WorldWideScience

Sample records for three-dimensional radiative discs

  1. Three-dimensional disc-satellite interaction: torques, migration, and observational signatures

    Science.gov (United States)

    Arzamasskiy, Lev; Zhu, Zhaohuan; Stone, James M.

    2018-04-01

    The interaction of a satellite with a gaseous disc results in the excitation of spiral density waves, which remove angular momentum from the orbit. In addition, if the orbit is not coplanar with the disc, three-dimensional effects will excite bending and eccentricity waves. We perform three-dimensional hydrodynamic simulations to study nonlinear disc-satellite interaction in inviscid protoplanetary discs for a variety of orbital inclinations from 0° to 180°. It is well known that three-dimensional effects are important even for zero inclination. In this work, we (1) show that for planets with small inclinations (as in the Solar system), effects such as the total torque and migration rate strongly depend on the inclination and are significantly different (about 2.5 times smaller) from the two-dimensional case, (2) give formulae for the migration rate, inclination damping, and precession rate of planets with different inclination angles in disc with different scale heights, and (3) present the observational signatures of a planet on an inclined orbit with respect to the protoplanetary disc. For misaligned planets, we find good agreement with linear theory in the limit of small inclinations, and with dynamical friction estimates for intermediate inclinations. We find that in the latter case, the dynamical friction force is not parallel to the relative planetary velocity. Overall, the derived formulae will be important for studying exoplanets with obliquity.

  2. Three-dimensional radiation treatment planning

    International Nuclear Information System (INIS)

    Mohan, R.

    1989-01-01

    A major aim of radiation therapy is to deliver sufficient dose to the tumour volume to kill the cancer cells while sparing the nearby health organs to prevent complications. With the introduction of devices such as CT and MR scanners, radiation therapy treatment planners have access to full three-dimensional anatomical information to define, simulate, and evaluate treatments. There are a limited number of prototype software systems that allow 3D treatment planning currently in use. In addition, there are more advanced tools under development or still in the planning stages. They require sophisticated graphics and computation equipment, complex physical and mathematical algorithms, and new radiation treatment machines that deliver dose very precisely under computer control. Components of these systems include programs for the identification and delineation of the anatomy and tumour, the definition of radiation beams, the calculation of dose distribution patterns, the display of dose on 2D images and as three dimensional surfaces, and the generation of computer images to verify proper patient positioning in treatment. Some of these functions can be performed more quickly and accurately if artificial intelligence or expert systems techniques are employed. 28 refs., figs

  3. Modelling three-dimensional distribution of photosynthetically active radiation in sloping coniferous stands

    International Nuclear Information System (INIS)

    Knyazikhin, Yu.; Kranigk, J.; Miessen, G.; Panfyorov, O.; Vygodskaya, N.; Gravenhorst, G.

    1996-01-01

    Solar irradiance is a major environmental factor governing biological and physiological processes in a vegetation canopy. Solar radiation distribution in a canopy and its effect are three-dimensional in nature. However, most of the radiation models up to now have been one-dimensional. They can be successfully applied to large-scale studies of forest functioning. The one-dimensional modelling technique, however, does not provide adequate interpretation of small scale processes leading to forest growth. In this article we discuss a modelling strategy for the simulation of three-dimensional radiation distribution in a vegetation canopy of a small area (about 0.25–0.3 ha). We demonstrate its realisation to predict the three-dimensional radiative regime of phytosynthetically active radiation in a real coniferous stand located on hilly surroundings. Our model can be used to investigate the influence of different climatic conditions, forest management methods and field sites on the solar energy available for forest growth in small heterogeneous areas. Further, a three-dimensional process-oriented model helps to derive global variables affecting bio-physiological processes in a vegetation canopy shifting from small scale studies of the functioning of forests to regional, continental, and global scale problems. (author)

  4. 3D radiation sensors with three dimensional electrodes

    CERN Document Server

    Da Via, Cinzia; Parker, Sherwood

    2018-01-01

    This book covers the technical properties, fabrication details, measurement results and applications of three-dimensional silicon radiation sensors. Such devices are currently used in the ATLAS experiment at the European Centre for Particle Physics (CERN) for particle tracking in high energy physics. They are the radiation hardest devices ever fabricated. They have applications in neutron detection, medical dosimetry and space. Written by the leading names in this field, the book explains to non-experts the essential features of silicon particle detectors, interactions of radiation with matter, radiation damage effects, and micro-fabrication. It also provides an historical view of the above.

  5. Three-dimensional transfer of solar radiation in clouds

    International Nuclear Information System (INIS)

    Davies, R.

    1976-01-01

    The results of a theoretical study of the effects of cloud geometry on the transfer of incident solar radiation is presented. These results indicate that a three-dimensional description of cloud geometry is a necessary prerequisite to the accurate determination of the emerging radiation field. Models which make the plane parallel assumption are therefore frequently inadequate. Both a Monte Carlo method and an analytic method were used to model the three-dimensional transfer of radiation. At the expense of considerable computation time the Monte Carlo model provides accurate values of the fluxes and intensities (averages over π/30 steradians) emerging from clouds which can be described as a set of connected cuboidal cells, each cell being homogeneous with respect to extinction coefficient, single scatter albedo and phase function. The analytic model, based on an extension of Eddington's approximation to three dimensions and to anisotropic scattering, is efficient to use, but is restricted to clouds made up of a single cuboidal cell and is more accurate for large clouds than small ones. By an iterated approach, involving integration of the source function along line of sight, the analytic model provides both fluxes and intensities of the emerging radiation at any specified point on the cloud's surface. These models were both applied to a systematic study of the transfer of solar radiation in isolated cuboidal clouds of arbitraty dimensions, the results of which illustrate the importance of considering the total cloud geometry in any attempt at realistic modelling. A study of the transfer of radiation in stratiform clouds with turretted top surfaces also indicated that even for these clouds the plane parallel assumption was often not tenable

  6. Three-dimensional dose-response models of risk for radiation injury carcinogenesis

    International Nuclear Information System (INIS)

    Raabe, O.G.

    1988-01-01

    The use of computer graphics in conjunction with three-dimensional models of dose-response relationships for chronic exposure to ionizing radiation dramaticly clarifies the separate and interactive roles of competing risks. The three dimensions are average dose rate, exposure time, and risk. As an example, the functionally injurious and carcinogenic responses after systemic uptake of Ra-226 by beagles, mice and people with consequent alpha particle irradiation of the bone are represented by three-dimensional dose-rate/time/response surfaces that demonstrate the contributions with the passage of time of the competing deleterious responses. These relationships are further evaluated by mathematical stripping with three-dimensional illustrations that graphically show the resultant separate contribution of each effect. Radiation bone injury predominates at high dose rates and bone cancer at intermediate dose rates. Low dose rates result in spontaneous deaths from natural aging, yielding a type of practical threshold for bone cancer induction. Risk assessment is benefited by the insights that become apparent with these three-dimensional models. The improved conceptualization afforded by them contributes to planning and evaluating epidemiological analyses and experimental studies

  7. High-energy radiation from collisions of high-velocity clouds and the Galactic disc

    Science.gov (United States)

    del Valle, Maria V.; Müller, A. L.; Romero, G. E.

    2018-04-01

    High-velocity clouds (HVCs) are interstellar clouds of atomic hydrogen that do not follow normal Galactic rotation and have velocities of a several hundred kilometres per second. A considerable number of these clouds are falling down towards the Galactic disc. HVCs form large and massive complexes, so if they collide with the disc a great amount of energy would be released into the interstellar medium. The cloud-disc interaction produces two shocks: one propagates through the cloud and the other through the disc. The properties of these shocks depend mainly on the cloud velocity and the disc-cloud density ratio. In this work, we study the conditions necessary for these shocks to accelerate particles by diffusive shock acceleration and we study the non-thermal radiation that is produced. We analyse particle acceleration in both the cloud and disc shocks. Solving a time-dependent two-dimensional transport equation for both relativistic electrons and protons, we obtain particle distributions and non-thermal spectral energy distributions. In a shocked cloud, significant synchrotron radio emission is produced along with soft gamma rays. In the case of acceleration in the shocked disc, the non-thermal radiation is stronger; the gamma rays, of leptonic origin, might be detectable with current instruments. A large number of protons are injected into the Galactic interstellar medium, and locally exceed the cosmic ray background. We conclude that under adequate conditions the contribution from HVC-disc collisions to the galactic population of relativistic particles and the associated extended non-thermal radiation might be important.

  8. Radiation therapy treatment planning: CT, MR imaging and three-dimensional planning

    International Nuclear Information System (INIS)

    Lichter, A.S.

    1987-01-01

    The accuracy and sophistication of radiation therapy treatment planning have increased rapidly in the last decade. Currently, CT-based treatment planning is standard throughout the country. Care must be taken when CT is used for treatment planning because of clear differences between diagnostic scans and scans intended for therapeutic management. The use of CT in radiation therapy planning is discussed and illustrated. MR imaging adds another dimension to treatment planning. The ability to use MR imaging directly in treatment planning involves an additional complex set of capabilities from a treatment planning system. The ability to unwarp the geometrically distorted MR image is a first step. Three-dimensional dose calculations are important to display the dose on sagittal and acoronal sections. The ability to integrate the MR and CT images into a unified radiographic image is critical. CT and MR images are two-dimensional representations of a three-dimensional problem. Through sophisticated computer graphics techniques, radiation therapists are now able to integrate a three-dimensional image of the patient into the treatment planning process. This allows the use of noncoplanar treatment plans and a detailed analysis of tumor and normal tissue anatomy; it is the first step toward a fully conformational treatment planning system. These concepts are illustrated and future research goals outlined

  9. Three-dimensional simulation of super-radiant Smith-Purcell radiation

    International Nuclear Information System (INIS)

    Li, D.; Imasaki, K.; Yang, Z.; Park, Gun-Sik

    2006-01-01

    A simulation of coherent and super-radiant Smith-Purcell radiation is performed in the gigahertz regime using a three-dimensional particle-in-cell code. The simulation model supposes a rectangular grating to be driven by a single electron bunch and a train of periodic bunches, respectively. The true Smith-Purcell radiation is distinguished from the evanescent wave, which has an angle independent frequency lower than the minimum allowed Smith-Purcell frequency. We also find that the super-radiant radiations excited by periodic bunches are emitted at higher harmonics of the bunching frequency and at the corresponding Smith-Purcell angles

  10. Radiative transfer calculations of the diffuse ionized gas in disc galaxies with cosmic ray feedback

    Science.gov (United States)

    Vandenbroucke, Bert; Wood, Kenneth; Girichidis, Philipp; Hill, Alex S.; Peters, Thomas

    2018-05-01

    The large vertical scale heights of the diffuse ionized gas (DIG) in disc galaxies are challenging to model, as hydrodynamical models including only thermal feedback seem to be unable to support gas at these heights. In this paper, we use a three-dimensional Monte Carlo radiation transfer code to post-process disc simulations of the Simulating the Life-Cycle of Molecular Clouds project that include feedback by cosmic rays. We show that the more extended discs in simulations including cosmic ray feedback naturally lead to larger scale heights for the DIG which are more in line with observed scale heights. We also show that including a fiducial cosmic ray heating term in our model can help to increase the temperature as a function of disc scale height, but fails to reproduce observed DIG nitrogen and sulphur forbidden line intensities. We show that, to reproduce these line emissions, we require a heating mechanism that affects gas over a larger density range than is achieved by cosmic ray heating, which can be achieved by fine tuning the total luminosity of ionizing sources to get an appropriate ionizing spectrum as a function of scale height. This result sheds a new light on the relation between forbidden line emissions and temperature profiles for realistic DIG gas distributions.

  11. New three-dimensional moving field radiation therapy for brain tumors

    Energy Technology Data Exchange (ETDEWEB)

    Mitsuyama, Fuyuki; Kanno, Tetsuo; Nagata, Yutaka; Koga, Sukehiko [Fujita-Gakuen Health Univ., Toyoake, Aichi (Japan); Jain, V K

    1992-06-01

    A new modified rotation radiation method called 'three-dimensional moving field radiation therapy' is described. The new method uses rotation in many planes while maintaining the same isocenter to achieve a good spatial dose distribution. This delivers a high dose to tumors and spares the surrounding normal structures. This easy method can be carried out using the equipment for conventional rotation radiation therapy. The new method was superior to the one plane rotation radiation therapy using a physical phantom with film, a chemical phantom using the iodine-starch reaction, and a new biological model using tumor cells. Treatment of six brain tumors irradiated with total air doses of 50-60 Gy caused no hair loss or radiation necrosis. (author).

  12. Treatment of primany hepatic carcinoma with three-dimensional conformal radiation therapy combined with transcatheter arterial chemoembolization

    International Nuclear Information System (INIS)

    Wu Li; Wen Xiaoping; Huang Wei

    2006-01-01

    Objective: To evaluate the effects of three-dimensional conformal radiation therapy (3DCRT) combined with transcatheter arterial chemoembolization (TACE) on stage m/IV primary hepatic carcinoma. Methods: Eighty cases of stage III/IV primary hepatic carcinoma were randomly divided into two groups: 40 cases treated with three-dimensional conformal radiation therapy combined with transcatheter arterial chemoembolization (3DCRT + TACE group) and 40 cases treated with three-dimensional conformal radiation therapy associated with hepatic arterial infusion chemotherapy (3DCRT +HAI group). Results: The response rates were 75% and 45% in 3DCRT + TACE group and 3DCRT + HAI group, respectively; and the difference between the two groups was statistically significant (P 0.05), The 0.5-, 1- and 2-year survival rates were 73% , 45% and 28% in 3DCRT + TACE group, and 45%, 25% and 13% in 3DCRT + HAI group, respectively; and the difference between the two groups was statistically significant (P 0.05). Conclusion: Three-dimensional conformal radiation therapy combined with transcatheter arterial chemoembolization improved prognosis of stage III/IV primary hepatic carcinoma. (authors)

  13. Biomedical applications of two- and three-dimensional deterministic radiation transport methods

    International Nuclear Information System (INIS)

    Nigg, D.W.

    1992-01-01

    Multidimensional deterministic radiation transport methods are routinely used in support of the Boron Neutron Capture Therapy (BNCT) Program at the Idaho National Engineering Laboratory (INEL). Typical applications of two-dimensional discrete-ordinates methods include neutron filter design, as well as phantom dosimetry. The epithermal-neutron filter for BNCT that is currently available at the Brookhaven Medical Research Reactor (BMRR) was designed using such methods. Good agreement between calculated and measured neutron fluxes was observed for this filter. Three-dimensional discrete-ordinates calculations are used routinely for dose-distribution calculations in three-dimensional phantoms placed in the BMRR beam, as well as for treatment planning verification for live canine subjects. Again, good agreement between calculated and measured neutron fluxes and dose levels is obtained

  14. Extending generalized Kubelka-Munk to three-dimensional radiative transfer.

    Science.gov (United States)

    Sandoval, Christopher; Kim, Arnold D

    2015-08-10

    The generalized Kubelka-Munk (gKM) approximation is a linear transformation of the double spherical harmonics of order one (DP1) approximation of the radiative transfer equation. Here, we extend the gKM approximation to study problems in three-dimensional radiative transfer. In particular, we derive the gKM approximation for the problem of collimated beam propagation and scattering in a plane-parallel slab composed of a uniform absorbing and scattering medium. The result is an 8×8 system of partial differential equations that is much easier to solve than the radiative transfer equation. We compare the solutions of the gKM approximation with Monte Carlo simulations of the radiative transfer equation to identify the range of validity for this approximation. We find that the gKM approximation is accurate for isotropic scattering media that are sufficiently thick and much less accurate for anisotropic, forward-peaked scattering media.

  15. Advantages of three-dimensional treatment planning in radiation therapy

    International Nuclear Information System (INIS)

    Attalla, E.M.; ELSAyed, A.A.; ElGantiry, M.; ElTahher, Z.

    2003-01-01

    This study was designed to demonstrate the feasibility of three-dimensional (3-D) treatment planning in-patients maxilla, breast, bladder, and lung tumors to explore its potential therapeutic advantage over the traditional dimensional (2-D) approach in these diseases. Conventional two-dimensional (2-D) treatment planning was compared to three-dimensional (3-D) treatment planning. In five selected disease sites, plans calculated with both types of treatment planning were compared. The (3-D) treatment planning system used in this work TMS version 5.1 B from helax AB is based on a monte Carlo-based pencil beam model. The other treatment planning system (2-D 0, introduced in this study was the multi data treatment planning system version 2.35. For the volumes of interest; quality of dose distribution concerning homogeneity in the target volume and the isodose distribution in organs at risk, was discussed. Qualitative and quantitative comparisons between the two planning systems were made using dose volume histograms (DVH's) . For comparisons of dose distributions in real-patient cases, differences ranged from 0.8% to 6.4% for 6 MV, while in case of 18 MV photon, it ranged from 1,8% to 6.5% and was within -+3 standard deviations for the dose between the two planning systems.Dose volume histogram (DVH) shows volume reduction of the radiation-related organs at risk 3-D planning

  16. Simulation of radiation effects on three-dimensional computer optical memories

    Science.gov (United States)

    Moscovitch, M.; Emfietzoglou, D.

    1997-01-01

    A model was developed to simulate the effects of heavy charged-particle (HCP) radiation on the information stored in three-dimensional computer optical memories. The model is based on (i) the HCP track radial dose distribution, (ii) the spatial and temporal distribution of temperature in the track, (iii) the matrix-specific radiation-induced changes that will affect the response, and (iv) the kinetics of transition of photochromic molecules from the colored to the colorless isomeric form (bit flip). It is shown that information stored in a volume of several nanometers radius around the particle's track axis may be lost. The magnitude of the effect is dependent on the particle's track structure.

  17. The three-dimension model for the rock-breaking mechanism of disc cutter and analysis of rock-breaking forces

    Science.gov (United States)

    Zhang, Zhao-Huang; Sun, Fei

    2012-06-01

    To study the rock deformation with three-dimensional model under rolling forces of disc cutter, by carrying out the circular-grooving test with disc cutter rolling around on the rock, the rock mechanical behavior under rolling disc cutter is studied, the mechanical model of disc cutter rolling around the groove is established, and the theory of single-point and double-angle variables is proposed. Based on this theory, the physics equations and geometric equations of rock mechanical behavior under disc cutters of tunnel boring machine (TBM) are studied, and then the balance equations of interactive forces between disc cutter and rock are established. Accordingly, formulas about normal force, rolling force and side force of a disc cutter are derived, and their validity is studied by tests. Therefore, a new method and theory is proposed to study rock-breaking mechanism of disc cutters.

  18. Measurement of the three-dimensional distribution of radiation dose in grid therapy

    International Nuclear Information System (INIS)

    Trapp, J V; Warrington, A P; Partridge, M; Philps, A; Glees, J; Tait, D; Ahmed, R; Leach, M O; Webb, S

    2004-01-01

    A single large dose of megavoltage x-rays delivered through a grid is currently being utilized by some centres for palliative radiotherapy treatments of large tumours. In this note, we investigate the dosimetry of grid therapy using two-dimensional film dosimetry and three-dimensional gel dosimetry. It is shown that the radiation dose is attenuated more rapidly with depth in a grid field than an open field, and that even shielded regions receive approximately 25% of the dose to the unshielded areas. (note)

  19. Simulation of radiation effects on three-dimensional computer optical memories

    International Nuclear Information System (INIS)

    Moscovitch, M.; Emfietzoglou, D.

    1997-01-01

    A model was developed to simulate the effects of heavy charged-particle (HCP) radiation on the information stored in three-dimensional computer optical memories. The model is based on (i) the HCP track radial dose distribution, (ii) the spatial and temporal distribution of temperature in the track, (iii) the matrix-specific radiation-induced changes that will affect the response, and (iv) the kinetics of transition of photochromic molecules from the colored to the colorless isomeric form (bit flip). It is shown that information stored in a volume of several nanometers radius around the particle close-quote s track axis may be lost. The magnitude of the effect is dependent on the particle close-quote s track structure. copyright 1997 American Institute of Physics

  20. Ho:YAG laser: intervertebral disk cell interaction using three-dimensional cell culture system

    Science.gov (United States)

    Sato, Masato; Ishihara, Miya; Arai, Tsunenori; Asazuma, Takashi; Kikuchi, Toshiyuki; Kikuchi, Makoto; Fujikawa, Kyosuke

    2000-06-01

    The purpose of this study is to evaluate the influence on the intervertebral disc cells after laser irradiation using three- dimensional culture system and to clarify the optimum Ho:YAG laser irradiation condition on percutaneous laser disc decompression (PLDD) for lumbar disc herniation. Since the Ho:YAG laser ablation is characterized by water-vapor bubble dynamics, not only thermal effect but also acoustic effect on cell metabolism might occur in the intervertebral disc. We studied the disc cell reaction from the metabolic point of view to investigate photothermal and photoacoustic effects on three-dimensional cultured disc cell. Intervertebral discs were obtained from female 30 Japanese white rabbits weighing about 1 kg. A pulsed Ho:YAG laser (wavelength: 2.1 micrometer, pulse width: about 200 microseconds) was delivered through a 200 micrometer-core diameter single silica glass fiber. We used the Ho:YAG laser irradiation fluence ranging from 60 to approximately 800 J/cm2 at the fiber end. To investigate acoustic effect, the acoustic transducer constructed with polyvinylidene fluoride (PVdF) film and acoustic absorber was used to detect the stress wave. Thermocouple and thermography were used to investigate thermal effect. Concerning damage of plasma membrane and ability of matrix synthesis, thermal effect might mainly affect cell reaction in total energy of 54 J (closed to practically used condition), but in 27 J, acoustic effect might contribute to it. We found that total energy was key parameter among the optimum condition, so that temperature and/or stress wave may influence Ho:YAG laser-disc cell interactions.

  1. Progress of radiotherapy by three-dimensional treatment planning

    International Nuclear Information System (INIS)

    Imada, Hajime; Nomoto, Satoshi; Takahashi, Hiroyuki; Nakata, Hajime

    1998-01-01

    The recent progress of three-dimensional radiation treatment planning was reviewed. And clinical cases such as lung cancer and breast cancer are introduced. In the University of Occupational and Development Health, the treatment system FOCUS which is made up of CT simulator and linac was used mainly. Three-dimensional treatment planning was carried for about 90% of 330 patients who underwent radiotherapy for one year. The target becomes to be accurate and dose distribution with all CT slices in radiation field can be confirmed by using three-dimensional radiation treatment planning apparatus. High dose irradiation localized to tumor part is possible. Relations between total dose and volume of normal tissue and/or tumor can be estimated numerically and easily by DVH. A prediction of indication and affection became possible by this procedure. In conclusion, generalization of three-dimensional radiation treatment planning will bring progress of more effective radiotherapy with less adverse reaction. (K.H.). 21 refs

  2. Anisotropic scattering in three dimensional differential approximation of radiation heat transfer

    International Nuclear Information System (INIS)

    Condiff, D.W.

    1987-01-01

    The differential approximation is extended to account for anisotropic scattering in invariant three dimensional form. A moment method using polyadic Legendre functions establishes that pressure cross sections should take precedence over extinction cross sections for treating radiation heat transfer in an absorbing, emitting, and scattering medium, and that use of these cross sections accounts for the extent of preferred forward or backwards scattering. The procedure and principle is extended to polyadic P-N approximations

  3. A three-dimensional model of solar radiation transfer in a non-uniform plant canopy

    Science.gov (United States)

    Levashova, N. T.; Mukhartova, Yu V.

    2018-01-01

    A three-dimensional (3D) model of solar radiation transfer in a non-uniform plant canopy was developed. It is based on radiative transfer equations and a so-called turbid medium assumption. The model takes into account the multiple scattering contributions of plant elements in radiation fluxes. These enable more accurate descriptions of plant canopy reflectance and transmission in different spectral bands. The model was applied to assess the effects of plant canopy heterogeneity on solar radiation transmission and to quantify the difference in a radiation transfer between photosynthetically active radiation PAR (=0.39-0.72 μm) and near infrared solar radiation NIR (Δλ = 0.72-3.00 μm). Comparisons of the radiative transfer fluxes simulated by the 3D model within a plant canopy consisted of sparsely planted fruit trees (plant area index, PAI - 0.96 m2 m-2) with radiation fluxes simulated by a one-dimensional (1D) approach, assumed horizontal homogeneity of plant and leaf area distributions, showed that, for sunny weather conditions with a high solar elevation angle, an application of a simplified 1D approach can result in an underestimation of transmitted solar radiation by about 22% for PAR, and by about 26% for NIR.

  4. Three-Dimensional Elasticity Solutions for Sound Radiation of Functionally Graded Materials Plates considering State Space Method

    Directory of Open Access Journals (Sweden)

    Tieliang Yang

    2016-01-01

    Full Text Available This paper presents an analytical study for sound radiation of functionally graded materials (FGM plate based on the three-dimensional theory of elasticity. The FGM plate is a mixture of metal and ceramic, and its material properties are assumed to have smooth and continuous variation in the thickness direction according to a power-law distribution in terms of volume fractions of the constituents. Based on the three-dimensional theory of elasticity and state space method, the governing equations with variable coefficients of the FGM plate are derived. The sound radiation of the vibration plate is calculated with Rayleigh integral. Comparisons of the present results with those of solutions in the available literature are made and good agreements are achieved. Finally, some parametric studies are carried out to investigate the sound radiation properties of FGM plates.

  5. Super-Cavitating Flow Around Two-Dimensional Conical, Spherical, Disc and Stepped Disc Cavitators

    Science.gov (United States)

    Sooraj, S.; Chandrasekharan, Vaishakh; Robson, Rony S.; Bhanu Prakash, S.

    2017-08-01

    A super-cavitating object is a high speed submerged object that is designed to initiate a cavitation bubble at the nose which extends past the aft end of the object, substantially reducing the skin friction drag that would be present if the sides of the object were in contact with the liquid in which the object is submerged. By reducing the drag force the thermal energy consumption to move faster can also be minimised. The super-cavitation behavioural changes with respect to Cavitators of various geometries have been studied by varying the inlet velocity. Two-dimensional computational fluid dynamics analysis has been carried out by applying k-ε turbulence model. The variation of drag coefficient, cavity length with respect to cavitation number and inlet velocity are analyzed. Results showed conical Cavitator with wedge angle of 30° has lesser drag coefficient and cavity length when compared to conical Cavitators with wedge angles 45° and 60°, spherical, disc and stepped disc Cavitators. Conical cavitator 60° and disc cavitator have the maximum cavity length but with higher drag coefficient. Also there is significant variation of supercavitation effect observed between inlet velocities of 32 m/s to 40 m/s.

  6. Rings and gaps in the disc around Elias 24 revealed by ALMA

    Science.gov (United States)

    Dipierro, G.; Ricci, L.; Pérez, L.; Lodato, G.; Alexander, R. D.; Laibe, G.; Andrews, S.; Carpenter, J. M.; Chandler, C. J.; Greaves, J. A.; Hall, C.; Henning, T.; Kwon, W.; Linz, H.; Mundy, L.; Sargent, A.; Tazzari, M.; Testi, L.; Wilner, D.

    2018-04-01

    We present Atacama Large Millimeter/sub-millimeter Array (ALMA) Cycle 2 observations of the 1.3-mm dust continuum emission of the protoplanetary disc surrounding the T Tauri star Elias 24 with an angular resolution of ˜0.2 arcsec (˜28 au). The dust continuum emission map reveals a dark ring at a radial distance of 0.47 arcsec (˜65 au) from the central star, surrounded by a bright ring at 0.58 arcsec (˜81 au). In the outer disc, the radial intensity profile shows two inflection points at 0.71 and 0.87 arcsec (˜99 and 121 au, respectively). We perform global three-dimensional smoothed particle hydrodynamic gas/dust simulations of discs hosting a migrating and accreting planet. Combining the dust density maps of small and large grains with three-dimensional radiative transfer calculations, we produce synthetic ALMA observations of a variety of disc models in order to reproduce the gap- and ring-like features observed in Elias 24. We find that the dust emission across the disc is consistent with the presence of an embedded planet with a mass of ˜0.7 MJ at an orbital radius of ˜ 60 au. Our model suggests that the two inflection points in the radial intensity profile are due to the inward radial motion of large dust grains from the outer disc. The surface brightness map of our disc model provides a reasonable match to the gap- and ring-like structures observed in Elias 24, with an average discrepancy of ˜5 per cent of the observed fluxes around the gap region.

  7. The therapeutic effect of three-dimensional conformal radiation therapy combined with conventional radiotherapy for nasopharyngeal carcinoma

    International Nuclear Information System (INIS)

    Liang Feng; Lu Zhonghong; Yao Zhijun; Cao Yongzhen

    2011-01-01

    Objective: To observe the therapeutic effect of three-dimensional conformal radiation therapy (3DCRT) for nasopharyngeal carcinoma (NPC). Methods: 78 patients with NPC was treated by radiation schedule in two phases. In the first phase, nasopharyngeal lesions and metastases of all patients were treated by three-dimensional conformal radiation therapy (3DCRT) with a fraction of 2-5 Gy daily, 5 day per weeks, total dose 30 Gy. The second phase T1N0 or parts of T2N0 patients were done by Conventional radiotherapy with total dose 55 Gy on two small lateral opposing fields + with total dose 50 Gy on neck on tangential field,adding a 3 cm block. Patients with lymph node metastasis were given 55 Gy on the dacio-neck field (After 40 Gy, two small lateral opposing fields were used to boost the primary tumor while the spinal cord shielded) + with total dose 55 Gy on lower neck on tangential field. The upper bound of designed therapeutic field was set to connect with lower bound of main therapeutic field. Results: Three months after treatment,the rate of CR, PR, SD, PD were 38.5%, 55.1%, 5.1%, 1.3%, Total effective rate (CR+PR) were 93.6%. The 1-year, 2-year, 3-year and 5-year local-regional control rates were 92.3%, 88.5%, 78.2%, 70.5%.The 1-year, 2-year , 3-year and 5-year overall survival rate were 96.2%, 89.7%, 83.3%, 71.8%. Appearing early radiation response is well tolerated and no obviously mouth difficulties and cranial nerve damage observed. Conclusion: Clinical result of early-course three-dimensional conformal radiation therapy (3DCRT) for nasopharyngeal carcinoma (NPC) is good. (authors)

  8. Three dimensional conformal radiation therapy may improve the therapeutic ratio of radiation therapy after pneumonectomy for lung cancer

    Energy Technology Data Exchange (ETDEWEB)

    Trouette, R; Causse, N; Elkhadri, M; Caudry, M; Maire, J P; Houlard, J P; Racaldini, L; Demeaux, H

    1995-12-01

    Three dimensional conformal radiation therapy would allow to decrease the normal tissue dose while maintaining the same target dose as standard treatment. To evaluate the feasibility of normal tissue dose reduction for ten patients with pneumonectomy for lung cancer, we determined the dose distribution to the normal tissue with 3-dimensional conformal radiation therapy (3-DCRT) and conventional treatment planning (CTP). Dose-volume histograms for target and normal tissue (lung, heart) were used for comparison of the different treatment planning. The mean percentages of lung and heart volumes which received 40 Gy with 3-DCRT were respectively 63% and 37% of the mean percentage of lung and volumes which received the same dose with CTP. These preliminary results suggest that conformal therapy may improve the therapeutic ratio by reducing risk to normal tissue.

  9. A numerical study of three-dimensional flame propagation over thin solids in purely forced concurrent flow including gas-phase radiation

    Science.gov (United States)

    Feier, Ioan I., Jr.

    The effect of flame radiation on concurrent-flow flame spread over a thin solid sample of finite width in a low-speed wind tunnel is modeled using three-dimensional full Navier-Stokes equations and three-dimensional flame radiation transfer equations. The formulation includes the conservation of mass, momentum, energy, and species: fuel vapor, oxygen, carbon dioxide and water vapor. The SN discrete ordinates method is used to solve the radiation transfer equation with a mean absorption coefficient kappa = Ckappa p, where kappap is the Planck mean absorption coefficient of the gas mixture. The varying parameter C has a value between 0 and 1; C represents the strength of flame radiation. In addition, the solid fuel absorptivity alpha is varied to ascertain the effect of flame radiation heat feedback to the solid. The flow tunnel modeled has a dimension of 10x10x30 cm, the solid fuel has a width of 6-cm with two 1-cm inert strips as edges. Incoming forced flow velocity (5 cm/s) of 21% oxygen is assumed. For comparison with the three-dimensional results, corresponding two-dimensional computations are also performed. Detailed spatial flame profiles, solid surface profiles, and heat fluxes are presented. Increasing the flame radiation strength decreases the flame length. Although flame radiation provides an additional heat transfer mechanism to preheat the solid, it is insufficient to offset the decreased convective heating due to the shorter flame; the net effect is a slower spread rate. The percentage of unreacted fuel vapor that escapes from the flame is under 2%. It is theorized that some of the pyrolyzed fuel vapor diffuses sideway and reacts at the flame edges. A radiative energy balance is analyzed also. Flame radiative feedback to the solid plays a more important role in two-dimensional flames. With high solid fuel absorptivity, a peak in the flame spread rate occurs at an intermediate value of flame radiation strength---due to the competition between two

  10. IPRT polarized radiative transfer model intercomparison project - Three-dimensional test cases (phase B)

    Science.gov (United States)

    Emde, Claudia; Barlakas, Vasileios; Cornet, Céline; Evans, Frank; Wang, Zhen; Labonotte, Laurent C.; Macke, Andreas; Mayer, Bernhard; Wendisch, Manfred

    2018-04-01

    Initially unpolarized solar radiation becomes polarized by scattering in the Earth's atmosphere. In particular molecular scattering (Rayleigh scattering) polarizes electromagnetic radiation, but also scattering of radiation at aerosols, cloud droplets (Mie scattering) and ice crystals polarizes. Each atmospheric constituent produces a characteristic polarization signal, thus spectro-polarimetric measurements are frequently employed for remote sensing of aerosol and cloud properties. Retrieval algorithms require efficient radiative transfer models. Usually, these apply the plane-parallel approximation (PPA), assuming that the atmosphere consists of horizontally homogeneous layers. This allows to solve the vector radiative transfer equation (VRTE) efficiently. For remote sensing applications, the radiance is considered constant over the instantaneous field-of-view of the instrument and each sensor element is treated independently in plane-parallel approximation, neglecting horizontal radiation transport between adjacent pixels (Independent Pixel Approximation, IPA). In order to estimate the errors due to the IPA approximation, three-dimensional (3D) vector radiative transfer models are required. So far, only a few such models exist. Therefore, the International Polarized Radiative Transfer (IPRT) working group of the International Radiation Commission (IRC) has initiated a model intercomparison project in order to provide benchmark results for polarized radiative transfer. The group has already performed an intercomparison for one-dimensional (1D) multi-layer test cases [phase A, 1]. This paper presents the continuation of the intercomparison project (phase B) for 2D and 3D test cases: a step cloud, a cubic cloud, and a more realistic scenario including a 3D cloud field generated by a Large Eddy Simulation (LES) model and typical background aerosols. The commonly established benchmark results for 3D polarized radiative transfer are available at the IPRT website (http

  11. Comparison of radiation delivered by current diagnostic procedures for herniated disc

    International Nuclear Information System (INIS)

    Gasquet, C.; Drouineau, J.; Goubault, F.; Hurmic, A.; Lavigne, B.; Vandermarcq, P.

    1983-01-01

    Three methods are currently employed for the diagnosis of sciatica due to disc lesions: radiculography, spinal phlebography, and computed tomography. Though their indications vary according to the author, it seemed worthwhile to compare radiation delivered by each of them, because of the often young age of the patients. Dosimetric studies using a Rando Phantom enabled calculation of doses to the skin, spinal cord, and gonads. Results indicated that low doses were delivered by the scanner, relatively high doses by spinal phlebography, and intermediate doses by radiculography. These findings suggest that the initial examination preoperatively in cases of simple sciatica due to herniated disc should be a CT scan whenever possible. Phlebography, on the contrary, and particularly in young women, should be used only exceptionally, as a result of the high doses delivered to the ovaries even during technically simple explorations [fr

  12. Magnetohydrodynamic three-dimensional flow of viscoelastic nanofluid in the presence of nonlinear thermal radiation

    Energy Technology Data Exchange (ETDEWEB)

    Hayat, T. [Department of Mathematics, Quaid-I-Azam University 45320, Islamabad 44000 (Pakistan); Nonlinear Analysis and Applied Mathematics (NAAM) Research Group, Faculty of Science, King Abdulaziz University, P. O. Box 80203, Jeddah 21589 (Saudi Arabia); Muhammad, Taseer, E-mail: taseer_qau@yahoo.com [Department of Mathematics, Quaid-I-Azam University 45320, Islamabad 44000 (Pakistan); Alsaedi, A.; Alhuthali, M.S. [Nonlinear Analysis and Applied Mathematics (NAAM) Research Group, Faculty of Science, King Abdulaziz University, P. O. Box 80203, Jeddah 21589 (Saudi Arabia)

    2015-07-01

    Magnetohydrodynamic (MHD) three-dimensional flow of couple stress nanofluid in the presence of thermophoresis and Brownian motion effects is analyzed. Energy equation subject to nonlinear thermal radiation is taken into account. The flow is generated by a bidirectional stretching surface. Fluid is electrically conducting in the presence of a constant applied magnetic field. The induced magnetic field is neglected for a small magnetic Reynolds number. Mathematical formulation is performed using boundary layer analysis. Newly proposed boundary condition requiring zero nanoparticle mass flux is employed. The governing nonlinear mathematical problems are first converted into dimensionless expressions and then solved for the series solutions of velocities, temperature and nanoparticles concentration. Convergence of the constructed solutions is verified. Effects of emerging parameters on the temperature and nanoparticles concentration are plotted and discussed. Skin friction coefficients and Nusselt number are also computed and analyzed. It is found that the thermal boundary layer thickness is an increasing function of radiative effect. - Highlights: • Three-dimensional boundary layer flow of viscoelastic nanofluid is examined. • Nonlinear thermal radiation is analyzed. • Brownian motion and thermophoresis effects are present. • Recently developed condition requiring zero nanoparticle mass flux is implemented. • Construction of convergent solutions of nonlinear flow is possible.

  13. Three-dimensional reconstruction and visualization system for medical images

    International Nuclear Information System (INIS)

    Preston, D.F.; Batnitzky, S.; Kyo Rak Lee; Cook, P.N.; Cook, L.T.; Dwyer, S.J.

    1982-01-01

    A three-dimensional reconstruction and visualization system could be of significant advantage in medical application such as neurosurgery and radiation treatment planning. The reconstructed anatomic structures from CT head scans could be used in a head stereotactic system to help plan the surgical procedure and the radiation treatment for a brain lesion. Also, the use of three-dimensional reconstruction algorithm provides for quantitative measures such as volume and surface area estimation of the anatomic features. This aspect of the three-dimensional reconstruction system may be used to monitor the progress or staging of a disease and the effects of patient treatment. Two cases are presented to illustrate the three-dimensional surface reconstruction and visualization system

  14. Three-dimensional imaging utilizing energy discrimination

    International Nuclear Information System (INIS)

    Gunter, D.L.; Hoffman, K.R.; Beck, R.N.

    1990-01-01

    An algorithm is proposed for three-dimensional image reconstruction in nuclear medicine which uses scattered radiation rather than multiple projected images to determine the source depth within the body. Images taken from numerous energy windows are combined to construct the source distribution in the body. The gamma-ray camera is not moved during the imaging process. Experiments with both Tc-99m and Ga-67 demonstrate that two channels of depth information can be extracted from the low energy images produced by scattered radiation. By combining this technique with standard SPECT reconstruction using multiple projections the authors anticipate much improved spatial resolution in the overall three-dimensional reconstruction

  15. 71: Three dimensional radiation treatment planning system

    International Nuclear Information System (INIS)

    Purdy, J.A.; Wong, J.W.; Harms, W.B.; Drzymala, R.E.; Emami, B.

    1987-01-01

    A prototype 3-dimensional (3-D) radiation treatment planning (RTP) system has been developed and is in use. The system features a real-time display device and an array processor for computer intensive computations. The dose distribution can be displayed as 2-D isodose distributions superimposed on 2-D gray scale images of the patient's anatomy for any arbitrary plane and as a display of isodose surfaces in 3-D. In addition, dose-volume histograms can be generated. 7 refs.; 2 figs

  16. Thermally radiative three-dimensional flow of Jeffrey nanofluid with internal heat generation and magnetic field

    Energy Technology Data Exchange (ETDEWEB)

    Shehzad, S.A., E-mail: ali_qau70@yahoo.com [Department of Mathematics, Comsats Institute of Information Technology, Sahiwal 57000 (Pakistan); Abdullah, Z. [Department of Mathematics, Comsats Institute of Information Technology, Sahiwal 57000 (Pakistan); Alsaedi, A. [Nonlinear Analysis and Applied Mathematics (NAAM) Research Group, Faculty of Science, King Abdulaziz University, P. O. Box 80257, Jeddah 21589 (Saudi Arabia); Abbasi, F.M. [Department of Mathematics, Comsats Institute of Information Technology, Islamabad 44000 (Pakistan); Hayat, T. [Nonlinear Analysis and Applied Mathematics (NAAM) Research Group, Faculty of Science, King Abdulaziz University, P. O. Box 80257, Jeddah 21589 (Saudi Arabia); Department of Mathematics, Quaid-I-Azam University 45320, Islamabad 44000 (Pakistan)

    2016-01-01

    This research work addresses the three-dimensional hydromagnetic flow of Jeffrey fluid with nanoparticles. Flow is generated by a bidirectional stretching surface. The effects of thermal radiation and internal heat generation are encountered in energy expressions. More realistic convective boundary conditions at the surface are employed instead of constant surface temperature and mass species conditions. Boundary layer assumptions lead to the governing non-linear mathematical model. Resulting equations through momentum, energy and mass species are made dimensionless using suitable variables. The solution expressions of dimensionless velocities, temperature and nanoparticle concentration have been computed for the convergent series solutions. The impacts of interesting parameters on the dimensionless quantities are displayed and interpreted. The values of physical quantities are computed and analyzed. - Highlights: • Three-dimensional hydromagnetic flow of Jeffrey nanofluid is considered. • Brownian motion and thermophoresis effects are encountered. • Heat transfer analysis is performed with thermal radiation. • Results are plotted and visualized.

  17. Three-dimensional radiative transfer in an isotropically scattering, plane-parallel medium: generalized X- and Y-functions

    International Nuclear Information System (INIS)

    Mueller, D.W.; Crosbie, A.L.

    2005-01-01

    The topic of this work is the generalized X- and Y-functions of multidimensional radiative transfer. The physical problem considered is spatially varying, collimated radiation incident on the upper boundary of an isotropically scattering, plane-parallel medium. An integral transform is used to reduce the three-dimensional transport equation to a one-dimensional form, and a modified Ambarzumian's method is used to derive coupled, integro-differential equations for the source functions at the boundaries of the medium. The resulting equations are said to be in double-integral form because the integration is over both angular variables. Numerical results are presented to illustrate the computational characteristics of the formulation

  18. Three-dimensional conformal radiation therapy: the tomo-therapy approach

    International Nuclear Information System (INIS)

    Linthout, N.; Verellen, D.; Coninck, P. de; Bel, A.; Storme, G.

    2000-01-01

    Conformal radiation therapy allows the possibility of delivering high doses at the tumor volume whilst limiting the dose to the surrounding tissues and diminishing the secondary effects. With the example of the conformal radiation therapy used at the AZ VU8 (3DCRT and tomo-therapy), two treatment plans of a left ethmoid carcinoma will be evaluated and discussed in detail. The treatment of ethmoid cancer is technically difficult for both radiation therapy and surgery because of the anatomic constraints and patterns of local spread. A radiation therapy is scheduled to be delivered after surgical resection of the tumor. The treatment plan for the radiation therapy was calculated on a three-dimensional (3D) treatment planning system based on virtual simulation with a beam's eye view: George Sherouse's Gratis. An effort was made to make the plan as conformal and as homogeneous as possible to deliver a dose of 66 Gy in 33 fractions at the tumor bed with a maximum dose of 56 Gy to the right optic nerve and the chiasma. To establish the clinical utility and potential advantages of tomo-therapy over 3DCRT for ethmoid carcinoma, the treatment of this patient was also planned with Peacock Plant. For both treatment plans the isodose distributions and cumulative dose volume histograms (CDVH) were computed. Superimposing the CDVHs yielded similar curves for the target and an obvious improvement for organs at risk such as the chiasma, brainstem and the left eye when applying tomo-therapy. These results have also been reflected in the tumor control probabilities (equal for both plans) and the normal tissue complication probabilities (NTCP), yielding significant reductions in NTCP for tomo-therapy. The probability of uncomplicated tumor control was 52.7% for tomo-therapy against 38.3% for 3DCRT. (authors)

  19. A simplified description of the three-dimensional structure of agroforestry trees for use with a radiative transfer model

    International Nuclear Information System (INIS)

    Meloni, S.

    1998-01-01

    To simulate transmitted radiation in agroforestry systems, radiative transfer models usually require a detailed three-dimensional description of the tree canopy. We propose here a simplification of the description of the three-dimensional structure of wild cherry trees (Prunus avium). The simplified tree description was tested against the detailed one for five-year-old wild cherry. It allowed accurate simulation of transmitted radiation and avoided tedious measurements of tree structure. The simplified description was then applied to older trees. Allometric relationships were used to compute the parameters not available on free-grown trees. The transmitted radiation in an agroforestry system was simulated at four different ages: 5, 10, 15 and 20 years. The trees were planted on a 5 m square grid. Two row orientations, chosen to provide different transmitted radiation patterns, were tested: north/south and north- east/south-west. The simulations showed that the daily mean transmitted radiation was reduced from 92% of incident radiation under five-year-old trees to 37% under 20-year-old trees. The variability of transmitted radiation increased with tree growth. The row orientation had only small effects on the shaded area at the beginning and end of the day when solar elevation was low. (author)

  20. Superluminous accretion discs

    Energy Technology Data Exchange (ETDEWEB)

    Sikora, M [Cambridge Univ. (UK). Inst. of Astronomy; Polska Akademia Nauk, Warsaw. Centrum Astronomiczne)

    1981-07-01

    Upper limits are computed for the total luminosities and collimation of radiation from thick, radiation supported accretion discs around black holes. Numerical results are obtained for the 'extreme' discs with rsub(out) = 10/sup 3/ GMsub(BH)/c/sup 2/, the angular momentum of the black hole being Jsub(BH) = 0.998 GMsub(BH)/c. The high luminosity (L approximately 8.5 Lsub(Edd)) and substantial collimation of radiation found for these discs indicate that such discs can explain both the high luminosities of quasars and similar objects and may produce some of the observed beams and jets.

  1. Graphic system for the analysis of representation of a complex three-dimensional configuration for radiation shield calculation

    International Nuclear Information System (INIS)

    Berezhkov, A.B.; Gordeeva, E.K.; Mazanov, V.L.; Solov'ev, V.Yu.; Ryabov, A.V.; Khokhlov, V.F.; Shejno, I.N.

    1987-01-01

    Programs for obtaining phantom images when calculating the radiation shield structure for nuclear-engineering plants, using computer graphics, are developed. Programs are designed to accompany calculational investigations using the SUPER2/RRI3-PICSCH program and ZAMOK-TOMOGRAF program comutering complexes. Design geometry techniques, allowing to present three-dimensional object in the form of two-dimensional perspective projection to the screen plane, are realized in the programs

  2. An three-dimensional imaging algorithm based on the radiation model of electric dipole

    International Nuclear Information System (INIS)

    Tian Bo; Zhong Weijun; Tong Chuangming

    2011-01-01

    A three-dimensional imaging algorithm based on the radiation model of dipole (DBP) is presented. On the foundation of researching the principle of the back projection (BP) algorithm, the relationship between the near field imaging model and far field imaging model is analyzed based on the scattering model. Firstly, the far field sampling data is transferred to the near field sampling data through applying the radiation theory of dipole. Then the dealt sampling data was projected to the imaging region to obtain the images of targets. The capability of the new algorithm to detect targets is verified by using finite-difference time-domain method (FDTD), and the coupling effect for imaging is analyzed. (authors)

  3. Hawking radiation of spin-1 particles from a three-dimensional rotating hairy black hole

    Energy Technology Data Exchange (ETDEWEB)

    Sakalli, I.; Ovgun, A., E-mail: ali.ovgun@emu.edu.tr [Eastern Mediterranean University Famagusta, North Cyprus, Department of Physics (Turkey)

    2015-09-15

    We study the Hawking radiation of spin-1 particles (so-called vector particles) from a three-dimensional rotating black hole with scalar hair using a Hamilton–Jacobi ansatz. Using the Proca equation in the WKB approximation, we obtain the tunneling spectrum of vector particles. We recover the standard Hawking temperature corresponding to the emission of these particles from a rotating black hole with scalar hair.

  4. Three dimensional conformal radiation therapy in pediatric parameningeal rhabdomyosarcomas

    International Nuclear Information System (INIS)

    Michalski, Jeff M.; Harms, William B.; Purdy, James A.; Sur, Ranjan K.

    1995-01-01

    Purpose: We evaluated the utility of three dimensional (3D) treatment planning in the management of children with parameningeal head and neck rhabdomyosarcomas. Methods and Materials: Five children with parameningeal rhabdomyosarcoma were referred for treatment at our radiation oncology center from May 1990 through January 1993. Each patient was evaluated, staged, and treated according to the Intergroup Rhabdomyosarcoma Study. Patients were immobilized and underwent a computed tomography scan with contrast in the treatment position. Tumor and normal tissues were identified with assistance from a diagnostic radiologist and defined in each slice. The patients were then planned and treated with the assistance of a 3D treatment planning system. A second plan was then devised by another physician without the benefit of the 3D volumetric display. The target volumes designed with the 3D system and the two-dimensional (2D) method were then compared. The dosimetric coverage to tumor, tumor plus margin, and normal tissues was also compared with the two methods of treatment planning. Results: The apparent size of the gross tumor volume was underestimated with the conventional 2D planning method relative to the 3D method. When margin was added around the gross tumor to account for microscopic extension of disease in the 2D method, the expected area of coverage improved relative to the 3D method. In each circumstance, the minimum dose that covered the gross tumor was substantially less with the 2D method than with the 3D method. The inadequate dosimetric coverage was especially pronounced when the necessary margin to account for subclinical disease was added. In each case, the 2D plans would have delivered substantial dose to adjacent normal tissues and organs, resulting in a higher incidence of significant complications. Conclusions: 3D conformal radiation therapy has a demonstrated advantage in the treatment of sarcomas of the head and neck. The improved dosimetric coverage

  5. Three-dimensional modeling of radiative and convective exchanges in the urban atmosphere

    International Nuclear Information System (INIS)

    Qu, Yongfeng

    2011-01-01

    In many micro-meteorological studies, building resolving models usually assume a neutral atmosphere. Nevertheless, urban radiative transfers play an important role because of their influence on the energy budget. In order to take into account atmospheric radiation and the thermal effects of the buildings in simulations of atmospheric flow and pollutant dispersion in urban areas, we have developed a three-dimensional (3D) atmospheric radiative scheme, in the atmospheric module of the Computational Fluid Dynamics model Code-Saturne. The radiative scheme was previously validated with idealized cases, using as a first step, a constant 3D wind field. In this work, the full coupling of the radiative and thermal schemes with the dynamical model is evaluated. The aim of the first part is to validate the full coupling with the measurements of the simple geometry from the 'Mock Urban Setting Test' (MUST) experiment. The second part discusses two different approaches to model the radiative exchanges in urban area with a comparison between Code-Saturne and SOLENE. The third part applies the full coupling scheme to show the contribution of the radiative transfer model on the airflow pattern in low wind speed conditions in a 3D urban canopy. In the last part we use the radiative-dynamics coupling to simulate a real urban environment and validate the modeling approach with field measurements from the 'Canopy and Aerosol Particles Interactions in Toulouse Urban Layer' (CAPITOUL). (author) [fr

  6. Stress distribution in the temporo-mandibular joint discs during jaw closing: a high-resolution three-dimensional finite-element model analysis.

    Science.gov (United States)

    Savoldelli, Charles; Bouchard, Pierre-Olivier; Loudad, Raounak; Baque, Patrick; Tillier, Yannick

    2012-07-01

    This study aims at analysing the stresses distribution in the temporomandibular joint (TMJ) using a complete high-resolution finite element model (FE Model). This model is used here to analyse the stresses distribution in the discs during a closing jaw cycle. In the end, this model enables the prediction of the stress evolution in the TMJ disc submitted to various loadings induced by mandibular trauma, surgery or parafunction. The geometric data for the model were obtained from MRI and CT scans images of a healthy male patient. Surface and volume meshes were successively obtained using a 3D image segmentation software (AMIRA(®)). Bone components of skull and mandible, both of joint discs, temporomandibular capsules and ligaments and dental arches were meshed as separate bodies. The volume meshes were transferred to the FE analysis software (FORGE(®)). Material properties were assigned for each region. Boundary conditions for closing jaw simulations were represented by different load directions of jaws muscles. The von Mises stresses distribution in both joint discs during closing conditions was analyzed. The pattern of von Mises stresses in the TMJ discs is non-symmetric and changed continuously during jaw movement. Maximal stress is reached on the surface disc in areas in contact with others bodies. The three-dimension finite element model of masticatory system will make it possible to simulate different conditions that appear to be important in the cascade of events leading to joint damage.

  7. Observability of planet-disc interactions in CO kinematics

    Science.gov (United States)

    Pérez, Sebastián; Casassus, S.; Benítez-Llambay, P.

    2018-06-01

    Empirical evidence of planets in gas-rich circumstellar discs is required to constrain giant planet formation theories. Here we study the kinematic patterns which arise from planet-disc interactions and their observability in CO rotational emission lines. We perform three-dimensional hydrodynamical simulations of single giant planets, and predict the emergent intensity field with radiative transfer. Pressure gradients at planet-carved gaps, spiral wakes and vortices bear strong kinematic counterparts. The iso-velocity contours in the CO(2-1) line centroids vo reveal large-scale perturbations, corresponding to abrupt transitions from below sub-Keplerian to super-Keplerian rotation along with radial and vertical flows. The increase in line optical depth at the edge of the gap also modulates vo, but this is a mild effect compared to the dynamical imprint of the planet-disc interaction. The large-scale deviations from the Keplerian rotation thus allow the planets to be indirectly detected via the first moment maps of molecular gas tracers, at ALMA angular resolutions. The strength of these deviations depends on the mass of the perturber. This initial study paves the way to eventually determine the mass of the planet by comparison with more detailed models.

  8. A three-dimensional radiation image display on a real space image created via photogrammetry

    Science.gov (United States)

    Sato, Y.; Ozawa, S.; Tanifuji, Y.; Torii, T.

    2018-03-01

    The Fukushima Daiichi Nuclear Power Station (FDNPS), operated by Tokyo Electric Power Company Holdings, Inc., went into meltdown after the occurrence of a large tsunami caused by the Great East Japan Earthquake of March 11, 2011. The radiation distribution measurements inside the FDNPS buildings are indispensable to execute decommissioning tasks in the reactor buildings. We have developed a three-dimensional (3D) image reconstruction method for radioactive substances using a compact Compton camera. Moreover, we succeeded in visually recognizing the position of radioactive substances in real space by the integration of 3D radiation images and the 3D photo-model created using photogrammetry.

  9. Reconstruction of mechanically recorded sound from an edison cylinder using three dimensional non-contact optical surface metrology

    Energy Technology Data Exchange (ETDEWEB)

    Fadeyev, V.; Haber, C.; Maul, C.; McBride, J.W.; Golden, M.

    2004-04-20

    Audio information stored in the undulations of grooves in a medium such as a phonograph disc record or cylinder may be reconstructed, without contact, by measuring the groove shape using precision optical metrology methods and digital image processing. The viability of this approach was recently demonstrated on a 78 rpm shellac disc using two dimensional image acquisition and analysis methods. The present work reports the first three dimensional reconstruction of mechanically recorded sound. The source material, a celluloid cylinder, was scanned using color coded confocal microscopy techniques and resulted in a faithful playback of the recorded information.

  10. [Research advances of three-dimension printing technology in vertebrae and intervertebral disc tissue engineering].

    Science.gov (United States)

    Yang, Zechuan; Li, Chunde; Sun, Haolin

    2016-03-01

    Three-dimensional (3D) printing technology is characterized by "inside-out" stack manufacturing. Compared with conventional technologies, 3D printing has the advantage of personalization and precision. Therefore, the shape and internal structure of the scaffolds made by 3D printing technology are highly biomimetic. Besides, 3D bioprinting can precisely deposit the biomaterials, seeding cells and cytokines at the same time, which is a breakthrough in printing technique and material science. With the development of 3D printing, it will make great contributions to the reconstruction of vertebrae and intervertebral disc in the future.

  11. [Three dimensional finite element model of a modified posterior cervical single open-door laminoplasty].

    Science.gov (United States)

    Wang, Q; Yang, Y; Fei, Q; Li, D; Li, J J; Meng, H; Su, N; Fan, Z H; Wang, B Q

    2017-06-06

    Objective: To build a three-dimensional finite element models of a modified posterior cervical single open-door laminoplasty with short-segmental lateral mass screws fusion. Methods: The C(2)-C(7) segmental data were obtained from computed tomography (CT) scans of a male patient with cervical spondylotic myelopathy and spinal stenosis.Three-dimensional finite element models of a modified cervical single open-door laminoplasty (before and after surgery) were constructed by the combination of software package MIMICS, Geomagic and ABAQUS.The models were composed of bony vertebrae, articulating facets, intervertebral disc and associated ligaments.The loads of moments 1.5Nm at different directions (flexion, extension, lateral bending and axial rotation)were applied at preoperative model to calculate intersegmental ranges of motion.The results were compared with the previous studies to verify the validation of the models. Results: Three-dimensional finite element models of the modified cervical single open- door laminoplasty had 102258 elements (preoperative model) and 161 892 elements (postoperative model) respectively, including C(2-7) six bony vertebraes, C(2-3)-C(6-7) five intervertebral disc, main ligaments and lateral mass screws.The intersegmental responses at the preoperative model under the loads of moments 1.5 Nm at different directions were similar to the previous published data. Conclusion: Three-dimensional finite element models of the modified cervical single open- door laminoplasty were successfully established and had a good biological fidelity, which can be used for further study.

  12. Comparison of efficacy of three commercially available antibiotic discs

    Directory of Open Access Journals (Sweden)

    Joshi A

    2008-01-01

    Full Text Available A study was undertaken to evaluate the efficacy of commercially available antimicrobial discs manufactured by Oxoid, UK, HiMedia Laboratories, Mumbai and Span Diagnostics, Surat. The discs were evaluated for their performance on the basis of percentage of coefficient of variation (%CV which is a measure of reproducibility, mean zone diameters which is a measure of accuracy and range of zone diameter using both standard ATCC strains and clinical isolates. The data showed variation for all three manufacturers and therefore routine and regular quality control of discs as well as meticulous following of good laboratory practices is strongly advocated in clinical laboratories

  13. Three-dimensional culture conditions lead to decreased radiation induced cytotoxicity in human mammary epithelial cells

    International Nuclear Information System (INIS)

    Sowa, Marianne B.; Chrisler, William B.; Zens, Kyra D.; Ashjian, Emily J.; Opresko, Lee K.

    2010-01-01

    For both targeted and non-targeted exposures, the cellular responses to ionizing radiation have predominantly been measured in two-dimensional monolayer cultures. Although convenient for biochemical analysis, the true interactions in vivo depend upon complex interactions between cells themselves and the surrounding extracellular matrix. This study directly compares the influence of culture conditions on radiation induced cytotoxicity following exposure to low-LET ionizing radiation. Using a three-dimensional (3D) human mammary epithelial tissue model, we have found a protective effect of 3D cell culture on cell survival after irradiation. The initial state of the cells (i.e., 2D versus 3D culture) at the time of irradiation does not alter survival, nor does the presence of extracellular matrix during and after exposure to dose, but long term culture in 3D which offers significant reduction in cytotoxicity at a given dose (e.g. ∼4-fold increased survival at 5 Gy). The cell cycle delay induced following exposure to 2 and 5 Gy was almost identical between 2D and 3D culture conditions and cannot account for the observed differences in radiation responses. However the amount of apoptosis following radiation exposure is significantly decreased in 3D culture relative to the 2D monolayer after the same dose. A likely mechanism of the cytoprotective effect afforded by 3D culture conditions is the down regulation of radiation induced apoptosis in 3D structures.

  14. A three-dimensional phase space dynamical model of the Earth's radiation belt

    International Nuclear Information System (INIS)

    Boscher, D. M.; Beutier, T.; Bourdarie, S.

    1996-01-01

    A three dimensional phase space model of the Earth's radiation belt is presented. We have taken into account the magnetic and electric radial diffusions, the pitch angle diffusions due to Coulomb interactions and interactions with the plasmaspheric hiss, and the Coulomb drag. First, a steady state of the belt is presented. Two main maxima are obtained, corresponding to the inner and outer parts of the belt. Then, we have modelled a simple injection at the external boundary. The particle transport seems like what was measured aboard satellites. A high energy particle loss is found, by comparing the model results and the measurements. It remains to be explained

  15. The impact of the artificial intervertebral disc on functioning the lumbar spine

    Directory of Open Access Journals (Sweden)

    Mańsko M.

    2015-12-01

    Full Text Available In the hereby thesis the anatomy of the lumbar vertebra and intervertebral disc were presented. Functioning and kinematics of the spine and intervertebral forces were described.Full threedimensional model of the lumbar vertebrae L2 – L4 was created. On the basis of it model of artificial intervertebral disc was constructed (between L2 and L3. The simplified model of vertebra L2 was formulated via finite elements method. Processed model has been used for biomechanical analysis.Strength calculations were made and appropriate conclusions were drawn. Presented results show behavior influenced of threedimensional model of the lumbar vertebra with artificial intervertebral disc by operation of loads.

  16. Three-dimensional evaluation of lumbar disc hernia and prediction of absorption by enhanced MRI

    International Nuclear Information System (INIS)

    Kawaji, Youichi; Uchiyama, Seiji; Yagi, Eiichi

    2001-01-01

    Both the spontaneous shrinkage and the disappearance of disc hernia have been confirmed through the use of computed tomography (CT) and magnetic resonance imaging (MRI). There is, however, no practical method to predict the likely absorption of the herniated mass. The objective of this study was to predict the spontaneous absorption of disc hernia by MRI, and to select the optimum treatment. The study involved 65 patients with lumbar disc hernias. Conservative treatment was carried out in 21 patients, while 44 patients underwent herniotomy. In the nonoperated patients, an MRI was taken both during the painful period, and shortly after pain remission. Hernial shrinkage was evaluated according to the decrease in the calculated volume, in addition to the decrease in hernial area, calculated by MRI. In the operated group, preoperative MRI enhancement, type of hernia, and invasion of granulation tissue in the histological specimens were studied. In the 21 nonoperated patients, the volume (mean ±SD) was 0.488±208 cm 3 (range, 0.197-0.931 cm 3 ) in the painful period and 0.214±0.181 cm 3 (range, 0.0-0.744 cm 3 ) in the remission period. This decrease in volume was statistically significant. There was also a greater decrease in hernias exhibiting positive enhancement by MRI. In the operated patients, hernias that penetrated the posterior longitudinal ligament (PLL) had high rates of preoperative enhancement, and these hernias showed invasion of granulation tissue with marked neovascularization. Positive enhancement by MRI confirms an ongoing absorption process. Enhanced MRI can be a good method for the prediction of spontaneous absorption of lumbar disc hernias. (author)

  17. Three-dimensional evaluation of lumbar disc hernia and prediction of absorption by enhanced MRI

    Energy Technology Data Exchange (ETDEWEB)

    Kawaji, Youichi; Uchiyama, Seiji [Niigata Univ. (Japan). School of Medicine; Yagi, Eiichi

    2001-07-01

    Both the spontaneous shrinkage and the disappearance of disc hernia have been confirmed through the use of computed tomography (CT) and magnetic resonance imaging (MRI). There is, however, no practical method to predict the likely absorption of the herniated mass. The objective of this study was to predict the spontaneous absorption of disc hernia by MRI, and to select the optimum treatment. The study involved 65 patients with lumbar disc hernias. Conservative treatment was carried out in 21 patients, while 44 patients underwent herniotomy. In the nonoperated patients, an MRI was taken both during the painful period, and shortly after pain remission. Hernial shrinkage was evaluated according to the decrease in the calculated volume, in addition to the decrease in hernial area, calculated by MRI. In the operated group, preoperative MRI enhancement, type of hernia, and invasion of granulation tissue in the histological specimens were studied. In the 21 nonoperated patients, the volume (mean {+-}SD) was 0.488{+-}208 cm{sup 3} (range, 0.197-0.931 cm{sup 3}) in the painful period and 0.214{+-}0.181 cm{sup 3} (range, 0.0-0.744 cm{sup 3}) in the remission period. This decrease in volume was statistically significant. There was also a greater decrease in hernias exhibiting positive enhancement by MRI. In the operated patients, hernias that penetrated the posterior longitudinal ligament (PLL) had high rates of preoperative enhancement, and these hernias showed invasion of granulation tissue with marked neovascularization. Positive enhancement by MRI confirms an ongoing absorption process. Enhanced MRI can be a good method for the prediction of spontaneous absorption of lumbar disc hernias. (author)

  18. Three dimensional analysis of planar solid oxide fuel cell stack considering radiation

    Energy Technology Data Exchange (ETDEWEB)

    Tanaka, T.; Inui, Y.; Urata, A.; Kanno, T. [Department of Electrical and Electronic Engineering, Toyohashi University of Technology, Tempaku-cho, Toyohashi 441-8580 (Japan)

    2007-05-15

    The authors have been engaged in numerical simulations of the planar type solid oxide fuel cell (SOFC) to make clear the dependence of the cell performance on its operating conditions. Up to now, the authors have already developed the simulation codes for the one channel region and the single cell plate in its cell stack. To calculate accurately the effect of radiation heat transfer from the cell stack surfaces, however, a code that can treat the whole cell stack is necessary. In the present study, therefore, the authors newly develop a three dimensional simulation code of the planar SOFC stack, and the detailed effect of the radiation heat transfer is investigated. It is made clear that the conventional codes are sufficiently accurate, and the newly developed whole cell stack code is not inevitable to predict the maximum cell temperature. This is because the thermal conductivity of the cell materials made of ceramics is very small, and the central part of the cell stack is almost free from the influence of radiation heat transfer. On the other hand, the stack simulation is needed to calculate accurately the cell voltage because the radiation heat transfer reduces it when the ambient temperature is low. The bad influence of low ambient temperature on the voltage is, however, small and relatively high voltage is obtained even when the ambient temperature is very low. (author)

  19. Three-Dimensional Printing of Drug-Eluting Implants

    DEFF Research Database (Denmark)

    Water, Jorrit Jeroen; Bohr, Adam; Bøtker, Johan Peter

    2015-01-01

    The aim of the present work was to investigate the potential of three-dimensional (3D) printing as a manufacturing method for products intended for personalized treatments by exploring the production of novel polylactide-based feedstock materials for 3D printing purposes. Nitrofurantoin (NF......) and hydroxyapatite (HA) were successfully mixed and extruded with up to 30% drug load with and without addition of 5% HA in polylactide strands, which were subsequently 3D-printed into model disc geometries (10 × 2 mm). X-ray powder diffraction analysis showed that NF maintained its anhydrate solid form during...... of custom-made, drug-loaded feedstock materials for 3D printing of pharmaceutical products for controlled release....

  20. Radiation Dosimetry Using Three-Dimensional Optical Random Access Memories

    International Nuclear Information System (INIS)

    Moscovitch, M.

    2001-01-01

    The ability to determine particle type and energy plays an important role in the dosimetry of heavy charged particles (HCP) and neutrons. A new approach to radiation dosimetry is presented, which is shown to be capable of particle type and energy discrimination. This method is based on utilizing radiation induced changes in the digital information stored on three-dimensional optical random access memories (3D ORAM). 3D ORAM is a small cube (a few mm 3 ) composed of poly(methyl methacrylate) doped with a photochromic dye, and it was originally proposed as a memory device in high speed parallel computers. A Nd:YAG laser system is used to write and read binary information (bits) on the ORAM, which functions as a charged particle detector. Both the read and the write processes use two laser beams that simultaneously strike the material to cause a color change at their intersection (similar to the darkening of light-sensitive sunglasses when exposed to sunlight.) The laser produces color changes in the ORAM, which then reverts to the original color (''bit-flips'') at sites where energy is deposited from interaction with incident HCP or neutron-recoil protons. The feasibility of this approach was demonstrated both theoretically and experimentally. Calculations based on track structure theory (TST) predict that when HCP interact with the ORAM material, the local energy deposition is capable of inducing measurable ''bit-flips''. These predictions were recently confirmed experimentally using two types of ORAM systems, one based on spirobenzopyran and the other on anthracene, as the photochromic dyes

  1. Radiation dosimetry using three-dimensional optical random access memories

    International Nuclear Information System (INIS)

    Moscovitch, M.; Phillips, G.W.; Cullum, B.M.; Mobley, J.; Bogard, J.S.; Emfietzoglou, D.; Vo-Dinh, T.

    2002-01-01

    The ability to determine particle type and energy plays an important role in the dosimetry of heavy charged particles (HCP) and neutrons. A new approach to radiation dosimetry is presented, which is shown to be capable of particle type and energy discrimination. This method is based on utilising radiation induced changes in the digital information stored on three-dimensional optical random access memories (3D ORAM). 3D ORAM is a small cube (a few mm 3 ) composed of poly(methyl methacrylate) doped with a photochromic dye, and it was originally proposed as a memory device in high speed parallel computers. A Nd:YAG laser system is used to write and read binary information (bits) on the ORAM, which functions as a charged particle detector. Both the read and the write processes use two laser beams that simultaneously strike the material to cause a colour change at their intersection (similar to the darkening of light-sensitive sunglasses when exposed to sunlight). The laser produces colour changes in the ORAM, which then reverts to the original colour ('bit-flips') at sites where energy is deposited from interaction with incident HCP or neutron-recoil protons. The feasibility of this approach was demonstrated both theoretically and experimentally. Calculations based on track structure theory predict that when HCP interact with the ORAM material, the local energy deposition is capable of inducing measurable 'bit-flips'. These predictions were recently confirmed experimentally using two types of ORAM systems, one based on spirobenzopyran and the other on anthracene, as the photochromic dyes. (author)

  2. Evaluation of solar energy over three dimensional objects

    International Nuclear Information System (INIS)

    Serposhan, S.; Yaghoubi, M.

    2002-01-01

    The knowledge of solar irradiation is important in heating and cooling of buildings architectural engineering, various solar energy utilizations, and for any system design exposed to sun radiation. In the present article, simulation is made to predict solar irradiation over any three-dimensional objects. Special consideration is made to evaluate solar radiation intensity distribution over semi-circular roof and domed roofs. For practical applications, hourly and average daily solar radiation distribution for a series of three Heller type huge cooling towers of Fars Power Plant is also determined

  3. Dose response study of PVA-Fx gel for three dimensional dose distribution

    International Nuclear Information System (INIS)

    Brindha, S.; Ayyangar, Komanduri M.; Shen, Bin; Saw, Cheng B.

    2001-01-01

    Modern radiotherapy techniques involve complex field arrangements using conformal and intensity modulated radiation that requires three dimensional treatment planning. The verification of these plans poses even more challenge. In 1984, Gore et al., proposed that ferrous gel dosimeters combined with magnetic resonance imaging (MRI) could be used to measure three dimensional radiation dose distributions. Since then, there has been much interest in the development of gel dosimetry to aid the determination of three dimensional dose distributions during field arrangements. In this work, preparation and study of the MR characteristics of a PVA-Fx gel reported in the literature is presented

  4. Diffraction limited focusing with controllable arbitrary three-dimensional polarization

    International Nuclear Information System (INIS)

    Chen, Weibin; Zhan, Qiwen

    2010-01-01

    We propose a new approach that enables full control over the three-dimensional state of polarization and the field distribution near the focus of a high numerical aperture objective lens. By combining the electric dipole radiation and a vectorial diffraction method, the input field at the pupil plane for generating arbitrary three-dimensionally oriented linear polarization at the focal point with a diffraction limited spot size is found analytically by solving the inverse problem. Arbitrary three-dimensional elliptical polarization can be obtained by introducing a second electric dipole oriented in the orthogonal plane with appropriate amplitude and phase differences

  5. Implementation of three dimensional conformal radiation therapy: prospects, opportunities, and challenges

    International Nuclear Information System (INIS)

    Vijayakumar, Srinivasan; Chen, George T.Y.

    1995-01-01

    Purpose: To briefly review scientific rationale of 3D conformal radiation therapy (3DCRT) and discuss the prospects, opportunities, and challenges in the implementation of 3DCRT. Some of these ideas were discussed during a workshop on 'Implementation of Three-Dimensional Conformal Radiation Therapy' in April 1994 at Bethesda, MD, and others have been discussed elsewhere in the literature. Methods and Materials: Local-regional control of cancer is an important component in the overall treatment strategy in any patient with cancer. It has been shown that failure to achieve local-regional control can lead to (a) an increase in chances of distant metastases, and (b) a decrease in the survival. In many disease sites, the doses delivered currently are inadequate to achieve satisfactory local tumor control rates; this is because in many sites, only limited doses of radiotherapy can be delivered due to the proximity of cancer to radiosensitive normal tissues. By conforming the radiotherapy beams to the tumor, doses to the tumors can be enhanced and doses to the normal tissues can be reduced. With the advances in 3DCRT, such conformation is possible now and is the rationale for using 3DCRT. However, a number of questions do remain that are not limited to the following: (a) What are the implications in terms of target volume definitions when implementing 3DCRT? (b) Are there some sites where research efforts can be focused to document the efficacy and cost effectiveness of 3DCRT? (c) How do we implement day-to-day 3DCRT treatment efficiently? (d) How do we transfer the technology from the university centers to the community without compromising quality? (e) What are all the quality assurance/quality improvement questions that need to be addressed and how do we ascertain quality assurance of 3DCRT? (f) Have we looked at cost-benefit ratios and quality of life (QOL) issues closely? Results: There is a need for defining multiple target volumes: gross tumor volume, clinical

  6. Three-dimensional Einstein-Klein-Gordon system in characteristic numerical relativity

    International Nuclear Information System (INIS)

    Barreto, W.; Silva, A. da; Lehner, L.; Gomez, R.; Rosales, L.; Winicour, J.

