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Sample records for thermal stress adaptation

  1. Adaptive Responses to Thermal Stress in Mammals

    Directory of Open Access Journals (Sweden)

    Yasser Lenis Sanin

    2015-12-01

    Full Text Available The environment animals have to cope with is a combination of natural factors such as temperature. Extreme changes in these factors can alter homeostasis, which can lead to thermal stress. This stress can be due to either high temperatures or low temperatures. Energy transference for thermoregulation in homoeothermic animals occurs through several mechanisms: conduction, convection, radiation and evaporation. When animals are subjected to thermal stress, physiological mechanisms are activated which may include endocrine, neuroendocrine and behavioral responses. Activation of the neuroendocrine system affects the secretion of hormones and neurotransmitters which act collectively as response mechanisms that allow them to adapt to stress. Mechanisms which have developed through evolution to allow animals to adapt to high environmental temperatures and to achieve thermo tolerance include physiological and physical changes in order to reduce food intake and metabolic heat production, to increase surface area of skin to dissipate heat, to increase blood flow to take heat from the body core to the skin and extremities to dissipate the heat, to increase numbers and activity of sweat glands, panting, water intake and color adaptation of integument system to reflect heat. Chronic exposure to thermal stress can cause disease, reduce growth, decrease productive and reproductive performance and, in extreme cases, lead to death. This paper aims to briefly explain the physical and physiological responses of mammals to thermal stress, like a tool for biological environment adaptation, emphasizing knowledge gaps and offering some recommendations to stress control for the animal production system.

  2. Adaptive Responses to Thermal Stress in Mammals

    OpenAIRE

    Yasser Lenis Sanin; Angélica María Zuluaga Cabrera; Ariel Marcel Tarazona Morales

    2015-01-01

    The environment animals have to cope with is a combination of natural factors such as temperature. Extreme changes in these factors can alter homeostasis, which can lead to thermal stress. This stress can be due to either high temperatures or low temperatures. Energy transference for thermoregulation in homoeothermic animals occurs through several mechanisms: conduction, convection, radiation and evaporation. When animals are subjected to thermal stress, physiological mechanisms are activated...

  3. Contrasting Patterns of Coral Bleaching Susceptibility in 2010 Suggest an Adaptive Response to Thermal Stress

    Science.gov (United States)

    Guest, James R.; Baird, Andrew H.; Maynard, Jeffrey A.; Muttaqin, Efin; Edwards, Alasdair J.; Campbell, Stuart J.; Yewdall, Katie; Affendi, Yang Amri; Chou, Loke Ming

    2012-01-01

    Background Coral bleaching events vary in severity, however, to date, the hierarchy of susceptibility to bleaching among coral taxa has been consistent over a broad geographic range and among bleaching episodes. Here we examine the extent of spatial and temporal variation in thermal tolerance among scleractinian coral taxa and between locations during the 2010 thermally induced, large-scale bleaching event in South East Asia. Methodology/Principal Findings Surveys to estimate the bleaching and mortality indices of coral genera were carried out at three locations with contrasting thermal and bleaching histories. Despite the magnitude of thermal stress being similar among locations in 2010, there was a remarkable contrast in the patterns of bleaching susceptibility. Comparisons of bleaching susceptibility within coral taxa and among locations revealed no significant differences between locations with similar thermal histories, but significant differences between locations with contrasting thermal histories (Friedman = 34.97; pSingapore, where only 5% and 12% of colonies died. Conclusions/Significance The pattern of susceptibility among coral genera documented here is unprecedented. A parsimonious explanation for these results is that coral populations that bleached during the last major warming event in 1998 have adapted and/or acclimatised to thermal stress. These data also lend support to the hypothesis that corals in regions subject to more variable temperature regimes are more resistant to thermal stress than those in less variable environments. PMID:22428027

  4. Thermal Stress Limit Rafting Migration of Seahorses: Prediction Based on Physiological and Behavioral Responses to Thermal Stress

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    Qin, G.; Li, C.; Lin, Q.

    2017-12-01

    Marine fish species escape from harmful environment by migration. Seahorses, with upright posture and low mobility, could migrate from unfavorable environment by rafting with their prehensile tail. The present study was designed to examine the tolerance of lined seahorse Hippocampus erectus to thermal stress and evaluate the effects of temperature on seahorse migration. The results figured that seahorses' tolerance to thermal stress was time dependent. Acute thermal stress (30°C) increased breathing rate and HSP genes expression significantly, but didn't affect seahorse feeding behavior. Chronic thermal treatment lead to persistent high expression of HSP genes, higher breathing rate, and decreasing feeding, and final higher mortality, suggesting that seahorse cannot adapt to thermal stress by acclimation. No significant negative effects were found in seahorse reproduction in response to chronic thermal stress. Given that seahorses make much slower migration by rafting on sea surface compared to other fishes, we suggest that thermal stress might limit seahorse migration range. and the influence might be magnified by global warming in future.

  5. Contrasting patterns of coral bleaching susceptibility in 2010 suggest an adaptive response to thermal stress.

    Science.gov (United States)

    Guest, James R; Baird, Andrew H; Maynard, Jeffrey A; Muttaqin, Efin; Edwards, Alasdair J; Campbell, Stuart J; Yewdall, Katie; Affendi, Yang Amri; Chou, Loke Ming

    2012-01-01

    Coral bleaching events vary in severity, however, to date, the hierarchy of susceptibility to bleaching among coral taxa has been consistent over a broad geographic range and among bleaching episodes. Here we examine the extent of spatial and temporal variation in thermal tolerance among scleractinian coral taxa and between locations during the 2010 thermally induced, large-scale bleaching event in South East Asia. Surveys to estimate the bleaching and mortality indices of coral genera were carried out at three locations with contrasting thermal and bleaching histories. Despite the magnitude of thermal stress being similar among locations in 2010, there was a remarkable contrast in the patterns of bleaching susceptibility. Comparisons of bleaching susceptibility within coral taxa and among locations revealed no significant differences between locations with similar thermal histories, but significant differences between locations with contrasting thermal histories (Friedman = 34.97; pBleaching was much less severe at locations that bleached during 1998, that had greater historical temperature variability and lower rates of warming. Remarkably, Acropora and Pocillopora, taxa that are typically highly susceptible, although among the most susceptible in Pulau Weh (Sumatra, Indonesia) where respectively, 94% and 87% of colonies died, were among the least susceptible in Singapore, where only 5% and 12% of colonies died. The pattern of susceptibility among coral genera documented here is unprecedented. A parsimonious explanation for these results is that coral populations that bleached during the last major warming event in 1998 have adapted and/or acclimatised to thermal stress. These data also lend support to the hypothesis that corals in regions subject to more variable temperature regimes are more resistant to thermal stress than those in less variable environments.

  6. A candidate multimodal functional genetic network for thermal adaptation

    Directory of Open Access Journals (Sweden)

    Katharina C. Wollenberg Valero

    2014-09-01

    Full Text Available Vertebrate ectotherms such as reptiles provide ideal organisms for the study of adaptation to environmental thermal change. Comparative genomic and exomic studies can recover markers that diverge between warm and cold adapted lineages, but the genes that are functionally related to thermal adaptation may be difficult to identify. We here used a bioinformatics genome-mining approach to predict and identify functions for suitable candidate markers for thermal adaptation in the chicken. We first established a framework of candidate functions for such markers, and then compiled the literature on genes known to adapt to the thermal environment in different lineages of vertebrates. We then identified them in the genomes of human, chicken, and the lizard Anolis carolinensis, and established a functional genetic interaction network in the chicken. Surprisingly, markers initially identified from diverse lineages of vertebrates such as human and fish were all in close functional relationship with each other and more associated than expected by chance. This indicates that the general genetic functional network for thermoregulation and/or thermal adaptation to the environment might be regulated via similar evolutionarily conserved pathways in different vertebrate lineages. We were able to identify seven functions that were statistically overrepresented in this network, corresponding to four of our originally predicted functions plus three unpredicted functions. We describe this network as multimodal: central regulator genes with the function of relaying thermal signal (1, affect genes with different cellular functions, namely (2 lipoprotein metabolism, (3 membrane channels, (4 stress response, (5 response to oxidative stress, (6 muscle contraction and relaxation, and (7 vasodilation, vasoconstriction and regulation of blood pressure. This network constitutes a novel resource for the study of thermal adaptation in the closely related nonavian reptiles and

  7. Dispersal, behavioral responses and thermal adaptation in Musca domestica

    DEFF Research Database (Denmark)

    Kjaersgaard, Anders; Blackenhorn, Wolf U.; Pertoldi, Cino

    were obtained with flies held for several generations in a laboratory common garden setting, therefore we suggest that exposure to and avoidance of high temperatures under natural conditions has been an important selective agent causing the suggested adaptive differentiation between the populations.......Behavioral traits can have great impact on an organism’s ability to cope with or avoidance of thermal stress, and are therefore of evolutionary importance for thermal adaptation. We compared the morphology, heat resistance, locomotor (walking and flying) activity and flight performance of three...

  8. Reef calcifiers are adapted to episodic heat stress but vulnerable to sustained warming.

    Science.gov (United States)

    Stuhr, Marleen; Reymond, Claire E; Rieder, Vera; Hallock, Pamela; Rahnenführer, Jörg; Westphal, Hildegard; Kucera, Michal

    2017-01-01

    Shallow marine ecosystems naturally experience fluctuating physicochemical conditions across spatial and temporal scales. Widespread coral-bleaching events, induced by prolonged heat stress, highlight the importance of how the duration and frequency of thermal stress influence the adaptive physiology of photosymbiotic calcifiers. Large benthic foraminifera harboring algal endosymbionts are major tropical carbonate producers and bioindicators of ecosystem health. Like corals, they are sensitive to thermal stress and bleach at temperatures temporarily occurring in their natural habitat and projected to happen more frequently. However, their thermal tolerance has been studied so far only by chronic exposure, so how they respond under more realistic episodic heat-event scenarios remains unknown. Here, we determined the physiological responses of Amphistegina gibbosa, an abundant western Atlantic foraminifera, to four different treatments--control, single, episodic, and chronic exposure to the same thermal stress (32°C)--in controlled laboratory cultures. Exposure to chronic thermal stress reduced motility and growth, while antioxidant capacity was elevated, and photosymbiont variables (coloration, oxygen-production rates, chlorophyll a concentration) indicated extensive bleaching. In contrast, single- and episodic-stress treatments were associated with higher motility and growth, while photosymbiont variables remained stable. The effects of single and episodic heat events were similar, except for the presumable occurrence of reproduction, which seemed to be suppressed by both episodic and chronic stress. The otherwise different responses between treatments with thermal fluctuations and chronic stress indicate adaptation to thermal peaks, but not to chronic exposure expected to ensue when baseline temperatures are elevated by climate change. This firstly implies that marine habitats with a history of fluctuating thermal stress potentially support resilient

  9. Investigating the molecular basis of local adaptation to thermal stress: population differences in gene expression across the transcriptome of the copepod Tigriopus californicus

    Directory of Open Access Journals (Sweden)

    Schoville Sean D

    2012-09-01

    Full Text Available Abstract Background Geographic variation in the thermal environment impacts a broad range of biochemical and physiological processes and can be a major selective force leading to local population adaptation. In the intertidal copepod Tigriopus californicus, populations along the coast of California show differences in thermal tolerance that are consistent with adaptation, i.e., southern populations withstand thermal stresses that are lethal to northern populations. To understand the genetic basis of these physiological differences, we use an RNA-seq approach to compare genome-wide patterns of gene expression in two populations known to differ in thermal tolerance. Results Observed differences in gene expression between the southern (San Diego and the northern (Santa Cruz populations included both the number of affected loci as well as the identity of these loci. However, the most pronounced differences concerned the amplitude of up-regulation of genes producing heat shock proteins (Hsps and genes involved in ubiquitination and proteolysis. Among the hsp genes, orthologous pairs show markedly different thermal responses as the amplitude of hsp response was greatly elevated in the San Diego population, most notably in members of the hsp70 gene family. There was no evidence of accelerated evolution at the sequence level for hsp genes. Among other sets of genes, cuticle genes were up-regulated in SD but down-regulated in SC, and mitochondrial genes were down-regulated in both populations. Conclusions Marked changes in gene expression were observed in response to acute sub-lethal thermal stress in the copepod T. californicus. Although some qualitative differences were observed between populations, the most pronounced differences involved the magnitude of induction of numerous hsp and ubiquitin genes. These differences in gene expression suggest that evolutionary divergence in the regulatory pathway(s involved in acute temperature stress may offer at

  10. Oxidative stress adaptation with acute, chronic, and repeated stress.

    Science.gov (United States)

    Pickering, Andrew M; Vojtovich, Lesya; Tower, John; A Davies, Kelvin J

    2013-02-01

    Oxidative stress adaptation, or hormesis, is an important mechanism by which cells and organisms respond to, and cope with, environmental and physiological shifts in the level of oxidative stress. Most studies of oxidative stress adaption have been limited to adaptation induced by acute stress. In contrast, many if not most environmental and physiological stresses are either repeated or chronic. In this study we find that both cultured mammalian cells and the fruit fly Drosophila melanogaster are capable of adapting to chronic or repeated stress by upregulating protective systems, such as their proteasomal proteolytic capacity to remove oxidized proteins. Repeated stress adaptation resulted in significant extension of adaptive responses. Repeated stresses must occur at sufficiently long intervals, however (12-h or more for MEF cells and 7 days or more for flies), for adaptation to be successful, and the levels of both repeated and chronic stress must be lower than is optimal for adaptation to acute stress. Regrettably, regimens of adaptation to both repeated and chronic stress that were successful for short-term survival in Drosophila nevertheless also caused significant reductions in life span for the flies. Thus, although both repeated and chronic stress can be tolerated, they may result in a shorter life. Copyright © 2012 Elsevier Inc. All rights reserved.

  11. Gene Expression Dynamics Accompanying the Sponge Thermal Stress Response.

    Science.gov (United States)

    Guzman, Christine; Conaco, Cecilia

    2016-01-01

    Marine sponges are important members of coral reef ecosystems. Thus, their responses to changes in ocean chemistry and environmental conditions, particularly to higher seawater temperatures, will have potential impacts on the future of these reefs. To better understand the sponge thermal stress response, we investigated gene expression dynamics in the shallow water sponge, Haliclona tubifera (order Haplosclerida, class Demospongiae), subjected to elevated temperature. Using high-throughput transcriptome sequencing, we show that these conditions result in the activation of various processes that interact to maintain cellular homeostasis. Short-term thermal stress resulted in the induction of heat shock proteins, antioxidants, and genes involved in signal transduction and innate immunity pathways. Prolonged exposure to thermal stress affected the expression of genes involved in cellular damage repair, apoptosis, signaling and transcription. Interestingly, exposure to sublethal temperatures may improve the ability of the sponge to mitigate cellular damage under more extreme stress conditions. These insights into the potential mechanisms of adaptation and resilience of sponges contribute to a better understanding of sponge conservation status and the prediction of ecosystem trajectories under future climate conditions.

  12. Molecular evolution and thermal adaptation

    Science.gov (United States)

    Chen, Peiqiu

    2011-12-01

    In this thesis, we address problems in molecular evolution, thermal adaptation, and the kinetics of adaptation of bacteria and viruses to elevated environmental temperatures. We use a nearly neutral fitness model where the replication speed of an organism is proportional to the copy number of folded proteins. Our model reproduces the distribution of stabilities of natural proteins in excellent agreement with experiment. We find that species with high mutation rates tend to have less stable proteins compared to species with low mutation rate. We found that a broad distribution of protein stabilities observed in the model and in experiment is the key determinant of thermal response for viruses and bacteria. Our results explain most of the earlier experimental observations: striking asymmetry of thermal response curves, the absence of evolutionary trade-off which was expected but not found in experiments, correlation between denaturation temperature for several protein families and the Optimal Growth Temperature (OGT) of their carrier organisms, and proximity of bacterial or viral OGTs to their evolutionary temperatures. Our theory quantitatively and with high accuracy described thermal response curves for 35 bacterial species. The model also addresses the key to adaptation is in weak-link genes (WLG), which encode least thermodynamically stable essential proteins in the proteome. We observe, as in experiment, a two-stage adaptation process. The first stage is a Luria-Delbruck type of selection, whereby rare WLG alleles, whose proteins are more stable than WLG proteins of the majority of the population (either due to standing genetic variation or due to an early acquired mutation), rapidly rise to fixation. The second stage constitutes subsequent slow accumulation of mutations in an adapted population. As adaptation progresses, selection regime changes from positive to neutral: Selection coefficient of beneficial mutations scales as a negative power of number of

  13. Thermal stress mitigation by Active Thermal Control

    DEFF Research Database (Denmark)

    Soldati, Alessandro; Dossena, Fabrizio; Pietrini, Giorgio

    2017-01-01

    This work proposes an Active Thermal Control (ATC) of power switches. Leveraging on the fact that thermal stress has wide impact on the system reliability, controlling thermal transients is supposed to lengthen the lifetime of electronic conversion systems. Indeed in some environments...... results of control schemes are presented, together with evaluation of the proposed loss models. Experimental proof of the ability of the proposed control to reduce thermal swing and related stress on the device is presented, too....

  14. Heat stress mortality and desired adaptation responses of healthcare system in Poland

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    Błażejczyk, Anna; Błażejczyk, Krzysztof; Baranowski, Jarosław; Kuchcik, Magdalena

    2018-03-01

    Heat stress is one of the environmental factors influencing the health of individuals and the wider population. There is a large body of research to document significant increases in mortality and morbidity during heat waves all over the world. This paper presents key results of research dealing with heat-related mortality (HRM) in various cities in Poland which cover about 25% of the country's population. Daily mortality and weather data reports for the years 1991-2000 were used. The intensity of heat stress was assessed by the universal thermal climate index (UTCI). The research considers also the projections of future bioclimate to the end of twenty-first century. Brain storming discussions were applied to find necessary adaptation strategies of healthcare system (HCS) in Poland, to minimise negative effects of heat stress. In general, in days with strong and very strong heat stress, ones must expect increase in mortality (in relation to no thermal stress days) of 12 and 47%, respectively. Because of projected rise in global temperature and heat stress frequency, we must expect significant increase in HRM to the end of twenty-first century of even 165% in comparison to present days. The results of research show necessity of urgent implementation of adaptation strategies to heat in HCS.

  15. Symbiosis-induced adaptation to oxidative stress.

    Science.gov (United States)

    Richier, Sophie; Furla, Paola; Plantivaux, Amandine; Merle, Pierre-Laurent; Allemand, Denis

    2005-01-01

    Cnidarians in symbiosis with photosynthetic protists must withstand daily hyperoxic/anoxic transitions within their host cells. Comparative studies between symbiotic (Anemonia viridis) and non-symbiotic (Actinia schmidti) sea anemones show striking differences in their response to oxidative stress. First, the basal expression of SOD is very different. Symbiotic animal cells have a higher isoform diversity (number and classes) and a higher activity than the non-symbiotic cells. Second, the symbiotic animal cells of A. viridis also maintain unaltered basal values for cellular damage when exposed to experimental hyperoxia (100% O(2)) or to experimental thermal stress (elevated temperature +7 degrees C above ambient). Under such conditions, A. schmidti modifies its SOD activity significantly. Electrophoretic patterns diversify, global activities diminish and cell damage biomarkers increase. These data suggest symbiotic cells adapt to stress while non-symbiotic cells remain acutely sensitive. In addition to being toxic, high O(2) partial pressure (P(O(2))) may also constitute a preconditioning step for symbiotic animal cells, leading to an adaptation to the hyperoxic condition and, thus, to oxidative stress. Furthermore, in aposymbiotic animal cells of A. viridis, repression of some animal SOD isoforms is observed. Meanwhile, in cultured symbionts, new activity bands are induced, suggesting that the host might protect its zooxanthellae in hospite. Similar results have been observed in other symbiotic organisms, such as the sea anemone Aiptasia pulchella and the scleractinian coral Stylophora pistillata. Molecular or physical interactions between the two symbiotic partners may explain such variations in SOD activity and might confer oxidative stress tolerance to the animal host.

  16. Modelling the regulation of thermal adaptation in Candida albicans, a major fungal pathogen of humans.

    Directory of Open Access Journals (Sweden)

    Michelle D Leach

    Full Text Available Eukaryotic cells have evolved mechanisms to sense and adapt to dynamic environmental changes. Adaptation to thermal insults, in particular, is essential for their survival. The major fungal pathogen of humans, Candida albicans, is obligately associated with warm-blooded animals and hence occupies thermally buffered niches. Yet during its evolution in the host it has retained a bona fide heat shock response whilst other stress responses have diverged significantly. Furthermore the heat shock response is essential for the virulence of C. albicans. With a view to understanding the relevance of this response to infection we have explored the dynamic regulation of thermal adaptation using an integrative systems biology approach. Our mathematical model of thermal regulation, which has been validated experimentally in C. albicans, describes the dynamic autoregulation of the heat shock transcription factor Hsf1 and the essential chaperone protein Hsp90. We have used this model to show that the thermal adaptation system displays perfect adaptation, that it retains a transient molecular memory, and that Hsf1 is activated during thermal transitions that mimic fever. In addition to providing explanations for the evolutionary conservation of the heat shock response in this pathogen and the relevant of this response to infection, our model provides a platform for the analysis of thermal adaptation in other eukaryotic cells.

  17. Temperature-induced physiological stress and reproductive characteristics of the migratory seahorse Hippocampus erectus during a thermal stress simulation.

    Science.gov (United States)

    Qin, Geng; Johnson, Cara; Zhang, Yuan; Zhang, Huixian; Yin, Jianping; Miller, Glen; Turingan, Ralph G; Guisbert, Eric; Lin, Qiang

    2018-05-15

    Inshore-offshore migration occurs frequently in seahorse species either because of prey opportunities or because it is driven by reproduction, and variations in water temperature may dramatically change migratory seahorse behavior and physiology. The present study investigated the behavioral and physiological responses of the lined seahorse Hippocampus erectus under thermal stress and evaluated the potential effects of different temperatures on its reproduction. The results showed that the thermal tolerance of the seahorses was time dependent. Acute thermal stress (30°C, 2-10 hours) increased the basal metabolic rate (breathing rate) and the expression of stress response genes ( Hsp genes) significantly and further stimulated seahorse appetite. Chronic thermal treatment (30°C, 4 weeks) led to a persistently higher basal metabolic rate, higher stress response gene expression, and higher mortality, indicating that the seahorses could not acclimate to chronic thermal stress and might experience massive mortality due to excessive basal metabolic rates and stress damage. Additionally, no significant negative effects on gonad development or reproductive endocrine regulation genes were observed in response to chronic thermal stress, suggesting that seahorse reproductive behavior could adapt to higher-temperature conditions during migration and within seahorse breeding grounds. In conclusion, this simulation experiment indicated that temperature variations during inshore-offshore migration have no effect on reproduction but promote basal metabolic rates and stress responses significantly. Therefore, we suggest that the high observed tolerance of seahorse reproduction was in line with the inshore-offshore reproductive migration pattern of lined seahorse. © 2018. Published by The Company of Biologists Ltd.

  18. Thermal stress and seismogenesis

    International Nuclear Information System (INIS)

    Zhou Huilan; Wei Dongping

    1989-05-01

    In this paper, the Fourier stress method was applied to deal with the problem of plane thermal stress, and a computing formula was given. As an example, we set up a variate temperature field to describe the uplifted upper mantle in Bozhong area of China, and the computing results shows that the maximum value of thermal plane shear stress is up to nearly 7x10 7 P α in two regions of this area. Since the Bohai earthquake (18 July, 1969, M s = 7.4) occurred at the edge of one of them and Tangshan earthquake (28 July, 1976, M s = 7.8) within another, their occurrences can be related reasonably to the thermal stress. (author). 15 refs, 7 figs

  19. Smart thermal patch for adaptive thermotherapy

    KAUST Repository

    Hussain, Muhammad Mustafa

    2015-11-12

    A smart thermal patch for adaptive thermotherapy is provided. In an embodiment, the patch can be a stretchable, non-polymeric, conductive thin film flexible and non-invasive body integrated mobile thermal heater with wireless control capabilities that can be used to provide adaptive thermotherapy. The patch can be geometrically and spatially tunable on various pain locations. Adaptability allows the amount of heating to be tuned based on the temperature of the treated portion.

  20. Soft Thermal Sensor with Mechanical Adaptability.

    Science.gov (United States)

    Yang, Hui; Qi, Dianpeng; Liu, Zhiyuan; Chandran, Bevita K; Wang, Ting; Yu, Jiancan; Chen, Xiaodong

    2016-11-01

    A soft thermal sensor with mechanical adaptability is fabricated by the combination of single-wall carbon nanotubes with carboxyl groups and self-healing polymers. This study demonstrates that this soft sensor has excellent thermal response and mechanical adaptability. It shows tremendous promise for improving the service life of soft artificial-intelligence robots and protecting thermally sensitive electronics from the risk of damage by high temperature. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  1. Understanding the adaptive approach to thermal comfort

    Energy Technology Data Exchange (ETDEWEB)

    Humphreys, M.A. [Oxford Univ. (United Kingdom). Centre for the Study of Christianity and Culture; Nicol, J.F. [Oxford Brookes Univ. (United Kingdom). School of Architecture

    1998-10-01

    This paper explains the adaptive approach to thermal comfort, and an adaptive model for thermal comfort is presented. The model is an example of a complex adaptive system (Casti 1996) whose equilibria are determined by the restrictions acting upon it. People`s adaptive actions are generally effective in securing comfort, which occurs at a wide variety of indoor temperatures. These comfort temperatures depend upon the circumstances in which people live, such as the climate and the heating or cooling regime. The temperatures may be estimated from the mean outdoor temperature and the availability of a heating or cooling plant. The evaluation of the parameters of the adaptive model requires cross-sectional surveys to establish current norms and sequential surveys (with and without intervention) to evaluate the rapidity of people`s adaptive actions. Standards for thermal comfort will need revision in the light of the adaptive approach. Implications of the adaptive model for the HVAC industry are noted.

  2. [Stress-induced cellular adaptive mutagenesis].

    Science.gov (United States)

    Zhu, Linjiang; Li, Qi

    2014-04-01

    The adaptive mutations exist widely in the evolution of cells, such as antibiotic resistance mutations of pathogenic bacteria, adaptive evolution of industrial strains, and cancerization of human somatic cells. However, how these adaptive mutations are generated is still controversial. Based on the mutational analysis models under the nonlethal selection conditions, stress-induced cellular adaptive mutagenesis is proposed as a new evolutionary viewpoint. The hypothetic pathway of stress-induced mutagenesis involves several intracellular physiological responses, including DNA damages caused by accumulation of intracellular toxic chemicals, limitation of DNA MMR (mismatch repair) activity, upregulation of general stress response and activation of SOS response. These responses directly affect the accuracy of DNA replication from a high-fidelity manner to an error-prone one. The state changes of cell physiology significantly increase intracellular mutation rate and recombination activity. In addition, gene transcription under stress condition increases the instability of genome in response to DNA damage, resulting in transcription-associated DNA mutagenesis. In this review, we summarize these two molecular mechanisms of stress-induced mutagenesis and transcription-associated DNA mutagenesis to help better understand the mechanisms of adaptive mutagenesis.

  3. Thermal stress relaxation in magnesium composites during thermal cycling

    Energy Technology Data Exchange (ETDEWEB)

    Trojanova, Z.; Lukac, P. (Karlova Univ., Prague (Czech Republic)); Kiehn, J.; Kainer, K.U.; Mordike, B.L. (Technische Univ. Clausthal, Clausthal-Zellerfeld (Germany))

    1998-01-01

    It has been shown that the internal friction of Mg - Saffil metal matrix composites can be influenced by thermal stresses, if MMCc are submitted to thermal cycling between room temperature and an upper temperature of cycling. These stresses can be accommodated by generation and motion of dislocations giving the formation of the microplastic zones. The thermal stress relaxation depends on the upper temperature of cycling, the volume fraction of reinforcement and the matrix composition and can result in plastic deformation and strain hardening of the matrix without applied stress. The internal friction measurements can be used for non destructive investigation of processes which influence the mechanical properties. (orig.)

  4. Evaluation of properties and thermal stress field for thermal barrier coatings

    Institute of Scientific and Technical Information of China (English)

    王良; 齐红宇; 杨晓光; 李旭

    2008-01-01

    In order to get thermal stress field of the hot section with thermal barrier coating (TBCs), the thermal conductivity and elastic modulus of top-coat are the physical key properties. The porosity of top-coat was tested and evaluated under different high temperatures. The relationship between the microstructure (porosity of top-coat) and properties of TBCs were analyzed to predict the thermal properties of ceramic top-coat, such as thermal conductivity and elastic modulus. The temperature and stress field of the vane with TBCs were simulated using two sets of thermal conductivity data and elastic modulus, which are from literatures and this work, respectively. The results show that the temperature and stress distributions change with thermal conductivity and elastic modulus. The differences of maximum temperatures and stress are 6.5% and 8.0%, respectively.

  5. Transient thermal stresses and stress intensity factors induced by thermal stratification in feedwater lines

    International Nuclear Information System (INIS)

    Sanchez Sarmiento, G.; Pardo, E.

    1985-01-01

    General analytical solutions for the thermal stresses and circumferential crack propagation in piping branches of nuclear power plants, that connect two circuits of the same fluid at different temperatures, are presented in this paper. Under certain conditions, two regions of the fluid possessing both temperatures with a separating layer of small thickness are formed ('flow stratification'). Dimensionless analytical expressions for the steady state temperature distribution in the pipe wall and the corresponding thermal stress are here derived, in terms of the basic geometrical and physical parameters. The position and thickness of the separating layer are considered as data of the model. Stress intensity ranges at any point of the tube wall are then determined. Finally, thermally induced stress intensity factors are calculated for hipothetically inside surface cracks. (orig.)

  6. Hsp90 orchestrates transcriptional regulation by Hsf1 and cell wall remodelling by MAPK signalling during thermal adaptation in a pathogenic yeast.

    Directory of Open Access Journals (Sweden)

    Michelle D Leach

    2012-12-01

    Full Text Available Thermal adaptation is essential in all organisms. In yeasts, the heat shock response is commanded by the heat shock transcription factor Hsf1. Here we have integrated unbiased genetic screens with directed molecular dissection to demonstrate that multiple signalling cascades contribute to thermal adaptation in the pathogenic yeast Candida albicans. We show that the molecular chaperone heat shock protein 90 (Hsp90 interacts with and down-regulates Hsf1 thereby modulating short term thermal adaptation. In the longer term, thermal adaptation depends on key MAP kinase signalling pathways that are associated with cell wall remodelling: the Hog1, Mkc1 and Cek1 pathways. We demonstrate that these pathways are differentially activated and display cross talk during heat shock. As a result ambient temperature significantly affects the resistance of C. albicans cells to cell wall stresses (Calcofluor White and Congo Red, but not osmotic stress (NaCl. We also show that the inactivation of MAP kinase signalling disrupts this cross talk between thermal and cell wall adaptation. Critically, Hsp90 coordinates this cross talk. Genetic and pharmacological inhibition of Hsp90 disrupts the Hsf1-Hsp90 regulatory circuit thereby disturbing HSP gene regulation and reducing the resistance of C. albicans to proteotoxic stresses. Hsp90 depletion also affects cell wall biogenesis by impairing the activation of its client proteins Mkc1 and Hog1, as well as Cek1, which we implicate as a new Hsp90 client in this study. Therefore Hsp90 modulates the short term Hsf1-mediated activation of the classic heat shock response, coordinating this response with long term thermal adaptation via Mkc1- Hog1- and Cek1-mediated cell wall remodelling.

  7. On the Unusual Homeoviscous Adaptation of the Membrane Fatty Acyl Components against the Thermal Stress in RhiΖobium meliloti

    International Nuclear Information System (INIS)

    Kang, Seb Yung; Jung, Seun Ho; Choi, Yong Hoon; Yang, Chul Hak; Kim, Hyun Won

    1999-01-01

    In order to maintain the optimal fluidity in membrane, microorganism genetically regulates the ratio of the unsaturated fatty acids (Ufos) to saturated ones of its biological membrane in response to external perturbing condition such as the change of temperature. The remodelling of fatty acyl chain composition is the most frequently observed response to altered growth temperature. It is reflected in the elevated proportions of unsaturated fatty acid (UFAs) at low temperature. Because cis double bonds, normally positioned at the middle of fatty acyl chains, introduce a kink of approximately 30 .deg. into acyl chain, UFAs pack less compactly and exhibit lower melting points than their saturated homologues. Thus, enrichment of membranes with UFAs offsets, to a significant degree, the increase in membrane order caused by a drop in temperature. This is so called homeoviscous adaptation of the membrane fatty acyl chains against thermal stress. Membrane maintains the optimal viscosity using homeoviscous adaptation.

  8. Thermal Stress Awareness, Self-Study #18649

    Energy Technology Data Exchange (ETDEWEB)

    Chochoms, Michael [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-11-15

    Thermal stresses can expose individuals to a variety of health hazards at work, home, and play. Every year thermal stresses cause severe injuries and death to a large range of people, from elderly people in cities during summer heat waves to young people engaged in winter mountaineering. Awareness is the key to preventing the health hazards associated with thermal stresses. This course is designed for personnel at Los Alamos National Laboratory (LANL). It addresses both heat and cold stresses and discusses their factors, signs and symptoms, treatments, and controls.

  9. A theoretical adaptive model of thermal comfort - Adaptive Predicted Mean Vote (aPMV)

    Energy Technology Data Exchange (ETDEWEB)

    Yao, Runming [School of Construction Management and Engineering, The University of Reading (United Kingdom); Faculty of Urban Construction and Environmental Engineering, Chongqing University (China); Li, Baizhan [Key Laboratory of the Three Gorges Reservoir Region' s Eco-Environment (Ministry of Education), Chongqing University (China); Faculty of Urban Construction and Environmental Engineering, Chongqing University (China); Liu, Jing [School of Construction Management and Engineering, The University of Reading (United Kingdom)

    2009-10-15

    This paper presents in detail a theoretical adaptive model of thermal comfort based on the ''Black Box'' theory, taking into account factors such as culture, climate, social, psychological and behavioural adaptations, which have an impact on the senses used to detect thermal comfort. The model is called the Adaptive Predicted Mean Vote (aPMV) model. The aPMV model explains, by applying the cybernetics concept, the phenomena that the Predicted Mean Vote (PMV) is greater than the Actual Mean Vote (AMV) in free-running buildings, which has been revealed by many researchers in field studies. An Adaptive coefficient ({lambda}) representing the adaptive factors that affect the sense of thermal comfort has been proposed. The empirical coefficients in warm and cool conditions for the Chongqing area in China have been derived by applying the least square method to the monitored onsite environmental data and the thermal comfort survey results. (author)

  10. Quantifying the relevance of adaptive thermal comfort models in moderate thermal climate zones

    Energy Technology Data Exchange (ETDEWEB)

    Hoof, Joost van; Hensen, Jan L.M. [Faculty of Architecture, Building and Planning, Technische Universiteit Eindhoven, Vertigo 6.18, P.O. Box 513, 5600 MB Eindhoven (Netherlands)

    2007-01-15

    Standards governing thermal comfort evaluation are on a constant cycle of revision and public review. One of the main topics being discussed in the latest round was the introduction of an adaptive thermal comfort model, which now forms an optional part of ASHRAE Standard 55. Also on a national level, adaptive thermal comfort guidelines come into being, such as in the Netherlands. This paper discusses two implementations of the adaptive comfort model in terms of usability and energy use for moderate maritime climate zones by means of literature study, a case study comprising temperature measurements, and building performance simulation. It is concluded that for moderate climate zones the adaptive model is only applicable during summer months, and can reduce energy for naturally conditioned buildings. However, the adaptive thermal comfort model has very limited application potential for such climates. Additionally we suggest a temperature parameter with a gradual course to replace the mean monthly outdoor air temperature to avoid step changes in optimum comfort temperatures. (author)

  11. Moderate Thermal Stress Causes Active and Immediate Expulsion of Photosynthetically Damaged Zooxanthellae (Symbiodinium from Corals.

    Directory of Open Access Journals (Sweden)

    Lisa Fujise

    Full Text Available The foundation of coral reef biology is the symbiosis between corals and zooxanthellae (dinoflagellate genus Symbiodinium. Recently, coral bleaching, which often results in mass mortality of corals and the collapse of coral reef ecosystems, has become an important issue around the world as coral reefs decrease in number year after year. To understand the mechanisms underlying coral bleaching, we maintained two species of scleractinian corals (Acroporidae in aquaria under non-thermal stress (27°C and moderate thermal stress conditions (30°C, and we compared the numbers and conditions of the expelled Symbiodinium from these corals. Under non-thermal stress conditions corals actively expel a degraded form of Symbiodinium, which are thought to be digested by their host coral. This response was also observed at 30°C. However, while the expulsion rates of Symbiodinium cells remained constant, the proportion of degraded cells significantly increased at 30°C. This result indicates that corals more actively digest and expel damaged Symbiodinium under thermal stress conditions, likely as a mechanism for coping with environmental change. However, the increase in digested Symbiodinium expulsion under thermal stress may not fully keep up with accumulation of the damaged cells. There are more photosynthetically damaged Symbiodinium upon prolonged exposure to thermal stress, and corals release them without digestion to prevent their accumulation. This response may be an adaptive strategy to moderate stress to ensure survival, but the accumulation of damaged Symbiodinium, which causes subsequent coral deterioration, may occur when the response cannot cope with the magnitude or duration of environmental stress, and this might be a possible mechanism underlying coral bleaching during prolonged moderate thermal stress.

  12. Moderate Thermal Stress Causes Active and Immediate Expulsion of Photosynthetically Damaged Zooxanthellae (Symbiodinium) from Corals.

    Science.gov (United States)

    Fujise, Lisa; Yamashita, Hiroshi; Suzuki, Go; Sasaki, Kengo; Liao, Lawrence M; Koike, Kazuhiko

    2014-01-01

    The foundation of coral reef biology is the symbiosis between corals and zooxanthellae (dinoflagellate genus Symbiodinium). Recently, coral bleaching, which often results in mass mortality of corals and the collapse of coral reef ecosystems, has become an important issue around the world as coral reefs decrease in number year after year. To understand the mechanisms underlying coral bleaching, we maintained two species of scleractinian corals (Acroporidae) in aquaria under non-thermal stress (27°C) and moderate thermal stress conditions (30°C), and we compared the numbers and conditions of the expelled Symbiodinium from these corals. Under non-thermal stress conditions corals actively expel a degraded form of Symbiodinium, which are thought to be digested by their host coral. This response was also observed at 30°C. However, while the expulsion rates of Symbiodinium cells remained constant, the proportion of degraded cells significantly increased at 30°C. This result indicates that corals more actively digest and expel damaged Symbiodinium under thermal stress conditions, likely as a mechanism for coping with environmental change. However, the increase in digested Symbiodinium expulsion under thermal stress may not fully keep up with accumulation of the damaged cells. There are more photosynthetically damaged Symbiodinium upon prolonged exposure to thermal stress, and corals release them without digestion to prevent their accumulation. This response may be an adaptive strategy to moderate stress to ensure survival, but the accumulation of damaged Symbiodinium, which causes subsequent coral deterioration, may occur when the response cannot cope with the magnitude or duration of environmental stress, and this might be a possible mechanism underlying coral bleaching during prolonged moderate thermal stress.

  13. Ghosts of thermal past: reef fish exposed to historic high temperatures have heightened stress response to further stressors

    Science.gov (United States)

    Mills, S. C.; Beldade, R.; Chabanet, P.; Bigot, L.; O'Donnell, J. L.; Bernardi, G.

    2015-12-01

    Individual exposure to stressors can induce changes in physiological stress responses through modulation of the hypothalamic-pituitary-interrenal (HPI) axis. Despite theoretical predictions, little is known about how individuals will respond to unpredictable short-lived stressors, such as thermal events. We examine the primary neuroendocrine response of coral reef fish populations from the Îles Eparses rarely exposed to anthropogenic stress, but that experienced different thermal histories. Skunk anemonefish, Amphiprion akallopisos, showed different cortisol responses to a generic stressor between islands, but not along a latitudinal gradient. Those populations previously exposed to higher maximum temperatures showed greater responses of their HPI axis. Archive data reveal thermal stressor events occur every 1.92-6 yr, suggesting that modifications to the HPI axis could be adaptive. Our results highlight the potential for adaptation of the HPI axis in coral reef fish in response to a climate-induced thermal stressor.

  14. Sequence-Based Analysis of Thermal Adaptation and Protein Energy Landscapes in an Invasive Blue Mussel (Mytilus galloprovincialis).

    Science.gov (United States)

    Saarman, Norah P; Kober, Kord M; Simison, W Brian; Pogson, Grant H

    2017-10-01

    Adaptive responses to thermal stress in poikilotherms plays an important role in determining competitive ability and species distributions. Amino acid substitutions that affect protein stability and modify the thermal optima of orthologous proteins may be particularly important in this context. Here, we examine a set of 2,770 protein-coding genes to determine if proteins in a highly invasive heat tolerant blue mussel (Mytilus galloprovincialis) contain signals of adaptive increases in protein stability relative to orthologs in a more cold tolerant M. trossulus. Such thermal adaptations might help to explain, mechanistically, the success with which the invasive marine mussel M. galloprovincialis has displaced native species in contact zones in the eastern (California) and western (Japan) Pacific. We tested for stabilizing amino acid substitutions in warm tolerant M. galloprovincialis relative to cold tolerant M. trossulus with a generalized linear model that compares in silico estimates of recent changes in protein stability among closely related congeners. Fixed substitutions in M. galloprovincialis were 3,180.0 calories per mol per substitution more stabilizing at genes with both elevated dN/dS ratios and transcriptional responses to heat stress, and 705.8 calories per mol per substitution more stabilizing across all 2,770 loci investigated. Amino acid substitutions concentrated in a small number of genes were more stabilizing in M. galloprovincialis compared with cold tolerant M. trossulus. We also tested for, but did not find, enrichment of a priori GO terms in genes with elevated dN/dS ratios in M. galloprovincialis. This might indicate that selection for thermodynamic stability is generic across all lineages, and suggests that the high change in estimated protein stability that we observed in M. galloprovincialis is driven by selection for extra stabilizing substitutions, rather than by higher incidence of selection in a greater number of genes in this lineage

  15. What is the best clothing to prevent heat and cold stress? Experiences with thermal manikin.

    Science.gov (United States)

    Magyar, Z; Tamas, R

    2013-02-01

    The present study summarizes the current knowledge of the heat and cold stress which might significantly affect military activities and might also occur among travellers who are not well adapted to weather variations during their journey. The selection of the best clothing is a very important factor in preserving thermal comfort. Our experiences with thermal manikin are also represented in this paper.

  16. On the unification of thermal perception and adaptive actions

    Energy Technology Data Exchange (ETDEWEB)

    Haldi, Frederic; Robinson, Darren [Solar Energy and Building Physics Laboratory (LESO-PB), Ecole Polytechnique Federale de Lausanne (EPFL), CH-1015 Lausanne (Switzerland)

    2010-11-15

    Occupants exercise adaptive actions in response to discomforting environmental stimuli in an attempt to restore their comfort. These responses to adaptive actions are either ignored (conventional PMV models) or handled in an aggregated way (adaptive thermal comfort models). Furthermore the availability of adaptive actions and their effectiveness tends to be particular to a given building and climatic context. A good model should predict the probability with which available adaptive actions will be exercised and the feedback to occupants' perceived comfort from these specific actions. In this paper we introduce a new modelling framework which does just that. Informed by results from detailed monitoring campaigns we first present a model to predict the probability distribution of thermal sensation in non air-conditioned buildings and a new method for deducing comfort zones in such buildings. We then introduce a methodology for combining recent advances in the prediction of occupants' adaptive actions with the comfort feedback from these actions. We demonstrate how thermal sensation probability distribution may be deduced accounting for exercised adaptive actions and develop a comprehensive model for predicting comfort temperature which explicitly accounts for probable adaptive actions and their thermal feedback. We go on to describe how this modelling framework, which may be readily applied for thermal comfort prediction in specific building and climatic contexts, significantly deepens our understanding of adaptive thermal comfort mechanisms. Finally, we also describe ways of handling individuals' diversity within this new framework as well as how it may be applied to evaluate visual and olfactory comfort. (author)

  17. DIFFERENTIAL BLOOD COUNT OF TENCH Tinca tinca (Linnaeus, 1758 IN CONDITIONS OF THERMAL STRESS

    Directory of Open Access Journals (Sweden)

    Edhem Hasković

    2014-03-01

    Full Text Available Defining the physiological feature provides an understanding of functional adaptation of species to its ecological niche as well as the various forms of stress factors. This paper gives an overview of changes in certain forms of leukocytes (WBC differential under the influence of thermal stress (increased temperature. In our experiment, we used 46 specimens of tench (Tinca tinca fished in the Jablanica Lake reservoir. Specimens had previously been adapted in specially prepared tanks for 20 days.  The control group of animals (16 was exposed to constant water temperature of 10 0C, while in the treated groups (30, the water temperature was gradually risen to 28 0C and, as such, held for 30 minutes. All specimens were aged 2+ and 3+.It was found that the thermal regime change causes adaptive response of tench specimens by increasing the number of neutrophils and pseudoeosinophils but reduction in the number of lymphocytes. Observed were statistically significant differences in the number of segmented granulocytes, pseudoeosinophils and lymphocytes between the control and the experimental group. However, a significantly higher number of segmented granulocytes and pseudoeosinophils was at the experimental group, while in the control group a number of lymphocytes was significantly higher compared with the experimental group. Neither form of leukocytes showed any significant difference between males and females of the experimental group. It is interesting to note that among individuals from both the control and experimental group, eosinophils and monocytes were rarely noticed, while basophils were not found at all. Key words: thermal stress, tench, Tinca tinca, pseudoeosinophils

  18. Physiological Responses to Thermal Stress and Exercise

    Science.gov (United States)

    Iyota, Hiroyuki; Ohya, Akira; Yamagata, Junko; Suzuki, Takashi; Miyagawa, Toshiaki; Kawabata, Takashi

    The simple and noninvasive measuring methods of bioinstrumentation in humans is required for optimization of air conditioning and management of thermal environments, taking into consideration the individual specificity of the human body as well as the stress conditions affecting each. Changes in human blood circulation were induced with environmental factors such as heat, cold, exercise, mental stress, and so on. In this study, the physiological responses of human body to heat stress and exercise were investigated in the initial phase of the developmental research. We measured the body core and skin temperatures, skin blood flow, and pulse wave as the indices of the adaptation of the cardiovascular system. A laser Doppler skin blood flowmetry using an optical-sensor with a small portable data logger was employed for the measurement. These results reveal the heat-stress and exercise-induced circulatory responses, which are under the control of the sympathetic nerve system. Furthermore, it was suggested that the activity of the sympathetic nervous system could be evaluated from the signals of the pulse wave included in the signals derived from skin blood flow by means of heart rate variability assessments and detecting peak heights of velocity-plethysmogram.

  19. Residual stress evolution regularity in thermal barrier coatings under thermal shock loading

    Directory of Open Access Journals (Sweden)

    Ximin Chen

    2014-01-01

    Full Text Available Residual stress evolution regularity in thermal barrier ceramic coatings (TBCs under different cycles of thermal shock loading of 1100°C was investigated by the microscopic digital image correlation (DIC and micro-Raman spectroscopy, respectively. The obtained results showed that, as the cycle number of the thermal shock loading increases, the evolution of the residual stress undergoes three distinct stages: a sharp increase, a gradual change, and a reduction. The extension stress near the TBC surface is fast transformed to compressive one through just one thermal cycle. After different thermal shock cycles with peak temperature of 1100°C, phase transformation in TBC does not happen, whereas the generation, development, evolution of the thermally grown oxide (TGO layer and micro-cracks are the main reasons causing the evolution regularity of the residual stress.

  20. Electric foot shock stress adaptation: Does it exist or not?

    Science.gov (United States)

    Bali, Anjana; Jaggi, Amteshwar Singh

    2015-06-01

    Stress adaptation is a protective phenomenon against repeated stress exposure and is characterized by a decreased responsiveness to a repeated stress stimulus. The adaptation is associated with a complex cascade of events, including the changes in behavior, neurotransmitter and gene expression levels. The non-adaptation or maladaptation to stress may underlie the affective disorders, such as anxiety, depression and post-traumatic stress disorder (PTSD). Electric foot shock is a complex stressor, which includes both physical and emotional components. Unlike immobilization, restraint and cold immersion stress, the phenomenon of stress adaptation is not very well defined in response to electric foot shock. A number of preclinical studies have reported the development of adaptation to electric foot shock stress. However, evidence also reveals the non-adaptive behavior in response to foot shocks. The distinct adaptive/non-adaptive responses may be possibly influenced by the type, intensity, and duration of the stress. The present review discusses the existence or non-existence of adaptation to electric foot shock stress along with possible mechanism. Copyright © 2015 Elsevier Inc. All rights reserved.

  1. Haemoglobin-mediated response to hyper-thermal stress in the keystone species Daphnia magna.

    Science.gov (United States)

    Cuenca Cambronero, Maria; Zeis, Bettina; Orsini, Luisa

    2018-01-01

    Anthropogenic global warming has become a major geological and environmental force driving drastic changes in natural ecosystems. Due to the high thermal conductivity of water and the effects of temperature on metabolic processes, freshwater ecosystems are among the most impacted by these changes. The ability to tolerate changes in temperature may determine species long-term survival and fitness. Therefore, it is critical to identify coping mechanisms to thermal and hyper-thermal stress in aquatic organisms. A central regulatory element compensating for changes in oxygen supply and ambient temperature is the respiratory protein haemoglobin (Hb). Here, we quantify Hb plastic and evolutionary response in Daphnia magna subpopulations resurrected from the sedimentary archive of a lake with known history of increase in average temperature and recurrence of heat waves. By measuring constitutive changes in crude Hb protein content among subpopulations, we assessed evolution of the Hb gene family in response to temperature increase. To quantify the contribution of plasticity in the response of this gene family to hyper-thermal stress, we quantified changes in Hb content in all subpopulations under hyper-thermal stress as compared to nonstressful temperature. Further, we tested competitive abilities of genotypes as a function of their Hb content, constitutive and induced. We found that Hb-rich genotypes have superior competitive abilities as compared to Hb-poor genotypes under hyper-thermal stress after a period of acclimation. These findings suggest that whereas long-term adjustment to higher occurrence of heat waves may require a combination of plasticity and genetic adaptation, plasticity is most likely the coping mechanism to hyper-thermal stress in the short term. Our study suggests that with higher occurrence of heat waves, Hb-rich genotypes may be favoured with potential long-term impact on population genetic diversity.

  2. Non-uniform temperature gradients and thermal stresses produced ...

    Indian Academy of Sciences (India)

    thermally-induced stress distributions in a hollow steel sphere heated by a moving uniform ... models to evaluate temperatures according to the frictional heat generation, ... of these thermal effects include thermal stress, strain and deformation.

  3. 40 CFR 90.329 - Catalyst thermal stress test.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Catalyst thermal stress test. 90.329... Equipment Provisions § 90.329 Catalyst thermal stress test. (a) Oven characteristics. The oven used for thermally stressing the test catalyst must be capable of maintaining a temperature of 500 ±5 °C and 1000 ±10...

  4. Effect of multiple stress factors (thermal, nutritional and pregnancy type) on adaptive capability of native ewes under semi-arid environment.

    Science.gov (United States)

    Dias E Silva, Tairon Pannunzio; Costa Torreão, Jacira Neves da; Torreão Marques, Carlo Aldrovandi; de Araújo, Marcos Jácome; Bezerra, Leílson Rocha; Kumar Dhanasekaran, Dinesh; Sejian, Veerasamy

    2016-07-01

    This study was conducted to evaluate the effect of multiple stress factors (thermal, nutritional and pregnancy type) on two different native track breeds of ewes as reflected by their adaptive capability under semi-arid environment. The multiple stressor experiment was conducted in twenty-four ewes (12 Santa Inês and 12 Morada Nova ewes). Both heat stress and pregnancy stress was common to all four groups. However, the animals were divided into further two groups within each breed on the basis of nutrition regimen. According the groupings were: Group 1 (Six Santa Ines ewes; heat stress; nutrition at 0.5% of BW; single pregnancy); Group 2 (Six Santa Ines ewes; heat stress; nutrition at 1.5% BW; twin pregnancy); groups Group 3 (Six Morada Nova ewes; heat stress; nutrition at 0.5% of BW; single pregnancy); Group 4 (Six Morada Nova ewes; heat stress; nutrition at 1.5% BW; twin pregnancy). All the animals in the experiment were pregnant. Heat stress was induced by exposing all animals to summer heat stress in outside environment while the nutritional regimen followed was at 0.5% and 1.5% level of body weight (BW) respectively in each breed. The experiment was conducted in a completely randomized design with two breeds, two nutritional treatments and two pregnancy types, 10 repetitions for physiological parameters and six for blood parameters, with repeated measures over time. Physiological parameters (respiratory rate, pulse rate and rectal temperature) were measured with the animals at rest in the morning and afternoon, 0600-0700 and 1300-1400h, respectively, every seven days. Blood samples were collected every 14d for determination of serum glucose, triglycerides, cholesterol, urea and creatinine. We found interaction effect between breed and pregnancy type on respiratory rate and rectal temperature with greater values in Santa Inês ewes than Morada Nova ewes. However, there was no significant fixed effect of pregnancy type and supplementation level on physiological

  5. Thermal stresses in long prisms by relaxation methods

    International Nuclear Information System (INIS)

    Cummins, J.D.

    1959-07-01

    A general method is presented for calculating the elastic thermal stresses in long prisms which are producing heat and are not solvable by simple analytical methods. The problem of an inverted lattice i.e. an hexagonal coolant passage surrounded by hexagonal fuel elements is considered and the temperature and principal thermal stress distributions evaluated for the particular case of 20% coolant. The maximum thermal stress for this type of fuel element is about the same as the maximum thermal stress in a cylindrical fuel element surrounded by a sea of coolant assuming the existence of the same maximum temperature drop and material properties. (author)

  6. Thermal stresses in long prisms by relaxation methods

    Energy Technology Data Exchange (ETDEWEB)

    Cummins, J D [Atomic Energy Establishment, Winfrith, Dorchester, Dorset (United Kingdom)

    1959-07-15

    A general method is presented for calculating the elastic thermal stresses in long prisms which are producing heat and are not solvable by simple analytical methods. The problem of an inverted lattice i.e. an hexagonal coolant passage surrounded by hexagonal fuel elements is considered and the temperature and principal thermal stress distributions evaluated for the particular case of 20% coolant. The maximum thermal stress for this type of fuel element is about the same as the maximum thermal stress in a cylindrical fuel element surrounded by a sea of coolant assuming the existence of the same maximum temperature drop and material properties. (author)

  7. Ecology of anuran populations inhabiting thermally stressed aquatic ecosystems, with emphasis on larval Rana pipiens and Bufo terrestris

    International Nuclear Information System (INIS)

    Nelson, D.H.

    1974-01-01

    Field and laboratory studies were conducted to determine the responses of anuran populations to thermally stressed aquatic ecosystems. Adult and larval amphibians were sampled in and around a cool arm of a 67 ha reservoir that receives high temperature effluent from a nuclear production reactor on the Savannah River Plant (SRP) in South Carolina. Patterns for some species were compared with data from nearby unheated areas and analyzed in terms of the thermal gradient (16-45 C) extending the length of the reservoir's cool arm. The adaptation to breeding during nocturnal rainfall fortuitously confers a double advantage especially to anurans breeding in thermally stressed waters. (U.S.)

  8. Thermal stress analysis of a planar SOFC stack

    Science.gov (United States)

    Lin, Chih-Kuang; Chen, Tsung-Ting; Chyou, Yau-Pin; Chiang, Lieh-Kwang

    The aim of this study is, by using finite element analysis (FEA), to characterize the thermal stress distribution in a planar solid oxide fuel cell (SOFC) stack during various stages. The temperature profiles generated by an integrated thermo-electrochemical model were applied to calculate the thermal stress distributions in a multiple-cell SOFC stack by using a three-dimensional (3D) FEA model. The constructed 3D FEA model consists of the complete components used in a practical SOFC stack, including positive electrode-electrolyte-negative electrode (PEN) assembly, interconnect, nickel mesh, and gas-tight glass-ceramic seals. Incorporation of the glass-ceramic sealant, which was never considered in previous studies, into the 3D FEA model would produce more realistic results in thermal stress analysis and enhance the reliability of predicting potential failure locations in an SOFC stack. The effects of stack support condition, viscous behavior of the glass-ceramic sealant, temperature gradient, and thermal expansion mismatch between components were characterized. Modeling results indicated that a change in the support condition at the bottom frame of the SOFC stack would not cause significant changes in thermal stress distribution. Thermal stress distribution did not differ significantly in each unit cell of the multiple-cell stack due to a comparable in-plane temperature profile. By considering the viscous characteristics of the glass-ceramic sealant at temperatures above the glass-transition temperature, relaxation of thermal stresses in the PEN was predicted. The thermal expansion behavior of the metallic interconnect/frame had a greater influence on the thermal stress distribution in the PEN than did that of the glass-ceramic sealant due to the domination of interconnect/frame in the volume of a planar SOFC assembly.

  9. 40 CFR 91.427 - Catalyst thermal stress resistance evaluation.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Catalyst thermal stress resistance... Procedures § 91.427 Catalyst thermal stress resistance evaluation. (a)(1) The purpose of the evaluation procedure specified in this section is to determine the effect of thermal stress on catalyst conversion...

  10. 40 CFR 90.427 - Catalyst thermal stress resistance evaluation.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Catalyst thermal stress resistance... Gaseous Exhaust Test Procedures § 90.427 Catalyst thermal stress resistance evaluation. (a) The purpose of... catalyst conversion efficiency for Phase 1 engines. The thermal stress is imposed on the test catalyst by...

  11. Thermal stress-dependent dilation of concrete

    International Nuclear Information System (INIS)

    Pfeiffer, P.A.; Marchertas, A.H.

    1984-01-01

    Recent studies in nuclear fast reactor safety consider the possibility of concrete containment being subjected to extremely severe environmental conditions. Certain safety scenarios subject the concrete to very high temperatures hence raising the concern of containment integrity. Some of the main detrimental effects of high temperature on concrete are: reduction of strength, redistribution of moisture and etc. Consequently, analytical prediction of concrete response under the high temperature conditions becomes very complex. A rather simple but important experiment of concrete at high temperatures was conducted by Anderberg and Thelandersson. The test samples were small so that moisture was free to evaporate with no appreciable gradient as the temperature increased. Their results revealed that good correlation with analysis could be obtained if thermal expansion was made a function of both temperature and stress. The method of relating the thermal strain to temperature and stress has been integrated into the TEMP-STRESS code. Thus, high temperature concrete computational capability is now available for thermal-stress calculations

  12. Theory of thermal stresses

    CERN Document Server

    Boley, Bruno A

    1997-01-01

    Highly regarded text presents detailed discussion of fundamental aspects of theory, background, problems with detailed solutions. Basics of thermoelasticity, heat transfer theory, thermal stress analysis, more. 1985 edition.

  13. Stress, Adaptive Coping, and Life Satisfaction

    Science.gov (United States)

    Buser, Juleen K.; Kearney, Anne

    2017-01-01

    The authors examined the relationship between stress, adaptive coping, and life satisfaction among college students who reported having a friend or family member with eating disorder symptomatology. A hierarchical regression confirmed the study's hypotheses. Higher stress was linked with less life satisfaction. After stress was controlled, plan…

  14. Thermally developing forced convection and the corresponding thermal stresses in a porous plate channel

    Institute of Scientific and Technical Information of China (English)

    YANG Xiao; LIU Xuemei

    2007-01-01

    Based on the Darcy fluid model, by considering the effects of viscous dissipation due to the interaction between solid skeleton and pore fluid flow and thermal conduction in the direction of the fluid flow, the thermally developing forced convection of the local thermal equili- brium and the corresponding thermal stresses in a semi- infmite saturated porous plate channel are investigated in this paper. The expressions of temperature, local Nusselt number and corresponding thermal stresses are obtained by means of the Fourier series, and the distributions of the same are also shown. Furthermore, influences of the Péclet number (Pe) and Brinkman number (Br) on temperature, Nusselt number (Nu) and thermal stress are revealed numerically.

  15. Feedback effect of human physical and psychological adaption on time period of thermal adaption in naturally ventilated building

    DEFF Research Database (Denmark)

    liu, weiwei; Huangfu, Hao; Xiong, Jing

    2014-01-01

    This study proposed a method to determine time period of thermal adaption for occupants in naturally ventilated building, and analyzed the synergistic and separate feedback effect of the physical and psychological adaption modes on the time period of thermal adaption. Using the method, the values...... of the time period of thermal adaption were obtained on the basis of the data from a long-term field survey conducted in two typical naturally ventilated offices located in Changsha, China. The results showed that the occupants need to take 4.25 days to fully adapt to a step-change in outdoor air temperature...

  16. Coatings influencing thermal stress in photonic crystal fiber laser

    Science.gov (United States)

    Pang, Dongqing; Li, Yan; Li, Yao; Hu, Minglie

    2018-06-01

    We studied how coating materials influence the thermal stress in the fiber core for three holding methods by simulating the temperature distribution and the thermal stress distribution in the photonic-crystal fiber laser. The results show that coating materials strongly influence both the thermal stress in the fiber core and the stress differences caused by holding methods. On the basis of the results, a two-coating PCF was designed. This design reduces the stress differences caused by variant holding conditions to zero, then the stability of laser operations can be improved.

  17. Evaluation charts of thermal stresses in cylindrical vessels induced by thermal stratification of contained fluid

    International Nuclear Information System (INIS)

    Furuhashi, Ichiro; Kawasaki, Nobuchika; Kasahara, Naoto

    2008-01-01

    Temperature and thermal stress in cylindrical vessels were analysed for the thermal stratification of contained fluid. Two kinds of temperature analysis results were obtained such as the exact temperature solution of eigenfunction series and the simple approximate one by the temperature profile method. Furthermore, thermal stress shell solutions were obtained for the simple approximate temperatures. Through comparison with FEM analyses, these solutions were proved to be adequate. The simple temperature solution is described by one parameter that is the temperature decay coefficient. The thermal stress shell solutions are described by two parameters. One is the ratio between the temperature decay coefficient and the load decay coefficient. Another is the nondimensional width of stratification. These solutions are so described by few parameters that those are suitable for the simplified thermal stress evaluation charts. These charts enable quick and accurate thermal stress evaluations of cylindrical vessel of this problem compared with conventional methods. (author)

  18. Evaluation charts of thermal stresses in cylindrical vessels induced by thermal stratification of contained fluid

    International Nuclear Information System (INIS)

    Furuhashi, Ichiro; Kawasaki, Nobuchika; Kasahara, Naoto

    2007-01-01

    Temperature and thermal stress in cylindrical vessels were analysed for the thermal stratification of contained fluid. Two kinds of temperature analysis results were obtained such as the exact temperature solution of eigen-function series and the simple approximate one by the temperature profile method. Furthermore, shell solutions of thermal stress were obtained for the simple approximate temperatures. Through comparison with FEM analyses, these solutions were proved to be adequate. The simple temperature solution is described by one parameter that is the temperature decay factor. The shell solutions of thermal stress are described by two parameters. One is the ratio between the temperature decay factor and the local decay factor. Another is the non-dimensional width of stratification. These solution are so described by few parameters that those are suitable for the simplified thermal stress evaluation charts. These charts enable quick and accurate thermal stress evaluations of cylindrical vessel of this problem compared with conventional methods. (author)

  19. Adaptive thermal comfort for buildings in Portugal based on occupants' thermal perception

    Energy Technology Data Exchange (ETDEWEB)

    Matias, L.; Pina Santos, C.; Rebelo, M. [LNEC National Laboratory for Civil Engineering, Lisbon (Portugal); Almeida, S. [FCT Foundation for Science and Technology, Lisbon (Portugal); Correia Guedes, M. [IST Higher Technical Inst., Lisbon (Portugal)

    2009-07-01

    The use of air conditioning systems in Portugal has increased in recent years. Most new service buildings are equipped with mechanical air conditioning systems, either due to commercial reasons, productivity, or due to high internal thermal loads, and solar gains through windows. However, a large percentage of older service buildings are still naturally ventilated. In ASHRAE 55 thermal comfort standard, an adaptive model was adopted as an optional method for determining acceptable thermal conditions in naturally conditioned spaces. Recently, Portugal's National Laboratory for Civil Engineering (LNEC) initiated an interdisciplinary research study in this field. The research team of physicists, social scientists, and civil engineers developed better modeling of adaptive thermal strategies. This paper described the adaptive approach that defined indoor thermal comfort requirements applicable to Portuguese buildings. The study focused on assessing, in real use conditions, indoor environments and the response of occupants of office and educational buildings, and homes for the elderly. The results were obtained from 285 field surveys carried out on 40 buildings and a set of 2367 questionnaires completed by occupants. Field surveys assessed and measured the main indoor environmental parameters during summer, winter and mid-season. This paper included the results of the analysis to the occupants' thermal perception and expectation, by relating them to both measured and collected indoor thermal environments and outdoor climate. The relation between the occupants' thermal sensation and preference was analysed for different types of activities, throughout different seasons. Results showed that occupants may tolerate broader temperature ranges than those indicated in current standards, particularly in the heating season. 10 refs., 3 tabs., 9 figs.

  20. Thermal stress effects in intermetallic matrix composites

    Science.gov (United States)

    Wright, P. K.; Sensmeier, M. D.; Kupperman, D. S.; Wadley, H. N. G.

    1993-01-01

    Intermetallic matrix composites develop residual stresses from the large thermal expansion mismatch (delta-alpha) between the fibers and matrix. This work was undertaken to: establish improved techniques to measure these thermal stresses in IMC's; determine residual stresses in a variety of IMC systems by experiments and modeling; and, determine the effect of residual stresses on selected mechanical properties of an IMC. X ray diffraction (XRD), neutron diffraction (ND), synchrotron XRD (SXRD), and ultrasonics (US) techniques for measuring thermal stresses in IMC were examined and ND was selected as the most promising technique. ND was demonstrated on a variety of IMC systems encompassing Ti- and Ni-base matrices, SiC, W, and Al2O3 fibers, and different fiber fractions (Vf). Experimental results on these systems agreed with predictions of a concentric cylinder model. In SiC/Ti-base systems, little yielding was found and stresses were controlled primarily by delta-alpha and Vf. In Ni-base matrix systems, yield strength of the matrix and Vf controlled stress levels. The longitudinal residual stresses in SCS-6/Ti-24Al-llNb composite were modified by thermomechanical processing. Increasing residual stress decreased ultimate tensile strength in agreement with model predictions. Fiber pushout strength showed an unexpected inverse correlation with residual stress. In-plane shear yield strength showed no dependence on residual stress. Higher levels of residual tension led to higher fatigue crack growth rates, as suggested by matrix mean stress effects.

  1. 40 CFR 91.329 - Catalyst thermal stress test.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Catalyst thermal stress test. 91.329....329 Catalyst thermal stress test. (a) Oven characteristics. The oven used for termally stressing the test catalyst must be capable of maintaining a temperature of 500 ±5 °C and 1000 ±10 °C. (b) Evaluation...

  2. Mitochondrial Stress Signaling Promotes Cellular Adaptations

    Directory of Open Access Journals (Sweden)

    Jayne Alexandra Barbour

    2014-01-01

    Full Text Available Mitochondrial dysfunction has been implicated in the aetiology of many complex diseases, as well as the ageing process. Much of the research on mitochondrial dysfunction has focused on how mitochondrial damage may potentiate pathological phenotypes. The purpose of this review is to draw attention to the less well-studied mechanisms by which the cell adapts to mitochondrial perturbations. This involves communication of stress to the cell and successful induction of quality control responses, which include mitophagy, unfolded protein response, upregulation of antioxidant and DNA repair enzymes, morphological changes, and if all else fails apoptosis. The mitochondrion is an inherently stressful environment and we speculate that dysregulation of stress signaling or an inability to switch on these adaptations during times of mitochondrial stress may underpin mitochondrial dysfunction and hence amount to pathological states over time.

  3. Temperature distribution and thermal stress

    Indian Academy of Sciences (India)

    Abstract. Thermal effects of a double-end-pumped cubic Nd:YVO4 laser crystal are investigated in this paper. A detailed analysis of temperature distribution and thermal stress in cubic crystal with circular shape pumping is discussed. It has been shown that by considering the total input powers as constant, the ...

  4. Thermal stress ratcheting analysis of a time-hardening structure

    International Nuclear Information System (INIS)

    Hada, Kazuhiko

    1999-01-01

    Thermal stress ratcheting and shakedown is analyzed for a time-hardening structure: the yield stress increases as time goes on under exposure to neutron irradiation or thermal aging. New three modes of ratcheting and shakedown are identified as transition to other deformation modes. Stress regimes and thermal ratchet strains are formulated as a function of time-increasing yield stress. Moreover, a new model of trouble occurrence frequency as a modification to a bath-tube curve is proposed for calculating a time period of a thermal cycle. Application of the proposed formulation tells us a benefit of taking into account the time hardening due to neutron irradiation. (author)

  5. Calculation of the thermal stress and thermal resistance of anisotropic materials. II

    Energy Technology Data Exchange (ETDEWEB)

    Krivko, A I; Epishin, A I; Svetlov, I L; Samoilov, A I; Sukhanov, N N

    1989-04-01

    The stressed state in a wedge and in a family of plates cut from single-crystal ingots of 40 axial orientations is analyzed. It is shown that, in contrast to the case of the wedge, the value of the thermal stress tensor components in the plates depends substantially not only on the axial crystallographic orientation but also on the azimuthal orientation. Requirements on the crystallographic orientation of simple single-crystal parts of plate or wedge type are formulated with the aim of decreasing the detrimental effects of thermal stresses. The correctness of the calculations is confirmed by results of thermal fatigue tests of hollow prismatic specimens, i.e., blade simulators with 001, 011, and 111 axial orientations.

  6. Adaptive thermal modeling of Li-ion batteries

    International Nuclear Information System (INIS)

    Shadman Rad, M.; Danilov, D.L.; Baghalha, M.; Kazemeini, M.; Notten, P.H.L.

    2013-01-01

    Highlights: • A simple, accurate and adaptive thermal model is proposed for Li-ion batteries. • Equilibrium voltages, overpotentials and entropy changes are quantified from experimental results. • Entropy changes are highly dependent on the battery State-of-Charge. • Good agreement between simulated and measured heat development is obtained under all conditions. • Radiation contributes to about 50% of heat dissipation at elevated temperatures. -- Abstract: An accurate thermal model to predict the heat generation in rechargeable batteries is an essential tool for advanced thermal management in high power applications, such as electric vehicles. For such applications, the battery materials’ details and cell design are normally not provided. In this work a simple, though accurate, thermal model for batteries has been developed, considering the temperature- and current-dependent overpotential heat generation and State-of-Charge dependent entropy contributions. High power rechargeable Li-ion (7.5 Ah) batteries have been experimentally investigated and the results are used for model verification. It is shown that the State-of-Charge dependent entropy is a significant heat source and is therefore essential to correctly predict the thermal behavior of Li-ion batteries under a wide variety of operating conditions. An adaptive model is introduced to obtain these entropy values. A temperature-dependent equation for heat transfer to the environment is also taken into account. Good agreement between the simulations and measurements is obtained in all cases. The parameters for both the heat generation and heat transfer processes can be applied to the thermal design of advanced battery packs. The proposed methodology is generic and independent on the cell chemistry and battery design. The parameters for the adaptive model can be determined by performing simple cell potential/current and temperature measurements for a limited number of charge/discharge cycles

  7. Numerical thermal mathematical model correlation to thermal balance test using adaptive particle swarm optimization (APSO)

    International Nuclear Information System (INIS)

    Beck, T.; Bieler, A.; Thomas, N.

