WorldWideScience

Sample records for tgd weekly status

  1. WBDOC Weekly Workload Status Report

    Data.gov (United States)

    Social Security Administration — Weekly reports of workloads processed in the Wilkes Barre Data Operation Center. Reports on quantities of work received, processed, pending and average processing...

  2. Nutritional status of twice and thrice-weekly hemodialysis patients with weekly Kt/V > 3.6.

    Science.gov (United States)

    Supasyndh, Ouppatham; Satirapoj, Bancha; Seenamngoen, Sudarat; Yongsiri, Somchai; Choovichian, Punbuppa; Vanichakarn, Supat

    2009-05-01

    Multiple lines of evidence have indicated that the dose of hemodialysis (HD) affects patient outcome. According to K-DOQI, daily spKt/V > 1.2 predicts the morbidity and mortality among thrice-weekly HD. However in developing countries, about three-fourths of end stage renal disease patients undergo twice-weekly HD. No data studied the outcome and nutritional status between twice- and thrice-weekly HD patients. To compare the nutritional parameters in twice- and thrice-weekly HD patients who had weekly Kt/V > 3.6. The cross-sectional study was performed in the HD unit of the National Kidney Foundation of Thailand. One hundred and forty two informed consent HD patients were enrolled in the present study. Nutritional status was evaluated following a HD treatment by bioelectrical impedance analysis. All patients were interviewed for three-day food record and data were analyzed by Inmucal software program. Sixty patients had thrice-weekly HD and 82 patients were on twice-weekly HD. The characteristics and duration of dialysis of both groups were similar except age. Duration of dialysis in thrice-weekly HD group was 82.64 +/- 50 82 and twice-weekly HD group was 68.92 +/- 31.49 months. The mean age of the thrice-weekly HD group and twice-weekly HD group patients were 47.78 +/- 9.89 and 41.63 +/- 10.47 years, respectively (p nutrition parameters except daily energy intake which was lower in the thrice-weekly HD group than twice-weekly HD group (19.21 +/- 6.42 vs. 25.02 +/- 7.70 kcal/kg/day, p patients with delivered weekly Kt/V > 3.6, nutritional status of patients undergoing twice-weekly HD are not different from that of thrice-weekly HD patients. Higher energy intake in twice-weekly HD patients might be the explanation.

  3. Effect of once a week endurance exercise on fitness status in sedentary subjects.

    Science.gov (United States)

    Hiruntrakul, Ashira; Nanagara, Ratanavadee; Emasithi, Alongkot; Borer, Katarina T

    2010-09-01

    To study whether 3-months aerobic exercise training at moderate intensity once a week can increase fitness status in healthy sedentary young men. Randomized controlled study was performed in 37 sedentary young men, 18 to 25 years old. The exercise group (19) was assigned to work on bicycle ergometry at 60% of maximal effort, once a week for 12 weeks. The control group (18) lived a normal life style. Before and after training, aerobic fitness (VO2(max)), resting heart rate, lipid profile, and isokinetic power and strength of shoulder and knee were evaluated. In the exercise group, there was a significant increase in most fitness parameters compared with control, VO2(max) (19.7%), isokinetic power and strength of shoulder and knee (14.9%), and resting heart rate decreased (7.4%). Moderate-intensity training once a week for at least 12 weeks was sufficient to increase aerobic fitness in sedentary young men. This low frequency of exercise training may be used to encourage sedentary individuals for more compliance with physical activity.

  4. [Neonatal vitamin D status and calcium-phosphorus homeostasis in the third week of life].

    Science.gov (United States)

    Czech-Kowalska, Justyna; Dobrzanska, Anna; Janowska, Joanna; Pleskaczynska, Agata; Niezgoda, Anna; Golkowska, Malgorzata; Witwicki, Jacek; Gruszfeld, Dariusz; Jedrzejczak, Anna

    2004-01-01

    Assessment of vitamin D status and calcium -phosphorus homeostasis in term newborns before routine supplementation. Calcidiol (25OHD), calcium, phosphorus and alkaline phosphatase in serum and Ca (urine)/creatinine (urine) ratio (mg/mg), P (urine)/creatinine (urine) ratio (mg/mg) and tubular phosphate reabsorption rate (TRP= [1-(P(urine) / P(serum). creatinine serum/urine)].100%) in 3rd week of life in 56 appropriate for gestational age term neonates was measured. First group contains 35 newborns (62.5%) with normal 25OHD values and second group 21 newborns (37.5%) with hypovitaminosis D (25OHD 0.05). There were 51.43% breastfed newborns in group one and 85.71% in group two (p=0.009). Median 25OHD concentration in breastfed newborns was 11.2 ng/ml and 18.5 ng/ml in formula fed babies (p=0.017). There were no statistical differences between groups in calcium (2.44 vs. 2.41 mmol/l), phosphorus (2.27 vs. 2.22 mmol/l) and alkaline phosphatase (261 vs. 266 U/L) blood concentration and Ca (urine)/creatinine (urine) ratio (0,34 vs. 0,25mg/mg) and TRP (86% vs. 88%) (p>0.05). The P (urine) /creatinine (urine) ratio in the first group was 2.3mg/mg and 1.42 mg/mg in the second group (p=0.048). Neonatal vitamin D stores in the 3rd week of life are not more dependent on maternal vitamin D supplementation during pregnancy. Breastfed infants are at greater risk of hypovitaminosis D than formula fed infants, therefore earlier vitamin D supply should be considered. The hypovitaminosis D has no influence on basic parameters of Ca-P homeostasis in the 3rd week of life.

  5. Effects of three times weekly eight-hour nocturnal hemodialysis on volume and nutritional status.

    Science.gov (United States)

    Demirci, Cenk; Ozkahya, Mehmet; Demirci, Meltem Sezis; Asci, Gulay; Kose, Timur; Colak, Taskin; Duman, Soner; Toz, Huseyin; Ergin, Pinar; Adam, Siddik Momin; Ok, Ercan

    2013-01-01

    This prospective cohort study compared the changes in body water composition and nutritional parameters measured with multifrequency bioimpedance analysis between 8-hour three times weekly nocturnal hemodialysis (NHD) and 4-hour conventional hemodialysis (CHD) patients. 55 patients on CHD and 57 patients on NHD were included in the study. Multifrequency bioimpedance analysis was performed at baseline and at the 12th month. The primary outcomes of the study were changes in extracellular water (ECW), fat mass, dry lean mass and phase angle. Secondary outcomes of the study included changes in blood pressure and biochemical parameters related to nutrition and inflammation. ECW/height values decreased in the NHD group, while they increased in the CHD group. Fat mass, dry lean mass, and serum albumin increased and high sensitive CRP decreased in the NHD group but did not change in the CHD group. When changes in parameters from baseline to the 12th month between the groups were compared, NHD was associated with improvement in volume parameter including ECW/height (difference -0.44 l/m, p nutritional status. Copyright © 2013 S. Karger AG, Basel.

  6. Fluvial River Regime in Disturbed River Systems: A Case Study of Evolution of the Middle Yangtze River in Post-TGD (Three Gorges Dam), China

    NARCIS (Netherlands)

    Zhao, G.; Lu, J; Visser, P.J.

    2015-01-01

    The fluvial river is a kind of open system that can interact with its outside environments and give response to disturbance from outside on the earth. It can adjust itself to the disturbances outside the system and reflects new characteristics in the process of reaching a new equilibrium. The TGD

  7. Climate-informed flood frequency analysis based on Bayesian theory and teleconnection for the Three Gorges Dam (TGD)

    Science.gov (United States)

    DONG, Q.; Zhang, X.; Lall, U.; Sang, Y. F.; Xie, P.

    2017-12-01

    With the current global climate changing and human activities intensifying, the uncertainties and danger of floods increased significantly. However, the current flood frequency analysis is still based on the stationary assumption. This assumption not only limits the benefits of the water conservancy projects, but also brings hazard because it ignores the risk of flooding under climate change. In this paper, we relax the stationary hypothesis in the flood frequency analysis model based on the teleconnection and use the intrinsic relation of flood elements to improve the annual flood frequency results by Bayesian inference approaches. Daily discharges of the the Three Gorges Dam(TGD) in 1953-2013 years are used as an example. Firstly, according to the linear correlation between the climate indices and the distribution parameters, the prior distributions of peak and volume are established with the selected large scale climate predictors. After that, by using the copula function and predictands, the conditional probability function of peak and volume is obtained. Then, the Bayesian theory links the prior distributions and conditional distributions and get the posterior distributions. We compare the difference under different prior distributions and find the optimal flood frequency distribution model. Finally, we discuss the impact of dynamic flood frequency analysis on the plan and management of hydraulic engineering. The results show that compared with the prior probability, the posterior probability considering the correlation of the flood elements is more accurate and the uncertainty is smaller. And the dynamic flood frequency model has a great impact on the management of the existing hydraulic engineering, which can improve the engineering operation benefit and reducing its flood risk, but it nearly didn't influence the plan of hydraulic engineering. The study of this paper is helpful to the dynamic flood risk management of TGD, and provide reference for the

  8. No effect of 16 weeks flavor enhancement on dietary intake and nutritional status of nursing home eldery

    NARCIS (Netherlands)

    Essed, N.H.; Staveren, van W.A.; Kok, F.J.; Graaf, de C.

    2007-01-01

    There is a lack of data to support the long-term effect of flavor enhancement on food intake and nutritional status. Our aim was to determine if daily addition of 700 mg flavor and/or 300 mg monosodium glutamate (MSG) to the animal protein part of the cooked meal for 16 weeks leads to an increase in

  9. Three-week nutritional supplementation effect on long-term nutritional status of patients with mild Alzheimer disease.

    Science.gov (United States)

    de Sousa, Odete Luísa Vicente; Amaral, Teresa F

    2012-01-01

    Short-term nutritional supplements enable an improvement in Alzheimer patients' nutritional status, but it remains to be seen whether they will be sufficient to improve long-term nutritional status. The aim of this study was to evaluate the long-term impact of a 3-week nutritional supplementation on the nutritional status of undernourished patients with probable mild Alzheimer disease. A 21-day prospective randomized nonblinded controlled trial was conducted. Patients were followed-up for an additional period until the 90th day after the beginning of the intervention. Intervention resulted in significant improvements in Mini Nutritional Assessment (MNA) score [Mean=1.4, standard deviation (SD)=0.8 vs. 0.0 (0.1) in the control group, PAlzheimer disease (AD) patients' nutritional status. Further improvements in the AD patients' MNA mean score=1.4 (SD=2.3) versus -0.5 (SD=0.6) in the control group (P=0.003) were seen at 90 days follow-up. Data show that a 3-week nutritional supplementation has a positive long-term impact on the nutritional status of undernourished patients with mild probable AD.

  10. Doula care, early breastfeeding outcomes, and breastfeeding status at 6 weeks postpartum among low-income primiparae.

    Science.gov (United States)

    Nommsen-Rivers, Laurie A; Mastergeorge, Ann M; Hansen, Robin L; Cullum, Arlene S; Dewey, Kathryn G

    2009-01-01

    To examine associations between doula care, early breastfeeding outcomes, and breastfeeding duration. Prospective cohort. Regional hospital in northern California. Low-income, full gestation primiparae receiving doula care (n=44) or standard care (n=97). Birth outcomes and newborn feeding data obtained from the hospital record. Follow-up interviews conducted at day 3 to record the timing of onset of lactogenesis and breastfeeding behavior and at 6 weeks to obtain current breastfeeding status. Adjusting for baseline differences, women receiving doula care were significantly more likely to have a short stage II labor, a noninstrumental vaginal delivery, and to experience onset of lactogenesis within 72 hours postpartum (timely onset of lactogenesis). Overall, 68% of women receiving doula care and 54% of women receiving standard care were breastfeeding at 6 weeks. In the subset with a prenatal stressor (n=63), the doula care group was more than twice as likely to be breastfeeding at 6 weeks (89% vs. standard care, 40%). Breastfeeding at 6 weeks was also significantly associated with timely onset of lactogenesis and maternal report that the infant "sucked well" at day 3. Doula care was associated with improved childbirth outcomes and timely onset of lactogenesis. Both directly and as mediated by timely onset of lactogenesis, doula care was also associated with higher breastfeeding prevalence at 6 weeks.

  11. Ankle sprain as a work-related accident: status of proprioception after 2 weeks

    Directory of Open Access Journals (Sweden)

    Salvador González-Iñigo

    2017-12-01

    Full Text Available Purpose This study aims at verifying whether proprioception is abnormal or not, two weeks after a grade 1 and 2 ankle sprain in the scope of work-related accident. Methods A descriptive, observation and transversal study was designed to compare speed, movement and oscilation of centre of pressure in employees of companies signed up to a mutual company. Participants’ healthy feet comprised the control group, and feet that had undergone an ankle sprain due to a work-related accident comprised the cases group. The following stability tests were undertaken to both the healthy and injuried feet using a force plate: Monopodal Romberg test with eyes open, Monopodal Romberg test with eyes open on a 30 mm thick foam rubber, Monopodal Romberg test with eyes closed, and Romberg test as monopodal support with eyes closed on a 30 mm thick foam rubber. A multiple logistic regression analysis was performed. From the results of this regression model the COR curve test was performed. Results 71.7% accuracy in the predictions was attained. The equation was as follows: Condition (injured or healthy = 0.052⋅% RGC AP Movement − 0.81⋅MREO AP Movement. The variable MREO antero-posterior movement was used in the COR curve methodology. The area under the curve was greater than 0.65 and at a 95% confidence interval the 0.75 value was included, which in our case was the injured subject condition. Values for sensitivity, specificity, positive predictive value and negative predictive value were 0.667, 0.633, 64.5%, and 65.5%, respectively. Conclusion The participants in this study showed a diminished capacity for postural control in an ankle two weeks after an ankle sprain.

  12. Intervenção fonoaudiologica baseada na perspectiva comportamental em transtorno global do desenvolvimento (tgd: relato de caso

    Directory of Open Access Journals (Sweden)

    Ana Paola Nicolielo

    2014-08-01

    Full Text Available O objetivo deste trabalho foi descrever um processo de intervenção fonoaudiológica focado na adequação das habilidades linguísticas, sociais e cognitivas de uma criança com Distúrbio de Linguagem como parte de um Transtorno Global do Desenvolvimento (TGD, sob a perspectiva comportamental. A criança em questão era do gênero feminino e foi diagnosticada numa clínica-escola de Fonoaudiologia e encaminhada ao diagnóstico neurológico aos 2 anos de idade. Logo após o diagnóstico iniciou-se a intervenção fonoaudiológica individual, com base numa perspectiva comportamentalista de base mais tradicional; no entanto, ao longo do processo, houve mudanças no direcionamento da intervenção, sendo aqui relatados os dois primeiros anos de intervenção e apresentados dados da reavaliação fonoaudiológica no início do terceiro ano de intervenção. Como resultado da intervenção, houve melhora da linguagem receptiva e expressiva, sendo que a criança apresentou evolução quanto ao aspecto comportamental e aquisição de habilidades comunicativas, associando respostas verbais à ações. Além disso, houve aumento do contato ocular e do tempo de atenção e de aspectos relacionados ao simbolismo. O caso foi descrito com a preocupação de deixar claro que nem sempre é fácil a identificação da melhor abordagem terapêutica para essas crianças logo no início do processo, sendo que as decisões acerca da abordagem adequada devem ser repensadas constantemente não somente em decorrência do diagnóstico em si, mas também das manifestações da sintomatologia geral e específica – que variam conforme o desenvolvimento da criança e a evolução do processo de intervenção. Essas decisões devem ser pautadas na experiência do profissional, mas também na expectativa e no limite de cada família.

  13. Three Weeks of Anti-orthostatic Suspension had no Effect on Immune Status in a Specific-Pathogen-Free Enfvironment

    Science.gov (United States)

    Jang, Tae Young; Chang, Geun Uck; Kim, Kyu-Sung; Heo, Min-Jeong; Jung, Ah-Yeoun; Kim, Young Hyo

    2015-09-01

    Anti-Orthostatic Suspension (AOS) is a well-known murine ground-based model of simulated microgravity. However, because no commercial equipment is available for AOS in Specific-Pathogen-Free (SPF) laboratories no previous study has been conducted to examine the effect of AOS on allergic immunity. Accordingly, we developed an AOS cage suitable for SPF conditions, and evaluate its reliability and the effect of 3 weeks of AOS on immunity in a mouse model. An AOS cage were developed using stainless steel components. Fourteen female BALB/c mice were allocated to Group A (control group, n=7) or Group B (AOS, n=7). Body weights and thickness of posterior thigh muscles were measured before and after 3 weeks of AOS, and serum IgE and the titers of cytokines (IL-4, IL-5, IL-10, IL-13, and IFN- γ) in bronchoalveolar lavage (BAL) fluid were compared, as were lung histologic findings. The SPF condition was successfully maintained. No significant difference in weight gain was observed between groups A (0.9 ±1.0 g) and B (0.8 ±1.1 g, P>0.05) after the 3-week experimental period. The mean thickness of posterior thigh muscles in Group B was significantly lower than in Group A (0.7 ±0.2 versus -0.4 ±0.3 mm, P =0.001). However, group serum IgE titers, and IL-4, IL-5, IL-10, IL-13, and IFN- γ titers in BAL fluid were non-significantly different. No intergroup difference was found by histopathologic examinations of lungs. In conclusion, using AOS equipment in a SPF laboratory, immune status was not found to be significantly affected by 3 weeks AOS in healthy mice.

  14. Glucose tolerance status of Asian Indian women with gestational diabetes at 6weeks to 1year postpartum (WINGS-7).

    Science.gov (United States)

    Bhavadharini, Balaji; Anjana, Ranjit Mohan; Mahalakshmi, Manni Mohanraj; Maheswari, Kumar; Kayal, Arivudainambi; Unnikrishnan, Ranjit; Ranjani, Harish; Ninov, Lyudmil; Pastakia, Sonak D; Usha, Sriram; Malanda, Belma; Belton, Anne; Uma, Ram; Mohan, Viswanathan

    2016-07-01

    To determine postpartum glucose tolerance status among women with gestational diabetes mellitus (GDM) recruited under the Women In India with GDM Strategy (WINGS) Model of Care (MOC). Through the WINGS MOC programme, 212 women with GDM were followed till delivery between November 2013 and August 2015. All women were advised to return for a postpartum oral glucose tolerance test (OGTT) 6-12weeks after delivery. A multivariate logistic regression (MLR) model was developed to identify the risk factors for postpartum dysglycemia which was defined as presence of diabetes (DM) or prediabetes. 203/212(95.8%) women completed their postpartum OGTT. Of the 161 women (79.3%) who came back for the test between 6 and 12weeks, 2(1.2%) developed DM, 5(3.1%), isolated IFG, 13(8.1%), isolated IGT and 5(3.1%) combined IFG/IGT [dysglycemia 25(15.5%)]. 136 women (84.5%) reverted to normal glucose tolerance (NGT). Of the 42 women who came back between 12weeks and a year, 5(11.9%) developed DM, 10(23.8%), isolated IFG and 1(2.4%) combined IFG/IGT [dysglycemia 16(38.1%)]. 26/42 women (61.9%) reverted to NGT. Thus overall dysglycemia occurred in 41/203 women (20.2%). MLR showed that BMI ⩾25kg/m(2) was significantly associated with postpartum dysglycemia (odds ratio: 4.47; 95% confidence interval: 1.8-11.2, p=0.001). Among Asian Indian women with GDM, over 20% develop dysglycemia within one year postpartum, and BMI ⩾25kg/m(2) increased this risk four-fold. Early postpartum screening can identify high risk women and help plan strategies for prevention of type 2 diabetes in the future. Copyright © 2016 The Author(s). Published by Elsevier Ireland Ltd.. All rights reserved.

  15. Effect of 12-Week Vitamin D Supplementation on 25[OH]D Status and Performance in Athletes with a Spinal Cord Injury.

    Science.gov (United States)

    Flueck, Joelle Leonie; Schlaepfer, Max Walter; Perret, Claudio

    2016-09-22

    (1) BACKGROUND: studies with able-bodied athletes showed that performance might possibly be influenced by vitamin D status. Vitamin D seems to have a direct impact on neuromuscular function by docking on vitamin D receptors in the muscle tissue. Additionally, a high prevalence of vitamin D deficiency was shown not only in infants and in the elderly but also in healthy adults and spinal cord injured individuals. Therefore, the aim of our study was to investigate whether a vitamin D dose of 6000 IU daily over 12 weeks would be sufficient to increase vitamin D status in indoor wheelchair athletes to a normal or optimal vitamin D level and whether vitamin D deficiency is associated with an impairment in muscle performance in these individuals; (2) METHODS: vitamin D status was assessed in indoor elite wheelchair athletes in order to have a baseline measurement. If vitamin D status was below 75 nmol/L, athletes were supplemented with 6000 IU of vitamin D daily over 12 weeks. A vitamin D status over 75 nmol/L was supplemented with a placebo supplement. Vitamin D status, as well as a Wingate test and an isokinetic dynamometer test, were performed at baseline and after six and 12 weeks; (3) RESULTS: 20 indoor elite wheelchair athletes participated in this double-blind study. All of these athletes showed an insufficient vitamin D status at baseline and were, therefore, supplemented with vitamin D. All athletes increased vitamin D status significantly over 12 weeks and reached an optimal level. Wingate performance was not significantly increased. Isokinetic dynamometer strength was significantly increased but only in the non-dominant arm in isometric and concentric elbow flexion; (4) CONCLUSION: a dose of 6000 IU of vitamin D daily over a duration of 12 weeks seems to be sufficient to increase vitamin D status to an optimal level in indoor wheelchair athletes. It remains unclear, whether upper body performance or muscle strength and vitamin D status are associated with each

  16. Effect of 12-Week Vitamin D Supplementation on 25[OH]D Status and Performance in Athletes with a Spinal Cord Injury

    Directory of Open Access Journals (Sweden)

    Joelle Leonie Flueck

    2016-09-01

    Full Text Available (1 Background: studies with able-bodied athletes showed that performance might possibly be influenced by vitamin D status. Vitamin D seems to have a direct impact on neuromuscular function by docking on vitamin D receptors in the muscle tissue. Additionally, a high prevalence of vitamin D deficiency was shown not only in infants and in the elderly but also in healthy adults and spinal cord injured individuals. Therefore, the aim of our study was to investigate whether a vitamin D dose of 6000 IU daily over 12 weeks would be sufficient to increase vitamin D status in indoor wheelchair athletes to a normal or optimal vitamin D level and whether vitamin D deficiency is associated with an impairment in muscle performance in these individuals; (2 Methods: vitamin D status was assessed in indoor elite wheelchair athletes in order to have a baseline measurement. If vitamin D status was below 75 nmol/L, athletes were supplemented with 6000 IU of vitamin D daily over 12 weeks. A vitamin D status over 75 nmol/L was supplemented with a placebo supplement. Vitamin D status, as well as a Wingate test and an isokinetic dynamometer test, were performed at baseline and after six and 12 weeks; (3 Results: 20 indoor elite wheelchair athletes participated in this double-blind study. All of these athletes showed an insufficient vitamin D status at baseline and were, therefore, supplemented with vitamin D. All athletes increased vitamin D status significantly over 12 weeks and reached an optimal level. Wingate performance was not significantly increased. Isokinetic dynamometer strength was significantly increased but only in the non-dominant arm in isometric and concentric elbow flexion; (4 Conclusion: a dose of 6000 IU of vitamin D daily over a duration of 12 weeks seems to be sufficient to increase vitamin D status to an optimal level in indoor wheelchair athletes. It remains unclear, whether upper body performance or muscle strength and vitamin D status are

  17. Effect of a 12-week yoga therapy program on mental health status in elderly women inmates of a hospice

    Directory of Open Access Journals (Sweden)

    Meena Ramanathan

    2017-01-01

    Conclusion: It is recommended that yoga should be a part of health-care facilities for elderly as it can enhance the quality of life by improving their overall mental health status. It could provide a healthy and positive alternative from depressing negative thoughts, and give them a sense of purpose and hope.

  18. Effects of 6-week Nordic walking training on body composition and antioxidant status for women > 55 years of age

    Directory of Open Access Journals (Sweden)

    Agata Cebula

    2017-06-01

    Full Text Available Objectives: This study examined the effects of 6-week Nordic walking (NW workout with individually customized intensity, on the body composition, and oxidative stress biomarkers for women > 55 years of age. Material and Methods: Sixteen sedentary women (age 58.1±2.02 years old, body mass index (BMI 26.74±2.72 kg/m2 worked out the NW 3 times/week over the 6-week period. Training intensity, which reflected the dominance of oxygen metabolism, was determined based on changes in physiological indicators during graded exercise on a treadmill (walking with poles. The body composition and oxidative stress biomarkers in blood were measured before and after the exercise routine. Results: After the training period, body weight, body fat percentage, body mass index and uric acid levels in serum decreased significantly (p 0.05. Conclusions: Within a relatively short time, the Nordic walking with the customized intensity level focused on the dominance of fat metabolism, decreased body fat and improved the blood antioxidant defense system for previously sedentary women. Int J Occup Med Environ Health 2017;30(3:445–454

  19. Effectiveness of two weeks of high-intensity interval training on performance and hormone status in adolescent triathletes.

    Science.gov (United States)

    Lee, Chia-Lun; Hsu, Mei-Chich; Astorino, Todd A; Liu, Ta-Wei; Chang, Wen-Dien

    2017-04-01

    Weekly training volumes for triathlete are typically higher and may cause fatigue and musculoskeletal injury risk. High-intensity interval training (HIT) is a potent time-efficient strategy to induce adaptations normally associated with traditional endurance training. Therefore, the aim of this study was to investigate the effect of two weeks of in-season HIT on exercise capacity and hormonal responses in young triathletes. Twelve adolescent triathletes performed 18 sessions of HIT over 2 weeks including swim, cycle, and run events. The 6-day training blocks were separated by 1 day of recovery. Pre- and post-training, peak oxygen uptake (VO2peak) and exercise performance were assessed, and blood samples were obtained to detect changes in hormone and metabolite levels. VO2peak was significantly higher (P=0.02) post-training (56.4±8.1 mL·min-1·kg-1) versus pre-training (55.1±7.5 mL·min-1·kg-1). Mean power and total work during 6×10 s repeated-sprint tests significantly increased (P=0.03) after HIT. Additionally, 750 m swim time (pre- vs. post: 689.7±102.5 s vs. 662.0±75 s, P=0.01) and 20 km cycling time (pre- vs. post: 1856.6±274.8 s vs. 1705.4±266.8 s, P=0.02) were significantly lower post-training compared to pre-training, but there was no significant difference in 5 km run time after HIT (pre- vs. post: 1315.8±81.3 s vs. 1292.0±112.9 s, P=0.31). In contrast to pre-training, ammonia concentration was significantly increased (Ptraining. These findings suggest that two weeks of HIT using HRpeak as a monitor of physiological intensity improved VO2peak, sprint performance, and triathlon-specific performance in adolescent triathletes and attenuated levels of muscle damage.

  20. Six weeks of aerobic dance exercise improves blood oxidative stress status and increases interleukin-2 in previously sedentary women.

    Science.gov (United States)

    Leelarungrayub, Donrawee; Saidee, Kunteera; Pothongsunun, Prapas; Pratanaphon, Sainetee; YanKai, Araya; Bloomer, Richard J

    2011-07-01

    This study evaluated the change in blood oxidative stress, blood interleukin-2, and physical performance following 6 weeks of moderate intensity and duration aerobic dance exercise in 24 sedentary women. Blood samples were collected at rest twice before (baseline) and after the 6-week intervention for analysis of protein hydroperoxide (PrOOH), malondialdehyde (MDA), total anti-oxidant capacity (TAC), and interleukin-2 (IL-2) levels. Maximal treadmill run time (Time(max)) and maximal oxygen consumption (VO(2max)) were also measured. All variables were statistically analyzed with a repeated measurement ANOVA and Tukey post hoc. No differences were noted in any variable during the baseline period (p > 0.05). After aerobic dance exercise, VO(2max), Time(max), TAC and IL-2 were significantly increased, whereas MDA levels were decreased significantly (p dance exercise at a moderate intensity and duration can improve physical fitness, decrease MDA, and increase TAC and IL-2 in previously sedentary women. Copyright © 2010 Elsevier Ltd. All rights reserved.

  1. The effect of 6 weeks of Tai chi training on cognitive status, dynamic balance and quality of life in women with stroke

    Directory of Open Access Journals (Sweden)

    Manijeh Norouzian

    2017-03-01

    Full Text Available Background and Objectives: Stroke can lead to permanent disabilities, including motor and cognitive impairments. The aim of this study was to determine the effect of Tai Chi training on cognitive status, dynamic balance, and quality of life in women with stroke. Methods: In this quasi-experimental study, 20 women with stroke (mean age, 65.8±3.5 years; weight, 68.4±14kg; and body mass index, 26.3±5.1kg/m2 in Qom city, were selected voluntarily and randomly divided into experimental (N=10 and control (N=10 groups. Cognitive status, dynamic balance, and quality of life were assessed by Mini-Mental State Examination (MMSE and SF-36 quality of life questionnaires and Timed Up and Go test. Tai Chi group trained for 6 weeks, three 60-minute sessions per week (a 10-minute warm-up period, a 40-minute simplified Tai Chi exercise, and a 10-minute cool-down period. Data were analyzed using dependent and independent t-tests and (p0.05. Conclusion: According to de results of the study, it can be said that Tai Chi training as a low-intensity and simple training improves dynamic balance and quality of life in women with stroke.

  2. Comparison of the Effect of 8 weeks Aerobic and Yoga Training on Ambulatory Function, Fatigue and Mood Status in MS Patients.

    Science.gov (United States)

    Ahmadi, Azra; Arastoo, Ali Asghar; Nikbakht, Masoud; Zahednejad, Shahla; Rajabpour, Mojtaba

    2013-06-01

    Multiple Sclerosis (MS) is a disease of the central nervous system that results in many symptoms including mobility limitation and fatigue. Thirty-one MS patients, all female with mean of age of 36.75 years and Expanded Disability Status Scale scores (EDSS) of 1.0 to 4.0 were recruited. Subjects were randomly assigned to one of the three groups: treadmill training, yoga or control groups. Treadmill training and yoga practice consisted of 8 weeks (24 sessions, thrice weekly). The control group followed their own routine treatment program. Balance, speed and endurance of walking, fatigue, depression and anxiety were measured by Berg Balance scores, time for 10m walk and distance for a two minute walk, Fatigue Severity Scale (FFS), Beck Depression Inventory (BDI) and Beck Anxiety Inventory (BAI), respectively. Comparison of results have shown that pre- and post-interventions produced significant improvements in the balance score, walking endurance, FFS score, BDI score and BAI score in the treadmill training group and yoga group. However, 10m walk time decreased in the treadmill training group but did not show any clear change in the yoga group. Moreover, the analysis showed significant differences between the treadmill training group and yoga group for BAI score. These results suggest that treadmill training and yoga practice improved ambulatory function, fatigue and mood status in the individuals with mild to moderate MS.

  3. The effects of 10-week core stability training on balance in women with Multiple Sclerosis according to Expanded Disability Status Scale: a single-blinded randomized controlled trial.

    Science.gov (United States)

    Amiri, Banafsheh; Sahebozamani, Mansour; Sedighi, Behnaz

    2018-01-02

    The effect of 10-week core stability training (CST) program on balance in women with relapsing-remitting Multiple Sclerosis (MS) according to Expanded Disability Status Scale (EDSS) score. Sixty-nine MS women were randomly assigned into two groups as the intervention group and the control group. These groups were categorized into three subgroups according to the EDSS as follows: subgroup A (EDSS 2.5 to 3.5), subgroup B (EDSS 3.5 to 4.5), and subgroup C (EDSS 4.5 to 5.5). The intervention group performed a CST program for 10 weeks and to evaluate static and dynamic balance performance in pre-and post-tests, the Biodex Stability System (BSS) have been used. In addition, the participants' core muscle function was evaluated using the endurance and isometric muscle strength tests. The results show a significant difference between post-test variables of the core muscles function, static and dynamic balances in interventional subgroups in comparison with the control subgroups. The improved balance order has been given as subgroup C > B > A. The CST program could be suggested as an efficient clinical intervention for improving dynamic and static balance in the MS women due to the improvement of core muscle function, especially for the EDSS score more than 3.5. ⋅ The CST could be performed as an efficient clinical intervention for improving dynamic and static balance in MS women due to the improvement of core muscle function. ⋅ The present protocol could be helpful for the patients with MS especially for the EDSS score more than 3.5.

  4. The Effect of Eight Weeks of Tai-Chi Exercises on Status Parameters of Kyphosis and Balance among Educable Mentally Retarded Children

    Directory of Open Access Journals (Sweden)

    Tayebeh Heidari

    2016-07-01

    Full Text Available One of the most fragile stratums of every society is the people with certain disabilities, especially educable mentally retarded children. Some of the most tangible difficulties of these people are seen in their perceptual and motional abilities (coordination, balance, atmospheric awareness, time awareness, physical awareness and sense of direction. Overcoming these inabilities requires the integration of environmental information and decision making for performance of a special function. The objective of the present research is to investigate the effects of eight weeks of Tai-Chi exercises on status parameters of Kyphosis and balance among educable mentally retarded children. The research sample is consisted of 30 educable mentally retarded children suffering from Kyphosis abnormality. The sample individuals were selected from welfare centers of Tehran. After selection of samples, prior and post to execution of the protocol, the individuals were measured in terms of Kyphosis angle, chest expansion, coefficient of Delmas, spine extension and static and dynamic balances respectively through flexible rulers, tape measure, stoke test and Y test. The educable mentally retarded children were assigned to two 15 individual groups of experimental (age average of 11.6 years; average height of 142.30; average weight of 39.26kg and control (age average of 11.06; height average of 139.83 and weight average of 35.86kg. The subjects of the experimental group were participated in an 8 week course of Tai-Chi exercises in three weekly 45 minute sessions. These exercises included a 10 minute warm-up, 30 minutes of Tai-Chi movements and 5 minutes of cool-down. During this time, the subjects of the control group were not incorporated into any exercise. By the use of the Shapiro-Wilk test, the normality of data distribution was investigated and approved. Also the Leon test was used for investigation of equality of the variances. Afterwards, descriptive statistics

  5. Estado nutricional de nutrizes adolescentes em diferentes semanas pós-parto Nutritional status of lactanting adolescents in different postpartum weeks

    Directory of Open Access Journals (Sweden)

    Vilma Blondet de Azeredo

    2011-04-01

    Full Text Available OBJETIVO: avaliar as modificações do estado nutricional de nutrizes adolescentes em diferentes momentos no pós-parto. MÉTODO: estudo do tipo analítico observacional longitudinal, com acompanhamento de 50 nutrizes adolescentes da 5ª a 15ª semana pós-parto (SPP. O estado nutricional foi avaliado na 5ª, 10ª e 15ª SPP, com uso do Índice de Massa Corporal (IMC/idade. Foi utilizado o método colorimétrico para avaliação da hemoglobina e microcentrifugação para o hematócrito. Usou-se ANOVA com medidas de repetição e Tukey como pós-teste, para comparação das médias. Trabalhou-se com nível de significância de 5%. RESULTADOS: observou-se modificação no estado nutricional do período pré-gestacional para a 15ª SPP, com diminuição na frequência de voluntárias com baixo peso (de 21% para 9% e aumento nos casos de sobrepeso (de 21% para 27% e eutrofia (58% para 64%. Apesar de, em média, as concentrações de hemoglobina (12,3±1,7g/dL e hematócrito (39,0±4,0% apresentarem-se adequados, observou-se grande frequência de anemia (30% durante todo o período estudado. CONCLUSÃO: os resultados mostram incremento no peso corporal em função do tempo de lactação, aumentando o problema da obesidade na adolescência. Também foi apontado que a anemia é um problema nutricional, não apenas durante a gestação, mas também na lactação em adolescentes. Portanto, deve-se prevenir e tratar possíveis deficiências nutricionais subclínicas existentes neste momento biológico.PURPOSE: to evaluate changes in the nutritional status of lactating adolescents in different postpartum weeks. METHOD: this is an analytical, observational, longitudinal study. Lactating adolescents were followed-up from the 5th to the 15th postpartum week (PPW. The nutritional status was evaluated in the 5th, 10th and 15th PPW by the Body Mass Index (BMI/age. A colorimetric method was used to determine hemoglobin level and microcentrifugation to define

  6. Urban women's socioeconomic status, health service needs and utilization in the four weeks after postpartum hospital discharge: findings of a Canadian cross-sectional survey

    Directory of Open Access Journals (Sweden)

    Ciliska Donna

    2008-10-01

    Full Text Available Abstract Background Postpartum women who experience socioeconomic disadvantage are at higher risk for poor health outcomes than more advantaged postpartum women, and may benefit from access to community based postpartum health services. This study examined socioeconomically disadvantaged (SED postpartum women's health, and health service needs and utilization patterns in the first four weeks post hospital discharge, and compared them to more socioeconomically advantaged (SEA postpartum women's health, health service needs and utilization patterns. Methods Data collected as part of a large Ontario cross-sectional mother-infant survey were analyzed. Women (N = 1000 who had uncomplicated vaginal births of single 'at-term' infants at four hospitals in two large southern Ontario, Canada cities were stratified into SED and SEA groups based on income, social support and a universally administered hospital postpartum risk screen. Participants completed a self-administered questionnaire before hospital discharge and a telephone interview four weeks after discharge. Main outcome measures were self-reported health status, symptoms of postpartum depression, postpartum service needs and health service use. Results When compared to the SEA women, the SED women were more likely to be discharged from hospital within the first 24 hours after giving birth [OR 1.49, 95% CI (1.01–2.18], less likely to report very good or excellent health [OR 0.48, 95% CI (0.35–0.67], and had higher rates of symptoms of postpartum depression [OR 2.7, 95% CI(1.64–4.4]. No differences were found between groups in relation to self reported need for and ability to access services for physical and mental health needs, or in use of physicians, walk-in clinics and emergency departments. The SED group were more likely to accept public health nurse home visits [OR 2.24, 95% CI(1.47–3.40]. Conclusion Although SED women experienced poorer mental and overall health they reported similar

  7. Urban women's socioeconomic status, health service needs and utilization in the four weeks after postpartum hospital discharge: findings of a Canadian cross-sectional survey.

    Science.gov (United States)

    Kurtz Landy, Christine; Sword, Wendy; Ciliska, Donna

    2008-10-03

    Postpartum women who experience socioeconomic disadvantage are at higher risk for poor health outcomes than more advantaged postpartum women, and may benefit from access to community based postpartum health services. This study examined socioeconomically disadvantaged (SED) postpartum women's health, and health service needs and utilization patterns in the first four weeks post hospital discharge, and compared them to more socioeconomically advantaged (SEA) postpartum women's health, health service needs and utilization patterns. Data collected as part of a large Ontario cross-sectional mother-infant survey were analyzed. Women (N = 1000) who had uncomplicated vaginal births of single 'at-term' infants at four hospitals in two large southern Ontario, Canada cities were stratified into SED and SEA groups based on income, social support and a universally administered hospital postpartum risk screen. Participants completed a self-administered questionnaire before hospital discharge and a telephone interview four weeks after discharge. Main outcome measures were self-reported health status, symptoms of postpartum depression, postpartum service needs and health service use. When compared to the SEA women, the SED women were more likely to be discharged from hospital within the first 24 hours after giving birth [OR 1.49, 95% CI (1.01-2.18)], less likely to report very good or excellent health [OR 0.48, 95% CI (0.35-0.67)], and had higher rates of symptoms of postpartum depression [OR 2.7, 95% CI(1.64-4.4)]. No differences were found between groups in relation to self reported need for and ability to access services for physical and mental health needs, or in use of physicians, walk-in clinics and emergency departments. The SED group were more likely to accept public health nurse home visits [OR 2.24, 95% CI(1.47-3.40)]. Although SED women experienced poorer mental and overall health they reported similar health service needs and utilization patterns to more SEA women

  8. Effects of school meals with weekly fish servings on vitamin D status in Danish children: secondary outcomes from the OPUS (Optimal well-being, development and health for Danish children through a healthy New Nordic Diet) School Meal Study

    DEFF Research Database (Denmark)

    Petersen, Rikke A.; Damsgaard, Camilla T; Dalskov, Stine-Mathilde

    2015-01-01

    Children's vitamin D intake and status can be optimised to meet recommendations. We investigated if nutritionally balanced school meals with weekly fish servings affected serum 25-hydroxyvitamin D (25(OH)D) and markers related to bone in 8- to 11-year-old Danish children. We conducted an explorat......Children's vitamin D intake and status can be optimised to meet recommendations. We investigated if nutritionally balanced school meals with weekly fish servings affected serum 25-hydroxyvitamin D (25(OH)D) and markers related to bone in 8- to 11-year-old Danish children. We conducted...

  9. My week.

    Science.gov (United States)

    Russell, Helen

    2017-05-20

    May is VN Awareness Month, which aims to highlight the valuable work VNs do in practice. Here, Helen Russell, a registered veterinary nurse and co-joint venture partner (JVP) of Vets4Pets Byfleet, describes what she did over the course of one week recently. British Veterinary Association.

  10. The effect of weekly iron and vitamin A supplementation on hemoglobin levels and iron status in adolescent schoolgirls in western Kenya

    NARCIS (Netherlands)

    Leenstra, T.; Kariuki, S. K.; Kurtis, J. D.; Oloo, A. J.; Kager, P. A.; ter Kuile, F. O.

    2009-01-01

    Background/Objectives:Iron deficiency anemia is a major public health problem in developing countries and may affect school performance and physical work capacity in nonpregnant adolescents, and may increase the risk of anemia during subsequent teenage pregnancies. We assessed the effect of weekly

  11. Differential effects of baseline drinking status : Effects of an alcohol prevention program targeting students and/or parents (PAS) among weekly drinking students

    NARCIS (Netherlands)

    Koning, Ina M.; Lugtig, Peter; Vollebergh, Wilma A M

    2014-01-01

    The effects of an intervention designed to prevent onset of weekly drinking in non drinking students (PAS) were investigated in the group of students that was already drinking at baseline. A cluster randomized trial was used including 3,490 Dutch early adolescents (M age. =. 12.66, SD=. 0.49)

  12. Predictive validity of weekly monitoring of wound status using DESIGN-R score change for pressure ulcer healing: a multicenter prospective cohort study.

    Science.gov (United States)

    Iizaka, Shinji; Sanada, Hiromi; Matsui, Yuko; Furue, Masutaka; Tachibana, Takao; Nakayama, Takeo; Sugama, Junko; Furuta, Katsunori; Tachi, Masahiro; Tokunaga, Keiko; Miyachi, Yoshiki

    2012-01-01

    There are few studies on predictive validity of methods to monitor the healing process of pressure ulcers. We evaluated whether the change of DESIGN-R (rating) score could predict subsequent healing, and determined the optimal cutoff points. In a multicenter prospective cohort study, patients were followed until wound healing or censoring. Wound severity was evaluated by the DESIGN-R tool every week, and the score change was calculated over 1-4 weeks (n = 411, 286, 224, and 170, respectively). In the multivariate analyses stratified by depth, a one-point improvement in DESIGN-R score over any period was positively associated with healing within the next 30 days independent of initial wound severity (hazard ratios over each 1-4 weeks ranging from 1.16 to 1.33 for superficial ulcers and from 1.21 to 1.27 for deep ulcers; all p DESIGN-R score change below the cutoff points than that aforementioned for both depths. Weekly monitoring by the DESIGN-R tool will be advantageous for evaluating prognosis of pressure ulcers independent of initial wound severity and depth. © 2012 by the Wound Healing Society.

  13. The effect of gold kiwifruit consumed with an iron fortified breakfast cereal meal on iron status in women with low iron stores: A 16 week randomised controlled intervention study

    Directory of Open Access Journals (Sweden)

    Coad Jane

    2010-01-01

    Full Text Available Abstract Background Dietary treatment is often recommended as the first line of treatment for women with mild iron deficiency. Although it is well established that ascorbic acid enhances iron absorption, it is less clear whether the consumption of ascorbic acid rich foods (such as kiwifruit with meals fortified with iron improves iron status. The aim of this study is to investigate whether the consumption of ZESPRI® GOLD kiwifruit (a fruit high in ascorbic acid and carotenoids with an iron fortified breakfast cereal meal increases iron status in women with low iron stores. Methods/Design Eighty nine healthy women aged 18-44 years with low iron stores (serum ferritin (SF ≤ 25 μg/L, haemoglobin (Hb ≥ 115 g/L living in Auckland, New Zealand were randomised to receive an iron fortified breakfast cereal (16 mg iron per serve and either two ZESPRI® GOLD kiwifruit or a banana (low ascorbic acid and carotenoid content to eat at breakfast time every day for 16 weeks. Iron status (SF, Hb, C-reactive protein (CRP and soluble transferrin receptor (sTfR, ascorbic acid and carotenoid status were measured at baseline and after 16 weeks. Anthropometric measures, dietary intake, physical activity and blood loss were measured before and after the 16 week intervention. Discussion This randomised controlled intervention study will be the first study to investigate the effect of a dietary based intervention of an iron fortified breakfast cereal meal combined with an ascorbic acid and carotenoid rich fruit on improving iron status in women with low iron stores. Trial registration ACTRN12608000360314

  14. Differential effects of baseline drinking status: effects of an alcohol prevention program targeting students and/or parents (PAS) among weekly drinking students.

    Science.gov (United States)

    Koning, Ina M; Lugtig, Peter; Vollebergh, Wilma A M

    2014-04-01

    The effects of an intervention designed to prevent onset of weekly drinking in non drinking students (PAS) were investigated in the group of students that was already drinking at baseline. A cluster randomized trial was used including 3,490 Dutch early adolescents (M age = 12.66, SD = 0.49) randomized over four conditions; 1) parent intervention, 2) student intervention, 3) combined intervention and 4) control group. Outcome measures were amount and growth of weekly alcohol drinking measured 10, 22 and 34 months after baseline. The combined intervention significantly curbed the growth of drinking among both non-drinkers (the target group of the intervention) and drinkers at baseline. Overall, less strong increases of drinking over time are found among non-drinkers compared to drinkers at baseline. Thus, the combined PAS intervention is also effective in curbing adolescents' drinking behaviour in those who already were drinking at baseline. Broad implementation of the combined parent-student intervention is recommended. Copyright © 2014 Elsevier Inc. All rights reserved.

  15. Effects of a 12-week high-α-linolenic acid intervention on EPA and DHA concentrations in red blood cells and plasma oxylipin pattern in subjects with a low EPA and DHA status.

    Science.gov (United States)

    Greupner, Theresa; Kutzner, Laura; Nolte, Fabian; Strangmann, Alena; Kohrs, Heike; Hahn, Andreas; Schebb, Nils Helge; Schuchardt, Jan Philipp

    2018-03-01

    The essential omega-3 fatty acid alpha-linolenic acid (ALA, 18:3n3) can be converted into EPA and DHA. The aim of the present study was to determine the effect of a high-ALA diet on EPA and DHA levels in red blood cells (RBCs) and their oxylipins in the plasma of subjects with a low EPA and DHA status. Fatty acid concentrations [μg mL -1 ] and relative amounts [% of total fatty acids] in the RBCs of 19 healthy men (mean age 26.4 ± 4.6 years) were analyzed by means of GC-FID. Free plasma oxylipin concentrations were determined by LC-MS based targeted metabolomics. Samples were collected and analyzed at baseline (week 0) and after 1 (week 1), 3 (week 3), 6 (week 6), and 12 (week 12) weeks of high dietary ALA intake (14.0 ± 0.45 g day -1 ). ALA concentrations significantly (p oxylipins, the concentrations increased less rapidly and to a lesser extent compared to the concentrations of their precursor FA. LA-derived oxylipins remained unchanged and arachidonic acid and DHA oxylipin concentrations were not significantly changed. Our results confirm that the intake of ALA is not a sufficient source for the increase of EPA + DHA in subjects on a Western diet. Specifically, a high-ALA diet results in increased EPA and declined DHA concentrations. However, the changes effectively balance each other out so that ΣEPA + DHA in RBCs - which is an established marker for health protective effects of omega-3-PUFA - remains constant. The PUFA levels in RBCs reflect the concentration and its changes in plasma hydroxy- and dihydroxy-PUFA concentrations for ALA and EPA.

  16. Effect of low energy diet for eight weeks to adults with overweight or obesity on folate, retinol, vitamin B12, D and e status and the degree of inflammation: a post hoc analysis of a randomized intervention trial

    DEFF Research Database (Denmark)

    Geiker, Nina Rica Wium; Veller, Mette; Kjoelbaek, Louise

    2018-01-01

    ± 11 years with a mean ± SD BMI of 33 ± 4 kg/m2, completed an eight-week low energy diet (LED). Serum concentration of folate, retinol, B12, D and E and C-reactive protein and homocysteine (Hcy) were measured at baseline and at end of the LED. Results: At baseline, 8% of the participants were deficient...... increased (P whereas the concentration of retinol and vitamin E were reduced (P Conclusion: Eight-weeks LED resulted in 13% weight loss and an increase in the serum concentrations of folate, vitamin B12 and D. Baseline adiposity was inversely associated with folate......Background: Obesity is associated with vitamin insufficiency and low grade inflammation. The purpose of this study was to investigate the effect of weight loss on folate, retinol, vitamin B12, D and E status and the degree of inflammation. Methods: Out of 110, 85 individuals (75% women) aged 39...

  17. Association between maternal micronutrient status, oxidative stress, and common genetic variants in antioxidant enzymes at 15 weeks׳ gestation in nulliparous women who subsequently develop preeclampsia.

    Science.gov (United States)

    Mistry, Hiten D; Gill, Carolyn A; Kurlak, Lesia O; Seed, Paul T; Hesketh, John E; Méplan, Catherine; Schomburg, Lutz; Chappell, Lucy C; Morgan, Linda; Poston, Lucilla

    2015-01-01

    Preeclampsia is a pregnancy-specific condition affecting 2-7% of women and a leading cause of perinatal and maternal morbidity and mortality. Deficiencies of specific micronutrient antioxidant activities associated with copper, selenium, zinc, and manganese have previously been linked to preeclampsia at the time of disease. Our aims were to investigate whether maternal plasma micronutrient concentrations and related antioxidant enzyme activities are altered before preeclampsia onset and to examine the dependence on genetic variations in these antioxidant enzymes. Predisease plasma samples (15±1 weeks׳ gestation) were obtained from women enrolled in the international Screening for Pregnancy Endpoints (SCOPE) study who subsequently developed preeclampsia (n=244) and from age- and BMI-matched normotensive controls (n=472). Micronutrient concentrations were measured by inductively coupled plasma mass spectrometry; associated antioxidant enzyme activities, selenoprotein-P, ceruloplasmin concentration and activity, antioxidant capacity, and markers of oxidative stress were measured by colorimetric assays. Sixty-four tag-single-nucleotide polymorphisms (SNPs) within genes encoding the antioxidant enzymes and selenoprotein-P were genotyped using allele-specific competitive PCR. Plasma copper and ceruloplasmin concentrations were modestly but significantly elevated in women who subsequently developed preeclampsia (both Ppreeclampsia. The modest elevation in copper may contribute to oxidative stress, later in pregnancy, in those women that go on to develop preeclampsia. The lack of evidence to support the hypothesis that functional SNPs influence antioxidant enzyme activity in pregnant women argues against a role for these genes in the etiology of preeclampsia. Copyright © 2014 The Authors. Published by Elsevier Inc. All rights reserved.

  18. Effects of Feeding Milk Replacer Ad Libitum or in Restricted Amounts for the First Five Weeks of Life on the Growth, Metabolic Adaptation, and Immune Status of Newborn Calves

    Science.gov (United States)

    Schäff, Christine T.; Gruse, Jeannine; Maciej, Josefine; Mielenz, Manfred; Wirthgen, Elisa; Hoeflich, Andreas; Schmicke, Marion; Pfuhl, Ralf; Jawor, Paulina; Stefaniak, Tadeusz

    2016-01-01

    The pre-weaning period is critical for calf health and growth, and intensive milk feeding programs may assist postnatal development by improving body growth and organ maturation. The aim of the present work was to study the effects of ad libitum milk replacer (MR) feeding on the growth, metabolic adaptation, health, and immune status of newborn calves. Twenty-eight newborn Holstein and Holstein x Charolais crossbred calves were fed ad libitum (ADLIB) or in restricted amounts (6 liters per day; RES) during the first five weeks of life. The MR intake in the ADLIB treatment was gradually reduced at weeks 6 and 7, and all calves then received 6 liters of MR per day until day 60. Blood samples were collected to measure the plasma concentrations of metabolites, insulin, insulin-like growth factor (IGF)-I and IGF binding proteins (IGFBP), immunoglobulins, and acute phase proteins. The expression of mRNA associated with both the somatotropic axis and gluconeogenic enzymes was measured in the liver on day 60. Intensive feeding improved MR intake and growth in ADLIB without influencing concentrate intake. Carcass weight, perirenal fat, and muscle mass were greater in ADLIB. Plasma concentrations of glucose, triglycerides, insulin, and IGF-I were greater, whereas plasma concentrations of β-hydroxybutyrate, total protein, albumin, urea, IGFBP-2 and -4, and fibrinogen were lower at distinct time points in ADLIB. The hepatic mRNA expression of cytosolic phosphoenolpyruvate carboxykinase was greater in ADLIB. Most metabolic and endocrine differences occurred during the MR feeding period, but a slightly greater concentrate intake was associated with increased plasma IGF-I and insulin at the end of the study. The immune and health status of the calves were not affected by MR feeding. However, increased plasma fibrinogen in the RES group suggested differences in the acute phase response. PMID:28036351

  19. Physical activity in 3-6 year old children measured by SenseWear Pro®: direct accelerometry in the course of the week and relation to weight status, media consumption, and socioeconomic factors.

    Science.gov (United States)

    Vorwerg, Yvonne; Petroff, David; Kiess, Wieland; Blüher, Susann

    2013-01-01

    Data on objectively measured physical activity (PA) in preschoolers are controversial. Direct accelerometry was performed in children aged 3-6 years, and differences in PA patterns over the course of the week were evaluated. Data were analyzed with gender, BMI, lifestyle, and socioeconomic parameters as covariates. PA was measured in 119 children by the SensewearPro® accelerometer and analyzed in the 92 (40 girls) that wore it for at least 4 days including one day of the weekend. Median measuring time in this group was 7 consecutive days (median/mean daily measuring time: 23.5 h/d and 21.8 h/d, respectively), corresponding to 834,000 analyzed minutes. PA questionnaires were completed by 103 parents and 87 preschool teachers to collect anthropometric, lifestyle, and socioeconomic data. Median daily PA (MET>3) was 4.3 hours (mean: 4.4 hours). Boys spent an estimated 52 min/week more being very active (MET>6) than girls (95% CI [6, 96] min/week, p = 0.02). PA was lower during the weekend (3.7 h/d) compared to weekdays (4.5 h/d), p = 3 × 10(-6)), where a 95% CI for the difference is [0.5, 1.0] h/d. PA levels did not differ between overweight/obese children (median 4.7 h/d) and normal-weight peers (median 4.2 h/d). Daily media consumption increased with decreasing social class on weekdays (p = 0.05) and during the weekend (p = 0.01), but was not related to the amount of daily PA. A multivariate regression with BMI-SDS as independent variable and gender, age, amount of PA>6 MET, parental BMI, media time and socioeconomic status as explanatory variables revealed that only SES had a significant contribution. The negative impact of obesity-promoting factors in older children is rather low for preschoolers, but there is evidently a gradient in PA between weekdays and weekends already in this age group. Weight status of preschoolers is already considerably influenced by SES, but not physical activity levels.

  20. Physical activity in 3-6 year old children measured by SenseWear Pro®: direct accelerometry in the course of the week and relation to weight status, media consumption, and socioeconomic factors.

    Directory of Open Access Journals (Sweden)

    Yvonne Vorwerg

    Full Text Available BACKGROUND: Data on objectively measured physical activity (PA in preschoolers are controversial. Direct accelerometry was performed in children aged 3-6 years, and differences in PA patterns over the course of the week were evaluated. Data were analyzed with gender, BMI, lifestyle, and socioeconomic parameters as covariates. METHODS: PA was measured in 119 children by the SensewearPro® accelerometer and analyzed in the 92 (40 girls that wore it for at least 4 days including one day of the weekend. Median measuring time in this group was 7 consecutive days (median/mean daily measuring time: 23.5 h/d and 21.8 h/d, respectively, corresponding to 834,000 analyzed minutes. PA questionnaires were completed by 103 parents and 87 preschool teachers to collect anthropometric, lifestyle, and socioeconomic data. RESULTS: Median daily PA (MET>3 was 4.3 hours (mean: 4.4 hours. Boys spent an estimated 52 min/week more being very active (MET>6 than girls (95% CI [6, 96] min/week, p = 0.02. PA was lower during the weekend (3.7 h/d compared to weekdays (4.5 h/d, p = 3 × 10(-6, where a 95% CI for the difference is [0.5, 1.0] h/d. PA levels did not differ between overweight/obese children (median 4.7 h/d and normal-weight peers (median 4.2 h/d. Daily media consumption increased with decreasing social class on weekdays (p = 0.05 and during the weekend (p = 0.01, but was not related to the amount of daily PA. A multivariate regression with BMI-SDS as independent variable and gender, age, amount of PA>6 MET, parental BMI, media time and socioeconomic status as explanatory variables revealed that only SES had a significant contribution. CONCLUSION: The negative impact of obesity-promoting factors in older children is rather low for preschoolers, but there is evidently a gradient in PA between weekdays and weekends already in this age group. Weight status of preschoolers is already considerably influenced by SES, but not physical activity levels.

  1. The ATLAS Glasgow Overview Week

    CERN Multimedia

    Richard Hawkings

    2007-01-01

    The ATLAS Overview Weeks always provide a good opportunity to see the status and progress throughout the experiment, and the July week at Glasgow University was no exception. The setting, amidst the traditional buildings of one of the UK's oldest universities, provided a nice counterpoint to all the cutting-edge research and technology being discussed. And despite predictions to the contrary, the weather at these northern latitudes was actually a great improvement on the previous few weeks in Geneva. The meeting sessions comprehensively covered the whole ATLAS project, from the subdetector and TDAQ systems and their commissioning, through to offline computing, analysis and physics. As a long-time ATLAS member who remembers plenary meetings in 1991 with 30 people drawing detector layouts on a whiteboard, the hardware and installation sessions were particularly impressive - to see how these dreams have been translated into 7000 tons of reality (and with attendant cabling, supports and services, which certainly...

  2. Different milk feeding intensities during the first 4 weeks of rearing dairy calves: Part 2: Effects on the metabolic and endocrine status during calfhood and around the first lactation.

    Science.gov (United States)

    Kesser, J; Korst, M; Koch, C; Romberg, F-J; Rehage, J; Müller, U; Schmicke, M; Eder, K; Hammon, H M; Sadri, H; Sauerwein, H

    2017-04-01

    Feeding dairy calves at high intensity has been demonstrated to increase milk yield in later life. We investigated the effect of 3 different feeding regimens in the preweaning period on the metabolic and endocrine status during calfhood and in heifers at the onset of the first lactation. In trial 1, 57 German Holstein calves were allocated to 3 different feeding groups: milk replacer restricted to 6.78 kg/calf per day, 11.5% solids (MR-res, n = 20), milk replacer 13.8% solids, ad libitum (MR-ad lib, n = 17), and whole milk ad libitum (WM-ad lib, n = 20). All calves received ad libitum colostrum for 3 d postnatal (p.n.). From d 4 to 27, all calves were fed according to their respective feeding regimen, resulting in average intakes of 6.38, 9.25, and 9.47 kg/d in MR-res, MR-ad lib, and WM-ad lib, respectively. Thereafter, all calves were fed according to the MR-res regimen until weaning at d 55 (gradually until d 69 p.n.). Blood samples were collected on d 0 before colostrum intake and on d 1, 3, 11, 22, 34, 43, 52, 70, 90, and 108 p.n. Liver biopsies were taken on d 19 and 100, and on d 22, 52, and 108 p.n. intravenous glucose tolerance tests were performed. The male calves (n = 8 to 10 per group) underwent also an insulin tolerance test on d 24, 54, and 110 p.n. The females (n = 28) from trial 1 were further reared and bred as common practice, and were enrolled in trial 2 when beginning the last trimester of pregnancy. Blood samples were collected monthly antepartum starting 91 d before calving and weekly (0-70 d) postpartum. Trial 1 was subdivided into 4 phases (P): P0 (d 0-1), P1 (d 2-27), P2 (d 28-69), and P3 (d 70-110 p.n.). In trial 1, the leptin and adiponectin concentrations increased with colostrum intake. Differences in fatty acids, insulin, adiponectin, revised quantitative insulin sensitivity check index (RQUICKI), and variables from the glucose tolerance tests were largely limited to P1. The MR-res group had greater RQUICKI and fatty acid values, and

  3. Phun Week: Understanding Physiology

    Science.gov (United States)

    Limson, Mel; Matyas, Marsha Lakes

    2009-01-01

    Topics such as sports, exercise, health, and nutrition can make the science of physiology relevant and engaging for students. In addition, many lessons on these topics, such as those on the cardiovascular, respiratory, and digestive systems, align with national and state life science education standards. Physiology Understanding Week (PhUn…

  4. My week: Marc Armour.

    Science.gov (United States)

    2017-03-11

    Marc Armour, is a fourth-year vet student at the Royal Veterinary College. Now on rotations, he chose to spend a week doing EMS with the BVA's journals, which are published by BMJ. Here's how he got on. British Veterinary Association.