    2005-01-01

    We incorporate a massless scalar field into a three-dimensional code for the characteristic evolution of the gravitational field. The extended three-dimensional code for the Einstein-Klein-Gordon system is calibrated to be second-order convergent. It provides an accurate calculation of the gravitational and scalar radiation at infinity. As an application, we simulate the fully nonlinear evolution of an asymmetric scalar pulse of ingoing radiation propagating toward an interior Schwarzschild black hole and compute the backscattered scalar and gravitational outgoing radiation patterns. The amplitudes of the scalar and gravitational outgoing radiation modes exhibit the predicted power law scaling with respect to the amplitude of the initial data. For the scattering of an axisymmetric scalar field, the final ring down matches the complex frequency calculated perturbatively for the l=2 quasinormal mode

  7. A Global Three-Dimensional Radiation Hydrodynamic Simulation of a Self-Gravitating Accretion Disk

    Science.gov (United States)

    Phillipson, Rebecca; Vogeley, Michael S.; McMillan, Stephen; Boyd, Patricia

    2018-01-01

    We present three-dimensional, radiation hydrodynamic simulations of initially thin accretion disks with self-gravity using the grid-based code PLUTO. We produce simulated light curves and spectral energy distributions and compare to observational data of X-ray binary (XRB) and active galactic nuclei (AGN) variability. These simulations are of interest for modeling the role of radiation in accretion physics across decades of mass and frequency. In particular, the characteristics of the time variability in various bandwidths can probe the timescales over which different physical processes dominate the accretion flow. For example, in the case of some XRBs, superorbital periods much longer than the companion orbital period have been observed. Smoothed particle hydrodynamics (SPH) calculations have shown that irradiation-driven warping could be the mechanism underlying these long periods. In the case of AGN, irradiation-driven warping is also predicted to occur in addition to strong outflows originating from thermal and radiation pressure driving forces, which are important processes in understanding feedback and star formation in active galaxies. We compare our simulations to various toy models via traditional time series analysis of our synthetic and observed light curves.

  8. Relativistic three-dimensional Lippmann-Schwinger cross sections for space radiation applications

    Science.gov (United States)

    Werneth, C. M.; Xu, X.; Norman, R. B.; Maung, K. M.

    2017-12-01

    Radiation transport codes require accurate nuclear cross sections to compute particle fluences inside shielding materials. The Tripathi semi-empirical reaction cross section, which includes over 60 parameters tuned to nucleon-nucleus (NA) and nucleus-nucleus (AA) data, has been used in many of the world's best-known transport codes. Although this parameterization fits well to reaction cross section data, the predictive capability of any parameterization is questionable when it is used beyond the range of the data to which it was tuned. Using uncertainty analysis, it is shown that a relativistic three-dimensional Lippmann-Schwinger (LS3D) equation model based on Multiple Scattering Theory (MST) that uses 5 parameterizations-3 fundamental parameterizations to nucleon-nucleon (NN) data and 2 nuclear charge density parameterizations-predicts NA and AA reaction cross sections as well as the Tripathi cross section parameterization for reactions in which the kinetic energy of the projectile in the laboratory frame (TLab) is greater than 220 MeV/n. The relativistic LS3D model has the additional advantage of being able to predict highly accurate total and elastic cross sections. Consequently, it is recommended that the relativistic LS3D model be used for space radiation applications in which TLab > 220MeV /n .

  9. A retrospective and prospective survey of three-dimensional transport calculations

    International Nuclear Information System (INIS)

    Nakahara, Yasuaki

    1985-01-01

    A retrospective survey is made on the three-dimensional radiation transport calculations. Introduction is given to computer codes based on the distinctive numerical methods such as the Monte Carlo, Direct Integration, Ssub(n) and Finite Element Methods to solve the three-dimensional transport equations. Prospective discussions are made on pros and cons of these methods. (author)

  10. Australian and New Zealand three-dimensional conformal radiation therapy consensus guidelines for prostate cancer

    International Nuclear Information System (INIS)

    Skala, M.; Berry, M.; Kneebone, A.; Gogna, K.; Turner, S.; Rolfo, A.; Haworth, A.

    2004-01-01

    Three-dimensional conformal radiation therapy (3DCRT) has been shown to reduce normal tissue toxicity and allow dose escalation in the curative treatment of prostate cancer. The Faculty of Radiation Oncology Genito-Urinary Group initiated a consensus process to generate evidence-based guidelines for the safe and effective implementation of 3DCRT. All radiation oncology departments in Australia and New Zealand were invited to complete a survey of their prostate practice and to send representatives to a consensus workshop. After a review of the evidence, key issues were identified and debated. If agreement was not reached, working parties were formed to make recommendations. Draft guidelines were circulated to workshop participants for approval prior to publication. Where possible, evidence-based recommendations have been made with regard to patient selection, risk stratification, simulation, planning, treatment delivery and toxicity reporting. This is the first time a group of radiation therapists, physicists and oncologists representing professional radiotherapy practice across Australia and New Zealand have worked together to develop best-practice guidelines. These guidelines should serve as a baseline for prospective clinical trials, outcome research and quality assurance. Copyright (2004) Blackwell Science Pty Ltd

  11. Three dimensional illustrating - three-dimensional vision and deception of sensibility

    Directory of Open Access Journals (Sweden)

    Anita Gánóczy

    2009-03-01

    Full Text Available The wide-spread digital photography and computer use gave the opportunity for everyone to make three-dimensional pictures and to make them public. The new opportunities with three-dimensional techniques give chance for the birth of new artistic photographs. We present in detail the biological roots of three-dimensional visualization, the phenomena of movement parallax, which can be used efficiently in making three-dimensional graphics, the Zöllner- and Corridor-illusion. There are present in this paper the visual elements, which contribute to define a plane two-dimensional image in three-dimension: coherent lines, the covering, the measurement changes, the relative altitude state, the abatement of detail profusion, the shadings and the perspective effects of colors.

  12. Integrative shell of the program complex MARS (Version 1.0) radiation transfer in three-dimensional geometries

    International Nuclear Information System (INIS)

    Degtyarev, I.I.; Lokhovitskij, A.E.; Maslov, M.A.; Yazynin, I.A.

    1994-01-01

    The first version of integrative shell of the program complex MARS is written for calculating radiation transfer in the three-dimensional geometries. The integrative shell allows the user to work in convenient form with complex MARS, creat input files data and get graphic visualization of calculated functions. Version 1.0 is adapted for personal computers of types IBM-286,386,486 with operative size memory not smaller than 500K. 5 refs

  13. Development of a three-dimensional radiation dosimetry system

    International Nuclear Information System (INIS)

    Bero, M.A.

    2001-12-01

    The direct non-destructive measurement of the radiation absorbed dose in three dimensions is considered to be technically difficult. Accurate determination of the spatial distribution of absorbed dose plays an important role in many applications particularly in medicine. In radiotherapy computer calculations are frequently used to estimate three-dimensional dose distributions in complex geometry, hence a practical dosimetry system able to provide three-dimensional (3-D) integrated measurements is highly desirable for verifying such dose predictions. Magnetic Resonance Imaging (MRI) has been used to visualise 3-D dose distributions, inside two different detector materials, namely the ferrous sulphate gel (Fricke gel) and the polymer gel system. Each of these procedures has its own drawbacks and limitations, and this research project sought to find improvements and alternatives to overcome these problems. Work on the Fricke gel led to an improved preparation procedure employing gelatin gel whose lower melting point reduces the possibility of dissolved oxygen loss. The role of each component was clarified which led to the omission of all unnecessary chemicals such as the sodium chloride and benzoic acid. Initially MRI was the only 3-D readout technique available, however simple relaxometry was used to characterise the detector quantitatively with each modification before employing an MRI scanner to obtain images. Optimisation of the active constituents saves time and effort, and minimises the cost of equipment as well as materials. A serious drawback of the Fricke gel is ion diffusion, which causes blurring of the recorded spatial distribution and much effort was given to attempts to reduce this. However it was concluded that it is possible to slow down ion diffusion but at the cost of detector sensitivity. Therefore the best way of dealing with this problem is by introducing a fast readout technique so that the dose distribution can be recorded before serious

  14. Three-dimensional wave-induced current model equations and radiation stresses

    Science.gov (United States)

    Xia, Hua-yong

    2017-08-01

    After the approach by Mellor (2003, 2008), the present paper reports on a repeated effort to derive the equations for three-dimensional wave-induced current. Via the vertical momentum equation and a proper coordinate transformation, the phase-averaged wave dynamic pressure is well treated, and a continuous and depth-dependent radiation stress tensor, rather than the controversial delta Dirac function at the surface shown in Mellor (2008), is provided. Besides, a phase-averaged vertical momentum flux over a sloping bottom is introduced. All the inconsistencies in Mellor (2003, 2008), pointed out by Ardhuin et al. (2008) and Bennis and Ardhuin (2011), are overcome in the presently revised equations. In a test case with a sloping sea bed, as shown in Ardhuin et al. (2008), the wave-driving forces derived in the present equations are in good balance, and no spurious vertical circulation occurs outside the surf zone, indicating that Airy's wave theory and the approach of Mellor (2003, 2008) are applicable for the derivation of the wave-induced current model.

  15. Application of the three-dimensional transport code to analysis of the neutron streaming experiment

    International Nuclear Information System (INIS)

    Chatani, K.; Slater, C.O.

    1990-01-01

    The neutron streaming through an experimental mock-up of a Clinch River Breeder Reactor (CRBR) prototypic coolant pipe chaseway was recalculated with a three-dimensional discrete ordinates code. The experiment was conducted at the Tower Shielding Facility at Oak Ridge National Laboratory in 1976 and 1977. The measurement of the neutron flux, using Bonner ball detectors, indicated nine orders of attenuation in the empty pipeway, which contained two 90-deg bends and was surrounded by concrete walls. The measurement data were originally analyzed using the DOT3.5 two-dimensional discrete ordinates radiation transport code. However, the results did not agree with measurement data at the bend because of the difficulties in modeling the three-dimensional configurations using two-dimensional methods. The two-dimensional calculations used a three-step procedure in which each of the three legs making the two 90-deg bends was a separate calculation. The experiment was recently analyzed with the TORT three-dimensional discrete ordinates radiation transport code, not only to compare the calculational results with the experimental results, but also to compare with results obtained from analyses in Japan using DOT3.5, MORSE, and ENSEMBLE, which is a three-dimensional discrete ordinates radiation transport code developed in Japan

  16. Quantum tunneling from three-dimensional black holes

    International Nuclear Information System (INIS)

    Ejaz, Asiya; Gohar, H.; Lin, Hai; Saifullah, K.; Yau, Shing-Tung

    2013-01-01

    We study Hawking radiation from three-dimensional black holes. For this purpose the emission of charged scalar and charged fermionic particles is investigated from charged BTZ black holes, with and without rotation. We use the quantum tunneling approach incorporating WKB approximation and spacetime symmetries. Another class of black holes which is asymptotic to a Sol three-manifold has also been investigated. This procedure gives us the tunneling probability of outgoing particles, and we compute the temperature of the radiation for these black holes. We also consider the quantum tunneling of particles from black hole asymptotic to Sol geometry

  17. Beam simulation of synchrotron radiation equipment. New method responsive to three dimensional magnetic field

    International Nuclear Information System (INIS)

    Tanaka, Hirofumi

    1999-01-01

    A new numerical analysis method capable of precise modeling of complex three dimensional magnetic field of superconducting wiggler and of long-term beam simulation without destroying property of Hamiltonian dynamics system was developed by using the above-mentioned method. Therefore, a fundamental design of a compact synchrotron radiation equipment with hexagonal column shape was also developed. Its main parameters had 1 GeV in energy, 36 m in circumference, 300 mA in stored current, and 184 nmrad in emittance. So as to enable to research the x-ray and vacuum UV regions, a superconducting wiggler with 7T in magnetic field strength and an undulator were set at straight section. It depends upon if beam around stable region on exciting the superconducting wiggler is wider than the required region whether this type of synchrotron radiation equipment can be realized or not. By using three orbit analysis methods containing the developed one, the circulating stable region was introduced. As a result, although shape of the stable region was different from used methods, it was found that considerably larger stable region was obtained than the required in circulation results of every three methods. That is to say, it was shown that the designed compact equipment can accumulate electron beams stably. (G.K.)

  18. Three-dimensional teletherapy treatment planning

    International Nuclear Information System (INIS)

    Panthaleon van Eck, R.B. van.

    1986-01-01

    This thesis deals with physical/mathematical backgrounds of computerized teletherapy treatment planning. The subjects discussed in this thesis can be subdivided into three main categories: a) Three-dimensional treatment planning. A method is evaluated which can be used for the purpose of simulation and optimization of dose distributions in three dimensions. b) The use of Computed Tomography. The use of patient information obtained from Computed Tomography for the purpose of dose computations is evaluated. c) Dose computational models for photon- and electron beams. Models are evaluated which provide information regarding the way in which the radiation dose is distributed in the patient (viz. is absorbed and/or dispersed). (Auth.)

  19. Accelerated hypofractionated three-dimensional conformal radiation therapy in the treatment of non-small cell lung cancer

    International Nuclear Information System (INIS)

    Yu Jinming; Zheng Aiqing; Yu Yonghua; Wang Xuetao; Yuan Shuanghu; Han Dali; Li Kunhai

    2005-01-01

    Objective: To evaluate the effect and complication of non-small-cell lung cancer (NSCLC) treated with accelerated hypofractionated three dimensional conforms] radiation therapy (3DCRT). Methods: There were squamous carcinoma 21, adenocarcinoma 7, squamous-adenocarcinoma 4 and other cancer 3. There were 17 stage I and 18 stage II. Thirty-five patients of NSCLC were treated with a dose of 30-48 Gy in 6 or 8 Gy per fraction, 3 times a week. The outcome of these patients Was analyzed. Results: The overall 1-, 2- and 3- Year survival rate was 78.2%, 46.9% and 36.3%, respectively. The 1- and 2-year recurrence-free survival rate was 64.6 % and 39.7 %, respectively. The acute radiation pneumonitis and late lung fibrosis rates were high. Univariate analysis showed that Vm was a significant predictor of acute radiation pneumonitis. Conclusion: Compared with accelerated hypofractionated irradiation, the routine conventional fractionated radiation therapy may be preferred for more patients of NSCLC. (authors)

  20. Polycrystalline diamond detectors with three-dimensional electrodes

    Energy Technology Data Exchange (ETDEWEB)

    Lagomarsino, S., E-mail: lagomarsino@fi.infn.it [University of Florence, Department of Physics, Via Sansone 1, 50019 Sesto Fiorentino (Italy); INFN Firenze, Via B. Rossi 1, 50019 Sesto Fiorentino (Italy); Bellini, M. [INO-CNR Firenze, Largo E. Fermi 6, 50125 Firenze (Italy); Brianzi, M. [INFN Firenze, Via B. Rossi 1, 50019 Sesto Fiorentino (Italy); Carzino, R. [Smart Materials-Nanophysics, Istituto Italiano di Tecnologia, Genova, Via Morego 30, 16163 Genova (Italy); Cindro, V. [Joseph Stefan Institute, Jamova Cesta 39, 1000 Ljubljana (Slovenia); Corsi, C. [University of Florence, Department of Physics, Via Sansone 1, 50019 Sesto Fiorentino (Italy); LENS Firenze, Via N. Carrara 1, 50019 Sesto Fiorentino (Italy); Morozzi, A.; Passeri, D. [INFN Perugia, Perugia (Italy); Università degli Studi di Perugia, Dipartimento di Ingegneria, via G. Duranti 93, 06125 Perugia (Italy); Sciortino, S. [University of Florence, Department of Physics, Via Sansone 1, 50019 Sesto Fiorentino (Italy); INFN Firenze, Via B. Rossi 1, 50019 Sesto Fiorentino (Italy); Servoli, L. [INFN Perugia, Perugia (Italy)

    2015-10-01

    The three-dimensional concept in diamond detectors has been applied, so far, to high quality single-crystal material, in order to test this technology in the best available conditions. However, its application to polycrystalline chemical vapor deposited diamond could be desirable for two reasons: first, the short inter-electrode distance of three-dimensional detectors should improve the intrinsically lower collection efficiency of polycrystalline diamond, and second, at high levels of radiation damage the performances of the poly-crystal material are not expected to be much lower than those of the single crystal one. We report on the fabrication and test of three-dimensional polycrystalline diamond detectors with several inter-electrode distances, and we demonstrate that their collection efficiency is equal or higher than that obtained with conventional planar detectors fabricated with the same material. - Highlights: • Pulsed laser fabrication of polycristalline diamond detectors with 3D electrodes. • Measurement of the charge collection efficiency (CCE) under beta irradiation. • Comparation between the CCE of 3D and conventional planar diamond sensors. • A rationale for the behavior of three-dimensional and planar sensors is given.

  1. Method for coupling two-dimensional to three-dimensional discrete ordinates calculations

    International Nuclear Information System (INIS)

    Thompson, J.L.; Emmett, M.B.; Rhoades, W.A.; Dodds, H.L. Jr.

    1985-01-01

    A three-dimensional (3-D) discrete ordinates transport code, TORT, has been developed at the Oak Ridge National Laboratory for radiation penetration studies. It is not feasible to solve some 3-D penetration problems with TORT, such as a building located a large distance from a point source, because (a) the discretized 3-D problem is simply too big to fit on the computer or (b) the computing time (and corresponding cost) is prohibitive. Fortunately, such problems can be solved with a hybrid approach by coupling a two-dimensional (2-D) description of the point source, which is assumed to be azimuthally symmetric, to a 3-D description of the building, the region of interest. The purpose of this paper is to describe this hybrid methodology along with its implementation and evaluation in the DOTTOR (Discrete Ordinates to Three-dimensional Oak Ridge Transport) code

  2. Three-dimensional, position-sensitive radiation detection

    Science.gov (United States)

    He, Zhong; Zhang, Feng

    2010-04-06

    Disclosed herein is a method of determining a characteristic of radiation detected by a radiation detector via a multiple-pixel event having a plurality of radiation interactions. The method includes determining a cathode-to-anode signal ratio for a selected interaction of the plurality of radiation interactions based on electron drift time data for the selected interaction, and determining the radiation characteristic for the multiple-pixel event based on both the cathode-to-anode signal ratio and the electron drift time data. In some embodiments, the method further includes determining a correction factor for the radiation characteristic based on an interaction depth of the plurality of radiation interactions, a lateral distance between the selected interaction and a further interaction of the plurality of radiation interactions, and the lateral positioning of the plurality of radiation interactions.

  3. HEROIC: 3D general relativistic radiative post-processor with comptonization for black hole accretion discs

    Science.gov (United States)

    Narayan, Ramesh; Zhu, Yucong; Psaltis, Dimitrios; Saḑowski, Aleksander

    2016-03-01

    We describe Hybrid Evaluator for Radiative Objects Including Comptonization (HEROIC), an upgraded version of the relativistic radiative post-processor code HERO described in a previous paper, but which now Includes Comptonization. HEROIC models Comptonization via the Kompaneets equation, using a quadratic approximation for the source function in a short characteristics radiation solver. It employs a simple form of accelerated lambda iteration to handle regions of high scattering opacity. In addition to solving for the radiation field, HEROIC also solves for the gas temperature by applying the condition of radiative equilibrium. We present benchmarks and tests of the Comptonization module in HEROIC with simple 1D and 3D scattering problems. We also test the ability of the code to handle various relativistic effects using model atmospheres and accretion flows in a black hole space-time. We present two applications of HEROIC to general relativistic magnetohydrodynamics simulations of accretion discs. One application is to a thin accretion disc around a black hole. We find that the gas below the photosphere in the multidimensional HEROIC solution is nearly isothermal, quite different from previous solutions based on 1D plane parallel atmospheres. The second application is to a geometrically thick radiation-dominated accretion disc accreting at 11 times the Eddington rate. Here, the multidimensional HEROIC solution shows that, for observers who are on axis and look down the polar funnel, the isotropic equivalent luminosity could be more than 10 times the Eddington limit, even though the spectrum might still look thermal and show no signs of relativistic beaming.

  4. Carcinoma of the anal canal: Intensity modulated radiation therapy (IMRT) versus three-dimensional conformal radiation therapy (3DCRT)

    Science.gov (United States)

    Sale, Charlotte; Moloney, Phillip; Mathlum, Maitham

    2013-01-01

    Introduction Patients with anal canal carcinoma treated with standard conformal radiotherapy frequently experience severe acute and late toxicity reactions to the treatment area. Roohipour et al. (Dis Colon Rectum 2008; 51: 147–53) stated a patient's tolerance of chemoradiation to be an important prediction of treatment success. A new intensity modulated radiation therapy (IMRT) technique for anal carcinoma cases has been developed at the Andrew Love Cancer Centre aimed at reducing radiation to surrounding healthy tissue. Methods A same-subject repeated measures design was used for this study, where five anal carcinoma cases at the Andrew Love Cancer Centre were selected. Conformal and IMRT plans were generated and dosimetric evaluations were performed. Each plan was prescribed a total of 54 Gray (Gy) over a course of 30 fractions to the primary site. Results The IMRT plans resulted in improved dosimetry to the planning target volume (PTV) and reduction in radiation to the critical structures (bladder, external genitalia and femoral heads). Statistically there was no difference between the IMRT and conformal plans in the dose to the small and large bowel; however, the bowel IMRT dose–volume histogram (DVH) doses were consistently lower. Conclusion The IMRT plans were superior to the conformal plans with improved dose conformity and reduced radiation to the surrounding healthy tissue. Anecdotally it was found that patients tolerated the IMRT treatment better than the three-dimensional (3D) conformal radiation therapy. This study describes and compares the planning techniques. PMID:26229623

  5. Carcinoma of the anal canal: Intensity modulated radiation therapy (IMRT) versus three-dimensional conformal radiation therapy (3DCRT)

    International Nuclear Information System (INIS)

    Sale, Charlotte; Moloney, Phillip; Mathlum, Maitham

    2013-01-01

    Patients with anal canal carcinoma treated with standard conformal radiotherapy frequently experience severe acute and late toxicity reactions to the treatment area. Roohipour et al. (Dis Colon Rectum 2008; 51: 147–53) stated a patient's tolerance of chemoradiation to be an important prediction of treatment success. A new intensity modulated radiation therapy (IMRT) technique for anal carcinoma cases has been developed at the Andrew Love Cancer Centre aimed at reducing radiation to surrounding healthy tissue. A same-subject repeated measures design was used for this study, where five anal carcinoma cases at the Andrew Love Cancer Centre were selected. Conformal and IMRT plans were generated and dosimetric evaluations were performed. Each plan was prescribed a total of 54 Gray (Gy) over a course of 30 fractions to the primary site. The IMRT plans resulted in improved dosimetry to the planning target volume (PTV) and reduction in radiation to the critical structures (bladder, external genitalia and femoral heads). Statistically there was no difference between the IMRT and conformal plans in the dose to the small and large bowel; however, the bowel IMRT dose–volume histogram (DVH) doses were consistently lower. The IMRT plans were superior to the conformal plans with improved dose conformity and reduced radiation to the surrounding healthy tissue. Anecdotally it was found that patients tolerated the IMRT treatment better than the three-dimensional (3D) conformal radiation therapy. This study describes and compares the planning techniques

  6. Carcinoma of the anal canal: Intensity modulated radiation therapy (IMRT) versus three-dimensional conformal radiation therapy (3DCRT).

    Science.gov (United States)

    Sale, Charlotte; Moloney, Phillip; Mathlum, Maitham

    2013-12-01

    Patients with anal canal carcinoma treated with standard conformal radiotherapy frequently experience severe acute and late toxicity reactions to the treatment area. Roohipour et al. (Dis Colon Rectum 2008; 51: 147-53) stated a patient's tolerance of chemoradiation to be an important prediction of treatment success. A new intensity modulated radiation therapy (IMRT) technique for anal carcinoma cases has been developed at the Andrew Love Cancer Centre aimed at reducing radiation to surrounding healthy tissue. A same-subject repeated measures design was used for this study, where five anal carcinoma cases at the Andrew Love Cancer Centre were selected. Conformal and IMRT plans were generated and dosimetric evaluations were performed. Each plan was prescribed a total of 54 Gray (Gy) over a course of 30 fractions to the primary site. The IMRT plans resulted in improved dosimetry to the planning target volume (PTV) and reduction in radiation to the critical structures (bladder, external genitalia and femoral heads). Statistically there was no difference between the IMRT and conformal plans in the dose to the small and large bowel; however, the bowel IMRT dose-volume histogram (DVH) doses were consistently lower. The IMRT plans were superior to the conformal plans with improved dose conformity and reduced radiation to the surrounding healthy tissue. Anecdotally it was found that patients tolerated the IMRT treatment better than the three-dimensional (3D) conformal radiation therapy. This study describes and compares the planning techniques.

  7. Carcinoma of the anal canal: Intensity modulated radiation therapy (IMRT) versus three-dimensional conformal radiation therapy (3DCRT)

    Energy Technology Data Exchange (ETDEWEB)

    Sale, Charlotte; Moloney, Phillip; Mathlum, Maitham [Andrew Love Cancer Centre, Geelong Hospital, Geelong, Victoria (Australia)

    2013-12-15

    Patients with anal canal carcinoma treated with standard conformal radiotherapy frequently experience severe acute and late toxicity reactions to the treatment area. Roohipour et al. (Dis Colon Rectum 2008; 51: 147–53) stated a patient's tolerance of chemoradiation to be an important prediction of treatment success. A new intensity modulated radiation therapy (IMRT) technique for anal carcinoma cases has been developed at the Andrew Love Cancer Centre aimed at reducing radiation to surrounding healthy tissue. A same-subject repeated measures design was used for this study, where five anal carcinoma cases at the Andrew Love Cancer Centre were selected. Conformal and IMRT plans were generated and dosimetric evaluations were performed. Each plan was prescribed a total of 54 Gray (Gy) over a course of 30 fractions to the primary site. The IMRT plans resulted in improved dosimetry to the planning target volume (PTV) and reduction in radiation to the critical structures (bladder, external genitalia and femoral heads). Statistically there was no difference between the IMRT and conformal plans in the dose to the small and large bowel; however, the bowel IMRT dose–volume histogram (DVH) doses were consistently lower. The IMRT plans were superior to the conformal plans with improved dose conformity and reduced radiation to the surrounding healthy tissue. Anecdotally it was found that patients tolerated the IMRT treatment better than the three-dimensional (3D) conformal radiation therapy. This study describes and compares the planning techniques.

  8. CHANGE: A numerical model for three-dimensional modelling of channelized flow in rock: Theory and design

    International Nuclear Information System (INIS)

    Billaux, D.; Long, J.C.S.; Peterson, J.E. Jr.

    1990-03-01

    A model for channelized flow in three-dimensional, random networks of fractures has been developed. In this model, the fractures are disc-shaped discontinuities in an impermeable matrix. Within each fracture, flow occurs only in a network of random channels. The channels in each fracture can be generated independently with random distributions of length, conductivity, and orientation in the fracture plane. Boundary conditions are specified on the sides of a ''flow region,'' and at the intersections of the channels with interior ''holes'' specified by the user to simulate boreholes or drifts. This code is part of a set of programs used to generate two-dimensional or three-dimensional random fracture networks, plot them, compute flow through them and analyze the results. 8 refs., 13 figs

  9. Comparison of acute and subacute genitourinary and gastrointestinal adverse events of radiotherapy for prostate cancer using intensity-modulated radiation therapy, three-dimensional conformal radiation therapy, permanent implant brachytherapy and high-dose-rate brachytherapy

    NARCIS (Netherlands)

    Morimoto, Masahiro; Yoshioka, Yasuo; Konishi, Koji; Isohashi, Fumiaki; Takahashi, Yutaka; Ogata, Toshiyuki; Koizumi, Masahiko; Teshima, Teruki; Bijl, Henk P; van der Schaaf, Arjen; Langendijk, Johannes A; Ogawa, Kazuhiko

    2014-01-01

    AIMS AND BACKGROUND: To examine acute and subacute urinary and rectal toxicity in patients with localized prostate cancer monotherapeutically treated with the following four radiotherapeutic techniques: intensity-modulated radiation therapy, three-dimensional conformal radiation therapy,

  10. Modellierung dreidimensionaler Strahlungsfelder im frühen Universum %t Modelling three dimensional radiation fields in the early universe

    Science.gov (United States)

    Meinköhn, Erik

    2002-11-01

    The present work aims at the modelling of three-dimensional radiation fields in gas clouds from the early universe, in particular as to the influence of varying distributions of density and velocity. In observations of high-redshift gas clouds, the Lyα transition from the first excited energy level to the ground state of the hydrogen atom is usually found to be the only prominent emission lines in the entire spectrum. It is a well-known assumption that high-redshifted hydrogen clouds are the precursors of present-day galaxies. Thus, the investigation of the Lyα line is of paramount importance of the theory of galaxy formation and evolution. The observed Lyα line - or rather, to be precise, its profile - reveals both the complexity of the spatial distribution and of the kinematics of the interstellar gas, and also the nature of the photon source. In this thesis we have developed a code which is capable of solving the three-dimensional frequency-dependent radiative transfer equation for arbitrarily nonrelativistically moving media. The numerical treatment of the associated partial integro-differential equation is an extremely challenging task, since radiation intensity depends on 6 variables, namely 3 space variables, 2 variables describing the direction of photon propagation, and the frequency. With the goal of a quantitative comparison with observational data in mind, the implementation of very efficient methods for a sufficiently accurate solution of the complex radiative transfer problems turned out to be a necessity. The size of the resulting linear system of equations makes the use of parallelization techniques and grid refinement strategies indispensable.

  11. Regeneration of spine disc and joint cartilages under temporal and space modulated laser radiation

    Science.gov (United States)

    Sobol, E.; Shekhter, A.; Baskov, A.; Baskov, V.; Baum, O.; Borchshenko, I.; Golubev, V.; Guller, A.; Kolyshev, I.; Omeltchenko, A.; Sviridov, A.; Zakharkina, O.

    2009-02-01

    The effect of laser radiation on the generation of hyaline cartilage in spine disc and joints has been demonstrated. The paper considers physical processes and mechanisms of laser regeneration, presents results of investigations aimed to optimize laser settings and to develop feedback control system for laser reconstruction of spine discs. Possible mechanisms of laser-induced regeneration include: (1) Space and temporary modulated laser beam induces nonhomogeneous and pulse repetitive thermal expansion and stress in the irradiated zone of cartilage. Mechanical effect due to controllable thermal expansion of the tissue and micro and nano gas bubbles formation in the course of the moderate (up to 45-50 oC) heating of the NP activate biological cells (chondrocytes) and promote cartilage regeneration. (2) Nondestructive laser radiation leads to the formation of nano and micro-pores in cartilage matrix. That promotes water permeability and increases the feeding of biological cells. Results provide the scientific and engineering basis for the novel low-invasive laser procedures to be used in orthopedics for the treatment cartilages of spine and joints. The technology and equipment for laser reconstruction of spine discs have been tested first on animals, and then in a clinical trial. Since 2001 the laser reconstruction of intervertebral discs have been performed for 340 patients with chronic symptoms of low back or neck pain who failed to improve with non-operative care. Substantial relief of back pain was obtained in 90% of patients treated who returned to their daily activities. The experiments on reparation of the defects in articular cartilage of the porcine joints under temporal and spase modulated laser radiation have shown promising results.

  12. Three-dimensional dose-response models of competing risks and natural life span

    International Nuclear Information System (INIS)

    Raabe, O.G.

    1987-01-01

    Three-dimensional dose-rate/time/response surfaces for chronic exposure to carcinogens, toxicants, and ionizing radiation dramatically clarify the separate and interactive roles of competing risks. The three dimensions are average dose rate, exposure time, and risk. An illustration with computer graphics shows the contributions with the passage of time of the competing risks of death from radiation pneumonitis/fibrosis, lung cancer, and natural aging consequent to the inhalation of plutonium-239 dioxide by beagles. These relationships are further evaluated by mathematical stripping with three-dimensional illustrations that graphically show the resultant separate contribution of each fatal effect. Radiation pneumonitis predominates at high dose rates and lung cancer at intermediate dose rates. Low dose rates result in spontaneous deaths from natural aging, yielding a type of practical threshold for lung cancer induction. Risk assessment is benefited by the insights that become apparent with these three-dimensional models. The improved conceptualization afforded by them contributes to the planning and evaluation of epidemiological analyses and experimental studies involving chronic exposure to toxicants

  13. [Application Progress of Three-dimensional Laser Scanning Technology in Medical Surface Mapping].

    Science.gov (United States)

    Zhang, Yonghong; Hou, He; Han, Yuchuan; Wang, Ning; Zhang, Ying; Zhu, Xianfeng; Wang, Mingshi

    2016-04-01

    The booming three-dimensional laser scanning technology can efficiently and effectively get spatial three-dimensional coordinates of the detected object surface and reconstruct the image at high speed,high precision and large capacity of information.Non-radiation,non-contact and the ability of visualization make it increasingly popular in three-dimensional surface medical mapping.This paper reviews the applications and developments of three-dimensional laser scanning technology in medical field,especially in stomatology,plastic surgery and orthopedics.Furthermore,the paper also discusses the application prospects in the future as well as the biomedical engineering problems it would encounter with.

  14. THREE-DIMENSIONAL RADIATIVE TRANSFER MODELING OF THE POLARIZATION OF THE SUN'S CONTINUOUS SPECTRUM

    International Nuclear Information System (INIS)

    Bueno, Javier Trujillo; Shchukina, Nataliya

    2009-01-01

    Polarized light provides the most reliable source of information at our disposal for diagnosing the physical properties of astrophysical plasmas, including the three-dimensional (3D) structure of the solar atmosphere. Here we formulate and solve the 3D radiative transfer problem of the linear polarization of the solar continuous radiation, which is principally produced by Rayleigh and Thomson scattering. Our approach takes into account not only the anisotropy of the solar continuum radiation but also the symmetry-breaking effects caused by the horizontal atmospheric inhomogeneities produced by the solar surface convection. We show that such symmetry-breaking effects do produce observable signatures in Q/I and U/I, even at the very center of the solar disk where we observe the forward scattering case, but their detection would require obtaining very high resolution linear polarization images of the solar surface. Without spatial and/or temporal resolution U/I ∼ 0 and the only observable quantity is Q/I, whose wavelength variation at a solar disk position close to the limb has been recently determined semi-empirically. Interestingly, our 3D radiative transfer modeling of the polarization of the Sun's continuous spectrum in a well-known 3D hydrodynamical model of the solar photosphere shows remarkable agreement with the semi-empirical determination, significantly better than that obtained via the use of one-dimensional (1D) atmospheric models. Although this result confirms that the above-mentioned 3D model was indeed a suitable choice for our Hanle-effect estimation of the substantial amount of 'hidden' magnetic energy that is stored in the quiet solar photosphere, we have found however some small discrepancies whose origin may be due to uncertainties in the semi-empirical data and/or in the thermal and density structure of the 3D model. For this reason, we have paid some attention also to other (more familiar) observables, like the center-limb variation of the

  15. Impact of anisotropic slip on transient three dimensional MHD flow of ferrofluid over an inclined radiate stretching surface

    Directory of Open Access Journals (Sweden)

    A.M. Rashad

    2017-04-01

    Full Text Available The present study explores the impact of anistropic slip on transient three dimensional MHD flow of Cobalt-kerosene ferrofluid over an inclined radiate stretching surface. The governing partial differential equations for this study are solved by the Thomas algorithm with finite-difference type. The impacts of several significant parameters on flow and heat transfer characteristics are exhibited graphically. The conclusion is revealed that the local Nusselt number is significantly promoted due to influence of thermal radiation whereas diminished with elevating the solid volume fraction, magnet parameter and slip factors. Further, the skin friction coefficients visualizes a considerable enhancement with boosting the magnet and radiation parameters, but a prominent reduction is recorded by elevating the solid volume fraction and slip factors.

  16. On the role of radiation and dimensionality in predicting flow opposed flame spread over thin fuels

    Science.gov (United States)

    Kumar, Chenthil; Kumar, Amit

    2012-06-01

    In this work a flame-spread model is formulated in three dimensions to simulate opposed flow flame spread over thin solid fuels. The flame-spread model is coupled to a three-dimensional gas radiation model. The experiments [1] on downward spread and zero gravity quiescent spread over finite width thin fuel are simulated by flame-spread models in both two and three dimensions to assess the role of radiation and effect of dimensionality on the prediction of the flame-spread phenomena. It is observed that while radiation plays only a minor role in normal gravity downward spread, in zero gravity quiescent spread surface radiation loss holds the key to correct prediction of low oxygen flame spread rate and quenching limit. The present three-dimensional simulations show that even in zero gravity gas radiation affects flame spread rate only moderately (as much as 20% at 100% oxygen) as the heat feedback effect exceeds the radiation loss effect only moderately. However, the two-dimensional model with the gas radiation model badly over-predicts the zero gravity flame spread rate due to under estimation of gas radiation loss to the ambient surrounding. The two-dimensional model was also found to be inadequate for predicting the zero gravity flame attributes, like the flame length and the flame width, correctly. The need for a three-dimensional model was found to be indispensable for consistently describing the zero gravity flame-spread experiments [1] (including flame spread rate and flame size) especially at high oxygen levels (>30%). On the other hand it was observed that for the normal gravity downward flame spread for oxygen levels up to 60%, the two-dimensional model was sufficient to predict flame spread rate and flame size reasonably well. Gas radiation is seen to increase the three-dimensional effect especially at elevated oxygen levels (>30% for zero gravity and >60% for normal gravity flames).

  17. Application of a three-dimensional model for assessing effects of small clear-cuttings on radiation and soil temperature

    DEFF Research Database (Denmark)

    Olchev, A.; Radler, K.; Sogachev, Andrey

    2009-01-01

    , solar radiation, wind speed and direction, soil temperatures at 10 and 20 cm depth were measured by five automatic stations within the clear-cut area. One reference station was placed about 100 m from the clear-cut inside the forest stand. Comparisons of modelled and measured solar radiation fluxes...... and soil temperature profiles showed that the model adequately describes the spatial heterogeneity and dynamics of these variables under different weather conditions. The model can be used to explore solar radiation and soil temperature patterns within heterogeneous forest plots, with applications......A three-dimensional model Mixfor-3D of soil–vegetation–atmosphere transfer (SVAT) was developed and applied to estimate possible effects of tree clear-cutting on radiation and soil temperature regimes of a forest ecosystem. The Mixfor-3D model consists of several closely coupled 3D sub...

  18. A practical three-dimensional dosimetry system for radiation therapy

    International Nuclear Information System (INIS)

    Guo Pengyi; Adamovics, John; Oldham, Mark

    2006-01-01

    There is a pressing need for a practical three-dimensional (3D) dosimetry system, convenient for clinical use, and with the accuracy and resolution to enable comprehensive verification of the complex dose distributions typical of modern radiation therapy. Here we introduce a dosimetry system that can achieve this challenge, consisting of a radiochromic dosimeter (PRESAGE trade mark sign ) and a commercial optical computed tomography (CT) scanning system (OCTOPUS trade mark sign ). PRESAGE trade mark sign is a transparent material with compelling properties for dosimetry, including insensitivity of the dose response to atmospheric exposure, a solid texture negating the need for an external container (reducing edge effects), and amenability to accurate optical CT scanning due to radiochromic optical contrast as opposed to light-scattering contrast. An evaluation of the performance and viability of the PRESAGE trade mark sign /OCTOPUS, combination for routine clinical 3D dosimetry is presented. The performance of the two components (scanner and dosimeter) was investigated separately prior to full system test. The optical CT scanner has a spatial resolution of ≤1 mm, geometric accuracy within 1 mm, and high reconstruction linearity (with a R 2 value of 0.9979 and a standard error of estimation of ∼1%) relative to independent measurement. The overall performance of the PRESAGE trade mark sign /OCTOPUS system was evaluated with respect to a simple known 3D dose distribution, by comparison with GAFCHROMIC[reg] EBT film and the calculated dose from a commissioned planning system. The 'measured' dose distribution in a cylindrical PRESAGE trade mark sign dosimeter (16 cm diameter and 11 cm height) was determined by optical-CT, using a filtered backprojection reconstruction algorithm. A three-way Gamma map comparison (4% dose difference and 4 mm distance to agreement), between the PRESAGE trade mark sign , EBT and calculated dose distributions, showed full agreement in

  19. A Three-Dimensional Radiation Transfer Model to Evaluate Performance of Compound Parabolic Concentrator-Based Photovoltaic Systems

    Directory of Open Access Journals (Sweden)

    Jingjing Tang

    2018-04-01

    Full Text Available In the past, two-dimensional radiation transfer models (2-D models were widely used to investigate the optical performance of linear compound parabolic concentrators (CPCs, in which the radiation transfer on the cross-section of CPC troughs is considered. However, the photovoltaic efficiency of solar cells depends on the real incidence angle instead of the projection incidence angle, thus 2-D models can’t reasonably evaluate the photovoltaic performance of CPC-based photovoltaic systems (CPVs. In this work, three-dimensional radiation transfer (3-D model within CPC-θa/θe, the CPC with a maximum exit angle θe for radiation within its acceptance angle (θa, is investigated by means of vector algebra, solar geometry and imaging principle of plane mirror, and effects of geometry of CPV-θa/θe on its annual electricity generation are studied. Analysis shows that, as compared to similar photovoltaic (PV panels, the use of CPCs makes the incident angle of solar rays on solar cells increase thus lowers the photovoltaic conversion efficiency of solar cells. Calculations show that, 2-D models can reasonably predict the optical performance of CPVs, but such models always overestimate the photovoltaic performance of CPVs, and even can’t predict the variation trend of annual power output of CPV-θa/θe with θe. Results show that, for full CPV-θa/θe with a given θa, the annual power output increases with θe first and then comes to a halt as θe > 83°, whereas for truncated CPV-θa/θe with a given geometric concentration (Ct, the annual power output decreases with θe.

  20. Three-dimensional surface scanners compared with standard anthropometric measurements for head shape

    NARCIS (Netherlands)

    Beaumont, C.A.A. (Caroline A.A.); Knoops, P.G.M. (Paul G.M.); Borghi, A. (Alessandro); Jeelani, N.U.O. (N.U. Owase); M.J. Koudstaal (Maarten); S. Schievano (Silvia); D.J. Dunaway (David); Rodriguez-Florez, N. (Naiara)

    2016-01-01

    textabstractThree-dimensional (3D) surface imaging devices designed to capture and quantify craniofacial surface morphology are becoming more common in clinical environments. Such scanners overcome the limitations of two-dimensional photographs while avoiding the ionizing radiation of computed

  1. Three-dimensional surface scanners compared with standard anthropometric measurements for head shape

    NARCIS (Netherlands)

    Beaumont, C.A.A. (Caroline A.A.); Knoops, P.G.M. (Paul G.M.); Borghi, A. (Alessandro); Jeelani, N.U.O. (N.U. Owase); M.J. Koudstaal (Maarten); S. Schievano (Silvia); D.J. Dunaway (David); Rodriguez-Florez, N. (Naiara)

    2017-01-01

    textabstractThree-dimensional (3D) surface imaging devices designed to capture and quantify craniofacial surface morphology are becoming more common in clinical environments. Such scanners overcome the limitations of two-dimensional photographs while avoiding the ionizing radiation of computed

  2. Three-dimensional finite element models of the human pubic symphysis with viscohyperelastic soft tissues.

    Science.gov (United States)

    Li, Zuoping; Alonso, Jorge E; Kim, Jong-Eun; Davidson, James S; Etheridge, Brandon S; Eberhardt, Alan W

    2006-09-01

    Three-dimensional finite element (FE) models of human pubic symphyses were constructed from computed tomography image data of one male and one female cadaver pelvis. The pubic bones, interpubic fibrocartilaginous disc and four pubic ligaments were segmented semi-automatically and meshed with hexahedral elements using automatic mesh generation schemes. A two-term viscoelastic Prony series, determined by curve fitting results of compressive creep experiments, was used to model the rate-dependent effects of the interpubic disc and the pubic ligaments. Three-parameter Mooney-Rivlin material coefficients were calculated for the discs using a heuristic FE approach based on average experimental joint compression data. Similarly, a transversely isotropic hyperelastic material model was applied to the ligaments to capture average tensile responses. Linear elastic isotropic properties were assigned to bone. The applicability of the resulting models was tested in bending simulations in four directions and in tensile tests of varying load rates. The model-predicted results correlated reasonably with the joint bending stiffnesses and rate-dependent tensile responses measured in experiments, supporting the validity of the estimated material coefficients and overall modeling approach. This study represents an important and necessary step in the eventual development of biofidelic pelvis models to investigate symphysis response under high-energy impact conditions, such as motor vehicle collisions.

  3. Crystallization of a self-assembled three-dimensional DNA nanostructure

    International Nuclear Information System (INIS)

    Rendek, Kimberly N.; Fromme, Raimund; Grotjohann, Ingo; Fromme, Petra

    2013-01-01

    In this work, the crystallization of a self-assembling three-dimensional B-DNA nanostructure is described. The powerful and specific molecular-recognition system present in the base-pairing of DNA allows for the design of a plethora of nanostructures. In this work, the crystallization of a self-assembling three-dimensional B-DNA nanostructure is described. The DNA nanostructure consists of six single-stranded oligonucleotides that hybridize to form a three-dimensional tetrahedron of 80 kDa in molecular mass and 20 bp on each edge. Crystals of the tetrahedron have been successfully produced and characterized. These crystals may form the basis for an X-ray structure of the tetrahedron in the future. Nucleotide crystallography poses many challenges, leading to the fact that only 1352 X-ray structures of nucleic acids have been solved compared with more than 80 000 protein structures. In this work, the crystallization optimization for three-dimensional tetrahedra is also described, with the eventual goal of producing nanocrystals to overcome the radiation-damage obstacle by the use of free-electron laser technology in the future

  4. Application of Simulated Three Dimensional CT Image in Orthognathic Surgery

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Hyun Don; Park, Chang Seo [Dept. of Dental Radiology, College of Dentistry, Yensei University, Seoul (Korea, Republic of); Yoo, Sun Kook; Lee, Kyoung Sang [Dept. of Medical Engineering, College of Medicine, Yensei University, Seoul (Korea, Republic of)

    1998-08-15

    In orthodontics and orthognathic surgery, cephalogram has been routine practice in diagnosis and treatment evaluation of craniofacial deformity. But its inherent distortion of actual length and angles during projecting three dimensional object to two dimensional plane might cause errors in quantitative analysis of shape and size. Therefore, it is desirable that three dimensional object is diagnosed and evaluated three dimensionally and three dimensional CT image is best for three dimensional analysis. Development of clinic necessitates evaluation of result of treatment and comparison before and after surgery. It is desirable that patient that was diagnosed and planned by three dimensional computed tomography before surgery is evaluated by three dimensional computed tomography after surgery, too. But Because there is no standardized normal values in three dimension now and three dimensional Computed Tomography needs expensive equipment and because of its expenses and amount of exposure to radiation, limitations still remain to be solved in its application to routine practice. If postoperative three dimensional image is constructed by pre and postoperative lateral and postero-anterior cephalograms and preoperative three dimensional computed tomogram, pre and postoperative image will be compared and evaluated three dimensionally without three dimensional computed tomography after surgery and that will contribute to standardize normal values in three dimension. This study introduced new method that computer-simulated three dimensional image was constructed by preoperative three dimensional computed tomogram and pre and postoperative lateral and postero-anterior cephalograms, and for validation of new method, in four cases of dry skull that position of mandible was displaced and four patients of orthognathic surgery, computer-simulated three dimensional image and actual postoperative three dimensional image were compared. The results were as follows. 1. In four cases of

  5. Application of Simulated Three Dimensional CT Image in Orthognathic Surgery

    International Nuclear Information System (INIS)

    Kim, Hyun Don; Park, Chang Seo; Yoo, Sun Kook; Lee, Kyoung Sang

    1998-01-01

    In orthodontics and orthognathic surgery, cephalogram has been routine practice in diagnosis and treatment evaluation of craniofacial deformity. But its inherent distortion of actual length and angles during projecting three dimensional object to two dimensional plane might cause errors in quantitative analysis of shape and size. Therefore, it is desirable that three dimensional object is diagnosed and evaluated three dimensionally and three dimensional CT image is best for three dimensional analysis. Development of clinic necessitates evaluation of result of treatment and comparison before and after surgery. It is desirable that patient that was diagnosed and planned by three dimensional computed tomography before surgery is evaluated by three dimensional computed tomography after surgery, too. But Because there is no standardized normal values in three dimension now and three dimensional Computed Tomography needs expensive equipment and because of its expenses and amount of exposure to radiation, limitations still remain to be solved in its application to routine practice. If postoperative three dimensional image is constructed by pre and postoperative lateral and postero-anterior cephalograms and preoperative three dimensional computed tomogram, pre and postoperative image will be compared and evaluated three dimensionally without three dimensional computed tomography after surgery and that will contribute to standardize normal values in three dimension. This study introduced new method that computer-simulated three dimensional image was constructed by preoperative three dimensional computed tomogram and pre and postoperative lateral and postero-anterior cephalograms, and for validation of new method, in four cases of dry skull that position of mandible was displaced and four patients of orthognathic surgery, computer-simulated three dimensional image and actual postoperative three dimensional image were compared. The results were as follows. 1. In four cases of

  6. Numerical studies of heat transfer by simultaneous radiative-conduction and radiative-convection in a two dimensional semi-transparent medium

    International Nuclear Information System (INIS)

    Draoui, Abdeslam

    1989-01-01

    The works we present here are on numerical approaches of heat transfer coupling radiation-conduction and radiation-convection within semi-transparent two-dimensional medium. The first part deals with a review of equations of radiative transfer and introduces three numerical methods (Pl, P3, Hottel's zones) which enable one to solve this problem in a two-dimensional environment. After comparing the three methods in the case where radiation is the only mode of transfer, we introduce in the second chapter a study of the coupling of radiation with conduction. So, a fourth method is used to solve this problem. These comparisons lead us to various methods which enable us to show the interest of the spherical harmonics approximations. In the third part, the Pl approximation is kept because it is simple to use, moreover it enables us to introduce both the coupling of radiative transfers with laminar convective equations in a thermally driven two-dimensional cavity. The results show a significant influence of the radiative participation of the fluid on heat and dynamic transfer we met in this type of problem. (author) [fr

  7. Three-dimensional relativistic pair plasma reconnection with radiative feedback in the Crab Nebula

    Energy Technology Data Exchange (ETDEWEB)

    Cerutti, B. [Department of Astrophysical Sciences, Princeton University, Princeton, NJ 08544 (United States); Werner, G. R.; Uzdensky, D. A. [Center for Integrated Plasma Studies, Physics Department, University of Colorado, UCB 390, Boulder, CO 80309-0390 (United States); Begelman, M. C., E-mail: bcerutti@astro.princeton.edu, E-mail: greg.werner@colorado.edu, E-mail: uzdensky@colorado.edu, E-mail: mitch@jila.colorado.edu [JILA, University of Colorado and National Institute of Standards and Technology, UCB 440, Boulder, CO 80309-0440 (United States)

    2014-02-20

    The discovery of rapid synchrotron gamma-ray flares above 100 MeV from the Crab Nebula has attracted new interest in alternative particle acceleration mechanisms in pulsar wind nebulae. Diffuse shock-acceleration fails to explain the flares because particle acceleration and emission occur during a single or even sub-Larmor timescale. In this regime, the synchrotron energy losses induce a drag force on the particle motion that balances the electric acceleration and prevents the emission of synchrotron radiation above 160 MeV. Previous analytical studies and two-dimensional (2D) particle-in-cell (PIC) simulations indicate that relativistic reconnection is a viable mechanism to circumvent the above difficulties. The reconnection electric field localized at X-points linearly accelerates particles with little radiative energy losses. In this paper, we check whether this mechanism survives in three dimension (3D), using a set of large PIC simulations with radiation reaction force and with a guide field. In agreement with earlier works, we find that the relativistic drift kink instability deforms and then disrupts the layer, resulting in significant plasma heating but few non-thermal particles. A moderate guide field stabilizes the layer and enables particle acceleration. We report that 3D magnetic reconnection can accelerate particles above the standard radiation reaction limit, although the effect is less pronounced than in 2D with no guide field. We confirm that the highest-energy particles form compact bunches within magnetic flux ropes, and a beam tightly confined within the reconnection layer, which could result in the observed Crab flares when, by chance, the beam crosses our line of sight.

  8. High-resolution two-dimensional gel analysis of proteins in wing imaginal discs: A data base of Drosophila

    International Nuclear Information System (INIS)

    Santaren, J.F.; Garcia-Bellido, A.

    1990-01-01

    An improved method of high-resolution two-dimensional gel electrophoresis has been used to study the patterns of protein synthesis in wing imaginal discs of late instar larvae of Drosophila melanogaster. A small number of discs were radiolabeled with a mixture of 14 C-labeled amino acids or with [ 35 S]methionine and the pattern of labeled proteins was analyzed. One thousand and twenty-five polypeptides (787 acidic (IEF) and 238 basic (NEPHGE)) from wing discs of several wild-type strains have so far been separated and cataloged. All these polypeptides have been numbered and presented in a reference map for further studies. When comparing patterns of label we have found small quantitative differences in rate of synthesis between individuals of the same strain, not due to sexual differences, and very few quantitative and qualitative differences between groups of individuals of different strains

  9. Three-dimensional ICT reconstruction

    International Nuclear Information System (INIS)

    Zhang Aidong; Li Ju; Chen Fa; Sun Lingxia

    2005-01-01

    The three-dimensional ICT reconstruction method is the hot topic of recent ICT technology research. In the context, qualified visual three-dimensional ICT pictures are achieved through multi-piece two-dimensional images accumulation by, combining with thresholding method and linear interpolation. Different direction and different position images of the reconstructed pictures are got by rotation and interception respectively. The convenient and quick method is significantly instructive to more complicated three-dimensional reconstruction of ICT images. (authors)

  10. Three-dimensional ICT reconstruction

    International Nuclear Information System (INIS)

    Zhang Aidong; Li Ju; Chen Fa; Sun Lingxia

    2004-01-01

    The three-dimensional ICT reconstruction method is the hot topic of recent ICT technology research. In the context qualified visual three-dimensional ICT pictures are achieved through multi-piece two-dimensional images accumulation by order, combining with thresholding method and linear interpolation. Different direction and different position images of the reconstructed pictures are got by rotation and interception respectively. The convenient and quick method is significantly instructive to more complicated three-dimensional reconstruction of ICT images. (authors)

  11. Three-dimensional analysis of craniofacial bones using three-dimensional computer tomography

    Energy Technology Data Exchange (ETDEWEB)

    Ono, Ichiro; Ohura, Takehiko; Kimura, Chu (Hokkaido Univ., Sapporo (Japan). School of Medicine) (and others)

    1989-08-01

    Three-dimensional computer tomography (3DCT) was performed in patients with various diseases to visualize stereoscopically the deformity of the craniofacial bones. The data obtained were analyzed by the 3DCT analyzing system. A new coordinate system was established using the median sagittal plane of the face (a plane passing through sella, nasion and basion) on the three-dimensional image. Three-dimensional profilograms were prepared for detailed analysis of the deformation of craniofacial bones for cleft lip and palate, mandibular prognathia and hemifacial microsomia. For patients, asymmetry in the frontal view and twist-formed complicated deformities were observed, as well as deformity of profiles in the anteroposterior and up-and-down directions. A newly developed technique allows three-dimensional visualization of changes in craniofacial deformity. It would aid in determining surgical strategy, including crani-facial surgery and maxillo-facial surgery, and in evaluating surgical outcome. (N.K.).

  12. Three-dimensional analysis of craniofacial bones using three-dimensional computer tomography

    International Nuclear Information System (INIS)

    Ono, Ichiro; Ohura, Takehiko; Kimura, Chu

    1989-01-01

    Three-dimensional computer tomography (3DCT) was performed in patients with various diseases to visualize stereoscopically the deformity of the craniofacial bones. The data obtained were analyzed by the 3DCT analyzing system. A new coordinate system was established using the median sagittal plane of the face (a plane passing through sella, nasion and basion) on the three-dimensional image. Three-dimensional profilograms were prepared for detailed analysis of the deformation of craniofacial bones for cleft lip and palate, mandibular prognathia and hemifacial microsomia. For patients, asymmetry in the frontal view and twist-formed complicated deformities were observed, as well as deformity of profiles in the anteroposterior and up-and-down directions. A newly developed technique allows three-dimensional visualization of changes in craniofacial deformity. It would aid in determining surgical strategy, including crani-facial surgery and maxillo-facial surgery, and in evaluating surgical outcome. (N.K.)

  13. Trapping of low-mass planets outside the truncated inner edges of protoplanetary discs

    Science.gov (United States)

    Miranda, Ryan; Lai, Dong

    2018-02-01

    We investigate the migration of a low-mass (≲10 M⊕) planet near the inner edge of a protoplanetary disc using two-dimensional viscous hydrodynamics simulations. We employ an inner boundary condition representing the truncation of the disc at the stellar corotation radius. As described by Tsang, wave reflection at the inner disc boundary modifies the Type I migration torque on the planet, allowing migration to be halted before the planet reaches the inner edge of the disc. For low-viscosity discs (α ≲ 10-3), planets may be trapped with semi-major axes as large as three to five times the inner disc radius. In general, planets are trapped closer to the inner edge as either the planet mass or the disc viscosity parameter α increases, and farther from the inner edge as the disc thickness is increased. This planet trapping mechanism may impact the formation and migration history of close-in compact multiplanet systems.

  14. Evolution of viscous discs. 3. Giant discs in symbiotic stars

    Energy Technology Data Exchange (ETDEWEB)

    Bath, G T [Oxford Univ. (UK). Dept. of Astrophysics; Pringle, J E [Cambridge Univ. (UK). Inst. of Astronomy

    1982-10-01

    The structure of time-dependent accretion discs in giant binaries with separation of the order of 10/sup 13/ cm is examined. Radiative ..cap alpha..-viscosity discs with ..cap alpha.. of order unity accreting on to main-sequence stars at accretion rates which generate luminosities greater than a giant companion decay on time-scales of the same order as the binary period, unlike those in dwarf nova binaries which decay on time-scales 100 times longer than the binary period. This results from the lower gravitational potential and consequent larger disc thickness (relative to the radius) of luminous 'giant' discs accreting at high accretion rates. The eruptions of the symbiotic binary C I Cygni are modelled by an ..cap alpha.. = 1 disc with outer radius 8.5 x 10/sup 12/ cm and a sequence of five mass-transfer bursts at rates between 1.5 x 10/sup 21/ and 4 x 10/sup 22/g s/sup -1/.

  15. Design of three-dimensional visualization based on the posterior lumbar pedicle screw fixation

    Directory of Open Access Journals (Sweden)

    Kai XU

    2011-09-01

    Full Text Available Objective To establish a three-dimensional visualization model of posterior lumbar pedicle screw fixation.Methods A patient with lumbar intervertebral disc hernia and another patient with compression fracture of lumbar vertebra were involved in the present study.Both patients underwent multi-slice spiral CT scan before and after lumbar pedicle screw fixation.The degree of preoperative vertebral compression,vertebral morphology before and after surgery,postoperative pedicle screw position,and decompression effects were observed.The original data of the multi-slice spiral CT were inputted into the computer.The three-dimensional reconstructed images of the lumbar and implanted screws were obtained using the software Amira 4.1 to show the three-dimensional shape of the lumbar vertebrae before and after surgery and the location of the implanted screws.Results The morphology and structure of the lumbar vertebrae before and after surgery and of the implanted screws were reconstructed using the digital navigation platform.The reconstructed 3D images could be displayed in multicolor,transparent,or arbitrary combinations.In the 3D surface reconstruction images,the location and structure of the implanted screws could be clearly observed,and the decompression of the spinal cord or nerve roots and the severity of the fracture and the compression of lumbar vertebrae could be fully evaluated.The reconstructed images before operation revealed the position of the vertebral pedicles and provided reference for intraoperative localization.Conclusions The three-dimensional computerized reconstructions of lumbar pedicle screw fixation may be valuable in basic research,clinical experiment,and surgical planning.The software Amira is one of the bases of three-dimensional reconstruction.

  16. Three dimensional strained semiconductors

    Science.gov (United States)

    Voss, Lars; Conway, Adam; Nikolic, Rebecca J.; Leao, Cedric Rocha; Shao, Qinghui

    2016-11-08

    In one embodiment, an apparatus includes a three dimensional structure comprising a semiconductor material, and at least one thin film in contact with at least one exterior surface of the three dimensional structure for inducing a strain in the structure, the thin film being characterized as providing at least one of: an induced strain of at least 0.05%, and an induced strain in at least 5% of a volume of the three dimensional structure. In another embodiment, a method includes forming a three dimensional structure comprising a semiconductor material, and depositing at least one thin film on at least one surface of the three dimensional structure for inducing a strain in the structure, the thin film being characterized as providing at least one of: an induced strain of at least 0.05%, and an induced strain in at least 5% of a volume of the structure.

  17. Three dimensional radiative flow of magnetite-nanofluid with homogeneous-heterogeneous reactions

    Science.gov (United States)

    Hayat, Tasawar; Rashid, Madiha; Alsaedi, Ahmed

    2018-03-01

    Present communication deals with the effects of homogeneous-heterogeneous reactions in flow of nanofluid by non-linear stretching sheet. Water based nanofluid containing magnetite nanoparticles is considered. Non-linear radiation and non-uniform heat sink/source effects are examined. Non-linear differential systems are computed by Optimal homotopy analysis method (OHAM). Convergent solutions of nonlinear systems are established. The optimal data of auxiliary variables is obtained. Impact of several non-dimensional parameters for velocity components, temperature and concentration fields are examined. Graphs are plotted for analysis of surface drag force and heat transfer rate.

  18. Tracing Planets in Circumstellar Discs

    Directory of Open Access Journals (Sweden)

    Uribe Ana L.

    2013-04-01

    Full Text Available Planets are assumed to form in circumstellar discs around young stellar objects. The additional gravitational potential of a planet perturbs the disc and leads to characteristic structures, i.e. spiral waves and gaps, in the disc density profile. We perform a large-scale parameter study on the observability of these planet-induced structures in circumstellar discs in the (submm wavelength range for the Atacama Large (SubMillimeter Array (ALMA. On the basis of hydrodynamical and magneto-hydrodynamical simulations of star-disc-planet models we calculate the disc temperature structure and (submm images of these systems. These are used to derive simulated ALMA maps. Because appropriate objects are frequent in the Taurus-Auriga region, we focus on a distance of 140 pc and a declination of ≈ 20°. The explored range of star-disc-planet configurations consists of six hydrodynamical simulations (including magnetic fields and different planet masses, nine disc sizes with outer radii ranging from 9 AU to 225 AU, 15 total disc masses in the range between 2.67·10-7 M⊙ and 4.10·10-2 M⊙, six different central stars and two different grain size distributions, resulting in 10 000 disc models. At almost all scales and in particular down to a scale of a few AU, ALMA is able to trace disc structures induced by planet-disc interaction or the influence of magnetic fields in the wavelength range between 0.4...2.0 mm. In most cases, the optimum angular resolution is limited by the sensitivity of ALMA. However, within the range of typical masses of protoplane tary discs (0.1 M⊙...0.001 M⊙ the disc mass has a minor impact on the observability. At the distance of 140 pc it is possible to resolve discs down to 2.67·10-6 M⊙ and trace gaps in discs with 2.67·10-4 M⊙ with a signal-to-noise ratio greater than three. In general, it is more likely to trace planet-induced gaps in magneto-hydrodynamical disc models, because gaps are wider in the presence of

  19. Residual stresses in a cast iron automotive brake disc rotor

    International Nuclear Information System (INIS)

    Ripley, Maurice I.; Kirstein, Oliver

    2006-01-01

    Runout, and consequent juddering and pulsation through the brake pedal, is a multi-million dollar per year warranty problem for car manufacturers. There is some suspicion that the runout can be caused by relaxation of residual casting stresses when the disc is overheated during severe-braking episodes. We report here neutron-diffraction measurements of the levels and distribution of residual strains in a used cast iron brake disc rotor. The difficulties of measuring stresses in grey cast iron are outlined and three-dimensional residual-strain distributions are presented and their possible effects discussed

  20. Terahertz computed tomography in three-dimensional using a pyroelectric array detector

    Science.gov (United States)

    Li, Bin; Wang, Dayong; Zhou, Xun; Rong, Lu; Huang, Haochong; Wan, Min; Wang, Yunxin

    2017-05-01

    Terahertz frequency range spans from 0.1 to 10 THz. Terahertz radiation can penetrate nonpolar materials and nonmetallic materials, such as plastics, wood, and clothes. Then the feature makes the terahertz imaging have important research value. Terahertz computed tomography makes use of the penetrability of terahertz radiation and obtains three-dimensional object projection data. In the paper, continuous-wave terahertz computed tomography with a pyroelectric array detectoris presented. Compared with scanning terahertz computed tomography, a pyroelectric array detector can obtain a large number of projection data in a short time, as the acquisition mode of the array pyroelectric detector omit the projection process on the vertical and horizontal direction. With the two-dimensional cross-sectional images of the object are obtained by the filtered back projection algorithm. The two side distance of the straw wall account for 80 pixels, so it multiplied by the pixel size is equal to the diameter of the straw about 6.4 mm. Compared with the actual diameter of the straw, the relative error is 6%. In order to reconstruct the three-dimensional internal structure image of the straw, the y direction range from 70 to 150 are selected on the array pyroelectric detector and are reconstructed by the filtered back projection algorithm. As the pixel size is 80 μm, the height of three-dimensional internal structure image of the straw is 6.48 mm. The presented system can rapidly reconstruct the three-dimensional object by using a pyroelectric array detector and explores the feasibility of on non-destructive evaluation and security testing.

  1. Electromagnetic radiation reaction force and radiation potential in general five-dimensional relativity

    International Nuclear Information System (INIS)

    Lo, C.Y.; Goldstein, G.R.; Napier, A.

    1989-01-01

    A unified theory of electromagnetic and gravitational fields should modify classical electrodynamics to account for the radiation reaction force. A conjecture that the radiation reaction force and the Lorentz force should be distinct, but in unified forms, results in a five-dimensional unified theory of five variables. It is found that a semicylindrical condition can reconcile the apparent differences between a five-dimensional physical space and our four-dimensional perceptions. Analysis of the geodesic equations results in the notion of gauge dynamics which manifests the influence of the unrestricted fifth variable. The element g 55 of the five-dimensional metric is identified as the radiation potential, which can directly determine the radiation reaction force. This gives a distinct physical origin for the radiation process in classical theory. The potential suggests that the electron can have excited states in quantum electrodynamics. This theory is supported with calculations which demonstrate that the motion of the fifth variable directly causes physical changes in the four-dimensional subspace

  2. The three-dimensional microstructure of polycrystalline materials unravelled by synchrotron light

    DEFF Research Database (Denmark)

    Ludwig, W.; King, A.; Herbig, M.

    2011-01-01

    The three-dimensional microstructure of polycrystalline materials unravelled by synchrotron light Synchrotron radiation X-ray imaging and diffraction techniques offer new possibilities for non-destructive bulk characterization of polycrystalline materials. Minute changes in electron density (diff...

  3. Incorporation of Three-dimensional Radiative Transfer into a Very High Resolution Simulation of Horizontally Inhomogeneous Clouds

    Science.gov (United States)

    Ishida, H.; Ota, Y.; Sekiguchi, M.; Sato, Y.

    2016-12-01

    A three-dimensional (3D) radiative transfer calculation scheme is developed to estimate horizontal transport of radiation energy in a very high resolution (with the order of 10 m in spatial grid) simulation of cloud evolution, especially for horizontally inhomogeneous clouds such as shallow cumulus and stratocumulus. Horizontal radiative transfer due to inhomogeneous clouds seems to cause local heating/cooling in an atmosphere with a fine spatial scale. It is, however, usually difficult to estimate the 3D effects, because the 3D radiative transfer often needs a large resource for computation compared to a plane-parallel approximation. This study attempts to incorporate a solution scheme that explicitly solves the 3D radiative transfer equation into a numerical simulation, because this scheme has an advantage in calculation for a sequence of time evolution (i.e., the scene at a time is little different from that at the previous time step). This scheme is also appropriate to calculation of radiation with strong absorption, such as the infrared regions. For efficient computation, this scheme utilizes several techniques, e.g., the multigrid method for iteration solution, and a correlated-k distribution method refined for efficient approximation of the wavelength integration. For a case study, the scheme is applied to an infrared broadband radiation calculation in a broken cloud field generated with a large eddy simulation model. The horizontal transport of infrared radiation, which cannot be estimated by the plane-parallel approximation, and its variation in time can be retrieved. The calculation result elucidates that the horizontal divergences and convergences of infrared radiation flux are not negligible, especially at the boundaries of clouds and within optically thin clouds, and the radiative cooling at lateral boundaries of clouds may reduce infrared radiative heating in clouds. In a future work, the 3D effects on radiative heating/cooling will be able to be

  4. A physical process of the radial acceleration of disc galaxies

    Science.gov (United States)

    Wilhelm, Klaus; Dwivedi, Bhola N.

    2018-03-01

    An impact model of gravity designed to emulate Newton's law of gravitation is applied to the radial acceleration of disc galaxies. Based on this model (Wilhelm et al. 2013), the rotation velocity curves can be understood without the need to postulate any dark matter contribution. The increased acceleration in the plane of the disc is a consequence of multiple interactions of gravitons (called `quadrupoles' in the original paper) and the subsequent propagation in this plane and not in three-dimensional space. The concept provides a physical process that relates the fit parameter of the acceleration scale defined by McGaugh et al. (2016) to the mean free path length of gravitons in the discs of galaxies. It may also explain the gravitational interaction at low acceleration levels in MOdification of the Newtonian Dynamics (MOND, Milgrom 1983, 1994, 2015, 2016). Three examples are discussed in some detail: the spiral galaxies NGC 7814, NGC 6503 and M 33.

  5. Three-dimensional, three-component wall-PIV

    Science.gov (United States)

    Berthe, André; Kondermann, Daniel; Christensen, Carolyn; Goubergrits, Leonid; Garbe, Christoph; Affeld, Klaus; Kertzscher, Ulrich

    2010-06-01

    This paper describes a new time-resolved three-dimensional, three-component (3D-3C) measurement technique called wall-PIV. It was developed to assess near wall flow fields and shear rates near non-planar surfaces. The method is based on light absorption according to Beer-Lambert’s law. The fluid containing a molecular dye and seeded with buoyant particles is illuminated by a monochromatic, diffuse light. Due to the dye, the depth of view is limited to the near wall layer. The three-dimensional particle positions can be reconstructed by the intensities of the particle’s projection on an image sensor. The flow estimation is performed by a new algorithm, based on learned particle trajectories. Possible sources of measurement errors related to the wall-PIV technique are analyzed. The accuracy analysis was based on single particle experiments and a three-dimensional artificial data set simulating a rotating sphere.

  6. Three-dimensional simulations of Nova capsule implosion experiments

    International Nuclear Information System (INIS)

    Marinak, M.M.; Tipton, R.E.; Landen, O.L.

    1995-01-01

    Capsule implosion experiments carried out on the Nova laser are simulated with the three-dimensional HYDRA radiation hydrodynamics code. Simulations of ordered near single mode perturbations indicate that structures which evolve into round spikes can penetrate farthest into the hot spot. Bubble-shaped perturbations can burn through the capsule shell fastest, however, causing even more damage. Simulations of a capsule with multimode perturbations shows spike amplitudes evolving in good agreement with a saturation model during the deceleration phase. The presence of sizable low mode asymmetry, caused either by drive asymmetry or perturbations in the capsule shell, can dramatically affect the manner in which spikes approach the center of the hot spot. Three-dimensional coupling between the low mode shell perturbations intrinsic to Nova capsules and the drive asymmetry brings the simulated yields into closer agreement with the experimental values

  7. Fibrin promotes proliferation and matrix production of intervertebral disc cells cultured in three-dimensional poly(lactic-co-glycolic acid) scaffold.

