WorldWideScience

Sample records for thierry emonet yale

  1. Thierry Lagrange: A transparent, service-oriented approach to finance

    CERN Multimedia

    2009-01-01

    The motto for the new Finance and Purchasing Department Head, Thierry Lagrange, is "strengthening services for users". With a head-count of around sixty, the Finance and Purchasing Department is small compared to the large technical departments. But its work is crucial and supports all the Laboratory’s activities. The FP Department manages the Organization’s financial resources and commitments, checking that resources match expenses, that sufficient cash is available, that contracts are concluded on the best possible terms - in short, that monies are available and properly managed. In these lean times, this delicate balancing act requires the skills of an insider, someone who knows the Organization like the back of his hand. Thierry Lagrange, recently appointed Head of Finance and Purchasing, has spent most of his career at CERN, and the past five years as Deputy Head of the Finance Department. Nobody knows the subtleties and p...

  2. Le temple-mémorial de Château-Thierry : approche monographique

    Directory of Open Access Journals (Sweden)

    Aline Magnien

    2005-09-01

    Full Text Available Le temple-mémorial de Château-Thierry, inauguré en 1924 est réalisé par deux architectes : Paul-Philippe Cret et Achille-Henri Chauquet, L’édifice est décoré d’un vitrail-tableau intitulé La Fayette nous voilà ! représentant La Fayette accueillant le général Pershing et de verrières ornées de scènes tirées des Paraboles de l’artiste suisse Eugène Burnand par son fils David Burnand. La chaire et le mobilier ont été offerts par des paroisses américaines en souvenir des soldats tombés au front. Par son architecture, son mobilier et les circonstances de la commande, le temple de Château-Thierry méritait une étude.The American memorial church of Château-Thierry, dedicated in 1924 has been built by two architects, Paul-Philippe Cret and Achille-Henri Chauquet. The church is adorned by a stained glass church window showing La Fayette welcoming Pershing and by some others stained glasses representing parables by David Burnand from sketches of his father Eugène Burnand. American churches supplied the pulpit and other furniture to adorn the building in memory of the soldiers died in the battle front. By its architecture, its furniture and the circumstances of its edification, the memorial church of Château-Thierry deserves a study

  3. [Low urinary tract symptoms after Thierry's spatula delivery at first pregnancy].

    Science.gov (United States)

    Provansal, M; Bretelle, F; Bannier, M; Gamerre, M; Mazouni, C

    2007-11-01

    This study was undertaken to evaluate prevalence of low urinary tract symptoms (LUTS) after Thierry's spatula delivery at first pregnancy. A retrospective study of 236 primiparous with instrumental delivery or spontaneous delivery who had delivered from January 2001 to December 2002. Low urinary tract symptoms (LUTS) were evaluated one year after delivery with a questionnaire. Incidence of LUTS was compared depending on mode of delivery. Of the 236 patients included, 88.1% replied to the questionnaire, 106 who delivered spontaneously and 102 who underwent Thierry's spatula delivery. The incidence of urinary incontinence was similar after instrumental deliveries and after spontaneous vaginal deliveries (34.9 versus 24.5%, p=0.10). In univariate analysis, symptoms of urinary urgency and urinary frequency were higher after instrumental delivery than after spontaneous delivery, respectively, 34.9 versus 22.5%, p=0.049 and 19.8 versus 8.8%, p=0.03. After controlling for confounding factors, no difference in LUTS was observed between the two groups; the respective adjusted odds-ratios (95% IC) were 1,5 (0.8-3) for urinary incontinence, 1.7 (0.9-3.5) for urgency and 2.5 (0.9-6.3) for urinary frequency. One year after delivery, one third of patients will present urinary incontinence and more than 50% will complain of bladder instability symptoms. Compared to spontaneous vaginal delivery, the use of Thierry's spatulas at first pregnancy does not induce higher risk of LUTS.

  4. Megalomania del potere medico nei romanzi di Thierry Jonquet

    OpenAIRE

    Modenesi, Marco

    2016-01-01

    Thierry Jonquet (Paris, 1954-2009) specialized in thriller and crime novels with political and ethical themes such as reflections on how Medicine tend to exceed reasonable boundaries in the exercise of its powers. This essay focuses on the definition of some figures of doctors who show this dark side of Science and its multiple facets and it underlines also the condemnation that Jonquet inserts in his works, thanks to a deep renewal of detective story.

  5. The Yale plunger device

    Science.gov (United States)

    Cooper, J. R.; Krücken, R.; Beausang, C. W.; Casten, R. F.; Cata-Danil, G.; Liu, B.; Novak, J. R.; Zamfir, N. V.; Dewald, A.; Peusquens, R.; Tiesler, H.; von Brentano, P.; Barton, C.

    1998-04-01

    A new plunger device for lifetime experiments using the recoil distance method (RDM) is currently being constructed at Yale. This apparatus will be used for precision lifetime measurements on excited nuclear levels with lifetimes in the picosecond range. The new Yale plunger is designed for coincidence measurements with all major Ge arrays including Gammasphere. At Yale the plunger will be used in conjunction with the new YRAST Ball array (Yale Rochester Array for SpecTroscopy), as well as a variety of auxiliary detectors. It follows the new Cologne plunger in its layout and will employ a new LabView based control system for measurement and stabilization of the target to stopper foil distance. Such a feedback system is crucial for the planned precision lifetime measurements as well as for the measurement of very short level lifetimes around 1 ps. The conceptual design of the plunger as well as the new feedback system will be presented and the planned physics program will be discussed. This work is supported by DOE grant number DE-FG02-91ER40609

  6. The May Fourth Era at Yale-in-China, 1917-1921

    Directory of Open Access Journals (Sweden)

    Roy B. Campbell

    2008-10-01

    Full Text Available In 1906, Yale University founded a missionary middle school in Changsha, the capital city of China’s Hunan province. Long regarded by foreigners as China’s most conservative and anti-foreign province, Hunan, only five years previous, had been the last Chinese province to open its doors to foreign settlement. In this new and seemingly fertile field, the Americans of the Yale Foreign Missionary Society cultivated their middle school (Yali and, by 1916, had greatly expanded their presence by also opening a School of Nursing, a College of Arts and Sciences, and a Medical School. As with most missionary educational enterprises of this period, the primary objective of the Yale educational missionaries was to inculcate their students with Western Science and knowledge, and, most importantly, Christian values. With the anti-traditional and pro-democracy message of the New Culture movement that erupted amongst China’s youth both before and after the May Fourth incident of 1919, the Yale missionaries, like others, believed that their efforts were being fulfilled. However, after this rising student consciousness turned increasingly nationalistic and anti-foreign, the Yale missionaries eventually not only had to address its implications within the context of the greater missionary enterprise in China, but, even more importantly, had to confront its manifestations amongst the students in their own institution.

  7. Desdoblamiento y transformación de la identidad del personaje en / Mygale / de Thierry Jonquet

    Directory of Open Access Journals (Sweden)

    Carmen Camero Pérez

    2011-12-01

    Full Text Available From the studies of mythocritique and mythanalyse, this article proposes a study of Mygale, Thierry Jonquet’s story, where the stereotypes of the crime novel pass in the background for the benefit of the treatment of the problem of the metamorphosis, the transsexuality and the processing of the identity. The analysis of the structural constituents of the novel: characters, narrative authorities, speech, writing and mythical transposition (Pygmalion, reveal the interest of a novel strongly anchored in the contemporary reality which does not give up for all that the ancient imagination.

  8. 75 FR 3895 - Yale University, et al.;

    Science.gov (United States)

    2010-01-25

    ... DEPARTMENT OF COMMERCE International Trade Administration Yale University, et al.; Notice of Consolidated Decision on Applications for Duty-Free Entry of Electron Microscopes This is a decision consolidated pursuant to Section 6(c) of the Educational, Scientific, and Cultural Materials Importation Act of...

  9. An interdepartmental Ph.D. program in computational biology and bioinformatics: the Yale perspective.

    Science.gov (United States)

    Gerstein, Mark; Greenbaum, Dov; Cheung, Kei; Miller, Perry L

    2007-02-01

    Computational biology and bioinformatics (CBB), the terms often used interchangeably, represent a rapidly evolving biological discipline. With the clear potential for discovery and innovation, and the need to deal with the deluge of biological data, many academic institutions are committing significant resources to develop CBB research and training programs. Yale formally established an interdepartmental Ph.D. program in CBB in May 2003. This paper describes Yale's program, discussing the scope of the field, the program's goals and curriculum, as well as a number of issues that arose in implementing the program. (Further updated information is available from the program's website, www.cbb.yale.edu.)

  10. Um estadista na academia: Joaquim Nabuco na Universidade de Yale A Statesman in the Academy: Joaquim Nabuco at Yale

    Directory of Open Access Journals (Sweden)

    Kenneth David Jackson

    2008-04-01

    Full Text Available Um estudo das conferências acadêmicas que pronunciou Joaquim Nabuco, embaixador do Brasil em Washington, D.C., na Universidade de Yale e mais cinco universidades americanas durante o período 1908-1909. Nabuco volta a Camões como exemplo do amor a uma língua e uma cultura, das quais o Brasil seria a maior realização, e aproxima o espírito do nacionalismo das duas grandes nações como exemplos para a política do pan-americanismo da época.A study of the academic discourses of Joaquim Nabuco, Brazil’s ambassador in Washington, D.C., at Yale and five more universities from 1908-1909. Nabuco returns to Camões as the example of great love for a language and a culture, nobly represented by Brazil. Nabuco compares the two great nations as examples for the then current politics of pan-americanism.

  11. Before Mina Shaughnessy: Basic Writing at Yale, 1920-1960

    Science.gov (United States)

    Ritter, Kelly

    2008-01-01

    This article examines Yale's "Awkward Squad" of "basic" writers between 1920 and 1960. Using archival materials that illustrate the socioeconomic conditions of this early, "pre-Shaughnessy" site of remedial writing instruction, I argue for a re-definition of "basic" in composition studies using local, institutional values rather than generic…

  12. Reliability and validity of the Spanish version of the modified Yale Preoperative Anxiety Scale.

    Science.gov (United States)

    Jerez, C; Ullán, A M; Lázaro, J J

    2016-01-01

    To minimise preoperative stress and increase child cooperation during induction of anaesthesia is one of the most important perioperative objectives. The modified Yale Preoperative Anxiety Scale was developed to evaluate anxiety. The aim of this study was to translate into Spanish, and validate the psychometric properties of the Spanish version of this scale. The Spanish translation of the scale was performed following the World Health Organisation guidelines. During induction of anaesthesia, 81 children aged 2 to 12 years were recorded. Two observers evaluated the recordings independently. Content validity index of modified Yale Preoperative Anxiety Scale Spanish version was assessed. Weighted Kappa was calculated to measure interobserver agreement, and the Pearson correlation between the Induction Compliance Checklist and the modified Yale Preoperative Anxiety Scale was determined. The Spanish version obtained high content validity (0.91 to 0.98). Reliability analysis using weighted Kappa statistics revealed that interobserver agreement ranged from 0.54 to 0.75. Concurrent validity was high (r=0.94; P<.001). Validated assessment tools are needed to evaluate interventions to reduce child preoperative anxiety. The Spanish version of the modified Yale Preoperative Anxiety Scale evaluated in this study has shown good psychometric properties of reliability and validity. Copyright © 2015 Sociedad Española de Anestesiología, Reanimación y Terapéutica del Dolor. Publicado por Elsevier España, S.L.U. All rights reserved.

  13. Peru v. Yale: A Battle Rages over Machu Picchu

    Science.gov (United States)

    Glenn, David

    2009-01-01

    In early 1916, the legendary Yale University archaeologist Hiram Bingham III completed his third and final expedition in southern Peru. He shipped home 74 boxes of artifacts from Machu Picchu, a spectacular site in the Andes that is believed to have been the last major settlement of the Inca empire. Those boxes were supposed to be on temporary…

  14. Interactive radiopharmaceutical facility between Yale Medical Center and Brookhaven National Laboratory. Progress report, October 1976-June 1979

    Energy Technology Data Exchange (ETDEWEB)

    Gottschalk, A.

    1979-01-01

    DOE Contract No. EY-76-S-02-4078 was started in October 1976 to set up an investigative radiochemical facility at the Yale Medical Center which would bridge the gap between current investigation with radionuclides at the Yale School of Medicine and the facilities in the Chemistry Department at the Brookhaven National Laboratory. To facilitate these goals, Dr. Mathew L. Thakur was recruited who joined the Yale University faculty in March of 1977. This report briefly summarizes our research accomplishments through the end of June 1979. These can be broadly classified into three categories: (1) research using indium-111 labelled cellular blood components; (2) development of new radiopharmaceuticals; and (3) interaction with Dr. Alfred Wolf and colleagues in the Chemistry Department of Brookhaven National Laboratory.

  15. Interactive radiopharmaceutical facility between Yale Medical Center and Brookhaven National Laboratory. Progress report, October 1976-June 1979

    International Nuclear Information System (INIS)

    Gottschalk, A.

    1979-01-01

    DOE Contract No. EY-76-S-02-4078 was started in October 1976 to set up an investigative radiochemical facility at the Yale Medical Center which would bridge the gap between current investigation with radionuclides at the Yale School of Medicine and the facilities in the Chemistry Department at the Brookhaven National Laboratory. To facilitate these goals, Dr. Mathew L. Thakur was recruited who joined the Yale University faculty in March of 1977. This report briefly summarizes our research accomplishments through the end of June 1979. These can be broadly classified into three categories: (1) research using indium-111 labelled cellular blood components; (2) development of new radiopharmaceuticals; and (3) interaction with Dr. Alfred Wolf and colleagues in the Chemistry Department of Brookhaven National Laboratory

  16. Invited series of talks and lectures at Yale University (USA) on Rolf Nordahl's research

    DEFF Research Database (Denmark)

    Nordahl, Rolf

    2010-01-01

    in several topics. The lectures will address his innovative experiments on using methods from Film and Filmsound to inform research in Computer Games and Virtual Reality applications with real-life examples from the Natural Interactive Walking (NIW) project - a EU-funded project headed at Aalborg University......Rolf Nordahl , Medialogy in Copenhagen, will be giving an invited series of lectures at Yale University, Connecticut, USA in the last week of March, 2010. Rolf has been invited to give talks to Professors, research fellows, Ph.D.'s and graduate students of Yale University (USA), on his research...

  17. The Yale Kamusi Project: A Swahili-English, English-Swahili Dictionary.

    Science.gov (United States)

    Hinnebusch, Thomas

    2001-01-01

    Evaluates the strengths and weaknesses of the Yale Online Kamusi project, an electronic Web-based Swahili-English and English-Swahili dictionary. The dictionary is described and checked for comprehensiveness, the adequacy and quality of the glosses and definitions are tested, and a number of recommendations are made to help make it a better and…

  18. Validation of the West Haven-Yale Multidimensional Pain Inventory (WHYMPI for Iranian Patients with Chronic Pain

    Directory of Open Access Journals (Sweden)

    S. M. Mirzamani

    2007-09-01

    Full Text Available Background and Objectives: This study aimed to validate the West Haven-Yale Multidimensional Pain Inventory (WHYMPI for Iranian patients with chronic pain. Methods: 585 patients with chronic pain in legs, back, hands, neck and shoulders were entered into this study. The West Haven-Yale Multidimensional Pain Inventory (WHYMPI was used for assessment of pain in these patients. For validation of this inventory the results were compared with those obtained from Brief Pain Inventory (BPI, Beck Depression Inventory (BDI, State Trait Anxiety Questionnaire and Enrich marriage inventory. Results: Using Cronbach's alpha, validity of the first section of WHYMPI was 0.86, the second section was 0.78, and the third section was 0.75. The Test-retest correlation was 0.95. Also, the correlation of each individual section with the whole inventory was positive and significant.Conclusion: The results indicate that modified form of the West Haven-Yale Multidimensional Pain Inventory (WHYMPI can be used in Iran. Keywords: Inventory; Validity; Pain; Pain Measurement

  19. Environmental science and pleasing architecture. Yale university's most energy-efficient building; Umweltwissenschaft mit Eleganz. Die Universitaet von Yale hat ihr bisher energieeffizientestes Gebaeude eingeweiht

    Energy Technology Data Exchange (ETDEWEB)

    Hirsch, Matthew; Wagner, Neelke

    2010-01-15

    The department of forestry and environmental science of Yale University has a new administrative building. The building has a 105 kW solar power system which supplies 25 percent of the required power. The system was installed on the roof in the conventional way but with an unusual assembly system that resulted in pleasing architecture. (orig.)

  20. The Roots of Research in (political) Persuasion: Ethos, Pathos, Logos and the Yale Studies of Persuasive Communications

    OpenAIRE

    DEMİRDÖĞEN, Ülkü D.

    2010-01-01

    In ancient Greece, Aristotle claimed in his Rhetoric that the function of rhetoric was not to persuade, but to discover the means of persuasion in each case. It is remarkable how the empirical approach towards persuasion embedded in ‘ethos, pathos, logos’ of Aristotle seems to be revisited by the Yale study group in 1950s, with the aim of discovering the laws of persuasive communications in laboratory settings. The contemporary quest carried out by the Yale research program on persuasion ref...

  1. 33 CFR 100.101 - Harvard-Yale Regatta, Thames River, New London, CT.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Harvard-Yale Regatta, Thames... OF HOMELAND SECURITY REGATTAS AND MARINE PARADES SAFETY OF LIFE ON NAVIGABLE WATERS § 100.101 Harvard... passed their positions. At that time, spectator vessels located south of the Harvard Boathouse may...

  2. Yale and the Atomic Bomb Casualty Commission

    International Nuclear Information System (INIS)

    Bowers, J.Z.

    1983-01-01

    This is a description, based largely on personal discussions, of the contributions of men from the Yale University School of Medicine to the saga of the immediate and long-term studies on the medical effects of the atomic bombs at Hiroshima and Nagasaki. They played key roles in the immediate studies of bomb effects, in the creation of long-term studies of delayed effects, and in elevating the Atomic Bomb Casualty Commission after 1955 to a position of excellence in its studies and relations with the Japanese. The accumulation of the information presented in this paper derives from research for the preparation of the history of the Atomic Bomb Casualty Commission. In 1975, the commission was passed to Japanese leadership as the Radiation Effects Research Foundation

  3. Innovating in health care management education: development of an accelerated MBA and MPH degree program at Yale.

    Science.gov (United States)

    Pettigrew, Melinda M; Forman, Howard P; Pistell, Anne F; Nembhard, Ingrid M

    2015-03-01

    Increasingly, there is recognition of the need for individuals with expertise in both management and public health to help health care organizations deliver high-quality and cost-effective care. The Yale School of Public Health and Yale School of Management began offering an accelerated Master of Business Administration (MBA) and Master of Public Health (MPH) joint degree program in the summer of 2014. This new program enables students to earn MBA and MPH degrees simultaneously from 2 fully accredited schools in 22 months. Students will graduate with the knowledge and skills needed to become innovative leaders of health care organizations. We discuss the rationale for the program, the developmental process, the curriculum, benefits of the program, and potential challenges.

  4. The Yale-Classical Archives Corpus

    Directory of Open Access Journals (Sweden)

    Christopher William White

    2016-07-01

    Full Text Available The Yale-Classical Archives Corpus (YCAC contains harmonic and rhythmic information for a dataset of Western European Classical art music. This corpus is based on data from classicalarchives.com, a repository of thousands of user-generated MIDI representations of pieces from several periods of Western European music history. The YCAC makes available metadata for each MIDI file, as well as a list of pitch simultaneities ("salami slices" in the MIDI file. Metadata include the piece's composer, the composer's country of origin, date of composition, genre (e.g., symphony, piano sonata, nocturne, etc., instrumentation, meter, and key. The processing step groups the file's pitches into vertical slices each time a pitch is added or subtracted from the texture, recording the slice's offset (measured in the number of quarter notes separating the event from the file's beginning, highest pitch, lowest pitch, prime form, scale-degrees in relation to the global key (as determined by experts, and local key information (as determined by a windowed key-profile analysis. The corpus contains 13,769 MIDI files by 571 composers yielding over 14,051,144 vertical slices. This paper outlines several properties of this corpus, along with a representative study using this dataset.

  5. Innovating in Health Care Management Education: Development of an Accelerated MBA and MPH Degree Program at Yale

    Science.gov (United States)

    Forman, Howard P.; Pistell, Anne F.; Nembhard, Ingrid M.

    2015-01-01

    Increasingly, there is recognition of the need for individuals with expertise in both management and public health to help health care organizations deliver high-quality and cost-effective care. The Yale School of Public Health and Yale School of Management began offering an accelerated Master of Business Administration (MBA) and Master of Public Health (MPH) joint degree program in the summer of 2014. This new program enables students to earn MBA and MPH degrees simultaneously from 2 fully accredited schools in 22 months. Students will graduate with the knowledge and skills needed to become innovative leaders of health care organizations. We discuss the rationale for the program, the developmental process, the curriculum, benefits of the program, and potential challenges. PMID:25706023

  6. Do grotesco ao sublime: a violência como elemento condicionante de redenção em Tarântula, de Thierry Jonquet

    Directory of Open Access Journals (Sweden)

    Márcia Mucha

    2016-12-01

    Full Text Available The following work aims to demonstrate how violence is conditioning of redemption in Tarântula (1984, by Thierry Jonquet, a novel that gained notoriety after it’s film adaptation with the title "A pele que habito", released in 2011. What is noticeable is that Vincent characters, then with another name, Ève (a woman and Richard Lafargue join the end of the narrative. Although she has been imprisoned and subjected to a drastic transformation of his body and he, on a whim of revenge, made use of his plastic medical knowledge to promote sex change in Vincent without his permission. Even with all the violence that surrounds them, they surrender to each other. From this main event and others that permeate this novel, it is possible to state that this work moves from grotesque, with the issue of violence, to sublime, with the theme of redemption.

  7. Características biológicas de Nipteria panacea Thierry-Mieg (Lepidoptera, Geometridae, desfolhadora do abacateiro, na região serrana do Espírito Santo, Brasil

    Directory of Open Access Journals (Sweden)

    Dirceu Pratissoli

    2002-01-01

    Full Text Available Biological characteristics of Nipteria panacea Thierry-Mieg (Lepidoptera, Geometridae, an avocado tree defoliator, in highlands areas of Espírito Santo, Brazil. The objective of this research was to evaluate some biological characteristics of the avocado tree defoliator, Nipteria panacea Thiery-Mieg, in laboratory. This species showed the mean development cycle of 58.1 days, embryonic period of eight days and egg viability 56.3%. Pos-embryonic development lasted 36.5 days with viability of 48.2%, pupal period 11.6 days with viability of 76.0%, and mean longevity of females was 19.5 days with a production of 177 eggs per female. Other parameters were also observed and discussed.

  8. Matrix elements of Yale potential and level properties of light nuclei

    Energy Technology Data Exchange (ETDEWEB)

    Kumar, N; Prakash, O [Delhi Univ. (India). Dept. of Physics and Astrophysics

    1976-07-01

    Shell model calculations using bare and renormalized matrix elements of the Yale potential are reported for the normal-parity states of A = 6-9 nuclei. Renormalization of the two-body matrix elements using second-order perturbation theory is not found to improve the agreements with the experimental data. Inclusion of the energy shifts of ground state rotational bands in /sup 8/Be and /sup 9/Be are, however, found to improve the agreements with the excitation energies of nuclear levels. The need for carrying out more calculations of these nuclei with realistic forces is pointed out.

  9. The West Haven-Yale Multidimensional Pain Inventory (WHYMPI).

    Science.gov (United States)

    Kerns, R D; Turk, D C; Rudy, T E

    1985-12-01

    The complexity of chronic pain has represented a major dilemma for clinical researchers interested in the reliable and valid assessment of the problem and the evaluation of treatment approaches. The West Haven-Yale Multidimensional Pain Inventory (WHYMPI) was developed in order to fill a widely recognized void in the assessment of clinical pain. Assets of the inventory are its brevity and clarity, its foundation in contemporary psychological theory, its multidimensional focus, and its strong psychometric properties. Three parts of the inventory, comprised of 12 scales, examine the impact of pain on the patients' lives, the responses of others to the patients' communications of pain, and the extent to which patients participate in common daily activities. The instrument is recommended for use in conjunction with behavioral and psychophysiological assessment strategies in the evaluation of chronic pain patients in clinical settings. The utility of the WHYMPI in empirical investigations of chronic pain is also discussed.

  10. Latent class analysis of the Yale-Brown Obsessive-Compulsive Scale symptoms in obsessive-compulsive disorder.

    Science.gov (United States)

    Delucchi, Kevin L; Katerberg, Hilga; Stewart, S Evelyn; Denys, Damiaan A J P; Lochner, Christine; Stack, Denise E; den Boer, Johan A; van Balkom, Anton J L M; Jenike, Michael A; Stein, Dan J; Cath, Danielle C; Mathews, Carol A

    2011-01-01

    Obsessive-compulsive disorder (OCD) is phenomenologically heterogeneous, and findings of underlying structure classification based on symptom grouping have been ambiguous to date. Variable-centered approaches, primarily factor analysis, have been used to identify homogeneous groups of symptoms; but person-centered latent methods have seen little use. This study was designed to uncover sets of homogeneous groupings within 1611 individuals with OCD based on symptoms. Latent class analysis models using 61 obsessive-compulsive symptoms collected from the Yale-Brown Obsessive-Compulsive Scale were fit. Relationships between latent class membership and treatment response, sex, symptom severity, and comorbid tic disorders were tested for relationship to class membership. Latent class analysis models of best fit yielded 3 classes. Classes differed only in frequency of symptom endorsement. Classes with higher symptom endorsement were associated with earlier age of onset, being male, higher Yale-Brown Obsessive-Compulsive Scale symptom severity scores, and comorbid tic disorders. There were no differences in treatment response between classes. These results provide support for the validity of a single underlying latent OCD construct, in addition to the distinct symptom factors identified previously via factor analyses. Copyright © 2011 Elsevier Inc. All rights reserved.

  11. Exploration of the central dogma at the interface of chemistry and biology: 2010 Yale Chemical Biology Symposium.

    Science.gov (United States)

    Zhou, Alice Qinhua

    2010-09-01

    Ever since the term "central dogma" was coined in 1958, researchers have sought to control information flow from nucleic acids to proteins. Talks delivered by Drs. Anna Pyle and Hiroaki Suga at this year's Chemical Biology Symposium at Yale in May 2010 applauded recent advances in this area, at the interface between chemistry and biology.

  12. Five days of successful oral alimentation for hospitalized patients based upon passing the Yale Swallow Protocol.

    Science.gov (United States)

    Leder, Steven B; Suiter, Debra M

    2014-09-01

    This study aimed to determine the success of oral alimentation and patient retention rate 1 to 5 days after passing the Yale Swallow Protocol. Participants were 200 consecutive acute care inpatients referred for swallow assessment. Inclusion criteria were adequate cognitive abilities to participate safely, completing an oral mechanism examination, and passing the 3-ounce water swallow challenge. Exclusion criteria were altered mental status, failing the 3-ounce challenge, preadmission dysphagia, head-of-bed restrictions alimentation and retention rate. All patients who remained medically and neurologically stable drank thin liquids and ate successfully 1 to 5 days after passing the protocol. Mean (SD) volume of liquid ingested per day was 474.2 (435.5) cc. Patient retention declined steadily from day of testing (n = 200) through post-testing day 5 (n = 95). Passing the Yale Swallow Protocol allowed for initial determination of aspiration risk followed by successful oral alimentation for 1 to 5 days in medically and neurologically stable acute care hospitalized patients and without the need for instrumental dysphagia testing. The decline in patient retention was expected because of increasingly rapid transit through the acute care setting, which often renders longer follow-up problematic. © The Author(s) 2014.

  13. Sensitivity of the Modified Children's Yale-Brown Obsessive Compulsive Scale to Detect Change: Results from Two Multi-Site Trials

    Science.gov (United States)

    Scahill, Lawrence; Sukhodolsky, Denis G.; Anderberg, Emily; Dimitropoulos, Anastasia; Dziura, James; Aman, Michael G.; McCracken, James; Tierney, Elaine; Hallett, Victoria; Katz, Karol; Vitiello, Benedetto; McDougle, Christopher

    2016-01-01

    Repetitive behavior is a core feature of autism spectrum disorder. We used 8-week data from two federally funded, multi-site, randomized trials with risperidone conducted by the Research Units on Pediatric Psychopharmacology Autism Network to evaluate the sensitivity of the Children's Yale-Brown Obsessive Compulsive Scale modified for autism…

  14. Yale High Energy Physics Research: Precision Studies of Reactor Antineutrinos

    International Nuclear Information System (INIS)

    Heeger, Karsten M.

    2014-01-01

    This report presents experimental research at the intensity frontier of particle physics with particular focus on the study of reactor antineutrinos and the precision measurement of neutrino oscillations. The experimental neutrino physics group of Professor Heeger and Senior Scientist Band at Yale University has had leading responsibilities in the construction and operation of the Daya Bay Reactor Antineutrino Experiment and made critical contributions to the discovery of non-zero$\\theta . Heeger and Band led the Daya Bay detector management team and are now overseeing the operations of the antineutrino detectors. Postdoctoral researchers and students in this group have made leading contributions to the Daya Bay analysis including the prediction of the reactor antineutrino flux and spectrum, the analysis of the oscillation signal, and the precision determination of the target mass yielding unprecedented precision in the relative detector uncertainty. Heeger's group is now leading an R\\&D effort towards a short-baseline oscillation experiment, called PROSPECT, at a US research reactor and the development of antineutrino detectors with advanced background discrimination.

  15. Yale High Energy Physics Research: Precision Studies of Reactor Antineutrinos

    Energy Technology Data Exchange (ETDEWEB)

    Heeger, Karsten M. [Yale Univ., New Haven, CT (United States)

    2014-09-13

    This report presents experimental research at the intensity frontier of particle physics with particular focus on the study of reactor antineutrinos and the precision measurement of neutrino oscillations. The experimental neutrino physics group of Professor Heeger and Senior Scientist Band at Yale University has had leading responsibilities in the construction and operation of the Daya Bay Reactor Antineutrino Experiment and made critical contributions to the discovery of non-zero$\\theta_{13}$. Heeger and Band led the Daya Bay detector management team and are now overseeing the operations of the antineutrino detectors. Postdoctoral researchers and students in this group have made leading contributions to the Daya Bay analysis including the prediction of the reactor antineutrino flux and spectrum, the analysis of the oscillation signal, and the precision determination of the target mass yielding unprecedented precision in the relative detector uncertainty. Heeger's group is now leading an R\\&D effort towards a short-baseline oscillation experiment, called PROSPECT, at a US research reactor and the development of antineutrino detectors with advanced background discrimination.

  16. Health physics aspects of the Yale Heavy Ion Linear Accelerator dismantling project

    International Nuclear Information System (INIS)

    Price, K.W.; Holeman, G.R.

    1976-01-01

    A program for the disassembly of the Yale Heavy Ion Linear Accelerator was initiated January 1, 1975. The object of the disassembly was to render the accelerator complex free of radioactive contamination in order that the area may be used for other University purposes. In addition, any salvage of metal parts was a desirable goal of the dismantling procedure. A systematic removal of all contaminated material began immediately. Portable survey instruments, swipe surveys, and sodium iodide gamma ray spectra were used as indicators of contamination. Apparatus in the direct beam line seemed to pose the most significant hazard to personnel. As beam components were eliminated, radioactive contamination was significantly reduced. Certain accelerator parts had to be machined in order to salvage non-contaminated metal, and the health physics aspects of this procedure are described. Isotopes found in the surveys included 22 Na, 54 Mn, 60 Co, 65 Zn and 75 Se, which were predominately beam activation products of accelerator components. Final surveys indicated the area free of radioactive contamination

  17. Dissecting the Yale-Brown Obsessive-Compulsive Scale severity scale to understand the routes for symptomatic improvement in obsessive-compulsive disorder.

    Science.gov (United States)

    Costa, Daniel L da Conceição; Barbosa, Veronica S; Requena, Guaraci; Shavitt, Roseli G; Pereira, Carlos A de Bragança; Diniz, Juliana B

    2017-10-01

    We aimed to investigate which items of the Yale-Brown Obsessive-Compulsive Severity Scale best discriminate the reduction in total scores in obsessive-compulsive disorder patients after 4 and 12 weeks of pharmacological treatment. Data from 112 obsessive-compulsive disorder patients who received fluoxetine (⩽80 mg/day) for 12 weeks were included. Improvement indices were built for each Yale-Brown Obsessive-Compulsive Severity Scale item at two timeframes: from baseline to week 4 and from baseline to week 12. Indices for each item were correlated with the total scores for obsessions and compulsions and then ranked by correlation coefficient. A correlation coefficient ⩾0.7 was used to identify items that contributed significantly to reducing obsessive-compulsive disorder severity. At week 4, the distress items reached the threshold of 0.7 for improvement on the obsession and compulsion subscales although, contrary to our expectations, there was greater improvement in the control items than in the distress items. At week 12, there was greater improvement in the time, interference, and control items than in the distress items. The use of fluoxetine led first to reductions in distress and increases in control over symptoms before affecting the time spent on, and interference from, obsessions and compulsions. Resistance did not correlate with overall improvement. Understanding the pathway of improvement with pharmacological treatment in obsessive-compulsive disorder may provide clues about how to optimize the effects of medication.

  18. Correlation of burnout syndrome with specific coping strategies, behaviors, and spiritual attitudes among interns at Yale University, New Haven, USA

    Directory of Open Access Journals (Sweden)

    Benjamin R. Doolittle

    2015-08-01

    Full Text Available Purpose: This study aimed to determine the correlation of burnout syndrome with specific coping strategies, behaviors, and spiritual attitudes among interns in internal medicine, primary care, and internal medicine/pediatrics residency programs at two institutions. Methods: Intern physicians completed anonymous voluntary surveys prior to starting the internship in June 2009 and in the middle of the internship in February 2010. Three validated survey instruments were used to explore burnout, coping, and spiritual attitudes: the Maslach Burnout Inventory, the COPE Inventory, and the Hatch Spiritual Involvement and Beliefs Scale. The interns were in programs at the Yale University School of Medicine and a Yale-affiliated community hospital, New Haven, Connecticut, USA. Results: The prevalence of self-identified burnout prior to starting the internship was 1/66 (1.5% in June 2009, increasing to 10/53 (18.9% in February 2010 (P<0.0001. From June 2009 to February 2010, the prevalence of high emotional exhaustion increased from 30/66 (45.5% to 45/53 (84.9% (P<0.0001, and that of high depersonalization increased from 42/66 (63.6% to 45/53 (84.9% (P=0.01. Interns who employed the strategies of acceptance and active coping were less likely to experience emotional exhaustion and depersonalization (P<0.05. Perceptions of high personal accomplishment was 75.5% and was positively correlated with total scores on the Hatch Spiritual Involvement and Beliefs Scale, as well as the internal/fluid and existential/meditative domains of that instrument. Specific behaviors did not impact burnout. Conclusion: Burnout increased during the intern year. Acceptance, active coping, and spirituality were correlated with less burnout. Specific behaviors were not correlated with burnout domains.

  19. Correlation of burnout syndrome with specific coping strategies, behaviors, and spiritual attitudes among interns at Yale University, New Haven, USA.

    Science.gov (United States)

    Doolittle, Benjamin R; Windish, Donna M

    2015-01-01

    This study aimed to determine the correlation of burnout syndrome with specific coping strategies, behaviors, and spiritual attitudes among interns in internal medicine, primary care, and internal medicine/pediatrics residency programs at two institutions. Intern physicians completed anonymous voluntary surveys prior to starting the internship in June 2009 and in the middle of the internship in February 2010. Three validated survey instruments were used to explore burnout, coping, and spiritual attitudes: the Maslach Burnout Inventory, the COPE Inventory, and the Hatch Spiritual Involvement and Beliefs Scale. The interns were in programs at the Yale University School of Medicine and a Yale-affiliated community hospital, New Haven, Connecticut, USA. The prevalence of self-identified burnout prior to starting the internship was 1/66 (1.5%) in June 2009, increasing to 10/53 (18.9%) in February 2010 (P<0.0001). From June 2009 to February 2010, the prevalence of high emotional exhaustion increased from 30/66 (45.5%) to 45/53 (84.9%) (P<0.0001), and that of high depersonalization increased from 42/66 (63.6%) to 45/53 (84.9%) (P=0.01). Interns who employed the strategies of acceptance and active coping were less likely to experience emotional exhaustion and depersonalization (P<0.05). Perceptions of high personal accomplishment was 75.5% and was positively correlated with total scores on the Hatch Spiritual Involvement and Beliefs Scale, as well as the internal/fluid and existential/meditative domains of that instrument. Specific behaviors did not impact burnout. Burnout increased during the intern year. Acceptance, active coping, and spirituality were correlated with less burnout. Specific behaviors were not correlated with burnout domains.

  20. Promoting convergence: The integrated graduate program in physical and engineering biology at Yale University, a new model for graduate education.

    Science.gov (United States)

    Noble, Dorottya B; Mochrie, Simon G J; O'Hern, Corey S; Pollard, Thomas D; Regan, Lynne

    2016-11-12

    In 2008, we established the Integrated Graduate Program in Physical and Engineering Biology (IGPPEB) at Yale University. Our goal was to create a comprehensive graduate program to train a new generation of scientists who possess a sophisticated understanding of biology and who are capable of applying physical and quantitative methodologies to solve biological problems. Here we describe the framework of the training program, report on its effectiveness, and also share the insights we gained during its development and implementation. The program features co-teaching by faculty with complementary specializations, student peer learning, and novel hands-on courses that facilitate the seamless blending of interdisciplinary research and teaching. It also incorporates enrichment activities to improve communication skills, engage students in science outreach, and foster a cohesive program cohort, all of which promote the development of transferable skills applicable in a variety of careers. The curriculum of the graduate program is integrated with the curricular requirements of several Ph.D.-granting home programs in the physical, engineering, and biological sciences. Moreover, the wide-ranging recruiting activities of the IGPPEB serve to enhance the quality and diversity of students entering graduate school at Yale. We also discuss some of the challenges we encountered in establishing and optimizing the program, and describe the institution-level changes that were catalyzed by the introduction of the new graduate program. The goal of this article is to serve as both an inspiration and as a practical "how to" manual for those who seek to establish similar programs at their own institutions. © 2016 by The International Union of Biochemistry and Molecular Biology, 44(6):537-549, 2016. © 2016 The Authors Biochemistry and Molecular Biology Education published by Wiley Periodicals, Inc. on behalf of International Union of Biochemistry and Molecular Biology.

  1. Book Review: Market Liquidity: Theory, Evidence, and Policy

    DEFF Research Database (Denmark)

    Boscan, Luis

    2014-01-01

    Review of: Market Liquidity: Theory, Evidence, and Policy / by Thierry Foucault, Marco Pagano and Ailsa Röell. Oxford University Press. April 2013.......Review of: Market Liquidity: Theory, Evidence, and Policy / by Thierry Foucault, Marco Pagano and Ailsa Röell. Oxford University Press. April 2013....

  2. A multicenter examination and strategic revisions of the Yale Global Tic Severity Scale.

    Science.gov (United States)

    McGuire, Joseph F; Piacentini, John; Storch, Eric A; Murphy, Tanya K; Ricketts, Emily J; Woods, Douglas W; Walkup, John W; Peterson, Alan L; Wilhelm, Sabine; Lewin, Adam B; McCracken, James T; Leckman, James F; Scahill, Lawrence

    2018-05-08

    To examine the internal consistency and distribution of the Yale Global Tic Severity Scale (YGTSS) scores to inform modification of the measure. This cross-sectional study included 617 participants with a tic disorder (516 children and 101 adults), who completed an age-appropriate diagnostic interview and the YGTSS to evaluate tic symptom severity. The distributions of scores on YGTSS dimensions were evaluated for normality and skewness. For dimensions that were skewed across motor and phonic tics, a modified Delphi consensus process was used to revise selected anchor points. Children and adults had similar clinical characteristics, including tic symptom severity. All participants were examined together. Strong internal consistency was identified for the YGTSS Motor Tic score (α = 0.80), YGTSS Phonic Tic score (α = 0.87), and YGTSS Total Tic score (α = 0.82). The YGTSS Total Tic and Impairment scores exhibited relatively normal distributions. Several subscales and individual item scales departed from a normal distribution. Higher scores were more often used on the Motor Tic Number, Frequency, and Intensity dimensions and the Phonic Tic Frequency dimension. By contrast, lower scores were more often used on Motor Tic Complexity and Interference, and Phonic Tic Number, Intensity, Complexity, and Interference. The YGTSS exhibits good internal consistency across children and adults. The parallel findings across Motor and Phonic Frequency, Complexity, and Interference dimensions prompted minor revisions to the anchor point description to promote use of the full range of scores in each dimension. Specific minor revisions to the YGTSS Phonic Tic Symptom Checklist were also proposed. © 2018 American Academy of Neurology.

  3. The Prevalence of Food Addiction as Assessed by the Yale Food Addiction Scale: A Systematic Review

    Directory of Open Access Journals (Sweden)

    Kirrilly M. Pursey

    2014-10-01

    Full Text Available Obesity is a global issue and it has been suggested that an addiction to certain foods could be a factor contributing to overeating and subsequent obesity. Only one tool, the Yale Food Addiction Scale (YFAS has been developed to specifically assess food addiction. This review aimed to determine the prevalence of food addiction diagnosis and symptom scores, as assessed by the YFAS. Published studies to July 2014 were included if they reported the YFAS diagnosis or symptom score and were published in the English language. Twenty-five studies were identified including a total of 196,211 predominantly female, overweight/obese participants (60%. Using meta-analysis, the weighted mean prevalence of YFAS food addiction diagnosis was 19.9%. Food addiction (FA diagnosis was found to be higher in adults aged >35 years, females, and overweight/obese participants. Additionally, YFAS diagnosis and symptom score was higher in clinical samples compared to non-clinical counterparts. YFAS outcomes were related to a range of other eating behavior measures and anthropometrics. Further research is required to explore YFAS outcomes across a broader spectrum of ages, other types of eating disorders and in conjunction with weight loss interventions to confirm the efficacy of the tool to assess for the presence of FA.

  4. A PUBLIC, K-SELECTED, OPTICAL-TO-NEAR-INFRARED CATALOG OF THE EXTENDED CHANDRA DEEP FIELD SOUTH (ECDFS) FROM THE MULTIWAVELENGTH SURVEY BY YALE-CHILE (MUSYC)

    International Nuclear Information System (INIS)

    Taylor, Edward N.; Franx, Marijn; Quadri, Ryan F.; Damen, Maaike; Hildebrandt, Hendrik; Van Dokkum, Pieter G.; Herrera, David; Gawiser, Eric; Bell, Eric F.; Barrientos, L. Felipe; Blanc, Guillermo A.; Castander, Francisco J.; Gonzalez-Perez, Violeta; Hall, Patrick B.; Kriek, Mariska; Labbe, Ivo; Lira, Paulina; Maza, Jose; Rudnick, Gregory; Treister, Ezequiel

    2009-01-01

    We present a new, K-selected, optical-to-near infrared photometric catalog of the Extended Chandra Deep Field South (ECDFS), making it publicly available to the astronomical community. 22 Imaging and spectroscopy data and catalogs are freely available through the MUSYC Public Data Release webpage: http://www.astro.yale.edu/MUSYC/. The data set is founded on publicly available imaging, supplemented by original z'JK imaging data collected as part of the MUltiwavelength Survey by Yale-Chile (MUSYC). The final photometric catalog consists of photometry derived from UU 38 BVRIz'JK imaging covering the full 1/2 x 1/2 square circ of the ECDFS, plus H-band photometry for approximately 80% of the field. The 5σ flux limit for point sources is K (AB) tot = 22.0. This is also the nominal completeness and reliability limit of the catalog: the empirical completeness for 21.75 85%. We have verified the quality of the catalog through both internal consistency checks, and comparisons to other existing and publicly available catalogs. As well as the photometric catalog, we also present catalogs of photometric redshifts and rest-frame photometry derived from the 10-band photometry. We have collected robust spectroscopic redshift determinations from published sources for 1966 galaxies in the catalog. Based on these sources, we have achieved a (1σ) photometric redshift accuracy of Δz/(1 + z) = 0.036, with an outlier fraction of 7.8%. Most of these outliers are X-ray sources. Finally, we describe and release a utility for interpolating rest-frame photometry from observed spectral energy distributions, dubbed InterRest. 23 InterRest is available via http://www.strw.leidenuniv.nl/~ent/InterRest. Documentation and a complete walkthrough can be found at the same address.

  5. Why They Fly: An Expectancy-Based Analysis of the Factors that Motivate Commissioned Army Aviators to Gain Flying Experience

    Science.gov (United States)

    2007-06-15

    applicable to understanding future behaviors" (Boyce et. al, 2005). Expectancy theory ( Vroom , 1964) proposes that workers will work in ways geared...instrumentality ( Vroom , 1964). Recently, Van Eerde and Thierry (1996) found that the multiplicative models did not yield more information than simply analyzing...Thierry, H. (1996). Vroom’s expectancy models and work-related criteria: A meta-analysis. Journal of Applied Psychology, 81, 575-586. Vice Chief of

  6. Measurement invariance of the Yale Food Addiction Scale 2.0 across gender and racial groups.

    Science.gov (United States)

    Carr, Meagan M; Catak, Pelin D; Pejsa-Reitz, Megan C; Saules, Karen K; Gearhardt, Ashley N

    2017-08-01

    Food addiction describes a psychological and behavioral eating pattern that is similar to the experience of those compulsively taking drugs of abuse. Recent developments related to food addiction, including the development and validation of an updated measure (Yale Food Addiction Scale 2.0; Gearhardt, Corbin, & Brownell, 2016), have increased knowledge as to the prevalence and associated correlates of food addiction. However, less is known about the phenomenological experience of food addiction in diverse samples or how the existing measure of food addiction performs in heterogeneous samples. In a cross-sectional survey design, using a diverse sample of undergraduate students (N = 642) tests of measurement invariance were performed. Confirmatory factor analysis supported the hypothesized factor structure, indicating a single latent construct of food addiction modeled by 11 dichotomous indicators, in samples of White and Black participants as well as samples of men and women. Measurement invariance testing across the various demographic groups broadly provided good psychometric support for use of the measure. However, a single indicator related to attempts to cut down on highly palatable food varied across men and women. Thus, when using the measure in mixed gender samples researchers may consider obtaining additional information regarding gender and its relative impact on the experience of food addiction, particularly with respect to efforts to quit or cut down intake of highly palatable foods. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  7. Validity and reliability of the Brazilian version of Yale-Brown obsessive compulsive scale-shopping version (YBOCS-SV).

    Science.gov (United States)

    Leite, Priscilla Lourenço; Filomensky, Tatiana Zambrano; Black, Donald W; Silva, Adriana Cardoso

    2014-08-01

    The Yale-Brown Obsessive Compulsive Scale-Shopping Version (YBOCS-SV) is considered the gold standard in the assessment of shopping severity. It is designed to assess cognitions and behaviors relating to compulsive buying behavior. The present study aims to assess the validity of the Brazilian version of this scale. For the study, composed the sample 610 participants: 588 subjects of a general population and 22 compulsive buyers. Factorial analysis was performed to assess the relations and the correlation between the YBOCS-SV, the Compulsive Buying Scale (CBS), and Richmond Compulsive Buying Scale (RCBS), was assessed using Pearson coefficient, for study of convergent and divergent validity. Cronbach's alpha coefficients were used to assess internal consistency. The results show good to excellent psychometric parameters for the YBOCS-SV in its Brazilian version. With regard to correlations, the YBOCS-SV is inversely and proportionally correlated with CBS and the RCBS, indicating that the YBOCS-SV is an excellent instrument for screening compulsive buying. The YBOCS-SV presented high alpha coefficient of Cronbach's alpha (0.92), demonstrating good reliability. The Brazilian version of the YBOCS-SV is indicated to diagnose compulsive buying disorder, and likely use for the purposes intended in the Brazilian population. Copyright © 2014 Elsevier Inc. All rights reserved.

  8. Estudo transversal de ansiedade pré-operatória em crianças: utilização da escala de Yale modificada Estudio transversal de ansiedad preoperatoria en niños: utilización de la escala de Yale modificada A transversal study on preoperative anxiety in children: use of the modified Yale scale

    Directory of Open Access Journals (Sweden)

    Álvaro Antônio Guaratini

    2006-12-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: O emprego de escalas pode ser útil no reconhecimento dos estados de ansiedade, direcionando medidas que previnam complicações decorrentes de níveis elevados de ansiedade. A escala de ansiedade pré-operatória de Yale modificada (EAPY-m foi desenvolvida para avaliação da ansiedade em crianças na idade pré-escolar no momento da indução da anestesia. Essa escala possui caráter observacional e é rápida de ser completada. Os estudos sobre ansiedade em crianças no período pré-operatório não fazem menção à ansiedade no momento da avaliação pré-anestésica ambulatorial (APA. Este estudo transversal procurou avaliar o nível e a prevalência de ansiedade no momento da APA e da consulta clínica utilizando a escala EAPY-m, em crianças em idade pré-escolar. MÉTODO: Foram selecionadas 100 crianças, estado físico ASA I e IIi: G PED = 50 crianças a serem submetidas à avaliação clínica; G APA = 50 crianças a serem submetidas à apa para programação cirúrgica. O estudo se desenvolveu na sala de espera dos ambulatórios de pediatria e de apa enquanto as crianças aguardavam as consultas. Dois observadores aplicaram a escala EAPY-m de forma independente. Os parâmetros analisados foram dados sociodemográficos; mediana e porcentagem de pacientes com ansiedade (EAPY-m > 30. Foi realizada a análise estatística, sendo considerado significativo p JUSTIFICATIVA Y OBJETIVOS: La utilización de escalas puede ser útil en el reconocimiento de los estados de ansiedad, dirigido a medidas que prevengan complicaciones provenientes de niveles elevados de ansiedad. La Escala de Ansiedad Preoperatoria de Yale modificada (EAPY-m fue desarrollada para la evaluación de la ansiedad en niños en la edad preescolar al momento de la inducción de la anestesia. Esa escala posee un carácter de observación y es muy fácil para ser completada. Los estudios sobre ansiedad en niños en el período preoperatorio no

  9. Staff members with 25 years' service at CERN in 2010

    CERN Multimedia

    HR Department

    2010-01-01

    The 38 staff members who are celebrating 25 years at CERN in 2010 were invited by the Director-General to a reception in their honour on 21 October. ASBURY David IT HEGARTY Seamus HR BAUDRENGHIEN Philippe BE ISNARD Christian IT BERGSMA Felix PH JONES Robert IT BERNAL Jean-Manuel TE JOUBERJEAN Franck IT BERRIG Olav Ejner BE LAGRANGE Thierry FP BONT Hillebrand GS MARIN Antonio BE BOURGEOIS Nicolas PH MESENGE Pascal EN BOURREL Thierry EN MISSIAEN Dominique   BE ...

  10. Food Addiction and Bulimia Nervosa: New Data Based on the Yale Food Addiction Scale 2.0.

    Science.gov (United States)

    de Vries, Sarah-Kristin; Meule, Adrian

    2016-11-01

    Previous research on 'food addiction' as measured with the Yale Food Addiction Scale (YFAS) showed a large overlap between addiction-like eating and bulimia nervosa. Most recently, a revised version of the YFAS has been developed according to the changes made in the diagnostic criteria for substance use disorder in the Diagnostic and Statistical Manual of Mental Disorders fifth edition. The current study examined prevalence and correlates of the YFAS2.0 in individuals with bulimia (n = 115) and controls (n = 341). Ninety-six per cent of participants with bulimia and 14% of controls received a YFAS2.0 diagnosis. A higher number of YFAS2.0 symptoms was associated with lower interoceptive awareness, higher depressiveness, and higher impulsivity in both groups. However, a higher number of YFAS2.0 symptoms was associated with higher body mass and weight suppression in controls only and not in participants with bulimia. The current study is the first to show a large overlap between bulimia and 'food addiction' as measured with the YFAS2.0, replicating and extending findings from studies, which used the previous version of the YFAS. Compensatory weight control behaviours in individuals with bulimia likely alleviate the association between addiction-like eating and higher body mass. Thus, the large overlap between bulimia and 'food addiction' should be taken into consideration when examining the role of addiction-like eating in weight gain and obesity. Copyright © 2016 John Wiley & Sons, Ltd and Eating Disorders Association. Copyright © 2016 John Wiley & Sons, Ltd and Eating Disorders Association.

  11. Evaluation of the Yale New Haven Readmission Risk Score for Pneumonia in a General Hospital Population.

    Science.gov (United States)

    Schaefer, Gabrielle; El-Kareh, Robert; Quartarolo, Jennifer; Seymann, Gregory

    2017-09-01

    The Yale New Haven Readmission Risk Score (YNHRRS) for pneumonia is a clinical prediction tool developed to assess risk for 30-day readmission. This tool was validated in a cohort of Medicare patients; generalizability to a broader patient population has not been evaluated. In addition, it lacks indicators of functional status or social support, which have been shown in other studies to be predictors of readmission. The objective of this study was to evaluate the generalizability of the YNHRRS for pneumonia in a general population of hospitalized patients, and assess the impact of incorporating measures of functional status and social support on its predictive value. This retrospective chart review comprised all patients admitted to a 563-bed academic medical center with a primary diagnosis of pneumonia between March 2014 and March 2015. Abstraction of clinical variables allowed calculation of the YNHRRS and additional indicators of functional status and social support. The primary outcome was 30-day readmission rate. We created a logistic regression model to predict readmission using the YNHRRS, functional status, and social support as covariates. Among 270 discharges with pneumonia, the observed readmission rate was 23%. The YNHRRS was a significant predictor of readmission in our multivariate model, with an odds ratio of 2.20 (95% confidence interval, 1.29-3.73) for each 10% increase in calculated risk. Indicators of functional status and social support were not significant predictors of readmission. The YNHRRS can be applied to an unselected population as a tool to predict patients with pneumonia at risk for readmission. Copyright © 2017 Elsevier Inc. All rights reserved.

  12. The Development and Validation of the Bergen–Yale Sex Addiction Scale With a Large National Sample

    Directory of Open Access Journals (Sweden)

    Cecilie S. Andreassen

    2018-03-01

    Full Text Available The view that problematic excessive sexual behavior (“sex addiction” is a form of behavioral addiction has gained more credence in recent years, but there is still considerable controversy regarding operationalization of the concept. Furthermore, most previous studies have relied on small clinical samples. The present study presents a new method for assessing sex addiction—the Bergen–Yale Sex Addiction Scale (BYSAS—based on established addiction components (i.e., salience/craving, mood modification, tolerance, withdrawal, conflict/problems, and relapse/loss of control. Using a cross-sectional survey, the BYSAS was administered to a broad national sample of 23,533 Norwegian adults [aged 16–88 years; mean (± SD age = 35.8 ± 13.3 years], together with validated measures of the Big Five personality traits, narcissism, self-esteem, and a measure of sexual addictive behavior. Both an exploratory and a confirmatory factor analysis (RMSEA = 0.046, CFI = 0.998, TLI = 0.996 supported a one-factor solution, although a local dependence between two items (Items 1 and 2 was detected. Furthermore, the scale had good internal consistency (Cronbach's α = 0.83. The BYSAS correlated significantly with the reference scale (r = 0.52, and demonstrated similar patterns of convergent and discriminant validity. The BYSAS was positively related to extroversion, neuroticism, intellect/imagination, and narcissism, and negatively related to conscientiousness, agreeableness, and self-esteem. High scores on the BYSAS were more prevalent among those who were men, single, of younger age, and with higher education. The BYSAS is a brief, and psychometrically reliable and valid measure for assessing sex addiction. However, further validation of the BYSAS is needed in other countries and contexts.

  13. The Development and Validation of the Bergen–Yale Sex Addiction Scale With a Large National Sample

    Science.gov (United States)

    Andreassen, Cecilie S.; Pallesen, Ståle; Griffiths, Mark D.; Torsheim, Torbjørn; Sinha, Rajita

    2018-01-01

    The view that problematic excessive sexual behavior (“sex addiction”) is a form of behavioral addiction has gained more credence in recent years, but there is still considerable controversy regarding operationalization of the concept. Furthermore, most previous studies have relied on small clinical samples. The present study presents a new method for assessing sex addiction—the Bergen–Yale Sex Addiction Scale (BYSAS)—based on established addiction components (i.e., salience/craving, mood modification, tolerance, withdrawal, conflict/problems, and relapse/loss of control). Using a cross-sectional survey, the BYSAS was administered to a broad national sample of 23,533 Norwegian adults [aged 16–88 years; mean (± SD) age = 35.8 ± 13.3 years], together with validated measures of the Big Five personality traits, narcissism, self-esteem, and a measure of sexual addictive behavior. Both an exploratory and a confirmatory factor analysis (RMSEA = 0.046, CFI = 0.998, TLI = 0.996) supported a one-factor solution, although a local dependence between two items (Items 1 and 2) was detected. Furthermore, the scale had good internal consistency (Cronbach's α = 0.83). The BYSAS correlated significantly with the reference scale (r = 0.52), and demonstrated similar patterns of convergent and discriminant validity. The BYSAS was positively related to extroversion, neuroticism, intellect/imagination, and narcissism, and negatively related to conscientiousness, agreeableness, and self-esteem. High scores on the BYSAS were more prevalent among those who were men, single, of younger age, and with higher education. The BYSAS is a brief, and psychometrically reliable and valid measure for assessing sex addiction. However, further validation of the BYSAS is needed in other countries and contexts. PMID:29568277

  14. The Development and Validation of the Bergen-Yale Sex Addiction Scale With a Large National Sample.

    Science.gov (United States)

    Andreassen, Cecilie S; Pallesen, Ståle; Griffiths, Mark D; Torsheim, Torbjørn; Sinha, Rajita

    2018-01-01

    The view that problematic excessive sexual behavior ("sex addiction") is a form of behavioral addiction has gained more credence in recent years, but there is still considerable controversy regarding operationalization of the concept. Furthermore, most previous studies have relied on small clinical samples. The present study presents a new method for assessing sex addiction-the Bergen-Yale Sex Addiction Scale (BYSAS)-based on established addiction components (i.e., salience/craving, mood modification, tolerance, withdrawal, conflict/problems, and relapse/loss of control). Using a cross-sectional survey, the BYSAS was administered to a broad national sample of 23,533 Norwegian adults [aged 16-88 years; mean (± SD ) age = 35.8 ± 13.3 years], together with validated measures of the Big Five personality traits, narcissism, self-esteem, and a measure of sexual addictive behavior. Both an exploratory and a confirmatory factor analysis (RMSEA = 0.046, CFI = 0.998, TLI = 0.996) supported a one-factor solution, although a local dependence between two items (Items 1 and 2) was detected. Furthermore, the scale had good internal consistency (Cronbach's α = 0.83). The BYSAS correlated significantly with the reference scale ( r = 0.52), and demonstrated similar patterns of convergent and discriminant validity. The BYSAS was positively related to extroversion, neuroticism, intellect/imagination, and narcissism, and negatively related to conscientiousness, agreeableness, and self-esteem. High scores on the BYSAS were more prevalent among those who were men, single, of younger age, and with higher education. The BYSAS is a brief, and psychometrically reliable and valid measure for assessing sex addiction. However, further validation of the BYSAS is needed in other countries and contexts.