  5. Spiral 2 Week

    International Nuclear Information System (INIS)

    2007-01-01

    The main goal of this meeting is to present and discuss the current status of the Spiral-2 project at GANIL in front of a large community of scientists and engineers. Different issues have been tackled particularly the equipment around Spiral-2 like injectors, cryo-modules or beam diagnostics, a workshop was devoted to other facilities dedicated to radioactive ion beam production. This document gathers only the slides of the presentations

  6. Spiral 2 Week

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2007-07-01

    The main goal of this meeting is to present and discuss the current status of the Spiral-2 project at GANIL in front of a large community of scientists and engineers. Different issues have been tackled particularly the equipment around Spiral-2 like injectors, cryo-modules or beam diagnostics, a workshop was devoted to other facilities dedicated to radioactive ion beam production. This document gathers only the slides of the presentations.

  7. CERN safety week

    CERN Multimedia

    DG Unit

    2009-01-01

    Following an increase in the number of accidents in 2008, the Safety Commission is organising a CERN safety week from 8 to 12 June for riders of bicycles, scooters and motorbikes. We invite you to take part in the programme, which will be held in the Main Building (Bldg. 500) and will consist of an exhibition, organised events and hands-on activities, including demonstrations of emergency braking, a driving simulator, simulation of what it feels like to drive under the influence of alcohol, demonstrations by the Fire Brigade, video projections, etc. There will also be a number of prizes to be won. Please sign up via your DSO.

  8. Soft Robotics Week

    CERN Document Server

    Rossiter, Jonathan; Iida, Fumiya; Cianchetti, Matteo; Margheri, Laura

    2017-01-01

    This book offers a comprehensive, timely snapshot of current research, technologies and applications of soft robotics. The different chapters, written by international experts across multiple fields of soft robotics, cover innovative systems and technologies for soft robot legged locomotion, soft robot manipulation, underwater soft robotics, biomimetic soft robotic platforms, plant-inspired soft robots, flying soft robots, soft robotics in surgery, as well as methods for their modeling and control. Based on the results of the second edition of the Soft Robotics Week, held on April 25 – 30, 2016, in Livorno, Italy, the book reports on the major research lines and novel technologies presented and discussed during the event.

  9. ATLAS overview week highlights

    CERN Multimedia

    D. Froidevaux

    2005-01-01

    A warm and early October afternoon saw the beginning of the 2005 ATLAS overview week, which took place Rue de La Montagne Sainte-Geneviève in the heart of the Quartier Latin in Paris. All visitors had been warned many times by the ATLAS management and the organisers that the premises would be the subject of strict security clearance because of the "plan Vigipirate", which remains at some level of alert in all public buildings across France. The public building in question is now part of the Ministère de La Recherche, but used to host one of the so-called French "Grandes Ecoles", called l'Ecole Polytechnique (in France there is only one Ecole Polytechnique, whereas there are two in Switzerland) until the end of the seventies, a little while after it opened its doors also to women. In fact, the setting chosen for this ATLAS overview week by our hosts from LPNHE Paris has turned out to be ideal and the security was never an ordeal. For those seeing Paris for the first time, there we...

  10. A memorable week

    CERN Multimedia

    2012-01-01

    This has been a memorable week for CERN, starting with the award of a Special Fundamental Physics Prize and ending with the handover of the CERN Council Presidency from Michel Spiro to Agnieszka Zalewska. In between, the LHC team demonstrated its expertise with a successful pilot run with 25 nanosecond bunch spacing, a new application for Associate Membership was received, and we had good news on the budget.   The award of the Fundamental Physics Prize, and the manner in which it was divided between ATLAS, CMS and the LHC, is fitting recognition of the efforts of the thousands of people who have contributed over many years to the success of our flagship scientific endeavour. In making the award, the Milner Foundation aims to raise the profile of fundamental physics and its value to society. The Fundamental Physics Prize comes hot on the heels of the European Physical Society’s first Edison Volta Prize, which Sergio Bertolucci, Steve Myers and I were honoured to accept on behalf of t...

  11. Solar Week: Learning from Experience

    Science.gov (United States)

    Alexander, D.; Hauck, K.

    2003-12-01

    Solar Week is a week-long set of games and activities allowing students to interact directly with solar science and solar scientists. Solar Week was developed as a spin-off of the highly successful Yohkoh Public Outreach Project (YPOP). While YPOP provided access to solar images, movies and activities, the main goal of Solar Week was to enhance the participation of women, who are under-represented in the physical sciences. Solar Week achieves this by providing young women, primarily in grades 6-8, with access to role models in the sciences. The scientists participating in Solar Week are women from a variety of backgrounds and with a variety of scientific expertise. In this paper, our aim is to provide some insight into developing activity-based space science for the web and to discuss the lessons-learned from tailoring to a specific group of participants.

  12. Elective caesarean section at 38 weeks versus 39 weeks

    DEFF Research Database (Denmark)

    Glavind, Julie; Kindberg, S F; Uldbjerg, N

    2013-01-01

    To investigate whether elective caesarean section before 39 completed weeks of gestation increases the risk of adverse neonatal or maternal outcomes.......To investigate whether elective caesarean section before 39 completed weeks of gestation increases the risk of adverse neonatal or maternal outcomes....

  13. Site status monitoring report and Site Ranking Form for underground storage tank 2331-U at Building 9201-1

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-05-01

    The purpose of this document is to present potentiometric, groundwater quality and vapor monitoring data required for site status monitoring of underground storage tank (UST) 2331-U at the Building 9201-1 Site. Site status monitoring has been conducted at the site as part of a Monitoring Only program approved by the Tennessee Department of Environment and Conservation (TDEC) based on review and approval of Site Ranking (Site Ranking Form approved May 23, 1994). This document presents the results of the fourth semiannual site status monitoring that was performed in April 1996. Site status monitoring and preparation of this report have been conducted in accordance with the requirements of TDEC Rule 1200-1-15 and the TDEC UST Reference Handbook, Second Edition (TDEC 1994) Technical Guidance Document (TGD) 007. This document is organized into three sections with two Appendices. Section 1 presents introductory information relative to the site including the regulatory initiative and a site description. Section 2 includes the results of measurement and sampling of monitoring wells GW-193, GW-657, GW-707, GW-708, GW-808, GW-809, and GW-810. Section 3 presents data from vapor monitoring conducted in subsurface utilities present at the site. Appendix A contains the original analytical laboratory results for environmental and quality control samples.

  14. Astronomy Week in Madeira, Portugal

    Science.gov (United States)

    Augusto, P.; Sobrinho, J. L.

    2012-05-01

    The outreach programme Semanas da Astronomia (Astronomy Weeks) is held in late spring or summer on the island of Madeira, Portugal. This programme has been attracting enough interest to be mentioned in the regional press/TV/radio every year and is now, without doubt, the astronomical highlight of the year on Madeira. We believe that this programme is a good case study for showing how to attract the general public to astronomy in a small (population 250 000, area 900 km2) and fairly isolated place such as Madeira. Our Astronomy Weeks have been different each year and have so far included exhibitions, courses, talks, a forum, documentaries, observing sessions (some with blackouts), music and an astro party. These efforts may contribute towards putting Madeira on the map with respect to observational astronomy, and have also contributed to the planned installation of two observatories in the island.

  15. ATLAS Overview Week 2009 Barcelona

    CERN Multimedia

    Claudia Marcelloni

    2009-01-01

    From October 5th to October 9th about 400 physicists from the ATLAS Collaboration met in Barcelona (Catalonia) to discuss the status of the experiment. The event was organized by the Institut de Física d'Altes Energies (IFAE), a member of the ATLAS Collaboration. Besides the Scientific program, few social events were organized, such as Reception at the Palau de Pedralbes, a visit to the Fundacio Joan Miro and a social dinner at Maremagnunm hall.

  16. ATLAS Overview Week at Brookhaven

    CERN Multimedia

    Pilcher, J

    Over 200 ATLAS participants gathered at Brookhaven National Laboratory during the first week of June for our annual overview week. Some system communities arrived early and held meetings on Saturday and Sunday, and the detector interface group (DIG) and Technical Coordination also took advantage of the time to discuss issues of interest for all detector systems. Sunday was also marked by a workshop on the possibilities for heavy ion physics with ATLAS. Beginning on Monday, and for the rest of the week, sessions were held in common in the well equipped Berkner Hall auditorium complex. Laptop computers became the norm for presentations and a wireless network kept laptop owners well connected. Most lunches and dinners were held on the lawn outside Berkner Hall. The weather was very cooperative and it was an extremely pleasant setting. This picture shows most of the participants from a view on the roof of Berkner Hall. Technical Coordination and Integration issues started the reports on Monday and became a...

  17. Nuclear Medicine week in Colombia

    International Nuclear Information System (INIS)

    Padhy, A.K.

    2003-01-01

    During the week of 6-12 October 2003 the IAEA organized a Research Coordination Meeting on 'Relationship between lower Respiratory Tract Infection, Gastroesophageal reflux and bronchial Asthma in children' at Hospital San Ignacio in Bogota. Besides there were four workshops in Bogota; workshops on Bone infection and Bone scan in Pediatric ortopaedics at Hospital Militar and Fundacion CardioInfantil, a workshop for Nuclear Medicine Technologists and a workshop on Sentinel Lymph Node mapping and Surgical Gamma Probe Application at Institute of Oncology. A nuclear cardiology workshop was organized in Medellin, and finally crowning them all was the 9th Congress of the Colombian Association of Nuclear Medicine at Cali from 10-12 October, 2003; probably the largest and best Colombian nuclear medicine congress every held in the country. A workshop was also organized in Cali for nuclear medicine technologists in conjunction with the Annual Convention. It was a mix of IAEA's Technical Cooperation and Regular Budget activities along with the activities of Colombian Association of Nuclear Medicine, bringing in absolute synergy to galvanize the entire nuclear medicine community of the country. The week saw nuclear medicine scientists from more than 20 IAEA Member States converging on Colombia to spread the message of nuclear medicine, share knowledge and to foster International understanding and friendship among the nuclear medicine people of the world

  18. Night work, long work weeks, and risk of accidental injuries

    DEFF Research Database (Denmark)

    Larsen, Ann D.; Hannerz, Harald; Møller, Simone V.

    2017-01-01

    Objectives: The aims of this study were to (i) investigate the association between night work or long work weeks and the risk of accidental injuries and (ii) test if the association is affected by age, sex or socioeconomic status. Methods: The study population was drawn from the Danish version...... of the European Labour Force Survey from 1999-2013. The current study was based on 150 438 participants (53% men and 47% women). Data on accidental injuries were obtained at individual level from national health registers. We included all 20-59-year-old employees working ≥32 hours a week at the time...

  19. A busy week for Council

    CERN Multimedia

    2009-01-01

    This has been a busy week for the CERN Council, and there is much to report. Firstly, I’m pleased to say that Council approved the Organization’s Medium Term Plan, and with it the budget for financial year 2010. In a time of global recession, this is a strong vote of confidence from the Member States. This meeting of Council provided an opportunity for the working group on the scientific and geographical enlargement of CERN to set out a roadmap towards its final report, which is to be made at Council’s December session this year. One part of the process over the coming months is to bring the major players in particle physics from beyond the European region into the discussion, ensuring that the working group’s recommendations lead to an optimum position for CERN and European particle physics in the global context. An indicator of the continuing attractiveness of CERN is the fact that Council has received four new applications...

  20. Web Lectures - ATLAS Overview Week

    CERN Multimedia

    Tushar Bhatnagar; Jeremy Herr; Mitch McLachlan; Homer A. Neal

    2007-01-01

    ATLAS Web Archives Web Archives of the ATLAS Overview Week in Glasgow are now available from the University of Michigan portal here. Archives of ATLAS Plenary Sessions, Workshops, Meetings, and Tutorials recorded over the past two years are available via the University of Michigan Lecture Portal. Other recent additions include the ROOT Workshop held at CERN on March 26-27, the Physics Analysis Tools Workshop held in Bergen, Norway on April 23-27, and the CTEQ Workshop: "Physics at the LHC: Early Challenges" held at Michigan State University on May 14-15. Viewing requires a standard Web browser with RealPlayer plug-in (included in most browsers automatically) and works on any major platform. Lectures can be viewed directly over the Web or downloaded locally. In addition, you will find access to a variety of general tutorials and events via the portal. Feedback & Suggestions Welcome Suggestions for events or tutorials to record in 2007, as well as feedback on existing archives, is always welcome...

  1. What Is Known and Unknown About Twice-Weekly Hemodialysis.

    Science.gov (United States)

    Obi, Yoshitsugu; Eriguchi, Rieko; Ou, Shuo-Ming; Rhee, Connie M; Kalantar-Zadeh, Kamyar

    2015-01-01

    The 2006 Kidney Disease Outcomes Quality Initiative guidelines suggest twice-weekly or incremental hemodialysis for patients with substantial residual kidney function (RKF). However, in most affluent nations de novo and abrupt transition to thrice-weekly hemodialysis is routinely prescribed for all dialysis-naïve patients regardless of their RKF. We review historical developments in hemodialysis therapy initiation and revisit twice-weekly hemodialysis as an individualized, incremental treatment especially upon first transitioning to hemodialysis therapy. In the 1960's, hemodialysis treatment was first offered as a life-sustaining treatment in the form of long sessions (≥10 hours) administered every 5 to 7 days. Twice- and then thrice-weekly treatment regimens were subsequently developed to prevent uremic symptoms on a long-term basis. The thrice-weekly regimen has since become the 'standard of care' despite a lack of comparative studies. Some clinical studies have shown benefits of high hemodialysis dose by more frequent or longer treatment times mainly among patients with limited or no RKF. Conversely, in selected patients with higher levels of RKF and particularly higher urine volume, incremental or twice-weekly hemodialysis may preserve RKF and vascular access longer without compromising clinical outcomes. Proposed criteria for twice-weekly hemodialysis include urine output >500 ml/day, limited interdialytic weight gain, smaller body size relative to RKF, and favorable nutritional status, quality of life, and comorbidity profile. Incremental hemodialysis including twice-weekly regimens may be safe and cost-effective treatment regimens that provide better quality of life for incident dialysis patients who have substantial RKF. These proposed criteria may guide incremental hemodialysis frequency and warrant future randomized controlled trials. © 2015 S. Karger AG, Basel.

  2. No Child Left Inside Week: Pilot Program

    OpenAIRE

    Clark, Jamie C.

    2013-01-01

    This program evaluation assessed the feasibility and effectiveness of a free No Child Left Inside (NCLI) week-long outdoor program to coincide with the Utah state-designated No Child Left Inside Week. The pilot program was implemented at the community level in Cache Valley, Utah, in 2012. Families attended eleven activities throughout the week that included hands-on experience and participation. A community BioBlitz was also planned as a conclusion to the week. Survey results demonstrate incr...

  3. Understanding Infidelity: An Interview with Gerald Weeks

    Science.gov (United States)

    Smith, Travis

    2011-01-01

    In this interview, Gerald Weeks shares his expertise on the topic of infidelity and couples counseling. Dr. Weeks defines infidelity, presents assessment strategies for treating the issue of infidelity, and discusses an intersystemic model for infidelity treatment when counseling couples. Dr. Weeks also provides insight into common mistakes made…

  4. Effect of low energy diet for eight weeks to adults with overweight or obesity on folate, retinol, vitamin B12, D and e status and the degree of inflammation: a post hoc analysis of a randomized intervention trial

    DEFF Research Database (Denmark)

    Geiker, Nina Rica Wium; Veller, Mette; Kjoelbaek, Louise

    2018-01-01

    ± 11 years with a mean ± SD BMI of 33 ± 4 kg/m2, completed an eight-week low energy diet (LED). Serum concentration of folate, retinol, B12, D and E and C-reactive protein and homocysteine (Hcy) were measured at baseline and at end of the LED. Results: At baseline, 8% of the participants were deficient...... were positively associated with CRP (P Homocysteine was inversely associated with all vitamins but retinol (P

  5. SPIRAL2 Week 2012 - Slides of the presentations

    International Nuclear Information System (INIS)

    Staley, F.; Jacquemet, M.; Lewitowicz, M.; Bertrand, P.; Tuske, O.; Caruso, A.; Leyge, J.F.; Perrot, L.; Di Giacomo, M.; Ausset, P.; Moscatello, M.H.; Savalle, A.; Rannou, B.; Lambert, M.; Petit, E.; Hulin, X.; Barre-Boscher, N.; Tusseau-Nenez, S.; Tecchio, L.B.

    2013-01-01

    The main goal of the 5. edition of the SPIRAL2 Week is to present and discuss the current status of the SPIRAL2 project in front of a large community of scientists and engineers. The program of the meeting will include presentations on scientific and technical developments related to the baseline project, experiments and theory. The main topics to be discussed at the conference are: -) physics and detectors at SPIRAL2, -) driver accelerators, -) production of radioactive ion beams (RIB), -) safety, -) buildings and infrastructure, -) RIB facilities worldwide, and -) SPIRAL2 preparatory phase. This document is made up of the slides of the presentations

  6. 78 FR 24323 - National Park Week, 2013

    Science.gov (United States)

    2013-04-24

    ... National Park Week, 2013 By the President of the United States of America A Proclamation For generations... something to be used up, but as a treasure to be passed on. During National Park Week, we celebrate the..., the National Park Service will make that opportunity available to everyone by offering free admission...

  7. Banned Books Week: Just the Beginning

    Science.gov (United States)

    Adams, Helen R.

    2009-01-01

    Founded in 1982, Banned Books Week is celebrated annually during the last week in September and will be observed from September 26-October 3 in 2009. The event acknowledges Americans' right to read the books of their choice regardless of whether the ideas, language, or images are controversial. This annual observance of banned books is a good…

  8. 75 FR 20885 - National Park Week, 2010

    Science.gov (United States)

    2010-04-21

    ... Victims and Survivors of Terrorism, 2010 #0; #0; #0; Presidential Documents #0; #0; #0;#0;Federal Register... From the Federal Register Online via the Government Publishing Office ] Part II The President Proclamation 8498--National Park Week, 2010 Proclamation 8499--National Crime Victims' Rights Week, 2010...

  9. National Poison Prevention Week Promotional Materials.

    Science.gov (United States)

    Poison Prevention Week Council, Washington, DC.

    This collection of materials for parents, early childhood workers, the elderly, and anyone in situations requiring safeguards against poisoning, spans the years 1993 and 1994 and is intended to promote National Poison Prevention Week. The materials included are: (1) the 31-page, illustrated report on National Poison Prevention Week for 1993,…

  10. Student Time Usage during Fall Reading Week

    Science.gov (United States)

    Cramer, Ken; Pschibul, Rebecca

    2017-01-01

    The present study investigated the time usage and levels of perceived stress, academic workload, and recreation time for 177 students at the University of Windsor before, during, and after Fall Reading Week (FRW). Over a three-week span (at various times of the day), students received a message to their smartphone to complete a 20-second survey…

  11. Vehicle Technologies Fact of the Week 2015

    Energy Technology Data Exchange (ETDEWEB)

    Davis, Stacy C. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Diegel, Susan W. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Moore, Sheila A. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Boundy, Robert G. [Roltek, Inc., Clinton, TN (United States)

    2016-05-01

    Each week the U.S. Department of Energy s Vehicle Technology Office (VTO) posts a Fact of the Week on their website: http://www1.eere.energy.gov/vehiclesandfuels/ . These Facts provide statistical information, usually in the form of charts and tables, on vehicle sales, fuel economy, gasoline prices, and other transportation-related trends. Each Fact is a stand-alone page that includes a graph, text explaining the significance of the data, the supporting information on which the graph was based, and the source of the data. A link to the current week s Fact is available on the VTO homepage, but older Facts (back to 2009) are archived and still available at: http://energy.gov/eere/vehicles/current-and-past-years-facts-week. Each Fact of the Week website page includes a link to an Excel file. That file contains the data from the Supporting Information section of the page so that researchers can easily use data from the Fact of the Week in their work. Beginning in August of 2015, a subscription list is available on the DOE website so that those interested can sign up for an email to be sent each Monday which includes the text and graphic from the current week s Fact. This report is a compilation of the Facts that were posted during calendar year 2015. The Facts were created, written and prepared by staff in Oak Ridge National Laboratory's Center for Transportation Analysis.

  12. Status epilepticus

    NARCIS (Netherlands)

    Hensiek, AE; Absalom, Anthony

    2006-01-01

    Status epilepticus is defined as epileptic activity that continues for more than 30 minutes as a single seizure or as recurrent seizures without inter-ictal return of consciousness. The seizure activity is usually classified as partial or generalized. Although status epilepticus is an uncommon

  13. 77 FR 22177 - National Volunteer Week, 2012

    Science.gov (United States)

    2012-04-12

    ...--National Former Prisoner of War Recognition Day, 2012 #0; #0; #0; Presidential Documents #0; #0; #0;#0...-class education for every child to an economy built to last. During National Volunteer Week, we pay...

  14. Evaluation of an 8-week mailed healthy-weight intervention.

    Science.gov (United States)

    O'Loughlin, J; Paradis, G; Meshefedjian, G; Kishchuk, N

    1998-01-01

    This study investigated the impact of a low-intensity, healthy-weight intervention among adult volunteers in a low-income, inner-city neighborhood. The intervention, which comprised 18 pamphlets mailed to participants' homes over 8 weeks, focused on increasing awareness of healthy weight ranges, increasing self-acceptance and satisfaction with weight, and improving eating habits, while downplaying dieting and weight loss. Subjects were recruited from households randomly selected from residential telephone subscriber lists. The 188 volunteers (23.0% of 816 persons contacted) were randomly assigned to intervention or control status. Psychosocial and behavioral measures were administered by telephone 1 week before and 2 weeks after the intervention. After exposure to the pamphlets, intervention subjects were more likely than controls to know how to control their weight. They were more satisfied with their weight and less likely to report they were too heavy. They reported less high-fat/junk food consumption, more improvements in their eating habits, and more frequent exercise. This inexpensive, low-intensity intervention was effective in supporting change processes among volunteers who wanted to learn about weight control, to improve eating habits, and to improve health.

  15. Stock Status

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — These data inform the public of the most recent stock status for all stocks (FSSI and non-FSSI) in the fishery management unit contained in a fishery managment plan....

  16. Factors Influencing Amount of Weekly Exercise Time in Colorectal Cancer Survivors.

    Science.gov (United States)

    Chou, Yun-Jen; Lai, Yeur-Hur; Lin, Been-Ren; Liang, Jin-Tung; Shun, Shiow-Ching

    Performing regular exercise of at least 150 minutes weekly has benefits for colorectal cancer survivors. However, barriers inhibit these survivors from performing regular exercise. The aim of this study was to explore exercise behaviors and significant factors influencing weekly exercise time of more than 150 minutes in colorectal cancer survivors. A cross-sectional study design was used to recruit participants in Taiwan. Guided by the ecological model of health behavior, exercise barriers were assessed including intrapersonal, interpersonal, and environment-related barriers. A multiple logistic regression was used to explore the factors associated with the amount of weekly exercise. Among 321 survivors, 57.0% of them had weekly exercise times of more than 150 minutes. The results identified multiple levels of significant factors related to weekly exercise times including intrapersonal factors (occupational status, functional status, pain, interest in exercise, and beliefs about the importance of exercise) and exercise barriers related to environmental factors (lack of time and bad weather). No interpersonal factors were found to be significant. Colorectal cancer survivors experienced low levels of physical and psychological distress. Multiple levels of significant factors related to exercise time including intrapersonal factors as well as exercise barriers related to environmental factors should be considered. Healthcare providers should discuss with their patients how to perform exercise programs; the discussion should address multiple levels of the ecological model such as any pain problems, functional status, employment status, and time limitations, as well as community environment.

  17. Vehicle Technologies Fact of the Week 2013

    Energy Technology Data Exchange (ETDEWEB)

    Davis, Stacy Cagle [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Williams, Susan E. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Moore, Sheila A. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Boundy, Robert Gary [Roltek, Inc., Clinton, TN (United States)

    2014-03-01

    Each week the U.S. Department of Energy s Vehicle Technology Office (VTO) posts a Fact of the Week on their website: http://www1.eere.energy.gov/vehiclesandfuels/ . These Facts provide statistical information, usually in the form of charts and tables, on vehicle sales, fuel economy, gasoline prices, and other transportation-related trends. Each Fact is a stand-alone page that includes a graph, text explaining the significance of the data, the supporting information on which the graph was based, and the source of the data. A link to the current week s Fact is available on the VTO homepage, but older Facts are archived and still available at: http://www1.eere.energy.gov/vehiclesandfuels/facts/. This report is a compilation of the Facts that were posted during calendar year 2013. The Facts were written and prepared by staff in Oak Ridge National Laboratory's Center for Transportation Analysis.

  18. IRVINGIA GABONENSIS FOR TWENTY-FOUR WEEKS

    African Journals Online (AJOL)

    ID 12 15 18 21 24. Time (Weeks). Figure 5: Effects of I. gabonensis on mean corpuscular volume (MCV) of normal rabbits. Values carrying notations are statistically different from control at p<0.05. ©CMS UNIBEN [MBR zo12=11(2) ...

  19. Sea/River Week Career Profiles.

    Science.gov (United States)

    Alaska State Dept. of Education, Juneau. Div. of Adult and Vocational Education.

    The aim of these materials is to interest students in jobs related to Alaska's natural resources. They coordinate with the Sea Week curriculum and the Alaska vocational state model curriculum in renewable natural resources in agriculture. Each of the 2-page career profiles includes a brief description of a person's job along with that person's…

  20. 76 FR 63801 - Fire Prevention Week, 2011

    Science.gov (United States)

    2011-10-13

    ... Proclamation Fires, whether caused by people or nature, can have devastating effects. Hundreds of thousands of... practice fire safety throughout the year. This year's Fire Prevention Week theme, ``Protect Your Family... mowing dry grasses to two inches or less, and by clearing brush, leaves, green grass, and lumber from...

  1. 76 FR 29139 - World Trade Week, 2011

    Science.gov (United States)

    2011-05-19

    ... full resources of the Federal Government behind America's businesses, large and small, and help them... Trade Week, 2011 By the President of the United States of America A Proclamation American businesses embody the ingenuity and entrepreneurship that has defined our Nation since its founding, and they...

  2. 75 FR 29393 - Small Business Week, 2010

    Science.gov (United States)

    2010-05-26

    ... small business owners acquire loans and hire workers. This week, we celebrate the role of entrepreneurs.... They are the backbone of our Nation's economy, they employ tens of millions of workers, and, in the..., and gives entrepreneurs the security they need to innovate and take risks. We have also enacted new...

  3. 78 FR 30729 - World Trade Week, 2013

    Science.gov (United States)

    2013-05-22

    ... historic trade agreements and enforcing trade rights so American workers can compete on a level playing... creates jobs and grows our economy. During World Trade Week, we recognize workers, growers, and entrepreneurs nationwide who share that ambition, and we rededicate ourselves to advancing it in the year ahead...

  4. 75 FR 71519 - National Family Week, 2010

    Science.gov (United States)

    2010-11-24

    ..., educational, and child care support for families throughout the country. This year, I was proud to sign the... communities, shaping the development of our society, instilling values in us, and impacting our lives with... National Family Week, we recognize the importance of the family unit in helping all Americans reach their...

  5. 75 FR 71005 - American Education Week, 2010

    Science.gov (United States)

    2010-11-22

    ... college graduates of any country across the globe by the year 2020. Educators and school employees must... democracy, and to succeed in college, career, and life. This week, let us reaffirm the importance of... sixteenth day of November, in the year of our Lord two thousand ten, and of the Independence of the United...

  6. Critical Evaluation of 4-Week Incubation for Fungal Cultures: Is the Fourth Week Useful?

    Science.gov (United States)

    Labarca, Jaime A.; Wagar, Elizabeth A.; Grasmick, Ann E.; Kokkinos, Heidi M.; Bruckner, David A.

    1998-01-01

    To determine the benefit of a 4-week incubation for mycology cultures, we evaluated all positive cultures during the fourth week of incubation in a 1-year period. Of 3,855 positive mycology cultures (yeast, 82%; molds, 18%), 62 (1.6%) were positive during the fourth week (yeast, 42%; molds, 58%). Only 15 of the 62 cultures (24%) were considered clinically relevant (2 isolates from invasive fungal infection and 13 isolates from cutaneous mycosis). With the exception of those from skin samples, isolates recovered during the fourth week are rarely important for patient care. PMID:9817896

  7. Carboplatin plus paclitaxel once a week versus every 3 weeks in patients with advanced ovarian cancer (MITO-7): a randomised, multicentre, open-label, phase 3 trial.

    Science.gov (United States)

    Pignata, Sandro; Scambia, Giovanni; Katsaros, Dionyssios; Gallo, Ciro; Pujade-Lauraine, Eric; De Placido, Sabino; Bologna, Alessandra; Weber, Beatrice; Raspagliesi, Francesco; Panici, Pierluigi Benedetti; Cormio, Gennaro; Sorio, Roberto; Cavazzini, Maria Giovanna; Ferrandina, Gabriella; Breda, Enrico; Murgia, Viviana; Sacco, Cosimo; Cinieri, Saverio; Salutari, Vanda; Ricci, Caterina; Pisano, Carmela; Greggi, Stefano; Lauria, Rossella; Lorusso, Domenica; Marchetti, Claudia; Selvaggi, Luigi; Signoriello, Simona; Piccirillo, Maria Carmela; Di Maio, Massimo; Perrone, Francesco

    2014-04-01

    Carboplatin plus paclitaxel administered every 3 weeks is standard first-line chemotherapy for patients with advanced ovarian cancer. A weekly paclitaxel schedule combined with carboplatin every 3 weeks prolonged progression-free survival and overall survival in a Japanese phase 3 trial. The aim of our study was to assess whether a weekly schedule of carboplatin plus paclitaxel is more effective than the same drugs given every 3 weeks. We did a multicentre, randomised, phase 3 study at 67 institutions in Italy and France. Women with FIGO stage IC-IV ovarian cancer, an ECOG performance status of 2 or lower, and who had never received chemotherapy were randomly allocated in a 1:1 ratio to receive either carboplatin (AUC 6 mg/mL per min) plus paclitaxel (175 mg/m(2)) every 3 weeks for six cycles or carboplatin (AUC 2 mg/mL per min) plus paclitaxel (60 mg/m(2)) every week for 18 weeks. Randomisation was done by computer-based minimisation, stratified by centre, residual disease after surgery, and ECOG performance status. The study was not blinded. Coprimary endpoints were progression-free survival and quality of life (assessed by the Functional Assessment of Cancer Therapy Ovarian Trial Outcome Index [FACT-O/TOI] score), and analysis was by modified intention to treat. This report presents the final analysis. The study is registered with ClinicalTrials.gov, number NCT00660842. 822 patients were enrolled into the study between Nov 20, 2008, and March 1, 2012; 12 withdrew their consent immediately after randomisation and were excluded, and 810 were eligible for analysis. 404 women were allocated treatment every 3 weeks and 406 were assigned to the weekly schedule. After median follow-up of 22·3 months (IQR 16·2-30·9), 449 progression-free survival events were recorded. Median progression-free survival was 17·3 months (95% CI 15·2-20·2) in patients assigned to treatment every 3 weeks, versus 18·3 months (16·8-20·9) in women allocated to the weekly schedule

  8. Avaliação dos fatores associados ao estado nutricional na idade corrigida de termo em recém-nascidos de muito baixo peso Evaluation of the nutritional status at 40 weeks corrected gestational age in a cohort of very low birth weight infants

    Directory of Open Access Journals (Sweden)

    Nicole M. Gianini

    2005-02-01

    Full Text Available OBJETIVO: Avaliar a adequação do peso ao termo em uma coorte de recém-nascidos com peso de nascimento menor que 1.500 g e correlacioná-la a variáveis clínicas e nutricionais. MÉTODOS: Estudo longitudinal onde recém-nascidos de muito baixo peso de oito hospitais (divididos em duas categorias: tipo I - aporte nutricional agressivo; tipo II - outras práticas foram acompanhados prospectivamente de novembro de 1999 a abril de 2000. O estado nutricional foi avaliado pelo escore z, sendo considerado como desnutrição o escore z menor ou igual a -2, segundo a curva do Canadian Perinatal Surveillance System. Os dados foram analisados por meio de regressão linear múltipla e regressão logística. Este estudo foi aprovado pelo Comitê de Ética em Pesquisa. RESULTADOS: 63% da população estudada (126/200 foi classificada como desnutrida ao termo. O peso ao termo apresentou correlação negativa com o tempo de internação, com a idade gestacional ao nascimento, com o tempo para a recuperação do peso de nascimento e com o clinical risk index for babies (p OBJECTIVE: To evaluate the nutritional status at term of a cohort of newborn babies with birth weights of less than 1,500 g and to correlate this with nutritional practices and clinical variables. METHODS: Very low birth weight infants admitted to eight neonatal intensive care units from November 1999 to April 2000 were studied prospectively. The units were defined as Type I if they employed aggressive nutritional support techniques and Type II if other nutritional practices were used. Babies' were defined as malnourished if their z-score for weight was less than or equal to -2 on the Canadian Perinatal Surveillance System growth curves. Data was analyzed using multivariate linear regression and logistic regression. The study was approved by the Committee for Ethics in Research. RESULTS: Sixty-three percent (126/200 of the study population were classed as being malnourished at term. Weight

  9. Intracorneal blood removal six weeks after canaloplasty

    Directory of Open Access Journals (Sweden)

    Alberto Rossetti

    2013-01-01

    Full Text Available In a 71-year-old patient with bilateral open-angle glaucoma, intracorneal blood was found after a canaloplasty procedure in the right eye. Six weeks after surgery on ultrasound biomicroscopy examination, liquified blood and blood clots could be observed nasally in the deep corneal stroma close to the Descemet′s membrane. The intracorneal blood was washed out with balanced saline solution following deep corneal incision and lamellar dissection. Descemet′s membrane was reattached with air injection into the anterior chamber. Two months later, visual acuity improved to 20/50, intraocular pressure was 16 mm Hg without medication and confocal microscopy showed deep stromal folds and limited endothelial cell loss. Viscoelastic entering the cornea at Schwalbe′s line and reflux of blood from the collector channels to Schlemm′s canal can account for corneal hematoma. Even six weeks after canaloplasty, successful blood removal could be fulfilled without rupturing the Descemet′s membrane.

  10. Vehicle Technologies’ Fact of the Week 2013

    Energy Technology Data Exchange (ETDEWEB)

    Davis, Stacy Cagle [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Diegel, Susan W. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Moore, Sheila A. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Boundy, Robert Gary [Roltek, Inc., Clinton, TN (United States)

    2014-04-01

    Each week the U.S. Department of Energy’s Vehicle Technology Office (VTO) posts a Fact of the Week on their website: http://www1.eere.energy.gov/vehiclesandfuels/ . These Facts provide statistical information, usually in the form of charts and tables, on vehicle sales, fuel economy, gasoline prices, and other transportation-related trends. Each Fact is a stand-alone page that includes a graph, text explaining the significance of the data, the supporting information on which the graph was based, and the source of the data. A link to the current week’s Fact is available on the VTO homepage, but older Facts are archived and still available at: http://www1.eere.energy.gov/vehiclesandfuels/facts/. This report is a compilation of the Facts that were posted during calendar year 2013. The Facts were written and prepared by staff in Oak Ridge National Laboratory's Center for Transportation Analysis.

  11. Medical image of the week: tracheal perforation

    Directory of Open Access Journals (Sweden)

    Parsa N

    2014-12-01

    Full Text Available A 45 year old Caucasian man with a history of HIV/AIDS was admitted for septic shock secondary to right lower lobe community acquired pneumonia. The patient’s respiratory status continued to decline requiring emergency intubation in a non-ICU setting. Four laryngoscope intubation attempts were made including an inadvertent esophageal intubation. Subsequent CT imaging revealed a tracheal defect (Figure 1, red arrow with communication to the mediastinum and air around the trachea consistent with pneumomediastinum (Figure 2, orange arrow and figure 3, yellow arrow. Pneumopericardium (figure 4, blue arrow was also evident post-intubation. The patient’s hemodynamic status remained stable. Two days following respiratory intubation subsequent chest imaging revealed resolution of the pneumomediastinum and pneumopericardium and patient continued to do well without hemodynamic compromise or presence of subcutaneous emphysema. Post-intubation tracheal perforation is a rare complication of traumatic intubation and may be managed with surgical intervention or conservative treatment (1.

  12. STATUS REPORT

    Indian Academy of Sciences (India)

    First page Back Continue Last page Graphics. STATUS REPORT. Raman scattering observed – 90, 135, 180 degrees and back scattering. Traditionally specific angle dependence to learn about polarization response. Learn molecular information from the surface or materials just below the surface (upto 12 mm depth) ...

  13. Compliance status

    International Nuclear Information System (INIS)

    Black, D.G.

    1995-01-01

    This section of the 1994 Hanford Site Environmental Report summarizes the activities conducted to ensure that the Hanford Site is in compliance with federal environmental protection statutes and related Washington State and local environmental protection regulations and the status of Hanford's compliance with these requirements. Environmental permits required under the environmental protection regulations are discussed under the applicable statute

  14. The Effects of a 12-Week Walking Program on Community-Dwelling Older Adults

    Science.gov (United States)

    Cheng, Shun-Ping; Tsai, Tzu-I; Lii, Yun-Kung; Yu, Shu; Chou, Chen-Liang; Chen, I-Ju

    2009-01-01

    Walking is a popular and easily accessible form of physical activity. However, walking instruction for older adults is based on the evidence gathered from younger populations. This study evaluated walking conditions, strength, balance, and subjective health status after a 12-week walking-training program in community-dwelling adults greater than…

  15. WEEKLY BULLETIN PUBLICATION Jeûne genevois - Weekly Bulletin nr 37/2000

    CERN Multimedia

    Section Media & Publications; Tél. 73830; Media & Publication Section; ETT Division; Tel. 73830

    2000-01-01

    As Thursday 7 September is a Holiday (Jeûne genevois), material for publication in Weekly Bulletin nr 37/2000, to appear on Friday 8 September and covering the week of Monday 11 September, should reach us one day earlier than usual, I.E. by noon on Monday 4 September. Thank for your understanding.

  16. Winter fuels report. Week ending, January 26, 1996

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-01-23

    The Winter Fuels Report is intended to provide concise, timely information to the industry, the press, policymakers, consumers analysts, and State and local governments on the following topics: (1) distillate fuel oil net production, imports and stocks on a U.S. level and for all Petroleum Administration for Defense Districts (PADD) and product supplied on a U.S. level; (2) propane net production, imports and stocks on a U.S. level and for PADD`s I, II, and III; (3) natural gas supply and disposition and underground storage for the U.S. and consumption for all PADD`s; as well as selected National average prices; (4) residential and wholesale pricing data for heating oil and propane for those States participating in the joint Energy Information Administration (EIA)/State Heating Oil and Propane Program; (5) crude oil and petroleum price comparisons for the U.S. and selected cities; and (6) a 6-10 Day and 30-Day outlook for temperature and precipitation and U.S. total heating degree-days by city. The distillate fuel oil and propane supply data are collected and published weekly. The data are based on company submissions for the week ending 7:00 a.m. for the preceding Friday. Weekly data for distillate fuel oil are also published in the Weekly Petroleum Status Report. Monthly data for distillate fuel oil and propane are published in the Petroleum Supply Monthly. The residential pricing information is collected by the EIA and the State Energy Offices on a semimonthly basis for the EIA/State Heating Oil and Propane Program. The wholesale price comparison data are collected daily and are published weekly. Residential heating fuel prices are derived from price quotes for home delivery of No. 2 fuel oil and propane. As such, they reflect prices in effect on the dates shown. Wholesale heating oil and propane prices are estimates using a sample of terminal quotes to represent average State prices on the dates given.

  17. A busy week for Arts@CERN

    CERN Multimedia

    Antonella Del Rosso

    2015-01-01

    Last week, Semiconductor – the winners of the Collide@CERN Ars Electronica award for 2015 – and artists Francesco Mariotti and José­-Carlos Mariátegui visited CERN and met the scientists.   Ruth Jarman (left) and Joe Gerhardt (right) of Semiconductor with Peter Jenni, one of the scientists they met during their visit to ATLAS.   Just a few weeks ago, Ruth Jarman and Joe Gerhardt, two English artists collaborating under the name Semiconductor, were awarded the Collide@CERN Ars Electronica prize for 2015. Last week, they came on their first visit to CERN to meet the scientists and select their scientific partner in preparation for their residency. They will soon begin a two-month residency at CERN before going to Linz (Austria), where they will spend a month at the Ars Electronica Futurelab. During their residency, the artists aim to create a digital artwork elaborating on the n...

  18. Cutaneous reaction associated with weekly docetaxel administration.

    Science.gov (United States)

    Chew, Lita; Chuen, Vivianne Shih Lee

    2009-03-01

    Docetaxel-based chemotherapy will remain clinically relevant and many of our patients will continue to receive the drug. In a recent phase 2 study of docetaxel 35 mg/m2 (weekly) in patients with metastatic breast cancer, the incidence of grade 3 cutaneous toxicity is 19%. The skin toxicity observed consists of limb/palmar-plantar erythematous reactions, or fixed-plaque erythrodysesthesia. Case series or reports have reported varied manifestations of skin reactions and include erythema multiforme, nail changes (onycholysis, pigmentation, paronychia), scleroderma, supravenous discoloration, radiation recall dermatitis, and flagellate erythema. We would like to report four patients with cutaneous reactions resulting from weekly administration of docetaxel. All cases are heavily pre-treated patients, receiving docetaxel as second or third line therapy. The cutaneous reactions occur at cycle 5. The time between chemotherapy to development of skin lesions is from 1 to 7 days. Lesions usually resolve with desquamation leaving behind areas with hyper-pigmentation or hypo-pigmentation over a period of 2 to 3 weeks. The management strategies include hand elevation, warm or cold compresses, topical and/or systemic antibiotics, topical and/or systemic corticosteroids, and cessation of drug. There is a need for a systematic approach to manage these cutaneous reactions. Oncology trained pharmacists play vital roles in assessing, managing, documenting and patient education.

  19. Report from the June Trigger and Physics Week

    CERN Multimedia

    Chris Bee

    The week of June 4th saw the 5th ATLAS Trigger and Physics week at CERN. The meeting, bringing together people working in the trigger, data preparation, detector combined-performance and physics groups, aimed at focusing work and discussions on preparing ATLAS for first data-taking. The meeting started on Monday afternoon with a set of plenary presentations on topics ranging from software status and validation, the ATLAS analysis model and its implications for the computing model, and initial ideas for trigger menus for the expected LHC start-up luminosity of 1031cm-2s-1. There was also a report from Peter Jenni on the expected LHC start-up schedule. The participation exceeded the organisers' wildest dreams as the CERN Council Chamber (seating capacity 160) proved woefully inadequate to seat everyone. A packed Council Chamber for the opening plenary Tuesday was dedicated to parallel sessions of the trigger and combined performance groups. A great deal of progress was presented in all areas, notably on...

  20. One-week triple therapy for eradication of helicobacter pylori

    International Nuclear Information System (INIS)

    Shah, N.H.; Shah, M.S.; Khan, I.; Hameed, K.

    2002-01-01

    Objective: The optimum therapy for Helicobacter pylori infection is yet to be defined in Pakistan despite a high prevalence of helicobacter associated diseases in this community. The most popular and effective regimen was therefore chosen among the currently recommended combinations used worldwide to document its efficacy in our symptomatic Helicobacter positive dyspeptic patients. Design: It was a prospective, non-randomized study. Place and duration of Study: The study lasted from January 1998 till June 1999 at the Postgraduate Institute, Government Lady Reading Hospital and Fauji Foundation Hospital, Peshawar. Subjects and Methods: Consecutive dyspeptic patients with peptic ulcer disease as well as non ulcer dyspepsia with a positive H. pylori status on histology from the specimens obtained from the antral region of the stomach, who consented to take part in the study were enrolled. They were given omeprazole 20 mg bd, clarithromycin 500 mg bd. And amoxycillin 1 gm bd for one week. One group comprised patients with confirmed peptic ulcer disease while the second group comprised patients with macroscopic/microscopic antral gastritis. Patients with peptic ulcer disease were given additional course of omerprazol for another 4 weeks to ensure healing of their ulcers. All patients were re scoped after stopping all drugs and their H. pylori status re-assessed on histology. Results: A total of 84 patients consented to enter the study. Fifty-nine were males and twenty-five were females. Fifty-eight patients completed the study while others were lost followup. There were no dropouts due to side effects of the drugs. Sixteen patients had peptic ulcer disease while 68 had macroscopic/microscopic active antral gastric only. The Helicobacter pylori eradication has been successful in only 12 patients giving a cure rate of 20.60% as determined per protocol analysis. The eradication rates were disappointingly low in both groups. Conclusion: The results are extremely

  1. Weekly supplementation with iron and vitamin A during pregnancy increases hemoglobin concentration but decreases serum ferritin concentration in Indonesian pregnant women

    NARCIS (Netherlands)

    Muslimatun, S.; Schmidt, M.K.; Schultink, W.; West, C.E.; Hautvast, J.G.A.J.; Gross, R.; Muhilal,

    2001-01-01

    We investigated whether weekly iron supplementation was as effective as the national daily iron supplementation program in Indonesia in improving iron status at near term in pregnancy. In addition, we examined whether weekly vitamin A and iron supplementation was more efficacious than weekly

  2. Developmental Scores at 1 Year With Increasing Gestational Age, 37–41 Weeks

    Science.gov (United States)

    Rose, Olga; Blanco, Estela; Martinez, Suzanna M.; Sim, Eastern Kang; Castillo, Marcela; Lozoff, Betsy; Vaucher, Yvonne E.

    2013-01-01

    OBJECTIVE: To examine the relationship between gestational age and mental and psychomotor development scores in healthy infants born between 37 and 41 weeks. METHODS: The cohort included 1562 participants enrolled during infancy in an iron deficiency anemia preventive trial in Santiago, Chile. All participants were healthy, full-term (37–41 weeks) infants who weighed 3 kg or more at birth. Development at 12 months was assessed using the Bayley Scales of Infant Development. Using generalized linear modeling, we analyzed the association between gestational age and 1-year-old developmental status, taking into account potential confounders including birth weight percentile, gender, socioeconomic status, the home environment, iron status, and iron supplementation. RESULTS: For each additional week of gestation, the Mental Development Index increased by 0.8 points (95% confidence interval = 0.2–1.4), and the Psychomotor Development Index increased by 1.4 points (95% confidence interval = 0.6–2.1) controlling for birth weight percentile, gender, socioeconomic status, and home environment. CONCLUSIONS: In a large sample of healthy full-term infants, developmental scores obtained using the Bayley Scales of Infant Development at 12 months increased with gestational age (37–41 weeks). There is increasing evidence that birth at 39 to 41 weeks provides developmental advantages compared with birth at 37 to 38 weeks. Because cesarean deliveries and early-term inductions have increased to 40% of all births, consideration of ongoing brain development during the full-term period is an important medical and policy issue. PMID:23589812

  3. Environmental risk assessment of the polycyclic musks AHTN and HHCB according to the EU-TGD

    NARCIS (Netherlands)

    Plassche EJ van de; Balk F; CSR

    1997-01-01

    An environmental risk assessment has been carried out for the polycyclic musks AHTN and HHCB according to the EU Technical Guidance Document for Environmental Risk Assessment for New and Existing Substances. AHTN and HHCB are used in fragrances for cosmetics and detergents. Both substances are high

  4. Comparing maternal breastfeeding self-efficacy during first week and sixth week postpartum

    OpenAIRE

    Pakseresht, Sedighe; Pourshaban, Farzane; khalesi, Zahra Bostani

    2017-01-01

    Introduction The ideal nourishment for the first 12 months of a child?s life comes from breastfeeding its mother?s milk, and maternal self-efficacy is one factor which affects breastfeeding duration. Therefore, the present study aimed to compare the maternal breastfeeding self-efficacy during the first week and sixth-week postpartum. Methods This descriptive, analytical study was conducted on 767 women referring to the Family Health Research Center of Rasht in 2014. Mothers were selected thro...

  5. Medical image of the week: bronchogenic cysts

    Directory of Open Access Journals (Sweden)

    Sears SP

    2018-03-01

    Full Text Available Bronchogenic cysts are congenital foregut malformations forming from abnormal budding of the bronchial tree between the 4th and 6th weeks of embryonic development. While identified primarily in children, the cysts are often asymptomatic and may not be identified until adulthood. Most (70% are within the middle mediastinum and contain fluid or proteinaceous material. When involving the parenchyma, they generally do not communicate with the tracheobronchial tree. Communication with the airways may develop following infection, procedures, or trauma and may result in lesions with an air-fluid level (Figures 1 and 2. Bronchogenic cysts may be complicated by infection, bleeding, fistula formation, or most concerning, by malignant transformation. Unless the cyst contains air, it may manifest as a solitary pulmonary nodule on plain radiographs. Computed tomography or T2-weighted MRI images are used to confirm the diagnosis.

  6. Medical image of the week: DAH

    Directory of Open Access Journals (Sweden)

    Whitmore SP

    2013-03-01

    Full Text Available A 59 year old female was admitted to the ICU with hypoxemic respiratory failure and a clinical picture of ARDS (Figure 1, requiring intubation and mechanical ventilation. She underwent bone marrow and renal transplantation several years prior for multiple myeloma and myeloma kidney, respectively. She had been restarted on lenalidomide one month prior to presentation. She was also taking tacrolimus, mycophenolate, prophylactic antimicrobials, warfarin for deep venous thrombosis, and aspirin for coronary artery disease. Emergent bronchoscopy with bronchoalveolar lavage revealed progressively bloodier specimens (Figure 2 consistent with diffuse alveolar hemorrhage (DAH. Further work-up was negative for vasculitis. Her lenalidomide, anticoagulation, and trimethoprim/sulfamethoxazole was stopped. She was started on high dose steroids and improved over 2 weeks.

  7. Medical image of the week: empyema

    Directory of Open Access Journals (Sweden)

    Young JR

    2013-11-01

    Full Text Available A 71 year-old man with chronic obstructive pulmonary disease (COPD presents to the emergency department complaining of dyspnea after recent admission for pneumonia. Chest CT shows a low density collection in the right lung suggesting necrosis (Figure 1. A CT obtained 1 week after admission (Figure 2 shows progression to empyema. Management of empyema can be difficult. If the fluid cannot be removed with a therapeutic thoracentesis, a chest tube should be inserted and consideration be given to the intrapleural instillation of fibrinolytics (1. If the loculated effusion persists, the patient should be subjected to video-assisted thoracoscopic surgery. If the lung cannot be expanded with this procedure, a full thoracotomy with decortication should be performed. The definitive procedure should be performed within fourteen days.

  8. Status of the SOFIA Observatory

    Science.gov (United States)

    Roellig, Thomas L.

    2015-01-01

    The SOFIA observatory has been in routine science operations since returning in January from a 6 month-long heavy maintenance period for the aircraft and the telescope assembly. These operations include a successful 6 week deployment to the Southern hemisphere. This presentation will provide an update to the current operational status of the SOFIA observatory, concentrating on the improvements and upgrades that have been implemented since the heavy maintenance period.

  9. Changes in cervical cancer screening behavior for women attending Pap Test Week clinics.

    Science.gov (United States)

    Poliquin, V; Decker, K; Altman, Ad; Lotocki, R

    2013-01-01

    This retrospective study of all women who accessed the 2006 Manitoba Pap Test Week clinics was designed to determine factors associated with inadequate cervical cancer screening and changes in cervical cancer screening behavior. Data were acquired using the CervixCheck Manitoba registry and an ancillary database of demographic information collected from clinic attendees. The study included 1124 women. Of these, 53% (n = 598) were under-screened (no Pap test in the previous 2 years) prior to accessing the clinics. Logistic regression analyses demonstrated that older age (odds ratio [OR] = 1.02, 95% confidence interval [CI] 1.01-1.03), no doctor (OR = 1.4, 95% CI 1.05-1.54), and living in Canada Pap Test Week clinics. Thirty-seven percent (n = 223) of under-screened women demonstrated improved screening status subsequent to the 2006 Pap Test Week (had a subsequent Papanicolaou [Pap] test performed within 2 years) and these women were more likely to live in an urban setting (P = 0.003), be younger (P Pap test result in 2006 (P Pap test performed at a Pap Test Week clinic compared to having a Pap test performed elsewhere (37% versus 60%, P Pap Test Week clinics whose screening status might be most modifiable.

  10. Medical image of the week: headcheese sign

    Directory of Open Access Journals (Sweden)

    Adial A

    2018-04-01

    Full Text Available No abstract available. Article truncated at 150 words. A 95-year-old woman with a past medical history of breast cancer and mastectomy presented with fevers, cough productive of sputum and progressive dyspnea for 2 weeks. She denies any recent travel or sick contacts but has bird at home since last 10 years. She was afebrile but tachypneic with respiratory rate of 25 and sPO2 of 86% on room air. Her initial chest examination reveals coarse rhonchi in both lungs. Labs were significant for a sodium of 118 mEq/L, leukocytosis to 18,000 cells/mcL without peripheral eosinophilia. Arterial blood gas showed pO2 of 55 mm Hg, pCO2 of 48 mm Hg and pH of 7.44. An initial chest X-ray was positive for extensive bilateral pulmonary infiltrates predominantly in the mid and lower lungs with areas of airspace consolidation. Her urine Streptococcus pneumoniae antigen was negative as well as rapid influenza and a respiratory syncytial virus panel. The high resolution thoracic CT …

  11. The new Bulletin arrives in two weeks

    CERN Multimedia

    2006-01-01

    In May, you will discover a redesigned CERN Bulletin. Starting with the first May issue (No. 19-20/2006), the format of the CERN Bulletin will change completely. The page layout will be more attractive, reminiscent of a proper newspaper, with pictograms to identify the different sections. The information provided will also be more visible. The Bulletin was much in need of a makeover as its current layout dates back to 1976! The introduction of the new format will coincide with the introduction of a new means of distribution. You will still receive the elctronic version of the Bulletin every week directly on your computer. However, in order to avoid the waste from the dozens of copies that linger unread in people's mailboxes, the paper version will be available at a series of distribution points around the Laboratory. You will find the Bulletin along with the Staff Association newsletter at the cafeteria closest to your office. The Bulletin will be available from the following distribution points: On the M...

  12. Medical image of the week: aspergilloma

    Directory of Open Access Journals (Sweden)

    Hsu W

    2014-05-01

    Full Text Available No abstract available. Article truncated after 150 words. A 69-year-old woman, a current smoker, with very severe chronic obstructive pulmonary disease and prior atypical mycobacterium, was found unresponsive by her family and intubated in the field by emergency medical services for respiratory distress. Her CT thorax showed severe emphysematous disease, apical bullous disease, and a large left upper lobe cavitation with debris (Figure 1. She was treated with broad-spectrum antibiotics and anti-fungal medications. Hemoptysis was never seen. Sputum cultures over a span of two weeks repeatedly showed Aspergillus fumigatus and outside medical records confirmed the patient had a known history of stable aspergilloma not requiring therapy. Aspergillomas usually arises in cavitary areas of the lung damaged by previous infections. The fungus ball is a combination of colonization by Aspergillus hyphae and cellular debris. Individuals with aspergillomas are usually asymptomatic or have mild symptoms (chronic cough and do not require treatment unless it begins to invade into the cavity ...

  13. Medical image of the week: methemoglobinemia

    Directory of Open Access Journals (Sweden)

    Raschke RA

    2018-01-01

    Full Text Available No abstract available. Article truncated at 150 words. A 62-year-old man with a sternal infection post-coronary artery bypass grafting was transferred because of increasing oxygen requirements, decreased mental status and Candida paralopsis fungemia. He had been treated with multiple antibiotics including sulfonamides and had eventually undergone a tracheostomy. Cetacaine was used for complaints of a sore throat. Physical examination showed cyanotic lips and tongue (Figure 1A. Blood drawn was a chocolate brown color (Figure 2. His SpO2 was 88%, however, arterial blood gases showed his SaO2 was 100% and his PaO2 453 mmHg. Co-oximetry showed 26% methemoglobin. He was administered 0.2mL/kg of 1% solution of methylene blue and his cyanosis rapidly cleared (Figure 1B. Methemoglobinemia is a condition characterized by increased quantities of hemoglobin with iron oxidized to the ferric (Fe3+ form (1. Methemoglobin is useless as an oxygen carrier and thus causes a varying degree of cyanosis and hypoxia. It can be genetic but is usually caused …

  14. Medical image of the week: arachnoid cyst

    Directory of Open Access Journals (Sweden)

    Erisman M

    2016-10-01

    Full Text Available No abstract available. Article truncated at 150 words. A 40 year-old woman with adult attention deficit hyperactive and bipolar 1 disorder presents with an altered mental status. Per her family, she had been non-verbal, with reduced oral intake, confusion and sedated for the past three days. Per her husband, she had episodes of diarrhea and abdominal discomfort. She was on multiple medications including ramelteon 8mg nightly, atomoxetine 40mg daily, hydroxyzine 25mg twice daily, bupropion 75mg twice daily and risperidone 2mg daily with recent addition of lithium ER 1200mg/daily started one month prior to presentation with unknown adherence. Upon arrival, vital signs were within normal limits. Physical exam revealed an overweight Caucasian woman with a significant coarse tremor visible at rest, restlessness and diaphoresis. Neurological examination was limited by patient hesitancy, however, it did not demonstrate focal deficits except for altered consciousness with Glasgow Coma Scale of 10. Notable laboratory findings were Na+ 134 mEq/L, K+ 3.2 mEq/L, and ...

  15. Medical image of the week: fat embolism

    Directory of Open Access Journals (Sweden)

    Kim HJ

    2017-12-01

    Full Text Available No abstract available. Article truncated after 150 words. A 74-year-old woman presented to the hospital with a left femoral neck fracture after a fall. The next day she underwent an uneventful left hip hemiarthroplasty. About 3 hours postoperatively, she became lethargic, tachycardic, tachypneic, febrile, and hypotensive. An arterial blood gas analysis revealed mild hypoxemia with PaO2 / FiO2 ratio of 270. Hemoglobin decreased from 9.4g/dL to 7.7g/dL postoperatively. A chest x-ray showed only bibasilar opacities. Sepsis, acute postoperative blood loss anemia, and pulmonary embolism (PE were entertained as a differential diagnosis. The patient was resuscitated with intravenous fluids and packed red blood cells, and was started on broad-spectrum antibiotics. Her hemodynamic status stabilized shortly thereafter. A CT chest with PE protocol and abdomen/pelvis down to thigh level was performed; no PE was identified. It did not show any intraabdominal pathology or signs of hemorrhage. However, it incidentally revealed fat embolus mixed with thrombus in the left common and …

  16. Medical image of the week: necrotizing pancreatitis

    Directory of Open Access Journals (Sweden)

    Desai H

    2015-08-01

    Full Text Available No abstract available. Article truncated after 150 words. A 60-year-old man with a past medical history significant for coronary artery disease status post percutaneous coronary intervention was admitted to Banner University Medical Center for acute pancreatitis complicated by a pericardial effusion requiring pericardiocentesis. The following day, the patient developed severe shortness of breath requiring increasing amounts of supplemental oxygen. The patient was emergently transferred to ICU for noninvasive bilevel positive airway pressure ventilation, but he subsequently required intubation. Throughout his worsening condition, he denied any abdominal pain, only relaying ongoing substernal chest pain. His troponins, however, remained negative and echocardiography failed to show any reaccumulation of the pericardial effusion. CT scan of the chest failed to show any pulmonary embolism. But, CT abdomen displayed acute pancreatitis complicated by peripancreatic gas consistent with necrotizing pancreatitis (Figure 1. Emergent laparotomy was completed. There were no signs of stomach or duodenal perforation. Purulent fluid was removed from the lesser sac and ...