    Science.gov (United States)

    Sha'ban, Munirah; Yoon, Sun Jung; Ko, Youn Kyung; Ha, Hyun Jung; Kim, Soon Hee; So, Jung Won; Idrus, Ruszymah Bt Hj; Khang, Gilson

    2008-01-01

    Previously, we have proven that fibrin and poly(lactic-co-glycolic acid) (PLGA) scaffolds facilitate cell proliferation, matrix production and early chondrogenesis of rabbit articular chondrocytes in in vitro and in vivo experiments. In this study, we evaluated the potential of fibrin/PLGA scaffold for intervertebral disc (IVD) tissue engineering using annulus fibrosus (AF) and nucleus pulposus (NP) cells in relation to potential clinical application. PLGA scaffolds were soaked in cells-fibrin suspension and polymerized by dropping thrombin-sodium chloride (CaCl(2)) solution. A PLGA-cell complex without fibrin was used as control. Higher cellular proliferation activity was observed in fibrin/PLGA-seeded AF and NP cells at each time point of 3, 7, 14 and 7 days using the MTT assay. After 3 weeks in vitro incubation, fibrin/PLGA exhibited a firmer gross morphology than PLGA groups. A significant cartilaginous tissue formation was observed in fibrin/PLGA, as proven by the development of cells cluster of various sizes and three-dimensional (3D) cartilaginous histoarchitecture and the presence of proteoglycan-rich matrix and glycosaminoglycan (GAG). The sGAG production measured by 1,9-dimethylmethylene blue (DMMB) assay revealed greater sGAG production in fibrin/PLGA than PLGA group. Immunohistochemical analyses showed expressions of collagen type II, aggrecan core protein and collagen type I genes throughout in vitro culture in both fibrin/PLGA and PLGA. In conclusion, fibrin promotes cell proliferation, stable in vitro tissue morphology, superior cartilaginous tissue formation and sGAG production of AF and NP cells cultured in PLGA scaffold. The 3D porous PLGA scaffold-cell complexes using fibrin can provide a vehicle for delivery of cells to regenerate tissue-engineered IVD tissue.

  8. Relationship between spectral reflectance and leaf area index in needleleaf forest: The effect of three-dimensional forest structure and clumping

    International Nuclear Information System (INIS)

    Kobayashi, H.

    2008-01-01

    Toward the reliable estimation of leaf area index (LAI) and fraction of absorbed photosynthetically active radiation (FAPAR), the relationship between LAI/FAPAR and bidirectional reflectance factor (BRF) at the top of canopy should be accurately modeled by the radiation transfer models. These relationships vary with the forest landscape due to its horizontal heterogeneity and needles clumping within shoot. In this study, the effect of the forest heterogeneity on the relationships between BRF and LAI, and NDVI and LAI/FAPAR were examined through the three-dimensional radiative transfer simulation, and were compared with the results from one-dimensional radiative transfer simulation. In addition to the simulation, limitation of one-dimensional radiative transfer simulation was evaluated. The results showed that BRF at red and near infrared, and NDVI had large variations with different forest landscape under the same LAI conditions. However the relationship between NDVI and LAI, and NDVI and FAPAR derived from dense canopy condition were quite similar to the results from one-dimensional model. If we add the shoot clumping effect in one dimensional radiative transfer model as a universal parameter for three-dimensional effect of the forest, one dimensional radiative transfer model can work well for the BRF simulation in spatially heterogeneous landscape except higher LAI conditions

  9. Three-dimensional self-consistent radiation transport model for the fluid simulation of plasma display panel cell

    International Nuclear Information System (INIS)

    Kim, H.C.; Yang, S.S.; Lee, J.K.

    2003-01-01

    In plasma display panels (PDPs), the resonance radiation trapping is one of the important processes. In order to incorporate this effect in a PDP cell, a three-dimensional radiation transport model is self-consistently coupled with a fluid simulation. This model is compared with the conventional trapping factor method in gas mixtures of neon and xenon. It shows the differences in the time evolutions of spatial profile and the total number of resonant excited states, especially in the afterglow. The generation rates of UV light are also compared for the two methods. The visible photon flux reaching the output window from the phosphor layers as well as the total UV photon flux arriving at the phosphor layer from the plasma region are calculated for resonant and nonresonant excited species. From these calculations, the time-averaged spatial profiles of the UV flux on the phosphor layers and the visible photon flux through the output window are obtained. Finally, the diagram of the energy efficiency and the contribution of each UV light are shown

  10. Three-dimensional effects in fracture mechanics

    International Nuclear Information System (INIS)

    Benitez, F.G.

    1991-01-01

    An overall view of the pioneering theories and works, which enlighten the three-dimensional nature of fracture mechanics during the last years is given. the main aim is not an exhaustive reviewing but the displaying of the last developments on this scientific field in a natural way. This work attempts to envisage the limits of disregarding the three-dimensional behaviour in theories, analyses and experiments. Moreover, it tries to draw attention on the scant fervour, although increasing, this three-dimensional nature of fracture has among the scientific community. Finally, a constructive discussion is presented on the use of two-dimensional solutions in the analysis of geometries which bear a three-dimensional configuration. the static two-dimensional solutions and its applications fields are reviewed. also, the static three-dimensional solutions, wherein a comparative analysis with elastoplastic and elastostatic solutions are presented. to end up, the dynamic three-dimensional solutions are compared to the asymptotic two-dimensional ones under the practical applications point of view. (author)

  11. Small angle X-ray scattering experiments with three-dimensional imaging gas detectors

    International Nuclear Information System (INIS)

    La Monaca, A.; Iannuzzi, M.; Messi, R.

    1985-01-01

    Measurements of small angle X-ray scattering of lupolen - R, dry collagen and dry cornea are presented. The experiments have been performed with synchrotron radiation and a new three-dimensional imaging drif-chamber gas detector

  12. Non-axisymmetric line-driven disc winds - I. Disc perturbations

    Science.gov (United States)

    Dyda, Sergei; Proga, Daniel

    2018-04-01

    We study mass outflows driven from accretion discs by radiation pressure due to spectral lines. To investigate non-axisymmetric effects, we use the ATHENA++ code and develop a new module to account for radiation pressure driving. In 2D, our new simulations are consistent with previous 2D axisymmetric solutions by Proga et al., who used the ZEUS 2D code. Specifically, we find that the disc winds are time dependent, characterized by a dense stream confined to ˜45° relative to the disc mid-plane and bounded on the polar side by a less dense, fast stream. In 3D, we introduce a vertical, ϕ-dependent, subsonic velocity perturbation in the disc mid-plane. The perturbation does not change the overall character of the solution but global outflow properties such as the mass, momentum, and kinetic energy fluxes are altered by up to 100 per cent. Non-axisymmetric density structures develop and persist mainly at the base of the wind. They are relatively small, and their densities can be a few times higher than the azimuthal average. The structure of the non-axisymmetric and axisymmetric solutions differ also in other ways. Perhaps most importantly from the observational point of view are the differences in the so-called clumping factors, that serve as a proxy for emissivity due to two body processes. In particular, the spatially averaged clumping factor over the entire fast stream, while it is of a comparable value in both solutions, it varies about 10 times faster in the non-axisymmetric case.

  13. Two-dimensional FSI simulation of closing dynamics of a tilting disc mechanical heart valve.

    Science.gov (United States)

    Govindarajan, V; Udaykumar, H S; Herbertson, L H; Deutsch, S; Manning, K B; Chandran, K B

    2010-03-01

    The fluid dynamics during valve closure resulting in high shear flows and large residence times of particles has been implicated in platelet activation and thrombus formation in mechanical heart valves. Our previous studies with bi-leaflet valves have shown that large shear stresses induced in the gap between the leaflet edge and the valve housing results in relatively high platelet activation levels whereas flow between the leaflets results in shed vortices not conducive to platelet damage. In this study we compare the result of closing dynamics of a tilting disc valve with that of a bi-leaflet valve. The two-dimensional fluid-structure interaction analysis of a tilting disc valve closure mechanics is performed with a fixed grid Cartesian mesh flow solver with local mesh refinement, and a Lagrangian particle dynamic analysis for computation of potential for platelet activation. Throughout the simulation the flow remains in the laminar regime and the flow through the gap width is marked by the development of a shear layer which separates from the leaflet downstream of the valve. Zones of re-circulation are observed in the gap between the leaflet edge and the valve housing on the major orifice region of the tilting disc valve and are seen to be migrating towards the minor orifice region. Jet flow is observed at the minor orifice region and a vortex is formed which sheds in the direction of fluid motion as observed in experiments using PIV measurements. The activation parameter computed for the tilting disc valve, at the time of closure was found to be 2.7 times greater than that of the bi-leaflet mechanical valve and was found to be in the vicinity of the minor orifice region mainly due to the migration of vortical structures from the major to the minor orifice region during the leaflet rebound of the closing phase.

  14. Electron tomography, three-dimensional Fourier analysis and colour prediction of a three-dimensional amorphous biophotonic nanostructure

    Science.gov (United States)

    Shawkey, Matthew D.; Saranathan, Vinodkumar; Pálsdóttir, Hildur; Crum, John; Ellisman, Mark H.; Auer, Manfred; Prum, Richard O.

    2009-01-01

    Organismal colour can be created by selective absorption of light by pigments or light scattering by photonic nanostructures. Photonic nanostructures may vary in refractive index over one, two or three dimensions and may be periodic over large spatial scales or amorphous with short-range order. Theoretical optical analysis of three-dimensional amorphous nanostructures has been challenging because these structures are difficult to describe accurately from conventional two-dimensional electron microscopy alone. Intermediate voltage electron microscopy (IVEM) with tomographic reconstruction adds three-dimensional data by using a high-power electron beam to penetrate and image sections of material sufficiently thick to contain a significant portion of the structure. Here, we use IVEM tomography to characterize a non-iridescent, three-dimensional biophotonic nanostructure: the spongy medullary layer from eastern bluebird Sialia sialis feather barbs. Tomography and three-dimensional Fourier analysis reveal that it is an amorphous, interconnected bicontinuous matrix that is appropriately ordered at local spatial scales in all three dimensions to coherently scatter light. The predicted reflectance spectra from the three-dimensional Fourier analysis are more precise than those predicted by previous two-dimensional Fourier analysis of transmission electron microscopy sections. These results highlight the usefulness, and obstacles, of tomography in the description and analysis of three-dimensional photonic structures. PMID:19158016

  15. Cherenkov radiation-based three-dimensional position-sensitive PET detector: A Monte Carlo study.

    Science.gov (United States)

    Ota, Ryosuke; Yamada, Ryoko; Moriya, Takahiro; Hasegawa, Tomoyuki

    2018-05-01

    Cherenkov radiation has recently received attention due to its prompt emission phenomenon, which has the potential to improve the timing performance of radiation detectors dedicated to positron emission tomography (PET). In this study, a Cherenkov-based three-dimensional (3D) position-sensitive radiation detector was proposed, which is composed of a monolithic lead fluoride (PbF 2 ) crystal and a photodetector array of which the signals can be readout independently. Monte Carlo simulations were performed to estimate the performance of the proposed detector. The position- and time resolution were evaluated under various practical conditions. The radiator size and various properties of the photodetector, e.g., readout pitch and single photon timing resolution (SPTR), were parameterized. The single photon time response of the photodetector was assumed to be a single Gaussian for the simplification. The photo detection efficiency of the photodetector was ideally 100% for all wavelengths. Compton scattering was included in simulations, but partly analyzed. To estimate the position at which a γ-ray interacted in the Cherenkov radiator, the center-of-gravity (COG) method was employed. In addition, to estimate the depth-of-interaction (DOI) principal component analysis (PCA), which is a multivariate analysis method and has been used to identify the patterns in data, was employed. The time-space distribution of Cherenkov photons was quantified to perform PCA. To evaluate coincidence time resolution (CTR), the time difference of two independent γ-ray events was calculated. The detection time was defined as the first photon time after the SPTR of the photodetector was taken into account. The position resolution on the photodetector plane could be estimated with high accuracy, by using a small number of Cherenkov photons. Moreover, PCA showed an ability to estimate the DOI. The position resolution heavily depends on the pitch of the photodetector array and the radiator

  16. Three-dimensional biomedical imaging

    International Nuclear Information System (INIS)

    Robb, R.A.

    1985-01-01

    Scientists in biomedical imaging provide researchers, physicians, and academicians with an understanding of the fundamental theories and practical applications of three-dimensional biomedical imaging methodologies. Succinct descriptions of each imaging modality are supported by numerous diagrams and illustrations which clarify important concepts and demonstrate system performance in a variety of applications. Comparison of the different functional attributes, relative advantages and limitations, complementary capabilities, and future directions of three-dimensional biomedical imaging modalities are given. Volume 1: Introductions to Three-Dimensional Biomedical Imaging Photoelectronic-Digital Imaging for Diagnostic Radiology. X-Ray Computed Tomography - Basic Principles. X-Ray Computed Tomography - Implementation and Applications. X-Ray Computed Tomography: Advanced Systems and Applications in Biomedical Research and Diagnosis. Volume II: Single Photon Emission Computed Tomography. Position Emission Tomography (PET). Computerized Ultrasound Tomography. Fundamentals of NMR Imaging. Display of Multi-Dimensional Biomedical Image Information. Summary and Prognostications

  17. Three-dimensional neuroimaging

    International Nuclear Information System (INIS)

    Toga, A.W.

    1990-01-01

    This book reports on new neuroimaging technologies that are revolutionizing the study of the brain be enabling investigators to visualize its structure and entire pattern of functional activity in three dimensions. The book provides a theoretical and practical explanation of the new science of creating three-dimensional computer images of the brain. The coverage includes a review of the technology and methodology of neuroimaging, the instrumentation and procedures, issues of quantification, analytic protocols, and descriptions of neuroimaging systems. Examples are given to illustrate the use of three-dimensional enuroimaging to quantitate spatial measurements, perform analysis of autoradiographic and histological studies, and study the relationship between brain structure and function

  18. Dosimetric Comparison of Three Dimensional Conformal Radiation Radiotherapy and Helical Tomotherapy Partial Breast Cancer

    International Nuclear Information System (INIS)

    Kim, Dae Woong; Kim, Jong Won; Choi, Yun Kyeong; Kim, Jung Soo; Hwang, Jae Woong; Jeong, Kyeong Sik; Choi, Gye Suk

    2008-01-01

    The goal of radiation treatment is to deliver a prescribed radiation dose to the target volume accurately while minimizing dose to normal tissues. In this paper, we comparing the dose distribution between three dimensional conformal radiation radiotherapy (3D-CRT) and helical tomotherapy (TOMO) plan for partial breast cancer. Twenty patients were included in the study, and plans for two techniques were developed for each patient (left breast:10 patients, right breast:10 patients). For each patient 3D-CRT planning was using pinnacle planning system, inverse plan was made using Tomotherapy Hi-Art system and using the same targets and optimization goals. We comparing the Homogeneity index (HI), Conformity index (CI) and sparing of the organs at risk for dose-volume histogram. Whereas the HI, CI of TOMO was significantly better than the other, 3D-CRT was observed to have significantly poorer HI, CI. The percentage ipsilateral non-PTV breast volume that was delivered 50% of the prescribed dose was 3D-CRT (mean: 40.4%), TOMO (mean: 18.3%). The average ipsilateral lung volume percentage receiving 20% of the PD was 3D-CRT (mean: 4.8%), TOMO (mean: 14.2), concerning the average heart volume receiving 20% and 10% of the PD during treatment of left breast cancer 3D-CRT (mean: 1.6%, 3.0%), TOMO (mean: 9.7%, 26.3%) In summary, 3D-CRT and TOMO techniques were found to have acceptable PTV coverage in our study. However, in TOMO, high conformity to the PTV and effective breast tissue sparing was achieved at the expense of considerable dose exposure to the lung and heart.

  19. Three-dimensional viewing and dosimetric calculations of Au-198 implants of the prostate

    International Nuclear Information System (INIS)

    Avizonis, V.N.; Anderson, K.M.; Jani, S.K.; Hussey, D.H.

    1991-01-01

    Dose gradients for brachytherapy vary considerably in three dimensions, which complicates conventional two-dimensional dosimetry. Recent developments in computer graphics technology have enabled visualization of anatomy and radiation doses in three dimensions. The objective of this paper is to develop a three-dimensional viewing and dosimetry program for brachytherapy and to test this system in phantoms and in patients undergoing Au-198 implants in the prostate. Three-dimensional computer algorithms for the author's Silicon Graphics supercomputing workstation were developed, tested, and modified on the basis of studies in phantoms and patients. Studies were performed on phantoms of known dimensions and gold seeds in known locations to assess the accuracy of volume reconstruction, seed placement, and isodose distribution. Isodose curves generated with the three-dimensional system were compared with those generated by a Theratronics Treatment Planning Computer using conventional methods. Twenty patients with permanent Au-198 interstitial implants in the prostate were similarly studied

  20. Outcome of three-dimensional conformal radiation therapy and intensity-modulated radiation therapy for inoperable locally advanced pancreatic cancer

    International Nuclear Information System (INIS)

    Lu Ningning; Jin Jing; Li Yexiong; Yu Zihao; Liu Xinfan; Wang Weihu; Wang Shulian; Song Yongwen; Liu Yuping

    2009-01-01

    Objective: To evaluate the outcome of radiotherapy for locally advanced pancreatic cancer. Methods: From January 2000 to December 2007, 41 patients with inoperable locally advanced (stage III) pancreatic cancer were treated with three-dimensional conformal radiation therapy(3DCRT) or intensity-modulated radiation therapy (IMRT). Among these patients, 30 received concurrent radio-chemo-therapy. Results: The median survival time(MST) and 1-year overall survival were 9.2 months and 23%. Patients with pretreatment KPS ≥ 80, no regional lymph nodes metastasis, and CR/PR after radiotherapy had better prognosis. The corresponding MSTs were 11.1 months vs 5.8 months (χ 2 =7.50, P=0.006), 10.8 months vs 6.5 months(χ 2 =5.67, P=0.017), and 19.5 months vs 9.1 months (χ 2 =7.28, P=0.007), respectively. Concurrent radio-chemotherapy tended to improve the overall survival(χ 2 =3.25, P=0.072). After radiotherapy, 18 patients had clinical benefit response, mainly being abdominal pain relief. Neither grade 4 hematologic nor grade 3 non-hematologic toxicities were observed. Conclusions: For patients with locally advanced pancreatic cancer, both 3DCRT and IMRT are effective in alleviation of disease-related symptoms. Patients with better performance status before treatment, no regional lymph nodes metastasis, and better response to radiotherapy may have better prognosis. Concurrent radio-chemotherapy trend to improve overall survival when compared with radiotherapy alone. (authors)

  1. Unusual ratio of TL readouts of different discs of personnel monitoring TLD badge based on CaSO4: Dy teflon disc

    International Nuclear Information System (INIS)

    Pradhan, S.M.; Ande, C.D.; Kher, R.K.; Chourasiya, G.; Vashishtha, R.; Gupta, A.K.

    2005-01-01

    In India Personnel Monitoring against external radiation hazard of gamma, beta and X-rays is provided using a TLD badge based on CaSO 4 : Dy Teflon TLD disc. Unusual ratios of TL readouts of different discs of TLD badge (Disc Ratios) observed for service TLD badges of radiation workers were investigated and simulated. Simulations were carried out by exposure of TLD badges by speck type radioactive sources placed in contact of badges, exposure of TLD badges placed on concrete floor to a radiography source. Clues for the simulation were obtained from nature of work, radiological conditions during course of individuals' work whose TLD badges showed the unusual disc ratios and geometrical calculations performed. It is concluded that although the actual exposure condition during use is unknown, the unusual disk ratios observed for the service TLD badges can be simulated and utilized to arrive at probable exposure conditions. The study helped in investigations of the abnormal exposures and assigning doses to the concerned radiation workers. (author)

  2. GLOBAL STRUCTURE OF THREE DISTINCT ACCRETION FLOWS AND OUTFLOWS AROUND BLACK HOLES FROM TWO-DIMENSIONAL RADIATION-MAGNETOHYDRODYNAMIC SIMULATIONS

    International Nuclear Information System (INIS)

    Ohsuga, Ken; Mineshige, Shin

    2011-01-01

    We present the detailed global structure of black hole accretion flows and outflows through newly performed two-dimensional radiation-magnetohydrodynamic simulations. By starting from a torus threaded with weak toroidal magnetic fields and by controlling the central density of the initial torus, ρ 0 , we can reproduce three distinct modes of accretion flow. In model A, which has the highest central density, an optically and geometrically thick supercritical accretion disk is created. The radiation force greatly exceeds the gravity above the disk surface, thereby driving a strong outflow (or jet). Because of mild beaming, the apparent (isotropic) photon luminosity is ∼22L E (where L E is the Eddington luminosity) in the face-on view. Even higher apparent luminosity is feasible if we increase the flow density. In model B, which has moderate density, radiative cooling of the accretion flow is so efficient that a standard-type, cold, and geometrically thin disk is formed at radii greater than ∼7 R S (where R S is the Schwarzschild radius), while the flow is radiatively inefficient otherwise. The magnetic-pressure-driven disk wind appears in this model. In model C, the density is too low for the flow to be radiatively efficient. The flow thus becomes radiatively inefficient accretion flow, which is geometrically thick and optically thin. The magnetic-pressure force, together with the gas-pressure force, drives outflows from the disk surface, and the flow releases its energy via jets rather than via radiation. Observational implications are briefly discussed.

  3. POLDER/Parasol L2 Radiation Budget subset along CloudSat track V001 (PARASOLRB_CPR) at GES DISC

    Data.gov (United States)

    National Aeronautics and Space Administration — This is the POLDER/Parasol Level-2 Radiation Budget Subset, collocated with the CloudSat track. The subset is processed at the A-Train Data Depot of the GES DISC,...

  4. Induction chemotherapy combined with three-dimensional conformal radiation therapy for locally advanced non-small cell lung cancer

    International Nuclear Information System (INIS)

    Zheng Aiqing; Yu Jinming; Zhao Xianguang; Wang Xuetao; Wei Guangsheng

    2005-01-01

    Objective: To evaluate the effect and complication of induction chemotherapy combined with three-dimensional conformal radiation therapy (3DCRT) for locally advanced non small cell lung cancer (NSCLC). Methods: Ninety-two such patients were randomized into radiation therapy alone group(RT-, 50 patients) and induction chemotherapy combined radiotherapy group (CMT-, 42 patients). The induction chemotherapy consisted of 2-4 cycles of platinum-based regimen. Results: The overall median survival time was 15 months with 12 months in the RT group and 18 months in the CMT group (P=0.014) respectively. The 1-year overall survival rates were 48.6% and 71.2% in RT and CMT group, respectively (P=0.004). The 2-year survival rates were 20.8% and 37.6% in RT and CMT group, respectively (P=0.041). Treatment was well tolerated and the toxicities were similar in either group. Conclusion: The addition of induction chemotherapy to 3DCRT takes a survival advantage over 3DCRT alone for Stage III NSCLC without increasing toxicities. (authors)

  5. Magnetic resonance imaging of diseased cervical and lumbar intervertebral discs

    Energy Technology Data Exchange (ETDEWEB)

    Kadoya, Satoru; Nakamura, Tsutomu; Takarada, Akira; Yamamoto, Itaru; Sato, Shuji.

    1989-02-01

    Magnetic resonance images (MRI) of diseased cervical and lumbar intervertebral discs involving both intrinsic and extrinsic cord lesions were examined using either a 0.15 T resistive or a 0.5 T superconductive magnetic imaging system. The vertebrae, intervertebral discs, and spinal cord were delineated on spin-echo (SE) images with a long repetition time (TR) and a short echo time (proton density-weighted image). Protrusion of degenerated intervertebral discs into the spinal canal was clearly demonstrated not only on sagittal but also on parasagittal and transverse views. The location of protruded discs and compression of the spinal cord, caudal sac, and nerve roots were well visualized three-dimensionally. Pathological features of intervertebral discs were well appreciated on T/sub 2/-weighted images with long TR and SE pulse sequences. Degeneration of intervertebral discs resulted in decreased signal intensity in cases of lumbar disc involvement. For suspected myelomalacia, the intrinsic cord lesion resulting from traumatic disc protrusion appeared as focal low signal intensity on T/sub 1/-weithed images and as somewhat high intensity on T/sub 2/ weighted images. The inversion recovery sequence with median inversion time displayed an inferior image of low contrast and was judged uninformative in comparison to SE imags. The findings showed MRI to be an essential diagnostic technique for spinal cord disorders. It clearly pinpoints the anatomic structures of the spine and the features of disc degeneration. Both extrinsic and intrinsic cord abnormalities can be identified with MRI. The selection of proper pulse sequences is required for the differentiation of the object of interest. (Namekawa, K).

  6. Magnetic resonance imaging of diseased cervical and lumbar intervertebral discs

    International Nuclear Information System (INIS)

    Kadoya, Satoru; Nakamura, Tsutomu; Takarada, Akira; Yamamoto, Itaru; Sato, Shuji.

    1989-01-01

    Magnetic resonance images (MRI) of diseased cervical and lumbar intervertebral discs involving both intrinsic and extrinsic cord lesions were examined using either a 0.15 T resistive or a 0.5 T superconductive magnetic imaging system. The vertebrae, intervertebral discs, and spinal cord were delineated on spin-echo (SE) images with a long repetition time (TR) and a short echo time (proton density-weighted image). Protrusion of degenerated intervertebral discs into the spinal canal was clearly demonstrated not only on sagittal but also on parasagittal and transverse views. The location of protruded discs and compression of the spinal cord, caudal sac, and nerve roots were well visualized three-dimensionally. Pathological features of intervertebral discs were well appreciated on T 2 -weighted images with long TR and SE pulse sequences. Degeneration of intervertebral discs resulted in decreased signal intensity in cases of lumbar disc involvement. For suspected myelomalacia, the intrinsic cord lesion resulting from traumatic disc protrusion appeared as focal low signal intensity on T 1 -weithed images and as somewhat high intensity on T 2 weighted images. The inversion recovery sequence with median inversion time displayed an inferior image of low contrast and was judged uninformative in comparison to SE imags. The findings showed MRI to be an essential diagnostic technique for spinal cord disorders. It clearly pinpoints the anatomic structures of the spine and the features of disc degeneration. Both extrinsic and intrinsic cord abnormalities can be identified with MRI. The selection of proper pulse sequences is required for the differentiation of the object of interest. (Namekawa, K)

  7. A three-dimensional X-ray diffraction microscope for deformation studies of polycrystals

    DEFF Research Database (Denmark)

    Fæster Nielsen, Søren; Lauridsen, E.M.; Juul Jensen, D.

    2001-01-01

    -dimensional X-ray diffraction (3DXRD) microscope installed at the European Synchrotron Radiation Facility in Grenoble provides a fast and non-destructive technique for mapping the embedded grains within thick samples in three dimensions. All essential features like the position, volume, orientation, stress...

  8. Pattern check of TLD disc readings - an important tool to identify abnormal conditions in workplace

    International Nuclear Information System (INIS)

    Pradhan, S.M.; Sneha, C.; Bhattacharya, M.; Sahai, M.K.; Pradeep, Ratna; Datta, D.; Bhatnagar, Amit

    2016-01-01

    Personnel monitoring for external radiation using CaSO 4 :Dy based TLD badge is well established in Indian radiation protection program. TLD badge enables evaluation of occupational dose based on the pattern and values of the three disc readings. Different patterns of disc readings are obtained depending on the type and energy of radiation in the workplace. Pattern not conforming to the radiation in the workplace also called as improper pattern can be a useful tool for investigation of any deviation / abnormality in workplace or monitoring practices. The paper presents different examples of improper pattern observed in monitoring that has helped to find out the deviations in the workplace or monitoring practices. Results of the experiments conducted to simulate some of the observed pattern are also presented in the paper

  9. Dynamic analysis of three autoventilated disc brakes

    Directory of Open Access Journals (Sweden)

    Ricardo A. García-León

    2017-09-01

    Full Text Available The braking system of a car must meet several requirements, among which safety is the most important. It is also composed of a set of mechanical parts such as springs, different types of materials (Metallic and Non Metallic, gases and liquids. The brakes must work safely and predictably in all circumstances, which means having a stable level of friction, in any condition of temperature, humidity and salinity of the environment. For a correct design and operation of brake discs, it is necessary to consider different aspects, such as geometry, type of material, mechanical strength, maximum temperature, thermal deformation, cracking resistance, among others. Therefore, the main objective of this work is to analyze the dynamics and kinetics of the brake system from the pedal as the beginning of mathematical calculations to simulate the behavior and Analysis of Finite Elements (FEA, with the help of SolidWorks Simulation Software. The results show that the third brake disc works best in relation to the other two discs in their different working conditions such as speed and displacement in braking, concluding that depending on the geometry of the brake and the cooling channels these systems can be optimized that are of great importance for the automotive industry.

  10. Three dimensional canonical transformations

    International Nuclear Information System (INIS)

    Tegmen, A.

    2010-01-01

    A generic construction of canonical transformations is given in three-dimensional phase spaces on which Nambu bracket is imposed. First, the canonical transformations are defined as based on cannonade transformations. Second, it is shown that determination of the generating functions and the transformation itself for given generating function is possible by solving correspondent Pfaffian differential equations. Generating functions of type are introduced and all of them are listed. Infinitesimal canonical transformations are also discussed as the complementary subject. Finally, it is shown that decomposition of canonical transformations is also possible in three-dimensional phase spaces as in the usual two-dimensional ones.

  11. Grain size segregation in debris discs

    Science.gov (United States)

    Thebault, P.; Kral, Q.; Augereau, J.-C.

    2014-01-01

    Context. In most debris discs, dust grain dynamics is strongly affected by stellar radiation pressure. Because this mechanism is size-dependent, we expect dust grains to be spatially segregated according to their sizes. However, because of the complex interplay between radiation pressure, grain processing by collisions, and dynamical perturbations, this spatial segregation of the particle size distribution (PSD) has proven difficult to investigate and quantify with numerical models. Aims: We propose to thoroughly investigate this problem by using a new-generation code that can handle some of the complex coupling between dynamical and collisional effects. We intend to explore how PSDs behave in both unperturbed discs at rest and in discs pertubed by planetary objects. Methods: We used the DyCoSS code to investigate the coupled effect of collisions, radiation pressure, and dynamical perturbations in systems that have reached a steady-state. We considered two setups: a narrow ring perturbed by an exterior planet, and an extended disc into which a planet is embedded. For both setups we considered an additional unperturbed case without a planet. We also investigated the effect of possible spatial size segregation on disc images at different wavelengths. Results: We find that PSDs are always spatially segregated. The only case for which the PSD follows a standard dn ∝ s-3.5ds law is for an unperturbed narrow ring, but only within the parent-body ring itself. For all other configurations, the size distributions can strongly depart from such power laws and have steep spatial gradients. As an example, the geometrical cross-section of the disc is very rarely dominated by the smallest grains on bound orbits, as it is expected to be in standard PSDs in sq with q ≤ -3. Although the exact profiles and spatial variations of PSDs are a complex function of the set-up that is considered, we are still able to derive some reliable results that will be useful for image or SED

  12. Three-dimensional microbubble streaming flows

    Science.gov (United States)

    Rallabandi, Bhargav; Marin, Alvaro; Rossi, Massimiliano; Kaehler, Christian; Hilgenfeldt, Sascha

    2014-11-01

    Streaming due to acoustically excited bubbles has been used successfully for applications such as size-sorting, trapping and focusing of particles, as well as fluid mixing. Many of these applications involve the precise control of particle trajectories, typically achieved using cylindrical bubbles, which establish planar flows. Using astigmatic particle tracking velocimetry (APTV), we show that, while this two-dimensional picture is a useful description of the flow over short times, a systematic three-dimensional flow structure is evident over long time scales. We demonstrate that this long-time three-dimensional fluid motion can be understood through asymptotic theory, superimposing secondary axial flows (induced by boundary conditions at the device walls) onto the two-dimensional description. This leads to a general framework that describes three-dimensional flows in confined microstreaming systems, guiding the design of applications that profit from minimizing or maximizing these effects.

  13. Cancer Trials Ireland (ICORG) 06-34: A multi-centre clinical trial using three-dimensional conformal radiation therapy to reduce the toxicity of palliative radiation for lung cancer.

    Science.gov (United States)

    McDermott, Ronan L; Armstrong, John G; Thirion, Pierre; Dunne, Mary; Finn, Marie; Small, Cormac; Byrne, Mary; O'Shea, Carmel; O'Sullivan, Lydia; Shannon, Aoife; Kelly, Emma; Hacking, Dayle J

    2018-05-01

    Cancer Trials Ireland (ICORG) 06-34: A multi-centre clinical trial using three-dimensional conformal radiation therapy to reduce the toxicity of palliative radiation for lung cancer. NCT01176487. Trials of radiation therapy for the palliation of intra-thoracic symptoms from locally advanced non-small cell lung cancer (NSCLC) have concentrated on optimising fractionation and dose schedules. In these trials, the rates of oesophagitis induced by this "palliative" therapy have been unacceptably high. In contrast, this non-randomised, single-arm trial was designed to assess if more technically advanced treatment techniques would result in equivalent symptom relief and reduce the side-effect of symptomatic oesophagitis. Thirty-five evaluable patients with symptomatic locally advanced or metastatic NSCLC were treated using a three-dimensional conformal technique (3-DCRT) and standardised dose regimens of 39 Gy in 13 fractions, 20 Gy in 5 fractions or 17 Gy in 2 fractions. Treatment plans sought to minimise oesophageal dose. Oesophagitis was recorded during treatment, at two weeks, one month and three months following radiation therapy and 3-6 monthly thereafter. Mean dose to the irradiated oesophagus was calculated for all treatment plans. Five patients (14%) had experienced grade 2 oesophagitis or dysphagia or both during treatment and 2 other patients had these side effects at the 2-week follow-up. At follow-up of one month after therapy, there was no grade two or higher oesophagitis or dysphagia reported. 22 patients were eligible for assessment of late toxicity. Five of these patients reported oesophagitis or dysphagia (one had grade 3 dysphagia, two had grade 2 oesophagitis, one of whom also had grade 2 dysphagia). Quality of Life (QoL) data at baseline and at 1-month follow up were available for 20 patients. At 1-month post radiation therapy, these patients had slightly less trouble taking a short walk, less shortness of breath, did not feel as weak, had

  14. Flattening and truncation of stellar discs in edge-on spiral galaxies

    NARCIS (Netherlands)

    Kregel, M; van der Kruit, PC; de Grijs, R

    We analyse the global structure of the old stellar discs in 34 edge-on spiral galaxies. The radial and vertical exponential scale parameters of the discs are obtained by applying an improved two-dimensional decomposition technique to our I -band photometry. We find a clear increase in the disc

  15. Characterization of fabricated three dimensional scaffolds of bio ceramic-polymer composite via microstereolithography technique

    International Nuclear Information System (INIS)

    Marina Talib; Covington, J.A.; Bolarinwa, A.

    2013-01-01

    Full-text: Microstereolithography is a method used for rapid proto typing of polymeric and ceramic components. This technique converts a computer-aided design (CAD) to a three dimensional (3D) model, and enables layer per layer fabrication curing a liquid resin with UV-light or laser source. The aim of this project was to formulate photo curable polymer reinforced with synthesized calcium pyrophosphate (CPP), and to fabricate a 3D scaffolds with optimum mechanical properties for specific tissue engineering applications. The photo curable ceramic suspension was prepared with acrylate polyester, multifunctional acrylate monomer with the addition of 50-70 wt % of CPP, photo initiators and photo inhibitors. The 3D structure of disc (5 mm height x 4 mm diameter) was successfully fabricated using Envisiontec Perfactory3. They were then sintered at high temperature for polymer removal, to obtain a ceramic of the desired porosity. The density increased to more than 35 % and the dimensional shrinkage after sintering were 33 %. The discs were then subjected compressive measurement, biodegradation and bioactivity test. Morphology and CPP content of the sintered polymer was investigated with SEM and XRD, respectively. The addition of CPP coupled with high temperature sintering, had a significant effect on the compressive strength exhibited by the bio ceramic. The values are in the range of cancellous bone (2-4 MPa). In biodegradation and bioactivity test, the synthesized CPP induced the formation of apatite layer and its nucleation onto the composite surface. (author)

  16. FACET, Radiation View Factor with Shadowing

    International Nuclear Information System (INIS)

    Shapiro, A.B.

    1988-01-01

    1 - Description of program or function: FACET calculates the radiation geometric view factor (alternatively called shape factor, angle factor, or configuration factor) between surfaces for axisymmetric, two-dimensional planar and three-dimensional geometries with interposed third surface obstructions. FACET was developed to calculate view factors as input data to finite element heat transfer analysis codes. 2 - Method of solution: Three algorithms are incorporated to integrate the view factor equation for three dimensional geometries. The algorithm used for any two surfaces depends on their geometric relationship and whether third surface obstructions exist. The three algorithms are the area integration (AI) method, the line integration method (LI), and the Mitalas and Stephenson (MS) method. The LI method is used to calculate the view factor between two disjoint surfaces. If the two surfaces have an adjoint edge, the MS method is used. The AI method is used if there is self or third surface shadowing. In two-dimensional planar geometries, the view factor between two surfaces is calculated using Hottel's cross string method. For axisymmetric geometries in the absence of shadowing, the view factor between two surfaces is calculated by view factor algebra using the view factors between parallel coaxial discs. In the presence of self or third surface shadowing, the geometry is represented in three dimensions before calculating the view factors

  17. Difficulty in estimation of dose for the abnormal patterns of the TLD disc readings - need investigation and improvement in work practices

    International Nuclear Information System (INIS)

    Madhumita, B.; Ande, C.D.; Sneha, C.; Bakshi, A.K.; Datta, D.

    2018-01-01

    TLD badge based on CaSO 4 :Dy detector used for external radiation monitoring of occupational workers of radiation facilities in India plays a vital role in radiation protection program. Energy and type of radiation in the work-field can be well identified from the dose evaluation algorithm. Algorithm developed earlier use the set of disc ratio from the three disc readings of the TLD badge to arrive at the dose and the type of radiation. Algorithm fails to estimate the dose for the abnormal patterns. The paper discusses the root cause of the abnormal patterns and investigation followed to arrive the estimation of dose

  18. Dosimetry analysis on radiation-induced acute esophagitis after three-dimensional conformal radiotherapy for non-small cell lung cancer

    International Nuclear Information System (INIS)

    ZZhu Shuchai; Cui Yanli; Li Juan; Liu Zhikun; Shen Wenbin; Su Jingwei; Wang Yuxiang

    2010-01-01

    Objective: To analyze the related factors with radiation-induced esophagitis after threedimensional conformal radiotherapy for non-small cell lung cancer (NSCLC), in order to explore the predictors for optimizing the treatment planning of NSCLC. Methods: From Aug 2000 to Dec 2004, 104 NSCLC patients received radiotherapy and were eligible for this study, 45 cases squamous cell carcinoma, 20 cases adenocarcinoma, 33 cases carrying with cancer cells by test and 6 case with no definitive pathologic feature.46 patients were treated with three dimensional conformal radiotherapy (3DCRT), the other 58 patients conventional radiotherapy (CRT) before later-course 3DCRT. All the patients received the prescribed dose between 60-78 Gy and the median dose 66 Gy. The correlation of the variables were evaluated by Spearman relationship analysis. The morbidity of radiation-induced esophagitis was analyzed by X 2 test. The multivariate effect on radiation-induced esophagitis was statistically processed by Logistic regression model. Results: In 104 patients, the morbidity of radiation- induced esophagitis was 46.2%, including 32 cases at grade 1, 15 cases at grade 2, 1 case at grade 3. Univariate analysis showed the maximal and mean dose of esophagus, the volume of esophagus irradiated, the values of V 40 , V 45 , V 50 , V 55 , V 60 , LETT 45 , LETT 50 , LETT 55 , LETT 60 for the esophagus were correlated with radiation-induced esophagitis. Logistic regression model showed that the maximum dose received by the esophagus was the independent factor of ≥ 2 grade radiation-induced esophagitis. Conclusions: The maxmal dose of esophagus received might be the important factor of radiation-induced esophagitis. (authors)

  19. Gravitating discs around black holes

    International Nuclear Information System (INIS)

    Karas, V; Hure, J-M; Semerak, O

    2004-01-01

    Fluid discs and tori around black holes are discussed within different approaches and with the emphasis on the role of disc gravity. First reviewed are the prospects of investigating the gravitational field of a black hole-disc system using analytical solutions of stationary, axially symmetric Einstein equations. Then, more detailed considerations are focused to the middle and outer parts of extended disc-like configurations where relativistic effects are small and the Newtonian description is adequate. Within general relativity, only a static case has been analysed in detail. Results are often very inspiring. However, simplifying assumptions must be imposed: ad hoc profiles of the disc density are commonly assumed and the effects of frame-dragging are completely lacking. Astrophysical discs (e.g. accretion discs in active galactic nuclei) typically extend far beyond the relativistic domain and are fairly diluted. However, self-gravity is still essential for their structure and evolution, as well as for their radiation emission and the impact on the surrounding environment. For example, a nuclear star cluster in a galactic centre may bear various imprints of mutual star-disc interactions, which can be recognized in observational properties, such as the relation between the central mass and stellar velocity dispersion. (topical review)

  20. Therapeutic effect analysis of three dimensional conformal radiotherapy non-small cell lung cancer

    International Nuclear Information System (INIS)

    Yao Zhijun; Cao Yongzhen; Zhang Wenxue; Liang Feng

    2012-01-01

    Objective: To analyse the treatment effect of non-small cell lung cancer of three dimensional conformal radiotherapy (3D-CRT) and to study the effect of patient survival related factors. Methods: Retrospective analysis was mack for 136 cases of non-small cell lung cancer, all accept 3D-CRT, through the case data collection and long-term follow-up, using the single factor and multiple factor analysis survival time and its influencing factors. Results: The recent curative effects of 136 cases of patients with three dimensional conformal radiotherapy: Complete response (CR) 14.7% (20/136), partial response (PR) 60.3 (82/136), stable disease(SD) 19.9% (27/136), progression disease (PD) 5.1% (7/136), total effective rate is 75% (102/136). One, two, three, five year survival rate is 79.4%, 45.4%, 22.1%, 12.5%. Side effects: Class 1 radiated esophagitis 35 cases, Class 2 radiated esophagitis 16 cases, Class 3 and above radiated esophagitis 0 case. Class I radiated pneumonia 20 cases, Class 2 radiated pneumonia 9 cases, Class 3 radiated pneumonia 0 case. Single factor analysis shows the influence of gender, age, pathology, phase, dose, and first-phase curative effect to the survival time are of a statistical significance, Multiple factor analysis showed KPS score, phase, dose, first-phase curative effect are the survival time independent factors. Conclusion: 3D-CRT for patients with non-small cell lung carcinoma is a safe, effective treatment method, Side effects are relatively low, and the patients survival time is long after radiotherapy. (authors)

  1. Flux canceling in three-dimensional radiative magnetohydrodynamic simulations

    Science.gov (United States)

    Thaler, Irina; Spruit, H. C.

    2017-05-01

    We aim to study the processes involved in the disappearance of magnetic flux between regions of opposite polarity on the solar surface using realistic three-dimensional (3D) magnetohydrodynamic (MHD) simulations. "Retraction" below the surface driven by magnetic forces is found to be a very effective mechanism of flux canceling of opposite polarities. The speed at which flux disappears increases strongly with initial mean flux density. In agreement with existing inferences from observations we suggest that this is a key process of flux disappearance within active complexes. Intrinsic kG strength concentrations connect the surface to deeper layers by magnetic forces, and therefore the influence of deeper layers on the flux canceling process is studied. We do this by comparing simulations extending to different depths. For average flux densities of 50 G, and on length scales on the order of 3 Mm in the horizontal and 10 Mm in depth, deeper layers appear to have only a mild influence on the effective rate of diffusion.

  2. Three-Dimensional, Transgenic Cell Models to Quantify Space Genotoxic Effects

    Science.gov (United States)

    Gonda, S. R.; Sognier, M. A.; Wu, H.; Pingerelli, P. L.; Glickman, B. W.; Dawson, David L. (Technical Monitor)

    1999-01-01

    The space environment contains radiation and chemical agents known to be mutagenic and carcinogenic to humans. Additionally, microgravity is a complicating factor that may modify or synergize induced genotoxic effects. Most in vitro models fail to use human cells (making risk extrapolation to humans more difficult), overlook the dynamic effect of tissue intercellular interactions on genotoxic damage, and lack the sensitivity required to measure low-dose effects. Currently a need exists for a model test system that simulates cellular interactions present in tissue, and can be used to quantify genotoxic damage induced by low levels of radiation and chemicals, and extrapolate assessed risk to humans. A state-of-the-art, three-dimensional, multicellular tissue equivalent cell culture model will be presented. It consists of mammalian cells genetically engineered to contain multiple copies of defined target genes for genotoxic assessment,. NASA-designed bioreactors were used to coculture mammalian cells into spheroids, The cells used were human mammary epithelial cells (H184135) and Stratagene's (Austin, Texas) Big Blue(TM) Rat 2 lambda fibroblasts. The fibroblasts were genetically engineered to contain -a high-density target gene for mutagenesis (60 copies of lacl/LacZ per cell). Tissue equivalent spheroids were routinely produced by inoculation of 2 to 7 X 10(exp 5) fibroblasts with Cytodex 3 beads (150 micrometers in diameter). at a 20:1 cell:bead ratio, into 50-ml HARV bioreactors (Synthecon, Inc.). Fibroblasts were cultured for 5 days, an equivalent number of epithelial cells added, and the fibroblast/epithelial cell coculture continued for 21 days. Three-dimensional spheroids with diameters ranging from 400 to 600 micrometers were obtained. Histological and immunohistochemical Characterization revealed i) both cell types present in the spheroids, with fibroblasts located primarily in the center, surrounded by epithelial cells; ii) synthesis of extracellular matrix

  3. DZ Chamaeleontis: a bona fide photoevaporating disc

    Science.gov (United States)

    Canovas, H.; Montesinos, B.; Schreiber, M. R.; Cieza, L. A.; Eiroa, C.; Meeus, G.; de Boer, J.; Ménard, F.; Wahhaj, Z.; Riviere-Marichalar, P.; Olofsson, J.; Garufi, A.; Rebollido, I.; van Holstein, R. G.; Caceres, C.; Hardy, A.; Villaver, E.

    2018-02-01

    Context. DZ Cha is a weak-lined T Tauri star (WTTS) surrounded by a bright protoplanetary disc with evidence of inner disc clearing. Its narrow Hα line and infrared spectral energy distribution suggest that DZ Cha may be a photoevaporating disc. Aims: We aim to analyse the DZ Cha star + disc system to identify the mechanism driving the evolution of this object. Methods: We have analysed three epochs of high resolution optical spectroscopy, photometry from the UV up to the sub-mm regime, infrared spectroscopy, and J-band imaging polarimetry observations of DZ Cha. Results: Combining our analysis with previous studies we find no signatures of accretion in the Hα line profile in nine epochs covering a time baseline of 20 yr. The optical spectra are dominated by chromospheric emission lines, but they also show emission from the forbidden lines [SII] 4068 and [OI] 6300Å that indicate a disc outflow. The polarized images reveal a dust depleted cavity of 7 au in radius and two spiral-like features, and we derive a disc dust mass limit of Mdust 80 MJup) companions are detected down to 0.̋07 ( 8 au, projected). Conclusions: The negligible accretion rate, small cavity, and forbidden line emission strongly suggests that DZ Cha is currently at the initial stages of disc clearing by photoevaporation. At this point the inner disc has drained and the inner wall of the truncated outer disc is directly exposed to the stellar radiation. We argue that other mechanisms like planet formation or binarity cannot explain the observed properties of DZ Cha. The scarcity of objects like this one is in line with the dispersal timescale (≲105 yr) predicted by this theory. DZ Cha is therefore an ideal target to study the initial stages of photoevaporation. Based on observations collected at the European Organisation for Astronomical Research in the Southern Hemisphere under ESO programme 097.C-0536. Based on data obtained from the ESO Science Archive Facility under request number 250112.

  4. Image-guided stereotactic surgery using ultrasonography and reconstructive three-dimensional CT-imaging system

    International Nuclear Information System (INIS)

    Kawamura, Hirotsune; Iseki, Hiroshi; Umezawa, Yoshihiro

    1991-01-01

    A new simulation and navigation system utilizing three-dimensional CT images has been developed for image-guided stereotactic surgery. Preoperative CT images are not always useful in predicting the intraoperative location of lesions, for cerebral lesions are easily displaced or distorted by gravity, brain retraction, and/or CSF aspiration during operative procedure. This new system, however, has the advantage that the intraoperative locations of intracranial lesions or the anatomical structures of the brain can be precisely confirmed during stereotactic surgery. Serial CT images were obtained from a patient whose head had been fixed to the ISEKI CT-guided stereotactic frame. The data of serial CT images were saved on a floppy disc and then transferred to the work station (IRIS) using the off line. In order to find the best approach angle for ultrasound-guided stereotactic surgery, three-dimenstional CT images were reconstructed using the work station. The site of the craniotomy or the angle of the trajectory of the ultrasound probe was measured preoperatively based on the three-dimensional CT images. Then, in the operating room, the patient's head was fixed to the ISEKI frame with the subframe at the same position as before according to the measurement of the CT images. In a case of cystic glioma, the predicable ultrasonograms from three-dimensional reconstructive CT images were ascertained to correspond well to the actual ultrasound images during ultrasound-guided stereotactic surgery. Therefore, the new simulation and navigation system can be judged to be a powerful operative supporting modality for correcting the locations of cerebral lesions; it allows one to perform stereotactic surgery more accurately and less invasively. (author)

  5. Three-dimensional cloud characterization from paired whole-sky imaging cameras

    International Nuclear Information System (INIS)

    Allmen, M.; Kegelmeyer, W.P. Jr.

    1994-01-01

    Three-dimensional (3-D) cloud characterization permits the derivation of important cloud geometry properties such as fractional cloudiness, mean cloud and clear length, aspect ratio, and the morphology of cloud cover. These properties are needed as input to the hierarchical diagnosis (HD) and instantaneous radiative transfer (IRF) models, to validate sub-models for cloud occurrence and formation, and to Central Site radiative flux calculations. A full 3-D characterization will eventually require the integration of disparate Cloud and Radiation Testbed (CART) data sources: whole-sky imagers (WSIs), radar, satellites, ceilometers, volume-imaging lidar, and other sensors. In this paper, we demonstrate how an initial 3-D cloud property, cloud base height, can be determined from fusing paired times series of images from two whole-sky imagers

  6. Deep-down ionization of protoplanetary discs

    Science.gov (United States)

    Glassgold, A. E.; Lizano, S.; Galli, D.

    2017-12-01

    The possible occurrence of dead zones in protoplanetary discs subject to the magneto-rotational instability highlights the importance of disc ionization. We present a closed-form theory for the deep-down ionization by X-rays at depths below the disc surface dominated by far-ultraviolet radiation. Simple analytic solutions are given for the major ion classes, electrons, atomic ions, molecular ions and negatively charged grains. In addition to the formation of molecular ions by X-ray ionization of H2 and their destruction by dissociative recombination, several key processes that operate in this region are included, e.g. charge exchange of molecular ions and neutral atoms and destruction of ions by grains. Over much of the inner disc, the vertical decrease in ionization with depth into the disc is described by simple power laws, which can easily be included in more detailed modelling of magnetized discs. The new ionization theory is used to illustrate the non-ideal magnetohydrodynamic effects of Ohmic, Hall and Ambipolar diffusion for a magnetic model of a T Tauri star disc using the appropriate Elsasser numbers.

  7. Dust discs around low-mass main-sequence stars

    International Nuclear Information System (INIS)

    Wolstencroft, R.D.; Walker, H.J.

    1988-01-01

    Current understanding of the formation of circumstellar discs as a natural accompaniment to the process of low-mass star formation is briefly reviewed. Models of the thermal emission from the dust discs around the prototype stars α Lyr, α PsA, β Pic and ε Eri are discussed, which indicate that the central regions of three of these discs are almost devoid of dust within radii ranging between 17 and 26 AU, with the temperature of the hottest dust lying between about 115 and 210 K. One possible explanation of the dust-free zones is the presence of a planet at the inner boundary of each cloud that sweeps up grains crossing its orbit. The colour, diameter and thickness of the optical image of β Pic, obtained by coronagraphic techniques, have provided further information on the size, radial distribution of number density and orbital inclination of the grains. The difference in surface brightness on the two sides of the disc is puzzling, but might be explained if the grains are elongated and aligned by the combined effects of a stellar wind and a magnetic field of spiral configuration. Finally, we discuss the orbital evolution and lifetimes of particles in these discs, which are governed primarily by radiation pressure, Poynting-Robertson drag and grain-grain collisions. (author)

  8. Fragmentation Energy-Saving Theory of Full Face Rock Tunnel Boring Machine Disc Cutters

    Science.gov (United States)

    Zhang, Zhao-Huang; Gong, Guo-Fang; Gao, Qing-Feng; Sun, Fei

    2017-07-01

    Attempts to minimize energy consumption of a tunnel boring machine disc cutter during the process of fragmentation have largely focused on optimizing disc-cutter spacing, as determined by the minimum specific energy required for fragmentation; however, indentation tests showed that rock deforms plastically beneath the cutters. Equations for thrust were developed for both the traditional, popularly employed disc cutter and anew design based on three-dimensional theory. The respective energy consumption for penetration, rolling, and side-slip fragmentations were obtained. A change in disc-cutter fragmentation angles resulted in a change in the nature of the interaction between the cutter and rock, which lowered the specific energy of fragmentation. During actual field excavations to the same penetration length, the combined energy consumption for fragmentation using the newly designed cutters was 15% lower than that when using the traditional design. This paper presents a theory for energy saving in tunnel boring machines. Investigation results showed that the disc cutters designed using this theory were more durable than traditional designs, and effectively lowered the energy consumption.

  9. Finite element study of three dimensional radiative nano-plasma flow subject to Hall and ion slip currents

    Directory of Open Access Journals (Sweden)

    M. Nawaz

    Full Text Available In this article, we developed a computer code of Galerikan Finite Element method (GFEM for three dimensional flow equations of nano-plasma fluid (blood in the presence of uniform applied magnetic field when Hall and ion slip current are significant. Lorentz force is calculated through generalized Ohm’s law with Maxwell equations. A series of numerical simulations are carried out to search ηmax and algebraic equations are solved by Gauss-Seidel method with simulation tolerance 10-8. Simulated results for special case have an excellent agreement with the already published results. Velocity components and temperature of the nano-plasma (blood are influenced significantly by the inclusion of nano-particles of Copper (Cu and Silver (Ag. Heat enhancement is observed when copper and silver nonmagnetic nanoparticles are used instead of simple base fluid (conventional fluid. Radiative nature of nano-plasma in the presence of magnetic field causes a decrease in the temperature due to the transfer of heat by the electromagnetic waves. In contrast to this, due to heat dissipated by Joule heating and viscous dissipation phenomena, temperature of nano-plasmaincreases as thermal radiation parameter is increased. Thermal boundary layer thickness can be controlled by using radiative fluid instead of non-radiative fluid. Momentum boundary layer thickness can be reduced by increasing the intensity of the applied magnetic field. Temperature of plasma in the presence magnetic field is higher than the plasma in the absence of magnetic field. Keywords: Nanofluid, Grid independent study, Convergence, Error analysis, Skin friction, Joule heating, Viscous dissipation, Hall and ion currents

  10. Actuator disc edge singularity. The key to a revised actuator disc concept and momentum theory

    Energy Technology Data Exchange (ETDEWEB)

    Kuik, G.A.M. van (The Wind Energy Group of the Technical University Eindhoven (NL))

    1989-01-01

    Since the beginning of rotor aerodynamics the actuator disc momentum theory occupies a prominant place in almost any textbook on this subject. Specially in axial flow the theory provides an easy and rather accurate performance prediction. The results first obtained by Lanchester for the induced power of a hovering rotor and the maximum power of a wind turbine are still used as guidelines for complicated calculations. On the other hand, experimental results for propellers are known to deviate systematically (some 10%) from the momentum theory results. This is commonly attributed to the differences between a real rotor and an actuator disc. However, some actuator disc- and actuator strip (the 2-dimensional version) experiments are described in literature, showing the same deviations from momentum theory results. Therefore, apart from the question how representative an actuator disc is for a real rotor, the actuator disc concept itself may be inadequate. This problem is the subject of the work describe here. It will be shown that the classical actuator disc concept ignores discrete forces resulting from a flow singularity at the edge of the disc. The (extended) momentum theory, applied to this actuator strip model, shows a shift of the results towards the experimental data, and for the static case (hover) even a quantitative agreement is obtained. (author) 12 refs.

  11. Hypertext and three-dimensional computer graphics in an all digital PC-based CAI workstation.

    Science.gov (United States)

    Schwarz, D. L.; Wind, G. G.

    1991-01-01

    In the past several years there has been an enormous increase in the number of computer-assisted instructional (CAI) applications. Many medical educators and physicians have recognized the power and utility of hypertext. Some developers have incorporated simple diagrams, scanned monochrome graphics or still frame photographs from a laser disc or CD-ROM into their hypertext applications. These technologies have greatly increased the role of the microcomputer in education and training. There still remain numerous applications for these tools which are yet to be explored. One of these exciting areas involves the use of three-dimensional computer graphics. An all digital platform increases application portability. Images Figure 1 Figure 2 Figure 3 Figure 4 PMID:1807767

  12. Radiation-induced esophagitis in local advanced non-small cell lung cancer after three-dimensional conformal radiotherapy

    International Nuclear Information System (INIS)

    Tian Dandan; Wang Yuxiang; Qiu Rong; Zhu Shuchai; Tian Xiuming; Qiao Xueying

    2014-01-01

    Objective: To explore radiation-induced esophagitis and its related factors in the patients with local advanced non-small cell lung cancer (NSCLC) which were treated with three-dimensional conformal radiation therapy (3D-CRT). Methods: From January 2001 to December 2008, 203 patients who suffered from stage Ⅲ NSCLC were achieved, including 163 males and 40 females, with a median age of 63 years old, while 79 cases were in stage Ⅲ_a and 124 in stage Ⅲ_b. The equivalent median dose of tumor was 62 Gy(range of 50-78 Gy). Among them, 74 cases were administered with radiotherapy alone, 45 with sequential radiotherapy and chemotherapy, 87 cases with concurrent radiochemotherapy. Radiation esophagitis was evaluated with RTOG standard. The dosimetric parameters was estimated from dose volume histogrma (DVH). The clinical and dosimetric parameters of radiation esophagitis were evaluated by spearman correlatived univariate and Logistic multivariable analysis.Results After radiotherapy, out of 203 patients, 87 had acute radiation esophagitis(RE), 47 in grade 1, 37 in grade 2, and 3 in grade 3 RE. According to spearman correlatived analysis, the correlatived factors included ages, chemotherapy, GTV, PTV, the mean doses of PTV and lung, the max and mean dose of esophagus, V_4_0, V_4_5, V_5_0, V_5_5, V_6_0, length of esophagus (total circumference) treated with 45 Gy (LETT_4_5), and LETT_5_0 (r = -0.162-0.235, P 0.05). There were 21 factors, such as gender, age, smoking, clinical stage, site of tumor, chemotherapy, GTV, PTV, mean dose of PTV and lung, max and mean dose of esophagus, V_4_0-V_6_0 of esophagus, LETT_4_5_-_6_0, incorporated into multivariable analysis, only chemotherapy and V_4_5 of esophagus were independent predicted factors(Wald = 4.626, 9.882, P < 0.05). Conclusions: In local advanced NSCLC after 3D-CRT, chemotherapy(especially concurrent radiochemotherapy) could increase radiation-induced esophagitis. The parameter of DVH could also be used to predict

  13. The effect of ultraviolet and visible radiation on the readout obtained from γ-irradiated and unirradiated CaSO4:Dy in teflon discs

    International Nuclear Information System (INIS)

    Bartnik, D.L.; Calvert, R.L.; Young, J.G.

    1982-07-01

    The effect of ultraviolet and visible radiation on the readout obtained from the main dosimetry peak of CaSO 4 :Dy in teflon discs is explained by the net result of three separate factors, namely (i) an inherent response, (ii) a phototransfer and (iii) an optical bleaching. Their dependence on wavelength, irradiance and radiant exposure has been studied using a fluorescent light enclosed in a perspex diffuser and a 200W mercury-xenon lamp in conjunction with narrow bandpass filters to isolate specific wavelengths

  14. Three-dimensional magnetospheric equilibrium with isotropic pressure

    International Nuclear Information System (INIS)

    Cheng, C.Z.

    1995-05-01

    In the absence of the toroidal flux, two coupled quasi two-dimensional elliptic equilibrium equations have been derived to describe self-consistent three-dimensional static magnetospheric equilibria with isotropic pressure in an optimal (Ψ,α,χ) flux coordinate system, where Ψ is the magnetic flux function, χ is a generalized poloidal angle, α is the toroidal angle, α = φ - δ(Ψ,φ,χ) is the toroidal angle, δ(Ψ,φ,χ) is periodic in φ, and the magnetic field is represented as rvec B = ∇Ψ x ∇α. A three-dimensional magnetospheric equilibrium code, the MAG-3D code, has been developed by employing an iterative metric method. The main difference between the three-dimensional and the two-dimensional axisymmetric solutions is that the field-aligned current and the toroidal magnetic field are finite for the three-dimensional case, but vanish for the two-dimensional axisymmetric case. With the same boundary flux surface shape, the two-dimensional axisymmetric results are similar to the three-dimensional magnetosphere at each local time cross section

  15. Three dimensional visualization of medical images

    International Nuclear Information System (INIS)

    Suto, Yasuzo

    1992-01-01

    Three dimensional visualization is a stereoscopic technique that allows the diagnosis and treatment of complicated anatomy site of the bone and organ. In this article, the current status and technical application of three dimensional visualization are introduced with special reference to X-ray CT and MRI. The surface display technique is the most common for three dimensional visualization, consisting of geometric model, voxel element, and stereographic composition techniques. Recent attention has been paid to display method of the content of the subject called as volume rendering, whereby information on the living body is provided accurately. The application of three dimensional visualization is described in terms of diagnostic imaging and surgical simulation. (N.K.)

  16. (Weakly) three-dimensional caseology

    International Nuclear Information System (INIS)

    Pomraning, G.C.

    1996-01-01

    The singular eigenfunction technique of Case for solving one-dimensional planar symmetry linear transport problems is extended to a restricted class of three-dimensional problems. This class involves planar geometry, but with forcing terms (either boundary conditions or internal sources) which are weakly dependent upon the transverse spatial variables. Our analysis involves a singular perturbation about the classic planar analysis, and leads to the usual Case discrete and continuum modes, but modulated by weakly dependent three-dimensional spatial functions. These functions satisfy parabolic differential equations, with a different diffusion coefficient for each mode. Representative one-speed time-independent transport problems are solved in terms of these generalised Case eigenfunctions. Our treatment is very heuristic, but may provide an impetus for more rigorous analysis. (author)

  17. Radiation Damage and Dimensional Changes

    International Nuclear Information System (INIS)

    El-Barbary, A.A.; Lebda, H.I.; Kamel, M.A.

    2009-01-01

    The dimensional changes have been modeled in order to be accommodated in the reactor design. This study has major implications for the interpretation of damage in carbon based nuclear fission and fusion plant materials. Radiation damage of graphite leads to self-interstitials and vacancies defects. The aggregation of these defects causes dimensional changes. Vacancies aggregate into lines and disks which heal and contract the basal planes. Interstitials aggregate into interlayer disks which expand the dimension

  18. Primary observing pulmonary function variety following three-dimensional conformal radiation therapy of III phase non-small cell lung cancer

    International Nuclear Information System (INIS)

    Cai Feng; Li Guang; Zhao Yuxia; Dang Jun; Yao Lei; Wu Chunli

    2006-01-01

    Objective: To explore the pulmonary function, DVH and radiation pneumonitis after three-dimensional conformal radiation treatment of III phase non-small-cell lung cancer. Methods: 71 patients (male 52, female 19, median age 63, KPS≥80) were evaluated by pulmonary function tests before radiotherapy and in M1 and M3 after radiotherapy respectively. After 3 months of follow-up time, it reviewed the appearance and grade of radiation pneumonitis. Then V 20 , V 30 and MLD were worked out from dose volume histogram. Results: All patients completed radiotherapy, and total dose was 66-70 Gy. FVC (L), FEV 1 (L) and C L CO were (2.58±0.65) L, (1.85±0.58) L and (15.15±4.65)ml/(min) before radio- therapy, with(2.96±0.76) L, (2.13±0.65) L and (14.71±3.92) ml/(min) in M1 after radiotherapy, with (2.65±0.61) L, (1.92±0.52) L and (13.15±3.71)ml/(min)in M3 after radiotherapy. The accidence of radiation pneumonitis was 30%, moderate and severe radiation pneumonitis was 7%. With V 20 , V 30 and MLD increasing, the grade of radiation pneumonitis was increasing. V 20 , V 30 and MLD were related to the change in C L CO value among before, M1 and M3 after radiotherapy, and the correlation coefficient was more than 0.2. Conclusions: There is a relationship in the pulmonary fiction, DVH and radiation pneumonitis surely. The change in C L CO value between before radiotherapy and M1 after radiotherapy could predict the radiation pneumonitis. V 20 , V 30 and MLD are not only correlated to radiation pneumonitis evidently but the change in FEV 1 and C L CO after radiotherapy. (authors)

  19. The value of 18F-FDG PET in three-dimensional conformal radiotherapy of cancer

    International Nuclear Information System (INIS)

    Lv Huiqing; Zhang Zhongmin; Lv Zhonghong

    2006-01-01

    Three-dimensional conformal radiotherapy (3D-CRT) is based on an extensive use of modern medical imaging techniques. Delineation of the gross tumor volume and organs at risk constitutes one of the most important phases of conformal radiotherapy procedures. 18 F-fluorodeoxyglucose ( 18 F-FDG) PET possesses greater sensitivity and accuracy in detecting diseased lymph nodes, is an important staging examination for patients considered for radiation treatment with curative intent. 18 F-FDG PET has an important role in delineation of gross tumor volume for patients treated with three-dimensional conformal radiotherapy. (authors)

  20. Polarized scattered light from self-luminous exoplanets. Three-dimensional scattering radiative transfer with ARTES

    Science.gov (United States)

    Stolker, T.; Min, M.; Stam, D. M.; Mollière, P.; Dominik, C.; Waters, L. B. F. M.

    2017-11-01

    Context. Direct imaging has paved the way for atmospheric characterization of young and self-luminous gas giants. Scattering in a horizontally-inhomogeneous atmosphere causes the disk-integrated polarization of the thermal radiation to be linearly polarized, possibly detectable with the newest generation of high-contrast imaging instruments. Aims: We aim to investigate the effect of latitudinal and longitudinal cloud variations, circumplanetary disks, atmospheric oblateness, and cloud particle properties on the integrated degree and direction of polarization in the near-infrared. We want to understand how 3D atmospheric asymmetries affect the polarization signal in order to assess the potential of infrared polarimetry for direct imaging observations of planetary-mass companions. Methods: We have developed a three-dimensional Monte Carlo radiative transfer code (ARTES) for scattered light simulations in (exo)planetary atmospheres. The code is applicable to calculations of reflected light and thermal radiation in a spherical grid with a parameterized distribution of gas, clouds, hazes, and circumplanetary material. A gray atmosphere approximation is used for the thermal structure. Results: The disk-integrated degree of polarization of a horizontally-inhomogeneous atmosphere is maximal when the planet is flattened, the optical thickness of the equatorial clouds is large compared to the polar clouds, and the clouds are located at high altitude. For a flattened planet, the integrated polarization can both increase or decrease with respect to a spherical planet which depends on the horizontal distribution and optical thickness of the clouds. The direction of polarization can be either parallel or perpendicular to the projected direction of the rotation axis when clouds are zonally distributed. Rayleigh scattering by submicron-sized cloud particles will maximize the polarimetric signal whereas the integrated degree of polarization is significantly reduced with micron

  1. CT discography for cervical soft disc hernia

    Energy Technology Data Exchange (ETDEWEB)

    Iwasa, Kenichi; Mizutani, Shigeru; Morimoto, Hiroyuki; Yamada, Hidehito; Iwasa, Satoru

    1985-03-01

    In this study the effectiveness of computed tomographic discography (CTD) in diagnosing cervical soft disc hernia was evaluated. Twenty-five intervertebral discs of 15 cases with cervical soft disc hernia were examined with a discography and then a CT scan. Results of the CT scan were as follows: three discs were protruded, 12 discs were prolapsed, 6 discs were extruded, and 4 discs were sequestrated. The findings were helpful in determining the location of soft disc hernias between the median and posterolateral discs. They were also valuable in classifying types of hernias and surgical approaches.

  2. Chasing discs around O-type (proto)stars: Evidence from ALMA observations

    Science.gov (United States)

    Cesaroni, R.; Sánchez-Monge, Á.; Beltrán, M. T.; Johnston, K. G.; Maud, L. T.; Moscadelli, L.; Mottram, J. C.; Ahmadi, A.; Allen, V.; Beuther, H.; Csengeri, T.; Etoka, S.; Fuller, G. A.; Galli, D.; Galván-Madrid, R.; Goddi, C.; Henning, T.; Hoare, M. G.; Klaassen, P. D.; Kuiper, R.; Kumar, M. S. N.; Lumsden, S.; Peters, T.; Rivilla, V. M.; Schilke, P.; Testi, L.; van der Tak, F.; Vig, S.; Walmsley, C. M.; Zinnecker, H.

    2017-06-01

    Context. Circumstellar discs around massive stars could mediate the accretion onto the star from the infalling envelope, and could minimize the effects of radiation pressure. Despite such a crucial role, only a few convincing candidates have been provided for discs around deeply embedded O-type (proto)stars. Aims: In order to establish whether disc-mediated accretion is the formation mechanism for the most massive stars, we have searched for circumstellar, rotating discs around a limited sample of six luminous (>105L⊙) young stellar objects. These objects were selected on the basis of their IR and radio properties in order to maximize the likelihood of association with disc+jet systems. Methods: We used ALMA with 0.̋2 resolution to observe a large number of molecular lines typical of hot molecular cores. In this paper we limit our analysis to two disc tracers (methyl cyanide, CH3CN, and its isotopologue, 13CH3CN), and an outflow tracer (silicon monoxide, SiO). Results: We reveal many cores, although their number depends dramatically on the target. We focus on the cores that present prominent molecular line emission. In six of these a velocity gradient is seen across the core,three of which show evidence of Keplerian-like rotation. The SiO data reveal clear but poorly collimated bipolar outflow signatures towards two objects only. This can be explained if real jets are rare (perhaps short-lived) in very massive objects and/or if stellar multiplicity significantly affects the outflow structure.For all cores with velocity gradients, the velocity field is analysed through position-velocity plots to establish whether the gas is undergoing rotation with νrot ∝ R- α, as expected for Keplerian-like discs. Conclusions: Our results suggest that in three objects we are observing rotation in circumstellar discs, with three more tentative cases, and one core where no evidence for rotation is found. In all cases but one, we find that the gas mass is less than the mass of

  3. Three dimensional gel dosimetry by use of nuclear magnetic resonance imaging (MRI)

    Energy Technology Data Exchange (ETDEWEB)

    De Deene, Y; De Wagter, C; Van Duyse, B; Achten, E; De Neve, W [Ghent Rijksuniversiteit (Belgium). Kliniek voor Radiotherapie en Kerngeneeskunde; De Poorter, J [Ghent Univ. (Belgium). Dept. of Magnetic Resonance

    1995-12-01

    As co-monomers are found to polymerize by radiation, they are eligible for constructing a three dimensional dosimeter. Another kind of three dimensional dosimeter, based on the radiation sensitivity of the ferrous ions in a Fricke solution, was tested in a previous study. However, a major problem that occurs in this kind of gel dosimeters is the diffusion of the ferric and ferrous ions. The co-monomer gels are more stable. The degree of polymerisation is visualized with a clinical MRI system. Acrylamide and N,N-methylene-bis-acrylamide are dissolved in a gel composed of gelatin and water. By irradiation the co-monomers are polymerized to polyacrylamide. The gel is casted in humanoid forms. As such, a simulation of the irradiation of the patient can be performed. Magnetic resonance relaxivity images of the irradiated gel display the irradiation dose. The images of the gel are fused with the radiological images of the patient. Quantitation of the dose response of the co-monomer gel is obtained through calibration by test tubes.

  4. Three dimensional gel dosimetry by use of nuclear magnetic resonance imaging (MRI)

    International Nuclear Information System (INIS)

    De Deene, Y.; De Wagter, C.; Van Duyse, B.; Achten, E.; De Neve, W.; De Poorter, J.

    1995-01-01

    As co-monomers are found to polymerize by radiation, they are eligible for constructing a three dimensional dosimeter. Another kind of three dimensional dosimeter, based on the radiation sensitivity of the ferrous ions in a Fricke solution, was tested in a previous study. However, a major problem that occurs in this kind of gel dosimeters is the diffusion of the ferric and ferrous ions. The co-monomer gels are more stable. The degree of polymerisation is visualized with a clinical MRI system. Acrylamide and N,N-methylene-bis-acrylamide are dissolved in a gel composed of gelatin and water. By irradiation the co-monomers are polymerized to polyacrylamide. The gel is casted in humanoid forms. As such, a simulation of the irradiation of the patient can be performed. Magnetic resonance relaxivity images of the irradiated gel display the irradiation dose. The images of the gel are fused with the radiological images of the patient. Quantitation of the dose response of the co-monomer gel is obtained through calibration by test tubes

  5. Integral Dose and Radiation-Induced Secondary Malignancies: Comparison between Stereotactic Body Radiation Therapy and Three-Dimensional Conformal Radiotherapy

    Directory of Open Access Journals (Sweden)

    Stefano G. Masciullo

    2012-11-01

    Full Text Available The aim of the present paper is to compare the integral dose received by non-tumor tissue (NTID in stereotactic body radiation therapy (SBRT with modified LINAC with that received by three-dimensional conformal radiotherapy (3D-CRT, estimating possible correlations between NTID and radiation-induced secondary malignancy risk. Eight patients with intrathoracic lesions were treated with SBRT, 23 Gy × 1 fraction. All patients were then replanned for 3D-CRT, maintaining the same target coverage and applying a dose scheme of 2 Gy × 32 fractions. The dose equivalence between the different treatment modalities was achieved assuming α/β = 10Gy for tumor tissue and imposing the same biological effective dose (BED on the target (BED = 76Gy10. Total NTIDs for both techniques was calculated considering α/β = 3Gy for healthy tissue. Excess absolute cancer risk (EAR was calculated for various organs using a mechanistic model that includes fractionation effects. A paired two-tailed Student t-test was performed to determine statistically significant differences between the data (p ≤ 0.05. Our study indicates that despite the fact that for all patients integral dose is higher for SBRT treatments than 3D-CRT (p = 0.002, secondary cancer risk associated to SBRT patients is significantly smaller than that calculated for 3D-CRT (p = 0.001. This suggests that integral dose is not a good estimator for quantifying cancer induction. Indeed, for the model and parameters used, hypofractionated radiotherapy has the potential for secondary cancer reduction. The development of reliable secondary cancer risk models seems to be a key issue in fractionated radiotherapy. Further assessments of integral doses received with 3D-CRT and other special techniques are also strongly encouraged.

