WorldWideScience

Sample records for three-dimensional relativistic particle-in-cell

  1. Relativistic three-particle dynamical equations: I. Theoretical development

    International Nuclear Information System (INIS)

    Adhikari, S.K.; Tomio, L.; Frederico, T.

    1993-11-01

    Starting from the two-particle Bethe-Salpeter equation in the ladder approximation and integrating over the time component of momentum, three dimensional scattering integral equations satisfying constrains of relativistic unitarity and covariance are rederived. These equations were first derived by Weinberg and by Blankenbecler and Sugar. These two-particle equations are shown to be related by a transformation of variables. Hence it is shown to perform and relate dynamical calculation using these two equations. Similarly, starting from the Bethe-Salpeter-Faddeev equation for the three-particle system and integrating over the time component of momentum, several three dimensional three-particle scattering equations satisfying constraints of relativistic unitary and covariance are derived. Two of these three-particle equations are related by a transformation of variables as in the two-particle case. The three-particle equations obtained are very practical and suitable for performing relativistic scattering calculations. (author)

  2. Investigation of Rising-Sun Magnetrons Operated at Relativistic Voltages Using Three Dimensional Particle-in-Cell Simulation

    International Nuclear Information System (INIS)

    Lemke, R.W.; Genoni, T.C.; Spencer, T.A.

    1999-01-01

    This work is an attempt to elucidate effects that may limit efficiency in magnetrons operated at relativistic voltages (V ∼ 500 kV). Three-dimensional particle-in-cell simulation is used to investigate the behavior of 14 and 22 cavity, cylindrical, rising-sun magnetrons. Power is extracted radially through a single iris located at the end of every other cavity. Numerical results show that in general output power and efficiency increase approximately linearly with increasing iris width (decreasing vacuum Q) until the total Q becomes too low for stable oscillation in the n-mode to be maintained. Beyond this point mode competition and/or switching occur and efficiency decreases. Results reveal that the minimum value of Q (maximum efficiency) that can be achieved prior to the onset of mode competition is significantly affected by the magnitude of the 0-space-harmonic of the π-mode, a unique characteristic of rising-suns, and by the magnitude of the electron current density (space-charge effects). By minimizing these effects, up to 3.7 GW output power has been produced at an efficiency of 40%

  3. Relativistic formulations with Blankenbecler-Sugar reduction technique for the three-particle system

    International Nuclear Information System (INIS)

    Morioka, S.; Afnan, I.R.

    1980-05-01

    A critical comparison for two-types of three-dimensional covariant equations for the three-particle system obtained by the Blankenbecler-Sugar reduction technique with the Whitghtman-Garding momenta and the usual Jacobi variables is presented. The relations between the relativistic and non-relativistic equations in the low energy limit are discussed

  4. Relativistic three-particle theory

    International Nuclear Information System (INIS)

    Hochauser, S.

    1979-01-01

    In keeping with recent developments in experimental nuclear physics, a formalism is developed to treat interactions between three relativistic nuclear particles. The concept of unitarity and a simple form of analyticity are used to construct coupled, integral, Faddeev-type equations and, with the help of analytic separable potentials, these are cast in simple, one-dimensional form. Energy-dependent potentials are introduced so as to take into account the sign-change of some phase shifts in the nucleon-nucleon interaction and parameters for these potentials are obtained. With regard to the success of such local potentials as the Yukawa potential, a recently developed method for expanding these in separable form is discussed. Finally, a new method for the numerical integration of the Faddeev equations along the real axis is introduced, thus avoiding the traditional need for contour rotations into the complex plane. (author)

  5. Three-dimensional lagrangian approach to the classical relativistic dynamics of directly interacting particles

    International Nuclear Information System (INIS)

    Gaida, R.P.; Kluchkousky, Ya.B.; Tretyak, V.I.

    1987-01-01

    In the present report the main attention is paid to the interrelations of various three-dimensional approaches and to the relation of the latter to the Fokker-type action formalism; the problem of the correspondence between three-dimensional descriptions and singular Lagrangian formalism will be shortly concerned. The authors start with the three-dimensional Lagrangian formulation of the classical RDIT. The generality of this formalism enables, similarly as in the non-relativistic case, to consider it as a central link explaining naturally a number of features of other three-dimensional approaches, namely Newtonian (based directly on second order equations of motion) and Hamiltonian ones). It is also capable of describing four-dimensional manifestly covariant models using Fokker action integrals and singular Lagrangians

  6. Relativistic particle in a box

    OpenAIRE

    Alberto, P.; Fiolhais, Carlos; Gil, Victor

    1996-01-01

    The problem of a relativistic spin 1/2 particle confined to a one-dimensional box is solved in a way that resembles closely the solution of the well known quantum-mechanical textbook problem of a non-relativistic particle in a box. The energy levels and probability density are computed and compared with the non-relativistic case

  7. Particle-in-cell simulation of two-dimensional electron velocity shear driven instability in relativistic domain

    Energy Technology Data Exchange (ETDEWEB)

    Shukla, Chandrasekhar, E-mail: chandrasekhar.shukla@gmail.com; Das, Amita, E-mail: amita@ipr.res.in [Institute for Plasma Research, Bhat, Gandhinagar 382428 (India); Patel, Kartik [Bhabha Atomic Research Centre, Trombay, Mumbai 400 085 (India)

    2016-08-15

    We carry out particle-in-cell simulations to study the instabilities associated with a 2-D sheared electron flow configuration against a neutralizing background of ions. Both weak and strong relativistic flow velocities are considered. In the weakly relativistic case, we observe the development of electromagnetic Kelvin-Helmholtz instability with similar characteristics as that predicted by the electron Magnetohydrodynamic (EMHD) model. On the contrary, in a strong relativistic case, the compressibility effects of electron fluid dominate and introduce upper hybrid electrostatic oscillations transverse to the flow which are very distinct from EMHD fluid behavior. In the nonlinear regime, both weak and strong relativistic cases lead to turbulence with broad power law spectrum.

  8. Delocalization of Relativistic Dirac Particles in Disordered One-Dimensional Systems and Its Implementation with Cold Atoms

    International Nuclear Information System (INIS)

    Zhu Shiliang; Zhang Danwei; Wang, Z. D.

    2009-01-01

    We study theoretically the localization of relativistic particles in disordered one-dimensional chains. It is found that the relativistic particles tend to delocalization in comparison with the nonrelativistic particles with the same disorder strength. More intriguingly, we reveal that the massless Dirac particles are entirely delocalized for any energy due to the inherent chiral symmetry, leading to a well-known result that particles are always localized in one-dimensional systems for arbitrary weak disorders to break down. Furthermore, we propose a feasible scheme to detect the delocalization feature of the Dirac particles with cold atoms in a light-induced gauge field.

  9. Enhanced stopping of macro-particles in particle-in-cell simulations

    International Nuclear Information System (INIS)

    May, J.; Tonge, J.; Ellis, I.; Mori, W. B.; Fiuza, F.; Fonseca, R. A.; Silva, L. O.; Ren, C.

    2014-01-01

    We derive an equation for energy transfer from relativistic charged particles to a cold background plasma appropriate for finite-size particles that are used in particle-in-cell simulation codes. Expressions for one-, two-, and three-dimensional particles are presented, with special attention given to the two-dimensional case. This energy transfer is due to the electric field of the wake set up in the background plasma by the relativistic particle. The enhanced stopping is dependent on the q 2 /m, where q is the charge and m is the mass of the relativistic particle, and therefore simulation macro-particles with large charge but identical q/m will stop more rapidly. The stopping power also depends on the effective particle shape of the macro-particle. These conclusions are verified in particle-in-cell simulations. We present 2D simulations of test particles, relaxation of high-energy tails, and integrated fast ignition simulations showing that the enhanced drag on macro-particles may adversely affect the results of these simulations in a wide range of high-energy density plasma scenarios. We also describe a particle splitting algorithm which can potentially overcome this problem and show its effect in controlling the stopping of macro-particles

  10. Three-dimensional relativistic pair plasma reconnection with radiative feedback in the Crab Nebula

    Energy Technology Data Exchange (ETDEWEB)

    Cerutti, B. [Department of Astrophysical Sciences, Princeton University, Princeton, NJ 08544 (United States); Werner, G. R.; Uzdensky, D. A. [Center for Integrated Plasma Studies, Physics Department, University of Colorado, UCB 390, Boulder, CO 80309-0390 (United States); Begelman, M. C., E-mail: bcerutti@astro.princeton.edu, E-mail: greg.werner@colorado.edu, E-mail: uzdensky@colorado.edu, E-mail: mitch@jila.colorado.edu [JILA, University of Colorado and National Institute of Standards and Technology, UCB 440, Boulder, CO 80309-0440 (United States)

    2014-02-20

    The discovery of rapid synchrotron gamma-ray flares above 100 MeV from the Crab Nebula has attracted new interest in alternative particle acceleration mechanisms in pulsar wind nebulae. Diffuse shock-acceleration fails to explain the flares because particle acceleration and emission occur during a single or even sub-Larmor timescale. In this regime, the synchrotron energy losses induce a drag force on the particle motion that balances the electric acceleration and prevents the emission of synchrotron radiation above 160 MeV. Previous analytical studies and two-dimensional (2D) particle-in-cell (PIC) simulations indicate that relativistic reconnection is a viable mechanism to circumvent the above difficulties. The reconnection electric field localized at X-points linearly accelerates particles with little radiative energy losses. In this paper, we check whether this mechanism survives in three dimension (3D), using a set of large PIC simulations with radiation reaction force and with a guide field. In agreement with earlier works, we find that the relativistic drift kink instability deforms and then disrupts the layer, resulting in significant plasma heating but few non-thermal particles. A moderate guide field stabilizes the layer and enables particle acceleration. We report that 3D magnetic reconnection can accelerate particles above the standard radiation reaction limit, although the effect is less pronounced than in 2D with no guide field. We confirm that the highest-energy particles form compact bunches within magnetic flux ropes, and a beam tightly confined within the reconnection layer, which could result in the observed Crab flares when, by chance, the beam crosses our line of sight.

  11. Relativistic particle in a box: Klein-Gordon versus Dirac equations

    Science.gov (United States)

    Alberto, Pedro; Das, Saurya; Vagenas, Elias C.

    2018-03-01

    The problem of a particle in a box is probably the simplest problem in quantum mechanics which allows for significant insight into the nature of quantum systems and thus is a cornerstone in the teaching of quantum mechanics. In relativistic quantum mechanics this problem allows also to highlight the implications of special relativity for quantum physics, namely the effect that spin has on the quantised energy spectra. To illustrate this point, we solve the problem of a spin zero relativistic particle in a one- and three-dimensional box using the Klein-Gordon equation in the Feshbach-Villars formalism. We compare the solutions and the energy spectra obtained with the corresponding ones from the Dirac equation for a spin one-half relativistic particle. We note the similarities and differences, in particular the spin effects in the relativistic energy spectrum. As expected, the non-relativistic limit is the same for both kinds of particles, since, for a particle in a box, the spin contribution to the energy is a relativistic effect.

  12. Relativistic three-particle dynamical equations: II. Application to the trinucleon system

    International Nuclear Information System (INIS)

    Adhikari, S.K.; Tomio, L.

    1993-11-01

    The contribution of relativistic dynamics on the neutron-deuteron scattering length and triton binding energy is calculated employing five sets tri nucleon potential models and four types of three-dimensional relativistic three-body equations suggested in the preceding paper. The relativistic correction to binding energy may vary a lot and even change sign depending on the relativistic formulation employed. The deviations of these observables from those obtained in nonrelativistic models follow the general universal trend of deviations introduced by off- and on-shell variations of two- and three-nucleon potentials in a nonrelativistic model calculation. Consequently, it will be difficult to separate unambiguously the effect of off-and on-shell variations of two and three-nucleon potentials on low-energy three-nucleon observables from the effect of relativistic dynamics. (author)

  13. A Comprehensive Comparison of Relativistic Particle Integrators

    Science.gov (United States)

    Ripperda, B.; Bacchini, F.; Teunissen, J.; Xia, C.; Porth, O.; Sironi, L.; Lapenta, G.; Keppens, R.

    2018-03-01

    We compare relativistic particle integrators commonly used in plasma physics, showing several test cases relevant for astrophysics. Three explicit particle pushers are considered, namely, the Boris, Vay, and Higuera–Cary schemes. We also present a new relativistic fully implicit particle integrator that is energy conserving. Furthermore, a method based on the relativistic guiding center approximation is included. The algorithms are described such that they can be readily implemented in magnetohydrodynamics codes or Particle-in-Cell codes. Our comparison focuses on the strengths and key features of the particle integrators. We test the conservation of invariants of motion and the accuracy of particle drift dynamics in highly relativistic, mildly relativistic, and non-relativistic settings. The methods are compared in idealized test cases, i.e., without considering feedback onto the electrodynamic fields, collisions, pair creation, or radiation. The test cases include uniform electric and magnetic fields, {\\boldsymbol{E}}× {\\boldsymbol{B}} fields, force-free fields, and setups relevant for high-energy astrophysics, e.g., a magnetic mirror, a magnetic dipole, and a magnetic null. These tests have direct relevance for particle acceleration in shocks and in magnetic reconnection.

  14. Evolution of three-dimensional relativistic current sheets and development of self-generated turbulence

    Science.gov (United States)

    Takamoto, M.

    2018-05-01

    In this paper, the temporal evolution of three-dimensional relativistic current sheets in Poynting-dominated plasma is studied for the first time. Over the past few decades, a lot of efforts have been conducted on studying the evolution of current sheets in two-dimensional space, and concluded that sufficiently long current sheets always evolve into the so-called plasmoid chain, which provides a fast reconnection rate independent of its resistivity. However, it is suspected that plasmoid chain can exist only in the case of two-dimensional approximation, and would show transition to turbulence in three-dimensional space. We performed three-dimensional numerical simulation of relativistic current sheet using resistive relativistic magnetohydrodynamic approximation. The results showed that the three-dimensional current sheets evolve not into plasmoid chain but turbulence. The resulting reconnection rate is 0.004, which is much smaller than that of plasmoid chain. The energy conversion from magnetic field to kinetic energy of turbulence is just 0.01 per cent, which is much smaller than typical non-relativistic cases. Using the energy principle, we also showed that the plasmoid is always unstable for a displacement in the opposite direction to its acceleration, probably interchange-type instability, and this always results in seeds of turbulence behind the plasmoids. Finally, the temperature distribution along the sheet is discussed, and it is found that the sheet is less active than plasmoid chain. Our finding can be applied for many high-energy astrophysical phenomena, and can provide a basic model of the general current sheet in Poynting-dominated plasma.

  15. LPIC++. A parallel one-dimensional relativistic electromagnetic particle-in-cell code for simulating laser-plasma-interaction

    International Nuclear Information System (INIS)

    Lichters, R.; Pfund, R.E.W.; Meyer-ter-Vehn, J.

    1997-08-01

    The code LPIC++ presented here, is based on a one-dimensional, electromagnetic, relativistic PIC code that has originally been developed by one of the authors during a PhD thesis at the Max-Planck-Institut fuer Quantenoptik for kinetic simulations of high harmonic generation from overdense plasma surfaces. The code uses essentially the algorithm of Birdsall and Langdon and Villasenor and Bunemann. It is written in C++ in order to be easily extendable and has been parallelized to be able to grow in power linearly with the size of accessable hardware, e.g. massively parallel machines like Cray T3E. The parallel LPIC++ version uses PVM for communication between processors. PVM is public domain software, can be downloaded from the world wide web. A particular strength of LPIC++ lies in its clear program and data structure, which uses chained lists for the organization of grid cells and enables dynamic adjustment of spatial domain sizes in a very convenient way, and therefore easy balancing of processor loads. Also particles belonging to one cell are linked in a chained list and are immediately accessable from this cell. In addition to this convenient type of data organization in a PIC code, the code shows excellent performance in both its single processor and parallel version. (orig.)

  16. Relativistic three-dimensional Lippmann-Schwinger cross sections for space radiation applications

    Science.gov (United States)

    Werneth, C. M.; Xu, X.; Norman, R. B.; Maung, K. M.

    2017-12-01

    Radiation transport codes require accurate nuclear cross sections to compute particle fluences inside shielding materials. The Tripathi semi-empirical reaction cross section, which includes over 60 parameters tuned to nucleon-nucleus (NA) and nucleus-nucleus (AA) data, has been used in many of the world's best-known transport codes. Although this parameterization fits well to reaction cross section data, the predictive capability of any parameterization is questionable when it is used beyond the range of the data to which it was tuned. Using uncertainty analysis, it is shown that a relativistic three-dimensional Lippmann-Schwinger (LS3D) equation model based on Multiple Scattering Theory (MST) that uses 5 parameterizations-3 fundamental parameterizations to nucleon-nucleon (NN) data and 2 nuclear charge density parameterizations-predicts NA and AA reaction cross sections as well as the Tripathi cross section parameterization for reactions in which the kinetic energy of the projectile in the laboratory frame (TLab) is greater than 220 MeV/n. The relativistic LS3D model has the additional advantage of being able to predict highly accurate total and elastic cross sections. Consequently, it is recommended that the relativistic LS3D model be used for space radiation applications in which TLab > 220MeV /n .

  17. Relativistic collective diffusion in one-dimensional systems

    Science.gov (United States)

    Lin, Gui-Wu; Lam, Yu-Yiu; Zheng, Dong-Qin; Zhong, Wei-Rong

    2018-05-01

    The relativistic collective diffusion in one-dimensional molecular system is investigated through nonequilibrium molecular dynamics with Monte Carlo methods. We have proposed the relationship among the speed, the temperature, the density distribution and the collective diffusion coefficient of particles in a relativistic moving system. It is found that the relativistic speed of the system has no effect on the temperature, but the collective diffusion coefficient decreases to zero as the velocity of the system approaches to the speed of light. The collective diffusion coefficient is modified as D‧ = D(1 ‑w2 c2 )3 2 for satisfying the relativistic circumstances. The present results may contribute to the understanding of the behavior of the particles transport diffusion in a high speed system, as well as enlighten the study of biological metabolism at relativistic high speed situation.

  18. SHARP: A Spatially Higher-order, Relativistic Particle-in-cell Code

    Energy Technology Data Exchange (ETDEWEB)

    Shalaby, Mohamad; Broderick, Avery E. [Department of Physics and Astronomy, University of Waterloo, 200 University Avenue West, Waterloo, ON, N2L 3G1 (Canada); Chang, Philip [Department of Physics, University of Wisconsin-Milwaukee, 1900 E. Kenwood Boulevard, Milwaukee, WI 53211 (United States); Pfrommer, Christoph [Leibniz-Institut für Astrophysik Potsdam (AIP), An der Sternwarte 16, D-14482 Potsdam (Germany); Lamberts, Astrid [Theoretical Astrophysics, California Institute of Technology, Pasadena, CA 91125 (United States); Puchwein, Ewald, E-mail: mshalaby@live.ca [Institute of Astronomy and Kavli Institute for Cosmology, University of Cambridge, Madingley Road, Cambridge, CB3 0HA (United Kingdom)

    2017-05-20

    Numerical heating in particle-in-cell (PIC) codes currently precludes the accurate simulation of cold, relativistic plasma over long periods, severely limiting their applications in astrophysical environments. We present a spatially higher-order accurate relativistic PIC algorithm in one spatial dimension, which conserves charge and momentum exactly. We utilize the smoothness implied by the usage of higher-order interpolation functions to achieve a spatially higher-order accurate algorithm (up to the fifth order). We validate our algorithm against several test problems—thermal stability of stationary plasma, stability of linear plasma waves, and two-stream instability in the relativistic and non-relativistic regimes. Comparing our simulations to exact solutions of the dispersion relations, we demonstrate that SHARP can quantitatively reproduce important kinetic features of the linear regime. Our simulations have a superior ability to control energy non-conservation and avoid numerical heating in comparison to common second-order schemes. We provide a natural definition for convergence of a general PIC algorithm: the complement of physical modes captured by the simulation, i.e., those that lie above the Poisson noise, must grow commensurately with the resolution. This implies that it is necessary to simultaneously increase the number of particles per cell and decrease the cell size. We demonstrate that traditional ways for testing for convergence fail, leading to plateauing of the energy error. This new PIC code enables us to faithfully study the long-term evolution of plasma problems that require absolute control of the energy and momentum conservation.

  19. Three-dimensional formulation of the relativistic two-body problem in terms of rapidities

    International Nuclear Information System (INIS)

    Amirkhanov, I.V.; Grusha, G.V.; Mir-Kasimov, R.M.

    1976-01-01

    The scheme, based on the three-dimensional relativistic equation of the quasi-potential type is developed. As a basic variable rapidity, canonically conjugated to the relativistic relative distance is adopted. The free Green function has a simple pole in the complex rapidity plane, ensuring the fulfillment of the elastic unitarity for real potentials. In the local potential case the corresponding partial wave equation in configurational r-representation is a differential second-order equation. The problem of boundary conditions, which is a non-trivial one in the relativistic r-space, is studied. The exact solutions of the equation in simple cases have been found

  20. Three-dimensional labeling program for elucidation of the geometric properties of biological particles in three-dimensional space.

    Science.gov (United States)

    Nomura, A; Yamazaki, Y; Tsuji, T; Kawasaki, Y; Tanaka, S

    1996-09-15

    For all biological particles such as cells or cellular organelles, there are three-dimensional coordinates representing the centroid or center of gravity. These coordinates and other numerical parameters such as volume, fluorescence intensity, surface area, and shape are referred to in this paper as geometric properties, which may provide critical information for the clarification of in situ mechanisms of molecular and cellular functions in living organisms. We have established a method for the elucidation of these properties, designated the three-dimensional labeling program (3DLP). Algorithms of 3DLP are so simple that this method can be carried out through the use of software combinations in image analysis on a personal computer. To evaluate 3DLP, it was applied to a 32-cell-stage sea urchin embryo, double stained with FITC for cellular protein of blastomeres and propidium iodide for nuclear DNA. A stack of optical serial section images was obtained by confocal laser scanning microscopy. The method was found effective for determining geometric properties and should prove applicable to the study of many different kinds of biological particles in three-dimensional space.

  1. Form factor of relativistic two-particle system and covariant hamiltonian formulation of quantum field theory

    International Nuclear Information System (INIS)

    Skachkov, N.; Solovtsov, I.

    1979-01-01

    Based on the hamiltonian formulation of quantum field theory proposed by Kadyshevsky the three-dimensional relativistic approach is developed for describing the form factors of composite systems. The main features of the diagram technique appearing in the covariant hamiltonian formulation of field theory are discussed. The three-dimensional relativistic equation for the vertex function is derived and its connection with that for the quasipotential wave function is found. The expressions are obtained for the form factor of the system through equal-time two-particle wave functions both in momentum and relativistic configurational representations. An explicit expression for the form factor is found for the case of two-particle interaction through the Coulomb potential

  2. Loading relativistic Maxwell distributions in particle simulations

    Energy Technology Data Exchange (ETDEWEB)

    Zenitani, Seiji, E-mail: seiji.zenitani@nao.ac.jp [National Astronomical Observatory of Japan, 2-21-1 Osawa, Mitaka, Tokyo 181-8588 (Japan)

    2015-04-15

    Numerical algorithms to load relativistic Maxwell distributions in particle-in-cell (PIC) and Monte-Carlo simulations are presented. For stationary relativistic Maxwellian, the inverse transform method and the Sobol algorithm are reviewed. To boost particles to obtain relativistic shifted-Maxwellian, two rejection methods are proposed in a physically transparent manner. Their acceptance efficiencies are ≈50% for generic cases and 100% for symmetric distributions. They can be combined with arbitrary base algorithms.

  3. Loading relativistic Maxwell distributions in particle simulations

    International Nuclear Information System (INIS)

    Zenitani, Seiji

    2015-01-01

    Numerical algorithms to load relativistic Maxwell distributions in particle-in-cell (PIC) and Monte-Carlo simulations are presented. For stationary relativistic Maxwellian, the inverse transform method and the Sobol algorithm are reviewed. To boost particles to obtain relativistic shifted-Maxwellian, two rejection methods are proposed in a physically transparent manner. Their acceptance efficiencies are ≈50% for generic cases and 100% for symmetric distributions. They can be combined with arbitrary base algorithms

  4. Relativistic scattering theory of charged spinless particles

    International Nuclear Information System (INIS)

    Alt, E.O.; Hannemann, M.

    1986-01-01

    In the context of relativistic quantum mechanics the scattering is discussed of two and three charged spinless particles. The corresponding transition operators are shown to satisfy four-dimensional Lippmann-Schwinger and eight-dimensional Faddeev-type equations, respectively. A simplified model of two particles with Coulomb interaction can be solved exactly. Calculations have been made of (i) the partial wave S-matrix from which the bound state spectrum has been extracted; the latter agrees with a fourth-order result of Schwinger; (ii) the full scattering amplitude which in the weak-field limit coincides with the expression derived by Fried et al. from eikonalized QED. (author)

  5. A three-dimensional electrostatic particle-in-cell methodology on unstructured Delaunay-Voronoi grids

    International Nuclear Information System (INIS)

    Gatsonis, Nikolaos A.; Spirkin, Anton

    2009-01-01

    The mathematical formulation and computational implementation of a three-dimensional particle-in-cell methodology on unstructured Delaunay-Voronoi tetrahedral grids is presented. The method allows simulation of plasmas in complex domains and incorporates the duality of the Delaunay-Voronoi in all aspects of the particle-in-cell cycle. Charge assignment and field interpolation weighting schemes of zero- and first-order are formulated based on the theory of long-range constraints. Electric potential and fields are derived from a finite-volume formulation of Gauss' law using the Voronoi-Delaunay dual. Boundary conditions and the algorithms for injection, particle loading, particle motion, and particle tracking are implemented for unstructured Delaunay grids. Error and sensitivity analysis examines the effects of particles/cell, grid scaling, and timestep on the numerical heating, the slowing-down time, and the deflection times. The problem of current collection by cylindrical Langmuir probes in collisionless plasmas is used for validation. Numerical results compare favorably with previous numerical and analytical solutions for a wide range of probe radius to Debye length ratios, probe potentials, and electron to ion temperature ratios. The versatility of the methodology is demonstrated with the simulation of a complex plasma microsensor, a directional micro-retarding potential analyzer that includes a low transparency micro-grid.

  6. Loading relativistic Maxwell distributions in particle simulations

    Science.gov (United States)

    Zenitani, S.

    2015-12-01

    In order to study energetic plasma phenomena by using particle-in-cell (PIC) and Monte-Carlo simulations, we need to deal with relativistic velocity distributions in these simulations. However, numerical algorithms to deal with relativistic distributions are not well known. In this contribution, we overview basic algorithms to load relativistic Maxwell distributions in PIC and Monte-Carlo simulations. For stationary relativistic Maxwellian, the inverse transform method and the Sobol algorithm are reviewed. To boost particles to obtain relativistic shifted-Maxwellian, two rejection methods are newly proposed in a physically transparent manner. Their acceptance efficiencies are 􏰅50% for generic cases and 100% for symmetric distributions. They can be combined with arbitrary base algorithms.

  7. Relativistic laser channeling in plasmas for fast ignition

    Science.gov (United States)

    Lei, A. L.; Pukhov, A.; Kodama, R.; Yabuuchi, T.; Adumi, K.; Endo, K.; Freeman, R. R.; Habara, H.; Kitagawa, Y.; Kondo, K.; Kumar, G. R.; Matsuoka, T.; Mima, K.; Nagatomo, H.; Norimatsu, T.; Shorokhov, O.; Snavely, R.; Yang, X. Q.; Zheng, J.; Tanaka, K. A.

    2007-12-01

    We report an experimental observation suggesting plasma channel formation by focusing a relativistic laser pulse into a long-scale-length preformed plasma. The channel direction coincides with the laser axis. Laser light transmittance measurement indicates laser channeling into the high-density plasma with relativistic self-focusing. A three-dimensional particle-in-cell simulation reproduces the plasma channel and reveals that the collimated hot-electron beam is generated along the laser axis in the laser channeling. These findings hold the promising possibility of fast heating a dense fuel plasma with a relativistic laser pulse.

  8. ELECTRON ACCELERATIONS AT HIGH MACH NUMBER SHOCKS: TWO-DIMENSIONAL PARTICLE-IN-CELL SIMULATIONS IN VARIOUS PARAMETER REGIMES

    Energy Technology Data Exchange (ETDEWEB)

    Matsumoto, Yosuke [Department of Physics, Chiba University, Yayoi-cho 1-33, Inage-ku, Chiba 263-8522 (Japan); Amano, Takanobu; Hoshino, Masahiro, E-mail: ymatumot@astro.s.chiba-u.ac.jp [Department of Earth and Planetary Science, University of Tokyo, Hongo 1-33, Bunkyo-ku, Tokyo 113-0033 (Japan)

    2012-08-20

    Electron accelerations at high Mach number collisionless shocks are investigated by means of two-dimensional electromagnetic particle-in-cell simulations with various Alfven Mach numbers, ion-to-electron mass ratios, and the upstream electron {beta}{sub e} (the ratio of the thermal pressure to the magnetic pressure). We find electrons are effectively accelerated at a super-high Mach number shock (M{sub A} {approx} 30) with a mass ratio of M/m = 100 and {beta}{sub e} = 0.5. The electron shock surfing acceleration is an effective mechanism for accelerating the particles toward the relativistic regime even in two dimensions with a large mass ratio. Buneman instability excited at the leading edge of the foot in the super-high Mach number shock results in a coherent electrostatic potential structure. While multi-dimensionality allows the electrons to escape from the trapping region, they can interact with the strong electrostatic field several times. Simulation runs in various parameter regimes indicate that the electron shock surfing acceleration is an effective mechanism for producing relativistic particles in extremely high Mach number shocks in supernova remnants, provided that the upstream electron temperature is reasonably low.

  9. Five-dimensional Hamiltonian-Jacobi approach to relativistic quantum mechanics

    International Nuclear Information System (INIS)

    Rose, Harald

    2003-01-01

    A novel theory is outlined for describing the dynamics of relativistic electrons and positrons. By introducing the Lorentz-invariant universal time as a fifth independent variable, the Hamilton-Jacobi formalism of classical mechanics is extended from three to four spatial dimensions. This approach allows one to incorporate gravitation and spin interactions in the extended five-dimensional Lagrangian in a covariant form. The universal time has the function of a hidden Bell parameter. By employing the method of variation with respect to the four coordinates of the particle and the components of the electromagnetic field, the path equation and the electromagnetic field produced by the charge and the spin of the moving particle are derived. In addition the covariant equations for the dynamics of the components of the spin tensor are obtained. These equations can be transformed to the familiar BMT equation in the case of homogeneous electromagnetic fields. The quantization of the five-dimensional Hamilton-Jacobi equation yields a five-dimensional spinor wave equation, which degenerates to the Dirac equation in the stationary case if we neglect gravitation. The quantity which corresponds to the probability density of standard quantum mechanics is the four-dimensional mass density which has a real physical meaning. By means of the Green method the wave equation is transformed into an integral equation enabling a covariant relativistic path integral formulation. Using this approach a very accurate approximation for the four-dimensional propagator is derived. The proposed formalism makes Dirac's hole theory obsolete and can readily be extended to many particles

  10. Physics of the saturation of particle acceleration in relativistic magnetic reconnection

    Science.gov (United States)

    Kagan, Daniel; Nakar, Ehud; Piran, Tsvi

    2018-05-01

    We investigate the saturation of particle acceleration in relativistic reconnection using two-dimensional particle-in-cell simulations at various magnetizations σ. We find that the particle energy spectrum produced in reconnection quickly saturates as a hard power law that cuts off at γ ≈ 4σ, confirming previous work. Using particle tracing, we find that particle acceleration by the reconnection electric field in X-points determines the shape of the particle energy spectrum. By analysing the current sheet structure, we show that physical cause of saturation is the spontaneous formation of secondary magnetic islands that can disrupt particle acceleration. By comparing the size of acceleration regions to the typical distance between disruptive islands, we show that the maximum Lorentz factor produced in reconnection is γ ≈ 5σ, which is very close to what we find in our particle energy spectra. We also show that the dynamic range in Lorentz factor of the power-law spectrum in reconnection is ≤40. The hardness of the power law combined with its narrow dynamic range implies that relativistic reconnection is capable of producing the hard narrow-band flares observed in the Crab nebula but has difficulty producing the softer broad-band prompt gamma-ray burst emission.

  11. Relativistic ''potential model'' for N-particle systems

    International Nuclear Information System (INIS)

    Noyes, H.P.

    1986-08-01

    Neither quantum field theory nor S-Matrix theory have a well defined procedure for going over to an approximation that can be reliably used in non-relativistic models for nuclear physics. We meet the problem here by constructing a finite particle number relativistic scattering theory for (scalar) particles and mesons using integral equations of the Faddeev-Yakubovsky type. Restricted to N particles and one meson, we can go from the relativistic theory to a ''potential theory'' in the integral equation formulation by using boundary states which do not contain the meson asymptotically. The meson-particle input amplitudes contain a pole at the particle mass, and the particle-particle input amplitudes are null. This gives unique definition (numerically calculable) to the particle-particle off-shell amplitude, and hence to the covariant ''scattering potential'' (but not to the noninvariant concept of ''potential energy''). As we have commented before, if we take these scattering amplitudes as iput for relativistic Faddeev equations, the results are identical to those obtained from the same model starting from three particles and one meson. In this paper we explore how far we can extend this relativistic ''potential model'' to higher numbers of particles and mesons. 10 refs

  12. Two-dimensional ion effects in relativistic diodes

    International Nuclear Information System (INIS)

    Poukey, J.W.

    1975-01-01

    In relativistic diodes, ions are emitted from the anode plasma. The effects and properties of these ions are studied via a two-dimensional particle simulation code. The space charge of these ions enhances the electron emission, and this additional current (including that of the ions, themselves) aids in obtaining superpinched electron beams for use in pellet fusion studies. (U.S.)

  13. Scattering in relativistic particle mechanics

    International Nuclear Information System (INIS)

    De Bievre, S.

    1986-01-01

    The problem of direct interaction in relativistic particle mechanics has been extensively studied and a variety of models has been proposed avoiding the conclusions of the so-called no-interaction theorems. In this thesis the authors studied scattering in the relativistic two-body problem. He uses the results to analyze gauge invariance in Hamiltonian constraint models and the uniqueness of the symplectic structure in manifestly covariant relativistic particle mechanics. A general geometric framework that underlies approaches to relativistic particle mechanics is presented and the kinematic properties of the scattering transformation, i.e., those properties that arise solely from the invariance of the theory under the Poincare group are studied. The second part of the analysis of the relativistic two-body scattering problem is devoted to the dynamical properties of the scattering process. Using general geometric arguments, gauge invariance of the scattering transformation in the Todorov-Komar Hamiltonian constraint model is proved. Finally, quantization of the models is discussed

  14. Excitation of atomic nuclei and atoms by relativistic charge particles bound in a one-dimensional potential

    International Nuclear Information System (INIS)

    Almaliev, A.N.; Batkin, I.S.; Kopytin, I.V.

    1987-01-01

    The process of exciting atoms and atomic nuclei by relativistic electrons and positrons bound in a one-dimensional potential is investigated theoretically. It is shown that a pole corresponding to the emergence of a virtual photon on a bulk surface occurs in the matrix interaction element under definite kinematic relationships. It is obtained that the probability of the excitation process depends on the lifetime of the level being excited, the virtual photon, and the charged particle in a definite energetic state. An estimate of the magnitude of the excitation section of low-lying nuclear states yields a value exceeding by several orders the section obtained for charged particles in the absence of a binding potential

  15. High energy gain in three-dimensional simulations of light sail acceleration

    Energy Technology Data Exchange (ETDEWEB)

    Sgattoni, A., E-mail: andrea.sgattoni@polimi.it [Dipartimento di Energia, Politecnico di Milano, Milano (Italy); CNR, Istituto Nazionale di Ottica, u.o.s. “Adriano Gozzini,” Pisa (Italy); Sinigardi, S. [CNR, Istituto Nazionale di Ottica, u.o.s. “Adriano Gozzini,” Pisa (Italy); Dipartimento di Fisica e Astronomia, Università di Bologna, Bologna (Italy); INFN sezione di Bologna, Bologna (Italy); Macchi, A. [CNR, Istituto Nazionale di Ottica, u.o.s. “Adriano Gozzini,” Pisa (Italy); Dipartimento di Fisica “Enrico Fermi,” Università di Pisa, Pisa (Italy)

    2014-08-25

    The dynamics of radiation pressure acceleration in the relativistic light sail regime are analysed by means of large scale, three-dimensional (3D) particle-in-cell simulations. Differently to other mechanisms, the 3D dynamics leads to faster and higher energy gain than in 1D or 2D geometry. This effect is caused by the local decrease of the target density due to transverse expansion leading to a “lighter sail.” However, the rarefaction of the target leads to an earlier transition to transparency limiting the energy gain. A transverse instability leads to a structured and inhomogeneous ion distribution.

  16. High energy gain in three-dimensional simulations of light sail acceleration

    International Nuclear Information System (INIS)

    Sgattoni, A.; Sinigardi, S.; Macchi, A.

    2014-01-01

    The dynamics of radiation pressure acceleration in the relativistic light sail regime are analysed by means of large scale, three-dimensional (3D) particle-in-cell simulations. Differently to other mechanisms, the 3D dynamics leads to faster and higher energy gain than in 1D or 2D geometry. This effect is caused by the local decrease of the target density due to transverse expansion leading to a “lighter sail.” However, the rarefaction of the target leads to an earlier transition to transparency limiting the energy gain. A transverse instability leads to a structured and inhomogeneous ion distribution.

  17. Three-dimensional particle image velocimetry measurement technique

    International Nuclear Information System (INIS)

    Hassan, Y.A.; Seeley, C.H.; Henderson, J.A.; Schmidl, W.D.

    2004-01-01

    The experimental flow visualization tool, Particle Image Velocimetry (PIV), is being used to determine the velocity field in two-dimensional fluid flows. In the past few years, the technique has been improved to allow the capture of flow fields in three dimensions. This paper describes changes which were made to two existing two-dimensional tracking algorithms to enable them to track three-dimensional PIV data. Results of the tests performed on these three-dimensional routines with synthetic data are presented. Experimental data was also used to test the tracking algorithms. The test setup which was used to acquire the three-dimensional experimental data is described, along with the results from both of the tracking routines which were used to analyze the experimental data. (author)

  18. Electron and ion heating by whistler turbulence: Three-dimensional particle-in-cell simulations

    International Nuclear Information System (INIS)

    Hughes, R. Scott; Gary, S. Peter; Wang, Joseph

    2014-01-01

    Three-dimensional particle-in-cell simulations of decaying whistler turbulence are carried out on a collisionless, homogeneous, magnetized, electron-ion plasma model. In addition, the simulations use an initial ensemble of relatively long wavelength whistler modes with a broad range of initial propagation directions with an initial electron beta β e = 0.05. The computations follow the temporal evolution of the fluctuations as they cascade into broadband turbulent spectra at shorter wavelengths. Three simulations correspond to successively larger simulation boxes and successively longer wavelengths of the initial fluctuations. The computations confirm previous results showing electron heating is preferentially parallel to the background magnetic field B o , and ion heating is preferentially perpendicular to B o . The new results here are that larger simulation boxes and longer initial whistler wavelengths yield weaker overall dissipation, consistent with linear dispersion theory predictions of decreased damping, stronger ion heating, consistent with a stronger ion Landau resonance, and weaker electron heating

  19. The connection of two-particle relativistic quantum mechanics with the Bethe-Salpeter equation

    International Nuclear Information System (INIS)

    Sazdjian, H.

    1986-02-01

    We show the formal equivalence between the wave equations of two-particle relativistic quantum mechanics, based on the manifestly covariant hamiltonian formalism with constraints, and the Bethe-Salpeter equation. This is achieved by algebraically transforming the latter so as to separate it into two independent equations which match the equations of hamiltonian relativistic quantum mechanics. The first equation determines the relative time evolution of the system, while the second one yields a three-dimensional eigenvalue equation. A connection is thus established between the Bethe-Salpeter wave function and its kernel on the one hand and the quantum mechanical wave function and interaction potential on the other. For the sector of solutions of the Bethe-Salpeter equation having non-relativistic limits, this relationship can be evaluated in perturbation theory. We also device a generalized form of the instantaneous approximation which simplifies the various expressions involved in the above relations. It also permits the evaluation of the normalization condition of the quantum mechanical wave function as a three-dimensional integral

  20. Statistical thermodynamics of a two-dimensional relativistic gas.

    Science.gov (United States)

    Montakhab, Afshin; Ghodrat, Malihe; Barati, Mahmood

    2009-03-01

    In this paper we study a fully relativistic model of a two-dimensional hard-disk gas. This model avoids the general problems associated with relativistic particle collisions and is therefore an ideal system to study relativistic effects in statistical thermodynamics. We study this model using molecular-dynamics simulation, concentrating on the velocity distribution functions. We obtain results for x and y components of velocity in the rest frame (Gamma) as well as the moving frame (Gamma;{'}) . Our results confirm that Jüttner distribution is the correct generalization of Maxwell-Boltzmann distribution. We obtain the same "temperature" parameter beta for both frames consistent with a recent study of a limited one-dimensional model. We also address the controversial topic of temperature transformation. We show that while local thermal equilibrium holds in the moving frame, relying on statistical methods such as distribution functions or equipartition theorem are ultimately inconclusive in deciding on a correct temperature transformation law (if any).

  1. Relativistic two-and three-particle scattering equations using instant and light-front dynamics

    International Nuclear Information System (INIS)

    Adhikari, S.K.; Tomio, L.; Frederico, T.

    1992-01-01

    Starting from the Bethe-Salpeter equation for two particles in the ladder approximation and integrating over the time component of momentum we derive three dimensional scattering integral equations satisfying constraints of unitarity and relativity, both employing the light-front and instant-form variables. The equations we arrive at are those first derived by Weinberg and by Blankenbecler and Sugar, and are shown to be related by a transformation of variables. Hence we show how to perform and relate identical dynamical calculation using these two equations. We extends this procedure to the case of three particles interacting via two-particle separable potentials. Using light-front and instant form variables we suggest a couple of three dimensional three-particle scattering equations satisfying constraints of two and three-particle unitarity and relativity. The three-particle light-front equation is shown to be approximately related by a transformation of variables to one of the instant-form three-particle equations. (author)

  2. Size-sensitive particle trajectories in three-dimensional micro-bubble acoustic streaming flows

    Science.gov (United States)

    Volk, Andreas; Rossi, Massimiliano; Hilgenfeldt, Sascha; Rallabandi, Bhargav; Kähler, Christian; Marin, Alvaro

    2015-11-01

    Oscillating microbubbles generate steady streaming flows with interesting features and promising applications for microparticle manipulation. The flow around oscillating semi-cylindrical bubbles has been typically assumed to be independent of the axial coordinate. However, it has been recently revealed that particle motion is strongly three-dimensional: Small tracer particles follow vortical trajectories with pronounced axial displacements near the bubble, weaving a toroidal stream-surface. A well-known consequence of bubble streaming flows is size-dependent particle migration, which can be exploited for sorting and trapping of microparticles in microfluidic devices. In this talk, we will show how the three-dimensional toroidal topology found for small tracer particles is modified as the particle size increases up to 1/3 of the bubble radius. Our results show size-sensitive particle positioning along the axis of the semi-cylindrical bubble. In order to analyze the three-dimensional sorting and trapping capabilities of the system, experiments with an imposed flow and polydisperse particle solutions are also shown.

  3. Voro++: a three-dimensional Voronoi cell library in C++

    Energy Technology Data Exchange (ETDEWEB)

    Rycroft, Chris

    2009-01-15

    Voro++ is a free software library for the computation of three dimensional Voronoi cells. It is primarily designed for applications in physics and materials science, where the Voronoi tessellation can be a useful tool in the analysis of densely-packed particle systems, such as granular materials or glasses. The software comprises of several C++ classes that can be modified and incorporated into other programs. A command-line utility is also provided that can use most features of the code. Voro++ makes use of a direct cell-by-cell construction, which is particularly suited to handling special boundary conditions and walls. It employs algorithms which are tolerant for numerical precision errors, and it has been successfully employed on very large particle systems.

  4. Three-Dimensional Simulation of Ultrasound-Induced Microalgal Cell Disruption.

    Science.gov (United States)

    Wang, M; Yuan, W; Hale, Andy

    2016-03-01

    The three-dimensional distribution (x, y, and z) of ultrasound-induced microalgal cell disruption in a sonochemical reactor was predicted by solving the Helmholtz equation using a three-dimensional acoustic module in the COMSOL Multiphysics software. The simulated local ultrasound pressure at any given location (x, y, and z) was found to correlate with cell disruption of a freshwater alga, Scenedesmus dimorphus, represented by the change of algal cell particle/debris concentration, chlorophyll-a fluorescence density (CAFD), and Nile red stained lipid fluorescence density (LFD), which was also validated by the model reaction of potassium iodide oxidation (the Weissler reaction). Furthermore, the effect of ultrasound power intensity and processing duration on algal cell disruption was examined to address the limitation of the model.

  5. Spinning relativistic particles in external fields

    International Nuclear Information System (INIS)

    Pomeranskii, Andrei A; Sen'kov, Roman A; Khriplovich, Iosif B

    2000-01-01

    The motion of spinning relativistic particles in external electromagnetic and gravitational fields is considered. The self-consistent equations of motion are built with the noncovariant description of spin and with the usual, 'naive' definition of the coordinate of a relativistic particle. A simple derivation of the gravitational interaction of first order in spin is presented for a relativistic particle. The approach developed allows one to consider effects of higher order in spin. Concrete calculations are performed for the second order. The gravimagnetic moment is discussed, a special spin effect in general relativity. We also consider the contributions of the spin interactions of first and second order to the gravitational radiation of compact binary stars. (from the current literature)

  6. Progress of laser-plasma interaction simulations with the particle-in-cell code

    International Nuclear Information System (INIS)

    Sakagami, Hitoshi; Kishimoto, Yasuaki; Sentoku, Yasuhiko; Taguchi, Toshihiro

    2005-01-01

    As the laser-plasma interaction is a non-equilibrium, non-linear and relativistic phenomenon, we must introduce a microscopic method, namely, the relativistic electromagnetic PIC (Particle-In-Cell) simulation code. The PIC code requires a huge number of particles to validate simulation results, and its task is very computation-intensive. Thus simulation researches by the PIC code have been progressing along with advances in computer technology. Recently, parallel computers with tremendous computational power have become available, and thus we can perform three-dimensional PIC simulations for the laser-plasma interaction to investigate laser fusion. Some simulation results are shown with figures. We discuss a recent trend of large-scale PIC simulations that enable direct comparison between experimental facts and computational results. We also discharge/lightning simulations by the extended PIC code, which include various atomic and relaxation processes. (author)

  7. Quasi-three-dimensional particle imaging with digital holography.

    Science.gov (United States)

    Kemppinen, Osku; Heinson, Yuli; Berg, Matthew

    2017-05-01

    In this work, approximate three-dimensional structures of microparticles are generated with digital holography using an automated focus method. This is done by stacking a collection of silhouette-like images of a particle reconstructed from a single in-line hologram. The method enables estimation of the particle size in the longitudinal and transverse dimensions. Using the discrete dipole approximation, the method is tested computationally by simulating holograms for a variety of particles and attempting to reconstruct the known three-dimensional structure. It is found that poor longitudinal resolution strongly perturbs the reconstructed structure, yet the method does provide an approximate sense for the structure's longitudinal dimension. The method is then applied to laboratory measurements of holograms of single microparticles and their scattering patterns.

  8. Higher-dimensional relativistic-fluid spheres

    International Nuclear Information System (INIS)

    Patel, L. K.; Ahmedabad, Gujarat Univ.

    1997-01-01

    They consider the hydrostatic equilibrium of relativistic-fluid spheres for a D-dimensional space-time. Three physically viable interior solutions of the Einstein field equations corresponding to perfect-fluid spheres in a D-dimensional space-time are obtained. When D = 4 they reduce to the Tolman IV solution, the Mehra solution and the Finch-Skea solution. The solutions are smoothly matched with the D-dimensional Schwarzschild exterior solution at the boundary r = a of the fluid sphere. Some physical features and other related details of the solutions are briefly discussed. A brief description of two other new solutions for higher-dimensional perfect-fluid spheres is also given

  9. GENERAL-RELATIVISTIC SIMULATIONS OF THREE-DIMENSIONAL CORE-COLLAPSE SUPERNOVAE

    Energy Technology Data Exchange (ETDEWEB)

    Ott, Christian D.; Abdikamalov, Ernazar; Moesta, Philipp; Haas, Roland; Drasco, Steve; O' Connor, Evan P.; Reisswig, Christian [TAPIR, Mailcode 350-17, California Institute of Technology, Pasadena, CA 91125 (United States); Meakin, Casey A. [Theoretical Division, Los Alamos National Laboratory, Los Alamos, NM (United States); Schnetter, Erik, E-mail: cott@tapir.caltech.edu [Perimeter Institute for Theoretical Physics, Waterloo, ON (Canada)

    2013-05-10

    We study the three-dimensional (3D) hydrodynamics of the post-core-bounce phase of the collapse of a 27 M{sub Sun} star and pay special attention to the development of the standing accretion shock instability (SASI) and neutrino-driven convection. To this end, we perform 3D general-relativistic simulations with a three-species neutrino leakage scheme. The leakage scheme captures the essential aspects of neutrino cooling, heating, and lepton number exchange as predicted by radiation-hydrodynamics simulations. The 27 M{sub Sun} progenitor was studied in 2D by Mueller et al., who observed strong growth of the SASI while neutrino-driven convection was suppressed. In our 3D simulations, neutrino-driven convection grows from numerical perturbations imposed by our Cartesian grid. It becomes the dominant instability and leads to large-scale non-oscillatory deformations of the shock front. These will result in strongly aspherical explosions without the need for large-scale SASI shock oscillations. Low-l-mode SASI oscillations are present in our models, but saturate at small amplitudes that decrease with increasing neutrino heating and vigor of convection. Our results, in agreement with simpler 3D Newtonian simulations, suggest that once neutrino-driven convection is started, it is likely to become the dominant instability in 3D. Whether it is the primary instability after bounce will ultimately depend on the physical seed perturbations present in the cores of massive stars. The gravitational wave signal, which we extract and analyze for the first time from 3D general-relativistic models, will serve as an observational probe of the postbounce dynamics and, in combination with neutrinos, may allow us to determine the primary hydrodynamic instability.

  10. GENERAL-RELATIVISTIC SIMULATIONS OF THREE-DIMENSIONAL CORE-COLLAPSE SUPERNOVAE

    International Nuclear Information System (INIS)

    Ott, Christian D.; Abdikamalov, Ernazar; Mösta, Philipp; Haas, Roland; Drasco, Steve; O'Connor, Evan P.; Reisswig, Christian; Meakin, Casey A.; Schnetter, Erik

    2013-01-01

    We study the three-dimensional (3D) hydrodynamics of the post-core-bounce phase of the collapse of a 27 M ☉ star and pay special attention to the development of the standing accretion shock instability (SASI) and neutrino-driven convection. To this end, we perform 3D general-relativistic simulations with a three-species neutrino leakage scheme. The leakage scheme captures the essential aspects of neutrino cooling, heating, and lepton number exchange as predicted by radiation-hydrodynamics simulations. The 27 M ☉ progenitor was studied in 2D by Müller et al., who observed strong growth of the SASI while neutrino-driven convection was suppressed. In our 3D simulations, neutrino-driven convection grows from numerical perturbations imposed by our Cartesian grid. It becomes the dominant instability and leads to large-scale non-oscillatory deformations of the shock front. These will result in strongly aspherical explosions without the need for large-scale SASI shock oscillations. Low-l-mode SASI oscillations are present in our models, but saturate at small amplitudes that decrease with increasing neutrino heating and vigor of convection. Our results, in agreement with simpler 3D Newtonian simulations, suggest that once neutrino-driven convection is started, it is likely to become the dominant instability in 3D. Whether it is the primary instability after bounce will ultimately depend on the physical seed perturbations present in the cores of massive stars. The gravitational wave signal, which we extract and analyze for the first time from 3D general-relativistic models, will serve as an observational probe of the postbounce dynamics and, in combination with neutrinos, may allow us to determine the primary hydrodynamic instability.

  11. Three-dimensional particle-in-cell simulation on gain saturation effect of microchannel plate

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Qiangqiang; Yuan, Zheng; Cao, Zhurong, E-mail: cao33jin@aliyun.com; Deng, Bo; Chen, Tao; Deng, Keli [Research Center of Laser Fusion, Chinese Academy of Engineering Physics, Mianyang, Sichuan 621900 (China)

    2016-07-15

    We present here the results of the simulation work, using the three-dimensional particle-in-cell method, on the performance of the lead glass microchannel plate under saturated state. We calculated the electron cascade process with different DC bias voltages under both self-consistent condition and non-self-consistent condition. The comparative results have demonstrated that the strong self-consistent field can suppress the cascade process and make the microchannel plate saturated. The simulation results were also compared to the experimental data and good agreement was obtained. The simulation results also show that the electron multiplication process in the channel is accompanied by the buildup process of positive charges in the channel wall. Though the interactions among the secondary electron cloud in the channel, the positive charges in the channel wall, and the external acceleration field can make the electron-surface collision more frequent, the collision energy will be inevitably reduced, thus the electron gain will also be reduced.

  12. Quantum mechanics of relativistic particles in multiply connected spaces and the Aharonov-Bohm effect

    International Nuclear Information System (INIS)

    Gamboa, J.; Rivelles, V.O.

    1990-04-01

    We consider the motion of free relativistic particles in multiply connected spaces. We show that if one of the spatial dimensions has the topology of a circle then the D dimensional spacetime is compactified to D-1 dimensions and the particle mass increases by an amount which is proportional to a quantum phase factor and inversely proportional to the radius of the circle. We also consider the relativistic Aharonov-Bohm effect and we show that the interference pattern is a universal characteristic due only to the topological properties of the experimental situation and not to the intrinsic properties of the particle. The propagators are calculated in both situations. (author) [pt

  13. Auroral kilometric radiation - An example of relativistic wave-particle interaction in geoplasma

    International Nuclear Information System (INIS)

    Pritchett, P.L.

    1990-01-01

    The earth's auroral kilometric radiation (AKR) is believed to be produced by the electron-cyclotron maser instability. This instability is the result of a wave-particle interaction in which relativistic effects are crucial. An explanation is given as to how these relativistic effects alter the shape of the resonance curve in velocity space and modify the R - X mode wave dispersion near the electron cyclotron frequency compared to the results obtained in the nonrelativistic limit and from cold-plasma theory. The properties of the cyclotron maser instability in a driven system are illustrated using two-dimensional electromagnetic particle simulations which incorporate a continual flow of primary energetic electrons along the magnetic field. 31 refs

  14. Anomalous dimension in three-dimensional semiclassical gravity

    International Nuclear Information System (INIS)

    Alesci, Emanuele; Arzano, Michele

    2012-01-01

    The description of the phase space of relativistic particles coupled to three-dimensional Einstein gravity requires momenta which are coordinates on a group manifold rather than on ordinary Minkowski space. The corresponding field theory turns out to be a non-commutative field theory on configuration space and a group field theory on momentum space. Using basic non-commutative Fourier transform tools we introduce the notion of non-commutative heat-kernel associated with the Laplacian on the non-commutative configuration space. We show that the spectral dimension associated to the non-commutative heat kernel varies with the scale reaching a non-integer value smaller than three for Planckian diffusion scales.

  15. Non-relativistic spinning particle in a Newton-Cartan background

    Science.gov (United States)

    Barducci, Andrea; Casalbuoni, Roberto; Gomis, Joaquim

    2018-01-01

    We construct the action of a non-relativistic spinning particle moving in a general torsionless Newton-Cartan background. The particle does not follow the geodesic equations, instead the motion is governed by the non-relativistic analog of Papapetrou equation. The spinning particle is described in terms of Grassmann variables. In the flat case the action is invariant under the non-relativistic analog of space-time vector supersymmetry.

  16. Biquaternions and relativistic kinematics

    International Nuclear Information System (INIS)

    Bogush, A.A.; Kurochkin, Yu.A.; Fedorov, F.I.

    1979-01-01

    The problems concerning the use of quaternion interpretation of the Lorentz group vector parametrization are considered for solving relativistic kinematics problems. A vector theory convenient for describing the characteristic features of the Lobachevsky space is suggested. The kinematics of elementary particle scattering is investigated on the basis of this theory. A synthesis of vector parametrization and of quaternion calculation has been shown to lead to natural formulation of the theory of vectors in the three-dimensional Lobachevsky space, realized on mass hyperboloids of relativistic particles

  17. An incompressible two-dimensional multiphase particle-in-cell model for dense particle flows

    Energy Technology Data Exchange (ETDEWEB)

    Snider, D.M. [SAIC, Albuquerque, NM (United States); O`Rourke, P.J. [Los Alamos National Lab., NM (United States); Andrews, M.J. [Texas A and M Univ., College Station, TX (United States). Dept. of Mechanical Engineering

    1997-06-01

    A two-dimensional, incompressible, multiphase particle-in-cell (MP-PIC) method is presented for dense particle flows. The numerical technique solves the governing equations of the fluid phase using a continuum model and those of the particle phase using a Lagrangian model. Difficulties associated with calculating interparticle interactions for dense particle flows with volume fractions above 5% have been eliminated by mapping particle properties to a Eulerian grid and then mapping back computed stress tensors to particle positions. This approach utilizes the best of Eulerian/Eulerian continuum models and Eulerian/Lagrangian discrete models. The solution scheme allows for distributions of types, sizes, and density of particles, with no numerical diffusion from the Lagrangian particle calculations. The computational method is implicit with respect to pressure, velocity, and volume fraction in the continuum solution thus avoiding courant limits on computational time advancement. MP-PIC simulations are compared with one-dimensional problems that have analytical solutions and with two-dimensional problems for which there are experimental data.

  18. Relativistic effects in the energy loss of a fast charged particle moving parallel to a two-dimensional electron gas

    Science.gov (United States)

    Mišković, Zoran L.; Akbari, Kamran; Segui, Silvina; Gervasoni, Juana L.; Arista, Néstor R.

    2018-05-01

    We present a fully relativistic formulation for the energy loss rate of a charged particle moving parallel to a sheet containing two-dimensional electron gas, allowing that its in-plane polarization may be described by different longitudinal and transverse conductivities. We apply our formulation to the case of a doped graphene layer in the terahertz range of frequencies, where excitation of the Dirac plasmon polariton (DPP) in graphene plays a major role. By using the Drude model with zero damping we evaluate the energy loss rate due to excitation of the DPP, and show that the retardation effects are important when the incident particle speed and its distance from graphene both increase. Interestingly, the retarded energy loss rate obtained in this manner may be both larger and smaller than its non-retarded counterpart for different combinations of the particle speed and distance.

  19. New relativistic particle-in-cell simulation studies of prompt and early afterglows from GRBs

    International Nuclear Information System (INIS)

    Ken-Ichi Nishikawa

    2008-01-01

    Nonthermal radiation observed from astrophysical systems containing relativistic jets and shocks, e.g., gamma-ray bursts (GRBs), active galactic nuclei (AGNs), and Galactic microquasar systems usually have power-law emission spectra. Recent PIC simulations of relativistic electron-ion (electro-positron) jets injected into a stationary medium show that particle acceleration occurs within the downstream jet. In the collisionless relativistic shock particle acceleration is due to plasma waves and their associated instabilities (e.g., the Buneman instability, other two-streaming instability, and the Weibel (filamentation) instability) created in the shocks are responsible for particle (electron, positron, and ion) acceleration. The simulation results show that the Weibel instability is responsible for generating and amplifying highly nonuniform, small-scale magnetic fields. These magnetic fields contribute to the electrons' transverse deflection behind the jet head. The '' jitter '' radiation from deflected electrons has different properties than synchrotron radiation which is calculated in a uniform magnetic field. This jitter radiation may be important to understanding the complex time evolution and/or spectral structure in gamma-ray bursts, relativistic jets, and supernova remnants. (author)

  20. Particle Acceleration and Magnetic Field Generation in Electron-Positron Relativistic Shocks

    Science.gov (United States)

    Nishikawa, K.-I.; Hardee, P.; Richardson, G.; Preece, R.; Sol, H.; Fishman, G. J.

    2005-01-01

    Shock acceleration is a ubiquitous phenomenon in astrophysical plasmas. Plasma waves and their associated instabilities (e.g., Buneman, Weibel, and other two-stream instabilities) created in collisionless shocks are responsible for particle (electron, positron, and ion) acceleration. Using a three-dimensional relativistic electromagnetic particle (REMP) code, we have investigated particle acceleration associated with a relativistic electron-positron jet front propagating into an ambient electron-positron plasma with and without initial magnetic fields. We find small differences in the results for no ambient and modest ambient magnetic fields. New simulations show that the Weibel instability created in the collisionless shock front accelerates jet and ambient particles both perpendicular and parallel to the jet propagation direction. Furthermore, the nonlinear fluctuation amplitudes of densities, currents, and electric and magnetic fields in the electron-positron shock are larger than those found in the electron-ion shock studied in a previous paper at a comparable simulation time. This comes from the fact that both electrons and positrons contribute to generation of the Weibel instability. In addition, we have performed simulations with different electron skin depths. We find that growth times scale inversely with the plasma frequency, and the sizes of structures created by tine Weibel instability scale proportionally to the electron skin depth. This is the expected result and indicates that the simulations have sufficient grid resolution. While some Fermi acceleration may occur at the jet front, the majority of electron and positron acceleration takes place behind the jet front and cannot be characterized as Fermi acceleration. The simulation results show that the Weibel instability is responsible for generating and amplifying nonuniform, small-scale magnetic fields, which contribute to the electron s (positron s) transverse deflection behind the jet head. This

  1. THREE-DIMENSIONAL BOLTZMANN HYDRO CODE FOR CORE COLLAPSE IN MASSIVE STARS. I. SPECIAL RELATIVISTIC TREATMENTS

    International Nuclear Information System (INIS)

    Nagakura, Hiroki; Sumiyoshi, Kohsuke; Yamada, Shoichi

    2014-01-01

    We propose a novel numerical method for solving multi-dimensional, special relativistic Boltzmann equations for neutrinos coupled with hydrodynamics equations. This method is meant to be applied to simulations of core-collapse supernovae. We handle special relativity in a non-conventional way, taking account of all orders of v/c. Consistent treatment of the advection and collision terms in the Boltzmann equations has been a challenge, which we overcome by employing two different energy grids: Lagrangian remapped and laboratory fixed grids. We conduct a series of basic tests and perform a one-dimensional simulation of core-collapse, bounce, and shock-stall for a 15 M ☉ progenitor model with a minimum but essential set of microphysics. We demonstrate in the latter simulation that our new code is capable of handling all phases in core-collapse supernova. For comparison, a non-relativistic simulation is also conducted with the same code, and we show that they produce qualitatively wrong results in neutrino transfer. Finally, we discuss a possible incorporation of general relativistic effects into our method

  2. The dynamics of low-β plasma clouds as simulated by a three-dimensional, electromagnetic particle code

    International Nuclear Information System (INIS)

    Neubert, T.; Miller, R.H.; Buneman, O.; Nishikawa, K.I.