  17. Medical image of the week: septic emboli

    Directory of Open Access Journals (Sweden)

    Malakkla N

    2014-09-01

    Full Text Available No abstract available. Article truncated at 150 words. A 46-year-old man was admitted with altered mental status. His past medical history included HIV/AIDS on HAART therapy, hepatitis B and C, non-Hodgkin's lymphoma (NHL, deep venous thrombosis with insertion of an inferior vena caval filter, and poly-substance abuse. Vitals revealed fever and tachycardia. On exam, he was lethargic and confused, and had bilateral crackles on lung auscultation. Computerized axial tomography (CT of the head was unremarkable and chest X-ray revealed patchy nodular infiltrates in the right upper lobe and bilateral lower lobes. Work up for an infectious cause was initiated including opportunistic infections and he was started on empiric antibiotics for pneumonia. On Day 2, his roommate who came to visit him, revealed that he was recently admitted in another hospital for headache and flu-like symptoms, and discharged with a peripherally inserted central catheter (PICC in place as he was scheduled for a positron emission tomography (PET the next ...

  18. Four Weeks of Mobility After 8 Weeks of Immobility Fails to Restore Normal Motion

    Science.gov (United States)

    Trudel, Guy; Zhou, Jian; Uhthoff, Hans K.

    2008-01-01

    Prolonged immobilization reduces passive range of motion of joints creating joint contractures. Whether and to what extent these iatrogenic contractures can be reduced is unknown. We raised three questions using an animal model: What degree of contracture remains at the end of a defined remobilization period? Do contractures in sham-operated and immobilized joints differ? What is the contribution of the posterior knee capsule in limiting knee extension? We immobilized one knee of 11 adult male rats in flexion to induce a joint contracture; 10 control animals underwent a sham operation. After 8 weeks, the internal fixation device was removed, and the animals were allowed to resume unrestricted activity for 4 weeks at the end of which the knee range of motion was measured with standardized torques. The mean flexion contracture was higher in the immobilized group (51.9° ± 2.8°) than in the sham-operated group (18.9° ± 2.1°). Eighty-eight percent of the contractures remained in the immobilized group after dividing skin and muscle, suggesting an important contribution of the posterior knee capsule in limiting knee mobility. Based on our preliminary study the range of motion of rat knees immobilized for 8 weeks remained substantially reduced after a 4-week period of unassisted remobilization. PMID:18299947

  19. One Week, Many Ripples: Measuring the Impacts of the Fall Reading Week on Student Stress

    Science.gov (United States)

    Poole, Heather; Khan, Ayesha; Agnew, Michael

    2017-01-01

    More and more Canadian post-secondary institutions are introducing a fall break into their term calendars. In 2015, a full week fall break was introduced at our university in order to enhance academic performance and improve mental health amongst students. Our interdisciplinary team surveyed undergraduate students at our university about their…

  20. Medical image of the week: acute amiodarone pulmonary toxicity

    Directory of Open Access Journals (Sweden)

    Mazursky K

    2015-10-01

    Full Text Available No abstract available. Article truncated after 150 words. A 71 year old man with a medical history significant for chronic obstructive pulmonary disease, coronary artery disease with post-operative status coronary artery bypass grafting, heart failure with reduced ejection fraction (25% and atrial fibrillation/flutter underwent an elective ablation of the tachyarrhythmia at another facility and was prescribed amiodarone post procedure. He started complaining of cough and dyspnea one day post procedure and was empirically treated with 2 weeks of broad spectrum antibiotics. He subsequently was transferred to our facility due to worsening symptoms. He also complained of nausea, anorexia with resultant weight loss since starting amiodarone, which was stopped 5 days prior to transfer. Infectious work up was negative. On arrival to our facility, he was diagnosed with small sub-segmental pulmonary emboli, pulmonary edema and possible acute amiodarone toxicity. His was profoundly hypoxic requiring high flow nasal cannula or 100% non-rebreather mask at all times. His symptoms persisted despite ...

  1. Night work, long work weeks, and risk of accidental injuries. A register-based study.

    Science.gov (United States)

    Larsen, Ann D; Hannerz, Harald; Møller, Simone V; Dyreborg, Johnny; Bonde, Jens Peter; Hansen, Johnni; Kolstad, Henrik A; Hansen, Åse Marie; Garde, Anne Helene

    2017-11-01

    Objectives The aims of this study were to (i) investigate the association between night work or long work weeks and the risk of accidental injuries and (ii) test if the association is affected by age, sex or socioeconomic status. Methods The study population was drawn from the Danish version of the European Labour Force Survey from 1999-2013. The current study was based on 150 438 participants (53% men and 47% women). Data on accidental injuries were obtained at individual level from national health registers. We included all 20-59-year-old employees working ≥32 hours a week at the time of the interview. We used Poisson regression to estimate the relative rates (RR) of accidental injuries as a function of night work or long work weeks (>40 hours per week) adjusted for year of interview, sex, age, socioeconomic status (SES), industry, and weekly working hours or night work. Age, sex and SES were included as two-way interactions. Results We observed 23 495 cases of accidental injuries based on 273 700 person years at risk. Exposure to night work was statistically significantly associated with accidental injuries (RR 1.11, 99% CI 1.06-1.17) compared to participants with no recent night work. No associations were found between long work weeks (>40 hours) and accidental injuries. Conclusion We found a modest increased risk of accidental injuries when reporting night work. No associations between long work weeks and risk of accidental injuries were observed. Age, sex and SES showed no trends when included as two-way interactions.

  2. Current status of developmental neurotoxicity: regulatory view

    DEFF Research Database (Denmark)

    Hass, Ulla

    2003-01-01

    . Until recently, however, developmental neurotoxicity testing of industrial chemicals has not been a clear regulatory requirement in EU, probably due to the lack of an accepted OECD TG. The revised EU Technical Guidance Document for Risk Assessment (EU-TGD) has now included the OECD draft TG 426...... in the testing strategy for new and existing substances, and biocides. Hopefully, this will lead to an improved database for risk assessment of potential developmental neurotoxicants. However, the regulatory authorities and toxicologists will also be faced with the challenge that decisions have to be made......The need for developmental neurotoxicity testing has been recognized for decades and guidelines are available, as the USEPA guideline and the OECD draft TG 426. Regulatory testing of industrial chemicals for developmental neurotoxicity is required to some extent, especially for pesticides in the US...

  3. Intracranial Hemorrhage Following a 3-week Headache

    Directory of Open Access Journals (Sweden)

    John Jiao

    2017-01-01

    Full Text Available History of present illness: A 35-year-old female presented to the ED with a Glasgow Coma Scale (GCS of 11. Per her boyfriend, the patient was having headaches for the past 3 weeks. She was initially taken to an outside hospital where her GCS was reported as 13. A non-contrast head computed tomography (CT revealed a large lobar intraparenchymal hemorrhage within the left frontal parietal lobe with midline shift. Upon examination, vitals were notable for blood pressure of 209/88mmHg, and her left pupil was fixed and dilated. The patient had extension of her right arm to noxious stimuli, paralysis of her right leg, and purposeful movement of the left arm and left leg. The patient was started on a nicardipine drip in the ED and subsequently taken to the operating room for a decompressive craniectomy. Significant findings: The patient’s head CT showed a significant area of hyperdensity consistent with an intracranial hemorrhage located within the left frontal parietal lobe (red arrow. Additionally, there is rightward midline shift up to 1.1cm (green arrow and entrapment of the right lateral ventricle (blue arrow. Discussion: Intraparenchymal hemorrhage (IPH is associated with high morbidity and mortality. Although the mortality for subarachnoid hemorrhage (SAH has declined steadily over the past several decades, the mortality for IPH mortality has not significantly.1 One of the most serious considerations when treating a patient with IPH is the management of intracranial pressure (ICP.2 Once an IPH is identified, immediate steps should be taken to bring ICP within acceptable levels including elevating the head of the bed to 30 degrees, sedation, and controlling hypertension with medications.2-3 Even with early and aggressive care, the prognosis for IPH remains poor; the 30-day mortality rate for IPH is estimated to be less than 50%, and a 2010 systematic review estimated only 12-39% of IPH patients achieve independent function.4-5 Predictors of

  4. Physical activity initiated by employer and its health effects; an eight week follow-up study

    Directory of Open Access Journals (Sweden)

    Marit Skogstad

    2016-05-01

    favorable lipid status compared to lower weekly activity. During the 8-week follow-up of an employer initiated exercise program VO2max increased, while total cholesterol and LDL were reduced. Trial registration Current Controlled Trials ISRCTN13033050 . Registered 21 August 2015.

  5. Trichophyton rubrum onychomycosis in an 8-week-old infant

    Directory of Open Access Journals (Sweden)

    Vinod K Khurana

    2011-01-01

    Full Text Available An 8-week-old infant presented with 7 weeks history of nail involvement and discoloration. Lesions started over the middle fingernail of right hand at 1 week of age, spreading over to other nails within 2 weeks. Only two nails of the feet were spared. On KOH examination, fungal hyphae were seen and culture showed growth of Trichophyton rubrum. The purpose is to report the earliest case of onychomycosis having multiple nail involvement of fingers and toes (18 nails.

  6. Vitamin 0 status of older South Africans

    African Journals Online (AJOL)

    performing outdoor physical activities was low. In most cases, subjects spent less than an hour a week either walking, gardening or participating in a sport. This study found, for the first time, that the elderly coloured population of Cape Town has a high prevalence of suboptimal vitamin 0 status, as determined by serum.

  7. Open Data Poster for Open Access Week - PDF file

    OpenAIRE

    Briney, Kristin

    2013-01-01

    .pdf version of the Open Data/Open Access Week poster.   Illustrator version: http://figshare.com/articles/Open_Data_poster_for_Open_Access_Week/828596 Combined fileset here: http://figshare.com/articles/Open_Data_Poster_for_Open_Access_Week/828597

  8. Open Data poster for Open Access Week - AI file

    OpenAIRE

    Briney, Kristin

    2013-01-01

    Adobe Illustrator (.ai) version of the Open Data/Open Access week poster.   PDF version: http://figshare.com/articles/Open_Data_Poster_for_Open_Access_Week/828595 Combined fileset here: http://figshare.com/articles/Open_Data_Poster_for_Open_Access_Week/828597

  9. Expand Your Child's Vocabulary: A Twelve-Week Plan.

    Science.gov (United States)

    Smith, Carl B.

    This booklet shows parents how to help their children develop a number of strategies for understanding words by working together on a methodical, 12-week program of word study. Sections of the booklet describe the program week by week. The techniques described are: Read and Use Context; Search for Synonyms, Antonyms, Homonyms; Learn Important…

  10. Average Weekly Alcohol Consumption: Drinking Percentiles for American College Students.

    Science.gov (United States)

    Meilman, Philip W.; And Others

    1997-01-01

    Reports a study that examined the average number of alcoholic drinks that college students (N=44,433) consumed per week. Surveys indicated that most students drank little or no alcohol on an average weekly basis. Only about 10% of the students reported consuming an average of 15 drinks or more per week. (SM)

  11. 76 FR 16521 - National Poison Prevention Week, 2011

    Science.gov (United States)

    2011-03-23

    ... March 23, 2011 Part III The President Proclamation 8638--National Poison Prevention Week, 2011 #0; #0..., 2011 National Poison Prevention Week, 2011 By the President of the United States of America A... cases, these tragic incidents are preventable. During National Poison Prevention Week, I encourage all...

  12. Effects of Aerobic Exercise Training on Psychosocial Status and ...

    African Journals Online (AJOL)

    an 8 weeks continuous training (60%‑79% HR max) of between 45 and 60 min, 3 times per week, while the controls group ... Lamina and Okoye: Effects of aerobic exercise training on psychosocial status and serum uric acid in men such as high energy/drive, ..... 20. Crews DJ, Landers DM. A meta‑analytic review of aerobic.

  13. Leadership Status Congruency and Cohesion in Outdoor Expedition Groups

    Science.gov (United States)

    Eys, Mark A.; Ritchie, Stephen; Little, Jim; Slade, Heather; Oddson, Bruce

    2008-01-01

    The purpose of the present study was to examine the relationship between status congruency and group cohesion in outdoor expedition groups in an educational setting. Specifically, three aspects of status congruency were assessed in relation to group cohesion in four adventure canoe groups. The groups participated in 2-week expeditions in the…

  14. Periodontal status during pregnancy and postpartum

    Science.gov (United States)

    2017-01-01

    Objectives Different studies have documented an association between periodontal disease and low birth-weight delivery. Hence, knowledge of periodontal status during pregnancy and postpartum is important in order to reduce the risks of both diseases. This study aimed to analyze periodontal status at successive stages of pregnancy and 3–6 weeks postpartum in women with initial periodontal alterations. Materials and methods Ninety-six pregnant women were examined at 8–10 weeks (pregnancy diagnosis, baseline), 21–23 weeks and 34–36 weeks of gestation and at 40 days postpartum to record plaque scores, clinically assessed gingival inflammation and probing depth (mean depth and % sites with depth >3 mm). Bivariate and multivariate analyses were performed. Type 1 (α) error was established at 0.05 Results Plaque Index increased (p = 0.043) throughout pregnancy (baseline, 42%±0.18); 21–23 weeks, 42.6%±0.14; 34–36 weeks, 45.6%±0.13 and decreased postpartum (44.8%±0–13). Gingival Index increased (ppregnancy (baseline, 56.7%±0.20; 21–23 weeks, 66.36%±0.17; 34–36 weeks, 74.5%±0.18) and decreased postpartum (59.3%±0.21). Probing Depth increased (ppregnancy (baseline, 2.51±0.05; 21–23 weeks, 2.63±0.053; 34–36 weeks 2.81±0.055) and decreased postpartum (2.54±0.049). Percentage of sites with Probing Depth >3 mm increased (ppregnancy (baseline, 17.6%±0.16; 21–23 weeks, 23.9%±0.17; 34–36 weeks, 31.1%±0.17) and decreased postpartum (21.2%±0.17) but remained significantly (p<0.02) higher than at baseline. Conclusion Periodontal status deteriorates during gestation but improves postpartum. PMID:28538740

  15. Weekly Time Course of Neuro-Muscular Adaptation to Intensive Strength Training.

    Science.gov (United States)

    Brown, Niklas; Bubeck, Dieter; Haeufle, Daniel F B; Weickenmeier, Johannes; Kuhl, Ellen; Alt, Wilfried; Schmitt, Syn

    2017-01-01

    Detailed description of the time course of muscular adaptation is rarely found in literature. Thus, models of muscular adaptation are difficult to validate since no detailed data of adaptation are available. In this article, as an initial step toward a detailed description and analysis of muscular adaptation, we provide a case report of 8 weeks of intense strength training with two active, male participants. Muscular adaptations were analyzed on a morphological level with MRI scans of the right quadriceps muscle and the calculation of muscle volume, on a voluntary strength level by isometric voluntary contractions with doublet stimulation (interpolated twitch technique) and on a non-voluntary level by resting twitch torques. Further, training volume and isokinetic power were closely monitored during the training phase. Data were analyzed weekly for 1 week prior to training, pre-training, 8 weeks of training and 2 weeks of detraining (no strength training). Results show a very individual adaptation to the intense strength training protocol. While training volume and isokinetic power increased linearly during the training phase, resting twitch parameters decreased for both participants after the first week of training and stayed below baseline until de-training. Voluntary activation level showed an increase in the first 4 weeks of training, while maximum voluntary contraction showed only little increase compared to baseline. Muscle volume increased for both subjects. Especially training status seemed to influence the acute reaction to intense strength training. Fatigue had a major influence on performance and could only be overcome by one participant. The results give a first detailed insight into muscular adaptation to intense strength training on various levels, providing a basis of data for a validation of muscle fatigue and adaptation models.

  16. Decoupling social status and status certainty effects on health in macaques: a network approach

    Directory of Open Access Journals (Sweden)

    Jessica J. Vandeleest

    2016-09-01

    Full Text Available Background Although a wealth of literature points to the importance of social factors on health, a detailed understanding of the complex interplay between social and biological systems is lacking. Social status is one aspect of social life that is made up of multiple structural (humans: income, education; animals: mating system, dominance rank and relational components (perceived social status, dominance interactions. In a nonhuman primate model we use novel network techniques to decouple two components of social status, dominance rank (a commonly used measure of social status in animal models and dominance certainty (the relative certainty vs. ambiguity of an individual’s status, allowing for a more complex examination of how social status impacts health. Methods Behavioral observations were conducted on three outdoor captive groups of rhesus macaques (N = 252 subjects. Subjects’ general physical health (diarrhea was assessed twice weekly, and blood was drawn once to assess biomarkers of inflammation (interleukin-6 (IL-6, tumor necrosis factor-alpha (TNF-α, and C-reactive protein (CRP. Results Dominance rank alone did not fully account for the complex way that social status exerted its effect on health. Instead, dominance certainty modified the impact of rank on biomarkers of inflammation. Specifically, high-ranked animals with more ambiguous status relationships had higher levels of inflammation than low-ranked animals, whereas little effect of rank was seen for animals with more certain status relationships. The impact of status on physical health was more straightforward: individuals with more ambiguous status relationships had more frequent diarrhea; there was marginal evidence that high-ranked animals had less frequent diarrhea. Discussion Social status has a complex and multi-faceted impact on individual health. Our work suggests an important role of uncertainty in one’s social status in status-health research. This work also

  17. Weekly Cycle of Lightning: Evidence of Storm Invigoration by Pollution

    Science.gov (United States)

    Bell, Thomas L.; Rosenfeld, Daniel; Kim, Kyu-Myong

    2009-01-01

    We have examined summertime 1998 2009 U.S. lightning data from the National Lightning Detection Network (NLDN) to look for weekly cycles in lightning activity. As was found by Bell et al. (2008) for rain over the southeast U.S., there is a significant weekly cycle in afternoon lightning activity that peaks in the middle of the week there. The weekly cycle appears to be reduced over population centers. Lightning activity peaks on weekends over waters near the SE U.S. The statistical significance of weekly cycles over the western half of the country is generally small. We found no evidence of a weekly cycle of synoptic-scale forcing that might explain these patterns. The lightning behavior is entirely consistent with the explanation suggested by Bell et al. (2008) for the cycles in rainfall and other atmospheric data from the SE U.S., that aerosols can cause storms to intensify in humid, convectively unstable environments.

  18. What Is Known and Unknown About Twice-Weekly Hemodialysis

    OpenAIRE

    Obi, Yoshitsugu; Eriguchi, Rieko; Ou, Shuo-Ming; Rhee, Connie M.; Kalantar-Zadeh, Kamyar

    2015-01-01

    © 2015 S. Karger AG, Basel. Background: The 2006 Kidney Disease Outcomes Quality Initiative guidelines suggest twice-weekly or incremental hemodialysis for patients with substantial residual kidney function (RKF). However, in most affluent nations de novo and abrupt transition to thrice-weekly hemodialysis is routinely prescribed for all dialysis-naïve patients regardless of their RKF. We review historical developments in hemodialysis therapy initiation and revisit twice-weekly hemodialysis a...

  19. Concurrence of Serum Creatinine and Albumin With Lower Risk for Death in Twice-Weekly Hemodialysis Patients.

    Science.gov (United States)

    Wang, Jialin; Streja, Elani; Soohoo, Melissa; Chen, Joline L T; Rhee, Connie M; Kim, Taehee; Molnar, Miklos Z; Kovesdy, Csaba P; Mehrotra, Rajnish; Kalantar-Zadeh, Kamyar

    2017-01-01

    Markers of better nutritional status including both higher levels of serum albumin (as a measure of visceral proteins) and creatinine (as a measure of the muscle mass) are associated with lower mortality in conventional (thrice weekly) hemodialysis patients. However, data for these associations in twice-weekly hemodialysis patients, in whom less frequent hemodialysis may confound nutritional predictors, are lacking. We identified 1,113 twice-weekly and matched 4,448 thrice-weekly hemodialysis patients from a large national dialysis cohort of incident hemodialysis patients over 5 years (2007-2011). Mortality risk, adjusted for potential confounders, was examined across two-by-two combinations of serum creatinine (creatinine ≥ 6 mg/dL and albumin ≥ 3.5 g/dL as reference, patients with creatinine creatinine mortality associations between twice-weekly and thrice-weekly hemodialysis patients (P-for-interaction = .7667). Surrogate markers of higher visceral protein and muscle mass combined may confer greatest survival in both twice-weekly and thrice-weekly hemodialysis patients. Copyright © 2016 National Kidney Foundation, Inc. Published by Elsevier Inc. All rights reserved.

  20. Patients' assessment of 4-week recovery after ambulatory surgery.

    Science.gov (United States)

    Brattwall, M; Warrén Stomberg, M; Rawal, N; Segerdahl, M; Jakobsson, J; Houltz, E

    2011-01-01

    patients' own assessment of recovery after ambulatory surgery has not been well studied. The aim was to study patients' self-assessed recovery, the occurrence and time course of post-operative problems in relation to the type of ambulatory surgery. a questionnaire was filled in by 355 patients at five time points: pre-operative, first day at home, 1, 2 and 4 weeks post-operatively. Consecutive patients who underwent either inguinal hernia repair (IHR), arthroscopic procedures (AS) or cosmetic breast augmentation (CBA) were included. unplanned return to hospital was rare (3/355). Health care contacts were noted for 9% of the patients during the first week; a total of 70 contacts occurred during the entire period. Pain was the most frequently reported symptom; 40% of the patients reported pain or mobility problems at 1 week, 28% after 2 weeks and 20% after 4 weeks. Pre-operative pain was associated with an increased level of pain during the early post-operative course, in the recovery room and at 1 week post-operatively. IHR was associated with an overall rapid recovery, while AS patients experienced a slower restitution. All AS patients who reported pain after 4 weeks had reported pain problems already pre-operatively. Pain was not present pre-operatively in the CBA group, but was common at 1 and 2 post-operative weeks and was still reported by 11% at 4 weeks. self-assessed recovery was found to cover several weeks with procedure-specific recovery patterns. Pain and mobility impairment were still frequently reported 4 weeks post-operatively. 2010 The Acta Anaesthesiologica Scandinavica Foundation.

  1. Effects of 16-weeks of Pilates on health perception and sleep quality among elderly women.

    Science.gov (United States)

    Curi, V S; Vilaça, J; Haas, A N; Fernandes, H M

    2018-01-01

    The objective of this study was to determine the effect of 16 weeks of mat-based Pilates training on health perception and sleep quality among elderly women. A randomized and controlled trial was conducted in Caxias do Sul, Brazil, in 2015, in which 61 healthy older women were divided into two groups: experimental group (EG; n=31, average of 64.25 years old, SD 0.14) and control group (CG; n=30, average of 63.75 years old, SD 0.08). The EG participants performed mat-based Pilates exercises twice a week in 60-min sessions, whereas the CG did not train. All participants completed Brazilian-adapted and validated versions of the Pittsburgh Sleep Quality Index (PSQI-BR) and General Health Questionnaire (GHQ-12) at baseline and after 16 weeks. Significant time x group interaction effects were found for the GHQ-12 total score (pPilates EG when compared to the CG. All significant effects were classified as moderate to high. These results indicate that 16 weeks of mat-based Pilates training significantly improves the perceived health status and some sleep quality indices among elderly women. However, more studies are needed to assess the effectiveness of equipment-based Pilates exercises among this population. Copyright © 2017 Elsevier B.V. All rights reserved.

  2. Effect of 12-Week Pilates Trainning on EDSS in Women Suffering fromMultiple Sclerosis

    Directory of Open Access Journals (Sweden)

    Z Shanazari

    2013-04-01

    Full Text Available Abstract Background & aim: Multiple sclerosis is a debilitating disease that strikes the immune system. Multiple sclerosis is a chronic disease which debilitates the nervous system. The study was evaluated the effects of Pilates exercise on women with physical disabilities suffering from multiple sclerosis for 12 weeks .The aim of this study was to investigating the effects of Pilates trainning on EDSS of women suffering from Multiple Sclerosis (MS for 12 weeks. Methods: In the present clinical trial study, 38 patients age 20-40 years (mean disease duration of 8±2 years with multiple sclerosis grade 0-4.5 were selected. The Patients were randomly divided into two groups: experimental and control groups. The training program for pilates, 12 weeks, three sessions a week, with each session consisting of 60 minutes. Patients' physical disability was measured using Krutzke Expanded Disability Status Scale, before and after exercise. Data were analyzed by ANCOVA test. Results: Physical disability scores before and after the exercise in intervention was 47.1 and 37 and in the control group, was 93.1 and 43.1 respectively, which was significantly different in the intervention group before and after training (p<0.05. Conclusion: Pilates training improves the physical disability of MS patients. Therefore, this exercise can be used as a complementary treatment alongside drug treatments. Key Words: Multiple Sclerosis, Women, Pilates, EDSS

  3. Effects of six weeks of detraining on retention of functional fitness of old people after nine weeks of multicomponent training.

    Science.gov (United States)

    Toraman, N F; Ayceman, N

    2005-08-01

    To examine the effects of age on functional fitness after six weeks of detraining. Elderly subjects, aged 60-86 years, completed a nine week multicomponent exercise training programme. They performed the senior fitness test every two weeks during the six week detraining period, and the responses of 12 young-old subjects (YO, aged 60-73 years) and nine older subjects (O, aged 74-86 years) were compared. Functional fitness improved during the exercise training period. Performances in the chair stand and six minute walk for the O group had significantly declined compared with post-training values after two weeks of detraining (pdetraining in both of the groups (pdetraining compared with after four weeks of detraining (pdetraining were lower extremity flexibility after two and four weeks of detraining, and agility/dynamic balance after six weeks of detraining. Changes in lower extremity flexibility, up and go, and six minute walk performances in response to six weeks of detraining are affected by age in elderly adults.

  4. Effect of 8-week exerciseon improving the static and dynamic ...

    African Journals Online (AJOL)

    Before the training program of supinated legs of navicular drop test subjects, static balance and dynamic balance was measured with a force platform. The experimental group carried out exercises program for 8 weeks with a frequency of three times a week on the area of weak muscles and stretched legs, and the control ...

  5. 76 FR 27597 - National Women's Health Week, 2011

    Science.gov (United States)

    2011-05-11

    ... Affordable Care Act became law last year, insurance companies could deny coverage to women due to previous... May 11, 2011 Part V The President Proclamation 8670--National Women's Health Week, 2011 Proclamation... ] Proclamation 8670 of May 6, 2011 National Women's Health Week, 2011 By the President of the United States of...

  6. Markovian Approach for the Analysis and Prediction of Weekly ...

    African Journals Online (AJOL)

    ADOWIE PERE

    ABSTRACT: A stochastic model to study weekly rainfall pattern has been presented in this paper. The Markovian .... The value Pijrepresents the probability that the process will, when in state i,next make .... Denotes the initial state vector, then our First order Markov Chain Model for weekly rainfall amount pattern prediction in ...

  7. Efficiency of twice weekly concurrent training in trained elderly men.

    Science.gov (United States)

    Ferrari, Rodrigo; Kruel, Luiz Fernando Martins; Cadore, Eduardo Lusa; Alberton, Cristine Lima; Izquierdo, Mikel; Conceição, Matheus; Pinto, Ronei Silveira; Radaelli, Régis; Wilhelm, Eurico; Bottaro, Martim; Ribeiro, Jorge Pinto; Umpierre, Daniel

    2013-11-01

    This study compared the effects of different weekly training frequencies on the cardiovascular and neuromuscular adaptations induced by concurrent training in previously trained elderly. After 20weeks of combined strength and endurance training, twenty-four healthy elderly men (65±4 years) were randomly placed into two frequency training groups: strength and endurance training performed twice a week (SE2, n=12); or, strength and endurance training performed three times per week (SE3, n=12). The interventions lasted 10 weeks and each group performed identical exercise intensity and volume per session. Before and after the exercise training, one maximum repetition test (1RM), isometric peak torque (PT), maximal surface electromyographic activity (EMG), as well as muscle thickness (MT) were examined. Additionally, peak oxygen uptake (VO(2peak)), maximum aerobic workload (W(max)), first and second ventilatory thresholds (VT1 and VT2) were evaluated. There were significant increases in upper and lower-body 1RM, MT, VO(2peak), VT1 and VT2, with no differences between groups. There were no changes after training in maximal EMG and isometric peak torque. W(max) was improved only in SE3. After 10 weeks of training, twice weekly combined strength and endurance training leads to similar neuromuscular and cardiovascular adaptations as three times per week, demonstrating the efficiency of lower frequency of concurrent training in previously trained elderly men. © 2013.

  8. 76 FR 30491 - National Hurricane Preparedness Week, 2011

    Science.gov (United States)

    2011-05-25

    ... information on hurricane hazards and details on how to secure buildings and belongings is available at www... coastal areas of our Nation to share information about hurricane preparedness and response to help save... Hurricane Preparedness Week, 2011 Proclamation 8680--National Safe Boating Week, 2011 Proclamation 8681...

  9. Choose Privacy Week: Educate Your Students (and Yourself) about Privacy

    Science.gov (United States)

    Adams, Helen R.

    2016-01-01

    The purpose of "Choose Privacy Week" is to encourage a national conversation to raise awareness of the growing threats to personal privacy online and in day-to-day life. The 2016 Choose Privacy Week theme is "respecting individuals' privacy," with an emphasis on minors' privacy. A plethora of issues relating to minors' privacy…

  10. The Effect of Weekly Progress Reports on Academic Achievement.

    Science.gov (United States)

    Armour, Katherine S.

    This study investigated the effect of weekly progress reports on the academic achievement of seventh grade language arts students. It also investigated the effects of weekly progress reports on locus of control attribution and the relationship between academic achievement and locus of control attribution. The study took place in a suburban school…

  11. 76 FR 63805 - National School Lunch Week, 2011

    Science.gov (United States)

    2011-10-13

    ... breakfast and lunch may consume more than half their daily calories at school. The Healthy, Hunger-Free Kids... eliminate hunger during the school day by increasing the number of eligible children enrolled in school meal... Lunch Week,'' and has requested the President to issue a proclamation in observance of this week. [[Page...

  12. 78 FR 37423 - National Small Business Week, 2013

    Science.gov (United States)

    2013-06-20

    ... Business Week, 2013 Proclamation 8995--World Elder Abuse Awareness Day, 2013 Proclamation 8996--Father's..., we have focused on making Government work better for business through initiatives like Startup... of June 14, 2013 National Small Business Week, 2013 By the President of the United States of America...

  13. Why at Least 39 Weeks Is Best for Your Baby?

    Science.gov (United States)

    ... more health problems at birth and later in life than babies born later. Being pregnant 39 weeks gives your baby's body all the time it needs to grow. Here's why your baby needs 39 weeks: Important organs, like his brain, lungs and liver, get the time they need ...

  14. 75 FR 20889 - National Crime Victims' Rights Week, 2010

    Science.gov (United States)

    2010-04-21

    ... crime and property crime, we must also fight white-collar crime and protect its victims, including those... National Crime Victims' Rights Week, 2010 By the President of the United States of America A Proclamation..., emotional, and psychological pain of past offenses. This week, we renew our commitment to supporting crime...

  15. Genetic association between sexual maturity and weekly live ...

    African Journals Online (AJOL)

    This study focused on the estimation of genetic relationships between weekly live weights and sexual maturity of male and female Japanese quail. The live body weight data of a laying-type quail line over time were collected from hatching to six weeks of age. Sexual maturity was determined as the day of production of ...

  16. 75 FR 26871 - National Women's Health Week, 2010

    Science.gov (United States)

    2010-05-12

    ... medical services, receive fair treatment, and make healthy choices. During National Women's Health Week... lives of women. Regular exercise, coupled with a nutritious diet, helps prevent heart disease, obesity... Part III The President Proclamation 8516--National Women's Health Week, 2010 Proclamation 8517...

  17. 75 FR 2049 - National Influenza Vaccination Week, 2010

    Science.gov (United States)

    2010-01-13

    ... Part IV The President Proclamation 8472--National Influenza Vaccination Week, 2010 #0; #0; #0..., 2010 National Influenza Vaccination Week, 2010 By the President of the United States of America A... hospitalization or even death. We know that influenza vaccination is the best way to protect ourselves against the...

  18. 78 FR 27032 - National Maritime Week Tugboat Races, Seattle, WA

    Science.gov (United States)

    2013-05-09

    ... Maritime Week Tugboat Races, Seattle, WA AGENCY: Coast Guard, DHS. ACTION: Notice of enforcement of... Maritime Week Tugboat Races in Elliott Bay, WA from 12 p.m. until 4:30 p.m. on May 11, 2013. This action is... these types of races which includes large wakes. During the enforcement period, no person or vessel may...

  19. 76 FR 22033 - National Maritime Week Tugboat Races, Seattle, WA

    Science.gov (United States)

    2011-04-20

    ... Maritime Week Tugboat Races, Seattle, WA AGENCY: Coast Guard, DHS. ACTION: Notice of enforcement of... Maritime Week Tugboat Races in Elliott Bay, WA from 12 p.m. through 4:30 p.m. on May 14, 2011. This action... associated with these types of races which includes large wakes. During the enforcement period, no person or...

  20. 77 FR 23120 - National Maritime Week Tugboat Races, Seattle, WA

    Science.gov (United States)

    2012-04-18

    ... Maritime Week Tugboat Races, Seattle, WA AGENCY: Coast Guard, DHS. ACTION: Notice of enforcement of... Maritime Week Tugboat Races in Elliott Bay, WA from 12 p.m. through 4:30 p.m. on May 12, 2012. This action... associated with these types of races which includes large wakes. During the enforcement period, no person or...

  1. 75 FR 24400 - National Maritime Week Tugboat Races, Seattle, WA

    Science.gov (United States)

    2010-05-05

    ... Maritime Week Tugboat Races, Seattle, WA AGENCY: Coast Guard, DHS. ACTION: Notice of enforcement of... Maritime Week Tugboat Races in Elliott Bay, WA on May 8, 2010. This action is necessary to ensure the safety of all participants and spectators from the inherent dangers associated with these types of races...

  2. Correlation and prediction equations for eight-week bodyweight in ...

    African Journals Online (AJOL)

    The 10 regression models used were: Linear; Logarithmic; Inverse; Quadratic; Cubic; Compound; Power; Sigmoidal; Growth; and Exponential equation. The results showed that Orpington breed had higher body weight than Sussex chicken for most weeks. Male chicks were generally higher in weekly body weight from 4 to 8 ...

  3. Improvement in Running Economy after 6 Weeks of Plyometric Training.

    Science.gov (United States)

    Turner, Amanda M.; Owings, Matt; Schwane, James A.

    2003-01-01

    Investigated whether a 6-week regimen of plyometric training would improve running economy. Data were collected on 18 regular but not highly trained distance runners who participated in either regular running training or plyometric training. Results indicated that 6 weeks of plyometric training improved running economy at selected speeds in this…

  4. 77 FR 65091 - National Character Counts Week, 2012

    Science.gov (United States)

    2012-10-24

    ... Vol. 77 Wednesday, No. 206 October 24, 2012 Part III The President Proclamation 8891--National Character Counts Week, 2012 Proclamation 8892--National Forest Products Week, 2012 #0; #0; #0; Presidential... involvement. We must instill in them the creativity and imagination it takes to envision a dream, and the...

  5. 76 FR 25525 - National Charter Schools Week, 2011

    Science.gov (United States)

    2011-05-05

    ... Charter Schools Week, 2011 By the President of the United States of America A Proclamation In communities across our country, successful public charter schools help put children on the path to academic... of students, parents, teachers, and administrators. During National Charter Schools Week, we...

  6. USCIS My Case Status

    Data.gov (United States)

    Department of Homeland Security — USCIS provide a way for the public who applied for U.S. citizenship to check the status of their application online. To view the status of a case, the application...

  7. Innovations, status, and networks

    NARCIS (Netherlands)

    P. Wang (Pengfei)

    2016-01-01

    markdownabstractTo obtain and maintain competitive advantage, firms need to implement appropriate innovation strategies (i.e. exploration or exploitation) and acquire status in external networks. In this dissertation, I investigate how innovation strategy, status, and network structure jointly

  8. Improved efficacy of intramuscular weekly administration of clodronate 200 mg (100 mg twice weekly) compared with 100 mg (once weekly) for increasing bone mineral density in postmenopausal osteoporosis.

    Science.gov (United States)

    Frediani, Bruno; Bertoldi, Ilaria; Pierguidi, Serena; Nicosia, Antonella; Picerno, Valentina; Filippou, Georgios; Cantarini, Luca; Galeazzi, Mauro

    2013-03-01

    Clodronate is a bisphosphonate used for the treatment of postmenopausal osteoporosis and all conditions characterized by excess bone resorption. We have previously reported that intramuscular (IM) therapy with clodronate at a dose of 100 mg/week displays significant effects on bone mineral density (BMD) although a plateau effect is observed after 1 year of treatment. Previous reports indicate that the densitometric effects of bisphosphonates directly correlate with the drug dosage and suggest that using IM clodronate at doses higher than 100 mg/week may result in improved efficacy. However, to the best of our knowledge, this has never been proved. The primary endpoint of the study was the effect on BMD of IM clodronate 100 mg once weekly or 100 mg twice weekly in patients with postmenopausal osteoporosis. The incidence of non-traumatic vertebral fractures and adverse events was also reported. The present study was a randomized, open-label, parallel-group trial conducted between January 2007 and December 2009 in the Osteoporosis and Osteoarticular Instrumental Diagnosis Centre (University of Siena, Siena, Italy). The study involved 60 women, aged 57-78 years, with a history of postmenopausal osteoporosis for more than 5 years. Patients were randomized to receive IM clodronate 100 mg once weekly (Group A, 30 patients) or 100 mg twice weekly (Group B, 30 patients), for 2 years. Significant increases compared with baseline in BMD were observed for both groups at 1 and 2 years, with significantly higher increases for Group B compared with Group A. Group B displayed a BMD increase (± SD) at the lumbar spine of +4.0 % (± 2.1) and +5.9 % (± 2.0) at 1 and 2 year(s), respectively, compared with +2.8 % (± 1.7) and +3.5 % (± 2.2), respectively, observed for Group A. Similarly, Group B showed better performance compared with Group A for BMD increase at the femoral neck, with an observed increase of +3.5 % (± 1.7) and +5.4 % (± 1.8) at 1 and 2 year(s), respectively

  9. Weekly and Twice-Weekly Yoga Classes Offer Similar Low-Back Pain Relief in Low-Income Minority Populations

    Science.gov (United States)

    ... Twice-Weekly Yoga Classes Offer Similar Low-Back Pain Relief in Low-Income Minority Populations Share: © Photodisc Results of an NCCAM-funded study found that once-weekly yoga classes relieved pain, improved function, and reduced the need for pain ...

  10. Weekly patterns of aerosol in the United States

    Directory of Open Access Journals (Sweden)

    D. M. Murphy

    2008-05-01

    Full Text Available Data from the Interagency Monitoring of Protected Visual Environments (IMPROVE network of aerosol samplers and NOAA monitoring sites are examined for weekly cycles. At remote and rural sites, fine particle elemental carbon, crustal elements, and coarse particle mass had pronounced (up to 20% weekly cycles with minima on Sunday or Monday. Fine particle organic carbon and mass had smaller amplitude cycles, also with Sunday or Monday minima. There was no statistically significant weekly cycle in fine particle sulfate despite a 5 to 15% weekly cycle in power plant SO2 emissions. Although results for nitrate may be more susceptible to sampling artifacts, nitrate also showed a pronounced weekly cycle with an amplitude similar to elemental carbon. The only species found with a weekend maximum was Pb, probably from general aviation on weekends. Aerosol optical properties at NOAA monitoring sites were consistent with the IMPROVE chemical data, with significant weekly cycles in aerosol light absorption but not light scattering. These results support a large role of diesel emissions in elemental carbon aerosol over the entire United States and suggest that a large fraction of the airborne soil dust is anthropogenic. They also suggest that studies of weekly cycles in temperature, cloudiness, precipitation, or other meteorological variables should look for causes more in light-absorbing particles and possible ice nucleation by dust rather than sulfate or total aerosol. There are also implications for personal exposure and epidemiological studies of aerosol health effects.

  11. The Impact of the Parental Support on Risk Factors in the Process of Gender Affirmation of Transgender and Gender Diverse People

    Science.gov (United States)

    Seibel, Bruna L.; de Brito Silva, Bruno; Fontanari, Anna M. V.; Catelan, Ramiro F.; Bercht, Ana M.; Stucky, Juliana L.; DeSousa, Diogo A.; Cerqueira-Santos, Elder; Nardi, Henrique C.; Koller, Silvia H.; Costa, Angelo B.

    2018-01-01

    Research involving transgender and gender diverse people (TGD) increased in the last years, mostly concerning healthcare associated to this population. Few studies dedicated their analysis to the impact of parental support on transgender people, even though this is an important aspect in creating a safe environment on which these individuals can build their identity. In addition, the link between family support, TGD identity and homelessness is not completely established. Thus, due to the specificities of the family context of TGD individuals, the aim of this study is to investigate the association between family support and TGD in different moments of the process of gender affirmation. In addition, this study also aims to explore the relationship between a lack of social support and low self-esteem, home abandonment, and dwelling in the street. The survey was designed based on the TransPULSE project and was made available in electronic format. The sample was constituted of 423 TGD residents in two Brazilian states. A Structural Equation Model analysis suggested that the impact of gender affirmation status on homelessness was mediated by parental support, through self-esteem, and the need to move from home. The association between the status of the gender affirmation procedures, family support and self-esteem was significant and indicated that the further TGD individuals advanced in gender affirmation, the more self-esteem and family support they would have. The association between family support and self-esteem indicated that family support was associated with higher self-esteem. Low family support was associated with the willingness to move from home due to one’s TGD status and there was also a significant correlation between low self-esteem and the willingness to move from home due to one’s TGD status. Finally, homelessness was associated with the willingness to move with a large effect size. Limitations include the sample that was constituted by individuals

  12. The Impact of the Parental Support on Risk Factors in the Process of Gender Affirmation of Transgender and Gender Diverse People.

    Science.gov (United States)

    Seibel, Bruna L; de Brito Silva, Bruno; Fontanari, Anna M V; Catelan, Ramiro F; Bercht, Ana M; Stucky, Juliana L; DeSousa, Diogo A; Cerqueira-Santos, Elder; Nardi, Henrique C; Koller, Silvia H; Costa, Angelo B

    2018-01-01

    Research involving transgender and gender diverse people (TGD) increased in the last years, mostly concerning healthcare associated to this population. Few studies dedicated their analysis to the impact of parental support on transgender people, even though this is an important aspect in creating a safe environment on which these individuals can build their identity. In addition, the link between family support, TGD identity and homelessness is not completely established. Thus, due to the specificities of the family context of TGD individuals, the aim of this study is to investigate the association between family support and TGD in different moments of the process of gender affirmation. In addition, this study also aims to explore the relationship between a lack of social support and low self-esteem, home abandonment, and dwelling in the street. The survey was designed based on the TransPULSE project and was made available in electronic format. The sample was constituted of 423 TGD residents in two Brazilian states. A Structural Equation Model analysis suggested that the impact of gender affirmation status on homelessness was mediated by parental support, through self-esteem, and the need to move from home. The association between the status of the gender affirmation procedures, family support and self-esteem was significant and indicated that the further TGD individuals advanced in gender affirmation, the more self-esteem and family support they would have. The association between family support and self-esteem indicated that family support was associated with higher self-esteem. Low family support was associated with the willingness to move from home due to one's TGD status and there was also a significant correlation between low self-esteem and the willingness to move from home due to one's TGD status. Finally, homelessness was associated with the willingness to move with a large effect size. Limitations include the sample that was constituted by individuals

  13. The Impact of the Parental Support on Risk Factors in the Process of Gender Affirmation of Transgender and Gender Diverse People

    Directory of Open Access Journals (Sweden)

    Bruna L. Seibel

    2018-03-01

    Full Text Available Research involving transgender and gender diverse people (TGD increased in the last years, mostly concerning healthcare associated to this population. Few studies dedicated their analysis to the impact of parental support on transgender people, even though this is an important aspect in creating a safe environment on which these individuals can build their identity. In addition, the link between family support, TGD identity and homelessness is not completely established. Thus, due to the specificities of the family context of TGD individuals, the aim of this study is to investigate the association between family support and TGD in different moments of the process of gender affirmation. In addition, this study also aims to explore the relationship between a lack of social support and low self-esteem, home abandonment, and dwelling in the street. The survey was designed based on the TransPULSE project and was made available in electronic format. The sample was constituted of 423 TGD residents in two Brazilian states. A Structural Equation Model analysis suggested that the impact of gender affirmation status on homelessness was mediated by parental support, through self-esteem, and the need to move from home. The association between the status of the gender affirmation procedures, family support and self-esteem was significant and indicated that the further TGD individuals advanced in gender affirmation, the more self-esteem and family support they would have. The association between family support and self-esteem indicated that family support was associated with higher self-esteem. Low family support was associated with the willingness to move from home due to one’s TGD status and there was also a significant correlation between low self-esteem and the willingness to move from home due to one’s TGD status. Finally, homelessness was associated with the willingness to move with a large effect size. Limitations include the sample that was

  14. Long-Acting Reversible Contraception Initiation With a 2- to 3-Week Compared With a 6-Week Postpartum Visit.

    Science.gov (United States)

    Chen, Melissa J; Hou, Melody Y; Hsia, Jennifer K; Cansino, Catherine D; Melo, Juliana; Creinin, Mitchell D

    2017-10-01

    To evaluate whether a department policy changing the scheduling of the postpartum visit from 6 weeks to 2-3 weeks after delivery is associated with higher long-acting reversible contraception initiation at the postpartum visit. We conducted a quasiexperimental before-after study to evaluate long-acting reversible contraception initiation, specifically an intrauterine device or contraceptive implant, at the postpartum visit between women scheduled for follow-up at 6 weeks (before policy change) and 2-3 weeks after delivery (after policy change). Secondary outcomes included postpartum visit completion, overall contraception initiation at the postpartum visit, overall contraceptive use at 6 months after delivery, and repeat pregnancies by 6 months postpartum. We obtained delivery and postpartum information using the electronic medical record and contacted participants 3 and 6 months after delivery to assess contraception use and repeat pregnancies. We enrolled 586 participants between December 2014 and November 2015, of whom 512 women (256 in each cohort) continued to meet eligibility criteria after delivery. Long-acting reversible contraception initiation rates at the postpartum visit were lower in the 2- to 3-week (16.5%, 95% CI 12.2-21.8) compared with the 6-week group (31.1%, 95% CI 25.2-37.7, Pcontraception initiation was higher in the 2- to 3-week group (27.3%, 95% CI 21.9-33.4) compared with the 6-week group (15.8%, 95% CI 11.5-21.4, Pcontraceptive use patterns at 6 months postpartum. No intrauterine device perforations or expulsions were observed in women who underwent insertion at 2-3 weeks postpartum. Five pregnancies were reported in each cohort by 6 months after delivery. Scheduling a visit at 2-3 weeks after delivery was not associated with increased long-acting reversible contraception initiation at this visit despite higher postpartum visit attendance.

  15. Tenofovir therapy in chronic hepatitis B infection: 48-week results from Izmir Province, Turkey

    Directory of Open Access Journals (Sweden)

    Şükran Köse

    2012-09-01

    Full Text Available Objectives: The goal of therapy in chronic hepatitis B infection (CHB is to impede liver injury by suppressing viral replication.The study was aimed to determine the efficacy of tenofovir (TDF in CHB infection for 48 weeks.Materials and methods: We retrospectively analyzed the data of 45 CHB patients treated by tenofovir. The patientswere divided into two groups based on their hepatitis B e antigen status (HBeAg. Those who were eligible to therapyreceived TDF 300 mg once daily for 48 weeks. Serum alanine aminotransferase levels (ALT, hepatitis B virus DNA (HBVDNA, and viral serological markers were checked at three-month intervals. Liver biopsy scores were determined in allpatients.Results: The mean age ± standard deviation (SD was 35.8 ± 17.0 years, 26 (57.8 % were male, and seven patients(15.5% were treatment-experienced by a nucleos(tide analogue before TDF. HBeAg was positive in 17 (37.8% patients.At week 48 among HBeAg positive (HBeAg + patients’ biochemical and virological response rates at month-3, -6 and-12 were 64.7%, and 100%, 70.6%, and 94.1%, and 88.2%, and 64.7%, respectively. The serological response in HBeAg+ patients was 29.4%. For HBeAg negative (HBeAg - patients; biochemical, and virological response rates were 64.3%,and 96.4% at month 3; 82.1%, and 96.4% at month 6; and 100%, and 85.7% at month 12, respectively. At week 48 bothgroups had significant virological response (p<0.001.Conclusion: Treatment in CHB with TDF leads to HBV DNA suppression without evident resistance for 48-week, and iswell tolerated. J Microbiol Infect Dis 2012; 2(3: 87-92Key words: Hepatitis B, chronic, tenofovir disoproxil

  16. Heuristic status polling

    Science.gov (United States)

    Archer, Charles J [Rochester, MN; Blocksome, Michael A [Rochester, MN; Heidelberger, Philip [Cortlandt Manor, NY; Kumar, Sameer [White Plains, NY; Parker, Jeffrey J [Rochester, MN; Ratterman, Joseph D [Rochester, MN

    2011-06-07

    Methods, compute nodes, and computer program products are provided for heuristic status polling of a component in a computing system. Embodiments include receiving, by a polling module from a requesting application, a status request requesting status of a component; determining, by the polling module, whether an activity history for the component satisfies heuristic polling criteria; polling, by the polling module, the component for status if the activity history for the component satisfies the heuristic polling criteria; and not polling, by the polling module, the component for status if the activity history for the component does not satisfy the heuristic criteria.

  17. Coral Reef Watch, Degree Heating Weeks, 50 km

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NOAA Coral Reef Watch distributes Degree Heating Week products using a combination of the POES AVHRR Global Area Coverage data, and data from a climatological...

  18. Factors associated with adequate weekly reporting for disease ...

    African Journals Online (AJOL)

    IDSR) strategy in 1998 to strengthen disease surveillance and epidemic response. However, the goal of weekly surveillance reporting among health facilities has not been achieved. We conducted a crosssectional study to determine the ...

  19. 75 FR 10993 - Save Your Vision Week, 2010

    Science.gov (United States)

    2010-03-10

    .... Doctors also recommend maintaining a healthy diet, not smoking, and wearing sunglasses or suitable eye protection when playing sports or performing household chores and yard work. This week, I encourage all...

  20. 78 FR 62335 - National School Lunch Week, 2013

    Science.gov (United States)

    2013-10-18

    ... sustenance they need to focus and excel. With the Healthy, Hunger-Free Kids Act, we expanded access to school... October each year as ``National School Lunch Week'' and has requested the President to issue a...

  1. 75 FR 63689 - National School Lunch Week, 2010

    Science.gov (United States)

    2010-10-15

    ... Program. This groundbreaking program has prevented hunger and promoted education by enabling our young... October each year as ``National School Lunch Week,'' and has requested the President to issue a...

  2. 78 FR 62955 - National Character Counts Week, 2013

    Science.gov (United States)

    2013-10-23

    ... examples of integrity, and moral courage, but it is our task as parents, community members, and leaders to.... This week, we reaffirm our commitment to helping our children turn away from bullying, harassment, and...

  3. Tallinn Fashion Week algas moeillustraatorite näitusega

    Index Scriptorium Estoniae

    2011-01-01

    Näitus "Uus Põhjamaade moeillustratsioon" Rotermanni kvartalis 18. sept.-ni. Osalejad Eestist, Soomest ja Rootsist loetletud. Näituse kujundaja Tuuli Aule. Väljapaneku loovjuhi Toomas Volkmanni selgitus. Tallinn Fashion Week'i põhiprogrammist

  4. Situation Update: Summary of Weekly FluView

    Science.gov (United States)

    ... respiratory specimens testing positive for influenza viruses in clinical laboratories during the week ending April 21 was 8. ... percent of specimens testing positive for influenza in clinical laboratories ranged from 2.7% to 16.9%. During ...

  5. A comparison of practice pattern and outcome of twice-weekly and thrice-weekly hemodialysis patients

    Directory of Open Access Journals (Sweden)

    T Mukherjee

    2017-01-01

    Full Text Available Renal replacement therapy (RRT options and practice varies in countries worldwide and is influenced by patients' choice, nephrologists' practice patterns, health system, payer practice, public policy, and socioeconomic factors. In India, hemodialysis (HD remains the dominant RRT modality, and the practice is largely influenced by socioeconomics of the region of practice since third party payer is limited. Resource stretch to maximize outcome benefit is essential and HD session twice weekly is an improvized and cost-effective clinical practice. However, within the country, the patient characteristics, practice patterns, and outcomes of twice-weekly HD compared against patients dialyzed thrice weekly remain unclear. We did a retrospective analysis of patients who underwent twice- and thrice-weekly HD in a single center under similar settings. The patients on thrice a week dialysis were older and with a higher proportion of diabetics and were insured by private payers. Weight gain, ultrafiltration rates, blood pressures, and hemoglobin remained more favorable in the thrice-weekly patients. There was no significant difference in the hospitalization rates or mortality rates in the two groups. Patients who undergo twice-weekly HD have poorer intermediate measures of the outcome; although, morbidity and survival were not different in a small study population with short follow-up. The small sample size and the short duration of follow-up may limit the scope of findings of our study.

  6. Concomitant weekly cisplatin and radiotherapy for head and neck cancer

    International Nuclear Information System (INIS)

    Homma, Akihiro; Inamura, Naoya; Oridate, Nobuhiko

    2011-01-01

    The most common chemoradiotherapy regimen is high-dose (100 mg/m 2 ) three-weekly cisplatin with concomitant radiotherapy; however, this protocol is associated with acute and late toxicities. Here, we reviewed the dose intensity and toxicity for concomitant weekly cisplatin and radiotherapy in patients with head and neck cancer. Fifty-three patients with untreated head and neck cancer were enrolled and evaluated at our institution from April 2006 to April 2010. Weekly cisplatin (40 mg/m 2 ) was given on weeks 1, 2, 3, 5, 6 and 7 with radiotherapy, which comprised a standard dose of 70 Gy delivered in 35 daily fractions over 7 weeks. Fifty-one patients (96.2%) received the full dose of radiotherapy, while the course was disrupted by adverse events in two. Over the course of the chemotherapy, 31 patients (58.5%) received more than 200 mg/m 2 cisplatin. The toxicity was manageable in all except one patient, who died of sepsis after completing treatment. The 2-year overall survival rate and local progression-free rate for all patients were 93.7% and 88.0%, respectively. The primary site showed a complete response in 52 patients (98.1%) and a partial response in 1 patient (1.9%). The primary disease was well controlled by chemoradiotherapy in 47 patients (88.7%). Weekly cisplatin could be easier to manage than three-weekly cisplatin, because patients can be monitored more regularly for toxicity allowing the schedule to be altered if required. This regimen appears to be a suitable alternative to three-weekly high-dose cisplatin with concomitant radiotherapy. (author)

  7. Medical image of the week: MRI of Wernicke's encephalopathy

    Directory of Open Access Journals (Sweden)

    Reyes N

    2013-02-01

    Full Text Available A 61 year old male presented to the ED with altered mental status after being found down at home with several beer cans around him. He was noted to have horizontal nystagmus on hospital day 2 and a MRI was performed. MRI showed bilateral thalamic enhancement (Figure 1, arrows on flair imaging consistent with Wernicke’s encephalopathy. His thiamine dose was increased with improvement in his mental status.

  8. An optimal decision making model for supporting week hospital management.

    Science.gov (United States)

    Conforti, Domenico; Guerriero, Francesca; Guido, Rosita; Cerinic, Marco Matucci; Conforti, Maria Letizia

    2011-03-01

    Week Hospital is an innovative inpatient health care organization and management, by which hospital stay services are planned in advance and delivered on week-time basis to elective patients. In this context, a strategic decision is the optimal clinical management of patients, and, in particular, devising efficient and effective admission and scheduling procedures, by tackling different requirements such as beds' availability, diagnostic resources, and treatment capabilities. The main aim is to maximize the patient flow, by ensuring the delivery of all clinical services during the week. In this paper, the optimal management of Week Hospital patients is considered. We have developed and validated an innovative integer programming model, based on clinical resources allocation and beds utilization. In particular, the model aims at scheduling Week Hospital patients' admission/discharge, possibly reducing the length of stay on the basis of an available timetable of clinical services. The performance of the model has been evaluated, in terms of efficiency and robustness, by considering real data coming from a Week Hospital Rheumatology Division. The experimental results have been satisfactory and demonstrate the effectiveness of the proposed approach.

  9. Offering induction of labor for 22-week premature rupture of membranes: a survey of obstetricians.

    Science.gov (United States)

    McKenzie, F; Tucker Edmonds, B

    2015-08-01

    To describe obstetricians' induction counseling practices for 22-week preterm premature rupture of membranes (PPROM) and identify provider characteristics associated with offering induction. Surveyed 295 obstetricians on their likelihood (0-10) of offering induction for periviable PPROM across 10 vignettes. Twenty-two-week vignettes were analyzed, stratified by parental resuscitation preference. Bivariate analyses identified physician characteristics associated with reported likelihood ratings. Obstetricians (N=205) were not likely to offer induction. Median ratings by preference were as follows: resuscitation 1.0, uncertain 1.0 and comfort care 3.0. Only 41% of obstetricians were likely to offer induction to patients desiring comfort care. In addition, several provider-level factors, including practice region, parenting status and years in practice, were significantly associated with offering induction. Obstetricians do not readily offer induction when counseling patients with 22-week ruptured membranes, even when patients prefer palliation. This may place women at risk for infectious complications without accruing a neonatal benefit from prolonged latency.

  10. Advanced non-small cell lung cancer in elderly patients: The standard every 3-weeks versus weekly paclitaxel with carboplatin

    Directory of Open Access Journals (Sweden)

    Hala Mohamed El-Shenshawy

    2012-10-01

    Conclusions: Efficacy was similar between the weekly regimen and the standard regimen of carboplatin and paclitaxel for elderly patients with advanced NSCLC and may be advantageous based on its favorable tolerability profile.

  11. Thirteen Week Oral Toxicity Study of WR238605 with a Thirteen Week Recovery Period in Dogs. Volume 1

    Science.gov (United States)

    1993-06-11

    Creatinine Triglycerides Creatine kinase (CK) Urea nitrogen (BUN) Urine specimens were collected in Weeks -1, 2, 4, 8 and 13, and during the recovery period...Globulin (calculated) Glucose Haptoglobin Lactate dehydrogenase (LDH) Inorganic phosphorus Potassium Sodium Page 11 ®SM tr? Contract No.: DAMD17-92...but not females in Week 2 (Tables 7.13 and 7.14). This was supported by increased levels of bilirubin in the urine of these animals and in mid dose

  12. Maternal plasma total antioxidant status in preterm labor.

    Science.gov (United States)

    Cinkaya, Aysegül; Keskin, Hüseyin Levent; Buyukkagnici, Umran; Gungor, Tayfun; Keskin, Esra Aktepe; Avsar, Ayse Filiz; Bilge, Umit

    2010-12-01

    To investigate the role of oxidative stress and antioxidant status in preterm labor. Twenty-five cases diagnosed with preterm labor were included in the study group, whereas 25 women with uncomplicated pregnancies at similar stages of pregnancy were included in the control group. Total antioxidant status was measured in maternal plasma using a Hitachi 911 auto analyzer and a total antioxidant status kit (Randox Laboratories, UK) in mmol/L. Mean serum antioxidant status were lower in patients (1.002 ± 0.177 mmol/L) than in controls (1.258 ± 0.147 mmol/L) (P labor have decreased total antioxidant status compared with uncomplicated pregnancies in similar gestational weeks. Future work should clarify whether decreased total antioxidant status precedes preterm labor in a prospective cohort study. © 2010 The Authors. Journal of Obstetrics and Gynaecology Research © 2010 Japan Society of Obstetrics and Gynecology.

