Search for Violation of CPT and Lorentz Invariance in $B^0_s$ Meson Oscillations using the D0 Detector

Energy Technology Data Exchange (ETDEWEB)

Van Kooten, R. [Indiana U.

2017-01-01

A search is presented for CPT-violating effects in the mixing of $B^0_s$ mesons using the D0 detector at the Fermilab Tevatron Collider. The CPT-violating asymmetry in the decay $B^0_s \\rightarrow \\mu^{\\pm} D_s^{\\mp} X$ as a function of sidereal phase is measured. No evidence for CPT-violating effects is observed and limits are placed on CPT- and Lorentz-invariance violating coupling coefficients.

CPT and Lorentz violation as signatures for Planck-scale physics

International Nuclear Information System (INIS)

Lehnert, Ralf

2009-01-01

In recent years, the breakdown of spacetime symmetries has been identified as a promising research field in the context of Planck-scale phenomenology. For example, various theoretical approaches to the quantum-gravity problem are known to accommodate minute violations of CPT invariance. This talk covers various topics within this research area. In particular, some mechanisms for spacetime-symmetry breaking as well as the Standard-Model Extension (SME) test framework will be reviewed; the connection between CPT and Lorentz invariance in quantum field theory will be exposed; and the a few experimental CPT tests with emphasis on matter-antimatter comparisons will be discussed.

A review of the latest CPLEAR results on $T$ violation and $CPT$ invariance in the neutral-kaon system

CERN Document Server

Zavrtanik, D; Apostolakis, Alcibiades J; Aslanides, Elie; Backenstoss, Gerhard; Bargassa, P; Behnke, O; Benelli, A; Bertin, V; Blanc, F; Bloch, P; Carlson, P J; Carroll, M; Cawley, E; Chertok, M B; Danielsson, M; Dejardin, M; Derré, J; Ealet, A; Eleftheriadis, C; Fetscher, W; Fidecaro, Maria; Filipcic, A; Francis, D; Fry, J; Gabathuler, Erwin; Gamet, R; Gerber, H J; Go, A; Haselden, A; Hayman, P J; Henry-Coüannier, F; Hollander, R W; Jon-And, K; Kettle, P R; Kokkas, P; Kreuger, R; Le Gac, R; Leimgruber, F; Mandic, I; Manthos, N; Marel, Gérard; Mikuz, M; Miller, J; Montanet, François; Müller, A; Nakada, Tatsuya; Pagels, B; Papadopoulos, I M; Pavlopoulos, P; Polivka, G; Rickenbach, R; Roberts, B L; Ruf, T; Schäfer, M; Schaller, L A; Schietinger, T; Schopper, A; Tauscher, Ludwig; Thibault, C; Touchard, F; Touramanis, C; van Eijk, C W E; Vlachos, S; Weber, P; Wigger, O; Wolter, M; Zavrtanik, D; Zimmerman, D

2001-01-01

The CPLEAR experiment has studied the symmetries which may exist between matter and antimatter by comparing the time evolution of K /sup 0/ and K/sup 0/. A number of measurements allowed the determination, with high precision and in a rather complete way, of the parameters of the time evolution and the related symmetry properties. T and CPT could be disentangled from CP and the first direct measurement of T violation was performed. The CPT invariance was directly tested through the parameter Re( delta ), while Im( delta ) was best determined from the Bell-Steinberger relation. The K /sup 0/ and K/sup 0/ mass and decay width differences were then bound to less than a few times 10/sup -18/ GeV. (19 refs).

Extrinsic CPT Violation in Neutrino Oscillations

International Nuclear Information System (INIS)

Ohlsson, Tommy

2004-01-01

In this talk, we investigate extrinsic CPT violation in neutrino oscillations in matter with three flavors. Note that extrinsic CPT violation is different from intrinsic CPT violation. Extrinsic CPT violation is one way of quantifying matter effects, whereas intrinsic CPT violation would mean that the CPT invariance theorem is not valid. We present analytical formulas for the extrinsic CPT probability differences and discuss their implications for long-baseline experiments and neutrino factory setups

Search for Violations of Lorentz Invariance and CPT Symmetry in B-(s)(0) Mixing

NARCIS (Netherlands)

Aaij, R.; Beteta, C. Abellan; Adeva, B.; Adinolfi, M.; Ajaltouni, Z.; Akar, S.; Albrecht, J.; Alessio, F.; Alexander, M.; Ali, S.; Alkhazov, G.; Cartelle, P. Alvarez; Alves, A. A.; Amato, S.; Amerio, S.; Amhis, Y.; An, L.; Anderlini, L.; Andreassi, G.; Andreotti, M.; Andrews, J. E.; Appleby, R. B.; Gutierrez, O. Aquines; Archilli, F.; d'Argent, P.; Artamonov, A.; Artuso, M.; Aslanides, E.; Auriemma, G.; Baalouch, M.; Bachmann, S.; Back, J. J.; Badalov, A.; Baesso, C.; Baker, S.; Baldini, W.; Barlow, R. J.; Barschel, C.; Barsuk, S.; Barter, W.; Batozskaya, V.; Battista, V.; Beaucourt, L.; Beddow, J.; Bedeschi, F.; Bediaga, I.; Bel, L. J.; Onderwater, C. J. G.; Pellegrino, A.; Tolk, S.

2016-01-01

Violations of CPT symmetry and Lorentz invariance are searched for by studying interference effects in B-0 mixing and in B-s(0) mixing. Samples of B-0 -> J/psi K-S(0) and B-0(s) -> J/psi K+K- decays are recorded by the LHCb detector in proton-proton collisions at center-of-mass energies of 7 and 8

A measurement of the $\\tau$ mass and the first CPT test with $\\tau$ leptons

CERN Document Server

Abbiendi, G.; Ainsley, C.; Akesson, P.F.; Alexander, G.; Allison, John; Anderson, K.J.; Arcelli, S.; Asai, S.; Ashby, S.F.; Axen, D.; Azuelos, G.; Bailey, I.; Ball, A.H.; Barberio, E.; Barlow, Roger J.; Batley, J.R.; Baumann, S.; Behnke, T.; Bell, Kenneth Watson; Bella, G.; Bellerive, A.; Bentvelsen, S.; Bethke, S.; Biebel, O.; Bloodworth, I.J.; Bock, P.; Bohme, J.; Boeriu, O.; Bonacorsi, D.; Boutemeur, M.; Braibant, S.; Bright-Thomas, P.; Brigliadori, L.; Brown, Robert M.; Burckhart, H.J.; Cammin, J.; Capiluppi, P.; Carnegie, R.K.; Carter, A.A.; Carter, J.R.; Chang, C.Y.; Charlton, David G.; Ciocca, C.; Clarke, P.E.L.; Clay, E.; Cohen, I.; Cooke, O.C.; Couchman, J.; Couyoumtzelis, C.; Coxe, R.L.; Cuffiani, M.; Dado, S.; Dallavalle, G.Marco; Dallison, S.; Davis, R.; Roeck, A.de; Dervan, P.; Desch, K.; Dienes, B.; Dixit, M.S.; Donkers, M.; Dubbert, J.; Duchovni, E.; Duckeck, G.; Duerdoth, I.P.; Estabrooks, P.G.; Etzion, E.; Fabbri, F.; Fanti, M.; Faust, A.A.; Feld, L.; Ferrari, P.; Fiedler, F.; Fleck, I.; Ford, M.; Frey, A.; Furtjes, A.; Futyan, D.I.; Gagnon, P.; Gary, J.W.; Gaycken, G.; Geich-Gimbel, C.; Giacomelli, G.; Giacomelli, P.; Gingrich, D.M.; Glenzinski, D.; Goldberg, J.; Grandi, C.; Graham, K.; Gross, E.; Grunhaus, J.; Gruwe, M.; Gunther, P.O.; Hajdu, C.; Hanson, G.G.; Hansroul, M.; Hapke, M.; Harder, K.; Harel, A.; Hargrove, C.K.; Harin-Dirac, M.; Hauke, A.; Hauschild, M.; Hawkes, C.M.; Hawkings, R.; Hemingway, R.J.; Hensel, C.; Herten, G.; Heuer, R.D.; Hildreth, M.D.; Hill, J.C.; Hobson, P.R.; Hocker, James Andrew; Hoffman, Kara Dion; Homer, R.J.; Honma, A.K.; Horvath, D.; Hossain, K.R.; Howard, R.; Huntemeyer, P.; Igo-Kemenes, P.; Imrie, D.C.; Ishii, K.; Jacob, F.R.; Jawahery, A.; Jeremie, H.; Jones, C.R.; Jovanovic, P.; Junk, T.R.; Kanaya, N.; Kanzaki, J.; Karapetian, G.; Karlen, D.; Kartvelishvili, V.; Kawagoe, K.; Kawamoto, T.; Kayal, P.I.; Keeler, R.K.; Kellogg, R.G.; Kennedy, B.W.; Kim, D.H.; Klein, K.; Klier, A.; Kobayashi, T.; Kobel, M.; Kokott, T.P.; Komamiya, S.; Kowalewski, Robert V.; Kress, T.; Krieger, P.; von Krogh, J.; Kuhl, T.; Kupper, M.; Kyberd, P.; Lafferty, G.D.; Landsman, H.; Lanske, D.; Lawson, I.; Layter, J.G.; Leins, A.; Lellouch, D.; Letts, J.; Levinson, L.; Liebisch, R.; Lillich, J.; List, B.; Littlewood, C.; Lloyd, A.W.; Lloyd, S.L.; Loebinger, F.K.; Long, G.D.; Losty, M.J.; Lu, J.; Ludwig, J.; Macchiolo, A.; Macpherson, A.; Mader, W.; Mannelli, M.; Marcellini, S.; Marchant, T.E.; Martin, A.J.; Martin, J.P.; Martinez, G.; Mashimo, T.; Mattig, Peter; McDonald, W.John; McKenna, J.; McMahon, T.J.; McPherson, R.A.; Meijers, F.; Mendez-Lorenzo, P.; Merritt, F.S.; Mes, H.; Michelini, A.; Mihara, S.; Mikenberg, G.; Miller, D.J.; Mohr, W.; Montanari, A.; Mori, T.; Nagai, K.; Nakamura, I.; Neal, H.A.; Nisius, R.; O'Neale, S.W.; Oakham, F.G.; Odorici, F.; Ogren, H.O.; Oh, A.; Okpara, A.; Oreglia, M.J.; Orito, S.; Pasztor, G.; Pater, J.R.; Patrick, G.N.; Patt, J.; Pfeifenschneider, P.; Pilcher, J.E.; Pinfold, J.; Plane, David E.; Poli, B.; Polok, J.; Pooth, O.; Przybycien, M.; Quadt, A.; Rembser, C.; Rick, H.; Robins, S.A.; Rodning, N.; Roney, J.M.; Rosati, S.; Roscoe, K.; Rossi, A.M.; Rozen, Y.; Runge, K.; Runolfsson, O.; Rust, D.R.; Sachs, K.; Saeki, T.; Sahr, O.; Sang, W.M.; Sarkisian, E.K.G.; Sbarra, C.; Schaile, A.D.; Schaile, O.; Scharff-Hansen, P.; Schmitt, S.; Schroder, Matthias; Schumacher, M.; Schwick, C.; Scott, W.G.; Seuster, R.; Shears, T.G.; Shen, B.C.; Shepherd-Themistocleous, C.H.; Sherwood, P.; Siroli, G.P.; Skuja, A.; Smith, A.M.; Snow, G.A.; Sobie, R.; Soldner-Rembold, S.; Spagnolo, S.; Sproston, M.; Stahl, A.; Stephens, K.; Stoll, K.; Strom, David M.; Strohmer, R.; Surrow, B.; Talbot, S.D.; Tarem, S.; Taylor, R.J.; Teuscher, R.; Thiergen, M.; Thomas, J.; Thomson, M.A.; Torrence, E.; Towers, S.; Trefzger, T.; Trigger, I.; Trocsanyi, Z.; Tsur, E.; Turner-Watson, M.F.; Ueda, I.; Vannerem, P.; Verzocchi, M.; Voss, H.; Vossebeld, J.; Waller, D.; Ward, C.P.; Ward, D.R.; Watkins, P.M.; Watson, A.T.; Watson, N.K.; Wells, P.S.; Wengler, T.; Wermes, N.; Wetterling, D.; White, J.S.; Wilson, G.W.; Wilson, J.A.; Wyatt, T.R.; Yamashita, S.; Zacek, V.; Zer-Zion, D.

