Sample records for the next step thermonuclear reactor

  1. Important problems of future thermonuclear reactors*

    Directory of Open Access Journals (Sweden)

    Sadowski Marek J.


    Full Text Available This paper concerns important and difficult problems connected with a design and construction of thermonuclear reactors, which have to use nuclear fusion reactions of heavy isotopes of hydrogen, i.e., deuterium (D and tritium (T. There are described conditions in which such reactions can occur, and different methods of a high-temperature plasma generation, i.e., high-current electrical discharges, intense microwave pulses, and injection of energetic neutral atoms (NBI. There are also presented experimental facilities which can contain hot plasma for an appropriate period, and particularly so-called tokamaks. The second part presents the technical problems which must be solved in order to build a thermonuclear reactor, that might be used for energetic purposes. There are considered problems connected with a choice of constructional materials for a vacuum chamber, its internal parts, external windings generating a magnetic field, and necessary shields. The next part considers the handling of radioactive tritium; the using of alpha particles (4He for additional heating of plasma; recuperation of hydrogen isotopes absorbed in the tokamak internal parts, and a removal of a helium excess. There is presented a scheme of a future thermonuclear power plant and critical comments on a road map which should enable the construction of an industrial thermonuclear reactor (DEMO.

  2. Plasma-material Interactions in Current Tokamaks and their Implications for Next-step Fusion Reactors

    Energy Technology Data Exchange (ETDEWEB)

    Federici, G.; Skinner, C.H.; Brooks, J.N.; Coad, J.P.; Grisolia, C. [and others


    The major increase in discharge duration and plasma energy in a next-step DT [deuterium-tritium] fusion reactor will give rise to important plasma-material effects that will critically influence its operation, safety, and performance. Erosion will increase to a scale of several centimeters from being barely measurable at a micron scale in today's tokamaks. Tritium co-deposited with carbon will strongly affect the operation of machines with carbon plasma-facing components. Controlling plasma wall interactions is critical to achieving high performance in present-day tokamaks and this is likely to continue to be the case in the approach to practical fusion reactors. Recognition of the important consequences of these phenomena has stimulated an internationally coordinated effort in the field of plasma-surface interactions supporting the Engineering Design Activities of the International Thermonuclear Experimental Reactor (ITER) project and significant progress has been made in better under standing these issues. This paper reviews the underlying physical processes and the existing experimental database of plasma-material interactions both in tokamaks and laboratory simulation facilities for conditions of direct relevance to next-step fusion reactors. Two main topical groups of interactions are considered: (i) erosion/redeposition from plasma sputtering and disruptions, including dust and flake generation, (ii) tritium retention and removal. The use of modeling tools to interpret the experimental results and make projections for conditions expected in future devices is explained. Outstanding technical issues and specific recommendations on potential R and D [Research and Development] avenues for their resolution are presented.

  3. Antenna design for fast ion collective Thomson scattering diagnostic for the international thermonuclear experimental reactor

    DEFF Research Database (Denmark)

    Leipold, Frank; Furtula, Vedran; Salewski, Mirko


    Fast ion physics will play an important role for the international thermonuclear experimental reactor (ITER), where confined alpha particles will affect and be affected by plasma dynamics and thereby have impacts on the overall confinement. A fast ion collective Thomson scattering (CTS) diagnostic...

  4. Estimate of the parameters for a ring-shaped {open_quotes}myxine{close_quotes} for galatea thermonuclear reactors

    Energy Technology Data Exchange (ETDEWEB)

    Morozov, A.I.; Khripunov, V.I.


    The parameters of an autonomous ring-shaped myxine are estimated in connection with the conditions for an energy-producing thermonuclear reactor operating with DT and D{sup 3}He reactions. 11 refs., 3 figs. 1 tab.

  5. Robotics: the next step?

    NARCIS (Netherlands)

    Broeders, Ivo Adriaan Maria Johannes; Kuipers, E.J.


    Abstract: Robotic systems were introduced 15 years ago to support complex endoscopic procedures. The technology is increasingly used in gastro-intestinal surgery. In this article, literature on experimental- and clinical research is reviewed and ergonomic issues are discussed. Methods: literature

  6. Management of waste from the International Thermonuclear Experimental Reactor and from future fusion power plants

    Energy Technology Data Exchange (ETDEWEB)

    Broden, K. [Association EURATOM, Nykoeping (Sweden); Lindberg, M. [Association EURATOM, Nykoeping (Sweden); Nisan, S. [The NET Team, Garching (Germany); Rocco, P. [European Commission, Institute for Advanced Materials, Joint Research Centre, Ispra (Vatican City State, Holy See) (Italy); Zucchetti, M. [Energetics Department, Polytechnic of Turin, Corso Duca degli Abruzzi 24, I-10129 Torino (Italy); Taylor, N. [Association EURATOM-UKAEA, UKAEA Fusion, Culham, Abingdon, Oxfordshire, OX14 3DB (United Kingdom); Forty, C. [Association EURATOM-UKAEA, UKAEA Fusion, Culham, Abingdon, Oxfordshire, OX14 3DB (United Kingdom)


    An important inherent advantage of fusion would be the total absence of high-level radioactive spent fuel as produced in fission reactors. Fusion will, however, produce activated material containing both activation products and tritium. Part of the material may also contain chemically toxic substances. This paper describes methods that could be used to manage these materials and also methods to reduce or entirely eliminate the waste quantities. The results are based on studies for the International Thermonuclear Experimental Reactor and also for future fusion power station designs currently under investigation within the European programme on the safety and environmental assessment of fusion power, long-term. (orig.)

  7. Moral transhumanism: the next step. (United States)

    Tennison, Michael N


    Although transhumanism offers hope for the transcendence of human biological limitations, it generates many intrinsic and consequential ethical concerns. The latter include issues such as the exacerbation of social inequalities and the exponentially increasing technological capacity to cause harm. To mitigate these risks, many thinkers have initiated investigations into the possibility of moral enhancement that could limit the power disparities facilitated by biotechnological enhancement. The arguments often focus on whether moral enhancement is morally permissible, or even obligatory, and remain largely in the realm of the hypothetical. This paper proposes that psilocybin may represent a viable, practical option for moral enhancement and that its further research in the context of moral psychology could comprise the next step in the development of moral transhumanism.

  8. Review of the International Thermonuclear Experimental Reactor (ITER) detailed design report

    Energy Technology Data Exchange (ETDEWEB)



    Dr. Martha Krebs, Director, Office of Energy Research at the US Department of Energy (DOE), wrote to the Fusion Energy Sciences Advisory Committee (FESAC), in letters dated September 23 and November 6, 1996, requesting that FESAC review the International Thermonuclear Experimental Reactor (ITER) Detailed Design Report (DDR) and provide its view of the adequacy of the DDR as part of the basis for the United States decision to enter negotiations with the other interested Parties regarding the terms and conditions for an agreement for the construction, operations, exploitation and decommissioning of ITER. The letter from Dr. Krebs, referred to as the Charge Letter, provided context for the review and a set of questions of specific interest.

  9. Economic impacts on the United States of siting decisions for the international thermonuclear experimental reactor

    Energy Technology Data Exchange (ETDEWEB)

    Peerenboom, J.P.; Hanson, M.E.; Huddleston, J.R. [and others


    This report presents the results of a study that examines and compares the probable short-term economic impacts of the International Thermonuclear Experimental Reactor (ITER) on the United States (U.S.) if (1) ITER were to be sited in the U.S., or (2) ITER were to be sited in one of the other countries that, along with the U.S., is currently participating in the ITER program. Life-cycle costs associated with ITER construction, operation, and decommissioning are analyzed to assess their economic impact. A number of possible U.S. host and U.S. non-host technology and cost-sharing arrangements with the other ITER Parties are examined, although cost-sharing arrangements and the process by which the Parties will select a host country and an ITER site remain open issues. Both national and local/regional economic impacts, as measured by gross domestic product, regional output, employment, net exports, and income, are considered. These impacts represent a portion of the complex, interrelated set of economic considerations that characterize U.S. host and U.S. non-host participation in ITER. A number of other potentially important economic and noneconomic considerations are discussed qualitatively.

  10. Economic Impacts on the United States of Siting Decisions for the International Thermonuclear Experimental Reactor (United States)

    Peerenboom, J. P.; Hanson, M. E.; Huddleston, J. R.; Wolsko, T. D.


    This paper presents the results of a study that examines and compares the probable short-term economic impacts of the International Thermonuclear Experimental Reactor (ITER) on the United States (U.S.) if (1) ITER were to be sited in the U.S., or (2) ITER were to be sited in one of the other countries that, along with the U.S., is currently participating in the ITER program. Life-cycle costs associated with ITER construction, operation, and decommissioning are analyzed to assess their economic impact. A number of possible U.S. host and U.S. non-host technology and cost-sharing arrangements with the other ITER Parties are examined, although cost-sharing arrangements and the process by which the Parties will select a host country and an ITER site remain open issues. Both national and local/regional economic impacts, as measured by gross domestic product, regional output, employment, net exports, and income, are considered. These impacts represent a portion of the complex, interrelated set of economic considerations that characterize U.S. host and U.S. non-host participation in ITER. A number of other potentially important economic and noneconomic considerations are discussed qualitatively.

  11. Vacuum pumping for controlled thermonuclear reactors

    Energy Technology Data Exchange (ETDEWEB)

    Watson, J.S.; Fisher, P.W.


    Thermonuclear reactors impose unique vacuum pumping problems involving very high pumping speeds, handling of hazardous materials (tritium), extreme cleanliness requirements, and quantitative recovery of pumped materials. Two principal pumping systems are required for a fusion reactor, a main vacuum system for evacuating the torus and a vacuum system for removing unaccelerated deuterium from neutral beam injectors. The first system must pump hydrogen isotopes and helium while the neutral beam system can operate by pumping only hydrogen isotopes (perhaps only deuterium). The most promising pumping techniques for both systems appear to be cryopumps, but different cryopumping techniques can be considered for each system. The main vacuum system will have to include cryosorption pumps cooled to 4.2/sup 0/K to pump helium, but the unburned deuterium-tritium and other impurities could be pumped with cryocondensation panels (4.2/sup 0/K) or cryosorption panels at higher temperatures. Since pumping speeds will be limited by conductance through the ducts and thermal shields, the pumping performance for both systems will be similar, and other factors such as refrigeration costs are likely to determine the choice. The vacuum pumping system for neutral beam injectors probably will not need to pump helium, and either condensation or higher temperature sorption pumps can be used.

  12. Social mobility: the next steps


    Gregg, P; Cleal, Paul; Shephard, Gillian; Milburn, Alan; Johnston, David; Attwood, Tom; Carrie, Anne Marie; Guy, Christian; Williams, Catriona; Hamilton, Douglas


    The Social Mobility and Child Poverty Commission was formally tasked by Ministers to give its view on what further steps the UK government could reasonably take to improve social mobility.The Commission advised opportunities for low paid workers to move up the career ladder, for young people to move from school to employment, and for disadvantaged youngsters to get support in their earliest years should be Ministers’ top priorities if they are to make headway on tackling the UK’s stagnating l...

  13. Transmission thermography for inspecting the busbar insulation layer in thermonuclear experimental reactor (United States)

    Chen, Dapeng; Zhang, Guang; Zhang, Xiaolong; Zeng, Zhi


    In Thermonuclear Experimental Reactor, Superconducting Busbar is used for current transmission between magnet coils and current leads. The work temperature of the Busbar is about 4K because of liquid helium via inside. The large temperature grad from 300K to 4K could lead to the defects and damages occur on the insulation layer, which is made of glass fiber and polyimide and has a big different thermal expansion coefficient compared with the metal inner cylinder. This paper aims at developing an infrared transmission non-destructive evaluation (NDE) method for inspecting the insulation layer of Superconducting Busbar; theoretical model of transient heat conduction under a continuous inner heat source for cylindrical structure is described in the paper; a Busbar specimen which is designed with three delamination defects of different depths is heated inside by pouring hot water and monitored by an infrared detector located outside. Results demonstrate excellent detection performance for delamination defects in the insulation layer by using transmission thermography, all of the three defects of different depths can be visualized clearly in the thermal images, and the deeper defect has a better signal contrast, which is also shown in the temperature difference between defects and sound area vs. time curves. The results of light pulse thermography is also shown as a comparison, and it is found that the thermal images obtained by the transmission thermography has a much better signal contrast than that of the pulse thermography. In order to verify the experiments, finite element method is applied to simulate the heat conduction in the Busbar under the continuous inside heating, and it is found that the simulated temperature vs. time and simulated temperature difference vs. time curves are basically coincident with the experimental results. In addition, the possibility of in-service inspection for Busbar insulation layer in ITER item is discussed.

  14. Software architecture : The next step

    NARCIS (Netherlands)

    Bosch, J; Oquendo, F; Warboys, B; Morrison, R


    This position paper makes the following claims that, in our opinion, are worthwhile to discuss at the workshop. 1) The first phase of software architecture research, where the key concepts are components and connectors, has matured the technology to a level where industry adoption is wide-spread and

  15. Interactive Video, The Next Step (United States)

    Strong, L. R.; Wold-Brennon, R.; Cooper, S. K.; Brinkhuis, D.


    Video has the ingredients to reach us emotionally - with amazing images, enthusiastic interviews, music, and video game-like animations-- and it's emotion that motivates us to learn more about our new interest. However, watching video is usually passive. New web-based technology is expanding and enhancing the video experience, creating opportunities to use video with more direct interaction. This talk will look at an Educaton and Outreach team's experience producing video-centric curriculum using innovative interactive media tools from TED-Ed and FlixMaster. The Consortium for Ocean Leadership's Deep Earth Academy has partnered with the Center for Dark Energy Biosphere Investigations (C-DEBI) to send educators and a video producer aboard three deep sea research expeditions to the Juan de Fuca plate to install and service sub-seafloor observatories. This collaboration between teachers, students, scientists and media producers has proved a productive confluence, providing new ways of understanding both ground-breaking science and the process of science itself - by experimenting with new ways to use multimedia during ocean-going expeditions and developing curriculum and other projects post-cruise.

  16. Modeling of secondary emission processes in the negative ion based electrostatic accelerator of the International Thermonuclear Experimental Reactor

    Directory of Open Access Journals (Sweden)

    G. Fubiani


    Full Text Available The negative ion electrostatic accelerator for the neutral beam injector of the International Thermonuclear Experimental Reactor (ITER is designed to deliver a negative deuterium current of 40 A at 1 MeV. Inside the accelerator there are several types of interactions that may create secondary particles. The dominating process originates from the single and double stripping of the accelerated negative ion by collision with the residual molecular deuterium gas (≃29% losses. The resulting secondary particles (positive ions, neutrals, and electrons are accelerated and deflected by the electric and magnetic fields inside the accelerator and may induce more secondaries after a likely impact with the accelerator grids. This chain of reactions is responsible for a non-negligible heat load on the grids and must be understood in detail. In this paper, we will provide a comprehensive summary of the physics involved in the process of secondary emission in a typical ITER-like negative ion electrostatic accelerator together with a precise description of the numerical method and approximations involved. As an example, the multiaperture-multigrid accelerator concept will be discussed.

  17. Dr Robert Aymar, Director of the International Thermonuclear Experimental Reactor (ITER), was nominated to succeed Professor Luciano Maiani as CERN's Director General, to take office on 1 January 2004.

    CERN Document Server


    Dr Robert Aymar, Director of the International Thermonuclear Experimental Reactor (ITER), was nominated to succeed Professor Luciano Maiani as CERN's Director General, to take office on 1 January 2004.

  18. Recent progress on the hydrogen storage properties of ZrCo-based alloys applied in International Thermonuclear Experimental Reactor (ITER

    Directory of Open Access Journals (Sweden)

    Feng Wang


    Full Text Available Under the development of International Thermonuclear Experimental Reactor (ITER system aimed at realizing the controllable fusion reaction to solve the energy crisis fundamentally, there is an urgent need to find an appropriate material for tritium handling. ZrCo alloy is considered to be a promising candidate for the storage and delivery of hydrogen isotopes due to the favorable characteristics such as low plateau pressure for absorption, high dissociation pressure at moderate temperature and better ability of trapping 3He. However, the hydrogen induced disproportionation and the slower recovery/deliverty rate of ZrCo-based alloys have limited their further application in ITER system. This review summarizes the efforts towards enhancing the hydrogen storage properties of ZrCo-based alloys including element substitution, surface modification, disproportionation mechanism investigation and the isotope effect study. Element substitution and surface modification play positive role to improve the anti-disproportionation ability and kinetic property of the alloys. However, the ZrCo-based alloys require to be further modified by more attempts such as new composition, novelty modification method or catalyst addition in order to better satisfy the application demands for tritium handling. Moreover, new insight for further understanding the inner disproportionation mechanisms of this material is needed by combining the advance characterization and theoretical analysis, which is in favor of addressing the disproportionation problem of the ZrCo-based alloys essentially.

  19. Next Step for STEP

    Energy Technology Data Exchange (ETDEWEB)

    Wood, Claire [CTSI; Bremner, Brenda [CTSI


    The Siletz Tribal Energy Program (STEP), housed in the Tribe’s Planning Department, will hire a data entry coordinator to collect, enter, analyze and store all the current and future energy efficiency and renewable energy data pertaining to administrative structures the tribe owns and operates and for homes in which tribal members live. The proposed data entry coordinator will conduct an energy options analysis in collaboration with the rest of the Siletz Tribal Energy Program and Planning Department staff. An energy options analysis will result in a thorough understanding of tribal energy resources and consumption, if energy efficiency and conservation measures being implemented are having the desired effect, analysis of tribal energy loads (current and future energy consumption), and evaluation of local and commercial energy supply options. A literature search will also be conducted. In order to educate additional tribal members about renewable energy, we will send four tribal members to be trained to install and maintain solar panels, solar hot water heaters, wind turbines and/or micro-hydro.

  20. Physics modeling support for the International Thermonuclear Experimental Reactor: Final report

    Energy Technology Data Exchange (ETDEWEB)


    There are two major sections to this report. The first section of the report is an executive summary of the work done this year. For each task, the major results are condensed for the reader's convenience. The major result of each memo, report or presentation is summarized briefly in this section. The second section of the report is a collection of appendices containing reports, memos, and presentations written this year. Here, the interested reader can investigate any topic discussed in the summary in more detail. The documentation is presented in chronological order, and we would like to note that the content of later documents may supercede that of earlier ones. The summaries are divided into sections, corresponding to the tasks outlined in the original proposal for the work. These sections are: MUMAK code development and application; Alfven wave stability problem; TETRA systems code development and application; lower hybrid heating and current drive; and advanced blanket modeling.

  1. ITER vacuum vessel fabrication plan and cost study (D 68) for the international thermonuclear experimental reactor

    Energy Technology Data Exchange (ETDEWEB)



    ITER Task No. 8, Vacuum Vessel Fabrication Plan and Cost Study (D68), was initiated to assess ITER vacuum vessel fabrication, assembly, and cost. The industrial team of Raytheon Engineers & Constructors and Chicago Bridge & Iron (Raytheon/CB&I) reviewed the current vessel basis and prepared a manufacturing plan, assembly plan, and cost estimate commensurate with the present design. The guidance for the Raytheon/CB&I assessment activities was prepared by the ITER Garching Work Site. This guidance provided in the form of work descriptions, sketches, drawings, and costing guidelines for each of the presently identified vacuum vessel Work Breakdown Structure (WBS) elements was compiled in ITER Garching Joint Work Site Memo (Draft No. 9 - G 15 MD 01 94-17-05 W 1). A copy of this document is provided as Appendix 1 to this report. Additional information and clarifications required for the Raytheon/CB&I assessments were coordinated through the US Home Team (USHT) and its technical representative. Design details considered essential to the Task 8 assessments but not available from the ITER Joint Central Team (JCT) were generated by Raytheon/CB&I and documented accordingly.

  2. [The next step for population policies]. (United States)

    Cabrera Acevedo, G


    In modern and postmodern societies, age has been transformed into a symbol of isolation, sadness, poverty, physical and mental inactivity, and economic and emotional burden for families, societies, and nations. Humanity has struggled to postpone death through medical advances and greater life expectancy. Declines in mortality and fertility lead inexorably to demographic aging. In Mexico, as in many other societies, poverty is concentrated at the beginning and end of life. While it has undeniably been an achievement to add years to life, social and cultural changes in response to demographic aging and greater life expectancy have not occurred. The additional years have not been accompanied by social actions that provide the elderly with a dignified and tranquil life free from want. In 1965, Mexico's population over 65 years of age was 1.7 million, accounting for 4.6% of the population, life expectancy was 57.9 years, and the total fertility rate was 6.9. In 1995, 4.4% of the population was over 65 years of age and the total fertility rate was 2.8. By 2030, a projected 17 million, or 13.1%, will be over 65 years old. The future demographic profile is the result of societal desires for better health, longer life, and fewer children living in better circumstances. The great challenge of the next century will be to create strategies, policies, and programs to attend to population aging. Collective awareness must be created of the material and other needs of the elderly, and the sociopolitical system must adapt in response.

  3. Media Literacy, Congratulations! Now, the Next Step (United States)

    Torrent, Jordi


    Media Literacy Education has definitely come a long way. The author remembers mentioning Media Literacy at a Prix Jeunesse presentation in New York City in the early-mid 1990s-- all the participants looked at him as a weirdo and politely ignored his comment on the necessity for TV producers to include or at least reflect upon media…

  4. Next step, the Tour de France?

    CERN Multimedia

    Anaïs Schaeffer


    The penultimate stage of the 2013 Tour de France, the Annecy-Semnoz time-trial, has already been won – by a CERN staff member!     In keeping with tradition, the organisers of the Tour de France organise another race, the Étape du Tour, which is open to the general public and follows the actual route of an official stage of the Tour proper. This year, the chosen venue was Annecy and its neighbouring mountain, Le Semnoz, which played host to 11,000 cycling enthusiasts from all parts. This penultimate stage of the 2013 Tour will be raced by the professionals on 20 July. The public race was won by Nicolas Roux, an experienced cyclist and member of CERN’s GS-IS Group, who devoured the 128-km course in just 4 hours and 15 minutes, nine seconds ahead of cycling champion Julien Absalon. “I just managed to overhaul Julien Absalon 500 m before the finishing line,” Nicolas recounts. “It was a fantastic race!” Come rain o...

  5. Integrated Modelling - the next steps (Invited) (United States)

    Moore, R. V.


    Integrated modelling (IM) has made considerable advances over the past decade but it has not yet been taken up as an operational tool in the way that its proponents had hoped. The reasons why will be discussed in Session U17. This talk will propose topics for a research and development programme and suggest an institutional structure which, together, could overcome the present obstacles. Their combined aim would be first to make IM into an operational tool useable by competent public authorities and commercial companies and, in time, to see it evolve into the modelling equivalent of Google Maps, something accessible and useable by anyone with a PC or an iphone and an internet connection. In a recent study, a number of government agencies, water authorities and utilities applied integrated modelling to operational problems. While the project demonstrated that IM could be used in an operational setting and had benefit, it also highlighted the advances that would be required for its widespread uptake. These were: greatly improving the ease with which models could be a) made linkable, b) linked and c) run; developing a methodology for applying integrated modelling; developing practical options for calibrating and validating linked models; addressing the science issues that arise when models are linked; extending the range of modelling concepts that can be linked; enabling interface standards to pass uncertainty information; making the interface standards platform independent; extending the range of platforms to include those for high performance computing; developing the concept of modelling components as web services; separating simulation code from the model’s GUI, so that all the results from the linked models can be viewed through a single GUI; developing scenario management systems so that that there is an audit trail of the version of each model and dataset used in each linked model run. In addition to the above, there is a need to build a set of integrated

  6. Global Coordination: What are the Next Steps? (United States)

    Spergel, David; Williams, Robert


    From the transit expeditions of 1761 to JWST, ALMA, and the SKA, international projects have played an important role in driving astronomy and heliophysics. Over the past two decades, the increasing complexity and cost of new facilities, the constrained amount of funding available from individual sources, and the rapidly increasing volume of data produced by newer facilities have made international collaboration on large ground- and space-based facilities essential to moving the fields forward. As international cooperation becomes commonplace, data-sharing policies have become ever more important. All IAU members have a stake in the policy decisions made by nations and various scientific consortiums concerning data access and international collaborations. This focus meeting provided a forum to discuss how to improve coordination of global strategic planning in astronomy, astrophysics, and heliophysics in order to maximize the scientific return from research facilities.

  7. Virtualization, The next step for online services

    Directory of Open Access Journals (Sweden)

    Haller Piroska


    Full Text Available Virtualization allows sharing and allocating the hardware resources to more virtual machines thus increasing their usage rate. There are multiple solutions available today such as VMware vSphere, Microsoft Hyper-V, Xen Server and Red Hat KVM each with its own advantages and disadvantages. Choosing the right virtualization solution largely depends on the used applications and their resources requirements. The comparative analysis of the available virtualization solutions shows that it is essential to establish performance criteria’s and minimum and maximum resources usage thresholds over a given period of time. The coexistence of different services in different virtual machines that use different amount of resources allows a more efficient use of the available hardware resources.

  8. Embodied cognition: Taking the next step

    Directory of Open Access Journals (Sweden)

    Roel M Willems


    Full Text Available Recent years have seen a large amount of empirical studies related to ‘embodied cognition’. While interesting and valuable, there is something dissatisfying with the current state of affairs in this research domain. Hypotheses tend to be underspecified, testing in general terms for embodied versus disembodied processing. The lack of specificity of current hypotheses can easily lead to an erosion of the embodiment concept, and result in a situation in which essentially any effect is taken as positive evidence. Such erosion is not helpful to the field and does not do justice to the importance of embodiment. Here we want to take stock, and formulate directions for how it can be studied in a more fruitful fashion. As an example we will describe few example studies that have investigated the role of sensori-motor systems in the coding of meaning (‘embodied semantics’. Instead of focusing on the dichotomy between embodied and disembodied theories, we suggest that the field move forward and ask how and when sensori-motor systems and behavior are involved in cognition.

  9. Combined SRCT & FXCT - The next steps (United States)

    Hall, C.; Acres, R. G.; Winnett, A.; Wang, F.


    One of the goals in developing synchrotron radiation x-ray computed tomography (SRCT) for biomedical specimens, is allowing particular tissues and cell types to be marked in the images. This is equivalent to the staining in histology, which enables researchers to visualise and measure tissue structure and biochemical processes within the specimen. Some progress in this direction for SRCT is being made, using a variety of contrast agents that alter the natural x-ray attenuation of the marked tissue [1]. However there are limits to the usefulness of these attenuation altering techniques. Often high concentrations of potentially disruptive chemicals are required with reduced compatibility for in-vivo studies. Another image highlighting technique which might prove more sensitive is x-ray fluorescence imaging. In this case usually endogenous elemental markers are visualised. We would like to develop a lower resolution, but wider field of view means of three-dimensional (3-D) fluorescence imaging compatible with SRCT. We have previously proposed a technique in which x-ray fluorescence CT (FXCT) and SRCT data can be collected simultaneously [2]. This work resulted in proof of concept modelling, and a simple experiment test system. We show data here which demonstrate a two-dimensional (2-D) reconstruction of an iodine fluorescence map from a phantom. Measurements were performed with a fixed beam modulating mask using the Imaging and Medical beam line (IMBL) at the Australian Synchrotron. Fluorescence data was obtained during a CT scan using a single point detector, while transmission data was simultaneously collected using an area detector. A maximum likelihood expectation maximisation (MLEM) iterative algorithm was used to reconstruct the fluorescence map. We report on technique development and now believe compressive sensing (CS) imaging techniques suit SRCT and may overcome the issues encountered so far in combining SRCT and FXCT.

  10. Development and evaluation of plasma facing materials for future thermonuclear fusion reactors

    Energy Technology Data Exchange (ETDEWEB)

    Linke, J.; Pintsuk, G.; Roedig, M.; Schmidt, A.; Thomser, C. [Forschungszentrum Juelich GmbH, EURATOM Association, Juelich (Germany)


    More and more attention is directed towards thermonuclear fusion as a possible future energy source. Major advantages of this energy conversion technology are the almost inexhaustible resources and the option to produce energy without CO{sub 2}-emissions. However, in the most advanced field of magnetic plasma confinement a number of technological challenges have to be met. In particular high-temperature resistant and plasma compatible meterials have to be developed and qualified which are able to withstand the extreme environments in a commercial thermonuclear power reactor. The plasma facing materials (PEMs) and components (PFCs) in such fusion devices, i.e. the first wall (FW), the limiters and the divertor, are strongly affected by the plasma wall interaction processes and the applied intense thermal loads during plasma operation. On the one hand, these mechanisms have a strong influence on the plasma performance; on the other hand, they have major impact on the lifetime of the plasma facing armour. Materials for plasma facing components have to fulfill a number of requirements. First of all the materials have to be plasma compatible, i.e. they should exhibit a low atomic number to avoid radiative losses whenever atoms from the wall material will be ionized in the plasma. In addition, the materials must have a high melting point, a high thermal conductivity, and adequate mechanical properties. To select the most suitable material candidates, a comprehensive data base is required which includes all thermo-physical and mechanical properties. In present-day and next step devices the resulting thermal steady state heat loads to the first wall remain below 1 MWm{sup -2}, meanwhile the limiters and the divertor are expected to be exposed to power densities being at least one order of magnitude above the FW-level, i.e. up to 20 MWm{sup -2} for next step tokamaks such as ITER or DEMO. These requirements are responsible for high demands on the selection of qualified PFMs

  11. The Next Step: LogoWriter. (United States)

    Papert, Seymour


    Describes features and uses of LogoWriter, a revised and expanded version of Logo. With LogoWriter, a student can not only command the turtle to draw pictures but also (because of a built-in word processor) can add text to the screen. (JN)

  12. Doctor of Professional Counseling: The Next Step (United States)

    Southern, Stephen; Cade, Rochelle; Locke, Don W.


    Professional doctorates have been established in the allied health professions by clinicians seeking the highest levels of independent practice. Allied health professional doctorates include nursing practice (DNP), occupational therapy (OTD), psychology (PsyD), social work (DSW), and marriage and family therapy (DMFT). Lessons learned from the…

  13. Thermonuclear inverse magnetic pumping power cycle for stellarator reactor (United States)

    Ho, Darwin D.; Kulsrud, Russell M.


    The plasma column in a stellarator is compressed and expanded alternatively in minor radius. First a plasma in thermal balance is compressed adiabatically. The volume of the compressed plasma is maintained until the plasma reaches a new thermal equilibrium. The plasma is then expanded to its original volume. As a result of the way a stellarator works, the plasma pressure during compression is less than the corresponding pressure during expansion. Therefore, negative work is done on the plasma over a complete cycle. This work manifests itself as a back-voltage in the toroidal field coils. Direct electrical energy is obtained from this voltage. Alternatively, after the compression step, the plasma can be expanded at constant pressure. The cycle can be made self-sustaining by operating a system of two stellarator reactors in tandem. Part of the energy derived from the expansion phase of a first stellarator reactor is used to compress the plasma in a second stellarator reactor.

  14. FROM THE HISTORY OF PHYSICS: Thermonuclear detonation (United States)

    Feoktistov, L. P.


    The characteristics of, and energy transfer mechanisms involved in, thermonuclear detonation are discussed. What makes the fundamental difference between thermonuclear and chemical detonation is that the former has a high specific energy release and can therefore be employed for preliminarily compressing the thermonuclear mixture ahead of the burning wave. Consequently, with moderate (megajoule) initiation energies, a steady-state detonation laboratory experiment with unlimited energy multiplication becomes a possibility.

  15. APPLICATIONS OF LASERS AND OTHER TOPICS IN LASER PHYSICS AND TECHNOLOGY: Hybrid reactor based on laser thermonuclear fusion (United States)

    Basov, N. G.; Belousov, N. I.; Grishunin, P. A.; Kalmykov, Yu K.; Lebo, I. G.; Rozanov, Vladislav B.; Sklizkov, G. V.; Subbotin, V. I.; Finkel'shteĭn, K. I.; Kharitonov, V. V.; Sherstnev, K. B.


    A physicotechnical and parametric analysis is used as the basis for a conceptual design of a thermonuclear inertial-confinement hybrid reactor as a breeder of fuel for fission nuclear power stations. It is proposed to use a laser as a driver in this reactor.

  16. Multi-User Interactive TV: the Next Step in Personalization

    NARCIS (Netherlands)

    van Brandenburg, Ray; van Deventer, M. Oskar; Karagiannis, Georgios; Schenk, Mike


    In the past few years there has been an increasing trend towards personalization in the TV world. IMS-based IPTV is a good example of a highly personalized IPTV architecture, featuring an advanced identity management subsystem. This article studies a next step in the personalization of the

  17. Draft program plan for TNS: The Next Step after the Tokamak Fusion Test Reactor. Part II. R and D needs assessment

    Energy Technology Data Exchange (ETDEWEB)

    Roberts, M.


    The information contained in this document represents the brief but intensive efforts of the Oak Ridge TNS Program Team to answer the following questions: (1) Is there an adequate basis of R and D support for the TNS program as a central, ambitious goal for the fusion program. (2) What are the principal gaps in the current and projected R and D program. (3) What must be done to permit operation of TNS in the mid 1980s. The findings of our preliminary study provide these answers to the questions: (1) The physics and technology base does exist from which to start the TNS design as a central fusion program goal. (2) We have specific recommendations for new emphasis in certain physics and technology areas to minimize R and D program gaps. (3) TNS conceptual design must be started now, and a close look at organizing the fusion program around a TNS project is an essential need to support operation in the mid 1980s.

  18. Methodology on the sparger development for Korean next generation reactor

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Hwan Yeol; Hwang, Y.D.; Kang, H.S.; Cho, B.H.; Park, J.K


    In case of an accident, the safety depressurization system of Korean Next Generation Reactor (KNGR) efficiently depressurize the reactor pressure by directly discharge steam of high pressure and temperature from the pressurizer into the in-containment refuelling water storage tank (IRWST) through spargers. This report was generated for the purpose of developing the sparger of KNGR. This report presents the methodology on application of ABB-Atom. Many thermal hydraulic parameters affecting the maximum bubble could pressure were obtained and the maximum bubble cloud pressure transient curve so called forcing function of KNGR was suggested and design inputs for IRWST (bubble cloud radius vs. time, bubble cloud velocity vs. time, bubble cloudacceleration vs. time, etc.) were generated by the analytic using Rayleigh-Plesset equation. (author). 17 refs., 6 tabs., 27 figs.

  19. Analysis of design strategies for mitigating the consequences of lithium fire within containment of controlled thermonuclear reactors

    Energy Technology Data Exchange (ETDEWEB)

    Dube, D A; Kazimi, M S


    A lithium combustion model (LITFIRE) was developed to describe the physical and chemical processes which occur during a hypothetical lithium spill and fire. The model was used to study the effectiveness of various design strategies for mitigating the consequences of lithium fire, using the UWMAK-III features as a reference design. Calculations show that without any special fire protection measures, the containment may reach pressures of up to 32 psig when one coolant loop is spilled inside the reactor building. Temperatures as high as 2000/sup 0/F would also be experienced by some of the containment structures. These consequences were found to diminish greatly by the incorporation of a number of design strategies including initially subatmospheric containment pressures, enhanced structural surface heat removal capability, initially low oxygen concentrations, and active post-accident cooling of the containment gas. The EBTR modular design was found to limit the consequences of a lithium spill, and hence offers a potential safety advantage. Calculations of the maximum flame temperature resulting from lithium fire indicate that none of the radioactive first wall materials under consideration would vaporize, and only a few could possibly melt.

  20. The next step in biology: a periodic table? (United States)

    Dhar, Pawan K


    Systems biology is an approach to explain the behaviour of a system in relation to its individual components. Synthetic biology uses key hierarchical and modular concepts of systems biology to engineer novel biological systems. In my opinion the next step in biology is to use molecule-to-phenotype data using these approaches and integrate them in the form a periodic table. A periodic table in biology would provide chassis to classify, systematize and compare diversity of component properties vis-a-vis system behaviour. Using periodic table it could be possible to compute higher- level interactions from component properties. This paper examines the concept of building a bio-periodic table using protein fold as the fundamental unit.

  1. The Development of the Advanced Light Water Reactor in Korea - The Korean Next Generation Reactor -

    Energy Technology Data Exchange (ETDEWEB)

    Kim, H.G.; Park, Y.S.; Kim, B.S.; Cho, S.J. [Korea Electric Power Research Institute, Taejon (Korea)


    Korean next generation reactor (KNGR), which is to be designed as a standard evolutionary advanced light water reactor (ALWR) in Korea, has been developed from 1992 as one of long-term government projects. The major characteristics of the KNGR are as follows; KNGR is 2-loop PWR and its design lift time is 60 years. The CDF and the CFF will be much lower than 10{sup -5}/RY and 10{sup -6}/RY, respectively. For the design improvement, KNGR adopted inconel-690 as a steam generator tube material, four train ECCS, refueling water storage tank inside containment, and double cylindrical concrete containment. For more reliable and easier control, compact workstations have been adopted in the design of main control complex and digital I and C technology is used for protection, control, and monitoring. In addition, KNGR has some passive design features such as fluidic device in safety injection tank, passive secondary condensing system, and passive auto-catalytic hydrogen recombiner to enhance safety. (author). 4 refs., 4 figs.

  2. Agroforestry—The Next Step in Sustainable and Resilient Agriculture

    Directory of Open Access Journals (Sweden)

    Matthew Heron Wilson


    Full Text Available Agriculture faces the unprecedented task of feeding a world population of 9 billion people by 2050 while simultaneously avoiding harmful environmental and social effects. One effort to meet this challenge has been organic farming, with outcomes that are generally positive. However, a number of challenges remain. Organic yields lag behind those in conventional agriculture, and greenhouse gas emissions and nutrient leaching remain somewhat problematic. In this paper, we examine current organic and conventional agriculture systems and suggest that agroforestry, which is the intentional combination of trees and shrubs with crops or livestock, could be the next step in sustainable agriculture. By implementing systems that mimic nature’s functions, agroforestry has the potential to remain productive while supporting a range of ecosystem services. In this paper, we outline the common practices and products of agroforestry as well as beneficial environmental and social effects. We address barriers to agroforestry and explore potential options to alter policies and increase adoption by farmers. We conclude that agroforestry is one of the best land use strategies to contribute to food security while simultaneously limiting environmental degradation.

  3. A next-generation reactor concept: The Integral Fast Reactor (IFR)

    Energy Technology Data Exchange (ETDEWEB)

    Chang, Y.I.


    The Integral Fast Reactor (IFR) is an advanced liquid metal reactor concept being developed at Argonne National Laboratory as reactor technology for the 21st century. It seeks to specifically exploit the inherent properties of liquid metal cooling and metallic fuel in a way that leads to substantial improvements in the characteristics of the complete reactor system, in particular passive safety and waste management. The IFR concept consists of four technical features: (1) liquid sodium cooling, (2) pool-type reactor configuration, (3) metallic fuel, and (4) fuel cycle closure based on pyroprocessing.

  4. A next-generation reactor concept: The Integral Fast Reactor (IFR)

    Energy Technology Data Exchange (ETDEWEB)

    Chang, Y.I.


    The Integral Fast Reactor (IFR) is an advanced liquid metal reactor concept being developed at Argonne National Laboratory as reactor technology for the 21st century. It seeks to specifically exploit the inherent properties of liquid metal cooling and metallic fuel in a way that leads to substantial improvements in the characteristics of the complete reactor system, in particular passive safety and waste management. The IFR concept consists of four technical features: (1) liquid sodium cooling, (2) pool-type reactor configuration, (3) metallic fuel, and (4) fuel cycle closure based on pyroprocessing.

  5. The NASA Evolutionary Xenon Thruster (NEXT): NASA's Next Step for U.S. Deep Space Propulsion (United States)

    Schmidt, George R.; Patterson, Michael J.; Benson, Scott W.


    NASA s Evolutionary Xenon Thruster (NEXT) project is developing next generation ion propulsion technologies to enhance the performance and lower the costs of future NASA space science missions. This is being accomplished by producing Engineering Model (EM) and Prototype Model (PM) components, validating these via qualification-level and integrated system testing, and preparing the transition of NEXT technologies to flight system development. The project is currently completing one of the final milestones of the effort, that is operation of an integrated NEXT Ion Propulsion System (IPS) in a simulated space environment. This test will advance the NEXT system to a NASA Technology Readiness Level (TRL) of 6 (i.e., operation of a prototypical system in a representative environment), and will confirm its readiness for flight. Besides its promise for upcoming NASA science missions, NEXT may have excellent potential for future commercial and international spacecraft applications.

  6. Material challenges for the next generation of fission reactor systems

    Energy Technology Data Exchange (ETDEWEB)

    Buckthorpe, Derek [AMEC, Knutsford, Cheshire (United Kingdom)


    The new generation of fission reactor systems wil require the deployment and construction of a series of advanced water cooled reactors as part of a package of measures to meet UK and European energy needs and to provide a near term non-fossil fuel power solution that addresses CO{sub 2} emission limits. In addition new longer term Generation IV reactor tye systems are being developed and evaluated to enhance safety, reliability, sustainability economics and proliferation resistance requirements and to meet alternative energy applications (outside of electricity generation) such as process heat and large scale hydrogen generation. New fission systems will impose significant challenges on materials supply and development. In the near term, because of the need to 'gear up' to large scale construction after decades of industrial hibernation/contraction and, in the longer term, because of the need for materials to operate under more challenging environments requiring the deployment and development of new alternative materials not yet established to an industrial stage. This paper investigates the materials challenges imposed by the new Generation III+ and Generation IV systems. These include supply and fabrication issues, development of new high temperature alloys and non-metallic materials, the use of new methods of manufacture and the best use of currently available resources and minerals. Recommendations are made as to how these materials challenges might be met and how governments, industry, manufacturers and researchers can all play their part. (orig.)

  7. Next-Step Spherical Torus Experiment and Spherical Torus Strategy in the Fusion Energy Development Path

    Energy Technology Data Exchange (ETDEWEB)

    M. Ono; M. Peng; C. Kessel; C. Neumeyer; J. Schmidt; J. Chrzanowski; D. Darrow; L. Grisham; P. Heitzenroeder; T. Jarboe; C. Jun; S. Kaye; J. Menard; R. Raman; T. Stevenson; M. Viola; J. Wilson; R. Woolley; I. Zatz


    A spherical torus (ST) fusion energy development path which is complementary to proposed tokamak burning plasma experiments such as ITER is described. The ST strategy focuses on a compact Component Test Facility (CTF) and higher performance advanced regimes leading to more attractive DEMO and Power Plant scale reactors. To provide the physics basis for the CTF an intermediate step needs to be taken which we refer to as the ''Next Step Spherical Torus'' (NSST) device and examine in some detail herein. NSST is a ''performance extension'' (PE) stage ST with the plasma current of 5-10 MA, R = 1.5 m, and Beta(sub)T less than or equal to 2.7 T with flexible physics capability. The mission of NSST is to: (1) provide a sufficient physics basis for the design of CTF, (2) explore advanced operating scenarios with high bootstrap current fraction/high performance regimes, which can then be utilized by CTF, DEMO, and Power Plants, and (3) contribute to the general plasma/fusion science of high beta toroidal plasmas. The NSST facility is designed to utilize the Tokamak Fusion Test Reactor (or similar) site to minimize the cost and time required for the design and construction.

  8. The application of computers to controlled thermonuclear research. A report to the USAEC Division of Controlled Thermonuclear Research

    Energy Technology Data Exchange (ETDEWEB)

    Miller, Bennett; Dawson, John; Dory, Robert; Fernbach, Sidney; Goldstein, Max; Hogan, John; Killeen, John; Lazarus, Roger; Leith, Cecil; Nielson, Clair; Rose, Milton; Rutherford, Paul, Taylor, Clyde; Wakefield, Kenneth; Weitzner, Harold


    This report surveys the need for large computers in analyzing the properties of magnetically confined plasmas and simulating the characteristics of fusion reactors. The major conclusion of the report is that, to meet the program schedule developed by Magnetic Confinement Systems, it would be necessary to immediately scale up the CTR (controlled thermonuclear research) computerized effort to a level of two Class IV computers by FY 1975. Based on this report, and in an attempt to best meet this need, it was decided to establish the National CTR Computer Center at the Lawrence Livermore Laboratory.

  9. Lunar Station: The Next Logical Step in Space Development (United States)

    Pittman, Robert Bruce; Harper, Lynn; Newfield, Mark; Rasky, Daniel J.


    The International Space Station (ISS) is the product of the efforts of sixteen nations over the course of several decades. It is now complete, operational, and has been continuously occupied since November of 20001. Since then the ISS has been carrying out a wide variety of research and technology development experiments, and starting to produce some pleasantly startling results. The ISS has a mass of 420 metric tons, supports a crew of six with a yearly resupply requirement of around 30 metric tons, within a pressurized volume of 916 cubic meters, and a habitable volume of 388 cubic meters. Its solar arrays produce up to 84 kilowatts of power. In the course of developing the ISS, many lessons were learned and much valuable expertise was gained. Where do we go from here? The ISS offers an existence proof of the feasibility of sustained human occupation and operations in space over decades. It also demonstrates the ability of many countries to work collaboratively on a very complex and expensive project in space over an extended period of time to achieve a common goal. By harvesting best practices and lessons learned, the ISS can also serve as a useful model for exploring architectures for beyond low-­- earth-­-orbit (LEO) space development. This paper will explore the concept and feasibility for a Lunar Station. The Station concept can be implemented by either putting the equivalent capability of the ISS down on the surface of the Moon, or by developing the required capabilities through a combination of delivered materials and equipment and in situ resource utilization (ISRU). Scenarios that leverage existing technologies and capabilities as well as capabilities that are under development and are expected to be available within the next 3-­5 years, will be examined. This paper will explore how best practices and expertise gained from developing and operating the ISS and other relevant programs can be applied to effectively developing Lunar Station.

  10. The Next Step in the Evolution of the RBV

    DEFF Research Database (Denmark)

    Foss, Kirsten; Foss, Nicolai Juul


    This essay addresses the role of transaction cost economics (TCE) inadvancing the resource-based view. In particular, it is argued that TCE hasthe potential to remedy a number of weak spots in the RBV, such as theabsence of attention in the RBV to the interaction between value creation andvalue...

  11. JIMM: the next step for mission-level models (United States)

    Gump, Jamieson; Kurker, Robert G.; Nalepka, Joseph P.


    The (Simulation Based Acquisition) SBA process is one in which the planning, design, and test of a weapon system or other product is done through the more effective use of modeling and simulation, information technology, and process improvement. This process results in a product that is produced faster, cheaper, and more reliably than its predecessors. Because the SBA process requires realistic and detailed simulation conditions, it was necessary to develop a simulation tool that would provide a simulation environment acceptable for doing SBA analysis. The Joint Integrated Mission Model (JIMM) was created to help define and meet the analysis, test and evaluation, and training requirements of a Department of Defense program utilizing SBA. Through its generic nature of representing simulation entities, its data analysis capability, and its robust configuration management process, JIMM can be used to support a wide range of simulation applications as both a constructive and a virtual simulation tool. JIMM is a Mission Level Model (MLM). A MLM is capable of evaluating the effectiveness and survivability of a composite force of air and space systems executing operational objectives in a specific scenario against an integrated air and space defense system. Because MLMs are useful for assessing a system's performance in a realistic, integrated, threat environment, they are key to implementing the SBA process. JIMM is a merger of the capabilities of one legacy model, the Suppressor MLM, into another, the Simulated Warfare Environment Generator (SWEG) MLM. By creating a more capable MLM, JIMM will not only be a tool to support the SBA initiative, but could also provide the framework for the next generation of MLMs.

  12. A survey on the human reliability analysis methods for the design of Korean next generation reactor

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Yong Hee; Lee, J. W.; Park, J. C.; Kwack, H. Y.; Lee, K. Y.; Park, J. K.; Kim, I. S.; Jung, K. W


    Enhanced features through applying recent domestic technologies may characterize the safety and efficiency of KNGR(Korea Next Generation Reactor). Human engineered interface and control room environment are expected to be beneficial to the human aspects of KNGR design. However, since the current method for human reliability analysis is not up to date after THERP/SHARP, it becomes hard to assess the potential of human errors due to both of the positive and negative effect of the design changes in KNGR. This is a state of the art report on the human reliability analysis methods that are potentially available for the application to the KNGR design. We surveyed every technical aspects of existing HRA methods, and compared them in order to obtain the requirements for the assessment of human error potentials within KNGR design. We categorized the more than 10 methods into the first and the second generation according to the suggestion of Dr. Hollnagel. THERP was revisited in detail. ATHEANA proposed by US NRC for an advanced design and CREAM proposed by Dr. Hollnagel were reviewed and compared. We conclude that the key requirements might include the enhancement in the early steps for human error identification and the quantification steps with considerations of more extended error shaping factors over PSFs(performance shaping factors). The utilization of the steps and approaches of ATHEANA and CREAM will be beneficial to the attainment of an appropriate HRA method for KNGR. However, the steps and data from THERP will be still maintained because of the continuity with previous PSA activities in KNGR design.

  13. The FREYA project at VENUS-F - the next step towards MYRRHA

    Energy Technology Data Exchange (ETDEWEB)

    Krasa, A.; Baeten, P.; Kochetkov, A.; Uyttenhove, W.; Vittiglio, G.; Wagemans, J. [SCK.CEN, Boeretang 200, 2400 Mol (Belgium); Mercatali, L. [Karlsruhe Institute of Technology, Eggenstein-Leopoldshafen (Germany); Bianchini, G.; Carta, M.; Fabrizio, V.; Peluso, V. [ENEA, C.R. Casaccia, via Anguillarese, 301-00060 S. Maria di Galeria (Italy)


    The VENUS-F reactor is a fast, zero-power research reactor. Since 2009 it has used 30% wt. metallic uranium as fuel and solid lead as reflector and coolant simulator. It can also be coupled to a particle accelerator with a neutron producing target and make up a subcritical Accelerator Driven System (ADS). Within the currently ongoing FREYA project, the main tasks being investigated are the validation of online reactivity monitoring of an ADS, the validation of nuclear data and neutronic codes, and the experimental characterization of fast critical and subcritical cores representative for MYRRHA. MYRRHA will be an ADS demonstrator with the option to be operated in critical mode too. So far the only critical core at VENUS-F was assembled using 97 fuel assemblies, each of them consisting of 9 U and 16 Pb rodlets. The core was thoroughly characterized: flux traverses, spectral indices, control rod worth, delayed neutron parameters were measured and compared with Monte Carlo and deterministic calculations. A sensitivity study was also performed focusing on the influence of material impurities, positioning uncertainties, structures and detectors around the core. It was a simple core without any perturbations in the active zone. In the next critical cores that are planned to be investigated in 2015 and 2016, additional elements will be introduced in order to become more representative for MYRRHA. As MYRRHA will use MOX fuel, oxygen will be added into the following core. This will be done by introducing Al{sub 2}O{sub 3} into the fuel assemblies. New fuel assemblies have been already made and are ready to be loaded. Each consists of 13 U, 8 Pb, and 4 Al{sub 2}O{sub 3} rodlets. The new critical core will consist of approximately 40 such fuel assemblies and will be loaded in January 2015. The first results of the characterization measurements will be presented. Additionally, it is planned to investigate coolant void effects. As MYRRHA will be a rather complex system using a

  14. CTB: Next steps

    Energy Technology Data Exchange (ETDEWEB)

    Epstein, W.


    The arms control world has focused on finally achieving the Comprehensive Nuclear Test Ban (CTB) Treaty, a task that was accomplished in September with great agony. Completion of the treaty was welcome news. But it is a flawed instrument in that India a {open_quotes}threshold{close_quotes} nuclear weapon state, has said that it will never sign it. Ultimately that could be fatal to the treaty because India is one of the 44 states that must ratify it before it can enter into force. However, It is possible that India might sign and ratify the CTB within a few years, if the nuclear weapon states get serious about the nuclear disarmament commitment they made more than 25 years ago in Article VI of the Nuclear Non-Proliferation Treaty (NPT), and if the CTB is amended to meet India`s objections. Despite uncertainties regarding the long-range fate of the treaty, the CTB has immediate value. The Vienna Law of Treaties provides that signatories to a treaty must {open_quotes}refrain from acts which would defeat the object and purposes{close_quotes} of the treaty, pending its entry into force. In short, no nuclear tests.

  15. Next Steps in Syria (United States)


    and September 2012. 5 Cited by Deutsche Presse-Agentur, September 16, 2013, but not seen in any other press report. 6 Jason Rezaian, “Iranian...include Shi’a components as well. 11 Anne Barnard, “In Syrian Victory, Hezbollah Risks Broader Fight,” The New York Times, June 6, 2013, A1; Karl

  16. Set of benchmark experiments on slit shielding compositions of thermonuclear reactors

    Energy Technology Data Exchange (ETDEWEB)

    Andreev, M.I.; Afanasiev, V.V.; Belevitin, A.G.; Karaulov, A.V.; Romodanov, V.L. E-mail:; Sakharov, V.K.; Tikhomirov, G.V.; Vasiliev, A.P.; Kandiev, Ya. Z.; Lyutov, V.D.; Sokolov, Yu. A.; Terekhin, V.A.; Shmakov, V.M.; Androsenko, P.A.; Semenov, V.P.; Trykov, L.A.; Lopatkin, A.V.; Muratov, V.G


    The paper is based on the results of the ISTC project no. 180 that has recently been completed. The aim of the project was the development of methodical, hardware and design basis to carry out computational and experimental research on non-uniform shieldings of thermonuclear reactors. As a result a set of benchmark experiments were created. On their basis verification of the domestic and foreign computational codes with the nuclear data estimated was realized. For these purposes the iron hollow slits shielding compositions irradiated with 14.8 MeV energy neutrons were studied. The experimental installations allowed research of the shielding compositions with the following characteristics: a solid structure, a structure with one slit of a central symmetry, and the structures with asymmetric slits and with two slits. The thickness of shielding compositions in this research was 500 mm. The results of experiments were compared to the results of calculations by means of the MCNP-4a and PRIZMA computing codes with use of the FENDL-1.1, FENDL-2, JENDL-3.2 and BAS-78 libraries of nuclear data. The results of comparison made it possible to obtain the recommendations for use of these nuclear data.

  17. Bulk-bronzied graphites for plasma-facing components in ITER (International Thermonuclear Experimental Reactor)

    Energy Technology Data Exchange (ETDEWEB)

    Hirooka, Y.; Conn, R.W.; Doerner, R.; Khandagle, M. (California Univ., Los Angeles, CA (USA). Inst. of Plasma and Fusion Research); Causey, R.; Wilson, K. (Sandia National Labs., Livermore, CA (USA)); Croessmann, D.; Whitley, J. (Sandia National Labs., Albuquerque, NM (USA)); Holland, D.; Smolik, G. (Idaho National Engineering Lab., Idaho Falls, ID (USA)); Matsuda, T.; Sogabe, T. (Toyo Tanso Co. Ltd., O


    Newly developed bulk-boronized graphites and boronized C-C composites with a total boron concentration ranging from 1 wt % to 30 wt % have been evaluated as plasma-facing component materials for the International Thermonuclear Experimental Reactor (ITER). Bulk-boronized graphites have been bombarded with high-flux deuterium plasmas at temperatures between 200 and 1600{degree}C. Plasma interaction induced erosion of bulk-boronized graphites is observed to be a factor of 2--3 smaller than that of pyrolytic graphite, in regimes of physical sputtering, chemical sputtering and radiation enhanced sublimation. Postbombardment thermal desorption spectroscopy indicates that bulk-boronized graphites enhance recombinative desorption of deuterium, which leads to a suppression of the formation of deuterocarbon due to chemical sputtering. The tritium inventory in graphite has been found to decrease by an order of magnitude due to 10 wt % bulk-boronization at temperatures above 1000{degree}C. The critical heat flux to induce cracking for bulk-boronized graphites has been found to be essentially the same as that for non-boronized graphites. Also, 10 wt % bulk-boronization of graphite hinders air oxidation nearly completely at 800{degree}C and reduces the steam oxidation rate by a factor of 2--3 at around 1100 and 1350{degree}C. 38 refs., 5 figs.

  18. The cost management organization: the next step for materiel management. (United States)

    Schuweiler, R C


    With Materiel Management's transition over the last decade from simple logistics to analysis and cost management, it has gained recognition as a key part of the management team responsible for supplies, equipment, standards, and associated processes to identify, purchase, store, distribute, issue, and dispose of supplies and equipment. The materiel manager's job consists of putting the right product in the right place at the right time and in the right quantity at the best total delivered cost. In this context, Materiel Management has made powerful impacts to lower costs associated with: Distribution--costs have been lowered by actively adopting advanced supply channel management techniques such as primary suppliers, JIT, stockless programs, case cart/custom kit/procedure based delivery systems, modified stockless programs as well as margin management through cost plus, flat fee, or margins paid per activity. Cost of goods--lowered through aggregated purchasing in the forms of regional and national purchasing alliances and local capitation or other gain/risk share programs. Internal process costs--lowered by out-sourcing and/or integrating supplier processes and personnel into operations via partnership approaches. We have also reduced transactional costs through EDI transaction sets and the emerging use of the inter and intranet/electronic commerce, procurement cards, and evaluated receipt settlement processes. De-layering--We have lowered the operating costs of Materiel Management overhead by re-design/re-engineering, resulting in reduced management and greater front line authority. Quality--We have learned to identify and respond to customer and supplier needs by using quality improvement tools and ongoing measurement and monitoring techniques. Through this we have identified the waste of non-beneficial products and services. We have adopted supplier certification measurers to ensure quality is built into processes and outcomes. With so much already accomplished

  19. Development of technology for next generation reactor - Development of next generation reactor in Korea -

    Energy Technology Data Exchange (ETDEWEB)

    Park, Jong Kyun; Chang, Moon Heuy; Hwang, Yung Dong [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of)] [and others


    The project, development of next generation reactor, aims overall related technology development and obtainment of related license in 2001. The development direction is to determine the reactor type and to build up the design concept in 1994. For development trend analysis of foreign next generation reactor, level-1 PSA, fuel cycle analysis and computer code development are performed on System 80+ and AP 600. Especially for design characteristics analysis and volume upgrade of AP 600, nuclear fuel and reactor core design analysis, coolant circuit design analysis, mechanical structure design analysis and safety analysis etc. are performed. (Author).

  20. Radiolabeled immunotherapy in non-Hodgkin's lymphoma treatment : the next step

    NARCIS (Netherlands)

    Otte, Andreas; van de Wiele, Christophe; Dierckx, Rudi A.