    2012-01-01

    We present structural and thermal model (STM) tests of the BepiColombo laser altimeter (BELA) receiver baffle with emphasis on the correlation of the data with a thermal mathematical model. The test unit is a part of the thermal and optical protection of the BELA instrument being tested under infrared and solar irradiation at University of Bern. An iterative optimization method known as particle swarm optimization has been adapted to adjust the model parameters, mainly the linear conductivity, in such a way that model and test results match. The thermal model reproduces the thermal tests to an accuracy of 4.2 °C ± 3.2 °C in a temperature range of 200 °C after using only 600 iteration steps of the correlation algorithm. The use of this method brings major benefits to the accuracy of the results as well as to the computational time required for the correlation. - Highlights: ► We present model correlations of the BELA receiver baffle to thermal balance tests. ► Adaptive particle swarm optimization has been adapted for the correlation. ► The method improves the accuracy of the correlation and the computational time.

  8. Transient stress control of aeroengine disks based on active thermal management

    International Nuclear Information System (INIS)

    Ding, Shuiting; Wang, Ziyao; Li, Guo; Liu, Chuankai; Yang, Liu

    2016-01-01

    Highlights: • The essence of cooling in turbine system is a process of thermal management. • Active thermal management is proposed to control transient stress of disks. • The correlation between thermal load and transient stress of disks is built. • Stress level can be declined by actively adjusting the thermal load distribution. • Artificial temperature gradient can be used to counteract stress from rotating. - Abstract: The physical essence of cooling in the turbine system is a process of thermal management. In order to overcome the limits of passive thermal management based on thermal protection, the concept of active thermal management based on thermal load redistribution has been proposed. On this basis, this paper focuses on a near real aeroengine disk during a transient process and studies the stress control mechanism of active thermal management in transient conditions by a semi-analytical method. Active thermal management is conducted by imposing extra heating energy on the disk hub, which is represented by the coefficient of extra heat flow η. The results show that the transient stress level can be effectively controlled by actively adjusting the thermal load distribution. The decline ratio of the peak equivalent stress of the disk hub can be 9.0% for active thermal management load condition (η = 0.2) compared with passive condition (η = 0), even at a rotation speed of 10,000 r/min. The reason may be that the temperature distribution of the disk turns into an artificial V-shape because of the extra heating energy on the hub, and the resulting thermal stresses induced by the negative temperature gradients counteract parts of the stress from rotating.

  9. Exploring the use of thermal infrared imaging in human stress research.

    Directory of Open Access Journals (Sweden)

    Veronika Engert

    Full Text Available High resolution thermal infrared imaging is a pioneering method giving indices of sympathetic activity via the contact-free recording of facial tissues (thermal imprints. Compared to established stress markers, the great advantage of this method is its non-invasiveness. The goal of our study was to pilot the use of thermal infrared imaging in the classical setting of human stress research. Thermal imprints were compared to established stress markers (heart rate, heart rate variability, finger temperature, alpha-amylase and cortisol in 15 participants undergoing anticipation, stress and recovery phases of two laboratory stress tests, the Cold Pressor Test and the Trier Social Stress Test. The majority of the thermal imprints proved to be change-sensitive in both tests. While correlations between the thermal imprints and established stress markers were mostly non-significant, the thermal imprints (but not the established stress makers did correlate with stress-induced mood changes. Multivariate pattern analysis revealed that in contrast to the established stress markers the thermal imprints could not disambiguate anticipation, stress and recovery phases of both tests. Overall, these results suggest that thermal infrared imaging is a valuable method for the estimation of sympathetic activity in the stress laboratory setting. The use of this non-invasive method may be particularly beneficial for covert recordings, in the study of special populations showing difficulties in complying with the standard instruments of data collection and in the domain of psychophysiological covariance research. Meanwhile, the established stress markers seem to be superior when it comes to the characterization of complex physiological states during the different phases of the stress cycle.

  10. SLAC divertor channel entrance thermal stress analysis

    International Nuclear Information System (INIS)

    Johnson, G.L.; Stein, W.; Lu, S.C.; Riddle, R.A.

    1985-01-01

    X-ray beams emerging from the new SLAC electron-positron storage ring (PEP) impinge on the entrance to tangential divertor channels causing highly localized heating in the channel structure. Analyses were completed to determine the temperatures and thermally-induced stresses due to this heating. These parts are cooled with water flowing axially over them at 30 0 C. The current design and operating conditions should result in the entrance to the new divertor channel operating at a peak temperature of 123 0 C with a peak thermal stress at 91% of yield. Any micro-cracks that form due to thermally-induced stresses should not propagate to the coolant wall nor form a path for the coolant to leak into the storage ring vacuum. 34 figs., 4 tabs

  11. Transgenerational stress-adaption: an opportunity for ecological epigenetics.

    Science.gov (United States)

    Weinhold, Arne

    2018-01-01

    In the recent years, there has been considerable interest to investigate the adaptive transgenerational plasticity of plants and how a "stress memory" can be transmitted to the following generation. Although, increasing evidence suggests that transgenerational adaptive responses have widespread ecological relevance, the underlying epigenetic processes have rarely been elucidated. On the other hand, model plant species have been deeply investigated in their genome-wide methylation landscape without connecting this to the ecological reality of the plant. What we need is the combination of an ecological understanding which plant species would benefit from transgenerational epigenetic stress-adaption in their natural habitat, combined with a deeper molecular analysis of non-model organisms. Only such interdisciplinary linkage in an ecological epigenetic study could unravel the full potential that epigenetics could play for the transgenerational stress-adaption of plants.

  12. An analytical study on the thermal stress of mass concrete

    International Nuclear Information System (INIS)

    Yoshida, H.; Sawada, T.; Yamazaki, M.; Miyashita, T.; Morikawa, H.; Hayami, Y.; Shibata, K.

    1983-01-01

    The thermal stress in mass concrete occurs as a result of the effect associated with the heat of hydration of the cement. Sometimes, the excessive stresses cause the cracking or other tensile failure in concrete. Therefore it is becoming necessary in the design and construction of mass concrete to predict the thermal stress. The thermal stress analysis of mass concrete requires to take account of the dependence of the elastic modulus on the age of concrete as well as the stress relaxation by creep effect. The studies of those phenomena and the analytical methods have been reported so far. The paper presents the analytical method and discusses its reliability through the application of the method to the actual structure, measuring the temperatures and the thermal stresses. The method is the time dependent thermal stress analysis based on the finite element method, which takes account of creep effect, the aging of concrete and the effect of temperature variation in time. (orig./HP)

  13. Fatigue crack growth behavior under cyclic thermal transient stress

    International Nuclear Information System (INIS)

    Ueda, Masahiro; Kano, Takashi; Yoshitoshi, Atsushi.

    1986-01-01

    Thermal fatigue tests were performed using straight pipe specimens subjected to cyclic thermal shocks of liquid sodium, and crack growth behaviors were estimated using striation patterns observed clearly on any crack surface. Crack growth rate under cyclic thermal strain reaches the maximum at one depth, and after that it decreases gradually with crack depth. The peak location of crack growth rate becomes deeper by superposition of constant primary stress. Parallel cracks co-existing in the neighborhood move the peak to shallower location and decrease the maximum crack growth rate. The equivalent stress intensity factor range calculated by Walker's formula is successfully applied to the case of negative stress ratio. Fatigue crack growth rate under cyclic thermal strain agreed well with that under the constant temperature equal to the maximum value in the thermal cycle. Simplified methods for calculating the stress intensity factor and the crack interference factor have been developed. Crack growth behavior under thermal fatigue could be well predicted using numerical analysis results. (author)

  14. Fatigue crack growth behavior under cyclic transient thermal stress

    International Nuclear Information System (INIS)

    Ueda, Masahiro; Kano, Takashi; Yoshitoshi, Atsushi.

    1987-01-01

    Thermal fatigue tests were performed using straight pipe specimens subjected to cyclic thermal shocks of liquid sodium, and crack growth behaviors were estimated using striation patterns observed clearly on any crack surface. Crack growth rate under cyclic thermal strain reaches the maximum at one depth, and after that it decreases gradually with crack depth. The peak location of crack growth rate becomes deeper by superposition of constant primary stress. Parallel cracks co-existing in the neighborhood move the peak to shallower location and decrease the maximum crack growth rate. The equivalent stress intensity factor range calculated by Walker's formula is successfully applied to the case of negative stress ratio. Fatigue crack growth rate under cyclic thermal strain agreed well with that under the constant temperature equal to the maximum value in the thermal cycle. Simplified methods for calculating the stress intensity factor and the crack interference factor have been developed. Crack growth behavior under thermal fatigue could be well predicted using numerical analysis results. (author)

  15. Modelling and analysis of radial thermal stresses and temperature ...

    African Journals Online (AJOL)

    A theoretical investigation has been undertaken to study operating temperatures, heat fluxes and radial thermal stresses in the valves of a modern diesel engine with and without air-cavity. Temperatures, heat fluxes and radial thermal stresses were measured theoretically for both cases under all four thermal loading ...

  16. Expression analysis of NOS family and HSP genes during thermal stress in goat ( Capra hircus)

    Science.gov (United States)

    Yadav, Vijay Pratap; Dangi, Satyaveer Singh; Chouhan, Vikrant Singh; Gupta, Mahesh; Dangi, Saroj K.; Singh, Gyanendra; Maurya, Vijay Prakash; Kumar, Puneet; Sarkar, Mihir

    2016-03-01

    Approximately 50 genes other than heat shock protein (HSP) expression changes during thermal stress. These genes like nitric oxide synthase (NOS) need proper attention and investigation to find out their possible role in the adaptation to thermal stress in animals. So, the present study was undertaken to demonstrate the expressions of inducible form type II NOS (iNOS), endothelial type III NOS (eNOS), constitutively expressed enzyme NOS (cNOS), HSP70, and HSP90 in peripheral blood mononuclear cells (PBMCs) during different seasons in Barbari goats. Real-time polymerase chain reaction, western blot, and immunocytochemistry were applied to investigate messenger RNA (mRNA) expression, protein expression, and immunolocalization of examined factors. The mRNA and protein expressions of iNOS, eNOS, cNOS, HSP70, and HSP90 were significantly higher ( P goats.

  17. Temperature and Thermal Stress Analysis of Refractory Products

    Directory of Open Access Journals (Sweden)

    Shaoyang Shi

    2013-05-01

    Full Text Available Firstly current status of temperature and thermal stress research of refractory product at home and aboard are analyzed. Finite element model of two classical refractory products is building by using APDL language. Distribution law of temperature and thermal stress of two typical refractory products-ladles and tundish are analyzed and their structures are optimized. Stress of optimal structure is dropped obviously, and operation life is increased effectively.

  18. Comparative expression profile of NOD1/2 and certain acute inflammatory cytokines in thermal-stressed cell culture model of native and crossbred cattle

    Science.gov (United States)

    Bhanuprakash, V.; Singh, Umesh; Sengar, Gyanendra Singh; Raja, T. V.; Sajjanar, Basavraj; Alex, Rani; Kumar, Sushil; Alyethodi, R. R.; Kumar, Ashish; Sharma, Ankur; Kumar, Suresh; Bhusan, Bharat; Deb, Rajib

    2017-05-01

    Thermotolerance depends mainly on the health and immune status of the animals. The variation in the immune status of the animals may alter the level of tolerance of animals exposed to heat or cold stress. The present study was conducted to investigate the expression profile of two important nucleotide binding and oligomerization domain receptors (NLRs) (NOD1 and NOD2) and their central signalling molecule RIP2 gene during in vitro thermal-stressed bovine peripheral blood mononuclear cells (PBMCs) of native (Sahiwal) and crossbred (Sahiwal X HF) cattle. We also examined the differential expression profile of certain acute inflammatory cytokines in in vitro thermal-stressed PBMC culture among native and its crossbred counterparts. Results revealed that the expression profile of NOD1/2 positively correlates with the thermal stress, signalling molecule and cytokines. Present findings also highlighted that the expression patterns during thermal stress were comparatively superior among indigenous compared to crossbred cattle which may add references regarding the better immune adaptability of Zebu cattle.

  19. Psychosocial stress affects the acquisition of cerebellar-dependent sensorimotor adaptation.

    Science.gov (United States)

    Gheorghe, Delia A; Panouillères, Muriel T N; Walsh, Nicholas D

    2018-03-27

    Despite being overlooked in theoretical models of stress-related disorders, differences in cerebellar structure and function are consistently reported in studies of individuals exposed to current and early-life stressors. However, the mediating processes through which stress impacts upon cerebellar function are currently unknown. The aim of the current experiment was to test the effects of experimentally-induced acute stress on cerebellar functioning, using a classic, forward saccadic adaptation paradigm in healthy, young men and women. Stress induction was achieved by employing the Montreal Imaging Stress Task (MIST), a task employing mental arithmetic and negative social feedback to generate significant physiological and endocrine stress responses. Saccadic adaptation was elicited using the double-step target paradigm. In the experiment, 48 participants matched for gender and age were exposed to either a stress (n = 25) or a control (n = 23) condition. Saliva for cortisol analysis was collected before, immediately after, and 10, and 30 min after the MIST. Saccadic adaptation was assessed approximately 10 min after stress induction, when cortisol levels peaked. Participants in the stress group reported significantly more stress symptoms and exhibited greater total cortisol output compared to controls. The stress manipulation was associated with slower learning rates in the stress group, while control participants acquired adaptation faster. Learning rates were negatively associated with cortisol output and mood disturbance. Results suggest that experimentally-induced stress slowed acquisition of cerebellar-dependent saccadic adaptation, related to increases in cortisol output. These 'proof-of-principle' data demonstrate that stress modulates cerebellar-related functions. Copyright © 2018 Elsevier Ltd. All rights reserved.

  20. An anisotropic thermal-stress model for through-silicon via

    Science.gov (United States)

    Liu, Song; Shan, Guangbao

    2018-02-01

    A two-dimensional thermal-stress model of through-silicon via (TSV) is proposed considering the anisotropic elastic property of the silicon substrate. By using the complex variable approach, the distribution of thermal-stress in the substrate can be characterized more accurately. TCAD 3-D simulations are used to verify the model accuracy and well agree with analytical results (model can be integrated into stress-driven design flow for 3-D IC , leading to the more accurate timing analysis considering the thermal-stress effect. Project supported by the Aerospace Advanced Manufacturing Technology Research Joint Fund (No. U1537208).

  1. Role of high-temperature creep stress in thermally grown oxide growth of thermal barrier coatings

    Energy Technology Data Exchange (ETDEWEB)

    Ogawa, K.; Nakao, Y.; Seo, D.; Miura, H.; Shoji, T. [Tohoku Univ., Sendai (Japan)

    2008-07-01

    Thermally grown oxide (TGO) grows at the top / bond coating interface of the thermal barrier coating (TBC) in service. It is supposed that the failures of the TBC occur due to thermal stress and the decrease of adhesive strength caused by the TGO growth. Recently, large local stress has been found to change both the diffusion constant of oxygen through an existing oxide and the rate of chemical reaction at the oxide / oxidized material interface. Since high thermal stress occurs in the TBC, the volume expansion of the newly grown oxide, and centrifugal force, the growth rate of the TGO may change depending on not only temperature but also the stress. The aim of this study is to make clear the influence of stress on the growth rate of the TGO quantitatively. As a result, the thickness of the TGO clearly increases with increase of the amplitude of the applied stress and temperature. The increase rate of the TGO thickness is approximately 23% when the applied stress is increased from 0 to 205 MPa at 900 C, and approximately 29% when the stress is increased from 0 to 150 MPa at 950 C. (orig.)

  2. Finite element analysis of thermal stress distribution in different ...

    African Journals Online (AJOL)

    Nigerian Journal of Clinical Practice. Journal Home ... Von Mises and thermal stress distributions were evaluated. Results: In all ... distribution. Key words: Amalgam, finite element method, glass ionomer cement, resin composite, thermal stress ...

  3. Thermal stress analysis of space shuttle orbiter wing skin panel and thermal protection system

    Science.gov (United States)

    Ko, William L.; Jenkins, Jerald M.

    1987-01-01

    Preflight thermal stress analysis of the space shuttle orbiter wing skin panel and the thermal protection system (TPS) was performed. The heated skin panel analyzed was rectangular in shape and contained a small square cool region at its center. The wing skin immediately outside the cool region was found to be close to the state of elastic instability in the chordwise direction based on the conservative temperature distribution. The wing skin was found to be quite stable in the spanwise direction. The potential wing skin thermal instability was not severe enough to tear apart the strain isolation pad (SIP) layer. Also, the preflight thermal stress analysis was performed on the TPS tile under the most severe temperature gradient during the simulated reentry heating. The tensile thermal stress induced in the TPS tile was found to be much lower than the tensile strength of the TPS material. The thermal bending of the TPS tile was not severe enough to cause tearing of the SIP layer.

  4. Quantifying the relevance of adaptive thermal comfort models in moderate thermal climate zones

    NARCIS (Netherlands)

    Hoof, van J.; Hensen, J.L.M.

    2007-01-01

    Standards governing thermal comfort evaluation are on a constant cycle of revision and public review. One of the main topics being discussed in the latest round was the introduction of an adaptive thermal comfort model, which now forms an optional part of ASHRAE Standard 55. Also on a national

  5. ADAPTATION MODEL FOR REDUCING THE MANAGERIAL STRESS

    Directory of Open Access Journals (Sweden)

    VIOLETA GLIGOROVSKI

    2017-12-01

    Full Text Available Changes are an inseparable component of the company's life cycle and they can contribute to its essential growth in the future. The purpose of this paper is to explain managerial stress caused by implementation of changes and creating an adaptation model to decrease managerial stress. How much the manager will successfully lead the project for implementation of a change and how much they will manage to amortize stress among employees, mostly depends on their expertise, knowledge and skills to accurately and comprehensively inform and integrate the employees in the overall process. The adaptation model is actually a new approach and recommendation for managers for dealing with stress when the changes are implemented. Methodology. For this purpose, the data presented, in fact, were collected through a questionnaire that was submitted to 61 respondents/ managers. The data were measured using the Likert scale from 1 to 7. Namely, with the help of the Likert scale, quantification of stress was made in relation to the various variables that were identified as the most important for the researched issues. An adaption model (new approach for amortizing changes was created using the DIA Diagram application, to show the relations between manager and the relevant amortization approaches.

  6. Calculation of thermal stresses in graphite fuel blocks

    International Nuclear Information System (INIS)

    Lejeail, Y.; Cabrillat, M.T.

    2005-01-01

    This paper presents a parametric study of temperature and thermal stress calculations inside a HTGR core graphite block, taking into account the effect of fluence on the thermal and mechanical properties, up to 4. 10 21 n/cm 2 . The Finite Element model, realized with Cast3M CEA code, includes the effects of irradiation creep, which tends to produce secondary stress relaxation. Then, the Weibull weakest link theory is recalled, evaluating the possible effects of volume, stress field distribution (loading factor), and multiaxiality for graphite-type materials, and giving the methodology to compare the stress to rupture for the structure to the one obtained from characterization, in the general case. The maximum of the Weibull stress in Finite Element calculations is compared to the value for tensile specimens. It is found that the maximum of the stress corresponds to the end of the irradiation cycle, after reactor shutdown, since both thermal conductivity and Young's modulus increase with time. However, this behaviour is partly counterbalanced by the increase of material strength with irradiation. (authors)

  7. The relationship between bioclimatic thermal stress and subjective thermal sensation in pedestrian spaces

    Science.gov (United States)

    Pearlmutter, David; Jiao, Dixin; Garb, Yaakov

    2014-12-01

    Outdoor thermal comfort has important implications for urban planning and energy consumption in the built environment. To better understand the relation of subjective thermal experience to bioclimatic thermal stress in such contexts, this study compares micrometeorological and perceptual data from urban spaces in the hot-arid Negev region of Israel. Pedestrians reported on their thermal sensation in these spaces, whereas radiation and convection-related data were used to compute the Index of Thermal Stress (ITS) and physiologically equivalent temperature (PET). The former is a straightforward characterization of energy exchanges between the human body and its surroundings, without any conversion to an "equivalent temperature." Although the relation of ITS to subjective thermal sensation has been analyzed in the past under controlled indoor conditions, this paper offers the first analysis of this relation in an outdoor setting. ITS alone can account for nearly 60 % of the variance in pedestrians' thermal sensation under outdoor conditions, somewhat more than PET. A series of regressions with individual contextual variables and ITS identified those factors which accounted for additional variance in thermal sensation, whereas multivariate analyses indicated the considerable predictive power ( R-square = 0.74) of models including multiple contextual variables in addition to ITS. Our findings indicate that pedestrians experiencing variable outdoor conditions have a greater tolerance for incremental changes in thermal stress than has been shown previously under controlled indoor conditions, with a tapering of responses at high values of ITS. However, the thresholds of ITS corresponding to thermal "neutrality" and thermal "acceptability" are quite consistent regardless of context.

  8. Coherent gradient sensing method for measuring thermal stress field of thermal barrier coating structures

    Directory of Open Access Journals (Sweden)

    Kang Ma

    2017-01-01

    Full Text Available Coherent gradient sensing (CGS method can be used to measure the slope of a reflective surface, and has the merits of full-field, non-contact, and real-time measurement. In this study, the thermal stress field of thermal barrier coating (TBC structures is measured by CGS method. Two kinds of powders were sprayed onto Ni-based alloy using a plasma spraying method to obtain two groups of film–substrate specimens. The specimens were then heated with an oxy-acetylene flame. The resulting thermal mismatch between the film and substrate led to out-of-plane deformation of the specimen. The deformation was measured by the reflective CGS method and the thermal stress field of the structure was obtained through calibration with the help of finite element analysis. Both the experiment and numerical results showed that the thermal stress field of TBC structures can be successfully measured by CGS method.

  9. Integrated physiological mechanisms of exercise performance, adaptation, and maladaptation to heat stress.

    Science.gov (United States)

    Sawka, Michael N; Leon, Lisa R; Montain, Scott J; Sonna, Larry A

    2011-10-01

    This article emphasizes significant recent advances regarding heat stress and its impact on exercise performance, adaptations, fluid electrolyte imbalances, and pathophysiology. During exercise-heat stress, the physiological burden of supporting high skin blood flow and high sweating rates can impose considerable cardiovascular strain and initiate a cascade of pathophysiological events leading to heat stroke. We examine the association between heat stress, particularly high skin temperature, on diminishing cardiovascular/aerobic reserves as well as increasing relative intensity and perceptual cues that degrade aerobic exercise performance. We discuss novel systemic (heat acclimation) and cellular (acquired thermal tolerance) adaptations that improve performance in hot and temperate environments and protect organs from heat stroke as well as other dissimilar stresses. We delineate how heat stroke evolves from gut underperfusion/ischemia causing endotoxin release or the release of mitochondrial DNA fragments in response to cell necrosis, to mediate a systemic inflammatory syndrome inducing coagulopathies, immune dysfunction, cytokine modulation, and multiorgan damage and failure. We discuss how an inflammatory response that induces simultaneous fever and/or prior exposure to a pathogen (e.g., viral infection) that deactivates molecular protective mechanisms interacts synergistically with the hyperthermia of exercise to perhaps explain heat stroke cases reported in low-risk populations performing routine activities. Importantly, we question the "traditional" notion that high core temperature is the critical mediator of exercise performance degradation and heat stroke. Published 2011. This article is a U.S. Government work and is in the public domain in the USA.

  10. Vascular thermal adaptation in tumors and normal tissue in rats

    International Nuclear Information System (INIS)

    Nah, Byung Sik; Choi, Ihl-Bohng; Oh, Won Young; Osborn, James L.; Song, Chang W.

    1996-01-01

    Purpose: The vascular thermal adaptation in the R3230 adenocarcinoma, skin and muscle in the legs of Fischer rats was studied. Methods and Materials: The legs of Fischer rats bearing the R3230 AC adenocarcinoma (subcutaneously) were heated once or twice with a water bath, and the blood flow in the tumor, skin and muscle of the legs was measured with the radioactive microsphere method. Results: The blood flow in control R3230 AC tumors was 23.9 ml/100 g/min. The tumor blood flow increased about 1.5 times in 30 min and then markedly decreased upon heating at 44.5 deg. C for 90 min. In the tumors preheated 16 h earlier at 42.5 deg. C for 60 min, reheating at 44.5 deg. C increased the tumor blood flow by 2.5-fold in 30 min. Contrary to the decline in blood flow following an initial increase during the 44.5 deg. C heating without preheating, the tumor blood flow remained elevated throughout the 90 min reheating at 44.5 deg. C. These results indicated that thermal adaptation or thermotolerance developed in the tumor vasculatures after the preheating at 42.5 deg. C for 60 min. The magnitude of vascular thermal adaptation in the tumors 24 h and 48 h after the preheating, as judged from the changes in blood flow, were smaller than that 16 h after the preheating. Heating at 42.5 deg. C for 60 min induced vascular thermal adaptation also in the skin and muscle, which peaked in 48 h and 24 h, respectively, after the heating. Conclusion: Heating at 42.5 deg. C for 1 h induced vascular thermal adaptation in the R3230 AC tumor, skin, and muscle of rats that peaked 16-48 h after the heating. When the tumor blood vessels were thermally adapted, the tumor blood flow increased upon heating at temperatures that would otherwise reduce the tumor blood flow. Such an increase in tumor blood flow may hinder raising the tumor temperature while it may increase tumor oxygenation.

  11. Thermal stratification and fatigue stress analysis for pressurizer surge line

    International Nuclear Information System (INIS)

    Yu Xiaofei; Zhang Yixiong

    2011-01-01

    Thermal stratification of pressurizer surge line induced by the inside fluid results in the global bending moments, local thermal stresses, unexpected displacements and support loadings of the pipe system. In order to avoid a costly three-dimensional computation, a combined 1D/2D technique has been developed and implemented to analyze the thermal stratification and fatigue stress of pressurize surge line of QINSHAN Phase II Extension Nuclear Power Project in this paper, using the computer codes SYSTUS and ROCOCO. According to the mechanical analysis results of stratification, the maximum stress and cumulative usage factor are obtained. The results indicate that the stress and fatigue intensity considering thermal stratification satisfies RCC-M criterion. (authors)

  12. Adaptive thermal comfort opportunities for dwellings: Providing thermal comfort only when and where needed in dwellings in the Netherlands

    Directory of Open Access Journals (Sweden)

    Noortje Alders

    2016-08-01

    Full Text Available The aim of the research presented in this thesis is to design the characteristics of an Adaptive Thermal Comfort System for Dwellings to achieve a significantly better energy performance whilst not compromising the thermal comfort perception of the occupants. An Adaptive Thermal Comfort System is defined as the whole of passive and active comfort components of the dwelling that dynamically adapts its settings to varying user comfort demands and weather conditions (seasonal, diurnal and hourly depending on the aspects adapted, thus providing comfort only where, when and at the level needed by the user, to improve possibilities of harvesting the environmental energy (e.g. solar gain and outdoor air when available and storing it when abundant. In order to be able to create an Adaptive Thermal Comfort System to save energy knowledge is needed as to where, when, what kind and how much energy is needed to provide the thermal comfort. Therefore, this research aimed to gain insight in the dynamic behaviour of the weather and the occupant and the opportunities to design the characteristics of an Adaptive Thermal Comfort System for Dwellings to achieve a significantly better energy performance whilst not compromising the thermal comfort perception of the occupants answering the main research question;  What are the most efficient strategies for delivering thermal comfort in the residential sector with respect to better energy performances and an increasing demand for flexibility in use and comfort conditions? To answer the main research question three steps were taken, which also represent the three parts of the research: 1. The dynamic information of the factors influencing the thermal heat balance of the dwelling was gathered in order to determine their opportunities for adaptivity. A multidisciplinary approach to Thermal Comfort Systems is followed taking into account the dynamic of occupancy profiles, weather, building physics, HVAC and controls. A

  13. Sleep restriction undermines cardiovascular adaptation during stress, contingent on emotional stability.

    Science.gov (United States)

    Lü, Wei; Hughes, Brian M; Howard, Siobhán; James, Jack E

    2018-02-01

    Sleep loss is associated with increased cardiovascular disease, but physiological mechanisms accounting for this relationship are largely unknown. One possible mechanism is that sleep restriction exerts effects on cardiovascular stress responses, and that these effects vary between individuals. Emotional stability (ES) is a personality trait pertinent to sleep restriction and stress responding. However, no study to date has explored how ES and sleep-restriction interactively affect cardiovascular stress responses or processes of adaptation during stress. The present study sought to investigate the association between ES and impact of sleep restriction on cardiovascular function during stress, with particular regard to the trajectory of cardiovascular function change across time. Ninety female university students completed a laboratory vigilance stress task while undergoing continuous cardiovascular (SBP, DBP, HR, SV, CO, TPR) monitoring, after either a night of partial sleep restriction (40% of habitual sleep duration) or a full night's rest. Individuals high in ES showed stable and adaptive cardiovascular (SBP, SV, CO) responses throughout stress exposure, regardless of sleep. In contrast, individuals low in ES exhibited cardiovascular adaptation during stress exposure while rested, but disrupted adaption while sleep-restricted. These findings suggest that sleep-restriction undermines healthful cardiovascular adaptation to stress for individuals low in ES. Copyright © 2017 Elsevier B.V. All rights reserved.

  14. Modelling of thermal stress in vapor generator supports

    International Nuclear Information System (INIS)

    Halpert, S.; Vazquez, L.

    1997-01-01

    To assure safety and availability of a nuclear power plant components or equipment stress analysis are done. When thermal loads are involved it's necessary to know the temperature field of the component or equipment. This paper describes the structural analysis of a steam generator lug with thermal load including the model used for computer simulation and presents the evolution of the temperature profile, the stress intensity and principal stress during start up and shut down of a nuclear power reactor. Temperature field obtained from code calculation show good agreement with the experimental data while stress analysis results are in agreement with a preview estimation. (author) [es

  15. Stress inoculation training supported by physiology-driven adaptive virtual reality stimulation.

    Science.gov (United States)

    Popović, Sinisa; Horvat, Marko; Kukolja, Davor; Dropuljić, Branimir; Cosić, Kresimir

    2009-01-01

    Significant proportion of psychological problems related to combat stress in recent large peacekeeping operations underscores importance of effective methods for strengthening the stress resistance of military personnel. Adaptive control of virtual reality (VR) stimulation, based on estimation of the subject's emotional state from physiological signals, may enhance existing stress inoculation training (SIT). Physiology-driven adaptive VR stimulation can tailor the progress of stressful stimuli delivery to the physiological characteristics of each individual, which is indicated for improvement in stress resistance. Therefore, following an overview of SIT and its applications in the military setting, generic concept of physiology-driven adaptive VR stimulation is presented in the paper. Toward the end of the paper, closed-loop adaptive control strategy applicable to SIT is outlined.

  16. Occupants' adaptive responses and perception of thermal environment in naturally conditioned university classrooms

    Energy Technology Data Exchange (ETDEWEB)

    Yao, Runming [The School of Construction Management and Engineering, The University of Reading, Whiteknights, PO Box 219, Reading RG6 6AW (United Kingdom); The Faculty of Urban Construction and Environmental Engineering, Chongqing University, Chongqing 400042 (China); Liu, Jing [The School of Construction Management and Engineering, The University of Reading, Whiteknights, PO Box 219, Reading RG6 6AW (United Kingdom); Li, Baizhan [The Faculty of Urban Construction and Environmental Engineering, Chongqing University, Chongqing 400042 (China); Key Laboratory of the Three Gorges Reservoir Region' s Eco-Environment (Ministry of Education), Chongqing University, Chongqing 400042 (China)

    2010-03-15

    A year-long field study of the thermal environment in university classrooms was conducted from March 2005 to May 2006 in Chongqing, China. This paper presents the occupants' thermal sensation votes and discusses the occupants' adaptive response and perception of the thermal environment in a naturally conditioned space. Comparisons between the Actual Mean Vote (AMV) and Predicted Mean Vote (PMV) have been made as well as between the Actual Percentage of Dissatisfied (APD) and Predicted Percentage of Dissatisfied (PPD). The adaptive thermal comfort zone for the naturally conditioned space for Chongqing, which has hot summer and cold winter climatic characteristics, has been proposed based on the field study results. The Chongqing adaptive comfort range is broader than that of the ASHRAE Standard 55-2004 in general, but in the extreme cold and hot months, it is narrower. The thermal conditions in classrooms in Chongqing in summer and winter are severe. Behavioural adaptation such as changing clothing, adjusting indoor air velocity, taking hot/cold drinks, etc., as well as psychological adaptation, has played a role in adapting to the thermal environment. (author)

  17. Non-linear elastic thermal stress analysis with phase changes

    International Nuclear Information System (INIS)

    Amada, S.; Yang, W.H.

    1978-01-01

    The non-linear elastic, thermal stress analysis with temperature induced phase changes in the materials is presented. An infinite plate (or body) with a circular hole (or tunnel) is subjected to a thermal loading on its inner surface. The peak temperature around the hole reaches beyond the melting point of the material. The non-linear diffusion equation is solved numerically using the finite difference method. The material properties change rapidly at temperatures where the change of crystal structures and solid-liquid transition occur. The elastic stresses induced by the transient non-homogeneous temperature distribution are calculated. The stresses change remarkably when the phase changes occur and there are residual stresses remaining in the plate after one cycle of thermal loading. (Auth.)

  18. Response of heat shock protein genes of the oriental fruit moth under diapause and thermal stress reveals multiple patterns dependent on the nature of stress exposure.

    Science.gov (United States)

    Zhang, Bo; Peng, Yu; Zheng, Jincheng; Liang, Lina; Hoffmann, Ary A; Ma, Chun-Sen

    2016-07-01

    Heat shock protein gene (Hsp) families are thought to be important in thermal adaptation, but their expression patterns under various thermal stresses have still been poorly characterized outside of model systems. We have therefore characterized Hsp genes and their stress responses in the oriental fruit moth (OFM), Grapholita molesta, a widespread global orchard pest, and compared patterns of expression in this species to that of other insects. Genes from four Hsp families showed variable expression levels among tissues and developmental stages. Members of the Hsp40, 70, and 90 families were highly expressed under short exposures to heat and cold. Expression of Hsp40, 70, and Hsc70 family members increased in OFM undergoing diapause, while Hsp90 was downregulated. We found that there was strong sequence conservation of members of large Hsp families (Hsp40, Hsp60, Hsp70, Hsc70) across taxa, but this was not always matched by conservation of expression patterns. When the large Hsps as well as small Hsps from OFM were compared under acute and ramping heat stress, two groups of sHsps expression patterns were apparent, depending on whether expression increased or decreased immediately after stress exposure. These results highlight potential differences in conservation of function as opposed to sequence in this gene family and also point to Hsp genes potentially useful as bioindicators of diapause and thermal stress in OFM.

  19. Thermal properties of graphene under tensile stress

    Science.gov (United States)

    Herrero, Carlos P.; Ramírez, Rafael

    2018-05-01

    Thermal properties of graphene display peculiar characteristics associated to the two-dimensional nature of this crystalline membrane. These properties can be changed and tuned in the presence of applied stresses, both tensile and compressive. Here, we study graphene monolayers under tensile stress by using path-integral molecular dynamics (PIMD) simulations, which allows one to take into account quantization of vibrational modes and analyze the effect of anharmonicity on physical observables. The influence of the elastic energy due to strain in the crystalline membrane is studied for increasing tensile stress and for rising temperature (thermal expansion). We analyze the internal energy, enthalpy, and specific heat of graphene, and compare the results obtained from PIMD simulations with those given by a harmonic approximation for the vibrational modes. This approximation turns out to be precise at low temperatures, and deteriorates as temperature and pressure are increased. At low temperature, the specific heat changes as cp˜T for stress-free graphene, and evolves to a dependence cp˜T2 as the tensile stress is increased. Structural and thermodynamic properties display non-negligible quantum effects, even at temperatures higher than 300 K. Moreover, differences in the behavior of the in-plane and real areas of graphene are discussed, along with their associated properties. These differences show up clearly in the corresponding compressibility and thermal expansion coefficient.

  20. Microbial dinitrogen fixation in coral holobionts exposed to thermal stress and bleaching.

    Science.gov (United States)

    Cardini, Ulisse; van Hoytema, Nanne; Bednarz, Vanessa N; Rix, Laura; Foster, Rachel A; Al-Rshaidat, Mamoon M D; Wild, Christian

    2016-09-01

    Coral holobionts (i.e., coral-algal-prokaryote symbioses) exhibit dissimilar thermal sensitivities that may determine which coral species will adapt to global warming. Nonetheless, studies simultaneously investigating the effects of warming on all holobiont members are lacking. Here we show that exposure to increased temperature affects key physiological traits of all members (herein: animal host, zooxanthellae and diazotrophs) of both Stylophora pistillata and Acropora hemprichii during and after thermal stress. S. pistillata experienced severe loss of zooxanthellae (i.e., bleaching) with no net photosynthesis at the end of the experiment. Conversely, A. hemprichii was more resilient to thermal stress. Exposure to increased temperature (+ 6°C) resulted in a drastic increase in daylight dinitrogen (N2 ) fixation, particularly in A. hemprichii (threefold compared with controls). After the temperature was reduced again to in situ levels, diazotrophs exhibited a reversed diel pattern of activity, with increased N2 fixation rates recorded only in the dark, particularly in bleached S. pistillata (twofold compared to controls). Concurrently, both animal hosts, but particularly bleached S. pistillata, reduced both organic matter release and heterotrophic feeding on picoplankton. Our findings indicate that physiological plasticity by coral-associated diazotrophs may play an important role in determining the response of coral holobionts to ocean warming. © 2016 Society for Applied Microbiology and John Wiley & Sons Ltd.

  1. Passenger thermal perceptions, thermal comfort requirements, and adaptations in short- and long-haul vehicles.

    Science.gov (United States)

    Lin, Tzu-Ping; Hwang, Ruey-Lung; Huang, Kuo-Tsang; Sun, Chen-Yi; Huang, Ying-Che

    2010-05-01

    While thermal comfort in mass transportation vehicles is relevant to service quality and energy consumption, benchmarks for such comfort that reflect the thermal adaptations of passengers are currently lacking. This study reports a field experiment involving simultaneous physical measurements and a questionnaire survey, collecting data from 2,129 respondents, that evaluated thermal comfort in short- and long-haul buses and trains. Experimental results indicate that high air temperature, strong solar radiation, and low air movement explain why passengers feel thermally uncomfortable. The overall insulation of clothing worn by passengers and thermal adaptive behaviour in vehicles differ from those in their living and working spaces. Passengers in short-haul vehicles habitually adjust the air outlets to increase thermal comfort, while passengers in long-haul vehicles prefer to draw the drapes to reduce discomfort from extended exposure to solar radiation. The neutral temperatures for short- and long-haul vehicles are 26.2 degrees C and 27.4 degrees C, while the comfort zones are 22.4-28.9 degrees C and 22.4-30.1 degrees C, respectively. The results of this study provide a valuable reference for practitioners involved in determining the adequate control and management of in-vehicle thermal environments, as well as facilitating design of buses and trains, ultimately contributing to efforts to achieve a balance between the thermal comfort satisfaction of passengers and energy conserving measures for air-conditioning in mass transportation vehicles.

  2. Thermal Adaptation Methods of Urban Plaza Users in Asia's Hot-Humid Regions: A Taiwan Case Study.

    Science.gov (United States)

    Wu, Chen-Fa; Hsieh, Yen-Fen; Ou, Sheng-Jung

    2015-10-27

    Thermal adaptation studies provide researchers great insight to help understand how people respond to thermal discomfort. This research aims to assess outdoor urban plaza conditions in hot and humid regions of Asia by conducting an evaluation of thermal adaptation. We also propose that questionnaire items are appropriate for determining thermal adaptation strategies adopted by urban plaza users. A literature review was conducted and first hand data collected by field observations and interviews used to collect information on thermal adaptation strategies. Item analysis--Exploratory Factor Analysis (EFA) and Confirmatory Factor Analysis (CFA)--were applied to refine the questionnaire items and determine the reliability of the questionnaire evaluation procedure. The reliability and validity of items and constructing process were also analyzed. Then, researchers facilitated an evaluation procedure for assessing the thermal adaptation strategies of urban plaza users in hot and humid regions of Asia and formulated a questionnaire survey that was distributed in Taichung's Municipal Plaza in Taiwan. Results showed that most users responded with behavioral adaptation when experiencing thermal discomfort. However, if the thermal discomfort could not be alleviated, they then adopted psychological strategies. In conclusion, the evaluation procedure for assessing thermal adaptation strategies and the questionnaire developed in this study can be applied to future research on thermal adaptation strategies adopted by urban plaza users in hot and humid regions of Asia.

  3. Thermal mechanical stress modeling of GCtM seals

    Energy Technology Data Exchange (ETDEWEB)

    Dai, Steve Xunhu [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Chambers, Robert [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States)

    2015-09-01

    Finite-element thermal stress modeling at the glass-ceramic to metal (GCtM) interface was conducted assuming heterogeneous glass-ceramic microstructure. The glass-ceramics were treated as composites consisting of high expansion silica crystalline phases dispersed in a uniform residual glass. Interfacial stresses were examined for two types of glass-ceramics. One was designated as SL16 glass -ceramic, owing to its step-like thermal strain curve with an overall coefficient of thermal expansion (CTE) at 16 ppm/ºC. Clustered Cristobalite is the dominant silica phase in SL16 glass-ceramic. The other, designated as NL16 glass-ceramic, exhibited clusters of mixed Cristobalite and Quartz and showed a near-linear thermal strain curve with a same CTE value.

  4. Adaptive Thermal Comfort in Japanese Houses during the Summer Season: Behavioral Adaptation and the Effect of Humidity

    Directory of Open Access Journals (Sweden)

    Hom B. Rijal

    2015-09-01

    Full Text Available In order to clarify effect of humidity on the room temperatures reported to be comfortable, an occupant thermal comfort and behavior survey was conducted for five summers in the living rooms and bedrooms of residences in the Kanto region of Japan. We have collected 13,525 thermal comfort votes from over 239 residents of 120 homes, together with corresponding measurements of room temperature and humidity of the air. The residents were generally well-satisfied with the thermal environment of their houses, with or without the use of air-conditioning, and thus were well-adapted to their thermal conditions. The humidity was found to have very little direct effect on the comfort temperature. However, the comfort temperature was strongly related to the reported skin moisture. Behavioral adaptation such as window opening and fan use increase air movement and improve thermal comfort.

  5. A numerical analysis method on thermal and shrinkage stress of concrete

    International Nuclear Information System (INIS)

    Takiguchi, Katsuki; Hotta, Hisato

    1991-01-01

    Thermal stress often causes cracks in large scale concrete such as that for dam construction. The drying shrinkage of concrete causes cracks in concrete structures. These thermal stress and drying shrinkage stress may be the main reasons cracks occur in concrete, however there is few research which dealt with both stresses together. The problems on the thermal stress and the drying shrinkage are not independent, and should be dealt with together, because both temperature and water content of concrete affect hydration reaction, and the degree of hydration determines all the characteristics of concrete at early age. In this study, the degree of hydration is formulated experimentally, and a numerical stress analysis method taking the hydration reaction in consideration is presented. The formulation of the rate of hydration reaction, the method of analyzing thermal and drying shrinkage stresses, the analytical results for a concrete column and the influence that continuous load exerted to the tensile strength of concrete are reported. The relatively high stress nearly equal to the tensile strength of concrete arises near the surface. (K.I.)

  6. The application of fracture mechanics in thermally stressed structures

    International Nuclear Information System (INIS)

    Cesari, F.; Maitan, A.; Hellen, T.K.

    1981-03-01

    There is considerable interest in calculating stress intensity factors at crack tips in thermally stressed structures, particularly in the power generation industry where the safe operation of both conventional and nuclear plant is founded on rigorous safety cases. Analytical methods to study such problems are of limited scope, although they can be extended by introducing numerical techniques. Purpose built numerical methods, however, offer a much greater and more accurate solution capability and in particular the finite element method is well advanced. Such methods are described, including how stress intensity factors can be obtained from the finite element results. They are then applied to a range of thermally stressed problems including plates with central cracks and cylinders with axial and circumferential cracks. Both steady state and transient temperature distributions arising from typical thermal shocks are considered. (author)

  7. Stress, Shock, and Adaptation in the Twentieth Century

    DEFF Research Database (Denmark)

    Leese, Peter

    2016-01-01

    Review article on: David Cantor and Edmund Ramsden, eds. Stress, Shock, and Adaptation in the Twentieth Century. Rochester Studies in Medical History. Rochester, N.Y.: University of Rochester Press, 2014. vi + 367 pp. Ill. $125.00 (978-1-58046-476-5).......Review article on: David Cantor and Edmund Ramsden, eds. Stress, Shock, and Adaptation in the Twentieth Century. Rochester Studies in Medical History. Rochester, N.Y.: University of Rochester Press, 2014. vi + 367 pp. Ill. $125.00 (978-1-58046-476-5)....

  8. Mitigation method of thermal transient stress by thermalhydraulic-structure total analysis

    International Nuclear Information System (INIS)

    Kasahara, Naoto; Jinbo, Masakazu; Hosogai, Hiromi

    2003-01-01

    This study proposes a rational evaluation and mitigation method of thermal transient loads in fast reactor components by utilizing relationships among plant system parameters and stresses induced by thermal transients of plants. A thermalhydraulic-structure total analysis procedure helps us to grasp relationship among system parameters and thermal stresses. Furthermore, it enables mitigation of thermal transient loads by adjusting system parameters. In order to overcome huge computations, a thermalhydraulic-structure total analysis code and the Design of Experiments methodology are utilized. The efficiency of the proposed mitigation method is validated through thermal stress evaluation of an intermediate heat exchanger in Japanese demonstration fast reactor. (author)

  9. The rgg0182 gene encodes a transcriptional regulator required for the full Streptococcus thermophilus LMG18311 thermal adaptation.

    Science.gov (United States)

    Henry, Romain; Bruneau, Emmanuelle; Gardan, Rozenn; Bertin, Stéphane; Fleuchot, Betty; Decaris, Bernard; Leblond-Bourget, Nathalie

    2011-10-07

    Streptococcus thermophilus is an important starter strain for the production of yogurt and cheeses. The analysis of sequenced genomes of four strains of S. thermophilus indicates that they contain several genes of the rgg familly potentially encoding transcriptional regulators. Some of the Rgg proteins are known to be involved in bacterial stress adaptation. In this study, we demonstrated that Streptococcus thermophilus thermal stress adaptation required the rgg0182 gene which transcription depends on the culture medium and the growth temperature. This gene encoded a protein showing similarity with members of the Rgg family transcriptional regulator. Our data confirmed that Rgg0182 is a transcriptional regulator controlling the expression of its neighboring genes as well as chaperones and proteases encoding genes. Therefore, analysis of a Δrgg0182 mutant revealed that this protein played a role in the heat shock adaptation of Streptococcus thermophilus LMG18311. These data showed the importance of the Rgg0182 transcriptional regulator on the survival of S. thermophilus during dairy processes and more specifically during changes in temperature.

  10. The rgg0182 gene encodes a transcriptional regulator required for the full Streptococcus thermophilus LMG18311 thermal adaptation

    Directory of Open Access Journals (Sweden)

    Bertin Stéphane

    2011-10-01

    Full Text Available Abstract Background Streptococcus thermophilus is an important starter strain for the production of yogurt and cheeses. The analysis of sequenced genomes of four strains of S. thermophilus indicates that they contain several genes of the rgg familly potentially encoding transcriptional regulators. Some of the Rgg proteins are known to be involved in bacterial stress adaptation. Results In this study, we demonstrated that Streptococcus thermophilus thermal stress adaptation required the rgg0182 gene which transcription depends on the culture medium and the growth temperature. This gene encoded a protein showing similarity with members of the Rgg family transcriptional regulator. Our data confirmed that Rgg0182 is a transcriptional regulator controlling the expression of its neighboring genes as well as chaperones and proteases encoding genes. Therefore, analysis of a Δrgg0182 mutant revealed that this protein played a role in the heat shock adaptation of Streptococcus thermophilus LMG18311. Conclusions These data showed the importance of the Rgg0182 transcriptional regulator on the survival of S. thermophilus during dairy processes and more specifically during changes in temperature.

  11. Thermal stresses in composite tubes using complementary virtual work

    Science.gov (United States)

    Hyer, M. W.; Cooper, D. E.

    1988-01-01

    This paper addresses the computation of thermally induced stresses in layered, fiber-reinforced composite tubes subjected to a circumferential gradient. The paper focuses on using the principle of complementary virtual work, in conjunction with a Ritz approximation to the stress field, to study the influence on the predicted stresses of including temperature-dependent material properties. Results indicate that the computed values of stress are sensitive to the temperature dependence of the matrix-direction compliance and matrix-direction thermal expansion in the plane of the lamina. There is less sensitivity to the temperature dependence of the other material properties.

  12. Lipid biomarkers in Symbiodinium dinoflagellates: new indicators of thermal stress

    KAUST Repository

    Kneeland, J.

    2013-08-30

    Lipid content and fatty acid profiles of corals and their dinoflagellate endosymbionts are known to vary in response to high-temperature stress. To better understand the heat-stress response in these symbionts, we investigated cultures of Symbiodinium goreauii type C1 and Symbiodinium sp. clade subtype D1 grown under a range of temperatures and durations. The predominant lipids produced by Symbiodinium are palmitic (C16) and stearic (C18) saturated fatty acids and their unsaturated analogs, the polyunsaturated fatty acid docosahexaenoic acid (C22:6, n-3; DHA), and a variety of sterols. Prolonged exposure to high temperature causes the relative amount of unsaturated acids within the C18 fatty acids in Symbiodinium tissue to decrease. Thermal stress also causes a decrease in abundance of fatty acids relative to sterols, as well as the more specific ratio of DHA to an algal 4-methyl sterol. These shifts in fatty acid unsaturation and fatty acid-to-sterol ratios are common to both types C1 and D1, but the apparent thermal threshold of lipid changes is lower for type C1. This work indicates that ratios among free fatty acids and sterols in Symbiodinium can be used as sensitive indicators of thermal stress. If the Symbiodinium lipid stress response is unchanged in hospite, the algal heat-stress biomarkers we have identified could be measured to detect thermal stress within the coral holobiont. These results provide new insights into the potential role of lipids in the overall Symbiodinium thermal stress response. © 2013 Springer-Verlag Berlin Heidelberg.

  13. A Nonlinear Adaptive Filter for Gyro Thermal Bias Error Cancellation

    Science.gov (United States)

    Galante, Joseph M.; Sanner, Robert M.

    2012-01-01

    Deterministic errors in angular rate gyros, such as thermal biases, can have a significant impact on spacecraft attitude knowledge. In particular, thermal biases are often the dominant error source in MEMS gyros after calibration. Filters, such as J\\,fEKFs, are commonly used to mitigate the impact of gyro errors and gyro noise on spacecraft closed loop pointing accuracy, but often have difficulty in rapidly changing thermal environments and can be computationally expensive. In this report an existing nonlinear adaptive filter is used as the basis for a new nonlinear adaptive filter designed to estimate and cancel thermal bias effects. A description of the filter is presented along with an implementation suitable for discrete-time applications. A simulation analysis demonstrates the performance of the filter in the presence of noisy measurements and provides a comparison with existing techniques.

  14. Thermal stress in flexible interdigital transducers with anisotropic electroactive cellulose substrates

    Science.gov (United States)

    Yoon, Sean J.; Kim, Jung Woong; Kim, Hyun Chan; Kang, Jinmo; Kim, Jaehwan

    2017-12-01

    Thermal stress in flexible interdigital transducers a reliability concern in the development of flexible devices, which may lead to interface delamination, stress voiding and plastic deformation. In this paper, a mathematical model is presented to investigate the effect of material selections on the thermal stress in interdigital transducers. We modified the linear relationships in the composite materials theory with the effect of high curvature, anisotropic substrate and small substrate thickness. We evaluated the thermal stresses of interdigital transducers, fabricated with various electrodes, insulators and substrate materials for the comparison. The results show that, among various insulators, organic polymer developed the highest stress level while oxide showed the lowest stress level. Aluminium shows a higher stress level and curvature as an electrode than gold. As substrate materials, polyimide and electroactive cellulose show similar stress levels except the opposite sign convention to each other. Polyimide shows positive curvatures while electroactive cellulose shows negative curvatures, which is attributed to the stress and thermal expansion state of the metal/insulator composite. The results show that the insulator is found to be responsible for the confinement across the metal lines while the substrate is responsible for the confinement along the metal lines.

  15. Thermal adaptation in North American cicadas (Hemiptera: Cicadidae).

    Science.gov (United States)

    Sanborn, Allen F; Heath, James E; Heath, Maxine S; Phillips, Polly K

    2017-10-01

    We determine and summarize the thermal responses for 118 species and subspecies of North American cicadas representing more than 50 years of fieldwork and experimentation. We investigate the role that habitat and behavior have on the thermal adaptation of the North American cicadas. There are general patterns of increasing thermal responses in warmer floristic provinces and increasing maximum potential temperature within a habitat. Altitude shows an inverse relationship with thermal responses. Comparison of thermal responses of species emerging early or late in the season within the same habitat show increases in the thermal responses along with the increasing environmental temperatures late in the summer. However, behavior, specifically the use of endothermy as a thermoregulatory strategy, can influence the values determined in a particular habitat. Subspecies generally do not differ in their thermal tolerances and thermal tolerances are consistent within a species over distances of more than 7600km. Copyright © 2017 Elsevier Ltd. All rights reserved.

  16. Coral thermal tolerance: tuning gene expression to resist thermal stress.

    Directory of Open Access Journals (Sweden)

    Anthony J Bellantuono

    Full Text Available The acclimatization capacity of corals is a critical consideration in the persistence of coral reefs under stresses imposed by global climate change. The stress history of corals plays a role in subsequent response to heat stress, but the transcriptomic changes associated with these plastic changes have not been previously explored. In order to identify host transcriptomic changes associated with acquired thermal tolerance in the scleractinian coral Acropora millepora, corals preconditioned to a sub-lethal temperature of 3°C below bleaching threshold temperature were compared to both non-preconditioned corals and untreated controls using a cDNA microarray platform. After eight days of hyperthermal challenge, conditions under which non-preconditioned corals bleached and preconditioned corals (thermal-tolerant maintained Symbiodinium density, a clear differentiation in the transcriptional profiles was revealed among the condition examined. Among these changes, nine differentially expressed genes separated preconditioned corals from non-preconditioned corals, with 42 genes differentially expressed between control and preconditioned treatments, and 70 genes between non-preconditioned corals and controls. Differentially expressed genes included components of an apoptotic signaling cascade, which suggest the inhibition of apoptosis in preconditioned corals. Additionally, lectins and genes involved in response to oxidative stress were also detected. One dominant pattern was the apparent tuning of gene expression observed between preconditioned and non-preconditioned treatments; that is, differences in expression magnitude were more apparent than differences in the identity of genes differentially expressed. Our work revealed a transcriptomic signature underlying the tolerance associated with coral thermal history, and suggests that understanding the molecular mechanisms behind physiological acclimatization would be critical for the modeling of reefs

  17. Thermal Stress Analysis of Medium-Voltage Converters for Smart Transformers

    DEFF Research Database (Denmark)

    Andresen, Markus; Ma, Ke; De Carne, Giovanni

    2017-01-01

    . To address this concern, this work conducts thermal stress analysis for a modular multilevel converter (MMC), which is a promising solution for the medium voltage stage of the ST. The focus is put on the mission profiles of the transformer and the impact on the thermal stress of power semiconductor devices......A smart transformer (ST) can take over an important managing role in the future electrical distribution grid system and can provide many advanced grid services compared to the traditional transformer. However, the risk is that the advanced functionality is balanced out by a lower reliability....... Normal operation at different power levels and medium voltage grid faults in a feeder fed by a traditional transformer are considered as well as the electrical and the thermal stress of the disconnection and the reconnection procedures. For the validation, the thermal stress of one MMC cell is reproduced...

  18. Adaptation and survival of plants in high stress habitats via fungal endophyte conferred stress tolerance

    Science.gov (United States)

    Rodriguez, Rusty J.; Woodward, Claire; Redman, Regina S.

    2010-01-01

    From the Arctic to the Antarctic, plants thrive in diverse habitats that impose different levels of adaptive pressures depending on the type and degree of biotic and abiotic stresses inherent to each habitat (Stevens, 1989). At any particular location, the abundance and distribution of individual plant species vary tremendously and is theorized to be based on the ability to tolerate a wide range of edaphic conditions and habitat-specific stresses (Pianka, 1966). The ability of individual plant species to thrive in diverse habitats is commonly referred to as phenotypic plasticity and is thought to involve adaptations based on changes in the plant genome (Givnish, 2002; Pan et al., 2006; Robe and Griffiths, 2000; Schurr et al., 2006). Habitats that impose high levels of abiotic stress are typically colonized with fewer plant species compared to habitats imposing low levels of stress. Moreover, high stress habitats have decreased levels of plant abundance compared to low stress habitats even though these habitats may occur in close proximity to one another (Perelman et al., 2007). This is particularly interesting because all plants are known to perceive, transmit signals, and respond to abiotic stresses such as drought, heat, and salinity (Bartels and Sunkar, 2005; Bohnert et al., 1995). Although there has been extensive research performed to determine the genetic, molecular, and physiological bases of how plants respond to and tolerate stress, the nature of plant adaptation to high stress habitats remains unresolved (Leone et al., 2003; Maggio et al., 2003; Tuberosa et al., 2003). However, recent evidence indicates that a ubiquitous aspect of plant biology (fungal symbiosis) is involved in the adaptation and survival of at least some plants in high stress habitats (Rodriguez et al., 2008).

  19. Location-specific responses to thermal stress in larvae of the reef-building coral Montastraea faveolata.

    Directory of Open Access Journals (Sweden)

    Nicholas R Polato

    2010-06-01

    Full Text Available The potential to adapt to a changing climate depends in part upon the standing genetic variation present in wild populations. In corals, the dispersive larval phase is particularly vulnerable to the effects of environmental stress. Larval survival and response to stress during dispersal and settlement will play a key role in the persistence of coral populations.To test the hypothesis that larval transcription profiles reflect location-specific responses to thermal stress, symbiont-free gametes from three to four colonies of the scleractinian coral Montastraea faveolata were collected from Florida and Mexico, fertilized, and raised under mean and elevated (up 1 to 2 degrees C above summer mean temperatures. These locations have been shown to exchange larvae frequently enough to prevent significant differentiation of neutral loci. Differences among 1,310 unigenes were simultaneously characterized using custom cDNA microarrays, allowing investigation of gene expression patterns among larvae generated from wild populations under stress. Results show both conserved and location-specific variation in key processes including apoptosis, cell structuring, adhesion and development, energy and protein metabolism, and response to stress, in embryos of a reef-building coral.These results provide first insights into location-specific variation in gene expression in the face of gene flow, and support the hypothesis that coral host genomes may house adaptive potential needed to deal with changing environmental conditions.

  20. Impact of thermal stress on evolutionary trajectories of pathogen resistance in three-spined stickleback (Gasterosteus aculeatus).

    Science.gov (United States)

    Schade, Franziska M; Shama, Lisa N S; Wegner, K Mathias

    2014-07-26

    Pathogens are a major regulatory force for host populations, especially under stressful conditions. Elevated temperatures may enhance the development of pathogens, increase the number of transmission stages, and can negatively influence host susceptibility depending on host thermal tolerance. As a net result, this can lead to a higher prevalence of epidemics during summer months. These conditions also apply to marine ecosystems, where possible ecological impacts and the population-specific potential for evolutionary responses to changing environments and increasing disease prevalence are, however, less known. Therefore, we investigated the influence of thermal stress on the evolutionary trajectories of disease resistance in three marine populations of three-spined sticklebacks Gasterosteus aculeatus by combining the effects of elevated temperature and infection with a bacterial strain of Vibrio sp. using a common garden experiment. We found that thermal stress had an impact on fish weight and especially on survival after infection after only short periods of thermal acclimation. Environmental stress reduced genetic differentiation (QST) between populations by releasing cryptic within-population variation. While life history traits displayed positive genetic correlations across environments with relatively weak genotype by environment interactions (GxE), environmental stress led to negative genetic correlations across environments in pathogen resistance. This reversal of genetic effects governing resistance is probably attributable to changing environment-dependent virulence mechanisms of the pathogen interacting differently with host genotypes, i.e. GPathogenxGHostxE or (GPathogenxE)x(GHostxE) interactions, rather than to pure host genetic effects, i.e. GHostxE interactions. To cope with climatic changes and the associated increase in pathogen virulence, host species require wide thermal tolerances and pathogen-resistant genotypes. The higher resistance we found

  1. Thermal stresses in hexagonal materials - heat treatment influence on their mechanical behaviour

    International Nuclear Information System (INIS)

    Gloaguen, D.; Freour, S.; Guillen, R.; Royer, J.; Francois, M.

    2004-01-01

    Internal stresses due to anisotropic thermal and plastic properties were investigated in rolled zirconium and titanium. The thermal stresses induced by a cooling process were predicted using a self-consistent model and compared with experimental results obtained by X-ray diffraction. The study of the elastoplastic response during uniaxial loading was performed along the rolling and the transverse direction of the sheet, considering the influence of the texture and the thermal stresses on the mechanical behaviour. An approach in order to determine the thermal behaviour of phases embedded in two-phase materials is also presented. For zirconium, the residual stresses due to thermal anisotropy are rather important (equivalent to 35% of the yield stress) and consequently they play an important role on the elastoplastic transition contrary to titanium. The study of two-phase material shows the influence and the interaction of the second phase on the thermal behaviour in the studied phase

  2. Physiological adaptation to recurrent social stress of extraversion.

    Science.gov (United States)

    Lu, Wei; Wang, Zhenhong

    2017-02-01

    The present studies examined the influence of extraversion on physiological reactivity, recovery, and physiological habituation-sensitization to repeated social stressors. In Study 1, subjective and physiological data were collected from 97 college students who were categorized as high (n = 51) and low (n = 46) on extraversion (NEO-FFI) across five laboratory stages: baseline, stress 1, poststress 1, stress 2, and poststress 2. Results indicated high extraversion (HE) participants exhibited relative lesser heart rate (HR) reactivity and respiratory sinus arrhythmia (RSA) withdrawals to, and more complete HR and RSA recovery after the first social stress, and also exhibited relative lesser HR reactivity to the second social stress. When repeatedly exposed to a social stressor, HE participants showed pronounced systolic blood pressure (SBP) adaptation, low extraversion (LE) participants displayed diastolic blood pressure (DBP) sensitization. In Study 2, data were collected from another 78 participants (HE: n = 40, LE: n = 38) across the same laboratory stages with speech performance videotaped. After controlling for the speech styles, Study 2 found the same HR response and SBP/DBP adaptation pattern across extraversion groups to social stress as Study 1 but not RSA reactivity. These findings suggest extraverts exhibit more adaptive physiological reactivity to recurrent social stressors, which thus might benefit their health. © 2016 Society for Psychophysiological Research.

  3. Adaptive Restoration of Airborne Daedalus AADS1268 ATM Thermal Data

    International Nuclear Information System (INIS)

    D. Yuan; E. Doak; P. Guss; A. Will

    2002-01-01

    To incorporate the georegistration and restoration processes into airborne data processing in support of U.S. Department of Energy's nuclear emergency response task, we developed an adaptive restoration filter for airborne Daedalus AADS1268 ATM thermal data based on the Wiener filtering theory. Preliminary assessment shows that this filter enhances the detectability of small weak thermal anomalies in AADS1268 thermal images

  4. Thermal-stress fatigue behavior of twenty-six superalloys

    Science.gov (United States)

    Bizon, P. T.; Spera, D. A.

    1976-01-01

    The comparative thermal-stress fatigue resistances of 26 nickeland cobalt-base alloys were determined by fluidized bed tests. Cycles to cracking differed by almost three orders of magnitude for these materials, with directional solidification and surface protection showing definite benefit. The alloy-coating combination with the highest thermal-stress fatigue resistance was directionally solidified NASA TAZ-8A with an RT-SP coating. Its oxidation resistance was also excellent, showing approximately a 1/2 percent weight loss after 14,000 fluidized bed cycles.

  5. Openness to experience and adapting to change: Cardiovascular stress habituation to change in acute stress exposure.

    Science.gov (United States)

    Ó Súilleabháin, Páraic S; Howard, Siobhán; Hughes, Brian M

    2018-05-01

    Underlying psychophysiological mechanisms of effect linking openness to experience to health outcomes, and particularly cardiovascular well-being, are unknown. This study examined the role of openness in the context of cardiovascular responsivity to acute psychological stress. Continuous cardiovascular response data were collected for 74 healthy young female adults across an experimental protocol, including differing counterbalanced acute stressors. Openness was measured via self-report questionnaire. Analysis of covariance revealed openness was associated with systolic blood pressure (SBP; p = .016), and diastolic blood pressure (DBP; p = .036) responsivity across the protocol. Openness was also associated with heart rate (HR) responding to the initial stress exposure (p = .044). Examination of cardiovascular adaptation revealed that higher openness was associated with significant SBP (p = .001), DBP (p = .009), and HR (p = .002) habituation in response to the second differing acute stress exposure. Taken together, the findings suggest persons higher in openness are characterized by an adaptive cardiovascular stress response profile within the context of changing acute stress exposures. This study is also the first to demonstrate individual differences in cardiovascular adaptation across a protocol consisting of differing stress exposures. More broadly, this research also suggests that future research may benefit from conceptualizing an adaptive fitness of openness within the context of change. In summary, the present study provides evidence that higher openness stimulates short-term stress responsivity, while ensuring cardiovascular habituation to change in stress across time. © 2017 Society for Psychophysiological Research.

  6. Employee stress management: An examination of adaptive and maladaptive coping strategies on employee health.

    Science.gov (United States)

    Holton, M Kim; Barry, Adam E; Chaney, J Don

    2015-01-01

    Employees commonly report feeling stressed at work. Examine how employees cope with work and personal stress, whether their coping strategies are adaptive (protective to health) or maladaptive (detrimental to health), and if the manner in which employees cope with stress influences perceived stress management. In this cross-sectional study, a random sample of 2,500 full-time university non-student employees (i.e. faculty, salaried professionals, and hourly non-professionals) were surveyed on health related behaviors including stress and coping. Approximately 1,277 completed the survey (51% ). Hierarchical logistic regression was used to assess the ability of adaptive and maladaptive coping strategies to predict self-reported stress management, while controlling for multiple demographic variables. Over half of employees surveyed reported effective stress management. Most frequently used adaptive coping strategies were communication with friend/family member and exercise, while most frequently used maladaptive coping strategies were drinking alcohol and eating more than usual. Both adaptive and maladaptive coping strategies made significant (p stress management. Only adaptive coping strategies (B = 0.265) predicted whether someone would self-identify as effectively managing stress. Use of maladaptive coping strategies decreased likelihood of self-reporting effective stress management. Actual coping strategies employed may influence employees' perceived stress management. Adaptive coping strategies may be more influential than maladaptive coping strategies on perceived stress management. Results illustrate themes for effective workplace stress management programs. Stress management programs focused on increasing use of adaptive coping may have a greater impact on employee stress management than those focused on decreasing use of maladaptive coping. Coping is not only a reaction to stressful experiences but also a consequence of coping resources. Thereby increasing the

  7. Adaptive capability as indicated by endocrine and biochemical responses of Malpura ewes subjected to combined stresses (thermal and nutritional) in a semi-arid tropical environment

    Science.gov (United States)

    Sejian, Veerasamy; Maurya, Vijai P.; Naqvi, Sayeed M. K.

    2010-11-01

    A study was conducted to assess the effect of combined stresses (thermal and nutritional) on endocrine and biochemical responses in Malpura ewes. Twenty eight adult Malpura ewes (average body weight 33.56 kg) were used in the present study. The ewes were divided into four groups viz., GI ( n = 7; control), GII ( n = 7; thermal stress), GIII ( n = 7; nutritional stress) and GIV ( n = 7; combined stress). The animals were stall fed with a diet consisting of 60% roughage and 40% concentrate. GI and GII ewes were provided with ad libitum feeding while GIII and GIV ewes were provided with restricted feed (30% intake of GI ewes) to induce nutritional stress. GII and GIV ewes were kept in climatic chamber at 40°C and 55% RH for 6 h a day between 1000 hours and 1600 hours to induce thermal stress. The study was conducted for a period of two estrus cycles. The parameters studied were Hb, PCV, glucose, total protein, total cholesterol, ACP, ALP, cortisol, T4, T3, and insulin. Combined stress significantly ( P ewes. It can be concluded from this study that two stressors occurring simultaneously may impact severely on the biological functions necessary to maintain homeostasis in sheep.

  8. Stress relaxation of thermally bowed fuel pins

    International Nuclear Information System (INIS)

    Crossland, I.G.; Speight, M.V.

    1983-01-01

    The presence of cross-pin temperature gradients in nuclear reactor fuel pins produces differential thermal expansion which, in turn, causes the fuel pin to bow elastically. If the pin is restrained in any way, such thermal bowing causes the pin to be stressed. At high temperatures these stresses can relax by creep and it is shown here that this causes the pin to suffer an additional permanent deflection, so that when the cross-pin temperature difference is removed the pin remains bowed. By representing the cylindrical pin by an equivalent I-beam, the present work examines this effect when it takes place by secondary creep. Two restraint systems are considered, and it is demonstrated that the rate of relaxation depends mainly upon the creep equation, and hence the temperature, and also the magnitude of the initial stresses. (author)

  9. Thermal stresses investigation of a gas turbine blade

    Science.gov (United States)

    Gowreesh, S.; Pravin, V. K.; Rajagopal, K.; Veena, P. H.

    2012-06-01

    The analysis of structural and thermal stress values that are produced while the turbine is operating are the key factors of study while designing the next generation gas turbines. The present study examines structural, thermal, modal analysis of the first stage rotor blade of a two stage gas turbine. The design features of the turbine segment of the gas turbine have been taken from the preliminary design of a power turbine for maximization of an existing turbojet engine with optimized dump gap of the combustion chamber, since the allowable temperature on the turbine blade dependents on the hot gas temperatures from the combustion chamber. In the present paper simplified 3-D Finite Element models are developed with governing boundary conditions and solved using the commercial FEA software ANSYS. As the temperature has a significant effect on the overall stress on the rotor blades, a detail study on mechanical and thermal stresses are estimated and evaluated with the experimental values.