2000-01-01

We measure the mass of the tau lepton to be 1775.1+-1.6(stat)+-1.0(sys t.) MeV using tau pairs from Z0 decays. To test CPT invariance we compare the masses of the positively and negatively charged tau leptons. The relative mass difference is found to be smaller than 3.0 10^-3 at the 90% confidence level.

Kinetics of Interactions of Matter, Antimatter and Radiation Consistent with Antisymmetric (CPT-Invariant Thermodynamics

Directory of Open Access Journals (Sweden)

A.Y. Klimenko

2017-05-01

Full Text Available This work investigates the influence of directional properties of decoherence on kinetics rate equations. The physical reality is understood as a chain of unitary and decoherence events. The former are quantum-deterministic, while the latter introduce uncertainty and increase entropy. For interactions of matter and antimatter, two approaches are considered: symmetric decoherence, which corresponds to conventional symmetric (CP-invariant thermodynamics, and antisymmetric decoherence, which corresponds to antisymmetric (CPT-invariant thermodynamics. Radiation, in its interactions with matter and antimatter, is shown to be decoherence-neutral. The symmetric and antisymmetric assumptions result in different interactions of radiation with matter and antimatter. The theoretical predictions for these differences are testable by comparing absorption (emission of light by thermodynamic systems made of matter and antimatter. Canonical typicality for quantum mixtures is briefly discussed in Appendix A.

Hermiticity and CPT in string theory

International Nuclear Information System (INIS)

Sonoda, Hidenori

1989-01-01

In the application of conformal field theory to string theory S-matrix elements are obtained from correlation functions of vertex operators. By studying the relation between the vertex operators for the incoming states and those for the outgoing states we obtain two results: First we show that hermiticity of the string vertices is equivalent to the CPT invariance of the corresponding conformal field theory. Secondly we prove that the S-matrix elements in any string theory in flat space-time background are invariant under CPT. (orig.)

Discrete symmetries (C,P,T) in noncommutative field theories

International Nuclear Information System (INIS)

Sheikh-Jabbari, M.M.

2000-01-01

In this paper we study the invariance of the noncommutative gauge theories tinder C, P and T transformations. For the noncommutative space (when only the spatial part of θ is non-zero) we show that NCQED is Parity invariant. In addition, we show that under charge conjugation the theory on noncommutative R θ 4 is transformed to the theory on R -θ 4 , so NCQED is a CP violating theory. The theory remains invariant under time reversal if, together with proper changes in fields, we also change θ by -θ. Hence altogether NCQED is CPT invariant. Moreover we show that the CPT invariance holds for general noncommutative space-time. (author)

Lorentz and CPT violation in the Standard-Model Extension

Energy Technology Data Exchange (ETDEWEB)

Lehnert, Ralf, E-mail: ralehner@indiana.edu [Indiana University Center for Spacetime Symmetries (United States)

2013-03-15

Lorentz and CPT invariance are among the symmetries that can be investigated with ultrahigh precision in subatomic physics. Being spacetime symmetries, Lorentz and CPT invariance can be violated by minuscule amounts in many theoretical approaches to underlying physics that involve novel spacetime concepts, such as quantized versions of gravity. Regardless of the underlying mechanism, the low-energy effects of such violations are expected to be governed by effective field theory. This talk provides a survey of this idea and includes an overview of experimental efforts in the field.

Anomalous Lorentz and CPT violation

Science.gov (United States)

Klinkhamer, F. R.

2018-01-01

If there exists Lorentz and CPT violation in nature, then it is crucial to discover and understand the underlying mechanism. In this contribution, we discuss one such mechanism which relies on four-dimensional chiral gauge theories defined over a spacetime manifold with topology ℛ3 × S 1 and periodic spin structure for the compact dimension. It can be shown that the effective gauge-field action contains a local Chern-Simons-like term which violates Lorentz and CPT invariance. For arbitrary Abelian U(1) gauge fields with trivial holonomies in the compact direction, this anomalous Lorentz and CPT violation has recently been established perturbatively with a Pauli-Villars-type regularization and nonperturbatively with a lattice regularization based on Ginsparg-Wilson fermions.

Extrinsic CPT violation in neutrino oscillations in matter

International Nuclear Information System (INIS)

Jacobson, Magnus; Ohlsson, Tommy

2004-01-01

We investigate matter-induced (or extrinsic) CPT violation effects in neutrino oscillations in matter. Especially, we present approximate analytical formulas for the CPT-violating probability differences for three flavor neutrino oscillations in matter with an arbitrary matter density profile. Note that we assume that the CPT invariance theorem holds, which means that the CPT violation effects arise entirely because of the presence of matter. As special cases of matter density profiles, we consider constant and step-function matter density profiles, which are relevant for neutrino oscillation physics in accelerator and reactor long baseline experiments as well as neutrino factories. Finally, the implications of extrinsic CPT violation on neutrino oscillations in matter for several past, present, and future long baseline experiments are estimated

$CPT$ violation searches and prospects for LHCb

CERN Document Server

van Tilburg, Jeroen

2015-03-06

An overview of current experimental bounds on $CPT$ violation in neutral meson mixing is given. New values for the $CPT$ asymmetry in the $B^0$ and $B_s^0$ systems are deduced from BaBar, Belle and LHCb data. With dedicated analyses, LHCb will be able to further improve the bounds on $CPT$ violation in the $D^0$, $B^0$ and $B_s^0$ systems. Since $CPT$ violation implies violation of Lorentz invariance, the observed $CPT$ asymmetry will exhibit sidereal- and boost-dependent variations. Such $CPT$-violating and Lorentz-violating effects are accommodated in the framework of the Standard-Model Extension (SME). The large boost of the neutral mesons produced at LHCb results in a high sensitivity to the corresponding SME coefficients. For the $B^0$ and $B_s^0$ systems, using existing LHCb data, we determine with high precision the SME coefficients that are not varying with sidereal time. With a full sidereal analysis, LHCb will be able to improve the existing SME bounds in the $D^0$, $B^0$ and $B_s^0$ systems by up t...

Recent results on CP and CPT tests at KLOE/KLOE-2

Energy Technology Data Exchange (ETDEWEB)

Di Domenico, A., E-mail: antonio.didomenico@roma1.infn.it [Department of Physics, Sapienza University of Rome, and INFN Sezione di Roma, Rome (Italy); Silarski, M., E-mail: Michal.Silarski@lnf.infn.it [Institute of Physics, Jagiellonian University, Cracow (Poland)

2012-12-15

Neutral kaon pairs produced in ϕ decays offer a unique possibility to perform fundamental tests of discrete symmetries. Among the most recent results obtained by the KLOE experiment at DAΦNE, the Frascati ϕ-factory, there is the new best limit on the branching ratio of the CP-violating decay K{sub S}→3π{sup 0}, BR<2.6×10{sup −8} at 90% C.L.. The search for possible violations of the CPT symmetry and Lorentz invariance in the context of the Standard-Model Extension (SME) is also described; the new analysis approach fully exploits quantum interferometry in ϕ→K{sub S}K{sub L}→π{sup +}π{sup −}, π{sup +}π{sup −} decays. Finally the status and perspectives of the new data taking campaign with the KLOE-2 experiment at the upgraded DAΦNE machine are briefly reviewed.

Experimental searches for CP and CPT symmetries violation in the neutral kaons system

International Nuclear Information System (INIS)

Debu, P.

1996-01-01

The aim of this lecture is to give an overview of the experiments devoted to the study and research of CP, T and CPT symmetries invariance violations in the system of neutral K mesons. The discovery of K mesons has provided crucial informations for the elaboration of the standard model. However, the observation of CP violation has remained confined to the K system. The origin of the observed CP violation remains hypothetic. Its origin could be a complex phase in the mixing matrix of quarks. In the standard model of electroweak interactions, several evidences of the CP violation exist: the observed K neutral mesons (K L and K S ) are not proper states of CP and are due to CP violation in the K 0 - anti-K 0 mixture. On the other hand, the model predicts also a CP violation in decay amplitudes, named direct CP violation. Important experiments have been carried out for its demonstration. The K system is also the most precise test for CPT invariance. A description of the experiments in progress developed to improve the precision of these tests is given. The plan of the lecture is the following: after a recall of K 0 - anti-K 0 phenomenology, some important steps in the CP violation study are described. Then, the regeneration phenomenon is briefly described and two of the most recent measurements of the direct CP violation parameter are analysed. Finally, the CPT invariance tests are described with their parameters and the measurements in progress. A review of the principal results is given in conclusion with their improvements expected in a near future. (J.S.). 71 refs., 4 figs., 4 tabs

Test results of CPT-deployed vertical electrode arrays at the DOE Hanford Site

International Nuclear Information System (INIS)

Narbutovskih, S.M.; Daily, W.; Ramirez, A.L.; Morey, R.M.