  13. Rehabilitation in COPD: the long-term effect of a supervised 7-week program succeeded by a self-monitored walking program

    DEFF Research Database (Denmark)

    Ringbaek, T; Brøndum, E; Martinez, G

    2008-01-01

    rehabilitation program combined with daily self-monitored training at home on exercise tolerance and health status. Two hundred and nine consecutive COPD patients who had completed a 7-week pulmonary rehabilitation program were assessed with endurance shuttle walk test (ESWT) and the St George's Respiratory...... change in SGRQ +2.0 (p = 0.40). A relative simple and inexpensive 7-week supervised rehabilitation program combined with daily self-monitored training at home was able to maintain significant improvement in exercise tolerance and health status throughout 1 year. Death and hospital admissions due to acute...

  14. Metabolic Response to Four Weeks of Muscular Endurance Resistance Training

    Directory of Open Access Journals (Sweden)

    John W. Farrell III

    2017-10-01

    Full Text Available Background: Previous investigations have shown that muscular endurance resistance training (MERT is conducive in improving the onset of blood lactate accumulation (OBLA. However, the metabolic response and time course for adaption is still unclear. Objective: The aims of the current study were to evaluate and track the metabolic response to an individual session of MERT as well as to assess performance adaptations of supplementing an aerobic exercise training program with four weeks of MERT. Methods: Seventeen aerobically active men were randomly assigned to either the experimental (EX or control group (CON, 9 EX and 8 CON. Baseline measures included a graded exercise test (GXT and 1-repetition maximum (1RM testing for leg press (LP, leg curl (LC, and leg extension (LE. CON continued their regular aerobic activity while the EX supplemented their regular aerobic exercise with 4 weeks of MERT. Results: No significant group differences were observed for all pre-training variables. Following four weeks of training no significant differences in cardiorespiratory or metabolic variables were observed for either group. However, significant improvements in LC and LE 1-RM were observed in EX compared to CON. Substantial accumulations in blood lactate were observed following each MERT session. Conclusion: Four weeks of MERT did not improve cardiorespiratory or metabolic variables, but did significantly improve LC and LE. MERT was also observed to induce a blood lactate response similar to that of HIIT. These findings suggest greater than four weeks is need to see metabolic adaptations conducive for improved aerobic performance using MERT.

  15. Consciousness levels one week after admission to a palliative care unit improve survival prediction in advanced cancer patients.

    Science.gov (United States)

    Tsai, Jaw-Shiun; Chen, Chao-Hsien; Wu, Chih-Hsun; Chiu, Tai-Yuan; Morita, Tatsuya; Chang, Chin-Hao; Hung, Shou-Hung; Lee, Ya-Ping; Chen, Ching-Yu

    2015-02-01

    Consciousness is an important factor of survival prediction in advanced cancer patients. However, effects on survival of changes over time in consciousness in advanced cancer patients have not been fully explored. This study evaluated changes in consciousness after admission to a palliative care unit and their correlation with prognosis in terminal cancer patients. This is a prospective observational study. From a palliative care unit in Taiwan, 531 cancer patients (51.8% male) were recruited. Consciousness status was assessed at admission and one week afterwards and recorded as normal or impaired. The mean age was 65.28±13.59 years, and the average survival time was 23.41±37.69 days. Patients with normal consciousness at admission (n=317) had better survival than those with impaired consciousness at admission (n=214): (17.0 days versus 6.0 days, pconsciousness at admission had a higher percentage of survival than the impaired (78.9% versus 44.3%, pconsciousness levels: (1) normal at admission and one week afterwards, (2) impaired at admission but normal one week afterwards, (3) normal at admission but impaired one week afterwards, and (4) impaired both at admission and one week afterwards. The former two groups had significantly better survival than the latter two groups: (median survival counted from day 7 after admission), 25.5, 27.0, 7.0, and 7.0 days, respectively. Consciousness levels one week after admission should be integrated into survival prediction in advanced cancer patients.

  16. Service Level Status

    CERN Multimedia

    Lopienski, S

    2007-01-01

    Nowadays, IT departments provide, and people use, computing services of an increasingly heterogeneous nature. There is thus a growing need for a status display that groups these different services and reports status and availability in a uniform way. The Service Level Status (SLS) system addresses these needs by providing a web-based display that dynamically shows availability, basic information and statistics about various IT services, as well as the dependencies between them.

  17. [Assisted reproductive technologies and the embryo status].

    Science.gov (United States)

    Englert, Y

    The status of the human embryo has always be a subject of philosophical and theological thoughts with major social consequences, but, until the 19th century, it has been mainly an abstraction. The arrival of the human embryo in vitro, materialized by Louise Brown's birth in 1978 and above all by the supernumerary embryos produced by the Australian team of Trounson and Wood following the introduction of ovarian stimulation, will turn theoretical thoughts into a reality. Nobody may ignore the hidden intentions behind the debate, as to recognise a status to a few days old embryo will immediately have a major impact on the status of a few weeks old foetus and therefore on the abortion rights. We will see that the embryo status, essentially based as well on a vision on the good and evil as on social order, cannot be based on a scientific analysis of the reproduction process but comes from a society's choice, by essence " arbitrary " and always disputable. This does not preclude the collectivity right and legitimacy to give a precise status and it is remarkable to observe the law is careful not to specify which status to give to the human embryo. It is more thru handling procedures and functioning rules that the law designed the embryo position, neither with a status of a person, nor of a thing. It nevertheless remains true that there is a constant risk that the legislation gives the embryo a status that would call into question it's unique characteristic of early reproductive stage, jeopardizing at once the hard-won reproductive freedom (reproductive choice) as well as freedom of research on embryonic stem cells, one of the most promising field of medical research.

  18. SIS - Status Determination

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Status Determination dataset within the Species Information System (SIS) contains information related to overfishing, overfished, and approaching overfished...

  19. Improved nutritional status in elderly patients 6 months after stroke

    DEFF Research Database (Denmark)

    Brynningsen, Peter Krogh; Husted, Steen; Damsgaard, Else Marie Skjøde

    2007-01-01

    , length of stay in hospital and infectious complications. SUBJECTS AND METHODS: 89 patients with ischemic stroke consecutively admitted to a geriatric stroke rehabilitation unit had their nutritional status evaluated in the hospital at 1 week and 5 weeks after stroke, and in their own home at 3 months...... variables was 31 (35 %) at 1 week and was reduced to 20 (22 %) at 6 months. CONCLUSION: 35 % of elderly patients with ischemic stroke admitted to a geriatric rehabilitation unit were malnourished 1 week after stroke. Particularly serum proteins and body fat were affected. Follow-up of nutritional variables......INTRODUCTION: Nutritional status among stroke patients has received limited attention despite the fact, that it may have an influence on clinical outcome. Previous studies have estimated that 15-20 % of patients suffer from malnutrition in the acute phase of stroke, but so far no studies have...

  20. Vehicle Technologies' Fact of the Week 2012

    Energy Technology Data Exchange (ETDEWEB)

    Davis, Stacy Cagle [ORNL; Diegel, Susan W [ORNL; Moore, Sheila A [ORNL; Boundy, Robert Gary [ORNL

    2013-02-01

    Each week the U.S. Department of Energy s Vehicle Technology Office (VTO) posts a Fact of the Week on their website: http://www1.eere.energy.gov/vehiclesandfuels/ . These Facts provide statistical information, usually in the form of charts and tables, on vehicle sales, fuel economy, gasoline prices, and other transportation-related trends. Each Fact is a stand-alone page that includes a graph, text explaining the significance of the data, the supporting information on which the graph was based, and the source of the data. A link to the current week s Fact is available on the VTO homepage, but older Facts are archived and still available at: http://www1.eere.energy.gov/vehiclesandfuels/facts/. This report is a compilation of the Facts that were posted during calendar year 2012. The Facts were written and prepared by staff in Oak Ridge National Laboratory's Center for Transportation Analysis.

  1. Hemophagocytic syndrome secondary to tuberculosis at 24-week gestation

    Directory of Open Access Journals (Sweden)

    Alexandra Arteaga Fernández

    2017-01-01

    Full Text Available Hemophagocytic syndrome is a life-threatening disease characterized by the uncontrolled activation of macrophages, resulting in hemophagocytosis of blood cells in the bone marrow. A 20-year-old gravida at 23-week and 5-day gestation was admitted to hospital to evaluate fever up to 104°F of unknown origin, moderate cytopenia, and elevated levels of liver enzymes. Bone marrow biopsy confirmed hemophagocytic syndrome, and polymerase chain reaction came back positive for Mycobacterium tuberculosis. Supportive care and tuberculosis treatment resulted in clinical improvement. At 27 weeks and 5 days, premature rupture of the membranes occurred, and because of the high probability of reactivating the hemophagocytic syndrome, a cesarean section was performed at 29-week and 2-day gestation. Hemophagocytic syndrome is an uncommon disease which rarely appears during pregnancy. Early diagnosis and treatment can save both maternal and fetal lives.

  2. Motor cortical adaptations to 2 weeks of lower limb immobilization

    DEFF Research Database (Denmark)

    Jensen, Jesper Lundbye; Christensen, Mark Schram; Petersen, Tue Hvass

    It is well established that motor experience is associated with structural and functional plasticity within the central nervous system. It is less well investigated to which extent disuse relating to immobilization is also associated with plastic neuronal changes. The objective of this study...... was to examine the effect of 2 weeks of immobilization on corticospinal excitability using transcranial magnetic stimulation (TMS) and to investigate blood flow changes in the sensorimotor cortex during ankle movement using functional magnetic resonance imaging (fMRI). 12 healthy volunteers had the left ankle...... and foot immobilized by a cast for 2 weeks. TMS and fMRI testing was performed on 2 separate days before immobilization, on the day of cast removal and 2 weeks of recovery. fMRI was accomplished with a Siemens Trio 3T scanner and fMRI time series were obtained during both active and passive ankle movement...

  3. Short-Term Market Risks Implied by Weekly Options

    DEFF Research Database (Denmark)

    Andersen, Torben Gustav; Fusari, Nicola; Todorov, Viktor

    We study short-term market risks implied by weekly S&P 500 index options. The introduction of weekly options has dramatically shifted the maturity profile of traded options over the last five years, with a substantial proportion now having expiry within one week. Such short-dated options provide...... a direct way to study volatility and jump risks. Unlike longer-dated options, they are largely insensitive to the risk of intertemporal shifts in the economic environment. Adopting a novel semi-nonparametric approach, we uncover variation in the negative jump tail risk which is not spanned by market...... volatility and helps predict future equity returns. Incidents of tail shape shifts coincide with mispricing of standard parametric models for longer-dated options. As such, our approach allows for easy identification of periods of heightened concerns about negative tail events that are not always "signaled...

  4. [Incremental approach to hemodialysis: twice a week, or once weekly hemodialysis combined with low-protein low-phosphorus diet?].

    Science.gov (United States)

    Bolasco, Piergiorgio; Caria, Stefania; Egidi, Maria Francesca; Cupisti, Adamasco

    2015-01-01

    The start of dialysis treatment is a critical step in the care management of chronic renal failure patients. When hemodialysis is performed three times a week, rapid loss of kidney function and of urine volume output generally occur and this represents an unfavorable prognostic factor. Instead, reducing frequency of hemodialysis sessions, as well as peritoneal dialysis, can contribute to a lesser decrease of residual renal function. Unfortunately, the existing protocols for an incremental hemodialysis approach are not particularly common and they are generally limited to a twice a week hemodialysis schedule. In addition to clinical and economic reasons, an incremental approach to ESRD also contributes to better social and psychological adaptation by the patients to the dramatic change in living conditions linked to the maintenance dialysis treatment. In patients who have attitude for low-protein nutritional therapy, a once weekly dialysis schedule combined with low-protein, low-phosphorus, normal to high energy diet in the remaining six days of the week can be implemented in selected patients. In our experience, this kind of program produced important clinical results and reduction in costs and hospitalization. When compared with a three times a week dialysis schedule, a greater protection of residual renal function and of urine volume output, lower increase in 2 microglobulin, better control of phosphorus and less consumption of phosphate binders and erythropoietin were observed. Careful clinical monitoring and nutrition is essential for the safety and optimization of infrequent hemodialysis. Long-term follow-up analysis shows favorable effects on the overall survival. Furthermore, twice a week hemodialysis is not the only option for an incremental approach of dialysis commencing. In patients who have a good attitude for low-protein nutritional therapy, its arrangement with a program of once weekly dialysis represents a real and effective alternative.

  5. Bion's Agony in The Long Week-End.

    Science.gov (United States)

    Ehrlich, Robert

    2017-08-01

    In The Long Week-End Wilfred Bion focuses on his emotional distress during the first twenty-one years of his life. Rarely employing psychoanalytic terminology, he attempts to explore his emotional experience directly, struggling to find a language that could capture the complexity of inner life. Central to The Long Week-End is his desire to communicate how easily he could feel unintelligent, inept, weak, ashamed, guilty, angry, frightened, and cowardly in various settings. This self-criticism at times undermines his theoretical stance in this work, as he emphasizes the importance of doubt and uncertainty when attempting to comprehend most dimensions of experience.

  6. WEEKLY BULLETIN : WE ARE INTERESTED IN YOUR OPINION !

    CERN Multimedia

    2002-01-01

    The Weekly Bulletin publication team has prepared a questionnaire that finally allows you to say all you think, good or bad, about CERN's in-house journal. The aim of this survey is to improve the Bulletin and make it more readable and more practical. In short, we want it to be more useful to you! We will be publishing the results of this survey in a few weeks' time. Between now and then we invite you to fill out the web form, or the form just before the last page of this issue. Just 5 minutes of your time!

  7. Epo's Chronicles: A Weekly Webcomic That Teaches Space Science

    Science.gov (United States)

    Cominsky, Lynn R.; Prasad, K.; Simonnet, A.; John, K.; McLin, K.; Hill, L.

    2009-01-01

    Sonoma State University Education and Public Outreach presents Epo's Chronicles: a weekly web comic about Epo, a sentient spaceship/observatory and its humanoid companion, Alkina. Follow the adventures of Epo and Alkina as they explore the Universe and try to discover their origins. The comic employs a fictional story line incorporating both recent and classic scientific discoveries from NASA missions while educating the young and the young at heart in a creative and engaging way. Each weekly "eposode” is translated into French, Italian and Spanish, and is accompanied by supporting information including glossary entries, multi-media clips, and links to additional resources. Visit Epo's Chronicles at: http://eposchronicles.com

  8. Pregnancy week by week

    Science.gov (United States)

    ... premature birth The newborn intensive care unit (NICU) Birth defects & other health conditions Loss & grief Tools & Resources Frequently asked health questions Calculating your due date Ovulation calendar Order bereavement materials News Moms Need Blog Stories & Media ...

  9. Status of numerical relativity

    Indian Academy of Sciences (India)

    Abstract. I describe the current status of numerical relativity from my personal point of view. Here, I focus mainly on explaining the numerical implementations necessary for simulating general relativistic phenomena such as the merger of compact binaries and stellar collapse, emphasizing the well-developed current status of ...

  10. Super Refractory Status Epilepticus

    African Journals Online (AJOL)

    user

    Background: Status Epilepticus (SE) is defined as more than five minutes of persistent seizure activity without full recovery of consciousness in between the seizures. If SE fails to respond to two antiepileptic drugs, it is called refractory status epilepticus (RSE) and if it continues or recurs 24 hours after anesthesia, it is called ...

  11. Morocco: Country Status Report.

    Science.gov (United States)

    McFerren, Margaret

    A survey of the status of language usage in Morocco begins with an overview of the distribution and usage of Arabic, the official language, the Berber dialects, and French, an unofficial second language. The continuing high status and widespread use of French despite arabization efforts is discussed. A matrix follows that rates these languages and…

  12. Status of numerical relativity

    Indian Academy of Sciences (India)

    I describe the current status of numerical relativity from my personal point of view. Here, I focus mainly on explaining the numerical implementations necessary for simulating general relativistic phenomena such as the merger of compact binaries and stellar collapse, emphasizing the well-developed current status of such ...

  13. Management of preeclampsia when diagnosed between 34-37 weeks gestation: deliver now or deliberate until 37 weeks?

    Science.gov (United States)

    Owens, Michelle Y; Thigpen, Brad; Parrish, Marc R; Keiser, Sharon D; Sawardecker, Sandip; Wallace, Kedra; Martin, James N

    2014-07-01

    To evaluate maternal-newborn outcomes with immediate or expectantly managed preeclampsia first diagnosed at 34-37 weeks. Late preterm patients with preeclampsia without severe features were randomly assigned to immediate delivery (n=94) or expectant management (n = 75) until 37 weeks gestation or earlier if severe features developed. Data were analyzed by appropriate tests for continuous or categorical outcomes with differences considered significant if p managed developed severe features of preeclampsia within 72 hours versus 3% in the immediately delivered group (p preeclampsia significantly lessens her development of severe features without significantly increasing newborn risks. For the expectantly managed late preterm patient with preeclampsia, close surveillance for the first 72 hours following diagnosis and twice weekly thereafter appears prudent.

  14. Symptom burden in the last week of life

    NARCIS (Netherlands)

    Klinkenberg, Marianne; Willems, Dick L.; van der Wal, Gerrit; Deeg, Dorly J. H.

    2004-01-01

    In order to investigate symptom burden in the last week of life, we conducted after-death interviews with close relatives of deceased older persons from a population-based sample of older people in The Netherlands (n=270). Results show that fatigue, pain, and shortness of breath were common (83%,

  15. Building School Culture One Week at a Time

    Science.gov (United States)

    Zoul, Jeffrey

    2010-01-01

    Use Friday Focus memos to motivate and engage your staff every week, and help create a school culture focused on the growth of students "and" teachers. Easy to understand and implement, Friday Focus memos offer an effective and efficient way to improve student learning, staff development, and school culture from within. Written by educational…

  16. University hosts Eating Issues and Body Image Awareness Week

    OpenAIRE

    Gehrt, Katie

    2010-01-01

    The Virginia Tech Eating Disorders Task Force will host the Eating Issues and Body Image Awareness Week through Feb. 26. The event features a variety of activities to encourage participants to identify and practice healthy eating and body image attitudes. The activities are free and open to the public.

  17. 78 FR 28711 - National Women's Health Week, 2013

    Science.gov (United States)

    2013-05-15

    ... cost, including well-woman visits, domestic violence screenings and counseling, and contraceptive care... Women's Health Week, 2013 By the President of the United States of America A Proclamation Since our Nation's founding, women have given their all to expanding opportunity for their families and for future...

  18. 20 CFR 615.6 - Extended Benefits; weekly amount.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Extended Benefits; weekly amount. 615.6 Section 615.6 Employees' Benefits EMPLOYMENT AND TRAINING ADMINISTRATION, DEPARTMENT OF LABOR EXTENDED... compensation payable during such benefit year. (2) If the method in paragraph (a)(1)(iii) of this section is...

  19. Cardiovascular and autonomic response induced by a 20-week ...

    African Journals Online (AJOL)

    DOI:10.7196/SAJSM.564. Cardiovascular and autonomic response induced by a 20-week military training programme in young healthy South African males ... processed foods) and rural urbanisation in sub-Saharan Africa has seen a shift in the underlying population distribution of risk factors for cardiovascular disease.

  20. ABC's "Person of the Week": American Values in Television News.

    Science.gov (United States)

    Larson, Stephanie Greco; Bailey, Martha

    1998-01-01

    Contributes to scholarship on values and ideologies in the media by analyzing five years of ABC's "Person of the Week" segments to identify prominent types of people and values endorsed by mainstream news media. Finds that individuals most frequently selected for ABC's honor lived in the United States; worked in politics and…

  1. Effects of 16 weeks of aerobic, resistance and combination exercise ...

    African Journals Online (AJOL)

    Effects of 16 weeks of aerobic, resistance and combination exercise programmes on smoking. ... African Journal for Physical Activity and Health Sciences ... Abstract. Previous research on the cessation of smoking and the prevention of smoking recidivism using exercise training has mainly focused on aerobic training (AER).

  2. Elementary computer physics, a concentrated one-week course

    DEFF Research Database (Denmark)

    Christiansen, Gunnar Dan

    1978-01-01

    A concentrated one-week course (8 hours per day in 5 days) in elementary computer physics for students in their freshman university year is described. The aim of the course is to remove the constraints on traditional physics courses imposed by the necessity of only dealing with problems that have...

  3. 76 FR 12819 - Save Your Vision Week, 2011

    Science.gov (United States)

    2011-03-09

    ... and injuries are preventable or treatable with early detection and timely treatment, many Americans do... good eating habits, can help support a healthy and active lifestyle at any age. By seeking out... Week. During this time, I invite eye care professionals, teachers, members of the media, and all...

  4. Cervical length at 23 weeks' gestation - relation to demographic ...

    African Journals Online (AJOL)

    Multiple linear regression analysis was used to determine the variables that made a significant independent contribution towards explaining variance in cervical length. Maternal age and BMI were used as continuous variables. Results. During the study period 2 173 patients attending ultrasound clinics for a routine 23-week ...

  5. A novel artificial intelligence method for weekly dietary menu planning.

    Science.gov (United States)

    Gaál, B; Vassányi, I; Kozmann, G

    2005-01-01

    Menu planning is an important part of personalized lifestyle counseling. The paper describes the results of an automated menu generator (MenuGene) of the web-based lifestyle counseling system Cordelia that provides personalized advice to prevent cardiovascular diseases. The menu generator uses genetic algorithms to prepare weekly menus for web users. The objectives are derived from personal medical data collected via forms in Cordelia, combined with general nutritional guidelines. The weekly menu is modeled as a multilevel structure. Results show that the genetic algorithm-based method succeeds in planning dietary menus that satisfy strict numerical constraints on every nutritional level (meal, daily basis, weekly basis). The rule-based assessment proved capable of manipulating the mean occurrence of the nutritional components thus providing a method for adjusting the variety and harmony of the menu plans. By splitting the problem into well determined sub-problems, weekly menu plans that satisfy nutritional constraints and have well assorted components can be generated with the same method that is for daily and meal plan generation.

  6. Daily versus weekly iron supplementation and prevention of iron ...

    African Journals Online (AJOL)

    Objective: To demonstrate the effectiveness and social feasibility of weekly versus daily iron supplementation in preventing and treating iron deficiency anaemia among anaemic mothers. Design: A longitudinal in nature. Setting: Seven urban slum communities in Teklehaimanot Wereda, Addis Ababa, Ethiopia. Subjects: ...

  7. Use of magnesium sulfate before 32 weeks of gestation

    DEFF Research Database (Denmark)

    Wolf, H. T.; Weber, T.; Piedvache, A.

    2017-01-01

    Objectives: The use of magnesium sulfate (MgSO4) in European obstetric units is unknown. We aimed to describe reported policies and actual use of MgSO4 in women delivering before 32 weeks of gestation by indication. Methods: We used data from the European Perinatal Intensive Care in Europe (EPICE...

  8. Ruptured rudimentary horn at 22 weeks | Dhar | Nigerian Medical ...

    African Journals Online (AJOL)

    ... horn pregnancy at 22 weeks presented to Nizwa regional referral hospital in shock with features of acute abdomen. Chances of rupture in first or second trimester are increased with catastrophic haemorrhage leading to increased maternal and perinatal morbidity and mortality. Management of such cases is a challenge till ...

  9. 77 FR 31149 - National Small Business Week, 2012

    Science.gov (United States)

    2012-05-24

    ... announce the Small Business Network of the Americas and the Women's Entrepreneurship in the Americas... Small Business Week, 2012 By the President of the United States of America A Proclamation For centuries..., and we renew our promise to help their businesses grow, hire, and succeed. Because small businesses...

  10. 78 FR 30723 - National Safe Boating Week, 2013

    Science.gov (United States)

    2013-05-22

    ... oceans safe for all to enjoy. In recognition of the importance of safe boating practices, the Congress... Boating Week, 2013 By the President of the United States of America A Proclamation Every year, the United... the water should prepare by filing a float plan with family or a friend, getting a free vessel safety...

  11. 77 FR 31147 - National Safe Boating Week, 2012

    Science.gov (United States)

    2012-05-24

    ... ensure America's waterways are safe and secure for all. In recognition of the importance of safe boating... Safe Boating Week, 2012 By the President of the United States of America A Proclamation For generations... the water, boaters can minimize the risk of accident or injury by taking a boating safety course...

  12. 75 FR 29391 - National Safe Boating Week, 2010

    Science.gov (United States)

    2010-05-26

    .... In recognition of the importance of safe boating practices, the Congress, by Joint Resolution... Safe Boating Week, 2010 By the President of the United States of America A Proclamation Our Nation's... reflection. As the weather warms and people prepare to spend time on the water, let us recommit during...

  13. Prediction of Success of External Cephalic Version after 36 Weeks

    NARCIS (Netherlands)

    Kok, Marjolein; van der Steeg, Jan Willem; van der Post, Joris A. M.; Mol, Ben W. J.

    2011-01-01

    We aimed to develop a predictive model for the chance of a successful external cephalic version (ECV). We performed a prospective cohort study of women with a singleton fetus in breech presentation with a gestational age of 36 weeks or more. Data on parity, maternal age, body mass index, ethnicity,

  14. 77 FR 32877 - National Hurricane Preparedness Week, 2012

    Science.gov (United States)

    2012-06-01

    ... to share information about hurricane preparedness and response to help save lives and protect... Hurricane Preparedness Week, 2012 By the President of the United States of America A Proclamation Every year, hurricanes put communities at risk of catastrophic damage from storm surges, flooding, high winds, and...

  15. Changes in morphology and strength following an eight week ...

    African Journals Online (AJOL)

    The purpose of the current investigation was to determine the impact of eight weeks of progressive resistance exercise on strength and morphology of previously sedentary, healthy, post-menopausal women. Six women were recruited from the Grahamstown community in the Eastern Cape, South Africa. Recruits were ...

  16. Circumcision weeks: making circumcision part of routine training ...

    African Journals Online (AJOL)

    Circumcision weeks: making circumcision part of routine training and service delivery at district-level hospitals in South Africa. ... It also helps reduce herpes simplex virus type 2, a key biological co-factor thought to account for some human susceptibility to HIV infection and human papillomavirus. To address these needs ...

  17. Special Relativity in Week One: 2) All Clocks Run Slow

    Science.gov (United States)

    Huggins, Elisha

    2011-01-01

    In our initial article on teaching special relativity in the first week of an introductory physics course, we used the principle of relativity and Maxwell's theory of light to derive Einstein's second postulate (that the speed of light is the same to all observers). In this paper we study thought experiments involving a light pulse clock moving…

  18. Special Relativity in Week One: 4) Lack of Simultaneity

    Science.gov (United States)

    Huggins, Elisha

    2011-01-01

    This is our final article on teaching special relativity in the first week of an introductory physics course. One of the profound changes in our view of the world was Einstein's discovery of the lack of simultaneity. He illustrated this result with a thought experiment in which we observe a railroad car passing by us. We see the two ends of the…

  19. Special Relativity in Week One: 3) Introducing the Lorentz Contraction

    Science.gov (United States)

    Huggins, Elisha

    2011-01-01

    This is the third of four articles on teaching special relativity in the first week of an introductory physics course. With Einstein's second postulate that the speed of light is the same to all observers, we could use the light pulse clock to introduce time dilation. But we had difficulty introducing the Lorentz contraction until we saw the movie…

  20. 77 FR 16645 - National Poison Prevention Week, 2012

    Science.gov (United States)

    2012-03-21

    ... Vol. 77 Wednesday, No. 55 March 21, 2012 Part III The President Proclamation 8784--National Poison Prevention Week, 2012 Memorandum of March 16, 2012--Delegation of Reporting Functions Specified in Section... action by using medications only as directed by a health care provider and removing old or unneeded...

  1. A 13-Week Research-Based Biochemistry Laboratory Curriculum

    Science.gov (United States)

    Lefurgy, Scott T.; Mundorff, Emily C.

    2017-01-01

    Here, we present a 13-week research-based biochemistry laboratory curriculum designed to provide the students with the experience of engaging in original research while introducing foundational biochemistry laboratory techniques. The laboratory experience has been developed around the directed evolution of an enzyme chosen by the instructor, with…

  2. Four-week oral toxicity study with erythritol in rats

    NARCIS (Netherlands)

    Til, H.P.; Modderman, J.

    1996-01-01

    Erythritol was orally administered to Wistar rats at dietary levels of 0, 5, and 10% for 4 weeks. Soft stools and diarrhea were observed in male and female animals of the 10% group and in female animals of the 5% group. These symptoms disappeared during the course of the study. Mean body weights of

  3. Management of premature rupture of the membranes after 34 weeks ...

    African Journals Online (AJOL)

    Objective. To determine the optimal way to manage patients with premature rupture of the membranes after 34 weeks' gestation. Design. A prospective, randomised controlled trial comparing immediate induction and delayed induction after 24 • 48 hours. Setting. Tygerberg Hospital, Gape Town. Participants. Seventy ...

  4. Phacomatosis cesioflammea in a 5-week-old infant

    Directory of Open Access Journals (Sweden)

    Khushboo Gupta

    2016-01-01

    Full Text Available A 5-week-old male infant presented with extensive lesions of nevus flammeus and Mongolian spots affecting the face, trunk, buttocks and extremities. In addition, the child had ocular melanosis and a café-au-lait spot on the trunk. The case is being reported on account of its rarity.

  5. 78 FR 17069 - National Poison Prevention Week, 2013

    Science.gov (United States)

    2013-03-20

    ... Documents#0;#0; #0; #0;Title 3-- #0;The President ] Proclamation 8940 of March 15, 2013 National Poison..., Americans have marked National Poison Prevention Week by highlighting the steps we can take to protect... encouraging common-sense precautions and raising awareness about how to respond in a poison emergency. Thanks...

  6. Strengths use and work engagement : A weekly diary study

    NARCIS (Netherlands)

    van Woerkom, M.; Oerlemans, W.; Bakker, A.B.

    2016-01-01

    The present study among 65 civil engineers investigates the impact of organizational support for strengths use on weekly work engagement and proactive behaviour. Positive psychology postulates that strengths use makes people feel authentic and efficacious. We argue that employees use these positive

  7. The European Microwave Week 2008 and its Microwave Conferences

    NARCIS (Netherlands)

    Hoogeboom, P.; Van Vliet, F.

    2009-01-01

    Under the auspices of the European Microwave Association (EuMA) the 11th annual European Microwave Week was organized in the Amsterdam RAI Congress Centre, The Netherlands, 27-31 October 2008. This major event consisted this year of five conferences, an exhibition, and various side events. The 38th

  8. Effects of niacin supplementation (40 weeks) and two dietary levels ...

    African Journals Online (AJOL)

    Effects of niacin supplementation (40 weeks) and two dietary levels of concentrate on performance, blood and fatty acid profiles of dairy cattle. C. Rauls, U. Meyer, L. Hüther, D. von Soosten, A. Kinoshita, J. Rehage, G. Breves, S. Dänicke ...

  9. Beyond Therapy Dogs: Coordinating Large-Scale Finals Week Activities

    Science.gov (United States)

    Flynn, Holly

    2017-01-01

    Finals week activities have become increasingly popular in academic libraries in the last few years, but what is a library to do when it is not allowed to have therapy dogs? This column examines a progression of increasingly popular activities at Michigan State University Libraries. Included is an assessment of what makes them popular, our…

  10. 78 FR 57463 - National Farm Safety and Health Week, 2013

    Science.gov (United States)

    2013-09-18

    ... sectors. Their products feed, clothe, and fuel our Nation. Their way of life--handed down from generation to generation--is central to the American story. During National Farm Safety and Health Week, we... remember agricultural workers' needs in setting up health facilities and emergency response programs. As...

  11. BusinessWeek : meie valikuks on Google / Tarvo Vaarmets

    Index Scriptorium Estoniae

    Vaarmets, Tarvo

    2007-01-01

    Ajakiri BusinessWeek järjestas viimase kolme aasta tulemuste põhjal Standard & Poor's 500 indeksi koosseisu kuuluvad parimad ettevõtted. Tabel: Ettevõtete edetabel. Vt. samas: Google kroonib edetabelit; Sunoco; Colgate-Palmolive; Avon Products

  12. Experiencing Child-Led Science in Science Week

    Science.gov (United States)

    Bostrom, Carol

    2016-01-01

    In this article, Carol Bostrom shares how child-led enquiry, with children choosing their own questions to research, can work in a primary classroom. Children in three year 1 classes (ages 5-6) chose three areas of their own interest or hobby and then composed three questions for investigation for each area to be used during science week. This…

  13. Scholastic Journalism Week, February 22-28, 1998. Information Packet.

    Science.gov (United States)

    Shipp, Leslie, Comp.; Shuman, Jim, Comp.

    This packet of information presents material for journalism educators to use in celebrating Scholastic Journalism Week, February 22-28, 1998. It contains a history of journalism in outline form and in newspaper article format; 13 classroom activities; 11 special activities for outside the classroom; a sample press release; a sample editorial;…

  14. The Learning Design Studio in a 5-weeks MOOC format

    NARCIS (Netherlands)

    Garreta-Domingo, Muriel; Hernández-Leo, Davinia; Mor, Yishay; Sloep, Peter

    2018-01-01

    The present paper reports on a Massive Open Online Courses (MOOCs) for teacher professional development that uses the Learning Design Studio methodology as a pedagogical framework. It explains the training activities and supporting technologies used and discusses the findings obtained weekly from

  15. Science weekly for January 2: a preview of 2008

    CERN Multimedia

    2008-01-01

    The Science Weekly team look ahead to the scientific year of 2008. Will the LHC work? What breakthroughs will there be in the field of synthetic biology? What will happen with climate change policy? Plus, a new song by our troubadour Jonny Berliner (1/2 page)

  16. Hoogsalt moodne Tallinn Fashion Week / Jaanika Terasmaa : intervjueerinud Annely Martin

    Index Scriptorium Estoniae

    Terasmaa, Jaanika

    2010-01-01

    Tallinn Fashion Week kestab 7. novembrini. Üks moenädala korraldajaid Jaanika Terasmaa, sellest, mida moenädal pakub tavainimesele ja kui oluline on selline ettevõtmine moeloojatele, moenädala eesmärgist

  17. Maternal thyroid function at 11-13 weeks of gestation.

    Science.gov (United States)

    Ashoor, Ghalia; Kametas, Nikos A; Akolekar, Ranjit; Guisado, Julia; Nicolaides, Kypros H

    2010-01-01

    To establish normal ranges of maternal serum thyroid-stimulating hormone (TSH), free thyroxine (FT4) and free triiodothyronine (FT3) at 11-13 weeks of gestation. Maternal serum concentrations of FT3, FT4, TSH, anti-thyroperoxidase (anti-TPO) and anti-thyroglobulin (anti-Tg) antibodies were measured at 11-13 weeks. Normal ranges were constructed from the data of singleton pregnancies with no anti-thyroid antibodies resulting in live births after 34 weeks of phenotypically normal neonates with birth weight above the 5th percentile. Adjustments were made for maternal characteristics found by multiple regression analysis to affect the levels of TSH, FT3 and FT4. 3,592 of the 4,318 pregnancies examined were antibody negative, and in this group serum TSH increased whereas FT3 and FT4 decreased with gestation, and all three were lower in black than in white women. Serum FT3 and FT4 decreased but TSH did not change significantly with maternal age; TSH and FT3 increased whereas FT4 decreased with body mass index; TSH decreased whereas FT3 and FT4 increased with serum free beta-hCG. In the antibody-positive group, compared to the negative group, median TSH was higher and median FT3 and FT4 were lower. The study established normal ranges for maternal thyroid function at 11-13 weeks. Copyright 2010 S. Karger AG, Basel.

  18. 76 FR 57615 - National Health Information Technology Week, 2011

    Science.gov (United States)

    2011-09-15

    ... Health Information Technology Week, 2011 #0; #0; #0; Presidential Documents #0; #0; #0;#0;Federal... specialists as they modernize our health information systems. During National Health Information Technology... delivery of health care in the United States. Health information technology connects doctors and patients...

  19. Science Weekly for January 2: a preview of 2008

    CERN Multimedia

    2008-01-01

    Welcome to the first Science Weekly of 2008. Alok Jha and the team are on hand to gaze into their quasi-mystical balls and speculate on what will be the biggest scientific happenings over the next 12 months Ian Sample explains the intricacies of the Large Hadron Collider (LHC)

  20. 75 FR 24367 - National Charter Schools Week, 2010

    Science.gov (United States)

    2010-05-05

    ... Charter Schools Week, 2010 By the President of the United States of America A Proclamation Our Nation's future depends on the education we provide to our sons and daughters, and charter schools across America serve as laboratories for education. Ideas developed and tested by charter schools have unlocked...

  1. CTEPP NC DATA CHILD DAY CARE CENTER WEEKLY MENUS

    Science.gov (United States)

    This data set contains information on the weekly day care menus. The day care centers provided menus up to three months prior to field sampling. The Children’s Total Exposure to Persistent Pesticides and Other Persistent Pollutant (CTEPP) study was one of the largest aggregate...

  2. CTEPP-OH DATA CHILD DAY CARE CENTER WEEKLY MENUS

    Science.gov (United States)

    This data set contains information on the weekly day care menus for CTEPP-OH. The day care centers provided menus up to three months prior to field sampling. The Children’s Total Exposure to Persistent Pesticides and Other Persistent Pollutant (CTEPP) study was one of the larg...

  3. Diurnal and weekly, but no lunar rhythms in humans copulation.

    Science.gov (United States)

    Palmer, J D; Udry, J R; Morris, N M

    1982-02-01

    A study was conducted to determine the solar day, lunar day, and weekly rhythms in human copulatory behavior. The study subjects were young married couples, with a median age of 25, living in North Carolina. All avoided conception by means other than oral contraception (OC). The husband and wife were paid $1.00/day for completing a questionnaire each morning, reporting whether they had engaged in intercourse in the previous 24 hours. Subjects recorded copulatory events to the nearest hour. Discrepancies between report pairs on whether intercourse had occurred were less than 1%. The data presented are from 2 studies, 1 consisting of 48 couples, reporting 1230 copulations between September 3 and December 2, 1973, and the other of 30 couples, over 711 copulations recorded between June 8 and September 5, 1974. Only the women's responses are reported here; menses were ignored. The average copulation rate/couple was 2.48 times/week in the 1973 study and 2.34 times/week for the 1974 group. The extreme values were 7.4 times/week and 0.64 times/week. Combining all the data produced a mean rate of 2.44 copulations/week. Mean daily copulatory rates for both studies were so similar that the data were pooled into a single curve for presentation. The copulation rates on weekdays were very similar, with just under 1/3 of the sample copulating each day. The average daily rates increased to 40.3% on Saturdays and to 52.6% on Sundays. The rate on Friday differed significantly from Saturday and Saturday from Sunday. 38.3% of the week's copulations occurred on the weekend. On 10.6% of the days that couples copulated, they did so twice or (rarely) 3 times, in a single day. Single-couple multiple copulations were 3.4 times more common on Sundays than on a weekday and 1.6 times more common than on Saturdays. 61% in 1973 and 66% in 1974 of all weekday copulations took place between the hours of 10:00 p.m. and 1:00 a.m. For the weekend it was mainly the augmented copulation rates during

  4. Weekly cycle of minor air gases in Moscow

    Science.gov (United States)

    Lokoshchenko, Mikhail A.; Elansky, Nikolay F.; Trifanova, Alexandra V.

    2017-04-01

    The weekly cycle of the surface concentrations of five trace atmospheric gases in Moscow has been analyzed based on continuous automatic once-a-minute measurements. The data of joint ecological station of the Institute of Atmospheric Physics and Moscow State University for nine years (2002-2010) were used. This station operated in conditions of comparatively clear park zone of the University on the South-Western periphery of the city at a distance of 8 km from the city centre. Fortunately, none of the great sources of the air pollution - neither point sources, nor linear ones - are present in the vicinity of the station so that the measurements there are quite representative. Results of spectral analysis demonstrate statistically significant maximum of spectral density close to 7 days. Any clear periodicity of around seven days may be a consequence of either natural synoptic period or weekly cycle. The fact that the influence of human activity on urban air composition changes with a weekly periodicity is confirmed by statistically significant difference between concentrations of trace gases on working days and on Sunday (when emissions from both the traffic and the industrial sources are minimal). On average, both primary pollutants (nitrogen oxide and carbon oxide) and the secondary ones (NO2) show the lowest concentrations of the week on Sunday whereas ozone, by contrast, peaks on this day. Besides, usual diurnal cycle of air pollutants is transformed on Sunday - e.g., secondary nocturnal maximum of ozone in the city is absent on Sunday like at rural area. On Saturday concentrations of trace gases are in between working days and Sunday; this 'Saturday effect' is a result of a gradual clearing of the urban air. An additional effect is that in the first half of Monday (before noon) surface concentrations of NO and NO2 are generally less, whereas the concentration of O3 is, on the contrary, a bit higher than at the same time on the rest of working days. The 'Monday

  5. Do associations between objectively-assessed physical activity and neighbourhood environment attributes vary by time of the day and day of the week?

    DEFF Research Database (Denmark)

    Cerin, Ester; Mitáš, Josef; Cain, Kelli L

    2017-01-01

    such associations varied by employment status, gender and city. METHODS: This cross-sectional study included 6,712 adults from 14 cities across 10 countries with ≥1 day of valid accelerometer-assessed MVPA and complete information on socio-demographic and objectively-assessed environmental characteristics within 0...... of week, gender and employment status were significant moderators of environment-MVPA associations. Land use mix was positively associated with MVPA in women who were employed and in men irrespective of their employment status. The positive associations between MVPA and net residential density...... of daily life centres (e.g., workplaces) to explaining adults' PA at specific times of the day....

  6. Medical image of the week: acute encephalopathy in a multiple myeloma patient

    Directory of Open Access Journals (Sweden)

    Ateeli H

    2018-02-01

    Full Text Available No abstract available. A 45-year-old man with new diagnosis of multiple myeloma waiting to start treatment presented with worsening dizziness, blurred vision that progressed to altered mental status over a week. His physical exam revealed confusion but no focal deficit. His extensive work up showed no abnormality except for mildly elevated serum viscosity. The patient was started immediately on plasmapheresis. He also received dexamethasone, thalidomide and cyclophosphamide. His symptoms resolved completely within a few days of therapy. Serum viscosity measurements do not correlate well with symptoms or the clinical findings of hypervicosity syndrome. Plasmapheresis promptly relieves the symptoms and should be performed in symptomatic patients regardless of the viscosity level (1,2.

  7. Breastfeeding, infant formula, and introduction to complementary foods - comparing data obtained by questionnaires and health visitors' reports to weekly short message service text messages

    DEFF Research Database (Denmark)

    Bruun, Signe; Buhl, Susanne; Husby, Steffen

    2017-01-01

    of the present analysis was to compare data on infant nutrition, that is, breastfeeding, use of infant formula, and introduction to complementary foods, obtained by four different methods. We assumed that weekly short message service (SMS) questions were the most reliable method, to which the other methods were...... weeks, and the mean age when introduced to complementary foods from 19 to 21 weeks. The mean duration of any breastfeeding was 33 weeks across methods. CONCLUSIONS: Compared with the weekly SMS questions, the self-administered questionnaires and the health visitors' reports resulted in a greater...... proportion of mothers with an unknown breastfeeding status, a longer duration of exclusive breastfeeding and later introduction to complementary foods, while the duration of any breastfeeding did not differ....

  8. Thirteen Week Oral Toxicity Study of WR238605 with a Thirteen Week Recovery Period in Dogs. Volume 3

    Science.gov (United States)

    1993-06-11

    Neshesheim, (Boca Raton : CRC Press, 1982), Volume I, pp. 219-246. 3 J.A.D. Cooper, Jr., D.A. White, and R.A. Matthay, "Drug Induced Pulmonary Disease, Part...after a thirteen week recovery period. This wi 11 be accomp 1 i shed by sod i urn pentobarbital anesthesia and exsanguination. An extensive

  9. SU-D-BRD-02: Auto Weekly - An Automated Online Weekly Chart Check System for Medical Physics

    International Nuclear Information System (INIS)

    Tan, J; Yan, Y; Hager, F; Gu, X; Jia, X; Pompos, A; Foster, R; Stojadinovic, S; Yang, M; Hrycushko, B; Folkerts, M; Zhao, B; Medin, P; Ding, C; Jiang, S

    2015-01-01

    Purpose: Radiation therapy has evolved to become not only more precise and potent, but also more complicated to monitor and deliver. More rigorous and comprehensive quality assurance is needed to safeguard ever advancing radiation therapy. ICRU standards dictate that an ever growing set of treatment parameters are manually checked weekly by medical physicists. This “weekly chart check” procedure is laborious and subject to human errors or other factors. A computer-assisted chart checking process will enable more complete and accurate human review of critical parameters, reduce the risk of medical errors, and improve the efficiency. Methods: We developed a web-based software system that enables a thorough weekly quality assurance checks. In the backend, the software retrieves all machine parameters from a Treatment Management System (TMS) and compares them against the corresponding ones from the treatment planning system. They are also checked for validity against preset rules. The results are displayed as a web page in the front-end for physicists to review. Then a summary report is generated and uploaded automatically to the TMS as a record for weekly chart checking. Results: The software system has been deployed on a web server in our department’s intranet, and has been tested thoroughly by our clinical physicists. A plan parameter would be highlighted when it is off the preset limit. The developed system has changed the way of checking charts with significantly improved accuracy, efficiency, and completeness. It has been shown to be robust, fast, and easy to use. Conclusion: A computer-assisted system has been developed for efficient, accurate, and comprehensive weekly chart checking. The system has been extensively validated and is being implemented for routine clinical use

  10. SU-D-BRD-02: Auto Weekly - An Automated Online Weekly Chart Check System for Medical Physics

    Energy Technology Data Exchange (ETDEWEB)

    Tan, J; Yan, Y; Hager, F; Gu, X; Jia, X; Pompos, A; Foster, R; Stojadinovic, S; Yang, M; Hrycushko, B; Folkerts, M; Zhao, B; Medin, P; Ding, C; Jiang, S [UT Southwestern Medical Center, Dallas, TX (United States)

    2015-06-15

    Purpose: Radiation therapy has evolved to become not only more precise and potent, but also more complicated to monitor and deliver. More rigorous and comprehensive quality assurance is needed to safeguard ever advancing radiation therapy. ICRU standards dictate that an ever growing set of treatment parameters are manually checked weekly by medical physicists. This “weekly chart check” procedure is laborious and subject to human errors or other factors. A computer-assisted chart checking process will enable more complete and accurate human review of critical parameters, reduce the risk of medical errors, and improve the efficiency. Methods: We developed a web-based software system that enables a thorough weekly quality assurance checks. In the backend, the software retrieves all machine parameters from a Treatment Management System (TMS) and compares them against the corresponding ones from the treatment planning system. They are also checked for validity against preset rules. The results are displayed as a web page in the front-end for physicists to review. Then a summary report is generated and uploaded automatically to the TMS as a record for weekly chart checking. Results: The software system has been deployed on a web server in our department’s intranet, and has been tested thoroughly by our clinical physicists. A plan parameter would be highlighted when it is off the preset limit. The developed system has changed the way of checking charts with significantly improved accuracy, efficiency, and completeness. It has been shown to be robust, fast, and easy to use. Conclusion: A computer-assisted system has been developed for efficient, accurate, and comprehensive weekly chart checking. The system has been extensively validated and is being implemented for routine clinical use.

  11. Effects of iron supplementation twice a week on attention score and haematologic measures in female high school students.

    Science.gov (United States)

    Rezaeian, Akram; Ghayour-Mobarhan, Majid; Mazloum, Seyed Reza; Yavari, Mehri; Jafari, Seyed-Ali

    2014-11-01

    Iron deficiency, associated with a decline in cognitive function, is the most common nutritional deficiency globally. The present study aimed to identify the impact of weekly iron supplements on the attention function of female students from a high school in North Khorasan Province, Iran. This was a blind, controlled, clinical trial study, involving 200 female students who were chosen using the stratified randomised sampling method. First, laboratory studies were performed to detect iron consumption limitations. Next, the 200 students were divided randomly and equally into case and control groups. The case group was treated with 50 mg of ferrous sulfate twice a week for 16 weeks. We compared both groups' data on attention, iron status and erythrocyte indices. Questionnaires were used to collect demographic data, while clinical data was collected using complete blood count and Toulouse-Piéron tests. Data was analysed using descriptive statistics, as well as paired and independent t-tests. The mean attention scores of the case and control groups were 104.8 ± 7.0 and 52.7 ± 9.6, respectively (p attention scores and haemoglobin concentrations of the case group were found to be improved by approximately 90% and 10%, respectively. Oral iron supplements (50 mg twice a week for 16 weeks) were able to improve the attention span and haematologic indices of female high school students.

  12. Conservative Management of an Advanced Abdominal Pregnancy at 22 Weeks

    Science.gov (United States)

    Marcellin, Louis; Ménard, Sophie; Lamau, Marie-Charlotte; Mignon, Alexandre; Aubelle, Marie Stephanie; Grangé, Gilles; Goffinet, François

    2014-01-01

    Objective We report an uneventful conservative approach of an advanced abdominal pregnancy discovered at 22 weeks of gestation. Study Design This study is a case report. Results Attempting to extend gestation of an advanced abdominal pregnancy is not a common strategy and is widely questioned. According to the couple's request, the management consisted in continuous hospitalization, regular ultrasound scan, and antenatal corticosteroids. While the woman remained asymptomatic, surgery was planned at 32 weeks, leading to the birth of a preterm child without any long-term complications. Placenta was left in situ with a prophylactic embolization, and its resorption was monitored. Conclusion Depending on multidisciplinary cares and agreement of the parents, when late discovered, prolonging advanced abdominal pregnancy appears to be a reasonable option. PMID:25032062

  13. Medical image of the week: superior vena cava syndrome

    Directory of Open Access Journals (Sweden)

    Ateeli H

    2016-08-01

    Full Text Available Superior vena cava (SVC syndrome results from obstruction of blood flow in the SVC. Most cases are secondary to malignancy, the most common being lung cancer or non-Hodgkin lymphoma. Other less encountered etiologies include fibrosing mediastinitis and thrombosis associated with intravascular devices (1,2. Here, we present a case of advanced lung cancer undergoing chemo-radiation therapy who presented with typical symptoms of SVC syndrome including progressive shortness of breath and facial swelling/ fullness over weeks to months. His chest CT scan showed SVC obstruction due to his tumor mass (Figure 1. The patient underwent stenting and improved partially for sometime. However, he returned again with worsening symptoms over a few weeks with discovery of SVC in-stent thrombosis. He was started on therapeutic enoxaparin and his symptoms improved partially with time.

  14. The construction of the other in a Brazilian weekly magazine

    Directory of Open Access Journals (Sweden)

    José Luiz Aidar Prado

    2005-12-01

    Full Text Available Postmodern thought considers, in general, otherness as absolute. Bernstein (1991 denies such absoluteness, as there is always a possibility of failure in doing justice to the otherness; we should assume the responsibility of acknowledging the otherness of the Other. In this article I propose to examine the possibility of regarding the relationship between the reader and the media as ethical, that is, respecting otherness. To do so, we counterbalance the bernsteinian view with other stances, confronting communitarian authors and non-communitarian ones. What would be the meaning of the Reader’s unfaithfulness in terms of a reading and communication contract? We intend to answer such questions on the basis of a thematic and discursive examination of the Brazilian weekly magazine Veja (approximately one million issues weekly, particularly analyzing how otherness is constructed in the cover stories dealing with topics such as violence and punishment, wealth and poverty.

  15. Vehicle Technologies' Fact of the Week 2011

    Energy Technology Data Exchange (ETDEWEB)

    Davis, Stacy Cagle [ORNL; Diegel, Susan W [ORNL; Boundy, Robert Gary [ORNL

    2012-04-01

    Each week the U.S. Department of Energy s Vehicle Technology Program (VTP) posts a Fact of the Week on their website: http://www1.eere.energy.gov/vehiclesandfuels/. These Facts provide statistical information, usually in the form of charts and tables, on vehicle sales, fuel economy, gasoline prices, and other transportation-related trends. Each Fact is a stand-alone page that includes a graph, text explaining the significance of the data, the supporting information on which the graph was based, and the source of the data. A link to the current Fact is available Monday through Friday on the VTP homepage, but older Facts are archived and still available at: http://www1.eere.energy.gov/vehiclesandfuels/facts/. This report is a compilation of the Facts that were posted during calendar year 2011. The Facts were written and prepared by staff in Oak Ridge National Laboratory's Center for Transportation Analysis.

  16. Temporal effects of maternal and pregnancy characteristics on serum PAPP-A and free β-hCG at 7-14 weeks' gestation

    DEFF Research Database (Denmark)

    Ball, Susan; Ekelund, Charlotte; Wright, Dave

    2013-01-01

    Objective: Investigate gestational age dependent effects of racial origin, smoking status and mode of conception on maternal serum levels of free ß-human chorionic gonadotropin (β-hCG) and pregnancy associated plasma protein-A (PAPP-A) at 7-14 weeks' gestation. Methods: Data arise from prospective...

  17. The marine biological week as an approach to science

    Science.gov (United States)

    Ransdorf, Angela; Satzinger, Viktoria

    2017-04-01

    The "Wiedner Gymnasium" is an academic high school with two branches: one focusses on languages and the other one on science. In the language branch the students learn at least three languages; one of which is Latin, whereas the students of the scientific branch can learn geometrical drawing and have to attend a scientific laboratory throughout the last four upper classes. As incentive highlights the language classes have a one week's school trip to France, Italy or Spain at the beginning of their 7th form in order to attend a language school and to practice their language skills. As a counterbalance, there was introduced the "marine biological week" several years ago, in which the students of the scientific branch take part whilst their colleagues have their language trips. The marine biological week takes place in Rovinj, Croatia. A team of biologists and divers leads through a programme, by which the students get an overview of different habitats, their conditions and the different ways of adaptation organisms find. Thus, they also become acquainted with several species of animals and plants which are characteristic for this area. They become familiar with some methods of scientific work and also get to know some of the problems marine ecosystems are confronted with. They also learn a little bit if the Mediterranean history and culture. Back in school all the findings are reviewed and brought into an ecological context. The insights can be used for many other topics, too, such as e.g. evolution. This week has proved to be a good start as well for the topic of ecology as for learning to think scientifically in general. So, you can call it a pivot for the scientific branch of our school.

  18. A thirteen week ad libitum administration toxicity study of tartrazine ...

    African Journals Online (AJOL)

    Tartrazine is a colorant widely used in food products, drugs and cosmetics. The current study evaluates the effect of sub-chronic ingestion of tartrazine in drinking water at doses of 0, 0.1, 0.45, 1 and 2.5% for 13 weeks in mice. Our results show that female body weight gain and food consumption decreased in all treated ...

  19. Sonographic features of lethal multiple pterygium syndrome at 14 weeks.

    Science.gov (United States)

    Chen, Min; Chan, Gavin Shueng Wai; Lee, Chin Peng; Tang, Mary Hoi Yin

    2005-06-01

    Lethal multiple pterygium syndrome is a rare inherited disorder. Previous reports suggest that the diagnosis may be based on prenatal sonographic demonstration of severe limb flexion, absence of fetal motion, and a large cystic hygroma in the second and third trimesters. We present the sonographic features and postmortem features of a fetus with lethal multiple pterygium syndrome at 13 weeks of gestation, which shows that the condition can possibly be diagnosed in the first trimester of pregnancy.

  20. Six-week retention after postplacental copper intrauterine device placement.

    Science.gov (United States)

    Colwill, Alyssa Covelli; Schreiber, Courtney A; Sammel, Mary D; Sonalkar, Sarita

    2018-03-01

    We sought to evaluate the 6-week clinical outcomes (intrauterine device [IUD] retention, recognized expulsions, ability to visualize or palpate strings, and need for ultrasound evaluation) in women who received a TCu380A postplacental IUD (PPIUD) after vaginal (VD) or cesarean delivery (CD). We conducted a retrospective cohort study to examine the 6-week retention of TCu380A IUDs placed within 10 min of placental delivery in VD (n=137) and CD (n=73). We used Student's t test and Wilcoxon rank sum tests for continuous data and Pearson χ 2 test and Fisher's Exact Test for categorical data. Of the 169 women who had follow-up, 151 (89.3%) retained their IUD at 6 weeks (95% CI 84.7%-93.9%). All women who underwent CD retained their IUD at 6 weeks postpartum (56/56), whereas 95/113 (84% [95% CI 76.0%-90.3%]) who underwent VD retained their original IUD (p<.01). Strings were detected more frequently in women who had a VD (93.1% [95% CI 85.6-97.4]) compared to those who delivered by CD (44.2% [95% CI 30.5-58.7]; p<.01). Women who underwent CD had an ultrasound to evaluate IUD location more frequently (42.9% [95% CI 29.7-56.8]) compared to women who underwent VD (13.7% [95% CI 7.5-22.3]; p<.01). Women are more likely to retain a PPIUD after CD compared to a VD (p<.01); however, women who have a PPIUD placed after CD are more likely to have nonvisible strings with a pelvic exam (p<.01) and undergo pelvic ultrasound evaluation (p<.01) compared to a PPIUD placed at the time of a VD. Copyright © 2017 Elsevier Inc. All rights reserved.

  1. Medical image of the week: tooth impaction and extraction

    Directory of Open Access Journals (Sweden)

    Afaq T

    2012-12-01

    Full Text Available A 66-year-old gentleman with a history Friedreich’s ataxia underwent a dental extraction procedure just prior to 4 weeks of traveling abroad. He was seen in emergency room for increasing weakness, cough and low grade fevers. His chest x-ray revealed a foreign body in the right main bronchus (Figure 1. He underwent bronchoscopy with forceps and basket removal of partially impacted teeth from the bronchus intermedius (Figure 2.

  2. Postdocs Attend Special Events during Postdoc Appreciation Week | Poster

    Science.gov (United States)

    NCI at Frederick postdocs were treated to special events by the Fellows and Young Investigators Committee during National Postdoc Appreciation Week, September 15–19. At the first Frederick fellows seminar of the fall on September 17, postdocs were invited to hear their colleagues present highlights of their research and stay for pizza and ice cream, compliments of the committee. Postdocs are also invited to a special networking event at Barley and Hops on September 24.

  3. STATUS GIZI DAN STATUS KESEHATAN SUKU BADUY

    Directory of Open Access Journals (Sweden)

    Faisal Anwar

    2012-03-01

    Full Text Available 800x600 Normal 0 false false false IN X-NONE X-NONE /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:10.0pt; font-family:"Calibri","sans-serif"; mso-bidi-font-family:"Times New Roman";} The objectives of the study were: (1 To analyze the socio-economic and demographic characteristics of Baduy people; (2 To analyze the health status and nutritional status of Baduy people and its influential factors. This research is an explorative and descriptive study on the socio-cultural aspects of food system. The data were collected through a direct interview and discussion with respondents as well as a direct observation at the location of respondents. A sample size of 338 households was drawn from the population. To obtain the data on the cultural aspects, history and  socio aspect of food, in-depth interviews was conducted with 19 key persons. The study was last for 12 months. In Outer Baduy, the factors significantly related to nutritional status are age, number of household size, income, nutritional knowledge, and wife’s ability to read. In Moslem Baduy, only age and income are related to the nutritional status of children. In Moslem Baduy and the Outer Baduy, the correlation between age and W/A or W/H is similar: namely, the higher the age, the lower would the Z-score for the W/A or W/H. The income is significantly correlated to the child nutritional status according to Z-score for W/A with a high correlation coefficient, that is, 0.61. This means that the higher the income, the higher would be the Z-score value for the W/A.  The distribution of adults according to BMI classification in Outer Baduy it shows that 12.7% husbands and 17.6% wives are thin (wasted, while the

  4. Winter fuels report, week ending October 5, 1990

    Energy Technology Data Exchange (ETDEWEB)

    1990-10-11

    The Winter Fuels Report is intended to provide concise, timely information to the industry, the press, policymakers, consumers, analysts, and state and local governments on the following topics: distillate fuel oil net production, imports and stocks for all PADD's and product supplied on a US level; propane net production, imports and stocks for Petroleum Administration for Defense Districts (PADD) I, II, and III; natural gas supply and disposition and underground storage, for the United States and consumption for all PADD's; residential and wholesale pricing data for propane and heating oil for those states participating in the joint Energy Information Administration (EIA)/State Heating Oil and Propane Program; crude oil and petroleum price comparisons for the United States and selected cities; and US total heating degree-days by city. This report will be published weekly by the EIA starting the first week in October 1990 and will continue until the first week in April 1991. The data will also be electronically after 5:00 p.m. on Thursday during the heating season through the EIA Electronic Publication System (EPUB). See page ii for details. 12 tabs.