    Radiolabeled immunotherapy (RIT) is becoming a significant step forward in the treatment management of non-Hodgkin's lymphoma (NHL). In this state-of-the-art review article, general details, practical and health economic aspects, and next steps of RIT in NHL are reviewed from the existing literature

  1. The Next Generation Nuclear Plant/Advanced Gas Reactor Fuel Irradiation Experiments in the Advanced Test Reactor

    Energy Technology Data Exchange (ETDEWEB)

    S. Blaine Grover


    The United States Department of Energy’s Next Generation Nuclear Plant (NGNP) Program will be irradiating eight separate low enriched uranium (LEU) tri-isotopic (TRISO) particle fuel (in compact form) experiments in the Advanced Test Reactor (ATR) located at the Idaho National Laboratory (INL). The ATR has a long history of irradiation testing in support of reactor development and the INL has been designated as the new United States Department of Energy’s lead laboratory for nuclear energy development. The ATR is one of the world’s premiere test reactors for performing long term, high flux, and/or large volume irradiation test programs. These irradiations and fuel development are being accomplished to support development of the next generation reactors in the United States, and will be irradiated over the next ten years to demonstrate and qualify new particle fuel for use in high temperature gas reactors. The goals of the irradiation experiments are to provide irradiation performance data to support fuel process development, to qualify fuel for normal operating conditions, to support development and validation of fuel performance and fission product transport models and codes, and to provide irradiated fuel and materials for post irradiation examination (PIE) and safety testing. The experiments, which will each consist of at least six separate capsules, will be irradiated in an inert sweep gas atmosphere with individual on-line temperature monitoring and control of each capsule. The sweep gas will also have on-line fission product monitoring on its effluent to track performance of the fuel in each individual capsule during irradiation. The first experiment (designated AGR-1) started irradiation in December 2006, and the second experiment (AGR-2) is currently in the design phase. The design of test trains, as well as the support systems and fission product monitoring system that will monitor and control the experiment during irradiation will be discussed. In


    Energy Technology Data Exchange (ETDEWEB)



    Historically, the groundwater monitoring activities at the Department of Energy's Hanford Site in southeastern Washington State have been very "people intensive." Approximately 1500 wells are sampled each year by field personnel or "samplers." These individuals have been issued pre-printed forms showing information about the well(s) for a particular sampling evolution. This information is taken from 2 official electronic databases: the Hanford Well information System (HWIS) and the Hanford Environmental Information System (HEIS). The samplers used these hardcopy forms to document the groundwater samples and well water-levels. After recording the entries in the field, the samplers turned the forms in at the end of the day and other personnel posted the collected information onto a spreadsheet that was then printed and included in a log book. The log book was then used to make manual entries of the new information into the software application(s) for the HEIS and HWIS databases. A pilot project for automating this extremely tedious process was lauched in 2008. Initially, the automation was focused on water-level measurements. Now, the effort is being extended to automate the meta-data associated with collecting groundwater samples. The project allowed electronic forms produced in the field by samplers to be used in a work flow process where the data is transferred to the database and electronic form is filed in managed records - thus eliminating manually completed forms. Elimating the manual forms and streamlining the data entry not only improved the accuracy of the information recorded, but also enhanced the efficiency and sampling capacity of field office personnel.

  3. Taking the Next Step - Implementing a Currency Transaction Development Levy


    Kapoor, Sony; Hillman, David; Spratt, Stephen


    As we approach the half-way point for the achievement of many of the Millennium Development Goals (MDGs) the spotlight is shining ever more intently on the urgent need for new sources of revenue to pay for them. With the first international development duty launched, in the form of the ‘pilot’ solidarity levy on air travel, the momentum needs to continue to the implementation in quick succession of a second such initiative to provide another long term predictable source of addi...

  4. The next step: intelligent digital assistance for clinical operating rooms

    Directory of Open Access Journals (Sweden)

    Miehle Juliana


    Full Text Available With the emergence of new technologies, the surgical working environment becomes increasingly complex and comprises many medical devices that have to be taken cared of. However, the goal is to reduce the workload of the surgical team to allow them to fully focus on the actual surgical procedure. Therefore, new strategies are needed to keep the working environment manageable. Existing research projects in the field of intelligent medical environments mostly concentrate on workflow modeling or single smart features rather than building up a complete intelligent environment. In this article, we present the concept of intelligent digital assistance for clinical operating rooms (IDACO, providing the surgeon assistance in many different situations before and during an ongoing procedure using natural spoken language. The speech interface enables the surgeon to concentrate on the surgery and control the technical environment at the same time, without taking care of how to interact with the system. Furthermore, the system observes the context of the surgery and controls several devices autonomously at the appropriate time during the procedure.

  5. Wind Powering America: The Next Steps in North Carolina

    Energy Technology Data Exchange (ETDEWEB)

    Banks, Jennifer L. [North Carolina Solar Center; Scanlin, Dennis [Appalachian State University; Quinlan, Paul [North Carolina Sustainable Energy Association


    The goal of this project is to apply the WPA’s proactive outreach strategy to the problem of educating the public about the likely transmission infrastructure developments concomitant to the significant development of wind energy resources in North Carolina. Given the lead time to develop significant new transmission infrastructure (5-10 years), it is critical to begin this outreach work today, so that wind resources can be developed to adequately meet the 20% by 2030 goal in the mid- to long-term (10-20 years). The project team planned to develop a transmission infrastructure outreach campaign for North Carolina by: (1) convening a utility interest group (UIG) of the North Carolina Wind Working Group (NC WWG) consisting of electric utilities in the state and the Southeast; and (2) expanding outreach to local and state government officials in North Carolina.

  6. The 2012 School Psychology Futures Conference: Accomplishments and next Steps (United States)

    Jamruz-Smith, Susan; Harrison, Patti L.; Cummings, Jack A.


    The major national and international school psychology organizations hosted the 2012 School Psychology Futures Conference during the fall of 2012. The conference was designed to provide an opportunity for school psychologists to plan their future roles in better supporting children, families, and schools. The 2012 conference, titled "School…

  7. The next step: detailed assessment of an adult glaucoma patient

    Directory of Open Access Journals (Sweden)

    Matthew Burton


    Full Text Available The glaucomas are a group of progressive optic neuropathies associated with characteristic structural changes at the optic nerve head (cupping and corresponding visual field defects. The main modifiable risk factor for glaucomatous optic neuropathy is increased intraocular pressure (IOP. The aims of assessment are:accurate diagnosisidentification of the cause of increased IOP, if applicablequantification of the level of glaucoma damage and functional impairment.

  8. Next Steps in the Evolution of Human Spaceflight Training (United States)

    Balmain, Clint; Niemann, Chris; McGregor, Darrell


    Train before you fly has always been a watchword at NASA, and consequently, NASA has been conducting training for human spaceflight missions for longer than it has been involved in the actual conduct of human spaceflight missions. Throughout that time, NASA s approach to human spaceflight training has continuously evolved to keep pace with the technology of the modern world, but the approach to training itself has not changed significantly. Today, there are more tools and technologies that enable learning than ever before. This paper intends to review the challenges of human spaceflight training and how modern technology and an updated approach could improve that training. The Spaceflight Training Management Office (DA7) within the Mission Operations Directorate (MOD) has been investigating the current training of instructors, flight controllers and astronauts in order to identify where a new approach to training and training management may be necessary to improve the efficacy of the training provided. Through this investigation, the DA7 team has identified potential areas of improvement within International Space Station (ISS) training in a wide range of areas, including the delivery of training, the structure of the training program, the concept of what is considered training, and the management of that training. The ISS is an operational program with an established training paradigm. As such, the implementation of these concepts will be met with several challenges that may prevent or preclude them from being adopted. These challenges include demonstrating return-on-investment (ROI) and overcoming cultural or technological obstacles. This report will delve into the possible improvement areas for training, the future training concepts that are being considered, and the challenges associated with implementation. The paper will include concepts for utilization of Web 2.0 technologies, electronic learning, digital media, and other technologies in the development

  9. The Next Step towards a Function Markup Language

    NARCIS (Netherlands)

    Heylen, Dirk K.J.; Kopp, S.; Marsella, S.C.; Pelachaud, C.; Vilhjálmson, H.; Prendinger, H.; Lester, J.; Ishizuka, M.


    In order to enable collaboration and exchange of modules for generating multimodal communicative behaviours of robots and virtual agents, the SAIBA initiative envisions the definition of two representation languages. One of these is the Function Markup Language (FML). This language specifies the

  10. Three Years After: Next Steps in the War on Terror (United States)


    Vietnam. Mr. Jenkins has a B.A. in fine arts and an M.A. in history, both from UCLA. He studied at the University of Guanajuato in Mexico and in the...hangs over the American economy . Much of the original leadership of al Qaeda remains intact and can communicate publicly as well as clandestinely. A...costs of their violent acts. We should help dramatize their in- ability to govern to the benefit of their societies. For example, in Iran the economy

  11. Progress and Next Steps in the BIOPROTA Collaborative Forum

    Energy Technology Data Exchange (ETDEWEB)

    Perez-Sanchez, Danyl [Departamento de Medio Ambiente, Centro de Investigaciones Energeticas Medioambientales y Tecnologicas - CIEMAT, Avenida Complutense 40, 28040, Madrid (Spain); Smith, G. [GMS Abingdon Ltd, Tamarisk, Radley Road, Abingdon, OX14 3PP (United Kingdom); Smith, K. [RadEcol Consulting Ltd, Fell View, Middletown, Cumbria, CA22 2UG (United Kingdom)


    BIOPROTA is an international collaborative forum, started in 2002, designed to support resolution of key issues in the biosphere aspects of assessments of the long-term impact of potential contaminant releases associated with solid radioactive waste disposal. The focus is on the application of good science to provide a good understanding of relevant biosphere system processes and address important uncertainties. This in turn supports decision making related to waste management and the appropriate allocation of resources to solve problems. Membership includes regulators, operators, technical support organisations and academic institutions from North America, Europe and Asia. Member organisations have representation on a Sponsoring Committee, currently chaired by Danyl Perez-Sanchez (CIEMAT) and supported by a Technical Secretariat. Given the long time frames which are required to be addressed in post-closure assessments of radioactive waste disposal facilities, thousands of years or even longer, the range of assessment issues is very large. In essence, they boil down to being related to the scope for environmental change and the behaviour of humans and ecosystems in response to such change, including their contribution to the change itself. This requires consideration of climate change, landscape evolution, the dynamics of ecosystems, and then, the behaviour of radionuclides within those changing systems and the ways by which their presence may give rise to radiation exposure. It is multi-disciplinary but has an important focus on radioecology. The forum is tailored to enable opportunities for sharing, reviewing and interpretation of information used in assessments. This includes methods for system characterisation and description, modelling of system evolution subject to assumptions for environmental change, exposure modelling according to those possibilities for evolution, and data to support all the assessment assumptions and model parameter selection. The

  12. The Next Step Toward Widespread Residential Deep Energy Retrofits

    Energy Technology Data Exchange (ETDEWEB)

    McIlvaine, J. [Building American Partnership for Residential Construction (BA-PIRC), Cocoa, FL (United States); Martin, E. [Building American Partnership for Residential Construction (BA-PIRC), Cocoa, FL (United States); Saunders, S. [Building American Partnership for Residential Construction (BA-PIRC), Cocoa, FL (United States); Bordelon, E. [Building American Partnership for Residential Construction (BA-PIRC), Cocoa, FL (United States); Baden, S. [Building American Partnership for Residential Construction (BA-PIRC), Cocoa, FL (United States); Elam, L. [Building American Partnership for Residential Construction (BA-PIRC), Cocoa, FL (United States)


    The complexity of deep energy retrofits warrants additional training to successfully manage multiple improvements that will change whole house air, heat, and moisture flow dynamics. The home performance contracting industry has responded to these challenges by aggregating skilled labor for assessment of and implementation under one umbrella. Two emerging business models are profiled that seek to resolve many of the challenges, weaknesses, opportunities, and threats described for the conventional business models.

  13. The requirements of a next step large steady state tokamak (United States)

    Janeschitz, G.; Barabaschi, P.; Federici, G.; Ioki, K.; Ladd, P.; Mukhovatov, V.; Sugihara, M.; Tivey, R.; ITER-JCT; Home Team


    After a decision by the ITER parties to investigate the possibility of designing a reduced cost version of ITER several possible machine layouts with different aspect ratios were studied. Relatively early in this process it became clear that there is no significant cost difference between different aspect ratios and that there is a maximum realistically possible aspect ratio for a machine with 6 m major radius and rather high plasma shaping. Following this study a machine with an intermediate aspect ratio (3.1) called the ITER Fusion Energy Advanced Tokamak (ITER FEAT) was chosen as the basis for the outline design of a reduced cost ITER. Several potential steady state scenarios can be investigated in ITER FEAT, i.e. monotonic or reversed shear at full or reduced minor radius. In addition, so-called hybrid discharges, are feasible where a mixture of inductive and non-inductive current drive as well as bootstrap current allows long pulse discharges of the order of 2500 s. The βN values and H factors required for these discharges are in the same range as those observed on present machines, which provides confidence that such discharges can be studied in ITER FEAT. However, due to uncertainties in physics knowledge, for example the current drive efficiency off-axis, it is impossible at present to generate a completely self-consistent scenario taking all boundary conditions, for example engineering or heating system constraints, into account. In addition, all of these regimes have a potential problem with divertor operation compatibility (low edge density) and with helium exhaust which has to be addressed in existing experiments. For the engineering design of the in-vessel components and for the balance of the plant there is practically no difference between inductive (500 s) and steady state operation. However, the choice of heating systems and the distribution of power between them will be strongly influenced by the envisaged steady state scenarios.

  14. Digital and customized lingual orthodontics: The next step

    Directory of Open Access Journals (Sweden)

    Jignesh Kothari


    Full Text Available There is no doubt that lingual orthodontics offers the most aesthetic solution to treat all kinds of malocclusions with full 3 dimensional control of the dentition & complete invisibility. Unfortunately the lingual approach has always been considered the more difficult and cumbersome way to treat patients. With the introduction of CAD CAM appliances we have reached an era of more predictable treatment planning and execution in lingual orthodontics, thus enabling lingual treatments to be a part of every orthodontic practice in India. Digital planning and customised approach makes lingual orthodontics more user friendly and Predictable.

  15. Translation of Nutritional Genomics into Nutrition Practice: The Next Step. (United States)

    Murgia, Chiara; Adamski, Melissa M


    Genetics is an important piece of every individual health puzzle. The completion of the Human Genome Project sequence has deeply changed the research of life sciences including nutrition. The analysis of the genome is already part of clinical care in oncology, pharmacology, infectious disease and, rare and undiagnosed diseases. The implications of genetic variations in shaping individual nutritional requirements have been recognised and conclusively proven, yet routine use of genetic information in nutrition and dietetics practice is still far from being implemented. This article sets out the path that needs to be taken to build a framework to translate gene-nutrient interaction studies into best-practice guidelines, providing tools that health professionals can use to understand whether genetic variation affects nutritional requirements in their daily clinical practice.

  16. Translation of Nutritional Genomics into Nutrition Practice: The Next Step

    Directory of Open Access Journals (Sweden)

    Chiara Murgia


    Full Text Available Genetics is an important piece of every individual health puzzle. The completion of the Human Genome Project sequence has deeply changed the research of life sciences including nutrition. The analysis of the genome is already part of clinical care in oncology, pharmacology, infectious disease and, rare and undiagnosed diseases. The implications of genetic variations in shaping individual nutritional requirements have been recognised and conclusively proven, yet routine use of genetic information in nutrition and dietetics practice is still far from being implemented. This article sets out the path that needs to be taken to build a framework to translate gene–nutrient interaction studies into best-practice guidelines, providing tools that health professionals can use to understand whether genetic variation affects nutritional requirements in their daily clinical practice.

  17. Translation of Nutritional Genomics into Nutrition Practice: The Next Step (United States)

    Murgia, Chiara; Adamski, Melissa M.


    Genetics is an important piece of every individual health puzzle. The completion of the Human Genome Project sequence has deeply changed the research of life sciences including nutrition. The analysis of the genome is already part of clinical care in oncology, pharmacology, infectious disease and, rare and undiagnosed diseases. The implications of genetic variations in shaping individual nutritional requirements have been recognised and conclusively proven, yet routine use of genetic information in nutrition and dietetics practice is still far from being implemented. This article sets out the path that needs to be taken to build a framework to translate gene–nutrient interaction studies into best-practice guidelines, providing tools that health professionals can use to understand whether genetic variation affects nutritional requirements in their daily clinical practice. PMID:28383492

  18. The next step in biology: A periodic table?

    Indian Academy of Sciences (India)



    Aug 6, 2007 ... In my opinion, a bio-periodic table could be defined as a tabular arrangement of unique biological elements that, in combinations, produce distinct higher-level properties of the system. This paper examines the possibility of using 'protein fold' as building block of a molecular periodic table. Before we delve ...

  19. Colloquial French 2 the next step in language learning

    CERN Document Server

    Broady, Elspeth


    Do you know French already and want to go a stage further? If you're planning a visit to France, need to brush up your French for work, or are simply doing a course, Colloquial French 2 is the ideal way to refresh your knowledge of the language and to extend your skills.Colloquial French 2 is designed to help those involved in self-study, and structured to give you the opportunity to listen to and read lots of modern, everyday French. It has been developed to work systematically on reinforcing and extending your grasp of French grammar and vocabulary.Key features of Colloquial French 2 include

  20. Colloquial French 2 the next step in language learning

    CERN Document Server

    Broady, Elspeth


    Do you know French already and want to go a stage further? If you''re planning a visit to France, need to brush up your French for work, or are simply doing a course, Colloquial French 2 is the ideal way to refresh your knowledge of the language and to extend your skills.Colloquial French 2 is designed to help those involved in self-study, and structured to give you the opportunity to listen to and read lots of modern, everyday French. It has been developed to work systematically on reinforcing and extending your grasp of French grammar and vocabulary.Key features of Colloquial French 2 includ

  1. Nanoformulated antibiotics: the next step for pathogenic bacteria control. (United States)

    Saúde, Amanda Caroline Marques; Cherobim, Mariana Dornelles; Amaral, André Corrêa; Dias, Simoní Campos; Franco, Octávio Luiz


    The resistance of infectious bacteria to current antibiotics is a worldwide problem. Previous studies have demonstrated the efficacy of nanostructured molecules against pathogens as an innovative methodology for the development of novel drugs. Currently, 95% of properties limited pharmacies applicability such as low solubility, short half-life in the circulatory system, toxicity associated to controlled release and immunogenicity. Furthermore, nanobiotechnology provides a different perspective for modifying these properties and allows innovative drug development. In this context, this review aims to describe different methods, polymers, and drugs used to obtain and analyze nanostructures associated with antibiotics as an unconventional and innovative tool for bacterial control. Biotechnology provides a different perspective for modifying drug properties and allows innovative drug development. This review describes nanostructures in association with antibiotics as an unconventional and innovative tool for bacterial control.

  2. E-waste: the growing global problem and next steps. (United States)

    Heacock, Michelle; Kelly, Carol Bain; Suk, William A


    In many low- and middle-income countries, handling and disposal of discarded electrical or electronic equipment (EEE) is frequently unregulated. e-Waste contains hazardous constituents such as lead, mercury, and chromium, certain chemicals in plastics, and flame retardants. There is increasing concern about health effects related to contamination in air, soil, and water for people working and living at or near informal e-waste processing sites, especially to the most vulnerable populations, pregnant women and children. The observed adverse health effects and increasing number of e-waste sites make protecting human health and the environment from e-waste contamination an expanding challenge. Through international cooperation, awareness can be elevated about the harm that e-waste processing poses to human health. Here we discuss how international researchers, public health practitioners, and policymakers can employ solutions to reduce e-waste exposures.

  3. Lymphatic Vascular Regeneration : The Next Step in Tissue Engineering

    NARCIS (Netherlands)

    Huethorst, Eline; Krebber, Merle M; Fledderus, Joost O; Gremmels, Hendrik; Xu, Yan Juan; Pei, Jiayi; Verhaar, Marianne C; Cheng, Caroline


    The lymphatic system plays a crucial role in interstitial fluid drainage, lipid absorption, and immunological defense. Lymphatic dysfunction results in lymphedema, fluid accumulation, and swelling of soft tissues, as well as a potentially impaired immune response. Lymphedema significantly reduces

  4. Working Consumers: The Next Step in Marketing Theory?


    Cova, Bernard; Dalli, Daniele


    In marketing and consumer research, consumers have been increasingly theorised as producers. However, these theorisations do not take all facets of consumers’ productive role into account. This paper mobilises both post-Marxist economics and post-Maussian socio-economics to develop the concept of working consumer. This concept depicts consumers who, through their immaterial labour, add cultural and affective value to market offerings. In so doing consumers increase the value of market offerin...

  5. Sociocultural Systems: The Next Step in Army Cultural Capability (United States)


    Durkheim , and Weber, the correspondence perspective presumes a duality between social structure and culture (ideology) and how culture relates to...Émile Durkheim (1965) has a mimetic conception of religious ideas—they are the symbolic representations of social arrangements. Because religion...its own difficulties. Durkheim is criticized for taking a “reductionistic attitude toward belief in God” (Godlove, 1989, p. 185; see also Phillips

  6. Turing's next steps: the mechanochemical basis of morphogenesis. (United States)

    Howard, Jonathon; Grill, Stephan W; Bois, Justin S


    Nearly 60 years ago, Alan Turing showed theoretically how two chemical species, termed morphogens, diffusing and reacting with each other can generate spatial patterns. Diffusion plays a crucial part in transporting chemical signals through space to establish the length scale of the pattern. When coupled to chemical reactions, mechanical processes - forces and flows generated by motor proteins - can also define length scales and provide a mechanochemical basis for morphogenesis. forces and flows generated by motor proteins - can also define length scales and provide a mechanochemical basis for morphogenesis.

  7. Systems and software quality the next step for industrialisation

    CERN Document Server

    Wieczorek, Martin; Bons, Heinz


    Software and systems quality is playing an increasingly important role in the growth of almost all - profit and non-profit - organisations. Quality is vital to the success of enterprises in their markets. Most small trade and repair businesses use software systems in their administration and marketing processes. Every doctor's surgery is managing its patients using software. Banking is no longer conceivable without software. Aircraft, trucks and cars use more and more software to handle their increasingly complex technical systems. Innovation, competition and cost pressure are always present i

  8. Taking the Next Step: Ways Forward for Coaching Science (United States)

    Abraham, Andrew; Collins, Dave


    Coaching is no longer a subset of physical education or sport psychology but is rather an established vocation for research. In reaching such a position, we argue that a broad range of epistemologies have been used to investigate coaching such as sociology and cognitive psychology. However there is danger that, in the search for new ground,…

  9. Prevention of chronic kidney disease : The next step forward!

    NARCIS (Netherlands)

    de Jong, PE; Gansevoort, RT

    The incidence of end stage renal disease in patients who have not experienced a classic primary renal disease is dramatically increasing. Chronic kidney disease (CKD) in these patients is due to diabetes, mostly type 2, hypertension and generalised atherosclerosis. As these patients are frequently

  10. Blockchain: The Evolutionary Next Step for ICT E-Agriculture

    Directory of Open Access Journals (Sweden)

    Yu-Pin Lin


    Full Text Available Blockchain technology, while still challenged with key limitations, is a transformative Information and Communications Technology (ICT that has changed our notion of trust. Improved efficiencies for agricultural sustainable development has been demonstrated when ICT-enabled farms have access to knowledge banks and other digital resources. UN FAO-recommended ICT e-agricultural infrastructure components are a confluence of ICT and blockchain technology requirements. When ICT e-agricultural systems with blockchain infrastructure are immutable and distributed ledger systems for record management, baseline agricultural environmental data integrity is safeguarded for those who participate in transparent data management. This paper reviewed blockchain-based concepts associated with ICT-based technology. Moreover, a model ICT e-agriculture system with a blockchain infrastructure is proposed for use at the local and regional scale. To determine context specific technical and social requirements of blockchain technology for ICT e-agriculture systems, an evaluation tool is presented. The proposed system and tool can be evaluated and applied to further developments of e-agriculture systems.

  11. Michelangelo initiative. The next generation of reactors. Safety and competitiveness. Innovative Nuclear Reactor Technologies

    Energy Technology Data Exchange (ETDEWEB)

    Zero, S. [Framatome, Paris (France); Von Lensa, W. [Institut fuer Sicherheitsforschung und Reaktortechnik ISR, Forschungszentrum Juelich, Juelich (Germany)


    The MICHELANGELO initiative was launched by the European nuclear industry and by many different research and development (R and D) organizations. It is open to any organization or company that shares a belief in its contents and end purposes. Under the aegis of the European Commission and in the context of the 5th Framework Programme, it aims to encourage a strong partnership of research and industry in the nuclear energy field, with the goal of supporting the safety and competitiveness of future European reactors. This initiative is complemented by the Concerted Action on `Safety-related Innovative Nuclear Reactor Technology Elements - R and D (SINTER) Network` aiming at a similar synergetic approach towards a work-shared European R and D Network. All European R and D actors are invited to submit their proposals for future R and D topics as a bottom-up for a systematic R and D programme configuration. Close interaction between the industry and the R and D side is foreseen to respond effectively on future public and industrial requirements on a European level

  12. Controlled thermonuclear fusion

    CERN Document Server

    Bobin, Jean Louis


    The book is a presentation of the basic principles and main achievements in the field of nuclear fusion. It encompasses both magnetic and inertial confinements plus a few exotic mechanisms for nuclear fusion. The state-of-the-art regarding thermonuclear reactions, hot plasmas, tokamaks, laser-driven compression and future reactors is given.

  13. Preliminary materials selection issues for the next generation nuclear plant reactor pressure vessel.

    Energy Technology Data Exchange (ETDEWEB)

    Natesan, K.; Majumdar, S.; Shankar, P. S.; Shah, V. N.; Nuclear Engineering Division


    In the coming decades, the United States and the entire world will need energy supplies to meet the growing demands due to population increase and increase in consumption due to global industrialization. One of the reactor system concepts, the Very High Temperature Reactor (VHTR), with helium as the coolant, has been identified as uniquely suited for producing hydrogen without consumption of fossil fuels or the emission of greenhouse gases [Generation IV 2002]. The U.S. Department of Energy (DOE) has selected this system for the Next Generation Nuclear Plant (NGNP) Project, to demonstrate emissions-free nuclear-assisted electricity and hydrogen production within the next 15 years. The NGNP reference concepts are helium-cooled, graphite-moderated, thermal neutron spectrum reactors with a design goal outlet helium temperature of {approx}1000 C [MacDonald et al. 2004]. The reactor core could be either a prismatic graphite block type core or a pebble bed core. The use of molten salt coolant, especially for the transfer of heat to hydrogen production, is also being considered. The NGNP is expected to produce both electricity and hydrogen. The process heat for hydrogen production will be transferred to the hydrogen plant through an intermediate heat exchanger (IHX). The basic technology for the NGNP has been established in the former high temperature gas reactor (HTGR) and demonstration plants (DRAGON, Peach Bottom, AVR, Fort St. Vrain, and THTR). In addition, the technologies for the NGNP are being advanced in the Gas Turbine-Modular Helium Reactor (GT-MHR) project, and the South African state utility ESKOM-sponsored project to develop the Pebble Bed Modular Reactor (PBMR). Furthermore, the Japanese HTTR and Chinese HTR-10 test reactors are demonstrating the feasibility of some of the planned components and materials. The proposed high operating temperatures in the VHTR place significant constraints on the choice of material selected for the reactor pressure vessel for

  14. Fusion-power demonstration. [Next step beyond MFTF-B

    Energy Technology Data Exchange (ETDEWEB)

    Henning, C.D.; Logan, B.G.; Carlson, G.A.; Neef, W.S.; Moir, R.W.; Campbell, R.B.; Botwin, R.; Clarkson, I.R.; Carpenter, T.J.


    As a satellite to the MARS (Mirror Advanced Reactor Study) a smaller, near-term device has been scoped, called the FPD (Fusion Power Demonstration). Envisioned as the next logical step toward a power reactor, it would advance the mirror fusion program beyond MFTF-B and provide an intermediate step toward commercial fusion power. Breakeven net electric power capability would be the goal such that no net utility power would be required to sustain the operation. A phased implementation is envisioned, with a deuterium checkout first to verify the plasma systems before significant neutron activation has occurred. Major tritium-related facilities would be installed with the second phase to produce sufficient fusion power to supply the recirculating power to maintain the neutral beams, ECRH, magnets and other auxiliary equipment.

  15. The next step to creating a more efficient form of paperless contracting


    Sweet, Gerald L.


    Joint Applied Project The purpose of this project is to explore the early years of paper-procurement and chart the progression to paperless contracting. This will be followed by the Department of Defense's next step to further improve procurement software and user interface. This will be contrasted against the Army's further refinement of their enterprise system that only removes the paper from the otherwise archaic procurement system. The author, a contracting officer whose background in...

  16. Cryogenic instrumentation needs in the controlled thermonuclear research program

    Energy Technology Data Exchange (ETDEWEB)

    Walstrom, P.L.


    The magnet development effort for the controlled thermonuclear research program will require extensive testing of superconducting coils at various sizes from small-scale models to full-size prototypes. Extensive use of diagnostic instrumentation will be required and to make detailed comparisons of predicted and actual performance in magnet tests and to monitor the test facility for incipient failure modes. At later stages of the program, cryogenic instrumentation will be required to monitor magnet system performance in fusion power reactors. Measured quantities may include temperature, strain, deflection, coil resistance, helium coolant pressure and flow, current, voltages, etc. The test environment, which includes high magnetic fields (up to 8-10 T) and low temperature, makes many commercial measuring devices inoperative or at least inaccurate. In order to ensure reliable measurements, careful screening of commercial devices for performance in the test environment will be required. A survey of potentially applicable instrumentation is presented along with available information on operation in the test environment based on experimental data or on analysis of the physical characteristics of the device. Areas where further development work is needed are delineated.

  17. The LOFT perspective on neutron star thermonuclear bursts

    DEFF Research Database (Denmark)

    in ’t Zand, J.J.M.; Altamirano, D.; Ballantyne, D. R.

    This is a White Paper in support of the mission concept of the Large Observatory for X-ray Timing (LOFT), proposed as a medium-sized ESA mission. We discuss the potential of LOFT for the study of thermonuclear X-ray bursts on accreting neutron stars. For a summary, we refer to the paper....

  18. The gas turbine-modular helium reactor (GT-MHR), high efficiency, cost competitive, nuclear energy for the next century

    Energy Technology Data Exchange (ETDEWEB)

    Zgliczynski, J.B.; Silady, F.A.; Neylan, A.J.


    The Gas Turbine-Modular Helium Reactor (GT-MHR) is the result of coupling the evolution of a small passively safe reactor with key technology developments in the US during the last decade: large industrial gas turbines, large active magnetic bearings, and compact, highly effective plate-fin heat exchangers. The GT-MHR is the only reactor concept which provides a step increase in economic performance combined with increased safety. This is accomplished through its unique utilization of the Brayton cycle to produce electricity directly with the high temperature helium primary coolant from the reactor directly driving the gas turbine electrical generator. This cannot be accomplished with another reactor concept. It retains the high levels of passive safety and the standardized modular design of the steam cycle MHTGR, while showing promise for a significant reduction in power generating costs by increasing plant net efficiency to a remarkable 47%.

  19. Proceedings of the international workshop on engineering design of next step reversed field pinch devices

    Energy Technology Data Exchange (ETDEWEB)

    Thomson, D.B. (comp.)


    These Proceedings contain the formal contributed papers, the workshop papers and workshop summaries presented at the International Workshop on Engineering Design of Next Step RFP Devices held at Los Alamos, July 13-17, 1987. Contributed papers were presented at formal sessions on the topics: (1) physics overview (3 papers); (2) general overview (3 papers); (3) front-end (9 papers); (4) computer control and data acquisition (1 paper); (5) magnetics (5 papers); and (6) electrical design (9 papers). Informal topical workshop sessions were held on the topics: (1) RFP physics (9 papers); (2) front-end (7 papers); (3) magnetics (3 papers); and (4) electrical design (1 paper). This volume contains the summaries written by the Chairmen of each of the informal topical workshop sessions. The papers in these Proceedings represent a significant review of the status of the technical base for the engineering design of the next step RFP devices being developed in the US, Europe, and Japan, as of this date.

  20. Evolution of the Baseline ISS ECLSS Technologies: The Next Logical Steps (United States)

    Carrasquillo, Robyn L.; Bagdigian, Bob; Perry, Jay; Lewis, John; Williams, Dave


    The baseline Environmental Control and Life Support Systems which are currently deployed on the International Space Station or planned to be launched in Node 3 are based on technologies selected in the early 1990's. While they are generally meeting or exceeding requirements for supporting the ISS crew, lessons learned from years of on orbit and ground testing, new advances in technology state of the art, and requirements for future manned missions prompt consideration of the next logical step to enhance these systems to increase performance, robustness, reliability, and reduce on-orbit and logistical resource requirements. This paper discusses the current state of the art in ISS ECLSS technologies, and possible areas for enhancement/improvement. Potential utilization of the ISS as a testbed for on-orbit checkout of selected technology improvements is also addressed.

  1. Design of a Fast Neutral He Beam System for Feasibility Study of Charge-Exchange Alpha-Particle Diagnostics in a Thermonuclear Fusion Reactor

    CERN Document Server

    Shinto, Katsuhiro; Kitajima, Sumio; Kiyama, Satoru; Nishiura, Masaki; Sasao, Mamiko; Sugawara, Hiroshi; Takenaga, Mahoko; Takeuchi, Shu; Wada, Motoi


    For alpha-particle diagnostics in a thermonuclear fusion reactor, neutralization using a fast (~2 MeV) neutral He beam produced by the spontaneous electron detachment of a He- is considered most promising. However, the beam transport of produced fast neutral He has not been studied, because of difficulty for producing high-brightness He- beam. Double-charge-exchange He- sources and simple beam transport systems were developed and their results were reported in the PAC99* and other papers.** To accelerate an intense He- beam and verify the production of the fast neutral He beam, a new test stand has been designed. It consists of a multi-cusp He+

  2. Next steps in the Energy Frontier - Hadron colliders workshop at LPC@FNAL

    CERN Document Server


    With the observation of the Standard Model Higgs boson, the high energy physics community is investigating possible next steps for entering into a new era in particle physics. The aim of this workshop is to bring together physics, instrumentation/detector and accelerator experts to present, outline and discuss all aspects needed for the next steps in the energy frontier. The workshop will focus on the lessons learned with 7 and 8 TeV LHC, physics requirements and subsequent detector technologies for HL-LHC, as well as development needs for future 100 TeV proton collider. The goal is to identify synergies and common approaches where further collaboration between various initiatives could be fruitful. The discovery potential for a future 100 TeV proton collider will depend on the detector / instrumentation capabilities in order to explore the highest energy and phenomena. Many of these detection capabilities will need further studies such as muon detection at several 10s of TeV range, calorimeters capable of me...

  3. Global seismic inversion as the next standard step in the processing sequence

    Energy Technology Data Exchange (ETDEWEB)

    Maver, Kim G.; Hansen, Lars S.; Jepsen, Anne-Marie; Rasmussen, Klaus B.


    Seismic inversion of post stack seismic data has until recently been regarded as a reservoir oriented method since the standard inversion techniques rely on extensive well control and a detailed user derived input model. Most seismic inversion techniques further requires a stable wavelet. As a consequence seismic inversion is mainly utilised in mature areas focusing of specific zones only after the seismic data has been interpreted and is well understood. By using an advanced 3-D global technique, seismic inversion is presented as the next standard step in the processing sequence. The technique is robust towards noise within the seismic data, utilizes a time variant wavelet, and derives a low frequency model utilizing the stacking velocities and only limited well control. 4 figs.

  4. Analysis of quench-vent pressures for present design of ITER (International Thermonuclear Experimental Reactor) TF (toroidal field) coils

    Energy Technology Data Exchange (ETDEWEB)

    Slack, D.S.


    The International Thermonuclear Experimental Reactor (ITER) is a new tokamak design project with joint participation from Japan, the European Community, the Union of the Soviet Union, and the United States. This paper examines the effects of a quench within the toroidal field (TF) coils based on current ITER design. It is a preliminary, rough analysis. Its intent is to assist ITER designers while more accurate computer codes are being developed and to provide a check against these more rigorous solutions. Rigorous solutions to the quench problem are very complex involving three- dimensional heat transfer, extreme changes in heat capacities and copper resistivity, and varying flow dynamics within the conductors. This analysis addresses all these factors in an approximate way. The result is much less accurate than a rigorous analysis. Results here could be in error as much as 30 to 40 percent. However, it is believed that this paper can still be very useful to the coil designer. Coil pressures and temperatures vs time into a quench are presented. Rate of helium vent, energy deposition in the coil, and depletion of magnetic stored energy are also presented. Peak pressures are high (about 43 MPa). This is due to the very long vent path length (446 m), small hydraulic diameters, and high current densities associated with ITER's cable-in-conduit design. The effects of these pressures as well as the ability of the coil to be self protecting during a quench are discussed. 3 refs., 1 fig., 3 tabs.

  5. Thermonuclear land of plenty (United States)

    Gasior, P.


    Since the process of energy production in the stars has been identified as the thermonuclear fusion, this mechanism has been proclaimed as a future, extremely modern, reliable and safe for sustaining energetic needs of the humankind. However, the idea itself was rather straightforward and the first attempts to harness thermonuclear reactions have been taken yet in 40s of the twentieth century, it quickly appeared that physical and technical problems of domesticating exotic high temperature medium known as plasma are far from being trivial. Though technical developments as lasers, superconductors or advanced semiconductor electronics and computers gave significant contribution for the development of the thermonuclear fusion reactors, for a very long time their efficient performance was out of reach of technology. Years of the scientific progress brought the conclusions that for the development of the thermonuclear power plants an enormous interdisciplinary effort is needed in many fields of science covering not only plasma physics but also material research, superconductors, lasers, advanced diagnostic systems (e.g. spectroscopy, interferometry, scattering techniques, etc.) with huge amounts of data to be processed, cryogenics, measurement-control systems, automatics, robotics, nanotechnology, etc. Due to the sophistication of the problems with plasma control and plasma material interactions only such a combination of the research effort can give a positive output which can assure the energy needs of our civilization. In this paper the problems of thermonuclear technology are briefly outlined and it is shown why this domain can be a broad field for the experts dealing with electronics, optoelectronics, programming and numerical simulations, who at first glance can have nothing common with the plasma or nuclear physics.

  6. Study on the Neutrino Oscillation with a Next Generation Medium-Baseline Reactor Experiment

    Directory of Open Access Journals (Sweden)

    Chang Dong Shin


    Full Text Available For over fifty years, reactor experiments have played an important role in neutrino physics, in both discoveries and precision measurements. One of the methods to verify the existence of neutrino is the observation of neutrino oscillation phenomena. Electron antineutrinos emitted from a reactor provide the measurement of the small mixing angle θ13, providing rich programs of neutrino properties, detector development, nuclear monitoring, and application. Using reactor neutrinos, future reactor neutrino experiments, more precise measurements of θ12,  Δm122, and mass hierarchy will be explored. The precise measurement of θ13 would be crucial for measuring the CP violation parameters at accelerators. Therefore, reactor neutrino physics will assist in the complete understanding of the fundamental nature and implications of neutrino masses and mixing. In this paper, we investigated several characteristics of RENO-50, which is a future medium-baseline reactor neutrino oscillation experiment, by using the GloBES simulation package.

  7. Study on the Neutrino Oscillation with a Next Generation Medium-Baseline Reactor Experiment


    Chang Dong Shin; Kyung Kwang Joo


    For over fifty years, reactor experiments have played an important role in neutrino physics, in both discoveries and precision measurements. One of the methods to verify the existence of neutrino is the observation of neutrino oscillation phenomena. Electron antineutrinos emitted from a reactor provide the measurement of the small mixing angle θ13 , providing rich programs of neutrino properties, detector development, nuclear monitoring, and application. Using reactor neutrinos, future reacto...

  8. Next Steps in Attachment Theory


    Bell, David C.


    Thanks to the phenomenal success of attachment theory, great progress has been made in understanding child and adult relationships. The success of attachment theory opens the way to new research directions that can extend its successes even further. In particular, more work on the fundamental nature of attachment that respects recent biological research is important, as is concentrated effort on the related caregiving system.

  9. Next Steps in Attachment Theory. (United States)

    Bell, David C


    Thanks to the phenomenal success of attachment theory, great progress has been made in understanding child and adult relationships. The success of attachment theory opens the way to new research directions that can extend its successes even further. In particular, more work on the fundamental nature of attachment that respects recent biological research is important, as is concentrated effort on the related caregiving system.

  10. Recommendations on the Nature and Level of U.S. Participation in the International Thermonuclear Experimental Reactor Extension of the Experimental Reactor Extension of the Engineering Design Activities. Panel Report To Fusion Energy Sciences Advisory Committee (FESAC)

    Energy Technology Data Exchange (ETDEWEB)



    The DOE Office of Energy Research chartered through the Fusion Energy Sciences Advisory Committee (FESAC) a panel to "address the topic of U. S. participation in an ITER construction phase, assuming the ITER Parties decide to proceed with construction." (Attachment 1: DOE Charge, September 1996). Given that there is expected to be a transition period of three to five years between the conclusion of the Engineering Design Activities (EDA) and the possible construction start, the DOE Office of Energy Research expanded the charge to "include the U.S. role in an interim period between the EDA and construction." (Attachment 2: DOE Expanded Charge, May 1997). This panel has heard presentations and received input from a wide cross-section of parties with an interest in the fusion program. The panel concluded it could best fulfill its responsibility under this charge by considering the fusion energy science and technology portion of the U.S. program in its entirety. Accordingly, the panel is making some recommendations for optimum use of the transition period considering the goals of the fusion program and budget pressures.

  11. Development of real time diagnostics and feedback algorithms for JET in view of the next step

    Energy Technology Data Exchange (ETDEWEB)

    Murari, A.; Barana, O. [Consorzio RFX Associazione EURATOM ENEA per la Fusione, Corso Stati Uniti 4, Padua (Italy); Felton, R.; Zabeo, L.; Piccolo, F.; Sartori, F. [Euratom/UKAEA Fusion Assoc., Culham Science Centre, Abingdon, Oxon (United Kingdom); Joffrin, E.; Mazon, D.; Laborde, L.; Moreau, D. [Association EURATOM-CEA, CEA Cadarache, 13 - Saint-Paul-lez-Durance (France); Albanese, R. [Assoc. Euratom-ENEA-CREATE, Univ. Mediterranea RC (Italy); Arena, P.; Bruno, M. [Assoc. Euratom-ENEA-CREATE, Univ.di Catania (Italy); Ambrosino, G.; Ariola, M. [Assoc. Euratom-ENEA-CREATE, Univ. Napoli Federico Napoli (Italy); Crisanti, F. [Associazone EURATOM ENEA sulla Fusione, C.R. Frascati (Italy); Luna, E. de la; Sanchez, J. [Associacion EURATOM CIEMAT para Fusion, Madrid (Spain)


    Real time control of many plasma parameters will be an essential aspect in the development of reliable high performance operation of Next Step Tokamaks. The main prerequisites for any feedback scheme are the precise real-time determination of the quantities to be controlled, requiring top quality and highly reliable diagnostics, and the availability of robust control algorithms. A new set of real time diagnostics was recently implemented on JET to prove the feasibility of determining, with high accuracy and time resolution, the most important plasma quantities. With regard to feedback algorithms, new model-based controllers were developed to allow a more robust control of several plasma parameters. Both diagnostics and algorithms were successfully used in several experiments, ranging from H-mode plasmas to configuration with ITBs (internal thermal barriers). Since elaboration of computationally heavy measurements is often required, significant attention was devoted to non-algorithmic methods like Digital or Cellular Neural/Nonlinear Networks. The real time hardware and software adopted architectures are also described with particular attention to their relevance to ITER. (authors)

  12. On the stability of thermonuclear detonation in supernovae events (United States)

    Kriminski, S. A.; Bychkov, V. V.; Liberman, M. A.


    The stability of a plane stationary thermonuclear detonation in an exploding carbon white dwarf is investigated. It is shown that detonation is unstable in a wide range of densities of white dwarf matter from ϱ ≈ 2 × 10 7g/cm 3 to ϱ = 3 × 10 9g/cm 3. The detonation wave becomes stable at low densities ϱ ≲ 10 7g/cm 3 typical for a pre-expanded white dwarf. An important feature of the obtained detonation stability spectrum is the presence of unstable modes of zero frequency, that may result in self-quenching of the detonation at the non-linear stage of the instability. Therefore, the detonation stability analysis suggests that detonation in white dwarfs cannot propagate at sufficiently high densities: ϱ ≥ 2.1 × 10 7g/cm 3. The effect of the detonation self-quenching at high densities of the carbon-oxygen fuel may provide the physical explanation for the delayed detonation triggering in the thermonuclear supernovae.

  13. Joining of SiC[sub f]/SiC composites for thermonuclear fusion reactors

    Energy Technology Data Exchange (ETDEWEB)

    Ferraris, M. (Dipartimento di Scienza dei Materiali e Ingegneria Chimica, Politecnico di Torino, C. Duca degli Abruzzi 24, I-10129 Torino (Italy)); Badini, C. (Dipartimento di Scienza dei Materiali e Ingegneria Chimica, Politecnico di Torino, C. Duca degli Abruzzi 24, I-10129 Torino (Italy)); Montorsi, M. (Dipartimento di Scienza dei Materiali e Ingegneria Chimica, Politecnico di Torino, C. Duca degli Abruzzi 24, I-10129 Torino (Italy)); Appendino, P. (Dipartimento di Scienza dei Materiali e Ingegneria Chimica, Politecnico di Torino, C. Duca degli Abruzzi 24, I-10129 Torino (Italy)); Scholz, H.W. (Institute for Advanced Materials, CEC Joint Research Centre, I-21020 Ispra (Vatican City State, Holy See) (Italy))


    Due to their favourable radiological behaviour, SiC[sub f]/SiC composites are promising structural materials for future use in fusion reactors. A problem to cope with is the joining of the ceramic composite material (CMC) to itself for more complex structures. Maintenance concepts for a reactor made of SiC[sub f]/SiC will demand a method of joining. The joining agents should comply with the low-activation approach of the base material. With the acceptable elements Si and Mg, sandwich structures of composite/metal/composite were prepared in Ar atmosphere at temperatures just above the melting points of the metals. Another promising route is the use of joining agents of boro-silicate glasses: their composition can be tailored to obtain softening temperatures of interest for fusion applications. The glassy joint can be easily ceramised to improve thermomechanical properties. The joining interfaces were investigated by SEM-EDS, XRD and mechanical tests. ((orig.))

  14. The next step for stress research in primates: To identify relationships between glucocorticoid secretion and fitness. (United States)

    Beehner, Jacinta C; Bergman, Thore J


    Glucocorticoids are hormones that mediate the energetic demands that accompany environmental challenges. It is therefore not surprising that these metabolic hormones have come to dominate endocrine research on the health and fitness of wild populations. Yet, several problems have been identified in the vertebrate research that also apply to the non-human primate research. First, glucocorticoids should not be used as a proxy for fitness (unless a link has previously been established between glucocorticoids and fitness for a particular population). Second, stress research in behavioral ecology has been overly focused on "chronic stress" despite little evidence that chronic stress hampers fitness in wild animals. Third, research effort has been disproportionately focused on the causes of glucocorticoid variation rather than the fitness consequences. With these problems in mind, we have three objectives for this review. We describe the conceptual framework behind the "stress concept", emphasizing that high glucocorticoids do not necessarily indicate a stress response, and that a stress response does not necessarily indicate an animal is in poor health. Then, we conduct a comprehensive review of all studies on "stress" in wild primates, including any study that examined environmental factors, the stress response, and/or fitness (or proxies for fitness). Remarkably, not a single primate study establishes a connection between all three. Finally, we provide several recommendations for future research in the field of primate behavioral endocrinology, primarily the need to move beyond identifying the factors that cause glucocorticoid secretion to additionally focus on the relationship between glucocorticoids and fitness. We believe that this is an important next step for research on stress physiology in primates. Copyright © 2017 Elsevier Inc. All rights reserved.

  15. Simplest AB-Thermonuclear Space Propulsion and Electric Generator


    Bolonkin, Alexander


    The author applies, develops and researches mini-sized Micro- AB Thermonuclear Reactors for space propulsion and space power systems. These small engines directly convert the high speed charged particles produced in the thermonuclear reactor into vehicle thrust or vehicle electricity with maximum efficiency. The simplest AB-thermonuclear propulsion offered allows spaceships to reach speeds of 20,000 50,000 km/s (1/6 of light speed) for fuel ratio 0.1 and produces a huge amount of useful elect...

  16. The thermonuclear model for γ-ray bursts (United States)

    Woosley, S. E.


    The evolution of magnetized neutron stars with field strengths of ~1012 gauss that are accreting mass onto kilometer-sized polar regions at a rate of ~10-13 Msolar yr-1 is examined. Based on the results of one-dimensional calculations, one finds that stable hydrogen burning, mediated by the ``hot'' CNO-cycle, will lead to a critical helium mass in the range 1020 to 1022 g km-2. Owing to the extreme degeneracy of the electron gas providing pressure support, helium burning occurs as a violent thermonuclear runaway which may propagate either as a convective deflagration (Type I burst) or as a detonation wave (Type II burst). Complete combustion of helium into 56Ni releases from 1038 to 1040 erg km-2 and pushes hot plasma with β>~1 above the surface of the neutron star. Rapid expansion of the plasma channels a substantial fraction of the explosion energy into magnetic field stress. Spectral properties are expected to be complex with emission from both thermal and non-thermal processes. The hard γ-outburst of several seconds softens as the event proceeds and is followed by a period, typically of several minutes duration, of softer x-ray emission as the subsurface ashes of the thermonuclear explosion cool. In this model, most γ-ray bursts currently being observed are located at a distance of several hundred parsecs and should recur on a timescale of months to centuries with convective deflagrations (Type I bursts) being the more common variety. An explanation for ``Jacobson-like'' transients is also offered.

  17. Taking the Next Step: Confronting the Legacies of Slavery at Historic Sites (United States)

    Grim, Linnea; Wickens, K. Allison; Jecha, Jackie; Powell, Linda; Hawkins, Callie; Flanagan, Candra


    "Slavery is the ground zero of race relations," declared James and Lois Horton in their groundbreaking book, "Slavery and Public History." Engaging the history and legacy of slavery is a crucial step in understanding current U.S. society especially race relations. Historic sites that have connections to slavery have begun to…

  18. Adjustable Speed Drives in the Next Decade. Future Steps in Industry and Academia

    DEFF Research Database (Denmark)

    Thøgersen, Paul; Blaabjerg, Frede


    The main trends for the next decade within the multi-disciplinarian field of adjustable speed drives are discussed, and a number of topics are especially addressed in this paper. The topics include market development over the last decade, historical development in power converter volume and weight......, future drive demands, power converter architecture, interfacing to the grid, motor types, and control principles. Furthermore, some of the possibilities and trends related to decentral ?intelligence? and Internet connection are discussed....

  19. Space Drive Physics: Introduction and Next Steps (United States)

    Millis, M. G.

    Research toward the visionary goal of propellantless ``space drives'' is introduced, covering key physics issues and a listing of roughly 2-dozen approaches. The targeted advantage of a space drive is to circumvent the propellant constraints of rockets and the maneuvering limits of light sails by using the interactions between the spacecraft and its surrounding space for propulsion. At present, the scientific foundations from which to engineer a space drive have not been discovered and, objectively, might be impossible. Although no propulsion breakthroughs appear imminent, the subject has matured to where the relevant questions have been broached and are beginning to be answered. The critical make-break issues include; conservation of momentum, uncertain sources of reaction mass, and the net-external thrusting requirement. Note: space drives are not necessarily faster- than-light devices. Speed limits are a separate, unanswered issue. Relevant unsolved physics includes; the sources and mechanisms of inertial frames, coupling of gravitation and electromagnetism, and the nature of the quantum vacuum. The propulsion approaches span mostly stages 1 through 3 of the scientific method (defining the problem, collecting data, and articulating hypotheses), while some have matured to stage 4 (testing hypotheses). Nonviable approaches include `stiction drives,' `gyroscopic antigravity,' and `lifters.' No attempt is made to gauge the prospects of the remaining approaches. Instead, a list of next-step research questions is derived from the examination of these goals, unknowns, and concepts.

  20. Final repository searching in Germany - what are the next steps?; Endlagerstandortsuche in Deutschland. Wie geht's weiter?

    Energy Technology Data Exchange (ETDEWEB)

    Neles, Julia Mareike [Oeko-Institut e.V., Darmstadt (Germany). Bereich Nukleartechnik und Anlagensicherheit


    Up to now (2016) the question of final disposal of high-level radioactive wastes is still open in Germany. The Commission of radioactive waste disposal has finalized its report including recommendations for the further process. The next step will be the site selection procedure based on a ''white map''. The protest of several Federal states and communities against repository sites in their region is already developing.

  1. Improving selectivity of the Baltic cod pelagic trawl fishery: Experiments to assess the next step

    DEFF Research Database (Denmark)

    Madsen, Niels; Tschernij, Vesa; Holst, René


    or present legislation and that were developed to meet requirements of increased selectivity performance. A standard nominal 135 mm diamond mesh codend, a codend with two nominal 125 mm bottom windows, and a codend with a nominal 125 mm nominal top window were tested using the covered codend method. A Danish...... and a Swedish commercial vessel were used for the sea trials to account for potential differences between vessels. Potential differences among the three gear variants were assessed by a two-step mixed effects model. The codend catch weight was found to have a significant effect on the selectivity in some cases...

  2. High Temperature Gas-Cooled Reactors Lessons Learned Applicable to the Next Generation Nuclear Plant

    Energy Technology Data Exchange (ETDEWEB)

    J. M. Beck; L. F. Pincock


    The purpose of this report is to identify possible issues highlighted by these lessons learned that could apply to the NGNP in reducing technical risks commensurate with the current phase of design. Some of the lessons learned have been applied to the NGNP and documented in the Preconceptual Design Report. These are addressed in the background section of this document and include, for example, the decision to use TRISO fuel rather than BISO fuel used in the Peach Bottom reactor; the use of a reactor pressure vessel rather than prestressed concrete found in Fort St. Vrain; and the use of helium as a primary coolant rather than CO2. Other lessons learned, 68 in total, are documented in Sections 2 through 6 and will be applied, as appropriate, in advancing phases of design. The lessons learned are derived from both negative and positive outcomes from prior HTGR experiences. Lessons learned are grouped according to the plant, areas, systems, subsystems, and components defined in the NGNP Preconceptual Design Report, and subsequent NGNP project documents.

  3. Getting Ahead Three Steps to Take Your Career to the Next Level

    CERN Document Server

    Garfinkle, Joel A


    A leading executive coach pinpoints three vital traits necessary to advance your career In Getting Ahead, one of the top 50 executive coaches in the United States, Joel Garfinkle reveals his signature model for mastering three skills to take your career to the next level: Perception, Visibility, and Influence. The PVI-model of professional advancement will teach you to: (1) Actively promote yourself as an asset and valuable person inside the organization, (2) Increase your visibility to gain others' recognition and appreciation for your efforts and (3) Become a person of influence who makes ke

  4. NASA's Commercial Crew Program, The Next Step in U.S. Space Transportation (United States)

    Mango, Edward J.; Thomas, Rayelle E.


    The Commercial Crew Program (CCP) is leading NASA's efforts to develop the next U.S. capability for crew transportation and rescue services to and from the International Space Station (ISS) by the mid-decade timeframe. The outcome of this capability is expected to stimulate and expand the U.S. space transportation industry. NASA is relying on its decades of human space flight experience to certify U.S. crewed vehicles to the ISS and is doing so in a two phase certification approach. NASA Certification will cover all aspects of a crew transportation system, including development, test, evaluation, and verification; program management and control; flight readiness certification; launch, landing, recovery, and mission operations; sustaining engineering and maintenance/upgrades. To ensure NASA crew safety, NASA Certification will validate technical and performance requirements, verify compliance with NASA requirements, validate the crew transportation system operates in appropriate environments, and quantify residual risks.

  5. Preliminary design of a Tandem-Mirror-Next-Step facility

    Energy Technology Data Exchange (ETDEWEB)

    Damm, C.C.; Doggett, J.N.; Bulmer, R.H.


    The Tandem-Mirror-Next-Step (TMNS) facility is designed to demonstrate the engineering feasibility of a tandem-mirror reactor. The facility is based on a deuterium-tritium (D-T) burning, tandem-mirror device with a fusion power output of 245 MW. The fusion power density in the central cell is 2.1 MW/m/sup 3/, with a resultant neutron wall loading of 0.5 MW/m/sup 2/. Overall machine length is 116 m, and the effective central-cell length is 50.9 m. The magnet system includes end cells with yin-yang magnets to provide magnetohydrodynamic (MHD) stability and thermal-barrier cells to help achieve a plasma Q of 4.7 (where Q = fusion power/injected power). Neutral beams at energies up to 200 keV are used for plasma heating, fueling, and barrier pumping. Electron cyclotron resonant heating at 50 and 100 GHz is used to control the electron temperature in the barriers. Based on the resulting engineering design, the overall cost of the facility is estimated to be just under $1 billion. Unresolved physics issues include central-cell ..beta..-limits against MHD ballooning modes (the assumed reference value of ..beta.. exceeds the current theory-derived limit), and the removal of thermalized ..cap alpha..-particles from the plasma.

  6. Ignition of a Thermonuclear Detonation Wave in the Focus of Two Magnetically Insulated Transmission Lines (United States)

    Winterberg, F.


    For the ignition of a thermonuclear detonation wave assisted by a strong magnetic field, it is proposed to use two concentrically nested magnetically insulated transmission lines, the inner one transmitting a high- voltage lower-current-, and the outer one a high-current lower-voltage- electromagnetic pulse drawn from two Marx generators. The concept has the potential of large thermonuclear gains with an input energy conceivably as small as 105 J.

  7. Hepatitis B virus: Where do we stand and what is the next step for eradication? (United States)

    Komatsu, Haruki


    Hepatitis B (HB) virus (HBV) infection, which causes liver cirrhosis and hepatocellular carcinoma, is endemic worldwide. Hepatitis B vaccines became commercially available in the 1980s. The World Health Organization recommended the integration of the HB vaccine into the national immunisation programs in all countries. HBV prevention strategies are classified into three groups: (1) universal vaccination alone; (2) universal vaccination with screening of pregnant women plus HB immune globulin (HBIG) at birth; and (3) selective vaccination with screening of pregnant women plus HBIG at birth. Most low-income countries have adopted universal vaccine programs without screening of pregnant women. However, HB vaccines are not widely used in low-income countries. The Global Alliance for Vaccine and Immunization was launched in 2000, and by 2012, the global coverage of a three-dose HB vaccine had increased to 79%. The next challenges are to further increase the coverage rate, close the gap between recommendations and routine practices, approach high-risk individuals, screen and treat chronically infected individuals, and prevent breakthrough infections. To eradicate HBV infections, strenuous efforts are required to overcome socioeconomic barriers to the HB vaccine; this task is expected to take several decades to complete. PMID:25083074

  8. Next Steps: Water Technology Advances (Research) (United States)

    This project will focus on contaminants and their impact on health, adequate removal of contaminants from various water systems, and water and resource recovery within treatment systems. It will develop the next generation of technological advances to provide guidance in support ...

  9. Taking the Plunge: Next Steps in Engaged Learning: Project Kaleidoscope-Connecticut Conference of Independent Colleges Conference for Science Educators. (United States)

    Frederick, Jennifer


    College and university science educators from across Connecticut gathered at Yale's West Campus in April 2010 for a Project Kaleidoscope (PKAL) program entitled "Taking the Plunge: Next Steps in Engaged Learning." Funded by the National Science Foundation (NSF) and co-sponsored by the Connecticut Conference of Independent Colleges (CCIC) and Yale's McDougal Graduate Teaching Center, the event was the latest in a PKAL series of one-day conferences aimed at equipping science, technology, engineering, and math (STEM) instructors with effective approaches to engaging students and training future scientists.

  10. High efficient waste-to-energy in Amsterdam: getting ready for the next steps. (United States)

    Murer, Martin J; Spliethoff, Hartmut; de Waal, Chantal M W; Wilpshaar, Saskia; Berkhout, Bart; van Berlo, Marcel A J; Gohlke, Oliver; Martin, Johannes J E


    Waste-to-energy (WtE) plants are traditionally designed for clean and economical disposal of waste. Design for output on the other hand was the guideline when projecting the HRC (HoogRendement Centrale) block of Afval Energie Bedrijf Amsterdam. Since commissioning of the plant in 2007, operation has continuously improved. In December 2010, the block's running average subsidy efficiency for one year exceeded 30% for the first time. The plant can increase its efficiency even further by raising the steam temperature to 480°C. In addition, the plant throughput can be increased by 10% to reduce the total cost of ownership. In order to take these steps, good preparation is required in areas such as change in heat transfer in the boiler and the resulting higher temperature upstream of the super heaters. A solution was found in the form of combining measured data with a computational fluid dynamics (CFD) model. Suction and acoustic pyrometers are used to obtain a clear picture of the temperature distribution in the first boiler pass. With the help of the CFD model, the change in heat transfer and vertical temperature distribution was predicted. For the increased load, the temperature is increased by 100°C; this implies a higher heat transfer in the first and second boiler passes. Even though the new block was designed beyond state-of-the art in waste-to-energy technology, margins remain for pushing energy efficiency and economy even further.

