Jorma Aurela, Finnish Ministry of Employment and the Economy); 9 - Key conditions for successful Nuclear new build financing (Anne Crepin, Areva); 10 - Regulation for New Build and Newcomers, IAEA Nuclear Safety Action Plan (David Shropshire, IAEA); 11 - WANO's contribution to strengthen nuclear safety worldwide (Bjarne Noren, WANO); 12 - Strengthening Good Practice within Nuclear Safety

  4. Transversalidad de conceptos de educación ambiental para un desarrollo sostenible presentes en la legislación argentina Environmental education as a crosscutting issue for sustainable developement concepts included in Argentine regulations

    Directory of Open Access Journals (Sweden)

    Lidia Giuffré

    2007-07-01

    use, to increase population life quality. Social participation in decision of environmental protection aspects must be reinforced. Research processes must be stimulated and sustained, with stimulation of research in university institutions. Information access right is assured; every inhabitant must obtain environmental information from the authorities, if it is not legally considered as reserved information. The most important aspects about environmental education and sustainable development are present as an transversal axis of different jurisdictional application laws, but the enforcement and control of those principles must be assured, considering that environmental laws in Argentina present a low efficacy and efficiency perception.

  5. Development of an optimized algorithm for the characterization of microflow using speckle patterns present in optical coherence tomography signal; Desenvolvimento de um algoritimo otimizado para caracterizacao de fluxos microfluidicos utilizando padroes de speckle presentes no sinal de tomografia por coerencia optica

    Energy Technology Data Exchange (ETDEWEB)

    Pretto, Lucas Ramos de

    2015-07-01

    This work discusses the Optical Coherence Tomography system (OCT) and its application to the microfluidics area. To this end, physical characterization of microfluidic circuits were performed using 3D (three-dimensional) models constructed from OCT images of such circuits. The technique was thus evaluated as a potential tool to aid in the inspection of microchannels. Going further, this work paper studies and develops analytical techniques for microfluidic flow, in particular techniques based on speckle pattern. In the first instance, existing methods were studied and improved, such as Speckle Variance - OCT, where a gain of 31% was obtained in processing time. Other methods, such as LASCA (Laser Speckle Contrast Analysis), based on speckle autocorrelation, are adapted to OCT images. Derived from LASCA, the developed analysis technique based on intensity autocorrelation motivated the development of a custom OCT system as well as an optimized acquisition software, with a sampling rate of 8 kHz. The proposed method was, then, able to distinguish different flow rates, and limits of detection were tested, proving its feasibility for implementation on Brownian motion analysis and flow rates below 10 μl/min. (author)

  6. Past, Present, Future: Developing Linkages Around the Pacific Rim. Proceedings of the Annual Conference of the Pacific Rim Association for Higher Education (3rd, Vancouver, British Columbia, October 12-13, 1982).

    Science.gov (United States)

    Foster, Stephen F., Ed.; Moir, Philip E., Ed.

    Issues facing higher education around the Pacific Rim are considered in 12 conference papers. Titles and authors include the following: "Developing Linkages around the Pacific Rim" (Stephen Foster); "A Cooperative Approach to Professional Development: The Canadian Connection" (Peter Murphy); "Using Film in Teaching…

  7. Tritium practices past and present

    International Nuclear Information System (INIS)

    Gede, V.P.; Gildea, P.D.

    1980-01-01

    History of the production and use of tritium, as well as handling techniques, are reviewed. Handling techniques first used at Lawrence Livermore National Laboratory made use of glass vacuum systems and relatively crude ion chambers for monitoring airborne activity. The first use of inert atmosphere glove boxes demonstrated that uptake through the skin could be a serious personnel exposure problem. Growing environmental concerns in the early 1970's resulted in the implementation by the Atomic Energy Commission of a new criteria to limit atmospheric tritium releases to levels as low as practicable. An important result of the new criteria was the development of containment and recovery systems to capture tritium rather than vent it to the atmosphere. The Sandia National Laboratories, Livermore, Tritium Research Laboratory containment and decontamination systems are presented as a typical example of this technology. The application of computers to control systems is expected to provide the greatest potential for change in future tritium handling practices