  10. Organizational Stress Moderates the Relationship between Mental Health Provider Adaptability and Organizational Commitment

    Science.gov (United States)

    Green, Amy E.; Dishop, Christopher; Aarons, Gregory A

    2016-01-01

    Objective Community mental health providers often operate within stressful work environments and are at high risk for emotional exhaustion, which can negatively affect job performance and client satisfaction with services. This cross-sectional study examines the relationships between organizational stress, provider adaptability, and organizational commitment. Methods Variables were analyzed using moderated multi-level regression in a sample of 311 mental health providers from 49 community mental health programs. Results Stressful organizational climate, characterized by high levels of emotional exhaustion, role conflict, and role overload, was negatively related to organizational commitment. Organizational stress moderated the relationship between provider adaptability and organizational commitment, such that those who were more adaptable had greater levels of organizational commitment when organizational stress was low, but were less committed than those who were less adaptable when organizational stress was high. Conclusions In the current study, providers higher in adaptability may perceive their organization as a greater fit when characterized by lower levels of stressfulness; however, highly adaptable providers may also exercise choice that manifests in lower commitment to staying in an overly stressful work environment. Service systems and organizational contexts are becoming increasingly demanding and stressful for direct mental health service providers. Therefore, community mental health organizations should assess and understand their organizational climate and intervene with empirically based organizational strategies when necessary to reduce stressful climates and maintain desirable employees. PMID:27301760

  11. Diminished stress resistance and defective adaptive homeostasis in age-related diseases.

    Science.gov (United States)

    Lomeli, Naomi; Bota, Daniela A; Davies, Kelvin J A

    2017-11-01

    Adaptive homeostasis is defined as the transient expansion or contraction of the homeostatic range following exposure to subtoxic, non-damaging, signaling molecules or events, or the removal or cessation of such molecules or events ( Mol. Aspects Med. (2016) 49, 1-7 ). Adaptive homeostasis allows us to transiently adapt (and then de-adapt) to fluctuating levels of internal and external stressors. The ability to cope with transient changes in internal and external environmental stress, however, diminishes with age. Declining adaptive homeostasis may make older people more susceptible to many diseases. Chronic oxidative stress and defective protein homeostasis (proteostasis) are two major factors associated with the etiology of age-related disorders. In the present paper, we review the contribution of impaired responses to oxidative stress and defective adaptive homeostasis in the development of age-associated diseases. © 2017 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society.

  12. Functional analysis of atfA gene to stress response in pathogenic thermal dimorphic fungus Penicillium marneffei.

    Directory of Open Access Journals (Sweden)

    Panjaphorn Nimmanee

    Full Text Available Penicillium marneffei, the pathogenic thermal dimorphic fungus is a causative agent of a fatal systemic disease, penicilliosis marneffei, in immunocompromised patients especially HIV patients. For growth and survival, this fungus has to adapt to environmental stresses outside and inside host cells and this adaptation requires stress signaling pathways and regulation of gene expression under various kinds of stresses. In this report, P. marneffei activating transcription factor (atfA gene encoding bZip-type transcription factor was characterized. To determine functions of this gene, atfA isogenic mutant strain was constructed using the modified split marker recombination method. The phenotypes and susceptibility to varieties of stresses including osmotic, oxidative, heat, UV, cell wall and cell membrane stresses of the mutant strain were compared with the wild type and the atfA complemented strains. Results demonstrated that the mRNA expression level of P. marneffei atfA gene increased under heat stress at 42°C. The atfA mutant was more sensitive to sodium dodecyl sulphate, amphotericin B and tert-butyl hydroperoxide than the wild type and complemented strains but not hydrogen peroxide, menadione, NaCl, sorbitol, calcofluor white, itraconazole, UV stresses and heat stress at 39°C. In addition, recovery of atfA mutant conidia after mouse and human macrophage infections was significantly decreased compared to those of wild type and complemented strains. These results indicated that the atfA gene was required by P. marneffei under specific stress conditions and might be necessary for fighting against host immune cells during the initiation of infection.

  13. Predicted thermal and stress environments in the vicinity of repository openings

    International Nuclear Information System (INIS)

    Bauer, S.J.; Hardy, M.P.; Lin, M.

    1991-01-01

    An understanding of the thermal and stress environment in the vicinity of repository openings is important for preclosure performance considerations and worker health and safety considerations for the proposed high-level radioactive waste repository at Yucca Mountain. This paper presents the results of two and three dimensional numerical analyses which have determined the thermal and stress environments for typical repository openings. In general, it is predicted that openings close to heat sources attain high temperatures and experience a significant stress increase. Openings away from heat sources experience more uniform temperature changes and experience a stress change which results in part from a far-field thermal loading

  14. Geographic variation in responses of European yellow dung flies to thermal stress.

    Science.gov (United States)

    Bauerfeind, Stephanie S; Sørensen, Jesper G; Loeschcke, Volker; Berger, David; Broder, E Dale; Geiger, Madeleine; Ferrari, Manuela; Blanckenhorn, Wolf U

    2018-04-01

    Climatic conditions can be very heterogeneous even over small geographic scales, and are believed to be major determinants of the abundance and distribution of species and populations. Organisms are expected to evolve in response to the frequency and magnitude of local thermal extremes, resulting in local adaptation. Using replicate yellow dung fly (Scathophaga stercoraria; Diptera: Scathophagidae) populations from cold (northern Europe) and warm climates (southern Europe), we compared 1) responses to short-term heat and cold shocks in both sexes, 2) heat shock protein (Hsp70) expression in adults and eggs, and 3) female reproductive traits when facing short-term heat stress during egg maturation. Contrary to expectations, thermal traits showed minor geographic differentiation, with weak evidence for greater heat resistance of southern flies but no differentiation in cold resistance. Hsp70 protein expression was little affected by heat stress, indicating systemic rather than induced regulation of the heat stress response, possibly related to this fly group's preference for cold climes. In contrast, sex differences were pronounced: males (which are larger) endured hot temperatures longer, while females featured higher Hsp70 expression. Heat stress negatively affected various female reproductive traits, reducing first clutch size, overall reproductive investment, egg lipid content, and subsequent larval hatching. These responses varied little across latitude but somewhat among populations in terms of egg size, protein content, and larval hatching success. Several reproductive parameters, but not Hsp70 expression, exhibited heritable variation among full-sib families. Rather than large-scale clinal geographic variation, our study suggests some local geographic population differentiation in the ability of yellow dung flies to buffer the impact of heat stress on reproductive performance. Copyright © 2018 Elsevier Ltd. All rights reserved.

  15. Three-dimensional modelling of thermal stress in floating zone silicon crystal growth

    Science.gov (United States)

    Plate, Matiss; Krauze, Armands; Virbulis, Jānis

    2018-05-01

    During the growth of large diameter silicon single crystals with the industrial floating zone method, undesirable level of thermal stress in the crystal is easily reached due to the inhomogeneous expansion as the crystal cools down. Shapes of the phase boundaries, temperature field and elastic material properties determine the thermal stress distribution in the solid mono crystalline silicon during cylindrical growth. Excessive stress can lead to fracture, generation of dislocations and altered distribution of intrinsic point defects. Although appearance of ridges on the crystal surface is the decisive factor of a dislocation-free growth, the influence of these ridges on the stress field is not completely clear. Here we present the results of thermal stress analysis for 4” and 5” diameter crystals using a quasi-stationary three dimensional mathematical model including the material anisotropy and the presence of experimentally observed ridges which cannot be addressed with axis-symmetric models. The ridge has a local but relatively strong influence on thermal stress therefore its relation to the origin of fracture is hypothesized. In addition, thermal stresses at the crystal rim are found to increase for a particular position of the crystal radiation reflector.

  16. Evolving local climate adaptation strategies: incorporating influences of socio–economic stress

    OpenAIRE

    Hjerpe, Mattias; Glaas, Erik

    2012-01-01

    Socio-economic and climatic stresses affect local communities’ vulnerability toflooding. Better incorporation of socio-economic stress in local vulnerability assessments isimportant when planning for climate adaptation. This is rarely done due to insufficientunderstanding of their interaction, in both theory and practice. The omission leads to criticalweaknesses in local adaptation strategies. This study analyses how socio-economic stressinteract with climatic stress and shape local vulnerabi...

  17. Multi-omics analysis of thermal stress response in a zooxanthellate cnidarian reveals the importance of associating with thermotolerant symbionts

    KAUST Repository

    Cziesielski, Maha J.

    2018-04-18

    Corals and their endosymbiotic dinoflagellates of the genus Symbiodinium have a fragile relationship that breaks down under heat stress, an event known as bleaching. However, many coral species have adapted to high temperature environments such as the Red Sea (RS). To investigate mechanisms underlying temperature adaptation in zooxanthellate cnidarians we compared transcriptome- and proteome-wide heat stress response (24 h at 32°C) of three strains of the model organism Aiptasia pallida from regions with differing temperature profiles; North Carolina (CC7), Hawaii (H2) and the RS. Correlations between transcript and protein levels were generally low but inter-strain comparisons highlighted a common core cnidarian response to heat stress, including protein folding and oxidative stress pathways. RS anemones showed the strongest increase in antioxidant gene expression and exhibited significantly lower reactive oxygen species (ROS) levels in hospite However, comparisons of antioxidant gene and protein expression between strains did not show strong differences, indicating similar antioxidant capacity across the strains. Subsequent analysis of ROS production in isolated symbionts confirmed that the observed differences of ROS levels in hospite were symbiont-driven. Our findings indicate that RS anemones do not show increased antioxidant capacity but may have adapted to higher temperatures through association with more thermally tolerant symbionts.

  18. Multi-omics analysis of thermal stress response in a zooxanthellate cnidarian reveals the importance of associating with thermotolerant symbionts

    KAUST Repository

    Cziesielski, Maha J.; Liew, Yi Jin; Cui, Guoxin; Schmidt-Roach, Sebastian; Campana, Sara; Marondedze, Claudius; Aranda, Manuel

    2018-01-01

    Corals and their endosymbiotic dinoflagellates of the genus Symbiodinium have a fragile relationship that breaks down under heat stress, an event known as bleaching. However, many coral species have adapted to high temperature environments such as the Red Sea (RS). To investigate mechanisms underlying temperature adaptation in zooxanthellate cnidarians we compared transcriptome- and proteome-wide heat stress response (24 h at 32°C) of three strains of the model organism Aiptasia pallida from regions with differing temperature profiles; North Carolina (CC7), Hawaii (H2) and the RS. Correlations between transcript and protein levels were generally low but inter-strain comparisons highlighted a common core cnidarian response to heat stress, including protein folding and oxidative stress pathways. RS anemones showed the strongest increase in antioxidant gene expression and exhibited significantly lower reactive oxygen species (ROS) levels in hospite However, comparisons of antioxidant gene and protein expression between strains did not show strong differences, indicating similar antioxidant capacity across the strains. Subsequent analysis of ROS production in isolated symbionts confirmed that the observed differences of ROS levels in hospite were symbiont-driven. Our findings indicate that RS anemones do not show increased antioxidant capacity but may have adapted to higher temperatures through association with more thermally tolerant symbionts.

  19. Organizational Stress as Moderator of Relationship Between Mental Health Provider Adaptability and Organizational Commitment.

    Science.gov (United States)

    Green, Amy E; Dishop, Christopher R; Aarons, Gregory A

    2016-10-01

    Community mental health providers often operate within stressful work environments and are at high risk of emotional exhaustion, which can negatively affect job performance and client satisfaction with services. This cross-sectional study examined the relationships between organizational stress, provider adaptability, and organizational commitment. Variables were analyzed with moderated multilevel regression in a sample of 311 mental health providers from 49 community mental health programs. Stressful organizational climate, characterized by high levels of emotional exhaustion, role conflict, and role overload, was negatively related to organizational commitment. Organizational stress moderated the relationship between provider adaptability and organizational commitment, such that those who were more adaptable had greater levels of organizational commitment when organizational stress was low but were less committed than those who were less adaptable when organizational stress was high. Providers higher in adaptability may perceive their organization as a greater fit when the work environment is less stressful; however, highly adaptable providers may also exercise choice that manifests in lower commitment to staying in an overly stressful work environment. Service systems and organizational contexts are becoming increasingly demanding and stressful for direct mental health service providers. Therefore, community mental health organizations should assess and understand their organizational climate and intervene with empirically based organizational strategies when necessary to reduce stressful climates and maintain adaptable employees.

  20. Thermal Stress Behavior of Micro- and Nano-Size Aluminum Films

    International Nuclear Information System (INIS)

    Hanabusa, T.; Kusaka, K.; Nishida, M.

    2008-01-01

    In-situ observation of thermal stresses in thin films deposited on silicon substrate was made by X-ray and synchrotron radiation. Specimens prepared in this experiment were micro- and nano-size thin aluminum films with and without passivation film. The thickness of the film was 1 micrometer for micro-size films and 10, 20 and 50 nanometer for nano-size films. The stress measurement in micro-size films was made by X-ray radiation whereas the measurement of nano-size films was made by synchrotron radiation. Residual stress measurement revealed tensile stresses in all as-deposited films. Thermal stresses were measured in a series of heating- and cooling-stage. Thermal stress behavior of micro-size films revealed hysteresis loop during a heating and cooling process. The width of a hysteresis loop was larger in passivated film that unpassivated film. No hysteresis loops were observed in nano-size films with SiO 2 passivation. Strengthning mechanism in thin films was discussed on a passivation film and a film thickness

  1. Thermotolerant Yeast Strains Adapted by Laboratory Evolution Show Trade-Off at Ancestral Temperatures and Preadaptation to Other Stresses

    DEFF Research Database (Denmark)

    Caspeta, Luis; Nielsen, Jens

    2015-01-01

    adaptive laboratory evolution, we previously isolated seven Saccharomyces cerevisiae strains with improved growth at 40°C. Here, we show that genetic adaptations to high temperature caused a growth trade-off at ancestral temperatures, reduced cellular functions, and improved tolerance of other stresses...... in the ancestral strain. The latter is an advantageous attribute for acquiring thermotolerance and correlates with the reduction of yeast functions associated with loss of respiration capacity. This trait caused glycerol overproduction that was associated with the growth trade-off at ancestral temperatures....... In combination with altered sterol composition of cellular membranes, glycerol overproduction was also associated with yeast osmotolerance and improved tolerance of high concentrations of glucose and ethanol. Our study shows that thermal adaptation of yeast is suitable for improving yeast resistance...

  2. Effect of Thermal Stresses on the Failure Criteria of Fiber Composites

    DEFF Research Database (Denmark)

    Leong, Martin Klitgaard; Sankar, Bhavani V.

    2010-01-01

    , the latter, called micro-thermal stresses, has not been given much attention. In this paper the Direct Micromechanics Method is used to investigate the effects of micro-thermal stresses on the failure envelope of composites. Using FEA the unit-cell of the composite is analyzed. Assuming the failure criteria...... for the fiber and matrix are known, the exact failure envelope is developed. Using the micromechanics results, the Tsai-Wu failure envelope is modified to account for the micro-thermal stresses. The approach is demonstrated using two example structures at cryogenic temperature....

  3. Thermotolerant Yeast Strains Adapted by Laboratory Evolution Show Trade-Off at Ancestral Temperatures and Preadaptation to Other Stresses.

    Science.gov (United States)

    Caspeta, Luis; Nielsen, Jens

    2015-07-21

    A major challenge for the production of ethanol from biomass-derived feedstocks is to develop yeasts that can sustain growth under the variety of inhibitory conditions present in the production process, e.g., high osmolality, high ethanol titers, and/or elevated temperatures (≥ 40 °C). Using adaptive laboratory evolution, we previously isolated seven Saccharomyces cerevisiae strains with improved growth at 40 °C. Here, we show that genetic adaptations to high temperature caused a growth trade-off at ancestral temperatures, reduced cellular functions, and improved tolerance of other stresses. Thermotolerant yeast strains showed horizontal displacement of their thermal reaction norms to higher temperatures. Hence, their optimal and maximum growth temperatures increased by about 3 °C, whereas they showed a growth trade-off at temperatures below 34 °C. Computational analysis of the physical properties of proteins showed that the lethal temperature for yeast is around 49 °C, as a large fraction of the yeast proteins denature above this temperature. Our analysis also indicated that the number of functions involved in controlling the growth rate decreased in the thermotolerant strains compared with the number in the ancestral strain. The latter is an advantageous attribute for acquiring thermotolerance and correlates with the reduction of yeast functions associated with loss of respiration capacity. This trait caused glycerol overproduction that was associated with the growth trade-off at ancestral temperatures. In combination with altered sterol composition of cellular membranes, glycerol overproduction was also associated with yeast osmotolerance and improved tolerance of high concentrations of glucose and ethanol. Our study shows that thermal adaptation of yeast is suitable for improving yeast resistance to inhibitory conditions found in industrial ethanol production processes. Yeast thermotolerance can significantly reduce the production costs of biomass

  4. Metabolic heat production and thermal conductance are mass-independent adaptations to thermal environment in birds and mammals.

    Science.gov (United States)

    Fristoe, Trevor S; Burger, Joseph R; Balk, Meghan A; Khaliq, Imran; Hof, Christian; Brown, James H

    2015-12-29

    The extent to which different kinds of organisms have adapted to environmental temperature regimes is central to understanding how they respond to climate change. The Scholander-Irving (S-I) model of heat transfer lays the foundation for explaining how endothermic birds and mammals maintain their high, relatively constant body temperatures in the face of wide variation in environmental temperature. The S-I model shows how body temperature is regulated by balancing the rates of heat production and heat loss. Both rates scale with body size, suggesting that larger animals should be better adapted to cold environments than smaller animals, and vice versa. However, the global distributions of ∼9,000 species of terrestrial birds and mammals show that the entire range of body sizes occurs in nearly all climatic regimes. Using physiological and environmental temperature data for 211 bird and 178 mammal species, we test for mass-independent adaptive changes in two key parameters of the S-I model: basal metabolic rate (BMR) and thermal conductance. We derive an axis of thermal adaptation that is independent of body size, extends the S-I model, and highlights interactions among physiological and morphological traits that allow endotherms to persist in a wide range of temperatures. Our macrophysiological and macroecological analyses support our predictions that shifts in BMR and thermal conductance confer important adaptations to environmental temperature in both birds and mammals.

  5. Adaptive implicit method for thermal compositional reservoir simulation

    Energy Technology Data Exchange (ETDEWEB)

    Agarwal, A.; Tchelepi, H.A. [Society of Petroleum Engineers, Richardson, TX (United States)]|[Stanford Univ., Palo Alto (United States)

    2008-10-15

    As the global demand for oil increases, thermal enhanced oil recovery techniques are becoming increasingly important. Numerical reservoir simulation of thermal methods such as steam assisted gravity drainage (SAGD) is complex and requires a solution of nonlinear mass and energy conservation equations on a fine reservoir grid. The most currently used technique for solving these equations is the fully IMplicit (FIM) method which is unconditionally stable, allowing for large timesteps in simulation. However, it is computationally expensive. On the other hand, the method known as IMplicit pressure explicit saturations, temperature and compositions (IMPEST) is computationally inexpensive, but it is only conditionally stable and restricts the timestep size. To improve the balance between the timestep size and computational cost, the thermal adaptive IMplicit (TAIM) method uses stability criteria and a switching algorithm, where some simulation variables such as pressure, saturations, temperature, compositions are treated implicitly while others are treated with explicit schemes. This presentation described ongoing research on TAIM with particular reference to thermal displacement processes such as the stability criteria that dictate the maximum allowed timestep size for simulation based on the von Neumann linear stability analysis method; the switching algorithm that adapts labeling of reservoir variables as implicit or explicit as a function of space and time; and, complex physical behaviors such as heat and fluid convection, thermal conduction and compressibility. Key numerical results obtained by enhancing Stanford's General Purpose Research Simulator (GPRS) were also presented along with a list of research challenges. 14 refs., 2 tabs., 11 figs., 1 appendix.

  6. Thermal Super-Pixels for Bimodal Stress Recognition

    DEFF Research Database (Denmark)

    Irani, Ramin; Nasrollahi, Kamal; Dhall, Abhinav

    2016-01-01

    to be in touch with the body which is not always practical. Contact-free monitoring of the stress by a camera [1, 2] can be an alternative. These systems usually utilize only an RGB or a thermal camera to recognize stress. To the best of our knowledge, the only work on fusion of these two modalities for stress......Stress is a response to time pressure or negative environmental conditions. If its stimulus iterates or stays for a long time, it affects health conditions. Thus, stress recognition is an important issue. Traditional systems for this purpose are mostly contact-based, i.e., they require a sensor...

  7. Concrete creep and thermal stresses:new creep models and their effects on stress development

    OpenAIRE

    Westman, Gustaf

    1999-01-01

    This thesis deals with the problem of creep in concrete and its influence on thermal stress development. New test frames were developed for creep of high performance concrete and for measurements of thermal stress development. Tests were performed on both normal strength and high performance concretes. Two new models for concrete creep are proposed. Firstly, a viscoelastic model, the triple power law, is supplemented with two additional functions for an improved modelling of the early age cre...

  8. Genetic differences in thermal tolerance of eastern mosquitofish (Gambusia holbrooki; Poeciliidae) from ambient and thermal ponds

    Energy Technology Data Exchange (ETDEWEB)

    Meffe, G.K.; Weeks, S.C.; Mulvey, M.; Kandl, K.L. [Georgia Univ., Aiken, SC (United States)

    1995-12-01

    Thermal tolerance and genetic variation in populations of the eastern mosquitofish exposed to different thermal environments were examined. One population was exposed to high, semilethal temperatures for 60-90 mosquito fish generations (30 years), while the other existed in an unheated pond. Critical thermal maximum of each population was determined. Results indicated that mosquitofish have the genetic variation necessary to adapt to local temperature increases over a long time. Even the population exposed to semilethal temperatures for 30 years adapted to the acute stress. Therefore, the currently postulated gradual rise in global temperatures would not pose a serious challenge to this species. It was suspected that adaptations to higher thermal regimes was, at least in part, the result of selection on genetic variation for temperature tolerance within populations. 26 refs., 3 tabs., 3 figs.

  9. Stress and Displacement Analysis of Microreactors during Thermal and Vacuum Loading

    Science.gov (United States)

    2017-09-07

    ARL-TR-8121 ● SEP 2017 US Army Research Laboratory Stress and Displacement Analysis of Microreactors during Thermal and Vacuum...is no longer needed. Do not return it to the originator. ARL-TR-8121 ● SEP 2017 US Army Research Laboratory Stress and...TITLE AND SUBTITLE Stress and Displacement Analysis of Microreactors during Thermal and Vacuum Loading 5a. CONTRACT NUMBER 5b. GRANT NUMBER

  10. Plasma. beta. -endorphin and stress hormone levels during adaptation and stress

    Energy Technology Data Exchange (ETDEWEB)

    Lishmanov, Yu.B.; Trifonova, Zh.V.; Tsibin, A.N.; Maslova, L.V.; Dement' eva, L.A.

    1987-09-01

    This paper describes a comparative study of ..beta..-endorphin and stress hormone levels in the blood plasma of rats during stress and adaptation. Immunoreactive ..beta..-endorphin in the blood plasma was assayed by means of a kit after preliminary isolation of the ..beta..-endorphin fraction by affinity chromatography on sepharose; ACTH was assayed with a kit and cortisol, insulin, thyroxine and tri-iodothyronine by means of kits from Izotop. Determination of plasma levels of ..beta..-endorphin and other opioids could evidently be an important method of assessing the state of resistance of the organism to stress.

  11. Dynamic thermal environment and thermal comfort.

    Science.gov (United States)

    Zhu, Y; Ouyang, Q; Cao, B; Zhou, X; Yu, J

    2016-02-01

    Research has shown that a stable thermal environment with tight temperature control cannot bring occupants more thermal comfort. Instead, such an environment will incur higher energy costs and produce greater CO2 emissions. Furthermore, this may lead to the degeneration of occupants' inherent ability to combat thermal stress, thereby weakening thermal adaptability. Measured data from many field investigations have shown that the human body has a higher acceptance to the thermal environment in free-running buildings than to that in air-conditioned buildings with similar average parameters. In naturally ventilated environments, occupants have reported superior thermal comfort votes and much greater thermal comfort temperature ranges compared to air-conditioned environments. This phenomenon is an integral part of the adaptive thermal comfort model. In addition, climate chamber experiments have proven that people prefer natural wind to mechanical wind in warm conditions; in other words, dynamic airflow can provide a superior cooling effect. However, these findings also indicate that significant questions related to thermal comfort remain unanswered. For example, what is the cause of these phenomena? How we can build a comfortable and healthy indoor environment for human beings? This article summarizes a series of research achievements in recent decades, tries to address some of these unanswered questions, and attempts to summarize certain problems for future research. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  12. Thermal stresses in an orthotropic rectangular plate with a rigid ribbonlike inclusion

    International Nuclear Information System (INIS)

    Sumi, N.

    1981-01-01

    On the basis of the complex variable method for determining the stationary two-dimensional thermal stresses, the thermal stresses in an orthotropic rectangular plate with a rigid ribbonlike inclusion under a steady state temperature field is considered. The solution is found by the analytic continuation argument and the modified mapping-collocation technique. Numerical results indicate a dependence of the orthotropic stress intensity factors on the thermal, elastic and geometrical constants over a certain parameter range. (orig.)

  13. Stress hysteresis during thermal cycling of plasma-enhanced chemical vapor deposited silicon oxide films

    Science.gov (United States)

    Thurn, Jeremy; Cook, Robert F.

    2002-02-01

    The mechanical response of plasma-enhanced chemical vapor deposited SiO2 to thermal cycling is examined by substrate curvature measurement and depth-sensing indentation. Film properties of deposition stress and stress hysteresis that accompanied thermal cycling are elucidated, as well as modulus, hardness, and coefficient of thermal expansion. Thermal cycling is shown to result in major plastic deformation of the film and a switch from a compressive to a tensile state of stress; both athermal and thermal components of the net stress alter in different ways during cycling. A mechanism of hydrogen incorporation and release from as-deposited silanol groups is proposed that accounts for the change in film properties and state of stress.

  14. Morphological substantiation for acute immobilization stress-related disorders of adaptation mechanisms.

    Science.gov (United States)

    Koptev, Mykhailo M; Vynnyk, Nataliia I

    Nowadays, an individual is being constantly accompanied by stresses in his/her everyday life. Stress reactions, produced in the process of evolution, have become the organisms' response to emergency action or pathological factors and are the important link in adaptation process. However, the adverse course of stress reaction can lead to derangement of the adaptation mechanisms in the body and become the element of the pathogenesis of various diseases. The study was aimed at morphological substantiation of derangement of adaptation mechanisms in white Wistar rats caused by the acute immobilization stress. 40 Wistar white male rats of 240-260 g body weight aged 8-10 months were involved into study. 20 laboratory animals were assigned to the main group and the rest 20 rats formed the control (II) group. Experimental stress model was simulated by immobilization of rats, lying supine, for 6 hours. Morphological examination of heart, lungs and kidneys was carried out after animals' decapitation, which proved the derangement of rats' adaptation mechanisms caused by the acute immobilization stress. It has been established that six-hour immobility of rats, lying in the supine position, led to the development of destructive phenomena, hemorrhagic lesions and impaired hemomicrocirculation. Microscopically, the acute immobilization stress causes significant subendocardial hemorrhages, plethora of vessels of hemomicrocirculatory flow with dysdiemorrhysis, myocardial intersticium edema in the heart. Histologically, immobilization-induced trauma causes significant hemodynamic disorders, spasm of arterioles and considerable venous hyperemia, concomitant with microthrombosis in kidneys; at the same time dystrophic lesions and desquamation of epithelium of renal tubules has been observed in renal corpuscles. The abovementioned structural changes can contribute to origination and development of multiple lesions, demonstrating the morphologically grounded role of the acute

  15. Thermal stress analysis of gravity support system for ITER based on ANSYS

    International Nuclear Information System (INIS)

    Liang Shangming; Yan Xijiang; Huang Yufeng; Wang Xianzhou; Hou Binglin; Li Pengyuan; Jian Guangde; Liu Dequan; Zhou Caipin

    2009-01-01

    A method for building the finite element model of the gravity support system for International Thermonuclear Experimental Reactor (ITER) was proposed according to the characteristics of the gravity support system with the cyclic symmetry. A mesh dividing method, which has high precision and an acceptable calculating scale, was used, and a three dimensional finite element model for the toroidal 20 degree sector of the gravity support system was built by using ANSYS. Meantime, the steady-state thermal analysis and thermal-structural coupling analysis of the gravity support system were performed. The thermal stress distributions and the maximal thermal stress values of all parts of the gravity support system were obtained, and the stress intensity of parts of the gravity support system was analyzed. The results of thermal stress analysis lay the solid foundation for design and improvement for gravity supports system for ITER. (authors)

  16. Development of thermal stress screening method. Application of green function method

    International Nuclear Information System (INIS)

    Furuhashi, Ichiro; Shibamoto, Hiroshi; Kasahara, Naoto

    2004-01-01

    This work was achieved for the development of the screening method of thermal transient stresses in FBR components. We proposed an approximation method for evaluations of thermal stress under variable heat transfer coefficients (non-linear problems) using the Green functions of thermal stresses with constant heat transfer coefficients (linear problems). Detailed thermal stress analyses provided Green functions for a skirt structure and a tube-sheet of Intermediate Heat Exchanger. The upper bound Green functions were obtained by the analyses using those upper bound heat transfer coefficients. The medium and the lower bound Green functions were got by the analyses of those under medium and the lower bound heat transfer coefficients. Conventional evaluations utilized the upper bound Green functions. On the other hand, we proposed a new evaluation method by using the upper bound, medium and the lower bound Green functions. The comparison of above results gave the results as follows. The conventional evaluations were conservative and appropriate for the cases under one fluid thermal transient structure such as the skirt. The conventional evaluations were generally conservative for the complicated structures under two or more fluids thermal transients such as the tube-sheet. But the danger locations could exists for the complicated structures under two or more fluids transients, namely the conventional evaluations were non-conservative. The proposed evaluations gave good estimations for these complicated structures. Though above results, we have made the basic documents of the screening method of thermal transient stresses using the conventional method and the new method. (author)

  17. Stress assessment in piping under synthetic thermal loads emulating turbulent fluid mixing

    Energy Technology Data Exchange (ETDEWEB)

    Costa Garrido, Oriol, E-mail: oriol.costa@ijs.si; El Shawish, Samir, E-mail: samir.elshawish@ijs.si; Cizelj, Leon, E-mail: leon.cizelj@ijs.si

    2015-03-15

    Highlights: • Generation of complex space-continuous and time-dependent temperature fields. • 1D and 3D thermo-mechanical analyses of pipes under complex surface thermal loads. • Surface temperatures and stress fluctuations are highly linearly correlated. • 1D and 3D results agree for a wide range of Fourier and Biot numbers. • Global thermo-mechanical loading promotes non-equibiaxial stress state. - Abstract: Thermal fatigue assessment of pipes due to turbulent fluid mixing in T-junctions is a rather difficult task because of the existing uncertainties and variability of induced thermal stresses. In these cases, thermal stresses arise on three-dimensional pipe structures due to complex thermal loads, known as thermal striping, acting at the fluid-wall interface. A recently developed approach for the generation of space-continuous and time-dependent temperature fields has been employed in this paper to reproduce fluid temperature fields of a case study from the literature. The paper aims to deliver a detailed study of the three-dimensional structural response of piping under the complex thermal loads arising in fluid mixing in T-junctions. Results of three-dimensional thermo-mechanical analyses show that fluctuations of surface temperatures and stresses are highly linearly correlated. Also, surface stress fluctuations, in axial and hoop directions, are almost equi-biaxial. These findings, representative on cross sections away from system boundaries, are moreover supported by the sensitivity analysis of Fourier and Biot numbers and by the comparison with standard one-dimensional analyses. Agreement between one- and three-dimensional results is found for a wide range of studied parameters. The study also comprises the effects of global thermo-mechanical loading on the surface stress state. Implemented mechanical boundary conditions develop more realistic overall system deformation and promote non-equibiaxial stresses.

  18. Thermal stress analysis for fatigue damage evaluation at a mixing tee

    International Nuclear Information System (INIS)

    Kamaya, Masayuki; Nakamura, Akira

    2011-01-01

    Highlights: → Thermal stress and fatigue damage have been analyzed for a mixing tee. → Fatigue damage was accumulated near boundaries of the cold spot. → It was found that fatigue damage was brought about by fluctuation of cold spot. → Simple one-dimensional analysis could derive stress for fatigue evaluation. - Abstract: Fatigue cracks have been found at mixing tees where fluids of different temperature flow in. In this study, the thermal stress at a mixing tee was calculated by the finite element method using temperature transients obtained by a fluid dynamics simulation. The simulation target was an experiment for a mixing tee, in which cold water flowed into the main pipe from a branch pipe. The cold water flowed along the main pipe wall and caused a cold spot, at which the membrane stress was relatively large. Based on the evaluated thermal stress, the magnitude of the fatigue damage was assessed according to the linear damage accumulation rule and the rain-flow procedure. Precise distributions of the thermal stress and fatigue damage could be identified. Relatively large axial stress occurred downstream from the branch pipe due to the cold spot. The variation ranges of thermal stress and fatigue damage became large near the position 20 o from the symmetry line in the circumferential direction. The position of the cold spot changed slowly in the circumferential direction, and this was the main cause of the fatigue damage. The fatigue damage was investigated for various differences in the temperature between the main and branch pipes. Since the magnitude of accumulated damage increased abruptly when the temperature difference exceeded the value corresponding to the fatigue limit, it was suggested that the stress amplitude should be suppressed less than the fatigue limit. In the thermal stress analysis for fatigue damage assessment, it was found that the detailed three-dimensional structural analysis was not required. Namely, for the current case, a one

  19. Simplified calculation of thermal stresses - on the reduction of effort in the stress analysis of reactor components

    International Nuclear Information System (INIS)

    Karow, K.

    1984-01-01

    The fatigue behaviour of reactor components is predominantly determined from the in-service thermal stresses. The calculation of such stresses for a number of temperature transients in the adjacent fluid may be expensive, particularly with complicated structures. Under certain conditions this expense can be reduced considerably with the aid of a rule, which permits interpolation of thermal stresses from known reference values instead of calculation. This paper presents the derivation and method of application of this interpolation rule. The derivation procedure is based on well-known proportionalities between thermal stress range Δsigma in the structure and temperature change ΔT and rate of change T of the fluid in the extreme cases of an ideal thermal shock and quasi-steady-state conditions, respectively. For the real transients in between the relationship Δsigma proportional (ΔT)sup(x) Tsup(1-x)αsup(y) is proposed, where x is the shock-degree and lies between 0 and 1, and, additionally, y designates the influence of the heat transfer coefficient α. This formula yields the interpolation rule. The rule permits interpolation of stress ranges for additional thermal transients from at least 3 reference stresses via x and y. The procedure is applicable to any metallic structure, reduces fatigue analysis effort considerably and yields excellent results. The paper is split up into 2 parts. In the following the derivation of the rule is presented. The second part describes its application and will be published shortly. (orig.)

  20. Heat transfer and thermal stress analysis in fluid-structure coupled field

    International Nuclear Information System (INIS)

    Li, Ming-Jian; Pan, Jun-Hua; Ni, Ming-Jiu; Zhang, Nian-Mei

    2015-01-01

    In this work, three-dimensional simulation on conjugate heat transfer in a fluid-structure coupled field was carried out. The structure considered is from the dual-coolant lithium-lead (DCLL) blanket, which is the key technology of International Thermo-nuclear Experimental Reactor (ITER). The model was developed based on finite element-finite volume method and was employed to investigate mechanical behaviours of Flow Channel Insert (FCI) and heat transfer in the blanket under nuclear reaction. Temperature distribution, thermal deformation and thermal stresses were calculated in this work, and the effects of thermal conductivity, convection heat transfer coefficient and flow velocity were analyzed. Results show that temperature gradients and thermal stresses of FCI decrease when FCI has better heat conductivity. Higher convection heat transfer coefficient will result in lower temperature, thermal deformations and stresses in FCI. Analysis in this work could be a theoretical basis of blanket optimization. - Highlights: • We use FVM and FEM to investigate FCI structural safety considering heat transfer and FSI effects. • Higher convective heat transfer coefficient is beneficial for the FCI structural safety without much affect to bulk flow temperature. • Smaller FCI thermal conductivity can better prevent heat leakage into helium, yet will increase FCI temperature gradient and thermal stress. • Three-dimensional simulation on conjugate heat transfer in a fluid-structure coupled field was carried out

  1. Numerical Study on the Thermal Stress and its Formation Mechanism of a Thermoelectric Device

    Science.gov (United States)

    Pan, Tao; Gong, Tingrui; Yang, Wei; Wu, Yongjia

    2018-06-01

    The strong thermo-mechanical stress is one of the most critical failure mechanisms that affect the durability of thermoelectric devices. In this study, numerical simulations on the formation mechanism of the maximum thermal stress inside the thermoelectric device have been performed by using finite element method. The influences of the material properties and the thermal radiation on the thermal stress have been examined. The results indicate that the maximum thermal stress was located at the contact position between the two materials and occurred due to differential thermal expansions and displacement constraints of the materials. The difference in the calculated thermal stress value between the constant and the variable material properties was between 3% and 4%. At a heat flux of 1 W·cm-2 and an emissivity of 0.5, the influence of the radiation heat transfer on the thermal stress was only about 5%; however, when the heat flux was 20 W·cm-2 and the emissivity was 0.7, the influence of the radiation heat transfer was more than 30%.

  2. Dynamic characteristics of rotating pretwisted clamped-clamped beam under thermal stress

    International Nuclear Information System (INIS)

    Zhang, Bo; Li, Yueming; Lu, Wei Zhen

    2016-01-01

    Effects of thermal stress on the vibration characteristics, buckling limit and critical speed of a rotating pretwisted beam clamped to rigid hub at a stagger angle were investigated. By considering the work done by thermal stress, the thermal influence on stiffness matrix was introduced in the dynamic model. The motion equations were derived based on Lagrange equation by employing three pure Cartesian deformation variables combined with nonlinear von Karman strain formula. Numerical investigations studied the modal characteristics of the beam. Numerical results calculated from a commercial finite element code and obtained with the present modeling method were in good agreement with the previous results reported in the literature. The combined softening effects due to the thermal stress and the rotation motion were observed. Furthermore, it is shown that the inclusion of thermal stress is necessary for blades operating under a high temperature field. Buckling thermal loads and the critical rotating speed were calculated through solving the corresponding nonlinear equations numerically, and some pertinent conclusions are outlined. It is also found that the peak value position of the first mode shape approaches to the tip of blade with the increment of rotating speed and hub radius. However, the variation in the environment temperature causes only a slight alteration in the mode shape

  3. Dynamic characteristics of rotating pretwisted clamped-clamped beam under thermal stress

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Bo; Li, Yueming [State Key Laboratory for Strength and Vibration of Mechanical Structures, Shaanxi Key Laboratory of Environment and Control for Flight Vehicle, School of Aerospace, Xi' an Jiaotong UniversityXi' an (China); Lu, Wei Zhen [Dept. of Civil and Architectural Engineering, City University of Hong Kong, Hong Kong (China)

    2016-09-15

    Effects of thermal stress on the vibration characteristics, buckling limit and critical speed of a rotating pretwisted beam clamped to rigid hub at a stagger angle were investigated. By considering the work done by thermal stress, the thermal influence on stiffness matrix was introduced in the dynamic model. The motion equations were derived based on Lagrange equation by employing three pure Cartesian deformation variables combined with nonlinear von Karman strain formula. Numerical investigations studied the modal characteristics of the beam. Numerical results calculated from a commercial finite element code and obtained with the present modeling method were in good agreement with the previous results reported in the literature. The combined softening effects due to the thermal stress and the rotation motion were observed. Furthermore, it is shown that the inclusion of thermal stress is necessary for blades operating under a high temperature field. Buckling thermal loads and the critical rotating speed were calculated through solving the corresponding nonlinear equations numerically, and some pertinent conclusions are outlined. It is also found that the peak value position of the first mode shape approaches to the tip of blade with the increment of rotating speed and hub radius. However, the variation in the environment temperature causes only a slight alteration in the mode shape.

  4. Heat transfer and thermal stress analysis in grooved tubes

    Indian Academy of Sciences (India)

    ANSYS (1997) computer code has been used to analyse the thermal ... The numerical method is used succesfully to solve the governing equations ... thermal stress is an important criterion for consideration in the design of new compact heat.

  5. Stress in film/substrate system due to diffusion and thermal misfit effects

    International Nuclear Information System (INIS)

    Shao Shanshan; Xuan Fuzhen; Wang Zhengdong; Tu Shantung

    2009-01-01

    The stress in film/substrate systems has been analysed taking into consideration the coupling effects of diffusion and thermal misfit within the framework of Fick's second law. The solution of diffusion-induced stress in a film/substrate system involving the thermal misfit stress feedback is developed. The effects of modulus ratios, diffusivity ratios, thickness ratios of the substrate and the film and the partial molar volume of the diffusing component on the stress distribution in the film/substrate system are then discussed with the help of the finite difference method. Results indicate that the stresses in the film/substrate system vary with diffusion time. Diffusion enhances the magnitudes of film stress when the thermal misfit stress is compressive in the film. Furthermore, the absolute values of stress in the film increase with the increasing modulus ratios of the substrate and film, while they reduce with the increasing partial molar volume of the diffusing component and the diffusivity ratio of the substrate and the film.

  6. Effects of location, thermal stress and residual stress on corner cracks in nozzles with cladding

    International Nuclear Information System (INIS)

    McLean, J.L.; Cohen, L.M.; Besuner, P.M.

    1979-01-01

    The stress intensity factors (K 1 ) for corner cracks in a boiling water reactor feedwater nozzle with stainless steel cladding are obtained for loading by internal pressure and a fluid quench in the nozzle. Conditions both with and without residual stress in the component are considered. The residual stress is simulated by means of a reference temperature change. The stress distribution for the uncracked structure is obtained from a three-dimensional finite element model. A three-dimensional influence function (IF) method, in conjunction with the boundary-integral equation method for structural analysis, is employed to compute K 1 values from the uncracked stress distribution. For each type of loading K 1 values are given for cracks at 15 nozzle locations and for 6 crack depths. Reasonable agreement is noted between calculated and previously published pressure-induced K 1 values. Comparisons are made to determine the effect on K 1 of crack location, thermal stress and residual stress, as compared with pressure stress. For the thermal transient it is shown that K 1 for small crack depths is maximised early in the transient, while K 1 for large cracks is maximised later under steady state conditions. Computation should, therefore, be made for several transient time points and the maximum K 1 for a given crack depth should be used for design analysis. It is concluded that the effects on K 1 of location, thermal stresses and residual stresses are significant and generally too complex to evaluate without advanced numerical procedures. The utilised combination of finite element analysis of the uncracked structure and three-dimensional influence function analysis of the cracked structure is demonstrated and endorsed. (author)

  7. Prior stress exposure increases pain behaviors in a rat model of full thickness thermal injury.

    Science.gov (United States)

    Nyland, Jennifer E; McLean, Samuel A; Averitt, Dayna L

    2015-12-01

    Thermal burns among individuals working in highly stressful environments, such as firefighters and military Service Members, are common. Evidence suggests that pre-injury stress may exaggerate pain following thermal injury; however current animal models of burn have not evaluated the potential influence of pre-burn stress. This sham-controlled study evaluated the influence of prior stress exposure on post-burn thermal and mechanical sensitivity in male Sprague-Dawley rats. Rats were exposed to 20 min of inescapable swim stress or sham stress once per day for three days. Exposure to inescapable swim stress (1) increased the intensity and duration of thermal hyperalgesia after subsequent burn and (2) accelerated the onset of thermal hyperalgesia and mechanical allodynia after subsequent burn. This stress-induced exacerbation of pain sensitivity was reversed by pretreatment and concurrent treatment with the serotonin-norepinephrine reuptake inhibitor (SNRI) duloxetine. These data suggest a better understanding of mechanisms by which prior stress augments pain after thermal burn may lead to improved pain treatments for burn survivors. Copyright © 2015 Elsevier Ltd and ISBI. All rights reserved.

  8. Universal treatment of plumes and stresses for pressurized thermal shock evaluations

    International Nuclear Information System (INIS)

    Theofanous, T.G.; Angelini, S.; Yan, H.

    1991-01-01

    Thermally-induced stresses in a reactor pressure vessel wall, as a result of high-pressure safety injection, are an essential component of integrated risk analyses of pressurized thermal shock transients. Limiting cooldowns arise when this injection occurs under stagnated loop conditions which, in turn, correspond to a rather narrow range (in size) of small-break loss-of-coolant accidents. Moreover, at these conditions, the flow is thermally stratified, and in addition to the global cooldown, one must be concerned about the additional cooling potential due to the downcomer plumes formed by the cold streams pouring out of the cold legs. In the Nuclear Regulatory Commission's Integrated Pressurized Thermal Shock (IPTS) study, this stratification was calculated with the codes REMIX/NEWMIX. A comprehensive comparison with all available experimental data has currently been compiled. The stress analysis using this input was carried out at Oak Ridge National Laboratory using a one-dimensional approximation with the intent to conservatively bound the magnitude of thermal stresses

  9. Thermal stress relieving of dilute uranium alloys

    International Nuclear Information System (INIS)

    Eckelmeyer, K.H.

    1981-01-01

    The kinetics of thermal stress relieving of uranium - 2.3 wt % niobium, uranium - 2.0 wt % molybdenum, and uranium - 0.75 wt % titanium are reported and discussed. Two temperature regimes of stress relieving are observed. In the low temperature regime (T 0 C) the process appears to be controlled by an athermal microplasticity mechanism which can be completely suppressed by prior age hardening. In the high temperature regime (300 0 C 0 C) the process appears to be controlled by a classical diffusional creep mechanism which is strongly dependent on temperature and time. Stress relieving is accelerated in cases where it occurs simultaneously with age hardening. The potential danger of residual stress induced stress corrosion cracking of uranium alloys is discussed

  10. Thermal stress evaluation of the Viking RTG heat shield

    International Nuclear Information System (INIS)

    Stadter, J.T.; Weiss, R.O.

    1976-03-01

    Thermal stress analyses of the Viking RTG heat shield are presented. The primary purpose of the analyses was to determine the effects of the end cap and the finite length of the heat shield on the peak tensile stress in the barrel wall. The SAAS III computer code was used to calculate the thermal stresses; axisymmetric and plane section analyses were performed for a variety of temperature distributions. The study consisted of three parts. In the first phase, the influence of the end cap on the barrel wall stresses was examined by parametrically varying the modulus of elasticity of the contact zone between the end cap and the barrel. The second phase was concerned with stresses occurring as a result of an orbital decay reentry trajectory, and the effects of the magnitude and shape of the axial temperature gradient. The final part of the study was concerned with the circumferentially nonuniform temperature distribution which develops during a side-on stable reentry. The last part includes a comparison of stresses generated for a hexagonal cross section with those generated for a circular cross section

  11. Thermal Stress FE Analysis of Large-scale Gas Holder Under Sunshine Temperature Field

    Science.gov (United States)

    Li, Jingyu; Yang, Ranxia; Wang, Hehui

    2018-03-01

    The temperature field and thermal stress of Man type gas holder is simulated by using the theory of sunshine temperature field based on ASHRAE clear-sky model and the finite element method. The distribution of surface temperature and thermal stress of gas holder under the given sunshine condition is obtained. The results show that the thermal stress caused by sunshine can be identified as one of the important factors for the failure of local cracked oil leakage which happens on the sunny side before on the shady side. Therefore, it is of great importance to consider the sunshine thermal load in the stress analysis, design and operation of large-scale steel structures such as the gas holder.

  12. Effect of thermal stress on the performance of HgCdTe/Si diodes and FPAs

    International Nuclear Information System (INIS)

    Zhang, Shan; Hu, Xiao-Ning

    2012-01-01

    As a typical hetero-epitaxial material, the HgCdTe film which directly grows on the Si substrate possesses great residual stress for the large lattice and thermal expansion mismatch. Thermal stress caused by the thermal expansion mismatch dominates the stress mechanism after growth and seriously affects the device performance. In this paper, the performance of the HgCdTe/Si material, diodes and focal plane arrays under different thermal stress condition was studied. The experimental results indicate that the performance regularly changes with the thermal stress and all the results can be duplicated and recoverable. By analyzing the changes of the energy band under different stress conditions, it was found that the stress in the HgCdTe film impacts the film's characteristics. The HgCdTe film with tensile stress exhibits higher electron mobility, while with the compressive stress, the film exhibits higher hole mobility than that of the bulk HgCdTe crystal. Finally, the theoretical analysis can explain the experimental results well. (paper)

  13. Immune and stress responses in oysters with insights on adaptation.

    Science.gov (United States)

    Guo, Ximing; He, Yan; Zhang, Linlin; Lelong, Christophe; Jouaux, Aude

    2015-09-01

    Oysters are representative bivalve molluscs that are widely distributed in world oceans. As successful colonizers of estuaries and intertidal zones, oysters are remarkably resilient against harsh environmental conditions including wide fluctuations in temperature and salinity as well as prolonged air exposure. Oysters have no adaptive immunity but can thrive in microbe-rich estuaries as filter-feeders. These unique adaptations make oysters interesting models to study the evolution of host-defense systems. Recent advances in genomic studies including sequencing of the oyster genome have provided insights into oyster's immune and stress responses underlying their amazing resilience. Studies show that the oyster genomes are highly polymorphic and complex, which may be key to their resilience. The oyster genome has a large gene repertoire that is enriched for immune and stress response genes. Thousands of genes are involved in oyster's immune and stress responses, through complex interactions, with many gene families expanded showing high sequence, structural and functional diversity. The high diversity of immune receptors and effectors may provide oysters with enhanced specificity in immune recognition and response to cope with diverse pathogens in the absence of adaptive immunity. Some members of expanded immune gene families have diverged to function at different temperatures and salinities or assumed new roles in abiotic stress response. Most canonical innate immunity pathways are conserved in oysters and supported by a large number of diverse and often novel genes. The great diversity in immune and stress response genes exhibited by expanded gene families as well as high sequence and structural polymorphisms may be central to oyster's adaptation to highly stressful and widely changing environments. Copyright © 2015 Elsevier Ltd. All rights reserved.

  14. Thermal stress measurement in continuous welded rails using the hole-drilling method

    Science.gov (United States)

    Zhu, Xuan; Lanza di Scalea, Francesco; Fateh, Mahmood

    2016-04-01

    The absence of expansion joints in Continuous Welded Rail (CWR) has created the need for the railroad industry to determine the in-situ level of thermal stresses so as to prevent train accidents caused by rail buckling in hot weather and by rail breakage in cold weather. The development of non-destructive or semi-destructive methods for determining the level of thermal stresses in rails is today a high research priority. This study explores the known hole-drilling method as a possible solution to this problem. A new set of calibration coefficients to compute the relieved stress field with the finer hole depth increments was determined by a 3D Finite Element Analysis that modeled the entire hole geometry, including the mechanics of the hole bottom and walls. To compensate the residual stress components, a linear relationship was experimentally established between the longitudinal and the vertical residual stresses of two common sizes of rails, the 136RE and the 141RE, with statistical significance. This result was then utilized to isolate the longitudinal thermal stress component in hole-drilling tests conducted on the 136RE and 141RE thermally-loaded rails at the Large-scale CWR Test-bed of UCSD's Powell Research Laboratories. The results from the Test-bed showed that the hole-drilling procedure, with the appropriate residual stress compensation, can indeed estimate the in-situ thermal stresses to achieve a +/-5°F accuracy of Neutral Temperature determination with a 90% statistical confidence, which is the desired industry gold standard.

  15. Numerical Study of Thermal Stresses for the Semiconductor CdZnTe in Vertical Bridgman

    OpenAIRE

    Jamai , Hanen; El Ganaoui , M.; Sammouda , Habib; Pateyron , Bernard

    2015-01-01

    International audience; The aim of this work is to present a numerical simulation of thermal stress in directional solidification of CdZnTe in vertical Bridgman apparatus. Especial attention will be attributed to show the importance of cooling temperature and time's growth affecting the thermal stress. Furthermore, we will focus on investigating the thermal stress' components and their distribution in crystal, which gives a detailed about the stress distribution and consequently on the distri...

  16. The Mitochondrial Lon Protease Is Required for Age-Specific and Sex-Specific Adaptation to Oxidative Stress.

    Science.gov (United States)

    Pomatto, Laura C D; Carney, Caroline; Shen, Brenda; Wong, Sarah; Halaszynski, Kelly; Salomon, Matthew P; Davies, Kelvin J A; Tower, John

    2017-01-09

    Multiple human diseases involving chronic oxidative stress show a significant sex bias, including neurodegenerative diseases, cancer, immune dysfunction, diabetes, and cardiovascular disease. However, a possible molecular mechanism for the sex bias in physiological adaptation to oxidative stress remains unclear. Here, we report that Drosophila melanogaster females but not males adapt to hydrogen peroxide stress, whereas males but not females adapt to paraquat (superoxide) stress. Stress adaptation in each sex requires the conserved mitochondrial Lon protease and is associated with sex-specific expression of Lon protein isoforms and proteolytic activity. Adaptation to oxidative stress is lost with age in both sexes. Transgenic expression of transformer gene during development transforms chromosomal males into pseudo-females and confers the female-specific pattern of Lon isoform expression, Lon proteolytic activity induction, and H 2 O 2 stress adaptation; these effects were also observed using adult-specific transformation. Conversely, knockdown of transformer in chromosomal females eliminates the female-specific Lon isoform expression, Lon proteolytic activity induction, and H 2 O 2 stress adaptation and produces the male-specific paraquat (superoxide) stress adaptation. Sex-specific expression of alternative Lon isoforms was also observed in mouse tissues. The results develop Drosophila melanogaster as a model for sex-specific stress adaptation regulated by the Lon protease, with potential implications for understanding sexual dimorphism in human disease. Copyright © 2017 Elsevier Ltd. All rights reserved.

  17. What molecular mechanism is adapted by plants during salt stress ...

    African Journals Online (AJOL)

    What molecular mechanism is adapted by plants during salt stress tolerance? ... Salt stress harmfully shocks agricultural yield throughout the world affecting production whether it is for subsistence or economic outcomes. ... from 32 Countries:.

  18. Numerical evaluation of stress intensity factor for vessel and pipe subjected to thermal shock

    International Nuclear Information System (INIS)

    Kim, Y.W.; Lee, H.Y.; Yoo, B.

    1994-01-01

    The thermal weight function method and the finite element method were employed in the numerical computation of the stress intensity factor for a cracked vessel and the cracked pipe subjected to thermal shock. A wall subjected to thermal shock was analyzed, and it has been shown that the effect of thermal shock on the stress intensity factor is dominant for the crack with small crack length to thickness ratio. Convection at the crack face had an influence on the stress intensity factor in the early stage of thermal shock. (Author)

  19. Numerical simulations on the temperature gradient and thermal stress of a thermoelectric power generator

    International Nuclear Information System (INIS)

    Wu, Yongjia; Ming, Tingzhen; Li, Xiaohua; Pan, Tao; Peng, Keyuan; Luo, Xiaobing

    2014-01-01

    Highlights: • An appropriate ceramic plate thickness is effective in alleviating the thermal stress. • A smaller distance between thermo-pins can help prolong lifecycle of the TE module. • Either a thicker or a thinner copper conducting strip effectively reduces thermal stress. • A suitable tin soldering thickness will alleviate thermal stress intensity and increase thermal efficiency. - Abstract: Thermoelectric generator is a device taking advantage of the temperature difference in thermoelectric material to generate electric power, where the higher the temperature difference of the hot-cold ends, the higher the efficiency will be. However, higher temperature or higher heat flux upon the hot end will cause strong thermal stress which will negatively influence the lifecycle of the thermoelectric module. This phenomenon is very common in industrial applications but seldom has research work been reported. In this paper, numerical analysis on the thermodynamics and thermal stress performance of the thermoelectric module has been performed, considering the variation on the thickness of materials; the influence of high heat flux on thermal efficiency, power output, and thermal stress has been examined. It is found that under high heat flux imposing upon the hot end, the thermal stress is so strong that it has a decisive effect on the life expectation of the device. To improve the module’s working condition, different geometrical configurations are tested and the optimum sizes are achieved. Besides, the side effects on the efficiency, power output, and open circuit voltage output of the thermoelectric module are taken into consideration

  20. Adaptation of thermal power plants: The (ir)relevance of climate (change) information

    International Nuclear Information System (INIS)

    Bogmans, Christian W.J.; Dijkema, Gerard P.J.; Vliet, Michelle T.H. van

    2017-01-01

    When does climate change information lead to adaptation? We analyze thermal power plant adaptation by means of investing in water-saving (cooling) technology to prevent a decrease in plant efficiency and load reduction. A comprehensive power plant investment model, forced with downscaled climate and hydrological projections, is then numerically solved to analyze the adaptation decisions of a selection of real power plants. We find that operators that base their decisions on current climatic conditions are likely to make identical choices and perform just as well as operators that are fully ‘informed’ about climate change. Where electricity supply is mainly generated by thermal power plants, heat waves, droughts and low river flow may impact electricity supply for decades to come. - Highlights: • We analyze adaptation to climate change by thermal power plants. • A numerical investment model is applied to a coal plant and a nuclear power plant. • The numerical analysis is based on climate and hydrological projections. • Climate change information has a relatively small effect on a power plant's NPV. • Uncertainty and no-regret benefits lower the value of climate change information.

  1. Implementation and Development of the Incremental Hole Drilling Method for the Measurement of Residual Stress in Thermal Spray Coatings

    Science.gov (United States)

    Valente, T.; Bartuli, C.; Sebastiani, M.; Loreto, A.

    2005-12-01

    The experimental measurement of residual stresses originating within thick coatings deposited by thermal spray on solid substrates plays a role of fundamental relevance in the preliminary stages of coating design and process parameters optimization. The hole-drilling method is a versatile and widely used technique for the experimental determination of residual stress in the most superficial layers of a solid body. The consolidated procedure, however, can only be implemented for metallic bulk materials or for homogeneous, linear elastic, and isotropic materials. The main objective of the present investigation was to adapt the experimental method to the measurement of stress fields built up in ceramic coatings/metallic bonding layers structures manufactured by plasma spray deposition. A finite element calculation procedure was implemented to identify the calibration coefficients necessary to take into account the elastic modulus discontinuities that characterize the layered structure through its thickness. Experimental adjustments were then proposed to overcome problems related to the low thermal conductivity of the coatings. The number of calculation steps and experimental drilling steps were finally optimized.

  2. Thermal and cardiorespiratory newborn adaptations during hot tub bath

    Directory of Open Access Journals (Sweden)

    Gentil Gomes da Fonseca Filho

    2017-03-01

    Full Text Available Objective: To evaluate thermal and cardiorespiratory adaptation during hot tub bath and shower in healthy newborns in the first hours of life. Study design: This is a randomized blind controlled trial, registered in ReBEC (No. RBR-4z26f3 with 184 newborns divided into hot tub group (n=84 and shower (n=100. Newborns from intervention group were immersed in a hot tub with warm water up to the neck, without exposure to air flow, and control group received traditional shower. Heart rate, respiratory rate and temperature were measured before and immediately after bath by an investigator blinded to the type of bath. Results: Groups were similar in gender, gestational age, birth weight, Apgar score at 5th minute and hours of life, p => 0.05. To analyze thermal and cardiorespiratory adjustments, difference between post-bath variables and pre-bath was calculated. In this analysis, it was found statistically significant difference between two types of bath regarding heart rate, respiratory rate and temperature. Hot tub bath decreases heart and respiratory rates and increases temperature, whereas shower provides the opposite effect (0.0001. Conclusion: This study demonstrates that hot tub baths and shower, in healthy newborns, promote thermal and cardiorespiratory adaptations, reflecting thermal, cardiac and respiratory positive reactions after hot tub bath.

  3. Contribution of silent mutations to thermal adaptation of RNA bacteriophage Qβ.

    Science.gov (United States)

    Kashiwagi, Akiko; Sugawara, Ryu; Sano Tsushima, Fumie; Kumagai, Tomofumi; Yomo, Tetsuya

    2014-10-01

    Changes in protein function and other biological properties, such as RNA structure, are crucial for adaptation of organisms to novel or inhibitory environments. To investigate how mutations that do not alter amino acid sequence may be positively selected, we performed a thermal adaptation experiment using the single-stranded RNA bacteriophage Qβ in which the culture temperature was increased from 37.2°C to 41.2°C and finally to an inhibitory temperature of 43.6°C in a stepwise manner in three independent lines. Whole-genome analysis revealed 31 mutations, including 14 mutations that did not result in amino acid sequence alterations, in this thermal adaptation. Eight of the 31 mutations were observed in all three lines. Reconstruction and fitness analyses of Qβ strains containing only mutations observed in all three lines indicated that five mutations that did not result in amino acid sequence changes but increased the amplification ratio appeared in the course of adaptation to growth at 41.2°C. Moreover, these mutations provided a suitable genetic background for subsequent mutations, altering the fitness contribution from deleterious to beneficial. These results clearly showed that mutations that do not alter the amino acid sequence play important roles in adaptation of this single-stranded RNA virus to elevated temperature. Recent studies using whole-genome analysis technology suggested the importance of mutations that do not alter the amino acid sequence for adaptation of organisms to novel environmental conditions. It is necessary to investigate how these mutations may be positively selected and to determine to what degree such mutations that do not alter amino acid sequences contribute to adaptive evolution. Here, we report the roles of these silent mutations in thermal adaptation of RNA bacteriophage Qβ based on experimental evolution during which Qβ showed adaptation to growth at an inhibitory temperature. Intriguingly, four synonymous mutations and

  4. Effect of fin attachment on thermal stress reduction of exhaust manifold of an off road diesel engine

    Institute of Scientific and Technical Information of China (English)

    Ali; Akbar; Partoaa; Morteza; Abdolzadeh; Masoud; Rezaeizadeh

    2017-01-01

    The effect of fin attachment on the thermal stress reduction of exhaust manifold of an off road diesel engine(Komatsu HD325-6) was investigated.For doing this,coupled thermo-fluid-solid analysis of exhaust manifold of the off road diesel engine was carried out.The thermal analysis,including thermal flow,thermal stress,and the thermal deformation of the manifold was investigated.The flow inside the manifold was simulated and then its properties including velocity,pressure,and temperature were obtained.The flow properties were transferred to the solid model and then the thermal stresses and the thermal deformations of the manifold under different operating conditions were calculated.Finally,based on the predicted thermal stresses and thermal deformations of the manifold body shell,two fin types as well as body shell thickness increase were applied in the critical induced thermal stress area of the manifold to reduce the thermal stress and thermal deformation.The results of the above modifications show that the combined modifications,i.e.the thickness increase and the fin attachment,decrease the thermal stresses by up to 28% and the contribution of the fin attachment in this reduction is much higher compared to the shell thickness increase.

  5. Investigation of effective factors of transient thermal stress of the MONJU-System components

    Energy Technology Data Exchange (ETDEWEB)

    Inoue, Masaaki; Hirayama, Hiroshi; Kimura, Kimitaka; Jinbo, M. [Toshiba Corp., Kawasaki, Kanagawa (Japan)

    1999-03-01

    Transient thermal stress of each system Component in the fast breeder reactor is an uncertain factor on it's structural design. The temperature distribution in a system component changes over a wide range in time and in space. An unified evaluation technique of thermal, hydraulic, and structural analysis, in which includes thermal striping, temperature stratification, transient thermal stress and the integrity of the system components, is required for the optimum design of tho fast reactor plant. Thermal boundary conditions should be set up by both the transient thermal stress analysis and the structural integrity evaluation of each system component. The reasonable thermal boundary conditions for the design of the MONJU and a demonstration fast reactor, are investigated. The temperature distribution analysis models and the thermal boundary conditions on the Y-piece structural parts of each system component, such as reactor vessel, intermediate heat exchanger, primary main circulation pump, steam generator, superheater and upper structure of reactor core, are illustrated in the report. (M. Suetake)

  6. TPX vacuum vessel transient thermal and stress conditions

    International Nuclear Information System (INIS)

    Feldshteyn, Y.; Dinkevich, S.; Feng, T.; Majumder, D.

    1995-01-01

    The TPX vacuum vessel provides the vacuum boundary for the plasma and the mechanical support for the internal components. Another function of the vacuum vessel is to contain neutron shielding water in the double wall space during normal operation. This double wall space serves as a heat reservoir for the entire vacuum vessel during bakeout. The vacuum vessel and the internal components are subjected to thermal stresses induced by a nonuniform temperature distribution within the structure during bakeout. A successful Conceptual Design Review in March 1993 has established superheated steam as the heating source of the vacuum vessel. A transient bakeout mode of the vacuum vessel and in-vessel components has been analyzed to evaluate transient period duration, proper temperature level, actual thermal stresses and performance of the steam equipment. Thermally, the vacuum vessel structure may be considered as an adiabatic system because it is perfectly insulated by the strong surrounding vacuum and multiple layers of superinsulation. Important aspects of the analysis are described herein

  7. Coupled transient thermo-fluid/thermal-stress analysis approach in a VTBM setting

    International Nuclear Information System (INIS)

    Ying, A.; Narula, M.; Zhang, H.; Abdou, M.

    2008-01-01

    A virtual test blanket module (VTBM) has been envisioned as a utility to aid in streamlining and optimizing the US ITER TBM design effort by providing an integrated multi-code, multi-physics modeling environment. Within this effort, an integrated simulation approach is being developed for TBM design calculations and performance evaluation. Particularly, integrated thermo-fluid/thermal-stress analysis is important for enabling TBM design and performance calculations. In this paper, procedures involved in transient coupled thermo-fluid/thermal-stress analysis are investigated. The established procedure is applied to study the impact of pulsed operational phenomenon on the thermal-stress response of the TBM first wall. A two-way coupling between the thermal strain and temperature field is also studied, in the context of a change in thermal conductivity of the beryllium pebble bed in a solid breeder blanket TBM due to thermal strain. The temperature field determines the thermal strain in beryllium, which in turn changes the temperature field. Iterative thermo-fluid/thermal strain calculations have been applied to both steady-state and pulsed operation conditions. All calculations have been carried out in three dimensions with representative MCAD models, including all the TBM components in their entirety

  8. The effects of location, thermal stress, and residual stress on corner cracks in nozzles with cladding

    International Nuclear Information System (INIS)

    Besuner, P.M.; Cohen, L.M.; McLean, J.L.

    1977-01-01

    The stress intensity factors (Ksub(I)) for corner cracks in a boiling water reactor feedwater nozzle with stainless steel cladding are obtained for loading by internal pressure, and a fluid quench in the nozzle. Conditions with and without residual stress in the component are considered. The residual stress is simulated by means of a reference temperature change. The stress distribution for the uncracked structure is obtained from a three-dimensional finite element model. A three-dimensional influence function (IF) method, in conjunction with the boundary-integral equation method for structural analysis, is employed to compute Ksub(I) values from the uncracked structure's stress distribution. For each type of loading Ksub(I) values are given for cracks at 15 nozzle locations and for six crack depths. Reasonable agreement is noted between calculated and previously published pressure-induced Ksub(I) values. Comparisons are made to determine the effect on Ksub(I) of crack location, thermal stress, and residual stress as compared to pressure stress. For the thermal transient it is shown that Ksub(I) for small crack depths is maximized early in the transient while Ksub(I) for large cracks is maximized later, under steady state conditions. Ksub(I) computations should, therefore, be made for several transient time points and the maximum Ksub(I) for a given crack depth should be used for design analysis. It is concluded that the effects on Ksub(I) of location, thermal stresses, and residual stresses are significant and generally too complex to evalute without advanced numerical procedures. The utilized combination of finite element analysis of the uncracked structure and three-dimensional influence function analysis of the cracked structure is demonstrated

  9. Thermal stress analysis and operational characteristics of a bellows-seal globe valve

    International Nuclear Information System (INIS)

    Kim, Kwang Su; Kim, Youn Jae

    2005-01-01

    Because of design and manufacturing costs, it is important to predict an expected life of bellows with component stresses of bellows as its design factors and material characteristics. In this study, numerical analyses are carried out to elucidate the thermal and flow characteristics with 0.1 m (4 inch) bellows-seal globe valve for high temperature (max. 600 .deg. C) and for high pressure (max. 104 kgf/cm 2 , 10.2 MPa) conditions. Using commercial codes, FLUENT, which uses FVM and SIMPLE algorithm, and ANSYS, which uses FEM, the pressure and temperature fields are calculated and the results are graphically depicted. In addition, when bellows have an axial displacement, thermal stress affecting bellows life is studied. The pressure and temperature values obtained from the flow analyses are adopted as the boundary conditions for thermal stress analyses. As the result of this study, we get the reasonable coefficients for valve and thermal stress for bellows, compared with existing coefficients and calculated values

  10. Thermal and mechanical stresses in a functionally graded thick sphere

    International Nuclear Information System (INIS)

    Eslami, M.R.; Babaei, M.H.; Poultangari, R.

    2005-01-01

    In this paper, a general solution for the one-dimensional steady-state thermal and mechanical stresses in a hollow thick sphere made of functionally graded material is presented. The temperature distribution is assumed to be a function of radius, with general thermal and mechanical boundary conditions on the inside and outside surfaces of the sphere. The material properties, except Poisson's ratio, are assumed to vary along the radius r according to a power law function. The analytical solution of the heat conduction equation and the Navier equation lead to the temperature profile, radial displacement, radial stress, and hoop stress as a function of radial direction

  11. Analytical method for thermal stress analysis of plasma facing materials

    Science.gov (United States)

    You, J. H.; Bolt, H.

    2001-10-01

    The thermo-mechanical response of plasma facing materials (PFMs) to heat loads from the fusion plasma is one of the crucial issues in fusion technology. In this work, a fully analytical description of the thermal stress distribution in armour tiles of plasma facing components is presented which is expected to occur under typical high heat flux (HHF) loads. The method of stress superposition is applied considering the temperature gradient and thermal expansion mismatch. Several combinations of PFMs and heat sink metals are analysed and compared. In the framework of the present theoretical model, plastic flow and the effect of residual stress can be quantitatively assessed. Possible failure features are discussed.

  12. Analytical method for thermal stress analysis of plasma facing materials

    International Nuclear Information System (INIS)

    You, J.H.; Bolt, H.

    2001-01-01

    The thermo-mechanical response of plasma facing materials (PFMs) to heat loads from the fusion plasma is one of the crucial issues in fusion technology. In this work, a fully analytical description of the thermal stress distribution in armour tiles of plasma facing components is presented which is expected to occur under typical high heat flux (HHF) loads. The method of stress superposition is applied considering the temperature gradient and thermal expansion mismatch. Several combinations of PFMs and heat sink metals are analysed and compared. In the framework of the present theoretical model, plastic flow and the effect of residual stress can be quantitatively assessed. Possible failure features are discussed

  13. Transient thermal stresses in an orthotropic finite rectangular plate due to arbitrary surface heat-generations

    International Nuclear Information System (INIS)

    Sugano, Y.

    1980-01-01

    The transient thermal stresses in an orthotropic finite rectangular plate due to arbitrary surface heat-generations on two edges are studied by means of the Airy stress function. The purposes of this paper are to present a method of determing the transient thermal stresses in an orthographic rectangular plate with four edges of distinct thermal boundary condition of the third kind which exactly satisfy the traction-free conditions of shear stress over all boundaries including four corners of the plate, and to consider the effects of the anisotropies of material properties and the convective heat transfer on the upper and lower surfaces on the thermal stress distribution. (orig.)

  14. Thermal adaptation in Drosophila serrata under conditions linked to ...

    Indian Academy of Sciences (India)

    Unknown

    Centre for Environmental Stress and Adaptation Research, La Trobe .... appear to exhibit quiescence, where reproduction is imme- ..... an effect on the wing length of either sex. ..... perature and male territorial success in Drosophila melano-.

  15. Thermal stress relieving of dilute uranium alloys

    International Nuclear Information System (INIS)

    Eckelmeyer, K.H.