    1992-01-01

    The dynamics of low-β plasma clouds moving perpendicular to an ambient magnetic field in vacuum and in a background plasma is simulated by means of a three-dimensional, electromagnetic, and relativistic particle simulation code. The simulations show the formation of the space charge sheaths at the sides of the cloud with the associated polarization electric field which facilitate the cross-field propagation, as well as the sheaths at the front and rear end of the cloud caused by the larger ion Larmor radius, which allows ions to move ahead and lag behind the electrons as they gyrate. Results on the cloud dynamics and electromagnetic radiation include the following: (1) In a background plasma, electron and ion sheaths expand along the magnetic field at the same rate, whereas in vacuum the electron sheath expands much faster than the ion sheath. (2) Sheath electrons are accelerated up to relativistic energies. This result indicates that artificial plasma clouds released in the ionosphere or magnetosphere may generate optical emissions (aurora) as energetic sheath electrons scatter in the upper atmosphere. (3) The expansion of the electron sheaths is analogous to the ejection of high-intensity electron beams from spacecraft. (4) Second-order and higher-order sheaths are formed which extend out into the ambient plasma. (5) Formation of the sheaths and the polarization field reduces the forward momentum of the cloud. (6) The coherent component of the particle gyromotion is damped in time as the particles establish a forward directed drift velocity. (7) The coherent particle gyrations generate electromagnetic radiation

  3. Simulating three-dimensional nonthermal high-energy photon emission in colliding-wind binaries

    Energy Technology Data Exchange (ETDEWEB)

    Reitberger, K.; Kissmann, R.; Reimer, A.; Reimer, O., E-mail: klaus.reitberger@uibk.ac.at [Institut für Astro- und Teilchenphysik and Institut für Theoretische Physik, Leopold-Franzens-Universität Innsbruck, A-6020 Innsbruck (Austria)

    2014-07-01

    Massive stars in binary systems have long been regarded as potential sources of high-energy γ rays. The emission is principally thought to arise in the region where the stellar winds collide and accelerate relativistic particles which subsequently emit γ rays. On the basis of a three-dimensional distribution function of high-energy particles in the wind collision region—as obtained by a numerical hydrodynamics and particle transport model—we present the computation of the three-dimensional nonthermal photon emission for a given line of sight. Anisotropic inverse Compton emission is modeled using the target radiation field of both stars. Photons from relativistic bremsstrahlung and neutral pion decay are computed on the basis of local wind plasma densities. We also consider photon-photon opacity effects due to the dense radiation fields of the stars. Results are shown for different stellar separations of a given binary system comprising of a B star and a Wolf-Rayet star. The influence of orbital orientation with respect to the line of sight is also studied by using different orbital viewing angles. For the chosen electron-proton injection ratio of 10{sup –2}, we present the ensuing photon emission in terms of two-dimensional projections maps, spectral energy distributions, and integrated photon flux values in various energy bands. Here, we find a transition from hadron-dominated to lepton-dominated high-energy emission with increasing stellar separations. In addition, we confirm findings from previous analytic modeling that the spectral energy distribution varies significantly with orbital orientation.

  4. Particle acceleration in relativistic magnetic flux-merging events

    Science.gov (United States)

    Lyutikov, Maxim; Sironi, Lorenzo; Komissarov, Serguei S.; Porth, Oliver

    2017-12-01

    Using analytical and numerical methods (fluid and particle-in-cell simulations) we study a number of model problems involving merger of magnetic flux tubes in relativistic magnetically dominated plasma. Mergers of current-carrying flux tubes (exemplified by the two-dimensional `ABC' structures) and zero-total-current magnetic flux tubes are considered. In all cases regimes of spontaneous and driven evolution are investigated. We identify two stages of particle acceleration during flux mergers: (i) fast explosive prompt X-point collapse and (ii) ensuing island merger. The fastest acceleration occurs during the initial catastrophic X-point collapse, with the reconnection electric field of the order of the magnetic field. During the X-point collapse, particles are accelerated by charge-starved electric fields, which can reach (and even exceed) values of the local magnetic field. The explosive stage of reconnection produces non-thermal power-law tails with slopes that depend on the average magnetization . For plasma magnetization 2$ the spectrum power-law index is 2$ ; in this case the maximal energy depends linearly on the size of the reconnecting islands. For higher magnetization, 2$ , the spectra are hard, , yet the maximal energy \\text{max}$ can still exceed the average magnetic energy per particle, , by orders of magnitude (if is not too close to unity). The X-point collapse stage is followed by magnetic island merger that dissipates a large fraction of the initial magnetic energy in a regime of forced magnetic reconnection, further accelerating the particles, but proceeds at a slower reconnection rate.

  5. Non-thermal particle acceleration in collisionless relativistic electron-proton reconnection

    Science.gov (United States)

    Werner, G. R.; Uzdensky, D. A.; Begelman, M. C.; Cerutti, B.; Nalewajko, K.

    2018-02-01

    Magnetic reconnection in relativistic collisionless plasmas can accelerate particles and power high-energy emission in various astrophysical systems. Whereas most previous studies focused on relativistic reconnection in pair plasmas, less attention has been paid to electron-ion plasma reconnection, expected in black hole accretion flows and relativistic jets. We report a comprehensive particle-in-cell numerical investigation of reconnection in an electron-ion plasma, spanning a wide range of ambient ion magnetizations σi, from the semirelativistic regime (ultrarelativistic electrons but non-relativistic ions, 10-3 ≪ σi ≪ 1) to the fully relativistic regime (both species are ultrarelativistic, σi ≫ 1). We investigate how the reconnection rate, electron and ion plasma flows, electric and magnetic field structures, electron/ion energy partitioning, and non-thermal particle acceleration depend on σi. Our key findings are: (1) the reconnection rate is about 0.1 of the Alfvénic rate across all regimes; (2) electrons can form concentrated moderately relativistic outflows even in the semirelativistic, small-σi regime; (3) while the released magnetic energy is partitioned equally between electrons and ions in the ultrarelativistic limit, the electron energy fraction declines gradually with decreased σi and asymptotes to about 0.25 in the semirelativistic regime; and (4) reconnection leads to efficient non-thermal electron acceleration with a σi-dependent power-law index, p(σ _i)˜eq const+0.7σ _i^{-1/2}. These findings are important for understanding black hole systems and lend support to semirelativistic reconnection models for powering non-thermal emission in blazar jets, offering a natural explanation for the spectral indices observed in these systems.

  6. Inductive and electrostatic acceleration in relativistic jet-plasma interactions.

    Science.gov (United States)

    Ng, Johnny S T; Noble, Robert J

    2006-03-24

    We report on the observation of rapid particle acceleration in numerical simulations of relativistic jet-plasma interactions and discuss the underlying mechanisms. The dynamics of a charge-neutral, narrow, electron-positron jet propagating through an unmagnetized electron-ion plasma was investigated using a three-dimensional, electromagnetic, particle-in-cell computer code. The interaction excited magnetic filamentation as well as electrostatic plasma instabilities. In some cases, the longitudinal electric fields generated inductively and electrostatically reached the cold plasma-wave-breaking limit, and the longitudinal momentum of about half the positrons increased by 50% with a maximum gain exceeding a factor of 2 during the simulation period. Particle acceleration via these mechanisms occurred when the criteria for Weibel instability were satisfied.

  7. Relativistic particle with the action dependent on the torsion of its world trajectory

    International Nuclear Information System (INIS)

    Nesterenko, V.V.

    1990-01-01

    The generalized Hamiltonian formalism for the relativistic particle with a torsion in a D-dimensional space-time is constructed. A complete set of the constraints in the phase space is obtained and their division into the first-class and the second-class constraints is accomplished. On this basis the canonical quantization of the model is fulfilled. For D=3 the mass spectrum is obtained explicitly, the mass of the state being dependent on its spin. The possibility of describing in the framework of this model the states with integer, half-integer and continuous spins is discussed. The wave equation and the propagator are found in the operator form. The mass formula is obtained also in the model of a relativistic particles with curvature in a D-dimensional space-time. 34 refs

  8. Propagation of localized structures in relativistic magnetized electron-positron plasmas using particle-in-cell simulations

    Energy Technology Data Exchange (ETDEWEB)

    López, Rodrigo A. [Departamento de Física, Facultad de Ciencias Físicas y Matemáticas, Universidad de Concepción, Concepción 4070386 (Chile); Muñoz, Víctor [Departamento de Física, Facultad de Ciencias, Universidad de Chile, Casilla 653, Santiago (Chile); Viñas, Adolfo F. [Geospace Physics Laboratory, Heliophysics Science Division, NASA Goddard Space Flight Center, Greenbelt, Maryland 20771 (United States); Valdivia, Juan A. [Departamento de Física, Facultad de Ciencias, Universidad de Chile, Casilla 653, Santiago (Chile); Centro para el Desarrollo de la Nanociencia y la Nanotecnología (CEDENNA), Santiago 9170124 (Chile)

    2015-09-15

    We use a particle-in-cell simulation to study the propagation of localized structures in a magnetized electron-positron plasma with relativistic finite temperature. We use as initial condition for the simulation an envelope soliton solution of the nonlinear Schrödinger equation, derived from the relativistic two fluid equations in the strongly magnetized limit. This envelope soliton turns out not to be a stable solution for the simulation and splits in two localized structures propagating in opposite directions. However, these two localized structures exhibit a soliton-like behavior, as they keep their profile after they collide with each other due to the periodic boundary conditions. We also observe the formation of localized structures in the evolution of a spatially uniform circularly polarized Alfvén wave. In both cases, the localized structures propagate with an amplitude independent velocity.

  9. Propagation of localized structures in relativistic magnetized electron-positron plasmas using particle-in-cell simulations

    International Nuclear Information System (INIS)

    López, Rodrigo A.; Muñoz, Víctor; Viñas, Adolfo F.; Valdivia, Juan A.

    2015-01-01

    We use a particle-in-cell simulation to study the propagation of localized structures in a magnetized electron-positron plasma with relativistic finite temperature. We use as initial condition for the simulation an envelope soliton solution of the nonlinear Schrödinger equation, derived from the relativistic two fluid equations in the strongly magnetized limit. This envelope soliton turns out not to be a stable solution for the simulation and splits in two localized structures propagating in opposite directions. However, these two localized structures exhibit a soliton-like behavior, as they keep their profile after they collide with each other due to the periodic boundary conditions. We also observe the formation of localized structures in the evolution of a spatially uniform circularly polarized Alfvén wave. In both cases, the localized structures propagate with an amplitude independent velocity

  10. Pseudo three-dimensional modeling of particle-fuel packing using distinct element method

    International Nuclear Information System (INIS)

    Yuki, Daisuke; Takata, Takashi; Yamaguchi, Akira

    2007-01-01

    Vibration-based packing of sphere-pac fuel is a key technology in a nuclear fuel manufacturing. In the production process of sphere-pac fuel, a Mixed Oxide (MOX) fuel is formed to spherical form and is packed in a cladding tube by adding a vibration force. In the present study, we have developed a numerical simulation method to investigate the behavior of the particles in a vibrated tube using the Distinct Element Method (DEM). In general, the DEM requires a significant computational cost. Therefore we propose a new approach in which a small particle can move through the space between three larger particles even in the two-dimensional simulation. We take into account an equivalent three-dimensional effect in the equations of motion. Thus it is named pseudo three-dimensional modeling. (author)

  11. Three-dimensional electromagnetic solitary waves in an underdense plasma in PIC simulations

    International Nuclear Information System (INIS)

    Bulanov, Sergei; Esirkepov, Timur; Nishihara, Katsunobu; Pegoraro, Francesco

    2002-01-01

    A three-dimensional sub-cycle relativistic electromagnetic soliton has been observed for the first time in a 3D Particle-in-Cell simulation of the propagation of an intense short laser pulse in an underdense plasma. The structure of the 3D soliton is identified. It resembles an oscillating electric dipole and has a strong charge separation and toroidal magnetic field component. We call this structure a TM-soliton (transverse magnetic). The 3D TM-soliton resembles a 2D P-soliton in the plane of electric field polarization, and a 2D S-soliton in the perpendicular plane. The core of the soliton is positively charged on average in time, and this results in its Coulomb explosion and in ion heating. Then the soliton evolves into a post-soliton, which is a slowly expanding quasi-neutral cavity in the plasma

  12. Tachyonless models of relativistic particles with curvature and torsion

    International Nuclear Information System (INIS)

    Kuznetsov, Yu.A.; Plyushchaj, M.S.

    1992-01-01

    The problem of construction (2+1)-dimensional tachyonless models of relativistic particles with an action depending on the world-trajectory curvature and torsion is investigated. The special class of models, described by maximum symmetric action and comprising only spin internal degrees of freedom is found. The examples of systems from the special class are given, whose classical and quantum spectra contain only massive states. 23 refs

  13. Three-particle physics and dispersion relation theory

    CERN Document Server

    Anisovich, A V; Matveev, M A; Nikonov, V A; Nyiri, J; Sarantsev, A V

    2013-01-01

    The necessity of describing three-nucleon and three-quark systems have led to a constant interest in the problem of three particles. The question of including relativistic effects appeared together with the consideration of the decay amplitude in the framework of the dispersion technique. The relativistic dispersion description of amplitudes always takes into account processes connected with the investigated reaction by the unitarity condition or by virtual transitions; in the case of three-particle processes they are, as a rule, those where other many-particle states and resonances are produced. The description of these interconnected reactions and ways of handling them is the main subject of the book.

  14. A Non-Perturbative, Finite Particle Number Approach to Relativistic Scattering Theory

    Energy Technology Data Exchange (ETDEWEB)

    Lindesay, James V

    2001-05-11

    We present integral equations for the scattering amplitudes of three scalar particles, using the Faddeev channel decomposition, which can be readily extended to any finite number of particles of any helicity. The solution of these equations, which have been demonstrated to be calculable, provide a non-perturbative way of obtaining relativistic scattering amplitudes for any finite number of particles that are Lorentz invariant, unitary, cluster decomposable and reduce unambiguously in the non-relativistic limit to the non-relativistic Faddeev equations. The aim of this program is to develop equations which explicitly depend upon physically observable input variables, and do not require ''renormalization'' or ''dressing'' of these parameters to connect them to the boundary states.

  15. Relativistic non-Hamiltonian mechanics

    International Nuclear Information System (INIS)

    Tarasov, Vasily E.

    2010-01-01

    Relativistic particle subjected to a general four-force is considered as a nonholonomic system. The nonholonomic constraint in four-dimensional space-time represents the relativistic invariance by the equation for four-velocity u μ u μ + c 2 = 0, where c is the speed of light in vacuum. In the general case, four-forces are non-potential, and the relativistic particle is a non-Hamiltonian system in four-dimensional pseudo-Euclidean space-time. We consider non-Hamiltonian and dissipative systems in relativistic mechanics. Covariant forms of the principle of stationary action and the Hamilton's principle for relativistic mechanics of non-Hamiltonian systems are discussed. The equivalence of these principles is considered for relativistic particles subjected to potential and non-potential forces. We note that the equations of motion which follow from the Hamilton's principle are not equivalent to the equations which follow from the variational principle of stationary action. The Hamilton's principle and the principle of stationary action are not compatible in the case of systems with nonholonomic constraint and the potential forces. The principle of stationary action for relativistic particle subjected to non-potential forces can be used if the Helmholtz conditions are satisfied. The Hamilton's principle and the principle of stationary action are equivalent only for a special class of relativistic non-Hamiltonian systems.

  16. Relativistic shocks and particle acceleration

    International Nuclear Information System (INIS)

    Heavens, A.F.

    1988-01-01

    In this paper, we investigate the fluid dynamics of relativistic shock waves, and use the results to calculate the spectral index of particles accelerated by the Fermi process in such shocks. We have calculated the distributions of Fermi-accelerated particles at shocks propagating into cold proton-electron plasma and also cold electron-positron plasma. We have considered two different power spectra for the scattering waves, and find, in contrast to the non-relativistic case, that the spectral index of the accelerated particles depends on the wave power spectrum. On the assumption of thermal equilibrium both upstream and downstream, we present some useful fits for the compression ratio of shocks propagating at arbitrary speeds into gas of any temperature. (author)

  17. Canonical quantization of spinning relativistic particle in external backgrounds

    Energy Technology Data Exchange (ETDEWEB)

    Gavrilov, S.P. [Universidade Federal de Sergipe (UFS), Aracaju, SE (Brazil); Gitman, D.M. [Sao Paulo Univ. (USP), SP (Brazil). Inst. de Fisica

    2000-07-01

    Full text follows: We revise the problem of the quantization of spinning relativistic particle pseudoclassical model, using a modified consistent canonical scheme. It allows one not only to include arbitrary electromagnetic and gravitational backgrounds in the consideration but to get in course of the quantization a consistent relativistic quantum mechanics, which reproduces literally the behavior of the one-particle sector of quantized spinor field. In particular, in a physical sector of the Hilbert space a complete positive spectrum of energies of relativistic particles and antiparticles is reproduced. Requirement to maintain all classical symmetries under the coordinate transformations and under U(1) transformations allows one to realize operator algebra without any ambiguities. (author)

  18. Three-dimensional visualization of forming Hepatitis C virus-like particles by electron-tomography

    Energy Technology Data Exchange (ETDEWEB)

    Badia-Martinez, Daniel; Peralta, Bibiana [Structural Biology Unit, CIC bioGUNE, CIBERehd, 48160 Derio (Spain); Andres, German; Guerra, Milagros [Electron Microscopy Unit, Centro de Biologia Molecular Severo Ochoa, CSIC-UAM, Campus Cantoblanco, 28049 Madrid (Spain); Gil-Carton, David [Structural Biology Unit, CIC bioGUNE, CIBERehd, 48160 Derio (Spain); Abrescia, Nicola G.A., E-mail: nabrescia@cicbiogune.es [Structural Biology Unit, CIC bioGUNE, CIBERehd, 48160 Derio (Spain); IKERBASQUE, Basque Foundation for Science, 48011 Bilbao (Spain)

    2012-09-01

    Hepatitis C virus infects almost 170 million people per year but its assembly pathway, architecture and the structures of its envelope proteins are poorly understood. Using electron tomography of plastic-embedded sections of insect cells, we have visualized the morphogenesis of recombinant Hepatitis C virus-like particles. Our data provide a three-dimensional sketch of viral assembly at the endoplasmic reticulum showing different budding stages and contiguity of buds. This latter phenomenon could play an important role during the assembly of wt-HCV and explain the size-heterogeneity of its particles.

  19. Three-dimensional visualization of forming Hepatitis C virus-like particles by electron-tomography

    International Nuclear Information System (INIS)

    Badia-Martinez, Daniel; Peralta, Bibiana; Andrés, German; Guerra, Milagros; Gil-Carton, David; Abrescia, Nicola G.A.

    2012-01-01

    Hepatitis C virus infects almost 170 million people per year but its assembly pathway, architecture and the structures of its envelope proteins are poorly understood. Using electron tomography of plastic-embedded sections of insect cells, we have visualized the morphogenesis of recombinant Hepatitis C virus-like particles. Our data provide a three-dimensional sketch of viral assembly at the endoplasmic reticulum showing different budding stages and contiguity of buds. This latter phenomenon could play an important role during the assembly of wt-HCV and explain the size-heterogeneity of its particles.

  20. Eruptive Massive Vector Particles of 5-Dimensional Kerr-Gödel Spacetime

    Science.gov (United States)

    Övgün, A.; Sakalli, I.

    2018-02-01

    In this paper, we investigate Hawking radiation of massive spin-1 particles from 5-dimensional Kerr-Gödel spacetime. By applying the WKB approximation and the Hamilton-Jacobi ansatz to the relativistic Proca equation, we obtain the quantum tunneling rate of the massive vector particles. Using the obtained tunneling rate, we show how one impeccably computes the Hawking temperature of the 5-dimensional Kerr-Gödel spacetime.

  1. Meson form factors and covariant three-dimensional formulation of composite model

    International Nuclear Information System (INIS)

    Skachkov, N.B.; Solovtsov, I.L.

    1978-01-01

    An approach is developed which is applied in the framework of the relativistic quark model to obtain explicit expressions for meson form factors in terms of covariant wave functions of the two-quark system. These wave functions obey the two-particle quasipotential equation in which the relative motion of quarks is singled out in a covariant way. The exact form of the wave functions is found using the transition to the relativistic configurational representation with the help of the harmonic analysis on the Lorentz group instead of the usual Fourier expansion and then solving the relativistic difference equation thus obtained. The expressions found for form factors are transformed into the three-dimensional covariant form which is a direct geometrical relativistic generalization of analogous expressions of the nonrelativistic quantum mechanics and provides the decrease of the meson form factor by the Fsub(π)(t) approximately t -1 law as -t infinity, in the Coulomb field

  2. On the time delay between ultra-relativistic particles

    Energy Technology Data Exchange (ETDEWEB)

    Fleury, Pierre, E-mail: pierre.fleury@uct.ac.za [Department of Mathematics and Applied Mathematics, University of Cape Town, Rondebosch 7701, Cape Town (South Africa); Department of Physics, University of the Western Cape, Robert Sobukwe Road, Bellville 7535 (South Africa)

    2016-09-10

    The time delay between the receptions of ultra-relativistic particles emitted simultaneously is a useful observable for both fundamental physics and cosmology. The expression of the delay when the particles travel through an arbitrary spacetime has been derived recently by Fanizza et al., using a particular coordinate system and self-consistent assumptions. The present article shows that this formula enjoys a simple physical interpretation: the relative velocity between two ultra-relativistic particles is constant. This result reveals an interesting kinematical property of general relativity, namely that the tidal forces experienced by ultra-relativistic particles in the direction of their motion are much smaller than those experienced orthogonally to their motion.

  3. On the time delay between ultra-relativistic particles

    International Nuclear Information System (INIS)

    Fleury, Pierre

    2016-01-01

    The time delay between the receptions of ultra-relativistic particles emitted simultaneously is a useful observable for both fundamental physics and cosmology. The expression of the delay when the particles travel through an arbitrary spacetime has been derived recently by Fanizza et al., using a particular coordinate system and self-consistent assumptions. The present article shows that this formula enjoys a simple physical interpretation: the relative velocity between two ultra-relativistic particles is constant. This result reveals an interesting kinematical property of general relativity, namely that the tidal forces experienced by ultra-relativistic particles in the direction of their motion are much smaller than those experienced orthogonally to their motion.

  4. Three-dimensional single-particle tracking in live cells: news from the third dimension

    International Nuclear Information System (INIS)

    Dupont, A; Wehnekamp, F; Katayama, Y; Lamb, D C; Gorelashvili, M; Schüller, V; Arcizet, D; Heinrich, D

    2013-01-01

    Single-particle tracking (SPT) is of growing importance in the biophysical community. It is used to investigate processes such as drug and gene delivery, viral uptake, intracellular trafficking or membrane-bound protein mobility. Traditionally, SPT is performed in two dimensions (2D) because of its technical simplicity. However, life occurs in three dimensions (3D) and many methods have been recently developed to track particles in 3D. Now, is the third dimension worth the effort? Here we investigate the differences between the 2D and 3D analyses of intracellular transport with the 3D development of a time-resolved mean square displacement (MSD) analysis introduced previously. The 3D trajectories, and the 2D projections, of fluorescent nanoparticles were obtained with an orbital tracking microscope in two different cell types: in Dictyostelium discoideum ameba and in adherent, more flattened HuH-7 human cells. As expected from the different 3D organization of both cells’ cytoskeletons, a third of the active transport was lost upon projection in the ameba whereas the identification of the active phases was barely affected in the HuH-7 cells. In both cell types, we found intracellular diffusion to be anisotropic and the diffusion coefficient values derived from the 2D analysis were therefore biased. (paper)

  5. Diffraction radiation from relativistic particles

    CERN Document Server

    Potylitsyn, Alexander Petrovich; Strikhanov, Mikhail Nikolaevich; Tishchenko, Alexey Alexandrovich

    2010-01-01

    This book deals with diffraction radiation, which implies the boundary problems of electromagnetic radiation theory. Diffraction radiation is generated when a charged particle moves in a vacuum near a target edge. Diffraction radiation of non-relativistic particles is widely used to design intense emitters in the cm wavelength range. Diffraction radiation from relativistic charged particles is important for noninvasive beam diagnostics and design of free electron lasers based on Smith-Purcell radiation which is diffraction radiation from periodic structures. Different analytical models of diffraction radiation and results of recent experimental studies are presented in this book. The book may also serve as guide to classical electrodynamics applications in beam physics and electrodynamics. It can be of great use for young researchers to develop skills and for experienced scientists to obtain new results.

  6. Diffraction radiation from relativistic particles

    International Nuclear Information System (INIS)

    Potylitsyn, Alexander Petrovich; Ryazanov, Mikhail Ivanovich; Strikhanov, Mikhail Nikolaevich; Tishchenko, Alexey Alexandrovich

    2010-01-01

    This book deals with diffraction radiation, which implies the boundary problems of electromagnetic radiation theory. Diffraction radiation is generated when a charged particle moves in a vacuum near a target edge. Diffraction radiation of non-relativistic particles is widely used to design intense emitters in the cm wavelength range. Diffraction radiation from relativistic charged particles is important for noninvasive beam diagnostics and design of free electron lasers based on Smith-Purcell radiation which is diffraction radiation from periodic structures. Different analytical models of diffraction radiation and results of recent experimental studies are presented in this book. The book may also serve as guide to classical electrodynamics applications in beam physics and electrodynamics. It can be of great use for young researchers to develop skills and for experienced scientists to obtain new results. (orig.)

  7. Laser vacuum acceleration of a relativistic electron bunch

    Energy Technology Data Exchange (ETDEWEB)

    Glazyrin, I V; Karpeev, A V; Kotova, O G; Nazarov, K S [E.I. Zababakhin All-Russian Scientific-Research Institute of Technical Physics, Russian Federal Nuclear Centre, Snezhinsk, Chelyabinsk region (Russian Federation); Bychenkov, V Yu [P N Lebedev Physics Institute, Russian Academy of Sciences, Moscow (Russian Federation)

    2015-06-30

    With regard to the problem of laser acceleration of a relativistic electron bunch we present a scheme of its vacuum acceleration directly by a relativistic intensity laser pulse. The energy of the electron bunch injected into the laser pulse leading edge increases during its coaxial movement to a thin, pulse-reflecting target. The laser-accelerated electrons continue to move free forward, passing through the target. The study of this acceleration scheme in the three-dimensional geometry is verified in a numerical simulation by the particle-in-cell method, which showed that the energy of a part of the electrons can increase significantly compared to the initial one. Restrictions are discussed, which impose limiting values of energy and total charge of accelerated electrons. (superstrong light fields)

  8. Particle Acceleration, Magnetic Field Generation in Relativistic Shocks

    Science.gov (United States)

    Nishikawa, Ken-Ichi; Hardee, P.; Hededal, C. B.; Richardson, G.; Sol, H.; Preece, R.; Fishman, G. J.

    2005-01-01

    Shock acceleration is an ubiquitous phenomenon in astrophysical plasmas. Plasma waves and their associated instabilities (e.g., the Buneman instability, two-streaming instability, and the Weibel instability) created in the shocks are responsible for particle (electron, positron, and ion) acceleration. Using a 3-D relativistic electromagnetic particle (REMP) code, we have investigated particle acceleration associated with a relativistic jet front propagating through an ambient plasma with and without initial magnetic fields. We find only small differences in the results between no ambient and weak ambient parallel magnetic fields. Simulations show that the Weibel instability created in the collisionless shock front accelerates particles perpendicular and parallel to the jet propagation direction. New simulations with an ambient perpendicular magnetic field show the strong interaction between the relativistic jet and the magnetic fields. The magnetic fields are piled up by the jet and the jet electrons are bent, which creates currents and displacement currents. At the nonlinear stage, the magnetic fields are reversed by the current and the reconnection may take place. Due to these dynamics the jet and ambient electron are strongly accelerated in both parallel and perpendicular directions.

  9. Particle-in-cell simulations of high energy electron production by intense laser pulses in underdense plasmas

    International Nuclear Information System (INIS)

    Susumu, Kato; Eisuke, Miura; Kazuyoshi, Koyama; Mitsumori, Tanimoto; Masahiro, Adachi

    2004-01-01

    The propagation of intense laser pulses and the generation of high energy electrons from underdense plasmas are investigated using two dimensional particle-in-cell simulations. When the ratio of the laser power to the critical power of relativistic self-focusing gets the optimal value, the laser pulse propagates in a steady way and electrons have maximum energies. (author)

  10. Particle-in-cell simulations of high energy electron production by intense laser pulses in underdense plasmas

    Energy Technology Data Exchange (ETDEWEB)

    Susumu, Kato; Eisuke, Miura; Kazuyoshi, Koyama [National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Ibaraki (Japan); Mitsumori, Tanimoto [Meisei Univ., Dept. of Electrical Engineering, Hino, Tokyo (Japan); Masahiro, Adachi [Hiroshima Univ., Graduate school of Advanced Science of Matter, Higashi-Hiroshima, Hiroshima (Japan)

    2004-07-01

    The propagation of intense laser pulses and the generation of high energy electrons from underdense plasmas are investigated using two dimensional particle-in-cell simulations. When the ratio of the laser power to the critical power of relativistic self-focusing gets the optimal value, the laser pulse propagates in a steady way and electrons have maximum energies. (author)

  11. Particle acceleration and injection problem in relativistic and nonrelativistic shocks

    International Nuclear Information System (INIS)

    Hoshino, M.

    2008-01-01

    Acceleration of charged particles at the collisionless shock is believed to be responsible for production of cosmic rays in a variety of astrophysical objects such as supernova, AGN jet, and GRB etc., and the diffusive shock acceleration model is widely accepted as a key process for generating cosmic rays with non-thermal, power-law energy spectrum. Yet it is not well understood how the collisionless shock can produce such high energy particles. Among several unresolved issues, two major problems are the so-called '' injection '' problem of the supra-thermal particles and the generation of plasma waves and turbulence in and around the shock front. With recent advance of computer simulations, however, it is now possible to discuss those issues together with dynamical evolution of the kinetic shock structure. A wealth of modern astrophysical observations also inspires the dynamical shock structure and acceleration processes along with the theoretical and computational studies on shock. In this presentation, we focus on the plasma wave generation and the associated particle energization that directly links to the injection problem by taking into account the kinetic plasma processes of both non-relativistic and relativistic shocks by using a particle-in-cell simulation. We will also discuss some new particle acceleration mechanisms such as stochastic surfing acceleration and wakefield acceleration by the action of nonlinear electrostatic fields. (author)

  12. Two-dimensional particle-in-cell simulation of the expansion of a plasma into a rarefied medium

    Energy Technology Data Exchange (ETDEWEB)

    Sarri, G; Quinn, K; Kourakis, I; Borghesi, M [Centre for Plasma Physics, The Queens University of Belfast, Belfast BT7 1NN (United Kingdom); Murphy, G C; Drury, L O C [Dublin Institute for Advanced Studies, 31 Fitzwilliam Place, Dublin 2 (Ireland); Dieckmann, M E; Ynnerman, A [Department of Science and Technology (ITN), Linkoeping University, 60174 Norrkoping (Sweden); Bret, A, E-mail: gsarri01@qub.ac.uk [ETSI Industriales, Universidad de Castilla-La Mancha, 13071 Ciudad Real (Spain)

    2011-07-15

    The expansion of a dense plasma through a more rarefied ionized medium has been studied by means of two-dimensional particle-in-cell simulations. The initial conditions involve a density jump by a factor of 100, located in the middle of an otherwise equally dense electron-proton plasma with uniform proton and electron temperatures of 10 eV and 1 keV, respectively. Simulations show the creation of a purely electrostatic collisionless shock together with an ion-acoustic soliton tied to its downstream region. The shock front is seen to evolve in filamentary structures consistently with the onset of the ion-ion instability. Meanwhile, an un-magnetized drift instability is triggered in the core part of the dense plasma. Such results explain recent experimental laser-plasma experiments, carried out in similar conditions, and are of intrinsic relevance to non-relativistic shock scenarios in the solar and astrophysical systems.

  13. Two-dimensional particle-in-cell simulation of the expansion of a plasma into a rarefied medium

    International Nuclear Information System (INIS)

    Sarri, G; Quinn, K; Kourakis, I; Borghesi, M; Murphy, G C; Drury, L O C; Dieckmann, M E; Ynnerman, A; Bret, A

    2011-01-01

    The expansion of a dense plasma through a more rarefied ionized medium has been studied by means of two-dimensional particle-in-cell simulations. The initial conditions involve a density jump by a factor of 100, located in the middle of an otherwise equally dense electron-proton plasma with uniform proton and electron temperatures of 10 eV and 1 keV, respectively. Simulations show the creation of a purely electrostatic collisionless shock together with an ion-acoustic soliton tied to its downstream region. The shock front is seen to evolve in filamentary structures consistently with the onset of the ion-ion instability. Meanwhile, an un-magnetized drift instability is triggered in the core part of the dense plasma. Such results explain recent experimental laser-plasma experiments, carried out in similar conditions, and are of intrinsic relevance to non-relativistic shock scenarios in the solar and astrophysical systems.

  14. Development of a relativistic Particle In Cell code PARTDYN for linear accelerator beam transport

    Energy Technology Data Exchange (ETDEWEB)

    Phadte, D., E-mail: deepraj@rrcat.gov.in [LPD, Raja Ramanna Centre for Advanced Technology, Indore 452013 (India); Patidar, C.B.; Pal, M.K. [MAASD, Raja Ramanna Centre for Advanced Technology, Indore (India)

    2017-04-11

    A relativistic Particle In Cell (PIC) code PARTDYN is developed for the beam dynamics simulation of z-continuous and bunched beams. The code is implemented in MATLAB using its MEX functionality which allows both ease of development as well higher performance similar to a compiled language like C. The beam dynamics calculations carried out by the code are compared with analytical results and with other well developed codes like PARMELA and BEAMPATH. The effect of finite number of simulation particles on the emittance growth of intense beams has been studied. Corrections to the RF cavity field expressions were incorporated in the code so that the fields could be calculated correctly. The deviations of the beam dynamics results between PARTDYN and BEAMPATH for a cavity driven in zero-mode have been discussed. The beam dynamics studies of the Low Energy Beam Transport (LEBT) using PARTDYN have been presented.

  15. Particle Interferometry for Relativistic Heavy-Ion Collisions

    CERN Document Server

    Wiedemann, Urs Achim; Wiedemann, Urs Achim; Heinz, Ulrich

    1999-01-01

    In this report we give a detailed account on Hanbury Brown/Twiss (HBT) particle interferometric methods for relativistic heavy-ion collisions. These exploit identical two-particle correlations to gain access to the space-time geometry and dynamics of the final freeze-out stage. The connection between the measured correlations in momentum space and the phase-space structure of the particle emitter is established, both with and without final state interactions. Suitable Gaussian parametrizations for the two-particle correlation function are derived and the physical interpretation of their parameters is explained. After reviewing various model studies, we show how a combined analysis of single- and two-particle spectra allows to reconstruct the final state of relativistic heavy-ion collisions.

  16. Three-dimensional spin-3 theories based on general kinematical algebras

    Energy Technology Data Exchange (ETDEWEB)

    Bergshoeff, Eric [Van Swinderen Institute for Particle Physics and Gravity, University of Groningen,Nijenborgh 4, 9747 AG Groningen (Netherlands); Grumiller, Daniel; Prohazka, Stefan [Institute for Theoretical Physics, TU Wien,Wiedner Hauptstrasse 8-10/136, A-1040 Vienna (Austria); Rosseel, Jan [Albert Einstein Center for Fundamental Physics, University of Bern,Sidlerstrasse 5, 3012 Bern (Switzerland); Faculty of Physics, University of Vienna,Boltzmanngasse 5, A-1090 Vienna (Austria)

    2017-01-25

    We initiate the study of non- and ultra-relativistic higher spin theories. For sake of simplicity we focus on the spin-3 case in three dimensions. We classify all kinematical algebras that can be obtained by all possible Inönü-Wigner contraction procedures of the kinematical algebra of spin-3 theory in three dimensional (anti-) de Sitter space-time. We demonstrate how to construct associated actions of Chern-Simons type, directly in the ultra-relativistic case and by suitable algebraic extensions in the non-relativistic case. We show how to give these kinematical algebras an infinite-dimensional lift by imposing suitable boundary conditions in a theory we call “Carroll Gravity”, whose asymptotic symmetry algebra turns out to be an infinite-dimensional extension of the Carroll algebra.

  17. Motion of the relativistic charged particle in an axisymmetric toroidal system

    Energy Technology Data Exchange (ETDEWEB)

    Chiyoda, K; Sugimoto, H [Electrotechnical Labs., Sakura, Ibaraki (Japan)

    1980-01-01

    The relativistic theory of motion of one particle by Morozov and Solov'ev is summarized for convenience of the present study. Then, a drift equation is given and four constants of motion, E/sub 0/, J perpendicular, J and J parallel, are obtained. These constants of motion are used in analyzing the particle motion in an axisymmetric toroidal system. The displacement of the particle from the magnetic surface, ..delta..r, and the period of the banana motion, tau, are obtained. The relativistic expressions of the displacement, ..delta..r, and the period, tau, are obtained by multiplying the corresponding nonrelativistic expressions by (1 - v parallel/sup 2//c/sup 2/) - 1/2, where the relativistic expression of ..delta..r includes the relativistic mass in terms of Larmor radius r/sub L/.

  18. THE EFFECT OF COOLING ON PARTICLE TRAJECTORIES AND ACCELERATION IN RELATIVISTIC MAGNETIC RECONNECTION

    Energy Technology Data Exchange (ETDEWEB)

    Kagan, Daniel; Nakar, Ehud [Raymond and Beverly Sackler School of Physics and Astronomy, Tel Aviv University, Tel Aviv 69978 (Israel); Piran, Tsvi, E-mail: daniel.kagan@mail.huji.ac.il [Racah Institute of Physics, The Hebrew University, Jerusalem 91904 (Israel)

    2016-12-20

    The maximum synchrotron burnoff limit of 160 MeV represents a fundamental limit to radiation resulting from electromagnetic particle acceleration in one-zone ideal plasmas. In magnetic reconnection, however, particle acceleration and radiation are decoupled because the electric field is larger than the magnetic field in the diffusion region. We carry out two-dimensional particle-in-cell simulations to determine the extent to which magnetic reconnection can produce synchrotron radiation above the burnoff limit. We use the test particle comparison (TPC) method to isolate the effects of cooling by comparing the trajectories and acceleration efficiencies of test particles incident on such a reconnection region with and without cooling them. We find that the cooled and uncooled particle trajectories are typically similar during acceleration in the reconnection region, and derive an effective limit on particle acceleration that is inversely proportional to the average magnetic field experienced by the particle during acceleration. Using the calculated distribution of this average magnetic field as a function of uncooled final particle energy, we find analytically that cooling does not affect power-law particle energy spectra except at energies far above the synchrotron burnoff limit. Finally, we compare fully cooled and uncooled simulations of reconnection, confirming that the synchrotron burnoff limit does not produce a cutoff in the particle energy spectrum. Our results indicate that the TPC method accurately predicts the effects of cooling on particle acceleration in relativistic reconnection, and that, even far above the burnoff limit, the synchrotron energy of radiation produced in reconnection is not limited by cooling.

  19. THE EFFECT OF COOLING ON PARTICLE TRAJECTORIES AND ACCELERATION IN RELATIVISTIC MAGNETIC RECONNECTION

    International Nuclear Information System (INIS)

    Kagan, Daniel; Nakar, Ehud; Piran, Tsvi

    2016-01-01

    The maximum synchrotron burnoff limit of 160 MeV represents a fundamental limit to radiation resulting from electromagnetic particle acceleration in one-zone ideal plasmas. In magnetic reconnection, however, particle acceleration and radiation are decoupled because the electric field is larger than the magnetic field in the diffusion region. We carry out two-dimensional particle-in-cell simulations to determine the extent to which magnetic reconnection can produce synchrotron radiation above the burnoff limit. We use the test particle comparison (TPC) method to isolate the effects of cooling by comparing the trajectories and acceleration efficiencies of test particles incident on such a reconnection region with and without cooling them. We find that the cooled and uncooled particle trajectories are typically similar during acceleration in the reconnection region, and derive an effective limit on particle acceleration that is inversely proportional to the average magnetic field experienced by the particle during acceleration. Using the calculated distribution of this average magnetic field as a function of uncooled final particle energy, we find analytically that cooling does not affect power-law particle energy spectra except at energies far above the synchrotron burnoff limit. Finally, we compare fully cooled and uncooled simulations of reconnection, confirming that the synchrotron burnoff limit does not produce a cutoff in the particle energy spectrum. Our results indicate that the TPC method accurately predicts the effects of cooling on particle acceleration in relativistic reconnection, and that, even far above the burnoff limit, the synchrotron energy of radiation produced in reconnection is not limited by cooling.

  20. A signed particle formulation of non-relativistic quantum mechanics

    Energy Technology Data Exchange (ETDEWEB)

    Sellier, Jean Michel, E-mail: jeanmichel.sellier@parallel.bas.bg

    2015-09-15

    A formulation of non-relativistic quantum mechanics in terms of Newtonian particles is presented in the shape of a set of three postulates. In this new theory, quantum systems are described by ensembles of signed particles which behave as field-less classical objects which carry a negative or positive sign and interact with an external potential by means of creation and annihilation events only. This approach is shown to be a generalization of the signed particle Wigner Monte Carlo method which reconstructs the time-dependent Wigner quasi-distribution function of a system and, therefore, the corresponding Schrödinger time-dependent wave-function. Its classical limit is discussed and a physical interpretation, based on experimental evidences coming from quantum tomography, is suggested. Moreover, in order to show the advantages brought by this novel formulation, a straightforward extension to relativistic effects is discussed. To conclude, quantum tunnelling numerical experiments are performed to show the validity of the suggested approach.

  1. Path integral for relativistic particle theory

    International Nuclear Information System (INIS)

    Fradkin, E.S.; Gitman, D.M.; Shvartsman, Sh.M.

    1990-06-01

    An action for a relativistic spinning particle interacting with external electromagnetic field is considered in reparametrization and local supergauge invariant form. It is shown that various path integral representations derived for the causal Green function correspond to the different forms of the relativistic particle action. The analogy of the path integral derived with the Lagrangian path integral of the field theory is discussed. It is shown that to obtain the causal propagator, the integration over the null mode of the Lagrangian multiplier corresponding to the reparametrization invariance, has to be performed in the (0,+infinity) limits. (author). 23 refs

  2. Relativistic quantum nonlocality for the three-qubit Greenberger-Horne-Zeilinger state

    International Nuclear Information System (INIS)

    Moradi, Shahpoor

    2008-01-01

    Lorentz transformation of the three-qubit Greenberger-Horne-Zeilinger (GHZ) state is studied. Also we obtain the relativistic spin joint measurement for the transformed state. Using these results it is shown that Bell's inequality is maximally violated for the three-qubit GHZ state in the relativistic regime. For ultrarelativistic particles we obtain the critical value for boost speed, which Bell's inequality is not violated for velocities smaller than this value. We also show that in the ultrarelativistic limit Bell's inequality is maximally violated for the GHZ state

  3. Particle Acceleration, Magnetic Field Generation and Emission from Relativistic Jets and Supernova Remnants

    Science.gov (United States)

    Nishikawa, K.-I.; Hartmann, D. H.; Hardee, P.; Hededal, C.; Mizunno, Y.; Fishman, G. J.

    2006-01-01

    We performed numerical simulations of particle acceleration, magnetic field generation, and emission from shocks in order to understand the observed emission from relativistic jets and supernova remnants. The investigation involves the study of collisionless shocks, where the Weibel instability is responsible for particle acceleration as well as magnetic field generation. A 3-D relativistic particle-in-cell (RPIC) code has been used to investigate the shock processes in electron-positron plasmas. The evolution of theWeibe1 instability and its associated magnetic field generation and particle acceleration are studied with two different jet velocities (0 = 2,5 - slow, fast) corresponding to either outflows in supernova remnants or relativistic jets, such as those found in AGNs and microquasars. Slow jets have intrinsically different structures in both the generated magnetic fields and the accelerated particle spectrum. In particular, the jet head has a very weak magnetic field and the ambient electrons are strongly accelerated and dragged by the jet particles. The simulation results exhibit jitter radiation from inhomogeneous magnetic fields, generated by the Weibel instability, which has different spectral properties than standard synchrotron emission in a homogeneous magnetic field.

  4. An energy principle for two-dimensional collisionless relativistic plasmas

    International Nuclear Information System (INIS)

    Otto, A.; Schindler, K.

    1984-01-01

    Using relativistic Vlasov theory an energy principle for two-dimensional plasmas is derived, which provides a sufficient and necessary criterion for the stability of relativistic plasma equilibria. This energy principle includes charge separating effects since the exact Poisson equation was taken into consideration. Applying the variational principle to the case of the relativistic plane plasma sheet, the same marginal wave length is found as in the non-relativistic case. (author)

  5. Particle Acceleration, Magnetic Field Generation, and Emission in Relativistic Pair Jets

    Science.gov (United States)

    Nishikawa, K.-I.; Ramirez-Ruiz, E.; Hardee, P.; Hededal, C.; Mizuno, Y.

    2005-01-01

    Shock acceleration is a ubiquitous phenomenon in astrophysical plasmas. Plasma waves and their associated instabilities (e.g., the Buneman instability, two-streaming instability, and the Weibel instability) created by relativistic pair jets are responsible for particle (electron, positron, and ion) acceleration. Using a 3-D relativistic electromagnetic particle (REMP) code, we have investigated particle acceleration associated with a relativistic jet propagating through an ambient plasma with and without initial magnetic fields. The growth rates of the Weibel instability depends on the distribution of pair jets. Simulations show that the Weibel instability created in the collisionless shock accelerates particles perpendicular and parallel to the jet propagation direction. The simulation results show that this instability is responsible for generating and amplifying highly nonuniform, small-scale magnetic fields, which contribute to the electron's transverse deflection behind the jet head. The "jitter" radiation from deflected electrons has different properties than synchrotron radiation which is calculated in a uniform magnetic field. This jitter radiation may be important to understanding the complex time evolution and/or spectral structure in gamma-ray bursts, relativistic jets, and supernova remnants.

  6. Relativistic extension of a charge-conservative finite element solver for time-dependent Maxwell-Vlasov equations

    Science.gov (United States)

    Na, D.-Y.; Moon, H.; Omelchenko, Y. A.; Teixeira, F. L.

    2018-01-01

    Accurate modeling of relativistic particle motion is essential for physical predictions in many problems involving vacuum electronic devices, particle accelerators, and relativistic plasmas. A local, explicit, and charge-conserving finite-element time-domain (FETD) particle-in-cell (PIC) algorithm for time-dependent (non-relativistic) Maxwell-Vlasov equations on irregular (unstructured) meshes was recently developed by Moon et al. [Comput. Phys. Commun. 194, 43 (2015); IEEE Trans. Plasma Sci. 44, 1353 (2016)]. Here, we extend this FETD-PIC algorithm to the relativistic regime by implementing and comparing three relativistic particle-pushers: (relativistic) Boris, Vay, and Higuera-Cary. We illustrate the application of the proposed relativistic FETD-PIC algorithm for the analysis of particle cyclotron motion at relativistic speeds, harmonic particle oscillation in the Lorentz-boosted frame, and relativistic Bernstein modes in magnetized charge-neutral (pair) plasmas.

  7. Quantum theory of relativistic charged particles in external fields

    International Nuclear Information System (INIS)

    Ruijsenaars, S.N.M.

    1976-01-01

    A study was made on external field theories in which the quantized field corresponds to relativistic elementary particles with non-zero rest mass. These particles are assumed to be charged, thus they have distinct antiparticles. The thesis consists of two parts. The first tries to accommodate the general features of theories of relativistic charged particles in external fields. Spin and dynamics in particular are not specified. In the second part, the results are applied to charged spin-1/2 and spin-0 particles, the dynamics of which are given by the Dirac resp. Klein-Gordon equation. The greater emphasis is on external fields which are rapidly decreasing, infinitely differentiable functions of space-time, but also considers time-independent fields. External fields, other than electromagnetic fields are also considered, e.g. scalar fields

  8. Two-dimensional approach to relativistic positioning systems

    International Nuclear Information System (INIS)

    Coll, Bartolome; Ferrando, Joan Josep; Morales, Juan Antonio

    2006-01-01

    A relativistic positioning system is a physical realization of a coordinate system consisting in four clocks in arbitrary motion broadcasting their proper times. The basic elements of the relativistic positioning systems are presented in the two-dimensional case. This simplified approach allows to explain and to analyze the properties and interest of these new systems. The positioning system defined by geodesic emitters in flat metric is developed in detail. The information that the data generated by a relativistic positioning system give on the space-time metric interval is analyzed, and the interest of these results in gravimetry is pointed out

  9. Relativistic mechanics of two interacting particles and bilocal theory

    International Nuclear Information System (INIS)

    Takabayasi, Takehiko

    1975-01-01

    New relativistic mechanics of two-particle system is set forth, where the two constituent particles are interacting by an arbitrary (central) action-at-a-distance. The fundamental equations are presented in a form covariant under general transformation of parameters parametrizing the world lines of constituent particles. The theory represents the proper relativistic generalization of the usual Newtonian mechanics in the sense that it tends in the non-relativistic (and weak interaction) limit to the usual mechanics of two particles moving under a corresponding non-relativistic potential. For the analysis of theory it is convenient to choose a certain particular gauge (i.e., parametrization) fixed by two gauge relations. This brings the theory to a canonical formalism accompanied by two weak equations, and in this gauge quantization can be performed. The result verifies that the relativistic quantum mechanics for two particles interacting by an action-at-a-distance is just represented by a bilocal wave equation and a subsidiary condition, with the clarification of its correspondence-theoretical foundation and internal dynamics. As an example the case of Hooke-type force is illustrated, where the internal motions are elliptic oscillations in the center-of-mass frame. Its quantum theory just reproduces the original form of bilocal theory giving bound states lying on a straightly rising trajectory and on its daughter trajectories. (auth.)

  10. Three-dimensional, three-component wall-PIV

    Science.gov (United States)

    Berthe, André; Kondermann, Daniel; Christensen, Carolyn; Goubergrits, Leonid; Garbe, Christoph; Affeld, Klaus; Kertzscher, Ulrich

    2010-06-01

    This paper describes a new time-resolved three-dimensional, three-component (3D-3C) measurement technique called wall-PIV. It was developed to assess near wall flow fields and shear rates near non-planar surfaces. The method is based on light absorption according to Beer-Lambert’s law. The fluid containing a molecular dye and seeded with buoyant particles is illuminated by a monochromatic, diffuse light. Due to the dye, the depth of view is limited to the near wall layer. The three-dimensional particle positions can be reconstructed by the intensities of the particle’s projection on an image sensor. The flow estimation is performed by a new algorithm, based on learned particle trajectories. Possible sources of measurement errors related to the wall-PIV technique are analyzed. The accuracy analysis was based on single particle experiments and a three-dimensional artificial data set simulating a rotating sphere.

  11. Classical and quantum dynamics of a kicked relativistic particle in a box

    Science.gov (United States)

    Yusupov, J. R.; Otajanov, D. M.; Eshniyazov, V. E.; Matrasulov, D. U.

    2018-03-01

    We study classical and quantum dynamics of a kicked relativistic particle confined in a one dimensional box. It is found that in classical case for chaotic motion the average kinetic energy grows in time, while for mixed regime the growth is suppressed. However, in case of regular motion energy fluctuates around certain value. Quantum dynamics is treated by solving the time-dependent Dirac equation with delta-kicking potential, whose exact solution is obtained for single kicking period. In quantum case, depending on the values of the kicking parameters, the average kinetic energy can be quasi periodic, or fluctuating around some value. Particle transport is studied by considering spatio-temporal evolution of the Gaussian wave packet and by analyzing the trembling motion.

  12. Three-dimensional particle image velocimetry in a generic can-type gas turbine combustor

    CSIR Research Space (South Africa)

    Meyers, BC

    2009-09-01

    Full Text Available The three-dimensional flow field inside a generic can-type, forward flow, experimental combustor was measured. A stereoscopic Particle Image Velocimetry (PIV) system was used to obtain the flow field of the combustor in the non-reacting condition...

  13. Auxiliary fields in the geometrical relativistic particle dynamics

    International Nuclear Information System (INIS)

    Amador, A; Bagatella, N; Rojas, E; Cordero, R

    2008-01-01

    We describe how to construct the dynamics of relativistic particles, following either timelike or null curves, by means of an auxiliary variables method instead of the standard theory of deformations for curves. There are interesting physical particle models governed by actions that involve higher order derivatives of the embedding functions of the worldline. We point out that the mechanical content of such models can be extracted wisely from a lower order action, which can be performed by implementing in the action a finite number of constraints that involve the geometrical relationship structures inherent to a curve and by using a covariant formalism. We emphasize our approach for null curves. For such systems, the natural time parameter is a pseudo-arclength whose properties resemble those of the standard proper time. We illustrate the formalism by applying it to some models for relativistic particles

  14. Auxiliary fields in the geometrical relativistic particle dynamics

    Energy Technology Data Exchange (ETDEWEB)

    Amador, A; Bagatella, N; Rojas, E [Departamento de Fisica, Facultad de Fisica e Inteligencia Artificial, Universidad Veracruzana, 91000 Xalapa, Veracruz (Mexico); Cordero, R [Departamento de Fisica, Escuela Superior de Fisica y Matematicas del I.P.N, Edificio 9, 07738 Mexico D.F (Mexico)], E-mail: aramador@gmail.com, E-mail: nbagatella@uv.mx, E-mail: cordero@esfm.ipn.mx, E-mail: efrojas@uv.mx

    2008-03-21

    We describe how to construct the dynamics of relativistic particles, following either timelike or null curves, by means of an auxiliary variables method instead of the standard theory of deformations for curves. There are interesting physical particle models governed by actions that involve higher order derivatives of the embedding functions of the worldline. We point out that the mechanical content of such models can be extracted wisely from a lower order action, which can be performed by implementing in the action a finite number of constraints that involve the geometrical relationship structures inherent to a curve and by using a covariant formalism. We emphasize our approach for null curves. For such systems, the natural time parameter is a pseudo-arclength whose properties resemble those of the standard proper time. We illustrate the formalism by applying it to some models for relativistic particles.

  15. Kinematics of a relativistic particle with de Sitter momentum space

    International Nuclear Information System (INIS)

    Arzano, Michele; Kowalski-Glikman, Jerzy

    2011-01-01

    We discuss kinematical properties of a free relativistic particle with deformed phase space in which momentum space is given by (a submanifold of) de Sitter space. We provide a detailed derivation of the action, Hamiltonian structure and equations of motion for such a free particle. We study the action of deformed relativistic symmetries on the phase space and derive explicit formulae for the action of the deformed Poincare group. Finally we provide a discussion on parametrization of the particle worldlines stressing analogies and differences with ordinary relativistic kinematics.

  16. Characterization of particle states in relativistic classical quantum theory

    International Nuclear Information System (INIS)

    Horwitz, L.P.; Rabin, Y.

    1977-02-01

    Classical and quantum relativistic mechanics are studied. The notion of a ''particle'' is defined in the classical case and the interpretation of mechanics in space-time is clarified. These notions are carried over to the quantum theory, as much as possible. The relation between the results of Feyman's path integral approach and the theory of Horwitz and Piron is discussed. The ''particle'' interpretation is shown to imply an asymptotic condition for scattering. A general method of constructing the dynamical mass spectrum of composite ''particle'' states is discussed. An interference experiment is proposed to affirm the interpretation and applicability of Stueckelberg type wave functions for actual physical phenomena. Some discussion of the relation of this relativistic quantum theory to Feynman's approach to quantum field theory is also given

  17. Self-assembly of three-dimensional open structures using patchy colloidal particles.

    Science.gov (United States)

    Rocklin, D Zeb; Mao, Xiaoming

    2014-10-14

    Open structures can display a number of unusual properties, including a negative Poisson's ratio, negative thermal expansion, and holographic elasticity, and have many interesting applications in engineering. However, it is a grand challenge to self-assemble open structures at the colloidal scale, where short-range interactions and low coordination number can leave them mechanically unstable. In this paper we discuss the self-assembly of three-dimensional open structures using triblock Janus particles, which have two large attractive patches that can form multiple bonds, separated by a band with purely hard-sphere repulsion. Such surface patterning leads to open structures that are stabilized by orientational entropy (in an order-by-disorder effect) and selected over close-packed structures by vibrational entropy. For different patch sizes the particles can form into either tetrahedral or octahedral structural motifs which then compose open lattices, including the pyrochlore, the hexagonal tetrastack and the perovskite lattices. Using an analytic theory, we examine the phase diagrams of these possible open and close-packed structures for triblock Janus particles and characterize the mechanical properties of these structures. Our theory leads to rational designs of particles for the self-assembly of three-dimensional colloidal structures that are possible using current experimental techniques.

  18. Canonical analysis of non-relativistic particle and superparticle

    Energy Technology Data Exchange (ETDEWEB)

    Kluson, Josef [Masaryk University, Department of Theoretical Physics and Astrophysics, Faculty of Science, Brno (Czech Republic)

    2018-02-15

    We perform canonical analysis of non-relativistic particle in Newton-Cartan Background. Then we extend this analysis to the case of non-relativistic superparticle in the same background. We determine constraints structure of this theory and find generator of κ-symmetry. (orig.)

  19. Interplanetary Magnetic Field Guiding Relativistic Particles

    Science.gov (United States)

    Masson, S.; Demoulin, P.; Dasso, S.; Klein, K. L.

    2011-01-01

    The origin and the propagation of relativistic solar particles (0.5 to few Ge V) in the interplanetary medium remains a debated topic. These relativistic particles, detected at the Earth by neutron monitors have been previously accelerated close to the Sun and are guided by the interplanetary magnetic field (IMF) lines, connecting the acceleration site and the Earth. Usually, the nominal Parker spiral is considered for ensuring the magnetic connection to the Earth. However, in most GLEs the IMF is highly disturbed, and the active regions associated to the GLEs are not always located close to the solar footprint of the nominal Parker spiral. A possible explanation is that relativistic particles are propagating in transient magnetic structures, such as Interplanetary Coronal Mass Ejections (ICMEs). In order to check this interpretation, we studied in detail the interplanetary medium where the particles propagate for 10 GLEs of the last solar cycle. Using the magnetic field and the plasma parameter measurements (ACE/MAG and ACE/SWEPAM), we found widely different IMF configurations. In an independent approach we develop and apply an improved method of the velocity dispersion analysis to energetic protons measured by SoHO/ERNE. We determined the effective path length and the solar release time of protons from these data and also combined them with the neutron monitor data. We found that in most of the GLEs, protons propagate in transient magnetic structures. Moreover, the comparison between the interplanetary magnetic structure and the interplanetary length suggest that the timing of particle arrival at Earth is dominantly determined by the type of IMF in which high energetic particles are propagating. Finally we find that these energetic protons are not significantly scattered during their transport to Earth.

  20. Arching in three-dimensional clogging

    Science.gov (United States)

    Török, János; Lévay, Sára; Szabó, Balázs; Somfai, Ellák; Wegner, Sandra; Stannarius, Ralf; Börzsönyi, Tamás

    2017-06-01

    Arching in dry granular material is a long established concept, however it remains still an open question how three-dimensional orifices clog. We investigate by means of numerical simulations and experimental data how the outflow creates a blocked configuration of particles. We define the concave surface of the clogged dome by two independent methods (geometric and density based). The average shape of the cupola for spheres is almost a hemisphere but individual samples have large holes in the structure indicating a blocked state composed of two-dimensional force chains rather than three-dimensional objects. The force chain structure justifies this assumption. For long particles the clogged configurations display large variations, and in certain cases the empty region reaches a height of 5 hole diameters. These structures involve vertical walls consisting of horizontally placed stable stacking of particles.

  1. Three-dimensional reconstruction of the giant mimivirus particle with an x-ray free-electron laser.

    Science.gov (United States)

    Ekeberg, Tomas; Svenda, Martin; Abergel, Chantal; Maia, Filipe R N C; Seltzer, Virginie; Claverie, Jean-Michel; Hantke, Max; Jönsson, Olof; Nettelblad, Carl; van der Schot, Gijs; Liang, Mengning; DePonte, Daniel P; Barty, Anton; Seibert, M Marvin; Iwan, Bianca; Andersson, Inger; Loh, N Duane; Martin, Andrew V; Chapman, Henry; Bostedt, Christoph; Bozek, John D; Ferguson, Ken R; Krzywinski, Jacek; Epp, Sascha W; Rolles, Daniel; Rudenko, Artem; Hartmann, Robert; Kimmel, Nils; Hajdu, Janos

    2015-03-06

    We present a proof-of-concept three-dimensional reconstruction of the giant mimivirus particle from experimentally measured diffraction patterns from an x-ray free-electron laser. Three-dimensional imaging requires the assembly of many two-dimensional patterns into an internally consistent Fourier volume. Since each particle is randomly oriented when exposed to the x-ray pulse, relative orientations have to be retrieved from the diffraction data alone. We achieve this with a modified version of the expand, maximize and compress algorithm and validate our result using new methods.

  2. Three-dimensional three-component particle velocimetry for microscale flows using volumetric scanning

    International Nuclear Information System (INIS)

    Klein, S A; Moran, J L; Posner, J D; Frakes, D H

    2012-01-01

    We present a diagnostic platform for measuring three-dimensional three-component (3D3C) velocity fields in microscopic volumes. The imaging system uses high-speed Nipkow spinning disk confocal microscopy. Confocal microscopy provides optical sectioning using pinhole spatial filtering which rejects light originating from out-of-focus objects. The system accomplishes volumetric scanning by rapid translation of the high numerical aperture objective using a piezo objective positioner. The motion of fluorescent microspheres is quantified using 3D3C super resolution particle-imaging velocimetry with instantaneous spatial resolutions of the order of 5 µm or less in all three dimensions. We examine 3D3C flow in a PDMS microchannel with an expanding section at 3D acquisition rates of 30 Hz, and find strong agreement with a computational model. Equations from the PIV and PTV literature adapted for a scanning objective provide estimates of maximum measurable velocity. The technique allows for isosurface visualization of 3D particle motion and robust high spatial resolution velocity measurements without requiring a calibration step or reconstruction algorithms. (paper)

  3. On free fall of a relativistic particle

    International Nuclear Information System (INIS)

    Chernikov, N.A.; Paramonova, N.N.; Shavokhina, N.S.

    2005-01-01

    The free fall of a relativistic particle is considered: the well-known fact of the light velocity constancy is taken into account in the Galilean problem about the movement of a particle from nongravitational forces and its fall onto the ground. The velocity hodograph and the world line of the particle are found

  4. Particle Acceleration, Magnetic Field Generation, and Emission in Relativistic Shocks

    Science.gov (United States)

    Nishikawa, Ken-IchiI.; Hededal, C.; Hardee, P.; Richardson, G.; Preece, R.; Sol, H.; Fishman, G.

    2004-01-01

    Shock acceleration is an ubiquitous phenomenon in astrophysical plasmas. Plasma waves and their associated instabilities (e.g., the Buneman instability, two-streaming instability, and the Weibel instability) created in the shocks are responsible for particle (electron, positron, and ion) acceleration. Using a 3-D relativistic electromagnetic particle (m) code, we have investigated particle acceleration associated with a relativistic jet front propagating through an ambient plasma with and without initial magnetic fields. We find only small differences in the results between no ambient and weak ambient parallel magnetic fields. Simulations show that the Weibel instability created in the collisionless shock front accelerates particles perpendicular and parallel to the jet propagation direction. New simulations with an ambient perpendicular magnetic field show the strong interaction between the relativistic jet and the magnetic fields. The magnetic fields are piled up by the jet and the jet electrons are bent, which creates currents and displacement currents. At the nonlinear stage, the magnetic fields are reversed by the current and the reconnection may take place. Due to these dynamics the jet and ambient electron are strongly accelerated in both parallel and perpendicular directions.