  15. Validation of the French Version of the DSM-5 Yale Food Addiction Scale in a Nonclinical Sample.

    Science.gov (United States)

    Brunault, Paul; Courtois, Robert; Gearhardt, Ashley N; Gaillard, Philippe; Journiac, Kevin; Cathelain, Sarah; Réveillère, Christian; Ballon, Nicolas

    2017-03-01

    The Yale Food Addiction Scale (YFAS) is the only questionnaire that assesses food addiction (FA) based on substance dependence criteria in the Diagnostic and Statistical Manual of Mental Disorders (DSM), Fourth Edition, Text Revision. Following recent updating of addiction criteria, a new DSM-5 version (YFAS 2.0) has been developed. Our study tested the psychometric properties of the French YFAS 2.0 in a nonclinical population. We assessed 330 nonclinical participants for FA (French YFAS 2.0), eating behaviour, and eating disorder (Binge Eating Scale, Emotional Overeating Questionnaire, Three-Factor Eating Questionnaire-R18, Questionnaire on Eating and Weight Patterns-Revised, Eating Disorder Diagnostic Scale). We tested the scale's factor structure (confirmatory factor analysis based on 11 diagnostic criteria), internal consistency, and construct and incremental validity. Prevalence of FA was 8.2%. Our results supported a 1-factor structure similar to the US version. In both its diagnostic and symptom count versions, the YFAS 2.0 had good internal consistency (Kuder-Richardson alpha was 0.83) and was associated with body mass index (BMI), binge eating, uncontrolled and emotional eating, binge eating disorder, and cognitive restraint. FA predicted BMI above and beyond binge eating frequency. Females had a higher prevalence of FA than males but not more FA symptoms. We validated a psychometrically sound French version of the YFAS 2.0 in a nonclinical population, in both its symptom count and diagnostic versions. Future studies should investigate psychometric properties of this questionnaire in clinical populations potentially at risk for FA (that is, patients with obesity, diabetes, hypertension, or other metabolic syndrome risk factors).

  16. THE MULTIWAVELENGTH SURVEY BY YALE-CHILE (MUSYC): DEEP MEDIUM-BAND OPTICAL IMAGING AND HIGH-QUALITY 32-BAND PHOTOMETRIC REDSHIFTS IN THE ECDF-S

    International Nuclear Information System (INIS)

    Cardamone, Carolin N.; Van Dokkum, Pieter G.; Urry, C. Megan; Brammer, Gabriel; Taniguchi, Yoshi; Gawiser, Eric; Bond, Nicholas; Taylor, Edward; Damen, Maaike; Treister, Ezequiel; Cobb, Bethany E.; Schawinski, Kevin; Lira, Paulina; Murayama, Takashi; Saito, Tomoki; Sumikawa, Kentaro

    2010-01-01

    We present deep optical 18-medium-band photometry from the Subaru telescope over the ∼30' x 30' Extended Chandra Deep Field-South, as part of the Multiwavelength Survey by Yale-Chile (MUSYC). This field has a wealth of ground- and space-based ancillary data, and contains the GOODS-South field and the Hubble Ultra Deep Field. We combine the Subaru imaging with existing UBVRIzJHK and Spitzer IRAC images to create a uniform catalog. Detecting sources in the MUSYC 'BVR' image we find ∼40,000 galaxies with R AB 3.5. For 0.1 < z < 1.2, we find a 1σ scatter in Δz/(1 + z) of 0.007, similar to results obtained with a similar filter set in the COSMOS field. As a demonstration of the data quality, we show that the red sequence and blue cloud can be cleanly identified in rest-frame color-magnitude diagrams at 0.1 < z < 1.2. We find that ∼20% of the red sequence galaxies show evidence of dust emission at longer rest-frame wavelengths. The reduced images, photometric catalog, and photometric redshifts are provided through the public MUSYC Web site.

  17. Validation of the Italian version of the Yale Food Addiction Scale 2.0 (I-YFAS 2.0) in a sample of undergraduate students.

    Science.gov (United States)

    Aloi, Matteo; Rania, Marianna; Rodríguez Muñoz, Rita Cristina; Jiménez Murcia, Susana; Fernández-Aranda, Fernando; De Fazio, Pasquale; Segura-Garcia, Cristina

    2017-09-01

    Food addiction (FA) refers to a condition characterized by addiction in relation to some high-fat and high-sugar carbohydrate that leads to clinically significant impairment or distress on several areas of functioning. The Yale Food Addiction Scale 2.0 (YFAS 2.0) has been recently updated to measure FA according to the DSM-5 criteria for substance-related and addictive disorders. This study aimed at validating the Italian version of YFAS 2.0. A sample of 574 Italian university students was involved in this research. Confirmatory Factor Analysis (CFA) and Kuder-Richardson's alpha for dichotomous data were run to evaluate scale structure and reliability. Correlations between YFAS 2.0 and eating psychopathology, binge eating, sleep, and mood symptoms were evaluated. Analogously to the original version, a single factor structure emerged at the CFA. The alpha coefficient was 0.87. Moreover, sound, from moderate to high, correlations were found with other measures. The Italian version of the YFAS 2.0 has demonstrated in a sample of university students to be a useful tool to investigate food addictions. Level of evidence Level V, descriptive study.

  18. Galakontserti Wiedemanni võimlas toetab uhke lavasõu / Jüri-Ruut Kangur

    Index Scriptorium Estoniae

    Kangur, Jüri-Ruut, 1975-

    2005-01-01

    31. juulil toimub Haapsalu Wiedemanni spordihoones filmimuusika kontsert "Gladiaator". Kultusfilmidest tuntud muusikat esitab noortest muusikutest koosnev sajaliikmeline sümfooniaorkester. Muusikat toetab efektne lavashow. Dirigeerib prantslane Thierry Stallano

  19. 2002-IJBCS-Article-Thierry B C Alavo

    African Journals Online (AJOL)

    hp

    intensive d'insecticides chimiques a conduit au développement du phénomène de résistance chez les moustiques ..... Ley et Blaxter, 2002), où l'on rencontre la .... (1990) ont démontré que R. culicivorax ..... Biological Control, 43: 136–143.

  20. Château-Thierry – La Blanchisserie

    OpenAIRE

    Baillieu, Michel

    2013-01-01

    Identifiant de l'opération archéologique : 9254 Date de l'opération : 2007 (EX) Le diagnostic archéologique portait sur une surface assez importante (5 627 m²) pour un aménagement en contexte urbain. Ce projet de construction de deux immeubles de logements initié par la société Logivam SA d’HLM est situé au sud de la rivière de la Marne, juste en bordure de la rive gauche du canal dit de la Fausse Marne. Ce secteur de la ville, peu reconnu archéologiquement jusqu’alors, se trouve en dehors de...

  1. "Gladiaator" pakkus kuulajaile traagelniitideta meelelahutust / Kaie Ilves

    Index Scriptorium Estoniae

    Ilves, Kaie

    2005-01-01

    31. juulil toimub Haapsalu Wiedemanni spordihoones suurejooneline filmimuusika kontsert "Gladiaator". Kultusfilmidest tuntud muusikat esitab noortest muusikutest koosnev sajaliikmeline sümfooniaorkester. Muusikat toetab efektne lavashow. Dirigeerib prantslane Thierry Stallano

  2. Yachting club

    CERN Multimedia

    Yachting club

    2010-01-01

    "New SU" doing very nicely! It seems to me what we most urgently need is a proper name for the "New SU". For a boat that is currently ranking a vey respectable 21st out of 35 in the Swiss Sailing Championships for Surprise, "New Surprise" is not sufficient identification! Check out http://www.cnpully.ch/uploads/media/cs_surprise_s.htm. All congratulations to Thierry and his crew, some old members (we speak chronologically), some newer, one completely new this year.   SUI 702    NEW SURPRISE   BOILEAU Thierry KLUDAS Jana (F1980) DELA ROCHEFORDIERE Antoine (M1957) PROKOFIEV Kirill (M1978) SWOBODA Detlef (M1948)   Still on the subject of the new Surprise, if you have not seen our webpage blog,...

  3. Gender Disparities in Medical Student Research Awards: A Thirteen-Year Study From the Yale School of Medicine.

    Science.gov (United States)

    King, Joseph T; Angoff, Nancy R; Forrest, John N; Justice, Amy C

    2017-11-14

    Instruction in research conduct is currently required, and many U.S. medical schools require students to complete a research project. Each year all Yale School of Medicine (YSM) graduating students submit a research thesis, and ~5% are awarded highest honors. Gender disparities exist in areas related to physician research productivity, including academic rank, research funding, and publications. The authors asked whether gender disparities exist for medical student research. The authors conducted a retrospective review of 1,120 theses submitted by graduating medical students from 2003-2015 at YSM and collected data on gender, mentoring, research type, sponsoring department, and other characteristics. Multivariate logistic regression modeling examined gender differences in medical student research awards. Women authored 50.9% of theses, but earned only 30.9% of highest honors awards (OR 0.41, 95% CI: 0.23, 0.74). Among factors associated with increased receipt of highest honors that differed by gender, men were more likely than women to work with a mentor with a history of 3 or more thesis honorees, take a fifth year of study, secure competitive research funding, undertake an MD-Master of Health Science degree, and conduct laboratory research (for all, P < .001). After adjustment for these factors, and for underrepresented in medicine status and sponsoring department, women remained less likely to receive highest honors (OR 0.51, 95% CI: 0.27, 0.98). Women medical students at YSM were less likely to receive highest honors for medical research. Gender disparities in postgraduate biomedical research success may start during undergraduate medical education.Written work prepared by employees of the Federal Government as part of their official duties is, under the U.S. Copyright Act, a "work of the United States Government" for which copyright protection under Title 17 of the United States Code is not available. As such, copyright does not extend to the contributions of

  4. Do psychological and behavioral factors classified by the West Haven-Yale Multidimensional Pain Inventory (Swedish version) predict the early clinical course of low back pain in patients receiving chiropractic care?

    DEFF Research Database (Denmark)

    Eklund, Erik A; Bergstrom, G.; Bodin, L.

    2016-01-01

    Background: To investigate if psychological and behavioral factors (as determined by the Swedish version of the West Haven-Yale Multidimensional Pain Inventory, MPI-S) can predict the early clinical course of Low Back Pain (LBP). Methods: MPI-S data from patients (18-65 years of age) seeking...... improvement. The chance of "definite improvement", expressed as relative risk (95 % CI) with the AC group as reference, was 1.05 (.87-1.27) for the ID and 1.10 (.93-1.31) for the DYS groups, respectively. The DYS and ID groups reported higher values in pain intensity both at the 1st and the 4th visit....... The proportion of subjects who reported an improvement in pain intensity of 30 % or more (clinically relevant) were 63.5 % AC, 72.0 % ID and 63.2 % DYS. Expressed as relative risk (95 % CI) with the AC group as reference, this corresponded to 1.26 (.91-1.76) for the ID and 1.09 (.78-1.51) for the DYS groups...

  5. Western Indian Ocean Journal of Marine Science: Editorial Policies

    African Journals Online (AJOL)

    Economics - TANZANIA. Thierry LEVITRA. Marine Biology and Mariculture - MADAGASCAR. Blandina LUGENDO. Marine Ecology - TANZANIA. Aviti MMOCHI. Mariculture - TANZANIA. Nyawira MUTHIGA. Marine Ecology and Management - KENYA. Brent NEWMAN. Contamination and Risk Assessment – SOUTH AFRICA.

  6. Assessing the Psychometric Properties of Two Food Addiction Scales

    Science.gov (United States)

    Lemeshow, Adina; Gearhardt, Ashley; Genkinger, Jeanine; Corbin, William R.

    2016-01-01

    Background While food addiction is well accepted in popular culture and mainstream media, its scientific validity as an addictive behavior is still under investigation. This study evaluated the reliability and validity of the Yale Food Addiction Scale and Modified Yale Food Addiction Scale using data from two community-based convenience samples. Methods We assessed the internal and test-retest reliability of the Yale Food Addiction Scale and Modified Yale Food Addiction Scale, and estimated the sensitivity and negative predictive value of the Modified Yale Food Addiction Scale using the Yale Food Addiction Scale as the benchmark. We calculated Cronbach’s alphas and 95% confidence intervals (CIs) for internal reliability and Cohen’s Kappa coefficients and 95% CIs for test-retest reliability. Results Internal consistency (n=232) was marginal to good, ranging from α=0.63 to 0.84. The test-retest reliability (n=45) for food addiction diagnosis was substantial, with Kappa=0.73 (95% CI, 0.48–0.88) (Yale Food Addiction Scale) and 0.79 (95% CI, 0.66–1.00) (Modified Yale Food Addiction Scale). Sensitivity and negative predictive value for classifying food addiction status were excellent: compared to the Yale Food Addiction Scale, the Modified Yale Food Addiction Scale’s sensitivity was 92.3% (95% CI, 64%–99.8%), and the negative predictive value was 99.5% (95% CI, 97.5%–100%). Conclusions Our analyses suggest that the Modified Yale Food Addiction Scale may be an appropriate substitute for the Yale Food Addiction Scale when a brief measure is needed, and support the continued use of both scales to investigate food addiction. PMID:27623221

  7. Dragotsennaja osen / Tatjana Barmakova

    Index Scriptorium Estoniae

    Barmakova, Tatjana

    2004-01-01

    Moefirmade Dior, Yves Saint Laurent (jumestuskunstnik Linda Cantello), Guerlain (kunstnik Olivier Echaudemaison), Shiseido (kunstnik Tom Pecheux) meigikollektsioonidest. Diori, Kenzo ja Thierry Mugleri uutest parfüümidest. "Kenzoairi" parfüümipudeli disainis klaasikunstnik Laura de Santillana

  8. Law, Democracy & Development - Vol 11, No 1 (2007)

    African Journals Online (AJOL)

    Effects on the employment relationship of the insolvency of the employer: A worker perspective · EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Peter Carolus, Thierry Galani Tiemeni, Kurt Ziervogel, 109-120 ...

  9. Annual Symposium, Psychology in the Air Force (5th), 8 April - 10 April 1976

    Science.gov (United States)

    1976-06-01

    effects of having women on board emphasized that they enjoyed working with the women on the USS SANCTUARY. A healthy, coeducational situation existed...1973-1974. Yale University, July 1974. 2. Arnstein, M. B. Coeducation 1972-73. Yale UniversitV, July 1973. 3. Chobot, D. S., Goldberg, P. A., Abramson...Princeton University, April 1973. 8. Wasserman, E. Coeducation 1969-70. Yale University, July 1970. 9. Wasserman, E. Coeducation 1971-72. Yale

  10. Fiktiivne auhinnagala Lõuna-Prantsusmaal II / Madli Pesti

    Index Scriptorium Estoniae

    Pesti, Madli, 1980-

    2009-01-01

    Muljeid tänavusest 63. Avignoni teatrifestivalist. Pikemalt järgmistest etendustest: Krzysztof Warlikowski "(A)pollonia", Claude Regy "Ode Maritime" (Fernando Pessoa poeemi järgi), Frederico Leoni "Yo en el futuro" ("Mina tulevikus"), Thierry Bedard'i "Geko košmaarid" jt.

  11. PS overcomes two serious magnet failures

    CERN Multimedia

    Maximilien Brice

    2003-01-01

    Two magnets (no.'s 6 and 19)and a bus bar connection in the PS were found to be faulty during high-voltage tests at the end of the accelerator shutdown. A five-week repair schedule was quickly devised. A team of mechanics, technicians and engineers worked at full speed to replace the faulty magnets, succeeding in limiting the delay of the accelerators' spring start-up to two weeks. Pictured here are members of the PS team with the replacement no. 6 magnet. From left to right: In the back row, Frédéric Roussel (Transport DBS), Yves Bernard (Transport DBS), Luc Moreno (Cegelec), Thierry Battimanza (Transport DBS), Raymond Brown (AB/ABP), Thomas Zickler (AT/MEL); at the front, Steven Southern (AT/VAC), Thierry Gaidon (Brun & Sorensen), Philippe Vidales (Cegelec), Daniel Aubert (Cegelec), Jerome Cachet (Transport DBS), Jose Manual Gomes de Faria (AT/MEL), Eric Page (AT/VAC).

  12. Prevalence of 'Food Addiction' as Measured with the Yale Food Addiction Scale 2.0 in a Representative German Sample and Its Association with Sex, Age and Weight Categories.

    Science.gov (United States)

    Hauck, Carolin; Weiß, Annegret; Schulte, Erica Marla; Meule, Adrian; Ellrott, Thomas

    2017-01-01

    To assess the prevalence and correlates of addictive-like eating behavior in Germany. The German version of the Yale Food Addiction Scale (YFAS) 2.0 was used to investigate, for the first time, the prevalence of 'food addiction' in a representative sample aged 18-65 years (N = 1,034). The prevalence of 'food addiction' measured by the YFAS 2.0 was 7.9%. Individuals meeting criteria for 'food addiction' had higher BMI and were younger than individuals not meeting the threshold. Underweight (15.0%) and obese (17.2%) individuals exhibited the highest prevalence rate of 'food addiction'. Addictive-like eating was not associated with sex, education level, or place of residence. YFAS 2.0 'food addiction' was met by nearly 8% of the population. There is a non-linear relationship between addictive-like eating and BMI, with the highest prevalence among underweight and obese persons. These findings suggest that 'food addiction' may be a contributor to overeating but may also reflect a distinct phenotype of problematic eating behavior not synonymous with obesity. Further, the elevated prevalence of YFAS 2.0 'food addiction' among underweight individuals may reflect an overlap with eating disorders and warrants attention in future research. © 2017 The Author(s) Published by S. Karger GmbH, Freiburg.

  13. Oma isast kättemaksufilmi teinud kunstnik avas maalinäituse / Kaupo Meiel

    Index Scriptorium Estoniae

    Meiel, Kaupo, 1975-

    2001-01-01

    19. veebr. avas rootsi kunstnik Linda Västrik Pärnu Uue Kunsti Muuseumis oma arvutil tehtud skulptuurikavandite näituse "Valus vaikus", igal paaristunnil saab vaadata ka tema filmi "Isa ja mina". Samas ruumis on väljas ka belgia vaimupuudega kunstniku Thierry Degeyteri maalid

  14. Novotel Xinqiao Aims High

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    One of the oldest properties in China's modem hotel industry, Novotel Xinqiao Beijing, has been a success for 50 years. The hotel is now under the leadership of its second French general manager since its cooperation with the French hotel management group Accor in 2001. Thierry Brinte,

  15. Sajandilõpu jumalad Düsseldorfis

    Index Scriptorium Estoniae

    1999-01-01

    Düsseldorfi Kunsthalles 27. okt.-ni näitus 'Taevas' sajandilõpu iidolitest. Eksponeeritud fotod naisatleetvõimlejatest ja supermodellidest, Thierry Mugleri rõivakollektsioon, Orlani kosmeetilisi näooperatsioone jäädvustavad fotod, Jeff Koonsi klaasist Michael Jacksoni portree, Olga Tobrelutsu maal Leonardo DiCapriost jm.

  16. Oliver Sacks: Our Correspondence About Twins/Twin Research: Vanishing Twins Syndrome; Discordant Sex in MZ Twins; Pregnancy Outcomes in IVF and ICSI Conceived Twins/Print and Media: Superfetated Twins; Twins Discordant for Smoking; Twins in Fashion; Yale University Twin Hockey Players; Conjoined Twin-Visiting Professor.

    Science.gov (United States)

    Segal, Nancy L

    2017-08-01

    The late neurologist and author, Oliver Sacks, published an insightful 1986 review of Marjorie Wallace's book, The Silent Twins, in the New York Times. Taking exception to his assertion about Sir Francis Galton, I wrote a letter to the Times' editor. The letter was unpublished, but it brought a wonderful response from Sacks himself that is reproduced and examined. Next, brief reviews of twin research concerning the vanishing twin syndrome (VTS), discordant sex in a monozygotic (MZ) twin pair, and multiple pregnancy outcomes from assisted reproductive technology (ART) are presented. This section is followed by popular coverage of superfetated twins, smoking-discordant co-twins, twins in fashion, Yale University twin hockey players, and a visiting professor who was a conjoined twin.

  17. Validation of the French version of the yale food addiction scale: an examination of its factor structure, reliability, and construct validity in a nonclinical sample.

    Science.gov (United States)

    Brunault, Paul; Ballon, Nicolas; Gaillard, Philippe; Réveillère, Christian; Courtois, Robert

    2014-05-01

    The concept of food addiction has recently been proposed by applying the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision, criteria for substance dependence to eating behaviour. Food addiction has received increased attention given that it may play a role in binge eating, eating disorders, and the recent increase in obesity prevalence. Currently, there is no psychometrically sound tool for assessing food addiction in French. Our study aimed to test the psychometric properties of a French version of the Yale Food Addiction Scale (YFAS) by establishing its factor structure and construct validity in a nonclinical population. A total of 553 participants were assessed for food addiction (French version of the YFAS) and binge eating behaviour (Bulimic Investigatory Test Edinburgh and Binge Eating Scale). We tested the scale's factor structure (factor analysis for dichotomous data based on tetrachoric correlation coefficients), internal consistency, and construct validity with measures of binge eating. Our results supported a 1-factor structure, which accounted for 54.1% of the variance. This tool had adequate reliability and high construct validity with measures of binge eating in this population, both in its diagnosis and symptom count version. A 2-factor structure explained an additional 9.1% of the variance, and could differentiate between patients with high, compared with low, levels of insight regarding addiction symptoms. In our study, we validated a psychometrically sound French version of the YFAS, both in its symptom count and diagnostic version. Future studies should validate this tool in clinical samples.

  18. Euroopa kaotab positsioone / Thierry Chervel ; tõlk. Ann Must

    Index Scriptorium Estoniae

    Chervel, Thierry

    2005-01-01

    Mitmed Prantsusmaa ja Saksamaa ajakirjandusväljaanded ei avalda oma artikleid Internetis, samas kui Ameerika ning Suurbritannia ajalehed on võrgus kättesaadavad. Autori arvates aitab see kaasa inglise keele domineerimisele. Ettekanne Euroopa kultuuriajakirjade 17. kohtumisel "Kirjasõna vabariik? Kultuuriajakirjad Euroopa avalikus sfääris" Tallinnas 15. mail 2004. aastal

  19. Dr. Janie Merkel is interviewed by Ryan Blum and Janice Friend.

    Science.gov (United States)

    Merkel, Janie

    2007-12-01

    Dr. Janie Merkel is the director of Yale's Chemical Genomics Screening Facility, a high-throughput screening laboratory that is part of the Yale University Center for Genomics and Proteomics. The Screening Facility connects Yale researchers with industry-quality robotic machinery and a diverse group of compound libraries, which have been used successfully to link therapeutic targets with potential therapies.

  20. FOREWORD Foreword

    Science.gov (United States)

    Appourchaux, Thierry

    2011-01-01

    Volume 271 (2011) of the Journal of Physics: Conference Series provides a record of the invited and contributed talks, and of the posters presented at the GONG2010-SoHO24 conference entitled 'A new era of seismology of the Sun and solar-like stars'. The conference was held from 27 June 2010 to 2 July 2010 in Aix-en-Provence, France. More than 120 scientists from all over the world attended the conference. I would like to express my gratitude for the the financial support from the following organisations: Université Paris-Sud; the Centre National d'Etudes Spatiales (CNES); the Programme National des Relations Soleil-Terre (PNST) and the Programme National de Physique Stellaire (PNPS) (both programmes under the umbrella of the Institut National des Sciences de l'Univers, INSU); INSU of the Centre National de la Recherche Scientifique (CNRS); the SoHO project of the European Space Agency (ESA), and the Science Programme of ESA; the Global Oscillations Network Group (GONG); and finally the European Aeronautic Defence and Space Company (EADS). The Scientific Organizing Committee comprised Thierry Appourchaux (chairman, Institut d'Astrophysique Spatiale, Orsay, France), Frank Hill (co-chairman, GONG / National Solar Observatory, Tucson, Arizona, United States), Annie Baglin (Observatoire de Paris-Meudon, France), William Chaplin (University of Birmingham, United Kingdom), Jørgen Christensen-Dalsgaard (Aarhus Universitet, Denmark), Thierry Corbard (Observatoire de la Côte d'Azur, Nice, France), Bernhard Fleck (European Space Agency), Laurent Gizon (Max-Planck-Institut für Sonnensystemforschung, Lindau, Germany), Travis Metcalfe (National Center for Atmospheric Research, Boulder, Colorado, United States), Michael Thompson (Sheffied University, United Kingdom; High Altitude Observatory, Boulder, Colorado, United States) and Jesper Schou (Stanford University, California, United States). The Editorial Committee of these proceedings was composed of Thierry Appourchaux

  1. ELECTIONS TO THE SENIOR STAFF ADVISORY COMMITTEE 1999 (THE NINE)

    CERN Multimedia

    Werner ZAPF; Polling Officer

    1999-01-01

    The votes for the above-mentioned elections were counted in public at 5.00 p.m. on Thursday, 24 June 1999.The results are as follows: Voting roll553Envelopes returned401\t(73%)Invalid votes9Blank3Valid votes389Electoral GroupNameVotesGroup 2AUTIN BrunoBAILEY, RogerGAROBY, RolandVON RUEDEN, Wolfgang6669118 119Group 5aCUTHBERT, JohnKOULBERG, NicolasLAGRANGE, Thierry13864 138The following persons are elected:One in Group 2: Wolfgang VON RUEDEN, ITOne in Group 5a: John CUTHBERT, PE1)Their mandates are for three years.The Committee now consists of these two newly elected members together with:G. Altarelli,D. Blechschmidt,G. Geschonke,O. Gröbner,J. Richards,L. Rolandi andJ. Schinzel.Werner Zapf, Polling Officer1) Given the ex aequo vote between John Cuthbert and Thierry Lagrange, lots were drawn on 25 June 1999 in the presence of the Polling Officer, the two candidates and members of the NINE. The result was in favour of John Cuthbert.

  2. J/ψ production

    Indian Academy of Sciences (India)

    Author Affiliations. François Arleo1 Pol-Bernard Gossiaux1 Thierry Gousset2 Jörg Aichelin2. ECT and INFN, G.C. di Trento, Strada delle Tabarelle, 286, 38050 Villazano, Italy; SUBATECH, Laboratoire de Physique Subatomique et des Technologies Associées, UMR Université de Nantes, IN2P3/CNRS, Ecole des Mines de ...

  3. optical analysis of a hemispheric concentrator with a manual ...

    African Journals Online (AJOL)

    PROF. BARTH EKWEME

    Figure 3: Evolution of the concentration profile with seasons. 146. KY, THIERRY S. M., KAM, SIÉ., DIANDA, ..... GRAPHTEC brand. - A probe (probe A) is placed against the glass window of the receiver to measure the temperature in the focal point. To do this, we follow the light spot indicating the reflection of the sun and ...

  4. Validation of the Spanish Version of the Yale Food Addiction Scale 2.0 (YFAS 2.0 and Clinical Correlates in a Sample of Eating Disorder, Gambling Disorder, and Healthy Control Participants

    Directory of Open Access Journals (Sweden)

    Roser Granero

    2018-05-01

    Full Text Available Aims: Due to the increasing evidence of shared vulnerabilities between addictive behaviors and excessive food intake, the concept of food addiction in specific clinical populations has become a topic of scientific interest. The aim of this study was to validate the Yale Food Addiction Scale (YFAS 2.0 in a Spanish sample. We also sought to explore food addiction and its clinical correlates in eating disorder (ED and gambling disorder (GD patients.Methods: The sample included 301 clinical cases (135 ED and 166 GD, diagnosed according to DSM-5 criteria, and 152 healthy controls (HC recruited from the general population.Results: Food addiction was more prevalent in patients with ED, than in patients with GD and HC (77.8, 7.8, and 3.3%, respectively. Food addiction severity was associated with higher BMI, psychopathology and specific personality traits, such as higher harm avoidance, and lower self-directedness. The psychometrical properties of the Spanish version of the YFAS 2.0 were excellent with good convergent validity. Moreover, it obtained good accuracy in discriminating between diagnostic subtypes.Conclusions: Our results provide empirical support for the use of the Spanish YFAS 2.0 as a reliable and valid tool to assess food addiction among several clinical populations (namely ED and GD. The prevalence of food addiction is heterogeneous between disorders. Common risk factors such as high levels of psychopathology and low self-directedness appear to be present in individuals with food addiction.

  5. Draft Environmental Impact Statement: Peacekeeper Rail Garrison Program

    Science.gov (United States)

    1988-06-01

    Patricia Haldorsen, Senior Technical Editor, Tetra Tech, Inc. B.A., 1982, English Literature, California State University, San Bernardino Years of...Thierry, Word Processing Supervisor, Tetra Tech, Inc. Years of Experience: 6 Patricia A. Turnham, Publications Manager, Tetra Tech, Inc. A.A., 1974...Breiner Mark Barnhard Sharon Breitweiser Barrry J. Barnhart Charles R. Brevik James R. Barr Ronald Brimberry, M.D. Bruce D. Barry Barbara Brinkley Tad

  6. Reference: 435 [Arabidopsis Phenome Database[Archive

    Lifescience Database Archive (English)

    Full Text Available Arabidopsis. 7107 106-9 16936718 2006 Sep Nature Fobis-Loisy Isabelle|Gaude Thierry|Jaillais Yvon|Miège Christine|Rollin Claire ... 435 http://metadb.riken.jp/db/SciNetS_ria224i/cria224u4ria224u16936718i Jaillais Yvon et al. 2006 Sep. Natu...re 443(7107):106-9. Polarized cellular distribution of the phytohormone auxin and i

  7. Dr. Vernon W. Hughes, 81, authority on the subatomic

    CERN Multimedia

    Lavietes, S

    2002-01-01

    "Dr. Vernon W. Hughes, a Yale physicist whose investigation of particles called muons poked holes in standard subatomic theory and provided evidence for the existence of previously undetected matter, died at Yale-New Haven Hospital last Tuesday" (1/2 page).

  8. L'Afrique, nouvel Eldorado du commerce | IDRC - International ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    5 déc. 2013 ... Il est directeur du Perimeter Institute for Theoretical Physics, où il est également titulaire de la chaire Mike and Ophelia Lazaridis Niels Bohr. Thierry Zomahoun, M.B.A., M.Ph., est directeur général de l'AIMS Next Einstein Initiative (AIMS-NEI) et directeur du secrétariat mondial d'AIMS. Cet article a été publié ...

  9. L'Afrique, nouvel Eldorado du commerce | CRDI - Centre de ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    5 déc. 2013 ... Il est directeur du Perimeter Institute for Theoretical Physics, où il est également titulaire de la chaire Mike and Ophelia Lazaridis Niels Bohr. Thierry Zomahoun, M.B.A., M.Ph., est directeur général de l'AIMS Next Einstein Initiative (AIMS-NEI) et directeur du secrétariat mondial d'AIMS. Cet article a été publié ...

  10. Segregating Schools: The Foreseeable Consequences of Tuition Tax Credits.

    Science.gov (United States)

    Yale Law Journal, 1979

    1979-01-01

    Argues that the effect of a proposed tuition tax credit is school segregation, creating serious constitutional objections under the due process clause. A voucher system would avoid these constitutional objections. Available from the Yale Law Journal, 401A Yale Station, New Haven, CT 06520. (Author/IRT)

  11. Xylaria at the Forest Products Laboratory : past, present, and future

    Science.gov (United States)

    Regis B. Miller

    1999-01-01

    This report describes the history and current status of wood collections housed in the Center for Wood Anatomy Research at the Forest Products Laboratory, USDA Forest Service. The collections include the original Madison collection (MADw.) and the collection formerly housed at the Yale School of Forestry, Yale University (...

  12. Information Based Productivity.

    Science.gov (United States)

    Bennett, Scott

    A digital project undertaken last year at Yale (Connecticut) offers an opportunity to explore productivity matters. The project aimed at improving the quality of library support and of student learning in one of the most heavily enrolled undergraduate courses at Yale, "Introduction to the History of Art, from Prehistory to the…

  13. Kohastumus eluks vee ääres / Laura Kuusk

    Index Scriptorium Estoniae

    Kuusk, Laura, 1982-

    2007-01-01

    4. "Ars Baltica" fototriennaal Kumu Kunstimuuseumis kuni 30. IX. Tellervo Kalleineni ja Oliver Kochta-Kalleineni, Alexander Vaindorfi, Coloneli (Thierry Geoffroy) ja Khaled D. Ramadani, Kaspars Goba, Tanja Nellemann Poulseni, Katrin Teesi, Anu Pennaneni, Petra Baueri, Talleiv Taro Manumi (sünd. 1968 Jaapanis, elab Norras), Olga Tshernõsheva, Kristina Inciuraite, Julita Wojciki, Sven Johne, Anna Baumgarti, Arturas Valiauga ja duo J&K (Janne Schäfer, Kristine Agergaard) töödest

  14. ”By the Cake of the Dark Lord!”

    DEFF Research Database (Denmark)

    Cortsen, Rikke Platz

    2015-01-01

    The article uses Stuart Hall’s thoughts on culture and representation in collaboration with Thierry Groensteen’s formal comics theory to analyze how metal is represented in three Nordic comics: Frode Øverli’s Pondus, Lise Myhre’s Nemi, and Perkeros by J.P.Ahonen and K.P. Alare. The study shows...... that metal is a multifacetted concept in these comics and that metal serves various purposes, although notably black metal is consistently ridiculed...

  15. Harvey Cushing’s Ghosts: Death and Hauntings in Modern Medicine

    Science.gov (United States)

    Shin, Paul

    2011-01-01

    The passing of Yale School of Medicine’s 2010 Bicentennial occasions a moment of reflecting on the past, present, and future of medical education and research at Yale and beyond. Last June, a ribbon-cutting ceremony inaugurated the opening of the Cushing Center in the Cushing-Whitney Medical Library. Named after Harvey Cushing, an early 20th-century neurosurgeon and former Yale College alum, the dual education/exhibition space now houses hundreds of gross brain specimens constituting the Cushing Tumor Registry. Originally a personal collection, Cushing donated his numerous medical specimens, photographs, and other medical relics from his deathbed, relinquishing the brains to Yale only under the condition that a suitable space be erected to preserve the many specimens. Some 70 years later and after nearly being destroyed, Cushing’s wish is fully realized: The once desiccated, hidden brains have been painstakingly restored and are now on view in the Cushing Center. The brains express Cushing’s singular and spectral worldview as a surgeon, artist, athlete, soldier, book collector, and historian. PMID:21698039

  16. Harvey Cushing's ghosts: death and hauntings in modern medicine.

    Science.gov (United States)

    Shin, Paul

    2011-06-01

    The passing of Yale School of Medicine's 2010 Bicentennial occasions a moment of reflecting on the past, present, and future of medical education and research at Yale and beyond. Last June, a ribbon-cutting ceremony inaugurated the opening of the Cushing Center in the Cushing-Whitney Medical Library. Named after Harvey Cushing, an early 20th-century neurosurgeon and former Yale College alum, the dual education/exhibition space now houses hundreds of gross brain specimens constituting the Cushing Tumor Registry. Originally a personal collection, Cushing donated his numerous medical specimens, photographs, and other medical relics from his deathbed, relinquishing the brains to Yale only under the condition that a suitable space be erected to preserve the many specimens. Some 70 years later and after nearly being destroyed, Cushing's wish is fully realized: The once desiccated, hidden brains have been painstakingly restored and are now on view in the Cushing Center. The brains express Cushing's singular and spectral worldview as a surgeon, artist, athlete, soldier, book collector, and historian.

  17. Lifetime measurements in the picosecond range: achievements and perspectives

    International Nuclear Information System (INIS)

    Kruecken, R.

    2000-01-01

    Recent developments in the measurement of lifetimes in the picosecond range using the recoil distance method (RDM) are reviewed. Results from recent RDM experiments on superdeformed bands in the mass-190 region, shears, bands in the neutron deficient lead isotopes, and ground state bands in the mass-130 region are presented. New experimental devices for lifetime experiments at Yale, such as the New Yale Plunger Device (N.Y.P.D.), the SPEctrometer for Doppler-shift Experiments at Yale (SPEEDY) and the plans for the gas-filled recoil separator SASSYER are presented. Perspectives for the use of the RDM technique in the study of exotic nuclei and its potential use with radioactive beams are discussed. (author)

  18. Study of the Collective Characteristics of Quarks and Gluons in High Energy Nuclear Collisions. Final technical report. February 15, 1998 - December 31, 1998

    International Nuclear Information System (INIS)

    Manly, Steven L.

    1999-01-01

    During this period the Yale Phobos group funds provided support for closeout of the Yale Phobos DAQ effort and the transition to a new effort on offline software and physics preparedness based at the University of Rochester. The new group at Rochester/BNL looks forward to continuing the work on Phobos and the physics of RHIC

  19. Black holes matter

    DEFF Research Database (Denmark)

    Kragh, Helge Stjernholm

    2016-01-01

    Review essay, Marcia Bartusiak, Black Hole: How an Idea Abandoned by Newtonians, Hated by Einstein, and Gambled On by Hawking Became Loved (New Haven: Yale University Press, 2015).......Review essay, Marcia Bartusiak, Black Hole: How an Idea Abandoned by Newtonians, Hated by Einstein, and Gambled On by Hawking Became Loved (New Haven: Yale University Press, 2015)....

  20. Theoretical nuclear physics at Yale University

    Energy Technology Data Exchange (ETDEWEB)

    1992-12-31

    Brief summaries of past and planned activities in the following areas are given: models of nuclear structure; models of hadronic structure; hot nuclei; chaos in nuclei; reactions and structure; dissipation, diffusion, and collective motion; and modeling equilibrium and nonequilibrium systems.

  1. Yale's "Taliban Man" and Other Tales

    Science.gov (United States)

    Fund, John

    2007-01-01

    In August 2001, the author relates his first encounter with Sayed Rahmatullah Hashimi when he visited the "Wall Street Journal." Sayed Rahmatullah Hashimi was then the ambassador at large and the deputy foreign minister for the Taliban regime of Afghanistan. Ten years before, in 1993, Rahmatullah Hashimi's people tried to blow up the…

  2. A glimpse of the Quaternary monsoon history from India and adjoining seas

    Digital Repository Service at National Institute of Oceanography (India)

    Saraswat, R.; Nigam, R.; Correge, T.

    /plain; charset=UTF-8 1    Author version: Palaeogeogr. Palaeoclimatol. Palaeoecol., vol.397; 2014; 1-6 A glimpse of the Quaternary monsoon history from India and adjoining seas Rajeev Saraswat1, Rajiv Nigam1, Thierry Correge2 1 National... and radionuclide (210Pb) analyses to understand past environmental changes from the sediment cores collected from mudflat regions of central west coast of India. A significant shift in sediment characteristics is observed post 1980, probably in response...

  3. France at CERN, from 23 to 25 September 2003

    CERN Multimedia

    Maximilien Brice

    2003-01-01

    From left to right: Jean-Claude Brisson, ILO, Robert Aymar, designated CERN Director General, Françoise Le Moign, Assistant General Consul at Geneva, Alain Guillouët, Head of the economic mission in Switzerland, French Embassy, Thierry Boquien, Ubifrance, French agency for international development of companies, Bernard Frois, Director of the Department for Energy, Transport, and Environment of the French Ministry for Research and New Technologies, Claude Détraz, CERN Director for Fixed Targets and Future Programmes.

  4. Empreinte génomique parentale et petits ARN non-codants

    OpenAIRE

    Seitz , Hervé

    2004-01-01

    Cavaillé Jérôme, Chargé de recherche, CNRS, Toulouse : directeur de thèse Charlier Carole, Professeur associé, Université de Liège : rapporteur Clerc Philippe, Chef de laboratoire, Institut Pasteur, Paris : rapporteur Cribbs David, Professeur, Université Toulouse III : président du jury Forné Thierry, Chargé de recherche, CNRS, Montpellier : examinateur Voinnet Olivier, Chargé de recherche, CNRS, Strasbourg : examinateur; Genomic imprinting results in a differential expression of both alleles...

  5. Educational "Goodwill": Measuring the Intangible Assets at Highly Selective Private Colleges and Universities. NBER Working Paper No. 17412

    Science.gov (United States)

    Nurnberg, Peter; Schapiro, Morton; Zimmerman, David

    2011-01-01

    In this paper we utilize data on the head-to-head loss rate for students accepted at Williams College, but who opt to enroll elsewhere. For example, we employ data that measure the fraction of students admitted to Williams and to Amherst (or Harvard or Yale, etc.) but who opt to attend Amherst (or Harvard or Yale, etc.) instead of Williams. We…

  6. The state of Europe's environment

    International Nuclear Information System (INIS)

    Lavoux, Th.; Desaunay, C.

    2007-01-01

    The deterioration of the world's environment, and in particular the ever greater likelihood of global warming, is the subject of an increasing number of studies. But what is known about the environmental situation in Europe? Despite the political impasse that the European Union is currently in, what are the individual member states doing about the environment? The EU's policy on the environment dates back to 1973, and is remarkable as one of the few areas where the member states appear to accept restrictive agreements unanimously and try afterwards to respect them. Furthermore, the activities of the European Environment Agency seem not to attract the criticisms levelled at most other EU institutions. As Thierry Lavoux explains in this article, the EU's measures have made it possible to stop using both lead in petroleum products and chlorofluorocarbons. The latest challenge for the member states is to reduce their emissions of greenhouse gases (especially by meeting the Kyoto criteria) at the same time that emissions generated by the transport and construction sectors are growing steadily. In addition, he stresses, the member states need to be concerned by threats to their ecosystems from urban sprawl, massive use of pesticides and irrigation, and over-fishing... Lastly, says Thierry Lavoux, the EU members must quickly apply their minds to ways of making their agriculture more sustainable and limiting their production of toxic chemicals. (author)

  7. Development of a Novel Therapeutic Paradigm Utilizing a Mammary Gland-Targeted, Bin-1 Knockout Mouse Model

    Science.gov (United States)

    2007-03-01

    Thierry-Mieg et al. AceView: identification and functional annotation of cDNA- supported genes in higher organisms— Homo sapiens gene INDO, encoding...stimulating function of RhoB. J Biol Chem 1997; 272:15591–4. 25. Routhier EL , Donover PS, Prendergast GC. hob1+, the homolog of Bin1 in fission yeast, is...tumours on inoculation of EL -4 thymoma or B16 melanoma cells due to an increased tumour-specific CTL response85. TGFβ suppression of tumour-specific

  8. Influence of specific obsessive-compulsive symptom dimensions on strategic planning in patients with obsessive-compulsive disorder.

    Science.gov (United States)

    Pinto, Paula Sanders Pereira; Iego, Sandro; Nunes, Samantha; Menezes, Hemanny; Mastrorosa, Rosana Sávio; Oliveira, Irismar Reis de; Rosário, Maria Conceição do

    2011-03-01

    This study investigates obsessive-compulsive disorder patients in terms of strategic planning and its association with specific obsessive-compulsive symptom dimensions. We evaluated 32 obsessive-compulsive disorder patients. Strategic planning was assessed by the Rey-Osterrieth Complex Figure Test, and the obsessive-compulsive dimensions were assessed by the Dimensional Yale-Brown Obsessive-Compulsive Scale. In the statistical analyses, the level of significance was set at 5%. We employed linear regression, including age, intelligence quotient, number of comorbidities, the Yale-Brown Obsessive-Compulsive Scale score, and the Dimensional Yale-Brown Obsessive-Compulsive Scale. The Dimensional Yale-Brown Obsessive-Compulsive Scale "worst-ever" score correlated significantly with the planning score on the copy portion of the Rey-Osterrieth Complex Figure Test (r = 0.4, p = 0.04) and was the only variable to show a significant association after linear regression (β = 0.55, t = 2.1, p = 0.04). Compulsive hoarding correlated positively with strategic planning (r = 0.44, p = 0.03). None of the remaining symptom dimensions presented any significant correlations with strategic planning. We found the severity of obsessive-compulsive symptoms to be associated with strategic planning. In addition, there was a significant positive association between the planning score on the copy portion of the Rey-Osterrieth Complex Figure Test copy score and the hoarding dimension score on the Dimensional Yale-Brown Obsessive-Compulsive Scale. Our results underscore the idea that obsessive-compulsive disorder is a heterogeneous disorder and suggest that the hoarding dimension has a specific neuropsychological profile. Therefore, it is important to assess the peculiarities of each obsessive-compulsive symptom dimension.

  9. One of the two end-cap vacuum chambers for the CMS experiment has been completed.

    CERN Multimedia

    Maximilien Brice

    2005-01-01

    This 7.5-metre-long cone-shaped object is the fruit of many years' development and its machining and assembly were performed with the utmost precision. Part of the team involved in the design and production of the end-cap vacuum chamber for CMS, standing behind the completed segment. Picture 02 from left to right : Thierry Tardy (TS/MME), Luigi Leggiero (TS/MME), Patrick Lepeule (AT/VAC), Gérard Faber (ETH Zürich), Stefano Bongiovani (CINEL Project Manager), Giuseppe Foffano (TS/MME) and Marc Thiebert (TS/MME).

  10. Worlds within Worlds: Audiences, Jargon, and North American Comics Discourse

    Directory of Open Access Journals (Sweden)

    Craig Fischer

    2010-09-01

    Full Text Available Let me begin by describing four recent acts of comics criticism, all connected to each other like dominoes falling: The first act: In 2007, the University Press of Mississippi published an English-language translation of Thierry Groensteen’s The System of Comics (Système de la bande dessinée, 1999. In their foreword to System, translators Bart Beaty and Nick Nguyen anticipate obstacles to the American reception of Groensteen’s ideas, arguing that American scholars are unfamiliar with the “do...

  11. Yakouba ou le passage d’un rite à l’autre

    OpenAIRE

    Martinez-Verdier, Marie-Louise

    2010-01-01

    Comme toutes les institutions, l’éducation qui permet aux jeunes d’entrer dans la culture et de définir leur identité, est fondée sur le sacrifice violent. Elle peut cependant distancer progressivement cette violence fondatrice, à certaines conditions. L’homme est un animal rituel, et il ne sort des rites violents que par des rites moins violents. L’article fait une lecture anthropologique de Yakouba, album de Thierry DEDIEU, Le Seuil 1994. Il souligne comment à l’occasion de son initiation t...

  12. Clarifying the Rules for Targeted Killing: An Analytical Framework for Policies Involving Long-Range Armed Drones

    Science.gov (United States)

    2016-09-08

    tightly con- trolled such groups need to be, and how committed, geographi- cally focused, and frequent their attacks, for an “armed conflict” to exist and...Forever War,” YaleGlobal Online , May 7, 2013 (as of July 8, 2016:http://yaleglobal.yale.edu/content/how-end-forever-war). 30 Johnson, 2012. According to...intellectual property is provided for noncommercial use only. Unauthorized posting of this publication online is prohibited. Permission is given to

  13. Elite Settlements and Democracy in Latin America: The Dominican Republic and Peru

    Science.gov (United States)

    1989-08-01

    Social Indicators, volume 2, 3d edition, (New Haven: Yale Wuiversity Press, 1983), pg. 48. UOn a scale from one to seven, one being the greatest...Handbook of Political and Social Indicators, volume 1, 3d edition, (New Haven: Yale University Press, 1983), pg. 209. 107 (12% in 1977) was organized.53...Westview Press, 1988. Si. Lima: Impresora La Republica S.A. Smith, Michael. Political correspondent for Lima Times during Constituent Assembly. Lima, Peru

  14. The Fukushima accident: radiological consequences and first lessons. Proceedings; L'accident de Fukushima: consequences radiologiques et premiers enseignements. Recueil des presentations

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2012-02-15

    This document brings together the available presentations given at the conference organised by the French society of radiation protection about the Fukushima accident, its radiological consequences and the first lessons learnt. Sixteen presentations (slides) are compiled in this document and deal with: 1 - Accident progress and first actions (Thierry Charles, IRSN); 2 - Conditions and health monitoring of the Japanese intervention teams (Bernard Le Guen, EDF); 3 - The Intra Group action after the Fukushima accident (Michel Chevallier, Groupe Intra; Frederic Mariotte, CEA); 4 - Processing of effluents (Georges Pagis, Areva); 5 - Fukushima accident: impact on the terrestrial environment in Japan (Didier Champion, IRSN); 6 - Consequences of the Fukushima accident on the marine environment (Dominique Boust, IRSN); 7 - Territories decontamination perspectives (Pierre Chagvardieff, CEA); 8 - Actions undertaken by Japanese authorities (Florence Gallay, ASN); 9 - Japanese population monitoring and health stakes (Philippe Pirard, InVS); 10 - Citizen oversight actions implemented in Japan (David Boilley, ACRO); 11 - Implementation of ICRP's (International Commission on Radiological Protection) recommendations by Japanese authorities: first analysis (Jacques Lochard, CIPR); 12 - Control of Japan imported food stuff (David Brouque, DGAL); 13 - Questions asked by populations in France and in Germany (Florence-Nathalie Sentuc, GRS; Pascale Monti, IRSN); 14 - Labour law applicable to French workers working abroad (Thierry Lahaye, DGT); 15 - Protection of French workers working in Japan, Areva's experience (Patrick Devin, Areva); 16 - Fukushima accident experience feedback and post-accident nuclear doctrine (Jean-Luc Godet, ASN)

  15. The Fukushima accident: radiological consequences and first lessons. Proceedings

    International Nuclear Information System (INIS)

    2012-02-01

    This document brings together the available presentations given at the conference organised by the French society of radiation protection about the Fukushima accident, its radiological consequences and the first lessons learnt. Sixteen presentations (slides) are compiled in this document and deal with: 1 - Accident progress and first actions (Thierry Charles, IRSN); 2 - Conditions and health monitoring of the Japanese intervention teams (Bernard Le Guen, EDF); 3 - The Intra Group action after the Fukushima accident (Michel Chevallier, Groupe Intra; Frederic Mariotte, CEA); 4 - Processing of effluents (Georges Pagis, Areva); 5 - Fukushima accident: impact on the terrestrial environment in Japan (Didier Champion, IRSN); 6 - Consequences of the Fukushima accident on the marine environment (Dominique Boust, IRSN); 7 - Territories decontamination perspectives (Pierre Chagvardieff, CEA); 8 - Actions undertaken by Japanese authorities (Florence Gallay, ASN); 9 - Japanese population monitoring and health stakes (Philippe Pirard, InVS); 10 - Citizen oversight actions implemented in Japan (David Boilley, ACRO); 11 - Implementation of ICRP's (International Commission on Radiological Protection) recommendations by Japanese authorities: first analysis (Jacques Lochard, CIPR); 12 - Control of Japan imported food stuff (David Brouque, DGAL); 13 - Questions asked by populations in France and in Germany (Florence-Nathalie Sentuc, GRS; Pascale Monti, IRSN); 14 - Labour law applicable to French workers working abroad (Thierry Lahaye, DGT); 15 - Protection of French workers working in Japan, Areva's experience (Patrick Devin, Areva); 16 - Fukushima accident experience feedback and post-accident nuclear doctrine (Jean-Luc Godet, ASN)

  16. Dissecting the Imperceptible

    OpenAIRE

    Kramer-Mallordy, Antje

    2012-01-01

    Encouraged by his museum experience as curator at the Mamco in Geneva, Thierry Davila offers us the recent history of the flipside of art, the one played out on the borderlines of the perceptible, where extreme tenuousness is presented as the actual motif of creation. His book, which is an offshoot of his doctoral thesis, supervised by Eric Michaud and submitted in 2008 at the EHESS, and is devoted to the creation of the barely-visible, draws up a subtle report showing great flair within a hi...

  17. Natural and artificial ultraviolet radiation and skin cancer risk: what's new? Proceedings of the SFRP Non-ionizing radiation section round table

    International Nuclear Information System (INIS)

    Douki, Thierry; Boniol, Mathieu; Dore, Jean-Francois

    2015-12-01

    The Non-ionizing radiation section of the French Society of Radiation Protection (SFRP) organized a technical meeting on the current knowledge of UV mutagenicity mechanisms, on professional exposures and on the risks linked with artificial tanning and their prevention. This document brings together the 3 available presentations (slides) of the talks given at the meeting: 1 - UV induction of DNA photoproducts: recent data (Thierry DOUKI, CEA Grenoble); 2 - Professional exposure to UV radiations (Mathieu BONIOL, IPRI); 3 - Artificial tanning: a major but avoidable public health problem (Jean-Francois DORE, Centre de Recherche en Cancerologie)

  18. The operational performance of the Yale ESTU

    Indian Academy of Sciences (India)

    nal and control system have greatly increased its capability and reliability. Today ... Flow schemes were simplified; an electric heater as well as safety ... installed, the original MP injector was retained except for a new pre-acceleration power.

  19. Task A: Yale Accelerator Users Group (YAUG)

    International Nuclear Information System (INIS)

    Adair, R.K.; Sandweiss, J.; Schmidt, M.

    1993-01-01

    This report discusses the following topics: Yaug collider detector program; E-791: continued study of heavy flavors at TPL; Hadroproduction of charm and beauty; Search for composite objects produced in relativistic heavy ion collisions; and high energy physics computer facility

  20. Book Reviews

    Directory of Open Access Journals (Sweden)

    William R. Roff

    1970-07-01

    Full Text Available - Jane Bunnag, Hans-Dieter Evers, Loosely structured social systems: Thailand in comparative perspective. Cultural Report Series no. 17, Yale University Southeast Asia Studies. New Haven 1969. 148 pp. - L. Sluimers, Milton E. Osborne, The French presence in Cochin-China and Cambodia: Rule and response (1859-1905. Cornell University Press, Ithaca and London 1970. XVIII + 379 pp. - H.J. Duller, G.L. Hicks, The Indonesian economy, 1950-1965; met een supplement tot 1967. Bibliographical Series No. 9, South-East Asia Studies, Yale University 1967. 248 p., n.p., G. McNicoll (eds. - J.W. de Vries, A. Mörzer Bruyns, Kamus singkatan dan akronim yang dipergunakan di Indonesia/Glossary of abbreviations and acronyms used in Indonesia, Ichtiar, Djakarta 1970. - William R. Roff, Abdul Majid Mohamed Mackeen, Contemporary Islamic legal organization in Malaya. Monograph Series No. 13. Yale University Southeast Asia Studies, New Haven, 1969. vii + 79 + 55 pp.

  1. Genetic variants in FBN-1 and risk for thoracic aortic aneurysm and dissection.

    Science.gov (United States)

    Iakoubova, Olga A; Tong, Carmen H; Rowland, Charles M; Luke, May M; Garcia, Veronica E; Catanese, Joseph J; Moomiaie, Remo M; Sotonyi, Peter; Ascady, Gyorgy; Nikas, Demitrios; Dedelias, Panagiotis; Tranquilli, Maryann; Elefteriades, John A

    2014-01-01

    A recent genome wide association study (GWAS) by LeMaire et al. found that two single nucleotide polymorphisms (SNPs), rs2118181 and rs10519177 in the FBN-1 gene (encoding Fibrillin-1), were associated with thoracic aortic dissection (TAD), non-dissecting thoracic aortic aneurysm (TAA), and thoracic aortic aneurysm or dissection (TAAD); the largest effect was observed for the association of rs2118181 with TAD. We investigated whether rs2118181 and rs10519177 were associated with TAD, TAA, and TAAD in the Yale study. The genotypes of rs2118181 and rs10519177 were determined for participants in the Yale study: 637 TAAD cases (140 TAD, 497 TAA) and 275 controls from the United States, Hungary, and Greece. The association of the genotypes with TAD, TAA and TAAD were assessed using logistic regression models adjusted for sex, age, study center and hypertension. In the Yale study, rs2118181 was associated with TAD: compared with non-carriers, carriers of the risk allele had an unadjusted odds ratio for TAD of 1.80 (95% CI 1.15-2.80) and they had odds ratio for TAD of 1.87 (95% CI 1.09-3.20) after adjusting for sex, age, study center and hypertension. We did not find significant differences in aortic size, a potential confounder for TAD, between rs2118181 risk variant carriers and non-carriers: mean aortic size was 5.56 (95% CI: 5.37-5.73) for risk variant carriers (CC+CT) and was 5.48 (95% CI: 5.36-5.61) for noncarriers (TT) (p = 0.56). rs2118181 was not associated with TAA or TAAD. rs10519177 was not associated with TAD, TAA, or TAAD in the Yale study. Thus, the Yale study provided further support for the association of the FBN-1 rs2118181SNP with TAD.

  2. Thierry De Putter, a geologist faced to the ''irrational'' fear of radioactive wastes

    International Nuclear Information System (INIS)

    Putter, Th. de; Pivot, A.