  11. Focused particle beam nano-machining: the next evolution step towards simulation aided process prediction. (United States)

    Plank, Harald


    During the last decade, focused ion beam processing has been developed from traditionally used Ga(+) liquid ion sources towards higher resolution gas field ion sources (He(+) and Ne(+)). Process simulations not only improve the fundamental understanding of the relevant ion-matter interactions, but also enable a certain predictive power to accelerate advances. The historic 'gold' standard in ion-solid simulations is the SRIM/TRIM Monte Carlo package released by Ziegler, Ziegler and Biersack 2010 Nucl. Instrum. Methods B 268 1818-23. While SRIM/TRIM is very useful for a myriad of applications, it is not applicable for the understanding of the nanoscale evolution associated with ion beam nano-machining as the substrate does not evolve with the sputtering process. As a solution for this problem, a new, adapted simulation code is briefly overviewed and finally addresses these contributions. By that, experimentally observed Ne(+) beam sputter profiles can be explained from a fundamental point of view. Due to their very good agreement, these simulations contain the potential for computer aided optimization towards predictable sputter processes for different nanotechnology applications. With these benefits in mind, the discussed simulation approach represents an enormous step towards a computer based master tool for adaptable ion beam applications in the context of industrial applications.

  12. Thermonuclear fusion in the UK: towards a new abundant and durable energy source; La fusion nucleaire au Royaume-Uni: vers une nouvelle source d'energie abondante et durable

    Energy Technology Data Exchange (ETDEWEB)



    The ITER treaty (International thermonuclear experimental reactor) was signed in Paris on November 21, 2006, by the European Union, China, the USA, Japan and Russia. This treaty is devoted to the construction and exploitation of the biggest thermonuclear facility ever, capable to generate 500 MW during a reaction of 10 minutes. ITER is a priori the last experimental step before the construction of a fusion power plant for power generation at the industrial scale. The goal of ITER is to obtain a quasi-unexhaustible and less polluting energy source by the mid-21. century. The British research work has largely contributed to the development of this technology through a large number of projects that have preceded ITER but also through its present day involvement in the creation of the future reactor of Cadarache. This document presents: the UK fusion program, the projects carried out at the Culham science centre (Compass-D, Joint European Torus (JET), Small Tight Aspect Ratio Tokamak (START), Mega-Ampere Spherical Tokamak (MAST), EASY-2005 (European activation system)), the British involvement in ITER project and the transfer of technologies, and the nuclear fusion research in British universities (PPRG Imperial College London, CFSA Warwick university, Dalton nuclear institute (DNI), department of physics York university). (J.S.)

  13. Configuring the thermochemical hydrogen sulfuric acid process step for the Tandem Mirror Reactor

    Energy Technology Data Exchange (ETDEWEB)

    Galloway, T.R.


    This paper identifies the sulfuric acid step as the critical part of the thermochemical cycle in dictating the thermal demands and temperature requirements of the heat source. The General Atomic Sulfur-Iodine Cycle is coupled to a Tandem Mirror. The sulfuric acid decomposition process step is focused on specifically since this step can use the high efficiency electrical power of the direct converter together with the other thermal-produced electricity to Joule-heat a non-catalytic SO/sub 3/ decomposer to approximately 1250/sup 0/K. This approach uses concepts originally suggested by Dick Werner and Oscar Krikorian. The blanket temperature can be lowered to about 900/sup 0/K, greatly alleviating materials problems, the level of technology required, safety problems, and costs. A moderate degree of heat has been integrated to keep the cycle efficiency around 48%, but the number of heat exchangers has been limited in order to keep hydrogen production costs within reasonable bounds.

  14. Breaking the deadlock: public health policy coordination as the next step. (United States)

    Bernier, Nicole F; Burlone, Nathalie


    Recent public health crises have revealed the extent to which coordinated government activity is crucial for ensuring the efficacy of public policies aimed at protecting, maintaining and improving the health of the population. The need for coherent and effective interventions in many areas of human activity always comes up against the challenges related to the division of responsibilities, power and jurisdictions inherent in public administration. The recently initiated renewal of public health structures in Canada opens up new possibilities for public health and could foster better coordination of public health efforts. This paper shows, however, that the eventual broadening of the traditional mandate of Canadian public health to include the social (non-medical) aspects of health and the articulation of healthy public policies requires intervention at the central policy level. We offer practical observations about the need to foster better policy coordination across sectors of governments, with a view to contributing to the emergence of a comprehensive public health policy in Canada.

  15. Dolphin Therapy: The Playful Way to Work toward the Next Step (United States)

    Wermer, Maaike


    More than 400 children with a physical and/or mental challenge visit the Curacao Dolphin Therapy and Research Center (CDTC) for dolphin-assisted therapy every year. Dolphin therapy appears to be the right approach for many children. With the help of these special and very social animals, it is easier to make contact with the children. It motivates…

  16. The Urban Environmental Monitoring/100 Cities Project: Legacy of the First Phase and Next Steps (United States)

    Stefanov, William L.; Wentz, Elizabeth A.; Brazel, Anthony; Netzband, Maik; Moeller, Matthias


    The Urban Environmental Monitoring (UEM) project, now known as the 100 Cities Project, at Arizona State University (ASU) is a baseline effort to collect and analyze remotely sensed data for 100 urban centers worldwide. Our overarching goal is to use remote sensing technology to better understand the consequences of rapid urbanization through advanced biophysical measurements, classification methods, and modeling, which can then be used to inform public policy and planning. Urbanization represents one of the most significant alterations that humankind has made to the surface of the earth. In the early 20th century, there were less than 20 cities in the world with populations exceeding 1 million; today, there are more than 400. The consequences of urbanization include the transformation of land surfaces from undisturbed natural environments to land that supports different forms of human activity, including agriculture, residential, commercial, industrial, and infrastructure such as roads and other types of transportation. Each of these land transformations has impacted, to varying degrees, the local climatology, hydrology, geology, and biota that predate human settlement. It is essential that we document, to the best of our ability, the nature of land transformations and the consequences to the existing environment. The focus in the UEM project since its inception has been on rapid urbanization. Rapid urbanization is occurring in hundreds of cities worldwide as population increases and people migrate from rural communities to urban centers in search of employment and a better quality of life. The unintended consequences of rapid urbanization have the potential to cause serious harm to the environment, to human life, and to the resulting built environment because rapid development constrains and rushes decision making. Such rapid decision making can result in poor planning, ineffective policies, and decisions that harm the environment and the quality of human life

  17. Preventing Overdiagnosis and Overtreatment: Just the Next Step in the Evolution of Breast Cancer Care. (United States)

    Mukhtar, Rita A; Wong, Jasmine M; Esserman, Laura J


    The problem of overdiagnosis and overtreatment has been highlighted in breast cancer and many other cancer types, most notably prostate cancer. Addressing this problem presents an opportunity to continue the evolution of breast cancer care. Advances in technology, such as molecular subtyping, have increased the understanding of breast cancer biology and the range of associated behavior, and have provided tools that allow greater personalization of treatment. This article identifies 3 areas of breast cancer care where opportunity currently exists to refine management strategies and help decrease overtreatment and overdiagnosis: the use of adjuvant-external beam radiation in invasive breast cancer, the application of aggressive treatment for all ductal carcinoma in situ, and the authors' approach to breast cancer screening. Personalizing treatment based on patient and tumor characteristics holds promise for minimizing harms and maximizing benefits. This approach will allow continual improvement and ultimately result in providing the right treatment for each patient. Copyright © 2015 by the National Comprehensive Cancer Network.

  18. Posttranslational modifications of proteins in type 1 diabetes: the next step in finding the cure? (United States)

    Dunne, Jessica L; Overbergh, Lut; Purcell, Anthony W; Mathieu, Chantal


    The overall role of modification of β-cell antigens in type 1 diabetes has not been elucidated and was the focus of a recent workshop on posttranslational modification of proteins in type 1 diabetes. The prevailing opinion of the workshop attendees was that novel insights into the mechanism of loss of immune tolerance might be gained and that novel diagnostic and therapeutic approaches could be developed for type 1 diabetes if protein modifications were shown to play a critical role in the disease.

  19. Is 'virtual histology' the next step after the 'virtual autopsy'? Magnetic resonance microscopy in forensic medicine. (United States)

    Thali, M J; Dirnhofer, R; Becker, R; Oliver, W; Potter, K


    The study aimed to validate magnetic resonance microscopy (MRM) studies of forensic tissue specimens (skin samples with electric injury patterns) against the results from routine histology. Computed tomography and magnetic resonance imaging are fast becoming important tools in clinical and forensic pathology. This study is the first forensic application of MRM to the analysis of electric injury patterns in human skin. Three-dimensional high-resolution MRM images of fixed skin specimens provided a complete 3D view of the damaged tissues at the site of an electric injury as well as in neighboring tissues, consistent with histologic findings. The image intensity of the dermal layer in T2-weighted MRM images was reduced in the central zone due to carbonization or coagulation necrosis and increased in the intermediate zone because of dermal edema. A subjacent blood vessel with an intravascular occlusion supports the hypothesis that current traveled through the vascular system before arcing to ground. High-resolution imaging offers a noninvasive alternative to conventional histology in forensic wound analysis and can be used to perform 3D virtual histology.

  20. Taking the moral hazard out of banking: the next fundamental step in financial reform

    Directory of Open Access Journals (Sweden)

    Rainer Masera


    Full Text Available The path between financial meltdown and moral hazard in banking is, at best, narrow and impervious. During the financial crisis, public support became the standard response to save the banks in difficulty, heightening and broadening the moral hazard issue: subordinated/senior debt holders and large depositors were bailed out and equity holders were partially sheltered. In the Eurozone, the implicit promise to bail-out governments in difficulty has encouraged SIFIs and other financial operators to speculate on the yield differential between sovereigns and the ECB money market interest rates. The policy framework proposed here is two-pronged: the EFSF should evolve to permit more flexible and wide-ranging interventions, and be able to manage sovereign debt restructuring; with respect to SIFIs, very early corporate, market and supervisory responses are suggested. Intervention of supervisory authorities with mandatory (special powers would occur before the threshold of non-viability and, on a gone-concern basis, in terms of a European resolution procedure.

  1. BCNTB bioinformatics: the next evolutionary step in the bioinformatics of breast cancer tissue banking. (United States)

    Gadaleta, Emanuela; Pirrò, Stefano; Dayem Ullah, Abu Zafer; Marzec, Jacek; Chelala, Claude


    Here, we present an update of Breast Cancer Now Tissue Bank bioinformatics, a rich platform for the sharing, mining, integration and analysis of breast cancer data. Its modalities provide researchers with access to a centralised information gateway from which they can access a network of bioinformatic resources to query findings from publicly available, in-house and experimental data generated using samples supplied from the Breast Cancer Now Tissue Bank. This in silico environment aims to help researchers use breast cancer data to their full potential, irrespective of any bioinformatics barriers. For this new release, a complete overhaul of the IT and bioinformatic infrastructure underlying the portal has been conducted and a host of novel analytical modules established. We developed and adopted an automated data selection and prioritisation system, expanded the data content and included tissue and cell line data generated from The Cancer Genome Atlas and the Cancer Cell Line Encyclopedia, designed a host of novel analytical modalities and enhanced the query building process. Furthermore, the results are presented in an interactive format, providing researchers with greater control over the information on which they want to focus. Breast Cancer Now Tissue Bank bioinformatics can be accessed at © The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research.

  2. Alternative Aviation Fuels: Overview of Challenges, Opportunities, and Next Steps

    Energy Technology Data Exchange (ETDEWEB)

    None, None


    The Alternative Aviation Fuels: Overview of Challenges, Opportunities, and Next Steps report, published by the U.S. Department of Energy’s Bioenergy Technologies Office (BETO) provides an overview of the current state of alternative aviation fuels, based upon findings from recent peer-reviewed studies, scientific working groups, and BETO stakeholder input provided during the Alternative Aviation Fuel Workshop.

  3. Next step in the ongoing arms race between myxoma virus and wild rabbits in Australia is a novel disease phenotype (United States)

    Kerr, Peter J.; Cattadori, Isabella M.; Liu, June; Sim, Derek G.; Dodds, Jeff W.; Brooks, Jason W.; Kennett, Mary J.; Holmes, Edward C.


    In host–pathogen arms races, increases in host resistance prompt counteradaptation by pathogens, but the nature of that counteradaptation is seldom directly observed outside of laboratory models. The best-documented field example is the coevolution of myxoma virus (MYXV) in European rabbits. To understand how MYXV in Australia has continued to evolve in wild rabbits under intense selection for genetic resistance to myxomatosis, we compared the phenotypes of the progenitor MYXV and viral isolates from the 1950s and the 1990s in laboratory rabbits with no resistance. Strikingly, and unlike their 1950s counterparts, most virus isolates from the 1990s induced a highly lethal immune collapse syndrome similar to septic shock. Thus, the next step in this canonical case of coevolution after a species jump has been further escalation by the virus in the face of widespread host resistance. PMID:28808019

  4. Next step in the ongoing arms race between myxoma virus and wild rabbits in Australia is a novel disease phenotype. (United States)

    Kerr, Peter J; Cattadori, Isabella M; Liu, June; Sim, Derek G; Dodds, Jeff W; Brooks, Jason W; Kennett, Mary J; Holmes, Edward C; Read, Andrew F


    In host-pathogen arms races, increases in host resistance prompt counteradaptation by pathogens, but the nature of that counteradaptation is seldom directly observed outside of laboratory models. The best-documented field example is the coevolution of myxoma virus (MYXV) in European rabbits. To understand how MYXV in Australia has continued to evolve in wild rabbits under intense selection for genetic resistance to myxomatosis, we compared the phenotypes of the progenitor MYXV and viral isolates from the 1950s and the 1990s in laboratory rabbits with no resistance. Strikingly, and unlike their 1950s counterparts, most virus isolates from the 1990s induced a highly lethal immune collapse syndrome similar to septic shock. Thus, the next step in this canonical case of coevolution after a species jump has been further escalation by the virus in the face of widespread host resistance.

  5. DC performance and AC loss of cable-in-conduit conductors for International Thermonuclear Experimental Reactor

    National Research Council Canada - National Science Library

    Zhou, Wei; Fang, Xin-Yu; Fang, Jin; Liu, Bo


    ...) cable-in-conduit conductors(CICCs);however,the calculation of AC loss of ITER CICCs is a cumbersome task due to the complicated geometry of the multistage cables and the extreme operating conditions...

  6. Design and development of in-vessel viewing periscope for ITER (International Thermonuclear Experimental Reactor)

    Energy Technology Data Exchange (ETDEWEB)

    Obara, Kenjiro; Kakudate, Satoshi; Ito, Akira; Shibanuma, Kiyoshi; Tada, Eisuke [Department of Fusion Engineering Research, Naka Fusion Research Establishment, Japan Atomic Energy Research Institute, Naka , Ibaraki (Japan)


    An in-vessel viewing system is essential not only to detect and locate damage of components exposed to plasma, but also to monitor and assist in-vessel maintenance operation. In ITER, the in-vessel viewing system must be capable of operating at high temperature (200degC), under intense gamma radiation (30 kGy/h) and high vacuum or 1 bar inert gas. A periscope-type in-vessel viewing system has been chosen as a reference of the ITER in-vessel viewing system due to its wide viewing capability and durability for sever environments. According to the ITER research and development program, a full-scale radiation hard periscope with a length of 15 m has been successfully developed by the Japan Home Team. The performance tests have been shown sufficient capability at high temperature up to 250degC and radiation resistance over 100 MGy. This report describes the design and R and D results of the ITER in-vessel viewing periscope based on the development of 15-m-length radiation hard periscope. (author)

  7. Renormalization group and instantons in stochastic nonlinear dynamics, from self-organized criticality to thermonuclear reactors

    Energy Technology Data Exchange (ETDEWEB)

    Volchenkov, D. [Bielefeld Univ., Center of Excellence Cognitive Interaction Technology (CITEC) (Germany)


    Stochastic counterparts of nonlinear dynamics are studied by means of nonperturbative functional methods developed in the framework of quantum field theory (QFT). In particular, we discuss fully developed turbulence, including leading corrections on possible compressibility of fluids, transport through porous media, theory of waterspouts and tsunami waves, stochastic magnetohydrodynamics, turbulent transport in crossed fields, self-organized criticality, and dynamics of accelerated wrinkled flame fronts advancing in a wide canal. This report would be of interest to the broad auditorium of physicists and applied mathematicians, with a background in nonperturbative QFT methods or nonlinear dynamical systems, having an interest in both methodological developments and interdisciplinary applications. (author)

  8. What Are the Next Steps in Designing an Orthosis for Paraplegic Subjects?

    Directory of Open Access Journals (Sweden)

    Mohammad Taghi Karimi


    Conclusion: Although the HGO has better functional performance than other available orthoses, the subjects are more willing to use the RGO. The new design of orthoses must allow easy donning and doffing by the users, have enough stability during walking and standing, and enable the patients to change the alignment of the orthosis to suit their needs.

  9. Comprehensive Interpretive Plans: The Next Step in Visitor Centeredness and Business Success? (United States)

    Koke, Judy


    For this author, the in-depth conversation about Comprehensive Interpretive Plans (CIP) began at an AAM Task Force meeting in May of 2004. Building on that initial discussion, the author explores the reasons, costs and benefits of engaging in the CIP development process, and makes the case for the museum field to develop proficiency in this…

  10. Trends in Mobile Computing: State-of-the-Art and Next Steps

    CERN Document Server

    CERN. Geneva


    Computing is moving to the edge of the network. It is becoming increasingly personal and allowing people to enjoy and express themselves in unprecedented ways. The same development allows professionals and enterprises to increase quality and productivity through improved mobility. The seminar discusses the underlying technical and societal trends and the state-of-the-art of mobile computing. Examples of current developments include the transformation of mobile devices into servers, augmented reality in mobile devices and the opportunities offered by wireless sensor networks. The fusion of the physical and digital worlds enabled by mobile computing is driving industry and society to adopt new uses of digital technologies and causing the focus of development to shift from hardware products to new services. Bio:Since 2004 Prof. Jan Bosch is working as Vice President and Head of the Software and Application Technology Laboratory of Nokia Research Centre in Helsinki, Finland. The Software & Application Tec...

  11. From single-species advice to mixed-species management: taking the next step

    DEFF Research Database (Denmark)

    Vinther, Morten; Reeves, S.A.; Patterson, K.R.


    Fishery management advice has traditionally been given on a stock-by-stock basis. Recent problems in implementing this advice, particularly for the demersal fisheries of the North Sea, have highlighted the limitations of the approach. In the long term, it would be desirable to give advice...... a recent approach used to address these problems. The approach takes the single-species advice for each species in the fishery as a starting point, then attempts to resolve it into consistent catch or effort advice using fleet-disaggregated catch forecasts in combination with explicitly stated management...... priorities for each stock. Results are presented for the groundfish fisheries of the North Sea, and these show that the development of such approaches will also require development of the ways in which catch data are collected and compiled. (C) 2004 International Council for the Exploration of the Sea...

  12. A truly international lunar base as the next logical step for human spaceflight (United States)

    Bonneville, Richard

    Recent fora (e.g. the ISECG’s Global Exploration Roadmap) have highlighted a human mission to Mars as the long term goal for space exploration, with intermediate stages such as missions to the Moon and/or to asteroids. But actually a human mission to Mars will not be feasible before several decades, whereas in the meantime robotic missions will be able to provide an enormous amount of information on the history and the environment of the red planet, at a rather moderate cost. And if we consider missions to asteroids, introducing a human in the loop will require a considerably higher complexity and cost than using robots, with no significant additional benefit. The only sensible and feasible objective of a near-term human spaceflight program would be the edification of a lunar base, under the condition that this base is built as a true international venture. Science will not be the main driver; it has to be acknowledged from the beginning that the true main goal will be peace and a nucleus of international cooperation between the big countries. The ISS in the 1990’s had illustrated a calmed relation between the USA, together with Europe, Canada and Japan, and Russia. A lunar base should be the symbol of a similar calmed relation between the same partners and China. For the benefit of all humankind this extra continent, the Moon, will be used only for peaceful purposes, like Antarctica today, and will not become the theatre or the stake of conflicts. The financial cost of that venture will be high, but not that high if it is compared with the cost of recent wars; so let us go to the Moon, OK, but let us get there together.

  13. 75 FR 29359 - Draft Environmental Impact Statement for the Tamiami Trail Modifications: Next Steps Project... (United States)


    ... of a Draft Environmental Impact Statement (DEIS) for the Tamiami Trail (U.S. Highway 41.... Army Corps of Engineers (USACE) to construct modifications to U.S. Highway 41 (Tamiami Trail) that were... within the Park and the ecological connectivity between the Park and the Water Conservation Areas'' (2009...

  14. XML at the ADC: Steps to a Next Generation Data Repository (United States)

    Shaya, E.; Gass, J.; Blackwell, J.; Thomas, B.; Holmes, B.; Cheung, C. Y.

    The staff of the Astronomical Data Center at GSFC (ADC, is involved in a research project to define the XML format for the metadata of an astronomical repository and for large data tables. In the process, an XML tool box is being developed for importation, enhancement, and distribution of published data and their metadata documents. There is now a working draft Document Type Definition (DTD, which specifies the required elements of content and their attributes. The documentation for each data set will be viewable in several different styles via eXtensible Stylesheet Language Transformations (XSLT, ( scripts. The ADC is actively creating designs for the flow of data through automated pipelines from authors and journal presses into an XML archive, as well as data retrieval through the web via the XML Query Language.

  15. The Next Step: A Study on Resiliency in Command and Control (United States)


    53 1 Introduction Success is never final. John Wooden UCLA Basketball Head Coach, 10 Time NCAA Champion The historic success of...strength of personality and political skills more than “a reliable, resilient process” to institutionalize the role of the JFACC.47 The Air Force

  16. Popular Religiosity in Indonesia Today: The Next Step after ‘Islam Kultural’?


    Noor, Farish A.


    The phenomenon of popular Islam is seen everywhere in the Muslim world today, and expresses itself via a host of means ranging from fashion to architecture as well as new cultural norms that are deemed Islamic. In the case of Indonesia, the expansive growth of the ‘halal market’--pioneered by Islamic fashion and cosmetics-- has been a powerful variable factor, accounting for the emergence of a new Indonesian Muslim middle-class that has aspirations for upward social mobility as well as social...

  17. Advancing the conversation: next steps for lesbian, gay, bisexual, trans, and queer (LGBTQ) health sciences librarianship. (United States)

    Hawkins, Blake W; Morris, Martin; Nguyen, Tony; Siegel, John; Vardell, Emily


    In recent years, librarians in various sectors have been moving forward a conversation on the distinct information needs and information-seeking behavior of our lesbian, gay, bisexual, trans, and queer (LGBTQ) patrons and how well the profession recognizes and meets those needs. Health sciences librarianship has been slower than other areas of the profession in creating an evidence base covering the needs of its LGBTQ patrons, with, until recently, only very limited literature on this subject. LGBTQ health sciences librarianship is now starting to attract new interest, with librarians working together to bring this emerging specialization to the attention of the broader professional community. In this paper, the authors report on a dedicated panel discussion that took place at the 2016 joint annual meeting of the Medical Library Association and Canadian Health Libraries Association/Association des bibliothèques de la santé du Canada in Toronto, Ontario, Canada; discuss subsequent reflections; and highlight the emerging role for health sciences librarians in providing culturally competent services to the LGBTQ population. Recommendations are also provided for establishing a tool kit for LGBTQ health sciences librarianship from which librarians can draw. We conclude by highlighting the importance of critically reflective practice in health sciences librarianship in the context of LGBTQ health information.

  18. Advancing the conversation: next steps for lesbian, gay, bisexual, trans, and queer (LGBTQ) health sciences librarianship (United States)

    Hawkins, Blake W.; Morris, Martin; Nguyen, Tony; Siegel, John; Vardell, Emily


    In recent years, librarians in various sectors have been moving forward a conversation on the distinct information needs and information-seeking behavior of our lesbian, gay, bisexual, trans, and queer (LGBTQ) patrons and how well the profession recognizes and meets those needs. Health sciences librarianship has been slower than other areas of the profession in creating an evidence base covering the needs of its LGBTQ patrons, with, until recently, only very limited literature on this subject. LGBTQ health sciences librarianship is now starting to attract new interest, with librarians working together to bring this emerging specialization to the attention of the broader professional community. In this paper, the authors report on a dedicated panel discussion that took place at the 2016 joint annual meeting of the Medical Library Association and Canadian Health Libraries Association/Association des bibliothèques de la santé du Canada in Toronto, Ontario, Canada; discuss subsequent reflections; and highlight the emerging role for health sciences librarians in providing culturally competent services to the LGBTQ population. Recommendations are also provided for establishing a tool kit for LGBTQ health sciences librarianship from which librarians can draw. We conclude by highlighting the importance of critically reflective practice in health sciences librarianship in the context of LGBTQ health information. PMID:28983195

  19. Patient-centered hand hygiene: the next step in infection prevention. (United States)

    Landers, Timothy; Abusalem, Said; Coty, Mary-Beth; Bingham, James


    Hand hygiene has been recognized as the most important means of preventing the transmission of infection, and great emphasis has been placed on ways to improve hand hygiene compliance by health care workers (HCWs). Despite increasing evidence that patients' flora and the hospital environment are the primary source of many infections, little effort has been directed toward involving patients in their own hand hygiene. Most previous work involving patients has included patients as monitors or auditors of hand hygiene practices by their HCWs. This article reviews the evidence on the benefits of including patients more directly in hand hygiene initiatives, and uses the framework of patient-centered safety initiatives to provide recommendations for the timing and implementation of patient hand hygiene protocols. It also addresses key areas for further research, practice guideline development, and implications for training of HCWs. Copyright © 2012 Association for Professionals in Infection Control and Epidemiology, Inc. Published by Mosby, Inc. All rights reserved.

  20. Automated experimentation in Walden 3.0: The next step in profiling, predicting, control and surveillance

    National Research Council Canada - National Science Library

    Martijn van Otterlo


    .... Instead of bringing forward Orwell's 1984 dystopia in the privacy domain as is typically done, I sketch how current developments might be better studied in the context of Skinner's utopian novel Walden Two...

  1. Elusive Critical Elements of Transformative Risk Assessment Practice and Interpretation: Is Alternatives Analysis the Next Step? (United States)

    Francis, Royce A


    This article argues that "game-changing" approaches to risk analysis must focus on "democratizing" risk analysis in the same way that information technologies have democratized access to, and production of, knowledge. This argument is motivated by the author's reading of Goble and Bier's analysis, "Risk Assessment Can Be a Game-Changing Information Technology-But Too Often It Isn't" (Risk Analysis, 2013; 33: 1942-1951), in which living risk assessments are shown to be "game changing" in probabilistic risk analysis. In this author's opinion, Goble and Bier's article focuses on living risk assessment's potential for transforming risk analysis from the perspective of risk professionals-yet, the game-changing nature of information technologies has typically achieved a much broader reach. Specifically, information technologies change who has access to, and who can produce, information. From this perspective, the author argues that risk assessment is not a game-changing technology in the same way as the printing press or the Internet because transformative information technologies reduce the cost of production of, and access to, privileged knowledge bases. The author argues that risk analysis does not reduce these costs. The author applies Goble and Bier's metaphor to the chemical risk analysis context, and in doing so proposes key features that transformative risk analysis technology should possess. The author also discusses the challenges and opportunities facing risk analysis in this context. These key features include: clarity in information structure and problem representation, economical information dissemination, increased transparency to nonspecialists, democratized manufacture and transmission of knowledge, and democratic ownership, control, and interpretation of knowledge. The chemical safety decision-making context illustrates the impact of changing the way information is produced and accessed in the risk context. Ultimately, the author concludes that although

  2. Now for the Hard Stuff: Next Steps in ECB Research and Practice (United States)

    Preskill, Hallie


    Though several excellent literature reviews and research syntheses have been conducted, and thoughtful frameworks and models have been proposed, I believe it is time for the evaluation field to tackle the "hard stuff" of evaluation capacity building (ECB). This entails engaging staff in ECB activities, building the evaluation capacity of…

  3. Thermally Self-Healing Polymeric Materials : The Next Step to Recycling Thermoset Polymers?

    NARCIS (Netherlands)

    Zhang, Youchun; Broekhuis, Antonius A.; Picchioni, Francesco


    We developed thermally self-healing polymeric materials on the basis of furan-functionalized, alternating thermosetting polyketones (PK-furan) and bis-maleimide by using the Diels-Alder (DA) and Retro-Diels-Alder (RDA) reaction sequence. PK-furan can be easily obtained under mild conditions by the

  4. Vaccination strategies against highly pathogenic arenaviruses: the next steps toward clinical trials.

    Directory of Open Access Journals (Sweden)

    Stephan Olschläger

    Full Text Available Vaccination is one of the most valuable weapons against infectious diseases and has led to a significant reduction in mortality and morbidity. However, for most viral hemorrhagic fevers caused by arenaviruses, no prophylactic vaccine is available. This is particularly problematic as these diseases are notoriously difficult to diagnose and treat. Lassa fever is globally the most important of the fevers caused by arenaviruses, potentially affecting millions of people living in endemic areas, particularly in Nigeria. Annually, an estimated 300,000 humans are infected and several thousands succumb to the disease. The successful development of the vaccine "Candid#1" against Junin virus, the causative agent of Argentine hemorrhagic fever, proved that an effective arenavirus vaccine can be developed. Although several promising studies toward the development of a Lassa fever vaccine have been published, no vaccine candidate has been tested in human volunteers or patients. This review summarizes the immunology and other aspects of existing experimental arenavirus vaccine studies, discusses the reasons for the lack of a vaccine, and proposes a plan for overcoming the final hurdles toward clinical trials.

  5. Taking the Next Step: From ’Unmanned’ to True Autonomy (United States)


    QH-60C, with the ultimate goal of putting three DASH units on all its 240 FRAM -I and FRAM -II destroyers. In January 1965 the Navy began to use the...are currently not pursuing” (Chief of Naval Operations Strategic Studies Group, Overview , accessed at: <

  6. The sphere project: next steps in moving toward a rights-based approach to humanitarian assistance. (United States)

    Ouyang, Helen; Vanrooyen, Michael; Gruskin, Sofia


    Since the Sphere Project was launched in 1997, it has sought to integrate principles of human rights norms with adherence to technical standards. While the Sphere Handbook has evolved as both a field tool and a resource for articulating human rights, it does not fully offer a rights-based approach to humanitarian assistance. In the handbook's current edition, its Humanitarian Charter asserts and affirms human rights principles, but the technical Minimum Standards Section that follows has yet to truly embody a rights-based approach; that is, it does not clarify how to operationalize human rights in the field, particularly with respect to the health sector. Using human rights documents, the Sphere documents, and existing, published literature in the field of humanitarian practice and human rights, this article provides critical commentary and suggests how strengthening the link between rights and standards, as well as rhetoric and action, can advance the Sphere Project beyond its current applicability as a handbook of technical standards in the field to operationalizing an effective rights-based approach to humanitarian aid.

  7. Mobile phones: the next step towards healthcare delivery in rural India? (United States)

    DeSouza, Sherwin I; Rashmi, M R; Vasanthi, Agalya P; Joseph, Suchitha Maria; Rodrigues, Rashmi


    Given the ubiquity of mobile phones, their use to support healthcare in the Indian context is inevitable. It is however necessary to assess end-user perceptions regarding mobile health interventions especially in the rural Indian context prior to its use in healthcare. This would contextualize the use of mobile phone communication for health to 70% of the country's population that resides in rural India. To explore the acceptability of delivering healthcare interventions through mobile phones among users in a village in rural Bangalore. This was an exploratory study of 488 mobile phone users, residing in a village, near Bangalore city, Karnataka, South India. A pretested, translated, interviewer-administered questionnaire was used to obtain data on mobile phone usage patterns and acceptability of the mobile phone, as a tool for health-related communication. The data is described using basic statistical measures. The primary use of mobile phones was to make or receive phone calls (100%). Text messaging (SMS) was used by only 70 (14%) of the respondents. Most of the respondents, 484 (99%), were willing to receive health-related information on their mobile phones and did not consider receiving such information, an intrusion into their personal life. While receiving reminders for drug adherence was acceptable to most 479 (98%) of our respondents, 424 (89%) preferred voice calls alone to other forms of communication. Nearly all were willing to use their mobile phones to communicate with health personnel in emergencies and 367 (75%) were willing to consult a doctor via the phone in an acute illness. Factors such as sex, English literacy, employment status, and presence of chronic disease affected preferences regarding mode and content of communication. The mobile phone, as a tool for receiving health information and supporting healthcare through mHealth interventions was acceptable in the rural Indian context.

  8. Mobile phones: the next step towards healthcare delivery in rural India?

    Directory of Open Access Journals (Sweden)

    Sherwin I DeSouza

    Full Text Available BACKGROUND: Given the ubiquity of mobile phones, their use to support healthcare in the Indian context is inevitable. It is however necessary to assess end-user perceptions regarding mobile health interventions especially in the rural Indian context prior to its use in healthcare. This would contextualize the use of mobile phone communication for health to 70% of the country's population that resides in rural India. OBJECTIVES: To explore the acceptability of delivering healthcare interventions through mobile phones among users in a village in rural Bangalore. METHODS: This was an exploratory study of 488 mobile phone users, residing in a village, near Bangalore city, Karnataka, South India. A pretested, translated, interviewer-administered questionnaire was used to obtain data on mobile phone usage patterns and acceptability of the mobile phone, as a tool for health-related communication. The data is described using basic statistical measures. RESULTS: The primary use of mobile phones was to make or receive phone calls (100%. Text messaging (SMS was used by only 70 (14% of the respondents. Most of the respondents, 484 (99%, were willing to receive health-related information on their mobile phones and did not consider receiving such information, an intrusion into their personal life. While receiving reminders for drug adherence was acceptable to most 479 (98% of our respondents, 424 (89% preferred voice calls alone to other forms of communication. Nearly all were willing to use their mobile phones to communicate with health personnel in emergencies and 367 (75% were willing to consult a doctor via the phone in an acute illness. Factors such as sex, English literacy, employment status, and presence of chronic disease affected preferences regarding mode and content of communication. CONCLUSION: The mobile phone, as a tool for receiving health information and supporting healthcare through mHealth interventions was acceptable in the rural Indian

  9. Concurrent Engineering Working Group White Paper Distributed Collaborative Design: The Next Step in Aerospace Concurrent Engineering (United States)

    Hihn, Jairus; Chattopadhyay, Debarati; Karpati, Gabriel; McGuire, Melissa; Panek, John; Warfield, Keith; Borden, Chester


    As aerospace missions grow larger and more technically complex in the face of ever tighter budgets, it will become increasingly important to use concurrent engineering methods in the development of early conceptual designs because of their ability to facilitate rapid assessments and trades of performance, cost and schedule. To successfully accomplish these complex missions with limited funding, it is essential to effectively leverage the strengths of individuals and teams across government, industry, academia, and international agencies by increased cooperation between organizations. As a result, the existing concurrent engineering teams will need to increasingly engage in distributed collaborative concurrent design. The purpose of this white paper is to identify a near-term vision for the future of distributed collaborative concurrent engineering design for aerospace missions as well as discuss the challenges to achieving that vision. The white paper also documents the advantages of creating a working group to investigate how to engage the expertise of different teams in joint design sessions while enabling organizations to maintain their organizations competitive advantage.

  10. The next step in coastal numerical models: spectral/hp element methods?

    DEFF Research Database (Denmark)

    Eskilsson, Claes; Engsig-Karup, Allan Peter; Sherwin, Spencer J.


    In this paper we outline the application of spectral/hp element methods for modelling nonlinear and dispersive waves. We present one- and two-dimensional test cases for the shallow water equations and Boussinesqtype equations – including highly dispersive Boussinesq-type equations.......In this paper we outline the application of spectral/hp element methods for modelling nonlinear and dispersive waves. We present one- and two-dimensional test cases for the shallow water equations and Boussinesqtype equations – including highly dispersive Boussinesq-type equations....

  11. A New Graduate-Level Seminar to Prepare Students for the Next Step in Their Careers (United States)

    Fleming, Kelly L.; Matthaei, James; Pfaendtner, Jim


    Many new Ph.D.s are not prepared for a competitive interview process in seeking a first job. The University of Washington (UW) designed the Distinguished Young Scholars Seminar (DYSS) to rectify this problem with three goals: simulate a visit associated with many interviews and a one-hour seminar; make UW graduate students aware of where they fit…

  12. Using Comparison of Multiple Strategies in the Mathematics Classroom: Lessons Learned and Next Steps (United States)

    Durkin, Kelley; Star, Jon R.; Rittle-Johnson, Bethany


    Comparison is a fundamental cognitive process that can support learning in a variety of domains, including mathematics. The current paper aims to summarize empirical findings that support recommendations on using comparison of multiple strategies in mathematics classrooms. We report the results of our classroom-based research on using comparison…

  13. Taking the Next Step: Connecting Teacher Education, Research on Teaching, and Programme Assessment (United States)

    Metzler, Michael W.; Blankenship, Bonnie Tjeerdsma


    We cite four disconnections among teacher education programmes, research on teaching, and programme assessment that contribute to a paucity of systematically collected evidence and the inability of teacher educators to fully address the "outcomes question" [Cochran-Smith, M. (2003). Assessing assessment in teacher education.…

  14. The Next Step to Creating a More Efficient Form of Paperless Contracting (United States)


    direction. At Oracle , they “Try to look at needs out in the future…skating to where the puck will be.” Customer Relationship Management ( CRM ...23 B. SAP..................................................................................................................23 C. ORACLE ...Registration CECOM Communications - Electronics Command CRM Customer Relationship Management CS Customer Service DAASC Defense Automatic

  15. The next step toward GMP-grade production of engineered immune cells

    NARCIS (Netherlands)

    Kierkels, Guido J J; Straetemans, Trudy; de Witte, Moniek A; Kuball, Jürgen|info:eu-repo/dai/nl/314079645

    Removing less potent T cell subsets as well as poorly- or non-engineered cells can optimize effectiveness of engineered T cell therapy against cancer. We have recently described a novel, GMP-ready method for the purification of engineered immune cells that might further boost the clinical success of

  16. The next step in real time data processing for large scale physics experiments

    CERN Document Server

    Paramesvaran, Sudarshan


    Run 2 of the LHC represents one of the most challenging scientific environments for real time data analysis and processing. The steady increase in instantaneous luminosity will result in the CMS detector producing around 150 TB/s of data, only a small fraction of which is useful for interesting Physics studies. During 2015 the CMS collaboration will be completing a total upgrade of its Level 1 Trigger to deal with these conditions. In this talk a description of the major components of this complex system will be described. This will include a discussion of custom-designed electronic processing boards, built to the uTCA specification with AMC cards based on Xilinx 7 FPGAs and a network of high-speed optical links. In addition, novel algorithms will be described which deliver excellent performance in FPGAs and are combined with highly stable software frameworks to ensure a minimal risk of downtime. This upgrade is planned to take data from 2016. However a system of parallel running has been developed that will ...

  17. The Mussel Watch California pilot study on contaminants of emerging concern (CECs): synthesis and next steps (United States)

    Maruya, Keith A.; Dodder, Nathan G.; Weisberg, Stephen B.; Gregorio, Dominic; Bishop, Jonathan S.; Klosterhaus, Susan; Alvarez, David A.; Furlong, Edward T.; Bricker, Suzanne B.; Kimbrough, Kimani L.; Lauenstein, Gunnar G.


    A multiagency pilot study on mussels (Mytilus spp.) collected at 68 stations in California revealed that 98% of targeted contaminants of emerging concern (CECs) were infrequently detectable at concentrations ⩽1 ng/g. Selected chemicals found in commercial and consumer products were more frequently detected at mean concentrations up to 470 ng/g dry wt. The number of CECs detected and their concentrations were greatest for stations categorized as urban or influenced by storm water discharge. Exposure to a broader suite of CECs was also characterized by passive sampling devices (PSDs), with estimated water concentrations of hydrophobic compounds correlated with Mytilus concentrations. The results underscore the need for focused CEC monitoring in coastal ecosystems and suggest that PSDs are complementary to bivalves in assessing water quality. Moreover, the partnership established among participating agencies led to increased spatial coverage, an expanded list of analytes and a more efficient use of available resources.

  18. Collaborative learning: A next step in the training of peer support providers. (United States)

    Cronise, Rita


    This column explores how peer support provider training is enhanced through collaborative learning. Collaborative learning is an approach that draws upon the "real life" experiences of individual learners and encompasses opportunities to explore varying perspectives and collectively construct solutions that enrich the practice of all participants. This description draws upon published articles and examples of collaborative learning in training and communities of practice of peer support providers. Similar to person-centered practices that enhance the recovery experience of individuals receiving services, collaborative learning enhances the experience of peer support providers as they explore relevant "real world" issues, offer unique contributions, and work together toward improving practice. Three examples of collaborative learning approaches are provided that have resulted in successful collaborative learning opportunities for peer support providers. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

  19. Turning tumour cells into antigen presenting cells: The next step to improve cancer immunotherapy? (United States)

    de Charette, Marie; Marabelle, Aurélien; Houot, Roch


    Downregulation/loss of the antigen presentation is a major immune escape mechanism in cancer. It allows tumour cells to become 'invisible' and avoid immune attack by antitumour T cells. In tumour harbouring properties of professional antigen presenting cells (i.e. tumour B cells in lymphoma), downregulation/loss of the antigen presentation may also prevent direct priming of naïve T cells by tumour cells. Here, we review treatments that may induce/restore antigen presentation by the tumour cells. These treatments may increase the generation of antitumour T cells and/or their capacity to recognise and eliminate tumour cells. By forcing tumour cells to present their antigens, these treatments may sensitise patients to T cell-based immunotherapies, including checkpoint inhibitors. Copyright © 2016 Elsevier Ltd. All rights reserved.

  20. Moving Toward Quantifying Reliability - The Next Step in a Rapidly Maturing PV Industry: Preprint

    Energy Technology Data Exchange (ETDEWEB)

    Kurtz, Sarah; Sample, Tony; Wohlgemuth, John; Zhou, Wei; Bosco, Nick; Althaus, Joerg; Phillips, Nancy; Deceglie, Michael; Flueckiger, Chris; Hacke, Peter; Miller, David; Kempe, Michael; Yamamichi, Masaaki; Kondo, Michio


    Some may say that PV modules are moving toward being a simple commodity, but most major PV customers ask: 'How can I minimize chances of a module recall?' Or, 'How can I quantify the added value of a 'premium' module?' Or, 'How can I assess the value of an old PV system that I'm thinking of purchasing?' These are all questions that PVQAT (the International PV Quality Assurance Task Force) and partner organizations are working to answer. Defining standard methods for ensuring minimal acceptable quality of PV modules, differentiating modules that provide added value in the toughest of environments, and creating a process (e.g. through IECRE [1]) that can follow a PV system from design through installation and operation are tough tasks, but having standard approaches for these will increase confidence, reduce costs, and be a critical foundation of a mature PV industry. This paper summarizes current needs for new tests, some challenges for defining those tests, and some of the key efforts toward development of international standards, emphasizing that meaningful quantification of reliability (as in defining a service life prediction) must be done in the context of a specific product with design parameters defined through a quality management system.

  1. Puzzling thermonuclear burst behaviour from the transient low-mass X-ray binary IGR J17473-2721

    DEFF Research Database (Denmark)

    Chenevez, Jérôme; Altamirano, Diego; Galloway, Duncan


    We investigate the thermonuclear bursting behaviour of IGR J17473−2721, an X-ray transient that in 2008 underwent a 6-month long outburst, starting (unusually) with an X-ray burst. We detected a total of 57 thermonuclear bursts throughout the outburst with AGILE, Swift, Rossi X-ray Timing Explore...

  2. Endoscopic non-technical skills team training: The next step in quality assurance of endoscopy training (United States)

    Matharoo, Manmeet; Haycock, Adam; Sevdalis, Nick; Thomas-Gibson, Siwan


    AIM: To investigate whether novel, non-technical skills training for Bowel Cancer Screening (BCS) endoscopy teams enhanced patient safety knowledge and attitudes. METHODS: A novel endoscopy team training intervention for BCS teams was developed and evaluated as a pre-post intervention study. Four multi-disciplinary BCS teams constituting BCS endoscopist(s), specialist screening practitioners, endoscopy nurses and administrative staff (A) from English BCS training centres participated. No patients were involved in this study. Expert multidisciplinary faculty delivered a single day’s training utilising real clinical examples. Pre and post-course evaluation comprised participants’ patient safety awareness, attitudes, and knowledge. Global course evaluations were also collected. RESULTS: Twenty-three participants attended and their patient safety knowledge improved significantly from 43%-55% (P ≤ 0.001) following the training intervention. 12/41 (29%) of the safety attitudes items significantly improved in the areas of perceived patient safety knowledge and awareness. The remaining safety attitude items: perceived influence on patient safety, attitudes towards error management, error management actions and personal views following an error were unchanged following training. Both qualitative and quantitative global course evaluations were positive: 21/23 (91%) participants strongly agreed/agreed that they were satisfied with the course. Qualitative evaluation included mandating such training for endoscopy teams outside BCS and incorporating team training within wider endoscopy training. Limitations of the study include no measure of increased patient safety in clinical practice following training. CONCLUSION: A novel comprehensive training package addressing patient safety, non-technical skills and adverse event analysis was successful in improving multi-disciplinary teams’ knowledge and safety attitudes. PMID:25516665

  3. Regionalization of surgical services in central Florida: the next step in acute care surgery. (United States)

    Block, Ernest F J; Rudloff, Beth; Noon, Charles; Behn, Bruce


    There is a national loss of access to surgeons for emergencies. Contributing factors include reduced numbers of practicing general surgeons, superspecialization, reimbursement issues, emphasis on work and life balance, and medical liability. Regionalizing acute care surgery (ACS), as exists for trauma care, represents a potential solution. The purpose of this study is to assess the financial and resources impact of transferring all nontrauma ACS cases from a community hospital (CH) to a trauma center (TC). We performed a case mix and financial analysis of patient records with ACS for a rural CH located near an urban Level I TC. ACS patients were analyzed for diagnosis, insurance status, procedures, and length of stay. We estimated physician reimbursement based on evaluation and management codes and procedural CPT codes. Hospital revenues were based on regional diagnosis-related group rates. All third-party remuneration was set at published Medicare rates; self-pay was set at nil. Nine hundred ninety patients were treated in the CH emergency department with 188 potential surgical diseases. ACS was necessary in 62 cases; 25.4% were uninsured. Extrapolated to 12 months, 248 patients would generate new TC physician revenue of >$155,000 and hospital profits of >$1.5 million. CH savings for call pay and other variable costs are >$100,000. TC operating room volume would only increase by 1%. Regionalization of ACS to TCs is a viable option from a business perspective. Access to care is preserved during an approaching crisis in emergency general surgical coverage. The referring hospital is relieved of an unfavorable payer mix and surgeon call problems. The TC receives a new revenue stream with limited impact on resources by absorbing these patients under its fixed costs, saving the CH variable costs.

  4. We Must Take the Next Steps Towards Safe, Routine Space Travel (United States)

    Lyles, G. M.


    This paper presents, in viewgraph form, six in a half generations of airplanes in a century. Some of the topics include: 1) Enterprise goals; 2) Generations of Reusable Launch Vehicles; 3) Space Transportation Across NASA; 4) Three Tiered Implementation Approach for Future Space Transportation Technology; 5) Develop a Comprehensive, Agency Level Space Transportation Plan That Will Enable NASA's Strategic Plan; 6) Timeline for Addressing NASA's Needs; 7) Significant 2nd Generation Technology Drivers; 8) Example Large Scale Ground Demonstrations; and 9) Example Pathfinder Demonstrations. The paper also includes various aircraft designs and propulsion system technology.

  5. A Risk Management Process for Consumers: The Next Step in Information Security

    NARCIS (Netherlands)

    van Cleeff, A.


    Simply by using information technology, consumers expose themselves to considerable security risks. Because no technical or legal solutions are readily available, and awareness programs have limited impact, the only remedy is to develop a risk management process for consumers. Consumers need to

  6. Next steps in using accessory minerals to date the evolution of silicic magmas (United States)

    Vazquez, J. A.


    Over the past decade, 238U-230Th-206Pb isotopic dating of accessory minerals using the high spatial resolution and sensitivity of ion microprobe analysis has provided new insights into the longevity and thermochemical evolution of silicic magmas, but has also created new questions about the generation, differentiation, and construction of silicic magma chambers. An important conclusion from in situ dating is that accessory minerals such as zircon and allanite in silicic magmas may be 10's to 100's of thousands of years older than their age of eruption. Whether these relatively "old" crystals are derived from long-lived crystal-rich magma reservoirs or inherited due to remelting of frozen intrusions remains a difficult question to answer because long-lived centers of magmatism are characteristically dynamic and are open systems. Nevertheless, not all rhyolites from loci of repeated silicic magmatism carry a dominant "cargo" of antecrystic zircon (or other accessory minerals). Crystal-poor high-silica rhyolites from Coso volcanic field, eastern California, contain a bimodal population of young zircon that yield 238U-230Th ages concordant with their respective late Pleistocene 40Ar/39Ar eruption ages, and a population of Mesozoic zircon that are obvious xenocrysts derived from wallrocks. Rhyolites erupted from La Primavera caldera, Mexico, contain zircon and chevkinite that yield 238U-230Th ages that are within 10's of k.y. of their corresponding eruption ages between ca. 125-85 ka. Antecrysts from intrusions related to older episodes of rhyolitic magmatism appear absent or exceedingly rare. The relatively short timescales between crystallization and eruption suggest that these rhyolites, unlike otherwise similar rhyolites from other systems, were tapped shortly after highly effective differentiation and/or reheating. It is apparent that zircon ages alone are insufficient for resolving the thermochemical and differentiation histories of silicic magmas, and need to be

  7. Indicator disease-guided testing for HIV--the next step for Europe?

    DEFF Research Database (Denmark)

    Gazzard, B; Clumeck, N; d'Arminio Monforte, A


    with sexually transmitted diseases should be offered an HIV test, as should patients with certain types of cancers and laboratory abnormalities. Governments should consider adopting opt-out testing for pregnant women. These recommendations should be considered for implementation by all types of health......HIV should preferably be diagnosed in its earlier stages. To optimize the chances of doing so, HIV testing in patients presenting with one of several indicator diseases and conditions is recommended. Patients presenting with tuberculosis and other AIDS-defining conditions should be tested. Patients...

  8. Multidisciplinary Analysis and Optimization Generation 1 and Next Steps (United States)

    Naiman, Cynthia Gutierrez


    The Multidisciplinary Analysis & Optimization Working Group (MDAO WG) of the Systems Analysis Design & Optimization (SAD&O) discipline in the Fundamental Aeronautics Program s Subsonic Fixed Wing (SFW) project completed three major milestones during Fiscal Year (FY)08: "Requirements Definition" Milestone (1/31/08); "GEN 1 Integrated Multi-disciplinary Toolset" (Annual Performance Goal) (6/30/08); and "Define Architecture & Interfaces for Next Generation Open Source MDAO Framework" Milestone (9/30/08). Details of all three milestones are explained including documentation available, potential partner collaborations, and next steps in FY09.

  9. Thermonuclear Processes as a Principal Source of the Earth's Internal Energy (United States)

    Terez, E. I.; Terez, I. E.


    A cosmological model of the formation of the Solar System is presented. It is shown that the main source of the Earth's energy is delivered from the thermonuclear processes in the inner Earth's core consisting of metallic hydrides. Several theoretical studies showed that under low temperature (

  10. Development of a draft of human factors safety review procedures for the Korean next generation reactor

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Jung Woon; Moon, B. S.; Park, J. C.; Lee, Y. H.; Oh, I. S.; Lee, H. C. [Korea Atomic Energy Research Institute, Taejeon (Korea)


    In this study, a draft of human factors engineering (HFE) safety review procedures (SRP) was developed for the safety review of KNGR based on HFE Safety and Regulatory Requirements and Guidelines (SRRG). This draft includes acceptance criteria, review procedure, and evaluation findings for the areas of review including HFE Program Management, Human Factors Analyses, Human Factors Design, and HFE Verification and Validation, based on Section 15.1 'Human Factors Engineering Design Process' and 15.2 'Control Room Human Factors Engineering' of KNGR Specific Safety Requirements and Chapter 15 'Human Factors Engineering' of KNGR Safety Regulatory Guides. For the effective review, human factors concerns or issues related to advanced HSI design that have been reported so far should be extensively examined. In this study, a total of 384 human factors issues related to the advanced HSI design were collected through our review of a total of 145 documents. A summary of each issue was described and the issues were identified by specific features of HSI design. These results were implemented into a database system. 8 refs., 2 figs. (Author)

  11. Commentary: Implications, Themes, and Next Steps (United States)

    Nagayama Hall, Gordon C.


    The author presents a commentary on a special issue of the "Journal of College Counseling". The articles included in the issue describe the mental health needs and counseling center utilization patterns of the diverse population of college students. The establishment of the Center for Collegiate Mental Health has created the opportunity to study…

  12. Development of real-time diagnostics and feedback algorithms for JET in view of the next step

    Energy Technology Data Exchange (ETDEWEB)

    Murari, A [Consorzio RFX-Associazione EURATOM ENEA per la Fusione, Corso Stati Uniti 4, I-35127, Padua (Italy); Joffrin, E [Association EURATOM-CEA, CEA Cadarache, 13108 Saint-Paul-lez-Durance (France); Felton, R [Euratom/UKAEA Fusion Assoc., Culham Science Centre, Abingdon, Oxon, OX14 3DB (United Kingdom); Mazon, D [Association EURATOM-CEA, CEA Cadarache, 13108 Saint-Paul-lez-Durance (France); Zabeo, L [Euratom/UKAEA Fusion Assoc., Culham Science Centre, Abingdon, Oxon, OX14 3DB (United Kingdom); Albanese, R [Assoc. Euratom-ENEA-CREATE, Univ. Mediterranea RC, Loc. Feo di Vito, I-89060, RC (Italy); Arena, P [Assoc. Euratom-ENEA-CREATE, Univ. di Catania (Italy); Ambrosino, G [Assoc. Euratom-ENEA-CREATE, Univ. Napoli Federico II, Via Claudio 21, I-80125 Naples (Italy); Ariola, M [Assoc. Euratom-ENEA-CREATE, Univ. Napoli Federico II, Via Claudio 21, I-80125 Napoli (Italy); Barana, O [Consorzio RFX-Associazione EURATOM ENEA per la Fusione, Corso Stati Uniti 4, I-35127, Padua (Italy); Bruno, M [Assoc. Euratom-ENEA-CREATE, Univ. di Catania (Italy); Laborde, L [Association EURATOM-CEA, CEA Cadarache, 13108 Saint-Paul-lez-Durance (France); Moreau, D [Association EURATOM-CEA, CEA Cadarache, 13108 Saint-Paul-lez-Durance (France); Piccolo, F [Euratom/UKAEA Fusion Assoc., Culham Science Centre, Abingdon, Oxon, OX14 3DB (United Kingdom); Sartori, F [Euratom/UKAEA Fusion Assoc., Culham Science Centre, Abingdon, Oxon, OX14 3DB (United Kingdom); Crisanti, F [Associazone EURATOM ENEA sulla Fusione, C.R. Frascati (Italy); Luna, E de la [Associacion EURATOM CIEMAT para Fusion, Avenida Complutense 22, E-28040 Madrid (Spain); Sanchez, J [Associacion EURATOM CIEMAT para Fusion, Avenida Complutense 22, E-28040 Madrid (Spain)


    Real-time control of many plasma parameters will be an essential aspect in the development of reliable high performance operation of next step tokamaks. The main prerequisites for any feedback scheme are the precise real-time determination of the quantities to be controlled, requiring top quality and highly reliable diagnostics, and the availability of robust control algorithms. A new set of real-time diagnostics was recently implemented on JET to prove the feasibility of determining, with high accuracy and time resolution, the most important plasma quantities. Some of the signals now routinely provided in real time at JET are: (i) the internal inductance and the main confinement quantities obtained by calculating the Shafranov integrals from the pick-up coils with 2 ms time resolution; (ii) the electron temperature profile, from electron cyclotron emission every 10 ms; (iii) the ion temperature and plasma toroidal velocity profiles, from charge exchange recombination spectroscopy, provided every 50 ms; and (iv) the safety factor profile, derived from the inversion of the polarimetric line integrals every 2 ms. With regard to feedback algorithms, new model-based controllers were developed to allow a more robust control of several plasma parameters. With these new tools, several real-time schemes were implemented, among which the most significant is the simultaneous control of the safety factor and the plasma pressure profiles using the additional heating systems (LH, NBI, ICRH) as actuators. The control strategy adopted in this case consists of a multi-variable model-based technique, which was implemented as a truncated singular value decomposition of an integral operator. This approach is considered essential for systems like tokamak machines, characterized by a strong mutual dependence of the various parameters and the distributed nature of the quantities, the plasma profiles, to be controlled. First encouraging results were also obtained using non

  13. Next Step in Chronic Kidney Disease Therapy

    Directory of Open Access Journals (Sweden)

    D.D. Ivanov


    Full Text Available Angiotensin-converting enzyme inhibitors/angiotensin receptor blockers are the basis of renoprotection therapy in chronic kidney disease. Parallel to decrease of glomerular filtration rate, there is an increase in the activity of the sympathetic nervous system, and the number of functio­ning nephrons reduces, which requires a change of treatment regimen. Reducing the risk of cardiovascular events on the background of increased hypertension probably dictates the need for a priority administration of sympatholytics, calcium channel blockers and angiotensin-converting enzyme inhibitors/angiotensin receptor blockers withdrawal. ARAMONEL formula: ARAMONEL — AR(BA(CEIMO(xonidineNE(bivololL(ercandipine is changed to MNELD — M(oxonidineNE(bivololL(ercandipineD(iuretic that is used by us in recent years. Combined use of torsemide and xipamide is allowed. Angiotensin-converting enzyme inhibitors/angiotensin receptor blockers withdrawal requires evidence, which may be obtained in STOP-ACEi trial.

  14. Next Step Mobile: Strategy, Services, & PRM (United States)

    Thomas, Lisa Carlucci


    As emerging information technologies have driven demand for new library communication channels, there has been increased interest in the use of mobile tools to promote interaction, expand outreach, market programs, and enhance the library experience. Libraries today are at widely different levels of mobile engagement, a gap poised to grow as…

  15. Next steps in propositional horn contraction

    CSIR Research Space (South Africa)

    Booth, R


    Full Text Available not opted for this choice.) Our start- ing point for defining Horn e-contraction is in terms of Del- grande’s definition of e-remainder sets. Definition 3.1 (Horn e-Remainder Sets) For a belief setH , X ∈ H ↓e Φ iff (i) X ⊆ H , (ii) X 6|= Φ, and (iii...) for every X ′ s.t. X ⊂ X ′ ⊆ H , X ′ |= Φ. We refer to the elements of H ↓eΦ as the Horn e-remainder sets of H w.r.t. Φ. It is easy to verify that all Horn e-remainder sets are belief sets. Also, H ↓eΦ = ∅ iff |= Φ. We now proceed to define selection...