  5. Hybrid three-dimensional variation and particle filtering for nonlinear systems

    International Nuclear Information System (INIS)

    Leng Hong-Ze; Song Jun-Qiang

    2013-01-01

    This work addresses the problem of estimating the states of nonlinear dynamic systems with sparse observations. We present a hybrid three-dimensional variation (3DVar) and particle piltering (PF) method, which combines the advantages of 3DVar and particle-based filters. By minimizing the cost function, this approach will produce a better proposal distribution of the state. Afterwards the stochastic resampling step in standard PF can be avoided through a deterministic scheme. The simulation results show that the performance of the new method is superior to the traditional ensemble Kalman filtering (EnKF) and the standard PF, especially in highly nonlinear systems

  6. On the Relativistic Correction of Particles Trajectory in Tandem Type Electrostatic Accelerator

    Science.gov (United States)

    Minárik, Stanislav

    2015-08-01

    A constant potential is applied to the acceleration of the ion-beam in the tandem type electrostatic accelerator. However, not just one voltage is applied, but instead a number of applications can be made in succession by means of the tandem arrangement of high voltage tubes. This number of voltage applications, which is the number of so-called "stages" of a tandem accelerator, may be two, three, or four, depending on the chosen design. Electrostatic field with approximately constant intensity acts on ions in any stage. In general, non-relativistic dynamics is used for the description of the ion transport in tandem accelerator. Energies of accelerated ions are too low and relativistic effects cannot be commonly observed by standard experimental technique. Estimation of possible relativistic correction of ion trajectories is therefore only a matter of calculation. In this note, we briefly present such calculation. Our aim is to show how using the relativistic dynamics modifies the particles trajectory in tandem type accelerator and what parameters determine this modification.

  7. Continuation of full-scale three-dimensional numerical experiments on high-intensity particle and laser beam-matter interactions

    Energy Technology Data Exchange (ETDEWEB)

    Mori, Warren, B.

    2012-12-01

    We present results from the grant entitled, Continuation of full-scale three-dimensional numerical experiments on high-intensity particle and laser beam-matter interactions. The research significantly advanced the understanding of basic high-energy density science (HEDS) on ultra intense laser and particle beam plasma interactions. This advancement in understanding was then used to to aid in the quest to make 1 GeV to 500 GeV plasma based accelerator stages. The work blended basic research with three-dimensions fully nonlinear and fully kinetic simulations including full-scale modeling of ongoing or planned experiments. The primary tool was three-dimensional particle-in-cell simulations. The simulations provided a test bed for theoretical ideas and models as well as a method to guide experiments. The research also included careful benchmarking of codes against experiment. High-fidelity full-scale modeling provided a means to extrapolate parameters into regimes that were not accessible to current or near term experiments, thereby allowing concepts to be tested with confidence before tens to hundreds of millions of dollars were spent building facilities. The research allowed the development of a hierarchy of PIC codes and diagnostics that is one of the most advanced in the world.

  8. Relativistic corrections to one-particle neutron levels in the harmonic oscillator well

    International Nuclear Information System (INIS)

    Yanavichyus, A.I.

    1983-01-01

    Relativistic corrections to mass and potential energy for one-particle levels in the harmonic oscillator well are calculated in the first approximation of the perturbation theory. These corrections are, mainly negliqible, but they sharply increase with growth of the head and orbital quantum numbers. For the state 1s the relativistic correction is of the order of 0.01 MeV, and for 3p it is equal to 0.4 MeV. Thus, the relativistic correction for certain states approaches the energy of spin-orbital interactions and it should be taken into account in calculating the energy of one-particle levels

  9. Tailor-made three-dimensional hybrid scaffolds for cell cultures

    International Nuclear Information System (INIS)

    Psycharakis, Stylianos; Melissinaki, Vasileia; Giakoumaki, Anastasia; Ranella, Anthi; Tosca, Androniki

    2011-01-01

    The construction of the ideal three-dimensional scaffold for cell culture is one of the most intriguing topics in tissue engineering. It has been shown that cells can be cultured on most organic biomimetic materials, which now are losing popularity in favour of novel, hybrid systems. In this study, a series of photosensitive sol-gel hybrid materials, based on silicon-zirconium and silicon-titanium oxides, have been investigated for their suitability in three-dimensional scaffold fabrication. These materials can be structured by two-photon polymerization, a laser-based technique allowing the fabrication of micrometre-size structures with submicron resolution. The work presented here examined the effect of the organic/inorganic composition of the materials on cell behaviour and the establishment of a 'cell-culture friendly' environment. This is vital for cell adhesion, growth and differentiation, as the organic part of the material provides the soft matrix for cell growth, whereas the inorganic component gives the mechanical stability and rigidity of the three-dimensional structures. In addition, the use of femtosecond laser structuring permits the fabrication of a wide range of mechanically stable scaffolds of different sizes and shapes to be tested in terms of cell viability, proliferation and orientation.

  10. Relativistic and separable classical hamiltonian particle dynamics

    International Nuclear Information System (INIS)

    Sazdjian, H.

    1981-01-01

    We show within the Hamiltonian formalism the existence of classical relativistic mechanics of N scalar particles interacting at a distance which satisfies the requirements of Poincare invariance, separability, world-line invariance and Einstein causality. The line of approach which is adopted here uses the methods of the theory of systems with constraints applied to manifestly covariant systems of particles. The study is limited to the case of scalar interactions remaining weak in the whole phase space and vanishing at large space-like separation distances of the particles. Poincare invariance requires the inclusion of many-body, up to N-body, potentials. Separability requires the use of individual or two-body variables and the construction of the total interaction from basic two-body interactions. Position variables of the particles are constructed in terms of the canonical variables of the theory according to the world-line invariance condition and the subsidiary conditions of the non-relativistic limit and separability. Positivity constraints on the interaction masses squared of the particles ensure that the velocities of the latter remain always smaller than the velocity of light

  11. Hawking radiation of spin-1 particles from a three-dimensional rotating hairy black hole

    Energy Technology Data Exchange (ETDEWEB)

    Sakalli, I.; Ovgun, A., E-mail: ali.ovgun@emu.edu.tr [Eastern Mediterranean University Famagusta, North Cyprus, Department of Physics (Turkey)

    2015-09-15

    We study the Hawking radiation of spin-1 particles (so-called vector particles) from a three-dimensional rotating black hole with scalar hair using a Hamilton–Jacobi ansatz. Using the Proca equation in the WKB approximation, we obtain the tunneling spectrum of vector particles. We recover the standard Hawking temperature corresponding to the emission of these particles from a rotating black hole with scalar hair.

  12. Three-dimensional microbubble streaming flows

    Science.gov (United States)

    Rallabandi, Bhargav; Marin, Alvaro; Rossi, Massimiliano; Kaehler, Christian; Hilgenfeldt, Sascha

    2014-11-01

    Streaming due to acoustically excited bubbles has been used successfully for applications such as size-sorting, trapping and focusing of particles, as well as fluid mixing. Many of these applications involve the precise control of particle trajectories, typically achieved using cylindrical bubbles, which establish planar flows. Using astigmatic particle tracking velocimetry (APTV), we show that, while this two-dimensional picture is a useful description of the flow over short times, a systematic three-dimensional flow structure is evident over long time scales. We demonstrate that this long-time three-dimensional fluid motion can be understood through asymptotic theory, superimposing secondary axial flows (induced by boundary conditions at the device walls) onto the two-dimensional description. This leads to a general framework that describes three-dimensional flows in confined microstreaming systems, guiding the design of applications that profit from minimizing or maximizing these effects.

  13. Optical image encryption based on phase retrieval combined with three-dimensional particle-like distribution

    International Nuclear Information System (INIS)

    Chen, Wen; Chen, Xudong; Sheppard, Colin J R

    2012-01-01

    We propose a new phase retrieval algorithm for optical image encryption in three-dimensional (3D) space. The two-dimensional (2D) plaintext is considered as a series of particles distributed in 3D space, and an iterative phase retrieval algorithm is developed to encrypt the series of particles into phase-only masks. The feasibility and effectiveness of the proposed method are demonstrated by a numerical experiment, and the advantages and security of the proposed optical cryptosystems are also analyzed and discussed. (paper)

  14. Progress in three-particle scattering from LQCD

    Directory of Open Access Journals (Sweden)

    Briceño Raúl A.

    2017-01-01

    Full Text Available We present the status of our formalism for extracting three-particle scattering observables from lattice QCD (LQCD. The method relies on relating the discrete finitevolume energy spectrum of a quantum field theory with its scattering amplitudes. As the finite-volume spectrum can be directly determined in LQCD, this provides a method for determining scattering observables, and associated resonance properties, from the underlying theory. In a pair of papers published over the last two years, two of us have extended this approach to apply to relativistic three-particle scattering states. In this talk we summarize recent progress in checking and further extending this result. We describe an extension of the formalism to include systems in which two-to-three transitions can occur. We then present a check of the previously published formalism, in which we reproduce the known finite-volume energy shift of a three-particle bound state.

  15. Multi-Band Light Curves from Two-Dimensional Simulations of Gamma-Ray Burst Afterglows

    Science.gov (United States)

    MacFadyen, Andrew

    2010-01-01

    The dynamics of gamma-ray burst outflows is inherently multi-dimensional. 1.) We present high resolution two-dimensional relativistic hydrodynamics simulations of GRBs in the afterglow phase using adaptive mesh refinement (AMR). Using standard synchrotron radiation models, we compute multi-band light curves, from the radio to X-ray, directly from the 2D hydrodynamics simulation data. We will present on-axis light curves for both constant density and wind media. We will also present off-axis light curves relevant for searches for orphan afterglows. We find that jet breaks are smoothed due to both off-axis viewing and wind media effects. 2.) Non-thermal radiation mechanisms in GRB afterglows require substantial magnetic field strengths. In turbulence driven by shear instabilities in relativistic magnetized gas, we demonstrate that magnetic field is naturally amplified to half a percent of the total energy (epsilon B = 0.005). We will show high resolution three dimensional relativistic MHD simulations of this process as well as particle in cell (PIC) simulations of mildly relativistic collisionless shocks.

  16. Precursor Wave Emission Enhanced by Weibel Instability in Relativistic Shocks

    Science.gov (United States)

    Iwamoto, Masanori; Amano, Takanobu; Hoshino, Masahiro; Matsumoto, Yosuke

    2018-05-01

    We investigated the precursor wave emission efficiency in magnetized purely perpendicular relativistic shocks in pair plasmas. We extended our previous study to include the dependence of upstream magnetic field orientations. We performed two-dimensional particle-in-cell simulations and focused on two magnetic field orientations: the magnetic field in the simulation plane (i.e., in-plane configuration) and that perpendicular to the simulation plane (i.e., out-of-plane configuration). Our simulations in the in-plane configuration demonstrated that not only extraordinary but also ordinary mode waves are excited. We quantified the emission efficiency as a function of the magnetization parameter σ e and found that the large-amplitude precursor waves are emitted for a wide range of σ e . We found that especially at low σ e , the magnetic field generated by Weibel instability amplifies the ordinary mode wave power. The amplitude is large enough to perturb the upstream plasma, and transverse density filaments are generated as in the case of the out-of-plane configuration investigated in the previous study. We confirmed that our previous conclusion holds regardless of upstream magnetic field orientations with respect to the two-dimensional simulation plane. We discuss the precursor wave emission in three dimensions and the feasibility of wakefield acceleration in relativistic shocks based on our results.

  17. On the size distribution of one-, two- and three-dimensional Voronoi cells

    International Nuclear Information System (INIS)

    Marthinsen, K.

    1994-03-01

    The present report gives a presentation of the different cell size distribution obtained by computer simulations of random Voronoi cell structures in one-, two- and three-dimensional space. The random Voronoi cells are constructed from cell centroids randomly distributed along a string, in the plane and in three-dimensional space, respectively. The size distributions are based on 2-3 · 10 4 cells. For the spacial polyhedra both the distribution of volumes, areas and radii are presented, and the two latter quantities are compared to the distributions of areas and radii from a planar section through the three-dimensional structure as well as to the corresponding distributions obtained from a pure two-dimensional cell structure. 11 refs., 11 figs

  18. Three-dimensional Kinetic Pulsar Magnetosphere Models: Connecting to Gamma-Ray Observations

    Science.gov (United States)

    Kalapotharakos, Constantinos; Brambilla, Gabriele; Timokhin, Andrey; Harding, Alice K.; Kazanas, Demosthenes

    2018-04-01

    We present three-dimensional (3D) global kinetic pulsar magnetosphere models, where the charged particle trajectories and the corresponding electromagnetic fields are treated self-consistently. For our study, we have developed a Cartesian 3D relativistic particle-in-cell code that incorporates radiation reaction forces. We describe our code and discuss the related technical issues, treatments, and assumptions. Injecting particles up to large distances in the magnetosphere, we apply arbitrarily low to high particle injection rates, and obtain an entire spectrum of solutions from close to the vacuum-retarded dipole to close to the force-free (FF) solution, respectively. For high particle injection rates (close to FF solutions), significant accelerating electric field components are confined only near the equatorial current sheet outside the light cylinder. A judicious interpretation of our models allows the particle emission to be calculated, and consequently, the corresponding realistic high-energy sky maps and spectra to be derived. Using model parameters that cover the entire range of spin-down powers of Fermi young and millisecond pulsars, we compare the corresponding model γ-ray light curves, cutoff energies, and total γ-ray luminosities with those observed by Fermi to discover a dependence of the particle injection rate, { \\mathcal F }, on the spin-down power, \\dot{{ \\mathcal E }}, indicating an increase of { \\mathcal F } with \\dot{{ \\mathcal E }}. Our models, guided by Fermi observations, provide field structures and particle distributions that are not only consistent with each other but also able to reproduce a broad range of the observed γ-ray phenomenologies of both young and millisecond pulsars.

  19. Non-relativistic model of two-particle decay

    International Nuclear Information System (INIS)

    Dittrich, J.; Exner, P.

    1986-01-01

    A simple non-relativistic model of a spinless particle decaying into two lighter particles is treated in detail. It is similar to the Lee-model description of V-particle decay. Galilean covariance is formulated properly, by means of a unitary projective representation acting on the state space of the model. After separating the centre-of-mass motion the meromorphic structure of the reduced resolvent is deduced

  20. On the confinement of a Dirac particle to a two-dimensional ring

    International Nuclear Information System (INIS)

    Bakke, K.; Furtado, C.

    2012-01-01

    In this contribution, we propose a new model for studying the confinement of a spin-half particle to a two-dimensional quantum ring for systems described by the Dirac equation by introducing a new coupling into the Dirac equation. We show that the introduction of this new coupling into the Dirac equation yields a generalization of the two-dimensional quantum ring model proposed by Tan and Inkson [W.-C. Tan, J.C. Inkson, Semicond. Sci. Technol. 11 (1996) 1635] for relativistic spin-half quantum particles. -- Highlights: ► Two-dimensional ring model for condensed matter systems described by the Dirac equation. ► Exact solutions of the Dirac equation. ► Persistent currents for Dirac-like systems confined to a two-dimensional quantum ring.

  1. Relativistic motion of spinning particles in a gravitational field

    International Nuclear Information System (INIS)

    Chicone, C.; Mashhoon, B.; Punsly, B.

    2005-01-01

    The relative motion of a classical relativistic spinning test particle is studied with respect to a nearby free test particle in the gravitational field of a rotating source. The effects of the spin-curvature coupling force are elucidated and the implications of the results for the motion of rotating plasma clumps in astrophysical jets are discussed

  2. Tailor-made three-dimensional hybrid scaffolds for cell cultures

    Energy Technology Data Exchange (ETDEWEB)

    Psycharakis, Stylianos; Melissinaki, Vasileia; Giakoumaki, Anastasia; Ranella, Anthi [Institute of Electronic Structure and Laser, Foundation for Research and Technology Hellas, PO Box 1527, 711 10 Heraklion, Crete (Greece); Tosca, Androniki, E-mail: ranthi@iesl.forth.gr [Department of Medicine, University of Crete, 710 03 Heraklion, Crete (Greece)

    2011-08-15

    The construction of the ideal three-dimensional scaffold for cell culture is one of the most intriguing topics in tissue engineering. It has been shown that cells can be cultured on most organic biomimetic materials, which now are losing popularity in favour of novel, hybrid systems. In this study, a series of photosensitive sol-gel hybrid materials, based on silicon-zirconium and silicon-titanium oxides, have been investigated for their suitability in three-dimensional scaffold fabrication. These materials can be structured by two-photon polymerization, a laser-based technique allowing the fabrication of micrometre-size structures with submicron resolution. The work presented here examined the effect of the organic/inorganic composition of the materials on cell behaviour and the establishment of a 'cell-culture friendly' environment. This is vital for cell adhesion, growth and differentiation, as the organic part of the material provides the soft matrix for cell growth, whereas the inorganic component gives the mechanical stability and rigidity of the three-dimensional structures. In addition, the use of femtosecond laser structuring permits the fabrication of a wide range of mechanically stable scaffolds of different sizes and shapes to be tested in terms of cell viability, proliferation and orientation.

  3. Relativistic band gaps in one-dimensional disordered systems

    International Nuclear Information System (INIS)

    Clerk, G.J.; McKellar, B.H.J.

    1992-01-01

    Conditions for the existence of band gaps in a one-dimensional disordered array of δ-function potentials possessing short range order are developed in a relativistic framework. Both Lorentz vector and scalar type potentials are treated. The relationship between the energy gaps and the transmission properties of the array are also discussed. 20 refs., 2 figs

  4. Frame dependence of world lines for directly interacting classical relativistic particles

    International Nuclear Information System (INIS)

    Molotkov, V.V.; Todorov, I.T.

    1979-06-01

    The motion of world lines is studied in the constraint Hamiltonian formulation of relativistic point particle dynamics. The particle world lines are shown to depend, in general (in the presence of interaction) on the choice of the equal time hyperplane (the only exception being the elastic scattering of rigid balls). However, the relative motion of a 2-particle system and the (classical) S-matrix are independent of this choice. This inferred that particle trajectories should not be regarded as frame independent observables in the classical theory of relativistic particles. (author)

  5. Description of width and spectra of two relativistic fermions bound states

    International Nuclear Information System (INIS)

    Sidorov, A.V.; Skachkov, N.B.

    1979-01-01

    The formalism for relativistic description of two particles with spin 1/2 is constructed. Used is the two-particle three-dimensional equation, obtained by quasipotential approach. Quasipotential equation in the relativistic configurational space with OBEP potential is reduced to the system of partial equations which is the analog of nonrelativistic Hamada-Jonston system. WKB approach is used to calculate mass spectra and leptonic width of mesons in quark model. The results of the study can be applied to the calculation of mass spectra and widths of electromagnetic decays of systems of e + e - , μ + μ - , c anti c, b anti b, N anti N type

  6. Three-dimensional particle tracking velocimetry using dynamic vision sensors

    Science.gov (United States)

    Borer, D.; Delbruck, T.; Rösgen, T.

    2017-12-01

    A fast-flow visualization method is presented based on tracking neutrally buoyant soap bubbles with a set of neuromorphic cameras. The "dynamic vision sensors" register only the changes in brightness with very low latency, capturing fast processes at a low data rate. The data consist of a stream of asynchronous events, each encoding the corresponding pixel position, the time instant of the event and the sign of the change in logarithmic intensity. The work uses three such synchronized cameras to perform 3D particle tracking in a medium sized wind tunnel. The data analysis relies on Kalman filters to associate the asynchronous events with individual tracers and to reconstruct the three-dimensional path and velocity based on calibrated sensor information.

  7. Classical testing particles and (4 + N)-dimensional theories of space-time

    International Nuclear Information System (INIS)

    Nieto-Garcia, J.A.

    1986-01-01

    The Lagrangian theory of a classical relativistic spinning test particle (top) developed by Hanson and Regge and by Hojman is briefly reviewed. Special attention is devoted to the constraints imposed on the dynamical variables associated with the system of this theory. The equations for a relativistic top are formulated in a way suitable for use in the study of geometrical properties of the 4 + N-dimensional Kaluza-Klein background. It is shown that the equations of motion of a top in five dimensions reduce to the Hanson-Regge generalization of the Bargmann-Michel-Telegdi equations of motion in four dimensions when suitable conditions on the spin tensor are imposed. The classical bosonic relativistic string theory is discussed and the connection of this theory with the top theory is examined. It is found that the relation between the string and the top leads naturally to the consideration of a 3-dimensional extended system (called terron) which sweeps out a 4-dimensional surface as it evolves in a space-time. By using a square root procedure based on ideas by Teitelboim a theory of a supersymmetric top is developed. The quantization of the new supersymmetric system is discussed. Conclusions and suggestions for further research are given

  8. Note of positions of particles in classical relativistic mechanics

    International Nuclear Information System (INIS)

    Pazma, V.

    1983-01-01

    The relation between world-lines and the position vector of a particle is studied from the point of view of gauge system theory. The expressions for the position vector of a free relativistic particle and of two interacting particles described by the Todorov-Komar model are derived under plausible assumptions. The relation between the physical meaning of basic canonical variables and the choice of a gauge is also discussed. (author)

  9. Three-dimensional epithelial tissues generated from human embryonic stem cells.

    Science.gov (United States)

    Hewitt, Kyle J; Shamis, Yulia; Carlson, Mark W; Aberdam, Edith; Aberdam, Daniel; Garlick, Jonathan A

    2009-11-01

    The use of pluripotent human embryonic stem (hES) cells for tissue engineering may provide advantages over traditional sources of progenitor cells because of their ability to give rise to multiple cell types and their unlimited expansion potential. We derived cell populations with properties of ectodermal and mesenchymal cells in two-dimensional culture and incorporated these divergent cell populations into three-dimensional (3D) epithelial tissues. When grown in specific media and substrate conditions, two-dimensional cultures were enriched in cells (EDK1) with mesenchymal morphology and surface markers. Cells with a distinct epithelial morphology (HDE1) that expressed cytokeratin 12 and beta-catenin at cell junctions became the predominant cell type when EDK1 were grown on surfaces enriched in keratinocyte-derived extracellular matrix proteins. When these cells were incorporated into the stromal and epithelial tissue compartments of 3D tissues, they generated multilayer epithelia similar to those generated with foreskin-derived epithelium and fibroblasts. Three-dimensional tissues demonstrated stromal cells with morphologic features of mature fibroblasts, type IV collagen deposition in the basement membrane, and a stratified epithelium that expressed cytokeratin 12. By deriving two distinct cell lineages from a common hES cell source to fabricate complex tissues, it is possible to explore environmental cues that will direct hES-derived cells toward optimal tissue form and function.

  10. A relativistic gauge model describing N particles bound by harmonic forces

    International Nuclear Information System (INIS)

    Filippov, A.T.

    1987-01-01

    Application of the principle of gauging to linear canonical symmetries of simplest/rudimentary/bilinear lagrangians is shown to produce a relativistic version of the Lagrangian describing N particles bound by harmonic forces. For pairwise coupled identical particles the gauge group is T 1 xU 1 , xSU N-1 . A model for the relativistic discrete string (a chain of N particles) is also discussed. All these gauge theoried of particles can be quantized by standard methods

  11. COLLISIONLESS ELECTRON–ION SHOCKS IN RELATIVISTIC UNMAGNETIZED JET–AMBIENT INTERACTIONS: NON-THERMAL ELECTRON INJECTION BY DOUBLE LAYER

    International Nuclear Information System (INIS)

    Ardaneh, Kazem; Cai, Dongsheng; Nishikawa, Ken-Ichi

    2016-01-01

    The course of non-thermal electron ejection in relativistic unmagnetized electron–ion shocks is investigated by performing self-consistent particle-in-cell simulations. The shocks are excited through the injection of a relativistic jet into ambient plasma, leading to two distinct shocks (referred to as the trailing shock and leading shock) and a contact discontinuity. The Weibel-like instabilities heat the electrons up to approximately half of the ion kinetic energy. The double layers formed in the trailing and leading edges then accelerate the electrons up to the ion kinetic energy. The electron distribution function in the leading edge shows a clear, non-thermal power-law tail which contains ∼1% of electrons and ∼8% of the electron energy. Its power-law index is −2.6. The acceleration efficiency is ∼23% by number and ∼50% by energy, and the power-law index is −1.8 for the electron distribution function in the trailing edge. The effect of the dimensionality is examined by comparing the results of three-dimensional simulations with those of two-dimensional simulations. The comparison demonstrates that electron acceleration is more efficient in two dimensions.

  12. Larmor precession and dwell time of a relativistic particle scattered by a rectangular quantum well

    CERN Document Server

    Li, Z J; Liang, J J; Liang, J Q

    2003-01-01

    The Larmor precession of a relativistic neutral spin particle in a uniform constant magnetic field confined to the region of a one-dimensional rectangular potential well is investigated. The spin precession serves as a clock to measure the time spent by a quantum particle dwelling at a potential well. With the help of a general spin coherent state it is explicitly shown that the spin precession time is equal to the dwell time in the first-order approximation of the infinitesimal field limit. The comparison of the time in a potential well with that in free space shows apparent superluminality.

  13. Real-time energy detector for relativistic charged particles

    International Nuclear Information System (INIS)

    Piestrup, A.

    1988-01-01

    The objective of the research is to investigate the use of coherent transition radiation to measure the energy of ultra-relativistic charged particles. The research has possible applications for the detection and identification of these particles. It can also be used for beam diagnostics for both high-repetition-rate and single-pulse, high-current accelerators. The device is low cost and can operate in situ while causing little or no perturbation to the beam. Three such coherent radiators have been constructed and tested at two accelerators using electron beam energies ranging from 50 to 228 MeV. Soft x-ray emission (1 keV to 4 keV) was emitted in a circularly symmetrical annulus with half-angle divergence of 2.5 to 9.0 mr. By selecting foil thickness and spacing, it is possible to design radiators whose angle of emission varies radically over a range of charge-particle energies

  14. Mechanism of 238U disintegration induced by relativistic particles

    International Nuclear Information System (INIS)

    Andronenko, L.N.; Zhdanov, A.A.; Kravtsov, A.V.; Solyakin, G.E.

    2002-01-01

    In heavy-nucleus disintegration induced by a relativistic projectile particle, the production of collinear massive fragments accompanied by numerous charged particles and neutrons is explained in terms of the mechanism of projectile-momentum compensation due to the emission of a particle whose mass is greater than the projectile mass

  15. Particle-production mechanism in relativistic heavy-ion collisions

    International Nuclear Information System (INIS)

    Bush, B.W.; Nix, J.R.

    1994-01-01

    We discuss the production of particles in relativistic heavy-ion collisions through the mechanism of massive bremsstrahlung, in which massive mesons are emitted during rapid nucleon acceleration. This mechanism is described within the framework of classical hadrodynamics for extended nucleons, corresponding to nucleons of finite size interacting with massive meson fields. This new theory provides a natural covariant microscopic approach to relativistic heavy-ion collisions that includes automatically spacetime nonlocality and retardation, nonequilibrium phenomena, interactions among all nucleons, and particle production. Inclusion of the finite nucleon size cures the difficulties with preacceleration and runaway solutions that have plagued the classical theory of self-interacting point particles. For the soft reactions that dominate nucleon-nucleon collisions, a significant fraction of the incident center-of-mass energy is radiated through massive bremsstrahlung. In the present version of the theory, this radiated energy is in the form of neutral scalar (σ) and neutral vector (ω) mesons, which subsequently decay primarily into pions with some photons also. Additional meson fields that are known to be important from nucleon-nucleon scattering experiments should be incorporated in the future, in which case the radiated energy would also contain isovector pseudoscalar (π + , π - , π 0 ), isovector scalar (δ + , δ - , δ 0 ), isovector vector (ρ + , ρ - , ρ 0 ), and neutral pseudoscalar (η) mesons

  16. Three-dimensional analysis of nonlinear plasma oscillation

    International Nuclear Information System (INIS)

    Miano, G.

    1990-01-01

    In an underdense plasma a large-amplitude plasma oscillation may be produced by the beating of two external and colinear electromagnetic waves with a frequency difference approximately equal to the plasma frequency - plasma beat wave (PBW) resonant mechanism. The plasma oscillations are driven by the ponderomotive force arising from the beating of the two imposed electromagnetic waves. In this paper two pump electromagnetic waves with arbitrary transverse profiles have been considered. The plasma is described by using the three dimensinal weakly relativistic fluid equations. The nonlinear plasma oscillation dynamics is studied by using the eulerian description, the averaging and the multiple time scale methods. Unlike the linear theory a strong cross field coupling between longitudinal ans transverse electric field components of the plasma oscillation comes out, resulting in a nonlinear phase change and energy transfer between the two components. Unlike the one-dimensional nonlinear theory, the nonlinear frequency shift is caused by relativistic effects as well as by convective effects and electromagnetic field generated from the three dimensional plasma oscillation. The large amplitude plasma oscillation dynamics produced by a bunched relativistic electron beam with arbitrary transverse profile - plasma wave field (PWF) - or by a high power single frequency short electromagnetic pulse with arbitrary transverse profile - electromagnetic plasma wake field (EPWF) - may be described by means of the present theory. (orig.)

  17. Dynamical properties for the problem of a particle in an electric field of wave packet: Low velocity and relativistic approach

    Energy Technology Data Exchange (ETDEWEB)

    Oliveira, Diego F.M., E-mail: diegofregolente@gmail.com [Institute for Multiscale Simulations, Friedrich-Alexander Universität, D-91052, Erlangen (Germany); Leonel, Edson D., E-mail: edleonel@rc.unesp.br [Departamento de Estatística, Matemática Aplicada e Computação, UNESP, Univ. Estadual Paulista, Av. 24A, 1515, Bela Vista, 13506-900, Rio Claro, SP (Brazil); Departamento de Física, UNESP, Univ. Estadual Paulista, Av. 24A, 1515, 13506-900, Rio Claro, SP (Brazil)

    2012-11-01

    We study some dynamical properties for the problem of a charged particle in an electric field considering both the low velocity and relativistic cases. The dynamics for both approaches is described in terms of a two-dimensional and nonlinear mapping. The structure of the phase spaces is mixed and we introduce a hole in the chaotic sea to let the particles to escape. By changing the size of the hole we show that the survival probability decays exponentially for both cases. Additionally, we show for the relativistic dynamics, that the introduction of dissipation changes the mixed phase space and attractors appear. We study the parameter space by using the Lyapunov exponent and the average energy over the orbit and show that the system has a very rich structure with infinite family of self-similar shrimp shaped embedded in a chaotic region.

  18. Relativistic motion of particle in photogravitational field of star

    International Nuclear Information System (INIS)

    Zubko, O.L.

    2014-01-01

    Relativistic motion of particle in photogravitational field of star has been considered at different levels. It is shown that taking into account direct light pressure, elliptical orbit of the particle increases in sizes. Taking into account longitudinal Doppler effect and aberration of light leads to the motion of the particle by decreasing in size ellipse, which also has decreasing and eccentricity. Taking into account forces proportional to v 1 2 /c 2 leads to a faster reduction of the ellipse and its eccentricity. (authors)

  19. Particle Acceleration, Magnetic Field Generation and Emission from Relativistic Jets

    Science.gov (United States)

    Nishikawa, K.-I.; Hardee, P.; Hededal, C.; Mizuno, Yosuke; Fishman, G. Jerry; Hartmann, D. H.

    2006-01-01

    Nonthermal radiation observed from astrophysical systems containing relativistic jets and shocks, e.g., active galactic nuclei (AGNs), gamma-ray bursts (GRBs), supernova remnants, and Galactic microquasar systems usually have power-law emission spectra. Fermi acceleration is the mechanism usually assumed for the acceleration of particles in astrophysical environments. Recent PIC simulations using injected relativistic electron-ion (electro-positron) jets show that particle acceleration occurs within the downstream jet, rather than by the scattering of particles back and forth across the shock as in Fermi acceleration. Shock acceleration' is a ubiquitous phenomenon in astrophysical plasmas. Plasma waves and their associated instabilities (e.g., the Buneman instability, other two-streaming instability, and the Weibel instability) created in the shocks are responsible for particle (electron, positron, and ion) acceleration. The simulation results show that the Weibel instability is responsible for generating and amplifying highly nonuniform, small-scale magnetic fields. These magnetic fields contribute to the electron's transverse deflection behind the jet head. The "jitter" radiation from deflected electrons has different spectral properties than synchrotron radiation which is calculated in a uniform magnetic field. This jitter radiation may be important to understanding the complex time evolution and/or spectral structure in gamma-ray bursts, relativistic jets, and supernova remnants. We will review recent PIC simulations of relativistic jets and try to make a connection with observations.

  20. The front form of relativistic Lagrangian dynamics in the two-dimensional space-time and its connection with the Hamiltonian description

    International Nuclear Information System (INIS)

    Sokolov, S.N.; Tret'yak, V.I.

    1985-01-01

    The Lagrangian relativistic theory in the two-dimensional space-time in the front form of dynamics is formulated and its connections with the predictive mechanics, with the Hamiltonian description, and with the Fokker-type action theory are established. The relations are found in a closed form without using formal expansions. The existence of mathematical limitations on a magnitude of Lagrangians of two-particle interactions is shown

  1. Quantifying the mechanical micro-environment during three-dimensional cell expansion on microbeads by means of individual cell-based modelling.

    Science.gov (United States)

    Smeets, Bart; Odenthal, Tim; Tijskens, Engelbert; Ramon, Herman; Van Oosterwyck, Hans

    2013-10-01

    Controlled in vitro three-dimensional cell expansion requires culture conditions that optimise the biophysical micro-environment of the cells during proliferation. In this study, we propose an individual cell-based modelling platform for simulating the mechanics of cell expansion on microcarriers. The lattice-free, particle-based method considers cells as individual interacting particles that deform and move over time. The model quantifies how the mechanical micro-environment of individual cells changes during the time of confluency. A sensitivity analysis is performed, which shows that changes in the cell-specific properties of cell-cell adhesion and cell stiffness cause the strongest change in the mechanical micro-environment of the cells. Furthermore, the influence of the mechanical properties of cells and microbead is characterised. The mechanical micro-environment is strongly influenced by the adhesive properties and the size of the microbead. Simulations show that even in the absence of strong biological heterogeneity, a large heterogeneity in mechanical stresses can be expected purely due to geometric properties of the culture system.

  2. Two-spinor description of massive particles and relativistic spin projection operators

    Science.gov (United States)

    Isaev, A. P.; Podoinitsyn, M. A.

    2018-04-01

    On the basis of the Wigner unitary representations of the covering group ISL (2 , C) of the Poincaré group, we obtain spin-tensor wave functions of free massive particles with arbitrary spin. The wave functions automatically satisfy the Dirac-Pauli-Fierz equations. In the framework of the two-spinor formalism we construct spin-vectors of polarizations and obtain conditions that fix the corresponding relativistic spin projection operators (Behrends-Fronsdal projection operators). With the help of these conditions we find explicit expressions for relativistic spin projection operators for integer spins (Behrends-Fronsdal projection operators) and then find relativistic spin projection operators for half integer spins. These projection operators determine the numerators in the propagators of fields of relativistic particles. We deduce generalizations of the Behrends-Fronsdal projection operators for arbitrary space-time dimensions D > 2.

  3. Self-consistent Analysis of Three-dimensional Uniformly Charged Ellipsoid with Zero Emittance

    International Nuclear Information System (INIS)

    Batygin, Yuri K.

    2001-01-01

    A self-consistent treatment of a three-dimensional ellipsoid with negligible emittance in time-dependent external field is performed. Envelope equations describing the evolution of an ellipsoid boundary are discussed. For a complete model it is required that the initial particle momenta be a linear function of the coordinates. Numerical example and verification of the problem by a 3-dimensional particle-in-cell simulations are given

  4. On the relativistic quantum mechanics of two interacting spinless particles

    International Nuclear Information System (INIS)

    Rizov, V.A.; Sazdjian, H.; Todorov, I.T.

    1984-05-01

    The L 2 -scalar product ∫ PHI*(x)PSI(x) d 3 x is not appropriate for the space of states describing the center-of-mass relative motion of two relativistic particles whose interaction is given by an energy dependent quasipotential. The problem already appears in the relativistic quantum mechanics of a Klein-Gordon charged particle in an external field. We extend the methods developed for that case to study a two-particle system with an energy independent scalar interaction as well as the relativistic Coulomb problem. We write down a Poincare invariant inner product for which the eigenfunctions corresponding to different energy eigenvalues are orthogonal. We also construct a perturbative expansion for bound-state energy eigenvalues corresponding to an arbitrary energy dependent (quasipotential) correction to an unperturbed Hamiltonian with a known spectrum. The description of observables and transition probabilities for eigenvalue problems with a polynomial dependence on the spectral parameter is also discussed

  5. A physiologic three-dimensional cell culture system to investigate the role of decorin in matrix organisation and cell survival

    International Nuclear Information System (INIS)

    Seidler, Daniela G.; Schaefer, Liliana; Robenek, Horst; Iozzo, Renato V.; Kresse, Hans; Schoenherr, Elke

    2005-01-01

    In vivo cells exist in a three-dimensional environment generated and maintained by multiple cell-cell and cell-matrix interactions. Proteoglycans, like decorin, affect these complex interactions. Thus, we sought to investigate the role of decorin in a three-dimensional environment where the matrix was generated over time by decorin-deficient fibroblasts in the presence of L-ascorbic acid 2-phosphate. The cells were viable and proliferated in response to FGF2. Decorin was incorporated in the matrix and caused a ∼2 nm shift in the average diameter of the collagen fibrils, and the range and distribution of the fibrils became narrower and more uniform. Although there were no appreciable changes in collagen composition, we found that exogenous decorin induced the de novo synthesis of collagen I and V and cross-linked β (I). In the early phases of the three-dimensional culture, decorin reduced apoptosis. However, following the establishment of a three-dimensional matrix, the cells did not require decorin for their survival

  6. Self-assembly of polyhedral metal–organic framework particles into three-dimensional ordered superstructures

    NARCIS (Netherlands)

    Avci, Civan; Imaz, Inhar; Carné-Sánchez, Arnau; Pariente, Jose Angel; Tasios, Nikos; Pérez-Carvajal, Javier; Alonso, Maria Isabel; Blanco, Alvaro; Dijkstra, M.; López, Cefe; Maspoch, Daniel

    Self-assembly of particles into long-range, three-dimensional, ordered superstructures is crucial for the design of a variety of materials, including plasmonic sensing materials, energy or gas storage systems, catalysts and photonic crystals. Here, we have combined experimental and simulation data

  7. Engineering three-dimensional cell mechanical microenvironment with hydrogels.

    Science.gov (United States)

    Huang, Guoyou; Wang, Lin; Wang, Shuqi; Han, Yulong; Wu, Jinhui; Zhang, Qiancheng; Xu, Feng; Lu, Tian Jian

    2012-12-01

    Cell mechanical microenvironment (CMM) significantly affects cell behaviors such as spreading, migration, proliferation and differentiation. However, most studies on cell response to mechanical stimulation are based on two-dimensional (2D) planar substrates, which cannot mimic native three-dimensional (3D) CMM. Accumulating evidence has shown that there is a significant difference in cell behavior in 2D and 3D microenvironments. Among the materials used for engineering 3D CMM, hydrogels have gained increasing attention due to their tunable properties (e.g. chemical and mechanical properties). In this paper, we provide an overview of recent advances in engineering hydrogel-based 3D CMM. Effects of mechanical cues (e.g. hydrogel stiffness and externally induced stress/strain in hydrogels) on cell behaviors are described. A variety of approaches to load mechanical stimuli in 3D hydrogel-based constructs are also discussed.

  8. Engineering three-dimensional cell mechanical microenvironment with hydrogels

    International Nuclear Information System (INIS)

    Huang Guoyou; Wang Lin; Han Yulong; Zhang Qiancheng; Xu Feng; Lu Tianjian; Wang Shuqi; Wu Jinhui

    2012-01-01

    Cell mechanical microenvironment (CMM) significantly affects cell behaviors such as spreading, migration, proliferation and differentiation. However, most studies on cell response to mechanical stimulation are based on two-dimensional (2D) planar substrates, which cannot mimic native three-dimensional (3D) CMM. Accumulating evidence has shown that there is a significant difference in cell behavior in 2D and 3D microenvironments. Among the materials used for engineering 3D CMM, hydrogels have gained increasing attention due to their tunable properties (e.g. chemical and mechanical properties). In this paper, we provide an overview of recent advances in engineering hydrogel-based 3D CMM. Effects of mechanical cues (e.g. hydrogel stiffness and externally induced stress/strain in hydrogels) on cell behaviors are described. A variety of approaches to load mechanical stimuli in 3D hydrogel-based constructs are also discussed. (topical review)

  9. A Fokker-Planck-Landau collision equation solver on two-dimensional velocity grid and its application to particle-in-cell simulation

    Energy Technology Data Exchange (ETDEWEB)

    Yoon, E. S.; Chang, C. S., E-mail: cschang@pppl.gov [Princeton Plasma Physics Laboratory, Princeton University, Princeton, New Jersey 08543 (United States); Korea Advanced Institute of Science and Technology, Yuseong-gu, DaeJeon 305-701 (Korea, Republic of)

    2014-03-15

    An approximate two-dimensional solver of the nonlinear Fokker-Planck-Landau collision operator has been developed using the assumption that the particle probability distribution function is independent of gyroangle in the limit of strong magnetic field. The isotropic one-dimensional scheme developed for nonlinear Fokker-Planck-Landau equation by Buet and Cordier [J. Comput. Phys. 179, 43 (2002)] and for linear Fokker-Planck-Landau equation by Chang and Cooper [J. Comput. Phys. 6, 1 (1970)] have been modified and extended to two-dimensional nonlinear equation. In addition, a method is suggested to apply the new velocity-grid based collision solver to Lagrangian particle-in-cell simulation by adjusting the weights of marker particles and is applied to a five dimensional particle-in-cell code to calculate the neoclassical ion thermal conductivity in a tokamak plasma. Error verifications show practical aspects of the present scheme for both grid-based and particle-based kinetic codes.

  10. Relativistic Collisions of Structured Atomic Particles

    CERN Document Server

    Voitkiv, Alexander

    2008-01-01

    The book reviews the progress achieved over the last decade in the study of collisions between an ion and an atom in which both the atomic particles carry electrons and can undergo transitions between their internal states -- including continua. It presents the detailed considerations of different theoretical approaches, that can be used to describe collisions of structured atomic particles for the very broad interval of impact energies ranging from 0.5--1 MeV/u till extreme relativistic energies where the collision velocity very closely approaches the speed of light.

  11. The L1-shell ionisation of atoms by relativistic particles

    International Nuclear Information System (INIS)

    Moiseiwitsch, B.L.; Norrington, P.H.

    1979-01-01

    An expression for the L 1 -shell ionisation cross sections of atoms by high-energy particles has been derived using the relativistic plane-wave Born approximation. The incident and scattered particles are described by Dirac plane waves while Darwin hydrogenic wavefunctions are used for the atomic electrons. A comparison is made with experimental total cross sections for incident electrons in the energy range 1-2 MeV. The agreement is a considerable improvement on that obtained using the non-relativistic planewave Born approximation. (author)

  12. Two-spinor description of massive particles and relativistic spin projection operators

    Directory of Open Access Journals (Sweden)

    A.P. Isaev

    2018-04-01

    Full Text Available On the basis of the Wigner unitary representations of the covering group ISL(2,C of the Poincaré group, we obtain spin-tensor wave functions of free massive particles with arbitrary spin. The wave functions automatically satisfy the Dirac–Pauli–Fierz equations. In the framework of the two-spinor formalism we construct spin-vectors of polarizations and obtain conditions that fix the corresponding relativistic spin projection operators (Behrends–Fronsdal projection operators. With the help of these conditions we find explicit expressions for relativistic spin projection operators for integer spins (Behrends–Fronsdal projection operators and then find relativistic spin projection operators for half integer spins. These projection operators determine the numerators in the propagators of fields of relativistic particles. We deduce generalizations of the Behrends–Fronsdal projection operators for arbitrary space–time dimensions D>2.

  13. Cryo-electron microscopy and three-dimensional reconstructions of hepatitis C virus particles

    International Nuclear Information System (INIS)

    Yu Xuekui; Qiao Ming; Atanasov, Ivo; Hu Zongyi; Kato, Takanobu; Liang, T. Jake; Zhou, Z. Hong

    2007-01-01

    The structural details of hepatitis C virus (HCV) have been elusive because of the lack of a robust tissue culture system for producing an adequate amount of virions from infectious sources for in-depth three-dimensional (3D) structural analysis. Using both negative-stain and cryo-electron microscopy (cryoEM), we show that HCV virions isolated from cell culture have a rather uniform size of 500 A in diameter and that recombinantly expressed HCV-like particles (HCV-LPs) have similar morphologic, biophysical and antigenic features in spite of the varying sizes of the particles. 3D reconstructions were obtained from HCV-LPs with the same size as the HCV virions in the presence and absence of monoclonal antibodies bound to the E1 glycoprotein. The 3D reconstruction of HCV-LP reveals a multilayered architecture, with smooth outer-layer densities arranged in a 'fishbone' configuration. Reconstruction of the particles in complex with anti-E1 antibodies shows that sites of the E1 epitope are exposed and surround the 5-, 3- and 2-fold axes. The binding pattern of the anti-E1 antibody and the fitting of the structure of the dengue virus E glycoprotein into our 3D reconstructions further suggest that the HCV-LP E1 and E2 proteins form a tetramer (or dimer of heterodimers) that corresponds morphologically and functionally to the flavivirus E homodimer. This first 3D structural analysis of HCV particles offers important insights into the elusive mechanisms of HCV assembly and maturation

  14. Three-pion Hanbury Brown-Twiss correlations in relativistic heavy-ion collisions from the STAR experiment.

    Science.gov (United States)

    Adams, J; Adler, C; Ahammed, Z; Allgower, C; Amonett, J; Anderson, B D; Anderson, M; Arkhipkin, D; Averichev, G S; Balewski, J; Barannikova, O; Barnby, L S; Baudot, J; Bekele, S; Belaga, V V; Bellwied, R; Berger, J; Bichsel, H; Billmeier, A; Bland, L C; Blyth, C O; Bonner, B E; Botje, M; Boucham, A; Brandin, A; Bravar, A; Cadman, R V; Cai, X Z; Caines, H; Calderón de la Barca Sánchez, M; Cardenas, A; Carroll, J; Castillo, J; Castro, M; Cebra, D; Chaloupka, P; Chattopadhyay, S; Chen, Y; Chernenko, S P; Cherney, M; Chikanian, A; Choi, B; Christie, W; Coffin, J P; Cormier, T M; Mora Corral, M; Cramer, J G; Crawford, H J; Derevschikov, A A; Didenko, L; Dietel, T; Draper, J E; Dunin, V B; Dunlop, J C; Eckardt, V; Efimov, L G; Emelianov, V; Engelage, J; Eppley, G; Erazmus, B; Fachini, P; Faine, V; Faivre, J; Fatemi, R; Filimonov, K; Finch, E; Fisyak, Y; Flierl, D; Foley, K J; Fu, J; Gagliardi, C A; Gagunashvili, N; Gans, J; Gaudichet, L; Germain, M; Geurts, F; Ghazikhanian, V; Grachov, O; Guedon, M; Guertin, S M; Gushin, E; Gutierrez, T D; Hallman, T J; Hardtke, D; Harris, J W; Heinz, M; Henry, T W; Heppelmann, S; Herston, T; Hippolyte, B; Hirsch, A; Hjort, E; Hoffmann, G W; Horsley, M; Huang, H Z; Humanic, T J; Igo, G; Ishihara, A; Jacobs, P; Jacobs, W W; Janik, M; Johnson, I; Jones, P G; Judd, E G; Kabana, S; Kaneta, M; Kaplan, M; Keane, D; Kiryluk, J; Kisiel, A; Klay, J; Klein, S R; Klyachko, A; Kollegger, T; Konstantinov, A S; Kopytine, M; Kotchenda, L; Kovalenko, A D; Kramer, M; Kravtsov, P; Krueger, K; Kuhn, C; Kulikov, A I; Kunde, G J; Kunz, C L; Kutuev, R Kh; Kuznetsov, A A; Lamont, M A C; Landgraf, J M; Lange, S; Lansdell, C P; Lasiuk, B; Laue, F; Lauret, J; Lebedev, A; Lednický, R; Leontiev, V M; LeVine, M J; Li, Q; Lindenbaum, S J; Lisa, M A; Liu, F; Liu, L; Liu, Z; Liu, Q J; Ljubicic, T; Llope, W J; Long, H; Longacre, R S; Lopez-Noriega, M; Love, W A; Ludlam, T; Lynn, D; Ma, J; Ma, Y G; Magestro, D; Majka, R; Margetis, S; Markert, C; Martin, L; Marx, J; Matis, H S; Matulenko, Yu A; McShane, T S; Meissner, F; Melnick, Yu; Meschanin, A; Messer, M; Miller, M L; Milosevich, Z; Minaev, N G; Mitchell, J; Molnar, L; Moore, C F; Morozov, V; de Moura, M M; Munhoz, M G; Nelson, J M; Nevski, P; Nikitin, V A; Nogach, L V; Norman, B; Nurushev, S B; Odyniec, G; Ogawa, A; Okorokov, V; Oldenburg, M; Olson, D; Paic, G; Pandey, S U; Panebratsev, Y; Panitkin, S Y; Pavlinov, A I; Pawlak, T; Perevoztchikov, V; Peryt, W; Petrov, V A; Picha, R; Planinic, M; Pluta, J; Porile, N; Porter, J; Poskanzer, A M; Potrebenikova, E; Prindle, D; Pruneau, C; Putschke, J; Rai, G; Rakness, G; Ravel, O; Ray, R L; Razin, S V; Reichhold, D; Reid, J G; Renault, G; Retiere, F; Ridiger, A; Ritter, H G; Roberts, J B; Rogachevski, O V; Romero, J L; Rose, A; Roy, C; Rykov, V; Sakrejda, I; Salur, S; Sandweiss, J; Savin, I; Schambach, J; Scharenberg, R P; Schmitz, N; Schroeder, L S; Schweda, K; Seger, J; Seyboth, P; Shahaliev, E; Shestermanov, K E; Shimanskii, S S; Simon, F; Skoro, G; Smirnov, N; Snellings, R; Sorensen, P; Sowinski, J; Spinka, H M; Srivastava, B; Stephenson, E J; Stock, R; Stolpovsky, A; Strikhanov, M; Stringfellow, B; Struck, C; Suaide, A A P; Sugarbaker, E; Suire, C; Sumbera, M; Surrow, B; Symons, T J M; Szanto de Toledo, A; Szarwas, P; Tai, A; Takahashi, J; Tang, A H; Thein, D; Thomas, J H; Thompson, M; Timoshenko, S; Tokarev, M; Tonjes, M B; Trainor, T A; Trentalange, S; Tribble, R E; Trofimov, V; Tsai, O; Ullrich, T; Underwood, D G; Van Buren, G; Vander Molen, A M; Vasiliev, A N; Vigdor, S E; Voloshin, S A; Vznuzdaev, M; Wang, F; Wang, Y; Ward, H; Watson, J W; Wells, R; Westfall, G D; Whitten, C; Wieman, H; Willson, R; Wissink, S W; Witt, R; Wood, J; Xu, N; Xu, Z; Yakutin, A E; Yamamoto, E; Yang, J; Yepes, P; Yurevich, V I; Zanevski, Y V; Zborovský, I; Zhang, H; Zhang, W M; Zoulkarneev, R; Zoulkarneeva, J; Zubarev, A N

    2003-12-31

    Data from the first physics run at the Relativistic Heavy-Ion Collider at Brookhaven National Laboratory, Au+Au collisions at sqrt[s(NN)]=130 GeV, have been analyzed by the STAR Collaboration using three-pion correlations with charged pions to study whether pions are emitted independently at freeze-out. We have made a high-statistics measurement of the three-pion correlation function and calculated the normalized three-particle correlator to obtain a quantitative measurement of the degree of chaoticity of the pion source. It is found that the degree of chaoticity seems to increase with increasing particle multiplicity.

  15. IBSIMU: A three-dimensional simulation software for charged particle optics

    Energy Technology Data Exchange (ETDEWEB)

    Kalvas, T.; Tarvainen, O.; Ropponen, T.; Steczkiewicz, O.; Aerje, J. [Department of Physics, University of Jyvaeskylae, Jyvaeskylae 40500 (Finland); Clark, H. [Cyclotron Institute, Texas A and M University, College Station, Texas 77843 (United States)

    2010-02-15

    A general-purpose three-dimensional (3D) simulation code IBSIMU for charged particle optics with space charge is under development at JYFL. The code was originally developed for designing a slit-beam plasma extraction and nanosecond scale chopping for pulsed neutron generator, but has been developed further and has been used for many applications. The code features a nonlinear FDM Poisson's equation solver based on fast stabilized biconjugate gradient method with ILU0 preconditioner for solving electrostatic fields. A generally accepted nonlinear plasma model is used for plasma extraction. Magnetic fields can be imported to the simulations from other programs. The particle trajectories are solved using adaptive Runge-Kutta method. Steady-state and time-dependent problems can be modeled in cylindrical coordinates, two-dimensional (slit) geometry, or full 3D. The code is used via C++ programming language for versatility but it features an interactive easy-to-use postprocessing tool for diagnosing fields and particle trajectories. The open source distribution and public documentation make the code well suited for scientific use. IBSIMU has been used for modeling the 14 GHz ECR ion source extraction and for designing a four-electrode extraction for a 2.45 GHz microwave ion source at Jyvaeskylae. A grid extraction has also been designed for producing large uniform beam for creating conditions similar to solar wind. The code has also been used to design a H{sup -} extraction with electron dumping for the Cyclotron Institute of Texas A and M University.

  16. Localization of relativistic particles

    International Nuclear Information System (INIS)

    Omnes, R.

    1997-01-01

    In order to discuss localization experiments and also to extend the consistent history interpretation of quantum mechanics to relativistic properties, the techniques introduced in a previous paper [J. Math. Phys. 38, 697 (1997)] are applied to the localization of a photon in a given region of space. An essential requirement is to exclude arbitrarily large wavelengths. The method is valid for a particle with any mass and spin. Though there is no proper position operator for a photon, one never needs one in practice. Causality is valid up to exponentially small corrections. copyright 1997 American Institute of Physics

  17. Three-Dimensional, Transgenic Cell Models to Quantify Space Genotoxic Effects

    Science.gov (United States)

    Gonda, S. R.; Sognier, M. A.; Wu, H.; Pingerelli, P. L.; Glickman, B. W.; Dawson, David L. (Technical Monitor)

    1999-01-01

    The space environment contains radiation and chemical agents known to be mutagenic and carcinogenic to humans. Additionally, microgravity is a complicating factor that may modify or synergize induced genotoxic effects. Most in vitro models fail to use human cells (making risk extrapolation to humans more difficult), overlook the dynamic effect of tissue intercellular interactions on genotoxic damage, and lack the sensitivity required to measure low-dose effects. Currently a need exists for a model test system that simulates cellular interactions present in tissue, and can be used to quantify genotoxic damage induced by low levels of radiation and chemicals, and extrapolate assessed risk to humans. A state-of-the-art, three-dimensional, multicellular tissue equivalent cell culture model will be presented. It consists of mammalian cells genetically engineered to contain multiple copies of defined target genes for genotoxic assessment,. NASA-designed bioreactors were used to coculture mammalian cells into spheroids, The cells used were human mammary epithelial cells (H184135) and Stratagene's (Austin, Texas) Big Blue(TM) Rat 2 lambda fibroblasts. The fibroblasts were genetically engineered to contain -a high-density target gene for mutagenesis (60 copies of lacl/LacZ per cell). Tissue equivalent spheroids were routinely produced by inoculation of 2 to 7 X 10(exp 5) fibroblasts with Cytodex 3 beads (150 micrometers in diameter). at a 20:1 cell:bead ratio, into 50-ml HARV bioreactors (Synthecon, Inc.). Fibroblasts were cultured for 5 days, an equivalent number of epithelial cells added, and the fibroblast/epithelial cell coculture continued for 21 days. Three-dimensional spheroids with diameters ranging from 400 to 600 micrometers were obtained. Histological and immunohistochemical Characterization revealed i) both cell types present in the spheroids, with fibroblasts located primarily in the center, surrounded by epithelial cells; ii) synthesis of extracellular matrix

  18. Explicit symplectic algorithms based on generating functions for relativistic charged particle dynamics in time-dependent electromagnetic field

    Science.gov (United States)

    Zhang, Ruili; Wang, Yulei; He, Yang; Xiao, Jianyuan; Liu, Jian; Qin, Hong; Tang, Yifa

    2018-02-01

    Relativistic dynamics of a charged particle in time-dependent electromagnetic fields has theoretical significance and a wide range of applications. The numerical simulation of relativistic dynamics is often multi-scale and requires accurate long-term numerical simulations. Therefore, explicit symplectic algorithms are much more preferable than non-symplectic methods and implicit symplectic algorithms. In this paper, we employ the proper time and express the Hamiltonian as the sum of exactly solvable terms and product-separable terms in space-time coordinates. Then, we give the explicit symplectic algorithms based on the generating functions of orders 2 and 3 for relativistic dynamics of a charged particle. The methodology is not new, which has been applied to non-relativistic dynamics of charged particles, but the algorithm for relativistic dynamics has much significance in practical simulations, such as the secular simulation of runaway electrons in tokamaks.

  19. Perpendicular relativistic shocks in magnetized pair plasma

    Science.gov (United States)

    Plotnikov, Illya; Grassi, Anna; Grech, Mickael

    2018-04-01

    Perpendicular relativistic (γ0 = 10) shocks in magnetized pair plasmas are investigated using two dimensional Particle-in-Cell simulations. A systematic survey, from unmagnetized to strongly magnetized shocks, is presented accurately capturing the transition from Weibel-mediated to magnetic-reflection-shaped shocks. This transition is found to occur for upstream flow magnetizations 10-3 10-2, it leaves place to a purely electromagnetic precursor following from the strong emission of electromagnetic waves at the shock front. Particle acceleration is found to be efficient in weakly magnetized perpendicular shocks in agreement with previous works, and is fully suppressed for σ > 10-2. Diffusive Shock Acceleration is observed only in weakly magnetized shocks, while a dominant contribution of Shock Drift Acceleration is evidenced at intermediate magnetizations. The spatial diffusion coefficients are extracted from the simulations allowing for a deeper insight into the self-consistent particle kinematics and scale with the square of the particle energy in weakly magnetized shocks. These results have implications for particle acceleration in the internal shocks of AGN jets and in the termination shocks of Pulsar Wind Nebulae.

  20. Deposition of nano-size particles on reticulated vitreous carbon using colloidal precursors : three-dimensional anodes for borohydride fuel cells

    Energy Technology Data Exchange (ETDEWEB)

    Choi, J.; Gyenge, E.L. [British Columbia Univ., Vancouver, BC (Canada). Dept. of Chemical and Biological Engineering

    2006-07-01

    In addition to their inherently larger specific surface area, mesoscopic materials also possess a higher density of surface constrained sites, which could serve as active sites in catalysis as well as facilitate the surface diffusion of small molecules and ions relevant to various catalytic steps. This study investigated the organosol method for the deposition of platinum (Pt), iridium (Ir), gold (Au) and nickel (Ni) nano-particles on reticulated vitreous carbon to evaluate the electrocatalytic activity for BH{sub 4} oxidation by both fundamental electrochemical studies and fuel cell experiments. The application of the organosol nanometal preparation technique was based on the quaternary ammonium compound N(C{sub 8}H{sub 17}){sub 4}B(C{sub 2}H{sub 5}){sub 3}H acting as both reductant and colloid stabilizer. A current assisted variant was also studied where the reticulated vitreous carbon substrate served as the cathode operating at superficial current densities between 1.0 and 2.5 mA per cm{sup 2}. The organosol method produced a low catalyst load on reticulated vitreous carbons between 0.01 and 0.12 mg per cm{sup 2}. The electrodes were evaluated for catalytic activity toward the electro-oxidation of BH{sub 4} by cyclic voltammetry, chronopotentiometry and fuel cell experiments. Borohydride fuel cells with liquid electrolyte (2 M NaOH) were assembled using a 3-dimensional anode, a cation exchange membrane and a commercial oxygen cathode. Results showed that the anode catalyst mass activity was higher for the 3-D design compared to the case when a gas diffusion electrode served as the anode. It was concluded that the extended reaction zone of the three-dimensional anode with liquid electrolyte improved the catalyst utilization efficiency by allowing the reduction of the catalyst load. 6 refs., 1 fig.

  1. On the relativistic particle dynamics in external gravitational fields

    International Nuclear Information System (INIS)

    Kuz'menkov, L.S.; Naumov, N.D.

    1977-01-01

    On the base of the Riemann metrics of an event space, leading to the Newton mechanics at nonrelativistic velocities and not obligatory weak gravitational fields relativistic particle dynamics in external gravitation fields has been considered. Found are trajectories, motion laws and light ray equations for the homogeneous and Newton fields

  2. The CNCSN: one, two- and three-dimensional coupled neutral and charged particle discrete ordinates code package

    International Nuclear Information System (INIS)

    Voloschenko, A.M.; Gukov, S.V.; Kryuchkov, V.P.; Dubinin, A.A.; Sumaneev, O.V.

    2005-01-01

    The CNCSN package is composed of the following codes: -) KATRIN-2.0: a three-dimensional neutral and charged particle transport code; -) KASKAD-S-2.5: a two-dimensional neutral and charged particle transport code; -) ROZ-6.6: a one-dimensional neutral and charged particle transport code; -) ARVES-2.5: a preprocessor for the working macroscopic cross-section format FMAC-M for transport calculations; -) MIXERM: a utility code for preparing mixtures on the base of multigroup cross-section libraries in ANISN format; -) CEPXS-BFP: a version of the Sandia National Lab. multigroup coupled electron-photon cross-section generating code CEPXS, adapted for solving the charged particles transport in the Boltzmann-Fokker-Planck formulation with the use of discrete ordinate method; -) SADCO-2.4: Institute for High-Energy Physics modular system for generating coupled nuclear data libraries to provide high-energy particles transport calculations by multigroup method; -) KATRIF: the post-processor for the KATRIN code; -) KASF: the post-processor for the KASKAD-S code; and ROZ6F: the post-processor for the ROZ-6 code. The coding language is Fortran-90

  3. Reversible gelling culture media for in-vitro cell culture in three-dimensional matrices

    Science.gov (United States)

    An, Yuehuei H.; Mironov, Vladimir A.; Gutowska, Anna

    2000-01-01

    A gelling cell culture medium useful for forming a three dimensional matrix for cell culture in vitro is prepared by copolymerizing an acrylamide derivative with a hydrophilic comonomer to form a reversible (preferably thermally reversible) gelling linear random copolymer in the form of a plurality of linear chains having a plurality of molecular weights greater than or equal to a minimum gelling molecular weight cutoff, mixing the copolymer with an aqueous solvent to form a reversible gelling solution and adding a cell culture medium to the gelling solution to form the gelling cell culture medium. Cells such as chondrocytes or hepatocytes are added to the culture medium to form a seeded culture medium, and temperature of the medium is raised to gel the seeded culture medium and form a three dimensional matrix containing the cells. After propagating the cells in the matrix, the cells may be recovered by lowering the temperature to dissolve the matrix and centrifuging.

  4. The ionisation loss of relativistic charged particles in thin gas samples and its use for particle identification. I

    International Nuclear Information System (INIS)

    Cobb, J.H.; Allison, W.W.M.; Bunch, J.N.

    1976-01-01

    A brief review shows a significant discrepancy between available data and theoretical predictions on the ionisation loss of charged particles in thin gas-filled proportional counters. The discrepancy related both to the increase of the most probable loss at relativistic velocities (relativistic rise) and to the spectrum of such losses at a given velocity (the Landau distribution). The origin of this relativistic rise is discussed in simple terms and related to the phenomena of transition radiation and Cherenkov radiation. It is shown that the failure of the prediction is due to the small number of ionising collisions in a gas. This problem is overcome by using a Monte Carlo method rather than a continuous integral over the spectrum of single collision processes. A specific mode of the atomic form factors is used with a modified Born approximation to yield the differential cross sections needed for the calculation. The new predictions give improved agreement with experiment and are used to investigate the problem of identifying particles of known momenta in the relativistic region. It is shown that by measuring the ionisation loss of each particle several hundred times over 5m or more, kaon, pion and proton separation with good confidence level may be achieved. Many gases are considered and a comparison is made. The results are also compared with the velocity resolution achievable by measuring primary ionisation. (Auth.)