  8. Ebolavirus Evolution: Past and Present.

    Directory of Open Access Journals (Sweden)

    Marc-Antoine de La Vega

    Full Text Available The past year has marked the most devastating Ebola outbreak the world has ever witnessed, with over 28,000 cases and over 11,000 deaths. Ebola virus (EBOV has now been around for almost 50 years. In this review, we discuss past and present outbreaks of EBOV and how those variants evolved over time. We explore and discuss selective pressures that drive the evolution of different Ebola variants, and how they may modify the efficacy of therapeutic treatments and vaccines currently being developed. Finally, given the unprecedented size and spread of the outbreak, as well as the extended period of replication in human hosts, specific attention is given to the 2014-2015 West African outbreak variant (Makona.

  9. Development and internal validation of prediction models for biochemical failure and composite failure after focal salvage high intensity focused ultrasound for local radiorecurrent prostate cancer : Presentation of risk scores for individual patient prognoses

    NARCIS (Netherlands)

    Peters, Max; Kanthabalan, Abi; Shah, Taimur T; McCartan, Neil; Moore, Caroline M.; Arya, Manit; van der Voort van Zyp, Jochem R.; Moerland, Marinus A.; Hindley, Richard G.; Emberton, Mark; Ahmed, Hashim U

    2018-01-01

    Purpose Patient selection for focal salvage remains difficult. Therefore, we developed and internally validated prediction models for biochemical failure (BF) and a composite endpoint (CE) following focal salvage high intensity focused ultrasound (HIFU) for radiorecurrent prostate cancer. Materials

  10. Cutaneous sporotrichosis: Unusual clinical presentations

    Directory of Open Access Journals (Sweden)

    Mahajan Vikram

    2010-01-01

    Full Text Available Three unusual clinical forms of sporotrichosis described in this paper will be a primer for the clinicians for an early diagnosis and treatment, especially in its unusual presentations. Case 1, a 52-year-old man, developed sporotrichosis over pre-existing facial nodulo-ulcerative basal cell carcinoma of seven-year duration, due to its contamination perhaps from topical herbal pastes and lymphocutaneous sporotrichosis over right hand/forearm from facial lesion/herbal paste. Case 2, a 25-year-old woman, presented with disseminated systemic-cutaneous, osteoarticular and possibly pleural (effusion sporotrichosis. There was no laboratory evidence of tuberculosis and treatment with anti-tuberculosis drugs (ATT did not benefit. Both these cases were diagnosed by histopathology/culture of S. schenckii from tissue specimens. Case 3, a 20-year-old girl, had multiple intensely pruritic, nodular lesions over/around left knee of two-year duration. She was diagnosed clinically as a case of prurigo nodularis and histologically as cutaneous tuberculosis, albeit, other laboratory investigations and treatment with ATT did not support the diagnosis. All the three patients responded well to saturated solution of potassium iodide (SSKI therapy. A high clinical suspicion is important in early diagnosis and treatment to prevent chronicity and morbidity in these patients. SSKI is fairly safe and effective when itraconazole is not affordable/ available.

  11. Surface Disinfections: Present and Future

    Directory of Open Access Journals (Sweden)

    Matteo Saccucci

    2018-01-01

    Full Text Available The propagation of antibiotic resistance increases the chances of major infections for patients during hospitalization and the spread of health related diseases. Therefore finding new and effective solutions to prevent the proliferation of pathogenic microorganisms is critical, in order to protect hospital environment, such as the surfaces of biomedical devices. Modern nanotechnology has proven to be an effective countermeasure to tackle the threat of infections. On this note, recent scientific breakthroughs have demonstrated that antimicrobial nanomaterials are effective in preventing pathogens from developing resistance. Despite the ability to destroy a great deal of bacteria and control the outbreak of infections, nanomaterials present many other advantages. Moreover, it is unlikely for nanomaterials to develop resistance due to their multiple and simultaneous bactericidal mechanisms. In recent years, science has explored more complex antimicrobial coatings and nanomaterials based on graphene have shown great potential in antibacterial treatment. The purpose of this article is to deepen the discussion on the threat of infections related to surface disinfection and to assess the state of the art and potential solutions, with specific focus on disinfection procedures using nanomaterials.