  16. Direct Taxation in the Eu: The Common Corporate Tax Base as the Next Sub-Step towards Harmonization

    Directory of Open Access Journals (Sweden)

    Norbert Herzig


    Full Text Available This paper analyzes the Common Corporate Tax Base (CCTB as an interim alternative to the proposal of a Council directive on a Common Consolidated Corporate Tax Base (CCCTB. The CCCTB concept does not only include common rules for determining the tax base like the CCTB but also the steps of consolidation and subsequent formula apportionment. Therefore, the paper starts by showing that particularly these second and third steps of the CCCTB project meet fierce political opposition from several Member States and do leave leeway for tax planning. Afterwards, the CCCTB proposal's approach to common rules for determining the tax base is evaluated, i.e. tested for its suitability as a point of departure for drafting a CCTB. Finally, various other aspects of the proposal are examined in light of a CCTB without consolidation.

  17. Experimental investigation of the 30S(α, p thermonuclear reaction in x-ray bursts

    Directory of Open Access Journals (Sweden)

    Kahl D.


    Full Text Available We performed the first measurement of 30S+α resonant elastic scattering to experimentally examine the 30S(α, p stellar reaction rate in type I x-ray bursts. These bursts are the most frequent thermonuclear explosions in the galaxy, resulting from thermonuclear runaway on the surface of accreting neutron star binaries. The 30S(α, p reaction plays a critical role in burst models, yet very little is known about the compound nucleus 34Ar at these energies nor the reaction rate itself. We performed a measurement of alpha elastic scattering with a radioactive beam of 30S to experimentally probe the entrance channel. Utilizing a gaseous active target system and silicon detector array, we extracted the excitation function from 1.8 to 5.5 MeV near 160° in the center-of-mass frame. The experimental data were analyzed with an R-Matrix calculation, and we discovered several new resonances and extracted their quantum properties (resonance energy, width, spin, and parity. Finally, we calculated the narrow resonant thermonuclear reaction rate of 30S(α, p for these new resonances.

  18. Next Generation Steam Cracking Reactor Concept

    NARCIS (Netherlands)

    Van Goethem, M.W.M.


    The steam cracking process is an important asset in the hydrocarbon processing industry. The main products are lower olefins and hydrogen, with ethylene being the world's largest volume organic chemical at a worldwide capacity of ~ 120 million tonnes per year. Feed stocks are hydrocarbons such as:

  19. Developing and validating advanced divertor solutions on DIII-D for next-step fusion devices (United States)

    Guo, H. Y.; Hill, D. N.; Leonard, A. W.; Allen, S. L.; Stangeby, P. C.; Thomas, D.; Unterberg, E. A.; Abrams, T.; Boedo, J.; Briesemeister, A. R.; Buchenauer, D.; Bykov, I.; Canik, J. M.; Chrobak, C.; Covele, B.; Ding, R.; Doerner, R.; Donovan, D.; Du, H.; Elder, D.; Eldon, D.; Lasa, A.; Groth, M.; Guterl, J.; Jarvinen, A.; Hinson, E.; Kolemen, E.; Lasnier, C. J.; Lore, J.; Makowski, M. A.; McLean, A.; Meyer, B.; Moser, A. L.; Nygren, R.; Owen, L.; Petrie, T. W.; Porter, G. D.; Rognlien, T. D.; Rudakov, D.; Sang, C. F.; Samuell, C.; Si, H.; Schmitz, O.; Sontag, A.; Soukhanovskii, V.; Wampler, W.; Wang, H.; Watkins, J. G.


    A major challenge facing the design and operation of next-step high-power steady-state fusion devices is to develop a viable divertor solution with order-of-magnitude increases in power handling capability relative to present experience, while having acceptable divertor target plate erosion and being compatible with maintaining good core plasma confinement. A new initiative has been launched on DIII-D to develop the scientific basis for design, installation, and operation of an advanced divertor to evaluate boundary plasma solutions applicable to next step fusion experiments beyond ITER. Developing the scientific basis for fusion reactor divertor solutions must necessarily follow three lines of research, which we plan to pursue in DIII-D: (1) Advance scientific understanding and predictive capability through development and comparison between state-of-the art computational models and enhanced measurements using targeted parametric scans; (2) Develop and validate key divertor design concepts and codes through innovative variations in physical structure and magnetic geometry; (3) Assess candidate materials, determining the implications for core plasma operation and control, and develop mitigation techniques for any deleterious effects, incorporating development of plasma-material interaction models. These efforts will lead to design, installation, and evaluation of an advanced divertor for DIII-D to enable highly dissipative divertor operation at core density (n e/n GW), neutral fueling and impurity influx most compatible with high performance plasma scenarios and reactor relevant plasma facing components (PFCs). This paper highlights the current progress and near-term strategies of boundary/PMI research on DIII-D.

  20. International Cooperation for the next 50 years: The International Project on Innovative Reactors and Fuel Cycles (INPRO)

    Energy Technology Data Exchange (ETDEWEB)

    Kupitz, J.; Steur, R.; Depisch, F. [IAEA, Wagramerstrasse 5, PF 100, 1400 Vienna (Austria)]. e-mail:


    During the last fifty years remarkable results are achieved in the application of nuclear technology for the production of electricity. Looking ahead to the next fifty years it is clear that the demand for energy will grow considerably and also the requirements for the way the energy will be supplied. Within INPRO the future of the energy demand and supply was explored and several scenario's identified. A leading requirement for energy supply is coming up and will play a crucial role: sustainability of the way the energy supply will be realized. Fulfilling the growing need for energy in developing countries is as well an important issue. Based on these scenario's for the next fifty years, an inventory of requirements for the future of nuclear energy systems has been collected as well a methodology developed by INPRO to assess innovative nuclear systems and fuel cycles. On the base of this assessment, the need for innovations and breakthroughs in existing technology can be defined. To facilitate the deployment of innovative nuclear systems also the infrastructure, technical as well institutional has to be adjusted to the anticipated changes in the world such as the globalization. As a contribution to the conference the main messages of INPRO will be presented. (Author)

  1. Next Steps Forward in Understanding Martian Surface and Subsurface Chemistry (United States)

    Carrier, Brandi L.


    The presence of oxidants such as hydrogen peroxide (H2O2) and perchlorate (ClO4-), which have been detected on Mars, has significant implications for chemistry and astrobiology. These oxidants can increase the reactivity of the Martian soil, accelerate the decomposition of organic molecules, and depress the freezing point of water. The study by Crandall et al. "Can Perchlorates be Transformed to Hydrogen Peroxide Products by Cosmic Rays on the Martian Surface" reveals a new formation mechanism by which hydrogen peroxide and other potential oxidants can be generated via irradiation of perchlorate by cosmic rays. This study represents an important next step in developing a full understanding of Martian surface and subsurface chemistry, particularly with respect to degradation of organic molecules and potential biosignatures.

  2. FIRE, A Next Step Option for Magnetic Fusion

    Energy Technology Data Exchange (ETDEWEB)

    Meade, D.M.


    The next major frontier in magnetic fusion physics is to explore and understand the strong nonlinear coupling among confinement, MHD stability, self-heating, edge physics, and wave-particle interactions that is fundamental to fusion plasma behavior. The Fusion Ignition Research Experiment (FIRE) Design Study has been undertaken to define the lowest cost facility to attain, explore, understand, and optimize magnetically confined fusion-dominated plasmas. The FIRE is envisioned as an extension of the existing Advanced Tokamak Program that could lead to an attractive magnetic fusion reactor. The FIRE activities have focused on the physics and engineering assessment of a compact, high-field tokamak with the capability of achieving Q approximately equal to 10 in the ELMy H-mode for a duration of about 1.5 plasma current redistribution times (skin times) during an initial burning-plasma science phase, and the flexibility to add Advanced Tokamak hardware (e.g., lower-hybrid current drive) later. The configuration chosen for FIRE is similar to that of ARIES-RS, the U.S. Fusion Power Plant study utilizing an Advanced Tokamak reactor. The key ''Advanced Tokamak'' features are: strong plasma shaping, double-null pumping divertors, low toroidal field ripple (<0.3%), internal control coils, and space for wall stabilization capabilities. The reference design point is R subscript ''o'' = 2.14 m, a = 0.595 m, B subscript ''t''(R subscript ''o'') = 10 T, I subscript ''p'' = 7.7 MA with a flattop time of 20 s for 150 MW of fusion power. The baseline magnetic fields and pulse lengths can be provided by wedged BeCu/OFHC toroidal-field (TF) coils and OFHC poloidal-field (PF) coils that are pre-cooled to 80 K prior to the pulse and allowed to warm up to 373 K at the end of the pulse. A longer-term goal of FIRE is to explore Advanced Tokamak regimes sustained by noninductive current drive

  3. After the flood is before the next flood - post event review of the Central European Floods of June 2013. Insights, recommendations and next steps for future flood prevention (United States)

    Szoenyi, Michael; Mechler, Reinhard; McCallum, Ian


    In early June 2013, severe flooding hit Central and Eastern Europe, causing extensive damage, in particular along the Danube and Elbe main watersheds. The situation was particularly severe in Eastern Germany, Austria, Hungary and the Czech Republic. Based on the Post Event Review Capability (PERC) approach, developed by Zurich Insurance's Flood Resilience Program to provide independent review of large flood events, we examine what has worked well (best practice) and opportunities for further improvement. The PERC overall aims to thoroughly examine aspects of flood resilience, flood risk management and catastrophe intervention in order to help build back better after events and learn for future events. As our research from post event analyses shows a lot of losses are in fact avoidable by taking the right measures pre-event and these measures are economically - efficient with a return of 4 Euro on losses saved for every Euro invested in prevention on average (Wharton/IIASA flood resilience alliance paper on cost benefit analysis, Mechler et al. 2014) and up to 10 Euros for certain countries. For the 2013 flood events we provide analysis on the following aspects and in general identify a number of factors that worked in terms of reducing the loss and risk burden. 1. Understanding risk factors of the Central European Floods 2013 We review the precursors leading up to the floods in June, with an extremely wet May 2013 and an atypical V-b weather pattern that brought immense precipitation in a very short period to the watersheds of Elbe, Donau and partially the Rhine in the D-A-CH countries and researched what happened during the flood and why. Key questions we asked revolve around which protection and risk reduction approaches worked well and which did not, and why. 2. Insights and recommendations from the post event review The PERC identified a number of risk factors, which need attention if risk is to be reduced over time. • Yet another "100-year flood" - risk

  4. a New Approach of the Deflagration to Detonation Transition in SNIa Thermonuclear Supernovae (United States)

    Chièze, Jean Pierre; Charignon, Camille


    A wide class of type Ia thermonuclear supernovae models relies on the transition from the subsonic deflagration combustion regime to the supersonic detonation regime of the carbon and oxygen mixture of an accreting white dwarf, near the Chandrasekhar mass. We show that this can actually be achieved in a cold C+O white dwarf near the Chandrasekhar mass, with seed sound waves of relatively low Mach number M ˜ 0.02. Moreover, even weaker perturbations, with velocity perturbations as low as M ˜ 0.003 can trigger a detonation wave in SNIa progenitors models wich include the presence of a thin helium surface layer.

  5. The Effect of Screening Factors and Thermonuclear Reaction Rates ...

    Indian Academy of Sciences (India)

    In understanding the nucleosynthesis of the elements in stars, one of the most important quantities is the reaction rate and it must be evaluated in terms of the stellar temperature , and its determination involves the knowledge of the excitation function () of the specific nuclear reaction leading to the final nucleus. In this ...

  6. The effects of vacuum polarization on thermonuclear reaction rates (United States)

    Gould, Robert J.


    Added to the pure Coulomb potential, the contribution from vacuum polarization increases the barrier, reducing the wave function (u) for reacting nuclei within the range of nuclear forces. The cross section and reaction rate are then reduced accordingly by a factor proportional to u squared. The effect is treated by evaluating the vacuum polarization potential as a small correction to the Coulomb term, then computing u in a WKB formulation. The calculation is done analytically employing the small r power-series expansion for the Uehling potential to express the final result in terms of convenient parameters. At a temperature of 1.4 x 10 to the 7th K the (negative) correction is 1.3 percent for the fundamental fusion process p + p yields d + e(+) + nu.

  7. A Game Theoretic Model of Thermonuclear Cyberwar

    Energy Technology Data Exchange (ETDEWEB)

    Soper, Braden C. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)


    In this paper we propose a formal game theoretic model of thermonuclear cyberwar based on ideas found in [1] and [2]. Our intention is that such a game will act as a first step toward building more complete formal models of Cross-Domain Deterrence (CDD). We believe the proposed thermonuclear cyberwar game is an ideal place to start on such an endeavor because the game can be fashioned in a way that is closely related to the classical models of nuclear deterrence [4–6], but with obvious modifications that will help to elucidate the complexities introduced by a second domain. We start with the classical bimatrix nuclear deterrence game based on the game of chicken, but introduce uncertainty via a left-of-launch cyber capability that one or both players may possess.

  8. Clinical data related to breast reconstruction; looking back on the 21th century and forward to the next steps

    Directory of Open Access Journals (Sweden)

    Jecan Cristian Radu


    Full Text Available Breast reconstruction after breast cancer surgery represents a positive step in restoring a women’s idea of self by reestablishing her feminine features and confidence, thus improving essential aesthetic and emotional aspects. Regarded as the cornerstone in breast cancer management, the surgical treatment has come a long way since 1884 when W.S. Halsted performed the first radical mastectomy- a disfiguring procedure which was conducted until the late 70s when owing to contemporary advancements it was surpassed by modified radical mastectomies and other far less invasive approaches. Either performed in an immediate or a delayed fashion breast reconstruction can be achieved not only through alloplastic procedures using expander/ implant prosthesis but also through autologous tissue transfers wisely harvested from different parts of the body or through methods that combine the two. When planning a breast reconstruction, after the oncologist formally rules out any form of residual cancer, one must take into consideration several critical factors that will eventually condition the technique election process for example the possible local or systemic adjuvant therapy. Although a “one size fits all” breast reconstruction procedure has yet to prevail, the extensive volume of published literature regarding this matter enables a well-experienced plastic surgeon to proceed with careful procedural selection allowing for the best possible results.

  9. Quantifying Reliability - The Next Step for a Rapidly Maturing PV Industry and China's Role

    Energy Technology Data Exchange (ETDEWEB)

    Kurtz, Sarah


    PV customers wish to know how long their PV modules will last, but quantitatively predicting service life is difficult because of the large number of ways that a module can fail, the variability of the use environment, the cost of the testing, and the short product development time, especially when compared with the long desired lifetime. China should play a key role in developing international standards because China manufactures most of the world's PV modules. The presentation will describe the steps that need to be taken to create a service life prediction within the context of a defined bill of materials, process window and use environment. Worldwide standards for cost-effective approaches to service-life predictions will be beneficial to both PV customers and manufacturers since the consequences of premature module failure can be disastrous for both.

  10. Physics of thermo-nuclear fusion and the ITER project; La physique de la fusion thermonucleaire et le projet ITER

    Energy Technology Data Exchange (ETDEWEB)

    Garin, P. [CEA Cadarache, Dept. de Recherches sur la Fusion Controlee - DRFC, 13 - Saint-Paul-lez-Durance (France)


    This document gathers the slides of the 6 contributions to the workshop 'the physics of thermo-nuclear fusion and the ITER project': 1) the feasibility of magnetic confinement and the issue of heat recovery, 2) heating and current generation in tokamaks, 3) the physics of wall-plasma interaction, 4) recent results at JET, 5) inertial confinement and fast ignition, and 6) the technology of fusion machines based on magnetic confinement. This document presents the principles of thermo-nuclear fusion machines and gives a lot of technical information about JET, Tore-Supra and ITER.

  11. The TDF System for Thermonuclear Plasma Reaction Rates, Mean Energies and Two-Body Final State Particle Spectra

    Energy Technology Data Exchange (ETDEWEB)

    Warshaw, S I


    The rate of thermonuclear reactions in hot plasmas as a function of local plasma temperature determines the way in which thermonuclear ignition and burning proceeds in the plasma. The conventional model approach to calculating these rates is to assume that the reacting nuclei in the plasma are in Maxwellian equilibrium at some well-defined plasma temperature, over which the statistical average of the reaction rate quantity {sigma}v is calculated, where {sigma} is the cross-section for the reaction to proceed at the relative velocity v between the reacting particles. This approach is well-understood and is the basis for much nuclear fusion and astrophysical nuclear reaction rate data. The Thermonuclear Data File (TDF) system developed at the Lawrence Livermore National Laboratory (Warshaw 1991), which is the topic of this report, contains data on the Maxwellian-averaged thermonuclear reaction rates for various light nuclear reactions and the correspondingly Maxwellian-averaged energy spectra of the particles in the final state of those reactions as well. This spectral information closely models the output particle and energy distributions in a burning plasma, and therefore leads to more accurate computational treatments of thermonuclear burn, output particle energy deposition and diagnostics, in various contexts. In this report we review and derive the theoretical basis for calculating Maxwellian-averaged thermonuclear reaction rates, mean particle energies, and output particle spectral energy distributions for these reactions in the TDF system. The treatment of the kinematics is non-relativistic. The current version of the TDF system provides exit particle energy spectrum distributions for two-body final state reactions only. In a future report we will discuss and describe how output particle energy spectra for three- and four-body final states can be developed for the TDF system. We also include in this report a description of the algorithmic implementation of the

  12. Efficiency calculations and optimization analysis of a solar reactor for the high temperature step of the zinc/zinc-oxide thermochemical redox cycle

    Energy Technology Data Exchange (ETDEWEB)

    Haussener, S.


    A solar reactor for the first step of the zinc/zinc-oxide thermochemical redox cycle is analysed and dimensioned in terms of maximization of efficiency and reaction conversion. Zinc-oxide particles carried in an inert carrier gas, in our case argon, enter the reactor in absorber tubes and are heated by concentrated solar radiation mainly due to radiative heat transfer. The particles dissociate and, in case of complete conversion, a gas mixture of argon, zinc and oxygen leaves the reactor. The aim of this study is to find an optimal design of the reactor regarding efficiency, materials and economics. The number of absorber tubes and their dimensions, the cavity dimension and its material as well as the operating conditions should be determined. Therefore 2D and 3D simulations of an 8 kW reactor are implemented. The gases are modeled as ideal gases with temperature-dependent properties. Absorption and scattering of the particle gas mixture are calculated by Mie-theory. Radiative heat transfer is included in the simulation and implemented with the aid of the discrete ordinates (DO) method. The mixture is modeled as ideal mixture and the reaction with an Arrhenius-type ansatz. Temperature distribution, reaction efficiency (heat used for zinc-oxide reaction divided by input) and tube efficiency (heat going into absorber tubes divided by input) as well as reaction conversion are analyzed to find the most promising reactor design. The results show that the most significant factors for efficiencies, conversion and absorber fluid temperature are concentration of the solar incoming radiation, zinc-oxide mass flow, the number of tubes and their dimension. Higher concentration leads to solely positive effects. Zinc-oxide mass flow variations indicate the existence of an optimal flow rate for each reactor design which maximizes efficiencies and conversion. Higher zinc-oxide mass flow leads, on one hand, to higher tube efficiency but on the other hand to lower temperatures in

  13. Group Health Coaching: Strengths, Challenges, and Next Steps (United States)

    Wolever, Ruth Q.; Manning, Linda; Elam, Roy; Moore, Margaret; Frates, Elizabeth Pegg; Duskey, Heidi; Anderson, Chelsea; Curtis, Rebecca L.; Masemer, Susan; Lawson, Karen


    There is great need for cost effective approaches to increase patient engagement and improve health and well-being. Health and wellness coaching has recently demonstrated great promise, but the majority of studies to date have focused on individual coaching (ie, one coach with one client). Newer initiatives are bringing a group coaching model from corporate leadership development and educational settings into the healthcare arena. A group approach potentially increases cost-effective access to a larger number of clients and brings the possible additional benefit of group support. This article highlights some of the group coaching approaches currently being conducted across the United States. The group coaching interventions included in this overview are offered by a variety of academic and private sector institutions, use both telephonic and in-person coaching, and are facilitated by professionally trained health and wellness coaches as well as trained peer coaches. Strengths and challenges experienced in these efforts are summarized, as are recommendations to address those challenges. A working definition of “Group Health and Wellness Coaching” is proposed, and important next steps for research and for the training of group coaches are presented. PMID:24416678

  14. Radiation effects and tritium technology for fusion reactors. Volume I. Proceedings of the international conference, Gatlinburg, Tennessee, October 1--3, 1975

    Energy Technology Data Exchange (ETDEWEB)

    Watson, J.S.; Wiffen, F.W.; Bishop, J.L.; Breeden, B.K. (eds.)


    Separate abstracts were prepared for the 29 included papers in Vol. I. The topics covered in this volume include swelling and microstructures in thermonuclear reactor materials. Some papers on modeling and damage analysis are included. (MOW)

  15. Crossing the Next Frontier (United States)

    Goldston, R.; Menard, J.; Brooks, J.; Doerner, R.; Gates, D.; Fu, G.-Y.; Gorelenkov, N.; Kaita, R.; Kaye, S.; Kramer, G.; Kugel, H.; Majeski, R.; Ono, M.; Skinner, C.; Strachan, J.; Harris, J.; Maingi, R.; Kotschenreuther, M.; Mahajan, S.; Valanju, P.; Nygren, R.; Ulrickson, M.; Ruzic, D.; Sabbagh, S.; Soukhanovskii, V.


    The plasma-material interface is the next frontier in fusion science. ITER's approaches to heat flux and tritium retention do not extrapolate to Demo. Defining questions at this frontier include: Can extremely high radiated-power fraction be consistent with high confinement and low Zeff? Can magnetic flux expansion or edge ergodization reduce heat loads sufficiently? Can tungsten survive with acceptable core radiation and tritium retention? Can liquid metals more effectively handle high heat flux, off-normal loads and tritium exhaust? Answers must be integrated with high-performance, fully steady state plasma operation, avoiding ELMs and eliminating disruptions. The vehicle to cross this frontier is a high-power-density plasma with long pulses, excellent diagnostic access, flexible first wall, divertor, heating, current drive and plasma control systems, extensive deuterium and trace tritium operation, and the ability to test a range of plasma-facing materials at reactor-relevant temperature.

  16. Placing the power of real options analysis into the hands of natural resource managers - taking the next step. (United States)

    Nelson, Rohan; Howden, Mark; Hayman, Peter


    This paper explores heuristic methods with potential to place the analytical power of real options analysis into the hands of natural resource managers. The complexity of real options analysis has led to patchy or ephemeral adoption even by corporate managers familiar with the financial-market origins of valuation methods. Intuitively accessible methods for estimating the value of real options have begun to evolve, but their evaluation has mostly been limited to researcher-driven applications. In this paper we work closely with Bush Heritage Australia to evaluate the potential of real options analysis to support the intuitive judgement of conservation estate managers in covenanting land with uncertain future conservation value due to climate change. The results show that modified decision trees have potential to estimate the option value of covenanting individual properties while time and ongoing research resolves their future conservation value. Complementing this, Luehrman's option space has potential to assist managers with limited budgets to increase the portfolio value of multiple properties with different conservation attributes. Copyright © 2013 Elsevier Ltd. All rights reserved.

  17. Analysis of the Thermonuclear Instability including Low-Power ICRH Minority Heating in IGNITOR

    CERN Document Server

    Cardinali, Alessandro


    The nonlinear thermal balance equation for classical plasma in a toroidal geometry is analytically and numerically investigated including ICRH power. The determination of the equilibrium temperature and the analysis of the stability of the solution are performed by solving the energy balance equation that includes the transport relations obtained by the kinetic theory. An estimation of the confinement time is also provided. We show that the ICRH heating in the IGNITOR experiment, among other applications, is expected to stabilize the power of the thermonuclear burning by automatic regulation of the RF coupled power. Here a scenario is considered where IGNITOR is led to operate in a slightly sub-critical regime by adding a small fraction of ${}^3He$ to the nominal 50-50 Deuterium-Tritium mixture. The difference between power lost and alpha heating is compensated by additional ICRH heating, which should be able to increase the global plasma temperature via collisions between ${}^3He$ minority and the background...

  18. The Fermi-GBM X-Ray Burst Monitor: Thermonuclear Bursts from 4U 0614+09

    NARCIS (Netherlands)

    Linares, M.; Connaughton, V.; Jenke, P.; van der Horst, A.J.; Camero-Arranz, A.; Kouveliotou, C.; Chakrabarty, D.; Beklen, E.; Bhat, P.N.; Briggs, M.S.; Finger, M.; Paciesas, W.S.; Preece, R.; von Kienlin, A.; Wilson-Hodge, C.A.


    Thermonuclear bursts from slowly accreting neutron stars (NSs) have proven difficult to detect, yet they are potential probes of the thermal properties of the NS interior. During the first year of a systematic all-sky search for X-ray bursts using the Gamma-ray Burst Monitor aboard the Fermi

  19. Removal of the veterinary antimicrobial sulfamethazine in a horizontal-flow anaerobic immobilized biomass (HAIB) reactor subjected to step changes in the applied organic loading rate. (United States)

    Oliveira, G H D; Santos-Neto, A J; Zaiat, M


    A bench-scale horizontal-flow anaerobic immobilized biomass (HAIB) reactor treating synthetic swine wastewater was operated under different applied organic loading rates (OLR) through both variations in feed strength and in hydraulic retention time (HRT). The influence of step changes in OLR on the removal of the veterinary antimicrobial sulfamethazine (SMZ) was assessed. The highest observed SMZ removal efficiency, 75 ± 6%, was achieved with an OLR of 2.7 ± 0.4 kg O 2  m -3  d -1 when a significant increase in COD removal rate was observed. The SMZ removal rate was positively correlated (r = 0.899) to the COD removal rate in all of the experimental conditions in which the HRT was kept at 24 h, indicating a cometabolic transformation of the antimicrobial. Decreasing the HRT caused a significant decrease in SMZ removal efficiency without affecting the HAIB reactor performance in terms of stability, COD removal or metabolic intermediates production. Functionally equivalent steady states were observed in four different operational phases with similar operating conditions but with widely different behavior in relation to SMZ removal. The experimental results showed the potential of anaerobic technology in removing environmentally relevant concentrations of SMZ, and the possibility of enhancing reactor performance by controlling operating conditions. Copyright © 2017 Elsevier Ltd. All rights reserved.

  20. Next Steps to Implement Renewable Energy Project on the Makah Indian Naiton for the Pacific North West Region

    Energy Technology Data Exchange (ETDEWEB)

    Martin Wilde, Coyote Energy, Inc.


    The two year feasibility project was conducted to determine if the Makah reservation wind resource is viable for commercial generation and to investigate the viability and implementaiton of a tribal utility company capable of conducting energy business on the reservation.

  1. Expression of OCT4A: The First Step to the Next Stage of Urothelial Bladder Cancer Progression

    Directory of Open Access Journals (Sweden)

    Wojciech Jóźwicki


    Full Text Available OCT4 (octamer-binding transcription factor is a transcription factor responsible for maintaining the pluripotent properties of embryonic stem cells. In this paper, we present the results of studies to investigate the role of the OCT4 splicing variant in urothelial bladder cancer and the relationship between the OCT4 phenotype and the morphological parameters of tumor malignancy. Ninety patients who received a cystectomy for bladder cancer were enrolled. The expression of OCT4 protein was analyzed by immunohistochemistry. The ratio of OCT4-positive cells was the lowest in pT1 (pathological assessment (p—tumor extent confined to mucosa (T1 tumors and the highest in pTis (non-papillary tumor extent confined to urothelium and pT2 (tumor extent including muscularis propria tumors. Information about the percentage of OCT4A-positive tumor cells could facilitate choosing the treatment mode in borderline pTis–pT1 (crossing the border of the basement membrane; the first stage of progression and pT1–pT2 (crossing the border of the muscularis propria; the second stage of progression cases: a higher percentage of OCT4A-positive cells should support more radical therapy. A significantly higher percentage of cases with moderate OCT4 intensity was found in metastasizing (the third stage of progression cases with >2 positive lymph nodes. The percentage of OCT4-positive cells was significantly higher for cancers with a high grade, higher non-classic differentiation number and greater aggressiveness of invasion. The differentiation, maturation and aggressiveness of tumor invasion appear to depend on the expression of the OCT4 phenotype in cancer cells, similar to the successive stages of malignancy progression in urothelial cancer.

  2. Next steps in access and availability of opioids for the treatment of cancer pain: reaching the tipping point? (United States)

    Cleary, J; Radbruch, L; Torode, J; Cherny, N I


    The reports of the Global Opioid Policy Initiative (GOPI) project to evaluate the availability and accessibility of opioids for the management of cancer pain in Africa, Asia, Latin America and the Caribbean, and the Middle East, together with the previous 2010 European Society for Medical Oncology (ESMO)/European Association for Palliative Care (EAPC) report from Europe, have provided critical data in demonstrating the deficiencies in many countries throughout the world. Formulary deficiencies and over-regulation are pandemic and must be addressed. This process is challenging and will require concerted and sustained efforts by clinical leaders and advocacy groups partnering with international and regional organizations and, of course, with national governments and their competent authorities. There is a growing international expertise and infrastructure to coordinate advocacy and strategic planning based on the World Health Organization (WHO) Model of Education, Policy Reform and Medication Availability.

  3. The next step in the treatment of persistent temporomandibular joint pain following arthrocentesis: a retrospective study of 18 cases. (United States)

    Emes, Y; Arpınar, I Ş; Oncü, B; Aybar, B; Aktaş, I; Al Badri, N; Atalay, B; Işsever, H; Yalçın, S


    Temporomandibular joint disorders affect a big portion of the population. There are a variety of treatment methods currently in use. Conservative treatment modalities are followed by more invasive approaches like arthrocentesis or arthroscopy. The aim of the study is to compare the effects of intra-articular tenoxicam injection and arthrocentesis plus viscosupplementation on patients in which a previous arthrocentesis plus viscosupplementation has failed to relieve pain and restore function. The study group consists of 18 TMJs in 16 patients (15 female and 1 male) and the patients were randomly divided into two groups as the arthrocentesis plus viscosupplementation group (n: 8) and tenoxicam injection (n: 10). 20 mg of tenoxicam was injected to the upper compartments of 10 joints without arthrocentesis. The other 8 joints were treated with a second arthrocentesis and sodium hyaluronate injection. VAS scores and maximum mouth opening with and without assistance were recorded in the post operative first week, first month and third month. The results show that there is little benefit in using relatively conservative methods once an arthrocentesis together with viscosupplementation has failed to relieve the patients pain. It is concluded that more invasive procedures should be considered for the patients who do not benefit from arthrocentesis. Copyright © 2013 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved.

  4. The Next Steps in Developing the Triple Helix Model: A Brief Introduction to National Open Innovation System (NOIS Paradigm

    Directory of Open Access Journals (Sweden)

    Teemu Santonen


    Full Text Available On the basis of beliefs on open innovation, online social networks and Web 2.0, we propose a new type of approach based on people-to-people interaction to support national innovation activities. With the aim of generating new ideas, our National Open Innovation System (NOIS combines two rival innovation sources: (1 technology and social foresight research, and (2 customer needs and experiences (i.e. customer orientation strategy, while following the principles of latest incarnation of Triple Helix model. The resulting NOIS is an effective and comprehensive open innovation structure where university students and senior citizens are engaged as a significant resource for the business community, in order to fulfil the national innovation strategy as defined by the government.

  5. Studying bubble-induced methane emissions from the East Siberian Arctic Shelf: the next step towards a quantitative assessment. (United States)

    Chernykh, D.; Shakhova, N. E.; Semiletov, I. P.; Yusupov, V.; Salomatin, A.; Leifer, I.


    Destabilization of subsea permafrost results in increasing permeability for gaseous methane long preserved in seabed deposits within and beneath permafrost. This process manifests as extensive methane ebullition, driving significantly elevated methane aqueous concentrations - up to three orders higher than atmospheric equilibrium. In places, bubbles release as a vigorous flow that often reach the surface; on echograms, such bubble plums create specific flare-like images. To detect, map, monitor, and analyze bubble-induced methane fluxes, in summer 2011 and 2012, sonar data were gathered over extensive seep fields in the East Siberian Arctic Shelf (ESAS) in frame of International Siberian Shelf Study (ISSS). To measure the bubble screen backscattering strength, the acoustic sensors were calibrated using a target ("ideal" sphere) provided by the manufacturer (SIMRAD). To establish a relationship between the backscattering strength of bubbles releasing from the seafloor and methane flux rate, an in-situ calibration using engineered seeps was performed. To apportion fraction of bubbles reaching the sea surface and assess remaining gaseous content of bubbles, in winter 2011-2013, direct in-situ observations of bubbles, ascending from the seafloor, were performed using high-speed high-resolution video camera. Results of inter-calibration between engineered quantitative in-situ calibrations and qualitative calibration recommended by manufacturer were applied to evaluate bubble-induced methane fluxes observed in the ESAS in summer 2011 and 2012.

  6. Managing the Innovation Process: Infusing Data Analytics into the Undergraduate Business Curriculum (Lessons Learned and Next Steps) (United States)

    Wymbs, Cliff


    The designing of a new, potentially disruptive, curricular program, is not without challenges; however, it can be rewarding for students, faculty, and employers and serve as a template for other academics to follow. To be effective, the new data analytics program should be driven by business input and academic leadership that incorporates…

  7. A comparison of radioactive waste from first generation fusion reactors and fast fission reactors with actinide recycling

    Energy Technology Data Exchange (ETDEWEB)

    Koch, M.; Kazimi, M.S.


    Limitations of the fission fuel resources will presumably mandate the replacement of thermal fission reactors by fast fission reactors that operate on a self-sufficient closed fuel cycle. This replacement might take place within the next one hundred years, so the direct competitors of fusion reactors will be fission reactors of the latter rather than the former type. Also, fast fission reactors, in contrast to thermal fission reactors, have the potential for transmuting long-lived actinides into short-lived fission products. The associated reduction of the long-term activation of radioactive waste due to actinides makes the comparison of radioactive waste from fast fission reactors to that from fusion reactors more rewarding than the comparison of radioactive waste from thermal fission reactors to that from fusion reactors. Radioactive waste from an experimental and a commercial fast fission reactor and an experimental and a commercial fusion reactor has been characterized. The fast fission reactors chosen for this study were the Experimental Breeder Reactor 2 and the Integral Fast Reactor. The fusion reactors chosen for this study were the International Thermonuclear Experimental Reactor and a Reduced Activation Ferrite Helium Tokamak. The comparison of radioactive waste parameters shows that radioactive waste from the experimental fast fission reactor may be less hazardous than that from the experimental fusion reactor. Inclusion of the actinides would reverse this conclusion only in the long-term. Radioactive waste from the commercial fusion reactor may always be less hazardous than that from the commercial fast fission reactor, irrespective of the inclusion or exclusion of the actinides. The fusion waste would even be far less hazardous, if advanced structural materials, like silicon carbide or vanadium alloy, were employed.

  8. Novel test-bed facility for PSI issues in fusion reactor conditions on the base of next generation QSPA plasma accelerator (United States)

    Garkusha, I. E.; Chebotarev, V. V.; Herashchenko, S. S.; Makhlaj, V. A.; Kulik, N. V.; Ladygina, M. S.; Marchenko, A. K.; Petrov, Yu. V.; Staltsov, V. V.; Shevchuk, P. V.; Solyakov, D. G.; Yelisyeyev, D. V.


    In this report a concept of a new generation QSPA with external B-field up to 2 T has been discussed. A novel test-bed facility, which was recently constructed in Kharkov IPP NSC KIPT, has been described. It allows for a new level of plasma stream parameters and its wide variation in new QSPA-M device, as well as possible combination of steady-state and pulsed plasma loads to the materials during the exposures. First plasma is recently obtained. Careful optimization of the operational regimes of the plasma accelerator’s functional components and plasma dynamics in the magnetic system of QSPA-M device has started approaching step by step the necessary level of plasma parameters and their effective variation. The relevant results on plasma stream characterization are presented. Energy density distributions in plasma stream have been measured with calorimetry. Spectroscopy and probe technique have also been applied for plasma parameters measurements. The obtained results demonstrate the ability of QSPA-M to reproduce the ELM impacts in fusion reactor, both in terms of heat load and particle flux to the surface.

  9. Igniting the Light Elements: The Los Alamos Thermonuclear Weapon Project, 1942-1952

    Energy Technology Data Exchange (ETDEWEB)

    Fitzpatrick, Anne C. [Virginia Polytechnic Inst. and State Univ. (Virginia Tech), Blacksburg, VA (United States)


    The American system of nuclear weapons research and development was conceived and developed not as a result of technological determinism, but by a number of individual architects who promoted the growth of this large technologically-based complex. While some of the technological artifacts of this system, such as the fission weapons used in World War II, have been the subject of many historical studies, their technical successors--fusion (or hydrogen) devices--are representative of the largely unstudied highly secret realms of nuclear weapons science and engineering. In the postwar period a small number of Los Alamos Scientific Laboratory's staff and affiliates were responsible for theoretical work on fusion weapons, yet the program was subject to both the provisions and constraints of the US Atomic Energy Commission, of which Los Alamos was a part. The Commission leadership's struggle to establish a mission for its network of laboratories, least of all to keep them operating, affected Los Alamos's leaders' decisions as to the course of weapons design and development projects. Adapting Thomas P. Hughes's ''large technological systems'' thesis, I focus on the technical, social, political, and human problems that nuclear weapons scientists faced while pursuing the thermonuclear project, demonstrating why the early American thermonuclear bomb project was an immensely complicated scientific and technological undertaking. I concentrate mainly on Los Alamos Scientific Laboratory's Theoretical, or T, Division, and its members' attempts to complete an accurate mathematical treatment of the ''Super''--the most difficult problem in physics in the postwar period--and other fusion weapon theories. Although tackling a theoretical problem, theoreticians had to address technical and engineering issues as well. I demonstrate the relative value and importance of H-bomb research over time in the postwar era to

  10. Summary of small group discussions: Regional themes and next steps (United States)

    Rick Turner


    At the conclusion of the workshop, a breakout group session discussed common themes that had emerged regarding forest degradation monitoring in the Southeast Asia region. The participants were also asked to list any important issues that may not have been sufficiently addressed during the workshop and that may require further discussion, and recommendations for next...

  11. High Performance Fuel Desing for Next Generation Pressurized Water Reactors

    Energy Technology Data Exchange (ETDEWEB)

    Mujid S. Kazimi; Pavel Hejzlar


    The use of internally and externally cooled annular fule rods for high power density Pressurized Water Reactors is assessed. The assessment included steady state and transient thermal conditions, neutronic and fuel management requirements, mechanical vibration issues, fuel performance issues, fuel fabrication methods and econmic assessment. The investigation was donducted by a team from MIT, Westinghouse, Gamma Engineering, Framatome ANP, and AECL. The analyses led to the conclusion that raising the power density by 50% may be possible with this advanced fuel. Even at the 150% power level, the fuel temperature would be a few hundred degrees lower than the current fuel temperatre. Significant economic and safety advantages can be obtained by using this fuel in new reactors. Switching to this type of fuel for existing reactors would yield safety advantages, but the economic return is dependent on the duration of plant shutdown to accommodate higher power production. The main feasiblity issue for the high power performance appears to be the potential for uneven splitting of heat flux between the inner and outer fuel surfaces due to premature closure of the outer fuel-cladding gap. This could be overcome by using a very narrow gap for the inner fuel surface and/or the spraying of a crushable zirconium oxide film at the fuel pellet outer surface. An alternative fuel manufacturing approach using vobropacking was also investigated but appears to yield lower than desirable fuel density.

  12. Pacific Northwest Laboratory report on controlled thermonuclear reactor technology, October 1975 - December 1975. [Fusion-fission hybrid systems research

    Energy Technology Data Exchange (ETDEWEB)



    Survey calculations are being made on three blanket configurations for a conceptual hybrid design based on a Two Component Torus (TCT) in a cooperative effort between Princeton Plasma Physics Laboratory (PPPL) and PNL. Other studies are underway to provide background data in the design of a minimum thickness shield and a convertor region for the TCT hybrid. The effect the plasma and associated radiation and emission will have upon the surfaces of the first wall are being studied. A variety of metal targets were prepared for neutron irradiation and were evaluated. Radioactive recoil sputtering ratios are summarized with complete results being prepared for separate publication. The development and testing of the ion blistering equipment is continuing with the design and installation of a special differential pumping stage. Analysis of the molybdenum specimens irradiated for the initial BCC ion correlation experiment is completed and data from the participants have been compared. Graphite cloth and fibers irradiated in EBR-II to approximately 3 x 10/sup 21/ cm/sup -2/ at approximately 500/sup 0/C are being evaluated for radiation damage effects. Helium effects are being studied on five alloys specified in CTR conceptual designs. Tests were designed to determine the effects of oxidation potential on low-level contaminant/metal interactions. Niobium and vanadium are being studied for mechanical property effects after injection of helium by the tritium trick method. An advanced state-of-the-art Acoustics Emission Event Energy Analyzer (AEEEA) has been developed and tested.

  13. Development of technology for next generation reactor - Research of evaluation technology for nuclear power plant -

    Energy Technology Data Exchange (ETDEWEB)

    Park, Jong Kyun; Chang, Moon Heuy; Hwang, Yung Dong [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of)] [and others


    For development of next generation reactor, a project for evaluation technology for nuclear power plant is performed. Evaluation technology is essential to next generation reactor for reactor safety and system analysis. For design concept, detailed evaluation technologies are studied as follows: evaluation of safety margin, evaluation of safety facilities, evaluation of measurement and control technology; man-machine interface. Especially for thermal efficiency, thermal properties and chemical composition of inconel 690 tube, instead of inconel 600 tube, are measured for steam generator. (Author).

  14. What's Next After You Say Hello: First Steps in Mentoring (United States)

    Hogue, William F.; Pringle, Ernest M.


    In most cultures wisdom, knowledge, and experience are prized assets. Those who possess them are held in high regard and are expected to share them with the next generation. So it is in the world of information technology (IT). Veteran IT professionals are often charged with identifying and developing future IT leaders, while future leaders often…

  15. The mechanics in the reactors physics; La mecanique dans la physique des reacteurs

    Energy Technology Data Exchange (ETDEWEB)

    Barral, J.C. [Electricite de France (EDF), 75 - Paris (France); Zaetta, A. [CEA/Cadarache, Dept. d' Etudes des Reacteurs, DER/SPRC, 13 - Saint-Paul-lez-Durance (France); Johner, J. [CEA/Cadarache, Dept. de Recherches sur la Fusion Controlee, DRFC, 13 - Saint-Paul-lez-Durance (France)] [and others


    This meeting of the 24 november 1998, took place in Paris and was organized by the SFEN. After three plenary sessions a technical meeting dealt on the mechanics in reactors physics. The plenary papers presented the state of the art in the PWR type reactors and fast neutron reactors systems and in the thermonuclear reactors system. Five more technical papers presented the seismic behavior of the reactors cores, the fuel-cladding interactions, the defects harmfulness in the fracture mechanics and the fuel rods control system wear. (A.L.B.)

  16. Design scoping study of the 12T Yin-Yang magnet system for the Tandem Mirror Next Step (TMNS). Final report

    Energy Technology Data Exchange (ETDEWEB)


    The overall objective of this engineering study was to determine the feasibility of designing a Yin-Yang magnet capable of producing a peak field in the windings of 12T for the Tandem Mirror Next Step (TMNS) program. As part of this technical study, a rough order of magnitude (ROM) cost estimate of the winding for this magnet was undertaken. The preferred approach to the winding design of the TMNS plug coil utilizes innovative design concepts to meet the structural, electrical and thermodynamic requirements of the magnet system. Structurally, the coil is radially partitioned into four sections, preventing the accumulation of the radial loads and reacting them into the structural case. To safely dissipate the 13.34 GJ of energy stored in each Yin-Yang magnet, the winding has been electrically subdivided into parallel or nested coils, each having its own power supply and protection circuitry. This arrangement effectively divides the total stored energy of the coils into manageable subsystems. The windings are cooled with superfluid helium II, operated at 1.8K and 1.2 atmospheres. The superior cooling capabilities of helium II have enabled the overall winding envelope to be minimized, providing a current density of 2367 A/CM/sup 2/, excluding substructure.

  17. Polyacrylamide Ferrogels with Magnetite or Strontium Hexaferrite: Next Step in the Development of Soft Biomimetic Matter for Biosensor Applications

    Directory of Open Access Journals (Sweden)

    Alexander P. Safronov


    Full Text Available Magnetic biosensors are an important part of biomedical applications of magnetic materials. As the living tissue is basically a “soft matter.” this study addresses the development of ferrogels (FG with micron sized magnetic particles of magnetite and strontium hexaferrite mimicking the living tissue. The basic composition of the FG comprised the polymeric network of polyacrylamide, synthesized by free radical polymerization of monomeric acrylamide (AAm in water solution at three levels of concentration (1.1 M, 0.85 M and 0.58 M to provide the FG with varying elasticity. To improve FG biocompatibility and to prevent the precipitation of the particles, polysaccharide thickeners—guar gum or xanthan gum were used. The content of magnetic particles in FG varied up to 5.2 wt % depending on the FG composition. The mechanical properties of FG and their deformation in a uniform magnetic field were comparatively analyzed. FG filled with strontium hexaferrite particles have larger Young’s modulus value than FG filled with magnetite particles, most likely due to the specific features of the adhesion of the network’s polymeric subchains on the surface of the particles. FG networks with xanthan are stronger and have higher modulus than the FG with guar. FG based on magnetite, contract in a magnetic field 0.42 T, whereas some FG based on strontium hexaferrite swell. Weak FG with the lowest concentration of AAm shows a much stronger response to a field, as the concentration of AAm governs the Young’s modulus of ferrogel. A small magnetic field magnetoimpedance sensor prototype with Co68.6Fe3.9Mo3.0Si12.0B12.5 rapidly quenched amorphous ribbon based element was designed aiming to develop a sensor working with a disposable stripe sensitive element. The proposed protocol allowed measurements of the concentration dependence of magnetic particles in gels using magnetoimpedance responses in the presence of magnetite and strontium hexaferrite ferrogels

  18. Beyond the Black-White Binary of U.S. Race Relations: A Next Step in Religious Education (United States)

    Goto, Courtney T.


    Many if not most people in the academy as well as the public sphere tend to regard race and racism in the United States in terms of a default frame of reference (i.e., a paradigm): the black-white binary. Although this frame is constructive as well as compelling, it displays serious liabilities. This article outlines, for religious educators, nine…

  19. Literature review : Use of family history for primary paediatric care as the next step towards use of genomics in healthcare

    NARCIS (Netherlands)

    Syurina, Elena V.; Hens, Kristien; Feron, Frans J M


    Introduction: Many childhood-onset diseases and developmental disorders have a strong genetic basis. However, up till now, the knowledge of this genetic component within multifactorial diseases is not frequently used in paediatric practice. A good family history collection can facilitate the link

  20. Integrated, multi-scale, spatial-temporal cell biology--A next step in the post genomic era. (United States)

    Horwitz, Rick


    New microscopic approaches, high-throughput imaging, and gene editing promise major new insights into cellular behaviors. When coupled with genomic and other 'omic information and "mined" for correlations and associations, a new breed of powerful and useful cellular models should emerge. These top down, coarse-grained, and statistical models, in turn, can be used to form hypotheses merging with fine-grained, bottom up mechanistic studies and models that are the back bone of cell biology. The goal of the Allen Institute for Cell Science is to develop the top down approach by developing a high throughput microscopy pipeline that is integrated with modeling, using gene edited hiPS cell lines in various physiological and pathological contexts. The output of these experiments and models will be an "animated" cell, capable of integrating and analyzing image data generated from experiments and models. Copyright © 2015 Elsevier Inc. All rights reserved.

  1. Next steps for meeting the needs of people with severe mental illness in low- and middle-income countries. (United States)

    Hanlon, C


    The explicit inclusion of mental health within the Sustainable Development Goals is a welcome development, borne out of powerful advocacy using public health, economic and human rights arguments. As funding comes on line for scale-up of evidence-based mental health care by task-sharing with primary care, it is time to take stock about care for people affected by severe mental illness (SMI). The existing evidence base for task shared care for SMI provides an imperative to get started, but is skewed towards relatively more affluent and urban populations in middle-income countries where specialist mental health professionals provide most of the care. Randomised, controlled trials and rigorous implementation research on task shared service models are underway which will go some way to improving understanding of the quality, safety, effectiveness and acceptability of more widely generalisable care for people with SMI. A sub-group of people with SMI have more complex and long-term needs for care, with a high risk of homelessness, imprisonment and human rights violations as family and social supports become overwhelmed. Case studies from non-governmental organisations provide examples of holistic approaches to rehabilitation, recovery and empowerment of people with SMI, but rigorous comparative studies are needed to identify the most efficient, effective and scalable approaches to care. Health system constraints are emerging as the over-riding barriers to successful task-sharing, highlighting a need to develop and evaluate chronic care models for people with SMI that succeed in reducing premature mortality, improving wellbeing and achieving better social outcomes. Addressing these evidence gaps is essential if task-sharing mental health care is going to deliver on its promise of promoting recovery for the full range of people affected by SMI.

  2. The effects of variations in nuclear interactions on nucleosynthesis in thermonuclear supernovae (United States)

    Parikh, A.; José, J.; Seitenzahl, I. R.; Röpke, F. K.


    Context. Type Ia supernova explosions are violent stellar events important for their contribution to the cosmic abundance of iron peak elements and for their role as cosmological distance indicators. Aims: The impact of nuclear physics uncertainties on nucleosynthesis in thermonuclear supernovae has not been fully explored using comprehensive and systematic studies with multiple models. To better constrain predictions of yields from these phenomena, we investigate thermonuclear reaction rates and weak interaction rates that significantly affect yields in our underlying models. Methods: We have performed a sensitivity study by postprocessing thermodynamic histories from two different hydrodynamic, Chandrasekhar-mass explosion models. We have individually varied all input reaction and, for the first time, weak interaction rates by a factor of ten (up and down) and compared the yields in each case to yields using standard rates. Results: Of the 2305 nuclear reactions in our network, we find that in either model the rates of only 53 reactions affect the yield of any species with an abundance of at least 10-8 M⊙ by at least a factor of two. The rates of the 12C(α,γ), 12C+12C, 20Ne(α,p), 20Ne(α,γ), and 30Si(p,γ) reactions are among those that modify the most yields when varied by a factor of ten. From the individual variation of 658 weak interaction rates in our network by a factor of ten, only the stellar 28Si(β+)28Al, 32S(β+)32P, and 36Ar(β+)36Cl rates significantly affect the yields of species in a model. Additional tests reveal that reaction rate changes over temperatures T > 1.5 GK have the greatest impact and that ratios of radionuclides that may be used as explosion diagnostics change by a factor of ≲2 from the variation of individual rates by a factor of ten. Conclusions: Nucleosynthesis in the two adopted models is relatively robust to variations in individual nuclear reaction and weak interaction rates. Laboratory measurements of a limited number

  3. Don Bloch's vision for Collaborative Family Health Care: Progress and next steps. (United States)

    Peek, C J


    Don Bloch is the central figure in the origin story for the field of collaborative family health care; the journal Families, Systems, & Health; and for the Collaborative Family Healthcare Association (CFHA). He exerted extraordinary intellectual and practical leadership for all 3. He convened a national working session in 1994 that took stock of the field and set out next steps, one of which was to create the interprofessional organization dedicated to collaborative family health care that is now CFHA. As part of honoring Don Bloch's contributions to the field and this journal, this article sets out tenets of his original vision and traces next steps toward this vision generated by national groups between 1994 and 2014, showing what is the same or different over these 20 years, and especially what this means for the field going forward. Precepts of Don Bloch's original vision are drawn from his writings, including the briefing papers he prepared for the national Wingspread group convened in 1994, which also set out next steps for the field. These steps are then compared with next developmental steps for the field generated by CFHA conference attendees in 2004 and again in 2014, after reviewing the history of the organization and the field. Much of Don Bloch's vision has remained relevant to health care transformation, with a number of areas showing significant accomplishment and acceptance, whereas others remain aspirational, and a few others arguably being more difficult to achieve now than when Don articulated them. (c) 2015 APA, all rights reserved).

  4. Approximating the r-Process on Earth with Thermonuclear Explosions. Lessons Learned and Unanswered Questions

    Energy Technology Data Exchange (ETDEWEB)

    Becker, Stephen Allan [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)


    During the astrophysical r-process, multiple neutron captures occur so rapidly on target nuclei that their daughter nuclei generally do not have time to undergo radioactive decay before another neutron is captured. The r-process can be approximately simulated on Earth in certain types of thermonuclear explosions through an analogous process of rapid neutron captures known as the "prompt capture" process. Between 1952 and 1969, 23 nuclear tests were fielded by the US which were involved (at least partially) with the "prompt capture" process. Of these tests, 15 were at least partially successful. Some of these tests were conducted under the Plowshare Peaceful Nuclear Explosion Program as scientific research experiments. It is now known that the USSR conducted similar nuclear tests during 1966 to 1979. The elements einsteinium and fermium were first discovered by this process. The most successful tests achieved 19 successive neutron captures on the initial target nuclei. A review of the US program, target nuclei used, heavy element yields, scientific achievements of the program, and how some of the results have been used by the astrophysical community is given. Finally, some unanswered questions concerning very neutron-rich nuclei that could potentially have been answered with additional nuclear experiments is presented.

  5. Numerical analysis of thermonuclear detonation in dense plasma (United States)

    Avronin, Y. N.; Bunatyan, A. A.; Gadzhiyev, A. D.; Mustafin, K. A.; Nurbakov, A. S.; Pisarev, V. N.; Feoktistov, L. P.; Frolov, V. D.; Shibarshov, L. I.


    The propagation of thermonuclear combustion from the region heated to thermonuclear temperatures by an external source to the remaining part of the target was investigated. The target was a tube of inert material (gold, lead, beryllium, etc.) filled with a deuterium-tritium mixture. It was determined analytically that thermonuclear combustion can propagate from a small portion of a nonspherical target to the remainder of the target and that a steady-state thermonuclear detonation wave can be formed. The role of various physical processes in thermonuclear detonation was investigated. Shock wave is the main mechanism underlying detonation propagation. The detonation rate and intensity of the thermonuclear reaction is influenced by the leakage of heat due to transvere heat conductivity. The critical diameter for thermonuclear detonation was determined approximately for a plasma filament encased in a housing with twice the density of the fuel.

  6. Next Steps for "Big Data" in Education: Utilizing Data-Intensive Research (United States)

    Dede, Chris


    Data-informed instructional methods offer tremendous promise for increasing the effectiveness of teaching, learning, and schooling. Yet-to-be-developed data science approaches have the potential to dramatically advance instruction for every student and to enhance learning for people of all ages. Next steps that emerged from a recent National…

  7. Design requirements of instrumentation and control systems for next generation reactor

    Energy Technology Data Exchange (ETDEWEB)

    Koo, In Soo; Lee, Byung Sun; Park, Kwang Hyun; Park, Heu Yoon; Lee, Dong Young; Kim, Jung Taek; Hwang, In Koo; Chung, Chul Hwan; Hur, Seop; Kim, Chang Hoi; Na, Nan Ju [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of)


    In this report, the basic design requirements of Instrumentation and Control systems for next generation reactor are described, which are top-tier level, to support the advanced I and C systems. It contains the requirements in accordance with the plant reliability, the plant performance, the operator`s aid functions, the features for maintenance and testing, licensing issues for I and C systems. Advanced I and C systems are characterized such as the application of the digital and the human engineering technologies. To development of this requirements, the I and C systems for the foreign passive and the evolutionary types of reactor and the domestic conventional reators were reviewed and anlysed. At the detail design stage, these requirements will be used for top-tier requirements. To develop the detail design requirements in the future, more quantitive and qualitive analyses are need to be added. (Author) 44 refs.

  8. Fusion reactor materials semiannual progress report for the period ending March 31, 1990

    Energy Technology Data Exchange (ETDEWEB)


    This report mainly discusses topics on the physical effects of radiation on thermonuclear reactor materials. The areas discussed are: irradiation facilities, test matrices, and experimental methods; dosimetry, damage parameters, and activation calculations; fundamental mechanical behavior; radiation effects; mechanistic studies, theory and modeling; development of structural alloys; solid breeding materials; and ceramics. (FI)

  9. Fusion reactor materials: Semiannual progress report for the period ending March 31, 1988

    Energy Technology Data Exchange (ETDEWEB)



    This report contains papers on thermonuclear reactor materials. The general categories of these papers are: irradiation facilities, test matrices, and experimental methods; dosimetry, damage parameters and activation calculations; materials engineering and design requirements; fundamental mechanical behavior; development of structural alloys; solid breeding materials; ceramics; and radiation effects. Selected papers have been processed for inclusion in the energy database. (LSP)

  10. Next steps for a Green Economy Working Group in Kazakhstan. Notes from the Astana Green Economy Dialogue, 24-26 November 2011

    Energy Technology Data Exchange (ETDEWEB)

    Ospanova, Saule; Wilson, Emma; Bass, Steve


    In the Republic of Kazakhstan, national concerns over today’s economic, social and environmental challenges have translated into sustainable development policy and initiatives such as the Astana Green Bridge Initiative. The Government of Kazakhstan has developed the Green Bridge Partnership Programme (GBPP), with the support of international organizations, for possible adoption at the Rio+20 World Sustainable Development Conference in June 2012. This programme offers opportunities for 'greening' the economy, with a focus on aspirations for regional and international technology cooperation and finance. it also offers potential for enhancing public participation in decision-making, and harmonising policies and practices across European, Asian and Pacific regions. A range of other initiatives are also ongoing within Kazakhstan, and it is important for those promoting these initiatives to join forces and engage in dialogue. The Astana Green Economy Dialogue, held from 24th to 26th November 2011, organised by IIED and the Kazakhstan Ministry for the Environment and supported by the UK Foreign and Commonwealth Office (FCO) and the Organisation for Security and Co-operation in Europe (OSCE), brought together a range of stakeholders from government, civil society and industry to discuss the notion of the green economy and how it can be applied and developed in Kazakhstan. The dialogue had a particular focus on the energy sector given its relevance. Oil-producing states face a global challenge to play their part in establishing economic systems that reduce climate change and other environmental burdens, and to produce higher societal value from limited natural resources. This short report summarises the key observations and ideas discussed at the workshop, with recommendations for next steps and follow up. It is meant to provide a record of the discussions that took place at this dialogue and provides a foundation for further work.

  11. (Near-Infrared) Fluorescence-Guided Surgery Under Ambient Light Conditions: A Next Step to Embedment of the Technology in Clinical Routine. (United States)

    van den Berg, Nynke S; Miwa, Mitsuharu; KleinJan, Gijs H; Sato, Takayuki; Maeda, Yoshiki; van Akkooi, Alexander C J; Horenblas, Simon; Karakullukcu, Baris; van Leeuwen, Fijs W B


    In open surgery procedures, after temporarily dimming the lights in the operation theatre, the Photo Dynamic Eye (PDE) fluorescence camera has, amongst others, been used for fluorescence-guided sentinel node (SN) biopsy procedures. To improve the clinical utility and logistics of fluorescence-guided surgery, we developed and evaluated a prototype modified PDE (m-PDE) fluorescence camera system. The m-PDE works under ambient light conditions and includes a white light mode and a pseudo-green-colored fluorescence mode (including a gray-scaled anatomical background). Twenty-seven patients scheduled for SN biopsy for (head and neck) melanoma (n = 16), oral cavity (n = 6), or penile (n = 5) cancer were included. The number and location of SNs were determined following an indocyanine green-(99m)Tc-nanocolloid injection and preoperative imaging. Intraoperatively, fluorescence guidance was used to visualize the SNs. The m-PDE and conventional PDE were compared head-to-head in a phantom study, and in seven patients. In the remaining 20 patients, only the m-PDE was evaluated. Phantom study: The m-PDE was superior over the conventional PDE, with a detection sensitivity of 1.20 × 10(-11) M (vs. 3.08 × 10(-9) M) ICG in human serum albumin. In the head-to-head clinical comparison (n = 7), the m-PDE was also superior: (i) SN visualization: 100 versus 81.4 %; (ii) transcutaneous SN visualization: 40.7 versus 22.2 %; and (iii) lymphatic duct visualization: 7.4 versus 0 %. Findings were further underlined in the 20 additionally included patients. The m-PDE enhanced fluorescence imaging properties compared with its predecessor, and provides a next step towards routine integration of real-time fluorescence guidance in open surgery.