  5. Quantification of plant cell coupling with three-dimensional photoactivation microscopy.

    Science.gov (United States)

    Liesche, J; Schulz, A

    2012-07-01

    Plant cells are directly connected by plasmodesmata that form channels through the cell wall and enable the intercellular movement of cytosolic solutes, membrane lipids and signalling molecules. Transport through plasmodesmata is regulated not only by a fixed size-exclusion limit, but also by physiological and pathological adaptation. To understand plant cell communication, carbon allocation and pathogen attack, the capacities for a specific molecule to pass a specific cell-wall interface is an essential parameter. So far, the degree of cell coupling was derived from frequency and diameter of plasmodesmata in relevant tissues as assessed by electron microscopy of fixed material. However, plasmodesmata functionality and capacity can only be determined in live material, not from electron microscopy, which is static and prone to fixation artefacts. Plasmodesmata functionality was a few times assessed using fluorescent tracers with diffusion properties similar to cytosolic solutes. Here, we used three-dimensional photoactivation microscopy to quantify plasmodesmata-mediated cell-wall permeability between living Cucurbita maxima leaf mesophyll cells with caged fluorescein as tracer. For the first time, all necessary functional and anatomical data were gathered for each individual cell from three-dimensional time series. This approach utilized a confocal microscope equipped with resonant scanner, which provides the high acquisition speed necessary to record optical sections of whole cells and offers time resolution high enough to follow the kinetics of photoactivation. The results were compared to two-dimensional measurements, which are shown to give a good estimate of cell coupling adequate for homogenous tissues. The two-dimensional approach is limited whenever tissues interfaces are studied that couple different cell types with diverse cell geometries. © 2011 The Authors Journal of Microscopy © 2011 Royal Microscopical Society.

  6. Electromagnetic field of a circular beam of relativistic particles

    International Nuclear Information System (INIS)

    Vybiral, B.

    1978-01-01

    The generalized Coulomb law and the generalized Biot-Savart-Laplace law are derived for an element of a beam of charged relativistic particles moving generally irregularly. These laws are utilized for the description of an electromagnetic field of a circular beam of relativistic regularly moving particles. It is shown that in the points on the axis of the beam the intensity of the electric field is given by an expression precisely corresponding to the classical Coulomb law for charges at rest and the induction of the magnetic field corresponds to the classical Biot-Savart-Laplace law for conductive currents. From the numerical solution it follows that in the points outside the axis the induction of the magnetic field rises with the velocity of the particles. For a velocity nearing that of light in vacuum it assumes a definite value (with the exception of the points lying on the beam). (author)

  7. Three dimensional particle simulation of drift wave fluctuations in a sheared magnetic field

    International Nuclear Information System (INIS)

    Sydora, R.D.; Leboeuf, J.N.; Thayer, D.R.; Diamond, P.H.; Tajima, T.

    1985-08-01

    Three dimensional particle simulations of collisionless drift waves in sheared magnetic fields were performed in order to determine the nonlinear behavior of inverse electron resonance dynamics in the presence of thermal fluctuations. It is found that stochastic electron diffusion in the electron resonance overlap region can destabilize the drift wave eigenmodes. Numerical evaluations based on a nonlinear electron resonance broadening theory give predictions in accord with the frequency and growth rates found in the simulation of short wavelength modes (k/sub y/rho/sub s/ greater than or equal to1)

  8. The three-dimensional, discrete ordinates neutral particle transport code TORT: An overview

    International Nuclear Information System (INIS)

    Azmy, Y.Y.

    1996-01-01

    The centerpiece of the Discrete Ordinates Oak Ridge System (DOORS), the three-dimensional neutral particle transport code TORT is reviewed. Its most prominent features pertaining to large applications, such as adjustable problem parameters, memory management, and coarse mesh methods, are described. Advanced, state-of-the-art capabilities including acceleration and multiprocessing are summarized here. Future enhancement of existing graphics and visualization tools is briefly presented

  9. Dynamics of the relativistic acceleration of charged particles in space plasma while surfing the package electromagnetic waves

    International Nuclear Information System (INIS)

    Erokhin, N.S.; Zol'nikova, N.N.; Kuznetsov, E.A.; Mikhajlovskaya, L.A.

    2010-01-01

    Based on numerical calculations considered the relativistic acceleration of charged particles in space plasma when surfing on the spatially localized package of electromagnetic waves. The problem is reduced to the study of unsteady, nonlinear equation for the wave phase at the carrier frequency at the location of the accelerated charge, which is solved numerically. We study the temporal dynamics of the relativistic factor, the component of momentum and velocity of the particle, its trajectory is given gyro-rotation in an external magnetic field after the departure of the effective potential well. Dependence of the dynamics of a particle interacting with the wave of the sign of the velocity of the charge along the wave front. We formulate the optimal conditions of the relativistic particle acceleration wave packet, indicate the possibility of again (after a number gyro-turnover) charge trapping wave with an additional relativistic acceleration.

  10. Relativistic ion acceleration by ultraintense laser interactions

    International Nuclear Information System (INIS)

    Nakajima, K.; Koga, J.K.; Nakagawa, K.

    2001-01-01

    There has been a great interest in relativistic particle generation by ultraintense laser interactions with matter. We propose the use of relativistically self-focused laser pulses for the acceleration of ions. Two dimensional PIC simulations are performed, which show the formation of a large positive electrostatic field near the front of a relativistically self-focused laser pulse. Several factors contribute to the acceleration including self-focusing distance, pulse depletion, and plasma density. Ultraintense laser-plasma interactions are capable of generating enormous electrostatic fields of ∼3 TV/m for acceleration of protons with relativistic energies exceeding 1 GeV

  11. Single florescent nanodiamond in a three dimensional ABEL trap

    Science.gov (United States)

    Kayci, Metin; Radenovic, Aleksandra

    2015-01-01

    Three dimensional single particle trapping and manipulation is an outstanding challenge in various fields ranging from basic physics to life sciences. By monitoring the response of a trapped particle to a designed environment one can extract its characteristics. In addition, quantum dynamics of a spatially scanned well-known particle can provide environmental information. Precise tracking and positioning of such a particle in aqueous environment is crucial task for achieving nano-scale resolution. Here we experimentally demonstrate three dimensional ABEL trap operating at high frequency by employing a hybrid approach in particle tracking. The particle location in the transverse plane is detected via a scanning laser beam while the axial position is determined by defocused imaging. The scanning of the trapped particle is accomplished through a nano positioning stage integrated to the trap platform. PMID:26559890

  12. Particle production and Boltzmann integral form of relativistic quantum transport theory

    International Nuclear Information System (INIS)

    Rafelski, J.; Davis, E.D.; Bialynicki-Birula, I.

    1993-01-01

    The 3+3+1 dimensional relativistic quantum transport equation for the fermion matter field, combines the particle pair production with flow phenomena, which occur at very different time scale. A direct numerical treatment of dynamical situations is therefore practically impossible. The authors attempt a seperation of these two sectors by the method of prediagonalization of the integral equations. They exploit the structure of the resolvent of the transport equations: it contains two poles corresponding to the flow sector and two to the pair production sector. Their hope for practical applications is to treat matter flow as a classical phenomenon and to be able to obtain an integral term describing the pair production accurately

  13. Relativistic equation of the orbit of a particle in a arbitrary central force field

    International Nuclear Information System (INIS)

    Aaron, Francisc D.

    2005-01-01

    The equation of the orbit of a relativistic particle moving in an arbitrary central force field is derived. Straightforward generalizations of well-known first and second order differential equations are given. It is pointed out that the relativistic equation of the orbit has the same form as in the non-relativistic case, the only changes consisting in the appearance of additional terms proportional to 1/c 2 in both potential and total energies. (author)

  14. RELATIVISTIC CYCLOTRON INSTABILITY IN ANISOTROPIC PLASMAS

    Energy Technology Data Exchange (ETDEWEB)

    López, Rodrigo A.; Moya, Pablo S.; Muñoz, Víctor; Valdivia, J. Alejandro [Departamento de Física, Facultad de Ciencias, Universidad de Chile, Casilla 653, Santiago (Chile); Navarro, Roberto E.; Araneda, Jaime A. [Departamento de Física, Facultad de Ciencias Físicas y Matemáticas, Universidad de Concepción, Casilla 160-C, Concepción (Chile); Viñas, Adolfo F., E-mail: rlopez186@gmail.com [NASA Goddard Space Flight Center, Heliophysics Science Division, Geospace Physics Laboratory, Mail Code 673, Greenbelt, MD 20771 (United States)

    2016-11-20

    A sufficiently large temperature anisotropy can sometimes drive various types of electromagnetic plasma micro-instabilities, which can play an important role in the dynamics of relativistic pair plasmas in space, astrophysics, and laboratory environments. Here, we provide a detailed description of the cyclotron instability of parallel propagating electromagnetic waves in relativistic pair plasmas on the basis of a relativistic anisotropic distribution function. Using plasma kinetic theory and particle-in-cell simulations, we study the influence of the relativistic temperature and the temperature anisotropy on the collective and noncollective modes of these plasmas. Growth rates and dispersion curves from the linear theory show a good agreement with simulations results.

  15. Sparse grid techniques for particle-in-cell schemes

    Science.gov (United States)

    Ricketson, L. F.; Cerfon, A. J.

    2017-02-01

    We propose the use of sparse grids to accelerate particle-in-cell (PIC) schemes. By using the so-called ‘combination technique’ from the sparse grids literature, we are able to dramatically increase the size of the spatial cells in multi-dimensional PIC schemes while paying only a slight penalty in grid-based error. The resulting increase in cell size allows us to reduce the statistical noise in the simulation without increasing total particle number. We present initial proof-of-principle results from test cases in two and three dimensions that demonstrate the new scheme’s efficiency, both in terms of computation time and memory usage.

  16. Bmad: A relativistic charged particle simulation library

    International Nuclear Information System (INIS)

    Sagan, D.

    2006-01-01

    Bmad is a subroutine library for simulating relativistic charged particle beams in high-energy accelerators and storage rings. Bmad can be used to study both single and multi-particle beam dynamics using routines to track both particles and macroparticles. Bmad has various tracking algorithms including Runge-Kutta and symplectic (Lie algebraic) integration. Various effects such as wakefields, and radiation excitation and damping can be simulated. Bmad has been developed in a modular, object-oriented fashion to maximize flexibility. Interface routines allow Bmad to be called from C/C++ as well as Fortran programs. Bmad is well documented. Every routine is individually annotated, and there is an extensive manual

  17. Three-dimensional random resistor-network model for solid oxide fuel cell composite electrodes

    International Nuclear Information System (INIS)

    Abbaspour, Ali; Luo Jingli; Nandakumar, K.

    2010-01-01

    A three-dimensional reconstruction of solid oxide fuel cell (SOFC) composite electrodes was developed to evaluate the performance and further investigate the effect of microstructure on the performance of SOFC electrodes. Porosity of the electrode is controlled by adding pore former particles (spheres) to the electrode and ignoring them in analysis step. To enhance connectivity between particles and increase the length of triple-phase boundary (TPB), sintering process is mimicked by enlarging particles to certain degree after settling them inside the packing. Geometrical characteristics such as length of TBP and active contact area as well as porosity can easily be calculated using the current model. Electrochemical process is simulated using resistor-network model and complete Butler-Volmer equation is used to deal with charge transfer process on TBP. The model shows that TPBs are not uniformly distributed across the electrode and location of TPBs as well as amount of electrochemical reaction is not uniform. Effects of electrode thickness, particle size ratio, electron and ion conductor conductivities and rate of electrochemical reaction on overall electrochemical performance of electrode are investigated.

  18. High field terahertz emission from relativistic laser-driven plasma wakefields

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Zi-Yu, E-mail: Ziyu.Chen@uni-duesseldorf.de [Institut für Theoretische Physik I, Heinrich-Heine-Universität Düsseldorf, Düsseldorf 40225 (Germany); LSD, Institute of Fluid Physics, China Academy of Engineering Physics, Mianyang 621999 (China); Pukhov, Alexander [Institut für Theoretische Physik I, Heinrich-Heine-Universität Düsseldorf, Düsseldorf 40225 (Germany)

    2015-10-15

    We propose a method to generate high field terahertz (THz) radiation with peak strength of GV/cm level in the THz frequency gap range of 1–10 THz using a relativistic laser interaction with a gaseous plasma target. Due to the effect of local pump depletion, an initially Gaussian laser pulse undergoes leading edge erosion and eventually evolves to a state with leading edge being step function. Interacting with such a pulse, electrons gain transverse residual momentum and excite net transverse currents modulated by the relativistic plasma frequency. These currents give rise to the low frequency THz emission. We demonstrate this process with one and two dimensional particle-in-cell simulations.

  19. Relativistic bound-state problem of a one-dimensional system

    International Nuclear Information System (INIS)

    Sato, T.; Niwa, T.; Ohtsubo, H.; Tamura, K.

    1991-01-01

    A Poincare-covariant description of the two-body bound-state problem in one-dimensional space is studied by using the relativistic Schrodinger equation. We derive the many-body Hamiltonian, electromagnetic current and generators of the Poincare group in the framework of one-boson exchange. Our theory satisfies Poincare algebra within the one-boson-exchange approximation. We numerically study the relativistic effects on the bound-state wavefunction and the elastic electromagnetic form factor. The Lorentz boost of the bound-state wavefunction and the two-body exchange current are shown to play an important role in guaranteeing the Lorentz invariance of the form factor. (author)

  20. Horizons in 2+1-dimensional collapse of particles

    Indian Academy of Sciences (India)

    A simple, geometrical construction is given for three-dimensional spacetimes with negative cosmological constant that contain two particles colliding head-on. Depending on parameters like particle masses and distance, the combined geometry will be that of a particle, or of a black hole. In the black hole case the horizon is ...

  1. Path integral for a relativistic-particle theory

    International Nuclear Information System (INIS)

    Fradkin, E.S.; Gitman, D.M.; Shvartsman, S.M.

    1991-01-01

    An action of a relativistic spinning particle written in reparametrization and local super-invariant form is consistently determined by using the path integral representation for the Green's function of the spinor field. It is shown that, to obtain the causal propagator, the integration over the null mode of the onebein variable must be performed in the (0, + ∞ limits

  2. Three-dimensional observation of TiO2 nanostructures by electron tomography

    KAUST Repository

    Suh, Young Joon

    2013-03-01

    Three-dimensional nanostructures of TiO2 related materials including nanotubes, electron acceptor materials in hybrid polymer solar cells, and working electrodes of dye sensitized solar cells (DSSCs) were visualized by electron tomography as well as TEM micrographs. The regions on the wall of TiO2 nanotubes where the streptavidins were attached were elucidated by electron tomogram analysis. The coverage of TiO2 nanotubes by streptavidin was also investigated. The TiO2 nanostructures in hybrid polymer solar cells made by sol-gel and atomic layer deposition (ALD) methods and the morphologies of pores between TiO2 particles in DSSCs were also observed by reconstructed three-dimensional images made by electron tomography. © 2012 Elsevier Ltd.

  3. Electron-deuteron scattering in a relativistic theory of hadrons

    International Nuclear Information System (INIS)

    Phillips, D.

    1998-11-01

    The author reviews a three-dimensional formalism that provides a systematic way to include relativistic effects including relativistic kinematics, the effects of negative-energy states, and the boosts of the two-body system in calculations of two-body bound-states. He then explains how to construct a conserved current within this relativistic three-dimensional approach. This general theoretical framework is specifically applied to electron-deuteron scattering both in impulse approximation and when the ρπγ meson-exchange current is included. The experimentally-measured quantities A, B, and T 20 are calculated over the kinematic range that is probed in Jefferson Lab experiments. The role of both negative-energy states and meson retardation appears to be small in the region of interest

  4. Relativistic electron Wigner crystal formation in a cavity for electron acceleration

    CERN Document Server

    Thomas, Johannes; Pukhov, Alexander

    2014-01-01

    It is known that a gas of electrons in a uniform neutralizing background can crystallize and form a lattice if the electron density is less than a critical value. This crystallization may have two- or three-dimensional structure. Since the wake field potential in the highly-nonlinear-broken-wave regime (bubble regime) has the form of a cavity where the background electrons are evacuated from and only the positively charged ions remain, it is suited for crystallization of trapped and accelerated electron bunch. However, in this case, the crystal is moving relativistically and shows new three-dimensional structures that we call relativistic Wigner crystals. We analyze these structures using a relativistic Hamiltonian approach. We also check for stability and phase transitions of the relativistic Wigner crystals.

  5. The de Sitter relativistic top theory

    International Nuclear Information System (INIS)

    Armenta, J.; Nieto, J.A.

    2005-01-01

    We discuss the relativistic top theory from the point of view of the de Sitter (or anti-de Sitter) group. Our treatment rests on the Hanson-Regge spherical relativistic top Lagrangian formulation. We propose an alternative method for studying spinning objects via Kaluza-Klein theory. In particular, we derive the relativistic top equations of motion starting with the geodesic equation for a point particle in 4+N dimensions. We compare our approach with Fukuyama's formulation of spinning objects, which is also based on Kaluza-Klein theory. We also report a generalization of our approach to a 4+N+D dimensional theory

  6. Relativistic Bosons in Time-Harmonic Electric Fields

    Science.gov (United States)

    Buhucianu, Ovidiu; Dariescu, Marina-Aura; Dariescu, Ciprian

    2012-02-01

    In the present paper, we consider a bi-dimensional thin sample, placed in a strong harmonically oscillating electric field and a static magnetic induction, both directed along the normal to the sample's plane. The Klein-Gordon equation describing the relativistic bosons leads to a Mathieu's type equation for the temporal part of the wave functions. It follows that, for the electric field pulsation inside a computable range, depending on the external fields intensities, the amplitude functions are turning from oscillatory to exponentially growing modes. For ultra-relativistic particles, one can recover the periodic stationary amplitude behavior.

  7. Nonthermal Particle Acceleration in 3D Relativistic Magnetic Reconnection in Pair Plasma

    Energy Technology Data Exchange (ETDEWEB)

    Werner, Gregory R.; Uzdensky, Dmitri A., E-mail: Greg.Werner@colorado.edu [Center for Integrated Plasma Studies, Physics Department, University of Colorado, 390 UCB, Boulder, CO 80309 (United States)

    2017-07-10

    As a fundamental process converting magnetic to plasma energy in high-energy astrophysical plasmas, relativistic magnetic reconnection is a leading explanation for the acceleration of particles to the ultrarelativistic energies that are necessary to power nonthermal emission (especially X-rays and gamma-rays) in pulsar magnetospheres and pulsar wind nebulae, coronae and jets of accreting black holes, and gamma-ray bursts. An important objective of plasma astrophysics is therefore the characterization of nonthermal particle acceleration (NTPA) effected by reconnection. Reconnection-powered NTPA has been demonstrated over a wide range of physical conditions using large 2D kinetic simulations. However, its robustness in realistic 3D reconnection—in particular, whether the 3D relativistic drift-kink instability (RDKI) disrupts NTPA—has not been systematically investigated, although pioneering 3D simulations have observed NTPA in isolated cases. Here, we present the first comprehensive study of NTPA in 3D relativistic reconnection in collisionless electron–positron plasmas, characterizing NTPA as the strength of 3D effects is varied systematically via the length in the third dimension and the strength of the guide magnetic field. We find that, while the RDKI prominently perturbs 3D reconnecting current sheets, it does not suppress particle acceleration, even for zero guide field; fully 3D reconnection robustly and efficiently produces nonthermal power-law particle spectra closely resembling those obtained in 2D. This finding provides strong support for reconnection as the key mechanism powering high-energy flares in various astrophysical systems. We also show that strong guide fields significantly inhibit NTPA, slowing reconnection and limiting the energy available for plasma energization, yielding steeper and shorter power-law spectra.

  8. Three-dimensional nanometry of vesicle transport in living cells using dual-focus imaging optics

    International Nuclear Information System (INIS)

    Watanabe, Tomonobu M.; Sato, Takashi; Gonda, Kohsuke; Higuchi, Hideo

    2007-01-01

    Dual-focus imaging optics for three-dimensional tracking of individual quantum dots has been developed to study the molecular mechanisms of motor proteins in cells. The new system has a high spatial and temporal precision, 2 nm in the x-y sample plane and 5 nm along the z-axis at a frame time of 2 ms. Three-dimensional positions of the vesicles labeled with quantum dots were detected in living cells. Vesicles were transported on the microtubules using 8-nm steps towards the nucleus. The steps had fluctuation of ∼20 nm which were perpendicular to the axis of the microtubule but with the constant distance from the microtubule. The most of perpendicular movement was not synchronized with the 8-nm steps, indicating that dynein moved on microtubules without changing the protofilaments. When the vesicles changed their direction of movement toward the cell membrane, they moved perpendicular with the constant distance from the microtubule. The present method is powerful tool to investigate three dimensional movement of molecules in cells with nanometer and millisecond accuracy

  9. Path integral for a relativistic-particle theory

    Energy Technology Data Exchange (ETDEWEB)

    Fradkin, E.S. (AN SSSR, Moscow (SU)); Gitman, D.M. (Moskovskij Inst. Radiotekhniki, Ehlektroniki i Automatiki, Moscow (SU)); Shvartsman, S.M. (Tomskij Pedagogicheskij Inst., Tomsk (SU))

    1991-06-01

    An action of a relativistic spinning particle written in reparametrization and local super-invariant form is consistently determined by using the path integral representation for the Green's function of the spinor field. It is shown that, to obtain the causal propagator, the integration over the null mode of the onebein variable must be performed in the (0, + {infinity}) limits.

  10. Particle identification with the OPAL jet chamber in the region of the relativistic rise

    Energy Technology Data Exchange (ETDEWEB)

    Breuker, H; Fischer, H M; Hauschild, M; Hartmann, H; Wuensch, B; Boerner, H; Burckhart, H J; Dittmar, M; Hammarstroem, R; Heuer, R D

    1987-10-15

    An important goal of the OPAL jet chamber is particle identification at high momenta by exploiting the relativistic rise of the energy loss. Extensive tests have been performed with the full scale prototype of the OPAL jet chamber to measure the energy loss in an argon-methane-isobutane mixture as function of momentum and particle species. The measurements were done under various operating conditions in order to optimise the operationg point, to investigate sources of systematic errors, to monitor the stability of the energy loss measurement and to develop calibration procedures. The particle separation capability in the region of relativistic rise has been studied at gas pressures of 3 and 4 bar. The adopted operation point represents a reasonable compromise between the requirements for particle identification and tracking accuracy.

  11. Three-dimensional manipulation of single cells using surface acoustic waves.

    Science.gov (United States)

    Guo, Feng; Mao, Zhangming; Chen, Yuchao; Xie, Zhiwei; Lata, James P; Li, Peng; Ren, Liqiang; Liu, Jiayang; Yang, Jian; Dao, Ming; Suresh, Subra; Huang, Tony Jun

    2016-02-09

    The ability of surface acoustic waves to trap and manipulate micrometer-scale particles and biological cells has led to many applications involving "acoustic tweezers" in biology, chemistry, engineering, and medicine. Here, we present 3D acoustic tweezers, which use surface acoustic waves to create 3D trapping nodes for the capture and manipulation of microparticles and cells along three mutually orthogonal axes. In this method, we use standing-wave phase shifts to move particles or cells in-plane, whereas the amplitude of acoustic vibrations is used to control particle motion along an orthogonal plane. We demonstrate, through controlled experiments guided by simulations, how acoustic vibrations result in micromanipulations in a microfluidic chamber by invoking physical principles that underlie the formation and regulation of complex, volumetric trapping nodes of particles and biological cells. We further show how 3D acoustic tweezers can be used to pick up, translate, and print single cells and cell assemblies to create 2D and 3D structures in a precise, noninvasive, label-free, and contact-free manner.

  12. On the stimulated Raman sidescattering in inhomogeneous plasmas: revisit of linear theory and three-dimensional particle-in-cell simulations

    Science.gov (United States)

    Xiao, C. Z.; Zhuo, H. B.; Yin, Y.; Liu, Z. J.; Zheng, C. Y.; Zhao, Y.; He, X. T.

    2018-02-01

    Stimulated Raman sidescattering (SRSS) in inhomogeneous plasma is comprehensively revisited on both theoretical and numerical aspects due to the increasing concern of its detriments to inertial confinement fusion. Firstly, two linear mechanisms of finite beam width and collisional effects that could suppress SRSS are investigated theoretically. Thresholds for the eigenmode and wave packet in a finite-width beam are derived as a supplement to the theory proposed by Mostrom and Kaufman (1979 Phys. Rev. Lett. 42 644). Collisional absorption of SRSS is efficient at high-density plasma and high-Z material, otherwise, it allows emission of sidescattering. Secondly, we have performed the first three-dimensional particle-in-cell simulations in the context of SRSS to investigate its linear and nonlinear effects. Simulation results are qualitatively agreed with the linear theory. SRSS with the maximum growth gain is excited at various densities, grows to an amplitude that is comparable with the pump laser, and evolutes to lower densities with a large angle of emergence. Competitions between SRSS and other parametric instabilities such as stimulated Raman backscattering, two-plasmon decay, and stimulated Brillouin scattering are discussed. These interaction processes are determined by gains, occurrence sites, scattering geometries of each instability, and will affect subsequent evolutions. Nonlinear effects of self-focusing and azimuthal magnetic field generation are observed to be accompanied with SRSS. In addition, it is found that SRSS is insensitive to ion motion, collision (low-Z material), and electron temperature.

  13. Relativistic solitons and pulsars

    Energy Technology Data Exchange (ETDEWEB)

    Karpman, V I [Inst. of Terrestrial Magnetism, Ionosphere, and Radio-Wave Propagation, Moscow; Norman, C A; ter Haar, D; Tsytovich, V N

    1975-05-01

    A production mechanism for stable electron bunches or sheets of localized electric fields is investigated which may account for pulsar radio emission. Possible soliton phenomena in a one-dimensional relativistic plasma are analyzed, and it is suggested that the motion of a relativistic soliton, or ''relaton'', along a curved magnetic-field line may produce radio emission with the correct polarization properties. A general MHD solution is obtained for relatons, the radiation produced by a relativistic particle colliding with a soliton is evaluated, and the emission by a soliton moving along a curved field line is estimated. It is noted that due to a number of severe physical restrictions, curvature radiation is not a very likely solution to the problem of pulsar radio emission. (IAA)

  14. Supersymmetric quantum mechanics in three-dimensional space, 1

    International Nuclear Information System (INIS)

    Ui, Haruo

    1984-01-01

    As a direct generalization of the model of supersymmetric quantum mechanics by Witten, which describes the motion of a spin one-half particle in the one-dimensional space, we construct a model of the supersymmetric quantum mechanics in the three-dimensional space, which describes the motion of a spin one-half particle in central and spin-orbit potentials in the context of the nonrelativistic quantum mechanics. With the simplest choice of the (super) potential, this model is shown to reduce to the model of the harmonic oscillator plus constant spin-orbit potential of unit strength of both positive and negative signs, which was studied in detail in our recent paper in connection with ''accidental degeneracy'' as well as the ''graded groups''. This simplest model is discussed in some detail as an example of the three-dimensional supersymmetric quantum mechanical system, where the supersymmetry is an exact symmetry of the system. More general choice of a polynomial superpotential is also discussed. It is shown that the supersymmetry cannot be spontaneously broken for any polynomial superpotential in our three-dimensional model; this result is contrasted to the corresponding one in the one-dimensional model. (author)

  15. Three-dimensional organization of micronuclei induced by colchicine in PtK sub 1 cells

    Energy Technology Data Exchange (ETDEWEB)

    Geraud, G.; Laquerriere, F.; Masson, C.; Arnoult, J.; Labidi, B.; Hernandez-Verdun, D. (Univ. Pierre et Marie Curie, Paris (France))

    1989-03-01

    In PtK{sub 1} cells micronucleated by colchicine, the authors previously demonstrated that some micronuclei contain a single chromosome. Here, they investigated interphase chromosome organization in micronucleated PtK{sub 1} cells using conventional electron microscopy and three-dimensional computer reconstruction. The distribution of micronuclei was not always polarized, but in some cells they formed a ring. When this occurred, centrioles and Golgi apparatus were located inside the ring. On freeze-fracture replicas, they observed that nuclear pore distinction among the micronuclei was heterogeneous, and on thin sections some micronuclei displayed an incomplete nuclear envelope, with gaps in the double membrane and areas without lamina or condensed chromatin. By autoradiography, they showed that the fibrillar dots were not sites of active transcription. They applied three dimensional reconstruction to one micronucleated cell containing 22 micronuclei whose size indicated that each micronucleus probably contained one chromosome. In this cell they demonstrated that only the smallest micronuclei had an incomplete nuclear envelope. The presence in micronuclei of either nucleoli or fibrillar dots was found to be mutually exclusive. Taken together, these findings indicate that in the diploid nuclei of PtK{sub 1} cells, the three-dimensional organization of the nucleolar domain seems to be directly controlled by the X-chromosome.

  16. Implementation of a 3D plasma particle-in-cell code on a MIMD parallel computer

    International Nuclear Information System (INIS)

    Liewer, P.C.; Lyster, P.; Wang, J.

    1993-01-01

    A three-dimensional plasma particle-in-cell (PIC) code has been implemented on the Intel Delta MIMD parallel supercomputer using the General Concurrent PIC algorithm. The GCPIC algorithm uses a domain decomposition to divide the computation among the processors: A processor is assigned a subdomain and all the particles in it. Particles must be exchanged between processors as they move. Results are presented comparing the efficiency for 1-, 2- and 3-dimensional partitions of the three dimensional domain. This algorithm has been found to be very efficient even when a large fraction (e.g. 30%) of the particles must be exchanged at every time step. On the 512-node Intel Delta, up to 125 million particles have been pushed with an electrostatic push time of under 500 nsec/particle/time step

  17. A gauge model describing N relativistic particles bound by linear forces

    International Nuclear Information System (INIS)

    Filippov, A.T.

    1988-01-01

    A relativistic model of N particles bound by linear forces is obtained by applying the gauging procedure to the linear canonical symmteries of a simple (rudimentary) nonrelativistic N-particle Lagrangian extended to relativistic phase space. The new (gauged) Lagrangian is formally Poincare invariant, the Hamiltonian is a linear combination of first-class constraints which are closed with respect to Pisson brackets and generate the localized canonical symmteries. The gauge potentials appear as the Lagrange multipliers of the constraints. Gauge fixing and quantization of the model are also briefly discussed. 11 refs

  18. Quantification of three-dimensional cell-mediated collagen remodeling using graph theory.

    Science.gov (United States)

    Bilgin, Cemal Cagatay; Lund, Amanda W; Can, Ali; Plopper, George E; Yener, Bülent

    2010-09-30

    Cell cooperation is a critical event during tissue development. We present the first precise metrics to quantify the interaction between mesenchymal stem cells (MSCs) and extra cellular matrix (ECM). In particular, we describe cooperative collagen alignment process with respect to the spatio-temporal organization and function of mesenchymal stem cells in three dimensions. We defined two precise metrics: Collagen Alignment Index and Cell Dissatisfaction Level, for quantitatively tracking type I collagen and fibrillogenesis remodeling by mesenchymal stem cells over time. Computation of these metrics was based on graph theory and vector calculus. The cells and their three dimensional type I collagen microenvironment were modeled by three dimensional cell-graphs and collagen fiber organization was calculated from gradient vectors. With the enhancement of mesenchymal stem cell differentiation, acceleration through different phases was quantitatively demonstrated. The phases were clustered in a statistically significant manner based on collagen organization, with late phases of remodeling by untreated cells clustering strongly with early phases of remodeling by differentiating cells. The experiments were repeated three times to conclude that the metrics could successfully identify critical phases of collagen remodeling that were dependent upon cooperativity within the cell population. Definition of early metrics that are able to predict long-term functionality by linking engineered tissue structure to function is an important step toward optimizing biomaterials for the purposes of regenerative medicine.

  19. Quantification of three-dimensional cell-mediated collagen remodeling using graph theory.

    Directory of Open Access Journals (Sweden)

    Cemal Cagatay Bilgin

    2010-09-01

    Full Text Available Cell cooperation is a critical event during tissue development. We present the first precise metrics to quantify the interaction between mesenchymal stem cells (MSCs and extra cellular matrix (ECM. In particular, we describe cooperative collagen alignment process with respect to the spatio-temporal organization and function of mesenchymal stem cells in three dimensions.We defined two precise metrics: Collagen Alignment Index and Cell Dissatisfaction Level, for quantitatively tracking type I collagen and fibrillogenesis remodeling by mesenchymal stem cells over time. Computation of these metrics was based on graph theory and vector calculus. The cells and their three dimensional type I collagen microenvironment were modeled by three dimensional cell-graphs and collagen fiber organization was calculated from gradient vectors. With the enhancement of mesenchymal stem cell differentiation, acceleration through different phases was quantitatively demonstrated. The phases were clustered in a statistically significant manner based on collagen organization, with late phases of remodeling by untreated cells clustering strongly with early phases of remodeling by differentiating cells. The experiments were repeated three times to conclude that the metrics could successfully identify critical phases of collagen remodeling that were dependent upon cooperativity within the cell population.Definition of early metrics that are able to predict long-term functionality by linking engineered tissue structure to function is an important step toward optimizing biomaterials for the purposes of regenerative medicine.

  20. The contribution of particle swarm optimization to three-dimensional slope stability analysis.

    Science.gov (United States)

    Kalatehjari, Roohollah; Rashid, Ahmad Safuan A; Ali, Nazri; Hajihassani, Mohsen

    2014-01-01

    Over the last few years, particle swarm optimization (PSO) has been extensively applied in various geotechnical engineering including slope stability analysis. However, this contribution was limited to two-dimensional (2D) slope stability analysis. This paper applied PSO in three-dimensional (3D) slope stability problem to determine the critical slip surface (CSS) of soil slopes. A detailed description of adopted PSO was presented to provide a good basis for more contribution of this technique to the field of 3D slope stability problems. A general rotating ellipsoid shape was introduced as the specific particle for 3D slope stability analysis. A detailed sensitivity analysis was designed and performed to find the optimum values of parameters of PSO. Example problems were used to evaluate the applicability of PSO in determining the CSS of 3D slopes. The first example presented a comparison between the results of PSO and PLAXI-3D finite element software and the second example compared the ability of PSO to determine the CSS of 3D slopes with other optimization methods from the literature. The results demonstrated the efficiency and effectiveness of PSO in determining the CSS of 3D soil slopes.

  1. The Contribution of Particle Swarm Optimization to Three-Dimensional Slope Stability Analysis

    Science.gov (United States)

    A Rashid, Ahmad Safuan; Ali, Nazri

    2014-01-01

    Over the last few years, particle swarm optimization (PSO) has been extensively applied in various geotechnical engineering including slope stability analysis. However, this contribution was limited to two-dimensional (2D) slope stability analysis. This paper applied PSO in three-dimensional (3D) slope stability problem to determine the critical slip surface (CSS) of soil slopes. A detailed description of adopted PSO was presented to provide a good basis for more contribution of this technique to the field of 3D slope stability problems. A general rotating ellipsoid shape was introduced as the specific particle for 3D slope stability analysis. A detailed sensitivity analysis was designed and performed to find the optimum values of parameters of PSO. Example problems were used to evaluate the applicability of PSO in determining the CSS of 3D slopes. The first example presented a comparison between the results of PSO and PLAXI-3D finite element software and the second example compared the ability of PSO to determine the CSS of 3D slopes with other optimization methods from the literature. The results demonstrated the efficiency and effectiveness of PSO in determining the CSS of 3D soil slopes. PMID:24991652

  2. The Contribution of Particle Swarm Optimization to Three-Dimensional Slope Stability Analysis

    Directory of Open Access Journals (Sweden)

    Roohollah Kalatehjari

    2014-01-01

    Full Text Available Over the last few years, particle swarm optimization (PSO has been extensively applied in various geotechnical engineering including slope stability analysis. However, this contribution was limited to two-dimensional (2D slope stability analysis. This paper applied PSO in three-dimensional (3D slope stability problem to determine the critical slip surface (CSS of soil slopes. A detailed description of adopted PSO was presented to provide a good basis for more contribution of this technique to the field of 3D slope stability problems. A general rotating ellipsoid shape was introduced as the specific particle for 3D slope stability analysis. A detailed sensitivity analysis was designed and performed to find the optimum values of parameters of PSO. Example problems were used to evaluate the applicability of PSO in determining the CSS of 3D slopes. The first example presented a comparison between the results of PSO and PLAXI-3D finite element software and the second example compared the ability of PSO to determine the CSS of 3D slopes with other optimization methods from the literature. The results demonstrated the efficiency and effectiveness of PSO in determining the CSS of 3D soil slopes.

  3. Cell-free DNA in a three-dimensional spheroid cell culture model

    DEFF Research Database (Denmark)

    Aucamp, Janine; Calitz, Carlemi; Bronkhorst, Abel J.

    2017-01-01

    Background Investigating the biological functions of cell-free DNA (cfDNA) is limited by the interference of vast numbers of putative sources and causes of DNA release into circulation. Utilization of three-dimensional (3D) spheroid cell cultures, models with characteristics closer to the in vivo...... cultures can serve as effective, simplified in vivo-simulating “closed-circuit” models since putative sources of cfDNA are limited to only the targeted cells. In addition, cfDNA can also serve as an alternative or auxiliary marker for tracking spheroid growth, development and culture stability. Biological...... significance 3D cell cultures can be used to translate “closed-circuit” in vitro model research into data that is relevant for in vivo studies and clinical applications. In turn, the utilization of cfDNA during 3D culture research can optimize sample collection without affecting the stability of the growth...

  4. Energy analysis of four dimensional extended hyperbolic Scarf I plus three dimensional separable trigonometric noncentral potentials using SUSY QM approach

    International Nuclear Information System (INIS)

    Suparmi, A.; Cari, C.; Deta, U. A.; Handhika, J.

    2016-01-01

    The non-relativistic energies and wave functions of extended hyperbolic Scarf I plus separable non-central shape invariant potential in four dimensions are investigated using Supersymmetric Quantum Mechanics (SUSY QM) Approach. The three dimensional separable non-central shape invariant angular potential consists of trigonometric Scarf II, Manning Rosen and Poschl-Teller potentials. The four dimensional Schrodinger equation with separable shape invariant non-central potential is reduced into four one dimensional Schrodinger equations through variable separation method. By using SUSY QM, the non-relativistic energies and radial wave functions are obtained from radial Schrodinger equation, the orbital quantum numbers and angular wave functions are obtained from angular Schrodinger equations. The extended potential means there is perturbation terms in potential and cause the decrease in energy spectra of Scarf I potential. (paper)

  5. Embryonic stem cells in scaffold-free three-dimensional cell culture: osteogenic differentiation and bone generation.

    Science.gov (United States)

    Handschel, Jörg; Naujoks, Christian; Depprich, Rita; Lammers, Lydia; Kübler, Norbert; Meyer, Ulrich; Wiesmann, Hans-Peter

    2011-07-14

    Extracorporeal formation of mineralized bone-like tissue is still an unsolved challenge in tissue engineering. Embryonic stem cells may open up new therapeutic options for the future and should be an interesting model for the analysis of fetal organogenesis. Here we describe a technique for culturing embryonic stem cells (ESCs) in the absence of artificial scaffolds which generated mineralized miromasses. Embryonic stem cells were harvested and osteogenic differentiation was stimulated by the addition of dexamethasone, ascorbic acid, and ß-glycerolphosphate (DAG). After three days of cultivation microspheres were formed. These spherical three-dimensional cell units showed a peripheral zone consisting of densely packed cell layers surrounded by minerals that were embedded in the extracellular matrix. Alizarine red staining confirmed evidence of mineralization after 10 days of DAG stimulation in the stimulated but not in the control group. Transmission electron microscopy demonstrated scorching crystallites and collagenous fibrils as early indication of bone formation. These extracellular structures resembled hydroxyl apatite-like crystals as demonstrated by distinct diffraction patterns using electron diffraction analysis. The micromass culture technique is an appropriate model to form three-dimensional bone-like micro-units without the need for an underlying scaffold. Further studies will have to show whether the technique is applicable also to pluripotent stem cells of different origin. © 2011 Handschel et al; licensee BioMed Central Ltd.

  6. Embryonic stem cells in scaffold-free three-dimensional cell culture: osteogenic differentiation and bone generation

    Directory of Open Access Journals (Sweden)

    Meyer Ulrich

    2011-07-01

    Full Text Available Abstract Extracorporeal formation of mineralized bone-like tissue is still an unsolved challenge in tissue engineering. Embryonic stem cells may open up new therapeutic options for the future and should be an interesting model for the analysis of fetal organogenesis. Here we describe a technique for culturing embryonic stem cells (ESCs in the absence of artificial scaffolds which generated mineralized miromasses. Embryonic stem cells were harvested and osteogenic differentiation was stimulated by the addition of dexamethasone, ascorbic acid, and ß-glycerolphosphate (DAG. After three days of cultivation microspheres were formed. These spherical three-dimensional cell units showed a peripheral zone consisting of densely packed cell layers surrounded by minerals that were embedded in the extracellular matrix. Alizarine red staining confirmed evidence of mineralization after 10 days of DAG stimulation in the stimulated but not in the control group. Transmission electron microscopy demonstrated scorching crystallites and collagenous fibrils as early indication of bone formation. These extracellular structures resembled hydroxyl apatite-like crystals as demonstrated by distinct diffraction patterns using electron diffraction analysis. The micromass culture technique is an appropriate model to form three-dimensional bone-like micro-units without the need for an underlying scaffold. Further studies will have to show whether the technique is applicable also to pluripotent stem cells of different origin.

  7. Canonical quantization of a relativistic particle with curvature and torsion

    International Nuclear Information System (INIS)

    Nesterenko, V.V.

    1991-01-01

    A generalization of the relativistic particle action is considered. It contain, in addition to the length of the world trajectory, the integrals along the world curve of its curvature and torsion. The generalized Hamiltonian formalism for this model in the D-dimensional space-time is constructed. A complete set of the constraints in the phase space is obtained and their division into the first-class and the second-class constraints is accomplished. On this basis the canonical quantization of the model is fulfilled. For D=3 the mass spectrum is obtained in the sector without tachyonic states, the mass of the state being dependent on its spin. It is shown that in the framework of this model when D=3 the possibility to describe the states with integral, half-odd-integral and continuous spins is derived. Interaction with an external Abelian gauge field introduced in the geometrical way. 21 refs

  8. Three dimensional electrostatic solitary waves in a dense magnetoplasma with relativistically degenerate electrons

    Energy Technology Data Exchange (ETDEWEB)

    Ata-ur-Rahman,; Qamar, A. [Institute of Physics and Electronics, University of Peshawar, Peshawar 25000 (Pakistan); National Centre for Physics, QAU Campus, Shahdrah Valley Road, Islamabad 44000 (Pakistan); Masood, W. [National Centre for Physics, QAU Campus, Shahdrah Valley Road, Islamabad 44000 (Pakistan); COMSATS, Institute of Information Technology, Park Road, Chak Shahzad, Islamabad 44000 (Pakistan); Eliasson, B. [Physics Department, University of Strathclyde, Glasgow G4 0NG, Scotland (United Kingdom)

    2013-09-15

    In this paper, small but finite amplitude electrostatic solitary waves in a relativistic degenerate magnetoplasma, consisting of relativistically degenerate electrons and non-degenerate cold ions, are investigated. The Zakharov-Kuznetsov equation is derived employing the reductive perturbation technique and its solitary wave solution is analyzed. It is shown that only compressive electrostatic solitary structures can propagate in such a degenerate plasma system. The effects of plasma number density, ion cyclotron frequency, and direction cosines on the profiles of ion acoustic solitary waves are investigated and discussed at length. The relevance of the present investigation vis-a-vis pulsating white dwarfs is also pointed out.

  9. Multi-particle three-dimensional coordinate estimation in real-time optical manipulation

    DEFF Research Database (Denmark)

    Dam, Jeppe Seidelin; Perch-Nielsen, Ivan R.; Palima, Darwin

    2009-01-01

    We have previously shown how stereoscopic images can be obtained in our three-dimensional optical micromanipulation system [J. S. Dam et al, Opt. Express 16, 7244 (2008)]. Here, we present an extension and application of this principle to automatically gather the three-dimensional coordinates for...

  10. Three-dimensional features on oscillating microbubbles streaming flows

    Science.gov (United States)

    Rossi, Massimiliano; Marin, Alvaro G.; Wang, Cheng; Hilgenfeldt, Sascha; Kähler, Christian J.

    2013-11-01

    Ultrasound-driven oscillating micro-bubbles have been used as active actuators in microfluidic devices to perform manifold tasks such as mixing, sorting and manipulation of microparticles. A common configuration consists in side-bubbles, created by trapping air pockets in blind channels perpendicular to the main channel direction. This configuration results in bubbles with a semi-cylindrical shape that creates a streaming flow generally considered quasi two-dimensional. However, recent experiments performed with three-dimensional velocimetry methods have shown how microparticles can present significant three-dimensional trajectories, especially in regions close to the bubble interface. Several reasons will be discussed such as boundary effects of the bottom/top wall, deformation of the bubble interface leading to more complex vibrational modes, or bubble-particle interactions. In the present investigation, precise measurements of particle trajectories close to the bubble interface will be performed by means of 3D Astigmatic Particle Tracking Velocimetry. The results will allow us to characterize quantitatively the three-dimensional features of the streaming flow and to estimate its implications in practical applications as particle trapping, sorting or mixing.

  11. Spinor and isospinor structure of relativistic particle propagators

    International Nuclear Information System (INIS)

    Gitman, D.M.; Shvartsman, Sh.M.

    1993-07-01

    Representations by means of path integrals are used to find spinor and isospinor structure of relativistic particle propagators in external fields. For Dirac propagator in an external electromagnetic field all Grassmannian integrations are performed and a general result is presented via a bosonic path integral. The spinor structure of the integrand is given explicitly by its decomposition in the independent γ-matrix structures. A similar technique is used to get the isospinor structure of the scalar particle propagator in an external non-Abelian field. (author). 21 refs

  12. Design of a neutral three-dimensional electro-Fenton system with foam nickel as particle electrodes for wastewater treatment

    International Nuclear Information System (INIS)

    Liu, Wei; Ai, Zhihui; Zhang, Lizhi

    2012-01-01

    Highlights: ► Remove RhB by a novel 3D-E-Fenton system using foam nickel as particle electrodes. ► The 3D-E-Fenton system exhibit much higher RhB removal efficiency than the counterpart 3D-E and E-Fenton system. ► Foam nickel as a particle electrode displays good oxygen reduction activity. ► The performance of RhB removal was optimized by some operating parameters and the optimization pH was the neutral. - Abstract: In this work, we demonstrate a novel three-dimensional electro-Fenton system (3D-E-Fenton) for wastewater treatment with foam nickel, activated carbon fiber and Ti/RuO 2 –IrO 2 as the particle electrodes, the cathode, and the anode respectively. This 3D-E-Fenton system could exhibit much higher rhodamine B removal efficiency (99%) than the counterpart three-dimensional electrochemical system (33%) and E-Fenton system (19%) at neutral pH in 30 min. The degradation efficiency enhancement was attributed to much more hydroxyl radicals generated in the 3D-E-Fenton system because foam nickel particle electrodes could activate molecular oxygen to produce ·O 2 − via a single-electron transfer pathway to subsequently generate more H 2 O 2 and hydroxyl radicals. This is the first observation of molecular oxygen activation over the particle electrodes in the three-dimensional electrochemical system. These interesting findings could provide some new insight on the development of high efficient E-Fenton system for wastewater treatment at neutral pH.

  13. A NEW MULTI-DIMENSIONAL GENERAL RELATIVISTIC NEUTRINO HYDRODYNAMICS CODE FOR CORE-COLLAPSE SUPERNOVAE. II. RELATIVISTIC EXPLOSION MODELS OF CORE-COLLAPSE SUPERNOVAE

    Energy Technology Data Exchange (ETDEWEB)

    Mueller, Bernhard; Janka, Hans-Thomas; Marek, Andreas, E-mail: bjmuellr@mpa-garching.mpg.de, E-mail: thj@mpa-garching.mpg.de [Max-Planck-Institut fuer Astrophysik, Karl-Schwarzschild-Str. 1, D-85748 Garching (Germany)

    2012-09-01

    We present the first two-dimensional general relativistic (GR) simulations of stellar core collapse and explosion with the COCONUT hydrodynamics code in combination with the VERTEX solver for energy-dependent, three-flavor neutrino transport, using the extended conformal flatness condition for approximating the space-time metric and a ray-by-ray-plus ansatz to tackle the multi-dimensionality of the transport. For both of the investigated 11.2 and 15 M{sub Sun} progenitors we obtain successful, though seemingly marginal, neutrino-driven supernova explosions. This outcome and the time evolution of the models basically agree with results previously obtained with the PROMETHEUS hydro solver including an approximative treatment of relativistic effects by a modified Newtonian potential. However, GR models exhibit subtle differences in the neutrinospheric conditions compared with Newtonian and pseudo-Newtonian simulations. These differences lead to significantly higher luminosities and mean energies of the radiated electron neutrinos and antineutrinos and therefore to larger energy-deposition rates and heating efficiencies in the gain layer with favorable consequences for strong nonradial mass motions and ultimately for an explosion. Moreover, energy transfer to the stellar medium around the neutrinospheres through nucleon recoil in scattering reactions of heavy-lepton neutrinos also enhances the mentioned effects. Together with previous pseudo-Newtonian models, the presented relativistic calculations suggest that the treatment of gravity and energy-exchanging neutrino interactions can make differences of even 50%-100% in some quantities and is likely to contribute to a finally successful explosion mechanism on no minor level than hydrodynamical differences between different dimensions.

  14. Measuring the cosmological background of relativistic particles with WMAP

    CERN Document Server

    Crotty, P; Pastor, S; Crotty, Patrick; Lesgourgues, Julien; Pastor, Sergio

    2003-01-01

    We show that the first year results of the Wilkinson Microwave Anisotropy Probe (WMAP) constrain very efficiently the energy density in relativistic particles in the universe. We derive new bounds on additional relativistic degrees of freedom expressed in terms of an excess in the effective number of light neutrinos Delta N_eff. Within the flat LambdaCDM scenario, the allowed range is Delta N_eff < 6 (95% CL) using WMAP data only, or -2.6 < Delta N_eff < 4 with the prior H_0= 72 \\pm 8 km/s/Mpc. When other cosmic microwave background and large scale structure experiments are taken into account, the window shrinks to -1.5 < Delta N_eff < 4.2. These results are in perfect agreement with the bounds from primordial nucleosynthesis. Non-minimal cosmological models with extra relativistic degrees of freedom are now severely restricted.

  15. Evaluation of the osteogenic differentiation of gingiva-derived stem cells grown on culture plates or in stem cell spheroids: Comparison of two- and three-dimensional cultures.

    Science.gov (United States)

    Lee, Sung-Il; Ko, Youngkyung; Park, Jun-Beom

    2017-09-01

    Three-dimensional cell culture systems provide a convenient in vitro model for the study of complex cell-cell and cell-matrix interactions in the absence of exogenous substrates. The current study aimed to evaluate the osteogenic differentiation potential of gingiva-derived stem cells cultured in two-dimensional or three-dimensional systems. To the best of our knowledge, the present study is the first to compare the growth of gingiva-derived stem cells in monolayer culture to a three-dimensional culture system with microwells. For three-dimensional culture, gingiva-derived stem cells were isolated and seeded into polydimethylsiloxane-based concave micromolds. Alkaline phosphatase activity and alizarin red S staining assays were then performed to evaluate osteogenesis and the degree of mineralization, respectively. Stem cell spheroids had a significantly increased level of alkaline phosphatase activity and mineralization compared with cells from the two-dimensional culture. In addition, an increase in mineralized deposits was observed with an increase in the loading cell number. The results of present study indicate that gingiva-derived stem cell spheroids exhibit an increased osteogenic potential compared with stem cells from two-dimensional culture. This highlights the potential of three-dimensional culture systems using gingiva-derived stem cells for regenerative medicine applications requiring stem cells with osteogenic potential.

  16. Classical many-body problems amenable to exact treatments (solvable and/or integrable and/or linearizable...) in one-, two- and three-dimensional space

    CERN Document Server

    Calogero, Francesco

    2001-01-01

    This book focuses on exactly treatable classical (i.e. non-quantal non-relativistic) many-body problems, as described by Newton's equation of motion for mutually interacting point particles. Most of the material is based on the author's research and is published here for the first time in book form. One of the main novelties is the treatment of problems in two- and three-dimensional space. Many related techniques are presented, e.g. the theory of generalized Lagrangian-type interpolation in higher-dimensional spaces. This book is written for students as well as for researchers; it works out detailed examples before going on to treat more general cases. Many results are presented via exercises, with clear hints pointing to their solutions.

  17. Extended Galilean symmetries of non-relativistic strings

    Energy Technology Data Exchange (ETDEWEB)

    Batlle, Carles [Departament de Matemàtiques and IOC, Universitat Politècnica de Catalunya, EPSEVG,Av. V. Balaguer 1, E-08808 Vilanova i la Geltrú (Spain); Gomis, Joaquim; Not, Daniel [Departament de Física Quàntica i Astrofísica and Institut de Ciències del Cosmos (ICCUB),Universitat de Barcelona,Martí i Franquès 1, E-08028 Barcelona (Spain)

    2017-02-09

    We consider two non-relativistic strings and their Galilean symmetries. These strings are obtained as the two possible non-relativistic (NR) limits of a relativistic string. One of them is non-vibrating and represents a continuum of non-relativistic massless particles, and the other one is a non-relativistic vibrating string. For both cases we write the generator of the most general point transformation and impose the condition of Noether symmetry. As a result we obtain two sets of non-relativistic Killing equations for the vector fields that generate the symmetry transformations. Solving these equations shows that NR strings exhibit two extended, infinite dimensional space-time symmetries which contain, as a subset, the Galilean symmetries. For each case, we compute the associated conserved charges and discuss the existence of non-central extensions.

  18. Review of multi-dimensional large-scale kinetic simulation and physics validation of ion acceleration in relativistic laser-matter interaction

    International Nuclear Information System (INIS)

    Wu, Hui-Chun; Hegelich, B.M.; Fernandez, J.C.; Shah, R.C.; Palaniyappan, S.; Jung, D.; Yin, L.; Albright, B.J.; Bowers, K.; Kwan, T.J.

    2012-01-01

    Two new experimental technologies enabled realization of Break-out afterburner (BOA) - High quality Trident laser and free-standing C nm-targets. VPIC is an powerful tool for fundamental research of relativistic laser-matter interaction. Predictions from VPIC are validated - Novel BOA and Solitary ion acceleration mechanisms. VPIC is a fully explicit Particle In Cell (PIC) code: models plasma as billions of macro-particles moving on a computational mesh. VPIC particle advance (which typically dominates computation) has been optimized extensively for many different supercomputers. Laser-driven ions lead to realization promising applications - Ion-based fast ignition; active interrogation, hadron therapy.

  19. Particle-in-cell simulations on spontaneous thermal magnetic field fluctuations

    Energy Technology Data Exchange (ETDEWEB)

    Simões, F. J. R. Jr.; Pavan, J. [Instituto de Física e Matemática, UFPel, Pelotas, RS (Brazil); Gaelzer, R.; Ziebell, L. F. [Instituto de Física, UFRGS, Porto Alegre, RS (Brazil); Yoon, P. H. [Institute for Physical Science and Technology, University of Maryland, College Park, Maryland 20742 (United States)

    2013-10-15

    In this paper an electromagnetic particle code is used to investigate the spontaneous thermal emission. Specifically we perform particle-in-cell simulations employing a non-relativistic isotropic Maxwellian particle distribution to show that thermal fluctuations are related to the origin of spontaneous magnetic field fluctuation. These thermal fluctuations can become seed for further amplification mechanisms and thus be considered at the origin of the cosmological magnetic field, at microgauss levels. Our numerical results are in accordance with theoretical results presented in the literature.

  20. Three-Dimensional Design of a Non-Axisymmetric Periodic Permanent Magnet Focusing System

    CERN Document Server

    Chen Chi Ping; Radovinsky, Alexey; Zhou, Jing

    2005-01-01

    A three-dimensional (3D) design is presented of a non-axisymmetric periodic permanent magnet focusing system which will be used to focus a large-aspect-ratio, ellipse-shaped, space-charge-dominated electron beam. In this design, an analytic theory is used to specify the magnetic profile for beam transport. The OPERA3D code is used to compute and optimize a realizable magnet system. Results of the magnetic design are verified by two-dimensional particle-in-cell and three-dimensional trajectory simulations of beam propagation using PFB2D and OMNITRAK, respectively. Results of fabrication tolerance studies are discussed.

  1. Design and development of the associated-particle three-dimensional imaging technique

    International Nuclear Information System (INIS)

    Ussery, L.E.; Hollas, C.L.

    1994-10-01

    The authors describe the development of the ''associated-particle'' imaging technique for producing low-resolution three-dimensional images of objects. Based on the t(d,n) 4 He reaction, the method requires access to only one side of the object being imaged and allows for the imaging of individual chemical elements in the material under observation. Studies were performed to (1) select the appropriate components of the system, including detectors, data-acquisition electronics, and neutron source, and (2) optimize experimental methods for collection and presentation of data. This report describes some of the development steps involved and provides a description of the complete final system that was developed

  2. Three-dimensional printing of stem cell-laden hydrogels submerged in a hydrophobic high-density fluid

    International Nuclear Information System (INIS)

    Duarte Campos, Daniela F; Blaeser, Andreas; Weber, Michael; Fischer, Horst; Jäkel, Jörg; Neuss, Sabine; Jahnen-Dechent, Wilhelm

    2013-01-01

    Over the last decade, bioprinting technologies have begun providing important tissue engineering strategies for regenerative medicine and organ transplantation. The major drawback of past approaches has been poor or inadequate material-printing device and substrate combinations, as well as the relatively small size of the printed construct. Here, we hypothesise that cell-laden hydrogels can be printed when submerged in perfluorotributylamine (C 12 F 27 N), a hydrophobic high-density fluid, and that these cells placed within three-dimensional constructs remain viable allowing for cell proliferation and production of extracellular matrix. Human mesenchymal stem cells and MG-63 cells were encapsulated into agarose hydrogels, and subsequently printed in high aspect ratio in three dimensional structures that were supported in high density fluorocarbon. Three-dimensional structures with various shapes and sizes were manufactured and remained stable for more than six months. Live/dead and DAPI stainings showed viable cells 24 h after the printing process, as well as after 21 days in culture. Histological and immunohistochemical analyses after 14 and 21 days revealed viable cells with marked matrix production and signs of proliferation. The compressive strength values of the printed gels consequently increased during the two weeks in culture, revealing encouraging results for future applications in regenerative medicine. (paper)

  3. Multi-dimensional relativistic simulations of core-collapse supernovae with energy-dependent neutrino transport

    International Nuclear Information System (INIS)

    Mueller, Bernhard

    2009-01-01

    In this thesis, we have presented the first multi-dimensional models of core-collapse supernovae that combine a detailed, up-to-date treatment of neutrino transport, the equation of state, and - in particular - general relativistic gravity. Building on the well-tested neutrino transport code VERTEX and the GR hydrodynamics code CoCoNuT, we developed and implemented a relativistic generalization of a ray-by-ray-plus method for energy-dependent neutrino transport. The result of these effort, the VERTEX-CoCoNuT code, also incorporates a number of improved numerical techniques that have not been used in the code components VERTEX and CoCoNuT before. In order to validate the VERTEX-CoCoNuT code, we conducted several test simulations in spherical symmetry, most notably a comparison with the one-dimensional relativistic supernova code AGILE-BOLTZTRAN and the Newtonian PROMETHEUSVERTEX code. (orig.)

  4. Multi-dimensional relativistic simulations of core-collapse supernovae with energy-dependent neutrino transport

    Energy Technology Data Exchange (ETDEWEB)

    Mueller, Bernhard

    2009-05-07

    In this thesis, we have presented the first multi-dimensional models of core-collapse supernovae that combine a detailed, up-to-date treatment of neutrino transport, the equation of state, and - in particular - general relativistic gravity. Building on the well-tested neutrino transport code VERTEX and the GR hydrodynamics code CoCoNuT, we developed and implemented a relativistic generalization of a ray-by-ray-plus method for energy-dependent neutrino transport. The result of these effort, the VERTEX-CoCoNuT code, also incorporates a number of improved numerical techniques that have not been used in the code components VERTEX and CoCoNuT before. In order to validate the VERTEX-CoCoNuT code, we conducted several test simulations in spherical symmetry, most notably a comparison with the one-dimensional relativistic supernova code AGILE-BOLTZTRAN and the Newtonian PROMETHEUSVERTEX code. (orig.)

  5. Three-body unitarity with isobars revisited

    Energy Technology Data Exchange (ETDEWEB)

    Mai, M.; Hu, B. [The George Washington University, Washington, DC (United States); Doering, M. [The George Washington University, Washington, DC (United States); Thomas Jefferson National Accelerator Facility, Newport News, VA (United States); Pilloni, A. [Thomas Jefferson National Accelerator Facility, Newport News, VA (United States); Szczepaniak, A. [Thomas Jefferson National Accelerator Facility, Newport News, VA (United States); Indiana University, Center for Exploration of Energy and Matter, Bloomington, IN (United States); Indiana University, Physics Department, Bloomington, IN (United States)

    2017-09-15

    The particle exchange model of hadron interactions can be used to describe three-body scattering under the isobar assumption. In this study we start from the 3 → 3 scattering amplitude for spinless particles, which contains an isobar-spectator scattering amplitude. Using a Bethe-Salpeter Ansatz for the latter, we derive a relativistic three-dimensional scattering equation that manifestly fulfills three-body unitarity and two-body unitarity for the sub-amplitudes. This property holds for energies above breakup and also in the presence of resonances in the sub-amplitudes. (orig.)

  6. Four-dimensional optical manipulation of colloidal particles

    DEFF Research Database (Denmark)

    Rodrigo, P.J.; Daria, V.R.; Glückstad, J.

    2005-01-01

    We transform a TEM00 laser mode into multiple counterpropagating optical traps to achieve four-dimensional simultaneous manipulation of multiple particles. Efficient synthesis and dynamic control of the counterpropagating-beam traps is carried out via the generalized phase contrast method......, and a spatial polarization-encoding scheme. Our experiments genuinely demonstrate real-time, interactive particle-position control for forming arbitrary volumetric constellations and complex three-dimensional trajectories of multiple particles. This opens up doors for cross-disciplinary cutting-edge research...

  7. Relativistic Spinning Particle without Grassmann Variables and the Dirac Equation

    Directory of Open Access Journals (Sweden)

    A. A. Deriglazov

    2011-01-01

    Full Text Available We present the relativistic particle model without Grassmann variables which, being canonically quantized, leads to the Dirac equation. Classical dynamics of the model is in correspondence with the dynamics of mean values of the corresponding operators in the Dirac theory. Classical equations for the spin tensor are the same as those of the Barut-Zanghi model of spinning particle.

  8. Relativistic alpha-particles emitted in Fe-emulsion interactions at 1.7 A GeV

    International Nuclear Information System (INIS)

    Bhalla, K.B.; Chaudhry, M.; Lokanathan, S.; Grover, R.K.; Daftari, I.K.; Mangotra, L.L.; Rao, N.K.; Garpman, S.; Otterlund, I.