  6. CT discography for cervical soft disc hernia

    International Nuclear Information System (INIS)

    Iwasa, Kenichi; Mizutani, Shigeru; Morimoto, Hiroyuki; Yamada, Hidehito; Iwasa, Satoru

    1985-01-01

    In this study the effectiveness of computed tomographic discography (CTD) in diagnosing cervical soft disc hernia was evaluated. Twenty-five interververtebral discs of 15 cases with cervical soft disc hernia were examined with a discography and then a CT scan. Results of the CT scan were as follows: three discs were protruded, 12 discs were prolapsed, 6 discs were extruded, and 4 discs were sequestrated. The findings were helpful in determining the location of soft disc hernians between the median and posterolateral discs. They were also valuable in classifying types of hernians and surgical aproaches. (author)

  7. Performance evaluation of a drag-disc turbine transducer and three-beam gamma densitometer under transient two-phase flow conditions

    International Nuclear Information System (INIS)

    Nalezny, C.L.; Chen, L.L.; Solbrig, C.W.

    1979-01-01

    One of the primary variables measured in the Loss-of-Fluid Test (LOFT) Program is mass flow rate. LOFT uses drag-disc turbine tranducers (DTT) and a three-beam gamma densitometer to measure parameters from which mass flow may be computed. The transducer combination was performance tested under transient conditions in the blowdown loop at the LOFT Test Support Facility (LTSF). The performance tests consisted of three partial blowdowns of different durations starting from the same initial conditions. The reference mean mass flow rate was determined by measuring the amount of water required to reestablish initial conditions after each partial blowdown. The average mass flow rates computed from the output of the drag disc, turbine, and gamma densitometer were compared to the reference mean mass flow rates over three blowdown intervals. The tests indicated that the equal phase velocity mass measurement model provided excellent results through the use of the turbine and densitometer, and drag disc and densitometer when the phase velocities were nearly equal

  8. Ex vivo cultures of glioblastoma in three-dimensional hydrogel maintain the original tumor growth behavior and are suitable for preclinical drug and radiation sensitivity screening

    Energy Technology Data Exchange (ETDEWEB)

    Jiguet Jiglaire, Carine, E-mail: carine.jiguet-jiglaire@univ-amu.fr [Aix Marseille Université, Faculté de Médecine de la Timone, 27 boulevard Jean Moulin, 13284 Marseille (France); CRO2, UMR 911, Faculté de Médecine de la Timone, 27 boulevard Jean Moulin, 13284 Marseille Cedex (France); INSERM, U911, 13005 Marseille (France); Baeza-Kallee, Nathalie; Denicolaï, Emilie; Barets, Doriane [Aix Marseille Université, Faculté de Médecine de la Timone, 27 boulevard Jean Moulin, 13284 Marseille (France); CRO2, UMR 911, Faculté de Médecine de la Timone, 27 boulevard Jean Moulin, 13284 Marseille Cedex (France); INSERM, U911, 13005 Marseille (France); Metellus, Philippe [Aix Marseille Université, Faculté de Médecine de la Timone, 27 boulevard Jean Moulin, 13284 Marseille (France); CRO2, UMR 911, Faculté de Médecine de la Timone, 27 boulevard Jean Moulin, 13284 Marseille Cedex (France); INSERM, U911, 13005 Marseille (France); APHM, Timone Hospital, Department of Neurosurgery, 13005 Marseille (France); Timone Hospital, 264 Rue Saint Pierre, 13385 Marseille Cedex 5 (France); and others

    2014-02-15

    Identification of new drugs and predicting drug response are major challenges in oncology, especially for brain tumors, because total surgical resection is difficult and radiation therapy or chemotherapy is often ineffective. With the aim of developing a culture system close to in vivo conditions for testing new drugs, we characterized an ex vivo three-dimensional culture system based on a hyaluronic acid-rich hydrogel and compared it with classical two-dimensional culture conditions. U87-MG glioblastoma cells and seven primary cell cultures of human glioblastomas were subjected to radiation therapy and chemotherapy drugs. It appears that 3D hydrogel preserves the original cancer growth behavior and enables assessment of the sensitivity of malignant gliomas to radiation and drugs with regard to inter-tumoral heterogeneity of therapeutic response. It could be used for preclinical assessment of new therapies. - Highlights: • We have compared primary glioblastoma cell culture in a 2D versus 3D-matrix system. • In 3D morphology, organization and markers better recapitulate the original tumor. • 3D-matrix culture might represent a relevant system for more accurate drug screening.

  9. Ex vivo cultures of glioblastoma in three-dimensional hydrogel maintain the original tumor growth behavior and are suitable for preclinical drug and radiation sensitivity screening

    International Nuclear Information System (INIS)

    Jiguet Jiglaire, Carine; Baeza-Kallee, Nathalie; Denicolaï, Emilie; Barets, Doriane; Metellus, Philippe

    2014-01-01

    Identification of new drugs and predicting drug response are major challenges in oncology, especially for brain tumors, because total surgical resection is difficult and radiation therapy or chemotherapy is often ineffective. With the aim of developing a culture system close to in vivo conditions for testing new drugs, we characterized an ex vivo three-dimensional culture system based on a hyaluronic acid-rich hydrogel and compared it with classical two-dimensional culture conditions. U87-MG glioblastoma cells and seven primary cell cultures of human glioblastomas were subjected to radiation therapy and chemotherapy drugs. It appears that 3D hydrogel preserves the original cancer growth behavior and enables assessment of the sensitivity of malignant gliomas to radiation and drugs with regard to inter-tumoral heterogeneity of therapeutic response. It could be used for preclinical assessment of new therapies. - Highlights: • We have compared primary glioblastoma cell culture in a 2D versus 3D-matrix system. • In 3D morphology, organization and markers better recapitulate the original tumor. • 3D-matrix culture might represent a relevant system for more accurate drug screening

  10. Ultrastructure of inclusion bodies in annulus cells in the degenerating human intervertebral disc.

    Science.gov (United States)

    Gruber, H E; Hanley, E N

    2009-06-01

    The rough endoplasmic reticulum (rER) of the cell has an architectural editing function that checks whether protein structure and three-dimensional assembly have occurred properly prior to export of newly synthesized material out of the cell. If these have been faulty, the material is retained within the rER as an inclusion body. Inclusion bodies have been identified previously in chondrocytes and osteoblasts in chondrodysplasias and osteogenesis imperfecta. Inclusion bodies in intervertebral disc cells, however, have only recently been recognized. Our objectives were to use transmission electron microscopy to analyze more fully inclusion bodies in the annulus pulposus and to study the extracellular matrix (ECM) surrounding cells containing inclusion bodies. ECM frequently encapsulated cells with inclusion bodies, and commonly contained prominent banded aggregates of Type VI collagen. Inclusion body material had several morphologies, including relatively smooth, homogeneous material, or a rougher, less homogeneous feature. Such findings expand our knowledge of the fine structure of the human disc cell and ECM during disc degeneration, and indicate the potential utility of ultrastructural identification of discs with intracellular inclusion bodies as a screening method for molecular studies directed toward identification of defective gene products in degenerating discs.

  11. Human umbilical cord mesenchymal stromal cells exhibit immature nucleus pulposus cell phenotype in a laminin-rich pseudo-three-dimensional culture system.

    Science.gov (United States)

    Chon, Brian H; Lee, Esther J; Jing, Liufang; Setton, Lori A; Chen, Jun

    2013-10-02

    Cell supplementation to the herniated or degenerated intervertebral disc (IVD) is a potential strategy to promote tissue regeneration and slow disc pathology. Human umbilical cord mesenchymal stromal cells (HUCMSCs) - originating from the Wharton's jelly - remain an attractive candidate for such endeavors with their ability to differentiate into multiple lineages. Previously, mesenchymal stem cells (MSCs) have been studied as a potential source for disc tissue regeneration. However, no studies have demonstrated that MSCs can regenerate matrix with unique characteristics matching that of immature nucleus pulposus (NP) tissues of the IVD. In our prior work, immature NP cells were found to express specific laminin isoforms and laminin-binding receptors that may serve as phenotypic markers for evaluating MSC differentiation to NP-like cells. The goal of this study is to evaluate these markers and matrix synthesis for HUCMSCs cultured in a laminin-rich pseudo-three-dimensional culture system. HUCMSCs were seeded on top of Transwell inserts pre-coated with Matrigel™, which contained mainly laminin-111. Cells were cultured under hypoxia environment with three differentiation conditions: NP differentiation media (containing 2.5% Matrigel™ solution to provide for a pseudo-three-dimensional laminin culture system) with no serum, or the same media supplemented with either insulin-like growth factor-1 (IGF-1) or transforming growth factor-β1 (TGF-β1). Cell clustering behavior, matrix production and the expression of NP-specific laminin and laminin-receptors were evaluated at days 1, 7, 13 and 21 of culture. Data show that a pseudo-three-dimensional culture condition (laminin-1 rich) promoted HUCMSC differentiation under no serum conditions. Starting at day 1, HUCMSCs demonstrated a cell clustering morphology similar to that of immature NP cells in situ and that observed for primary immature NP cells within the similar laminin-rich culture system (prior study

  12. Quality Assurance Challenges for Motion-Adaptive Radiation Therapy: Gating, Breath Holding, and Four-Dimensional Computed Tomography

    International Nuclear Information System (INIS)

    Jiang, Steve B.; Wolfgang, John; Mageras, Gig S.

    2008-01-01

    Compared with conventional three-dimensional (3D) conformal radiation therapy and intensity-modulated radiation therapy treatments, quality assurance (QA) for motion-adaptive radiation therapy involves various challenges because of the added temporal dimension. Here we discuss those challenges for three specific techniques related to motion-adaptive therapy: namely respiratory gating, breath holding, and four-dimensional computed tomography. Similar to the introduction of any other new technologies in clinical practice, typical QA measures should be taken for these techniques also, including initial testing of equipment and clinical procedures, as well as frequent QA examinations during the early stage of implementation. Here, rather than covering every QA aspect in depth, we focus on some major QA challenges. The biggest QA challenge for gating and breath holding is how to ensure treatment accuracy when internal target position is predicted using external surrogates. Recommended QA measures for each component of treatment, including simulation, planning, patient positioning, and treatment delivery and verification, are discussed. For four-dimensional computed tomography, some major QA challenges have also been discussed

  13. Upregulated epidermal growth factor receptor expression following near-infrared irradiation simulating solar radiation in a three-dimensional reconstructed human corneal epithelial tissue culture model.

    Science.gov (United States)

    Tanaka, Yohei; Nakayama, Jun

    2016-01-01

    Humans are increasingly exposed to near-infrared (NIR) radiation from both natural (eg, solar) and artificial (eg, electrical appliances) sources. Although the biological effects of sun and ultraviolet (UV) exposure have been extensively investigated, the biological effect of NIR radiation is still unclear. We previously reported that NIR as well as UV induces photoaging and standard UV-blocking materials, such as sunglasses, do not sufficiently block NIR. The objective of this study was to investigate changes in gene expression in three-dimensional reconstructed corneal epithelial tissue culture exposed to broad-spectrum NIR irradiation to simulate solar NIR radiation that reaches human tissues. DNA microarray and quantitative real-time polymerase chain reaction analysis were used to assess gene expression levels in a three-dimensional reconstructed corneal epithelial model composed of normal human corneal epithelial cells exposed to water-filtered broad-spectrum NIR irradiation with a contact cooling (20°C). The water-filter allowed 1,000-1,800 nm wavelengths and excluded 1,400-1,500 nm wavelengths. A DNA microarray with >62,000 different probes showed 25 and 150 genes that were up- or downregulated by at least fourfold and twofold, respectively, after NIR irradiation. In particular, epidermal growth factor receptor (EGFR) was upregulated by 19.4-fold relative to control cells. Quantitative real-time polymerase chain reaction analysis revealed that two variants of EGFR in human corneal epithelial tissue were also significantly upregulated after five rounds of 10 J/cm(2) irradiation (Psolar energy reaching the Earth is in the NIR region, which cannot be adequately blocked by eyewear and thus can induce eye damage with intensive or long-term exposure, protection from both UV and NIR radiation may prevent changes in gene expression and in turn eye damage.

  14. Three-dimensional particle image velocimetry measurement technique

    International Nuclear Information System (INIS)

    Hassan, Y.A.; Seeley, C.H.; Henderson, J.A.; Schmidl, W.D.

    2004-01-01

    The experimental flow visualization tool, Particle Image Velocimetry (PIV), is being used to determine the velocity field in two-dimensional fluid flows. In the past few years, the technique has been improved to allow the capture of flow fields in three dimensions. This paper describes changes which were made to two existing two-dimensional tracking algorithms to enable them to track three-dimensional PIV data. Results of the tests performed on these three-dimensional routines with synthetic data are presented. Experimental data was also used to test the tracking algorithms. The test setup which was used to acquire the three-dimensional experimental data is described, along with the results from both of the tracking routines which were used to analyze the experimental data. (author)

  15. Do three-dimensional reconstructions add to the diagnostic value of computed tomography in the field of traumatology?

    International Nuclear Information System (INIS)

    Billet, F.P.J.; Schmitt, W.G.H.; Hofmann, M.; Huber, M.; Gay, B.

    1990-01-01

    Very little time was needed for three-dimensional techniques to show that they are of great importance to the accurracy and, above all, interpretation of CT-based diagnostic findings in the skeleton. This method is not associated with any increased risks from radiation and if there is no absolute requirement for a 'second plane' to be displayed, as for instance in fractures of the calcaneus, radiation exposure can be reduced even further. Particular mention should here also be made of the sternoclavicular joint, coracoid process and intervertebral foramina, even more so as we feel that the diagnostic advantages offered by three-dimensional techniques in traumatology have so far not been described in sufficient detail. (orig./GDG) [de

  16. Fractionated, three-dimensional, planning-assisted proton-radiation therapy for orbital rhabdomyosarcoma: a novel technique

    International Nuclear Information System (INIS)

    Hug, Eugen B.; Adams, Judy; Fitzek, Markus; Vries, Alexander de; Munzenrider, John E.

    2000-01-01

    Purpose: Most children with orbital rhabdomyosarcoma will survive their disease. However, conventional photon-radiation treatment, as part of multimodality therapy, results in varying degrees of long-term functional and cosmetic side effects. This report introduces external beam proton radiation therapy (PRT) as a conformal, three-dimensional planned radiation technique for this disease, analyzes normal tissue dosimetry, and describes the technique's application in the first 2 patients. Material and Methods: Between January 1995 and February 1996, 2 patients underwent PRT following biopsy and chemotherapy for orbital rhabdomyosarcoma. Fifty and 55 Cobalt Gray Equivalent (CGE) were delivered to the gross tumor volume and 40 CGE to clinical target volumes in both patients. A relative biologic effectiveness (RBE) of 1.1 was utilized to correlate proton dose calculations with CGE. To achieve dose conformity, a ''patch technique'' was utilized, where target regions were divided into segments, each treated by a separate proton field. Dose-volume histograms were obtained for target and nontarget regions, including lens, bony orbit, pituitary gland, optic chiasm, optic nerves, lacrimal gland, and ipsilateral frontal and temporal lobes. Results: At 3.4 and 2.5 years after PRT, both patients are clinically and radiographically free of disease. Visual acuity remains excellent, without signs of cataract formation; pituitary function is normal; cosmetically, only mild enophthalmos is noticeable. Doses to 90%, 50%, and 5% of lens volume were kept at less than 1%, less than 2%, and less than 8%, respectively. Fifty percent of lacrimal gland volume received less than 36% of the prescribed dose and 50% of the volume of the optic chiasm, pituitary gland, and hypothalamus were restricted to less than 2%. Proton conformity to orbital contents resulted in between 9% and 36% of the prescribed dose reaching the ipsilateral temporal and frontal lobes immediately adjacent to bony orbit (5

  17. Piezoelectric transducer vibrations in a one-dimensional approximation

    CERN Document Server

    Hilke, H J

    1973-01-01

    The theory of piezoelectric transducer vibrations, which may be treated as one-dimensional, is developed in detail for thin discs vibrating in a pure thickness extensional mode. An effort has been made to obtain relations of general validity, which include losses, and which are in a simple explicit form convenient for practical calculations. The behaviour of transducers is discussed with special attention to their characteristics at the two fundamental frequencies, the so-called parallel and series resonances. Several peculiarities occur when transducers are coupled to media with considerably different acoustic impedances. These peculiarities are discussed and illustrated by numerical results for quartz and PZT 4 piezoelectric discs radiating into water, air and liquid hydrogen. The application of the theory to different types of vibrations is briefly illustrated for thin bars vibrating longitudinally. Short discussions are included on compound transducer systems, and on the properties of thin discs as receiv...

  18. Three-dimensional inhomogeneous rain fields: implications for the distribution of intensity and polarization of the microwave thermal radiation.

    Science.gov (United States)

    Ilyushin, Yaroslaw; Kutuza, Boris

    Observations and mapping of the upwelling thermal radiation of the Earth is the very promising remote sensing technique for the global monitoring of the weather and precipitations. For reliable interpretation of the observation data, numerical model of the microwave radiative transfer in the precipitating atmosphere is necessary. In the present work, numerical simulations of thermal microwave radiation in the rain have been performed at three wavelengths (3, 8 and 22 mm). Radiative properties of the rain have been simulated using public accessible T-matrix codes (Mishchenko, Moroz) for non-spherical particles of fixed orientation and realistic raindrop size distributions (Marshall-Palmer) within the range of rain intensity 1-100 mm/h. Thermal radiation of infinite flat slab medium and isolated rain cell of kilometer size has been simulated with finite difference scheme for the vectorial radiative transfer equation (VRTE) in dichroic scattering medium. Principal role of cell structure of the rain field in the formation of angular and spatial distribution of the intensity and polarization of the upwelling thermal radiation has been established. Possible approaches to interpretation of satellite data are also discussed. It is necessary that spatial resolution of microwave radiometers be less than rain cell size. At the present time the resolution is approximately 15 km. It can be considerably improved, for example by two-dimensional synthetic aperture millimeter-wave radiometric interferometer for measuring full-component Stokes vector of emission from hydrometeors. The estimates show that in millimeter band it is possible to develop such equipment with spatial resolution of the order of 1-2 km, which is significantly less than the size of rain cell, with sensitivity 0.3-0.5 K. Under this condition the second Stokes parameter may by successfully measured and may be used for investigation of precipitation regions. Y-shaped phased array antenna is the most promising to

  19. Structures of two-dimensional three-body systems

    International Nuclear Information System (INIS)

    Ruan, W.Y.; Liu, Y.Y.; Bao, C.G.

    1996-01-01

    Features of the structure of L = 0 states of a two-dimensional three-body model system have been investigated. Three types of permutation symmetry of the spatial part, namely symmetric, antisymmetric, and mixed, have been considered. A comparison has been made between the two-dimensional system and the corresponding three-dimensional one. The effect of symmetry on microscopic structures is emphasized. (author)

  20. Three-dimensional temperature history of a multipass filled weldment. Part 2

    International Nuclear Information System (INIS)

    Pinkowish, J.A.; Whitman, P.K.

    1976-01-01

    Computer simulation of the three-dimensional temperature history in a multipass filled weldment was attempted by modifying a transient heat transfer code, HEATING5. The model includes temperature-dependent physical parameters, radiation and convection heat losses, turbulent and laminar convection in the molten pool, and variable arc velocity, intensity, and weld geometry. The model requires approximately 28 CPU min to simulate one second of welding. 15 figures, 8 tables

  1. Distribution of stress on TMJ disc induced by use of chincup therapy: assessment by the finite element method

    Science.gov (United States)

    Calçada, Flávio Siqueira; Guimarães, Antônio Sérgio; Teixeira, Marcelo Lucchesi; Takamatsu, Flávio Atsushi

    2017-01-01

    ABSTRACT Objective: To assess the distribution of stress produced on TMJ disc by chincup therapy, by means of the finite element method. Methods: a simplified three-dimensional TMJ disc model was developed by using Rhinoceros 3D software, and exported to ANSYS software. A 4.9N load was applied on the inferior surface of the model at inclinations of 30, 40, and 50 degrees to the mandibular plane (GoMe). ANSYS was used to analyze stress distribution on the TMJ disc for the different angulations, by means of finite element method. Results: The results showed that the tensile and compressive stresses concentrations were higher on the inferior surface of the model. More presence of tensile stress was found in the middle-anterior region of the model and its location was not altered in the three directions of load application. There was more presence of compressive stress in the middle and mid-posterior regions, but when a 50o inclined load was applied, concentration in the middle region was prevalent. Tensile and compressive stresses intensities progressively diminished as the load was more vertically applied. Conclusions: stress induced by the chincup therapy is mainly located on the inferior surface of the model. Loads at greater angles to the mandibular plane produced distribution of stresses with lower intensity and a concentration of compressive stresses in the middle region. The simplified three-dimensional model proved useful for assessing the distribution of stresses on the TMJ disc induced by the chincup therapy. PMID:29160348

  2. Elastocapillary fabrication of three-dimensional microstructures

    NARCIS (Netherlands)

    van Honschoten, J.W.; Berenschot, Johan W.; Ondarcuhu, T.; Sanders, Remco G.P.; Sundaram, J.; Elwenspoek, Michael Curt; Tas, Niels Roelof

    2010-01-01

    We describe the fabrication of three-dimensional microstructures by means of capillary forces. Using an origami-like technique, planar silicon nitride structures of various geometries are folded to produce three-dimensional objects of 50–100 m. Capillarity is a particularly effective mechanism since

  3. Application of three-dimensional computed tomography in craniofacial clinical practice and research.

    Science.gov (United States)

    Anderson, P J; Yong, R; Surman, T L; Rajion, Z A; Ranjitkar, S

    2014-06-01

    Following the invention of the first computed tomography (CT) scanner in the early 1970s, many innovations in three-dimensional (3D) diagnostic imaging technology have occurred, leading to a wide range of applications in craniofacial clinical practice and research. Three-dimensional image analysis provides superior and more detailed information compared with conventional plain two-dimensional (2D) radiography, with the added benefit of 3D printing for preoperative treatment planning and regenerative therapy. Current state-of-the-art multidetector CT (MDCT), also known as medical CT, has an important role in the diagnosis and management of craniofacial injuries and pathology. Three-dimensional cone beam CT (CBCT), pioneered in the 1990s, is gaining increasing popularity in dental and craniofacial clinical practice because of its faster image acquisition at a lower radiation dose, but sound guidelines are needed to ensure its optimal clinical use. Recent innovations in micro-computed tomography (micro-CT) have revolutionized craniofacial biology research by enabling higher resolution scanning of teeth beyond the capabilities of MDCT and CBCT, presenting new prospects for translational clinical research. Even after four decades of refinement, CT technology continues to advance and broaden the horizons of craniofacial clinical practice and phenomics research. © 2014 Australian Dental Association.

  4. Disc-halo interactions in ΛCDM

    Science.gov (United States)

    Bauer, Jacob S.; Widrow, Lawrence M.; Erkal, Denis

    2018-05-01

    We present a new method for embedding a stellar disc in a cosmological dark matter halo and provide a worked example from a Λ cold dark matter zoom-in simulation. The disc is inserted into the halo at a redshift z = 3 as a zero-mass rigid body. Its mass and size are then increased adiabatically while its position, velocity, and orientation are determined from rigid-body dynamics. At z = 1, the rigid disc (RD) is replaced by an N-body disc whose particles sample a three-integral distribution function (DF). The simulation then proceeds to z = 0 with live disc (LD) and halo particles. By comparison, other methods assume one or more of the following: the centre of the RD during the growth phase is pinned to the minimum of the halo potential, the orientation of the RD is fixed, or the live N-body disc is constructed from a two rather than three-integral DF. In general, the presence of a disc makes the halo rounder, more centrally concentrated, and smoother, especially in the innermost regions. We find that methods in which the disc is pinned to the minimum of the halo potential tend to overestimate the amount of adiabatic contraction. Additionally, the effect of the disc on the subhalo distribution appears to be rather insensitive to the disc insertion method. The LD in our simulation develops a bar that is consistent with the bars seen in late-type spiral galaxies. In addition, particles from the disc are launched or `kicked up' to high galactic latitudes.

  5. Three-dimensional printing and pediatric liver disease.

    Science.gov (United States)

    Alkhouri, Naim; Zein, Nizar N

    2016-10-01

    Enthusiastic physicians and medical researchers are investigating the role of three-dimensional printing in medicine. The purpose of the current review is to provide a concise summary of the role of three-dimensional printing technology as it relates to the field of pediatric hepatology and liver transplantation. Our group and others have recently demonstrated the feasibility of printing three-dimensional livers with identical anatomical and geometrical landmarks to the native liver to facilitate presurgical planning of complex liver surgeries. Medical educators are exploring the use of three-dimensional printed organs in anatomy classes and surgical residencies. Moreover, mini-livers are being developed by regenerative medicine scientist as a way to test new drugs and, eventually, whole livers will be grown in the laboratory to replace organs with end-stage disease solving the organ shortage problem. From presurgical planning to medical education to ultimately the bioprinting of whole organs for transplantation, three-dimensional printing will change medicine as we know in the next few years.

  6. Instability of warped discs

    Science.gov (United States)

    Doǧan, S.; Nixon, C. J.; King, A. R.; Pringle, J. E.

    2018-05-01

    Accretion discs are generally warped. If a warp in a disc is too large, the disc can `break' apart into two or more distinct planes, with only tenuous connections between them. Further, if an initially planar disc is subject to a strong differential precession, then it can be torn apart into discrete annuli that precess effectively independently. In previous investigations, torque-balance formulae have been used to predict where and when the disc breaks into distinct parts. In this work, focusing on discs with Keplerian rotation and where the shearing motions driving the radial communication of the warp are damped locally by turbulence (the `diffusive' regime), we investigate the stability of warped discs to determine the precise criterion for an isolated warped disc to break. We find and solve the dispersion relation, which, in general, yields three roots. We provide a comprehensive analysis of this viscous-warp instability and the emergent growth rates and their dependence on disc parameters. The physics of the instability can be understood as a combination of (1) a term that would generally encapsulate the classical Lightman-Eardley instability in planar discs (given by ∂(νΣ)/∂Σ < 0) but is here modified by the warp to include ∂(ν1|ψ|)/∂|ψ| < 0, and (2) a similar condition acting on the diffusion of the warp amplitude given in simplified form by ∂(ν2|ψ|)/∂|ψ| < 0. We discuss our findings in the context of discs with an imposed precession, and comment on the implications for different astrophysical systems.

  7. Imbalanced Protein Expression Patterns of Anabolic, Catabolic, Anti-Catabolic and Inflammatory Cytokines in Degenerative Cervical Disc Cells: New Indications for Gene Therapeutic Treatments of Cervical Disc Diseases

    Science.gov (United States)

    Mern, Demissew S.; Beierfuß, Anja; Fontana, Johann; Thomé, Claudius; Hegewald, Aldemar A.

    2014-01-01

    Degenerative disc disease (DDD) of the cervical spine is common after middle age and can cause loss of disc height with painful nerve impingement, bone and joint inflammation. Despite the clinical importance of these problems, in current publications the pathology of cervical disc degeneration has been studied merely from a morphologic view point using magnetic resonance imaging (MRI), without addressing the issue of biological treatment approaches. So far a wide range of endogenously expressed bioactive factors in degenerative cervical disc cells has not yet been investigated, despite its importance for gene therapeutic approaches. Although degenerative lumbar disc cells have been targeted by different biological treatment approaches, the quantities of disc cells and the concentrations of gene therapeutic factors used in animal models differ extremely. These indicate lack of experimentally acquired data regarding disc cell proliferation and levels of target proteins. Therefore, we analysed proliferation and endogenous expression levels of anabolic, catabolic, ant-catabolic, inflammatory cytokines and matrix proteins of degenerative cervical disc cells in three-dimensional cultures. Preoperative MRI grading of cervical discs was used, then grade III and IV nucleus pulposus (NP) tissues were isolated from 15 patients, operated due to cervical disc herniation. NP cells were cultured for four weeks with low-glucose in collagen I scaffold. Their proliferation rates were analysed using 3-(4, 5-dimethylthiazolyl-2)-2,5-diphenyltetrazolium bromide. Their protein expression levels of 28 therapeutic targets were analysed using enzyme-linked immunosorbent assay. During progressive grades of degeneration NP cell proliferation rates were similar. Significantly decreased aggrecan and collagen II expressions (P<0.0001) were accompanied by accumulations of selective catabolic and inflammatory cytokines (disintegrin and metalloproteinase with thrombospondin motifs 4 and 5, matrix

  8. Visual Interpretation with Three-Dimensional Annotations (VITA): Three-Dimensional Image Interpretation Tool for Radiological Reporting

    OpenAIRE

    Roy, Sharmili; Brown, Michael S.; Shih, George L.

    2013-01-01

    This paper introduces a software framework called Visual Interpretation with Three-Dimensional Annotations (VITA) that is able to automatically generate three-dimensional (3D) visual summaries based on radiological annotations made during routine exam reporting. VITA summaries are in the form of rotating 3D volumes where radiological annotations are highlighted to place important clinical observations into a 3D context. The rendered volume is produced as a Digital Imaging and Communications i...

  9. Radiative transfer in disc galaxies - V. The accuracy of the KB approximation

    Science.gov (United States)

    Lee, Dukhang; Baes, Maarten; Seon, Kwang-Il; Camps, Peter; Verstocken, Sam; Han, Wonyong

    2016-12-01

    We investigate the accuracy of an approximate radiative transfer technique that was first proposed by Kylafis & Bahcall (hereafter the KB approximation) and has been popular in modelling dusty late-type galaxies. We compare realistic galaxy models calculated with the KB approximation with those of a three-dimensional Monte Carlo radiative transfer code SKIRT. The SKIRT code fully takes into account of the contribution of multiple scattering whereas the KB approximation calculates only single scattered intensity and multiple scattering components are approximated. We find that the KB approximation gives fairly accurate results if optically thin, face-on galaxies are considered. However, for highly inclined (I ≳ 85°) and/or optically thick (central face-on optical depth ≳1) galaxy models, the approximation can give rise to substantial errors, sometimes, up to ≳40 per cent. Moreover, it is also found that the KB approximation is not always physical, sometimes producing infinite intensities at lines of sight with high optical depth in edge-on galaxy models. There is no `simple recipe' to correct the errors of the KB approximation that is universally applicable to any galaxy models. Therefore, it is recommended that the full radiative transfer calculation be used, even though it is slower than the KB approximation.

  10. Advanced concepts in multi-dimensional radiation detection and imaging

    International Nuclear Information System (INIS)

    Vetter, Kai; Barnowski, Ross; Pavlovsky, Ryan; Haefner, Andy; Torii, Tatsuo; Shikaze, Yoshiaki; Sanada, Yukihisa

    2016-01-01

    Recent developments in the detector fabrication, signal readout, and data processing enable new concepts in radiation detection that are relevant for applications ranging from fundamental physics to medicine as well as nuclear security and safety. We present recent progress in multi-dimensional radiation detection and imaging in the Berkeley Applied Nuclear Physics program. It is based on the ability to reconstruct scenes in three dimensions and fuse it with gamma-ray image information. We are using the High-Efficiency Multimode Imager HEMI in its Compton imaging mode and combining it with contextual sensors such as the Microsoft Kinect or visual cameras. This new concept of volumetric imaging or scene data fusion provides unprecedented capabilities in radiation detection and imaging relevant for the detection and mapping of radiological and nuclear materials. This concept brings us one step closer to the seeing the world with gamma-ray eyes. (author)

  11. Culture of three-dimensional tissue model and its application in bystander-effect research

    International Nuclear Information System (INIS)

    Wu Ruqun; Xu An; Wu Lijun; Hu Burong

    2012-01-01

    Compared with the cultured monolayer (2D) cells, three-dimensional (3D) tissue could be more similar to the environment in vivo including the physical support, chemical factors, cell-cell and cell-matrix interaction and so on. With the development of three-dimensional cell culture techniques (TDCC), 3D tissue is widely used in the areas of bystander effect research. This review focuses on introducing the TDCC method and its application in bystander-effect research. First, the development process of 3D tissue culture method was introduced. Secondly, the induction of radiation induced bystander effects both in 2D cell and 3D tissue and its mechanisms were reviewed. Finally, because heavy ion (carbon ion beam) has been developed as a useful tool to cure solid cancer, and the 3D tissue model is an ideal material to study the damages on body after being irradiated and to understand the underlying mechanisms, future study about heavy ion radiation inducing bystander effect in 3D tissue was discussed. (authors)

  12. Three-dimensional reconstruction of functional brain images

    International Nuclear Information System (INIS)

    Inoue, Masato; Shoji, Kazuhiko; Kojima, Hisayoshi; Hirano, Shigeru; Naito, Yasushi; Honjo, Iwao

    1999-01-01

    We consider PET (positron emission tomography) measurement with SPM (Statistical Parametric Mapping) analysis to be one of the most useful methods to identify activated areas of the brain involved in language processing. SPM is an effective analytical method that detects markedly activated areas over the whole brain. However, with the conventional presentations of these functional brain images, such as horizontal slices, three directional projection, or brain surface coloring, makes understanding and interpreting the positional relationships among various brain areas difficult. Therefore, we developed three-dimensionally reconstructed images from these functional brain images to improve the interpretation. The subjects were 12 normal volunteers. The following three types of images were constructed: routine images by SPM, three-dimensional static images, and three-dimensional dynamic images, after PET images were analyzed by SPM during daily dialog listening. The creation of images of both the three-dimensional static and dynamic types employed the volume rendering method by VTK (The Visualization Toolkit). Since the functional brain images did not include original brain images, we synthesized SPM and MRI brain images by self-made C++ programs. The three-dimensional dynamic images were made by sequencing static images with available software. Images of both the three-dimensional static and dynamic types were processed by a personal computer system. Our newly created images showed clearer positional relationships among activated brain areas compared to the conventional method. To date, functional brain images have been employed in fields such as neurology or neurosurgery, however, these images may be useful even in the field of otorhinolaryngology, to assess hearing and speech. Exact three-dimensional images based on functional brain images are important for exact and intuitive interpretation, and may lead to new developments in brain science. Currently, the surface

  13. Three-dimensional reconstruction of functional brain images

    Energy Technology Data Exchange (ETDEWEB)

    Inoue, Masato; Shoji, Kazuhiko; Kojima, Hisayoshi; Hirano, Shigeru; Naito, Yasushi; Honjo, Iwao [Kyoto Univ. (Japan)

    1999-08-01

    We consider PET (positron emission tomography) measurement with SPM (Statistical Parametric Mapping) analysis to be one of the most useful methods to identify activated areas of the brain involved in language processing. SPM is an effective analytical method that detects markedly activated areas over the whole brain. However, with the conventional presentations of these functional brain images, such as horizontal slices, three directional projection, or brain surface coloring, makes understanding and interpreting the positional relationships among various brain areas difficult. Therefore, we developed three-dimensionally reconstructed images from these functional brain images to improve the interpretation. The subjects were 12 normal volunteers. The following three types of images were constructed: routine images by SPM, three-dimensional static images, and three-dimensional dynamic images, after PET images were analyzed by SPM during daily dialog listening. The creation of images of both the three-dimensional static and dynamic types employed the volume rendering method by VTK (The Visualization Toolkit). Since the functional brain images did not include original brain images, we synthesized SPM and MRI brain images by self-made C++ programs. The three-dimensional dynamic images were made by sequencing static images with available software. Images of both the three-dimensional static and dynamic types were processed by a personal computer system. Our newly created images showed clearer positional relationships among activated brain areas compared to the conventional method. To date, functional brain images have been employed in fields such as neurology or neurosurgery, however, these images may be useful even in the field of otorhinolaryngology, to assess hearing and speech. Exact three-dimensional images based on functional brain images are important for exact and intuitive interpretation, and may lead to new developments in brain science. Currently, the surface

  14. Three-Dimensional Non-Coplanar Conformal Radiotherapy Yields Better Results Than Traditional Beam Arrangements for Adjuvant Treatment of Gastric Cancer

    International Nuclear Information System (INIS)

    Soyfer, Viacheslav; Corn, Benjamin W.; Melamud, Alex B.S.; Alani, Shlomi; Tempelhof, Haim; Agai, Reuben; Shmueli, Anat; Figer, Arie; Kovner, Felix

    2007-01-01

    Purpose: The current standard of adjuvant treatment for gastric cancer after curative resection is concurrent administration of radiotherapy and 5-fluorouracil-based chemotherapy. The radiation fields are often arranged as anterioposterior-posteroanterior opposed parallel fields with general recommendations for sparing at least two-thirds of one kidney. We investigated whether a better radiation distribution would be achievable with three-dimensional conformal approaches compared with the classic anterioposterior-posteroanterior fields. Methods and Materials: A total of 19 patients with adenocarcinoma of the stomach were treated with adjuvant chemoradiotherapy using a non-coplanar four-field arrangement. In each case, parallel planning using an anterioposterior-posteroanterior arrangement and a four-field 'box' was performed, and the generated plans were subsequently compared for coverage of target volumes and doses to irradiated organs next to the tumor bed. A separate analysis was performed for kidneys exposed to greater and lower doses in each patient. The mean radiation dose and percentage of kidney volume receiving a dose >20 Gy were registered. Statistical analysis was performed using the two-tailed t test. Results: The clinical target volume was adequately covered in all three plans. In the greater-dose kidney group, all the differences were statistically significant with a benefit for the three-dimensional plan. In the lower-dose kidney group, the differences in the mean radiation dose did not reach the level of statistical significance, and the differences in the kidney volume receiving a dose >20 Gy showed a statistically significant benefit for the three-dimensional plan. Conclusion: Non-coplanar three-dimensional-based conformal planning for postoperative radiotherapy for gastric cancer provided the best results regarding kidney and spinal cord exposure with adequate clinical target volume coverage. This technique was readily implemented in clinical

  15. Three-dimensional non-coplanar conformal radiotherapy yields better results than traditional beam arrangements for adjuvant treatment of gastric cancer.

    Science.gov (United States)

    Soyfer, Viacheslav; Corn, Benjamin W; Melamud, Alex; Alani, Shlomi; Tempelhof, Haim; Agai, Reuben; Shmueli, Anat; Figer, Arie; Kovner, Felix

    2007-10-01

    The current standard of adjuvant treatment for gastric cancer after curative resection is concurrent administration of radiotherapy and 5-fluorouracil-based chemotherapy. The radiation fields are often arranged as anterioposterior-posteroanterior opposed parallel fields with general recommendations for sparing at least two-thirds of one kidney. We investigated whether a better radiation distribution would be achievable with three-dimensional conformal approaches compared with the classic anterioposterior-posteroanterior fields. A total of 19 patients with adenocarcinoma of the stomach were treated with adjuvant chemoradiotherapy using a non-coplanar four-field arrangement. In each case, parallel planning using an anterioposterior-posteroanterior arrangement and a four-field "box" was performed, and the generated plans were subsequently compared for coverage of target volumes and doses to irradiated organs next to the tumor bed. A separate analysis was performed for kidneys exposed to greater and lower doses in each patient. The mean radiation dose and percentage of kidney volume receiving a dose >20 Gy were registered. Statistical analysis was performed using the two-tailed t test. The clinical target volume was adequately covered in all three plans. In the greater-dose kidney group, all the differences were statistically significant with a benefit for the three-dimensional plan. In the lower-dose kidney group, the differences in the mean radiation dose did not reach the level of statistical significance, and the differences in the kidney volume receiving a dose >20 Gy showed a statistically significant benefit for the three-dimensional plan. Non-coplanar three-dimensional-based conformal planning for postoperative radiotherapy for gastric cancer provided the best results regarding kidney and spinal cord exposure with adequate clinical target volume coverage. This technique was readily implemented in clinical practice.

  16. On the solution of a vectorial radiative transfer equation in an arbitrary three-dimensional turbid medium with anisotropic scattering

    International Nuclear Information System (INIS)

    Budak, Vladimir P.; Korkin, Sergey V.

    2008-01-01

    The authors developed a numerical method of the boundary-value problem solution in the vectorial radiative transfer theory applicable to the turbid media with an arbitrary three-dimensional geometry. The method is based on the solution representation as the sum of an anisotropic part that contains all the singularities of the exact solution and a smooth regular part. The regular part of the solution could be found numerically by the finite element method that enables to extend the approach to the arbitrary medium geometry. The anisotropic part of the solution is determined analytically by the special form of the small-angle approximation. The method development is performed by the examples of the boundary-value problems for the plane unidirectional and point isotropic sources in a turbid medium slab

  17. Three-dimensional low-energy topological invariants

    International Nuclear Information System (INIS)

    Bakalarska, M.; Broda, B.

    2000-01-01

    A description of the one-loop approximation formula for the partition function of a three-dimensional abelian version of the Donaldson-Witten theory is proposed. The one-loop expression is shown to contain such topological invariants of a three-dimensional manifold M like the Reidemeister-Ray-Singer torsion τ R and Betti numbers. (orig.)

  18. Dose escalation of chart in non-small cell lung cancer: is three-dimensional conformal radiation therapy really necessary?

    International Nuclear Information System (INIS)

    McGibney, Carol; Holmberg, Ola; McClean, Brendan; Williams, Charles; McCrea, Pamela; Sutton, Phil; Armstrong, John

    1999-01-01

    Purpose: To evaluate, pre clinically, the potential for dose escalation of continuous, hyperfractionated, accelerated radiation therapy (CHART) for non small-cell lung cancer (NSCLC), we examined the strategy of omission of elective nodal irradiation with and without the application of three-dimensional conformal radiation technology (3DCRT). Methods and Materials: 2D, conventional therapy plans were designed according to the specifications of CHART for 18 patients with NSCLC (Stages Ib, IIb, IIIa, and IIIb). Further plans were generated with the omission of elective nodal irradiation (ENI) from the treatment portals (2D minus ENI plans [2D-ENI plans]). Both sets were inserted in the patient's planning computed tomographies (CTs). These reconstructed plans were then compared to alternative, three-dimensional treatment plans which had been generated de novo, with the omission of ENI: 3D minus elective nodal irradiation (3D-ENI plans). Dose delivery to the planning target volumes (PTVs) and to the organs at risk were compared between the 3 sets of corresponding plans. The potential for dose escalation of each patient's 2D-ENI and 3D-ENI plan beyond 54 Gy, standard to CHART, was also determined. Results: PTV coverage was suboptimal in the 2D CHART and the 2D-ENI plans. Only in the 3D-ENI plans did 100% of the PTV get ≥95% of the dose prescribed (i.e., 51.5 Gy [51.3-52.2]). Using 3D-ENI plans significantly reduced the dose received by the spinal cord, the mean and median doses to the esophagus and the heart. It did not significantly reduce the lung dose when compared to 2D-ENI plans. Escalation of the dose (minimum ≥1 Gy) with optimal PTV coverage was possible in 55.5% of patients using 3D-ENI, but was possible only in 16.6% when using the 2D-ENI planning strategy. Conclusions: 3DCRT is fundamental to achieving optimal PTV coverage in NSCLC. A policy of omission of elective nodal irradiation alone (and using 2D technology) will not achieve optimal PTV coverage or

  19. FAST: a three-dimensional time-dependent FEL simulation code

    International Nuclear Information System (INIS)

    Saldin, E.L.; Schneidmiller, E.A.; Yurkov, M.V.

    1999-01-01

    In this report we briefly describe the three-dimensional, time-dependent FEL simulation code FAST. The equations of motion of the particles and Maxwell's equations are solved simultaneously taking into account the slippage effect. Radiation fields are calculated using an integral solution of Maxwell's equations. A special technique has been developed for fast calculations of the radiation field, drastically reducing the required CPU time. As a result, the developed code allows one to use a personal computer for time-dependent simulations. The code allows one to simulate the radiation from the electron bunch of any transverse and longitudinal bunch shape; to simulate simultaneously an external seed with superimposed noise in the electron beam; to take into account energy spread in the electron beam and the space charge fields; and to simulate a high-gain, high-efficiency FEL amplifier with a tapered undulator. It is important to note that there are no significant memory limitations in the developed code and an electron bunch of any length can be simulated

  20. [Bone drilling simulation by three-dimensional imaging].

    Science.gov (United States)

    Suto, Y; Furuhata, K; Kojima, T; Kurokawa, T; Kobayashi, M

    1989-06-01

    The three-dimensional display technique has a wide range of medical applications. Pre-operative planning is one typical application: in orthopedic surgery, three-dimensional image processing has been used very successfully. We have employed this technique in pre-operative planning for orthopedic surgery, and have developed a simulation system for bone-drilling. Positive results were obtained by pre-operative rehearsal; when a region of interest is indicated by means of a mouse on the three-dimensional image displayed on the CRT, the corresponding region appears on the slice image which is displayed simultaneously. Consequently, the status of the bone-drilling is constantly monitored. In developing this system, we have placed emphasis on the quality of the reconstructed three-dimensional images, on fast processing, and on the easy operation of the surgical planning simulation.

  1. Three-Dimensional Printing Surgical Applications.

    Science.gov (United States)

    AlAli, Ahmad B; Griffin, Michelle F; Butler, Peter E

    2015-01-01

    Three-dimensional printing, a technology used for decades in the industrial field, gains a lot of attention in the medical field for its potential benefits. With advancement of desktop printers, this technology is accessible and a lot of research is going on in the medical field. To evaluate its application in surgical field, which may include but not limited to surgical planning, surgical education, implants, and prosthesis, which are the focus of this review. Research was conducted by searching PubMed, Web of science, and other reliable sources. We included original articles and excluded articles based on animals, those more than 10 years old, and those not in English. These articles were evaluated, and relevant studies were included in this review. Three-dimensional printing shows a potential benefit in surgical application. Printed implants were used in patient in a few cases and show successful results; however, longer follow-up and more trials are needed. Surgical and medical education is believed to be more efficient with this technology than the current practice. Printed surgical instrument and surgical planning are also believed to improve with three-dimensional printing. Three-dimensional printing can be a very powerful tool in the near future, which can aid the medical field that is facing a lot of challenges and obstacles. However, despite the reported results, further research on larger samples and analytical measurements should be conducted to ensure this technology's impact on the practice.

  2. The Three-dimensional Digital Factory for Shipbuilding Technology Research

    Directory of Open Access Journals (Sweden)

    Xu Wei

    2016-01-01

    Full Text Available The three-dimensional digital factory technology research is the hotspot in shipbuilding recently. The three-dimensional digital factory technology not only focus on design the components of the product, but also discuss on the simulation and analyses of the production process.Based on the three-dimensional model, the basic data layer, application control layer and the presentation layer of hierarchical structure are established in the three-dimensional digital factory of shipbuilding in this paper. And the key technologies of three-dimensional digital factory of shipbuilding are analysed. Finally, a case study is applied and the results show that the three-dimensional digital factory will play an important role in the future.

  3. Resonance fluorescence microscopy via three-dimensional atom localization

    Science.gov (United States)

    Panchadhyayee, Pradipta; Dutta, Bibhas Kumar; Das, Nityananda; Mahapatra, Prasanta Kumar

    2018-02-01

    A scheme is proposed to realize three-dimensional (3D) atom localization in a driven two-level atomic system via resonance fluorescence. The field arrangement for the atom localization involves the application of three mutually orthogonal standing-wave fields and an additional traveling-wave coupling field. We have shown the efficacy of such field arrangement in tuning the spatially modulated resonance in all directions. Under different parametric conditions, the 3D localization patterns originate with various shapes such as sphere, sheets, disk, bowling pin, snake flute, flower vase. High-precision localization is achieved when the radiation field detuning equals twice the combined Rabi frequencies of the standing-wave fields. Application of a traveling-wave field of suitable amplitude at optimum radiation field detuning under symmetric standing-wave configuration leads to 100% detection probability even in sub-wavelength domain. Asymmetric field configuration is also taken into consideration to exhibit atom localization with appreciable precision compared to that of the symmetric case. The momentum distribution of the localized atoms is found to follow the Heisenberg uncertainty principle under the validity of Raman-Nath approximation. The proposed field configuration is suitable for application in the study of atom localization in an optical lattice arrangement.

  4. Three-dimensional assessment of brain tissue morphology

    Science.gov (United States)

    Müller, Bert; Germann, Marco; Jeanmonod, Daniel; Morel, Anne

    2006-08-01

    The microstructure of brain tissues becomes visible using different types of optical microscopy after the tissue sectioning. This preparation procedure introduces stress and strain in the anisotropic and inhomogeneous soft tissue slices, which are several 10 μm thick. Consequently, the three-dimensional dataset, generated out of the two-dimensional images with lateral submicrometer resolution, needs algorithms to correct the deformations, which can be significant for mellow tissue such as brain segments. The spatial resolution perpendicular to the slices is much worse with respect to the lateral sub-micrometer resolution. Therefore, we propose as complementary method the synchrotron-radiation-based micro computed tomography (SRμCT), which avoids any kind of preparation artifacts due to sectioning and histological processing and yields true micrometer resolution in the three orthogonal directions. The visualization of soft matter by the use of SRμCT, however, is often based on elaborate staining protocols, since the tissue exhibits (almost) the same x-ray absorption as the surrounding medium. Therefore, it is unexpected that human tissue from the pons and the medulla oblongata in phosphate buffer show several features such as the blood vessels and the inferior olivary nucleus without staining. The value of these tomograms lies especially in the precise non-rigid registration of the different sets of histological slices. Applications of this method to larger pieces of brain tissue, such as the human thalamus are planned in the context of stereotactic functional neurosurgery.

  5. Towards three-dimensional optical metamaterials

    Science.gov (United States)

    Tanaka, Takuo; Ishikawa, Atsushi

    2017-12-01

    Metamaterials have opened up the possibility of unprecedented and fascinating concepts and applications in optics and photonics. Examples include negative refraction, perfect lenses, cloaking, perfect absorbers, and so on. Since these metamaterials are man-made materials composed of sub-wavelength structures, their development strongly depends on the advancement of micro- and nano-fabrication technologies. In particular, the realization of three-dimensional metamaterials is one of the big challenges in this research field. In this review, we describe recent progress in the fabrication technologies for three-dimensional metamaterials, as well as proposed applications.

  6. Three-dimensional imaging modalities in endodontics

    Science.gov (United States)

    Mao, Teresa

    2014-01-01

    Recent research in endodontics has highlighted the need for three-dimensional imaging in the clinical arena as well as in research. Three-dimensional imaging using computed tomography (CT) has been used in endodontics over the past decade. Three types of CT scans have been studied in endodontics, namely cone-beam CT, spiral CT, and peripheral quantitative CT. Contemporary endodontics places an emphasis on the use of cone-beam CT for an accurate diagnosis of parameters that cannot be visualized on a two-dimensional image. This review discusses the role of CT in endodontics, pertaining to its importance in the diagnosis of root canal anatomy, detection of peri-radicular lesions, diagnosis of trauma and resorption, presurgical assessment, and evaluation of the treatment outcome. PMID:25279337

  7. Three-dimensional imaging modalities in endodontics

    Energy Technology Data Exchange (ETDEWEB)

    Mao, Teresa; Neelakantan, Prasanna [Dept. of Conservative Dentistry and Endodontics, Saveetha Dental College and Hospitals, Saveetha University, Chennai (India)

    2014-09-15

    Recent research in endodontics has highlighted the need for three-dimensional imaging in the clinical arena as well as in research. Three-dimensional imaging using computed tomography (CT) has been used in endodontics over the past decade. Three types of CT scans have been studied in endodontics, namely cone-beam CT, spiral CT, and peripheral quantitative CT. Contemporary endodontics places an emphasis on the use of cone-beam CT for an accurate diagnosis of parameters that cannot be visualized on a two-dimensional image. This review discusses the role of CT in endodontics, pertaining to its importance in the diagnosis of root canal anatomy, detection of peri-radicular lesions, diagnosis of trauma and resorption, presurgical assessment, and evaluation of the treatment outcome.

  8. Three-dimensional imaging modalities in endodontics

    International Nuclear Information System (INIS)

    Mao, Teresa; Neelakantan, Prasanna

    2014-01-01

    Recent research in endodontics has highlighted the need for three-dimensional imaging in the clinical arena as well as in research. Three-dimensional imaging using computed tomography (CT) has been used in endodontics over the past decade. Three types of CT scans have been studied in endodontics, namely cone-beam CT, spiral CT, and peripheral quantitative CT. Contemporary endodontics places an emphasis on the use of cone-beam CT for an accurate diagnosis of parameters that cannot be visualized on a two-dimensional image. This review discusses the role of CT in endodontics, pertaining to its importance in the diagnosis of root canal anatomy, detection of peri-radicular lesions, diagnosis of trauma and resorption, presurgical assessment, and evaluation of the treatment outcome

  9. A three-dimensional field solutions of Halbach

    International Nuclear Information System (INIS)

    Chen Jizhong; Xiao Jijun; Zhang Yiming; Xu Chunyan

    2008-01-01

    A three-dimensional field solutions are presented for Halback cylinder magnet. Based on Ampere equivalent current methods, the permanent magnets are taken as distributing of current density. For getting the three-dimensional field solution of ideal polarized permanent magnets, the solution method entails the use of the vector potential and involves the closed-form integration of the free-space Green's function. The programmed field solution are ideal for performing rapid parametric studies of the dipole Halback cylinder magnets made from rare earth materials. The field solutions are verified by both an analytical two-dimensional algorithm and three-dimensional finite element software. A rapid method is presented for extensive analyzing and optimizing Halbach cylinder magnet. (authors)

  10. Hawking radiation of five-dimensional charged black holes with scalar fields

    Directory of Open Access Journals (Sweden)

    Yan-Gang Miao

    2017-09-01

    Full Text Available We investigate the Hawking radiation cascade from the five-dimensional charged black hole with a scalar field coupled to higher-order Euler densities in a conformally invariant manner. We give the semi-analytic calculation of greybody factors for the Hawking radiation. Our analysis shows that the Hawking radiation cascade from this five-dimensional black hole is extremely sparse. The charge enhances the sparsity of the Hawking radiation, while the conformally coupled scalar field reduces this sparsity.

  11. Transient analysis of cutoff waveguide antenna in three-dimensional space

    International Nuclear Information System (INIS)

    Kashiwa, Tatsuya; Yoshida, Norinobu; Fukai, Ichiro

    1986-01-01

    Recently, the exciting system for electric power heating as seen in nuclear fusion plasma heating and medical purpose has been actively studied and developed. Since such system treats basically a neighborhood field, various problems unlike conventional exciting system for communication arise. In such situation, the structure having the waveguides of simple and robust construction as the main body has been proposed. In this exciting system including the condition of media, the complex distribution of a neighborhood field based on a three-dimensional structure exerts an important effect on the characteristics. Especially in large power excitation, the higher mode of relatively small power distribution cannot be neglected. Besides, also a transient field distribution exerts an important effect on the characteristics, and the time response analysis is required. In this analysis, by the three-dimensional time response analysis method using Bergeron method, the unified analysis of the total system comprising a cutoff waveguide, a coaxial exciting part and a heating region was carried out for determining a radiation neighborhood electromagnetic field by a cutoff waveguide antenna. (Kako, I.)

  12. Three Dimensional Dirac Semimetals

    Science.gov (United States)

    Zaheer, Saad

    2014-03-01

    Dirac points on the Fermi surface of two dimensional graphene are responsible for its unique electronic behavior. One can ask whether any three dimensional materials support similar pseudorelativistic physics in their bulk electronic spectra. This possibility has been investigated theoretically and is now supported by two successful experimental demonstrations reported during the last year. In this talk, I will summarize the various ways in which Dirac semimetals can be realized in three dimensions with primary focus on a specific theory developed on the basis of representations of crystal spacegroups. A three dimensional Dirac (Weyl) semimetal can appear in the presence (absence) of inversion symmetry by tuning parameters to the phase boundary separating a bulk insulating and a topological insulating phase. More generally, we find that specific rules governing crystal symmetry representations of electrons with spin lead to robust Dirac points at high symmetry points in the Brillouin zone. Combining these rules with microscopic considerations identifies six candidate Dirac semimetals. Another method towards engineering Dirac semimetals involves combining crystal symmetry and band inversion. Several candidate materials have been proposed utilizing this mechanism and one of the candidates has been successfully demonstrated as a Dirac semimetal in two independent experiments. Work carried out in collaboration with: Julia A. Steinberg, Steve M. Young, J.C.Y. Teo, C.L. Kane, E.J. Mele and Andrew M. Rappe.

  13. Three-dimensional instability of standing waves

    Science.gov (United States)

    Zhu, Qiang; Liu, Yuming; Yue, Dick K. P.

    2003-12-01

    We investigate the three-dimensional instability of finite-amplitude standing surface waves under the influence of gravity. The analysis employs the transition matrix (TM) approach and uses a new high-order spectral element (HOSE) method for computation of the nonlinear wave dynamics. HOSE is an extension of the original high-order spectral method (HOS) wherein nonlinear wave wave and wave body interactions are retained up to high order in wave steepness. Instead of global basis functions in HOS, however, HOSE employs spectral elements to allow for complex free-surface geometries and surface-piercing bodies. Exponential convergence of HOS with respect to the total number of spectral modes (for a fixed number of elements) and interaction order is retained in HOSE. In this study, we use TM-HOSE to obtain the stability of general three-dimensional perturbations (on a two-dimensional surface) on two classes of standing waves: plane standing waves in a rectangular tank; and radial/azimuthal standing waves in a circular basin. For plane standing waves, we confirm the known result of two-dimensional side-bandlike instability. In addition, we find a novel three-dimensional instability for base flow of any amplitude. The dominant component of the unstable disturbance is an oblique (standing) wave oriented at an arbitrary angle whose frequency is close to the (nonlinear) frequency of the original standing wave. This finding is confirmed by direct long-time simulations using HOSE which show that the nonlinear evolution leads to classical Fermi Pasta Ulam recurrence. For the circular basin, we find that, beyond a threshold wave steepness, a standing wave (of nonlinear frequency Omega) is unstable to three-dimensional perturbations. The unstable perturbation contains two dominant (standing-wave) components, the sum of whose frequencies is close to 2Omega. From the cases we consider, the critical wave steepness is found to generally decrease/increase with increasing radial

  14. On the diversity and statistical properties of protostellar discs

    Science.gov (United States)

    Bate, Matthew R.

    2018-04-01

    We present results from the first population synthesis study of protostellar discs. We analyse the evolution and properties of a large sample of protostellar discs formed in a radiation hydrodynamical simulation of star cluster formation. Due to the chaotic nature of the star formation process, we find an enormous diversity of young protostellar discs, including misaligned discs, and discs whose orientations vary with time. Star-disc interactions truncate discs and produce multiple systems. Discs may be destroyed in dynamical encounters and/or through ram-pressure stripping, but reform by later gas accretion. We quantify the distributions of disc mass and radii for protostellar ages up to ≈105 yr. For low-mass protostars, disc masses tend to increase with both age and protostellar mass. Disc radii range from of order 10 to a few hundred au, grow in size on time-scales ≲ 104 yr, and are smaller around lower mass protostars. The radial surface density profiles of isolated protostellar discs are flatter than the minimum mass solar nebula model, typically scaling as Σ ∝ r-1. Disc to protostar mass ratios rarely exceed two, with a typical range of Md/M* = 0.1-1 to ages ≲ 104 yr and decreasing thereafter. We quantify the relative orientation angles of circumstellar discs and the orbit of bound pairs of protostars, finding a preference for alignment that strengths with decreasing separation. We also investigate how the orientations of the outer parts of discs differ from the protostellar and inner disc spins for isolated protostars and pairs.

  15. Cylindrical Three-Dimensional Porous Anodic Alumina Networks

    Directory of Open Access Journals (Sweden)

    Pedro M. Resende

    2016-11-01

    Full Text Available The synthesis of a conformal three-dimensional nanostructure based on porous anodic alumina with transversal nanopores on wires is herein presented. The resulting three-dimensional network exhibits the same nanostructure as that obtained on planar geometries, but with a macroscopic cylindrical geometry. The morphological analysis of the nanostructure revealed the effects of the initial defects on the aluminum surface and the mechanical strains on the integrity of the three-dimensional network. The results evidence the feasibility of obtaining 3D porous anodic alumina on non-planar aluminum substrates.

  16. Three-dimensional printer-aided casting of soft, custom silicone boluses (SCSBs) for head and neck radiation therapy.

    Science.gov (United States)

    Chiu, Tsuicheng; Tan, Jun; Brenner, Mathew; Gu, Xuejun; Yang, Ming; Westover, Kenneth; Strom, Tobin; Sher, David; Jiang, Steve; Zhao, Bo

    Custom tissue compensators provide dosimetric advantages for treating superficial or complex anatomy, but currently available fabrication technology is expensive or impractical for most clinical operations and yields compensators that are difficult for patients to tolerate. We aimed to develop an inexpensive, clinically feasible workflow for generating patient-specific, soft, custom silicone boluses (SCSBs) for head-and-neck (HN) radiation therapy. We developed a method using 3-dimensional printed parts for generating SCSBs for the treatment of HN cancers. The clinical workflow for generation of SCSBs was characterized inclusive of patient simulation to treatment in terms of resource time and cost. Dosimetric properties such as percentage depth dose and dose profiles were measured for SCSBs using GaF films. Comprehensive measurements were also conducted on an HN phantom. SCSBs were generated and used for electron or photon based radiation treatments of 7 HN patients with lesions at nose, cheek, eye, or ears. In vivo dose measurements with optically simulated luminescence dosimeters were performed. Total design and fabrication time from patient simulation to radiation treatment start required approximately 1 week, with fabrication constituting 1 to 2 working days depending on bolus surface area, volume, and complexity. Computed tomography and dosimetric properties of the soft bolus were similar to water. In vivo dose measurements on 7 treated patients confirmed that the dose deposition conformed to planned doses. Material costs were lower than currently available hard plastic boluses generated with 3-dimensional printing technology. All treated patients tolerated SCSBs for the duration of therapy. Generation and use of SCSBs for clinical use is feasible and effective for the treatment of HN cancers. Copyright © 2017 American Society for Radiation Oncology. Published by Elsevier Inc. All rights reserved.

  17. Three-dimensional analysis of free-electron laser performance using brightness scaled variables

    Directory of Open Access Journals (Sweden)

    M. Gullans

    2008-06-01

    Full Text Available A three-dimensional analysis of radiation generation in a free-electron laser (FEL is performed in the small signal regime. The analysis includes beam conditioning, harmonic generation, flat beams, and a new scaling of the FEL equations using the six-dimensional beam brightness. The six-dimensional beam brightness is an invariant under Liouvillian flow; therefore, any nondissipative manipulation of the phase space, performed, for example, in order to optimize FEL performance, must conserve this brightness. This scaling is more natural than the commonly used scaling with the one-dimensional growth rate. The brightness-scaled equations allow for the succinct characterization of the optimal FEL performance under various additional constraints. The analysis allows for the simple evaluation of gain enhancement schemes based on beam phase space manipulations such as emittance exchange and conditioning. An example comparing the gain in the first and third harmonics of round or flat and conditioned or unconditioned beams is presented.

  18. Multiparallel Three-Dimensional Optical Microscopy

    Science.gov (United States)

    Nguyen, Lam K.; Price, Jeffrey H.; Kellner, Albert L.; Bravo-Zanoquera, Miguel

    2010-01-01

    Multiparallel three-dimensional optical microscopy is a method of forming an approximate three-dimensional image of a microscope sample as a collection of images from different depths through the sample. The imaging apparatus includes a single microscope plus an assembly of beam splitters and mirrors that divide the output of the microscope into multiple channels. An imaging array of photodetectors in each channel is located at a different distance along the optical path from the microscope, corresponding to a focal plane at a different depth within the sample. The optical path leading to each photodetector array also includes lenses to compensate for the variation of magnification with distance so that the images ultimately formed on all the photodetector arrays are of the same magnification. The use of optical components common to multiple channels in a simple geometry makes it possible to obtain high light-transmission efficiency with an optically and mechanically simple assembly. In addition, because images can be read out simultaneously from all the photodetector arrays, the apparatus can support three-dimensional imaging at a high scanning rate.

  19. The life cycles of Be viscous decretion discs: fundamental disc parameters of 54 SMC Be stars

    Science.gov (United States)

    Rímulo, L. R.; Carciofi, A. C.; Vieira, R. G.; Rivinius, Th; Faes, D. M.; Figueiredo, A. L.; Bjorkman, J. E.; Georgy, C.; Ghoreyshi, M. R.; Soszyński, I.

    2018-05-01

    Be stars are main-sequence massive stars with emission features in their spectrum, which originates in circumstellar gaseous discs. Even though the viscous decretion disc model can satisfactorily explain most observations, two important physical ingredients, namely the magnitude of the viscosity (α) and the disc mass injection rate, remain poorly constrained. The light curves of Be stars that undergo events of disc formation and dissipation offer an opportunity to constrain these quantities. A pipeline was developed to model these events that use a grid of synthetic light curves, computed from coupled hydrodynamic and radiative transfer calculations. A sample of 54 Be stars from the OGLE survey of the Small Magellanic Cloud (SMC) was selected for this study. Because of the way our sample was selected (bright stars with clear disc events), it likely represents the densest discs in the SMC. Like their siblings in the Galaxy, the mass of the disc in the SMC increases with the stellar mass. The typical mass and angular momentum loss rates associated with the disc events are of the order of ˜10-10 M⊙ yr-1 and ˜5 × 1036 g cm2 s-2, respectively. The values of α found in this work are typically of a few tenths, consistent with recent results in the literature and with the ones found in dwarf novae, but larger than current theory predicts. Considering the sample as a whole, the viscosity parameter is roughly two times larger at build-up ( = 0.63) than at dissipation ( = 0.26). Further work is necessary to verify whether this trend is real or a result of some of the model assumptions.

  20. Backlund transformations and three-dimensional lattice equations

    NARCIS (Netherlands)

    Nijhoff, F.W.; Capel, H.W.; Wiersma, G.L.; Quispel, G.R.W.

    1984-01-01

    A (nonlocal) linear integral equation is studied, which allows for Bäcklund transformations in the measure. The compatibility of three of these transformations leads to an integrable nonlinear three-dimensional lattice equation. In appropriate continuum limits the two-dimensional Toda-lattice

  1. Arching in three-dimensional clogging

    Science.gov (United States)

    Török, János; Lévay, Sára; Szabó, Balázs; Somfai, Ellák; Wegner, Sandra; Stannarius, Ralf; Börzsönyi, Tamás

    2017-06-01

    Arching in dry granular material is a long established concept, however it remains still an open question how three-dimensional orifices clog. We investigate by means of numerical simulations and experimental data how the outflow creates a blocked configuration of particles. We define the concave surface of the clogged dome by two independent methods (geometric and density based). The average shape of the cupola for spheres is almost a hemisphere but individual samples have large holes in the structure indicating a blocked state composed of two-dimensional force chains rather than three-dimensional objects. The force chain structure justifies this assumption. For long particles the clogged configurations display large variations, and in certain cases the empty region reaches a height of 5 hole diameters. These structures involve vertical walls consisting of horizontally placed stable stacking of particles.

  2. Three-dimensional reconstruction of the biliary tract using spiral computed tomography. Three-dimensional cholangiography

    International Nuclear Information System (INIS)

    Gon, Masanori; Ogura, Norihiro; Uetsuji, Shouji; Ueyama, Yasuo

    1995-01-01

    In this study, 310 patients with benign biliary diseases, 20 with gallbladder cancer, and 8 with biliary tract carcinoma underwent spiral CT (SCT) scanning at cholangiography. Depiction rate of the shape of the conjunction site of the gallbladder and biliary tract was 27.5% by conventional intravenous cholangiography (DIC), 92.5% by ERC, and 90.0% by DIC-SCT. Abnormal cystic duct course was admitted in 14.1%. Multiplanar reconstruction by DIC-SCT enabled identification of the common bile duct and intrahepatic bile duct stone. Three-dimensional reconstruction of DIC-SCT was effective in evaluating obstruction of the anastomosis or passing condition of after hepatico-jejunostomy. Two-dimensional SCT images through PTCD tube enabled degree of hepatic invasion in bile duct cancer, and three-dimensional images were useful in grasping the morphology of the bile duct branches near the obstruction site. DIC-SCT is therefore considered a useful procedure as non-invasive examination of bile duct lesions. (S.Y.)

  3. Three-dimensional microscale modelling of CO2 transport and light propagation in tomato leaves enlightens photosynthesis

    NARCIS (Netherlands)

    Ho, Q.T.; Berghuijs, H.N.C.; Watté, R.; Verboven, P.; Herremans, E.; Yin, X.; Retta, M.A.; Aernouts, B.; Saeys, W.; Helfen, L.; Farquhar, G.D.; Struik, P.C.; Nicolai, B.

    2016-01-01

    We present a combined three-dimensional (3-D) model of light propagation, CO2 diffusion and photosynthesis in tomato (Solanum lycopersicum L.) leaves. The model incorporates a geometrical representation of the actual leaf microstructure that we obtained with synchrotron radiation X-ray laminography,

  4. Induction chemotherapy plus three-dimensional conformal radiation therapy in the definitive treatment of locally advanced non-small-cell lung cancer

    International Nuclear Information System (INIS)

    Sim, Sang; Rosenzweig, Kenneth E.; Schindelheim, Rachel; Ng, Kenneth K.; Leibel, Steven A.

    2001-01-01

    Purpose: To evaluate our institution's experience using chemotherapy in conjunction with three-dimensional conformal radiation therapy (3D-CRT). Methods and Materials: From 1991 to 1998, 152 patients with Stage III non-small-cell lung cancer (NSCLC) were treated with 3D-CRT at Memorial Sloan-Kettering Cancer Center. A total of 137 patients (90%) were surgically staged with either thoracotomy or mediastinoscopy. The remainder were staged radiographically. Seventy patients were treated with radiation therapy alone, and 82 patients received induction chemotherapy before radiation. The majority of chemotherapy-treated patients received a platinum-containing regimen. Radiation was delivered with a 3D conformal technique using CT-based treatment planning. The median dose in the radiation alone group was 70.2 Gy, while in the combined modality group, it was 64.8 Gy. Results: The median follow-up time was 30.5 months among survivors. Stage IIIB disease was present in 36 patients (51%) in the radiation-alone group and 57 patients (70%) in the combined-modality group. Thirty-nine patients had poor prognostic factors (KPS 5%), and they were equally distributed between the two groups. The median survival times for the radiation-alone and the combined-modality groups were 11.7 months and 18.1 months, respectively (p=0.001). The 2-year rates of local control in the radiation-alone and combined-modality groups were 35.4% and 43.1%, respectively (p=0.1). Grade 3 or worse nonhematologic toxicity occurred in 20% of the patients receiving radiation alone and in 16% of those receiving chemotherapy and radiation. Overall, there were only 4 cases of Grade 3 or worse esophagitis. Conclusion: Despite more Stage IIIB patients in the combined-modality group, the addition of chemotherapy to 3D-CRT produced a survival advantage over 3D-CRT alone in Stage III NSCLC without a concomitant increase in toxicity. Chemotherapy thus appears to be beneficial, even in patients who are receiving higher

  5. Three-dimensional appearance of the lips muscles with three-dimensional isotropic MRI: in vivo study

    Energy Technology Data Exchange (ETDEWEB)

    Olszewski, Raphael; Reychler, H. [Universite Catholique de Louvain, Department of Oral and Maxillofacial Surgery, Cliniques Universitaires Saint Luc, Brussels (Belgium); Liu, Y.; Xu, T.M. [Peking University School and Hospital of Stomatology, Department of Orthodontics, Beijing (China); Duprez, T. [Universite Catholique de Louvain, Department of Radiology, Cliniques Universitaires Saint Luc, Brussels (Belgium)

    2009-06-15

    Our knowledge of facial muscles is based primarily on atlases and cadaveric studies. This study describes a non-invasive in vivo method (3D MRI) for segmenting and reconstructing facial muscles in a three-dimensional fashion. Three-dimensional (3D), T1-weighted, 3 Tesla, isotropic MRI was applied to a subject. One observer performed semi-automatic segmentation using the Editor module from the 3D Slicer software (Harvard Medical School, Boston, MA, USA), version 3.2. We were able to successfully outline and three-dimensionally reconstruct the following facial muscles: pars labialis orbicularis oris, m. levatro labii superioris alaeque nasi, m. levator labii superioris, m. zygomaticus major and minor, m. depressor anguli oris, m. depressor labii inferioris, m. mentalis, m. buccinator, and m. orbicularis oculi. 3D reconstruction of the lip muscles should be taken into consideration in order to improve the accuracy and individualization of existing 3D facial soft tissue models. More studies are needed to further develop efficient methods for segmentation in this field. (orig.)