  12. FROM THE HISTORY OF PHYSICS: The physics of a thermonuclear explosion of a normal-density liquefied deuterium sphere (On the impossibility of a spherically symmetric thermonuclear explosion in liquid deuterium at normal density) (United States)

    Marchuk, Gurii I.; Imshennik, Vladimir S.; Basko, Mikhail M.


    The hydrodynamic problem of a thermonuclear explosion in a sphere of normal-density liquid deuterium was solved (Institute for Physics and Power Engineering, Obninsk) in 1952-1954 in the framework of the Soviet Atomic Project. The principal result was that the explosion shockwave in deuterium strongly decayed because of radiation energy loss and nonlocal energy release by fast neutrons. At that time, this negative result implied in essence that the straightforward approach to creating a thermonuclear weapon was in fact a blind alley. This paper describes a numerical solution to the stated problem, obtained with the modern DEIRA code developed for numerical modeling of inertially confined fusion. Detailed numerical calculations have confirmed the above 'historic' result and shed additional light on the physical causes of the detonation wave decay. The most pernicious factor is the radiation energy loss due to the combined effect of bremsstrahlung and the inverse Compton scattering of the emitted photons on the hot electrons. The impact of energy transfer by fast neutrons — which was already quite adequately accounted for in the above-cited historical work — is less significant. We present a more rigorous (compared to that of the 1950s) study of the role of inverse Compton scattering for which, in particular, an independent analytic estimate is obtained.


    Energy Technology Data Exchange (ETDEWEB)

    Linares, M.; Chakrabarty, D. [Massachusetts Institute of Technology, Kavli Institute for Astrophysics and Space Research, Cambridge, MA 02139 (United States); Connaughton, V.; Bhat, P. N.; Briggs, M. S.; Preece, R. [CSPAR and Physics Department, University of Alabama in Huntsville, Huntsville, AL 35899 (United States); Jenke, P.; Kouveliotou, C.; Wilson-Hodge, C. A. [Space Science Office, VP62, NASA/Marshall Space Flight Center, Huntsville, AL 35812 (United States); Van der Horst, A. J. [Astronomical Institute ' Anton Pannekoek' , University of Amsterdam, NL-1090-GE Amsterdam (Netherlands); Camero-Arranz, A.; Finger, M.; Paciesas, W. S. [Universities Space Research Association, Huntsville, AL 35805 (United States); Beklen, E. [Physics Department, Suleyman Demirel University, 32260 Isparta (Turkey); Von Kienlin, A. [Max Planck Institute for Extraterrestrial Physics, Giessenbachstrasse, Postfach 1312, D-85748 Garching (Germany)


    Thermonuclear bursts from slowly accreting neutron stars (NSs) have proven difficult to detect, yet they are potential probes of the thermal properties of the NS interior. During the first year of a systematic all-sky search for X-ray bursts using the Gamma-ray Burst Monitor aboard the Fermi Gamma-ray Space Telescope we have detected 15 thermonuclear bursts from the NS low-mass X-ray binary 4U 0614+09 when it was accreting at nearly 1% of the Eddington limit. We measured an average burst recurrence time of 12 {+-} 3 days (68% confidence interval) between 2010 March and 2011 March, classified all bursts as normal duration bursts and placed a lower limit on the recurrence time of long/intermediate bursts of 62 days (95% confidence level). We discuss how observations of thermonuclear bursts in the hard X-ray band compare to pointed soft X-ray observations and quantify such bandpass effects on measurements of burst radiated energy and duration. We put our results for 4U 0614+09 in the context of other bursters and briefly discuss the constraints on ignition models. Interestingly, we find that the burst energies in 4U 0614+09 are on average between those of normal duration bursts and those measured in long/intermediate bursts. Such a continuous distribution in burst energy provides a new observational link between normal and long/intermediate bursts. We suggest that the apparent bimodal distribution that defined normal and long/intermediate duration bursts during the last decade could be due to an observational bias toward detecting only the longest and most energetic bursts from slowly accreting NSs.

  14. Comparison of the Recently proposed Super Marx Generator Approach to Thermonuclear Ignition with the DT Laser Fusion-Fission Hybrid Concept (LIFE) by the Lawrence Livermore National Laboratory. (United States)

    Winterberg, Friedwardt


    The recently proposed Super Marx pure deuterium micro-detonation ignition concept [1] is compared to the Lawrence Livermore National Ignition Facility (NIF) laser DT fusion-fission hybrid concept (LIFE) [2]. A typical example of the LIFE concept is a fusion gain 30, and a fission gain of 10, making up for a total gain of 300, with about 10 times more energy released into fission as compared to fusion. This means a substantial release of fission products, as in fusion-less pure fission reactors. In the Super Marx approach for the ignition of a pure deuterium micro-detonation gains of the same magnitude can in theory be reached. If the theoretical prediction can be supported by more elaborate calculations, the Super Marx approach is likely to make lasers obsolete as a means for the ignition of thermonuclear micro-explosions. [1] ``Ignition of a Deuterium Micro-Detonation with a Gigavolt Super Marx Generator,'' Winterberg, F., Journal of Fusion Energy, Springer, 2008. [2] ``LIFE: Clean Energy from Nuclear Waste,'';for&_slash;the&_slash;future/life/

  15. Neutron star cooling and the rp process in thermonuclear X-ray bursts (United States)

    in't Zand, J. J. M.; Visser, M. E. B.; Galloway, D. K.; Chenevez, J.; Keek, L.; Kuulkers, E.; Sánchez-Fernández, C.; Wörpel, H.


    When the upper layer of an accreting neutron star experiences a thermonuclear runaway of helium and hydrogen, it exhibits an X-ray burst of a few keV with a cool-down phase of typically 1 min. When there is a surplus of hydrogen, hydrogen fusion is expected to simmer during that same minute due to the rp process, which consists of rapid proton captures and slow β-decays of proton-rich isotopes. We have analyzed the high-quality light curves of 1254X-ray bursts, obtained with the Proportional Counter Array on the Rossi X-ray Timing Explorer between 1996 and 2012, to systematically study the cooling and rp process. This is a follow-up of a study on a selection of 37 bursts from systems that lack hydrogen and show only cooling during the bursts. We find that the bolometric light curves are well described by the combination of a power law and a one-sided Gaussian. The power-law decay index is between 1.3 and 2.1 and similar to that for the 37-bursts sample. There are individual bursters with a narrower range. The Gaussian is detected in half of all bursts, with a typical standard deviation of 50 s and a fluence ranging up to 60% of the total fluence. The Gaussian appears consistent with being due to the rp process. The Gaussian fluence fraction suggests that the layer where the rp process is active is underabundant in H by a factor of at least five with respect to cosmic abundances. Ninety-four percent of all bursts from ultracompact X-ray binaries lack the Gaussian component, and the remaining 6% are marginal detections. This is consistent with a hydrogen deficiency in these binaries. We find no clear correlation between the power law and Gaussian light-curve components. Full Table C.1 is only available at the CDS via anonymous ftp to ( or via

  16. REACH: next step to a sound chemicals management. (United States)

    Van der Wielen, Arnold


    REACH is the new European Regulation for Registration, Evaluation, Authorisation and Restriction of Chemicals. It entered into force on 1st June 2007 to streamline and improve the former legislative framework on new and on existing chemical substances of the European Union. Companies which manufacture or import more than 1 tonne of a substance per year will be required to register the substance at the new EU Chemicals Agency located in Helsinki. REACH places greater responsibility on industry to manage the risks that chemicals may pose to the health and the environment and to provide safety information that will be passed down the supply chain. In principle, REACH applies to all chemicals as such, as components in preparations and as used in articles. REACH is a radical step forward in the EU chemicals management. The onus will move from the authorities to industry. In addition, REACH will allow the further evaluation of substances where there are grounds for concern, foresees an authorisation system for the use of substances of very high concern and a system of restrictions, where applicable, for substances of concern. The Authorisation system will require companies to switch progressively to safer alternatives where a suitable alternative exists. Current use restrictions will remain under REACH system.

  17. Next Generation Nuclear Plant Project Technology Development Roadmaps: The Technical Path Forward for 750–800°C Reactor Outlet Temperature

    Energy Technology Data Exchange (ETDEWEB)

    John Collins


    This document presents the NGNP Critical PASSCs and defines their technical maturation path through Technology Development Roadmaps (TDRMs) and their associated Technology Readiness Levels (TRLs). As the critical PASSCs advance through increasing levels of technical maturity, project risk is reduced and the likelihood of within-budget and on-schedule completion is enhanced. The current supplier-generated TRLs and TDRMs for a 750–800°C reactor outlet temperature (ROT) specific to each supplier are collected in Appendix A.

  18. Cardiovascular risk in rheumatoid arthritis: assessment, management and next steps (United States)

    Zegkos, Thomas; Kitas, George; Dimitroulas, Theodoros


    Rheumatoid arthritis (RA) is associated with increased cardiovascular (CV) morbidity and mortality which cannot be fully explained by traditional CV risk factors; cumulative inflammatory burden and antirheumatic medication-related cardiotoxicity seem to be important contributors. Despite the acknowledgment and appreciation of CV disease burden in RA, optimal management of individuals with RA represents a challenging task which remains suboptimal. To address this need, the European League Against Rheumatism (EULAR) published recommendations suggesting the adaptation of traditional risk scores by using a multiplication factor of 1.5 if two of three specific criteria are fulfilled. Such guidance requires proper coordination of several medical specialties, including general practitioners, rheumatologists, cardiologists, exercise physiologists and psychologists to achieve a desirable result. Tight control of disease activity, management of traditional risk factors and lifestyle modification represent, amongst others, the most important steps in improving CV disease outcomes in RA patients. Rather than enumerating studies and guidelines, this review attempts to critically appraise current literature, highlighting future perspectives of CV risk management in RA. PMID:27247635

  19. CCLC Commission on the Future: An Update. Increasing College Preparation and Completion through Concurrent Enrollment--The Next Steps. 2020 Vision: Student Success (United States)

    Mize, R.


    Since the publication of the initial report of the League's Commission on the Future (COTF), there have been many reports written and the California Community Colleges have taken many steps to improve student success and completion. However, there is still much to do. This paper will provide a brief assessment of where we are--in relation to…

  20. Next Generation Nuclear Plant Reactor Pressure Vessel Materials Research and Development Plan (PLN-2803)

    Energy Technology Data Exchange (ETDEWEB)

    J. K. Wright; R. N. Wright


    The U.S. Department of Energy (DOE) has selected the High-Temperature Gas-cooled Reactor (HTGR) design for the Next Generation Nuclear Plant (NGNP) Project. The NGNP will demonstrate the use of nuclear power for electricity and hydrogen production, with an outlet gas temperature in the range of 750°C, and a design service life of 60 years. The reactor design will be a graphite-moderated, helium-cooled, prismatic, or pebble bed reactor and use low-enriched uranium, Tri-Isotopic (TRISO)-coated fuel. The plant size, reactor thermal power, and core configuration will ensure passive decay heat removal without fuel damage or radioactive material releases during accidents. Selection of the technology and design configuration for the NGNP must consider both the cost and risk profiles to ensure that the demonstration plant establishes a sound foundation for future commercial deployments. The NGNP challenge is to achieve a significant advancement in nuclear technology while setting the stage for an economically viable deployment of the new technology in the commercial sector soon after 2020. This technology development plan details the additional research and development (R&D) required to design and license the NGNP RPV, assuming that A 508/A 533 is the material of construction. The majority of additional information that is required is related to long-term aging behavior at NGNP vessel temperatures, which are somewhat above those commonly encountered in the existing database from LWR experience. Additional data are also required for the anticipated NGNP environment. An assessment of required R&D for a Grade 91 vessel has been retained from the first revision of the R&D plan in Appendix B in somewhat less detail. Considerably more development is required for this steel compared to A 508/A 533 including additional irradiation testing for expected NGNP operating temperatures, high-temperature mechanical properties, and extensive studies of long-term microstructural stability.

  1. The operational definition of a functional local public health agency: the next strategic step in the quest for identity and relevance. (United States)

    Lenihan, Patrick; Welter, Christina; Chang, Carol; Gorenflo, Grace


    In 2002, the National Association of County and City Health Officials embarked on a quest to clarify, in a uniform way, the functions of governmental local public health agencies. Over the next 3 years, a diverse group of local health department officials and their partners developed an Operational Definition of a Functional Local Health Department, which included 45 standards matched to the 10 Essential Services. These standards serve as the first comprehensive and uniform articulation of local health department activities for which 250 prototype metrics have subsequently been developed. This article articulates the historical and policy significance of the Operational Definition, the methodological development of the recently published prototype metrics, and presents ideas for use of the metric tool especially in light of current accreditation and quality improvement initiatives.

  2. Next Generation Nuclear Plant Reactor Pressure Vessel Materials Research and Development Plan (PLN-2803)

    Energy Technology Data Exchange (ETDEWEB)

    J. K. Wright; R. N. Wright


    The U.S. Department of Energy has selected the High Temperature Gas-cooled Reactor design for the Next Generation Nuclear Plant (NGNP) Project. The NGNP will demonstrate the use of nuclear power for electricity and hydrogen production. It will have an outlet gas temperature in the range of 900°C and a plant design service life of 60 years. The reactor design will be a graphite moderated, helium-cooled, prismatic, or pebble-bed reactor and use low-enriched uranium, Tri-Isotopic-coated fuel. The plant size, reactor thermal power, and core configuration will ensure passive decay heat removal without fuel damage or radioactive material releases during accidents. The NGNP Materials Research and Development Program is responsible for performing research and development on likely NGNP materials in support of the NGNP design, licensing, and construction activities. Selection of the technology and design configuration for the NGNP must consider both the cost and risk profiles to ensure that the demonstration plant establishes a sound foundation for future commercial deployments. The NGNP challenge is to achieve a significant advancement in nuclear technology while setting the stage for an economically viable deployment of the new technology in the commercial sector soon after 2020. Studies of potential Reactor Pressure Vessel (RPV) steels have been carried out as part of the pre-conceptual design studies. These design studies generally focus on American Society of Mechanical Engineers (ASME) Code status of the steels, temperature limits, and allowable stresses. Three realistic candidate materials have been identified by this process: conventional light water reactor RPV steels A508/533, 2¼Cr-1Mo in the annealed condition, and modified 9Cr 1Mo ferritic martenistic steel. Based on superior strength and higher temperature limits, the modified 9Cr-1Mo steel has been identified by the majority of design engineers as the preferred choice for the RPV. All of the vendors have

  3. The Next Step in Understanding Impaired Reactive Balance Control in People With Stroke: The Role of Defective Early Automatic Postural Responses

    NARCIS (Netherlands)

    Kam, D. de; Roelofs, J.M.B.; Bruijnes, A.; Geurts, A.C.; Weerdesteyn, V.G.M.


    BACKGROUND AND OBJECTIVE: Postural muscle responses are often impaired after stroke. We aimed to identify the contribution of deficits in very early postural responses to poorer reactive balance capacity, with a particular focus on reactive stepping as a key strategy for avoiding falls. METHODS: A

  4. The Next Arms Race (United States)


    sharp internal political crises, economic transforma- tion, social instability, demographic decline, and the collapse of conventional military power. The...continued domestic stability, the government may need to siphon resources from the military in favor of social spending programs. Finally, open pool-type light-wa- ter reactor (22.5 MWth) built by the Argentine firm INVAP ( Investigaciones Aplicadas), was in- augurated in 1998. Its fuel

  5. Supersymmetry: the Next Spectroscopy

    Energy Technology Data Exchange (ETDEWEB)

    Peskin, Michael E


    I describe the picture by which supersymmetry--the possible symmetry of Nature that converts fermions to bosons and vice versa--accounts for the next stage of physics beyond the Standard Model. I then survey the future experimental program implied by this theory, in which the spectrum of particles associated with supersymmetry will be determined with precision.

  6. The Next Great Science (United States)

    Hodges, K. V.


    Earth science --- when defined as the study of all biological, chemical, and physical processes that interact to define the behavior of the Earth system --- has direct societal relevance equal to or greater than that any other branch of science. However, "geology", "geoscience", and "Earth science" departments are contracting at many universities and even disappearing at some. This irony speaks volumes about the limitations of the traditional university structure that partitions educational and research programs into specific disciplines, each housed in its own department. Programs that transcend disciplinary boundaries are difficult to fit into the traditional structure and are thus highly vulnerable to threats such as chronic underfunding by university administrations, low enrollments in more advanced subjects, and being largely forgotten during capital campaigns. Dramatic improvements in this situation will require a different way of thinking about earth science programs by university administrations. As Earth scientists, our goal must not be to protect "traditional" geology departments, but rather to achieve a sustainable programmatic future for broader academic programs that focus on Earth evolution from past, present, and future perspectives. The first step toward meeting this goal must be to promote a more holistic definition of Earth science that includes modes of inquiry more commonly found in engineering and social science departments. We must think of Earth science as a meta-discipline that includes core components of physics, geology, chemistry, biology, and the emerging science of complexity. We must recognize that new technologies play an increasingly important role in our ability to monitor global environmental change, and thus our educational programs must include basic training in the modes of analysis employed by engineers as well as those employed by scientists. One of the most important lessons we can learn from the engineering community is the

  7. The Next Computer Revolution. (United States)

    Peled, Abraham


    Discusses some of the future trends in the use of the computer in our society, suggesting that computing is now entering a new phase in which it will grow exponentially more powerful, flexible, and sophisticated in the next decade. Describes some of the latest breakthroughs in computer hardware and software technology. (TW)

  8. Annual report of the Summit Members' Working Group on Controlled Thermonuclear Fusion (Fusin Working Group (FWG))

    Energy Technology Data Exchange (ETDEWEB)



    The Summit Members' Working Group on Controlled Thermonuclear Fusion (Fusion Working Group (FWG)) was established in 1983 in response to the Declaration of the Heads of State and Government at the Versailles Economic Summit meeting of 1982, and in response to the subsequent report of the Working Group in Technology, Growth and Employment (TGE) as endorsed at the Williamsburg Summit meeting, 1983. This document contains the complete written record of each of the three FWG meetings which include the minutes, lists of attendees, agendas, statements, and summary conclusions as well as the full reports of the Technical Working Party. In addition, there is a pertinent exchange of correspondence between FWG members on the role of the Technical Working Party and a requested background paper on the modalities associated with a possible future ETR project.

  9. Description of the effort sharing approaches as presented in the Ecofys' policy brief The next step in Europe's climate action. Setting targets for 2030

    Energy Technology Data Exchange (ETDEWEB)

    Hoehne, N.; Hagemann, M.; Fekete, H. [Ecofys, Utrecht (Netherlands)


    The paper 'The next step in Europe's climate action. Setting targets for 2030' explains how setting 2030 targets will reinvigorate the ETS and will put EU emissions on track to limit global temperature increase below two degrees Celsius (2C). The paper describes four key findings for EU policymakers engaged in preparing EU energy and climate measures for 2030 and for the longer term. This document aims to provide background information on the effort sharing approaches, as presented in fore-mentioned paper.

  10. Simulations of the Neutral-beam-induced Rotation, Radial Electric Field, and Flow Shearing Rate in Next-step Burning Plasmas

    Energy Technology Data Exchange (ETDEWEB)

    R.V. Budny


    Toroidal rotation of plasmas in present tokamaks is beneficial for increasing the stability to wall-induced MHD and appears to reduce the anomalous transport associated with micro-turbulence. This paper calculates the toroidal rotation expected from neutral-beam injection in the proposed FIRE and ITER-FEAT tokamak reactors. Self-consistent burning plasmas for these tokamaks have been constructed using the TRANSP plasma analysis code. Neutral-beam injection has been proposed for FIRE and ITER-FEAT. The neutral-beam-induced torques are computed, and assumptions for the anomalous transport of toroidal angular momentum are used to calculate the toroidal rotation profiles. The central Mach numbers are about 3-8%. The ratio of the rotation speed to the Alfvin speed is less than 1%. Assuming neoclassical poloidal rotation and force balance, the radial electric field and flow shearing rate are calculated. Peak shearing rates near the outboard edge are in the 10-100 krad/s range.

  11. The Effects of Thermonuclear Reaction Rate Variations on 26Al Production in Massive Stars: A Sensitivity Study (United States)

    Iliadis, Christian; Champagne, Art; Chieffi, Alessandro; Limongi, Marco


    We investigate the effects of thermonuclear reaction rate variations on 26Al production in massive stars. The dominant production sites in such events were recently investigated by using stellar model calculations: explosive neon-carbon burning, convective shell carbon burning, and convective core hydrogen burning. Post-processing nucleosynthesis calculations are performed for each of these sites by adopting temperature-density-time profiles from recent stellar evolution models. For each profile, we individually multiplied the rates of all relevant reactions by factors of 10, 2, 0.5, and 0.1, and analyzed the resulting abundance changes of 26Al. In total, we performed ≈900 nuclear reaction network calculations. Our simulations are based on a next-generation nuclear physics library, called STARLIB, which contains a recent evaluation of Monte Carlo reaction rates. Particular attention is paid to quantifying the rate uncertainties of those reactions that most sensitively influence 26Al production. For stellar modelers our results indicate to what degree predictions of 26Al nucleosynthesis depend on currently uncertain nuclear physics input, while for nuclear experimentalists our results represent a guide for future measurements. We also investigate equilibration effects of 26Al. In all previous massive star investigations, either a single species or two species of 26Al were taken into account, depending on whether thermal equilibrium was achieved or not. These are two extreme assumptions, and in a hot stellar plasma the ground and isomeric states may communicate via γ-ray transitions involving higher-lying 26Al levels. We tabulate the results of our reaction rate sensitivity study for each of the three distinct massive star sites referred to above. It is found that several current reaction rate uncertainties influence the production of 26Al. Particularly important reactions are 26Al(n,p)26Mg, 25Mg(α,n)28Si, 24Mg(n,γ)25Mg, and 23Na(α,p)26Mg. These reactions

  12. Thermonuclear device and operation method therefor

    Energy Technology Data Exchange (ETDEWEB)

    Kobayashi, Noriyuki


    A flow rate of cooling medium for cooling heat generation portions such as of a blanket, a first wall, a divertor plate and a vacuum vessel during stoppage of plasma is reduced lower than that during plasma discharge thereby maintaining a temperature of heat generation portion to a predetermined level irrespective of discharge or stoppage of plasmas. Alternatively, a cooling medium supply/discharge system is divided for each of equipments, and a flow rate control valve is disposed on every cooling medium supply/discharge system for controlling the flow rate of the cooling medium thereby maintaining each of the equipments having different heat generation amount at a predetermined temperature. Further, at least two intermittently operating device main bodies are disposed, and the heat output waveform of each of the device main bodies is made trapezoidal, and the devices are operated alternately so that a rising portion of one of the heat output waveforms and a falling portion of the other of the heat output waveforms are overlaid with each other to make the heat output on the overlaid portion identical with that of the output of a single device thereby making the total heat output constant. Then, repeating thermal stresses can be prevented to suppress degradation of the strength thereby enabling to realize highly reliable intermittent operation of the thermonuclear reactor. (N.H.)

  13. Measurement Development in Reflective Supervision: History, Methods, and Next Steps (United States)

    Tomlin, Angela M.; Heller, Sherryl Scott


    This issue of the "ZERO TO THREE" journal provides a snapshot of the current state of measurement of reflective supervision within the infant-family field. In this article, the authors introduce the issue by providing a brief history of the development of reflective supervision in the field of infant mental health, with a specific focus…

  14. The NEXT experiment

    Energy Technology Data Exchange (ETDEWEB)

    DIaz, J; Yahlali, N; Ball, M; Carcel, S; Cervera, A; Gil, A [Instituto de Fisica Corpuscular (Centro mixto UV-CSIC), Apdo. de Correos 22085, E-46071 Valencia (Spain) (Spain); Barata, J A S; Borges, F I G M; Conde, C A N; Dias, T H V T; Fernandes, L M P; Freitas, E D C [Universidade de Coimbra (Portugal); Calvo, E [Instituto de Fisica de Altas EnergIas, IFAE, Barcelona (Spain); Carmona, J M; Cebrian, S; Dafni, T; Galan, J [U. Zaragoza (Spain); Cid, X [Universidade de Santiago de Compostela (Spain); Ferrer-Ribas, E [CEA, IRFU, Saclay (France); Gil, I, E-mail: jose.diaz@uv.e [CIEMAT (Spain)


    Neutrinoless double beta decay measurements are the most promising experiments both to reveal the Majorana nature of the neutrino and to set a value for its mass. The NEXT project propose to build a High pressure Xenon TPC in the Canfranc Underground Laboratory (Huesca, Spain) to measure double-beta decay of {sup 136}Xe, both normal and neutrinoless, with a source mass of 100 kg of enriched xenon.

  15. Carbon Capture and Storage: Progress and Next Steps

    Energy Technology Data Exchange (ETDEWEB)



    Two years after the G8 leaders commitment to the broad deployment of carbon capture and storage (CCS) by 2020, significant progress has been made towards commercialisation of CCS technologies. Yet the 2008 Hokkaido G8 recommendation to launch 20 large-scale CCS demonstration projects by 2010 remains a challenge and will require that governments and industry accelerate the pace toward achieving this critical goal. This is one of the main findings of a new report by the International Energy Agency (IEA), the Carbon Sequestration Leadership Forum (CSLF), and the Global CCS Institute, to be presented to G8 leaders at their June Summit in Muskoka, Canada.

  16. Next step in policy transitions: Diffusion of pilot projects

    CSIR Research Space (South Africa)

    Vreugdenhil, H


    Full Text Available of half-wild naturally present grazers such as horses. In Beuningen, CFR has first been applied in a pilot project within the framework of the EU-Interreg IIIb project ?Freude am Fluss? (Peters et al. 2006). The pilot is undertaken in the policy...

  17. Just Diagnosed: Next Steps After Testing Positive for HIV (United States)

    ... and reduces the amount of HIV in the body. ART can’t cure HIV, but it helps people ... damaged immune system makes it hard for the body to fight off infections. ... the better. ART is recommended as soon as possible for everyone ...

  18. SSWR Water Systems Project 2: Next Steps – Technology Advances (United States)

    EPA is responsible for protecting America’s water resources under the Clean Water Act (CWA) and for ensuring that the Nation’s drinking water is safe under the Safe Drinking Water Act (SDWA). Further, it is the responsibility of EPA to conduct research and analyses t...

  19. The Next Step in Deployment of Computer Based Procedures For Field Workers: Insights And Results From Field Evaluations at Nuclear Power Plants

    Energy Technology Data Exchange (ETDEWEB)

    Oxstrand, Johanna; Le Blanc, Katya L.; Bly, Aaron


    The paper-based procedures currently used for nearly all activities in the commercial nuclear power industry have a long history of ensuring safe operation of the plants. However, there is potential to greatly increase efficiency and safety by improving how the human operator interacts with the procedures. One way to achieve these improvements is through the use of computer-based procedures (CBPs). A CBP system offers a vast variety of improvements, such as context driven job aids, integrated human performance tools (e.g., placekeeping, correct component verification, etc.), and dynamic step presentation. The latter means that the CBP system could only display relevant steps based on operating mode, plant status, and the task at hand. A dynamic presentation of the procedure (also known as context-sensitive procedures) will guide the operator down the path of relevant steps based on the current conditions. This feature will reduce the operator’s workload and inherently reduce the risk of incorrectly marking a step as not applicable and the risk of incorrectly performing a step that should be marked as not applicable. The research team at the Idaho National Laboratory has developed a prototype CBP system for field workers, which has been evaluated from a human factors and usability perspective in four laboratory studies. Based on the results from each study revisions were made to the CBP system. However, a crucial step to get the end users' (e.g., auxiliary operators, maintenance technicians, etc.) acceptance is to put the system in their hands and let them use it as a part of their everyday work activities. In the spring 2014 the first field evaluation of the INL CBP system was conducted at a nuclear power plant. Auxiliary operators conduct a functional test of one out of three backup air compressors each week. During the field evaluation activity, one auxiliary operator conducted the test with the paper-based procedure while a second auxiliary operator

  20. TMS field modelling-status and next steps

    DEFF Research Database (Denmark)

    Thielscher, Axel


    In the recent years, an increasing number of studies used geometrically accurate head models and finite element (FEM) or finite difference methods (FDM) to estimate the electric field induced by non-invasive neurostimulation techniques such as transcranial magnetic stimulation (TMS) or transcranial...... ( that allows for the automatic creation of accurate head models from structural and diffusion-weighted magnetic resonance images (MRI) (Windhoff et al., 2011). This enables us to perform field calculations for multiple subjects, as required in neuroscientific studies. We substantially...... will start by summarizing the key findings on how the individual brain anatomy shapes the electric field induced by TMS (Thielscher et al., 2011; Opitz, 2011). The putative link between the modeling results and basic physiological TMS effects is highlighted. I will then introduce the novel features of Sim...

  1. Next Step Toward Widespread Residential Deep Energy Retrofits

    Energy Technology Data Exchange (ETDEWEB)

    McIlvaine, J.; Saunders, S.; Bordelon, E.; Baden, S.; Elam, L.; Martin, E.


    The complexity of deep energy retrofits warrants additional training to successfully manage multiple improvements that will change whole house air, heat, and moisture flow dynamics. The home performance contracting industry has responded to these challenges by aggregating skilled labor for assessment of and implementation under one umbrella. Two emerging business models are profiled that seek to resolve many of the challenges, weaknesses, opportunities, and threats described for the conventional business models.

  2. Next Steps for Transforming Education at National Defense University (United States)


    could and should be a humanist approach that emphasizes the importance of meeting the student’s full range of needs: emotional, spiritual, physical...The New Censor- ship: Institutional Review Boards,” Supreme Court Review 271 (2004). 15 Tom Bartlett, “Social- Psychology Researchers Are Very

  3. Combined Space and Water Heating: Next Steps to Improved Performance

    Energy Technology Data Exchange (ETDEWEB)

    Schoenbauer, B. [NorthernSTAR Building America Partnership, Minneapolis, MN (United States); Bohac, D. [NorthernSTAR Building America Partnership, Minneapolis, MN (United States); Huelman, P. [NorthernSTAR Building America Partnership, Minneapolis, MN (United States)


    A combined space- and water-heating (combi) system uses a high-efficiency direct-vent burner that eliminates safety issues associated with natural draft appliances. Past research with these systems shows that using condensing water heaters or boilers with hydronic air handling units can provide both space and water heating with efficiencies of 90% or higher. Improved controls have the potential to reduce complexity and improve upon the measured performance. This project demonstrates that controls can significantly benefit these first-generation systems. Laboratory tests and daily load/performance models showed that the set point temperature reset control produced a 2.1%–4.3% (20–40 therms/year) savings for storage and hybrid water heater combi systems operated in moderate-load homes. The full modulation control showed additional savings over set point control (in high-load homes almost doubling the savings: 4%–5% over the no-control case). At the time of installation the reset control can be implemented for $200–$400, which would provide paybacks of 6–25 years for low-load houses and 3–15 years for high-load houses. Full modulation implementation costs would be similar to the outdoor reset and would provide paybacks of 5-½–20 years for low-load houses and 2-½–10 years for high-load houses.

  4. Precision medicine in pediatric oncology: Lessons learned and next steps. (United States)

    Mody, Rajen J; Prensner, John R; Everett, Jessica; Parsons, D Williams; Chinnaiyan, Arul M


    The maturation of genomic technologies has enabled new discoveries in disease pathogenesis as well as new approaches to patient care. In pediatric oncology, patients may now receive individualized genomic analysis to identify molecular aberrations of relevance for diagnosis and/or treatment. In this context, several recent clinical studies have begun to explore the feasibility and utility of genomics-driven precision medicine. Here, we review the major developments in this field, discuss current limitations, and explore aspects of the clinical implementation of precision medicine, which lack consensus. Lastly, we discuss ongoing scientific efforts in this arena, which may yield future clinical applications. © 2016 Wiley Periodicals, Inc.

  5. Strategic Forum. Number 283, December 2013. Next Steps in Syria (United States)


    4604579067382861808984.html>. 4 Iranian scholars, interview by author, February and September 2012. 5 Cited by Deutsche Presse-Agentur, September 16, 2013...components as well. 11 Anne Barnard, “In Syrian Victory, Hezbollah Risks Broader Fight,” The New York Times, June 6, 2013, A1; Karl Vick, “The Fall

  6. Emergency Medicine Resident Rotations Abroad: Current Status and Next Steps

    Directory of Open Access Journals (Sweden)

    Stephen C. Morris, MD, MPH


    Full Text Available Introduction: International rotations for residents are increasingly popular, but there is a dearth of evidence to demonstrate that these rotations are safe and that residents have appropriate training and support to conduct them. Methods: A survey was sent to all U.S. emergency medicine (EM residencies with publicly available e-mail addresses. The survey documents and examines the training and support that emergency medicine residents are offered for international rotations and the frequency of adverse safety events. Results: 72.5% of program director responded that their residents are participating in rotations abroad. However, only 15.4% of programs reported offering training specific to working abroad. The results point to an increased need for specific training and insurance coverage. Conclusion: Oversight of international rotations should be improved to guarantee safety and education benefit.

  7. Combined Space and Water Heating: Next Steps to Improved Performance

    Energy Technology Data Exchange (ETDEWEB)

    Schoenbauer, B. [NorthernSTAR Building America Partnership, Minneapolis, MN (United States); Bohac, D. [NorthernSTAR Building America Partnership, Minneapolis, MN (United States); Huelman, P. [NorthernSTAR Building America Partnership, Minneapolis, MN (United States)


    A combined space- and water-heating (combi) system uses a high-efficiency direct-vent burner that eliminates safety issues associated with natural draft appliances. Past research with these systems shows that using condensing water heaters or boilers with hydronic air handling units can provide both space and water heating with efficiencies of 90% or higher. Improved controls have the potential to reduce complexity and improve upon the measured performance. This project demonstrates that controls can significantly benefit these first-generation systems. Laboratory tests and daily load/performance models showed that the set point temperature reset control produced a 2.1%-4.3% (20-40 therms/year) savings for storage and hybrid water heater combi systems operated in moderate-load homes.

  8. Charting the way forward to better quality health care: how do we get there and what are the next steps? Recommendations from the Salzburg Global Seminar on making health care better in low- and middle-income economies. (United States)

    Massoud, M Rashad; Mensah-Abrampah, Nana; Sax, Sylvia; Leatherman, Sheila; Agins, Bruce; Barker, Pierre; Kelley, Edward; Heiby, James R; Lotherington, John


    In April 2012, the Salzburg Global Seminar (SGS) brought together 58 health leaders from 33 countries to review experiences in improving the quality and safety of health-care services in low- and middle-income countries, synthesize lessons learned from those experiences, discuss challenges and opportunities and recommend next steps to stimulate improvement in such countries. This work summarizes the seminar's key results, expressed as five shared challenges and five lessons learned. The seminar featured a series of interactive sessions with an all-teach, all-learn approach. Session topics were: introduction to the seminar, journey to date, challenges that lie ahead, overcoming the issues of confusion, sustaining execution, strengthening leadership and policy, the role of quality improvement in health systems strengthening and setting the agenda for learning and next steps. Key lessons from the SGS include reducing terminology and methodology confusion, strengthening the learning agenda, embracing improvement science as a means for strengthening health-care systems, developing leadership in improving health care and ensuring that health-care systems focus on patients and communities. A call to action was developed by SGS participants and presented at the 65th World Health Assembly in Geneva. There is an inarguable need to move improvement in health care to a new level to attain and exceed the Millennium Development Goals. The challenges can be overcome through concerted action of key stakeholders and the application of scientifically grounded management methods to enable the reliable implementation of high-impact interventions for every patient every time needed.

  9. One Step Biomass Gas Reforming-Shift Separation Membrane Reactor

    Energy Technology Data Exchange (ETDEWEB)

    Roberts, Michael J. [Gas Technology Institute; Souleimanova, Razima [Gas Technology Institute


    GTI developed a plan where efforts were concentrated in 4 major areas: membrane material development, membrane module development, membrane process development, and membrane gasifier scale-up. GTI assembled a team of researchers to work in each area. Task 1.1 Ceramic Membrane Synthesis and Testing was conducted by Arizona State University (ASU), Task 1.2 Metallic Membrane Synthesis and Testing was conducted by the U.S. National Energy Technology Laboratory (NETL), Task 1.3 was conducted by SCHOTT, and GTI was to test all membranes that showed potential. The initial focus of the project was concentrated on membrane material development. Metallic and glass-based membranes were identified as hydrogen selective membranes under the conditions of the biomass gasification, temperatures above 700C and pressures up to 30 atmospheres. Membranes were synthesized by arc-rolling for metallic type membranes and incorporating Pd into a glass matrix for glass membranes. Testing for hydrogen permeability properties were completed and the effects of hydrogen sulfide and carbon monoxide were investigated for perspective membranes. The initial candidate membrane of Pd80Cu20 chosen in 2008 was selected for preliminary reactor design and cost estimates. Although the H2A analysis results indicated a $1.96 cost per gge H2 based on a 5A (micron) thick PdCu membrane, there was not long-term operation at the required flux to satisfy the go/no go decision. Since the future PSA case yielded a $2.00/gge H2, DOE decided that there was insufficient savings compared with the already proven PSA technology to further pursue the membrane reactor design. All ceramic membranes synthesized by ASU during the project showed low hydrogen flux as compared with metallic membranes. The best ceramic membrane showed hydrogen permeation flux of 0.03 SCFH/ft2 at the required process conditions while the metallic membrane, Pd80Cu20 showed a flux of 47.2 SCFH/ft2 (3 orders of magnitude difference). Results from

  10. Review of the status of low power research reactors and considerations for its development

    Energy Technology Data Exchange (ETDEWEB)

    Lim, In Cheol; Wu, Sang Ik; Lee, Byung Chul; Ha, Jae Joo [KAERI, Daejeon (Korea, Republic of)


    At present, 232 research reactors in the world are in operation and two thirds of them have a power less than 1 MW. Many countries have used research reactors as the tools for educating and training students or engineers and for scientific service such as neutron activation analysis. As the introduction of a research reactor is considered a stepping stone for a nuclear power development program, many newcomers are considering having a low power research reactor. The IAEA has continued to provide forums for the exchange of information and experiences regarding low power research reactors. Considering these, the Agency is recently working on the preparation of a guide for the preparation of technical specification possibly for a member state to use when wanting to purchase a low power research reactor. In addition, ANS has stated that special consideration should be given to the continued national support to maintain and expand research and test reactor programs and to the efforts in identifying and addressing the future needs by working toward the development and deployment of next generation nuclear research and training facilities. Thus, more interest will be given to low power research reactors and its role as a facility for education and training. Considering these, the status of low power research reactors was reviewed, and some aspects to be considered in developing a low power research reactor were studied.

  11. Hacking the next generation

    CERN Document Server

    Dhanjani, Nitesh; Hardin, Brett


    With the advent of rich Internet applications, the explosion of social media, and the increased use of powerful cloud computing infrastructures, a new generation of attackers has added cunning new techniques to its arsenal. For anyone involved in defending an application or a network of systems, Hacking: The Next Generation is one of the few books to identify a variety of emerging attack vectors. You'll not only find valuable information on new hacks that attempt to exploit technical flaws, you'll also learn how attackers take advantage of individuals via social networking sites, and abuse

  12. Development of a Ground Test and Analysis Protocol to Support NASA's NextSTEP Phase 2 Habitation Concepts (United States)

    Beaton, Kara H.; Chappell, Steven P.; Bekdash, Omar S.; Gernhardt, Michael L.


    The NASA Next Space Technologies for Exploration Partnerships (NextSTEP) program is a public-private partnership model that seeks commercial development of deep space exploration capabilities to support extensive human spaceflight missions around and beyond cislunar space. NASA first issued the Phase 1 NextSTEP Broad Agency Announcement to U.S. industries in 2014, which called for innovative cislunar habitation concepts that leveraged commercialization plans for low Earth orbit. These habitats will be part of the Deep Space Gateway (DSG), the cislunar space station planned by NASA for construction in the 2020s. In 2016, Phase 2 of the NextSTEP program selected five commercial partners to develop ground prototypes. A team of NASA research engineers and subject matter experts have been tasked with developing the ground test protocol that will serve as the primary means by which these Phase 2 prototype habitats will be evaluated. Since 2008, this core test team has successfully conducted multiple spaceflight analog mission evaluations utilizing a consistent set of operational products, tools, methods, and metrics to enable the iterative development, testing, analysis, and validation of evolving exploration architectures, operations concepts, and vehicle designs. The purpose of implementing a similar evaluation process for the NextSTEP Phase 2 Habitation Concepts is to consistently evaluate the different commercial partner ground prototypes to provide data-driven, actionable recommendations for Phase 3.

  13. One-step synthesis of pyridines and dihydropyridines in a continuous flow microwave reactor. (United States)

    Bagley, Mark C; Fusillo, Vincenzo; Jenkins, Robert L; Lubinu, M Caterina; Mason, Christopher


    The Bohlmann-Rahtz pyridine synthesis and the Hantzsch dihydropyridine synthesis can be carried out in a microwave flow reactor or using a conductive heating flow platform for the continuous processing of material. In the Bohlmann-Rahtz reaction, the use of a Brønsted acid catalyst allows Michael addition and cyclodehydration to be carried out in a single step without isolation of intermediates to give the corresponding trisubstituted pyridine as a single regioisomer in good yield. Furthermore, 3-substituted propargyl aldehydes undergo Hantzsch dihydropyridine synthesis in preference to Bohlmann-Rahtz reaction in a very high yielding process that is readily transferred to continuous flow processing.

  14. Results from MARBLE DT Experiments on the National Ignition Facility: Implosion of Foam-Filled Capsules for Studying Thermonuclear Burn in the Presence of Heterogeneous Mix (United States)

    Murphy, T. J.; Douglas, M. R.; Cardenas, T.; Cooley, J. H.; Gunderson, M. A.; Haines, B. M.; Hamilton, C. E.; Kim, Y.; Lee, M. N.; Oertel, J. A.; Olson, R. E.; Randolph, R. B.; Shah, R. C.; Smidt, J. M.


    The MARBLE campaign on NIF investigates the effect of heterogeneous mix on thermonuclear burn for comparison to a probability distribution function (PDF) burn model. MARBLE utilizes plastic capsules filled with deuterated plastic foam and tritium gas. The ratio of DT to DD neutron yield is indicative of the degree to which the foam and the gas atomically mix. Platform development experiments have been performed to understand the behavior of the foam and of the gas separately using two types of capsule. The first experiments using deuterated foam and tritium gas have been performed. Results of these experiments, and the implications for our understanding of thermonuclear burn in heterogeneously mixed separated reactant experiments will be discussed. This work is supported by US DOE/NNSA, performed at LANL, operated by LANS LLC under contract DE-AC52-06NA25396.

  15. When Will We Ever Learn? The After Action Review, Lessons Learned and the Next Steps in Training and Educating the Homeland Security Enterprise for the 21st Century (United States)


    the past is not exclusive to the U.S. Army or the U.S. homeland security enterprise. A precursor to the AAR was established at Boeing in 1969 when it...instituted Project Homework. This initiative was an attempt to compare the problem-ridden 737 and 747 plane programs with the 707 and 727 programs...techniques, and procedures necessary to effectively integrate KM into the operations of brigades, divisions, and corps.”77 This field manual represents the

  16. Simulating Thermonuclear Runaway in Novae (United States)

    Dursi, L. J.; Truran, J.; Zingale, M.; Calder, A. C.; Fryxell, B.; Olson, K.; Ricker, P.; Rosner, R.; Timmes, F. X.; Tufo, H. M.; MacNeice, P.


    A nova is a thought to result from a partially degenerate thermonuclear runaway on the surface of a white dwarf. Material from the underlying white dwarf must be dredged up into the atmosphere in order to produce an explosion with the observed energies; the carbon and oxygen serve as catalysts for the hydrogen burning, allowing the much more temperature-sensitive CNO burning to occur. In order to understand this dredge-up problem, we are running two different types of simulations. The first are large-scale simulations with the FLASH code (Fryxell et al., 2000), using a one-dimensional set of initial conditions of a nova about to undergo runaway created by Ami Glasner. These initial conditions have been used in previous multidimensional simulations (Glasner et al. 1997; Kercek et al. 1998), but these simulations have given widely different results because of different mixing behaviors in the two codes. Our set of simulations will shed some light on this discrepancy; since our code has adaptive mesh refinement (MacNeice et al., 2000), we can afford to highly refine the region of the star where the mixing occurs, without the cost of highly refining the entire region. Because these large-scale computations are extremely compute-intensive, they are not appropriate for broad exploration of initial conditions. To do this, we use a One-Dimensional Turbulence (ODT) model which has been used in astrophysical models previously (Niemeyer & Kerstein, 1997). This allows us to use ODT simulations of the nova as experiments to guide us to interesting regimes to study further with multidimensional FLASH code simulations. This work was supported in part by the Department of Energy Grant No. B341495 to the Center for Astrophysical Thermonuclear Flashes at the University of Chicago under the ASCI Strategic Alliances Program and by NASA/Goddard Space Flight Center

  17. Usability of an internet-based platform (Next.Step) for adolescent weight management. (United States)

    Sousa, Pedro; Fonseca, Helena; Gaspar, Pedro; Gaspar, Filomena


    The current study evaluates the usability perception of an e-therapeutic platform (supported by electronic processes and communication), aiming to promote the behavior change and to improve the adolescent health status through increased and interactive contact between the adolescent and the clinical staff. This was a correlational study with a sample of 48 adolescents (12-18 years) who attended a Pediatric Obesity Clinic between January and August of 2012. Participants were invited to access, during 24 weeks, the e-therapeutic multidisciplinary platform (Next.Step) in addition to the standard treatment program. A usability questionnaire was administered and the platform performance and utilization indicators were analyzed. The users' perception of satisfaction, efficiency, and effectiveness regarding the Next.Step platform was clearly positive. However, only 54.17% of the enrolled adolescents accessed the platform, with a mean task-completion rate of 14.55% (SD=18.853). The higher the number of the platform consulted resources, the greater the tendency to enjoy the platform, to consider it exciting and quick, to consider that the time spent in it was useful, to consider the access to information easy, and to login easier. Post-intervention assessment revealed a significant reduction in anthropometric and behavioral variables, including body mass index z-score, waist circumference percentile, hip circumference, and weekly screen time. These results highlight the importance of information and communication technologies in the health information access and the healthcare provision. Despite the limited adherence rate, platform users expressed a positive overall perception of its usability and presented a positive anthropometric and behavioral progress. Copyright © 2014 Sociedade Brasileira de Pediatria. Published by Elsevier Editora Ltda. All rights reserved.

  18. Usability of an internet-based platform (Next.Step for adolescent weight management

    Directory of Open Access Journals (Sweden)

    Pedro Sousa


    Full Text Available OBJECTIVE: The current study evaluates the usability perception of an e-therapeutic platform (supported by electronic processes and communication, aiming to promote the behavior change and to improve the adolescent health status through increased and interactive contact between the adolescent and the clinical staff. METHODS: This was a correlational study with a sample of 48 adolescents (12-18 years who attended a Pediatric Obesity Clinic between January and August of 2012. Participants were invited to access, during 24 weeks, the e-therapeutic multidisciplinary platform (Next.Step in addition to the standard treatment program. A usability questionnaire was administered and the platform performance and utilization indicators were analyzed. RESULTS: The users' perception of satisfaction, efficiency, and effectiveness regarding the Next.Step platform was clearly positive. However, only 54.17% of the enrolled adolescents accessed the platform, with a mean task-completion rate of 14.55% (SD = 18.853. The higher the number of the platform consulted resources, the greater the tendency to enjoy the platform, to consider it exciting and quick, to consider that the time spent in it was useful, to consider the access to information easy, and to login easier. Post-intervention assessment revealed a significant reduction in anthropometric and behavioral variables, including body mass index z-score, waist circumference percentile, hip circumference, and weekly screen time. CONCLUSION: These results highlight the importance of information and communication technologies in the health information access and the healthcare provision. Despite the limited adherence rate, platform users expressed a positive overall perception of its usability and presented a positive anthropometric and behavioral progress.

  19. Novel cancer immunotherapy agents with survival benefit: recent successes and next steps (United States)

    Sharma, Padmanee; Wagner, Klaus; Wolchok, Jedd D.; Allison, James P.


    The US Food and Drug Administration (FDA) recently approved two novel immunotherapy agents, sipuleucel-T and ipilimumab, which showed a survival benefit for patients with metastatic prostate cancer and melanoma, respectively. The mechanisms by which these agents provide clinical benefit are not completely understood. However, knowledge of these mechanisms will be crucial for probing human immune responses and tumour biology in order to understand what distinguishes responders from non-responders. The following next steps are necessary: first, the development of immune-monitoring strategies for the identification of relevant biomarkers; second, the establishment of guidelines for the assessment of clinical end points; and third, the evaluation of combination therapy strategies to improve clinical benefit. PMID:22020206

  20. Progress in palliative care in Israel: comparative mapping and next steps. (United States)

    Bentur, Netta; Emanuel, Linda L; Cherney, Nathan


    Palliative care was established rapidly in some countries, while in other countries its establishment has taken a different trajectory. This paper identifies core steps in developing a medical specialty and examines those taken by Israel as compared with the US and England for palliative care. It considers the next steps Israel may take.Palliative care aims to provide quality of life for those with serious illnesses by attending to the illness-prompted physical, mental, social, and spiritual needs of patients and their families. It has ancient roots in medicine; its modern iteration began against the backdrop of new cures and life-sustaining technology which challenged conceptions of how to respect the sanctity of life.The first modern hospice was created by Saunders; it provided proof that palliative care works, and this has occurred in Israel as well (the first step). Another key step is usually skills development among clinicians; in Israel, few education and training opportunities exist so far. Specialty recognition also has not yet occurred in Israel. Service development remains limited and a major shortage of services exists, compared to the US. Research capacity in Israel is also limited. Policy to develop and sustain palliative care in Israel is underway; in 2009, the Ministry of Health established policy for implementing palliative care. However, it still lacks a financially viable infrastructure.We conclude that palliative care in Israel is emerging but has far to go. Adequate resource allocation, educational guidelines, credentialed manpower and specialty leadership are the key factors that palliative care development in Israel needs.

  1. Progress in palliative care in Israel: comparative mapping and next steps

    Directory of Open Access Journals (Sweden)

    Bentur Netta


    Full Text Available Abstract Palliative care was established rapidly in some countries, while in other countries its establishment has taken a different trajectory. This paper identifies core steps in developing a medical specialty and examines those taken by Israel as compared with the US and England for palliative care. It considers the next steps Israel may take. Palliative care aims to provide quality of life for those with serious illnesses by attending to the illness-prompted physical, mental, social, and spiritual needs of patients and their families. It has ancient roots in medicine; its modern iteration began against the backdrop of new cures and life-sustaining technology which challenged conceptions of how to respect the sanctity of life. The first modern hospice was created by Saunders; it provided proof that palliative care works, and this has occurred in Israel as well (the first step. Another key step is usually skills development among clinicians; in Israel, few education and training opportunities exist so far. Specialty recognition also has not yet occurred in Israel. Service development remains limited and a major shortage of services exists, compared to the US. Research capacity in Israel is also limited. Policy to develop and sustain palliative care in Israel is underway; in 2009, the Ministry of Health established policy for implementing palliative care. However, it still lacks a financially viable infrastructure. We conclude that palliative care in Israel is emerging but has far to go. Adequate resource allocation, educational guidelines, credentialed manpower and specialty leadership are the key factors that palliative care development in Israel needs.

  2. What is the most relevant standard of success in assisted reproduction? The next step to improving outcomes of IVF : consider the whole treatment

    NARCIS (Netherlands)

    Heijnen, EMEW; Macklon, NS; Fauser, BCJM

    Changing the way in which successful IVF treatment is defined offers a tool to improve efficacy while reducing costs and complications of treatment. Crucial to this paradigm shift is the move away from considering outcomes in terms of the single IVF cycle, and towards the started IVF treatment as a

  3. Towards the next chapter

    CERN Multimedia


    In the late 1970s, while the CERN community was busy preparing the SPS to operate as a collider and planning for LEP, people also had their eyes on the next chapter in the unfolding story of CERN.   That the LEP tunnel should be built with a future hadron collider in mind was a given by the end of the decade. But there had also been proposals to build large proton storage rings, or re-equip the ISR with superconducting magnets. Some people had suggested building an electron-proton collider at CERN, and there were ambitious plans looking far into the future at a possible Very Big Accelerator to be built somewhere in the world, which went by its acronym VBA. For the field of particle physics, with its very long lead times, this is part of the normal cycle, and while most of those options never came to fruition, this process did pave the way for the LHC. Today, with the LHC programme underway, the time has come for CERN to start seriously considering the options for its post-LHC future. Perhaps ...

  4. The way to collisions, step by step

    CERN Multimedia


    While the LHC sectors cool down and reach the cryogenic operating temperature, spirits are warming up as we all eagerly await the first collisions. No reason to hurry, though. Making particles collide involves the complex manoeuvring of thousands of delicate components. The experts will make it happen using a step-by-step approach.

  5. Neutron Stars and Thermonuclear X-ray Bursts (United States)

    Bhattacharyya, Sudip


    Studies of thermonuclear X-ray bursts can be very useful to constrain the spin rate, mass and radius of a neutron star approaching EOS model of high density cold matter in the neutron star cores. +k Extensive observation and analysis of the data from the rising portions of the bursts - modeling of burst oscillations and thermonuclear flame spreading. +k Theoretical study of thermonuclear flame spreading on the rapidly spinning neutron stars should be done considering all the main physical effects (including magnetic field, nuclear energy generation, Coriolis effect, strong gravity, etc.).

  6. Understanding Neutron Stars using Thermonuclear X-ray Bursts (United States)

    Bhattacharyya, S.


    Studies of thermonuclear X-ray bursts can be very useful to constrain the spin rate, mass and radius of a neutron star = EOS model of high density cold matter in the neutron star cores. Extensive observation and analysis of the data from the rising portions of the bursts = modeling of burst oscillations and thermonuclear flame spreading. Theoretical study of thermonuclear flame spreading on the rapidly spinning neutron stars should be done considering all the main physical effects (including magnetic field, nuclear energy generation, Coriolis effect, strong gravity, etc.).

  7. The Next Generation EMR. (United States)

    Keshavjee, Karim; Mirza, Kashif; Martin, Ken


    Electronic medical/health record (EMR) usage in North America has increased significantly in the last half decade. But there is widespread dissatisfaction with the technologies that are currently available in the market place. Our hypothesis is that EMR vendors and the market place alone cannot solve the issue of poor technology. We propose an architecture for the next generation of electronic records that solves current concerns of end users and addresses the needs of additional stakeholders, including health system funders, patients, researchers and guideline implementers. By including additional stakeholders, we believe that additional resources, competencies and functionality can be unleashed to solve the larger problems of the current generation of EMRs. The architecture also addresses future requirements that are likely to arise from technological developments such as mobile apps and PHRs and from innovations in medicine, including genomics, artificial intelligence and personalized medicine. The paper makes a call to action for informatics researchers to play a greater role in R&D on EMRs.

  8. Gamma-ray emission spectrum from thermonuclear fusion reactions without intrinsic broadening

    DEFF Research Database (Denmark)

    Nocente, M.; Källne, J.; Salewski, Mirko


    First principle calculations of the gamma-ray energy spectrum arising from thermonuclear reactions without intrinsic broadening in fusion plasmas are presented, extending the theoretical framework needed to interpret measurements up to the accuracy level enabled by modern high resolution instrume......First principle calculations of the gamma-ray energy spectrum arising from thermonuclear reactions without intrinsic broadening in fusion plasmas are presented, extending the theoretical framework needed to interpret measurements up to the accuracy level enabled by modern high resolution...... information that can be extracted from the gamma-ray emission spectrum of fusion reactions without intrinsic broadening and are of relevance for applications to high performance plasmas of present and next generation devices....

  9. If you want to get a job done, you need the right tools: Next steps for the UN Convention to Combat Desertification

    Energy Technology Data Exchange (ETDEWEB)

    Toulmin, Camilla


    Is the UN Convention to Combat Desertification (CCD) bringing the right set of tools to the task of addressing the problems facing dryland peoples around the world? Many of the challenges that face the drylands are not addressed by the current CCD toolkit. Three principal areas where attention should now be focused are working closely with the Convention on Climate Change (UNFCC) to identify strategies to help the drylands adapt to climate change, engaging with the changing aid architecture, and securing rights to land and natural resources for dryland populations.

  10. The ARIES tokamak reactor study

    Energy Technology Data Exchange (ETDEWEB)


    The ARIES study is a community effort to develop several visions of tokamaks as fusion power reactors. The aims are to determine the potential economics, safety, and environmental features of a range of possible tokamak reactors, and to identify physics and technology areas with the highest leverage for achieving the best tokamak reactor. Three ARIES visions are planned, each having a different degree of extrapolation from the present data base in physics and technology. The ARIES-I design assumes a minimum extrapolation from current tokamak physics (e.g., 1st stability) and incorporates technological advances that can be available in the next 20 to 30 years. ARIES-II is a DT-burning tokamak which would operate at a higher beta in the 2nd MHD stability regime. It employs both potential advances in the physics and expected advances in technology and engineering. ARIES-II will examine the potential of the tokamak and the D{sup 3}He fuel cycle. This report is a collection of 14 papers on the results of the ARIES study which were presented at the IEEE 13th Symposium on Fusion Engineering (October 2-6, 1989, Knoxville, TN). This collection describes the ARIES research effort, with emphasis on the ARIES-I design, summarizing the major results, the key technical issues, and the central conclusions.

  11. Hybrid fusion–fission reactor with a thorium blanket: Its potential in the fuel cycle of nuclear reactors

    Energy Technology Data Exchange (ETDEWEB)

    Shmelev, A. N., E-mail:; Kulikov, G. G., E-mail:; Kurnaev, V. A., E-mail:; Salahutdinov, G. H., E-mail:; Kulikov, E. G., E-mail:; Apse, V. A., E-mail: [National Research Nuclear University MEPhI (Moscow Engineering Physics Institute) (Russian Federation)


    Discussions are currently going on as to whether it is suitable to employ thorium in the nuclear fuel cycle. This work demonstrates that the {sup 231}Pa–{sup 232}U–{sup 233}U–Th composition to be produced in the thorium blanket of a hybrid thermonuclear reactor (HTR) as a fuel for light-water reactors opens up the possibility of achieving high, up to 30% of heavy metals (HM), or even ultrahigh fuel burnup. This is because the above fuel composition is able to stabilize its neutron-multiplying properties in the process of high fuel burnup. In addition, it allows the nuclear fuel cycle (NFC) to be better protected against unauthorized proliferation of fissile materials owing to an unprecedentedly large fraction of {sup 232}U (several percent!) in the uranium bred from the Th blanket, which will substantially hamper the use of fissile materials in a closed NFC for purposes other than power production.