  5. Winter fuels report, week ending December 21, 1990. [Contains glossary

    Energy Technology Data Exchange (ETDEWEB)

    1990-12-28

    The Winter Fuels Report is intended to provide concise, timely information to the industry, the press, policymakers, consumers, analysts, and State and local governments on the following topics: distillate fuel oil net production, imports and stocks for all PADD's and product supplied on a US level; propane net production, imports and stocks for Petroleum Administration for Defense Districts (PADD), I, II, and III; natural gas supply and disposition and underground storage for the United States and consumption for all PADD's; residential and wholesale pricing data for propane and heating oil for those States participating in the joint Energy Information Administration (EIA)/State Heating Oil and Propane Program; crude oil and petroleum price comparisons for the United States and selected cities; and US total heating degree-days by city. This report will be published weekly by the EIA starting the first week in October 1990 and will continue until the first week in April 1991. The data will also be available electronically after 5:00 p.m. on Thursday during the heating season through the EIA Electronic Publication System (EPUB). 34 figs., 12 tabs.

  6. Winter fuels report, week ending December 7, 1990. [Contains glossary

    Energy Technology Data Exchange (ETDEWEB)

    1990-12-13

    The Winter Fuels Report is intended to provide concise, timely information to the industry, the press, policymakers, consumers, analysts, and state and local governments on the following topics: distillate fuel oil net production, imports and stocks for all PADD's and product supplied on a US level; propane net production, imports and stocks for Petroleum Administration for Defense Districts (PADD) I, II, and III; natural gas supply and disposition and underground storage for the United States and consumption for all PADD's; residential and wholesale pricing data for propane and heating oil for those states participating in the joint Energy Information Administration (EIA)/State Heating Oil and Propane Program; crude oil and petroleum price comparisons for the United States and selected cities; and US total heating degree-days by city. This report will be published weekly by the EIA starting the first week in October 1990 and will continue until the first week in April 1991. 27 figs., 12 tabs.

  7. Maternal serum placental growth factor in prospective screening for aneuploidies at 8-13 weeks' gestation.

    Science.gov (United States)

    Pandya, Pranav; Wright, David; Syngelaki, Argyro; Akolekar, Ranjit; Nicolaides, Kypros H

    2012-01-01

    To investigate whether measurement of maternal serum placental growth factor (PLGF) can improve the performance of first-trimester combined screening for trisomy-21 by fetal nuchal translucency (NT) thickness and serum free β-human chorionic gonadotropin (β-hCG) and PAPP-A. In singleton pregnancies attending for routine care, serum PLGF, free β-hCG and PAPP-A were measured at 8(+0)-13(+6) weeks' gestation, and fetal NT was measured at 11(+0)-13(+6) weeks. The population included 12,154 normal and 44 trisomy-21 pregnancies. We examined the effect of adding PLGF on the performance of screening by the combined test. In the trisomy-21 pregnancies the median multiple of the normal median PLGF, adjusted for gestational age, maternal weight, racial origin, smoking status and method of conception, was significantly reduced (0.6070, 95% CI 0.5543-0.6648), and this did not change significantly with gestational age. Adding PLGF to combined testing with a risk cut-off of 1 in 100 reduced the false positive rate from 2.7% (95% CI 2.5-3.0) to 2.6% (95% CI 2.4-2.8) and increased the detection rate from 85% (95% CI 75-93) to 88% (95% CI 78-95). Inclusion of serum PLGF improves the performance of the first-trimester combined test in screening for trisomy-21. Copyright © 2012 S. Karger AG, Basel.

  8. Semantic Web status model

    CSIR Research Space (South Africa)

    Gerber, AJ

    2006-06-01

    Full Text Available by researchers and practitioners, spanning a vast landscape of different fields, technologies, concepts and application areas. Furthermore, there is confusion with regards to the current status of the enabling technologies envisioned to realise the Semantic Web...

  9. NAIP Status Maps Gallery

    Data.gov (United States)

    Farm Service Agency, Department of Agriculture — NAIP Status Maps Gallery. These maps illustrate what aerial imagery collection is planned, whats been collected, when it is available and how it is available. These...

  10. Micronutrient status in phenylketonuria

    NARCIS (Netherlands)

    Robert, M.; Rocha, J. C.; van Rijn, M.; Ahring, K.; Belanger-Quintana, A.; MacDonald, A.; Dokoupil, K.; Ozel, H. Gokmen; Lammardo, A. M.; Goyens, P.; Feillet, F.

    2013-01-01

    Patients with phenylketonuria (PKU) encompass an 'at risk' group for micronutrient imbalances. Optimal nutrient status is challenging particularly when a substantial proportion of nutrient intake is from non-natural sources. In PKU patients following dietary treatment supplementation with

  11. PRESENT STATUS IN INDIA

    Indian Academy of Sciences (India)

    First page Back Continue Last page Overview Graphics. PRESENT STATUS IN INDIA. FIXED LINES – 36 MILLION. MOBILE CONNECTIONS – 14 MILLION. TELEDENSITY APPROXIMATELY 5. INTERNET CONNECTIONS – 5 MILLION. INTERNET USERS NEARLY – 25 MILLION.

  12. ANAIS status report

    Energy Technology Data Exchange (ETDEWEB)

    Amare, J; Borjabad, S; Cebrian, S; Cuesta, C; Fortuno, D; Garcia, E; Gomez, H; Morales, J; Ortigoza, Y; Ortiz de Solorzano, A; Pobes, C; Puimedon, J; Rodriguez, A; Sarsa, M L; Villar, J A, E-mail: cpobes@unizar.e [University of Zaragoza. C/Pedro Cerbuna 12, 50009. Zaragoza (Spain)

    2010-01-01

    We report the status of the ANAIS (Annual modulation with NAI Scintillators) experiment focusing on the developments towards the improvement of the background level of our detectors and the reduction of the energy threshold.

  13. Treatment with exenatide once weekly or twice daily for 30 weeks is associated with changes in several cardiovascular risk markers

    Directory of Open Access Journals (Sweden)

    Chiquette E

    2012-11-01

    Full Text Available Elaine Chiquette,1 Peter P Toth,2 Gilbert Ramirez,3 Michael Cobble,4 Robert Chilton51Amylin Pharmaceuticals, San Diego, CA, 2University of Illinois, Peoria, IL, 3Florida International University, Miami, FL, 4Atherotech, Birmingham, AL, 5University of Texas, San Antonio, TX, USABackground: Dyslipidemia and type 2 diabetes are two of the most significant risk factors for the development of cardiovascular disease. Measurement of lipoprotein subclasses provides important information about derangements in lipid metabolism and helps refine cardiovascular risk assessment. Exenatide, a glucagon-like peptide 1 receptor agonist, improved glycemic control, obesity, hypertension, and dyslipidemia in patients with type 2 diabetes in clinical trials.Methods: In the DURATION-1 trial, patients with type 2 diabetes were treated with exenatide once weekly or twice daily for 30 weeks. This post hoc analysis evaluated the impact of exenatide on lipoprotein subclasses in 211 DURATION-1 patients using vertical auto profile methodology and the Statistical Package for the Social Sciences general linear model adjusted for glycosylated hemoglobin (HbA1c and weight.Results: Baseline lipids and high sensitivity C-reactive protein were normal overall based on the standard lipid panel. Once-weekly exenatide reduced apolipoprotein B and the apolipoprotein B to apolipoprotein A1 ratio (P < 0.05, independent of glycemic improvement and weight loss. A significant shift in lipoprotein pattern away from small, dense low-density lipoprotein-4 cholesterol was also observed (P < 0.05. Exenatide once weekly increased high-density lipoprotein-2 cholesterol, even after adjustment for changes in HbA1c and weight (P < 0.05. Triglycerides, very low-density lipoprotein cholesterol, and high sensitivity C-reactive protein were reduced with both the once-weekly and twice-daily exenatide regimens (P < 0.05.Conclusion: In this post hoc analysis, exenatide significantly improved a number of

  14. Planned neck dissection after weekly docetaxel and concurrent radiotherapy for advanced oropharyngeal cancer

    International Nuclear Information System (INIS)

    Tomita, Toshiki; Ozawa, Hiroyuki; Sakamoto, Koji; Fujii, Ryoichi; Ogawa, Kaoru; Fujii, Masato; Yamashita, Taku; Shinden, Seiichi

    2007-01-01

    Small oropharyngeal carcinomas with advanced neck metastases (stage N2 or greater) are common. Patients with small T with large N oropharyngeal carcinoma have high rates of local control but lower rates of regional control when treated with chemoradiotherapy. Clinical assessment after chemoradiotherapy cannot ensure the absence of neck disease. In the last 5 years, we have treated patients with T1-2 with N2-3 oropharyngeal carcinoma with weekly docetaxel radiotherapy followed by planned neck dissection (PND). Our objectives were to clarify the pathologically complete response (CR) rate of neck metastasis after weekly docetaxel radiotherapy, to identify the clinical predictor of residual neck disease, and to determine the mobidity of planned neck dissection. After chemoradiotherapy, all 12 patients had a complete response at the primary site. We conducted 15 neck dissections. Of these, 6 (40%) had positive nodes. The pathological CR rate of neck metastasis was 58.3%, whereas overall 2-year neck control rate was 91.7%. These findings lend support to the role of PND after chemoradiotherapy in N2-3 neck disease. After chemoradiotherapy, clinical parameters including TN status, feasibility of chemoradiotherapy, largest lymph node size or size reduction in MRI, did not identify patients with residual neck disease. We conducted selective neck dissection (SND) in 80% of patients. SND as PND appears to be appropriate in this group of patients because of the low incidence of complications. A further cohort study including the comparison of PND nonenforcement group is necessary to clarify the validity of the addition of PND in weekly docetaxel radiotherapy. (author)

  15. Effect of a nutrition education programme on nutritional status of ...

    African Journals Online (AJOL)

    benefits of traditional practices that are eroding because of factors such as urbanisation and modernisation. .... communal tap water was not available every day of the week. Anthropometric status of children. Table 1 indicates that ~20% ... main source of drinking water in the rural districts of KwaZuluNatal and Eastern Cape.

  16. Pattern of head growth and nutritional status of microcephalic infants ...

    African Journals Online (AJOL)

    Objective: To determine the pattern of head growth and the early postnatal nutritional status of microcephalic infants in a low-income country. Materials and Methods: A cohort study in Lagos, Nigeria in which the head growth of full-term singletons within the first postnatal check-up at 6-8weeks was evaluated using the latest ...

  17. Prematuur geboren en lage sociaal-economische status

    NARCIS (Netherlands)

    de Laat, S. A. A.; Essink-Bot, M. L.; van Wassenaer-Leemhuis, A. G.; Vrijkotte, T. G. M.

    2015-01-01

    Comparison of the association between socioeconomic status (SES) and psychosocial problems in preterm-born and term-born children. Cohort study (Amsterdam Born Children and their Development (ABCD) cohort). For 217 preterm-born children (mean gestation 34 weeks), Strengths and Difficulties

  18. Fish oil supplementation improves docosahexaenoic acid status of malnourished infants

    NARCIS (Netherlands)

    Smit, EN; Oelen, EA; Seerat, E; Boersma, ER; Muskiet, FAJ

    Aim-To investigate whether the low docosahexaenoic acid (DHA) status of malnourished, mostly breast fed, Pakistani children can be improved by fish oil (FO) supplementation. Methods-Ten malnourished children (aged 8-30 months) received 500 mg FO daily for nine weeks. The supplement contained 62.8

  19. Bullied Status and Physical Activity in Texas Adolescents

    Science.gov (United States)

    Case, Kathleen R.; Pérez, Adriana; Saxton, Debra L.; Hoelscher, Deanna M.; Springer, Andrew E.

    2016-01-01

    This study examined the association between having been bullied at school during the past 6 months ("bullied status") and not meeting physical activity (PA) recommendations of 60 minutes of daily PA during the past week among 8th- and 11th-grade Texas adolescents. Multiple logistic regression analysis was conducted to examine this…

  20. Stability Criteria - Present Status and Perspectives of Improvement

    Directory of Open Access Journals (Sweden)

    Lech Kobylinski

    2014-06-01

    Full Text Available Short historical development and present status of stability criteria is presented. Current work of the International Maritime Organisation on second generation stability criteria is critically assessed showing the advantages and week points of the project. Perspectives for improvement of the safety against stability failure are discussed, including risk assessment methods and goal oriented approach to stability problems.

  1. Maternal vitamin D status and offspring bone fractures

    DEFF Research Database (Denmark)

    Petersen, Sesilje Bondo; Olsen, Sjurdur Frodi; Mølgaard, Christian

    2014-01-01

    offspring bone mass and related that to maternal vitamin D status. METHODS: The Danish Fetal Origins 1988 Cohort recruited 965 pregnant women during 1988-89 at their 30th gestation week antenatal midwife visit. A blood sample was drawn and serum was stored, which later was analyzed for the concentration...

  2. Safety system status monitoring

    International Nuclear Information System (INIS)

    Lewis, J.R.; Morgenstern, M.H.; Rideout, T.H.; Cowley, P.J.

    1984-03-01

    The Pacific Northwest Laboratory has studied the safety aspects of monitoring the preoperational status of safety systems in nuclear power plants. The goals of the study were to assess for the NRC the effectiveness of current monitoring systems and procedures, to develop near-term guidelines for reducing human errors associated with monitoring safety system status, and to recommend a regulatory position on this issue. A review of safety system status monitoring practices indicated that current systems and procedures do not adequately aid control room operators in monitoring safety system status. This is true even of some systems and procedures installed to meet existing regulatory guidelines (Regulatory Guide 1.47). In consequence, this report suggests acceptance criteria for meeting the functional requirements of an adequate system for monitoring safety system status. Also suggested are near-term guidelines that could reduce the likelihood of human errors in specific, high-priority status monitoring tasks. It is recommended that (1) Regulatory Guide 1.47 be revised to address these acceptance criteria, and (2) the revised Regulatory Guide 1.47 be applied to all plants, including those built since the issuance of the original Regulatory Guide

  3. Safety system status monitoring

    Energy Technology Data Exchange (ETDEWEB)

    Lewis, J.R.; Morgenstern, M.H.; Rideout, T.H.; Cowley, P.J.

    1984-03-01

    The Pacific Northwest Laboratory has studied the safety aspects of monitoring the preoperational status of safety systems in nuclear power plants. The goals of the study were to assess for the NRC the effectiveness of current monitoring systems and procedures, to develop near-term guidelines for reducing human errors associated with monitoring safety system status, and to recommend a regulatory position on this issue. A review of safety system status monitoring practices indicated that current systems and procedures do not adequately aid control room operators in monitoring safety system status. This is true even of some systems and procedures installed to meet existing regulatory guidelines (Regulatory Guide 1.47). In consequence, this report suggests acceptance criteria for meeting the functional requirements of an adequate system for monitoring safety system status. Also suggested are near-term guidelines that could reduce the likelihood of human errors in specific, high-priority status monitoring tasks. It is recommended that (1) Regulatory Guide 1.47 be revised to address these acceptance criteria, and (2) the revised Regulatory Guide 1.47 be applied to all plants, including those built since the issuance of the original Regulatory Guide.

  4. The Effect of a 12-Week Health Training Program on Selected Anthropometric and Biochemical Variables in Middle-Aged Women

    Directory of Open Access Journals (Sweden)

    Wanda Pilch

    2017-01-01

    Full Text Available Regular moderate physical activity positively affects health, fitness, and body composition; it regulates the pro- and anti-inflammatory cytokines levels. Vitamin D plays an important regulatory role; its adequate levels correlate with low values of inflammation markers and an increase in muscle strength and fitness in exercising people. The study’s aim was to evaluate changes in somatic variables, oxidative stress, and inflammation markers, as well as blood calcidiol concentration in middle-aged healthy women after 12 weeks of aerobics classes—endurance exercises, including choreographic sequences, aiming to improve fitness and motor coordination. The training led to a significant reduction of body mass and fat tissue; it induced an increase in lean body mass. After the 12-week training program, plasma antioxidant status increased (0.65 ± 0.21, p<0.01 and the concentration of lipid peroxidation products decreased (0.07 ± 0.02, p<0.001. A significant increase in plasma antioxidant status associated with training could have reduced the level of proinflammatory interleukin as indicated by a positive correlation between these variables (rs = 0.64, p<0.05. The study proved that a 12-week health training program in physically inactive middle-aged women might provide improvements in their anthropometric parameters and selected biochemical indicators.

  5. The Effect of a 12-Week Health Training Program on Selected Anthropometric and Biochemical Variables in Middle-Aged Women.

    Science.gov (United States)

    Pilch, Wanda; Tota, Łukasz; Sadowska-Krępa, Ewa; Piotrowska, Anna; Kępińska, Magdalena; Pałka, Tomasz; Maszczyk, Adam

    2017-01-01

    Regular moderate physical activity positively affects health, fitness, and body composition; it regulates the pro- and anti-inflammatory cytokines levels. Vitamin D plays an important regulatory role; its adequate levels correlate with low values of inflammation markers and an increase in muscle strength and fitness in exercising people. The study's aim was to evaluate changes in somatic variables, oxidative stress, and inflammation markers, as well as blood calcidiol concentration in middle-aged healthy women after 12 weeks of aerobics classes-endurance exercises, including choreographic sequences, aiming to improve fitness and motor coordination. The training led to a significant reduction of body mass and fat tissue; it induced an increase in lean body mass. After the 12-week training program, plasma antioxidant status increased (0.65 ± 0.21, p < 0.01) and the concentration of lipid peroxidation products decreased (0.07 ± 0.02, p < 0.001). A significant increase in plasma antioxidant status associated with training could have reduced the level of proinflammatory interleukin as indicated by a positive correlation between these variables ( r s = 0.64, p < 0.05). The study proved that a 12-week health training program in physically inactive middle-aged women might provide improvements in their anthropometric parameters and selected biochemical indicators.

  6. Reference range of the weekly uterine cervical length at 8 to 38 weeks of gestation in the center of Iran

    OpenAIRE

    Jafari-Dehkordi, Esmat; Adibi, Atoosa; Sirus, Mehri

    2015-01-01

    Background: There is an inverse relation between the uterine cervical length during pregnancy and the frequency of preterm delivery. The purpose of this study was to construct a chart and evaluate the cervical length at 8 to 38 weeks of normal gestation in the center of Iran. Materials and Methods: Uterine cervical length was measured on 930 asymptomatic pregnant women by abdominal ultrasonographic technique. For statistical evaluation, regression analysis and calculation of percentiles w...

  7. Factors associated with delivery at or after 28 weeks gestation in women with bulging fetal membranes before 26 weeks gestation.

    Science.gov (United States)

    Ito, Akiko; Maseki, Yoshiaki; Ikeda, Sayako; Tezuka, Atsuko; Kuribayashi, Momoko; Furuhashi, Madoka

    2017-09-01

    To elucidate the factors that contribute to prolonged pregnancy and promote neonate survival in women with bulging fetal membranes. A database was reviewed to identify women with singleton pregnancies who underwent amniocentesis on admission to determine amniotic fluid neutrophil elastase levels before 26 + 0 weeks gestation between July 2001 and January 2015. Following delivery, the placentas of these patients were examined for histologic chorioamnionitis. Ninety-seven women delivered before 28 weeks gestation, and 117 women delivered at or after 28 weeks gestation. Rescue cerclage performed via the McDonald procedure (adjusted odds ratio [aOR]: 3.78; 95% confidence interval [CI]: 1.35-11.80) was associated with a higher likelihood of reaching at least 28 weeks gestation before delivery, whereas protruding membranes (aOR: 0.38; 95% CI: 0.18-0.78), elevated amniotic neutrophil elastase levels (≥0.15 μg/ml) (aOR, 0.41; 95% CI: 0.20-0.82) and elevated peripheral C-reactive protein levels (≥0.4 mg/dl) (aOR: 0.34; 95% CI: 0.180.65) were associated with a significantly reduced likelihood of reaching this gestational age before delivery. Among women who underwent rescue cerclage, amniorrhexis was associated with a negative prognosis (aOR: 0.18; 95% CI: 0.05-0.51). Intra-amniotic inflammation, protrusion of fetal membranes and amniorrhexis are factors that may prevent pregnancy prolongation. Rescue cerclage improves pregnancy outcomes.

  8. Zinc and iron status during pregnancy of Filipino women.

    Science.gov (United States)

    de Jong, Nynke; Romano, Aurora B Ampong; Gibson, Rosalind S

    2002-01-01

    Low birthweight is associated with maternal anaemia and, in some circumstances, with low iron and zinc status, but this relationship has not been investigated in the Philippines. In this study, we assessed the prevalence of anaemia and suboptimal iron and zinc status in pregnant women from three geographical regions (mountain, coast, city) of Zamboanga del Sur province at 24 weeks (n = 305). and again at 36 weeks (n = 127), gestation. At 24 weeks, 34% were anaemic (i.e., haemoglobin values (i.e., 11 x 10(9)/L; 19%) and serum C-reactive protein (> 15 mg/L; 3%). Of the women surveyed, 20% were iron depleted but not anaemic, and 15% were zinc deficient (i.e., serum zinc values at 24 weeks gestation had infants with lower birthweights than those with values > or = 105 g/L and > or = 7.1 micromol/L, respectively. However, in the multivariate model, the contribution of maternal haemoglobin to the variance in birthweight at 24 weeks gestation was non-significant, although modest for serum zinc. Anaemia and/or suboptimal zinc status during pregnancy may be related to low birthweight in the Philippines, and their aetiology deserves further study.

  9. Physical and psychological benefits of once-a-week Pilates exercises in young sedentary women: A 10-week longitudinal study.

    Science.gov (United States)

    Tolnai, Nóra; Szabó, Zsófia; Köteles, Ferenc; Szabo, Attila

    2016-09-01

    Pilates exercises have several demonstrated physical and psychological benefits. To date, most research in this context was conducted with symptomatic or elderly people with few dependent measures. The current study examined the chronic or longitudinal effects of very low frequency, once a week, Pilates training on several physical and psychological measures, over a 10-week intervention, in young, healthy, and sedentary women. Further, the study gauged the acute effects of Pilates exercises on positive- and negative affect in 10 exercise sessions. Compared to a control group, the Pilates group exhibited significant improvements in skeletal muscle mass, flexibility, balance, core- and abdominal muscle strength, body awareness, and negative affect. This group also showed favorable changes in positive (22.5% increase) and negative affect (12.2% decrease) in nine out of ten exercise sessions. This work clearly demonstrates the acute and chronic benefits of Pilates training on both physical and psychological measures. It also reveals that even only once a week Pilates training is enough to trigger detectable benefits in young sedentary women. While this frequency is below the required levels of exercise for health, it may overcome the 'lack of time' excuse for not exercising and subsequently its tangible benefits may positively influence one's engagement in more physical activity. Copyright © 2016 Elsevier Inc. All rights reserved.

  10. Influence of weeks of circadian misalignment on leptin levels

    Directory of Open Access Journals (Sweden)

    June Nguyen

    2009-12-01

    Full Text Available June Nguyen, Kenneth P Wright JrDepartment of Integrative Physiology, Sleep and Chronobiology Laboratory, University of Colorado, Boulder, CO, USAAbstract: The neurobiology of circadian, wakefulness–sleep, and feeding systems interact to influence energy homeostasis. Sleep and circadian disruptions are reported to be associated with increased risk of diabetes and obesity, yet the roles of energy balance hormones in these associations are largely unknown. Therefore, in the current study we aimed to assess the influence of several weeks of circadian misalignment (sleep and wakefulness occurring at an inappropriate biological time on the anorexigenic adipocyte hormone leptin. We utilized data from a previous study designed to assess physiological and cognitive consequences of changes in day length and light exposure as may occur during space flight, including exploration class space missions and exposure to the Martian Sol (day length. We hypothesized that circadian misalignment during an exploration class spaceflight simulation would reduce leptin levels. Following a three-week ~8 hours per night home sleep schedule, 14 healthy participants lived in the laboratory for more than one month. After baseline data collection, participants were scheduled to either 24.0 or 24.6 hours of wakefulness–sleep schedules for 25 days. Changes in the phase of the circadian melatonin rhythm, sleep, and leptin levels were assessed. Half of participants analyzed exhibited circadian misalignment with an average change in phase angle from baseline of ~4 hours and these participants showed reduced leptin levels, sleep latency, stage 2 and total sleep time (7.3 to 6.6 hours and increased wakefulness after sleep onset (all P < 0.05. The control group remained synchronized and showed significant increases in sleep latency and leptin levels. Our findings indicate that weeks of circadian misalignment, such as that which occurs in circadian sleep disorders, alters leptin

  11. Small Worlds Week: Raising Curiosity and Contributing to STEM

    Science.gov (United States)

    Ng, C.; Mayo, L.; Stephenson, B. E.; Keck, A.; Cline, T. D.; Lewis, E. M.

    2015-12-01

    Dwarf planets, comets, asteroids, and icy moons took center stage in the years 2014-2015 as multiple spacecraft (New Horizons, Dawn, Rosetta, Cassini) and ground-based observing campaigns observed these small and yet amazing celestial bodies. Just prior to the historic New Horizons encounter with the Pluto system, NASA celebrated Small Worlds Week (July 6-10) as a fully online program to highlight small worlds mission discoveries. Small Worlds Week leveraged the infrastructure of Sun-Earth Days that included a robust web design, exemplary education materials, hands-on fun activities, multimedia resources, science and career highlights, and a culminating event. Each day from July 6-9, a new class of solar system small worlds was featured on the website: Monday-comets, Tuesday-asteroids, Wednesday-icy moons, and Thursday-dwarf planets. Then on Friday, July 10, nine scientists from Goddard Space Flight Center, Jet Propulsion Laboratory, Naval Research Laboratory, and Lunar and Planetary Institute gathered online for four hours to answer questions from the public via Facebook and Twitter. Throughout the afternoon the scientists worked closely with a social media expert and several summer interns to reply to inquirers and to archive their chats. By all accounts, Small Worlds Week was a huge success. The group plans to improve and replicate the program during the school year with a more classroom focus, and then to build and extend the program to be held every year. For more information, visit http:// sunearthday.nasa.gov or catch us on Twitter, #nasasww.

  12. Gastrointestinal tolerability with ibandronate after previous weekly bisphosphonate treatment

    Directory of Open Access Journals (Sweden)

    Richard Derman

    2009-09-01

    Full Text Available Richard Derman1, Joseph D Kohles2, Ann Babbitt31Department of Obstetrics and Gynecology, Christiana Hospital, Newark, DE, USA; 2Roche, Nutley, NJ, USA; 3Greater Portland Bone and Joint Specialists, Portland, ME, USAAbstract: Data from two open-label trials (PRIOR and CURRENT of women with postmenopausal osteoporosis or osteopenia were evaluated to assess whether monthly oral and quarterly intravenous (IV ibandronate dosing improved self-reported gastrointestinal (GI tolerability for patients who had previously experienced GI irritation with bisphosphonate (BP use. In PRIOR, women who had discontinued daily or weekly BP treatment due to GI intolerance received monthly oral or quarterly IV ibandronate for 12 months. The CURRENT subanalysis included women receiving weekly BP treatment who switched to monthly oral ibandronate for six months. GI symptom severity and frequency were assessed using the Osteoporosis Patient Satisfaction Questionnaire™. In PRIOR, mean GI tolerability scores increased significantly at month 1 from screening for both treatment groups (oral: 79.3 versus 54.1; IV: 84.4 versus 51.0; p < 0.001 for both. Most patients reported improvement in GI symptom severity and frequency from baseline at all post-screening assessments (>90% at Month 10. In the CURRENT subanalysis >60% of patients reported improvements in heartburn or acid reflux and >70% indicated improvement in other stomach upset at month 6. Postmenopausal women with GI irritability with daily or weekly BPs experienced improvement in symptoms with extended dosing monthly or quarterly ibandronate compared with baseline.Keywords: ibandronate, osteoporosis, bisphosphonate, gastrointestinal

  13. Earth Science Week 2009, "Understanding Climate", Highlights and News Clippings

    Energy Technology Data Exchange (ETDEWEB)

    Robeck, Edward C. [American Geological Inst., Alexandria, VA (United States)

    2010-01-05

    The American Geological Institute (AGI) proposes to expand its influential Earth Science Week Program in 2009, with the support of the U.S. Department of Energy, to disseminate DOE's key messages, information, and resources on climate education and to include new program components. These components, ranging from online resources to live events and professional networks, would significantly increase the reach and impact of AGI's already successful geoscience education and public awareness effort in the United States and abroad in 2009, when the campaign's theme will be "Understanding Climate."

  14. Teaching Co-Design Games in Five Weeks

    DEFF Research Database (Denmark)

    Brandt, Eva; Kjærgård, Sarasiff; Risak Schou, Gudrun

    2011-01-01

    . It is important in order to prepare students for a career as designers. The paper reports from an intense five weeks course about developing and using design games as a frame for design-oriented collaborations with people outside the core design team. Co-design is about making room for people with diverse...... interests, roles and responsibilities in rehearsing the future. Using the game metaphor to stage and engage everyone is a valuable format for collaborative inquiry and co-creating future visions – in other words exploring diversity and creating unity about values and goals. The professional designer...

  15. Dose Estimation from Daily and Weekly Dosimetry Data

    Energy Technology Data Exchange (ETDEWEB)

    Ostrouchov, G.

    2001-11-16

    Statistical analyses of data from epidemiologic studies of workers exposed to radiation have been based on recorded annual radiation doses (yearly dose of record). It is usually assumed that the dose values are known exactly, although it is generally recognized that the data contain uncertainty due to measurement error and bias. In our previous work with weekly data, a probability distribution was used to describe an individual's dose during a specific period of time and statistical methods were developed for estimating it from weekly film dosimetry data. This study showed that the yearly dose of record systematically underestimates doses for Oak Ridge National Laboratory (ORNL) workers. This could result in biased estimates of dose-response coefficients and their standard errors. The results of this evaluation raise serious questions about the suitability of the yearly dose of record for direct use in low-dose studies of nuclear industry workers. Here, we extend our previous work to use full information in Pocket meter data and develop the Data Synthesis for Individual Dose Estimation (DSIDE) methodology. Although the DSIDE methodology in this study is developed in the context of daily and weekly data to produce a cumulative yearly dose estimate, in principle it is completely general and can be extended to other time period and measurement combinations. The new methodology takes into account the ''measurement error'' that is produced by the film and pocket-meter dosimetry systems, the biases introduced by policies that lead to recording left-censored doses as zeros, and other measurement and recording practices. The DSIDE method is applied to a sample of dose histories obtained from hard copy dosimetry records at ORNL for the years 1945 to 1955. First, the rigorous addition of daily pocket-meter information shows that the negative bias is generally more severe than was reported in our work based on weekly film data only, however, the

  16. SPIRAL2 Week 2011 - Slides of the presentations

    International Nuclear Information System (INIS)

    Gales, S.; Jacquemet, M.; Lewitowicz, M.; Petit, E.; Biarrote, J.L.; Uriot, D.; Thuillier, T.; Peaucelle, C.; Barue, C.; Van Hille, C.; Bernaudin, P.E.; Galdemard, P.; Ausset, P.; Dolegieviez, P.; Levallois, R.; Marchetto, M.; Pasini, M.; Quiclet, M.; Danna, O.; Lunney, D.; Di Giacomo, M.

    2013-01-01

    The main goal of the meeting is to present and discuss the current status of the SPIRAL2 project at GANIL in front of a large community of scientists and engineers. The program of the meeting will include presentations on scientific and technical developments related to the baseline project, experiments and theory. The main topics to be discussed at the conference have been: -) Driver Accelerators, -) Production of radioactive ion beams (RIB), -) Safety, -) RIB Facilities Worldwide (FAIR, Riken Nishina Center, SPES project, FRIB project) -) FP7 SPIRAL2 Preparatory Phase, -) Experiments with RIB and Theory. This document is made up of the slides of the presentations

  17. Health status evaluation in extremely premature infants

    Directory of Open Access Journals (Sweden)

    M. Yu. Arkhipova

    2016-01-01

    Full Text Available The health status was analyzed in extremely preterm infants at a postconceptual age of 38–40 weeks and in the first year of life. All the infants in the analyzed group were shown to have respiratory disorders, severe perinatal CNS lesions, and the high incidence of bronchopulmonary dysplasia and infectious and inflammatory diseases. In the first year of life, these children belonged to a group of the frequently ill. Dysfunction of the digestive system and intestinal microflora and residual signs of rickets were detected in the majority of the patients; the manifestations of bronchopulmonary dysplasia persisted in 50%. 40% of the infants had disabling complications.

  18. Temporal Attributes: their Status and Subsumption

    CSIR Research Space (South Africa)

    Keet, CM

    2015-01-01

    Full Text Available -1 Australasian Computer Science Week, Sydney, NSW, Australia, 27 - 30 January 2015 Temporal Attributes: Status and Subsumption C. Maria Keet1 E.A. Nasubo Ongoma2 1 Department of Computer Science, University of Cape Town, Cape Town 7701, South Africa..., Email: mkeet@cs.uct.ac.za 2 UKZN/CSIR-Meraka Centre for Arti_cial Intelligence Research, School of Mathematics, Statistics, and Computer Science, University of KwaZulu-Natal, Durban 4000, South Africa, Email: 212562258@stu.ukzn.ac.za Abstract...

  19. Laboratory assessment of iron status in pregnancy.

    LENUS (Irish Health Repository)

    Walsh, Thomas

    2012-02-01

    BACKGROUND: Efforts to improve maternal nutrition during pregnancy prompted an observational study of the occurrence of maternal iron deficiency and its laboratory diagnosis in almost 500 pregnancies. METHODS: In this longitudinal study, the biochemical and haematological iron indices of women (n=492) attending a prenatal clinic in a Dublin maternity hospital were assessed at first booking (mean 15.9 weeks), and after 24 weeks, and 36 weeks of gestation. Full blood counts were measured. Serum ferritin (SF), zinc protoporphyrin (ZPP), and transferrin receptor (sTfR) concentrations were assayed and transferrin receptor index (sTfR-Index) was calculated. The occurrence of low values and their diagnostic values were considered. RESULTS: A high occurrence iron deficiency (ID) at first booking (SF<12 mug\\/L) had increased over six-fold by 24 weeks, and all biochemical iron indices reflected progressive iron depletion right up to term. The WHO recommended anaemia "cut-off" (Hb<110 g\\/L) was insensitive to biochemical iron deficiency at booking, missing over 90% of the low SF values (SF<12 mug\\/L) which were mostly associated with much higher Hb levels. CONCLUSIONS: This study stresses the importance of including a biochemical index of iron status in prenatal screening and supports SF as the best indicator of biochemical ID overall. sTfR was insensitive to iron deficiency in early pregnancy, whereas the sTfR-Index, as a ratio, has the potential to distinguish between ID and physiological anaemia, and may offer stability in the assessment of iron stores from early pregnancy to full term. A policy of early screening of both Hb and SF concentrations is recommended as the minimum requirement for surveillance of maternal iron status in pregnancy.

  20. Periconception Maternal Folate Status and Human Embryonic Cerebellum Growth Trajectories : The Rotterdam Predict Study

    NARCIS (Netherlands)

    Koning, Irene V; Groenenberg, Irene A L; Gotink, Anniek W; Willemsen, Sten P; Gijtenbeek, Manon; Dudink, Jeroen; Go, Attie T J I; Reiss, Irwin K M; Steegers, Eric A P; Steegers-Theunissen, Régine P M

    2015-01-01

    We aimed to investigate whether periconceptional maternal folate status affects human embryonic cerebellar size and growth trajectories. In a prospective periconceptional cohort participants filled out questionnaires and received weekly transvaginal 3D-ultrasounds between 7+0 and 12+6 weeks

  1. Refractory status epilepticus

    Directory of Open Access Journals (Sweden)

    Sanjay P Singh

    2014-01-01

    Full Text Available Refractory status epilepticus is a potentially life-threatening medical emergency. It requires early diagnosis and treatment. There is a lack of consensus upon its semantic definition of whether it is status epilepticus that continues despite treatment with benzodiazepine and one antiepileptic medication (AED, i.e., Lorazepam + phenytoin. Others regard refractory status epilepticus as failure of benzodiazepine and 2 antiepileptic medications, i.e., Lorazepam + phenytoin + phenobarb. Up to 30% patients in SE fail to respond to two antiepileptic drugs (AEDs and 15% continue to have seizure activity despite use of three drugs. Mechanisms that have made the treatment even more challenging are GABA-R that is internalized during status epilepticus and upregulation of multidrug transporter proteins. All patients of refractory status epilepticus require continuous EEG monitoring. There are three main agents used in the treatment of RSE. These include pentobarbital or thiopental, midazolam and propofol. RSE was shown to result in mortality in 35% cases, 39.13% of patients were left with severe neurological deficits, while another 13% had mild neurological deficits.

  2. A clean environmental week: Let the nature breathe.

    Science.gov (United States)

    Moustafa, Khaled

    2017-11-15

    High levels of CO 2 emissions in the atmosphere and toxic pollutants in air, water and food have serious repercussions on all life's systems, including living beings, environment and economy. Everyone on the Earth is concerned by pollution in some way or another, no matter where and how the pollution is produced as airborne and foodborne pollutants could circulate around the world in different ways, through for example climate components (wind, rain) and/or import and export of foodstuffs. Similarly to living beings that take advantage of day-night circadian rhythms to recover after diurnal hardships, the environment in its entirety could also be seen as a complex living system that needs regular breaks to assimilate or ingest toxic pollutants produced during intensive and continuous industrial processes. If greenhouses gas emissions and pollution rates continue to increase at the same rates as they are nowadays, uncontrollable climate effects might be inevitable and the air quality in some crowded cities in the world might be hardly respirable in the future. A global "Clean Environmental Week" is discussed as an attempt toward reducing air pollution and CO 2 emissions through the interruption or reduction of industrial polluting activities regularly, for a week or so per year, to let the nature 'breathe' and recover from environmentally challenging pollutions. A clean environmental period of 10 days per year could reduce CO 2 emissions by about one billion tons of CO 2 per annum. Copyright © 2017 Elsevier B.V. All rights reserved.

  3. The ATLAS Overview Week in Freiburg, October 2004

    CERN Multimedia

    Smith, K.

    2004-01-01

    The first things that must be said are that the city of Freiburg is a very attractive location for such a meeting, encouraging a relaxed coming together of all sections of the ATLAS Community, and that the Week's activities were splendidly, (while unobtrusively), organised by our hosts, Karl Jakobs and Gregor Herten and their supporting team. The fine sunny weather contributed to our sense of well-being, of course, as did the quality of the local beer! (Some of our native English speaking colleagues were relieved to discover that what was described in restaurants and bars as 'Badisch' turned out, on the contrary, to be rather 'Good-ish' instead!!) The week began with pre-meetings of subgroups on Saturday and Sunday, and included lively discussions on how to commission the detector and on the nature and format of the ATLAS control room and its environs. These discussions were a clear indication of the optimism within the ATLAS community that physics is really beginning to appear on our horizon! During th...

  4. Weekly Fluctuations in Risk Tolerance and Voting Behaviour

    Science.gov (United States)

    Sanders, Jet G.; Jenkins, Rob

    2016-01-01

    Risk tolerance is fundamental to decision-making and behaviour. Here we show that individuals’ tolerance of risk follows a weekly cycle. We observed this cycle directly in a behavioural experiment using the Balloon Analogue Risk Task (Lejuez et al., 2002; Study 1). We also observed it indirectly via voting intentions, gathered from 81,564 responses across 70 opinion polls ahead of the Scottish Independence Referendum of 2014 (Study 2) and 149,064 responses across 77 opinion polls ahead of the United Kingdom European Union membership referendum of 2016 (Study 3). In all three studies, risk-tolerance decreased from Monday to Thursday before returning to a higher level on Friday. This pattern is politically significant because UK elections and referendums are traditionally held on a Thursday—the lowest point for risk tolerance. In particular, it raises the possibility that voting outcomes in the UK could be systematically risk-averse. In line with our analysis, the actual proportion of Yes votes in the Scottish Independence Referendum was 4% lower than forecast. Taken together, our findings reveal that the seven-day weekly cycle may have unexpected consequences for human decision-making. They also suggest that the day on which a vote is held could determine its outcome. PMID:27392020

  5. Prague Overview Week, September 13th-20th, 2003

    CERN Document Server

    Smith, K

    The week already began on Saturday for a number of system and sub-system meetings, but got into full swing on the Sunday, with a marathon session on how to tackle the challenging task of commissioning the full ATLAS spectrometer. The seeds of lots of ideas have already germinated and should begin to flower soon. Simulation studies of cosmic ray fluxes (and even early experimental measurements in Pit 1) have shown useful rates for the pre-beam phase of commissioning, and single beam measurements will also offer useful opportunities, in particular for trigger timing. Commissioning is clearly a topic which will continue to grow in importance during the next few years. On Monday we were welcomed by our Czech hosts to the first "official" session of the Overview Week, held in the Department of Mechanical Engineering of the Czech Technical University, (CTU), the oldest Technical University in Europe. ATLAS (Prague) includes groups from the CTU, the even longer established Charles University and the Czech Acad...

  6. A week for records… and things of record

    CERN Multimedia

    2015-01-01

    This week, the LHC set an important record on the way to the start of data taking for Run 2. At around 10.30 p.m. on Wednesday, 20 May, two bunches of particles were brought into collision at 13 TeV for the first time as part of the commissioning process for the systems that protect the detectors from stray particles. This milestone triggered ripples of excitement around the Laboratory and, coming right on schedule, is a clear sign that we are on course for physics data taking to start at the beginning of June. My congratulations go to all involved.   That was not the only record set this week: there was a sporting record as well. On Thursday, nearly 800 of you ran the traditional CERN Relay Race with 129 teams competing along with nine Nordic walkers, easily breaking the previous record of 108 teams set in 2013. However, despite so many pretenders to the crown, the course record of 10 minutes and 33 seconds set by the VELOcity team in 2013 still stands. Staying with a sporting theme, the an...

  7. National Water and Sanitation Week April 29 - May 6, 1998.

    Science.gov (United States)

    Ha Thi Khiet

    1998-01-01

    This article describes the water and sanitation activities of women's groups during National Water and Environmental Week held from April 29-May 6, 1998, in Viet Nam. Vietnamese women from the Viet Nam Women's Union (VWU) participated in concrete and practical activities in national water and sanitation programs at all administrative levels. These efforts have resulted in model villages with clean roads, sanitary sewage systems, and clean water. Poor sanitation is widespread. Water pollution has resulted in the lack of clean water for cooking among families and the spread of disease. To combat water pollution, women raise awareness of bad practices such as destruction of forests, careless disposal of garbage and human waste, use of human excrement for fertilizer and fish food, and use of unboiled water. Families are urged to have a sanitary latrine, to manage waste properly, and to use improved stoves that reduce smoke and increase fuel efficiency. VWU chapters and other women's groups are encouraged to continue to promote environmental awareness throughout the year. In 1998, the VWU made a commitment to implement actions during the week according to the Prime Minister's nationwide plan No. 200TTg. Actions included mobilization of women to preserve the purity of water resources; to limit disposal of garbage, dead animals, and excrement near water resources; to help the community build water facilities (wells, water filtering tanks, rainwater tanks), and to use only clean water for cooking and daily needs. Clean-ups should be organized every weekend. Other activities are identified.

  8. LHC 2012 proton run extended by seven weeks

    CERN Multimedia

    James Gillies

    2012-01-01

    An important piece of news that almost got lost in the excitement of the Higgs update seminar on 4 July is that the 2012 LHC proton run is to be extended.   On 3 July, a meeting was held between the CERN Management and representatives of the LHC and the experiments to discuss the merits of increasing the data target for this year in the light of the announcement to be made the following day. The conclusion was that an additional seven weeks of running would allow the luminosity goal for the year to be increased from 15 inverse femtobarns to 20, giving the experiments a good supply of data to work on during the LHC’s first long shut-down (LS1), and allowing them to make progress in determining the properties of the new particle whose discovery was announced last week. The current LHC schedule foresees proton running reaching a conclusion on 16 October, with a proton-ion run scheduled for November. In the preliminary new schedule, proton running is planned to continue until 16 December, ...

  9. Reaching First-Year Students During Orientation Week

    Directory of Open Access Journals (Sweden)

    Nancy Collins

    2011-11-01

    Full Text Available At the University of Waterloo, librarians have been expanding their outreach to first-year students during orientation week dramatically over the past three years. Efforts have included involvement in department and faculty orientation events, as well as in a campus-wide orientation initiative called “Jumpstart Friday,” which aims to educate new students about the different services on campus that can help them to “jumpstart” their success. Librarians’ increasing participation in varied orientation events has necessitated that librarians streamline their outreach efforts for new students. Most recently, librarians have been designing their communication pieces and presentations with a focus on eliciting interest and positive first impressions about the library. To spark students’ interest in the library they aim to 1 create clear and concise messaging for delivering essential information, 2 demonstrate how the library will fit into students’ lives, and 3 deliver content in a high-energy and upbeat way. In this article, the authors outline the specific outreach approaches that librarians at Waterloo are currently taking in their communications and presentations to first-year students during orientation week.

  10. Medical image of the week: granulomatous amoebic encephalitis

    Directory of Open Access Journals (Sweden)

    Chaudhury A

    2015-06-01

    Full Text Available No abstract available. Article truncated at 150 words. A 64-year-old woman with history of deceased donor kidney transplantation presented with altered mental status. MRI of the brain showed new region of T2/FLAIR hyperintensity with restricted diffusion and slight cortical enhancement in the left middle temporal lobe (Figure 1, Panel A. Her neurological exam was notable for expressive aphasia and right-sided weakness. Initial diagnosis of ischemic stroke was further evaluated due to immunosuppressive status. Her CSF showed a WBC of 12 cells/microL with 80% lymphocytes, glucose 61 mg/dL, and protein 53 mg/dL. Follow up MRI showed progression of T2/FLAIR hyperintensity, intraparenchymal hemorrhage, and peripheral patchy enhancement in the left anterior/medial temporal lobe and inferior frontal lobe suspicious for encephalitis (Figure 1, Panel B. Left temporal lobe biopsy revealed granulomatous encephalitis with microorganisms morphologically consistent with amoeba (Figure 2, and tissue cultures grew MRSA. Acanthamoeba species was confirmed by the Centers for Disease Control and Prevention (CDC with antibody testing. ...

  11. A multicenter study on the relative effectiveness of a 12-week physical training program for adults with an oncologic diagnosis.

    Science.gov (United States)

    Tran, Hoang; Lin, Cheng; Yu, Fang; Frederick, Angie; Mieras, Molly; Baccaglini, Lorena

    2016-09-01

    The purpose of this study was to examine the association between cancer survivors' socio-demographic and clinical characteristics and aerobic fitness changes following a physical training program. We assessed the association between participant's characteristics and aerobic fitness in the six-min walk test (6MWT) after a 12-week LIVESTRONG® at Young Men's Christian Association (YMCA) exercise program for adults with an oncologic diagnosis using linear mixed effects models. Fifty-one percent of participants had a breast cancer diagnosis and 22 % had received treatment within 1 year of enrollment. At baseline, participants who reported good/excellent health status performed better in the 6MWT than those who reported poor/fair health status (384.2 vs. 345.0 m, p = 0.035). After 12 weeks, all participants increased their average 6MWT performance by 54.2 m. After adjustment for age, gender, physical activity level, and smoking status, participants who were 60 years old or younger had a greater increase in the 6MWT score than participants older than 60 years (63.2 vs. 43.9 m, p = 0.041) while those who had never been YMCA members had a greater increase in the 6MWT compared to those who had ever been a YMCA member (62.2 vs. 40.3 m, p = 0.041). Overall, aerobic fitness among adults with an oncologic diagnosis increased after a 12-week exercise program, particularly among participants who were 60 years old or younger or were not YMCA members at enrollment. Participants with poorer health had lower aerobic fitness at baseline, though they had a similar positive response to the program as healthier participants. Future study designs may include randomization and an additional untreated arm.

  12. Weekly paclitaxel as metronomic palliative chemotherapy in small cell lung cancer

    Directory of Open Access Journals (Sweden)

    Vanita Noronha

    2016-01-01

    Full Text Available Background: Topotecan is the standard second line agent used in relapsed small cell lung cancer (SCLC. However, the erratic availability and the cost of the drug has been a prohibitive factor for its use in second-line setting in India. Paclitaxel has shown antitumor activity in heavily pretreated patients with SCLC. Hence, this audit was performed to study the efficacy of weekly paclitaxel as a form of metronomic therapy in the second-line setting in SCLC. Materials and Methods: Fifty-seven patients of relapsed SCLC who presented to the thoracic medical oncology unit of Tata Memorial Centre, Mumbai between January 2011 and December 2015 were selected for this analysis. Weekly paclitaxel at a dose of 80 mg/m 2 was administered until progression or development of intolerable side effects or patient refusal. Data regarding baseline demographics, previous treatment history, response rate, progression-free survival, overall survival (OS, and toxicity to weekly paclitaxel was extracted from a prospectively maintained database in the thoracic medical oncology unit and was analyzed using SPSS version 16 (IBM, New York, USA. Kaplan-Meier survival analysis was performed. Results: Median age of the cohort was 58 years (40-77 years. Etoposide with carboplatin was the regimen used in 40 patients (70.2% whereas the remaining 17 patients received etoposide with cisplatin (29.8%. Eastern Cooperative Oncology Group performance status at relapse was 1 in 3 (5.3%, 2 in 49 (86.0%, and 3 in 5 (8.7% patients. The response rate and clinical benefit rate were 9.1% (5 patients and 52.7% (29 patients, respectively. Grade 3-4 toxicities were seen in 10.5% (6 patients. The median PFS was 145 days (95% confidence interval [CI]: 116.6-173.5 days whereas the median OS was 168 days (95% CI: 112.5-223.5 days. Conclusion: Weekly paclitaxel as a second line agent in relapsed small cell cancer of the lung is a feasible and well-tolerated agent.

  13. Left Ventricular Rotational Mechanics in Preterm Infants Less Than 29 Weeks' Gestation over the First Week after Birth.

    Science.gov (United States)

    James, Adam; Corcoran, John David; Mertens, Luc; Franklin, Orla; El-Khuffash, Afif

    2015-07-01

    There is a paucity of data on left ventricular (LV) rotational physiology, twist, and torsional mechanics in preterm infants. The principal aims of the present study were to assess the feasibility and reproducibility of measuring LV rotation, twist, and torsion in preterm infants (changes in those parameters over the first week after birth. This was a prospective observational study involving preterm infants time points. Intra- and interobserver reproducibility were assessed using Bland-Altman analysis and the intraclass correlation coefficient. Fifty-one infants with a mean ± SD gestational age of 26.8 ± 1.5 weeks and a mean birth weight of 945 ± 233 g were included. There was high intra- and interobserver reproducibility for basal and apical rotation, LV twist, and LV torsion, with intraclass correlation coefficients ranging from 0.78 to 0.96 (P fashion (11.8 ± 5.0° vs 12.1 ± 6.1° vs 11.7 ± 8.3°, P = .92). Basal rotation changed from counterclockwise on day 1 to clockwise on day 7 (median, 5.5° [interquartile range, -0.3° to 8.3°] vs 4.0 [interquartile range, -4.7° to 7.2°] vs -4.5° [interquartile range, -5.8° to -2.3°], P change in LVTR (P = .60), but LVUTR increased across the same time period (P = .01). Assessment of twist, LVTR, and LVUTR is feasible in preterm infants, with acceptable reproducibility. There are increases in LV twist and torsion in addition to LVUTR, suggesting changes in LV mechanics during the first week of age. Copyright © 2015 American Society of Echocardiography. Published by Elsevier Inc. All rights reserved.

  14. Comparison of peritoneal transport characteristics at the second week and at six months of peritoneal dialysis commencement

    Directory of Open Access Journals (Sweden)

    R Balasubramaniyam

    2013-01-01

    Full Text Available Peritoneal equilibration test (PET is an important tool for managing peritoneal dialysis (PD prescription. The Kidney Disease Outcomes Quality Initiative (KDOQI guidelines suggest that the first PET be performed 4-8 weeks after PD commencement. The main reason for this delay is because of the peritoneal membrane might change its character once it is exposed to the glucose based dialysate. In this study, we compared PET 2 weeks after PD commencement to PET after 6 months to evaluate the changes in the peritoneal membrane character with time. This study included 126 patients who underwent PD initiation between March 2007 and December 2011. The PET was performed as per the standard protocol at 2 nd week and 6 th month after PD initiation. Transport status was categorized as low, low average, high average, and high as per the standard definition. There was no change in transport character in 115 patients (91.2% between the two PET measurements. When the Early PET at 2 nd week and 6 th month PET data were analyzed, no significant changes were observed in measured D/P creatinine (0.59 ± 0.14 vs. 0.62 ± 0.14 respectively P = 0.26 and D/D0 Glucose (0.46 ± 0.12 vs. 0.46 ± 0.11, P = 0.65. Using the Bland-Altman analysis the repeatability coefficients were 0.27 and 0.25 for creatinine and glucose values respectively. In our study, the PET performed at the 2 nd week are similar to that of the 6 th month PET in 91.2% of our patients and the test did not significantly change with time. In conclusion, we could do PET early at 2 nd week to assess the peritoneal membrane character and this would help in proper dialysis prescription to the patients.

  15. Comparison of peritoneal transport characteristics at the second week and at six months of peritoneal dialysis commencement.

    Science.gov (United States)

    Balasubramaniyam, R; Nirmala, V R; Yogesh, V; Sethuraman, R; Devi, S Booma; Balakrishnan, N M; Bakthavathsalam, G

    2013-09-01

    Peritoneal equilibration test (PET) is an important tool for managing peritoneal dialysis (PD) prescription. The Kidney Disease Outcomes Quality Initiative (KDOQI) guidelines suggest that the first PET be performed 4-8 weeks after PD commencement. The main reason for this delay is because of the peritoneal membrane might change its character once it is exposed to the glucose based dialysate. In this study, we compared PET 2 weeks after PD commencement to PET after 6 months to evaluate the changes in the peritoneal membrane character with time. This study included 126 patients who underwent PD initiation between March 2007 and December 2011. The PET was performed as per the standard protocol at 2(nd) week and 6(th) month after PD initiation. Transport status was categorized as low, low average, high average, and high as per the standard definition. There was no change in transport character in 115 patients (91.2%) between the two PET measurements. When the Early PET at 2(nd) week and 6(th) month PET data were analyzed, no significant changes were observed in measured D/P creatinine (0.59 ± 0.14 vs. 0.62 ± 0.14 respectively P = 0.26) and D/D0 Glucose (0.46 ± 0.12 vs. 0.46 ± 0.11, P = 0.65). Using the Bland-Altman analysis the repeatability coefficients were 0.27 and 0.25 for creatinine and glucose values respectively. In our study, the PET performed at the 2(nd) week are similar to that of the 6(th) month PET in 91.2% of our patients and the test did not significantly change with time. In conclusion, we could do PET early at 2(nd) week to assess the peritoneal membrane character and this would help in proper dialysis prescription to the patients.

  16. Improving adolescent social competence and behavior: a randomized trial of an 11-week equine facilitated learning prevention program.

    Science.gov (United States)

    Pendry, Patricia; Carr, Alexa M; Smith, Annelise N; Roeter, Stephanie M

    2014-08-01

    There is growing evidence that promoting social competence in youth is an effective strategy to prevent mental, emotional, and behavioral disorders in adulthood. Research suggests that programs delivered in collaboration with schools are particularly effective when they target social and emotional skill building, utilize an interactive instructional style, provide opportunities for youth participation and self-direction, and include explicit attempts to enhance youth social competence. A relatively new but popular approach that incorporates these characteristics is human animal interaction, which can be implemented in educational settings. We report the results from a randomized clinical trial examining the effects of an 11-week equine facilitated learning (EFL) program on the social competence and behavior of 5th-8th grade children. Children (N = 131) were recruited through referral by school counselors and school-based recruitment and then screened for low social competence. Researchers randomly assigned children to an experimental (n = 53) or waitlisted control group (n = 60). Children in the experimental group participated in an 11-week EFL program consisting of once-weekly, 90-min sessions of individual and team-focused activities, whereas children in the control group served as a wait-listed control and participated 16 weeks later. Parents of children in both groups rated child social competence at pretest and posttest. Three independent raters observed and reported children's positive and negative behavior using a validated checklist during each weekly session. Results indicated that program participation had a moderate treatment effect (d = .55) on social competence (p = .02) that was independent of pretest levels, age, gender, and referral status. Results showed that higher levels of program attendance predicted children's trajectories of observed positive (β = .500; p = .003) and negative behavior (β = -.062; p < .001) over the 11-week program.

  17. Fukushima Daiichi Status Report

    International Nuclear Information System (INIS)

    2012-01-01

    The IAEA issues regular status reports to the public on the current status of the Fukushima Daiichi Nuclear Power Plant, including information on environmental radiation monitoring, the status of workers, and current conditions on-site at the plant. The information cited in this report is compiled from official Japanese sources, including the Ministry of Economy, Trade and Industry (METI), the Nuclear and Industrial Safety Agency (NISA), the Ministry of Education, Culture, Sports, Science and Technology (MEXT), the Ministry of Land, Infrastructure, Transport and Tourism (MLIT), the Ministry of Health, Labour and Welfare (MHLW) and the Ministry of Foreign Affairs (MOFA) through the Japanese Permanent Mission in Vienna and the Cabinet's Office of the Prime Minister. Information is also provided by the Tokyo Electric Power Company (TEPCO), the operator of the Fukushima Daiichi Nuclear Power Plant.

  18. Feasibility of cetuximab given with a simplified schedule every 2 weeks in advanced colorectal cancer: a multicenter, retrospective analysis.

    Science.gov (United States)

    Bouchahda, M; Macarulla, T; Liedo, G; Lévi, F; Elez, M E; Paule, B; Karaboué, A; Artru, P; Tabernero, J; Machover, D; Innominato, P; Goldschmidt, E; Bonnet, D; Ducreux, M; Castagne, V; Guimbaud, R

    2011-12-01

    Cetuximab was approved using a weekly schedule, alone or in combination with chemotherapy (CT). However, many CT regimens in metastatic colorectal cancer (CRC) are delivered every 2 weeks (q2wks). Preliminary data suggested that a simplified schedule using cetuximab q2wks, 500 mg/m² would be equivalent to the standard weekly administration. Medical data of all patients with advanced CRC who received cetuximab q2wks were retrospectively collected and checked for consistency by an independent monitor in 4 European centers. Ninety-one patients were treated between 2005 and 2007 when the K-RAS mutational status of tumors was not determined routinely. They received a median of 4 (0-5) previous drugs, including previous weekly cetuximab in 38.5% of patients. Cetuximab q2wks was associated with an irinotecan-based regimen in 85.7% of patients. The median number of cetuximab administrations was 6 (1-23). Skin toxicity was observed in 68.2% of evaluable patients (grade 3 in 15%). Only one grade 1 allergy was reported. In the 84 patients beyond first-line therapy, response rate was 29.3%. The median progression-free survival was 3.0 months (range 2.2-3.8), and median overall survival was 9.0 months (range 6.2-11.8). Cetuximab q2wks appears safe and effective in heavily pretreated patients and convenient in combination with q2wks CT schedules.