    1980-01-01

    The kinetics of thermal stress relieving of uranium - 2.3 wt. % niobium, uranium - 2.0 wt. % molybdenum, and uranium - 0.75 wt. % titanium are reported and discussed. Two temperature regimes of stress relieving are observed. In the low temperature regime (T 0 C) the process appears to be controlled by an athermal microplasticity mechanism which can be completely suppressed by prior age hardening. In the high temperature regime (300 0 C 0 C) the process appears to be controlled by a classical diffusional creep mechanism which is strongly dependent on temperature and time. Stress relieving is accelerated in cases where it occurs simultaneously with age hardening. The potential danger of residual stress induced stress corrosion cracking of uranium alloys is discussed. It is shown that the residual stress relief which accompanies age hardening of uranium - 0.75% titanium more than compensates for the reduction in K/sub ISCC/ caused by aging. As a result, age hardening actually decreases the susceptibility of this alloy to residual stress induced stress corrosion cracking

  16. Passive adaptation to stress in adulthood after short-term social instability stress during adolescence in mice.

    Science.gov (United States)

    de Lima, A P N; Massoco, C O

    2017-05-01

    This study reports that short-term social instability stress (SIS) in adolescence increases passive-coping in adulthood in male mice. Short-term SIS decreased the latency of immobility and increased the frequency and time of immobility in tail suspension test. These findings support the hypothesis that adolescent stress can induce a passive adaptation to stress in adulthood, even if it is a short period of stress.

  17. Pipe cracking due to thermal stresses produced by valve opening

    International Nuclear Information System (INIS)

    Sanchez Sarmiento, G.

    1982-01-01

    The thermal stresses produced in a tube whose internal surface is abrupt cooled during a valve opening so that the water volume increases linearly with time are studied. A general solution for these stresses and its stress intensity factors in terms of non-dimensional parameters is presented. (E.G.) [pt

  18. Temperature and thermal stress analysis of a switching tube anode

    International Nuclear Information System (INIS)

    Sutton, S.B.

    1979-01-01

    In the design of high power density switching tubes which are subjected to cyclic thermal loads, the temperature induced stresses must be minimized in order to maximize the life expectancy of the tube. Following are details of an analysis performed for the Magnetic Fusion Program at the Lawrence Livermore Laboratory on a proposed tube. The tube configuration is given. The problem was simplified to one-dimensional approximations for both the thermal and stress analyses. The underlying assumptions and their implications are discussed

  19. Effect of walking stress on growth, physiological adaptability and endocrine responses in Malpura ewes in a semi-arid tropical environment

    Science.gov (United States)

    Sejian, Veerasamy; Maurya, Vijai P.; Naqvi, Syed M. K.

    2012-03-01

    Sheep in hot semi-arid environments are mostly reared using extensive systems. In addition to thermal stress and feed scarcity, the animals need to walk long distances for grazing in this ecological zone. A study was conducted to assess the effect of long-distance walking on adaptive capability in terms of physiological, biochemical and endocrine responses in Malpura ewes. Fourteen adult Malpura non-pregnant ewes weighing between 33 and 35 kg were used in the study. The ewes were randomly allocated into two groups of seven animals each: GI ( n = 7; Control), and GII ( n = 7; walking stress). The animals were stall-fed with a diet consisting of 70% roughage and 30% concentrate. Both GI and GII ewes had uniform access to feed and water. The walking stress group (GII) ewes were made to walk 14 km in two spans between 0900 and 1500 hours with 1 h 30 min for each span (7 km) of walking. The ewes subjected to walking stress (GII) were prevented from grazing by applying a face mask made of cotton thread. The study was conducted for a period of two estrous cycles (35 days) during the autumn season (October-November). Physiological responses were recorded twice daily at 0800 and 1400 hours at weekly intervals. Blood samples were collected from the jugular vein at weekly intervals to study the effects of walking stress on blood biochemical and endocrine parameters. The results indicate that walking stress had significant ( P ewes have the capability to adapt to long-distance walking, and that adrenal and thyroid gland hormones play a significant role in such adaptation.

  20. Combined thermal and herbicide stress in functionally diverse coral symbionts

    International Nuclear Information System (INIS)

    Dam, J.W. van; Uthicke, S.; Beltran, V.H.; Mueller, J.F.; Negri, A.P.

    2015-01-01

    Most reef building corals rely on symbiotic microalgae (genus Symbiodinium) to supply a substantial proportion of their energy requirements. Functional diversity of different Symbiodinium genotypes, endorsing the host with physiological advantages, has been widely reported. Yet, the influence of genotypic specificity on the symbiont's susceptibility to contaminants or cumulative stressors is unknown. Cultured Symbiodinium of presumed thermal-tolerant clade D tested especially vulnerable to the widespread herbicide diuron, suggesting important free-living populations may be at risk in areas subjected to terrestrial runoff. Co-exposure experiments where cultured Symbiodinium were exposed to diuron over a thermal stress gradient demonstrated how fast-growing clade C1 better maintained photosynthetic capability than clade D. The mixture toxicity model of Independent Action, considering combined thermal stress and herbicide contamination, revealed response additivity for inhibition of photosynthetic yield in both tested cultures, emphasizing the need to account for cumulative stressor impacts in ecological risk assessment and resource management. - Highlights: • Water quality influences thermal stress thresholds in different Symbiodinium types. • Photosystem of clade D tested more sensitive than C1 to a common herbicide. • Increased thermal tolerance quickly countered in presence of herbicide. • Mixture toxicity approach demonstrated response additivity for combined stressors. • Symbiotic partnership may be compromised in areas subjected to terrestrial runoff. - Thermal-tolerant Symbiodinium type D tested especially vulnerable to a common herbicide, emphasizing the significance of cumulative stressors in ecological risk management

  1. Damage assessment of low-cycle fatigue by crack growth prediction. Fatigue life under cyclic thermal stress

    International Nuclear Information System (INIS)

    Kamaya, Masayuki

    2013-01-01

    The number of cycles to failure of specimens in fatigue tests can be estimated by predicting crack growth. Under a cyclic thermal stress caused by fluctuation of fluid temperature, due to the stress gradient in the thickness direction, the estimated fatigue life differs from that estimated for mechanical fatigue tests. In this paper, the influence of crack growth under cyclic thermal loading on the fatigue life was investigated. First, the thermal stress was derived by superposing analytical solutions, and then, the stress intensity factor was obtained by the weight function method. It was shown that the thermal stress depended not on the rate of the fluid temperature change but on the rise time, and the magnitude of the stress was increased as the rise time was decreased. The stress intensity factor under the cyclic thermal stress was smaller than that under the uniform stress distribution. The change in the stress intensity factor with the crack depth was almost the same regardless of the rise time. The estimated fatigue life under the cyclic thermal loading could be 1.6 times longer than that under the uniform stress distribution. The critical size for the fatigue life determination was assumed to be 3 mm for fatigue test specimens of 10 mm diameter. By evaluating the critical size by structural integrity analyses, the fatigue life was increased and the effect of the critical size on the fatigue life was more pronounced for the cyclic thermal stress. (author)

  2. Work Stress Adaptation: Roles of Gender, Social Support and ...

    African Journals Online (AJOL)

    Workers in Nigeria are faced with many stress factors such as work-related, domestic, after job, age or retirement problem to cope with or managed. In view of this, the present study examined the effects of gender, social support and personality (Type A and Type B) on work stress adaptation. Using random and accidental ...

  3. Physiology-driven adaptive virtual reality stimulation for prevention and treatment of stress related disorders.

    Science.gov (United States)

    Cosić, Kresimir; Popović, Sinisa; Kukolja, Davor; Horvat, Marko; Dropuljić, Branimir

    2010-02-01

    The significant proportion of severe psychological problems related to intensive stress in recent large peacekeeping operations underscores the importance of effective methods for strengthening the prevention and treatment of stress-related disorders. Adaptive control of virtual reality (VR) stimulation presented in this work, based on estimation of the person's emotional state from physiological signals, may enhance existing stress inoculation training (SIT). Physiology-driven adaptive VR stimulation can tailor the progress of stressful stimuli delivery to the physiological characteristics of each individual, which is indicated for improvement in stress resistance. Following an overview of physiology-driven adaptive VR stimulation, its major functional subsystems are described in more detail. A specific algorithm of stimuli delivery applicable to SIT is outlined.

  4. First wall thermal stress analysis for suddenly applied heat fluxes

    International Nuclear Information System (INIS)

    Dalessandro, J.A.

    The failure criterion for a solid first wall of an inertial confinement reactor is investigated. Analytical expressions for induced thermal stresses in a plate are given. Two materials have been chosen for this investigation: grade H-451 graphite and chemically vapor deposited (CVD) β-silicon carbide. Structural failure can be related to either the maximum compressive stress produced on the surface or the maximum tensile stress developed in the interior of the plate; however, it is shown that compressive failure would predominate. A basis for the choice of the thermal shock figure of merit, k(1 - ν) sigma/E α kappa/sup 1/2/, is identified. The result is that graphite and silicon carbide rank comparably

  5. Human power output during repeated sprint cycle exercise: the influence of thermal stress

    NARCIS (Netherlands)

    Ball, D.; Burrows, C.; Sargeant, A.J.

    1999-01-01

    Thermal stress is known to impair endurance capacity during moderate prolonged exercise. However, there is relatively little available information concerning the effects of thermal stress on the performance of high-intensity short-duration exercise. The present experiment examined human power output

  6. Thermal residual stress evaluation based on phase-shift lateral shearing interferometry

    Science.gov (United States)

    Dai, Xiangjun; Yun, Hai; Shao, Xinxing; Wang, Yanxia; Zhang, Donghuan; Yang, Fujun; He, Xiaoyuan

    2018-06-01

    An interesting phase-shift lateral shearing interferometry system was proposed to evaluate the thermal residual stress distribution in transparent specimen. The phase-shift interferograms was generated by moving a parallel plane plate. Based on analyzing the fringes deflected by deformation and refractive index change, the stress distribution can be obtained. To verify the validity of the proposed method, a typical experiment was elaborately designed to determine thermal residual stresses of a transparent PMMA plate subjected to the flame of a lighter. The sum of in-plane stress distribution was demonstrated. The experimental data were compared with values measured by digital gradient sensing method. Comparison of the results reveals the effectiveness and feasibility of the proposed method.

  7. Thermal stresses at nozzles of nuclear steel containments under LOCA-conditions

    International Nuclear Information System (INIS)

    Sanchez Sarmiento, G.; Bergmann, A.N.

    1986-01-01

    During a loss of coolant accident (LOCA) of a PWR-nuclear power plant, a considerable heating of the containment atmosphere is expected to occur. Transient thermal stresses will appear at the containment as a consequence of a non-uniform rise of its temperature. Applying computer codes based on the finite element method, dimensionless general thermal stresses at nozzles of spherical steel containment have been calculated, varying the principal geometrical parameters and the Biot number for the containment internal surface. Atmosphere temperature and Biot number are assumed constant after the accident. Several plots of the maximum principal stresses are provided, which constitute general results applicable to stress analysis of any particular containment of this kind. (orig.)

  8. Non-climatic thermal adaptation: implications for species' responses to climate warming.

    Science.gov (United States)

    Marshall, David J; McQuaid, Christopher D; Williams, Gray A

    2010-10-23

    There is considerable interest in understanding how ectothermic animals may physiologically and behaviourally buffer the effects of climate warming. Much less consideration is being given to how organisms might adapt to non-climatic heat sources in ways that could confound predictions for responses of species and communities to climate warming. Although adaptation to non-climatic heat sources (solar and geothermal) seems likely in some marine species, climate warming predictions for marine ectotherms are largely based on adaptation to climatically relevant heat sources (air or surface sea water temperature). Here, we show that non-climatic solar heating underlies thermal resistance adaptation in a rocky-eulittoral-fringe snail. Comparisons of the maximum temperatures of the air, the snail's body and the rock substratum with solar irradiance and physiological performance show that the highest body temperature is primarily controlled by solar heating and re-radiation, and that the snail's upper lethal temperature exceeds the highest climatically relevant regional air temperature by approximately 22°C. Non-climatic thermal adaptation probably features widely among marine and terrestrial ectotherms and because it could enable species to tolerate climatic rises in air temperature, it deserves more consideration in general and for inclusion into climate warming models.

  9. Rock properties and their effect on thermally-induced displacements and stresses

    International Nuclear Information System (INIS)

    Chan, T.; Hood, M.; Board, M.

    1980-02-01

    A discussion is given of the importance of material properties in the finite-element calculations for thermally induced displacements and stresses resulting from a heating experiment in an in-situ granitic rock, at Stripa, Sweden. Comparisons are made between field measurements and finite element method calculations using (1) temperature independent, (2) temperature dependent thermal and thermomechanical properties and (3) in-situ and laboratory measurements for Young's modulus. The calculations of rock displacements are influenced predominantly by the temperature dependence of the thermal expansion coefficient, whereas the dominant factor affecting predictions for rock stresses is the in-situ modulus

  10. Effects of thermal aging and stress triaxiality on PWSCC initiation susceptibility of nickel-based Alloy 600

    Energy Technology Data Exchange (ETDEWEB)

    Yoo, Seung Chang; Choi, Kyoung Joon; Kim, Tae Ho; Kim, Ji Hyun [Dept. of Nuclear Science and Engineering, School of Mechanical and Nuclear Engineering, Ulsan National Institute of Science and Technology, Ulsan (Korea, Republic of)

    2016-10-15

    In present study, effects of thermal aging and triaxial stress were investigated in terms of primary water stress corrosion cracking susceptibility. The thermal aging was applied via heat treatment at 400°C and triaxial stress was applied via notched tensile test specimen. The crack initiation time of each specimen were then measured by direct current potential drop method during slow strain rate test at primary water environment. Alloys with 10 years thermal aging exhibited the highest susceptibility to stress corrosion cracking and asreceived specimen shows lowest susceptibility. The trend was different with triaxial stress applied; 20 years thermal aging specimen shows highest susceptibility and as-received specimen shows lowest. It would be owing to change of precipitate morphology during thermal aging and different activated slip system in triaxial stress state.

  11. Non-Contact Smartphone-Based Monitoring of Thermally Stressed Structures

    Science.gov (United States)

    Ozturk, Turgut; Mas, David; Rizzo, Piervincenzo

    2018-01-01

    The in-situ measurement of thermal stress in beams or continuous welded rails may prevent structural anomalies such as buckling. This study proposed a non-contact monitoring/inspection approach based on the use of a smartphone and a computer vision algorithm to estimate the vibrating characteristics of beams subjected to thermal stress. It is hypothesized that the vibration of a beam can be captured using a smartphone operating at frame rates higher than conventional 30 Hz, and the first few natural frequencies of the beam can be extracted using a computer vision algorithm. In this study, the first mode of vibration was considered and compared to the information obtained with a conventional accelerometer attached to the two structures investigated, namely a thin beam and a thick beam. The results show excellent agreement between the conventional contact method and the non-contact sensing approach proposed here. In the future, these findings may be used to develop a monitoring/inspection smartphone application to assess the axial stress of slender structures, to predict the neutral temperature of continuous welded rails, or to prevent thermal buckling. PMID:29670034

  12. Transient thermal stresses of work roll by coupled thermoelasticity

    Science.gov (United States)

    Lai, W. B.; Chen, T. C.; Weng, C. I.

    1991-01-01

    A numerical method, based on a two-dimensional plane strain model, is developed to predict the transient responses (that include distributions of temperature, thermal deformation, and thermal stress) of work roll during strip rolling by coupled thermoelasticity. The method consists of discretizing the space domain of the problem by finite element method first, and then treating the time domain by implicit time integration techniques. In order to avoid the difficulty in analysis due to relative movement between work roll and its thermal boundary, the energy equation is formulated with respect to a fixed Eulerian reference frame. The effect of thermoelastic coupling term, that is generally disregarded in strip rolling, can be considered and assessed. The influences of some important process parameters, such as rotational speed of the roll and intensity of heat flux, on transient solutions are also included and discussed. Furthermore, since the stress history at any point of the roll in both transient and steady state could be accurately evaluated, it is available to perform the analysis of thermal fatigue for the roll by means of previous data.

  13. Time-dependent analytical thermal model to investigate thermally induced stresses in quasi-CW-pumped laser rods

    CSIR Research Space (South Africa)

    Bernhardi, EH

    2008-01-01

    Full Text Available that determines the temperature and the thermally induced stresses in isotropic rods is presented. Even though the model is developed for isotropic rods, it is shown that it can also be used to accurately estimate the thermal effects in anisotropic rods...

  14. Investigating the adaptive model of thermal comfort for naturally ventilated school buildings in Taiwan

    Science.gov (United States)

    Hwang, Ruey-Lung; Lin, Tzu-Ping; Chen, Chen-Peng; Kuo, Nai-Jung

    2009-03-01

    Divergence in the acceptability to people in different regions of naturally ventilated thermal environments raises a concern over the extent to which the ASHRAE Standard 55 may be applied as a universal criterion of thermal comfort. In this study, the ASHRAE 55 adaptive model of thermal comfort was investigated for its applicability to a hot and humid climate through a long-term field survey performed in central Taiwan among local students attending 14 elementary and high schools during September to January. Adaptive behaviors, thermal neutrality, and thermal comfort zones are explored. A probit analysis of thermal acceptability responses from students was performed in place of the conventional linear regression of thermal sensation votes against operative temperature to investigate the limits of comfort zones for 90% and 80% acceptability; the corresponding comfort zones were found to occur at 20.1-28.4°C and 17.6-30.0°C, respectively. In comparison with the yearly comfort zones recommended by the adaptive model for naturally ventilated spaces in the ASHRAE Standard 55, those observed in this study differ in the lower limit for 80% acceptability, with the observed level being 1.7°C lower than the ASHRAE-recommended value. These findings can be generalized to the population of school children, thus providing information that can supplement ASHRAE Standard 55 in evaluating the thermal performance of naturally ventilated school buildings, particularly in hot-humid areas such as Taiwan.

  15. Primary productivity, heterotrophy, metabolic indicators of stress and interactions in algal-bacterial mat communities affected by a fluctuating thermal regime

    International Nuclear Information System (INIS)

    Tison, D.L.

    1980-01-01

    Thermal habitats in effluent cooling waters from production nuclear reactors at the Savannah River Plant are unlike natural thermal habitats in that reactor operations are periodically halted, exposing the organisms growing in these thermal habitats to ambient temperatures for unpredictable lengths of time. Rates of primary production, glucose heterotrophy, and the composition of algal-bacterial mat communities growing along a thermal gradient from about 50 to 35 0 C during periods of reactor operation were studied. Cyanobacteria were the only photoautotrophs in mat communities above 40 0 C while cyanobacteria and eucaryotic algae comprised the photoautotrophic component of mat communities below 40 0 C. The heterotrophic component of these communities above 40 0 C was made up of stenothermic and eurythermic thermophilic bacteria while both eurythermic thermophiles and mesophilic bacteria were found in communities below 40 0 C. Net CO 2 -fixation rates during thermal conditions dropped after initial exposure to ambient temperatures. After prolonged exposure of the thermal communities to ambient temperatures, adaptation and colonization by mesophilic algae occurred. Rates of glucose utilization under varying degrees of thermal influence suggested that the heterotrophic component may not have been optimally adapted to thermal conditions. During periods of changing thermal conditions, an increase in the percentage extracellular release of photosynthetically fixed 14 CO 2 by cyanobacteria and algae and an increase in the percentage of glucose mineralized (respired) by the heterotrophic component of the mat communities was observed. Results of temperature shift experiments indicated that the short-term response of the photoautotrophic component of these communities to thermal stress was an increase in the percentage of photosynthate released extracellularly

  16. Damage assessment of low-cycle fatigue by crack growth prediction. Fatigue life under cyclic thermal stress

    International Nuclear Information System (INIS)

    Kamaya, Masayuki

    2013-01-01

    The number of cycles to failure of specimens in fatigue tests can be estimated by predicting crack growth. Under a cyclic thermal stress caused by fluctuation of fluid temperature, due to the stress gradient in the thickness direction, the estimated fatigue life differs from that estimated for mechanical fatigue tests. In this paper, the influence of crack growth under cyclic thermal loading on the fatigue life was investigated. First, the thermal stress was derived by superposing analytical solutions, and then, the stress intensity factor was obtained by the weight function method. It was shown that the thermal stress depended not on the rate of the fluid temperature change but on the rise time, and the magnitude of the stress was increased as the rise time was decreased. The stress intensity factor under the cyclic thermal stress was smaller than that under the uniform stress distribution. The change in the stress intensity factor with the crack depth did not depend on the heat transfer coefficient and only slightly depended on the rise time. The estimated fatigue life under the cyclic thermal loading could be 1.6 times longer than that under the uniform stress distribution. The critical size for the fatigue life determination was assumed to be 3 mm for fatigue test specimens of 10 mm diameter. By evaluating the critical size by structural integrity analyses, the fatigue life was increased and the effect of the critical size on the fatigue life was more pronounced for the cyclic thermal stress. (author)

  17. Neurobiology of stress adaptation in the mouse: Roles of corticotropin-releasing factor and urocortin 1

    NARCIS (Netherlands)

    Körösi, Anikó

    2006-01-01

    The body's ability to adapt to stressors is essential for survival. Failure of stress adaptation may lead to the development of stress-related disorders. The traditionally known adaptation system in vertebrates, is the hypothalamo-pituitary-adrenal (HPA-) axis, in which corticotropin-releasing

  18. Expression of genes involved in energy mobilization and osmoprotectant synthesis during thermal and dehydration stress in the Antarctic midge, Belgica antarctica.

    Science.gov (United States)

    Teets, Nicholas M; Kawarasaki, Yuta; Lee, Richard E; Denlinger, David L

    2013-02-01

    The Antarctic midge, Belgica antarctica, experiences sub-zero temperatures and desiccating conditions for much of the year, and in response to these environmental insults, larvae undergo rapid shifts in metabolism, mobilizing carbohydrate energy reserves to promote synthesis of low-molecular-mass osmoprotectants. In this study, we measured the expression of 11 metabolic genes in response to thermal and dehydration stress. During both heat and cold stress, we observed upregulation of phosphoenolpyruvate carboxykinase (pepck) and glycogen phosphorylase (gp) to support rapid glucose mobilization. In contrast, there was a general downregulation of pathways related to polyol, trehalose, and proline synthesis during both high- and low-temperature stress. Pepck was likewise upregulated in response to different types of dehydration stress; however, for many of the other genes, expression patterns depended on the nature of dehydration stress. Following fast dehydration, expression patterns were similar to those observed during thermal stress, i.e., upregulation of gp accompanied by downregulation of trehalose and proline synthetic genes. In contrast, gradual, prolonged dehydration (both at a constant temperature and in conjunction with chilling) promoted marked upregulation of genes responsible for trehalose and proline synthesis. On the whole, our data agree with known metabolic adaptations to stress in B. antarctica, although a few discrepancies between gene expression patterns and downstream metabolite contents point to fluxes that are not controlled at the level of transcription.

  19. Disparate patterns of thermal adaptation between life stages in temperate vs. tropical Drosophila melanogaster.

    Science.gov (United States)

    Lockwood, B L; Gupta, T; Scavotto, R

    2018-02-01

    Many terrestrial ectothermic species exhibit limited variation in upper thermal tolerance across latitude. However, these trends may not signify limited adaptive capacity to increase thermal tolerance in the face of climate change. Instead, thermal tolerance may be similar among populations because behavioural thermoregulation by mobile organisms or life stages may buffer natural selection for thermal tolerance. We compared thermal tolerance of adults and embryos among natural populations of Drosophila melanogaster from a broad range of thermal habitats around the globe to assess natural variation of thermal tolerance in mobile vs. immobile life stages. We found no variation among populations in adult thermal tolerance, but embryonic thermal tolerance was higher in tropical strains than in temperate strains. We further report that embryos live closer to their upper thermal limits than adults - that is, thermal safety margins are smaller for embryos than adults. F1 hybrid embryos from crosses between temperate and tropical populations had thermal tolerance that matched that of tropical embryos, suggesting the dominance of heat-tolerant alleles. Together, our findings suggest that thermal selection has led to divergence in embryonic thermal tolerance but that selection for divergent thermal tolerance may be limited in adults. Further, our results suggest that thermal traits should be measured across life stages to better predict adaptive limits. © 2017 European Society For Evolutionary Biology. Journal of Evolutionary Biology © 2017 European Society For Evolutionary Biology.

  20. Assessment of thermal fatigue damage caused by local fluid temperature fluctuation (part I: characteristics of constraint and stress caused by thermal striation and stratification)

    International Nuclear Information System (INIS)

    Kamaya, Masayuki

    2014-01-01

    Highlights: • The source of the membrane constraint due to local temperature fluctuation was shown. • Thermal fatigue that occurred at a mixing tee and branched elbow was analyzed. • Cracking occurrence was reasonably explained by the constraint and stress conditions. - Abstract: This study was aimed at identifying the constraint conditions under local temperature fluctuation by thermal striping at a mixing tee and by thermal stratification at an elbow pipe branched from the main pipe. Numerical and analytical approaches were made to derive the thermal stress and its fluctuation. It was shown that an inhomogeneous temperature distribution in a straight pipe caused thermal stress due to a membrane constraint even if an external membrane constraint did not act on the pipe. Although the membrane constraint increased the mean stress at the mixing tee, it did not contribute to fluctuation of the thermal stress. On the other hand, the membrane constraint played an important role in the fatigue damage accumulation near the stratification layer of the branched elbow. Based on the constraint and stress conditions analyzed, the characteristics of the cracking observed in actual nuclear power plants were reasonably explained. Namely, at the mixing tee, where thermal crazing has been found, the lack of contribution of the membrane constraint to stress fluctuation caused a stress gradient in the thickness direction and arrested crack growth. On the other hand, at the branched elbow, where axial through-wall cracks have been found, the relatively large hoop stress fluctuation was brought about by movement of the stratified layer together with the membrane constraint even under a relatively low frequency of stress fluctuation

  1. Microstructural evolution and stress-corrosion-cracking behavior of thermally aged Ni-Cr-Fe alloy

    International Nuclear Information System (INIS)

    Yoo, Seung Chang; Choi, Kyoung Joon; Kim, Taeho; Kim, Si Hoon; Kim, Ju Young; Kim, Ji Hyun

    2016-01-01

    Highlights: • Effects of long-term thermal aging on the nickel-based Alloy 600 were investigated. • Heat treatments simulating thermal aging were conducted by considering Cr diffusion. • Nano-indentation test results show hardening of thermally aged materials. • Thermally aged materials are more susceptible to stress corrosion cracking. • The property changes are attributed to the formation and evolution of precipitates. - Abstract: To understand the effect of long-term thermal aging in power plant systems, representative thick-walled Alloy 600 was prepared and thermally aged at 400 °C to fabricate samples with thermal aging effects similar to service operating conditions. Changes of microstructures, mechanical properties, and stress corrosion cracking susceptibility were investigated mainly through electron backscatter diffraction, nanoindentation, and high-temperature slow strain rate test. The formation of abundant semi-continuous precipitates with chromium depletion at grain boundaries was observed after thermally aged for 10 equivalent years. Also, alloys thermally aged for 10 equivalent years of thermal aging exhibited the highest susceptibility to stress corrosion cracking.

  2. Adaptive and Pathogenic Responses to Stress by Stem Cells during Development

    OpenAIRE

    Mansouri, Ladan; Xie, Yufen; Rappolee, Daniel A

    2012-01-01

    Cellular stress is the basis of a dose-dependent continuum of responses leading to adaptive health or pathogenesis. For all cells, stress leads to reduction in macromolecular synthesis by shared pathways and tissue and stress-specific homeostatic mechanisms. For stem cells during embryonic, fetal, and placental development, higher exposures of stress lead to decreased anabolism, macromolecular synthesis and cell proliferation. Coupled with diminished stem cell proliferation is a stress-induce...

  3. Oroxin B selectively induces tumor-suppressive ER stress and concurrently inhibits tumor-adaptive ER stress in B-lymphoma cells for effective anti-lymphoma therapy

    International Nuclear Information System (INIS)

    Yang, Ping; Fu, Shilong; Cao, Zhifei; Liao, Huaidong; Huo, Zihe; Pan, Yanyan; Zhang, Gaochuan; Gao, Aidi; Zhou, Quansheng

    2015-01-01

    Cancer cells have both tumor-adaptive and -suppressive endoplasmic reticulum (ER) stress machineries that determine cell fate. In malignant tumors including lymphoma, constant activation of tumor-adaptive ER stress and concurrent reduction of tumor-suppressive ER stress favors cancer cell proliferation and tumor growth. Current ER stress-based anti-tumor drugs typically activate both tumor-adaptive and -suppressive ER stresses, resulting in low anti-cancer efficacy; hence, selective induction of tumor-suppressive ER stress and inhibition of tumor-adaptive ER stress are new strategies for novel anti-cancer drug discovery. Thus far, specific tumor-suppressive ER stress therapeutics have remained absent in clinical settings. In this study, we explored unique tumor-suppressive ER stress agents from the traditional Chinese medicinal herb Oroxylum indicum, and found that a small molecule oroxin B selectively induced tumor-suppressive ER stress in malignant lymphoma cells, but not in normal cells, effectively inhibited lymphoma growth in vivo, and significantly prolonged overall survival of lymphoma-xenografted mice without obvious toxicity. Mechanistic studies have revealed that the expression of key tumor-adaptive ER-stress gene GRP78 was notably suppressed by oroxin B via down-regulation of up-stream key signaling protein ATF6, while tumor-suppressive ER stress master gene DDIT3 was strikingly activated through activating the MKK3-p38 signaling pathway, correcting the imbalance between tumor-suppressive DDIT3 and tumor-adaptive GRP78 in lymphoma. Together, selective induction of unique tumor-suppressive ER stress and concurrent inhibition of tumor-adaptive ER stress in malignant lymphoma are new and feasible approaches for novel anti-lymphoma drug discovery and anti-lymphoma therapy. - Highlights: • Oroxin B selectively induces tumor-suppressive ER stress in B-lymphoma cells. • Oroxin B significantly prolonged overall survival of lymphoma-xenografted mice.

  4. Oroxin B selectively induces tumor-suppressive ER stress and concurrently inhibits tumor-adaptive ER stress in B-lymphoma cells for effective anti-lymphoma therapy

    Energy Technology Data Exchange (ETDEWEB)

    Yang, Ping; Fu, Shilong; Cao, Zhifei; Liao, Huaidong; Huo, Zihe; Pan, Yanyan; Zhang, Gaochuan; Gao, Aidi; Zhou, Quansheng, E-mail: zhouqs@suda.edu.cn

    2015-10-15

    Cancer cells have both tumor-adaptive and -suppressive endoplasmic reticulum (ER) stress machineries that determine cell fate. In malignant tumors including lymphoma, constant activation of tumor-adaptive ER stress and concurrent reduction of tumor-suppressive ER stress favors cancer cell proliferation and tumor growth. Current ER stress-based anti-tumor drugs typically activate both tumor-adaptive and -suppressive ER stresses, resulting in low anti-cancer efficacy; hence, selective induction of tumor-suppressive ER stress and inhibition of tumor-adaptive ER stress are new strategies for novel anti-cancer drug discovery. Thus far, specific tumor-suppressive ER stress therapeutics have remained absent in clinical settings. In this study, we explored unique tumor-suppressive ER stress agents from the traditional Chinese medicinal herb Oroxylum indicum, and found that a small molecule oroxin B selectively induced tumor-suppressive ER stress in malignant lymphoma cells, but not in normal cells, effectively inhibited lymphoma growth in vivo, and significantly prolonged overall survival of lymphoma-xenografted mice without obvious toxicity. Mechanistic studies have revealed that the expression of key tumor-adaptive ER-stress gene GRP78 was notably suppressed by oroxin B via down-regulation of up-stream key signaling protein ATF6, while tumor-suppressive ER stress master gene DDIT3 was strikingly activated through activating the MKK3-p38 signaling pathway, correcting the imbalance between tumor-suppressive DDIT3 and tumor-adaptive GRP78 in lymphoma. Together, selective induction of unique tumor-suppressive ER stress and concurrent inhibition of tumor-adaptive ER stress in malignant lymphoma are new and feasible approaches for novel anti-lymphoma drug discovery and anti-lymphoma therapy. - Highlights: • Oroxin B selectively induces tumor-suppressive ER stress in B-lymphoma cells. • Oroxin B significantly prolonged overall survival of lymphoma-xenografted mice.

  5. Genetic erosion impedes adaptive responses to stressful environments

    NARCIS (Netherlands)

    Bijlsma, R.; Loeschcke, Volker

    Biodiversity is increasingly subjected to human-induced changes of the environment. To persist, populations continually have to adapt to these often stressful changes including pollution and climate change. Genetic erosion in small populations, owing to fragmentation of natural habitats, is expected

  6. Adaptive phase estimation with squeezed thermal light

    DEFF Research Database (Denmark)

    Berni, A. A.; Madsen, Lars Skovgaard; Lassen, Mikael Østergaard

    2013-01-01

    Summary form only given. The use of quantum states of light in optical interferometry improves the precision in the estimation of a phase shift, paving the way for applications in quantum metrology, computation and cryptography. Sub-shot noise phase sensing can for example be achieved by injecting...... investigate the performances of such protocol under the realistic assumption of thermalization of the probe state. Indeed, adaptive phase estimation schemes with squeezed states and Bayesian processing of homodyne data have been shown to be asymptotically optimal in the pure case, thus approaching the quantum...... Cramér-Rao bound. In our protocol we take advantage of the enhanced sensitivity of homodyne detection in proximity of the optimal phase which maximizes the homodyne Fisher information. A squeezed thermal probe state (signal) undergoes an unknown phase shift. The first estimation step involves...

  7. Transient thermal stress problem for a circumferentially cracked hollow cylinder

    Science.gov (United States)

    Nied, H. F.; Erdogan, F.

    1982-01-01

    The transient thermal stress problem for a hollow elasticity cylinder containing an internal circumferential edge crack is considered. It is assumed that the problem is axisymmetric with regard to the crack geometry and the loading, and that the inertia effects are negligible. The problem is solved for a cylinder which is suddenly cooled from inside. First the transient temperature and stress distributions in an uncracked cylinder are calculated. By using the equal and opposite of this thermal stress as the crack surface traction in the isothermal cylinder the crack problem is then solved and the stress intensity factor is calculated. The numerical results are obtained as a function of the Fourier number tD/b(2) representing the time for various inner-to-outer radius ratios and relative crack depths, where D and b are respectively the coefficient of diffusivity and the outer radius of the cylinder.

  8. Thermal stress intensity factor for an axial crack in a clad cylinder

    International Nuclear Information System (INIS)

    Kuo, An Yu; Deardorf, A.F.; Riccardella, P.C.

    1993-01-01

    Many clad pressure vessels have been found to have cracks running through the inside surface cladding and into the base material. Although Young's moduli and Poisson's ratios of the clad and base materials are about the same for most of the industrial applications, coefficients of thermal expansion of the two dissimilar materials, clad and base materials, are usually quite different. For example, low alloy ferritic steel is a common base material for reactor pressure vessels (RPV) and the vessels are usually clad with austenitic stainless steel. Young's moduli for the low alloy steel and stainless steel at 350 F are 29,000 ksi and 28,000 ksi, respectively, while their coefficients of thermal expansion are 7.47x10 -6 in/in and 9.50x10 -6 in/in-degree F, respectively. The mismatch in coefficients of thermal expansion will cause high residual thermal stress even when the entire vessel is at a uniform temperature. This residual stress is one of the primary reasons why so many cracks have been found in the cladded components. In performing reactor pressure vessel integrity evaluation, such as computing probability of brittle fracture of the RPV, it is necessary to calculate stress intensity factors for cracks, which initiate from the clad material and run into the base metal. This paper presents a convenient method of calculating stress intensity factor for an axial crack emanating from the inside surface of a cladded cylinder under thermal loading. A J-integral like line integral was derived and used to calculate the stress intensity factors from finite element stress solutions of the problem

  9. Tasco®, a Product of Ascophyllum nodosum, Imparts Thermal Stress Tolerance in Caenorhabditis elegans

    Directory of Open Access Journals (Sweden)

    Franklin Evans

    2011-11-01

    Full Text Available Tasco®, a commercial product manufactured from the brown alga Ascophyllum nodosum, has been shown to impart thermal stress tolerance in animals. We investigated the physiological, biochemical and molecular bases of this induced thermal stress tolerance using the invertebrate animal model, Caenorhabiditis elegans. Tasco® water extract (TWE at 300 µg/mL significantly enhanced thermal stress tolerance as well as extended the life span of C. elegans. The mean survival rate of the model animals under thermal stress (35 °C treated with 300 µg/mL and 600 µg/mL TWE, respectively, was 68% and 71% higher than the control animals. However, the TWE treatments did not affect the nematode body length, fertility or the cellular localization of daf-16. On the contrary, TWE under thermal stress significantly increased the pharyngeal pumping rate in treated animals compared to the control. Treatment with TWE also showed differential protein expression profiles over control following 2D gel-electrophoresis analysis. Furthermore, TWE significantly altered the expression of at least 40 proteins under thermal stress; among these proteins 34 were up-regulated while six were down-regulated. Mass spectroscopy analysis of the proteins altered by TWE treatment revealed that these proteins were related to heat stress tolerance, energy metabolism and a muscle structure related protein. Among them heat shock proteins, superoxide dismutase, glutathione peroxidase, aldehyde dehydrogenase, saposin-like proteins 20, myosin regulatory light chain 1, cytochrome c oxidase RAS-like, GTP-binding protein RHO A, OS were significantly up-regulated, while eukaryotic translation initiation factor 5A-1 OS, 60S ribosomal protein L18 OS, peroxiredoxin protein 2 were down regulated by TWE treatment. These results were further validated by gene expression and reporter gene expression analyses. Overall results indicate that the water soluble components of Tasco® imparted thermal stress

  10. Incorporating adaptive responses into future projections of coral bleaching.

    Science.gov (United States)

    Logan, Cheryl A; Dunne, John P; Eakin, C Mark; Donner, Simon D

    2014-01-01

    Climate warming threatens to increase mass coral bleaching events, and several studies have projected the demise of tropical coral reefs this century. However, recent evidence indicates corals may be able to respond to thermal stress though adaptive processes (e.g., genetic adaptation, acclimatization, and symbiont shuffling). How these mechanisms might influence warming-induced bleaching remains largely unknown. This study compared how different adaptive processes could affect coral bleaching projections. We used the latest bias-corrected global sea surface temperature (SST) output from the NOAA/GFDL Earth System Model 2 (ESM2M) for the preindustrial period through 2100 to project coral bleaching trajectories. Initial results showed that, in the absence of adaptive processes, application of a preindustrial climatology to the NOAA Coral Reef Watch bleaching prediction method overpredicts the present-day bleaching frequency. This suggests that corals may have already responded adaptively to some warming over the industrial period. We then modified the prediction method so that the bleaching threshold either permanently increased in response to thermal history (e.g., simulating directional genetic selection) or temporarily increased for 2-10 years in response to a bleaching event (e.g., simulating symbiont shuffling). A bleaching threshold that changes relative to the preceding 60 years of thermal history reduced the frequency of mass bleaching events by 20-80% compared with the 'no adaptive response' prediction model by 2100, depending on the emissions scenario. When both types of adaptive responses were applied, up to 14% more reef cells avoided high-frequency bleaching by 2100. However, temporary increases in bleaching thresholds alone only delayed the occurrence of high-frequency bleaching by ca. 10 years in all but the lowest emissions scenario. Future research should test the rate and limit of different adaptive responses for coral species across latitudes and

  11. Thermal expansion coefficients of obliquely deposited MgF2 thin films and their intrinsic stress.

    Science.gov (United States)

    Jaing, Cheng-Chung

    2011-03-20

    This study elucidates the effects of columnar angles and deposition angles on the thermal expansion coefficients and intrinsic stress behaviors of MgF2 films with columnar microstructures. The behaviors associated with temperature-dependent stresses in the MgF2 films are measured using a phase-shifting Twyman-Green interferometer with a heating stage and the application of a phase reduction algorithm. The thermal expansion coefficients of MgF2 films at various columnar angles were larger than those of glass substrates. The intrinsic stress in the MgF2 films with columnar microstructures was compressive, while the thermal stress was tensile. The thermal expansion coefficients of MgF2 films with columnar microstructures and their intrinsic stress evidently depended on the deposition angle and the columnar angle.

  12. A plant microRNA regulates the adaptation of roots to drought stress

    KAUST Repository

    Chen, Hao

    2012-06-01

    Plants tend to restrict their horizontal root proliferation in response to drought stress, an adaptive response mediated by the phytohormone abscisic acid (ABA) in antagonism with auxin through unknown mechanisms. Here, we found that stress-regulated miR393-guided cleavage of the transcripts encoding two auxin receptors, TIR1 and AFB2, was required for inhibition of lateral root growth by ABA or osmotic stress. Unlike in the control plants, the lateral root growth of seedlings expressing miR393-resistant TIR1 or AFB2 was no longer inhibited by ABA or osmotic stress. Our results indicate that miR393-mediated attenuation of auxin signaling modulates root adaptation to drought stress. © 2012 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.

  13. Survival of juvenile fishes receiving thermal and mechanical stresses in a simulated power plant condenser

    International Nuclear Information System (INIS)

    Kedl, R.J.; Coutant, C.C.

    Experiments were conducted in a water-recirculating loop to determine the effects of fluid-induced stresses (e.g., turbulence, pressure, and vacuum) on six species of larval fish and one species each of frog tadpoles and zooplankton. These stresses simulate the insults developed in the condenser portion, but not including the pump, of a steam power plant. Some experiments were conducted with thermal stresses superimposed on fluid-induced stresses. Fluid-induced stresses of the magnitude developed in these experiments were generally not fatal to the larval fish within the precision of the experiments, although some sublethal effects were noted. When thermal stress was superimposed on the fluid-induced stresses, the mortalities were equivalent to those resulting from thermal stress alone. Fluid-induced stresses of low magnitude were not fatal to Daphnia magna, but fluid-induced stresses of higher magnitude were responsible for significant mortalities. (U.S.)

  14. Transient thermal stresses in composite hollow circular cylinder due to partial heat generation

    International Nuclear Information System (INIS)

    Goshima, Takahito; Miyao, Kaju

    1979-01-01

    Clad materials are adopted for the machines and structures used in contact with high temperature, corrosive atmosphere in view of their strength and economy. Large thermal stress sometimes arises in clad cylinders due to uneaven temperature field and the difference in linear thermal expansion. Vessels are often heated uneavenly, and shearing stress occurs, which is not observed in uniform heating. In this study, infinitely long, concentric cylinders of two layers were analyzed, when the internal heat changing in stepped state is generated in cylindrical form. The unsteady thermal stress occurred was determined, using thermo-elastic potential and stress functions, and assuming the thermal properties and elastic modulus of materials as constant regardless of the temperature. Laplace transformation was used, and the basic equations for thermo-elastic displacement were employed as the basis of calculation. The analysis of the temperature distribution and stress is explained. Numerical calculation was carried out on the example of an internal cylinder of SUS 304 stainless steel and an external cylinder of mild steel. The maximum shearing stress occurred in the direction of 40 deg from the heat source, and was affected largely by the position of heat generation. The effect became remarkable as time elapsed. (Kako, I.)

  15. Effect of thermal stresses on the mechanism of tooth pain.

    Science.gov (United States)

    Oskui, Iman Z; Ashtiani, Mohammed N; Hashemi, Ata; Jafarzadeh, Hamid

    2014-11-01

    Daily hot and cold thermal loadings on teeth may result in structural deformation, mechanical stress, and pain signaling. The aim of this study was to compare the adverse effects of hot and cold beverages on an intact tooth and, then, to provide physical evidence to support the hydrodynamic theory of tooth pain sensation mechanism. Three-dimensional finite element analysis was performed on a premolar model subjected to hot and cold thermal loadings. Elapsed times for heat diffusion and stress detection at the pulp-dentin junction were calculated as measures of the pain sensation. Extreme tensile stress within the enamel resulted in damage in cold loadings. Also, extreme values of stress at the pulpal wall occurred 21.6 seconds earlier than extreme temperatures in hot and cold loadings. The intact tooth was remarkably vulnerable to cold loading. Earlier changes in mechanical stress rather than temperature at the pulp-dentin junction indicate that the dental pain caused by hot or cold beverages may be based on the hydrodynamic theory. Copyright © 2014 American Association of Endodontists. Published by Elsevier Inc. All rights reserved.

  16. Stress analysis in curved composites due to thermal loading

    Science.gov (United States)

    Polk, Jared Cornelius

    Many structures in aircraft, cars, trucks, ships, machines, tools, bridges, and buildings, consist of curved sections. These sections vary from straight line segments that have curvature at either one or both ends, segments with compound curvatures, segments with two mutually perpendicular curvatures or Gaussian curvatures, and segments with a simple curvature. With the advancements made in multi-purpose composites over the past 60 years, composites slowly but steadily have been appearing in these various vehicles, compound structures, and buildings. These composite sections provide added benefits over isotropic, polymeric, and ceramic materials by generally having a higher specific strength, higher specific stiffnesses, longer fatigue life, lower density, possibilities in reduction of life cycle and/or acquisition cost, and greater adaptability to intended function of structure via material composition and geometry. To be able to design and manufacture a safe composite laminate or structure, it is imperative that the stress distributions, their causes, and effects are thoroughly understood in order to successfully accomplish mission objectives and manufacture a safe and reliable composite. The objective of the thesis work is to expand upon the knowledge of simply curved composite structures by exploring and ascertaining all pertinent parameters, phenomenon, and trends in stress variations in curved laminates due to thermal loading. The simply curved composites consist of composites with one radius of curvature throughout the span of the specimen about only one axis. Analytical beam theory, classical lamination theory, and finite element analysis were used to ascertain stress variations in a flat, isotropic beam. An analytical method was developed to ascertain the stress variations in an isotropic, simply curved beam under thermal loading that is under both free-free and fixed-fixed constraint conditions. This is the first such solution to Author's best knowledge

  17. Mosaic-shaped cathode for highly durable solid oxide fuel cell under thermal stress

    Science.gov (United States)

    Joo, Jong Hoon; Jeong, Jaewon; Kim, Se Young; Yoo, Chung-Yul; Jung, Doh Won; Park, Hee Jung; Kwak, Chan; Yu, Ji Haeng

    2014-02-01

    In this study, we propose a novel "mosaic structure" for a SOFC (solid oxide fuel cell) cathode with high thermal expansion to improve the stability against thermal stress. Self-organizing mosaic-shaped cathode has been successfully achieved by controlling the amount of binder in the dip-coating solution. The anode-supported cell with mosaic-shaped cathode shows itself to be highly durable performance for rapid thermal cycles, however, the performance of the cell with a non-mosaic cathode exhibits severe deterioration originated from the delamination at the cathode/electrolyte interface after 7 thermal cycles. The thermal stability of an SOFC cathode can be evidently improved by controlling the surface morphology. In view of the importance of the thermal expansion properties of the cathode, the effects of cathode morphology on the thermal stress stability are discussed.

  18. Adaptation des semis de Pin pignon ( Pinus pinea L.) au stress ...

    African Journals Online (AJOL)

    Adaptation des semis de Pin pignon ( Pinus pinea L.) au stress combiné hydrique et thermique par des marqueurs biochimiques. ... Objectif: L'objectif de ce travail consiste à analyser les effets d'un stress hydrique et ... from 32 Countries:.

  19. Transient thermal stresses in multiple connected region exhibiting temperature dependence of material properties

    International Nuclear Information System (INIS)

    Sugano, Yoshihiro; Maekawa, Toshiya.

    1983-01-01

    The examples of the analysis of thermal stress in multiple connection regions such as heat exchangers, nuclear reactor cores, ingot cases and polygonal region with elliptic holes are not few, but the temperature dependence of material constants was neglected in these researches because of the difficulty of analysis though the industrial problems related to thermal stress are apt to occur in the condition of relatively large temperature gradient. Also, the analysis of heat conduction problems taking the temperature dependence of material constants into account was limited to one-dimensional problems for which Kirchhoff's transmission can be used. The purpose of this study is to derive the equation of condition which assures the one-value property of rotation and displacement, taking the temperature dependence of material constants into account, and to complete the formulation of the plane thermal stress problems in multiple connection regions by stress function method. Also the method of numerical analysis using difference method is shown to examine the effectiveness of various formulated equations and the effect of the temperature dependence of material constants on temperature and thermal stress. The example of numerical calculation on a thin rectangular plate with a rectangular hole is shown. (Kako, I.)

  20. Coupling analysis of the target temperature and thermal stress due to pulsed ion beam

    International Nuclear Information System (INIS)

    Yan Jie; Liu Meng; Lin Jufang; An Li; Long Xinggui

    2013-01-01

    Background: Target temperature has an important effect on the target life for the sealed neutron generator without cooling system. Purpose: To carry out the thermal-mechanical coupling analysis of the film-substrate target bombarded by the pulsed ion beam. Methods: The indirect coupling Finite Element Method (FEM) with a 2-dimensional time-space Gaussian axisymmetric power density as heat source was used to simulate the target temperature and thermal stress fields. Results: The effects of the target temperature and thermal stress fields under difference pulse widths and beam sizes were analyzed in terms of the FEM results. Conclusions: Combining with the temperature requirement and the thermal stress inducing film thermal mechanical destruction effect of the sealed neutron generator film-substrate targets, an optimized pulsed ion beam work status was proposed. (authors)

  1. Thermal stresses and cyclic creep-fatigue in fusion reactor blanket

    International Nuclear Information System (INIS)

    Liu, K.C.

    1977-01-01

    Thermal stresses in the first walls of fusion reactor blankets were studied in detail. ORNL multibucket modules are emphasized. Practicality of using the bucket module rather than other blanket designs is examined. The analysis shows that applying intelligent engineering judgment in design can reduce the thermal stresses significantly. Arrangement of coolant flow and distribution of temperature are reviewed. Creep-fatigue property requirements for a first wall are discussed on the basis of existing design rules and criteria. Some major questions are pointed out and experiments needed to resolve basic uncertainties relative to key design decisions are discussed

  2. Design optimization and analysis of selected thermal devices using self-adaptive Jaya algorithm

    International Nuclear Information System (INIS)

    Rao, R.V.; More, K.C.

    2017-01-01

    Highlights: • Self-adaptive Jaya algorithm is proposed for optimal design of thermal devices. • Optimization of heat pipe, cooling tower, heat sink and thermo-acoustic prime mover is presented. • Results of the proposed algorithm are better than the other optimization techniques. • The proposed algorithm may be conveniently used for the optimization of other devices. - Abstract: The present study explores the use of an improved Jaya algorithm called self-adaptive Jaya algorithm for optimal design of selected thermal devices viz; heat pipe, cooling tower, honeycomb heat sink and thermo-acoustic prime mover. Four different optimization case studies of the selected thermal devices are presented. The researchers had attempted the same design problems in the past using niched pareto genetic algorithm (NPGA), response surface method (RSM), leap-frog optimization program with constraints (LFOPC) algorithm, teaching-learning based optimization (TLBO) algorithm, grenade explosion method (GEM) and multi-objective genetic algorithm (MOGA). The results achieved by using self-adaptive Jaya algorithm are compared with those achieved by using the NPGA, RSM, LFOPC, TLBO, GEM and MOGA algorithms. The self-adaptive Jaya algorithm is proved superior as compared to the other optimization methods in terms of the results, computational effort and function evalutions.

  3. Transient thermal stresses in a transversely isotropic finite hollow circular cylinder due to arbitrary surface heat generations

    International Nuclear Information System (INIS)

    Sugano, Yoshihiro; Nakanishi, Takanori.

    1980-01-01

    The materials macroscopically regarded as anisotropic materials such as fiber-reinforced composite materials have become to be used for the structural elements at elevated temperature, and the studies on the problem of thermal stress in anisotropic bodies are carried out actively. The unsteady thermal stress in anisotropic finite circular cylinders has not been analyzed so far. In this study, the problem of unsteady thermal stress in an anisotropic finite circular cylinder having arbitrary surface heat generation in axial direction on the internal and external surfaces, and emitting heat from both ends and the internal and external surfaces, was analyzed. For the analysis of temperature distribution, generalized finite Fourier transformation and finite Hankel transformation were used, and thermal stress and thermal displacement were analyzed by the use of the stress function of Singh. By adopting the function used for the transformation nucleus in generalized finite Fourier transformation as the stress function, the analysis was made without separating symmetric and opposite symmetric problems. Numerical calculation was carried out on the basis of the analytical results, and the effects of the anisotropy in thermal conductivity, Young's modulus and linear expansion on unsteady temperature distribution, thermal stress and thermal displacement were quantitatively examined. (Kako, I.)

  4. Coping with temperature at the warm edge--patterns of thermal adaptation in the microbial eukaryote Paramecium caudatum.

    Directory of Open Access Journals (Sweden)

    Sascha Krenek

    Full Text Available Ectothermic organisms are thought to be severely affected by global warming since their physiological performance is directly dependent on temperature. Latitudinal and temporal variations in mean temperatures force ectotherms to adapt to these complex environmental conditions. Studies investigating current patterns of thermal adaptation among populations of different latitudes allow a prediction of the potential impact of prospective increases in environmental temperatures on their fitness.In this study, temperature reaction norms were ascertained among 18 genetically defined, natural clones of the microbial eukaryote Paramecium caudatum. These different clones have been isolated from 12 freshwater habitats along a latitudinal transect in Europe and from 3 tropical habitats (Indonesia. The sensitivity to increasing temperatures was estimated through the analysis of clone specific thermal tolerances and by relating those to current and predicted temperature data of their natural habitats. All investigated European clones seem to be thermal generalists with a broad thermal tolerance and similar optimum temperatures. The weak or missing co-variation of thermal tolerance with latitude does not imply local adaptation to thermal gradients; it rather suggests adaptive phenotypic plasticity among the whole European subpopulation. The tested Indonesian clones appear to be locally adapted to the less variable, tropical temperature regime and show higher tolerance limits, but lower tolerance breadths.Due to the lack of local temperature adaptation within the European subpopulation, P. caudatum genotypes at the most southern edge of their geographic range seem to suffer from the predicted increase in magnitude and frequency of summer heat waves caused by climate change.

  5. Transcriptomic and proteomic analysis of Oenococcus oeni adaptation to wine stress conditions

    Directory of Open Access Journals (Sweden)

    Mar Margalef-Català

    2016-09-01

    Full Text Available Oenococcus oeni, the main lactic acid bacteria responsible for malolactic fermentation in wine, has to adapt to stressful conditions, such as low pH and high ethanol content. In this study, the changes in the transcriptome and the proteome of O. oeni PSU-1 during the adaptation period before MLF start have been studied. DNA microarrays were used for the transcriptomic analysis and two complementary proteomic techniques, 2-D DIGE and iTRAQ labeling were used to analyze the proteomic response. One of the most influenced functions in PSU-1 due to inoculation into wine-like medium (WLM was translation, showing the over-expression of certain ribosomal genes and the corresponding proteins. Amino acid metabolism and transport was also altered and several peptidases were up regulated both at gene and protein level. Certain proteins involved in glutamine and glutamate metabolism showed an increased abundance revealing the key role of nitrogen uptake under stressful conditions. A strong transcriptional inhibition of carbohydrate metabolism related genes was observed. On the other hand, the transcriptional up-regulation of malate transport and citrate consumption was indicative of the use of L-malate and citrate associated to stress response and as an alternative energy source to sugar metabolism. Regarding the stress mechanisms, our results support the relevance of the thioredoxin and glutathione systems in the adaptation of O. oeni to wine related stress. Genes and proteins related to cell wall showed also significant changes indicating the relevance of the cell envelop as protective barrier to environmental stress. The differences found between transcriptomic and proteomic data suggested the relevance of post-transcriptional mechanisms and the complexity of the stress response in O. oeni adaptation. Further research should deepen into the metabolisms mostly altered due to wine conditions to elucidate the role of each mechanism in the O. oeni ability to

  6. Evolution and Adaptation of Wild Emmer Wheat Populations to Biotic and Abiotic Stresses.

    Science.gov (United States)

    Huang, Lin; Raats, Dina; Sela, Hanan; Klymiuk, Valentina; Lidzbarsky, Gabriel; Feng, Lihua; Krugman, Tamar; Fahima, Tzion

    2016-08-04

    The genetic bottlenecks associated with plant domestication and subsequent selection in man-made agroecosystems have limited the genetic diversity of modern crops and increased their vulnerability to environmental stresses. Wild emmer wheat, the tetraploid progenitor of domesticated wheat, distributed along a wide range of ecogeographical conditions in the Fertile Crescent, has valuable "left behind" adaptive diversity to multiple diseases and environmental stresses. The biotic and abiotic stress responses are conferred by series of genes and quantitative trait loci (QTLs) that control complex resistance pathways. The study of genetic diversity, genomic organization, expression profiles, protein structure and function of biotic and abiotic stress-resistance genes, and QTLs could shed light on the evolutionary history and adaptation mechanisms of wild emmer populations for their natural habitats. The continuous evolution and adaptation of wild emmer to the changing environment provide novel solutions that can contribute to safeguarding food for the rapidly growing human population.

  7. Low-stress photosensitive polyimide suspended membrane for improved thermal isolation performance

    Science.gov (United States)

    Fan, J.; Xing, R. Y.; Wu, W. J.; Liu, H. F.; Liu, J. Q.; Tu, L. C.

    2017-11-01

    In this paper, we introduce a method of isolating thermal conduction from silicon substrate for accommodating thermal-sensitive micro-devices. This method lies in fabrication of a low-stress photosensitive polyimide (PSPI) suspension structure which has lower thermal conductivity than silicon. First, a PSPI layer was patterned on a silicon wafer and hard baked. Then, a cavity was etched from the backside of the silicon substrate to form a membrane or a bridge-shape PSPI structure. After releasing, a slight deformation of about 20 nm was observed in the suspended structures, suggesting ultralow residual stress which is essential for accommodating micro-devices. In order to investigate the thermal isolation performance of the suspended PSPI structures, micro Pirani vacuum gauges, which are thermal-sensitive, had been fabricated on the PSPI structures. The measurement results illustrated that the Pirani gauges worked as expected in the range from 1- 470 Pa. Moreover, the results of the Pirani gauges based on the membrane and bridge structures were comparable, indicating that the commonly used bridge-shape structure for further reducing thermal conduction was unnecessary. Due to the excellent thermal isolation performance of PSPI, the suspended PSPI membrane is promising to be an outstanding candidate for thermal isolation applications.

  8. Stress and reliability analyses of multilayered composite cylinder under thermal and mechanical loads

    Science.gov (United States)

    Wang, Xiaohua

    The coupling resulting from the mutual influence of material thermal and mechanical parameters is examined in the thermal stress analysis of a multilayered isotropic composite cylinder subjected to sudden axisymmetric external and internal temperature. The method of complex frequency response functions together with the Fourier transform technique is utilized. Because the coupling parameters for some composite materials, such as carbon-carbon, are very small, the effect of coupling is neglected in the orthotropic thermal stress analysis. The stress distributions in multilayered orthotropic cylinders subjected to sudden axisymmetric temperature loading combined with dynamic pressure as well as asymmetric temperature loading are also obtained. The method of Fourier series together with the Laplace transform is utilized in solving the heat conduction equation and thermal stress analysis. For brittle materials, like carbon-carbon composites, the strength variability is represented by two or three parameter Weibull distributions. The 'weakest link' principle which takes into account both the carbon-carbon composite cylinders. The complex frequency response analysis is performed on a multilayered orthotropic cylinder under asymmetrical thermal load. Both deterministic and random thermal stress and reliability analyses can be based on the results of this frequency response analysis. The stress and displacement distributions and reliability of rocket motors under static or dynamic line loads are analyzed by an elasticity approach. Rocket motors are modeled as long hollow multilayered cylinders with an air core, a thick isotropic propellant inner layer and a thin orthotropic kevlar-epoxy case. The case is treated as a single orthotropic layer or a ten layered orthotropic structure. Five material properties and the load are treated as random variable with normal distributions when the reliability of the rocket motor is analyzed by the first-order, second-moment method (FOSM).

  9. Effects of thermal residual stresses and fiber packing on deformation of metal-matrix composites

    International Nuclear Information System (INIS)

    Nakamura, T.; Suresh, S.

    1993-01-01

    The combined effects of thermal residual stresses and fiber spatial distribution on the deformation of a 6061 aluminum alloy containing a fixed concentration unidirectional boron fibers have been analyzed using detailed finite element models. The geometrical structure includes perfectly periodic, uniformly space fiber arrangements in square and hexagonal cells, as well as different cells in which either 30 or 60 fibers are randomly placed in the ductile matrix. The model involves an elastic-plastic matrix, elastic fibers, and mechanically bonded interfaces. The results indicate that both fiber packing and thermal residual stresses can have a significant effect on the stress-strain characteristics of the composite. The thermal residual stresses cause pronounced matrix yielding which also influences the apparent overall stiffness of the composite during the initial stages of subsequent far-field loading along the axial and transverse direction. Furthermore, the thermal residual stresses apparently elevate the flow stress of the composite during transverse tension. Such effects can be traced back to the level of constraint imposed on the matrix by local fiber spacing. The implications of the present results to the processing of the composites are also briefly addressed

  10. Thermal adaptation and diversity in tropical ecosystems: evidence from cicadas (Hemiptera, Cicadidae.

    Directory of Open Access Journals (Sweden)

    Allen F Sanborn

    Full Text Available The latitudinal gradient in species diversity is a central problem in ecology. Expeditions covering approximately 16°54' of longitude and 21°4' of latitude and eight Argentine phytogeographic regions provided thermal adaptation data for 64 species of cicadas. We test whether species diversity relates to the diversity of thermal environments within a habitat. There are general patterns of the thermal response values decreasing in cooler floristic provinces and decreasing maximum potential temperature within a habitat except in tropical forest ecosystems. Vertical stratification of the plant communities leads to stratification in species using specific layers of the habitat. There is a decrease in thermal tolerances in species from the understory communities in comparison to middle level or canopy fauna. The understory Herrera umbraphila Sanborn & Heath is the first diurnally active cicada identified as a thermoconforming species. The body temperature for activity in H. umbraphila is less than and significantly different from active body temperatures of all other studied species regardless of habitat affiliation. These data suggest that variability in thermal niches within the heterogeneous plant community of the tropical forest environments permits species diversification as species adapt their physiology to function more efficiently at temperatures different from their potential competitors.

  11. Thermal adaptation and diversity in tropical ecosystems: evidence from cicadas (Hemiptera, Cicadidae).

    Science.gov (United States)

    Sanborn, Allen F; Heath, James E; Phillips, Polly K; Heath, Maxine S; Noriega, Fernando G

    2011-01-01

    The latitudinal gradient in species diversity is a central problem in ecology. Expeditions covering approximately 16°54' of longitude and 21°4' of latitude and eight Argentine phytogeographic regions provided thermal adaptation data for 64 species of cicadas. We test whether species diversity relates to the diversity of thermal environments within a habitat. There are general patterns of the thermal response values decreasing in cooler floristic provinces and decreasing maximum potential temperature within a habitat except in tropical forest ecosystems. Vertical stratification of the plant communities leads to stratification in species using specific layers of the habitat. There is a decrease in thermal tolerances in species from the understory communities in comparison to middle level or canopy fauna. The understory Herrera umbraphila Sanborn & Heath is the first diurnally active cicada identified as a thermoconforming species. The body temperature for activity in H. umbraphila is less than and significantly different from active body temperatures of all other studied species regardless of habitat affiliation. These data suggest that variability in thermal niches within the heterogeneous plant community of the tropical forest environments permits species diversification as species adapt their physiology to function more efficiently at temperatures different from their potential competitors.

  12. Experiments and analysis of thermal stresses around the nozzle of the reactor vessel

    International Nuclear Information System (INIS)

    Song, D.H.; Oh, J.H.; Song, H.K.; Park, D.S.; Shon, K.H.

    1981-01-01

    This report describes the results of analysis and experiments on the thermal stress around the reactor vessel nozzle performed to establish a capability of thermal stress analysis of pressure vessel subjected to thermal loadings. Firstly, heat conduction analysis during reactor design transients and analysis on the experimental model were performed using computer code FETEM-1 for the purpose of verification of FETEM-1 which was developed in 1979 and will be used to obtain the temperature distribution in a solid body under the steady-state and the transient conditions. The results of the analysis was compared to the results in the Stress Report of Kori-1 reactor vessel and those from experiments on the model, respectively

  13. Modelling and analysis of radial thermal stresses and temperature ...

    African Journals Online (AJOL)

    user

    The temperature field, heat transfer rate and thermal stresses were investigated with numerical simulation models using FORTRAN FE (finite element) software. ...... specific heats, International Communications in Heat and Mass Transfer, Vol.

  14. Residual stress determination in thermally sprayed metallic deposits by neutron diffraction

    International Nuclear Information System (INIS)

    Keller, Thomas; Margadant, Nikolaus; Pirling, Thilo; Riegert-Escribano, Maria J.; Wagner, Werner

    2004-01-01

    Neutron diffraction was used to obtain spatially resolved strain and stress profiles in thermally sprayed metallic 'NiCrAlY' deposits (chemical composition 67 wt.% Ni, 22 wt.% Cr, 10 wt.% Al, 1 wt.% Y) and the underlying steel substrates. Samples of four different spray techniques were analyzed: atmospheric and water stabilized plasma spraying (APS and WSP), flame spraying (FS) and wire arc spraying (WAS). The results are quantitatively compared with the average in-plane residual stress determined by complementary bending tests and the hole drilling technique. While the stress profiles from the surface to the interface in the deposits are similar for all investigated spray techniques, their absolute values and gradients vary strongly. This is attributed to different quenching stresses from the impinging particles, different thermal histories the deposit/substrate systems undergo during the spraying and subsequent cooling, and also to different coating properties. In the water stabilized plasma sprayed and the wire arc sprayed deposits, a gradient in the stress-free lattice parameter was observed. Crack formation is found to be a dominant mechanism for stress relaxation in the surface plane

  15. Thermal-stress analysis and testing of DIII-D armor tiles

    International Nuclear Information System (INIS)

    Baxi, C.B.; Anderson, P.M.; Reis, E.E.; Smith, J.P.; Smith, P.D.; Croesmann, C.; Watkins, J.; Whitley, J.

    1987-10-01

    It is planned to install about 1500 new armor tiles in the DIII-D tokamak. The armor tiles currently installed in DIII-D are made by brazing Poco AXF-5Q graphite onto Inconel X-750 stock. A small percentage of these have failed by breakage of graphite. These failures were believed to be related to significant residual stress remaining in graphite after brazing. Hence, an effort was undertaken to improve the design with all-graphite tiles. Three criteria must be satisfied by the armor tiles and the hardware used to attach the tiles to the vessel walls: tiles should not structurally fail, peak tile temperature must be less than 2500 K, and peak vessel stresses must be below acceptable levels. A number of alternate design concepts were first analyzed with the two-dimensional finite element codes TOPAZ2D and NIKE2D. Promising designs were optimized for best parameters such as thicknesses, etc. The two best designs were further analyzed for thermal stresses with the three-dimensional codes P/THERMAL and P/STRESS. Prototype tiles of a number of materials were fabricated by GA and tested at the Plasma Materials Test Facility of the Sandia National Laboratory at Albuquerque. The tests simulated the heat flux and cooling conditions in DIII-D. This paper describes the 2-D and 3-D thermal stress analyses, the test results and logic which led to the selected design of the DIII-D armor tiles. 5 refs., 7 figs., 3 tabs

  16. Photothermoelastic investigation of transient thermal stresses in circular plates with a hole heated by fluid

    International Nuclear Information System (INIS)

    Tsuji, Masatoshi; Tsujimura, Soichi; Oda, Masanobu.

    1980-01-01

    In this study, the practical use of the method of measuring the unsteady thermal stress in a body subjected to the thermal load due to fluid by photoelastic method and the improvement of accuracy were attempted. The internal wall of a hollow disk was heated with high temperature fluid, and the external wall was cooled with low temperature fluid or thermally insulated. The photoelastic experiment on this hollow disk was carried out in a vacuum tank to given axisymmetric temperature distribution and to prevent heat dissipation due to the convection from both surfaces of the disk, and the temperature distribution and thermal stress were measured. The experimental values were compared with the theoretical values, and the accuracy of the experimental method and measurement was examined. Moreover, the disk with an eccentric hole was tested by the same method, and the effects of the eccentricity and hole diameter on the maximum thermal stress were examined. The experimental apparatus and method, and the experimental results are described. By this method, the condition of thermal loading with fluid was almost attained, and the experimental values of unsteady thermal stress were in good agreement with the theoretical values. (Kako, I.)

  17. Response of coral assemblages to thermal stress: are bleaching intensity and spatial patterns consistent between events?

    Science.gov (United States)

    Penin, Lucie; Vidal-Dupiol, Jeremie; Adjeroud, Mehdi

    2013-06-01

    Mass bleaching events resulting in coral mortality are among the greatest threats to coral reefs, and are projected to increase in frequency and intensity with global warming. Achieving a better understanding of the consistency of the response of coral assemblages to thermal stress, both spatially and temporally, is essential to determine which reefs are more able to tolerate climate change. We compared variations in spatial and taxonomic patterns between two bleaching events at the scale of an island (Moorea Island, French Polynesia). Despite similar thermal stress and light conditions, bleaching intensity was significantly lower in 2007 (approximately 37 % of colonies showed signs of bleaching) than in 2002, when 55 % of the colonies bleached. Variations in the spatial patterns of bleaching intensity were consistent between the two events. Among nine sampling stations at three locations and three depths, the stations at which the bleaching response was lowest in 2002 were those that showed the lowest levels of bleaching in 2007. The taxonomic patterns of susceptibility to bleaching were also consistent between the two events. These findings have important implications for conservation because they indicate that corals are capable of acclimatization and/or adaptation and that, even at small spatial scales, some areas are consistently more susceptible to bleaching than others.

  18. Genotypic variation influences reproductive success and thermal stress tolerance in the reef building coral, Acropora palmata

    Science.gov (United States)

    Baums, I. B.; Devlin-Durante, M. K.; Polato, N. R.; Xu, D.; Giri, S.; Altman, N. S.; Ruiz, D.; Parkinson, J. E.; Boulay, J. N.

    2013-09-01

    The branching coral Acropora palmata is a foundation species of Caribbean reefs that has been decimated in recent decades by anthropogenic and natural stressors. Declines in population density and genotypic diversity likely reduce successful sexual reproduction in this self-incompatible hermaphrodite and might impede recovery. We investigated variation among genotypes in larval development under thermally stressful conditions. Six two-parent crosses and three four-parent batches were reared under three temperatures and sampled over time. Fertilization rates differed widely with two-parent crosses having lower fertilization rates (5-56 %, mean 22 % ± 22 SD) than batches (from 31 to 87 %, mean 59 % ± 28 SD). Parentage analysis of larvae in batch cultures showed differences in gamete compatibility among parents, coinciding with significant variation in both sperm morphology and egg size. While all larval batches developed more rapidly at increased water temperatures, rate of progression through developmental stages varied among batches, as did swimming speed. Together, these results indicate that loss of genotypic diversity exacerbates already severe limitations in sexual reproductive success of A. palmata. Nevertheless, surviving parental genotypes produce larvae that do vary in their phenotypic response to thermal stress, with implications for adaptation, larval dispersal and population connectivity in the face of warming sea surface temperatures.

  19. Thermal and stress analyses in thermoelectric generator with tapered and rectangular pin configurations

    International Nuclear Information System (INIS)

    Yilbas, Bekir Sami; Akhtar, S.S.; Sahin, A.Z.

    2016-01-01

    Thermal stress developed in thermoelectric generators is critical for long service applications. High temperature gradients, due to a large temperature difference across the junctions, causes excessive stress levels developed in the device pins and electrodes at the interfaces. In the present study, a thermoelectric generator with horizontal pin configuration is considered and thermal stress analysis in the device is presented. Ceramic wafer is considered to resemble the high temperature plate and copper electrodes are introduced at the pin junctions to reduce the electrical resistance between the pins and the high and low temperature junction plates during the operation. Finite element code is used to simulate temperature and stress fields in the thermoelectric generator. In the simulations, convection and radiation losses from the thermoelectric pins are considered and bismuth telluride pin material with and without tapering is incorporated. It is found that von Mises stress attains high values at the interface between the hot and cold junctions and the copper electrodes. Thermal stress developed in tapered pin configuration attains lower values than that of rectangular pin cross-section. - Highlights: • Different cold junction temperatures improves thermoelectric generator performance. • von Mises stress remains high across copper electrodes and hot junction ceramics. • von Mises stress reduces along pin length towards cold junction. • Pin tapering lowers stress levels in thermoelectric generator.