  12. Estimating heterotrophic respiration at large scales: Challenges, approaches, and next steps (United States)

    Bond-Lamberty, Ben; Epron, Daniel; Harden, Jennifer W.; Harmon, Mark E.; Hoffman, Forrest; Kumar, Jitendra; McGuire, Anthony David; Vargas, Rodrigo


    Heterotrophic respiration (HR), the aerobic and anaerobic processes mineralizing organic matter, is a key carbon flux but one impossible to measure at scales significantly larger than small experimental plots. This impedes our ability to understand carbon and nutrient cycles, benchmark models, or reliably upscale point measurements. Given that a new generation of highly mechanistic, genomic-specific global models is not imminent, we suggest that a useful step to improve this situation would be the development of “Decomposition Functional Types” (DFTs). Analogous to plant functional types (PFTs), DFTs would abstract and capture important differences in HR metabolism and flux dynamics, allowing modelers and experimentalists to efficiently group and vary these characteristics across space and time. We argue that DFTs should be initially informed by top-down expert opinion, but ultimately developed using bottom-up, data-driven analyses, and provide specific examples of potential dependent and independent variables that could be used. We present an example clustering analysis to show how annual HR can be broken into distinct groups associated with global variability in biotic and abiotic factors, and demonstrate that these groups are distinct from (but complementary to) already-existing PFTs. A similar analysis incorporating observational data could form the basis for future DFTs. Finally, we suggest next steps and critical priorities: collection and synthesis of existing data; more in-depth analyses combining open data with rigorous testing of analytical results; using point measurements and realistic forcing variables to constrain process-based models; and planning by the global modeling community for decoupling decomposition from fixed site data. These are all critical steps to build a foundation for DFTs in global models, thus providing the ecological and climate change communities with robust, scalable estimates of HR.

  13. Bird strike and electrocutions at power lines, communication towers, and wind turbines: state of the art and state of the science - next steps toward mitigation (United States)

    Albert M. Manville II


    Migratory birds suffer considerable human-caused mortality from structures built to provide public services and amenities. Three such entities are increasing nationwide: communication towers, power lines, and wind turbines. Communication towers have been growing at an exponential rate over at least the past 6 years. The U.S. Fish and Wildlife Service is especially...

  14. Back to business: a next step in the field of oral history: the usefulness of oral history for leadership and organizational research

    NARCIS (Netherlands)

    Keulen, S.; Kroeze, R.


    Business organizations and elites are often neglected in oral history as a result of the dominant assumption that elites have ample opportunity to be heard. We argue, however, that researching corporations and elites is very interesting for oral historians. This contention is supported by the four

  15. Chronically ill patients' self-management abilities to maintain overall well-being: What is needed to take the next step in the primary care setting?

    NARCIS (Netherlands)

    J.M. Cramm (Jane); A.P. Nieboer (Anna)


    textabstractBackground: Although widespread problems in patient-professional interaction and insufficient support of patients' self-management abilities have been recognized, research investigating the relationships among care quality, productive interaction, and self-management abilities to

  16. Chronically ill patients' self-management abilities to maintain overall well-being: what is needed to take the next step in the primary care setting?

    NARCIS (Netherlands)

    J.M. Cramm (Jane); A.P. Nieboer (Anna)


    markdownabstractAbstract Background: Although widespread problems in patient–professional interaction and insufficient support of patients’self-management abilities have been recognized, research investigating the relationships among care quality, productiveinteraction, and self-management

  17. 'Sedentary behaviour counselling': the next step in lifestyle counselling in primary care; pilot findings from the Rapid Assessment Disuse Index (RADI) study. (United States)

    Shuval, Kerem; DiPietro, Loretta; Skinner, Celette Sugg; Barlow, Carolyn E; Morrow, Jay; Goldsteen, Robert; Kohl, Harold W


    Accumulating evidence emphasises a relationship between prolonged sitting and increased risk for cardiometabolic disorders and premature death irrespective of the protective effects of physical activity. Primary care physicians have the potential to play a key role in modifying patients' sedentary behaviour alongside physical activity. A pilot study examining sedentary behaviour and physical activity counselling in a primary care clinic. A total of 157 patients completed a detailed survey related to lifestyle counselling received from their primary care physician. We analysed these responses to describe counselling practices within the 5A framework, and to examine correlates (ie, patients' demographics, sedentary behaviour and physical activity and clinical variables) related to receiving counselling. A total of 10% received general advice to decrease sitting time, in comparison with 53% receiving general physical activity counselling. None, however, received a written plan pertaining to sedentary behaviour whereas 14% received a written physical activity prescription. Only 2% were provided with specific strategies for sedentary behaviour change in comparison with 10% for physical activity change. Multivariable analysis revealed that patients who were obese were more likely to receive counselling to decrease sitting (OR=7.0; 95% CI 1.4 to 35.2). In comparison, higher odds for receiving physical activity counselling were associated with being younger, aged 40-59 years (OR=2.4; 95% CI 1.1 to 5.4); and being a non-smoker (OR=6.1; 95% CI 1.3 to 28.4). This study is the first to assess sedentary behaviour counselling practices in primary care and such practices appear to be infrequent. Future research should attempt to establish a 'knowledge base' to inform development of sedentary behaviour interventions, which should be followed by testing feasibility, efficacy, and subsequent effectiveness of these programmes in a clinical setting. Published by the BMJ Publishing

  18. Variable spreading layer in 4U 1608-52 during thermonuclear X-ray bursts in the soft state (United States)

    Kajava, J. J. E.; Koljonen, K. I. I.; Nättilä, J.; Suleimanov, V.; Poutanen, J.


    Thermonuclear (type-I) X-ray bursts, observed from neutron star (NS) low-mass X-ray binaries (LMXB), provide constraints on NS masses and radii and consequently the equation of state of NS cores. In such analyses, various assumptions are made without knowing if they are justified. We have analysed X-ray burst spectra from the LMXB 4U 1608-52, with the aim of studying how the different persistent emission components react to the bursts. During some bursts in the soft spectral state we find that there are two variable components: one corresponding to the burst blackbody component and another optically thick Comptonized component. We interpret the latter as the spreading layer between the NS surface and the accretion disc, which is not present during the hard-state bursts. We propose that the spectral changes during the soft-state bursts are driven by the spreading layer that could cover almost the entire NS in the brightest phases due to the enhanced radiation pressure support provided by the burst, and that the layer subsequently returns to its original state during the burst decay. When deriving the NS mass and radius using the soft-state bursts two assumptions are therefore not met: the NS is not entirely visible and the burst emission is reprocessed in the spreading layer, causing distortions of the emitted spectrum. For these reasons, the NS mass and radius constraints using the soft-state bursts are different compared to the ones derived using the hard-state bursts.

  19. Integrated concept development of next-step helical-axis advanced stellarators

    Energy Technology Data Exchange (ETDEWEB)

    Warmer, Felix


    With the increasing energy demand of mankind and the transformation of our society towards sustainability, nuclear fusion by magnetic confinement is a promising option for the sustainable electricity supply in the future. In view of these prospects this thesis focuses on the concept development of next-step helical-axis advanced stellarator (HELIAS) burning-plasma devices. The HELIAS-line is the continued development of the prototype optimised stellarator Wendelstein 7-X which started operation in 2015. For the integrated concept development of such devices, the approach taken in this work encompasses detailed physics and engineering considerations while also including economic aspects. Starting with physics considerations, the properties of plasma transport and confinement of 3D stellarator configurations are discussed due to their critical importance for the device design. It becomes clear that current empirical confinement time scalings are not sufficient to predict the confinement in future stellarator devices. Therefore, detailed 1D transport simulations are carried out to reduce the uncertainties regarding confinement. Beyond the well-validated neoclassical approach, first attempts are made to include results from state-of-the-art turbulence simulations into the 1D transport simulations to further enhance the predictive capabilities. Next, for the systematic development of consistent design points, stellarator-specific models are developed and implemented in the well-established European systems code PROCESS. This allows a consistent description of an entire HELIAS fusion power plant including physics, engineering, and economic considerations. With the confidence obtained from a verification study, systems studies are for the first time applied for a HELIAS power-plant which shows that the available design window is constrained by the beta-limit. Furthermore, an economic comparison of an exemplary design point to an ''equivalent'' tokamak

  20. The Next Generation Photoinjector

    Energy Technology Data Exchange (ETDEWEB)

    Palmer, Dennis Thomas; /Stanford U., Appl. Phys. Dept.


    This dissertation will elucidate the design, construction, theory, and operation of the Next Generation Photoinjector (NGP). This photoinjector is comprised of the BNL/SLAC/UCLA 1.6 cell symmetrized S-band photocathode radio frequency (rf) electron gun and a single emittance-compensation solenoidal magnet. This photoinjector is a prototype for the Linear Coherent Light Source X-ray Free Electron Laser operating in the 1.5 {angstrom} range. Simulations indicate that this photoinjector is capable of producing a 1nC electron bunch with transverse normalized emittance less than 1 {pi} mm mrad were the cathode is illuminated with a 10 psec longitudinal flat top pulse. Using a Gaussian longitudinal laser profile with a full width half maximum (FWHM) of 10 psec, simulation indicates that the NGP is capable of producing a normalized rms emittance of 2.50 {pi} mm mrad at 1 nC. Using the removable cathode plate we have studied the quantum efficiency (QE) of both copper and magnesium photo-cathodes. The Cu QE was found to be 4.5 x 10{sup -5} with a 25% variation in the QE across the emitting surface of the cathode, while supporting a field gradient of 125 MV/m. At low charge, the transverse normalized rms emittance, {epsilon}{sub n,rms}, produced by the NGP is {epsilon}{sub n,rms} = 1.2 {pi} mm mrad for Q{sub T} = 0.3 nC. The 95% electron beam bunch length was measured to 10.9 psec. The emittance due to the finite magnetic field at the cathode has been studied. The scaling of this magnetic emittance term as a function of cathode magnetic field was found to be 0.01 {pi} mm mrad per Gauss. The 1.6 cell rf gun has been designed to reduce the dipole field asymmetry of the longitudinal accelerating field. Low level rf measurements show that this has in fact been accomplished, with an order of magnitude decrease in the dipole field. High power beam studies also show that the dipole field has been decreased. An upper limit of the intrinsic non-reducible thermal emittance of a

  1. Thermonuclear microdetonation macron accelerator for impact ignition (United States)

    Winterberg, F.


    It is proposed to replace the expensive ~150 kJ petawatt laser as a means for the fast ignition of a highly compressed dense DT target by a small flyer plate propelled to high velocities by a thermonuclear microdetonation ignited at one end of a super-pinch. It appears that this can most efficiently be done with the previously proposed modification of the dense plasma focus device, adding a high voltage relativistic electron beam emitting diode inside the coaxial plasma focus discharge tube, igniting at the end of the plasma focus pinch column a thermonuclear detonation wave, propagating in the axial direction and accelerating at the end of the pinch a flyer plate to a velocity of 103 km s-1.

  2. Electric-stepping-motor tests for a control-drum actuator of a nuclear reactor (United States)

    Kieffer, A. W.


    Experimental tests were conducted on two stepping motors for application as reactor control-drum actuators. Various control-drum loads with frictional resistances ranging from approximately zero to 40 N-m and inertias ranging from zero to 0.424 kg-sq m were tested.

  3. High gamma-rays irradiation tests of critical components for ITER (International Thermonuclear Experimental Reactor) in-vessel remote handling system

    Energy Technology Data Exchange (ETDEWEB)

    Obara, Kenjiro; Kakudate, Satoshi; Oka, Kiyoshi [Department of Fusion Engineering Research, Naka Fusion Research Establishment, Japan Atomic Energy Research Institute, Naka, Ibaraki (Japan)] [and others


    In ITER, the in-vessel remote handling is inevitably required to assemble and maintain the activated in-vessel components due to deuterium and tritium operation. Since the in-vessel remote handling system has to be operated under the intense of gamma ray irradiation, the components of the remote handling system are required to have radiation hardness so as to allow maintenance operation for a sufficient length of time under the ITER in-vessel environments. For this, the Japan, European and Russian Home Teams have extensively conducted gamma ray irradiation tests and quality improvements including optimization of material composition through ITER R and D program in order to develop radiation hard components which satisfy the doses from 10 MGy to 100 MGy at a dose rate of 1 x 10{sup 6} R/h (ITER R and D Task: T252). This report describes the latest status of radiation hard component development which has been conducted by the Japan Home Team in the ITER R and D program. The number of remote handling components tested is about seventy and these are categorized into robotics (Subtask 1), viewing system (Subtask 2) and common components (Subtask 3). The irradiation tests, including commercial base products for screening, modified products and newly developed products to improve the radiation hardness, were carried out using the gamma ray irradiation cells in Takasaki Establishment, JAERI. As a result, the development of the radiation hard components which can be tolerable for high temperature and gamma radiation has been well progressed, and many components, such as AC servo motor with ceramics insulated wire, optical periscope and CCD camera, have been newly developed. (author)

  4. Palliative care for patients with Parkinson’s disease: an interdisciplinary review and next step model

    Directory of Open Access Journals (Sweden)

    Su KG


    Full Text Available Kimmy G Su,1 Julie H Carter,1 Keiran K Tuck,2 Tony Borcich,3 Linda A Bryans,4 Lisa L Mann,1 Jennifer L Wilhelm,5 Erik K Fromme6 1Department of Neurology, Oregon Health & Science University, 2The Oregon Clinic-Neurology, 3Parkinson’s Resources of Oregon, 4Northwest Clinic for Voice and Swallowing, Oregon Health and Science University, 5Rehabilitation Services, Oregon Health & Science University, 6Palliative Care Section, OHSU Knight Cancer Institute, Portland, OR, USA Abstract: Late stage Parkinson’s and Parkinson-plus patients have increased needs beyond motor symptom management that cannot be fully addressed in a typical neurology clinic visit. Complicating matters are the concurrent increasing emotional and physical demands on caregivers, which, if addressed, further stretch clinic time constraints. The complex and extensive patient and caregiver needs warrant a dedicated clinic to provide the necessary interdisciplinary care. In contrast to a typical model where the neurology clinician refers the patient to various ancillary treatment groups resulting in multiple separate clinic visits, the interdisciplinary model supports direct communication between the different disciplines during the clinic visit, allowing for a more coordinated response that takes into account multiple perspectives. Such an interdisciplinary model has been utilized in neurologic disorders with complex end-stage disease needs, such as amyotrophic lateral sclerosis with notable improvement in quality of life and survival. The Oregon Health & Science University Parkinson Center and Movement Disorders Clinic has developed an interdisciplinary clinic called Next Step composed of neurology clinicians, a physical therapist, a speech pathologist, a social worker, and a nursing coordinator. The clinic focuses on palliative care issues, including complex late stage motor symptoms, nonmotor symptoms, and quality of life goals of both the patient and caregiver(s. This article

  5. Thermonuclear Quenching in Flame-Vortex Interactions (United States)

    Zingale, M.; Niemeyer, J. C.; Timmes, F. X.; Dursi, L. J.; Calder, A. C.; Fryxell, B.; Olson, K.; Ricker, P.; Rosner, R.; Truran, J. W.; Tufo, H.; MacNeice, P.


    A Type Ia supernova begins as a flame, deep in the interior of a white dwarf. At some point, the burning may undergo a deflagration-detonation transition (DDT). Some mechanisms for this transition require a preconditioned region in the star. As the flame propagates down the temperature gradient, the speed increases, and the transition to a detonation may occur (see Khokhlov et al. 1997; Niemeyer & Woosley 1997). For this to happen, the region must be free of any temperature fluctuations -- any burning must be quenched. We show direct numerical simulations of flame-vortex interactions in order to understand quenching of thermonuclear flames. The key question is -- can a thermonuclear flame be quenched? If not, the DDT mechanisms that demand the finely tuned preconditioned region are unlikely to work. In these simulations, we pass a steady-state laminar flame through a vortex pair. The vortex pair represents the most severe strain the flame front will encounter inside the white dwarf. We perform a parameter study, varying the speed and size of the vortex pair, in order to understand the quenching process. These simulations were carried out with the FLASH Code. This work is supported by the Department of Energy under Grant No. B341495 to the Center for Astrophysical Thermonuclear Flashes at the University of Chicago. These calculations were performed on the Nirvana Cluster at Los Alamos National Laboratory

  6. Outlook: The Next Twenty Years

    Energy Technology Data Exchange (ETDEWEB)

    Murayama, Hitoshi


    I present an outlook for the next twenty years in particle physics. I start with the big questions in our field, broken down into four categories: horizontal, vertical, heaven, and hell. Then I discuss how we attack the bigquestions in each category during the next twenty years. I argue for a synergy between many different approaches taken in our field.

  7. Registration of Multi-Level Property Rights in 3D in The Netherlands: Two Cases and Next Steps in Further Implementation

    Directory of Open Access Journals (Sweden)

    Jantien Stoter


    Full Text Available This article reports on the first 3D cadastral registration in The Netherlands, accomplished in March 2016. The solution was sought within the current cadastral, organisational, and technical frameworks to obtain a deeper knowledge on the optimal way of implementing 3D registration, while avoiding discussions between experts from different domains. The article presents the developed methodology to represent legal volumes in an interactive 3D visualisation that can be registered in the land registers. The source data is the 3D Building Information Model (BIM. The methodology is applied to two cases: (1 the case of the railway station in Delft, resulting in the actual 3D registration in 2016; and (2 a building complex in Amsterdam, improving the Delft-case and providing the possibility to describe a general workflow from design data to a legal document. An evaluation provides insights for an improved cadastral registration of multi-level property rights. The main conclusion is that in specific situations, a 3D approach has important advantages for cadastral registration over a 2D approach. Further study is needed to implement the solution in a standardised and uniform way, from registration to querying and updating in the future, and to develop a formal registration process accordingly.

  8. Modelling the interaction of thermonuclear supernova remnants with circumstellar structures: the case of Tycho's supernova remnant (United States)

    Chiotellis, A.; Kosenko, D.; Schure, K. M.; Vink, J.; Kaastra, J. S.


    The well-established Type Ia remnant of Tycho's supernova (SN 1572) reveals discrepant ambient medium-density estimates based on either the measured dynamics or the X-ray emission properties. This discrepancy can potentially be solved by assuming that the supernova remnant (SNR) shock initially moved through a stellar wind bubble, but is currently evolving in the uniform interstellar medium with a relatively low density. We investigate this scenario by combining hydrodynamical simulations of the wind-loss phase and the SNR evolution with a coupled X-ray emission model, which includes non-equilibrium ionization. For the explosion models we use the well-known W7 deflagration model and the delayed detonation model that was previously shown to provide good fits to the X-ray emission of Tycho's SNR. Our simulations confirm that a uniform ambient density cannot simultaneously reproduce the dynamical and X-ray emission properties of Tycho. In contrast, models that considered that the remnant was evolving in a dense, but small, wind bubble reproduce reasonably well both the measured X-ray emission spectrum and the expansion parameter of Tycho's SNR. Finally, we discuss possible mass-loss scenarios in the context of single- and double-degenerate models which possibly could form such a small dense wind bubble.

  9. Modelling the interaction of thermonuclear supernova remnants with circumstellar structures: the case of Tycho's supernova remnant

    NARCIS (Netherlands)

    Chiotellis, A.; Kosenko, D.; Schure, K.M.; Vink, J.; Kaastra, J.S.


    The well-established Type Ia remnant of Tycho's supernova (SN 1572) reveals discrepant ambient medium-density estimates based on either the measured dynamics or the X-ray emission properties. This discrepancy can potentially be solved by assuming that the supernova remnant (SNR) shock initially

  10. Fast Ignition Thermonuclear Fusion: Enhancement of the Pellet Gain by the Colossal-Magnetic-Field Shells (United States)

    Stefan, V. Alexander


    The fast ignition fusion pellet gain can be enhanced by a laser generated B-field shell. The B-field shell, (similar to Earth's B-field, but with the alternating B-poles), follows the pellet compression in a frozen-in B-field regime. A properly designed laser-pellet coupling can lead to the generation of a B-field shell, (up to 100 MG), which inhibits electron thermal transport and confines the alpha-particles. In principle, a pellet gain of few-100s can be achieved in this manner. Supported in part by Nikola Tesla Labs, Stefan University, 1010 Pearl, La Jolla, CA 92038-1007.

  11. Foreign remedies: what the experience of other nations can tell us about next steps in reforming U.S. health care

    National Research Council Canada - National Science Library

    Rochefort, David A; Donnelly, Kevin P


    "The Patient Protection and Affordable Care Act marked a watershed in U.S. health policy, but controversy over its passage rages on, and much uncertainty surrounds the law's transformation from blueprint into operational program...

  12. Soft-Body Muscles for Evolved Virtual Creatures: The Next Step on a Bio-Mimetic Path to Meaningful Morphological Complexity

    DEFF Research Database (Denmark)

    Lessin, Dan; Risi, Sebastian


    In the past, evolved virtual creatures (EVCs) have been developed with rigid, segmented bodies, and with soft bodies, but never before with a combination of the two. In nature, however, creatures combining a rigid skeleton and non-rigid muscles are some of the most complex and successful examples...

  13. The EuCARD2 Future Magnets Program for Particle Accelerator High-Field Dipoles : Review of Results and Next Steps

    NARCIS (Netherlands)

    Rossi, Lucio; Badel, Arnaud; Bajas, Hugues; Bajko, Marta; Ballarino, Amalia; Barth, Christian; Betz, Ulrich; Bottura, Luca; Broggi, Francesco; Chiuchiolo, Antonella; Dhalle, Marc; Durante, Maria; Fazilleau, Philippe; Fleiter, Jerome; Gao, Peng; Goldacker, Wilfried; Kario, Anna; Kirby, Glyn; Haro, E.; Himbele, J.; Lorin, C.; Murtomaki, J.; Van Nugteren, Jeroen; Petrone, Carlo; De Rijk, Gijs; Ruuskanen, J.; Senatore, Carmine; Statera, Marco; Stenvall, Antti; Tixador, Pascal; Yang, Yifeng; Usoskin, Alexander; Zangenberg, Nikolaj

    The EuCARD2 collaboration aims at the development of a 10 kA-class superconducting, high current density cable suitable for accelerator magnets, to be tested in small coils and magnets capable to deliver 3-5 T when energized in stand-alone mode, and 15-18 T when inserted in a 12-13 T background

  14. Understanding the association between stunting and child development in low- and middle-income countries: Next steps for research and intervention. (United States)

    Perkins, Jessica M; Kim, Rockli; Krishna, Aditi; McGovern, Mark; Aguayo, Victor M; Subramanian, S V


    Stunting, caused by experiences of chronic nutritional deprivation, affects approximately 25% of children under age five globally (i.e., 156 million children). In this review, evidence of a relationship between stunting and child development in low- and middle-income countries is summarized, and issues for further research are discussed. We focus on studies that measured low height-for-age among children less than 5 years old as the exposure and gross/fine motor skills, psychosocial competencies, cognitive abilities, or schooling and learning milestones as the outcomes. This review highlights three key findings. First, the variability in child development tools and metrics used among studies and the differences in the timing and frequency of the assessments complicate comparisons across study findings. Second, considerable evidence from across many countries supports an association between stunting and poor child development despite methodological differences and heterogeneity in the magnitude of associations. Further, effect sizes differ by developmental domain with greater associations shown for cognitive/schooling outcomes. How stunting influences child development, which domains of child development are more affected, and how the various domains of child development influence one another require further experimental research to test causal pathways. Finally, there is mixed evidence of the additive effect of nutrition + stimulation interventions on child development. However, understanding best methods for improving child developmental outcomes - either through nutrition programs or through integrated nutrition + psychosocial stimulation programs (or nutrition + other program interventions) - is a key area of further inquiry. Given that nearly 40% of children under age five suffer from loss of developmental potential - for which stunting is likely one of the key risk factors - reductions in stunting could have tremendous implications for child development

  15. Initial Steps Toward Next-Generation, Waveform-Based, Three-Dimensional Models and Metrics to Improve Nuclear Explosion Monitoring in the Middle East (United States)


    propagation effects by splitting apart the longer period surface waves from the shorter period, depth-sensitive Pnl waves. Problematic, or high-error... Pnl waves. Problematic, or high-error, stations and paths were further analyzed to identify systematic errors with unknown sensor responses and...frequency Pnl components and slower, longer period surface waves. All cut windows are fit simultaneously, allowing equal weighting of phases that may be

  16. CBT in the prevention of psychosis and other severe mental disorders in patients with an at risk mental state: A review and proposed next steps. (United States)

    van der Gaag, Mark; van den Berg, David; Ising, Helga


    Patients with an 'At risk mental state' (ARMS) for developing psychosis can be treated successfully with CBT to postpone and prevent the transition to a first psychotic episode. A characteristic of individuals that meet ARMS criteria is that they are still open for multiple explanations for extraordinary experiences. CBT aims to normalize extraordinary experiences with education and to prevent delusional explanations. The treatment is not only effective, but also cost-saving in averting psychosis as well as in reducing disability adjusted life years at 18- and 48-month follow-up. Profiling within the ARMS group results in a personalized treatment. The screening and early treatment for ARMS fulfills all the criteria of the World Health Organization and is ready to be routine screening and treatment in mental health care. At the same time, ARMS patients are complex patients with multi-morbid disorders. Especially childhood trauma is associated to ARMS status, together with co-morbid PTSD, depression, substance abuse and anxiety disorders. Psychotic symptoms appear to be severity markers in other non-psychotic disorders. Preventing psychosis in ARMS patients should be broadened to also address other disorders and aim to reduce chronicity of psychopathology and improve social functioning in general. Several mechanisms play a part in psychopathology in ARMS patients such as stress sensitivity as a result of adverse experiences, dopamine sensitivity that is associated with salience and aggravates several cognitive biases, dissociation mediating between trauma and hallucinations, and low self-esteem and self-stigma. New avenues to treat the complexity of ARMS patients will be proposed. Copyright © 2017 Elsevier B.V. All rights reserved.

  17. The Next Step in School Choice

    National Research Council Canada - National Science Library

    Matthew Ladner


    ...: private-school tuition, tutoring from certified tutors, individual public-school courses, online programs, community college and university tuition, standardized testing fees, curriculum costs...

  18. The LOFT perspective on neutron star thermonuclear bursts: White paper in support of the mission concept of the large observatory for X-ray timing

    Energy Technology Data Exchange (ETDEWEB)

    in' t Zand, J. J.M. [SRON Netherlands Institute for Space Research, Utrecht (The Netherlands); Malone, Christopher M. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Altamirano, D. [Univ. of Southampton, Southampton (United Kingdom); Ballantyne, D. R. [Georgia Inst. of Technology, Atlanta, GA (United States); Bhattacharyya, S. [Tata Institute of Fundamental Research, Mumbai (India); Brown, E. F. [Michigan State Univ., East Lansing, MI (United States); Cavecchi, Y. [Univ. of Amsterdam, Amsterdam (The Netherlands); Chakrabarty, D. [Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States); Chenevez, J. [Technical Univ. of Denmark, Lyngby (Denmark); Cumming, A. [McGill Univ., Montreal, QC (Canada); Degenaar, N. [Univ. of Cambridge, Cambridge (United Kingdom); Falanga, M. [International Space Science Institute, Bern (Switzerland); Galloway, D. K. [Monash Univ., VIC (Australia); Heger, A. [Monash Univ., VIC (Australia); Jose, J. [Univ. Politecnica de Catalunya, Barcelona (Spain); Institut d' Estudis Espacials de Catalunya, Barcelona (Spain); Keek, L. [Georgia Institute of Technology, Atlanta, GA (United States); Linares, M. [Univ. de La Laguna, Tenerife (Spain); Mahmoodifar, S. [Univ. of Maryland, College Park, MD (United States); Mendez, M. [Univ. of Groningen, Groningen (The Netherlands); Miller, M. C. [Univ. of Maryland, College Park, MD (United States); Paerels, F. B. S. [Columbia Astrophysics Lab., New York, NY (United States); Poutanen, J. [Univ. of Turku, Piikkio (Finland); Rozanska, A. [N. Copernicus Astronomical Center PAS, Warsaw (Poland); Schatz, H. [National Superconducting Cyclotron Laboratory at Michigan State University; Serino, M. [Institute of Physical and Chemical Research (RIKEN); Strohmayer, T. E. [NASA' s Goddard Space Flight Center, Greenbelt, MD (United States); Suleimanov, V. F. [Univ. Tubingen, Tubingen (Germany); Thielemann, F. -K. [Univ. Basel, Basel (Switzerland); Watts, A. L. [Univ. of Amsterdam, Amsterdam (The Netherlands); Weinberg, N. N. [Massachusetts Institute of Technology, Cambridge, MA (United States); Woosley, S. E. [Univ. of California, Santa Cruz, CA (United States); Yu, W. [Chinese Academy of Sciences (CAS), Shanghai (China); Zhang, S. [Institute of High-Energy Physics, Beijing (China); Zingale, M. [Stony Brook Univ., Stony Brook, NY (United States)


    The Large Area Detector (LAD) on the Large Observatory For X-ray Timing ( LOFT ), with a 8.5 m 2 photon- collecting area in the 2–30 keV bandpass at CCD-class spectral resolving power (λ/Δλ = 10 – 100), is designed for optimum performance on bright X-ray sources. Thus, it is well-suited to study thermonuclear X-ray bursts from Galactic neutron stars. These bursts will typically yield 2 x 105 photon detections per second in the LAD, which is at least 15 times more than with any other instrument past, current or anticipated. The Wide Field Monitor (WFM) foreseen for LOFT uniquely combines 2–50 keV imaging with large (30%) prompt sky coverage. This will enable the detection of tens of thousands of thermonuclear X-ray bursts during a 3-yr mission, including tens of superbursts. Both numbers are similar or more than the current database gathered in 50 years of X-ray astronomy.

  19. The apeNEXT project (United States)

    Belletti, F.; Bodin, F.; Boucaud, Ph.; Cabibbo, N.; Lonardo, A.; de Luca, S.; Lukyanov, M.; Micheli, J.; Morin, L.; Pene, O.; Pleiter, D.; Rapuano, F.; Rossetti, D.; Schifano, S. F.; Simma, H.; Tripiccione, R.; Vicini, P.; apeNEXT Collaboration


    Numerical simulations in theoretical high-energy physics (Lattice QCD) require huge computing resources. Several generations of massively parallel computers optimised for these applications have been developed within the APE (array processor experiment) project. Large prototype systems of the latest generation, apeNEXT, are currently being assembled and tested. This contribution explains how the apeNEXT architecture is optimised for Lattice QCD, provides an overview of the hardware and software of apeNEXT, and describes its new features, like the SPMD programming model and the C compiler.

  20. Development of an Advanced Computational Fluid Dynamics Technology for the Next-Generation Nuclear Reactor System Analysis and Safety Margin Characterization Code

    Energy Technology Data Exchange (ETDEWEB)

    Luo, Hong [North Carolina State Univ., Raleigh, NC (United States); Nourgaliev, Robert [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)


    This report describes the research activities we have conducted at NCSU for our NEUP project. The work toward achieving the objectives of the project is reported. The significant achievements and accomplishments are presented. A number of numerical experiments are conducted to demonstrate that the goal of the proposed work has been successfully achieved. Issues, recommendations, and future work are discussed.

  1. The Joint European Torus (JET) (United States)

    Rebut, Paul-Henri


    This paper addresses the history of JET, the Tokamak that reached the highest performances and the experiment that so far came closest to the eventual goal of a fusion reactor. The reader must be warned, however, that this document is not a comprehensive study of controlled thermonuclear fusion or even of JET. The next step on this road, the ITER project, is an experimental reactor. Actually, several prototypes will be required before a commercial reactor can be built. The fusion history is far from been finalised. JET is still in operation some 32 years after the first plasma and still has to provide answers to many questions before ITER takes the lead on research. Some physical interpretations of the observed phenomena, although coherent, are still under discussion. This paper also recalls some basic physics concepts necessary to the understanding of confinement: a knowledgeable reader can ignore these background sections. This fascinating story, comprising successes and failures, is imbedded in the complexities of twentieth and the early twenty-first centuries at a time when world globalization is evolving and the future seems loaded with questions. The views here expressed on plasma confinement are solely those of the author. This is especially the case for magnetic turbulence, for which other scientists may have different views.

  2. Sensitivity to Thermonuclear Reaction Rates in Modeling the Abundance Anomalies of NGC 2419 (United States)

    Dermigny, J. R.; Iliadis, C.


    Abundance anomalies in globular clusters provide strong evidence for multiple stellar populations within each cluster. These populations are usually interpreted as distinct generations, with the currently observed second-generation stars having formed in part from the ejecta of massive, first-generation “polluter” stars, giving rise to the anomalous abundance patterns. The precise nature of the polluters and their enrichment mechanism are still unclear. Even so, the chemical abundances measured in second-generation stars within the globular cluster NGC 2419 provide insight into this puzzling process. Previous work used Monte Carlo nuclear reaction network calculations to constrain the temperature-density conditions that could reproduce the observed abundances, thereby placing robust limits on the origins of the polluter material. The effect of individual reaction rates on these conditions has not been studied, however. Thus, we perform an exhaustive sensitivity study on the nuclear physics input to determine which reactions have the greatest impact on these predictions. We find that the {}30Si(p,γ){}31P, {}37Ar(p,γ){}38K, {}38Ar(p,γ){}39K, and {}39K(p,γ){}40Ca reactions are all critical in determining the temperature-density conditions, and ultimately, the origins of the polluter material. We conclude with recommendations for future experiments.

  3. The Response of Model and Astrophysical Thermonuclear Flames to Curvature and Stretch (United States)

    Dursi, L. J.; Zingale, M.; Calder, A. C.; Fryxell, B.; Timmes, F. X.; Vladimirova, N.; Rosner, R.; Caceres, A.; Lamb, D. Q.; Olson, K.; Ricker, P. M.; Riley, K.; Siegel, A.; Truran, J. W.


    Critically understanding the standard candle-like behavior of Type Ia supernovae requires understanding their explosion mechanism. One family of models for Type Ia supernovae begins with a deflagration in a carbon-oxygen white dwarf that greatly accelerates through wrinkling and flame instabilities. While the planar speed and behavior of astrophysically relevant flames is increasingly well understood, more complex behavior, such as the flame's response to stretch and curvature, has not been extensively explored in the astrophysical literature; this behavior can greatly enhance or suppress instabilities and local flame-wrinkling, which in turn can increase or decrease the bulk burning rate. In this paper, we explore the effects of curvature on both nuclear flames and simpler model flames to understand the effect of curvature on the flame structure and speed.

  4. Next-to-next-to-eikonal corrections in the CGC

    Energy Technology Data Exchange (ETDEWEB)

    Altinoluk, Tolga; Armesto, Néstor [Departamento de Física de Partículas and IGFAE,Universidade de Santiago de Compostela,E-15706 Santiago de Compostela, Galicia (Spain); Beuf, Guillaume [Department of Physics, Ben-Gurion University of the Negev,Beer Sheva 84105 (Israel); Moscoso, Alexis [Departamento de Física de Partículas and IGFAE,Universidade de Santiago de Compostela,E-15706 Santiago de Compostela, Galicia (Spain)


    We extend the study of corrections to the eikonal approximation that was initiated in ref. to higher orders. These corrections associated with the finite width of the target are investigated and the gluon propagator in background field is calculated at next-to-next-to-eikonal accuracy. The result is then applied to the single inclusive gluon production cross section at central rapidities and the single transverse spin asymmetry with a transversely polarized target, in pA collisions, in order to analyze these observables beyond the eikonal limit. The next-to-next-to-eikonal corrections to the unpolarized cross section are non-zero and provide the first corrections to the usual k{sub ⊥}-factorized expression. In contrast, the eikonal and next-to-next-to-eikonal contributions to the single transverse spin asymmetry vanish, while the next-to-eikonal ones are non-zero.

  5. Neutron star cooling and the rp process in thermonuclear X-ray bursts

    DEFF Research Database (Denmark)

    Zand, J. J. M. in 't; Visser, M. E. B.; Galloway, D.K.


    When the upper layer of an accreting neutron star experiences a thermonuclearrunaway of helium and hydrogen, it exhibits an X-ray burst of a few keV with acool-down phase of typically 1~minute. When there is a surplus of hydrogen,hydrogen fusion is expected to simmer during that same minute due...

  6. Thermonuclear Propaganda: Presentations of Nuclear Strategy in the Early Atomic Age (United States)


    223 Howard, War and the Liberal Conscience, 126. 224 Hannah Arendt , On Violence (New York: Harcourt Inc., 1969), 75...details/isforAto1953. Arendt , Hannah. On Violence. New York: Harcourt, 1969. Acheson, Dean. Department of State Bulletin. 1 October 1951. Quoted in Ian

  7. Project of law, adopted by the Senate, giving permission to the approval of the agreement between the French government and the international organization for thermonuclear fusion energy ITER, relative to the head office of ITER organization and to the privileges and immunities of ITER organization in the French territory; Projet de loi adopte par le Senat, autorisant l'approbation de l'accord entre le Gouvernement de la Republique francaise et l'Organisation internationale ITER pour l'energie de fusion relatif au siege de l'Organisation ITER et aux privileges et immunites de l'Organisation ITER sur le territoire francais

    Energy Technology Data Exchange (ETDEWEB)



    The will of building up an international thermonuclear experimental reactor (ITER) gathers since several years the European community of atomic energy (Euratom), Japan, the USA, and Russia, next followed by China, South Korea and, since 2005, by India. The agreement signed in Paris between these seven parties on November 21, 2006 entrusted the international organization ITER with the realization of this project. The implications of the ITER project are enormous both in their scientific and in their economical aspects. France has a particular position in this project since the head office of ITER organisation is sited at Saint-Paul-lez-Durance and the tokamak will be built at Cadarache. Therefore, an agreement has been signed between ITER organization and the French government. The approval of this agreement is the object of this project of law made of a single article. The agreement between the French government and the international organization ITER is attached to the document. It defines the juridical status, the privileges and immunities of the organization itself and of its personnel inside the French territory. An appendix to the agreement precises the cooperation modalities between the French authorities and ITER organization. (J.S.)

  8. Results of the Nucifer reactor neutrino experiment

    Energy Technology Data Exchange (ETDEWEB)

    Buck, Christian; Lindner, Manfred [MPIK Heidelberg (Germany)


    Nuclear reactors are a strong and pure source of electron antineutrinos. With neutrino experiments close to compact reactor cores new insights into neutrino properties and reactor physics can be obtained. The Nucifer experiment is one of the pioneers in this class of very short baseline projects. Its detector to reactor distance is only about 7 m. The data obtained in the last years allowed to estimate the plutonium concentration in the reactor core by the neutrino flux measurement. This is of interest for safeguard applications and non proliferation efforts. The antineutrinos in Nucifer are detected via the inverse beta decay on free protons. Those Hydrogen nuclei are provided by 850 liters of organic liquid scintillator. For higher detection efficiency and background reduction the liquid is loaded with Gadolinium. Despite all shielding efforts and veto systems the background induced by the reactor activity and cosmogenic particles is still the main challenge in the experiment. The principle of the Nucifer detector is similar to the needs of upcoming experiments searching for sterile neutrinos. Therefore, the Nucifer results are also valuable input for the understanding and optimization of those next generation projects. The observation of sterile neutrinos would imply new physics beyond the standard model.

  9. Emerging technologies to measure neighborhood conditions in public health: implications for interventions and next steps. (United States)

    Schootman, M; Nelson, E J; Werner, K; Shacham, E; Elliott, M; Ratnapradipa, K; Lian, M; McVay, A


    Adverse neighborhood conditions play an important role beyond individual characteristics. There is increasing interest in identifying specific characteristics of the social and built environments adversely affecting health outcomes. Most research has assessed aspects of such exposures via self-reported instruments or census data. Potential threats in the local environment may be subject to short-term changes that can only be measured with more nimble technology. The advent of new technologies may offer new opportunities to obtain geospatial data about neighborhoods that may circumvent the limitations of traditional data sources. This overview describes the utility, validity and reliability of selected emerging technologies to measure neighborhood conditions for public health applications. It also describes next steps for future research and opportunities for interventions. The paper presents an overview of the literature on measurement of the built and social environment in public health (Google Street View, webcams, crowdsourcing, remote sensing, social media, unmanned aerial vehicles, and lifespace) and location-based interventions. Emerging technologies such as Google Street View, social media, drones, webcams, and crowdsourcing may serve as effective and inexpensive tools to measure the ever-changing environment. Georeferenced social media responses may help identify where to target intervention activities, but also to passively evaluate their effectiveness. Future studies should measure exposure across key time points during the life-course as part of the exposome paradigm and integrate various types of data sources to measure environmental contexts. By harnessing these technologies, public health research can not only monitor populations and the environment, but intervene using novel strategies to improve the public health.

  10. A review of the US joining technologies for plasma facing components in the ITER fusion reactor

    Energy Technology Data Exchange (ETDEWEB)

    Odegard, B.C. Jr.; Cadden, C.H. [Sandia National Labs., Livermore, CA (United States); Watson, R.D. [Sandia National Labs., Albuquerque, NM (United States); Slattery, K.T. [Boeing Co., St. Louis, MO (United States)


    This paper is a review of the current joining technologies for plasma facing components in the US for the International Thermonuclear Experimental Reactor (ITER) project. Many facilities are involved in this project. Many unique and innovative joining techniques are being considered in the quest to join two candidate armor plate materials (beryllium and tungsten) to a copper base alloy heat sink (CuNiBe, OD copper, CuCrZr). These techniques include brazing and diffusion bonding, compliant layers at the bond interface, and the use of diffusion barrier coatings and diffusion enhancing coatings at the bond interfaces. The development and status of these joining techniques will be detailed in this report.

  11. Spin-charge-family theory is offering next step in understanding elementary particles and fields and correspondingly universe (United States)

    Mankoč Borštnik, Norma Susana


    More than 40 years ago the standard model made a successful new step in understanding properties of fermion and boson fields. Now the next step is needed, which would explain what the standard model and the cosmological models just assume: a. The origin of quantum numbers of massless one family members. b. The origin of families. c. The origin of the vector gauge fields. d. The origin of the Higgses and Yukawa couplings. e. The origin of the dark matter. f. The origin of the matter-antimatter asymmetry. g. The origin of the dark energy. h. And several other open problems. The spin-charge-family theory, a kind of the Kaluza-Klein theories in (d = (2n - 1) + 1)-space-time, with d = (13 + 1) and the two kinds of the spin connection fields, which are the gauge fields of the two kinds of the Clifford algebra objects anti-commuting with one another, may provide this much needed next step. The talk presents: i. A short presentation of this theory. ii. The review over the achievements of this theory so far, with some not published yet achievements included. iii. Predictions for future experiments.

  12. The next big accelerator

    CERN Multimedia

    Cramer, J G


    Accelerator physics in the US has been devastated by the cancellation of two high-energy physics colliders facilities. However there are future plans. A suggestion is made to build the new collider in the Australian outback.

  13. Raising the Next Generation (United States)

    Napper-Owen, Gloria


    Amy Morris Homans had a vision that graduates of the Boston Normal School of Gymnastics and Wellesley College would make physical education a well-respected profession. The professional preparation received by her students equipped them to be educators, administrators, and future leaders of physical education. The purpose of this essay is to…

  14. The next scientific revolution. (United States)

    Hey, Tony


    For decades, computer scientists have tried to teach computers to think like human experts. Until recently, most of those efforts have failed to come close to generating the creative insights and solutions that seem to come naturally to the best researchers, doctors, and engineers. But now, Tony Hey, a VP of Microsoft Research, says we're witnessing the dawn of a new generation of powerful computer tools that can "mash up" vast quantities of data from many sources, analyze them, and help produce revolutionary scientific discoveries. Hey and his colleagues call this new method of scientific exploration "machine learning." At Microsoft, a team has already used it to innovate a method of predicting with impressive accuracy whether a patient with congestive heart failure who is released from the hospital will be readmitted within 30 days. It was developed by directing a computer program to pore through hundreds of thousands of data points on 300,000 patients and "learn" the profiles of patients most likely to be rehospitalized. The economic impact of this prediction tool could be huge: If a hospital understands the likelihood that a patient will "bounce back," it can design programs to keep him stable and save thousands of dollars in health care costs. Similar efforts to uncover important correlations that could lead to scientific breakthroughs are under way in oceanography, conservation, and AIDS research. And in business, deep data exploration has the potential to unearth critical insights about customers, supply chains, advertising effectiveness, and more.

  15. LOBSTER - The Next Generation (United States)

    Schwenk, Arne


    Since 1997 K.U.M. GmbH designs and manufactures Ocean Bottom Seismometer. During the last three years we designed a new instrument which is presented here. Higher resolution, higher accuracy and less power consumption led to an unique instrument, the worlds smallest broadband longterm OBS. Key data are: 32 bit, 143dB, 300mW, 120 sec, 200kg deployment weight, size of half a palette.

  16. Single-step processing of copper-doped titania nanomaterials in a flame aerosol reactor

    Directory of Open Access Journals (Sweden)

    Sahu Manoranjan


    Full Text Available Abstract Synthesis and characterization of long wavelength visible-light absorption Cu-doped TiO2 nanomaterials with well-controlled properties such as size, composition, morphology, and crystal phase have been demonstrated in a single-step flame aerosol reactor. This has been feasible by a detailed understanding of the formation and growth of nanoparticles in the high-temperature flame region. The important process parameters controlled were: molar feed ratios of precursors, temperature, and residence time in the high-temperature flame region. The ability to vary the crystal phase of the doped nanomaterials while keeping the primary particle size constant has been demonstrated. Results indicate that increasing the copper dopant concentration promotes an anatase to rutile phase transformation, decreased crystalline nature and primary particle size, and better suspension stability. Annealing the Cu-doped TiO2 nanoparticles increased the crystalline nature and changed the morphology from spherical to hexagonal structure. Measurements indicate a band gap narrowing by 0.8 eV (2.51 eV was achieved at 15-wt.% copper dopant concentration compared to pristine TiO2 (3.31 eV synthesized under the same flame conditions. The change in the crystal phase, size, and band gap is attributed to replacement of titanium atoms by copper atoms in the TiO2 crystal.

  17. I(sup STAR), NASA's Next Step in Air-Breathing Propulsion for Space Access (United States)

    Hutt, John J.; McArthur, Craig; Cook, Stephen (Technical Monitor)


    The United States' National Aeronautics and Space Administration (NASA) has established a strategic plan for future activities in space. A primary goal of this plan is to make drastic improvements in the cost and safety of earth to low-earth-orbit transportation. One approach to achieving this goal is through the development of highly reusable, highly reliable space transportation systems analogous to the commercial airline system. In the year 2000, NASA selected the Rocket Based Combined Cycle (RBCC) engine as the next logical step towards this goal. NASA will develop a complete flight-weight, pump-fed engine system under the Integrated System Test of an Airbreathing Rocket (I(sup STAR)) Project. The objective of this project is develop a reusable engine capable of self-powering a vehicle through the air-augmented rocket, ramjet and scramjet modes required in all RBCC based operational vehicle concepts. The project is currently approved and funded to develop the engine through ground test demonstration. Plans are in place to proceed with flight demonstration pending funding approval. The project is in formulation phase and the Preliminary Requirements Review has been completed. The engine system and vehicle have been selected at the conceptual level. The I(sup STAR) engine concept is based on an air-breathing flowpath downselected from three configurations evaluated in NASA's Advanced Reusable Technology contract. The selected flowpath features rocket thrust chambers integrated into struts separating modular flowpath ducts, a variable geometry inlet, and a thermally choked throat. The engine will be approximately 220 inches long and 79 inches wide and fueled with a hydrocarbon fuel using liquid oxygen as the primary oxidizer candidate. The primary concept for the pump turbine drive is pressure-fed catalyzed hydrogen peroxide. In order to control costs, the flight demonstration vehicle will be launched from a B-52 aircraft. The vehicle concept is based on the Air

  18. Controlled thermonuclear fusion; La fusion thermonucleaire controlee

    Energy Technology Data Exchange (ETDEWEB)

    Bobin, Jean-Louis


    This book presents, first, the basic nuclear physics and plasma physics principles at the origin of the researches on nuclear fusion which started in the 1950's. Then the magnetic and inertial confinement principles are described with their corresponding facilities: the tokamaks and the laser-induced inertial confinement fusion devices. After a brief outline of some exotic processes, the book describes some projects of thermonuclear power plants capable to supply electricity by the end of the 21. century. (J.S.)

  19. The apeNEXT project

    Energy Technology Data Exchange (ETDEWEB)

    Bodin, F. [IRISA/INRIA, Campus Universite de Beaulieu, Rennes (France); Boucaud, Ph. [LPT, University of Paris Sud, Orsay (France); Cabibbo, N. [INFN, Sezione di Rome (Italy); Di Carlo, F. [INFN, Sezione di Rome (Italy); De Pietri, R. [Physics Department, University of Parma and INFN, Gruppo Collegato di Parma (Italy); Di Renzo, F. [Physics Department, University of Parma and INFN, Gruppo Collegato di Parma (Italy); Errico, W. [INFN, di Pisa (Italy); Kaldass, H. [DESY Zeuthen (Germany); Lonardo, A. [INFN, Sezione di Rome (Italy); De Luca, S. [INFN, Sezione di Rome (Italy); Micheli, J. [LPT, University of Paris Sud, Orsay (France); Morenas, V. [LPC, Universite Blaise Pascal and IN2P3, Clermont (France); Pene, O. [LPT, University of Paris Sud, Orsay (France); Pleiter, D. [NIC/DESY Zeuthen (Germany); Paschedag, N. [DESY Zeuthen (Germany); Rapuano, F. [Physics Department, University of Milano-Bicocca (Italy); Rossetti, D. [INFN, Sezione di Rome (Italy); Sartori, L. [INFN, di Pisa (Italy); Schifano, F. [INFN, di Pisa (Italy); Simma, H. [DESY Zeuthen (Germany); Tripiccione, R. [Physics Deparment, University of Ferrara (Italy); Vicini, P. [INFN, Sezione di Rome (Italy)


    In this talk I report on the status of the apeNEXT project. apeNEXT is the last of a family of parallel computers designed, in a research environment, to provide multi-teraflops computing power to scientists involved in heavy numerical simulations. The architecture and the custom chip are optimized for Lattice QCD (LQCD) calculations but the favourable price performance ratio and the good efficiency for other kind of calculations make it a quite interesting tool for a large class of scientific problems.

  20. 2001 activity report of the development and research line in controlled thermonuclear fusion of the Plasma Associated Laboratory; Relatorio de atividades de 2001 da linha de pesquisa e desenvolvimento em fusao termonuclear controlada (fusao), do Laboratorio Associado de Plasma (LAP)

    Energy Technology Data Exchange (ETDEWEB)

    Ludwig, Gerson Otto


    The year 2001 activities of the controlled thermonuclear fusion research line of the Plasma Associated Laboratory at the National Institute for Space Research - Brazil are reported. The report approaches the staff, participation in congresses, goals for the year 2002 and papers on Tokamak plasmas, plasma diagnostic, bootstraps, plasma equilibrium and diagnostic.

  1. Evaluation of the cross-sections of threshold reactions leading to the production of long-lived radionuclides during irradiation of steels by thermonuclear spectrum neutrons

    CERN Document Server

    Blokhin, A I; Manokhin, V N; Mikhajlyukova, M V; Nasyrova, S M; Skripova, M V


    The present paper analyses and evaluates the cross-sections of threshold reactions leading to the production of long-lived radionuclides during the irradiation, by thermonuclear spectrum neutrons, of steels containing V, Ti, Cr, Fe and Ni. On the basis of empirical systematics. a new evaluation of the (n,2n), (n,p), (n,np), (n,alpha) and (n,n alpha) excitation functions is made for all isotopes of V, Ti, Cr, Fe and Ni and for intermediate isotopes produced in the chain from irradiated isotopes up to production of the long-lived radionuclides sup 3 sup 9 Ar, sup 4 sup 2 Ar, sup 4 sup 1 Ca, sup 5 sup 3 Mn, sup 6 sup 0 Fe, sup 6 sup 0 Co, sup 5 sup 9 Ni and sup 6 sup 3 Ni. A comparison is made with the experimental and other evaluated data.

  2. 2003 activity report of the development and research line in controlled thermonuclear fusion of the Plasma Associated Laboratory; Relatorio de atividades de 2003 da linha de pesquisa e desenvolvimento em fusao termonuclear controlada - fusao. Laboratorio Associado de Plasma (LAP)

    Energy Technology Data Exchange (ETDEWEB)

    Ludwig, Gerson Otto


    This document represents the 2003 activity report of the development and research line in controlled thermonuclear fusion of the Plasma Associated Laboratory - Brazil, approaching the areas of toroidal systems for magnetic confinement, plasma heating, current generation and high temperature plasma diagnostic.

  3. Research on the reactor physics and reactor safety of VVER reactors. AER Symposium 2016

    Energy Technology Data Exchange (ETDEWEB)

    Kliem, S.


    The selected paperscan be attributed to the following main subjects: Reactor start-up tests and use of corresponding data for code validation, code development and application, approaches for safety analyses, closure of nuclear fuel cycle, prospective reactor concepts.

  4. Error analysis for resonant thermonuclear reaction rates

    CERN Document Server

    Thompson, W J


    A detailed presentation is given of estimating uncertainties in thermonuclear reaction rates for stellar nucleosynthesis involving narrow resonances, starting from random errors in measured or calculated resonance and nuclear level properties. Special attention is given to statistical matters such as probability distributions, error propagation, and correlations between errors. Interpretation of resulting uncertainties in reaction rates and the distinction between symmetric and asymmetric errors are also discussed. Computing reaction rate uncertainties is described. We give examples from explosive nucleosynthesis by hydrogen burning on light nuclei.

  5. The apeNEXT project

    Energy Technology Data Exchange (ETDEWEB)

    Bodin, F.; Boucaud, P.; Cabibbo, N.; Calvayrac, F.; Della Morte, M.; De Pietri, R.; De Riso, P.; Di Carlo, F.; Di Renzo, F.; Errico, W.; Frezzotti, R.; Gensch, U.; Giorgino, T.; Guagnelli, M.; Herve, N.; Kaldass, H.; Lonardo, A.; Lukyanov, M.; Magazzu, G.; Micheli, J.; Morenas, V.; Mori, L.; Palombi, F.; Paschedag, N.; Pene, O.; Petronzio, R.; Pleiter, D.; Rapuano, F.; Rossetti, D.; Sartori, L.; Simma, H.; Schifano, F.; Tripiccione, R.; Vicini, P


    apeNEXT is a new generation APE processor, optimized for LGT simulations. The new project follows the basic ideas of previous APE machines and develops simple and cheap parallel systems with multi-Tflops processing power. This paper describes the main features of this new development.

  6. The Next Generation Science Standards (United States)

    Pruitt, Stephen L.


    The Next Generation Science Standards (NGSS Lead States 2013) were released almost two years ago. Work tied to the NGSS, their adoption, and implementation continues to move forward around the country. Stephen L. Pruitt, senior vice president, science, at Achieve, an independent, nonpartisan, nonprofit education reform organization that was a lead…

  7. School Foodservice: The Next Millennium. (United States)

    Fitzgerald, Patricia L.


    Examines trends identified in the American School Food Service Association's research-based "1998-2000 Strategic Plan." Forecasters are projecting that student enrollments will rise over the next five years, labor shortages will continue, competition from fast-food providers is increasing, food-service providers' roles are expanding, and…

  8. Computer Program of SIE ASME-NH Code for Structural Integrity Evaluation of Next Generation Reactors Subjecting to Elevated Temperature Operations

    Energy Technology Data Exchange (ETDEWEB)

    Koo, Gyeong Hoi; Lee, J. H


    In this report, the SIE ASME (Structural Integrity Evaluations by ASME-NH), which has a computerized implementation of ASME Pressure Vessels and Piping Code Section III Subsection NH rules, is developed to apply to the next generation reactor design subjecting to the elevated temperature operations over 500 .deg. C and over 30 years design lifetime, and the user's manual for this program is described in detail.

  9. Stabilized Spheromak Fusion Reactors

    Energy Technology Data Exchange (ETDEWEB)

    Fowler, T


    The U.S. fusion energy program is focused on research with the potential for studying plasmas at thermonuclear temperatures, currently epitomized by the tokamak-based International Thermonuclear Experimental Reactor (ITER) but also continuing exploratory work on other plasma confinement concepts. Among the latter is the spheromak pursued on the SSPX facility at LLNL. Experiments in SSPX using electrostatic current drive by coaxial guns have now demonstrated stable spheromaks with good heat confinement, if the plasma is maintained near a Taylor state, but the anticipated high current amplification by gun injection has not yet been achieved. In future experiments and reactors, creating and maintaining a stable spheromak configuration at high magnetic field strength may require auxiliary current drive using neutral beams or RF power. Here we show that neutral beam current drive soon to be explored on SSPX could yield a compact spheromak reactor with current drive efficiency comparable to that of steady state tokamaks. Thus, while more will be learned about electrostatic current drive in coming months, results already achieved in SSPX could point to a productive parallel development path pursuing auxiliary current drive, consistent with plans to install neutral beams on SSPX in the near future. Among possible outcomes, spheromak research could also yield pulsed fusion reactors at lower capital cost than any fusion concept yet proposed.

  10. An Analytical Method For The Solution Of Reactor Dynamic Equations

    African Journals Online (AJOL)

    In this paper, an analytical method for the solution of nuclear reactor dynamic equations is presented. The method is applied to a linearised high-order deterministic model of a pressurised water reactor plant driven by step-reactivity insertion. A comparison of this method with two other techniques (the matrix exponential and ...

  11. On Thermonuclear Reaction Rates


    Haubold, H. J.; Mathai, A. M.


    Nuclear reactions govern major aspects of the chemical evolution of galaxies and stars. Analytic study of the reaction rates and reaction probability integrals is attempted here. Exact expressions for the reaction rates and reaction probability integrals for nuclear reactions in the cases of nonresonant, modified nonresonant, screened nonresonant and resonant cases are given. These are expressed in terms of H-functions, G-functions and in computable series forms. Computational aspects are als...

  12. Is Silicene the Next Graphene?


    Voon, L. C. Lew Yan; Guzmán-Verri, G. G.


    This article reviews silicene, a relatively new allotrope of silicon, which can also be viewed as the silicon version of graphene. Graphene is a two-dimensional material with unique electronic properties qualitatively different from those of standard semiconductors such as silicon. While many other two-dimensional materials are now being studied, our focus here is solely on silicene. We first discuss its synthesis and the challenges presented. Next, a survey of some of its physical properties...

  13. Response of beryllium to severe thermal shocks -simulation of disruption and vertical displacement events in future thermonuclear devices

    Energy Technology Data Exchange (ETDEWEB)

    Linke, J.; Duwe, R.; Roedig, M.; Schuster, A. [Association Euratom-Forschungszentrum Juelich GmbH (Germany); Merola, M.; Qian, R.H.


    Beryllium will play an important role for plasma facing components in next step thermonuclear fusion devices such as ITER. In particular for the first wall beryllium will be used with an armor thickness of several millimeters. However, during plasma instabilities they will experience severe thermal shocks. Here plasma disruptions with deposited energy densities of several ten MJm{sup -2} are the most essential damaging mechanism. However, a signifant fraction of the incident energy will be absorbed by a dense cloud of ablation vapor, hence reducing the effective energy density at the beryllium surface to values in the order of 10 MJm{sup -2}. To investigate the material response to all these plasma instabilities thermal shock tests on small scale test coupons (disruption effects) and on actively cooled divertor modules (VDEs) have been performed in the electron beam test facility JUDITH at ITER relevant surface heat loads. These tests have been performed on different bulk beryllium grades and on plasma sprayed coatings; the influence of pulse duration, power density, and temperature effects has been investigated experimentally. Detailed in-situ diagnostics (for beam characterization, optical pyrometry etc.) and post mortem analyses (profilometry, metallography, optical and electron microscopy) have been applied to quantify the resulting material damage. 1D- and 2D models have developed to verify the experimental results obtained in the electron beam simulation experiments. (J.P.N.)