1997-01-01

Field studies were conducted at the DOE Hanford Site to test cone penetrometer installation of vertical electrode arrays (VEA) for use with Electrical Resistivity Tomography (ERT). Most VEA installation methods in current use are not economic for environmental applications. The cone penetrometer technology (CPT) can provide an economic and relatively non-intrusive installation method. However, a VEA with deployable and properly functioning electrodes was required. Results of the design, installation and testing of CPT VEAs are reported in this paper. Several designs were developed and bench tested for use with the CPT. After initial field installation studies, one design was chosen for further testing at the DOE Hanford Site. Four VEAs were each pushed to 100 feet in 4 days. To test the CPT VEAs, an infiltration experiment was conducted with cross VEA tomographic data collected for three vertical planes. These data were processed using the electrical resistivity tomography code developed by Lawrence Livermore National Laboratory (LLNL). Tomographic images for each vertical plane tracked the subsurface resistivity changes associated with the migrating fluid. It is concluded from these test results that the CPT is a viable method for installing VEAs. The VEAs were rapidly and economically installed to the maximum depth required, data of adequate quality were obtained and tomographic images from the infiltration experiment verified that the CPT VEAs provide viable ERT data

Results on CP, T, CPT symmetries with tagged $K^{0} and K^{0}$ by CPLEAR

CERN Document Server

Angelopoulos, Angelos; Aslanides, Elie; Backenstoss, Gerhard; Bargassa, P; Behnke, O; Benelli, A; Bertin, V; Blanc, F; Bloch, P; Carlson, P J; Carroll, M; Cawley, E; Chertok, M B; Dapielsson, M; Dejardin, M; Derré, J; Ealet, A; Eleftheriadis, C; Faravel, L; Fetscher, W; Fidecaro, Maria; Filipcic, A; Francis, D; Fry, J; Gabathuler, Erwin; Gamet, R; Gerber, H J; Go, A; Haselden, A; Hayman, P J; Henry-Coüannier, F; Hollander, R W; Jon-And, K; Kettle, P R; Kokkas, P; Kreuger, R; Le Gac, R; Leimgruber, F; Mandic, I; Manthos, N; Marel, Gérard; Mikuz, M; Miller, J; Montanet, François; Müller, A; Nakada, Tatsuya; Pagels, B; Papadopoulos, I M; Pavlopoulos, P; Polivka, G; Rickenbach, R; Roberts, B L; Ruf, T; Scafer, M; Schaller, L A; Schietinger, T; Schopper, A; Tauscher, Ludwig; Thibault, C; Touchard, F; Touramanis, C; van Eijk, C W E; Vlachos, S; Weber, P; Wigger, O; Wolter, M; Zavrtanik, D; Zimmerman, D

1999-01-01

We report the results of the CPLEAR experiment on CP-, T- and CPT- symmetries in the neutral kaon system. CPLEAR has experimentally determined, for the first time, the violation of T invariance by a direct method using semileptonic decays. The CPT symmetry is tested through the parameters re( delta ) with a precision of a few 10/sup -4/ and Im( delta ), from the Bell-Steinberger relation, with a precision of 10/sup -5/. This allows the mass equality between the K /sup 0/ and K/sup 0/ to be tested down to the level of 10/sup -19/ Ge V. (11 refs).

Using time-dependent indirect CP asymmetries to measure T and CPT violation in B0-Bbar0 mixing

Science.gov (United States)

Karan, Anirban; Nayak, Abinash Kumar; Sinha, Rahul; London, David

2018-06-01

Quantum field theory, which is the basis for all of particle physics, requires that all processes respect CPT invariance. It is therefore of paramount importance to test the validity of CPT conservation. In this Letter, we show that the time-dependent, indirect CP asymmetries involving B decays to a CP eigenstate contain enough information to measure T and CPT violation in B0-Bbar0 mixing, in addition to the standard CP-violating weak phases. Entangled B0Bbar0 states are not required (so that this analysis can be carried out at LHCb, as well as at the B factories), penguin pollution need not be neglected, and the measurements can be made using Bd0 or Bs0 mesons.

Prospects for testing Lorentz and CPT symmetry with antiprotons

Science.gov (United States)

Vargas, Arnaldo J.

2018-03-01

A brief overview of the prospects of testing Lorentz and CPT symmetry with antimatter experiments is presented. The models discussed are applicable to atomic spectroscopy experiments, Penning-trap experiments and gravitational tests. Comments about the sensitivity of the most recent antimatter experiments to the models reviewed here are included. This article is part of the Theo Murphy meeting issue `Antiproton physics in the ELENA era'.

Dimensional reduction of a Lorentz and CPT-violating Maxwell-Chern-Simons model

International Nuclear Information System (INIS)

Belich, H. Jr.; Helayel Neto, J.A.; Ferreira, M.M. Jr.; Maranhao Univ., Sao Luiz, MA; Orlando, M.T.D.; Espirito Santo Univ., Vitoria, ES

2003-01-01

Taking as starting point a Lorentz and CPT non-invariant Chern-Simons-like model defined in 1+3 dimensions, we proceed realizing its dimensional to D = 1+2. One then obtains a new planar model, composed by the Maxwell-Chern-Simons (MCS) sector, a Klein-Gordon massless scalar field, and a coupling term that mixes the gauge field to the external vector, ν μ . In spite of breaking Lorentz invariance in the particle frame, this model may preserve the CPT symmetry for a single particular choice of ν μ . Analyzing the dispersion relations, one verifies that the reduced model exhibits stability, but the causality can be jeopardized by some modes. The unitary of the gauge sector is assured without any restriction , while the scalar sector is unitary only in the space-like case. (author)

Prospects for testing Lorentz and CPT symmetry with antiprotons.

Science.gov (United States)

Vargas, Arnaldo J

2018-03-28

A brief overview of the prospects of testing Lorentz and CPT symmetry with antimatter experiments is presented. The models discussed are applicable to atomic spectroscopy experiments, Penning-trap experiments and gravitational tests. Comments about the sensitivity of the most recent antimatter experiments to the models reviewed here are included.This article is part of the Theo Murphy meeting issue 'Antiproton physics in the ELENA era'. © 2018 The Author(s).

CPT symmetry and antimatter gravity in general relativity

Science.gov (United States)

Villata, M.

2011-04-01

The gravitational behavior of antimatter is still unknown. While we may be confident that antimatter is self-attractive, the interaction between matter and antimatter might be either attractive or repulsive. We investigate this issue on theoretical grounds. Starting from the CPT invariance of physical laws, we transform matter into antimatter in the equations of both electrodynamics and gravitation. In the former case, the result is the well-known change of sign of the electric charge. In the latter, we find that the gravitational interaction between matter and antimatter is a mutual repulsion, i.e. antigravity appears as a prediction of general relativity when CPT is applied. This result supports cosmological models attempting to explain the Universe accelerated expansion in terms of a matter-antimatter repulsive interaction.

Dimensional reduction of a Lorentz and CPT-violating Maxwell-Chern-Simons model

Energy Technology Data Exchange (ETDEWEB)

Belich, H. Jr.; Helayel Neto, J.A. [Centro Brasileiro de Pesquisas Fisicas (CBPF), Rio de Janeiro, RJ (Brazil). Coordenacao de Teoria de Campos e Particulas; Grupo de Fisica Teorica Jose Leite Lopes, Petropolis, RJ (Brazil); E-mails: belich@cbpf.br; helayel@cbpf.br; Ferreira, M.M. Jr. [Grupo de Fisica Teorica Jose Leite Lopes, Petropolis, RJ (Brazil); Maranhao Univ., Sao Luiz, MA (Brazil). Dept. de Fisica]. E-mail: manojr@cbpf.br; Orlando, M.T.D. [Grupo de Fisica Teorica Jose Leite Lopes, Petropolis, RJ (Brazil); Espirito Santo Univ., Vitoria, ES (Brazil). Dept. de Fisica e Quimica; E-mail: orlando@cce.ufes.br

2003-01-01

Taking as starting point a Lorentz and CPT non-invariant Chern-Simons-like model defined in 1+3 dimensions, we proceed realizing its dimensional to D = 1+2. One then obtains a new planar model, composed by the Maxwell-Chern-Simons (MCS) sector, a Klein-Gordon massless scalar field, and a coupling term that mixes the gauge field to the external vector, {nu}{sup {mu}}. In spite of breaking Lorentz invariance in the particle frame, this model may preserve the CPT symmetry for a single particular choice of {nu}{sup {mu}} . Analyzing the dispersion relations, one verifies that the reduced model exhibits stability, but the causality can be jeopardized by some modes. The unitary of the gauge sector is assured without any restriction , while the scalar sector is unitary only in the space-like case. (author)

Cosmology and CPT violating neutrinos

Energy Technology Data Exchange (ETDEWEB)

Barenboim, Gabriela; Salvado, Jordi [Universitat de Valencia-CSIC, Departament de Fisica Teorica y Instituto de Fisica Corpuscular, Burjassot (Spain)

2017-11-15

The combination charge conjugation-parity-time reversal (CPT) is a fundamental symmetry in our current understanding of nature. As such, testing CPT violation is a strongly motivated path to explore new physics. In this paper we study CPT violation in the neutrino sector, giving for the first time a bound, for a fundamental particle, in the CPT violating particle-antiparticle gravitational mass difference. We argue that cosmology is nowadays the only data sensitive to CPT violation for the neutrino-antineutrino mass splitting and we use the latest data release from Planck combined with the current baryonic-acoustic-oscillation measurement to perform a full cosmological analysis. To show the potential of the future experiments we also show the results for Euclid, a next generation large scale structure experiment. (orig.)

Test of CPT and Lorentz symmetry in entangled neutral kaons with the KLOE experiment

International Nuclear Information System (INIS)

Babusci, D.; Balwierz-Pytko, I.; Bencivenni, G.; Bloise, C.; Bossi, F.; Branchini, P.; Budano, A.; Caldeira Balkeståhl, L.; Capon, G.; Ceradini, F.; Ciambrone, P.; Curciarello, F.; Czerwiński, E.; Danè, E.; De Leo, V.; De Lucia, E.; De Robertis, G.; De Santis, A.; De Simone, P.