    1981-02-01

    Relativistic α-particles have been studied in 423 Fe-emulsion interactions at 1.7 A Gev. Comparisons of the observed angular distribution with that from 16 O-emulsion reactions at 2.1 A GeV reveal that more α particles are observed at large angles in the Fe-emulsion reactions. The α particles with large angles connot be explained by fragmentation from a clean cut spectator. Comparison of the experimental data with moving relativistic Boltzmann distributions shows that a single Boltzmann distribution cannot fit the fragmentation peak and the tail simultaneously. A thermal source (fireball) explaining the tail part of the distribution need to be formed by a mechanism other than simple clean cut participant-spectator picture. A large transverse momentum transfer to spectator before fragmentation may explain the tail. (author)

  9. Imaging of cellular spread on a three-dimensional scaffold by means of a novel cell-labeling technique for high-resolution computed tomography.

    Science.gov (United States)

    Thimm, Benjamin W; Hofmann, Sandra; Schneider, Philipp; Carretta, Roberto; Müller, Ralph

    2012-03-01

    Computed tomography (CT) represents a truly three-dimensional (3D) imaging technique that can provide high-resolution images on the cellular level. Thus, one approach to detect single cells is X-ray absorption-based CT, where cells are labeled with a dense, opaque material providing the required contrast for CT imaging. Within the present work, a novel cell-labeling method has been developed showing the feasibility of labeling fixed cells with iron oxide (FeO) particles for subsequent CT imaging and quantitative morphometry. A biotin-streptavidin detection system was exploited to bind FeO particles to its target endothelial cells. The binding of the particles was predominantly close to the cell centers on 2D surfaces as shown by light microscopy, scanning electron microscopy, and CT. When cells were cultured on porous, 3D polyurethane surfaces, significantly more FeO particles were detected compared with surfaces without cells and FeO particle labeling using CT. Here, we report on the implementation and evaluation of a novel cell detection method based on high-resolution CT. This system has potential in cell tracking for 3D in vitro imaging in the future.

  10. Effective potentials of the relativistic three-body problem with electromagnetic interaction in adiabatic approximation

    International Nuclear Information System (INIS)

    Bakalov, D.D.; Melezhik, V.S.

    1987-01-01

    The relativistic Hamiltonian for 3-spin particles with electromagnetic interaction has been represented in the form of a sum of terms with factorized dependence on spin, angular and spheroidal variable, and its matrix elements have been expressed in terms of the matrix elements of a small number of ''basic'' operators. The numerical values of the latter have been tabulated, thus allowing for the evaluation of the leading relativistic effects in any 3-body system (with unit particle charge) with and accuracy of ∼ 0(1/2M), where 1/2M=(M 1 -1 +M 2 -1 )/2(M 1 -1 +M 3 -1 ) is the small parameter of the adiabatic expansion (M i , i=1,2,3 being particle masses)

  11. Quantitative volumetric Raman imaging of three dimensional cell cultures

    Science.gov (United States)

    Kallepitis, Charalambos; Bergholt, Mads S.; Mazo, Manuel M.; Leonardo, Vincent; Skaalure, Stacey C.; Maynard, Stephanie A.; Stevens, Molly M.

    2017-03-01

    The ability to simultaneously image multiple biomolecules in biologically relevant three-dimensional (3D) cell culture environments would contribute greatly to the understanding of complex cellular mechanisms and cell-material interactions. Here, we present a computational framework for label-free quantitative volumetric Raman imaging (qVRI). We apply qVRI to a selection of biological systems: human pluripotent stem cells with their cardiac derivatives, monocytes and monocyte-derived macrophages in conventional cell culture systems and mesenchymal stem cells inside biomimetic hydrogels that supplied a 3D cell culture environment. We demonstrate visualization and quantification of fine details in cell shape, cytoplasm, nucleus, lipid bodies and cytoskeletal structures in 3D with unprecedented biomolecular specificity for vibrational microspectroscopy.

  12. Magnetic Field Generation, Particle Energization and Radiation at Relativistic Shear Boundary Layers

    Science.gov (United States)

    Liang, Edison; Fu, Wen; Spisak, Jake; Boettcher, Markus

    2015-11-01

    Recent large scale Particle-in-Cell (PIC) simulations have demonstrated that in unmagnetized relativistic shear flows, strong transverse d.c. magnetic fields are generated and sustained by ion-dominated currents on the opposite sides of the shear interface. Instead of dissipating the shear flow free energy via turbulence formation and mixing as it is usually found in MHD simulations, the kinetic results show that the relativistic boundary layer stabilizes itself via the formation of a robust vacuum gap supported by a strong magnetic field, which effectively separates the opposing shear flows, as in a maglev train. Our new PIC simulations have extended the runs to many tens of light crossing times of the simulation box. Both the vacuum gap and supporting magnetic field remain intact. The electrons are energized to reach energy equipartition with the ions, with 10% of the total energy in electromagnetic fields. The dominant radiation mechanism is similar to that of a wiggler, due to oscillating electron orbits around the boundary layer.

  13. BRST field theory of relativistic particles

    International Nuclear Information System (INIS)

    Holten, J.W. van

    1992-01-01

    A generalization of BRST field theory is presented, based on wave operators for the fields constructed out of, but different from the BRST operator. The authors discuss their quantization, gauge fixing and the derivation of propagators. It is shown, that the generalized theories are relevant to relativistic particle theories in the Brink-Di Vecchia-Howe-Polyakov (BDHP) formulation, and argue that the same phenomenon holds in string theories. In particular it is shown, that the naive BRST formulation of the BDHP theory leads to trivial quantum field theories with vanishing correlation functions. (author). 22 refs

  14. Photospheric Emission from Collapsar Jets in 3D Relativistic Hydrodynamics

    Science.gov (United States)

    Ito, Hirotaka; Matsumoto, Jin; Nagataki, Shigehiro; Warren, Donald C.; Barkov, Maxim V.

    2015-12-01

    We explore the photospheric emission from a relativistic jet breaking out from a massive stellar envelope based on relativistic hydrodynamical simulations and post-process radiation transfer calculations in three dimensions. To investigate the impact of three-dimensional (3D) dynamics on the emission, two models of injection conditions are considered for the jet at the center of the progenitor star: one with periodic precession and another without precession. We show that structures developed within the jet due to the interaction with the stellar envelope, as well as due to the precession, have a significant imprint on the resulting emission. Particularly, we find that the signature of precession activity by the central engine is not smeared out and can be directly observed in the light curve as a periodic signal. We also show that non-thermal features, which can account for observations of gamma-ray bursts, are produced in the resulting spectra even though only thermal photons are injected initially and the effect of non-thermal particles is not considered.

  15. Focusing peculiarities of ion-channel guiding on a relativistic electron beam in a free-electron laser with a three-dimensional wiggler

    International Nuclear Information System (INIS)

    Ouyang, Zhengbiao; Zhang, Shi-Chang

    2014-01-01

    In a free-electron laser the ‘natural focusing’ effect of a three-dimensional wiggler is too weak to confine the transport of a relativistic electron beam when the beam has a high current and consequently an external focusing system is often needed. In this paper we study the focusing peculiarities of an ion-channel guide field on an electron beam. Nonlinear simulations of an electron beam transport show that, compared to an axial guide magnetic field, the ion-channel guide field results in smaller velocity–space and configuration–space spreads. The intrinsic mechanism of this physical phenomenon is that the ion-channel guide field confines the trajectory of the electron motion resulting in a smaller instantaneous curvature radius and a slighter curvature-center excursion than an axial guide magnetic field does. It is also found that, unlike with an axial guide magnetic field, over-focusing may occur if the ion-channel guide field is too strong. (paper)

  16. Electrospinning PCL Scaffolds Manufacture for Three-Dimensional Breast Cancer Cell Culture

    Directory of Open Access Journals (Sweden)

    Marc Rabionet

    2017-08-01

    Full Text Available In vitro cell culture is traditionally performed within two-dimensional (2D environments, providing a quick and cheap way to study cell properties in a laboratory. However, 2D systems differ from the in vivo environment and may not mimic the physiological cell behavior realistically. For instance, 2D culture models are thought to induce cancer stem cells (CSCs differentiation, a rare cancer cell subpopulation responsible for tumor initiation and relapse. This fact hinders the development of therapeutic strategies for tumors with a high relapse percentage, such as triple negative breast cancer (TNBC. Thus, three-dimensional (3D scaffolds have emerged as an attractive alternative to monolayer culture, simulating the extracellular matrix structure and maintaining the differentiation state of cells. In this work, scaffolds were fabricated through electrospinning different poly(ε-caprolactone-acetone solutions. Poly(ε-caprolactone (PCL meshes were seeded with triple negative breast cancer (TNBC cells and 15% PCL scaffolds displayed significantly (p < 0.05 higher cell proliferation and elongation than the other culture systems. Moreover, cells cultured on PCL scaffolds exhibited higher mammosphere forming capacity and aldehyde dehydrogenase activity than 2D-cultured cells, indicating a breast CSCs enrichment. These results prove the powerful capability of electrospinning technology in terms of poly(ε-caprolactone nanofibers fabrication. In addition, this study has demonstrated that electrospun 15% PCL scaffolds are suitable tools to culture breast cancer cells in a more physiological way and to expand the niche of breast CSCs. In conclusion, three-dimensional cell culture using PCL scaffolds could be useful to study cancer stem cell behavior and may also trigger the development of new specific targets against such malignant subpopulation.

  17. Advective isotope transport by mixing cell and particle tracking algorithms

    International Nuclear Information System (INIS)

    Tezcan, L.; Meric, T.

    1999-01-01

    The 'mixing cell' algorithm of the environmental isotope data evaluation is integrated with the three dimensional finite difference ground water flow model (MODFLOW) to simulate the advective isotope transport and the approach is compared with the 'particle tracking' algorithm of the MOC3D, that simulates three-dimensional solute transport with the method of characteristics technique

  18. Infinite stochastic acceleration of charged particles from non-relativistic initial energies

    International Nuclear Information System (INIS)

    Buts, V.A.; Manujlenko, O.V.; Turkin, Yu.A.

    1997-01-01

    Stochastic charged particle acceleration by electro-magnetic field due to overlapping of non-linear cyclotron resonances is considered. It was shown that non-relativistic charged particles are involved in infinitive stochastic acceleration regime. This effect can be used for stochastic acceleration or for plasma heating by regular electro-magnetic fields

  19. Quantitative volumetric Raman imaging of three dimensional cell cultures

    KAUST Repository

    Kallepitis, Charalambos

    2017-03-22

    The ability to simultaneously image multiple biomolecules in biologically relevant three-dimensional (3D) cell culture environments would contribute greatly to the understanding of complex cellular mechanisms and cell–material interactions. Here, we present a computational framework for label-free quantitative volumetric Raman imaging (qVRI). We apply qVRI to a selection of biological systems: human pluripotent stem cells with their cardiac derivatives, monocytes and monocyte-derived macrophages in conventional cell culture systems and mesenchymal stem cells inside biomimetic hydrogels that supplied a 3D cell culture environment. We demonstrate visualization and quantification of fine details in cell shape, cytoplasm, nucleus, lipid bodies and cytoskeletal structures in 3D with unprecedented biomolecular specificity for vibrational microspectroscopy.

  20. Plasmoid statistics in relativistic magnetic reconnection

    Science.gov (United States)

    Petropoulou, M.; Christie, I. M.; Sironi, L.; Giannios, D.

    2018-04-01

    Plasmoids, overdense blobs of plasma containing magnetic fields and high-energy particles, are a self-consistent outcome of the reconnection process in the relativistic regime. Recent two-dimensional particle-in-cell (PIC) simulations have shown that plasmoids can undergo a variety of processes (e.g. mergers, bulk acceleration, growth, and advection) within the reconnection layer. We developed a Monte Carlo code, benchmarked with the recent PIC simulations, to examine the effects of these processes on the steady-state size and momentum distributions of the plasmoid chain. The differential plasmoid size distribution is shown to be a power law, ranging from a few plasma skin depths to ˜0.1 of the reconnection layer's length. The power-law slope is shown to be linearly dependent upon the ratio of the plasmoid acceleration and growth rates, which slightly decreases with increasing plasma magnetization. We perform a detailed comparison of our results with those of recent PIC simulations and briefly discuss the astrophysical implications of our findings through the representative case of flaring events from blazar jets.

  1. Deep inelastic scaling in nuclear and particle physics

    International Nuclear Information System (INIS)

    West, G.B.

    1988-01-01

    These lectures are intended to be a pedagogical introduction to some of the ideas and concepts concerning scaling phenomena which arise in nuclear and particle physics. Topics discussed are: classical scaling and dimensional analysis; non-relativistic treatment; dynamics and scaling; y-scaling; and relativistic treatment (QCD). 22 refs., 16 figs

  2. photon-plasma: A modern high-order particle-in-cell code

    International Nuclear Information System (INIS)

    Haugbølle, Troels; Frederiksen, Jacob Trier; Nordlund, Åke

    2013-01-01

    We present the photon-plasma code, a modern high order charge conserving particle-in-cell code for simulating relativistic plasmas. The code is using a high order implicit field solver and a novel high order charge conserving interpolation scheme for particle-to-cell interpolation and charge deposition. It includes powerful diagnostics tools with on-the-fly particle tracking, synthetic spectra integration, 2D volume slicing, and a new method to correctly account for radiative cooling in the simulations. A robust technique for imposing (time-dependent) particle and field fluxes on the boundaries is also presented. Using a hybrid OpenMP and MPI approach, the code scales efficiently from 8 to more than 250.000 cores with almost linear weak scaling on a range of architectures. The code is tested with the classical benchmarks particle heating, cold beam instability, and two-stream instability. We also present particle-in-cell simulations of the Kelvin-Helmholtz instability, and new results on radiative collisionless shocks

  3. Reinterpretation of the ''relativistic mass'' correction to the spin magnetic moment of a moving particle

    International Nuclear Information System (INIS)

    Hegstrom, R.A.; Lhuillier, C.

    1977-01-01

    Starting from a classical covariant equation of motion for the spin of a particle moving in a homogeneous electromagnetic field (the Bargmann-Michel-Telegdi equation), we show that the ''relativistic mass'' correction to the electron spin magnetic moment, which has been obtained previously from relativistic quantum-mechanical treatments of the Zeeman effect, may be reinterpreted as the combination of three classical effects: (i) the difference in time scales in the electron rest frame vis-a-vis the lab frame, (ii) the Lorentz transformation of the magnetic field between the two frames, and (iii) the Thomas precession of the electron spin due to the acceleration of the electron produced by the magnetic field

  4. Three-dimensional reconstruction of statistically optimal unit cells of polydisperse particulate composites from microtomography

    International Nuclear Information System (INIS)

    Lee, H.; Brandyberry, M.; Tudor, A.; Matous, K.

    2009-01-01

    In this paper, we present a systematic approach for characterization and reconstruction of statistically optimal representative unit cells of polydisperse particulate composites. Microtomography is used to gather rich three-dimensional data of a packed glass bead system. First-, second-, and third-order probability functions are used to characterize the morphology of the material, and the parallel augmented simulated annealing algorithm is employed for reconstruction of the statistically equivalent medium. Both the fully resolved probability spectrum and the geometrically exact particle shapes are considered in this study, rendering the optimization problem multidimensional with a highly complex objective function. A ten-phase particulate composite composed of packed glass beads in a cylindrical specimen is investigated, and a unit cell is reconstructed on massively parallel computers. Further, rigorous error analysis of the statistical descriptors (probability functions) is presented and a detailed comparison between statistics of the voxel-derived pack and the representative cell is made.

  5. Relativistic local quantum field theory for m=0 particles

    International Nuclear Information System (INIS)

    Morales Villasevil, A.

    1965-01-01

    A method is introduced ta deal with relativistic quantum field theory for particles with m=0. Two mappings I and J, giving rise respectively to particle and anti particle states, are defined between a test space and the physical Hilbert space. The intrinsic field operator is then defined as the minimal causal linear combinations of operators belonging to the annihilation-creation algebra associated to the germ and antigerm parts of the element. Local elements are introduced as improper test elements and local field operators are constructed in the same way as the intrinsic ones. Commutation rules are given. (Author) 17 refs

  6. Design and analysis of a radio frequency extractor in an S-band relativistic klystron amplifier

    Energy Technology Data Exchange (ETDEWEB)

    Zhang Zehai; Zhang Jun; Shu Ting; Qi Zumin [College of Optoelectronic Science and Engineering, National University of Defense Technology, Changsha, Hunan 410073 (China)

    2012-09-15

    A radio frequency (RF) extractor converts the energy of a strongly modulated intense relativistic electron beam (IREB) into the energy of high power microwave in relativistic klystron amplifier (RKA). In the aim of efficiently extracting the energy of the modulated IREB, a RF extractor with all round coupling structure is proposed. Due to the all round structure, the operating transverse magnetic mode can be established easily and its resonant property can be investigated with an approach of group delay time. Furthermore, the external quality factor can be low enough. The design and analysis of the extractor applied in an S-band RKA are carried out, and the performance of the extractor is validated with three-dimensional (3D) particle-in-cell simulations. The extraction efficiency reaches 27% in the simulation with a totally 3D model of the whole RKA. The primary experiments are also carried out and the results show that the RF extractor with the external quality factor of 7.9 extracted 22% of the beam power and transformed it into the high power microwave. Better results are expected after the parasitic mode between the input and middle cavities is suppressed.

  7. Design and analysis of a radio frequency extractor in an S-band relativistic klystron amplifier

    Science.gov (United States)

    Zhang, Zehai; Zhang, Jun; Shu, Ting; Qi, Zumin

    2012-09-01

    A radio frequency (RF) extractor converts the energy of a strongly modulated intense relativistic electron beam (IREB) into the energy of high power microwave in relativistic klystron amplifier (RKA). In the aim of efficiently extracting the energy of the modulated IREB, a RF extractor with all round coupling structure is proposed. Due to the all round structure, the operating transverse magnetic mode can be established easily and its resonant property can be investigated with an approach of group delay time. Furthermore, the external quality factor can be low enough. The design and analysis of the extractor applied in an S-band RKA are carried out, and the performance of the extractor is validated with three-dimensional (3D) particle-in-cell simulations. The extraction efficiency reaches 27% in the simulation with a totally 3D model of the whole RKA. The primary experiments are also carried out and the results show that the RF extractor with the external quality factor of 7.9 extracted 22% of the beam power and transformed it into the high power microwave. Better results are expected after the parasitic mode between the input and middle cavities is suppressed.

  8. Simulation of high-energy particle production through sausage and kink instabilities in pinched plasma discharges

    International Nuclear Information System (INIS)

    Haruki, Takayuki; Yousefi, Hamid Reza; Masugata, Katsumi; Sakai, Jun-Ichi; Mizuguchi, Yusuke; Makino, Nao; Ito, Hiroaki

    2006-01-01

    In an experimental plasma, high-energy particles were observed by using a plasma focus device, to obtain energies of a few hundred keV for electrons, up to MeV for ions. In order to study the mechanism of high-energy particle production in pinched plasma discharges, a numerical simulation was introduced. By use of a three-dimensional relativistic and fully electromagnetic particle-in-cell code, the dynamics of a Z-pinch plasma, thought to be unstable against sausage and kink instabilities, are investigated. In this work, the development of sausage and kink instabilities and subsequent high-energy particle production are shown. In the model used here, cylindrically distributed electrons and ions are driven by an external electric field. The driven particles spontaneously produce a current, which begins to pinch by the Lorentz force. Initially the pinched current is unstable against a sausage instability, and then becomes unstable against a kink instability. As a result high-energy particles are observed

  9. CHARGED PARTICLE MULTIPLICITIES IN ULTRA-RELATIVISTIC AU+AU AND CU+CU COLLISIONS

    Science.gov (United States)

    Back, B. B.; Alver, B.; Back, B. B.; Baker, M. D.; Ballintijn, M.; Barton, D. S.; Betts, R. R.; Bickley, A. A.; Bindel, R.; Busza, W.; Carroll, A.; Chai, Z.; Chetluru, V.; Decowski, M. P.; Garcia, E.; Gburek, T.; George, N.; Gulbrandsen, K.; Halliwell, C.; Hamblen, J.; Harnarine, I.; Hauer, M.; Henderson, C.; Hofman, D. J.; Hollis, R. S.; Holynski, R.; Holzman, B.; Iordanova, A.; Johnson, E.; Kane, J. L.; Khan, N.; Kulinich, P.; Kuo, C. M.; Li, W.; Lin, W. T.; Loizides, C.; Manly, S.; Mignerey, A. C.; Nouicer, R.; Olszewski, A.; Pak, R.; Reed, C.; Richardson, E.; Roland, C.; Roland, G.; Sagerer, J.; Seals, H.; Sedykh, I.; Smith, C. E.; Stankiewicz, M. A.; Steinberg, P.; Stephans, G. S. F.; Sukhanov, A.; Szostak, A.; Tonjes, M. B.; Trzupek, A.; Vale, C.; Vannieuwenhuizen, G. J.; Vaurynovich, S. S.; Verdier, R.; Veres, G. I.; Walters, P.; Wenger, E.; Willhelm, D.; Wolfs, F. L. H.; Wosiek, B.; Wozniak, K.; Wyngaardt, S.; Wyslouch, B.

    The PHOBOS collaboration has carried out a systematic study of charged particle multiplicities in Cu+Cu and Au+Au collisions at the Relativistic Heavy-Ion Collider (RHIC) at Brookhaven National Laboratory. A unique feature of the PHOBOS detector is its ability to measure charged particles over a very wide angular range from 0.5° to 179.5° corresponding to |η| <5.4. The general features of the charged particle multiplicity distributions as a function of pseudo-rapidity, collision energy and centrality, as well as system size, are discussed.

  10. Three-Dimensional Cell Behavior in Microgels

    Science.gov (United States)

    Bhattacharjee, Tapomoy; Palmer, Glyn; Ghivizzani, Steven; Keselowsky, Benjamin; Sawyer, W. Gregory; Angelini, Thomas

    The number of dimensions in which particles can freely move strongly influences the collective behavior that emerges from their individual fluctuations. Thus, in 2D systems of cells in petri-dishes, our growing understanding of collective migration may be insufficient to explain cell behavior in 3D tissues. To study cell behavior in 3D, polymer scaffolds are used. Contemporary designs of 3D cell growth scaffolds enable cell migration and proliferative expansion by incorporating of degradable motifs. Matrix degradation creates space for cells to move and proliferate. However, different cell types and experimental conditions require the design of different scaffolds to optimize degradation with specific cell behaviors. By contrast, liquid like solids made from packed microgels can yield under cell generated stresses, allowing for cell motion without the need for scaffold degradation. Moreover, the use of microgels as 3D culture media allows arranging cells in arbitrary structures, harvesting cells, and delivering drugs and nutrients. Preliminary data describing cell behavior in 3D microgel culture will be presented. This material is based on work supported by the National Science Foundation under Grant No. DMR-1352043.

  11. Coordinates in relativistic Hamiltonian mechanics

    International Nuclear Information System (INIS)

    Sokolov, S.N.

    1984-01-01

    The physical (covariant and measurable) coordinates of free particles and covariant coordinates of the center of inertia are found for three main forms of relativistic dynamics. In the point form of dynamics, the covariant coordinates of two directly interacting particles are found, and the equations of motion are brought to the explicitly covariant form. These equations are generalized to the case of interaction with an external electromagnetic field

  12. Flukacad/Pipsicad: three-dimensional interfaces between Fluka and Autocad

    International Nuclear Information System (INIS)

    Helmut Vincke

    2001-01-01

    FLUKA is a widely used 3-D particle transport program. Up to now there was no possibility to display the simulation geometry or the calculated tracks in three dimensions. Even with FLUKA there exists only an option to picture two-dimensional views through the geometry used. This paper covers the description of two interface programs between the particle transport code FLUKA and the CAD program AutoCAD. These programs provide a three-dimensional facility not only for illustrating the simulated FLUKA geometry (FLUKACAD), but also for picturing simulated particle tracks (PIPSICAD) in a three-dimensional set-up. Additionally, the programming strategy for connecting FLUKA with AutoCAD is shown. A number of useful features of the programs themselves, but also of AutoCAD in the context of FLUKACAD and PIPSICAD, are explained. (authors)

  13. Dielectric spectroscopy for non-invasive monitoring of epithelial cell differentiation within three-dimensional scaffolds

    International Nuclear Information System (INIS)

    Daoud, Jamal; Tabrizian, Maryam; Asami, Koji; Rosenberg, Lawrence

    2012-01-01

    In this study, we introduce a cellular differentiation cellular model based on dielectric spectroscopy that characterizes epithelial differentiation processes. Non-invasive cellular monitoring was achieved within a three-dimensional microenvironment consisting of a cell-containing collagen I gel seeded onto microfabricated scaffolds. In this proof-of-concept investigation, Madin–Darby canine kidney cells were cultured within microfabricated, geometrically controlled scaffolds and allowed us to differentiate to hollow cyst-like structures. This transformation within the three-dimensional environment is monitored and characterized through dielectric spectroscopy while maintaining cell culture in vitro. (paper)

  14. One-dimensional integral equations for a system of three identical particles in the boundary condition models and the possibility of changing the off-shell behaviour of the two-particle t-matrix

    International Nuclear Information System (INIS)

    Efimov, V.N.; Schulz, H.

    1976-01-01

    It is shown that in the framework of the boundary condition models (BCM) for the two-particle interaction the Schroedinger equation for the system of three identical bosons can be reduced to the one-dimensional integral equation in an exact way. The method used for obtaining such an equation is based on a special consideration of the two-particle off-shell wave functions. The binding energy of the simple three-particle system is calculated. It is indicated that by means of the equation obtained it is possible to change the off-shell behaviour of the two-particle t-matrix and therefore to simulate three particle effects. (Auth.)

  15. Efimov effect, Thomas effect and model dependence of three-particle observables

    International Nuclear Information System (INIS)

    Adhikari, S.K.; Delfino, A.; Frederico, T.; Goldman, I.D.; Tomio, L.

    1987-01-01

    It is demonstrated for the three-dimensional three-particle system that a divergence arising from essentially the same singularity structure of the Kernel of the scattering integral equation is responsible for both the Efimov and Thomas effects. The above divergence implies that the results of three-particle dynamical calculation be sensitive to the details of the two-particle interaction. In two-dimensional systems the above divergence is absent and consequently the three-particle observables become essentially model independent. (M.W.O.) [pt

  16. Three-dimensional simulation of the motion of a single particle under a simulated turbulent velocity field

    Science.gov (United States)

    Moreno-Casas, P. A.; Bombardelli, F. A.

    2015-12-01

    A 3D Lagrangian particle tracking model is coupled to a 3D channel velocity field to simulate the saltation motion of a single sediment particle moving in saltation mode. The turbulent field is a high-resolution three dimensional velocity field that reproduces a by-pass transition to turbulence on a flat plate due to free-stream turbulence passing above de plate. In order to reduce computational costs, a decoupled approached is used, i.e., the turbulent flow is simulated independently from the tracking model, and then used to feed the 3D Lagrangian particle model. The simulations are carried using the point-particle approach. The particle tracking model contains three sub-models, namely, particle free-flight, a post-collision velocity and bed representation sub-models. The free-flight sub-model considers the action of the following forces: submerged weight, non-linear drag, lift, virtual mass, Magnus and Basset forces. The model also includes the effect of particle angular velocity. The post-collision velocities are obtained by applying conservation of angular and linear momentum. The complete model was validated with experimental results from literature within the sand range. Results for particle velocity time series and distribution of particle turbulent intensities are presented.

  17. Dirac particle in a box, and relativistic quantum Zeno dynamics

    International Nuclear Information System (INIS)

    Menon, Govind; Belyi, Sergey

    2004-01-01

    After developing a complete set of eigenfunctions for a Dirac particle restricted to a box, the quantum Zeno dynamics of a relativistic system is considered. The evolution of a continuously observed quantum mechanical system is governed by the theorem put forth by Misra and Sudarshan. One of the conditions for quantum Zeno dynamics to be manifest is that the Hamiltonian is semi-bounded. This Letter analyzes the effects of continuous observation of a particle whose time evolution is generated by the Dirac Hamiltonian. The theorem by Misra and Sudarshan is not applicable here since the Dirac operator is not semi-bounded

  18. Dynamical symmetries of two-dimensional systems in relativistic quantum mechanics

    International Nuclear Information System (INIS)

    Zhang Fulin; Song Ci; Chen Jingling

    2009-01-01

    The two-dimensional Dirac Hamiltonian with equal scalar and vector potentials has been proved commuting with the deformed orbital angular momentum L. When the potential takes the Coulomb form, the system has an SO(3) symmetry, and similarly the harmonic oscillator potential possesses an SU(2) symmetry. The generators of the symmetric groups are derived for these two systems separately. The corresponding energy spectra are yielded naturally from the Casimir operators. Their non-relativistic limits are also discussed

  19. Kadomtsev-Petviashvili solitons propagation in a plasma system with superthermal and weakly relativistic effects

    International Nuclear Information System (INIS)

    Hafeez-Ur-Rehman; Mahmood, S.; Shah, Asif; Haque, Q.

    2011-01-01

    Two dimensional (2D) solitons are studied in a plasma system comprising of relativistically streaming ions, kappa distributed electrons, and positrons. Kadomtsev-Petviashvili (KP) equation is derived through the reductive perturbation technique. Analytical solution of the KP equation has been studied numerically and graphically. It is noticed that kappa parameters of electrons and positrons as well as the ions relativistic streaming factor have an emphatic influence on the structural as well as propagation characteristics of two dimensional solitons in the considered plasma system. Our results may be helpful in the understanding of soliton propagation in astrophysical and laboratory plasmas, specifically the interaction of pulsar relativistic wind with supernova ejecta and the transfer of energy to plasma by intense electric field of laser beams producing highly energetic superthermal and relativistic particles [L. Arons, Astrophys. Space Sci. Lib. 357, 373 (2009); P. Blasi and E. Amato, Astrophys. Space Sci. Proc. 2011, 623; and A. Shah and R. Saeed, Plasma Phys. Controlled Fusion 53, 095006 (2011)].

  20. Nonlinear dynamics of electromagnetic pulses in cold relativistic plasmas

    Energy Technology Data Exchange (ETDEWEB)

    Bonatto, A.; Pakter, R.; Rizzato, F.B. [Universidade Federal do Rio Grande do Sul, Instituto de Fisica, Rio Grande do Sul (Brazil)

    2004-07-01

    The propagation of intense electromagnetic pulses in plasmas is a subject of current interest particularly for particle acceleration and laser fusion.In the present analysis we study the self consistent propagation of nonlinear electromagnetic pulses in a one dimensional relativistic electron-ion plasma, from the perspective of nonlinear dynamics. We show how a series of Hamiltonian bifurcations give rise to the electric fields which are of relevance in the subject of particle acceleration. Connections between these bifurcated solutions and results of earlier analysis are made. (authors)

  1. Nonlinear dynamics of electromagnetic pulses in cold relativistic plasmas

    International Nuclear Information System (INIS)

    Bonatto, A.; Pakter, R.; Rizzato, F.B.

    2004-01-01

    The propagation of intense electromagnetic pulses in plasmas is a subject of current interest particularly for particle acceleration and laser fusion.In the present analysis we study the self consistent propagation of nonlinear electromagnetic pulses in a one dimensional relativistic electron-ion plasma, from the perspective of nonlinear dynamics. We show how a series of Hamiltonian bifurcations give rise to the electric fields which are of relevance in the subject of particle acceleration. Connections between these bifurcated solutions and results of earlier analysis are made. (authors)

  2. Mass, Momentum and Kinetic Energy of a Relativistic Particle

    Science.gov (United States)

    Zanchini, Enzo

    2010-01-01

    A rigorous definition of mass in special relativity, proposed in a recent paper, is recalled and employed to obtain simple and rigorous deductions of the expressions of momentum and kinetic energy for a relativistic particle. The whole logical framework appears as the natural extension of the classical one. Only the first, second and third laws of…

  3. THREEDANT: A code to perform three-dimensional, neutral particle transport calculations

    International Nuclear Information System (INIS)

    Alcouffe, R.E.

    1994-01-01

    The THREEDANT code solves the three-dimensional neutral particle transport equation in its first order, multigroup, discrate ordinate form. The code allows an unlimited number of groups (depending upon the cross section set), angular quadrature up to S-100, and unlimited Pn order again depending upon the cross section set. The code has three options for spatial differencing, diamond with set-to-zero fixup, adaptive weighted diamond, and linear modal. The geometry options are XYZ and RZΘ with a special XYZ option based upon a volume fraction method. This allows objects or bodies of any shape to be modelled as input which gives the code as much geometric description flexibility as the Monte Carlo code MCNP. The transport equation is solved by source iteration accelerated by the DSA method. Both inner and outer iterations are so accelerated. Some results are presented which demonstrate the effectiveness of these techniques. The code is available on several types of computing platforms

  4. Relativistic-particle quantum mechanics (applications and approximations) II

    International Nuclear Information System (INIS)

    Coester, F.

    1981-01-01

    In this lecture I hope to show that relativistic-particle quantum mechanics with direct interactions is a useful tool for building models applicable to hadron systems at intermediate energies. To do this I will first describe a class of models designed to incorporate nucleon-nucleon interactions, pion production, absorption and scattering into a single dynamical framework without dressing the nucleons with pion clouds. The second major topic concerns electromagnetic interactions. In the previous lecture I specifically excluded long-rang forces and zero-mass particles. Since many of the experimental data in hadron physics involve electromagnetic interactions this limitation is a major defect which must be addressed

  5. A search for relativistic particles with fractional electric charge at the Cern collider

    DEFF Research Database (Denmark)

    Banner, M.; Kofoed-Hansen, O.

    1983-01-01

    A search for relativistic particles with fractional electric charge has been performed at the CERN collider using a telescope of scintillation counters to detect particles with abnormally low ionisation. The thickness of the detector (40 gr cm−2) limits this search to particles without strong...

  6. Formation of hard power laws in the energetic particle spectra resulting from relativistic magnetic reconnection.

    Science.gov (United States)

    Guo, Fan; Li, Hui; Daughton, William; Liu, Yi-Hsin

    2014-10-10

    Using fully kinetic simulations, we demonstrate that magnetic reconnection in relativistic plasmas is highly efficient at accelerating particles through a first-order Fermi process resulting from the curvature drift of particles in the direction of the electric field induced by the relativistic flows. This mechanism gives rise to the formation of hard power-law spectra in parameter regimes where the energy density in the reconnecting field exceeds the rest mass energy density σ ≡ B(2)/(4πnm(e)c(2))>1 and when the system size is sufficiently large. In the limit σ ≫ 1, the spectral index approaches p = 1 and most of the available energy is converted into nonthermal particles. A simple analytic model is proposed which explains these key features and predicts a general condition under which hard power-law spectra will be generated from magnetic reconnection.

  7. Fundamentals of relativistic particle beam optics

    International Nuclear Information System (INIS)

    Cornacchia, M.

    1995-12-01

    This lecture introduces the nonaccelerator-specialist to the motion of charged particles in a Storage Ring. The topics of discussion are restricted to the linear and nonlinear dynamics of a single particle in the transverse plane, i.e., the plane perpendicular to the direction of motion. The major omissions for a complete review of accelerator theory, for which a considerable literature exists, are the energy and phase oscillations (1). Other important accelerator physics aspects not treated here are the collective instabilities (2), the role of synchrotron radiation in electron storage rings (3), scattering processes (4), and beam-beam effects in colliding beam facilities (5). Much of the discussion that follows applies equally well to relativistic electron, proton, or ion synchrotrons. In this narrative, we refer to the particle as electron. After a broad overview, the magnetic forces acting on the electrons and the associated differential equations of motion are discussed. Solutions of the equations are given without derivation; the method of solution is outlined. and references for deeper studies are given. In this paper, the word electron is used to signify electron or positron. The dynamics of a single particle are not affected by the sign of its charge when the magnetic field direction is changed accordingly

  8. THREE-DIMENSIONAL RELATIVISTIC MAGNETOHYDRODYNAMIC SIMULATIONS OF CURRENT-DRIVEN INSTABILITY. I. INSTABILITY OF A STATIC COLUMN

    International Nuclear Information System (INIS)

    Mizuno, Yosuke; Nishikawa, Ken-Ichi; Lyubarsky, Yuri; Hardee, Philip E.

    2009-01-01

    We have investigated the development of current-driven (CD) kink instability through three-dimensional relativistic magnetohydrodynamic simulations. A static force-free equilibrium helical magnetic configuration is considered in order to study the influence of the initial configuration on the linear and nonlinear evolution of the instability. We found that the initial configuration is strongly distorted but not disrupted by the kink instability. The instability develops as predicted by linear theory. In the nonlinear regime, the kink amplitude continues to increase up to the terminal simulation time, albeit at different rates, for all but one simulation. The growth rate and nonlinear evolution of the CD kink instability depend moderately on the density profile and strongly on the magnetic pitch profile. The growth rate of the kink mode is reduced in the linear regime by an increase in the magnetic pitch with radius and reaches the nonlinear regime at a later time than the case with constant helical pitch. On the other hand, the growth rate of the kink mode is increased in the linear regime by a decrease in the magnetic pitch with radius and reaches the nonlinear regime sooner than the case with constant magnetic pitch. Kink amplitude growth in the nonlinear regime for decreasing magnetic pitch leads to a slender helically twisted column wrapped by magnetic field. On the other hand, kink amplitude growth in the nonlinear regime nearly ceases for increasing magnetic pitch.

  9. Instability of the time splitting scheme for the one-dimensional and relativistic Vlasov-Maxwell system

    CERN Document Server

    Huot, F; Bertrand, P; Sonnendrücker, E; Coulaud, O

    2003-01-01

    The Time Splitting Scheme (TSS) has been examined within the context of the one-dimensional (1D) relativistic Vlasov-Maxwell model. In the strongly relativistic regime of the laser-plasma interaction, the TSS cannot be applied to solve the Vlasov equation. We propose a new semi-Lagrangian scheme based on a full 2D advection and study its advantages over the classical Splitting procedure. Details of the underlying integration of the Vlasov equation appear to be important in achieving accurate plasma simulations. Examples are given which are related to the relativistic modulational instability and the self-induced transparency of an ultra-intense electromagnetic pulse in the relativistic regime.

  10. Relativistic Equations for Spin Particles: What can We Learn from Noncommutativity?

    International Nuclear Information System (INIS)

    Dvoeglazov, V. V.

    2009-01-01

    We derive relativistic equations for charged and neutral spin particles. The approach for higher-spin particles is based on generalizations of the Bargmann-Wigner formalism. Next, we study, what new physical information can give the introduction of non-commutativity. Additional non-commutative parameters can provide a suitable basis for explanation of the origin of mass.

  11. Relativistic acceleration of captured particles by a longitudinal wave in a slightly inhomogeneous plasma

    International Nuclear Information System (INIS)

    Erokhin, N.S.; Zol'nikova, N.N.; Mikhajlovskaya, L.A.

    1991-01-01

    Relativistic acceleration of charged particles, captured by a longitudinal wave in a slightly inhomogeneous plasma without an external magnetic field is considered numerically and analytically. It is shown that with the growth of the plasma inhomogeneity parameter the maximum energy of accelerated captured particles exponentially increases. Attention is paid to the possibility of 'eternal' confinement and, respectively, unlimited acceleration of captured particles by an undamped longitudinal wave in a plasma without a magnetic field

  12. Random-subset fitting of digital holograms for fast three-dimensional particle tracking [invited].

    Science.gov (United States)

    Dimiduk, Thomas G; Perry, Rebecca W; Fung, Jerome; Manoharan, Vinothan N

    2014-09-20

    Fitting scattering solutions to time series of digital holograms is a precise way to measure three-dimensional dynamics of microscale objects such as colloidal particles. However, this inverse-problem approach is computationally expensive. We show that the computational time can be reduced by an order of magnitude or more by fitting to a random subset of the pixels in a hologram. We demonstrate our algorithm on experimentally measured holograms of micrometer-scale colloidal particles, and we show that 20-fold increases in speed, relative to fitting full frames, can be attained while introducing errors in the particle positions of 10 nm or less. The method is straightforward to implement and works for any scattering model. It also enables a parallelization strategy wherein random-subset fitting is used to quickly determine initial guesses that are subsequently used to fit full frames in parallel. This approach may prove particularly useful for studying rare events, such as nucleation, that can only be captured with high frame rates over long times.

  13. Coherent oscillations of a ring of relativistic particles

    International Nuclear Information System (INIS)

    Hofmann, I.

    1976-07-01

    The effect of ring curvature on the coherent perturbations of a ring of relativistic particles is studied within the framework of the linearized Vlasov equation. Finite curvature is shown to have a minor effect on the dynamics of the 'negative mass' mode; the 'transverse' mode in radial direction, however, is found to be coupled with a simultaneous longitudinal density modulation which modifies the dispersion relation. In the limit of small mode frequency (ω/Ω [de

  14. On the injection of relativistic particles into the Crab Nebula

    International Nuclear Information System (INIS)

    Shklovskij, I.S.

    1977-01-01

    It is shown that a flux of relativistic electrons from the NP 0532 pulsar magnetosphere, responsible for its synchrotron emission, cannot provide the necessary energy pumping to the Crab Nebula. A conclusion is reached that such a pumping can be effectuated by a flow of relativistic electrons leaving the NP 0532 magnetosphere at small pitch angles and giving therefore no appreciable contribution to the synchrotron emission of the pulsar. An interpretation of the Crab Nebula synchrotron spectrum is given on the assumption of secular ''softening'' of the energy spectrum of the relativistic electrons injected into the Nebula. A possibility of explanation of the observed rapid variability of some features in the central part of the Nebula by ejection of free - neutron - rich dense gas clouds from the pulsar surface during ''starquakes'' is discussed. The clouds of rather dense (nsub(e) approximately 10 7 cm -3 ) plasma, thus formed at about 10 13 cm from pulsar, will be accelerated up to relativistic velocities by the pressure of the magneto-dipole radiation of NP 0532 and will deform the magnetic field in the inner part (R 17 cm) of the Crab Nebula, that is the cause of the variability observed. In this case, favourable conditions for the acceleration of the particles in the cloud up to relativistic energies are realized; that may be an additional source of injection

  15. RECONSTRUCTING THREE-DIMENSIONAL JET GEOMETRY FROM TWO-DIMENSIONAL IMAGES

    Science.gov (United States)

    Avachat, Sayali; Perlman, Eric S.; Li, Kunyang; Kosak, Katie

    2018-01-01

    Relativistic jets in AGN are one of the most interesting and complex structures in the Universe. Some of the jets can be spread over hundreds of kilo parsecs from the central engine and display various bends, knots and hotspots. Observations of the jets can prove helpful in understanding the emission and particle acceleration processes from sub-arcsec to kilo parsec scales and the role of magnetic field in it. The M87 jet has many bright knots as well as regions of small and large bends. We attempt to model the jet geometry using the observed 2 dimensional structure. The radio and optical images of the jet show evidence of presence of helical magnetic field throughout. Using the observed structure in the sky frame, our goal is to gain an insight into the intrinsic 3 dimensional geometry in the jets frame. The structure of the bends in jet's frame may be quite different than what we see in the sky frame. The knowledge of the intrinsic structure will be helpful in understanding the appearance of the magnetic field and hence polarization morphology. To achieve this, we are using numerical methods to solve the non-linear equations based on the jet geometry. We are using the Log Likelihood method and algorithm based on Markov Chain Monte Carlo (MCMC) simulations.

  16. The (2+1)-dimensional nonisospectral relativistic Toda hierarchy related to the generalized discrete Painleve hierarchy

    International Nuclear Information System (INIS)

    Zhu Zuonong

    2007-01-01

    In this paper, we will concentrate on the topic of integrable discrete hierarchies in 2+1 dimensions, and their connection with discrete Painleve hierarchies. By considering a (2+1)-dimensional nonisospectral discrete linear problem, two new (2+1)-dimensional nonisospectral integrable lattice hierarchies-the 2+1 nonisospectral relativistic Toda lattice hierarchy and the 2+1 nonisospectral negative relativistic Toda lattice hierarchy-are constructed. It is shown that the reductions of the two new 2+1 nonisospectral lattice hierarchies lead to the (2+1)-dimensional nonisospectral Volterra lattice hierarchy and the (2+1)-dimensional nonisospectral negative Volterra lattice hierarchy. We also obtain two new (1+1)-dimensional nonisospectral integrable lattice hierarchies and two new ordinary difference hierarchies which are direct reductions of the two 2+1 nonisospectral integrable lattice hierarchies. One of the two difference hierarchies yields our previously obtained generalized discrete first Painleve (dP I ) hierarchy and another one yields a generalized alternative discrete second Painleve (alt-dP II ) hierarchy

  17. Random phase approximation in relativistic approach

    International Nuclear Information System (INIS)

    Ma Zhongyu; Yang Ding; Tian Yuan; Cao Ligang

    2009-01-01

    Some special issues of the random phase approximation(RPA) in the relativistic approach are reviewed. A full consistency and proper treatment of coupling to the continuum are responsible for the successful application of the RPA in the description of dynamical properties of finite nuclei. The fully consistent relativistic RPA(RRPA) requires that the relativistic mean filed (RMF) wave function of the nucleus and the RRPA correlations are calculated in a same effective Lagrangian and the consistent treatment of the Dirac sea of negative energy states. The proper treatment of the single particle continuum with scattering asymptotic conditions in the RMF and RRPA is discussed. The full continuum spectrum can be described by the single particle Green's function and the relativistic continuum RPA is established. A separable form of the paring force is introduced in the relativistic quasi-particle RPA. (authors)

  18. Physically-induced cytoskeleton remodeling of cells in three-dimensional culture.

    Directory of Open Access Journals (Sweden)

    Sheng-Lin Lee

    Full Text Available Characterizing how cells in three-dimensional (3D environments or natural tissues respond to biophysical stimuli is a longstanding challenge in biology and tissue engineering. We demonstrate a strategy to monitor morphological and mechanical responses of contractile fibroblasts in a 3D environment. Cells responded to stretch through specific, cell-wide mechanisms involving staged retraction and reinforcement. Retraction responses occurred for all orientations of stress fibers and cellular protrusions relative to the stretch direction, while reinforcement responses, including extension of cellular processes and stress fiber formation, occurred predominantly in the stretch direction. A previously unreported role of F-actin clumps was observed, with clumps possibly acting as F-actin reservoirs for retraction and reinforcement responses during stretch. Responses were consistent with a model of cellular sensitivity to local physical cues. These findings suggest mechanisms for global actin cytoskeleton remodeling in non-muscle cells and provide insight into cellular responses important in pathologies such as fibrosis and hypertension.

  19. Coherent quantum states of a relativistic particle in an electromagnetic plane wave and a parallel magnetic field

    International Nuclear Information System (INIS)

    Colavita, E.; Hacyan, S.

    2014-01-01

    We analyze the solutions of the Klein–Gordon and Dirac equations describing a charged particle in an electromagnetic plane wave combined with a magnetic field parallel to the direction of propagation of the wave. It is shown that the Klein–Gordon equation admits coherent states as solutions, while the corresponding solutions of the Dirac equation are superpositions of coherent and displaced-number states. Particular attention is paid to the resonant case in which the motion of the particle is unbounded. -- Highlights: •We study a relativistic electron in a particular electromagnetic field configuration. •New exact solutions of the Klein–Gordon and Dirac equations are obtained. •Coherent and displaced number states can describe a relativistic particle

  20. Particle-in-cell plasma simulation codes on the connection machine

    International Nuclear Information System (INIS)

    Walker, D.W.

    1991-01-01

    Methods for implementing three-dimensional, electromagnetic, relativistic PIC plasma simulation codes on the Connection Machine (CM-2) are discussed. The gather and scatter phases of the PIC algorithm involve indirect indexing of data, which results in a large amount of communication on the CM-2. Different data decompositions are described that seek to reduce the amount of communication while maintaining good load balance. These methods require the particles to be spatially sorted at the start of each time step, which introduced another form of overhead. The different methods are implemented in CM Fortran on the CM-2 and compared. It was found that the general router is slow in performing the communication in the gather and scatter steps, which precludes an efficient CM Fortran implementation. An alternative method that uses PARIS calls and the NEWS communication network to pipeline data along the axes of the VP set is suggested as a more efficient algorithm

  1. Investigating the Role of Surface Materials and Three Dimensional Architecture on In Vitro Differentiation of Porcine Monocyte-Derived Dendritic Cells.

    Science.gov (United States)

    Hartmann, Sofie Bruun; Mohanty, Soumyaranjan; Skovgaard, Kerstin; Brogaard, Louise; Flagstad, Frederikke Bjergvang; Emnéus, Jenny; Wolff, Anders; Summerfield, Artur; Jungersen, Gregers

    2016-01-01

    In vitro generation of dendritic-like cells through differentiation of peripheral blood monocytes is typically done using two-dimensional polystyrene culture plates. In the process of optimising cell culture techniques, engineers have developed fluidic micro-devises usually manufactured in materials other than polystyrene and applying three-dimensional structures more similar to the in vivo environment. Polydimethylsiloxane (PDMS) is an often used polymer for lab-on-a-chip devices but not much is known about the effect of changing the culture surface material from polystyrene to PDMS. In the present study the differentiation of porcine monocytes to monocyte-derived dendritic cells (moDCs) was investigated using CD172apos pig blood monocytes stimulated with GM-CSF and IL-4. Monocytes were cultured on surfaces made of two- and three-dimensional polystyrene as well as two- and three-dimensional PDMS and carbonised three-dimensional PDMS. Cells cultured conventionally (on two-dimensional polystyrene) differentiated into moDCs as expected. Interestingly, gene expression of a wide range of cytokines, chemokines, and pattern recognition receptors was influenced by culture surface material and architecture. Distinct clustering of cells, based on similar expression patterns of 46 genes of interest, was seen for cells isolated from two- and three-dimensional polystyrene as well as two- and three-dimensional PDMS. Changing the material from polystyrene to PDMS resulted in cells with expression patterns usually associated with macrophage expression (upregulation of CD163 and downregulation of CD1a, FLT3, LAMP3 and BATF3). However, this was purely based on gene expression level, and no functional assays were included in this study which would be necessary in order to classify the cells as being macrophages. When changing to three-dimensional culture the cells became increasingly activated in terms of IL6, IL8, IL10 and CCR5 gene expression. Further stimulation with LPS resulted

  2. Investigating the Role of Surface Materials and Three Dimensional Architecture on In Vitro Differentiation of Porcine Monocyte-Derived Dendritic Cells.

    Directory of Open Access Journals (Sweden)

    Sofie Bruun Hartmann

    Full Text Available In vitro generation of dendritic-like cells through differentiation of peripheral blood monocytes is typically done using two-dimensional polystyrene culture plates. In the process of optimising cell culture techniques, engineers have developed fluidic micro-devises usually manufactured in materials other than polystyrene and applying three-dimensional structures more similar to the in vivo environment. Polydimethylsiloxane (PDMS is an often used polymer for lab-on-a-chip devices but not much is known about the effect of changing the culture surface material from polystyrene to PDMS. In the present study the differentiation of porcine monocytes to monocyte-derived dendritic cells (moDCs was investigated using CD172apos pig blood monocytes stimulated with GM-CSF and IL-4. Monocytes were cultured on surfaces made of two- and three-dimensional polystyrene as well as two- and three-dimensional PDMS and carbonised three-dimensional PDMS. Cells cultured conventionally (on two-dimensional polystyrene differentiated into moDCs as expected. Interestingly, gene expression of a wide range of cytokines, chemokines, and pattern recognition receptors was influenced by culture surface material and architecture. Distinct clustering of cells, based on similar expression patterns of 46 genes of interest, was seen for cells isolated from two- and three-dimensional polystyrene as well as two- and three-dimensional PDMS. Changing the material from polystyrene to PDMS resulted in cells with expression patterns usually associated with macrophage expression (upregulation of CD163 and downregulation of CD1a, FLT3, LAMP3 and BATF3. However, this was purely based on gene expression level, and no functional assays were included in this study which would be necessary in order to classify the cells as being macrophages. When changing to three-dimensional culture the cells became increasingly activated in terms of IL6, IL8, IL10 and CCR5 gene expression. Further stimulation

  3. Relativistic Quantum Transport in Graphene Systems

    Science.gov (United States)

    2015-07-09

    dimensional Dirac material systems. 2 List of Publications 1. X. Ni, L. Huang, Y.-C. Lai, and L. M. Pecora, “Effect of chaos on relativistic quantum...development of relativistic quantum devices based on graphene or alternative two-dimensional Dirac material systems. In the project period, we studied

  4. Particle coagulation in molten metal based on three-dimensional analysis of cluster by x-ray micro-computer tomography (CT)

    International Nuclear Information System (INIS)

    Li, Tao; Shimasaki, Shin-ichi; Taniguchi, Shoji; Narita, Shunsuke; Uesugi, Kentaro

    2013-01-01

    Particle coagulation plays a key role in steel refining process to remove inclusions. Many research works focus on the behaviors of particle coagulation. To reveal its mechanism water model experiments have been performed by some researchers including the authors' group. In this paper, experiments of particle coagulation were carried out with molten Al including SiC particles in a mechanically agitated crucible with two baffles. Particle coagulation and formation of clusters were observed on the microscopy images of as-polished samples. Three-dimensional (3D) analysis of the clusters in solidified Al was implemented by X-ray micro CT available at SPring-8. The methods to distinguish clusters on two-dimensional (2D) cross-sectional images were discussed, which were established in the previous works by the present authors' group. The characteristics of the 3D SiC clusters and their 2D cross-sections were analyzed. The statistical ranges of the parameters for 2D clusters were used as criterions to distinguish the clusters on 2D microscopy images from the as-polished samples. The kinetics of SiC particle coagulation was studied by the measured cluster number density and size using our program to distinguish cluster in 2D cross-sectional images according to 3D information (DC-2D-3D). The calculated and experimental results of the SiC particle coagulation in molten Al agree well with each other. (author)

  5. Cooling and focusing of a relativistic charged particle beam in crossed laser field

    International Nuclear Information System (INIS)

    Li Fuli

    1987-01-01

    A new method to focus a relativistic charged particle beam is suggested and studied. This idea is based on the use of the ponderomotive force which arises when a periodic electromagnetic field is created, as in the case of two crossed laser beams. (author)

  6. In vitro three-dimensional coculturing poly3-hydroxybutyrate-co-3-hydroxyhexanoate with mouse-induced pluripotent stem cells for myocardial patch application.

    Science.gov (United States)

    Shijun, Xu; Junsheng, Mu; Jianqun, Zhang; Ping, Bo

    2016-03-01

    Identifying a suitable polymeric biomaterial for myocardial patch repair following myocardial infarction, cerebral infarction, and cartilage injury is essential. This study aimed to investigate the effect of the novel polymer material, poly3-hydroxybutyrate-co-3-hydroxyhexanoate, on the adhesion, proliferation, and differentiation of mouse-induced pluripotent stem cells in vitro. Mouse-induced pluripotent stem cells were isolated, expanded, and cultured on either two-dimensional or three-dimensional poly3-hydroxybutyrate-co-3-hydroxyhexanoate films (membranes were perforated to imitate three-dimensional space). Following attachment onto the films, mouse-induced pluripotent stem cell morphology was visualized using scanning electron microscopy. Cell vitality was detected using the Cell Counting Kit-8 assay and cell proliferation was observed using fluorescent 4',6-diamidino-2-phenylindole (DAPI) staining. Mouse-induced pluripotent stem cells were induced into cardiomyocytes by differentiation medium containing vitamin C. A control group in the absence of an inducer was included. Mouse-induced pluripotent stem cell survival and differentiation were observed using immunofluorescence and flow cytometry, respectively. Mouse-induced pluripotent stem cells growth, proliferation, and differentiation were observed on both two-dimensional and three-dimensional poly3-hydroxybutyrate-co-3-hydroxyhexanoate films. Vitamin C markedly improved the efficiency of mouse-induced pluripotent stem cells differentiation into cardiomyocytes on poly3-hydroxybutyrate-co-3-hydroxyhexanoate films. Three-dimensional culture was better at promoting mouse-induced pluripotent stem cell proliferation and differentiation compared with two-dimensional culture. © The Author(s) 2016.

  7. Relativistic scattering theory of two charged spinless particles

    International Nuclear Information System (INIS)

    Alt, E.O.; Hannemann

    1985-01-01

    In the framework of a relativistic quantum mechanics, the authors calculate for two spinless particles with Coulomb interaction exactly the partial-wave S-matrix and the full scattering amplitude. From the former they can extract the exact binding energies which, when expanded in powers of α, reproduce in the hydrogenic case the fourth-order result of a previous study. In the weak field limit, the latter coincides with the amplitude derived by another study from QED in eikonal approximation

  8. Dynamic bremsstrahlung from relativistic particles scattered by atom

    International Nuclear Information System (INIS)

    Astapenko, V.A.; Bujmistrov, V.M.; Krotov, Yu.A.; Mikhajlov, L.K.; Trakhtenberg, L.I.

    1985-01-01

    The bremsstrahlung cross section for a relativistic particle scattered by an atom is calculated. In contrast to the screening approximation usually employed, the influence of the atomic electron on the bremsstrahlung is taken into account exactly, viz., the atomic electron is considered as a moving particle interacting with the electromagnetic field and not only as the source of a static external field. Consequently, along with the static term which leads to the Bethe-Heitw,ler formula, a ne dynamic, term appears in the transition amplitude. The corresponding cross section, the dynamic bremsstrahlung cross section, in certain frequensy ranges and certain ranges of the directions of photon emission exceeds considerably the static bremsstrahlung cross section

  9. Multiwavelength Observations of Relativistic Jets from General Relativistic Magnetohydrodynamic Simulations

    Directory of Open Access Journals (Sweden)

    Richard Anantua

    2018-03-01

    Full Text Available This work summarizes a program intended to unify three burgeoning branches of the high-energy astrophysics of relativistic jets: general relativistic magnetohydrodynamic (GRMHD simulations of ever-increasing dynamical range, the microphysical theory of particle acceleration under relativistic conditions, and multiwavelength observations resolving ever-decreasing spatiotemporal scales. The process, which involves converting simulation output into time series of images and polarization maps that can be directly compared to observations, is performed by (1 self-consistently prescribing models for emission, absorption, and particle acceleration and (2 performing time-dependent polarized radiative transfer. M87 serves as an exemplary prototype for this investigation due to its prominent and well-studied jet and the imminent prospect of learning much more from Event Horizon Telescope (EHT observations this year. Synthetic observations can be directly compared with real observations for observational signatures such as jet instabilities, collimation, relativistic beaming, and polarization. The simplest models described adopt the standard equipartition hypothesis; other models calculate emission by relating it to current density or shear. These models are intended for application to the radio jet instead of the higher frequency emission, the disk and the wind, which will be subjects of future investigations.

  10. Turbulence in Three Dimensional Simulations of Magnetopause Reconnection

    Science.gov (United States)

    Drake, J. F.; Price, L.; Swisdak, M.; Burch, J. L.; Cassak, P.; Dahlin, J. T.; Ergun, R.

    2017-12-01

    We present two- and three-dimensional particle-in-cell simulations of the 16 October 2015 MMS magnetopause reconnection event. While the two-dimensional simulation is laminar, turbulence develops at both the x-line and along the magnetic separatrices in the three-dimensional simulation. This turbulence is electromagnetic in nature, is characterized by a wavevector k given by kρ e ˜(m_e/m_i)0.25 with ρ e the electron Larmor radius, and appears to have the ion pressure gradient as its source of free energy. Taken together, these results suggest the instability is a variant of the lower-hybrid drift instability. The turbulence produces electric field fluctuations in the out-of-plane direction (the direction of the reconnection electric field) with an amplitude of around ± 10 mV/m, which is much greater than the reconnection electric field of around 0.1 mV/m. Such large values of the out-of-plane electric field have been identified in the MMS data. The turbulence in the simulation controls the scale lengths of the density profile and current layers in asymmetric reconnection, driving them closer to √ {ρ eρ_i } than the ρ e or de scalings seen in 2D reconnection simulations, where de is the electron inertial length. The turbulence is strong enough to make the magnetic field around the reconnection island chaotic and produces both anomalous resistivity and anomalous viscosity. Each contribute significantly to breaking the frozen-in condition in the electron diffusion region. The crescent-shaped features in velocity space seen both in MMS observations and in two-dimensional simulations survive, even in the turbulent environment of the three-dimensional system. We compare and contrast these results to a three-dimensional simulation of the 8 December 2015 MMS magnetopause reconnection event in which the reconnecting and out-of-plane guide fields are comparable. LHDI is still present in this event, although its appearance is modified by the presence of the guide

  11. Relativistic Wigner functions

    Directory of Open Access Journals (Sweden)

    Bialynicki-Birula Iwo

    2014-01-01

    Full Text Available Original definition of the Wigner function can be extended in a natural manner to relativistic domain in the framework of quantum field theory. Three such generalizations are described. They cover the cases of the Dirac particles, the photon, and the full electromagnetic field.

  12. The Wigner function in the relativistic quantum mechanics

    Energy Technology Data Exchange (ETDEWEB)

    Kowalski, K., E-mail: kowalski@uni.lodz.pl; Rembieliński, J.

    2016-12-15

    A detailed study is presented of the relativistic Wigner function for a quantum spinless particle evolving in time according to the Salpeter equation. - Highlights: • We study the Wigner function for a quantum spinless relativistic particle. • We discuss the relativistic Wigner function introduced by Zavialov and Malokostov. • We introduce relativistic Wigner function based on the standard definition. • We find analytic expressions for relativistic Wigner functions.

  13. A mathematical model of collective cell migration in a three-dimensional, heterogeneous environment.

    Science.gov (United States)

    Stonko, David P; Manning, Lathiena; Starz-Gaiano, Michelle; Peercy, Bradford E

    2015-01-01

    Cell migration is essential in animal development, homeostasis, and disease progression, but many questions remain unanswered about how this process is controlled. While many kinds of individual cell movements have been characterized, less effort has been directed towards understanding how clusters of cells migrate collectively through heterogeneous, cellular environments. To explore this, we have focused on the migration of the border cells during Drosophila egg development. In this case, a cluster of different cell types coalesce and traverse as a group between large cells, called nurse cells, in the center of the egg chamber. We have developed a new model for this collective cell migration based on the forces of adhesion, repulsion, migration and stochastic fluctuation to generate the movement of discrete cells. We implement the model using Identical Math Cells, or IMCs. IMCs can each represent one biological cell of the system, or can be aggregated using increased adhesion forces to model the dynamics of larger biological cells. The domain of interest is filled with IMCs, each assigned specific biophysical properties to mimic a diversity of cell types. Using this system, we have successfully simulated the migration of the border cell cluster through an environment filled with larger cells, which represent nurse cells. Interestingly, our simulations suggest that the forces utilized in this model are sufficient to produce behaviors of the cluster that are observed in vivo, such as rotation. Our framework was developed to capture a heterogeneous cell population, and our implementation strategy allows for diverse, but precise, initial position specification over a three- dimensional domain. Therefore, we believe that this model will be useful for not only examining aspects of Drosophila oogenesis, but also for modeling other two or three-dimensional systems that have multiple cell types and where investigating the forces between cells is of interest.