  19. Comparing Once- versus Twice-Weekly Yoga Classes for Chronic Low Back Pain in Predominantly Low Income Minorities: A Randomized Dosing Trial

    Directory of Open Access Journals (Sweden)

    Robert B. Saper

    2013-01-01

    Full Text Available Background. Previous studies have demonstrated that once-weekly yoga classes are effective for chronic low back pain (cLBP in white adults with high socioeconomic status. The comparative effectiveness of twice-weekly classes and generalizability to racially diverse low income populations are unknown. Methods. We conducted a 12-week randomized, parallel-group, dosing trial for 95 adults recruited from an urban safety-net hospital and five community health centers comparing once-weekly (n=49 versus twice-weekly (n=46 standardized yoga classes supplemented by home practice. Primary outcomes were change from baseline to 12 weeks in pain (11-point scale and back-related function (23-point modified Roland-Morris Disability Questionnaire. Results. 82% of participants were nonwhite; 77% had annual household incomes <$40,000. The sample’s baseline mean pain intensity [6.9 (SD 1.6] and function [13.7 (SD 5.0] reflected moderate to severe back pain and impairment. Pain and back-related function improved within both groups (P<0.001. However, there were no differences between once-weekly and twice-weekly groups for pain reduction [-2.1 (95% CI -2.9, -1.3 versus −2.4 (95% CI -3.1, -1.8, P=0.62] or back-related function [-5.1 (95% CI -7.0, -3.2 versus −4.9 (95% CI -6.5, -3.3, P=0.83]. Conclusions. Twelve weeks of once-weekly or twice-weekly yoga classes were similarly effective for predominantly low income minority adults with moderate to severe chronic low back pain. This trial is registered with ClinicalTrials.gov NCT01761617.

  20. New Service Status Board

    CERN Multimedia

    2013-01-01

    On Monday 14 October, the Service Status Board for GS and IT will change. The new Status Board will be integrated with the CERN Service Portal and with the CERN Service Catalogue.   As of today, the SSB will display “Service Incidents”, “Planned Interventions” and “Service Changes”. References valid from 14 October: CERN SSB at https://cern.ch/ssb Computing SSB (previously IT SSB) at https://cern.ch/itssb   Nicole Cremel, IT and GS Service Management Support

  1. FRIB Cryogenic Plant Status

    Energy Technology Data Exchange (ETDEWEB)

    Dixon, Kelly D. [Thomas Jefferson National Accelerator Facility (TJNAF), Newport News, VA (United States); Ganni, Venkatarao [Thomas Jefferson National Accelerator Facility (TJNAF), Newport News, VA (United States); Knudsen, Peter N. [Thomas Jefferson National Accelerator Facility (TJNAF), Newport News, VA (United States); Casagranda, Fabio [Michigan State Univ., East Lansing, MI (United States)

    2015-12-01

    After practical changes were approved to the initial conceptual design of the cryogenic system for MSU FRIB and an agreement was made with JLab in 2012 to lead the design effort of the cryogenic plant, many activities are in place leading toward a cool-down of the linacs prior to 2018. This is mostly due to using similar equipment used at CHLII for the 12 GeV upgrade at JLab and an aggressive schedule maintained by the MSU Conventional Facilities department. Reported here is an updated status of the cryogenic plant, including the equipment procurement status, plant layout, facility equipment and project schedule.

  2. Maternal perceptions of their child's weight status: the GENESIS study.

    Science.gov (United States)

    Manios, Yannis; Kondaki, Katerina; Kourlaba, Georgia; Vasilopoulou, Emilia; Grammatikaki, Evangelia

    2009-08-01

    The objective of the present work was to quantify mothers' misclassification of pre-school children's weight status and to determine factors associated with the maternal misperception. A representative sample of 2287 children aged 2-5 years was examined (GENESIS study). Mothers' perceptions of their child's weight status and the children's and mothers' anthropometric and other characteristics (sociodemographic and lifestyle) were recorded. Almost 38 % of mothers underestimated their child's weight status. The frequency of underestimation was much higher among 'at risk of being overweight' and 'overweight' children (88.3 % and 54.5 %, respectively) compared with 'underweight/normal-weight' children (18.0 %, P mothers' underestimation of their child's weight status was significantly higher in boys, in children engaging in physical activity for less than 3 h/week and in children whose mothers had low education status, compared with their counterparts. Moreover, the higher the BMI-for-age Z-score, the greater the odds that the mother would underestimate her child's weight status. The current study demonstrated that more than one-third of mothers misclassify their children's weight status as being lower than the actual. Given that mother's weight perception might be an important determinant of child's body weight development, clinicians and health professionals should help mothers correctly classify their children's weight status, which could potentially help in the early prevention of overweight and obesity.

  3. Safety of 8-weeks oral administration of Arctium lappa L.

    Science.gov (United States)

    Bok, So-Hyeon; Cho, Seung Sik; Bae, Chun-Sik

    2017-01-01

    Recently, worldwide dietary reference intakes have been considered an important guideline for public health. Some governments and the World Health Organization (WHO) provide guidelines concerning dietary intake. Although an ingredient may have a history of use as a culinary material, changes in the environment over time suggest that the acceptable maximum intake each of food/culinary material should be regularly evaluated. Arctium lappa L. has been used as a culinary material for many centuries in Korea and Japan and some recent studies have reported related therapeutic effects. However, there are no reports on the safety of repeated oral administration. In this study, we evaluated the safety of a 8-weeks repeated oral intake of A. lappa. We concluded that treatment with lappa, which was within the safety range, resulted in body weight decrease and blood glucose suppression. PMID:29046701

  4. Medical image of the week: central pontine myelinolysis

    Directory of Open Access Journals (Sweden)

    Siddiqi TA

    2014-01-01

    Full Text Available A 38-year-old woman with history of alcohol abuse was admitted with generalized weakness, dehydration, alcoholic hepatitis, hyponatremia (serum sodium 116 mM/L, and cachexia (BMI 19 kg/m2. She developed hypoxemic respiratory failure after intravenous fluid resuscitation and required intubation and mechanical ventilation. Neurological exam revealed motor weakness, hyporeflexia, ataxia, and unsustained clonus. Neurology consultation was obtained and MRI revealed hyperintensity in the pons consistent with osmotic demyelination syndrome (1. Review of her records revealed her sodium level increased by 8 mM/L in first 6 hours of presentation, and then a slow increase of 4-6 mM/L daily to the normal range. She received nutritional support and aggressive physical therapy, and was discharged to skilled nursing facility after six weeks of hospitalization.

  5. Cortical Reorganisation during a 30-Week Tinnitus Treatment Program

    Science.gov (United States)

    McMahon, Catherine M.; Ibrahim, Ronny K.; Mathur, Ankit

    2016-01-01

    Subjective tinnitus is characterised by the conscious perception of a phantom sound. Previous studies have shown that individuals with chronic tinnitus have disrupted sound-evoked cortical tonotopic maps, time-shifted evoked auditory responses, and altered oscillatory cortical activity. The main objectives of this study were to: (i) compare sound-evoked brain responses and cortical tonotopic maps in individuals with bilateral tinnitus and those without tinnitus; and (ii) investigate whether changes in these sound-evoked responses occur with amelioration of the tinnitus percept during a 30-week tinnitus treatment program. Magnetoencephalography (MEG) recordings of 12 bilateral tinnitus participants and 10 control normal-hearing subjects reporting no tinnitus were recorded at baseline, using 500 Hz, 1000 Hz, 2000 Hz, and 4000 Hz tones presented monaurally at 70 dBSPL through insert tube phones. For the tinnitus participants, MEG recordings were obtained at 5-, 10-, 20- and 30- week time points during tinnitus treatment. Results for the 500 Hz and 1000 Hz sources (where hearing thresholds were within normal limits for all participants) showed that the tinnitus participants had a significantly larger and more anteriorly located source strengths when compared to the non-tinnitus participants. During the 30-week tinnitus treatment, the participants’ 500 Hz and 1000 Hz source strengths remained higher than the non-tinnitus participants; however, the source locations shifted towards the direction recorded from the non-tinnitus control group. Further, in the left hemisphere, there was a time-shifted association between the trajectory of change of the individual’s objective (source strength and anterior-posterior source location) and subjective measures (using tinnitus reaction questionnaire, TRQ). The differences in source strength between the two groups suggest that individuals with tinnitus have enhanced central gain which is not significantly influenced by the

  6. Teaching Co-Design Games in Five Weeks

    DEFF Research Database (Denmark)

    Brandt, Eva; Kjærgård, Sarasiff; Risak Schou, Gudrun

    2011-01-01

    This paper is about educating designers as codesigners and reflective practitioners. It is argued that an important goal in design pedagogy is learning the students’ strategies and tools for how to involve various stakeholders in designing, and how to deal with uncertainty and open design agendas....... It is important in order to prepare students for a career as designers. The paper reports from an intense five weeks course about developing and using design games as a frame for design-oriented collaborations with people outside the core design team. Co-design is about making room for people with diverse...... interests, roles and responsibilities in rehearsing the future. Using the game metaphor to stage and engage everyone is a valuable format for collaborative inquiry and co-creating future visions – in other words exploring diversity and creating unity about values and goals. The professional designer...

  7. The last ATLAS overview week now available on Web Lectures

    CERN Multimedia

    Jeremy Herr

    2006-01-01

    As reported in the September 2004 ATLAS eNews, the Web Lecture Archive Project, WLAP, a collaboration between the University of Michigan and CERN, has developed a synchronized system for recording and publishing educational multimedia presentations, using the Web as medium. This year, the University of Michigan team has been asked to record and publish all ATLAS Plenary sessions, as well as a large number of Physics and Computing tutorials. A significant amount of this material has already been published and can be accessed via the links below. All lectures can be viewed on any major platform with any common internet browser, either via streaming or local download (for limited bandwidth). Please enjoy the lectures and send us a note at wlap@umich.edu to tell us what you think. The newly available WLAP items relating to ATLAS is the following: ATLAS Week Plenary, CERN, 2-3 October 2006 All previous WLAP lectures are also avilable on the web.

  8. Italian singer Annalisa at CERN for a week of filming

    CERN Multimedia

    Stefania Pandolfi

    2015-01-01

    CERN welcomed Italian singer-songwriter Annalisa for a week-long visit to the Laboratory to shoot an Italian television production about the Laboratory.   Annalisa in the CERN Control Centre.   The Italian artist has a degree in physics from the University of Turin, Italy. She is a singer and songwriter, famous for her successful participation in the Italian talent show, Amici di Maria De Filippi. She has recorded four albums as solo artist and has participated twice in the Sanremo Music Festival, the most important Italian song contest. She has also received numerous Italian music awards, and has earned international recognition. Thanks to her knowledge of physics and her great influence with the Italian youth, Annalisa was selected to host an Italian television production about CERN aimed at young people. 

  9. Arch length changes from 6 weeks to 45 years.

    Science.gov (United States)

    Bishara, S E; Jakobsen, J R; Treder, J; Nowak, A

    1998-02-01

    The purpose of this study was to evaluate, on a longitudinal basis, changes in maxillary and mandibular arch length over a 45-year period. Subjects were drawn from two pools of normal individuals. Twenty-eight male and 33 female infants were evaluated longitudinally at 6 weeks, 1 year, and 2 years (before the eruption of the deciduous dentition). Fifteen males and 15 females from the Iowa Facial Growth Study were evaluated at 3, 5, 8, 13, 26, and 45 years. Arch length measurements were obtained independently by two investigators. Intra- and interexaminer reliabilities were predetermined at 0.25 and 0.5 mm, respectively. The greatest incremental increases occurred during the first two years of life. Arch length continued to increase until 13 years in the maxillary arch, and until 8 in the mandibular. Then significant and consistent decreases occurred in both arches mesial to the permanent first molars.

  10. Medical image of the week: unilateral diaphragm paralysis

    Directory of Open Access Journals (Sweden)

    Yun S

    2014-01-01

    Full Text Available No abstract available. Article truncated after 150 words. An 85 year old woman with a history of COPD presented to the emergency department (ED with shortness of breath and cyanosis of her fingers. Her symptoms have been waxing and waning since she recovered from pneumonia a year ago. A week prior to admission, she visited an outpatient clinic for worsening cough, which was treated with levofloxacin, however her shortness of breath and cyanosis persisted. O2 saturation with 4 L oxygen was 85% and CT chest without contrast showed unilateral diaphragmatic paralysis with basilar atelectasis (Figure 1. She has no history of cardiac surgery, poliomyelitis or cervical spondylosis. Also, no cervical or lung mass was found on CT scan. Her diaphragmatic paralysis is most likely secondary to phrenic nerve injury. Unilateral diaphragmatic paralysis is usually asymptomatic and does not require treatment in most of cases. However, patients with underlying lung disease can present with shortness of breath and cyanosis …

  11. Detection of triploidy at 11-14 weeks of gestation

    DEFF Research Database (Denmark)

    Engelbrechtsen, Line; Brøndum-Nielsen, Karen; Ekelund, Charlotte

    2013-01-01

    the Danish Cytogenetic Central Register and the Danish Fetal Medicine Database. RESULTS: A total of 30 triploid fetuses attended FTS. Twenty-five triploid fetuses were diagnosed as a result of abnormal FTS, a detection rate of 83%.Twenty-three fetuses were identified due to a high risk of trisomy 13, 18......OBJECTIVES: To assess the detection rate of triploidy at first-trimester screening for trisomy 21 and evaluate outcome in triploid pregnancies. METHODS: From 2008-2011, 198,427 patients women with singleton pregnancies underwent first-trimester screening (FTS) at 11+2 - 14+0 weeks of gestation. FTS....... CONCLUSION: First trimester screening for trisomy 21 also provides a high detection rate for triploidy....

  12. Cortical Reorganisation during a 30-Week Tinnitus Treatment Program.

    Directory of Open Access Journals (Sweden)

    Catherine M McMahon

    Full Text Available Subjective tinnitus is characterised by the conscious perception of a phantom sound. Previous studies have shown that individuals with chronic tinnitus have disrupted sound-evoked cortical tonotopic maps, time-shifted evoked auditory responses, and altered oscillatory cortical activity. The main objectives of this study were to: (i compare sound-evoked brain responses and cortical tonotopic maps in individuals with bilateral tinnitus and those without tinnitus; and (ii investigate whether changes in these sound-evoked responses occur with amelioration of the tinnitus percept during a 30-week tinnitus treatment program. Magnetoencephalography (MEG recordings of 12 bilateral tinnitus participants and 10 control normal-hearing subjects reporting no tinnitus were recorded at baseline, using 500 Hz, 1000 Hz, 2000 Hz, and 4000 Hz tones presented monaurally at 70 dBSPL through insert tube phones. For the tinnitus participants, MEG recordings were obtained at 5-, 10-, 20- and 30- week time points during tinnitus treatment. Results for the 500 Hz and 1000 Hz sources (where hearing thresholds were within normal limits for all participants showed that the tinnitus participants had a significantly larger and more anteriorly located source strengths when compared to the non-tinnitus participants. During the 30-week tinnitus treatment, the participants' 500 Hz and 1000 Hz source strengths remained higher than the non-tinnitus participants; however, the source locations shifted towards the direction recorded from the non-tinnitus control group. Further, in the left hemisphere, there was a time-shifted association between the trajectory of change of the individual's objective (source strength and anterior-posterior source location and subjective measures (using tinnitus reaction questionnaire, TRQ. The differences in source strength between the two groups suggest that individuals with tinnitus have enhanced central gain which is not significantly influenced by

  13. Medical image of the week: DBS polysomnogram artifact

    Directory of Open Access Journals (Sweden)

    Shetty S,

    2015-10-01

    Full Text Available A 79-year-old man with known Parkinson’s disease and status post deep brain stimulator (DBS implantation underwent an overnight polysomnogram for clinical suspicion of obstructive sleep apnea. Artifact was seen on the polysomnogram recording (Figures 1 & 2. Patient-related electrical artifacts may be seen from devices such as pacemakers, deep brain stimulators and vagal nerve simulators. Abrupt discontinuation of DBS is associated with a high likelihood of worsening of symptoms in patients with Parkinson’s disease (1. Patients with DBS are most commonly programmed in monopolar mode. Bipolar configuration, forms a short electrical dipole that affects a relatively smaller volume of tissue and generates far less artifact, suggesting that this may be an effective option in a Parkinsonian patient with indications for polysomnography (2.

  14. Rehabilitation in COPD: the long-term effect of a supervised 7-week program succeeded by a self-monitored walking program

    DEFF Research Database (Denmark)

    Ringbaek, T; Brøndum, E; Martinez, G

    2008-01-01

    Pulmonary rehabilitation in chronic obstructive pulmonary disease (COPD) improves exercise tolerance and health status, however, these effects have been shown to decline after termination of the rehabilitation program. This study has examined the long-term effect of a 7-week supervised rehabilita......Pulmonary rehabilitation in chronic obstructive pulmonary disease (COPD) improves exercise tolerance and health status, however, these effects have been shown to decline after termination of the rehabilitation program. This study has examined the long-term effect of a 7-week supervised...... rehabilitation program combined with daily self-monitored training at home on exercise tolerance and health status. Two hundred and nine consecutive COPD patients who had completed a 7-week pulmonary rehabilitation program were assessed with endurance shuttle walk test (ESWT) and the St George's Respiratory...... Questionnaire (SGRQ) at baseline, 0, 3, and 12 months after the program. Sixty-eight (32.5%) patients did not attend the 1-year follow-up. Among the 141 patients who competed the 1-year evaluation, the initial improvement after the 7-week program in the ESWT time was 180 s or 101% (p = 0.001) and in SGRQ 3...

  15. Worldwide vitamin D status

    NARCIS (Netherlands)

    van Schoor, N.M.; Lips, P.T.A.M.

    2011-01-01

    The aim of the present study is to summarize existing literature on vitamin D levels in adults in different continents and different countries woldwide. The best determinant of vitamin D status is the serum concentration of 25-hydroxyvitamin D (25(OH)D). Most investigators agree that serum 25(OH)D

  16. Status, Numbers and Influence

    Science.gov (United States)

    Melamed, David; Savage, Scott V.

    2013-01-01

    We develop a theoretical model of social influence in n-person groups. We argue that disagreement between group members introduces uncertainty into the social situation, and this uncertainty motivates people to use status characteristics to evaluate the merits of a particular opinion. Our model takes the numerical distribution of opinions and the…

  17. Assessing intravascular fluid status

    African Journals Online (AJOL)

    perfusion such as urine output. or titration of fluid therapy with the goal of optimising haemodynamic status. Most practitioners agree that an underlying theme is ... their work is the understanding that at steady state venous return and cardiac output are equal, and that factors increasing venous return would enable a greater.

  18. Fusion safety status report

    International Nuclear Information System (INIS)

    1986-10-01

    This report includes information on a) tritium handling and safety; b) activation product generation and release; c) lithium safety; d) superconducting magnet safety; e) operational safety and shielding; f) environmental impact; g) recycling, decommissioning and waste management; and h) accident analysis. Recommendations for high priority research and development are presented, as well as the current status in each area

  19. Status and the brain.

    Directory of Open Access Journals (Sweden)

    Amanda V Utevsky

    2014-09-01

    Full Text Available Social hierarchy is a fact of life for many animals. Navigating social hierarchy requires understanding one's own status relative to others and behaving accordingly, while achieving higher status may call upon cunning and strategic thinking. The neural mechanisms mediating social status have become increasingly well understood in invertebrates and model organisms like fish and mice but until recently have remained more opaque in humans and other primates. In a new study in this issue, Noonan and colleagues explore the neural correlates of social rank in macaques. Using both structural and functional brain imaging, they found neural changes associated with individual monkeys' social status, including alterations in the amygdala, hypothalamus, and brainstem--areas previously implicated in dominance-related behavior in other vertebrates. A separate but related network in the temporal and prefrontal cortex appears to mediate more cognitive aspects of strategic social behavior. These findings begin to delineate the neural circuits that enable us to navigate our own social worlds. A major remaining challenge is identifying how these networks contribute functionally to our social lives, which may open new avenues for developing innovative treatments for social disorders.

  20. Super Refractory Status Epilepticus

    African Journals Online (AJOL)

    user

    Mayer st et al did retrospective cohort study from 1 January st. 1994 to 31 March 1998 at Presbyterian Medical. Centre in Columbia, to determine the frequency, risk factors and impact on the outcome of RSE. They found out that 69% of seizures recurred after. Key Words: Super refractory status epilepticus, Zambia. Medical ...

  1. Experimental status of physics

    Indian Academy of Sciences (India)

    In a short period of time, we will have a large amount of results from -factories including ones on CP violation. In this talk, we briefly review the current experimental status of -physics. After a quick description of -facilities, we divide this vast field into two categories: (1) weak interaction and QCD, (2) unitarity triangle and ...

  2. Health status ofhostel dwellers

    African Journals Online (AJOL)

    1991-06-15

    Jun 15, 1991 ... Cape Town tuberculosis notification rates for the hostel dwellers of Langa and Guguletu emphasise the ... Department of Social Anthropology, University of Cape. Town. M. A. RAMPHELE, M.B. CH.B., D.C.H. ... health status of hostel dwellers in Langa, Nyanga and Guguletu. Health data were collected from ...

  3. Status of TRISTAN operation

    International Nuclear Information System (INIS)

    Satoh, Kotaro

    1990-01-01

    The present status of the TRISTAN operation is summarized mainly after the installation of superconducting cavities in the 1988 summer shutdown. The paper describes the initial experience of the superconducting cavity operation, the colliding operation at 30.4 GeV and the beam injection. Future improvement is also reported. (author)

  4. COMPASS Status Report 2010

    CERN Document Server

    COMPASS Collaboration

    2010-01-01

    This report gives an overview of the setup and the performance of the COMPASS experiment during the 2009 hadron beam run and describes the preparation and startup of the 2010 muon beam run with the polarised target. The status of analysis is presented both for the hadron and muon data with emphasis on the 2008/2009 hadron data.

  5. HIV status and tuberculosis

    African Journals Online (AJOL)

    User

    This hospital based study was done to estimate the magnitude of pulmonary and extra-pulmonary tuberculosis and to determine predictors of tuberculosis ..... Patient`s risk factors associated with increased risk of tuberculosis includes chronic cough, wasting, advanced age, HIV status, Diabetes Mellitus, Malnutrition etc ...

  6. Status of numerical relativity

    Indian Academy of Sciences (India)

    Keywords. Numerical relativity; gravitational waves; black hole; neutron star. Abstract. I describe the current status of numerical relativity from my personal point of view. Here, I focus mainly on explaining the numerical implementations necessary for simulating general relativistic phenomena such as the merger of compact ...

  7. NASA Armstrong Status

    Science.gov (United States)

    Jacobson, Steven R.

    2014-01-01

    Armstrong (formerly Dryden) Flight Research Center continues it's legacy of exciting work in the area of dynamics and control of advanced vehicle concepts. This status presentation highlights the research and technology development that Armstrong's Control and Dynamics branch is performing in the areas of Control of Flexible Structures and Automated Cooperative Trajectories.

  8. Angola: Country Status Report.

    Science.gov (United States)

    Bruhn, Thea C.

    A survey of the status of language usage in Angola begins with an overview of the usage and distribution of Portuguese as the official language, and the four most significant native languages and dialects spoken there: Umbundu, Kimbundu, Kikongo, and Lunda-Chokwe. The introduction of Spanish through Cuban trainers, teachers, and military advisors…

  9. HESYRL control system status

    International Nuclear Information System (INIS)

    Yao Chihyuan

    1992-01-01

    HESYRL synchrotron radiation storage ring was completed in 1989 and has been in commissioning since then. Now it has met its design specification and is ready for synchrotron light experiments. Control system of the project was completed in 1989 and some modifications were made during commissioning. This paper describes its present configuration, status and upgrading plan. (author)

  10. Assessment of Mental Status.

    Science.gov (United States)

    Finney, Glen R; Minagar, Alireza; Heilman, Kenneth M

    2016-02-01

    Assessing the mental status of patients with a neurobehavioral disorder is a critical element in the diagnosis and treatment of these patients. This assessment should always be performed after the patient's history it taken and a general physical as well as a neurologic examination is completed. The mental status examination commences with observing the patient's appearance and level of consciousness. The examiner should also pay attention to patient's social behavior, emotional state and mood. There are 3 major means of assessing a patient's mental status. One type attempts to determine if the patient is demented and the severity of the dementia as it pertains to their ability to perform activities of daily living as well as instrumental activities. A second type of assessment utilizes what may be termed as "screening tests" or "omnibus tests". These brief tests are performed independent of the patient's history and examination. The two most frequently used screening tests are the Mini-Mental Status Examination (MMSE) and the Montreal Cognitive Assessment (MoCA). The third means of assessing a patient's mental status is by using specific neuropsychological tests that focus on specific domains of cognition, such as frontal executive functions, attention, episodic verbal and visuospatial memory, declarative knowledge such as language (speech, reading and writing) and arithmetical, as well as visuospatial and perceptual abilities. These neurobehavioral, neuropsychiatric and neuropsychological assessments of patients with a cognitive decline and behavioral abnormalities should often be accompanied by laboratory tests, and neuroimaging that can help determine the underlying pathologic process so that effective therapeutic and management approaches can be provided. Copyright © 2016 Elsevier Inc. All rights reserved.

  11. Reference range of the weekly uterine cervical length at 8 to 38 weeks of gestation in the center of Iran

    Science.gov (United States)

    Jafari-Dehkordi, Esmat; Adibi, Atoosa; Sirus, Mehri

    2015-01-01

    Background: There is an inverse relation between the uterine cervical length during pregnancy and the frequency of preterm delivery. The purpose of this study was to construct a chart and evaluate the cervical length at 8 to 38 weeks of normal gestation in the center of Iran. Materials and Methods: Uterine cervical length was measured on 930 asymptomatic pregnant women by abdominal ultrasonographic technique. For statistical evaluation, regression analysis and calculation of percentiles were performed. Results: Our data show a significant decrease in uterine cervical length with increasing gestational age. The mean uterine cervical length exhibits minimal changes from 10 to 24 weeks for most women in this study, although the shortening is more prominent at 33 to 38 weeks’ gestation. The mean shortening of the uterine cervical length between the second and the ninth months was 14.82% (P < 0.05). Also, the cervical length means in trimesters 1, 2 and 3 were 39.30 ± 4.33, 38.28 ± 5.13 and 36.58 ± 4.58 mm, respectively. The third trimester showed a significant reduction (P < 0.05) in cervical length compared to the first and second trimesters (6.92% and 4.44%, respectively). New charts with the 5th, 10th, 50th, 90th, and 95th percentile are presented. Conclusion: Our study provides a new chart and reference values for normal uterine cervical length throughout gestation based on a large sample in the center of Iran. There was a progressive decrease in mean uterine cervical length with increasing gestational age in the population of this study. Our established charts for uterine cervical length throughout gestation might be more useful than a single cut-off value for more efficient prevention and management of preterm birth. PMID:26261817

  12. A comparison of early (1 week) and late (8 weeks) dipyridamole SPECT 201TI scans post-infarction

    International Nuclear Information System (INIS)

    Quinn, R.J.; Cunio, N.E.; Rahman, T.; Sinclair, S.E.; Butler, S.P.

    1998-01-01

    Full text: In the immediate post-infarction setting 201 TI is often used to assess infarct size and identify any area of residual ischaemia. We have compared both early and late dipyridamole scans in post AMI patients. Twenty six consecutive patients admitted with an AMI had an early (1 week-average 5 days: range 2-9) and late (8 weeks) 201 TI scan using both four hour redistribution and reinjection. Eighteen of the 26 had thrombolysis. SPECT was performed on each study. The studies were examined in three tomographic planes. The LV was divided into 18 segments. Each segment was scored as either perfused or nonperfused. In the early 201T I studies, 20 of 26 patients were demonstrated to have fixed defects on all 3 studies (''infarction''). The average infarct size was 3.1 segments (total 81). Only 15 patients had fixed defects on the late study with an average infarct size of 2.0 segments (total 54). There was an average decrease in the infarct size between the two studies of 1.1 segments (≤ O. 5). In terms of ischaemia, there were 21 patients who had no intervention (PTCA or CABG) between the two studies and thus the studies could be directly compared. There were 71 (average 3.4) segments with improvement on either redistribution or reinjection thus ''ischaemia'' on the early study and 54 (ave.2.6) on the late (p = NS). More importantly however, there were 4 (19%) with ischaemia on the early study not shown on the late, and 3 (14%) with ischaemia demonstrated on the late study but not the early. Thus the diagnosis of ''ischaemia'' was altered in seven patients (27%) between the two studies. In conclusion, an early post-infarction dipyridamole 201 TI scan overestimates the size of the infarcted territory. Also the timing of the 201 TI alters the ability to diagnose ''ischaemia''

  13. Cervical assessment at 22 and 27 weeks for the prediction of spontaneous birth before 34 weeks in twin pregnancies: is transvaginal sonography more accurate than digital examination?

    Science.gov (United States)

    Vayssière, C; Favre, R; Audibert, F; Chauvet, M P; Gaucherand, P; Tardif, D; Grangé, G; Novoa, A; Descamps, P; Perdu, M; Andrini, E; Janse-Marec, J; Maillard, F; Nisand, I

    2005-12-01

    This study compared the accuracy of ultrasound cervical assessment (cervical length and cervical index) and digital examination (Bishop score and cervical score) in the prediction of spontaneous birth before 34 weeks in twin pregnancies. In a prospective multicenter study, digital examination and transvaginal sonography were performed consecutively in twin pregnancies attending for routine sonography at either 22 weeks (175 women) or 27 weeks (153 women). The digital examination took place first, and the Bishop score and cervical score (cervical length minus cervical dilatation) were calculated. Ultrasound measurements were then made of cervical length and funnel length to yield the cervical index (1 + funnel length/cervical length). The association between each variable and delivery before 34 weeks was tested by the Mann-Whitney U-test. The receiver-operating characteristics (ROC) curves of the ultrasound and digital indicators were determined for both gestational age periods, and the areas under the ROC curves compared. The best cut-off values for each indicator were used to determine predictive values for delivery before 34 weeks. The median gestational age at delivery among the women included in the 22-week examination period was 36.0 (range, 21-40) weeks; 10.9% (19) gave birth spontaneously before 34 weeks. The median cervical length was 40 (range, 6-65) mm. All four parameters were predictors of delivery before 34 weeks. The areas under the ROC curves for cervical index, cervical length, Bishop score and cervical score did not differ significantly. The median gestational age at delivery among the women in the 27-week examination period was 36.0 (range, 27-40) weeks; 9.2% (14) gave birth spontaneously before 34 weeks. The median cervical length was 35 (range, 1-57) mm. All parameters except the Bishop score were predictors of delivery before 34 weeks. The likelihood ratio of the positive and negative tests for cervical length digital examination at the 27-week

  14. One Year Sustainability of Risk Factor Change from a 9-Week Workplace Intervention

    Directory of Open Access Journals (Sweden)

    Elaine C. Rush

    2009-01-01

    Full Text Available We examined the effect of a 9-week diet and physical activity intervention provided in the workplace by a group education session where personal dietary and physical activity goals were proposed. Measurements of anthropometry, fasting blood lipids, glucose and insulin, assays for antioxidant activity (AOA and questionnaires were completed at 0, 3, 6, 9, and 12 weeks in 50 healthy workers (50% male, mean age 46y. Followup measurements in 39 (56% male were possible at 52 weeks. At week 3 a group dietary and physical activity “motivational seminar” was held. At week 6, half the group were supplied daily kiwifruit for 3 weeks with cross over at week 9 until week 12. Compared to baseline, lipid, glucose, insulin and AOA measurements were improved at 12 and 52 weeks. Body measurements did not change. Group diet and physical activity advice reinforced over 9 weeks is associated with a sustained improvement in cardiovascular risk factors at 52 weeks.

  15. One Year Sustain ability of Risk Factor Change from a 9-Week Workplace Intervention

    International Nuclear Information System (INIS)

    Rush, E.C.; Cumin, M.B.; Migriauli, L.; Ferguson, L.R.; Plank, L.D.

    2010-01-01

    We examined the effect of a 9-week diet and physical activity intervention provided in the workplace by a group education session where personal dietary and physical activity goals were proposed. Measurements of anthropometry, fasting blood lipids, glucose and insulin, assays for antioxidant activity (AOA) and questionnaires were completed at 0, 3, 6, 9, and 12 weeks in 50 healthy workers (50% male, mean age 46y). Followup measurements in 39 (56% male) were possible at 52 weeks. At week 3 a group dietary and physical activity motivational seminar was held. At week 6, half the group were supplied daily kiwifruit for 3 weeks with cross over at week 9 until week 12. Compared to baseline, lipid, glucose, insulin and AOA measurements were improved at 12 and 52 weeks. Body measurements did not change. Group diet and physical activity advice reinforced over 9 weeks is associated with a sustained improvement in cardiovascular risk factors at 52 weeks.

  16. Announcement: Sleep Awareness Week, April 23-29, 2017.

    Science.gov (United States)

    2017-04-21

    Sleep Awareness Week, the National Sleep Foundation's annual campaign to educate the public about the importance of sleep in health and safety, will be observed April 23-29, 2017. The amount of sleep a person needs changes with age. Adults need ≥7 hours each night to promote optimal health and well-being (1); children and adolescents require even more sleep. Sleep needs decrease from 12-16 hours of sleep per 24 hours (including naps) for infants aged 4-12 months to 8-10 hours of sleep for teenagers aged 13-18 years (2). Children who regularly sleep less than the recommended amount are more likely to have behavior and learning problems, physical and mental health conditions such as obesity, diabetes, depression, or injuries (2). A regular bedtime routine can help children get adequate sleep. The American Academy of Pediatrics provides advice for parents at https://www.healthychildren.org/English/healthy-living/sleep/. Additional details about how much sleep is recommended across a lifespan is available at https://www.cdc.gov/sleep/about_sleep/how_much_sleep.html.

  17. Impressions from the ATLAS Overview Week in Stockholm

    CERN Multimedia

    De Jong, P.; Gowdy, S.

    2006-01-01

    Paul de Jong: "What a very nice city Stockholm in the summer turned out to be! The architecture, the relaxed style of the city and its islands and bridges, the terraces with people out on the streets until late at night made this a special trip. We visited many cool and trendy places, unfortunately many of those places are probably now a lot less cool and trendy after visits of so many physicists in shorts and white socks in sandals. A big applause for the organizers for a fine meeting, and getting us into the Stockholm city hall and the superb Wasa museum. (left) The Golden room of Stockholm City Hall. (right) Muriel was not the only one in the room entertaining noble dreams during the reception in the Golden Room of the Stockholm City Hall... ATLAS is a monstrously complicated piece of apparatus. It will be very impressive when it is finished and works, but there are so many places where things can go wrong. If I must name a single highlight of the week: I found the technical coordination of t...

  18. Infant distress at five weeks of age and caregiver frustration.

    Science.gov (United States)

    Fujiwara, Takeo; Barr, Ronald G; Brant, Rollin; Barr, Marilyn

    2011-09-01

    To investigate the differential association of three modes (fussing, crying, unsoothable crying) and three properties (duration/day, frequency/day, maximum bout length) of infant distress with daily caregiver frustration. Replicated cross-sectional studies were completed in Vancouver, British Columbia (n = 1065) and Seattle, Washington (n = 1857). Infant fussing, crying, and unsoothable crying and caregiver frustration were measured daily for 4 days at 5 weeks of age by the Baby's Day Diary. Generalized estimating equation models were used to predict caregiver frustration from nine measurements of distress. In Vancouver, measurements of distress significantly associated with caregiver frustration in decreasing order of magnitude were as follow: (1) maximum bout length of unsoothable crying; (2) duration/day of crying; and (3) frequency of unsoothable crying and duration/day of fussing. In Seattle, associated measurements of distress were: (1) maximum bout length of unsoothable crying; (2) maximum bout length and duration/day of crying, frequency of unsoothable crying, and duration/day of fussing; and (3) frequency/day of crying. Daily caregiver frustration is associated differentially with different modes and properties of infant distress. Specifically, maximum bout length of unsoothable crying was most strongly related in both sites. Additionally, frequency/day of unsoothable crying and duration/day of crying and of fussing were significantly associated at both sites. Copyright © 2011 Mosby, Inc. All rights reserved.

  19. MR imaging of pontine infarction within 2 weeks after ictus

    Energy Technology Data Exchange (ETDEWEB)

    Uchino, Akira; Hata, Hirofumi; Ohno, Masato (Kyushu Rosai Hospital, Fukuoka (Japan))

    1991-08-01

    Magnetic resonance (MR) images of 10 patients with pontine infarction were reviewed. A total of 17 examinations were performed on a 1.5 Tesla high-field scanner (GE) within two weeks after ictus. The infarcted area was detected by MR as early as 20 hours after stroke in one case. However, MR images obtained in two cases three and nine hours after onset were unremarkable. It is therefore suggested that follow-up study should be performed when initial MR images within 20 hours postictus are normal. T{sub 1}-weighted images at four, nine and twelve days after ictus were interpreted as normal. In two of these three examinations, the infarcted areas were clearly demonstrated as hyperintense lesions on T{sub 2}-weighted images. In the other examination, however, an area of mildly increased signal intensity was seen on T{sub 2}-weighted images. This case suggests that the fogging effect is also observed on MR imaging and that a small pontine infarction may be overlooked during the subacute stage. Basilar artery occlusion was detected as an absence-of-flow void in three of the ten patients. In conclusion, MR imaging proved to be a relatively useful diagnostic modality for evaluating acute and subacute pontine infarction. (author).

  20. Medical Image of the week: left ventricular non-compaction

    Directory of Open Access Journals (Sweden)

    Khoubyari R

    2016-06-01

    Full Text Available No abstract available. Article truncated at 150 words. A 38-year-old woman with history of type 2 diabetes mellitus and hypertension presented to emergency department with worsening exertional dyspnea and orthopnea for the past 2-3 months. She also reported a 14 pound weight gain within the 2 weeks prior to presentation. She denied any prior history of cardiac or pulmonary disease. Also, there was no family history of heart disease. She denies any recent sick contacts, smoking, alcohol drinking, or substance abuse. Physical exam revealed jugular venous pressure of 10 cm H2O and significant bilateral lower extremity pitting edema. Chest x-ray showed an enlarged cardiac silhouette. Brain naturetic peptide (BNP was 2,917 pg/mL. A subsequent echocardiogram revealed a left ventricular (LV ejection fraction of 23% with severe global LV hypokinesia with moderate mitral regurgitation. Thyroid panel as well as iron panel were within normal range. Other laboratories were unremarkable. For the new onset systolic heart failure, a coronary angiography was ...

  1. Weeks Island gravity stable CO2 pilot: Final report

    Energy Technology Data Exchange (ETDEWEB)

    Johnston, J.R.; Perry, G.E.

    1989-01-01

    The Weeks Island ''S'' sand Reservoir B (''S'' RB) gravity-stable CO2 field test was completed during February 1988. Injection started in October 1978 and production began in January 1981 in this high-permeability, steeply-dipping sandstone reservoir. About 264,000 barrels of oil or 65 percent of the starting volume has been recovered. A 24-percent pore-volume slug of CO2 mixed with about six mole percent of natural gas (mostly methane) was injected at the start of the pilot. Since 1983, produced CO2 plus hydrocarbon gases have been recycled. CO2 usage statistics are 9.34 MCF/BO with recycle and 3.24 MCF/BO based on purchased CO2. Previous annual reports document the pilot design, implementation, and early results for the 1977 to June 1981 time period. This report is a review of early pilot history and a more detailed account of the post June 1981 results and overall interpretation. A reservoir-simulation history match of pilot performance plus core and log data from a 1983 swept-zone evaluation well are described in this report. A brief description of the production facility and an account of the corrosion control program are also included. 11 refs., 34 figs.

  2. A good week for global collaboration in particle physics

    CERN Multimedia

    2015-01-01

    This has been a good week for global collaboration in particle physics. On Wednesday, the CERN family grew by one Associate Member when we received official confirmation that the accession agreement signed last year had been ratified by the Turkish parliament, and on Thursday, we signed a new cooperation agreement with the US.   The signature of a new cooperation agreement between CERN and the US at the White House on Thursday, 7 May marks both a renewal of a long-standing friendship and a commitment to take the partnership further. Signed between CERN, the US Department of Energy and the US National Science Foundation, it is a framework agreement that paves the way for detailed accords on continued US participation in CERN’s scientific programme, and on European collaboration in projects hosted in the US, including prospective neutrino facilities. It is an agreement that is tacitly renewed every five years, unless one of the signatories signals a need to end or amend it. I am part...

  3. Neck Pain One Week after Pacemaker Generator Replacement.

    Science.gov (United States)

    Graham, Ross F; Wightman, John M

    2015-07-01

    The incidence of cardiac pacemaker implantation has risen markedly in the past three decades, making awareness of possible postprocedural complications critical to the emergency physician. This case is the first documented instance of internal jugular (IJ) deep vein thrombosis (DVT) from an uncomplicated pacemaker generator replacement. A patient presented to an Emergency Department with a 2-day history of mild left temporal headache migrating to his left neck. The patient did not volunteer this information, but review of systems revealed a temporary transvenous pacemaker inserted through the right IJ vein 1 week previously during a routine exchange of a left-sided cardiac pacemaker generator. Manipulation of the existing pacemaker wires entering the left subclavian vein was minimal. Computed tomographic angiography of the neck demonstrated near-complete thrombotic occlusion of the entire length of his left IJ vein. This required hospital admission for observation and treatment with anticoagulation. WHY SHOULD AN EMERGENCY PHYSICIAN BE AWARE OF THIS?: DVT, with thrombotic extension into adjacent vessels anywhere along the course of pacemaker wires, should be considered by the emergency provider in the evaluation of head, neck, or upper extremity symptoms after recent or remote implantation or manipulation of a transvenous cardiac pacemaker, including generator replacement. Failure to identify and treat appropriately could result in significant morbidity and mortality from airway edema, septic thrombophlebitis, superior vena cava syndrome, superior sagittal sinus thrombosis, or pulmonary embolism. Published by Elsevier Inc.

  4. Medical image of the week: tracheobronchial foreign body aspiration

    Directory of Open Access Journals (Sweden)

    Goel K

    2016-10-01

    Full Text Available No abstract available. Article truncated at 150 words. Case 1 (Figure 1 is a 58-year-old man who accidentally inhaled his insulin syringe cap while swinging on his recliner with the cap perched in his mouth. He developed a dry irritating cough. On exam he had mild stridor in the upper airways and bilateral wheezing. The insulin cap was visualized by bronchoscopy in the right mainstem bronchus and retrieved with forceps. Case 2 (Figure 2 is a 65-year-old man with chronic dysphagia and poor dentition who choked on a cashew. It took repeated coughing attempts to produce the cashew, but it was unclear whether the entire content was cleared. He then developed non-massive hemoptysis that persisted for 2 weeks. Thoracic CT showed ground glass opacities and an air fluid level in the right middle lobe. The foreign body was visualized in the right lower lobe bronchus as an endobronchial-filling defect. Bronchoscopy revealed a cashew piece in the right lower ...

  5. Neonates Born between 37 and 43 Weeks of Gestation

    Directory of Open Access Journals (Sweden)

    C. Fischer

    2012-01-01

    Full Text Available The epidemiology of meconium aspiration syndrome (MAS in term neonates is described in a population-based retrospective study of data recorded for all births from 2000 to 2007 in a French region (Burgundy. Of the 132 884 eligible term newborns, the rate of meconium-stained amniotic fluid (MSAF was 7.93%. The prevalence of severe MAS was 0.067% in the overall population. MAS rate was 0.11% at 37-38 weeks of gestation (WG, 0.20% at 39–41 WG, and 0.49% at 42-43 WG. Factors independently associated with severe MAS were identified by a case-control study, that is, thick meconium amniotic fluid, fetal tachycardia, Apgar score ≤3 at 1 minute, and birth in a level III facility. Our results confirm the high prevalence of MSAF after 37 WG but also show the low frequency of severe MAS in a period corresponding to the new international recommendations on the management of birth with MSAF.

  6. Training for fitness: reconsidering the 80-hour work week.

    Science.gov (United States)

    Caldicott, Catherine V; Holsapple, James W

    2008-01-01

    The medical literature is replete with articles about the Accreditation Council for Graduate Medical Education's 2003 resident duty hour restrictions. Most of these papers describe creative and thoughtful responses to the new system. However, others express concern that the "80-hour work week" could hamper continuity of care and educational activities. Nevertheless, if fatigue impairs resident learning and medical care quality, then work hour restrictions seem worthwhile. We add our voices to the critics' for additional reasons. Data support that fatigue occurs even with reasonable work schedules, and residents do not reliably use time off from work to rest. Regulated work schedules can interfere with adequate rehearsal of the physical and mental stamina required in certain specialties, yet patients have a right to expect their physicians to be trained in the particular demands of those specialties. Similarly, residents have a right to a realistic understanding of authentic clinical practice. Further, while self-sacrifice need not be routine, trainees should feel that occasional self-sacrifice is appropriate and acceptable for a physician. We reject uniform, arbitrary duty hour limits for all specialties. Rather, we propose that a subspecialty-based system can foster the development of the endurance, skills, and reasoning that patients and colleagues expect.

  7. Patient satisfaction with clinicians in colorectal 2-week wait clinics.

    Science.gov (United States)

    Cock, Karen; Kent, Bridie

    2017-03-23

    To determine if patient satisfaction is affected by the clinician (nurse or doctor), conducting the colorectal 2-week wait (2ww) clinics. A prospective non-randomised comparative cohort study of 339 consecutive patients (divided by blind allocation into nurse-led (n=216) and doctor-led (n=123) cohorts) conducted over a 3-month period. Patient satisfaction in both cohorts was assessed by an adapted version of the Grogan et al validated patient satisfaction questionnaire. The questionnaire was piloted first and was found to have high internal reliability (Cronbach's alpha=0.91). The study had a response rate of 78% (n=258/331) and overall satisfaction scores showed 85% (n=149/175) of patients in the nurse-led cohort and 65% (n=54/83) of patients in the doctor-led cohort strongly agreed that they were satisfied with the care they received. Mean overall satisfaction scores in the two cohorts revealed that the nurse-led cohort achieved significantly more 'strongly agree' responses than the doctor-led cohort (ppatient satisfaction was affected by the clinician conducting the 2ww clinic, in that the nurse-led cohort displayed significantly higher patient satisfaction. However, there are areas that merit further research.

  8. The Physics session at the ATLAS overview week

    CERN Multimedia

    Takai, H.

    The Physics session at the ATLAS overview week at Clermont-Ferrand will be certainly remembered by the presentation of Blaise Pascal's historical experiment repeat. And why not? He is the local hero and by the looks of his primitive measurements it does take a lot of guts to explain his results on the basis of air columns. He was also lucky that he did not have to simulate his results on modern day computers but used the Pascaline. Certainly a man ahead of his time. Of course that wasn't all. Surrounded by a chain of (luckily) extinct volcanoes, rolling hills, and superb views, Clermont-Ferrand provided the perfect backdrop for the physics discussions. It was once more seen that the physics of ATLAS is diverse and that it is healthy and doing well. Many people contributed to the success of the session. Fabiola started the session precisely at 14:00 with a summary of the most recent activities from the physics coordination. Somehow what got stuck in my mind was the very positive statistics on how many prese...

  9. Medical image of the week: neurogenic pulmonary edema

    Directory of Open Access Journals (Sweden)

    Yun S

    2014-02-01

    Full Text Available No abstract available. Article truncated at 150 words. A 79 year old woman with a history of diabetes, hypertension and subarachnoid hemorrhage presented to the emergency department (ED with altered mental status. The patient had a fall one day prior to admission, and hit her head on the ground. There was no loss of consciousness or seizure activity at that moment, however, she was found unresponsive in the bathroom the next day with brownish vomitus in the mouth and on her face. CT of the head without contrast showed a large intraparenchymal hemorrhage on the left frontal lobe with subdural hemorrhage on the right frontal and temporal lobe. Also, intraventricular blood with 1.1 cm left to right midline shift was observed (Figure 1. Although she had no history of left heart failure or pulmonary disease, physical exam showed coarse lung sound and chest X-ray showed acute change with prominence central vasculature with fluffy central airspace opacities, which were …

  10. Medical image of the week: artery of Percheron infarction

    Directory of Open Access Journals (Sweden)

    Ta TT

    2017-03-01

    Full Text Available No abstract available. Article truncated after 150 words. A 55-year-old African-American man presented to the Emergency Department for acute altered mental status which started 4 hours ago. His medical history was significant for heart failure with reduced ejection fraction, diabetes mellitus, marijuana and opioid use. On admission, the patient appeared to be in a deep sleep, unarousable, with grimacing to noxious stimuli. He occasionally moved all extremities. He was intubated for airway protection. Initial CT head non-contrast demonstrated a previous right MCA infarct, with no new acute hemorrhage. MRI/MRA brain revealed complete infarction of the artery of Percheron (AOP, likely due to a left ventricular thrombus (Figure 1. The patient remained somnolent throughout hospitalization with minimal neurologic improvement, and was ultimately transferred to a long-term care facility after a tracheostomy and PEG placement. The artery of Percheron is a rare, normal intracranial vascular variant in which a single arterial trunk originates from the posterior cerebral artery, giving rise …

  11. Effect of 8-week Aerobic Exercise and Yoga Training on Depression, Anxiety, and Quality of Life among Multiple Sclerosis Patients

    Directory of Open Access Journals (Sweden)

    Fatemeh Ahadi

    2013-04-01

    Full Text Available Objectives: Multiple sclerosis (MS is a disease of the central nervous system that results in many symptoms including mobility limitation, fatigue, cognitive dysfunction and redacted quality of life. The purpose of this study was to determine the effect of 8-weeks aerobic and yoga training on depression, anxiety and quality of life in individuals with MS. Methods: 31 women with MS (mean of age of 34.15years with Expanded Disability Status Scale scores 1.0 to 4.0, were randomly assigned to one of three groups lasting 8 weeks: treadmill training, yoga or a waiting-list control group. Treadmill training consisted of 8 weeks (24 sessions of treadmill training (30 minutes, at 40-75% of age-predicted maximum heart rate. Yoga group subjects participated in a thrice weekly 60-70 minute sessions of Hatha yoga intervention for 8 weeks. The control group followed their own routine treatment program. Depression, anxiety and quality of life were measured by Beck Depression Inventory (BDI, Beck Anxiety Inventory (BAI and Multiple Sclerosis Quality of Life-54 questionnaire (MSQOL-54 respectively. Data were analyzed by MANOVA, Tukey and paired t-tests. Results: Results indicated that intervention has improved significantly BDI score, BAI score and some MSQOL-54 scale scores in the treadmill training group and yoga group. There were significant differences between treadmill training group and yoga group in BAI score and MSQOL-54 scale scores. Discussion: These results suggest that treadmill training and yoga practice improved depression, anxiety and quality of life in people with mild to moderate MS.

  12. The Effect of a Complex (3-week Therapy on the Hip and Knee Joints in Obese Patients

    Directory of Open Access Journals (Sweden)

    Tóvári Anett

    2015-05-01

    Full Text Available Currently, overweight and obesity are the most widespread problems in life-style having a significant impact on everyday life, and thus, conduct of life. Further contributory problems may develop in patients with weight problems: deformities of the joints and skeleton (coxarthrosis and gonarthrosis, circulatory problems and arrhythmia. Overweight definitely has an effect on motion: some people are not involved in certain activities as it is impossible for them because of their weight problem. Thus, even more health problems are generated because of the overweight. The first question arising in discussing the actuality of this issue is what effect the applied therapy (massage, therapeutic exercises, electrotherapy and balneotherapy has on the knee and hip joints of patients with weight problems hospitalised in our Institute for a 3-week complex therapy. Based on my prior hypothesis, positive changes are detected in a minimum percentage in the condition of overweight or obese patients. My hypothesis was that the range of flexion and extension of the hip and knee joints would improve compared to other movements. Based on the results of the studied population (n=30, my hypothesis seems to be proven. After the 3-week complex therapy of obese patients, positive changes were found in the prearranged assessments and tests, thereby improving the general health, life-style, life quality and mental status of the patients. After the end of the complex therapy, patients were provided life-style counselling and exercise schemes to be performed in their home to maintain the achieved health status.

  13. Biomarkers of selenium status in dogs.

    Science.gov (United States)

    van Zelst, Mariëlle; Hesta, Myriam; Gray, Kerry; Staunton, Ruth; Du Laing, Gijs; Janssens, Geert P J

    2016-01-19

    Inadequate dietary selenium (Se) intake in humans and animals can lead to long term health problems, such as cancer. In view of the owner's desire for healthy longevity of companion animals, the impact of dietary Se provision on long term health effects warrants investigation. Little is currently known regards biomarkers, and rate of change of such biomarkers in relation to dietary selenium intake in dogs. In this study, selected biomarkers were assessed for their suitability to detect changes in dietary Se in adult dogs within eight weeks. Twenty-four dogs were fed a semi-purified diet with an adequate amount of Se (46.1 μg/MJ) over an 8 week period. They were then divided into two groups. The first group remained on the adequate Se diet, the second were offered a semi-purified diet with a low Se concentration (6.5 μg/MJ; 31% of the FEDIAF minimum) for 8 weeks. Weekly urine and blood was collected and hair growth measurements were performed. The urinary Se to creatinine ratio and serum Se concentration were significantly lower in dogs consuming the low Se diet from week 1 onwards, by 84% (adequate 25.3, low 4.1) and 7% (adequate 257 μg/L, low 238 μg/L) respectively. Serum and whole blood glutathione peroxidase were also significantly lower in dogs consuming the low Se diet from weeks 6 and 8 respectively. None of the other biomarkers (mRNA expression and serum copper, creatine kinase, triiodothyronine:thyroxine ratio and hair growth) responded significantly to the low Se diet over the 8 week period. This study demonstrated that urinary Se to creatinine ratio, serum Se and serum and whole blood glutathione peroxidase can be used as biomarkers of selenium status in dogs. Urinary Se to creatinine ratio and serum Se concentrations responded faster to decreased dietary Se than the other parameters. This makes these biomarkers candidates for early screening of long term effects of dietary Se provision on canine health.

  14. Status of memory loss.

    LENUS (Irish Health Repository)

    Iyer, Parameswaran Mahadeva

    2012-01-01

    A 72-year-old woman presented with first onset of seizure with no prior history of cognitive dysfunction. EEG revealed focal non-convulsive status epilepticus. MRI brain showed a left temporal non-enhancing lesion. Temporal pole biopsy showed acute neuronal necrosis and astrocyte hyperplasia together with extensive amyloid plaques and neurofibrillary tangles. Perivascular oligodendroglial hyperplasia was present. Postmortem examination revealed extensive plaque and tangle disease. Perivascular oligodendroglial hyperplasia was limited to the left temporal area. The presence of focal perivascular oligodendroglial hyperplasia in the left temporal cortex, combined with extensive plaque and tangle disease may have contributed to the focal status epilepticus in this patient. Although the presence of focal perivascular oligodendroglial hyperplasia has been reported in cases of temporal lobe epilepsy, it has not been reported as a cause of seizure in patients with Alzheimer\\'s disease previously. Further studies for clinical-pathologic correlation would be required to confirm this hypothesis.

  15. Status of MARS Code

    Energy Technology Data Exchange (ETDEWEB)

    N.V. Mokhov

    2003-04-09

    Status and recent developments of the MARS 14 Monte Carlo code system for simulation of hadronic and electromagnetic cascades in shielding, accelerator and detector components in the energy range from a fraction of an electronvolt up to 100 TeV are described. these include physics models both in strong and electromagnetic interaction sectors, variance reduction techniques, residual dose, geometry, tracking, histograming. MAD-MARS Beam Line Build and Graphical-User Interface.

  16. Status of fusion maintenance

    International Nuclear Information System (INIS)

    Fuller, G.M.

    1984-01-01

    Effective maintenance will be an essential ingredient in determining fusion system productivity. This level of productivity will result only after close attention is paid to the entire system as an entity and appropriate integration of the elements is made. The status of fusion maintenance is reviewed in the context of the entire system. While there are many challenging developmental tasks ahead in fusion maintenance, the required technologies are available in several high-technology industries, including nuclear fission

  17. Tritium monitoring : present status

    International Nuclear Information System (INIS)

    Rathnakaran, M.; Singh, A.N.

    1993-01-01

    The report summarizes the present status of techniques employed for the monitoring of tritium in water, air and other samples. A brief mention of the work done by numerous workers in the field, critical comments about the work and a fairly exhaustive list of references about the work done during the last 4 decades has been presented. On-line monitoring on real time basis in nuclear reactors is also discussed. (author). 83 refs., 10 refs., 2 tabs

  18. Status of gluonium searches

    International Nuclear Information System (INIS)

    Heusch, C.A.; California Univ., Santa Cruz, CA

    1991-01-01

    Quantum chromodynamics predicts the existence of quarkless mesons. The search for these hadrons has been ingenious and persevering. A review is presented of the current status of research that considers all model-dependent theoretical prejudice when searching for specific states. Early hints for candidate states have been investigated in the light of recent data, mostly from the Mark III Collaboration, in radiative charmonium decay. No 'smoking-gun' candidate stands out. (R.P.) 25 refs., 20 figs., 2 tabs

  19. Behaviour of fast- and slow growing broilers to 12 weeks of age and the physical consequences

    NARCIS (Netherlands)

    Bokkers, E.A.M.; Koene, P.

    2003-01-01

    Behaviour of broilers up to 6 weeks of age has been studied extensively, but little is known what happens after 6 weeks. Insight in the behavioural abilities after 6 weeks may also yield insight in the period before 6 weeks as the disbalance between motivation and physical abilities is more clearly

  20. Uterine artery Doppler pulsatility index at 11-38 weeks in ICSI pregnancies with egg donation.

    Science.gov (United States)

    Inversetti, Annalisa; Mandia, Luca; Candiani, Massimo; Cetin, Irene; Larcher, Alessandro; Savasi, Valeria; Papaleo, Enrico; Cavoretto, Paolo

    2018-01-26

    Uterine artery Doppler pulsatility index (UtA-PI) may be different in pregnancies with egg donation (ICSI-ED) as compared to conceptions with autologous intra-cytoplasmatic sperm injection (autologous ICSI) and to spontaneous conceptions (SC). One hundred and ninety-four pregnant women with different modes of conception (MC) were prospectively evaluated: 53 ICSI-ED, 36 autologous ICSI and 105 SC. To evaluate the effects of different MC on PI, multivariable linear regression (MLR) models predicting UtA-PI were fitted after adjustment for maternal age, body mass index, race, parity, smoking status and gestational age. In the first trimester, at MLR, autologous ICSI was not associated with a significantly different UtA-PI [estimate (EST) 0.01; 95% confidence interval (CI) -0.19, 0.2; P=0.9] when compared to SC. Conversely, MC by ICSI-ED was associated with lower first trimester UtA-PI (EST -0.32; CI -0.55, -0.08; P=0.01) when compared to SC. At MLR, MC by autologous ICSI and by ICSI-ED were not associated with significant differences in the second and third trimester UtA-PI when compared to SC. ICSI-ED conception presented lower UtA-PI when compared to SC at 11+0-13+6 weeks but not at later assessments. Correction of UtA-PI measurement specifying the origin of oocyte may be useful in first trimester screening.

  1. Salivary surrogates of plasma nitrite and catecholamines during a 21-week training season in swimmers.

    Directory of Open Access Journals (Sweden)

    Miguel Mauricio Díaz Gómez

    Full Text Available The collection of samples of saliva is noninvasive and straightforward, which turns saliva into an ideal fluid for monitoring the adaptive response to training. Here, we investigated the response of the salivary proteins alpha-amylase (sAA, chromogranin A (sCgA, and the concentration of total protein (sTP as well as salivary nitrite (sNO2 in relation to plasma catecholamines and plasma nitrite (pNO2, respectively. The variation in these markers was compared to the intensity and load of training during a 21-week training season in 12 elite swimmers. Overall, the salivary proteins tracked the concentration of plasma adrenaline and were inversely correlated with the training outcomes. No correlations were observed between sNO2 and pNO2. However, sNO2 correlated positively with the intensity and load of training. We argue that the decrease in sympathetic activity is responsible for the decrease in the concentration of proteins throughout the training season. Furthermore, the increase in nitrite is likely to reflect changes in hemodynamics and regulation of vascular tone. The association of the salivary markers with the training outcomes underlines their potential as noninvasive markers of training status in professional athletes.