2014-01-01

Neutral kaon pairs produced in ϕ decays in anti-symmetric entangled state can be exploited to search for violation of CPT symmetry and Lorentz invariance. We present an analysis of the CP-violating process ϕ→K S K L →π + π − π + π − based on 1.7 fb −1 of data collected by the KLOE experiment at the Frascati ϕ-factory DAΦNE. The data are used to perform a measurement of the CPT-violating parameters Δa μ for neutral kaons in the context of the Standard Model Extension framework. The parameters measured in the reference frame of the fixed stars are: Δa 0 =(−6.0±7.7 stat ±3.1 syst )×10 −18 GeV, Δa X =(0.9±1.5 stat ±0.6 syst )×10 −18 GeV, Δa Y =(−2.0±1.5 stat ±0.5 syst )×10 −18 GeV, Δa Z =(3.1±1.7 stat ±0.5 syst )×10 −18 GeV. These are presently the most precise measurements in the quark sector of the Standard Model Extension.

Tests of quantum mechanics and CPT symmetry with experimental data from CPLEAR

CERN Document Server

Miller, J P; Apostolakis, Alcibiades J; Aslanides, Elie; Backenstoss, Gerhard; Bargassa, P; Behnke, O; Benelli, A; Bertin, V; Blanc, F; Bloch, P; Carlson, P J; Carroll, M; Carvalho, J; Cawley, E; Chertok, M B; Danielsson, M; Dejardin, M; Derré, J; Ealet, A; Eleftheriadis, C; Faravel, L; Fetscher, W; Fidecaro, Maria; Filipcic, A; Francis, D; Fry, J; Gabathuler, Erwin; Gamet, R; Gerber, H J; Go, A; Haselden, A; Hayman, P J; Henry-Coüannier, F; Hollander, R W; Jon-And, K; Kettle, P R; Kokkas, P; Kreuger, R; Le Gac, R; Leimgruber, F; Mandic, I; Manthos, N; Marel, Gérard; Mikuz, M; Miller, J; Montanet, François; Müller, A; Nakada, Tatsuya; Pagels, B; Papadopoulos, I M; Pavlopoulos, P; Polivka, G; Rickenbach, R; Roberts, B L; Ruf, T; Schäfer, M; Schaller, L A; Schietinger, T; Schopper, A; Tauscher, Ludwig; Thibault, C; Touchard, F; Touramanis, C; van Eijk, C W E; Vlachos, S; Weber, P; Wigger, O; Wolter, M; Zavrtanik, D; Zimmerman, D; Ellis, Jonathan Richard; López, J L; Mavromatos, Nikolaos E; Nanopoulos, Dimitri V

1999-01-01

Data from the CPLEAR experiment are used to test CPT violation outside of regular quantum mechanics. The test is based on a model, motivated by Hawking's notion of loss of quantum coherence across a microscopic event horizon, which was developed in a particular version of string theory. (5 refs).

Sensitivity of continuous performance test (CPT) at age 14years to developmental methylmercury exposure

DEFF Research Database (Denmark)

Julvez, Jordi; Debes, Frodi; Weihe, Pal

2010-01-01

Hit Reaction Time latencies (HRT) in the Continuous Performance Test (CPT) measure the speed of visual information processing. The latencies may involve different neuropsychological functions depending on the time from test initiation, i.e., first orientation, learning and habituation, then cogni......Hit Reaction Time latencies (HRT) in the Continuous Performance Test (CPT) measure the speed of visual information processing. The latencies may involve different neuropsychological functions depending on the time from test initiation, i.e., first orientation, learning and habituation......, then cognitive processing and focused attention, and finally sustained attention as the dominant demand. Prenatal methylmercury exposure is associated with increased reaction time (RT) latencies. We therefore examined the association of methylmercury exposure with the average HRT at age 14years at three...

TESTING CPT SYMMETRY WITH CURRENT AND FUTURE CMB MEASUREMENTS

Energy Technology Data Exchange (ETDEWEB)

Li, Si-Yu; Zhang, Xinmin [Theory Division, Institute of High Energy Physics, Chinese Academy of Science, P.O. Box 918-4, Beijing 100049 (China); Xia, Jun-Qing; Li, Hong [Key Laboratory of Particle Astrophysics, Institute of High Energy Physics, Chinese Academy of Science, P.O. Box 918-3, Beijing 100049 (China); Li, Mingzhe, E-mail: xiajq@ihep.ac.cn [Interdisciplinary Center for Theoretical Study, University of Science and Technology of China, Hefei, Anhui 230026 (China)

2015-02-01

In this paper, we use the current and future cosmic microwave background (CMB) experiments to test the Charge-Parity-Time Reversal (CPT) symmetry. We consider a CPT-violating interaction in the photon sector L{sub cs}∼p{sub μ}A{sub ν} F-tilde {sup μν}, which gives rise to a rotation of the polarization vectors of the propagating CMB photons. By combining the 9 yr WMAP, BOOMERanG 2003, and BICEP1 observations, we obtain the current constraint on the isotropic rotation angle α-bar =−2.12±1.14 (1σ), indicating that the significance of the CPT violation is about 2σ. Here, we particularly take the systematic errors of CMB measurements into account. Then, we study the effects of the anisotropies of the rotation angle [Δα( n-hat )] on the CMB polarization power spectra in detail. Due to the small effects, the current CMB polarization data cannot constrain the related parameters very well. We obtain the 95% C.L. upper limit of the variance of the anisotropies of the rotation angle C {sup α}(0) < 0.035 from all of the CMB data sets. More interestingly, including the anisotropies of rotation angle could lower the best-fit value of r and relax the tension on the constraints of r between BICEP2 and Planck. Finally, we investigate the capabilities of future Planck polarization measurements on α-bar and Δα( n-hat ). Benefited from the high precision of Planck data, the constraints of the rotation angle can be significantly improved.

Cone penetrometer testing (CPT) for groundwater contamination

International Nuclear Information System (INIS)

Jordan, J.E.; Van Pelt, R.S.

1993-01-01

Over the past decade, researchers at the Savannah River Site (SRS) and elsewhere have greatly advanced the knowledge of waste site characterization technologies. As a result, many of the techniques used in the past to investigate waste sites have been replaced by newer technologies, designed to provide greater protection for human health and the environment, greater access to suspected zones of contamination, and more accurate information of subsurface conditions. Determining the most environmentally sound method of assessing a waste unit is a major component of the SRS environmental restoration program. In an effort to understand the distribution and migration of contaminants in the groundwater system, the cone penetrometer investigation of the A/M-Area Southern Sector was implemented. The program incorporated a phased approach toward characterization by first using the CPT to delineate the plume boundary, followed by installing groundwater monitoring wells. The study provided the additional hydrogeologic information necessary to better understand the nature and extent of the contaminant plume (Fig. 1) and the hydrogeologic system in the Southem Sector. This data is essential for the optimal layout of the planned groundwater monitoring well network and recovery system to remediate the aquifers in the area. A number of other test locations were selected in the area during this study for lithologic calibration of the tool and to collect confirmation water samples from the aquifer. Cone penetrometer testing and hydrocone sampling, were performed at 17 sites (Fig. 2). The hydrocone, a tool modification to the CPT, was used to collect four groundwater samples from confined aquifers. These samples were analyzed by SRS laboratories. Elevated levels of chlorinated compounds were detected from these samples and have aided in further delineating the southern sector contaminant plume

Test of CPT and Lorentz symmetry in entangled neutral kaons with the KLOE experiment

Energy Technology Data Exchange (ETDEWEB)

Babusci, D. [Laboratori Nazionali di Frascati dell' INFN, Frascati (Italy); Balwierz-Pytko, I. [Institute of Physics, Jagiellonian University, Cracow (Poland); Bencivenni, G.; Bloise, C.; Bossi, F. [Laboratori Nazionali di Frascati dell' INFN, Frascati (Italy); Branchini, P. [INFN Sezione di Roma Tre, Roma (Italy); Budano, A. [Dipartimento di Matematica e Fisica dell' Università “Roma Tre”, Roma (Italy); INFN Sezione di Roma Tre, Roma (Italy); Caldeira Balkeståhl, L. [Department of Physics and Astronomy, Uppsala University, Uppsala (Sweden); Capon, G. [Laboratori Nazionali di Frascati dell' INFN, Frascati (Italy); Ceradini, F. [Dipartimento di Matematica e Fisica dell' Università “Roma Tre”, Roma (Italy); INFN Sezione di Roma Tre, Roma (Italy); Ciambrone, P. [Laboratori Nazionali di Frascati dell' INFN, Frascati (Italy); Curciarello, F. [Dipartimento di Fisica e Scienze della Terra dell' Università di Messina, Messina (Italy); INFN Sezione di Catania, Catania (Italy); Czerwiński, E. [Institute of Physics, Jagiellonian University, Cracow (Poland); Danè, E. [Laboratori Nazionali di Frascati dell' INFN, Frascati (Italy); De Leo, V. [Dipartimento di Fisica e Scienze della Terra dell' Università di Messina, Messina (Italy); INFN Sezione di Catania, Catania (Italy); De Lucia, E. [Laboratori Nazionali di Frascati dell' INFN, Frascati (Italy); De Robertis, G. [INFN Sezione di Bari, Bari (Italy); De Santis, A., E-mail: antonio.desantis@roma1.infn.it [Dipartimento di Fisica dell' Università “Sapienza”, Roma (Italy); INFN Sezione di Roma, Roma (Italy); De Simone, P. [Laboratori Nazionali di Frascati dell' INFN, Frascati (Italy); and others

2014-03-07

Neutral kaon pairs produced in ϕ decays in anti-symmetric entangled state can be exploited to search for violation of CPT symmetry and Lorentz invariance. We present an analysis of the CP-violating process ϕ→K{sub S}K{sub L}→π{sup +}π{sup −}π{sup +}π{sup −} based on 1.7 fb{sup −1} of data collected by the KLOE experiment at the Frascati ϕ-factory DAΦNE. The data are used to perform a measurement of the CPT-violating parameters Δa{sub μ} for neutral kaons in the context of the Standard Model Extension framework. The parameters measured in the reference frame of the fixed stars are: Δa{sub 0}=(−6.0±7.7{sub stat}±3.1{sub syst})×10{sup −18} GeV, Δa{sub X}=(0.9±1.5{sub stat}±0.6{sub syst})×10{sup −18} GeV, Δa{sub Y}=(−2.0±1.5{sub stat}±0.5{sub syst})×10{sup −18} GeV, Δa{sub Z}=(3.1±1.7{sub stat}±0.5{sub syst})×10{sup −18} GeV. These are presently the most precise measurements in the quark sector of the Standard Model Extension.

Strong equivalence, Lorentz and CPT violation, anti-hydrogen spectroscopy and gamma-ray burst polarimetry

International Nuclear Information System (INIS)

Shore, Graham M.