  6. Three-dimensional appearance of the lips muscles with three-dimensional isotropic MRI: in vivo study.

    Science.gov (United States)

    Olszewski, Raphael; Liu, Y; Duprez, T; Xu, T M; Reychler, H

    2009-06-01

    Our knowledge of facial muscles is based primarily on atlases and cadaveric studies. This study describes a non-invasive in vivo method (3D MRI) for segmenting and reconstructing facial muscles in a three-dimensional fashion. Three-dimensional (3D), T1-weighted, 3 Tesla, isotropic MRI was applied to a subject. One observer performed semi-automatic segmentation using the Editor module from the 3D Slicer software (Harvard Medical School, Boston, MA, USA), version 3.2. We were able to successfully outline and three-dimensionally reconstruct the following facial muscles: pars labialis orbicularis oris, m. levatro labii superioris alaeque nasi, m. levator labii superioris, m. zygomaticus major and minor, m. depressor anguli oris, m. depressor labii inferioris, m. mentalis, m. buccinator, and m. orbicularis oculi. 3D reconstruction of the lip muscles should be taken into consideration in order to improve the accuracy and individualization of existing 3D facial soft tissue models. More studies are needed to further develop efficient methods for segmentation in this field.

  7. Three-dimensional structure of brain tissue at submicrometer resolution

    Energy Technology Data Exchange (ETDEWEB)

    Saiga, Rino; Mizutani, Ryuta, E-mail: ryuta@tokai-u.jp [Department of Applied Biochemistry, Tokai University, Hiratsuka, Kanagawa 259-1292 (Japan); Inomoto, Chie; Takekoshi, Susumu; Nakamura, Naoya; Tsuboi, Akio; Osawa, Motoki [Tokai University School of Medicine, Isehara, Kanagawa 259-1193 (Japan); Arai, Makoto; Oshima, Kenichi; Itokawa, Masanari [Tokyo Metropolitan Institute of Medical Science, Setagaya, Tokyo 156-8506 (Japan); Uesugi, Kentaro; Takeuchi, Akihisa; Terada, Yasuko; Suzuki, Yoshio [Japan Synchrotron Radiation Research Institute (JASRI/SPring-8), Sayo, Hyogo 679-5198 (Japan)

    2016-01-28

    Biological objects are composed of submicrometer structures such as cells and organelles that are essential for their functions. Here, we report on three-dimensional X-ray visualization of cells and organelles at resolutions up to 100 nm by imaging microtomography (micro-CT) equipped with Fresnel zone plate optics. Human cerebral tissue, fruit fly cephalic ganglia, and Escherichia coli bacteria labeled with high atomic-number elements were embedded in epoxy resin and subjected to X-ray microtomography at the BL37XU and BL47XU beamlines of the SPring-8 synchrotron radiation facility. The obtained results indicated that soft tissue structures can be visualized with the imaging microtomography.

  8. Chasing discs around O-type (proto)stars: Evidence from ALMA observations

    NARCIS (Netherlands)

    Cesaroni, R.; Sánchez-Monge, Á.; Beltrán, M. T.; Johnston, K. G.; Maud, L. T.; Moscadelli, L.; Mottram, J. C.; Ahmadi, A.; Allen, V.; Beuther, H.; Csengeri, T.; Etoka, S.; Fuller, G. A.; Galli, D.; Galván-Madrid, R.; Goddi, C.; Henning, T.; Hoare, M. G.; Klaassen, P. D.; Kuiper, R.; Kumar, M. S. N.; Lumsden, S.; Peters, T.; Rivilla, V. M.; Schilke, P.; Testi, L.; van der Tak, F.; Vig, S.; Walmsley, C. M.; Zinnecker, H.

    2017-01-01

    Context. Circumstellar discs around massive stars could mediate the accretion onto the star from the infalling envelope, and could minimize the effects of radiation pressure. Despite such a crucial role, only a few convincing candidates have been provided for discs around deeply embedded O-type

  9. Three-Dimensional Messages for Interstellar Communication

    Science.gov (United States)

    Vakoch, Douglas A.

    One of the challenges facing independently evolved civilizations separated by interstellar distances is to communicate information unique to one civilization. One commonly proposed solution is to begin with two-dimensional pictorial representations of mathematical concepts and physical objects, in the hope that this will provide a foundation for overcoming linguistic barriers. However, significant aspects of such representations are highly conventional, and may not be readily intelligible to a civilization with different conventions. The process of teaching conventions of representation may be facilitated by the use of three-dimensional representations redundantly encoded in multiple formats (e.g., as both vectors and as rasters). After having illustrated specific conventions for representing mathematical objects in a three-dimensional space, this method can be used to describe a physical environment shared by transmitter and receiver: a three-dimensional space defined by the transmitter--receiver axis, and containing stars within that space. This method can be extended to show three-dimensional representations varying over time. Having clarified conventions for representing objects potentially familiar to both sender and receiver, novel objects can subsequently be depicted. This is illustrated through sequences showing interactions between human beings, which provide information about human behavior and personality. Extensions of this method may allow the communication of such culture-specific features as aesthetic judgments and religious beliefs. Limitations of this approach will be noted, with specific reference to ETI who are not primarily visual.

  10. Implementation and modification of a three-dimensional radiation stress formulation for surf zone and rip-current applications

    Science.gov (United States)

    Kumar, N.; Voulgaris, G.; Warner, John C.

    2011-01-01

    Regional Ocean Modeling System (ROMS v 3.0), a three-dimensional numerical ocean model, was previously enhanced for shallow water applications by including wave-induced radiation stress forcing provided through coupling to wave propagation models (SWAN, REF/DIF). This enhancement made it suitable for surf zone applications as demonstrated using examples of obliquely incident waves on a planar beach and rip current formation in longshore bar trough morphology (Haas and Warner, 2009). In this contribution, we present an update to the coupled model which implements a wave roller model and also a modified method of the radiation stress term based on Mellor (2008, 2011a,b,in press) that includes a vertical distribution which better simulates non-conservative (i.e., wave breaking) processes and appears to be more appropriate for sigma coordinates in very shallow waters where wave breaking conditions dominate. The improvements of the modified model are shown through simulations of several cases that include: (a) obliquely incident spectral waves on a planar beach; (b) obliquely incident spectral waves on a natural barred beach (DUCK'94 experiment); (c) alongshore variable offshore wave forcing on a planar beach; (d) alongshore varying bathymetry with constant offshore wave forcing; and (e) nearshore barred morphology with rip-channels. Quantitative and qualitative comparisons to previous analytical, numerical, laboratory studies and field measurements show that the modified model replicates surf zone recirculation patterns (onshore drift at the surface and undertow at the bottom) more accurately than previous formulations based on radiation stress (Haas and Warner, 2009). The results of the model and test cases are further explored for identifying the forces operating in rip current development and the potential implication for sediment transport and rip channel development. Also, model analysis showed that rip current strength is higher when waves approach at angles of 5

  11. Simulating three-dimensional nonthermal high-energy photon emission in colliding-wind binaries

    Energy Technology Data Exchange (ETDEWEB)

    Reitberger, K.; Kissmann, R.; Reimer, A.; Reimer, O., E-mail: klaus.reitberger@uibk.ac.at [Institut für Astro- und Teilchenphysik and Institut für Theoretische Physik, Leopold-Franzens-Universität Innsbruck, A-6020 Innsbruck (Austria)

    2014-07-01

    Massive stars in binary systems have long been regarded as potential sources of high-energy γ rays. The emission is principally thought to arise in the region where the stellar winds collide and accelerate relativistic particles which subsequently emit γ rays. On the basis of a three-dimensional distribution function of high-energy particles in the wind collision region—as obtained by a numerical hydrodynamics and particle transport model—we present the computation of the three-dimensional nonthermal photon emission for a given line of sight. Anisotropic inverse Compton emission is modeled using the target radiation field of both stars. Photons from relativistic bremsstrahlung and neutral pion decay are computed on the basis of local wind plasma densities. We also consider photon-photon opacity effects due to the dense radiation fields of the stars. Results are shown for different stellar separations of a given binary system comprising of a B star and a Wolf-Rayet star. The influence of orbital orientation with respect to the line of sight is also studied by using different orbital viewing angles. For the chosen electron-proton injection ratio of 10{sup –2}, we present the ensuing photon emission in terms of two-dimensional projections maps, spectral energy distributions, and integrated photon flux values in various energy bands. Here, we find a transition from hadron-dominated to lepton-dominated high-energy emission with increasing stellar separations. In addition, we confirm findings from previous analytic modeling that the spectral energy distribution varies significantly with orbital orientation.

  12. Initial three-dimensional neutronics calculations for the EU water cooled lithium-lead test blanket module for ITER-FEAT

    International Nuclear Information System (INIS)

    Jordanova, J.; Poitevin, Y.; Li Puma, A.; Kirov, N.

    2003-01-01

    The paper summarizes the main results of the initial three-dimensional radiation transport analysis of the EU water-cooled lithium-lead test blanket module performed using the Monte Carlo code MCNP. Estimates of tritium production rate, nuclear energy deposition and cumulative fluence effects such as radiation damage through atomic displacement and production of He and H are presented. (author)

  13. Three-dimensional topological insulators and bosonization

    Energy Technology Data Exchange (ETDEWEB)

    Cappelli, Andrea [INFN, Sezione di Firenze,Via G. Sansone 1, 50019 Sesto Fiorentino - Firenze (Italy); Randellini, Enrico [INFN, Sezione di Firenze,Via G. Sansone 1, 50019 Sesto Fiorentino - Firenze (Italy); Dipartimento di Fisica e Astronomia, Università di Firenze,Via G. Sansone 1, 50019 Sesto Fiorentino - Firenze (Italy); Sisti, Jacopo [Scuola Internazionale Superiore di Studi Avanzati (SISSA),Via Bonomea 265, 34136 Trieste (Italy)

    2017-05-25

    Massless excitations at the surface of three-dimensional time-reversal invariant topological insulators possess both fermionic and bosonic descriptions, originating from band theory and hydrodynamic BF theory, respectively. We analyze the corresponding field theories of the Dirac fermion and compactified boson and compute their partition functions on the three-dimensional torus geometry. We then find some non-dynamic exact properties of bosonization in (2+1) dimensions, regarding fermion parity and spin sectors. Using these results, we extend the Fu-Kane-Mele stability argument to fractional topological insulators in three dimensions.

  14. High-resolution three-dimensional mapping of semiconductor dopant potentials

    DEFF Research Database (Denmark)

    Twitchett, AC; Yates, TJV; Newcomb, SB

    2007-01-01

    Semiconductor device structures are becoming increasingly three-dimensional at the nanometer scale. A key issue that must be addressed to enable future device development is the three-dimensional mapping of dopant distributions, ideally under "working conditions". Here we demonstrate how a combin......Semiconductor device structures are becoming increasingly three-dimensional at the nanometer scale. A key issue that must be addressed to enable future device development is the three-dimensional mapping of dopant distributions, ideally under "working conditions". Here we demonstrate how...... a combination of electron holography and electron tomography can be used to determine quantitatively the three-dimensional electrostatic potential in an electrically biased semiconductor device with nanometer spatial resolution....

  15. Equilibrium: three-dimensional configurations

    International Nuclear Information System (INIS)

    Anon.

    1987-01-01

    This chapter considers toroidal MHD configurations that are inherently three-dimensional. The motivation for investigation such complicated equilibria is that they possess the potential for providing toroidal confinement without the need of a net toroidal current. This leads to a number of advantages with respect to fusion power generation. First, the attractive feature of steady-state operation becomes more feasible since such configurations no longer require a toroidal current transformer. Second, with zero net current, one potentially dangerous class of MHD instabilities, the current-driven kink modes, is eliminated. Finally, three-dimensional configurations possess nondegenerate flux surfaces even in the absence of plasma pressure and plasma current. Although there is an enormous range of possible three-dimensional equilibria, the configurations of interest are accurately described as axisymmetric tori with superimposed helical fields; furthermore, they possess no net toroidal current. Instead, two different and less obvious restoring forces are developed: the helical sideband force and the toroidal dipole current force. Each is discussed in detail in Chapter 7. A detailed discussion of the parallel current constraint, including its physical significance, is given in section 7.2. A general analysis of helical sideband equilibria, along with a detailed description of the Elmo bumpy torus, is presented in sections 7.3 and 7.4. A general description of toroidal dipole-current equilibria, including a detailed discussion of stellarators, heliotrons, and torsatrons, is given in sections 7.5 and 7.6

  16. A three-dimensional viscous topography mesoscale model

    Energy Technology Data Exchange (ETDEWEB)

    Eichhorn, J; Flender, M; Kandlbinder, T; Panhans, W G; Trautmann, T; Zdunkowski, W G [Mainz Univ. (Germany). Inst. fuer Physik der Atmosphaere; Cui, K; Ries, R; Siebert, J; Wedi, N

    1997-11-01

    This study describes the theoretical foundation and applications of a newly designed mesoscale model named CLIMM (climate model Mainz). In contrast to terrain following coordinates, a cartesian grid is used to keep the finite difference equations as simple as possible. The method of viscous topography is applied to the flow part of the model. Since the topography intersects the cartesian grid cells, the new concept of boundary weight factors is introduced for the solution of Poisson`s equation. A three-dimensional radiosity model was implemented to handle radiative transfer at the ground. The model is applied to study thermally induced circulations and gravity waves at an idealized mountain. Furthermore, CLIMM was used to simulate typical wind and temperature distributions for the city of Mainz and its rural surroundings. It was found that the model in all cases produced realistic results. (orig.) 38 refs.

  17. Volume scanning three-dimensional display with an inclined two-dimensional display and a mirror scanner

    Science.gov (United States)

    Miyazaki, Daisuke; Kawanishi, Tsuyoshi; Nishimura, Yasuhiro; Matsushita, Kenji

    2001-11-01

    A new three-dimensional display system based on a volume-scanning method is demonstrated. To form a three-dimensional real image, an inclined two-dimensional image is rapidly moved with a mirror scanner while the cross-section patterns of a three-dimensional object are displayed sequentially. A vector-scan CRT display unit is used to obtain a high-resolution image. An optical scanning system is constructed with concave mirrors and a galvanometer mirror. It is confirmed that three-dimensional images, formed by the experimental system, satisfy all the criteria for human stereoscopic vision.

  18. Three-Dimensional Reconstruction and Solar Energy Potential Estimation of Buildings

    Science.gov (United States)

    Chen, Y.; Li, M.; Cheng, L.; Xu, H.; Li, S.; Liu, X.

    2017-12-01

    In the context of the construction of low-carbon cities, green cities and eco-cities, the ability of the airborne and mobile LiDAR should be explored in urban renewable energy research. As the main landscape in urban environment, buildings have large regular envelopes could receive a huge amount of solar radiation. In this study, a relatively complete calculation scheme about building roof and façade solar utilization potential is proposed, using building three-dimensional geometric feature information. For measuring the city-level building solar irradiance, the precise three-dimensional building roof and façade models should be first reconstructed from the airborne and mobile LiDAR, respectively. In order to obtaining the precise geometric structure of building facades from the mobile LiDAR data, a new method for structure detection and the three-dimensional reconstruction of building façades from mobile LiDAR data is proposed. The method consists of three steps: the preprocessing of façade points, the detection of façade structure, the restoration and reconstruction of building façade. As a result, the reconstruction method can effectively deal with missing areas caused by occlusion, viewpoint limitation, and uneven point density, as well as realizing the highly complete 3D reconstruction of a building façade. Furthermore, the window areas can be excluded for more accurate estimation of solar utilization potential. After then, the solar energy utilization potential of global building roofs and facades is estimate by using the solar irradiance model, which combine the analysis of the building shade and sky diffuse, based on the analysis of the geometrical structure of buildings.

  19. Three-dimensional bio-printing.

    Science.gov (United States)

    Gu, Qi; Hao, Jie; Lu, YangJie; Wang, Liu; Wallace, Gordon G; Zhou, Qi

    2015-05-01

    Three-dimensional (3D) printing technology has been widely used in various manufacturing operations including automotive, defence and space industries. 3D printing has the advantages of personalization, flexibility and high resolution, and is therefore becoming increasingly visible in the high-tech fields. Three-dimensional bio-printing technology also holds promise for future use in medical applications. At present 3D bio-printing is mainly used for simulating and reconstructing some hard tissues or for preparing drug-delivery systems in the medical area. The fabrication of 3D structures with living cells and bioactive moieties spatially distributed throughout will be realisable. Fabrication of complex tissues and organs is still at the exploratory stage. This review summarize the development of 3D bio-printing and its potential in medical applications, as well as discussing the current challenges faced by 3D bio-printing.

  20. Acid-base properties of complexes with three-dimensional polyligands. Complexes with three-dimensional polyphosphoric acids

    International Nuclear Information System (INIS)

    Kopylova, V.D.; Bojko, Eh.T.; Saldadze, K.M.

    1985-01-01

    By the method of potentiometric titration acid-base properties of uranyl (2) complexes with three-dimensional polyphosphoric acids, KRF-8p, KF-1, KF-7 prepared by phosphorylation of copolymer of styrene and divinylbenzene or saponification of the copolymers of di-2,2'-chloroethyl ester of vinylphosphonic acid with divinyl benzene are studied. It is shown that in case of formation in the phase of three-dimensional polyphosphoric acids of UO 2 2+ complexes with the growth of bond covalence of metal ion-phosphonic group the acidjty of the second hydroxyl of the phosphonic group increases

  1. Three dimensional periodic foundations for base seismic isolation

    International Nuclear Information System (INIS)

    Yan, Y; Mo, Y L; Cheng, Z; Shi, Z; Menq, F; Tang, Y

    2015-01-01

    Based on the concept of phononic crystals, periodic foundations made of periodic materials are investigated in this paper. The periodic foundations can provide low frequency band gaps, which cover the main frequency ranges of seismic waves. Therefore, the periodic foundations are able to protect the upper structures during earthquake events. In this paper, the basic theory of three dimensional periodic foundations is studied and the finite element method was used to conduct the sensitivity study. A simplified three-dimensional periodic foundation with a superstructure was tested in the field and the feasibility of three dimensional periodic foundations was proved. The test results showed that the response of the upper structure with the three dimensional periodic foundation was reduced under excitation waves with the main frequency falling in the attenuation zones. The finite element analysis results are consistent with the experimental data, indicating that three dimensional periodic foundations are a feasible way of reducing seismic vibrations. (paper)

  2. Disc defect classification for optical disc drives

    NARCIS (Netherlands)

    Helvoirt, van J.; Leenknegt, G.A.L.; Steinbuch, M.; Goossens, H.J.

    2005-01-01

    Optical disc drives are subject to various disturbances and faults. A special type of fault is the so-called disc defect. In this paper we present an approach for disc defect classification. It is based on hierarchical clustering of measured signals that are affected by disc defects. The

  3. Simulation on three dimensional bubble formation using MARS

    International Nuclear Information System (INIS)

    Kunugi, Tomoaki

    1997-01-01

    This paper describes a numerical simulation on three-dimensional bubble formation by means of the MARS (Multi-interfaces Advection and Reconstruction Solver) developed by the author. The comparison between two-dimensional and three-dimensional simulation on an agglomeration of two bubbles is discussed. Moreover, some simulation results regarding a phase change phenomena such as a boiling and condensation in a two dimensional enclosure with heated and cooled walls are presented. (author)

  4. Three-dimensional tori and Arnold tongues

    Energy Technology Data Exchange (ETDEWEB)

    Sekikawa, Munehisa, E-mail: sekikawa@cc.utsunomiya-u.ac.jp [Department of Mechanical and Intelligent Engineering, Utsunomiya University, Utsunomiya-shi 321-8585 (Japan); Inaba, Naohiko [Organization for the Strategic Coordination of Research and Intellectual Property, Meiji University, Kawasaki-shi 214-8571 (Japan); Kamiyama, Kyohei [Department of Electronics and Bioinformatics, Meiji University, Kawasaki-shi 214-8571 (Japan); Aihara, Kazuyuki [Institute of Industrial Science, the University of Tokyo, Meguro-ku 153-8505 (Japan)

    2014-03-15

    This study analyzes an Arnold resonance web, which includes complicated quasi-periodic bifurcations, by conducting a Lyapunov analysis for a coupled delayed logistic map. The map can exhibit a two-dimensional invariant torus (IT), which corresponds to a three-dimensional torus in vector fields. Numerous one-dimensional invariant closed curves (ICCs), which correspond to two-dimensional tori in vector fields, exist in a very complicated but reasonable manner inside an IT-generating region. Periodic solutions emerge at the intersections of two different thin ICC-generating regions, which we call ICC-Arnold tongues, because all three independent-frequency components of the IT become rational at the intersections. Additionally, we observe a significant bifurcation structure where conventional Arnold tongues transit to ICC-Arnold tongues through a Neimark-Sacker bifurcation in the neighborhood of a quasi-periodic Hopf bifurcation (or a quasi-periodic Neimark-Sacker bifurcation) boundary.

  5. Three-Dimensional Dosimetric Validation of a Magnetic Resonance Guided Intensity Modulated Radiation Therapy System

    Energy Technology Data Exchange (ETDEWEB)

    Rankine, Leith J., E-mail: Leith_Rankine@med.unc.edu [Department of Radiation Oncology, Washington University School of Medicine, St Louis, Missouri (United States); Department of Radiation Oncology, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina (United States); Mein, Stewart [Medical Physics Graduate Program, Duke University, Durham, North Carolina (United States); Cai, Bin; Curcuru, Austen [Department of Radiation Oncology, Washington University School of Medicine, St Louis, Missouri (United States); Juang, Titania; Miles, Devin [Medical Physics Graduate Program, Duke University, Durham, North Carolina (United States); Mutic, Sasa; Wang, Yuhe [Department of Radiation Oncology, Washington University School of Medicine, St Louis, Missouri (United States); Oldham, Mark [Medical Physics Graduate Program, Duke University, Durham, North Carolina (United States); Department of Radiation Oncology, Duke University Medical Center, Durham, North Carolina (United States); Li, H. Harold, E-mail: hli@radonc.wustl.edu [Department of Radiation Oncology, Washington University School of Medicine, St Louis, Missouri (United States)

    2017-04-01

    Purpose: To validate the dosimetric accuracy of a commercially available magnetic resonance guided intensity modulated radiation therapy (MRgIMRT) system using a hybrid approach: 3-dimensional (3D) measurements and Monte Carlo calculations. Methods and Materials: We used PRESAGE radiochromic plastic dosimeters with remote optical computed tomography readout to perform 3D high-resolution measurements, following a novel remote dosimetry protocol. We followed the intensity modulated radiation therapy commissioning recommendations of American Association of Physicists in Medicine Task Group 119, adapted to incorporate 3D data. Preliminary tests (“AP” and “3D-Bands”) were delivered to 9.5-cm usable diameter cylindrical PRESAGE dosimeters to validate the treatment planning system (TPS) for nonmodulated deliveries; assess the sensitivity, uniformity, and rotational symmetry of the PRESAGE dosimeters; and test the robustness of the remote dosimetry protocol. Following this, 4 clinical MRgIMRT plans (“MultiTarget,” “Prostate,” “Head/Neck,” and “C-Shape”) were measured using 13-cm usable diameter PRESAGE dosimeters. For all plans, 3D-γ (3% or 3 mm global, 10% threshold) passing rates were calculated and 3D-γ maps were examined. Point doses were measured with an IBA-CC01 ionization chamber for validation of absolute dose. Finally, by use of an in-house-developed, GPU-accelerated Monte Carlo algorithm (gPENELOPE), we independently calculated dose for all 6 Task Group 119 plans and compared against the TPS. Results: For PRESAGE measurements, 3D-γ analysis yielded passing rates of 98.7%, 99.2%, 98.5%, 98.0%, 99.2%, and 90.7% for AP, 3D-Bands, MultiTarget, Prostate, Head/Neck, and C-Shape, respectively. Ion chamber measurements were within an average of 0.5% (±1.1%) from the TPS dose. Monte Carlo calculations demonstrated good agreement with the TPS, with a mean 3D-γ passing rate of 98.5% ± 1.9% using a stricter 2%/2-mm criterion. Conclusions: We

  6. Three-Dimensional Dosimetric Validation of a Magnetic Resonance Guided Intensity Modulated Radiation Therapy System

    International Nuclear Information System (INIS)

    Rankine, Leith J.; Mein, Stewart; Cai, Bin; Curcuru, Austen; Juang, Titania; Miles, Devin; Mutic, Sasa; Wang, Yuhe; Oldham, Mark; Li, H. Harold

    2017-01-01

    Purpose: To validate the dosimetric accuracy of a commercially available magnetic resonance guided intensity modulated radiation therapy (MRgIMRT) system using a hybrid approach: 3-dimensional (3D) measurements and Monte Carlo calculations. Methods and Materials: We used PRESAGE radiochromic plastic dosimeters with remote optical computed tomography readout to perform 3D high-resolution measurements, following a novel remote dosimetry protocol. We followed the intensity modulated radiation therapy commissioning recommendations of American Association of Physicists in Medicine Task Group 119, adapted to incorporate 3D data. Preliminary tests (“AP” and “3D-Bands”) were delivered to 9.5-cm usable diameter cylindrical PRESAGE dosimeters to validate the treatment planning system (TPS) for nonmodulated deliveries; assess the sensitivity, uniformity, and rotational symmetry of the PRESAGE dosimeters; and test the robustness of the remote dosimetry protocol. Following this, 4 clinical MRgIMRT plans (“MultiTarget,” “Prostate,” “Head/Neck,” and “C-Shape”) were measured using 13-cm usable diameter PRESAGE dosimeters. For all plans, 3D-γ (3% or 3 mm global, 10% threshold) passing rates were calculated and 3D-γ maps were examined. Point doses were measured with an IBA-CC01 ionization chamber for validation of absolute dose. Finally, by use of an in-house-developed, GPU-accelerated Monte Carlo algorithm (gPENELOPE), we independently calculated dose for all 6 Task Group 119 plans and compared against the TPS. Results: For PRESAGE measurements, 3D-γ analysis yielded passing rates of 98.7%, 99.2%, 98.5%, 98.0%, 99.2%, and 90.7% for AP, 3D-Bands, MultiTarget, Prostate, Head/Neck, and C-Shape, respectively. Ion chamber measurements were within an average of 0.5% (±1.1%) from the TPS dose. Monte Carlo calculations demonstrated good agreement with the TPS, with a mean 3D-γ passing rate of 98.5% ± 1.9% using a stricter 2%/2-mm criterion. Conclusions: We

  7. Multi-dimensional fiber-optic radiation sensor for ocular proton therapy dosimetry

    International Nuclear Information System (INIS)

    Jang, K.W.; Yoo, W.J.; Moon, J.; Han, K.T.; Park, B.G.; Shin, D.; Park, S-Y.; Lee, B.

    2012-01-01

    In this study, we fabricated a multi-dimensional fiber-optic radiation sensor, which consists of organic scintillators, plastic optical fibers and a water phantom with a polymethyl methacrylate structure for the ocular proton therapy dosimetry. For the purpose of sensor characterization, we measured the spread out Bragg-peak of 120 MeV proton beam using a one-dimensional sensor array, which has 30 fiber-optic radiation sensors with a 1.5 mm interval. A uniform region of spread out Bragg-peak using the one-dimensional fiber-optic radiation sensor was obtained from 20 to 25 mm depth of a phantom. In addition, the Bragg-peak of 109 MeV proton beam was measured at the depth of 11.5 mm of a phantom using a two-dimensional sensor array, which has 10×3 sensor array with a 0.5 mm interval.

  8. Spiral density waves and vertical circulation in protoplanetary discs

    Science.gov (United States)

    Riols, A.; Latter, H.

    2018-06-01

    Spiral density waves dominate several facets of accretion disc dynamics - planet-disc interactions and gravitational instability (GI) most prominently. Though they have been examined thoroughly in two-dimensional simulations, their vertical structures in the non-linear regime are somewhat unexplored. This neglect is unwarranted given that any strong vertical motions associated with these waves could profoundly impact dust dynamics, dust sedimentation, planet formation, and the emissivity of the disc surface. In this paper, we combine linear calculations and shearing box simulations in order to investigate the vertical structure of spiral waves for various polytropic stratifications and wave amplitudes. For sub-adiabatic profiles, we find that spiral waves develop a pair of counter-rotating poloidal rolls. Particularly strong in the non-linear regime, these vortical structures issue from the baroclinicity supported by the background vertical entropy gradient. They are also intimately connected to the disc's g modes which appear to interact non-linearly with the density waves. Furthermore, we demonstrate that the poloidal rolls are ubiquitous in gravitoturbulence, emerging in the vicinity of GI spiral wakes, and potentially transporting grains off the disc mid-plane. Other than hindering sedimentation and planet formation, this phenomena may bear on observations of the disc's scattered infrared luminosity. The vortical features could also impact on the turbulent dynamo operating in young protoplanetary discs subject to GI, or possibly even galactic discs.

  9. A decision model to estimate the cost-effectiveness of intensity modulated radiation therapy (IMRT) compared to three dimensional conformal radiation therapy (3DCRT) in patients receiving radiotherapy to the prostate bed

    International Nuclear Information System (INIS)

    Carter, Hannah E.; Martin, Andrew; Schofield, Deborah; Duchesne, Gillian; Haworth, Annette; Hornby, Colin; Sidhom, Mark; Jackson, Michael

    2014-01-01

    Background: Intensity modulated radiation therapy (IMRT) is a radiation therapy technology that facilitates the delivery of an improved dose distribution with less dose to surrounding critical structures. This study estimates the longer term effectiveness and cost-effectiveness of IMRT in patients post radical prostatectomy. Methods: A Markov decision model was developed to calculate the incremental quality adjusted life years (QALYs) and costs of IMRT compared with three dimensional conformal radiation therapy (3DCRT). Costs were estimated from the perspective of the Australian health care system. Results: IMRT was both more effective and less costly than 3DCRT over 20 years, with an additional 20 QALYs gained and over $1.1 million saved per 1000 patients treated. This result was robust to plausible levels of uncertainty. Conclusions: IMRT was estimated to have a modest long term advantage over 3DCRT in terms of both improved effectiveness and reduced cost. This result was reliant on clinical judgement and interpretation of the existing literature, but provides quantitative guidance on the cost effectiveness of IMRT whilst long term trial evidence is awaited

  10. A new spherical harmonics scheme for multi-dimensional radiation transport I. Static matter configurations

    Energy Technology Data Exchange (ETDEWEB)

    Radice, David, E-mail: david.radice@aei.mpg.de [Max Planck Institute für Gravitationsphysik, Albert Einstein Institute, Potsdam (Germany); Abdikamalov, Ernazar [TAPIR, California Institute of Technology, Pasadena, CA (United States); Rezzolla, Luciano [Max Planck Institute für Gravitationsphysik, Albert Einstein Institute, Potsdam (Germany); Department of Physics and Astronomy, Louisiana State University, Baton Rouge, LA (United States); Ott, Christian D. [TAPIR, California Institute of Technology, Pasadena, CA (United States)

    2013-06-01

    Recent work by McClarren and Hauck (2010) [31] suggests that the filtered spherical harmonics method represents an efficient, robust, and accurate method for radiation transport, at least in the two-dimensional (2D) case. We extend their work to the three-dimensional (3D) case and find that all of the advantages of the filtering approach identified in 2D are present also in the 3D case. We reformulate the filter operation in a way that is independent of the timestep and of the spatial discretization. We also explore different second- and fourth-order filters and find that the second-order ones yield significantly better results. Overall, our findings suggest that the filtered spherical harmonics approach represents a very promising method for 3D radiation transport calculations.

  11. A new spherical harmonics scheme for multi-dimensional radiation transport I. Static matter configurations

    International Nuclear Information System (INIS)

    Radice, David; Abdikamalov, Ernazar; Rezzolla, Luciano; Ott, Christian D.

    2013-01-01

    Recent work by McClarren and Hauck (2010) [31] suggests that the filtered spherical harmonics method represents an efficient, robust, and accurate method for radiation transport, at least in the two-dimensional (2D) case. We extend their work to the three-dimensional (3D) case and find that all of the advantages of the filtering approach identified in 2D are present also in the 3D case. We reformulate the filter operation in a way that is independent of the timestep and of the spatial discretization. We also explore different second- and fourth-order filters and find that the second-order ones yield significantly better results. Overall, our findings suggest that the filtered spherical harmonics approach represents a very promising method for 3D radiation transport calculations

  12. Influence of convective cooling on a disc brake temperature distribution during repetitive braking

    International Nuclear Information System (INIS)

    Adamowicz, Adam; Grzes, Piotr

    2011-01-01

    The purpose of this study is to evaluate an impact of convective mode of heat transfer on the thermal behaviour of a disc brake system during repetitive braking process with the constant velocity using fully three-dimensional finite element model. The transient thermal analysis to determine the temperature distributions on the contact surface of a disc brake is performed. The issue of non-uniform frictional heating effects of mutual slipping of a disc over fixed pads is tested using FE models with the several possible to occur in automotive application heat transfer coefficients. To have a possibility of comparison of the temperature distributions of a disc during cyclic brake application, the energy transformed during time of every analyzed case of braking process and the subsequent release periods was equal. The time-stepping procedure is employed to develop moving heat source as the boundary heat flux acting interchangeably with the convective cooling terms. The difficulties accounted for the accurate simulation of heating during spin of the rotor is omitted by the use of the code, which enable shaping curves responsible for the thermal flux entering the disc at subsequent moments of time. The resulting evolution of temperature on the friction surface reveals a wide range of variations, distinguishing periods of heating and cooling states. It has been established, that during single braking the convective cooling has insignificant influence on the temperature distributions of a disc brake, consequently is not able to prevent overheat problem. However the brake release period after the braking operation, when the velocity of the vehicle remains on the same level, results in considerable decrease of temperature. - Highlights: → Convection does not allow to lower temperature of disc during single braking process. → Maximal temperature of disc decreases with number of brake applications. → Temperature at the end of braking increases with number of brake

  13. Three-dimensional FDEM numerical simulation of failure processes observed in Opalinus Clay laboratory samples

    Directory of Open Access Journals (Sweden)

    Omid Mahabadi

    2014-12-01

    Full Text Available This study presents the first step of a research project that aims at using a three-dimensional (3D hybrid finite-discrete element method (FDEM to investigate the development of an excavation damaged zone (EDZ around tunnels in a clay shale formation known as Opalinus Clay. The 3D FDEM was first calibrated against standard laboratory experiments, including Brazilian disc test and uniaxial compression test. The effect of increasing confining pressure on the mechanical response and fracture propagation of the rock was quantified under triaxial compression tests. Polyaxial (or true triaxial simulations highlighted the effect of the intermediate principal stress (σ2 on fracture directions in the model: as the intermediate principal stress increased, fractures tended to align in the direction parallel to the plane defined by the major and intermediate principal stresses. The peak strength was also shown to vary with changing σ2.

  14. Design and testing of indigenous cost effective three dimensional radiation field analyser (3D RFA).

    Science.gov (United States)

    Ganesh, K M; Pichandi, A; Nehru, R M; Ravikumar, M

    2014-06-01

    The aim of the study is to design and validate an indigenous three dimensional Radiation Field Analyser (3D RFA). The feed system made for X, Y and Z axis movements is of lead screw with deep ball bearing mechanism made up of stain less steel driven by stepper motors with accuracy less than 0.5 mm. The telescopic column lifting unit was designed using linear actuation technology for lifting the water phantom. The acrylic phantom with dimensions of 800 x 750 x 570 mm was made with thickness of 15 mm. The software was developed in visual basic programming language, classified into two types, viz. beam analyzer software and beam acquisition software. The premeasurement checks were performed as per TG 106 recommendations. The physical parameters of photon PDDs such as Dmax, D10, D20 and Quality Index (QI), and the electron PDDs such as R50, Rp, E0, Epo and X-ray contamination values can be obtained instantaneously by using the developed RFA system. Also the results for profile data such as field size, central axis deviation, penumbra, flatness and symmetry calculated according to various protocols can be obtained for both photon and electron beams. The result of PDDs for photon beams were compared with BJR25 supplement values and the profile data were compared with TG 40 recommendation. The results were in agreement with standard protocols.

  15. Three-dimensional cluster formation and structure in heterogeneous dose distribution of intensity modulated radiation therapy.

    Science.gov (United States)

    Chao, Ming; Wei, Jie; Narayanasamy, Ganesh; Yuan, Yading; Lo, Yeh-Chi; Peñagarícano, José A

    2018-05-01

    To investigate three-dimensional cluster structure and its correlation to clinical endpoint in heterogeneous dose distributions from intensity modulated radiation therapy. Twenty-five clinical plans from twenty-one head and neck (HN) patients were used for a phenomenological study of the cluster structure formed from the dose distributions of organs at risks (OARs) close to the planning target volumes (PTVs). Initially, OAR clusters were searched to examine the pattern consistence among ten HN patients and five clinically similar plans from another HN patient. Second, clusters of the esophagus from another ten HN patients were scrutinized to correlate their sizes to radiobiological parameters. Finally, an extensive Monte Carlo (MC) procedure was implemented to gain deeper insights into the behavioral properties of the cluster formation. Clinical studies showed that OAR clusters had drastic differences despite similar PTV coverage among different patients, and the radiobiological parameters failed to positively correlate with the cluster sizes. MC study demonstrated the inverse relationship between the cluster size and the cluster connectivity, and the nonlinear changes in cluster size with dose thresholds. In addition, the clusters were insensitive to the shape of OARs. The results demonstrated that the cluster size could serve as an insightful index of normal tissue damage. The clinical outcome of the same dose-volume might be potentially different. Copyright © 2018 Elsevier B.V. All rights reserved.

  16. Use of three-dimensional lognormal dose-response surfaces in lifetime studies of radiation-induced cancer

    International Nuclear Information System (INIS)

    Raabe, O.G.

    1986-01-01

    The three-dimensional lognormal cumulative probability power function was used to provide a unifying dose-response description of the lifetime cancer risk for chronic exposure of experimental animals and people, for risk evaluation, and for scaling between species. Bone tumor fatilities, primarily from alpha irradiation of the skeleton in lifetime studies of beagles injected with 226 Ra, were shown to be well described by this function. This function described cancer risk in lifetime studies as a curved smooth surface depending on radiation exposure rate and elapsed time, such that the principal risk at low dose rates occurred near the end of the normal life span without significant life shortening. Essentially identical functions with the median value of the power function displaced with respect to appropriate RBE values were shown to describe bone-cancer induction primarily from alpha irradiation of the skeleton in lifetime beagle studies with injected 226 Ra, 228 Th, 239 Pu and 241 Am, and with inhaled 238 Pu. Application of this model to human exposures to 226 Ra yielded a response ratio of 3.6; that is, the time required for development of bone cancer in people was 3.6 times longer than for beagles at the same average skeletal dose rate. It was suggested that similar techniques were appropriate to other carcinogens and other critical organs. 20 refs., 8 figs., 3 tabs

  17. The use of tubular retractors for translaminar discectomy for cranially and caudally extruded discs

    Directory of Open Access Journals (Sweden)

    Arvind G Kulkarni

    2018-01-01

    Full Text Available Background: The conventional interlaminar approach is adequate for access to most disc herniations in lumbar spine surgery. The access to cranially and caudally migrated disc fragments, by conventional interlaminar fenestration, requires an extension of the fenestration with the potential destruction of the facet joint complex and consequent postsurgical instability. To describe the technique and results of the translaminar technique of targeted discectomy using tubular retractors for the surgical treatment of cranially and caudally extruded discs. Materials and Methods: The study period extended from January 2008 to December 2014. All patients with lumbar herniated discs who failed conservative management were selected for surgery and underwent routine erect radiographs and magnetic resonance imaging (MRI of the lumbar spine. The patients with cranially or caudally migrated discs were included in this study. The technique involves approaching migrated disc through an oval window (sculpted through an 18 mm tubular retractor using a burr in the lamina precisely over the location of the migrated disc as predicted by the preoperative MRI (inferior lamina for inferior migration and superior lamina for superior migration. The perioperative parameters studied were operative time, blood loss, complications, Oswestry Disability Index (ODI, and visual analog scale (VAS for leg pain before surgery and at last followup. In the study, 4 patients underwent a postoperative computed tomography-scan with a three-dimensional reconstruction to visualize the oval window and to rule out any pars fracture. All technical difficulties and complications were analyzed. Results: 17 patients in the age group of 41–58 years underwent the translaminar technique of targeted discectomy. The migration of disc was cranial in 12 patients and caudal in 5 patients. Fourteen of the affected discs were at the L4–L5 level and three were at the L5-S1 level. The mean VAS (leg pain

  18. Three-dimensional CT of the pediatric spine

    International Nuclear Information System (INIS)

    Starshak, R.J.; Crawford, C.R.; Waisman, R.C.; Sty, J.R.

    1987-01-01

    CT of the spine has been shown to be useful in evaluating congenital, neoplastic, inflammatory, and traumatic lesions. Any portion of the neural arch may be involved by these disease processes. However, the complex nature of the spinal column can make evaluation of these abnormalities difficult on axial CT. This is especially true if the spine is distorted by scoliosis, kyphosis, or lordosis. The principal advantage of three-dimensional CT is its ability to display the surface relationships of complicated objects. The complexity of the spinal axis makes it ideal for study with three-dimensional CT. This presentation illustrates the advantages and drawbacks of three-dimensional CT in spinal abnormalities in children

  19. Biomechanics of a Fixed–Center of Rotation Cervical Intervertebral Disc Prosthesis

    Science.gov (United States)

    Crawford, Neil R.; Baek, Seungwon; Sawa, Anna G.U.; Safavi-Abbasi, Sam; Sonntag, Volker K.H.; Duggal, Neil

    2012-01-01

    Background Past in vitro experiments studying artificial discs have focused on range of motion. It is also important to understand how artificial discs affect other biomechanical parameters, especially alterations to kinematics. The purpose of this in vitro investigation was to quantify how disc replacement with a ball-and-socket disc arthroplasty device (ProDisc-C; Synthes, West Chester, Pennsylvania) alters biomechanics of the spine relative to the normal condition (positive control) and simulated fusion (negative control). Methods Specimens were tested in multiple planes by use of pure moments under load control and again in displacement control during flexion-extension with a constant 70-N compressive follower load. Optical markers measured 3-dimensional vertebral motion, and a strain gauge array measured C4-5 facet loads. Results Range of motion and lax zone after disc replacement were not significantly different from normal values except during lateral bending, whereas plating significantly reduced motion in all loading modes (P biomechanics were less substantial after artificial disc placement than after anterior plating. PMID:25694869

  20. Three-Dimensional Conformal Radiation Therapy and Intensity-Modulated Radiation Therapy Combined With Transcatheter Arterial Chemoembolization for Locally Advanced Hepatocellular Carcinoma: An Irradiation Dose Escalation Study

    International Nuclear Information System (INIS)

    Ren Zhigang; Zhao Jiandong; Gu Ke; Chen Zhen; Lin Junhua; Xu Zhiyong; Hu Weigang; Zhou Zhenhua; Liu Luming; Jiang Guoliang

    2011-01-01

    Purpose: To determine the maximum tolerated dose (MTD) of three-dimensional conformal radiation therapy (3DCRT)/intensity-modulated radiation therapy (IMRT) combined with transcatheter arterial chemoembolization for locally advanced hepatocellular carcinoma. Methods and Materials: Patients were assigned to two subgroups based on tumor diameter: Group 1 had tumors <10 cm; Group II had tumors ≥10 cm. Escalation was achieved by increments of 4.0 Gy for each cohort in both groups. Dose-limiting toxicity (DLT) was defined as a grade of ≥3 acute liver or gastrointestinal toxicity or any grade 5 acute toxicity in other organs at risk or radiation-induced liver disease. The dose escalation would be terminated when ≥2 of 8 patients in a cohort experienced DLT. Results: From April 2005 to May 2008, 40 patients were enrolled. In Group I, 11 patients had grade ≤2 acute treatment-related toxicities, and no patient experienced DLT; and in Group II, 10 patients had grade ≤2 acute toxicity, and 1 patient in the group receiving 52 Gy developed radiation-induced liver disease. MTD was 62 Gy for Group I and 52 Gy for Group II. In-field progression-free and local progression-free rates were 100% and 69% at 1 year, and 93% and 44% at 2 years, respectively. Distant metastasis rates were 6% at 1 year and 15% at 2 years. Overall survival rates for 1-year and 2-years were 72% and 62%, respectively. Conclusions: The irradiation dose was safely escalated in hepatocellular carcinoma patients by using 3DCRT/IMRT with an active breathing coordinator. MTD was 62 Gy and 52 Gy for patients with tumor diameters of <10 cm and ≥10 cm, respectively.

  1. Three-dimensional deformation of orthodontic brackets

    Science.gov (United States)

    Melenka, Garrett W; Nobes, David S; Major, Paul W

    2013-01-01

    Braces are used by orthodontists to correct the misalignment of teeth in the mouth. Archwire rotation is a particular procedure used to correct tooth inclination. Wire rotation can result in deformation to the orthodontic brackets, and an orthodontic torque simulator has been designed to examine this wire–bracket interaction. An optical technique has been employed to measure the deformation due to size and geometric constraints of the orthodontic brackets. Images of orthodontic brackets are collected using a stereo microscope and two charge-coupled device cameras, and deformation of orthodontic brackets is measured using a three-dimensional digital image correlation technique. The three-dimensional deformation of orthodontic brackets will be evaluated. The repeatability of the three-dimensional digital image correlation measurement method was evaluated by performing 30 archwire rotation tests using the same bracket and archwire. Finally, five Damon 3MX and five In-Ovation R self-ligating brackets will be compared using this technique to demonstrate the effect of archwire rotation on bracket design. PMID:23762201

  2. Three-dimensional deformation of orthodontic brackets.

    Science.gov (United States)

    Melenka, Garrett W; Nobes, David S; Major, Paul W; Carey, Jason P

    2013-01-01

    Braces are used by orthodontists to correct the misalignment of teeth in the mouth. Archwire rotation is a particular procedure used to correct tooth inclination. Wire rotation can result in deformation to the orthodontic brackets, and an orthodontic torque simulator has been designed to examine this wire-bracket interaction. An optical technique has been employed to measure the deformation due to size and geometric constraints of the orthodontic brackets. Images of orthodontic brackets are collected using a stereo microscope and two charge-coupled device cameras, and deformation of orthodontic brackets is measured using a three-dimensional digital image correlation technique. The three-dimensional deformation of orthodontic brackets will be evaluated. The repeatability of the three-dimensional digital image correlation measurement method was evaluated by performing 30 archwire rotation tests using the same bracket and archwire. Finally, five Damon 3MX and five In-Ovation R self-ligating brackets will be compared using this technique to demonstrate the effect of archwire rotation on bracket design.

  3. Three-dimensional plasma equilibrium near a separatrix

    International Nuclear Information System (INIS)

    Reiman, A.H.; Pomphrey, N.; Boozer, A.H.

    1988-08-01

    The limiting behavior of a general three-dimensional MHD equilibrium near a separatrix is calculated explicitly. No expansions in β or assumptions about island widths are made. Implications of the results for the numerical calculation of such equilibria, are discussed, as well as for issues concerning the existence of three-dimensional MHD equilibria. 16 refs., 2 figs

  4. Three-dimensional modeling of capsule implosions in OMEGA tetrahedral hohlraums

    International Nuclear Information System (INIS)

    Schnittman, J. D.; Craxton, R. S.

    2000-01-01

    Tetrahedral hohlraums have been proposed as a means for achieving the highly uniform implosions needed for ignition with inertial confinement fusion (ICF) [J. D. Schnittman and R. S. Craxton, Phys. Plasmas 3, 3786 (1996)]. Recent experiments on the OMEGA laser system have achieved good drive uniformity consistent with theoretical predictions [J. M. Wallace et al., Phys. Rev. Lett. 82, 3807 (1999)]. To better understand these experiments and future investigations of high-convergence ICF implosions, the three-dimensional (3-D) view-factor code BUTTERCUP has been expanded to model the time-dependent radiation transport in the hohlraum and the hydrodynamic implosion of the capsule. Additionally, a 3-D postprocessor has been written to simulate x-ray images of the imploded core. Despite BUTTERCUP's relative simplicity, its predictions for radiation drive temperatures, fusion yields, and core deformation show close agreement with experiment. (c) 2000 American Institute of Physics

  5. Vascular complications of prosthetic inter-vertebral discs.

    Science.gov (United States)

    Daly, Kevin J; Ross, E Raymond S; Norris, Heather; McCollum, Charles N

    2006-10-01

    Five consecutive cases of prosthetic inter-vertebral disc displacement with severe vascular complications on revisional surgery are described. The objective of this case report is to warn spinal surgeons that major vascular complications are likely with anterior displacement of inter-vertebral discs. We have not been able to find a previous report on vascular complications associated with anterior displacement of prosthetic inter-vertebral discs. In all five patients the prosthetic disc had eroded into the bifurcation of the inferior vena cava and the left common iliac vein. In three cases the aortic bifurcation was also involved. The fibrosis was so severe that dissecting out the arteries and veins to provide access to the relevant disc proved impossible. Formal division of the left common iliac vein and artery with subsequent repair was our solution. Anterior inter-vertebral disc displacement was associated with severe vascular injury. Preventing anterior disc displacement is essential in disc design. In the event of anterior displacement, disc removal should be planned with a Vascular Surgeon.

  6. Advancing three-dimensional MEMS by complimentary laser micro manufacturing

    Science.gov (United States)

    Palmer, Jeremy A.; Williams, John D.; Lemp, Tom; Lehecka, Tom M.; Medina, Francisco; Wicker, Ryan B.

    2006-01-01

    This paper describes improvements that enable engineers to create three-dimensional MEMS in a variety of materials. It also provides a means for selectively adding three-dimensional, high aspect ratio features to pre-existing PMMA micro molds for subsequent LIGA processing. This complimentary method involves in situ construction of three-dimensional micro molds in a stand-alone configuration or directly adjacent to features formed by x-ray lithography. Three-dimensional micro molds are created by micro stereolithography (MSL), an additive rapid prototyping technology. Alternatively, three-dimensional features may be added by direct femtosecond laser micro machining. Parameters for optimal femtosecond laser micro machining of PMMA at 800 nanometers are presented. The technical discussion also includes strategies for enhancements in the context of material selection and post-process surface finish. This approach may lead to practical, cost-effective 3-D MEMS with the surface finish and throughput advantages of x-ray lithography. Accurate three-dimensional metal microstructures are demonstrated. Challenges remain in process planning for micro stereolithography and development of buried features following femtosecond laser micro machining.

  7. Mechanoreceptors in Diseased Cervical Intervertebral Disc and Vertigo.

    Science.gov (United States)

    Yang, Liang; Yang, Cheng; Pang, Xiaodong; Li, Duanming; Yang, Hong; Zhang, Xinwu; Yang, Yi; Peng, Baogan

    2017-04-15

    We collected the samples of cervical intervertebral discs from patients with vertigo to examine the distribution and types of mechanoreceptors in diseased cervical disc. The aim of this study was to determine whether mechanoreceptors are distributed more abundantly in cervical discs from patients with cervical spondylosis, and whether they are related to vertigo. Previous limited studies have found that normal cervical intervertebral discs are supplied with mechanoreceptors that have been considered responsible for proprioceptive functions. Several clinical studies have indicated that the patients with cervical spondylosis manifested significantly impaired postural control and subjective balance disturbance. We collected 77 samples of cervical discs from 62 cervical spondylosis patients without vertigo, 61 samples from 54 patients with vertigo, and 40 control samples from 8 cadaveric donors to investigate distribution of mechanoreceptors containing neurofilament (NF200) and S-100 protein immunoreactive nerve endings. The immunohistochemical investigation revealed that the most frequently encountered mechanoreceptors were the Ruffini corpuscles in all groups of cervical disc samples. They were obviously increased in the number and deeply ingrown into inner annulus fibrosus and even into nucleus pulposus in the diseased cervical discs from patients with vertigo in comparison with the discs from patients without vertigo and control discs. Only three Golgi endings were seen in the three samples from patients with vertigo. No Pacinian corpuscles were found in any samples of cervical discs. The diseased cervical discs from patients with vertigo had more abundant distribution of Ruffini corpuscles than other discs. A positive association between the increased number and ingrowth of Ruffini corpuscles in the diseased cervical disc and the incidence of vertigo in the patients with cervical spondylosis was found, which may indicate a key role of Ruffini corpuscles in the

  8. On two-dimensionalization of three-dimensional turbulence in shell models

    DEFF Research Database (Denmark)

    Chakraborty, Sagar; Jensen, Mogens Høgh; Sarkar, A.

    2010-01-01

    Applying a modified version of the Gledzer-Ohkitani-Yamada (GOY) shell model, the signatures of so-called two-dimensionalization effect of three-dimensional incompressible, homogeneous, isotropic fully developed unforced turbulence have been studied and reproduced. Within the framework of shell m......-similar PDFs for longitudinal velocity differences are also presented for the rotating 3D turbulence case....

  9. Comparison of Animal Discs Used in Disc Research to Human Lumbar Disc: Torsion Mechanics and Collagen Content

    Science.gov (United States)

    Showalter, Brent L.; Beckstein, Jesse C.; Martin, John T.; Beattie, Elizabeth E.; Orías, Alejandro A. Espinoza; Schaer, Thomas P.; Vresilovic, Edward J.; Elliott, Dawn M.

    2012-01-01

    Study Design Experimental measurement and normalization of in vitro disc torsion mechanics and collagen content for several animal species used in intervertebral disc research and comparing these to the human disc. Objective To aid in the selection of appropriate animal models for disc research by measuring torsional mechanical properties and collagen content. Summary of Background Data There is lack of data and variability in testing protocols for comparing animal and human disc torsion mechanics and collagen content. Methods Intervertebral disc torsion mechanics were measured and normalized by disc height and polar moment of inertia for 11 disc types in 8 mammalian species: the calf, pig, baboon, goat, sheep, rabbit, rat, and mouse lumbar, and cow, rat, and mouse caudal. Collagen content was measured and normalized by dry weight for the same discs except the rat and mouse. Collagen fiber stretch in torsion was calculated using an analytical model. Results Measured torsion parameters varied by several orders of magnitude across the different species. After geometric normalization, only the sheep and pig discs were statistically different from human. Fiber stretch was found to be highly dependent on the assumed initial fiber angle. The collagen content of the discs was similar, especially in the outer annulus where only the calf and goat discs were statistically different from human. Disc collagen content did not correlate with torsion mechanics. Conclusion Disc torsion mechanics are comparable to human lumbar discs in 9 of 11 disc types after normalization by geometry. The normalized torsion mechanics and collagen content of the multiple animal discs presented is useful for selecting and interpreting results for animal models of the disc. Structural composition of the disc, such as initial fiber angle, may explain the differences that were noted between species after geometric normalization. PMID:22333953

  10. Promising survival with three-dimensional conformal radiation therapy for non-small cell lung cancer

    International Nuclear Information System (INIS)

    Armstrong, John; Raben, Adam; Zelefsky, Michael; Burt, Michael; Leibel, Steve; Burman, Chandra; Kutcher, Gerard; Harrison, Louis; Hahn, Cathy; Ginsberg, Robert; Rusch, Valerie; Kris, Mark; Fuks, Zvi

    1997-01-01

    Purpose: Local failure is a major obstacle to the cure of locally advanced non small-cell lung cancer. Three-dimensional conformal radiation therapy (3-DCRT) selects optimal treatment parameters to increase dose to tumor and reduce normal tissue dose, potentially representing an enhancement of the therapeutic ratio of radiation therapy for lung cancer. We performed this analysis of 45 non-small cell lung cancer patients treated with 3-DCRT alone, to evaluate the ability of computer derived lung dose volume histograms to predict serious pulmonary toxicity, to assess the feasibility of this approach, and to examine the resulting survival. Methods: There were 28 males (62%) and 17 females (38%). The median age was 65 (range: 38-82). Tumor stage was Stage I/II in 13%, IIIa in 42%, and IIIb in 44%. The histology was squamous in 44%, adenocarcinoma in 36%, and other non-small cell histologies in the others. Only 47% of patients. had combined favorable prognostic factors (i.e. KPS ≤ 80, and ≤5% wt. loss). The median dose of radiation to gross disease was 70.2 Gy (range: 52.2-72 Gy) delivered in fractions of 1.8 Gy, 5 days per week. Results: Seven patients did not complete 3-DCRT due to disease progression outside the port. Follow-up data are mature: the median follow up of the 6 survivors is 43.5 months (35-59). Thoracic progression occurred in 46%. Median survival (all 45 patients.) is 15.7 months and survival is 32% at 2 years and 12% at 59 months. Pulmonary toxicity ≥grade 3 occurred in 9% of patients. Dose volume histograms were available in 31 patients and showed a correlation between risk of pulmonary toxicity and indices of dose to lung parenchyma. Grade 3 or higher pulmonary toxicity occurred in 38% ((3(8))) of patients with >30% of lung volume receiving ≥25 Gy, versus 4% ((1(23))) of patients with ≤30% lung receiving ≥25 Gy (P = 0.04). Grade 3 or higher pulmonary toxicity occurred in 29% ((4(14))) of patients with a predicted pulmonary normal tissue

  11. COSMO-PAFOG: Three-dimensional fog forecasting with the high-resolution COSMO-model

    Science.gov (United States)

    Hacker, Maike; Bott, Andreas

    2017-04-01

    The presence of fog can have critical impact on shipping, aviation and road traffic increasing the risk of serious accidents. Besides these negative impacts of fog, in arid regions fog is explored as a supplementary source of water for human settlements. Thus the improvement of fog forecasts holds immense operational value. The aim of this study is the development of an efficient three-dimensional numerical fog forecast model based on a mesoscale weather prediction model for the application in the Namib region. The microphysical parametrization of the one-dimensional fog forecast model PAFOG (PArameterized FOG) is implemented in the three-dimensional nonhydrostatic mesoscale weather prediction model COSMO (COnsortium for Small-scale MOdeling) developed and maintained by the German Meteorological Service. Cloud water droplets are introduced in COSMO as prognostic variables, thus allowing a detailed description of droplet sedimentation. Furthermore, a visibility parametrization depending on the liquid water content and the droplet number concentration is implemented. The resulting fog forecast model COSMO-PAFOG is run with kilometer-scale horizontal resolution. In vertical direction, we use logarithmically equidistant layers with 45 of 80 layers in total located below 2000 m. Model results are compared to satellite observations and synoptic observations of the German Meteorological Service for a domain in the west of Germany, before the model is adapted to the geographical and climatological conditions in the Namib desert. COSMO-PAFOG is able to represent the horizontal structure of fog patches reasonably well. Especially small fog patches typical of radiation fog can be simulated in agreement with observations. Ground observations of temperature are also reproduced. Simulations without the PAFOG microphysics yield unrealistically high liquid water contents. This in turn reduces the radiative cooling of the ground, thus inhibiting nocturnal temperature decrease. The

  12. Three-dimensional, two-species magnetohydrodynamic studies of the early time behaviors of the Combined Release and Radiation Effects Satellite G2 barium release

    International Nuclear Information System (INIS)

    Xie, Lianghai; Li, Lei; Wang, Jingdong; Zhang, Yiteng

    2014-01-01

    We present a three-dimensional, two-species (Ba + and H + ) MHD model to study the early time behaviors of a barium release at about 1 R E like Combined Release and Radiation Effects Satellite G2, with emphasis placed on the three-dimensional evolution of the barium cloud and its effects on the ambient plasma environment. We find that the perturbations caused by the cloud are the combined results of the initial injection, the radial expansion, and the diamagnetic effect and propagate as fast MHD waves in the magnetosphere. In return, the transverse expansion and the cross-B motion of barium ions are constrained by the magnetic force, which lead to a field-aligned striation of ions and the decoupling of these ions from the neutrals. Our simulation shows the formation and collapse of the diamagnetic cavity in the barium cloud. The estimated time scale for the cavity evolution might be much shorter if photoionization time scale and field aligned expansion of barium ions are considered. In addition, our two species MHD simulation also finds the snowplow effect resulting from the momentum coupling between barium ions and background H + , which creates density hole and bumps in the background H + when barium ions expanding along the magnetic field lines

  13. Computational study of three-dimensional wake structure

    International Nuclear Information System (INIS)

    Himeno, R.; Shirayama, S.; Kamo, K.; Kuwahara, K.

    1986-01-01

    Three-dimensional wake structure is studied by numerically solving the incompressible Navier-Stokes equations. Results are visualized by a three-dimensional color graphic system. It was found that a pair of vortex tubes separated from a body plays the most important role in the wake. Near the body vortex tubes are rather stable, however, they gradually become unsteady as they flow down

  14. Standalone visualization tool for three-dimensional DRAGON geometrical models

    International Nuclear Information System (INIS)

    Lukomski, A.; McIntee, B.; Moule, D.; Nichita, E.

    2008-01-01

    DRAGON is a neutron transport and depletion code able to solve one-, two- and three-dimensional problems. To date DRAGON provides two visualization modules, able to represent respectively two- and three-dimensional geometries. The two-dimensional visualization module generates a postscript file, while the three dimensional visualization module generates a MATLAB M-file with instructions for drawing the tracks in the DRAGON TRACKING data structure, which implicitly provide a representation of the geometry. The current work introduces a new, standalone, tool based on the open-source Visualization Toolkit (VTK) software package which allows the visualization of three-dimensional geometrical models by reading the DRAGON GEOMETRY data structure and generating an axonometric image which can be manipulated interactively by the user. (author)

  15. SNAP - a three dimensional neutron diffusion code

    International Nuclear Information System (INIS)

    McCallien, C.W.J.

    1993-02-01

    This report describes a one- two- three-dimensional multi-group diffusion code, SNAP, which is primarily intended for neutron diffusion calculations but can also carry out gamma calculations if the diffusion approximation is accurate enough. It is suitable for fast and thermal reactor core calculations and for shield calculations. SNAP can solve the multi-group neutron diffusion equations using finite difference methods. The one-dimensional slab, cylindrical and spherical geometries and the two-dimensional case are all treated as simple special cases of three-dimensional geometries. Numerous reflective and periodic symmetry options are available and may be used to reduce the number of mesh points necessary to represent the system. Extrapolation lengths can be specified at internal and external boundaries. (Author)

  16. Three-dimensional fluorescence lifetime tomography

    International Nuclear Information System (INIS)

    Godavarty, Anuradha; Sevick-Muraca, Eva M.; Eppstein, Margaret J.

    2005-01-01

    Near-infrared fluorescence tomography using molecularly targeted lifetime-sensitive, fluorescent contrast agents have applications for early-stage cancer diagnostics. Yet, although the measurement of fluorescent lifetime imaging microscopy (FLIM) is extensively used in microscopy and spectroscopy applications, demonstration of fluorescence lifetime tomography for medical imaging is limited to two-dimensional studies. Herein, the feasibility of three-dimensional fluorescence-lifetime tomography on clinically relevant phantom volumes is established, using (i) a gain-modulated intensified charge coupled device (CCD) and modulated laser diode imaging system, (ii) two fluorescent contrast agents, e.g., Indocyanine green and 3-3'-Diethylthiatricarbocyanine iodide differing in their fluorescence lifetime by 0.62 ns, and (iii) a two stage approximate extended Kalman filter reconstruction algorithm. Fluorescence measurements of phase and amplitude were acquired on the phantom surface under different target to background fluorescence absorption (70:1, 100:1) and fluorescence lifetime (1:1, 2.1:1) contrasts at target depths of 1.4-2 cm. The Bayesian tomography algorithm was employed to obtain three-dimensional images of lifetime and absorption owing to the fluorophores

  17. Three-dimensional analysis of harmonic generation in high-gain free-electron lasers

    International Nuclear Information System (INIS)

    Huang, Zhirong; Kim, Kwang-Je

    2000-01-01

    In a high-gain free-electron laser (FEL) employing a planar undulator, strong bunching at the fundamental wavelength can drive substantial bunching and power levels at the harmonic frequencies. In this paper we investigate the three-dimensional evolution of harmonic radiation based on the coupled Maxwell-Klimontovich equations that take into account nonlinear harmonic interactions. Each harmonic field is a sum of a linear amplification term and a term driven by nonlinear harmonic interactions. After a certain stage of exponential growth, the dominant nonlinear term is determined by interactions of the lower nonlinear harmonics and the fundamental radiation. As a result, the gain length, transverse profile, and temporal structure of the first few harmonics are eventually governed by those of the fundamental. Transversely coherent third-harmonic radiation power is found to approach 1% of the fundamental power level for current high-gain FEL projects

  18. Intervertebral Disc Characteristic on Progressive Neurological Deficit

    Directory of Open Access Journals (Sweden)

    Farid Yudoyono

    2017-09-01

    Full Text Available Objective: To examine the intervertebral disc characteristic on magnetic resonance imaging (MRI in lumbar herniated disc (LHD patients with progressive neurological deficit. Methods: Patients were collected retrospectively from Dr. Hasan Sadikin General Hospital Database from 2011–2013 with LHD, had neurological deficit such as radiculopathy and cauda equine syndrome for less than four weeks with a positive sign confirmed by neurological examination and confirmatory with MRI examination. Results: A total of 14 patients with lumbar herniated disc disease (10 males, 4 females suffered from progressive neurological deficit with an average age of (52.07±10.9 years old. Early disc height was 9.38±0.5 mm and progressive neurological deficit state disc height was 4.03±0.53 mm, which were significantly different statisticaly (p<0.01. Symptoms of radiculopathy were seen in 11 patients and cauda equine syndrome in three patients. Modic changes grade 1 was found in five patients, grade 2 in eight patients,grade 3 in one patient, Pfirmman grade 2 in eleven patients and grade 3 in three patients. Thecal sac compression 1/3 compression was seen in four patients and 2/3 compression in ten patients. Conclusions: Neurosurgeon should raise concerns on the characteristic changes of intervertebral disc in magnetic resonance imaging examination to avoid further neural injury in lumbar herniated disc patients.

  19. Three-dimensional photography for the evaluation of facial profiles in obstructive sleep apnoea.

    Science.gov (United States)

    Lin, Shih-Wei; Sutherland, Kate; Liao, Yu-Fang; Cistulli, Peter A; Chuang, Li-Pang; Chou, Yu-Ting; Chang, Chih-Hao; Lee, Chung-Shu; Li, Li-Fu; Chen, Ning-Hung

    2018-06-01

    Craniofacial structure is an important determinant of obstructive sleep apnoea (OSA) syndrome risk. Three-dimensional stereo-photogrammetry (3dMD) is a novel technique which allows quantification of the craniofacial profile. This study compares the facial images of OSA patients captured by 3dMD to three-dimensional computed tomography (3-D CT) and two-dimensional (2-D) digital photogrammetry. Measurements were correlated with indices of OSA severity. Thirty-eight patients diagnosed with OSA were included, and digital photogrammetry, 3dMD and 3-D CT were performed. Distances, areas, angles and volumes from the images captured by three methods were analysed. Almost all measurements captured by 3dMD showed strong agreement with 3-D CT measurements. Results from 2-D digital photogrammetry showed poor agreement with 3-D CT. Mandibular width, neck perimeter size and maxillary volume measurements correlated well with the severity of OSA using all three imaging methods. Mandibular length, facial width, binocular width, neck width, cranial base triangle area, cranial base area 1 and middle cranial fossa volume correlated well with OSA severity using 3dMD and 3-D CT, but not with 2-D digital photogrammetry. 3dMD provided accurate craniofacial measurements of OSA patients, which were highly concordant with those obtained by CT, while avoiding the radiation associated with CT. © 2018 Asian Pacific Society of Respirology.

  20. Three-dimensional optofluidic device for isolating microbes

    Science.gov (United States)

    Keloth, A.; Paterson, L.; Markx, G. H.; Kar, A. K.

    2015-03-01

    Development of efficient methods for isolation and manipulation of microorganisms is essential to study unidentified and yet-to-be cultured microbes originating from a variety of environments. The discovery of novel microbes and their products have the potential to contribute to the development of new medicines and other industrially important bioactive compounds. In this paper we describe the design, fabrication and validation of an optofluidic device capable of redirecting microbes within a flow using optical forces. The device holds promise to enable the high throughput isolation of single microbes for downstream culture and analysis. Optofluidic devices are widely used in clinical research, cell biology and biomedical engineering as they are capable of performing analytical functions such as controlled transportation, compact and rapid processing of nanolitres to millilitres of clinical or biological samples. We have designed and fabricated a three dimensional optofluidic device to control and manipulate microorganisms within a microfluidic channel. The device was fabricated in fused silica by ultrafast laser inscription (ULI) followed by selective chemical etching. The unique three-dimensional capability of ULI is utilized to integrate microfluidic channels and waveguides within the same substrate. The main microfluidic channel in the device constitutes the path of the sample. Optical waveguides are fabricated at right angles to the main microfluidic channel. The potential of the optical scattering force to control and manipulate microorganisms is discussed in this paper. A 980 nm continuous wave (CW) laser source, coupled to the waveguide, is used to exert radiation pressure on the particle and particle migrations at different flow velocities are recorded. As a first demonstration, device functionality is validated using fluorescent microbeads and initial trials with microalgae are presented.

  1. SU-E-T-752: Three-Dimensional Carcinogenic Maps Induced by Photons and Protons

    Energy Technology Data Exchange (ETDEWEB)

    Manem, V; Paganetti, H [Massachusetts General Hospital, Boston, MA (United States)

    2015-06-15

    Purpose: Evaluate the excess relative risk (ERR) induced by photons and protons in each voxel of the lung, and display it as a three-dimensional map, known as the ERRM (i.e. excess relative risk map) along with the dose distribution map. In addition, we also study the effect of variations in the linear energy transfer (LET) distribution on ERRM for a given proton plan. Methods: The excess relative risk due to radiation is estimated using the initiation-inactivation-proliferation formalism. This framework accounts for three biological phenomenon: mutation induction, cell kill and proliferation. Cell kill and mutation induction are taken as a function of LET using experimental data. LET distributions are calculated using a Monte Carlo algorithm. ERR is then estimated for each voxel in the organ, and displayed as a three dimensional carcinogenic map. Results: The differences in the ERR’s between photons and protons is seen from the three-dimensional ERR map. In addition, we also varied the LET of a proton plan and observed the differences in the corresponding ERR maps demonstrating variations in the ERR maps depend on features of a proton plan. Additionally, our results suggest that any two proton plans that have the same integral dose does not necessarily imply identical ERR maps, and these changes are due to the variations in the LET distribution map. Conclusion: Clinically, it is important to have a three dimensional display of biological end points. This study is an effort to introduce 3D ERR maps into the treatment planning workflow for certain sites such as pediatric head and neck tumors.

  2. Risk factors of radiation-induced liver disease after three-dimensional conformal radiotherapy for primary liver carcinoma

    International Nuclear Information System (INIS)

    Liang Shixiong; Zhu Xiaodong; Lu Haijie; Pan Chaoyang; Huang Qifang; Li Fuxiang; Wang Anyu; Liang Guoliang; Fu Xiaolong

    2005-01-01

    Objective: To identify the risk factors of radiation-induced liver disease (RILD) after three-dimensional radiotherapy (3DCRT) for primary liver carcinoma (PLC) and the dosimetric threshold of RILD. Methods: Between April 1999 and August 2003, 128 PLC patients who were treated with 3DCRT received a mean dose of 53.6 ± 6.6 Gy with a 4-8 Gy/f, 3f/w, qod regimen. The relation between RILD and the possible clinical factors, such as gender, age, UICC/ AJCC T stage, GTV, HBV status, PTV, TACE, Child-Pugh grade of liver cirrhosis, BED calculated by LQ model and fraction size were analyzed. Among 84 patients who had full dose- volume histogram (DVH) data, the relation between RILD and dosimetric parameters were analyzed. Results: Nineteen patients (14.8%) developed RILD. It was found that T stage, GTV, PTV, Child-Pugh grade of liver cirrhosis and the acute hepatic toxicity proposed by common toxicity criteria version 2.0 (CTC2.0) were correlated with RILD (P=0.024, 0.002, 0.001, 0.000, 0.000, respectively). Multivariate analysis showed that only the Child-Pugh grade of liver cirrhosis was independent factor (P=0.000). The mean liver dose was significantly higher in patients with RILD (P=0.027). In patients with Child-Pugh grade A, V5 (percentage of normal liver volume with radiation dose > 5 Gy), V 10 and V 20 ≤81%, 69% and 42%, mean liver dose ≤28 Gy, RILD was not observed, whereas in patients with Child-Pugh grade B, the possibility of developing RILD was 53.3%(8/15). Conclusions: Comprehensive consideration of T stage, GTV, PTV and Child-Pugh grade of liver cirrhosis, especially the Child-Pugh grade of liver cirrhosis, when planning 3DCRT for PLC, may lower the incidence of RILD. (authors)

  3. Development of three dimensional solid modeler

    International Nuclear Information System (INIS)

    Zahoor, R.M.A.