  12. Euroball. Present status and outlook

    International Nuclear Information System (INIS)

    Simpson, J.

    1997-01-01

    Euroball is a European project to build a highly efficient and powerful gamma-ray spectrometer for nuclear structure spectroscopy. The project is an amalgamation of recent technical advances in detectors, electronics and data acquisition. In the first phase the spectrometer consists of 30 large single crystal Ge detectors, 26 Clover Ge detectors and 15 Cluster Ge detectors each with an associated suppression shield. The 239 individual Ge detector elements will have a total photopeak efficiency ε p of ∼10% and will enable the properties of the atomic nucleus to be studied with a sensitivity up to or better than 10 -5 of the production cross-section. The elements of the spectrometer, including the detectors, the electronics and the data acquisition system, some of the planned ancillary detectors and the first results will be presented. Several developments are under investigation for the upgrade of Euroball for its second phase. These include an inner BGO ball for multiplicity and summed energy determination and inner particle detectors for charged particle identification. These developments will also be discussed. (author)

  13. Predicting the development of traffic fatalities in Latin-American and Carribean countries. Paper presented at the OECD conference on road safety in Latin-American and Carribean countries, Sao Paulo, Brazil, December 1995.

    NARCIS (Netherlands)

    Koornstra, M.J.

    1997-01-01

    Long-term developments in traffic growth and fatality rate can be rather well described by non-linear functions of time. The basics are an S-shaped function for saturating traffic growth (measured by annual motor vehicle kilometres or motorised vehicle volumes) and an exponentially decreasing

  14. Notice presented in the name of the economical affairs, the environment and the territory commission, on the financial law project for 2009 (n. 1127), part 2 ecology, sustainable development and management. volume 1 environment and energy

    International Nuclear Information System (INIS)

    2008-01-01

    This law document concerns the evaluation and analysis of the demanded credits for 2009 (the increase of the credits in the risks prevention, the energy supply in the framework of the climatic change) and the supply of the energy in a context of the environmental quality (the renewable energies development, the electric power production and consumption, the nuclear energy future). (A.L.B.)

  15. Development of a modular lightweight tumour endoprosthesis with novel textile attachment points for the refixation of previously detached muscle groups: Poster presented at 18th EFORT Congress, Sports Activities & Orthopaedic Practice 31 May to 02 June 2017, Vienna

    OpenAIRE

    Grunert, Ronny; Schmidt, Michael; Kopper, Michael; Töppel, Thomas; Rädel, Thomas; Hanus, Sybille; Prietzel, Torsten

    2017-01-01

    Motivation: In tumor endoprosthetics, implants are applied to reconstruct the proximal femur. The main problems of these implants are often the high weight and the biomechanically not optimal attachment of soft tissue. The aim of this work is to solve these problems in order to develop a long-term stable biomechanically correct implant of a proximal femoral replacement. Methods Based on lightweight construction concepts from vehicle construction, a topology optimization was performed with an ...