2005-01-01

The strong equivalence principle, local Lorentz invariance and CPT symmetry are fundamental ingredients of the quantum field theories used to describe elementary particle physics. Nevertheless, each may be violated by simple modifications to the dynamics while apparently preserving the essential fundamental structure of quantum field theory itself. In this paper, we analyse the construction of strong equivalence, Lorentz and CPT violating Lagrangians for QED and review and propose some experimental tests in the fields of astrophysical polarimetry and precision atomic spectroscopy. In particular, modifications of the Maxwell action predict a birefringent rotation of the direction of linearly polarised radiation from synchrotron emission which may be studied using radio galaxies or, potentially, gamma-ray bursts. In the Dirac sector, changes in atomic energy levels are predicted which may be probed in precision spectroscopy of hydrogen and anti-hydrogen atoms, notably in the Doppler-free, two-photon 1s-2s and 2s-nd (n∼10) transitions

Gravity, CPT, and the standard-model extension

Energy Technology Data Exchange (ETDEWEB)

Tasson, Jay D., E-mail: tasson1@stolaf.edu [St. Olaf College (United States)

2015-08-15

Exotic atoms provide unique opportunities to search for new physics. The search for CPT and Lorentz violation in the context of the general field-theory based framework of the gravitational Standard-Model Extension (SME) is one such opportunity. This work summarizes the implications of Lorentz and CPT violation for gravitational experiments with antiatoms and atoms containing higher-generation matter as well as recent nongravitational proposals to test CPT and Lorentz symmetry with muons and muonic systems.

Experimental tests of CP, T and CPT symmetries using K0 and K-bar0

International Nuclear Information System (INIS)

Zavrtanik, D.; Angelopoulos, A.; Apostolakis, A.; Aslanides, E.; Bertin, V.; Ealet, A.; Fassnacht, P.; Henry-Couannier, F.; Le Gac, R.; Montanet, F.; Touchard, F.; Backenstoss, G.; Leimgruber, F.; Pavlopoulos, P.; Polivka, G.; Rickenbach, R.; Schietinger, T.; Tauscher, L.; Vlachos, S.; Bargassa, P.

1998-01-01

The CPLEAR experiment at CERN measured the CP and CPT violation parameters and determined in a direct way the T violation. The results allow the determination of the CPT violation parameters in the neutral kaon mixing with a precision better than a few 10 -4 . The mass equality between K 0 and K-tilde 0 is tested down to the level of 10 -19 GeV. In addition, physics on a scale close to the Planck mass is probed for the first time

Extension of the CPT theorem to non-Hermitian Hamiltonians and unstable states

Energy Technology Data Exchange (ETDEWEB)

Mannheim, Philip D., E-mail: philip.mannheim@uconn.edu

2016-02-10

We extend the CPT theorem to quantum field theories with non-Hermitian Hamiltonians and unstable states. Our derivation is a quite minimal one as it requires only the time-independent evolution of scalar products, invariance under complex Lorentz transformations, and a non-standard but nonetheless perfectly legitimate interpretation of charge conjugation as an antilinear operator. The first of these requirements does not force the Hamiltonian to be Hermitian. Rather, it forces its eigenvalues to either be real or to appear in complex conjugate pairs, forces the eigenvectors of such conjugate pairs to be conjugates of each other, and forces the Hamiltonian to admit of an antilinear symmetry. The latter two requirements then force this antilinear symmetry to be CPT, while forcing the Hamiltonian to be real rather than Hermitian. Our work justifies the use of the CPT theorem in establishing the equality of the lifetimes of unstable particles that are charge conjugates of each other. We show that the Euclidean time path integrals of a CPT-symmetric theory must always be real. In the quantum-mechanical limit the key results of the PT symmetry program of Bender and collaborators are recovered, with the C-operator of the PT symmetry program being identified with the linear component of the charge conjugation operator.

Testing CPT conservation using the NuMI neutrino beam with the MINOS experiment

Energy Technology Data Exchange (ETDEWEB)

Auty, David John [Univ. of Sussex, Brighton (United Kingdom)

2010-03-01

The MINOS experiment was designed to measure neutrino oscillation parameters with muon neutrinos. It achieves this by measuring the neutrino energy spectrum and flavor composition of the man-made NuMI neutrino beam 1km after the beam is formed and again after 735 km. By comparing the two spectra it is possible to measure the oscillation parameters. The NuMI beam is made up of 7.0%$\\bar{v}$_μ, which can be separated from the v_μ because the MINOS detectors are magnetized. This makes it possible to study $\\bar{v}$_μ oscillations separately from those of muon neutrinos, and thereby test CPT invariance in the neutrino sector by determining the $\\bar{v}$_μ oscillation parameters and comparing them with those for v_μ, although any unknown physics of the antineutrino would appear as a difference in oscillation parameters. Such a test has not been performed with beam $\\bar{v}$_μ before. It is also possible to produce an almost pure $\\bar{v}$_μ beam by reversing the current through the magnetic focusing horns of the NuMI beamline, thereby focusing negatively, instead of positively charged particles. This thesis describes the analysis of the 7% $\\bar{v}$_μ component of the forward horn current NuMI beam. The $\\bar{v}$_μ of a data sample of 3.2 x 10{sup 20} protons on target analysis found 42 events, compared to a CPT conserving prediction of 58.3_-7.6^+7.6(stat.)_-3.6^+3.6(syst.) events. This corresponds to a 1.9 σ deficit, and a best fit value of Δ$\\bar{m}$₃₂² = 18 x 10^-3 eV² and sin² 2$\\bar{θ}$₂₃ = 0.55. This thesis focuses particularly on the selection of $\\bar{v}$_μ events, and investigates possible improvements of the selection algorithm. From this a different selector was chosen, which corroborated the findings of the original selector. The

CPT and superstring

International Nuclear Information System (INIS)

Ellis, J.; Mavromatos, N.E.; Nanopoulos, D.V.

1996-07-01

The authors discuss the possibility that CPT violation may appear as a consequence of microscopic decoherence due to quantum-gravity effects, that they describe using a density-matrix formalism motivated by their studies of non-critical string theory. The maximum possible order of magnitude of such decohering CPT-violating effects is not far from the sensitivity of present experiments on the neutral kaon system, and they review a simple parametrization for them. The authors also review a recent data analysis carried out together with the CPLEAR collaboration, which bounds any such decohering CPT-violating parameters to be approx-lt 10 -19 GeV

CP, T, and CPT violation in the neutral kaon system at the CPLEAR experiment

CERN Document Server

Adler, R; Angelopoulos, Angelos; Aslanides, Elie; Backenstoss, Gerhard; Bee, C P; Behnke, O; Bennet, J; Bertin, V; Blanc, F; Bloch, P; Bula, C; Carlson, P J; Carroll, M; Carvalho, J; Cawley, E; Charalambous, S; Chardalas, M; Chardin, G; Chertok, M B; Cody, A; Danielsson, M; Dedoussis, S; Dejardin, M; Derré, J; Dodgson, M; Duclos, J; Ealet, A; Eckart, B; Eleftheriadis, C; Evangelou, I; Faravel, L; Fassnacht, P; Faure, J L; Felder, C; Ferreira-Marques, R; Fetscher, W; Fidecaro, Maria; Filipcic, A; Francis, D; Fry, J; Gabathuler, Erwin; Gamet, R; Garreta, D; Geralis, T; Gerber, H J; Gumplinger, P; Go, A; Guyot, C; Haselden, A; Hayman, P J; Henry-Coüannier, F; Hollander, R W; Hubert, E; Jansson, K; Johner, H U; Jon-And, K; Kettle, P R; Kochowski, Claude; Kokkas, P; Kreuger, R; Lawry, T; Le Gac, R; Leimgruber, F; Liolios, A; Machado, E; Maley, P; Mandic, I; Manthos, N; Marel, Gérard; Mikuz, M; Miller, J; Montanet, François; Nakada, Tatsuya; Onofre, A; Pagels, B; Pavlopoulos, P; Pelucchi, F; Pinto da Cunha, J; Policarpo, Armando; Polivka, G; Postma, H; Rickenbach, R; Roberts, B L; Rozaki, E; Ruf, T; Sacks, L; Sakelliou, L; Sanders, P; Santoni, C; Sarigiannis, K; Schäfer, M; Schaller, L A; Schopper, A; Schune, P; Soares, A; Tauscher, Ludwig; Thibault, C; Touchard, F; Touramanis, C; Triantis, F A; Tröster, D A; Van Beveren, E; van Eijk, C W E; Vlachos, S; Weber, P; Wigger, O; Witzig, C; Wolter, M; Yéche, C; Zavrtanik, D; Zimmerman, D

1996-01-01

The essential characteristics of the neutral kaon system and the way CP, T, and possible CPT violations may be observed in it are recalled. The principle of the CPLEAH experiment is presented CPLEAH experimental results in the semi-leptonic decay channels are given and discussed. It is shown, in particular, that direct. time reversal invariance violation will be experimentally observed for the first time.

Fundamental symmetry tests with antihydrogen

International Nuclear Information System (INIS)

Hughes, R.J.

1992-01-01

The prospects for testing CPT invariance and the weak equivalence principle (WEP) for antimatter with spectroscopic measurements on antihydrogen are discussed. The potential precisions of these tests are compared with those from other measurements. The arguments involving energy conservation, the behavior of neutral kaons in a gravitational field and the equivalence principle for antiparticles are reviewed in detail

Maturational delay in ADHD: Evidence from CPT

Directory of Open Access Journals (Sweden)

Itai eBerger

2013-10-01

Full Text Available While data from behavioural, neuropsychological, and brain studies suggested that Attention-Deficit/Hyperactivity Disorder (ADHD is related to a developmental lag that reduces with age, other studies have proposed that ADHD represents a deviant brain function. The present study used a cross-sectional approach to examine whether ADHD children show a developmental delay in cognitive performance measured by continuous performance test (CPT. We thus compared six age groups of ADHD children (N=559 and their unaffected peers (N=365, aged 6-11, in four parameters of MOXO-CPT performance: Attention, Timing, Hyperactivity and Impulsivity. Results have shown that despite improvement in CPT performance with age, ADHD children continued to demonstrate impaired performance as compared to controls. In most parameters, CPT performance of ADHD children matched that of 1-3 years younger normal controls, with a delay most prominent in older children. However, in the Hyperactivity parameter, ADHD children’s performance resembled that of much younger healthy children, with almost no evidence for a developmental catch up. This study suggests that while some cognitive functions develop slower but normally, other functions (e.g., inhibitory control show a different sequel.

Revisiting measurement invariance in intelligence testing in aging research: Evidence for almost complete metric invariance across age groups.