    2004-01-01

    The author analyses the origins of the irrational fear the public feels concerning the disposal of radioactive wastes in deep geological layers. This fear seems to be linked to the positive image of the earth that has been built for millenniums in all humane civilizations, according to it the earth appears as a universal, pure and prolific mother. The burial of radioactive wastes might be considered in an unconscious way as a direct and permanent threat to the integrity of the earth. In fact the earth is not so fragile, it has already undergone catastrophes worse than these that are looming like climate changing or extinction of species, but what is true is that humane civilizations settled on its surface are very fragile. Irrational fear might be an acute and unconscious awareness of this fragility. (A.C.)

  3. Fukushima, 4 years after. Proceedings of the technical day

    International Nuclear Information System (INIS)

    Champion, Didier; Charles, Thierry; Renaud, Philippe; Fievet, Bruno; Besnus, Francois; Tichauer, Michael; Lecomte, Jean-Francois; Lebaron-Jacobs, Laurence; Menetrier, Florence; Piroux, Jean-Christophe; Schneider, Thierry; Godet, Jean-Luc

    2015-03-01

    Three years after the 2012 meeting of the French Society of Radiation Protection (SFRP) devoted to the Fukushima accident, the SFRP organized a new technical meeting to take stock of the actual situation in Japan. The program comprises 5 topical sessions dealing with: the accident, the status of the facility and its fate, the terrestrial and marine environmental impacts, the human health impacts and the preventive actions, the remedial actions in contaminated territories, and the post-accident management of territories, populations and foodstuffs. This document brings together the abstracts and the presentations (slides) of the different talks given at the meeting: 1 - The Chernobyl and Fukushima accidents: common points and differences (Didier CHAMPION, SFRP); 2 - Fukushima Dai-ichi: present day situation and fate of the facilities (Thierry CHARLES, IRSN); 3 - The Fukushima accident impact on the terrestrial environment and the related doses (Philippe RENAUD, IRSN); 4 - The Fukushima accident impact on the marine environment (Bruno FIEVET, IRSN); 5 - Short-term health effects and implementation of the long-term population monitoring (Laurence LEBARON-JACOBS, CEA); 6 - Radiations and thyroid cancer risk (Florence MENETRIER, CEA); 7 - Decontamination wastes management (Francois BESNUS, IRSN); 8 - Solutions offered by Areva for the cleansing of the Fukushima site (Jean-Christophe PIROUX, AREVA); 9 - Questions about wastes management in post-accident situation (Michael TICHAUER, IRSN); 10 - Experts involvement to the population (Thierry SCHNEIDER, CEPN); 11 - Management of local foodstuffs (Jean-Francois LECOMTE, IRSN); 12 - Lessons learnt at the national and international scale (Jean-Luc GODET, ASN)

  4. Educational "Goodwill": Measuring the Intangible Assets at Highly Selective Private Colleges and Universities

    OpenAIRE

    Peter Nurnberg; Morton Schapiro; David Zimmerman

    2011-01-01

    In this paper we utilize data on the head-to-head loss rate for students accepted at Williams College, but who opt to enroll elsewhere. For example, we employ data that measure the fraction of students admitted to Williams and to Amherst (or Harvard or Yale, etc.) but who opt to attend Amherst (or Harvard or Yale, etc.) instead of Williams. We then model this head-to-head loss rate using data from a variety of sources. A better understanding of the head-to-head loss rate can assist an institu...

  5. Interview with Harold McGee

    OpenAIRE

    Mac Con Iomaire, Máirtín

    2016-01-01

    Harold McGee was born on the East coast of America but grew up in Chicago. He writes about the chemistry of food and cooking. He took up this odd vocation after studies at the California Institute of Technology and at Yale University, where he wrote a doctoral thesis with the prophetic title "Keats and the Progress of Taste." After several years as a literature and writing instructor at Yale, he decided to practice what he'd been teaching, and write a book about the science of everyday life. ...

  6. "Objects and Places” – Photographs by Alan Trachtenberg


    Directory of Open Access Journals (Sweden)

    Géraldine Chouard

    2011-04-01

    Full Text Available  “Black-and-white images of diverse scenes in America—ranging from a Mississippi ���ghost” town to rooftops in Pennsylvania to an upper New York state racetrack—are featured in a new exhibition of photographs by Yale professor Alan Trachtenberg at the Henry Koerner Center for Emeritus Faculty. The exhibit, titled “Objects and Places,” is a selection of 22 photographs that Trachtenberg made over the past 30 years using a large-format (8×10 camera.” [Excerpt from the Yale Daily Bulletin]The foll...

  7. Reflections on a life in biomedicine: leading change.

    Science.gov (United States)

    Nabel, Elizabeth G

    2013-09-01

    Dr. Elizabeth Nabel delivered the following presentation as the Lee E. Farr Lecturer on May 7, 2013, which served as the culmination of the annual Student Research Day at Yale School of Medicine. Dr. Nabel is President of the Brigham and Women's Hospital in Boston, Massachusetts, and Professor of Medicine at Harvard Medical School. Her lecture to Yale medical students portrayed her own personal and professional journey through medicine as a series of opportunities. Dr. Nabel focused on the roles and responsibilities of physicians to recognize need and to make change through focused advocacy.

  8. Taking the Plunge: Next Steps in Engaged Learning: Project Kaleidoscope-Connecticut Conference of Independent Colleges Conference for Science Educators.

    Science.gov (United States)

    Frederick, Jennifer

    2010-09-01

    College and university science educators from across Connecticut gathered at Yale's West Campus in April 2010 for a Project Kaleidoscope (PKAL) program entitled "Taking the Plunge: Next Steps in Engaged Learning." Funded by the National Science Foundation (NSF) and co-sponsored by the Connecticut Conference of Independent Colleges (CCIC) and Yale's McDougal Graduate Teaching Center, the event was the latest in a PKAL series of one-day conferences aimed at equipping science, technology, engineering, and math (STEM) instructors with effective approaches to engaging students and training future scientists.

  9. Research on and in medical education.

    Science.gov (United States)

    Panter, Michaela S

    2011-09-01

    Dr. George Lister of the University of Texas Southwestern Medical Center delivered the Lee E. Farr Lecture on Student Research Day on May 9, 2011. This day focused on the dissertation work of Yale School of Medicine MD students, whose research opportunities for prospective physicians were recently examined and critiqued by Yale's Committee to Promote Student Interest in Careers as Physician Scientists. Lister's talk served to highlight the importance of communication between the laboratory and the clinic in optimizing diagnostics and treatments, effectively affirming the validity of the Committee's objectives. Copyright © 2011.

  10. Total facing the new oil and gas situation

    International Nuclear Information System (INIS)

    Desmarest, Th.

    2006-01-01

    Total produces oil and gas in more than thirty countries, and contributes to warding off energy shortfalls through its exploration and investment programmes, through its expertise at the leading edge of hydrocarbon technology, and by its attention to the interests of host countries. However, the combination of unflagging demand and growing dependence vis-a-vis the principal producing regions is a source of tension and of risks which call for a much greater discipline in energy consumption and a diversification of energy sources. Thierry Desmarest, the Chairman and Managing Director of Total, gives his view of the new energy situation. (author)

  11. Adam Smith et le “républicanisme”

    Directory of Open Access Journals (Sweden)

    Alexandra HYARD

    2003-10-01

    Full Text Available Je remercie Pierre Lurbe et Ann Thomson pour leurs remarques. Je tiens également à remercier Thierry Demals pour son aide précieuse. Néanmoins, je reste seule responsable des éventuelles erreurs contenues dans ce travail.Introduction Smith semble avoir toujours été en théorie un républicain, et il a sûrement eu le vrai esprit d’un républicain dans son amour de toute liberté rationnelle. (Rae 124 Par cette phrase, Rae nous livre son opinion sur une des questions relatives à Adam Smith (1723-1...

  12. Enjeux et pratiques documentaires en conservation-restauration, perspectives pour la recherche 

    Directory of Open Access Journals (Sweden)

    Marie-Hélène Breuil

    2010-11-01

    Full Text Available IntroductionConsacrées à la documentation des œuvres, ces deux journées d’étude qui se sont tenues les 14 et 15 octobre 2010 comportaient quatre sessions : définition, production, gestion et utilisation. Elles ont permis de faire le point et d’échanger sur les outils techniques, les contenus, l’accès ainsi que la conservation de cette documentation. Dans son introduction, Thierry Lalot, directeur du CRPB (Université Paris 1, a souligné la volonté d’ouvrir des perspectives pour la recherche e...

  13. Chapitre III. Le diocèse de Liège dans l’empire germanique

    OpenAIRE

    Kupper, Jean-Louis

    2013-01-01

    « Illos vero legatos a latere Romani episcopi exeuntes et ad ditanda marsupia discurrentes omnino refuta mus »Sigebert, Ep. Leod. adv. Pasch., Libelli, t. II, p. 459 (1102). Lorsque, sous l’épiscopat de Théoduin, l’abbé Thierry Ier de Saint-Hubert, accusé d’avoir placé son abbaye sous la juridiction immédiate de Saint-Pierre, proposa simplement à ses adversaires d’aller débattre l’affaire en cour de Rome, l’archidiacre Boson lui rétorqua qu’une pareille procédure léserait gravement les droits...

  14. A Visual Analog Scale to assess anxiety in children during anesthesia induction (VAS-I): Results supporting its validity in a sample of day care surgery patients.

    Science.gov (United States)

    Berghmans, Johan M; Poley, Marten J; van der Ende, Jan; Weber, Frank; Van de Velde, Marc; Adriaenssens, Peter; Himpe, Dirk; Verhulst, Frank C; Utens, Elisabeth

    2017-09-01

    The modified Yale Preoperative Anxiety Scale is widely used to assess children's anxiety during induction of anesthesia, but requires training and its administration is time-consuming. A Visual Analog Scale, in contrast, requires no training, is easy-to-use and quickly completed. The aim of this study was to evaluate a Visual Analog Scale as a tool to assess anxiety during induction of anesthesia and to determine cut-offs to distinguish between anxious and nonanxious children. Four hundred and one children (1.5-16 years) scheduled for daytime surgery were included. Children's anxiety during induction was rated by parents and anesthesiologists on a Visual Analog Scale and by a trained observer on the modified Yale Preoperative Anxiety Scale. Psychometric properties assessed were: (i) concurrent validity (correlations between parents' and anesthesiologists' Visual Analog Scale and modified Yale Preoperative Anxiety Scale scores); (ii) construct validity (differences between subgroups according to the children's age and the parents' anxiety as assessed by the State-Trait Anxiety Inventory); (iii) cross-informant agreement using Bland-Altman analysis; (iv) cut-offs to distinguish between anxious and nonanxious children (reference: modified Yale Preoperative Anxiety Scale ≥30). Correlations between parents' and anesthesiologists' Visual Analog Scale and modified Yale Preoperative Anxiety Scale scores were strong (0.68 and 0.73, respectively). Visual Analog Scale scores were higher for children ≤5 years compared to children aged ≥6. Visual Analog Scale scores of children of high-anxious parents were higher than those of low-anxious parents. The mean difference between parents' and anesthesiologists' Visual Analog Scale scores was 3.6, with 95% limits of agreement (-56.1 to 63.3). To classify anxious children, cut-offs for parents (≥37 mm) and anesthesiologists (≥30 mm) were established. The present data provide preliminary data for the validity of a Visual

  15. The MOVES (Motor tic, Obsessions and compulsions, Vocal tic Evaluation Survey): cross-cultural evaluation of the French version and additional psychometric assessment.

    Science.gov (United States)

    Jalenques, Isabelle; Guiguet-Auclair, Candy; Derost, Philippe; Joubert, Pauline; Foures, Louis; Hartmann, Andreas; Muellner, Julia; Rondepierre, Fabien

    2018-03-01

    The Motor tic, Obsessions and compulsions, Vocal tic Evaluation Survey (MOVES) is a self-report scale suggested as a severity scale for tics and related sensory phenomena observed in Gilles de la Tourette syndrome (GTS) and recommended as a screening instrument by the Committee on Rating Scale Development of the International Parkinson's Disease and Movement Disorder Society. To cross-culturally adapt a French version of the MOVES and to evaluate its psychometric properties. After the cross-cultural adaptation of the MOVES, we assessed its psychometric properties in 53 patients aged 12-16 years and in 54 patients aged 16 years and above: reliability and construct validity (relationships between items and scales), internal consistency and concurrent validity with the Yale Global Tic Severity Scale (YGTSS) and the Children's Yale-Brown Obsessive-Compulsive Scale (CY-BOCS) or the auto-Yale-Brown scale. The results showed very good acceptability with response rates greater than 92%, good internal consistency (Cronbach's alpha ranging from 0.62 and 0.89) and good test-retest reliability (ICCs ranging from 0.59 to 0.91). Concurrent validity with the YGTSS, CY-BOCS and auto-Yale-Brown scales showed strong expected correlations. The cut-off points tested for diagnostic performance gave satisfactory values of sensitivity, specificity, and positive and negative predictive values. Our study provides evidence of the good psychometric properties of the French version of the MOVES. The cross-cultural adaptation of this specific instrument will allow investigators to include French-speaking persons with GTS aged 12 years and over in national and international collaboration research projects.

  16. Advanced accelerator test facility-Final report for the period 9/1/2010 - 8/31/2013

    Energy Technology Data Exchange (ETDEWEB)

    Hirshfield, Jay [Yale Univ., New Haven, CT (United States)

    2014-10-27

    This final report summarizes results achieved in the Beam Physics Laboratory at Yale University during the period 9/1/2010 – 8/31//2013, under DoE grant DE-FG02-07 ER 41504. During the period covered by this report, notable progress in technical consolidation of facilities in the Yale Beam Physics Laboratory has occurred; and theory, design, and fabrication for future experiments have been carried out. In the period covered by this grant, 29 scientific publications based on this work and related topics have appeared in the archival literature. Titles, authors, and citations are listed in Section V of this report.

  17. Emergency pediatric anesthesia - accessibility of information.

    Science.gov (United States)

    King, Hannah; Pipe, Georgina E M; Linford, Sarah L; Moppett, Iain K; Armstrong, James A M

    2015-03-01

    Emergency pediatric situations are stressful for all involved. Variation in weight, physiology, and anatomy can be substantial and errors in calculating drugs and fluids can be catastrophic. To evaluate the reliability of information resources that anesthetic trainees might use when faced with common pediatric emergencies. Anesthetic trainees from a single UK deanery were recruited and timed while they identified 18 predetermined pieces of information from three Advanced Pediatric Life Support (APLS) scenarios. The two most popular smartphone applications identified from a previous survey, PaedsED (PaedsED. iED limited, Version 1.0.8, Updated March 2011. ©2009) and Anapaed (AnaPaed. Thierry Girard, Version 1.4.2, Updated Nov 2, 2012. ©Thierry Girard), the British National Formulary for Children (cBNF) and trainee's inherent knowledge were compared with a local, check-list style, handbook of pediatric emergency algorithms - Pediatric Anesthetic Emergency Data sheets (PAEDs). Twenty anesthetic trainees were recruited. The fastest source of information was the trainees own knowledge (median 61 s, IQR 51-83 s). Second fastest was PAEDs (80, [59-110] s), followed by PaedsED (84, [65-111]). The most accurate source overall was PaedsED (100, [83-100]) although the accuracy varied between scenarios. The handbook was rated as the most popular resource by the trainees. Although fastest, trainees own knowledge is inaccurate, highlighting the need for additional, rapidly accessible, information. Of the two smartphone applications, PaedsED proved to be fast, accurate, and more popular, while Anapaed was accurate but slow to use. The PAEDs handbook, with its checklist-style format, was also fast, accurate and rated the most popular information source. © 2014 John Wiley & Sons Ltd.

  18. Du « chamanisme primitif »

    OpenAIRE

    Stépanoff, Charles

    2014-01-01

    Françoise Aubin a consacré à notre ouvrage, Le chamanisme de Sibérie et d’Asie centrale, coécrit avec Thierry Zarcone, un compte rendu qui, quoique dans l’ensemble élogieux, formule une critique sévère à propos du traitement du chamanisme sibérien (ASSR 2013, 164). Les reproches qui me sont adressés, puisque je suis l’auteur de ces passages, sont émaillés d’inexactitudes, d’imprécisions et de stéréotypes. On pourrait mettre ces erreurs sur le compte d’une lecture trop rapide, cependant les po...

  19. A Conversation with Karl K. Turekian

    Science.gov (United States)

    Turekian, Karl K.; Cochran, J. Kirk

    2012-01-01

    Editors' Note Each year, the editorial board invites a distinguished member of the oceanographic community to contribute a prefatory chapter; this year, we were delighted when Karl Turekian, Sterling Professor of Geology and Geophysics at Yale, accepted our invitation. Over the course of a long and productive career, Dr. Turekian has pursued his interests in marine and atmospheric geochemistry by using natural radioactive and radiogenic isotopes to study Earth's evolution and the impacts of global change. He has also directed both the Center for the Study of Global Change at Yale and the Yale Institute for Biospheric Studies. In this interview, conducted by his former student Kirk Cochran, Dr. Turekian tells the story of his early career and discusses some of the major scientific challenges and opportunities faced along the way. His personal account of the rise of geochemistry is a charming story of how chance events and personalities impact scientific careers. His technical insight into the future of this field is illuminating, particularly for scientific outsiders who appreciate the central role of geochemistry in discerning and understanding patterns of global change. Craig A. Carlson and Stephen J. Giovannoni, Editors [Figure: see text

  20. Validation of three compulsive buying scales on an Italian sample.

    Science.gov (United States)

    Tommasi, Marco; Busonera, Alessandra

    2012-12-01

    Compulsive shopping is an impulse control disorder that produces psychological distress. Appropriate measurement scales of compulsive buying are important to identify compulsive buyers. Three compulsive buying scales (Faber and O'Guinn scale, Edwards scale, Yale and Brown scale) were tested in an Italian sample composed of 438 participants randomly selected from the general population. Self-report questionnaires measured psychiatric dysfunctions and personality traits. The data confirmed that high anxiety, obsessive-compulsive dysfunctions, depression, psychoticism, and low self-esteem were associated with inappropriate shopping. The Faber and O'Guinn scale and Edwards Scale are appropriate for surveys, while the Yale and Brown scale are more appropriate for clinical diagnosis of psychological dependences.

  1. From the Catalog to the Book on the Shelf: Building a Mapping Application for Vufind

    Directory of Open Access Journals (Sweden)

    Kathleen Bauer

    2012-06-01

    Full Text Available At Yale University Library (YUL, recorded reference transactions revealed that after finding a book in the catalog patrons had difficulty knowing how to use the call number to find the book on the shelf. The Library created a mobile service to help locate the call number in the library stacks. From any call number of a book in Sterling Memorial Library at YUL, a map will be displayed which highlights that call number’s general area on a floor in the stacks. YUL introduced the mapping application in Yufind, a catalog in place at Yale since 2008 which is based on Vufind.

  2. PathScore: a web tool for identifying altered pathways in cancer data.

    Science.gov (United States)

    Gaffney, Stephen G; Townsend, Jeffrey P

    2016-12-01

    PathScore quantifies the level of enrichment of somatic mutations within curated pathways, applying a novel approach that identifies pathways enriched across patients. The application provides several user-friendly, interactive graphic interfaces for data exploration, including tools for comparing pathway effect sizes, significance, gene-set overlap and enrichment differences between projects. Web application available at pathscore.publichealth.yale.edu. Site implemented in Python and MySQL, with all major browsers supported. Source code available at: github.com/sggaffney/pathscore with a GPLv3 license. stephen.gaffney@yale.edu. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

  3. Thierry De Putter, a geologist faced to the ''irrational'' fear of radioactive wastes; Thierry De Putter, un geologue face a la peur ''irrationnelle'' des dechets radioactifs

    Energy Technology Data Exchange (ETDEWEB)

    Putter, Th. de [Musee Royal de l' Afrique Centrale, Geologie Isotopique, Tervuren (Belgium); Pivot, A. [Paris-10 Univ., Sociologue, Ladyss/NSS, Maison Max Weber, 92 - Nanterre (France)

    2004-06-01

    The author analyses the origins of the irrational fear the public feels concerning the disposal of radioactive wastes in deep geological layers. This fear seems to be linked to the positive image of the earth that has been built for millenniums in all humane civilizations, according to it the earth appears as a universal, pure and prolific mother. The burial of radioactive wastes might be considered in an unconscious way as a direct and permanent threat to the integrity of the earth. In fact the earth is not so fragile, it has already undergone catastrophes worse than these that are looming like climate changing or extinction of species, but what is true is that humane civilizations settled on its surface are very fragile. Irrational fear might be an acute and unconscious awareness of this fragility. (A.C.)

  4. Adding motivational interviewing and thought mapping to cognitive-behavioral group therapy: results from a randomized clinical trial Adicionando a entrevista motivacional e o mapeamento cognitivo à terapia cognitivo-comportamental em grupo: resultados de um ensaio clínico randomizado

    Directory of Open Access Journals (Sweden)

    Elisabeth Meyer

    2010-03-01

    Full Text Available OBJECTIVE: Recent factor-analytic studies of obsessive-compulsive disorder identified consistent symptom dimensions. This study was designed in order to observe which obsessive compulsive symptom dimensions could be changed by adding two individual sessions of motivational interviewing and thought mapping of cognitive-behavioral group therapy using a randomized clinical trial. METHOD: Forty outpatients with a primary diagnosis of obsessive-compulsive disorder were randomly assigned to receive cognitive-behavioral group therapy (control group or motivational interviewing+thought mapping plus cognitive-behavioral group therapy. To evaluate changes in symptomdimensions, the Dimensional Yale-Brown Obsessive-Compulsive Scale was administered at baseline and after treatment. RESULTS: At post-treatment, there were statistically significant differences between cognitive-behavioral group therapy and motivational interviewing+thought mapping+cognitivebehavioral group therapy groups in the mean total Dimensional Yale-Brown Obsessive-Compulsive Scale score, and in the contamination and aggression dimension score. Hoarding showed a statistical trend towards improvement. CONCLUSION: These findings suggest that adding motivational interviewing+thought mapping to cognitive-behavioral group therapy can facilitate changes and bring about a decrease in the scores in different obsessive-compulsive disorder symptom dimensions, as measured by the Dimensional Yale-Brown Obsessive-Compulsive Scale. Nonetheless, additional trials are needed to confirm these results.OBJETIVO: Recentes estudos utilizando análise fatorial no transtorno obsessivocompulsivo identificaram dimensões consistentes dos sintomas. Este estudo foi delineado para observar quais dimensões dos sintomas obsessivo-compulsivos podem ser modificadas adicionando duas sessões individuais de entrevista motivacional e mapeamento cognitivo à terapia cognitivo-comportamental em grupo usando um ensaio cl

  5. Razón y amor en la teología medieval incipiente: Aproximación desde la confluencia de las fuentes griegas y latinas

    Directory of Open Access Journals (Sweden)

    Anneliese Meis

    2002-01-01

    Full Text Available El presente estudio escoje un período de gran envergadura teológica y excepcionalmente sensible al problema razón y amor. En el siglo XII se va gestando la subjetividad moderna, de tanta relevancia para la Teología, pero, sobre todo, se produce aquella confluencia de fuentes latinas y griegas, que como problema requiere máxima atención, ya que su recepción patrística medieval es vital para la búsqueda de la verdad a través de la ciencia. Se estudian siete autores que remontan al siglo XII: -Hildegard von Bingen, Guillermo de St. Thierry, Ricardo de San Víctor-, pero tres le preceden: -Gregorio Magno, Juan Escoto Eriúgena, Anselmo de Canterbury- y uno los complementa: Buenaventura. La elección de estos autores ha permitido seguir de cerca la articulación del problema, su contextualización y las soluciones novedosas, de gran riqueza antropológica teológicaThis study selects a period of great theological depth and particularty sensitive to the issue of reason and love. The modern subjectivity, which has had enormous relevance for Theology, started to germinate during the XII century; the times of the convergence of the Latin and Greek sources. This required much attention, as their reception by the medieval patristic is essential for a proper search of the truth through the science. The article focuses on seven authors who date from the XII century. Hildegard von Binger, Willian of St. Thierry, Richard of Saint Victor, who are preceded by Gregory the Greta, John Scotus Eriungena, Anselm of Canterbury and Bonaventure. The selecction of these authors allows a close articulation of the problem, its contextualisation and novel solutions of great theological and anthropological richness

  6. Gas Warfare in World War I. The 3rd. Division at Chateau Thierry, July 1918

    Science.gov (United States)

    1959-07-01

    I hvt ’.o 1, 17 Jun (Vb, i p. 35 - 36’. 1Jnf.-D>in -i. 10. 1andý’er:Divu i -@Una 5O~fg opv ~lGe vns me., 44 %~ Aw sw1 .~.g P.. 9.s KAi,, .I P LAM... indoors (where delay in masking or escaping to the open was almost certain to rqsult in casualties]. Shell fire and a general sense of insecurity

  7. Strategie della conoscenza nella riflessione di Guglielmo di S. ThierryAmor incapibilem capit, incomprehensibilem comprehendit

    OpenAIRE

    Rossini, Marco

    2008-01-01

    Il problema della visio Dei: si intende comprendere cosa Dio sia, non chi sia. Fondamentale è l'analogia con la struttura della conoscenza sensibile, caratterizzata dall'identificazione fra soggetto conoscente e oggetto conosciuto. L'amore, inteso come sensus animae, opera per mezzo di una conoscenza identificante attraverso una modificazione del sentimento, anche se con una fondamentale differenza rispetto agli altri sensi, in quanto essenzialmente caratterizzato dalla libertà. La declinazio...

  8. Fundamentals of physics II electromagnetism, optics, and quantum mechanics

    CERN Document Server

    Shankar, R

    2016-01-01

    R. Shankar, a well-known physicist and contagiously enthusiastic educator, was among the first to offer a course through the innovative Open Yale Course program. His popular online video lectures on introductory physics have been viewed over a million times. In this second book based on his online Yale course, Shankar explains essential concepts, including electromagnetism, optics, and quantum mechanics. The book begins at the simplest level, develops the basics, and reinforces fundamentals, ensuring a solid foundation in the principles and methods of physics. It provides an ideal introduction for college-level students of physics, chemistry, and engineering; for motivated AP Physics students; and for general readers interested in advances in the sciences.

  9. Kinetic measurements on the silicates of the Yucca Mountain potential repository. Final report for October 1994--September 1995

    International Nuclear Information System (INIS)

    Barnes, H.L.; Wilkin, R.T.

    1995-08-01

    This Final Report includes a summary and discussion of results obtained under this project on the solubilities in subcritical aqueous solutions of Mont St. Hilaire analcime, Wikieup analcime, and Castle Creek Na-clinoptilolite. Also included here are the methods and results of hydrothermal flow-through experiments designed to measure the rates of Na-clinoptilolite dissolution and precipitation at 125 degree C. In this report, high-temperature solubility measurements made in our lab are integrated and discussed along with the low-temperature measurements made at Yale University. The final report prepared by the group at Yale University (Lasaga et al.) includes a synthesis of dissolution rate measurements made between 25 degree and 125 degree C on the Na-clinoptilolite

  10. Conference | From Mars to the Multiverse | By Lord Martin Rees | 3 July

    CERN Document Server

    2014-01-01

    This unique conference is given for the Diplomatic Club of Geneva. It is open to the participants of the European Week of Astronomy and Space Science (EWASS 2014) held in Geneva from 30 June to 4 July, 2014. The academic community of the University of Geneva and CERN is also welcome.   The lecture will be preceded by an allocution by the President of the Diplomatic Club, Luzius Wasescha, and by Prof. Thierry Courvoisier, President of the European Astronomical Society and of the Swiss Academy of Sciences. A cocktail will be served at the end of the event. Registration required: RSVP by 26 June 2014 to clubdiplomatique@fondationpourgeneve.ch

  11. High-gradient two-beam electron accelerator

    Energy Technology Data Exchange (ETDEWEB)

    Hirshfield, Jay L. [Omega-P, Inc., New Haven, CT (United States)

    2014-11-04

    The main goal for this project was to design, build, and evaluate a detuned-cavity, collinear, two-beam accelerator structure. Testing was to be at the Yale University Beam Physics Laboratory, under terms of a sub-grant from Omega-P to Yale. Facilities available at Yale for this project include a 6-MeV S-band RF gun and associated beam line for forming and transporting a ~1 A drive beam , a 300 kV beam source for use as a test beam, and a full panoply of laboratory infrastructure and test equipment. During the first year of this project, availability and functionality of the 6-MeV drive beam and 300 kV test beam were confirmed, and the beam line was restored to a layout to be used with the two-beam accelerator project. Major efforts during the first year were also focused on computational design and simulation of the accelerator structure itself, on beam dynamics, and on beam transport. Effort during the second year was focussed on building and preparing to test the structure, including extensive cold testing. Detailed results from work under this project have been published in twelve archival journal articles, listed in Section IV of the technical report.

  12. Edward A. Bouchet

    Science.gov (United States)

    Mickens, R. E.

    2002-04-01

    Edward A. Bouchet was the first African American to receive the doctorate in any field of knowledge in the United States and that area was physics. He was granted the degree in 1876 from Yale University making him at that time one of the few persons to hold the physics doctorate from an American university. His prior education included the Hopkins Grammar School and Yale College (BA in 1874). After Yale, Bouchet taught mathematics, physics, and chemistry for over twenty-five years at the Institute for Colored Youth in Philadelphia. During the following two decades, he was employed in positions ranging from high school principal to employment by the federal government. Bouchet played a significant role in the education of African Americans through his teaching and mentoring activities. He was one among a small group of African Americans who achieved advanced training and education within decades of the American civil war. These individuals provided direction, leadership, and role models for what eventually became the civil/human rights movements. The year 2001 marks the 125th celebration of his receiving the doctorate. We present details of his life and career with an emphasis on the influence of the political and social forces exerted on him by society.

  13. Girls' Science Investigations (GSI) New Haven: Evaluating the Impact

    Science.gov (United States)

    Knodell, Claire; Fleming, Bonnie

    2009-05-01

    Girls' Science Investigations (GSI) New Haven seeks to empower the girls of today to shape the science of tomorrow. Funded by the NSF and Yale University and held at Yale, this program was designed to motivate, empower, and interest middle school girls in developing the skills required to pursue a career in science during a day-long investigation of the session's featured topic in science. Yale students and female professors act as mentors and guide younger girls through an environment for understanding and exploring various disciplines of science through hands-on activities in a laboratory setting. GSI strives to close the gap between males and females one action-packed Saturday at a time. This paper evaluates the success of the program. Student participant evaluations over the past 2 years coupled with student testimony and GSI coordinator, instructors', and volunteers' interviews allowed for an analysis of GSI's ability to inspire girls to pursue careers in science. The data indicates that a majority of girls who attended the program were more inclined to continue their study of science. The positive results are detailed in the following paper which points to the hands-on activities and enthusiasm of instructors as integral to the program's success.

  14. Kultuur ja geopoliitika / Immanuel Wallestein ; interv. Rein Raud, tõlk. Kaarel Tarand

    Index Scriptorium Estoniae

    Wallestein, Immanuel

    2008-01-01

    Intervjuu Yale'i ülikooli professoriga, kes peatub teemadel, mis puudutavad Nõukogude Liidu kokkuvarisemist, võimalikku Kirde-Aasia alianssi, Venemaa edasist arengut, etnilisuse probleeme, Euroopa kultuurilist hoiakut ja poliitilist integratsiooni

  15. Salaselts saab presidendi koha / koost. Virgo Kruve

    Index Scriptorium Estoniae

    2004-01-01

    Yale'i ülikooli salaseltsi "Skull and Bones" mõjust Ameerika poliitikale, presidentide George Bush seeniori ja George W. Bushi kuulumisest mainitud ühingusse. Telesaate "60 minutit" materjalide põhjal

  16. Local Relation Map: A Novel Illumination Invariant Face Recognition Approach

    Directory of Open Access Journals (Sweden)

    Lian Zhichao

    2012-10-01

    Full Text Available In this paper, a novel illumination invariant face recognition approach is proposed. Different from most existing methods, an additive term as noise is considered in the face model under varying illuminations in addition to a multiplicative illumination term. High frequency coefficients of Discrete Cosine Transform (DCT are discarded to eliminate the effect caused by noise. Based on the local characteristics of the human face, a simple but effective illumination invariant feature local relation map is proposed. Experimental results on the Yale B, Extended Yale B and CMU PIE demonstrate the outperformance and lower computational burden of the proposed method compared to other existing methods. The results also demonstrate the validity of the proposed face model and the assumption on noise.

  17. Centrifugal stretching along the ground state band of 168Hf

    International Nuclear Information System (INIS)

    Costin, A.; Pietralla, N.; Reese, M.; Moeller, O.; Ai, H.; Casten, R. F.; Heinz, A.; McCutchan, E. A.; Meyer, D. A.; Qian, J.; Werner, V.; Dusling, K.; Fitzpatrick, C. R.; Guerdal, G.; Petkov, P.; Rainovski, G.

    2009-01-01

    The lifetimes of the J π =4 + , 6 + , 8 + , and 10 + levels along the ground state band in 168 Hf were measured by means of the recoil distance Doppler shift (RDDS) method using the New Yale Plunger Device (NYPD) and the SPEEDY detection array at Wright Nuclear Structure Laboratory of Yale University. Excited states in 168 Hf were populated using the 124 Sn( 48 Ti,4n) fusion evaporation reaction. The new lifetime values are sufficiently precise to clearly prove the increase of quadrupole deformation as a function of angular momentum in the deformed nucleus 168 Hf. The data agree with the predictions from the geometrical confined β-soft (CBS) rotor model that involves centrifugal stretching in a soft potential

  18. Neurologic Complications of Smallpox Vaccination

    Directory of Open Access Journals (Sweden)

    J Gordon Millichap

    2003-06-01

    Full Text Available Smallpox and smallpox vaccination is reviewed from the Departments of Neurology, Yale University School of Medicine, New Haven, CT, and University of New Mexico School of Medicine, Albuquerque.

  19. 78 FR 13054 - Announcement of the Board of Directors for the National Environmental Education Foundation

    Science.gov (United States)

    2013-02-26

    ... join the current Board members which include: JL Armstrong (NEEF Vice Chair), National Manger, Toyota... Business School and a bachelor's degree in History from Yale University. She speaks Spanish, French and...

  20. At R806

    CERN Multimedia

    CERN PhotoLab

    1976-01-01

    The Brookhaven CERN-Saclay-Syracuse-Yale Collaboration studied large transverse momentum phenomena with transition radiation detectors and liquid argon calorimeters. Here Italo Mannelli and Christine Kourkoumelis. Italo Mannelli and Christine Kourkoumelis

  1. Nangia, Prof. Ashwini

    Indian Academy of Sciences (India)

    . Ashwini Ph.D. (Yale), FRSC, FNA, FNASc. Date of birth: 10 November 1960. Specialization: Crystal Engineering, Supramolecular Chemistry and Polymorphism Address: School of Chemistry, University of Hyderabad, Hyderabad 500 046, A.P.

  2. Acoustic Neuroma Educational Video

    Medline Plus

    Full Text Available ... Hospital University of California, Irvine A.N.S.R.S. Study Yale University Vanderbilt University Mayo Clinic Patient Registry Caregivers Public Webinars Patient Stories Keywords Shop ANA Discussion Forum ...

  3. Asymptomatic multinodular splenoma (splenic hamartoma in a child with sickle cell anemia

    Directory of Open Access Journals (Sweden)

    Elenga N

    2017-07-01

    Full Text Available Narcisse Elenga,1 Sylvain Labbé,2 Nicolas Leduc,2 Anicet Sika,1 Emma Cuadro,1 Laurence Long,1 Falucar Njuieyon,1 Rémi Kom-Tchameni,1 Thierry Basset1 1Department of Pediatrics and Pediatric Surgery, Pediatric Medicine and Surgery, 2Pathological Anatomy Department, Cayenne Hospital, Cayenne Cedex, French Guiana Abstract: Splenoma is a rare and benign malformation usually fortuitously diagnosed during imaging, surgery or, unfortunately, at autopsy. Although splenoma was first described in 1861, its association with hematological pathology is a very unusual condition in children. We report the case of an asymptomatic splenoma in an 8-year-old boy with sickle cell anemia, whose diagnosis was confirmed after conventional splenectomy. Keywords: multinodular splenoma, child, sickle cell anemia, conventional splenectomy

  4. President Ilves visiidil Prantsusmaal

    Index Scriptorium Estoniae

    2008-01-01

    Ingl. k. lüh. lk. 9, pealk.: Ilves, Sarkozy meet. President Toomas Hendrik Ilves kohtus 7. aprillil 2008 Pariisis Elysée palees Prantsusmaa presidendi Nicolas Sarkozyga, kellega arutati NATO tippkohtumise tulemusi, Prantsusmaa Euroopa Liidu eesistumise prioriteete, Euroopa Liidu ühise energia- ja naabruspoliitika küsimusi. Eesti riigipea kohtus veel Prantsusmaa välispoliitika ajakirjanike klubiga (Association de la Presse Diplomatique), Prantsusmaa välisministri Bernard Kouchner'iga, Rahvusassamblee Euroopa Liidu delegatsiooni presidendi Pierre Lequillier'i ja senaator Denis Badré'ga, kes on ühtlasi Senati Prantsuse-Balti sõprusgrupi esimees. Visiidi lõpetas kohtumine Prantsusmaa Välispoliitika Instituudi (Institut Francais des Relations Internationales) presidendi Thierry de Montbrial'iga. Vabariigi President töövisiidil Pariisis 6.-8.04.2008

  5. Untitled

    African Journals Online (AJOL)

    Growth and Flexibility of Government Tax Revenue: The Cameroon. Experience. ... Agrowth equation was also established to see the impact of government fiscal expan- sion on ..... Musgrave, R. (1984), Fiscal Systems, New Haven,. Yale.

  6. Efficacy of Glutamate Modulators in Tic Suppression: A Double-Blind, Randomized Control Trial of D-serine and Riluzole in Tourette Syndrome.

    Science.gov (United States)

    Lemmon, Monica E; Grados, Marco; Kline, Tina; Thompson, Carol B; Ali, Syed F; Singer, Harvey S

    2015-06-01

    It has been hypothesized that glutamatergic transmission may be altered in Tourette syndrome. In this study, we explored the efficacy of a glutamate agonist (D-serine) and antagonist (riluzole) as tic-suppressing agents in children with Tourette syndrome. We performed a parallel three-arm, 8-week, double-blind, randomized placebo-controlled treatment study in children with Tourette syndrome. Each child received 6 weeks of treatment with D-serine (maximum dose 30 mg/kg/day), riluzole (maximum dose 200 mg/day), or placebo, followed by a 2-week taper. The primary outcome measure was effective tic suppression as determined by the differences in the Yale Global Tic Severity Scale score; specifically, the total tic score and the combined score (total tic score + global impairment) between treatment arms after 6 weeks of treatment. Mann-Whitney U tests were performed to analyze differences between each group and the placebo group. Twenty-four patients (males = 21, ages 9-18) enrolled in the study; one patient dropped out before completion. Combined Yale Global Tic Severity Scale score and total tic scores improved in all groups. The 6-week mean percent improvement of the riluzole (n = 10), D-serine (n = 9), and placebo (n = 5) groups in the combined Yale Global Tic Severity Scale score were 43.7, 39.5, and 30.2 and for total tic scores were 38.0, 25.0, and 34.0, respectively. There were no significant differences in Yale Global Tic Severity Scale score or total tic score, respectively, between the riluzole and placebo (P = 0.35, 0.85) or D-serine and placebo (P = 0.50, 0.69) groups. Tics diminished by comparable percentages in the riluzole, D-serine, and placebo groups. These preliminary data suggest that D-serine and riluzole are not effective in tic suppression. Copyright © 2015 Elsevier Inc. All rights reserved.

  7. The Brazilian Research Consortium on Obsessive-Compulsive Spectrum Disorders: recruitment, assessment instruments, methods for the development of multicenter collaborative studies and preliminary results.

    Science.gov (United States)

    Miguel, Euripedes Constantino; Ferrão, Ygor Arzeno; Rosário, Maria Conceição do; Mathis, Maria Alice de; Torres, Albina Rodrigues; Fontenelle, Leonardo Franklin; Hounie, Ana Gabriela; Shavitt, Roseli Gedanke; Cordioli, Aristides Volpato; Gonzalez, Christina Hojaij; Petribú, Kátia; Diniz, Juliana Belo; Malavazzi, Dante Marino; Torresan, Ricardo C; Raffin, Andréa Litvin; Meyer, Elisabeth; Braga, Daniela T; Borcato, Sonia; Valério, Carolina; Gropo, Luciana N; Prado, Helena da Silva; Perin, Eduardo Alliende; Santos, Sandro Iêgo; Copque, Helen; Borges, Manuela Corrêa; Lopes, Angélica Prazeres; Silva, Elenita D da

    2008-09-01

    To describe the recruitment of patients, assessment instruments, implementation, methods and preliminary results of The Brazilian Research Consortium on Obsessive-Compulsive Spectrum Disorders, which includes seven university sites. This cross-sectional study included a comprehensive clinical assessment including semi-structured interviews (sociodemographic data, medical and psychiatric history, disease course and comorbid psychiatric diagnoses), and instruments to assess obsessive-compulsive (Yale-Brown Obsessive-Compulsive Scale and Dimensional Yale-Brown Obsessive-Compulsive Scale), depressive (Beck Depression Inventory) and anxious (Beck Anxiety Inventory) symptoms, sensory phenomena (Universidade de São Paulo Sensory Phenomena Scale), insight (Brown Assessment Beliefs Scale), tics (Yale Global Tics Severity Scale) and quality of life (Medical Outcome Quality of Life Scale Short-form-36 and Social Assessment Scale). The raters' training consisted of watching at least five videotaped interviews and interviewing five patients with an expert researcher before interviewing patients alone. The reliability between all leaders for the most important instruments (Structured Clinical Interview for DSM-IV, Dimensional Yale-Brown Obsessive-Compulsive Scale, Universidade de São Paulo Sensory Phenomena Scale) was measured after six complete interviews. Inter-rater reliability was 96%. By March 2008, 630 obsessive-compulsive disorder patients had been systematically evaluated. Mean age (+/-SE) was 34.7 (+/-0.51), 56.3% were female, and 84.6% Caucasian. The most prevalent obsessive compulsive symptom dimensions were symmetry and contamination. The most common comorbidities were major depression, generalized anxiety and social anxiety disorder. The most common DSM-IV impulsive control disorder was skin picking. The sample was composed mainly by Caucasian individuals, unmarried, with some kind of occupational activity, mean age of 35 years, onset of obsessive

  8. Primary maternal preoccupation revisited: circuits, genes, and the ...

    African Journals Online (AJOL)

    QuickSilver

    2003-05-08

    May 8, 2003 ... Child Study Center,Yale University School of Medicine, New Haven, Connecticut .... importance of parental marital adjustment, self-esteem, and social .... paired with respect to nursing, nest building, or maternal aggression.53.

  9. HIV/AIDS infected mothers' experience of a group intervention to ...

    African Journals Online (AJOL)

    UP User

    2016-05-11

    May 11, 2016 ... Department of Pediatrics, Yale University School of Medicine, New Haven, .... child's social support structures, the HIV-associ- ..... Building emphatic skills in elementary .... http://www.unaids.org/sites/default/files/en/media/.

  10. Kiirreageerimistoad. Manifest, mida viiakse ka ellu = Emergency Rooms. A Manifesto put into Action / Thierry Geoffroy, Colonel

    Index Scriptorium Estoniae

    Geoffroy, Thierry, 1961-

    2006-01-01

    Rindereportaaži meetod kunstis - töid luuakse kiirelt ja reaalajas nagu meedias, iga päev vahetuvatel näitustel kommenteeritakse sama päeva uudiseid. Kiirreageerimistoad New Yorgis, Kopenhaagenis. Kiirreageerimistoa formaat

  11. EtiEsE BEsluitnEming volgEns 1 johannEs

    African Journals Online (AJOL)

    Binne die raamwerke word die aard van die etiese nadenke dan ook verstaan. ... 6 sien, byvoorbeeld, Brown (1979), schnackenburg (1984), Klauck (1991), strecker ...... The origins of Christian morality: The first two centuries. new haven: Yale.

  12. Review of Amanda E. Herbert, Female Alliances: Gender, Identity, and Friendship in Early Modern Britain

    Directory of Open Access Journals (Sweden)

    Angela Rehbein

    2015-03-01

    Full Text Available Review of Amanda E. Herbert, Female Alliances: Gender, Identity, and Friendship in Early Modern Britain. New Haven: Yale UP, 2014. xi, 256 pages: illustrations; 24 cm. ISBN 978-0-300-17740-4.

  13. Reproductive coercion and intimate partner violence among rural ...

    African Journals Online (AJOL)

    AJRH Managing Editor

    Disease Epidemiology, Yale School of Public Health, New Haven, CT, USA, Center for ... Study findings underscore the importance of reducing IPV in ..... mental health30 of Ivorian women. ... coercion may be underreported, due to stigma. In.

  14. Changing Anthropology, Changing Society

    Science.gov (United States)

    Varughese, Heather

    2009-01-01

    Fifty years after the founding of the field of medical anthropology, the Society for Medical Anthropology of the American Anthropological Association held its first independent meeting on September 24-27, 2009, at Yale University. PMID:20027281

  15. effect of habitat fragmentation on diversity and abundance of nesting

    African Journals Online (AJOL)

    cw

    Department of Zoology and Wildlife Conservation, University of Dar es ... Keywords: fragmentation, nesting birds, thickets, campus of the University of Dar es ... 43(1), 2017 ..... Yale University Press, ... bird species in urban parks: Effects of park.

  16. Acoustic Neuroma Educational Video

    Medline Plus

    Full Text Available ... Research Back Keck Medicine of USC Massachusetts General Hospital University of California, Irvine A.N.S.R.S. Study Yale University Vanderbilt University Mayo Clinic Patient Registry Caregivers Public Webinars Patient Stories Keywords ...

  17. Prevalence of food addiction and its relationship to body mass index

    African Journals Online (AJOL)

    Alaa Youssef Ahmed

    is recently measured by the Yale Food Addiction Scale (YFAS). It was speculated ... Egypt is one of the highest African countries in the prevalence of obesity. Aim: Estimation .... Ethics of the World Medical Association (Declaration of Helsinki).

  18. Richard Kelly: Pioneirismo na iluminação da arquitetura moderna

    Directory of Open Access Journals (Sweden)

    Fernanda Brito Bandeira

    2018-04-01

    Full Text Available Livros resenhado: NEUMANN, Dietrich; STERN, Robert A. M. The structure of light: Richard Kelly and the illumination of modern architecture. New York: Yale University Press, 2010, 214 p. ISBN: 978-0-300-16370-4

  19. Risk factor assessment in high-risk, bacillus Calmette–Guérin-treated, non-muscle-invasive bladder cancer

    Directory of Open Access Journals (Sweden)

    Holz S

    2017-09-01

    Full Text Available Serge Holz,* Simone Albisinni,* Jacques Gilsoul, Michel Pirson, Véronique Duthie, Thierry Quackels, Marc Vanden Bossche, Thierry Roumeguère Department of Urology, Erasme Hospital, Université libre de Bruxelles, Belgium *These authors contributed equally to this work Objective: To assess the risk factors associated with recurrence, progression and survival in high-risk non-muscle-invasive bladder cancer (NMIBC patients treated with bacillus Calmette–Guérin (BCG and validate the European Organization for Research and Treatment of Cancer (EORTC and Spanish Urological Club for Oncological Treatment (CUETO scores.Patients and methods: We retrospectively analyzed all BCG-treated NMIBC patients from 1998 to 2012. Multiple variables were tested as risk factors for recurrence-free survival and progression-free survival (PFS. Variables included age, sex, grade, stage, tumor size, number of tumors, carcinoma in situ (CIS, recurrence status, BCG strain used, smoking status, use of re-staging transurethral resection and use of single immediate postoperative instillation. We also tested the accuracy of EORTC and CUETO scores in predicting recurrence and progression.Results: Overall, 123 patients were analyzed. Median (interquartile range follow-up was 49 months. The 5-year overall survival, cancer-specific survival, recurrence-free survival and PFS were 75.0%, 89.3%, 59.4% and 79.2%, respectively. On univariate analysis, multiple tumors (≥3, concomitant CIS and smoking influenced recurrence. Regarding progression, multiple tumors, concomitant CIS and Connaught strain (vs Tice negatively influenced PFS on univariate and multivariate analyses were independent prognostic factors. CUETO scores were accurate, with a slight overestimation, while EORTC score was not predictive of recurrence or progression.Conclusion: In this study, CIS and tumor multiplicity were unfavorable predictors of recurrence and progression in patients with NMIBC receiving BCG

  20. Perfectionism in anorexia nervosa: variation by clinical subtype, obsessionality, and pathological eating behavior.

    Science.gov (United States)

    Halmi, K A; Sunday, S R; Strober, M; Kaplan, A; Woodside, D B; Fichter, M; Treasure, J; Berrettini, W H; Kaye, W H

    2000-11-01

    The purpose of this study was to examine the role of perfectionism as a phenotypic trait in anorexia nervosa and its relevance across clinical subtypes of this illness. The Multidimensional Perfectionism Scale and the perfectionism subscale of the Eating Disorder Inventory were administered to 322 women with a history of anorexia nervosa who were participating in an international, multicenter genetic study of anorexia nervosa. All participants were additionally interviewed with the Yale-Brown Obsessive Compulsive Scale and the Yale-Brown-Cornell Eating Disorder Scale. Mean differences on dependent measures among women with anorexia nervosa and comparison subjects were examined by using generalized estimating equations. Persons who had had anorexia nervosa had significantly higher total scores on the Multidimensional Perfectionism Scale than did the healthy comparison subjects. In addition, scores of the anorexia subjects on the Eating Disorder Inventory-2 perfectionism subscale exceeded Eating Disorder Inventory-2 normative data. For the anorexia nervosa participants, the total score on the Multidimensional Perfectionism Scale and the Eating Disorder Inventory-2 perfectionism subscale score were highly correlated. Total score on the Multidimensional Perfectionism Scale was also significantly related to the total score and the motivation-for-change subscale score of the Yale-Brown-Cornell Eating Disorder Scale. These data show that perfectionism is a robust, discriminating characteristic of anorexia nervosa. Perfectionism is likely to be one of a cluster of phenotypic trait variables associated with a genetic diathesis for anorexia nervosa.

  1. Social Science Energy Review: a quarterly publication. Vol. 1, No. 1

    Energy Technology Data Exchange (ETDEWEB)

    Gould, L C [ed.

    1978-01-01

    The Yale University Institution for Social and Policy Studies Mapping Project on Energy and the Social Sciences brings together an interdisciplinary group of Yale and visiting faculty, ISPS staff, and Yale graduate students meeting weekly to discuss topics in energy and the social sciences and to study and evaluate the importance for social policy of existing and potential social science energy research projects. The primary purposes of the project are: (1) to encourage timely social science investigations into important energy-related social issues, (2) to explore the present and potential roles for academic social science research in energy decision-making, and (3) to advise DOE and other government personnel in the planning of social science energy research. In addition to an overview of the Mapping Project, this report contains the following: (1) Social Science Research on ''The Energy Boomtown,'' by Leroy C. Gould--contains literature survey (66 references) and conveys Mapping Project's suggestions as to priorities on future social science research on ''energy boomtowns.'' (2) Men and Coal in Appalachia: a Survey of the Academic Literature, by Peter B. Allison (bibliography cites 7 journals, 3 government documents, and 70 books and articles). (3) Energy Research in Psychology, by John Sweeney (reprint of review of current status of energy research in psychology that appeared in December, 1977 issue of APA Monitor under the title, ''Boosting Energy Research'').

  2. Fandom unbound: Otaku culture in a connected world, edited by Mizuko Ito, Daisuke Okabe, and Izumi Tsuji [book review

    Directory of Open Access Journals (Sweden)

    Nele Noppe

    2015-03-01

    Full Text Available Review of Mizuko Ito, Daisuke Okabe and Izumi Tsuji, eds. Fandom unbound: Otaku culture in a connected world. New Haven, CT: Yale University Press, 2012, Kindle edition, $35; paperback, $38 (352p ISBN 978-0300158649.

  3. Early- and Late-Onset Inherited Erythromelalgia

    Directory of Open Access Journals (Sweden)

    J Gordon Millichap

    2009-08-01

    Full Text Available A genotype-phenotype relationship at the clinical, cellular and molecular levels is shown in a case of erythromelalgia of relatively late onset, in a study at Yale University School of Medicine, and centers in China.

  4. There's life in the old e-book yet

    CERN Multimedia

    Bryan, M

    2003-01-01

    "eBooks Corp has joined forces with Yale University and North Carolina State University in the US, Curtin University of Technology in Western Australia and nuclear research organisation CERN in Geneva to take textbooks online" (1/2 page).

  5. Health care politics and policy: the business of medicine: a course for physician leaders.

    Science.gov (United States)

    Marmor, Theodore Richard

    2013-09-01

    This article is a condensed and edited version of a speech delivered to the business of medicine: A Course for Physician Leaders symposium presented by Yale-New Haven Hospital and the Medical Directors Leadership Council at Yale University in November 2012 and drawn from Politics, Health, and Health Care: Selected Essays by Theodore R. Marmor and Rudolf Klein [1]. It faithfully reflects the major argument delivered, but it does not include the typical range of citations in a journal article. The material presented here reflects more than 40 years of teaching a course variously described as Political Analysis and Management, Policy and Political Analysis, and The Politics of Policy. The aim of all of these efforts is to inform audiences about the necessity of understanding political conflict in any arena, not least of which is the complex and costly world of medical care.

  6. A graduated food addiction classification approach significantly differentiates obesity among people with type 2 diabetes.

    Science.gov (United States)

    Raymond, Karren-Lee; Kannis-Dymand, Lee; Lovell, Geoff P

    2016-10-01

    This study examined a graduated severity level approach to food addiction classification against associations with World Health Organization obesity classifications (body mass index, kg/m 2 ) among 408 people with type 2 diabetes. A survey including the Yale Food Addiction Scale and several demographic questions demonstrated four distinct Yale Food Addiction Scale symptom severity groups (in line with Diagnostic and Statistical Manual of Mental Disorders (5th ed.) severity indicators): non-food addiction, mild food addiction, moderate food addiction and severe food addiction. Analysis of variance with post hoc tests demonstrated each severity classification group was significantly different in body mass index, with each grouping being associated with increased World Health Organization obesity classifications. These findings have implications for diagnosing food addiction and implementing treatment and prevention methodologies of obesity among people with type 2 diabetes.

  7. Entrevista a Leonardo Filippini: “Sáquenme de Estocolmo si me enamoro de mi secuestrador”

    Directory of Open Access Journals (Sweden)

    Silvana Lauzán

    2011-11-01

    Full Text Available Leonardo Filippini es abogado de la Universidad de Buenos Aires. Es máster en Derecho de la Universidad de Palermo y de la Universidad de Yale. Actualmente es Profesor de grado y posgrado en la Facultad de Derecho de la Universidad de Palermo, Investigador del Centro Internacional para la Justicia Transicional (ICTJ y candidato a doctor por la Escuela de Derecho de Yale. En esta entrevista, se discute sobre la Ley Nº 26.549 que modificó el Código Procesal Penal en Argentina, y que autoriza a la realización de pruebas compulsivas de ADN, en el contexto de los juicios que buscan restablecer la identidad de los niños y niñas apropiados o sustraídos ilegalmente durante la dictadur, y cuya identidad aún no se ha logrado establecer.

  8. Prof. Waghmare, Umesh V. (Secretary)

    Indian Academy of Sciences (India)

    Home; Fellowship. Fellow Profile. Elected: 2008 Section: Physics. Waghmare, Dr Umesh Vasudeo Ph.D. (Yale), FNASc, FNA Council Service: 2016-. Date of birth: 19 September 1968. Specialization: Multi-functional Oxides & Related Smart Materials, Nanostructures & Materials for Energy & Environment, Geometrics Phase ...

  9. Josiah Willard Gibbs

    Indian Academy of Sciences (India)

    The younger Gibbs grew up in the liberal and academic atmos- phere at Yale, where .... research in the premier European universities at the time when a similar culture ... tion in obscure journals, Gibbs' work did not receive wide recognition in ...

  10. Acoustic Neuroma Educational Video

    Medline Plus

    Full Text Available ... Provider List Member Portal Back Webinar Library Newsletter Library Patient Info Booklets Research Back ANA Survey/Registry AN Research Back Keck Medicine of USC Massachusetts General Hospital University of California, Irvine A.N.S.R.S. Study Yale ...

  11. PREFACE: Selected papers from the Fourth Annual q-bio Conference on Cellular Information Processing Selected papers from the Fourth Annual q-bio Conference on Cellular Information Processing

    Science.gov (United States)

    Nemenman, Ilya; Faeder, James R.; Hlavacek, William S.; Jiang, Yi; Wall, Michael E.; Zilman, Anton

    2011-10-01

    an evaluation of simulation methods for rule-based models. Delmotte et al follow with new methods for analysis of protein interaction dynamics. Finally, Schmidt et al present a novel method for automated experimental design for inference of metabolic networks. Acknowledgments We thank the authors who contributed to this special issue and the over 25 anonymous reviewers of manuscripts, as well as the staff of Physical Biology for their continued support of the q-bio conference. Additionally, we would like to thank the staff of St John's College Conference Services and the staff of the Center for Nonlinear Studies and the Theoretical Biology and Biophysics Group in Los Alamos, especially Adam Shipman, Don Thompson and Ellie Vigil. We also thank the Center for Nonlinear Studies and the Institute for Advanced Studies at Los Alamos National Laboratory, the NIGMS-funded Center for the Spatiotemporal Modeling of Cell Signaling at the University of New Mexico, the New Mexico Consortium, and NIGMS (NIH grant GM082162) for generous financial support. Finally, we thank the advisory and program committee members, who helped the organizers to assemble the program, recruit speakers, review submitted abstracts and publicize the event: Blagoy Blagoev (University of Southern Denmark), Naama Brenner (Technion), Thierry Emonet (Yale University), Alexander Hoffmann (University of California, San Diego), Diane S Lidke (University of New Mexico School of Medicine), Orna Resnekov (Molecular Sciences Institute), Thomas S Shimizu (FOM Institute for Atomic and Molecular Physics), Jin Zhang (Johns Hopkins University), Robert H Austin (Princeton University), Barbara A Baird (Cornell University), Elaine L Bearer (University of New Mexico School of Medicine), Michael E Berens (Translational Genomics Research Institute), Howard C Berg (Harvard University), Hans Frauenfelder (Los Alamos National Laboratory), Byron Goldstein (Los Alamos National Laboratory), Arthur D Lander (University of California

  12. Deconstruction and re-thinking education

    African Journals Online (AJOL)

    Erna Kinsey

    and the challenges it confronts in today's societies. In what follows, ... via the Yale School so that by the 1980s, English Departments in US higher education in- ..... student teachers; and teachers struggle to treat students fairly or to be agents of ...

