tuted tetrahydropyrrolo[1,2-a] pyrimidone derivatives as key templates (Figure 1). Initially we attempted to synthesize these targets through the condensation of the beta keto esters with the corresponding 2-amino-. 3,4-tetrahydropyrrole derivatives as reported in the literature.5 This is shown in Scheme 1. However, this.
Robert T. Stibrany
Full Text Available The title complex, [CuCl2(C21H22N4O], contains a bis(benzimidazole unit with a chiral bridgehead C atom that forms part of a tetrahydropyrrole ring fused to one of the benzimidazoles. The chelate angle is 90.45 (9° and the dihedral angle between the essentially planar benzimidazole fragments is 26.68 (9°. The CuII coordination geometry lies approximately midway between tetrahedral and square planar. Overall, each chiral molecule contains six fused rings, and a racemic mixture is formed with symmetry-related enantiomers. In the crystal, C—H...π and C—H...Cl interactions link molecules into a supramolecular chain along the a-axis direction.