  14. Perspective on the next ten years in plasma physics

    Energy Technology Data Exchange (ETDEWEB)

    Killeen, J.


    A brief survey of developments in the plasma physics of magnetic fusion research is presented. The major experimental facilities of the next decade are listed. Eight fusion physics issues are identified which must be addressed as a complete plasma system in order to reach the goal of a fusion reactor. In order to resolve the physics issues the results from these new experimental facilities must be augmented by an extensive program of computer modeling. The use of computer models of a magnetically confined plasma and the implementation of these models on the new supercomputers of the next decade are the main topics of this paper.

  15. Performance and membrane fouling of a step-fed submerged membrane sequencing batch reactor treating swine biogas digestion slurry. (United States)

    Han, Zhiying; Chen, Shixia; Lin, Xiaochang; Yu, Hongjun; Duan, Li'an; Ye, Zhangying; Jia, Yanbo; Zhu, Songming; Liu, Dezhao


    To identify the performance of step-fed submerged membrane sequencing batch reactor (SMSBR) treating swine biogas digestion slurry and to explore the correlation between microbial metabolites and membrane fouling within this novel reactor, a lab-scale step-fed SMSBR was operated under nitrogen loading rate of 0.026, 0.052 and 0.062 g NH4(+)-N (gVSS·d)(-1). Results show that the total removal efficiencies for NH4(+)-N, total nitrogen and chemical oxygen demand in the reactor (>94%, >89% and >97%, respectively) were high during the whole experiment. However, the cycle removal efficiency of NH4(+)-N decreased significantly when the nitrogen loading rate was increased to 0.062 g NH4(+)-N (gVSS·d)(-1). The total removal efficiency of total phosphorus in the step-fed SMSBR was generally higher than 75%, though large fluctuations were observed during the experiments. In addition, the concentrations of microbial metabolites, i.e., soluble microbial products (SMP) and extracellular polymeric substances (EPS) from activated sludge increased as nitrogen loading rate increased, both showing quadratic equation correlations with viscosity of the mixed liquid in the step-fed SMSBR (both R(2) > 0.90). EPS content was higher than SMP content, while protein (PN) was detected as the main component in both SMP and EPS. EPS PN was found to be well correlated with transmembrane pressure, membrane flux and the total membrane fouling resistance. Furthermore, the three-dimensional excitation-emission matrix fluorescence spectroscopy results suggested the tryptophan-like protein as one of the main contributors to the membrane fouling. Overall, this study showed that the step-fed SMSBR could be used to treat swine digestion slurry at nitrogen loading rate of 0.052 g NH4(+)-N (gVSS·d)(-1), and the control strategy of membrane fouling should be developed based on reducing the tryptophan-like PN in EPS.


    Directory of Open Access Journals (Sweden)

    Darinka Korovljev


    Full Text Available Following the development of the powerful sport industry, in front of us appeared a lot of new opportunities for creating of the new programmes of exercising with certain requisites. One of such programmes is certainly step-aerobics. Step-aerobics can be defined as a type of aerobics consisting of the basic aerobic steps (basic steps applied in exercising on stepper (step bench, with a possibility to regulate its height. Step-aerobics itself can be divided into several groups, depending on the following: type of music, working methods and adopted knowledge of the attendants. In this work, the systematization of the basic steps in step-aerobics was made on the basis of the following criteria: steps origin, number of leg motions in stepping and relating the body support at the end of the step. Systematization of the basic steps of the step-aerobics is quite significant for making a concrete review of the existing basic steps, thus making creation of the step-aerobics lesson easier

  17. Imaging of high-energy x-ray emission from cryogenic thermonuclear fuel implosions on the NIF. (United States)

    Ma, T; Izumi, N; Tommasini, R; Bradley, D K; Bell, P; Cerjan, C J; Dixit, S; Döppner, T; Jones, O; Kline, J L; Kyrala, G; Landen, O L; LePape, S; Mackinnon, A J; Park, H-S; Patel, P K; Prasad, R R; Ralph, J; Regan, S P; Smalyuk, V A; Springer, P T; Suter, L; Town, R P J; Weber, S V; Glenzer, S H


    Accurately assessing and optimizing the implosion performance of inertial confinement fusion capsules is a crucial step to achieving ignition on the NIF. We have applied differential filtering (matched Ross filter pairs) to provide broadband time-integrated absolute x-ray self-emission images of the imploded core of cryogenic layered implosions. This diagnostic measures the temperature- and density-sensitive bremsstrahlung emission and provides estimates of hot spot mass, mix mass, and pressure.

  18. Safety assessment of in-vessel vapor explosion loads in next generation reactor

    Energy Technology Data Exchange (ETDEWEB)

    Bang, Kwang Hyun; Cho, Jong Rae; Choi, Byung Uk; Kim, Ki Yong; Lee, Kyung Jung [Korea Maritime University, Busan (Korea); Park, Ik Kyu [Seoul National University, Seoul (Korea)


    A safety assessment of the reactor vessel lower head integrity under in-vessel vapor explosion loads has been performed. The premixing and explosion calculations were performed using TRACER-II code. Using the calculated explosion pressures imposed on the lower head inner wall, strain calculations were performed using ANSYS code. The explosion analyses show that the explosion impulses are not altered significantly by the uncertain parameters of triggering location and time, fuel and vapor volume fractions in uniform premixture bounding calculations within the conservative ranges. Strain analyses using the calculated pressure loads on the lower head inner wall show that the vapor explosion-induced lower head failure is physically unreasonable. The static analysis using the conservative explosion-end pressure of 7,246 psia shows that the maximum equivalent strain is 4.3% at the bottom of lower head, which is less than the allowable threshold value of 11%. (author). 24 refs., 40 figs., 3 tabs.

  19. The two-nucleon system at next-to-next-to-next-to-leading order

    Energy Technology Data Exchange (ETDEWEB)

    Evgeny Epelbaum; Walter Gloeckle; Ulf-G. Meissner


    We consider the two-nucleon system at next-to-next-to-next-to-leading order (N{sup 3}LO) in chiral effective field theory. The two--nucleon potential at N{sup 3}LO consists of one-, two- and three-pion exchanges and a set of contact interactions with zero, two and four derivatives. In addition, one has to take into account various isospin--breaking and relativistic corrections. We employ spectral function regularization for the multi--pion exchanges. Within this framework, it is shown that the three-pion exchange contribution is negligibly small. The low--energy constants (LECs) related to pion-nucleon vertices are taken consistently from studies of pion-nucleon scattering in chiral perturbation theory. The total of 26 four--nucleon LECs has been determined by a combined fit to some np and pp phase shifts from the Nijmegen analysis together with the nn scattering length.

  20. Management and share of regulatory information through web; development of regulatory information management system for Korea next generation reactors

    Energy Technology Data Exchange (ETDEWEB)

    Lee, J. S.; Lee, J. H.; Jeong, Y. H.; Lee, S. H. [KINS, Taejon (Korea, Republic of); Yun, Y. C.; Park, M. I. [LG-EDS Systems, Seoul (Korea, Republic of)


    The Regulatory Information Management System developed by the Korea Institute of Nuclear Safety supports researchers who are in charge of developing SRRG for the Korea Next Generation Reactors, manage the developed SRRG and development process, and make it possible to share the SRRG information and background knowledge through the internet with the nuclear-related personnel and the public. From the experience of the system operation, the search engine is repalced to manage the native SRRG files directly. This change eliminates the inconsistency between native files and database files and improve the search exactness by automatic indexing function. The user interface of the internet homepage ( is completely rebuilded and allows SRRG developers to manage the search system and the atomic energy regulations database on the Web without the help of the client programs. General users are also able to utilize more convenient search function and additional information by the improved interface. The system is running under the backup system and firewall system for the data protection and security.

  1. Application of the Combined Reactors Method for Analysis of Steelmaking Process (United States)

    Lekakh, Simon N.; Robertson, D. G. C.

    A new integrated CFD-combined reactors approach is proposed for the description of processes in metallurgical vessels. CFD simulations were used to obtain the melt flow pattern in the vessels (ladle, tundish, and continuous caster mold). From these simulations, the characteristic curves were derived: (i) the residence time distribution curves (RTD) for flow-through systems (at tundish exit or at dendrite coherency surface in the mold) and (ii) the mixing curves for closed systems (ladle). In the next step, the melt flow was represented in a "combined reactors" system consisting of a combination of unit reactors (Plug Flow, Mixer, and Recirculated Volume). An inverse simulation was used to define the volumes of the reactor units and the melt flow rates between them by fitting to the characteristic curves from both methods (CFD and combined reactors). The suggested approach is demonstrated for multiple designs of Ar-stirred ladles, tundish, and SEN. This methodology can be used to enhance traditional post-processing CFD analysis and also as a tool for on-line process control.

  2. Neutron cross-sections for next generation reactors: New data from n_TOF

    CERN Document Server

    Colonna, N; Eleftheriadis, C; Leeb, H; Tain, J L; Calvino, F; Herrera-Martinez, A; Savvidis, I; Vlachoudis, V; Haas, B; Abbondanno, U; Vannini, G; Konovalov, V; Marques, L; Wiescher, M; de Albornoz, A Carrillo; Audouin, L; Mengoni, A; Quesada, J; Becvar, F; Plag, R; Cennini, P; Mosconi, M; Duran, I; Rauscher, T; Ketlerov, V; Couture, A; Capote, R; Sarchiapone, L; Pigni, M T; Vlastou, R; Domingo-Pardo, C; Pavlopoulos, P; Karamanis, D; Krticka, M; Jericha, E; Ferrari, A; Martinez, T; Oberhummer, H; Karadimos, D; Plompen, A; Isaev, S; Terlizzi, R; Kaeppeler, F; Cortes, G; Cox, J; Voss, F; Pretel, C; Berthoumieux, E; Dolfini, R; Vaz, P; Griesmayer, E; Heil, M; Lopes, I; Lampoudis, C; Walter, S; Calviani, M; Gonzalez-Romero, E; Stephan, C; Igashira, M; Papachristodoulou, C; Aerts, G; Tavora, L; Wendler, H; Milazzo, P M; Rudolf, G; Andrzejewski, J; Villamarin, D; Ferreira-Marques, R; O'Brien, S; Gunsing, F; Reifarth, R; Perrot, L; Lindote, A; Neves, F; Poch, A; Gramegna, F; Kerveno, M; Rubbia, C; Koehler, P; Dahlfors, M; Wisshak, K; Fujii, K; Salgado, J; Dridi, W; Ventura, A; Andriamonje, S; Dillman, I; Assimakopoulos, P; Ferrant, L; Lozano, M; Patronis, N; Chiaveri, E; Guerrero, C; Kadi, Y; Baumann, P; Moreau, C; Oshima, M; Rullhusen, P; Furman, W; David, S; Marrone, S; Paradela, C; Vicente, M C; Tassan-Got, L; Cano-Ott, D; Alvarez-Velarde, F; Massimi, C; Mastinu, P; Pancin, J; Papadopoulos, C; Tagliente, G; Alvarez, H; Haight, R; Goverdovski, A; Chepel, V; Rosetti, M; Kossionides, E; Badurek, G; Marganiec, J; Lukic, S; Frais-Koelbl, H; Pavlik, A; Goncalves, I


    In 2002, an innovative neutron time-of-flight facility started operation at CERN: n\\_TOF. The main characteristics that make the new facility unique are the high instantaneous neutron flux, high resolution and wide energy range. Combined with state-of-the-art detectors and data acquisition system, these features have allowed to collect high accuracy neutron cross-section data on a variety of isotopes, many of which radioactive, of interest for Nuclear Astrophysics and for applications to advanced reactor technologies. A review of the most important results on capture and fission reactions obtained so far at n\\_TOF is presented, together with plans for new measurements related to nuclear industry. (C) 2010 Elsevier Ltd. All rights reserved.

  3. Neutron cross-sections for next generation reactors: new data from n_TOF. (United States)

    Colonna, N; Abbondanno, U; Aerts, G; Alvarez, H; Alvarez-Velarde, F; Andriamonje, S; Andrzejewski, J; Assimakopoulos, P; Audouin, L; Badurek, G; Baumann, P; Becvar, F; Berthoumieux, E; Calviani, M; Calviño, F; Cano-Ott, D; Capote, R; de Albornoz, A Carrillo; Cennini, P; Chepel, V; Chiaveri, E; Cortes, G; Couture, A; Cox, J; Dahlfors, M; David, S; Dillman, I; Dolfini, R; Domingo-Pardo, C; Dridi, W; Duran, I; Eleftheriadis, C; Ferrant, L; Ferrari, A; Ferreira-Marques, R; Frais-Koelbl, H; Fujii, K; Furman, W; Goncalves, I; González-Romero, E; Goverdovski, A; Gramegna, F; Griesmayer, E; Guerrero, C; Gunsing, F; Haas, B; Haight, R; Heil, M; Herrera-Martinez, A; Igashira, M; Isaev, S; Jericha, E; Käppeler, F; Kadi, Y; Karadimos, D; Karamanis, D; Kerveno, M; Ketlerov, V; Koehler, P; Konovalov, V; Kossionides, E; Krticka, M; Lampoudis, C; Leeb, H; Lindote, A; Lopes, I; Lozano, M; Lukic, S; Marganiec, J; Marques, L; Marrone, S; Martínez, T; Massimi, C; Mastinu, P; Mengoni, A; Milazzo, P M; Moreau, C; Mosconi, M; Neves, F; Oberhummer, H; O'Brien, S; Oshima, M; Pancin, J; Papachristodoulou, C; Papadopoulos, C; Paradela, C; Patronis, N; Pavlik, A; Pavlopoulos, P; Perrot, L; Pigni, M T; Plag, R; Plompen, A; Plukis, A; Poch, A; Pretel, C; Quesada, J; Rauscher, T; Reifarth, R; Rosetti, M; Rubbia, C; Rudolf, G; Rullhusen, P; Salgado, J; Sarchiapone, L; Savvidis, I; Stephan, C; Tagliente, G; Tain, J L; Tassan-Got, L; Tavora, L; Terlizzi, R; Vannini, G; Vaz, P; Ventura, A; Villamarin, D; Vicente, M C; Vlachoudis, V; Vlastou, R; Voss, F; Walter, S; Wendler, H; Wiescher, M; Wisshak, K


    In 2002, an innovative neutron time-of-flight facility started operation at CERN: n_TOF. The main characteristics that make the new facility unique are the high instantaneous neutron flux, high resolution and wide energy range. Combined with state-of-the-art detectors and data acquisition system, these features have allowed to collect high accuracy neutron cross-section data on a variety of isotopes, many of which radioactive, of interest for Nuclear Astrophysics and for applications to advanced reactor technologies. A review of the most important results on capture and fission reactions obtained so far at n_TOF is presented, together with plans for new measurements related to nuclear industry. Copyright 2010 Elsevier Ltd. All rights reserved.

  4. Relativistic outflow from two thermonuclear shell flashes on neutron stars

    NARCIS (Netherlands)

    in 't Zand, J.J.M.; Keek, L.; Cavecchi, Y.


    We study the exceptionally short (32-43 ms) precursors of two intermediate-duration thermonuclear X-ray bursts observed with the Rossi X-ray Timing Explorer from the neutron stars in 4U 0614+09 and 2S 0918-549. They exhibit photon fluxes that surpass those at the Eddington limit later in the burst

  5. Compact fusion reactors

    CERN Multimedia

    CERN. Geneva


    Fusion research is currently to a large extent focused on tokamak (ITER) and inertial confinement (NIF) research. In addition to these large international or national efforts there are private companies performing fusion research using much smaller devices than ITER or NIF. The attempt to achieve fusion energy production through relatively small and compact devices compared to tokamaks decreases the costs and building time of the reactors and this has allowed some private companies to enter the field, like EMC2, General Fusion, Helion Energy, Lawrenceville Plasma Physics and Lockheed Martin. Some of these companies are trying to demonstrate net energy production within the next few years. If they are successful their next step is to attempt to commercialize their technology. In this presentation an overview of compact fusion reactor concepts is given.

  6. Study on the License Requirements for the SRO/RO of the Kijang Research Reactor

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Subeom; Shin, Taemyung [Korea Nat. University of Transportation, Seoul (Korea, Republic of); Chae, H. T.; Ahn, G. H. [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of); Kim, S. J.; Gam, S. C. [Korea Institute of Nuclear Safety, Daejeon (Korea, Republic of)


    The purpose of the study is to propose an appropriate regulatory position for the Kijang reactor operator license requirement by the review of the applicability and compatibility of HANARO SRO/RO license holders for Kijang reactor operation. As the area using radioactive isotope became gradually enlarged both inside and outside of the country, the Kijang research reactor is planned and now under construction next to the HANARO research reactor now being operated in Taejon. In this paper, therefore, an establishment of revised operator license system is discussed for the new research reactor. The design and operation characteristics of the two (HANARO and Kijang) reactors are concluded to be very similar to each other, however, there still exist slight differences in some minor portions. It is recommendable to allow an independent license for each reactor if two reactors of the same power level have recognizable differences in the design and operation characteristics.

  7. Report made on behalf of the commission of foreign affairs about the project of law, adopted by the Senate, giving permission to the approval of the agreement between the French government and the international organization for thermonuclear fusion energy ITER, relative to the head office of ITER organization and to the privileges and immunities of ITER organization in the French territory; Rapport fait au nom de la commission des affaires etrangeres sur le projet de loi, adopte par le senat, autorisant l'approbation de l'accord entre le Gouvernement de la Republique francaise et l'Organisation internationale ITER pour l'energie de fusion relatif au siege de l'Organisation ITER et aux privileges et immunites de l'Organisation ITER sur le territoire francais

    Energy Technology Data Exchange (ETDEWEB)



    The will of building up an international thermonuclear experimental reactor (ITER) gathers since several years the European community of atomic energy (Euratom), Japan, the USA, and Russia, next followed by China, South Korea and, since 2005, by India. The agreement signed in Paris between these seven parties on November 21, 2006 entrusted the international organization ITER with the realization of this project. The implications of the ITER project are enormous both in their scientific and in their economical aspects. France has a particular position in this project since the head office of ITER organisation is sited at Saint-Paul-lez-Durance and the tokamak will be built at Cadarache. Therefore, an agreement has been signed between ITER organization and the French government. The approval of this agreement is the object of this project of law. The document presents first the principle, challenge and stakes of the ITER project and the long negotiations that have led to chose France for the setting up of the research facility. Then, it presents the agreement of November 7, 2007, which fixes the general framework of the conditions necessary to the achievement of the project. The agreement comprises the classical rules, privileges and immunities of any international organization sited on the French ground, plus some more specific dispositions in particular in the domain of management of the wastes generated by the facility. (J.S.)

  8. Department of Thermonuclear Research annual report 1990

    Energy Technology Data Exchange (ETDEWEB)

    Sadowski, M. [ed.


    Department of Thermonuclear Research Annual Report 1990 presents the most important results of theoretical, experimental, and technological studies, carried out within a framework of two programs: Diagnostics of High-Temperature Plasma (CPBP 01.10) and Nuclear Technology (CPBR 5.8). Theoretical studies of tokamak edge plasmas, charged particle motions, strong refraction effects, current pulse generators, classical models of atomic collisions, and electron mechanisms of the Coulomb barrier tunneling, are shortly summarized. Experimental studies of X-ray, ion, and proton emission from the RPI-type devices, as well as optimization tests and electron beam measurements at the PF-type facilities, are described. Technological studies of opto-electronic transmission systems, modifications of diagnostic equipment, design and construction of new PF facilities, as well as applications of the IONOTRON-type devices, are also presented. (author). 56 refs, 20 figs.

  9. 2D simulations of the double-detonation model for thermonuclear transients from low-mass carbon-oxygen white dwarfs (United States)

    Sim, S. A.; Fink, M.; Kromer, M.; Röpke, F. K.; Ruiter, A. J.; Hillebrandt, W.


    Thermonuclear explosions may arise in binary star systems in which a carbon-oxygen (CO) white dwarf (WD) accretes helium-rich material from a companion star. If the accretion rate allows a sufficiently large mass of helium to accumulate prior to ignition of nuclear burning, the helium surface layer may detonate, giving rise to an astrophysical transient. Detonation of the accreted helium layer generates shock waves that propagate into the underlying CO WD. This might directly ignite a detonation of the CO WD at its surface (an edge-lit secondary detonation) or compress the core of the WD sufficiently to trigger a CO detonation near the centre. If either of these ignition mechanisms works, the two detonations (helium and CO) can then release sufficient energy to completely unbind the WD. These 'double-detonation' scenarios for thermonuclear explosion of WDs have previously been investigated as a potential channel for the production of Type Ia supernovae from WDs of ˜ 1 M⊙. Here we extend our 2D studies of the double-detonation model to significantly less massive CO WDs, the explosion of which could produce fainter, more rapidly evolving transients. We investigate the feasibility of triggering a secondary core detonation by shock convergence in low-mass CO WDs and the observable consequences of such a detonation. Our results suggest that core detonation is probable, even for the lowest CO core masses that are likely to be realized in nature. To quantify the observable signatures of core detonation, we compute spectra and light curves for models in which either an edge-lit or compression-triggered CO detonation is assumed to occur. We compare these to synthetic observables for models in which no CO detonation was allowed to occur. If significant shock compression of the CO WD occurs prior to detonation, explosion of the CO WD can produce a sufficiently large mass of radioactive iron-group nuclei to significantly affect the light curves. In particular, this can lead

  10. The Next Generation Space Telescope (United States)

    Bely, Pierre-Yves (Editor); Burrows,, Christopher J. (Editor); Illingworth,, Garth D.


    In Space Science in the Twenty-First Century, the Space Science Board of the National Research Council identified high-resolution-interferometry and high-throughput instruments as the imperative new initiatives for NASA in astronomy for the two decades spanning 1995 to 2015. In the optical range, the study recommended an 8 to 16-meter space telescope, destined to be the successor of the Hubble Space Telescope (HST), and to complement the ground-based 8 to 10-meter-class telescopes presently under construction. It might seem too early to start planning for a successor to HST. In fact, we are late. The lead time for such major missions is typically 25 years, and HST has been in the making even longer with its inception dating back to the early 1960s. The maturity of space technology and a more substantial technological base may lead to a shorter time scale for the development of the Next Generation Space Telescope (NGST). Optimistically, one could therefore anticipate that NGST be flown as early as 2010. On the other hand, the planned lifetime of HST is 15 years. So, even under the best circumstances, there will be a five year gap between the end of HST and the start of NGST. The purpose of this first workshop dedicated to NGST was to survey its scientific potential and technical challenges. The three-day meeting brought together 130 astronomers and engineers from government, industry and universities. Participants explored the technologies needed for building and operating the observatory, reviewed the current status and future prospects for astronomical instrumentation, and discussed the launch and space support capabilities likely to be available in the next decade. To focus discussion, the invited speakers were asked to base their presentations on two nominal concepts, a 10-meter telescope in space in high earth orbit, and a 16-meter telescope on the moon. The workshop closed with a panel discussion focused mainly on the scientific case, siting, and the

  11. Pulsating Instability of Turbulent Thermonuclear Flames in Type Ia Supernovae (United States)

    Poludnenko, Alexei Y.


    Presently, one of the main explosion scenarios of type Ia supernovae (SNIa), aimed at explaining both "normal" and subluminous events, is the thermonuclear incineration of a white-dwarf in a single-degenerate system. The underlying engine of such explosions is the turbulent thermonuclear flame. Modern, large-scale, multidimensional simulations of SNIa cannot resolve the internal flame structure, and instead must include a subgrid-scale prescription for the turbulent-flame properties. As a result, development of robust, parameter-free, large-scale models of SNIa crucially relies on the detailed understanding of the turbulent flame properties during each stage of the flame evolution. Due to the complexity of the flame dynamics, such understanding must be validated by the first-principles direct numerical simulations (DNS). In our previous work, we showed that sufficiently fast turbulent flames are inherently susceptible to the development of detonations, which may provide the mechanism for the deflagration-to-detonation transition (DDT) in the delayed-detonation model of SNIa. Here we extend this study by performing detailed analysis of the turbulent flame properties at turbulent intensities below the critical threshold for DDT. We carried out a suite of 3D DNS of turbulent flames for a broad range of turbulent intensities and system sizes using a simplified, single-step, Arrhenius-type reaction kinetics. Our results show that at the later stages of the explosion, as the turbulence intensity increases prior to the possible onset of DDT, the flame front will become violently unstable. We find that the burning rate exhibits periodic pulsations with the energy release rate varying by almost an order of magnitude. Furthermore, such flame pulsations can produce pressure waves and shocks as the flame speed approaches the critical Chapman-Jouguet deflagration speed. Finally, in contrast with the current theoretical understanding, such fast turbulent flames can propagate at

  12. An overview of the Daya Bay Reactor Neutrino Experiment

    CERN Document Server

    Cao, Jun


    The Daya Bay Reactor Neutrino Experiment discovered an unexpectedly large neutrino oscillation related to the mixing angle $\\theta_{13}$ in 2012. This finding paved the way to the next generation of neutrino oscillation experiments. In this article, we review the history, featured design, and scientific results of Daya Bay. Prospects of the experiment are also described.

  13. An overview of the Daya Bay reactor neutrino experiment


    Cao, Jun; Luk, Kam-Biu


    The Daya Bay Reactor Neutrino Experiment discovered an unexpectedly large neutrino oscillation related to the mixing angle $\\theta_{13}$ in 2012. This finding paved the way to the next generation of neutrino oscillation experiments. In this article, we review the history, featured design, and scientific results of Daya Bay. Prospects of the experiment are also described.

  14. The Next Generation Science Standards: The Features and Challenges (United States)

    Pruitt, Stephen L.


    Beginning in January of 2010, the Carnegie Corporation of New York funded a two-step process to develop a new set of state developed science standards intended to prepare students for college and career readiness in science. These new internationally benchmarked science standards, the Next Generation Science Standards (NGSS) were completed in…

  15. Plutonium Recycle: The Fateful Step (United States)

    Speth, J. Gustave; And Others


    Calls attention to the fact that if the Atomic Energy Commission proceeds with its plans to authorize the nuclear power industry to use plutonium as a fuel in commercial nuclear reactors around the country, this will result in a dramatic escalation in the risks posed by nuclear power. (PEB)

  16. Linear coupling dependence on intensity and a next step towards a feedback (MD1850)

    CERN Document Server

    Persson, Tobias Hakan Bjorn; Coello De Portugal - Martinez Vazquez, Jaime Maria; Gasior, Marek; Giovannozzi, Massimo; Olexa, Jakub; Tomas Garcia, Rogelio; Garcia-Tabares Valdivieso, Ana; Valuch, Daniel


    Transverse coupling has proven to be an important variable to control beam dynamics and performance in the LHC. In this report, we present the first measurement of transverse coupling vs beam intensity. The analysis shows no dependency within the experimental uncertainties. This study was made possible with the new implementation of an AC-dipole-like excitation using the ADT. It provides the functionality to excite a single bunch in a train. The demonstration of this functionality is also an important step towards creating an automatic coupling correction tool for the LHC. Transverse coupling has been observed to vary with time at injection. In this report, a quantitative measurement of the coupling as a function of time after ramp-down is presented. Turn-by-turn data was also acquired to compare the performance of the new DOROS system to the standard BPMs.

  17. Defining excellence: next steps for practicing clinicians seeking to prevent diagnostic error. (United States)

    Foster, Paul N; Klein, Julie R


    The Institute of Medicine (IOM) released its report on diagnostic errors in September, 2015. The report highlights the urgency of reducing errors and calls for system-level intervention and changes in our basic clinical interactions. Using the report's controversial definition of diagnostic error as a starting point, we introduce the issues and the potential impact on practicing physicians. We report a case used to illustrate this in an academic conference. Finally, we turn to the challenge of integrating these ideas into the traditional peer-review process. We argue that the medical community must evolve from understanding diagnostic failures to redesigning the diagnostic process. We should see errors as steps toward diagnostic excellence and reliable processes that minimize the risk of mislabeling and harm.

  18. Defining excellence: next steps for practicing clinicians seeking to prevent diagnostic error

    Directory of Open Access Journals (Sweden)

    Paul N. Foster


    Full Text Available The Institute of Medicine (IOM released its report on diagnostic errors in September, 2015. The report highlights the urgency of reducing errors and calls for system-level intervention and changes in our basic clinical interactions. Using the report’s controversial definition of diagnostic error as a starting point, we introduce the issues and the potential impact on practicing physicians. We report a case used to illustrate this in an academic conference. Finally, we turn to the challenge of integrating these ideas into the traditional peer-review process. We argue that the medical community must evolve from understanding diagnostic failures to redesigning the diagnostic process. We should see errors as steps toward diagnostic excellence and reliable processes that minimize the risk of mislabeling and harm.

  19. Shear-Wave Splitting in a Critical Crust: the Next Step Biréfringence des ondes transversales dans les croûtes critiques : la prochaine étape

    Directory of Open Access Journals (Sweden)

    Crampin S.


    -organized criticality. The next step is to employ these techniques to model, monitor, and predict the effects of changing conditions on the deformation of the rockmass. On pourrait avancer que l'anisotropie dans la biréfringence des ondes transversales n'a pas répondu à ses promesses initiales, à savoir ouvrir une nouvelle voie dans la compréhension des phénomènes de fissures et de contraintes dans la croûte terrestre. Dans cet article sont présentés deux développements révélés récemment, qui paraissent raviver ces premiers espoirs et apportent des opportunités nouvelles pour le contrôle, la modélisation et même la prévision des déformations (avant fracture dans les roches microfracturées et saturées de fluides. Ainsi, un modèle de poroélasticité (APE développé récemment concerne l'évolution sous contraintes des roches microfracturées et saturées en fluide et reproduit une large gamme de phénomènes, qui seraient autrement inexpliqués ou dissociés, et semble être une bonne approximation au premier ordre de l'évolution des roches microfracturées et saturées en fluide. Puisque les paramètres qui contrôlent à petite échelle la déformation (avant fracture contrôlent aussi la biréfringence des ondes transversales, il apparaît que l'évolution des roches microfracturées et saturées peut être aussi directement contrôlée par cette biréfringence et que la réponse à des changements futurs peut être prédite par l'APE. Le bon usage de la modélisation de l'APE et des observations de la biréfringence des ondes transversales implique que la plupart des roches soient proches d'un stade de fracturation critique associé à une percolation limite, situation où la résistance aux contraintes transversales disparaît et où les fractures transversales peuvent se propager. Ceci corrobore une autre hypothèse concernant la mise en situation critique spontanée des roches in situ. La conséquence de cette identification est que la physique à petite

  20. Building the Next Bioethics Commission. (United States)

    Capron, Alexander M


    At every moment, somewhere in the world, a group of men and women are sitting around a table deliberating about an ethical issue posed by medicine and research, whether as a research ethics committee; a hospital or clinical ethics committee; a stem-cell review committee; a gene transfer research committee; a biobank ethics committee; an ethics advisory committee for a medical or nursing association or nongovernmental organization; a state, provincial, national, or intergovernmental bioethics committee; or an ad hoc panel examining a particular development or case. However, the last national committee in the United States, the Presidential Commission for the Study of Bioethical Issues, held its final meeting at the end of August 2016 and closed its doors. Should we regret its departure? I believe that the United States would benefit from having another national bioethics advisory body, but I do not think that the commission should simply have continued under a new president in the same form. Instead, looking at the experience of that commission and its six predecessors-who they were, how they worked, the functions they served, and the problems they experienced-we can derive some useful ideas for anyone planning to build the next commission. © 2017 The Hastings Center.

  1. CERN The next 50 years

    CERN Document Server

    Maiani, Luciano


    The Large Hadron Collider (LHC) from CERN is a 14 TeV proton-proton collider that is at the cutting edge of technology, and is a heartening sign of both the public's support for basic science in Europe and beyond, and the determination of European countries to stay at the forefront of particle physics. Realization of this project started some 50 years ago. Now for the next 50 years, particle phycists not only at CERN are planning a new generation of experiments that will push the high-energy boundary back even further. At CERN, a high-energy electron-positron linear collider, such as the 3-5 TeV Compact Linear Collider (CLIC) project is being considered. At Fermilab, focus is on a Very Large Hadron Collider (VLHC) that would take physicists into the 200 TeV region. These two possibilities could be among the long-term goals of the global accelerator network, which would keep the world's particle physicists busy until 2050.

  2. ISECG Mission Scenarios and Their Role in Informing Next Steps for Human Exploration Beyond Low Earth Orbit (United States)

    Culbert, Christopher J.; Mongrard, Olivier; Satoh, Naoki; Goodliff, Kandyce; Seaman, Calvin H.; Troutman, Patrick; Martin, Eric


    The International Space Exploration Coordination Group (ISECG) was established in response to The Global Exploration Strategy (GES): The Framework for Coordination developed by fourteen space agencies* and released in May 2007. This GES Framework Document recognizes that preparing for human space exploration is a stepwise process, starting with basic knowledge and culminating in a sustained human presence in deep space. ISECG has developed several optional global exploration mission scenarios enabling the phased transition from human operations in Low Earth Orbit (LEO) and utilization of the International Space Station (ISS) to human missions beyond LEO leading ultimately to human missions to cis-lunar space, the Moon, Near Earth Asteroids, Mars and its environs. Mission scenarios provide the opportunity for judging various exploration approaches in a manner consistent with agreed international goals and strategies. Each ISECG notional mission scenario reflects a series of coordinated human and robotic exploration missions over a 25-year horizon. Mission scenarios are intended to provide insights into next steps for agency investments, following on the success of the ISS. They also provide a framework for advancing the definition of Design Reference Missions (DRMs) and the concepts for capabilities contained within. Each of the human missions contained in the scenarios has been characterized by a DRM which is a top level definition of mission sequence and the capabilities needed to execute that mission. While DRMs are generally destination focused, they will comprise capabilities which are reused or evolved from capabilities used at other destinations. In this way, an evolutionary approach to developing a robust set of capabilities to sustainably explore our solar system is defined. Agencies also recognize that jointly planning for our next steps, building on the accomplishments of ISS, is important to ensuring the robustness and sustainability of any human

  3. EDITORIAL: The next photonic revolution The next photonic revolution (United States)

    Zheludev, Nikolay I.


    This special section on Nanophotonics and Metamaterials is a follow-up to the second European Topical Meeting of the NANOMETA series of meetings (see which took place on 5-8 January 2009, in Seefeld, Austria. The main idea of the first NANOMETA meeting held in 2007 was to bring together the mature community of microwave electrical engineers with the emerging community of photonics researchers interested in the physics of light coupled to nanostructures. In recent years the research landscape has shifted dramatically. A wider proliferation of nanofabrication techniques such as electron beam lithography, nanoimprint and focused ion beam milling, diagnostics techniques such as near-field scanning imaging, cathodoluminescence with nanoscale resolution and micro-spectrometry, and the availability of affordable broadband and ultrafast optical sources, have moved the research focus of the NANOMETA community to the optical domain. Quite naturally the ideas of the nonlinearity of materials and the coherency of light in the nanoscale realm have been widely discussed. Driven by the dream of untapped device and material functionality, nonlinear and switchable nanophotonic devices and photonic metamaterials, along with the concept of tailoring the electromagnetic space with metamaterials, appear to be the main avenues along which the subject will develop in the coming years. Indeed, in the last 20 years photonics has played a key role in creating the world as we know it, with enormous beneficial social impact worldwide. It is impossible to imagine modern society without the globe-spanning broadband internet and mobile telephony made possible by the implementation of optical fibre core networks, optical disc data storage (underpinned by the development of compact semiconductor lasers), modern image display technologies and laser-assisted manufacturing. We now anticipate that the next photonic revolution will continue to grow, explosively fuelled by a new

  4. Repairing liner of the reactor; Reparacion del liner del reactor

    Energy Technology Data Exchange (ETDEWEB)

    Aguilar H, F. [ININ, 52045 Ocoyoacac, Estado de Mexico (Mexico)


    Due to the corrosion problems of the aluminum coating of the reactor pool, a periodic inspections program by ultrasound to evaluate the advance grade and the corrosion speed was settled down. This inspections have shown the necessity to repair some areas, in those that the slimming is significant, of not making it can arrive to the water escape of the reactor pool. The objective of the repair is to place patches of plates of 1/4 inch aluminum thickness in the areas of the reactor 'liner', in those that it has been detected by ultrasound a smaller thickness or similar to 3 mm. To carry out this the fuels are move (of the core and those that are decaying) to a temporary storage, the structure of the core is confined in a tank that this placed inside the pool of the reactor, a shield is placed in the thermal column and it is completely extracted the water for to leave uncover the 'liner' of the reactor. (Author)

  5. Fusion Reactor Materials semiannual progress report for period ending September 30, 1991

    Energy Technology Data Exchange (ETDEWEB)



    This report contains papers on topic in the following areas of thermonuclear reactor materials: irradiation facilities, test matrices, and experimental methods; dosimetry, damage parameters and activation calculations; materials engineering and design requirements; fundamental mechanical behavior; radiation effects; development of structural alloys; solid breeding materials and beryllium; and ceramics. These paper have been index separately elsewhere. (LSP).

  6. Monte Carlo simulations of the SLOWPOKE-2 reactor

    Energy Technology Data Exchange (ETDEWEB)

    Tan, A.; Buijs, A., E-mail:, E-mail: [McMaster University, Hamilton, ON (Canada)


    The goal of this project is to study the transient behaviour of the SLOWPOKE-2 reactor using Monte-Carlo simulations. By validating the Monte-Carlo methods in G4-STORK with experimental measurements we hope to extend our understanding of reactor transients as well as further develop our methods to model the transients of the next generation reactor designs. A SLOWPOKE-2 reactor such as the one at RMC is modelled using simulation tools from GEANT4 and data taken from open literature. Simulations in G4-STORK find a neutron flux of order 10{sup 12} n cm{sup -2} s{sup -1} and a control rod worth of (4.9 2.0) mk compared to the experimentally measured worth of 5.45 mk. (author)

  7. Incentivising innovation in antibiotic drug discovery and development: progress, challenges and next steps. (United States)

    Simpkin, Victoria L; Renwick, Matthew J; Kelly, Ruth; Mossialos, Elias


    Political momentum and funding for combatting antimicrobial resistance (AMR) continues to build. Numerous major international and national initiatives aimed at financially incentivising the research and development (R&D) of antibiotics have been implemented. However, it remains unclear how to effectively strengthen the current set of incentive programmes to further accelerate antibiotic innovation. Based on a literature review and expert input, this study first identifies and assesses the major international, European Union, US and UK antibiotic R&D funding programmes. These programmes are then evaluated across market and public health criteria necessary for comprehensively improving the antibiotic market. The current set of incentive programmes are an important initial step to improving the economic feasibility of antibiotic development. However, there appears to be a lack of global coordination across all initiatives, which risks duplicating efforts, leaving funding gaps in the value chain and overlooking important AMR goals. This study finds that incentive programmes are overly committed to early-stage push funding of basic science and preclinical research, while there is limited late-stage push funding of clinical development. Moreover, there are almost no pull incentives to facilitate transition of antibiotic products from early clinical phases to commercialisation, focus developer concentration on the highest priority antibiotics and attract large pharmaceutical companies to invest in the market. Finally, it seems that antibiotic sustainability and patient access requirements are poorly integrated into the array of incentive mechanisms.The Journal of Antibiotics advance online publication, 1 November 2017; doi:10.1038/ja.2017.124.

  8. Galvanizing action: conclusions and next steps for mainstreaming zinc interventions in public health programs. (United States)

    Brown, Kenneth H; Baker, Shawn K


    This paper summarizes the results of the foregoing reviews of the impact of different intervention strategies designed to enhance zinc nutrition, including supplementation, fortification, and dietary diversification or modification. Current evidence indicates a beneficial impact of such interventions on zinc status and zinc-related functional outcomes. Preventive zinc supplementation reduces the incidence of diarrhea and acute lower respiratory tract infection among young children, decreases mortality of children over 12 months of age, and increases growth velocity. Therapeutic zinc supplementation during episodes of diarrhea reduces the duration and severity of illness. Zinc fortification increases zinc intake and total absorbed zinc, and recent studies are beginning to confirm a positive impact of zinc fortification on indicators of population zinc status. To assist with the development of zinc intervention programs, more information is needed on the prevalence of zinc deficiency in different countries, and rigorous evaluations of the effectiveness of large-scale zinc intervention programs should be planned. Recommended steps for scaling up zinc intervention programs, with or without other micronutrients, are described. In summary, there is now clear evidence of the benefit of selected interventions to reduce the risk of zinc deficiency, and a global commitment is urgently needed to conduct systematic assessments of population zinc status and to develop interventions to control zinc deficiency in the context of existing public health and nutrition programs.

  9. Nuclear Safeguards Considerations For The Pebble Bed Modular Reactor (PBMR)

    Energy Technology Data Exchange (ETDEWEB)

    Phillip Casey Durst; David Beddingfield; Brian Boyer; Robert Bean; Michael Collins; Michael Ehinger; David Hanks; David L. Moses; Lee Refalo


    High temperature reactors (HTRs) have been considered since the 1940s, and have been constructed and demonstrated in the United Kingdom (Dragon), United States (Peach Bottom and Fort Saint Vrain), Japan (HTTR), Germany (AVR and THTR-300), and have been the subject of conceptual studies in Russia (VGM). The attraction to these reactors is that they can use a variety of reactor fuels, including abundant thorium, which upon reprocessing of the spent fuel can produce fissile U-233. Hence, they could extend the stocks of available uranium, provided the fuel is reprocessed. Another attractive attribute is that HTRs typically operate at a much higher temperature than conventional light water reactors (LWRs), because of the use of pyrolytic carbon and silicon carbide coated (TRISO) fuel particles embedded in ceramic graphite. Rather than simply discharge most of the unused heat from the working fluid in the power plant to the environment, engineers have been designing reactors for 40 years to recover this heat and make it available for district heating or chemical conversion plants. Demonstrating high-temperature nuclear energy conversion was the purpose behind Fort Saint Vrain in the United States, THTR-300 in Germany, HTTR in Japan, and HTR-10 and HTR-PM, being built in China. This resulted in nuclear reactors at least 30% or more thermodynamically efficient than conventional LWRs, especially if the waste heat can be effectively utilized in chemical processing plants. A modern variant of high temperature reactors is the Pebble Bed Modular Reactor (PBMR). Originally developed in the United States and Germany, it is now being redesigned and marketed by the Republic of South Africa and China. The team examined historical high temperature and high temperature gas reactors (HTR and HTGR) and reviewed safeguards considerations for this reactor. The following is a preliminary report on this topic prepared under the ASA-100 Advanced Safeguards Project in support of the NNSA Next

  10. Joint KAERI/VAEC pre-possibility study on a new research reactor for Vietnam

    Energy Technology Data Exchange (ETDEWEB)

    Park, Cheol; Lee, B. C.; Chae, H. T.; Kim, H.; Lee, C. S.; Choi, C. O.; Jun, B. J. [KAERI, Taejon (Korea, Republic of); Vien, Luong Ba; Dien, Nguyen Nhi [Vietnam Atomic Energy Commission, Hanoi (Viet Nam)


    Based on the agreement on the technical cooperation for nuclear technology between Korea and Vietnam, a KAERI/VAEC joint study on the pre-possibility of a new research reactor for Vietnam has been carried out in the research reactor area from Nov. 2003 to May 2004. In this report, the results of the pre-possibility study on a new research reactor are described. The report presents the necessity of a new research reactor in Vietnam, and the desired performance requirements of the new research reactor if necessary. The major design characteristics of some existing research reactors and those under planning were also reviewed and the main characteristics which should be considered in selecting a new multipurpose research reactor for Vietnam were drawn. Some recommendations on the considerations for the next step of the feasibility study such as the project formulation, manpower requirements and international co-operation were also briefly touched upon.

  11. Status of the apeNEXT project

    CERN Document Server

    Ammendola, R.; Boucaud, Philippe; Cabibbo, N.; Di Carlo, F.; De Pietri, R.; Di Renzo, F.; Errico, W.; Fucci, A.; Guagnelli, M.; Kaldass, H.; Lonardo, A.; de Luca, S.; Micheli, J.; Morenas, V.; Pene, O.; Petronzio, R.; Palombi, F.; Pleiter, D.; Paschedag, N.; Rapuano, F.; De Riso, P.; Rossetti, D.; Salamon, A.; Salina, G.; Sartori, L.; Schifano, F.; Simma, H.; Tripiccione, R.; Vicini, P.; Boucaud, Ph.; 10.1016/S0920-5632(03)01755-9


    We present the current status of the apeNEXT project. Aim of this project is the development of the next generation of APE machines which will provide multi-teraflop computing power. Like previous machines, apeNEXT is based on a custom designed processor, which is specifically optimized for simulating QCD. We discuss the machine design, report on benchmarks, and give an overview on the status of the software development.

  12. Status of the apeNEXT project

    Energy Technology Data Exchange (ETDEWEB)

    Ammendola, R.; Bodin, F.; Boucaud, Ph.; Cabibbo, N.; Di Carlo, F.; De Pietri, R.; Di Renzo, F.; Errico, W.; Fucci, A.; Guagnelli, M.; Kaldass, H.; Lonardo, A.; Lucad, S. de; Micheli, J.; Morenas, V.; Pene, O.; Petronzio, R.; Palombi, F.; Pleiter, D.; Paschedag, N.; Rapuano, F.; De Riso, P.; Salamon, A.; Salina, G.; Sartori, L.; Schifano, F.; Simma, H.; Tripiccione, R.; Vicini, P


    We present the current status of the apeNEXT project. Aim of this project is the development of the next generation of APE machines which will provide multi-teraflop computing power. Like previous machines, apeNEXT is based on a custom designed processor, which is specifically optimized for simulating QCD. We discuss the machine design, report on benchmarks, and give an overview on the status of the software development.

  13. The advanced main control console for next japanese PWR plants

    Energy Technology Data Exchange (ETDEWEB)

    Tsuchiya, A. [Hokkaido Electric Power Co., Inc., Sapporo (Japan); Ito, K. [Mitsubishi Heavy Industries, Ltd., Nuclear Energy Systems Engineering Center, Yokohama (Japan); Yokoyama, M. [Mitsubishi Electric Corporation, Energy and Industrial Systems Center, Kobe (Japan)


    The purpose of the improvement of main control room designing in a nuclear power plant is to reduce operators' workload and potential human errors by offering a better working environment where operators can maximize their abilities. In order to satisfy such requirements, the design of main control board applied to Japanese Pressurized Water Reactor (PWR) type nuclear power plant has been continuously modified and improved. the Japanese Pressurized Water Reactor (PWR) Utilities (Electric Power Companies) and Mitsubishi Group have developed an advanced main control board (console) reflecting on the study of human factors, as well as using a state of the art electronics technology. In this report, we would like to introduce the configuration and features of the Advanced Main Control Console for the practical application to the next generation PWR type nuclear power plants including TOMARI No.3 Unit of Hokkaido Electric Power Co., Inc. (author)

  14. Core design analysis of the supercritical water fast reactor

    Energy Technology Data Exchange (ETDEWEB)

    Mori, M.


    Light Water Reactor technology is nowadays the most successful commercial application of fission reactors for the production of electricity. However, in the next years, nuclear industry will have to face new and demanding challenges. The need for sustainable and cheap sources of energy, the need for public acceptance, the need for even higher safety standards, the need to minimize waste production are only a few examples. It is for these very reasons that a few next generation nuclear reactor concepts were selected for extensive research and development. Super critical water cooled reactors are one of them. The use of a supercritical coolant would in fact allow for higher thermal efficiencies and a more compact plant design. As a matter of fact, steam generators, or steam separators and driers would not be needed thus, significantly reducing construction costs. Moreover, because of the high heat capacity of supercritical water, comparatively less coolant would be needed to refrigerate the reactor. Consequently, a water-cooled reactor with a fast neutron spectrum could potentially be designed: the SuperCritical water Fast Reactor. This system presents unique features combining well-known fast and light water reactor characteristics in one design (e.g. the tendency to a positive void reactivity coefficient together with Loss Of Coolant Accidents, as design basis). The core is in fact loaded with highly enriched Mixed Oxide fuel (average plutonium content of {approx}23%), and presents a peculiar and significant geometrical and material heterogeneity (use of radial and axial blankets, solid moderator layers, several enrichment zones). The safety analysis of this very complex core layout, the development of suitable tools of investigation, and the optimization of the void reactivity effect through core design, is the main objective of this work. (orig.)

  15. Modeling the Stepping Process of Negative Lightning Stepped Leaders

    Directory of Open Access Journals (Sweden)

    Vernon Cooray


    Full Text Available A physical model based on the mechanism observed in experimental investigations is introduced to describe the formation of negative leader steps. Starting with a small length of a space leader located at the periphery of the negative streamer system of the stepped leader, the model simulates the growth and the subsequent formation of the leader step. Based on the model, the step length, the step forming time, and the propagation speed of stepped leaders as a function of the prospective return stroke peak current are estimated. The results show that the step length and the leader speed increase with increasing prospective return stroke current. The results also show that the speed of the stepped leader increases as it approaches the ground. For prospective return stroke currents in the range of 15 kA–60 kA, the step lengths lie within the range 5 m–100 m, the step forming times lie within the range 10 μs–250 μs, and the leader speed lies within the range 105 m/s −1.5 × 106 m/s. The results obtained are in reasonable agreement with the experimental observations.

  16. 78 FR 71675 - Update of the Office of Nuclear Reactor Regulation's Electronic Operating Reactor Correspondence (United States)


    ... From the Federal Register Online via the Government Publishing Office NUCLEAR REGULATORY COMMISSION Update of the Office of Nuclear Reactor Regulation's Electronic Operating Reactor Correspondence... Regulatory Commission. Michele G. Evans, Director, Division of Operating Reactor Licensing, Office of Nuclear...

  17. ICARUS mission, next step of coronal exploration after Solar Orbiter and Solar Probe Plus (United States)

    Krasnoselskikh, Vladimir; Tsurutani, Bruce T.; Velli, Marco; Maksimovic, Milan; Balikhin, Mikhael; Dudok de Wit, Thierry; Kretzschmar, Matthieu


    The primary scientific goal of ICARUS (Investigation of Coronal AcceleRation and heating Up to the Sun), a mother-daughter satellite mission, will be to determine how the magnetic _field and plasma dynamics in the outer solar atmosphere give rise to the corona, the solar wind and the entire heliosphere. Reaching this goal will be a Rosetta-stone step, with results broadly applicable within the fields of space plasma physics and astrophysics. Within ESA's Cosmic Vision roadmap, these science goals address Theme 2: How does the solar system work ?" by investigating basic processes occurring From the Sun to the edge of the Solar System". ICARUS will not only advance our understanding of the plasma environment around our the Sun, but also of the numerous magnetically active stars with hot plasma coronae. ICARUS I will perform the first-ever direct in situ measurements of electromagnetic fields, particle acceleration, wave activity, energy distribution and flows directly in the regions where the solar wind emerges from the coronal plasma. ICARUS I will have a perihelion at 1 Solar radius from its surface, it will cross the region where the major energy deposition occurs. The polar orbit of ICARUS I will enable crossing the regions where both the fast and slow wind are generated. It will probe local characteristics of the plasma and provide unique information about the physical processes involved in the creation of the solar wind. ICARUS II will observe this region using remote-sensing instruments, providing simultaneous information about regions crossed by ICARUS I and the solar atmosphere below as observed by solar telescopes. It will thus provide bridges for understanding the magnetic links between the heliosphere and the solar atmosphere. Such information is crucial to our understanding of the plasma physics and electrodynamics of the solar atmosphere. ICARUS II will also play a very important relay role, enabling the radio-link with ICARUS I. It will receive

  18. Thermonuclear Burning as a Probe of Neutron Star (United States)

    Strohmayer, Tod


    Thermonuclear fusion is a fundamental process taking place in the matter transferred onto neutron stars in accreting binary systems. The heat deposited by nuclear reactions becomes readily visible in the X-ray band when the burning is either unstable or marginally stable, and results in the rich phenomenology of X-ray bursts, superbursts, and mHz quasiperiodic oscillations. Fast X-ray timing observations with NASA's Rossi X-ray Timing Explorer (RXTE) over the past decade have revealed a wealth of new phenomena associated with thermonuclear burning on neutron stars, including the discovery of nuclear powered pulsations during X-ray bursts and superbursts. I will briefly review our current observational and theoretical understanding of these new phenomena, with an emphasis on recent findings, and discuss what they are telling us about the structure of neutron stars.

  19. The Westinghouse Small Modular Reactor Design

    Energy Technology Data Exchange (ETDEWEB)

    Gutierrez Garcia, F. J.; Memmott, M. J.


    Westinghouse has developed a small modular reactor (SMR) which incorporates an integral pressurized water reactor (PWR) design. The Westinghouse SMR design also utilizes many of the key features and innovative concepts from the AP1000 plant, including passive safety systems.

  20. Conceptual design of the Fast-Liner Reactor (FLR) for fusion power

    Energy Technology Data Exchange (ETDEWEB)

    Moses, R.W.; Krakowski, R.A.; Miller, R.L.


    The generation of fusion power from the Fast-Liner Reactor (FLR) concept envisages the implosion of a thin (3-mm) metallic cylinder (0.2-m radius by 0.2-m length) onto a preinjected plasma. This plasma would be heated to thermonuclear temperatures by adiabatic compression, pressure confinement would be provided by the liner inertia, and thermal insulation of the wall-confined plasma would be established by an embedded azimuthal magnetic field. A 2- to 3-mu s burn would follow the approx. 10/sup 4/ m/s radial implosion and would result in a thermonuclear yield equal to 10 to 15 times the energy initially invested into the liner kinetic energy. For implosions occurring once every 10 s a gross thermal power of 430 MWt would be generated. The results of a comprehensive systems study of both physics and technology (economics) optima are presented. Despite unresolved problems associated with both the physics and technology of the FLR, a conceptual power plant design is presented.

  1. Performance of BNFL SBR MOX fuel for the next decade

    Energy Technology Data Exchange (ETDEWEB)

    Brown, C.; Cook, P.; Edwards, J.; Fisher, S. [BNFL, Sellafield, Seascale Cumbria (United Kingdom); Gates, G. [BNFL, secondee to OECD Halden Reactor Project (United Kingdom); Palmer, I. [BNFL, Springfields (United Kingdom); White, R. [BNFL (United Kingdom)


    BNFL is actively involved in the irradiation testing and development of its SBR MOX fuel in support of the Sellafield MOX Plant (SMP) and fuel production in the next century. The BNFL MOX fuel development programme is comprehensive and covers a wide range of irradiation conditions. In particular, results are presented in the following areas: as-fabricated pellet characterization; fuel irradiations in Halden and other reactors; PIE on commercially irradiated fuel; fuel modelling. BNFL will continue its testing and development programme on SBR MOX fuel into the next decade and beyond in support of its customers. Extensive PIE and irradiation testing are planned on the first fuel to be manufactured in SMP to confirm the good performance of SBR MOX fuel. (authors)

  2. Local Thermonuclear Runaways in Dwarf Novae? (United States)

    Shara, Michael


    We have no hope of understanding the structure and evolution of a class of astrophysical objects if we cannot identify the dominant energy source of those objects.The Disk Instability Model {DIM} postulates that Dwarf Nova {DN} outbursts are powered by runaway accretion from an accretion disk onto a White Dwarf {WD} in a red dwarf-WD mass transferring binary. Ominously, HST observations {e.g. Sion et al. 2001} of WD surface abundances hint at a significant shortcoming of the DIM. The data from the present proposal will be able to unequivocally demonstrate if the observed highly Carbon-depleted and Nitrogen-enhanced abundances on WD surfaces {NOT predicted by DIM} vary with binary orbital phase, or throughout a DN quiescence cycle, or from cycle to cycle. These same data will test if predicted {but never observed} Local Thermonuclear Runaways {"Nuclear-powered mini-novas"} occur on the WDs of DN. Such events could trigger or even power DN, providing the long-sought physical mechanism of DN eruptions that DIM lacks. As a "free" bonus, the same data may also directly detect the diffusion of accreted metals in a WD atmosphere for the first time, or provide significant limits on the diffusion rate.

  3. First steps towards a Zn/Co(III)sep-driven P450 BM3 reactor. (United States)

    Zhao, Liqing; Güven, Güray; Li, Yin; Schwaneberg, Ulrich


    Cytochrome P450s are synthetically attractive hydroxylation catalysts. For cell-free applications, a constant supply of NAD(P)H can be very costly. Mediators such as Zn/Co(III)sep can be an alternative cofactor system to NAD(P)H. Several mutants of cytochrome P450 BM3 with improved electron transfer rate to Zn/Co(III)sep have been obtained in our group. P450 BM3 M7 (F87A V281G M354S R471C A1011T S1016G Q1022R) was immobilized on DEAE-650S, further entrapped with k-carrageenan together with zinc dust which function as electron source and catalase which removes produced hydrogen peroxide instantly. Immobilized P450 BM3 M7 were treated with 0.05% (v/v) glutaraldehyde to enhance operational stability. P450 BM3 M7 retained around 76% of its activity and conversions stayed above 80% in 10 batch cycles, indicating a high stability of immobilized P450 BM3 M7. To explore the synthetic potential, a small-scale bioreactor was developed to investigate the stability and efficiencies of P450 BM3 M9 (R47F F87A M238K V281G M354S D363H W575C A595T). P450 BM3 M9 was used for the continuous conversion of 3-phenoxytoluene in a plug flow reactor (PFR) since P450 BM3 M9 has a 3-fold higher activity for 3-phenoxytoluene compared to P450 BM3 M7 which was used for optimizing immobilization conditions with the highest activity for 12-pNCA assay. The reactor could be operated for 5 days with total turnover numbers (TTNs) over 2,000.

  4. Analysis of Fluid Flow and Heat Transfer Model for the Pebble Bed High Temperature Gas Cooled Reactor


    S. Yamoah; E.H.K. Akaho; Nana G.A. Ayensu; M. Asamoah


    The pebble bed type high temperature gas cooled nuclear reactor is a promising option for next generation reactor technology and has the potential to provide high efficiency and cost effective electricity generation. The reactor unit heat transfer poses a challenge due to the complexity associated with the thermalflow design. Therefore to reliably simulate the flow and heat transport of the pebble bed modular reactor necessitates a heat transfer model that deals with radiation as well as ther...

  5. MIXMETER - the final steps

    Energy Technology Data Exchange (ETDEWEB)

    Harrison, P.S. [Melverley Consultants Ltd (United Kingdom); Parry, S.J. [Imperial College, London (United Kingdom). Dept. of Chemical Engineering and Chemical Technology; Shires, G.L. [Imperial College, London (United Kingdom). TH Huxley School of Environment


    The MIXMETER multiphase flow meter has been in development since 1992 by Imperial College, London, through a project sponsored by the UK Offshore Supplies Office (OSO) and a consortium of oil companies. During the final stage of this development in 1997 a 3 inch (75mm) Production Prototype meter was built by the licensees, Jiskoot Autocontrol Ltd, and has since been tested under The National Engineering Laboratory (NEL) 'Multiflow' programme. Tests in the vertical orientation (upward flow) have also been performed together with heavy oil tests at the Texaco Flow Facility in Humble, Texas. Key aspects of these tests are discussed. An important element of the NEL tests was to assess the performance of the meter when salt concentration of the water phase varies. These results are discussed together with a novel technique for enhancement of the dual energy gamma system to allow salt concentration to be measured and the necessary corrections to be performed without the need for additional equipment. (author)

  6. Department of Thermonuclear Research annual report 1992

    Energy Technology Data Exchange (ETDEWEB)

    Sadowski, M.; Pawlowicz, W. [eds.] [Soltan Inst. for Nuclear Studies, Otwock-Swierk (Poland)


    Department of Thermonuclear Research annual report 1992 presents the most important results of theoretical, experimental and technological studies carried out within a framework of the research program - Plasma Physics and an additional grant - Study of Surface Melting of Selected Materials with a Plasma stream (contract with the Committee for Scientific Research - KBN). Theoretical studies of tokamak edge plasmas, atomic collisions, heat transfer, and numerical codes, are shortly summarized. Experimental studies of X-rays and particles emitted from Plasma-Focus facilities, calibration of nuclear track detectors, optimization of PF discharges with additional gas targets, magnetic probe measurements, new diagnostic and experimental arrangements, as well as mass- and energy-analysis of ions from IONOTRON-type devices, are described. Also presented are technological studies, modernization of experimental facilities, design of new control systems, tests on uniformity and reproducibility of plasma streams as the formation of photovoltaic cells and modifications of solid surfaces by means of plasma streams from the IONOTRON and PF devices. (author).