  20. Thermal Stress of Surface of Mold Cavities and Parting Line of Silicone Molds

    Directory of Open Access Journals (Sweden)

    Bajčičák Martin

    2014-06-01

    Full Text Available The paper is focused on the study of thermal stress of surface of mold cavities and parting line of silicone molds after pouring. The silicone mold White SD - THT was thermally stressed by pouring of ZnAl4Cu3 zinc alloy with pouring cycle 20, 30 and 40 seconds. The most thermally stressed part of surface at each pouring cycle is gating system and mold cavities. It could be further concluded that linear increase of the pouring cycle time leads to the exponential increasing of the maximum temperature of mold surface after its cooling. The elongated pouring cycle increases the temperature accumulated on the surface of cavities and the ability of silicone mold to conduct the heat on its surface decreases, because the low thermal conductivity of silicone molds enables the conduction of larger amount of heat into ambient environment.

  1. Adaptive stress response to menadione-induced oxidative stress in Saccharomyces cerevisiae KNU5377.

    Science.gov (United States)

    Kim, Il-Sup; Sohn, Ho-Yong; Jin, Ingnyol

    2011-10-01

    The molecular mechanisms involved in the ability of yeast cells to adapt and respond to oxidative stress are of great interest to the pharmaceutical, medical, food, and fermentation industries. In this study, we investigated the time-dependent, cellular redox homeostasis ability to adapt to menadione-induced oxidative stress, using biochemical and proteomic approaches in Saccharomyces cerevisiae KNU5377. Time-dependent cell viability was inversely proportional to endogenous amounts of ROS measured by a fluorescence assay with 2',7'-dichlorofluorescin diacetate (DCFHDA), and was hypersensitive when cells were exposed to the compound for 60 min. Morphological changes, protein oxidation and lipid peroxidation were also observed. To overcome the unfavorable conditions due to the presence of menadione, yeast cells activated a variety of cell rescue proteins including antioxidant enzymes, molecular chaperones, energy-generating metabolic enzymes, and antioxidant molecules such as trehalose. Thus, these results show that menadione causes ROS generation and high accumulation of cellular ROS levels, which affects cell viability and cell morphology and there is a correlation between resistance to menadione and the high induction of cell rescue proteins after cells enter into this physiological state, which provides a clue about the complex and dynamic stress response in yeast cells.

  2. Thermal stresses in rectangular plates: variational and finite element solutions

    International Nuclear Information System (INIS)

    Laura, P.A.A.; Gutierrez, R.H.; Sanchez Sarmiento, G.; Basombrio, F.G.

    1978-01-01

    This paper deals with the development of an approximate method for the analysis of thermal stresses in rectangular plates (plane stress problem) and an evaluation of the relative accuracy of the finite element method. The stress function is expanded in terms of polynomial coordinate functions which identically satisfy the boundary conditions, and a variational approach is used to determine the expansion coefficients. The results are in good agreement with a finite element approach. (Auth.)

  3. A plant microRNA regulates the adaptation of roots to drought stress

    KAUST Repository

    Chen, Hao; Li, Zhuofu; Xiong, Liming

    2012-01-01

    Plants tend to restrict their horizontal root proliferation in response to drought stress, an adaptive response mediated by the phytohormone abscisic acid (ABA) in antagonism with auxin through unknown mechanisms. Here, we found that stress

  4. Heat stress and dehydration in adapting for performance: Good, bad, both, or neither?

    Science.gov (United States)

    Akerman, Ashley Paul; Tipton, Michael; Minson, Christopher T; Cotter, James David

    2016-01-01

    Physiological systems respond acutely to stress to minimize homeostatic disturbance, and typically adapt to chronic stress to enhance tolerance to that or a related stressor. It is legitimate to ask whether dehydration is a valuable stressor in stimulating adaptation per se . While hypoxia has had long-standing interest by athletes and researchers as an ergogenic aid, heat and nutritional stressors have had little interest until the past decade. Heat and dehydration are highly interlinked in their causation and the physiological strain they induce, so their individual roles in adaptation are difficult to delineate. The effectiveness of heat acclimation as an ergogenic aid remains unclear for team sport and endurance athletes despite several recent studies on this topic. Very few studies have examined the potential ergogenic (or ergolytic) adaptations to ecologically-valid dehydration as a stressor in its own right, despite longstanding evidence of relevant fluid-regulatory adaptations from short-term hypohydration. Transient and self-limiting dehydration (e.g., as constrained by thirst), as with most forms of stress, might have a time and a place in physiological or behavioral adaptations independently or by exacerbating other stressors (esp. heat); it cannot be dismissed without the appropriate evidence. The present review did not identify such evidence. Future research should identify how the magnitude and timing of dehydration might augment or interfere with the adaptive processes in behaviorally constrained versus unconstrained humans.

  5. Effects of Yoga on Stress, Stress Adaption, and Heart Rate Variability Among Mental Health Professionals--A Randomized Controlled Trial.

    Science.gov (United States)

    Lin, Shu-Ling; Huang, Ching-Ya; Shiu, Shau-Ping; Yeh, Shu-Hui

    2015-08-01

    Mental health professionals experiencing work-related stress may experience burn out, leading to a negative impact on their organization and patients. The aim of this study was to examine the effects of yoga classes on work-related stress, stress adaptation, and autonomic nerve activity among mental health professionals. A randomized controlled trial was used, which compared the outcomes between the experimental (e.g., yoga program) and the control groups (e.g., no yoga exercise) for 12 weeks. Work-related stress and stress adaptation were assessed before and after the program. Heart rate variability (HRV) was measured at baseline, midpoint through the weekly yoga classes (6 weeks), and postintervention (after 12 weeks of yoga classes). The results showed that the mental health professionals in the yoga group experienced a significant reduction in work-related stress (t = -6.225, p control group revealed no significant changes. Comparing the mean differences in pre- and posttest scores between yoga and control groups, we found the yoga group significantly decreased work-related stress (t = -3.216, p = .002), but there was no significant change in stress adaptation (p = .084). While controlling for the pretest scores of work-related stress, participants in yoga, but not the control group, revealed a significant increase in autonomic nerve activity at midpoint (6 weeks) test (t = -2.799, p = .007), and at posttest (12 weeks; t = -2.099, p = .040). Because mental health professionals experienced a reduction in work-related stress and an increase in autonomic nerve activity in a weekly yoga program for 12 weeks, clinicians, administrators, and educators should offer yoga classes as a strategy to help health professionals reduce their work-related stress and balance autonomic nerve activities. © 2015 The Authors. Worldviews on Evidence-Based Nursing published by Wiley Periodicals, Inc. on behalf of Society for Worldviews on Evidence-Based Nursing.

  6. Differential gene expression during thermal stress and bleaching in the Caribbean coral Montastraea faveolata.

    Science.gov (United States)

    DeSalvo, M K; Voolstra, C R; Sunagawa, S; Schwarz, J A; Stillman, J H; Coffroth, M A; Szmant, A M; Medina, M

    2008-09-01

    The declining health of coral reefs worldwide is likely to intensify in response to continued anthropogenic disturbance from coastal development, pollution, and climate change. In response to these stresses, reef-building corals may exhibit bleaching, which marks the breakdown in symbiosis between coral and zooxanthellae. Mass coral bleaching due to elevated water temperature can devastate coral reefs on a large geographical scale. In order to understand the molecular and cellular basis of bleaching in corals, we have measured gene expression changes associated with thermal stress and bleaching using a complementary DNA microarray containing 1310 genes of the Caribbean coral Montastraea faveolata. In a first experiment, we identified differentially expressed genes by comparing experimentally bleached M. faveolata fragments to control non-heat-stressed fragments. In a second experiment, we identified differentially expressed genes during a time course experiment with four time points across 9 days. Results suggest that thermal stress and bleaching in M. faveolata affect the following processes: oxidative stress, Ca(2+) homeostasis, cytoskeletal organization, cell death, calcification, metabolism, protein synthesis, heat shock protein activity, and transposon activity. These results represent the first medium-scale transcriptomic study focused on revealing the cellular foundation of thermal stress-induced coral bleaching. We postulate that oxidative stress in thermal-stressed corals causes a disruption of Ca(2+) homeostasis, which in turn leads to cytoskeletal and cell adhesion changes, decreased calcification, and the initiation of cell death via apoptosis and necrosis.

  7. Three dimensional, thermal stress analysis of a welded plate

    International Nuclear Information System (INIS)

    Koening, H.A.; Lai, C.K.-F.; Morral, J.E.

    1985-01-01

    A general finite element thermal stress analysis has been developed. The analysis can be uncoupled to solve either the heat transfer problem or the stress problem independently and it can accommodate non-linear material behavior, initial states of stress and strain, and moving boundary conditions. A unique feature of the model it that it properly accounts for the latent heat effect during phase changes. Applying the moving heat flux boundary condition to simulate arc welding, the model has been used to predict the transient thermal mechanical response of a welded plate. It is the absorption and liberation of latent heat in the fusion zone of a weld which complicates numerical methods of treating welding. For pure materials and eutectic alloys the latent heat effect is less of a problem because phase changes take place at a specific temperature. But for most alloys, phase changes take place over a range of temperatures bounded by the solidus, T S , and liquidus, T L , and the latent heat effect occurs continuously over the temperature range. (author)

  8. [Improvement of thermal adaptability and fermentation of industrial ethanologenic yeast by genomic DNA mutagenesis-based genetic recombination].

    Science.gov (United States)

    Liu, Xiuying; He, Xiuping; Lu, Ying; Zhang, Borun

    2011-07-01

    Ethanol is an attractive alternative to fossil fuels. Saccharomyces cerevisiae is the most important ethanol producer. However, in the process of industrial production of ethanol, both cell growth and fermentation of ethanologenic S. cerevisiae are dramatically affected by environmental stresses, such as thermal stress. In this study, we improved both the thermotolerance and fermentation performance of industrial ethanologenic S. cerevisiae by combined usage of chemical mutagenesis and genomic DNA mutagenesis-based genetic recombination method. The recombinant S. cerevisiae strain T44-2 could grow at 44 degrees C, 3 degrees C higher than that of the original strain CE6. The survival rate of T44-2 was 1.84 and 1.87-fold of that of CE6 when heat shock at 48 degrees C and 52 degrees C for 1 h respectively. At temperature higher than 37 degrees C, recombinant strain T44-2 always gave higher cell growth and ethanol production than those of strain CE6. Meanwhile, from 30 degrees C to 40 degrees C, recombinant strain T44-2 produces 91.2-83.8 g/L of ethanol from 200 g/L of glucose, which indicated that the recombinant strain T44-2 had both thermotolerance and broad thermal adaptability. The work offers a novel method, called genomic DNA mutagenesis-based genetic recombination, to improve the physiological functions of S. cerevisiae.

  9. A self-adaptive thermal switch array for rapid temperature stabilization under various thermal power inputs

    International Nuclear Information System (INIS)

    Geng, Xiaobao; Patel, Pragnesh; Narain, Amitabh; Meng, Dennis Desheng

    2011-01-01

    A self-adaptive thermal switch array (TSA) based on actuation by low-melting-point alloy droplets is reported to stabilize the temperature of a heat-generating microelectromechanical system (MEMS) device at a predetermined range (i.e. the optimal working temperature of the device) with neither a control circuit nor electrical power consumption. When the temperature is below this range, the TSA stays off and works as a thermal insulator. Therefore, the MEMS device can quickly heat itself up to its optimal working temperature during startup. Once this temperature is reached, TSA is automatically turned on to increase the thermal conductance, working as an effective thermal spreader. As a result, the MEMS device tends to stay at its optimal working temperature without complex thermal management components and the associated parasitic power loss. A prototype TSA was fabricated and characterized to prove the concept. The stabilization temperatures under various power inputs have been studied both experimentally and theoretically. Under the increment of power input from 3.8 to 5.8 W, the temperature of the device increased only by 2.5 °C due to the stabilization effect of TSA

  10. Rotational Kinematics Model Based Adaptive Particle Filter for Robust Human Tracking in Thermal Omnidirectional Vision

    Directory of Open Access Journals (Sweden)

    Yazhe Tang

    2015-01-01

    Full Text Available This paper presents a novel surveillance system named thermal omnidirectional vision (TOV system which can work in total darkness with a wild field of view. Different to the conventional thermal vision sensor, the proposed vision system exhibits serious nonlinear distortion due to the effect of the quadratic mirror. To effectively model the inherent distortion of omnidirectional vision, an equivalent sphere projection is employed to adaptively calculate parameterized distorted neighborhood of an object in the image plane. With the equivalent projection based adaptive neighborhood calculation, a distortion-invariant gradient coding feature is proposed for thermal catadioptric vision. For robust tracking purpose, a rotational kinematic modeled adaptive particle filter is proposed based on the characteristic of omnidirectional vision, which can handle multiple movements effectively, including the rapid motions. Finally, the experiments are given to verify the performance of the proposed algorithm for human tracking in TOV system.

  11. Analysis of Acculturative Stress and Sociocultural Adaptation among International Students at a Non-Metropolitan University

    Science.gov (United States)

    Mahmood, Hajara; Burke, Monica Galloway

    2018-01-01

    This quantitative descriptive study analyzed levels of acculturative stress and sociocultural adaptation among international students at a non-metropolitan university in the United States related to certain demographic characteristics. Surveys were used to measure international students' levels of acculturative stress and sociocultural adaptation,…

  12. Radio-adaptive response

    International Nuclear Information System (INIS)

    Ikushima, T.

    1992-01-01

    An adaptive response to radiation stress was found as a suppressed induction of chromosomal damage including micronuclei and sister chromatid exchanges in cultured Chinese hamster V79 cells pre-exposed to very low doses of ionizing radiations. The mechanism underlying this novel chromosomal response, called 'radio-adaptive response (RAR)' has been studied progressively. The following results were obtained in recent experiments. 1. Low doses of β-rays from tritiated water (HTO) as well as tritium-thymidine can cause RAR. 2. Thermal neutrons, a high LET radiation, can not act as tritium β-rays or γ-rays. 3. The RAR expression is suppressed not only by the treatment with an inhibitor of protein synthesis but also by RNA synthesis inhibition. 4. Several proteins are newly synthesized concurrently with the RAR expression after the adapting doses, viewed by two-dimensional electrophoresis of cellular proteins. These results suggests that the RAR might be a cellular stress response to a signal produced preferentially by very low doses of low LET radiation under restricted conditions, accompany the inducible specific gene expression. (author)

  13. Thermal stress in the edge cladding of Nova glass laser disks

    International Nuclear Information System (INIS)

    Pitts, J.H.; Kong, M.K.; Gerhard, M.A.

    1987-01-01

    We calculated thermal stresses in Nova glass laser disks having light-absorbing edge cladding glass attached to the periphery with an epoxy adhesive. Our closed-form solutions indicated that, because the epoxy adhesive is only 25 μm across, it does not significantly affect the thermal stress in the disk or cladding glass. Our numerical results showed a peak tensile stress in the cladding glass of 24 MPa when the cladding glass had a uniform absorption coefficient of 7.5 cm -1 . This peak value is reduced to 19 MPa if surface parasitic oscillation heating is eliminated by tilting the disk edges. The peak tensile stresses exceed the typical 7 to 14-MPa working stress for glass; however, we have not observed any disk or cladding glass failures at peak Nova fluences of 20 J/cm 2 . We have observed delamination of the epoxy adhesive bond at fluences several times that which would occur on Nova. Replacement laser disks will incorporate cladding with a reduced absorption coefficient of 4.5 cm -1 . Recent experiments show that this reduced absorption coefficient is satisfactory

  14. Adaptive radiation along a thermal gradient: preliminary results of habitat use and respiration rate divergence among whitefish morphs.

    Directory of Open Access Journals (Sweden)

    Kimmo Kalevi Kahilainen

    Full Text Available Adaptive radiation is considered an important mechanism for the development of new species, but very little is known about the role of thermal adaptation during this process. Such adaptation should be especially important in poikilothermic animals that are often subjected to pronounced seasonal temperature variation that directly affects metabolic function. We conducted a preliminary study of individual lifetime thermal habitat use and respiration rates of four whitefish (Coregonus lavaretus (L. morphs (two pelagic, one littoral and one profundal using stable carbon and oxygen isotope values of otolith carbonate. These morphs, two of which utilized pelagic habitats, one littoral and one profundal recently diverged via adaptive radiation to exploit different major niches in a deep and thermally stratified subarctic lake. We found evidence that the morphs used different thermal niches. The profundal morph had the most distinct thermal niche and consistently occupied the coldest thermal habitat of the lake, whereas differences were less pronounced among the shallow water pelagic and littoral morphs. Our results indicated ontogenetic shifts in thermal niches: juveniles of all whitefish morphs inhabited warmer ambient temperatures than adults. According to sampling of the otolith nucleus, hatching temperatures were higher for benthic compared to pelagic morphs. Estimated respiration rate was the lowest for benthivorous profundal morph, contrasting with the higher values estimated for the other morphs that inhabited shallower and warmer water. These preliminary results suggest that physiological adaptation to different thermal habitats shown by the sympatric morphs may play a significant role in maintaining or strengthening niche segregation and divergence in life-history traits, potentially contributing to reproductive isolation and incipient speciation.

  15. Residual stress determination in thermally sprayed metallic deposits by neutron diffraction

    Energy Technology Data Exchange (ETDEWEB)

    Keller, Thomas; Margadant, Nikolaus; Pirling, Thilo; Riegert-Escribano, Maria J.; Wagner, Werner

    2004-05-25

    Neutron diffraction was used to obtain spatially resolved strain and stress profiles in thermally sprayed metallic 'NiCrAlY' deposits (chemical composition 67 wt.% Ni, 22 wt.% Cr, 10 wt.% Al, 1 wt.% Y) and the underlying steel substrates. Samples of four different spray techniques were analyzed: atmospheric and water stabilized plasma spraying (APS and WSP), flame spraying (FS) and wire arc spraying (WAS). The results are quantitatively compared with the average in-plane residual stress determined by complementary bending tests and the hole drilling technique. While the stress profiles from the surface to the interface in the deposits are similar for all investigated spray techniques, their absolute values and gradients vary strongly. This is attributed to different quenching stresses from the impinging particles, different thermal histories the deposit/substrate systems undergo during the spraying and subsequent cooling, and also to different coating properties. In the water stabilized plasma sprayed and the wire arc sprayed deposits, a gradient in the stress-free lattice parameter was observed. Crack formation is found to be a dominant mechanism for stress relaxation in the surface plane.

  16. Thermal stress analysis of the SLAC moveable mask. Addendum 2

    International Nuclear Information System (INIS)

    Johnson, G.L.

    1985-01-01

    X-ray beams emerging from the new SLAC electron-positron storage ring (PEP) can impinge on the walls of tangential divertor channels. A moveable mask made of 6061-T6 aluminum is installed in the channel to limit wall heating. The mask is cooled with water flowing axially at 30 0 C. Beam strikes on the mask cause highly localized heating in the channel structure. Analyses were completed to determine the temperatures and thermally-induced stresses due to this heating. The current design and operating conditions should result in the entrance to the moveable mask operating at a peak temperature of 88 0 C with a peak thermal stress at 19% of the yield of 6061-T6 aluminum

  17. Finite element analysis of thermal stress distribution in different ...

    African Journals Online (AJOL)

    Nigerian Journal of Clinical Practice • Jan-Feb 2016 • Vol 19 • Issue 1. Abstract ... Key words: Amalgam, finite element method, glass ionomer cement, resin composite, thermal stress ... applications for force analysis and assessment of different.

  18. Regulation of apoptotic pathways by Stylophora pistillata (Anthozoa, Pocilloporidae to survive thermal stress and bleaching.

    Directory of Open Access Journals (Sweden)

    Hagit Kvitt

    Full Text Available Elevated seawater temperatures are associated with coral bleaching events and related mortality. Nevertheless, some coral species are able to survive bleaching and recover. The apoptotic responses associated to this ability were studied over 3 years in the coral Stylophora pistillata from the Gulf of Eilat subjected to long term thermal stress. These include caspase activity and the expression profiles of the S. pistillata caspase and Bcl-2 genes (StyCasp and StyBcl-2-like cloned in this study. In corals exposed to thermal stress (32 or 34°C, caspase activity and the expression levels of the StyBcl-2-like gene increased over time (6-48 h and declined to basal levels within 72 h of thermal stress. Distinct transcript levels were obtained for the StyCasp gene, with stimulated expression from 6 to 48 h of 34°C thermal stress, coinciding with the onset of bleaching. Increased cell death was detected in situ only between 6 to 48 h of stress and was limited to the gastroderm. The bleached corals survived up to one month at 32°C, and recovered back symbionts when placed at 24°C. These results point to a two-stage response in corals that withstand thermal stress: (i the onset of apoptosis, accompanied by rapid activation of anti-oxidant/anti-apoptotic mediators that block the progression of apoptosis to other cells and (ii acclimatization of the coral to the chronic thermal stress alongside the completion of symbiosis breakdown. Accordingly, the coral's ability to rapidly curb apoptosis appears to be the most important trait affecting the coral's thermotolerance and survival.

  19. Thermal stress resistance of ion implanted sapphire crystals

    International Nuclear Information System (INIS)

    Gurarie, V.N.; Jamieson, D.N.; Szymanski, R.; Orlov, A.V.; Williams, J.S.; Conway, M.

    1999-01-01

    Monocrystals of sapphire have been subjected to ion implantation with 86 keV Si - and 80 keV Cr - ions to doses in the range of 5x10 14 -5x10 16 cm -2 prior to thermal stress testing in a pulsed plasma. Above a certain critical dose ion implantation is shown to modify the near-surface structure of samples by introducing damage, which makes crack nucleation easier under the applied stress. The effect of ion dose on the stress resistance is investigated and the critical doses which produce a noticeable change in the stress resistance are determined. The critical dose for Si ions is shown to be much lower than that for Cr - ions. However, for doses exceeding 2x10 16 cm -2 the stress resistance parameter decreases to approximately the same value for both implants. The size of the implantation-induced crack nucleating centers and the density of the implantation-induced defects are considered to be the major factors determining the stress resistance of sapphire crystals irradiated with Si - and Cr - ions

  20. Two-dimensional simulation of the thermal stress effect on static and dynamic VDMOS characteristics

    International Nuclear Information System (INIS)

    Alwan, M.; Beydoun, B.; Ketata, K.; Zoaeter, M.

    2005-01-01

    Using a two-dimensional simulator, the effect of the thermal stress on static and dynamic vertical double-diffusion metal oxide semiconductor (VDMOS) characteristics have been investigated. The use of the device under certain thermal stress conditions can produce modifications of its physical and electrical properties. Based on physics and 2D simulations, this paper proposes an analysis of this stress effect observed on the electrical characteristics of the device. Parameters responsible of these modifications are determined. Approximate expressions of the ionization coefficients and breakdown voltage in terms of temperature are proposed. Non-punch-through junction theory is used to express the breakdown voltage and the space charge extension with respect to the impurity concentration and the temperature. The capacitances of the device have been also studied. The effect of the stress on C-V characteristics is observed and analyzed. We notice that the drain-gate, drain-source and gate-source capacitances are shifted due to the degradation of device physical properties versus thermal stress

  1. Influence of solder joint length to the mechanical aspect during the thermal stress analysis

    Science.gov (United States)

    Tan, J. S.; Khor, C. Y.; Rahim, Wan Mohd Faizal Wan Abd; Ishak, Muhammad Ikman; Rosli, M. U.; Jamalludin, Mohd Riduan; Zakaria, M. S.; Nawi, M. A. M.; Aziz, M. S. Abdul; Ani, F. Che

    2017-09-01

    Solder joint is an important interconnector in surface mount technology (SMT) assembly process. The real time stress, strain and displacement of the solder joint is difficult to observe and assess the experiment. To tackle these problems, simulation analysis was employed to study the von Mises stress, strain and displacement in the thermal stress analysis by using Finite element based software. In this study, a model of leadless electronic package was considered. The thermal stress analysis was performed to investigate the effect of the solder length to those mechanical aspects. The simulation results revealed that solder length gives significant effect to the maximum von Mises stress to the solder joint. Besides, changes in solder length also influence the displacement of the solder joint in the thermal environment. The increment of the solder length significantly reduces the von Mises stress and strain on the solder joint. Thus, the understanding of the physical parameter for solder joint is important for engineer prior to designing the solder joint of the electronic component.

  2. Susceptibility to a metal under global warming is shaped by thermal adaptation along a latitudinal gradient.

    Science.gov (United States)

    Dinh Van, Khuong; Janssens, Lizanne; Debecker, Sara; De Jonge, Maarten; Lambret, Philippe; Nilsson-Örtman, Viktor; Bervoets, Lieven; Stoks, Robby

    2013-09-01

    Global warming and contamination represent two major threats to biodiversity that have the potential to interact synergistically. There is the potential for gradual local thermal adaptation and dispersal to higher latitudes to mitigate the susceptibility of organisms to contaminants and global warming at high latitudes. Here, we applied a space-for-time substitution approach to study the thermal dependence of the susceptibility of Ischnura elegans damselfly larvae to zinc in a common garden warming experiment (20 and 24 °C) with replicated populations from three latitudes spanning >1500 km in Europe. We observed a striking latitude-specific effect of temperature on the zinc-induced mortality pattern; local thermal adaptation along the latitudinal gradient made Swedish, but not French, damselfly larvae more susceptible to zinc at 24 °C. Latitude- and temperature-specific differences in zinc susceptibility may be related to the amount of energy available to defend against and repair damage since Swedish larvae showed a much stronger zinc-induced reduction of food intake at 24 °C. The pattern of local thermal adaptation indicates that the predicted temperature increase of 4 °C by 2100 will strongly magnify the impact of a contaminant such as zinc at higher latitudes unless there is thermal evolution and/or migration of lower latitude genotypes. Our results underscore the critical importance of studying the susceptibility to contaminants under realistic warming scenarios taking into account local thermal adaptation across natural temperature gradients. © 2013 John Wiley & Sons Ltd.

  3. Transcriptome analysis and identification of significantly differentially expressed genes in Holstein calves subjected to severe thermal stress

    Science.gov (United States)

    Srikanth, Krishnamoorthy; Lee, Eunjin; Kwan, Anam; Lim, Youngjo; Lee, Junyep; Jang, Gulwon; Chung, Hoyoung

    2017-11-01

    RNA-Seq analysis was used to characterize transcriptome response of Holstein calves to thermal stress. A total of eight animals aged between 2 and 3 months were randomly selected and subjected to thermal stress corresponding to a temperature humidity index of 95 in an environmentally controlled house for 12 h consecutively for 3 days. A set of 15,787 unigenes were found to be expressed and after a threshold of threefold change, and a Q value physiological and metabolic processes to survive. Many of the genes identified in this study have not been previously reported to be involved in thermal stress response. The results of this study extend our understanding of the animal's response to thermal stress and some of the identified genes may prove useful in the efforts to breed Holstein cattle with superior thermotolerance, which might help in minimizing production loss due to thermal stress.

  4. Stress analysis of thermal sprayed coatings using a semi-destructive hole-drilling strain gauge method

    International Nuclear Information System (INIS)

    Dolhof, V.; Musil, J.; Cepera, M.; Zeman, J.

    1995-01-01

    Residual stress is an important parameter in coating technology since it often relates to the maximum coating thickness which can be deposited without spallation, and this applies to coatings produced by different thermal spray and thin film technologies. Indeed, the mechanisms by which residual stress is built up or locked into a coating depends markedly on the deposition process and coating structure (growth structure, phase composition) in the same way too. Methods for determining residual stresses in materials include both destructive and non-destructive methods. This contribution describes semi-destructive hole-drilling strain gauge method modified for measurement of residual stresses in thermal sprayed coatings. This method of stress analysis was used for determination of stress levels in thermal sprayed WC-17% Co coatings onto 13% Cr steel substrates. Results show that deposition conditions and final coating structure influence directly the residual stress level in the coatings. It is proved that semi-destructive hole-tube drilling measurement is effective reproducible method of coating stress analysis and good solution for optimization of deposition process

  5. Stochastic thermal stress analysis of clad cylindrical fuel elements

    International Nuclear Information System (INIS)

    Barrett, P.R.

    1975-01-01

    After a review of deterministic elastic thermal stress analysis by means of the displacement method for a cylindrical system in which the temperature distribution is not only radially variable but azimuthally and axially variable also, a method is shown for the determination of the statistical moments of the stress components when (a) the outer boundary of the cladding is a stochastic quantity, and (b) the uncertainties in the elastic and thermal constants of the materials and in the magnitude of the heat generation term are taken into account. A typical model is proposed for describing the statistics of the outer radius of the cladding which is a stochastic variable owing to uncertainties produced by the extrusion process. The theory is illustrated by means of a simple example by examining a meaningful reliability index and the relative importance of each of the uncertainties. (Auth.)

  6. Thermal stresses in the space shuttle orbiter: Analysis versus test

    International Nuclear Information System (INIS)

    Grooms, H.R.; Gibson, W.F. Jr.; Benson, P.L.

    1984-01-01

    Significant temperature differences occur between the internal structure and the outer skin of the Space Shuttle Orbiter as it returns from space. These temperature differences cause important thermal stresses. A finite element model containing thousands of degrees of freedom is used to predict these stresses. A ground test was performed to verify the prediction method. The analysis and test results compare favorably. (orig.)

  7. Early life thermal stress: Impact on future thermotolerance, stress response, behavior, and intestinal morphology in piglets exposed to a heat stress challenge during simulated transport

    Science.gov (United States)

    Study objectives were to evaluate the impact of early life thermal stress (ELTS) on thermoregulation, stress, and intestinal health of piglets subjected to a future heat stress (HS) challenge during simulated transport. Approximately 7 d after farrowing, 12 first parity gilts and their litters were ...

  8. Influence of overelastic loading on the stress intensity factor under thermal fatigue conditions

    International Nuclear Information System (INIS)

    Stamm, H.; Munz, D.

    1983-10-01

    Thermal shock loading often creates high thermal stresses which may exceed yield strength of the material in a surface layer. In this report the application of the linear elastic ΔK-concept in the case of cyclic thermal loading within the shakedown region is discussed. To this K-factors for an edge crack in a linear elastic - perfectly plastic plate are calculated using the weight function method and are compared with results obtained with the Finite Element Method. It is shown, that rearrangement stresses during plastic flow in the first cycle must be taken into account developing conservative approximation procedures. (orig.) [de

  9. Interplay between cytoskeletal stresses and cell adaptation under chronic flow.

    Directory of Open Access Journals (Sweden)

    Deepika Verma

    Full Text Available Using stress sensitive FRET sensors we have measured cytoskeletal stresses in α-actinin and the associated reorganization of the actin cytoskeleton in cells subjected to chronic shear stress. We show that long-term shear stress reduces the average actinin stress and this effect is reversible with removal of flow. The flow-induced changes in cytoskeletal stresses are found to be dynamic, involving a transient decrease in stress (phase-I, a short-term increase (3-6 min (Phase-II, followed by a longer-term decrease that reaches a minimum in ~20 min (Phase-III, before saturating. These changes are accompanied by reorganization of the actin cytoskeleton from parallel F-actin bundles to peripheral bundles. Blocking mechanosensitive ion channels (MSCs with Gd(3+ and GsMTx4 (a specific inhibitor eliminated the changes in cytoskeletal stress and the corresponding actin reorganization, indicating that Ca(2+ permeable MSCs participate in the signaling cascades. This study shows that shear stress induced cell adaptation is mediated via MSCs.

  10. Study on Stress Development in the Phase Transition Layer of Thermal Barrier Coatings

    Directory of Open Access Journals (Sweden)

    Yijun Chai

    2016-09-01

    Full Text Available Stress development is one of the significant factors leading to the failure of thermal barrier coating (TBC systems. In this work, stress development in the two phase mixed zone named phase transition layer (PTL, which grows between the thermally grown oxide (TGO and the bond coat (BC, is investigated by using two different homogenization models. A constitutive equation of the PTL based on the Reuss model is proposed to study the stresses in the PTL. The stresses computed with the proposed constitutive equation are compared with those obtained with Voigt model-based equation in detail. The stresses based on the Voigt model are slightly higher than those based on the Reuss model. Finally, a further study is carried out to explore the influence of phase transition proportions on the stress difference caused by homogenization models. Results show that the stress difference becomes more evident with the increase of the PTL thickness ratio in the TGO.

  11. Transient thermal stresses in an orthotropic rectangular plate with convective heat transfer at upper and lower surfaces

    International Nuclear Information System (INIS)

    Sugano, Yoshihiro; Nakanishi, Takanori; Ito, Masahiko; Saito, Koichi.

    1982-01-01

    Recently, anisotropic materials have been used widely for reactor core elements and fast flying objects, therefore, the problem of thermal stress in anisotropic bodies has been studied actively. In this study, the unsteady plane thermal stress in an orthotropic rectangular thin plate heated by the temperature of ambient medium was analyzed, taking the heat transfer on both surfaces into account. The influence that the anisotropy of material constants and the heat transfer on both surfaces exert on the temperature and thermal stress of the plate was examined. Moreover, in order to investigate into the effect of the aspect ratio of the plate on the temperature and thermal stress, the unsteady distributions of temperature and thermal stress in an orthotropic semi-infinite band, of which the end surfaces are heated by ambient medium, were analyzed. The numerical calculation was carried out, and the results are shown. Before, it was difficult to satisfy the boundary condition related to shearing stress, accordingly, the analysis has not been performed, but in this study, it was shown that the analysis is possible. (Kako, I.)

  12. Residual stress of particulate polymer composites with reduced thermal expansion

    International Nuclear Information System (INIS)

    Nishino, T; Kotera, M; Sugiura, Y

    2009-01-01

    Thermal expansion behavior was investigated for tangusten zirconium phosphate (Zr 2 (WO 4 )(PO 4 ) 2 (ZWP)) particulate filled poly(ether ether ketone) (PEEK) composite. ZWP is known as ceramic filler with a negative thermal expansion. By incorporating ZWP with 40 volume %, the linear thermal expansion coefficient of the PEEK composite was reduced to almost same value (2.53 X 10 -5 K -1 ) with that of aluminum. This decrease was found to be quite effective for the decrease of the residual stress at the interface between aluminum plate and the composite.

  13. People who live in a cold climate: thermal adaptation differences based on availability of heating.

    Science.gov (United States)

    Yu, J; Cao, G; Cui, W; Ouyang, Q; Zhu, Y

    2013-08-01

    Are there differences in thermal adaptation to cold indoor environments between people who are used to living in heating and non-heating regions in China? To answer this question, we measured thermal perceptions and physiological responses of young men from Beijing (where there are indoor space heating facilities in winter) and Shanghai (where there are not indoor space heating facilities in winter) during exposures to cold. Subjects were exposed to 12°C, 14°C, 16°C, 18°C, 20°C for 1 h. Subjects from Beijing complained of greater cold discomfort and demonstrated poorer physiological acclimatization to cold indoor environments than those from Shanghai. These findings indicate that people's chronic indoor thermal experience might be an important determinant of thermal adaptation. © 2012 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  14. Human Thermal Comfort and Heat Stress in an Outdoor Urban Arid Environment: A Case Study

    Directory of Open Access Journals (Sweden)

    A. M. Abdel-Ghany

    2013-01-01

    Full Text Available To protect humans from heat stress risks, thermal comfort and heat stress potential were evaluated under arid environment, which had never been made for such climate. The thermal indices THI, WBGT, PET, and UTCI were used to evaluate thermal comfort and heat stress. RayMan software model was used to estimate the PET, and the UTCI calculator was used for UTCI. Dry and wet bulb temperatures (Td, Tw, natural wet bulb temperature (Tnw, and globe temperature (Tg were measured in a summer day to be used in the calculation. The results showed the following. (i The thermal sensation and heat stress levels can be evaluated by either the PET or UTCI scales, and both are valid for extremely high temperature in the arid environment. (ii In the comfort zone, around 75% of individuals would be satisfied with the surrounding environment and feel comfortable during the whole day. (iii Persons are exposed to strong heat stress and would feel uncomfortable most of the daytime in summer. (iv Heat fatigue is expected with prolonged exposure to sun light and activity. (v During the daytime, humans should schedule their activities according to the highest permissible values of the WBGT to avoid thermal shock.

  15. Design and testing of botanical thermotropic actuator mechanisms in thermally adaptive building coverings

    Science.gov (United States)

    Barrett, Ronald M.; Barrett, Ronald P.; Barrett, Cassandra M.

    2017-09-01

    This paper lays out the inspiration, operational principles, analytical modeling and coupon testing of a new class of thermally adaptive building coverings. The fundamental driving concepts for these coverings are derived from various families of thermotropic plant structures. Certain plant cellular structures like those in Mimosa pudica (Sensitive Plant), Rhododendron leaves or Albizia julibrissin (Mimosa Tree), exhibit actuation physiology which depends on changes in cellular turgor pressures to generate motion. This form of cellular action via turgor pressure manipulation is an inspiration for a new field of thermally adaptive building coverings which use various forms of cellular foam to aid or enable actuation much like plant cells are used to move leaves. When exposed to high solar loading, the structures use the inherent actuation capability of pockets of air trapped in closed cell foam as actuators to curve plates upwards and outwards. When cold, these same structures curve back towards the building forming large convex pockets of dead air to insulate the building. This paper describes basic classical laminated plate theory models comparing theory and experiment of such coupons containing closed-cell foam actuators. The study concludes with a global description of the effectiveness of this class of thermally adaptive building coverings.

  16. Thermal Stress Analyses for a Multislug Beam NLC Positron Target(LCC-0090)

    International Nuclear Information System (INIS)

    Stein, W.

    2003-01-01

    The power deposition of an incident multislug electron beam in a tungsten-rhenium target and the resultant thermal shock stresses in the material have been modeled with a transient, dynamic, structural response finite element code. The Next Linear Collider electron beam is assumed split into two parts, with each part impinging on a 4 radiation lengths thick target. Two targets are required to avoid excessive thermal stresses in the targets. Each of the two beam parts is assumed broken up into four slugs, each two microseconds apart. Energy deposition from each slug occurs over 265 nanoseconds and results in heating of the target and pressure pulses straining the material. The rapid power deposition of the electron beam and the resultant temperature profile in the target generates stress and pressure waves in the material that are considerably larger than those calculated by a static analysis. The 6.22 GeV electron beam has a spot radius size of 1.6 mm and results in a maximum temperature jump of 438 C. Stress pressure pulses are induced in the material from the rapid thermal expansion of the hotter material with peak effective stresses reaching 78 ksi (5.3 x 10 8 Pa) on the back side of the target, which is less than one half of the yield strength of the tungsten/rhenium alloy and below the material fatigue limit

  17. Temperature field and thermal stress analysis of the HT-7U vacuum vessel

    International Nuclear Information System (INIS)

    Song Yuntao; Yao Damao; Wu Songtao; Weng Peide

    2000-01-01

    The HT-7U vacuum vessel is an all-metal-welded double-wall interconnected with toroidal and poloidal stiffening ribs. The channels formed between the ribs and walls are filled with boride water as a nuclear shielding. On the vessel surface facing the plasma are installed cable-based Ohmic heaters. Prior to plasma operation the vessel is to be baked out and discharge cleaned at about 250 degree C. During baking out the non-uniformity of temperature distribution on the vacuum vessel will bring about serious thermal stress that can damage the vessel. In order to determine and optimize the design of the HT-7U vacuum vessel, a three-dimensional finite element model was performed to analyse its temperature field and thermal stress. the maximal thermal stress appeared on the round of lower vertical port and maximal deformation located just on the region between the upper vertical port and the horizontal port. The results show that the reinforced structure has a good capability of withstanding the thermal loads

  18. Adaptation of intertidal biofilm communities is driven by metal ion and oxidative stresses

    KAUST Repository

    Zhang, Weipeng; Wang, Yong; Lee, On On; Tian, Renmao; Cao, Huiluo; Gao, Zhaoming; Li, Yongxin; Yu, Li; Xu, Ying; Qian, Pei-Yuan

    2013-01-01

    Marine organisms in intertidal zones are subjected to periodical fluctuations and wave activities. To understand how microbes in intertidal biofilms adapt to the stresses, the microbial metagenomes of biofilms from intertidal and subtidal zones were compared. The genes responsible for resistance to metal ion and oxidative stresses were enriched in both 6-day and 12-day intertidal biofilms, including genes associated with secondary metabolism, inorganic ion transport and metabolism, signal transduction and extracellular polymeric substance metabolism. In addition, these genes were more enriched in 12-day than 6-day intertidal biofilms. We hypothesize that a complex signaling network is used for stress tolerance and propose a model illustrating the relationships between these functions and environmental metal ion concentrations and oxidative stresses. These findings show that bacteria use diverse mechanisms to adapt to intertidal zones and indicate that the community structures of intertidal biofilms are modulated by metal ion and oxidative stresses.

  19. Adaptation of intertidal biofilm communities is driven by metal ion and oxidative stresses

    KAUST Repository

    Zhang, Weipeng

    2013-11-11

    Marine organisms in intertidal zones are subjected to periodical fluctuations and wave activities. To understand how microbes in intertidal biofilms adapt to the stresses, the microbial metagenomes of biofilms from intertidal and subtidal zones were compared. The genes responsible for resistance to metal ion and oxidative stresses were enriched in both 6-day and 12-day intertidal biofilms, including genes associated with secondary metabolism, inorganic ion transport and metabolism, signal transduction and extracellular polymeric substance metabolism. In addition, these genes were more enriched in 12-day than 6-day intertidal biofilms. We hypothesize that a complex signaling network is used for stress tolerance and propose a model illustrating the relationships between these functions and environmental metal ion concentrations and oxidative stresses. These findings show that bacteria use diverse mechanisms to adapt to intertidal zones and indicate that the community structures of intertidal biofilms are modulated by metal ion and oxidative stresses.

  20. Perceived Thermal Discomfort and Stress Behaviours Affecting Students’ Learning in Lecture Theatres in the Humid Tropics

    Directory of Open Access Journals (Sweden)

    Tamaraukuro Tammy Amasuomo

    2016-04-01

    Full Text Available The study investigated the relationship between students’ perceived thermal discomfort and stress behaviours affecting their learning in lecture theatres in the humid tropics. Two lecture theatres, LTH-2 and 3, at the Niger Delta University, Nigeria, were used for the study. Two groups of students from the Faculties of Agriculture and Engineering and the Department of Technology Education constituted the population. The sample size selected through random sampling for Groups A and B was 210 and 370 students, respectively. Objective and self-report instruments were used for data collection. The objective instrument involved physical measurement of the two lecture theatres and of the indoor temperature, relative humidity and air movement. The self-report instrument was a questionnaire that asked for the students perceived indoor thermal discomfort levels and the effect of indoor thermal comfort level on perceived stress behaviours affecting their learning. The objective indoor environmental data indicated thermal discomfort with an average temperature of 29–32 °C and relative humidity of 78% exceeding the ASHARE [1] and Olgyay [2].The students’ experienced a considerable level of thermal discomfort and also perceived that stress behaviours due to thermal discomfort affected their learning. Further, there were no significant differences in the perceived thermal discomfort levels of the two groups of students in LTH-2 and 3. Furthermore, stress behaviours affecting learning as perceived by the two groups of students did not differ significantly. In addition, no correlation existed between the perceived indoor thermal discomfort levels and stress behaviour levels affecting learning for students in LTH-2, because the arousal level of the students in the thermal environment was likely higher than the arousal level for optimal performance [3,4]. However, a correlation existed in the case of students in LTH-3, which was expected because it only

  1. Renal sympathetic nerve, blood flow, and epithelial transport responses to thermal stress.

    Science.gov (United States)

    Wilson, Thad E

    2017-05-01

    Thermal stress is a profound sympathetic stress in humans; kidney responses involve altered renal sympathetic nerve activity (RSNA), renal blood flow, and renal epithelial transport. During mild cold stress, RSNA spectral power but not total activity is altered, renal blood flow is maintained or decreased, and epithelial transport is altered consistent with a sympathetic stress coupled with central volume loaded state. Hypothermia decreases RSNA, renal blood flow, and epithelial transport. During mild heat stress, RSNA is increased, renal blood flow is decreased, and epithelial transport is increased consistent with a sympathetic stress coupled with a central volume unloaded state. Hyperthermia extends these directional changes, until heat illness results. Because kidney responses are very difficult to study in humans in vivo, this review describes and qualitatively evaluates an in vivo human skin model of sympathetically regulated epithelial tissue compared to that of the nephron. This model utilizes skin responses to thermal stress, involving 1) increased skin sympathetic nerve activity (SSNA), decreased skin blood flow, and suppressed eccrine epithelial transport during cold stress; and 2) increased SSNA, skin blood flow, and eccrine epithelial transport during heat stress. This model appears to mimic aspects of the renal responses. Investigations of skin responses, which parallel certain renal responses, may aid understanding of epithelial-sympathetic nervous system interactions during cold and heat stress. Copyright © 2016 Elsevier B.V. All rights reserved.

  2. An investigation of characteristics of thermal stress caused by fluid temperature fluctuation at a T-junction pipe

    International Nuclear Information System (INIS)

    Miyoshi, Koji; Nakamura, Akira; Utanohara, Yoichi

    2014-01-01

    Thermal fatigue cracking may initiate at a T-junction pipe where high and low temperature fluids flow in from different directions and mix. Thermal stress is caused by a temperature gradient in a structure and by its variation. It is possible to obtain stress distributions if the temperature distributions at the pipe inner surface are obtained by experiments. The wall temperature distributions at a T-junction pipe were measured by experiments. The thermal stress distributions were calculated using the experimental data. The circumferential and axial stress fluctuations were larger than the radial stress fluctuation range. The stress fluctuation at the position of the maximum stress fluctuation had 10sec period. The distribution of the stress fluctuation was similar to that of the temperature fluctuation. The large stress fluctuations were caused by the time variation of the heating region by the hot jet flow. (author)

  3. Average thermal stress in the Al+SiC composite due to its manufacturing process

    International Nuclear Information System (INIS)

    Miranda, Carlos A.J.; Libardi, Rosani M.P.; Marcelino, Sergio; Boari, Zoroastro M.

    2013-01-01

    The numerical analyses framework to obtain the average thermal stress in the Al+SiC Composite due to its manufacturing process is presented along with the obtained results. The mixing of Aluminum and SiC powders is done at elevated temperature and the usage is at room temperature. A thermal stress state arises in the composite due to the different thermal expansion coefficients of the materials. Due to the particles size and randomness in the SiC distribution, some sets of models were analyzed and a statistical procedure used to evaluate the average stress state in the composite. In each model the particles position, form and size are randomly generated considering a volumetric ratio (VR) between 20% and 25%, close to an actual composite. The obtained stress field is represented by a certain number of iso stress curves, each one weighted by the area it represents. Systematically it was investigated the influence of: (a) the material behavior: linear x non-linear; (b) the carbide particles form: circular x quadrilateral; (c) the number of iso stress curves considered in each analysis; and (e) the model size (the number of particles). Each of above analyzed condition produced conclusions to guide the next step. Considering a confidence level of 95%, the average thermal stress value in the studied composite (20% ≤ VR ≤ 25%) is 175 MPa with a standard deviation of 10 MPa. Depending on its usage, this value should be taken into account when evaluating the material strength. (author)

  4. Transposable elements as stress adaptive capacitors induce genomic instability in fungal pathogen Magnaporthe oryzae.

    Directory of Open Access Journals (Sweden)

    Sonia Chadha

    Full Text Available A fundamental problem in fungal pathogenesis is to elucidate the evolutionary forces responsible for genomic rearrangements leading to races with fitter genotypes. Understanding the adaptive evolutionary mechanisms requires identification of genomic components and environmental factors reshaping the genome of fungal pathogens to adapt. Herein, Magnaporthe oryzae, a model fungal plant pathogen is used to demonstrate the impact of environmental cues on transposable elements (TE based genome dynamics. For heat shock and copper stress exposed samples, eight TEs belonging to class I and II family were employed to obtain DNA profiles. Stress induced mutant bands showed a positive correlation with dose/duration of stress and provided evidences of TEs role in stress adaptiveness. Further, we demonstrate that genome dynamics differ for the type/family of TEs upon stress exposition and previous reports of stress induced MAGGY transposition has underestimated the role of TEs in M. oryzae. Here, we identified Pyret, MAGGY, Pot3, MINE, Mg-SINE, Grasshopper and MGLR3 as contributors of high genomic instability in M. oryzae in respective order. Sequencing of mutated bands led to the identification of LTR-retrotransposon sequences within regulatory regions of psuedogenes. DNA transposon Pot3 was identified in the coding regions of chromatin remodelling protein containing tyrosinase copper-binding and PWWP domains. LTR-retrotransposons Pyret and MAGGY are identified as key components responsible for the high genomic instability and perhaps these TEs are utilized by M. oryzae for its acclimatization to adverse environmental conditions. Our results demonstrate how common field stresses change genome dynamics of pathogen and provide perspective to explore the role of TEs in genome adaptability, signalling network and its impact on the virulence of fungal pathogens.

  5. Adaptive multiparameter control: application to a Rapid Thermal Processing process; Commande Adaptative Multivariable: Application a un Procede de Traitement Thermique Rapide

    Energy Technology Data Exchange (ETDEWEB)

    Morales Mago, S J

    1995-12-20

    In this work the problem of temperature uniformity control in rapid thermal processing is addressed by means of multivariable adaptive control. Rapid Thermal Processing (RTP) is a set of techniques proposed for semiconductor fabrication processes such as annealing, oxidation, chemical vapour deposition and others. The product quality depends on two mains issues: precise trajectory following and spatial temperature uniformity. RTP is a fabrication technique that requires a sophisticated real-time multivariable control system to achieve acceptable results. Modelling of the thermal behaviour of the process leads to very complex mathematical models. These are the reasons why adaptive control techniques are chosen. A multivariable linear discrete time model of the highly non-linear process is identified on-line, using an identification scheme which includes supervisory actions. This identified model, combined with a multivariable predictive control law allows to prevent the controller from systems variations. The control laws are obtained by minimization of a quadratic cost function or by pole placement. In some of these control laws, a partial state reference model was included. This reference model allows to incorporate an appropriate tracking capability into the control law. Experimental results of the application of the involved multivariable adaptive control laws on a RTP system are presented. (author) refs

  6. Coupled thermal stress analysis of a hollow circular cylinder with transversely isotropic properties

    International Nuclear Information System (INIS)

    Tanigawa, Y.; Ootao, Y.

    1987-01-01

    If we shall analyze the thermal stress problems exactly in a transient state in continuum media, discussed with both the coupling and inertia effect, it has be shown that the thermomechanical coupling term shows a significant role than the inertia term for the common commercial alloys. In the present paper, we have considered the continuum medium with transversely isotropic material property, which has an isotropic property in r-θ plane, and analyzed the transient thermal stress problem of an infinitely long hollow circular cylinder due to an axisymmetrical partial heating. In order to get the thermal and thermoelastic fundamental differential equations separated in each field, we have introduced a perturbation technique. And then, we have carried out numerical calculations for several values of thermal and thermoelastic orthotropical parameters. (orig./GL)

  7. Heat transfer and thermal stress analysis in grooved tubes

    Indian Academy of Sciences (India)

    Heat transfer and thermal stresses, induced by temperature differencesin the internally grooved tubes of heat transfer equipment, have been analysed numerically. The analysis has been conducted for four different kinds of internally grooved tubes and three different mean inlet water velocities. Constant temperature was ...

  8. Trade-offs in thermal adaptation: the need for a molecular to ecological integration.

    Science.gov (United States)

    Pörtner, Hans O; Bennett, Albert F; Bozinovic, Francisco; Clarke, Andrew; Lardies, Marco A; Lucassen, Magnus; Pelster, Bernd; Schiemer, Fritz; Stillman, Jonathon H

    2006-01-01

    Through functional analyses, integrative physiology is able to link molecular biology with ecology as well as evolutionary biology and is thereby expected to provide access to the evolution of molecular, cellular, and organismic functions; the genetic basis of adaptability; and the shaping of ecological patterns. This paper compiles several exemplary studies of thermal physiology and ecology, carried out at various levels of biological organization from single genes (proteins) to ecosystems. In each of those examples, trade-offs and constraints in thermal adaptation are addressed; these trade-offs and constraints may limit species' distribution and define their level of fitness. For a more comprehensive understanding, the paper sets out to elaborate the functional and conceptual connections among these independent studies and the various organizational levels addressed. This effort illustrates the need for an overarching concept of thermal adaptation that encompasses molecular, organellar, cellular, and whole-organism information as well as the mechanistic links between fitness, ecological success, and organismal physiology. For this data, the hypothesis of oxygen- and capacity-limited thermal tolerance in animals provides such a conceptual framework and allows interpreting the mechanisms of thermal limitation of animals as relevant at the ecological level. While, ideally, evolutionary studies over multiple generations, illustrated by an example study in bacteria, are necessary to test the validity of such complex concepts and underlying hypotheses, animal physiology frequently is constrained to functional studies within one generation. Comparisons of populations in a latitudinal cline, closely related species from different climates, and ontogenetic stages from riverine clines illustrate how evolutionary information can still be gained. An understanding of temperature-dependent shifts in energy turnover, associated with adjustments in aerobic scope and performance

  9. The thermal environment of the human being on the global scale.

    Science.gov (United States)

    Jendritzky, Gerd; Tinz, Birger

    2009-11-11

    The close relationship between human health, performance, well-being and the thermal environment is obvious. Nevertheless, most studies of climate and climate change impacts show amazing shortcomings in the assessment of the environment. Populations living in different climates have different susceptibilities, due to socio-economic reasons, and different customary behavioural adaptations. The global distribution of risks of hazardous thermal exposure has not been analysed before. To produce maps of the baseline and future bioclimate that allows a direct comparison of the differences in the vulnerability of populations to thermal stress across the world. The required climatological data fields are obtained from climate simulations with the global General Circulation Model ECHAM4 in T106-resolution. For the thermo-physiologically relevant assessment of these climate data a complete heat budget model of the human being, the 'Perceived Temperature' procedure has been applied which already comprises adaptation by clothing to a certain degree. Short-term physiological acclimatisation is considered via Health Related Assessment of the Thermal Environment. The global maps 1971-1980 (control run, assumed as baseline climate) show a pattern of thermal stress intensities as frequencies of heat. The heat load for people living in warm-humid climates is the highest. Climate change will lead to clear differences in health-related thermal stress between baseline climate and the future bioclimate 2041-2050 based on the 'business-as-usual' greenhouse gas scenario IS92a. The majority of the world's population will be faced with more frequent and more intense heat strain in spite of an assumed level of acclimatisation. Further adaptation measures are crucial in order to reduce the vulnerability of the populations. This bioclimatology analysis provides a tool for various questions in climate and climate change impact research. Considerations of regional or local scale require climate

  10. STRESSES IN CEMENT-CONCRETE PAVEMENT SURFACING CAUSED BY THERMAL SHOCK

    Directory of Open Access Journals (Sweden)

    M. K. Pshembaev

    2016-01-01

    Full Text Available It is necessary to mention specially so-called thermal shock among various impacts on highway surface. Ice layer is formed on a concrete surface during the winter period of pavement surfacing operation. Sodium chloride which lowers temperature of water-ice transition temperature and causes ice thawing at negative temperature is usually used to remove ice from the pavement surface. Consequently, temperature in the concrete laying immediately under a thawing ice layer is coming down with a run that leads to significant stresses. Such phenomenon is known as a thermal shock with a meaning of local significant change in temperature. This process is under investigation, it has practical importance for an estimation of strength and longevity of a cement-concrete pavement surfacing and consequently it is considered as rather topical issue. The purpose of investigations is to develop a mathematical model and determination of shock blow permissible gradients for a cementconcrete road covering. Finite difference method has been used in order to determine stressed and deformed condition of the cement-concrete pavement surfacing of highways. A computer program has been compiled and it permits to carry out calculation of a road covering at various laws of temperature distribution in its depth. Regularities in distribution of deformation and stresses in the cement-concrete pavement surfacing of highways at thermal shock have been obtained in the paper. A permissible parameter of temperature distribution in pavement surfacing thickness has been determined in the paper. A strength criterion based on the process of micro-crack formation and development in concrete has been used for making calculations. It has been established that the thermal shock causes significant temperature gradients on the cement-concrete surfacing that lead to rather large normal stresses in the concrete surface layer. The possibility of micro-crack formation in a road covering is

  11. Resistance of functional Lactobacillus plantarum strains against food stress conditions.

    Science.gov (United States)

    Ferrando, Verónica; Quiberoni, Andrea; Reinhemer, Jorge; Suárez, Viviana

    2015-06-01

    The survival of three Lactobacillus plantarum strains (Lp 790, Lp 813 and Lp 998) with functional properties was studied taking into account their resistance to thermal, osmotic and oxidative stress factors. Stress treatments applied were: 52 °C-15 min (Phosphate Buffer pH 7, thermal shock), H2O2 0.1% (p/v) - 30 min (oxidative shock) and NaCl aqueous solution at 17, 25 and 30% (p/v) (room temperature - 1 h, osmotic shock). The osmotic stress was also evaluated on cell growth in MRS broth added of 2, 4, 6, 8 and 10% (p/v) of NaCl, during 20 h at 30 °C. The cell thermal adaptation was performed in MRS broth, selecting 45 °C for 30 min as final conditions for all strains. Two strains (Lp 813 and Lp 998) showed, in general, similar behaviour against the three stress factors, being clearly more resistant than Lp 790. An evident difference in growth kinetics in presence of NaCl was observed between Lp 998 and Lp 813, Lp998 showing a higher optical density (OD570nm) than Lp 813 at the end of the assay. Selected thermal adaptation improved by 2 log orders the thermal resistance of both strains, but cell growth in presence of NaCl was enhanced only in Lp 813. Oxidative resistance was not affected with this thermal pre-treatment. These results demonstrate the relevance of cell technological resistance when selecting presumptive "probiotic" cultures, since different stress factors might considerably affect viability or/and performance of the strains. The incidence of stress conditions on functional properties of the strains used in this work are currently under research in our group. Copyright © 2014 Elsevier Ltd. All rights reserved.

  12. Mucus sugar content shapes the bacterial community structure in thermally stressed Acropora muricata

    Directory of Open Access Journals (Sweden)

    Sonny T.M. Lee

    2016-03-01

    Full Text Available It has been proposed that the chemical composition of a coral’s mucus can influence the associated bacterial community. However, information on this topic is rare, and non-existent for corals that are under thermal stress. This study therefore compared the carbohydrate composition of mucus in the coral Acropora muricata when subjected to increasing thermal stress from 26°C to 31°C, and determined whether this composition correlated with any changes in the bacterial community. Results showed that, at lower temperatures, the main components of mucus were N-acetyl glucosamine and C6 sugars, but these constituted a significantly lower proportion of the mucus in thermally-stressed corals. The change in the mucus composition coincided with a shift from a γ-Proteobacteria- to a Verrucomicrobiae- and α-Proteobacteria-dominated community in the coral mucus. Bacteria in the class Cyanobacteria also started to become prominent in the mucus when the coral was thermally stressed. The increase in the relative abundance of the Verrucomicrobiae at higher temperature was strongly associated with a change in the proportion of fucose, glucose and mannose in the mucus. Increase in the relative abundance of α-Proteobacteria were associated with GalNAc and glucose, while the drop in relative abundance of γ-Proteobacteria at high temperature coincided with changes in fucose and mannose. Cyanobacteria were highly associated with arabinose and xylose. Changes in mucus composition and the bacterial community in the mucus layer occurred at 29°C, which were prior to visual signs of coral bleaching at 31°C. A compositional change in the coral mucus, induced by thermal stress could therefore be a key factor leading to a shift in the associated bacterial community. This, in turn, has the potential to impact the physiological function of the coral holobiont.

  13. Adaptation of children to the new environment as a stress factor in the work of teachers in nursery school

    OpenAIRE

    Vondrová, Terezie

    2018-01-01

    The topic of the bachelor thesis is children's adaptation to the nursery school education as a stress factor for the teachers. The thesis examines five areas which may cause stress to the teachers working with newly come children during the adaptation period and describes strategies teachers employ in order to cope with the stress. The expected stress factors are: children's problematic behavior, school management, colleague and parental pressure exacting fast and smooth adaptation process an...

  14. Thermal residual stresses in amorphous thermoplastic polymers

    Science.gov (United States)

    Grassia, Luigi; D'Amore, Alberto

    2010-06-01

    An attempt to calculate the internal stresses in a cylindrically shaped polycarbonate (LEXAN-GE) component, subjected to an arbitrary cooling rate, will be described. The differential volume relaxation arising as a result of the different thermal history suffered by each body point was considered as the primary source of stresses build up [1-3]. A numerical routine was developed accounting for the simultaneous stress and structural relaxation processes and implemented within an Ansys® environment. The volume relaxation kinetics was modeled by coupling the KAHR (Kovacs, Aklonis, Hutchinson, Ramos) phenomenological theory [4] with the linear viscoelastic theory [5-7]. The numerical algorithm translates the specific volume theoretical predictions at each body point as applied non-mechanical loads acting on the component. The viscoelastic functions were obtained from two simple experimental data, namely the linear viscoelastic response in shear and the PVT (pressure volume temperature) behavior. The dimensionless bulk compliance was extracted from PVT data since it coincides with the memory function appearing in the KAHR phenomenological theory [7]. It is showed that the residual stress scales linearly with the logarithm of the Biot's number.

  15. Finite element simulation of stress evolution in thermal barrier coating systems

    Energy Technology Data Exchange (ETDEWEB)

    Bednarz, P.

    2007-07-01

    Gas turbine materials exposed to extreme high temperature require protective coatings. To design reliable components, a better understanding of the coating failure mechanisms is required. Damage in Thermal Barrier Coating Systems (TBCs) is related to oxidation of the Bond Coat, sintering of the ceramic, thermal mismatch of the material constituents, complex shape of the BC/TGO/TBC interface, redistribution of stresses via creep and plastic deformation and crack resistance. In this work, experimental data of thermo-mechanical properties of CMSX-4, MCrAlY (Bond Coat) and APS-TBC (partially stabilized zirconia), were implemented into an FE-model in order to simulate the stress development at the metal/ceramic interface. The FE model reproduced the specimen geometry used in corresponding experiments. It comprises a periodic unit cell representing a slice of the cylindrical specimen, whereas the periodic length of the unit cell equals an idealized wavelength of the rough metal/ceramic interface. Experimental loading conditions in form of thermal cycling with a dwelltime at high temperature and consideration of continuous oxidation were simulated. By a stepwise consideration of various material properties and processes, a reference model was achieved which most realistically simulated the materials behavior. The influences of systematic parameter variations on the stress development and critical sites with respect to possible crack paths were shown. Additionally, crack initiation and propagation at the peak of asperity at BC/TGO interface was calculated. It can be concluded that a realistic modeling of stress development in TBCs requires at least reliable data of i) BC and TGO plasticity, ii) BC and TBC creep, iii) continuous oxidation including in particular lateral oxidation, and iv) critical energy release rate for interfaces (BC/TGO, TGO/TBC) and for each layer. The main results from the performed parametric studies of material property variations suggest that

  16. FEM thermal and stress analysis of bonded GaN-on-diamond substrate

    Science.gov (United States)

    Zhai, Wenbo; Zhang, Jingwen; Chen, Xudong; Bu, Renan; Wang, Hongxing; Hou, Xun

    2017-09-01

    A three-dimensional thermal and stress analysis of bonded GaN on diamond substrate is investigated using finite element method. The transition layer thickness, thermal conductivity of transition layer, diamond substrate thickness and the area ratio of diamond and GaN are considered and treated appropriately in the numerical simulation. The maximum channel temperature of GaN is set as a constant value and its corresponding heat power densities under different conditions are calculated to evaluate the influences that the diamond substrate and transition layer have on GaN. The results indicate the existence of transition layer will result in a decrease in the heat power density and the thickness and area of diamond substrate have certain impact on the magnitude of channel temperature and stress distribution. Channel temperature reduces with increasing diamond thickness but with a decreasing trend. The stress is reduced by increasing diamond thickness and the area ratio of diamond and GaN. The study of mechanical and thermal properties of bonded GaN on diamond substrate is useful for optimal designs of efficient heat spreader for GaN HEMT.

  17. Finite element formulation for thermal stress analysis of thin reactor structures

    International Nuclear Information System (INIS)

    Kulak, R.F.; Kennedy, J.M.; Belytschko, T.B.

    1978-01-01

    This paper describes the formulation of a finite-element procedure for the thermal stress analysis of thin wall reactor components. A general temperature-dependent constituent relationship is derived from a Gibbs potential function and a temperature-dependent yield surface. This form of constitutive relationship is applicable to problems of small strain. A similar form of a hypoelastic-plastic type is also developed for large strains. The variation of the yield surface with temperature is based upon a temperature-dependent, work-hardening model. The model uses a temperature-equivalent stress-plastic strain diagram which is generated from isothermal unaxial stress-strain data. The above constitutive relationships are incorporated into two computer codes and a previously developed numerical algorithm is used with minor modifications. A set of problems is presented validating the thermal analysis capability of the computer codes to a variety of problem types. (Auth.)

  18. Stress recovery and cyclic behaviour of an Fe-Mn-Si shape memory alloy after multiple thermal activation

    Science.gov (United States)

    Hosseini, E.; Ghafoori, E.; Leinenbach, C.; Motavalli, M.; Holdsworth, S. R.

    2018-02-01

    The stress recovery and cyclic deformation behaviour of Fe-17Mn-5Si-10Cr-4Ni-1(V,C) shape memory alloy (Fe-SMA) strips, which are often used for pre-stressed strengthening of structural members, were studied. The evolution of recovery stress under different constraint conditions was studied. The results showed that the magnitude of the tensile stress in the Fe-SMA member during thermal activation can have a signification effect on the final recovery stress. The higher the tensile load in the Fe-SMA (e.g., caused by dead load or thermal expansion of parent structure during heating phase), the lower the final recovery stress. Furthermore, this study investigated the cyclic behaviour of the activated SMA followed by a second thermal activation. Although the magnitude of the recovery stress decreased during the cyclic loading, the second thermal activation could retrieve a significant part of the relaxed recovery stress. This observation suggests that the relaxation of recovery stress during cyclic loading is due to a reversible phase transformation-induced deformation (i.e., forward austenite-to-martensite transformation) rather than an irreversible dislocation-induced plasticity. Retrieval of the relaxed recovery stress by the reactivation process has important practical implications as the prestressing loss in pre-stressed civil structures can be simply recovered by reheating of the Fe-SMA elements.

  19. Effect of power history on the shape and the thermal stress of a large sapphire crystal during the Kyropoulos process

    Science.gov (United States)

    Nguyen, Tran Phu; Chuang, Hsiao-Tsun; Chen, Jyh-Chen; Hu, Chieh

    2018-02-01

    In this study, the effect of the power history on the shape of a sapphire crystal and the thermal stress during the Kyropoulos process are numerically investigated. The simulation results show that the thermal stress is strongly dependent on the power history. The thermal stress distributions in the crystal for all growth stages produced with different power histories are also studied. The results show that high von Mises stress regions are found close to the seed of the crystal, the highly curved crystal surface and the crystal-melt interface. The maximum thermal stress, which occurs at the crystal-melt interface, increases significantly in value as the crystal expands at the crown. After this, there is reduction in the maximum thermal stress as the crystal lengthens. There is a remarkable enhancement in the maximum von Mises stress when the crystal-melt interface is close to the bottom of the crucible. There are two obvious peaks in the maximum Von Mises stress, at the end of the crown stage and in the final stage, when cracking defects can form. To alleviate this problem, different power histories are considered in order to optimize the process to produce the lowest thermal stress in the crystal. The optimal power history is found to produce a significant reduction in the thermal stress in the crown stage.

  20. Numerical methods for calculating thermal residual stresses and hydrogen diffusion

    International Nuclear Information System (INIS)

    Leblond, J.B.; Devaux, J.; Dubois, D.

    1983-01-01

    Thermal residual stresses and hydrogen concentrations are two major factors intervening in cracking phenomena. These parameters were numerically calculated by a computer programme (TITUS) using the FEM, during the deposition of a stainless clad on a low-alloy plate. The calculation was performed with a 2-dimensional option in four successive steps: thermal transient calculation, metallurgical transient calculation (determination of the metallurgical phase proportions), elastic-plastic transient (plain strain conditions), hydrogen diffusion transient. Temperature and phase dependence of hydrogen diffusion coefficient and solubility constant. The following results were obtained: thermal calculations are very consistent with experiments at higher temperatures (due to the introduction of fusion and solidification latent heats); the consistency is not as good (by 70 degrees) for lower temperatures (below 650 degrees C); this was attributed to the non-introduction of gamma-alpha transformation latent heat. The metallurgical phase calculation indicates that the heat affected zone is almost entirely transformed into bainite after cooling down (the martensite proportion does not exceed 5%). The elastic-plastic calculations indicate that the stresses in the heat affected zone are compressive or slightly tensile; on the other hand, higher tensile stresses develop on the boundary of the heat affected zone. The transformation plasticity has a definite influence on the final stress level. The return of hydrogen to the clad during the bainitic transformation is but an incomplete phenomenon and the hydrogen concentration in the heat affected zone after cooling down to room temperature is therefore sufficient to cause cold cracking (if no heat treatment is applied). Heat treatments are efficient in lowering the hydrogen concentration. These results enable us to draw preliminary conclusions on practical means to avoid cracking. (orig.)

  1. Thermal Stress Analysis for Ceramics Stalk in the Low Pressure Die Casting Machine

    Science.gov (United States)

    Noda, Nao-Aki; Hendra, Nao-Aki; Takase, Yasushi; Li, Wenbin

    Low pressure die casting (LPDC) is defined as a net shape casting technology in which the molten metal is injected at high speeds and pressure into a metallic die. The LPDC process is playing an increasingly important role in the foundry industry as a low-cost and high-efficiency precision forming technique. The LPDC process is that the permanent die and filling systems are placed over the furnace containing the molten alloy. The filling of the cavity is obtained by forcing the molten metal by means of a pressurized gas in order to rise into a ceramic tube, which connects the die to the furnace. The ceramics tube called stalk has high temperature resistance and high corrosion resistance. However, attention should be paid to the thermal stress when the stalk is dipped into the molten aluminum. It is important to develop the design of the stalk to reduce the risk of fracture because of low fracture toughness of ceramics. In this paper, therefore, the finite element method is applied to calculate the thermal stresses when the stalk is dipped into the crucible by varying the dipping speeds and dipping directions. It is found that the thermal stress can be reduced by dipping slowly if the stalk is dipped into the crucible vertically, while the thermal stress can be reduced by dipping fast if it is dipped horizontally.

  2. Phylogeographic differentiation versus transcriptomic adaptation to warm temperatures in Zostera marina, a globally important seagrass.