  13. The role of psychosocial variables in physician judgement of pain ...

    African Journals Online (AJOL)

    ... and Method: 228 chronic pain patients completed the West Haven-Yale Multidimensional Pain Inventory (WHYMPI), while 69 completed both this instrument and the Addiction Potential, Anxiety, Health Concerns and Depression supplementary subscales of the Minnesota Multiphasic Personality Inventory – 2 (MMPI-2).

  14. Stress Controlled Catalysis via Engineered Nanostructures

    Science.gov (United States)

    2016-03-02

    Copenhagen Nicholas Dee Massachusetts Institute of Technology Francsico Schunk Brown University Ronald Dunn Brown University Bo Shen Brown University...Institute of Technology Zheng Jie Tan Massachusetts Institute of Technology Daniel Janda Brown University Andre D. Taylor Yale University Rongzhong Jiang U.S

  15. A map of taste neuron projections in the Drosophila CNS

    Indian Academy of Sciences (India)

    Department of Biological Sciences, Sungkyunkwan University, Suwon 440-746 Republic of Korea; Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, CT 06520-8103, USA; These authors contributed equally to the work. Department of Entomology, University of California, Riverside, ...

  16. Taus and the Trigger for Discovery at ATLAS

    International Nuclear Information System (INIS)

    Demers, Sarah

    2017-01-01

    This five year grant allowed Yale Professor Sarah Demers and her students and postdocs to contribute to the ATLAS Experiment at CERN's Large Hadron Collider. We worked on a particular mode of the Higgs Boson decay, contributing to the discovery of this particle as well as measuring the particle's properties. We also performed a 'first of its kind' measurement at a hadron collider in the measurement of tau polarization, which increased the sensitivity of ATLAS in a number of exciting ways, both for making measurements of known particles and for hunting for new ones. We also contributed to the tau trigger - the real-time selection that chooses data that includes the signature of the tau lepton. Four PhD students in the Yale Physics Department received their PhDs during the term of this grant, with at least partial support from the grant.

  17. The Southern Proper Motion Program. IV. The SPM4 Catalog

    Science.gov (United States)

    Girard, Terrence M.; van Altena, William F.; Zacharias, Norbert; Vieira, Katherine; Casetti-Dinescu, Dana I.; Castillo, Danilo; Herrera, David; Lee, Young Sun; Beers, Timothy C.; Monet, David G.; López, Carlos E.

    2011-07-01

    We present the fourth installment of the Yale/San Juan Southern Proper Motion Catalog, SPM4. The SPM4 contains absolute proper motions, celestial coordinates, and B, V photometry for over 103 million stars and galaxies between the south celestial pole and -20° declination. The catalog is roughly complete to V = 17.5 and is based on photographic and CCD observations taken with the Yale Southern Observatory's double astrograph at Cesco Observatory in El Leoncito, Argentina. The proper-motion precision, for well-measured stars, is estimated to be 2-3 mas yr-1, depending on the type of second-epoch material. At the bright end, proper motions are on the International Celestial Reference System by way of Hipparcos Catalog stars, while the faint end is anchored to the inertial system using external galaxies. Systematic uncertainties in the absolute proper motions are on the order of 1 mas yr-1.

  18. Manifold Adaptive Label Propagation for Face Clustering.

    Science.gov (United States)

    Pei, Xiaobing; Lyu, Zehua; Chen, Changqing; Chen, Chuanbo

    2015-08-01

    In this paper, a novel label propagation (LP) method is presented, called the manifold adaptive label propagation (MALP) method, which is to extend original LP by integrating sparse representation constraint into regularization framework of LP method. Similar to most LP, first of all, MALP also finds graph edges from given data and gives weights to the graph edges. Our goal is to find graph weights matrix adaptively. The key advantage of our approach is that MALP simultaneously finds graph weights matrix and predicts the label of unlabeled data. This paper also derives efficient algorithm to solve the proposed problem. Extensions of our MALP in kernel space and robust version are presented. The proposed method has been applied to the problem of semi-supervised face clustering using the well-known ORL, Yale, extended YaleB, and PIE datasets. Our experimental evaluations show the effectiveness of our method.

  19. Book Reviews

    Directory of Open Access Journals (Sweden)

    K.G. Tregonning

    1969-10-01

    Full Text Available - J. Th. Ros-Schrijvers, G.C. Mandersloot, Pakistan. Serie Land-Volk-Cultuur, Het Wereldvenster, Baarn 1968, 219 p., fotomateriaal. - J. Th. Ros-Schrijvers, Cora Vreede-De Stuers, Parda, a study of Muslim women’s life in Northern India. Van Gorcum & Comp. n.v., Assen 1968, 128 pp., fotomateriaal. - Obayashi Taryo, C. Ouwehand, Namazu-e and their themes. An interpretative approach to some aspects of Japanese folk religion. XVI, 271 pp., 10 text figures, 21 plates, 2 maps. E.J. Brill, Leiden 1964. - C. Ouwehand, Chie Nakane, Kinship and economic organization in rural Japan. London School of Economics Monographs on social anthropology No. 32. London 1967, 203 + IX pp. - O.D. van den Muijzenberg, Grant K. Goodman, Four aspects of Philippine-Japanese Relations, 1930-1940. Monograph Series no. 9, Southeast Asia Studies, Yale University, 1967. X + 237 pp. - J.M. Pluvier, John Bastin, A history of modern Southeast Asia; Colonialism, nationalism, and decolonization. Englewood Cliffs (N.J., Prentice-Hall, Inc., 1968, viii + 214 blz., bibliografie, index., Harry J. Benda (eds. - K.G. Tregonning, Journal of Southeast Asian History. Vol. x, No. 1, March 1969. “Singapore Commemorative Issue, 1819-1969. 150th Anniversary.” 191 p. - J.C. Anceaux, Rufus S. Hendon, The phonology and morphology of Ulu Muar Malay (Kuala Pilah District, Negri Sembilan, Malaya. Department of Anthropology, Yale University, New Haven 1966. (Yale University Publications in Anthropology, 70. 176 p. - Stephan A. Gasser, D. Drost, Töpferei in Afrika. Akademie-Verlag, Berlin, 1967. 289 S., 58 fig., 18 Karten, English summary.

  20. Evaluating the Impact of Conflict Resolution on Urban Children's Violence-Related Attitudes and Behaviors in New Haven, Connecticut, through a Community-Academic Partnership

    Science.gov (United States)

    Shuval, Kerem; Pillsbury, Charles A.; Cavanaugh, Brenda; McGruder, La'rie; McKinney, Christy M.; Massey, Zohar; Groce, Nora E.

    2010-01-01

    Numerous schools are implementing youth violence prevention interventions aimed at enhancing conflict resolution skills without evaluating their effectiveness. Consequently, we formed a community-academic partnership between a New Haven community-based organization and Yale's School of Public Health and Prevention Research Center to examine the…

  1. 76 FR 56820 - Detroit Edison Company, Fermi 2; Environmental Assessment and Finding of No Significant Impact

    Science.gov (United States)

    2011-09-14

    .... Ken Yale, of the Michigan Department of Natural Resources and Environment regarding the environmental...; Environmental Assessment and Finding of No Significant Impact The U.S. Nuclear Regulatory Commission (NRC) is..., the NRC performed an environmental assessment. Based on the results of the environmental assessment...

  2. Recommendations for Probiotic Use--2015 Update: Proceedings and Consensus Opinion

    NARCIS (Netherlands)

    Floch, Martin H.; Walker, W. Allan; Sanders, Mary Ellen; Nieuwdorp, Max; Kim, Adam S.; Brenner, David A.; Qamar, Amir A.; Miloh, Tamir A.; Guarino, Alfredo; Guslandi, Mario; Dieleman, Levinus A.; Ringel, Yehuda; Quigley, Eamonn M. M.; Brandt, Lawrence J.

    2015-01-01

    This paper describes the consensus opinion of the participants in the 4th Triennial Yale/Harvard Workshop on Probiotic Recommendations. The recommendations update those of the first 3 meetings that were published in 2006, 2008, and 2011. Recommendations for the use of probiotics in necrotizing

  3. The Uses of Speech in the Teaching of Literature: A Conversation with Maynard Mack.

    Science.gov (United States)

    Forrest, William Craig; Novelli, Cornelius

    1980-01-01

    Maynard Mack, Emeritus Sterling Professor of English at Yale, discusses his pioneering work with the oral interpretation of literature in the graduate and undergraduate English classroom, making the point that such oral techniques need not be limited to the drama or speech departments. (Author/SJL)

  4. The Reasons Requirement in International Investment Arbitration: Critical Case Studies (book review)

    DEFF Research Database (Denmark)

    Tang, Yi Shin

    2008-01-01

    3. In the article, the Researcher reviews the work of Professors Guillermo A. Alvarez and W. Michael Reisman from Yale Law School, regarding the mechanisms of international investment arbitration and their importance for developing countries. The article provides a critical perspective on the aut...

  5. Coping responses as predictors of psychosocial functioning ...

    African Journals Online (AJOL)

    ... West Haven-Yale Multidimensional Pain Inventory and the Coping Responses Inventory – Adult Form. The prevalence of the use of Avoidance and Approach Coping, and the relationship between these responses and psychosocial functioning (Pain Severity, Interference, Support, Life Control, and Affective Distress) were ...

  6. Second Chance or No Chance? A Case Study of One Urban Alternative Middle School

    Science.gov (United States)

    Kennedy-Lewis, Brianna L.

    2015-01-01

    This qualitative case study focuses on a school created to educate expelled students, specifically examining the relationships between educators' beliefs and philosophies and daily school life. At this school, Kelly's ("Last chance high." Yale University Press, New Haven, 1993) competing philosophies of "traditionalism" and…

  7. Democratic Values and Support for Militant Politics: Evidence from a National Survey of Pakistan

    Science.gov (United States)

    2012-11-27

    Swami, Praveen . 2007. India, Pakistan and the Secret Jihad: The Covert War in Kashmir 1947–2004. London: Routledge. Terror Free Tomorrow and the...Collapse in the International System, Second Edition. New Haven: Yale University Press. 12   Swami, Praveen . 2007. India, Pakistan and the

  8. Trends in Invasive Infection with MRSA

    Centers for Disease Control (CDC) Podcasts

    2012-07-17

    Dr. James Hadler, Associate Professor of Epidemiology and Public Health at the Yale School of Public Health, discusses recent trends in MRSA.  Created: 7/17/2012 by National Center for Emerging and Zoonotic Infectious Diseases (NCEZID).   Date Released: 7/19/2012.

  9. Genetics Home Reference: Gitelman syndrome

    Science.gov (United States)

    ... MJ, Lifton RP, Simon DB; Yale Gitelman's and Bartter's Syndrome Collaborative Study Group. Gitelman's syndrome revisited: an evaluation ... chloride channel gene, CLCNKB, leading to a mixed Bartter-Gitelman phenotype. Pediatr Res. 2000 ... NV, Levtchenko EN. Gitelman syndrome. Orphanet J Rare Dis. 2008 Jul 30;3: ...

  10. Risk of Status Epilepticus in Epilepsy

    Directory of Open Access Journals (Sweden)

    J Gordon Millichap

    2004-10-01

    Full Text Available The occurrence of status epilepticus (SE after the initial diagnosis of epilepsy was determined in a prospective community-based cohort study of 613 children at Montefiore Medical Center, Bronx, NY; Yale Medical School, New Haven, CT; and BIOS/NIU, DeKalb, IL.

  11. Staff members with 25 years' service at CERN in 2006

    CERN Multimedia

    2006-01-01

    The 34 staff members who have spent 25 years within CERN in 2006 were invited by the Director-General to a reception in their honour on 1st November. BELLEMAN Jeroen / AB BERTOLA Dominique / DSU BOLDI Armand / TS BOLLET André / AT BRANDT Daniel / DSU CACCIOPPOLI Michel /TS CALDERONE Antonino / TS CLARET René /TS COSSEY PUGET Françoise / PH DALEXANDRO Noël / AT DECOMBAZ Michel / TS DELLA NEGRA Michel / PH DINIUS Arend / AB FOSTER David / IT FROMM Christine / DSU GROS Daniel / TS GUDET Denis / TS LEWIS Julian / AB MAPELLI Livio / PH MASSON Albert / TS MOINE Catherine / PH MÜLLER Hans / PH ODIER Patrick / AB PANMAN Jaap / PH POOLE John / AB PROLA-TESSAUR Maureen / AT RAPHOZ Jean-Pierre / IT ROSTANT Jeanne / PH RUGO Erminio / AB VAN HERWIJNEN Eric / PH WERNER Per / PH WILDNER Elena / AT WILKINSON Jonathan / DSU WISZNIOWSKI Thierry / AB

  12. Elections to the Senior Staff Advisory Committee (“The Nine”) 2013

    CERN Multimedia

    Jean-Philippe Tock, spokesperson of the "Nine"

    2013-01-01

    The electronic voting process for the Senior Staff Advisory Committee (“The Nine”) was closed on Thursday, 29 August 2013 at 18.00. Of the 503 Senior Staff members eligible to vote, 316 voted. This represents a participation of 63%, compared to 61% in 2012, 43% in 2011, 44% in 2010, 57% in 2009, 53% in 2008, 63% in 2007, 64% in 2006 and 66% in 2005. The results are: Electoral group 1 (Research Physicists) Candidate Dept Votes Result Augusto CECCUCCI PH 157 ELECTED   Electoral group 2 (Applied Physicists, Engineers, Computer Scientists) Candidate Dept Votes Result Ronny BILLEN BE 32   Johan BREMER TE 35   Katy FORAZ EN 51   Malika MEDDAHI TE 72 ELECTED Pierre NININ GS 10   Thomas OTTO TE 15   Sandro PALESTINI PH 17   Christoph REMBSER PH 54   Thierry STO...

  13. COMPOSITION OF STAFF REVIEW ADVISORY BODIES - 2001

    CERN Multimedia

    Seamus Hegarty / HR; Tel. 74128

    2001-01-01

    For the present staff review, the advisory bodies set up to prepare recommendations are composed as follows : Senior Staff Advancement Committee (SSAC) David O. Williams/it (Convener) Cristoforo Benvenuti/est David Plane/ep Technical Engineers & Administrative Careers Committee (TEACC) Sverre Jarp/it (Chairman) Flemming Pedersen/ps Robin Lauckner/sl Christian Roche/ett Lars Leistam/est Dietrich Schinzel/ep Long-term contract Boards (LTCBs) LTCB 1 (Categories 2 & 5a) Tiziano Camporesi/ep [Convener] - Florence Ranjard/ep [Alternate] Jacques Gruber/ps - Peter Sievers/lhc [Alternate] Thomas Pettersson/est - Michel Mayoud/est [Alternate] Sue Foffano/as - Thierry Lagrange/spl [Alternate] Werner Zapf/hr (Secretary) LTCB 2 (Categories 3, 4, 5b & 5c) Véronique Paris/sl [Convener] - Fabien Perriollat/ps [Alternate] Mats Wilhelmsson/st - Véronique Fassnacht/tis [Alternate] Lucie Linssen/ep - Alfredo Placci/ep [Alternate] Patrick Geeraert/fi - John Cuthb...

  14. 2014 Accelerators meeting, Grenoble

    International Nuclear Information System (INIS)

    Lucotte, Arnaud; Lamy, Thierry; De Conto, Jean-Marie; Fontaine, Alain; Revol, Jean-Luc; Nadolski, Laurent S.; Kazamias, Sophie; Vretenar, Maurizio; Ferrando, Philippe; Laune, Bernard; Vedrine, Pierre

    2014-10-01

    The Accelerators meeting is organised every two years by the Accelerators division of the French Society of Physics (SFP). It brings together about 50 participants during a one-day meeting. The morning sessions are devoted to scientific presentations while the afternoon is dedicated to technical visits of facilities. This document brings together the available presentations (slides): 1 - Presentation of the Laboratory of subatomic physics and cosmology - LPSC-Grenoble (Lucotte, Arnaud; Lamy, Thierry); 2 - Presentation of the Accelerators division of the French Society of Physics (Fontaine, Alain; Revol, Jean-Luc); 3 - Presentation of Grenoble's master diplomas in Accelerator physics (Nadolski, Laurent S.); 4 - Presentation of Paris' master diplomas in big instruments (Kazamias, Sophie); 5 - Particle accelerators and European Union's projects (Vretenar, Maurizio); 6 - French research infrastructures (Ferrando, Philippe); 7 - Coordination of accelerators activity in France (Laune, Bernard; Vedrine, Pierre)

  15. USSR Report, USA: Economics, Politics, Ideology, No. 11, November 1983

    Science.gov (United States)

    1984-01-31

    McCarthy and other dinosaurs of anticommunism. Nor has American policy progressed since those days. I do not know why Americans have such a short...studying metabolical reactions directly in organs and tissues (the article by Yale University Professor R. Shulman, "The NMR-Aided Examination of

  16. Conversion Narratives and Construction of Identity among Christians in Malaysia

    Science.gov (United States)

    Dumanig, Francisco Perlas; David, Maya Khemlani; Dealwis, Ceasar

    2011-01-01

    Conversion narratives in the form of testimony are powerful means of consolidating and strengthening one's new religious identity (Beit-Hallahmi, Prolegomena to the psychological study of religion, Bucknell University Press, 1989; Rambo, Understanding religious conversion, Yale University Press, 1993; Stromberg 1993, as cited in Emmons &…

  17. sequential low cost interventions double hand hygiene rates among

    African Journals Online (AJOL)

    2014-02-02

    Feb 2, 2014 ... Request for reprints to: Onyema Ogbuagu, Yale University School of Medicine, Address – 135 College Street, suite 323, ... Objective: To assess the impact of multimodal low-cost interventions on hand hygiene ... system change including investment in provision ... Statistical software used was IBM SPSS.

  18. Novel Structure and Function of Typhoid Toxin

    Science.gov (United States)

    ... become infected with the bacteria by consuming contaminated food or beverages. Once inside the body, the bacteria multiply and ... other types of Salmonella bacteria cause salmonellosis or food poisoning, S. ... and Jorge Galán of Yale University set out to determine the reason for the ...

  19. THE SENSITIVITY TO CHANGE OF MEASURES FOR OBSESSIVE-COMPULSIVE DISORDER

    NARCIS (Netherlands)

    VANOPPEN, P; EMMELKAMP, PMG; VANBALKOM, AJLM; VANDYCK, R

    1995-01-01

    This study presents data on the sensitivity to change of the Padua Inventory-Revised (PI-R), the Yale Brown Obsessive Compulsive Scale (Y-BOCS), and the Anxiety Discomfort Scale (ADS) for obsessive-compulsive disorder. In a sample of obsessive-compulsives (n = 63) who received either behaviour

  20. Journal of Biosciences | Indian Academy of Sciences

    Indian Academy of Sciences (India)

    Anandasankar Ray1 2 Wynand Van Der Goes Van Naters2 3 John R Carlson2. Department of Entomology, University of California, Riverside, CA 92521, USA; Department of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, CT 06520, USA; School of Biosciences, Cardiff University, Cardiff, UK ...

  1. Lectures on Chevalley groups

    CERN Document Server

    Steinberg, Robert

    2016-01-01

    Robert Steinberg's Lectures on Chevalley Groups were delivered and written during the author's sabbatical visit to Yale University in the 1967-1968 academic year. The work presents the status of the theory of Chevalley groups as it was in the mid-1960s. Much of this material was instrumental in many areas of mathematics, in particular in the theory of algebraic groups and in the subsequent classification of finite groups. This posthumous edition incorporates additions and corrections prepared by the author during his retirement, including a new introductory chapter. A bibliography and editorial notes have also been added. This is a great unsurpassed introduction to the subject of Chevalley groups that influenced generations of mathematicians. I would recommend it to anybody whose interests include group theory. -Efim Zelmanov, University of California, San Diego Robert Steinberg's lectures on Chevalley groups were given at Yale University in 1967. The notes for the lectures contain a wonderful exposition of ...

  2. OBSERVATIONS OF BINARY STARS WITH THE DIFFERENTIAL SPECKLE SURVEY INSTRUMENT. I. INSTRUMENT DESCRIPTION AND FIRST RESULTS

    International Nuclear Information System (INIS)

    Horch, Elliott P.; Veillette, Daniel R.; Shah, Sagar C.; O'Rielly, Grant V.; Baena Galle, Roberto; Van Altena, William F.

    2009-01-01

    First results of a new speckle imaging system, the Differential Speckle Survey Instrument, are reported. The instrument is designed to take speckle data in two filters simultaneously with two independent CCD imagers. This feature results in three advantages over other speckle cameras: (1) twice as many frames can be obtained in the same observation time which can increase the signal-to-noise ratio for astrometric measurements, (2) component colors can be derived from a single observation, and (3) the two colors give substantial leverage over atmospheric dispersion, allowing for subdiffraction-limited separations to be measured reliably. Fifty-four observations are reported from the first use of the instrument at the Wisconsin-Indiana-Yale-NOAO 3.5 m Telescope 9 The WIYN Observatory is a joint facility of the University of Wisconsin-Madison, Indiana University, Yale University, and the National Optical Astronomy Observatories. in 2008 September, including seven components resolved for the first time. These observations are used to judge the basic capabilities of the instrument.

  3. Electromagnetic Studies of Mesons, Nucleons, and Nuclei

    Energy Technology Data Exchange (ETDEWEB)

    Baker, Oliver K.

    2013-08-20

    Professor Baker was a faculty member at Hampton University in Hampton, Virginia, and, jointly, a Staff Physicist at Jefferson Lab in nearby Newport News from September 1989 to July 2006. The Department of Energy (DOE) funded the grant DE-FG02-97ER41035 Electromagnetic Studies of Mesons, Nucleons, and Nuclei, while Baker was in this joint appointment. Baker sent a closeout report on these activities to Hampton University’s Sponsored Research Office some years ago, shortly after joining Yale University in 2006. In the period around 2001, the research grant with Baker as the Principal Investigator (PI) was put under the supervision of Professor Liguang Tang at Hampton University. Baker continued to pursue the research while in this join appointment, however the administrative responsibilities with the DOE and with Hampton University rested with Professor Tang after 2001, to my recollection. What is written in this document is from Baker’s memory of the research activities, which he has not pursued since joining the Yale University faculty.

  4. Brand Management in US Business Schools: Can Yale Learn from Harvard?

    Science.gov (United States)

    Heyes, Anthony G.; Liston-Heyes, Catherine

    2004-01-01

    Data Envelopment Analysis (DEA) is used to evaluate the performance of top US business school in maintaining reputation among members of the academic and business communities. The authors generate efficiency measures and identify peers against which underperforming schools should benchmark.

  5. David J. Feldman | NREL

    Science.gov (United States)

    Analysis Center. Areas of Expertise Renewable energy project finance Corporate finance Solar energy market policy Corporate finance in energy sector Education M.B.A. from the Yale School of Management, New Haven Finance, Soltage, Jersey City, NJ (2007-2010) Associate, The Jordan Edmiston Group, New York, NY (2006

  6. Somatostatin and dopamine receptors as molecular targets for the medical treatment of Cushing’s disease

    NARCIS (Netherlands)

    C. de Bruin (Christiaan)

    2009-01-01

    textabstractHarvey Williams Cushing (1869-1939) was born as the 10th child of a well-educated, puritanical medical family in Cleveland (figure 1). He attended Yale University, graduated cum laude from Harvard Medical School and was trained as a general surgeon at Johns Hopkins under the famous

  7. 76 FR 56491 - Culturally Significant Objects Imported for Exhibition Determinations: “Adapting the Eye: An...

    Science.gov (United States)

    2011-09-13

    ...,'' imported from abroad for temporary exhibition within the United States, are of cultural significance. The... that the exhibition or display of the exhibit objects at the Yale Center for British Art, New Haven... Cultural Exchanges, Bureau of Educational and Cultural Affairs, Department of State. [FR Doc. 2011-23355...

  8. 75 FR 6079 - Culturally Significant Objects Imported for Exhibition

    Science.gov (United States)

    2010-02-05

    ... cultural significance. The objects are imported pursuant to loan agreements with the foreign owners or custodians. I also determine that the exhibition or display of the exhibit objects at the Yale Center for... Professional and Cultural Exchanges, Bureau of Educational and Cultural Affairs, Department of State. [FR Doc...

  9. Why don't ants play? An interview with Mark W. Moffett

    DEFF Research Database (Denmark)

    Prager, Phillip

    2014-01-01

    . Moffett has appeared on The Tonight Show with Conan O’Brien and The Colbert Report and has received the Lowell Thomas Award from the Explorers Club, the Distinguished Explorer Award from the Roy Chapman Andrews Society, Yale University’s Poynter Fellowship in Journalism, and Harvard’s Bowdoin Prize...

  10. 76 FR 55956 - Self-Regulatory Organizations; NYSE Arca, Inc.; Notice of Filing of Proposed Rule Change To List...

    Science.gov (United States)

    2011-09-09

    ... Commentary .02(b)(4) to NYSE Arca Equities Rule 8.200, means any combination of investments, including cash... investment objective of USMI is for the daily changes in percentage terms of its Units' net asset value... Fundamentals of Commodity Futures Returns,'' Gorton, Rouwenhorst and Hayashi (September 2008), Yale...

  11. Fulltext PDF

    Indian Academy of Sciences (India)

    IAS Admin

    Physiology or Medicine. “for their discoveries of machinery regulating vesicle traffic, a major transport system in our cells” to. James E Rothman, Yale University, New Haven, CT, USA,. Randy W Schekman, University of California, Berkeley, CA, USA; Howard Hughes Medical. Institute ,. Thomas C Südhof, Stanford University ...

  12. CIFOL: Case-intensional first order logic. (I) Toward a theory of sorts

    NARCIS (Netherlands)

    Belnap, Nuel; Müller, Thomas

    2012-01-01

    This is Part I of a two-part essay introducing case-intensional first-order logic (CIFOL), an easy-to-use, uniform, powerful, and useful combination of first order logic with modal logic resulting from philosophical and technical modifications of Bressan’s General interpreted modal calculus (Yale

  13. Ärimudelid Ameerika (ja Eesti) kvaliteetajalehtede päästmiseks / Mikk Salu

    Index Scriptorium Estoniae

    Salu, Mikk, 1975-

    2009-01-01

    CNN-i endine juht Walter Isaacson pakkus välja mikromaksete süsteemi, kus ajalehtede online-versiooni sisu hakatakse müüma artikli kaupa. Yale'i ülikooli finantsjuhi David Swenseni arvates võiksid kvaliteetajalehed kopeerida ülikoolides kasutatavat ärimudelit - mittetulundusühingutest tuleks muutuda investeerimisfondideks

  14. Alejo Carpentier: Lo real y lo maravilloso en "El Reino de Este Mundo" (Alejo Carpentier: The Real and the Fantastic in "The Rule of the World")

    Science.gov (United States)

    Rodriguez Monegal, Emir

    1971-01-01

    Special issue dedicated to studies on contemporary Spanish American literature. Paper read at the symposium on Alejo Carpentier organized by Klaus Muller-Bergh at Yale University, New Haven, Connecticut, under the auspices of the Antilles Research Program of the Council for Latin American Studies, on April 17, 1971. (DS)

  15. Clinical features of tic-related obsessive-compulsive disorder: results from a large multicenter study.

    Science.gov (United States)

    Gomes de Alvarenga, Pedro; de Mathis, Maria Alice; Dominguez Alves, Anna Claudia; do Rosário, Maria Conceição; Fossaluza, Victor; Hounie, Ana Gabriela; Miguel, Euripedes Constantino; Rodrigues Torres, Albina

    2012-06-01

    To evaluate the clinical features of obsessive-compulsive disorder (OCD) patients with comorbid tic disorders (TD) in a large, multicenter, clinical sample. A cross-sectional study was conducted that included 813 consecutive OCD outpatients from the Brazilian OCD Research Consortium and used several instruments of assessment, including the Yale-Brown Obsessive-Compulsive Scale, the Dimensional Yale-Brown Obsessive-Compulsive Scale, the Yale Global Tic Severity Scale (YGTSS), the USP Sensory Phenomena Scale, and the Structured Clinical Interview for DSM-IV Axis I Disorders. The sample mean current age was 34.9 years old (SE 0.54), and the mean age at obsessive-compulsive symptoms (OCS) onset was 12.8 years old (SE 0.27). Sensory phenomena were reported by 585 individuals (72% of the sample). The general lifetime prevalence of TD was 29.0% (n = 236), with 8.9% (n = 72) presenting Tourette syndrome, 17.3% (n = 141) chronic motor tic disorder, and 2.8% (n = 23) chronic vocal tic disorder. The mean tic severity score, according to the YGTSS, was 27.2 (SE 1.4) in the OCD + TD group. Compared to OCD patients without comorbid TD, those with TD (OCD + TD group, n = 236) were more likely to be males (49.2% vs. 38.5%, p disorders in general: separation anxiety disorder, social phobia, specific phobia, generalized anxiety disorder, post-traumatic stress disorder, attention-deficit hyperactivity disorder, impulse control disorders in general, and skin picking. Also, the "aggressive," "sexual/religious," and "hoarding" symptom dimensions were more severe in the OCD + TD group. Tic-related OCD may constitute a particular subgroup of the disorder with specific phenotypical characteristics, but its neurobiological underpinnings remain to be fully disentangled.

  16. Early onset obsessive-compulsive disorder with and without tics.

    Science.gov (United States)

    de Mathis, Maria Alice; Diniz, Juliana B; Shavitt, Roseli G; Torres, Albina R; Ferrão, Ygor A; Fossaluza, Victor; Pereira, Carlos; Miguel, Eurípedes; do Rosario, Maria Conceicão

    2009-07-01

    Research suggests that obsessive-compulsive disorder (OCD) is not a unitary entity, but rather a highly heterogeneous condition, with complex and variable clinical manifestations. The aims of this study were to compare clinical and demographic characteristics of OCD patients with early and late age of onset of obsessive-compulsive symptoms (OCS); and to compare the same features in early onset OCD with and without tics. The independent impact of age at onset and presence of tics on comorbidity patterns was investigated. Three hundred and thirty consecutive outpatients meeting Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition criteria for OCD were evaluated: 160 patients belonged to the "early onset" group (EOG): before 11 years of age, 75 patients had an "intermediate onset" (IOG), and 95 patients were from the "late onset" group (LOG): after 18 years of age. From the 160 EOG, 60 had comorbidity with tic disorders. The diagnostic instruments used were: the Yale-Brown Obsessive Compulsive Scale and the Dimensional Yale-Brown Obsessive Compulsive Scale (DY-BOCS), Yale Global Tics Severity Scale, and Structured Clinical Interview for DSM-IV Axis I Disorders-patient edition. Statistical tests used were: Mann-Whitney, full Bayesian significance test, and logistic regression. The EOG had a predominance of males, higher frequency of family history of OCS, higher mean scores on the "aggression/violence" and "miscellaneous" dimensions, and higher mean global DY-BOCS scores. Patients with EOG without tic disorders presented higher mean global DY-BOCS scores and higher mean scores in the "contamination/cleaning" dimension. The current results disentangle some of the clinical overlap between early onset OCD with and without tics.

  17. Full remission and relapse of obsessive-compulsive symptoms after cognitive-behavioral group therapy: a two-year follow-up Remissão completa e recaídas dos sintomas obsessivo-compulsivos depois da terapia cognitivo-comportamental em grupo: dois anos de acompanhamento

    Directory of Open Access Journals (Sweden)

    Daniela Tusi Braga

    2010-06-01

    Full Text Available OBJECTIVE: The aim of this study was to assess whether the results obtained with 12 sessions of cognitive-behavioral group therapy with obsessive-compulsive patients were maintained after two years, and whether the degree of symptom remission was associated with relapse. METHOD: Forty-two patients were followed. The severity of symptoms was measured at the end of cognitive-behavioral group therapy and at 18 and 24 months of follow-up. The assessment scales used were the Yale-Brown Obsessive-Compulsive Scale, Clinical Global Impression, Beck Depression Inventory, and Beck Anxiety Inventory. RESULTS: The reduction in symptom severity observed at the end of treatment was maintained during the two-year follow-up period (F = 57.881; p OBJETIVO: Avaliar se os resultados obtidos com 12 sessões de terapia cognitivo-comportamental em grupo para pacientes com transtorno obsessivo-compulsivo foram mantidos depois de dois anos do final do tratamento e se o grau de remissão dos sintomas esteve associado às recaídas. MÉTODO: Quarenta e dois pacientes foram acompanhados. A gravidade dos sintomas foi avaliada no final da terapia cognitivo-comportamental em grupo, 18 e 24 meses após o término do tratamento. As escalas utilizadas para avaliação foram Yale-Brown Obsessive-Compulsive Scale, Clinical Global Impression, Beck Depression Inventory e Beck Anxiety Inventory. RESULTADOS: A redução da gravidade dos sintomas observada no final do tratamento foi mantida durante o período de dois anos de acompanhamento (F = 57,881; p < 0,001. Ao final do tratamento, 9 (21,4% pacientes apresentaram remissão completa, 22 (52,4% remissão parcial e 11 (26,2% não apresentaram mudança na Yale-Brown Obsessive-Compulsive Scale. Dois anos depois, 13 pacientes (31,0% apresentaram remissão completa dos sintomas, 20 (47,6% apresentaram remissão parcial, e 9 (21,4% não apresentaram mudança na Yale-Brown Obsessive-Compulsive Scale. A remissão completa dos sintomas ao

  18. Wavelength scaling of the two-plasmon decay and stimulated Raman-scattering instabilities. Annual progress report, September 10, 1981-September 9, 1982

    International Nuclear Information System (INIS)

    Chen, F.F.; Joshi, C.; Ebrahim, N.A.

    1983-03-01

    This report contains description of the joint work done by the UCLA-Yale Users' Group at NLUF, LLE Rochester on the two plasmon decay and stimulated Raman scattering instabilities at 0.35 μm laser wavelength. A brief summary of the theoretical work on how SBS influences SRS is also given

  19. 78 FR 7849 - Culturally Significant Objects Imported for Exhibition

    Science.gov (United States)

    2013-02-04

    ... Century,'' imported from abroad for temporary exhibition within the United States, are of cultural... also determine that the exhibition or display of the exhibit objects at The Yale Center for British Art..., Bureau of Educational and Cultural Affairs, Department of State. [FR Doc. 2013-02401 Filed 2-1-13; 8:45...

  20. Training, Communication, and Competence: The Making of Health Care Professionals

    Science.gov (United States)

    Luong, My-Linh

    2009-01-01

    The role of medical anthropology in tackling the problems and challenges at the intersections of public health, medicine, and technology was addressed during the 2009 Society for Medical Anthropology Conference at Yale University in an interdisciplinary panel session entitled Training, Communication, and Competence: The Making of Health Care Professionals. PMID:20027287

  1. Facilities for Study and Research in the Offices of the United States Government at Washington. Bulletin, 1909, No. 1. Whole Number 398

    Science.gov (United States)

    Hadley, Arthur Twining

    1909-01-01

    This bulletin contains a report prepared by President Hadley of Yale University on the facilities for advanced study and research in the offices of the National Government at Washington. Especial interest attaches to this publication. It sets forth, in compact form, information which has frequently been sought by institutions and individuals…

  2. Political Bias on Campus: Understanding the Student Experience

    Science.gov (United States)

    Linvill, Darren L.; Havice, Pamela A.

    2011-01-01

    The role ideology plays in the university classroom has been debated since the publication of Buckley's "God and Man at Yale" (1951). The "Chronicle of Higher Education's" Special Report (2004) found that more than half of United States citizens polled felt that U.S. colleges and universities improperly introduce a liberal…

  3. Groundbreaking Investigator of Creativity: An Interview with James C. Kaufman

    Science.gov (United States)

    Henshon, Suzanna E.

    2010-01-01

    This article presents an interview with James C. Kaufman, an associate professor of psychology at the California State University at San Bernardino, where he directs the Learning Research Institute. Kaufman received his PhD in cognitive psychology from Yale University in 2001. Dr. Kaufman's research broadly focuses on nurturing and encouraging…

  4. Quod licet Iovi... / Toomas Hendrik Ilves

    Index Scriptorium Estoniae

    Ilves, Toomas Hendrik, 1953-

    2006-01-01

    Arvustus: Fukuyama, Francis. America at the Crossroads: Democracy, Power, and the Neoconservative Legacy. New Haven ; London : Yale University Press, 2006. Ameerika Ühendriikide neokonservatiivse välispoliitika analüüs, uuskonservatismi sünd ja selle vaimsed allikad; ennetava sõja kontseptsiooni mõju väikeste riikide julgeolekule

  5. Wotan’s Workshop: Military Experiments Before the Second World War

    Science.gov (United States)

    2002-10-01

    1980. Kuenne, Robert E. The Attack Submarine: A study in strategy. New Haven: Yale University Press, 1965. Lanchester, Frederick W. Aircraft in Warfare...little-known Francis Edward Smedley . [8] Typical applications of this phrase appear on pages 35 and 40 of the novel by DiMercurio. [9] Except as otherwise

  6. Colorful Event Lands Off Campus Customers.

    Science.gov (United States)

    Ballard, Richard E.

    1978-01-01

    To attract suburban, nonstudent customers, the Yale Cooperative Corporation held a Heirloom Discovery Day. Co-op books and materials were sold to customers who came with antique items to be appraised. Donations from the profits were made to the New Haven Symphony and the University Collection of Musical Instruments. (JMD)

  7. Retirement Plan Lawsuits: Preparing for the Storm

    Science.gov (United States)

    Morahan, John; Turner, Aaron

    2017-01-01

    Currently, higher education is being roiled by class-action lawsuits filed against high-profile institutions, including MIT, Yale and New York University, over management of their retirement plans. As the lawyers are deployed and the billable hours accrue, it is timely to examine how those who have responsibility for retirement plan…

  8. Die Mathematik und andere Kurzsprachen : Über John von Neumann, The Computer and the Brain

    NARCIS (Netherlands)

    Leydesdorff, L.; Baecker, D.

    2016-01-01

    Das Buch The Computer and the Brain (1958, dt. 1991; im Folgenden wird nach der deutschen Übersetzung zitiert) ist die gedruckte Version der Silliman Lectures, die zu halten John von Neumann 1956 nach Yale eingeladen worden war. Obwohl sie bis zum März 1956 vorbereitet waren, wurden sie nie

  9. Finanskrisen var forudset

    DEFF Research Database (Denmark)

    Grosen, Anders

    2008-01-01

    Kun de færreste har kunnet forudsige den aktuelle finanskrises omfang og overordnede karakteristika. Men som vi skal se i det følgende, har Yale-professoren Robert J. Shillers forudsigelse af krisen været forbavsende præcis. Det deprimerende er, at finanssystemets beslutningsdeltagere ikke tog ad...

  10. Is the N170 face specific? Controversy, context, and theory

    Directory of Open Access Journals (Sweden)

    Brian D. Earp

    2013-04-01

    Full Text Available In cognitive science, there is an ongoing debate about the architecture of the mind: does it consist of a number of mental “organs” each managing a different function in isolation, or is it more of general processor, adaptable to a wide range of tasks? One corner of this debate has centered on face processing. This is because face-perception is crucial to normal human functioning and some evidence shows that faces may be processed by the brain in a privileged way compared to other types of stimuli. For example, in EEG brain recordings, the N170 is a characteristic signal that occurs after a participant is exposed to an image of a face, but it is much less pronounced when other stimuli are shown. More than 15 years of research on the “N170 face effect” have yielded the standard view that the N170 is at the very least face-sensitive, and possibly even face-specific, that is, indexing modular processes tied exclusively to facial geometries. The specificity claim is clearly stronger, and hence subject to significant controversy; while the more conservative “sensitivity” claim had been regarded (until recently as effectively settled. Nevertheless, Thierry and colleagues, in a contentious 2007 article, sought to undermine even this “conservative” consensus: they argued that the apparent face-responsiveness of the N170 in prior research was due to systematic flaws in experimental design. Fiery debate has followed. In this review, we put the debate in its historical and philosophical context, and try to spell out some of the theoretical and logical assumptions that underlie the claims of the competing camps. We then show that the best available evidence counts, at least partially, against the Thierry et al. construal of the N170. Accordingly, it would be premature to abandon the “conservative” account of the N170, according to which it is – minimally – responsive to faces. We conclude by returning to the more controversial claim

  11. Transfusion management using a remote-controlled, automated blood storage.

    Science.gov (United States)

    Pagliaro, Pasqualepaolo; Turdo, Rosalia

    2008-04-01

    Generally, the safety of transfusion terapies for patients depends in part on the distribution of the blood products. The prevention of adverse events can be aided by technological means, which, besides improving the traceability of the process, make errors less likely. In this context, the latest frontier in automation and computerisation is the remote-controlled, automated refrigerator for blood storage. Computer cross-matching is an efficient and safe method for assigning blood components, based on Information Technology applied to typing and screening. This method can be extended to the management of an automated blood refrigerator, the programme of which is interfaced with the Transfusion Service's information system. The connection we made in our Service between EmoNet and Hemosafe enables real-time, remote-controlled management of the following aspects of blood component distribution: a) release of autologous and allogeneic units already allocated to a patient, b) release of available units, which can be allocated by remote-control to known patients, in the presence of a valid computer cross-match, c) release of O-negative units of blood for emergencies. Our system combines an information database, which enables computer cross-matching, with an automated refrigerator for blood storage with controlled access managed remotely by the Transfusion Service. The effectiveness and safety of the system were validated during the 4 months of its routine use in the Transfusion Service's outpatient department. The safety and efficiency of the distribution of blood products can and must be increased by the use of technological innovations. With the EmoNet/Hemosafe system, the responsibility for the remote-controlled distribution of red blood cell concentrates remains with the chief of the Transfusion Services, through the use of automated computer procedures and supported by continuous training of technicians and nursing staff.

  12. Scientific Information Policy Board 90th Meeting

    CERN Multimedia

    AUTHOR|(CDS)2051371

    2017-01-01

    Gigi Rolandi, sitting in the middle, chairing his last meeting of the Scientific Information Policy Board before his retirement. Rolandi was the chairman of the board from March 2006 until April 2017, a period that has seen lots of dynamics within the field of authoring, publishing and librarianship - both at CERN and beyond. In the first row from left to right: Eckhard Elsen (Director of Research), Jens Vigen (Head Librarian) Gigi Rolandi (SIPB Chair), Anita Hollier (Archivist) and Urs Wiedemann (Theory). In the second row from left to right: Nikos Kasioumis (Invited speaker), Alexander Kohls (Invited speaker), Stella Christodoulaki (Invited speaker), Nick Ellis (Chair CREB), Clara Troncon (ACCU), Annette Holtkamp (Scientific Information Service), Tim Smith (IT) Brigitte Bloch-Devaux (non-LHC experiments), Constantinos Loizides (ALICE), Thierry Stora (Engineering), John Jowett (Beams), Arjan Verweij (Technology), Anne Gentil-Beccot (Scientific Information Service), Fergus Wilson (LHCb), Ludmila Marian (Invit...

  13. Neurolinguistics Aspects of Second Language Acquisition

    Directory of Open Access Journals (Sweden)

    Laleh Fakhraee Faruji

    2011-12-01

    Full Text Available   Fundamental breakthroughs in the neurosciences, combined with technical innovations for measuring brain activity, are shedding new light on the neural basis of second language (L2
    processing, and on its relationship to native language processing (L1 (Perani & Abutalebi, 2005.  Over the past two decades, a large body of neuroimaging studies has been devoted to the study of the neural organization of language (De´monet, Thierry, & Cardebat, 2005; Indefrey & Levelt, 2004; Price, 2000 as cited in Abutalebi, 2008. The value that functional neuroimaging adds to language research is to improve the perspective on the distributed anatomy of language. Thus, it can be used with considerable precision to identify the neural networks underlying the different domains of language processing. In this paper some main issues related to neurolinguistics and second language acquisition with a focus on bilingualism will be discussed.

  14. Motivating Non-Science Majors: The Technology of Electromagnetic Waves

    Science.gov (United States)

    Henrich, Victor E.

    2018-01-01

    To address the need for physics courses that stimulate non- STEM majors' interest in, and appreciation of, science, the Department of Applied Physics has developed a popular course for Yale College undergraduates, The Technological World, that explains the physics behind technologies that students use every day. The course provides an in-depth…

  15. Elite Destinations: Pathways to Attending an Ivy League University

    Science.gov (United States)

    Mullen, Ann L.

    2009-01-01

    As higher education expands and becomes more differentiated, patterns of class stratification remain deeply entrenched, in part due to class-based differences in college choice. A qualitative study of 50 Yale students shows the effects of social class, high schools and peers on students' pathways to college. For students from wealthy and highly…

  16. The Essence of Good Teaching.

    Science.gov (United States)

    Sherman, Robert R.

    1986-01-01

    Compares and contrasts views of what constitutes good teaching in four recent books: "My Harvard, My Yale: Memoirs of College Life by Some Notable Americans" (Dubois, 1982); "Twenty Teachers" (Macrorie, 1984); "Artistry in Teaching" (Rubin, 1985); and "The Essence of Good Teaching: Helping Students Learn and Remember What They Learn" (Eriksen,…

  17. Unlocking the Gates: How and Why Leading Universities Are Opening up Access to Their Courses

    Science.gov (United States)

    Walsh, Taylor

    2011-01-01

    Over the past decade, a small revolution has taken place at some of the world's leading universities, as they have started to provide free access to undergraduate course materials--including syllabi, assignments, and lectures--to anyone with an Internet connection. Yale offers high-quality audio and video recordings of a careful selection of…

  18. A Study to Develop a Model for the Allocation of Medical Supply Funds to the Various Clinical Services at Keller Army Community Hospital Based Upon Inpatient Weighted Units and Ambulatory Weighted Units

    Science.gov (United States)

    1989-05-11

    zDiagnosis Related Groups (DRGs), as developed by ther Mz researchers at Yale University in the late 1960s, were a m mmeans of classifying patients by...the group’s recalibration of the Rickard 19 ambulatory portion of the HCU was most important. This was because it resulted in, "an ambulatory

  19. A Spacefaring People: Perspectives on Early Spaceflight.

    Science.gov (United States)

    Roland, Alex

    A conference on the history of space activity was convened at Yale University in 1981 and perspectives from history, political science, journalism, politics, science, and literature were exchanged. The essays in this publication serve as the proceedings for that conference. The papers are presented in four major theme areas. These include: (1)…

  20. 77 FR 8926 - Board Meeting: March 7, 2012-Albuquerque, NM; The U.S. Nuclear Waste Technical Review Board Will...

    Science.gov (United States)

    2012-02-15

    ... Repository Geologies Pursuant to its authority under section 5051 of Public Law 100-203, the Nuclear Waste... Sheraton Albuquerque Airport Hotel, 2910 Yale Blvd. SE., Albuquerque, New Mexico 87106; (Tel) 505-843-7000; (Fax) 505-843-6307. A block of rooms has been reserved at the hotel for meeting attendees. To ensure...

  1. The Significance of the Nursery School

    Science.gov (United States)

    Gesell, Arnold

    2017-01-01

    From the standpoint of mental health and perhaps even from the standpoint of human culture, the complete realization of the educational possibilities of the preschool child is of foundational significance. Normative and comparative studies performed at a psychological clinic at Yale examining norms of development in children from one month to five…

  2. Dissociative symptoms and dissociative disorder comorbidity in patients with obsessive-compulsive disorder.

    Science.gov (United States)

    Belli, Hasan; Ural, Cenk; Vardar, Melek Kanarya; Yesılyurt, Sema; Oncu, Fatıh

    2012-10-01

    The present study attempted to assess the dissociative symptoms and overall dissociative disorder comorbidity in patients with obsessive-compulsive disorder (OCD). In addition, we examined the relationship between the severity of obsessive-compulsive symptoms and dissociative symptoms. All patients admitted for the first time to the psychiatric outpatient unit were included in the study. Seventy-eight patients had been diagnosed as having OCD during the 2-year study period. Patients had to meet the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition criteria for OCD. Most (76.9%; n = 60) of the patients were female, and 23.1% (n = 18) of the patients were male. Dissociation Questionnaire was used to measure dissociative symptoms. The Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition Dissociative Disorders interviews and Yale-Brown Obsessive Compulsive Checklist and Severity Scale were used. Eleven (14%) of the patients with OCD had comorbid dissociative disorder. The most prevalent disorder in our study was dissociative depersonalization disorder. Dissociative amnesia and dissociative identity disorder were common as well. The mean Yale-Brown score was 23.37 ± 7.27 points. Dissociation Questionnaire scores were between 0.40 and 3.87 points, and the mean was 2.23 ± 0.76 points. There was a statistically significant positive correlation between Yale-Brown points and Dissociation Questionnaire points. We conclude that dissociative symptoms among patients with OCD should alert clinicians for the presence of a chronic and complex dissociative disorder. Clinicians may overlook an underlying dissociative process in patients who have severe symptoms of OCD. However, a lack of adequate response to cognitive-behavioral and drug therapy may be a consequence of dissociative process. Copyright © 2012 Elsevier Inc. All rights reserved.

  3. Course of Tourette Syndrome and Comorbidities in a Large Prospective Clinical Study.

    Science.gov (United States)

    Groth, Camilla; Mol Debes, Nanette; Rask, Charlotte Ulrikka; Lange, Theis; Skov, Liselotte

    2017-04-01

    Tourette syndrome (TS) is a childhood-onset neurodevelopmental disorder characterized by tics and frequent comorbidities. Although tics often improve during adolescence, recent studies suggest that comorbid obsessive-compulsive disorder (OCD) and attention-deficit/hyperactivity disorder (ADHD) tend to persist. This large prospective follow-up study describes the clinical course of tics and comorbidities during adolescence and the prevalence of coexisting psychopathologies. The clinical cohort was recruited at the Danish National Tourette Clinic, and data were collected at baseline (n = 314, age range 5-19 years) and at follow-up 6 years later (n = 227) to establish the persistence and severity of tics and comorbidities. During follow-up, the Development and Well-Being Assessment (DAWBA) was used to diagnose coexisting psychopathologies. Repeated measures of severity scores were modeled using mixed effects models. Tic severity declined yearly (0.8 points, CI: 0.58-1.01, on the Yale Global Tic Severity Scale [YGTSS]) during adolescence; 17.7% of participants above age 16 years had no tics, whereas 59.5% had minimal or mild tics, and 22.8% had moderate or severe tics. Similarly, significant yearly declines in severity of both OCD (0.24, CI: 0.09-0.39, on the Yale-Brown Obsessive Compulsive Scale for Adults [Y-BOCS] and Yale-Brown Obsessive Compulsive Scale for Children [CY-BOCS]) and ADHD (0.42, CI: 0.32-0.52, DSM-IV) were recorded. At follow-up, 63.0% of participants had comorbidities or coexistent psychopathologies, whereas 37.0% had pure TS. Severity of tics, OCD, and ADHD were significantly associated with age and declined during adolescence. However, considerable comorbidities and coexisting psychopathologies persist throughout adolescence and require monitoring by clinicians. Copyright © 2017 American Academy of Child and Adolescent Psychiatry. Published by Elsevier Inc. All rights reserved.

  4. Eesti luule ja poeetika tagasivaates : vestlus Vincent B. Leitchiga / Vincent B Leitch ; küsitles [ja tõlkis ning eessõna:] Anne Lange

    Index Scriptorium Estoniae

    Leitch, Vincent B

    2002-01-01

    V. B. Leitch oli ilmumata jäänud koguteose "The poetry of Estonia: essays in comparative analysis" toimetaja. Kogumikus oleks ilmunud Yale'i ülikoolis peamiselt 1960. a-tel peetud ettekanded eesti luulest. Loengud korraldas Aleksis Rannit. V. B. Leitch meenutab ka Ants Orast, kes oli tema doktoritöö juhendaja Florida ülikoolis

  5. Oldies, Music Rights, and the Digital Age

    Science.gov (United States)

    McDonald, Peter

    2005-01-01

    The author discusses the issue of copyright, oldies, and digital preservation. He examines efforts being made to create digital sound repositories for music record prior to 1970 at such places as Yale, Syracuse, the New York Public Library, and the Library of Congress. These issues are explored by contrasting the music industry's concern for loss…

  6. Corrupting Conversations with the Marquis de Sade: On Education, Gender, and Sexuality

    Science.gov (United States)

    Greteman, Adam J.

    2016-01-01

    In this essay, the author joins a conversation started by Martin ("Reclaiming the conversation: the ideal of the educated woman." Yale University Press, New Haven, 1985) regarding gender and education seeking to extend the conversation to address sexuality. To do so, the author brings a reading of the Marquis de Sade to challenge the…

  7. Free to Teach, Free to Learn: Understanding and Maintaining Academic Freedom in Higher Education

    Science.gov (United States)

    Wildavsky, Rachel; O'Connor, Erin

    2013-01-01

    This guide for trustees reports on the dangerous decline of academic freedom and intellectual diversity on college campuses. The foreword, by Benno Schmidt, chairman of the CUNY Board of Trustees and former president of Yale, comes at a time when duly-invited graduation speakers are made unwelcome, campus speech codes threaten the free exchange of…

  8. Andrey Loginov (1977 – 2016)

    CERN Multimedia

    2016-01-01

    It is with great sadness that we learnt that Andrey, our ATLAS colleague, passed away. Andrey's passion for physics and commitment to ATLAS were only surpassed by his zest for life and his loyalty to his friends.   Andrey first came to CERN in 2006 when he was working for Yale on the ATLAS experiment. Besides his work life, he was extremely active in a multitude of different areas; he made many friends and touched many lives.   Andrey was born in 1977 in Tomsk, Russia. He received his Bs., M.S. and PhD from the Moscow Institute of Physics and Technology (MIPT). His PhD was conducted as part of the CDF Collaboration, with Henry Frisch of the University of Chicago as his research advisor. He joined Yale University in 2006 to begin working on ATLAS. Starting in 2006 he took an active role in the TRT installation and commissioning, and then turned his attention to operations and later to developing a TRT test stand. As Top Cross Section Working Group&nb...

  9. Taus at ATLAS

    Energy Technology Data Exchange (ETDEWEB)

    Demers, Sarah M. [Yale Univ., New Haven, CT (United States). Dept. of Physics

    2017-12-06

    The grant "Taus at ATLAS" supported the group of Sarah Demers at Yale University over a period of 8.5 months, bridging the time between her Early Career Award and her inclusion on Yale's grant cycle within the Department of Energy's Office of Science. The work supported the functioning of the ATLAS Experiment at CERN's Large Hadron Collider and the analysis of ATLAS data. The work included searching for the Higgs Boson in a particular mode of its production (with a W or Z boson) and decay (to a pair of tau leptons.) This was part of a broad program of characterizing the Higgs boson as we try to understand this recently discovered particle, and whether or not it matches our expectations within the current standard model of particle physics. In addition, group members worked with simulation to understand the physics reach of planned upgrades to the ATLAS experiment. Supported group members include postdoctoral researcher Lotte Thomsen and graduate student Mariel Pettee.

  10. Illumination robust face recognition using spatial adaptive shadow compensation based on face intensity prior

    Science.gov (United States)

    Hsieh, Cheng-Ta; Huang, Kae-Horng; Lee, Chang-Hsing; Han, Chin-Chuan; Fan, Kuo-Chin

    2017-12-01

    Robust face recognition under illumination variations is an important and challenging task in a face recognition system, particularly for face recognition in the wild. In this paper, a face image preprocessing approach, called spatial adaptive shadow compensation (SASC), is proposed to eliminate shadows in the face image due to different lighting directions. First, spatial adaptive histogram equalization (SAHE), which uses face intensity prior model, is proposed to enhance the contrast of each local face region without generating visible noises in smooth face areas. Adaptive shadow compensation (ASC), which performs shadow compensation in each local image block, is then used to produce a wellcompensated face image appropriate for face feature extraction and recognition. Finally, null-space linear discriminant analysis (NLDA) is employed to extract discriminant features from SASC compensated images. Experiments performed on the Yale B, Yale B extended, and CMU PIE face databases have shown that the proposed SASC always yields the best face recognition accuracy. That is, SASC is more robust to face recognition under illumination variations than other shadow compensation approaches.

  11. Growing Pains: Scaling up the Nation's Best Charter Schools. Education Sector Reports

    Science.gov (United States)

    Education Sector, 2009

    2009-01-01

    Amistad Academy is a bright shining star in public school reform. Founded in 1999 in a renovated warehouse in a blighted New Haven, Connecticut, neighborhood by a group of Yale law school students, the 289-student charter school has won the praise of the last two federal education secretaries. Educators throughout the country have traveled to the…

  12. Exploration of the Central Dogma at the Interface of Chemistry and Biology

    Science.gov (United States)

    Zhou, Alice Qinhua

    2010-01-01

    Ever since the term “central dogma” was coined in 1958, researchers have sought to control information flow from nucleic acids to proteins. Talks delivered by Drs. Anna Pyle and Hiroaki Suga at this year’s Chemical Biology Symposium at Yale in May 2010 applauded recent advances in this area, at the interface between chemistry and biology. PMID:20885900

  13. On the Science and Teaching of Emotional Intelligence: An Interview with Marc Brackett

    Science.gov (United States)

    Heller, Rafael

    2017-01-01

    Over the past two decades, researchers have gathered a wealth of evidence showing the critical roles that emotional intelligence plays in education, work, and life. But what does it look like to translate that research into practice? In this interview, Yale University's Marc Brackett takes stock of recent efforts to help K-12 educators address the…

  14. Remembering and Researching the Old and the New: An Interview with Roddy Roediger

    Science.gov (United States)

    Elmes, David G.