  14. A mathematical model of collective cell migration in a three-dimensional, heterogeneous environment.

    Directory of Open Access Journals (Sweden)

    David P Stonko

    Full Text Available Cell migration is essential in animal development, homeostasis, and disease progression, but many questions remain unanswered about how this process is controlled. While many kinds of individual cell movements have been characterized, less effort has been directed towards understanding how clusters of cells migrate collectively through heterogeneous, cellular environments. To explore this, we have focused on the migration of the border cells during Drosophila egg development. In this case, a cluster of different cell types coalesce and traverse as a group between large cells, called nurse cells, in the center of the egg chamber. We have developed a new model for this collective cell migration based on the forces of adhesion, repulsion, migration and stochastic fluctuation to generate the movement of discrete cells. We implement the model using Identical Math Cells, or IMCs. IMCs can each represent one biological cell of the system, or can be aggregated using increased adhesion forces to model the dynamics of larger biological cells. The domain of interest is filled with IMCs, each assigned specific biophysical properties to mimic a diversity of cell types. Using this system, we have successfully simulated the migration of the border cell cluster through an environment filled with larger cells, which represent nurse cells. Interestingly, our simulations suggest that the forces utilized in this model are sufficient to produce behaviors of the cluster that are observed in vivo, such as rotation. Our framework was developed to capture a heterogeneous cell population, and our implementation strategy allows for diverse, but precise, initial position specification over a three- dimensional domain. Therefore, we believe that this model will be useful for not only examining aspects of Drosophila oogenesis, but also for modeling other two or three-dimensional systems that have multiple cell types and where investigating the forces between cells is of

  15. Classical relativistic spinning particle with anomalous magnetic moment: The precession of spin

    International Nuclear Information System (INIS)

    Barut, A.O.; Cruz, M.G.

    1993-05-01

    The theory of classical relativistic spinning particles with c-number internal spinor variables, modelling accurately the Dirac electron, is generalized to particles with anomalous magnetic moments. The equations of motion are derived and the problem of spin precession is discussed and compared with other theories of spin. (author). 32 refs

  16. Particle Acceleration, Magnetic Field Generation and Associated Emission in Collisionless Relativistic Jets

    Science.gov (United States)

    Nishikawa, K. I.; Ramirez-Ruiz, E.; Hardee, P.; Mizuno, Y.; Fishman. G. J.

    2007-01-01

    Nonthermal radiation observed from astrophysical systems containing relativistic jets and shocks, e.g., active galactic nuclei (AGNs), gamma-ray bursts (GRBs), and Galactic microquasar systems usually have power-law emission spectra. Recent PIC simulations using injected relativistic electron-ion (electro-positron) jets show that acceleration occurs within the downstream jet. Shock acceleration is a ubiquitous phenomenon in astrophysical plasmas. Plasma waves and their associated instabilities (e.g., the Buneman instability, other two-streaming instability, and the Weibel instability) created in the shocks are responsible for particle (electron, positron, and ion) acceleration. The simulation results show that the Weibel instability is responsible for generating and amplifying highly nonuniform, small-scale magnetic fields. These magnetic fields contribute to the electron's transverse deflection behind the jet head. The "jitter" radiation from deflected electrons has different properties than synchrotron radiation which is calculated in a uniform magnetic field. This jitter radiation may be important to understanding the complex time evolution and/or spectral structure in gamma-ray bursts, relativistic jets, and supernova remnants.

  17. Recent progresses in relativistic beam-plasma instability theory

    Directory of Open Access Journals (Sweden)

    A. Bret

    2010-11-01

    Full Text Available Beam-plasma instabilities are a key physical process in many astrophysical phenomena. Within the fireball model of Gamma ray bursts, they first mediate a relativistic collisionless shock before they produce upstream the turbulence needed for the Fermi acceleration process. While non-relativistic systems are usually governed by flow-aligned unstable modes, relativistic ones are likely to be dominated by normally or even obliquely propagating waves. After reviewing the basis of the theory, results related to the relativistic kinetic regime of the poorly-known oblique unstable modes will be presented. Relevant systems besides the well-known electron beam-plasma interaction are presented, and it is shown how the concept of modes hierarchy yields a criterion to assess the proton to electron mass ratio in Particle in cell simulations.

  18. Numerical Simulation of the Motion of Aerosol Particles in Open Cell Foam Materials

    Science.gov (United States)

    Solovev, S. A.; Soloveva, O. V.; Popkova, O. S.

    2018-03-01

    The motion of aerosol particles in open cell foam material is studied. The porous medium is investigated for a three-dimensional case with detailed simulation of cellular structures within an ordered geometry. Numerical calculations of the motion of particles and their deposition due to inertial and gravitational mechanisms are performed. Deposition efficiency curves for a broad range of particle sizes are constructed. The effect deposition mechanisms have on the efficiency of the porous material as a filter is analyzed.

  19. Ho:YAG laser: intervertebral disk cell interaction using three-dimensional cell culture system

    Science.gov (United States)

    Sato, Masato; Ishihara, Miya; Arai, Tsunenori; Asazuma, Takashi; Kikuchi, Toshiyuki; Kikuchi, Makoto; Fujikawa, Kyosuke

    2000-06-01

    The purpose of this study is to evaluate the influence on the intervertebral disc cells after laser irradiation using three- dimensional culture system and to clarify the optimum Ho:YAG laser irradiation condition on percutaneous laser disc decompression (PLDD) for lumbar disc herniation. Since the Ho:YAG laser ablation is characterized by water-vapor bubble dynamics, not only thermal effect but also acoustic effect on cell metabolism might occur in the intervertebral disc. We studied the disc cell reaction from the metabolic point of view to investigate photothermal and photoacoustic effects on three-dimensional cultured disc cell. Intervertebral discs were obtained from female 30 Japanese white rabbits weighing about 1 kg. A pulsed Ho:YAG laser (wavelength: 2.1 micrometer, pulse width: about 200 microseconds) was delivered through a 200 micrometer-core diameter single silica glass fiber. We used the Ho:YAG laser irradiation fluence ranging from 60 to approximately 800 J/cm2 at the fiber end. To investigate acoustic effect, the acoustic transducer constructed with polyvinylidene fluoride (PVdF) film and acoustic absorber was used to detect the stress wave. Thermocouple and thermography were used to investigate thermal effect. Concerning damage of plasma membrane and ability of matrix synthesis, thermal effect might mainly affect cell reaction in total energy of 54 J (closed to practically used condition), but in 27 J, acoustic effect might contribute to it. We found that total energy was key parameter among the optimum condition, so that temperature and/or stress wave may influence Ho:YAG laser-disc cell interactions.

  20. Three-dimensional self-branching anatase TiO_2 nanorods with the improved carrier collection for SrTiO_3-based perovskite solar cells

    International Nuclear Information System (INIS)

    Hu, Yajing; Wang, Chen; Tang, Ying; Huang, Lu; Fu, Jianxun; Shi, Weimin; Wang, Linjun; Yang, Weiguang

    2016-01-01

    The organic–inorganic perovskite solar cells based on ternary oxide SrTiO_3 shows a higher Voc, attributed to its slightly higher conduction band edge and better morphology of absorber material. However, its less efficient carrier collection and limited overall interfacial areas between the absorber material and the electron-transport layer (ETL), dramatically reducing the Jsc. Here, By adjusting the concentrations of the Ti(OBu)_4, we successfully prepared the three-dimensional (3D) self-branching anatase TiO_2 nanorod/SrTiO_3 nanocomposites, and slightly tuned the particle size of SrTiO_3. With the incorporation of the three-dimensional (3D) self-branching anatase TiO_2 nanorod, the Jsc of the device based on SrTiO_3 was highly boosted. The best performing solar cell we obtained exhibited a PCE of 9.99% with a Jsc of 19.48 mA/cm"2. The excellent performance could be ascribed to the improvement of charge carrier collection of SrTiO_3, better surface coverage and crystallinity of CH_3NH_3PbI_3, and enhanced light scattering ability caused by 3D self-branching anatase TiO_2 nanorods. - Highlights: • The three-dimensional (3D) self-branching anatase TiO_2 nanorod/SrTiO_3 nanocomposites were prepared. • The particle sizes of SrTiO_3 can be slightly tuned. • The best performing solar cell we obtained exhibited a PCE of 9.99% with the Jsc of 19.48 mA/cm"2.

  1. Three dimensional monocular human motion analysis in end-effector space

    DEFF Research Database (Denmark)

    Hauberg, Søren; Lapuyade, Jerome; Engell-Nørregård, Morten Pol

    2009-01-01

    In this paper, we present a novel approach to three dimensional human motion estimation from monocular video data. We employ a particle filter to perform the motion estimation. The novelty of the method lies in the choice of state space for the particle filter. Using a non-linear inverse kinemati...

  2. Radiation reaction for the classical relativistic spinning particle in scalar, tensor and linearized gravitational fields

    International Nuclear Information System (INIS)

    Barut, A.O.; Cruz, M.G.

    1992-08-01

    We use the method of analytic continuation of the equation of motion including the self-fields to evaluate the radiation reaction for a classical relativistic spinning point particle in interaction with scalar, tensor and linearized gravitational fields in flat spacetime. In the limit these equations reduce to those of spinless particles. We also show the renormalizability of these theories. (author). 10 refs

  3. Fast numerical method for solving the three-dimensional Stokes' equations in the presence of suspended particles

    International Nuclear Information System (INIS)

    Fogelson, A.L.; Peskin, C.S.

    1988-01-01

    A new fast numerical method for solving the three-dimensional Stokes' equations in the presence of suspended particles is presented. The fluid dynamics equations are solved on a lattice. A particle is represented by a set of points each of which moves at the local fluid velocity and is not constrained to lie on the lattice. These points are coupled by forces which resist deformation of the particle. These forces contribute to the force density in the Stokes' equations. As a result, a single set of fluid dynamics equations holds at all points of the domain and there are no internal boundaries. Particles size, shape, and deformability may be prescribed. Computational work increases only linearly with the number of particles, so large numbers (500--1000) of particles may be studied efficiently. The numerical method involves implicit calculation of the particle forces by minimizing an energy function and solution of a finite-difference approximation to the Stokes' equations using the Fourier--Toeplitz method. The numerical method has been implemented to run on all CRAY computers: the implementation exploits the CRAY's vectorized arithmetic, and on machines with insufficient central memory, it performs efficient disk I/O while storing most of the data on disk. Applications of the method to sedimentation of one-, two-, and many-particle systems are described. Trajectories and settling speeds for two-particle sedimentation, and settling speed for multiparticle sedimentation from initial distributions on a cubic lattice or at random give good quantitative agreement with existing theories. copyright 1988 Academic Press, Inc

  4. Cytokeratin expression of engrafted three-dimensional culture tissues using epithelial cells derived from porcine periodontal ligaments.

    Science.gov (United States)

    Yamada, Rie; Kitajima, Kayoko; Arai, Kyoko; Igarashi, Masaru

    2014-09-01

    This study investigated the differentiation and proliferation of epithelial cells derived from periodontal ligaments after three-dimensional culture using collagen gel with fibroblasts in vitro and in vivo. Epithelial cells and fibroblasts were derived from porcine periodontal ligaments. Epithelial cells were labeled using a fluorescent red membrane marker (PKH-26GL) and were seeded onto collagen gel with fibroblasts, followed by incubation in an air-liquid interface for 7 days. Three-dimensional cultures were grafted onto the backs of nude mice and removed at 1, 7, and 14 days after surgery (in vivo model). Unfixed sections (5 μm) were used to detect the presence of red fluorescent cells. Paraffin sections were analyzed histologically and immunohistochemically. Specimens were compared with three-dimensional culture tissues at 8, 14 and 21 days (in vitro model). Grafted three-dimensional cultures formed a stratified epithelial structure similar to skin in vivo. Epithelial cells were sequenced in basal-layer-like structures at 14 days in vivo. Immunohistochemical findings showed that the expression of cytokeratin was detected in the epithelial layer in in vitro and in vivo models. Ck8 + 18 + 19 was expressed in the upper epithelial layer in the in vitro model at 14 and 21 days, but not in vivo. Involucrin was expressed in the certified layers in vitro at 14 days, but not in vivo. Laminin was detected at the dermo-epidermal junction in vivo at 7 and 14 days, but not in vitro. These results suggest that differentiation of three-dimensional culture tissues differs in vivo and in vitro. © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  5. Three-Dimensional Organization of Chromosome Territories and the Human Cell Nucleus

    NARCIS (Netherlands)

    T.A. Knoch (Tobias)

    1999-01-01

    textabstractTo study the three-dimensional organization of chromosome territories and the human interphase cell nucleus we developed models, which could be compared to experiments. Despite the successful linear sequencing of the human genome its 3D-organization is widely unknown. Using Monte

  6. Three-particle forces and nuclear models

    International Nuclear Information System (INIS)

    Krutov, V.A.

    1980-01-01

    Different nuclear models accounting and unaccounting for three-particle internucleon forces (TIF) are reviewed. At present only two nuclear models use manifestly TIP: the Vautherin-Brink-Skyrme (VBS) model and the model proposed by the author of the review and called the semiphenomenological (SP) nuclear model. There is a short discussion of major drawbacks of models unaccounting for TIF: multiparticle shell model, ''superfluid model'', Harty-Fock calculations with two-particle forces, Bruckner-Hartry-Fock calculations, the relativistic self-consistent nuclear model. The VBS and SP models are discussed in detail. It is concluded, that the employment of TIF even in a very simplified form (extremely short-range) puts away a lot of problems characteristic to models limited by two-particle forces (collapse at iteratious in Hartry-Fock, simultaneous fitting of the binding energy of a nucleus and the binding energy of a nucleon, etc.) and makes it possible to obtain in a rather simple way such nuclear characteristics as nuclear binding energy, nuclear mean square root radii, nucleon density of a nucleus

  7. Modeling Dispersion of Chemical-Biological Agents in Three Dimensional Living Space

    International Nuclear Information System (INIS)

    William S. Winters

    2002-01-01

    This report documents a series of calculations designed to demonstrate Sandia's capability in modeling the dispersal of chemical and biological agents in complex three-dimensional spaces. The transport of particles representing biological agents is modeled in a single room and in several connected rooms. The influence of particle size, particle weight and injection method are studied

  8. Matrix mechanics and fluid shear stress control stem cells fate in three dimensional microenvironment.

    Science.gov (United States)

    Chen, Guobao; Lv, Yonggang; Guo, Pan; Lin, Chongwen; Zhang, Xiaomei; Yang, Li; Xu, Zhiling

    2013-07-01

    Stem cells have the ability to self-renew and to differentiate into multiple mature cell types during early life and growth. Stem cells adhesion, proliferation, migration and differentiation are affected by biochemical, mechanical and physical surface properties of the surrounding matrix in which stem cells reside and stem cells can sensitively feel and respond to the microenvironment of this matrix. More and more researches have proven that three dimensional (3D) culture can reduce the gap between cell culture and physiological environment where cells always live in vivo. This review summarized recent findings on the studies of matrix mechanics that control stem cells (primarily mesenchymal stem cells (MSCs)) fate in 3D environment, including matrix stiffness and extracellular matrix (ECM) stiffness. Considering the exchange of oxygen and nutrients in 3D culture, the effect of fluid shear stress (FSS) on fate decision of stem cells was also discussed in detail. Further, the difference of MSCs response to matrix stiffness between two dimensional (2D) and 3D conditions was compared. Finally, the mechanism of mechanotransduction of stem cells activated by matrix mechanics and FSS in 3D culture was briefly pointed out.

  9. Non-relativistic and relativistic quantum kinetic equations in nuclear physics

    International Nuclear Information System (INIS)

    Botermans, W.M.M.

    1989-01-01

    In this thesis an attempt is made to draw up a quantummechanical tranport equation for the explicit calculation oof collision processes between two (heavy) ions, by making proper approaches of the exact equations (non-rel.: N-particles Schroedinger equation; rel.: Euler-Lagrange field equations.). An important starting point in the drag-up of the theory is the behaviour of nuclear matter in equilibrium which is determined by individual as well as collective effects. The central point in this theory is the effective interaction between two nucleons both surrounded by other nucleons. In the derivation of the tranport equations use is made of the green's function formalism as developed by Schwinger and Keldys. For the Green's function kinematic equations are drawn up and are solved by choosing a proper factorization of three- and four-particle Green's functions in terms of one- and two-particle Green's functions. The necessary boundary condition is obtained by explicitly making use of Boltzmann's assumption that colliding particles are statistically uncorrelated. Finally a transport equation is obtained in which the mean field as well as the nucleon-nucleon collisions are given by the same (medium dependent) interaction. This interaction is the non-equilibrium extension of the interaction as given in the Brueckner theory of nuclear matter. Together, kinetic equation and interaction, form a self-consistent set of equations for the case of a non-relativistic as well as for the case of a relativistic starting point. (H.W.) 148 refs.; 6 figs.; 411 schemes

  10. Two-dimensional and relativistic effects in lower-hybrid current drive

    International Nuclear Information System (INIS)

    Hewett, D.; Hizanidis, K.; Krapchev, V.; Bers, A.

    1983-06-01

    We present new numerical and analytic solutions of the two-dimensional Fokker-Planck equation supplemented by a parallel quasilinear diffusion term. The results show a large enhancement of the perpendicular temperature of both the electrons resonant with the applied RF fields and the more energetic electrons in the tail. Both the RF-generated current and power dissipated are substantially increased by the perpendicular energy broadening in the resonant region. In the presence of a small DC electric field the RF current generated is very much enhanced, much more than in a simple additive fashion. In addition, we present a relativistic formulation of the two-dimensional Fokker-Planck quasilinear equation. From conservation equations, based upon this formulation, we derive the characteristics of RF current drive with energetic electrons. These show how the RF-driven current and its figure of merit (I/P/sub d/) increase with the energy of the current-carrying electrons, and that their perpendicular, random momentum must also increase

  11. Radial basis function interpolation of unstructured, three-dimensional, volumetric particle tracking velocimetry data

    International Nuclear Information System (INIS)

    Casa, L D C; Krueger, P S

    2013-01-01

    Unstructured three-dimensional fluid velocity data were interpolated using Gaussian radial basis function (RBF) interpolation. Data were generated to imitate the spatial resolution and experimental uncertainty of a typical implementation of defocusing digital particle image velocimetry. The velocity field associated with a steadily rotating infinite plate was simulated to provide a bounded, fully three-dimensional analytical solution of the Navier–Stokes equations, allowing for robust analysis of the interpolation accuracy. The spatial resolution of the data (i.e. particle density) and the number of RBFs were varied in order to assess the requirements for accurate interpolation. Interpolation constraints, including boundary conditions and continuity, were included in the error metric used for the least-squares minimization that determines the interpolation parameters to explore methods for improving RBF interpolation results. Even spacing and logarithmic spacing of RBF locations were also investigated. Interpolation accuracy was assessed using the velocity field, divergence of the velocity field, and viscous torque on the rotating boundary. The results suggest that for the present implementation, RBF spacing of 0.28 times the boundary layer thickness is sufficient for accurate interpolation, though theoretical error analysis suggests that improved RBF positioning may yield more accurate results. All RBF interpolation results were compared to standard Gaussian weighting and Taylor expansion interpolation methods. Results showed that RBF interpolation improves interpolation results compared to the Taylor expansion method by 60% to 90% based on the average squared velocity error and provides comparable velocity results to Gaussian weighted interpolation in terms of velocity error. RMS accuracy of the flow field divergence was one to two orders of magnitude better for the RBF interpolation compared to the other two methods. RBF interpolation that was applied to

  12. Ultrasound directed self-assembly of three-dimensional user-specified patterns of particles in a fluid medium

    Science.gov (United States)

    Prisbrey, M.; Greenhall, J.; Guevara Vasquez, F.; Raeymaekers, B.

    2017-01-01

    We use ultrasound directed self-assembly to organize particles dispersed in a fluid medium into a three-dimensional (3D) user-specified pattern. The technique employs ultrasound transducers that line the boundary of a fluid reservoir to create a standing ultrasound wave field. The acoustic radiation force associated with the wave field drives particles dispersed in the fluid medium into organized patterns, assuming that the particles are much smaller than the wavelength and do not interact with each other. We have theoretically derived a direct solution method to calculate the ultrasound transducer operating parameters that are required to assemble a user-specified 3D pattern of particles in a fluid reservoir of arbitrary geometry. We formulate the direct solution method as a constrained optimization problem that reduces to eigendecomposition. We experimentally validate the solution method by assembling 3D patterns of carbon nanoparticles in a water reservoir and observe good quantitative agreement between theory and experiment. Additionally, we demonstrate the versatility of the solution method by simulating ultrasound directed self-assembly of complex 3D patterns of particles. The method works for any 3D simple, closed fluid reservoir geometry in combination with any arrangement of ultrasound transducers and enables employing ultrasound directed self-assembly in a myriad of engineering applications, including biomedical and materials fabrication processes.

  13. Three-dimensional analysis of micro- and nanostructure of biomaterials and cells by method of scanning probe nanotomography

    Directory of Open Access Journals (Sweden)

    A. E. Efimov

    2017-01-01

    Full Text Available Aim: to perform a three-dimensional analysis of micro- and nanosctucture and quantitative morphological parameters of alginate spherical microcarriers and porous regenerated silk macrocarriers modifi ed by microparticles of decellularized rat liver matrix and human hepatoma HepG2 cells adhered to micro- and macro carriers. Materials and methods. Three-dimensional porous matrices made from regenerated silk by salt leaching technique and alginate spherical microcarriers fabricated by encapsulation were vitalized by human hepatome HepG2 cells. Study of three-dimensional structure of cells and micro- and macro carriers was carried out at –120 °С by scanning probe cryonanotomography technique with use of experimental setup combining cryoultramicrotome and scanning probe microscope.Results. Three-dimensional nanotomographical reconstructions of HepG2 cells adhered to macropore wall of regenerated silk macrocarrier and to spherical alginate microcarrier are obtained. Morphological parameters (mean roughness, effective surface area and autocorrelation length are determined for surfaces of macro and microcarriers and adhered cells. The determined mean roughness of alginate microcarrier surface is 76.4 ± 7.5 nm, while that of surface of macropore wall of regenerated silk macrocarrier is 133.8 ± 16.2 nm. At the same time mean roughness of cells adhered to micro- and macrocarriers are 118.5 ± 9.0 и 158.8 ± 21.6 nm correspondingly. Three-dimensional reconstructions of intracellular compartments with dimensions from 140 to 500 nm are also obtained.Conclusion. Obtained as a result of study quantitative morphology characteristics of surfaces of cell carriers and adhered cells show signifi cant degree of correlation of morphological parameters of cells and their carriers. Use of scanning probe cryonanotomography technique for three-dimensional analysis of structure and characteristics of biomaterials, cells and bio-artifi cial cellular systems

  14. Dynamics of relativistic point particles as a problem with constraints

    International Nuclear Information System (INIS)

    Todorov, I.T.

    1976-01-01

    The relativistic n-particle dynamics is studied as a problem with constraints of the type (2phisub(i)=)msub(i)sup(2)-psub(i)sup(2)+PHIsub(i)=0, i=1,...,n, (C) where PHIsub(i) are Poincare invariant functions of the particles' coordinates, momenta and spin components; PHIsib(i) is assumed to vanish asymptotically when the i-th particle coordinates tend to infinity. In the two particle case it is assumed in addition that the Poisson bracket [phi 1 , phi 2 ] vanishes on the surface (C). That allows us to give a formulation of the theory, invariant with respect to the choice of the time-parameter on each trajectory. The quantization of the relative two-particle motion is also discussed. It is pointed out that the stationary Schrodinger equation obtained in this manner is a local quasipotential equation

  15. A Three-Dimensional Numerical Study of Gas-Particle Flow and Chemical Reactions in Circulating Fluidised Bed Reactors

    DEFF Research Database (Denmark)

    Hansen, Kim Granly

    Three-dimensional Computational Fluid Dynamics (CFD) simulations of Circulating Fluidized Beds (CFB's) have been performed. The computations are performed using a 3D multiphase computational fluid dynamics code with an Eulerian description of both gas and particle phases. The turbulent motion...... implemented in the CFD code FLOTRACS-MP-3D. The decomposition reaction is studied in a 3D representation of a 0.254 m i.d. riser, which has been studied experimentally by Ouyang et al. (1993). Comparison between measured and simulated time-averaged ozone concentration at different elevations in the riser...

  16. Three-parameter relativistic dynamics. 1. Equation of motion, energy conservation

    International Nuclear Information System (INIS)

    Rogachevskii, A.G.

    1995-01-01

    A formally geometric analog of the relativistic dynamics of a point charged particle is constructed. Time as a function of the spatial coordinates is taken as the trajectory equation, i.e., the trajectory is a hypersurface in Minkowski space. The dynamics is presented. The law of open-quotes energyclose quotes conservation is examined

  17. Three-dimensional simulation of grain mixing in three different rotating drum designs for solid-state fermentation

    NARCIS (Netherlands)

    Schutyser, M.A.I.; Weber, F.J.; Briels, W.J.; Boom, R.M.; Rinzema, A.

    2002-01-01

    A previously published two-dimensional discrete particle simulation model for radial mixing behavior of various slowly rotating drums for solid-state fermentation (SSF) has been extended to a three-dimensional model that also predicts axial mixing. Radial and axial mixing characteristics were

  18. A three-dimensional strain measurement method in elastic transparent materials using tomographic particle image velocimetry.

    Directory of Open Access Journals (Sweden)

    Azuma Takahashi

    Full Text Available The mechanical interaction between blood vessels and medical devices can induce strains in these vessels. Measuring and understanding these strains is necessary to identify the causes of vascular complications. This study develops a method to measure the three-dimensional (3D distribution of strain using tomographic particle image velocimetry (Tomo-PIV and compares the measurement accuracy with the gauge strain in tensile tests.The test system for measuring 3D strain distribution consists of two cameras, a laser, a universal testing machine, an acrylic chamber with a glycerol water solution for adjusting the refractive index with the silicone, and dumbbell-shaped specimens mixed with fluorescent tracer particles. 3D images of the particles were reconstructed from 2D images using a multiplicative algebraic reconstruction technique (MART and motion tracking enhancement. Distributions of the 3D displacements were calculated using a digital volume correlation. To evaluate the accuracy of the measurement method in terms of particle density and interrogation voxel size, the gauge strain and one of the two cameras for Tomo-PIV were used as a video-extensometer in the tensile test. The results show that the optimal particle density and interrogation voxel size are 0.014 particles per pixel and 40 × 40 × 40 voxels with a 75% overlap. The maximum measurement error was maintained at less than 2.5% in the 4-mm-wide region of the specimen.We successfully developed a method to experimentally measure 3D strain distribution in an elastic silicone material using Tomo-PIV and fluorescent particles. To the best of our knowledge, this is the first report that applies Tomo-PIV to investigate 3D strain measurements in elastic materials with large deformation and validates the measurement accuracy.

  19. Optical cryptography topology based on a three-dimensional particle-like distribution and diffractive imaging.

    Science.gov (United States)

    Chen, Wen; Chen, Xudong

    2011-05-09

    In recent years, coherent diffractive imaging has been considered as a promising alternative for information retrieval instead of conventional interference methods. Coherent diffractive imaging using the X-ray light source has opened up a new research perspective for the measurement of non-crystalline and biological specimens, and can achieve unprecedentedly high resolutions. In this paper, we show how a three-dimensional (3D) particle-like distribution and coherent diffractive imaging can be applied for a study of optical cryptography. An optical multiple-random-phase-mask encoding approach is used, and the plaintext is considered as a series of particles distributed in a 3D space. A topology concept is also introduced into the proposed optical cryptosystem. During image decryption, a retrieval algorithm is developed to extract the plaintext from the ciphertexts. In addition, security and advantages of the proposed optical cryptography topology are also analyzed. © 2011 Optical Society of America

  20. Relativistic three-body model of pion-deuton elasic scattering

    International Nuclear Information System (INIS)

    Giraud, Noel.

    1978-01-01

    The Aaron-Amado-Young equations for the relativistic three-body problem are derived following the Blauckenbecker - Sugar method. The angular momentum reduction is carried out using suitable relative momenta. The pion-deuteron elastic scattering is calculated using the equations in which relativistic kinematics are retained only for the pion. After a general study of the observables in the energy range 25 to 256 MeV, detailed calculations are performed at 142 MeV [fr

  1. General-relativistic pulsar magnetospheric emission

    Science.gov (United States)

    Pétri, J.

    2018-06-01

    Most current pulsar emission models assume photon production and emission within the magnetosphere. Low-frequency radiation is preferentially produced in the vicinity of the polar caps, whereas the high-energy tail is shifted to regions closer but still inside the light cylinder. We conducted a systematic study of the merit of several popular radiation sites like the polar cap, the outer gap, and the slot gap. We computed sky maps emanating from each emission site according to a prescribed distribution function for the emitting particles made of an electron/positron mixture. Calculations are performed using a three-dimensional integration of the plasma emissivity in the vacuum electromagnetic field of a rotating and centred general-relativistic dipole. We compare Newtonian electromagnetic fields to their general-relativistic counterpart. In the latter case, light bending is also taken into account. As a typical example, light curves and sky maps are plotted for several power-law indices of the particle distribution function. The detailed pulse profiles strongly depend on the underlying assumption about the fluid motion subject to strong electromagnetic fields. This electromagnetic topology enforces the photon propagation direction directly, or indirectly, from aberration effects. We also discuss the implication of a net stellar electric charge on to sky maps. Taking into account, the electric field strongly affects the light curves originating close to the light cylinder, where the electric field strength becomes comparable to the magnetic field strength.

  2. Relativistic particle dynamics: Lagrangian proof of the no-interaction theorem

    International Nuclear Information System (INIS)

    Marmo, G.; Mukunda, N.; Sudarshan, E.C.G.

    1983-11-01

    An economical proof is given, in the Lagrangian framework, of the No Interaction Theorem of relativistic particle mechanics. It is based on the assumption that there is a Lagrangian, which if singular is allowed to lead at most to primary first class constraints. The proof works with Lagrange rather than Poisson brackets, leading to considerable simplifications compared to other proofs

  3. Classification of integrable two-dimensional models of relativistic field theory by means of computer

    International Nuclear Information System (INIS)

    Getmanov, B.S.

    1988-01-01

    The results of classification of two-dimensional relativistic field models (1) spinor; (2) essentially-nonlinear scalar) possessing higher conservation laws using the system of symbolic computer calculations are presented shortly

  4. Induction of carcinoembryonic antigen expression in a three-dimensional culture system

    Science.gov (United States)

    Jessup, J. M.; Brown, D.; Fitzgerald, W.; Ford, R. D.; Nachman, A.; Goodwin, T. J.; Spaulding, G.

    1994-01-01

    MIP-101 is a poorly differentiated human colon carcinoma cell line established from ascites that produces minimal amounts of carcinoembryonic antigen (CEA), a 180 kDa glycoprotein tumor marker, and nonspecific cross-reacting antigen (NCA), a related protein that has 50 and 90 kDa isoforms, in vitro in monolayer culture. MIP-101 produces CEA when implanted into the peritoneum of nude mice but not when implanted into subcutaneous tissue. We tested whether MIP-101 cells may be induced to express CEA when cultured on microcarrier beads in three-dimensional cultures, either in static cultures as non-adherent aggregates or under dynamic conditions in a NASA-designed low shear stress bioreactor. MIP- 101 cells proliferated well under all three conditions and increased CEA and NCA production 3 - 4 fold when grown in three-dimensional cultures compared to MIP-101 cells growing logarithmically in monolayers. These results suggest that three-dimensional growth in vitro simulates tumor function in vivo and that three-dimensional growth by itself may enhance production of molecules that are associated with the metastatic process.

  5. Three-dimensional current flow and particle precipitation in a westward travelling surge (observed during the barium-GEOS rocket experiment)

    International Nuclear Information System (INIS)

    Opgenoorth, H.J.; Pellinen, R.J.; Baumjohann, W.; Nielsen, E.; Marklund, G.; Eliasson, L.

    1983-01-01

    During the Barium-GEOS rocket experiment on September 24, 1979 the passage of a westward travelling surge (WTS) was observed over Scandinavia. Extended instrument networks in that area, viz., the Scandinavian Magnetometer Array, the STARE radars, all-sky cameras, and riometers, allowed simultaneous observation of the two-dimensional character of magnetic and electric field disturbances and particle precipitation associated with the auroral feature. By combination of the different datasets and additional information from particle and electric field measurements aboard the Barium-GEOS rocket it was possible to derive the two-dimensional distribution of ionospheric electric fields and conductivities and to model the three-dimensional current flow in the vicinity of the westward travelling surge. The main feature of the resulting model current system is the presence of a localized upward field-aligned current directed out of the head of the surge and fed by a westward electrojet, which is composed of both Hall and Pedersen currents. Secondary ionospheric currents, e.g. a counterclockwise loop of mainly Hall currents around the leading edge of the surge, are found to be responsible for most of the transient effects observed by ground-based magnetometers as the WTS passed overhead. The most energetic particle precipitation as inferred from cosmic noise absorption measurements and triangulation of auroral arc altitudes is found to be confined to the leading part and central regions of the surge and to travel westward with the visual auroral form

  6. Three dimensional vortices and interfaces in Hele-Shaw cells

    International Nuclear Information System (INIS)

    Pumir, A.

    1987-06-01

    A model of nonviscous flow, based on the Biot-Savart equations is used to examine the existence of singularities in three dimensional, incompressible, hydrodynamic equations. The results suggest a fairly simple physical mechanism, which could lead to the formation of singularities in the nonviscous case: two vortex tubes with opposite circulations pair up and stretch each other, until the radii of the vortex cores become extremely small, causing a divergence of the vorticity. The cases of a perfect and a slightly viscous fluid are considered. The results are unclear as to whether the vorticity of a slightly viscous fluid can become infinite or not, and whether singularities exist. The dynamics of hydrodynamic interfaces are also investigated. The propagation of bubbles in a slightly viscous fluid, in a Hele-Shaw cell are described [fr

  7. Physical equivalence of three forms of relativistic dynamics and addition of interactions in the front and instant forms

    International Nuclear Information System (INIS)

    Sokolov, S.N.

    1977-01-01

    The point, instant and front forms of the relativistic Hamiltonian theory are shown to be S-matrix equivalent in the general case (of many channels and particles with spin). The corresponding transformations are found. The problem of relativistic addition of the direct interactions is solved for the front and instant forms of dynamics

  8. Energy penetration into arrays of aligned nanowires irradiated with relativistic intensities: Scaling to terabar pressures.

    Science.gov (United States)

    Bargsten, Clayton; Hollinger, Reed; Capeluto, Maria Gabriela; Kaymak, Vural; Pukhov, Alexander; Wang, Shoujun; Rockwood, Alex; Wang, Yong; Keiss, David; Tommasini, Riccardo; London, Richard; Park, Jaebum; Busquet, Michel; Klapisch, Marcel; Shlyaptsev, Vyacheslav N; Rocca, Jorge J

    2017-01-01

    Ultrahigh-energy density (UHED) matter, characterized by energy densities >1 × 10 8 J cm -3 and pressures greater than a gigabar, is encountered in the center of stars and inertial confinement fusion capsules driven by the world's largest lasers. Similar conditions can be obtained with compact, ultrahigh contrast, femtosecond lasers focused to relativistic intensities onto targets composed of aligned nanowire arrays. We report the measurement of the key physical process in determining the energy density deposited in high-aspect-ratio nanowire array plasmas: the energy penetration. By monitoring the x-ray emission from buried Co tracer segments in Ni nanowire arrays irradiated at an intensity of 4 × 10 19 W cm -2 , we demonstrate energy penetration depths of several micrometers, leading to UHED plasmas of that size. Relativistic three-dimensional particle-in-cell simulations, validated by these measurements, predict that irradiation of nanostructures at intensities of >1 × 10 22 W cm -2 will lead to a virtually unexplored extreme UHED plasma regime characterized by energy densities in excess of 8 × 10 10 J cm -3 , equivalent to a pressure of 0.35 Tbar.

  9. Three-dimensional growth patterns of various human tumor cell lines in simulated microgravity of a NASA bioreactor.

    Science.gov (United States)

    Ingram, M; Techy, G B; Saroufeem, R; Yazan, O; Narayan, K S; Goodwin, T J; Spaulding, G F

    1997-06-01

    Growth patterns of a number of human tumor cell lines that from three-dimensional structures of various architectures when cultured without carrier beads in a NASA rotary cell culture system are described and illustrated. The culture system, which was designed to mimic microgravity, maintained cells in suspension under very low-shear stress throughout culture. Spheroid (particulate) production occurred within a few hours after culture was started, and spheroids increased in size by cell division and fusion of small spheroids, usually stabilizing at a spheroid diameter of about 0.5 mm. Architecture of spheroids varied with cell type. Cellular interactions that occurred in spheroids resulted in conformation and shape changes of cells, and some cell lines produced complex, epithelial-like architectures. Expression of the cell adhesion molecules, CD44 and E cadherin, was upregulated in the three-dimensional constructs. Coculture of fibroblast spheroids with PC3 prostate cancer cells induced tenascin expression by the fibroblasts underlying the adherent prostate epithelial cells. Invasion of the fibroblast spheroids by the malignant epithelium was also demonstrated.

  10. Four-dimensional image display for associated particle imaging

    International Nuclear Information System (INIS)

    Headley, G.; Beyerle, A.; Durkee, R.; Hurley, P.; Tunnell, L.

    1994-01-01

    Associated particle imaging (API) is a three-dimensional neutron gamma imaging technique which provides both spatial and spectral information about an unknown. A local area network consisting of a UNIX fileserver and multiple DOS workstations has been chosen to perform the data acquisition and display functions. The data are acquired with a CAMAC system, stored in list mode, and sorted on the fileserver for display on the DOS workstations. Three of the display PCs, interacting with the fileserver, provide coordinated views as the operator ''slices'' the image. The operator has a choice of: a one-dimensional shadowgram from any side, two-dimensional shadowgrams from any side; a three-dimensional view (either perspective projection or stereoscopic). A common color scheme is used to carry energy information into the spatial images. ((orig.))

  11. Mesenchymal Stem Cells Sense Three Dimensional Type I Collagen through Discoidin Domain Receptor 1.

    Science.gov (United States)

    Lund, A W; Stegemann, J P; Plopper, G E

    2009-01-01

    The extracellular matrix provides structural and organizational cues for tissue development and defines and maintains cellular phenotype during cell fate determination. Multipotent mesenchymal stem cells use this matrix to tightly regulate the balance between their differentiation potential and self-renewal in the native niche. When understood, the mechanisms that govern cell-matrix crosstalk during differentiation will allow for efficient engineering of natural and synthetic matrices to specifically direct and maintain stem cell phenotype. This work identifies the discoidin domain receptor 1 (DDR1), a collagen activated receptor tyrosine kinase, as a potential link through which stem cells sense and respond to the 3D organization of their extracellular matrix microenvironment. DDR1 is dependent upon both the structure and proteolytic state of its collagen ligand and is specifically expressed and localized in three dimensional type I collagen culture. Inhibition of DDR1 expression results in decreased osteogenic potential, increased cell spreading, stress fiber formation and ERK1/2 phosphorylation. Additionally, loss of DDR1 activity alters the cell-mediated organization of the naïve type I collagen matrix. Taken together, these results demonstrate a role for DDR1 in the stem cell response to and interaction with three dimensional type I collagen. Dynamic changes in cell shape in 3D culture and the tuning of the local ECM microstructure, directs crosstalk between DDR1 and two dimensional mechanisms of osteogenesis that can alter their traditional roles.

  12. Comprehensive analysis of signal transduction in three-dimensional ECM-based tumor cell cultures

    Directory of Open Access Journals (Sweden)

    Iris Eke

    2015-11-01

    Full Text Available Analysis of signal transduction and protein phosphorylation is fundamental to understand physiological and pathological cell behavior as well as identification of novel therapeutic targets. Despite the fact that more physiological three-dimensional cell culture assays are increasingly used, particularly proteomics and phosphoproteomics remain challenging due to easy, robust and reproducible sample preparation. Here, we present an easy-to-perform, reliable and time-efficient method for the production of 3D cell lysates without compromising cell adhesion before cell lysis. The samples can be used for Western blotting as well as phosphoproteome array technology. This technique would be of interest for researchers working in all fields of biology and drug development.

  13. Three-dimensional organoid culture reveals involvement of Wnt/β-catenin pathway in proliferation of bladder cancer cells.

    Science.gov (United States)

    Yoshida, Takahiro; Sopko, Nikolai A; Kates, Max; Liu, Xiaopu; Joice, Gregory; McConkey, David J; Bivalacqua, Trinity J

    2018-02-16

    There has been increasing awareness of the importance of three-dimensional culture of cancer cells. Tumor cells growing as multicellular spheroids in three-dimensional culture, alternatively called organoids, are widely believed to more closely mimic solid tumors in situ . Previous studies concluded that the Wnt/β-catenin pathway is required for regeneration of the normal urothelium after injury and that β-catenin is upregulated in human bladder cancers, but no clear evidence has been advanced to support the idea that the Wnt/β-catenin pathway is directly involved in deregulated proliferation and the other malignant characteristics of bladder cancer cells. Here we report that the Wnt/β-catenin pathway activator, CHIR99021, promoted proliferation of established human bladder cancer cell lines when they were grown in organoid culture but not when they were grown in conventional adherent cultures. CHIR99021 activated Wnt/β-catenin pathway in bladder cancer cell lines in organoid culture. CHIR99021 also stimulated proliferation and the Wnt/b-catenin pathway in primary human bladder cancer organoids. RNAi-mediated knockdown of β-catenin blocked growth of organoids. The effects of CHIR99021 were associated with decreased expression of the urothelial terminal differentiation marker, cytokeratin 20. Our data suggest that the Wnt/β-catenin pathway is required for the proliferation of bladder cancer cells in three-dimensional organoid culture and provide a concrete example of why organoid culture is important for cancer research.

  14. The fabrication and cell culture of three-dimensional rolled scaffolds with complex micro-architectures

    International Nuclear Information System (INIS)

    Liu Yaxiong; Li Xiao; Qu Xiaoli; Zhu Lin; He Jiankang; Zhao Qian; Wu Wanquan; Li Dichen

    2012-01-01

    Cell cultures for tissue engineering are traditionally prepared on two-dimensional or three-dimensional scaffolds with simple pores; however, this limits mass transportation, which is necessary for cell viability and function. In this paper, an innovative method is proposed for fabricating porous scaffolds with designed complex micro-architectures. Channels devised by computer-aided design were used to simulate features of blood vessels in native rat liver. Rapid prototyping and microreplication were used to produce a negative polydimethylsiloxane mold, and then a planar porous scaffold with predefined microchannel parameters was obtained by freeze-drying a silk fibroin/gelatin solution of an optimized concentration. After seeding with rat primary hepatocytes, the planar scaffold was rolled up to build spatial channels. By reconstructing the three-dimensional channel model in the scaffold in the form of micro-computed topography data and observing the cross-sections of the scroll, we confirmed that the bent channels were still interconnected, with restricted deviations. A comparison of the primary hepatocyte culture in the scaffolds with and without the devised channels proved that our design influenced cell organization and improved cell survival and proliferation. This method can be used for the construction of complex tissues for implantation and for culturing cells in vitro for biological tests and observations.

  15. Three-Dimensional Organization of Chromosome Territories in the Human Interphase Nucleus

    NARCIS (Netherlands)

    T.A. Knoch (Tobias); J. Langowski (Jörg)

    1999-01-01

    textabstractDespite the successful linear sequencing of the human genome its three-dimensional structure is widely unknown. The regulation of genes has been shown to be connected closely to the three-dimensional organization of the genome in the cell nucleus. The nucleus of the cell has for a long

  16. Three-dimensional hydrogel cell culture systems for modeling neural tissue

    Science.gov (United States)

    Frampton, John

    Two-dimensional (2-D) neural cell culture systems have served as physiological models for understanding the cellular and molecular events that underlie responses to physical and chemical stimuli, control sensory and motor function, and lead to the development of neurological diseases. However, the development of three-dimensional (3-D) cell culture systems will be essential for the advancement of experimental research in a variety of fields including tissue engineering, chemical transport and delivery, cell growth, and cell-cell communication. In 3-D cell culture, cells are provided with an environment similar to tissue, in which they are surrounded on all sides by other cells, structural molecules and adhesion ligands. Cells grown in 3-D culture systems display morphologies and functions more similar to those observed in vivo, and can be cultured in such a way as to recapitulate the structural organization and biological properties of tissue. This thesis describes a hydrogel-based culture system, capable of supporting the growth and function of several neural cell types in 3-D. Alginate hydrogels were characterized in terms of their biomechanical and biochemical properties and were functionalized by covalent attachment of whole proteins and peptide epitopes. Methods were developed for rapid cross-linking of alginate hydrogels, thus permitting the incorporation of cells into 3-D scaffolds without adversely affecting cell viability or function. A variety of neural cell types were tested including astrocytes, microglia, and neurons. Cells remained viable and functional for longer than two weeks in culture and displayed process outgrowth in 3-D. Cell constructs were created that varied in cell density, type and organization, providing experimental flexibility for studying cell interactions and behavior. In one set of experiments, 3-D glial-endothelial cell co-cultures were used to model blood-brain barrier (BBB) structure and function. This co-culture system was

  17. A comprehensive study of MPI parallelism in three-dimensional discrete element method (DEM) simulation of complex-shaped granular particles

    Science.gov (United States)

    Yan, Beichuan; Regueiro, Richard A.

    2018-02-01

    A three-dimensional (3D) DEM code for simulating complex-shaped granular particles is parallelized using message-passing interface (MPI). The concepts of link-block, ghost/border layer, and migration layer are put forward for design of the parallel algorithm, and theoretical scalability function of 3-D DEM scalability and memory usage is derived. Many performance-critical implementation details are managed optimally to achieve high performance and scalability, such as: minimizing communication overhead, maintaining dynamic load balance, handling particle migrations across block borders, transmitting C++ dynamic objects of particles between MPI processes efficiently, eliminating redundant contact information between adjacent MPI processes. The code executes on multiple US Department of Defense (DoD) supercomputers and tests up to 2048 compute nodes for simulating 10 million three-axis ellipsoidal particles. Performance analyses of the code including speedup, efficiency, scalability, and granularity across five orders of magnitude of simulation scale (number of particles) are provided, and they demonstrate high speedup and excellent scalability. It is also discovered that communication time is a decreasing function of the number of compute nodes in strong scaling measurements. The code's capability of simulating a large number of complex-shaped particles on modern supercomputers will be of value in both laboratory studies on micromechanical properties of granular materials and many realistic engineering applications involving granular materials.

  18. Three-dimensional structure of the γ-secretase complex

    International Nuclear Information System (INIS)

    Ogura, Toshihiko; Mio, Kazuhiro; Hayashi, Ikuo; Miyashita, Hiroyuki; Fukuda, Rie; Kopan, Raphael; Kodama, Tatsuhiko; Hamakubo, Takao; Iwastubo, Takeshi; Tomita, Taisuke; Sato, Chikara

    2006-01-01

    γ-Secretase belongs to an atypical class of aspartic proteases that hydrolyzes peptide bonds within the transmembrane domain of substrates, including amyloid-β precursor protein and Notch. γ-Secretase is comprised of presenilin, nicastrin, APH-1, and PEN-2 which form a large multimeric membrane protein complex, the three-dimensional structure of which is unknown. To gain insight into the structure of this complex enzyme, we purified functional γ-secretase complex reconstituted in Sf9 cells and analyzed it using negative stain electron microscopy and 3D reconstruction techniques. Analysis of 2341 negatively stained particle images resulted in the three-dimensional representation of γ-secretase at a resolution of 48 A. The structure occupies a volume of 560 x 320 x 240 A and resembles a flat heart comprised of two oppositely faced, dimpled domains. A low density space containing multiple pores resides between the domains. Some of the dimples in the putative transmembrane region may house the catalytic site. The large dimensions are consistent with the observation that γ-secretase activity resides within a high molecular weight complex

  19. Microfluidic engineered high cell density three-dimensional neural cultures

    Science.gov (United States)

    Cullen, D. Kacy; Vukasinovic, Jelena; Glezer, Ari; La Placa, Michelle C.

    2007-06-01

    Three-dimensional (3D) neural cultures with cells distributed throughout a thick, bioactive protein scaffold may better represent neurobiological phenomena than planar correlates lacking matrix support. Neural cells in vivo interact within a complex, multicellular environment with tightly coupled 3D cell-cell/cell-matrix interactions; however, thick 3D neural cultures at cell densities approaching that of brain rapidly decay, presumably due to diffusion limited interstitial mass transport. To address this issue, we have developed a novel perfusion platform that utilizes forced intercellular convection to enhance mass transport. First, we demonstrated that in thick (>500 µm) 3D neural cultures supported by passive diffusion, cell densities =104 cells mm-3), continuous medium perfusion at 2.0-11.0 µL min-1 improved viability compared to non-perfused cultures (p death and matrix degradation. In perfused cultures, survival was dependent on proximity to the perfusion source at 2.00-6.25 µL min-1 (p 90% viability in both neuronal cultures and neuronal-astrocytic co-cultures. This work demonstrates the utility of forced interstitial convection in improving the survival of high cell density 3D engineered neural constructs and may aid in the development of novel tissue-engineered systems reconstituting 3D cell-cell/cell-matrix interactions.

  20. Cell culture for three-dimensional modeling in rotating-wall vessels: an application of simulated microgravity

    Science.gov (United States)

    Schwarz, R. P.; Goodwin, T. J.; Wolf, D. A.

    1992-01-01

    High-density, three-dimensional cell cultures are difficult to grow in vitro. The rotating-wall vessel (RWV) described here has cultured BHK-21 cells to a density of 1.1 X 10(7) cells/ml. Cells on microcarriers were observed to grow with enhanced bridging in this batch culture system. The RWV is a horizontally rotated tissue culture vessel with silicon membrane oxygenation. This design results in a low-turbulence, low-shear cell culture environment with abundant oxygenation. The RWV has the potential to culture a wide variety of normal and neoplastic cells.

  1. Spacetime alternatives in the quantum mechanics of a relativistic particle

    International Nuclear Information System (INIS)

    Whelan, J.T.

    1994-01-01

    Hartle's generalized quantum mechanics formalism is used to examine spacetime coarse grainings, i.e., sets of alternatives defined with respect to a region extended in time as well as space, in the quantum mechanics of a free relativistic particle. For a simple coarse graining and suitable initial conditions, tractable formulas are found for branch wave functions. Despite the nonlocality of the positive-definite version of the Klein-Gordon inner product, which means that nonoverlapping branches are not sufficient to imply decoherence, some initial conditions are found to give decoherence and allow the consistent assignment of probabilities

  2. Relativistic stellar dynamics

    International Nuclear Information System (INIS)

    Contopoulos, G.

    1983-01-01

    In this paper, three main areas of relativistic stellar dynamics are reviewed: (a) The dynamics of clusters, or nuclei of galaxies, of very high density; (b) The dynamics of systems containing a massive black hole; and (c) The dynamics of particles (and photons) in an expanding Universe. The emphasis is on the use of orbit perturbations. (Auth.)

  3. On classical solutions of the relativistic Vlasov-Klein-Gordon system

    Directory of Open Access Journals (Sweden)

    Michael Kunzinger

    2005-01-01

    Full Text Available We consider a collisionless ensemble of classical particles coupled with a Klein-Gordon field. For the resulting nonlinear system of partial differential equations, the relativistic Vlasov-Klein-Gordon system, we prove local-in-time existence of classical solutions and a continuation criterion which says that a solution can blow up only if the particle momenta become large. We also show that classical solutions are global in time in the one-dimensional case.

  4. Photogrammetry of the three-dimensional shape and texture of a nanoscale particle using scanning electron microscopy and free software

    International Nuclear Information System (INIS)

    Gontard, Lionel C.; Schierholz, Roland; Yu, Shicheng; Cintas, Jesús; Dunin-Borkowski, Rafal E.

    2016-01-01

    We apply photogrammetry in a scanning electron microscope (SEM) to study the three-dimensional shape and surface texture of a nanoscale LiTi_2(PO_4)_3 particle. We highlight the fact that the technique can be applied non-invasively in any SEM using free software (freeware) and does not require special sample preparation. Three-dimensional information is obtained in the form of a surface mesh, with the texture of the sample stored as a separate two-dimensional image (referred to as a UV Map). The mesh can be used to measure parameters such as surface area, volume, moment of inertia and center of mass, while the UV map can be used to study the surface texture using conventional image processing techniques. We also illustrate the use of 3D printing to visualize the reconstructed model. - Highlights: • 3D shape and surface texture of a nanoscale LiTi_2(PO_4)_3 particle. • The technique can be applied non-invasively in any SEM using freeware software. • The mesh can be used to measure parameters such as surface area, volume, moment of inertia and center of mass. • The UV map can be processed using 2D image processing software.

  5. Photogrammetry of the three-dimensional shape and texture of a nanoscale particle using scanning electron microscopy and free software

    Energy Technology Data Exchange (ETDEWEB)

    Gontard, Lionel C., E-mail: lionelcg@gmail.com [Departamento de Ciencia de los Materiales e Ingeniería Metalúrgica y Química Inorgánica, Universidad de Cádiz, Puerto Real 11510 (Spain); Faico PCT Cartuja. Edif. TI Marie Curie, C/ Leonardo da Vinci 18, 4a Planta, 41092 Sevilla (Spain); Schierholz, Roland; Yu, Shicheng [Institute of Energy and Climate Research, Fundamental Electrochemistry (IEK-9), Forschungszentrum Jülich, D-52425 Jülich (Germany); Cintas, Jesús [Servicio de Microscopía Centro de Investigación, Tecnología e Innovación (CITIUS), Universidad de Sevilla, Av. Reina Mercedes 4b, 41012 Sevilla (Spain); Dunin-Borkowski, Rafal E. [Ernst Ruska-Centre for Microscopy and Spectroscopy with Electrons and Peter Grünberg Institute, Forschungszentrum Jülich, D-52425 Jülich (Germany)

    2016-10-15

    We apply photogrammetry in a scanning electron microscope (SEM) to study the three-dimensional shape and surface texture of a nanoscale LiTi{sub 2}(PO{sub 4}){sub 3} particle. We highlight the fact that the technique can be applied non-invasively in any SEM using free software (freeware) and does not require special sample preparation. Three-dimensional information is obtained in the form of a surface mesh, with the texture of the sample stored as a separate two-dimensional image (referred to as a UV Map). The mesh can be used to measure parameters such as surface area, volume, moment of inertia and center of mass, while the UV map can be used to study the surface texture using conventional image processing techniques. We also illustrate the use of 3D printing to visualize the reconstructed model. - Highlights: • 3D shape and surface texture of a nanoscale LiTi{sub 2}(PO{sub 4}){sub 3} particle. • The technique can be applied non-invasively in any SEM using freeware software. • The mesh can be used to measure parameters such as surface area, volume, moment of inertia and center of mass. • The UV map can be processed using 2D image processing software.

  6. Toward a unified theory of the radiation by relativistic particles in crystals

    International Nuclear Information System (INIS)

    Beloshitskii, V.V.; Kalinichenko, V.F.

    1989-01-01

    A quantum theory of the electromagnetic emission by relativistic particles incorporating channeling and the thermal vibrations of the crystal nuclei is derived. A general expression for the emission probability is found after an average over the initial polarizations of the particles and a summation over the final polarizations of the particles and over the polarizations of the photons. An average is carried out over the crystal states of the nuclei in the cases with and without excitation of phonons. The total emission is made up of channeling emission and bremsstrahlung, which are related to each other. During scattering by thermal vibrations, incoherent bremsstrahlung is produced. Some particular cases which determine the properties of the emission in the case of channeling are derived from the general expression and analyzed

  7. Non-relativistic conformal symmetries and Newton-Cartan structures

    International Nuclear Information System (INIS)

    Duval, C; Horvathy, P A

    2009-01-01

    This paper provides us with a unifying classification of the conformal infinitesimal symmetries of non-relativistic Newton-Cartan spacetime. The Lie algebras of non-relativistic conformal transformations are introduced via the Galilei structure. They form a family of infinite-dimensional Lie algebras labeled by a rational 'dynamical exponent', z. The Schroedinger-Virasoro algebra of Henkel et al corresponds to z = 2. Viewed as projective Newton-Cartan symmetries, they yield, for timelike geodesics, the usual Schroedinger Lie algebra, for which z = 2. For lightlike geodesics, they yield, in turn, the Conformal Galilean Algebra (CGA) of Lukierski, Stichel and Zakrzewski (alias 'alt' of Henkel), with z = 1. Physical systems realizing these symmetries include, e.g. classical systems of massive and massless non-relativistic particles, and also hydrodynamics, as well as Galilean electromagnetism.

  8. Digital stereo-holographic microscopy for studying three-dimensional particle dynamics

    Science.gov (United States)

    Byeon, Hyeokjun; Go, Taesik; Lee, Sang Joon

    2018-06-01

    A digital stereo-holographic microscopy (DsHM) with two viewing angles is proposed to measure 3D information of microscale particles. This approach includes two volumetric recordings and numerical reconstruction, and it involves the combination of separately reconstructed holograms. The 3D positional information of a particle was determined by searching the center of the overlapped reconstructed volume. After confirming the proposed technique using static spherical particles, the 3D information of moving particles suspended in a Hagen-Poiseiulle flow was successfully obtained. Moreover, the 3D information of nonspherical particles, including ellipsoidal particles and red blood cells, were measured using the proposed technique. In addition to 3D positional information, the orientation and shape of the test samples were obtained from the plane images by slicing the overlapped volume perpendicular to the directions of the image recordings. This DsHM technique will be useful in analyzing the 3D dynamic behavior of various nonspherical particles, which cannot be measured by conventional digital holographic microscopy.

  9. Transition in the equilibrium distribution function of relativistic particles.

    Science.gov (United States)

    Mendoza, M; Araújo, N A M; Succi, S; Herrmann, H J

    2012-01-01

    We analyze a transition from single peaked to bimodal velocity distribution in a relativistic fluid under increasing temperature, in contrast with a non-relativistic gas, where only a monotonic broadening of the bell-shaped distribution is observed. Such transition results from the interplay between the raise in thermal energy and the constraint of maximum velocity imposed by the speed of light. We study the Bose-Einstein, the Fermi-Dirac, and the Maxwell-Jüttner distributions, and show that they all exhibit the same qualitative behavior. We characterize the nature of the transition in the framework of critical phenomena and show that it is either continuous or discontinuous, depending on the group velocity. We analyze the transition in one, two, and three dimensions, with special emphasis on twodimensions, for which a possible experiment in graphene, based on the measurement of the Johnson-Nyquist noise, is proposed.

  10. On the model of the relativistic particle with curvature and torsion

    International Nuclear Information System (INIS)

    Nesterenko, V.V.

    1992-01-01

    Two integrals along the world trajectory of its curvature and torsion are added to the standard action for the point-like spinless relativistic particle. This enables one to quantize the model canonically and to derive exactly the relation between the spin and mass of the states. 10 refs

  11. Deep processes in non-relativistic confining potentials

    International Nuclear Information System (INIS)

    Fishbane, P.M.; Grisaru, M.T.

    1978-01-01

    The authors study deep inelastic and hard scattering processes for non-relativistic particles confined in deep potentials. The mechanisms by which the effects of confinement disappear and the particles scatter as if free are useful in understanding the analogous results for a relativistic field theory. (Auth.)

  12. Direct Conversion of Equine Adipose-Derived Stem Cells into Induced Neuronal Cells Is Enhanced in Three-Dimensional Culture.

    Science.gov (United States)

    Petersen, Gayle F; Hilbert, Bryan J; Trope, Gareth D; Kalle, Wouter H J; Strappe, Padraig M

    2015-12-01

    The ability to culture neurons from horses may allow further investigation into equine neurological disorders. In this study, we demonstrate the generation of induced neuronal cells from equine adipose-derived stem cells (EADSCs) using a combination of lentiviral vector expression of the neuronal transcription factors Brn2, Ascl1, Myt1l (BAM) and NeuroD1 and a defined chemical induction medium, with βIII-tubulin-positive induced neuronal cells displaying a distinct neuronal morphology of rounded and compact cell bodies, extensive neurite outgrowth, and branching of processes. Furthermore, we investigated the effects of dimensionality on neuronal transdifferentiation, comparing conventional two-dimensional (2D) monolayer culture against three-dimensional (3D) culture on a porous polystyrene scaffold. Neuronal transdifferentiation was enhanced in 3D culture, with evenly distributed cells located on the surface and throughout the scaffold. Transdifferentiation efficiency was increased in 3D culture, with an increase in mean percent conversion of more than 100% compared to 2D culture. Additionally, induced neuronal cells were shown to transit through a Nestin-positive precursor state, with MAP2 and Synapsin 2 expression significantly increased in 3D culture. These findings will help to increase our understanding of equine neuropathogenesis, with prospective roles in disease modeling, drug screening, and cellular replacement for treatment of equine neurological disorders.

  13. Gyrotactic suppression and emergence of chaotic trajectories of swimming particles in three-dimensional flows

    Science.gov (United States)

    Richardson, S. I. Heath; Baggaley, A. W.; Hill, N. A.

    2018-02-01

    We study the effects of imposed three-dimensional flows on the trajectories and mixing of gyrotactic swimming microorganisms and identify phenomena not seen in flows restricted to two dimensions. Through numerical simulation of Taylor-Green and Arnold-Beltrami-Childress (ABC) flows, we explore the role that the flow and the cell shape play in determining the long-term configuration of the cells' trajectories, which often take the form of multiple sinuous and helical "plumelike" structures, even in the chaotic ABC flow. This gyrotactic suppression of Lagrangian chaos persists even in the presence of random noise. Analytical solutions for a number of cases reveal the how plumes form and the nature of the competition between torques acting on individual cells. Furthermore, studies of Lyapunov exponents reveal that, as the ratio of cell swimming speed relative to the flow speed increases from zero, the initial chaotic trajectories are first suppressed and then give way to a second unexpected window of chaotic trajectories at speeds greater than unity, before suppression of chaos at high relative swimming speeds.

  14. Three-dimensional ionic conduction in the strained electrolytes of solid oxide fuel cells

    International Nuclear Information System (INIS)

    Han, Yupei; Zou, Minda; Lv, Weiqiang; He, Weidong; Mao, Yiwu; Wang, Wei

    2016-01-01

    Flexible power sources including fuel cells and batteries are the key to realizing flexible electronic devices with pronounced foldability. To understand the bending effects in these devices, theoretical analysis on three-dimensional (3-D) lattice bending is necessary. In this report, we derive a 3-D analytical model to analyze the effects of electrolyte crystal bending on ionic conductivity in flexible solid-state batteries/fuel cells. By employing solid oxide fuel cells as a materials' platform, the intrinsic parameters of bent electrolyte materials, including lattice constant, Young's modulus, and Poisson ratio, are evaluated. Our work facilitates the rational design of highly efficient flexible electrolytes for high-performance flexible device applications.

  15. Preservation of three-dimensional spatial structure in the gut microbiome.

    Directory of Open Access Journals (Sweden)

    Yuko Hasegawa

    Full Text Available Preservation of three-dimensional structure in the gut is necessary in order to analyze the spatial organization of the gut microbiota and gut luminal contents. In this study, we evaluated preparation methods for mouse gut with the goal of preserving micron-scale spatial structure while performing fluorescence imaging assays. Our evaluation of embedding methods showed that commonly used media such as Tissue-Tek Optimal Cutting Temperature (OCT compound, paraffin, and polyester waxes resulted in redistribution of luminal contents. By contrast, a hydrophilic methacrylate resin, Technovit H8100, preserved three-dimensional organization. Our mouse intestinal preparation protocol optimized using the Technovit H8100 embedding method was compatible with microbial fluorescence in situ hybridization (FISH and other labeling techniques, including immunostaining and staining with both wheat germ agglutinin (WGA and 4', 6-diamidino-2-phenylindole (DAPI. Mucus could be visualized whether the sample was fixed with paraformaldehyde (PFA or with Carnoy's fixative. The protocol optimized in this study enabled simultaneous visualization of micron-scale spatial patterns formed by microbial cells in the mouse intestines along with biogeographical landmarks such as host-derived mucus and food particles.