    Science.gov (United States)

    Jueterbock, A; Franssen, S U; Bergmann, N; Gu, J; Coyer, J A; Reusch, T B H; Bornberg-Bauer, E; Olsen, J L

    2016-11-01

    Populations distributed across a broad thermal cline are instrumental in addressing adaptation to increasing temperatures under global warming. Using a space-for-time substitution design, we tested for parallel adaptation to warm temperatures along two independent thermal clines in Zostera marina, the most widely distributed seagrass in the temperate Northern Hemisphere. A North-South pair of populations was sampled along the European and North American coasts and exposed to a simulated heatwave in a common-garden mesocosm. Transcriptomic responses under control, heat stress and recovery were recorded in 99 RNAseq libraries with ~13 000 uniquely annotated, expressed genes. We corrected for phylogenetic differentiation among populations to discriminate neutral from adaptive differentiation. The two southern populations recovered faster from heat stress and showed parallel transcriptomic differentiation, as compared with northern populations. Among 2389 differentially expressed genes, 21 exceeded neutral expectations and were likely involved in parallel adaptation to warm temperatures. However, the strongest differentiation following phylogenetic correction was between the three Atlantic populations and the Mediterranean population with 128 of 4711 differentially expressed genes exceeding neutral expectations. Although adaptation to warm temperatures is expected to reduce sensitivity to heatwaves, the continued resistance of seagrass to further anthropogenic stresses may be impaired by heat-induced downregulation of genes related to photosynthesis, pathogen defence and stress tolerance. © 2016 John Wiley & Sons Ltd.

  3. Transient thermal stress distribution in a circular pipe heated externally with a periodically moving heat source

    International Nuclear Information System (INIS)

    Özışık, Gülşah; Genç, M. Serdar; Yapıcı, Hüseyin

    2012-01-01

    This study presents the effects of periodically moving heat source on a circular steel pipe heated partly from its outer surface under stagnant ambient conditions. While the pipe is heated with this heat source applied on a certain section having a thickness of heat flux, the water flows through it to transfer heat. It is assumed that the flow is a fully-developed laminar flow. The heat source moves along from one end of the outer to the other end with a constant speed and then returns to the first end with the same speed. It is assumed that the heat transfer rate has a constant value, and that the thermo-physical properties of the steel do not change with temperature (elastic analysis). The numerical calculations have been performed individually for a wide range of thermal conductivity of steel and for different thicknesses of heat flux. The moving heat source produces the non-uniform temperature gradient and the non-uniform effective thermal stress, and when it arrives at the ends of the pipe, the temperature and effective thermal stress ratio profiles rise more excessively. The tangential component is more dominant in the effective thermal stress than the radial component. Highlights: ► Moving heat source produces non-uniform temperature gradients and thermal stresses. ► When moving heat source arrives at ends of pipe, temperature gradients rise excessively. ► With increasing of heat flux thickness and thermal conductivity, the temperature gradients reduce. ► Temperature gradients in thermal boundary layers slightly increase. ► Tangential component is more dominant in thermal stress than radial component.

  4. Simulation of thermal stress and buckling instability in Si/Ge and Ge/Si core/shell nanowires.

    Science.gov (United States)

    Das, Suvankar; Moitra, Amitava; Bhattacharya, Mishreyee; Dutta, Amlan

    2015-01-01

    The present study employs the method of atomistic simulation to estimate the thermal stress experienced by Si/Ge and Ge/Si, ultrathin, core/shell nanowires with fixed ends. The underlying technique involves the computation of Young's modulus and the linear coefficient of thermal expansion through separate simulations. These two material parameters are combined to obtain the thermal stress on the nanowires. In addition, the thermally induced stress is perceived in the context of buckling instability. The analysis provides a trade-off between the geometrical and operational parameters of the nanostructures. The proposed methodology can be extended to other materials and structures and helps with the prediction of the conditions under which a nanowire-based device might possibly fail due to elastic instability.

  5. Rooting and early growth of red mangrove seedlings from thermally stressed trees

    International Nuclear Information System (INIS)

    Banus, M.D.; Kolehmainen, S.E.

    At Guayanilla on the south coast of Puerto Rico a fossil fueled electric generating station of 1100 MW(e) discharges its cooling water into a nearly enclosed lagoon of about 25 hectares area. The plume and lagoon typically have water temperatures 10 0 C and 8 0 C above ambient so that the winter and summer lagoon temperatures are 34 and 39 0 C, respectively. The north, east, and south shores of this lagoon have extensive stands of red and black mangrove trees which are visibly stressed by the elevated temperatures. Ripe red mangrove seedlings from the bearing trees are significantly smaller than those from trees in Guayanilla Bay not thermally stressed and in unpolluted bays from western Puerto Rico. Seedlings from thermally stressed trees developed negative buoyancy and initial roots faster but first pair of leaves slower than seedlings from control areas. This behavior will be discussed in relation to the propagation of seedlings from non-stressed areas. (U.S.)

  6. Study on application of green's function method in thermal stress rapid calculation

    International Nuclear Information System (INIS)

    Zhang Guihe; Duan Yuangang; Xu Xiao; Chen Rong

    2013-01-01

    This paper presents a quick and accuracy thermal stress calculation method, the Green's Function Method, which is a combination of finite element method and numerical algorithm method. Thermal stress calculation of Safe Injection Nozzle of Reactor Coolant Line of PWR plant is performed with Green's function method for heatup and cooldown thermal transients as a demonstration example, and the result is compared with finite element method to verify the rationality and accuracy of this method. The advantage and disadvantage of the Green's function method and the finite element method are also compared. (authors)

  7. Residual stress change by thermal annealing in amorphous Sm-Fe-B thin films

    International Nuclear Information System (INIS)

    Na, S.M.; Suh, S.J.; Kim, H.J.; Lim, S.H.

    2002-01-01

    The change in the residual stress and its effect on mechanical bending and magnetic properties of sputtered amorphous Sm-Fe-B thin films are investigated as a function of annealing temperature. Two stress components of intrinsic compressive stress and tensile stress due to the difference of the thermal expansion coefficients between the substrate and thin film are used to explain the stress state in as-deposited thin films, and the annealing temperature dependence of residual stress, mechanical bending and magnetic properties

  8. A protocol for analysing thermal stress in insects using infrared thermography.

    Science.gov (United States)

    Gallego, Belén; Verdú, José R; Carrascal, Luis M; Lobo, Jorge M

    2016-02-01

    The study of insect responses to thermal stress has involved a variety of protocols and methodologies that hamper the ability to compare results between studies. For that reason, the development of a protocol to standardize thermal assays is necessary. In this sense, infrared thermography solves some of the problems allowing us to take continuous temperature measurements without handling the individuals, an important fact in cold-blooded organisms like insects. Here, we present a working protocol based on infrared thermography to estimate both cold and heat thermal stress in insects. We analyse both the change in the body temperature of individuals and their behavioural response. In addition, we used partial least squares regression for the statistical analysis of our data, a technique that solves the problem of having a large number of variables and few individuals, allowing us to work with rare or endemic species. To test our protocol, we chose two species of congeneric, narrowly distributed dung beetles that are endemic to the southeastern part of the Iberian Peninsula. With our protocol we have obtained five variables in the response to cold and twelve in the response to heat. With this methodology we discriminate between the two flightless species of Jekelius through their thermal response. In response to cold, Jekelius hernandezi showed a higher rate of cooling and reached higher temperatures of stupor and haemolymph freezing than Jekelius punctatolineatus. Both species displayed similar thermoregulation ranges before reaching lethal body temperature with heat stress. Overall, we have demonstrated that infrared thermography is a suitable method to assess insect thermal responses with a high degree of sensitivity, allowing for the discrimination between closely related species. Copyright © 2016 Elsevier Ltd. All rights reserved.

  9. Radio-adaptive response

    International Nuclear Information System (INIS)

    Ikushima, Takaji

    1991-01-01

    An adaptive response to radiation stress was found in cultured Chinese hamster V79 cells, as a suppressed induction of micronuclei (MNs) and sister chromatid exchanges (SCEs) in the cells conditioned by very low doses. The important characteristics of the novel chromosomal response, called radio-adaptive response (RAR), that have newly emerged in this study are: 1) Low doses of beta-rays from tritiated water (HTO) as well as tritiated thymidine can cause the RAR. 2) Thermal neutrons, a high LET radiation, can not act as tritium beta-rays or gamma-rays. 3) The RAR expression is suppressed by an inhibition of protein synthesis. 4) Several proteins are newly synthesized concurrently with the RAR expression after adapting doses, viewed by two-dimensional electrophoresis of cellular proteins. These results suggest that the RAR is an adaptive chromosomal DNA repair induced by very low doses of low LET radiations under restricted conditions, accompanying the inducible specific gene expression. (author)

  10. A systems biology analysis of long and short-term memories of osmotic stress adaptation in fungi

    Directory of Open Access Journals (Sweden)

    You Tao

    2012-05-01

    Full Text Available Abstract Background Saccharomyces cerevisiae senses hyperosmotic conditions via the HOG signaling network that activates the stress-activated protein kinase, Hog1, and modulates metabolic fluxes and gene expression to generate appropriate adaptive responses. The integral control mechanism by which Hog1 modulates glycerol production remains uncharacterized. An additional Hog1-independent mechanism retains intracellular glycerol for adaptation. Candida albicans also adapts to hyperosmolarity via a HOG signaling network. However, it remains unknown whether Hog1 exerts integral or proportional control over glycerol production in C. albicans. Results We combined modeling and experimental approaches to study osmotic stress responses in S. cerevisiae and C. albicans. We propose a simple ordinary differential equation (ODE model that highlights the integral control that Hog1 exerts over glycerol biosynthesis in these species. If integral control arises from a separation of time scales (i.e. rapid HOG activation of glycerol production capacity which decays slowly under hyperosmotic conditions, then the model predicts that glycerol production rates elevate upon adaptation to a first stress and this makes the cell adapts faster to a second hyperosmotic stress. It appears as if the cell is able to remember the stress history that is longer than the timescale of signal transduction. This is termed the long-term stress memory. Our experimental data verify this. Like S. cerevisiae, C. albicans mimimizes glycerol efflux during adaptation to hyperosmolarity. Also, transient activation of intermediate kinases in the HOG pathway results in a short-term memory in the signaling pathway. This determines the amplitude of Hog1 phosphorylation under a periodic sequence of stress and non-stressed intervals. Our model suggests that the long-term memory also affects the way a cell responds to periodic stress conditions. Hence, during osmohomeostasis, short-term memory is

  11. Investigations in thermal fields and stress fields induced by electron beam welding

    International Nuclear Information System (INIS)

    Basile, G.

    1979-12-01

    This document presents the thermal study of electron beam welding and identifies stresses and strains from welding: description of the operating principles of the electron gun and characterization of various welding parameters, examination of the temperature fields during electron beam welding development of various mathematic models and comparison with experimental results, measurement and calculation of stresses and strains in the medium plane of the welding assembly, residual stresses analysis [fr

  12. ACTIONS OF PROLACTIN IN THE BRAIN: FROM PHYSIOLOGICAL ADAPTATIONS TO STRESS AND NEUROGENESIS TO PSYCHOPATHOLOGY

    Directory of Open Access Journals (Sweden)

    Luz eTorner

    2016-03-01

    Full Text Available Prolactin is one of the most versatile hormones known. It is considered an adaptive hormone due to the key roles it plays in the modulation of the stress response and during pregnancy and lactation. Within the brain, prolactin acts as a neuropeptide to promote physiological responses related to reproduction, stress adaptation, neurogenesis, and neuroprotection. The action of prolactin on the nervous system contributes to the wide array of changes that occur in the female brain during pregnancy and result in the attenuation of the hypothalamic pituitary adrenal axis. Together, all these changes promote behavioral and physiological adaptations of the new mother to enable reproductive success. Brain adaptations driven by prolactin are also important for the regulation of maternal emotionality and wellbeing Prolactin also affects the male brain during the stress response but its effects have been less studied. Prolactin regulates neurogenesis both in the subventricular zone and in the hippocampus. Therefore, alterations in the prolactin system due to stress, or exposure to substances that reduce neurogenesis or other conditions, could contribute to maladaptive responses and pathological behavioral outcomes. Here we review the prolactin system and the role it plays in the modulation of stress response and emotion regulation. We discuss the effects of prolactin on neurogenesis and neuroprotection, the putative neuronal mechanisms underlying these effects, and their contribution to the onset of psychopathological states like depression.

  13. Effect of Thermal Mechanical Behaviors of Cu on Stress Distribution in Cu-Filled Through-Silicon Vias Under Heat Treatment

    Science.gov (United States)

    Zhao, Xuewei; Ma, Limin; Wang, Yishu; Guo, Fu

    2018-01-01

    Through-silicon vias (TSV) are facing unexpected thermo-mechanical reliability problems due to the coefficient of thermal expansion (CTE) mismatch between various materials in TSVs. During applications, thermal stresses induced by CTE mismatch will have a negative impact on other devices connecting with TSVs, even leading to failure. Therefore, it is essential to investigate the stress distribution evolution in the TSV structure under thermal loads. In this report, TSVs were heated to 450°C at different heating rates, then cooled down to room temperature after a 30-min dwelling. After heating treatment, TSV samples exhibited different Cu deformation behaviors, including Cu intrusion and protrusion. Based on the different Cu deformation behaviors, stress in Si around Cu vias of these samples was measured and analyzed. Results analyzed by Raman spectrums showed that the stress distribution changes were associated with Cu deformation behaviors. In the area near the Cu via, Cu protrusion behavior might aggravate the stress in Si obtained from the Raman measurement, while Cu intrusion might alleviate the stress. The possible reason was that in this area, the compressive stress σ_{θ } induced by thermal loads might be the dominant stress. In the area far from the Cu via, thermal loads tended to result in a tensile stress state in Si.

  14. Fast Adaptive Thermal Camouflage Based on Flexible VO₂/Graphene/CNT Thin Films.

    Science.gov (United States)

    Xiao, Lin; Ma, He; Liu, Junku; Zhao, Wei; Jia, Yi; Zhao, Qiang; Liu, Kai; Wu, Yang; Wei, Yang; Fan, Shoushan; Jiang, Kaili

    2015-12-09

    Adaptive camouflage in thermal imaging, a form of cloaking technology capable of blending naturally into the surrounding environment, has been a great challenge in the past decades. Emissivity engineering for thermal camouflage is regarded as a more promising way compared to merely temperature controlling that has to dissipate a large amount of excessive heat. However, practical devices with an active modulation of emissivity have yet to be well explored. In this letter we demonstrate an active cloaking device capable of efficient thermal radiance control, which consists of a vanadium dioxide (VO2) layer, with a negative differential thermal emissivity, coated on a graphene/carbon nanotube (CNT) thin film. A slight joule heating drastically changes the emissivity of the device, achieving rapid switchable thermal camouflage with a low power consumption and excellent reliability. It is believed that this device will find wide applications not only in artificial systems for infrared camouflage or cloaking but also in energy-saving smart windows and thermo-optical modulators.

  15. Influence of temperature on alkali stress adaptation in Listeria monocytogenes

    Science.gov (United States)

    Listeria monocytogenes cells may induce alkali stress adaptation when exposed to sublethal concentrations of alkaline cleaners and sanitizers that may be frequently used in the food processing environment. In the present study, the effect of temperature on the induction and the stability of such alk...

  16. Spalling stress in oxidized thermal barrier coatings evaluated by X-ray diffraction method

    Energy Technology Data Exchange (ETDEWEB)

    Suzuki, K. [Faculty of Education and Human Sciences, Niigata Univ., Niigata (Japan); Tanaka, K. [Dept. of Mechanical Engineering, Nagoya Univ., Furoh-cho, Chikusa-ku, Nagoya (Japan)

    2005-07-01

    The spallation of thermal barrier coatings (TBCs) is promoted by thermally grown oxide (TGO). To improve TBCs, it is very important to understand the influence of TGO on the spalling stress. In this study 'the TBCs were oxidized at 1373 K for four different periods: 0, 500,1000 and 2000 h. The distribution of the in-plane stress in oxidized TBCs, {sigma}{sub 1}, was obtained by repeating the X-ray stress measurement with low energy X-rays after successive removal of the surface layer. The distribution of the out-of-plane stress, {sigma}{sub 1} - {sigma}{sub 3}, was measured with hard synchrotron X-rays, because high energy X-rays have a large penetration depth. From the results by the low and high energy X-rays, the spalling stress in the oxidized TBCs, {sigma}{sub 3}, was evaluated. The evaluated value of the spalling stress for the oxidized TBC was a small tension beneath the surface, but steeply increased near the interface between the top and bond coating. This large tensile stress near the interface is responsible for the spalling of the top coating. (orig.)

  17. Differentially expressed genes associated with adaptation to different thermal environments in three sympatric Cuban Anolis lizards.

    Science.gov (United States)

    Akashi, Hiroshi D; Cádiz Díaz, Antonio; Shigenobu, Shuji; Makino, Takashi; Kawata, Masakado

    2016-05-01

    How animals achieve evolutionary adaptation to different thermal environments is an important issue for evolutionary biology as well as for biodiversity conservation in the context of recent global warming. In Cuba, three sympatric species of Anolis lizards (Anolis allogus, A. homolechis and A. sagrei) inhabit different thermal microhabitats, thereby providing an excellent opportunity to examine how they have adapted to different environmental temperatures. Here, we performed RNA-seq on the brain, liver and skin tissues from these three species to analyse their transcriptional responses at two different temperatures. In total, we identified 400, 816 and 781 differentially expressed genes (DEGs) between the two temperatures in A. allogus, A. homolechis and A. sagrei, respectively. Only 62 of these DEGs were shared across the three species, indicating that global transcriptional responses have diverged among these species. Gene ontology (GO) analysis showed that large numbers of ribosomal protein genes were DEGs in the warm-adapted A. homolechis, suggesting that the upregulation of protein synthesis is an important physiological mechanism in the adaptation of this species to hotter environments. GO analysis also showed that GO terms associated with circadian regulation were enriched in all three species. A gene associated with circadian regulation, Nr1d1, was detected as a DEG with opposite expression patterns between the cool-adapted A. allogus and the hot-adapted A. sagrei. Because the environmental temperature fluctuates more widely in open habitats than in forests throughout the day, the circadian thermoregulation could also be important for adaptation to distinct thermal habitats. © 2016 John Wiley & Sons Ltd.

  18. Field study on behaviors and adaptation of elderly people and their thermal comfort requirements in residential environments.

    Science.gov (United States)

    Hwang, R-L; Chen, C-P

    2010-06-01

    This study investigated the thermal sensation of elderly people in Taiwan, older than 60 years, in indoor microclimate at home, and their requirements for establishing thermal comfort. The study was conducted using both a thermal sensation questionnaire and measurement of indoor climatic parameters underlying the thermal environment. Survey results were compared with those reported by Cheng and Hwang (2008, J. Tongji Univ., 38, 817-822) for non-elders to study the variation between different age groups in requirements of indoor thermal comfort. The results show that the predominant strategy of thermal adaptation for elders was window-opening in the summer and clothing adjustment in the winter. The temperature of thermal neutrality was 25.2 degrees C and 23.2 degrees C for the summer and the winter, respectively. Logistically regressed probit modeling on percentage of predicted dissatisfied (PPD) against mean thermal sensation vote revealed that the sensation votes corresponding to a PPD of 20% were +/- 0.75 for elders, about +/- 0.10 less than the levels projected by ISO 7730 model. The range of operative temperature for 80% thermal acceptability for elders in the summer was 23.2-27.1 degrees C, narrower than the range of 23.0-28.6 degrees C reported for non-elders. This is likely a result of a difference in the selection of adaptive strategies. Taiwan in the last decade has seen a rapid growth in the elderly population in its societal structure, and as such the quality of indoor thermal comfort increasingly concerns the elderly people. This study presents the results from field-surveying elders residing in major geographical areas of Taiwan, and discusses the requirements of these elders for indoor thermal comfort in different seasons. Through a comparison with the requirements by non-elders, this study demonstrates the unique sensitivity of elders toward indoor thermal quality and the selection of adaptive strategies that need to be considered when a thermal

  19. The effects of location, thermal stress, and residual stress on corner cracks in nozzles with cladding

    International Nuclear Information System (INIS)

    Besuner, P.M.; Cohen, L.M.; McLean, J.L.

    1977-01-01

    The stress intensity factors (Ksub(I)) for corner cracks in a boiling water reactor feedwater nozzle with stainless steel cladding are obtained for loading by internal pressure, and a fluid quench in the nozzle. Conditions with and without residual stress in the component are considered. The residual stress is simulated by means of a reference temperature change. The stress distribution for the uncracked structure is obtained from a three-dimensional finite element model. A three-dimensional influence function (IF) method, in conjunction with the boundary-integral equation method for structural analysis is employed to compute Ksub(I) values from the uncracked structure's stress distribution. It is concluded that the effects on Ksub(I) of location, thermal stresses, and residual stresses are significant and generally too complex to evaluate without advanced numerical procedures. The ulilized combination of finite element analysis of the uncracked structure and three-dimensional influence function analysis of the cracked structure is demonstrated and endorsed. (Auth.)

  20. A study on the bonding residual thermal stress analysis of dissimilar materials using boundary element method

    International Nuclear Information System (INIS)

    Yi, Won; Yu, Yeong Chul; Jeong, Eui Seob; Lee, Chang Ho

    1995-01-01

    It is very important to evaluate the bonding residual thermal stress in dissimilar materials such as LSI package. In this study, the bonding residual thermal stress was calculated using the boundary element method, varing with the sub-element, geometry of specimen and adhesive thickness. The present results reveal a stress singularity at the edge of the interface, therefore the bonding strength of metal/resin interface can be estimated by taking into account it.

  1. Thermoregulation and thermal perception in the cold and heat before and after intermittent heat adaptation

    Science.gov (United States)

    Issing, K.; Fuhr, E.

    1986-09-01

    Students wearing swim suits were exposed for 30 min to neutral room temperature (TR=28‡C). During the following 60 min they were subjected to gradual decreases or increases of room temperature reaching 12‡C or 45‡C, respectively. Static thermal stimuli were applied to the palms of the right (38‡C) and left (25‡C) hands. Hands and feet of all subjects were thermally isolated at 22‡C ambient temperature. General thermal comfort (GTC), local thermal comfort (LTC), skin blood flow (which is proportional to heat transport index λ) several body temperatures, oxygen-consumption(dot V_{O_2 } ), and sweat rate (S), were measured. After moderate intermittent heat exposures (7 times for 1h at TR=42.5‡C) the experiments started again. From GTC, LTC, or λ as functions of TR, no new knowledge about thermoregulatory or adaptive mechanisms was available. The high λ in the cold stimulated left hand, however, and the oscillatory thresholds (λOSC) for rhythmic vasomotion indicated the peripheral influence of skin temperature, as well as local, mean skin temperature (¯Ts) and core temperature. When exposed to moderate temperature decreases or increases the body seems to react only with increasing thermal resistance by vasoconstriction or an increase of sweat rate, respectively. Moderate heat adaptation is only able to raise sweat rate, but not the thresholds and gain of the S-function. We assume that functional studies of adaptive modifications in humans must be conducted at temperatures greatly beyond those used in these experiments.

  2. Ask yeast how to burn your fats: lessons learned from the metabolic adaptation to salt stress.

    Science.gov (United States)

    Pascual-Ahuir, Amparo; Manzanares-Estreder, Sara; Timón-Gómez, Alba; Proft, Markus

    2018-02-01

    Here, we review and update the recent advances in the metabolic control during the adaptive response of budding yeast to hyperosmotic and salt stress, which is one of the best understood signaling events at the molecular level. This environmental stress can be easily applied and hence has been exploited in the past to generate an impressively detailed and comprehensive model of cellular adaptation. It is clear now that this stress modulates a great number of different physiological functions of the cell, which altogether contribute to cellular survival and adaptation. Primary defense mechanisms are the massive induction of stress tolerance genes in the nucleus, the activation of cation transport at the plasma membrane, or the production and intracellular accumulation of osmolytes. At the same time and in a coordinated manner, the cell shuts down the expression of housekeeping genes, delays the progression of the cell cycle, inhibits genomic replication, and modulates translation efficiency to optimize the response and to avoid cellular damage. To this fascinating interplay of cellular functions directly regulated by the stress, we have to add yet another layer of control, which is physiologically relevant for stress tolerance. Salt stress induces an immediate metabolic readjustment, which includes the up-regulation of peroxisomal biomass and activity in a coordinated manner with the reinforcement of mitochondrial respiratory metabolism. Our recent findings are consistent with a model, where salt stress triggers a metabolic shift from fermentation to respiration fueled by the enhanced peroxisomal oxidation of fatty acids. We discuss here the regulatory details of this stress-induced metabolic shift and its possible roles in the context of the previously known adaptive functions.

  3. FEM thermal and stress analysis of bonded GaN-on-diamond substrate

    Directory of Open Access Journals (Sweden)

    Wenbo Zhai

    2017-09-01

    Full Text Available A three-dimensional thermal and stress analysis of bonded GaN on diamond substrate is investigated using finite element method. The transition layer thickness, thermal conductivity of transition layer, diamond substrate thickness and the area ratio of diamond and GaN are considered and treated appropriately in the numerical simulation. The maximum channel temperature of GaN is set as a constant value and its corresponding heat power densities under different conditions are calculated to evaluate the influences that the diamond substrate and transition layer have on GaN. The results indicate the existence of transition layer will result in a decrease in the heat power density and the thickness and area of diamond substrate have certain impact on the magnitude of channel temperature and stress distribution. Channel temperature reduces with increasing diamond thickness but with a decreasing trend. The stress is reduced by increasing diamond thickness and the area ratio of diamond and GaN. The study of mechanical and thermal properties of bonded GaN on diamond substrate is useful for optimal designs of efficient heat spreader for GaN HEMT.

  4. Modeling of Short-Circuit-Related Thermal Stress in Aged IGBT Modules

    DEFF Research Database (Denmark)

    Bahman, Amir Sajjad; Iannuzzo, Francesco; Uhrenfeldt, Christian

    2017-01-01

    In this paper, the thermal stress on bond wires of aged IGBT modules under short-circuit conditions has been studied with respect to different solder delamination levels. To ensure repeatable test conditions, ad-hoc DBC (direct bond copper) samples with delaminated solder layers have been purposely...... in the surface temperature distribution, which confirms the hypothesis that short-circuit events produce significantly uneven stresses on bond wires....

  5. Prediction of Short-Circuit-Related Thermal Stress in Aged IGBT Modules

    DEFF Research Database (Denmark)

    Bahman, Amir Sajjad; Iannuzzo, Francesco; Uhrenfeldt, Christian

    2016-01-01

    In this paper, the thermal stress on bond wires of aged IGBT modules under short-circuit conditions has been studied with respect to different solder delamination levels. To ensure repeatable test conditions, ad-hoc DBC (direct bond copper) samples with delaminated solder layers have been purposely...... in the surface temperature distribution which confirms the hypothesis that short-circuit events produce significantly uneven stresses on bond wires....

  6. Thermal stress prediction in mirror and multilayer coatings.

    Science.gov (United States)

    Cheng, Xianchao; Zhang, Lin; Morawe, Christian; Sanchez Del Rio, Manuel

    2015-03-01

    Multilayer optics for X-rays typically consist of hundreds of periods of two types of alternating sub-layers which are coated on a silicon substrate. The thickness of the coating is well below 1 µm (tens or hundreds of nanometers). The high aspect ratio (∼10(7)) between the size of the optics and the thickness of the multilayer can lead to a huge number of elements (∼10(16)) for the numerical simulation (by finite-element analysis using ANSYS code). In this work, the finite-element model for thermal-structural analysis of multilayer optics has been implemented using the ANSYS layer-functioned elements. The number of meshed elements is considerably reduced and the number of sub-layers feasible for the present computers is increased significantly. Based on this technique, single-layer coated mirrors and multilayer monochromators cooled by water or liquid nitrogen are studied with typical parameters of heat-load, cooling and geometry. The effects of cooling-down of the optics and heating of the X-ray beam are described. It is shown that the influences from the coating on temperature and deformation are negligible. However, large stresses are induced in the layers due to the different thermal expansion coefficients between the layer and the substrate materials, which is the critical issue for the survival of the optics. This is particularly true for the liquid-nitrogen cooling condition. The material properties of thin multilayer films are applied in the simulation to predict the layer thermal stresses with more precision.

  7. Thermal perceptions, general adaptation methods and occupant's idea about the trade-off between thermal comfort and energy saving in hot-humid regions

    Energy Technology Data Exchange (ETDEWEB)

    Hwang, Ruey-Lung [Department of Occupational Safety and Health, China Medical University, 91 Huseh-Shin Road, Taichung 404 (China); Cheng, Ming-Jen [Department of Architecture, Feng Chia University, 100 Wen-Hwa Road, Seatwen, Taichung 407 (China); Lin, Tzu-Ping [Department of Leisure Planning, National Formosa University, 64 Wen-Hua Road, Huwei, Yunlin 632 (China); Ho, Ming-Chin [Architecture and Building Research Institute, Ministry of the Interior, 13F, No. 200, Sec. 3, Bei-sin Road, Sindian City, Taipei County 231 (China)

    2009-06-15

    A field study conducted in workplaces and residences in Taiwan is carried out to clarify two questions in detail: (1) do people in the tropical climate regions demonstrate a correlation between thermal sensation and thermal dissatisfaction the same as the PMV-PPD formula in the ISO 7730; and (2) does the difference in opportunities to choose from a variety of methods to achieve thermal comfort affects thermal perceptions of occupants? A new predicted formula of percentage of dissatisfied (PD) relating to mean thermal sensation votes (TSVs) is proposed for hot and humid regions. Besides an increase in minimum rate of dissatisfied from 5% to 9%, a shift of the TSV with minimum PD to the cool side of sensation scale is suggested by the new proposed formula. It also reveals that the limits of TSV corresponding to 80% acceptability for hot and humid regions are -1.45 and +0.65 rather than -0.85 and +0.85 suggested by ISO 7730. It is revealed in the findings that the effectiveness, availability and cost of a thermal adaptation method can affect the interviewees' thermal adaptation behaviour. According to the discussion of interviewees' idea about the trade-off between thermal comfort and energy saving, it is found that an energy-saving approach at the cost of sacrificing occupant's thermal comfort is difficult to set into action, but those ensure the occupant's comfort are more acceptable and can be easily popularized. (author)

  8. A method of solution of the elastic-plastic thermal stress problem

    International Nuclear Information System (INIS)

    Rafalski, P.

    1975-01-01

    The purpose of the work is an improvement of the numerical technique for calculating the thermal stress distribution in an elastic-plastic structural element. The work consists of two parts. In the first a new method of solution of the thermal stress problem for the elastic-plastic body is presented. In the second a particular numerical technique, based on the above method, for calculating the stress and strain fields is proposed. A new mathematical approach consists in treating the stress and strain fields as mathematical objects defined in the space-time domain. The methods commonly applied use the stress and strain fields defined in the space domain and establish the relations between them at a given instant t. They reduce the problem to the system of ordinary differential equations with respect to time, which are usually solved with a step-by-step technique. The new method reduces the problem to the system of nonlinear algebraic equations. In the work the Hilbert space of admissible tensor fields is constructed. This space is the orthogonal sum of two subspaces: of statically admissible and kinematically admissible fields. Two alternative orthogonality conditions, which correspond to the equilibrium and compatibility equations with the appropriate boundary conditions, are derived. The results of the work are to be used for construction of the computer program for calculation the stress and strain fields in the elastic-plastic body with a prescribed temperature field in the interior and appropriate displacement and force conditions on the boundary

  9. Initial assessment of the thermal stresses around a radioactive waste depository in hard rock

    International Nuclear Information System (INIS)

    Hodgkinson, D.P.; Bourke, P.J.

    1980-01-01

    The disposal of heat emitting radioactive waste into hard rock should result in temperature rises and thermal gradients over distances of several hundred metres for several centuries. The consequent constrained thermal expansion of the rock would induce stresses which have important implications for possible water-borne leakage of radionuclides and for depository design. These problems are assessed by considering a simplified mathematical model for which analytic solutions to the temperature and stress fields are derived. (author)

  10. Thermal stress microfracturing of crystalline and sedimentary rock. Final report, September 16, 1987--September 15, 1991

    International Nuclear Information System (INIS)

    Wang, H.

    1995-08-01

    Slow uniform heating of crustal rocks is both a pervasive geologic process and an anticipated by-product of radioactive waste disposal. Such heating generates microcracks which alter the strength, elastic moduli, and transport properties of the rock. The research program was to understand mechanisms of thermal cracking in rocks. It included development of a theoretical understanding of cracking due to thermal stresses, laboratory work to characterize crack strain in rocks thermally stressed under different conditions (including natural thermal histories), microscopic work to count and catalog crack occurrences, and geologic application to determine paleostress history of granites from the midcontinent

  11. Adaptation to Portuguese of the Depression, Anxiety and Stress Scales (DASS)

    OpenAIRE

    Apóstolo,João Luís Alves; Mendes,Aida Cruz; Azeredo,Zaida Aguiar

    2006-01-01

    Objective: to adapt to Portuguese, of Portugal, the Depression, Anxiety and Stress Scales, a 21-item short scale (DASS 21), designed to measure depression, anxiety and stress. Method: After translation and back-translation with the help of experts, the DASS 21 was administered to patients in external psychiatry consults (N=101), and its internal consistency, construct validity and concurrent validity were measured. Results: The DASS 21 properties certify its quality to measure emotional state...

  12. Modelling and analysis of radial thermal stresses and temperature ...

    African Journals Online (AJOL)

    user

    it acts as an insulating medium and prevents the heat flow, hence the need of providing insulation coating on valves is ... geometry metal components (piston, liner and cylinder head) and found a satisfactory .... model. Step8: Find the radial thermal stress at all the nodal point with the use of temperature ..... Cast iron St. 70.

  13. The stress and stress intensity factors computation by BEM and FEM combination for nozzle junction under pressure and thermal loads

    International Nuclear Information System (INIS)

    Du, Q.; Cen, Z.; Zhu, H.

    1989-01-01

    This paper reports linear elastic fracture analysis based upon the stress intensity factor evaluation successfully applied to safety assessments of cracked structures. The nozzle junction are usually subjected to high pressure and thermal loads simultaneously. In validity of linear elastic fracture analysis, K can be decomposed into K P (caused by mechanic loads) and K τ (caused by thermal loads). Under thermal transient loading, explicit analysis (say by the FEM or BEM) of K tracing an entire history respectively for a range of crack depth may be much more time consuming. The techniques of weight function provide efficient means for transforming the problem into the stress computation of the uncracked structure and generation of influence function (for the given structure and size of crack). In this paper, a combination of BE-FEM has been used for the analysis of the cracked nozzle structure by techniques of weight function. The influence functions are obtained by coupled BE-FEM and the uncracked structure stress are computed by finite element methods

  14. Adaptation au stress hydrique dans le Comahue, en Argentine ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Adaptation au stress hydrique dans le Comahue, en Argentine. On prévoit que les changements climatiques entraîneront une diminution des précipitations annuelles dans le Comahue, une région du centre-ouest de l'Argentine. Conjugué à la hausse prévue de la demande en eau et de l'utilisation de la ressource, ...

  15. Determine variation of poisson ratios and thermal creep stresses and strain rates in an isotropic disc

    Directory of Open Access Journals (Sweden)

    Gupta Nishi

    2016-01-01

    Full Text Available Seth's transition theory is applied to the problem of thermal creep transition stresses and strain rates in a thin rotating disc with shaft having variable density by finite deformation. Neither the yield criterion nor the associated flow rule is assumed here. The results obtained here are applicable to compressible materials. If the additional condition of incompressibility is imposed, then the expression for stresses corresponds to those arising from Tresca yield condition. Thermal effect decreased value of radial stress at the internal surface of the rotating isotropic disc made of compressible material as well as incompressible material and this value of radial stress further much increases with the increase in angular speed. With the introduction of thermal effects, the maximum value of strain rates further increases at the internal surface for compressible materials as compare to incompressible material.

  16. Fibroblast growth factor 21 participates in adaptation to endoplasmic reticulum stress and attenuates obesity-induced hepatic metabolic stress.

    Science.gov (United States)

    Kim, Seong Hun; Kim, Kook Hwan; Kim, Hyoung-Kyu; Kim, Mi-Jeong; Back, Sung Hoon; Konishi, Morichika; Itoh, Nobuyuki; Lee, Myung-Shik

    2015-04-01

    Fibroblast growth factor 21 (FGF21) is an endocrine hormone that exhibits anti-diabetic and anti-obesity activity. FGF21 expression is increased in patients with and mouse models of obesity or nonalcoholic fatty liver disease (NAFLD). However, the functional role and molecular mechanism of FGF21 induction in obesity or NAFLD are not clear. As endoplasmic reticulum (ER) stress is triggered in obesity and NAFLD, we investigated whether ER stress affects FGF21 expression or whether FGF21 induction acts as a mechanism of the unfolded protein response (UPR) adaptation to ER stress induced by chemical stressors or obesity. Hepatocytes or mouse embryonic fibroblasts deficient in UPR signalling pathways and liver-specific eIF2α mutant mice were employed to investigate the in vitro and in vivo effects of ER stress on FGF21 expression, respectively. The in vivo importance of FGF21 induction by ER stress and obesity was determined using inducible Fgf21-transgenic mice and Fgf21-null mice with or without leptin deficiency. We found that ER stressors induced FGF21 expression, which was dependent on a PKR-like ER kinase-eukaryotic translation factor 2α-activating transcription factor 4 pathway both in vitro and in vivo. Fgf21-null mice exhibited increased expression of ER stress marker genes and augmented hepatic lipid accumulation after tunicamycin treatment. However, these changes were attenuated in inducible Fgf21-transgenic mice. We also observed that Fgf21-null mice with leptin deficiency displayed increased hepatic ER stress response and liver injury, accompanied by deteriorated metabolic variables. Our results suggest that FGF21 plays an important role in the adaptive response to ER stress- or obesity-induced hepatic metabolic stress.

  17. Thermal adaptation and phenotypic plasticity in a warming world: Insights from common garden experiments on Alaskan sockeye salmon

    Science.gov (United States)

    Sparks, Morgan M.; Westley, Peter A. H.; Falke, Jeffrey A.; Quinn, Thomas P.

    2017-01-01

    An important unresolved question is how populations of coldwater-dependent fishes will respond to rapidly warming water temperatures. For example, the culturally and economically important group, Pacific salmon (Oncorhynchus spp.), experience site-specific thermal regimes during early development that could be disrupted by warming. To test for thermal local adaptation and heritable phenotypic plasticity in Pacific salmon embryos, we measured the developmental rate, survival, and body size at hatching in two populations of sockeye salmon (Oncorhynchus nerka) that overlap in timing of spawning but incubate in contrasting natural thermal regimes. Using a split half-sibling design, we exposed embryos of 10 families from each of two populations to variable and constant thermal regimes. These represented both experienced temperatures by each population, and predicted temperatures under plausible future conditions based on a warming scenario from the downscaled global climate model (MIROC A1B scenario). We did not find evidence of thermal local adaptation during the embryonic stage for developmental rate or survival. Within treatments, populations hatched within 1 day of each other, on average, and amongtreatments, did not differ in survival in response to temperature. We did detect plasticity to temperature; embryos developed 2.5 times longer (189 days) in the coolest regime compared to the warmest regime (74 days). We also detected variation in developmental rates among families within and among temperature regimes, indicating heritable plasticity. Families exhibited a strong positive relationship between thermal variability and phenotypic variability in developmental rate but body length and mass at hatching were largely insensitive to temperature. Overall, our results indicated a lack of thermal local adaptation, but a presence of plasticity in populations experiencing contrasting conditions, as well as family-specific heritable plasticity that could

  18. Transient thermal stresses in a circular cylinder with constrained ends

    International Nuclear Information System (INIS)

    Goshima, Takahito; Miyao, Kaju

    1986-01-01

    This paker deals with the transient thermal stresses in a finite circular cylinder constrained at both end surfaces and subjected to axisymmetric temperature distribution on the lateral surface. The thermoelastic problem is formulated in terms of a thermoelastic displacement potential and three harmonic stress functions. Numerical calculations are carried out for the case of the uniform temperature distribution on the lateral surface. The stress distributions on the constrained end and the free suface are shown graphically, and the singularity in stresses appearing at the circumferencial edge is considered. Moreover, the approximate solution based upon the plane strain theory is introduced in order to compare the rigorous one, and it is considered how the length of the cylinder and the time proceeds affect on the accuracy of the approximation. (author)

  19. Thermal and stress analysis of a fuel rod research project 277

    International Nuclear Information System (INIS)

    1975-04-01

    The purpose of this investigation was to perform an analytical evaluation of a postulated loss of coolant incident in a large pressurized water reactor. A coupled thermal and stress finite element analysis of a fuel rod subjected to a hypothetical blow-down transient was carried out. The effect of two gap conditions and two initial stress states on the response of the fuel rod was studied. Both one-dimensional and three-dimensional models were investigated. To study the heat transfer in the gap region one assumes a conductive mode of heat transfer in the gap characterized by an equivalent thermal conductivity, which is dependent on the current gap width. Accordingly, coupled analysis procedure and computational scheme were established. A mesh generation computer program was developed for the three-dimensional model

  20. Design of an RF window for L-band CW klystron based on thermal-stress analysis

    International Nuclear Information System (INIS)

    Yamaguchi, Seiya; Sato, Isamu; Konashi, Kenji; Ohshika, Junji.

    1993-01-01

    Design of klystron RF window has been performed based on a thermal-stress analysis for L-band CW electron linac for nuclear wastes transmutation. It was shown that the hoop stress for a modified disk is 46% of that of normal disk. Thermal load test has been done which indicated that the modified disk is proof against power twice as much as that for the normal disk. (author)

  1. Bandgap tuning with thermal residual stresses induced in a quantum dot.

    Science.gov (United States)

    Kong, Eui-Hyun; Joo, Soo-Hyun; Park, Hyun-Jin; Song, Seungwoo; Chang, Yong-June; Kim, Hyoung Seop; Jang, Hyun Myung

    2014-09-24

    Lattice distortion induced by residual stresses can alter electronic and mechanical properties of materials significantly. Herein, a novel way of the bandgap tuning in a quantum dot (QD) by lattice distortion is presented using 4-nm-sized CdS QDs grown on a TiO2 particle as an application example. The bandgap tuning (from 2.74 eV to 2.49 eV) of a CdS QD is achieved by suitably adjusting the degree of lattice distortion in a QD via the tensile residual stresses which arise from the difference in thermal expansion coefficients between CdS and TiO2. The idea of bandgap tuning is then applied to QD-sensitized solar cells, achieving ≈60% increase in the power conversion efficiency by controlling the degree of thermal residual stress. Since the present methodology is not limited to a specific QD system, it will potentially pave a way to unexplored quantum effects in various QD-based applications. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  2. Numerical Analysis of Thermal Stresses around Fasteners in Composite Metal Foils

    Science.gov (United States)

    Nammi, S. K.; Butt, J.; –L Mauricette, J.; Shirvani, H.

    2017-12-01

    The process of composite metal foil manufacturing (CMFM) has reduced a number of limitations associated with commercial additive manufacturing (AM) methods. The existing metal AM machines are restricted by their build envelope and there is a growing market for the manufacture of large parts using AM. These parts are subsequently manufactured in fragments and are fastened together. This paper analyses the thermal stresses around cylindrical fasteners for three layered metal composite parts consisting of aluminium foil, brazing paste and copper foil layers. The investigation aims to examine the mechanical integrity of the metallurgically bonded aluminium/copper foils of 100 micron thickness manufactured in a disc shape. A cylindrical fastener set at an elevated temperature of 100 °C is fitted in the middle of the disc which results in a steady-state thermal distribution. Radial and shear stresses are computed using finite element method which shows that non-zero shear stresses developed by the copper layer inhibit the axial slippage of the fastener and thereby establishing the suitability of rivet joints for CMFM parts.

  3. Perturbation of baseline thermal stress in the Mound 9516 Shipping Package primary containment vessel

    International Nuclear Information System (INIS)

    Sansalone, K.H.F.

    1995-01-01

    Full-capacity loading of heat sources into the Mound 9516 Shipping Package primary containment vessel (PCV) results in temperature gradients which are symmetric, due to the axisymmetry of the package design. Concern over the change in thermal gradients (and therefore, stress) in the PCV due to sub-capacity loading led to the analytical examination of this phenomenon. The PCVs are cylindrical in shape and are loaded into the package such that they and all containment components are concentrically arranged along a common longitudinal axis. If the design full-capacity loading of the PCVs in this package assumes the axisymmetric (or more precisely, cyclicly symmetric) arrangement of its heat-producing contents, then sub-capacity loading implies that in many cases, the load arrangement could be asymmetric with respect to the longitudinal axis. It is then feasible that the departure from heat load axisymmetry could perturb the nominal thermal gradients so that thermally-induced stress within the PCV might increase to levels deemed unacceptable. This study applies Finite Element analysis (FEA) to the problem and demonstrates that no such unacceptable thermal stress increase occurs in the PCV material due to the asymmetric arrangement of contents. copyright 1995 American Institute of Physics

  4. Local adaptation to altitude underlies divergent thermal physiology in tropical killifishes of the genus Aphyosemion.

    Directory of Open Access Journals (Sweden)

    David J McKenzie

    Full Text Available In watersheds of equatorial West Africa, monophyletic groups of killifish species (genus Aphyosemion occur in discrete altitudinal ranges, low altitude species (LA, sea level to ∼350 m or high altitude species (HA, 350 to 900 m. We investigated the hypothesis that local adaptation to altitude by the LA and HA species would be revealed as divergent effects of temperature on their physiological energetics. Two species from each group (mass ∼350 mg were acclimated to 19, 25 and 28°C, with 19 and 28°C estimated to be outside the thermal envelope for LA or HA, respectively, in the wild. Wild-caught animals (F0 generation were compared with animals raised in captivity at 25°C (F1 generation to investigate the contribution of adaptation versus plasticity. Temperature significantly increased routine metabolic rate in all groups and generations. However, LA and HA species differed in the effects of temperature on their ability to process a meal. At 25°C, the specific dynamic action (SDA response was completed within 8 h in all groups, but acclimation to temperatures beyond the thermal envelope caused profound declines in SDA performance. At 19°C, the LA required ∼14 h to complete the SDA, whereas the HA required only ∼7 h. The opposite effect was observed at 28°C. This effect was evident in both F0 and F1. Reaction norms for effects of temperature on SDA therefore revealed a trade-off, with superior performance at warmer temperatures by LA being associated with inferior performance at cooler temperatures, and vice-versa in HA. The data indicate that divergent physiological responses to temperature in the LA and HA species reflect local adaptation to the thermal regime in their habitat, and that local adaptation to one thermal environment trades off against performance in another.

  5. Transient thermal stresses in circular cylinder under intermittently sudden heat generation

    International Nuclear Information System (INIS)

    Sugano, Y.; Saito, K.; Takeuti, Y.

    1975-01-01

    The thermal stresses associated with the transient temperature distribution arising in a circular cylinder under intermittently changing sudden heat generation over a finite band and with heat loss to a surrounding medium on the remainder of the cylinder surface are exactly analysed. For the first time the temperature field in a circular cylinder under sudden heat generation over a finite band of the cylinder surface is determined by combined use of Fourier cosine, Laplace transforms in axial position and time, respectively. Secondly it is assumed that the temperature fields in a circular cylinder subjected to heat generation Qsub(i) (i=0, 1, 2, ...) independently over a finite band are given by T 0 (r,z,t), T 1 (r,z,t), T 2 (r,z,t),... respectively. Tsub(i)(r,z,t) indicates the temperature field before the i-th heat generation Qsub(i). The thermal stresses associated with the temperature field described above are analysed by using the Hoyle stress functions. Numerical calculations are carried out for the extensive case of the ratio of the heat-generating length to the diameter of cylinder. It is found that the time in which the maximum stresses occur on the cylinder surface does not depend on the heat-generating length-to-diameter ratio

  6. Ploidy plasticity: a rapid and reversible strategy for adaptation to stress.

    Science.gov (United States)

    Berman, Judith

    2016-05-01

    Organisms must be able to grow in a broad range of conditions found in their normal growth environment and for a species to survive, at least some cells in a population must adapt rapidly to extreme stress conditions that kill the majority of cells.Candida albicans, the most prevalent fungal pathogen of humans resides as a commensal in a broad range of niches within the human host. Growth conditions in these niches are highly variable and stresses such exposure to antifungal drugs can inhibit population growth abruptly. One of the mechanisms C. albicans uses to adapt rapidly to severe stresses is aneuploidy-a change in the total number of chromosomes such that one or more chromosomes are present in excess or are missing. Aneuploidy is quite common in wild isolates of fungi and other eukaryotic microbes. Aneuploidy can be achieved by chromosome nondisjunction during a simple mitosis, and in stress conditions it begins to appear after two mitotic divisions via a tetraploid intermediate. Aneuploidy usually resolves to euploidy (a balanced number of chromosomes), but not necessarily to diploidy. Aneuploidy of a specific chromosome can confer new phenotypes by virtue of the copy number of specific genes on that chromosome relative to the copies of other genes. Thus, it is not aneuploidy per se, but the relative copy number of specific genes that confers many tested aneuploidy-associated phenotypes. Aneuploidy almost always carries a fitness cost, as cells express most proteins encoded by genes on the aneuploid chromosome in proportion to the number of DNA copies of the gene. This is thought to be due to imbalances in the stoichiometry of different components of large complexes. Despite this, fitness is a relative function-and if stress is severe and population growth has slowed considerably, then even small growth advantages of some aneuploidies can provide a selective advantage. Thus, aneuploidy appears to provide a transient solution to severe and sudden stress

  7. Cemented carbide cutting tool: Laser processing and thermal stress analysis

    Energy Technology Data Exchange (ETDEWEB)

    Yilbas, B.S. [Mechanical Engineering Department, KFUPM, Box 1913, Dhahran 31261 (Saudi Arabia)]. E-mail: bsyilbas@kfupm.edu.sa; Arif, A.F.M. [Mechanical Engineering Department, KFUPM, Box 1913, Dhahran 31261 (Saudi Arabia); Karatas, C. [Engineering Faculty, Hacettepe University, Ankara (Turkey); Ahsan, M. [Mechanical Engineering Department, KFUPM, Box 1913, Dhahran 31261 (Saudi Arabia)

    2007-04-15

    Laser treatment of cemented carbide tool surface consisting of W, C, TiC, TaC is examined and thermal stress developed due to temperature gradients in the laser treated region is predicted numerically. Temperature rise in the substrate material is computed numerically using the Fourier heating model. Experiment is carried out to treat the tool surfaces using a CO{sub 2} laser while SEM, XRD and EDS are carried out for morphological and structural characterization of the treated surface. Laser parameters were selected include the laser output power, duty cycle, assisting gas pressure, scanning speed, and nominal focus setting of the focusing lens. It is found that temperature gradient attains significantly high values below the surface particularly for titanium and tantalum carbides, which in turn, results in high thermal stress generation in this region. SEM examination of laser treated surface and its cross section reveals that crack initiation below the surface occurs and crack extends over the depth of the laser treated region.

  8. Simulasi Thermal Stress Pada Tube Superheater Package Boiler

    OpenAIRE

    Hamdani

    2013-01-01

    This project investigates the thermal stress behavior and the mechanisms of superheater tube failure with experimental method and numerical analysis. First of all the procedures for failure analysis were applied to determine the root cause of them. A visual assessment of boiler critical pressure parts was carried out, and then the failed tube is examined by nondestructive evaluation. For the numerical domain, initially the elastic solution for a superheater tube subjected to an internal press...

  9. Effect of the Modification of the Start-Up Sequence on the Thermal Stresses for a Microgas Turbine

    Directory of Open Access Journals (Sweden)

    Oscar Tenango-Pirin

    2016-01-01

    Full Text Available Microgas turbines (MGT are an alternative for small-scale energy production; however, their small size becomes a drawback since it enhances the heat transfer among their components. Moreover, heat transfer drives to temperature gradients which become higher during transient cycles like start-up. The influence of different start-up curves on temperature and thermal stresses of a microgas turbine was investigated. Stationary and rotational blades of the turbine were numerically simulated using CFD and FEM commercial codes. Conjugated heat transfer cases were solved for obtaining heat transfer from fluid toward the blades. Changes of temperature gradients within the blades during the start-ups were calculated under transient state with boundary conditions according to each curve to assess accurate thermal stresses calculations. Results showed that the modification of the start-up curves had an impact on the thermal stresses levels and on the time when highest stresses appeared on each component. Furthermore, zones highly stressed were located near the constraints of blades where thermal strains are restricted. It was also found that the curve that had a warming period at the beginning of the start-up allowed reducing the peaks of stresses making it more feasible and safer for the turbine start-up operation.

  10. Characterisation of the transcriptomes of genetically diverse Listeria monocytogenes exposed to hyperosmotic and low temperature conditions reveal global stress-adaptation mechanisms.

    Directory of Open Access Journals (Sweden)

    Juliana Durack

    Full Text Available The ability of Listeria monocytogenes to adapt to various food and food- processing environments has been attributed to its robustness, persistence and prevalence in the food supply chain. To improve the present understanding of molecular mechanisms involved in hyperosmotic and low-temperature stress adaptation of L. monocytogenes, we undertook transcriptomics analysis on three strains adapted to sub-lethal levels of these stress stimuli and assessed functional gene response. Adaptation to hyperosmotic and cold-temperature stress has revealed many parallels in terms of gene expression profiles in strains possessing different levels of stress tolerance. Gene sets associated with ribosomes and translation, transcription, cell division as well as fatty acid biosynthesis and peptide transport showed activation in cells adapted to either cold or hyperosmotic stress. Repression of genes associated with carbohydrate metabolism and transport as well as flagella was evident in stressed cells, likely linked to activation of CodY regulon and consequential cellular energy conservation.

  11. Laser-induced cracks in ice due to temperature gradient and thermal stress

    Science.gov (United States)

    Yang, Song; Yang, Ying-Ying; Zhang, Jing-Yuan; Zhang, Zhi-Yan; Zhang, Ling; Lin, Xue-Chun

    2018-06-01

    This work presents the experimental and theoretical investigations on the mechanism of laser-induce cracks in ice. The laser-induced thermal gradient would generate significant thermal stress and lead to the cracking without thermal melting in the ice. The crack density induced by a pulsed laser in the ice critically depends on the laser scanning speed and the size of the laser spot on the surface, which determines the laser power density on the surface. A maximum of 16 cracks within an area of 17 cm × 10 cm can be generated when the laser scanning speed is at 10 mm/s and the focal point of the laser is right on the surface of the ice with a laser intensity of ∼4.6 × 107 W/cm2. By comparing the infrared images of the ice generated at various experimental conditions, it was found that a larger temperature gradient would result in more laser-induced cracks, while there is no visible melting of the ice by the laser beam. The data confirm that the laser-induced thermal stress is the main cause of the cracks created in the ice.

  12. Plasticity and stress tolerance override local adaptation in the responses of Mediterranean holm oak seedlings to drought and cold.

    Science.gov (United States)

    Gimeno, Teresa E; Pías, Beatriz; Lemos-Filho, José P; Valladares, Fernando

    2009-01-01

    Plant populations of widely distributed species experience a broad range of environmental conditions that can be faced by phenotypic plasticity or ecotypic differentiation and local adaptation. The strategy chosen will determine a population's ability to respond to climate change. To explore this, we grew Quercus ilex (L.) seedlings from acorns collected at six selected populations from climatically contrasting localities and evaluated their response to drought and late season cold events. Maximum photosynthetic rate (A(max)), instantaneous water use efficiency (iWUE), and thermal tolerance to freeze and heat (estimated from chlorophyll fluorescence versus temperature curves) were measured in 5-month-old seedlings in control (no stress), drought (water-stressed), and cold (low suboptimal temperature) conditions. The observed responses were similar for the six populations: drought decreased A(max) and increased iWUE, and cold reduced A(max) and iWUE. All the seedlings maintained photosynthetic activity under adverse conditions (drought and cold), and rapidly increased their iWUE by closing stomata when exposed to drought. Heat and freeze tolerances were similarly high for seedlings from all the populations, and they were significantly increased by drought and cold, respectively; and were positively related to each other. Differences in seedling performance across populations were primarily induced by maternal effects mediated by seed size and to a lesser extent by idiosyncratic physiologic responses to drought and low temperatures. Tolerance to multiple stresses together with the capacity to physiologically acclimate to heat waves and cold snaps may allow Q. ilex to cope with the increasingly stressful conditions imposed by climate change. Lack of evidence of physiologic seedling adaptation to local climate may reflect opposing selection pressures to complex, multidimensional environmental conditions operating within the distribution range of this species.

  13. A study on thermal residual stresses in the matrix and fiber of a misoriented short fiber composite

    International Nuclear Information System (INIS)

    Son, Bong Jin; Lee, Joon Hyun

    1994-01-01

    An elastic model is developed to predict the average thermal residual stresses in the matrix and fiber of a misoriented short fiber composite. The thermal residual stresses are induced by the mismatch in the coefficient of the thermal expansion of the matrix and fiber when the composite is subjected to a uniform temperature change. The model considers two special cases of fiber misorientation; two-dimensional in-plane and three-dimensional axisymmetric. The analytical formulation of the model is based on Eshelby's equivalent inclusion method and is unique in that it is able to account for interactions among fibers. The model is more general than past models and it is able to treat prior analyses of the simpler composite systems as extream cases. The present model is to investigate the effects of fiber volume fraction, distribution type, distribution cut-off angle, and aspect ratio on thermal residual stress for both in-plane and axisymmetric fiber misorientation. Fiber volume fraction, aspect ratio, and disturbution cut-off angle are shown to have more significant effects on the magnitude of the thermal residual stresses than fiber distrubution type for both in-plane and axisymmetric misorientation.

  14. Heat Transfer and Thermal Stress Analysis of a Mandibular Molar Tooth Restored by Different Indirect Restorations Using a Three-Dimensional Finite Element Method.

    Science.gov (United States)

    Çelik Köycü, Berrak; İmirzalıoğlu, Pervin

    2017-07-01

    Daily consumption of food and drink creates rapid temperature changes in the oral cavity. Heat transfer and thermal stress caused by temperature changes in restored teeth may damage the hard and soft tissue components, resulting in restoration failure. This study evaluates the temperature distribution and related thermal stress on mandibular molar teeth restored via three indirect restorations using three-dimensional (3D) finite element analysis (FEA). A 3D finite element model was constructed of a mandibular first molar and included enamel, dentin, pulp, surrounding bone, and indirect class 2 restorations of type 2 dental gold alloy, ceramic, and composite resin. A transient thermal FEA was performed to investigate the temperature distribution and the resulting thermal stress after simulated temperature changes from 36°C to 4 or 60°C for a 2-second time period. The restoration models had similar temperature distributions at 2 seconds in both the thermal conditions. Compared with 60°C exposure, the 4°C condition resulted in thermal stress values of higher magnitudes. At 4ºC, the highest stress value observed was tensile stress (56 to 57 MPa), whereas at 60°C, the highest stress value observed was compressive stress (42 to 43 MPa). These stresses appeared at the cervical region of the lingual enamel. The thermal stress at the restoration surface and resin cement showed decreasing order of magnitude as follows: composite > gold > ceramic, in both thermal conditions. The properties of the restorative materials do not affect temperature distribution at 2 seconds in restored teeth. The pulpal temperature is below the threshold for vital pulp tissue (42ºC). Temperature changes generate maximum thermal stress at the cervical region of the enamel. With the highest thermal expansion coefficient, composite resin restorations exhibit higher stress patterns than ceramic and gold restorations. © 2015 by the American College of Prosthodontists.

  15. THERMAL ADAPTATION, CAMPUS GREENING AND OUTDOOR USE IN LAUTECH CAMPUS, OGBOMOSO, NIGERIA

    Directory of Open Access Journals (Sweden)

    Joseph Adeniran ADEDEJI

    2011-12-01

    Full Text Available The interwoven relationship between the use of indoors and outdoors in the tropics as means of thermal adaptation has long been recognized. In the case of outdoors, this is achieved by green intervention of shading trees as adaptive mechanisms through behavioural thermoregulation. Unfortunately, the indoor academic spaces of LAUTECH campus was not provided with necessary outdoor academic learning environment in the general site planning of the campus for use at peak indoor thermal dissatisfaction period considering the tropical climatic setting of the university. The students’ departmental and faculty associations tried to provide parks for themselves as alternatives which on casual observation are of substandard quality and poorly maintained because of lack of institutional coordination and low funding. This study examined the quality and use of these parks for thermal comfort through behavioral adjustment from subjective field evidence with the goal of improvement. To achieve this, twelve parks were selected within the campus. Questionnaires containing use and quality variables were administered randomly upon 160 users of these parks. The data obtained was subjected to descriptive statistical analysis. Results show that the quality of the parks, weather condition, period of the day, and personal psychological reasons of users has great influence on the use of the parks. The study concludes with policy recommendations on improvement of the quality of the parks and the campus outdoors and greenery in general.

  16. Leuconostoc strains isolated from dairy products: Response against food stress conditions.

    Science.gov (United States)

    D'Angelo, Luisa; Cicotello, Joaquín; Zago, Miriam; Guglielmotti, Daniela; Quiberoni, Andrea; Suárez, Viviana

    2017-09-01

    A systematic study about the intrinsic resistance of 29 strains (26 autochthonous and 3 commercial ones), belonging to Leuconostoc genus, against diverse stress factors (thermal, acidic, alkaline, osmotic and oxidative) commonly present at industrial or conservation processes were evaluated. Exhaustive result processing was made by applying one-way ANOVA, Student's test (t), multivariate analysis by Principal Component Analysis (PCA) and Matrix Hierarchical Cluster Analysis. In addition, heat adaptation on 4 strains carefully selected based on previous data analysis was assayed. The strains revealed wide diversity of resistance to stress factors and, in general, a clear relationship between resistance and Leuconostoc species was established. In this sense, the highest resistance was shown by Leuconostoc lactis followed by Leuconostoc mesenteroides strains, while Leuconostoc pseudomesenteroides and Leuconostoc citreum strains revealed the lowest resistance to the stress factors applied. Heat adaptation improved thermal cell survival and resulted in a cross-resistance against the acidic factor. However, all adapted cells showed diminished their oxidative resistance. According to our knowledge, this is the first study regarding response of Leuconostoc strains against technological stress factors and could establish the basis for the selection of "more robust" strains and propose the possibility of improving their performance during industrial processes. Copyright © 2017 Elsevier Ltd. All rights reserved.

  17. Thermally activated low temperature creep and primary water stress corrosion cracking of NiCrFe alloys

    International Nuclear Information System (INIS)

    Hall, M.M. Jr.

    1993-01-01

    A phenomenological SCC-CGR model is developed based on an apriori assumption that the SCC-CGR is controlled by low temperature creep (LTC). This mode of low temperature time dependent deformation occurs at stress levels above the athermal flow stress by a dislocation glide mechanism that is thermally activated and may be environmentally assisted. The SCC-CGR model equations developed contain thermal activation parameters descriptive of the dislocation creep mechanism. Thermal activation parameters are obtained by fitting the CGR model to SCC-CGR data obtained on Alloy 600 and Alloy X-750. These SCC-CGR activation parameters are compared to LTC activation parameters obtained from stress relaxation tests. When the high concentration of hydrogen at the tip of an SCC crack is considered, the SCC-CGR activation energies and rate sensitivities are shown to be quantitatively consistent with hydrogen reducing the activation energy and increasing the strain rate sensitivity in LTC stress relaxation tests. Stress dependence of SCC-CGR activation energy consistent with that found for the LTC activation energy. Comparisons between temperature dependence of the SCC-CGR stress sensitivity and LTC stress sensitivity provide a basis for speculation on effects of hydrogen and solute carbon on SCC crack growth rates

  18. Temperature-time distribution and thermal stresses on the RTG fins and shell during water cooling

    Science.gov (United States)

    Turner, R. H.

    1983-01-01

    Radioisotope thermoelectric generator (RTG) packages designed for space missions generally do not require active cooling. However, the heat they generate cannot remain inside of the launch vehicle bay and requires active removal. Therefore, before the Shuttle bay door is closed, the RTG coolant tubes attached to the heat rejection fins must be filled with water, which will circulate and remove most of the heat from the cargo bay. There is concern that charging a system at initial temperature around 200 C with water at 24 C can cause unacceptable thermal stresses in the RTG shell and fins. A computer model is developed to estimate the transient temperature distribution resulting from such charging. The thermal stresses resulting from the temperature gradients do not exceed the elastic deformation limit for the material. Since the simplified mathematical model for thermal stresses tends to overestimate stresses, it is concluded that the RTG can be cooled by introducing water at 24 C to the initially hot fin coolant tubes while the RTG is in the Shuttle cargo bay.

  19. Functional evolution of leptin of Ochotona curzoniae in adaptive thermogenesis driven by cold environmental stress.

    Directory of Open Access Journals (Sweden)

    Jie Yang

    Full Text Available BACKGROUND: Environmental stress can accelerate the directional selection and evolutionary rate of specific stress-response proteins to bring about new or altered functions, enhancing an organism's fitness to challenging environments. Plateau pika (Ochotona curzoniae, an endemic and keystone species on Qinghai-Tibetan Plateau, is a high hypoxia and low temperature tolerant mammal with high resting metabolic rate and non-shivering thermogenesis to cope in this harsh plateau environment. Leptin is a key hormone related to how these animals regulate energy homeostasis. Previous molecular evolutionary analysis helped to generate the hypothesis that adaptive evolution of plateau pika leptin may be driven by cold stress. METHODOLOGY/PRINCIPAL FINDINGS: To test the hypothesis, recombinant pika leptin was first purified. The thermogenic characteristics of C57BL/6J mice injected with pika leptin under warm (23±1°C and cold (5±1°C acclimation is investigated. Expression levels of genes regulating adaptive thermogenesis in brown adipose tissue and the hypothalamus are compared between pika leptin and human leptin treatment, suggesting that pika leptin has adaptively and functionally evolved. Our results show that pika leptin regulates energy homeostasis via reduced food intake and increased energy expenditure under both warm and cold conditions. Compared with human leptin, pika leptin demonstrates a superior induced capacity for adaptive thermogenesis, which is reflected in a more enhanced β-oxidation, mitochondrial biogenesis and heat production. Moreover, leptin treatment combined with cold stimulation has a significant synergistic effect on adaptive thermogenesis, more so than is observed with a single cold exposure or single leptin treatment. CONCLUSIONS/SIGNIFICANCE: These findings support the hypothesis that cold stress has driven the functional evolution of plateau pika leptin as an ecological adaptation to the Qinghai-Tibetan Plateau.

  20. Bond strength and stress measurements in thermal barrier coatings

    Energy Technology Data Exchange (ETDEWEB)

    Gell, M.; Jordan, E. [Univ. of Connecticut, Storrs, CT (United States)

    1995-10-01

    Thermal barrier coatings have been used extensively in aircraft gas turbines for more than 15 years to insulate combustors and turbine vanes from the hot gas stream. Plasma sprayed thermal barrier coatings (TBCs) provide metal temperature reductions as much as 300{degrees}F, with improvements in durability of two times or more being achieved. The introduction of TBCs deposited by electron beam physical vapor deposition (EB-PVD) processes in the last five years has provided a major improvement in durability and also enabled TBCs to be applied to turbine blades for improved engine performance. To meet the aggressive Advanced Turbine Systems goals for efficiency, durability and the environment, it will be necessary to employ thermal barrier coatings on turbine airfoils and other hot section components. For The successful application of TBCs to ATS engines with 2600{degrees}F turbine inlet temperatures and required component lives 10 times greater than those for aircraft gas turbine engines, it is necessary to develop quantitative assessment techniques for TBC coating integrity with time and cycles in ATS engines. Thermal barrier coatings in production today consist of a metallic bond coat, such as an MCrAlY overlay coating or a platinum aluminide (Pt-Al) diffusion coating. During heat treatment, both these coatings form a thin, tightly adherent alumina (Al{sub 2}O{sub 3}) film. Failure of TBC coatings in engine service occurs by spallation of the ceramic coating at or near the bond coat to alumina or the alumina to zirconia bonds. Thus, it is the initial strength of these bonds and the stresses at the bond plane, and their changes with engine exposure, that determines coating durability. The purpose of this program is to provide, for the first time, a quantitative assessment of TBC bond strength and bond plane stresses as a function of engine time and cycles.

  1. Thyroid Allostasis–Adaptive Responses of Thyrotropic Feedback Control to Conditions of Strain, Stress, and Developmental Programming

    OpenAIRE

    Apostolos Chatzitomaris; Rudolf Hoermann; John E. Midgley; Steffen Hering; Aline Urban; Barbara Dietrich; Assjana Abood; Harald H. Klein; Harald H. Klein; Johannes W. Dietrich; Johannes W. Dietrich

    2017-01-01

    The hypothalamus–pituitary–thyroid feedback control is a dynamic, adaptive system. In situations of illness and deprivation of energy representing type 1 allostasis, the stress response operates to alter both its set point and peripheral transfer parameters. In contrast, type 2 allostatic load, typically effective in psychosocial stress, pregnancy, metabolic syndrome, and adaptation to cold, produces a nearly opposite phenotype of predictive plasticity. The non-thyroidal illness syndrome (NTI...

  2. Study by X-ray diffraction and mechanical analysis of the residual stress generation during thermal spraying

    International Nuclear Information System (INIS)

    Pina, J.; Dias, A.; Lebrun, J.L.

    2003-01-01

    Thermally sprayed coatings are formed by the deposition of molten or partially molten particles, propelled onto a substrate where they impact, spread and solidify rapidly. Residual stresses are expected within the sprayed deposit as a consequence of the release of thermal and kinetic energies. A wide range of materials and two spraying techniques are considered in this study, namely atmospheric plasma spraying (APS) and high-velocity oxygen fuel. Stresses were determined by the X-ray diffraction (XRD) method. The results were compared with those calculated by mechanical analysis of stress relief in coatings detached from the substrate. Comparison of the results for adherent and free-standing coatings shows that the residual stress state can be resolved in terms of the components suggested by models that propose two stages of stress generation: quenching stresses and secondary-cooling stresses. The in-depth distribution of residual stresses, through the coating thickness, is discussed in terms of the nature of the coating system

  3. Development of residual thermal stress-relieving structure of CFC monoblock target for JT-60SA divertor

    Energy Technology Data Exchange (ETDEWEB)

    Tsuru, Daigo, E-mail: tsuru.daigo@jaea.go.jp; Sakurai, Shinji; Nakamura, Shigetoshi; Ozaki, Hidetsugu; Seki, Yohji; Yokoyama, Kenji; Suzuki, Satoshi

    2015-10-15

    Highlights: • We carried out numerical simulations on residual thermal stress of targets for the JT-60SA divertor. • We developed three measures to reduce residual thermal stress. • We proposed two structures of CFC monoblock target for the JT-60SA divertor. • We confirmed the effectiveness of the structure by infrared thermography inspection and high heat flux test. - Abstract: Carbon fibre-reinforced carbon composite (CFC) monoblock target for JT-60SA divertor is under development towards the mass-production. CFC monoblocks, WCu interlayers and a CuCrZr cooling tube at the centre of the monoblocks were bonded by vacuum brazing in a high temperature, to a target. If residual thermal stress due to difference of thermal expansions between CFC and CuCrZr exceeds the maximum allowable stress of the CFC after the bonding, cracks are generated in the CFC monoblock and heat removal capacity of the target degrades. In this paper, new structures of the targets were proposed, to reduce residual thermal stress and to mitigate the degradation of heat removal capacity of the targets. Some measures, including slitting of the CFC monoblock aside of the cooling tube, replacement of the interlayer material and shifting the position of the cooling tube, were implemented. The effectiveness of the measures was evaluated by numerical simulations. Target mock-ups with the proposed structures were manufactured. Infrared thermography inspection and high heat flux test were carried out on the mock-ups in order to evaluate the heat removal capacity.