    2010-01-01

    Dr. Henry L. (Roddy) Roediger is the James S. McDonnell Distinguished University Professor in the Psychology Department at Washington University in St. Louis (WUSTL) and a scholar of human memory. He graduated from Washington & Lee University in 1969 and received his PhD in psychology from Yale University. He served as chair of the Psychology…

  15. Effective interactions in p-shell nuclei and the realistic interactions - I

    International Nuclear Information System (INIS)

    Upadhyaya, G.K.; Joshi, K.P.

    1984-04-01

    The effective interaction of Jain et al. derived from the Yale interaction by including the prominent core polarization diagrams is analyzed in terms of the interaction radial integrals and their spin tensor components. The interaction is also compared with some phenomenological effective interactions. The general features of the effective force in the 1 p shell region are discussed. (author)

  16. The Influence of Fathers on Young Children's Development

    Science.gov (United States)

    Pruett, Kyle D.

    2012-01-01

    Kyle D. Pruett, MD, clinical professor of child psychiatry at the Yale School of Medicine, responds to questions about the importance of engaging men in the lives of children. Dr. Pruett discusses how men parent differently than women; how mothers and fathers can effectively co-parent; the impact of parenting on the marital relationship; and the…

  17. Exploration of the Central Dogma at the Interface of Chemistry and Biology

    OpenAIRE

    Zhou, Alice Qinhua

    2010-01-01

    Ever since the term ?central dogma? was coined in 1958, researchers have sought to control information flow from nucleic acids to proteins. Talks delivered by Drs. Anna Pyle and Hiroaki Suga at this year?s Chemical Biology Symposium at Yale in May 2010 applauded recent advances in this area, at the interface between chemistry and biology.

  18. ADHD Comorbidity, Behavior, and Tic Severity

    Directory of Open Access Journals (Sweden)

    J Gordon Millichap

    2003-01-01

    Full Text Available The association of disruptive behavior with social, adaptive, and family functioning in Tourette syndrome (TS, with and without comorbid attention-deficit/hyperactivity disorder (ADHD, was evaluated in 207 children (144 boys and 63 girls between the ages of 7 and 18 years, in a study at Yale University School of Medicine, New Haven, CT.

  19. [Review of experiments measuring CP nonconservation

    International Nuclear Information System (INIS)

    Gollin, G.D.

    1985-08-01

    Recent experiments setting limits on the magnitude of the ratio of two CP nonconservation parameters epsilon'/epsilon are discussed. Gauge theory calculations suggest that epsilon'/epsilon > .005, somewhat at odds with the results epsilon'/epsilon = -.0046 +- .0058 from a Chicago-Saclay measurement and epsilon'/epsilon = .0017 +- .0082 from a Yale-BNL experiment. 9 refs., 5 figs., 2 tabs

  20. Stories about Benoit

    Science.gov (United States)

    Frame, Michael; Cohen, Nathan

    2015-03-01

    The Yale University mathematics department hosted a memorial for Benoit on April 29 and 30, 2011. The first day of the meeting consisted of three technical talks on some aspects of fractals, Benoit's principal intellectual legacy. Bernard Sapoval spoke on fractals in physics, Peter Jones on fractals in mathematics, and Nassim Taleb on fractals in finance...

  1. Tiger Moms and the Model Minority Myth

    Science.gov (United States)

    Gym, Helen

    2011-01-01

    Some months ago, Yale law professor Amy Chua wrote an op-ed for the "Wall Street Journal" that set off a media and cultural firestorm. Titled "Why Chinese Mothers Are Superior," the piece's outlandish assertions about Asian immigrant parenting hit the requisite rounds on the 24-hour news cycle. Though the media chatter was nonstop for weeks, what…

  2. Older than Snow: The "Two Cultures" and the "Yale Report" of 1828

    Science.gov (United States)

    Timmons, William Todd

    2007-01-01

    C. P. Snow's "The Two Cultures and the Scientific Revolution" represents the most famous reincarnation of a debate concerning the clash of academic cultures in higher education. This essay explores the similarities and differences in the circumstances surrounding Snow's lecture addressing a widening gap between the scientific and…

  3. All aboard!

    CERN Multimedia

    Anaïs Schaeffer

    2012-01-01

    Every year, CERN's surveyors take detailed measurements to check the alignment of the LHC components. This year, from 16 to 18 January, they took some of those measurements for the first time using a brand-new remotely controlled train in one of the long straight sections.   From left to right: Thierry Feniet, Patrick Bestmann and Cédric Charrondière in the arms of the measuring wagon. This train doesn’t take people, it takes pictures. Its purpose? To save CERN’s surveyors from having to take the alignment measurements manually, particularly in areas where operators are subject to constraints due to radioactivity (in line with the ALARA principle of keeping radiation exposure to a level that is “as low as reasonably achievable”). The surveyors’ train, over four years in development, is the joint brain-child of several groups from the EN and BE Departments. The result is a state-of-the-art device which, as Thierr...

  4. KT gets even closer to CERN people

    CERN Multimedia

    2015-01-01

    For several years, the Knowledge Transfer (KT) group has been helping CERN people to disseminate their results, know-how and technologies to new fields of application. This may be anything from working with a school, hospital or a company through a licence or collaboration agreement, to securing CERN’s intellectual property rights or even starting a company. In order to maximise the impact of CERN’s work and to provide a service adapted to its users’ needs, the KT group has launched a survey.   Assessing the needs and wishes of the CERN personnel with regard to knowledge transfer activities: this is the goal of the survey that the KT group has launched this week. “Science and engineering are key disciplines in tackling the fundamental challenges facing the planet, such as energy, security, climate change, the sustainability of natural resources and economic resilience,” says Thierry Lagrange, head of the Finance, Procurement and Knowledge Transfer...

  5. Seminar series on Safety matters

    CERN Multimedia

    HSE

    2010-01-01

    The HSE - Occupational Health & Safety and Environmental Protection - Unit is starting a seminar series on Safety matters. The aim is to invite colleagues from Universities, Industries or Government Agencies to share their experience. The seminars will take place in intervals of several months. Part of the Seminars will be held in the form of a Forum where participants can discuss and share views with persons who manage, teach or research Safety matters elsewhere. You are invited to the first Safety Seminar on 22nd September 2010 at 10h00 in building 40 S2 A1 "Salle Andersson" L’Ecole Polytechnique Fédérale de Lausanne (EPFL) will present the way safety is managed in their research institution. Some aspects of research in physics and chemical laboratories will also be presented. The seminar will be given by Dr Thierry Meyer, Head of OHS at FSB-EPFL and Dr Amela Groso, responsible for the safety of the physics institutes

  6. FRANCE AT CERN

    CERN Multimedia

    2003-01-01

    From 23 to 25 September, French industry exhibited products and technologies which are related to the field of particle physics. Twenty five companies presented their latest developments in electrical engineering, IT, vacuum & low temperature technologies, and civil engineering. Bernard Frois, Director of the Energy, Transport, and Environment Department of the French Ministry for Research and New Technologies inaugurated the exhibition on 23 September. To make the most of his visit, he also visited the assembly halls of CMS and ATLAS and the hall where the superconducting magnets for the LHC are tested. From left to right: Jean-Claude Brisson, ILO, Robert Aymar, designated CERN Director General, Françoise Le Moign, Assistant General Consul at Geneva, Alain Guillouët, Head of the economic mission in Switzerland, French Embassy, Thierry Boquien, Ubifrance, French agency for international development of companies, Bernard Frois, Director of the Department for Energy, Transport, and Environment of the Fre...

  7. Low energy nanoemulsification to design veterinary controlled drug delivery devices

    Directory of Open Access Journals (Sweden)

    Thierry F Vandamme

    2010-10-01

    Full Text Available Thierry F Vandamme, Nicolas Anton, University of Strasbourg, Faculty of Pharmacy, Illkirch Cedex, France; UMR CNRS 7199, Laboratoire de Conception et Application de Molécules Bioactives, équipe de Pharmacie Biogalénique, Illkirch Cedex, France,  This work is selected as Controlled Release Society Outstanding Veterinary Paper Award 2010Abstract: The unique properties of nanomaterials related to structural stability and quantum-scale reactive properties open up a world of possibilities that could be exploited to design and to target drug delivery or create truly microscale biological sensors for veterinary applications. We developed cost-saving and solvent-free nanoemulsions. Formulated with a low-energy method, these nanoemulsions can find application in the delivery of controlled amounts of drugs into the beverage of breeding animals (such as poultry, cattle, pigs or be used for the controlled release of injectable poorly water-soluble drugs.Keywords: nanoemulsion, nanomedicine, low-energy emulsification, veterinary, ketoprofen, sulfamethazine

  8. Winter Atomiades 2014: CERN skiers win 31 medals!

    CERN Multimedia

    CERN Bulletin

    2014-01-01

    The 12th Winter Atomiades took place at Flachau, Austria, from 8 to 15 March 2014. The event, organised by the Association of the Sports Communities of the European Research Institutes (see here), brought together 18 research centres, including CERN, AIT, ESRF, PSI and many others, with a total of about 280 participants.   Lots of fun and a great result for the 13 CERN skiers at the 2014 Winter Atomiades in Flachau, Austria. From left to right and from bottom to top: Lennart Jirden (PH), Anna Lipniacka (PH), Guillaume Michet (DGS), Vera Chetvertkova (TE), Thierry Boileau (external), Jean-Louis Grenard (EN), Clement Bovet (EN), Marc Tavlet (BE), Rob Knoops (PH), Giuseppe Lo Presti (IT), Simone Campana (IT), Sylviane Gander (external) and Javier Pablos (TE).   The team of 13 athletes from six different CERN departments won 31 medals across all disciplines, in a spirit of fun and fair play. CERN came second in the general ranking of all participating institutes! The next Winter Atomiades...

  9. THE ORIENTEERING ELITE: WORLD CHAMPIONS SINGULARITIES

    Directory of Open Access Journals (Sweden)

    Tadeu Celestino

    2015-04-01

    Full Text Available The pursuit of perfection has been one of the challenges that always was followed by the human being. Currently no one is indifferent to the systematic and exceptional performances of athletes like Cristiano Ronaldo (soccer, Simone Luder Niglli and Thierry Gueorgiou (orienteering, Usain Bolt (athletics, Michael Phelps (swimming among many others, and whose characteristics, capabilities and development paths up immediately a great admiration and curiosity to know: how they developed these abilities? What characteristics and skills makes them so exceptional? How can maintain their high performance? In this sense the results have been showing that the development of excellence in sport has its origins in childhood and it is the result of an investment and long-term commitment (Barreiros, Côté, & Fonseca, 2013. But there are few studies focusing in some manner as orienteering.Objectives: This study aims to identify characteristics and peculiarities that mark the path of a group of excellent athletes in orienteering.

  10. Take the stigma out of obesity

    African Journals Online (AJOL)

    Arun Kumar Agnihotri

    2016-03-11

    Mar 11, 2016 ... 2. de Zwaan M. Binge eating disorder and obesity. Int J Obes Relat Metab Disord. 2001;25 Suppl 1:S51-5. 3. Wang L. Weight discrimination: One size fits all remedy? Yale Law J. 2008;117(8):. 1900-45. 4. Ravussin E. Low resting metabolic rate as a risk factor for weight gain: role of the sympathetic nervous ...

  11. Looking West: Russian Perspectives of the Baltics Through the Lens of the Great Patriotic War

    Science.gov (United States)

    2017-04-13

    Road to Stalingrad: Stalin’s War With Germany . New Haven: Yale University Press, 1999. Fordham University. “Modern History Sourcebook: The...professional military writings and official statements to illustrate both change and continuity in Russian security policies towards the Baltics since World...secondary sources, as well as translated Russian professional military writings and official statements to illustrate both change and continuity in

  12. Quod licet Iovi... / Toomas Hendrik Ilves

    Index Scriptorium Estoniae

    Ilves, Toomas Hendrik, 1953-

    2006-01-01

    Raamatuarvustus: Fukuyama, Francis. America at the Crossroads: Democracy, Power, and the Neoconservative Legacy. New Haven ; London : Yale University Press, 2006. Ameerika Ühendriikide neokonservatiivse välispoliitika analüüs, uuskonservatismi sünd ja selle vaimsed allikad; ennetava sõja kontseptsiooni mõju väikeste riikide julgeolekule. Ilmunud ka: Sirp : Diplomaatia 12. mai 2006 nr. 6 (33), lk. 2-4.

  13. Images, Imagination and Impact: War in Painting and Photography from Vietnam to Afghanistan

    Science.gov (United States)

    2013-06-01

    the United 66 Lawrence Freedman, Kennedy’s Wars: Berlin, Cuba , Laos, and Vietnam (New York: Oxford...had solid anti-Nazi legacies. Thus, especially postwar philosophy in Germany was influenced by Marxism as a clear counter-reaction to National...165. New Haven: Yale University Press, 1993. Freedman, Lawrence. Kennedy’s Wars: Berlin, Cuba , Laos, and Vietnam. New York: Oxford University Press

  14. An Investigation of Loss of Control Eating Disorder in Children

    Science.gov (United States)

    2010-02-19

    syndrome eating disorders in adulthood ( Kotler , Cohen, Davies, Pine, & Walsh, 2001). For this reason, early identification of pathological overeating...eating (Iancu, Cohen, Ben Yehuda, & Kotler , 2006; Schmidt, Jiwany, & Treasure, 1993). Such research indicates that alexithymia may be a stable trait...CT: Yale University. Iancu, I., Cohen, E., Ben Yehuda, Y., & Kotler , M. (2006). Treatmetn of eating disorders improves eating symptoms but not

  15. Louis Kahni mateeria, valguse ja energia arhitektuur = Louis Kahn's Architecture of Matter, Light and Energy / Anne Griswold Tyng ; tõlk. Tiina Randus

    Index Scriptorium Estoniae

    Tyng, Anne Griswold

    2007-01-01

    Louis Kahni betoonarhitektuurist (Weissi maja, 1947-1949), Yale'i kunstigaleriist (1951-1953), City Toweri projektist (1952-1958), Trentoni supelmajast (1954-1956), Salki instituudist (1959-1965, La Jolla, California), Kimbelli kunstimuuseumist (1968-1974), pealinnakompleksist Dhakas (1965-1974). Anne Griswold Tyng hakkas L. Kahni juures tööle 1945. a., tema algkooli projektist (1949-50), oma Philadelphia maja juurdeehitusest (1965-1968)

  16. Assignment Problem for the U.S. Marine Corps: Regional, Culture, and Language Familiarization Program

    Science.gov (United States)

    2013-12-01

    stations, such as rank, experience, duty preference, or gender . Prior to developing the MSGAT, the assignment personnel would have to manually assign...Zimbabwe, Zambia Mongolia, China , Japan, North Korea, South Korea, Chinese 14. Northeast Asia 10% (Mandarin), Taiwan Korean Brunei Darussalam...from: http://opensolver.org/. 68 Reinhardt, U. E. (1992). Reflections on the meaning of efficiency: Can efficiency be separated from equity ? Yale

  17. Robust Membranes for Sustainable Wastewater Treatment by Forward Osmosis in FOBs

    Science.gov (United States)

    2017-05-09

    ADDRESS(ES) 8. PERFORMING ORGANIZATION REPORT NUMBER Yale University Department of Chemical & Environmental Engineering 17 Hillhouse Avenue New Haven...membrane processes (ODMPs) hold significant promise in augmenting water supplies using seawater and wastewater [5, 6]. The potential of engineered ...membrane surface with low functional group density, as membrane surface chemistry and morphology are known to be heterogeneous [46, 47]. FO membranes

  18. Aripiprazole versus risperidone for treating children and adolescents with tic disorder: a randomized double blind clinical trial.

    Science.gov (United States)

    Ghanizadeh, Ahmad; Haghighi, Alireza

    2014-10-01

    There are some uncontrolled studies about the efficacy and safety of both aripiprazole and risperidone for treating tic disorder. Moreover, the efficacy of these medications has never been compared. This is the first double blind randomized clinical trial comparing the safety and efficacy of aripiprazole and risperidone for treating patients with tic disorder. Sixty children and adolescents with tic disorder were randomly allocated into one of the two groups to receive either aripiprazole or risperidone for 2 months. The primary outcome measure was the score of Yale Global Tic Severity Scale. In addition, health related quality of life and adverse events were assessed. Both aripiprazole and risperidone decreased the Yale Global Tic Severity Scale score during this trial. Moreover, both medications increased the health related quality of life score. Both aripiprazole and risperidone were tolerated well. Aripiprazole [3.22 (1.9) mg/day] decreased tic score as much as risperidone [0.6 (0.2) mg/day]. Their adverse effects and their effects on health related quality of life were comparable. However, risperidone increased the patients' social functioning more than aripiprazole in short term.

  19. Tic-related cognition, sensory phenomena, and anxiety in children and adolescents with Tourette syndrome.

    Science.gov (United States)

    Steinberg, Tamar; Harush, Adva; Barnea, Meirav; Dar, Rueven; Piacentini, John; Woods, Doug; Shmuel-Baruch, Sharona; Apter, Alan

    2013-07-01

    Tourette syndrome is a protoypical example of developmental psychopathology, with the varying expressions of the disorder and its consequences appearing over time. Sensory urges typically appear after age 10 and are often followed by anxiety and depression. To study the associations among tic-related cognitions, premonitory urges, and tic severity in children with Tourette syndrome at different stages of the illness. Fifty-seven consecutive patients referred to a tic disorders clinic. A battery of instruments was completed: Yale Global Tic Severity Scale, Premonitory Urge for Tics Scale, Screen for Child Anxiety Related Emotional Disorders, and Child Depression Inventory. To examine cognitions, a new measure was developed: the Beliefs About Tics Scale. Strong correlations were found between tic-related beliefs and both premonitory urges and tic-related impairments (as measured by the Yale Global Scale). Tic-related beliefs were also strongly correlated with depression in children older than 13 years but not in younger children. The significant correlations between tic-related cognitions, premonitory urges, and tic-related impairments in children emphasize the important role of psychological and sensory factors in the understanding of Tourette syndrome and in its treatment. Copyright © 2013 Elsevier Inc. All rights reserved.

  20. Reminiscences of a journeyman scientist: studies of thermoregulation in non-human primates and humans.

    Science.gov (United States)

    Adair, Eleanor Reed

    2008-12-01

    After graduating from Mount Holyoke College in 1948 where I majored in experimental psychology I worked at the College for 2 years with the Johns Hopkins Thermophysiological Unit. My graduate work later at the University of Wisconsin, centering on sensory psychology, culminated in my 1955 PhD thesis on human dark adaptation. I continued work in sensory psychology later with Neal Miller at Yale and then moved to the John B. Pierce Foundation--a Yale affiliate--where I began the studies of thermoregulation that constitute the center of my scientific career. Those studies were largely--later wholly--conducted using microwave energy as a thermal load and were thus published in Bioelectromagnetics even as I played an active role in the Bioelectromagnetics Society. In the beginning this work was centered on the responses of Squirrel Monkeys to thermal loads. Later, serving as Senior Scientist at the Air Force Research Laboratory at San Antonio, I completed an extensive analysis of thermal regulation in humans. I consider this work of special note inasmuch as the extraordinary human thermoregulatory ability was surely among the attributes that were paramount in initially separating humans from the other anthropoid primates.

  1. A Novel Approach of Low-Light Image Denoising for Face Recognition

    Directory of Open Access Journals (Sweden)

    Yimei Kang

    2014-04-01

    Full Text Available Illumination variation makes automatic face recognition a challenging task, especially in low light environments. A very simple and efficient novel low-light image denoising of low frequency noise (DeLFN is proposed. The noise frequency distribution of low-light images is presented based on massive experimental results. The low and very low frequency noise are dominant in low light conditions. DeLFN is a three-level image denoising method. The first level denoises mixed noises by histogram equalization (HE to improve overall contrast. The second level denoises low frequency noise by logarithmic transformation (LOG to enhance the image detail. The third level denoises residual very low frequency noise by high-pass filtering to recover more features of the true images. The PCA (Principal Component Analysis recognition method is applied to test recognition rate of the preprocessed face images with DeLFN. DeLFN are compared with several representative illumination preprocessing methods on the Yale Face Database B, the Extended Yale face database B, and the CMU PIE face database, respectively. DeLFN not only outperformed other algorithms in improving visual quality and face recognition rate, but also is simpler and computationally efficient for real time applications.

  2. A randomized controlled trial comparing EMDR and CBT for obsessive-compulsive disorder.

    Science.gov (United States)

    Marsden, Zoe; Lovell, Karina; Blore, David; Ali, Shehzad; Delgadillo, Jaime

    2018-01-01

    This study aimed to evaluate eye movement desensitization and reprocessing (EMDR) as a treatment for obsessive-compulsive disorder (OCD), by comparison to cognitive behavioural therapy (CBT) based on exposure and response prevention. This was a pragmatic, feasibility randomized controlled trial in which 55 participants with OCD were randomized to EMDR (n = 29) or CBT (n = 26). The Yale-Brown obsessive-compulsive scale was completed at baseline, after treatment and at 6 months follow-up. Treatment completion and response rates were compared using chi-square tests. Effect size was examined using Cohen's d and multilevel modelling. Overall, 61.8% completed treatment and 30.2% attained reliable and clinically significant improvement in OCD symptoms, with no significant differences between groups (p > .05). There were no significant differences between groups in Yale-Brown obsessive-compulsive scale severity post-treatment (d = -0.24, p = .38) or at 6 months follow-up (d = -0.03, p = .90). EMDR and CBT had comparable completion rates and clinical outcomes. Copyright © 2017 John Wiley & Sons, Ltd.

  3. Applied Nanotechnology and Nanoscience International Conference 2016

    International Nuclear Information System (INIS)

    2017-01-01

    Introduction:The Applied Nanotechnology and Nanoscience International Conference is an annual event that hosts high-profile plenary speakers, world class researchers, oral and poster presentations, workshops, sponsor exhibits and extra activities to network.This conference is held in a different European country each year and the number of participants is growing very quickly. ANNIC 2016 was held in Barcelona and hosted delegates from 47 different countries, it was a great opportunity for the attendees to share their research findings with wide audience, promote knowledge exchange and network.Main Sponsor: NFFA (nffa.eu) Chairs Committee:• Prof. Joan Ramon Morante (Catalonia Institute for Energy Research (IREC), Spain)• Prof. Jordi Arbiol (ICREA and Catalan Institute of Nanoscience and Nanotechnology (ICN2), CSIC and The Barcelona Institute of Science and Technology (BIST), Catalonia, Spain)• Prof. Arben Merkoçi (ICREA and Catalan Institute of Nanoscience and Nanotechnology (ICN2), Catalonia, Spain)• Prof. Alberto Vomiero (Luleå University of Technology, Sweden)Guest Editor Committee• Dr. Yian Tai, National Taiwan University of Science and Technology, Taiwan• Dr. Sabherwal Priyanka, Institute of Nano Science and Technology, IndiaReviewers Committee:• Laura M Lechuga, Spain• Fernando Torres Andón, Italy• Pablo Alonso-González, Spain• Fabrice P. Laussy, Spain• Toby Hallam, Ireland• Robert S Maxwell, United States• Olivier Soppera, France• Bouraoui Ilahi, Saudi Arabia• Thierry Baron, France• Brent Wagner, United States• Sergey A. Maksimenko, Belarus• Luigi Sirleto, Italy• Alexander Obraztsov, Russian Federation• Maria Tchernycheva, France• Daniel Granados, Spain• Juan P. Martínez-Pastor, Spain• Blas Garrido, Spain• Felix Casanova, Spain• Rongping Wang, Australia• Daniele Sanvitto, Italy• David Cox, United Kingdom• Kadic Muamer, Germany• Amitav Sanyal, Turkey• Jan Honolka, Czech Republic• Andrea Liscio

  4. Temporal Reasoning and Default Logics.

    Science.gov (United States)

    1985-10-01

    Aritificial Intelligence ", Computer Science Research Report, Yale University, forthcoming (1985). . 74 .-, A Axioms for Describing Persistences and Clipping...34Circumscription - A Form of Non-Monotonic Reasoning", Artificial Intelligence , vol. 13 (1980), pp. 27-39. [13] McCarthy, John, "Applications of...and P. J. Hayes, "Some philosophical problems from the standpoint of artificial intelligence ", in: B. Meltzer and D. Michie (eds.), Machine

  5. Interinstitutional collaboration for end-user bioinformatics training: Cytoscape as a case study

    Directory of Open Access Journals (Sweden)

    Marci D. Brandenburg, MS, MSI

    2017-04-01

    Conclusions: This collaboration furthered the U-M bioinformationist’s role in the field as an expert in Cytoscape instruction, while also establishing the CWML as a leader in providing support for analyzing and visualizing molecular data at Yale University. The authors found this collaboration to be a successful way for librarians to fill end-user training gaps in rapidly changing fields such as bioinformatics.

  6. Natural Tasking of Robots Based on Human Interaction Cues

    Science.gov (United States)

    2005-06-01

    MIT. • Matthew Marjanovic , researcher, ITA Software. • Brian Scasselatti, Assistant Professor of Computer Science, Yale. • Matthew Williamson...2004. 25 [74] Charlie C. Kemp. Shoes as a platform for vision. 7th IEEE International Symposium on Wearable Computers, 2004. [75] Matthew Marjanovic ...meso: Simulated muscles for a humanoid robot. Presentation for Humanoid Robotics Group, MIT AI Lab, August 2001. [76] Matthew J. Marjanovic . Teaching

  7. A Framework of Organizational Empowerment for Strategic Military Leaders

    Science.gov (United States)

    2012-03-22

    Empowerment, Performance , and Satisfaction ,” The Academy of Management Journal 47, no. 3 (June 2004): 332. 63 Ibid, 333. 64 Ibid, 334. 65 Ibid, 335. 66...5f. WORK UNIT NUMBER 7. PERFORMING ORGANIZATION NAME(S) AND ADDRESS(ES) AND ADDRESS(ES) 8. PERFORMING ORGANIZATION REPORT...military culture. The person with authoritative power may make unilateral decisions or involve participation by stakeholders. Victor Vroom from Yale

  8. Free Books for Everyone! | Poster

    Science.gov (United States)

    Last year, scientists from Yale University published the results of a study showing that people who read books for at least 30 minutes each day may live almost two years longer than people who don’t read. It’s the perfect reason to visit the 17th Annual Book & Media Swap at the Scientific Library, where you can pick up free books during the month of November.

  9. Fractals and humor

    Science.gov (United States)

    Martin, Demetri

    2015-03-01

    Demetri Maritn prepared this palindromic poem as his project for Michael Frame's fractal geometry class at Yale. Notice the first, fourth, and seventh words in the second and next-to-second lines are palindromes, the first two and last two lines are palindromes, the middle line, "Be still if I fill its ebb" minus its last letter is a palindrome, and the entire poem is a palindrome...

  10. SMARTScience Tools: Interacting With Blazar Data In The Web Browser

    Science.gov (United States)

    Hasan, Imran; Isler, Jedidah; Urry, C. Megan; MacPherson, Emily; Buxton, Michelle; Bailyn, Charles D.; Coppi, Paolo S.

    2014-08-01

    The Yale-SMARTS blazar group has accumulated 6 years of optical-IR photometry of more than 70 blazars, mostly bright enough in gamma-rays to be detected with Fermi. Observations were done with the ANDICAM instrument on the SMARTS 1.3 m telescope at the Cerro Tololo Inter-American Observatory. As a result of this long-term, multiwavelength monitoring, we have produced a calibrated, publicly available data set (see www.astro.yale.edu/smarts/glast/home.php), which we have used to find that (i) optical-IR and gamma-ray light curves are well correlated, supporting inverse-Compton models for gamma-ray production (Bonning et al. 2009, 2012), (ii) at their brightest, blazar jets can contribute significantly to the photoionization of the broad-emission-line region, indicating that gamma-rays are produced within 0.1 pc of the black hole in at least some cases (Isler et al. 2014), and (iii) optical-IR and gamma-ray flares are symmetric, implying the time scales are dominated by light-travel-time effects rather than acceleration or cooling (Chatterjee et al. 2012). The volume of data and diversity of projects for which it is used calls out for an efficient means of visualization. To this end, we have developed a suite of visualization tools called SMARTScience Tools, which allow users to interact dynamically with our dataset. The SMARTScience Tools is publicly available via our webpage and can be used to customize multiwavelength light curves and color magnitude diagrams quickly and intuitively. Users can choose specific bands to construct plots, and the plots include features such as band-by-band panning, dynamic zooming, and direct mouse interaction with individual data points. Human and machine readable tables of the plotted data can be directly printed for the user's convenience and for further independent study. The SMARTScience Tools significantly improves the public’s ability to interact with the Yale-SMARTS 6-year data base of blazar photometry, and should make

  11. Improving recovery time following heart transplantation: the role of the multidisciplinary health care team

    Directory of Open Access Journals (Sweden)

    Roussel MG

    2013-08-01

    Full Text Available Maureen G Roussel,1 Noreen Gorham,2 Lynn Wilson,2 Abeel A Mangi2 1Heart and Vascular Center, Yale-New Haven Hospital, New Haven, CT, USA; 2Center for Advanced Heart Failure, Mechanical Circulatory Support and Cardiac Transplantation, Yale New Haven Heart and Vascular Institute, Yale-New Haven Hospital, New Haven, CT, USA Background: The care of cardiac transplant patients is complex requiring a finely orchestrated endeavor to save a patient’s life. Given the chronic and complex nature of these patients, multiple disciplines are involved in their care. Recognizing difficulties with communication among team members and striving for improved efficiencies in our pretransplant listing process and in our inpatient care, our team was prompted to change the existing approach to patient care related to heart transplantation. Methods: Daily multidisciplinary rounds were instituted and the format of the weekly Multidisciplinary Review Committee (MDRC meetings was modified with the list of attendees broadened to include a larger interdisciplinary team. Additionally, the approach to patient care was analyzed for process improvement. Results: The quality improvements are improved communication and throughput, quantified in an 85% decrease in time to complete transplant evaluation, a 37% decrease in median length of stay posttransplantation, and a 33% reduction in the 30 day readmission rate. In addition, pre- and posttransplant caregivers now participate in MDRC in person or via an electronic meeting platform to support the continuum of care. Quality metrics were chosen and tracked via a transparent electronic platform allowing all involved to assess progress toward agreed upon goals. These were achieved in an 18 month time period following the recruitment of new leadership and invested team members working together as a multidisciplinary team to improve the quality of cardiac transplant care. Discussion: Implementation of daily multidisciplinary rounds and

  12. Thierry Fabre et Robert Ilbert (eds Les représentations de la Méditerranée, Maisonneuve Larose, Paris, 2000.

    Directory of Open Access Journals (Sweden)

    Pierre Vergès

    2005-01-01

    Full Text Available Un nouveau livre sur la Méditerranée ? Non, un ensemble de livres, enserrés dans un beau coffret, qui donnent la parole à dix pays , chacun représenté par un écrivain et un scientifique. Œuvre collective, parole plurielle pour montrer que la " représentation " de la Méditerranée est aussi importante que sa réalité géographique, économique et politique. Ce parti pris est courageux dans notre univers où la matérialité économique devient un langage dominant. Ce coffret est le fruit d'un programm...

  13. An Arab NATO in the Making Middle Eastern Military Cooperation Since 2011

    Science.gov (United States)

    2016-09-01

    more pressing every day.”43 King Hamad of Bahrain shortly thereafter backed this call, whereas Tunisia’s foreign minister called it “neither...ava- lon.law.yale.edu/20th_century/arabjoin.asp. 6. Helene von Bismarck, British Policy in the Persian Gulf, 1961-1968: Conceptions of Informal...military cooperation deal,” BBC Monitoring, September 25, 2014; Ammun News website, “ King Abdullah attends joint Jordanian-Emirati military drill

  14. How Critical Is Critical Infrastructure?

    Science.gov (United States)

    2015-09-01

    manager conducting a risk self-assessment will likely be subconsciously biased to assess greater risks than actually exist. This problem can be... bias .” The optimism bias extends beyond MBA students. People under estimate their risk for car accidents, think the chances of divorce are low, and...Decisions about Health, Wealth, and Happiness (New Haven, CT: Yale University Press, 2008), 20. 29 others.80 Optimism bias is evident in compulsive

  15. Relations Between Executive Functions and Different Symptomatic Dimensions in Obsessive Compulsive Disorder

    OpenAIRE

    Pedron, Ana Cristina; Ferrão, Ygor Arzeno; Gurgel, Léia Gonçalves; Reppold, Caroline Tozzi

    2015-01-01

    There is no consensus in the literature as to neuropsychological functioning, the severity of obsessive-compulsive symptoms (OCS) and the definitions of the OCS dimensions. We conducted a cross-sectional study investigating the relationship between executive function and OCS severity in the various dimensions, according to the Dimensional Yale-Brown Obsessive-Compulsive Scale criteria. We evaluated 28 patients with OCS, using eight neuropsychological instruments to evaluate executive function...

  16. Annotated Bibliography on the Physiological Effects of Acceleration in Aircraft.

    Science.gov (United States)

    1945-09-01

    pulse wave deflection was reduced and the dicrotic notch was deepened. d. The size of the cardiac silhouette was reduced in all subjects during the...gradient and single pressure suits; arterial occlusion suit; p-essure transmission factors in suits; pneumatic lever suit... factors in anti-"g" suits. (Yale) CAM No. 129. 10 Dec. 42. a, Directly underneath pressurizing air bladders, the pressure is the same as in the

  17. Gordon Research Conference in Organometallic Chemistry, held August 16-20, 1982 Andover, New Hampshire.

    Science.gov (United States)

    1983-03-01

    A. Gentile, Gerald B. Ansell , Michelle A. Modrik ad "S-usan Zentz, Exxon Research and Engineering Co., "Bimetallic Titanium/Molybdenum Complexes...Fluxional M. Moskovits molecules with Multiple Bonding" University of Toronto "Clusters in Catalysis" Basic Steps as Revealed R. Adam by Triosmium...Andover, N.H. August 16-20, 1982 REGISTRATION LIST Adams , Richard D. Farm 1 Bleeke, John John Yale University Washington University 225 Prospect St

  18. An I for an Eye: Personal Narrative and the Great War

    Science.gov (United States)

    1989-05-10

    A number of good overviews of reader-response and reception theory are available: see especially Susan R. Sulieman and Inge Crosman, eds. The Reader...Reader (1987), and Robert C. Holub’s critical introduction to reception theory , Reception Theory (1984). For a recent additions to the debate, see Inge...Yale UP, 1967. Holub, Robert C. Reception Theory : A Critical Introduction. London: Metheun, 1984. 247 Hoy, David Couzens. The Critical Circle

  19. Report of the Information Technology Workshop

    Science.gov (United States)

    1983-10-01

    computer sci- ence and related fields. Th-se demographics result in 8.0 PRIORITIES sharpl ) increased demand for both faculty and technologi- The problem...Universities scripts for NL representation. The following universities are active in NL: Columbia University ( Mike Lebowitz. Cathy McKeown) Yale (Roger...Bruce beat environment for NL research; anything less will mean Buchanan, Mike Genesreth. The Heuristic Program- that progress is slower than it could

  20. Frequency and Correlates of Suicidal Ideation in Pediatric Obsessive-Compulsive Disorder

    OpenAIRE

    Storch, Eric A.; Bussing, Regina; Jacob, Marni L.; Nadeau, Joshua M.; Crawford, Erika; Mutch, P. Jane; Mason, Dana; Lewin, Adam B.; Murphy, Tanya K.

    2015-01-01

    This study examined the frequency and sociodemographic and clinical correlates of suicidal ideation in a sample of children and adolescents with obsessive-compulsive disorder (OCD). Fifty-four youth with OCD and their parent(s) were administered the Schedule for Affective Disorders and Schizophrenia for School-Age Children-Present and Lifetime, Children’s Yale-Brown Obsessive Compulsive Scale, and Children’s Depression Rating Scale-Revised. Children completed the Suicidal Ideation Questionnai...

  1. The Therapeutic Effect of the Antitumor Drug 11 Beta and Related Molecules on Polycystic Kidney Disease

    Science.gov (United States)

    2017-10-01

    models (Somlo, Yale). Preparation work to assemble a collection of probes specific for oxidative stress genes and other PKD specific genes (as part... Worked : 6 Contribution to Project: Performance of experiments including those related to mitochondrial biology in vivo and unfolded protein...1 AWARD NUMBER: W81XWH-15-1-0364 TITLE: THE THERAPEUTIC EFFECT OF THE ANTITUMOR DRUG 11 BETA AND RELATED MOLECULES ON POLYYSTIC KIDNEY DISEASE

  2. New Challenges in Cross Domain Deterrence

    Science.gov (United States)

    2018-06-01

    to obscure the identity of the instigator of a conflict. The uniforms worn by insurgents, the weapons issued to them, social media postings...of the insti- gator. Software might be developed to expose social media trolls from the cyber domain that are being employed for the purposes of...and Influence , New Haven, Conn.: Yale University Press, 1966. Social Security Administration, Office of the Inspector General, The Social Security

  3. North-American MP Tandem accelerators

    International Nuclear Information System (INIS)

    Wegner, H.E.; Thieberger, P.

    1977-01-01

    There are six North-American MP Tandem accelerators: Yale; Minnesota; Chalk River; Rochester; and two at Brookhaven. The current status and operating characteristics of these six tandem accelerators are discussed. Upgrade and special improvements of the different machines is reviewed and new developments since the last Electrostatic Conference are discussed in detail. The overall operating characteristics of the different machines during the last year of operation are compared

  4. Copper Oxide (CuO) 2-D Nanosheets for Advanced Electronic and Optical Properties

    Science.gov (United States)

    2015-08-01

    supercritical CO2 reactor is in progress. The reactor is being machined and experiments will begin September 1. 5. Transport measurements on pellets made...for the upgrading of biodiesel . In a collaboration with Professor Kim at Yale we have decorated CuO nanosheets with nanodiamonds as a new catalytic...and transport electrons like a conduit. In order to maximize the photocatalytic activity of ND/photocatalyst composites, the electrical conductivity of

  5. Snapshots to shed light on LHC performance

    CERN Multimedia

    2006-01-01

    With the impressive size and unprecedented power of the LHC, it is all too easy to overlook the smaller devices that have the difficult task of monitoring the new accelerator. You don't have to stand too far back from the big picture to see examples of clever technology inside the LHC. One of the undulators installed in the LHC tunnel can be seen on the right of the photo. From right to left, back row: Lucio Rossi (group leader, MCS), Davide Tommasini (conceptual design, MCS), Thierry Tenaglia (integration design,TS-MME), Remo Maccaferri (project leader, MCS) and Hans Kummer (MCS/ME); front row: Gilles Trachez (MCS-ME) and Bruno Meunier (FSU-AT12). In contrast to the usual articles about the LHC's big number statistics, examples of clever problem-solving found in beam monitoring machinery show that smaller things can be beautiful too. The design of the LHC accelerator brought new challenges for monitoring the shape of the particle beam, known as the beam profile. The size of the beam shrinks as higher energi...

  6. CERN in 2030

    CERN Multimedia

    Laëtitia Pedroso

    2011-01-01

    A competition will soon be launched to select the architect, urban planner or landscape designer to undertake the first phase of redevelopment of the parking area by the flagpoles, between Entrances A and B. This will be the first stage in a wider development project aimed at sprucing up the CERN site and enhancing its image. Work to create a pleasant and harmonious area at the CERN entrance will start in 2013 while preparatory work for other developments inside the CERN site has already begun…   CERN as it is today.  By 2030, CERN will be a greener place, much like a university campus. The arrival of the tramway on 30 April will be an opportunity to forge ahead with the urban plan aimed at rejuvenating the CERN site and redefining how it is organised. "Nearly sixty years after CERN's first buildings went up, this plan will help transform the site and give it a welcoming, friendly face, a bit like a university campus," explains Thierry Chanard, urban plannin...

  7. Meeting of Directors and Heads of Department from CEA-Saclay, France

    CERN Multimedia

    Patrice Loïez

    2002-01-01

    Directors and Heads of Department from the Saclay centre of the French atomic energy commission (CEA) visited CERN in December. They are pictured here at the LHC magnet test facility in building SM18. On the left behind the visitors are the test benches where magnets are prepared for installation in String 2: the 120-metre full-scale model of an LHC cell of the regular part of the arc, which can be seen to the right. Photos 01, 02: Left to right: Marc Dejardin, Alain Givernaud, Louis Laurent, François Kircher, Antoine Masurel, Joël Feltesse, André Menez, T. Taylor, Philippe Pradelles, Bernard Sevestre, Michel Roche, Jean-Yves Gascoin, Thierry Lieven, Michel Spiro, Jean-Pierre Pervès, Yves Lemoigne, Béatrice Reder, Georges Carola, Philippe Lebrun, Yves Bourlat, Bertrand Mercier, Jean-Paul Langlois, Patrick Laurent, Didier Moulin, Xavier Vitart, Marc Serre, Jean-Louis Pierrey, Patrick Jarry, Bruno Mansoulié, Stéphane Lequien, Hervé Barbelin, Philippe Pallier, Jean-Yves Guillamot, and Norbert Sioegel.

  8. Building 887: An Aladdin's Cave for Physicists

    CERN Multimedia

    2001-01-01

    Building 887 on the Prévessin site is home to numerous experiments bringing together physicists and engineers from around the world. Its diversity makes the huge building a replica of CERN in miniature. The Installation unit of the SL EA group in front of the support structure for the ATLAS muon chambers. From left to right, seated: Pierre Gimenez, Yves Bonnet, Yves Naveau, Alain Pinget, Christian Becquet, Camille Adenot; standing: Philippe Guillot, Thierry Reynes, Monserrat Zurita-Perez, Claude Ferrari et Denis Gacon. The big wheel to be used for the ATLAS muon chambers (see below) is much the most spectacular installation currently occupying Building 887. But it is far from being the only attraction. Push open the heavy doors of this immense hall and it is a bit like entering a physicists' Aladdin's cave. The building, 55 metres wide and 300 metres long, is a treasure trove of engineering and technology, a CERN in miniature, housing dozens of collaborations from all over the world. With its 150...

  9. Management of persistent occiput posterior position: a substantial role of instrumental rotation in the setting of failed manual rotation.

    Science.gov (United States)

    Guerby, Paul; Allouche, Mickael; Simon-Toulza, Caroline; Vayssiere, Christophe; Parant, Olivier; Vidal, Fabien

    2018-01-01

    To compare the maternal and neonatal outcomes associated with Instrumental Rotation (IR) to operative vaginal delivery in occiput posterior (OP) position with Thierry's spatulas (TS), in the setting of failed manual rotation (MR). We led a prospective observational cohort study in a tertiary referral hospital in Toulouse, France. All women presenting in labor with persistent OP position at full cervical dilatation and who delivered vaginally after failed MR and with IR or OP assisted delivery were included from January 2014 to December 2015. The main outcomes measured were maternal morbidity parameters including episiotomy rate, incidence and severity of perineal lacerations, perineal hematomas and postpartum hemorrhage. Severe perineal tears corresponded to third and fourth degree lacerations. Fetal morbidity outcomes comprised neonatal Apgar scores, acidemia, fetal injuries, birth trauma and neonatal intensive care unit admissions. Among 9762 women, 910 (9.3%) presented with persistent OP position at full cervical dilatation and 222 deliveries were enrolled. Of 111 attempted IR, 97 were successful (87.4%). The incidence of anal sphincter injuries was significantly reduced after IR attempt (1.8% vs. 12.6%; p manual rotation.

  10. Staff members with 25 years’ service at CERN in 2007

    CERN Multimedia

    HR Department

    2007-01-01

    The 24 staff members who have spent 25 years within CERN in 2007 were invited by the Director-General to a reception in their honour on 11 October. Mr.\tBLEUS Baudouin\tAB Mr.\tBRUNEL Bernard\tPH Mr.\tCAILLET Norbert\tHR Dr.\tCASPERS Friedhelm\tAB Mr.\tCHEVRET Thierry\tTS Mr.\tCUMER Gérard\tTS Mrs.\tDA COSTA Maryse\tIT Mrs.\tDELAMARE Catherine\tIT Mr.\tERIKSSON Tommy\tAB Mrs.\tFOFFANO Susan\tIT Mr.\tGONZALEZ José Luis\tAB Mr.\tHUTCHINS Stephen\tAB Dr.\tKLEMPT Wolfgang\tPH Mr.\tLEVRIER François\tTS Dr.\tMARCHIORO Alessandro\tPH Mr.\tNORMANN Lasse\tAB Dr.\tRAICH Ulrich\tAB Mr.\tREBUT Michel\tPH Mr.\tRUSSO Aniello\tAT Dr.\tSTAMPFLI Lorenz\tDSU Mrs.\tTUUVA Martine\tTS Dr.\tWEISZ Sylvain\tTS Mr.\tYVON Guy\tAB Mr.\tZIEGLER Patrice\tTS

  11. Pourquoi les étoiles brillent-elles ? - French version only

    CERN Multimedia

    2005-01-01

    Quelles réalités se cachent derrière des mots mystérieux comme pulsars ou trous noirs ? Les 8 et 9 juin, l'Ecole Polytechnique Fédérale de Lausanne (EPFL) et l'Université de Genève (UniGE) organisent des conférences sur l'astrophysique destinées au grand public. L'entrée est libre. Chaque soir, trois exposés successifs : L'homme qui a compris pourquoi brillent les étoiles... par le Professeur André Maeder, Observatoire de Genève, UniGE. Pulsars et trous noirs par le Professeur Thierry Courvoisier, Observatoire de Genève,UniGE. Preuves du Big-Bang par le Professeur Georges Meylan, Laboratoire d'Astrophysique, EPFL . Le 8 juin 2005, de 18h à 20h, Auditoire CO1, EPFL, Ecublens Le 9 juin 2005, de 18h à 20h, Auditoire Rouiller, Uni-Dufour, Genève Renseignements : 022 379 22 00 Impression artistique d'un pulsar et de son étoile compagnon. Crédit : ESA/Francesco Ferraro (Bologna Astronomical Observatory)

  12. O desenvolvimento dos "Diagnosis Related Groups"- DRGs. Metodologia de classificação de pacientes hospitalares The development of "Diagnosis Related Groups" - DRGs, a methodology for classifying hospital patients

    Directory of Open Access Journals (Sweden)

    Marina F. Noronha

    1991-06-01

    Full Text Available É descrito o processo de desenvolvimento do sistema de classificação de pacientes internados em hospitais que atendem casos agudos, denominada Diagnosis Relatd Group - DRGs, desenvolvido e difundido por pesquisadores da Universidade de Yale, USA. Esse sistema vem a ser um instrumento que permite a mensuração do produto hospitalar, principalmente sob o ponto de vista gerencial. São apresentadas considerações acerca do que é entendido como produto hospitalar, seguindo nos meandros do desenvolvimento dos primeiros DRGs, até a mais recente revisão do sistema. É descrita sua utilização em alguns países e diversos usos potenciais desse sistema, que abrangem desde o uso para pagamento a instrumento de controle de qualidade.The history of Diagnosis Related Groups (DRG's, a system for classifying patients in acute care hospitals, developed by researchers at Yale University, USA, is reviewed. DRGs are an instrument for measuring the hospital product, primarily from a management viewpoint. Starting with a review of the definitions of hospital product, the article follows the course from the first DRGs through the most recent revision, providing a summary of potential and current applications of the system in several countries, which range from payment mechanism to uses in quality control.

  13. Unspeakable Silences, When Poetry Ceases to be a Luxury, Black Tulips, My Eggs

    Directory of Open Access Journals (Sweden)

    Melissa A Castillo-Garsow

    2013-09-01

    Full Text Available Melissa Castillo-Garsow is a Mexican-American writer, journalist, and scholar currently pursuing a PhD in American Studies and African American Studies at Yale University. Her short stories and poetry have been published in various journals including The Acentos Review, La Bloga, Hispanic Culture Review, and Hinchas de Poesia. Her first novel, Pure Bronx, co-written with Fordham Professor Mark Naison, is due for release Oct. 2013 from Augustus Publishing. Melissa completed her Master’s degree in English with a concentration in Creative Writing at Fordham University in 2011. Prior to that she was awarded a Bachelor of Arts from New York University summa cum laude with a double major in Journalism and Latin American Studies. A former employee of NBC News, El Diario/ La Prensa and Launch Radio Networks, Melissa has had articles and reviews published in a wide variety of forums including CNN.com, Latin Beat Magazine, University Wire, El Diario/La Prensa, Women’s Studies, Words. Beats. Life: The Global Journal of Hip-Hop Culture, and The Bilingual Review. Melissa is an active scholar in the fields of English literature, American Studies, African American Studies and Latin American/Latino Studies. At Yale, she focuses on the study of Afro-Latino history and culture in the 20th Century.

  14. Crowdsourcing, the great meteor storm of 1833, and the founding of meteor science.

    Science.gov (United States)

    Littmann, Mark; Suomela, Todd

    2014-06-01

    Yale science professor Denison Olmsted used crowdsourcing to gather observations from across the United States of the unexpected deluge of meteors on 13 November 1833--more than 72,000/h. He used these observations (and newspaper accounts and correspondence from scientists) to make a commendably accurate interpretation of the meteor storm, overturning 2100 years of erroneous teachings about shooting stars and establishing meteor science as a new branch of astronomy. Olmsted's success was substantially based on his use of newspapers and their practice of news pooling to solicit observations from throughout the country by lay and expert observers professionally unaffiliated with Yale College and him. In today's parlance, Olmsted was a remarkably successful early practitioner of scientific crowdsourcing, also known as citizen science. He may have been the first to use mass media for crowdsourcing in science. He pioneered many of the citizen-science crowdsourcing practices that are still in use today: an open call for citizen participation, a clearly defined task, a large geographical distribution for gathering data and a rapid response to opportunistic events. Olmsted's achievement is not just that he used crowdsourcing in 1833 but that crowdsourcing helped him to advance science significantly. Copyright © 2014 Elsevier Ltd. All rights reserved.

  15. Macitentan for the treatment of pulmonary arterial hypertension

    Directory of Open Access Journals (Sweden)

    Kholdani CA

    2014-11-01

    Full Text Available Cyrus A Kholdani,1 Wassim H Fares,2 Terence K Trow2 1Section of Pulmonary, Critical Care and Sleep Medicine, 2Yale Pulmonary Vascular Disease Program, Section of Pulmonary, Critical Care and Sleep Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, USA Abstract: Macitentan is the most recently approved dual endothelin-receptor antagonist (ERA for the treatment of symptomatic pulmonary arterial hypertension. Compared to other available ERAs, it demonstrates superior receptor-binding properties, with consequently improved tissue penetration, and a longer duration of action allowing for once-daily dosing. It has a favorable adverse-effect profile, with notably no demonstrable increase in the risk of hepatotoxicity or peripheral edema, but like other ERAs, it is potentially limited by significant anemia. Phase I data have demonstrated a favorable drug–drug interaction profile and no need for dose adjustment with hepatic and renal impairment. In the pivotal SERAPHIN study, treatment of symptomatic pulmonary arterial hypertension patients with macitentan led to statistically significant improvements in functional class, exercise tolerance, and hemodynamic parameters, in addition to a reduction in morbidity in an event-driven long-term trial. Keywords: endothelin, endothelin receptor antagonists, macitentan, pulmonary arterial hypertension

  16. Sensory phenomena related to tics, obsessive-compulsive symptoms, and global functioning in Tourette syndrome.

    Science.gov (United States)

    Kano, Yukiko; Matsuda, Natsumi; Nonaka, Maiko; Fujio, Miyuki; Kuwabara, Hitoshi; Kono, Toshiaki

    2015-10-01

    Sensory phenomena, including premonitory urges, are experienced by patients with Tourette syndrome (TS) and obsessive-compulsive disorder (OCD). The goal of the present study was to investigate such phenomena related to tics, obsessive-compulsive symptoms (OCS), and global functioning in Japanese patients with TS. Forty-one patients with TS were assessed using the University of São Paulo Sensory Phenomena Scale (USP-SPS), the Premonitory Urge for Tics Scale (PUTS), the Yale Global Tic Severity Scale (YGTSS), the Dimensional Yale-Brown Obsessive-Compulsive Scale (DY-BOCS), and the Global Assessment of Functioning (GAF) Scale. USP-SPS and PUTS total scores were significantly correlated with YGTSS total and vocal tics scores. Additionally, both sensory phenomena severity scores were significantly correlated with DY-BOCS total OCS scores. Of the six dimensional OCS scores, the USP-SPS scores were significantly correlated with measures of aggression and sexual/religious dimensions. Finally, the PUTS total scores were significantly and negatively correlated with GAF scores. By assessing premonitory urges and broader sensory phenomena, and by viewing OCS from a dimensional approach, this study provides significant insight into sensory phenomena related to tics, OCS, and global functioning in patients with TS. Copyright © 2015 Elsevier Inc. All rights reserved.

  17. Tourette syndrome and comorbid conditions: a spectrum of different severities and complexities.

    Science.gov (United States)

    Rizzo, Renata; Gulisano, Mariangela; Pellico, Alessandra; Calì, Paola Valeria; Curatolo, Paolo

    2014-10-01

    To investigate clinical correlates of Tourette syndrome and to identify the impact of comorbidities, we retrospectively recruited 92 young people affected by Tourette syndrome compared with 102 healthy controls. Neuropsychological assessment included: Youth Quality of Life-Research, Multidimensional Anxiety Scale for Children, Children's Depression Inventory, and Conner's and Child Behavior Checklist; moreover, Tourette syndrome patients completed the Yale Global Tic Severity Rating Scale and the Yale-Brown Obsessive Compulsive Scale. Four clinical subgroups were identified: pure Tourette syndrome (49.8%), Tourette syndrome plus attention-deficit hyperactivity disorder (ADHD) (22.2%), Tourette syndrome plus obsessive-compulsive disorder (21.5%), and Tourette syndrome plus ADHD plus obsessive-compulsive disorder (6.5%). Our findings suggested that emotional lability appeared in all Tourette syndrome subgroups, independently from comorbidities, representing a clinical feature of Tourette syndrome itself. Moreover, our data suggested that all 4 clinical subgroups had higher statistically significant behavioral problems compared with the healthy controls (P = .000), whereas affective and anxiety symptoms were overrepresented in Tourette syndrome plus comorbidities subgroups. Finally, Tourette syndrome patients had a lower quality of life compared with the healthy controls. These differences were statistically significant between the pure Tourette syndrome subgroups and Tourette syndrome plus comorbidities subgroups, as well as Tourette syndrome plus comorbidities subgroups and healthy controls. © The Author(s) 2014.

  18. My early days in photobiology with Philip Hanawalt

    International Nuclear Information System (INIS)

    Setlow, Richard B.

    2005-01-01

    Phil and I started our careers on somewhat similar scientific paths. I had an undergraduate degree in physics from Swarthmore College and a Ph.D. degree in physics from Yale for research in the field for ultraviolet spectroscopy. Phil received an undergraduate degree in Physics from Oberlin College, joined the Yale Physics Department in 1954, and transferred to the new Biophysics Department in 1955. We began our interactions then by virtue of the fact that Phil had to take a Laboratory Course in Experimental Physics, one part of which was spectroscopy in which I was the instructor. One of my principal interests was in the effects of different wavelengths of ultraviolet (UV) radiation on proteins, viruses and bacterial cells. So what was more natural than for Phil to dream up a Ph.D. research project to investigate the effects of different wavelengths of UV on macromolecular synthesis in Escherichia coli. I became his mentor with expertise in UV, whereas he did most of the microbiological/biochemical work. Thus began a collaboration and a communicating friendship, the latter going on for 50 years. That communication was essential in elucidating some of the important steps in nucleotide excision repair-a field in which Phil is a pre-eminent scholar and investigator

  19. Targeting cancers in the gastrointestinal tract: role of capecitabine

    Directory of Open Access Journals (Sweden)

    Muhammad Wasif Saif

    2009-03-01

    Full Text Available Muhammad Wasif SaifYale Cancer Center, Yale University School of Medicine, New Haven, CT, USAAbstract: Capecitabine is currently the only novel, orally home-administered fluorouracil prodrug. It offers patients more freedom from hospital visits and less inconvenience and complications associated with infusion devices. The drug has been extensively studied in large clinical trials in many solid tumors, including breast cancer, colorectal cancer, gastric cancer, and many others. Furthermore, the drug compares favorably with fluorouracil in patients with such cancers, with a safe toxicity profile, consisting mainly of gastrointestinal and dermatologic adverse effects. Whereas gastrointestinal events and hand-foot syndrome occur often with capecitabine, the tolerability profile is comparatively favorable. Prompt recognition of severe adverse effects is the key to successful management of capecitabine. Ongoing and future clinical trials will continue to examine, and likely expand, the role of capecitabine as a single agent and/or in combination with other anticancer agents for the treatment of gastrointestinal as well as other solid tumors, both in the advanced palliative and adjuvant settings. The author summarizes the current data on the role of capecitabine in the management of gastrointestinal cancers. Keywords: 5-fluorouracil, capecitabine, chemotherapy, adjuvant, advanced, colon cancer, gastric cancer, hepatocellular cancer, pancreatic cancer, cholangiocarcinoma, rectal cancer, anal cancer

  20. The Pace of Peace on the Viability of Bosnia and Herzegovina Twelve Years after Dayton

    Science.gov (United States)

    2007-06-01

    Martin van Creveld, “Before the State: Prehistory to AD 1300,” in The Rise and Decline of the State (Cambridge University Press, 1999), 1. 12 Yale H...4, no. 1 (March 2005): 58. 55 Kirsti Samuels and Vanessa Hawkins Wyeth, “State-Building and Constitutional Design after Conflict,” IPA Report...who benefit from violent conflict. Spoilers are intrinsically destabilizing. Edward Newman contends that “at the core of this broad definition are

  1. Effect of Contact Damage on the Strength of Ceramic Materials.

    Science.gov (United States)

    1982-10-01

    variables that are important to erosion, and a multivariate , linear regression analysis is used to fit the data to the dimensional analysis. The...of Equations 7 and 8 by a multivariable regression analysis (room tem- perature data) Exponent Regression Standard error Computed coefficient of...1980) 593. WEAVER, Proc. Brit. Ceram. Soc. 22 (1973) 125. 39. P. W. BRIDGMAN, "Dimensional Analaysis ", (Yale 18. R. W. RICE, S. W. FREIMAN and P. F

  2. Obsessive Compulsive Personality Disorder as a Predictor of Exposure and Ritual Prevention Outcome for Obsessive Compulsive Disorder

    OpenAIRE

    Pinto, Anthony; Liebowitz, Michael R.; Foa, Edna B.; Simpson, H. Blair

    2011-01-01

    Despite elevated rates of obsessive compulsive personality disorder (OCPD) in patients with obsessive compulsive disorder (OCD), no study has specifically examined comorbid OCPD as a predictor of exposure and ritual prevention (EX/RP) outcome. Participants were adult outpatients (n = 49) with primary OCD and a Yale-Brown Obsessive Compulsive Scale (YBOCS) total score ≥ 16 despite a therapeutic serotonin reuptake inhibitor dose for at least 12 weeks prior to entry. Participants received 17 ses...