  16. Learning the Cell Structures with Three-Dimensional Models: Students' Achievement by Methods, Type of School and Questions' Cognitive Level

    Science.gov (United States)

    Lazarowitz, Reuven; Naim, Raphael

    2014-01-01

    The cell topic was taught to 9th-grade students in three modes of instruction: (a) students "hands-on," who constructed three-dimensional cell organelles and macromolecules during the learning process; (b) teacher demonstration of the three-dimensional model of the cell structures; and (c) teaching the cell topic with the regular…

  17. Three dimensional δf simulations of beams in the SSC

    International Nuclear Information System (INIS)

    Koga, J.; Tajima, T.; Machida, S.

    1993-01-01

    A three dimensional δf strong-strong algorithm has been developed to apply to the study of such effects as space charge and beam-beam interaction phenomena in the Superconducting Super Collider (SSC). The algorithm is obtained from the merging of the particle tracking code Simpsons used for 3 dimensional space charge effects and a δf code. The δf method is used to follow the evolution of the non-gaussian part of the beam distribution. The advantages of this method are twofold. First, the Simpsons code utilizes a realistic accelerator model including synchrotron oscillations and energy ramping in 6 dimensional phase space with electromagnetic fields of the beams calculated using a realistic 3 dimensional field solver. Second, the beams are evolving in the fully self-consistent strong-strong sense with finite particle fluctuation noise is greatly reduced as opposed to the weak-strong models where one beam is fixed

  18. Three dimensional [delta]f simulations of beams in the SSC

    Energy Technology Data Exchange (ETDEWEB)

    Koga, J.; Tajima, T. (Texas Univ., Austin, TX (United States). Inst. for Fusion Studies); Machida, S. (Superconducting Super Collider Lab., Dallas, TX (United States))

    1993-02-01

    A three dimensional [delta]f strong-strong algorithm has been developed to apply to the study of such effects as space charge and beam-beam interaction phenomena in the Superconducting Super Collider (SSC). The algorithm is obtained from the merging of the particle tracking code Simpsons used for 3-dimensional space charge effects and a [delta]f code. The [delta]f method is used to follow the evolution of the non-gaussian part of the beam distribution. The advantages of this method are twofold. First, the Simpsons code utilizes a realistic accelerator model including synchrotron oscillations and energy ramping in 6-dimensional phase space with electromagnetic fields of the beams calculated using a realistic 3-dimensional field solver. Second, the beams are evolving in the fully self-consistent strong-strong sense where finite particle fluctuation noise is greatly reduced as opposed to the weak-strong models where one beam is fixed.

  19. Three dimensional {delta}f simulations of beams in the SSC

    Energy Technology Data Exchange (ETDEWEB)

    Koga, J.; Tajima, T. [Texas Univ., Austin, TX (United States). Inst. for Fusion Studies; Machida, S. [Superconducting Super Collider Lab., Dallas, TX (United States)

    1993-02-01

    A three dimensional {delta}f strong-strong algorithm has been developed to apply to the study of such effects as space charge and beam-beam interaction phenomena in the Superconducting Super Collider (SSC). The algorithm is obtained from the merging of the particle tracking code Simpsons used for 3-dimensional space charge effects and a {delta}f code. The {delta}f method is used to follow the evolution of the non-gaussian part of the beam distribution. The advantages of this method are twofold. First, the Simpsons code utilizes a realistic accelerator model including synchrotron oscillations and energy ramping in 6-dimensional phase space with electromagnetic fields of the beams calculated using a realistic 3-dimensional field solver. Second, the beams are evolving in the fully self-consistent strong-strong sense where finite particle fluctuation noise is greatly reduced as opposed to the weak-strong models where one beam is fixed.

  20. Three dimensional δf simulations of beams in the SSC

    International Nuclear Information System (INIS)

    Koga, J.; Tajima, T.

    1993-02-01

    A three dimensional δf strong-strong algorithm has been developed to apply to the study of such effects as space charge and beam-beam interaction phenomena in the Superconducting Super Collider (SSC). The algorithm is obtained from the merging of the particle tracking code Simpsons used for 3-dimensional space charge effects and a δf code. The δf method is used to follow the evolution of the non-gaussian part of the beam distribution. The advantages of this method are twofold. First, the Simpsons code utilizes a realistic accelerator model including synchrotron oscillations and energy ramping in 6-dimensional phase space with electromagnetic fields of the beams calculated using a realistic 3-dimensional field solver. Second, the beams are evolving in the fully self-consistent strong-strong sense where finite particle fluctuation noise is greatly reduced as opposed to the weak-strong models where one beam is fixed

  1. Quantum tunneling from three-dimensional black holes

    International Nuclear Information System (INIS)

    Ejaz, Asiya; Gohar, H.; Lin, Hai; Saifullah, K.; Yau, Shing-Tung

    2013-01-01

    We study Hawking radiation from three-dimensional black holes. For this purpose the emission of charged scalar and charged fermionic particles is investigated from charged BTZ black holes, with and without rotation. We use the quantum tunneling approach incorporating WKB approximation and spacetime symmetries. Another class of black holes which is asymptotic to a Sol three-manifold has also been investigated. This procedure gives us the tunneling probability of outgoing particles, and we compute the temperature of the radiation for these black holes. We also consider the quantum tunneling of particles from black hole asymptotic to Sol geometry

  2. The model of the relativistic particle with torsion

    International Nuclear Information System (INIS)

    Plyushchay, M.S.

    1991-01-01

    The model of the relativistic particle with torsion, whose action appears in the Bose-Fermi transmutation mechanism, is canonically quantized in the Minkowski and euclidean spaces. In the Minkowski space there are massive, massless and tachyonic states in the spectrum of the model. In the massive sector the spectrum contains an infinite number of states, whose spin can take integer, half-integer, or fractional values. In the euclidean space, the spectrum is finite and the spin can only be integer, or half-integer. The reasons for the differences of the quantum theory of the model in the two spaces are elucidated. (orig.)

  3. Increased Paracrine Immunomodulatory Potential of Mesenchymal Stromal Cells in Three-Dimensional Culture

    DEFF Research Database (Denmark)

    Follin, Bjarke; Juhl, Morten; Cohen, Smadar

    2016-01-01

    Mesenchymal stromal/stem cells (MSCs) have been investigated extensively through the past years, proving to have great clinical therapeutic potential. In vitro cultivation of MSCs in three-dimensional (3D) culture systems, such as scaffolds, hydrogels, or spheroids, have recently gained attention...... for tissue engineering applications. Studies on MSC spheroids demonstrated that such cultivation increased the paracrine immunomodulatory potential of the MSCs, accompanied by phenotypic alterations. In this review, we gather results from recent experimental studies on the immunomodulatory abilities of MSCs...... when cultured as spheroids or in biomaterials like scaffolds or hydrogels compared to regular two-dimensional (2D) culture and show that alterations occurring to MSCs in spheroids also occur in MSCs in biomaterials. We provide a brief description of known mechanisms of MSC immunomodulatory capacity...

  4. Optical Fiber/Nanowire Hybrid Structures for Efficient Three-Dimensional Dye-Sensitized Solar Cells

    KAUST Repository

    Weintraub, Benjamin

    2009-11-09

    Wired up: The energy conversion efficiency of three-dimensional dye-sensitized solar cells (DSSCs) in a hybrid structure that integrates optical fibers and nanowire arrays is greater than that of a two-dimensional device. Internal axial illumination enhances the energy conversion efficiency of a rectangular fiber-based hybrid structure (see picture) by a factor of up to six compared to light illumination normal to the fiber axis from outside the device.

  5. Cosmology as relativistic particle mechanics: from big crunch to big bang

    Energy Technology Data Exchange (ETDEWEB)

    Russo, J G [Institucio Catalana de Recerca i Estudis Avancats, Departament ECM, Facultat de FIsica, Universitat de Barcelona, Diagonal 647, E-08028 Barcelona (Spain); Townsend, P K [Institucio Catalana de Recerca i Estudis Avancats, Departament ECM, Facultat de FIsica, Universitat de Barcelona, Diagonal 647, E-08028 Barcelona (Spain)

    2005-02-21

    Cosmology can be viewed as geodesic motion in an appropriate metric on an 'augmented' target space; here we obtain these geodesics from an effective relativistic particle action. As an application, we find some exact (flat and curved) cosmologies for models with N scalar fields taking values in a hyperbolic target space for which the augmented target space is a Milne universe. The singularities of these cosmologies correspond to points at which the particle trajectory crosses the Milne horizon, suggesting a novel resolution of them, which we explore via the Wheeler-DeWitt equation.

  6. Relativistic quantum mechanics; Mecanique quantique relativiste

    Energy Technology Data Exchange (ETDEWEB)

    Ollitrault, J.Y. [CEA Saclay, 91 - Gif-sur-Yvette (France). Service de Physique Theorique]|[Universite Pierre et Marie Curie, 75 - Paris (France)

    1998-12-01

    These notes form an introduction to relativistic quantum mechanics. The mathematical formalism has been reduced to the minimum in order to enable the reader to calculate elementary physical processes. The second quantification and the field theory are the logical followings of this course. The reader is expected to know analytical mechanics (Lagrangian and Hamiltonian), non-relativistic quantum mechanics and some basis of restricted relativity. The purpose of the first 3 chapters is to define the quantum mechanics framework for already known notions about rotation transformations, wave propagation and restricted theory of relativity. The next 3 chapters are devoted to the application of relativistic quantum mechanics to a particle with 0,1/5 and 1 spin value. The last chapter deals with the processes involving several particles, these processes require field theory framework to be thoroughly described. (A.C.) 2 refs.

  7. Three-dimensional simulation of super-radiant Smith-Purcell radiation

    International Nuclear Information System (INIS)

    Li, D.; Imasaki, K.; Yang, Z.; Park, Gun-Sik

    2006-01-01

    A simulation of coherent and super-radiant Smith-Purcell radiation is performed in the gigahertz regime using a three-dimensional particle-in-cell code. The simulation model supposes a rectangular grating to be driven by a single electron bunch and a train of periodic bunches, respectively. The true Smith-Purcell radiation is distinguished from the evanescent wave, which has an angle independent frequency lower than the minimum allowed Smith-Purcell frequency. We also find that the super-radiant radiations excited by periodic bunches are emitted at higher harmonics of the bunching frequency and at the corresponding Smith-Purcell angles

  8. Three-Dimensional Organization of Chromosome Territories and the Human Interphase Cell Nucleus

    NARCIS (Netherlands)

    T.A. Knoch (Tobias); C. Münkel (Christian); J. Langowski (Jörg)

    1998-01-01

    textabstractTo study the three-dimensional organization of chromosome territories and the human interphase cell nucleus we developed models which could be compared to experiments. Despite the successful linear sequencing of the human genome its 3D-organization is widely unknown. Using Monte

  9. Alginate foam-based three-dimensional culture to investigate drug sensitivity in primary leukaemia cells.

    Science.gov (United States)

    Karimpoor, Mahroo; Yebra-Fernandez, Eva; Parhizkar, Maryam; Orlu, Mine; Craig, Duncan; Khorashad, Jamshid S; Edirisinghe, Mohan

    2018-04-01

    The development of assays for evaluating the sensitivity of leukaemia cells to anti-cancer agents is becoming an important aspect of personalized medicine. Conventional cell cultures lack the three-dimensional (3D) structure of the bone marrow (BM), the extracellular matrix and stromal components which are crucial for the growth and survival of leukaemia stem cells. To accurately predict the sensitivity of the leukaemia cells in an in vitro assay a culturing system containing the essential components of BM is required. In this study, we developed a porous calcium alginate foam-based scaffold to be used for 3D culture. The new 3D culture was shown to be cell compatible as it supported the proliferation of both normal haematopoietic and leukaemia cells. Our cell differential assay for myeloid markers showed that the porous foam-based 3D culture enhanced myeloid differentiation in both leukaemia and normal haematopoietic cells compared to two-dimensional culture. The foam-based scaffold reduced the sensitivity of the leukaemia cells to the tested antileukaemia agents in K562 and HL60 leukaemia cell line model and also primary myeloid leukaemia cells. This observation supports the application of calcium alginate foams as scaffold components of the 3D cultures for investigation of sensitivity to antileukaemia agents in primary myeloid cells. © 2018 The Author(s).

  10. The efficacy of cetuximab in a tissue-engineered three-dimensional in vitro model of colorectal cancer

    Directory of Open Access Journals (Sweden)

    Tarig Magdeldin

    2014-07-01

    Full Text Available The preclinical development process of chemotherapeutic drugs is often carried out in two-dimensional monolayer cultures. However, a considerable amount of evidence demonstrates that two-dimensional cell culture does not accurately reflect the three-dimensional in vivo tumour microenvironment, specifically with regard to gene expression profiles, oxygen and nutrient gradients and pharmacokinetics. With this objective in mind, we have developed and established a physiologically relevant three-dimensional in vitro model of colorectal cancer based on the removal of interstitial fluid from collagen type I hydrogels. We employed the RAFT™ (Real Architecture For 3D Tissue system for producing three-dimensional cultures to create a controlled reproducible, multiwell testing platform. Using the HT29 and HCT116 cell lines to model epidermal growth factor receptor expressing colorectal cancers, we characterized three-dimensional cell growth and morphology in addition to the anti-proliferative effects of the anti–epidermal growth factor receptor chemotherapeutic agent cetuximab in comparison to two-dimensional monolayer cultures. Cells proliferated well for 14 days in three-dimensional culture and formed well-defined cellular aggregates within the concentrated collagen matrix. Epidermal growth factor receptor expression levels revealed a twofold and threefold increase in three-dimensional cultures for both HT29 and HCT116 cells in comparison to two-dimensional monolayers, respectively (p < 0.05; p < 0.01. Cetuximab efficacy was significantly lower in HT29 three-dimensional cultures in comparison to two-dimensional monolayers, whereas HCT116 cells in both two-dimension and three-dimension were non-responsive to treatment in agreement with their KRAS mutant status. In summary, these results confirm the use of a three-dimensional in vitro cancer model as a suitable drug-screening platform for in vitro pharmacological testing.

  11. A cell-based biosensor for nanomaterials cytotoxicity assessment in three dimensional cell culture

    International Nuclear Information System (INIS)

    Dubiak-Szepietowska, Monika; Karczmarczyk, Aleksandra; Winckler, Thomas; Feller, Karl-Heinz

    2016-01-01

    Nanoparticles (NPs) are widely used in consumer and medicinal products. The high prevalence of nanoparticles in the environment raises concerns regarding their effects on human health, but there is limited knowledge about how NPs interact with cells or tissues. Because the European Union has called for a substantial reduction of animal experiments for scientific purposes (Directive 2010/63), increased efforts are required to develop in vitro models to evaluate potentially hazardous agents. Here, we describe a new cell-based biosensor for the evaluation of NPs cytotoxicity. The new biosensor is based on transgenic human hepatoblastoma cells (HepG2) that express a secreted form of alkaline phosphatase (SEAP) as a reporter protein whose expression is induced upon activation of a stress response pathway controlled by the transcription regulator nuclear factor-κB (NF-κB). The NF-κB-HepG2 sensor cells were cultured in a Matrigel-based three dimensional environment to simulate the in vivo situation. The new biosensor cells offer the advantage of generating fast and reproducible readout at lower concentrations and shorter incubation time than conventional viability assays, avoid possible interaction between nanomaterials and assay compounds, therefore, minimize generation of false positive or negative results and indicate mechanism of toxicity through NF-κB signaling.

  12. Cell origami: self-folding of three-dimensional cell-laden microstructures driven by cell traction force.

    Directory of Open Access Journals (Sweden)

    Kaori Kuribayashi-Shigetomi

    Full Text Available This paper describes a method of generating three-dimensional (3D cell-laden microstructures by applying the principle of origami folding technique and cell traction force (CTF. We harness the CTF as a biological driving force to fold the microstructures. Cells stretch and adhere across multiple microplates. Upon detaching the microplates from a substrate, CTF causes the plates to lift and fold according to a prescribed pattern. This self-folding technique using cells is highly biocompatible and does not involve special material requirements for the microplates and hinges to induce folding. We successfully produced various 3D cell-laden microstructures by just changing the geometry of the patterned 2D plates. We also achieved mass-production of the 3D cell-laden microstructures without causing damage to the cells. We believe that our methods will be useful for biotechnology applications that require analysis of cells in 3D configurations and for self-assembly of cell-based micro-medical devices.

  13. Cell origami: self-folding of three-dimensional cell-laden microstructures driven by cell traction force.

    Science.gov (United States)

    Kuribayashi-Shigetomi, Kaori; Onoe, Hiroaki; Takeuchi, Shoji

    2012-01-01

    This paper describes a method of generating three-dimensional (3D) cell-laden microstructures by applying the principle of origami folding technique and cell traction force (CTF). We harness the CTF as a biological driving force to fold the microstructures. Cells stretch and adhere across multiple microplates. Upon detaching the microplates from a substrate, CTF causes the plates to lift and fold according to a prescribed pattern. This self-folding technique using cells is highly biocompatible and does not involve special material requirements for the microplates and hinges to induce folding. We successfully produced various 3D cell-laden microstructures by just changing the geometry of the patterned 2D plates. We also achieved mass-production of the 3D cell-laden microstructures without causing damage to the cells. We believe that our methods will be useful for biotechnology applications that require analysis of cells in 3D configurations and for self-assembly of cell-based micro-medical devices.

  14. Spontaneous photon emission from a non-relativistic free charged particle in collapse models: A case study

    International Nuclear Information System (INIS)

    Bassi, A.; Donadi, S.

    2014-01-01

    We study the photon emission rate of a non-relativistic charged particle interacting with an external classical noise through its position. Both the particle and the electromagnetic field are quantized. Under only the dipole approximation, the equations of motion can be solved exactly for a free particle, or a particle bounded by an harmonic potential. The physical quantity we will be interested in is the spectrum of the radiation emitted by the particle, due to the interaction with the noise. We will highlight several properties of the spectrum and clarify some issues appearing in the literature, regarding the exact mathematical formula of a spectrum for a free particle.

  15. On the H particle stability in the non relativistic quark model

    International Nuclear Information System (INIS)

    Silvestre-Brac, B.; Carbonell, J.; Gignoux, C.

    1987-05-01

    The H particle with quark content (uuddss) is presented as a good candidate to be stable with respect to strong interactions. In the framework of a non relativistic potential model, the binding energy is calculated by a full dynamical approach using a resonating group trial wave function. The center of mass motion and the Pauli principle are correctly treated. Sophisticated baryon wave functions are employed and the equation of motion is solved with six coupled channels including radial excited baryon states. The effect of breaking SU(3) flavour symmetry is discussed in detail

  16. Generation of a Three-Dimensional Kidney Structure from Pluripotent Stem Cells.

    Science.gov (United States)

    Yoshimura, Yasuhiro; Taguchi, Atsuhiro; Nishinakamura, Ryuichi

    2017-01-01

    The kidney is a vital organ that has an important role in the maintenance of homeostasis by fluid volume regulation and waste product excretion. This role cannot be performed without the three-dimensional (3D) structure of the kidney. Therefore, it is important to generate the 3D structure of the kidney when inducing functional kidney tissue or the whole organ from pluripotent stem cells. In this chapter, we describe the detailed methods to induce kidney progenitor cells from pluripotent stem cells, which are based on embryological development. We also provide a method to generate 3D kidney tissue with vascularized glomeruli upon transplantation.

  17. Relativistic Shock Acceleration

    International Nuclear Information System (INIS)

    Duffy, P.; Downes, T.P.; Gallant, Y.A.; Kirk, J.G.

    1999-01-01

    In this paper we briefly review the basic theory of shock waves in relativistic hydrodynamics and magneto-hydrodynamics, emphasising some astrophysically interesting cases. We then present an overview of the theory of particle acceleration at such shocks describing the methods used to calculate the spectral indices of energetic particles. Recent results on acceleration at ultra-relativistic shocks are discussed. (author)

  18. On the theory of the relativistic motion of a charged particle in the field of intense electromagnetic radiation

    Energy Technology Data Exchange (ETDEWEB)

    Milant' ev, V. P., E-mail: vmilantiev@sci.pfu.edu.ru; Castillo, A. J., E-mail: vmilant@mail.ru [Peoples' Friendship University of Russia (Russian Federation)

    2013-04-15

    Averaged relativistic equations of motion of a charged particle in the field of intense electromagnetic radiation have been obtained in the geometrical optics approximation using the Bogoliubov method. Constraints are determined under which these equations are valid. Oscillating additions to the smoothed dynamical variables of the particle have been found; they are reduced to known expressions in the case of the circularly and linearly polarized plane waves. It has been shown that the expressions for the averaged relativistic force in both cases contain new additional small terms weakening its action. The known difference between the expressions for the ponderomotive force in the cases of circularly and linearly polarized waves has been confirmed.

  19. Relativistic wave mechanics

    CERN Document Server

    Corinaldesi, Ernesto

    1963-01-01

    Geared toward advanced undergraduate and graduate students of physics, this text provides readers with a background in relativistic wave mechanics and prepares them for the study of field theory. The treatment originated as a series of lectures from a course on advanced quantum mechanics that has been further amplified by student contributions.An introductory section related to particles and wave functions precedes the three-part treatment. An examination of particles of spin zero follows, addressing wave equation, Lagrangian formalism, physical quantities as mean values, translation and rotat

  20. [Advances in the research of application of hydrogels in three-dimensional bioprinting].

    Science.gov (United States)

    Yang, J; Zhao, Y; Li, H H; Zhu, S H

    2016-08-20

    Hydrogels are three-dimensional networks made of hydrophilic polymer crosslinked through covalent bonds or physical intermolecular attractions, which can contain growth media and growth factors to support cell growth. In bioprinting, hydrogels are used to provide accurate control over cellular microenvironment and to dramatically reduce experimental repetition times, meanwhile we can obtain three-dimensional cell images of high quality. Hydrogels in three-dimensional bioprinting have received a considerable interest due to their structural similarities to the natural extracellular matrix and polyporous frameworks which can support the cellular proliferation and survival. Meanwhile, they are accompanied by many challenges.

  1. A relativistic, meson exchange model of pion-nucleon scattering

    International Nuclear Information System (INIS)

    Pearces, B.C.; Jennings, B.K.

    1990-06-01

    A relativistic meson exchange approach to the pion-nucleon interaction is developed using a three-dimensional relativistic two-body propagator, and the results using different propagators are compared. The relativistic approach is able to describe low energy scattering up to 400 MeV above threshold, while preserving the soft pion theorems. The different propagators give similar results, as the form factors necessary to get a fit suppress much of the multiple scattering. (Author) (24 refs., 4 tabs., 6 figs.)

  2. Fabrication of cell-benign inverse opal hydrogels for three-dimensional cell culture.

    Science.gov (United States)

    Im, Pilseon; Ji, Dong Hwan; Kim, Min Kyung; Kim, Jaeyun

    2017-05-15

    Inverse opal hydrogels (IOHs) for cell culture were fabricated and optimized using calcium-crosslinked alginate microbeads as sacrificial template and gelatin as a matrix. In contrast to traditional three-dimensional (3D) scaffolds, the gelatin IOHs allowed the utilization of both the macropore surface and inner matrix for cell co-culture. In order to remove templates efficiently for the construction of 3D interconnected macropores and to maintain high cell viability during the template removal process using EDTA solution, various factors in fabrication, including alginate viscosity, alginate concentration, alginate microbeads size, crosslinking calcium concentration, and gelatin network density were investigated. Low viscosity alginate, lower crosslinking calcium ion concentration, and lower concentration of alginate and gelatin were found to obtain high viability of cells encapsulated in the gelatin matrix after removal of the alginate template by EDTA treatment by allowing rapid dissociation and diffusion of alginate polymers. Based on the optimized fabrication conditions, gelatin IOHs showed good potential as a cell co-culture system, applicable to tissue engineering and cancer research. Copyright © 2017 Elsevier Inc. All rights reserved.

  3. particle simulation for electrostatic oscillation of virtual cathode in relativistic electron beams

    International Nuclear Information System (INIS)

    Chen Deming; Wang Min

    1990-01-01

    The virtual cathode oscillation in relativistic electron beams is studied by a 1-D electrostatic particle simulation code with finite-size-particle model. When injection current is less than the space charge limiting current, electron beam propagates stably and transsmits completely. When injection current exceeds the space charge limit, its propagation is unstable, a part of electrons reflect and the other electrons transsmit. The position and potential of the virtual cathode caused by space charge effects oscillate periodically. When the beam current increases, the virtual cathode position closer to the injection plane and its oscillating region gets narrower, the virtual cathode potential decreases and its amplitude increases, the oscillation frequency increases above the beam plasma frequency

  4. Relativistic quantum mechanics and introduction to field theory

    Energy Technology Data Exchange (ETDEWEB)

    Yndurain, F.J. [Universidad Autonoma de Madrid (Spain). Dept. de Fisica Teorica

    1996-12-01

    The following topics were dealt with: relativistic transformations, the Lorentz group, Klein-Gordon equation, spinless particles, spin 1/2 particles, Dirac particle in a potential, massive spin 1 particles, massless spin 1 particles, relativistic collisions, S matrix, cross sections, decay rates, partial wave analysis, electromagnetic field quantization, interaction of radiation with matter, interactions in quantum field theory and relativistic interactions with classical sources.

  5. Relativistic quantum mechanics and introduction to field theory

    International Nuclear Information System (INIS)

    Yndurain, F.J.

    1996-01-01

    The following topics were dealt with: relativistic transformations, the Lorentz group, Klein-Gordon equation, spinless particles, spin 1/2 particles, Dirac particle in a potential, massive spin 1 particles, massless spin 1 particles, relativistic collisions, S matrix, cross sections, decay rates, partial wave analysis, electromagnetic field quantization, interaction of radiation with matter, interactions in quantum field theory and relativistic interactions with classical sources

  6. Numerical investigation of kinetic turbulence in relativistic pair plasmas - I. Turbulence statistics

    Science.gov (United States)

    Zhdankin, Vladimir; Uzdensky, Dmitri A.; Werner, Gregory R.; Begelman, Mitchell C.

    2018-02-01

    We describe results from particle-in-cell simulations of driven turbulence in collisionless, magnetized, relativistic pair plasma. This physical regime provides a simple setting for investigating the basic properties of kinetic turbulence and is relevant for high-energy astrophysical systems such as pulsar wind nebulae and astrophysical jets. In this paper, we investigate the statistics of turbulent fluctuations in simulations on lattices of up to 10243 cells and containing up to 2 × 1011 particles. Due to the absence of a cooling mechanism in our simulations, turbulent energy dissipation reduces the magnetization parameter to order unity within a few dynamical times, causing turbulent motions to become sub-relativistic. In the developed stage, our results agree with predictions from magnetohydrodynamic turbulence phenomenology at inertial-range scales, including a power-law magnetic energy spectrum with index near -5/3, scale-dependent anisotropy of fluctuations described by critical balance, lognormal distributions for particle density and internal energy density (related by a 4/3 adiabatic index, as predicted for an ultra-relativistic ideal gas), and the presence of intermittency. We also present possible signatures of a kinetic cascade by measuring power-law spectra for the magnetic, electric and density fluctuations at sub-Larmor scales.

  7. Three-dimensional ultrastructural analyses of anterior pituitary gland expose spatial relationships between endocrine cell secretory granule localization and capillary distribution.

    Science.gov (United States)

    Yoshitomi, Munetake; Ohta, Keisuke; Kanazawa, Tomonoshin; Togo, Akinobu; Hirashima, Shingo; Uemura, Kei-Ichiro; Okayama, Satoko; Morioka, Motohiro; Nakamura, Kei-Ichiro

    2016-10-31

    Endocrine and endothelial cells of the anterior pituitary gland frequently make close appositions or contacts, and the secretory granules of each endocrine cell tend to accumulate at the perivascular regions, which is generally considered to facilitate secretory functions of these cells. However, three-dimensional relationships between the localization pattern of secretory granules and blood vessels are not fully understood. To define and characterize these spatial relationships, we used scanning electron microscopy (SEM) three-dimensional reconstruction method based on focused ion-beam slicing and scanning electron microscopy (FIB/SEM). Full three-dimensional cellular architectures of the anterior pituitary tissue at ultrastructural resolution revealed that about 70% of endocrine cells were in apposition to the endothelial cells, while almost 30% of endocrine cells were entirely isolated from perivascular space in the tissue. Our three-dimensional analyses also visualized the distribution pattern of secretory granules in individual endocrine cells, showing an accumulation of secretory granules in regions in close apposition to the blood vessels in many cases. However, secretory granules in cells isolated from the perivascular region tended to distribute uniformly in the cytoplasm of these cells. These data suggest that the cellular interactions between the endocrine and endothelial cells promote an uneven cytoplasmic distribution of the secretory granules.

  8. Exact solution of the relativistic Coulomb problem for two-particle bound states in the quasipotential approach

    International Nuclear Information System (INIS)

    Kapshay, V.N.; Skachkov, N.B.

    1979-01-01

    A composite system of two relativistic particles is studied on the basis of the Kadyshevsky quasipotential equation, in which the ''Coulomb'' potential is taken in the form of a propagator of the massless-scalar-particle exchange. The obtained exact solutions to this equation are shown to be a geometrical generalization of nonrelativistic Coulomb wave functions in the sense of change of the Euclidean geometry of momentum space to the Lobachevsky geometry

  9. Particle-in-Cell Codes for plasma-based particle acceleration

    CERN Document Server

    Pukhov, Alexander

    2016-01-01

    Basic principles of particle-in-cell (PIC ) codes with the main application for plasma-based acceleration are discussed. The ab initio full electromagnetic relativistic PIC codes provide the most reliable description of plasmas. Their properties are considered in detail. Representing the most fundamental model, the full PIC codes are computationally expensive. The plasma-based acceler- ation is a multi-scale problem with very disparate scales. The smallest scale is the laser or plasma wavelength (from one to hundred microns) and the largest scale is the acceleration distance (from a few centimeters to meters or even kilometers). The Lorentz-boost technique allows to reduce the scale disparity at the costs of complicating the simulations and causing unphysical numerical instabilities in the code. Another possibility is to use the quasi-static approxi- mation where the disparate scales are separated analytically.

  10. Three-Dimensional Printing and Cell Therapy for Wound Repair.

    Science.gov (United States)

    van Kogelenberg, Sylvia; Yue, Zhilian; Dinoro, Jeremy N; Baker, Christopher S; Wallace, Gordon G

    2018-05-01

    Significance: Skin tissue damage is a major challenge and a burden on healthcare systems, from burns and other trauma to diabetes and vascular disease. Although the biological complexities are relatively well understood, appropriate repair mechanisms are scarce. Three-dimensional bioprinting is a layer-based approach to regenerative medicine, whereby cells and cell-based materials can be dispensed in fine spatial arrangements to mimic native tissue. Recent Advances: Various bioprinting techniques have been employed in wound repair-based skin tissue engineering, from laser-induced forward transfer to extrusion-based methods, and with the investigation of the benefits and shortcomings of each, with emphasis on biological compatibility and cell proliferation, migration, and vitality. Critical issues: Development of appropriate biological inks and the vascularization of newly developed tissues remain a challenge within the field of skin tissue engineering. Future Directions: Progress within bioprinting requires close interactions between material scientists, tissue engineers, and clinicians. Microvascularization, integration of multiple cell types, and skin appendages will be essential for creation of complex skin tissue constructs.

  11. Elementary particle theory

    CERN Document Server

    Stefanovich, Eugene

    2018-01-01

    This book introduces notation, terminology, and basic ideas of relativistic quantum theories. The discussion proceeds systematically from the principle of relativity and postulates of quantum logics to the construction of Poincaré invariant few-particle models of interaction and scattering. It is the first of three volumes formulating a consistent relativistic quantum theory of interacting charged particles.

  12. Three dimensional illustrating - three-dimensional vision and deception of sensibility

    Directory of Open Access Journals (Sweden)

    Anita Gánóczy

    2009-03-01

    Full Text Available The wide-spread digital photography and computer use gave the opportunity for everyone to make three-dimensional pictures and to make them public. The new opportunities with three-dimensional techniques give chance for the birth of new artistic photographs. We present in detail the biological roots of three-dimensional visualization, the phenomena of movement parallax, which can be used efficiently in making three-dimensional graphics, the Zöllner- and Corridor-illusion. There are present in this paper the visual elements, which contribute to define a plane two-dimensional image in three-dimension: coherent lines, the covering, the measurement changes, the relative altitude state, the abatement of detail profusion, the shadings and the perspective effects of colors.

  13. Development of human nervous tissue upon differentiation of embryonic stem cells in three-dimensional culture.

    Science.gov (United States)

    Preynat-Seauve, Olivier; Suter, David M; Tirefort, Diderik; Turchi, Laurent; Virolle, Thierry; Chneiweiss, Herve; Foti, Michelangelo; Lobrinus, Johannes-Alexander; Stoppini, Luc; Feki, Anis; Dubois-Dauphin, Michel; Krause, Karl Heinz

    2009-03-01

    Researches on neural differentiation using embryonic stem cells (ESC) require analysis of neurogenesis in conditions mimicking physiological cellular interactions as closely as possible. In this study, we report an air-liquid interface-based culture of human ESC. This culture system allows three-dimensional cell expansion and neural differentiation in the absence of added growth factors. Over a 3-month period, a macroscopically visible, compact tissue developed. Histological coloration revealed a dense neural-like neural tissue including immature tubular structures. Electron microscopy, immunochemistry, and electrophysiological recordings demonstrated a dense network of neurons, astrocytes, and oligodendrocytes able to propagate signals. Within this tissue, tubular structures were niches of cells resembling germinal layers of human fetal brain. Indeed, the tissue contained abundant proliferating cells expressing markers of neural progenitors. Finally, the capacity to generate neural tissues on air-liquid interface differed for different ESC lines, confirming variations of their neurogenic potential. In conclusion, this study demonstrates in vitro engineering of a human neural-like tissue with an organization that bears resemblance to early developing brain. As opposed to previously described methods, this differentiation (a) allows three-dimensional organization, (b) yields dense interconnected neural tissue with structurally and functionally distinct areas, and (c) is spontaneously guided by endogenous developmental cues.

  14. Dependence of the quasipotential on the total energy of a two-particle system

    International Nuclear Information System (INIS)

    Kapshai, V.N.; Savrin, V.I.; Skachkov, N.B.

    1987-01-01

    For a system of two relativistic particles described in the Logunov-Tavkhelidze one-time approach the dependence of the quasipotential of one-boson exchange on the total energy of the system is calculated. It is shown that despite the nonlocal form of the obtained quasipotential the three-dimensional equations for the waves function can be reduced by a partial expansion to one-dimensional equations. The influence of the energy dependence of the quasipotential on its behavior in the coordinate representation is discussed

  15. Post-arc current simulation based on measurement in vacuum circuit breaker with a one-dimensional particle-in-cell model

    Science.gov (United States)

    Jia, Shenli; Mo, Yongpeng; Shi, Zongqian; Li, Junliang; Wang, Lijun

    2017-10-01

    The post-arc dielectric recovery process has a decisive effect on the current interruption performance in a vacuum circuit breaker. The dissipation of residual plasma at the moment of current zero under the transient recovery voltage, which is the first stage of the post-arc dielectric recovery process and forms the post-arc current, has attracted many concerns. A one-dimensional particle-in-cell model is developed to simulate the measured post-arc current in the vacuum circuit breaker in this paper. At first, the parameters of the residual plasma are estimated roughly by the waveform of the post-arc current which is taken from measurements. After that, different components of the post-arc current, which are formed by the movement of charged particles in the residual plasma, are discussed. Then, the residual plasma density is adjusted according to the proportion of electrons and ions absorbed by the post-arc anode derived from the particle-in-cell simulation. After this adjustment, the post-arc current waveform obtained from the simulation is closer to that obtained from measurements.

  16. Synchronous motion of a relativistic particles in the wave propagating at the angle to a magnetic field

    International Nuclear Information System (INIS)

    Milant'ev, V.P.

    1996-01-01

    It is shown that within the transverse or the longitudinal wave propagating at the angle to the magnetic field there is a specific mode of motion of relativistic particle called as a synchronous one where the condition of a particle resonance with the wave is realized with increasing accuracy with increase of particle energy. A trend to the unlimited acceleration is detected in a synchronous mode of the Cherenkov resonance. 21 refs

  17. Apar-T: code, validation, and physical interpretation of particle-in-cell results

    Science.gov (United States)

    Melzani, Mickaël; Winisdoerffer, Christophe; Walder, Rolf; Folini, Doris; Favre, Jean M.; Krastanov, Stefan; Messmer, Peter

    2013-10-01

    We present the parallel particle-in-cell (PIC) code Apar-T and, more importantly, address the fundamental question of the relations between the PIC model, the Vlasov-Maxwell theory, and real plasmas. First, we present four validation tests: spectra from simulations of thermal plasmas, linear growth rates of the relativistic tearing instability and of the filamentation instability, and nonlinear filamentation merging phase. For the filamentation instability we show that the effective growth rates measured on the total energy can differ by more than 50% from the linear cold predictions and from the fastest modes of the simulation. We link these discrepancies to the superparticle number per cell and to the level of field fluctuations. Second, we detail a new method for initial loading of Maxwell-Jüttner particle distributions with relativistic bulk velocity and relativistic temperature, and explain why the traditional method with individual particle boosting fails. The formulation of the relativistic Harris equilibrium is generalized to arbitrary temperature and mass ratios. Both are required for the tearing instability setup. Third, we turn to the key point of this paper and scrutinize the question of what description of (weakly coupled) physical plasmas is obtained by PIC models. These models rely on two building blocks: coarse-graining, i.e., grouping of the order of p ~ 1010 real particles into a single computer superparticle, and field storage on a grid with its subsequent finite superparticle size. We introduce the notion of coarse-graining dependent quantities, i.e., quantities depending on p. They derive from the PIC plasma parameter ΛPIC, which we show to behave as ΛPIC ∝ 1/p. We explore two important implications. One is that PIC collision- and fluctuation-induced thermalization times are expected to scale with the number of superparticles per grid cell, and thus to be a factor p ~ 1010 smaller than in real plasmas, a fact that we confirm with

  18. Framework to model neutral particle flux in convex high aspect ratio structures using one-dimensional radiosity

    Science.gov (United States)

    Manstetten, Paul; Filipovic, Lado; Hössinger, Andreas; Weinbub, Josef; Selberherr, Siegfried

    2017-02-01

    We present a computationally efficient framework to compute the neutral flux in high aspect ratio structures during three-dimensional plasma etching simulations. The framework is based on a one-dimensional radiosity approach and is applicable to simulations of convex rotationally symmetric holes and convex symmetric trenches with a constant cross-section. The framework is intended to replace the full three-dimensional simulation step required to calculate the neutral flux during plasma etching simulations. Especially for high aspect ratio structures, the computational effort, required to perform the full three-dimensional simulation of the neutral flux at the desired spatial resolution, conflicts with practical simulation time constraints. Our results are in agreement with those obtained by three-dimensional Monte Carlo based ray tracing simulations for various aspect ratios and convex geometries. With this framework we present a comprehensive analysis of the influence of the geometrical properties of high aspect ratio structures as well as of the particle sticking probability on the neutral particle flux.

  19. Investigating the Role of Surface Materials and Three Dimensional Architecture on In Vitro Differentiation of Porcine Monocyte-Derived Dendritic Cells

    DEFF Research Database (Denmark)

    Hartmann, Sofie Bruun; Mohanty, Soumyaranjan; Skovgaard, Kerstin

    2016-01-01

    In vitro generation of dendritic-like cells through differentiation of peripheral blood monocytes is typically done using two-dimensional polystyrene culture plates. In the process of optimising cell culture techniques, engineers have developed fluidic micro-devises usually manufactured in materi......In vitro generation of dendritic-like cells through differentiation of peripheral blood monocytes is typically done using two-dimensional polystyrene culture plates. In the process of optimising cell culture techniques, engineers have developed fluidic micro-devises usually manufactured......-dimensional PDMS and carbonised three-dimensional PDMS. Cells cultured conventionally (on two-dimensional polystyrene) differentiated into moDCs as expected. Interestingly, gene expression of a wide range of cytokines, chemokines, and pattern recognition receptors was influenced by culture surface material...... and IL23A) but the influence of the surfaces was unchanged. These findings highlights future challenges of combining and comparing data generated from microfluidic cell culture-devices made using alternative materials to data generated using conventional polystyrene plates used by most laboratories today....

  20. Confinement limit of a Dirac particle in two and three dimensions

    International Nuclear Information System (INIS)

    Toyama, F.M.; Nogami, Y.

    2010-01-01

    Consider a particle that is in a stationary state described by the Dirac equation with a finite-range potential. In two and three dimensions the particle can be confined to an arbitrarily small spatial region. This is in contrast to the one-dimensional case in which the confinement region cannot be much narrower than the Compton wavelength.

  1. Three-dimensional printing of Hela cells for cervical tumor model in vitro

    International Nuclear Information System (INIS)

    Zhao, Yu; Yao, Rui; Ouyang, Liliang; Ding, Hongxu; Zhang, Ting; Sun, Wei; Zhang, Kaitai; Cheng, Shujun

    2014-01-01

    Advances in three-dimensional (3D) printing have enabled the direct assembly of cells and extracellular matrix materials to form in vitro cellular models for 3D biology, the study of disease pathogenesis and new drug discovery. In this study, we report a method of 3D printing for Hela cells and gelatin/alginate/fibrinogen hydrogels to construct in vitro cervical tumor models. Cell proliferation, matrix metalloproteinase (MMP) protein expression and chemoresistance were measured in the printed 3D cervical tumor models and compared with conventional 2D planar culture models. Over 90% cell viability was observed using the defined printing process. Comparisons of 3D and 2D results revealed that Hela cells showed a higher proliferation rate in the printed 3D environment and tended to form cellular spheroids, but formed monolayer cell sheets in 2D culture. Hela cells in 3D printed models also showed higher MMP protein expression and higher chemoresistance than those in 2D culture. These new biological characteristics from the printed 3D tumor models in vitro as well as the novel 3D cell printing technology may help the evolution of 3D cancer study. (paper)

  2. Study of the equations of a particle in Non- Relativistic Quantum Mechanics

    International Nuclear Information System (INIS)

    Miltao, Milton Souza Ribeiro; Silva, Vanessa Santos Teles da

    2011-01-01

    Full text: The study of group theory is relevant to the treatment of physical problems, in which concepts of invariance and symmetry are important. In the field of Non-Relativistic Quantum Mechanics, we can do algebraic considerations taking into account the principles of symmetry, considering the framework of the study of Galileo transformations, which have characteristics of group. Therefore, we discuss the Stern-Gerlach experiment that had the historical importance of demonstrating that the electron has an intrinsic angular momentum. Through discussion of this experiment, we found that the spin appears in Non-Relativistic Quantum Mechanics as a feature of the algebraic structure underlying any physical theory represented by a group. From these studies, we have algebraic considerations for physical systems in non-relativistic domain, which are described by the Schroedinger and Pauli equations, describing the dynamics of particles of spin zero and 1/2 respectively, taking into account the structure of the transformations Galileo. Due to the operatorial, we represent Galileo's transformations by matrices by choosing an appropriate basis of space-time. Using these arrays, we saw group characteristics associated with these transformations, which we call the Galileo Group. We note the invariance of the Schroedinger and Pauli equations after these changes, as well as the physical state associated with it, which is represented by a radius vector in Hilbert space. (author)

  3. Relativistic mean field model for entrainment in general relativistic superfluid neutron stars

    International Nuclear Information System (INIS)

    Comer, G.L.; Joynt, R.

    2003-01-01

    General relativistic superfluid neutron stars have a significantly more intricate dynamics than their ordinary fluid counterparts. Superfluidity allows different superfluid (and superconducting) species of particles to have independent fluid flows, a consequence of which is that the fluid equations of motion contain as many fluid element velocities as superfluid species. Whenever the particles of one superfluid interact with those of another, the momentum of each superfluid will be a linear combination of both superfluid velocities. This leads to the so-called entrainment effect whereby the motion of one superfluid will induce a momentum in the other superfluid. We have constructed a fully relativistic model for entrainment between superfluid neutrons and superconducting protons using a relativistic σ-ω mean field model for the nucleons and their interactions. In this context there are two notions of 'relativistic': relativistic motion of the individual nucleons with respect to a local region of the star (i.e. a fluid element containing, say, an Avogadro's number of particles), and the motion of fluid elements with respect to the rest of the star. While it is the case that the fluid elements will typically maintain average speeds at a fraction of that of light, the supranuclear densities in the core of a neutron star can make the nucleons themselves have quite high average speeds within each fluid element. The formalism is applied to the problem of slowly rotating superfluid neutron star configurations, a distinguishing characteristic being that the neutrons can rotate at a rate different from that of the protons

  4. Four-dimensional jets of hadrons: universal characteristics of multiple production of particles

    International Nuclear Information System (INIS)

    Baldin, A.M.; Batyunya, B.V.; Gramenitskii, I.M.; Grishin, V.G.; Didenko, L.A.; Kuznetsov, A.A.; Metreveli, Z.V.

    1986-01-01

    In a new relativistically invariant approach, data on multiple production of particles are analyzed in pp, p-barp, π - p, π - C, pC, and pTa interactions in the momentum range from 6 to 205 GeV/c. Distributions of hadrons (π - , K 0 /sub S/, Λ) in the square of the 4-velocity (b/sub k/) relative to the jet axis are obtained. It is shown that at a momentum p/sub lab/ ≥22 GeV/c these distributions do not depend on energy and are identical for hadronization of quarks and of multiquark systems. The observed universal properties of 4-dimensional jets of hadrons apparently are fundamental characteristics of interactions of color charges with the vacuum

  5. Three-dimensional self-branching anatase TiO{sub 2} nanorods with the improved carrier collection for SrTiO{sub 3}-based perovskite solar cells

    Energy Technology Data Exchange (ETDEWEB)

    Hu, Yajing; Wang, Chen; Tang, Ying; Huang, Lu [Department of Electronic Information Materials, School of Materials Science and Engineering, Shanghai University, Shanghai 200444 (China); Fu, Jianxun [Key Laboratory of Modern Metallurgy and Materials Processing, School of Materials Science and Engineering, Shanghai University, Shanghai 200072 (China); Shi, Weimin; Wang, Linjun [Department of Electronic Information Materials, School of Materials Science and Engineering, Shanghai University, Shanghai 200444 (China); Yang, Weiguang, E-mail: wgyang@shu.edu.cn [Department of Electronic Information Materials, School of Materials Science and Engineering, Shanghai University, Shanghai 200444 (China)

    2016-09-15

    The organic–inorganic perovskite solar cells based on ternary oxide SrTiO{sub 3} shows a higher Voc, attributed to its slightly higher conduction band edge and better morphology of absorber material. However, its less efficient carrier collection and limited overall interfacial areas between the absorber material and the electron-transport layer (ETL), dramatically reducing the Jsc. Here, By adjusting the concentrations of the Ti(OBu){sub 4}, we successfully prepared the three-dimensional (3D) self-branching anatase TiO{sub 2} nanorod/SrTiO{sub 3} nanocomposites, and slightly tuned the particle size of SrTiO{sub 3}. With the incorporation of the three-dimensional (3D) self-branching anatase TiO{sub 2} nanorod, the Jsc of the device based on SrTiO{sub 3} was highly boosted. The best performing solar cell we obtained exhibited a PCE of 9.99% with a Jsc of 19.48 mA/cm{sup 2}. The excellent performance could be ascribed to the improvement of charge carrier collection of SrTiO{sub 3}, better surface coverage and crystallinity of CH{sub 3}NH{sub 3}PbI{sub 3}, and enhanced light scattering ability caused by 3D self-branching anatase TiO{sub 2} nanorods. - Highlights: • The three-dimensional (3D) self-branching anatase TiO{sub 2} nanorod/SrTiO{sub 3} nanocomposites were prepared. • The particle sizes of SrTiO{sub 3} can be slightly tuned. • The best performing solar cell we obtained exhibited a PCE of 9.99% with the Jsc of 19.48 mA/cm{sup 2}.

  6. Geometric influences of a particle confined to a curved surface embedded in three-dimensional Euclidean space

    Science.gov (United States)

    Wang, Yong-Long; Jiang, Hua; Zong, Hong-Shi

    2017-08-01

    In the spirit of the thin-layer quantization approach, we give the formula of the geometric influences of a particle confined to a curved surface embedded in three-dimensional Euclidean space. The geometric contributions can result from the reduced commutation relation between the acted function depending on normal variable and the normal derivative. According to the formula, we obtain the geometric potential, geometric momentum, geometric orbital angular momentum, geometric linear Rashba, and cubic Dresselhaus spin-orbit couplings. As an example, a truncated cone surface is considered. We find that the geometric orbital angular momentum can provide an azimuthal polarization for spin, and the sign of the geometric Dresselhaus spin-orbit coupling can be flipped through the inclination angle of generatrix.

  7. Single-cell printing to form three-dimensional lines of olfactory ensheathing cells

    International Nuclear Information System (INIS)

    Othon, Christina M; Ringeisen, Bradley R; Wu Xingjia; Anders, Juanita J

    2008-01-01

    Biological laser printing (BioLP(TM)) is a unique tool capable of printing high resolution two- and three-dimensional patterns of living mammalian cells, with greater than 95% viability. These results have been extended to primary cultured olfactory ensheathing cells (OECs), harvested from adult Sprague-Dawley rats. OECs have been found to provide stimulating environments for neurite outgrowth in spinal cord injury models. BioLP is unique in that small load volumes (∼μLs) are required to achieve printing, enabling low numbers of OECs to be harvested, concentrated and printed. BioLP was used to form several 8 mm lines of OECs throughout a multilayer hydrogel scaffold. The line width was as low as 20 μm, with most lines comprising aligned single cells. Fluorescent confocal microscopy was used to determine the functionality of the printed OECs, to monitor interactions between printed OECs, and to determine the extent of cell migration throughout the 3D scaffold. High-resolution printing of low cell count, harvested OECs is an important advancement for in vitro study of cell interactions and functionality. In addition, these cell-printed scaffolds may provide an alternative for spinal cord repair studies, as the single-cell patterns formed here are on relevant size scales for neurite outgrowth

  8. Time Operator in Relativistic Quantum Mechanics

    Science.gov (United States)

    Khorasani, Sina

    2017-07-01

    It is first shown that the Dirac’s equation in a relativistic frame could be modified to allow discrete time, in agreement to a recently published upper bound. Next, an exact self-adjoint 4 × 4 relativistic time operator for spin-1/2 particles is found and the time eigenstates for the non-relativistic case are obtained and discussed. Results confirm the quantum mechanical speculation that particles can indeed occupy negative energy levels with vanishingly small but non-zero probablity, contrary to the general expectation from classical physics. Hence, Wolfgang Pauli’s objection regarding the existence of a self-adjoint time operator is fully resolved. It is shown that using the time operator, a bosonic field referred here to as energons may be created, whose number state representations in non-relativistic momentum space can be explicitly found.

  9. All-sky analysis of the general relativistic galaxy power spectrum

    Science.gov (United States)

    Yoo, Jaiyul; Desjacques, Vincent

    2013-07-01

    We perform an all-sky analysis of the general relativistic galaxy power spectrum using the well-developed spherical Fourier decomposition. Spherical Fourier analysis expresses the observed galaxy fluctuation in terms of the spherical harmonics and spherical Bessel functions that are angular and radial eigenfunctions of the Helmholtz equation, providing a natural orthogonal basis for all-sky analysis of the large-scale mode measurements. Accounting for all the relativistic effects in galaxy clustering, we compute the spherical power spectrum and its covariance matrix and compare it to the standard three-dimensional power spectrum to establish a connection. The spherical power spectrum recovers the three-dimensional power spectrum at each wave number k with its angular dependence μk encoded in angular multipole l, and the contributions of the line-of-sight projection to galaxy clustering such as the gravitational lensing effect can be readily accommodated in the spherical Fourier analysis. A complete list of formulas for computing the relativistic spherical galaxy power spectrum is also presented.

  10. Three-dimensional optofluidic device for isolating microbes

    Science.gov (United States)

    Keloth, A.; Paterson, L.; Markx, G. H.; Kar, A. K.

    2015-03-01

    Development of efficient methods for isolation and manipulation of microorganisms is essential to study unidentified and yet-to-be cultured microbes originating from a variety of environments. The discovery of novel microbes and their products have the potential to contribute to the development of new medicines and other industrially important bioactive compounds. In this paper we describe the design, fabrication and validation of an optofluidic device capable of redirecting microbes within a flow using optical forces. The device holds promise to enable the high throughput isolation of single microbes for downstream culture and analysis. Optofluidic devices are widely used in clinical research, cell biology and biomedical engineering as they are capable of performing analytical functions such as controlled transportation, compact and rapid processing of nanolitres to millilitres of clinical or biological samples. We have designed and fabricated a three dimensional optofluidic device to control and manipulate microorganisms within a microfluidic channel. The device was fabricated in fused silica by ultrafast laser inscription (ULI) followed by selective chemical etching. The unique three-dimensional capability of ULI is utilized to integrate microfluidic channels and waveguides within the same substrate. The main microfluidic channel in the device constitutes the path of the sample. Optical waveguides are fabricated at right angles to the main microfluidic channel. The potential of the optical scattering force to control and manipulate microorganisms is discussed in this paper. A 980 nm continuous wave (CW) laser source, coupled to the waveguide, is used to exert radiation pressure on the particle and particle migrations at different flow velocities are recorded. As a first demonstration, device functionality is validated using fluorescent microbeads and initial trials with microalgae are presented.

  11. Beyond the relativistic mean-field approximation. II. Configuration mixing of mean-field wave functions projected on angular momentum and particle number

    International Nuclear Information System (INIS)

    Niksic, T.; Vretenar, D.; Ring, P.

    2006-01-01

    The framework of relativistic self-consistent mean-field models is extended to include correlations related to the restoration of broken symmetries and to fluctuations of collective variables. The generator coordinate method is used to perform configuration mixing of angular-momentum and particle-number projected relativistic wave functions. The geometry is restricted to axially symmetric shapes, and the intrinsic wave functions are generated from the solutions of the relativistic mean-field+Lipkin-Nogami BCS equations, with a constraint on the mass quadrupole moment. The model employs a relativistic point-coupling (contact) nucleon-nucleon effective interaction in the particle-hole channel, and a density-independent δ-interaction in the pairing channel. Illustrative calculations are performed for 24 Mg, 32 S, and 36 Ar, and compared with results obtained employing the model developed in the first part of this work, i.e., without particle-number projection, as well as with the corresponding nonrelativistic models based on Skyrme and Gogny effective interactions

  12. One and two dimensional simulations on beat wave acceleration

    International Nuclear Information System (INIS)

    Mori, W.; Joshi, C.; Dawson, J.M.; Forslund, D.W.; Kindel, J.M.

    1984-01-01

    Recently there has been considerable interest in the use of fast-large-amplitude plasma waves as the basis for a high energy particle accelerator. In these schemes, lasers are used to create the plasma wave. To date the few simulation studies on this subject have been limited to one-dimensional, short rise time simulations. Here the authors present results from simulations in which more realistic parameters are used. In addition, they present the first two dimensional simulations on this subject. One dimensional simulations on a 2 1/2-D relativistic electromagnetic particle code, in which only a few cells were used in one direction, on colinear optical mixing are presented. In these simulations the laser rise time, laser intensity, plasma density, plasma temperature and system size were varied. The simulations indicate that the theory of Rosenbluth and Liu is applicable over a wide range of parameters. In addition, simulations with a DC magnetic field are presented in order to study the ''Surfatron'' concept

  13. Clonorchis sinensis infestation promotes three-dimensional aggregation and invasion of cholangiocarcinoma cells.

    Directory of Open Access Journals (Sweden)

    Jihee Won

    Full Text Available Numerous experimental and epidemiological studies have demonstrated a correlation between Clonorchis sinensis (C. sinensis infestation and cholangiocarcinoma (CCA. However, the role of C. sinensis in the increased invasiveness and proliferation involved in the malignancy of CCA has not been addressed yet. Here, we investigated the possibility that C. sinensis infestation promotes expression of focal and cell-cell adhesion proteins in CCA cells and secretion of matrix metalloproteinases (MMPs. Adhesion proteins help maintain cell aggregates, and MMPs promote the three-dimensional invasion of cells into the neighboring extracellular matrix (ECM. Using a novel microfluidic assay, we quantitatively addressed the role of excretory-secretory products (ESPs gradients from C. sinensis in promoting the invasion of cells into the neighboring ECM.

  14. Bound states and scattering lengths of three two-component particles with zero-range interactions under one-dimensional confinement

    International Nuclear Information System (INIS)

    Kartavtsev, O.I.; Malykh, A.V.; Sofianos, S.A.

    2008-01-01

    The universal three-body dynamics in ultracold binary gases confined to one-dimensional motion is studied. The three-body binding energies and the (2+1)-scattering lengths are calculated for two identical particles of mass m and a different one of mass m 1 , between which interactions are described in the low-energy limit by zero-range potentials. The critical values of the mass ratio m/m 1 , at which the three-body states arise and the (2+1)-scattering length equals zero, are determined both for zero and infinite interaction strength λ 1 of the identical particles. A number of exact results are enlisted and asymptotic dependences both for m/m 1 → infinity and λ 1 → -infinity are derived. Combining the numerical and analytical results, a schematic diagram showing the number of the three-body bound states and the sign of the (2+1)-scattering length in the plane of the mass ratio and interaction-strength ratio is deduced. The results provide a description of the homogeneous and mixed phases of atoms and molecules in dilute binary quantum gases

  15. Laser-pulse compression in a collisional plasma under weak-relativistic ponderomotive nonlinearity

    International Nuclear Information System (INIS)

    Singh, Mamta; Gupta, D. N.

    2016-01-01

    We present theory and numerical analysis which demonstrate laser-pulse compression in a collisional plasma under the weak-relativistic ponderomotive nonlinearity. Plasma equilibrium density is modified due to the ohmic heating of electrons, the collisions, and the weak relativistic-ponderomotive force during the interaction of a laser pulse with plasmas. First, within one-dimensional analysis, the longitudinal self-compression mechanism is discussed. Three-dimensional analysis (spatiotemporal) of laser pulse propagation is also investigated by coupling the self-compression with the self-focusing. In the regime in which the laser becomes self-focused due to the weak relativistic-ponderomotive nonlinearity, we provide results for enhanced pulse compression. The results show that the matched interplay between self-focusing and self-compression can improve significantly the temporal profile of the compressed pulse. Enhanced pulse compression can be achieved by optimizing and selecting the parameters such as collision frequency, ion-temperature, and laser intensity.

  16. Laser-pulse compression in a collisional plasma under weak-relativistic ponderomotive nonlinearity

    Energy Technology Data Exchange (ETDEWEB)

    Singh, Mamta; Gupta, D. N., E-mail: dngupta@physics.du.ac.in [Department of Physics and Astrophysics, North Campus, University of Delhi, Delhi 110 007 (India)

    2016-05-15

    We present theory and numerical analysis which demonstrate laser-pulse compression in a collisional plasma under the weak-relativistic ponderomotive nonlinearity. Plasma equilibrium density is modified due to the ohmic heating of electrons, the collisions, and the weak relativistic-ponderomotive force during the interaction of a laser pulse with plasmas. First, within one-dimensional analysis, the longitudinal self-compression mechanism is discussed. Three-dimensional analysis (spatiotemporal) of laser pulse propagation is also investigated by coupling the self-compression with the self-focusing. In the regime in which the laser becomes self-focused due to the weak relativistic-ponderomotive nonlinearity, we provide results for enhanced pulse compression. The results show that the matched interplay between self-focusing and self-compression can improve significantly the temporal profile of the compressed pulse. Enhanced pulse compression can be achieved by optimizing and selecting the parameters such as collision frequency, ion-temperature, and laser intensity.

  17. Performance analysis of three-dimensional-triple-level cell and two-dimensional-multi-level cell NAND flash hybrid solid-state drives

    Science.gov (United States)

    Sakaki, Yukiya; Yamada, Tomoaki; Matsui, Chihiro; Yamaga, Yusuke; Takeuchi, Ken

    2018-04-01

    In order to improve performance of solid-state drives (SSDs), hybrid SSDs have been proposed. Hybrid SSDs consist of more than two types of NAND flash memories or NAND flash memories and storage-class memories (SCMs). However, the cost of hybrid SSDs adopting SCMs is more expensive than that of NAND flash only SSDs because of the high bit cost of SCMs. This paper proposes unique hybrid SSDs with two-dimensional (2D) horizontal multi-level cell (MLC)/three-dimensional (3D) vertical triple-level cell (TLC) NAND flash memories to achieve higher cost-performance. The 2D-MLC/3D-TLC hybrid SSD achieves up to 31% higher performance than the conventional 2D-MLC/2D-TLC hybrid SSD. The factors of different performance between the proposed hybrid SSD and the conventional hybrid SSD are analyzed by changing its block size, read/write/erase latencies, and write unit of 3D-TLC NAND flash memory, by means of a transaction-level modeling simulator.

  18. Relativistic two-body equation for one Dirac and one Duffin-Kemmer particle

    International Nuclear Information System (INIS)

    Krolikowski, W.

    1983-01-01

    A new relativistic two-body wave equation is proposed for one spin-1/2 and one spin-0 or spin-1 particle which, if isolated from each other, are described by the Dirac and the Duffin-Kemmer equation, respectively. For a static mutual interaction this equation splits into two equations: a two-body wave equation for one Dirac and one Klein-Gordon particle (which was introduced by the author previously) and a new two-body wave equation for one Dirac and one Proca particle. The proposed equation may be applied in particular to the quark-diquark system. In Appendix, however, an alternative approach is sketched, where the diquark is described as the point limit of a very close Breit system rather than a Duffin-Kemmer particle. (Author)

  19. Three-dimensional morphological imaging of human induced pluripotent stem cells by using low-coherence quantitative phase microscopy

    Science.gov (United States)

    Yamauchi, Toyohiko; Kakuno, Yumi; Goto, Kentaro; Fukami, Tadashi; Sugiyama, Norikazu; Iwai, Hidenao; Mizuguchi, Yoshinori; Yamashita, Yutaka

    2014-03-01

    There is an increasing need for non-invasive imaging techniques in the field of stem cell research. Label-free techniques are the best choice for assessment of stem cells because the cells remain intact after imaging and can be used for further studies such as differentiation induction. To develop a high-resolution label-free imaging system, we have been working on a low-coherence quantitative phase microscope (LC-QPM). LC-QPM is a Linnik-type interference microscope equipped with nanometer-resolution optical-path-length control and capable of obtaining three-dimensional volumetric images. The lateral and vertical resolutions of our system are respectively 0.5 and 0.93 μm and this performance allows capturing sub-cellular morphological features of live cells without labeling. Utilizing LC-QPM, we reported on three-dimensional imaging of membrane fluctuations, dynamics of filopodia, and motions of intracellular organelles. In this presentation, we report three-dimensional morphological imaging of human induced pluripotent stem cells (hiPS cells). Two groups of monolayer hiPS cell cultures were prepared so that one group was cultured in a suitable culture medium that kept the cells undifferentiated, and the other group was cultured in a medium supplemented with retinoic acid, which forces the stem cells to differentiate. The volumetric images of the 2 groups show distinctive differences, especially in surface roughness. We believe that our LC-QPM system will prove useful in assessing many other stem cell conditions.

  20. Quantum mechanical treatment of a constrained particle on two dimensional sphere

    Energy Technology Data Exchange (ETDEWEB)

    Jahangiri, L., E-mail: laleh.jahangiry@yahoo.com; Panahi, H., E-mail: t-panahi@guilan.ac.ir

    2016-12-15

    In this work, we study the motion of a particle on two dimensional sphere. By writing the Schrodinger equation, we obtain the wave function and energy spectra for three dimensional harmonic oscillator potential plus trigonometric Rosen–Morse non-central potential. By letting three special cases for intertwining operator, we investigate the energy spectra and wave functions for Smorodinsky–Winternitz potential model.