  4. In-situ real time measurements of thermal comfort and comparison with the adaptive comfort theory in Dutch residential dwellings

    NARCIS (Netherlands)

    Ioannou, A.; Itard, L.C.M.; Agarwal, Tushar

    2018-01-01

    Indoor thermal comfort is generally assessed using the PMV or the adaptive model. This research presents the results obtained by in-situ real time measurements of thermal comfort and thermal comfort perception in 17 residential dwellings in the Netherlands. The study demonstrates the new

  5. Crop water-stress assessment using an airborne thermal scanner

    Science.gov (United States)

    Millard, J. P.; Jackson, R. D.; Reginato, R. J.; Idso, S. B.; Goettelman, R. C.

    1978-01-01

    An airborne thermal scanner was used to measure the temperature of a wheat crop canopy in Phoenix, Arizona. The results indicate that canopy temperatures acquired about an hour and a half past solar noon were well correlated with presunrise plant water tension, a parameter directly related to plant growth and development. Pseudo-colored thermal images reading directly in stress degree days, a unit indicative of crop irrigation needs and yield potential, were produced. The aircraft data showed significant within-field canopy temperature variability, indicating the superiority of the synoptic view provided by aircraft over localized ground measurements. The standard deviation between airborne and ground-acquired canopy temperatures was 2 C or less.

  6. Proposal on the mitigation methods of thermal stress near the sodium

    International Nuclear Information System (INIS)

    Ando, Masanori; Kasahara, Naoto

    2003-09-01

    A Reactor vessel of fast rector plants contains high temperature liquid sodium in its inside and its upper end is supported by a low temperature structures. Therefore, a significant temperature gradient will arise at the vessel wall near the sodium surface. For this reason, a large thermal stress will be generated around this part. To lower this stress and to protect the vessel, a number of methods have been applied the plants. Generally, these mitigation methods by protection equipments for thermal stress also have some problems such as, increase a mount of materials or to be complicate for control, hard to maintenance and so on. In this research, authors suggested another simple methods for thermal stress, and evaluated their effects using computer analysis. The results obtained in this research are as follows. Authors suggested one method, circulate high temperature gas around outside of the vessel and evaluated the effects of this method by analysis. In case of using this method, Sn (one of index values of design) value might be getting lower about 45%. Authors also suggested another method by setting up a heat transfer plate outside of the vessel and evaluated the effects of this method by analysis. Effects of this method depend on material of the plate. In case of using Carbon as material of plate, Sn value might be 27% lower and in case of using 12Cr steel as material of plate, Sn value might be 15% lower. Authors also suggested another method by changing material of the guard vessel to be the one which has good ability of heat transfer and evaluated the effects of this method by analysis. In case of changing material of guard vessel to 12Cr steel, Sn value might be lower about 12%. (author)

  7. Investigations on the effect of creep stress on the thermal properties of metallic materials

    International Nuclear Information System (INIS)

    Radtke, U.; Crostack, H.A.; Winschuh, E.

    1995-01-01

    Using thermal wave analysis with front side infrared detection on sample material damaged by creep, one examines whether the creep stress has an effect on the thermal material properties and to what effect this can be used to estimate the remaining service life. (orig.) [de

  8. Evaluation of common bean (Phaseolus vulgaris L. genotypes for drought stress adaptation in Ethiopia

    Directory of Open Access Journals (Sweden)

    Kwabena Darkwa

    2016-10-01

    Full Text Available Drought stress linked with climate change is one of the major constraints faced by common bean farmers in Africa and elsewhere. Mitigating this constraint requires the selection of resilient varieties that withstand drought threats to common bean production. This study assessed the drought response of 64 small red-seeded genotypes of common bean grown in a lattice design replicated twice under contrasting moisture regimes, terminal drought stress and non-stress, in Ethiopia during the dry season from November 2014 to March 2015. Multiple plant traits associated with drought were assessed for their contribution to drought adaptation of the genotypes. Drought stress determined by a drought intensity index was moderate (0.3. All the assessed traits showed significantly different genotypic responses under drought stress and non-stress conditions. Eleven genotypes significantly (P ≤ 0.05 outperformed the drought check cultivar under both drought stress and non-stress conditions in seed yielding potential. Seed yield showed positive and significant correlations with chlorophyll meter reading, vertical root pulling resistance force, number of pods per plant, and seeds per pod under both soil moisture regimes, indicating their potential use in selection of genotypes yielding well under drought stress and non-stress conditions. Clustering analysis using Mahalanobis distance grouped the genotypes into four groups showing high and significant inter-cluster distance, suggesting that hybridization between drought-adapted parents from the groups will provide the maximum genetic recombination for drought tolerance in subsequent generations.

  9. Hepatic ZIP14-mediated zinc transport is required for adaptation to endoplasmic reticulum stress.

    Science.gov (United States)

    Kim, Min-Hyun; Aydemir, Tolunay B; Kim, Jinhee; Cousins, Robert J

    2017-07-18

    Extensive endoplasmic reticulum (ER) stress damages the liver, causing apoptosis and steatosis despite the activation of the unfolded protein response (UPR). Restriction of zinc from cells can induce ER stress, indicating that zinc is essential to maintain normal ER function. However, a role for zinc during hepatic ER stress is largely unknown despite important roles in metabolic disorders, including obesity and nonalcoholic liver disease. We have explored a role for the metal transporter ZIP14 during pharmacologically and high-fat diet-induced ER stress using Zip14 -/- (KO) mice, which exhibit impaired hepatic zinc uptake. Here, we report that ZIP14-mediated hepatic zinc uptake is critical for adaptation to ER stress, preventing sustained apoptosis and steatosis. Impaired hepatic zinc uptake in Zip14 KO mice during ER stress coincides with greater expression of proapoptotic proteins. ER stress-induced Zip14 KO mice show greater levels of hepatic steatosis due to higher expression of genes involved in de novo fatty acid synthesis, which are suppressed in ER stress-induced WT mice. During ER stress, the UPR-activated transcription factors ATF4 and ATF6α transcriptionally up-regulate Zip14 expression. We propose ZIP14 mediates zinc transport into hepatocytes to inhibit protein-tyrosine phosphatase 1B (PTP1B) activity, which acts to suppress apoptosis and steatosis associated with hepatic ER stress. Zip14 KO mice showed greater hepatic PTP1B activity during ER stress. These results show the importance of zinc trafficking and functional ZIP14 transporter activity for adaptation to ER stress associated with chronic metabolic disorders.

  10. Theoretical basis for a transient thermal elastic-plastic stress analysis of nuclear reactor fuel elements

    International Nuclear Information System (INIS)

    Hsu, T.R.; Bertels, A.W.M.; Banerjee, S.; Harrison, W.C.

    1976-07-01

    This report presents the theoretical basis for a transient thermal elastic-plastic stress analysis of a nuclear reactor fuel element subject to severe transient thermo-mechanical loading. A finite element formulation is used for both the non-linear stress analysis and thermal analysis. These two major components are linked together to form an integrated program capable of predicting fuel element transient behaviour in two dimensions. Specific case studies are presented to illustrate capabilities of the analysis. (author)

  11. Relative Quantitative Proteomic Analysis of Brucella abortus Reveals Metabolic Adaptation to Multiple Environmental Stresses.

    Science.gov (United States)

    Zai, Xiaodong; Yang, Qiaoling; Yin, Ying; Li, Ruihua; Qian, Mengying; Zhao, Taoran; Li, Yaohui; Zhang, Jun; Fu, Ling; Xu, Junjie; Chen, Wei

    2017-01-01

    Brucella spp. are facultative intracellular pathogens that cause chronic brucellosis in humans and animals. The virulence of Brucella primarily depends on its successful survival and replication in host cells. During invasion of the host tissue, Brucella is simultaneously subjected to a variety of harsh conditions, including nutrient limitation, low pH, antimicrobial defenses, and extreme levels of reactive oxygen species (ROS) via the host immune response. This suggests that Brucella may be able to regulate its metabolic adaptation in response to the distinct stresses encountered during its intracellular infection of the host. An investigation into the differential proteome expression patterns of Brucella grown under the relevant stress conditions may contribute toward a better understanding of its pathogenesis and adaptive response. Here, we utilized a mass spectrometry-based label-free relative quantitative proteomics approach to investigate and compare global proteomic changes in B. abortus in response to eight different stress treatments. The 3 h short-term in vitro single-stress and multi-stress conditions mimicked the in vivo conditions of B. abortus under intracellular infection, with survival rates ranging from 3.17 to 73.17%. The proteomic analysis identified and quantified a total of 2,272 proteins and 74% of the theoretical proteome, thereby providing wide coverage of the B. abortus proteome. By including eight distinct growth conditions and comparing these with a control condition, we identified a total of 1,221 differentially expressed proteins (DEPs) that were significantly changed under the stress treatments. Pathway analysis revealed that most of the proteins were involved in oxidative phosphorylation, ABC transporters, two-component systems, biosynthesis of secondary metabolites, the citrate cycle, thiamine metabolism, and nitrogen metabolism; constituting major response mechanisms toward the reconstruction of cellular homeostasis and metabolic

  12. Cytosolic phosphoenolpyruvate carboxykinase is a response gene involved in porcine adipocyte adaptation to heat stress.

    Science.gov (United States)

    Qu, Huan; Ajuwon, Kolapo M

    2018-05-04

    Heat stress (HS) leads to increased lipid storage and expression of cytosolic phosphoenolpyruvate carboxykinase (PCK1) in pig adipocytes. However, the importance of PCK1 activation and lipid storage in the adaptive response to HS is unknown. Therefore, in vitro experiments were conducted to investigate the effect of PCK1 inhibition with 3-mercaptopicolinic acid (3MPA) on lipid storage and adipocyte response during HS. In vitro culture of adipocytes under HS (41.0 °C) increased (P cultured adipocytes were less able to induce adaptive responses such as upregulation of HSP70 and triglycerides, and this exacerbated ER stress during HS. Thus, PCK1 may function to alleviate ER stress that occurs during HS.

  13. Quantifying Cyclic Thermal Stresses Due to Solar Exposure in Rock Fragments in Gale Crater, Mars

    Science.gov (United States)

    Hallet, B.; Mackenzie-Helnwein, P.; Sletten, R. S.

    2017-12-01

    Curiosity and earlier rovers on Mars have revealed in detail rocky landscapes with decaying outcrops, rubble, stone-littered regolith, and bedrock exposures that reflect the weathering processes operating on rock exposed to Mars' cold and hyperarid environment. Evidence from diverse sources points to the importance of thermal stresses driven by cyclic solar exposure in contributing to the mechanical weathering of exposed rock and generation of regolith in various settings on Earth [1,2,3], and even more so on extraterrestrial bodies where large, rapid cyclic temperature variations are frequent (e.g. Mars [4], as well as comets [5], asteroids [6] and other airless bodies [7]). To study these thermal stresses, we use a 3d finite element (FE) model constrained by ground-based surface temperature measurements from Curiosity's Environmental Monitoring Station (REMS). The numerical model couples radiation and conduction with elastic response to determine the temperature and stress fields in individual rocks on the surface of Mars based on rock size and thermo-mechanical properties. We provide specific quantitative results for boulder-size basalt rocks resting on the ground using a realistic thermal forcing that closely matches the REMS temperature observations, and related thermal inertia data. Moreover, we introduce analytical studies showing that these numerical results can readily be generalized. They are quite universal, informing us about thermal stresses due to cyclic solar exposure in general, for rock fragments of different sizes, lithologies, and fracture- thermal- and mechanical-properties. Using Earth-analogue studies to gain insight, we also consider how the shapes, fractures, and surface details of rock fragments imaged by Curiosity likely reflect the importance of rock breakdown due to thermal stresses relative to wind-driven rock erosion and other surface processes on Mars. References:[1] McFadden L et al. (2005) Geol. Soc.Am. Bull. 117(1-2): 161-173 [2

  14. Qinshan phase II extension nuclear power project thermal stratification and fatigue stress analysis for pressurizer surge line

    International Nuclear Information System (INIS)

    Yu Xiaofei; Zhang Yixiong; Ai Honglei

    2010-01-01

    Thermal stratification of pressurizer surge line induced by the inside fluid brings on global bending moments, local thermal stresses, unexpected displacements and support loadings of the pipe system. In order to avoid a costly three-dimensional computation, a combined 1D/2D technique has been developed and implemented to analyze the thermal stratification and fatigue stress of pressurize surge line of QINSHAN Phase II Extension Nuclear Power Project in this paper, using the computer codes SYSTUS and ROCOCO. According to the mechanical analysis results of stratification, the maximum stress and cumulative usage factor, the loadings at connections of surge line to main pipe and RCP and the displacements of surge line at supports are obtained. (authors)

  15. A prediction method of temperature distribution and thermal stress for the throttle turbine rotor and its application

    Directory of Open Access Journals (Sweden)

    Yang Yu

    2017-01-01

    Full Text Available In this paper, a prediction method of the temperature distribution for the thermal stress for the throttle-regulated steam turbine rotor is proposed. The rotor thermal stress curve can be calculated according to the preset power requirement, the operation mode and the predicted critical parameters. The results of the 660 MW throttle turbine rotor show that the operators are able to predict the operation results and to adjust the operation parameters in advance with the help of the inertial element method. Meanwhile, it can also raise the operation level, thus providing the technical guarantee for the thermal stress optimization control and the safety of the steam turbine rotor under the variable load operation.

  16. Central neuropeptide Y plays an important role in mediating the adaptation mechanism against chronic stress in male rats.

    Science.gov (United States)

    Yang, Yu; Babygirija, Reji; Zheng, Jun; Shi, Bei; Sun, Weinan; Zheng, Xiaojiao; Zhang, Fan; Cao, Yu

    2018-02-07

    Exposure to continuous life stress often causes gastrointestinal (GI) symptoms. Studies have shown that neuropeptide Y (NPY) counteracts the biological actions of corticotrophin-releasing factor (CRF), and is involved in the termination of the stress response. However, in chronic repeated restraint stress (CRS) conditions, the actions of NPY on GI motility remain controversial. To evaluate the role of NPY in mediation of the adaptation mechanism and GI motility in CRS conditions, a CRS rat model was set up. Central CRF and NPY expression levels were analyzed, serum corticosterone and NPY concentrations were measured, and GI motor function was evaluated. The NPY Y1 receptor antagonist BIBP-3226 was centrally administered before stress loading, and on days, 1-5, of repeated stress, the central CRF and the serum corticosterone concentrations were measured. In addition, gastric and colonic motor functions were evaluated. The elevated central CRF expression and corticosterone concentration caused by acute stress began to fall after 3 days of stress loading, while central NPY expression and serum NPY began to increase. GI dysmotility also returned to a normal level. Pretreatment with BIBP-3226 abolished the adaptation mechanism, and significantly increased CRF expression and the corticosterone concentration, which resulted in delayed gastric emptying and accelerated fecal pellet output. Inhibited gastric motility and enhanced distal colonic motility were also recorded. CRS-produced adaptation, over-expressed central CRF, and GI dysmotility observed in acute restraint stress were restored to normal levels. Central NPY via the Y1 receptor plays an important role in mediating the adaptation mechanism against chronic stress. Copyright © 2018 Endocrine Society.

  17. X-ray diffraction study of thermally and stress-induced phase transformations in single crystalline Ni-Mn-Ga alloys

    International Nuclear Information System (INIS)

    Martynov, V.V.

    1995-01-01

    Using in-situ single crystal X-ray diffraction methods, thermally- and stress-induced crystal structure evolution was investigated in two Ni-Mn-Ga Heusler-type alloys. For the 51at.%Ni-24at.%Mn-25at.%Ga alloy it was found that application of external stress in a temperature range ∼20 C above the M s at first causes intensity changes of X-ray diffuse scattering peaks in β-phase. Further stressing results in stress-induced phase transformations and under the appropriate conditions three successive martensitic transformations (one is parent-to-martensite and two are martensite-to-martensite transformations) can be stress induced. Of these only the parent-to-martensite transformation can be thermally-induced. Two successive structural transformations (thermally-induced parent-to-martensite and stress-induced martensite-to-martensite transformations) were found in 52at.%Ni-25at.%Mn-23at.%Ga alloy. Crystal structure, lattice parameters, type of modulation, and the length of modulation period for all martensites were identified. (orig.)

  18. Environmental adaptability and stress tolerance of Laribacter hongkongensis: a genome-wide analysis

    Directory of Open Access Journals (Sweden)

    Lau Susanna KP

    2011-06-01

    Full Text Available Abstract Background Laribacter hongkongensis is associated with community-acquired gastroenteritis and traveler's diarrhea and it can reside in human, fish, frogs and water. In this study, we performed an in-depth annotation of the genes in its genome related to adaptation to the various environmental niches. Results L. hongkongensis possessed genes for DNA repair and recombination, basal transcription, alternative σ-factors and 109 putative transcription factors, allowing DNA repair and global changes in gene expression in response to different environmental stresses. For acid stress, it possessed a urease gene cassette and two arc gene clusters. For alkaline stress, it possessed six CDSs for transporters of the monovalent cation/proton antiporter-2 and NhaC Na+:H+ antiporter families. For heavy metals acquisition and tolerance, it possessed CDSs for iron and nickel transport and efflux pumps for other metals. For temperature stress, it possessed genes related to chaperones and chaperonins, heat shock proteins and cold shock proteins. For osmotic stress, 25 CDSs were observed, mostly related to regulators for potassium ion, proline and glutamate transport. For oxidative and UV light stress, genes for oxidant-resistant dehydratase, superoxide scavenging, hydrogen peroxide scavenging, exclusion and export of redox-cycling antibiotics, redox balancing, DNA repair, reduction of disulfide bonds, limitation of iron availability and reduction of iron-sulfur clusters are present. For starvation, it possessed phosphorus and, despite being asaccharolytic, carbon starvation-related CDSs. Conclusions The L. hongkongensis genome possessed a high variety of genes for adaptation to acid, alkaline, temperature, osmotic, oxidative, UV light and starvation stresses and acquisition of and tolerance to heavy metals.

  19. Bioanalytical evidence that chemicals in tattoo ink can induce adaptive stress responses.

    Science.gov (United States)

    Neale, Peta A; Stalter, Daniel; Tang, Janet Y M; Escher, Beate I

    2015-10-15

    Tattooing is becoming increasingly popular, particularly amongst young people. However, tattoo inks contain a complex mixture of chemical impurities that may pose a long-term risk for human health. As a first step towards the risk assessment of these complex mixtures we propose to assess the toxicological hazard potential of tattoo ink chemicals with cell-based bioassays. Targeted modes of toxic action and cellular endpoints included cytotoxicity, genotoxicity and adaptive stress response pathways. The studied tattoo inks, which were extracted with hexane as a proxy for the bioavailable fraction, caused effects in all bioassays, with the red and yellow tattoo inks having the greatest response, particularly inducing genotoxicity and oxidative stress response endpoints. Chemical analysis revealed the presence of polycyclic aromatic hydrocarbons in the tested black tattoo ink at concentrations twice the recommended level. The detected polycyclic aromatic hydrocarbons only explained 0.06% of the oxidative stress response of the black tattoo ink, thus the majority of the effect was caused by unidentified components. The study indicates that currently available tattoo inks contain components that induce adaptive stress response pathways, but to evaluate the risk to human health further work is required to understand the toxicokinetics of tattoo ink chemicals in the body. Copyright © 2015 Elsevier B.V. All rights reserved.

  20. Thermal Stress Analyses for an NLC Positron Target with a 3 mm Spot Radius Beam

    International Nuclear Information System (INIS)

    Stein, W.; Sunwoo, A.; Sheppard, J. C.; Bharadwaj, V.; Schultz, D.

    2002-01-01

    The power deposition of an incident electron beam in a tungsten-rhenium target and the resultant thermal shock stresses in the material have been modeled with a transient, dynamic, structural response finite element code. The Next Linear Collider electron beam is assumed split into three parts, with each part impinging on a 4 radiation lengths thick target. Three targets are required to avoid excessive thermal stresses in the targets. Energy deposition from each beam pulse occurs over 265 nanoseconds and results in heating of the target and pressure pulses straining the material. The rapid power deposition of the electron beam and the resultant temperature profile in the target generates stress and pressure waves in the material that are considerably larger than those calculated by a static analysis. The 6.22 GeV electron beam has a spot radius size of 3 mm and results in a maximum temperature jump of 147 C. Stress pressure pulses are induced in the material from the rapid thermal expansion of the hotter material with peak effective stresses reaching 83 ksi (5.77 x 10 8 Pa) on the back side of the target, which is less than one half of the yield strength of the tungsten/rhenium alloy and below the material fatigue limit

  1. Thermal Stress and Heat Transfer Coefficient for Ceramics Stalk Having Protuberance Dipping into Molten Metal

    Science.gov (United States)

    Noda, Nao-Aki; Hendra; Li, Wenbin; Takase, Yasushi; Ogura, Hiroki; Higashi, Yusuke

    Low pressure die casting is defined as a net shape casting technology in which the molten metal is injected at high speeds and pressure into a metallic die. The low pressure die casting process plays an increasingly important role in the foundry industry as a low-cost and high-efficiency precision forming technique. In the low pressure die casting process is that the permanent die and filling systems are placed over the furnace containing the molten alloy. The filling of the cavity is obtained by forcing the molten metal, by means of a pressurized gas, to rise into a ceramic tube having protuberance, which connects the die to the furnace. The ceramics tube, called stalk, has high temperature resistance and high corrosion resistance. However, attention should be paid to the thermal stress when the stalk having protuberance is dipped into the molten aluminum. It is important to reduce the risk of fracture that may happen due to the thermal stresses. In this paper, thermo-fluid analysis is performed to calculate surface heat transfer coefficient. The finite element method is applied to calculate the thermal stresses when the stalk having protuberance is dipped into the crucible with varying dipping speeds. It is found that the stalk with or without protuberance should be dipped into the crucible slowly to reduce the thermal stress.

  2. A unified momentum equation approach for computing thermal residual stresses during melting and solidification

    Science.gov (United States)

    Yeo, Haram; Ki, Hyungson

    2018-03-01

    In this article, we present a novel numerical method for computing thermal residual stresses from a viewpoint of fluid-structure interaction (FSI). In a thermal processing of a material, residual stresses are developed as the material undergoes melting and solidification, and liquid, solid, and a mixture of liquid and solid (or mushy state) coexist and interact with each other during the process. In order to accurately account for the stress development during phase changes, we derived a unified momentum equation from the momentum equations of incompressible fluids and elastoplastic solids. In this approach, the whole fluid-structure system is treated as a single continuum, and the interaction between fluid and solid phases across the mushy zone is naturally taken into account in a monolithic way. For thermal analysis, an enthalpy-based method was employed. As a numerical example, a two-dimensional laser heating problem was considered, where a carbon steel sheet was heated by a Gaussian laser beam. Momentum and energy equations were discretized on a uniform Cartesian grid in a finite volume framework, and temperature-dependent material properties were used. The austenite-martensite phase transformation of carbon steel was also considered. In this study, the effects of solid strains, fluid flow, mushy zone size, and laser heating time on residual stress formation were investigated.

  3. Stress in piezoelectric hollow sphere with thermal gradient

    International Nuclear Information System (INIS)

    Saadatfar, M.; Rastgoo, A.

    2008-01-01

    The piezoelectric phenomenon has been exploited in science and engineering for decades. Recent advances in smart structures technology have led to a resurgence of interest in piezoelectricity, and in particular, in the solution of fundamental boundary value problems. In this paper, we develop an analytic solution to the axisymmetric problem of a radially polarized, spherically isotropic piezoelectric hollow sphere. The sphere is subjected to uniform internal pressure, or uniform external pressure, or both and thermal gradient. There is a constant thermal difference between its inner and outer surfaces. An analytic solution to the governing equilibrium equations (a coupled system of second-order ordinary differential equations) is obtained. On application of the boundary conditions, the problem is reduced to solving a system of linear algebraic equations. Finally, the stress distributions in the sphere are obtained numerically for two piezoceramics

  4. Investigations on GSK-3β/NF-kB signaling in stress and stress adaptive behavior in electric foot shock subjected mice.

    Science.gov (United States)

    Bali, Anjana; Jaggi, Amteshwar Singh

    2016-04-01

    The present study was designed to explore the role of GSK-3β and NF-kB signaling in electric foot shock-induced stress and stress adaptation. Mice were subjected to foot shocks of 0.5mA intensity and 1s duration of 1h to produce acute stress. Animals were exposed to the same stressor for 5 days to induce stress adaptation. The behavioral alterations were assessed using the actophotometer, hole board, open field and social interaction tests. The serum corticosterone levels were assessed as a marker of the HPA axis. The levels of total GSK-3β, p-GSK-3β-S9 and p-NF-kB were determined in the hippocampus, frontal cortex and amygdala. Acute electric foot shock stress produced behavioral and biochemical changes; decreased the levels of p-GSK-3β-S9, produced no change in total GSK-3β levels and increased p-NF-kB levels in the brain. However, repeated exposure of foot shock stress restored the behavioral and biochemical changes along with normalization of p-GSK-3β-S9 and p-NF-kB levels. Administration of AR-A01, a selective GSK-3β inhibitor, or diethyldithiocarbamic acid (DDTC), a selective NF-kB inhibitor, diminished acute stress-induced behavioral and biochemical changes. Furthermore, AR-A014418 normalized acute stress-induced alterations in p-GSK-3β-S9 and p-NF-kB levels, however, DDTC selectively restored NF-kB levels without any change in p-GSK-3β-S9 levels. It probably suggests that NF-kB is a downstream mediator of the GSK-3 signaling cascade. It may conclude that acute stress associated decrease in p-GSK-3β-S9 and increase in p-NF-kB levels in the brain contribute in the development of behavioral and biochemical alterations and normalization of GSK-3β/NF-kB signaling may contribute in stress adaptive behavior in response to repeated electric foot shock-subjected mice. Copyright © 2016 Elsevier B.V. All rights reserved.

  5. Determination of the optimum temperature history of inlet water for minimizing thermal stresses in a pipe by the multiphysics inverse analysis

    International Nuclear Information System (INIS)

    Kubo, S; Uchida, K; Ishizaka, T; Ioka, S

    2008-01-01

    It is important to reduce the thermal stresses for managing and extending the lives of pipes in plants. In this problem, heat conduction, elastic deformation, heat transfer, liquid flow should be considered, and therefore the problem is of a multidisciplinary nature. An inverse method was proposed by the present authors for determining the optimum thermal load history which reduced transient thermal stress considering the multidisciplinary physics. But the obtained solution had a problem that the temperature increasing rate of inner surface of the pipe was discontinuous at the end time of heat up. In this study we introduce temperature history functions that ensure the continuity of the temperature increasing rate. The multidisciplinary complex problem is decomposed into a heat conduction problem, a heat transfer problem, and a thermal stress problem. An analytical solution of the temperature distribution of radial thickness and thermal hoop stress distribution is obtained. The maximum tensile and compressive hoop stresses are minimized for the case where inner surface temperature T s (t) is expressed in terms of the 4th order polynomial function of time t. Finally, from the temperature distributions, the optimum fluid temperature history is obtained for reducing the thermal stresses.

  6. AAV delivery of GRP78/BiP promotes adaptation of human RPE cell to ER stress.

    Science.gov (United States)

    Ghaderi, Shima; Ahmadian, Shahin; Soheili, Zahra-Soheila; Ahmadieh, Hamid; Samiei, Shahram; Kheitan, Samira; Pirmardan, Ehsan R

    2018-02-01

    Adeno associated virus (AAV)-mediated gene delivery of GRP78 (78 kDa glucose-regulated protein) attenuates the condition of endoplasmic reticulum (ER) stress and prevents apoptotic loss of photoreceptors in Retinitis pigmentosa (RP) rats. In the current study we overexpressed Grp78 with the help of AAV-2 in primary human retinal pigmented epithelium (hRPE) cell cultures and examined its effect on cell response to ER stress. The purpose of this work was studying potential stimulating effect of GRP78 on adaptation/pro-survival of hRPE cells under ER stress, as an in vitro model for RPE degeneration. To investigate the effect of Grp78 overexpression on unfolded protein response (UPR) markers under ER stress, hRPE primary cultures were transduced by recombinant virus rAAV/Grp78, and treated with ER stressor drug, tunicamycin. Expression changes of four UPR markers including GRP78, PERK, ATF6α, and GADD153/CHOP, were assessed by real-time PCR and western blotting. We found that GRP78 has a great contribution in modulation of UPR markers to favor adaptive response in ER-stressed hRPE cells. In fact, GRP78 overexpression affected adaptation and apoptotic phases of early UPR, through enhancement of two master regulators/ER stress sensors (PERK and ATF6α) and down-regulation of a key pro-apoptotic cascade activator (GADD153/CHOP). Together these findings demonstrate the promoting effect of GRP78 on adaptation/pro-survival of hRPE cells under ER stress. This protein with anti-apoptotic actions in the early UPR and important role in cell fate regulation, can be recruited as a useful candidate for future investigations of RPE degenerative diseases. © 2017 Wiley Periodicals, Inc.

  7. Induced thermal stress on serotonin levels in the blue swimmer crab, Portunus pelagicus

    Directory of Open Access Journals (Sweden)

    Saravanan Rajendiran

    2016-03-01

    Full Text Available The temperature of habitat water has a drastic influence on the behavioral, physiological and biochemical mechanisms of crustaceans. Hyperglycemia is a typical response of many aquatic animals to harmful physical and chemical environmental changes. In crustaceans increased circulating crustacean hyperglycemic hormone (CHH and hyperglycemia are reported to occur following exposure to several environmental stress. The biogenic amine, serotonin has been found to modulate the CHH levels and oxidation of serotonin into its metabolites is catalysed by monoamine oxidase. The blue swimmer crab, Portunus pelagicus is a dominant intertidal species utilized throughout the indo-pacific region and is a particularly important species of Palk bay. It has high nutritional value and delicious taste and hence their requirements of capture and cultivation of this species are constantly increasing. This species experiences varying and increasing temperature levels as it resides in an higher intertidal zone of Thondi coast. The present study examines the effect of thermal stress on the levels of serotonin and crustacean hyperglycemic hormone in the hemolymph of P. pelagicus and analyzes the effect of the monoamine oxidase inhibitor, pargyline on serotonin and CHH level after thermal stress. The results showed increased levels of glucose, CHH and serotonin on exposure to 26 °C in control animals. Pargyline injected crabs showed highly significant increase in the levels of CHH and serotonin on every 2 °C increase or decrease in temperature. A greater CHH level of 268.86±2.87 fmol/ml and a greater serotonin level of 177.69±10.10 ng/ml was observed at 24 °C. This could be due to the effect of in maintaining the level of serotonin in the hemolymph and preventing its oxidation, which in turn induces hyperglycemia by releasing CHH into hemolymph. Thus, the study demonstrates the effect of thermal stress on the hemolymph metabolites studied and the role of

  8. Induced thermal stress on serotonin levels in the blue swimmer crab, Portunus pelagicus.

    Science.gov (United States)

    Rajendiran, Saravanan; Muhammad Iqbal, Beema Mahin; Vasudevan, Sugumar

    2016-03-01

    The temperature of habitat water has a drastic influence on the behavioral, physiological and biochemical mechanisms of crustaceans. Hyperglycemia is a typical response of many aquatic animals to harmful physical and chemical environmental changes. In crustaceans increased circulating crustacean hyperglycemic hormone (CHH) and hyperglycemia are reported to occur following exposure to several environmental stress. The biogenic amine, serotonin has been found to modulate the CHH levels and oxidation of serotonin into its metabolites is catalysed by monoamine oxidase. The blue swimmer crab, Portunus pelagicus is a dominant intertidal species utilized throughout the indo-pacific region and is a particularly important species of Palk bay. It has high nutritional value and delicious taste and hence their requirements of capture and cultivation of this species are constantly increasing. This species experiences varying and increasing temperature levels as it resides in an higher intertidal zone of Thondi coast. The present study examines the effect of thermal stress on the levels of serotonin and crustacean hyperglycemic hormone in the hemolymph of P. pelagicus and analyzes the effect of the monoamine oxidase inhibitor, pargyline on serotonin and CHH level after thermal stress. The results showed increased levels of glucose, CHH and serotonin on exposure to 26 °C in control animals. Pargyline injected crabs showed highly significant increase in the levels of CHH and serotonin on every 2 °C increase or decrease in temperature. A greater CHH level of 268.86±2.87 fmol/ml and a greater serotonin level of 177.69±10.10 ng/ml was observed at 24 °C. This could be due to the effect of in maintaining the level of serotonin in the hemolymph and preventing its oxidation, which in turn induces hyperglycemia by releasing CHH into hemolymph. Thus, the study demonstrates the effect of thermal stress on the hemolymph metabolites studied and the role of pargyline in elevating the

  9. Magneto thermal convection in a compressible couple-stress fluid

    Energy Technology Data Exchange (ETDEWEB)

    Singh, Mahinder [Lovely School of Science, Dept. of Mathematics, Lovely Professional Univ., Phagwara (India); Kumar, Pardeep [Dept. of Mathematics, ICDEOL, H.P. Univ., Shimla (India)

    2010-03-15

    The problem of thermal instability of compressible, electrically conducting couple-stress fluids in the presence of a uniform magnetic field is considered. Following the linearized stability theory and normal mode analysis, the dispersion relation is obtained. For stationary convection, the compressibility, couple-stress, and magnetic field postpone the onset of convection. Graphs have been plotted by giving numerical values of the parameters to depict the stability characteristics. The principle of exchange of stabilities is found to be satisfied. The magnetic field introduces oscillatory modes in the system that were non-existent in its absence. The case of overstability is also studied wherein a sufficient condition for the non-existence of overstability is obtained. (orig.)

  10. Human-biometeorological conditions and thermal perception in a Mediterranean coastal park

    Science.gov (United States)

    Saaroni, Hadas; Pearlmutter, David; Hatuka, Tali

    2015-10-01

    This study looks at the interrelation of human-biometeorological conditions, physiological thermal stress and subjective thermal perception in the design and use of a new waterfront park in Tel-Aviv, Israel. Our initial assumption was that the park's design would embody a comprehensive response to the area's ever-increasing heat stress and water shortage. However, almost half of it is covered by grass lawns, irrigated with fresh water, while the remaining area is mainly covered with concrete paving, with minimal shading and sparse trees. We hypothesized that stressful thermal conditions would prevail in the park in the summer season and would be expressed in a high discomfort perception of its users. Thermo-physiological stress conditions in a typical summer month were compared with the subjective comfort perceptions of pedestrians surveyed in the park. It was found that even during mid-day hours, the level of thermal stress tends to be relatively mild, owing largely to the strong sea breeze and despite the high intensity of solar radiation. Moreover, it appears that the largely favorable perception of comfort among individuals may also result from socio-cultural aspects related to their satisfaction with the park's aesthetic attractiveness and in fact its very existence. Adaptive planning is proposed for such vulnerable regions, which are expected to experience further aggravation in thermal comfort due to global as well as localized warming trends.

  11. The GDQ Method of Thermal Vibration Laminated Shell with Actuating Magnetostrictive Layers

    Directory of Open Access Journals (Sweden)

    C.C. Hong

    2017-06-01

    Full Text Available The research of laminated magnetostrictive shell under thermal vibration was computed by using the generalized differential quadrature (GDQ method. In the thermoelastic stress-strain equations that contain the terms linear temperature rise and the magnetostrictive material with velocity feedback control. The dynamic equilibrium differential equations with displacements were normalized and discretized into the dynamic discretized equations by the GDQ method. Two edges of laminated shell with clamped boundary conditions were considered. The values of interlaminar thermal stresses and center displacement of shell with and without velocity feedback control were calculated, respectively. The purpose of this research is to compute the time responses of displacement and stresses in the laminated magnetostrictive shell subjected to thermal vibration with suitable controlled gain values. The numerical GDQ results of displacement and stresses are also obtained and investigated. With velocity feedback and suitable control gain values are found to reduce the amplitude of displacement and stresses into a smaller value. The higher values of temperature get the higher amplitude of displacement and stresses. The GDQ results of actuating magnetostrictive shells can be applied in the field of morphing aircraft (adaptive structures and smart materials to reduce and suppress the vibration when under aero-thermal flutter.

  12. Pressure adaptation is linked to thermal adaptation in salt-saturated marine habitats.

    Science.gov (United States)

    Alcaide, María; Stogios, Peter J; Lafraya, Álvaro; Tchigvintsev, Anatoli; Flick, Robert; Bargiela, Rafael; Chernikova, Tatyana N; Reva, Oleg N; Hai, Tran; Leggewie, Christian C; Katzke, Nadine; La Cono, Violetta; Matesanz, Ruth; Jebbar, Mohamed; Jaeger, Karl-Erich; Yakimov, Michail M; Yakunin, Alexander F; Golyshin, Peter N; Golyshina, Olga V; Savchenko, Alexei; Ferrer, Manuel

    2015-02-01

    The present study provides a deeper view of protein functionality as a function of temperature, salt and pressure in deep-sea habitats. A set of eight different enzymes from five distinct deep-sea (3040-4908 m depth), moderately warm (14.0-16.5°C) biotopes, characterized by a wide range of salinities (39-348 practical salinity units), were investigated for this purpose. An enzyme from a 'superficial' marine hydrothermal habitat (65°C) was isolated and characterized for comparative purposes. We report here the first experimental evidence suggesting that in salt-saturated deep-sea habitats, the adaptation to high pressure is linked to high thermal resistance (P value = 0.0036). Salinity might therefore increase the temperature window for enzyme activity, and possibly microbial growth, in deep-sea habitats. As an example, Lake Medee, the largest hypersaline deep-sea anoxic lake of the Eastern Mediterranean Sea, where the water temperature is never higher than 16°C, was shown to contain halopiezophilic-like enzymes that are most active at 70°C and with denaturing temperatures of 71.4°C. The determination of the crystal structures of five proteins revealed unknown molecular mechanisms involved in protein adaptation to poly-extremes as well as distinct active site architectures and substrate preferences relative to other structurally characterized enzymes. © 2014 Society for Applied Microbiology and John Wiley & Sons Ltd.

  13. Thermal-stress analysis of HTGR fuel and control rod fuel blocks in in-block carbonization and annealing furnace

    International Nuclear Information System (INIS)

    Gwaltney, R.C.; McAfee, W.J.

    1977-01-01

    A new method for performing thermal stress analyses in structures with multiple penetrations was applied to these analyses. This method couples the development of an equivalent thermal conductivity for the blocks, a technique that has been used extensively for modeling the thermal characteristics of reactor cores, with the use of the equivalent solid plate method for stress analysis. Using this equivalent thermal conductivity, which models as one material the heat transfer characteristics of the fuel, coolant, and graphite two-dimensional, steady-state thermal analyses of the fuel and control rod fuel blocks were performed to establish all temperature boundaries required for the stress analyses. In applying the equivalent solid plate method, the region of penetrations being modeled was replaced by a pseudo material having the same dimensions but whose materials properties were adjusted to account for the penetration. The peak stresses and strains were determined by applying stress and strain intensification factors to the calculated distributions. The condition studied was where the blocks were located near the center of the furnace. In this position, the axial surface of the block is heated near one end and cooled near the other. The approximate axial surface temperatures ranged from 1521 0 C at both the heated and the cooled ends to a peak of 1800 0 C near the center. Five specific cases were analyzed: plane (two-dimensional thermal, plane stress strain) analyses of each end of a standard fuel block (2 cases), plane analyses of each end of a control rod fuel block (2 cases), and a two-dimensional analysis of a fuel block treated as an axisymmetric cylind

  14. Simulation of thermal stresses in anode-supported solid oxide fuel cell stacks. Part II: Loss of gas-tightness, electrical contact and thermal buckling

    Science.gov (United States)

    Nakajo, Arata; Wuillemin, Zacharie; Van herle, Jan; Favrat, Daniel

    Structural stability issues in planar solid oxide fuel cells arise from the mismatch between the coefficients of thermal expansion of the components. The stress state at operating temperature is the superposition of several contributions, which differ depending on the component. First, the cells accumulate residual stresses due to the sintering phase during the manufacturing process. Further, the load applied during assembly of the stack to ensure electric contact and flatten the cells prevents a completely stress-free expansion of each component during the heat-up. Finally, thermal gradients cause additional stresses in operation. The temperature profile generated by a thermo-electrochemical model implemented in an equation-oriented process modelling tool (gPROMS) was imported into finite-element software (ABAQUS) to calculate the distribution of stress and contact pressure on all components of a standard solid oxide fuel cell repeat unit. The different layers of the cell in exception of the cathode, i.e. anode, electrolyte and compensating layer were considered in the analysis to account for the cell curvature. Both steady-state and dynamic simulations were performed, with an emphasis on the cycling of the electrical load. The study includes two different types of cell, operation under both thermal partial oxidation and internal steam-methane reforming and two different initial thicknesses of the air and fuel compressive sealing gaskets. The results generated by the models are presented in two papers: Part I focuses on cell cracking. In the present paper, Part II, the occurrences of loss of gas-tightness in the compressive gaskets and/or electrical contact in the gas diffusion layer were identified. In addition, the dependence on temperature of both coefficients of thermal expansion and Young's modulus of the metallic interconnect (MIC) were implemented in the finite-element model to compute the plastic deformation, while the possibilities of thermal buckling

  15. Is phenotypic plasticity a key mechanism for responding to thermal stress in ants?

    Science.gov (United States)

    Oms, Cristela Sánchez; Cerdá, Xim; Boulay, Raphaël

    2017-06-01

    Unlike natural selection, phenotypic plasticity allows organisms to respond quickly to changing environmental conditions. However, plasticity may not always be adaptive. In insects, body size and other morphological measurements have been shown to decrease as temperature increases. This relationship may lead to a physiological conflict in ants, where larger body size and longer legs often confer better thermal resistance. Here, we tested the effect of developmental temperature (20, 24, 28 or 32 °C) on adult thermal resistance in the thermophilic ant species Aphaenogaster senilis. We found that no larval development occurred at 20 °C. However, at higher temperatures, developmental speed increased as expected and smaller adults were produced. In thermal resistance tests, we found that ants reared at 28 and 32 °C had half-lethal temperatures that were 2 °C higher than those of ants reared at 24 °C. Thus, although ants reared at higher temperatures were smaller in size, they were nonetheless more thermoresistant. These results show that A. senilis can exploit phenotypic plasticity to quickly adjust its thermal resistance to local conditions and that this process is independent of morphological adaptations. This mechanism may be particularly relevant given current rapid climate warming.

  16. Growth stress buildup in ion beam sputtered Mo thin films and comparative study of stress relaxation upon thermal annealing or ion irradiation

    International Nuclear Information System (INIS)

    Debelle, A.; Abadias, G.; Michel, A.; Jaouen, C.; Pelosin, V.

    2007-01-01

    In an effort to address the understanding of the origin of growth stress in thin films deposited under very energetic conditions, the authors investigated the stress state and microstructure of Mo thin films grown by ion beam sputtering (IBS) as well as the stress relaxation processes taking place during subsequent thermal annealing or ion irradiation. Different sets of samples were grown by varying the IBS deposition parameters, namely, the energy E 0 and the flux j of the primary ion beam, the target-to-sputtering gas mass ratio M 1 /M 2 as well as film thickness. The strain-stress state was determined by x-ray diffraction using the sin 2 ψ method and data analyzed using an original stress model which enabled them to correlate information at macroscopic (in terms of stress) and microscopic (in terms of defect concentration) levels. Results indicate that these refractory metallic thin films are characterized by a high compressive growth stress (-2.6 to -3.8 GPa), resulting from the creation of a large concentration (up to ∼1.4%) of point or cluster defects, due to the atomic peening mechanism. The M 1 /M 2 mass ratio enables tuning efficiently the mean deposited energy of the condensing atoms; thus, it appears to be the more relevant deposition parameter that allows modifying both the microstructure and the stress level in a significant way. The growth stress comes out to be highly unstable. It can be easily relaxed either by postgrowth thermal annealing or ion irradiation in the hundred keV range at very low dose [<0.1 dpa (displacement per atom)]. It is shown that thermal annealing induces deleterious effects such as oxidation of the film surface, decrease of the film density, and in some cases adhesion loss at the film/substrate interface, while ion irradiation allows controlling the stress level without generating any macroscopic damage

  17. Thermal stress analysis of sulfur deactivated solid oxide fuel cells

    Science.gov (United States)

    Zeng, Shumao; Parbey, Joseph; Yu, Guangsen; Xu, Min; Li, Tingshuai; Andersson, Martin

    2018-03-01

    Hydrogen sulfide in fuels can deactivate catalyst for solid oxide fuel cells, which has become one of the most critical challenges to stability. The reactions between sulfur and catalyst will cause phase changes, leading to increase in cell polarization and mechanical mismatch. A three-dimensional computational fluid dynamics (CFD) approach based on the finite element method (FEM) is thus used to investigate the polarization, temperature and thermal stress in a sulfur deactivated SOFC by coupling equations for gas-phase species, heat, momentum, ion and electron transport. The results indicate that sulfur in fuels can strongly affect the cell polarization and thermal stresses, which shows a sharp decrease in the vicinity of electrolyte when 10% nickel in the functional layer is poisoned, but they remain almost unchanged even when the poisoned Ni content was increased to 90%. This investigation is helpful to deeply understand the sulfur poisoning effects and also benefit the material design and optimization of electrode structure to enhance cell performance and lifetimes in various hydrocarbon fuels containing impurities.

  18. Thermal stress in UO2 during sintering as a possible cause of cracking

    International Nuclear Information System (INIS)

    Aragones, M.A.; Tobias, E.; Tulli, I.; Naquid, C.

    1980-01-01

    Thermal stresses arising during sintering of UO 2 pellets are evaluated numerically by the solution of coupled equations for heat transfer through the sample. Results are compared with those of a semiempirical approach reported in the literature. Better insight into the heat transfer process is obtained from the solution of the coupled equations rather than from the empirical approach. The two approaches give different results for the thermal stresses arising during sintering. The use of heating and cooling rates of approximately 0.5 0 Cs -1 is found to prevent the possibility of cracking in UO 2 pellets of radii varying from 0.6 cm to 1 cm during sintering in hydrogen or argon-hydrogen atmospheres. (author)

  19. Colorimetric Detection of Caspase 3 Activity and Reactive Oxygen Derivatives: Potential Early Indicators of Thermal Stress in Corals

    Directory of Open Access Journals (Sweden)

    Mickael Ros

    2016-01-01

    Full Text Available There is an urgent need to develop and implement rapid assessments of coral health to allow effective adaptive management in response to coastal development and global change. There is now increasing evidence that activation of caspase-dependent apoptosis plays a key role during coral bleaching and subsequent mortality. In this study, a “clinical” approach was used to assess coral health by measuring the activity of caspase 3 using a commercial kit. This method was first applied while inducing thermal bleaching in two coral species, Acropora millepora and Pocillopora damicornis. The latter species was then chosen to undergo further studies combining the detection of oxidative stress-related compounds (catalase activity and glutathione concentrations as well as caspase activity during both stress and recovery phases. Zooxanthellae photosystem II (PSII efficiency and cell density were measured in parallel to assess symbiont health. Our results demonstrate that the increased caspase 3 activity in the coral host could be detected before observing any significant decrease in the photochemical efficiency of PSII in the algal symbionts and/or their expulsion from the host. This study highlights the potential of host caspase 3 and reactive oxygen species scavenging activities as early indicators of stress in individual coral colonies.

  20. Boys with Oppositional Defiant Disorder/Conduct Disorder Show Impaired Adaptation During Stress: An Executive Functioning Study.

    Science.gov (United States)

    Schoorl, Jantiene; van Rijn, Sophie; de Wied, Minet; van Goozen, Stephanie; Swaab, Hanna

    2018-04-01

    Evidence for problems in executive functioning (EF) in children with oppositional defiant disorder/conduct disorder (ODD/CD) is mixed and the impact stress may have on EF is understudied. Working memory, sustained attention, inhibition and cognitive flexibility of boys with ODD/CD (n = 65) and non-clinical controls (n = 32) were examined under typical and stressful test conditions. Boys with ODD/CD showed impaired working memory under typical testing conditions, and impairments in working memory and sustained attention under stressful conditions. In contrast to controls, performance on sustained attention, cognitive flexibility and inhibition was less influenced by stress in boys with ODD/CD. These results suggest that boys with ODD/CD show impairments in adaptation to the environment whereas typically developing boys show adaptive changes in EF.

  1. Analysis of thermal stress of the piston during non-stationary heat flow in a turbocharged Diesel engine

    Science.gov (United States)

    Gustof, P.; Hornik, A.

    2016-09-01

    In the paper, numeric calculations of thermal stresses of the piston in a turbocharged Diesel engine in the initial phase of its work were carried out based on experimental studies and the data resulting from them. The calculations were made using a geometrical model of the piston in a five-cylinder turbocharged Diesel engine with a capacity of about 2300 cm3, with a direct fuel injection to the combustion chamber and a power rating of 85 kW. In order to determine the thermal stress, application of own mathematical models of the heat flow in characteristic surfaces of the piston was required to show real processes occurring on the surface of the analysed component. The calculations were performed using a Geostar COSMOS/M program module. A three-dimensional geometric model of the piston was created in this program based on a real component, in order to enable the calculations and analysis of thermal stresses during non-stationary heat flow. Modelling of the thermal stresses of the piston for the engine speed n=4250 min-1 and engine load λ=1.69 was carried out.

  2. Soldiers Working Internationally: Impacts of Masculinity, Military Culture, and Operational Stress on Cross-Cultural Adaptation

    Science.gov (United States)

    Keats, Patrice A.

    2010-01-01

    This paper explores the ramifications of masculinized military culture and operational stress on cross-cultural adaptation. The author examines how characteristics of military culture may obstruct effective cross-cultural adaptation by promoting a hypermasculinity that tends to oppose effective management of trauma, and thereby suppresses skills…

  3. Verification of thermal-irradiation stress analytical code VIENUS of graphite block

    International Nuclear Information System (INIS)

    Iyoku, Tatsuo; Ishihara, Masahiro; Shiozawa, Shusaku; Shirai, Hiroshi; Minato, Kazuo.

    1992-02-01

    The core graphite components of the High Temperature Engineering Test Reactor (HTTR) show both the dimensional change (irradiation shrinkage) and creep behavior due to fast neutron irradiation under the temperature and the fast neutron irradiation conditions of the HTTR. Therefore, thermal/irradiation stress analytical code, VIENUS, which treats these graphite irradiation behavior, is to be employed in order to design the core components such as fuel block etc. of the HTTR. The VIENUS is a two dimensional finite element viscoelastic stress analytical code to take account of changes in mechanical properties, thermal strain, irradiation-induced dimensional change and creep in the fast neutron irradiation environment. Verification analyses were carried out in order to prove the validity of this code based on the irradiation tests of the 8th OGL-1 fuel assembly and the fuel element of the Peach Bottom reactor. This report describes the outline of the VIENUS code and its verification analyses. (author)

  4. In situ thermal residual stress evolution in ultrathin ZnO and Ag films studied by synchrotron x-ray diffraction

    Energy Technology Data Exchange (ETDEWEB)

    Renault, P.O., E-mail: Pierre.olivier.renault@univ-poitiers.fr [Institut P' , CNRS, Universite de Poitiers, UPR 3346, 86962 Futuroscope (France); Krauss, C.; Le Bourhis, E.; Geandier, G. [Institut P' , CNRS, Universite de Poitiers, UPR 3346, 86962 Futuroscope (France); Benedetto, A. [Saint-Gobain Recherche (SGR), 93303 Aubervilliers (France); Grachev, S.Y.; Barthel, E. [Lab. Surface du Verre et Interfaces (SVI), UMR-CNRS 125, 93303 Aubervilliers (France)

    2011-12-30

    Residual-stress evolution in sputtered encapsulated ZnO/Ag/ZnO stack has been studied in-situ by synchrotron x-ray diffraction when heat treated. The ZnO/Ag/ZnO stack encapsulated into Si{sub 3}N{sub 4} layers and deposited on (001) Si substrates was thermally heated from 25 Degree-Sign C to 600 Degree-Sign C and cooled down to 25 Degree-Sign C. X-ray diffraction 2D patterns captured continuously during the heat treatment allowed monitoring the diffraction peak shifts of both Ag (15 nm thick) and ZnO (10 nm and 50 nm thick) sublayers. Due to the mismatch between the coefficients of thermal expansion, the silicon substrate induced compressive thermal stresses in the films during heating. We first observed a linear increase of the compressive stress state in both Ag and ZnO films and then a more complex elastic-stress evolution starts to operate from about 100 Degree-Sign C for Ag and about 250 Degree-Sign C for ZnO. Thermal contraction upon cooling seems to dominate so that the initial compressive film stresses relax by about 300 and 700 MPa after thermal treatment for ZnO and Ag, respectively. The overall behavior is discussed in terms of structural changes induced by the heat treatment.

  5. Combined effects of thermal stress and Cd on lysosomal biomarkers and transcription of genes encoding lysosomal enzymes and HSP70 in mussels, Mytilus galloprovincialis

    Energy Technology Data Exchange (ETDEWEB)

    Izagirre, Urtzi; Errasti, Aitzpea; Bilbao, Eider; Múgica, María; Marigómez, Ionan, E-mail: ionan.marigomez@ehu.es

    2014-04-01

    Highlights: • Thermal stress and Cd caused lysosomal enlargement and membrane destabilisation. • hex, gusb and ctsl but not hsp70 were up-regulated at elevated temperature but down-regulated by Cd. • Thermal stress influenced lysosomal responses to Cd exposure. • The presence of Cd jeopardised responsiveness against thermal stress. - Abstract: In estuaries and coastal areas, intertidal organisms may be subject to thermal stress resulting from global warming, together with pollution. In the present study, the combined effects of thermal stress and exposure to Cd were investigated in the endo-lysosomal system of digestive cells in mussels, Mytilus galloprovincialis. Mussels were maintained for 24 h at 18 °C and 26 °C seawater temperature in absence and presence of 50 μg Cd/L seawater. Cadmium accumulation in digestive gland tissue, lysosomal structural changes and membrane stability were determined. Semi-quantitative PCR was applied to reveal the changes elicited by the different experimental conditions in hexosaminidase (hex), β-glucuronidase (gusb), cathepsin L (ctsl) and heat shock protein 70 (hsp70) gene transcription levels. Thermal stress provoked lysosomal enlargement whilst Cd-exposure led to fusion of lysosomes. Both thermal stress and Cd-exposure caused lysosomal membrane destabilisation. hex, gusb and ctsl genes but not hsp70 gene were transcriptionally up-regulated as a result of thermal stress. In contrast, all the studied genes were transcriptionally down-regulated in response to Cd-exposure. Cd bioaccumulation was comparable at 18 °C and 26 °C seawater temperatures but interactions between thermal stress and Cd-exposure were remarkable both in lysosomal biomarkers and in gene transcription. hex, gusb and ctsl genes, reacted to elevated temperature in absence of Cd but not in Cd-exposed mussels. Therefore, thermal stress resulting from global warming might influence the use and interpretation of lysosomal biomarkers in marine pollution

  6. Stress and glucocorticoid receptor-dependent mechanisms in long-term memory: from adaptive responses to psychopathologies.

    Science.gov (United States)

    Finsterwald, Charles; Alberini, Cristina M

    2014-07-01

    A proper response against stressors is critical for survival. In mammals, the stress response is primarily mediated by secretion of glucocorticoids via the hypothalamic-pituitary-adrenocortical (HPA) axis and release of catecholamines through adrenergic neurotransmission. Activation of these pathways results in a quick physical response to the stress and, in adaptive conditions, mediates long-term changes in the brain that lead to the formation of long-term memories of the experience. These long-term memories are an essential adaptive mechanism that allows an animal to effectively face similar demands again. Indeed, a moderate stress level has a strong positive effect on memory and cognition, as a single arousing or moderately stressful event can be remembered for up to a lifetime. Conversely, exposure to extreme, traumatic, or chronic stress can have the opposite effect and cause memory loss, cognitive impairments, and stress-related psychopathologies such as anxiety disorders, depression and post-traumatic stress disorder (PTSD). While more effort has been devoted to the understanding of the negative effects of chronic stress, much less has been done thus far on the identification of the mechanisms engaged in the brain when stress promotes long-term memory formation. Understanding these mechanisms will provide critical information for use in ameliorating memory processes in both normal and pathological conditions. Here, we will review the role of glucocorticoids and glucocorticoid receptors (GRs) in memory formation and modulation. Furthermore, we will discuss recent findings on the molecular cascade of events underlying the effect of GR activation in adaptive levels of stress that leads to strong, long-lasting memories. Our recent data indicate that the positive effects of GR activation on memory consolidation critically engage the brain-derived neurotrophic factor (BDNF) pathway. We propose and will discuss the hypothesis that stress promotes the formation of

  7. Stress and glucocorticoid receptor-dependent mechanisms in long-term memory: from adaptive responses to psychopathologies

    Science.gov (United States)

    Finsterwald, Charles; Alberini, Cristina M.

    2013-01-01

    A proper response against stressors is critical for survival. In mammals, the stress response is primarily mediated by secretion of glucocorticoids via the hypothalamic-pituitaryadrenocortical (HPA) axis and release of catecholamines through adrenergic neurotransmission. Activation of these pathways results in a quick physical response to the stress and, in adaptive conditions, mediates long-term changes in the brain that lead to the formation of long-term memories of the experience. These long-term memories are an essential adaptive mechanism that allows an animal to effectively face similar demands again. Indeed, a moderate stress level has a strong positive effect on memory and cognition, as a single arousing or moderately stressful event can be remembered for up to a lifetime. Conversely, exposure to extreme, traumatic, or chronic stress can have the opposite effect and cause memory loss, cognitive impairments, and stress-related psychopathologies such as anxiety disorders, depression and post-traumatic stress disorder (PTSD). While more effort has been devoted to the understanding of the effects of the negative effects of chronic stress, much less has been done thus far on the identification of the mechanisms engaged in the brain when stress promotes long-term memory formation. Understanding these mechanisms will provide critical information for use in ameliorating memory processes in both normal and pathological conditions. Here, we will review the role of glucocorticoids and glucocorticoid receptors (GRs) in memory formation and modulation. Furthermore, we will discuss recent findings on the molecular cascade of events underlying the effect of GR activation in adaptive levels of stress that leads to strong, long-lasting memories. Our recent data indicate that the positive effects of GR activation on memory consolidation critically engage the brain-derived neurotrophic factor (BDNF) pathway. We propose and will discuss the hypothesis that stress promotes the

  8. Chromatin remodeling regulates catalase expression during cancer cells adaptation to chronic oxidative stress.

    Science.gov (United States)

    Glorieux, Christophe; Sandoval, Juan Marcelo; Fattaccioli, Antoine; Dejeans, Nicolas; Garbe, James C; Dieu, Marc; Verrax, Julien; Renard, Patricia; Huang, Peng; Calderon, Pedro Buc

    2016-10-01

    Regulation of ROS metabolism plays a major role in cellular adaptation to oxidative stress in cancer cells, but the molecular mechanism that regulates catalase, a key antioxidant enzyme responsible for conversion of hydrogen peroxide to water and oxygen, remains to be elucidated. Therefore, we investigated the transcriptional regulatory mechanism controlling catalase expression in three human mammary cell lines: the normal mammary epithelial 250MK primary cells, the breast adenocarcinoma MCF-7 cells and an experimental model of MCF-7 cells resistant against oxidative stress resulting from chronic exposure to H 2 O 2 (Resox), in which catalase was overexpressed. Here we identify a novel promoter region responsible for the regulation of catalase expression at -1518/-1226 locus and the key molecules that interact with this promoter and affect catalase transcription. We show that the AP-1 family member JunB and retinoic acid receptor alpha (RARα) mediate catalase transcriptional activation and repression, respectively, by controlling chromatin remodeling through a histone deacetylases-dependent mechanism. This regulatory mechanism plays an important role in redox adaptation to chronic exposure to H 2 O 2 in breast cancer cells. Our study suggests that cancer adaptation to oxidative stress may be regulated by transcriptional factors through chromatin remodeling, and reveals a potential new mechanism to target cancer cells. Copyright © 2016 Elsevier Inc. All rights reserved.

  9. Relative Quantitative Proteomic Analysis of Brucella abortus Reveals Metabolic Adaptation to Multiple Environmental Stresses

    Directory of Open Access Journals (Sweden)

    Xiaodong Zai

    2017-11-01

    Full Text Available Brucella spp. are facultative intracellular pathogens that cause chronic brucellosis in humans and animals. The virulence of Brucella primarily depends on its successful survival and replication in host cells. During invasion of the host tissue, Brucella is simultaneously subjected to a variety of harsh conditions, including nutrient limitation, low pH, antimicrobial defenses, and extreme levels of reactive oxygen species (ROS via the host immune response. This suggests that Brucella may be able to regulate its metabolic adaptation in response to the distinct stresses encountered during its intracellular infection of the host. An investigation into the differential proteome expression patterns of Brucella grown under the relevant stress conditions may contribute toward a better understanding of its pathogenesis and adaptive response. Here, we utilized a mass spectrometry-based label-free relative quantitative proteomics approach to investigate and compare global proteomic changes in B. abortus in response to eight different stress treatments. The 3 h short-term in vitro single-stress and multi-stress conditions mimicked the in vivo conditions of B. abortus under intracellular infection, with survival rates ranging from 3.17 to 73.17%. The proteomic analysis identified and quantified a total of 2,272 proteins and 74% of the theoretical proteome, thereby providing wide coverage of the B. abortus proteome. By including eight distinct growth conditions and comparing these with a control condition, we identified a total of 1,221 differentially expressed proteins (DEPs that were significantly changed under the stress treatments. Pathway analysis revealed that most of the proteins were involved in oxidative phosphorylation, ABC transporters, two-component systems, biosynthesis of secondary metabolites, the citrate cycle, thiamine metabolism, and nitrogen metabolism; constituting major response mechanisms toward the reconstruction of cellular

  10. Adaptive and Pathogenic Responses to Stress by Stem Cells during Development.

    Science.gov (United States)

    Mansouri, Ladan; Xie, Yufen; Rappolee, Daniel A

    2012-12-10

    Cellular stress is the basis of a dose-dependent continuum of responses leading to adaptive health or pathogenesis. For all cells, stress leads to reduction in macromolecular synthesis by shared pathways and tissue and stress-specific homeostatic mechanisms. For stem cells during embryonic, fetal, and placental development, higher exposures of stress lead to decreased anabolism, macromolecular synthesis and cell proliferation. Coupled with diminished stem cell proliferation is a stress-induced differentiation which generates minimal necessary function by producing more differentiated product/cell. This compensatory differentiation is accompanied by a second strategy to insure organismal survival as multipotent and pluripotent stem cells differentiate into the lineages in their repertoire. During stressed differentiation, the first lineage in the repertoire is increased and later lineages are suppressed, thus prioritized differentiation occurs. Compensatory and prioritized differentiation is regulated by at least two types of stress enzymes. AMP-activated protein kinase (AMPK) which mediates loss of nuclear potency factors and stress-activated protein kinase (SAPK) that does not. SAPK mediates an increase in the first essential lineage and decreases in later lineages in placental stem cells. The clinical significance of compensatory and prioritized differentiation is that stem cell pools are depleted and imbalanced differentiation leads to gestational diseases and long term postnatal pathologies.

  11. Adaptive and Pathogenic Responses to Stress by Stem Cells during Development

    Directory of Open Access Journals (Sweden)

    Daniel A. Rappolee

    2012-12-01

    Full Text Available Cellular stress is the basis of a dose-dependent continuum of responses leading to adaptive health or pathogenesis. For all cells, stress leads to reduction in macromolecular synthesis by shared pathways and tissue and stress-specific homeostatic mechanisms. For stem cells during embryonic, fetal, and placental development, higher exposures of stress lead to decreased anabolism, macromolecular synthesis and cell proliferation. Coupled with diminished stem cell proliferation is a stress-induced differentiation which generates minimal necessary function by producing more differentiated product/cell. This compensatory differentiation is accompanied by a second strategy to insure organismal survival as multipotent and pluripotent stem cells differentiate into the lineages in their repertoire. During stressed differentiation, the first lineage in the repertoire is increased and later lineages are suppressed, thus prioritized differentiation occurs. Compensatory and prioritized differentiation is regulated by at least two types of stress enzymes. AMP-activated protein kinase (AMPK which mediates loss of nuclear potency factors and stress-activated protein kinase (SAPK that does not. SAPK mediates an increase in the first essential lineage and decreases in later lineages in placental stem cells. The clinical significance of compensatory and prioritized differentiation is that stem cell pools are depleted and imbalanced differentiation leads to gestational diseases and long term postnatal pathologies.

  12. Stress analysis of disconnected structures in contact through finite element gaps

    International Nuclear Information System (INIS)

    Stadter, J.T.; Weiss, R.O.

    1976-07-01

    A numerical procedure is presented for analyzing thermal stress problems of disconnected structures in contact across separations or gaps. The new procedure is called SAASGAPS, an adaptation of the basic SAAS III computer program. The SAAS program uses the finite element method and allows analyses of plane and axisymmetric bodies with temperature dependent material properties, subject to thermal and mechanical loads. A secant modulus approach with a bilinear stress-strain curve is used for elastic-plastic problems. The SAASGAPS version contains all of the features of the original SAAS program. A special gap element is used together with a stress invariance principle to model the contact process. The iterative procedure implemented in SAASGAPS is described. Results are discussed for five problems involving frictionless contact. Two of these problems are associated with the thermal stress analysis of the heat shield for the Multi-Hundred Watt Radioisotope Thermoelectric Generator. Input instructions for the program are described in an appendix

  13. Effect of Young's modulus evolution on residual stress measurement of thermal barrier coatings by X-ray diffraction

    International Nuclear Information System (INIS)

    Chen, Q.; Mao, W.G.; Zhou, Y.C.; Lu, C.

    2010-01-01

    Subjected to thermal cycling, the apparent Young's modulus of air plasma-sprayed (APS) 8 wt.% Y 2 O 3 -stabilized ZrO 2 (8YSZ) thermal barrier coatings (TBCs) was measured by nanoindentation. Owing to the effects of sintering and porous microstructure, the apparent Young's modulus follows a Weibull distribution and changes from 50 to 93 GPa with an increase of thermal cycling. The evolution of residual stresses in the top coating of an 8YSZ TBC system was determined by X-ray diffraction (XRD). The residual stresses derived from the XRD data are well consistent with that obtained by the Vickers indention. It is shown that the evolution of Young's modulus plays an important role in improving the measurement precision of residual stresses in TBCs by XRD.

  14. An adaptive control application in a large thermal combined power plant

    International Nuclear Information System (INIS)

    Kocaarslan, Ilhan; Cam, Ertugrul

    2007-01-01

    In this paper, an adaptive controller was applied to a 765 MW large thermal power plant to decrease operating costs, increase quality of generated electricity and satisfy environmental concerns. Since power plants may present several operating problems such as disturbances and severe effects at operating points, design of their controllers needs to be carried out adequately. For these reasons, first, a reduced mathematical model was developed under Computer Aided Analysis and Design Package for Control (CADACS), so that the results of the experimental model have briefly been discussed. Second, conventional PID and adaptive controllers were designed and implemented under the real-time environment of the CADACS software. Additionally, the design of the adaptive model-reference and conventional PID controllers used in the power plant for real-time control were theoretically presented. All processes were realized in real-time. Due to safety restrictions, a direct connection to the sensors and actuators of the plant was not allowed. Instead a coupling to the control system was realized. This offers, in addition, the usage of the supervisory functions of an industrial process computer system. Application of the controllers indicated that the proposed adaptive controller has better performances for rise and settling times of electrical power, and enthalpy outputs than the conventional PID controller does

  15. Impact of thermal stress on the growth, size-distribution and biomass ...

    African Journals Online (AJOL)

    This paper reports an in-vivo account of the impact of thermal stress on the biomass and sizedistribution of estuarine populations of Pachymelania aurita in Epe Lagoon, Nigeria. Off all physicochemical variables investigated only water temperature was statistically different among study stations. A total of 7626 individuals of ...

  16. Defense Profiles in Adaptation Process to Sport Competition and Their Relationships with Coping, Stress and Control.

    Science.gov (United States)

    Nicolas, Michel; Martinent, Guillaume; Drapeau, Martin; Chahraoui, Khadija; Vacher, Philippe; de Roten, Yves

    2017-01-01

    The purpose of this study was to identify the potentially distinct defense profiles of athletes in order to provide insight into the complex associations that can exist between defenses and other important variables tied to performance in sports (e.g., coping, perceived stress and control) and to further our understanding of the complexity of the adaptation process in sports. Two hundred and ninety-six ( N = 296) athletes participated in a naturalistic study that involved a highly stressful situation: a sports competition. Participants were assessed before and after the competition. Hierarchical cluster analysis and a series of MANOVAs with post hoc comparisons indicated two stable defense profiles (high and low defense profiles) of athletes both before and during sport competition. These profiles differed with regards to coping, stress and control. Athletes with high defense profiles reported higher levels of coping strategies, perceived stress and control than athletes with low defense profiles. This study confirmed that defenses are involved in the psychological adaptation process and that research and intervention should not be based only on coping, but rather must include defense mechanisms in order to improve our understanding of psychological adaptation in competitive sports.

  17. Defense Profiles in Adaptation Process to Sport Competition and Their Relationships with Coping, Stress and Control

    Directory of Open Access Journals (Sweden)

    Michel Nicolas

    2017-12-01

    Full Text Available The purpose of this study was to identify the potentially distinct defense profiles of athletes in order to provide insight into the complex associations that can exist between defenses and other important variables tied to performance in sports (e.g., coping, perceived stress and control and to further our understanding of the complexity of the adaptation process in sports. Two hundred and ninety-six (N = 296 athletes participated in a naturalistic study that involved a highly stressful situation: a sports competition. Participants were assessed before and after the competition. Hierarchical cluster analysis and a series of MANOVAs with post hoc comparisons indicated two stable defense profiles (high and low defense profiles of athletes both before and during sport competition. These profiles differed with regards to coping, stress and control. Athletes with high defense profiles reported higher levels of coping strategies, perceived stress and control than athletes with low defense profiles. This study confirmed that defenses are involved in the psychological adaptation process and that research and intervention should not be based only on coping, but rather must include defense mechanisms in order to improve our understanding of psychological adaptation in competitive sports.

  18. Packaging strategies for printed circuit board components. Volume I, materials & thermal stresses.

    Energy Technology Data Exchange (ETDEWEB)

    Neilsen, Michael K. (Kansas City Plant, Kansas City, MO); Austin, Kevin N.; Adolf, Douglas Brian; Spangler, Scott W.; Neidigk, Matthew Aaron; Chambers, Robert S.

    2011-09-01

    Decisions on material selections for electronics packaging can be quite complicated by the need to balance the criteria to withstand severe impacts yet survive deep thermal cycles intact. Many times, material choices are based on historical precedence perhaps ignorant of whether those initial choices were carefully investigated or whether the requirements on the new component match those of previous units. The goal of this program focuses on developing both increased intuition for generic packaging guidelines and computational methodologies for optimizing packaging in specific components. Initial efforts centered on characterization of classes of materials common to packaging strategies and computational analyses of stresses generated during thermal cycling to identify strengths and weaknesses of various material choices. Future studies will analyze the same example problems incorporating the effects of curing stresses as needed and analyzing dynamic loadings to compare trends with the quasi-static conclusions.

  19. Effect of adaptation and heat stress on reproductive performances of fat-tail Awassi rams in eastern mediterranean

    International Nuclear Information System (INIS)

    Abi Saab, S.; Darwish, W.Y.; Aad, P.; Sleiman, F.T.; Kallassy, N.; Aad, Y.