Science.gov (United States)

Sprague, Briana N; Hyun, Jinshil; Molenaar, Peter C M

2017-01-01

Invariance of intelligence across age is often assumed but infrequently explicitly tested. Horn and McArdle (1992) tested measurement invariance of intelligence, providing adequate model fit but might not consider all relevant aspects such as sub-test differences. The goal of the current paper is to explore age-related invariance of the WAIS-R using an alternative model that allows direct tests of age on WAIS-R subtests. Cross-sectional data on 940 participants aged 16-75 from the WAIS-R normative values were used. Subtests examined were information, comprehension, similarities, vocabulary, picture completion, block design, picture arrangement, and object assembly. The two intelligence factors considered were fluid and crystallized intelligence. Self-reported ages were divided into young (16-22, n = 300), adult (29-39, n = 275), middle (40-60, n = 205), and older (61-75, n = 160) adult groups. Results suggested partial metric invariance holds. Although most of the subtests reflected fluid and crystalized intelligence similarly across different ages, invariance did not hold for block design on fluid intelligence and picture arrangement on crystallized intelligence for older adults. Additionally, there was evidence of a correlated residual between information and vocabulary for the young adults only. This partial metric invariance model yielded acceptable model fit compared to previously-proposed invariance models of Horn and McArdle (1992). Almost complete metric invariance holds for a two-factor model of intelligence. Most of the subtests were invariant across age groups, suggesting little evidence for age-related bias in the WAIS-R. However, we did find unique relationships between two subtests and intelligence. Future studies should examine age-related differences in subtests when testing measurement invariance in intelligence.

Sixth Meeting on CPT and Lorentz Symmetry

CERN Document Server

CPT and Lorentz Symmetry

2014-01-01

This book contains the Proceedings of the Sixth Meeting on CPT and Lorentz Symmetry, held at Indiana University in Bloomington on June 17–21, 2013. The Meeting focused on tests of these fundamental symmetries and on related theoretical issues, including scenarios for possible violations. Topics covered at the meeting include searches for CPT and Lorentz violations involving: accelerator and collider experiments; atomic, nuclear, and particle decays; birefringence, dispersion, and anisotropy in cosmological sources; clock-comparison measurements; electromagnetic resonant cavities and lasers; tests of the equivalence principle; gauge and Higgs particles; high-energy astrophysical observations; laboratory tests of gravity; matter interferometry; neutrino oscillations and propagation; oscillations and decays of neutral mesons; particle–antiparticle comparisons; post-newtonian gravity in the solar system and beyond; second- and third-generation particles; space-based missions; spectroscopy of hydrogen and ant...

Extracting rephase-invariant CP and CPT violating parameters from asymmetries of time-ordered integrated rates of correlated decays of entangled mesons

International Nuclear Information System (INIS)

Huang, Zhijie; Shi, Yu.

2012-01-01

We present a general model-independent formalism of measuring CP and CPT violating parameters through time-ordered integrated rates of correlated decays of C=±1 entangled states of neutral pseudoscalar mesons. We give the general formulae of CP and CPT violating parameters in terms of four measurable asymmetries defined for the time-ordered integrated rates, applicable to all kinds of decay product. Two special cases which are often realized in experiments are discussed specifically. (orig.)

Virtual-reality-based attention assessment of ADHD: ClinicaVR: Classroom-CPT versus a traditional continuous performance test.

Science.gov (United States)

Neguț, Alexandra; Jurma, Anda Maria; David, Daniel

2017-08-01

Virtual-reality-based assessment may be a good alternative to classical or computerized neuropsychological assessment due to increased ecological validity. ClinicaVR: Classroom-CPT (VC) is a neuropsychological test embedded in virtual reality that is designed to assess attention deficits in children with attention deficit hyperactivity disorder (ADHD) or other conditions associated with impaired attention. The present study aimed to (1) investigate the diagnostic validity of VC in comparison to a traditional continuous performance test (CPT), (2) explore the task difficulty of VC, (3) address the effect of distractors on the performance of ADHD participants and typically-developing (TD) controls, and (4) compare the two measures on cognitive absorption. A total of 33 children diagnosed with ADHD and 42 TD children, aged between 7 and 13 years, participated in the study and were tested with a traditional CPT or with VC, along with several cognitive measures and an adapted version of the Cognitive Absorption Scale. A mixed multivariate analysis of covariance (MANCOVA) revealed that the children with ADHD performed worse on correct responses had more commissions and omissions errors than the TD children, as well as slower target reaction times . The results showed significant differences between performance in the virtual environment and the traditional computerized one, with longer reaction times in virtual reality. The data analysis highlighted the negative influence of auditory distractors on attention performance in the case of the children with ADHD, but not for the TD children. Finally, the two measures did not differ on the cognitive absorption perceived by the children.

Status of CP and CPT violation in the neutral kaon system

CERN Document Server

Ruf, T

1996-01-01

A phenomenological description of the neutral-kaon system is presented without assuming \\CPT\\ conservation. The experimental methods and the underlying assumptions used to determine parameters of the neutral-kaon system (\\CP-violating and non \\CP-violating ones) are discussed. The experimental results are combined to test \\CPT\\ conservation with as little prejudice as possible.

Therapeutic Targeting of CPT-11 Induced Diarrhea: A Case for Prophylaxis

Science.gov (United States)

Swami, Umang; Goel, Sanjay; Mani, Sridhar

2014-01-01

CPT-11 (irinotecan), a DNA topoisomerase I inhibitor is one of the main treatments for colorectal cancer. The main dose limiting toxicities are neutropenia and late onset diarrhea. Though neutropenia is manageable, CPT-11 induced diarrhea is frequently severe, resulting in hospitalizations, dose reductions or omissions leading to ineffective treatment administration. Many potential agents have been tested in preclinical and clinical studies to prevent or ameliorate CPT-11 induced late onset diarrhea. It is predicted that prophylaxis of CPT-11 induced diarrhea will reduce sub-therapeutic dosing as well as hospitalizations and will eventually lead to dose escalations resulting in better response rates. This article reviews various experimental agents and strategies employed to prevent this debilitating toxicity. Covered topics include schedule/dose modification, intestinal alkalization, structural/chemical modification, genetic testing, anti-diarrheal therapies, transporter (ABCB1, ABCC2, BCRP2) inhibitors, enzyme (β-glucuronidase, UGT1A1, CYP3A4, carboxylesterase, COX-2) inducers and inhibitors, probiotics, antibiotics, adsorbing agents, cytokine and growth factor activators and inhibitors and other miscellaneous agents. PMID:23597015

Lorentz- and CPT-symmetry studies in subatomic physics

Energy Technology Data Exchange (ETDEWEB)

Lehnert, Ralf, E-mail: ralehner@indiana.edu [Leibniz Universität Hannover (Germany)

2016-12-15

Subatomic systems provide an exquisite test bench for spacetime symmetries. This work motivates such measurements, reviews the effective field theory test framework for the description of Lorentz and CPT violation, and employs this framework to study the phenomenology of spacetime-symmetry breaking in various subatomic systems.

Prospects for Lorentz and CPT tests with hydrogen and antihydrogen

CERN Document Server

Becker, Tobias Frederic

2017-01-01

As a summer student for 13 weeks in the ASACUSA-CUSP collaboration, under the supervision of Chloé Malbrunot, my project consisted in a first part on the theoretical treatment of Lorentz and CPT violation in hydrogen & antihydrogen in the framework of the Standard Model Extension SME and in second part on experimental measurements on a hydrogen beam.

Search for violation of CPT and Lorentz invariance in B.sup.0./sup..sub.s./sub. meson oscillations

Czech Academy of Sciences Publication Activity Database

Abazov, V. M.; Abbott, B.; Acharya, B.S.; Kupčo, Alexander; Lokajíček, Miloš

2015-01-01

Roč. 115, č. 16 (2015), "161601-1"-"161601-8" ISSN 0031-9007 Institutional support: RVO:68378271 Keywords : Batavia TEVATRON Coll * DZERO * asymmetry * anti -p p * scattering * B/s0 anti -B/s0: mixing * CPT * violation * experimental results Subject RIV: BF - Elementary Particles and High Energy Physics Impact factor: 7.645, year: 2015

A test of conformal invariance: Correlation functions on a disk

International Nuclear Information System (INIS)

Badke, R.; Rittenberg, V.; Ruegg, H.

1985-06-01

Using conformal invariance one can derive the correlation functions of a disk from those in the half-plane. The correlation function in the half-plane is determined by the 'small' conformal invariance up to an unknown function of one variable. By measuring through the Monte Carlo method the correlation function for two different configurations, the unknown function can be eliminated and one obtains a test of conformal invariance. It is shown that the Ising and the three state Potts model pass the test for very small lattices. (orig.)

One Antimatter— Two Possible Thermodynamics

Directory of Open Access Journals (Sweden)

Alexander Y. Klimenko

2014-02-01

Full Text Available Conventional thermodynamics, which is formulated for our world populated by radiation and matter, can be extended to describe physical properties of antimatter in two mutually exclusive ways: CP-invariant or CPT-invariant. Here we refer to invariance of physical laws under charge (C, parity (P and time reversal (T transformations. While in quantum field theory CPT invariance is a theorem confirmed by experiments, the symmetry principles applied to macroscopic phenomena or to the whole of the Universe represent only hypotheses. Since both versions of thermodynamics are different only in their treatment of antimatter, but are the same in describing our world dominated by matter, making a clear experimentally justified choice between CP invariance and CPT invariance in context of thermodynamics is not possible at present. This work investigates the comparative properties of the CP- and CPT-invariant extensions of thermodynamics (focusing on the latter, which is less conventional than the former and examines conditions under which these extensions can be experimentally tested.

Determining the potential independent critical pitting temperature (CPT) by a potentiostatic method using the Avesta Cell

International Nuclear Information System (INIS)

Arnvig, P.E.; Bisgard, A.D.

1996-01-01

The development of a potentiostatic method for determining the potential independent Critical Pitting Temperature (CPT) using the Avesta Cell is presented. The new potentiostatic method has been used to determine the CPT for austenitic stainless steels. The precision of the potentiostatic method of approximately ±2 C is close to that of the traditional potentiodynamic method. The time required to determine a CPT is much shorter than when using the potentiodynamic method. A CPT is obtained within 1.5 to 3 hours for each specimen. The influence of various experimental parameters such as electrochemical potential, evaluation criteria for the CPT, test area, stabilization time prior to polarization and inert gas purging is described. The lack of sensitivity towards many of these parameters as well as the high reproducibility obtained is associated with fundamentals of the pitting process. It is argued that the potential independent CPT characterizes the stable propagating pitting event as opposed to the potential dependent CPT or pitting potentials, which to a larger extent are affected by the nucleation part of the pitting process

A phenomenological study of violation of CP and CPT symmetries in the neutral kaon system

International Nuclear Information System (INIS)

Kojima, Kazushi; Sugiyama, Wataru; Tsai, S.Y.