  7. Nuclear heating experiments for the validation of fusion reactor shielding performance

    Energy Technology Data Exchange (ETDEWEB)

    Batistoni, P. [Associazione EURATOM-ENEA sulla Fusione, Frascati (Italy); Angelone, M. [Associazione EURATOM-ENEA sulla Fusione, Frascati (Italy); Pillon, M. [Associazione EURATOM-ENEA sulla Fusione, Frascati (Italy); Rado, V. [Associazione EURATOM-ENEA sulla Fusione, Frascati (Italy)


    Nuclear heating experiments were performed at the 14 MeV Frascati neutron generator, with the purpose of validating the shielding performance of the International Thermonuclear Experiment Reactor (ITER) shielding system (first wall, shielding blanket and vacuum vessel). The experiments consisted of the irradiation, with 14 MeV neutrons, of large assemblies that simulated, for size and material composition, the shielding system and the toroidal field magnet. The nuclear heating was measured with different thermo-luminescent detectors, as a function of the penetration depth inside the assemblies. The experimental results obtained were compared with the same quantities calculated with the same nuclear database and code used for nuclear heating calculations in the ITER design. (orig.)

  8. General meeting. Technical reunion: the numerical and experimental simulation applied to the Reactor Physics; Assemblee generale. Reunion technique: la simulation numerique et experimentale appliquee a la physique des reacteurs

    Energy Technology Data Exchange (ETDEWEB)



    The SFEN (French Society on Nuclear Energy), organized the 18 october 2001 at Paris, a technical day on the numerical and experimental simulation, applied to the reactor Physics. Nine aspects were discussed, giving a state of the art in the domain:the french nuclear park; the future technology; the controlled thermonuclear fusion; the new organizations and their implications on the research and development programs; Framatome-ANP markets and industrial code packages; reactor core simulation at high temperature; software architecture; SALOME; DESCARTES. (A.L.B.)

  9. Bringing mask repair to the next level (United States)

    Edinger, K.; Wolff, K.; Steigerwald, H.; Auth, N.; Spies, P.; Oster, J.; Schneider, H.; Budach, M.; Hofmann, T.; Waiblinger, M.


    Mask repair is an essential step in the mask manufacturing process as the extension of 193nm technology and the insertion of EUV are drivers for mask complexity and cost. The ability to repair all types of defects on all mask blank materials is crucial for the economic success of a mask shop operation. In the future mask repair is facing several challenges. The mask minimum features sizes are shrinking and require a higher resolution repair tool. At the same time mask blanks with different new mask materials are introduced to optimize optical performance and long term durability. For EUV masks new classes of defects like multilayer and phase defects are entering the stage. In order to achieve a high yield, mask repair has to cover etch and deposition capabilities and must not damage the mask. These challenges require sophisticated technologies to bring mask repair to the next level. For high end masks ion-beam based and e-based repair technologies are the obvious choice when it comes to the repair of small features. Both technologies have their pro and cons. The scope of this paper is to review and compare the performance of ion-beam based mask repair to e-beam based mask repair. We will analyze the limits of both technologies theoretically and experimentally and show mask repair related performance data. Based on this data, we will give an outlook to future mask repair tools.

  10. The model of turbulent mixing zone evolution, which accounts for the deviation from spherical symmetry of laser thermonuclear target compression (United States)

    Yakhin, R.; Rozanov, V.; Doskoch, I.; Zmitrenko, N.; Proncheva, N.


    The present report presents an analytical model destined to describe the development of hydrodynamic instabilities and their influence on the neutron yield under laser target compression. A number of specific numerical simulations formed the basis of the analysis. The plane and spherical tasks with certain initial conditions were considered. In a plane case the two pairs of gases typical for the shock tube experiments were studied. The spherical task was the modeling one and involved a small number of harmonics (the calculation parameters corresponded to the regime of laser compression). A notable difference in the calculation parameters of the gases in shock tubes and the laser compressed targets is not an obstacle for the construction of a unified model, since in gas dynamic problems the fundamental properties of gas-dynamic similarity are fulfilled. Basing on the simulations [1] and theory [2], the authors constructed a model of mixing zone development, which takes into account the initial conditions of perturbation. In addition to the earlier studied problems the report presents 2D-simulations of spherical target compression with account for the mixing processes. The simulations were aimed at determination of the degree of the mixing zone influence on the neutron yield.

  11. On the Convexity of Step out - Step in Sequencing Games

    NARCIS (Netherlands)

    Musegaas, Marieke; Borm, Peter; Quant, Marieke


    The main result of this paper is the convexity of Step out - Step in (SoSi) sequencing games, a class of relaxed sequencing games first analyzed by Musegaas, Borm, and Quant (2015). The proof makes use of a polynomial time algorithm determining the value and an optimal processing order for an

  12. 8th International School of Fusion Reactor Technology "Ettore Majorana"

    CERN Document Server

    Leotta, G G; Muon-catalyzed fusion and fusion with polarized nuclei


    The International School of Fusion Reactor Technology started its courses 15 years ago and since then has mantained a biennial pace. Generally, each course has developed the subject which was announced in advance at the closing of the previous course. The subject to which the present proceedings refer was chosen in violation of that rule so as to satisfy the recent and diffuse interest in cold fusion among the main European laboratories involved in controlled thermonuclear research (CTR). In the second half of 1986 we started to prepare a workshop aimed at assessing the state of the art and possibly of the perspectives of muon- catalyzed fusion. Research in this field has recently produced exciting experimental results open to important practical applications. We thought it worthwhile to consider also the beneficial effects and problems of the polarization ofthe nuclei in both cold and thermonuclear fusion. In preparing the 8th Course on Fusion Reactor Technology, it was necessary to abandon the tradi...

  13. Life of War, Death of the Rest: The Shining Path of Cormac McCarthy's Thermonuclear America (United States)

    Blackmore, Tim


    The Bush Administration's quiet resumption of, or initiation of new, nuclear weapons programs aimed militarizing space, and erecting a missile defense shield that would have the effect of rolling back 19 years of solid detente, has gone largely unnoticed over the last eight years. Weapons makers, government officials and politicians have expressed…

  14. The Status of the US High-Temperature Gas Reactors

    Directory of Open Access Journals (Sweden)

    Andrew C. Kadak


    Full Text Available In 2005, the US passed the Energy Policy Act of 2005 mandating the construction and operation of a high-temperature gas reactor (HTGR by 2021. This law was passed after a multiyear study by national experts on what future nuclear technologies should be developed. As a result of the Act, the US Congress chose to develop the so-called Next-Generation Nuclear Plant, which was to be an HTGR designed to produce process heat for hydrogen production. Despite high hopes and expectations, the current status is that high temperature reactors have been relegated to completing research programs on advanced fuels, graphite and materials with no plans to build a demonstration plant as required by the US Congress in 2005. There are many reasons behind this diminution of HTGR development, including but not limited to insufficient government funding requirements for research, unrealistically high temperature requirements for the reactor, the delay in the need for a “hydrogen” economy, competition from light water small modular light water reactors, little utility interest in new technologies, very low natural gas prices in the US, and a challenging licensing process in the US for non-water reactors.

  15. Cuba: The Next Unanticipated Anticipated Strategic Crisis?

    National Research Council Canada - National Science Library

    Gorrell, Tim


    ...; and the current Bush administration with the global war on terrorism (GWOT). Cuba, specifically post-Castro Cuba, could very well trigger the next unanticipated crisis even though the writing is on the...


    Directory of Open Access Journals (Sweden)

    Constantin POPESCU


    Full Text Available The authors contribution to this paper is to present a concept solution of a remote control robot (RCR used for the horizontal fuel channels pressure tube decommissioning in the CANDU nuclear reactor. The authors highlight in this paper, few details of geometry, operations, constraints by kinematics and dynamics of the robot movement outside of the reactor fuel channel. Outside operations performed has as the main steps of dismantling process the followings: positioning front of Calandria structure at the fuel channel to be decommissioned, coupling and locking to the End Fitting (EF, sorting and storage extracted items in the safe container. All steps are performed in automatic mode. The remote control robot (RCR represents a safety system controlled by sensors and has the capability to analyze any error registered and decide next activities or abort the outside decommissioning procedure in case of any risk rise in order to ensure the environmental and workers protection.

  17. Flux decay during thermonuclear X-ray bursts analysed with the dynamic power-law index method (United States)

    Kuuttila, J.; Kajava, J. J. E.; Nättilä, J.; Motta, S. E.; Sánchez-Fernández, C.; Kuulkers, E.; Cumming, A.; Poutanen, J.


    The cooling of type-I X-ray bursts can be used to probe the nuclear burning conditions in neutron star envelopes. The flux decay of the bursts has been traditionally modelled with an exponential, even if theoretical considerations predict power-law-like decays. We have analysed a total of 540 type-I X-ray bursts from five low-mass X-ray binaries observed with the Rossi X-ray Timing Explorer. We grouped the bursts according to the source spectral state during which they were observed (hard or soft), flagging those bursts that showed signs of photospheric radius expansion (PRE). The decay phase of all the bursts were then fitted with a dynamic power-law index method. This method provides a new way of probing the chemical composition of the accreted material. Our results show that in the hydrogen-rich sources the power-law decay index is variable during the burst tails and that simple cooling models qualitatively describe the cooling of presumably helium-rich sources 4U 1728-34 and 3A 1820-303. The cooling in the hydrogen-rich sources 4U 1608-52, 4U 1636-536, and GS 1826-24, instead, is clearly different and depends on the spectral states and whether PRE occurred or not. Especially the hard state bursts behave differently than the models predict, exhibiting a peculiar rise in the cooling index at low burst fluxes, which suggests that the cooling in the tail is much faster than expected. Our results indicate that the drivers of the bursting behaviour are not only the accretion rate and chemical composition of the accreted material, but also the cooling that is somehow linked to the spectral states. The latter suggests that the properties of the burning layers deep in the neutron star envelope might be impacted differently depending on the spectral state.

  18. Puzzling thermonuclear burst behaviour from the transient low-mass X-ray binary IGR J17473-2721

    DEFF Research Database (Denmark)

    Chenevez, Jérôme


    . The wide range of inferred accretion rates (between 20% of the Eddington accretion rate m˙ Edd) spanned during the outburst allows us to study changes in the nuclear burning processes and to identify up to seven different phases. The burst rate increased gradually with the accretion rate until...

  19. The Next Generation of ABA Providers. (United States)

    Dixon, Mark R


    The imbalance of supply and demand for behavior analytic services will change in the near future. Behavior analysts, who want to survive in an increasing competitive marketplace, will need to show quality results and better results than the next behavior analyst. Trumpet Behavioral Health is a company designed to infuse scientific research with clinical practices. In the years ahead, look to companies like Trumpet as role models of the next generation of autism service providers.

  20. Symmetrically converging plane thermonuclear burn waves (United States)

    Charakhch'yan, A. A.; Khishchenko, K. V.


    Five variants of a one-dimensional problem on synchronous bilateral action of two identical drivers on opposite surfaces of a plane layer of DT fuel with the normal or five times greater initial density, where the solution includes two thermonuclear burn waves propagating to meet one another at the symmetry plane, are simulated. A laser pulse with total absorption of energy at the critical density (in two variants) and a proton bunch that provides for a nearly isochoric heating (in three variants) are considered as drivers. A wide-range equation of state for the fuel, electron and ion heat conduction, self-radiation of plasma and plasma heating by α-particles are taken into account. In spite of different ways of ignition, various models of α-particle heat, whether the burn wave remains slow or transforms into the detonation wave, and regardless of way of such a transformation, the final value of the burn-up factor depends essentially on the only parameter Hρ0, where H is the half-thickness of the layer and ρ0 is the initial fuel density. This factor is about 0.35 at Hρ0 ≈ 1 g cm-2 and about 0.7 at Hρ0 ≈ 5 g cm-2. The expansion stage of the flow (after reflecting the burn or detonation wave from the symmetry plane) gives the main contribution in forming the final values of the burn-up factor and the gain at Hρ0 ≈ 1 g cm-2 and increases them approximately two times at Hρ0 ≈ 5 g cm-2. In the case of the proton driver, the final value of the gain is about 200 at Hρ0 ≈ 1 g cm-2 and about 2000 at Hρ0 ≈ 5 g cm-2. In the case of the laser driver, the above values are four times less in conformity with the difference between the driver energies.

  1. Current Reactor Physics Benchmark Activities at the Idaho National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    John D. Bess; Margaret A. Marshall; Mackenzie L. Gorham; Joseph Christensen; James C. Turnbull; Kim Clark


    The International Reactor Physics Experiment Evaluation Project (IRPhEP) [1] and the International Criticality Safety Benchmark Evaluation Project (ICSBEP) [2] were established to preserve integral reactor physics and criticality experiment data for present and future research. These valuable assets provide the basis for recording, developing, and validating our integral nuclear data, and experimental and computational methods. These projects are managed through the Idaho National Laboratory (INL) and the Organisation for Economic Co-operation and Development Nuclear Energy Agency (OECD-NEA). Staff and students at the Department of Energy - Idaho (DOE-ID) and INL are engaged in the development of benchmarks to support ongoing research activities. These benchmarks include reactors or assemblies that support Next Generation Nuclear Plant (NGNP) research, space nuclear Fission Surface Power System (FSPS) design validation, and currently operational facilities in Southeastern Idaho.

  2. "A New Class od Functionally Graded Cearamic-Metal Composites for Next Generation Very High Temperature Reactors"

    Energy Technology Data Exchange (ETDEWEB)

    Dr. Mohit Jain; Dr. Ganesh Skandan; Dr. Gordon E. Khose; Mrs. Judith Maro, Nuclear Reactor Laboratory, MIT


    Generation IV Very High Temperature power generating nuclear reactors will operate at temperatures greater than 900 oC. At these temperatures, the components operating in these reactors need to be fabricated from materials with excellent thermo-mechanical properties. Conventional pure or composite materials have fallen short in delivering the desired performance. New materials, or conventional materials with new microstructures, and associated processing technologies are needed to meet these materials challenges. Using the concept of functionally graded materials, we have fabricated a composite material which has taken advantages of the mechanical and thermal properties of ceramic and metals. Functionally-graded composite samples with various microstructures were fabricated. It was demonstrated that the composition and spatial variation in the composition of the composite can be controlled. Some of the samples were tested for irradiation resistance to neutrons. The samples did not degrade during initial neutron irradiation testing.

  3. Defining excellence: next steps for practicing clinicians seeking to prevent diagnostic error


    Foster, Paul N.; Klein, Julie R.


    The Institute of Medicine (IOM) released its report on diagnostic errors in September, 2015. The report highlights the urgency of reducing errors and calls for system-level intervention and changes in our basic clinical interactions. Using the report?s controversial definition of diagnostic error as a starting point, we introduce the issues and the potential impact on practicing physicians. We report a case used to illustrate this in an academic conference. Finally, we turn to the challenge o...

  4. Technical Readiness of CTBT Monitoring Regime and Next Steps for Entry into Force (United States)

    Zerbo, L.


    2016 marks the 20th anniversary of the opening for signature of the Comprehensive Nuclear-Test-Ban Treaty (CTBT). The strength of the CTBT lies in the fact that it is supported by a solid and proven verification regime. Made up of 337 monitoring facilities (using seismic, hydroacoustic, infrasound and radionuclide technologies) as well as 250 communication facilities, the International Monitoring System has global reach and is approximately 90% complete. Significant opportunities to the further build-up of the IMS network are being realized and technological advancements are being pursued in earnest. This represents an unprecedented achievement in the history of multilateral verification. The timely detection of the 4 announced nuclear tests by the Democratic People's Republic of Korea is proof of the effectiveness and utility of our data. Following the most recent DPRK nuclear test in January of this year, States were provided with automated and reviewed data on the event well within the short timelines provided for by the Treaty. Despite the advances in monitoring and detection capability, the CTBT has not yet become international law. The Treaty has 183 States Signatories and 164 ratifying States, but will not enter into force until the remaining 8 so-called "Annex 2" States complete their ratification procedures. This presentation will reflect on the de facto benefits that the Treaty has already brought, but also on the challenges that remain, both in terms of ensuring that the verification regime keeps pace with developments in science and technology and in securing a de jure global ban on nuclear testing.

  5. Alkaline RFC Space Station prototype - 'Next step Space Station'. [Regenerative Fuel Cells (United States)

    Hackler, I. M.


    The regenerative fuel cell, a candidate technology for the Space Station's energy storage system, is described. An advanced development program was initiated to design, manufacture, and integrate a regenerative fuel cell Space Station prototype (RFC SSP). The RFC SSP incorporates long-life fuel cell technology, increased cell area for the fuel cells, and high voltage cell stacks for both units. The RFC SSP's potential for integration with the Space Station's life support and propulsion systems is discussed.

  6. 75 FR 54403 - U.S. National Climate Assessment Objectives, Proposed Topics, and Next Steps (United States)


    ... Climate Assessment (NCA), a project of the U.S. Global Change Research Program, by engaging people who are.... Analyzes the effects of global change on the natural environment, agriculture, energy production and use... change. The approach that is envisioned for this NCA is a comprehensive assessment of climate change...

  7. United States Health Care Reform: Progress to Date and Next Steps. (United States)

    Obama, Barack


    The Affordable Care Act is the most important health care legislation enacted in the United States since the creation of Medicare and Medicaid in 1965. The law implemented comprehensive reforms designed to improve the accessibility, affordability, and quality of health care. To review the factors influencing the decision to pursue health reform, summarize evidence on the effects of the law to date, recommend actions that could improve the health care system, and identify general lessons for public policy from the Affordable Care Act. Analysis of publicly available data, data obtained from government agencies, and published research findings. The period examined extends from 1963 to early 2016. The Affordable Care Act has made significant progress toward solving long-standing challenges facing the US health care system related to access, affordability, and quality of care. Since the Affordable Care Act became law, the uninsured rate has declined by 43%, from 16.0% in 2010 to 9.1% in 2015, primarily because of the law's reforms. Research has documented accompanying improvements in access to care (for example, an estimated reduction in the share of nonelderly adults unable to afford care of 5.5 percentage points), financial security (for example, an estimated reduction in debts sent to collection of $600-$1000 per person gaining Medicaid coverage), and health (for example, an estimated reduction in the share of nonelderly adults reporting fair or poor health of 3.4 percentage points). The law has also begun the process of transforming health care payment systems, with an estimated 30% of traditional Medicare payments now flowing through alternative payment models like bundled payments or accountable care organizations. These and related reforms have contributed to a sustained period of slow growth in per-enrollee health care spending and improvements in health care quality. Despite this progress, major opportunities to improve the health care system remain. Policy

  8. Perspectives on Next Steps in Classification of Orofacial Pain – Part 2: Role of psychosocial factors (United States)

    Durham, Justin; Raphael, Karen G.; Benoliel, Rafael; Ceusters, Werner; Michelotti, Ambra; Ohrbach, Richard


    This paper was initiated by a symposium, in which the present authors contributed, organised by the International RDC/TMD Consortium Network in March 2013. The purpose of the paper is to review the status of biobehavioural research – both quantitative and qualitative – related to orofacial pain with respect to the etiology, pathophysiology, diagnosis and management of orofacial pain conditions, and how this information can optimally be used for developing a structured orofacial pain classification system for research. In particular, we address: representation of psychosocial entities in classification systems, use of qualitative research to identify and understand the full scope of psychosocial entities and their interaction, and the usage of classification system for guiding treatment. We then provide recommendations for addressing these problems, including how ontological principles can inform this process. PMID:26257252

  9. Knowledge Based Artificial Augmentation Intelligence Technology: Next Step in Academic Instructional Tools for Distance Learning (United States)

    Crowe, Dale; LaPierre, Martin; Kebritchi, Mansureh


    With augmented intelligence/knowledge based system (KBS) it is now possible to develop distance learning applications to support both curriculum and administrative tasks. Instructional designers and information technology (IT) professionals are now moving from the programmable systems era that started in the 1950s to the cognitive computing era.…

  10. Perinatal Risks and Childhood Premorbid Indicators of Later Psychosis: Next Steps for Early Psychosocial Interventions. (United States)

    Liu, Cindy H; Keshavan, Matcheri S; Tronick, Ed; Seidman, Larry J


    Schizophrenia and affective psychoses are debilitating disorders that together affect 2%-3% of the adult population. Approximately 50%-70% of the offspring of parents with schizophrenia manifest a range of observable difficulties including socioemotional, cognitive, neuromotor, speech-language problems, and psychopathology, and roughly 10% will develop psychosis. Despite the voluminous work on premorbid vulnerabilities to psychosis, especially on schizophrenia, the work on premorbid intervention approaches is scarce. While later interventions during the clinical high-risk (CHR) phase of psychosis, characterized primarily by attenuated positive symptoms, are promising, the CHR period is a relatively late phase of developmental derailment. This article reviews and proposes potential targets for psychosocial interventions during the premorbid period, complementing biological interventions described by others in this Special Theme issue. Beginning with pregnancy, parents with psychoses may benefit from enhanced prenatal care, social support, parenting skills, reduction of symptoms, and programs that are family-centered. For children at risk, we propose preemptive early intervention and cognitive remediation. Empirical research is needed to evaluate these interventions for parents and determine whether interventions for parents and children positively influence the developmental course of the offspring. © The Author 2015. Published by Oxford University Press on behalf of the Maryland Psychiatric Research Center. All rights reserved. For permissions, please email:

  11. Creating a Pilot Educational Psychiatry Website: Opportunities, Barriers, and Next Steps. (United States)

    Torous, John; O'Connor, Ryan; Franzen, Jamie; Snow, Caitlin; Boland, Robert; Kitts, Robert


    While medical students and residents may be utilizing websites as online learning resources, medical trainees and educators now have the opportunity to create such educational websites and digital tools on their own. However, the process and theory of building educational websites for medical education have not yet been fully explored. To understand the opportunities, barriers, and process of creating a novel medical educational website. We created a pilot psychiatric educational website to better understand the options, opportunities, challenges, and processes involved in the creation of a psychiatric educational website. We sought to integrate visual and interactive Web design elements to underscore the potential of such Web technology. A pilot website (PsychOnCall) was created to demonstrate the potential of Web technology in medical and psychiatric education. Creating an educational website is now technically easier than ever before, and the primary challenge no longer is technology but rather the creation, validation, and maintenance of information for such websites as well as translating text-based didactics into visual and interactive tools. Medical educators can influence the design and implementation of online educational resources through creating their own websites and engaging medical students and residents in the process.

  12. Perspectives on next steps in classification of oro-facial pain - part 1: role of ontology. (United States)

    Ceusters, W; Michelotti, A; Raphael, K G; Durham, J; Ohrbach, R


    The purpose of this study was to review existing principles of oro-facial pain classifications and to specify design recommendations for a new system that would reflect recent insights in biomedical classification systems, terminologies and ontologies. The study was initiated by a symposium organised by the International RDC/TMD Consortium Network in March 2013, to which the present authors contributed. The following areas are addressed: problems with current classification approaches, status of the ontological basis of pain disorders, insufficient diagnostic aids and biomarkers for pain disorders, exploratory nature of current pain terminology and classification systems, and problems with prevailing classification methods from an ontological perspective. Four recommendations for addressing these problems are as follows: (i) develop a hypothesis-driven classification structure built on principles that ensure to our best understanding an accurate description of the relations among all entities involved in oro-facial pain disorders; (ii) take into account the physiology and phenomenology of oro-facial pain disorders to adequately represent both domains including psychosocial entities in a classification system; (iii) plan at the beginning for field-testing at strategic development stages; and (iv) consider how the classification system will be implemented. Implications in relation to the specific domains of psychosocial factors and biomarkers for inclusion into an oro-facial pain classification system are described in two separate papers. © 2015 John Wiley & Sons Ltd.

  13. Achieving Equity in Physical Activity Participation: ACSM Experience and Next Steps. (United States)

    Hasson, Rebecca E; Brown, David R; Dorn, Joan; Barkley, Lisa; Torgan, Carol; Whitt-Glover, Melicia; Ainsworth, Barbara; Keith, Nicole


    There is clear and consistent evidence that regular physical activity is an important component of healthy lifestyles and fundamental to promoting health and preventing disease. Despite the known benefits of physical activity participation, many people in the United States remain inactive. More specifically, physical activity behavior is socially patterned with lower participation rates among women; racial/ethnic minorities; sexual minority youth; individuals with less education; persons with physical, mental, and cognitive disabilities; individuals >65 yr of age; and those living in the southeast region of the United States. Many health-related outcomes follow a pattern that is similar to physical activity participation. In response to the problem of inequities in physical activity and overall health in the United States, the American College of Sports Medicine (ACSM) has developed a national roadmap that supports achieving health equity through a physically active lifestyle. The actionable, integrated pathways that provide the foundation of ACSM's roadmap include the following: 1) communication-raising awareness of the issue and magnitude of health inequities and conveying the power of physical activity in promoting health equity; 2) education-developing educational resources to improve cultural competency for health care providers and fitness professionals as well as developing new community-based programs for lay health workers; 3) collaboration-building partnerships and programs that integrate existing infrastructures and leverage institutional knowledge, reach, and voices of public, private, and community organizations; and 4) evaluation-ensuring that ACSM attains measurable progress in reducing physical activity disparities to promote health equity. This article provides a conceptual overview of these four pathways of ACSM's roadmap, an understanding of the challenges and advantages of implementing these components, and the organizational and economic

  14. Operation of the FRG-research reactors at Geesthacht

    Energy Technology Data Exchange (ETDEWEB)

    Reymann, A.; Krull, W. [GKSS-Forschungszentrum Geesthacht GmbH, Geesthacht-Tesperhude (Germany)


    Two research reactors have been operated very successfully by the GKSS research centre over decades in a connected pool system. FRG-1: 5 MW, criticality October 1958, FRG-2: 15 MW, criticality March 1963 and decommissioned February 1995. The FRG-2 was scheduled to stop operation in 1991 for lack of scientific and technical interest for future use. The reactor has been used as Germany's largest material testing reactor for power reactor fuel and power reactor materials development and safety tests. The FRG-2 has also played an important role in the conversion activities at the GKSS research centre. The FRG-1 is being used with high availability for beam tube experiments for fundamental and applied research in biology, membrane development, materials research, neutron radiography, neutron activation analyses etc. To enable the sufficient and efficient use of long wave length neutrons a cold neutron source has been installed in one of the beam tubes. The GKSS research centre, the advisory board, the scientific community and other clients are demanding the ongoing operation of the FRG-1 for at least till the year 2010. GKSS has taken many actions to ensure the save operation with high utilization and availability for the next 15 years. (author)

  15. Building an Interdisciplinary Research Program in Water Conservation: Approach, preliminary findings, and next steps


    Rosenberg, David E.; Endter-Wada, Joanna; Caplan, Arthur; Glenn, Diana T.; Ballard, Guy; Henderson, Katie


    Effective urban water conservation programs must harness a synergy of new technologies, public policies, social cost pricing, information dissemination, citizen engagement, and coordinated actions across decision making scales. Together, these factors affect the volume of water an individual user ultimately saves and the overall success of a conservation program or programs. Over the past 18 months, we have started building an interdisciplinary research program in urban water conservation to ...

  16. A Glance over Youth Footballers (Soccer Injury Profile: Next Step Required to Be Professional

    Directory of Open Access Journals (Sweden)

    Khatija Bahdur


    Full Text Available Youth football players are a special population of players. These developmental years play a key role in talent development and can build a good foundation for future success. Correct and age-appropriate training methods are essential for youth players, not just for development with regard to performance but also with regard to preventing injuries. Injuries sustained during the teenage years can create chronic problems for the player. This population is special because it is during these years that players undergo physical maturation, undergoing the changes within the body that is essential for the transition for child to adult. The rate and manner of physical maturation varies in each individual and planning around these changes is essential. Training loads, rest, and training types must be individualised to maximise progression as a player and prevent injury. The lower limbs are most susceptible to injury with the thighs, knee, ankles, groin and calf identified as common injury sites. In order to prevent injury, it is important to implement correct injury prevention methods and enhance the support and education of youth coaches in this regard.

  17. Measuring perceptions related to e-cigarettes: Important principles and next steps to enhance study validity. (United States)

    Gibson, Laura A; Creamer, MeLisa R; Breland, Alison B; Giachello, Aida Luz; Kaufman, Annette; Kong, Grace; Pechacek, Terry F; Pepper, Jessica K; Soule, Eric K; Halpern-Felsher, Bonnie


    Measuring perceptions associated with e-cigarette use can provide valuable information to help explain why youth and adults initiate and continue to use e-cigarettes. However, given the complexity of e-cigarette devices and their continuing evolution, measures of perceptions of this product have varied greatly. Our goal, as members of the working group on e-cigarette measurement within the Tobacco Centers of Regulatory Science (TCORS) network, is to provide guidance to researchers developing surveys concerning e-cigarette perceptions. We surveyed the 14 TCORS sites and received and reviewed 371 e-cigarette perception items from seven sites. We categorized the items based on types of perceptions asked, and identified measurement approaches that could enhance data validity and approaches that researchers may consider avoiding. The committee provides suggestions in four areas: (1) perceptions of benefits, (2) harm perceptions, (3) addiction perceptions, and (4) perceptions of social norms. Across these 4 areas, the most appropriate way to assess e-cigarette perceptions depends largely on study aims. The type and number of items used to examine e-cigarette perceptions will also vary depending on respondents' e-cigarette experience (i.e., user vs. non-user), level of experience (e.g., experimental vs. established), type of e-cigarette device (e.g., cig-a-like, mod), and age. Continuous formative work is critical to adequately capture perceptions in response to the rapidly changing e-cigarette landscape. Most important, it is imperative to consider the unique perceptual aspects of e-cigarettes, building on the conventional cigarette literature as appropriate, but not relying on existing conventional cigarette perception items without adjustment. Copyright © 2017 Elsevier Ltd. All rights reserved.

  18. Getting Competitive: Competitive Intelligence Is a Smart next Step for Information Pros (United States)

    Correia, Cynthia Cheng


    Competitive Intelligence (CI) has become an attractive concept for Library and Information Science professionals, as information and research functions have become commoditized by end users, and financial, competitive, and performance pressures increase the need to demonstrate value. In the current competitive and cost-cutting environment,…

  19. A model for quality of life measures in patients with dementia: Lawron's next step

    NARCIS (Netherlands)

    Jonker, C.; Gerritsen, D.L.; Bosboom-van der Hurk, P.R.


    The introduction of drugs that are claimed to improve cognitive function and activities of daily living in patients with Alzheimer's disease raises the question of whether these drugs also influence dementia patients' quality of life (QOL). We describe a hierarchic model of QOL of dementia patients,

  20. Evaluation of an Electrostatic Dust Removal System with Potential Application in Next-Step Fusion Devices (United States)

    Friesen, F. Q. L.; John, B.; Skinner, C. H.; Roquemore, L.; Calle, C.


    The ability to manage inventories of dust will become increasingly important as fusion devices become larger and operate with a higher duty cycle. An electrostatic dust conveyor, originally developed to remove dust from solar panels on planetary rovers, has been tested for applicability to fusion devices. It consists of a spiral pattern of three indium tin oxide traces on a glass substrate that is biased to produce a surface electrostatic traveling wave. A digital microscope measured the particle size distribution before and after operation. The transport efficiency for different particle sizes of tungsten, carbon from an NSTX tile, fine glass spheres, and sand versus given different pre-charge voltages, pre-charge durations, driving amplitudes, and driving frequencies, will be presented. The results will be used to determine the optimal settings for a dust conveyor demonstration on NSTX.

  1. Distributed Experiments in Design Sciences, a Next Step in Design Observation Studies?

    CERN Document Server

    Kriesi, Carlo; Aalto-Setala, Laura; Anvik, Anders; Balters, Stephanie; Baracchi, Alessia; Jensen, Bisballe Matilde; Bjorkli, Leif Erik; Buzzaccaro, Nicolo; Cortesi, Dario; D'Onghia, Francesco; Dosi, Clio; Franchini, Giulia; Fuchs, Matt; Gerstenberg, Achim; Hansen, Erik; Hiekkanen, Karri Matias; Hyde, David; Ituarte, Inigo; Kalasniemi, Jani; Kurikka, Joona; Lanza, Irene; Laurila, Anssi; Lee, Tik Ho; Lonvik, Siri; Mansikka-Aho, Anniina; Nordberg, Markus; Oinonen, Paivi; Pedrelli, Luca; Pekuri, Anna; Rane, Enna; Reime, Thov; Repokari, Lauri; Ronningen, Martin; Rowlands, Stephanie; Sjoman, Heikki; Slattsveen, Kristoffer; Strachan, Andy; Stromstad, Kirsti; Suren, Stian; Tapio, Peter; Utriainen, Tuuli; Vignoli, Matteo; Vijaykumar, Saurabh; Welo, Torgeir; Wulvik, Andreas


    This paper describes and proposes a new method for conducting globally distributed design research. Instead of using e.g. a software we tried out a completely analogue approach: Five carefully prepared packages, containing all the necessary materials and instructions for a design challenge, were sent out to supervisors in Norway, Finland, Italy, and Australia. These local supervisors then conducted the egg-drop exercise with students that are part of an international course held at CERN. As the task is conducted according to a previously tested protocol, the results gathered with this new method can then be benchmarked with this available data. This new approach to globally conducted engineering design activities avoids local bias and enables for gathering large amounts of diverse data points. One can also think of a research community where every member can send out one experiment per year and, in return, receives data points from across the world. Based on the feedback from the supervisors we can say that ...

  2. Adaptive Pathways: Possible Next Steps for Payers in Preparation for Their Potential Implementation

    Directory of Open Access Journals (Sweden)

    Patricia Vella Bonanno


    Full Text Available Medicines receiving a conditional marketing authorization through Medicines Adaptive Pathways to Patients (MAPPs will be a challenge for payers. The “introduction” of MAPPs is already seen by the European Medicines Agency (EMA as a fait accompli, with payers not consulted or involved. However, once medicines are approved through MAPPs, they will be evaluated for funding by payers through different activities. These include Health Technology Assessment (HTA with often immature clinical data and high uncertainty, financial considerations, and negotiations through different types of agreements, which can require monitoring post launch. Payers have experience with new medicines approved through conditional approval, and the fact that MAPPs present additional challenges is a concern from their perspective. There may be some activities where payers can collaborate. The final decisions on whether to reimburse a new medicine via MAPPs will have more variation than for medicines licensed via conventional processes. This is due not only to increasing uncertainty associated with medicines authorized through MAPPs but also differences in legal frameworks between member states. Moreover, if the financial and side-effect burden from the period of conditional approval until granting full marketing authorization is shifted to the post-authorization phase, payers may have to bear such burdens. Collection of robust data during routine clinical use is challenging along with high prices for new medicines during data collection. This paper presents the concept of MAPPs and possible challenges. Concerns and potential ways forward are discussed and a number of recommendations are presented from the perspective of payers.

  3. Somali Piracy: The Next Iteration

    Directory of Open Access Journals (Sweden)

    Peter Lehr


    Full Text Available The article describes the escalation of acts of maritime piracy emanating from the coast of Somalia, comparing them to the wave of aerial hijackings in the 1960s and 1970s in terms of demands, including political demands. The advantages for the pirates to gang up with land-based al-Shabaab terrorists are discussed and likely developments sketched.

  4. Microanalytic Assessment of Self-Regulated Learning During Clinical Reasoning Tasks: Recent Developments and Next Steps. (United States)

    Cleary, Timothy J; Durning, Steven J; Artino, Anthony R


    Helping medical educators obtain and use assessment data to assist medical students, residents, and physicians in reducing diagnostic errors and other forms of ineffective clinical practice is of critical importance. Self-Regulated Learning-Microanalytic Assessment and Training is an assessment-to-intervention framework designed to address this need by generating data about trainees' strategic processes (e.g., focusing on clinical task procedures), regulatory processes (e.g., planning how to do a task), and motivational processes (e.g., increasing confidence for performing a task) as they perform clinical activities. In this article, the authors review several studies that have used an innovative assessment approach, called self-regulated learning (SRL) microanalysis, to generate data about how trainees regulate their thinking and actions during clinical reasoning tasks. Across the studies, initial findings revealed that medical students often do not exhibit strategic thinking and action during clinical reasoning practice tasks even though some regulatory processes (e.g., planning) are predictive of important medical education outcomes. Further, trainees' motivation beliefs, strategic thinking, and self-evaluative judgments tend to shift rapidly during clinical skills practice and may also vary across different parts of a patient encounter. Collectively, these findings underscore the value of dynamically assessing trainees' SRL as they complete clinical tasks. The findings also set the stage for exploring how medical educators can best use SRL microanalytic assessment data to guide remedial practices and the provision of feedback to trainees. Implications and future research directions for connecting assessments to intervention in medical education are discussed.

  5. Skill Transfer and Virtual Training for IND Response Decision-Making: Project Summary and Next Steps (United States)


    Lincoln Laboratory MASSACHUSETTS INSTITUTE OF TECHNOLOGY LEXINGTON, MASSACHUSETTS Technical Report 1209 Skill Transfer and Virtual ...specifically authorized by the U.S. Government may violate any copyrights that exist in this work. Skill Transfer and Virtual Training for IND Response... Commission DO TheiOc~ ome.ll!J tlank you for your ,.lp In thJn.klng 1~ !heir tom’Tluntt(s nHds. el’ld say tn.y wf$h tMy had the buOget IO<IOI~YOU CUt\\IU I

  6. Neutron imaging on the VR-1 reactor (United States)

    Crha, J.; Sklenka, L.; Soltes, J.


    Training reactor VR-1 is a low power research reactor with maximal thermal power of 1 kW. The reactor is operated by the Faculty of Nuclear Science and Physical Engineering of the Czech Technical University in Prague. Due to its low power it suits as a tool for education of university students and training of professionals. In 2015, as part of student research project, neutron imaging was introduced as another type of reactor utilization. The low available neutron flux and the limiting spatial and construction capabilities of the reactor's radial channel led to the development of a special filter/collimator insertion inside the channel and choosing a nonstandard approach by placing a neutron imaging plate inside the channel. The paper describes preliminary experiments carried out on the VR-1 reactor which led to first radiographic images. It seems, that due to the reactor construction and low reactor power, the neutron imaging technique on the VR-1 reactor is feasible mainly for demonstration or educational and training purposes.

  7. Zephyr - the next generation prediction

    DEFF Research Database (Denmark)

    Giebel, G.; Landberg, L.; Nielsen, Torben Skov


    Two of the most successful short-term prediction models (and the only ones in operational use at utilities) are going to be merged into one: the Risø model, developed by Landberg and the Wind Power Prediction Tool WPPT, developed at the Department of Mathematical Modelling IMM of the Danish...... Technical University. This paper will describe a new project funded by the Danish Ministry of Energy where the largest Danish utilities (Elkraft, Elsam, Eltra and SEAS) are participating. Two advantages can be achieved by combining the effort: The software architecture will be state-of-the-art, using...... the Java2TM platform and Enterprise Java Beans technology, and it will ensure that the best forecasts are given on all prediction horizons from the short range (0-9 hours) to the long range (36-48 hours). This is because the IMM approach uses online data and advanced statistical methods, which...

  8. Lasers: The next fifty years

    NARCIS (Netherlands)

    Kärtner, Franz; Pollnau, Markus; Ueda, Ken-ichi; van Driel, Henry


    This year marks the 50th anniversary of the laser — the first coherent radiation source in the optical domain. This anniversary of this historic development is being celebrated this year through “Laserfest‿ in which the Optical Society is a major partner. The laser enabled a straightforward

  9. Campus Governance - The Next Decade. (United States)

    Hodgkinson, Harold L.

    In our society, the majority of the population is under 25, and the value orientation of this group is replacing the old one of the Protestant Ethic. Work is deemphasized and fulfillment stressed; joy is substituted for guilt. The campus has, however, not moved an iota toward this new ethic, and much of student protest revolves around that. During…

  10. The next generation is here

    CERN Multimedia


    This year the CERN Accelerator School returned to Austria after an interval of ten years and organized its Basic Accelerator Physics course together with the Austrian Academy of Sciences (HEPHY) in Baden, near Vienna, from 12-24 September, 2004. The Introductory level course is particularly important since, for most of the participants, it is the first opportunity to discover the various aspects of accelerator physics. The school was a resounding success with 95 students of more than 20 different nationalities attending. This particularly high attendance is very satisfying and confirms the strong interest in accelerator physics among young scientists. Feedback from the students praised the expertise of the lecturers, the high standard of the lectures as well as the pleasant environment and excellent organization. In addition to the intensive work programme of 33 lectures, three seminars, five tutorials, a poster session where students could present their own work, and seven hours of guided and private study,...

  11. Next step in antibiotic stewardship: Pharmacist-provided penicillin allergy testing. (United States)

    Gugkaeva, Z; Crago, J S; Yasnogorodsky, M


    Penicillin allergy limits therapeutic options for patients but often disappears over time, leaving patients erroneously labelled allergic and leading to the utilization of broad-spectrum and more expensive antibiotics. Penicillin allergy can be effectively assessed via skin testing. To improve patient access to penicillin allergy testing by implementing a pharmacist-provided service in a hospital setting. Beta-lactams remain a mainstream therapy for many infections due to their effectiveness, low side effects and affordability. Typically, patient access to penicillin allergy testing is limited by the availability of allergy specialists, who traditionally perform such testing. A pharmacist-provided penicillin allergy testing service was implemented at our hospital in 2015 and became a powerful antibiotic stewardship tool. Removing penicillin allergy from patient profiles significantly expanded therapeutic options, expedited discharges and reduced costs of care. Pharmacists can expand patient access to penicillin allergy testing. Pharmacist-provided penicillin allergy testing permitted optimized antibiotic treatment and expedited discharges. © 2017 John Wiley & Sons Ltd.

  12. The next generation of PCPs

    Energy Technology Data Exchange (ETDEWEB)

    Petten, P.; Mitskopoulos, M. [Kudu Pumps, Calgary, AB (Canada)


    Kudu Pump has developed a progressing cavity pump (PCP) which incorporates unique equipment features and designs for multiple applications and well conditions. This presentation provided details of current thermal projects where the proven artificial lift alternative has demonstrated distinct advantages. The projects include 14 steam assisted gravity drainage (SAGD) wells in the Athabasca deposit, 1 cyclic steam stimulation (CSS) well in the Cold Lake deposit, and 1 CSS well in the Peace River deposit. Each case study was presented with reference to installation, performance and lessons learned. The operation procedures were described in terms of standard completion, the drive system, and the patented high temperature seal. The PCP has undergone developmental testing and product improvement. Additional projects involving the use of the PCP are planned for 2008 for the Athabasca, Cold Lake and Peace River deposits, plus an additional steam flood project in California. tab., figs.

  13. TRAC PAC : the next generation (United States)


    The Transportation and Civil Engineering (TRAC) PAC is a toolkit of instructional aids originally built in 1994 to attract middle and high school students to the transportation field. Since that time, users have noted difficulties arising from the PA...

  14. Is nitrogen the next carbon? (United States)

    Battye, William; Aneja, Viney P.; Schlesinger, William H.


    Just as carbon fueled the Industrial Revolution, nitrogen has fueled an Agricultural Revolution. The use of synthetic nitrogen fertilizers and the cultivation of nitrogen-fixing crops both expanded exponentially during the last century, with most of the increase occurring after 1960. As a result, the current flux of reactive, or fixed, nitrogen compounds to the biosphere due to human activities is roughly equivalent to the total flux of fixed nitrogen from all natural sources, both on land masses and in the world's oceans. Natural fluxes of fixed nitrogen are subject to very large uncertainties, but anthropogenic production of reactive nitrogen has increased almost fivefold in the last 60 years, and this rapid increase in anthropogenic fixed nitrogen has removed any uncertainty on the relative importance of anthropogenic fluxes to the natural budget. The increased use of nitrogen has been critical for increased crop yields and protein production needed to keep pace with the growing world population. However, similar to carbon, the release of fixed nitrogen into the natural environment is linked to adverse consequences at local, regional, and global scales. Anthropogenic contributions of fixed nitrogen continue to grow relative to the natural budget, with uncertain consequences.

  15. Ethics for the next Generation (United States)

    Langlais, Philip J.


    Reports of gross misconduct like plagiarism and the falsification and fabrication of data in the hallowed halls of academe and research laboratories are becoming increasingly common in the US. Researchers suggest that the higher education institutions need to become more involved than they have been on educating graduate students about ethical…

  16. Algeria: The Next Fundamentalist State? (United States)


    ARCO , suggesting a desire to move ahead in privatization in certain areas. While the energy sector is probably a highly attractive field of...within the state structure. THE "SANT’ EGIDIO" BREAKTHROUGH A new variable entered the Algerian political scene with two extraor - dinary meetings

  17. A microfluidic device for preparing next generation DNA sequencing libraries and for automating other laboratory protocols that require one or more column chromatography steps. (United States)

    Tan, Swee Jin; Phan, Huan; Gerry, Benjamin Michael; Kuhn, Alexandre; Hong, Lewis Zuocheng; Min Ong, Yao; Poon, Polly Suk Yean; Unger, Marc Alexander; Jones, Robert C; Quake, Stephen R; Burkholder, William F


    Library preparation for next-generation DNA sequencing (NGS) remains a key bottleneck in the sequencing process which can be relieved through improved automation and miniaturization. We describe a microfluidic device for automating laboratory protocols that require one or more column chromatography steps and demonstrate its utility for preparing Next Generation sequencing libraries for the Illumina and Ion Torrent platforms. Sixteen different libraries can be generated simultaneously with significantly reduced reagent cost and hands-on time compared to manual library preparation. Using an appropriate column matrix and buffers, size selection can be performed on-chip following end-repair, dA tailing, and linker ligation, so that the libraries eluted from the chip are ready for sequencing. The core architecture of the device ensures uniform, reproducible column packing without user supervision and accommodates multiple routine protocol steps in any sequence, such as reagent mixing and incubation; column packing, loading, washing, elution, and regeneration; capture of eluted material for use as a substrate in a later step of the protocol; and removal of one column matrix so that two or more column matrices with different functional properties can be used in the same protocol. The microfluidic device is mounted on a plastic carrier so that reagents and products can be aliquoted and recovered using standard pipettors and liquid handling robots. The carrier-mounted device is operated using a benchtop controller that seals and operates the device with programmable temperature control, eliminating any requirement for the user to manually attach tubing or connectors. In addition to NGS library preparation, the device and controller are suitable for automating other time-consuming and error-prone laboratory protocols requiring column chromatography steps, such as chromatin immunoprecipitation.

  18. Lyme disease: the next decade

    Directory of Open Access Journals (Sweden)

    Raphael B Stricker


    Full Text Available Raphael B Stricker, Lorraine JohnsonInternational Lyme and Associated Diseases Society, Bethesda, MD, USAAbstract: Although Lyme disease remains a controversial illness, recent events have created an unprecedented opportunity to make progress against this serious tick-borne infection. Evidence presented during the legally mandated review of the restrictive Lyme guidelines of the Infectious Diseases Society of America (IDSA has confirmed the potential for persistent infection with the Lyme spirochete, Borrelia burgdorferi, as well as the complicating role of tick-borne coinfections such as Babesia, Anaplasma, Ehrlichia, and Bartonella species associated with failure of short-course antibiotic therapy. Furthermore, renewed interest in the role of cell wall-deficient (CWD forms in chronic bacterial infection and progress in understanding the molecular mechanisms of biofilms has focused attention on these processes in chronic Lyme disease. Recognition of the importance of CWD forms and biofilms in persistent B. burgdorferi infection should stimulate pharmaceutical research into new antimicrobial agents that target these mechanisms of chronic infection with the Lyme spirochete. Concurrent clinical implementation of proteomic screening offers a chance to correct significant deficiencies in Lyme testing. Advances in these areas have the potential to revolutionize the diagnosis and treatment of Lyme disease in the coming decade.Keywords: Lyme disease, Borrelia burgdorferi, L-forms, cysts, biofilms, proteomics

  19. Lyme disease: the next decade (United States)

    Stricker, Raphael B; Johnson, Lorraine


    Although Lyme disease remains a controversial illness, recent events have created an unprecedented opportunity to make progress against this serious tick-borne infection. Evidence presented during the legally mandated review of the restrictive Lyme guidelines of the Infectious Diseases Society of America (IDSA) has confirmed the potential for persistent infection with the Lyme spirochete, Borrelia burgdorferi, as well as the complicating role of tick-borne coinfections such as Babesia, Anaplasma, Ehrlichia, and Bartonella species associated with failure of short-course antibiotic therapy. Furthermore, renewed interest in the role of cell wall-deficient (CWD) forms in chronic bacterial infection and progress in understanding the molecular mechanisms of biofilms has focused attention on these processes in chronic Lyme disease. Recognition of the importance of CWD forms and biofilms in persistent B. burgdorferi infection should stimulate pharmaceutical research into new antimicrobial agents that target these mechanisms of chronic infection with the Lyme spirochete. Concurrent clinical implementation of proteomic screening offers a chance to correct significant deficiencies in Lyme testing. Advances in these areas have the potential to revolutionize the diagnosis and treatment of Lyme disease in the coming decade. PMID:21694904

  20. Planning for the next generation. (United States)

    Valdes, C


    Poverty, illiteracy, and lack of government commitment or ability to solve social ills translates into rapid population growth in central American isthmus countries: El Salvador, Guatemala, Honduras, Nicaragua, and even Costa Rica and Panama. The social conditions in Panama and Costa Rica lead to better family planning (FP). Educational and health resources are lacking for the rest of the countries. High birth and infant mortality rates and political unrest contribute to the total fertility rate in Honduras of 5.4 children/woman, the growth rate in Nicaragua of 3.4%, and the contraceptive use rate f 23% among married women in Guatemala and 27% in Nicaragua. The population of El Salvador is expected to double to 11 million in 25 years. FP efforts are being threatened in Costa Rica and Panama due to the doubling of the poor population since 1983 and the cutbacks in government spending for FP. For every North American woman who dies of maternal mortality, 134 die in Central America. Today the power of the Catholic Church is offset by the government population policy and programs of private organizations. Improvements have been made in Costa Rica in maternal and child health services and FP; life expectancy for children has increased 22 years in Honduras; and total fertility is under 3 children/woman in Panama. Private organizations have taken the lead in FP programs. Although population policy is part of development, national governments still lack the political will to solve the problems of access to basic health care and education, better water and sewers, and good food and jobs. The civil wars in Nicaragua and El Salvador and insurgency in Guatemala have diverted resources for health care, housing, and education. The gross national products in each of these countries is US$910/person/year. FP funds must compete with education, health care, and other basic services for government spending. The systems for FP have been established, but the political will is missing

  1. The Next-Generation Infrastructure. (United States)

    Lightfoot, Ed; Ihrig, Weldon


    Describes a planning framework that provides the technical foundation necessary to support Web-based relationships and applications in higher education. The framework enables delivery of information, tools, and services to all of a university's constituents. (EV)

  2. Beware the next big thing. (United States)

    Birkinshaw, Julian


    Innovative management ideas that bubble up in other companies pose a perennial quandary for leaders: Should you attempt to borrow new ideas, and if so, which ones and how? Even the most promising practices can be disastrous if they're transplanted into the wrong company, writes Julian Birkinshaw of London Business School. Broadly speaking, there are two ways to borrow from innovative companies, he argues. The first, observe and apply, is the most commonly used approach for adopting new management ideas. It can and does work well, but only under Limited sets of circumstances: when the observed practice easily stands alone or involves just a small constellation of supporting behaviors (think of GE's well-regarded succession-planning process) and when a company's management model or way of thinking is very similar to the originator's (think of two software firms that both use the Agile development approach). The second method is to extract a management practice's essential principle-its underlying logic-and ask a series of questions to determine if it is right for your firm, including: How is your company different from the originating firm? Are the goals of the practice important to your organization? Many management innovations are launched with great fanfare, only to fade in popularity. With careful analysis, you can avoid falling prey to this hype cycle. And even if it turns out that a borrowed idea isn't right for you, the analysis will help you better understand your own management models and sharpen your practices.

  3. Game theory : The next stage

    NARCIS (Netherlands)

    van Damme, E.E.C.


    This paper surveys some recent developments in (non-cooperative) game theory and provides an outlook on the near future of that theory. In particular, attention is focused on the limitations inherent in normative game theory and on attempts to construct a behavioral version of the theory that

  4. Libraries: The Next Hundred Years

    Directory of Open Access Journals (Sweden)

    Brett Bonfield


    Full Text Available Usually when we discuss the future of libraries, we’re talking about a year or two in the future, maybe up to ten. We look at forward-thinking libraries like NC State, or Darien Public Library in Connecticut, or maybe the initiative Nate Hill is helping to lead in Chattanooga. But for this article, I’m interested in [...

  5. Aesthetics for the next millennium. (United States)

    Yellin, S A


    The approach of a new millenium provides us, as rhinoplasty surgeons, the opportunity to reflect on where we are and where we are going. Aesthetically, there are several trends that are evident today. The first is the desire for a natural, unoperated appearance to the final rhinoplasty result. Second, is that our patient population continues to be more racially diverse; Caucasian normative standards of facial analysis are no longer sufficient. What is required is a broader understanding of ethnically specific facial features. Third, the standard values of facial and nasal analysis are derived from population means. If we desire to create beauty, these standards may not be adequate. Beauty is an ill-defined concept that is obvious to the observer and recognized cross-culturally, however, it is difficult to quantify. To consistently achieve beautiful rhinoplasty results, we must start with an understanding of what our aesthetic ideals should be. This has yet to be satisfactorily defined for all racial groups and remains a challenge for the future.

  6. Fan Cart: The Next Generation (United States)

    Lamore, Brian


    For years the fan cart has provided physics students with an excellent resource for exploring fundamental mechanics concepts such as acceleration, Newton's laws, impulse, momentum, work-energy, and energy conversions. "The Physics Teacher" has even seen some excellent do-it-yourself (DIY) fan carts and activities. If you are interested…

  7. Hypercars: The next industrial revolution (United States)

    Lovins, Amory B.; Barnett, John W.; Lovins, L. Hunter


    The auto industry -- one-seventh of the GNP, and the highest expression of the Iron Age -- is about to trigger the biggest transformation in industrial structure since the microchip. Ultralight cars molded from net-shape advanced composites can be several-fold lighter than present steel cars, yet safer, sportier, and more comfortable, durable, and beautiful. Modern hybrid-electric drives boost efficiency approximately 1.3-1.5x in heavy steel cars, but approximately 5-20x in ultralight, very slippery plafforms. Synergistically combined into ultralight-hybrid 'hypercars,' these elements can yield state-of-the-shelf family cars that average 150-300+ mi/gal -- twice that with state-of-the-art technologies -- yet can also be superior in all other respects, probably including cost: carbon-fiber monocoques can actually be cheaper to mass-produce that steel unibodies. Designing cars more like aircraft and less like tanks requires not only an approximately 400-500 kg curb mass and very low air and road drag, but also an aerospace philosophy of engineering integration. Mass, cost, and complexity turn out to compound with heavy hybrids but to decompound with ultralight hybrids, owing partly to radical simplification. Excellent aerodynamics, preferable including advanced techniques for passive boundary-layer control, will be the key to successful design integration. Transforming automaking is a competitive and environmental imperative, could form the nucleus of a green industrial Renaissance, and would enhance national security by, among other things, saving as much oil as OPEC now extracts. However, this transformation faces serious cultural barriers. For example, hypercars will be more like computers with wheels than like cars with chips -- they'll have an order of magnitude more code than today's cars -- but Detroit is not a software culture. Just the transition from stamped and welded steel to integrated and adhesive-joined synthetics is difficult enough. Nonetheless

  8. Holography: The Next Disruptive Technology (United States)


    rapidly changing technological advances in holography and how it could transform the Army’s in-theater tactics as well as training and...Approved for public release; distribution is unlimited. 2 Part I of this report will focus on materials and chemistries investigated for these...Defense Advanced Research Projects Agency partnered with Zebra Imaging to produce a prototype of the ZScape Motion Display for a real-time streaming

  9. The next step in Europe's climate action. Setting targets for 2030. Reviving the EU emissions trading system and bringing EU greenhouse gas emissions on a 2C track. Policy brief

    Energy Technology Data Exchange (ETDEWEB)

    Hoehne, N.; Gilbert, A.; Hagemann, M.; Fekete, H.; Lam, Long; De Vos, R. [Ecofys, Utrecht (Netherlands)


    This paper explains how setting 2030 targets will reinvigorate the ETS and will put EU emissions on track to limit global temperature increase below two degrees Celsius (2C). This paper describes four key findings for EU policymakers engaged in preparing EU energy and climate measures for 2030 and for the longer term. The European Commission estimates that by 2020, the companies participating in the ETS will have accumulated a surplus of 1.5 to 2.3 billion allowances, which may be banked and used beyond 2020. This is about the same size as the annual emissions budget of ETS companies (just below 2 billion tonnes). Applying equity principles to the global distribution of efforts in reaching the 2C goal, an indicative 'fair' EU contribution would be a reduction of EU greenhouse gas emissions by around 49% (median of a full range from 39 to 79%) by 2030 compared to 1990 levels. The 2030 targets can be set in a way to also accommodate the surplus expected until 2020. If the entire surplus of allowances from the ETS were to be used after 2020, the 2030 target has to become around 7 percentage points more stringent to compensate for that. Alternatively, the trajectory of the target from 2021 to 2030 could be set to compensate for the surplus. In addition, a more ambitious trajectory towards 2030 would cast its shadow on the mitigation in the period 2013-2020. It would strengthen the ETS, in conjunction with any other ETS recalibration options such as shifting the auctioning ('backloading') or cancelling allowances before 2020.

  10. The first Swedish nuclear reactor - from technical prototype to scientific instrument; Sveriges foersta kaernreaktor - fraan teknisk prototyp till vetenskapligt instrument

    Energy Technology Data Exchange (ETDEWEB)

    Fjaestad, M. [Royal Inst. of Tech., Stockholm (Sweden). Dept. of History of Science and Technology


    The first Swedish reactor R1, constructed at the Royal Inst. of Technology in Stockholm, went critical in July 1954. This report presents historical aspects of the reactor, in particular about the reactor as a research instrument and a centre for physical science. The tensions between its role as a prototype and a step in the development of power reactors and that as a scientific instrument are especially focused.

  11. Health, comfort, energy use and sustainability issues related to the use of biobased building materials : to what extent are the effects supported by science and data? : what are next steps to take?


    Visser, de, J.A.G.M.; Wijk, van, C.A.P.; Voort, van der, M.P.J.


    With the exception of wood, the use of natural (biobased) materials (based on hemp, flax, straw or other natural resources) is still limited. Nevertheless, many benefits are attributed to these materials in terms of a healthier and more comfortable indoor climate. Other potential benefits of natural insulation materials that are often mentioned are energy savings and reduced environmental impact. This report focuses on the<