    1999-01-01

    The work presented in this thesis is aimed at developing a three dimensional solid modeler employing computer graphics techniques using C-Language. Primitives have been generated, by combination of plane surfaces, for various basic geometrical shapes including cylinder, cube and cone. Back face removal technique for hidden surface removal has also been incorporated. Various transformation techniques such as scaling, translation, and rotation have been included for the object animation. Three dimensional solid modeler has been created by the union of two primitives to demonstrate the capabilities of the developed program. (author)

  4. Three-dimensional concentration of light in deeply sub-wavelength, laterally tapered gap-plasmon nanocavities

    Energy Technology Data Exchange (ETDEWEB)

    Tagliabue, Giulia [Laboratory of Thermodynamics in Emerging Technologies, ETH Zurich, Zurich 8092 (Switzerland); Thomas J. Watson, Sr. Laboratories of Applied Physics, California Institute of Technology, Pasadena, California 91125 (United States); Poulikakos, Dimos; Eghlidi, Hadi, E-mail: eghlidim@ethz.ch [Laboratory of Thermodynamics in Emerging Technologies, ETH Zurich, Zurich 8092 (Switzerland)

    2016-05-30

    Gap-plasmons (GP) in metal-insulator-metal (MIM) structures have shown exceptional performance in guiding and concentrating light within deep subwavelength layers. Reported designs to date exploit tapered thicknesses of the insulating layer in order to confine and focus the GP mode. Here, we propose a mechanism for the three dimensional concentration of light in planar MIM structures which exploits exclusively the lateral tapering of the front metallic layer while keeping a constant thickness of the insulating layer. We demonstrate that an array of tapered planar GP nanocavities can efficiently concentrate light in all three dimensions. A semi-analytical, one-dimensional model provides understanding of the underlying physics and approximately predicts the behavior of the structure. Three-dimensional simulations are then used to precisely calculate the optical behavior. Cavities with effective volumes as small as 10{sup −5} λ{sup 3} are achieved in an ultrathin MIM configuration. Our design is inherently capable of efficiently coupling with free-space radiation. In addition, being composed of two electrically continuous layers separated by an ultrathin dielectric spacer, it could find interesting applications in the area of active metamaterials or plasmonic photocatalysis where both electrical access and light concentration are required.

  5. LIDT-DD: A New Self-Consistent Debris Disc Model Including Radiation Pressure and Coupling Dynamical and Collisional Evolution

    Science.gov (United States)

    Kral, Q.; Thebault, P.; Charnoz, S.

    2014-01-01

    The first attempt at developing a fully self-consistent code coupling dynamics and collisions to study debris discs (Kral et al. 2013) is presented. So far, these two crucial mechanisms were studied separately, with N-body and statistical collisional codes respectively, because of stringent computational constraints. We present a new model named LIDT-DD which is able to follow over long timescales the coupled evolution of dynamics (including radiation forces) and collisions in a self-consistent way.

  6. Artificial Disc Replacement

    Science.gov (United States)

    ... Spondylolisthesis BLOG FIND A SPECIALIST Treatments Artificial Disc Replacement (ADR) Patient Education Committee Jamie Baisden The disc ... Disc An artificial disc (also called a disc replacement, disc prosthesis or spine arthroplasty device) is a ...

  7. Three dimensional diffusion calculations of nuclear reactors

    International Nuclear Information System (INIS)

    Caspo, N.

    1981-07-01

    This work deals with the three dimensional calculation of nuclear reactors using the code TRITON. The purposes of the work were to perform three-dimensional computations of the core of the Soreq nuclear reactor and of the power reactor ZION and to validate the TRITON code. Possible applications of the TRITON code in Soreq reactor calculations and in power reactor research are suggested. (H.K.)

  8. A three-dimensional methodology for the assessment of neutron damage and nuclear energy deposition in graphite components of advanced gas-cooled reactors

    Energy Technology Data Exchange (ETDEWEB)

    Morgan, D.O.; Robinson, A.T.; Allen, D.A.; Picton, D.J.; Thornton, D.A. [TCS, Serco, Rutherford House, Olympus Park, Quedgeley, Gloucester, Gloucestershire GL2 4NF (United Kingdom); Shaw, S.E. [EDF Energy, Barnet Way, Barnwood, Gloucester GL4 3RS (United Kingdom)

    2011-07-01

    This paper describes the development of a three-dimensional methodology for the assessment of neutron damage and nuclear energy deposition (or nuclear heating) throughout the graphite cores of the UK's Advanced Gas-cooled Reactors. Advances in the development of the Monte Carlo radiation transport code MCBEND have enabled the efficient production of detailed fully three-dimensional models that utilise three-dimensional source distributions obtained from Core Follow data supplied by the reactor physics code PANTHER. The calculational approach can be simplified to reduce both the requisite number of intensive radiation transport calculations, as well as the quantity of data output. These simplifications have been qualified by comparison with explicit calculations and they have been shown not to introduce significant systematic uncertainties. Simple calculational approaches are described that allow users of the data to address the effects on neutron damage and nuclear energy deposition predictions of the feedback resulting from the mutual dependencies of graphite weight loss and nuclear energy deposition. (authors)

  9. Study of three-dimensional image display by systemic CT

    International Nuclear Information System (INIS)

    Fujioka, Tadao; Ebihara, Yoshiyuki; Unei, Hiroshi; Hayashi, Masao; Shinohe, Tooru; Wada, Yuji; Sakai, Takatsugu; Kashima, Kenji; Fujita, Yoshihiro

    1989-01-01

    A head phantom for CT was scanned at 2 mm intervals from the cervix to the vertex in an attempt to obtain a three-dimensional image display of bones and facial epidermis from an ordinary axial image. Clinically, three-dimensional images were formed at eye sockets and hip joints. With the three-dimensional image using the head phantom, the entire head could be displayed at any angle. Clinically, images were obtained that could not be attained by ordinary CT scanning, such as broken bones in eye sockets and stereoscopic structure at the bottom of a cranium. The three-dimensional image display is considered to be useful in clinical diagnosis. (author)

  10. Continuum modeling of three-dimensional truss-like space structures

    Science.gov (United States)

    Nayfeh, A. H.; Hefzy, M. S.

    1978-01-01

    A mathematical and computational analysis capability has been developed for calculating the effective mechanical properties of three-dimensional periodic truss-like structures. Two models are studied in detail. The first, called the octetruss model, is a three-dimensional extension of a two-dimensional model, and the second is a cubic model. Symmetry considerations are employed as a first step to show that the specific octetruss model has four independent constants and that the cubic model has two. The actual values of these constants are determined by averaging the contributions of each rod element to the overall structure stiffness. The individual rod member contribution to the overall stiffness is obtained by a three-dimensional coordinate transformation. The analysis shows that the effective three-dimensional elastic properties of both models are relatively close to each other.

  11. Disc size regulation in the brood cell building behavior of leaf-cutter bee, Megachile tsurugensis.

    Science.gov (United States)

    Kim, Jong-yoon

    2007-12-01

    The leaf-cutter bee, Megachile tsurugensis, builds a brood cell in a preexisting tunnel with leaf discs that she cuts in decreasing sizes and assembles them like a Russian matryoshka doll. By experimentally manipulating the brood cell, it was investigated how she regulates the size of leaf discs that fit in the brood cell's internal volume. When the internal volume was artificially increased by removing a bulk of leaf discs, she decreased the leaf disc size, although increasing it would have made the leaf disc more fitting in the increased internal volume. As a reverse manipulation, when the internal volume was decreased by inserting a group of inner layers of preassembled leaf discs to a brood cell, she decreased the leaf disc size, so that the leaf disc could fit in the decreased internal volume. These results suggest that she uses at least two different mechanisms to regulate the disc size: the use of some internal memory about the degree of building work accomplished in the first and of sensory feedback of dimensional information at the construction site in the second manipulation, respectively. It was concluded that a stigmergic mechanism, an immediate sensory feedback from the brood cell changed by the building work, alone cannot explain the details of the bee's behavior particularly with respect to her initial response to the first manipulation. For a more complete explanation of the behavior exhibited by the solitary bee, two additional behavioral elements, reinforcement of building activity and processing of dimensional information, were discussed along with stigmergy.

  12. Structural and Contact Analysis of a 3-Dimensional Disc-Pad Model with and without Thermal Effects

    Directory of Open Access Journals (Sweden)

    A. Belhocine

    2014-12-01

    Full Text Available The motivation of this work is to identify thermal effects on the structural and contact behaviour of a disc-pad assembly using a finite element approach. The first analysis is performed on the disc-pad model without the presence of thermal properties. Structural performance of the disc-pad model such as deformation and Von Mises stress is predicted. Next, thermomechanical analysis is performed on the same disc-pad model with the inclusion of convection, adiabatic and heat flux elements. The prediction results of temperature distribution, deformation, stress and contact pressure are presented. Comparison of the structural performance between the two analyses (mechanical and thermomechanical is also made. From this study, it can assist brake engineers to choose a suitable analysis in order to critically evaluate structural and contact behaviour of the disc brake assembly.

  13. Three-dimensional simulations of resistance spot welding

    DEFF Research Database (Denmark)

    Nielsen, Chris Valentin; Zhang, Wenqi; Perret, William

    2014-01-01

    This paper draws from the fundamentals of electro-thermo-mechanical coupling to the main aspects of finite element implementation and three-dimensional modelling of resistance welding. A new simulation environment is proposed in order to perform three-dimensional simulations and optimization...... of resistance welding together with the simulations of conventional and special-purpose quasi-static mechanical tests. Three-dimensional simulations of resistance welding consider the electrical, thermal, mechanical and metallurgical characteristics of the material as well as the operating conditions...... of the welding machines. Simulations of the mechanical tests take into account material softening due to the accumulation of ductile damage and cover conventional tests, such as tensile–shear tests, cross-tension test and peel tests, as well as the possibility of special-purpose tests designed by the users...

  14. Observations and simulations of three-dimensional radiative interactions between Arctic boundary layer clouds and ice floes

    Science.gov (United States)

    Schäfer, M.; Bierwirth, E.; Ehrlich, A.; Jäkel, E.; Wendisch, M.

    2015-01-01

    Based on airborne spectral imaging observations three-dimensional (3-D) radiative effects between Arctic boundary layer clouds and ice floes have been identified and quantified. A method is presented to discriminate sea ice and open water in case of clouds from imaging radiance measurements. This separation simultaneously reveals that in case of clouds the transition of radiance between open water and sea ice is not instantaneously but horizontally smoothed. In general, clouds reduce the nadir radiance above bright surfaces in the vicinity of sea ice - open water boundaries, while the nadir radiance above dark surfaces is enhanced compared to situations with clouds located above horizontal homogeneous surfaces. With help of the observations and 3-D radiative transfer simulations, this effect was quantified to range between 0 and 2200 m distance to the sea ice edge. This affected distance Δ L was found to depend on both, cloud and sea ice properties. For a ground overlaying cloud in 0-200 m altitude, increasing the cloud optical thickness from τ = 1 to τ = 10 decreases Δ L from 600 to 250 m, while increasing cloud base altitude or cloud geometrical thickness can increase Δ L; Δ L(τ = 1/10) = 2200 m/1250 m for 500-1000 m cloud altitude. To quantify the effect for different shapes and sizes of the ice floes, various albedo fields (infinite straight ice edge, circles, squares, realistic ice floe field) were modelled. Simulations show that Δ L increases by the radius of the ice floe and for sizes larger than 6 km (500-1000 m cloud altitude) asymptotically reaches maximum values, which corresponds to an infinite straight ice edge. Furthermore, the impact of these 3-D-radiative effects on retrieval of cloud optical properties was investigated. The enhanced brightness of a dark pixel next to an ice edge results in uncertainties of up to 90 and 30% in retrievals of cloud optical thickness and effective radius reff, respectively. With help of Δ L quantified here, an

  15. Laser-induced activation of regeneration processes in spine disc cartilage

    Science.gov (United States)

    Sobol, Emil N.; Vorobjeva, Natalia N.; Sviridov, Alexander P.; Omelchenko, Alexander I.; Baskov, Andrey V.; Shekhter, Anatoliy B.; Baskov, Vladimir A.; Feldchtein, Felix I.; Kamensky, Vladislav A.; Kuranov, Roman V.

    2000-05-01

    The effect of laser radiation on the regeneration processes in spine disk cartilage has been studied in-vivo. We used rabbits as a model and a Holmium (2.09 micrometer) and an Erbium fiber (1.56 micrometer) lasers for irradiation the discs which were preliminary opened to remove annulus fibrosus and the nucleus pulposus of the intervertebral disc. The irradiated zone has been examined using an optical coherent tomography in one month after the operation and conventional histological technique in two months after the laser operation. It has been shown that laser radiation promotes the growth of the new cartilaginous tissue of fibrous and hyaline types.

  16. Computerized three-dimensional treatment planning system utilizing interactive colour graphics

    Energy Technology Data Exchange (ETDEWEB)

    McShan, D L; Silverman, A; Lanza, D M; Reinstein, L E; Glicksman, A S [Rhode Island Hospital (US). Dept. of Radiation Oncology

    1979-06-01

    A new computerized radiation treatment planning system has been developed to aid in three-dimensional treatment planning. Using interactive colour graphics in conjunction with a PDP 11/45 computer, the system can take multiple transverse contours and construct a perspective display of the treatment region showing organ surfaces as well as cross-sectional contours. With interactively selected orientations, the display allows easy perception of the relative positioning of the treatment volume and the neighbouring anatomy. For external beam treatment planning, interactive computer simulation is used to select diaphragm sizes which best conform to the target area while avoiding sensitive structures. Dose calculations for the selected beams are carried out on multiple transverse planes. The calculational planes and surfaces are displayed in perspective with radiation dosage displayed in an interactively manipulated colour display. Altogether the system provides an easy assessment of the volume to be irradiated, interactive selection of optimal arrangements of treatment fields and a means of visualizing and evaluating the resulting dose distributions.

  17. Metrical analysis of disc-condyle relation with different splint treatment positions in patients with TMJ disc displacement

    Directory of Open Access Journals (Sweden)

    Mu-Qing Liu

    Full Text Available Abstract Objective: To evaluate the effect of bite positions characterizing different splint treatments (anterior repositioning and stabilization splints on the disc-condyle relation in patients with TMJ disc displacement with reduction (DDwR, using magnetic resonance imaging (MRI. Material and Methods: 37 patients, with a mean age of 18.8±4.3 years (7 male and 30 females and diagnosed with DDwR based on the RDC/TMD, were recruited. MRI metrical analysis of the spatial changes of the disc/condyle, as well as their relationships, was done in three positions: maximum intercuspation (Position 1, anterior repositioning splint position (Position 2, and stabilization splint position (Position 3. Disc/condyle coordinate measurements and disc condyle angles were determined and compared. Results: In Position 1, the average disc-condyle angle was 53.4° in the 60 joints with DDwR, while it was −13.3° with Position 2 and 30.1° with Position 3. The frequency of successful "disc recapture" with Position 2 was significantly higher (58/60, 96.7% than Position 3 (20/60, 33.3%. In Positions 2 and 3, the condyle moved forward and downward while the disc moved backward. The movements were, however, more remarkable with Position 2. Conclusions: Anterior repositioning of the mandible improves the spatial relationship between the disc and condyle in patients with DDwR. In addition to anterior and inferior movement of the condyle, transitory posterior movement of the disc also occurred.

  18. Depth-enhanced three-dimensional-two-dimensional convertible display based on modified integral imaging.

    Science.gov (United States)

    Park, Jae-Hyeung; Kim, Hak-Rin; Kim, Yunhee; Kim, Joohwan; Hong, Jisoo; Lee, Sin-Doo; Lee, Byoungho

    2004-12-01

    A depth-enhanced three-dimensional-two-dimensional convertible display that uses a polymer-dispersed liquid crystal based on the principle of integral imaging is proposed. In the proposed method, a lens array is located behind a transmission-type display panel to form an array of point-light sources, and a polymer-dispersed liquid crystal is electrically controlled to pass or to scatter light coming from these point-light sources. Therefore, three-dimensional-two-dimensional conversion is accomplished electrically without any mechanical movement. Moreover, the nonimaging structure of the proposed method increases the expressible depth range considerably. We explain the method of operation and present experimental results.

  19. An algorithm for three-dimensional imaging in the positron camera

    International Nuclear Information System (INIS)

    Chen Kun; Ma Mei; Xu Rongfen; Shen Miaohe

    1986-01-01

    A mathematical algorithm of back-projection filtered for image reconstructions using two-dimensional signals detected from parallel multiwire proportional chambers is described. The approaches of pseudo three-dimensional and full three-dimensional image reconstructions are introduced, and the available point response functions are defined as well. The designing parameters and computation procedure of the full three-dimensional method is presented

  20. Two- and three-dimensional CT analysis of ankle fractures

    International Nuclear Information System (INIS)

    Magid, D.; Fishman, E.K.; Ney, D.R.; Kuhlman, J.E.

    1988-01-01

    CT with coronal and sagittal reformatting (two-dimensional CT) and animated volumetric image rendering (three-dimensional CT) was used to assess ankle fractures. Partial volume limits transaxial CT in assessments of horizontally oriented structures. Two-dimensional CT, being orthogonal to the plafond, superior mortise, talar dome, and tibial epiphysis, often provides the most clinically useful images. Two-dimensional CT is most useful in characterizing potentially confusing fractures, such as Tillaux (anterior tubercle), triplane, osteochondral talar dome, or nondisplaced talar neck fractures, and it is the best study to confirm intraarticular fragments. Two-and three-dimensional CT best indicate the percentage of articular surface involvement and best demonstrate postoperative results or complications (hardware migration, residual step-off, delayed union, DJD, AVN, etc). Animated three-dimensional images are the preferred means of integrating the two-dimensional findings for surgical planning, as these images more closely simulate the clinical problem

  1. Evaluation of three-dimensional virtual perception of garments

    Science.gov (United States)

    Aydoğdu, G.; Yeşilpinar, S.; Erdem, D.

    2017-10-01

    In recent years, three-dimensional design, dressing and simulation programs came into prominence in the textile industry. By these programs, the need to produce clothing samples for every design in design process has been eliminated. Clothing fit, design, pattern, fabric and accessory details and fabric drape features can be evaluated easily. Also, body size of virtual mannequin can be adjusted so more realistic simulations can be created. Moreover, three-dimensional virtual garment images created by these programs can be used while presenting the product to end-user instead of two-dimensional photograph images. In this study, a survey was carried out to investigate the visual perception of consumers. The survey was conducted for three different garment types, separately. Questions about gender, profession etc. was asked to the participants and expected them to compare real samples and artworks or three-dimensional virtual images of garments. When survey results were analyzed statistically, it is seen that demographic situation of participants does not affect visual perception and three-dimensional virtual garment images reflect the real sample characteristics better than artworks for each garment type. Also, it is reported that there is no perception difference depending on garment type between t-shirt, sweatshirt and tracksuit bottom.

  2. Apparent quasar disc sizes in the "bird's nest" paradigm

    Science.gov (United States)

    Abolmasov, P.

    2017-04-01

    Context. Quasar microlensing effects make it possible to measure the accretion disc sizes around distant supermassive black holes that are still well beyond the spatial resolution of contemporary instrumentation. The sizes measured with this technique appear inconsistent with the standard accretion disc model. Not only are the measured accretion disc sizes larger, but their dependence on wavelength is in most cases completely different from the predictions of the standard model. Aims: We suggest that these discrepancies may arise not from non-standard accretion disc structure or systematic errors, as it was proposed before, but rather from scattering and reprocession of the radiation of the disc. In particular, the matter falling from the gaseous torus and presumably feeding the accretion disc may at certain distances become ionized and produce an extended halo that is free from colour gradients. Methods: A simple analytical model is proposed assuming that a geometrically thick translucent inflow acts as a scattering mirror changing the apparent spatial properties of the disc. This inflow may be also identified with the broad line region or its inner parts. Results: Such a model is able to explain the basic properties of the apparent disc sizes, primarily their large values and their shallow dependence on wavelength. The only condition required is to scatter a significant portion of the luminosity of the disc. This can easily be fulfilled if the scattering inflow has a large geometrical thickness and clumpy structure.

  3. High energy gain in three-dimensional simulations of light sail acceleration

    Energy Technology Data Exchange (ETDEWEB)

    Sgattoni, A., E-mail: andrea.sgattoni@polimi.it [Dipartimento di Energia, Politecnico di Milano, Milano (Italy); CNR, Istituto Nazionale di Ottica, u.o.s. “Adriano Gozzini,” Pisa (Italy); Sinigardi, S. [CNR, Istituto Nazionale di Ottica, u.o.s. “Adriano Gozzini,” Pisa (Italy); Dipartimento di Fisica e Astronomia, Università di Bologna, Bologna (Italy); INFN sezione di Bologna, Bologna (Italy); Macchi, A. [CNR, Istituto Nazionale di Ottica, u.o.s. “Adriano Gozzini,” Pisa (Italy); Dipartimento di Fisica “Enrico Fermi,” Università di Pisa, Pisa (Italy)

    2014-08-25

    The dynamics of radiation pressure acceleration in the relativistic light sail regime are analysed by means of large scale, three-dimensional (3D) particle-in-cell simulations. Differently to other mechanisms, the 3D dynamics leads to faster and higher energy gain than in 1D or 2D geometry. This effect is caused by the local decrease of the target density due to transverse expansion leading to a “lighter sail.” However, the rarefaction of the target leads to an earlier transition to transparency limiting the energy gain. A transverse instability leads to a structured and inhomogeneous ion distribution.

  4. High energy gain in three-dimensional simulations of light sail acceleration

    International Nuclear Information System (INIS)

    Sgattoni, A.; Sinigardi, S.; Macchi, A.

    2014-01-01

    The dynamics of radiation pressure acceleration in the relativistic light sail regime are analysed by means of large scale, three-dimensional (3D) particle-in-cell simulations. Differently to other mechanisms, the 3D dynamics leads to faster and higher energy gain than in 1D or 2D geometry. This effect is caused by the local decrease of the target density due to transverse expansion leading to a “lighter sail.” However, the rarefaction of the target leads to an earlier transition to transparency limiting the energy gain. A transverse instability leads to a structured and inhomogeneous ion distribution.

  5. Three-dimensional labeling program for elucidation of the geometric properties of biological particles in three-dimensional space.

    Science.gov (United States)

    Nomura, A; Yamazaki, Y; Tsuji, T; Kawasaki, Y; Tanaka, S

    1996-09-15

    For all biological particles such as cells or cellular organelles, there are three-dimensional coordinates representing the centroid or center of gravity. These coordinates and other numerical parameters such as volume, fluorescence intensity, surface area, and shape are referred to in this paper as geometric properties, which may provide critical information for the clarification of in situ mechanisms of molecular and cellular functions in living organisms. We have established a method for the elucidation of these properties, designated the three-dimensional labeling program (3DLP). Algorithms of 3DLP are so simple that this method can be carried out through the use of software combinations in image analysis on a personal computer. To evaluate 3DLP, it was applied to a 32-cell-stage sea urchin embryo, double stained with FITC for cellular protein of blastomeres and propidium iodide for nuclear DNA. A stack of optical serial section images was obtained by confocal laser scanning microscopy. The method was found effective for determining geometric properties and should prove applicable to the study of many different kinds of biological particles in three-dimensional space.

  6. Research on shape parameters of circular arc disc teeth for three-cone bit

    Directory of Open Access Journals (Sweden)

    Qin Hu

    2018-03-01

    Full Text Available Through the single row drilling experiment, this paper studied the regularity of the tooth shape parameter's influence to the disc teeth's rock-breaking effect, which provided some basis for the composite teeth type roller bit's combined experimental study and the structure design of the tooth type. This experimental research is only for the circular arc disc teeth which is arranged on the composite teeth type roller bit's main tooth. The experiments were designed using the method of orthogonal design and the results were analyzed by the fuzzy optimization method. The results show that the disc tooth's drilling effect is the best when the tip diameter is 2 mm, taper angle is 30° and the groove number is 8, and the disc tooth's drilling effect is the second best when the tip diameter is 3 mm, taper angle is 30° and the groove number is 7. The above two combined ways of drilling effect's difference is very small (the difference of the degree of the membership is 0.003.

  7. Analysis and validation of carbohydrate three-dimensional structures

    International Nuclear Information System (INIS)

    Lütteke, Thomas

    2009-01-01

    The article summarizes the information that is gained from and the errors that are found in carbohydrate structures in the Protein Data Bank. Validation tools that can locate these errors are described. Knowledge of the three-dimensional structures of the carbohydrate molecules is indispensable for a full understanding of the molecular processes in which carbohydrates are involved, such as protein glycosylation or protein–carbohydrate interactions. The Protein Data Bank (PDB) is a valuable resource for three-dimensional structural information on glycoproteins and protein–carbohydrate complexes. Unfortunately, many carbohydrate moieties in the PDB contain inconsistencies or errors. This article gives an overview of the information that can be obtained from individual PDB entries and from statistical analyses of sets of three-dimensional structures, of typical problems that arise during the analysis of carbohydrate three-dimensional structures and of the validation tools that are currently available to scientists to evaluate the quality of these structures

  8. Three Dimensional Polarimetric Neutron Tomography of Magnetic Fields

    DEFF Research Database (Denmark)

    Sales, Morten; Strobl, Markus; Shinohara, Takenao

    2018-01-01

    Through the use of Time-of-Flight Three Dimensional Polarimetric Neutron Tomography (ToF 3DPNT) we have for the first time successfully demonstrated a technique capable of measuring and reconstructing three dimensional magnetic field strengths and directions unobtrusively and non-destructively wi......Through the use of Time-of-Flight Three Dimensional Polarimetric Neutron Tomography (ToF 3DPNT) we have for the first time successfully demonstrated a technique capable of measuring and reconstructing three dimensional magnetic field strengths and directions unobtrusively and non...... and reconstructed, thereby providing the proof-of-principle of a technique able to reveal hitherto unobtainable information on the magnetic fields in the bulk of materials and devices, due to a high degree of penetration into many materials, including metals, and the sensitivity of neutron polarisation to magnetic...... fields. The technique puts the potential of the ToF time structure of pulsed neutron sources to full use in order to optimise the recorded information quality and reduce measurement time....

  9. Gas Modelling in the Disc of HD 163296

    Science.gov (United States)

    Tilling, I.; Woitke, P.; Meeus, G.; Mora, A.; Montesinos, B.; Riviere-Marichalar, P.; Eiroa, C.; Thi, W. -F.; Isella, A.; Roberge, A.; hide

    2011-01-01

    We present detailed model fits to observations of the disc around the Herbig Ae star HD 163296. This well-studied object has an age of approx. 4Myr, with evidence of a circumstellar disc extending out to approx. 540AU. We use the radiation thermo-chemical disc code ProDiMo to model the gas and dust in the circumstellar disc of HD 163296, and attempt to determine the disc properties by fitting to observational line and continuum data. These include new Herschel/PACS observations obtained as part of the open-time key program GASPS (Gas in Protoplanetary Systems), consisting of a detection of the [Oi] 63 m line and upper limits for several other far infrared lines. We complement this with continuum data and ground-based observations of the CO-12 3-2, 2-1 and CO-13 J=1-0 line transitions, as well as the H2 S(1) transition. We explore the effects of stellar ultraviolet variability and dust settling on the line emission, and on the derived disc properties. Our fitting efforts lead to derived gas/dust ratios in the range 9-100, depending on the assumptions made. We note that the line fluxes are sensitive in general to the degree of dust settling in the disc, with an increase in line flux for settled models. This is most pronounced in lines which are formed in the warm gas in the inner disc, but the low excitation molecular lines are also affected. This has serious implications for attempts to derive the disc gas mass from line observations. We derive fractional PAH abundances between 0.007 and 0.04 relative to ISM levels. Using a stellar and UV excess input spectrum based on a detailed analysis of observations, we find that the all observations are consistent with the previously assumed disc geometry

  10. Three-dimensional development of tensile pre-strained annulus fibrosus cells for tissue regeneration: An in-vitro study

    Energy Technology Data Exchange (ETDEWEB)

    Chuah, Yon Jin [School of Chemical and Biomedical Engineering, Nanyang Technological University, 62 Nanyang Drive, Singapore 637459 (Singapore); Lee, Wu Chean [University Hospital Conventry & Warwickshire NHS Trust, Clifford Bridge Road, West Midlands CV2, 2DX (United Kingdom); Wong, Hee Kit [Department of Orthopedic Surgery, National University Health System, NUHS Tower Block Level 11, 1E Kent Ridge Road, Singapore 119228 (Singapore); Kang, Yuejun, E-mail: yuejun.kang@ntu.edu.sg [School of Chemical and Biomedical Engineering, Nanyang Technological University, 62 Nanyang Drive, Singapore 637459 (Singapore); Hee, Hwan Tak, E-mail: HTHee@ntu.edu.sg [School of Chemical and Biomedical Engineering, Nanyang Technological University, 62 Nanyang Drive, Singapore 637459 (Singapore); Pinnacle Spine & Scoliosis Centre, 3 Mount Elizabeth, Mount Elizabeth Medical Centre, #04-07, Singapore 228510 (Singapore); School of Physical and Mathematical Sciences, Nanyang Technological University, 21 Nanyang Link, Singapore 637459 (Singapore)

    2015-02-01

    Prior research has investigated the immediate response after application of tensile strain on annulus fibrosus (AF) cells for the past decade. Although mechanical strain can produce either catabolic or anabolic consequences to the cell monolayer, little is known on how to translate these findings into further tissue engineering applications. Till to date, the application and effect of tensile pre-strained cells to construct a three-dimensional (3D) AF tissue remains unknown. This study aims to investigate the effect of tensile pre-strained exposure of 1 to 24 h on the development of AF pellet culture for 3 weeks. Equibiaxial cyclic tensile strain was applied on AF monolayer cells over a period of 24 h, which was subsequently developed into a cell pellet. Investigation on cellular proliferation, phenotypic gene expression, and histological changes revealed that tensile pre-strain for 24 h had significant and lasting effect on the AF tissue development, with enhanced cell proliferation, and up-regulation of collagen type I, II, and aggrecan expression. Our results demonstrated the regenerative ability of AF cell pellets subjected to 24 h tensile pre-straining. Knowledge on the effects of tensile pre-strain exposure is necessary to optimize AF development for tissue reconstruction. Moreover, the tensile pre-strained cells may further be utilized in either cell therapy to treat mild disc degeneration disease, or the development of a disc construct for total disc replacement. - Highlights: • Establishment of tensile pre-strained cell line population for annulus development. • Tensile strain limits collagen gene expression declination in monolayer culture. • Tensile pre-strained cells up-regulate their matrix protein in 3D pellet culture.

  11. Semi-analog Monte Carlo (SMC) method for time-dependent non-linear three-dimensional heterogeneous radiative transfer problems

    International Nuclear Information System (INIS)

    Yun, Sung Hwan

    2004-02-01

    Radiative transfer is a complex phenomenon in which radiation field interacts with material. This thermal radiative transfer phenomenon is composed of two equations which are the balance equation of photons and the material energy balance equation. The two equations involve non-linearity due to the temperature and that makes the radiative transfer equation more difficult to solve. During the last several years, there have been many efforts to solve the non-linear radiative transfer problems by Monte Carlo method. Among them, it is known that Semi-Analog Monte Carlo (SMC) method developed by Ahrens and Larsen is accurate regard-less of the time step size in low temperature region. But their works are limited to one-dimensional, low temperature problems. In this thesis, we suggest some method to remove their limitations in the SMC method and apply to the more realistic problems. An initially cold problem was solved over entire temperature region by using piecewise linear interpolation of the heat capacity, while heat capacity is still fitted as a cubic curve within the lowest temperature region. If we assume the heat capacity to be linear in each temperature region, the non-linearity still remains in the radiative transfer equations. We then introduce the first-order Taylor expansion to linearize the non-linear radiative transfer equations. During the linearization procedure, absorption-reemission phenomena may be described by a conventional reemission time sampling scheme which is similar to the repetitive sampling scheme in particle transport Monte Carlo method. But this scheme causes significant stochastic errors, which necessitates many histories. Thus, we present a new reemission time sampling scheme which reduces stochastic errors by storing the information of absorption times. The results of the comparison of the two schemes show that the new scheme has less stochastic errors. Therefore, the improved SMC method is able to solve more realistic problems with

  12. Application of three-dimensional CT reconstruction cranioplasty

    International Nuclear Information System (INIS)

    Yan Shuli; Yun Yongxing; Wan Kunming; Qiu Jian

    2011-01-01

    Objective: To study the application of three-dimensional CT reconstruction in cranioplasty. Methods: 46 patients with skull defect were divided into two group. One group underwent CT examination and three-dimensional reconstruction, and then the Titanium nets production company manufactured corresponding titanium meshes were shaped those data before the operation. The other group received traditional operation in which titanium meshes were shaped during operation. The average time of operation were compared. Results: The average time of operation of the first group is 86.6±13.6 mins, and that of the second group is 115±15.0 mins. The difference of average operation time between the two groups was statistically significant. Conclusion: Three-dimensional CT reconstruction techniques contribute to shorten the average operation time, reduce the intensity of neurosurgeon's work and the patien's risk. (authors)

  13. Computational methods for three-dimensional microscopy reconstruction

    CERN Document Server

    Frank, Joachim

    2014-01-01

    Approaches to the recovery of three-dimensional information on a biological object, which are often formulated or implemented initially in an intuitive way, are concisely described here based on physical models of the object and the image-formation process. Both three-dimensional electron microscopy and X-ray tomography can be captured in the same mathematical framework, leading to closely-related computational approaches, but the methodologies differ in detail and hence pose different challenges. The editors of this volume, Gabor T. Herman and Joachim Frank, are experts in the respective methodologies and present research at the forefront of biological imaging and structural biology.   Computational Methods for Three-Dimensional Microscopy Reconstruction will serve as a useful resource for scholars interested in the development of computational methods for structural biology and cell biology, particularly in the area of 3D imaging and modeling.

  14. Three-dimensional tokamak equilibria and stellarators with two-dimensional magnetic symmetry

    International Nuclear Information System (INIS)

    Garabedian, P.R.

    1997-01-01

    Three-dimensional computer codes have been developed to simulate equilibrium, stability and transport in tokamaks and stellarators. Bifurcated solutions of the tokamak problem suggest that three-dimensional effects may be more important than has generally been thought. Extensive calculations have led to the discovery of a stellarator configuration with just two field periods and with aspect ratio 3.2 that has a magnetic field spectrum B mn with toroidal symmetry. Numerical studies of equilibrium, stability and transport for this new device, called the Modular Helias-like Heliac 2 (MHH2), will be presented. (author)

  15. Evaluation of diagnostic quality in musculoskeletal three-dimensional CT scans

    International Nuclear Information System (INIS)

    Vannier, M.W.; Hildebolt, C.F.; Gilula, L.A.; Sutherland, C.J.; Offutt, C.J.; Drebin, R.; Mantle, M.; Giordono, T.A.

    1988-01-01

    A major application of three-dimensional computed tomography (CT) is in the imaging of the skeleton. Three-dimensional CT has an important role in determining the presence and extent of congenital and acquired orthopedic abnormalities. The objective of this study was to compare the diagnostic sensitivity and specificity of three-dimensional CT, planar CT, and plain radiography in the detection and characterization of orthopedic abnormalities. Three-dimensional CT scan reconstructions were obtained by two methods, surface reconstruction and volumetric techniques. Seventy patients were imaged with CT, three-dimensional CT, and plain radiography. The consensus opinion of experts with access to all images plus clinical history, surgical findings, and follow-up findings were taken as truth. Expert radiologists read these cases in a blinded fashion. The results were compared using receiver operating characteristic (ROC) analysis. The diagnostic value of each three-dimensional reconstruction method and the parameters used to perform the reconstructions were evaluated

  16. Hawking radiation of a high-dimensional rotating black hole

    Energy Technology Data Exchange (ETDEWEB)

    Zhao, Ren; Zhang, Lichun; Li, Huaifan; Wu, Yueqin [Shanxi Datong University, Institute of Theoretical Physics, Department of Physics, Datong (China)

    2010-01-15

    We extend the classical Damour-Ruffini method and discuss Hawking radiation spectrum of high-dimensional rotating black hole using Tortoise coordinate transformation defined by taking the reaction of the radiation to the spacetime into consideration. Under the condition that the energy and angular momentum are conservative, taking self-gravitation action into account, we derive Hawking radiation spectrums which satisfy unitary principle in quantum mechanics. It is shown that the process that the black hole radiates particles with energy {omega} is a continuous tunneling process. We provide a theoretical basis for further studying the physical mechanism of black-hole radiation. (orig.)

  17. Three-dimensional absorbed dose determinations by N.M.R. analysis of phantom-dosemeters

    International Nuclear Information System (INIS)

    Gambarini, G.; Birattari, C.; Fumagalli, M.L.; Vai, A.; Monti, D.; Salvadori, P.; Facchielli, L.; Sichirollo, A.E.

    1996-01-01

    Magnetic resonance imaging of a tissue-equivalent phantom is a promising technique for three-dimensional determination of absorbed dose from ionizing radiation. A reliable method of determining the spatial distribution of absorbed dose is indispensable for the planning of treatment in the presently developed radiotherapy techniques aimed at obtaining high energy selectively delivered to cancerous tissues, with low dose delivered to the surrounding healthy tissue. Aqueous gels infused with the Fricke dosemeter (i.e. with a ferrous sulphate solution), as proposed in 1984 by Gore et al., have shown interesting characteristics and, in spite of some drawbacks that cause a few limitations to their utilisation, they have shown the feasibility of three-dimensional dose determinations by nuclear magnetic resonance (NMR) imaging. Fricke-infused agarose gels with various compositions have been analysed, considering the requirements of the new radiotherapy techniques, in particular Boron Neutron Capture Therapy (B.N.C.T.) and proton therapy. Special attention was paid to obtain good tissue equivalence for every radiation type of interest. In particular, the tissue equivalence for thermal neutrons, which is a not simple problem, has also been satisfactorily attained. The responses of gel-dosemeters having the various chosen compositions have been analysed, by mean of NMR instrumentation. Spectrophotometric measurements have also been performed, to verify the consistence of the results. (author)

  18. Three-dimensional echocardiography of normal and pathologic mitral valve: a comparison with two-dimensional transesophageal echocardiography

    NARCIS (Netherlands)

    Salustri, A.; Becker, A. E.; van Herwerden, L.; Vletter, W. B.; ten Cate, F. J.; Roelandt, J. R.

    1996-01-01

    This study was done to ascertain whether three-dimensional echocardiography can facilitate the diagnosis of mitral valve abnormalities. The value of the additional information provided by three-dimensional echocardiography compared with two-dimensional multiplane transesophageal echocardiography for

  19. Three-Dimensional Numerical Evaluation of Thermal Performance of Uninsulated Wall Assemblies: Preprint

    Energy Technology Data Exchange (ETDEWEB)

    Ridouane, E. H.; Bianchi, M.

    2011-11-01

    This study describes a detailed three-dimensional computational fluid dynamics modeling to evaluate the thermal performance of uninsulated wall assemblies accounting for conduction through framing, convection, and radiation. The model allows for material properties variations with temperature. Parameters that were varied in the study include ambient outdoor temperature and cavity surface emissivity. Understanding the thermal performance of uninsulated wall cavities is essential for accurate prediction of energy use in residential buildings. The results can serve as input for building energy simulation tools for modeling the temperature dependent energy performance of homes with uninsulated walls.

  20. Formation of three-dimensional images using selectograms and diffraction gratings

    International Nuclear Information System (INIS)

    Ganzherli, N.M.; Denisyuk, Yu. N.

    1995-01-01

    The results of experiments on recording referenceless selectograms reconstructing three-dimensional images are reported. Selectograms were formed by separating the radiation of an object into two components using diffraction gratings placed in front of a photosensitive layer. They were recorded on thin-layer inclined light-sensitive plates using pseudodeep holograms. The possibilities of recording referenceless selectograms by coherent radiation and radiation with disturbed spatial coherence are studied. In the case of recording a selectogram by coherent radiation, the radiation scattered by an object was separated into two components by means of a diffraction grating placed in front of an inclined photosensitive plate. Selectograms recorded in such a way reconstructed volume images of objects with resolution sufficient for visual perception. For recording by incoherent radiation, an interferometer was proposed that consisted of two diffraction gratings and translated the plane of zero phase difference of interfering beams to the center of an inclined plate. Coherence of a beam illuminating an object was disturbed by moving a diffuser illuminating an object transparency. A selectogram recorded in such a way reconstructed an image in the form of a narrow horizontal luminous strip corresponding to one of horizontal cross sections of the object being recorded. An experiment on multiple recording selectograms on a single plate using a sequential shift of the interferometer alone the optical axis of the system was performed. In this case, the reconstructed image represented a system of horizontal luminous strips, each representing one of the lines of the image of the object being recorded. 8 refs., 3 figs

  1. Method for the determination of the three-dimensional structure of ultrashort relativistic electron bunches

    Energy Technology Data Exchange (ETDEWEB)

    Geloni, Gianluca; Ilinski, Petr; Saldin, Evgeni; Schneidmiller, Evgeni; Yurkov, Mikhail

    2009-05-15

    We describe a novel technique to characterize ultrashort electron bunches in Xray Free-Electron Lasers. Namely, we propose to use coherent Optical Transition Radiation to measure three-dimensional (3D) electron density distributions. Our method relies on the combination of two known diagnostics setups, an Optical Replica Synthesizer (ORS) and an Optical Transition Radiation (OTR) imager. Electron bunches are modulated at optical wavelengths in the ORS setup.When these electron bunches pass through a metal foil target, coherent radiation pulses of tens MW power are generated. It is thereafter possible to exploit advantages of coherent imaging techniques, such as direct imaging, diffractive imaging, Fourier holography and their combinations. The proposed method opens up the possibility of real-time, wavelength-limited, single-shot 3D imaging of an ultrashort electron bunch. (orig.)

  2. Stellar photospheric abundances as a probe of discs and planets

    Science.gov (United States)

    Jermyn, Adam S.; Kama, Mihkel

    2018-06-01

    Protoplanetary discs, debris discs, and disrupted or evaporating planets can all feed accretion on to stars. The photospheric abundances of such stars may then reveal the composition of the accreted material. This is especially likely in B to mid-F type stars, which have radiative envelopes and hence less bulk-photosphere mixing. We present a theoretical framework (CAM), considering diffusion, rotation, and other stellar mixing mechanisms to describe how the accreted material interacts with the bulk of the star. This allows the abundance pattern of the circumstellar material to be calculated from measured stellar abundances and parameters (vrot, Teff). We discuss the λ Boötis phenomenon and the application of CAM on stars hosting protoplanetary discs (HD 100546, HD 163296), debris discs (HD 141569, HD 21997), and evaporating planets (HD 195689/KELT-9).

  3. Study of the nonlinear three-dimensional Debye screening in plasmas

    International Nuclear Information System (INIS)

    Lin Chang; Zhao Jinbao; Zhang Xiulian

    2000-01-01

    The nonlinear three-dimensional Debye screening in plasmas is investigated. New analytical solutions for the three-dimensional Poisson equation have been obtained for the nonlinear Debye potential for the first time. We derive exact analytical expression for the special case of the nonlinear three-dimensional Debye screening in plasmas. (orig.)

  4. Airborne observations and simulations of three-dimensional radiative interactions between Arctic boundary layer clouds and ice floes

    Directory of Open Access Journals (Sweden)

    M. Schäfer

    2015-07-01

    Full Text Available Based on airborne spectral imaging observations, three-dimensional (3-D radiative effects between Arctic boundary layer clouds and highly variable Arctic surfaces were identified and quantified. A method is presented to discriminate between sea ice and open water under cloudy conditions based on airborne nadir reflectivity γλ measurements in the visible spectral range. In cloudy cases the transition of γλ from open water to sea ice is not instantaneous but horizontally smoothed. In general, clouds reduce γλ above bright surfaces in the vicinity of open water, while γλ above open sea is enhanced. With the help of observations and 3-D radiative transfer simulations, this effect was quantified to range between 0 and 2200 m distance to the sea ice edge (for a dark-ocean albedo of αwater = 0.042 and a sea-ice albedo of αice = 0.91 at 645 nm wavelength. The affected distance Δ L was found to depend on both cloud and sea ice properties. For a low-level cloud at 0–200 m altitude, as observed during the Arctic field campaign VERtical Distribution of Ice in Arctic clouds (VERDI in 2012, an increase in the cloud optical thickness τ from 1 to 10 leads to a decrease in Δ L from 600 to 250 m. An increase in the cloud base altitude or cloud geometrical thickness results in an increase in Δ L; for τ = 1/10 Δ L = 2200 m/1250 m in case of a cloud at 500–1000 m altitude. To quantify the effect for different shapes and sizes of ice floes, radiative transfer simulations were performed with various albedo fields (infinitely long straight ice edge, circular ice floes, squares, realistic ice floe field. The simulations show that Δ L increases with increasing radius of the ice floe and reaches maximum values for ice floes with radii larger than 6 km (500–1000 m cloud altitude, which matches the results found for an infinitely long, straight ice edge. Furthermore, the influence of these 3-D radiative effects on the retrieved cloud optical

  5. Airborne observations and simulations of three-dimensional radiative interactions between Arctic boundary layer clouds and ice floes

    Science.gov (United States)

    Schäfer, M.; Bierwirth, E.; Ehrlich, A.; Jäkel, E.; Wendisch, M.

    2015-07-01

    Based on airborne spectral imaging observations, three-dimensional (3-D) radiative effects between Arctic boundary layer clouds and highly variable Arctic surfaces were identified and quantified. A method is presented to discriminate between sea ice and open water under cloudy conditions based on airborne nadir reflectivity γλ measurements in the visible spectral range. In cloudy cases the transition of γλ from open water to sea ice is not instantaneous but horizontally smoothed. In general, clouds reduce γλ above bright surfaces in the vicinity of open water, while γλ above open sea is enhanced. With the help of observations and 3-D radiative transfer simulations, this effect was quantified to range between 0 and 2200 m distance to the sea ice edge (for a dark-ocean albedo of αwater = 0.042 and a sea-ice albedo of αice = 0.91 at 645 nm wavelength). The affected distance Δ L was found to depend on both cloud and sea ice properties. For a low-level cloud at 0-200 m altitude, as observed during the Arctic field campaign VERtical Distribution of Ice in Arctic clouds (VERDI) in 2012, an increase in the cloud optical thickness τ from 1 to 10 leads to a decrease in Δ L from 600 to 250 m. An increase in the cloud base altitude or cloud geometrical thickness results in an increase in Δ L; for τ = 1/10 Δ L = 2200 m/1250 m in case of a cloud at 500-1000 m altitude. To quantify the effect for different shapes and sizes of ice floes, radiative transfer simulations were performed with various albedo fields (infinitely long straight ice edge, circular ice floes, squares, realistic ice floe field). The simulations show that Δ L increases with increasing radius of the ice floe and reaches maximum values for ice floes with radii larger than 6 km (500-1000 m cloud altitude), which matches the results found for an infinitely long, straight ice edge. Furthermore, the influence of these 3-D radiative effects on the retrieved cloud optical properties was investigated

  6. RADIATIVE AND MOMENTUM-BASED MECHANICAL ACTIVE GALACTIC NUCLEUS FEEDBACK IN A THREE-DIMENSIONAL GALAXY EVOLUTION CODE

    International Nuclear Information System (INIS)

    Choi, Ena; Ostriker, Jeremiah P.; Naab, Thorsten; Johansson, Peter H.

    2012-01-01

    We study the growth of black holes (BHs) in galaxies using three-dimensional smoothed particle hydrodynamic simulations with new implementations of the momentum mechanical feedback, and restriction of accreted elements to those that are gravitationally bound to the BH. We also include the feedback from the X-ray radiation emitted by the BH, which heats the surrounding gas in the host galaxies, and adds radial momentum to the fluid. We perform simulations of isolated galaxies and merging galaxies and test various feedback models with the new treatment of the Bondi radius criterion. We find that overall the BH growth is similar to what has been obtained by earlier works using the Springel, Di Matteo, and Hernquist algorithms. However, the outflowing wind velocities and mechanical energy emitted by winds are considerably higher (v w ∼ 1000-3000 km s –1 ) compared to the standard thermal feedback model (v w ∼ 50-100 km s –1 ). While the thermal feedback model emits only 0.1% of BH released energy in winds, the momentum feedback model emits more than 30% of the total energy released by the BH in winds. In the momentum feedback model, the degree of fluctuation in both radiant and wind output is considerably larger than in standard treatments. We check that the new model of BH mass accretion agrees with analytic results for the standard Bondi problem.

  7. Heat engine in the three-dimensional spacetime

    Energy Technology Data Exchange (ETDEWEB)

    Mo, Jie-Xiong [Institute of Theoretical Physics, Lingnan Normal University,Zhanjiang, 524048, Guangdong (China); Department of Physics, Lingnan Normal University,Zhanjiang, 524048, Guangdong (China); Liang, Feng [Department of Physics, Lingnan Normal University,Zhanjiang, 524048, Guangdong (China); Li, Gu-Qiang [Institute of Theoretical Physics, Lingnan Normal University,Zhanjiang, 524048, Guangdong (China); Department of Physics, Lingnan Normal University,Zhanjiang, 524048, Guangdong (China)

    2017-03-02

    We define a kind of heat engine via three-dimensional charged BTZ black holes. This case is quite subtle and needs to be more careful. The heat flow along the isochores does not equal to zero since the specific heat C{sub V}≠0 and this point completely differs from the cases discussed before whose isochores and adiabats are identical. So one cannot simply apply the paradigm in the former literatures. However, if one introduces a new thermodynamic parameter associated with the renormalization length scale, the above problem can be solved. We obtain the analytical efficiency expression of the three-dimensional charged BTZ black hole heat engine for two different schemes. Moreover, we double check with the exact formula. Our result presents the first specific example for the sound correctness of the exact efficiency formula. We argue that the three-dimensional charged BTZ black hole can be viewed as a toy model for further investigation of holographic heat engine. Furthermore, we compare our result with that of the Carnot cycle and extend the former result to three-dimensional spacetime. In this sense, the result in this paper would be complementary to those obtained in four-dimensional spacetime or ever higher. Last but not the least, the heat engine efficiency discussed in this paper may serve as a criterion to discriminate the two thermodynamic approaches introduced in ref. https://www.doi.org/10.1103/PhysRevD.92.124069 and our result seems to support the approach which introduces a new thermodynamic parameter R=r{sub 0}.

  8. The role of three dimensional functional lung imaging in radiation treatment planning: the functional dose-volume histogram

    International Nuclear Information System (INIS)

    Marks, Lawrence B.; Spencer, David P.; Sherouse, George W.; Bentel, Gunilla; Clough, Robert; Vann, Karen; Jaszczak, Ronald; Coleman, R. Edward; Prosnitz, Leonard R.

    1995-01-01

    tumor improved in several patients. In four patients who achieved a complete response scored by CT with chemotherapy prior to XRT, persistent hypoperfusion was present at and adjacent to the tumor site in three. Among 30 patients with cancers not arising in the lung (14 breast, 12 lymphoma, 4 others), perfusion defects were seen in only 4 (2 adjacent and 2 apart). Recognition of decreases in perfusion mainly impacted on treatment planning for a few patients with poor pulmonary function and limited target volumes. DV F Hs have been useful in beam selection for patients with marked perfusion heterogeneities. Conclusions: Lung perfusion scans provide functional information not provided by CT scans that can be useful in designing radiation treatment beams that minimize incidental irradiation of the functional regions of the lung. This approach appears to be most helpful in patients with gross intrathoracic lung cancer, especially those with small targets and relatively poor pulmonary function. One limitation of this approach is that some of the defects adjacent to the tumor site reperfuse following treatment, indicating that these scans identify perfusion rather than potential perfusion. Three dimensional functional data can be used to generate DV F Hs that may be more predictive of the physiological consequences of the radiation than conventional DVHs. Additional work is currently underway to test this hypothesis

  9. Subjective figure reversal in two- and three-dimensional perceptual space.

    Science.gov (United States)

    Radilová, J; Radil-Weiss, T

    1984-08-01

    A permanently illuminated pattern of Mach's truncated pyramid can be perceived according to the experimental instruction given, either as a three-dimensional reversible figure with spontaneously changing convex and concave interpretation (in one experiment), or as a two-dimensional reversible figure-ground pattern (in another experiment). The reversal rate was about twice as slow, without the subjects being aware of it, if it was perceived as a three-dimensional figure compared to the situation when it was perceived as two-dimensional. It may be hypothetized that in the three-dimensional case, the process of perception requires more sequential steps than in the two-dimensional one.

  10. Three-Dimensional Reconstruction of Sandpile Interiors

    Science.gov (United States)

    Seidler, G. T.

    2001-03-01

    The granular bed, or sandpile, has become one of the condensed matter physicist's favorite systems. In addition to conceptual appeal, the simplest sandpile of monodisperse hard spheres is a valuable model system for understanding powders, liquids, and metallic glasses. Any fundamental approach to the transport and mechanical properties of three-dimensional mesoscale disordered materials must follow from a thorough understanding of their structure. However, in the overwhelming majority of cases, structure measurements have been limited to the mean filling fraction and the structural autocorrelation function. This is particularly unfortunate in the ongoing sandpile renaissance, where some of the most interesting questions concern structure and the relationship between structure and dynamics. I will discuss the combination of synchrotron x-ray microtomography and computer vision algorithms to perform three-dimensional virtual reconstructions of real sandpiles. This technique is rapid and noninvasive, and is applicable to samples large enough to separate bulk and boundary properties. The resulting complete knowledge of structure can be used to calculate otherwise inaccessible correlation functions. I will present results for several measures of the bond-orientational order in three-dimensional sandpiles, including fabric tensors and nematic order parameters.

  11. A plastic surgery application in evolution: three-dimensional printing.

    Science.gov (United States)

    Gerstle, Theodore L; Ibrahim, Ahmed M S; Kim, Peter S; Lee, Bernard T; Lin, Samuel J

    2014-02-01

    Three-dimensional printing represents an evolving technology still in its infancy. Currently, individuals and small business entities have the ability to manufacture physical objects from digital renderings, computer-aided design, and open source files. Design modifications and improvements in extrusion methods have made this technology much more affordable. This article explores the potential uses of three-dimensional printing in plastic surgery. A review was performed detailing the known uses of three-dimensional printing in medicine. The potential applications of three-dimensional printing in plastic surgery are discussed. Various applications for three-dimensional printing technology have emerged in medicine, including printing organs, printing body parts, bio-printing, and computer-aided tissue engineering. In plastic surgery, these tools offer various prospective applications for surgical planning, resident education, and the development of custom prosthetics. Numerous applications exist in medicine, including the printing of devices, implants, tissue replacements, and even whole organs. Plastic surgeons may likely find this technology indispensable in surgical planning, education, and prosthetic device design and development in the near future.

  12. Three-dimensional (3D) analysis of the temporomandibular joint

    DEFF Research Database (Denmark)

    Kitai, N.; Kreiborg, S.; Murakami, S.

    Symposium Orthodontics 2001: Where are We Now? Where are We Going?, three-dimensional analysis, temporomandibular joint......Symposium Orthodontics 2001: Where are We Now? Where are We Going?, three-dimensional analysis, temporomandibular joint...

  13. Study on three dimensional seismic isolation system

    International Nuclear Information System (INIS)

    Morishita, Masaki; Kitamura, Seiji

    2003-01-01

    Japan Nuclear Cycle Development Institute (JNC) and Japan Atomic Power Company (JAPC) launched joint research programs on structural design and three-dimensional seismic isolation technologies, as part of the supporting R and D activities for the feasibility studies on commercialized fast breeder reactor cycle systems. A research project by JAPC under the auspices of the Ministry of Economy, Trade, and Industry (METI) with technical support by JNC is included in this joint study. This report contains the results of the research on the three-dimensional seismic isolation technologies, and the results of this year's study are summarized in the following five aspects. (1) Study on Earthquake Condition for Developing 3-dimensional Base Isolation System. The case study S2 is one of the maximum ground motions, of which the records were investigated up to this time. But a few observed near the fault exceed the case study S2 in the long period domain, depending on the fault length and conditions. Generally it is appropriate that the response spectra ratio (vertical/horizontal) is 0.6. (2) Performance Requirement for 3-dimensional Base Isolation System and Devices. Although the integrity map of main equipment/piping dominate the design criteria for the 3-dimensional base isolation system, the combined integrity map is the same as those of FY 2000, which are under fv=1Hz and over hv=20%. (3) Developing Targets and Schedule for 3-dimensional Isolation Technology. The target items for 3-dimensional base isolation system were rearranged into a table, and developing items to be examined concerning the device were also adjusted. A development plan until FY 2009 was made from the viewpoint of realization and establishment of a design guideline on 3-dimensional base isolation system. (4) Study on 3-dimensional Entire Building Base Isolation System. Three ideas among six ideas that had been proposed in FY2001, i.e., '3-dimensional base isolation system incorporating hydraulic

  14. Compact binary merger and kilonova: outflows from remnant disc

    Science.gov (United States)

    Yi, Tuan; Gu, Wei-Min; Liu, Tong; Kumar, Rajiv; Mu, Hui-Jun; Song, Cui-Ying

    2018-05-01

    Outflows launched from a remnant disc of compact binary merger may have essential contribution to the kilonova emission. Numerical calculations are conducted in this work to study the structure of accretion flows and outflows. By the incorporation of limited-energy advection in the hyper-accretion discs, outflows occur naturally from accretion flows due to imbalance between the viscous heating and the sum of the advective and radiative cooling. Following this spirit, we revisit the properties of the merger outflow ejecta. Our results show that around 10-3 ˜ 10-1 M⊙ of the disc mass can be launched as powerful outflows. The amount of unbound mass varies with the disc mass and the viscosity. The outflow-contributed peak luminosity is around 1040 ˜ 1041 erg s-1. Such a scenario can account for the observed kilonovae associated with short gamma-ray bursts, including the recent event AT2017gfo (GW170817).

  15. FluorWPS: A Monte Carlo ray-tracing model to compute sun-induced chlorophyll fluorescence of three-dimensional canopy

    Science.gov (United States)

    A model to simulate radiative transfer (RT) of sun-induced chlorophyll fluorescence (SIF) of three-dimensional (3-D) canopy, FluorWPS, was proposed and evaluated. The inclusion of fluorescence excitation was implemented with the ‘weight reduction’ and ‘photon spread’ concepts based on Monte Carlo ra...

  16. Three dimensional analysis of laterally loaded piles

    International Nuclear Information System (INIS)

    Yilmaz, C.

    1987-01-01

    In this study static analysis of laterally loaded pile is studied by the three models. The first model is the beam on discrete elastic springs. This model is analyzed using a flexibility method. The second model is the beam on a two-parameter elastic foundation. This model is analyzed using the linear finite element method. The third model is the finite element model, using the three-dimensional iso-parametric parabolic brick element. Three-dimensional pile group analysis is also performed using elastic constants of single pile obtained by any one of the above analyses. The main objective is to develop computer programs for each model related to single piles and to group analysis. Then, the deflections, rotations, moments, shears, stresses and strains of the single pile are obtained at any arbitrary point. Comparison is made between each model and with other studies such as Poulos 1971, Desai and Appel 1976. In addition, to provide a benchmark of three-dimensional finite element analysis, the Boussinesq problem is analyzed. (orig.)

  17. Two-dimensional radiation shielding optimization analysis of spent fuel transport container

    International Nuclear Information System (INIS)

    Tian Yingnan; Chen Yixue; Yang Shouhai

    2013-01-01

    The intelligent radiation shielding optimization design software platform is a one-dimensional multi-target radiation shielding optimization program which is developed on the basis of the genetic algorithm program and one-dimensional discrete ordinate program-ANISN. This program was applied in the optimization design analysis of the spent fuel transport container radiation shielding. The multi-objective optimization calculation model of the spent fuel transport container radiation shielding was established, and the optimization calculation of the spent fuel transport container weight and radiation dose rate was carried by this program. The calculation results were checked by Monte-Carlo program-MCNP/4C. The results show that the weight of the optimized spent fuel transport container decreases to 81.1% of the origin and the radiation dose rate decreases to below 65.4% of the origin. The maximum deviation between the calculated values from the program and the MCNP is below 5%. The results show that the optimization design scheme is feasible and the calculation result is correct. (authors)

  18. Three-dimensional attached viscous flow basic principles and theoretical foundations

    CERN Document Server

    Hirschel, Ernst Heinrich; Kordulla, Wilhelm

    2014-01-01

    Viscous flow is usually treated in the frame of boundary-layer theory and as a two-dimensional flow. At best, books on boundary layers provide the describing equations for three-dimensional boundary layers, and solutions only for certain special cases.   This book presents the basic principles and theoretical foundations of three-dimensional attached viscous flows as they apply to aircraft of all kinds. Though the primary flight speed range is that of civil air transport vehicles, flows past other flying vehicles up to hypersonic speeds are also considered. Emphasis is put on general three-dimensional attached viscous flows and not on three-dimensional boundary layers, as this wider scope is necessary in view of the theoretical and practical problems that have to be overcome in practice.   The specific topics covered include weak, strong, and global interaction; the locality principle; properties of three-dimensional viscous flows; thermal surface effects; characteristic properties; wall compatibility con...

  19. Estimate of the damage in organs induced by neutrons in three-dimensional conformal radiotherapy

    International Nuclear Information System (INIS)

    Benites R, J. L.; Vega C, H. R.; Uribe, M. del R.

    2014-08-01

    By means of Monte Carlo methods was considered the damage in the organs, induced by neutrons, of patients with cancer that receive treatment in modality of three-dimensional conformal radiotherapy (3D-CRT) with lineal accelerator Varian Ix. The objective of this work was to estimate the damage probability in radiotherapy patients, starting from the effective dose by neutrons in the organs and tissues out of the treatment region. For that a three-dimensional mannequin of equivalent tissue of 30 x 100 x 30 cm 3 was modeled and spherical cells were distributed to estimate the Kerma in equivalent tissue and the absorbed dose by neutrons. With the absorbed dose the effective dose was calculated using the weighting factors for the organ type and radiation type. With the effective dose and the damage factors, considered in the ICRP 103, was considered the probability of damage induction in organs. (Author)

  20. Non-dosimetric quality assurance for the three-dimensional radiation treatment planning systems using a multi-leaf collimator phantom

    International Nuclear Information System (INIS)

    Tateoka, Kunihiko; Nagase, Daiki; Sato, Takahito; Shimizume, Kazunari; Ouchi, Atsushi; Nakata, Kensei; Hareyama, Masato

    2008-01-01

    Evaluation of errors and limitations in simulation software for three-dimensional radiation treatment systems (3D-RTPS) is an important issue. Non-dosimetric quality assurance (QA) of the simulation software of 3D-RTPS was evaluated by graphical displays of JAW and multi-leaf collimator (MLC) settings in a 3D-RTPS. The influence of observations made using the phantom depends on human errors and several parameters of the CT scan set, such as slice thickness and spacing, pixel size, partial volume effects and the reconstructed image orientation. We explored the methods that were minimally influenced by these errors and parameters. The QA phantom (MLC phantom) has been designed for checking a JAW and MLC settings in a 3D-RTPS is used for non-dosimetric QA. We analyzed the CT value of the boundary the structures of the MLC phantom. The relative CT value for thickness 1 mm slice in border of each structure body of MLC phantom respectively shows a decrease of about 2%, 4%, 10% by 2 mm, 3 mm and 5 mm. In case of thickness 5 mm slice, the mean deference of border of virtual radiation beams and phantom was 0.8 mm, and standard deviation of them was 0.6 mm. And the mean difference of border of a DRR image and phantom was 0.08 mm and the standard deviation of them 0.6 mm. In case of thickness 2 mm slice, the mean deference of border of virtual radiation beams and phantom was -0.18 mm, and standard deviation of them was 0.32 mm. And the mean difference of border of a DRR image and phantom was 0.87 mm and the standard deviation of them 0.54 mm. The result of the study is useful for improvement in a precision of non-dosimetric QA. Our method of non-dosimetric QA can minimize human error and influence of several parameters of the CT scan set. The MLC phantom is a useful tool in the QA of radiation therapy with application to 3D-RTPS, CT simulators, and virtual simulation packages with MLC display capabilities. (author)

  1. Upregulated epidermal growth factor receptor expression following near-infrared irradiation simulating solar radiation in a three-dimensional reconstructed human corneal epithelial tissue culture model

    Directory of Open Access Journals (Sweden)

    Tanaka Y

    2016-08-01

    Full Text Available Yohei Tanaka,1,2 Jun Nakayama2 1Department of Plastic Surgery, Clinica Tanaka Plastic, Reconstructive Surgery and Anti-aging Center, 2Department of Molecular Pathology, Shinshu University Graduate School of Medicine, Matsumoto, Nagano, Japan Background and objective: Humans are increasingly exposed to near-infrared (NIR radiation from both natural (eg, solar and artificial (eg, electrical appliances sources. Although the biological effects of sun and ultraviolet (UV exposure have been extensively investigated, the biological effect of NIR radiation is still unclear. We previously reported that NIR as well as UV induces photoaging and standard UV-blocking materials, such as sunglasses, do not sufficiently block NIR. The objective of this study was to investigate changes in gene expression in three-dimensional reconstructed corneal epithelial tissue culture exposed to broad-spectrum NIR irradiation to simulate solar NIR radiation that reaches human tissues.Materials and methods: DNA microarray and quantitative real-time polymerase chain reaction analysis were used to assess gene expression levels in a three-dimensional reconstructed corneal epithelial model composed of normal human corneal epithelial cells exposed to water-filtered broad-spectrum NIR irradiation with a contact cooling (20°C. The water-filter allowed 1,000–1,800 nm wavelengths and excluded 1,400–1,500 nm wavelengths.Results: A DNA microarray with >62,000 different probes showed 25 and 150 genes that were up- or downregulated by at least fourfold and twofold, respectively, after NIR irradiation. In particular, epidermal growth factor receptor (EGFR was upregulated by 19.4-fold relative to control cells. Quantitative real-time polymerase chain reaction analysis revealed that two variants of EGFR in human corneal epithelial tissue were also significantly upregulated after five rounds of 10 J/cm2 irradiation (P<0.05.Conclusion: We found that NIR irradiation induced the

  2. Static and dynamic properties of three-dimensional dot-type magnonic crystals

    International Nuclear Information System (INIS)

    Maksymov, Artur; Spinu, Leonard

    2016-01-01

    The static and dynamic magnetization of three-dimensional magnonic metamaterials has been investigated. By numerical means it was analyzed the impact of space dimensionality on the properties of magnonic crystal with unit cell consisting of four dots. It is find out the possibility of multi-vortex core formation which is related to the increasing of the crystal height by three-dimensional periodicity of single crystal layer. Additionally is provided the analysis of ferromagnetic resonance phenomenon for two-dimensional and three-dimensional structures. For the unsaturated magnetization of three-dimensional crystal the several pronounced resonance frequencies were detected.

  3. Static and dynamic properties of three-dimensional dot-type magnonic crystals

    Energy Technology Data Exchange (ETDEWEB)

    Maksymov, Artur, E-mail: maxyartur@gmail.com [Advanced Materials Research Institute, University of New Orleans, LA 70148 (United States); Department of General Physics, Chernivtsi National University, Chernivtsi 58012 (Ukraine); Spinu, Leonard [Advanced Materials Research Institute, University of New Orleans, LA 70148 (United States); Department of Physics, University of New Orleans, New Orleans, LA 70148 (United States)

    2016-04-01

    The static and dynamic magnetization of three-dimensional magnonic metamaterials has been investigated. By numerical means it was analyzed the impact of space dimensionality on the properties of magnonic crystal with unit cell consisting of four dots. It is find out the possibility of multi-vortex core formation which is related to the increasing of the crystal height by three-dimensional periodicity of single crystal layer. Additionally is provided the analysis of ferromagnetic resonance phenomenon for two-dimensional and three-dimensional structures. For the unsaturated magnetization of three-dimensional crystal the several pronounced resonance frequencies were detected.

  4. Three-Dimensional Flows

    CERN Document Server

    Araujo, Vitor; Viana, Marcelo

    2010-01-01

    In this book, the authors present the elements of a general theory for flows on three-dimensional compact boundaryless manifolds, encompassing flows with equilibria accumulated by regular orbits. The book aims to provide a global perspective of this theory and make it easier for the reader to digest the growing literature on this subject. This is not the first book on the subject of dynamical systems, but there are distinct aspects which together make this book unique. Firstly, this book treats mostly continuous time dynamical systems, instead of its discrete counterpart, exhaustively treated

  5. Three-dimensional structure of a swarm of the salp Thalia democratica within a cold-core eddy off southeast Australia

    Science.gov (United States)

    Everett, J. D.; Baird, M. E.; Suthers, I. M.

    2011-12-01

    Swarms of the salp Thalia democratica periodically occur off southeast Australia following the austral spring bloom of phytoplankton. In October 2008 a filament of upwelled water was advected south by the adjacent East Australian Current and formed a 30 km diameter cold-core eddy (CCE). The three-dimensional structure of a subsurface swarm of T. democratica within the eddy was examined using both oblique and vertical hauls and an optical plankton counter (OPC) deployed on a towed body. The CCE displayed distinct uplift of the nutricline and elevated fluorescence. Net samples show the zooplankton community was dominated by T. democratica, comprising 73%-88% of zooplankton abundance. The size distribution of T. democratica measured from net samples was 0.5-5 mm and was used to interpret the OPC transects, which showed the swarm formed a 15 km diameter disc located 20-40 m deep in the center of the eddy. The maximum salp abundance was in the pycnocline and coincided with the subsurface fluorescence maximum. The mean abundance of T. democratica size particles within the disc was 5003 individuals m-3 (ind. m-3), contrasted with only 604 ind. m-3 at the outer edge of the eddy. The vertically concentrated and horizontally constrained disc-shaped salp swarm occurred at the interface of salp-bearing inner shelf water and nutrient-rich upwelled water in a CCE. The physical processes that formed the CCE on the inshore edge of the western boundary current led to the largest density of salps recorded.

  6. Three-diemensional materials science: An intersection of three-dimensional reconstructions and simulations

    DEFF Research Database (Denmark)

    Thornton, Katsuyo; Poulsen, Henning Friis

    2008-01-01

    The recent development of experimental techniques that rapidly reconstruct the three-dimensional microstructures of solids has given rise to new possibilities for developing a deeper understanding of the evolution of microstructures and the effects of microstructures on materials properties. Comb...... an overview of this emerging field of materials science, as well as brief descriptions of selected methods and their applicability.......The recent development of experimental techniques that rapidly reconstruct the three-dimensional microstructures of solids has given rise to new possibilities for developing a deeper understanding of the evolution of microstructures and the effects of microstructures on materials properties....... Combined with three-dimensional (3D) simulations and analyses that are capable of handling the complexity of these microstructures, 3D reconstruction, or tomography, has become a powerful tool that provides clear insights into materials processing and properties. This introductory article provides...

  7. New method for solving three-dimensional Schroedinger equation

    International Nuclear Information System (INIS)

    Melezhik, V.S.

    1990-01-01

    The method derived recently for solving a multidimensional scattering problem is applied to a three-dimensional Schroedinger equation. As compared with direct three-dimensional calculations of finite elements and finite differences, this approach gives sufficiently accurate upper and lower approximations to the helium-atom binding energy, which demonstrates its efficiency. 15 refs.; 1 fig.; 2 tabs

  8. Custom-tailored tissue engineered polycaprolactone scaffolds for total disc replacement

    International Nuclear Information System (INIS)

    Van Uden, S; Silva-Correia, J; Correlo, V M; Oliveira, J M; Reis, R L

    2015-01-01

    Degeneration of the intervertebral disc (IVD) represents a significant musculoskeletal disease burden. Tissue engineering has proposed several strategies comprising the use of biodegradable materials to prepare scaffolds that can present mechanical properties similar to those of native IVD tissues. However, this might be insufficient, since the patient’s intervertebral space geometry must be replicated to allow for appropriate implant fixation and integration. Herein, we propose the use of reverse engineering and rapid prototyping techniques with the goal of preparing custom-tailored annulus fibrosus scaffolds; these techniques have previously been applied to rabbit models. The IVD reverse-engineered architecture was obtained by means of microcomputed tomography acquisition and three-dimensional modelling, resulting in a computer-aided design (CAD) that replicates the original rabbit IVD. Later, a fused deposition-modelling three-dimensional printer was used to produce the scaffolds with different geometries provided by the CAD, using polycaprolactone (PCL) with 100% infill density. The microstructure of the PCL scaffolds was investigated by scanning electron microscopy (SEM), which allowed us to observe an adequate fusion adhesion between the layers. The SEM images revealed that, up to the point of moderate resolution, the porosities manually designed in the CAD model were successfully replicated. The PCL scaffolds’ three-dimensional architecture was also assessed by means of microcomputed tomography analysis. Compressive stiffness was determined using a mechanical testing system. Results showed higher values than those of human IVDs (5.9–6.7 kN mm −1 versus 1.2 kN mm −1 , respectively). In vitro studies were performed to investigate the possible cytotoxicity of the polycaprolactone scaffolds’ leachables. The results showed that the custom-tailored PCL scaffolds do not have any deleterious cytotoxic effect over annulus fibrosus cells or the mouse lung

  9. Resonance fluorescence based two- and three-dimensional atom localization

    Science.gov (United States)

    Wahab, Abdul; Rahmatullah; Qamar, Sajid

    2016-06-01

    Two- and three-dimensional atom localization in a two-level atom-field system via resonance fluorescence is suggested. For the two-dimensional localization, the atom interacts with two orthogonal standing-wave fields, whereas for the three-dimensional atom localization, the atom interacts with three orthogonal standing-wave fields. The effect of the detuning and phase shifts associated with the corresponding standing-wave fields is investigated. A precision enhancement in position measurement of the single atom can be noticed via the control of the detuning and phase shifts.