  3. El Dr. Guillermo Contreras Da Silva, una figura señera en la microbiología y la salud pública chilena

    OpenAIRE

    Cabello,Felipe C

    2008-01-01

    The influence of the work of Dr. Guillermo Contreras Da Silva and his colaborators on the evolution of microbiology in Chile is briefly analyzed. Dr. Contreras was trained in modern virology at Yale University with Dr. J. Melnick under the sponsorhip of the Rockefeller Foundation. During this training, he used serological methods to classify Cocksakie viruses. After his return to Chile, he studied the epidemiology of enteroviruses, including poliovirus. His laboratory, the country's first in ...

  4. Extensible Open-Source Zero-Footprint Web Viewer for Oncologic Imaging Research | Informatics Technology for Cancer Research (ITCR)

    Science.gov (United States)

    The Tumor Imaging Metrics Core (TIMC), a CCSG Shared-Resource of the Dana-Farber/Harvard Cancer Center, has developed software for managing the workflow and image measurements for oncology clinical trials. This system currently is in use across the five Harvard hospitals to manage over 600 active clinical trials, with 800 users, and has been licensed and implemented at several other Cancer Centers, including Yale, Utah/Huntsman Cancer Institute, and UW/Seattle Cancer Care Alliance.

  5. Blatt v. Cabela's Retail, Inc. and a New Path for Transgender Rights

    OpenAIRE

    Levi, Jennifer; Barry, Kevin

    2018-01-01

    Published: Kevin Barry & Jennifer Levi, Blatt v. Cabela's Retail, Inc. and a New Path for Transgender Rights, 127 YALE L.J. F. 373 (2017). Since the Supreme Court recognized marriage equality in Obergefell v. Hodges, civil rights advocates have increasingly set their sights on transgender rights as the next legal frontier. Sex discrimination law, though an essential statutory tool, is not the only potential avenue for securing rights for transgender individuals. Another important federal ...

  6. [The fate of nuclides in natural water systems

    International Nuclear Information System (INIS)

    Turekian, K.K.

    1989-01-01

    Our research at Yale on the fate of nuclides in natural water systems has three components to it: the study of the atmospheric precipitation of radionuclides and other chemical species; the study of the behavior of natural radionuclides in groundwater and hydrothermal systems; and understanding the controls on the distribution of radionuclides and stable nuclides in the marine realm. In this section a review of our progress in each of these areas is presented

  7. Harnessing supramolecular peptide nanotechnology in biomedical applications

    OpenAIRE

    Chan, Kiat Hwa; Lee, Wei Hao; Zhuo, Shuangmu; Ni, Ming

    2017-01-01

    Kiat Hwa Chan,1 Wei Hao Lee,2 Shuangmu Zhuo,3 Ming Ni3 1Division of Science, Yale-NUS College, Singapore; 2Department of Chemistry, Krieger School of Arts & Sciences, Johns Hopkins University, Baltimore, MD, USA; 3Fujian Provincial Key Laboratory for Photonics Technology, Key Laboratory of OptoElectronic Science and Technology for Medicine of Ministry of Education, Fujian Normal University, Fuzhou, People’s Republic of China Abstract: The harnessing of peptides in biomedic...

  8. The Impact of Sustainability Information on Consumer Decision Making

    OpenAIRE

    O'Rourke, D; Ringer, A

    2016-01-01

    © 2015 by Yale University This article presents an empirical analysis of the impact of sustainability information on consumer purchase intentions and how this influence varies by issue (health, environment, and social responsibility), product category, type of consumer, and type of information. We assess over 40,000 online purchase interactions on the website GoodGuide.com and find a significant impact of certain types of sustainability information on purchase intentions, varying across diffe...

  9. Insourcing and Outsourcing for U.S. Department of Defense IT Projects: A Model

    Science.gov (United States)

    2011-01-01

    The New Element of Military Force Structure.” Parameters. 44.1 (2008): 72. Carey, Merrick “ Mac .” “The Political Setting for Defense Insourcing...AR2010021605762.html. OMB Communications. “ Big Savings Expected from Competitive Sourcing Initiative.” 2003-15 (May 29, 2003). http://www.whitehouse.gov...Haven and London: Yale University Press, 2009. Schumpeter. “Talent on Tap: The Fashion for Hiring Temps Has Reached the Executive Suite.” The Economist

  10. Confederate King of Battle: A Comparison of the Field Artillery Corps of the Army of Northern Virginia and the Army of Tennessee

    Science.gov (United States)

    2008-12-12

    1861 the flower of our educated youth gravitated toward the artillery.” Stiles graduated from Yale University and found the intellectual life in the...stubborn, aloof, insubordinate, quarrelsome, and childish .”3 Next in line was Gideon Pillow, Polk’s second in command. He and Polk feuded continually...generals, 57.5 percent, from Tennessee had similar experience. During 1862, all of the major generals in the Army of Northern Virginia had been educated

  11. Polygenic Scores for Major Depressive Disorder and Risk of Alcohol Dependence.

    Science.gov (United States)

    Andersen, Allan M; Pietrzak, Robert H; Kranzler, Henry R; Ma, Li; Zhou, Hang; Liu, Xiaoming; Kramer, John; Kuperman, Samuel; Edenberg, Howard J; Nurnberger, John I; Rice, John P; Tischfield, Jay A; Goate, Alison; Foroud, Tatiana M; Meyers, Jacquelyn L; Porjesz, Bernice; Dick, Danielle M; Hesselbrock, Victor; Boerwinkle, Eric; Southwick, Steven M; Krystal, John H; Weissman, Myrna M; Levinson, Douglas F; Potash, James B; Gelernter, Joel; Han, Shizhong

    2017-11-01

    Major depressive disorder (MDD) and alcohol dependence (AD) are heritable disorders with significant public health burdens, and they are frequently comorbid. Common genetic factors that influence the co-occurrence of MDD and AD have been sought in family, twin, and adoption studies, and results to date have been promising but inconclusive. To examine whether AD and MDD overlap genetically, using a polygenic score approach. Association analyses were conducted between MDD polygenic risk score (PRS) and AD case-control status in European ancestry samples from 4 independent genome-wide association study (GWAS) data sets: the Collaborative Study on the Genetics of Alcoholism (COGA); the Study of Addiction, Genetics, and Environment (SAGE); the Yale-Penn genetic study of substance dependence; and the National Health and Resilience in Veterans Study (NHRVS). Results from a meta-analysis of MDD (9240 patients with MDD and 9519 controls) from the Psychiatric Genomics Consortium were applied to calculate PRS at thresholds from P men; mean [SD] age, 38.2 [10.8] years) and 522 controls (151 [28.9.%] men; age [SD], 43.9 [11.6] years) from COGA; 631 cases (333 [52.8%] men; age [SD], 35.0 [7.7] years) and 756 controls (260 [34.4%] male; age [SD] 36.1 [7.7] years) from SAGE; 2135 cases (1375 [64.4%] men; age [SD], 39.4 [11.5] years) and 350 controls (126 [36.0%] men; age [SD], 43.5 [13.9] years) from Yale-Penn; and 317 cases (295 [93.1%] men; age [SD], 59.1 [13.1] years) and 1719 controls (1545 [89.9%] men; age [SD], 64.5 [13.3] years) from NHRVS. Higher MDD PRS was associated with a significantly increased risk of AD in all samples (COGA: best P = 1.7 × 10-6, R2 = 0.026; SAGE: best P = .001, R2 = 0.01; Yale-Penn: best P = .035, R2 = 0.0018; and NHRVS: best P = .004, R2 = 0.0074), with stronger evidence for association after meta-analysis of the 4 samples (best P = 3.3 × 10-9). In analyses adjusted for MDD status in 3 AD GWAS data

  12. Predictors of mortality within prison and after release among persons living with HIV in Indonesia

    Directory of Open Access Journals (Sweden)

    Culbert GJ

    2017-03-01

    Full Text Available Gabriel J Culbert,1,2 Forrest W Crawford,3–5 Astia Murni,6 Agung Waluyo,2 Alexander R Bazazi,7,8 Junaiti Sahar,2 Frederick L Altice7–9 1Department of Health Systems Science, College of Nursing, University of Illinois at Chicago, Chicago, IL, USA; 2Center for HIV/AIDS Nursing Research, Faculty of Nursing, Universitas Indonesia, Depok, Indonesia; 3Department of Biostatistics, Yale School of Public Health, 4Operations, Yale School of Management, 5Department of Ecology and Evolutionary Biology, Yale University, New Haven, CT, USA; 6Directorate General of Corrections, Indonesian Ministry of Law and Human Rights, Jakarta, Indonesia; 7Department of Epidemiology of Microbial Diseases, School of Public Health, 8Department of Medicine, Section of Infectious Diseases, AIDS Program, School of Medicine, Yale University, New Haven, CT, USA; 9Centre of Excellence for Research in AIDS (CERiA, University of Malaya, Kuala Lumpur, Malaysia Objectives: HIV-related mortality is increasing in Indonesia, where prisons house many people living with HIV and addiction. We examined all-cause mortality in HIV-infected Indonesian prisoners within prison and up to 24 months postrelease. Materials and methods: Randomly selected HIV-infected male prisoners (n=102 from two prisons in Jakarta, Indonesia, completed surveys in prison and were followed up for 2 years (until study completion or until they died or were lost to follow-up. Death dates were determined from medical records and interviews with immediate family members. Kaplan–Meier and Cox proportional hazards regression models were analyzed to identify mortality predictors. Results: During 103 person-years (PYs of follow-up, 15 deaths occurred, including ten in prison. The crude mortality rate within prison (125.2 deaths per 1,000 PYs was surpassed by the crude mortality rate (215.7 deaths per 1,000 PYs in released prisoners. HIV-associated opportunistic infections were the most common probable cause of death

  13. Laboratory and numerical simulation of internal wave attractors and their instability.

    Science.gov (United States)

    Brouzet, Christophe; Dauxois, Thierry; Ermanyuk, Evgeny; Joubaud, Sylvain; Sibgatullin, Ilias

    2015-04-01

    .-P. A., Geometric focusing of internal waves. J. Fluid Mech, 1995,. 300, 1-41 L. R. M. Maas, D. Benielli, J. Sommeria, and F.-P. A. Lam, Nature (London) 388, 557 (1997). 2. Dauxois, Thierry; Young, W., Journal of Fluid Mechanics, 1999, vol. 390, Issue 01, p.271-295 3. Grisouard, N., Staquet, C., Pairaud, I., 2008, Journal of Fluid Mechanics, 614, 1 4. Scolan, H., Ermanyuk, E., Dauxois, T., 2013, Physical Review Letters, 110, 234501 5. Mercier, Matthieu J.; Garnier, Nicolas B.; Dauxois, Thierry Reflection and diffraction of internal waves analyzed with the Hilbert transform Physics of Fluids, Volume 20, Issue 8, pp. 086601-086601-10 (2008).

  14. Progress in the domain of emissions tracking and environment radioactivity monitoring - Proceedings of the technical days organised by the SFRP Environment Section

    International Nuclear Information System (INIS)

    Calmet, Dominique; Calvez, Marianne; Rivasseau, Corinne Cea; Monfort, Marguerite; Manificat, Guillaume; Pierrard, Olivier; Couvez, Celine; Masson, Olivier; Bruno, Valerie; Renaud, Philippe; Genova, Zhana; Reynal, Nathalie; Le Coz, Eric; Tchilian, Nathalie; Diana, Jean-Jacques; Beguinel, Philippe; Cortes, Pierre; Puydarrieux, Stephane; Brun, Thierry; Devin, Patrick; Clavel, Benoit; Hemidy, Pierre-Yves; Gontier, Gilles; Delloye, Thierry; Mailliat, Alain; Ferreri, Giovanni; LECLERC, Elisabeth

    2015-11-01

    The Environment Section of the French Society of Radiation Protection (SFRP) organized a technical meeting on the progress made in the domain of emissions tracking and environment radioactivity monitoring. This document brings together the abstracts and the presentations (slides) of the different talks given at the meeting: 1 - Environment monitoring at the global, national and local scale: historical overview (Dominique CALMET, CEA); 2 - Evolution of radioactivity monitoring in the environment from 1960 to the present day (Guillaume MANIFICAT, IRSN); 3 - Euratom's legal framework (Zhana GENOVA, CTE); 4 - Main regulatory changes during the last decade (Nathalie REYNAL, ASN); 5 - Progress of standardization works on radioactive effluent emissions control and environment monitoring (Philippe BEGUINEL, BNEN); 6 - From operators' self-monitoring to ASN's inspections: a many components control system (Eric LE COZ, ASN); 7 - Control of effluents and emissions management at CEA Centres (Marianne CALVEZ, CEA); 8 - Liquid and gaseous effluents of ITER experimental facility: description and impacts (Pierre CORTES, IO); 9 - Effluents and emissions management strategy at AREVA NC La Hague facility (Stephane PUYDARRIEUX, AREVA); 10 - Radioactive effluents from nuclear facilities ongoing deconstruction: from dimensioning to real effluents (Benoit CLAVEL, EDF); 11 - Radionuclides decontamination process for liquid effluents using micro-algae at the laboratory scale (Corinne RIVASSEAU, CEA); 12 - Radioactive effluents from nuclear medicine services: management, monitoring and impact measurement methods (Nathalie TCHILIAN, ASN); 13 - Evolution history of effluents management and environment monitoring at the Solvay La Rochelle site (Thierry DELLOYE, SOLVAY); 14 - Different international approaches in effluents management and monitoring: example of French and German gaseous effluents - regulation, analyses, accounting rules (Jean-Jacques DIANA, ASN); 15 - Environment

  15. Identification of Emergency Department Visits in Medicare Administrative Claims: Approaches and Implications

    Science.gov (United States)

    Venkatesh, Arjun K.; Mei, Hao; Kocher, Keith E.; Granovsky, Michael; Obermeyer, Ziad; Spatz, Erica S.; Rothenberg, Craig; Krumholz, Harlan M.; Lin, Zhenqui

    2018-01-01

    Objectives Administrative claims data sets are often used for emergency care research and policy investigations of healthcare resource utilization, acute care practices, and evaluation of quality improvement interventions. Despite the high profile of emergency department (ED) visits in analyses using administrative claims, little work has evaluated the degree to which existing definitions based on claims data accurately captures conventionally defined hospital-based ED services. We sought to construct an operational definition for ED visitation using a comprehensive Medicare data set and to compare this definition to existing operational definitions used by researchers and policymakers. Methods We examined four operational definitions of an ED visit commonly used by researchers and policymakers using a 20% sample of the 2012 Medicare Chronic Condition Warehouse (CCW) data set. The CCW data set included all Part A (hospital) and Part B (hospital outpatient, physician) claims for a nationally representative sample of continuously enrolled Medicare fee-for-services beneficiaries. Three definitions were based on published research or existing quality metrics including: 1) provider claims–based definition, 2) facility claims–based definition, and 3) CMS Research Data Assistance Center (ResDAC) definition. In addition, we developed a fourth operational definition (Yale definition) that sought to incorporate additional coding rules for identifying ED visits. We report levels of agreement and disagreement among the four definitions. Results Of 10,717,786 beneficiaries included in the sample data set, 22% had evidence of ED use during the study year under any of the ED visit definitions. The definition using provider claims identified a total of 4,199,148 ED visits, the facility definition 4,795,057 visits, the ResDAC definition 5,278,980 ED visits, and the Yale definition 5,192,235 ED visits. The Yale definition identified a statistically different (p services in the

  16. Aliza Shvarts’s Art of Aborting: Queer Conceptions and Resistance to Reproductive Futurism

    Directory of Open Access Journals (Sweden)

    Ana Grahovac

    2013-07-01

    Full Text Available In April 2008, the Yale Daily News published an article introducing Yale University fine arts student Aliza Shvarts's senior undergraduate art project. In the article, Shvarts announced that as part of her project she had been privately artificially inseminating herself every month during a nine-month period, and performing self-induced miscarriages by ingesting abortifacient drugs each month. The announcement ignited a national controversy, sparking university protests and 'pro-life' outcries across internet communities. Ultimately, the Yale School of Art banned the project from being exhibited. No feminist made an immediate defence of Shvarts's work. Through an in-depth exploration of Shvarts's art project, this essay aims to critically interrogate the politics of reproduction and the rhetoric of futurity in relation to a woman's social and symbolic positioning in a culture that places heterosexual reproduction and the institution of family at the heart of future. I argue that Shvarts's project was an attempt to explore how art could be a means to empty the realm of femininity of its symbolic 'function' within a patriarchal order. By means of her radical refusal of reproduction, manifested in a series of repeated abortions, she staged a resistance to the patriarchal symbolic positioning of a woman – the positioning within which a woman's life is intelligible insofar as it follows the pre-determined reproductive narrative of 'natural' womanhood (birth, marriage, motherhood and death – so that a multitude of new narratives and possibilities could be birthed. I argue that Shvarts is the author of the possibility for imagining the future that is not mapped in advance for a woman – the future in which she is not an 'object' of reproduction but an 'author'. Drawing on Jack J. Halberstam's concept of 'shadow feminism' and Lee Edelman's 'reproductive futurism', I will also suggest that Shvarts's performance provides an invaluable reflection

  17. Scalable Spin-Qubit Circuits with Quantum Dots

    Science.gov (United States)

    2006-12-31

    Anisotropic Heisenberg Spin Rings” cond-mat/0608642. 13. Karyn Le Hur (Yale), Pascal Simon, and Daniel Loss, “Transport through a quantum dot with SU(4...Daniel Loss, “Nuclear spin state narrowing via gate--controlled Rabi oscillations in a double quantum dot” Phys. Rev. B 73, 205302 (2006). 27. Jörg...single spin read out (Delft), sqrt-of-swap (Harvard) and single spin Rabi oscillations. At the end of this program and based on our theoretical

  18. Aaron Temkin Beck (born July 18, 1921-) Biography

    OpenAIRE

    K. Fatih Yavuz; M. Hakan Türkçapar

    2012-01-01

    Aaron Beck was born in Providence, Rhode Island, USA, the youngest child of four siblings. Beck attended Brown University, graduating magna cum laude in 1942. Then he attended Yale Medical School, graduating with an M.D. in 1946. After his graduation, he served a rotating internship, followed by a residency in pathology at the Rhode Island Hospital. Although initially not interested in psychiatry, a residency in neurology at the Cushing Veterans Administration Hospital in Framingham, MA, requ...

  19. Differences in Dietary Preferences, Personality and Mental Health in Australian Adults with and without Food Addiction

    OpenAIRE

    Tracy Burrows; Leanne Hides; Robyn Brown; Christopher V Dayas; Frances Kay-Lambkin

    2017-01-01

    Increased obesity rates, an evolving food supply and the overconsumption of energy dense foods has led to an increase in research exploring addictive eating behaviours. This study aimed to investigate food addiction in a sample of Australian adults using the revised Yale Food Addiction Survey (YFAS) 2.0 tool and how it is associated with dietary intake, personality traits and mental health issues. Australian adults were invited to complete an online survey that collected information including...

  20. Imaginal desensitisation plus motivational interviewing for pathological gambling: randomised controlled trial.

    Science.gov (United States)

    Grant, Jon E; Donahue, Christopher B; Odlaug, Brian L; Kim, Suck Won; Miller, Michael J; Petry, Nancy M

    2009-09-01

    Sixty-eight individuals were randomised to either six sessions of imaginal desensitisation plus motivational interviewing (IDMI) or Gamblers Anonymous. Individuals assigned to IDMI had significantly greater reductions in Yale-Brown Obsessive Compulsive Scale Modified for Pathological Gambling total scores, gambling urges and gambling behaviour. People who failed to respond to Gamblers Anonymous reported significantly greater reduction in pathological gambling symptoms following later assignment to IDMI. Abstinence was achieved by 63.6% during the acute IDMI treatment period.

  1. Pathogenesis of Dengue Vaccine Viruses in Mosquitoes.

    Science.gov (United States)

    1980-01-01

    1973). Sabin (1948) showed that attenuated dpngiie, passed through mosquitoes, did not revert to pathogenicity frnr man. -7- Thus even if the vaccine ...AD-A138 518 PATHOGENESIS OF DENGUE VACCINE YIRUSES IN MOSQUITOES 1/ (U) YALE UNIV NEW HAVEN CONN SCHOOL OF MEDICINE B J BEATY ET AL. 9i JAN 80 DRND7...34 ’ UNCLASSIFIED 0{) AD 0Pathogenesis of dengue vaccine viruses in mosquitoes -First Annual Report Barry I. Beaty, Ph.D. Thomas H. G

  2. Governance, agricultural intensification, and land sparing in tropical South America

    OpenAIRE

    CEDDIA Michele Graziano; BARDSLEY N. O.; GOMEZ Y PALOMA Sergio; SEDLACEK S

    2014-01-01

    In this paper we address two topical questions: How do the quality of governance and agricultural intensification impact on spatial expansion of agriculture? Which aspects of governance are more likely to ensure that agricultural intensification allows sparing land for nature? Using data from the Food and Agriculture Organization, the World Bank, the World Database on Protected Areas, and the Yale Center for Environmental Law and Policy, we estimate a panel data model for six South A...

  3. Two Books on the Victorian Interest in Hellenism

    OpenAIRE

    Ogino, Masaru

    1997-01-01

    In the 1980s there appeared two books about the Victorian attitude towards the ancient Greeks, or about how the Victorians felt about incorporated the ancient Greek culture. The two books are Richard Jenkyn, The Victorians and Ancient Greece (Massachusetts: Harvard University Press, 1980) and Frank M. Turner, The Greek Heritage in Victorian Britain (New Haven: Yale University Press, 1984). Although they deal with the same subject, their approaches toward the subject are quite different from ...

  4. Canaletto's Colour: the inspiration and implications of changing grounds, pigments and paint application in the artist's English period

    Directory of Open Access Journals (Sweden)

    Roxane Sperber

    2016-04-01

    Full Text Available This article explores the English period of Giovanni Antonio Canal (Canaletto from a technical perspective. Six paintings by the artist, from the collection of the Yale Center for British Art, compose the focus of the study. Addressing the question of whether Canaletto’s English paintings were different or, as has long been held, inferior to his Venetian works, this article details changes to the artist’s grounds, painting technique, and palette when working in England.

  5. Equilibria of a Two-Person Non-Zerosum Noisy Game of Timing,

    Science.gov (United States)

    1981-01-01

    AD-A097 158 YALE UNIV NEW HAVEN CT COWLES FOUNDATION FOR RESEARC -ETC F/B 12/1 EQUILIBRIA OF A TWO-PERSON ON-ZEROSUN OISY GAME OF TIMING, CUb .JAN al...pubUo zeleale Distribution Unlimited. 1. Introduction Two toothpaste manufacturers are competing for a larger share of the dentifrice market . Each is...successfully capturing a share of the market , if its product hits the stores first. (This is assuming that the toothpaste is being technologically

  6. Popular music as an anticipation, “framing” and construction of generational memory of the 1968 students’ protest in Yugoslavia

    OpenAIRE

    Vasiljević Maja

    2013-01-01

    By focusing on the role of music within a certain political event - in this case, the students’ protests in Yugoslavia in June 1968 - I connect the sociology of music with the sociology of social movements as defined by American writers Ron Eyerman and Andrew Jamison. Moreover, I suggest further research based on the sociology of generations. I insist on the cultural basis of social movements, as argued by these Yale-educated sociologists. Contrary to the t...

  7. Eating Disorders in Obsessive-Compulsive Disorder: Prevalence and Effect on Treatment Outcome

    OpenAIRE

    Tobiassen, Linn Graham

    2013-01-01

    The aim of the present study was to examine the prevalence of eating disorder symptoms in patients with obsessive-compulsive disorder (OCD). Additional aims were to assess whether having comorbid eating disorders could influence the treatment outcome for OCD, and if symptoms of eating disorders were reduced after treatment for OCD. The sample consisted of 93 patients with a primary diagnosis of OCD. The patients underwent assessment with the Yale-Brown Obsessive-Compulsive Scale, Beck Depress...

  8. Tic Exacerbation in Adults with Tourette Syndrome: A Case Series

    OpenAIRE

    Sara M. Schaefer; Christopher A. Chow; Elan D. Louis; Daphne Robakis

    2017-01-01

    Background: Tourette syndrome (TS) has been described as peaking in adolescence with subsequent regression. We report patients who were diagnosed with TS during childhood who experienced a latent period (significant reduction in or absence of tics) followed by tic re-emergence in adulthood.Methods: We performed a retrospective chart review of outpatients over age 21 seen at the Yale neurology clinic between January 2012 and July 2016 who were diagnosed with childhood-onset tics, and...

  9. Basic training in mathematics a fitness program for science students

    CERN Document Server

    Shankar, R

    1995-01-01

    Based on course material used by the author at Yale University, this practical text addresses the widening gap found between the mathematics required for upper-level courses in the physical sciences and the knowledge of incoming students This superb book offers students an excellent opportunity to strengthen their mathematical skills by solving various problems in differential calculus By covering material in its simplest form, students can look forward to a smooth entry into any course in the physical sciences

  10. Industry is Not the Dark Side, but an Essential Partner to Make Progress in Reproductive Health

    OpenAIRE

    D'Hooghe, Thomas

    2016-01-01

    For the last 20 years, Thomas D'Hooghe has been coordinator of the Leuven University Fertility Center at Leuven University Hospitals, Belgium, one of the largest teaching hospitals in Europe. Since 1995, he has also been Professor of Reproductive Medicine and Biology at KU Leuven (University of Leuven) and Adjunct Professor at Yale University, USA. Since 1 October 2015, he has been the Vice President and Head of Global Medical Affairs Fertility at Merck's headquarters in Darmstadt, Germany. H...

  11. Main sequence of the metal-poor globular cluster M30 (NGC 7099)

    International Nuclear Information System (INIS)

    Alcaino, G.; Liller, W.

    1980-01-01

    We present photographic photometry for 673 stars in the metal-poor globular cluster M30 (NGC 7099). The Racine wedge was used with the CTIO 1-m Yale telescope (Δm=3/sup m/.60), the CTIO 4-m telescope (Δm=6/sup m/.83), and the ESO 3.6-m telescope (Δm=4/sup m/.12) to extend the photoelectric limit from Vapprox. =16.3 to Vapprox. =20.4. For the main-sequence turn-off, we have determined its position to lie at V=18.4 +- 0.1 (m.e.) and B-V=0.49 +- 0.03 (m.e.). From these values, we calculate the intrinsic values M/sub v/ =3.87 and (B-V) 0 =0.47. For the cluster as a whole, we derive a distance modulus (m-M)/sub V/=14.53 +- 0.15 and reddening E(B-V)=0.02 +- 0.02. Using the models of Iben and Rood [Astrophys. J. 159, 605 (1970)] and the isochrones of Demarque and McClure [(1977), in Evolution of Galaxies and Stellar Populations, edited by B. Tinsley and R. B. Larson (Yale University Observatory, New Haven), p. 199], we deduce the cluster's age to be 14.5( +- 4.0) x 10 9 yr. The large uncertainty in this value emphasizes the dire need for more work on cluster evolution

  12. Studying Acute Coronary Syndrome Through the World Wide Web: Experiences and Lessons.

    Science.gov (United States)

    Alonzo, Angelo A

    2017-10-13

    This study details my viewpoint on the experiences, lessons, and assessments of conducting a national study on care-seeking behavior for heart attack in the United States utilizing the World Wide Web. The Yale Heart Study (YHS) was funded by the National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health (NIH). Grounded on two prior studies, the YHS combined a Web-based interview survey instrument; ads placed on the Internet; flyers and posters in public libraries, senior centers, and rehabilitation centers; information on chat rooms; a viral marketing strategy; and print ads to attract potential participants to share their heart attack experiences. Along the way, the grant was transferred from Ohio State University (OSU) to Yale University, and significant administrative, information technology, and personnel challenges ensued that materially delayed the study's execution. Overall, the use of the Internet to collect data on care-seeking behavior is very time consuming and emergent. The cost of using the Web was approximately 31% less expensive than that of face-to-face interviews. However, the quality of the data may have suffered because of the absence of some data compared with interviewing participants. Yet the representativeness of the 1154 usable surveys appears good, with the exception of a dearth of African American participants. ©Angelo A Alonzo. Originally published in JMIR Research Protocols (http://www.researchprotocols.org), 13.10.2017.

  13. Supervised orthogonal discriminant subspace projects learning for face recognition.

    Science.gov (United States)

    Chen, Yu; Xu, Xiao-Hong

    2014-02-01

    In this paper, a new linear dimension reduction method called supervised orthogonal discriminant subspace projection (SODSP) is proposed, which addresses high-dimensionality of data and the small sample size problem. More specifically, given a set of data points in the ambient space, a novel weight matrix that describes the relationship between the data points is first built. And in order to model the manifold structure, the class information is incorporated into the weight matrix. Based on the novel weight matrix, the local scatter matrix as well as non-local scatter matrix is defined such that the neighborhood structure can be preserved. In order to enhance the recognition ability, we impose an orthogonal constraint into a graph-based maximum margin analysis, seeking to find a projection that maximizes the difference, rather than the ratio between the non-local scatter and the local scatter. In this way, SODSP naturally avoids the singularity problem. Further, we develop an efficient and stable algorithm for implementing SODSP, especially, on high-dimensional data set. Moreover, the theoretical analysis shows that LPP is a special instance of SODSP by imposing some constraints. Experiments on the ORL, Yale, Extended Yale face database B and FERET face database are performed to test and evaluate the proposed algorithm. The results demonstrate the effectiveness of SODSP. Copyright © 2013 Elsevier Ltd. All rights reserved.

  14. Laboratory and Modeling Studies of Insect Swarms

    Science.gov (United States)

    2016-03-10

    community of physicists and applied mathematicians working on so-called active materials. Following some of their work, we were thus motived to ask a...SUBJECT TERMS b. ABSTRACT 2. REPORT TYPE 17. LIMITATION OF ABSTRACT 15. NUMBER OF PAGES 5d. PROJECT NUMBER 5e. TASK NUMBER 5f. WORK UNIT NUMBER 5c...control number. PLEASE DO NOT RETURN YOUR FORM TO THE ABOVE ADDRESS. Yale University Office of Sponsored Projects 25 Science Park - 3rd Floor New Haven

  15. O desenvolvimento dos "Diagnosis Related Groups"- DRGs. Metodologia de classificação de pacientes hospitalares

    OpenAIRE

    Noronha,Marina F.; Veras,Cláudia T.; Leite,Iuri C.; Martins,Monica S.; Braga Neto,Francisco; Silver,Lynn

    1991-01-01

    É descrito o processo de desenvolvimento do sistema de classificação de pacientes internados em hospitais que atendem casos agudos, denominada Diagnosis Relatd Group - DRGs, desenvolvido e difundido por pesquisadores da Universidade de Yale, USA. Esse sistema vem a ser um instrumento que permite a mensuração do produto hospitalar, principalmente sob o ponto de vista gerencial. São apresentadas considerações acerca do que é entendido como produto hospitalar, seguindo nos meandros do desenvolvi...

  16. The development of "Diagnosis Related Groups" - DRGs, a methodology for classifying hospital patients

    OpenAIRE

    Noronha, Marina F.; Veras, Cláudia T.; Leite, Iuri C.; Martins, Monica S.; Braga Neto, Francisco; Silver, Lynn

    1991-01-01

    É descrito o processo de desenvolvimento do sistema de classificação de pacientes internados em hospitais que atendem casos agudos, denominada Diagnosis Relatd Group - DRGs, desenvolvido e difundido por pesquisadores da Universidade de Yale, USA. Esse sistema vem a ser um instrumento que permite a mensuração do produto hospitalar, principalmente sob o ponto de vista gerencial. São apresentadas considerações acerca do que é entendido como produto hospitalar, seguindo nos meandros do desenvolvi...

  17. Naval Station Guantanamo Bay: History and Legal Issues Regarding Its Lease Agreements

    Science.gov (United States)

    2016-11-17

    Jennifer K. Elsea. 4 Information on the Office of Military Commissions may be found online at http://www.mc.mil/ABOUTUS.aspx. Naval Station Guantanamo...abrogated and replaced with a new friendship treaty, the 1934 Treaty of Relations. 10 The Senate gave its advice and consent without condition on May 31... online at http://avalon.law.yale.edu/20th_century/dip_cuba002.asp. 8 U.S.-Cuba Treaty, 33 Stat. 2248. Ratifications were exchanged in July 1904. 9

  18. Short-range correlations with pseudopotentials

    International Nuclear Information System (INIS)

    Osman, A.

    1976-01-01

    Short-range correlations in nuclei are considered on an unitary-model operator approach. Short-range pseudopotentials have been added to achieve healing in the correlated wave functions. With the introduction of the pseudopotentials, correlated basis wave functions are constructed. The matrix element for effective interaction in nuclei is developed. The required pseudopotentials have been calculated for the Hamda-Johnston, Yale and Reid potentials and for the nuclear nucleon-nucleon potential A calculated by us according to meson exchange between nucleons. (Osman, A.)

  19. Light for the islands; Licht fuer die Inseln

    Energy Technology Data Exchange (ETDEWEB)

    Levitin, Michael; Krause, Matthias B.

    2010-10-15

    Electric power from solar cells makes the life of Panama's indigenous populations easier and helps them to hold on to their traditions. Electric lighting helps children to learn longer hours; women have more time for their traditional sewing work and can sell more; medical clinics now have refrigerators, and families save money they would otherwise have spent on kerosene. Hundreds of solar modules have already been installed in the Kuna Yale region; they improve life without affecting the indigenous culture. (orig.)

  20. Conference on renewable energies integration to power grids

    International Nuclear Information System (INIS)

    Laffaille, Didier; Bischoff, Torsten; Merkel, Marcus; Rohrig, Kurt; Glatigny, Alain; Quitmann, Eckard; Lehec, Guillaume; Teirlynck, Thierry; Stahl, Oliver

    2014-01-01

    The French-German office for Renewable energies (OFAEnR) organised a conference on renewable energies integration to power grids. In the framework of this French-German exchange of experience, more than 150 participants exchanged views on the perspectives and possible solutions of this integration in order to warrant the security of supplies and the grid stability in a context of increasing injection and decentralization of renewable power sources. This document brings together the available presentations (slides) made during this event: 1 - French distribution grids - Overview and perspectives (Didier Laffaille); 2 - Distribution Grids in Germany - Overview and Perspective (Torsten Bischoff); 3 - Integration of renewable energies into distribution grids - a case example from Germany (Marcus Merkel); 4 - Regeneratives Kombikraftwerk Deutschland: System Services with 100 % Renewable energies (Kurt Rohrig); 5 - Overview of the different grid instrumentation-control and automation tools (Alain Glatigny); 6 - Which Ancillary Services needs the Power System? The contribution from Wind Power Plants (Eckard Quitmann); 7 - The Flexibility Aggregator - the example of the GreenLys Project (Guillaume Lehec); 8 - Energy Pool - Providing flexibility to the electric system. Consumption cut-off solutions in France (Thierry Teirlynck); 9 - Demand Response experiences from Germany (Oliver Stahl)

  1. Yachting Club

    CERN Multimedia

    Yachting Club

    2011-01-01

    Club life - and solo sailing We tend to forget that ResQ, our trusty Surveillance boat, is as much a part of Club life as those mere unmotored boats everyone is so keen on, so here is a nice picture of ResQ in action taken by Makiko Takayama during the most recent Match Racing. The crew look a bit cold and windswept despite August sun, so all our thanks for doing a necessary - but always fun - job. We have recruited several new Q-boat skippers this season but more are needed: it is no secret that we periodically have difficulty in manning her 5 - 6 times a week. If you have a Permis Moteur or aspire to it, please let the Committee know. Most sailors will know (and if not, you should be checking our website Blogs more often!) that YCC was represented in the Translémanique solo regatta this year as well as last year, by Thierry and Andrea respectively - both of whom did very well. Our website gives you links to their Blogs too. The question resulted however, how come they were allowed to sail a...

  2. Are uranium reserves adequate?

    International Nuclear Information System (INIS)

    Anon.

    2006-01-01

    Against a backdrop of growing concerns about global warming and geopolitical pressures on fossil energies, especially natural gas and oil, interest in nuclear power has revived considerably. Conscious of its addiction to oil and reeling from a series of gigantic blackouts, the United States, in the words of its president, must 'aggressively move forward with the construction of nuclear power plants'. Some European countries have approved new power plant construction (Finland and France), while the more reserved ones (Belgium, Germany and Sweden) have begun to show a change in attitude. Asia, meanwhile, is host to the planet's largest number of potential nuclear construction projects in this first half of the 21. century. All these signs point to a sharp rise in uranium consumption, the basic fuel for these plants. But are there enough resources to support a nuclear revival on a planetary scale? The publication of the Red Book on uranium in late May 2006 was an opportunity for Thierry Dujardin, Deputy Director of Science and Development at the OECD's Nuclear Energy Agency, to take stock of resources. He gives his opinion in this paper

  3. Yachting club

    CERN Multimedia

    Yachting club

    2011-01-01

    Regattas everywhere (bis)! A fornight ago, we reported on imminent Match-Racing of the Surprises as the highlight of the season: it has now happened of course, and been written up on the Website Blog - along with the results of the Semaine du Soir of Versoix, which happened a week later, with many YCC teams competing: it is nice to report that our dinghies (either club-owned or skippered) wiped up the opposition! Sanja’s photo herewith from the Bol d’Or implies that there were some Surprises (and others) actually ahead of our Mic Mac - truth be told, there were, at different stages, but the event June 18/19 was a good regatta, if a very hard one as the wind strengths were Bf 6 with Bf7 gusts. Sanja reports that this regatta was more impressive and much harder than the SdS: skipper Thierry, on Mic Mac, did a great job, from an excellent start which kept her among the first ten Surprises for 4 hours - not bad, when they finished the regatta after ~13 hours, with 26th position out of 109 Su...

  4. Análise Literária e Quadrinhística e transposição do Conto Assassinatos na Rua Morgue, de Edgar Allan Poe

    Directory of Open Access Journals (Sweden)

    Adriano Souza Freitas

    2018-02-01

    Full Text Available For some time, some national literary texts have been adapted to comics, In this same flow, scholars are looking to analyze how this practice is being performed. We followed similar paths, but from a foreign writer, Edgar Allan Poe. Thus, the aim of this work is not only to analyze the "adaptation" of the Murder story in Morgue Street, but also to perform a literary analysis of the story, as well as to make a comparison between the arts, without merit of valuation. For the accomplishment of this work, it had been used books of the literary seam of writers like Tzvetan Todorov and Massaud Moisés, as well as of writers who are dedicated to the study of the comic like Thierry Groensteen. The research was bibliographical, however, whenever necessary a comparative-historical subsidy was sought. From the readings and the writing of the text, the richness of the literary tale and its "adaptation", that is, of the HQ, was perceived. The idea is therefore that it is not necessary to prioritize the arts, because they are different and with objectives, in many cases different, but can be completed depending on the purpose.

  5. Conference on offshore wind energy in France and Germany: challenges of a promising segment

    International Nuclear Information System (INIS)

    Chrupek, Thierry; Falk, Thorsten; Hofmann, Stefanie; Gouverneur, Philippe; Le Visage, Christophe; Saint Martin, Gro de; Meyerjuergens, Tim; Dachicourt, Pierre-Georges; Hube, Wilfried

    2008-01-01

    The French-German office for Renewable energies (OFAEnR) organised a conference on the development of offshore wind energy in France and Germany. In the framework of this French-German exchange of experience, more than 100 participants exchanged views on offshore wind energy development, and on the conflicts of usage between fishermen and offshore wind farms. This document brings together the available presentations (slides) made during this event: 1 - Offshore wind energy development in France (Thierry Chrupek); 2 - Present day situation of offshore wind energy development and use in Germany (Thorsten Falk); 3 - Risks and profitability of offshore wind energy (Philippe Gouverneur); 4 - Sea and shore integrated management: what impacts for offshore wind energy? (Christophe Le Visage); 5 - Towards and offshore grid? (Gro de Saint Martin); 6 - Grid connection of offshore wind farms in Germany (Tim Meyerjuergens); 7 - Conflicts of usage between professional fishing and offshore wind farms (Pierre-Georges Dachicourt); 8 - Ecological evaluative research for the use of offshore wind energy - Advantages, projects and studies. Environmental follow-up of wind energy projects (Stefanie Hofmann); 9 - Alpha Ventus offshore test park: context, progress of the installation and next steps (Wilfried Hube)

  6. Global copy number profiling of cancer genomes | Office of Cancer Genomics

    Science.gov (United States)

    In this article, we introduce a robust and efficient strategy for deriving global and allele-specific copy number alternations (CNA) from cancer whole exome sequencing data based on Log R ratios and B-allele frequencies. Applying the approach to the analysis of over 200 skin cancer samples, we demonstrate its utility for discovering distinct CNA events and for deriving ancillary information such as tumor purity. Availability and implementation: https://github.com/xfwang/CLOSE CONTACT: xuefeng.wang@stonybrook.edu or michael.krauthammer@yale.edu. (Publication Abstract)

  7. The Near-IR TRGB Magnitude and Distance Modulus to NGC 185

    Directory of Open Access Journals (Sweden)

    Y.-J. Sohn

    2008-09-01

    Full Text Available We determined values of distance modulus to nearby dwarf galaxy NGC 185 from the Tip of Red-Giant Branch (TRGB method. Apparent magnitudes of the TRGB are estimated from the near-infrared JHK luminosity functions (LFs of the resolved giant branch stars. Theoretical absolute magnitudes of the TRGB in near-infrared bands have been extracted from the Yonsei-Yale isochrones. The observed apparent and theoretical absolute magnitudes of the TRGB provide values of distance modulus to NGC 185 as (m - M.

  8. Theoretical aspects of electroweak and other interactions in medium energy physics

    International Nuclear Information System (INIS)

    Mukhopadhyay, N.C.

    1992-01-01

    Progress in the study of electroweak structure of baryon resonances and in the analysis of data for pion and eta photoproduction. Four graduate students are currently associated with the program. One has obtained his Ph.D. degree in the year under review. Six research articles have been completed in this year, and five conference contributions have been made. Collaborations with scientists from Illinois, Los Alamos, Westinghouse, William and Mary, Yale, Mainz (Germany), Saskatchewan (Canada) and TRIUMF (Canada) continue, along with participation in collaborations at CEBAF

  9. Reading the Revolution: Where Has the Literature Taken Us in Understanding Cuba?

    Directory of Open Access Journals (Sweden)

    Antoni Kapcia

    2005-10-01

    Full Text Available – Cuba. A New History, by Richard Gott. New Haven and London: Yale University Press, 2004. – The Cuban Revolution. Past, Present and Future Perspectives, by Geraldine  Lievesley. Houndmills, Basingstoke: Palgrave Macmillan, 2004. – People’s Power. Cuba’s Experience with Representative Government, by Peter  Roman. (Updated edition Lanham, Boulder, New York, Toronto, Oxford:  Rowman & Littlefield Publishers Inc.  – Cuba. A Revolution in Motion, by Isaac Saney. Black Point, Nova Scotia: Fernwood Books; London: Zed Books, 2003.

  10. Approximate Cores of a General Class of Economies. Part II. Set-Up Costs and Firm Formation in Coalition Production Economies,

    Science.gov (United States)

    1982-02-01

    r AAI1Z 608 YALE UNIV NEW HAVEN CT C OWLES FOUNDATION FOR RESEARC --ETC F/G 513 APPROXIMATE CORES 6F A GENERAL CLASS OF ECONOMIES. PART It. SET--ETC(U...theoretic models of the economy in strategic form are institutional. Markets and firms and even money are assumed to exist. Cooperative game theory can be...groups. Alternatively we can define firms and firms- in-being, specify the manner of trade in the markets , define what is meant by entry and exit and

  11. A microwave inverse Cerenkov Accelerator (MICA)

    International Nuclear Information System (INIS)

    Hirshfield, Jay L.

    1999-01-01

    The objective of this Phase II SBIR research program was to complete the final design originated during Phase I for a prototype Microwave Inverse Cerenkov Accelerator (MICA), to fabricate the-prototype MICA, and to test its performance as an electron accelerator. This report contains details of the design, predictions of accelerator performance, results of cold tests on the MICA structure, and details of the installation of MICA on the Yale Beam Physics Laboratory 6-MeV beamline. Discussion of future work is also included

  12. Optical processes in microparticles and nanostructures

    CERN Document Server

    Poon, Andrew W

    2011-01-01

    This Festschrift is a tribute to the eminent scholar, Professor Richard Kounai Chang, on his retirement from Yale University on June 12, 2008. During his over four decades of scientific exploration, Professor Chang has made a lasting contribution to the development of linear and nonlinear optics and devices in confined geometries, of surface second-harmonic generation and surface-enhanced Roman scattering, and of novel methods for detecting airborne aerosol pathogens. This volume assembles a collection of articles contributed by former students, collaborators, and colleagues of Professor Chang

  13. Motives for eating tasty foods associated with binge-eating. Results from a student and a weight-loss seeking population☆

    OpenAIRE

    Boggiano, M.M.; Burgess, E.E.; Turan, B.; Soleymani, T.; Daniel, S.; Vinson, L.D.; Lokken, K.L.; Wingo, B.C.; Morse, A.

    2014-01-01

    The aim of this study was to use the Palatable Eating Motives Scale (PEMS) to determine if and what motives for eating tasty foods (e.g., junk food, fast food, and desserts) are associated with binge-eating in two diverse populations. BMI and scores on the PEMS, Yale Food Addiction Scale (YFAS), and Binge-eating Scale (BES) were obtained from 247 undergraduates at the University of Alabama at Birmingham (UAB) and 249 weight-loss seeking patients at the UAB EatRight program. Regression analyse...

  14. Dicty_cDB: Contig-U16583-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available ii voucher MHNG INVE29753 28S la... 396 0.0 18 ( EU272595 ) Tripedalia cystophora voucher persona...17 ( EU272576 ) Nanomia bijuga voucher Yale Peabody Museum No. 35... 396 0.0 18 ( EU272575 ) Melicertum octocostatum voucher persona...l:G. Macki... 396 0.0 17 ( EU272574 ) Lizzia blondina voucher persona...l:P. Schuchert:Sch... 396 0.0 17 ( EU272573 ) Leuckartiara octona voucher personal:P. Schuchert....likerina fasciculata voucher personal:P. Schu... 396 0.0 17 ( EU272570 ) Stomotoc

  15. Latent class analysis of the Yale-Brown Obsessive-Compulsive Scale symptoms in obsessive-compulsive disorder

    NARCIS (Netherlands)

    Delucchi, K.L.; Katerberg, H.; Stewart, S.E.; Denys, D.A.; Lochner, C.; Stack, D.E.; den Boer, J.A.; van Balkom, A.J.L.M.; Jenike, M.A.; Stein, D.J.; Cath, D.C.; Mathews, C.A.

    2011-01-01

    Objective: Obsessive-compulsive disorder (OCD) is phenomenologically heterogeneous, and findings of underlying structure classification based on symptom grouping have been ambiguous to date. Variable-centered approaches, primarily factor analysis, have been used to identify homogeneous groups of

  16. Clinical utility of vandetanib in the treatment of patients with advanced medullary thyroid cancer

    Directory of Open Access Journals (Sweden)

    Deshpande H

    2011-12-01

    Full Text Available Hari Deshpande1,3, Vicky Marler3, Julie Ann Sosa2,31Department of Medicine, 2Department of Surgery, Yale University School of Medicine, 3Yale Cancer Center, New Haven, CT, USAAbstract: Vandetanib (ZD6474 became the first systemic agent to be approved for the treatment of metastatic or locally advanced medullary thyroid cancer. It was a proof of principle, because it is an orally bioavailable medication that targets the growth factors felt to be important in the pathogenesis of this disease, ie, the rearranged during transfection proto-oncogene and vascular endothelial growth factor receptor. It was tested initially in two Phase II studies at doses of 100 mg and 300 mg daily. Although activity was seen at both doses, the higher dose was chosen for a randomized, placebo-controlled Phase II study. This trial, which accrued more than 300 patients, showed a statistically significant benefit for the group taking vandetanib compared with those taking placebo medication. Progression-free survival for the vandetanib arm has not been reached, compared with 19 months for the placebo arm. The main toxicity appears to be diarrhea, although some patients experienced significant side effects, including torsades de pointes and sudden cardiac death. Therefore, it is now necessary for practitioners to enroll in a Risk Evaluation Mitigation Strategy before being allowed to prescribe this medication, to reduce the risk of serious side effects occurring.Keywords: ZD6474, medullary thyroid cancer, vandetanib

  17. Exponential local discriminant embedding and its application to face recognition.

    Science.gov (United States)

    Dornaika, Fadi; Bosaghzadeh, Alireza

    2013-06-01

    Local discriminant embedding (LDE) has been recently proposed to overcome some limitations of the global linear discriminant analysis method. In the case of a small training data set, however, LDE cannot directly be applied to high-dimensional data. This case is the so-called small-sample-size (SSS) problem. The classical solution to this problem was applying dimensionality reduction on the raw data (e.g., using principal component analysis). In this paper, we introduce a novel discriminant technique called "exponential LDE" (ELDE). The proposed ELDE can be seen as an extension of LDE framework in two directions. First, the proposed framework overcomes the SSS problem without discarding the discriminant information that was contained in the null space of the locality preserving scatter matrices associated with LDE. Second, the proposed ELDE is equivalent to transforming original data into a new space by distance diffusion mapping (similar to kernel-based nonlinear mapping), and then, LDE is applied in such a new space. As a result of diffusion mapping, the margin between samples belonging to different classes is enlarged, which is helpful in improving classification accuracy. The experiments are conducted on five public face databases: Yale, Extended Yale, PF01, Pose, Illumination, and Expression (PIE), and Facial Recognition Technology (FERET). The results show that the performances of the proposed ELDE are better than those of LDE and many state-of-the-art discriminant analysis techniques.

  18. Pathological gambling: comorbid psychiatric diagnoses in patients and their families.

    Science.gov (United States)

    Dannon, Pinhas N; Lowengrub, Katherine; Aizer, Anat; Kotler, Moshe

    2006-01-01

    Pathological gambling is a highly prevalent and disabling impulse control disorder. Recent studies have consistently demonstrated that pathological gamblers respond well to treatment with selective serotonin reuptake inhibitors, mood stabilizers and opioid antagonists. These findings have supported the observation that pathological gambling is associated with anxiety and mood spectrum disorders as well as addictive disorders. Fifty-two male pathological gamblers and their first-degree relatives (n=93) completed a semi-structured DSM-IV-based diagnostic interview as well as a series of data collection instruments including the South Oaks Gambling Scale, the Hamilton Rating Scale for Depression, the Hamilton Rating Scale for Anxiety, the Yale-Brown Obsessive-Compulsive Scale, and the Young Mania Rating Scale. The study subjects and their first-degree relative were compared to demographically matched normal controls (n=96). We found higher prevalence of alcohol, substance abuse, problematic gambling, depression, and anxiety disorders in the pathological gamblers and their first-degree relatives than in the control group. In particular, the scores on the Hamilton Rating Scale for Depression, the Hamilton Rating Scale for Anxiety, and the Yale-Brown Obsessive-Compulsive Scale were higher in the study group than in the control group. Our finding of a high prevalence of psychiatric comorbidity in pathological gamblers and their families raises the question of the proper classification of pathological gambling in the DSM-IV. Furthermore, the pattern of psychiatric disorders seen in the first-degree relatives can lead to new insights about the etiopathology of pathological gambling.

  19. Randomized trial of behavior therapy for adults with Tourette syndrome.

    Science.gov (United States)

    Wilhelm, Sabine; Peterson, Alan L; Piacentini, John; Woods, Douglas W; Deckersbach, Thilo; Sukhodolsky, Denis G; Chang, Susanna; Liu, Haibei; Dziura, James; Walkup, John T; Scahill, Lawrence

    2012-08-01

    Tics in Tourette syndrome begin in childhood, peak in early adolescence, and often decrease by early adulthood. However, some adult patients continue to have impairing tics. Medications for tics are often effective but can cause adverse effects. Behavior therapy may offer an alternative but has not been examined in a large-scale controlled trial in adults. To test the efficacy of a comprehensive behavioral intervention for tics in adults with Tourette syndrome of at least moderate severity. A randomized controlled trial with posttreatment evaluations at 3 and 6 months for positive responders. Three outpatient research clinics. Patients (N = 122; 78 males; age range, 16-69 years) with Tourette syndrome or chronic tic disorder were recruited between December 27, 2005, and May 21, 2009. Patients received 8 sessions of comprehensive behavioral intervention for tics or 8 sessions of supportive treatment for 10 weeks. Patients with a positive response were given 3 monthly booster sessions. Total tic score on the Yale Global Tic Severity Scale and the Clinical Global Impression-Improvement scale rated by a clinician masked to treatment assignment. Behavior therapy was associated with a significantly greater mean (SD) decrease on the Yale Global Tic Severity Scale (24.0 [6.47] to 17.8 [7.32]) from baseline to end point compared with the control treatment (21.8 [6.59] to 19.3 [7.40]) (P Tourette syndrome. clinicaltrials.gov Identifier: NCT00231985.

  20. Peripheral laser iridoplasty opens angle in plateau iris by thinning the cross-sectional tissues

    Directory of Open Access Journals (Sweden)

    Liu J

    2013-09-01

    Full Text Available Ji Liu,1,2 Tania Lamba,1 David A Belyea1 1Department of Ophthalmology, The George Washington University, Washington DC, USA; 2Yale Eye Center, Yale University, New Haven, CT, USA Abstract: Plateau iris syndrome has been described as persistent angle narrowing or occlusion with intraocular pressure elevation after peripheral iridotomy due to the abnormal plateau iris configuration. Argon laser peripheral iridoplasty (ALPI is an effective adjunct procedure to treat plateau iris syndrome. Classic theory suggests that the laser causes the contraction of the far peripheral iris stroma, "pulls" the iris away from the angle, and relieves the iris-angle apposition. We report a case of plateau iris syndrome that was successfully treated with ALPI. Spectral domain optical coherence tomography confirmed the angle was open at areas with laser treatment but remained appositionally closed at untreated areas. Further analysis suggested significant cross-sectional thinning of the iris at laser-treated areas in comparison with untreated areas. The findings indicate that APLI opens the angle, not only by contracting the iris stroma, but also by thinning the iris tissue at the crowded angle. This is consistent with the ALPI technique to aim at the iris as far peripheral as possible. This case also suggests that spectral domain optical coherence tomography is a useful adjunct imaging tool to gonioscopy in assessing the angle condition. Keywords: plateau iris, optic coherence tomography, argon laser peripheral iridoplasty, angle-closure glaucoma

  1. Tic disorders and the premonitory urge.

    Science.gov (United States)

    Steinberg, Tamar; Shmuel Baruch, Sharona; Harush, Adva; Dar, Ruvi; Woods, Doug; Piacentini, John; Apter, Alan

    2010-02-01

    The aims of this study were to examine a non-English (Hebrew) version of a scale that measures the premonitory urge in children suffering from tic disorder, as well as examine the correlations of the urge with demographic and clinical aspects of Tourette Syndrome. Forty children and adolescents, suffering from tics participated in this study. They were assessed with the Premonitory Urge for Tics Scale (PUTS); the Yale Global Tic Severity Scale (YGTSS); the Childhood Version of the Yale Brown Obsessive Compulsive Scale (CYBOCS); the ADHD Rating Scale IV (Conners) Scale; the Screen for Child Anxiety Related Emotional Disorders (SCARED); and the Child Depression Inventory (CDI). The mean PUTS score was 20.15 (SD = 5.89). For the entire sample the PUTS was found to be internally consistent at a = 0.79. Youths older than 10 years had higher consistency (a = 0.83) than youths younger than 10 (a = 0.69). Premonitory urge was not correlated with tic severity in the entire sample. In youths older than 10, as opposed to youths younger than 10, premonitory urge did correlate with obsessions, compulsions and depression, but not with anxiety or with ADHD. The premonitory urge can be measured reliably and the PUTS is a useful instrument for measuring this important phenomena. Premonitory urges seems to be related to obsessions, compulsions, and depression in older children and this may have implications for the developmental psychopatholgy of these symptoms.