1996-01-01

A phenomenological study is given of the (possible) violation of CP and CPT symmetries in the K 0 -K-bar 0 system. Special attention is paid to the problem of phase ambiguity and phase convention. Mixing parameters and decay amplitudes are parametrized in a rephasing invariant way, and the well-known parameters η +- and η 00 describing 2π modes as well as various leptonic asymmetries are expressed in terms of these parameters. The parameters ε and Δ characterizing mixing between |K 0 > and |K-bar 0 > are treated with as little theoretical prejudice as possible. (author)

Probing CPT violation with CMB polarization measurements

Energy Technology Data Exchange (ETDEWEB)

Xia Junqing, E-mail: xia@sissa.i [Scuola Internazionale Superiore di Studi Avanzati, Via Beirut 2-4, I-34014 Trieste (Italy); Li Hong; Zhang Xinmin [Institute of High Energy Physics, Chinese Academy of Science, P.O. Box 918-4, Beijing 100049 (China); Theoretical Physics Center for Science Facilities (TPCSF), Chinese Academy of Science (China)

2010-04-12

The electrodynamics modified by the Chern-Simons term L{sub cs}approxp{sub m}uA{sub n}uF-tilde{sup m}u{sup n}u with a non-vanishing p{sub m}u violates the Charge-Parity-Time Reversal symmetry (CPT) and rotates the linear polarizations of the propagating Cosmic Microwave Background (CMB) photons. In this Letter we measure the rotation angle DELTAalpha by performing a global analysis on the current CMB polarization measurements from the five-year Wilkinson Microwave Anisotropy Probe (WMAP5), BOOMERanG 2003 (B03), BICEP and QUaD using a Markov Chain Monte Carlo method. Neglecting the systematic errors of these experiments, we find that the results from WMAP5, B03 and BICEP all are consistent and their combination gives DELTAalpha=-2.62+-0.87deg (68% C.L.), indicating a 3sigma detection of the CPT violation. The QUaD data alone gives DELTAalpha=0.59+-0.42deg (68% C.L.) which has an opposite sign for the central value and smaller error bar compared to that obtained from WMAP5, B03 and BICEP. When combining all the polarization data together, we find DELTAalpha=0.09+-0.36deg (68% C.L.) which significantly improves the previous constraint on DELTAalpha and test the validity of the fundamental CPT symmetry at a higher level.

Measuring Undrained Shear Strength using CPT and Field Vane

DEFF Research Database (Denmark)

Luke, Kirsten

1992-01-01

This paper presents the results of CPT's and Field Vane tests from two small test areas with different soils, Glacial Till and Yoldia Clay. An average of Nk = qt/cv for the Yoldia Clay is 7.7 with a standard deviation of 0.7. The average of Nk for the Glacial Till is 9.7 with a standard deviation...

Crystal Structure of Rat Carnitine Palmitoyltransferase II (CPT-II)

Energy Technology Data Exchange (ETDEWEB)

Hsiao,Y.; Jogl, G.; Esser, V.; Tong, L.

2006-01-01

Carnitine palmitoyltransferase II (CPT-II) has a crucial role in the {beta}-oxidation of long-chain fatty acids in mitochondria. We report here the crystal structure of rat CPT-II at 1.9 Angstroms resolution. The overall structure shares strong similarity to those of short- and medium-chain carnitine acyltransferases, although detailed structural differences in the active site region have a significant impact on the substrate selectivity of CPT-II. Three aliphatic chains, possibly from a detergent that is used for the crystallization, were found in the structure. Two of them are located in the carnitine and CoA binding sites, respectively. The third aliphatic chain may mimic the long-chain acyl group in the substrate of CPT-II. The binding site for this aliphatic chain does not exist in the short- and medium-chain carnitine acyltransferases, due to conformational differences among the enzymes. A unique insert in CPT-II is positioned on the surface of the enzyme, with a highly hydrophobic surface. It is likely that this surface patch mediates the association of CPT-II with the inner membrane of the mitochondria.

Improved test of Lorentz invariance in electrodynamics

International Nuclear Information System (INIS)

Wolf, Peter; Bize, Sebastien; Clairon, Andre; Santarelli, Giorgio; Tobar, Michael E.; Luiten, Andre N.

2004-01-01

We report new results of a test of Lorentz invariance based on the comparison of a cryogenic sapphire microwave resonator and a hydrogen-maser. The experimental results are shown together with an extensive analysis of systematic effects. Previously, this experiment has set the most stringent constraint on Kennedy-Thorndike type violations of Lorentz invariance. In this work we present new data and interpret our results in the general Lorentz violating extension of the standard model of particle physics (SME). Within the photon sector of the SME, our experiment is sensitive to seven SME parameters. We marginally improve present limits on four of these, and by a factor seven to ten on the other three

Experimental prospects for C, P, T, CP, and CPT tests

International Nuclear Information System (INIS)

Bevan, Adrian

2015-01-01

Discrete symmetry violation in the weak interaction is central to the Standard Model of particle physics, however the origin of these violations is not well understood. Nor are we able to provide a satisfactory explanation of the Universal dominance of matter over antimatter, an issue related to CP violation. As a result study of discrete symmetry violation remains a topic of broad interest. These proceedings discuss experimental prospects of studying C, P, T, CP and CPT symmetries in a number of contexts, including the use of triple product asymmetries and entangled neutral meson systems. (paper)

Models & Searches of CPT Violation: a personal, very partial, list

Directory of Open Access Journals (Sweden)

Mavromatos Nick E.

2018-01-01

Full Text Available In this talk, first I motivate theoretically, and then I review the phenomenology of, some models entailing CPT Violation (CPTV. The latter is argued to be responsible for the observed matter-antimatter asymmetry in the Cosmos, and may owe its origin to either Lorentz-violating background geometries, whose effects are strong in early epochs of the Universe but very weak today, being temperature dependent in general, or to an ill-defined CPT generator in some quantum gravity models entailing decoherence of quantum matter as a result of quantum degrees of freedom in the gravity sector that are inaccessible to the low-energy observers. In particular, for the latter category of CPTV, I argue that entangled states of neutral mesons (Kaons or B-systems, of central relevance to KLOE-2 experiment, can provide smoking-gun sensitive tests or even falsify some of these models. If CPT is ill-defined one may also encounter violations of the spin-statistics theorem, with possible consequences for the Pauli Exclusion Principle, which I only briefly touch upon.

Models & Searches of CPT Violation: a personal, very partial, list

Science.gov (United States)

Mavromatos, Nick E.

2018-01-01

In this talk, first I motivate theoretically, and then I review the phenomenology of, some models entailing CPT Violation (CPTV). The latter is argued to be responsible for the observed matter-antimatter asymmetry in the Cosmos, and may owe its origin to either Lorentz-violating background geometries, whose effects are strong in early epochs of the Universe but very weak today, being temperature dependent in general, or to an ill-defined CPT generator in some quantum gravity models entailing decoherence of quantum matter as a result of quantum degrees of freedom in the gravity sector that are inaccessible to the low-energy observers. In particular, for the latter category of CPTV, I argue that entangled states of neutral mesons (Kaons or B-systems), of central relevance to KLOE-2 experiment, can provide smoking-gun sensitive tests or even falsify some of these models. If CPT is ill-defined one may also encounter violations of the spin-statistics theorem, with possible consequences for the Pauli Exclusion Principle, which I only briefly touch upon.

T-violation and CPT-invariance measurements in the CPLEAR experiment: a detailed description of the analysis of neutral-kaon decays to eπν

International Nuclear Information System (INIS)

Angelopoulos, A.; Aslanides, E.; Backenstoss, G.

2001-01-01

A detailed description of the analysis of neutral kaons decaying to eπν is given, based on the complete set of data collected with the CPLEAR experiment. Using a novel approach involving initially strangeness-tagged K 0 and K 0 , time-dependent decay-rate asymmetries were measured. These asymmetries enabled T- and CPT-violation parameters to be measured in the context of a systematic study. The highlights of this study are the first direct observation of T violation and the direct determination of the CPT parameter Re(δ) with an accuracy improved by two orders of magnitude with respect to the current value. (orig.)

Concerning tests of time-reversal invariance via the polarization-analyzing power equality

International Nuclear Information System (INIS)

Conzett, H.E.

1982-01-01

Previous tests of time-reversal invariance via comparisons of polarizations and analyzing powers in nuclear scattering have been examined. It is found that all of these comparisons fail as adequate tests of time-reversal invariance either because of a lack of experimental precision or the lack of sensitivity to any time-reversal symmetry violation

Test of charge conjugation invariance

International Nuclear Information System (INIS)

Nefkens, B.M.K.; Prakhov, S.; Gaardestig, A.; Clajus, M.; Marusic, A.; McDonald, S.; Phaisangittisakul, N.; Price, J.W.; Starostin, A.; Tippens, W.B.; Allgower, C.E.; Spinka, H.; Bekrenev, V.; Koulbardis, A.; Kozlenko, N.; Kruglov, S.; Lopatin, I.; Briscoe, W.J.; Shafi, A.; Comfort, J.R.

2005-01-01

We report on the first determination of upper limits on the branching ratio (BR) of η decay to π 0 π 0 γ and to π 0 π 0 π 0 γ. Both decay modes are strictly forbidden by charge conjugation (C) invariance. Using the Crystal Ball multiphoton detector, we obtained BR(η→π 0 π 0 γ) -4 at the 90% confidence level, in support of C invariance of isoscalar electromagnetic interactions of the light quarks. We have also measured BR(η→π 0 π 0 π 0 γ) -5 at the 90% confidence level, in support of C invariance of isovector electromagnetic interactions

An experimental test of CPT conservation in decays of neutral kaons

International Nuclear Information System (INIS)

Grazer, G.L.