  16. Presentation of the results 97

    International Nuclear Information System (INIS)

    1998-01-01

    Gaz de France (GDF) presents in a press kit the main results achieved in 1997. The European community has formulated a project of definition of rules concerning the natural gas market. Minima values for annual consumptions have been defined and the consumption and use of natural gas in EC countries is described. The financial results of GDF in 1997 are compared with previous years. Net sales grew by nearly 1 billion french francs to reach 55 billion. Overall sales were down by 4% but the share of natural gas in french energy consumption increased and sales to industrial users went up in particular due to new cogeneration plants installed in 1996. A comparison of gas prices in Europe is given for the years 1985 to 1998. The efforts of GDF to offer increased quality of services concerning in particular safety aspects as checking programs and installation of new safeguard appliances are described. The efforts of GDF to increase the energy market share of natural gas resulted in the development of new products like cogeneration, air conditioning and fuels for automotive needs. (C.B.)

  17. UNSCEAR: present and future activities

    International Nuclear Information System (INIS)

    Holm, Lars-Erik

    2000-01-01

    United Nations Scientific Committee on the Effects of Atomic Radiation (UNSCEAR) was established in 1955. The Committee reviews the exposure of the world population to all sources of radiation under normal circumstances as well as after accidents, and is also the prime international scientific body reviewing and assessing the health risks of exposure to ionizing radiation. Its estimates have been and are still being used by major international bodies including the ICRP, IAEA, and WHO. UNSCEAR's publications form the scientific basis on which international and national agencies develop appropriate radiation protection standards for workers, patients and the general public. UNSCEAR reports yearly to the General Assembly and submits regularly comprehensive reports with detailed scientific annexes on the sources and biological effects of ionizing radiation. In 1995, UNSCEAR began a new program of review of the sources, exposure and biological effects of ionizing radiation. A comprehensive report with scientific annexes will be published in the year 2000. The report will include exposures from natural and man-made radiation sources, occupational and medical radiation exposures, and dose assessment methodologies. The biological effects will cover epidemiological evaluation of radiation-induced cancer, DNA repair and mutagenesis, hereditary effects, combined effects of radiation and other agents, as well as models, mechanisms and uncertainties of biological effects at low radiation doses. An assessment of exposures and effects of the Chernobyl accidents is also made. A brief overview is presented here of the range of subjects considered by the Committee. (author)

  18. Nuclear Fuels: Present and Future

    Directory of Open Access Journals (Sweden)

    Donald R. Olander

    2009-02-01

    Full Text Available The important new developments in nuclear fuels and their problems are reviewed and compared with the status of present light-water reactor fuels. The limitations of these fuels and the reactors they power are reviewed with respect to important recent concerns, namely provision of outlet coolant temperatures high enough for use in H2 production, destruction of plutonium to eliminate proliferation concerns, and burning of the minor actinides to reduce the waste repository heat load and long-term radiation hazard. In addition to current oxide-based fuel-rod designs, the hydride fuel with liquid metal thermal bonding of the fuel-cladding gap is covered. Finally, two of the most promising Generation IV reactor concepts, the Very High Temperature Reactor and the Sodium Fast Reactor, and the accompanying reprocessing technologies, aqueous-based UREX and pyrometallurgical, are summarized. In all of the topics covered, the thermodynamics involved in the material's behavior under irradiation and in the reprocessing schemes are emphasized.

  19. Punch up your podium presentations.

    Science.gov (United States)

    Wood, Tim J; Hollier, Amelie

    2017-08-01

    The goal of most presentations is to engage audience participants. Effective presenters go beyond content expertise to connect with audiences through various techniques, formats, and presentation styles. Mayer's theory of multimedia learning, neurocognitive factors, and the assertion-evidence approach are essential elements that presenters can use if they have not had formal training in creating presentations. Tips are offered on how to connect with the audience and how to avoid known pitfalls. ©2017 American Association of Nurse Practitioners.

  20. Put Power into Your Presentations: Using Presentation Software Effectively

    Science.gov (United States)

    Safransky, Robert J.; Burmeister, Marsha L.

    2009-01-01

    Microsoft PowerPoint, Apple Keynote, and OpenOffice Impress are relatively common tools in the classroom and in the boardroom these days. What makes presentation software so popular? As the Chinese proverb declares, a picture is worth a thousand words. People like visual presentations. Presentation software can make even a dull subject come to…