  2. Book Reviews

    Directory of Open Access Journals (Sweden)

    J.C. Anceaux

    1967-10-01

    Full Text Available - L. Sluimers, M.E. Osborne, Strategic hamlets in South Viet-nam. A survey and a comparison. Southeast Asia Program, Department of Asian Studies, Data Paper no. 55. Ithaca, Cornell University Press, 1965. XII, 66 blz., X, krt. - L. Sluimers, F.B. Weinstein, Vietnam’s unheld elections: The failure to carry out the 1956 reunification elections and the effect on Hanoi’s present outlook. Data Paper: No. 60, Southeast Asia Program. Department of Asian Studies. Cornell University. Ithaca, Cornell University Press, 1966. VII, 65 blz., XIII. - L. Sluimers, D.E. Weatherbee, Ideology in Indonesia: Sukarno’s Indonesian revolution. Monograph Series No. 8. Southeast Asia Studies, Yale University, 1966. X, 135 blz., VII. - J.H.A. Logemann, Donald E. Weatherbee, Ideology in Indonesia: Soekarno’s Indonesian Revolution. Southeast Asia Studies Monograph Series no. 8. Yale University, 1967. 135 pp., Charts, glossary. - H.J. de Graaf, A.B. Ward, Rajah’s servant. With a preface by Robert M. Pringle and Otto C. Doering III. Data Paper: No. 61. South East Asia Program. Department of Asian Studies. Cornell University, Ithaca, New York. Nov. 1966. - J.C. Anceaux, Viktor Krupa, Morpheme and word in Maori. (Janua Linguarum, Series Practica. XLVI. Mouton & Co., The Hague 1966. 83 pp. - G.D. van Wengen, Surinam. Grammofoonplaat, uitgave Philips. Serie: “Song and sound the World Around”. Stereo 831 231 PY (ook als mono speelbaar, 33 1/3 t.

  3. Neuraxial and peripheral nerve blocks in patients taking anticoagulant or thromboprophylactic drugs: challenges and solutions

    Directory of Open Access Journals (Sweden)

    Li J

    2015-08-01

    Full Text Available Jinlei Li, Thomas Halaszynski Department of Anesthesiology, Yale University, Yale New Haven Hospital, New Haven, CT, USA Abstract: Incidence of hemorrhagic complications from neuraxial blockade is unknown, but classically cited as 1 in 150,000 epidurals and 1 in 220,000 spinals. However, recent literature and epidemiologic data suggest that for certain patient populations the frequency is higher (1 in 3,000. Due to safety concerns of bleeding risk, guidelines and recommendations have been designed to reduce patient morbidity/mortality during regional anesthesia. Data from evidence-based reviews, clinical series and case reports, collaborative experience of experts, and pharmacology used in developing consensus statements are unable to address all patient comorbidities and are not able to guarantee specific outcomes. No laboratory model identifies patients at risk, and rarity of neuraxial hematoma defies prospective randomized study so “patient-specific” factors and “surgery-related” issues should be considered to improve patient-oriented outcomes. Details of advanced age, older females, trauma patients, spinal cord and vertebral column abnormalities, organ function compromise, presence of underlying coagulopathy, traumatic or difficult needle placement, as well as indwelling catheter(s during anticoagulation pose risks for significant bleeding. Therefore, balancing between thromboembolism, bleeding risk, and introduction of more potent antithrombotic medications in combination with regional anesthesia has resulted in a need for more than “consensus statements” to safely manage regional interventions during anticoagulant/thromboprophylactic therapy. Keywords: antithrombotics, novel oral anticoagulant, regional, neurologic dysfunction, hematoma, peripheral nerve blockade

  4. Psicopatología del trastorno obsesivo compulsivo

    OpenAIRE

    Albert Colomer, Carmen

    2011-01-01

    Se ha analizado a una población de 35 sujetos diagnosticados de trastorno obsesivo compulsivo (TOC) seleccionados durante un año de toda la población que consultó en un equipo de salud mental. En estos pacientes se analizó: 1. Las características de las obsesiones utilizando la escala de Yale-Brown para el trastorno obsesivo compulsivo. 2. Sintomatología acompañante y comorbilidad mediante la aplicación del sistema SCAN (cuestionario para la Evalluación Clínica en Neuropsiquiatría). 3. Discap...

  5. Report to users of ATLAS, December 1995

    International Nuclear Information System (INIS)

    Ahmad, I.; Glagola, B.

    1995-12-01

    This report covers the following: status of ATLAS accelerator; highlights of recent research at ATLAS; research related concept for an Advanced Exotic Beam Facility on ATLAS; program advisory committee; and ATLAS user group executive committee. Research highlights are given for the following: APEX progress report; transport efficiency of the Argonne Fragment Mass Analyzer; collective motion in light polonium isotopes; angular correlation measurements for 12 C(g.s.) + 12 C(3-,9.64MeV) inelastic scattering; and the AYE-ball (Argonne-Yale-European gamma spectrometer) used to study the structure of nuclei far from stability

  6. Changing the science education paradigm: from teaching facts to engaging the intellect: Science Education Colloquia Series, Spring 2011.

    Science.gov (United States)

    Fischer, Caleb Nathaniel

    2011-09-01

    Dr. Jo Handelsman, Howard Hughes Medical Institute Professor in the Department of Molecular, Cellular and Developmental Biology at Yale University, is a long-time devotee of scientific teaching, receiving this year's Presidential Award for Science Mentoring. She gave a seminar entitled "What is Scientific Teaching? The Changing Landscape of Science Education" as a part of the Scientific Education Colloquia Series in spring 2011. After dissecting what is wrong with the status quo of American scientific education, several ideological and practical changes are proposed, including active learning, regular assessment, diversity, and mentorship. Copyright © 2011.

  7. Is Contract Law Necessary?

    OpenAIRE

    SCHWARTZ, Alan

    2010-01-01

    This lecture was delivered on 17 March 2010. Alan Schwartz, Sterling Professor of Law; Professor of Management, Yale University This Lecture argues that much of the contract law in the cases (the US, the UK and Canada) and in the codes (Europe and Latin America) is unnecessary. To say that a law is unnecessary is to say that it does not perform a useful social function. The argument below thus sets out the functions that contract laws today are thought to serve, and then shows that many of...

  8. Lie algebras

    CERN Document Server

    Jacobson, Nathan

    1979-01-01

    Lie group theory, developed by M. Sophus Lie in the 19th century, ranks among the more important developments in modern mathematics. Lie algebras comprise a significant part of Lie group theory and are being actively studied today. This book, by Professor Nathan Jacobson of Yale, is the definitive treatment of the subject and can be used as a textbook for graduate courses.Chapter I introduces basic concepts that are necessary for an understanding of structure theory, while the following three chapters present the theory itself: solvable and nilpotent Lie algebras, Carlan's criterion and its

  9. Implications of the 14C(α,γ)18O reaction for nonstandard big bang nucleosynthesis

    International Nuclear Information System (INIS)

    Gai, M.

    1992-01-01

    The thermonuclear burning rates for the 14 C(α,γ) 18 O radiative capture reaction are calculated at temperatures (0.3 - state, at approximately 9.0 MeV in 18 O as would be deduced from the Yale-Michigan State University measurement of the beta-delayed alpha-particle emission of 18 N and suggested by the Notre Dame-Caltech measurement of the nonresonant 14 C(α,γ) 18 O cross section. The gamma widths of the proposed broad state is estimated using the Alhassid, Gai, and Bertsch sum rule, and an experimental study is proposed

  10. Evaluation of Biomarkers Predictive of Benefit from the PD-1 Inhibitor MK-3475 in Patients with Non-Small Cell Lung Cancer and Brain Metastases

    Science.gov (United States)

    2017-07-01

    Small Cell Lung Cancer and Brain Metastases PRINCIPAL INVESTIGATOR: Sarah B. Goldberg, MD CONTRACTING ORGANIZATION: Yale University New Haven, CT...benefit in patients with non- small cell lung cancer (NSCLC). However, the overall response rate is only 20-30% and there is no clearly-defined...9. Appendices……………………………………………………………14 4 1. INTRODUCTION: Lung cancer is the leading cause of cancer death in the United States, resulting in more

  11. Stuart Hall sobre “hacer estudios culturales”

    OpenAIRE

    Mato, Daniel; Universidad Nacional Tres de Febrero (Untref), Buenos Aires, Argentina

    2016-01-01

    Traducción de Emeshe Juhász MininbergEmeshe Juhász Mininberg es escritora e investigadora independiente. Doctora en Filosofía y Letras, Yale University, Estados Unidos. Traductora y editora de textos de crítica cultural y de artes plásticas. Ha publicado varios artículos sobre ciudadanía, cultura e identidad nacional en tiempos de globalización, que aparecen, entre otros, en Cultura, política y sociedad: perspectivas latinoamericanas (Clacso, 2005) y en el Diccionario de estudios culturales l...

  12. Basic algebra

    CERN Document Server

    Jacobson, Nathan

    2009-01-01

    A classic text and standard reference for a generation, this volume and its companion are the work of an expert algebraist who taught at Yale for two decades. Nathan Jacobson's books possess a conceptual and theoretical orientation, and in addition to their value as classroom texts, they serve as valuable references.Volume I explores all of the topics typically covered in undergraduate courses, including the rudiments of set theory, group theory, rings, modules, Galois theory, polynomials, linear algebra, and associative algebra. Its comprehensive treatment extends to such rigorous topics as L

  13. On Iconography and Attribution of the Loricatus of Salona

    OpenAIRE

    Maršić, Dražen

    2014-01-01

    In 2010 the Croatian public was surprised by the news on the armoured statue (loricatus) of Salona that appeared in a Sotheby's auction. According to the information available on the Internet, the statue was bought by the Frederic J. Iseman Art Trust, a trust of the New York businessman F. J. Iseman. In 2011 the statue was lent to the Metropolitan Museum of Arts in New York, to have been displayed in their Greek and Roman Wing (Figure 1). Till the end of 2015 it is lent to the Yale University...

  14. Reducing the harm of stress: medications to rescue the prefrontal cortex and overcome bad habits: the science of stress: focus on the brain, breaking bad habits, and chronic disease.

    Science.gov (United States)

    Jin, Lu E

    2011-12-01

    Our brain is sensitive to stress. Both acute and chronic stress cause cognitive deficits and induce chronic disorders such as drug addiction. In a June 2011 conference at Yale entitled "The Science of Stress: Focus on the Brain, Breaking Bad Habits, and Chronic Disease," Drs. Amy Arnsten and Sherry Mckee discussed the roles of prefrontal cortex in the treatment of stress impairments and addiction. Medications to strengthen the prefrontal function, such as prazosin and guanfacine, may reduce the harm of stress and help overcome smoking and alcohol abuse.

  15. Personality traits and treatment outcome in obsessive-compulsive disorder Traços de personalidade e resposta terapêutica no transtorno obsessivo-compulsivo

    Directory of Open Access Journals (Sweden)

    Felipe Corchs

    2008-09-01

    Full Text Available OBJECTIVE: Comorbidity with personality disorders in obsessive-compulsive patients has been widely reported. About 40% of obsessive-compulsive patients do not respond to first line treatments. Nevertheless, there are no direct comparisons of personality traits between treatment-responsive and non-responsive patients. This study investigates differences in personality traits based on Cloninger's Temperament and Character Inventory scores between two groups of obsessive-compulsive patients classified according to treatment outcome: responders and non-responders. METHOD: Forty-four responsive and forty-five non-responsive obsessive-compulsive patients were selected. Subjects were considered treatment-responsive (responder group if, after having received treatment with any conventional therapy, they had presented at least a 40% decrease in the initial Yale-Brown Obsessive Compulsive Scale score, had rated "better" or "much better" on the Clinical Global Impressions scale; and had maintained improvement for at least one year. Non-responders were patients who did not achieve at least a 25% reduction in Yale-Brown Obsessive Compulsive Scale scores and had less than minimal improvement on the Clinical Global Impressions scale after having received treatment with at least three selective serotonin reuptake inhibitors (including clomipramine, and at least 20 hours of cognitive behavioral therapy. Personality traits were assessed using Temperament and Character Inventory. RESULTS: Non-responders scored lower in self-directedness and showed a trend to score higher in persistence than responders did. CONCLUSION: This study suggests that personality traits, especially self-directedness, are associated with poor treatment response in obsessive-compulsive patients.OBJETIVO: Comorbidade com transtornos de personalidade tem sido extensamente descrita no transtorno obsessivo-compulsivo. Aproximadamente 40% dos pacientes com transtorno obsessivo-compulsivo n

  16. Patients radiation protection in medical imaging. Conference proceedings

    International Nuclear Information System (INIS)

    2011-12-01

    This document brings together the available presentations given at the conference organised by the French society of radiation protection about patients radiation protection in medical imaging. Twelve presentations (slides) are compiled in this document and deal with: 1 - Medical exposure of the French population: methodology and results (Bernard Aubert, IRSN); 2 - What indicators for the medical exposure? (Cecile Etard, IRSN); 3 - Guidebook of correct usage of medical imaging examination (Philippe Grenier, Pitie-Salpetriere hospital); 4 - Radiation protection optimization in pediatric imaging (Hubert Ducou-Le-Pointe, Aurelien Bouette (Armand-Trousseau children hospital); 5 - Children's exposure to image scanners: epidemiological survey (Marie-Odile Bernier, IRSN); 6 - Management of patient's irradiation: from image quality to good practice (Thierry Solaire, General Electric); 7 - Dose optimization in radiology (Cecile Salvat (Lariboisiere hospital); 8 - Cancer detection in the breast cancer planned screening program - 2004-2009 era (Agnes Rogel, InVS); 9 - Mammographic exposures - radiobiological effects - radio-induced DNA damages (Catherine Colin, Lyon Sud hospital); 10 - Breast cancer screening program - importance of non-irradiating techniques (Anne Tardivon, Institut Curie); 11 - Radiation protection justification for the medical imaging of patients over the age of 50 (Michel Bourguignon, ASN); 12 - Search for a molecular imprint for the discrimination between radio-induced and sporadic tumors (Sylvie Chevillard, CEA)

  17. [The origins of the French neurosurgery].

    Science.gov (United States)

    Brunon, J

    2016-06-01

    Modern French neurosurgery starts at the beginning of the XXth century under the motivation of Joseph Babinski. He submitted his patients to Thierry de Martel who had learned this new specialized area of medicine with H. Cushing in the États-Unis and V. Horsey in Great Britain. His first successfully treated case of an intracranial tumor was published in 1909. But the true founding father was Clovis Vincent, initially a neurologist and collaborator of de Martel, who became the first chairman in 1933 of the neurosurgical department at the Pitié hospital of Paris and the first professor of neurosurgery in 1938. After the Second World War, many departments were created outside of Paris. Neurosurgery was definitively recognized as a specialized area in medicine in 1948. Currently, more than 400 neurosurgeons work in France. Because I had the very great privilege to be present at the birth of this society in 1970 and to still be in contact with some of the second and third generation of French neurosurgeons who led it to its high international recognition, the Chairman of the French Neurosurgical Society asked me to write this short historical vignette. Copyright © 2016 Elsevier Masson SAS. All rights reserved.

  18. Patients radiation protection in medical imaging. Conference proceedings; Radioprotection des patients en imagerie medicale. Recueil des presentations

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-12-15

    This document brings together the available presentations given at the conference organised by the French society of radiation protection about patients radiation protection in medical imaging. Twelve presentations (slides) are compiled in this document and deal with: 1 - Medical exposure of the French population: methodology and results (Bernard Aubert, IRSN); 2 - What indicators for the medical exposure? (Cecile Etard, IRSN); 3 - Guidebook of correct usage of medical imaging examination (Philippe Grenier, Pitie-Salpetriere hospital); 4 - Radiation protection optimization in pediatric imaging (Hubert Ducou-Le-Pointe, Aurelien Bouette (Armand-Trousseau children hospital); 5 - Children's exposure to image scanners: epidemiological survey (Marie-Odile Bernier, IRSN); 6 - Management of patient's irradiation: from image quality to good practice (Thierry Solaire, General Electric); 7 - Dose optimization in radiology (Cecile Salvat (Lariboisiere hospital); 8 - Cancer detection in the breast cancer planned screening program - 2004-2009 era (Agnes Rogel, InVS); 9 - Mammographic exposures - radiobiological effects - radio-induced DNA damages (Catherine Colin, Lyon Sud hospital); 10 - Breast cancer screening program - importance of non-irradiating techniques (Anne Tardivon, Institut Curie); 11 - Radiation protection justification for the medical imaging of patients over the age of 50 (Michel Bourguignon, ASN); 12 - Search for a molecular imprint for the discrimination between radio-induced and sporadic tumors (Sylvie Chevillard, CEA)

  19. Numériser et mettre en ligne

    CERN Document Server

    Claerr, Thierry

    2010-01-01

    Rendre les collections accessibles en ligne est devenu pour les institutions culturelles, d'enseignement et de recherche, un des défis majeurs du début du XXIe siècle. Les projets sont dès à présent nombreux, et concernent tous les types d'établissements et tous les supports. Mener à bien une opération de numérisation et de mise en ligne requiert un ensemble de repères et de connaissances pour l'organisation et la mise en oeuvre d'un projet de numérisation durable. Donner les clés du domaine en se fondant sur des savoirs pratiques et concrets est l'ambition de cet ouvrage, qui fournit un mode opératoire précis pour chacune des grandes étapes à prendre en compte - de la capture à la conservation numérique, en passant par l'interopérabilité, le référencement, et en intégrant l'environnement juridique et réglementaire. Coordonné par Thierry Claerr et Isabelle Westeel, spécialistes du sujet et responsables de formations sur la numérisation et la création de bibliothèques numériques,...

  20. Risperidone for the core symptom domains of autism: results from the study by the autism network of the research units on pediatric psychopharmacology.

    Science.gov (United States)

    McDougle, Christopher J; Scahill, Lawrence; Aman, Michael G; McCracken, James T; Tierney, Elaine; Davies, Mark; Arnold, L Eugene; Posey, David J; Martin, Andrès; Ghuman, Jaswinder K; Shah, Bhavik; Chuang, Shirley Z; Swiezy, Naomi B; Gonzalez, Nilda M; Hollway, Jill; Koenig, Kathleen; McGough, James J; Ritz, Louise; Vitiello, Benedetto

    2005-06-01

    Risperidone has been found efficacious for decreasing severe tantrums, aggression, and self-injurious behavior in children and adolescents with autistic disorder (autism). The authors report on whether risperidone improves the core symptoms of autism, social and communication impairment and repetitive and stereotyped behavior. The database from an 8-week double-blind, placebo-controlled trial (N=101) and 16-week open-label continuation study (N=63) of risperidone for children and adolescents with autism was used to test for drug effects on secondary outcome measures: scores on the Ritvo-Freeman Real Life Rating Scale, the Children's Yale-Brown Obsessive Compulsive Scale, and the maladaptive behavior domain of the Vineland Adaptive Behavior Scales. Compared to placebo, risperidone led to a significantly greater reduction in the overall score on the Ritvo-Freeman Real Life Rating Scale, as well as the scores on the subscales for sensory motor behaviors (subscale I), affectual reactions (subscale III), and sensory responses (subscale IV). No statistically significant difference was observed, however, on the subscale for social relatedness (subscale II) or language (subscale V). Risperidone also resulted in significantly greater reductions in scores on the Children's Yale-Brown Obsessive Compulsive Scale and Vineland maladaptive behavior domain. This pattern of treatment response was maintained for 6 months. Risperidone led to significant improvements in the restricted, repetitive, and stereotyped patterns of behavior, interests, and activities of autistic children but did not significantly change their deficit in social interaction and communication. Further research is necessary to develop effective treatments for the core social and communicative impairments of autism.

  1. Conference Proceedings: Photography and Britishness

    Directory of Open Access Journals (Sweden)

    Sean Willcock

    2016-11-01

    Full Text Available The video-recordings presented here were made at the conference Photography and Britishness, held at the Yale Center for British Art on November 4 – 5, 2016. The conference was the result of a collaboration between the Yale Center for British Art, New Haven, the Paul Mellon Centre for Studies in British Art, London, and the Huntington Library, Art Collections, and Botanical Gardens in San Marino—three research institutions that have a converging interest in British art. The conference sought to investigate the various ways in which notions of “Britishness” have been communicated, inflected, and contested through the photographic image. It was not a conference about the history of photography in Britain, or about British photography. Rather, it sought to consider the nature of the relationship between photography and Britishness: the notion that photography can capture images of Britishness, at the same time that our sense of what Britishness constitutes is produced by the photographic image. A key question for the conference was whether Britishness can have a photographic referent—or whether it is itself an effect of representation. Speakers at the conference approached these questions from a wide range of perspectives and focusing on a diverse number of photographic materials—from family albums and studio portraits to advertisements, reportage, and aerial photography—which demonstrated the complexities and instabilities not only of the term Britishness, but also of the medium of photography. The conference was opened with an introduction by John Tagg. The videos included here are presented in the order they were delivered.

  2. Obsessive compulsive symptoms are associated with better functioning independently of cognition in schizophrenia.

    Science.gov (United States)

    Kontis, Dimitrios; Theochari, Eirini; Nikolakopoulou, Mary; Andreopoulou, Angeliki; Vassos, Dimitrios; Grigoriou, Vasileios; Vassilouli, Spyridoula; Giannakopoulou, Dimitra; Kouloumbi, Maria; Tsaltas, Eleftheria

    2016-10-01

    Although the relationship of obsessive-compulsive symptoms (OCSs) with both cognition and social functioning (SF) has already been the focus of research in schizophrenia, the moderation of the relationship of OCSs with SF by cognition has not been explored to date. We investigated the association of OCSs with SF and its interaction with cognition in schizophrenia. We recruited 110 schizophrenia patients and assessed OCSs (Yale-Brown Scale), schizophrenia symptoms (Positive and Negative Syndrome Scale), SF (Strauss-Carpenter Scale) and cognition. 51 patients had one obsessive-compulsive symptom or more, whereas 59 patients had no obsessive compulsive-symptom, according to the Yale-Brown Scale. We mainly investigated: a) the predictive effect of OCSs on SF, controlling for cognition, illness duration and symptoms' severity and b) the moderating effect of cognition on the OCSs-SF relationship. The mean score of OCSs for patients having at least one symptom was 13.43 (SD=8.32). Higher OCSs predicted increased SF (B=0.98, t=2.41, df=88, p=0.018). This relationship was driven by the association of compulsions with job functioning (B=0.074, t=2.029, df=88, p=0.046). Patients without OCSs demonstrated worse functioning compared with those having at least one obsessive-compulsive symptom (mean difference=2.496, t=3.732, df=88, p<0.001). We failed to find evidence that cognition moderates the effect of OCSs on SF. There may be a beneficial effect of OCSs on SF in patients with schizophrenia which is independent of their cognitive performance. Copyright © 2016 Elsevier Inc. All rights reserved.

  3. Sepsis and meningitis in hospitalized children: performance of clinical signs and their prediction rules in a case-control study.

    Science.gov (United States)

    Verbakel, Jan Y; MacFaul, Roderick; Aertgeerts, Bert; Buntinx, Frank; Thompson, Matthew

    2014-06-01

    Feverish illness is a common presentation to acute pediatric services. Clinical staff faces the challenge of differentiating the few children with meningitis or sepsis from the majority with self-limiting illness. We aimed to determine the diagnostic value of clinical features and their prediction rules (CPR) for identifying children with sepsis or meningitis among those children admitted to a District General Hospital with acute febrile illness. Acutely ill children admitted to a District General Hospital in England were included in this case-control study between 2000 and 2005. We examined the diagnostic accuracy of individual clinical signs and 6 CPRs, including the National Institute for Clinical Excellence "traffic light" system, to determine clinical utility in identifying children with a diagnosis of sepsis or meningitis. Loss of consciousness, prolonged capillary refill, decreased alertness, respiratory effort, and the physician's illness assessment had high positive likelihood ratios (9-114), although with wide confidence intervals, to rule in sepsis or meningitis. The National Institute for Clinical Excellence traffic light system, the modified Yale Observation Scale, and the Pediatric Advanced Warning Score performed poorly with positive likelihood ratios ranging from 1 to 3. The pediatrician's overall illness assessment was the most useful feature to rule in sepsis or meningitis in these hospitalized children. Clinical prediction rules did not effectively rule in sepsis or meningitis. The modified Yale Observation Scale should be used with caution. Single clinical signs could complement these scores to rule in sepsis or meningitis. Further research is needed to validate these CPRs.

  4. Comparison of clinical characteristics of pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections and childhood obsessive-compulsive disorder.

    Science.gov (United States)

    Bernstein, Gail A; Victor, Andrea M; Pipal, Allison J; Williams, Kyle A

    2010-08-01

    The objectives of this study were to identify unique clinical characteristics of children with pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections (PANDAS) compared with a control group of children with non-PANDAS obsessive-compulsive disorder (OCD) with respect to ancillary symptoms, types of obsessions and compulsions, symptom severity, and co-morbid DSM-IV diagnoses. Classification of PANDAS was based on review of pediatric and psychiatric records using the criteria developed by Swedo and colleagues. Children aged 6-14 with PANDAS (n = 21) and non-PANDAS OCD (n = 18) were assessed by blind independent evaluators using the PANDAS Questionnaire, Children's Yale-Brown Obsessive Compulsive Scale, Yale Global Tic Severity Scale, and Anxiety Disorders Interview Schedule for DSM-IV. PANDAS children were significantly more likely to present with separation anxiety, urinary urgency, hyperactivity, impulsivity, deterioration in handwriting, and decline in school performance during their initial episode of neuropsychiatric illness compared with children with OCD. Total tics and vocal tics were more severe in PANDAS children. Separation anxiety disorder and social phobia were more prevalent in non-PANDAS OCD children. Children with non-PANDAS OCD were significantly more likely to include others in their rituals. There were no significant differences between groups on demographics or severity of OCD. Distinguishing clinical characteristics in PANDAS, which included urinary urgency, hyperactivity, impulsivity, and deterioration in handwriting, are linked to basal ganglia functions. These clinical characteristics will aid in the differentiation of PANDAS children for research and clinical purposes and ultimately advance our understanding and treatment of this disorder.

  5. Altered structure of cortical sulci in gilles de la Tourette syndrome: Further support for abnormal brain development.

    Science.gov (United States)

    Muellner, Julia; Delmaire, Christine; Valabrégue, Romain; Schüpbach, Michael; Mangin, Jean-François; Vidailhet, Marie; Lehéricy, Stéphane; Hartmann, Andreas; Worbe, Yulia

    2015-04-15

    Gilles de la Tourette syndrome is a neurodevelopmental disorder characterized by the presence of motor and vocal tics. We hypothesized that patients with this syndrome would present an aberrant pattern of cortical formation, which could potentially reflect global alterations of brain development. Using 3 Tesla structural neuroimaging, we compared sulcal depth, opening, and length and thickness of sulcal gray matter in 52 adult patients and 52 matched controls. Cortical sulci were automatically reconstructed and identified over the whole brain, using BrainVisa software. We focused on frontal, parietal, and temporal cortical regions, in which abnormal structure and functional activity were identified in previous neuroimaging studies. Partial correlation analysis with age, sex, and treatment as covariables of noninterest was performed amongst relevant clinical and neuroimaging variables in patients. Patients with Gilles de la Tourette syndrome showed lower depth and reduced thickness of gray matter in the pre- and post-central as well as superior, inferior, and internal frontal sulci. In patients with associated obsessive-compulsive disorder, additional structural changes were found in temporal, insular, and olfactory sulci. Crucially, severity of tics and of obsessive-compulsive disorder measured by Yale Global Tic severity scale and Yale-Brown Obsessive-Compulsive scale, respectively, correlated with structural sulcal changes in sensorimotor, temporal, dorsolateral prefrontal, and middle cingulate cortical areas. Patients with Gilles de la Tourette syndrome displayed an abnormal structural pattern of cortical sulci, which correlated with severity of clinical symptoms. Our results provide further evidence of abnormal brain development in GTS. © 2015 International Parkinson and Movement Disorder Society.

  6. Insight, Cognitive Insight and Sociodemographic Features in Obsessive Compulsive Disorder Presenting with Reactive and Autogeneus Features

    Directory of Open Access Journals (Sweden)

    Katre ÇAMLI

    2012-03-01

    Full Text Available Objective: The aim of the present study was to test hypothesis that obsessive compulsive disorder (OCD patients who have autogenous obsessions and reactive obsessions show different sociodemographic and clinical characteristics with different insight and cognitive insight levels. Method: Sixty-one patients diagnosed as OCD according to the Structured Clinical Interview for DSM-III-R (SCID-I are recruited. 31 patients had reactive obsessions and 30 had autogenous obsessions. The sociodemographic characteristics of patients and the symptomatology were evaluated using psychiatric scales including SCID-I, Yale Brown Obsessive- Compulsive Scale (YBOCS, Yale Brown Obsessive-Compulsive Scale-Symptom Checklist (YBOCS-SC and Beck Insight Scale. Results: The percentage of women in reactive obsessive group was higher and also this group had significantly less antipsychotic medication prescribed than the autogenous obsessive group. No significant difference was found for the other demographic variables. No significant difference was identified for the Beck Insight Self-Reflectiveness subscale but for the Self-Certainty subscale, reactive obsessives had higher scores. Although there was no significant difference for the composit index points, which is the subtraction of the two subscales, the p value was close to the limit. On the other hand YBOCS item- 11 scores which evaluates insight were higher in autogenous obsessives meaning low levels of insight. Conclusion: For the sociodemographic and clinical characteristics; there was no significant difference between the groups except gender distribution and antipsychotic medication. Our data about insight seems inconsistent but insight and cognitive insight can be different entities which show different levels of insight. Further investigation with different obsession types is needed.

  7. [Experimental physics at Yale University: Research proposal and budget Proposal, 1 January 1992--31 December 1996

    Energy Technology Data Exchange (ETDEWEB)

    1992-07-01

    This report reviews the following topics: nuclear and quark matter; correlated pairs from heavy ion collisions-search for new low mass resonances coupled to electron-positron collisions; proposed light ion research program; experimental nuclear astrophysics (explosive nucleosynthesis); search for rare decay modes and rare processes in nuclei; and nuclear spectroscopy at the extremes of spin, isospin, and temperature. (LSP).

  8. (Experimental physics at Yale University: Research proposal and budget Proposal, 1 January 1992--31 December 1996)

    Energy Technology Data Exchange (ETDEWEB)

    1992-01-01

    This report reviews the following topics: nuclear and quark matter; correlated pairs from heavy ion collisions-search for new low mass resonances coupled to electron-positron collisions; proposed light ion research program; experimental nuclear astrophysics (explosive nucleosynthesis); search for rare decay modes and rare processes in nuclei; and nuclear spectroscopy at the extremes of spin, isospin, and temperature. (LSP).

  9. University Reform in Quebec: The Strike at Laval 1976. Yale Higher Education Research Group Working Paper.

    Science.gov (United States)

    Giles, Geoffrey J.

    Quebec colleges remained firmly entrenched in the pure classicism of prerevolutionary France until well into the twentieth century. Formal Roman Catholic Church control of Laval University, a Jesuit university, ceased in 1965 at a time when the institution and its administration were expanding greatly, and the faculty quickly began to resent the…

  10. [Experimental physics at Yale University: Research proposal and budget Proposal, 1 January 1992--31 December 1996

    International Nuclear Information System (INIS)

    1992-01-01

    This report reviews the following topics: nuclear and quark matter; correlated pairs from heavy ion collisions-search for new low mass resonances coupled to electron-positron collisions; proposed light ion research program; experimental nuclear astrophysics (explosive nucleosynthesis); search for rare decay modes and rare processes in nuclei; and nuclear spectroscopy at the extremes of spin, isospin, and temperature. (LSP)

  11. [Research in elementary particles and interactions

    International Nuclear Information System (INIS)

    Adair, R.; Sandweiss, J.; Schmidt, M.

    1992-05-01

    Research of the Yale University groups in the areas of elementary particles and their interactions are outlined. Work on the following topics is reported: development of CDF trigger system; SSC detector development; study of heavy flavors at TPL; search for composite objects produced in relativistic heavy-ion collisions; high-energy polarized lepton-nucleon scattering; rare K + decays; unpolarized high-energy muon scattering; muon anomalous magnetic moment; theoretical high-energy physics including gauge theories, symmetry breaking, string theory, and gravitation theory; study of e + e - interactions with the SLD detector at SLAC; and the production and decay of particles containing charm and beauty quarks

  12. The Simulation and Correction to the Brain Deformation Based on the Linear Elastic Model in IGS

    Institute of Scientific and Technical Information of China (English)

    MU Xiao-lan; SONG Zhi-jian

    2004-01-01

    @@ The brain deformation is a vital factor affecting the precision of the IGS and it becomes a hotspot to simulate and correct the brain deformation recently.The research organizations, which firstly resolved the brain deformation with the physical models, have the Image Processing and Analysis department of Yale University, Biomedical Modeling Lab of Vanderbilt University and so on. The former uses the linear elastic model; the latter uses the consolidation model.The linear elastic model only needs to drive the model using the surface displacement of exposed brain cortex,which is more convenient to be measured in the clinic.

  13. Tarotkorttien historiaa pelikortteina : kohteena Lady Knight -kortti

    OpenAIRE

    Pylkkö, Ina

    2015-01-01

    Opinnäytetyö käsittelee tarot-korttien historiaa pelikortteina ja Cary-Yale Visconti -tarotpakan Lady Knight -korttia. Opinnäytetyöhön kuuluu toiminnallinen osuus, jossa toteutettiin uusi versio Lady Knight -kortista yhdistämällä digitaalinen maalaus ja kultaus. Tarot-kortteja on tutkittu taidehistorian sekä viestinnän näkökulmasta vain vähän. Opinnäytetyö rajaa ulkopuolelle ennustukseen ja okkultismiin liittyvät teoriat ja keskittyy näin pelin historiaan. Työssä perehdytään ensin taideh...

  14. PO23 - Behavioural therapy via a video conference

    DEFF Research Database (Denmark)

    Grejsen, Judy; Aaslet, Lone; Debes, Nanette Marinette Monique Mol

    2016-01-01

    UNLABELLED: Theme: Therapy and technology Methods: Since December 2014, 10 patients have participated and finished the therapy. The first and last session took place at the Tourette clinic and sessions 2-11 were offered via video conference. Before and after BT, Yale Global Tics Severity Scale...... and PedsQl (Quality of Life) were used to assess the effectiveness of BT. We compared these patients with 10 patients with traditional BT. RESULTS: Both in the group with video conference BT and in the group with traditional BT, we found a decrease in motor, vocal, and total tics and global severity score...

  15. Use of subconjunctival injections of 5-fluorouracil to rescue and prolong intraocular pressure reduction for a failing Ahmed glaucoma implant.

    Science.gov (United States)

    Kaplowitz, Kevin; Khodadadeh, Sarah; Wang, Samantha; Lee, Daniel; Tsai, James C

    2017-06-01

    5-Fluorouracil (5-FU) has been well described for a failing trabeculectomy bleb, but not for aqueous shunts. We sought to determine whether subconjunctival 5-FU prolongs the intraocular pressure (IOP) efficacy of Ahmed shunts. We included all patients with Ahmed FP-7 implantation by one surgeon at Yale University. Patients with  21 on >2 medications. Five-milligram (0.1 cc) injections were made over the plate. The control group consisted of Ahmed FP-7 patients without injections. The main outcome measure was IOP. Secondary outcome was success (IOP Ahmed shunts. Outcomes between eyes receiving injections and controls were statistically similar.

  16. Status Review of Wildlife Mitigation, Columbia Basin Hydroelectric Projects, Washington Facilities (Intrastate) Final Report.

    Energy Technology Data Exchange (ETDEWEB)

    Howerton, Jack

    1984-11-01

    This report was prepared for BPA in fulfillment of section 1004 (b)(1) of the Pacific Northwest Electric Power Planning and Conservation Act of 1980, to review the status of past, present, and proposed future wildlife planning and mitigation program at existing hydroelectric projects in the Columbia River Basin. The project evaluations will form the basis for determining any needed remedial measures or additional project analysis. Projects addressed are: Merwin Dam; Swift Project; Yale Project; Cowlitz River; Boundary Dam; Box Canyon Dam; Lake Chelan; Condit Project; Enloe Project; Spokane River; Tumwater and Dryden Dam; Yakima; and Naches Project.

  17. New York City: A Burning Portrait of Urban America

    Directory of Open Access Journals (Sweden)

    Olivier Walther

    2011-01-01

    Full Text Available The Bonfire of the Vanities tells the story of an encounter that should never have happened, between a Wall Street golden boy, Sherman McCoy, and two young black men from the South Bronx, on a motorway access road. McCoy will be accused of having accidentally hit one of his two attackers with his Mercedes coupé, and will end up losing his job, his friends, and everything he owns. “I’m already dead, or the Sherman McCoy of the McCoy family and Yale and Park Avenue and Wall Street is dead” (576...

  18. Precision lifetime measurements using the recoil distance method

    International Nuclear Information System (INIS)

    Kruecken, R.

    2000-01-01

    The recoil distance method (RDM) for the measurements of lifetimes of excited nuclear levels in the range from about 1 ps to 1,000 ps is reviewed. The New Yale Plunger Device for RDM experiments is introduced and the Differential Decay Curve Method for their analysis is reviewed. Results from recent RDM experiments on SD bands in the mass-190 region, shears bands in the neutron deficient lead isotopes, and ground state bands in the mass-130 region are presented. Perspectives for the use of RDM measurements in the study of neutron-rich nuclei are discussed

  19. Precision Lifetime Measurements Using the Recoil Distance Method

    Science.gov (United States)

    Krücken, R.

    2000-01-01

    The recoil distance method (RDM) for the measurements of lifetimes of excited nuclear levels in the range from about 1 ps to 1000 ps is reviewed. The New Yale Plunger Device for RDM experiments is introduced and the Differential Decay Curve Method for their analysis is reviewed. Results from recent RDM experiments on SD bands in the mass-190 region, shears bands in the neutron deficient lead isotopes, and ground state bands in the mass-130 region are presented. Perspectives for the use of RDM measurements in the study of neutron-rich nuclei are discussed. PMID:27551587

  20. Conference on Representation Theory, Number Theory and Invariant Theory: on the Occasion of Roger Howe’s 70th Birthday

    CERN Document Server

    Kim, Ju-Lee; Zhu, Chen-Bo

    2017-01-01

    This book contains selected papers based on talks given at the "Representation Theory, Number Theory, and Invariant Theory" conference held at Yale University from June 1 to June 5, 2015. The meeting and this resulting volume are in honor of Professor Roger Howe, on the occasion of his 70th birthday, whose work and insights have been deeply influential in the development of these fields. The speakers who contributed to this work include Roger Howe's doctoral students, Roger Howe himself, and other world renowned mathematicians. Topics covered include automorphic forms, invariant theory, representation theory of reductive groups over local fields, and related subjects.

  1. The biometric-based module of smart grid system

    Science.gov (United States)

    Engel, E.; Kovalev, I. V.; Ermoshkina, A.

    2015-10-01

    Within Smart Grid concept the flexible biometric-based module base on Principal Component Analysis (PCA) and selective Neural Network is developed. The formation of the selective Neural Network the biometric-based module uses the method which includes three main stages: preliminary processing of the image, face localization and face recognition. Experiments on the Yale face database show that (i) selective Neural Network exhibits promising classification capability for face detection, recognition problems; and (ii) the proposed biometric-based module achieves near real-time face detection, recognition speed and the competitive performance, as compared to some existing subspaces-based methods.

  2. R806 (part 1)

    CERN Multimedia

    CERN PhotoLab

    1976-01-01

    R806 was designed by the BNL-CERN-Syracuse-Yale Collaboration (Bill Willis spokesman) to study large transverse momentum phenomena, and installed in intersection 8 of the ISR. The main detectors were Lithium foil transition radiation detectors to identify electrons and liquid argon calorimeters to measure the energy of the electrons and photons (among the first such calorimeters to be used in an experiment). In part 1 there were two modules, top and bottom of the horizontal beam pipe; the black vertical pipe contains the cryogenics (LN2 and Lar) and is connected to the two modules with the horizontal piping.

  3. Identification of Emergency Department Visits in Medicare Administrative Claims: Approaches and Implications.

    Science.gov (United States)

    Venkatesh, Arjun K; Mei, Hao; Kocher, Keith E; Granovsky, Michael; Obermeyer, Ziad; Spatz, Erica S; Rothenberg, Craig; Krumholz, Harlan M; Lin, Zhenqui

    2017-04-01

    Administrative claims data sets are often used for emergency care research and policy investigations of healthcare resource utilization, acute care practices, and evaluation of quality improvement interventions. Despite the high profile of emergency department (ED) visits in analyses using administrative claims, little work has evaluated the degree to which existing definitions based on claims data accurately captures conventionally defined hospital-based ED services. We sought to construct an operational definition for ED visitation using a comprehensive Medicare data set and to compare this definition to existing operational definitions used by researchers and policymakers. We examined four operational definitions of an ED visit commonly used by researchers and policymakers using a 20% sample of the 2012 Medicare Chronic Condition Warehouse (CCW) data set. The CCW data set included all Part A (hospital) and Part B (hospital outpatient, physician) claims for a nationally representative sample of continuously enrolled Medicare fee-for-services beneficiaries. Three definitions were based on published research or existing quality metrics including: 1) provider claims-based definition, 2) facility claims-based definition, and 3) CMS Research Data Assistance Center (ResDAC) definition. In addition, we developed a fourth operational definition (Yale definition) that sought to incorporate additional coding rules for identifying ED visits. We report levels of agreement and disagreement among the four definitions. Of 10,717,786 beneficiaries included in the sample data set, 22% had evidence of ED use during the study year under any of the ED visit definitions. The definition using provider claims identified a total of 4,199,148 ED visits, the facility definition 4,795,057 visits, the ResDAC definition 5,278,980 ED visits, and the Yale definition 5,192,235 ED visits. The Yale definition identified a statistically different (p < 0.05) collection of ED visits than all other

  4. Deep brain stimulation for severe treatment-resistant obsessive-compulsive disorder: An open-label case series.

    Science.gov (United States)

    Farrand, Sarah; Evans, Andrew H; Mangelsdorf, Simone; Loi, Samantha M; Mocellin, Ramon; Borham, Adam; Bevilacqua, JoAnne; Blair-West, Scott; Walterfang, Mark A; Bittar, Richard G; Velakoulis, Dennis

    2017-09-01

    Deep brain stimulation can be of benefit in carefully selected patients with severe intractable obsessive-compulsive disorder. The aim of this paper is to describe the outcomes of the first seven deep brain stimulation procedures for obsessive-compulsive disorder undertaken at the Neuropsychiatry Unit, Royal Melbourne Hospital. The primary objective was to assess the response to deep brain stimulation treatment utilising the Yale-Brown Obsessive Compulsive Scale as a measure of symptom severity. Secondary objectives include assessment of depression and anxiety, as well as socio-occupational functioning. Patients with severe obsessive-compulsive disorder were referred by their treating psychiatrist for assessment of their suitability for deep brain stimulation. Following successful application to the Psychosurgery Review Board, patients proceeded to have deep brain stimulation electrodes implanted in either bilateral nucleus accumbens or bed nucleus of stria terminalis. Clinical assessment and symptom rating scales were undertaken pre- and post-operatively at 6- to 8-week intervals. Rating scales used included the Yale-Brown Obsessive Compulsive Scale, Obsessive Compulsive Inventory, Depression Anxiety Stress Scale and Social and Occupational Functioning Assessment Scale. Seven patients referred from four states across Australia underwent deep brain stimulation surgery and were followed for a mean of 31 months (range, 8-54 months). The sample included four females and three males, with a mean age of 46 years (range, 37-59 years) and mean duration of obsessive-compulsive disorder of 25 years (range, 15-38 years) at the time of surgery. The time from first assessment to surgery was on average 18 months. All patients showed improvement on symptom severity rating scales. Three patients showed a full response, defined as greater than 35% improvement in Yale-Brown Obsessive Compulsive Scale score, with the remaining showing responses between 7% and 20%. Deep

  5. Book Reviews

    Directory of Open Access Journals (Sweden)

    Redactie KITLV

    1968-07-01

    Full Text Available - C. von Fürer-Haimendorf, Bernard Pignède, Les Gurungs. Une population himalayenne du Népal. École pratique des hautes études-Sorbonne. Le monde d’outre-mer passé et présent. Études XXI. Mouton & Co. Paris - La Haye 1966. 414 pp., illustrated. - C. von Fürer-Haimendorf, Matthias Hermanns, Die religiös-magische Weltan-schauung der Primtivstamme Indiens. Band II. Die Bhilala, Korku, Gond, Baiga. Franz Steiner Verlag. Wiesbaden 1966. 571 pages, 70 illustrations, 1 map. - J. Gonda, Vidyanand “Videh”, The exposition of the Vedas, vol. I (translated from Hindi, Veda-Samsthana, Ajmer, India, 1964. 133 p. - J. Gonda, Vidyanand “Videh”, The Vedic prayers, translated from Hindi by B. Bhushan Hajela, Veda-Samsthana, Ajmer, India, 1964. 108 p. - Edmund R. Leach, M. Nash et al., Anthropological Studies in Theravada Buddhism. Yale University: South East Asia Studies. Cultural Report Series No. 13 (1966. xiv, 236 pp., with maps, charts, glossary. - Frank M. le Bar, L.M. Hanks, Ethnographic notes on Northern Thailand. Cornell University Southeast Asia Program. Data Paper No. 58. Ithaca, 1965. xi, 94 pp., maps, tables., J.R. Hanks, Lauriston Sharp (eds. - Lorenz G. Löffler, Lucien Bernot, Les paysans arakanais du Pakistan oriental; l’histoire, le monde végétal et l’organisation sociale des réfugiés Marma (Mog. Le Monde d’Outre-Mer Passé et Présent, lère série: Études XVI, Mouton & Co, Paris-La Haye 1967, 793 pp. (en deux volumes. - C.H.M. Nooy-Palm, Donn V. Hart, Southeast Asian birth customs, three studies in human reproduction. Behavior Science Monographs, Human Relations Area Files Press. New Haven, Connecticut 1965. 303 pp., Phya Anuman Rajadhon, Richard J. Coughlin (eds. - J.W. Minderhout, Charles F. Keyes, Isan: Regionalism in northeastern Thailand. Data Paper: nr. 65, Southeast Asia Program, Department of Asian Studies, Cornell University, Ithaca, New York, March 1967. 86 pp. - J.M. Pluvier, Truong Buu Lam, Patterns of

  6. Effects of selective serotonin reuptake inhibitors on thought-action fusion, metacognitions, and thought suppression in obsessive-compulsive disorder.

    Science.gov (United States)

    Besiroglu, Lutfullah; Çetinkaya, Nuralay; Selvi, Yavuz; Atli, Abdullah

    2011-01-01

    We aimed to assess whether cognitive processes change over time in patients with obsessive-compulsive disorder (OCD) receiving selective serotonin reuptake inhibitors without cognitive behavioral therapy and to investigate the factors associated with probable cognitive changes. During the 16 weeks of the study, 55 patients who met the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, criteria for OCD received open-label treatment with sertraline (100-200 mg/d) or fluoxetine (40-80 mg/d) and were assessed using the Yale-Brown Obsessive-Compulsive Scale, Beck Depression Inventory (BDI), Thought-Action Fusion Scale (TAFS), Metacognitions Questionnaire (MCQ-30), and White Bear Suppression Inventory (WBSI). The Yale-Brown Obsessive-Compulsive Scale (P < .001), BDI (P < .001), TAFS morality (P < .005), MCQ-30 (P < .01), and WBSI (P < .005) scores at follow-up were significantly lower than baseline scores. When we excluded OCD patients with depressive disorder (n = 12), statistical significance in paired comparisons for MCQ and WBSI disappeared. Similarly, when OCD patients with religious obsessions (n = 16) were excluded, paired comparisons for MCQ and TAF morality were not statistically significant. Changes in BDI, TAFS morality, MCQ-30, and WBSI (P < .005) were significantly correlated with changes in severity of obsessions, but not that of compulsions. After controlling for the change in depression severity, significant correlations between changes in obsessive and cognitive scales did not continue to have statistical significance. The BDI changes (P < .05) significantly explained the changes in symptom severity in a linear regression model. Our findings suggest that selective serotonin reuptake inhibitors can change appraisals of obsessive intrusions via their effects on negative emotions. Copyright © 2011 Elsevier Inc. All rights reserved.

  7. Risk perception and commitment to reduce global climate change in Spain

    Directory of Open Access Journals (Sweden)

    Rodríguez-Priego, Nuria

    2014-04-01

    Full Text Available An online national survey among the Spanish population (n = 602 was conducted to examine the factors underlying a person’s support for commitments to global climate change reductions. Multiple hierarchical regression analysis was conducted in four steps and a structural equations model was tested. A survey tool designed by the Yale Project on Climate Change Communication was applied in order to build scales for the variables introduced in the study. The results show that perceived consumer effectiveness and risk perception are determinant factors of commitment to mitigating global climate change. However, there are differences in the influence that other factors, such as socio-demographics, view of nature and cultural cognition, have on the last predicted variable.Una encuesta online a la población española (n = 602 examina los factores que predicen el apoyo al compromiso con el medio ambiente por parte de los participantes para reducir el cambio climático global. Se realizó una regresión múltiple jerárquica en cuatro pasos y se testó el modelo de ecuaciones estructurales propuesto. En la encuesta se aplicó una herramienta diseñada por el Yale Project on Climate Change Communication con la finalidad de construir escalas para las variables introducidas en el estudio. Los resultados muestran que la efectividad percibida por el consumidor y el riesgo percibido son factores determinantes del apoyo al compromiso para reducir el cambio climático global. No obstante, se encontraron algunas diferencias en cuanto a la influencia de otros factores tales como las variables socio-demográficas, la visión de la naturaleza y la cognición cultural.

  8. Extravillous trophoblast invasion in placenta accreta is associated with differential local expression of angiogenic and growth factors: a cross-sectional study.

    Science.gov (United States)

    Duzyj, C M; Buhimschi, I A; Laky, C A; Cozzini, G; Zhao, G; Wehrum, M; Buhimschi, C S

    2018-02-22

    Placenta accreta is clinically associated with maternal uterine scar. Our objective was to investigate the biochemical contribution of maternal scarring to hyperinvasive trophoblast. We hypothesised that trophoblast over-invasion in placenta accreta is associated with aberrant invasion-site signalling of growth and angiogenic factors known to be involved in wound healing and promotion of cell invasion through the epithelial to mesenchymal cellular programme. Cross-sectional series. Yale-New Haven Hospital. Women with histologically confirmed normal and abnormal placentation. Placental invasion site tissue sections were immunostained for endoglin and other angiogenic regulators, and transforming growth factor β (TGFβ) proteins. Maternal serum endoglin, and the vascular endothelial growth factor (VEGF) mediators hypoxia-inducible factor-1α (HIF1α) and endostatin, were assessed using immunoassay. Differences in median H-score by immunostaining and in mean serum level by immunoassay. By immunostaining, placenta accreta samples demonstrated intervillous endoglin shedding and increased trophoblast expression of its cleavage protein matrix metalloproteinase-14. Absent decidual HIF1α and endostatin were observed in areas of VEGF upregulation. TGFβ1 was present in myocytes but not in collagen bundles into which accreta trophoblast invaded. Maternal serum endoglin decreased in praevia and accreta when corrected for gestational age. Angiogenic and growth factors at the placental invasion site are altered in accreta, both by decidual absence and within myometrial scar. We postulate this promotes the invasive phenotype of placenta accreta by activating hyperinvasive trophoblast and by dysregulating placental vascular remodelling. Yale Department of Obstetrics, Gynecology and Reproductive Sciences funds. Placenta accreta histology shows dysregulation of angiogenic and growth factors. © 2018 Royal College of Obstetricians and Gynaecologists.

  9. The effect of a bidirectional exchange on faculty and institutional development in a global health collaboration.

    Directory of Open Access Journals (Sweden)

    Benjamin E Bodnar

    Full Text Available The MUYU Collaboration is a partnership between Mulago Hospital-Makerere University College of Health Sciences (M-MakCHS, in Kampala, Uganda, and the Yale University School of Medicine. The program allows Ugandan junior faculty to receive up to 1 year of subspecialty training within the Yale hospital system. The authors performed a qualitative study to assess the effects of this program on participants, as well as on M-MakCHS as an institution.Data was collected via semi-structured interviews with exchange participants. Eight participants (67% of those eligible as of 4/2012 completed interviews. Study authors performed data analysis using standard qualitative data analysis techniques.Analysis revealed themes addressing the benefits, difficulties, and opportunities for improvement of the program. Interviewees described the main benefit of the program as its effect on their fund of knowledge. Participants also described positive effects on their clinical practice and on medical education at M-MakCHS. Most respondents cited financial issues as the primary difficulty of participation. Post-participation difficulties included resource limitations and confronting longstanding institutional and cultural habits. Suggestions for programmatic improvement included expansion of the program, ensuring appropriate management of pre-departure expectations, and refinement of program mentoring structures. Participants also voiced interest in expanding post-exchange programming to ensure both the use of and the maintenance of new capacity.The MUYU Collaboration has benefitted both program participants and M-MakCHS, though these benefits remain difficult to quantify. This study supports the assertion that resource-poor to resource-rich exchanges have the potential to provide significant benefits to the resource-poor partner.

  10. Acute Worsening of Tics on Varenicline.

    Science.gov (United States)

    Mittal, Shivam Om; Klassen, Bryan T; Hassan, Anhar; Bower, James H; Coon, Elizabeth A

    The aim of this study was to report worsening of Tourette syndrome (TS) in 2 patients treated with varenicline. Abnormal dopaminergic signaling is likely involved in the pathophysiology of TS. Varenicline is a partial α4β2 nicotinic acetylcholine agonist that enhances dopamine release. Therefore, the use of varenicline may influence tics in patients with TS. We analyzed and described 2 case studies on patients with significant worsening of tics after treatment with varenicline. Patient 1 had motor tics in childhood, which completely resolved by the age of 20 years. At the age of 25 years, he started varenicline and stopped smoking. Within 2 weeks, he developed motor followed by vocal tics that persisted despite stopping varenicline and restarting smoking. The tics were complex, medically refractory, and caused severe disability at work and school (Yale Global Tic Severity Scale score, 86). Patient 2 developed motor and vocal tics in adolescence that persisted into her 20s and caused significant disability in association with psychiatric comorbidities. At the age of 31 years, she started varenicline to quit smoking, which led to a marked increase in tic frequency and severity. Varenicline was discontinued after 3 weeks with improvement to baseline tic severity (Yale Global Tic Severity Scale score, 94). Ultimately, both patients successfully underwent deep brain stimulation to bilateral centromedian/parafascicular complex thalamic nuclei for medically refractory TS. We report 2 patients with motor and/or vocal tics that had severe worsening of tics after varenicline use. This may be due to varenicline-induced increased striatal dopamine in conjunction with nicotine cessation, influencing dopamine receptor sensitivity in TS. Providers should be cautious in prescribing varenicline to patients with TS.

  11. Book Reviews

    Directory of Open Access Journals (Sweden)

    Th. Heesterman-Visser

    1967-04-01

    Full Text Available - J. van Baal, P. Lawrence, Gods ghosts and men in Melanesia; Some religions of Australian New Guinea and the New Hebrides. Melbourne, Oxford University Press, London, Wellington, New York 1965. 298 pp., M.J. Meggitt (eds. - R.S. Wassing, V.F.P.M. van Amelsvoort, Culture, stone age and modern medicine. The early introduction of integrated rural health in a non-literate society. A New Guinea case study in medical anthropology. Van Gorcum & Comp. N.V., Assen 1964. 245 blz., ill., krtn. - P. van Emst, R.G. Crocombe, Land tenure in the Cook Islands. Oxford University Press, Melbourne 1964. 180 blz. - H.J.M. Claessen, N.J.B. Plomley, Friendly mission: The Tasmanian journals and papers of George Augustus Robinson, 1829-1834. Tasmanian Historical Research Association. 1966. 1074 pp., 17 plates, 36 maps. - J.C. Anceaux, John U. Wolff, Beginning Cebuano. Part I. (Yale Linguistic Series, 9. Yale University Press. New Haven & London 1966. 685 pp. - J.C. Anceaux, G.B. Milner, Samoan dictionary, Samoan-English, English-Samoan. Oxford University Press, London, 1966. 465 pp. - L. Sluimers, J.G. Keyes, A bibliography of western-language publications concerning North Vietnam in the Cornell University Library. (Supplement to Data Paper: No. 47, A bibliography of North-Vietnamese publications in the Cornell University Library, September 1962. Data Paper: No. 63, Southeast Asia Program. Department of Asian Studies. Ithaca, Cornell University, 1966. XII, 280 blz., XIV. - Th. Heesterman-Visser, H.A.P.C. Oomen, Eten om te leven. N.V. De Arbeiderspers voor N.O.V.I.B., Amsterdam 1965. 130 foto’s met tekst., B. Lawson (eds.

  12. Resident career planning needs in internal medicine: a qualitative assessment.

    Science.gov (United States)

    Garcia, Rina L; Windish, Donna M; Rosenbaum, Julie R

    2010-12-01

    Few residency programs have centralized resources for career planning. As a consequence, little is known about residents' informational needs regarding career planning. To examine career preparation stressors, practical needs, and information that residents wished they were privy to when applying. In 2007 and 2008, we surveyed 163 recent graduates or graduating residents from 10 Yale-based and Yale-affiliated hospitals' internal medicine programs regarding their experiences with applying for positions after residency. We included questions about demographics, mentorship, stress of finding a job or fellowship, and open-ended questions to assess barriers and frustrations. Qualitative data were coded independently and a classification scheme was negotiated by consensus. A total of 89 residents or recent graduates responded, and 75% of them found career planning during residency training at least somewhat stressful. Themes regarding the application process included (1) knowledge about the process, (2) knowledge about career paths and opportunities, (3) time factors, (4) importance of adequate personal guidance and mentorship, and (5) self-knowledge regarding priorities and the desired outcome. Residents identified the following advice as most important: (1) start the process as early as possible and with a clear knowledge of the process timeline, (2) be clear about personal goals and priorities, and (3) be well-informed about a prospective employer and what that employer is looking for. Most residents felt career planning should be structured into the curriculum and should occur in the first year or throughout residency. This study highlights residents' desire for structured dissemination of information and counseling with regard to career planning during residency. Our data suggest that exposure to such resources may be beneficial as early as the first year of training.