  10. Be discs in coplanar circular binaries: Phase-locked variations of emission lines

    Science.gov (United States)

    Panoglou, Despina; Faes, Daniel M.; Carciofi, Alex C.; Okazaki, Atsuo T.; Baade, Dietrich; Rivinius, Thomas; Borges Fernandes, Marcelo

    2018-01-01

    In this paper, we present the first results of radiative transfer calculations on decretion discs of binary Be stars. A smoothed particle hydrodynamics code computes the structure of Be discs in coplanar circular binary systems for a range of orbital and disc parameters. The resulting disc configuration consists of two spiral arms, and this can be given as input into a Monte Carlo code, which calculates the radiative transfer along the line of sight for various observational coordinates. Making use of the property of steady disc structure in coplanar circular binaries, observables are computed as functions of the orbital phase. Some orbital-phase series of line profiles are given for selected parameter sets under various viewing angles, to allow comparison with observations. Flat-topped profiles with and without superimposed multiple structures are reproduced, showing, for example, that triple-peaked profiles do not have to be necessarily associated with warped discs and misaligned binaries. It is demonstrated that binary tidal effects give rise to phase-locked variability of the violet-to-red (V/R) ratio of hydrogen emission lines. The V/R ratio exhibits two maxima per cycle; in certain cases those maxima are equal, leading to a clear new V/R cycle every half orbital period. This study opens a way to identifying binaries and to constraining the parameters of binary systems that exhibit phase-locked variations induced by tidal interaction with a companion star.

  11. Interactive three-dimensional visualization and creation of geometries for Monte Carlo calculations

    International Nuclear Information System (INIS)

    Theis, C.; Buchegger, K.H.; Brugger, M.; Forkel-Wirth, D.; Roesler, S.; Vincke, H.

    2006-01-01

    The implementation of three-dimensional geometries for the simulation of radiation transport problems is a very time-consuming task. Each particle transport code supplies its own scripting language and syntax for creating the geometries. All of them are based on the Constructive Solid Geometry scheme requiring textual description. This makes the creation a tedious and error-prone task, which is especially hard to master for novice users. The Monte Carlo code FLUKA comes with built-in support for creating two-dimensional cross-sections through the geometry and FLUKACAD, a custom-built converter to the commercial Computer Aided Design package AutoCAD, exists for 3D visualization. For other codes, like MCNPX, a couple of different tools are available, but they are often specifically tailored to the particle transport code and its approach used for implementing geometries. Complex constructive solid modeling usually requires very fast and expensive special purpose hardware, which is not widely available. In this paper SimpleGeo is presented, which is an implementation of a generic versatile interactive geometry modeler using off-the-shelf hardware. It is running on Windows, with a Linux version currently under preparation. This paper describes its functionality, which allows for rapid interactive visualization as well as generation of three-dimensional geometries, and also discusses critical issues regarding common CAD systems

  12. Three-dimensional imagery by encoding sources of X rays

    International Nuclear Information System (INIS)

    Magnin, Isabelle

    1987-01-01

    This research thesis addresses the theoretical and practical study of X ray coded sources, and thus notably aims at exploring whether it would be possible to transform a standard digital radiography apparatus (as those operated in radiology hospital departments) into a low cost three-dimensional imagery system. The author first recalls the principle of conventional tomography and improvement attempts, and describes imagery techniques based on the use of encoding openings and source encoding. She reports the modelling of an imagery system based on encoded sources of X ray, and addresses the original notion of three-dimensional response for such a system. The author then addresses the reconstruction method by considering the reconstruction of a plane object, of a multi-plane object, and of real three-dimensional object. The frequency properties and the tomographic capacities of various types of source codes are analysed. She describes a prototype tomography apparatus, and presents and discusses three-dimensional actual phantom reconstructions. She finally introduces a new principle of dynamic three-dimensional radiography which implements an acquisition technique by 'gating code'. The acquisition principle should allow the reconstruction of volumes animated by periodic deformations, such as the heart for example [fr

  13. Spectral domain optical coherence tomography morphology in optic disc pit associated maculopathy

    Directory of Open Access Journals (Sweden)

    Janusz Michalewski

    2014-01-01

    Full Text Available Purpose: Our purpose was to study the clinical manifestation and course of optic pit maculopathy using Spectral Domain Optical Coherence Tomography (SD- OCT images. Materials and Methods: We used SD-OCT to examine 20 eyes of 19 patients with a macular detachment in combination with an optic. Results: We observed five different fovea appearances in regard to fluid localization. In five eyes, we recorded changes in the fluid distribution with SD-OCT. In 17/20 eyes, we noted a communication between the perineural and subretinal and/or intraretinal space at the margin of the optic disc. Conclusion: 3-dimensional SD-OCT (3D-SDOCT scans revealed a three-fold connection, between subretinal and intraretinal space, perineural space, and the vitreous cavity. Therefore, we suppose that intraretinal or subretinal fluid in optic pit maculopathy may have both a vitreous and cerebrospinal origin. A membrane, covering the optic nerve was noted in 14 cases. Even if it seems intact in some B-scans, it is not complete in others several micrometers apart. Additionally, we observed fluid accumulation below the margin of the optic disc and hyperreflective porous tissue in the optic disc excavation. Those findings do not influence the course of maculopathy.

  14. Imaging characteristics of noncontained migrating disc fragment and cyst

    International Nuclear Information System (INIS)

    Eerens, I.; Demaerel, P.; Haven, F.; Wilms, G.; Loon, J. van; Calenbergh, F. van

    2001-01-01

    The purpose of this article is to review less common presentations of degenerative disc disease on MR imaging. The images of eight patients were retrospectively analyzed. Six of them had transligamentous (or noncontained) disc herniations, the fragments of which were located in the posterior epidural space in three of them. One patient had a transdural disc fragment and one patient had a disc cyst. The cyst was located in the ventrolateral epidural space. On T2-weighted images, the migrated disc fragment returned a higher signal than the disc of origin in 6 of 7 patients. The disc cyst returned a signal similar to that of cerebrospinal fluid. The MR appearances of disc fragments can be puzzling, particularly if they are located in the posterior epidural space. It is important to recognize the abnormalities in order to differentiate them from less common lesions such as hematoma, abscess and neurinoma. (orig.)

  15. Imaging characteristics of noncontained migrating disc fragment and cyst

    Energy Technology Data Exchange (ETDEWEB)

    Eerens, I.; Demaerel, P.; Haven, F.; Wilms, G. [Dept. of Radiology, University Hospitals, Leuven (Belgium); Loon, J. van; Calenbergh, F. van [Dept. of Neurosurgery, University Hospitals, Leuven (Belgium)

    2001-05-01

    The purpose of this article is to review less common presentations of degenerative disc disease on MR imaging. The images of eight patients were retrospectively analyzed. Six of them had transligamentous (or noncontained) disc herniations, the fragments of which were located in the posterior epidural space in three of them. One patient had a transdural disc fragment and one patient had a disc cyst. The cyst was located in the ventrolateral epidural space. On T2-weighted images, the migrated disc fragment returned a higher signal than the disc of origin in 6 of 7 patients. The disc cyst returned a signal similar to that of cerebrospinal fluid. The MR appearances of disc fragments can be puzzling, particularly if they are located in the posterior epidural space. It is important to recognize the abnormalities in order to differentiate them from less common lesions such as hematoma, abscess and neurinoma. (orig.)

  16. Appearance of Keplerian discs orbiting Kerr superspinars

    Energy Technology Data Exchange (ETDEWEB)

    Stuchlik, Zdenek; Schee, Jan, E-mail: zdenek.stuchlik@fpf.slu.c, E-mail: jan.schee@fpf.slu.c [Institute of Physics, Faculty of Philosophy and Science, Silesian University in Opava, Bezrucovo nam. 13, Opava (Czech Republic)

    2010-11-07

    We study optical phenomena related to the appearance of Keplerian accretion discs orbiting Kerr superspinars predicted by string theory. The superspinar exterior is described by standard Kerr naked singularity geometry breaking the black hole limit on the internal angular momentum (spin). We construct local photon escape cones for a variety of orbiting sources that enable us to determine the superspinars silhouette in the case of distant observers. We show that the superspinar silhouette depends strongly on the assumed edge where the external Kerr spacetime is joined to the internal spacetime governed by string theory and significantly differs from the black hole silhouette. The appearance of the accretion disc is strongly dependent on the value of the superspinar spin in both their shape and frequency shift profile. Apparent extension of the disc grows significantly with the growing spin, while the frequency shift grows with the descending spin. This behaviour differs substantially from the appearance of discs orbiting black holes enabling thus, at least in principle, to distinguish clearly the Kerr superspinars and black holes. In vicinity of a Kerr superspinar the non-escaped photons have to be separated to those captured by the superspinar and those being trapped in its strong gravitational field leading to self-illumination of the disc that could even influence its structure and cause self-reflection effect of radiation of the disc. The amount of trapped photons grows with descending superspinar spin. We thus can expect significant self-illumination effects in the field of Kerr superspinars with near-extreme spin a {approx} 1.

  17. Three-dimensional oscillator and Coulomb systems reduced from Kaehler spaces

    International Nuclear Information System (INIS)

    Nersessian, Armen; Yeranyan, Armen

    2004-01-01

    We define the oscillator and Coulomb systems on four-dimensional spaces with U(2)-invariant Kaehler metric and perform their Hamiltonian reduction to the three-dimensional oscillator and Coulomb systems specified by the presence of Dirac monopoles. We find the Kaehler spaces with conic singularity, where the oscillator and Coulomb systems on three-dimensional sphere and two-sheet hyperboloid originate. Then we construct the superintegrable oscillator system on three-dimensional sphere and hyperboloid, coupled to a monopole, and find their four-dimensional origins. In the latter case the metric of configuration space is a non-Kaehler one. Finally, we extend these results to the family of Kaehler spaces with conic singularities

  18. A method to combine three dimensional dose distributions for external beam and brachytherapy radiation treatments for gynecological neoplasms

    International Nuclear Information System (INIS)

    Narayana, V.; Sahijdak, W.M.; Orton, C.G.

    1997-01-01

    Purpose: Radiation treatment of gynecological neoplasms, such as cervical carcinoma, usually combines external radiation therapy with one or more intracavitary brachytherapy applications. Although the dose from external beam radiation therapy and brachytherapy can be calculated and displayed in 3D individually, the dose distributions are not combined. At most, combined point doses are calculated for select points using various time-dose models. In this study, we present a methodology to combine external beam and brachytherapy treatments for gynecological neoplasms. Material and Methods: Three dimensional bio-effect treatment planning to obtain complication probability has been outlined. CT scans of the patient's pelvis with the gynecological applicator in place are used to outline normal tissue and tumor volumes. 3D external beam and brachytherapy treatment plans are developed separately and an external beam dose matrix and a brachytherapy dose matrix was calculated. The dose in each voxel was assumed to be homogeneous. The physical dose in each voxel of the dose matrix was then converted into extrapolated response dose (ERD) based on the linear quadratic model that accounts for the dose per fraction, number of fractions, dose rate, and complete or incomplete repair of sublethal damage (time between fractions). The net biological dose delivered was obtained by summing the ERD grids from external beam and brachytherapy since there was complete repair of sublethal damage between external beam and brachytherapy treatments. The normal tissue complication probability and tumor control probability were obtained using the biological dose matrix based on the critical element model. Results: The outlined method of combining external beam and brachytherapy treatments was implemented on gynecological treatments using an applicator for brachytherapy treatments. Conclusion: Implementation of the biological dose calculation that combine different modalities is extremely useful

  19. Supersymmetric quantum mechanics in three-dimensional space, 1

    International Nuclear Information System (INIS)

    Ui, Haruo

    1984-01-01

    As a direct generalization of the model of supersymmetric quantum mechanics by Witten, which describes the motion of a spin one-half particle in the one-dimensional space, we construct a model of the supersymmetric quantum mechanics in the three-dimensional space, which describes the motion of a spin one-half particle in central and spin-orbit potentials in the context of the nonrelativistic quantum mechanics. With the simplest choice of the (super) potential, this model is shown to reduce to the model of the harmonic oscillator plus constant spin-orbit potential of unit strength of both positive and negative signs, which was studied in detail in our recent paper in connection with ''accidental degeneracy'' as well as the ''graded groups''. This simplest model is discussed in some detail as an example of the three-dimensional supersymmetric quantum mechanical system, where the supersymmetry is an exact symmetry of the system. More general choice of a polynomial superpotential is also discussed. It is shown that the supersymmetry cannot be spontaneously broken for any polynomial superpotential in our three-dimensional model; this result is contrasted to the corresponding one in the one-dimensional model. (author)

  20. Delay-Line Three-Dimensional Position Sensitive Radiation Detection

    Science.gov (United States)

    Jeong, Manhee

    High-resistivity silicon(Si) in large volumes and with good charge carrier transport properties has been produced and achieved success as a radiation detector material over the past few years due to its relatively low cost as well as the availability of well-established processing technologies. One application of that technology is in the fabrication of various position-sensing topologies from which the incident radiation's direction can be determined. We have succeeded in developing the modeling tools for investigating different position-sensing schemes and used those tools to examine both amplitude-based and time-based methods, an assessment that indicates that fine position-sensing can be achieved with simpler readout designs than are conventionally deployed. This realization can make ubiquitous and inexpensive deployment of special nuclear materials (SNM) detecting technology becomes more feasible because if one can deploy position-sensitive semiconductor detectors with only one or two contacts per side. For this purpose, we have described the delay-line radiation detector and its optimized fabrication. The semiconductor physics were simulated, the results from which guided the fabrication of the guard ring structure and the detector electrode, both of which included metal-field-plates. The measured improvement in the leakage current was confirmed with the fabricated devices, and the structures successfully suppressed soft-breakdown. We also demonstrated that fabricating an asymmetric strip-line structure successfully minimizing the pulse shaping and increases the distance through which one can propagate the information of the deposited charge distribution. With fabricated delay-line detectors we can acquire alpha spectra (Am-241) and gamma spectra (Ba-133, Co-57 and Cd-109). The delay-line detectors can therefore be used to extract the charge information from both ion and gamma-ray interactions. Furthermore, standard charge-sensitive circuits yield high SNR

  1. [Research progress of intervertebral disc endogenous stem cells for intervertebral disc regeneration].

    Science.gov (United States)

    Liang, Hang; Deng, Xiangyu; Shao, Zengwu

    2017-10-01

    To summarize the research progress of intervertebral disc endogenous stem cells for intervertebral disc regeneration and deduce the therapeutic potential of endogenous repair for intervertebral disc degeneration. The original articles about intervertebral disc endogenous stem cells for intervertebral disc regeneration were extensively reviewed; the reparative potential in vivo and the extraction and identification in vitro of intervertebral disc endogenous stem cells were analyzed; the prospect of endogenous stem cells for intervertebral disc regeneration was predicted. Stem cell niche present in the intervertebral discs, from which stem cells migrate to injured tissues and contribute to tissues regeneration under certain specific microenvironment. Moreover, the migration of stem cells is regulated by chemokines system. Tissue specific progenitor cells have been identified and successfully extracted and isolated. The findings provide the basis for biological therapy of intervertebral disc endogenous stem cells. Intervertebral disc endogenous stem cells play a crucial role in intervertebral disc regeneration. Therapeutic strategy of intervertebral disc endogenous stem cells is proven to be a promising biological approach for intervertebral disc regeneration.

  2. Results of three-dimensional conformal radiotherapy and thalidomide for advanced hepatocellular carcinoma

    International Nuclear Information System (INIS)

    Hsu, Wei-Chung; Chung, Na-Na; Wang, Po-Ming; Ying, Kung-Shih; Shin, Jeng-Shiann; Chao, Che-Jen; Lin, Gau-De; Chan, Sue-Ching; Ting, Lai-Lei

    2006-01-01

    The purpose of this study was to evaluate the effectiveness of three-dimensional conformal radiotherapy and thalidomide in the treatment of advanced hepatocellular carcinoma. Between 1999 and 2003, 121 patients (mean age, 54.4±12.4 years; range, 20-81 years) with advanced hepatocellular carcinoma received three-dimensional conformal radiotherapy and thalidomide. Radiation was delivered in 1.5 Gy fractions twice daily for 5 days a week, for a total dose of 45-75 Gy. Mean treatment volume was 429.52±408.50 cm 3 (range, 26.89-2284.82 cm 3 ). Thalidomide was given concomitantly: 200 mg/day in 109 patients, 300 mg/day in 8 patients and 400 mg/day in 4 patients. Treatment responses, survival rates and factors affecting survival were analyzed. Treatment responses were observed in 61% of the patients. Liver cirrhosis (P=0.001) and tumor size (P=0.001) significantly affected the tumor responses. Overall survival at 6, 12 and 24 months was 84.8, 60.0 and 44.6%, respectively. On univariate analysis, liver cirrhosis (P=0.003), Karnofsky performance status (P=0.007), tumor size (P<0.001), portal vein tumor thrombosis (P<0.001) and alpha-fetoprotein level (P=0.003) were shown to significantly affect survival. On multivariate analysis, only thrombosis (P=0.039) and alpha-fetoprotein level (P=0.006) were shown to be factors affecting survival. Three-dimensional conformal radiotherapy with thalidomide seems to be effective in the treatment of advanced hepatocellular carcinoma. (author)

  3. Hawking radiation and propagation of massive charged scalar field on a three-dimensional Gödel black hole

    Science.gov (United States)

    González, P. A.; Övgün, Ali; Saavedra, Joel; Vásquez, Yerko

    2018-06-01

    In this paper we consider the three-dimensional Gödel black hole as a background and we study the vector particle tunneling from this background in order to obtain the Hawking temperature. Then, we study the propagation of a massive charged scalar field and we find the quasinormal modes analytically, which turns out be unstable as a consequence of the existence of closed time-like curves. Also, we consider the flux at the horizon and at infinity, and we compute the reflection and transmission coefficients as well as the absorption cross section. Mainly, we show that massive charged scalar waves can be superradiantly amplified by the three-dimensional Gödel black hole and that the coefficients have an oscillatory behavior. Moreover, the absorption cross section is null at the high frequency limit and for certain values of the frequency.

  4. Three-dimensional theory for light-matter interaction

    DEFF Research Database (Denmark)

    Sørensen, Martin Westring; Sørensen, Anders Søndberg

    2008-01-01

    We present a full quantum mechanical three dimensional theory describing an electromagnetic field interacting with an ensemble of identical atoms. The theory is constructed such that it describes recent experiments on light-matter quantum interfaces, where the quantum fluctuations of light...... to a dressed state picture, where the light modes are solutions to the diffraction problem, and develop a perturbative expansion in the fluctuations. The fluctuations are due to quantum fluctuations as well as the random positions of the atoms. In this perturbative expansion we show how the quantum...... fluctuations are mapped between atoms and light while the random positioning of the atoms give rise to decay due to spontaneous emission. Furthermore we identify limits, where the full three dimensional theory reduce to the one dimensional theory typically used to describe the interaction....

  5. Cervical disc hernia operations through posterior laminoforaminotomy.

    Science.gov (United States)

    Yolas, Coskun; Ozdemir, Nuriye Guzin; Okay, Hilmi Onder; Kanat, Ayhan; Senol, Mehmet; Atci, Ibrahim Burak; Yilmaz, Hakan; Coban, Mustafa Kemal; Yuksel, Mehmet Onur; Kahraman, Umit

    2016-01-01

    The most common used technique for posterolateral cervical disc herniations is anterior approach. However, posterior cervical laminotoforaminomy can provide excellent results in appropriately selected patients with foraminal stenosis in either soft disc prolapse or cervical spondylosis. The purpose of this study was to present the clinical outcomes following posterior laminoforaminotomy in patients with radiculopathy. We retrospectively evaluated 35 patients diagnosed with posterolateral cervical disc herniation and cervical spondylosis with foraminal stenosis causing radiculopathy operated by the posterior cervical keyhole laminoforaminotomy between the years 2010 and 2015. The file records and the radiographic images of the 35 patients were assessed retrospectively. The mean age was 46.4 years (range: 34-66 years). Of the patients, 19 were males and 16 were females. In all of the patients, the neurologic deficit observed was radiculopathy. The posterolaterally localized disc herniations and the osteophytic structures were on the left side in 18 cases and on the right in 17 cases. In 10 of the patients, the disc level was at C5-6, in 18 at C6-7, in 2 at C3-4, in 2 at C4-5, in 1 at C7-T1, in 1 patient at both C5-6 and C6-7, and in 1 at both C4-5 and C5-6. In 14 of these 35 patients, both osteophytic structures and protruded disc herniation were present. Intervertebral foramen stenosis was present in all of the patients with osteophytes. Postoperatively, in 31 patients the complaints were relieved completely and four patients had complaints of neck pain and paresthesia radiating to the arm (the success of operation was 88.5%). On control examinations, there was no finding of instability or cervical kyphosis. Posterior cervical laminoforaminotomy is an alternative appropriate choice in both cervical soft disc herniations and cervical stenosis.

  6. Oxidative stress participates in age-related changes in rat lumbar intervertebral discs.

    Science.gov (United States)

    Hou, Gang; Lu, Huading; Chen, Mingjuan; Yao, Hui; Zhao, Huiqing

    2014-01-01

    Aging is a major factor associated with lumber intervertebral disc degeneration, and oxidative stress is known to play an essential role in the pathogenesis of many age-related diseases. In this study, we investigated oxidative stress in intervertebral discs of Wistar rats in three different age groups: youth, adult, and geriatric. Age-related intervertebral disc changes were examined by histological analysis. In addition, oxidative stress was evaluated by assessing nitric oxide (NO), superoxide dismutase (SOD), malondialdehyde (MDA), and advanced oxidation protein products (AOPPs). Intervertebral disc, but not serum, NO concentrations significantly differed between the three groups. Serum and intervertebral disc SOD activity gradually decreased with age. Furthermore, both serum and intervertebral disc MDA and AOPP levels gradually increased with age. Our studies suggest that oxidative stress is associated with age-related intervertebral disc changes. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  7. Three dimensional contact/impact methodology

    International Nuclear Information System (INIS)

    Kulak, R.F.

    1987-01-01

    The simulation of three-dimensional interface mechanics between reactor components and structures during static contact or dynamic impact is necessary to realistically evaluate their structural integrity to off-normal loads. In our studies of postulated core energy release events, we have found that significant structure-structure interactions occur in some reactor vessel head closure designs and that fluid-structure interactions occur within the reactor vessel. Other examples in which three-dimensional interface mechanics play an important role are: (1) impact response of shipping casks containing spent fuel, (2) whipping pipe impact on reinforced concrete panels or pipe-to-pipe impact after a pipe break, (3) aircraft crash on secondary containment structures, (4) missiles generated by turbine failures or tornados, and (5) drops of heavy components due to lifting accidents. The above is a partial list of reactor safety problems that require adequate treatment of interface mechanics and are discussed in this paper

  8. Results of Three-Dimensional Conformal Radiation Therapy for the Treatment of a Solitary Sternal Relapse of Breast Cancer

    International Nuclear Information System (INIS)

    Kim, Hae Young; Huh, Seung Jae; Park, Won; Choi, Do Ho; Kang, Min Kyu; Yang, Jung Hyun; Nam, Seok Jin; Im, Young Hyuck

    2008-01-01

    To evaluate the response and survival rate after three-dimensional conformal radiation therapy (3D-CRT) of patients with a solitary sternal relapse of breast cancer. Seventeen patients between May 1996 and June 2005 were evaluated with the salvage 3D-CRT treatment of a solitary sternal relapse of breast cancer. The treatment fields included the gross tumor volume with 2 cm margins. The total radiation dose was 35.0 ∼61.5 Gy (biologic effective dose of 43.7 ∼76.9 Gy10 using an α/β ratio of 10 Gy), with a daily dose of 1.8∼3.0 Gy. The tumor response was evaluated by the change in maximum tumor size via follow up CT scans 1∼3 months after the completion of treatment. An objective tumor response was achieved in all patients, with a complete response in 5 patients and a partial response in 12 patients. The 5-year overall survival rate was 51.9% (median survival time: 27 months), and the most important factor affecting overall survival was the disease-free interval (interval from primary surgery of breast cancer to the development of sternal metastasis): The 5-year overall survival rate was 61.8% for patients with a disease-free interval ≥12 months and 0.0% for patients < with disease-free interval <12 months (p=0.03). The response to 3D-CRT was good in patients with solitary sternal relapse of breast cancer. Particularly, patients with long disease-free interval from primary surgery survived significantly longer than patients with short disease-free interval from primary surgery

  9. The use of genetic algorithms to model protoplanetary discs

    Science.gov (United States)

    Hetem, Annibal; Gregorio-Hetem, Jane

    2007-12-01

    The protoplanetary discs of T Tauri and Herbig Ae/Be stars have previously been studied using geometric disc models to fit their spectral energy distribution (SED). The simulations provide a means to reproduce the signatures of various circumstellar structures, which are related to different levels of infrared excess. With the aim of improving our previous model, which assumed a simple flat-disc configuration, we adopt here a reprocessing flared-disc model that assumes hydrostatic, radiative equilibrium. We have developed a method to optimize the parameter estimation based on genetic algorithms (GAs). This paper describes the implementation of the new code, which has been applied to Herbig stars from the Pico dos Dias Survey catalogue, in order to illustrate the quality of the fitting for a variety of SED shapes. The star AB Aur was used as a test of the GA parameter estimation, and demonstrates that the new code reproduces successfully a canonical example of the flared-disc model. The GA method gives a good quality of fit, but the range of input parameters must be chosen with caution, as unrealistic disc parameters can be derived. It is confirmed that the flared-disc model fits the flattened SEDs typical of Herbig stars; however, embedded objects (increasing SED slope) and debris discs (steeply decreasing SED slope) are not well fitted with this configuration. Even considering the limitation of the derived parameters, the automatic process of SED fitting provides an interesting tool for the statistical analysis of the circumstellar luminosity of large samples of young stars.

  10. Time-resolved broadband analysis of slow-light propagation and superluminal transmission of electromagnetic waves in three-dimensional photonic crystals

    NARCIS (Netherlands)

    Gómez Rivas, J.; Farré Benet, A.; Niehusmann, J.; Haring Bolivar, P.; Kurz, H.

    2005-01-01

    A time-resolved analysis of the amplitude and phase of THz pulses propagating through three-dimensional photonic crystals is presented. Single-cycle pulses of THz radiation allow measurements over a wide frequency range, spanning more than an octave below, at and above the bandgap of strongly

  11. Anterolateral Approach for Central Thoracic Disc Prolapse-Surgical Strategies Used to Tackle Differing Operative Findings: 3-Dimensional Operative Video.

    Science.gov (United States)

    Patel, Krunal; Budohoski, Karol P; Kenyon, Olivia R P; Barone, Damiano G; Santarius, Thomas; Kirollos, Ramez W; Mannion, Richard J; Trivedi, Rikin A

    2018-04-02

    Thoracic disc prolapses causing cord compression can be challenging. For compressive central disc protrusions, a posterior approach is not suitable due to an unacceptable level of cord manipulation. An anterolateral transthoracic approach provides direct access to the disc prolapse allowing for decompression without disturbing the spinal cord. In this video, we describe 2 cases of thoracic myelopathy from a compressive central thoracic disc prolapse. In both cases, informed consent was obtained. Despite similar radiological appearances of heavy calcification, intraoperatively significant differences can be encountered. We demonstrate different surgical strategies depending on the consistency of the disc and the adherence to the thecal sac. With adequate exposure and detachment from adjacent vertebral bodies, soft discs can be, in most instances, separated from the theca with minimal cord manipulation. On the other hand, largely calcified discs often present a significantly greater challenge and require thinning the disc capsule before removal. In cases with significant adherence to dura, in order to prevent cord injury or cerebrospinal fluid leak a thinned shell can be left, providing total detachment from adjacent vertebrae can be achieved. Postoperatively, the first patient, with a significantly calcified disc, developed a transient left leg weakness which recovered by 3-month follow-up. This video outlines the anatomical considerations and operative steps for a transthoracic approach to a central disc prolapse, whilst demonstrating that computed tomography appearances are not always indicative of potential operative difficulties.

  12. Three-dimensional friction measurement during hip simulation.

    Directory of Open Access Journals (Sweden)

    Robert Sonntag

    Full Text Available Wear of total hip replacements has been the focus of many studies. However, frictional effects, such as high loading on intramodular connections or the interface to the bone, as well as friction associated squeaking have recently increased interest about the amount of friction that is generated during daily activities. The aim of this study was thus to establish and validate a three-dimensional friction setup under standardized conditions.A standard hip simulator was modified to allow for high precision measurements of small frictional effects in the hip during three-dimensional hip articulation. The setup was verified by an ideal hydrostatic bearing and validated with a static-load physical pendulum and an extension-flexion rotation with a dynamic load profile. Additionally, a pendulum model was proposed for screening measurement of frictional effects based on the damping behavior of the angular oscillation without the need for any force/moment transducer. Finally, three-dimensional friction measurements have been realized for ceramic-on-polyethylene bearings of three different sizes (28, 36 and 40 mm.A precision of less than 0.2 Nm during three-dimensional friction measurements was reported, while increased frictional torque (resultant as well as taper torque was measured for larger head diameters. These effects have been confirmed by simple pendulum tests and the theoretical model. A comparison with current literature about friction measurements is presented.This investigation of friction is able to provide more information about a field that has been dominated by the reduction of wear. It should be considered in future pre-clinical testing protocols given by international organizations of standardization.

  13. High-resolution three-dimensional visualization of the rat spinal cord microvasculature by synchrotron radiation micro-CT

    Energy Technology Data Exchange (ETDEWEB)

    Hu, Jianzhong; Cao, Yong; Wu, Tianding; Li, Dongzhe [Department of Spine Surgery, Xiangya Hospital, Central South University, Changsha 410008 (China); Lu, Hongbin, E-mail: hongbinlu@hotmail.com [Department of Sports Medicine, Research Centre of Sports Medicine, Xiangya Hospital, Central South University, Changsha 410008 (China)

    2014-10-15

    Purpose: Understanding the three-dimensional (3D) morphology of the spinal cord microvasculature has been limited by the lack of an effective high-resolution imaging technique. In this study, synchrotron radiation microcomputed tomography (SRµCT), a novel imaging technique based on absorption imaging, was evaluated with regard to the detection of the 3D morphology of the rat spinal cord microvasculature. Methods: Ten Sprague-Dawley rats were used in this ex vivo study. After contrast agent perfusion, their spinal cords were isolated and scanned using conventional x-rays, conventional micro-CT (CµCT), and SRµCT. Results: Based on contrast agent perfusion, the microvasculature of the rat spinal cord was clearly visualized for the first time ex vivo in 3D by means of SRµCT scanning. Compared to conventional imaging techniques, SRµCT achieved higher resolution 3D vascular imaging, with the smallest vessel that could be distinguished approximately 7.4 μm in diameter. Additionally, a 3D pseudocolored image of the spinal cord microvasculature was generated in a single session of SRµCT imaging, which was conducive to detailed observation of the vessel morphology. Conclusions: The results of this study indicated that SRµCT scanning could provide higher resolution images of the vascular network of the spinal cord. This modality also has the potential to serve as a powerful imaging tool for the investigation of morphology changes in the 3D angioarchitecture of the neurovasculature in preclinical research.

  14. Three-dimensional CT imaging of soft-tissue anatomy

    International Nuclear Information System (INIS)

    Fishman, E.K.; Ney, D.R.; Magid, D.; Kuhlman, J.E.

    1988-01-01

    Three-dimensional display of computed tomographic data has been limited to skeletal structures. This was in part related to the reconstruction algorithm used, which relied on a binary classification scheme. A new algorithm, volumetric rendering with percentage classification, provides the ability to display three-dimensional images of muscle and soft tissue. A review was conducted of images in 35 cases in which muscle and/or soft tissue were part of the clinical problem. In all cases, individual muscle groups could be clearly identified and discriminated. Branching vessels in the range of 2.3 mm could be identified. Similarly, lymph nodes could be clearly defined. High-resolution three-dimensional images were found to be useful both in providing an increased understanding of complex muscle and soft tissue anatomy and in surgical planning

  15. THREE DIMENSIONAL GRAPHICAL REPRESENTATION OF QUALITY

    Directory of Open Access Journals (Sweden)

    Vineet V. Kumar

    2014-03-01

    Full Text Available Quality is an important aspect for every firm in modern era of competition. Every product has tough competition in terms of market reach. The factor, which actually makes any product long run in market, is quality and hence quality is the stepping-stone for success of any firm. For everyone meaning of quality is different. We have seen several economists who have defined quality by considering different factors, but what all of them have common in them is Customer satisfaction. Customer satisfaction is the ultimate result of quality. In three-dimensional graphical representation of quality, optimum quality is obtained by using three-dimensional graph by considering some important factors governing quality of any product, limiting factor, and customer satisfaction.

  16. Accretion disc dynamo activity in local simulations spanning weak-to-strong net vertical magnetic flux regimes

    Science.gov (United States)

    Salvesen, Greg; Simon, Jacob B.; Armitage, Philip J.; Begelman, Mitchell C.

    2016-03-01

    Strongly magnetized accretion discs around black holes have attractive features that may explain enigmatic aspects of X-ray binary behaviour. The structure and evolution of these discs are governed by a dynamo-like mechanism, which channels part of the accretion power liberated by the magnetorotational instability (MRI) into an ordered toroidal magnetic field. To study dynamo activity, we performed three-dimensional, stratified, isothermal, ideal magnetohydrodynamic shearing box simulations. The strength of the self-sustained toroidal magnetic field depends on the net vertical magnetic flux, which we vary across almost the entire range over which the MRI is linearly unstable. We quantify disc structure and dynamo properties as a function of the initial ratio of mid-plane gas pressure to vertical magnetic field pressure, β _0^mid = p_gas / p_B. For 10^5 ≥ β _0^mid ≥ 10 the effective α-viscosity parameter scales as a power law. Dynamo activity persists up to and including β _0^mid = 10^2, at which point the entire vertical column of the disc is magnetic pressure dominated. Still stronger fields result in a highly inhomogeneous disc structure, with large density fluctuations. We show that the turbulent steady state βmid in our simulations is well matched by the analytic model of Begelman et al. describing the creation and buoyant escape of toroidal field, while the vertical structure of the disc can be broadly reproduced using this model. Finally, we discuss the implications of our results for observed properties of X-ray binaries.

  17. Application status of three-dimensional CT reconstruction in hepatobiliary surgery

    Directory of Open Access Journals (Sweden)

    JIANG Chao

    2017-02-01

    Full Text Available With the development of imaging technology, three-dimensional CT reconstruction has been widely used in hepatobiliary surgery. Three-dimensional CT reconstruction can divide and reconstruct two-dimensional images into three-dimensional images and clearly show the location of lesion and its relationship with the intrahepatic bile duct system. It has an important value in the preoperative assessment of liver volume, diagnosis and treatment decision-making process, intraoperative precise operation, and postoperative individualized management, and promotes the constant development of hepatobiliary surgery and minimally invasive technology, and therefore, it holds promise for clinical application.

  18. Utility of three-dimensional method for diagnosing meniscal lesions

    International Nuclear Information System (INIS)

    Ohshima, Suguru; Nomura, Kazutoshi; Hirano, Mako; Hashimoto, Noburo; Fukumoto, Tetsuya; Katahira, Kazuhiro

    1998-01-01

    MRI of the knee is a useful method for diagnosing meniscal tears. Although the spin echo method is usually used for diagnosing meniscal tears, we examined the utility of thin slice scan with the three-dimensional method. We reviewed 70 menisci in which arthroscopic findings were confirmed. In this series, sensitivity was 90.9% for medial meniscal injuries and 68.8% for lateral meniscal injuries. There were 3 meniscal tears in which we could not detect tears on preoperative MRI. We could find tears in two of these cases when re-evaluated using the same MRI. In conclusion, we can get the same diagnostic rate with the three-dimensional method compared with the spin echo method. Scan time of the three-dimensional method is 3 minutes, on the other hand that of spin echo method in 17 minutes. This slice scan with three-dimensional method is useful for screening meniscal injuries before arthroscopy. (author)

  19. Three-dimensional features on oscillating microbubbles streaming flows

    Science.gov (United States)

    Rossi, Massimiliano; Marin, Alvaro G.; Wang, Cheng; Hilgenfeldt, Sascha; Kähler, Christian J.

    2013-11-01

    Ultrasound-driven oscillating micro-bubbles have been used as active actuators in microfluidic devices to perform manifold tasks such as mixing, sorting and manipulation of microparticles. A common configuration consists in side-bubbles, created by trapping air pockets in blind channels perpendicular to the main channel direction. This configuration results in bubbles with a semi-cylindrical shape that creates a streaming flow generally considered quasi two-dimensional. However, recent experiments performed with three-dimensional velocimetry methods have shown how microparticles can present significant three-dimensional trajectories, especially in regions close to the bubble interface. Several reasons will be discussed such as boundary effects of the bottom/top wall, deformation of the bubble interface leading to more complex vibrational modes, or bubble-particle interactions. In the present investigation, precise measurements of particle trajectories close to the bubble interface will be performed by means of 3D Astigmatic Particle Tracking Velocimetry. The results will allow us to characterize quantitatively the three-dimensional features of the streaming flow and to estimate its implications in practical applications as particle trapping, sorting or mixing.

  20. Disruption of circumstellar discs by large-scale stellar magnetic fields

    Science.gov (United States)

    ud-Doula, Asif; Owocki, Stanley P.; Kee, Nathaniel Dylan

    2018-05-01

    Spectropolarimetric surveys reveal that 8-10% of OBA stars harbor large-scale magnetic fields, but thus far no such fields have been detected in any classical Be stars. Motivated by this, we present here MHD simulations for how a pre-existing Keplerian disc - like that inferred to form from decretion of material from rapidly rotating Be stars - can be disrupted by a rotation-aligned stellar dipole field. For characteristic stellar and disc parameters of a near-critically rotating B2e star, we find that a polar surface field strength of just 10 G can significantly disrupt the disc, while a field of 100 G, near the observational upper limit inferred for most Be stars, completely destroys the disc over just a few days. Our parameter study shows that the efficacy of this magnetic disruption of a disc scales with the characteristic plasma beta (defined as the ratio between thermal and magnetic pressure) in the disc, but is surprisingly insensitive to other variations, e.g. in stellar rotation speed, or the mass loss rate of the star's radiatively driven wind. The disc disruption seen here for even a modest field strength suggests that the presumed formation of such Be discs by decretion of material from the star would likely be strongly inhibited by such fields; this provides an attractive explanation for why no large-scale fields are detected from such Be stars.

  1. Comparison of Patient Dose in Two-Dimensional Carotid Arteriography and Three-Dimensional Rotational Angiography

    International Nuclear Information System (INIS)

    Tsapaki, Virginia; Vano, Eliseo; Mavrikou, Irini; Neofotistou, Vassiliki; Gallego, Juan Jose; Fernandez, Jose Miguel; Santos, Ernesto; Mendez, Jose

    2008-01-01

    Background and Purpose. It is known that interventional neuroradiology (IN) involves high radiation dose to both patients and staff even if performed by trained operators using modern fluoroscopic X-ray equipment and dose-reducing technology. Therefore, every new technology or imaging tool introduced, such as three-dimensional rotational angiography (3D RA), should be evaluated in terms of radiation dose. 3D RA requires a series with a large number of images in comparison with 2D angiography and it is sometimes considered a high-dose IN procedure. The literature is scarce on the 3D RA radiation dose and in particular there are no data on carotid arteriography (CA). The aim of this study was to investigate patient dose differences between 2D and 3D CA. Methods. The study included 35 patients undergoing 2D CA in hospital 1 and 25 patients undergoing 3D CA in hospital 2. Patient technical data collection included information on the kerma area product (KAP), fluoroscopy time (T), total number of series (S), and total number of acquired images (F). Results. Median KAP was 112 Gy cm 2 and 41 Gy cm 2 for hospitals 1 and 2, respectively, median T was 8.2 min and 5.1 min, median S was 13 and 4, and median F was 247 and 242. Entrance surface air-kerma rate, as measured in 'medium' fluoroscopy mode measured in 2D acquisition using a 20 cm phantom of polymethylmethacrylate, was 17.3 mGy/min for hospital 1 and 9.2 mGy/min for hospital 2. Conclusion. 3D CA allows a substantial reduction in patient radiation dose compared with 2D CA, while providing the necessary diagnostic information

  2. Integration of Computed Tomography and Three-Dimensional Echocardiography for Hybrid Three-Dimensional Printing in Congenital Heart Disease.

    Science.gov (United States)

    Gosnell, Jordan; Pietila, Todd; Samuel, Bennett P; Kurup, Harikrishnan K N; Haw, Marcus P; Vettukattil, Joseph J

    2016-12-01

    Three-dimensional (3D) printing is an emerging technology aiding diagnostics, education, and interventional, and surgical planning in congenital heart disease (CHD). Three-dimensional printing has been derived from computed tomography, cardiac magnetic resonance, and 3D echocardiography. However, individually the imaging modalities may not provide adequate visualization of complex CHD. The integration of the strengths of two or more imaging modalities has the potential to enhance visualization of cardiac pathomorphology. We describe the feasibility of hybrid 3D printing from two imaging modalities in a patient with congenitally corrected transposition of the great arteries (L-TGA). Hybrid 3D printing may be useful as an additional tool for cardiologists and cardiothoracic surgeons in planning interventions in children and adults with CHD.

  3. Three-dimensional image reconstruction from stereo DSA

    International Nuclear Information System (INIS)

    Sakamoto, Kiyoshi; Kotoura, Noriko; Umehara, Takayoshi; Yamada, Eiji; Inaba, Tomohiro; Itou, Hiroshi

    1999-01-01

    The technique of interventional radiology has spread rapidly in recent years, and three-dimensional information from blood vessel images is being sought to enhance examinations. Stereo digital subtraction angiography (DSA) and rotational DSA were developed for that purpose. However, it is difficult with stereo DSA to observe the image pair during examination and to obtain positional information on blood vessels. Further, the exposure dose is increased in rotational DSA when many mask images need to be collected, and the patient is required to hold his or her breath for a long duration. We therefore devised a technique to construct three-dimensional blood vessel images by employing geometrical information extracted from stereo DSA images using the right and left images. We used a judgment method based on the correlation coefficient, although we had to extract an equal blood vessel from the right and left images to determine the three-dimensional coordinates of the blood vessel. The reconstructed three-dimensional blood vessels were projected from various angles, again by using a virtual focus, and new images were created. These image groups were displayed as rotational images by the animation display function incorporated in the DSA device. This system can observe blood vessel images of the same phase at a free angle, although the image quality is inferior to that of rotational DSA. In addition, because collection of the mask images is reduced, exposure dose can be decreased. Further, the system offers enhanced safety because no mechanical movement of the imaging system is involved. (author)

  4. A DETERMINISTIC METHOD FOR TRANSIENT, THREE-DIMENSIONAL NUETRON TRANSPORT

    International Nuclear Information System (INIS)

    S. GOLUOGLU, C. BENTLEY, R. DEMEGLIO, M. DUNN, K. NORTON, R. PEVEY I.SUSLOV AND H.L. DODDS

    1998-01-01

    A deterministic method for solving the time-dependent, three-dimensional Boltzmam transport equation with explicit representation of delayed neutrons has been developed and evaluated. The methodology used in this study for the time variable of the neutron flux is known as the improved quasi-static (IQS) method. The position, energy, and angle-dependent neutron flux is computed deterministically by using the three-dimensional discrete ordinates code TORT. This paper briefly describes the methodology and selected results. The code developed at the University of Tennessee based on this methodology is called TDTORT. TDTORT can be used to model transients involving voided and/or strongly absorbing regions that require transport theory for accuracy. This code can also be used to model either small high-leakage systems, such as space reactors, or asymmetric control rod movements. TDTORT can model step, ramp, step followed by another step, and step followed by ramp type perturbations. It can also model columnwise rod movement can also be modeled. A special case of columnwise rod movement in a three-dimensional model of a boiling water reactor (BWR) with simple adiabatic feedback is also included. TDTORT is verified through several transient one-dimensional, two-dimensional, and three-dimensional benchmark problems. The results show that the transport methodology and corresponding code developed in this work have sufficient accuracy and speed for computing the dynamic behavior of complex multidimensional neutronic systems

  5. In Vitro Description of Macroscopic Changes of Dental Amalgam Discs Subject to High Temperatures to Forensic Purposes.

    Science.gov (United States)

    Arcos, Carlos; Díaz, Juan-David; Canencio, Kenny; Rodríguez, Diana; Viveros, Carlos; Vega, Jonathan; Lores, Juliana; Sinisterra, Gustavo; Sepúlveda, Wilmer; Moreno, Freddy

    2015-07-01

    To describe the behavior of 45 discs of dental amalgam of known dimension prepared from three commercially available brands of dental amalgam (Contour® Kerr®-USA, Admix® SDI®-Australia and Nu Alloy® Newstethic®-Colombia) when subjected to the action of high temperatures (200 °C, 400 °C, 600 °C, 800 °C, 1000 °C). It was hoped to establish parameters that could be used for human dental identification in cases of charred, burned or incinerated human remains. A pseudo-experimental descriptive in-vitro study was designed to describe the macroscopic physical changes to the surface of 45 discs of pre-prepared amalgam of three commercially available brands exposed to a range of high temperatures. Characteristic and repetitive physical changes were a noticeable feature of the discs of amalgam of each brand of amalgam subjected to the different temperature ranges. These physical changes included changes in dimensional stability, changes in texture, changes in colour, changes in the appearance of fissures and cracks and changes in the fracture and fragmentation of the sample. The characteristics of dental amalgam may be of assistance in cases of human identification where charred, burned or incinerated human remains are a feature and where fingerprints or other soft tissue features are unavailable.

  6. Summary of three-dimensional animation creation based on ethnic culture element

    Directory of Open Access Journals (Sweden)

    Shao Zhaopo

    2016-01-01

    Full Text Available three-dimensional animation is a product combined by technology and art. It is an artistic ex-pression form combining painting, film & television, digital technology, music, and literature. As an audio and visual art, three-dimensional animation has its own unique culture-loading function, technical aesthetic charac-teristics, and requirements for national art expression. This paper aims to find the method to combine digital technology and national art in combination of three-dimensional animation short film creation, and hopes to clear the road for the cultivation of domestic three-dimensional animation quality project.

  7. Measurements of three dimensional residual stress distribution on laser irradiated spot

    International Nuclear Information System (INIS)

    Tanaka, Hirotomo; Akita, Koichi; Ohya, Shin-ichi; Sano, Yuji; Naito, Hideki

    2004-01-01

    Three dimensional residual stress distributions on laser irradiated spots were measured using synchrotron radiation to study the basic mechanism of laser peening. A water-immersed sample of high tensile strength steel was irradiated with Q-switched and frequency-doubled Nd:YAG laser. The residual stress depth profile of the sample was obtained by alternately repeating the measurement and surface layer removal by electrolytic polishing. Tensile residual stresses were observed on the surface of all irradiated spots, whereas residual stress changed to compressive just beneath the surface. The depth of compressive residual stress imparted by laser irradiation and plastic deformation zone increased with increasing the number of laser pulses irradiated on the same spot. (author)

  8. Three-dimensional spiral CT during arterial portography: comparison of three rendering techniques.

    Science.gov (United States)

    Heath, D G; Soyer, P A; Kuszyk, B S; Bliss, D F; Calhoun, P S; Bluemke, D A; Choti, M A; Fishman, E K

    1995-07-01

    The three most common techniques for three-dimensional reconstruction are surface rendering, maximum-intensity projection (MIP), and volume rendering. Surface-rendering algorithms model objects as collections of geometric primitives that are displayed with surface shading. The MIP algorithm renders an image by selecting the voxel with the maximum intensity signal along a line extended from the viewer's eye through the data volume. Volume-rendering algorithms sum the weighted contributions of all voxels along the line. Each technique has advantages and shortcomings that must be considered during selection of one for a specific clinical problem and during interpretation of the resulting images. With surface rendering, sharp-edged, clear three-dimensional reconstruction can be completed on modest computer systems; however, overlapping structures cannot be visualized and artifacts are a problem. MIP is computationally a fast technique, but it does not allow depiction of overlapping structures, and its images are three-dimensionally ambiguous unless depth cues are provided. Both surface rendering and MIP use less than 10% of the image data. In contrast, volume rendering uses nearly all of the data, allows demonstration of overlapping structures, and engenders few artifacts, but it requires substantially more computer power than the other techniques.

  9. Three-dimensional reconstruction of the pigeon inner ear

    NARCIS (Netherlands)

    Hofman, R.; Segenhout, J. M.; Wit, H. P.

    2009-01-01

    Three-dimensional reconstructions of the inner ear of the pigeon (Columba livia domestica), from two-dimensional images, obtained with (conventional) light microscopy or orthogonal-plane fluorescence optical sectioning (OPFOS), are presented. The results are compared with available information on

  10. Clinical evaluation of disc battery ingestion in children.

    Science.gov (United States)

    Mirshemirani, AliReza; Khaleghnejad-Tabari, Ahmad; Kouranloo, Jaefar; Sadeghian, Naser; Rouzrokh, Mohsen; Roshanzamir, Fatolah; Razavi, Sajad; Sayary, Ali Akbar; Imanzadeh, Farid

    2012-04-01

    BACKGROUND The purpose of this study was to evaluate the characteristics, management, and outcomes of disc battery ingestion in children. METHODS We reviewed the medical records of children admitted to Mofid Children's Hospital due to disc battery ingestion from January 2006 to January 2010. Clear history, clinical symptoms and results of imaging studies revealed diagnosis of disc battery ingestion in suspected patients. The clinical data reviewed included age, gender, clinical manifestation, radiologic findings, location of disc battery, duration of ingestion, endoscopic results and surgical treatment. RESULTS We found 22 cases (11 males and 11 females) of disc battery ingestion with a mean age of 4.3 years (range: 9 months to 12 years). Common symptoms were vomiting, cough, dysphagia, and dyspnea. The mean duration of ingestion was 2.7 days (4 hours to 1.5 months). A total of 19 patients had histories of disc battery ingestion, but three cases referred with the above symptoms, and the batteries were accidentally found by x-ray. Only three cases had batteries impacted in the esophagus. Twelve batteries were removed endoscopically, 6 batteries spontaneously passed through the gastrointestinal (GI) tract within 5 to 7 days, and 4 patients underwent surgery due to complications: 3 due to tracheo-esophageal fistula (TEF) and 1 due to intestinal perforation. There was no mortality in our study. CONCLUSION Most cases of disc battery ingestion run uneventful courses, but some may be complicated. If the battery lodges in the esophagus, emergency endoscopic management is necessary. However, once in the stomach, it will usually pass through the GI tract.

  11. Surface representations of two- and three-dimensional fluid flow topology

    Science.gov (United States)

    Helman, James L.; Hesselink, Lambertus

    1990-01-01

    We discuss our work using critical point analysis to generate representations of the vector field topology of numerical flow data sets. Critical points are located and characterized in a two-dimensional domain, which may be either a two-dimensional flow field or the tangential velocity field near a three-dimensional body. Tangent curves are then integrated out along the principal directions of certain classes of critical points. The points and curves are linked to form a skeleton representing the two-dimensional vector field topology. When generated from the tangential velocity field near a body in a three-dimensional flow, the skeleton includes the critical points and curves which provide a basis for analyzing the three-dimensional structure of the flow separation. The points along the separation curves in the skeleton are used to start tangent curve integrations to generate surfaces representing the topology of the associated flow separations.

  12. Three-dimensional magnetophotonic crystals based on artificial opals

    Science.gov (United States)

    Baryshev, A. V.; Kodama, T.; Nishimura, K.; Uchida, H.; Inoue, M.

    2004-06-01

    We fabricated and experimentally investigated three-dimensional magnetophotonic crystals (3D MPCs) based on artificial opals. Opal samples with three-dimensional dielectric lattices were impregnated with different types of magnetic material. Magnetic and structural properties of 3D MPCs were studied by field emission scanning electron microscopy, x-ray diffraction analysis, and vibrating sample magnetometer. We have shown that magnetic materials synthesized in voids of opal lattices and the composites obtained have typical magnetic properties.

  13. Three-dimensional magnetophotonic crystals based on artificial opals

    International Nuclear Information System (INIS)

    Baryshev, A.V.; Kodama, T.; Nishimura, K.; Uchida, H.; Inoue, M.

    2004-01-01

    We fabricated and experimentally investigated three-dimensional magnetophotonic crystals (3D MPCs) based on artificial opals. Opal samples with three-dimensional dielectric lattices were impregnated with different types of magnetic material. Magnetic and structural properties of 3D MPCs were studied by field emission scanning electron microscopy, x-ray diffraction analysis, and vibrating sample magnetometer. We have shown that magnetic materials synthesized in voids of opal lattices and the composites obtained have typical magnetic properties

  14. Magnetohydrodynamic study of three-dimensional instability of the spontaneous fast magnetic reconnection

    International Nuclear Information System (INIS)

    Shimizu, T.; Kondoh, K.; Ugai, M.; Shibata, K.

    2009-01-01

    Three-dimensional instability of the spontaneous fast magnetic reconnection is studied with magnetohydrodynamic (MHD) simulation, where the two-dimensional model of the spontaneous fast magnetic reconnection is destabilized in three dimension. Generally, in two-dimensional magnetic reconnection models, every plasma condition is assumed to be uniform in the sheet current direction. In such two-dimensional MHD simulations, the current sheet destabilized by the initial resistive disturbance can be developed to fast magnetic reconnection by a current driven anomalous resistivity. In this paper, the initial resistive disturbance includes a small amount of fluctuations in the sheet current direction, i.e., along the magnetic neutral line. The other conditions are the same as that of previous two-dimensional MHD studies for fast magnetic reconnection. Accordingly, we may expect that approximately two-dimensional fast magnetic reconnection occurs in the MHD simulation. In fact, the fast magnetic reconnection activated on the first stage of the simulation is two dimensional. However, on the subsequent stages, it spontaneously becomes three dimensional and is strongly localized in the sheet current direction. The resulting three-dimensional fast magnetic reconnection intermittently ejects three-dimensional magnetic loops. Such intermittent ejections of the three-dimensional loops are similar to the intermittent downflows observed in the solar flares. The ejection of the three-dimensional loops seems to be random but, numerically and theoretically, it is shown that the aspect ratio of the ejected loops is limited under a criterion.

  15. Planet-disc interactions with Discontinuous Galerkin Methods using GPUs

    Science.gov (United States)

    Velasco Romero, David A.; Veiga, Maria Han; Teyssier, Romain; Masset, Frédéric S.

    2018-05-01

    We present a two-dimensional Cartesian code based on high order discontinuous Galerkin methods, implemented to run in parallel over multiple GPUs. A simple planet-disc setup is used to compare the behaviour of our code against the behaviour found using the FARGO3D code with a polar mesh. We make use of the time dependence of the torque exerted by the disc on the planet as a mean to quantify the numerical viscosity of the code. We find that the numerical viscosity of the Keplerian flow can be as low as a few 10-8r2Ω, r and Ω being respectively the local orbital radius and frequency, for fifth order schemes and resolution of ˜10-2r. Although for a single disc problem a solution of low numerical viscosity can be obtained at lower computational cost with FARGO3D (which is nearly an order of magnitude faster than a fifth order method), discontinuous Galerkin methods appear promising to obtain solutions of low numerical viscosity in more complex situations where the flow cannot be captured on a polar or spherical mesh concentric with the disc.

  16. MRI definition of target volumes using fuzzy logic method for three-dimensional conformal radiation therapy

    International Nuclear Information System (INIS)

    Caudrelier, Jean-Michel; Vial, Stephane; Gibon, David; Kulik, Carine; Fournier, Charles; Castelain, Bernard; Coche-Dequeant, Bernard; Rousseau, Jean

    2003-01-01

    Purpose: Three-dimensional (3D) volume determination is one of the most important problems in conformal radiation therapy. Techniques of volume determination from tomographic medical imaging are usually based on two-dimensional (2D) contour definition with the result dependent on the segmentation method used, as well as on the user's manual procedure. The goal of this work is to describe and evaluate a new method that reduces the inaccuracies generally observed in the 2D contour definition and 3D volume reconstruction process. Methods and Materials: This new method has been developed by integrating the fuzziness in the 3D volume definition. It first defines semiautomatically a minimal 2D contour on each slice that definitely contains the volume and a maximal 2D contour that definitely does not contain the volume. The fuzziness region in between is processed using possibility functions in possibility theory. A volume of voxels, including the membership degree to the target volume, is then created on each slice axis, taking into account the slice position and slice profile. A resulting fuzzy volume is obtained after data fusion between multiorientation slices. Different studies have been designed to evaluate and compare this new method of target volume reconstruction and a classical reconstruction method. First, target definition accuracy and robustness were studied on phantom targets. Second, intra- and interobserver variations were studied on radiosurgery clinical cases. Results: The absolute volume errors are less than or equal to 1.5% for phantom volumes calculated by the fuzzy logic method, whereas the values obtained with the classical method are much larger than the actual volumes (absolute volume errors up to 72%). With increasing MRI slice thickness (1 mm to 8 mm), the phantom volumes calculated by the classical method are increasing exponentially with a maximum absolute error up to 300%. In contrast, the absolute volume errors are less than 12% for phantom

  17. Possibility of estimating three-dimensional mandibular morphology by cephalogram analysis

    International Nuclear Information System (INIS)

    Kim, S.; Motegi, Etsuko; Kikuchi, Yu; Yamaguchi, Hideharu; Takaki, Takashi; Shibahara, Takahiko

    2007-01-01

    The purpose of this study was to investigate the possibility of a surmise of three-dimensional mandibular morphology by two-dimensional cephalogram analysis. The materials were three-dimensional CT and cephalogram of 20 female mandibular prognathism patients (average age: 25.20±7.49) before there orthognathic surgery. Mandibular bone volume and sponge bone width were calculated from three-dimensional images constructed from CT images using imaging software (Real Intage, KGT inc.). There was a positive correlation (r=0.72) between mandibular volume value and mandibular ramus width. There was a positive correlation between sponge bone width at the site of the mandibular cuspid and mandibular ramus width and SNB angle (r=0.80), and between sponge bone width at the site of the mandibular molar and symphysis height and mandibular ramus width (r=0.81). It was thought that these results will be useful for a surmise of three-dimensional mandibular morphology by cephalogram analysis. (author)

  18. Three-dimensional interpretation of TEM soundings

    Science.gov (United States)

    Barsukov, P. O.; Fainberg, E. B.

    2013-07-01

    We describe the approach to the interpretation of electromagnetic (EM) sounding data which iteratively adjusts the three-dimensional (3D) model of the environment by local one-dimensional (1D) transformations and inversions and reconstructs the geometrical skeleton of the model. The final 3D inversion is carried out with the minimal number of the sought parameters. At each step of the interpretation, the model of the medium is corrected according to the geological information. The practical examples of the suggested method are presented.

  19. Brown dwarfs forming in discs: Where to look for them?

    Directory of Open Access Journals (Sweden)

    Stamatellos D.

    2011-07-01

    Full Text Available A large fraction of the observed brown dwarfs may form by gravitational fragmentation of unstable discs. This model reproduces the brown dwarf desert, and provides an explanation for the existence of planetary-mass objects and for the binary properties of low-mass objects. We have performed an ensemble of radiative hydrodynamic simulations and determined the statistical properties of the low-mass objects produced by gravitational fragmentation of discs. We suggest that there is a population of brown dwarfs loosely bound on wide orbits (100–5000 AU around Sun-like stars that surveys of brown dwarf companions should target. Our simulations also indicate that planetary-mass companions to Sun-like stars are unlikely to form by disc fragmentation.

  20. Three-dimensional rotating flow of MHD single wall carbon nanotubes over a stretching sheet in presence of thermal radiation

    Science.gov (United States)

    Nasir, Saleem; Islam, Saeed; Gul, Taza; Shah, Zahir; Khan, Muhammad Altaf; Khan, Waris; Khan, Aurang Zeb; Khan, Saima

    2018-05-01

    In this article the modeling and computations are exposed to introduce the new idea of MHD three-dimensional rotating flow of nanofluid through a stretching sheet. Single wall carbon nanotubes (SWCNTs) are utilized as a nano-sized materials while water is used as a base liquid. Single-wall carbon nanotubes (SWNTs) parade sole assets due to their rare structure. Such structure has significant optical and electronics features, wonderful strength and elasticity, and high thermal and chemical permanence. The heat exchange phenomena are deliberated subject to thermal radiation and moreover the impact of nanoparticles Brownian motion and thermophoresis are involved in the present investigation. For the nanofluid transport mechanism, we implemented the Xue model (Xue, Phys B Condens Matter 368:302-307, 2005). The governing nonlinear formulation based upon the law of conservation of mass, quantity of motion, thermal field and nanoparticles concentrations is first modeled and then solved by homotopy analysis method (HAM). Moreover, the graphical result has been exposed to investigate that in what manner the velocities, heat and nanomaterial concentration distributions effected through influential parameters. The mathematical facts of skin friction, Nusselt number and Sherwood number are presented through numerical data for SWCNTs.

  1. Hypofractionated stereotactic radiation therapy in three to five fractions for vestibular schwannoma

    International Nuclear Information System (INIS)

    Morimoto, Masahiro; Yoshioka, Yasuo; Kotsuma, Tadayuki

    2013-01-01

    The objective of this study was to retrospectively examine the outcomes of hypofractionated stereotactic radiation therapy in three to five fractions for vestibular schwannomas. Twenty-five patients with 26 vestibular schwannomas were treated with hypofractionated stereotactic radiation therapy using a CyberKnife. The vestibular schwannomas of 5 patients were associated with type II neurofibromatosis. The median follow-up time was 80 months (range: 6-167); the median planning target volume was 2.6 cm 3 (0.3-15.4); and the median prescribed dose (≥D90) was 21 Gy in three fractions (18-25 Gy in three to five fractions). Progression was defined as ≥2 mm 3-dimensional post-treatment tumor enlargement excluding transient expansion. Progression or any death was counted as an event in progression-free survival rates, whereas only progression was counted in progression-free rates. The 7-year progression-free survival and progression-free rates were 78 and 95%, respectively. Late adverse events (≥3 months) with grades based on Common Terminology Criteria for Adverse Events, v4.03 were observed in 6 patients: Grade 3 hydrocephalus in one patient, Grade 2 facial nerve disorders in two and Grade 1-2 tinnitus in three. In total, 12 out of 25 patients maintained pure tone averages ≤50 dB before hypofractionated stereotactic radiation therapy, and 6 of these 12 patients (50%) maintained pure tone averages at this level at the final audiometric follow-up after hypofractionated stereotactic radiation therapy. However, gradient deterioration of pure tone average was observed in 11 of these 12 patients. The mean pure tone averages before hypofractionated stereotactic radiation therapy and at the final follow-up for the aforementioned 12 patients were 29.8 and 57.1 dB, respectively. Treating vestibular schwannomas with hypofractionated stereotactic radiation therapy in three to five fractions may prevent tumor progression with tolerable toxicity. However, gradient

  2. Hypofractionated stereotactic radiation therapy in three to five fractions for vestibular schwannoma

    Energy Technology Data Exchange (ETDEWEB)

    Morimoto, Masahiro; Yoshioka, Yasuo [Osaka Univ., Graduate School of Medicine, Suita, Osaka (Japan); Kotsuma, Tadayuki [Kinki-chuo Chest Medical Center, Sakai, Osaka (Japan); others, and

    2013-08-15

    The objective of this study was to retrospectively examine the outcomes of hypofractionated stereotactic radiation therapy in three to five fractions for vestibular schwannomas. Twenty-five patients with 26 vestibular schwannomas were treated with hypofractionated stereotactic radiation therapy using a CyberKnife. The vestibular schwannomas of 5 patients were associated with type II neurofibromatosis. The median follow-up time was 80 months (range: 6-167); the median planning target volume was 2.6 cm{sup 3} (0.3-15.4); and the median prescribed dose ({>=}D90) was 21 Gy in three fractions (18-25 Gy in three to five fractions). Progression was defined as {>=}2 mm 3-dimensional post-treatment tumor enlargement excluding transient expansion. Progression or any death was counted as an event in progression-free survival rates, whereas only progression was counted in progression-free rates. The 7-year progression-free survival and progression-free rates were 78 and 95%, respectively. Late adverse events ({>=}3 months) with grades based on Common Terminology Criteria for Adverse Events, v4.03 were observed in 6 patients: Grade 3 hydrocephalus in one patient, Grade 2 facial nerve disorders in two and Grade 1-2 tinnitus in three. In total, 12 out of 25 patients maintained pure tone averages {<=}50 dB before hypofractionated stereotactic radiation therapy, and 6 of these 12 patients (50%) maintained pure tone averages at this level at the final audiometric follow-up after hypofractionated stereotactic radiation therapy. However, gradient deterioration of pure tone average was observed in 11 of these 12 patients. The mean pure tone averages before hypofractionated stereotactic radiation therapy and at the final follow-up for the aforementioned 12 patients were 29.8 and 57.1 dB, respectively. Treating vestibular schwannomas with hypofractionated stereotactic radiation therapy in three to five fractions may prevent tumor progression with tolerable toxicity. However, gradient

  3. Three-dimensional imaging technology offers promise in medicine.

    Science.gov (United States)

    Karako, Kenji; Wu, Qiong; Gao, Jianjun

    2014-04-01

    Medical imaging plays an increasingly important role in the diagnosis and treatment of disease. Currently, medical equipment mainly has two-dimensional (2D) imaging systems. Although this conventional imaging largely satisfies clinical requirements, it cannot depict pathologic changes in 3 dimensions. The development of three-dimensional (3D) imaging technology has encouraged advances in medical imaging. Three-dimensional imaging technology offers doctors much more information on a pathology than 2D imaging, thus significantly improving diagnostic capability and the quality of treatment. Moreover, the combination of 3D imaging with augmented reality significantly improves surgical navigation process. The advantages of 3D imaging technology have made it an important component of technological progress in the field of medical imaging.

  4. The value of ultrasonic evaluation for diagnosis of lumbar disc herniation

    Energy Technology Data Exchange (ETDEWEB)

    Oh, Jae Cheon [Sarang Hospitl, Seoul (Korea, Republic of); Rhim, Hyun Chul; Jeong, Woo Koeng; Lee, Seung Ro [Hanyang University College of Medicine, Seoul (Korea, Republic of)

    2001-12-15

    The aim of the investigation was to evaluate the diagnostic effectiveness of sonography in the evaluation of the lower lumbar intervertebral disc herniations. Prospective ultrasonographic examinations by transabdominal approach were performed on 65 consecutive patients (32 males and 33 females) with clinically suspected lumbar disc herniation, and the findings were compared with MR findings. The transabdominal representation of lumbar disc herniations was successful in 64 cases at L3-4 level,59 cases at L4-5 level and 55 cases at L5-S1 level. The sonographic examination wa inconclusive in the some patients because of degenerative disc with vacuum phenomenon, osteophytosis and diminution of the intervertebal disc space. Both sensitivity and specificity of sonography were 100% at L3-4 level. At the same time, the sensitivity and specificity of sonography were 60% and 97% at L4-5 level and 36% and 100% at L5-S1 level. Although ultrasound is not currently used as a screening modality because of the low sensitivity, ultrasound shows a high specificity with non-invasiveness but without radiation hazard. Therefore, ultrasound can be used as an aid for diagnosing lumbar disc herniation, especially in young men without spondylosis.

  5. The value of ultrasonic evaluation for diagnosis of lumbar disc herniation

    International Nuclear Information System (INIS)

    Oh, Jae Cheon; Rhim, Hyun Chul; Jeong, Woo Koeng; Lee, Seung Ro

    2001-01-01

    The aim of the investigation was to evaluate the diagnostic effectiveness of sonography in the evaluation of the lower lumbar intervertebral disc herniations. Prospective ultrasonographic examinations by transabdominal approach were performed on 65 consecutive patients (32 males and 33 females) with clinically suspected lumbar disc herniation, and the findings were compared with MR findings. The transabdominal representation of lumbar disc herniations was successful in 64 cases at L3-4 level,59 cases at L4-5 level and 55 cases at L5-S1 level. The sonographic examination wa inconclusive in the some patients because of degenerative disc with vacuum phenomenon, osteophytosis and diminution of the intervertebal disc space. Both sensitivity and specificity of sonography were 100% at L3-4 level. At the same time, the sensitivity and specificity of sonography were 60% and 97% at L4-5 level and 36% and 100% at L5-S1 level. Although ultrasound is not currently used as a screening modality because of the low sensitivity, ultrasound shows a high specificity with non-invasiveness but without radiation hazard. Therefore, ultrasound can be used as an aid for diagnosing lumbar disc herniation, especially in young men without spondylosis.

  6. Three-dimensional echocardiographic assessment of the repaired mitral valve.

    Science.gov (United States)

    Maslow, Andrew; Mahmood, Feroze; Poppas, Athena; Singh, Arun

    2014-02-01

    This study examined the geometric changes of the mitral valve (MV) after repair using conventional and three-dimensional echocardiography. Prospective evaluation of consecutive patients undergoing mitral valve repair. Tertiary care university hospital. Fifty consecutive patients scheduled for elective repair of the mitral valve for regurgitant disease. Intraoperative transesophageal echocardiography. Assessments of valve area (MVA) were performed using two-dimensional planimetry (2D-Plan), pressure half-time (PHT), and three-dimensional planimetry (3D-Plan). In addition, the direction of ventricular inflow was assessed from the three-dimensional imaging. Good correlations (r = 0.83) and agreement (-0.08 +/- 0.43 cm(2)) were seen between the MVA measured with 3D-Plan and PHT, and were better than either compared to 2D-Plan. MVAs were smaller after repair of functional disease repaired with an annuloplasty ring. After repair, ventricular inflow was directed toward the lateral ventricular wall. Subgroup analysis showed that the change in inflow angle was not different after repair of functional disease (168 to 171 degrees) as compared to those presenting with degenerative disease (168 to 148 degrees; p<0.0001). Three-dimensional imaging provides caregivers with a unique ability to assess changes in valve function after mitral valve repair. Copyright © 2014 Elsevier Inc. All rights reserved.

  7. Disc operational system

    International Nuclear Information System (INIS)

    Veretenov, V.Yu.; Volkov, A.I.; Gurevich, M.I.; Kozik, V.S.; Pod'yachev, E.I.; Shapiro, M.L.

    1974-01-01

    A disc operational system is proposed, which is based on the file structure and designed for use in a BESM-6 computer with the software system comprising a dispatcher DD-73 and a monitor 'Dubna'. The main distinguishing feature of the disc operational system is the decentralization of the file system. Each disc package is an independent file unaffected by the state of the other disc packages. The use of several disc packages is allowed. The above feature of the disc operational system makes it possible to simplify the language of communication with the system, to give the user the opportunity of controlling the file quite independently, and to simplify the maintenance of the discs by the computer personnel. One and the same disc can be simultaneously addressed by all problems in the processor (both mathematical and service). A single file, however, may be used in the recording mode by only one problem. The description presented is the instruction for users. It also describes special possibilities open to the system programmers [ru

  8. Tactical Routing Using Two-Dimensional and Three-Dimensional Views of Terrain

    National Research Council Canada - National Science Library

    St

    2001-01-01

    Consoles for military and civilian occupations such as air warfare, command and control, air traffic control, piloting, and meteorological forecasting will be capable of displaying three-dimensional (3-D) perspective views...

  9. Three Dimensional Energy Transmitting Boundary in the Time Domain

    Directory of Open Access Journals (Sweden)

    Naohiro eNakamura

    2015-11-01

    Full Text Available Although the energy transmitting boundary is accurate and efficient for the FEM earthquake response analysis, it could be applied in the frequency domain only. In the previous papers, the author proposed an earthquake response analysis method using the time domain energy transmitting boundary for two dimensional problems. In this paper, this technique is expanded for three dimensional problems. The inner field is supposed to be a hexahedron shape and the approximate time domain boundary is explained, first. Next, two dimensional anti-plane time domain boundary is studied for a part of the approximate three dimensional boundary method. Then, accuracy and efficiency of the proposed method are confirmed by example problems.

  10. A method of image improvement in three-dimensional imaging

    International Nuclear Information System (INIS)

    Suto, Yasuzo; Huang, Tewen; Furuhata, Kentaro; Uchino, Masafumi.

    1988-01-01

    In general, image interpolation is required when the surface configurations of such structures as bones and organs are three-dimensionally constructed from the multi-sliced images obtained by CT. Image interpolation is a processing method whereby an artificial image is inserted between two adjacent slices to make spatial resolution equal to slice resolution in appearance. Such image interpolation makes it possible to increase the image quality of the constructed three-dimensional image. In our newly-developed algorithm, we have converted the presently and subsequently sliced images to distance images, and generated the interpolation images from these two distance images. As a result, compared with the previous method, three-dimensional images with better image quality have been constructed. (author)

  11. Usefulness Of Three-Dimensional Printing Models for Patients with Stoma Construction

    Directory of Open Access Journals (Sweden)

    Tetsuro Tominaga

    2016-04-01

    Full Text Available The use of patient-specific organ models in three-dimensional printing systems could be helpful for the education of patients and medical students. The aim of this study was to clarify whether the use of patient-specific stoma models is helpful for patient education. From January 2014 to September 2014, 5 patients who underwent colorectal surgery and for whom a temporary or permanent stoma had been created were involved in this study. Three-dimensional stoma models and three-dimensional face plates were created. The patients’ ages ranged from 59 to 81 years. Four patients underwent stoma construction because of rectal cancer, and 1 underwent stoma construction because of colon stenosis secondary to recurrent cancer. All patients were educated about their stoma and potential stoma-associated problems using three-dimensional stoma models, and all practiced cutting face plates using three-dimensional face plates. The models were also used during medical staff conferences to discuss current issues. All patients understood their problems and finally became self-reliant. The recent availability of three-dimensional printers has enabled the creation of many organ models, and full-scale stoma and face plate models are now available for patient education on cutting an appropriately individualized face plate. Thus, three-dimensional printers could enable fewer skin problems than are currently associated with daily stomal care.

  12. Three-dimensional ultrasound strain imaging of skeletal muscles

    NARCIS (Netherlands)

    Gijsbertse, Kaj; Sprengers, Andre M.; Nillesen, Maartje; Hansen, Hendrik H.G.; Verdonschot, Nico; De Korte, Chris L.