  1. Explosive X-point collapse in relativistic magnetically dominated plasma

    Science.gov (United States)

    Lyutikov, Maxim; Sironi, Lorenzo; Komissarov, Serguei S.; Porth, Oliver

    2017-12-01

    The extreme properties of the gamma-ray flares in the Crab nebula present a clear challenge to our ideas on the nature of particle acceleration in relativistic astrophysical plasma. It seems highly unlikely that standard mechanisms of stochastic type are at work here and hence the attention of theorists has switched to linear acceleration in magnetic reconnection events. In this series of papers, we attempt to develop a theory of explosive magnetic reconnection in highly magnetized relativistic plasma which can explain the extreme parameters of the Crab flares. In the first paper, we focus on the properties of the X-point collapse. Using analytical and numerical methods (fluid and particle-in-cell simulations) we extend Syrovatsky's classical model of such collapse to the relativistic regime. We find that the collapse can lead to the reconnection rate approaching the speed of light on macroscopic scales. During the collapse, the plasma particles are accelerated by charge-starved electric fields, which can reach (and even exceed) values of the local magnetic field. The explosive stage of reconnection produces non-thermal power-law tails with slopes that depend on the average magnetization . For sufficiently high magnetizations and vanishing guide field, the non-thermal particle spectrum consists of two components: a low-energy population with soft spectrum that dominates the number census; and a high-energy population with hard spectrum that possesses all the properties needed to explain the Crab flares.

  2. A Bioengineered Three-Dimensional Cell Culture Platform Integrated with Microfluidics To Address Antimicrobial Resistance in Tuberculosis

    Directory of Open Access Journals (Sweden)

    Magdalena K. Bielecka

    2017-02-01

    Full Text Available Antimicrobial resistance presents one of the most significant threats to human health, with the emergence of totally drug-resistant organisms. We have combined bioengineering, genetically modified bacteria, longitudinal readouts, and fluidics to develop a transformative platform to address the drug development bottleneck, utilizing Mycobacterium tuberculosis as the model organism. We generated microspheres incorporating virulent reporter bacilli, primary human cells, and an extracellular matrix by using bioelectrospray methodology. Granulomas form within the three-dimensional matrix, and mycobacterial stress genes are upregulated. Pyrazinamide, a vital first-line antibiotic for treating human tuberculosis, kills M. tuberculosis in a three-dimensional culture but not in a standard two-dimensional culture or Middlebrook 7H9 broth, demonstrating that antibiotic sensitivity within microspheres reflects conditions in patients. We then performed pharmacokinetic modeling by combining the microsphere system with a microfluidic plate and demonstrated that we can model the effect of dynamic antibiotic concentrations on mycobacterial killing. The microsphere system is highly tractable, permitting variation of cell content, the extracellular matrix, sphere size, the infectious dose, and the surrounding medium with the potential to address a wide array of human infections and the threat of antimicrobial resistance.

  3. Quantum field between moving mirrors: A three dimensional example

    Science.gov (United States)

    Hacyan, S.; Jauregui, Roco; Villarreal, Carlos

    1995-01-01

    The scalar quantum field uniformly moving plates in three dimensional space is studied. Field equations for Dirichlet boundary conditions are solved exactly. Comparison of the resulting wavefunctions with their instantaneous static counterpart is performed via Bogolubov coefficients. Unlike the one dimensional problem, 'particle' creation as well as squeezing may occur. The time dependent Casimir energy is also evaluated.

  4. Establishment of three-dimensional cultures of human pancreatic duct epithelial cells

    International Nuclear Information System (INIS)

    Gutierrez-Barrera, Angelica M.; Menter, David G.; Abbruzzese, James L.; Reddy, Shrikanth A.G.

    2007-01-01

    Three-dimensional (3D) cultures of epithelial cells offer singular advantages for studies of morphogenesis or the role of cancer genes in oncogenesis. In this study, as part of establishing a 3D culture system of pancreatic duct epithelial cells, we compared human pancreatic duct epithelial cells (HPDE-E6E7) with pancreatic cancer cell lines. Our results show, that in contrast to cancer cells, HPDE-E6E7 organized into spheroids with what appeared to be apical and basal membranes and a luminal space. Immunostaining experiments indicated that protein kinase Akt was phosphorylated (Ser473) and CTMP, a negative Akt regulator, was expressed in both HPDE-E6E7 and cancer cells. However, a nuclear pool of CTMP was detectable in HPDE-E6E7 cells that showed a dynamic concentrated expression pattern, a feature that further distinguished HPDE-E637 cells from cancer cells. Collectively, these data suggest that 3D cultures of HPDE-E6E7 cells are useful for investigating signaling and morphological abnormalities in pancreatic cancer cells

  5. Highly sensitive three-dimensional interdigitated microelectrode for microparticle detection using electrical impedance spectroscopy

    International Nuclear Information System (INIS)

    Chang, Fu-Yu; Chen, Ming-Kun; Jang, Ling-Sheng; Wang, Min-Haw

    2016-01-01

    Cell impedance analysis is widely used for monitoring biological and medical reactions. In this study, a highly sensitive three-dimensional (3D) interdigitated microelectrode (IME) with a high aspect ratio on a polyimide (PI) flexible substrate was fabricated for microparticle detection (e.g. cell quantity detection) using electroforming and lithography technology. 3D finite element simulations were performed to compare the performance of the 3D IME (in terms of sensitivity and signal-to-noise ratio) to that of a planar IME for particles in the sensing area. Various quantities of particles were captured in Dulbecco’s modified Eagle medium and their impedances were measured. With the 3D IME, the particles were arranged in the gap, not on the electrode, avoiding the noise due to particle position. For the maximum particle quantities, the results show that the 3D IME has at least 5-fold higher sensitivity than that of the planar IME. The trends of impedance magnitude and phase due to particle quantity were verified using the equivalent circuit model. The impedance (1269 Ω) of 69 particles was used to estimate the particle quantity (68 particles) with 98.6% accuracy using a parabolic regression curve at 500 kHz. (paper)

  6. Lectures on relativistic quantum mechanics and path integration

    International Nuclear Information System (INIS)

    Gunn, J.M.F.

    1989-02-01

    The question posed is why bother with relativistic quantum mechanics? Three reasons are given: First that there are many experimental phenomena which cannot be explained in non-relativistic terms. Secondly it would be unsatisfactory if relativity and quantum mechanics could not be united. Thirdly, there are theoretical reasons why new effects can be expected at relativistic velocities. The objectives of the course are to set up relativistic analogues of the Schroedinger equation and to understand their consequences. In doing so there are some questions which are raised and discussed such as can a first order equation be used to describe spin 0 particles and a second order equation be used to describe spin 1/ 2 (author)

  7. Constraints on rapidity-dependent initial conditions from charged-particle pseudorapidity densities and two-particle correlations

    Science.gov (United States)

    Ke, Weiyao; Moreland, J. Scott; Bernhard, Jonah E.; Bass, Steffen A.

    2017-10-01

    We study the initial three-dimensional spatial configuration of the quark-gluon plasma (QGP) produced in relativistic heavy-ion collisions using centrality and pseudorapidity-dependent measurements of the medium's charged particle density and two-particle correlations. A cumulant-generating function is first used to parametrize the rapidity dependence of local entropy deposition and extend arbitrary boost-invariant initial conditions to nonzero beam rapidities. The model is then compared to p +Pb and Pb + Pb charged-particle pseudorapidity densities and two-particle pseudorapidity correlations and systematically optimized using Bayesian parameter estimation to extract high-probability initial condition parameters. The optimized initial conditions are then compared to a number of experimental observables including the pseudorapidity-dependent anisotropic flows, event-plane decorrelations, and flow correlations. We find that the form of the initial local longitudinal entropy profile is well constrained by these experimental measurements.

  8. Three-Dimensional Cell Culture Models for Infectious Disease and Drug Development

    Science.gov (United States)

    Nickerson, Cheryl A.; Honer zu Bentrup, Kerstin; Ott, C. Mark

    2005-01-01

    Three-dimensional (3-D) cell cultures hold enormous potential to advance our understanding of infectious disease and to effectively translate basic cellular research into clinical applications. Using novel NASA bioreactor technology, the rotating wall vessel (RWV), we have engineered physiologically relevant 3-D human tissue culture models for infectious disease studies. The design of the RWV is based on the understanding that organs and tissues function in a 3-D environment, and that this 3-D architecture is critical for the differentiated form and function of tissues in vivo. The RWV provides large numbers of cells which are amenable to a wide variety of experimental manipulations and provides an easy, reproducible, and cost-effective approach to enhance differentiated features of cell culture models.

  9. Intense EM filamentation in relativistic hot plasmas

    Energy Technology Data Exchange (ETDEWEB)

    Hu, Qiang-Lin [Department of Physics, Jinggangshan University, Ji' an, Jiangxi 343009 (China); Chen, Zhong-Ping [Department of Physics and Institute for Fusion Studies, The University of Texas at Austin, Austin, TX 78712 (United States); Mahajan, Swadesh M., E-mail: mahajan@mail.utexas.edu [Department of Physics and Institute for Fusion Studies, The University of Texas at Austin, Austin, TX 78712 (United States); Department of Physics, School of Natural Sciences, Shiv Nadar University, Uttar Pradesh 201314 (India)

    2017-03-03

    Highlights: • Breaking up of an intense EM pulse into filaments is a spectacular demonstration of the nonlinear wave-plasma interaction. • Filaments are spectacularly sharper, highly extended and longer lived at relativistic temperatures. • EM energy concentration can trigger new nonlinear phenomena with absolute consequences for high energy density matter. - Abstract: Through 2D particle-in-cell (PIC) simulations, we demonstrate that the nature of filamentation of a high intensity electromagnetic (EM) pulse propagating in an underdense plasma, is profoundly affected at relativistically high temperatures. The “relativistic” filaments are sharper, are dramatically extended (along the direction of propagation), and live much longer than their lower temperature counterparts. The thermally boosted electron inertia is invoked to understand this very interesting and powerful phenomenon.

  10. Scattering of Non-Relativistic Charged Particles by Electromagnetic Radiation

    Science.gov (United States)

    Apostol, M.

    2017-11-01

    The cross-section is computed for non-relativistic charged particles (like electrons and ions) scattered by electromagnetic radiation confined to a finite region (like the focal region of optical laser beams). The cross-section exhibits maxima at scattering angles given by the energy and momentum conservation in multi-photon absorption or emission processes. For convenience, a potential scattering is included and a comparison is made with the well-known Kroll-Watson scattering formula. The scattering process addressed in this paper is distinct from the process dealt with in previous studies, where the scattering is immersed in the radiation field.

  11. Three-dimensional mid-air acoustic manipulation by ultrasonic phased arrays.

    Science.gov (United States)

    Ochiai, Yoichi; Hoshi, Takayuki; Rekimoto, Jun

    2014-01-01

    The essence of levitation technology is the countervailing of gravity. It is known that an ultrasound standing wave is capable of suspending small particles at its sound pressure nodes. The acoustic axis of the ultrasound beam in conventional studies was parallel to the gravitational force, and the levitated objects were manipulated along the fixed axis (i.e. one-dimensionally) by controlling the phases or frequencies of bolted Langevin-type transducers. In the present study, we considered extended acoustic manipulation whereby millimetre-sized particles were levitated and moved three-dimensionally by localised ultrasonic standing waves, which were generated by ultrasonic phased arrays. Our manipulation system has two original features. One is the direction of the ultrasound beam, which is arbitrary because the force acting toward its centre is also utilised. The other is the manipulation principle by which a localised standing wave is generated at an arbitrary position and moved three-dimensionally by opposed and ultrasonic phased arrays. We experimentally confirmed that expanded-polystyrene particles of 0.6 mm, 1 mm, and 2 mm in diameter could be manipulated by our proposed method.

  12. Three dimensional [delta][ital f] simulations of beams in the SSC

    Energy Technology Data Exchange (ETDEWEB)

    Koga, J.; Tajima, T. (Institute for Fusion Studies, The University of Texas at Austin, Austin, Texas 78712-1060 (United States)); Machida, S. (SSC Laboratory, 2550 Beckleymeade Avenue, Dallas, Texas 75237 (United States))

    1993-12-25

    A three dimensional [delta][ital f] strong-strong algorithm has been developed to apply to the study of such effects as space charge and beam-beam interaction phenomena in the Superconducting Super Collider (SSC). The algorithm is obtained from the merging of the particle tracking code Simpsons used for 3 dimensional space charge effects and a [delta][ital f] code. The [delta][ital f] method is used to follow the evolution of the non-gaussian part of the beam distribution. The advantages of this method are twofold. First, the Simpsons code utilizes a realistic accelerator model including synchrotron oscillations and energy ramping in 6 dimensional phase space with electromagnetic fields of the beams calculated using a realistic 3 dimensional field solver. Second, the beams are evolving in the fully self-consistent strong-strong sense with finite particle fluctuation noise is greatly reduced as opposed to the weak-strong models where one beam is fixed.

  13. Prediction of deformation and hygro-thermal stresses distribution in PEM fuel cell vehicle using three-dimensional CFD model

    Energy Technology Data Exchange (ETDEWEB)

    Sadiq Al-Baghdadi, Maher A.R. [Fuel Cell Research Center, International Energy & Environment Foundation, Al-Najaf, P.O.Box 39 (Iraq)

    2012-07-01

    Durability is one of the most critical remaining issues impeding successful commercialization of broad PEM fuel cell transportation energy applications. Automotive fuel cells are likely to operate with neat hydrogen under load-following or load-levelled modes and be expected to withstand variations in environmental conditions, particularly in the context of temperature and atmospheric composition. In addition, they are also required to survive over the course of their expected operational lifetimes i.e., around 5,500 hrs, while undergoing as many as 30,000 startup/shutdown cycles. The damage mechanisms in a PEM fuel cell are accelerated by mechanical stresses arising during fuel cell assembly (bolt assembling), and the stresses arise during fuel cell running, because it consists of the materials with different thermal expansion and swelling coefficients. Therefore, in order to acquire a complete understanding of the damage mechanisms in the membrane, mechanical response under steady-state hygro-thermal stresses should be studied under real cell operating conditions and in real cell geometry (three-dimensional). In this work, full three-dimensional, non-isothermal computational fluid dynamics model of a PEM fuel cell has been developed to simulate the stresses inside the PEM fuel cell, which are occurring during fuel cell assembly (bolt assembling), and the stresses arise during fuel cell running due to the changes of temperature and relative humidity. A unique feature of the present model is to incorporate the effect of hygro and thermal stresses into actual three-dimensional fuel cell model. In addition, the temperature and humidity dependent material properties are utilize in the simulation for the membrane. The model is shown to be able to understand the many interacting, complex electrochemical, transport phenomena, and stresses distribution that have limited experimental data. This model is used to study and analyse the effect of operating parameters on the

  14. Human umbilical cord mesenchymal stromal cells exhibit immature nucleus pulposus cell phenotype in a laminin-rich pseudo-three-dimensional culture system.

    Science.gov (United States)

    Chon, Brian H; Lee, Esther J; Jing, Liufang; Setton, Lori A; Chen, Jun

    2013-10-02

    Cell supplementation to the herniated or degenerated intervertebral disc (IVD) is a potential strategy to promote tissue regeneration and slow disc pathology. Human umbilical cord mesenchymal stromal cells (HUCMSCs) - originating from the Wharton's jelly - remain an attractive candidate for such endeavors with their ability to differentiate into multiple lineages. Previously, mesenchymal stem cells (MSCs) have been studied as a potential source for disc tissue regeneration. However, no studies have demonstrated that MSCs can regenerate matrix with unique characteristics matching that of immature nucleus pulposus (NP) tissues of the IVD. In our prior work, immature NP cells were found to express specific laminin isoforms and laminin-binding receptors that may serve as phenotypic markers for evaluating MSC differentiation to NP-like cells. The goal of this study is to evaluate these markers and matrix synthesis for HUCMSCs cultured in a laminin-rich pseudo-three-dimensional culture system. HUCMSCs were seeded on top of Transwell inserts pre-coated with Matrigel™, which contained mainly laminin-111. Cells were cultured under hypoxia environment with three differentiation conditions: NP differentiation media (containing 2.5% Matrigel™ solution to provide for a pseudo-three-dimensional laminin culture system) with no serum, or the same media supplemented with either insulin-like growth factor-1 (IGF-1) or transforming growth factor-β1 (TGF-β1). Cell clustering behavior, matrix production and the expression of NP-specific laminin and laminin-receptors were evaluated at days 1, 7, 13 and 21 of culture. Data show that a pseudo-three-dimensional culture condition (laminin-1 rich) promoted HUCMSC differentiation under no serum conditions. Starting at day 1, HUCMSCs demonstrated a cell clustering morphology similar to that of immature NP cells in situ and that observed for primary immature NP cells within the similar laminin-rich culture system (prior study

  15. The three-dimensional particle-in-cell simulation analysis of cavity of high power subterahertz pulsed gyrotron

    International Nuclear Information System (INIS)

    Ito, Koyu; Jiang, Weihua

    2013-01-01

    High power sub-terahertz pulsed gyrotrons for Collective Thomson Scattering (CTS) diagnostics of fusion plasmas are being developed. The typical target parameters are: output power of 100-200 kW, operation frequency of 300 GHz, and pulsed length > 10 us. In order to support experimental development, numerical simulations were carried out by using Particle-In-Cell (PIC) code MAGIC. The oscillation mode of the electromagnetic radiation was selected as TE_1_5_,_2, for which the beam parameters and cavity dimensions were determined accordingly. The simulation results have showed maximum power of 144 kW at oscillation frequency of 292.80 GHz, with oscillation efficiency of 22.15%. (author)

  16. Assembly of multiple cell gradients directed by three-dimensional microfluidic channels.

    Science.gov (United States)

    Li, Yiwei; Feng, Xiaojun; Wang, Yachao; Du, Wei; Chen, Peng; Liu, Chao; Liu, Bi-Feng

    2015-08-07

    Active control over the cell gradient is essential for understanding biological systems and the reconstitution of the functionality of many types of tissues, particularly for organ-on-a-chip. Here, we propose a three-dimensional (3D) microfluidic strategy for generating controllable cell gradients. In this approach, a homogeneous cell suspension is loaded into a 3D stair-shaped PDMS microchannel to generate a cell gradient within 10 min by sedimentation. We demonstrate that cell gradients of various profiles (exponential and piecewise linear) can be achieved by precisely controlling the height of each layer during the fabrication. With sequential seeding, we further demonstrate the generation of two overlapping cell gradients on the same glass substrate with pre-defined designs. The cell gradient-based QD cytotoxicity assay also demonstrated that cell behaviors and resistances were regulated by the changes in cell density. These results reveal that the proposed 3D microfluidic strategy provides a simple and versatile means for establishing controllable gradients in cell density, opening up a new avenue for reconstructing functional tissues.

  17. Three-dimensional effects in fracture mechanics

    International Nuclear Information System (INIS)

    Benitez, F.G.

    1991-01-01

    An overall view of the pioneering theories and works, which enlighten the three-dimensional nature of fracture mechanics during the last years is given. the main aim is not an exhaustive reviewing but the displaying of the last developments on this scientific field in a natural way. This work attempts to envisage the limits of disregarding the three-dimensional behaviour in theories, analyses and experiments. Moreover, it tries to draw attention on the scant fervour, although increasing, this three-dimensional nature of fracture has among the scientific community. Finally, a constructive discussion is presented on the use of two-dimensional solutions in the analysis of geometries which bear a three-dimensional configuration. the static two-dimensional solutions and its applications fields are reviewed. also, the static three-dimensional solutions, wherein a comparative analysis with elastoplastic and elastostatic solutions are presented. to end up, the dynamic three-dimensional solutions are compared to the asymptotic two-dimensional ones under the practical applications point of view. (author)

  18. Parallel treatment of simulation particles in particle-in-cell codes on SUPRENUM

    International Nuclear Information System (INIS)

    Seldner, D.

    1990-02-01

    This report contains the program documentation and description of the program package 2D-PLAS, which has been developed at the Nuclear Research Center Karlsruhe in the Institute for Data Processing in Technology (IDT) under the auspices of the BMFT. 2D-PLAS is a parallel program version of the treatment of the simulation particles of the two-dimensional stationary particle-in-cell code BFCPIC which has been developed at the Nuclear Research Center Karlsruhe. This parallel version has been designed for the parallel computer SUPRENUM. (orig.) [de

  19. On the dependence of quasipotential on the total energy of a two-particle system

    International Nuclear Information System (INIS)

    Kapshaj, V.N.; Savrin, V.I.

    1986-01-01

    For a system of two relativistic particles described in the framework of the Logunov-Tavkhelidze one-time approach the dependence is calculated of the one-boson exchange potential on the total energy of the system. It is shown that in spite of a nonlocal form of the quasipotential obtained, three-dimensional equations for the wave function are reduced to one-dimensional ones by means of partial expansion. Influence of the energy dependence of the quasipotential on its behaviour in the coordinate representation is discussed

  20. Relativistic impulse dynamics.

    Science.gov (United States)

    Swanson, Stanley M

    2011-08-01

    Classical electrodynamics has some annoying rough edges. The self-energy of charges is infinite without a cutoff. The calculation of relativistic trajectories is difficult because of retardation and an average radiation reaction term. By reconceptuallizing electrodynamics in terms of exchanges of impulses rather than describing it by forces and potentials, we eliminate these problems. A fully relativistic theory using photonlike null impulses is developed. Numerical calculations for a two-body, one-impulse-in-transit model are discussed. A simple relationship between center-of-mass scattering angle and angular momentum was found. It reproduces the Rutherford cross section at low velocities and agrees with the leading term of relativistic distinguishable-particle quantum cross sections (Møller, Mott) when the distance of closest approach is larger than the Compton wavelength of the particle. Magnetism emerges as a consequence of viewing retarded and advanced interactions from the vantage point of an instantaneous radius vector. Radiation reaction becomes the local conservation of energy-momentum between the radiating particle and the emitted impulse. A net action is defined that could be used in developing quantum dynamics without potentials. A reinterpretation of Newton's laws extends them to relativistic motion.

  1. Outline of a nonlinear, relativistic quantum mechanics of extended particles

    International Nuclear Information System (INIS)

    Mielke, E.W.

    1981-01-01

    A quantum theory of intrinsically extended particles similar to de Broglie's theory of the Double Solution is proposed. A rational notion of the particle's extension is enthroned by realizing its internal structure via soliton-type solutions of nonlinear, relativistic wave equations. These droplet-type waves have a quasi-objective character except for certain boundary conditions which may be subject to stochastic fluctuations. More precisely, this assumption amounts to a probabilistic description of the center of a soliton such that it would follow the conventional quantum-mechanical formalism in the limit of zero particle radius. At short interaction distances, however, a promising nonlinear and nonlocal theory emerges. This model is not only capable of achieving a conceptually satisfying synthesis of the particle-wave dualism, but may also lead to a rational resolution of epistemological problems in the quantum-theoretical measurement process. Within experimental errors the results for, e.g., the hydrogen atom can be reproduced by appropriately specifying the nature of the nonlinear self-interaction. It is speculated that field theoretical issues raised by such notions as identical particles, field quantization and renormalization are already incorporated or resolved by this nonlocal theory, at least in principle. (author)

  2. Outline of a nonlinear, relativistic quantum mechanics of extended particles

    International Nuclear Information System (INIS)

    Mielke, E.W.

    1981-01-01

    A quantum theory of intrinsically extended particles similar to de Broglie's Theory of the Double Solution is proposed. A rational notion of the particle's extension is enthroned by realizing its internal structure via soliton-type solutions of nonlinear, relativistic wave equations. These droplet-type waves have a quasi-objective character except for certain boundary conditions which may be subject to stochastic fluctuations. More precisely, this assumption amounts to a probabilistic description of the center of a soliton such that it would follow the conventional quantum-mechanical formalism in the limit of zero particle radius. At short interaction distances, however, a promising nonlinear and nonlocal theory emerges. This model is not only capable of achieving a conceptually satisfying synthesis of the particle-wave dualism, but may also lead to a rational resolution of epistemological problems in the quantum-theoretical measurement process. Within experimental errors the results for, e.g., the hydrogen atom can be reproduced by appropriately specifying the nature of the nonlinear self-interaction. It is speculated that field theoretical issues raised by such notions as identical particles, field quantization and renormalization are already incorporated or resolved by this nonlocal theory, at least in principle. (author)

  3. Backward scattering in the one-dimensional Fermi gas

    International Nuclear Information System (INIS)

    Apostol, M.

    1980-05-01

    The Ward identity is derived for non-relativistic fermions with two-body spin-independent interaction. Using this identity for the one-dimensional Fermi gas with backward scattering the equations of the perturbation theory are solved for the effective interaction and the collective excitations of the particle density fluctuations are obtained. (author)

  4. Three-dimensional intracellular structure of a whole rice mesophyll cell observed with FIB-SEM.

    Science.gov (United States)

    Oi, Takao; Enomoto, Sakiko; Nakao, Tomoyo; Arai, Shigeo; Yamane, Koji; Taniguchi, Mitsutaka

    2017-07-01

    Ultrathin sections of rice leaf blades observed two-dimensionally using a transmission electron microscope (TEM) show that the chlorenchyma is composed of lobed mesophyll cells, with intricate cell boundaries, and lined with chloroplasts. The lobed cell shape and chloroplast positioning are believed to enhance the area available for the gas exchange surface for photosynthesis in rice leaves. However, a cell image revealing the three-dimensional (3-D) ultrastructure of rice mesophyll cells has not been visualized. In this study, a whole rice mesophyll cell was observed using a focused ion beam scanning electron microscope (FIB-SEM), which provides many serial sections automatically, rapidly and correctly, thereby enabling 3-D cell structure reconstruction. Rice leaf blades were fixed chemically using the method for conventional TEM observation, embedded in resin and subsequently set in the FIB-SEM chamber. Specimen blocks were sectioned transversely using the FIB, and block-face images were captured using the SEM. The sectioning and imaging were repeated overnight for 200-500 slices (each 50 nm thick). The resultant large-volume image stacks ( x = 25 μm, y = 25 μm, z = 10-25 μm) contained one or two whole mesophyll cells. The 3-D models of whole mesophyll cells were reconstructed using image processing software. The reconstructed cell models were discoid shaped with several lobes around the cell periphery. The cell shape increased the surface area, and the ratio of surface area to volume was twice that of a cylinder having the same volume. The chloroplasts occupied half the cell volume and spread as sheets along the cell lobes, covering most of the inner cell surface, with adjacent chloroplasts in close contact with each other. Cellular and sub-cellular ultrastructures of a whole mesophyll cell in a rice leaf blade are demonstrated three-dimensionally using a FIB-SEM. The 3-D models and numerical information support the hypothesis that rice mesophyll

  5. High-Efficiency Dye-Sensitized Solar Cell with Three-Dimensional Photoanode

    KAUST Repository

    Tétreault, Nicolas

    2011-11-09

    Herein, we present a straightforward bottom-up synthesis of a high electron mobility and highly light scattering macroporous photoanode for dye-sensitized solar cells. The dense three-dimensional Al/ZnO, SnO2, or TiO 2 host integrates a conformal passivation thin film to reduce recombination and a large surface-area mesoporous anatase guest for high dye loading. This novel photoanode is designed to improve the charge extraction resulting in higher fill factor and photovoltage for DSCs. An increase in photovoltage of up to 110 mV over state-of-the-art DSC is demonstrated. © 2011 American Chemical Society.

  6. High-Efficiency Dye-Sensitized Solar Cell with Three-Dimensional Photoanode

    KAUST Repository

    Té treault, Nicolas; Arsenault, É ric; Heiniger, Leo-Philipp; Soheilnia, Navid; Brillet, Jé ré mie; Moehl, Thomas; Zakeeruddin, Shaik; Ozin, Geoffrey A.; Grä tzel, Michael

    2011-01-01

    Herein, we present a straightforward bottom-up synthesis of a high electron mobility and highly light scattering macroporous photoanode for dye-sensitized solar cells. The dense three-dimensional Al/ZnO, SnO2, or TiO 2 host integrates a conformal passivation thin film to reduce recombination and a large surface-area mesoporous anatase guest for high dye loading. This novel photoanode is designed to improve the charge extraction resulting in higher fill factor and photovoltage for DSCs. An increase in photovoltage of up to 110 mV over state-of-the-art DSC is demonstrated. © 2011 American Chemical Society.

  7. Program Package for 3d PIC Model of Plasma Fiber

    Science.gov (United States)

    Kulhánek, Petr; Břeň, David

    2007-08-01

    A fully three dimensional Particle in Cell model of the plasma fiber had been developed. The code is written in FORTRAN 95, implementation CVF (Compaq Visual Fortran) under Microsoft Visual Studio user interface. Five particle solvers and two field solvers are included in the model. The solvers have relativistic and non-relativistic variants. The model can deal both with periodical and non-periodical boundary conditions. The mechanism of the surface turbulences generation in the plasma fiber was successfully simulated with the PIC program package.

  8. A three-dimensional non-isothermal model for a membraneless direct methanol redox fuel cell

    Science.gov (United States)

    Wei, Lin; Yuan, Xianxia; Jiang, Fangming

    2018-05-01

    In the membraneless direct methanol redox fuel cell (DMRFC), three-dimensional electrodes contribute to the reduction of methanol crossover and the open separator design lowers the system cost and extends its service life. In order to better understand the mechanisms of this configuration and further optimize its performance, the development of a three-dimensional numerical model is reported in this work. The governing equations of the multi-physics field are solved based on computational fluid dynamics methodology, and the influence of the CO2 gas is taken into consideration through the effective diffusivities. The numerical results are in good agreement with experimental data, and the deviation observed for cases of large current density may be related to the single-phase assumption made. The three-dimensional electrode is found to be effective in controlling methanol crossover in its multi-layer structure, while it also increases the flow resistance for the discharging products. It is found that the current density distribution is affected by both the electronic conductivity and the concentration of reactants, and the temperature rise can be primarily attributed to the current density distribution. The sensitivity and reliability of the model are analyzed through the investigation of the effects of cell parameters, including porosity values of gas diffusion layers and catalyst layers, methanol concentration and CO2 volume fraction, on the polarization characteristics.

  9. Internal space-time symmetries of massive and massless particles and their unification

    International Nuclear Information System (INIS)

    Kim, Y.S.

    2001-01-01

    It is noted that the internal space-time symmetries of relativistic particles are dictated by Wigner's little groups. The symmetry of massive particles is like the three-dimensional rotation group, while the symmetry of massless particles is locally isomorphic to the two-dimensional Euclidean group. It is noted also that, while the rotational degree of freedom for a massless particle leads to its helicity, the two translational degrees of freedom correspond to its gauge degrees of freedom. It is shown that the E(2)-like symmetry of of massless particles can be obtained as an infinite-momentum and/or zero-mass limit of the O(3)-like symmetry of massive particles. This mechanism is illustrated in terms of a sphere elongating into a cylinder. In this way, the helicity degree of freedom remains invariant under the Lorentz boost, but the transverse rotational degrees of freedom become contracted into the gauge degree of freedom

  10. Relativistic Celestial Mechanics of the Solar System

    CERN Document Server

    Kopeikin, Sergei; Kaplan, George

    2011-01-01

    This authoritative book presents the theoretical development of gravitational physics as it applies to the dynamics of celestial bodies and the analysis of precise astronomical observations. In so doing, it fills the need for a textbook that teaches modern dynamical astronomy with a strong emphasis on the relativistic aspects of the subject produced by the curved geometry of four-dimensional spacetime. The first three chapters review the fundamental principles of celestial mechanics and of special and general relativity. This background material forms the basis for understanding relativistic r

  11. The therapeutic potential of three-dimensional multipotent mesenchymal stromal cell spheroids

    Czech Academy of Sciences Publication Activity Database

    Petrenko, Yuriy; Syková, Eva; Kubinová, Šárka

    2017-01-01

    Roč. 8, apr 26 (2017), s. 94 ISSN 1757-6512 R&D Projects: GA MŠk(CZ) LO1309; GA ČR(CZ) GA15-01396S; GA ČR(CZ) GA17-03765S; GA MŠk(CZ) LM2015064 Institutional support: RVO:68378041 Keywords : multipotent mesenchymal stromal cells * three-dimensional spheroids * clinical-grade manufacturing Subject RIV: FH - Neurology OBOR OECD: Neuroscience s (including psychophysiology Impact factor: 4.211, year: 2016

  12. A three-dimensional model of PEM fuel cells with serpentine flow channels

    International Nuclear Information System (INIS)

    Nguyen, P.T.; Berning, T.; Bang, M.; Djilali, N.

    2003-01-01

    A three-dimensional computational model of PEM fuel cell with serpentine flow field channels is presented in this paper. This model presents a comprehensive account for all important transport phenomena in fuel cell such as heat transfer, mass transfer, electrode kinetics, and potential fields in the membrane and gas diffusion layers. A new approach of solving for the potential losses across the cell was also developed in this model. The dependency of local current density on oxygen concentration and activation overpotential is fully addressed in this model. The computational domain consists of serpentine gas flow channels, porous gas diffusion layers, catalyst layers, and a membrane. Results obtained from this model are in good agreement with experimental results. (author)

  13. Coating of hydrophobins on three-dimensional electrospun poly(lactic-co-glycolic acid) scaffolds for cell adhesion

    Energy Technology Data Exchange (ETDEWEB)

    Hou Sen; Li Xinxin; Li Xiaoyu; Feng Xizeng, E-mail: xzfeng@nankai.edu.c [College of Life Science, Nankai University, Weijin Road 94, Tianjin, 300071 (China)

    2009-09-15

    Surface modification with hydrophobins is very important for cell adhesion in its applications in biosensor fabrication. In this study, we modified the surface of three-dimensional electrospun poly(lactide-co-glycolide) (PLGA) scaffolds with hydrophobin HFBI and collagen, and investigated its applications for cell adhesion. We found that HFBI could not only improve the hydrophilicity of the three-dimensional electrospun PLGA scaffolds but also endow the electrospun PLGA scaffolds with water permeability. This permeability should be attributed to both the hydrophilicity of the modified PLGA surface and the large positive capillary effect induced by the microstructures. Further experiment indicated that HFBI modification could improve collagen immobilization on the electrospun PLGA scaffolds and the HFBI/collagen modified electrospun PLGA scaffolds showed higher efficiency in promoting cell adhesion than the native PLGA scaffolds. This finding should be of potential application in biosensor device fabrication.

  14. Three-dimensional anode engineering for the direct methanol fuel cell

    Energy Technology Data Exchange (ETDEWEB)

    Bauer, A.; Oloman, C.W.; Gyenge, E.L. [Department of Chemical and Biological Engineering, The University of British Columbia, 2360 East Mall, Vancouver, BC (Canada)

    2009-09-05

    Catalyzed graphite felt three-dimensional anodes were investigated in direct methanol fuel cells (DMFCs) operated with sulfuric acid supporting electrolyte. With a conventional serpentine channel flow field the preferred anode thickness was 100 {mu}m, while a novel flow-by anode showed the best performance with a thickness of 200-300 {mu}m. The effects of altering the methanol concentration, anolyte flow rate and operating temperature on the fuel cell superficial power density were studied by full (2{sup 3} + 1) factorial experiments on a cell with anode area of 5 cm{sup 2} and excess oxidant O{sub 2} at 200 kPa(abs). For operation in the flow-by mode with 2 M methanol at 2 cm{sup 3} min{sup -1} and 353 K the peak power density was 2380 W m{sup -2} with a PtRuMo anode catalyst, while a PtRu catalyst yielded 2240 W m{sup -2} under the same conditions. (author)

  15. Three-dimensional anode engineering for the direct methanol fuel cell

    Science.gov (United States)

    Bauer, A.; Oloman, C. W.; Gyenge, E. L.

    Catalyzed graphite felt three-dimensional anodes were investigated in direct methanol fuel cells (DMFCs) operated with sulfuric acid supporting electrolyte. With a conventional serpentine channel flow field the preferred anode thickness was 100 μm, while a novel flow-by anode showed the best performance with a thickness of 200-300 μm. The effects of altering the methanol concentration, anolyte flow rate and operating temperature on the fuel cell superficial power density were studied by full (2 3 + 1) factorial experiments on a cell with anode area of 5 cm 2 and excess oxidant O 2 at 200 kPa(abs). For operation in the flow-by mode with 2 M methanol at 2 cm 3 min -1 and 353 K the peak power density was 2380 W m -2 with a PtRuMo anode catalyst, while a PtRu catalyst yielded 2240 W m -2 under the same conditions.

  16. Three-dimensional bio-printing.

    Science.gov (United States)

    Gu, Qi; Hao, Jie; Lu, YangJie; Wang, Liu; Wallace, Gordon G; Zhou, Qi

    2015-05-01

    Three-dimensional (3D) printing technology has been widely used in various manufacturing operations including automotive, defence and space industries. 3D printing has the advantages of personalization, flexibility and high resolution, and is therefore becoming increasingly visible in the high-tech fields. Three-dimensional bio-printing technology also holds promise for future use in medical applications. At present 3D bio-printing is mainly used for simulating and reconstructing some hard tissues or for preparing drug-delivery systems in the medical area. The fabrication of 3D structures with living cells and bioactive moieties spatially distributed throughout will be realisable. Fabrication of complex tissues and organs is still at the exploratory stage. This review summarize the development of 3D bio-printing and its potential in medical applications, as well as discussing the current challenges faced by 3D bio-printing.

  17. Patterned three-dimensional encapsulation of embryonic stem cells using dielectrophoresis and stereolithography.

    Science.gov (United States)

    Bajaj, Piyush; Marchwiany, Daniel; Duarte, Carlos; Bashir, Rashid

    2013-03-01

    Controlling the assembly of cells in three dimensions is very important for engineering functional tissues, drug screening, probing cell-cell/cell-matrix interactions, and studying the emergent behavior of cellular systems. Although the current methods of cell encapsulation in hydrogels can distribute them in three dimensions, these methods typically lack spatial control of multi-cellular organization and do not allow for the possibility of cell-cell contacts as seen for the native tissue. Here, we report the integration of dielectrophoresis (DEP) with stereolithography (SL) apparatus for the spatial patterning of cells on custom made gold micro-electrodes. Afterwards, they are encapsulated in poly (ethylene glycol) diacrylate (PEGDA) hydrogels of different stiffnesses. This technique can mimic the in vivo microscale tissue architecture, where the cells have a high degree of three dimensional (3D) spatial control. As a proof of concept, we show the patterning and encapsulation of mouse embryonic stem cells (mESCs) and C2C12 skeletal muscle myoblasts. mESCs show high viability in both the DEP (91.79% ± 1.4%) and the no DEP (94.27% ± 0.5%) hydrogel samples. Furthermore, we also show the patterning of mouse embryoid bodies (mEBs) and C2C12 spheroids in the hydrogels, and verify their viability. This robust and flexible in vitro platform can enable various applications in stem cell differentiation and tissue engineering by mimicking elements of the native 3D in vivo cellular micro-environment. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  18. Relativistic particles coupled to Chern-Simons term-revisited

    International Nuclear Information System (INIS)

    Chakraborty, B.

    1995-01-01

    The author considers the model of N relativistic spinless particles coupled to an abelian Chern-Simons term. Rewriting the action in a time reparamaterized form by introducing an arbitary parameter, parameterizing the world line of the particles, the author makes a classical constraint Hamiltonian analysis of the model. Subsequent to gauge fixing by equating the arbitrary parameter with the time the author identifies the Hamiltonian of the system, which agrees with the Hamiltonian obtained by using Banerjee's method of fixing the arbitrary Langrange multiplier by using equations of motion. The author exhibits the Poincare invariance of the model, at the classical level, by constructing spacetime generators using either the canonical or symmetric definition of the energy-momentum tensor. A detailed comparison of the expressions of angular momentum obtained by both methods show that both agree up to a boundary term. In presence of rotationally symmetric vortex configuration this term can be interpreted as an anomalous angular momentum term. The author also heuristically discusses the effect of gauge fixing on the transformation properties. 13 refs

  19. Three dimensional model for particle saltation close to stream beds, including a detailed description of the particle interaction with turbulence and inter-particle collisions

    KAUST Repository

    Moreno, Pablo M.

    2011-05-19

    We present in this paper a new three-dimensional (3-D) model for bed-load sediment transport, based on a Lagrangian description. We analyze generalized sub-models for the velocities after collision and the representation of the bed-roughness. The free-flight sub-model includes the effect of several forces, such as buoyancy, drag, virtual mass, lift, Basset and Magnus, and also addresses the particle rotation. A recent methodology for saving computational time in the Basset force is also employed. The sub-models for the post-collision velocity and rotation are based on the conservation of linear and angular momentum during the collision with the bed. We develop a new 3-D representation for the bed roughness by using geometric considerations. In order to address the interaction of particles with the turbulent flow, we tracked the particles through a computed turbulent velocity field for a smooth flat plate. This velocity field was used as a surrogate of the 3-D turbulent conditions close to the bed in streams. We first checked that the basic turbulence statistics for this velocity field could be used to approximate those in an open-channel flow. We then analyzed the interaction of the sediment and the turbulence for a single and multiple particles. We compared numerical results with experimental data obtained by Niño and García (1998b). We show that model predictions are in good agreement with existing data, in the sand size range. © 2011 ASCE.

  20. Three dimensional model for particle saltation close to stream beds, including a detailed description of the particle interaction with turbulence and inter-particle collisions

    KAUST Repository

    Moreno, Pablo M.; Bombardelli, Fabiá n A.; Gonzá lez, Andrea E.; Calo, Victor M.

    2011-01-01

    We present in this paper a new three-dimensional (3-D) model for bed-load sediment transport, based on a Lagrangian description. We analyze generalized sub-models for the velocities after collision and the representation of the bed-roughness. The free-flight sub-model includes the effect of several forces, such as buoyancy, drag, virtual mass, lift, Basset and Magnus, and also addresses the particle rotation. A recent methodology for saving computational time in the Basset force is also employed. The sub-models for the post-collision velocity and rotation are based on the conservation of linear and angular momentum during the collision with the bed. We develop a new 3-D representation for the bed roughness by using geometric considerations. In order to address the interaction of particles with the turbulent flow, we tracked the particles through a computed turbulent velocity field for a smooth flat plate. This velocity field was used as a surrogate of the 3-D turbulent conditions close to the bed in streams. We first checked that the basic turbulence statistics for this velocity field could be used to approximate those in an open-channel flow. We then analyzed the interaction of the sediment and the turbulence for a single and multiple particles. We compared numerical results with experimental data obtained by Niño and García (1998b). We show that model predictions are in good agreement with existing data, in the sand size range. © 2011 ASCE.

  1. Load-balancing techniques for a parallel electromagnetic particle-in-cell code

    Energy Technology Data Exchange (ETDEWEB)

    PLIMPTON,STEVEN J.; SEIDEL,DAVID B.; PASIK,MICHAEL F.; COATS,REBECCA S.

    2000-01-01

    QUICKSILVER is a 3-d electromagnetic particle-in-cell simulation code developed and used at Sandia to model relativistic charged particle transport. It models the time-response of electromagnetic fields and low-density-plasmas in a self-consistent manner: the fields push the plasma particles and the plasma current modifies the fields. Through an LDRD project a new parallel version of QUICKSILVER was created to enable large-scale plasma simulations to be run on massively-parallel distributed-memory supercomputers with thousands of processors, such as the Intel Tflops and DEC CPlant machines at Sandia. The new parallel code implements nearly all the features of the original serial QUICKSILVER and can be run on any platform which supports the message-passing interface (MPI) standard as well as on single-processor workstations. This report describes basic strategies useful for parallelizing and load-balancing particle-in-cell codes, outlines the parallel algorithms used in this implementation, and provides a summary of the modifications made to QUICKSILVER. It also highlights a series of benchmark simulations which have been run with the new code that illustrate its performance and parallel efficiency. These calculations have up to a billion grid cells and particles and were run on thousands of processors. This report also serves as a user manual for people wishing to run parallel QUICKSILVER.

  2. Load-balancing techniques for a parallel electromagnetic particle-in-cell code

    International Nuclear Information System (INIS)

    Plimpton, Steven J.; Seidel, David B.; Pasik, Michael F.; Coats, Rebecca S.

    2000-01-01

    QUICKSILVER is a 3-d electromagnetic particle-in-cell simulation code developed and used at Sandia to model relativistic charged particle transport. It models the time-response of electromagnetic fields and low-density-plasmas in a self-consistent manner: the fields push the plasma particles and the plasma current modifies the fields. Through an LDRD project a new parallel version of QUICKSILVER was created to enable large-scale plasma simulations to be run on massively-parallel distributed-memory supercomputers with thousands of processors, such as the Intel Tflops and DEC CPlant machines at Sandia. The new parallel code implements nearly all the features of the original serial QUICKSILVER and can be run on any platform which supports the message-passing interface (MPI) standard as well as on single-processor workstations. This report describes basic strategies useful for parallelizing and load-balancing particle-in-cell codes, outlines the parallel algorithms used in this implementation, and provides a summary of the modifications made to QUICKSILVER. It also highlights a series of benchmark simulations which have been run with the new code that illustrate its performance and parallel efficiency. These calculations have up to a billion grid cells and particles and were run on thousands of processors. This report also serves as a user manual for people wishing to run parallel QUICKSILVER

  3. Relativistic Channeling of a Picosecond Laser Pulse in a Near-Critical Preformed Plasma

    International Nuclear Information System (INIS)

    Borghesi, M.; MacKinnon, A.J.; Barringer, L.; Gaillard, R.; Gizzi, L.; Meyer, C.; Willi, O.; Pukhov, A.; Meyer-ter-Vehn, J.

    1997-01-01

    Relativistic self-channeling of a picosecond laser pulse in a preformed plasma near critical density has been observed both experimentally and in 3D particle-in-cell simulations. Optical probing measurements indicate the formation of a single pulsating propagation channel, typically of about 5μm in diameter. The computational results reveal the importance in the channel formation of relativistic electrons traveling with the light pulse and of the corresponding self-generated magnetic field. copyright 1997 The American Physical Society

  4. Particle-in-cell simulations of plasma accelerators and electron-neutral collisions

    Directory of Open Access Journals (Sweden)

    David L. Bruhwiler

    2001-10-01

    Full Text Available We present 2D simulations of both beam-driven and laser-driven plasma wakefield accelerators, using the object-oriented particle-in-cell code XOOPIC, which is time explicit, fully electromagnetic, and capable of running on massively parallel supercomputers. Simulations of laser-driven wakefields with low \\(∼10^{16} W/cm^{2}\\ and high \\(∼10^{18} W/cm^{2}\\ peak intensity laser pulses are conducted in slab geometry, showing agreement with theory and fluid simulations. Simulations of the E-157 beam wakefield experiment at the Stanford Linear Accelerator Center, in which a 30 GeV electron beam passes through 1 m of preionized lithium plasma, are conducted in cylindrical geometry, obtaining good agreement with previous work. We briefly describe some of the more significant modifications to XOOPIC required by this work, and summarize the issues relevant to modeling relativistic electron-neutral collisions in a particle-in-cell code.

  5. Sub-15 fs multiphoton lithography of three-dimensional structures for live cell applications

    International Nuclear Information System (INIS)

    Licht, Martin; Uchugonova, Aisada; König, Karsten; Straub, Martin

    2012-01-01

    Development, morphology and intratissue location of cells are influenced by the 3D nano- and microenvironment. In this paper we demonstrate multiphoton photopolymerization to generate three-dimensional structures for cell culture applications with micro- and nanotopographic features using SU-8 photoresist and mr-NIL 6000 nanoimprint resist. Moving the focal spot of high-repetition rate near-infrared sub-15 fs pulsed laser light by a galvanometric beam scanner in combination with a piezoelectric vertical stage, nearly arbitrary trajectories of polymerized photoresist were generated. This technique can be used to generate cage structures with submicron interior features for live cell applications. Preliminary experiments with PC-3 and HT-1080 cells indicate the influence of the structures on cell behavior. (paper)

  6. Classical particle limit of non-relativistic quantum mechanics

    International Nuclear Information System (INIS)

    Zucchini, R.

    1984-01-01

    We study the classical particle limit of non-relativistic quantum mechanics. We show that the unitary group describing the evolution of the quantum fluctuation around any classical phase orbit has a classical limit as h → 0 in the strong operator topology for a very large class of time independent scalar and vector potentials, which in practice covers all physically interesting cases. We also show that the mean values of the quantum mechanical position and velocity operators on suitable states, obtained by time evolution of the product of a Weyl operator centred around the large coordinates and momenta and a fixed n-independent wave function, converge to the solution of the classical equations with initial data as h → 0 for a broad class of repulsive interactions

  7. Chaos and maps in relativistic rynamical systems

    Directory of Open Access Journals (Sweden)

    L. P. Horwitz

    2000-01-01

    Full Text Available The basic work of Zaslavskii et al showed that the classical non-relativistic electromagnetically kicked oscillator can be cast into the form of an iterative map on the phase space; the resulting evolution contains a stochastic flow to unbounded energy. Subsequent studies have formulated the problem in terms of a relativistic charged particle in interaction with the electromagnetic field. We review the structure of the covariant Lorentz force used to study this problem. We show that the Lorentz force equation can be derived as well from the manifestly covariant mechanics of Stueckelberg in the presence of a standard Maxwell field, establishing a connection between these equations and mass shell constraints. We argue that these relativistic generalizations of the problem are intrinsically inaccurate due to an inconsistency in the structure of the relativistic Lorentz force, and show that a reformulation of the relativistic problem, permitting variations (classically in both the particle mass and the effective “mass” of the interacting electromagnetic field, provides a consistent system of classical equations for describing such processes.

  8. Three-dimensional mid-air acoustic manipulation by ultrasonic phased arrays.

    Directory of Open Access Journals (Sweden)

    Yoichi Ochiai

    Full Text Available The essence of levitation technology is the countervailing of gravity. It is known that an ultrasound standing wave is capable of suspending small particles at its sound pressure nodes. The acoustic axis of the ultrasound beam in conventional studies was parallel to the gravitational force, and the levitated objects were manipulated along the fixed axis (i.e. one-dimensionally by controlling the phases or frequencies of bolted Langevin-type transducers. In the present study, we considered extended acoustic manipulation whereby millimetre-sized particles were levitated and moved three-dimensionally by localised ultrasonic standing waves, which were generated by ultrasonic phased arrays. Our manipulation system has two original features. One is the direction of the ultrasound beam, which is arbitrary because the force acting toward its centre is also utilised. The other is the manipulation principle by which a localised standing wave is generated at an arbitrary position and moved three-dimensionally by opposed and ultrasonic phased arrays. We experimentally confirmed that expanded-polystyrene particles of 0.6 mm, 1 mm, and 2 mm in diameter could be manipulated by our proposed method.

  9. 3D radiation sensors with three dimensional electrodes

    CERN Document Server

    Da Via, Cinzia; Parker, Sherwood

    2018-01-01

    This book covers the technical properties, fabrication details, measurement results and applications of three-dimensional silicon radiation sensors. Such devices are currently used in the ATLAS experiment at the European Centre for Particle Physics (CERN) for particle tracking in high energy physics. They are the radiation hardest devices ever fabricated. They have applications in neutron detection, medical dosimetry and space. Written by the leading names in this field, the book explains to non-experts the essential features of silicon particle detectors, interactions of radiation with matter, radiation damage effects, and micro-fabrication. It also provides an historical view of the above.

  10. A One-Dimensional Particle-in-Cell Model of Plasma Build-Up in Vacuum Arcs

    CERN Document Server

    Timko, H; Kovermann, J; Taborelli, M; Nordlund, K; Descoeudres, A; Schneider, R; Calatroni, S; Matyash, K; Wuensch, W; Hansen, A; Grudiev, A

    2011-01-01

    Understanding the mechanism of plasma build-up in vacuum arcs is essential in many fields of physics. A one-dimensional particle-in-cell computer simulation model is presented, which models the plasma developing from a field emitter tip under electrical breakdown conditions, taking into account the relevant physical phenomena. As a starting point, only an external electric field and an initial enhancement factor of the tip are assumed. General requirements for plasma formation have been identified and formulated in terms of the initial local field and a critical neutral density. The dependence of plasma build-up on tip melting current, the evaporation rate of neutrals and external circuit time constant has been investigated for copper and simulations imply that arcing involves melting currents around 0.5-1 A/mu m(2),evaporation of neutrals to electron field emission ratios in the regime 0.01 - 0.05, plasma build-up timescales in the order of similar to 1 - 10 ns and two different regimes depending on initial ...

  11. Finiteness of the discrete spectrum of the three-particle Schroedinger operator

    International Nuclear Information System (INIS)

    Abdullaev, Janikul I.; Khalkhujaev, Axmad, M.

    2001-08-01

    We analyse the spectrum of the three-particle Schroedinger operator with pair contact and three-particle interactions on the neighboring nodes on a three-dimensional lattice. We show that the essential spectrum of this operator is the union of two segments, one of which coincides with the spectrum of an unperturbed operator and the other called two-particle branch. We will prove finiteness of the discrete spectrum of the Schroedinger operator at all parameter values of the problem. (author)

  12. Studies of the nuclear three-body system with three dimensional Faddeev calculations

    Science.gov (United States)

    Liu, Hang

    A three-body system consists of either a bound state of three particles with definite binding energy or a beam of single particles scattered from a target, where two of the particles are bound. Of the particles are nucleons, the interactions between them are strong and short ranged. A theoretical framework for studying the dynamics of a nuclear three-body system is the Faddeev scheme. In this work the equation for three-body scattering and the bound state are formulated in momentum space, and directly solved in terms of vector variables. For three identical bosons the Faddeev equation for scattering is a three- dimensional inhomogeneous integral equation in five variables, and is solved by Padé summation. The equation for the bound state is a homogeneous one in three variables, and is solved by a Lanczos' type method. The corresponding algorithms are presented, and their numerical feasibility is demonstrated. Elastic as well as inelastic scattering processes in the intermediate energy regime up to 1 GeV incident energy are studied for the first within a Faddeev scheme. The two-body force employed is of Malfliet-Tjon type. Specific emphasis is placed on studying the convergence of the multiple scattering series given by the Faddeev equations. For the bound state, a three-body force of Fujita- Miyazawa type is incorporated in addition to the two-body force. The effects of this three-body force on the bound state properties are investigated.

  13. Degradation-mediated cellular traction directs stem cell fate in covalently crosslinked three-dimensional hydrogels

    Science.gov (United States)

    Khetan, Sudhir; Guvendiren, Murat; Legant, Wesley R.; Cohen, Daniel M.; Chen, Christopher S.; Burdick, Jason A.

    2013-05-01

    Although cell-matrix adhesive interactions are known to regulate stem cell differentiation, the underlying mechanisms, in particular for direct three-dimensional encapsulation within hydrogels, are poorly understood. Here, we demonstrate that in covalently crosslinked hyaluronic acid (HA) hydrogels, the differentiation of human mesenchymal stem cells (hMSCs) is directed by the generation of degradation-mediated cellular traction, independently of cell morphology or matrix mechanics. hMSCs within HA hydrogels of equivalent elastic moduli that permit (restrict) cell-mediated degradation exhibited high (low) degrees of cell spreading and high (low) tractions, and favoured osteogenesis (adipogenesis). Moreover, switching the permissive hydrogel to a restrictive state through delayed secondary crosslinking reduced further hydrogel degradation, suppressed traction, and caused a switch from osteogenesis to adipogenesis in the absence of changes to the extended cellular morphology. Furthermore, inhibiting tension-mediated signalling in the permissive environment mirrored the effects of delayed secondary crosslinking, whereas upregulating tension induced osteogenesis even in the restrictive environment.

  14. Three-dimensional spheroid cell culture of umbilical cord tissue-derived mesenchymal stromal cells leads to enhanced paracrine induction of wound healing.

    Science.gov (United States)

    Santos, Jorge M; Camões, Sérgio P; Filipe, Elysse; Cipriano, Madalena; Barcia, Rita N; Filipe, Mariana; Teixeira, Mariana; Simões, Sandra; Gaspar, Manuela; Mosqueira, Diogo; Nascimento, Diana S; Pinto-do-Ó, Perpétua; Cruz, Pedro; Cruz, Helder; Castro, Matilde; Miranda, Joana P

    2015-05-09

    The secretion of trophic factors by mesenchymal stromal cells has gained increased interest given the benefits it may bring to the treatment of a variety of traumatic injuries such as skin wounds. Herein, we report on a three-dimensional culture-based method to improve the paracrine activity of a specific population of umbilical cord tissue-derived mesenchymal stromal cells (UCX®) towards the application of conditioned medium for the treatment of cutaneous wounds. A UCX® three-dimensional culture model was developed and characterized with respect to spheroid formation, cell phenotype and cell viability. The secretion by UCX® spheroids of extracellular matrix proteins and trophic factors involved in the wound-healing process was analysed. The skin regenerative potential of UCX® three-dimensional culture-derived conditioned medium (CM3D) was also assessed in vitro and in vivo against UCX® two-dimensional culture-derived conditioned medium (CM2D) using scratch and tubulogenesis assays and a rat wound splinting model, respectively. UCX® spheroids kept in our three-dimensional system remained viable and multipotent and secreted considerable amounts of vascular endothelial growth factor A, which was undetected in two-dimensional cultures, and higher amounts of matrix metalloproteinase-2, matrix metalloproteinase-9, hepatocyte growth factor, transforming growth factor β1, granulocyte-colony stimulating factor, fibroblast growth factor 2 and interleukin-6, when compared to CM2D. Furthermore, CM3D significantly enhanced elastin production and migration of keratinocytes and fibroblasts in vitro. In turn, tubulogenesis assays revealed increased capillary maturation in the presence of CM3D, as seen by a significant increase in capillary thickness and length when compared to CM2D, and increased branching points and capillary number when compared to basal medium. Finally, CM3D-treated wounds presented signs of faster and better resolution when compared to untreated and CM

  15. Thermodynamic laws and equipartition theorem in relativistic Brownian motion.

    Science.gov (United States)

    Koide, T; Kodama, T

    2011-06-01

    We extend the stochastic energetics to a relativistic system. The thermodynamic laws and equipartition theorem are discussed for a relativistic Brownian particle and the first and the second law of thermodynamics in this formalism are derived. The relation between the relativistic equipartition relation and the rate of heat transfer is discussed in the relativistic case together with the nature of the noise term.

  16. Three-dimensional collagen I promotes gemcitabine resistance in vitro in pancreatic cancer cells through HMGA2-dependent histone acetyltransferase expression.

    Directory of Open Access Journals (Sweden)

    Surabhi Dangi-Garimella

    Full Text Available Pancreatic ductal adenocarcinoma (PDAC is associated with a pronounced collagen-rich stromal reaction that has been shown to contribute to chemo-resistance. We have previously shown that PDAC cells are resistant to gemcitabine chemotherapy in the collagen microenvironment because of increased expression of the chromatin remodeling protein high mobility group A2 (HMGA2. We have now found that human PDAC tumors display higher levels of histone H3K9 and H3K27 acetylation in fibrotic regions. We show that relative to cells grown on tissue culture plastic, PDAC cells grown in three-dimensional collagen gels demonstrate increased histone H3K9 and H3K27 acetylation, along with increased expression of p300, PCAF and GCN5 histone acetyltransferases (HATs. Knocking down HMGA2 attenuates the effect of collagen on histone H3K9 and H3K27 acetylation and on collagen-induced p300, PCAF and GCN5 expression. We also show that human PDAC tumors with HMGA2 demonstrate increased histone H3K9 and H3K27 acetylation. Additionally, we show that cells in three-dimensional collagen gels demonstrate increased protection against gemcitabine. Significantly, down-regulation of HMGA2 or p300, PCAF and GCN5 HATs sensitizes the cells to gemcitabine in three-dimensional collagen. Overall, our results increase our understanding of how the collagen microenvironment contributes to chemo-resistance in vitro and identify HATs as potential therapeutic targets against this deadly cancer.

  17. Inertia-dependent dynamics of three-dimensional vesicles and red blood cells in shear flow.

    Science.gov (United States)

    Luo, Zheng Yuan; Wang, Shu Qi; He, Long; Xu, Feng; Bai, Bo Feng

    2013-10-28

    A three-dimensional (3D) simulation study of the effect of inertia on the dynamics of vesicles and red blood cells (RBCs) has not been reported. Here, we developed a 3D model based on the front tracking method to investigate how inertia affects the dynamics of spherical/non-spherical vesicles and biconcave-shaped RBCs with the Reynolds number ranging from 0.1 to 10. The results showed that inertia induced non-spherical vesicles transitioned from tumbling to swinging, which was not observed in previous 2D models. The critical viscosity ratio of inner/outer fluids for the tumbling–swinging transition remarkably increased with an increasing Reynolds number. The deformation of vesicles was greatly enhanced by inertia, and the frequency of tumbling and tank-treading was significantly decreased by inertia. We also found that RBCs can transit from tumbling to steady tank-treading through the swinging regime when the Reynolds number increased from 0.1 to 10. These results indicate that inertia needs to be considered at moderate Reynolds number (Re ~ 1) in the study of blood flow in the human body and the flow of deformable particle suspension in inertial microfluidic devices. The developed 3D model provided new insights into the dynamics of RBCs under shear flow, thus holding great potential to better understand blood flow behaviors under normal/disease conditions.

  18. Coherent states on horospheric three-dimensional Lobachevsky space

    Energy Technology Data Exchange (ETDEWEB)

    Kurochkin, Yu., E-mail: y.kurochkin@ifanbel.bas-net.by; Shoukavy, Dz., E-mail: shoukavy@ifanbel.bas-net.by [Institute of Physics, National Academy of Sciences of Belarus, 68 Nezalezhnasci Ave., Minsk 220072 (Belarus); Rybak, I., E-mail: Ivan.Rybak@astro.up.pt [Institute of Physics, National Academy of Sciences of Belarus, 68 Nezalezhnasci Ave., Minsk 220072 (Belarus); Instituto de Astrofísica e Ciências do Espaço, CAUP, Rua das Estrelas, 4150-762 Porto (Portugal); Faculdade de Ciências, Universidade do Porto, Rua do Campo Alegre 687, 4169-007 Porto (Portugal)

    2016-08-15

    In the paper it is shown that due to separation of variables in the Laplace-Beltrami operator (Hamiltonian of a free quantum particle) in horospheric and quasi-Cartesian coordinates of three dimensional Lobachevsky space, it is possible to introduce standard (“conventional” according to Perelomov [Generalized Coherent States and Their Applications (Springer-Verlag, 1986), p. 320]) coherent states. Some problems (oscillator on horosphere, charged particle in analogy of constant uniform magnetic field) where coherent states are suitable for treating were considered.

  19. Three-dimensional investigation of the two-phase flow structure in a bubbly pipe flow

    International Nuclear Information System (INIS)

    Schmidl, W.; Hassan, Y.A.; Ortiz-Villafuerte, J.

    1996-01-01

    Particle image velocimetry (PIV) is a nonintrusive measurement technique that can be used to study the structure of various fluid flows. PIV is used to measure the time-varying, full-field velocity data of a particle-seeded flow field within either a two-dimensional plane or three-dimensional volume. PIV is a very efficient measurement technique since it can obtain both qualitative and quantitative spatial information about the flow field being studied. The quantitative spatial velocity information can be further processed into information of flow parameters such as vorticity and turbulence over extended areas. The objective of this study was to apply recent advances and improvements in the PIV flow measurement technique to the full-field, nonintrusive analysis of a three-dimensional, two-phase fluid flow system in such a manner that both components of the two-phase system could be experimentally quantified

  20. Relativistic equations

    International Nuclear Information System (INIS)

    Gross, F.

    1986-01-01

    Relativistic equations for two and three body scattering are discussed. Particular attention is paid to relativistic three body kinetics because of recent form factor measurements of the Helium 3 - Hydrogen 3 system recently completed at Saclay and Bates and the accompanying speculation that relativistic effects are important for understanding the three nucleon system. 16 refs., 4 figs