  2. Coordination and Convening of the 2016 Arctic Science Summit Week

    Energy Technology Data Exchange (ETDEWEB)

    Hinzman, Larry D. [Univ. of Alaska, Fairbanks, AK (United States)

    2016-11-13

    The Arctic Science Summit Week, Arctic Observing Summit, Arctic Council Senior Arctic Officials, Model Arctic Council, and International Arctic Assembly were convened on the campus of the University of Alaska Fairbanks with great productivity and satisfaction of the participants. We were pleased to welcome over 1000 participants from 30 different nations and over 130 different institutions. The organization and execution of these meetings was extensive and complex involving more than 250 coordinators, volunteers and contributors from across Alaska. The participants were enthusiastic in their praise of the content and accomplishments of the meeting, but they were equally happy about the genuine welcome offered to our guests by the people of Alaska. Hosting a complex event such as this summit required an army of supporting services and we were blessed to have volunteers from Fairbanks, North Pole, Anchorage and other communities throughout Alaska helping us meet these needs. This truly was an event hosted by the people of Alaska. The significance of these events cannot be overstated. The US and global communities are finally coming to the realization of the important role that the Arctic plays in international politics, economics, and science. The Arctic has experienced tremendous changes in recent years, offering new opportunities that may be addressed through international collaborations, and serious challenges that must be addressed through active investment, adaptation and national and international coordination. Over 10% of the meeting participants were indigenous peoples, from indigenous organizations or hailed from small remote communities. This is still lower than we had hoped, but it is greater participation than similar meetings have experienced in the past. It is through such engagement that we can attack problems related to the changing environment, stagnant economies, and social ills.

  3. Mental Representations of Social Status

    Science.gov (United States)

    Chiao, Joan Y.; Bordeaux, Andrew R.; Ambady, Nalni

    2004-01-01

    How do people think about social status? We investigated the nature of social status and number representations using a semantic distance latency test. In Study 1, 21 college students compared words connoting different social status as well as numbers, which served as a control task. Participants were faster at comparing occupations and numbers…

  4. Health status of hostel dwellers

    African Journals Online (AJOL)

    Assessment of nutritional status provides an inexpensive, quick and objective measure of the health status of children.I The nutritional status of children (0 - 5 years) in the Zones, an urban migrant hostel complex in Langa outside Cape Town,. Department of Social Anthropology, University of Cape. Town. M. A. RAMPHELE ...

  5. High rate of improvement in serum matrix metalloproteinase-3 levels at 4 weeks predicts remission at 52 weeks in RA patients treated with adalimumab.

    Science.gov (United States)

    Hattori, Yosuke; Kojima, Toshihisa; Kaneko, Atsushi; Kida, Daihei; Hirano, Yuji; Fujibayashi, Takayoshi; Yabe, Yuichiro; Oguchi, Takeshi; Kanayama, Yasuhide; Miyake, Hiroyuki; Kato, Takefumi; Takagi, Hideki; Hayashi, Masatoshi; Ito, Takayasu; Shioura, Tomone; Takahashi, Nobunori; Ishikawa, Hisato; Funahashi, Koji; Ishiguro, Naoki

    2018-01-01

    This study aimed to determine whether serum matrix metalloproteinase-3 (MMP-3) levels can predict remission in rheumatoid arthritis (RA) patients treated with adalimumab (ADA). Subjects were 114 RA patients continuously treated with ADA for 52 weeks. Predictive factors at baseline and 4 weeks after initiation of ADA therapy for the achievement of remission (28-point count Disease Activity Score-CRP (DAS28-CRP) < 2.3) at 52 weeks were evaluated by multivariate logistic regression analysis. DAS28-CRP at 4 weeks (odds ratio (OR) 0.614, 95% confidence interval (CI) 0.382-0.988) and improvement in serum MMP-3 levels at 4 weeks (OR 1.057, 95% CI 1.002-1.032) were independent predictors of remission at 52 weeks. The best cut-off level of DAS28-CRP and improvement in serum MMP-3 levels at 4 weeks for predicting remission at 52 weeks was 3.73 (sensitivity: 90%, specificity: 50%, area under the receiver operating characteristic curve (AUC): 62%) and 39.93% (sensitivity: 47%, specificity: 83%, AUC: 64%), respectively. Our findings suggest that a high rate of improvement in serum MMP-3 levels at 4 weeks after initiation of ADA therapy can predict remission at 52 weeks in RA patients.

  6. Clinical Application of Revised Laboratory Classification Criteria for Antiphospholipid Antibody Syndrome: Is the Follow-Up Interval of 12 Weeks Instead of 6 Weeks Significantly Useful?

    Directory of Open Access Journals (Sweden)

    Sang Hyuk Park

    2016-01-01

    Full Text Available Background. According to revised classification criteria of true antiphospholipid antibody syndrome, at least one of three antiphospholipid antibodies should be present on two or more occasions at least 12 weeks apart. However, it can be inconvenient to perform follow-up tests with interval of 12 weeks. We investigated clinical application of follow-up tests with interval of 12 weeks. Method. Totals of 67, 199, and 332 patients tested positive initially for the lupus anticoagulants confirm, the anti-β2 glycoprotein-I antibody, and the anti-cardiolipin antibody test, respectively, from Jan 2007 to Jul 2009. We investigated clinical symptoms of patients, follow-up interval, and results of each test. Results. Among patients with initial test positive, 1.5%–8.5% were subjected to follow-up tests at interval of more than 12 weeks. Among 25 patients with negative conversion in tests, patients with interval of more than 12 weeks showed clinical symptom positivity of 33.3%, which was higher than that of 12.5% with 6–12 weeks. Among 34 patients with persistent test positive, clinical symptoms positivity trended to be more evident in patients at interval of 6–12 weeks (47.4% versus 26.7%, P=0.191 than more than 12 weeks. Conclusion. Less than 10% of patients with initial test positive had follow-up tests at interval of more than 12 weeks and the patients with persistent test positive at interval of more than 12 weeks showed trends toward having lower clinical symptoms than 6–12 weeks. More research is needed focused on the evidence that follow-up test at interval of more than 12 weeks should be performed instead of 6 weeks.

  7. Eight weeks of exercise training increases aerobic capacity and muscle mass and reduces fatigue in patients with cirrhosis.

    Science.gov (United States)

    Zenith, Laura; Meena, Neha; Ramadi, Ailar; Yavari, Milad; Harvey, Andrea; Carbonneau, Michelle; Ma, Mang; Abraldes, Juan G; Paterson, Ian; Haykowsky, Mark J; Tandon, Puneeta

    2014-11-01

    Patients with cirrhosis have reduced exercise tolerance, measured objectively as decreased peak exercise oxygen uptake (peak VO2). Reduced peak VO2 is associated with decreased survival time. The effect of aerobic exercise training on peak VO2 has not been well studied in patients with cirrhosis. We evaluated the safety and efficacy of 8 weeks of supervised exercise on peak VO2, quadriceps muscle thickness, and quality of life. In a prospective pilot study, stable patients (79% male, 57.6 ± 6.7 years old) with Child-Pugh class A or B cirrhosis (mean Model for End-Stage Liver Disease score, 10 ± 2.2) were randomly assigned to groups that received exercise training (n = 9) or usual care (controls, n = 10) at the University of Alberta Hospital in Canada from February through June 2013. Supervised exercise was performed on a cycle ergometer 3 days/week for 8 weeks at 60%-80% of baseline peak VO2. Peak VO2, quadriceps muscle thickness (measured by ultrasound), thigh circumference, answers from Chronic Liver Disease Questionnaires, EQ-visual analogue scales, 6-minute walk distance, and Model for End-Stage Liver Disease scores were evaluated at baseline and at week 8. Analysis of covariance was used to compare variables. At week 8, peak VO2 was 5.3 mL/kg/min higher in the exercise group compared with controls (95% confidence interval, 2.9-7.8; P = .001). Thigh circumference (P = .001), thigh muscle thickness (P = .01), and EQ-visual analogue scale determined self-perceived health status (P = .01) was also significantly higher in the exercise group compared with controls at week 8; fatigue subscores of the Chronic Liver Disease Questionnaires were lower in the exercise group compared with controls (P = .01). No adverse events occurred during cardiopulmonary exercise testing or training. In a controlled prospective pilot trial, 8 weeks of supervised aerobic exercise training increased peak VO2 and muscle mass and reduced fatigue in patients with cirrhosis. No

  8. The role of radiography in primary care patients with low back pain of at least 6 weeks duration. A randomised (unblinded) controlled trial

    International Nuclear Information System (INIS)

    Kendrick, D.; Fielding, K.; Bentley, E.; Miller, P.; Kerslake, R.; Pringle, M.

    2001-01-01

    Lumbar spine radiography in primary care patients with low back pain of at least 6 weeks duration is not associated with improved functioning, severity of pain or overall health status, and is associated with an increase in GP workload. Participants receiving X-rays are more satisfied with their care, but are not less worried or more reassured about serious disease causing their low back pain

  9. Status of APE projects

    CERN Document Server

    Alfieri, R; Onofri, E; Bartoloni, A; Battista, C; Cabibbo, Nicola; Cosimi, M; Lonardo, A; Michelotti, A; Proietti, B; Rapuano, F; Rossetti, D; Sacco, G; Tassa, S; Torelli, M; Vicini, P; Pène, O; Errico, W; Magazzù, G; Sartori, L; Schiiano, F; Tripiccione, R; De Riso, P; Petronzio, Roberto; Destri, C; Frezzotti, R; Marchesini, G; Gensch, Ulrich; Jansen, K; Kretzschmann, A; Leich, H; Paschedag, N; Pleiter, D; Schwendicke, U; Simma, H; Sommer, Rainer; Sulanke, K; Wegner, P; Fucci, A; Martin, B; Pech, J; Panizzi, E; Petricola, A

    2001-01-01

    This talk is divided in two parts. In the first part, we will summarize the status of the APEmille project that will be completed by the end of the year. We will then devote the rest of the talk to the description of a new project for a multi-TeraFlop machine, ape NEXT. The interested reader will find a much more detailed discussion of all the items touched upon here in the full proposal of the project that will shortly appear on hep-lat. (9 refs).

  10. Model Validation Status Review

    International Nuclear Information System (INIS)

    E.L. Hardin

    2001-01-01

    The primary objective for the Model Validation Status Review was to perform a one-time evaluation of model validation associated with the analysis/model reports (AMRs) containing model input to total-system performance assessment (TSPA) for the Yucca Mountain site recommendation (SR). This review was performed in response to Corrective Action Request BSC-01-C-01 (Clark 2001, Krisha 2001) pursuant to Quality Assurance review findings of an adverse trend in model validation deficiency. The review findings in this report provide the following information which defines the extent of model validation deficiency and the corrective action needed: (1) AMRs that contain or support models are identified, and conversely, for each model the supporting documentation is identified. (2) The use for each model is determined based on whether the output is used directly for TSPA-SR, or for screening (exclusion) of features, events, and processes (FEPs), and the nature of the model output. (3) Two approaches are used to evaluate the extent to which the validation for each model is compliant with AP-3.10Q (Analyses and Models). The approaches differ in regard to whether model validation is achieved within individual AMRs as originally intended, or whether model validation could be readily achieved by incorporating information from other sources. (4) Recommendations are presented for changes to the AMRs, and additional model development activities or data collection, that will remedy model validation review findings, in support of licensing activities. The Model Validation Status Review emphasized those AMRs that support TSPA-SR (CRWMS M and O 2000bl and 2000bm). A series of workshops and teleconferences was held to discuss and integrate the review findings. The review encompassed 125 AMRs (Table 1) plus certain other supporting documents and data needed to assess model validity. The AMRs were grouped in 21 model areas representing the modeling of processes affecting the natural and

  11. Model Validation Status Review

    Energy Technology Data Exchange (ETDEWEB)

    E.L. Hardin

    2001-11-28

    The primary objective for the Model Validation Status Review was to perform a one-time evaluation of model validation associated with the analysis/model reports (AMRs) containing model input to total-system performance assessment (TSPA) for the Yucca Mountain site recommendation (SR). This review was performed in response to Corrective Action Request BSC-01-C-01 (Clark 2001, Krisha 2001) pursuant to Quality Assurance review findings of an adverse trend in model validation deficiency. The review findings in this report provide the following information which defines the extent of model validation deficiency and the corrective action needed: (1) AMRs that contain or support models are identified, and conversely, for each model the supporting documentation is identified. (2) The use for each model is determined based on whether the output is used directly for TSPA-SR, or for screening (exclusion) of features, events, and processes (FEPs), and the nature of the model output. (3) Two approaches are used to evaluate the extent to which the validation for each model is compliant with AP-3.10Q (Analyses and Models). The approaches differ in regard to whether model validation is achieved within individual AMRs as originally intended, or whether model validation could be readily achieved by incorporating information from other sources. (4) Recommendations are presented for changes to the AMRs, and additional model development activities or data collection, that will remedy model validation review findings, in support of licensing activities. The Model Validation Status Review emphasized those AMRs that support TSPA-SR (CRWMS M&O 2000bl and 2000bm). A series of workshops and teleconferences was held to discuss and integrate the review findings. The review encompassed 125 AMRs (Table 1) plus certain other supporting documents and data needed to assess model validity. The AMRs were grouped in 21 model areas representing the modeling of processes affecting the natural and

  12. Status of Wheeler Reservoir

    Energy Technology Data Exchange (ETDEWEB)

    1990-09-01

    This is one in a series of status reports prepared by the Tennessee Valley Authority (TVA) for those interested in the conditions of TVA reservoirs. This overview of Wheeler Reservoir summarizes reservoir purposes and operation, reservoir and watershed characteristics, reservoir uses and use impairments, and water quality and aquatic biological conditions. The information presented here is from the most recent reports, publications, and original data available. If no recent data were available, historical data were summarized. If data were completely lacking, environmental professionals with special knowledge of the resource were interviewed. 12 refs., 2 figs.

  13. NESTOR: A status report

    CERN Document Server

    Anassontzis, E G; Barone, M; Foudas, C; Grammatikakis, G; Katsanevas, S; Kourkoumelis, C; Manousakis-Katsikakis, A; Resvanis, L K; Siotis, I; Sotiriou, S A; Voulgaris, G; Minkowski, P; Grieder, P K F; Ball, A E; Bottai, S; Cartacci, A M; Monteleoni, B; Naumov, Vadim A; Trasatti, L; Fahrun, E; Keusen, U; Koske, P; Rathlev, J; Schmidt, N P; Voight, G; Bezrukov, Leonid B; Butkevich, A V; Dedenko, L G; Karaevsky, S K; Mironovich, A A; Zakharov, L M; Zheleznykh, I M; Zhukov, V A; Demidova, T A; Deineko, A O; Eremeev, A P; Paka, V T; Permyakov, A A; Platonov, M N; Rukol, V Kh; Sheremet, N A; Surin, N M; Albul, V I; Ledenev, V V

    2000-01-01

    NESTOR is an underwater neutrino astrophysics laboratory to be located in the international waters of the southwest of Greece. The first phase of this experiment is the construction and deployment of one hexagonal tower consisting of 168 optical modules, with effective are of 20000m2 for E ⩾ TeV neutrinos. Over the past few years detailed studies of the site have been carried out while many tests have been performed. The current status of the preparation of the experiment and the future plans will be presented.

  14. The status of molecules

    International Nuclear Information System (INIS)

    Barnes, T.

    1994-01-01

    The experimental and theoretical status of hadronic molecules, which are weakly-bound states of two or more hadrons are summarized. A brief history of the subject is given, and a few good candidates are discussed. Some signatures for molecules which may be of interest in the classification of possible molecule states are studied. It is shown that a more general understanding of 2 → 2 hadron-hadron scattering amplitudes will be crucial for molecule searches. A few more recent molecule candidates which are not well established as molecules but satisfy some of the expected signatures are also discussed. (author). 50 refs

  15. Teleradiology - current status

    International Nuclear Information System (INIS)

    Baltadjiev, D.; Charakchiev

    2000-01-01

    Tele-radiology is a term becoming increasingly popular in the medical literature. Nevertheless, terminological definitions in this particular field are still rather vague. The scope of applications extend from simple image presenting via analogue telephone lines to transmission of 3-D medical images through a satellite. It is a matter of standards highly differing in terms of data transmission rates, safety, technical demands on the systems and the like. In this article new information technologies, technical aspects, as well as some major applications of tele-radiology are discussed. The current status of tele-medicine/tele-radiology in this country is likewise briefly outlined

  16. 1998 status report

    International Nuclear Information System (INIS)

    1998-01-01

    Since its creation in 1945, the activities of Cea have been centered on the study and development of the pacific use of nuclear energy and on assuring the credibility of nuclear deterrent. This status report presents the research programs led by Cea in 1998. The main topics are: the designing of reactor cores, fuel cycle, nuclear safety, radiation protection, the activities for defense, high technologies for industry, biology and fundamental sciences. The quality of research work is assured by an independent and regular assessment of the scientific activities. (A.C.)

  17. Discrepancy between exercise performance, body composition, and sex steroid response after a six-week detraining period in professional soccer players.

    Science.gov (United States)

    Koundourakis, Nikolaos E; Androulakis, Nikolaos E; Malliaraki, Niki; Tsatsanis, Christos; Venihaki, Maria; Margioris, Andrew N

    2014-01-01

    The aim of this study was to examine the effects of a six-week off-season detraining period on exercise performance, body composition, and on circulating sex steroid levels in soccer players. Fifty-five professional male soccer players, members of two Greek Superleague Teams (Team A, n = 23; Team B, n = 22), participated in the study. The first two weeks of the detraining period the players abstained from any physical activity. The following four weeks, players performed low-intensity (50%-60% of VO2max) aerobic running of 20 to 30 minutes duration three times per week. Exercise performance testing, anthropometry, and blood sampling were performed before and after the six-week experimental period. Our data showed that in both teams A and B the six-week detraining period resulted in significant reductions in maximal oxygen consumption (60,31±2,52 vs 57,67±2,54; pperiod resulted in a rapid loss of exercise performance adaptations and optimal body composition status, but did not affect sex steroid resting levels. The insignificant changes in sex steroid concentration indicate that these hormones were a non-contributing parameter for the observed negative effects of detraining on exercise performance and body composition.

  18. A 24-week dietary and physical activity lifestyle intervention reduces hepatic insulin resistance in the obese with chronic hepatitis C.

    Science.gov (United States)

    Pattullo, Venessa; Duarte-Rojo, Andres; Soliman, Wael; Vargas-Vorackova, Florencia; Sockalingam, Sanjeev; Fantus, Ivan G; Allard, Johane; Heathcote, Jenny

    2013-03-01

    Obesity- and virus-mediated insulin resistance (IR) are associated with adverse hepatic and metabolic outcomes in chronic hepatitis C (CHC). This study evaluates the tolerability and effects of a dietary and physical activity (PA) intervention in obese patients with insulin-resistant CHC. Obese patients (body mass index, BMI ≥30 kg/m(2) ) with CHC were recruited prospectively. Non-diabetic patients with IR (homeostasis model assessment of IR, HOMA-IR >2.0) proceeded to a 24-week lifestyle intervention comprising pedometer monitored increase in PA (≥10 000 steps/day) and an individualised dietary plan. Ten non-cirrhotic and six cirrhotic patients [age 52 ± 8.5 years, BMI 35.9 (31.46-38.21)kg/m(2) ] were recruited, of whom all 16 (100%) completed the 24-week protocol. Increase in PA from 6853 (2440-9533) to 10 697 (7959-13566) steps/day (P = 0.001) and reduction in caloric intake from 2263 (1805.4-2697.0) to 1281 (1099.5-1856.3) kcal/day (equivalent to reduction of median 33% (25.3-49.8%), P insulin sensitivity index (ISI) improved significantly, but the skeletal muscle ISI did not. At week 24, 8/16 (50%) patients were no longer insulin-resistant (P = 0.008). This 24-week intervention reduced BMI and reversed IR in significant proportion of patients. Such adjunctive therapy may improve hepatic and metabolic status in obese insulin-resistant CHC. © 2012 John Wiley & Sons A/S.

  19. The effect of 12-weeks concurent training on the serum levels NGF, BDNF, and VDBP in women with multiple sclerosis

    Directory of Open Access Journals (Sweden)

    Mitra Khademosharie

    2018-03-01

    Full Text Available Recent studies suggest that patients with multiple sclerosis(MS have low levels of neurotrophic factors such as nerve growth factor(NGF, brain-derived neurothrophic factor(BDNF and the vitamin D-binding protein(VDBP, and exercise training may affects these factors in people with MS. The purpose of this study was to investigate the effect of a combined exercise training programon the serum levels of neurotrophic factos in women with MS. A randomized controlled clinical trial was conducted in 24 volunteer MS patients(Expanded Disability Status Scale range of 1–5. Resting serum levels of BDNF, NGF, VDBP, body composition variables, and disability scale values were determined before and  after the intervention. The intervention consisted of  three sessions of combined training a week for 12 weeks(two sessions of aerobic and one session of resistance training, progressively. Aerobic training consisted of interval training with 4-13 repetition of aerobic activity at 40-55% of heart rate reserve; and resistance training consisted of 8-12 repetitions with 60-80% of 1RM for eight movements. The results showed a significant decrease in body fat percentage (p=0.003 and disability scale value(p=0.007 in the experimental group. no other significant changes was observed for other variables or in the control group. This study indicates that although the combined aerobic and resistance training in three non-consecutive days per week for 12 weeks has no effect on NGF, BDNF, and VDBP; however with positive effects on the body fat percentage and disability scale value can be for women with MS.

  20. Effects of induction of labour versus expectant management in women with impending post-term pregnancies: the 41 week - 42 week dilemma.

    Science.gov (United States)

    Kortekaas, Joep C; Bruinsma, Aafke; Keulen, Judit K J; van Dillen, Jeroen; Oudijk, Martijn A; Zwart, Joost J; Bakker, Jannet J H; de Bont, Dokie; Nieuwenhuijze, Marianne; Offerhaus, Pien M; van Kaam, Anton H; Vandenbussche, Frank; Mol, Ben Willem J; de Miranda, Esteriek

    2014-10-23

    Post-term pregnancy, a pregnancy exceeding 294 days or 42 completed weeks, is associated with increased perinatal morbidity and mortality and is considered a high-risk condition which requires specialist surveillance and induction of labour. However, there is uncertainty on the policy concerning the timing of induction for post-term pregnancy or impending post-term pregnancy, leading to practice variation between caregivers. Previous studies on induction at or beyond 41 weeks versus expectant management showed different results on perinatal outcome though conclusions in meta-analyses show a preference for induction at 41 weeks. However, interpretation of the results is hampered by the limited sample size of most trials and the heterogeneity in design. Most control groups had a policy of awaiting spontaneous onset of labour that went far beyond 42 weeks, which does not reflect usual care in The Netherlands where induction of labour at 42 weeks is the regular policy. Thus leaving the question unanswered if induction at 41 weeks results in better perinatal outcomes than expectant management until 42 weeks. In this study we compare a policy of labour induction at 41 + 0/+1 weeks with a policy of expectant management until 42 weeks in obstetrical low risk women without contra-indications for expectant management until 42 weeks and a singleton pregnancy in cephalic position. We will perform a multicenter randomised controlled clinical trial. Our primary outcome will be a composite outcome of perinatal mortality and neonatal morbidity. Secondary outcomes will be maternal outcomes as mode of delivery (operative vaginal delivery and Caesarean section), need for analgesia and postpartum haemorrhage (≥1000 ml). Maternal preferences, satisfaction, wellbeing, pain and anxiety will be assessed alongside the trial. This study will provide evidence for the management of pregnant women reaching a gestational age of 41 weeks. Dutch Trial Register (Nederlands Trial Register): NTR

  1. Age, relationship status, and the planning status of births

    Directory of Open Access Journals (Sweden)

    Sarah Hayford

    2010-08-01

    Full Text Available In the United States historically, births to older mothers have been more likely to be planned than births to younger mothers, and births to unmarried women have been less likely to be planned than births to married women. As the average age of mothers has increased and more births have occurred outside of marriage in the United States, the intersection of these trends may have weakened the traditional linkage between age and birth planning status. In this article, we examine differences by maternal age in planning status of births using The 2002 National Survey of Family Growth. We find that age is strongly associated with planning status, but the association is reduced in magnitude when controlling for relationship status and is stronger for first and second births than for higher-parity births. Further, the association between union status and the planning status of births varies by race-ethnicity.

  2. ANAEMIA ERADICATION IN ADOLESCENTS- A NEW HOPE WITH WEEKLY IRON FOLIC ACID SUPPLEMENTATION (WIFS (PILOT STUDY

    Directory of Open Access Journals (Sweden)

    Hema Divakar

    2017-02-01

    Full Text Available BACKGROUND Anaemia is perceived to be a major public health problem especially among adolescent females .Findings from National Family Health Survey NFHS (2005-06 indicate that 56% of the adolescent girls in India are anaemic and, of these 17% suffer from moderate to severe anaemia. The prevalence of anaemia in female adolescent age group is still an understudied subject. The aims of this study were to evaluate the recently initiated WIFS program for government school girls with respect to implementation and impact on trends in prevalence of Anaemia among adolescent girls in a Bengaluru rural school. MATERIALS AND METHODS Cross-sectional, descriptive exploratory research study was used. The choice of the school was based on commitment to administration of weekly iron-folic acid supplements (WIFS programme. All the girl students from class 6 th to 10th of Government High and Senior Secondary school (age group, 11-19 years who were a part of WIFS were enrolled as study participants. Qualitative data on anaemia awareness and diet history, compliance, side effects were taken from these girls. General information on age, height, weight were collected and BMI calculated. Hb estimation was done by Haemocue method. Statistical Analysis- Analysis were prepared by IBM SPSS Statistics version 22. RESULTS Out of the 95girls in the school, there were 81 girls (85.26% reported to consume one tablet of Iron folic acid (IFA weekly in the past 1 year, with no major side effects. The girls had knowledge about symptoms of anaemia and iron-rich diet. Hb estimates indicated 79.01% non anaemic, prevalence of anaemia was 20.99%; none of the girls had severe anaemia, 1.2% had moderate anaemia and the remaining 19.8% belonged to mild anaemia category, indicating a significant decline. The mean BMI of the study sample was 17.53 kg/m2 with 67.9% underweight and 6.2% overweight. CONCLUSION Overall, in this school, the WIFS program was found to be well implemented with good

  3. The effect of grape-skin extract on oxidative status

    DEFF Research Database (Denmark)

    Young, J. F.; Dragsted, L. O.; Daneshvar, B.

    2000-01-01

    Epidemiological studies indicate that moderate alcohol consumption, particularly wine, reduce the risk of CHD. The present study was designed to investigate the effect of grape-skin extract on markers of oxidative status. The study was designed as a randomised crossover. A diet with a low content...... of flavonoids was served with strict control of intake in two consecutive 1-week intervention periods to fifteen subjects (nine women, six men) divided randomly into two groups. During one of the weeks the subjects from either group consumed 200 ml grape-skin extract in water (1 mg extract/ml) at each of three....... Intake of the experimental diet significantly reduced plasma vitamin C and plasma AAS in both groups. This effect was most pronounced in the particular week with no grape-skin extract addition. We speculate that grape-skin extract may have a sparing effect on vitamin C. The effects of the experimental...

  4. Who coined the term “status gelasticus”? We did

    Directory of Open Access Journals (Sweden)

    Yu-tze Ng

    2009-07-01

    Full Text Available Yu-tze NgDivision of Pediatric Neurology, Barrow Neurological Institute, Phoenix, AZ, USAIn a recent review article on gelastic seizures and hypothalamic hamartoma, Tellez-Zenteno and colleagues used the term, “status gelasticus” mostly correctly but referenced completely incorrectly the origins of the definition of this rare but becoming increasingly known phenomenon. This mistake followed upon an unusual oversight of quoting another author who had simply used the term and most certainly did not make any attempts to define it. We had initially published a case report of a 30-month-old boy who underwent successful emergent transcallosal resection of his hypothalamic hamartoma for status gelasticus which lasted six weeks!3 In this report, we made clear mention that we labeled his “history of near-continuous gelastic seizures” as status gelasticus.

  5. Epidemiological and virological situation update of the 2010/2011 influenza season in the WHO European Region (Week 40/2010 to Week 03/2011)

    NARCIS (Netherlands)

    Mott, J.A.; Pereyaslov, D.; Jorgensen, P.; Brown, C.S.; Martirosyan, L.; Meerhoff, T.

    2011-01-01

    This overview of influenza data from the WHO European Region from weeks 40/2010 through week 3/2011 has been submitted for consideration during the WHO Northern Hemisphere Vaccine Strain Selection Meeting, to be held on 14-17 February, 2011, in Geneva. The 2010/2011 influenza season arrived 8-10

  6. Dose intensity comparison between weekly and 3-weekly Cisplatin delivered concurrently with radical radiotherapy for head and neck cancer: A retrospective comparison from New Cross Hospital, Wolverhampton, UK

    International Nuclear Information System (INIS)

    Ho, Kean F.; Brammer, Caroline V.; Swindell, Ric

    2008-01-01

    Aims. In this retrospective comparison, we describe the differences in dose intensity, delays and toxicity between weekly Cisplatin and 3-weekly Cisplatin given concurrently to patients with locally advanced squamous head and neck cancer (SCCHN) at New Cross Hospital, Wolverhampton. Materials and methods. Fifty-one patients received radical Cisplatin based chemoradiotherapy for stage 4a SCCHN of the head and neck between September 2000 and December 2004. Twenty-seven patients were treated with 3-weekly inpatient Cisplatin for 3 cycles (20 patients-80 mg/m 2 ; 7 patients-100 mg/m 2 ) concomitantly with radiotherapy (66-70 Gy/33-35 fractions). Twenty-four patients received a similar radiotherapy schedule but received weekly Cisplatin 33-40 mg/m 2 . Results. More patients received a higher cumulative dose of at least 240 mg/m 2 if given weekly Cisplatin 40 mg/m 2 or 3-weekly Cisplatin 80 mg/m 2 compared with those receiving Cisplatin 3-weekly 100 mg/m 2 (p=0.04). Maximum cumulative dose achievable in the latter group was only 200 mg/m 2 and none achieved the full 3 cycles. Mean Cisplatin dose in the weekly Cisplatin 40 mg/m 2 regime (mean 202 mg/m 2 ) and 3-weekly arm of 80 mg/m 2 (mean 203 mg/m 2 ) was higher than that reached if given 3-weekly Cisplatin 100 mg/m 2 (mean 180 mg/m 2 ) although statistically insignificant (p=0.39) due to the small number of patients. More delays (29% vs. 41%) and omission of chemotherapy (5.6% vs. 17.4%) occurred in the 3-weekly compared with the weekly regime. Toxicity, radiotherapy overall treatment time and delays were similar between the two groups. Conclusion. Delivery of 100 mg/m 2 Cisplatin 3-weekly with radiotherapy was less tolerated than 40 mg/m 2 weekly and resulted in less patients achieving cumulative dose beyond 200 mg/m 2 , potentially lowering chemotherapy dose intensity

  7. The status of molecules

    International Nuclear Information System (INIS)

    Barnes, T.; Oak Ridge National Lab., TN; Tennessee Univ., Knoxville, TN

    1994-06-01

    This report summarizes the experimental and theoretical status of hadronic molecules, which are weakly-bound states of two or more hadrons. We begin with a brief history of the subject and discuss a few good candidates, and then abstract some signatures for molecules which may be of interest in the classification of possible molecule states. Next we argue that a more general understanding of 2 → 2 hadron-hadron scattering amplitudes will be crucial for molecule searches, and discuss some of our recent work in this area. We conclude with a discussion of a few more recent molecule candidates (notably the f o (1710)) which are not well established as molecules but satisfy some of the expected signatures. (Author)

  8. Status report on GANIL

    International Nuclear Information System (INIS)

    Ferme, J.; Gouttefangeas, M.

    1982-01-01

    The parameters of the three accelerators Col, SSC1 and SSC2 of the GANIL system are recalled with a special emphasis on those which have been modified since the beginning of the construction; furthermore consequences of theoretical works which were made in order to obtain a beam with small energy dispersion δW/W are given. The current status of the project is then described: the Col injector is already in operation, as well as the first part of the line L1 (from Col to SSC1) which is used to analyze the beam coming from Col; magnets (with their trim-coils) and chamber (vacuum tested) of SSC1 are completely assembled; routine magnetic measurements are in progress whereas the first resonant accelerating cavity is on a special test bench; magnets and chamber of SSC2 are installed and vacuum tests are under way

  9. Status of Standardization Projects

    Science.gov (United States)

    1991-06-30

    STATUS CODES: A- 1, G- 0, Y- 0, Z- 0 1 1265 A009 MIL C XXX CMPTR SYS GUN CP 1317 GYK 29 CR F4 894 914 914 A N D 1265 AO1O MIL L 70846 LASER TUBE/MOD...ASSY 11749646 AR B4 903 904 904 A N C 1265 A011 NIL L 70847 LASER TUBE/PWB ASSY 11749644 AR B4 903 904 904 A N C 1265 A012 MIL L 70848 LASER TUBE/PWB...VIBRATOR, MOLD MB DM F4 A 881 891 914 A MD MS 03 U D 6520 2102 A-A-XXX STOP, ENDODONTIC MB DM F4 A 892 902 914 A MD MS 03 U D 6520 2104 A-A-XXX

  10. Status of legislation

    International Nuclear Information System (INIS)

    Warner, C.

    1982-01-01

    The status of the House legislation, the major differences between the House and Senate legislation and a preview of what is likely to take place during the lame duck session in December are presented. The House legislation provides: long-term program leading toward permanent disposal of nuclear waste; an interim program for storage and for expansion of storage space for spent fuel; provides an R and D component through what is called a test and evaluation facility; an alternative long-term storage program based on a proposal to be completed by the Department of Energy on what's called Monitored Retrievable Storage; full upfront financing of the program through user fees based on contracts between the government and the users of the nuclear waste disposal services

  11. PANIC: current status

    Science.gov (United States)

    Cárdenas, M. C.; Rodríguez Gómez, J.

    2011-11-01

    PANIC, the PAnoramic Near Infrared Camera, is a new instrument for Calar Alto Observatory (CAHA) is a wide-field infraredimager for the CAHA 2.2 m and 3.5 m telescopes. The optics is a folded single optical train, pure lens optics, with a pixel scale of 0.45 arcsec/pixel (18 microns) at the 2.2 m telescope and 0.23 arcsec/pixel at the 3.5 m. A mosaic of four Hawaii-2RG detectorsprovides a field of view (FOV) of 0.5x0.5 degrees and 0.25x0.25 degrees, respectively. It will cover the photometric bandsfrom Z to K_s (0.8 to 2.5 microns) with a low thermal background due to cold stops. Here we present the current status of the project.

  12. Orion Project Status Report

    Science.gov (United States)

    Stiewing, Albert; Hopkins, Jeffrey L.

    2015-05-01

    Originally started in 2012 as the Betelgeuse Project, interest in the other bright stars of Orion soon expanded the Project stars to include a total of six of the brightest stars in Orion. The name was then changed to the Orion Project. Orion is one of the most famous constellations. Its declination along the celestial equator is such that it is visible from most of northern and southern hemispheres. In addition, the stars of Orion are very bright and interesting. The Orion Project now includes the stars Betelgeuse, Rigel, Saiph and the three stars of Orion's belt, Mintaka, Alnilam and Alnitak. The projects objectives are both to help the observer produce quality photometric and spectroscopic data and to produce archival quality photometric (BVRIJH bands) and spectroscopy (low, mid and high-resolution) data. This paper is a summary of the Orion Project status.

  13. ARAC status report: 1985

    International Nuclear Information System (INIS)

    Dickerson, M.H.; Gudiksen, P.H.; Sullivan, T.J.; Greenly, G.D.

    1985-05-01

    The Atmospheric Release Advisory Capability is a real-time emergency-response service available to federal and state agencies for providing estimates of the environmental consequences of accidental releases of radioactivity into the atmosphere. This includes the estimation of radiation doses to nearby population centers and the levels and extent of surface contamination. The service is currently being expanded to support the emergency response plans at approximately 50 Department of Defense and Department of Energy facilities. This expansion consists of the installation of enhanced computational and data communications and processing systems, development of terrain and geographic data bases, improvements in modeling capabilities, as well as increased staff housing facilities. This report summarizes the current status of ARAC and the requirements to receive the service

  14. The CMS HF status

    CERN Document Server

    Rahmat, Rahmat

    2012-01-01

    The experiments at the Large Hadron Collider will have to deal with unprecedented radiation levels. The design of the CMS forward calorimetry detector (HF) is now finalized. The present design of CMS calls for the HF calorimeter to be based on quartz fiber technology. It consists of two modules, located symmetrically at about 11 meters from either side of interaction point. They cover the pseudorapidity range 3-5. The length along the beam is 1.65m or 10 nuclear interaction lenghts. Each calorimeter consists of a large steel block that serves as the absorber. Embedded quartz fibers in the steel absorber run parallel to the beam and constitute the active component of the detector. In order to optimize energy resolution for E and ET flows and forward jets, the calorimeter is effectively segmented longitudinally by using two different fiber lengths. The present status will be discussed.

  15. Status of Standardization Projects

    Science.gov (United States)

    1994-06-30

    DELINQUENT - I , STATUS CODES: A- 2 , G- 0 , Y - 0 . Z- 0 1650 0514 MIL-C-5500D CAP HIGH PRESSURE AIR VALUE 71 C2 934 954 954 A AV AS 99 N 1650 0515...AS 85 N 5920 A179 NIL A 49201 ARRESTER ELEC F1482 F1495 G CR 02 904 924 934 A CR U B 5920 A947 NIL M 49240A MULTIPLEXER TO 1235 P TTC CR Fl 923 924...ANESTHESIA SET MB H5 942 952 943 G MD MS 03 U 6515 5706 A-A-XXX TUBE INHALER MB DM F4 A 942 952 952 A MD MS 03 N 6515 5707 A-A-XXX TUBES, DRAINAGE MB DM

  16. Status of Standardization Projects

    Science.gov (United States)

    1992-12-31

    Z- 0 3770 0136 MIL-C-1161E 1 COLLAR DOG LEATHER 84 CS Fl 921 931 931 Y GL 99 U 3770 0138 MIL C 43390C CLIPPER HAIR & BLADE MB OM H5 922 932 924 G MD...OM H5 923 933 933 A MD MS 03 MB N 6505 5782 A-A-XXX METHYLPHENIDATE MB DM F4 A 923 933 931 G MD MS 03 MB U *6505 5783 A-A-XXX QUINIDlNE SULFATE MB OH...A MR AS 99 U B IS TOTAL- 244, DELNQT- 199. STATUS CODES: A- 241, G- 3, Y- 0, Z- 0 3770 0138 MIL C 43390C CLIPPER HAIR & BLADE MB DM H5 922 932 924 G

  17. Media Challenging Status Quo

    DEFF Research Database (Denmark)

    Sandvik, Kjetil

    and Libya creating headlines like “the Facebook revolution”. On the other hand, several scholars argue that it is naive to believe that social media in themselves create change: they may at the best facilitate already existing social and political movements (Downing 2008, Christakis & Fowler 2010...... and dystopian trends in contemporary culture (Turner 2006). On that note, this paper examines the Occupy Wall Street-movement as an example on how social media may rock the status quo of today’s global power structures putting to use its democratic potential and its modes of communication through network...... power of social network and how they shape our lives, New York, Boston and London: Backbay Books/Little, Brown and Company Downing, J. (2008). ”Social Movement Theories and Alternative Media: An Evaluation and Critique”, in: ICA: Communication, Culture & Critique 1 Morozov, J. (2011). The Net Delusion...

  18. Status of French reactors

    International Nuclear Information System (INIS)

    Ballagny, A.

    1997-01-01

    The status of French reactors is reviewed. The ORPHEE and RHF reactors can not be operated with a LEU fuel which would be limited to 4.8 g U/cm 3 . The OSIRIS reactor has already been converted to LEU. It will use U 3 Si 2 as soon as its present stock of UO 2 fuel is used up, at the end of 1994. The decision to close down the SILOE reactor in the near future is not propitious for the start of a conversion process. The REX 2000 reactor, which is expected to be commissioned in 2005, will use LEU (except if the fast neutrons core option is selected). Concerning the end of the HEU fuel cycle, the best option is reprocessing followed by conversion of the reprocessed uranium to LEU

  19. Biomarkers of Selenium Status

    Directory of Open Access Journals (Sweden)

    Gerald F. Combs, Jr.

    2015-03-01

    Full Text Available The essential trace element, selenium (Se, has multiple biological activities, which depend on the level of Se intake. Relatively low Se intakes determine the expression of selenoenzymes in which it serves as an essential constituent. Higher intakes have been shown to have anti-tumorigenic potential; and very high Se intakes can produce adverse effects. This hierarchy of biological activities calls for biomarkers informative at different levels of Se exposure. Some Se-biomarkers, such as the selenoproteins and particularly GPX3 and SEPP1, provide information about function directly and are of value in identifying nutritional Se deficiency and tracking responses of deficient individuals to Se-treatment. They are useful under conditions of Se intake within the range of regulated selenoprotein expression, e.g., for humans <55 μg/day and for animals <20 μg/kg diet. Other Se-biomarkers provide information indirectly through inferences based on Se levels of foods, tissues, urine or feces. They can indicate the likelihood of deficiency or adverse effects, but they do not provide direct evidence of either condition. Their value is in providing information about Se status over a wide range of Se intake, particularly from food forms. There is need for additional Se biomarkers particularly for assessing Se status in non-deficient individuals for whom the prospects of cancer risk reduction and adverse effects risk are the primary health considerations. This would include determining whether supranutritional intakes of Se may be required for maximal selenoprotein expression in immune surveillance cells. It would also include developing methods to determine low molecular weight Se-metabolites, i.e., selenoamino acids and methylated Se-metabolites, which to date have not been detectable in biological specimens. Recent analytical advances using tandem liquid chromatography-mass spectrometry suggest prospects for detecting these metabolites.

  20. Multiple 60-Minute Massages per Week Offer Relief for Chronic Neck Pain

    Science.gov (United States)

    ... Minute Massages per Week Offer Relief for Chronic Neck Pain Share: © Bob Stockfield Courtesy: National Center for Complementary ... fewer or shorter sessions for people with chronic neck pain, suggesting that several hour-long massages per week ...

  1. Northern Hemisphere EASE-Grid 2.0 Weekly Snow Cover and Sea Ice Extent

    Data.gov (United States)

    National Aeronautics and Space Administration — The Northern Hemisphere EASE-Grid 2.0 Weekly Snow Cover and Sea Ice Extent Version 4 product combine snow cover and sea ice extent at weekly intervals from 23...

  2. Gemcitabine and cisplatin in locally advanced and metastatic bladder cancer; 3- or 4-week schedule?

    DEFF Research Database (Denmark)

    Als, Anne Birgitte; Sengeløv, Lisa; Von Der Maase, Hans

    2008-01-01

    -week schedule and comparisons of the feasibility and toxicity between the two schedules have not previously been published. MATERIAL AND METHODS: We performed a retrospective analysis of patients with stage IV TCC, treated with GC by a standard 4-week or by an alternative 3-week schedule. RESULTS......: A total of 212 patients received GC (3-week; n = 151, 4-week; n = 61). We found no statistical differences in overall survival between the two schedules (hazard ratio 1.15, 95% CI 0.83-1.59), p = 0.40). Five-year survival rates were 14.9% and 11.8% for the 3- and 4-week schedule, respectively (p = 0...... intensity for gemcitabine was accordingly lower in the 4 week-schedule. The higher dose intensity of cisplatin in the 3-week schedule, did not lead to increased renal toxicity. In 13 patients with impaired renal function, cisplatin was split into 2 days, which was feasible and efficient. CONCLUSION...

  3. Comparison of self-reported week-day and weekend-day sitting time and weekly time-use: results from the Australian Longitudinal Study on Women's Health.

    Science.gov (United States)

    van Uffelen, Jannique G Z; Watson, Melanie J; Dobson, Annette J; Brown, Wendy J

    2011-09-01

    The study of sedentary behavior is a relatively new area in population health research, and little is known about patterns of sitting time on week-days and weekend-days. To compare self-reported week-day and weekend-day sitting time with reported weekly time spent in other activities. Data were from 8,717 women born between 1973 and 1978 ('younger'), and 10,490 women born between 1946 and 1951 ('mid-age') who completed surveys for the Australian Longitudinal Study on Women's Health in 2003 and 2001, respectively. They were asked about time spent sitting on week-days and weekend-days. The women were also asked to report time spent in employment, active leisure, passive leisure, home duties, and studying. Mean week-day and weekend-day sitting times were compared with time-use using analysis of variance. Younger women sat more than mid-aged women, and sitting time was higher on week-days than on weekend-days in both cohorts. There were marked positive associations between week-day and weekend-day sitting times and time spent in passive leisure in both cohorts, and with time spent studying on week-days for the younger women. Week-day sitting time was markedly higher in women who reported >35 h in employment, compared with those who worked day sitting time was higher than weekend-day sitting time, the patterns of the relationships between week-day and weekend-day sitting and time-use were largely similar, except for time spent in employment.

  4. Weekly lifestyle counselling improves glucose level in type 2 diabetes mellitus patients

    Directory of Open Access Journals (Sweden)

    Amallia Nuggetsiana Setyawati

    2013-08-01

    Full Text Available Introduction Regular physical exercise and healthy life style have been demonstrated to improve health status of a number of populations. In adherence, counselling on life style and dietary nutrition have been one of the investigated methods to determine its effectiveness toward metabolic syndrome predictors. The aim of this study was to evaluate the effect of lifestyle change and dietary counselling on glucose level, body mass index (BMI, waist circumference, blood pressure, total cholesterol, triglycerides, low density lipoprotein (LDL, and high density lipoprotein (HDL in type 2 diabetes mellitus (T2DM patients. Methods A randomized controlled trial was conducted and 26 diagnosed subjects with T2DM were enrolled in the study. After initial screening, they were randomized into the control group and the intervention group, following stratification by gender and age. The intervention group received weekly counselling and education, while the control group received counselling and education only once at the initial meeting. Independent t-test was used to compare the glucose level between the two-groups. Results Lifestyle counselling and dietary modification effected a significant improvement in blood glucose (p=0.002, but not in BMI, waist circumference, total cholesterol, triglycerides, LDL and HDL. In addition, a positive time effect was found in the intervention group before and after treatment on BMI (p=0.009, waist circumference (p=0.0014, and glucose level (p=0.001. The intervention group also showed a significant positive attitude; almost all of the respondents tried to control their food intake and perform exercise regulary. Conclusion Dietary nutrition and lifestyle counselling improve blood glucose control in the short term.

  5. Association Between Dehydration and Fever During the First Week of Life.

    Science.gov (United States)

    Boutin, Ariane; Carceller, Ana; Desjardins, Marie Pier; Sanchez, Marisol; Gravel, Jocelyn

    2017-12-01

    Trying to differentiate serious bacterial infection (SBI) from a self-limiting illness in febrile infants seen in the pediatric emergency department (PED) is a significant challenge. The aim of the study was to determine the prevalence of dehydration and its relationship to SBI in febrile full-term newborns under 1 week of age seen in a PED. A retrospective observational study was carried out on all children younger than 8 days of age with fever who presented to a single, tertiary care, PED from January 2009 to April 2014. Dehydration was defined as plasma sodium >150 mmol/L or >10% loss of birth weight. SBI was defined by the presence of a positive culture in the blood, urine, cerebrospinal fluid; osteoarticular infection; bacterial enteritis; or pneumonia. The primary analysis was the proportion of children with dehydration. A secondary analysis compared proportion of infection according to hydration status. Of the 895 children under 8 days of age who visited the PED, 69 consulted for fever. Seven patients were excluded because they were transferred from another hospital. Sixty-two eligible patients were included in the final analysis. Of these, 17 (27%) were dehydrated according to our definition. Only 2 patients had an SBI while 2 others had a final diagnosis of viral myocarditis and encephalitis, respectively. None of the 4 children with serious infection fulfilled our definition of dehydration, and all had a plasma sodium level lower than 145 mmol/L. Dehydration is frequently associated with fever in infants younger than 8 days of age seen in a PED. Early identification of dehydration may be useful in limiting the aggressive intervention in some of these infants.

  6. 77 FR 21448 - Security Zone; 2012 Fleet Week, Port Everglades, Fort Lauderdale, FL

    Science.gov (United States)

    2012-04-10

    ...-AA87 Security Zone; 2012 Fleet Week, Port Everglades, Fort Lauderdale, FL AGENCY: Coast Guard, DHS... waters of Port Everglades in Fort Lauderdale, Florida during 2012 Fleet Week. 2012 Fleet Week will take... Everglades Harbor. The security zone will be enforced while U.S. Navy vessels participating in 2012 Fleet...

  7. 75 FR 57835 - Constitution Day and Citizenship Day, Constitution Week, 2010

    Science.gov (United States)

    2010-09-22

    ... Part II The President Proclamation 8562--Constitution Day and Citizenship Day, Constitution Week... Constitution Day and Citizenship Day, Constitution Week, 2010 By the President of the United States of America... journey. On Constitution Day and Citizenship Day, and during Constitution Week, we commemorate the legacy...

  8. 75 FR 8563 - Safety Zone; Fleet Week Maritime Festival, Pier 66, Elliott Bay, Seattle, WA

    Science.gov (United States)

    2010-02-25

    ...-AA00 Safety Zone; Fleet Week Maritime Festival, Pier 66, Elliott Bay, Seattle, WA AGENCY: Coast Guard... Fleet Week Maritime Festival. This safety zone is necessary as these events have historically resulted... the safety of life and property on navigable waters during the annual Fleet Week Maritime Festival...

  9. Weekly Versus Fortnightly Cryotherapy For Warts On Extremities - A Pilot Study

    Directory of Open Access Journals (Sweden)

    Eapen Annamma

    1997-01-01

    Full Text Available Forty two patients with verruca vulgaris on the extremities who attended the Government Wenlock Hospital and KMC, Attavar, were subjected to weekly and fortnightly cryotherapy. At the end of 8 weeks, it was found that of the 37 patients who were followed up, 94% in weekly group and 84% in fortnightly group responded to treatment.

  10. Increased neonatal morbidity despite pulmonary maturity for deliveries occurring before 39 weeks.

    Science.gov (United States)

    Fang, Yu Ming Victor; Guirguis, Peter; Borgida, Adam; Feldman, Deborah; Ingardia, Charles; Herson, Victor

    2013-01-01

    To compare neonatal outcomes following deliveries 39 weeks after confirmation of fetal lung maturity with scheduled deliveries ≥39 weeks. A retrospective cohort study examining neonatal outcomes of women who were delivered following documented fetal pulmonary maturity at 36, 37, and 38 weeks compared to women undergoing a scheduled delivery at 39, 40, and 41 weeks. The χ(2)-test and Student's t-test were used to compare categorical and continuous data, respectively. Delivery prior to 39 weeks following fetal pulmonary maturity was associated with a 8.4% composite neonatal morbidity rate as compared to 3.3% for deliveries at 39 weeks or greater (relative risk [RR] 2.9; confidence interval [CI] 2.4-3.6). Neonatal respiratory morbidity was significantly higher (5.4%) for those delivering at less than 39 weeks with documented fetal pulmonary maturity as compared to 2.1% for those delivering at 39 weeks or greater (RR 3.0; CI 2.3-3.9). Increased neonatal morbidity persisted for those delivered prior to 39 weeks even after excluding all diabetics (p 39 weeks regardless of the mode of delivery. Despite fetal pulmonary maturity, delivery before 39 weeks is associated with significantly increased neonatal morbidity when compared to scheduled deliveries at 39 weeks or greater.

  11. 75 FR 20778 - Security Zone; Portland Rose Festival Fleet Week, Willamette River, Portland, OR

    Science.gov (United States)

    2010-04-21

    ...-AA87 Security Zone; Portland Rose Festival Fleet Week, Willamette River, Portland, OR AGENCY: Coast... during the Portland Rose Festival Fleet Week from June 2, 2010, through June 7, 2010. The security zone... is a need to provide a security zone for the 2010 Portland Rose Festival Fleet Week, and there is...

  12. Quantitative feed restriction of Pekin breeder ducks from 3 weeks of ...

    African Journals Online (AJOL)

    0,01) lower in body mass than those restricted from 8 weeks of age. The aversion of mass loss during this period could have contributed to the improved performance recorded during the laying period. At 60 weeks of age, the ducks restricted in intake from. 3 weeks were still highly significantly (P ",;;0,01) lighter in body mass ...

  13. Further decrease in glycated hemoglobin following ingestion of a LoBAG30 diet for 10 weeks compared to 5 weeks in people with untreated type 2 diabetes.

    Science.gov (United States)

    Gannon, Mary C; Hoover, Heidi; Nuttall, Frank Q

    2010-07-29

    We previously determined that a weight-maintenance, non-ketogenic diet containing 30% carbohydrate (CHO), 30% protein, 40% fat, (30:30:40) (LoBAG30) decreased glycated hemoglobin (%tGHb) from 10.8 to 9.1% over a 5 week period in subjects with untreated type 2 diabetes. Both the fasting glucose and postprandial glucose area were decreased. Our objective in the present 10-week study was to determine: 1) whether the above results could be maintained, or even improved (suggesting a metabolic adaptation) and 2) whether the subjects would accept the diet for this longer time period. In addition, protein balance, and a number of other blood and urine constituents were quantified at 5 and at 10 weeks on the LoBAG30 diet to address metabolic adaptation. Eight men with untreated type 2 diabetes were studied over a 10-week period. Blood was drawn and urine was collected over a 24 hour period at the beginning of the study with subjects ingesting a standard diet of 55% CHO, 15% protein, 30% fat, and at the end of 5 and 10 weeks following ingestion of a LoBAG30 diet. Body weight was stable. Fasting glucose decreased by 19% at week 5 and 28% at week 10; 24-h total glucose area decreased by 27% at week 5 and 35% at week 10 compared to baseline. Insulin did not change. Mean %tGHb decreased by 13% at week 5, 25% at week 10, and was still decreasing linearly, indicating that a metabolic adaptation occurred. Serum NEFA, AAN, uric acid, urea, albumin, prealbumin, TSH, Total T3, free T4, B12, folate, homocysteine, creatinine, growth hormone and renin did not differ between weeks 5 and 10. IGF-1 increased modestly. Urinary glucose decreased; urinary pH and calcium were similar. A LoBAG30 diet resulted in continued improvement in glycemic control. This improvement occurred without significant weight loss, with unchanged insulin and glucagon profiles, and without deterioration in serum lipids, blood pressure or kidney function. Extending the duration of time on a LoBAG30 diet from 5 to 10

  14. Further decrease in glycated hemoglobin following ingestion of a LoBAG30 diet for 10 weeks compared to 5 weeks in people with untreated type 2 diabetes

    Directory of Open Access Journals (Sweden)

    Hoover Heidi

    2010-07-01

    Full Text Available Abstract Background We previously determined that a weight-maintenance, non-ketogenic diet containing 30% carbohydrate (CHO, 30% protein, 40% fat, (30:30:40 (LoBAG30 decreased glycated hemoglobin (%tGHb from 10.8 to 9.1% over a 5 week period in subjects with untreated type 2 diabetes. Both the fasting glucose and postprandial glucose area were decreased. Our objective in the present 10-week study was to determine: 1 whether the above results could be maintained, or even improved (suggesting a metabolic adaptation and 2 whether the subjects would accept the diet for this longer time period. In addition, protein balance, and a number of other blood and urine constituents were quantified at 5 and at 10 weeks on the LoBAG30 diet to address metabolic adaptation. Methods Eight men with untreated type 2 diabetes were studied over a 10-week period. Blood was drawn and urine was collected over a 24 hour period at the beginning of the study with subjects ingesting a standard diet of 55% CHO, 15% protein, 30% fat, and at the end of 5 and 10 weeks following ingestion of a LoBAG30 diet. Results Body weight was stable. Fasting glucose decreased by 19% at week 5 and 28% at week 10; 24-h total glucose area decreased by 27% at week 5 and 35% at week 10 compared to baseline. Insulin did not change. Mean %tGHb decreased by 13% at week 5, 25% at week 10, and was still decreasing linearly, indicating that a metabolic adaptation occurred. Serum NEFA, AAN, uric acid, urea, albumin, prealbumin, TSH, Total T3, free T4, B12, folate, homocysteine, creatinine, growth hormone and renin did not differ between weeks 5 and 10. IGF-1 increased modestly. Urinary glucose decreased; urinary pH and calcium were similar. Conclusions A LoBAG30 diet resulted in continued improvement in glycemic control. This improvement occurred without significant weight loss, with unchanged insulin and glucagon profiles, and without deterioration in serum lipids, blood pressure or kidney function

  15. Radiation Metabolomics: Current Status and Future Directions

    Directory of Open Access Journals (Sweden)

    Smrithi eSugumaran Menon

    2016-02-01

    Full Text Available Human exposure to ionizing radiation disrupts normal metabolic processes in cells and organs by inducing complex biological responses that interfere with gene and protein expression. Conventional dosimetry, monitoring of prodromal symptoms and peripheral lymphocyte counts are of limited value as organ and tissue specific biomarkers for personnel exposed to radiation, particularly, weeks or months after exposure. Analysis of metabolites generated in known stress-responsive pathways by molecular profiling helps to predict the physiological status of an individual in response to environmental or genetic perturbations. Thus, a multi-metabolite profile obtained from a high resolution mass spectrometry-based metabolomics platform offers potential for identification of robust biomarkers to predict radiation toxicity of organs and tissues resulting from exposures to therapeutic or non-therapeutic ionizing radiation. Here, we review the status of radiation metabolomics and explore applications as a standalone technology, as well as its integration in systems biology, to facilitate a better understanding of the molecular basis of radiation response. Finally, we draw attention to the identification of specific pathways that can be targeted for the development of therapeutics to alleviate or mitigate harmful effects of radiation exposure.

  16. Lanreotide autogel every 6 weeks compared with Lanreotide microparticles every 3 weeks in patients with well differentiated neuroendocrine tumors: a Phase III Study.

    Science.gov (United States)

    Bajetta, Emilio; Procopio, Giuseppe; Catena, Laura; Martinetti, Antonia; De Dosso, Sara; Ricci, Sergio; Lecchi, Alberto S; Boscani, Paolo F; Iacobelli, Stefano; Carteni, Giacomo; De Braud, Filippo; Loli, Paola; Tartaglia, Andreas; Bajetta, Roberto; Ferrari, Leonardo

    2006-11-15

    The noninferiority of a 6-week dosing schedule of lanreotide Autogel (Lan ATG) at a dose of 120 mg compared with a 3-week dosing schedule of lanreotide microparticles (Lan MP) at a dose of 60 mg was investigated in patients with neuroendocrine tumors (NET). Patients who had sporadic, well differentiated NET with a low grade of malignancy were recruited for this open-label, Phase III, multicenter trial. Patients were randomized to receive either 3 deep subcutaneous injections of Lan ATG (120 mg, every 6 weeks) or 6 intramuscular injections of Lan MP (60 mg, every 3 weeks). Tumor markers, tumor size, and symptoms were assessed between baseline and Week 18. Success was classified as a response that ranged from disappearance to an increase <25% in tumor marker, tumor size, or symptom frequency. Sixty patients were randomized, and 46 patients completed the study. Both for tumor markers and for tumor size, Lan ATG was not inferior to Lan MP (55% and 59% of patients responded on tumor markers, respectively; 68% and 66% of patients responded on tumor size, respectively). There were too few symptomatic patients to compare carcinoid symptoms. Both treatments were tolerated well, and no safety concerns were identified. Lan ATG at a dose of 120 mg every 6 weeks was as effective for controlling NET as Lan MP at a dose of 60 mg every 3 weeks.