    2015-01-01

    Muscle contraction is characterized by large deformation and translation, which requires a multi-dimensional imaging modality to reveal its behavior. Previous work on ultrasound strain imaging of the muscle contraction was limited to 2D and bi-plane techniques. In this study, a three-dimensional

  13. CFD Modelling of the Effects of Operating Parameters on the Spreading of Liquids on a Spinning Disc

    Directory of Open Access Journals (Sweden)

    Y. Pan

    2014-03-01

    Full Text Available A novel dry slag granulation process based on a spinning disc is being developed by CSIRO. This process utilises centrifugal force to break up molten slag into droplets, which are then quenched into solidified granules by a flow of cold air. In this process the sensible heat of slag is recovered as hot air. In the present work, a previously developed steady-state, two-dimensional and multiphase CFD model was applied to perform parametric numerical experiments to investigate the effects of a number of parameters on the liquid film thickness at the disc edge, which included liquid mass feeding (pouring rate, disc spinning speed, disc radius, liquid viscosity, density and surface tension. The modelling results were compared with experimental data and were found to be in good agreement. To reduce the number of simulations needed, Box and Behnken's fractional factorial design of numerical experiment was adopted. Furthermore, in order for the modelling results to be applicable to atomisation of different liquids using spinning discs of different sizes, a dimensionless correlation was developed based on dimensional analysis of the numerical simulation data. The modelling results indicate that the liquid film thickness can be significantly influenced by the disc radius and spinning speed, the liquid mass feeding rate, viscosity and density, whereas the liquid surface tension has a negligible effect.

  14. The development and investigation of a prototype three-dimensional compensator for whole brain radiation therapy

    International Nuclear Information System (INIS)

    Keall, Paul; Arief, Isti; Shamas, Sofia; Weiss, Elisabeth; Castle, Steven

    2008-01-01

    Whole brain radiation therapy (WBRT) is the standard treatment for patients with brain metastases, and is often used in conjunction with stereotactic radiotherapy for patients with a limited number of brain metastases, as well as prophylactic cranial irradiation. The use of open fields (conventionally used for WBRT) leads to higher doses to the brain periphery if dose is prescribed to the brain center at the largest lateral radius. These dose variations potentially compromise treatment efficacy and translate to increased side effects. The goal of this research was to design and construct a 3D 'brain wedge' to compensate dose heterogeneities in WBRT. Radiation transport theory was invoked to calculate the desired shape of a wedge to achieve a uniform dose distribution at the sagittal plane for an ellipsoid irradiated medium. The calculations yielded a smooth 3D wedge design to account for the missing tissue at the peripheral areas of the brain. A wedge was machined based on the calculation results. Three ellipsoid phantoms, spanning the mean and ± two standard deviations from the mean cranial dimensions were constructed, representing 95% of the adult population. Film was placed at the sagittal plane for each of the three phantoms and irradiated with 6 MV photons, with the wedge in place. Sagittal plane isodose plots for the three phantoms demonstrated the feasibility of this wedge to create a homogeneous distribution with similar results observed for the three phantom sizes, indicating that a single wedge may be sufficient to cover 95% of the adult population. The sagittal dose is a reasonable estimate of the off-axis dose for whole brain radiation therapy. Comparing the dose with and without the wedge the average minimum dose was higher (90% versus 86%), the maximum dose was lower (107% versus 113%) and the dose variation was lower (one standard deviation 2.7% versus 4.6%). In summary, a simple and effective 3D wedge for whole brain radiotherapy has been developed

  15. Exact solutions in three-dimensional gravity

    CERN Document Server

    Garcia-Diaz, Alberto A

    2017-01-01

    A self-contained text, systematically presenting the determination and classification of exact solutions in three-dimensional Einstein gravity. This book explores the theoretical framework and general physical and geometrical characteristics of each class of solutions, and includes information on the researchers responsible for their discovery. Beginning with the physical character of the solutions, these are identified and ordered on the basis of their geometrical invariant properties, symmetries, and algebraic classifications, or from the standpoint of their physical nature, for example electrodynamic fields, fluid, scalar field, or dilaton. Consequently, this text serves as a thorough catalogue on 2+1 exact solutions to the Einstein equations coupled to matter and fields, and on vacuum solutions of topologically massive gravity with a cosmological constant. The solutions are also examined from different perspectives, enabling a conceptual bridge between exact solutions of three- and four-dimensional gravit...

  16. Identifying cell and molecular stress after radiation in a three-dimensional (3-D) model of oral mucositis

    International Nuclear Information System (INIS)

    Lambros, Maria Polikandritou; Parsa, Cyrus; Mulamalla, HariChandana; Orlando, Robert; Lau, Bernard; Huang, Ying; Pon, Doreen; Chow, Moses

    2011-01-01

    Research highlights: → We irradiated a 3-D human oral cell culture of keratinocytes and fibroblasts with 12 and 2 Gy. → 6 h after irradiation the histopathology and apoptosis of the 3-D culture were evaluated. Microarrays were used to assess the gene expression in the irradiated 3-D tissue. → 12 Gy induced significant histopathologic changes and cellular apoptosis. → 12 Gy significantly affected genes of the NF-kB pathway, inflammatory cytokines and DAMPs. -- Abstract: Mucositis is a debilitating adverse effect of chemotherapy and radiation treatment. It is important to develop a simple and reliable in vitro model, which can routinely be used to screen new drugs for prevention and treatment of mucositis. Furthermore, identifying cell and molecular stresses especially in the initiation phase of mucositis in this model will help towards this end. We evaluated a three-dimensional (3-D) human oral cell culture that consisted of oral keratinocytes and fibroblasts as a model of oral mucositis. The 3-D cell culture model was irradiated with 12 or 2 Gy. Six hours after the irradiation we evaluated microscopic sections of the cell culture for evidence of morphologic changes including apoptosis. We used microarrays to compare the expression of several genes from the irradiated tissue with identical genes from tissue that was not irradiated. We found that irradiation with 12 Gy induced significant histopathologic effects including cellular apoptosis. Irradiation significantly affected the expression of several genes of the NF-kB pathway and several inflammatory cytokines, such as IL-1B, 1L-8, NF-kB1, and FOS compared to tissue that was not irradiated. We identified significant upregulation of several genes that belong to damage-associated molecular patterns (DAMPs) such as HMB1, S100A13, SA10014, and SA10016 in the 3-D tissues that received 12 Gy but not in tissues that received 2 Gy. In conclusion, this model quantifies radiation damage and this is an important first

  17. Microfabrication and Magnetic Particle Spectrometry of Magnetic Discs

    NARCIS (Netherlands)

    Löthman, Per Arvid; Janson, T.G.; Klein, Yannick Philippe; Blaudszun, André-René; Ledwig, Michael; Abelmann, Leon

    2017-01-01

    We report on the fabrication of dispersions of Au/Ni81Fe19/Au magnetic discs with two and three micrometer diameter and thickness in the order of hundred nanometers. The magnetisation reversal of the discs was analysed on a time-scale of an hour as well as a few milliseconds to asses their

  18. Fracture mechanics by three-dimensional crack-tip synchrotron X-ray microscopy.

    Science.gov (United States)

    Withers, P J

    2015-03-06

    To better understand the relationship between the nucleation and growth of defects and the local stresses and phase changes that cause them, we need both imaging and stress mapping. Here, we explore how this can be achieved by bringing together synchrotron X-ray diffraction and tomographic imaging. Conventionally, these are undertaken on separate synchrotron beamlines; however, instruments capable of both imaging and diffraction are beginning to emerge, such as ID15 at the European Synchrotron Radiation Facility and JEEP at the Diamond Light Source. This review explores the concept of three-dimensional crack-tip X-ray microscopy, bringing them together to probe the crack-tip behaviour under realistic environmental and loading conditions and to extract quantitative fracture mechanics information about the local crack-tip environment. X-ray diffraction provides information about the crack-tip stress field, phase transformations, plastic zone and crack-face tractions and forces. Time-lapse CT, besides providing information about the three-dimensional nature of the crack and its local growth rate, can also provide information as to the activation of extrinsic toughening mechanisms such as crack deflection, crack-tip zone shielding, crack bridging and crack closure. It is shown how crack-tip microscopy allows a quantitative measure of the crack-tip driving force via the stress intensity factor or the crack-tip opening displacement. Finally, further opportunities for synchrotron X-ray microscopy are explored.

  19. Cervical disc hernia operations through posterior laminoforaminotomy

    Directory of Open Access Journals (Sweden)

    Coskun Yolas

    2016-01-01

    Full Text Available Objective: The most common used technique for posterolateral cervical disc herniations is anterior approach. However, posterior cervical laminotoforaminomy can provide excellent results in appropriately selected patients with foraminal stenosis in either soft disc prolapse or cervical spondylosis. The purpose of this study was to present the clinical outcomes following posterior laminoforaminotomy in patients with radiculopathy. Materials and Methods: We retrospectively evaluated 35 patients diagnosed with posterolateral cervical disc herniation and cervical spondylosis with foraminal stenosis causing radiculopathy operated by the posterior cervical keyhole laminoforaminotomy between the years 2010 and 2015. Results: The file records and the radiographic images of the 35 patients were assessed retrospectively. The mean age was 46.4 years (range: 34-66 years. Of the patients, 19 were males and 16 were females. In all of the patients, the neurologic deficit observed was radiculopathy. The posterolaterally localized disc herniations and the osteophytic structures were on the left side in 18 cases and on the right in 17 cases. In 10 of the patients, the disc level was at C5-6, in 18 at C6-7, in 2 at C3-4, in 2 at C4-5, in 1 at C7-T1, in 1 patient at both C5-6 and C6-7, and in 1 at both C4-5 and C5-6. In 14 of these 35 patients, both osteophytic structures and protruded disc herniation were present. Intervertebral foramen stenosis was present in all of the patients with osteophytes. Postoperatively, in 31 patients the complaints were relieved completely and four patients had complaints of neck pain and paresthesia radiating to the arm (the success of operation was 88.5%. On control examinations, there was no finding of instability or cervical kyphosis. Conclusion: Posterior cervical laminoforaminotomy is an alternative appropriate choice in both cervical soft disc herniations and cervical stenosis.

  20. Three-dimensional reacting shock–bubble interaction

    NARCIS (Netherlands)

    Diegelmann, Felix; Hickel, S.; Adams, Nikolaus A.

    2017-01-01

    We investigate a reacting shock–bubble interaction through three-dimensional numerical simulations with detailed chemistry. The convex shape of the bubble focuses the shock and generates regions of high pressure and temperature, which are sufficient to ignite the diluted stoichiometric

  1. Collapse in a forced three-dimensional nonlinear Schrodinger equation

    DEFF Research Database (Denmark)

    Lushnikov, P.M.; Saffman, M.

    2000-01-01

    We derive sufficient conditions for the occurrence of collapse in a forced three-dimensional nonlinear Schrodinger equation without dissipation. Numerical studies continue the results to the case of finite dissipation.......We derive sufficient conditions for the occurrence of collapse in a forced three-dimensional nonlinear Schrodinger equation without dissipation. Numerical studies continue the results to the case of finite dissipation....

  2. A finite element study on the effects of midsymphyseal distraction osteogenesis on the mandible and articular disc.

    Science.gov (United States)

    Kim, Ki-Nam; Cha, Bong-Kuen; Choi, Dong-Soon; Jang, Insan; Yi, Yang-Jin; Jost-Brinkmann, Paul-Georg

    2012-05-01

    To evaluate the biomechanical effect of midsymphyseal distraction osteogenesis with three types of distractors on the mandible and articular disc using a three-dimensional finite element model analysis. A virtual model of the mandible was produced from computed tomography scan images of a healthy 27-year-old man. On the finite element model of the mandible, expansion of the bone-borne, tooth-borne, and hybrid type distractors were simulated with the jaw-closing muscles. The displacement and stress distribution of the mandible and articular disc were analyzed. With the bone-borne appliance the alveolar process area was displaced more than the basal bone area. The tooth-borne appliance displaced the mandibular body in a parallel manner and showed high level of the von Mises stress in the alveolar process and the ramal region as well as in the condylar neck area. The hybrid type showed medium amount of displacement and stress distribution compared with the bone-borne and tooth-borne type. At the articular disc the compressive stress was concentrated in the anteromedial and posterolateral area, and it was highest in the tooth-borne distractor, followed by hybrid appliance and bone-borne appliance. The tooth-borne distractor produced more parallel bony widening in the midsymphyseal area and larger expansion in the molar region; however, it induced higher stress concentration on the articular disc than the hybrid appliance and bone-borne appliance. Whether any long-term side effects on the temporomandibular joint are anticipated, especially in tooth-borne distractor, remains to be investigated.

  3. Eustachian tube three-dimensional reconstruction of secretory otitis media

    International Nuclear Information System (INIS)

    Yu Yafeng; Zhou Weirong; Bao Xueping; Li Min; Hu Zhenmin

    2006-01-01

    Objective: To study relationship between Eustachian tube and secretory otitis media and to explore the pathogeny of secretory otitis by three-dimensional reconstruction of Eustachian tube. Methods: Thirty cases of secretory otitis media (male 19, female 11) were selected randomly. Everyone was checked by otoscope and audiometry. Their bilateral Eustachian tubes were scanning by helix CT while making Valsalva's action. All images were passed on to work station to make three-dimensional reconstruction. Results: Four patients were found have Eustachian tube diseases, while most of patients' Eustachian tubes ventilated normally. Conclusions: Three-dimensional reconstruction of Eustachian tube can open out some pathogens of some secretory otitis medias. It will be helpful to diagnosis and therapy of secretory otitis media. (authors)

  4. Computerized three-dimensional normal atlas

    International Nuclear Information System (INIS)

    Mano, Isamu; Suto, Yasuzo; Suzuki, Masataka; Iio, Masahiro.

    1990-01-01

    This paper presents our ongoing project in which normal human anatomy and its quantitative data are systematically arranged in a computer. The final product, the Computerized Three-Dimensional Normal Atlas, will be able to supply tomographic images in any direction, 3-D images, and coded information on organs, e.g., anatomical names, CT numbers, and T 1 and T 2 values. (author)

  5. Three-Dimensional Shallow Water Acoustics

    Science.gov (United States)

    2016-03-30

    medium properties, so horizontal refraction and reflection of sound can occur and produce significant three-dimensional (3-D) sound propagation ...by the environmental factors existing commonly in the continental shelf and shelfbreak areas, such as slopes, submarine canyons, sub-bottom layers ...surface waves, internal waves and shelfbreak fronts. 15. SUBJECT TERMS Continental Shelf; 3-D Acoustics , Surface Waves, Sound Propagation 16

  6. Real-time three dimensional transesophageal echocardiography: technical aspects and clinical applications

    Directory of Open Access Journals (Sweden)

    Sergio Mondillo

    2010-02-01

    Full Text Available Real-time three-dimensional transeso-phageal echocardiography (RT3DTEE is now commonly used in daily clinical practice. The transesophageal, compared to the transthoracic approach, allows the visualization of the whole spectrum of the mitral valve apparatus and the posterior cardiac structures. Moreover, images obtained by RT 3D TEE provide a unique and complete visualization of the mitral valve prosthetic elements. Indeed, the possibility to visualize guidewires and catheters in cardiac chambers and their relationship with cardiac structures during percutaneous transcatheter procedures reduces the time of radiation exposure and simplifies the approach becoming the reference method for monitoring. This review aims to underline the potential clinical applications and the advantages of RT3DTEE compared to other methods.

  7. Variation of clinical target volume definition in three-dimensional conformal radiation therapy for prostate cancer

    International Nuclear Information System (INIS)

    Valicenti, Richard K.; Sweet, John W.; Hauck, Walter W.; Hudes, Richard S.; Lee, Tony; Dicker, Adam P.; Waterman, Frank M.; Anne, Pramila R.; Corn, Benjamin W.; Galvin, James M.

    1999-01-01

    Purpose: Currently, three-dimensional conformal radiation therapy (3D-CRT) planning relies on the interpretation of computed tomography (CT) axial images for defining the clinical target volume (CTV). This study investigates the variation among multiple observers to define the CTV used in 3D-CRT for prostate cancer. Methods and Materials: Seven observers independently delineated the CTVs (prostate ± seminal vesicles [SV]) from the CT simulation data of 10 prostate cancer patients undergoing 3D-CRT. Six patients underwent CT simulation without the use of contrast material and serve as a control group. The other 4 had urethral and bladder opacification with contrast medium. To determine interobserver variation, we evaluated the derived volume, the maximum dimensions, and the isocenter for each examination of CTV. We assessed the reliability in the CTVs among the observers by correlating the variation for each class of measurements. This was estimated by intraclass correlation coefficient (ICC), with 1.00 defining absolute correlation. Results: For the prostate volumes, the ICC was 0.80 (95% confidence interval [CI]: 0.56-0.96). This changed to 0.92 (95% CI: 0.75-0.99) with the use of contrast material. Similarly, the maximal prostatic dimensions were reliable and improved. There was poor agreement in defining the SV. For this structure, the ICC never exceeded 0.28. The reliability of the isocenter was excellent, with the ICC exceeding 0.83 and 0.90 for the prostate ± SV, respectively. Conclusions: In 3D-CRT for prostate cancer, there was excellent agreement among multiple observers to define the prostate target volume but poor agreement to define the SV. The use of urethral and bladder contrast improved the reliability of localizing the prostate. For all CTVs, the isocenter was very reliable and should be used to compare the variation in 3D dosimetry among multiple observers

  8. Three dimensional CT imaging of ossicular chain: a preliminary study

    International Nuclear Information System (INIS)

    Hu Chunhong; Zhong Shenbin; Fu Yindi; Zhu Wei; Wang Xueyuan; Chen Jianhua; Ding Yi

    2001-01-01

    Objective: To analysis the features of normal and abnormal ossicular chain in three dimensional images and asses the best parameters and its usefulness in diagnosis and treatment of chronic otitis media (COM). Methods: All patients, including 43 patients with normal ears and 24 ears with COM, were examined using spiral CT with inner ear software, 1-mm slice width and 1 pitch. SSD method was used in three dimensional reconstruction and the threshold was 100-300 Hu. Results: In normal cases, Malleus, incus, stapes crura, incudomalleal joints and incudostapedial joints were displayed well, but stapes footplate unsatisfactorily. The disruption of the ossicular chain showed in three-dimensional images in cases of chronic otitis media was in accord with that seen in the operation. Conclusion: It is very important for imaging with high quality through selecting proper parameters, and three-dimensional image can provide valuable information for surgery

  9. Three dimensional digital imaging of environmental data

    International Nuclear Information System (INIS)

    Nichols, R.L.; Eddy, C.A.

    1991-01-01

    The Environmental Sciences Section (ESS) of the Savannah River Laboratory has recently acquired the computer hardware (Silicon Graphics Personal Iris Workstations) and software (Dynamic Graphics, Interactive Surface and Volume Modeling) to perform three dimensional analysis of hydrogeologic data. Three dimensional digital imaging of environmental data is a powerful technique that can be used to incorporate field, analytical, and modeling results from geologic, hydrologic, ecologic, and chemical studies into a comprehensive model for visualization and interpretation. This report covers the contamination of four different sites of the Savannah River Plant. Each section of this report has a computer graphic display of the concentration of contamination in the groundwater and/or sediments of each site

  10. Three-dimensional Imaging, Visualization, and Display

    CERN Document Server

    Javidi, Bahram; Son, Jung-Young

    2009-01-01

    Three-Dimensional Imaging, Visualization, and Display describes recent developments, as well as the prospects and challenges facing 3D imaging, visualization, and display systems and devices. With the rapid advances in electronics, hardware, and software, 3D imaging techniques can now be implemented with commercially available components and can be used for many applications. This volume discusses the state-of-the-art in 3D display and visualization technologies, including binocular, multi-view, holographic, and image reproduction and capture techniques. It also covers 3D optical systems, 3D display instruments, 3D imaging applications, and details several attractive methods for producing 3D moving pictures. This book integrates the background material with new advances and applications in the field, and the available online supplement will include full color videos of 3D display systems. Three-Dimensional Imaging, Visualization, and Display is suitable for electrical engineers, computer scientists, optical e...

  11. RESULTS OF TREATMENT OF ACUTE LUMBAR DISC HERNIATION WITH TRANSFORAMINAL NERVE ROOT BLOCK

    Directory of Open Access Journals (Sweden)

    EMILIANO NEVES VIALLE

    Full Text Available ABSTRACT Objective: To determine the efficacy of anesthetic transforaminal nerve root block in patients with sciatica secondary to lumbar disc herniation through a prospective observational study. Methods: The study included 176 patients from a private clinic undergoing transforaminal injection performed by a single spinal surgeon. The patients were assessed after two weeks, three months and six months regarding to the improvement of the pain radiating to the lower limbs. In case of persistent symptoms, patients could choose to perform a new nerve root block and maintenance of physical therapy or be submitted to conventional microdiscectomy. Results: By the end of six-month follow-up of the 176 patients, 116 had a favorable outcome (95 after one block and 21 after two blocks, and only 43 required surgery. Conclusion: The results of our study suggest a positive effect of transforaminal block for the treatment of sciatica in patients with lumbar disc herniation.

  12. The role of Gd-enhanced three-dimensional MRI fast low-angle shot (FLASH) in the evaluation of symptomatic lumbosacral nerve roots

    Energy Technology Data Exchange (ETDEWEB)

    Kikkawa, Ichiro; Sugimoto, Hideharu; Saita, Kazuo; Ookami, Hitoshi; Nakama, Sueo; Hoshino, Yuichi [Jichi Medical School, Minamikawachi, Tochigi (Japan)

    2001-07-01

    In the field of lumbar spine disorders, three-dimensional (3-D) magnetic resonance imaging (MRI) can clearly depict a lumbar nerve root from the distal region to the dorsal root ganglion. In this study, we used a gadoliniumdiethylenetriaminepentaacetic acid (Gd-DTPA) enhanced-three-dimensional (3-D) fast low-angle shot (FLASH) sequence when examining lumbosacral disorders. The subjects were 33 patients (14 men and 19 women) in whom lumbosacral neural compression had been diagnosed clinically. Twenty-one patients had lumbar disc herniation, 11 had lumbar spinal stenosis, and 1 had lumbar radiculopathy caused by rheumatoid arthritis. Five subjects with low back pain were also studied as a control group. In all patients and in all 5 of the controls, the dorsal root ganglion of every root was enhanced clearly. There was no root enhancement in the 5 controls. Enhancement of the symptomatic nerve roots, caused by compression, was found in 11 of the 33 patients. All 11 patients had rediculopathy, and muscle weakness was more frequent in patients with enhanced nerve roots than in those without enhancement. There was no enhancement of the cauda equina, even in the patients with cauda syndrome. The enhancement effect may reflect some pathological condition of the compressed nerve root and needs to be studied further. (author)

  13. The role of Gd-enhanced three-dimensional MRI fast low-angle shot (FLASH) in the evaluation of symptomatic lumbosacral nerve roots

    International Nuclear Information System (INIS)

    Kikkawa, Ichiro; Sugimoto, Hideharu; Saita, Kazuo; Ookami, Hitoshi; Nakama, Sueo; Hoshino, Yuichi

    2001-01-01

    In the field of lumbar spine disorders, three-dimensional (3-D) magnetic resonance imaging (MRI) can clearly depict a lumbar nerve root from the distal region to the dorsal root ganglion. In this study, we used a gadoliniumdiethylenetriaminepentaacetic acid (Gd-DTPA) enhanced-three-dimensional (3-D) fast low-angle shot (FLASH) sequence when examining lumbosacral disorders. The subjects were 33 patients (14 men and 19 women) in whom lumbosacral neural compression had been diagnosed clinically. Twenty-one patients had lumbar disc herniation, 11 had lumbar spinal stenosis, and 1 had lumbar radiculopathy caused by rheumatoid arthritis. Five subjects with low back pain were also studied as a control group. In all patients and in all 5 of the controls, the dorsal root ganglion of every root was enhanced clearly. There was no root enhancement in the 5 controls. Enhancement of the symptomatic nerve roots, caused by compression, was found in 11 of the 33 patients. All 11 patients had rediculopathy, and muscle weakness was more frequent in patients with enhanced nerve roots than in those without enhancement. There was no enhancement of the cauda equina, even in the patients with cauda syndrome. The enhancement effect may reflect some pathological condition of the compressed nerve root and needs to be studied further. (author)

  14. Three-dimensional monochromatic x-ray computed tomography using synchrotron radiation

    Science.gov (United States)

    Saito, Tsuneo; Kudo, Hiroyuki; Takeda, Tohoru; Itai, Yuji; Tokumori, Kenji; Toyofuku, Fukai; Hyodo, Kazuyuki; Ando, Masami; Nishimura, Katsuyuki; Uyama, Chikao

    1998-08-01

    We describe a technique of 3D computed tomography (3D CT) using monochromatic x rays generated by synchrotron radiation, which performs a direct reconstruction of a 3D volume image of an object from its cone-beam projections. For the development, we propose a practical scanning orbit of the x-ray source to obtain complete 3D information on an object, and its corresponding 3D image reconstruction algorithm. The validity and usefulness of the proposed scanning orbit and reconstruction algorithm were confirmed by computer simulation studies. Based on these investigations, we have developed a prototype 3D monochromatic x-ray CT using synchrotron radiation, which provides exact 3D reconstruction and material-selective imaging by using the K-edge energy subtraction technique.

  15. Three-dimensional cooling of muons

    CERN Document Server

    Vsevolozhskaya, T A

    2000-01-01

    The simultaneous ionization cooling of muon beams in all three - the longitudinal and two transverse - directions is considered in a scheme, based on bent lithium lenses with dipole constituent of magnetic field in them, created by a special configuration of current-carrying rod. An analysis of three-dimensional cooling is performed with the use of kinetic equation method. Results of numerical calculation for a specific beam line configuration are presented together with results of computer simulation using the Moliere distribution to describe the Coulomb scattering and the Vavilov distribution used to describe the ionization loss of energy.

  16. Vibrational spectra and thermal rectification in three-dimensional anharmonic lattices

    International Nuclear Information System (INIS)

    Lan Jinghua; Li Baowen

    2007-01-01

    We study thermal rectification in a three-dimensional model consisting of two segments of anharmonic lattices. One segment consists of layers of harmonic oscillator arrays coupled to a substrate potential, which is a three-dimensional Frenkel-Kontorova model, and the other segment is a three-dimensional Fermi-Pasta-Ulam model. We study the vibrational bands of the two lattices analytically and numerically, and find that, by choosing the system parameters properly, the rectification can be as high as a few thousands, which is high enough to be observed in experiment. Possible experiments in nanostructures are discussed

  17. Characterizing College Science Assessments: The Three-Dimensional Learning Assessment Protocol

    Science.gov (United States)

    Underwood, Sonia M.; Matz, Rebecca L.; Posey, Lynmarie A.; Carmel, Justin H.; Caballero, Marcos D.; Fata-Hartley, Cori L.; Ebert-May, Diane; Jardeleza, Sarah E.; Cooper, Melanie M.

    2016-01-01

    Many calls to improve science education in college and university settings have focused on improving instructor pedagogy. Meanwhile, science education at the K-12 level is undergoing significant changes as a result of the emphasis on scientific and engineering practices, crosscutting concepts, and disciplinary core ideas. This framework of “three-dimensional learning” is based on the literature about how people learn science and how we can help students put their knowledge to use. Recently, similar changes are underway in higher education by incorporating three-dimensional learning into college science courses. As these transformations move forward, it will become important to assess three-dimensional learning both to align assessments with the learning environment, and to assess the extent of the transformations. In this paper we introduce the Three-Dimensional Learning Assessment Protocol (3D-LAP), which is designed to characterize and support the development of assessment tasks in biology, chemistry, and physics that align with transformation efforts. We describe the development process used by our interdisciplinary team, discuss the validity and reliability of the protocol, and provide evidence that the protocol can distinguish between assessments that have the potential to elicit evidence of three-dimensional learning and those that do not. PMID:27606671

  18. Characterizing College Science Assessments: The Three-Dimensional Learning Assessment Protocol.

    Science.gov (United States)

    Laverty, James T; Underwood, Sonia M; Matz, Rebecca L; Posey, Lynmarie A; Carmel, Justin H; Caballero, Marcos D; Fata-Hartley, Cori L; Ebert-May, Diane; Jardeleza, Sarah E; Cooper, Melanie M

    2016-01-01

    Many calls to improve science education in college and university settings have focused on improving instructor pedagogy. Meanwhile, science education at the K-12 level is undergoing significant changes as a result of the emphasis on scientific and engineering practices, crosscutting concepts, and disciplinary core ideas. This framework of "three-dimensional learning" is based on the literature about how people learn science and how we can help students put their knowledge to use. Recently, similar changes are underway in higher education by incorporating three-dimensional learning into college science courses. As these transformations move forward, it will become important to assess three-dimensional learning both to align assessments with the learning environment, and to assess the extent of the transformations. In this paper we introduce the Three-Dimensional Learning Assessment Protocol (3D-LAP), which is designed to characterize and support the development of assessment tasks in biology, chemistry, and physics that align with transformation efforts. We describe the development process used by our interdisciplinary team, discuss the validity and reliability of the protocol, and provide evidence that the protocol can distinguish between assessments that have the potential to elicit evidence of three-dimensional learning and those that do not.

  19. Three-dimensional simulation of thermal harmonic lasing free electron laser with detuning of the fundamental

    Science.gov (United States)

    Salehi, E.; Maraghechi, B.; Mirian, N. S.

    2016-03-01

    Detuning of the fundamental is a way to enhance harmonic generation. By this method, the wiggler is composed of two segments in such a way that the fundamental resonance of the second segment to coincide with the third harmonic of the first segment of the wiggler to generate extreme ultraviolet radiation and x-ray emission. A set of coupled, nonlinear, and first-order differential equations in three dimensions describing the evolution of the electron trajectories and the radiation field with warm beam is solved numerically by CYRUS 3D code in the steady-state for two models (1) seeded free electron laser (FEL) and (2) shot noise on the electron beam (self-amplified spontaneous emission FEL). Thermal effects in the form of longitudinal velocity spread are considered. Three-dimensional simulation describes self-consistently the longitudinal spatial dependence of radiation waists, curvatures, and amplitudes together with the evaluation of the electron beam. The evolutions of the transverse modes are investigated for the fundamental resonance and the third harmonic. Also, the effective modes of the third harmonic are studied. In this paper, we found that detuning of the fundamental with shot noise gives more optimistic result than the seeded FEL.

  20. Three-dimensional simulation of thermal harmonic lasing free electron laser with detuning of the fundamental

    International Nuclear Information System (INIS)

    Salehi, E.; Maraghechi, B.; Mirian, N. S.

    2016-01-01

    Detuning of the fundamental is a way to enhance harmonic generation. By this method, the wiggler is composed of two segments in such a way that the fundamental resonance of the second segment to coincide with the third harmonic of the first segment of the wiggler to generate extreme ultraviolet radiation and x-ray emission. A set of coupled, nonlinear, and first-order differential equations in three dimensions describing the evolution of the electron trajectories and the radiation field with warm beam is solved numerically by CYRUS 3D code in the steady-state for two models (1) seeded free electron laser (FEL) and (2) shot noise on the electron beam (self-amplified spontaneous emission FEL). Thermal effects in the form of longitudinal velocity spread are considered. Three-dimensional simulation describes self-consistently the longitudinal spatial dependence of radiation waists, curvatures, and amplitudes together with the evaluation of the electron beam. The evolutions of the transverse modes are investigated for the fundamental resonance and the third harmonic. Also, the effective modes of the third harmonic are studied. In this paper, we found that detuning of the fundamental with shot noise gives more optimistic result than the seeded FEL.

  1. Three-dimensional simulation of thermal harmonic lasing free electron laser with detuning of the fundamental

    Energy Technology Data Exchange (ETDEWEB)

    Salehi, E. [Department of Physics, Amirkabir University of Technology, 15875-4413 Tehran (Iran, Islamic Republic of); Maraghechi, B., E-mail: behrouz@aut.ac.ir [Department of Physics, Amirkabir University of Technology, 15875-4413 Tehran (Iran, Islamic Republic of); School of Particle and Accelerator Physics, Institute for Research in Fundamental Sciences (IPM), 19395-5531 Tehran (Iran, Islamic Republic of); Mirian, N. S. [School of Particle and Accelerator Physics, Institute for Research in Fundamental Sciences (IPM), 19395-5531 Tehran (Iran, Islamic Republic of); UVSOR Facility (UVSOR), Institute for Molecular Science, Myodaiji, Okazaki 444-8585 (Japan)

    2016-03-15

    Detuning of the fundamental is a way to enhance harmonic generation. By this method, the wiggler is composed of two segments in such a way that the fundamental resonance of the second segment to coincide with the third harmonic of the first segment of the wiggler to generate extreme ultraviolet radiation and x-ray emission. A set of coupled, nonlinear, and first-order differential equations in three dimensions describing the evolution of the electron trajectories and the radiation field with warm beam is solved numerically by CYRUS 3D code in the steady-state for two models (1) seeded free electron laser (FEL) and (2) shot noise on the electron beam (self-amplified spontaneous emission FEL). Thermal effects in the form of longitudinal velocity spread are considered. Three-dimensional simulation describes self-consistently the longitudinal spatial dependence of radiation waists, curvatures, and amplitudes together with the evaluation of the electron beam. The evolutions of the transverse modes are investigated for the fundamental resonance and the third harmonic. Also, the effective modes of the third harmonic are studied. In this paper, we found that detuning of the fundamental with shot noise gives more optimistic result than the seeded FEL.

  2. Radiation detecting system

    International Nuclear Information System (INIS)

    1975-01-01

    In spectrophotometry systems, a usual arrangement for modulating the radiation is a rotating disc having one or more sectors removed. A beam of radiation may be blocked by the disc except when a cut-away sector is in the path of the beam. With a double-beam system, a cut-away sector of 180 0 may be used so that when the first path is blocked, the second is allowed through, and vice versa. One or both sides of the disc may be formed as mirrors to facilitate beam switching and to allow use of more than two beams for background compensation purposes or for analysis of more than one substance within a sample. (G.T.H.)

  3. Three dimensional imaging technique for laser-plasma diagnostics

    International Nuclear Information System (INIS)

    Jiang Shaoen; Zheng Zhijian; Liu Zhongli

    2001-01-01

    A CT technique for laser-plasma diagnostic and a three-dimensional (3D) image reconstruction program (CT3D) have been developed. The 3D images of the laser-plasma are reconstructed by using a multiplication algebraic reconstruction technique (MART) from five pinhole camera images obtained along different sight directions. The technique has been used to measure the three-dimensional distribution of X-ray of laser-plasma experiments in Xingguang II device, and the good results are obtained. This shows that a CT technique can be applied to ICF experiments

  4. Three dimensional imaging technique for laser-plasma diagnostics

    Energy Technology Data Exchange (ETDEWEB)

    Shaoen, Jiang; Zhijian, Zheng; Zhongli, Liu [China Academy of Engineering Physics, Chengdu (China)

    2001-04-01

    A CT technique for laser-plasma diagnostic and a three-dimensional (3D) image reconstruction program (CT3D) have been developed. The 3D images of the laser-plasma are reconstructed by using a multiplication algebraic reconstruction technique (MART) from five pinhole camera images obtained along different sight directions. The technique has been used to measure the three-dimensional distribution of X-ray of laser-plasma experiments in Xingguang II device, and the good results are obtained. This shows that a CT technique can be applied to ICF experiments.

  5. Three-dimensional Reciprocal Structures: Morphology, Concepts, Generative Rules

    DEFF Research Database (Denmark)

    Parigi, Dario; Pugnale, Alberto

    2012-01-01

    , causing every configuration to develop naturally out-of the plane. The structures presented here were developed and built by the students of the Master of Science in “Architectural Design” during a two week long workshop organized at Aalborg University in the fall semester 2011.......This paper present seven different three dimensional structures based on the principle of structural reciprocity with superimposition joint and standardized un-notched elements. Such typology could be regarded as being intrinsically three-dimensional because elements sit one of the top of the other...

  6. Flukacad/Pipsicad: three-dimensional interfaces between Fluka and Autocad

    International Nuclear Information System (INIS)

    Helmut Vincke

    2001-01-01

    FLUKA is a widely used 3-D particle transport program. Up to now there was no possibility to display the simulation geometry or the calculated tracks in three dimensions. Even with FLUKA there exists only an option to picture two-dimensional views through the geometry used. This paper covers the description of two interface programs between the particle transport code FLUKA and the CAD program AutoCAD. These programs provide a three-dimensional facility not only for illustrating the simulated FLUKA geometry (FLUKACAD), but also for picturing simulated particle tracks (PIPSICAD) in a three-dimensional set-up. Additionally, the programming strategy for connecting FLUKA with AutoCAD is shown. A number of useful features of the programs themselves, but also of AutoCAD in the context of FLUKACAD and PIPSICAD, are explained. (authors)

  7. Usefulness of three dimensional reconstructive images for thoracic trauma induced fractures

    Energy Technology Data Exchange (ETDEWEB)

    Koh, Kyung Hun; Kim, Dong Hun; Kim, Young Sook; Byun, Joo Nam [Chosun University Hospital, Gwangju (Korea, Republic of)

    2006-09-15

    We wanted to evaluate the usefulness of three-dimensional reconstructive images using multidetector computed tomography (MDCT) for thoracic traumatic patients visiting emergency room. 76 patients with fractures of the 105 patients who visited our emergency room with complaints of thoracic trauma were analyzed retrospectively. All the patients had thoracic MDCT performed and the three-dimensional reconstructive images were taken. The fractures were confirmed by axial CT, the clinical information, whole body bone scanning and the multiplanar reformation images. Plain x-ray images were analyzed by the fractured sites in a blind comparison of two radiologists' readings, and then that finding was compared with the axial CT scans and the three-dimensional reconstructive images. The fracture sites were rib (n 68), sternum (n = 14), clavicle (n = 6), scapula (n = 3), spine (n = 5) and combined fractures (n = 14). Plain x-ray and axial CT scans had a correspondency of 0.555 for the rib fractures. Axial CT scans and the three-dimensional reconstructive images had a correspondency of .952. For sternal fractures, those values were 0.692 and 0.928, respectively. The axial CT scans and three-dimensional reconstructive images showed sensitivities of 94% and 91% for rib and other fractures, respectively, and 93% and 100% for sternal fracture, respectively. Three-dimensional reconstructive image had an especially high sensitivity for the diagnosis of sternal fracture. While evaluating thoracic trauma at the emergency room, the three-dimensional reconstructive image was useful to easily diagnose the extent of fracture and it was very sensitive for detecting sternal fracture.

  8. Usefulness of three dimensional reconstructive images for thoracic trauma induced fractures

    International Nuclear Information System (INIS)

    Koh, Kyung Hun; Kim, Dong Hun; Kim, Young Sook; Byun, Joo Nam

    2006-01-01

    We wanted to evaluate the usefulness of three-dimensional reconstructive images using multidetector computed tomography (MDCT) for thoracic traumatic patients visiting emergency room. 76 patients with fractures of the 105 patients who visited our emergency room with complaints of thoracic trauma were analyzed retrospectively. All the patients had thoracic MDCT performed and the three-dimensional reconstructive images were taken. The fractures were confirmed by axial CT, the clinical information, whole body bone scanning and the multiplanar reformation images. Plain x-ray images were analyzed by the fractured sites in a blind comparison of two radiologists' readings, and then that finding was compared with the axial CT scans and the three-dimensional reconstructive images. The fracture sites were rib (n 68), sternum (n = 14), clavicle (n = 6), scapula (n = 3), spine (n = 5) and combined fractures (n = 14). Plain x-ray and axial CT scans had a correspondency of 0.555 for the rib fractures. Axial CT scans and the three-dimensional reconstructive images had a correspondency of .952. For sternal fractures, those values were 0.692 and 0.928, respectively. The axial CT scans and three-dimensional reconstructive images showed sensitivities of 94% and 91% for rib and other fractures, respectively, and 93% and 100% for sternal fracture, respectively. Three-dimensional reconstructive image had an especially high sensitivity for the diagnosis of sternal fracture. While evaluating thoracic trauma at the emergency room, the three-dimensional reconstructive image was useful to easily diagnose the extent of fracture and it was very sensitive for detecting sternal fracture

  9. Three-dimensional accuracy of plastic transfer impression copings for three implant systems.

    Science.gov (United States)

    Teo, Juin Wei; Tan, Keson B; Nicholls, Jack I; Wong, Keng Mun; Uy, Joanne

    2014-01-01

    The purpose of this study was to compare the three-dimensional accuracy of indirect plastic impression copings and direct implant-level impression copings from three implant systems (Nobel Biocare [NB], Biomet 3i [3i], and Straumann [STR]) at three interimplant buccolingual angulations (0, 8, and 15 degrees). Two-implant master models were used to simulate a three-unit implant fixed partial denture. Test models were made from Impregum impressions using direct implant-level impression copings (DR). Abutments were then connected to the master models for impressions using the plastic impression copings (INDR) at three different angulations for a total of 18 test groups (n = 5 in each group). A coordinate measuring machine was used to measure linear distortions, three-dimensional (3D) distortions, angular distortions, and absolute angular distortions between the master and test models. Three-way analysis of variance showed that the implant system had a significant effect on 3D distortions and absolute angular distortions in the x- and y-axes. Interimplant angulation had a significant effect on 3D distortions and absolute angular distortions in the y-axis. Impression technique had a significant effect on absolute angular distortions in the y-axis. With DR, the NB and 3i systems were not significantly different. With INDR, 3i appeared to have less distortion than the other systems. Interimplant angulations did not significantly affect the accuracy of NBDR, 3iINDR, and STRINDR. The accuracy of INDR and DR was comparable at all interimplant angulations for 3i and STR. For NB, INDR was comparable to DR at 0 and 8 degrees but was less accurate at 15 degrees. Three-dimensional accuracy of implant impressions varied with implant system, interimplant angulation, and impression technique.

  10. Phase Diagrams of Three-Dimensional Anderson and Quantum Percolation Models Using Deep Three-Dimensional Convolutional Neural Network

    Science.gov (United States)

    Mano, Tomohiro; Ohtsuki, Tomi

    2017-11-01

    The three-dimensional Anderson model is a well-studied model of disordered electron systems that shows the delocalization-localization transition. As in our previous papers on two- and three-dimensional (2D, 3D) quantum phase transitions [J. Phys. Soc. Jpn. 85, 123706 (2016), 86, 044708 (2017)], we used an image recognition algorithm based on a multilayered convolutional neural network. However, in contrast to previous papers in which 2D image recognition was used, we applied 3D image recognition to analyze entire 3D wave functions. We show that a full phase diagram of the disorder-energy plane is obtained once the 3D convolutional neural network has been trained at the band center. We further demonstrate that the full phase diagram for 3D quantum bond and site percolations can be drawn by training the 3D Anderson model at the band center.

  11. Locally challenging osteo- and chondrogenic tumors of the axial skeleton: results of combined proton and photon radiation therapy using three-dimensional treatment planning

    Energy Technology Data Exchange (ETDEWEB)

    Hug, Eugen B; Fitzek, Markus M; Liebsch, Norbert J; Munzenrider, John E

    1995-02-01

    Purpose: Tumors of the axial skeleton are at high risk for local failure. Total surgical resection is rarely possible. Critical normal tissues limit the efficacy of conventional photon therapy. This study reviews our experience of using combined high dose proton and photon radiation therapy following three-dimensional (3D) treatment planning. Methods and Materials: Between December 1980 and September 1992, 47 patients were treated at the Massachusetts General Hospital and Harvard Cyclotron Laboratory for primary or recurrent chordomas and chondrosarcomas (group 1, 20 patients), osteogenic sarcomas (group 2, 15 patients) and giant cell tumors, osteo- or chondroblastomas (group 3, 12 patients). Radiation treatment was given postoperatively in 23 patients, pre- and postoperatively in 17 patients, and 7 patients received radiation therapy as definitive treatment modality following biopsy only. The proton radiation component was delivered using a 160 MeV proton beam and the photon component using megavoltage photons up to 23 MV energy with 1.8-2.0 Cobalt Gray Equivalent (CGE) per fraction, once a day. Total external beam target dose ranged from 55.3 CGE to 82.0 CGE with mean target doses of 73.9 CGE (group 1), 69.8 CGE (group 2), and 61.8 CGE (group 3). Results: Group 1 (chordoma and chondrosarcoma): Five of 14 patients (36%) with chordoma recurred locally, and 2 out of 5 patients developed distant metastasis, resulting in 1 death from disease. A trend for improved local control was noted for primary vs. recurrent tumors, target doses > 77 CGE and gross total resection. All patients with chondrosarcoma achieved and maintained local control and disease-free status. Five-year actuarial local control and overall survival rates were 53% and 50% for chordomas and 100% and 100% for chondrosarcomas, respectively. Group 2 (osteogenic sarcoma): Three of 15 patients (20%) never achieved local control and died within 6 months of completion of radiation treatment. Only 1 out of 12

  12. On Unsteady Three-Dimensional Axisymmetric MHD Nanofluid Flow with Entropy Generation and Thermo-Diffusion Effects on a Non-Linear Stretching Sheet

    Directory of Open Access Journals (Sweden)

    Mohammed Almakki

    2017-07-01

    Full Text Available The entropy generation in unsteady three-dimensional axisymmetric magnetohydrodynamics (MHD nanofluid flow over a non-linearly stretching sheet is investigated. The flow is subject to thermal radiation and a chemical reaction. The conservation equations are solved using the spectral quasi-linearization method. The novelty of the work is in the study of entropy generation in three-dimensional axisymmetric MHD nanofluid and the choice of the spectral quasi-linearization method as the solution method. The effects of Brownian motion and thermophoresis are also taken into account. The nanofluid particle volume fraction on the boundary is passively controlled. The results show that as the Hartmann number increases, both the Nusselt number and the Sherwood number decrease, whereas the skin friction increases. It is further shown that an increase in the thermal radiation parameter corresponds to a decrease in the Nusselt number. Moreover, entropy generation increases with respect to some physical parameters.

  13. Three dimensional force prediction in a model linear brushless dc motor

    Energy Technology Data Exchange (ETDEWEB)

    Moghani, J.S.; Eastham, J.F.; Akmese, R.; Hill-Cottingham, R.J. (Univ. of Bath (United Kingdom). School of Electronic and Electric Engineering)

    1994-11-01

    Practical results are presented for the three axes forces produced on the primary of a linear brushless dc machine which is supplied from a three-phase delta-modulated inverter. Conditions of both lateral alignment and lateral displacement are considered. Finite element analysis using both two and three dimensional modeling is compared with the practical results. It is shown that a modified two dimensional model is adequate, where it can be used, in the aligned position and that the full three dimensional method gives good results when the machine is axially misaligned.

  14. Radiation effects on two-dimensional materials

    Energy Technology Data Exchange (ETDEWEB)

    Walker, R.C. II; Robinson, J.A. [Department of Materials Science, Penn State, University Park, PA (United States); Center for Two-Dimensional Layered Materials, Penn State, University Park, PA (United States); Shi, T. [Department of Mechanical and Nuclear Engineering, Penn State, University Park, PA (United States); Department of Nuclear Engineering and Radiological Sciences, University of Michigan, Ann Arbor, MI (United States); Silva, E.C. [GlobalFoundries, Malta, NY (United States); Jovanovic, I. [Department of Nuclear Engineering and Radiological Sciences, University of Michigan, Ann Arbor, MI (United States)

    2016-12-15

    The effects of electromagnetic and particle irradiation on two-dimensional materials (2DMs) are discussed in this review. Radiation creates defects that impact the structure and electronic performance of materials. Determining the impact of these defects is important for developing 2DM-based devices for use in high-radiation environments, such as space or nuclear reactors. As such, most experimental studies have been focused on determining total ionizing dose damage to 2DMs and devices. Total dose experiments using X-rays, gamma rays, electrons, protons, and heavy ions are summarized in this review. We briefly discuss the possibility of investigating single event effects in 2DMs based on initial ion beam irradiation experiments and the development of 2DM-based integrated circuits. Additionally, beneficial uses of irradiation such as ion implantation to dope materials or electron-beam and helium-beam etching to shape materials have begun to be used on 2DMs and are reviewed as well. For non-ionizing radiation, such as low-energy photons, we review the literature on 2DM-based photo-detection from terahertz to UV. The majority of photo-detecting devices operate in the visible and UV range, and for this reason they are the focus of this review. However, we review the progress in developing 2DMs for detecting infrared and terahertz radiation. (copyright 2016 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  15. Optimization of three-dimensional micropost microcavities for cavity quantum electrodynamics

    International Nuclear Information System (INIS)

    Vuckovic, Jelena; Pelton, Matthew; Scherer, Axel; Yamamoto, Yoshihisa

    2002-01-01

    This paper presents a detailed analysis, based on the first-principles finite-difference time-domain method, of the resonant frequency, quality factor (Q), mode volume (V), and radiation pattern of the fundamental (HE 11 ) mode in a three-dimensional distributed-Bragg-reflector (DBR) micropost microcavity. By treating this structure as a one-dimensional cylindrical photonic crystal containing a single defect, we are able to push the limits of Q/V beyond those achievable by standard micropost designs, based on the simple rules established for planar DBR microcavities. We show that some of the rules that work well for designing large-diameter microposts (e.g., high-refractive-index contrast) fail to provide high-quality cavities with small diameters. By tuning the thicknesses of mirror layers and the spacer, the number of mirror pairs, the refractive indices of high- and low-refractive index regions, and the cavity diameter, we are able to achieve Q as high as 10 4 , together with a mode volume of 1.6 cubic wavelengths of light in the high-refractive-index material. The combination of high Q and small V makes these structures promising candidates for the observation of such cavity-quantum-electrodynamics phenomena as strong coupling between a quantum dot and the cavity field, and single-quantum-dot lasing

  16. Visual Interpretation with Three-Dimensional Annotations (VITA): three-dimensional image interpretation tool for radiological reporting.

    Science.gov (United States)

    Roy, Sharmili; Brown, Michael S; Shih, George L

    2014-02-01

    This paper introduces a software framework called Visual Interpretation with Three-Dimensional Annotations (VITA) that is able to automatically generate three-dimensional (3D) visual summaries based on radiological annotations made during routine exam reporting. VITA summaries are in the form of rotating 3D volumes where radiological annotations are highlighted to place important clinical observations into a 3D context. The rendered volume is produced as a Digital Imaging and Communications in Medicine (DICOM) object and is automatically added to the study for archival in Picture Archiving and Communication System (PACS). In addition, a video summary (e.g., MPEG4) can be generated for sharing with patients and for situations where DICOM viewers are not readily available to referring physicians. The current version of VITA is compatible with ClearCanvas; however, VITA can work with any PACS workstation that has a structured annotation implementation (e.g., Extendible Markup Language, Health Level 7, Annotation and Image Markup) and is able to seamlessly integrate into the existing reporting workflow. In a survey with referring physicians, the vast majority strongly agreed that 3D visual summaries improve the communication of the radiologists' reports and aid communication with patients.

  17. Variations in gene and protein expression in canine chondrodystrophic nucleus pulposus cells following long-term three-dimensional culture.

    Directory of Open Access Journals (Sweden)

    Munetaka Iwata

    Full Text Available Intervertebral disc (IVD degeneration greatly affects quality of life. The nucleus pulposus (NP of chondrodystrophic dog breeds (CDBs is similar to the human NP, because the cells disappear with age and are replaced by fibrochondrocyte-like cells. However, because IVD develops as early as within the first year of life, we used canines as a model to investigate in vitro the mechanisms underlying IVD degeneration. Specifically, we evaluated the potential of a three-dimensional (3D culture of healthy NP as an in vitro model system to investigate the mechanisms of IVD degeneration. Agarose hydrogels were populated with healthy NP cells from beagles after performing magnetic resonance imaging, and mRNA expression profiles and pericellular extracellular matrix (ECM protein distribution were determined. After 25 days of 3D culture, there was a tendency for redifferentiation into the native NP phenotype, and mRNA levels of Col2A1, COMP, and CK18 were not significantly different from those of freshly isolated cells. Our findings suggest that long-term 3D culture promoted chondrodystrophic NP redifferentiation through reconstruction of the pericellular microenvironment. Further, lipopolysaccharide (LPS induced expression of TNF-α, MMP3, MMP13, VEGF, and PGES mRNA in the 3D cultures, creating a molecular milieu that mimics that of degenerated NP. These results suggest that this in vitro model represents a reliable and cost-effective tool for evaluating new therapies for disc degeneration.

  18. Three-dimensional Simulation of Backward Raman Amplification

    International Nuclear Information System (INIS)

    Balakin, A.A.; Fraiman, G.M.; Fisch, N.J.

    2005-01-01

    Three-dimensional (3-D) simulations for the Backward Raman Amplification (BRA) are presented. The images illustrate the effects of pump depletion, pulse diffraction, non-homogeneous plasma density, and plasma ionization

  19. Star-disc interaction in galactic nuclei: formation of a central stellar disc

    Science.gov (United States)

    Panamarev, Taras; Shukirgaliyev, Bekdaulet; Meiron, Yohai; Berczik, Peter; Just, Andreas; Spurzem, Rainer; Omarov, Chingis; Vilkoviskij, Emmanuil

    2018-05-01

    We perform high-resolution direct N-body simulations to study the effect of an accretion disc on stellar dynamics in an active galactic nucleus (AGN). We show that the interaction of the nuclear stellar cluster (NSC) with the gaseous accretion disc (AD) leads to formation of a stellar disc in the central part of the NSC. The accretion of stars from the stellar disc on to the super-massive black hole is balanced by the capture of stars from the NSC into the stellar disc, yielding a stationary density profile. We derive the migration time through the AD to be 3 per cent of the half-mass relaxation time of the NSC. The mass and size of the stellar disc are 0.7 per cent of the mass and 5 per cent of the influence radius of the super-massive black hole. An AD lifetime shorter than the migration time would result in a less massive nuclear stellar disc. The detection of such a stellar disc could point to past activity of the hosting galactic nucleus.

  20. Three-dimensional simulations of an XUV free-electron laser

    International Nuclear Information System (INIS)

    Goldstein, J.C.; McVey, B.D.; Newnam, B.E.

    1985-01-01

    Operation of free-electron lasers (FEL) at long optical wavelengths (greater than or equal to 600 nm) has now been successfully demonstrated at several laboratories. To operate an FEL at shorter wavelengths imposes constraints on the brightness of the electron beam which are difficult to achieve. Until recently, it was perceived that only an electron storage ring could satisfy these beam requirements. However, our previous 1-D theoretical calculations revealed that modest improvements in the emittance available from rf-linear accelerators would be sufficient to allow operation of an FEL in the XUV spectral range (greater than or equal to 50 nm). We shall present new theoretical results for the design of a linac-driven XUV FEL derived from an improved simulation model. The model is fully three-dimensional in its treatment of the undulator magnetic field, the optical radiation field, and the motion of electrons in a finite-emittance beam. Furthermore, the model computes self-consistently the motion of the electrons and the amplification, diffraction, and the refraction of the light within the undulator magnet. Propagation of the optical beam and reflection at the mirrors of the optical resonator are incorporated in the model so that a complete laser oscillator solution can be generated. The computed performance parameters of a particular XUV FEL oscillator design will be compared with the output of synchrotron radiation sources. 26 refs., 8 figs

  1. Three dimensional transport model for toroidal plasmas

    International Nuclear Information System (INIS)

    Copenhauer, C.

    1980-12-01

    A nonlinear MHD model, developed for three-dimensional toroidal geometries (asymmetric) and for high β (β approximately epsilon), is used as a basis for a three-dimensional transport model. Since inertia terms are needed in describing evolving magnetic islands, the model can calculate transport, both in the transient phase before nonlinear saturation of magnetic islands and afterwards on the resistive time scale. In the β approximately epsilon ordering, the plasma does not have sufficient energy to compress the parallel magnetic field, which allows the Alfven wave to be eliminated in the reduced nonlinear equations, and the model then follows the slower time scales. The resulting perpendicular and parallel plasma drift velocities can be identified with those of guiding center theory

  2. Three dimensional imaging in cardiac nuclear medicine

    International Nuclear Information System (INIS)

    Torizuka, Kanji; Ishii, Yasushi; Yonekura, Yoshiharu; Yamamoto, Kazutaka; Tamaki, Takeyoshi

    1981-01-01

    Methods to obtain three dimensional images of the heart were reviewed. Gated three dimensional display reconstructed from images using bidirectional collimator, was a useful method to detect akinesis of the heart wall. Tomographic observation of the heart can be carried out by a pinhole collimator to image ischemia with high sensitivity. However the focusing plane must be carefully selected to prevent false positives. In the case of emission CT (ECT), utilization of positron emitters gave a quantitative image without correction, whereas single photon ECT needed the correction due to the absorption of γ-ray. Though the reliability of the images by ECT was high, the time required for data acquisition was much longer than that by a 7 pinhole or bidirectional collimator. (Nakanishi, T.)

  3. [Three-dimensional computer aided design for individualized post-and-core restoration].

    Science.gov (United States)

    Gu, Xiao-yu; Wang, Ya-ping; Wang, Yong; Lü, Pei-jun

    2009-10-01

    To develop a method of three-dimensional computer aided design (CAD) of post-and-core restoration. Two plaster casts with extracted natural teeth were used in this study. The extracted teeth were prepared and scanned using tomography method to obtain three-dimensional digitalized models. According to the basic rules of post-and-core design, posts, cores and cavity surfaces of the teeth were designed using the tools for processing point clouds, curves and surfaces on the forward engineering software of Tanglong prosthodontic system. Then three-dimensional figures of the final restorations were corrected according to the configurations of anterior teeth, premolars and molars respectively. Computer aided design of 14 post-and-core restorations were finished, and good fitness between the restoration and the three-dimensional digital models were obtained. Appropriate retention forms and enough spaces for the full crown restorations can be obtained through this method. The CAD of three-dimensional figures of the post-and-core restorations can fulfill clinical requirements. Therefore they can be used in computer-aided manufacture (CAM) of post-and-core restorations.

  4. Finite element method for radiation heat transfer in multi-dimensional graded index medium

    International Nuclear Information System (INIS)

    Liu, L.H.; Zhang, L.; Tan, H.P.

    2006-01-01

    In graded index medium, ray goes along a curved path determined by Fermat principle, and curved ray-tracing is very difficult and complex. To avoid the complicated and time-consuming computation of curved ray trajectories, a finite element method based on discrete ordinate equation is developed to solve the radiative transfer problem in a multi-dimensional semitransparent graded index medium. Two particular test problems of radiative transfer are taken as examples to verify this finite element method. The predicted dimensionless net radiative heat fluxes are determined by the proposed method and compared with the results obtained by finite volume method. The results show that the finite element method presented in this paper has a good accuracy in solving the multi-dimensional radiative transfer problem in semitransparent graded index medium

  5. Human disc cells in monolayer vs 3D culture: cell shape, division and matrix formation

    Directory of Open Access Journals (Sweden)

    Hanley Edward N

    2000-10-01

    Full Text Available Abstract Background The relationship between cell shape, proliferation, and extracellular matrix (ECM production, important aspects of cell behavior, is examined in a little-studied cell type, the human annulus cell from the intervertebral disc, during monolayer vs three-dimensional (3D culture. Results Three experimental studies showed that cells respond specifically to culture microenvironments by changes in cell shape, mitosis and ECM production: 1 Cell passages showed extensive immunohistochemical evidence of Type I and II collagens only in 3D culture. Chondroitin sulfate and keratan sulfate were abundant in both monolayer and 3D cultures. 2 Cells showed significantly greater proliferation in monolayer in the presence of platelet-derived growth factor compared to cells in 3D. 3 Cells on Matrigel™-coated monolayer substrates became rounded and formed nodular colonies, a finding absent during monolayer growth. Conclusions The cell's in vivo interactions with the ECM can regulate shape, gene expression and other cell functions. The shape of the annulus cell changes markedly during life: the young, healthy disc contains spindle shaped cells and abundant collagen. With aging and degeneration, many cells assume a strikingly different appearance, become rounded and are surrounded by unusual accumulations of ECM products. In vitro manipulation of disc cells provides an experimental window for testing how disc cells from given individuals respond when they are grown in environments which direct cells to have either spindle- or rounded-shapes. In vitro assessment of the response of such cells to platelet-derived growth factor and to Matrigel™ showed a continued influence of cell shape even in the presence of a growth factor stimulus. These findings contribute new information to the important issue of the influence of cell shape on cell behavior.

  6. Improved design of three-dimensional lens for low concentrator PV modules; Teishukogata taiyo denchiyo sanjigen lens no koseinoka ni kansuru kenkyu

    Energy Technology Data Exchange (ETDEWEB)

    Goma, S; Yoshioka, K; Saito, T [Tokyo Univ. of Agriculture and Technology, Tokyo (Japan)

    1997-11-25

    Attention is paid to reduction in area required for solar cells by solar concentration as a means of solving cost limits of solar cells and unstable supply of Si materials. Low concentration solar cells are effective from the aspects of utilization of scattered light and unnecessary ray tracing. The optical concentration ratio was calculated of three-dimensional lens having design values of various north/south and east/west direction allowable incidence half angles. The three-dimensional lens are designed by cutting a rectangular parallelepiped by the two-dimensional composite elliptical plane designed by various allowable incidence half angles from two directions of north/south and east/west. Using Perez`s sky solar radiation models and meteorological data HASP, calculated were the annual accumulated global radiation ratio on an inclined surface and the optical efficiency. Calculated were the solar cell area ratio and solar concentration area ratio of the concentration type to obtain solar radiation the same as that of the planar type. From the optimization calculation, it was found that lens are optimal which have design values of north/south and east/west direction allowable incidence half angles of 30-70deg. The solar cell area ratio is 57% and the solar concentration area ratio is 1.2 times. It was found that by making the module area 1.2 times, more than 40% of the solar cells used can be saved. 5 refs., 8 figs.

  7. Three-dimensional propagation in near-field tomographic X-ray phase retrieval

    International Nuclear Information System (INIS)

    Ruhlandt, Aike; Salditt, Tim

    2016-01-01

    An extension of phase retrieval algorithms for near-field X-ray (propagation) imaging to three dimensions is presented, enhancing the quality of the reconstruction by exploiting previously unused three-dimensional consistency constraints. This paper presents an extension of phase retrieval algorithms for near-field X-ray (propagation) imaging to three dimensions, enhancing the quality of the reconstruction by exploiting previously unused three-dimensional consistency constraints. The approach is based on a novel three-dimensional propagator and is derived for the case of optically weak objects. It can be easily implemented in current phase retrieval architectures, is computationally efficient and reduces the need for restrictive prior assumptions, resulting in superior reconstruction quality

  8. Three dimensional reconstruction of tomographic images of the retina

    International Nuclear Information System (INIS)

    Glittenberg, C.; Zeiler, F.; Falkner, C.; Binder, S.; Povazay, B.; Hermann, B.; Drexler, W.

    2007-01-01

    The development of a new display system for the three-dimensional visualization of tomographic images in ophthalmology. Specifically, a system that can use stacks of B-mode scans from an ultrahigh resolution optical tomography examination to vividly display retinal specimens as three-dimensional objects. Several subroutines were programmed in the rendering and raytracing program Cinema 4D XL 9.102 Studio Bundle (Maxon Computer Inc., Friedrichsburg, Germany), which could process stacks of tomographic scans into three-dimensional objects. Ultrahigh resolution optical coherence tomography examinations were performed on patients with various retinal pathologies and post processed with the subroutines that had been designed. All ultrahigh resolution optical coherence tomographies were performed with a titanium: sapphire based ultra broad bandwidth (160 nm) femtosecond laser system (INTEGRAL, Femtolasers Productions GmbH. Vienna Austria) with an axial resolution of 3 μm. A new three dimensional display system for tomographic images in ophthalmology was developed, which allows a highly vivid display of physiological and pathological structures of the retina. The system also distinguishes itself through its high interactivity and adaptability. This new display system allows the visualization of physiological and pathological structures of the retina in a new way, which will give us new insight into their morphology and development. (author) [de

  9. Clinical significance of three-dimensional sonohysterography

    International Nuclear Information System (INIS)

    Lee, Eun Hye; Lee, Mi Hwa; Lee, Chan; Kim, Jong Wook; Shin, Myung Choel

    1999-01-01

    To evaluate the usefulness of three dimensional sonohysterography (3D SHG) in the evaluation of uterine endometrial and submucosal lesions in comparison with conventional two-dimensional sonohysterography (2D SHG). Our series consisted of 26 patients (mean aged 41 years) who complained of uterine bleeding, menorrhagia, or dysmenorrhea. 2D SHG was performed, and then 3D SHG was done after the volume mode was switched on. Simultaneous display of three perpendicular two-dimensional planes and surface rendering of findings on particular section were obtained. We analyzed whether the endometrium was thickened or not, and the location, size, shape, echogenicity, posterior shadowing, and echogenic rim of the focal lesion. The results were compared with the pathologic findings or MRI. There were submucosal myomas (n=12), intramural myomas (n=2), endometrial polyps (n=7), placental polyp (n=1), and normal endometrial cavities (n=4) on SHG. Nineteen cases were confirmed by pathologic findings or MRI. The results were correlated in 89% (17/19) of the cases. We misdiagnosed 2 cases: focal endometrial hyperplasia and choriocarcinoma were misdiagnosed as endometrial polyp and placental polyp, respectively. Imaging diagnoses were same in the techniques. Comparing with 2D SHG, 3D SHG provided a subjective display of pathologic findings and an additional information about spatial relationship between focal lesion and surroundings.

  10. Clinical significance of three-dimensional sonohysterography

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Eun Hye; Lee, Mi Hwa; Lee, Chan; Kim, Jong Wook; Shin, Myung Choel [Pochon Cha University College of Medicine, Pochon (Korea, Republic of)

    1999-12-15

    To evaluate the usefulness of three dimensional sonohysterography (3D SHG) in the evaluation of uterine endometrial and submucosal lesions in comparison with conventional two-dimensional sonohysterography (2D SHG). Our series consisted of 26 patients (mean aged 41 years) who complained of uterine bleeding, menorrhagia, or dysmenorrhea. 2D SHG was performed, and then 3D SHG was done after the volume mode was switched on. Simultaneous display of three perpendicular two-dimensional planes and surface rendering of findings on particular section were obtained. We analyzed whether the endometrium was thickened or not, and the location, size, shape, echogenicity, posterior shadowing, and echogenic rim of the focal lesion. The results were compared with the pathologic findings or MRI. There were submucosal myomas (n=12), intramural myomas (n=2), endometrial polyps (n=7), placental polyp (n=1), and normal endometrial cavities (n=4) on SHG. Nineteen cases were confirmed by pathologic findings or MRI. The results were correlated in 89% (17/19) of the cases. We misdiagnosed 2 cases: focal endometrial hyperplasia and choriocarcinoma were misdiagnosed as endometrial polyp and placental polyp, respectively. Imaging diagnoses were same in the techniques. Comparing with 2D SHG, 3D SHG provided a subjective display of pathologic findings and an additional information about spatial relationship between focal lesion and surroundings.

  11. Prognostic value of three-dimensional ultrasound for fetal hydronephrosis

    Science.gov (United States)

    WANG, JUNMEI; YING, WEIWEN; TANG, DAXING; YANG, LIMING; LIU, DONGSHENG; LIU, YUANHUI; PAN, JIAOE; XIE, XING

    2015-01-01

    The present study evaluated the prognostic value of three-dimensional ultrasound for fetal hydronephrosis. Pregnant females with fetal hydronephrosis were enrolled and a novel three-dimensional ultrasound indicator, renal parenchymal volume/kidney volume, was introduced to predict the postnatal prognosis of fetal hydronephrosis in comparison with commonly used ultrasound indicators. All ultrasound indicators of fetal hydronephrosis could predict whether postnatal surgery was required for fetal hydronephrosis; however, the predictive performance of renal parenchymal volume/kidney volume measurements as an individual indicator was the highest. In conclusion, ultrasound is important in predicting whether postnatal surgery is required for fetal hydronephrosis, and the three-dimensional ultrasound indicator renal parenchymal volume/kidney volume has a high predictive performance. Furthermore, the majority of cases of fetal hydronephrosis spontaneously regress subsequent to birth, and the regression time is closely associated with ultrasound indicators. PMID:25667626

  12. Imaging unsteady three-dimensional transport phenomena

    Indian Academy of Sciences (India)

    2014-01-05

    Jan 5, 2014 ... The image data can be jointly analysed with the physical laws governing transport and principles of image formation. Hence, with the experiment suitably carried out, three-dimensional physical domains with unsteady processes can be accommodated. Optical methods promise to breach the holy grail of ...

  13. Usefulness Of Three-Dimensional Printing Models for Patients with Stoma Construction

    OpenAIRE

    Tominaga, Tetsuro; Takagi, Katsunori; Takeshita, Hiroaki; Miyamoto, Tomo; Shimoda, Kozue; Matsuo, Ayano; Matsumoto, Keitaro; Hidaka, Shigekazu; Yamasaki, Naoya; Sawai, Terumitsu; Nagayasu, Takeshi

    2016-01-01

    The use of patient-specific organ models in three-dimensional printing systems could be helpful for the education of patients and medical students. The aim of this study was to clarify whether the use of patient-specific stoma models is helpful for patient education. From January 2014 to September 2014, 5 patients who underwent colorectal surgery and for whom a temporary or permanent stoma had been created were involved in this study. Three-dimensional stoma models and three-dimensional face ...

  14. Loop expansion in massless three-dimensional QED

    International Nuclear Information System (INIS)

    Guendelman, E.I.; Radulovic, Z.M.

    1983-01-01

    It is shown how the loop expansion in massless three-dimensional QED can be made finite, up to three loops, by absorbing the infrared divergences in a gauge-fixing term. The same method removes leading and first subleading singularities to all orders of perturbation theory, and all singularities of the fermion self-energy to four loops

  15. Comparison of two three-dimensional cephalometric analysis computer software

    OpenAIRE

    Sawchuk, Dena; Alhadlaq, Adel; Alkhadra, Thamer; Carlyle, Terry D; Kusnoto, Budi; El-Bialy, Tarek

    2014-01-01

    Background: Three-dimensional cephalometric analyses are getting more attraction in orthodontics. The aim of this study was to compare two softwares to evaluate three-dimensional cephalometric analyses of orthodontic treatment outcomes. Materials and Methods: Twenty cone beam computed tomography images were obtained using i-CAT® imaging system from patient's records as part of their regular orthodontic records. The images were analyzed using InVivoDental5.0 (Anatomage Inc.) and 3DCeph™ (Unive...

  16. Three-dimensional transesophageal echocardiography of the atrial septal defects

    Directory of Open Access Journals (Sweden)

    Romero-Cárdenas Ángel

    2008-07-01

    Full Text Available Abstract Transesophageal echocardiography has advantages over transthoracic technique in defining morphology of atrial structures. Even though real time three-dimensional echocardiographic imaging is a reality, the off-line reconstruction technique usually allows to obtain higher spatial resolution images. The purpose of this study was to explore the accuracy of off-line three-dimensional transesophageal echocardiography in a spectrum of atrial septal defects by comparing them with representative anatomic specimens.

  17. Symmetries, integrals, and three-dimensional reductions of Plebanski's second heavenly equation

    International Nuclear Information System (INIS)

    Neyzi, F.; Sheftel, M. B.; Yazici, D.

    2007-01-01

    We study symmetries and conservation laws for Plebanski's second heavenly equation written as a first-order nonlinear evolutionary system which admits a multi-Hamiltonian structure. We construct an optimal system of one-dimensional subalgebras and all inequivalent three-dimensional symmetry reductions of the original four-dimensional system. We consider these two-component evolutionary systems in three dimensions as natural candidates for integrable systems

  18. Upper bound on the capacity of constrained three-dimensional codes

    DEFF Research Database (Denmark)

    Forchhammer, Søren

    2000-01-01

    An upper bound on the capacity of constrained three-dimensional codes is presented. The bound for two-dimensional codes of Calkin and Wilf (see SIAM Journal of Discrete Mathematics, vol.11, no.1, p.54-60, 1998) was extended to three dimensions by Nagy and Zeger. Both bounds apply to first order s...

  19. Teaching veterinary obstetrics using three-dimensional animation technology.

    Science.gov (United States)

    Scherzer, Jakob; Buchanan, M Flint; Moore, James N; White, Susan L

    2010-01-01

    In this three-year study, test scores for students taught veterinary obstetrics in a classroom setting with either traditional media (photographs, text, and two-dimensional graphical presentations) were compared with those for students taught by incorporating three-dimensional (3D) media (linear animations and interactive QuickTime Virtual Reality models) into the classroom lectures. Incorporation of the 3D animations and interactive models significantly increased students' scores on essay questions designed to assess their comprehension of the subject matter. This approach to education may help to better prepare students for dealing with obstetrical cases during their final clinical year and after graduation.

  20. Three-dimensional wax patterning of paper fluidic devices.

    Science.gov (United States)

    Renault, Christophe; Koehne, Jessica; Ricco, Antonio J; Crooks, Richard M

    2014-06-17

    In this paper we describe a method for three-dimensional wax patterning of microfluidic paper-based analytical devices (μPADs). The method is rooted in the fundamental details of wax transport in paper and provides a simple way to fabricate complex channel architectures such as hemichannels and fully enclosed channels. We show that three-dimensional μPADs can be fabricated with half as much paper by using hemichannels rather than ordinary open channels. We also provide evidence that fully enclosed channels are efficiently isolated from the exterior environment, decreasing contamination risks, simplifying the handling of the device, and slowing evaporation of solvents.