  13. Body Dysmorphic Symptoms Scale for patients seeking esthetic surgery: cross-cultural validation study

    Directory of Open Access Journals (Sweden)

    Tatiana Dalpasquale Ramos

    Full Text Available ABSTRACT: CONTEXT AND OBJECTIVE: Rhinoplasty is one of the most sought-after esthetic operations among individuals with body dysmorphic disorder. The aim of this study was to cross-culturally adapt and validate the Body Dysmorphic Symptoms Scale. DESIGN AND SETTING: Cross-cultural validation study conducted in a plastic surgery outpatient clinic of a public university hospital. METHODS: Between February 2014 and March 2015, 80 consecutive patients of both sexes seeking rhinoplasty were selected. Thirty of them participated in the phase of cultural adaptation of the instrument. Reproducibility was tested on 20 patients and construct validity was assessed on 50 patients, with correlation against the Yale-Brown Obsessive Compulsive Scale for Body Dysmorphic Disorder. RESULTS: The Brazilian version of the instrument showed Cronbach's alpha of 0.805 and excellent inter-rater reproducibility (intraclass correlation coefficient, ICC = 0.873; P < 0.001 and intra-rater reproducibility (ICC = 0.939; P < 0.001. Significant differences in total scores were found between patients with and without symptoms (P < 0.001. A strong correlation (r = 0.841; P < 0.001 was observed between the Yale-Brown Obsessive Compulsive Scale for Body Dysmorphic Disorder and the Body Dysmorphic Symptoms Scale. The area under the receiver operating characteristic curve was 0.981, thus showing good accuracy for discriminating between presence and absence of symptoms of body dysmorphic disorder. Forty-six percent of the patients had body dysmorphic symptoms and 54% had moderate to severe appearance-related obsessive-compulsive symptoms. CONCLUSIONS: The Brazilian version of the Body Dysmorphic Symptoms Scale is a reproducible instrument that presents face, content and construct validity.

  14. The suicidality continuum in a large sample of obsessive-compulsive disorder (OCD) patients.

    Science.gov (United States)

    Velloso, P; Piccinato, C; Ferrão, Y; Aliende Perin, E; Cesar, R; Fontenelle, L; Hounie, A G; do Rosário, M C

    2016-10-01

    Obsessive-compulsive disorder (OCD) has a chronic course leading to huge impact in the patient's functioning. Suicidal thoughts and attempts are much more frequent in OCD subjects than once thought before. To empirically investigate whether the suicidal phenomena could be analyzed as a suicidality severity continuum and its association with obsessive-compulsive (OC) symptom dimensions and quality of life (QoL), in a large OCD sample. Cross-sectional study with 548 patients diagnosed with OCD according to the DSM-IV criteria, interviewed in the Brazilian OCD Consortium (C-TOC) sites. Patients were evaluated by OCD experts using standardized instruments including: Yale-Brown Obsessive-Compulsive Scale (YBOCS); Dimensional Yale-Brown Obsessive-Compulsive Scale (DYBOCS); Beck Depression and Anxiety Inventories; Structured Clinical Interview for DSM-IV (SCID); and the SF-36 QoL Health Survey. There were extremely high correlations between all the suicidal phenomena. OCD patients with suicidality had significantly lower QoL, higher severity in the "sexual/religious", "aggression" and "symmetry/ordering" OC symptom dimensions, higher BDI and BA scores and a higher frequency of suicide attempts in a family member. In the regression analysis, the factors that most impacted suicidality were the sexual dimension severity, the SF-36 QoL Mental Health domain, the severity of depressive symptoms and a relative with an attempted suicide history. Suicidality could be analyzed as a severity continuum and patients should be carefully monitored since they present with suicidal ideation. Lower QoL scores, higher scores on the sexual dimension and a family history of suicide attempts should be considered as risk factors for suicidality among OCD patients. Copyright © 2016 Elsevier Masson SAS. All rights reserved.

  15. Deep brain stimulation of the antero-medial globus pallidus interna for Tourette syndrome.

    Directory of Open Access Journals (Sweden)

    Perminder S Sachdev

    Full Text Available BACKGROUND: We have previously reported the results of Deep Brain Stimulation (DBS of the antero-medial globus pallidus interna (GPi for severe Tourette Syndrome (TS in 11 patients. We extend this case series to 17 patients and a longer follow-up to a maximum of 46 months. METHODS: 17 patients (14 male; mean age 29.1 years, range 17-51 years with severe and medically intractable TS were implanted with Medtronic quadripolar electrodes bilaterally in the antero-medial GPi. The primary outcome measure was the Yale Global Tic Severity Scale (YGTSS. Secondary outcome measures included the Yale-Brown Obsessive Compulsive Scale, Hamilton Depression Rating Scale, Gilles de la Tourette Quality of Life Scale and Global Assessment of Functioning. Follow up was at one month, three months and finally at a mean 24.1 months (range 8-46 months following surgery. RESULTS: Overall, there was a 48.3% reduction in motor tics and a 41.3% reduction in phonic tics at one month, and this improvement was maintained at final follow-up. 12 out of 17 (70.6% patients had a>50% reduction in YGTSS score at final follow up. Only 8 patients required ongoing pharmacotherapy for tics post-surgery. Patients improved significantly on all secondary measures. Adverse consequences included lead breakage in 4 patients, infection (1, transient anxiety (2, dizziness (1, poor balance (1 and worsening of stuttering (1. CONCLUSIONS: This case series provides further support that antero-medial GPi DBS is an effective and well tolerated treatment for a subgroup of severe TS, with benefits sustained up to 4 years.

  16. HENRY C. WALLICH: A THIRD GENERATION BANKER

    Directory of Open Access Journals (Sweden)

    Saul Engelbourg

    2001-01-01

    Full Text Available Born in Germany and descendant of a wealthy banking family, Henry C. Wallich emigrated to the United States like others of Jewish ancestry who fled during the 1930s. A professor of money and banking at Yale for two decades, Wallich capped his career as a Governor of the Federal Reserve. During the stagflation of the late 1960s, Wallich, a dissenter, tirelessly advocated tighter monetary policy to stem inflation. Always a scholar, Wallich published extensively; he also served as the Fed’s public spokesman. Owing to his Harvard doctorate and his eminence as an economist, Wallich knew everyone worth knowing in the economics profession.

  17. An MPCA/LDA Based Dimensionality Reduction Algorithm for Face Recognition

    Directory of Open Access Journals (Sweden)

    Jun Huang

    2014-01-01

    Full Text Available We proposed a face recognition algorithm based on both the multilinear principal component analysis (MPCA and linear discriminant analysis (LDA. Compared with current traditional existing face recognition methods, our approach treats face images as multidimensional tensor in order to find the optimal tensor subspace for accomplishing dimension reduction. The LDA is used to project samples to a new discriminant feature space, while the K nearest neighbor (KNN is adopted for sample set classification. The results of our study and the developed algorithm are validated with face databases ORL, FERET, and YALE and compared with PCA, MPCA, and PCA + LDA methods, which demonstrates an improvement in face recognition accuracy.

  18. Robust Face Recognition Based on Texture Analysis

    Directory of Open Access Journals (Sweden)

    Sanun Srisuk

    2013-01-01

    Full Text Available In this paper, we present a new framework for face recognition with varying illumination based on DCT total variation minimization (DTV, a Gabor filter, a sub-micro-pattern analysis (SMP and discriminated accumulative feature transform (DAFT. We first suppress the illumination effect by using the DCT with the help of TV as a tool for face normalization. The DTV image is then emphasized by the Gabor filter. The facial features are encoded by our proposed method - the SMP. The SMP image is then transformed to the 2D histogram using DAFT. Our system is verified with experiments on the AR and the Yale face database B.

  19. Parity violating weak neutral current effects in elastic e-12C scattering. Progress report, January 1, 1983-April 15, 1984

    International Nuclear Information System (INIS)

    Lubell, M.S.

    1984-01-01

    The polarized electron source, which was designed at Yale, features full compatibility with the MIT-Bates accelerator with an injection energy of 365 keV, matching time structures, a approx. 1% duty cycle, and peak beam intensities in the range of 5 to 50 mA peak current. The experimental method utilizes photoemission from a GaAs crystal prepared to have a negative electron affinity in an ultrahigh vacuum system with base pressures of 10 -10 torr or below. A high power continuous wave krypton-ion laser in conjunction with electro-optical instrumentation to chop the beam and to allow random polarization reversal is used as a light source

  20. Some final thoughts

    Science.gov (United States)

    Frame, Michael

    2015-03-01

    One afternoon Benoit invited me to a master's tea in his college at Yale. He and a group of colleagues discussed opera, the distribution of galaxies, Hokusai's art, Stoppard's Arcadia, many other topics. Despite the conversation's swerves, Benoit contributed detailed opinions to each new direction. When he excused himself to speak with someone on the other side of the room, a diminuitive Cuban poet who joined the group late turned to me, clearly Benoit's guest, and asked, "Who is that enormous man?" Before I could reply, another said, "Oh, that's Benoit Mandelbrot. He reinvented geometry." "Ah, a scientist. Then why does he know opera and art?"...

  1. Das Meer im Recht

    Directory of Open Access Journals (Sweden)

    Daniel Damler

    2010-01-01

    Full Text Available Rezensierte Werke:Jack P. Greene, Philip D. Morgan (Hg., Atlantic History. A Critical Appraisal, Oxford: Oxford University Press 2009, 371 S., ISBN 978-0-19-532034-2; John H. Elliott, Empires of the Atlantic world. Britain and Spain in America 1492–1830, New Haven, London: Yale University Press 2006, 546 S., ISBN 0-300-11431-1; Bernard Bailyn, Atlantic History. Concept and Contours, Cambridge (MA, London: Harvard University Press 2005, 149 S., ISBN 0-674-01688-2; Horst Pietschmann (Hg., Atlantic History. History of the Atlantic System 1580–1830, Göttingen: Vandenhoeck & Ruprecht 2002, 556 S., ISBN3-525-86318-7

  2. In memory of Professor Tianqin Cao(Tien-chin Tsao)

    Institute of Scientific and Technical Information of China (English)

    Youshang Zhang

    2010-01-01

    @@ In December this year,the 4th Tianqin Cao Memorial Symposium on Protein Research will be held in Xiamen(Amoy).On this occasion,it is my pleasure to write a recollection in memory of Professor Tianqin Cao.It was rather late when Ⅰ was able to study in Prof.Cao's laboratory as a graduate student in the Institute of Biochemistry.After graduating from the Department of Chemical Engineering of Zhejiang University in 1948,Ⅰ could not find a job in a chemical engineering factory; therefore,Ⅰ changed my profession to biochemistry and worked as an assistant in the Department of Biochemistry of Hunan Yale Medical College.

  3. Polarized proton acceleration program at the AGS

    International Nuclear Information System (INIS)

    Lee, Y.Y.

    1981-01-01

    The unexpected importance of high energy spin effects and the success of the ZGS in correcting many intrinsic and imperfection depolarizing resonances led us to attempt to accelerate polarized protons in the AGS. A multi-university/laboratory collaborative effort involving Argonne, Brookhaven, Michigan, Rice and Yale is underway to improve and modify to accelerate polarized protons. From the experience at the ZGS and careful studies made us confident of the feasibility of achieving a polarization of over 60 percent up to 26 GeV/c with an intensity of 10 11 approx. 10 12 per pulse. The first polarized proton acceleration at the AGS is expected in 1983

  4. Close companion to α Ursae Majoris

    International Nuclear Information System (INIS)

    Kondo, Y.; Morgan, T.H.; Modisette, J.L.

    1977-01-01

    After our recent article on the chromospheric emission features of the Mg II resonance doublet near 2800 A observed in α UMa, Bidelman pointed out to us that this star's close companion is considerably brighter than is stated in the Yale Catalogue of Bright Stars. We have synthesized the Mg II feature for this star from the Mg II observations obtained in other single stars. The results show that the close companion to α UMa is late A in type, in general agreement with the spectroscopic studies. This explains the apparent discrepancy in the Mg II doublet emission strengths between α UMa and β Gem

  5. Performance of Ruecking's Word-compression Method When Applied to Machine Retrieval from a Library Catalog

    Directory of Open Access Journals (Sweden)

    Ben-Ami Lipetz

    1969-12-01

    Full Text Available F. H. Ruecking's word-compression algorithm for retrieval of bibliographic data from computer stores was tested for performance in matching user-supplied, unedited bibliographic data to the bibliographic data contained in a library catalog. The algorithm was tested by manual simulation, using data derived from 126 case studies of successful manual searches of the card catalog at Sterling Memorial Library, Yale University. The algorithm achieved 70% recall in comparison to conventional searching. Its accepta- bility as a substitute for conventional catalog searching methods is ques- tioned unless recall performance can be improved, either by use of the algorithm alone or in combination with other algorithms.

  6. 76 FR 62833 - Notice of Intent To Repatriate a Cultural Item: Peabody Museum of Natural History, Yale...

    Science.gov (United States)

    2011-10-11

    ... consultation with the appropriate Indian tribe, has determined that the cultural item meets the definition of... University, New Haven, CT, that meets the definition of unassociated funerary object under 25 U.S.C. 3001... Northwest Coast culture area, the recovery of the blanket from a grave pole, and the type of object (chilkat...

  7. Face validity and inter-rater reliability of the Danish version of the modified-Yale Preoperative Anxiety Scale

    DEFF Research Database (Denmark)

    Skovby, Pernille; Rask, Charlotte Ulrikka; Dall, Rolf

    2014-01-01

    -YPAS to Danish cultural and linguistic conditions and to test face validity and inter-reliability in a clinical setting. Materials and methods The translation was performed in accordance with WHO guidelines. Face validity as well as linguistic difficulties of the Danish version was tested and solved in a focus...... of the m-YPAS as suitable and relevant, i.e. the face validity satisfactory. Inter-rater reliability analysis revealed that inter-observer agreement at induction 1 were good to very good (kw: 0.63–0.98) and at induction 2, the agreement was good to very good (kw: 0.72–0.96). ICC for the overall weighted...... anxiety score was in: induction 1:0.92 and induction 2: 0.92 Conclusion Standardized and validated assessment tools are needed to evaluate interventions aiming to reduce preoperative anxiety in children. The Danish m-YPAS had a satisfactory face validity and inter-reliability, based on a minor empirical...

  8. Interactive radiopharmaceutical facility between Yale Medical Center and Brookhaven National Laboratory. Progress report, June 1981-July 1982

    Energy Technology Data Exchange (ETDEWEB)

    Gottschalk, A

    1982-01-01

    Progress is reported in the following research areas: (1) evaluation of /sup 14/C-labelled carboxyethyl ester 2-cardoxy methyl ester of arachidonic acid; (2) the effects of drug intervention on cardiac inflammatory response following experimental myocardial infarction using indium-111 labeled autologous leukoyctes; (3) the evaluation of /sup 97/Ru-oxine to label human platelets in autologous plasma; and (4) the specific in vitro radiolabeling of human neutrophils. (ACR)

  9. Interactive radiopharmaceutical facility between Yale Medical Center and Brookhaven National Laboratory. Progress report, September 1980-April 1981

    International Nuclear Information System (INIS)

    Gottschalk, A.

    1981-01-01

    Progress made in the past eight months is reported for the following research areas: (1) the evaluation of 11 C labeled acid-ester analogue of arachidonic acid (AA) as a potential agent for the studies of cardiac pathophysiology; and (2) the evaluation of new radioactive agents for improving methods of radiolabeling cellular blood elements

  10. Web-Based Intervention to Teach Developmentally Supportive Care to Parents of Preterm Infants: Feasibility and Acceptability Study.

    Science.gov (United States)

    Luu, Thuy Mai; Xie, Li Feng; Peckre, Perrine; Cote, Sylvana; Karsenti, Thierry; Walker, Claire-Dominique; Gosselin, Julie

    2017-11-30

    Preterm birth affects 8% to 11% of the population and conveys a significant risk of developmental delays. Intervention programs that support child development have been shown to have a positive impact on early motor and cognitive development and on parental well-being. However, these programs are often difficult to implement in a real-life setting due to lack of resources. Hence, our multidisciplinary team developed Mieux Agir au Quotidien (MAQ) to teach developmentally supportive care to parents of preterm infants with the goal of improving child development and parental outcomes. Our intervention included 3 in-person workshops that occurred prior to hospital discharge and a Web-based platform with written and videotaped materials that addressed 5 main themes: (1) infant behavioral cues, (2) flexion positioning; (3) oral feeding support, (4) parent-infant interactions, and (5) anticipation of developmental milestones. This study aimed to test the feasibility and acceptability of the intervention by parents of preterm infants and assess clinical benefits on child neurodevelopment and parental outcomes during the first year of life. A total of 107 infants born at children and investigate how Web-based technologies can efficiently complement individualized intervention to alleviate the burden on health care resources. ©Thuy Mai Luu, Li Feng Xie, Perrine Peckre, Sylvana Cote, Thierry Karsenti, Claire-Dominique Walker, Julie Gosselin. Originally published in JMIR Research Protocols (http://www.researchprotocols.org), 30.11.2017.

  11. Três comédias de Shakespeare pela ótica do Stablex

    Directory of Open Access Journals (Sweden)

    Marly Gondim Cavalcanti Souza

    2012-09-01

    Full Text Available http://dx.doi.org/10.5007/2176-8552.2011nesp1p119 Pretende-se, neste estudo, proceder a análise de três comédias de William Shakespeare, pela ótica do método de análise lexical, textual e discursiva, aplicando, especificamente, a ferramenta matemático-estatístico-computacional, denominada Stablex, de autoria de André Camlong e Thierry Beltran (2004.Toma-se como viés de análise o aspecto musical presente no texto das três peças teatrais. Metodologicamente, trilhou-se o caminho do estudo comparativo entre as obras shakespearianas, tendo como horizonte a colaboração da música na expressão verbal dos textos teatrais do autor inglês, com o intuito de localizar os vocabulários preferenciais e o peso dos itens lexicais relacionados à música, na obra do talvez mais famoso escritor de língua inglesa. O fundamento para as evidências musicais repousa sobre a teoria e a história da música, bem como nos seus elementos básicos. As teorias tomadas como alicerce deste estudo são as de: Jean-Louis Cupers (1988, Arroyas (2001, Solange Oliveira (2002, André Camlong (1996 e Steven Paul Scher (apud OLIVEIRA, 2002.

  12. Performance assessment, participative processes and value judgements. Report from the first RISCOM II workshop

    Energy Technology Data Exchange (ETDEWEB)

    Andersson, Kjell [Karinta-Konsult, Taeby (Sweden); Lilja, Christina [Swedish Nuclear Power Inspectorate, Stockholm (Sweden)] (eds.)

    2001-12-01

    This workshop was the first one in a series of three workshops within the RISCOM-II project. The aim was to gather the status of the project as a starting point to enhance discussions between project participants and with a number of invited participants. The seminar also included two presentations from the OECD/NEA on NEA work related to stake holder participation, as well as the EC Concerted Action COWAM. Discussions were held in direct connection to the talks and in special sessions. The first day of the workshop entitled Value judgements,risk communication and performance assessment was moderated by Magnus Westerlind (SKI), the RISCOM-II coordinator. The second day was entitled Case studies exploring implications for the practical development of risk communication and was moderated by Anna Littleboy, UK Nirex Ltd. The workshop was opened by Thierry Devries, EDF. He welcomed the participants to Paris and gave some remarks about the French nuclear waste management situation and highlighted the significant French and EDF participation in RISCOM-II. He meant that the project should have possibilities to enhance transparency in nuclear waste programmes and noted that the new concept of stretching, introduced by RISCOM, is already is use. In the following the talks given at the workshop and the discussion that took place are summarized. Appendix 3 gives a brief overview of the RISCOM-II project.

  13. Minimally invasive devices for treating lower urinary tract symptoms in benign prostate hyperplasia: technology update

    Directory of Open Access Journals (Sweden)

    Aoun F

    2015-08-01

    Full Text Available Fouad Aoun1, Quentin Marcelis,1,2 Thierry Roumeguère,2 1Department of Urology, Jules Bordet Institute, 2Department of Urology, Erasme Hospital, University Clinics of Brussels, Université Libre de Bruxelles, Brussels, Belgium Abstract: Benign prostatic hyperplasia (BPH represents a spectrum of related lower urinary tract symptoms (LUTS. The cost of currently recommended medications and the discontinuation rate due to side effects are significant drawbacks limiting their long-term use in clinical practice. Interventional procedures, considered as the definitive treatment for BPH, carry a significant risk of treatment-related complications in frail patients. These issues have contributed to the emergence of new approaches as alternative options to standard therapies. This paper reviews the recent literature regarding the experimental treatments under investigation and presents the currently available experimental devices and techniques used under local anesthesia for the treatment of LUTS/BPH in the vast majority of cases. Devices for delivery of thermal treatment (microwaves, radiofrequency, high-intensity focused ultrasound, and the Rezum system, mechanical devices (prostatic stent and urethral lift, fractionation of prostatic tissue (histotripsy and aquablation, prostate artery embolization, and intraprostatic drugs are discussed. Evidence for the safety, tolerability, and efficacy of these “minimally invasive procedures” is analyzed. Keywords: lower urinary tract symptoms (LUTS, benign prostatic hyperplasia (BPH, minimally invasive therapies, new approaches, experimental therapy

  14. Experimental and theoretical investigation of Fe-catalysis phenomenon in hydrogen thermal desorption from hydrocarbon plasma-discharge films from T-10 tokama

    Science.gov (United States)

    Stankevich, Vladimir G.; Sukhanov, Leonid P.; Svechnikov, Nicolay Yu.; Lebedev, Alexey M.; Menshikov, Kostantin A.; Kolbasov, Boris N.

    2017-10-01

    Investigations of the effect of Fe impurities on D2 thermal desorption (TD) from homogeneous CDx films (x ˜ 0.5) formed in the D-plasma discharge of the T-10 tokamak were carried out. The experimental TD spectra of the films showed two groups of peaks at 650-850 K and 900-1000 K for two adsorption states. The main result of the iron catalysis effect consists in the shift of the high-temperature peak by -24 K and in the increase in the fraction of the weakly bonded adsorption states. To describe the effect of iron impurities on TD of hydrogen isotopes, a structural cluster model based on the interaction of the Fe+ ion with the 1,3-C6H8 molecule was proposed. The potential energy surfaces of chemical reactions with the H2 elimination were calculated using ab initio methods of quantum chemistry. It was established that the activation barrier of hydrogen TD is reduced by about 1 eV due to the interaction of the Fe+ ion with the π-subsystem of the 1,3-C6H8 molecule leading to a redistribution of the double bonds along the carbon system. Contribution to the topical issue "Plasma Sources and Plasma Processes (PSPP)"", edited by Luis Lemos Alves, Thierry Belmonte and Tiberiu Minea

  15. Fungal biology: compiling genomes and exploiting them

    Energy Technology Data Exchange (ETDEWEB)

    Labbe, Jessy L [ORNL; Uehling, Jessie K [ORNL; Payen, Thibaut [INRA; Plett, Jonathan [University of Western Sydney, Australia

    2014-01-01

    The last 10 years have seen the cost of sequencing complete genomes decrease at an incredible speed. This has led to an increase in the number of genomes sequenced in all the fungal tree of life as well as a wide variety of plant genomes. The increase in sequencing has permitted us to study the evolution of organisms on a genomic scale. A number of talks during the conference discussed the importance of transposable elements (TEs) that are present in almost all species of fungi. These TEs represent an especially large percentage of genomic space in fungi that interact with plants. Thierry Rouxel (INRA, Nancy, France) showed the link between speciation in the Leptosphaeria complex and the expansion of TE families. For example in the Leptosphaeria complex, one species associated with oilseed rape has experienced a recent and massive burst of movement by a few TE families. The alterations caused by these TEs took place in discrete regions of the genome leading to shuffling of the genomic landscape and the appearance of genes specific to the species, such as effectors useful for the interactions with a particular plant (Rouxel et al., 2011). Other presentations showed the importance of TEs in affecting genome organization. For example, in Amanita different species appear to have been invaded by different TE families (Veneault-Fourrey & Martin, 2011).

  16. Performance assessment, participative processes and value judgements. Report from the first RISCOM II workshop

    International Nuclear Information System (INIS)

    Andersson, Kjell; Lilja, Christina

    2001-12-01

    This workshop was the first one in a series of three workshops within the RISCOM-II project. The aim was to gather the status of the project as a starting point to enhance discussions between project participants and with a number of invited participants. The seminar also included two presentations from the OECD/NEA on NEA work related to stake holder participation, as well as the EC Concerted Action COWAM. Discussions were held in direct connection to the talks and in special sessions. The first day of the workshop entitled Value judgements,risk communication and performance assessment was moderated by Magnus Westerlind (SKI), the RISCOM-II coordinator. The second day was entitled Case studies exploring implications for the practical development of risk communication and was moderated by Anna Littleboy, UK Nirex Ltd. The workshop was opened by Thierry Devries, EDF. He welcomed the participants to Paris and gave some remarks about the French nuclear waste management situation and highlighted the significant French and EDF participation in RISCOM-II. He meant that the project should have possibilities to enhance transparency in nuclear waste programmes and noted that the new concept of stretching, introduced by RISCOM, is already is use. In the following the talks given at the workshop and the discussion that took place are summarized. Appendix 3 gives a brief overview of the RISCOM-II project

  17. Reflective Writing for Medical Students on the Surgical Clerkship: Oxymoron or Antidote?

    Science.gov (United States)

    Liu, Geoffrey Z; Jawitz, Oliver K; Zheng, Daniel; Gusberg, Richard J; Kim, Anthony W

    2016-01-01

    Reflective writing has emerged as a solution to declining empathy during clinical training. However, the role for reflective writing has not been studied in a surgical setting. The aim of this proof-of-concept study was to assess receptivity to a reflective-writing intervention among third-year medical students on their surgical clerkship. The reflective-writing intervention was a 1-hour, peer-facilitated writing workshop. This study employed a pre-post-intervention design. Subjects were surveyed on their experience 4 weeks before participation in the intervention and immediately afterwards. Surveys assessed student receptivity to reflective writing as well as self-perceived empathy, writing habits, and communication behaviors using a Likert-response scale. Quantitative responses were analyzed using paired t tests and linear regression. Qualitative responses were analyzed using an iterative consensus model. Yale-New Haven hospital, a tertiary care academic center. All medical students of Yale School of Medicine, rotating on their surgical clerkship during a 9-month period (74 in total) were eligible. In all, 25 students completed this study. The proportion of students desiring more opportunities for reflective writing increased from 32%-64%. The proportion of students receptive to a mandatory writing workshop increased from 16%-40%. These differences were both significant (p = 0.003 and p = 0.001). In all, 88% of students also reported new insight as a result of the workshop. In total, 39% of students reported a more positive impression of the surgical profession after participation. Overall, the workshop was well-received by students and improved student attitudes toward reflective writing and the surgical profession. Larger studies are required to validate the effect of this workshop on objective empathy measures. This study demonstrates how reflective writing can be incorporated into a presurgical curriculum. Copyright © 2015 Association of Program Directors in

  18. Pivotal response treatment for autism spectrum disorder: current perspectives

    Directory of Open Access Journals (Sweden)

    Lei J

    2017-06-01

    Full Text Available Jiedi Lei, Pamela Ventola Yale Child Study Center, Yale University School of Medicine, New Haven, CT, USA Abstract: Pivotal response treatment (PRT is an evidence-based behavioral intervention based on applied behavior analysis principles aimed to improve social communication skills in individuals with autism spectrum disorder (ASD. PRT adopts a more naturalistic approach and focuses on using a number of strategies to help increase children’s motivation during intervention. Since its conceptualization, PRT has received much empirical support for eliciting therapeutic gains in greater use of functional social communication skills in individuals with ASD. Building upon the empirical evidence supporting PRT, recent advancements have increasingly turned to using interdisciplinary research integrating neuroimaging techniques and behavioral measures to help identify objective biomarkers of treatment, which have two primary purposes. First, neuroimaging results can help characterize how PRT may elicit change, and facilitate partitioning of the heterogeneous profiles of neural mechanisms underlying similar profile of behavioral changes observed over PRT. Second, neuroimaging provides an objective means to both map and track how biomarkers may serve as reliable and sensitive predictors of responder profiles to PRT, assisting clinicians to identify who will most likely benefit from PRT. Together, a better understanding of both mechanisms of change and predictors of responder profile will help PRT to serve as a more precise and targeted intervention for individuals with ASD, thus moving towards the goal of precision medicine and improving quality of care. This review focuses on the recent emerging neuroimaging evidences supporting PRT, offering current perspectives on the importance of interdisciplinary research to help clinicians better understand how PRT works and predict who will respond to PRT. Keywords: PRT, ASD, biomarkers, neuroimaging

  19. PySeqLab: an open source Python package for sequence labeling and segmentation.

    Science.gov (United States)

    Allam, Ahmed; Krauthammer, Michael

    2017-11-01

    Text and genomic data are composed of sequential tokens, such as words and nucleotides that give rise to higher order syntactic constructs. In this work, we aim at providing a comprehensive Python library implementing conditional random fields (CRFs), a class of probabilistic graphical models, for robust prediction of these constructs from sequential data. Python Sequence Labeling (PySeqLab) is an open source package for performing supervised learning in structured prediction tasks. It implements CRFs models, that is discriminative models from (i) first-order to higher-order linear-chain CRFs, and from (ii) first-order to higher-order semi-Markov CRFs (semi-CRFs). Moreover, it provides multiple learning algorithms for estimating model parameters such as (i) stochastic gradient descent (SGD) and its multiple variations, (ii) structured perceptron with multiple averaging schemes supporting exact and inexact search using 'violation-fixing' framework, (iii) search-based probabilistic online learning algorithm (SAPO) and (iv) an interface for Broyden-Fletcher-Goldfarb-Shanno (BFGS) and the limited-memory BFGS algorithms. Viterbi and Viterbi A* are used for inference and decoding of sequences. Using PySeqLab, we built models (classifiers) and evaluated their performance in three different domains: (i) biomedical Natural language processing (NLP), (ii) predictive DNA sequence analysis and (iii) Human activity recognition (HAR). State-of-the-art performance comparable to machine-learning based systems was achieved in the three domains without feature engineering or the use of knowledge sources. PySeqLab is available through https://bitbucket.org/A_2/pyseqlab with tutorials and documentation. ahmed.allam@yale.edu or michael.krauthammer@yale.edu. Supplementary data are available at Bioinformatics online. © The Author 2017. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com

  20. An Epidemiologic Study on Ageing and Dysphagia in the Acute Care Geriatric-Hospitalized Population: A Replication and Continuation Study.

    Science.gov (United States)

    Leder, Steven B; Suiter, Debra M; Agogo, George O; Cooney, Leo M

    2016-10-01

    United States census data project dramatic increases in the geriatric population ageing demographics by 2060 with concomitant health-care consequences. The purpose of this replication and continuation study was to collect new 2014 demographic data relative to ageing, swallow evaluation referral rates, and oral feeding status in geriatric-hospitalized patients for comparison with published data from 2000 to 2007. This was a planned data acquisition study of consecutive hospitalized patients referred for swallow assessments. Swallow evaluation referral rates for 2014 were described according to inpatient discharges, age range 60-105 years grouped by decade, gender, admitting diagnostic category, results of swallow evaluations, and oral feeding status. Determination of aspiration risk status was made with the Yale Swallow Protocol and diagnosis of dysphagia made with fiberoptic endoscopic evaluation of swallowing (FEES). There were 1348 referrals and 961 patients ≥60 years of age participated. Overall swallow evaluation referral rates increased an average of 63 % between the comparison years 2007 and 2014 with consistent increases corresponding to the decades, i.e., 60-69 (46 %), 70-79 (68 %), 80-89 (53 %), and 90+ (222 %). A total of 75 % of participants resumed oral alimentation and oral medications. Swallow evaluation referral rates increased by 63 % for 60-90+ year-old acute care geriatric-hospitalized participants despite only a 23 % increase in inpatient discharges for the years 2007 versus 2014. This corroborated previously reported increases for individual years from 2000 to 2007. For timely, safe, and successful initiation of oral alimentation, it is important to perform a reliable swallow screen for aspiration risk assessment with the Yale Swallow Protocol and, if failed, instrumental testing with FEES. More dysphagia specialists are needed through 2060 and beyond due to projections of continued population ageing resulting in ever increasing

  1. Biodegradable micelles enhance the antiglioma activity of curcumin in vitro and in vivo

    Directory of Open Access Journals (Sweden)

    Zheng S

    2016-06-01

    Full Text Available Songping Zheng,1,* Xiang Gao,1,2,* Xiaoxiao Liu,1 Ting Yu,1 Tianying Zheng,1 Yi Wang,1 Chao You1 1Department of Neurosurgery, West China Hospital, West China Medical School, Sichuan University, Chengdu, People’s Republic of China; 2Department of Pharmacology, Yale School of Medicine, Yale University, New Haven, CT, USA *These authors contributed equally to this work Abstract: Curcumin (Cur, a natural polyphenol of Curcuma longa, has been recently reported to possess antitumor activities. However, due to its poor aqueous solubility and low biological availability, the clinical application of Cur is quite limited. The encapsulation of hydrophobic drugs into nanoparticles is an effective way to improve their pharmaceutical activities. In this research, nanomicelles loaded with Cur were formulated by a self-assembly method with biodegradable monomethoxy poly(ethylene glycol-poly(lactide copolymers (MPEG-PLAs. After encapsulation, the cellular uptake was increased and Cur could be released from MPEG-PLA micelles in a sustained manner. The Cur-loaded MPEG-PLA micelles (Cur/MPEG-PLA micelles exhibited an enhanced toxicity on C6 and U251 glioma cells and induced more apoptosis on C6 glioma cells compared with free Cur. Moreover, the therapy efficiency of Cur/MPEG-PLA micelles was evaluated at length on a nude mouse model bearing glioma. The Cur/MPEG-PLA micelles were more effective on suppressing tumor growth compared with free Cur, which indicated that Cur/MPEG-PLA micelles improved the antiglioma activity of Cur in vivo. The results of immunohistochemical and immunofluorescent analysis indicated that the induction of apoptosis, antiangiogenesis, and inhibition of cell proliferation may contribute to the improvement in antiglioma effects. Our data suggested that Cur/MPEG-PLA may have potential clinic applications in glioma therapy. Keywords: curcumin, glioma, cell apoptosis, cell proliferation, angiogenesis 

  2. Efficacy and Safety of Deep Brain Stimulation in Tourette Syndrome: The International Tourette Syndrome Deep Brain Stimulation Public Database and Registry.

    Science.gov (United States)

    Martinez-Ramirez, Daniel; Jimenez-Shahed, Joohi; Leckman, James Frederick; Porta, Mauro; Servello, Domenico; Meng, Fan-Gang; Kuhn, Jens; Huys, Daniel; Baldermann, Juan Carlos; Foltynie, Thomas; Hariz, Marwan I; Joyce, Eileen M; Zrinzo, Ludvic; Kefalopoulou, Zinovia; Silburn, Peter; Coyne, Terry; Mogilner, Alon Y; Pourfar, Michael H; Khandhar, Suketu M; Auyeung, Man; Ostrem, Jill Louise; Visser-Vandewalle, Veerle; Welter, Marie-Laure; Mallet, Luc; Karachi, Carine; Houeto, Jean Luc; Klassen, Bryan Timothy; Ackermans, Linda; Kaido, Takanobu; Temel, Yasin; Gross, Robert E; Walker, Harrison C; Lozano, Andres M; Walter, Benjamin L; Mari, Zoltan; Anderson, William S; Changizi, Barbara Kelly; Moro, Elena; Zauber, Sarah Elizabeth; Schrock, Lauren E; Zhang, Jian-Guo; Hu, Wei; Rizer, Kyle; Monari, Erin H; Foote, Kelly D; Malaty, Irene A; Deeb, Wissam; Gunduz, Aysegul; Okun, Michael S

    2018-03-01

    Collective evidence has strongly suggested that deep brain stimulation (DBS) is a promising therapy for Tourette syndrome. To assess the efficacy and safety of DBS in a multinational cohort of patients with Tourette syndrome. The prospective International Deep Brain Stimulation Database and Registry included 185 patients with medically refractory Tourette syndrome who underwent DBS implantation from January 1, 2012, to December 31, 2016, at 31 institutions in 10 countries worldwide. Patients with medically refractory symptoms received DBS implantation in the centromedian thalamic region (93 of 163 [57.1%]), the anterior globus pallidus internus (41 of 163 [25.2%]), the posterior globus pallidus internus (25 of 163 [15.3%]), and the anterior limb of the internal capsule (4 of 163 [2.5%]). Scores on the Yale Global Tic Severity Scale and adverse events. The International Deep Brain Stimulation Database and Registry enrolled 185 patients (of 171 with available data, 37 females and 134 males; mean [SD] age at surgery, 29.1 [10.8] years [range, 13-58 years]). Symptoms of obsessive-compulsive disorder were present in 97 of 151 patients (64.2%) and 32 of 148 (21.6%) had a history of self-injurious behavior. The mean (SD) total Yale Global Tic Severity Scale score improved from 75.01 (18.36) at baseline to 41.19 (20.00) at 1 year after DBS implantation (P tic subscore improved from 21.00 (3.72) at baseline to 12.91 (5.78) after 1 year (P tic subscore improved from 16.82 (6.56) at baseline to 9.63 (6.99) at 1 year (P Tourette syndrome but also with important adverse events. A publicly available website on outcomes of DBS in patients with Tourette syndrome has been provided.

  3. Premonitory Urges in Patients with Gilles de la Tourette Syndrome: An Italian Translation and a 7-Year Follow-up.

    Science.gov (United States)

    Gulisano, Mariangela; Calì, Paola; Palermo, Filippo; Robertson, Mary; Rizzo, Renata

    2015-12-01

    Premonitory sensations or urges (PUs) are described as characteristic sensory phenomena preceding tics, which are often described as unpleasant. They occur in 90% of patients affected by Gilles de la Tourette Syndrome (GTS). They may be localized (around the area of tic) or generalized (covering a wide area of the body). The PUs can be measured by the Premonitory Urge for Tics Scale (PUTS). In this study we translated the PUTS scale into Italian and then assessed children and adolescents/young people (CYP) with GTS using the scale. GTS patients were assessed at the initial interview and after 7 years to evaluate the PUs, and the correlations of the PUTS scores with tic severity, severity of comorbid disorders (obsessive-compulsive disorder [OCD], attention-deficit/hyperactivity disorder [ADHD]), and a variety of coexisting psychopathologies. A total of 95 patients were studied. We successfully translated the PUTS into Italian, and our results indicated that our translated version had good psychometric properties. Results demonstrated that the CYP had PUs at both interviews, but that older CYP were more consistent in reporting PUs than younger CYP (i.e., PUTS scores increased with age). We found no correlations between PUTS score and tic severity at either interview. We found a statistical significant correlation between PUTS score and obsessive-compulsive symptoms (OCS) at both interviews; Moreover both the PUTS and Children's Yale-Brown Obsessive Compulsive Scale (CY-BOCS) scores increased significantly, whereas the Yale Global Tic Severity Rating Scale (YGTSS) score decreased significantly. We found no relationships between PUTS scores and anxiety, depression, ADHD, and externalizing/internalizing behavioral scores. Our results suggest the the Italian translation of the PUTS has good psychometric properties. Although both younger (10 years of age, the PUs correlated with obsessions and compulsions (CY-BOCS scores).

  4. Abnormal topological organization in white matter structural networks revealed by diffusion tensor tractography in unmedicated patients with obsessive-compulsive disorder.

    Science.gov (United States)

    Zhong, Zhaoxi; Zhao, Tengda; Luo, Jia; Guo, Zhihua; Guo, Meng; Li, Ping; Sun, Jing; He, Yong; Li, Zhanjiang

    2014-06-03

    Obsessive-compulsive disorder (OCD) is a chronic psychiatric disorder defined by recurrent thoughts, intrusive and distressing impulses, or images and ritualistic behaviors. Although focal diverse regional abnormalities white matter integrity in specific brain regions have been widely studied in populations with OCD, alterations in the structural connectivities among them remain poorly understood. The aim was to investigate the abnormalities in the topological efficiency of the white matter networks and the correlation between the network metrics and Yale-Brown Obsessive-Compulsive Scale scores in unmedicated OCD patients, using diffusion tensor tractography and graph theoretical approaches. This study used diffusion tensor imaging and deterministic tractography to map the white matter structural networks in 26 OCD patients and 39 age- and gender-matched healthy controls; and then applied graph theoretical methods to investigate abnormalities in the global and regional properties of the white matter network in these patients. The patients and control participants both showed small-world organization of the white matter networks. However, the OCD patients exhibited significant abnormal global topology, including decreases in global efficiency (t = -2.32, p = 0.02) and increases in shortest path length, Lp (t = 2.30, p = 0.02), the normalized weighted shortest path length, λ (t = 2.08, p=0.04), and the normalized clustering coefficient, γ (t = 2.26, p = 0.03), of their white matter structural networks compared with healthy controls. Further, the OCD patients showed a reduction in nodal efficiency predominately in the frontal regions, the parietal regions and caudate nucleus. The normalized weighted shortest path length of the network metrics was significantly negatively correlated with obsessive subscale of the Yale-Brown Obsessive-Compulsive Scale (r = -0.57, p = 0.0058). These findings demonstrate the abnormal topological efficiency in the white matter networks

  5. An Ecometric Study of Recent Microfossils using High-throughput Imaging

    Science.gov (United States)

    Elder, L. E.; Hull, P. M.; Hsiang, A. Y.; Kahanamoku, S.

    2016-02-01

    The era of Big Data has ushered in the potential to collect population level information in a manageable time frame. Taxon-free morphological trait analysis, referred to as ecometrics, can be used to examine and compare ecological dynamics between communities with entirely different species compositions. Until recently population level studies of morphology were difficult because of the time intensive task of collecting measurements. To overcome this, we implemented advances in imaging technology and created software to automate measurements. This high-throughput set of methods collects assemblage-scale data, with methods tuned to foraminiferal samples (e.g., light objects on a dark background). Methods include serial focused dark-field microscopy, custom software (Automorph) to batch process images, extract 2D and 3D shape parameters and frames, and implement landmark-free geometric morphometric analyses. Informatics pipelines were created to store, catalog and share images through the Yale Peabody Museum(YPM; peabody.yale.edu). We openly share software and images to enhance future data discovery. In less than a year we have generated over 25TB of high resolution semi 3D images for this initial study. Here, we take the first step towards developing ecometric approaches for open ocean microfossil communities with a calibration study of community shape in recent sediments. We will present an overview of the `shape' of modern planktonic foraminiferal communities from 25 Atlantic core top samples (23 sites in the North and Equatorial Atlantic; 2 sites in the South Atlantic). In total, more than 100,000 microfossils and fragments were imaged from these sites' sediment cores, an unprecedented morphometric sample set. Correlates of community shape, including diversity, temperature, and latitude, will be discussed. These methods have also been applied to images of limpets and fish teeth to date, and have the potential to be used on modern taxa to extract meaningful

  6. Comparative Simulation Study of Glucose Control Methods Designed for Use in the Intensive Care Unit Setting via a Novel Controller Scoring Metric.

    Science.gov (United States)

    DeJournett, Jeremy; DeJournett, Leon

    2017-11-01

    Effective glucose control in the intensive care unit (ICU) setting has the potential to decrease morbidity and mortality rates and thereby decrease health care expenditures. To evaluate what constitutes effective glucose control, typically several metrics are reported, including time in range, time in mild and severe hypoglycemia, coefficient of variation, and others. To date, there is no one metric that combines all of these individual metrics to give a number indicative of overall performance. We proposed a composite metric that combines 5 commonly reported metrics, and we used this composite metric to compare 6 glucose controllers. We evaluated the following controllers: Ideal Medical Technologies (IMT) artificial-intelligence-based controller, Yale protocol, Glucommander, Wintergerst et al PID controller, GRIP, and NICE-SUGAR. We evaluated each controller across 80 simulated patients, 4 clinically relevant exogenous dextrose infusions, and one nonclinical infusion as a test of the controller's ability to handle difficult situations. This gave a total of 2400 5-day simulations, and 585 604 individual glucose values for analysis. We used a random walk sensor error model that gave a 10% MARD. For each controller, we calculated severe hypoglycemia (140 mg/dL), and coefficient of variation (CV), as well as our novel controller metric. For the controllers tested, we achieved the following median values for our novel controller scoring metric: IMT: 88.1, YALE: 46.7, GLUC: 47.2, PID: 50, GRIP: 48.2, NICE: 46.4. The novel scoring metric employed in this study shows promise as a means for evaluating new and existing ICU-based glucose controllers, and it could be used in the future to compare results of glucose control studies in critical care. The IMT AI-based glucose controller demonstrated the most consistent performance results based on this new metric.

  7. Use of mobile low-bandwith telemedical techniques for extreme telemedicine applications.

    Science.gov (United States)

    Rosser, J C; Bell, R L; Harnett, B; Rodas, E; Murayama, M; Merrell, R

    1999-10-01

    Telemedicine is traditionally associated with the use of very expensive and bulky telecommunications equipment along with substantial bandwidth requirements (128 kilobytes per second [kbps] or greater). Telementoring is an educational technique that involves real-time guidance of a less experienced physician through a procedure in which he or she has limited experience. This technique has been especially dependent on the aforementioned requirements. Traditionally, telemedicine and telementoring have been restricted to technically sophisticated sites. The telemedicine applications through the existing telecommunication infrastructure has not been possible for underdeveloped parts of the world. Telemedicine and telementoring were applied using low-bandwidth mobile telemedicine applications to support a mobile surgery program in rural Ecuador run by the Cinterandes Foundation and headed by Edgar Rodas, MD. A mobile operating room traveled to a remote region of Ecuador. Using a laptop computer equipped with telemedicine software, a videoconferencing system, and a digital camera, surgical patients were evaluated and operative decisions were made over low-bandwidth telephone lines. Similarly, surgeons in the mobile unit in Ecuador were telementored by an experienced surgeon located thousands of miles away at Yale University School of Medicine. Five preoperative evaluations were conducted from Sucua to Cuenca, Ecuador, with excellent clinical correlation. Additionally, a laparoscopic cholecystectomy was successfully telementored from the department of surgery at Yale University School of Medicine to the mobile surgery unit in Ecuador. The telementored surgery was performed using a telephone line with a baud rate of 12 kbps. Mobile, low-bandwidth telemedicine applications used in the proper technical and clinical algorithms can be very effective in supporting remote health care delivery efforts. Advantages of such applications include increased cost-effectiveness by

  8. Behavior therapy for children with Tourette disorder: a randomized controlled trial.

    Science.gov (United States)

    Piacentini, John; Woods, Douglas W; Scahill, Lawrence; Wilhelm, Sabine; Peterson, Alan L; Chang, Susanna; Ginsburg, Golda S; Deckersbach, Thilo; Dziura, James; Levi-Pearl, Sue; Walkup, John T

    2010-05-19

    Tourette disorder is a chronic and typically impairing childhood-onset neurologic condition. Antipsychotic medications, the first-line treatments for moderate to severe tics, are often associated with adverse effects. Behavioral interventions, although promising, have not been evaluated in large-scale controlled trials. To determine the efficacy of a comprehensive behavioral intervention for reducing tic severity in children and adolescents. Randomized, observer-blind, controlled trial of 126 children recruited from December 2004 through May 2007 and aged 9 through 17 years, with impairing Tourette or chronic tic disorder as a primary diagnosis, randomly assigned to 8 sessions during 10 weeks of behavior therapy (n = 61) or a control treatment consisting of supportive therapy and education (n = 65). Responders received 3 monthly booster treatment sessions and were reassessed at 3 and 6 months following treatment. Comprehensive behavioral intervention. Yale Global Tic Severity Scale (range 0-50, score >15 indicating clinically significant tics) and Clinical Global Impressions-Improvement Scale (range 1 [very much improved] to 8 [very much worse]). Behavioral intervention led to a significantly greater decrease on the Yale Global Tic Severity Scale (24.7 [95% confidence interval {CI}, 23.1-26.3] to 17.1 [95% CI, 15.1-19.1]) from baseline to end point compared with the control treatment (24.6 [95% CI, 23.2-26.0] to 21.1 [95% CI, 19.2-23.0]) (P tic worsening was reported by 4% of children (5/126). Treatment gains were durable, with 87% of available responders to behavior therapy exhibiting continued benefit 6 months following treatment. A comprehensive behavioral intervention, compared with supportive therapy and education, resulted in greater improvement in symptom severity among children with Tourette and chronic tic disorder. clinicaltrials.gov Identifier: NCT00218777.

  9. A conversation with Paul Greengard. Interview by Eric J Nestler.

    Science.gov (United States)

    Greengard, Paul

    2013-01-01

    Paul Greengard was born in New York City in 1925. After completing high school, he served three years in the US Navy during World War II and then completed his bachelor's degree at Hamilton College where he majored in physics and mathematics. He obtained a PhD in biophysics from Johns Hopkins University in 1953 and pursued postdoctoral training with Wilhelm Feldberg at the National Institute for Medical Research in England. After eight years as head of biochemistry at Geigy, and sabbaticals at Albert Einstein College of Medicine and Vanderbilt University, he joined the Yale University faculty as a full professor of pharmacology in 1968. While he was at Yale, Greengard's laboratory performed groundbreaking research, which demonstrated a role for cyclic nucleotides, protein kinases and protein phosphatases, and their protein substrates in the regulation of synaptic transmission. In 1983, Greengard moved to The Rockefeller University, where he has since served as the Vincent Astor Professor and Head of the Laboratory of Molecular and Cellular Neuroscience. Greengard's paradigm-shifting research has continued at Rockefeller and has informed our understanding and possible treatment of a host of brain disorders, including schizophrenia, Alzheimer's disease, Parkinson's disease, and depression. He is the author of more than 950 research articles and reviews. Greengard has received numerous awards and honors, including the Nobel Prize in Physiology or Medicine in 2000, the Metropolitan Life Foundation Award for Medical Research, The National Academy of Sciences Award in Neuroscience, the Ralph W. Gerard Prize in Neuroscience for the Society for Neuroscience, and the Karolinska Institutet's Bicentennial Gold Medal. He is a member of the US National Academy of Sciences and the Institute of Medicine of the National Academies. The following interview was conducted on May 29, 2012.

  10. Sphere of influence

    Science.gov (United States)

    After years of New Age celebrity, the Biosphere 2 project is officially going legit. As part of a five-year management agreement, the staff of Columbia University's Lamont-Doherty Earth Observatory will oversee the research, as well as the educational projects and tourism operations, of the enclosed prototype of Earth situated in the Arizona desert. A consortium of scientists from Harvard, Columbia, Stanford, Yale, the Smithsonian Institutions, the Australian National University, and several other institutions has already set about designing experiments in biogeochemistry, sustainable agriculture, climate change, biodiversity, and ecology. Plans also are being made to turn Biosphere 2 into a “science education center devoted exclusively to how the world works.”

  11. Uniform design based SVM model selection for face recognition

    Science.gov (United States)

    Li, Weihong; Liu, Lijuan; Gong, Weiguo

    2010-02-01

    Support vector machine (SVM) has been proved to be a powerful tool for face recognition. The generalization capacity of SVM depends on the model with optimal hyperparameters. The computational cost of SVM model selection results in application difficulty in face recognition. In order to overcome the shortcoming, we utilize the advantage of uniform design--space filling designs and uniformly scattering theory to seek for optimal SVM hyperparameters. Then we propose a face recognition scheme based on SVM with optimal model which obtained by replacing the grid and gradient-based method with uniform design. The experimental results on Yale and PIE face databases show that the proposed method significantly improves the efficiency of SVM model selection.

  12. Identifying Jets Using Artifical Neural Networks

    Science.gov (United States)

    Rosand, Benjamin; Caines, Helen; Checa, Sofia

    2017-09-01

    We investigate particle jet interactions with the Quark Gluon Plasma (QGP) using artificial neural networks modeled on those used in computer image recognition. We create jet images by binning jet particles into pixels and preprocessing every image. We analyzed the jets with a Multi-layered maxout network and a convolutional network. We demonstrate each network's effectiveness in differentiating simulated quenched jets from unquenched jets, and we investigate the method that the network uses to discriminate among different quenched jet simulations. Finally, we develop a greater understanding of the physics behind quenched jets by investigating what the network learnt as well as its effectiveness in differentiating samples. Yale College Freshman Summer Research Fellowship in the Sciences and Engineering.

  13. Experiments around I-8

    CERN Multimedia

    CERN PhotoLab

    1975-01-01

    The lithium transition-radiation detectors and the large liquid argon calorimeters of experiment R806T are shown above and below the intersection at I-8 (Brookhaven-CERN-Saclay-Syracuse-Yale Collaboration, Study of large transverse momentum phenomena by electron and photon detection). At 90 deg to the intersecting beams are the monitoring proporional chambers of experiment R805 (Measurement of real to imaginary ratio of forward scattering amplitude - Coulomb interference - by the CERN-Rome Collaboration). Left and right of the intersection one sees, symmetrically placed around the interaction region, the large scintillation counters hodoscopes used by R801 (Pisa-Stony Brook Collaboration) to measure the pp total cross section and the features of inelastic collisions.

  14. Face recognition by combining eigenface method with different wavelet subbands

    Institute of Scientific and Technical Information of China (English)

    MA Yan; LI Shun-bao

    2006-01-01

    @@ A method combining eigenface with different wavelet subbands for face recognition is proposed.Each training image is decomposed into multi-subbands for extracting their eigenvector sets and projection vectors.In the recognition process,the inner product distance between the projection vectors of the test image and that of the training image are calculated.The training image,corresponding to the maximum distance under the given threshold condition,is considered as the final result.The experimental results on the ORL and YALE face database show that,compared with the eigenface method directly on the image domain or on a single wavelet subband,the recognition accuracy using the proposed method is improved by 5% without influencing the recognition speed.

  15. Close visual binaries. III. Parameters and evolutionary status

    International Nuclear Information System (INIS)

    Corbally, C.J.

    1984-01-01

    New Yale isochrones, which have been tested for accuracy (Paper II), provide the means to investigate interesting visual binaries, especially those whose classifications and photometry do not match well (Paper I). Various parameters are deduced for those binaries which fitted the isochrones (e.g., ages, metal abundances, luminosities of peculiar stars); various solutions are systematically developed for those which did not fit, and a likely status of evolution proposed (e.g., duplicity of the components, pre-main-sequence, blue straggler, horizontal branch, optical pair, data inaccuracies). Evolution around the helium flash and diffusion theory are briefly considered. These parameters and statuses provide a wealth of new stellar data and suggestions for further investigation

  16. Close visual binaries. III. Parameters and evolutionary status

    Energy Technology Data Exchange (ETDEWEB)

    Corbally, C.J.

    1984-12-01

    New Yale isochrones, which have been tested for accuracy (Paper II), provide the means to investigate interesting visual binaries, especially those whose classifications and photometry do not match well (Paper I). Various parameters are deduced for those binaries which fitted the isochrones (e.g., ages, metal abundances, luminosities of peculiar stars); various solutions are systematically developed for those which did not fit, and a likely status of evolution proposed (e.g., duplicity of the components, pre-main-sequence, blue straggler, horizontal branch, optical pair, data inaccuracies). Evolution around the helium flash and diffusion theory are briefly considered. These parameters and statuses provide a wealth of new stellar data and suggestions for further investigation.

  17. Conjugation in Escherichia coli

    Science.gov (United States)

    Boyer, Herbert

    1966-01-01

    Boyer, Herbert (Yale University, New Haven, Conn.). Conjugation in Escherichia coli. J. Bacteriol. 91:1767–1772. 1966.—The sex factor of Escherichia coli K-12 was introduced into an E. coli B/r strain by circumventing the host-controlled modification and restriction incompatibilities known to exist between these closely related strains. The sexual properties of the constructed F+ B strain and its Hfr derivatives were examined. These studies showed that the E. coli strain B/r F+ and Hfr derivatives are similar to the E. coli strain K-12 F+ and Hfr derivatives. However, the site of sex factor integration was found to be dependent on the host genome. PMID:5327905

  18. B(M1) values in the band-crossing of shears bands in 197Pb

    Science.gov (United States)

    Krücken, R.; Cooper, J. R.; Beausang, C. W.; Novak, J. R.; Dewald, A.; Klug, T.; Kemper, G.; von Brentano, P.; Carpenter, M.; Wiedenhöver, I.

    We present details of the band crossing mechanism of shears bands using the example of 197Pb. Absolute reduced matrix elements B(M1) were determined by means of a RDM lifetime measurement in one of the shears bands in 197Pb. The experiment was performed using the New Yale Plunger Device (NYPD) in conjunction with the Gammasphere array. Band mixing calculations on the basis of the semi-classical model of the shears mechanism are used to describe the transition matrix elements B(M1) and energies throughout the band-crossing regions. Good agreement with the data was obtained and the detailed composition of the states in the shears band are discussed.

  19. Chernobyl: the final warning

    International Nuclear Information System (INIS)

    Gale, R.P.; Hauser, Thomas.

    1988-01-01

    Following the Chernobyl accident in 1986, a book has been written with firstly an introduction to the basic principles and development of nuclear power, followed by a brief review of previous nuclear power plant accidents and then a short account of the Chernobyl accident itself. The main text of the book however contains the personal story of Dr. Robert Peter Yale, head of the Bone Marrow Transplant Unit at the UCLA Medical Center in Los Angeles who travelled to Russia six times to help the victims of the Chernobyl accident. The final part of the book discusses the safety of nuclear power and the dangers of the proliferation of nuclear weapons. (U.K.)

  20. Fever, petechiae, and pulmonary infiltrates in an immunocompromised Peruvian man.

    Science.gov (United States)

    Berenson, C. S.; Dobuler, K. J.; Bia, F. J.

    1987-01-01

    The diagnostic considerations raised by immunocompromised patients with opportunistic infection continue to expand. When such patients harbor latent or persistent infection acquired in a tropical environment, the diagnostic challenge is even greater. The Infectious Disease Service at Yale-New Haven Hospital was asked to see a middle-aged man from Peru with known T-cell lymphoma who had recently completed a course of chemotherapy. He presented to the hospital with fever, petechial skin rash, pulmonary infiltrates, and neutropenia. Ultimately this case illustrated the necessity for careful evaluation of such patients, looking, in particular, for evidence of opportunistic parasitic infection. Images FIG. 1 FIG. 2 FIG. 3 FIG. 4 FIG. 5 PMID:3424876