    2011-01-01

    The Awassi fat-tail sheep is desired in the Middle East and Sahara for its hardiness and resistance. In this region, the adaptability of Awassi rams to elevated heat stress is controversial. The objective of this study was to assess the effect of ambient or testicular 43 deg C heat on semen characteristics. 12 Awassi rams of 1.2 to 2 years were allowed an initial adaptation period (P0), followed by two experimental phases (P1 and P2), each including a period of heat stress (HS1 and HS2) followed by a period of recovery from heat stress (R1and R2). Heat stress conditions were considered when ambient temperature (Group 2) or testicular environment (Group 3) reached 42 to 44 deg C. Control animals (Group 1) were exposed to ambient environmental conditions. Temperature-humidity index (THI) as a relationship of ambient temperature, wet and dry humidity effect along with respiration and pulse rate, body temperature and live body weight (BW) were measured weekly as adaptation parameters. Reproductive parameters assessed included scrotum circumference and testicular volume measured twice per heat stress period, whereas semen volume density,concentration and motility were measured twice weekly. Data were analyzed using the mixed procedure of SAS under a time series analysis model, with treatment and time nested within period as main effects, and treatment by time within period as interaction terms. Treatment means were separated using Fisher protected LSD. Results showed a THI of 25.7 during therest periods (R1 and R2), 30 during HS1 and 28 during HS2. BW decreased with ambient stress, whereas respiration rate increased during heat stress periods (HS1 and HS2). Testes volume decreased with both ambient and testicular heat stress, whereas testicular circumference was not affected by these conditions. Semen concentration decreased whereas semen volume increased with ambient but not testicular heat stress. Spermatozoa abnormalities increased in R1 following heat stress (HS1

  20. Health heat stress in the Porto Metropolitan Area – a matter of temperature or inadequate adaptation?

    Directory of Open Access Journals (Sweden)

    Monteiro, Ana

    2014-09-01

    Full Text Available The aim of this contribution is to understand the negative outcomes for human health during hot weather in a Mediterranean urban environment. Examining seasonal variations of thermal comfort in Porto, by Physiologically Equivalent Temperature (PET, and comparing expected and observed daily mortality (all causes and morbidity (all causes, respiratory and circulatory diseases, suggests that in southern Europe, people’s adaptation techniques for reducing heat stress and associated health risks need to be developed much further. Research already done in Porto shows that social and economic vulnerability must be included alongside with individual characteristics, like age, gender or genetics, when defining the thresholds above which negative health impacts begin to become severe. Findings from Porto show that a climate risk map is needed for every metropolitan area, with sufficient detail to give locally appropriate temperature thresholds taking into account both the local climate and the socio-economic conditions of every sector of the urban environment.

  1. Habitat pollution and thermal regime modify molecular stress responses to elevated temperature in freshwater mussels (Anodonta anatina: Unionidae)

    International Nuclear Information System (INIS)

    Falfushynska, H.; Gnatyshyna, L.; Yurchak, I.; Ivanina, A.; Stoliar, O.; Sokolova, I.

    2014-01-01

    Elevated temperature and pollution are common stressors in freshwater ecosystems. We study cellular stress response to acute warming in Anodonta anatina (Unionidae) from sites with different thermal regimes and pollution levels: a pristine area and an agriculturally polluted site with normal temperature regimes (F and A, respectively) and a polluted site with elevated temperature (N) from the cooling pond of an electrical power plant. Animals were exposed to different temperatures for 14 days and stress response markers were measured in gills, digestive gland and hemocytes. Mussels from site N and A had elevated background levels of lactate dehydrogenase activity indicating higher reliance on anaerobic metabolism for ATP production and/or redox maintenance. Exposure to 25 °C and 30 °C induced oxidative stress (indicated by elevated levels of lipid peroxidation products) in digestive gland and gills of mussels from A and F sites, while in mussels from N sites elevated oxidative stress was only apparent at 30 °C. Temperature-induced changes in levels of antioxidants (superoxide dismutase, metallothioneins and glutathione) were tissue- and population-specific. Acute warming led to destabilization of lysosomal membranes and increased frequencies of nuclear lesions in mussels from F and A sites but not in their counterparts from N site. Elevated temperature led to an increase in the frequency of micronuclei in hemocytes in mussels from F and A sites at 25 °C and 30 °C and in mussels from N site at 30 °C. The mussels from N site also demonstrated better survival at elevated temperature (30 °C) than their counterparts from the F and A sites. Taken together, these data indicate that long-term acclimation and/or adaptation of A. anatina to elevated temperatures result in increased thermotolerance and alleviate stress response to moderate temperature rise. In contrast, extreme warming (30 °C) is harmful to mussels from all populations indicating limit to this induced

  2. Habitat pollution and thermal regime modify molecular stress responses to elevated temperature in freshwater mussels (Anodonta anatina: Unionidae)

    Energy Technology Data Exchange (ETDEWEB)

    Falfushynska, H.; Gnatyshyna, L.; Yurchak, I. [Research Laboratory of Comparative Biochemistry and Molecular Biology, Ternopil National Pedagogical University, Kryvonosa Str 2, 46027 Ternopil (Ukraine); Ivanina, A. [Department of Biological Sciences, University of North Carolina at Charlotte, 9201 University City Blvd., Charlotte, NC 28223 (United States); Stoliar, O. [Research Laboratory of Comparative Biochemistry and Molecular Biology, Ternopil National Pedagogical University, Kryvonosa Str 2, 46027 Ternopil (Ukraine); Sokolova, I., E-mail: isokolov@uncc.edu [Department of Biological Sciences, University of North Carolina at Charlotte, 9201 University City Blvd., Charlotte, NC 28223 (United States)

    2014-12-01

    Elevated temperature and pollution are common stressors in freshwater ecosystems. We study cellular stress response to acute warming in Anodonta anatina (Unionidae) from sites with different thermal regimes and pollution levels: a pristine area and an agriculturally polluted site with normal temperature regimes (F and A, respectively) and a polluted site with elevated temperature (N) from the cooling pond of an electrical power plant. Animals were exposed to different temperatures for 14 days and stress response markers were measured in gills, digestive gland and hemocytes. Mussels from site N and A had elevated background levels of lactate dehydrogenase activity indicating higher reliance on anaerobic metabolism for ATP production and/or redox maintenance. Exposure to 25 °C and 30 °C induced oxidative stress (indicated by elevated levels of lipid peroxidation products) in digestive gland and gills of mussels from A and F sites, while in mussels from N sites elevated oxidative stress was only apparent at 30 °C. Temperature-induced changes in levels of antioxidants (superoxide dismutase, metallothioneins and glutathione) were tissue- and population-specific. Acute warming led to destabilization of lysosomal membranes and increased frequencies of nuclear lesions in mussels from F and A sites but not in their counterparts from N site. Elevated temperature led to an increase in the frequency of micronuclei in hemocytes in mussels from F and A sites at 25 °C and 30 °C and in mussels from N site at 30 °C. The mussels from N site also demonstrated better survival at elevated temperature (30 °C) than their counterparts from the F and A sites. Taken together, these data indicate that long-term acclimation and/or adaptation of A. anatina to elevated temperatures result in increased thermotolerance and alleviate stress response to moderate temperature rise. In contrast, extreme warming (30 °C) is harmful to mussels from all populations indicating limit to this induced

  3. Adaptive Skills, Behavior Problems, and Parenting Stress in Mothers of Boys with Fragile X Syndrome

    Science.gov (United States)

    Sarimski, Klaus

    2010-01-01

    The relationship of temperament, atypical behaviors, and adaptive behavior of young boys with Fragile X syndrome on mothers' parenting stress was analyzed. Twenty-six boys with Fragile X syndrome (30-88 months of age) participated. The overall development of the participants was significantly delayed with a specific profile of adaptive behaviors…

  4. Adaptation to osmotic stress provides protection against ammonium nitrate in Pelophylax perezi embryos

    International Nuclear Information System (INIS)

    Ortiz-Santaliestra, Manuel E.; Fernandez-Beneitez, Maria Jose; Lizana, Miguel; Marco, Adolfo

    2010-01-01

    The negative effects of pollution on amphibians are especially high when animals are additionally stressed by other environmental factors such as water salinity. However, the stress provoked by salinity may vary among populations because of adaptation processes. We tested the combined effect of a common fertilizer, ammonium nitrate (0-90.3 mg N-NO 3 NH 4 /L), and water salinity (0-2 per mille ) on embryos of two Pelophylax perezi populations from ponds with different salinity concentrations. Embryos exposed to the fertilizer were up to 17% smaller than controls. Survival rates of embryos exposed to a single stressor were always below 10%. The exposure to both stressors concurrently increased mortality rate (>95%) of embryos from freshwater. Since the fertilizer was lethal only when individuals were stressed by the salinity, it did not cause lethal effects on embryos naturally adapted to saline environments. Our results underscore the importance of testing multiple stressors when analyzing amphibian sensitivity to environmental pollution. - Natural resistance to salinity minimizes the impact of chemical fertilizers on amphibian embryos.

  5. Recovery in dc and rf performance of off-state step-stressed AlGaN/GaN high electron mobility transistors with thermal annealing

    International Nuclear Information System (INIS)

    Kim, Byung-Jae; Hwang, Ya-Hsi; Ahn, Shihyun; Zhu, Weidi; Dong, Chen; Lu, Liu; Ren, Fan; Holzworth, M. R.; Jones, Kevin S.; Pearton, Stephen J.; Smith, David J.; Kim, Jihyun; Zhang, Ming-Lan

    2015-01-01

    The recovery effects of thermal annealing on dc and rf performance of off-state step-stressed AlGaN/GaN high electron mobility transistors were investigated. After stress, reverse gate leakage current and sub-threshold swing increased and drain current on-off ratio decreased. However, these degradations were completely recovered after thermal annealing at 450 °C for 10 mins for devices stressed either once or twice. The trap densities, which were estimated by temperature-dependent drain-current sub-threshold swing measurements, increased after off-state step-stress and were reduced after subsequent thermal annealing. In addition, the small signal rf characteristics of stressed devices were completely recovered after thermal annealing

  6. Computational analysis of heat transfer, thermal stress and dislocation density during resistively Czochralski growth of germanium single crystal

    Science.gov (United States)

    Tavakoli, Mohammad Hossein; Renani, Elahe Kabiri; Honarmandnia, Mohtaram; Ezheiyan, Mahdi

    2018-02-01

    In this paper, a set of numerical simulations of fluid flow, temperature gradient, thermal stress and dislocation density for a Czochralski setup used to grow IR optical-grade Ge single crystal have been done for different stages of the growth process. A two-dimensional steady state finite element method has been applied for all calculations. The obtained numerical results reveal that the thermal field, thermal stress and dislocation structure are mainly dependent on the crystal height, heat radiation and gas flow in the growth system.

  7. Thermal Stress Cracking of Slide-Gate Plates in Steel Continuous Casting

    Science.gov (United States)

    Lee, Hyoung-Jun; Thomas, Brian G.; Kim, Seon-Hyo

    2016-04-01

    The slide-gate plates in a cassette assembly control the steel flow through the tundish nozzle, and may experience through-thickness cracks, caused by thermal expansion and/or mechanical constraint, leading to air aspiration and safety concerns. Different mechanisms for common and rare crack formation are investigated with the aid of a three-dimensional finite-element model of thermal mechanical behavior of the slide-gate plate assembly during bolt pretensioning, preheating, tundish filling, casting, and cooling stages. The model was validated with previous plant temperature measurements of a ladle plate during preheating and casting, and then applied to a typical tundish-nozzle slide-gate assembly. The formation mechanisms of different types of cracks in the slide-gate plates are investigated using the model and evaluated with actual slide-gate plates at POSCO. Common through-thickness radial cracks, found in every plate, are caused during casting by high tensile stress on the outside surfaces of the plates, due to internal thermal expansion. In the upper plate, these cracks may also arise during preheating or tundish filling. Excessive bolt tightening, combined with thermal expansion during casting may cause rare radial cracks in the upper and lower plates. Rare radial and transverse cracks in middle plate appear to be caused during tundish filling by impingement of molten steel on the middle of the middle plate that generates tensile stress in the surrounding refractory. The mechanical properties of the refractory, the bolt tightening conditions, and the cassette/plate design are all important to service life.

  8. Relative gene transcription and pathogenicity of enterohemorrhagic Escherichia coli after long-term adaptation to acid and salt stress

    DEFF Research Database (Denmark)

    Olesen, Inger; Jespersen, Lene

    2010-01-01

    Relative gene transcription and virulence potential, as measured by a Caco-2 adhesion assay, were investigated for three enterohemorrhagic Escherichia coli (EHEC) strains after long-term adaptation for 24 h to acid (BHI pH 5.5) and salt (BHI 4.5% (w/v) NaCl) stress. Five virulence genes (eae, lpf...... compared to EDL933 (O157:H7, raw hamburger). Long-term adaptation to salt stress significantly increased the adhesion of all three EHEC strains to Caco-2 compared to the non-stressed controls. The present study shows that long-term adaptation to food related stress factors such as acid and salt is capable...... of changing the relative transcription of important virulence and stress response genes and increasing the virulence potential as measured by adhesion to the human colonic epithelial cell line, Caco-2....

  9. The design of bonded reinforcement for thermal stresses in prestressed concrete reactor vessels

    International Nuclear Information System (INIS)

    Kotulla, B.; Hansson, V.

    1977-01-01

    This paper deals with examples of thermal loadings where instationary growth of tensile zones and redistribution of stresses by cracking are of importance. Temperatures produce, in addition to prestressing and internal pressure, the most important stresses in a prestressed concrete reactor pressure vessel. Characteristic of thermal stresses is that they are influenced to a large extent by creep of concrete and that they influence stress redistributions by temperature dependent creep data. Computations show that during the first instationary heating process of the vessel stresses are reduced by creep effects to about fifty percent of the values of the stationary elastic case at the hot face. With a following cooling, creep effects are generally much less, so this case may produce tensile stresses on the internal face of the wall which lead to cracking of the concrete. Tensile stresses first occur due to the instationary growth of the temperature field in a narrow zone near the liner. If outside this zone compressive stresses exist due to prestressing then crack spreading is limited and restraint by the parts of the wall under compression causes crack distribution even without reinforcement in this zone. Growth of cracks with the instationary spreading of tensile zones according to temperature development was calculated. These calculations take into account discrete cracks, reinforcement and different assumptions for tensile strength. Reinforcement of small diameter near the surface has the best influence on crack spacing. Calculations show that for the stationary state of cooling the forces in the reinforcement may be as low as twenty to thirty percent of the tensile force not taking into account cracking of the concrete

  10. Stress adapted embroidered meshes with a graded pattern design for abdominal wall hernia repair

    Science.gov (United States)

    Hahn, J.; Bittrich, L.; Breier, A.; Spickenheuer, A.

    2017-10-01

    Abdominal wall hernias are one of the most relevant injuries of the digestive system with 25 million patients in 2013. Surgery is recommended primarily using allogenic non-absorbable wrap-knitted meshes. These meshes have in common that their stress-strain behaviour is not adapted to the anisotropic behaviour of native abdominal wall tissue. The ideal mesh should possess an adequate mechanical behaviour and a suitable porosity at the same time. An alternative fabrication method to wrap-knitting is the embroidery technology with a high flexibility in pattern design and adaption of mechanical properties. In this study, a pattern generator was created for pattern designs consisting of a base and a reinforcement pattern. The embroidered mesh structures demonstrated different structural and mechanical characteristics. Additionally, the investigation of the mechanical properties exhibited an anisotropic mechanical behaviour for the embroidered meshes. As a result, the investigated pattern generator and the embroidery technology allow the production of stress adapted mesh structures that are a promising approach for hernia reconstruction.

  11. Genetic Adaptation to Salt Stress in Experimental Evolution of Desulfovibrio vulgaris Hildenborough

    Energy Technology Data Exchange (ETDEWEB)

    Zhou, Aifen; Hillesland, Kristina; He, Zhili; Joachimiak, Marcin; Zane, Grant; Dehal, Paramvir; Arkin, Adam; Stahl, David; Wall, Judy; Hazen, Terry; Zhou, Jizhong; Baidoo, Edward; Benke, Peter; Mukhopadhyay, Aindrila

    2010-05-17

    High salinity is one of the most common environmental stressors. In order to understand how environmental organisms adapt to salty environment, an experiment evolution with sulfate reducing bacteria Desulfovibrio vugaris Hildenborough was conducted. Control lines and salt-stressed lines (6 lines each) grown in minimal medium LS4D or LS4D + 100 mM NaCl were transferred for 1200 generations. The salt tolerance was tested with LS4D supplemented with 250 mM NaCl. Statistical analysis of the growth data suggested that all lines adapted to their evolutionary environment. In addition, the control lines performed better than the ancestor with faster growth rate, higher biomass yield and shorter lag phase under salty environment they did not evolve in. However, the salt-adapted lines performed better than the control lines on measures of growth rate and yield under salty environment, suggesting that the salt?evolved lines acquired mutations specific to having extra salt in LS4D. Growth data and gene transcription data suggested that populations tended to improve till 1000 generations and active mutations tended to be fixed at the stage of 1000 generations. Point mutations and insertion/deletions were identified in isolated colonies from salt-adapted and control lines via whole genome sequencing. Glu, Gln and Ala appears to be the major osmoprotectant in evolved salt-stressed line. Ongoing studies are now characterizing the contribution of specific mutations identified in the salt-evolved D. vulgaris.

  12. A 1-D Analytical Model for the Thermally Induced Stresses in the Mould Surface During Die Casting

    DEFF Research Database (Denmark)

    Hattel, Jesper; Hansen, Preben

    1994-01-01

    This paper presents an anlytically based method for predicting the normal stresses in a die mold surface exposed to a thermal load. A example of application of the method is the high-pressure di casting process where the surface stresses in critical cases lead to cracks. Expressions for the normal...... stresses as afunction of the thermal and mechanical properties have been developed for a casting both without and with a coating. Finally, the resulting relationships are derived and evaluated, with particular emphasis on the effect of the heat transfer coefficient between the casting and the mold....

  13. Natural selection on thermal preference, critical thermal maxima and locomotor performance.

    Science.gov (United States)

    Gilbert, Anthony L; Miles, Donald B

    2017-08-16

    Climate change is resulting in a radical transformation of the thermal quality of habitats across the globe. Whereas species have altered their distributions to cope with changing environments, the evidence for adaptation in response to rising temperatures is limited. However, to determine the potential of adaptation in response to thermal variation, we need estimates of the magnitude and direction of natural selection on traits that are assumed to increase persistence in warmer environments. Most inferences regarding physiological adaptation are based on interspecific analyses, and those of selection on thermal traits are scarce. Here, we estimate natural selection on major thermal traits used to assess the vulnerability of ectothermic organisms to altered thermal niches. We detected significant directional selection favouring lizards with higher thermal preferences and faster sprint performance at their optimal temperature. Our analyses also revealed correlational selection between thermal preference and critical thermal maxima, where individuals that preferred warmer body temperatures with cooler critical thermal maxima were favoured by selection. Recent published estimates of heritability for thermal traits suggest that, in concert with the strong selective pressures we demonstrate here, evolutionary adaptation may promote long-term persistence of ectotherms in altered thermal environments. © 2017 The Author(s).

  14. A methodology for on-line calculation of temperature and thermal stress under non-linear boundary conditions

    International Nuclear Information System (INIS)

    Botto, D.; Zucca, S.; Gola, M.M.

    2003-01-01

    In the literature many works have been written dealing with the task of on-line calculation of temperature and thermal stress for machine components and structures, in order to evaluate fatigue damage accumulation and estimate residual life. One of the most widespread methodologies is the Green's function technique (GFT), by which machine parameters such as fluid temperatures, pressures and flow rates are converted into metal temperature transients and thermal stresses. However, since the GFT is based upon the linear superposition principle, it cannot be directly used in the case of varying heat transfer coefficients. In the present work, a different methodology is proposed, based upon CMS for temperature transient calculation and upon the GFT for the related thermal stress evaluation. This new approach allows variable heat transfer coefficients to be accounted for. The methodology is applied for two different case studies, taken from the literature: a thick pipe and a nozzle connected to a spherical head, both subjected to multiple convective boundary conditions

  15. On residual stresses and homeostasis: an elastic theory of functional adaptation in living matter.

    Science.gov (United States)

    Ciarletta, P; Destrade, M; Gower, A L

    2016-04-26

    Living matter can functionally adapt to external physical factors by developing internal tensions, easily revealed by cutting experiments. Nonetheless, residual stresses intrinsically have a complex spatial distribution, and destructive techniques cannot be used to identify a natural stress-free configuration. This work proposes a novel elastic theory of pre-stressed materials. Imposing physical compatibility and symmetry arguments, we define a new class of free energies explicitly depending on the internal stresses. This theory is finally applied to the study of arterial remodelling, proving its potential for the non-destructive determination of the residual tensions within biological materials.

  16. Biological stress response terminology: Integrating the concepts of adaptive response and preconditioning stress within a hormetic dose-response framework

    International Nuclear Information System (INIS)

    Calabrese, Edward J.; Bachmann, Kenneth A.; Bailer, A. John; Bolger, P. Michael; Borak, Jonathan; Cai, Lu; Cedergreen, Nina; Cherian, M. George; Chiueh, Chuang C.; Clarkson, Thomas W.; Cook, Ralph R.; Diamond, David M.; Doolittle, David J.; Dorato, Michael A.; Duke, Stephen O.; Feinendegen, Ludwig; Gardner, Donald E.; Hart, Ronald W.; Hastings, Kenneth L.; Hayes, A. Wallace; Hoffmann, George R.; Ives, John A.; Jaworowski, Zbigniew; Johnson, Thomas E.; Jonas, Wayne B.; Kaminski, Norbert E.; Keller, John G.; Klaunig, James E.; Knudsen, Thomas B.; Kozumbo, Walter J.; Lettieri, Teresa; Liu, Shu-Zheng; Maisseu, Andre; Maynard, Kenneth I.; Masoro, Edward J.; McClellan, Roger O.; Mehendale, Harihara M.; Mothersill, Carmel; Newlin, David B.; Nigg, Herbert N.; Oehme, Frederick W.; Phalen, Robert F.; Philbert, Martin A.; Rattan, Suresh I.S.; Riviere, Jim E.; Rodricks, Joseph; Sapolsky, Robert M.; Scott, Bobby R.; Seymour, Colin; Sinclair, David A.; Smith-Sonneborn, Joan; Snow, Elizabeth T.; Spear, Linda; Stevenson, Donald E.; Thomas, Yolene; Tubiana, Maurice; Williams, Gary M.; Mattson, Mark P.

    2007-01-01

    Many biological subdisciplines that regularly assess dose-response relationships have identified an evolutionarily conserved process in which a low dose of a stressful stimulus activates an adaptive response that increases the resistance of the cell or organism to a moderate to severe level of stress. Due to a lack of frequent interaction among scientists in these many areas, there has emerged a broad range of terms that describe such dose-response relationships. This situation has become problematic because the different terms describe a family of similar biological responses (e.g., adaptive response, preconditioning, hormesis), adversely affecting interdisciplinary communication, and possibly even obscuring generalizable features and central biological concepts. With support from scientists in a broad range of disciplines, this article offers a set of recommendations we believe can achieve greater conceptual harmony in dose-response terminology, as well as better understanding and communication across the broad spectrum of biological disciplines

  17. Numerical method for analysis of temperature rises and thermal stresses around high level radioactive waste repository in granite

    International Nuclear Information System (INIS)

    Shimooka, Hiroshi

    1982-01-01

    The disposal of high-level radioactive waste should result in temperature rises and thermal stresses which change the hydraulic conductivity of the rock around the repository. For safety analysis on disposal of high-level radioactive waste into hard rock, it is necessary to find the temperature rises and thermal stresses distributions around the repository. In this paper, these distribution changes are analyzed by the use of the finite difference method. In advance of numerical analysis, it is required to simplify the shapes and properties of the repository and the rock. Several kinds of numerical models are prepared, and the results of this analysis are examined. And, the waste disposal methods are discussed from the stand-points of the temperature rise and thermal stress analysis. (author)

  18. Child Functional Independence and Maternal Psychosocial Stress as Risk Factors Threatening Adaptation in Mothers of Physically or Sensorially Handicapped Children.

    Science.gov (United States)

    Wallander, Jan L; And Others

    1990-01-01

    Investigated contribution of child functional independence and maternal psychosocial stress to adaptation of 119 mothers of physically or sensorially handicapped children between the ages of 2 and 18. Child functional independence did not uniquely explain variation in mothers' adaptation. Maternal stress was uniquely associated with maternal…

  19. Service employee adaptiveness : exploring the impact of role-stress and managerial control approaches

    OpenAIRE

    Sahadev, S; Purani, K; Panda, T

    2017-01-01

    The research aims to explore the relationships between managerial control strategies, role stress and employee adaptiveness among call center employees.\\ud Based on a conceptual model, a questionnaire based survey methodology is adopted. Data was collected from call center employees in India and the data was analysed through PLS methodology.\\ud The study finds that Outcome control and activity control increase role stress while capability control does not have a significant impact. The intera...

  20. Calculation of Local Stress and Fatigue Resistance due to Thermal Stratification on Pressurized Surge Line Pipe

    Science.gov (United States)

    Bandriyana, B.; Utaja

    2010-06-01

    Thermal stratification introduces thermal shock effect which results in local stress and fatique problems that must be considered in the design of nuclear power plant components. Local stress and fatique calculation were performed on the Pressurize Surge Line piping system of the Pressurize Water Reactor of the Nuclear Power Plant. Analysis was done on the operating temperature between 177 to 343° C and the operating pressure of 16 MPa (160 Bar). The stagnant and transient condition with two kinds of stratification model has been evaluated by the two dimensional finite elements method using the ANSYS program. Evaluation of fatigue resistance is developed based on the maximum local stress using the ASME standard Code formula. Maximum stress of 427 MPa occurred at the upper side of the top half of hot fluid pipe stratification model in the transient case condition. The evaluation of the fatigue resistance is performed on 500 operating cycles in the life time of 40 years and giving the usage value of 0,64 which met to the design requirement for class 1 of nuclear component. The out surge transient were the most significant case in the localized effects due to thermal stratification.

  1. Prognostics Approach for Power MOSFET Under Thermal-Stress

    Science.gov (United States)

    Galvan, Jose Ramon Celaya; Saxena, Abhinav; Kulkarni, Chetan S.; Saha, Sankalita; Goebel, Kai

    2012-01-01

    The prognostic technique for a power MOSFET presented in this paper is based on accelerated aging of MOSFET IRF520Npbf in a TO-220 package. The methodology utilizes thermal and power cycling to accelerate the life of the devices. The major failure mechanism for the stress conditions is dieattachment degradation, typical for discrete devices with leadfree solder die attachment. It has been determined that dieattach degradation results in an increase in ON-state resistance due to its dependence on junction temperature. Increasing resistance, thus, can be used as a precursor of failure for the die-attach failure mechanism under thermal stress. A feature based on normalized ON-resistance is computed from in-situ measurements of the electro-thermal response. An Extended Kalman filter is used as a model-based prognostics techniques based on the Bayesian tracking framework. The proposed prognostics technique reports on preliminary work that serves as a case study on the prediction of remaining life of power MOSFETs and builds upon the work presented in [1]. The algorithm considered in this study had been used as prognostics algorithm in different applications and is regarded as suitable candidate for component level prognostics. This work attempts to further the validation of such algorithm by presenting it with real degradation data including measurements from real sensors, which include all the complications (noise, bias, etc.) that are regularly not captured on simulated degradation data. The algorithm is developed and tested on the accelerated aging test timescale. In real world operation, the timescale of the degradation process and therefore the RUL predictions will be considerable larger. It is hypothesized that even though the timescale will be larger, it remains constant through the degradation process and the algorithm and model would still apply under the slower degradation process. By using accelerated aging data with actual device measurements and real

  2. AIRSF: a new entertainment adaptive framework for stress free air tTravels

    NARCIS (Netherlands)

    Liu, H.; Hu, J.; Rauterberg, G.W.M.; Inakage, M.; Cheok, A.D.

    2008-01-01

    In this paper, we present a new entertainment adaptive framework AIRSF for stress free air travels. Based on the passenger’s current and target comfort states, user entertainment preference, and context of use, the system uses a Markov decision process to recommend context-aware and personalized

  3. Adaptive population divergence and directional gene flow across steep elevational gradients in a climate‐sensitive mammal

    Science.gov (United States)

    Waterhouse, Matthew D.; Erb, Liesl P.; Beever, Erik; Russello, Michael A.

    2018-01-01

    The American pika is a thermally sensitive, alpine lagomorph species. Recent climate-associated population extirpations and genetic signatures of reduced population sizes range-wide indicate the viability of this species is sensitive to climate change. To test for potential adaptive responses to climate stress, we sampled pikas along two elevational gradients (each ~470 to 1640 m) and employed three outlier detection methods, BAYESCAN, LFMM, and BAYPASS, to scan for genotype-environment associations in samples genotyped at 30,763 SNP loci. We resolved 173 loci with robust evidence of natural selection detected by either two independent analyses or replicated in both transects. A BLASTN search of these outlier loci revealed several genes associated with metabolic function and oxygen transport, indicating natural selection from thermal stress and hypoxia. We also found evidence of directional gene flow primarily downslope from large high-elevation populations and reduced gene flow at outlier loci, a pattern suggesting potential impediments to the upward elevational movement of adaptive alleles in response to contemporary climate change. Finally, we documented evidence of reduced genetic diversity associated the south-facing transect and an increase in corticosterone stress levels associated with inbreeding. This study suggests the American pika is already undergoing climate-associated natural selection at multiple genomic regions. Further analysis is needed to determine if the rate of climate adaptation in the American pika and other thermally sensitive species will be able to keep pace with rapidly changing climate conditions.

  4. Analysis and research on thermal infrared properties and adaptability of the camouflage net

    Science.gov (United States)

    Cui, Guangzhen; Hu, Jianghua; Jian, Chaochao; Yang, Juntang

    2016-10-01

    As camouflage equipment, camouflage net which covers or obstruct the enemy reconnaissance and attack, have the compatibility such as optics, infrared, radar wave band performance. To improve the adaptive between the camouflage net with background in infrared wavelengths, the heat shield and heat integration requirements on the surface of the camouflage net was analyzed. The condition that satisfied the heat shield was when the average thermal infrared transmittance was less than 25.38% on camouflage screen surface. Studies have shown that camouflage nets and the background field fused together when infrared radiation temperature difference control is within the scope of ± 4K . Experiment on temperature contrast was tested in situ background, thermal camouflage spots and camouflage net with sponge material, the infrared heat maps was recorded in the period of experiment through the thermal imager. Results showed that the thermal inertia of camouflage net was markedly lower than the background and the exposed signs were obvious. It was difficult to reach camouflage thermal infrared fusion requirements by relying on camouflage spot emissivity, but sponge which mix with polymer resin can reduce target significance in the context of mottled and realize the fusion effect.

  5. Prediction of minimum UO2 particle size based on thermal stress initiated fracture model

    International Nuclear Information System (INIS)

    Corradini, M.

    1976-08-01

    An analytic study was employed to determine the minimum UO 2 particle size that could survive fragmentation induced by thermal stresses in a UO 2 -Na Fuel Coolant Interaction (FCI). A brittle fracture mechanics approach was the basis of the study whereby stress intensity factors K/sub I/ were compared to the fracture toughness K/sub IC/ to determine if the particle could fracture. Solid and liquid UO 2 droplets were considered each with two possible interface contact conditions; perfect wetting by the sodium or a finite heat transfer coefficient. The analysis indicated that particles below the range of 50 microns in radius could survive a UO 2 -Na fuel coolant interaction under the most severe temperature conditions without thermal stress fragmentation. Environmental conditions of the fuel-coolant interaction were varied to determine the effects upon K/sub I/ and possible fragmentation. The underlying assumptions of the analysis were investigated in light of the analytic results. It was concluded that the analytic study seemed to verify the experimental observations as to the range of the minimum particle size due to thermal stress fragmentation by FCI. However the method used when the results are viewed in light of the basic assumptions indicates that the analysis is crude at best, and can be viewed as only a rough order of magnitude analysis. The basic complexities in fracture mechanics make further investigation in this area interesting but not necessarily fruitful for the immediate future

  6. Dietary lecithin potentiates thermal tolerance and cellular stress protection of milk fish (Chanos Chanos) reared under low dose endosulfan-induced stress.

    Science.gov (United States)

    Kumar, Neeraj; Minhas, P S; Ambasankar, K; Krishnani, K K; Rana, R S

    2014-12-01

    Endosulfan is an organochlorine pesticide commonly found in aquatic environments that has been found to reduce thermal tolerance of fish. Lipotropes such as the food additive, Lecithin has been shown to improve thermal tolerance in fish species. This study was conducted to evaluate the role of lipotropes (lecithin) for enhancing the thermal tolerance of Chanos chanos reared under sublethal low dose endosulfan-induced stress. Two hundred and twenty-five fish were distributed randomly into five treatments, each with three replicates. Four isocaloric and isonitrogenous diets were prepared with graded levels of lecithin: normal water and fed with control diet (En0/L0), endosulfan-treated water and fed with control diet (En/L0), endosulfan-treated water and fed with 1% (En/L1%), 1.5% (En/L 1.5%) and 2% (En/L 2%) lecithin supplemented feed. The endosulfan in treated water was maintained at the level of 1/40th of LC50 (0.52ppb). At the end of the five weeks, critical temperature maxima (CTmax), lethal temperature maxima (LTmax), critical temperature minima (CTmin) and lethal temperature minima (LTmin) were Determined. There was a significant (Plecithin on temperature tolerance (CTmax, LTmax, CTmin and LTmin) of the groups fed with 1, 1.5 and 2% lecithin-supplemented diet compared to control and endosulfan-exposed groups. Positive correlations were observed between CT max and LTmax (R(2)=0.934) as well as between CTmin and LTmin (R(2)=0.9313). At the end of the thermal tolerance study, endosulfan-induced changes in cellular stress enzymes (Catalase, SOD and GST in liver and gill and neurotansmitter enzyme, brain AChE) were significantly (plecithin. We herein report the role of lecithin in enhancing the thermal tolerance and protection against cellular stress in fish exposed to an organochlorine pesticide. Copyright © 2014 Elsevier Ltd. All rights reserved.

  7. Baking system for ports of experimental advanced super-conducting tokamak vacuum vessel and thermal stress analysis

    International Nuclear Information System (INIS)

    Cheng Yali; Bao Liman; Song Yuntao; Yao Damao

    2006-01-01

    The baking system of Experimental Advanced Super-Conducting Toakamk (EAST) vacuum vessel is necessary to obtain the baking temperature of 150 degree C. In order to define suitable alloy heaters and achieve their reasonable layouts, thermal analysis was carried out with ANSYS code. The analysis results indicate that the temperature distribution and thermal stress of most parts of EAST vacuum vessel ports are uniform, satisfied for the requirement, and are safe based on ASME criterion. Feasible idea on reducing the stress focus is also considered. (authors)

  8. Development of intergranular thermal residual stresses in beryllium during cooling from processing temperatures

    Energy Technology Data Exchange (ETDEWEB)

    Brown, D.W. [Los Alamos National Laboratory, Los Alamos, NM 87545 (United States)], E-mail: dbrown@lanl.gov; Sisneros, T.A.; Clausen, B.; Abeln, S.; Bourke, M.A.M.; Smith, B.G.; Steinzig, M.L.; Tome, C.N.; Vogel, S.C. [Los Alamos National Laboratory, Los Alamos, NM 87545 (United States)

    2009-02-15

    The intergranular thermal residual stresses in texture-free solid polycrystalline beryllium were determined by comparison of crystallographic lattice parameters in solid and powder samples measured by neutron diffraction during cooling from 800 deg. C. The internal stresses are not significantly different from zero >575 deg. C and increase nearly linearly <525 deg. C. At room temperature, the c axis of an average grain is under {approx}200 MPa of compressive internal stress, and the a axis is under 100 MPa of tensile stress. For comparison, the stresses have also been calculated using an Eshelby-type polycrystalline model. The measurements and calculations agree very well when temperature dependence of elastic constants is accounted for, and no plastic relaxation is allowed in the model.

  9. Adaptive value of phenological traits in stressful environments: predictions based on seed production and laboratory natural selection.

    Directory of Open Access Journals (Sweden)

    Benjamin Brachi

    Full Text Available Phenological traits often show variation within and among natural populations of annual plants. Nevertheless, the adaptive value of post-anthesis traits is seldom tested. In this study, we estimated the adaptive values of pre- and post-anthesis traits in two stressful environments (water stress and interspecific competition, using the selfing annual species Arabidopsis thaliana. By estimating seed production and by performing laboratory natural selection (LNS, we assessed the strength and nature (directional, disruptive and stabilizing of selection acting on phenological traits in A. thaliana under the two tested stress conditions, each with four intensities. Both the type of stress and its intensity affected the strength and nature of selection, as did genetic constraints among phenological traits. Under water stress, both experimental approaches demonstrated directional selection for a shorter life cycle, although bolting time imposes a genetic constraint on the length of the interval between bolting and anthesis. Under interspecific competition, results from the two experimental approaches showed discrepancies. Estimation of seed production predicted directional selection toward early pre-anthesis traits and long post-anthesis periods. In contrast, the LNS approach suggested neutrality for all phenological traits. This study opens questions on adaptation in complex natural environment where many selective pressures act simultaneously.

  10. X-ray diffraction study of thermal stress relaxation in ZnO films deposited by magnetron sputtering

    Energy Technology Data Exchange (ETDEWEB)

    Conchon, F. [Institut P' , Universite de Poitiers-Ensma-UPR CNRS 3346, 86962 Futuroscope (France); Renault, P.O., E-mail: pierre.olivier.renault@univ-poitiers.f [Institut P' , Universite de Poitiers-Ensma-UPR CNRS 3346, 86962 Futuroscope (France); Le Bourhis, E.; Krauss, C.; Goudeau, P. [Institut P' , Universite de Poitiers-Ensma-UPR CNRS 3346, 86962 Futuroscope (France); Barthel, E.; Grachev, S. Yu.; Sondergard, E. [Lab. Surface du Verre et Interfaces (SVI), UMR 125, 93303 Aubervilliers (France); Rondeau, V.; Gy, R. [Lab. Recherche de Saint-Gobain (SGR), 93303 Aubervilliers (France); Lazzari, R.; Jupille, J. [Institut des Nanosciences de Paris (INSP), UMR 7588, 75015 Paris (France); Brun, N. [Lab. Physique des Solides (LPS), UMR 8502, 91405 Orsay (France)

    2010-12-30

    X-ray diffraction stress analyses have been performed on two different thin films deposited onto silicon substrate: ZnO and ZnO encapsulated into Si{sub 3}N{sub 4} layers. We showed that both as-deposited ZnO films are in a high compressive stress state. In situ X-ray diffraction measurements inside a furnace revealed a relaxation of the as-grown stresses at temperatures which vary with the atmosphere in the furnace and change with Si{sub 3}N{sub 4} encapsulation. The observations show that Si{sub 3}N{sub 4} films lying on both sides of the ZnO film play an important role in the mechanisms responsible for the stress relaxation during heat treatment. The different temperatures observed for relaxation in ambient and argon atmospheres suggest that the thermally activated stress relaxation may be attributed to a variation of the stoichiometry of the ZnO films. The present observations pave the way to fine tuning of the residual stresses through thermal treatment parameters.

  11. Thermal Adaptation of the Archaeal and Bacterial Lipid Membranes

    Science.gov (United States)

    Koga, Yosuke

    2012-01-01

    The physiological characteristics that distinguish archaeal and bacterial lipids, as well as those that define thermophilic lipids, are discussed from three points of view that (1) the role of the chemical stability of lipids in the heat tolerance of thermophilic organisms: (2) the relevance of the increase in the proportion of certain lipids as the growth temperature increases: (3) the lipid bilayer membrane properties that enable membranes to function at high temperatures. It is concluded that no single, chemically stable lipid by itself was responsible for the adaptation of surviving at high temperatures. Lipid membranes that function effectively require the two properties of a high permeability barrier and a liquid crystalline state. Archaeal membranes realize these two properties throughout the whole biological temperature range by means of their isoprenoid chains. Bacterial membranes meet these requirements only at or just above the phase-transition temperature, and therefore their fatty acid composition must be elaborately regulated. A recent hypothesis sketched a scenario of the evolution of lipids in which the “lipid divide” emerged concomitantly with the differentiation of archaea and bacteria. The two modes of thermal adaptation were established concurrently with the “lipid divide.” PMID:22927779

  12. Thermal Adaptation of the Archaeal and Bacterial Lipid Membranes

    Directory of Open Access Journals (Sweden)

    Yosuke Koga

    2012-01-01

    Full Text Available The physiological characteristics that distinguish archaeal and bacterial lipids, as well as those that define thermophilic lipids, are discussed from three points of view that (1 the role of the chemical stability of lipids in the heat tolerance of thermophilic organisms: (2 the relevance of the increase in the proportion of certain lipids as the growth temperature increases: (3 the lipid bilayer membrane properties that enable membranes to function at high temperatures. It is concluded that no single, chemically stable lipid by itself was responsible for the adaptation of surviving at high temperatures. Lipid membranes that function effectively require the two properties of a high permeability barrier and a liquid crystalline state. Archaeal membranes realize these two properties throughout the whole biological temperature range by means of their isoprenoid chains. Bacterial membranes meet these requirements only at or just above the phase-transition temperature, and therefore their fatty acid composition must be elaborately regulated. A recent hypothesis sketched a scenario of the evolution of lipids in which the “lipid divide” emerged concomitantly with the differentiation of archaea and bacteria. The two modes of thermal adaptation were established concurrently with the “lipid divide.”

  13. Deposition stress effects on thermal barrier coating burner rig life

    Science.gov (United States)

    Watson, J. W.; Levine, S. R.

    1984-01-01

    A study of the effect of plasma spray processing parameters on the life of a two layer thermal barrier coating was conducted. The ceramic layer was plasma sprayed at plasma arc currents of 900 and 600 amps onto uncooled tubes, cooled tubes, and solid bars of Waspalloy in a lathe with 1 or 8 passes of the plasma gun. These processing changes affected the residual stress state of the coating. When the specimens were tested in a Mach 0.3 cyclic burner rig at 1130 deg C, a wide range of coating lives resulted. Processing factors which reduced the residual stress state in the coating, such as reduced plasma temperature and increased heat dissipation, significantly increased coating life.

  14. Effects of thermal stress on the growth of an intertidal population of Ellisolandia elongata (Rhodophyta) from N-W Mediterranean Sea.

    Science.gov (United States)

    Nannini, Matteo; De Marchi, Lucia; Lombardi, Chiara; Ragazzola, Federica

    2015-12-01

    Coralline algae are calcareous algae able to build biogenic structures, thus playing a key-role as marine biodiversity promoters and calcium carbonate producers. The aim was to estimate the growth of Ellisolandia elongata under thermal stress. E. elongata were cultured for 2, 4 and 6 months under "natural" temperature (Tc) and increased temperature (Ti = Tc + 3 °C). In order to determine a possible culturing effect, growth in the field was also measured. For the first time, Alizarin Red S dye was used in high energy shallow water environments. Thallus linear extension was higher in the cultured specimens (Tc and Ti) compared to the field specimens. The carbonate mass in the field was higher than in Ti and Tc after 2, 4 months but decreased after 6 months. Partly unknown in situ environmental factors could have affected growth and calcification rates in the field while thermal adaptation could explain growth rates in the culturing experiment. Copyright © 2015 Elsevier Ltd. All rights reserved.

  15. Theoretical Research on Thermal Shock Resistance of Ultra-High Temperature Ceramics Focusing on the Adjustment of Stress Reduction Factor

    Directory of Open Access Journals (Sweden)

    Daining Fang

    2013-02-01

    Full Text Available The thermal shock resistance of ceramics depends on not only the mechanical and thermal properties of materials, but also the external constraint and thermal condition. So, in order to study the actual situation in its service process, a temperature-dependent thermal shock resistance model for ultra-high temperature ceramics considering the effects of the thermal environment and external constraint was established based on the existing theory. The present work mainly focused on the adjustment of the stress reduction factor according to different thermal shock situations. The influences of external constraint on both critical rupture temperature difference and the second thermal shock resistance parameter in either case of rapid heating or cooling conditions had been studied based on this model. The results show the necessity of adjustment of the stress reduction factor in different thermal shock situations and the limitations of the applicable range of the second thermal shock resistance parameter. Furthermore, the model was validated by the finite element method.

  16. Stress and Thermal Analysis of the In-Vessel RMP Coils in HL-2M

    International Nuclear Information System (INIS)

    Cen Yishun; Li Qiang; Cai Lijun; Jiang Jiaming; Li Guangsheng; Liu Yi; Ding Yonghua

    2013-01-01

    A set of in-vessel resonant magnetic perturbation (RMP) coils for MHD instability suppression is proposed for the design of a HL-2M tokamak. Each coil is to be fed with a current of up to 5 kA, operated in a frequency range from DC to about 1 kHz. Stainless steel (SS) jacketed mineral insulated cables are proposed for the conductor of the coils. In-vessel coils must withstand large electromagnetic (EM) and thermal loads. The support, insulation and vacuum sealing in a very limited space are crucial issues for engineering design. Hence finite element calculations are performed to verify the design, optimize the support by minimizing stress caused by EM forces on the coil conductors and work out the temperature rise occurring on the coil in different working conditions, the corresponding thermal stress caused by the thermal expansion of materials is evaluated to be allowable. The techniques to develop the in-vessel RMP coils, such as support, insulation and cooling, are discussed

  17. Propagation of internal stresses in composite materials during heating and cooling according to thermal cycles of welding

    International Nuclear Information System (INIS)

    Gukasyan, L.E.; Belov, V.V.

    1977-01-01

    Investigations of free thermal expansion of a composite material, of fibre and matrix during welding thermal cycle make it possible to estimate mean internal strain and stress in the composite components, as well as the residual internal stress and strain present in the composite material after manufacturing. The samples investigated consisted of nickel-chromium EhI445 alloy, reinforced by tungsten-rhenium alloy fibres. As the composite material was cooled and heated in course of welding, the stress and strain changed their sign twice, the first time upon heating, the second time upon cooling. After complete cooling of the composite material residual stresses in the fibre stay at the proportionality level, while those in the matrix are lower. Experimental evidence of internal stress and strain appearing in the composite material during heating are fairly consistent with calculations in the elastic region, if account is taken of the temperature of internal residual stress relaxation upon heating

  18. Numerical simulation of temperature and thermal stress for nuclear piping by using computational fluid dynamics analysis and Green’s function

    Energy Technology Data Exchange (ETDEWEB)

    Boo, Myung-Hwan [Korea Hydro and Nuclear Power Company, Daejeon (Korea, Republic of); Oh, Chang-Kyun; Kim, Hyun-Su [KEPCO Engineering and Construction Company, Gimcheon (Korea, Republic of); Choi, Choeng-Ryul [ELSOLTEC, Inc., Yongin (Korea, Republic of)

    2017-05-15

    Owing to the fact that thermal fatigue is a well-known damage mechanism in nuclear power plants, accurate stress and fatigue evaluation are highly important. Operating experience shows that the design condition is conservative compared to the actual one. Therefore, various fatigue monitoring methods have been extensively utilized to consider the actual operating data. However, defining the local temperature in the piping is difficult because temperature-measuring instruments are limited. The purpose of this paper is to define accurate local temperature in the piping and evaluate thermal stress using Green’s function (GF) by performing a series of computational fluid dynamics analyses considering the complex fluid conditions. Also, the thermal stress is determined by adopting GF and comparing it with that of the design condition. The fluid dynamics analysis result indicates that the fluid temperature slowly varies compared to the designed one even when the flow rate changes abruptly. In addition, the resulting thermal stress can significantly decrease when reflecting the actual temperature.

  19. Thermal Stress Analysis and Structure Parameter Selection for a Bi2Te3-Based Thermoelectric Module

    Science.gov (United States)

    Gao, Jun-Ling; Du, Qun-Gui; Zhang, Xiao-Dan; Jiang, Xin-Qiang

    2011-05-01

    The output power and conversion efficiency of thermoelectric modules (TEMs) are mainly determined by their material properties, i.e., Seebeck coefficient, electrical resistivity, and thermal conductivity. In practical applications, due to the influence of the harsh environment, the mechanical properties of TEMs should also be considered. Using the finite-element analysis (FEA) model in ANSYS software, we present the thermal stress distribution of a TEM based on the anisotropic mechanical properties and thermoelectric properties of hot-pressed materials. By analyzing the possibilities of damage along the cleavage plane of Bi2Te3-based thermoelectric materials and by optimizing the structure parameters, a TEM with better mechanical performance is obtained. Thus, a direction for improving the thermal stress resistance of TEMs is presented.

  20. Analysis of electrical and thermal stress effects on PCBM:P3HT solar cells by photocurrent and impedance spectroscopy modeling

    DEFF Research Database (Denmark)

    Torto, Lorenzo; Rizzo, Antonio; Cester, Andrea

    2017-01-01

    We investigated the effects of electrical stress and thermal storage by means of photocurrent, Impedance Spectroscopy and Open Circuit Voltage Decay models. The electrical stress damages only the active layer, by reducing the generation rate, the polaron separation probability and the carrier...... lifetime. The thermal stress also degrades the anode interface. This reflects on the appearance of an inflection in the I-V photocurrent shape close to the operative region....

  1. A Technique for Mitigating Thermal Stress and Extending Life Cycle of Power Electronic Converters Used for Wind Turbines

    Directory of Open Access Journals (Sweden)

    Canras Batunlu

    2015-11-01

    Full Text Available Over the last two decades, various models have been developed to assess and improve the reliability of power electronic conversion systems (PECs with a focus on those used for wind turbines. However, only few studies have dealt with mitigating the PECs thermo-mechanical effects on their reliability taking into account variations in wind characteristics. This work critically investigates this issue and attempts to offer a mitigating technique by, first, developing realistic full scale (FS and partial scale (PS induction generator models combined with two level back-to-back PECs. Subsequently, deriving a driving algorithm, which reduces PEC’s operating temperature by controlling its switching patterns. The developed switching procedure ensures minimum temperature fluctuations by adapting the variable DC link and system’s frequency of operation. It was found for both FS and PS topologies, that the generator side converters have higher mean junction temperatures where the grid side ones have more fluctuations on their thermal profile. The FS and PS cycling temperatures were reduced by 12 °C and 5 °C, respectively. Moreover, this led to a significant improvement in stress; approximately 27 MPa stress reduction for the FS induction generator PEC.

  2. Thermal Stress and Toxicity | Science Inventory | US EPA

    Science.gov (United States)

    Elevating ambient temperature above thermoneutrality exacerbates toxicity of most air pollutants, insecticides, and other toxic chemicals. On the other hand, safety and toxicity testing of toxicants and drugs is usually performed in mice and rats maintained at subthermoneutral temperatures of —22 °C. When exposed to chemical toxicants under these relatively cool conditions, rodents typically undergo a regulated hypothermic response, characterized by preference for cooler ambient temperatures and controlled reduction in core temperature. Reducing core temperature delays the clearance of most toxicants from the body; however, a mild hypothermia also improves recovery and survival from the toxicant. Raising ambient temperature to thermoneutrality and above increases the rate of clearance of the toxicant but also exacerbates toxicity. Furthermore, heat stress combined with work or exercise is likely to worsen toxicity. Body temperature of large mammals, including humans, does not decrease as much in response to exposure to a toxicant. However, heat stress tan nonetheless worsen toxic outcome in humans through a variety of mechanisms. For example, heat-induced sweating and elevation in skin blood flow accelerates uptake of some insecticides. Epidemiological studies suggest that thermal stress may exacerbate the toxicity of airborne pollutants such as ozone and particulate matter. Overall, translating results of studies in rodents to that of humans is a formidable

  3. GADD34 Function in Protein Trafficking Promotes Adaptation to Hyperosmotic Stress in Human Corneal Cells

    Directory of Open Access Journals (Sweden)

    Dawid Krokowski

    2017-12-01

    Full Text Available Summary: GADD34, a stress-induced regulatory subunit of the phosphatase PP1, is known to function in hyperosmotic stress through its well-known role in the integrated stress response (ISR pathway. Adaptation to hyperosmotic stress is important for the health of corneal epithelial cells exposed to changes in extracellular osmolarity, with maladaptation leading to dry eye syndrome. This adaptation includes induction of SNAT2, an endoplasmic reticulum (ER-Golgi-processed protein, which helps to reverse the stress-induced loss of cell volume and promote homeostasis through amino acid uptake. Here, we show that GADD34 promotes the processing of proteins synthesized on the ER during hyperosmotic stress independent of its action in the ISR. We show that GADD34/PP1 phosphatase activity reverses hyperosmotic-stress-induced Golgi fragmentation and is important for cis- to trans-Golgi trafficking of SNAT2, thereby promoting SNAT2 plasma membrane localization and function. These results suggest that GADD34 is a protective molecule for ocular diseases such as dry eye syndrome. : Here, Krokowski et al. show that GADD34/PP1 protects the microtubule network, prevents Golgi fragmentation, and preserves protein trafficking independent of its action in the integrated stress response (ISR. In osmoadaptation, GADD34 facilitates trans-Golgi-mediated processing of the endoplasmic reticulum (ER-synthesized amino acid transporter SNAT2, which in turn increases amino acid uptake. Keywords: SNAT2, GADD34, hyperosmotic stress, amino acid transport, Golgi fragmentation, ISR

  4. Piecewise linear approximations to model the dynamics of adaptation to osmotic stress by food-borne pathogens.

    Science.gov (United States)

    Métris, Aline; George, Susie M; Ropers, Delphine

    2017-01-02

    Addition of salt to food is one of the most ancient and most common methods of food preservation. However, little is known of how bacterial cells adapt to such conditions. We propose to use piecewise linear approximations to model the regulatory adaptation of Escherichiacoli to osmotic stress. We apply the method to eight selected genes representing the functions known to be at play during osmotic adaptation. The network is centred on the general stress response factor, sigma S, and also includes a module representing the catabolic repressor CRP-cAMP. Glutamate, potassium and supercoiling are combined to represent the intracellular regulatory signal during osmotic stress induced by salt. The output is a module where growth is represented by the concentration of stable RNAs and the transcription of the osmotic gene osmY. The time course of gene expression of transport of osmoprotectant represented by the symporter proP and of the osmY is successfully reproduced by the network. The behaviour of the rpoS mutant predicted by the model is in agreement with experimental data. We discuss the application of the model to food-borne pathogens such as Salmonella; although the genes considered have orthologs, it seems that supercoiling is not regulated in the same way. The model is limited to a few selected genes, but the regulatory interactions are numerous and span different time scales. In addition, they seem to be condition specific: the links that are important during the transition from exponential to stationary phase are not all needed during osmotic stress. This model is one of the first steps towards modelling adaptation to stress in food safety and has scope to be extended to other genes and pathways, other stresses relevant to the food industry, and food-borne pathogens. The method offers a good compromise between systems of ordinary differential equations, which would be unmanageable because of the size of the system and for which insufficient data are available

  5. Psychosocial stress based on public speech in humans: is there a real life/laboratory setting cross-adaptation?

    Science.gov (United States)

    Jezova, D; Hlavacova, N; Dicko, I; Solarikova, P; Brezina, I

    2016-07-01

    Repeated or chronic exposure to stressors is associated with changes in neuroendocrine responses depending on the type, intensity, number and frequency of stress exposure as well as previous stress experience. The aim of the study was to test the hypothesis that salivary cortisol and cardiovascular responses to real-life psychosocial stressors related to public performance can cross-adapt with responses to psychosocial stress induced by public speech under laboratory setting. The sample consisted of 22 healthy male volunteers, which were either actors, more precisely students of dramatic arts or non-actors, students of other fields. The stress task consisted of 15 min anticipatory preparation phase and 15 min of public speech on an emotionally charged topic. The actors, who were accustomed to public speaking, responded with a rise in salivary cortisol as well as blood pressure to laboratory public speech. The values of salivary cortisol, systolic blood pressure and state anxiety were lower in actors compared to non-actors. Unlike non-actors, subjects with experience in public speaking did not show stress-induced rise in the heart rate. Evaluation of personality traits revealed that actors scored significantly higher in extraversion than the subjects in the non-actor group. In conclusion, neuroendocrine responses to real-life stressors in actors can partially cross-adapt with responses to psychosocial stress under laboratory setting. The most evident adaptation was at the level of heart rate responses. The public speech tasks may be of help in evaluation of the ability to cope with stress in real life in artists by simple laboratory testing.

  6. Thermal creep and stress-affected precipitation of 20% cold-worked 316 stainless steel

    International Nuclear Information System (INIS)

    Puigh, R.J.; Lovell, A.J.; Garner, F.A.

    1984-01-01

    Measurements of the thermal creep of 20% cold-worked 316 stainless steel have been performed for temperatures from 593 to 760 0 C, stress levels as high as 138 MPa and exposure times as long as 15,000 hours. The creep strains exhibit a complex behavior arising from the combined action of true creep and stress-affected precipitation of intermetallic phases. The latter process is suspected to be altered by neutron irradiation. (orig.)

  7. Thermal stress comparison in modular power converter topologies for smart transformers in the electrical distribution system

    DEFF Research Database (Denmark)

    Andresen, Markus; Ma, Ke; Liserre, Marco

    2015-01-01

    A Smart Transformer (ST) can cover an important managing role in the future electrical distribution grid. For the moment, the reliability and cost are not competitive with traditional transformers and create a barrier for its application. This work conduct detail designs and analysis...... for a promising modular ST solution, which is composed of Modular Multi-level converter, Quad Active Bridge DC-DC converters, and two-level voltage source converters. The focus is put on the loading conditions and thermal stress of power semiconductor devices in order to discover critical parts of the whole...... system when performing various mission profiles in the realistic distribution grid. It is concluded that the thermal stress for all stages is low during normal operation and especially the isolation stage is stressed least....

  8. Effect of thermal exposure on the residual stress relaxation in a hardened cylindrical sample under creep conditions

    Science.gov (United States)

    Radchenko, V. P.; Saushkin, M. N.; Tsvetkov, V. V.

    2016-05-01

    This paper describes the effect of thermal exposure (high-temperature exposure) ( T = 675°C) on the residual creep stress relaxation in a surface hardened solid cylindrical sample made of ZhS6UVI alloy. The analysis is carried out with the use of experimental data for residual stresses after micro-shot peening and exposures to temperatures equal to T = 675°C during 50, 150, and 300 h. The paper presents the technique for solving the boundary-value creep problem for the hardened cylindrical sample with the initial stress-strain state under the condition of thermal exposure. The uniaxial experimental creep curves obtained under constant stresses of 500, 530, 570, and 600 MPa are used to construct the models describing the primary and secondary stages of creep. The calculated and experimental data for the longitudinal (axial) tensor components of residual stresses are compared, and their satisfactory agreement is determined.

  9. Residual thermal stresses in a solid sphere cast from a thermosetting material

    Science.gov (United States)

    Levitsky, M.; Shaffer, B. W.

    1975-01-01

    Expressions are developed for the residual thermal stresses in a solid sphere cast from a chemically hardening thermosetting material in a rigid spherical mold. The description of the heat generation rate and temperature variation is derived from a first-order chemical reaction. Solidification is described by the continuous transformation of the material from an inviscid liquidlike state into an elastic solid, with intermediate properties determined by the degree of chemical reaction. Residual stress components are obtained as functions of the parameters of the hardening process and the properties of the hardening material. Variation of the residual stresses with a nondimensionalized reaction rate parameter and the relative compressibility of the hardened material is discussed in detail.

  10. A Theoretical Study on Quantitative Prediction and Evaluation of Thermal Residual Stresses in Metal Matrix Composite (Case 1 : Two-Dimensional In-Plane Fiber Distribution)

    International Nuclear Information System (INIS)

    Lee, Joon Hyun; Son, Bong Jin

    1997-01-01

    Although discontinuously reinforced metal matrix composite(MMC) is one of the most promising materials for applications of aerospace, automotive industries, the thermal residual stresses developed in the MMC due to the mismatch in coefficients of thermal expansion between the matrix and the fiber under a temperature change has been pointed out as one of the serious problem in practical applications. There are very limited nondestructive techniques to measure the residual stress of composite materials. However, many difficulties have been reported in their applications. Therefore it is important to establish analytical model to evaluate the thermal residual stress of MMC for practical engineering application. In this study, an elastic model is developed to predict the average thermal residual stresses in the matrix and fiber of a misoriented short fiber composite. The thermal residual stresses are induced by the mismatch in the coefficient of the thermal expansion of the matrix and fiber when the composite is subjected to a uniform temperature change. The model considers two-dimensional in-plane fiber misorientation. The analytical formulation of the model is based on Eshelby's equivalent inclusion method and is unique in that it is able to account for interactions among fibers. This model is more general than past models to investigate the effect of parameters which might influence thermal residual stress in composites. The present model is to investigate the effects of fiber volume fraction, distribution type, distribution cut-off angle, and aspect ratio on thermal residual stress for in-plane fiber misorientation. Fiber volume fraction, aspect ratio, and distribution cut-off angle are shown to have more significant effects on the magnitude of the thermal residual stresses than fiber distribution type for in-plane misorientation

  11. Metabolite profiling of symbiont and host during thermal stress and bleaching in the coral Acropora aspera

    Science.gov (United States)

    Hillyer, Katie E.; Dias, Daniel A.; Lutz, Adrian; Wilkinson, Shaun P.; Roessner, Ute; Davy, Simon K.

    2017-03-01

    Rising seawater temperatures pose a significant threat to the persistence of coral reefs. Despite the importance of these systems, major gaps remain in our understanding of how thermal stress and bleaching affect the metabolic networks that underpin holobiont function. We applied gas chromatography-mass spectrometry (GC-MS) metabolomics to detect changes in the intracellular free metabolite pools (polar and semi-polar compounds) of in hospite dinoflagellate symbionts and their coral hosts (and any associated microorganisms) during early- and late-stage thermal bleaching (a reduction of approximately 50 and 70% in symbiont density, respectively). We detected characteristic changes to the metabolite profiles of each symbiotic partner associated with individual cellular responses to thermal, oxidative and osmotic stress, which progressed with the severity of bleaching. Alterations were also indicative of changes to energy-generating and biosynthesis pathways in both partners, with a shift to the increased catabolism of lipid stores. Specifically, in symbiont intracellular metabolite pools, we observed accumulations of multiple free fatty acids, plus the chloroplast-associated antioxidant alpha-tocopherol. In the host, we detected a decline in the abundance of pools of multiple carbohydrates, amino acids and intermediates, in addition to the antioxidant ascorbate. These findings further our understanding of the metabolic changes that occur to symbiont and host (and its associated microorganisms) during thermal bleaching. These findings also provide further insight into the largely undescribed roles of free metabolite pools in cellular homeostasis, signalling and acclimation to thermal stress in the cnidarian-dinoflagellate symbiosis.

  12. Experiencing Stress as an Influence Factor on the Level of Psychosocial Adaptation in One-Time and Repeated Offenders Punished with Imprisonment

    Directory of Open Access Journals (Sweden)

    Iwona Niewiadomska

    2015-12-01

    Full Text Available The article presents the results of research showing the relationship between experiencing stress in the first phase (perception of stressful stimuli and the second phase (stress management, and the level of psychosocial adaptation of persons who have been sentenced to imprisonment once and repeatedly. The results were obtained on the basis of surveying 296 men convicted with imprisonment. For the analysis of the level of psychosocial adaptation Julian Rotter’s Rotter Incomplete Sentences Blank (RISB was used. The perception of stressful situations was measured by Iwona Niewiadomska’s Own Life Evaluation Questionnaire. The measurement of how one deals with stressful situations was performed using Norman Endler and James Parker’s Coping Inventory for Stressful Situations (CISS and also John Marsden’s MAP Questionnaire. The results obtained indicate that there are specific elements of experiencing stress, which affect the level of psychosocial adaptation of convicted offenders: 1 regardless of the number of prison sentences served, 2 only in group of people serving the prison sentence once, 3 only in group of people repeatedly residing in prison.

  13. effect of thermal stress of short duration on the red blood cell

    African Journals Online (AJOL)

    Dr Ivanc

    2013-05-01

    May 1, 2013 ... an acute increase of temperature and metabolic rate on basic blood parameters as oxygen transport system. The effect of thermal stress was studied on the Barbus balcanicus, a species inhabiting smaller water bodies often exposed to temperature fluctuatiation. During the experiment, the fish were ...

  14. Applications of Fuzzy adaptive PID control in the thermal power plant denitration liquid ammonia evaporation

    Directory of Open Access Journals (Sweden)

    Li Jing

    2016-01-01

    Full Text Available For the control of the liquid level of liquid ammonia in thermal power plant’s ammonia vaporization room, traditional PID controller parameter tuning is difficult to adapt to complex control systems, the setting of the traditional PID controller parameters is difficult to adapt to the complex control system. For the disadvantage of bad parameter setting, poor performance and so on the fuzzy adaptive PID control is proposed. Fuzzy adaptive PID control combines the advantages of traditional PID technology and fuzzy control. By using the fuzzy controller to intelligent control the object, the performance of the PID controller is further improved, and the control precision of the system is improved[1]. The simulation results show that the fuzzy adaptive PID controller not only has the advantages of high accuracy of PID controller, but also has the characteristics of fast and strong adaptability of fuzzy controller. It realizes the optimization of PID parameters which are in the optimal state, and the maximum increase production efficiency, so that are more suitable for nonlinear dynamic system.

  15. Thermal stability of nafion membranes under mechanical stress

    Energy Technology Data Exchange (ETDEWEB)

    Quintilii, M; Struis, R [Paul Scherrer Inst. (PSI), Villigen (Switzerland)

    1997-06-01

    The feasibility of adequately modified fluoro-ionomer membranes (NAFION{sup R}) is demonstrated for the selective separation of methanol synthesis products from the raw reactor gas at temperatures around 200{sup o}C. For an economically relevant application of this concept on a technical scale the Nafion membranes should be thin ({approx_equal}10 {mu}m) and thermally stable over a long period of time (1-2 years). In cooperation with industry (Methanol Casale SA, Lugano (CH)), we test the thermal stability of Nafion hollow fibers and supported Nafion thin sheet membranes at temperatures between 160 and 200{sup o}C under mechanical stress by applying a gas pressure difference over the membrane surface ({Delta}P{<=} 40 bar). Tests with the hollow fibers revealed that Nafion has visco-elastic properties. Tests with 50 {mu}m thin Nafion sheets supported by a porous metal carrier at 200{sup o}C and {Delta}P=39 bar showed no mechanical defects over a period of 92 days. (author) 5 figs., 4 refs.

  16. Thermotolerant yeasts selected by adaptive evolution express heat stress response at 30ºC

    DEFF Research Database (Denmark)

    Caspeta, Luis; Chen, Yun; Nielsen, Jens

    2016-01-01

    to grow at increased temperature, activated a constitutive heat stress response when grown at the optimal ancestral temperature, and that this is associated with a reduced growth rate. This preventive response was perfected by additional transcriptional changes activated when the cultivation temperature...... is increased. Remarkably, the sum of global transcriptional changes activated in the thermotolerant strains when transferred from the optimal to the high temperature, corresponded, in magnitude and direction, to the global changes observed in the ancestral strain exposed to the same transition....... This demonstrates robustness of the yeast transcriptional program when exposed to heat, and that the thermotolerant strains streamlined their path to rapidly and optimally reach post-stress transcriptional and metabolic levels. Thus, long-term adaptation to heat improved yeasts ability to rapidly adapt to increased...

  17. Study of thermal stress in heat affected zones during welding

    International Nuclear Information System (INIS)

    Devaux, J.C.

    1979-01-01

    The importance of applications of welding in the nuclear industry leads to the study of the main problem concerning metal welding: sensibility to cracking. The development of computation methods allows the numerical simulation of welding effects. Due to the complexity of this problem, it is divided in three steps: thermal, metallurgical and mechanical calculus. Interactions between the 3 steps are examined. Mathematical models necessary to get residual stress (i.e. stress remaining when welding is completed and structure at ambient temperature) are described. Then parameters for metallurgical structure determination are given and compared to experiments. A508 and A533 type steels of primary coolant circuit of PWR reactors are taken as examples and the numerical simulation of a test is presented [fr

  18. Calculation of thermal stress condition in long metal cylinder under heating by continuous laser radiation

    International Nuclear Information System (INIS)

    Uglov, A.A.; Uglov, S.A.; Kulik, A.N.

    1997-01-01

    The method of determination of temperature field and unduced thermal stresses in long metallic cylinder under its heating by cw-laser normally distributed heat flux is offered. The graphically presented results of calculation show the stress maximum is placed behind of center of laser heat sport along its movement line on the cylinder surface

  19. Changes in fatty acid composition in the giant clam Tridacna maxima in response to thermal stress.

    Science.gov (United States)

    Dubousquet, Vaimiti; Gros, Emmanuelle; Berteaux-Lecellier, Véronique; Viguier, Bruno; Raharivelomanana, Phila; Bertrand, Cédric; Lecellier, Gaël J

    2016-10-15

    Temperature can modify membrane fluidity and thus affects cellular functions and physiological activities. This study examines lipid remodelling in the marine symbiotic organism, Tridacna maxima, during a time series of induced thermal stress, with an emphasis on the morphology of their symbiont Symbiodinium First, we show that the French Polynesian giant clams harbour an important proportion of saturated fatty acids (SFA), which reflects their tropical location. Second, in contrast to most marine organisms, the total lipid content in giant clams remained constant under stress, though some changes in their composition were shown. Third, the stress-induced changes in fatty acid (FA) diversity were accompanied by an upregulation of genes involved in lipids and ROS pathways. Finally, our microscopic analysis revealed that for the giant clam's symbiont, Symbiodinium, thermal stress led to two sequential cell death processes. Our data suggests that the degradation of Symbiodinium cells could provide an additional source of energy to T maxima in response to heat stress. © 2016. Published by The Company of Biologists Ltd.

  20. Adaptation of the Recent Life Changes Questionnaire (RLCQ) to measure stressful life events in adults residing in an urban megapolis in Pakistan.

    Science.gov (United States)

    Artani, Azmina; Bhamani, Shireen Shehzad; Azam, Iqbal; AbdulSultan, Moiz; Khoja, Adeel; Kamal, Ayeesha K

    2017-05-05

    Contextually relevant stressful life events are integral to the quantification of stress. None such measures have been adapted for the Pakistani population. The RLCQ developed by Richard Rahe measures stress of an individual through recording the experience of life changing events. We used qualitative methodology in order to identify contextually relevant stressors in an open ended format, using serial in-depth interviews until thematic saturation of reported stressful life events was achieved. In our next phase of adaptation, our objective was to scale each item on the questionnaire, so as to weigh each of these identified events, in terms of severity of stress. This scaling exercise was performed on 200 random participants residing in the four communities of Karachi namely Kharadar, Dhorajee, Gulshan and Garden. For analysis of the scaled tool, exploratory factor analysis was used to inform structuring. Finally, to complete the process of adaption, content and face validity exercises were performed. Content validity by subject expert review and face validity was performed by translation and back translation of the adapted RLCQ. This yielded our final adapted tool. Stressful life events emerging from the qualitative phase of the study reflect daily life stressors arising from the unstable socio-political environment. Some such events were public harassment, robbery/theft, missed life opportunities due to nepotism, extortion and threats, being a victim of state sponsored brutality, lack of electricity, water, sanitation, fuel, destruction due to natural disasters and direct or media based exposure to suicide bombing in the city. Personal or societal based relevant stressors included male child preference, having an unmarried middle aged daughter, lack of empowerment and respect reported by females. The finally adapted RLCQ incorporated "Environmental Stress" as a new category. The processes of qualitative methodology, in depth interview, community based scaling and