  17. The 5x1 DAFNE study protocol: a cluster randomised trial comparing a standard 5 day DAFNE course delivered over 1 week against DAFNE training delivered over 1 day a week for 5 consecutive weeks

    Directory of Open Access Journals (Sweden)

    Elliott Jackie

    2012-11-01

    Full Text Available Abstract Background Structured education programmes are now established as an essential component to assist effective self-management of diabetes. In the case of Type 1 diabetes, the Dose Adjustment For Normal Eating (DAFNE programme improves both glycaemic control and quality of life. Traditionally delivered over five consecutive days, this format has been cited as a barrier to participation by some patients, such as those who work full-time. Some centres in the UK have organised structured education programmes to be delivered one day a week over several consecutive weeks. This type of format may add benefit by allowing more time in which to practice skills between sessions, but may suffer as a result of weaker peer support being generated compared to that formed over five consecutive days. Methods/design We aim to compare DAFNE delivered over five consecutive days (1 week course with DAFNE delivered one day a week over five weeks (5 week course in a randomised controlled trial. A total of 213 patients were randomised to attend either a 1 week or a 5 week course delivered in seven participating centres. Study outcomes (measured at baseline, 6 and 12 months post-course include HbA1c, weight, self-reported rates of severe hypoglycaemia, psychosocial measures of quality of life, and cost-effectiveness. Generalisability was optimised by recruiting patients from DAFNE waiting lists at each centre, and by mailing eligible patients from hospital clinic lists. The inclusion and exclusion criteria were identical to those used to recruit to a standard DAFNE course (e.g., HbA1c Discussion This trial has been designed to test the hypothesis that the benefits of delivering a structured education programme over 5 weeks are comparable to those observed after a 1 week course. The results of the trial and the qualitative sub-study will both inform the design and delivery of future DAFNE courses, and the development of structured education programmes in other

  18. Febrile infection-related status epilepticus in a child after a common infection

    DEFF Research Database (Denmark)

    Andersen, Anne Helene; Hansen, Lars Kjærsgaard

    2014-01-01

    A 13-year-old boy developed seizures and intractable status epilepticus a week after having had a sore throat. Ketogenic diet possibly had some effect. Antibodies to calmodulin dependent protein kinase II were found and could possibly suggest an immunologic aetiology.......A 13-year-old boy developed seizures and intractable status epilepticus a week after having had a sore throat. Ketogenic diet possibly had some effect. Antibodies to calmodulin dependent protein kinase II were found and could possibly suggest an immunologic aetiology....

  19. A prospective randomized cohort study evaluating 3 weeks vs 6 weeks of oral antibiotic treatment in the setting of "maximal medical therapy" for chronic rhinosinusitis.

    Science.gov (United States)

    Sreenath, Satyan B; Taylor, Robert J; Miller, Justin D; Ambrose, Emily C; Rawal, Rounak B; Ebert, Charles S; Senior, Brent A; Zanation, Adam M

    2015-09-01

    Surprisingly, little literature exists evaluating the optimal duration of antibiotic treatment in "maximal medical therapy" for chronic rhinosinusitis (CRS). As such, we investigated whether 3 weeks vs 6 weeks of antibiotic therapy resulted in significant differences in clinical response. A prospective, randomized cohort study was performed with patients assigned to 3-week or 6-week cohorts. Our primary outcome was failure of "maximal medical therapy" and surgical recommendation. Secondary outcomes included changes in pretherapy and posttherapy scores for the Rhinosinusitis Disability Index (RSDI), Chronic Sinusitis Survey (CSS), and computed tomography (CT)-based Lund-Mackay (LM) evaluation. Analyses were substratified based on presence of nasal polyps. Forty patients were randomized to the 3-week or 6-week treatment cohorts, with near-complete clinical follow-up achieved. No significant difference was found between the proportion of patients who failed medical therapy and were deemed surgical candidates between the 2 cohorts (71% vs 68%, p = 1.000). No significant difference was found in the change of RSDI or CSS scores in the 3 vs 6 weeks of treatment groups (mean ± standard error of the mean [SEM]; RSDI: 9.62 ± 4.14 vs 1.53 ± 4.01, p = 0.868; CSS: 5.75 ± 4.36 vs 9.65 ± 5.34, p = 0.573). Last, no significant difference was found in the change of LM scores (3.35 ± 1.11 vs 1.53 ± 0.81, p = 0.829). Based on this data, there is little difference in clinical outcomes between 3 weeks vs 6 weeks of antibiotic treatment as part of "maximal medical therapy" for CRS. Increased duration of antibiotic treatment theoretically may increase risk from side effects and creates higher healthcare costs. © 2015 ARS-AAOA, LLC.

  20. Predictors of placebo group decline in the Alzheimer's disease Assessment Scale-cognitive subscale (ADAS-Cog) in 24 week clinical trials of Alzheimer's disease.

    Science.gov (United States)

    Irizarry, Michael C; Webb, David J; Bains, Chanchal; Barrett, Steven J; Lai, Robert Y; Laroche, Janette P; Hosford, David; Maher-Edwards, Gareth; Weil, John G

    2008-07-01

    One limitation of several recent 24 week Alzheimer's disease (AD) clinical trials was the lack of cognitive decline detected by the AD Assessment Scale-cognitive subscale (ADAS-cog) in the placebo groups, possibly obscuring true medication effects. Data from 733 individuals in the placebo arms of six AD clinical trials performed 1996-1997 were pooled to examine the relationship of clinical, demographic, and genetic characteristics with the 24 week change in ADAS-cog. Baseline cognitive and functional status and the screening-to-baseline change in ADAS-cog were the strongest independent predictors of the 24 week change in ADAS-cog. The ADAS-cog did not detect progression in patients with mild dementia (screening Mini-Mental State Exam, MMSE, >or=20). The change in ADAS-cog from screening to baseline was inversely correlated with the 24 week change score; it was more difficult to detect cognitive decline at 24 weeks if individuals markedly worsened from screening to baseline. The effects of baseline MMSE and screening-to-baseline change in ADAS-cog generalized to the placebo group (N=106) of another AD study performed in 2004-2005. Overcoming lack of placebo decline in AD clinical trials will require scales more sensitive to cognitive decline in mild AD and strategies to reduce within-person variability in outcome measures.

  1. The Effect of an Eight Week Combined Exercise Training on Oxidative Stress and Lipid Peroxidation in Postmenopausal Women with Type 2 Diabetes

    Directory of Open Access Journals (Sweden)

    A Azamian Jazi

    2016-11-01

    years old, BMI 26.47±3.08 kg/m2 from Yazd city were purposefully selected and randomly divided into experimental (n=13 and control (n=14 groups. The experimental group participated in an eight week combined exercise training (three session per week, but during this period, the control group did not participate  in any exercise training program. Superoxide dismutase (SOD, catalase (CAT, malondialdehyde (MDA, fasting blood sugar (FBS and body fat percent were measured before and after the eight-week combined exercise training. Data were analyzed using paired and independent t-test. Statistical significance was set at P < 0.05. Results: Serum SOD and CAT levels significantly increased (p = 0.000 and p = 0.001 respectively and the MDA levels decreased (P = 0.036 in the experimental group after 8 weeks of combined exercise training. Also, FBS (P=0.000 and body fat percent (P=0.005 decreased in the experimental group compared with the control group. Conclusions: It seems that oxidative stress and lipid peroxidation status in postmenopausal women with type 2 diabetes in the experimental group improve after eight weeks of combined exercise training, compared with the control group.

  2. Tango archiving service status

    International Nuclear Information System (INIS)

    Abeille, G.; Pierre-Joseph, S.; Guyot, J.; Ounsy, M.; Rubio, S.; Strangolino, G.; Passuello, R.

    2012-01-01

    In modern scientific instruments like ALBA, ELLETRA or Synchrotron Soleil, the monitoring and tuning of thousands of parameters is essential to drive high-performing accelerators and beamlines. To keep track of these parameters and to easily manage large volumes of technical data, an archiving service is a key component of a modern control system like Tango. To achieve this, a high-available archiving service is provided as a feature of the Tango control system. This archiving service stores data coming from the Tango control system into MySQL or Oracle databases. Tree sub-services are provided: 1) An historical service with an archiving period up to 10 seconds; 2) A short term service providing a few weeks retention with a period up to 100 milliseconds; and 3) A snapshot service which takes 'snapshots' of Tango parameters and can reapply them to the control system on user demand. This paper presents how to obtain a high-performance and scalable service based on our feedback after several years of operation. The deployment architecture in the different Tango institutes will then be detailed. The paper concludes with a description of the next steps and incoming features which will be available in the next future. (authors)

  3. LHC status report

    CERN Multimedia

    CERN Bulletin

    2010-01-01

    Following the great success of the first 3.5 TeV collisions in all four LHC experiments on 30 March, the focus of the LHC commissioning teams has turned to consolidating the beam injection and acceleration procedures.   During the last two weeks, the operators have adopted a cycle of beam commissioning studies by day and the preparation and delivery of collisions during the night shifts. The injection and acceleration processes for the beams are by now well established and almost all feedback systems, which are an essential ingredient for establishing reliable and safe machine operation, have been commissioned. Thanks to special current settings for the quadrupoles that are situated near the collision points, the LHC luminosity at high energy has been increased by a factor of 5 in three of the four experiments. Similar improvements are under way for the fourth experiment. The next steps include adjustments of the LHC machine protection and collimation devices, which will ensure 'stable beam' co...

  4. Elective Cesarean section at 37 weeks is associated with the higher risk of neonatal complications.

    Science.gov (United States)

    Nakashima, Jun-ichi; Yamanouchi, Sohsaku; Sekiya, Shin-ichiro; Hirabayashi, Masato; Mine, Kenji; Ohashi, Atsushi; Tsuji, Shoji; Kasamatsu, Atsushi; Kanzaki, Hideharu; Hirano, Daishi; Kaneko, Kazunari

    2014-08-01

    Elective Cesarean section performed before 39 weeks of gestation may be associated with increased risk of neonatal complications. We retrospectively investigated differences in the neonatal complication rate between 684 newborns delivered by elective Cesarean section at 37 weeks of gestation (n = 390) and those delivered by the same procedure at 38 weeks (n = 294) between 2006 and 2012 at our hospital in order to ascertain whether adverse outcomes differ between the groups. Newborns delivered at 37 weeks had a significantly higher incidence of neonatal intensive care unit admission (p = 0.03), adverse respiratory complications (p complications such as hyperbirilubinemia, hypoglycemia or bacterial infections. In conclusion, the incidence of neonatal complications was higher in newborns delivered at 37 weeks of gestation than in those delivered at 38 weeks via elective Cesarean section. Thus, the procedure should be scheduled at 38 weeks to improve neonatal outcomes.

  5. Biosimilar drugs: Current status.

    Science.gov (United States)

    Kumar, Rajiv; Singh, Jagjit

    2014-07-01

    Biologic products are being developed over the past three decades. The expiry of patent protection for many biological medicines has led to the development of biosimilars in UK or follow on biologics in USA. This article reviews the literature on biosimilar drugs that covers the therapeutic status and regulatory guidelines. Appraisal of published articles from peer reviewed journals for English language publications, search from PubMed, and guidelines from European Medicines Agency, US Food Drug Administration (FDA) and India were used to identify data for review. Literature suggest that biosimilars are similar biological products, i.e., comparable but not identical to the reference product, are not generic version of innovator product and do not ensure therapeutic equivalence. Biosimilars present more challenges than conventional generics and marketing approval is also more complicated. To improve access, US Congress passed the Biologics Price Competition and Innovation act 2009 and US FDA allowed "abbreviated pathway" for their approval. U.S law has defined new standards and terms and EMA scientific guidelines have also set detailed approval standards. India being one of the most preferred manufacturing destinations of biosimilars, there is a need for stringent safety and regulatory guidelines. The New India Guidelines "Draft Guidelines on Similar Biologics were announced in June 2012, by Department of Biotechnology at Boston bio and available online.

  6. LIL laser performance status

    International Nuclear Information System (INIS)

    Julien, X.; Adolf, A.; Bar, E.; Beau, V.; Bordenave, E.; Chies, Th.; Courchinoux, R.; Feral, Ch.; Gendeau, P.; Graillot, H.; Grosset-Grange, C.; Henry, O.; Higonenq, V.; Journot, E.; Lacampagne, L.; Lafond, E.; Le Deroff, L.; Martinez, A.; Patissou, L.; Roques, A.; Thauvin, L.; Di-Nicola, J.M.; Thiell, G.

    2011-01-01

    The Laser Integration Line (LIL) was first designed as a prototype to validate the concepts and the laser architecture of the Laser MegaJoule (LMJ). The LIL facility is a 4-beam laser representing a quad structure of the LMJ. A set of test campaigns were conducted to safely ramp up laser performance. The main goal was to measure quad-specific features such as beam synchronization and focal spot (size, smoothing contrast ratio or irradiation nonuniformity) versus the LMJ requirements. Following the laser commissioning, the LIL has become a major instrument dedicated to the achievement of plasma physics experiments for the French Simulation Program and was also opened to the academic scientific community. One of the attributes of the LIL facility is to be very flexible to accommodate the requests of plasma physicists during campaigns. The LIL is constantly evolving to best meet the needs of target physicists. Changes made or planned are either to improve the quality of laser beams, or to increase the LIL Energy-Power operating space. To optimize preparation and design of shot campaigns, the LIL performance status has been elaborated. It gives information about the characteristics of the laser in terms of near field and far field, defines the steps to maintain performance, explains how the facility responds to the request, details settings (smoothing, shaping of the focal spot, energy, temporal pulse shaping, beam pointing) and gives the limits in energy and power. In this paper, an overview of the LIL performance is presented. (authors)

  7. Nanometals - Status and perspective

    International Nuclear Information System (INIS)

    Faester, S.; Hansen, N.; Huang, X.; Juul Jensen, D.; Ralph, B.

    2012-01-01

    Nanometals and nanotechnology have over the years been covered in papers, books and conferences - also in many Risoe International Symposia, where the 30th in 2009 dealt solely with nanostructured metals. Since then, rapid progress has been made in synthesis, characterization and modeling, and it is timely to discuss status and perspective also with a view on applications in an international forum such as the Risoe Symposium. Both keynote and contributed papers address important current problems illustrating global research and development in this field. Examples are the development of new synthesis techniques followed by characterization and modeling of microstructures both in 2D and 3D now starting to bridge the micrometer scales. The vital area of mechanical behavior is addressed by the development of new testing techniques and a broad effort to characterize and model mechanical properties of metals strengthened by dislocations and twins. This research has now led to new understanding of both strengthening mechanisms and strengh structure relationships based on experiments in combination with analytical and numerical modeling. The holistic approach to research on nanometals demonstrated by these proceedings can guide both scientists and technologists in their future work also with the aim of introducing into society this new group of advanced materials. Such an effort is important, as science and technology today is significantly affected by politics of governments and international institutions, and therefore a new initiative in the pressent is to include a discussion of research and development in the area of nanometals i USA, China and Japan. (Author)

  8. Biocatalysis: A Status Report.

    Science.gov (United States)

    Bommarius, Andreas S

    2015-01-01

    This review describes the status of the fields of biocatalysts and enzymes, as well as existing drawbacks, and recent advances in the areas deemed to represent drawbacks. Although biocatalysts are often highly active and extremely selective, there are still drawbacks associated with biocatalysis as a generally applicable technique: the lack of designability of biocatalysts; their limits of stability; and the insufficient number of well-characterized, ready-to-use biocatalysts. There has been significant progress on the following fronts: (a) novel protein engineering tools, both experimental and computational, have significantly enhanced the toolbox for biocatalyst development. (b) The deactivation of biocatalysts under various stresses can be described quantitatively via rational models. There are several cases of spectacular leaps of stabilization after accumulating all stabilizing mutations found in earlier rounds. The concept that stabilization against one type of stress commonly also stabilizes against other types of stress is now experimentally considerably better founded than a few years ago. (c) A host of developments of novel biocatalysts in the past few years, in part fueled by improved designability and improved methods of stabilization, has considerably broadened the toolbox for synthetic chemistry.

  9. Status of fusion technology

    International Nuclear Information System (INIS)

    Mohan, Ashok

    1978-01-01

    The current status of fusion technology is surveyed. Limited reserves of fossil fuel and dangers of proliferation from nuclear reactors have brought into focus the need to develop an optional energy source. Fusion is being looked upon as an optional energy source which is free from environmental hazards unlike fossil fuels and nuclear reactors. Investments in R and D of fusion energy have increased rapidly in USA, Japan, USSR and European countries. Out of the various fusion fuels known, a mixture of D and T is widely chosen. The main problem in fusion technology is the confinement of plasma for a time sufficient to start the fusion reaction. This can be done magnetically or inertially. The three approaches to magnetic confinement are : (1) tokamak, (2) mirror and (3) pinch. Inertial confinement makes use of lasers or electron beams or ion beams. Both the methods of confinement i.e. magnetic and inertial have problems which are identified and their nature is discussed. (M.G.B.)

  10. Maternal stress and distress and child nutritional status.

    Science.gov (United States)

    Rondó, P H C; Rezende, G; Lemos, J O; Pereira, J A

    2013-04-01

    To assess the relationship between maternal stress and distress in pregnancy and 5-8 years postpartum and child nutritional status. Longitudinal cohort study carried out in Jundiai city, Southeast Brazil, involving 409 women followed throughout pregnancy to 5-8 years postpartum, and respective children. Measures of stress and distress were obtained three times in pregnancy (at gestational ages lower than 16 weeks, from 20 to 26 weeks and from 30 to 36 weeks) and 5-8 years postpartum by the Perceived Stress Scale (PSS), General Health Questionnaire (GHQ) and the State-Trait Anxiety Inventories (STAI). The nutritional status of the children was assessed by the World Health Organization body mass index (BMI) z-score for age. The relationship between child BMI z-score for age and scores of the PSS, GHQ and STAI was evaluated by multivariate linear regression, controlling for confounding variables. BMI z-score for age of the children was negatively associated with maternal scores of the PSS 5-8 years postpartum and scores of the GHQ in the second trimester of pregnancy. BMI of the children was positively associated with maternal BMI and birthweight (R(2)=0.13). There was -0.04 (confidence interval -0.07 to -0.9 × 10(-2)) decrease in child BMI per score unit of the PSS increase, and -0.09 (confidence interval -0.18 to -0.6 × 10(-3)) decrease in child BMI per score unit of the GHQ increase. This study detected a relationship between maternal mental and nutritional status and child nutritional status, implying that if the mother is not physically or mentally well, her capacity for caring for her child may be impaired.

  11. Health status of hostel dwellers

    African Journals Online (AJOL)

    1991-06-15

    Jun 15, 1991 ... Here a high infant mortality rate is examined against ... social situation. A screen for health status in a single survey provides an overview of health status. It provides an unusual opportunity for an additional level of analysis that goes beyond ..... diastolic blood pressure and a higher death rate from hyper-.

  12. Neuropathy and efficacy of once weekly subcutaneous bortezomib in multiple myeloma and light chain (AL amyloidosis.

    Directory of Open Access Journals (Sweden)

    Surbhi Sidana

    Full Text Available Randomized studies have shown that bortezomib (BTZ can be given weekly via intravenous (IV route or twice weekly via subcutaneous (SC route with lower neuropathy risk and no loss of anti-myeloma efficacy compared to original standard IV twice weekly schedule. Weekly SC should therefore yield the best therapeutic index and is widely used but has not been compared to established administration schedules in the context of a clinical trial.Comprehensive electronic medical record review was done for disease control and neuropathy symptoms of 344 consecutive patients who received their first BTZ-containing regimen for myeloma or AL amyloidosis before or after we changed to SC weekly in December 2010. Univariate and multivariable analyses were carried out that adjusted for age, underlying disease, concurrently used anticancer agents, underlying conditions predisposing to neuropathy, and number of prior regimens compared SC weekly to other schedules.Fifty-three patients received BTZ SC weekly, 17 SC twice weekly, 127 IV weekly and 147 IV twice weekly. Risk for neuropathy of any grade was higher with other schedules compared to SC weekly (44.3% vs. 26.9%, p = 0.001 while response rate was similar (72.1% vs. 76.6%, respectively, p = 0.15. Multivariable analyses upheld higher neuropathy risk (Odds ratio 2.45, 95% CI 1.26-4.76, p = 0.008 while the likelihood of not achieving a response (= partial response or better was comparable (Odds ratio 1.25, 95% CI 0.58-2.71, p = 0.56 for other schedules compared to SC weekly, respectively. Lower neuropathy risk translated into longer treatment duration when BTZ was started SC weekly (p = 0.001.Weekly SC BTZ has activity comparable to other schedules and causes low rates of neuropathy.

  13. Amniotic Fluid Arginine from Gestational Weeks 13 to 15 Is a Predictor of Birth Weight, Length, and Head Circumference

    Directory of Open Access Journals (Sweden)

    Astrid Bjørke-Jenssen

    2017-12-01

    Full Text Available Arginine is a constituent of proteins and a precursor for polyamines and nitric oxide, and is essential for placentation, angiogenesis, and growth. Maternal plasma arginine concentrations are found to be lower in pregnancies complicated by fetal growth restriction, and arginine supplementation in later pregnancy is reported to increase birth weight. We measured arginine and the metabolites asymmetric dimethylarginine (ADMA and symmetric dimethylarginine (SDMA in the amniotic fluid obtained in pregnancy weeks 13 to 15 from 363 pregnancies with a documented normal outcome and related the concentrations to birth weight, length, and head circumference. Arginine was higher in the amniotic fluid from female (mean 40.8 (SD 10.6 µmol/L compared to male fetuses (37.4 (SD 11.2 µmol/L, p = 0.003. Despite the gender difference, arginine in the amniotic fluid from gestational weeks 13–15 was the strongest predictor for birth weight, length, and head circumference. ADMA was a strong predictor for birth weight and length, SDMA for birth weight, while Arg/ADMA and Arg/SDMA only predicted head circumference in multiple linear regression models. Due to increased arginine demands, pregnancy is considered a state of relative arginine deficiency. Our findings reflect the importance of a good maternal arginine status in early pregnancy, an observation that should be evaluated in an intervention study.

  14. Tolerance of weekly metronomic paclitaxel and carboplatin as neoadjuvant chemotherapy in advanced ovarian cancer patients who are unlikely to tolerate 3 weekly paclitaxel and carboplatin

    Directory of Open Access Journals (Sweden)

    S B Dessai

    2016-01-01

    Full Text Available Objective: There are little data regarding safety and effectiveness of neoadjuvant chemotherapy (NACT in patients who are considered unfit for receiving 3 weekly paclitaxel and carboplatin. The aim of this study was to examine the toxicity and response rates of weekly paclitaxel and carboplatin as NACT in such cohort of patients. Methods: Study population included advanced ovarian cancer patients who were unlikely to tolerate 3 weekly paclitaxel and carboplatin and hence received weekly paclitaxel (80 mg/m 2 and carboplatin AUC-2 as NACT. The data regarding the baseline characteristics, chemotherapy tolerance, completion rates, toxicity (Common Terminology Criteria for Adverse Events version 4.02, and radiological response rates are presented. SPSS version 16 was used for analysis. Descriptive statistics is presented. Results: Eleven patients received this schedule. Nine patients completed nine cycles of NACT. Except one, all patients completed NACT with an average relative dose intensity of >0.8. There was no chemotherapy-related mortality. Grade 3-4 life-threatening complications were seen in two patients. The post NACT response rate was 100%. Conclusions: Weekly paclitaxel and carboplatin chemotherapy is safe and efficacious in patients who are unsuitable for 3 weekly paclitaxel and carboplatin chemotherapy schedules.

  15. Between Status and Contract?

    Directory of Open Access Journals (Sweden)

    Thorsten Keiser

    2013-01-01

    Full Text Available This contribution deals with unfree labour in Germany from the early modern age until the beginning of the 20th century. It presents the main conclusions of a book published in 2013 on this subject in German. Unfree labour is not identified in the first place with slavery or any other labour relationship based on status. Instead, this study aims at an analysis of freedom and coercion in contractual labour relationships. It will be argued that in Germany contractual labour relationships before 1800 were embedded in a legal system that strongly restricted contractual autonomy and aimed at the suppression of free labour markets. The scope of this legislation was to guarantee efficient labour performance, which was not only perceived as being in the personal interest of an employer, but as a fundamental element of the common good. After 1800 the system changed to more incentive-based legislation that established freedom of contract for labour relations. Nevertheless, coercion in order to perform the contractual duties of a work contract remained important for many groups of workers, especially farmhands and industrial workers. The last criminal sanctions for breaches of labour contracts were only abolished in the revolution of 1919. This development shows the difficulties German law had in extending the principles of private law to workers. When a system of free labour was fully established, the issue of unemployment and economic problems, especially in the Weimar Republic, required a new system of protective rules. The history of free market based labour contracts in Germany was therefore very short, with state intervention shi ing from control and coercion to social assistance.

  16. Status of thorium technology

    International Nuclear Information System (INIS)

    Garg, R.K.; Raghavan, R.V.; Karve, V.M.; Narayandas, G.R.

    1977-01-01

    Although a number of studies have been conducted in various countries to evolve reactor systems based on thorium fuel cycle, its use, so far, is limited to only a few reactors. However, for countries having large reserves of thorium, its utilization is of great significance for their nuclear power programmes. Reasonably assured world resources of thorium in the lower price range have been estimated at more than 500,000 tons of ThO 2 . While most of these resources are in placer deposits in various parts of the world, some vein deposits and uranium ores are other important sources of thorium. Monazite, the most important mineral of thorium, is found in the beach sand deposits along with other heavy minerals like ilmenite, rutile, zircon, and sillimanite etc. Mining of these deposits is usually carried out by suction dredging and separation of monazite from other minerals is effected by a combination of magnetic, electrostatic and gravity separation techniques. Chemical processing of monazite is carried out either by sulphuric acid or caustic treatment, followed by separation of the rare earths and thorium by partial precipitation or leaching. The thorium concentrate is further processed to obtain mantle grade thorium nitrate by chemical purification steps whereas solvent extraction using TBP is adopted for making nuclear-grade material. The purified thorium nitrate is converted to the oxide usually by precipitation as oxalate followed by calcination. The oxide is reduced directly with calcium or converted to the chloride or fluoride and then reduced by calcium or magnesium to obtain thorium metal. Various fuel designs based on the metal or its alloys, mixed oxides or carbides, and dispersed type fuel elements have been developed and accordingly, different fabrication techniques have been employed. Work on irradiation of thorium containing fuel elements and separation of U 233 is being carried out. This paper reviews the status of thorium technology in the world with

  17. Status of ITER

    International Nuclear Information System (INIS)

    Aymar, R.

    2002-01-01

    At the end of engineering design activities (EDA) in July 2001, all the essential elements became available to make a decision on construction of ITER. A sufficiently detailed and integrated engineering design now exists for a generic site, has been assessed for feasibility, and costed, and essential physics and technology R and D has been carried out to underpin the design choices. Formal negotiations have now begun between the current participants--Canada, Euratom, Japan, and the Russian Federation--on a Joint Implementation Agreement for ITER which also establishes the legal entity to run ITER. These negotiations are supported on technical aspects by Coordinated Technical Activities (CTA), which maintain the integrity of the project, for the good of all participants, and concentrate on preparing for procurement by industry of the longest lead items, and for formal application for a construction license with the host country. This paper highlights the main features of the ITER design. With cryogenically-cooled magnets close to neutron-generating plasma, the design of shielding with adequate access via port plugs for auxiliaries such as heating and diagnostics, and of remote replacement and refurbishing systems for in-vessel components, are particularly interesting nuclear technology challenges. Making a safety case for ITER to satisfy potential regulators and to demonstrate, as far as possible at this stage, the environmental attractiveness of fusion as an energy source, is also important. The paper gives illustrative details on this work, and an update on the progress of technical preparations for construction, as well as the status of the above negotiations

  18. Tumor volume regression during preoperative chemoradiotherapy for rectal cancer: a prospective observational study with weekly MRI.

    Science.gov (United States)

    Van den Begin, Robbe; Kleijnen, Jean-Paul; Engels, Benedikt; Philippens, Marielle; van Asselen, Bram; Raaymakers, Bas; Reerink, Onne; De Ridder, Mark; Intven, Martijn

    2017-11-20

    Few data is available on rectal tumor shrinkage during preoperative chemoradiotherapy (CRT). This regression pattern is interesting to optimize timing of dose escalation on the tumor. Gross tumor volumes (GTV) were contoured by two observers on magnetic resonance imaging (MRI) obtained before, weekly during, 2-4 weeks after, and 7-8 weeks after a 5-week course of concomitant CRT for rectal cancer. Overall, 120 MRIs were acquired in 15 patients. A statistically significant tumor volume reduction is seen from the first week, and between any two time points (p < .007). At the end of CRT, 46.3% of the initial tumor volume remained, and 32.4% at time of surgery. PTV measured 61.2% at the end of treatment. Tumor shrinkage is the fastest in the beginning of treatment (26%/week), slows down to 7%/week in the last 2 weeks of CRT, and finally to 1.3%/week in the last 5 weeks before surgery. The main rectal tumor regression occurs during CRT course itself, and mostly in the first half, with shrinking speed decreasing over the course. This suggests that a sequential boost is preferably done after the elective fields, yielding an average PTV-reduction of 39%. A simultaneous integrated boost strategy could benefit from adaptive planning during the course.

  19. Conservative management of preterm premature rupture of membranes beyond 32 weeks' gestation: is it worthwhile?

    Science.gov (United States)

    Tsafrir, Z; Margolis, G; Cohen, Y; Cohen, A; Laskov, I; Levin, I; Mandel, D; Many, A

    2015-01-01

    We aimed to investigate whether conservative management of preterm premature rupture of membranes (PPROM) at 32-34 weeks' gestation improves outcome. In this retrospective analysis of singleton pregnancies, the study group included patients with PPROM at 28-34 weeks' gestation and the control group included patients presented with spontaneous preterm delivery at 28-34 weeks' gestation. Both groups were subdivided according to gestational age - early (28-31 weeks' gestation) versus late (32-34 weeks' gestation). Adverse neonatal outcome included neonatal death, intraventricular haemorrhage grade 3/4, respiratory distress syndrome, periventricular leucomalacia and neonatal sepsis. The study and control groups included 94 and 86 women, respectively. The study group had a lower incidence of adverse neonatal outcome at the earlier weeks (28-31), compared with the control group at the same gestational age. In contrast, at 32-34 weeks' gestation no difference in the risk for adverse neonatal outcome was noticed. Additionally, within the study group, chorioamnionitis rate was significantly higher among those who delivered at 32-34 weeks' gestation (p < 0.01). No advantage for conservative management of PPROM was demonstrated beyond 31 weeks' gestation. Moreover, conservative management of PPROM at 32-34 weeks' gestation may expose both mother and neonate to infectious morbidity.

  20. Effects of a 12-week strength training program on experimented fencers' movement time.

    Science.gov (United States)

    Redondo, Juan C; Alonso, Cruz J; Sedano, Silvia; de Benito, Ana M

    2014-12-01

    The purpose of this study was to determine the effects of a 12-week strength training program on movement time (MT) on fencers of national level. Twelve male fencers were randomly divided into 2 groups: the control group (CG: N = 6; age, 22.3 ± 8.1 years) and the treatment group (TG: N = 6; age, 24.8 ± 7.2 years). The CG fencers followed the standard physical conditioning program, which was partially modified for the TG. The TG participated in a 12-week strength training program divided into 2 parts: maximal strength training, including weightlifting exercises (2 days a week for 6 weeks) and explosive strength training, with combined weights and plyometric exercises (2 days a week for 6 weeks). Body mass, body fat, muscle mass, jumping ability, maximal strength, reaction time, and MT were measured on 4 separate occasions. The TG demonstrated significant increases (p ≤ 0.05) in maximal strength and jumping ability after 6 weeks of training and in MT after 12 weeks. These improvements remained unaltered during the 4-week detraining period. It may be concluded that a 12-week strength training program can improve maximal and explosive strength, and these increases can be transferred to MT performance. However, fencers need time to transfer the gains.

  1. The incremental treatment of ESRD: a low-protein diet combined with weekly hemodialysis may be beneficial for selected patients.

    Science.gov (United States)

    Caria, Stefania; Cupisti, Adamasco; Sau, Giovanna; Bolasco, Piergiorgio

    2014-10-29

    Infrequent dialysis, namely once-a-week session combined with very low-protein, low-phosphorus diet supplemented with ketoacids was reported as a useful treatment schedule for ESRD patients with markedly reduced residual renal function but preserved urine output. This study reports our findings from the application of a weekly dialysis schedule plus less severe protein restriction (standard low-protein low-phosphorus diet) in stage 5 CKD patients with consistent dietary discipline. This is a multicenter, prospective controlled study, including 68 incident CKD patients followed in a pre-dialysis clinic with Glomerular Filtration Rate 5 to 10 ml/min/1.73/ m2 who became unstable on the only medical treatment. They were offered to begin a Combined Diet Dialysis Program (CDDP) or a standard thrice-a-week hemodialysis (THD): 38 patients joined the CDDP, whereas 30 patients chose THD. Patients were studied at baseline, 6 and 12 months; hospitalization and survival rate were followed-up for 24 months. Volume output and residual renal function were maintained in the CDDP Group while those features dropped quickly in THD Group. Throughout the study, CDDP patients had a lower erythropoietin resistance index, lower β2 microglobulin levels and lower need for cinacalcet of phosphate binders than THD, and stable parameters of nutritional status. At 24 month follow-up, 39.4% of patients were still on CDDP; survival rates were 94.7% and 86.8% for CDDP and THD patients, respectively, but hospitalization rate was much higher in THD than in CDDP patients. The cost per patient per year resulted significantly lower in CDDP than in THD Group. This study shows that a CDDP served to protect the residual renal function, to maintain urine volume output and to preserve a good nutritional status. CDDP also blunted the rapid β2 microglobulin increase and resulted in better control of anemia and calcium-phosphate abnormalities. CDDP was also associated with a lower hospitalization rate and

  2. Effects of an 18-week strength training program on low-handicap golfers' performance.

    Science.gov (United States)

    Alvarez, María; Sedano, Silvia; Cuadrado, Gonzalo; Redondo, Juan Carlos

    2012-04-01

    The purpose of this study was to determine the effects of an 18-week strength training program on variables related to low-handicap golfers' performance. Ten right-handed male golfers, reporting a handicap of 5 or less, were randomly divided into two groups: the control group (CG) (N = 5, age: 23.9 ± 6.7 years) and the treatment group (TG) (N = 5, age: 24.2 ± 5.4 years). CG players followed the standard physical conditioning program for golf, which was partially modified for the TG. The TG participated in an 18-week strength training program divided into three parts: maximal strength training including weightlifting exercises (2 days a week for 6 weeks), explosive strength training with combined weights and plyometric exercises (2 days a week for 6 weeks), and golf-specific strength training, including swings with a weighted club and accelerated swings with an acceleration tubing system (3 days a week for 6 weeks). Body mass, body fat, muscle mass, jumping ability, isometric grip strength, maximal strength (RM), ball speed, and golf club mean acceleration were measured on five separate occasions. The TG demonstrated significant increases (p strength after 6 weeks of training and in driving performance after 12 weeks. These improvements remained unaltered during the 6-week golf-specific training period and even during a 5-week detraining period. It may be concluded that an 18-week strength training program can improve maximal and explosive strength and these increases can be transferred to driving performance; however, golfers need time to transfer the gains.

  3. PENINGKATAN STATUS GIZI ANAK BALITA DI LINGKUNGAN KELUARGA PEKERJA WANITA

    Directory of Open Access Journals (Sweden)

    M. Saidin

    2012-11-01

    Full Text Available A study of nutritional improvement in children under five years old of working women families was conducted in the subdistrict of Kali Wungu, district of Kudus, Central Java. A total of 83 preschool children (19-55 months old with mild under nutrition was divided into two groups. The first was intervention group received food supplement containing 300 kcal of energy and 5 g of protein, three times a week for the duration of 14 weeks. The second was control group, did not receive any food supplement. Baseline data collection included identity, body weight and height, haemoglobine, haematocrit, serum ferritin, food consumption of the children and socioeconomic status of the household and was conducted in both groups before starting with the supplementary feeding. Just after baseline data collection, both groups received deworming (combantrin syrup. Multivitamins were given every day for tire first ten days and another ten days in the middle of the intervention. While iron pill (Ferro sulphate 30 mg was given weekly. The evaluation were conducted after 1-1 weeks of intervention. The results of the study revealed that: 1 the energy intake of daily food consumption of both groups of children was lower than Recomended Dietary Allowances (61% RDA,· 2 the average energy intake originating from the portion of the food supplement consumed was only 225 Kcal (75% of the total energy provided; 3 supplementary feeding three times per week for 14 weeks together with providing a medicine package consisting of deworming (combantrin, multivitamins (provit and iron pill increases nutritional status based on weight for age by 2.7%; 4 supplementary feeding three times per week for 14 weeks together with medicine package raises Hb levels 0.61 g/dl; 5 the medicine package only, without supplementary feeding increases Hb levels 0.21 g/dl (control group; 6 supplementary feeding activities for children of working women families could be managed by caders as volunteers

  4. Information week...

    CERN Multimedia

    Staff Association

    2007-01-01

    Here we are at the end of a series of public information meetings held in the Departments. We thank all those who came to find out about the subjects presented and to exchange ideas and opinions. All the positive feedback we have received shows how much you appreciate these meetings. And well, so do we!

  5. Four weeks of IV iron supplementation reduces perceived fatigue and mood disturbance in distance runners.

    Directory of Open Access Journals (Sweden)

    Amy Woods

    Full Text Available To determine the effect of intravenous iron supplementation on performance, fatigue and overall mood in runners without clinical iron deficiency.Fourteen distance runners with serum ferritin 30-100 µg · L(-1 were randomly assigned to receive three blinded injections of intravenous ferric-carboxymaltose (2 ml, 100 mg, IRON or normal saline (PLACEBO over four weeks (weeks 0, 2, 4. Athletes performed a 3,000 m time trial and 10 × 400 m monitored training session on consecutive days at week 0 and again following each injection. Hemoglobin mass (Hbmass was assessed via carbon monoxide rebreathing at weeks 0 and 6. Fatigue and mood were determined bi-weekly until week 6 via Total Fatigue Score (TFS and Total Mood Disturbance (TMD using the Brief Fatigue Inventory and Brunel Mood Scale. Data were analyzed using magnitude-based inferences, based on the unequal variances t-statistic and Cohen's Effect sizes (ES.Serum ferritin increased in IRON only (Week 0: 62.8 ± 21.9, Week 4: 128.1 ± 46.6 µg · L(-1; p = 0.002 and remained elevated two weeks after the final injection (127.0 ± 66.3 µg · L(-1, p = 0.01, without significant changes in Hbmass. Supplementation had a moderate effect on TMD of IRON (ES -0.77 with scores at week 6 lower than PLACEBO (ES -1.58, p = 0.02. Similarly, at week 6, TFS was significantly improved in IRON vs. PLACEBO (ES -1.54, p = 0.05. There were no significant improvements in 3,000 m time in either group (Week 0 vs. Week 4; Iron: 625.6 ± 55.5 s vs. 625.4 ± 52.7 s; PLACEBO: 624.8 ± 47.2 s vs. 639.1 ± 59.7 s; but IRON reduced their average time for the 10 × 400 m training session at week 2 (Week 0: 78.0 ± 6.6 s, Week 2: 77.2 ± 6.3; ES-0.20, p = 0.004.During 6 weeks of training, intravenous iron supplementation improved perceived fatigue and mood of trained athletes with no clinical iron deficiency, without concurrent improvements in oxygen transport capacity or performance.

  6. Reducing status quo bias in choice experiments

    DEFF Research Database (Denmark)

    Bonnichsen, Ole; Ladenburg, Jacob

    2015-01-01

    to be superior, i.e. a status quo effect. However, in the stated preference literature, the tendency to choose the alternative representing the status quo situation seems to exceed real life status quo effects. Accordingly, status quo bias can be a problem. In the Choice Experiment literature, status quo bias...

  7. Weekly taxane-anthracycline combination regimen versus tri-weekly anthracycline-based regimen for the treatment of locally advanced breast cancer: a randomized controlled trial.

    Science.gov (United States)

    Tan, Qiu-Wen; Luo, Ting; Zheng, Hong; Tian, Ting-Lun; He, Ping; Chen, Jie; Zeng, He-Lin; Lv, Qing

    2017-03-07

    Extensive studies have confirmed the efficacy of taxanes in combination with anthracycline-based chemotherapy on breast cancer. However, few studies have assessed the efficacy of weekly taxane-anthracycline regimens on locally advanced breast cancer. This study was to compare the efficacy and safety of a weekly taxane-anthracycline regimen with those of tri-weekly anthracycline-based regimen in patients with locally advanced breast cancer. Patients with locally advanced breast cancer were randomized to receive 4-6 cycles of neoadjuvant chemotherapy with tri-weekly 5-fluorouracil-epirubicin-cyclophosphamide (FEC) regimen or weekly paclitaxel-epirubicin (PE) regimen. The primary endpoint was the pathologic complete response (pCR) rate. Other endpoints included the clinical tumor response, breast-conserving surgery rate, and adverse events. Between March 2010 and September 2013, 293 patients were randomized to the FEC (n = 151) and PE (n = 142) arms. The overall clinical response rate was significantly higher in the PE arm than in the FEC arm (76.06% vs. 59.95%, P = 0.001). Consistently, the post-chemotherapy pathologic T and N stages were significantly lower in the PE arm than in the FEC arm (P breast-conserving surgery. Most adverse events were comparable in both arms, with more severe neutropenia in the PE arm than in the FEC arm (11.97% vs. 5.96%, P = 0.031). In patients with locally advanced breast cancer, weekly PE was not superior to FEC in terms of pCR. However, weekly PE has a higher response rate and superior down-staging effects. On this account, the PE regimen may be considered an alternative option for locally advanced breast cancer. Long-term follow-up data are needed to confirm the efficacy of this regimen on locally advanced breast cancer. Trial registration Chinese clinical trial registry, ChiCTR-TRC-10001043, September 21, 2014.

  8. Sentinel-2 Mission status

    Science.gov (United States)

    Hoersch, Bianca; Colin, Olivier; Gascon, Ferran; Arino, Olivier; Spoto, Francois; Marchese, Franco; Krassenburg, Mike; Koetz, Benjamin

    2016-04-01

    Copernicus is a joint initiative of the European Commission (EC) and the European Space Agency (ESA), designed to establish a European capacity for the provision and use of operational monitoring information for environment and security applications. Within the Copernicus programme, ESA is responsible for the development of the Space Component, a fully operational space-based capability to supply earth-observation data to sustain environmental information Services in Europe. The Sentinel missions are Copernicus dedicated Earth Observation missions composing the essential elements of the Space Component. In the global Copernicus framework, they are complemented by other satellites made available by third-parties or by ESA and coordinated in the synergistic system through the Copernicus Data-Access system versus the Copernicus Services. The Copernicus Sentinel-2 mission provides continuity to services relying on multi-spectral high-resolution optical observations over global terrestrial surfaces. Sentinel-2 capitalizes on the technology and the vast experience acquired in Europe and the US to sustain the operational supply of data for services such as forest monitoring, land cover changes detection or natural disasters management. The Sentinel-2 mission offers an unprecedented combination of the following capabilities: ○ Systematic global coverage of land surfaces: from 56°South to 84°North, coastal waters and Mediterranean sea; ○ High revisit: every 5 days at equator under the same viewing conditions with 2 satellites; ○ High spatial resolution: 10m, 20m and 60m; ○ Multi-spectral information with 13 bands in the visible, near infra-red and short wave infra-red part of the spectrum; ○ Wide field of view: 290 km. The data from the Sentinel-2 mission are available openly and freely for all users with online easy access since December 2015. The presentation will give a status report on the Sentinel-2 mission, and outlook for the remaining ramp-up Phase, the

  9. Large block test status report

    International Nuclear Information System (INIS)

    Wilder, D.G.; Lin, W.; Blair, S.C.

    1997-01-01

    This report is intended to serve as a status report, which essentially transmits the data that have been collected to date on the Large Block Test (LBT). The analyses of data will be performed during FY98, and then a complete report will be prepared. This status report includes introductory material that is not needed merely to transmit data but is available at this time and therefore included. As such, this status report will serve as the template for the future report, and the information is thus preserved

  10. Antenatal corticosteroids and perinatal outcomes in infants born at 23-25 weeks of gestation.

    Science.gov (United States)

    Goya, M; Cespedes, M C; Camba, F; Capote, S; Felipe, A; Reixachs, A; Medina, D; Gorraiz, V; Pin, S; Halachian, C; Gracia, A; Perapoch, J; Cabero, L; Carreras, E

    2015-01-01

    To evaluate the perinatal results of infants born between 23 and 25.6 weeks of gestation. Medical charts of all women giving birth prematurely (23-25.6 w) from January 2005 to December 2011 were retrospectively reviewed. Cases of malformed infants or deliveries elsewhere were excluded. 198 infants were included. Chorioamnionitis occurred in 86 (43.4%) of the whole group: 26 (86.7%) in the 23-week; 35 (53.8%) in the 24-week and 25 (24.3%) in the 25-week groups. Foetal maturation with antenatal corticosteroids was complete in 119 cases (60.1%): 4 (13.3%) in the 23-week; 35 (53.8%) in the 24-week and 80 (77.7%) in the 25-week groups. Foetal death at birth occurred in 22 cases (11%) and 61 newborns (30.8%) died in the neonatal period. Of the 106 survivors with 2 years complete follow-up, 45 infants (42.4%) did not present sequelae; 16 infants (15.1%) had severe sequelae. A 66.6% (4) of infants born at 23 weeks of gestation did not present sequelae compared with a 32.3% (11) at 24 weeks and 45.4% (30) at 25 weeks. The chorioamnionitis rate was higher when gestational age was lower. The foetal maturation rate was higher when gestational age was higher. A low severe sequelae rate was observed in the whole series, particularly in the 23-week group where the rate was lower than expected; however, these results could have been influenced by the small size of the 23-week group.

  11. Effect of a 16-Week Yoga Program on Blood Pressure in Healthy College Students

    Science.gov (United States)

    Nelson, Debra; Reed, Justy; Buck, Sarah M.

    2014-01-01

    The purpose of this study was to examine the effect of a 16-week yoga program on blood pressure (BP) in healthy college students. Twenty-five students (Mage = 28.24, SD = 10.64) participated in yoga class twice per week for 16 weeks. Thirty-one students (Mage = 28.77, SD = 7.23) attended a lecture (control condition) at approximately the same time…

  12. Continued pregnancy and vaginal delivery after 32 weeks of gestation for monoamniotic twins.

    Science.gov (United States)

    Anselem, O; Mephon, A; Le Ray, C; Marcellin, L; Cabrol, D; Goffinet, F

    2015-11-01

    To report the outcomes of 38 monoamniotic twin pregnancies managed homogeneously to assess whether continuing the pregnancy past 32 weeks of gestation and vaginal delivery are reasonable options. Single-centre retrospective study including all monoamniotic pregnancies managed over a 20-year period at Port-Royal Obstetrics Department, Paris, France. In the study department, both continuation of the pregnancy up to 36 weeks of gestation and vaginal delivery are allowed for monoamniotic pregnancies in some conditions. Perinatal outcomes are described and then compared according to mode of delivery for patients who gave birth at or after 32 weeks of gestation. Three of the 38 pregnancies included fetal malformations; in two of these cases, both fetuses died in utero at 26 weeks of gestation. In cases without malformations, one twin died in utero in two women at 28.0 and 29.2 weeks of gestation, and both fetuses died in two other women at 24.0 and 24.5 weeks of gestation. Mean gestational age at delivery was 32.9 weeks (range 24.0-36.3). Five women gave birth between 22 and 26 weeks of gestation, six women gave birth between 27 and 31 weeks of gestation, and 27 women gave birth at or after 32 weeks of gestation (26 after excluding those with fetal malformations). No intrauterine or neonatal deaths were observed at or after 32 weeks of gestation. The 28 infants delivered vaginally did not differ significantly from the 22 infants born by caesarean section in terms of umbilical artery pH or 5-min Apgar scores. Continuation of monoamniotic pregnancies beyond 32 weeks of gestation and trial of vaginal delivery are both reasonable options if the parents agree, and optimal surveillance is provided. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  13. Temperature during the last week of incubation. III. Effects on chicken embryo physiology.

    Science.gov (United States)

    Maatjens, C M; van Roovert-Reijrink, I A M; Engel, B; van der Pol, C W; Kemp, B; van den Brand, H

    2017-05-01

    We investigated effects of eggshell temperature (EST) of 35.6, 36.7, 37.8, or 38.9°C applied from d of incubation (E) 15, E17, or E19 onward on chicken embryo physiology. A total of 2,850 first-grade eggs of a 43-week-old Ross 308 broiler breeder flock were incubated at an EST of 37.8°C until E15. From E15, E17, or E19 onward, eggs were incubated at an EST of 35.6, 36.7, 37.8, or 38.9°C. Plasma glucose, uric acid, and lactate concentrations, and hepatic glycogen amount and concentration were measured at E15, E17, E19, internal pipping (IP), external pipping (EP), and hatch.An EST of 38.9°C applied from E15 onward decreased the amount of hepatic glycogen from E19 to IP and resulted in a lower glycogen amount at IP compared to all other EST. At EP, when oxygen (O2) becomes largely available, an EST of 38.9°C resulted in a higher glycogen amount and concentration compared to IP, which suggests that plasma glucose between IP and EP might be used for building up hepatic glycogen reserves. However, hepatic glycogen levels remained considerably lower at IP, EP, and hatch at an EST of 38.9°C, compared to an EST of 35.6 and 36.7°C.Opposite to an EST of 38.9°C, from IP onward, an EST of 35.6°C resulted in a higher glycogen amount and concentration compared to all other EST, which might be caused by the higher O2 availability relative to the lower metabolic rate, which provided time to build up glycogen stores from excessive glucose. A higher availability of hepatic glycogen might contribute to an improved physiological status of the broiler chicken embryo toward hatch. Hepatic gluconeogenesis is crucial for developing embryos, as glucose is the major energy source from IP until hatch. At hatch, no effect of EST was found for glucose, uric acid, or lactate.Results of this study emphasize that EST of 35.6 and 36.7°C from E15 onward appear to be beneficial for chicken embryo physiology. © 2016 Poultry Science Association Inc.

  14. Executive Functioning and Learning Skills of Adolescent Children Born at Fewer than 26 Weeks of Gestation.

    Directory of Open Access Journals (Sweden)

    A Farooqi

    Full Text Available To assess the cognitive and behavioral aspects of executive functioning (EF and learning skills in extremely preterm (EPT children compared with term control children aged 10 to 15 years.A total of 132 of 134 (98% of all eligible survivors EPT children born at the 2 Swedish regional tertiary care centers from 1992 to 1998 (mean age = 12 years, mean birth weight = 718 g, and mean gestational age = 24.4 weeks and 103 matched term controls were assessed. General intelligence was assessed using the Wechsler Intelligence Scale for Children (WISC-III-R, and cognitive aspects of EF were analyzed using EF-sensitive subscales of the WISC-III-R and Tower test of the Delis-Kaplan Executive Function Scale (D-KEFS. Behaviors related to EF and learning skills were assessed using the Five to Fifteen questionnaire, which is a validated parent and teacher instrument. Academic performance in school was assessed by teachers' responses on Achenbach's Teachers Report Form. Analyses performed included multivariate analyses of covariance (ANCOVA and MANCOVA and logistic regression analyses.The EPT children displayed significant deficits in cognitive aspects of EF compared with the controls, exhibiting decreases on the order of 0.9 SD to 1.2 SD for tasks of verbal conceptual reasoning, verbal and non-verbal working memory, processing speed and planning ability (P 70 and without major NSI revealed no interactions, but significant main effects were observed for the behavioral composite executive function score, group status (EPT vs control and FSIQ, for which all effect sizes were medium to large. The corresponding findings of MANCOVA of the parent-reported learning skills were very similar. According to the teachers' ratings, the EPT children were less well adjusted to the school environment.EPT children born in the 1990s who received active perinatal care are at an increased risk of executive dysfunction, even after excluding children with significant

  15. Executive Functioning and Learning Skills of Adolescent Children Born at Fewer than 26 Weeks of Gestation

    Science.gov (United States)

    Farooqi, A.; Adamsson, M.; Serenius, F.; Hägglöf, B.

    2016-01-01

    Aims To assess the cognitive and behavioral aspects of executive functioning (EF) and learning skills in extremely preterm (EPT) children compared with term control children aged 10 to 15 years. Methods A total of 132 of 134 (98% of all eligible survivors) EPT children born at the 2 Swedish regional tertiary care centers from 1992 to 1998 (mean age = 12 years, mean birth weight = 718 g, and mean gestational age = 24.4 weeks) and 103 matched term controls were assessed. General intelligence was assessed using the Wechsler Intelligence Scale for Children (WISC-III-R), and cognitive aspects of EF were analyzed using EF-sensitive subscales of the WISC-III-R and Tower test of the Delis-Kaplan Executive Function Scale (D-KEFS). Behaviors related to EF and learning skills were assessed using the Five to Fifteen questionnaire, which is a validated parent and teacher instrument. Academic performance in school was assessed by teachers’ responses on Achenbach’s Teachers Report Form. Analyses performed included multivariate analyses of covariance (ANCOVA and MANCOVA) and logistic regression analyses. Results The EPT children displayed significant deficits in cognitive aspects of EF compared with the controls, exhibiting decreases on the order of 0.9 SD to 1.2 SD for tasks of verbal conceptual reasoning, verbal and non-verbal working memory, processing speed and planning ability (P children with major neurosensory impairment (NSI) or a Full Scale intelligence quotient (FSIQ) of children reported significantly more EF-related behavioral problems. MANCOVA of teacher-reported learning skills in children with FSIQ >70 and without major NSI revealed no interactions, but significant main effects were observed for the behavioral composite executive function score, group status (EPT vs control) and FSIQ, for which all effect sizes were medium to large. The corresponding findings of MANCOVA of the parent-reported learning skills were very similar. According to the teachers

  16. Executive Functioning and Learning Skills of Adolescent Children Born at Fewer than 26 Weeks of Gestation.

    Science.gov (United States)

    Farooqi, A; Adamsson, M; Serenius, F; Hägglöf, B

    2016-01-01

    To assess the cognitive and behavioral aspects of executive functioning (EF) and learning skills in extremely preterm (EPT) children compared with term control children aged 10 to 15 years. A total of 132 of 134 (98% of all eligible survivors) EPT children born at the 2 Swedish regional tertiary care centers from 1992 to 1998 (mean age = 12 years, mean birth weight = 718 g, and mean gestational age = 24.4 weeks) and 103 matched term controls were assessed. General intelligence was assessed using the Wechsler Intelligence Scale for Children (WISC-III-R), and cognitive aspects of EF were analyzed using EF-sensitive subscales of the WISC-III-R and Tower test of the Delis-Kaplan Executive Function Scale (D-KEFS). Behaviors related to EF and learning skills were assessed using the Five to Fifteen questionnaire, which is a validated parent and teacher instrument. Academic performance in school was assessed by teachers' responses on Achenbach's Teachers Report Form. Analyses performed included multivariate analyses of covariance (ANCOVA and MANCOVA) and logistic regression analyses. The EPT children displayed significant deficits in cognitive aspects of EF compared with the controls, exhibiting decreases on the order of 0.9 SD to 1.2 SD for tasks of verbal conceptual reasoning, verbal and non-verbal working memory, processing speed and planning ability (P learning skills in children with FSIQ >70 and without major NSI revealed no interactions, but significant main effects were observed for the behavioral composite executive function score, group status (EPT vs control) and FSIQ, for which all effect sizes were medium to large. The corresponding findings of MANCOVA of the parent-reported learning skills were very similar. According to the teachers' ratings, the EPT children were less well adjusted to the school environment. EPT children born in the 1990s who received active perinatal care are at an increased risk of executive dysfunction, even after excluding children with

  17. Treatment with α-Lipoic Acid over 16 Weeks in Type 2 Diabetic Patients with Symptomatic Polyneuropathy Who Responded to Initial 4-Week High-Dose Loading

    Science.gov (United States)

    Garcia-Alcala, Hector; Santos Vichido, Celia Isabel; Islas Macedo, Silverio; Genestier-Tamborero, Christelle Nathalie; Minutti-Palacios, Marissa; Hirales Tamez, Omara; García, Carlos; Ziegler, Dan

    2015-01-01

    Effective treatment of diabetic sensorimotor polyneuropathy remains a challenge. To assess the efficacy and safety of α-lipoic acid (ALA) over 20 weeks, we conducted a multicenter randomized withdrawal open-label study, in which 45 patients with type 2 diabetes and symptomatic polyneuropathy were initially treated with ALA (600 mg tid) for 4 weeks (phase 1). Subsequently, responders were randomized to receive ALA (600 mg qd; n = 16) or to ALA withdrawal (n = 17) for 16 weeks (phase 2). During phase 1, the Total Symptom Score (TSS) decreased from 8.9 ± 1.8 points to 3.46 ± 2.0 points. During phase 2, TSS improved from 3.7 ± 1.9 points to 2.5 ± 2.5 points in the ALA treated group (p < 0.05) and remained unchanged in the ALA withdrawal group. The use of analgesic rescue medication was higher in the ALA withdrawal group than ALA treated group (p < 0.05). In conclusion, in type 2 diabetic patients with symptomatic polyneuropathy who responded to initial 4-week high-dose (600 mg tid) administration of ALA, subsequent treatment with ALA (600 mg qd) over 16 weeks improved neuropathic symptoms, whereas ALA withdrawal was associated with a higher use of rescue analgesic drugs. This trial is registered with ClinicalTrials.gov Identifier: NCT02439879. PMID:26345602

  18. Once-weekly teriparatide reduces the risk of vertebral fracture in patients with various fracture risks: subgroup analysis of the Teriparatide Once-Weekly Efficacy Research (TOWER) trial.

    Science.gov (United States)

    Nakano, Tetsuo; Shiraki, Masataka; Sugimoto, Toshitsugu; Kishimoto, Hideaki; Ito, Masako; Fukunaga, Masao; Hagino, Hiroshi; Sone, Teruki; Kuroda, Tatsuhiko; Nakamura, Toshitaka

    2014-07-01

    Once-weekly teriparatide (human parathyroid hormone [1-34]) (56.5 μg for 72 weeks) injections provided a vertebral fracture risk reduction in Japanese osteoporotic patients evaluated in the Teriparatide Once-Weekly Efficacy Research (TOWER) trial. Using data from the TOWER trial, a subgroup analysis was performed to study the efficacy of once-weekly teriparatide for a variety of baseline clinical risk factors in placebo (n = 281) and teriparatide (n = 261) groups. Significant fracture risk reductions were observed in the subgroups of individuals aged teriparatide group, no incident fracture was observed in the subgroups with a prevalent vertebral fracture number of 0, with grade 0-2 vertebral deformity, or with lumbar BMD ≥2.5 SD. Significant risk reduction was observed in all of the bone turnover marker and estimated glomerular filtration rate subgroups. In conclusion, once-weekly 56.5 μg teriparatide injection reduced the vertebral fracture risk in patients with varying degrees of fracture risk, age, vertebral fracture number and grade, bone turnover level, and renal function.

  19. Treatment with α-Lipoic Acid over 16 Weeks in Type 2 Diabetic Patients with Symptomatic Polyneuropathy Who Responded to Initial 4-Week High-Dose Loading

    Directory of Open Access Journals (Sweden)

    Hector Garcia-Alcala

    2015-01-01

    Full Text Available Effective treatment of diabetic sensorimotor polyneuropathy remains a challenge. To assess the efficacy and safety of α-lipoic acid (ALA over 20 weeks, we conducted a multicenter randomized withdrawal open-label study, in which 45 patients with type 2 diabetes and symptomatic polyneuropathy were initially treated with ALA (600 mg tid for 4 weeks (phase 1. Subsequently, responders were randomized to receive ALA (600 mg qd; n=16 or to ALA withdrawal (n=17 for 16 weeks (phase 2. During phase 1, the Total Symptom Score (TSS decreased from 8.9 ± 1.8 points to 3.46 ± 2.0 points. During phase 2, TSS improved from 3.7 ± 1.9 points to 2.5 ± 2.5 points in the ALA treated group (p<0.05 and remained unchanged in the ALA withdrawal group. The use of analgesic rescue medication was higher in the ALA withdrawal group than ALA treated group (p<0.05. In conclusion, in type 2 diabetic patients with symptomatic polyneuropathy who responded to initial 4-week high-dose (600 mg tid administration of ALA, subsequent treatment with ALA (600 mg qd over 16 weeks improved neuropathic symptoms, whereas ALA withdrawal was associated with a higher use of rescue analgesic drugs. This trial is registered with ClinicalTrials.gov Identifier: NCT02439879.

  20. Current status of pulmonary metastasectomy

    DEFF Research Database (Denmark)

    Hornbech, Kåre; Ravn, Jesper; Steinbrüchel, Daniel Andreas

    2011-01-01

    for unresected patients. In this article, we discuss the current status on pulmonary metastasectomy. Preoperative assessment and selection of surgical candidates is covered. The different surgical strategies including surgical approach, unilateral versus bilateral exploration, lymph node dissection, and repeat...