1988-01-01

We have measured the phase difference Δphi between the complex parameters eta 00 and eta/sub +-/, which describe CP violation in the decays of neutral kaons to neutral and charged pion final states. Three phases are observable in the interference effects which come about from a superposition of short- and long-lived kaons. A non-zero value of Δphi, suggested by a 1979 measurement made by a group at New York University, would imply CPT violation. In a recent experiment at Fermilab, we created K/sub L/-K/sub S/ interference by sending a pure K/sub L/ beam though a regenerator, producing a beam which contained a superposition of both K/sub S/ and K/sub L/. We collected over 14,000 decays of these kaons to π 0 π 0 and about 110,000 to π + π - . The shapes of the proper time spectra for these decays depend on the phases of eta 00 for decays to neutral pions and eta/sub +-/ for decays to charged pions. By comparing these spectra with corresponding distributions obtained from a Monte Carlo simulation, we find that the phase difference phi 00 - phi/sub +-/ = - 0.2 0 +- 9.8 0 (statistics) +- 5.8 0 (systematic). We therefore see no evidence for CPT violation, although within the uncetainty our result is compatible with the NYU measurement. 19 refs., 69 figs., 10 tabs

Testing strong factorial invariance using three-level structural equation modeling

Directory of Open Access Journals (Sweden)

Suzanne eJak

2014-07-01

Full Text Available Within structural equation modeling, the most prevalent model to investigate measurement bias is the multigroup model. Equal factor loadings and intercepts across groups in a multigroup model represent strong factorial invariance (absence of measurement bias across groups. Although this approach is possible in principle, it is hardly practical when the number of groups is large or when the group size is relatively small. Jak, Oort and Dolan (2013 showed how strong factorial invariance across large numbers of groups can be tested in a multilevel structural equation modeling framework, by treating group as a random instead of a fixed variable. In the present study, this model is extended for use with three-level data. The proposed method is illustrated with an investigation of strong factorial invariance across 156 school classes and 50 schools in a Dutch dyscalculia test, using three-level structural equation modeling.

Test of Lorentz and CPT violation with short baseline neutrino oscillation excesses

International Nuclear Information System (INIS)

Aguilar-Arevalo, A.A.; Anderson, C.E.; Bazarko, A.O.; Brice, S.J.; Brown, B.C.; Bugel, L.; Cao, J.; Coney, L.; Conrad, J.M.; Cox, D.C.; Curioni, A.; Dharmapalan, R.; Djurcic, Z.; Finley, D.A.; Fleming, B.T.; Ford, R.; Garcia, F.G.; Garvey, G.T.; Grange, J.; Green, C.

2013-01-01

The sidereal time dependence of MiniBooNE ν e and ν ¯ e appearance data is analyzed to search for evidence of Lorentz and CPT violation. An unbinned Kolmogorov–Smirnov (K–S) test shows both the ν e and ν ¯ e appearance data are compatible with the null sidereal variation hypothesis to more than 5%. Using an unbinned likelihood fit with a Lorentz-violating oscillation model derived from the Standard Model Extension (SME) to describe any excess events over background, we find that the ν e appearance data prefer a sidereal time-independent solution, and the ν ¯ e appearance data slightly prefer a sidereal time-dependent solution. Limits of order 10 −20 GeV are placed on combinations of SME coefficients. These limits give the best limits on certain SME coefficients for ν μ →ν e and ν ¯ μ →ν ¯ e oscillations. The fit values and limits of combinations of SME coefficients are provided.

Measurements of CPT Violation at LHCb

CERN Document Server

INSPIRE-00260865

2017-01-01

Recent measurements of CPT violation and Lorentz symmetry breaking in $B^0-\\bar{B}^0$ mixing and $B^0_s-\\bar{B}^0_s$ mixing, obtained from data taken by the LHCb experiment, are highlighted. The results are expressed in terms of the Standard-Model Extension (SME) coefficients, which incorporate both CPT and Lorentz violation. Due to the large boost of the $B$ mesons at LHCb, the SME coefficients can be determined with high precision. The bounds on these coefficients are improved significantly compared to previous measurements.

Probing CPT violation in neutrino oscillation: A three flavor analysis

International Nuclear Information System (INIS)

Samanta, Abhijit

2010-01-01

We have studied CPT violation in neutrino oscillation considering three flavor framework with matter effect. We have constructed a new way to find the oscillation probability incorporating CPT violating terms without any approximation. Then CPT violation with atmospheric neutrinos for a magnetized iron calorimeter detector considering the muons (directly measurable with high resolution) of the charge current events has been studied for zero and nonzero θ 13 values. It is found that a potential bound of δb 32 ≤6x10 -24 GeV at 99% CL can be obtained with 1 Mton.year exposure of this detector; and unlike neutrino beam experiments, there is no possibility to generate 'fake' CPT violation due to matter effect with atmospheric neutrinos. The advantages of atmospheric neutrinos to discriminate CPT violation from CP violation and nonstandard interactions are also discussed.

A Test for Cluster Bias: Detecting Violations of Measurement Invariance across Clusters in Multilevel Data

Science.gov (United States)

Jak, Suzanne; Oort, Frans J.; Dolan, Conor V.

2013-01-01

We present a test for cluster bias, which can be used to detect violations of measurement invariance across clusters in 2-level data. We show how measurement invariance assumptions across clusters imply measurement invariance across levels in a 2-level factor model. Cluster bias is investigated by testing whether the within-level factor loadings…

Metabolomic profiling reveals a role for CPT1c in neuronal oxidative metabolism.

Science.gov (United States)

Lee, Jieun; Wolfgang, Michael J

2012-10-25

Carnitine Palmitoyltransferase-1c (CPT1c) is a neuron specific homologue of the carnitine acyltransferase family of enzymes. CPT1 isoenzymes transfer long chain acyl groups to carnitine. This constitutes a rate setting step for mitochondrial fatty acid beta-oxidation by facilitating the initial step in acyl transfer to the mitochondrial matrix. In general, neurons do not heavily utilize fatty acids for bioenergetic needs and definitive enzymatic activity has been unable to be demonstrated for CPT1c. Although there are studies suggesting an enzymatic role of CPT1c, its role in neurochemistry remains elusive. In order to better understand how CPT1c functions in neural metabolism, we performed unbiased metabolomic profiling on wild-type (WT) and CPT1c knockout (KO) mouse brains. Consistent with the notion that CPT1c is not involved in fatty acid beta-oxidation, there were no changes in metabolites associated with fatty acid oxidation. Endocannabinoids were suppressed in the CPT1c KO, which may explain the suppression of food intake seen in CPT1c KO mice. Although products of beta-oxidation were unchanged, small changes in carnitine and carnitine metabolites were observed. Finally, we observed changes in redox homeostasis including a greater than 2-fold increase in oxidized glutathione. This indicates that CPT1c may play a role in neural oxidative metabolism. Steady-state metabolomic analysis of CPT1c WT and KO mouse brains identified a small number of metabolites that differed between CPT1c WT and KO mice. The subtle changes in a broad range of metabolites in vivo indicate that CPT1c does not play a significant or required role in fatty acid oxidation; however, it could play an alternative role in neuronal oxidative metabolism.

Metabolomic profiling reveals a role for CPT1c in neuronal oxidative metabolism

Directory of Open Access Journals (Sweden)

Lee Jieun

2012-10-01

Full Text Available Abstract Background Carnitine Palmitoyltransferase-1c (CPT1c is a neuron specific homologue of the carnitine acyltransferase family of enzymes. CPT1 isoenzymes transfer long chain acyl groups to carnitine. This constitutes a rate setting step for mitochondrial fatty acid beta-oxidation by facilitating the initial step in acyl transfer to the mitochondrial matrix. In general, neurons do not heavily utilize fatty acids for bioenergetic needs and definitive enzymatic activity has been unable to be demonstrated for CPT1c. Although there are studies suggesting an enzymatic role of CPT1c, its role in neurochemistry remains elusive. Results In order to better understand how CPT1c functions in neural metabolism, we performed unbiased metabolomic profiling on wild-type (WT and CPT1c knockout (KO mouse brains. Consistent with the notion that CPT1c is not involved in fatty acid beta-oxidation, there were no changes in metabolites associated with fatty acid oxidation. Endocannabinoids were suppressed in the CPT1c KO, which may explain the suppression of food intake seen in CPT1c KO mice. Although products of beta-oxidation were unchanged, small changes in carnitine and carnitine metabolites were observed. Finally, we observed changes in redox homeostasis including a greater than 2-fold increase in oxidized glutathione. This indicates that CPT1c may play a role in neural oxidative metabolism. Conclusions Steady-state metabolomic analysis of CPT1c WT and KO mouse brains identified a small number of metabolites that differed between CPT1c WT and KO mice. The subtle changes in a broad range of metabolites in vivo indicate that CPT1c does not play a significant or required role in fatty acid oxidation; however, it could play an alternative role in neuronal oxidative metabolism.

Production and detection of cold anti-hydrogen atoms A first step towards high precision CPT test

CERN Document Server

Variola, A; Bonomi, G; Boutcha, A; Bowe, P; Carraro, C; Cesar, C L; Charlton, M; Doser, Michael; Filippini, V; Fontana, A; Fujiwara, M C; Funakoshi, R; Genova, P; Hangst, J S; Hayano, R S; Jørgensen, L V; Lagomarsino, V; Landua, Rolf; Lindelöf, D; Lodi-Rizzini, E; Macri, M; Madsen, N; Manuzio, G; Montagna, P; Pruys, H S; Regenfus, C; Rotondi, A; Riedler, P; Testera, G; Van der Werf, D P

2003-01-01

Observations of anti-hydrogen in small quantities have been reported at CERN and at FermiLab, but these experiments were not suited to spectroscopy experiments. In 2002 the ATHENA collaboration reported the production and detection of very low energy anti-hydrogen atoms produced in cryogenic environment. This is the first major step in the study of antiatom's internal structure and it can lead to a high precision test of the CPT fundamental symmetry. The method of production and detection of cold anti-hydrogen will be introduced. The absolute rate of anti-hydrogen production and the signal to background ratio in the ATHENA experiment will be discussed. (7 refs) .

The Impact of Partial Measurement Invariance on Testing Moderation for Single and Multi-Level Data.

Science.gov (United States)

Hsiao, Yu-Yu; Lai, Mark H C

2018-01-01

Moderation effect is a commonly used concept in the field of social and behavioral science. Several studies regarding the implication of moderation effects have been done; however, little is known about how partial measurement invariance influences the properties of tests for moderation effects when categorical moderators were used. Additionally, whether the impact is the same across single and multilevel data is still unknown. Hence, the purpose of the present study is twofold: (a) To investigate the performance of the moderation test in single-level studies when measurement invariance does not hold; (b) To examine whether unique features of multilevel data, such as intraclass correlation (ICC) and number of clusters, influence the effect of measurement non-invariance on the performance of tests for moderation. Simulation results indicated that falsely assuming measurement invariance lead to biased estimates, inflated Type I error rates, and more gain or more loss in power (depends on simulation conditions) for the test of moderation effects. Such patterns were more salient as sample size and the number of non-invariant items increase for both single- and multi-level data. With multilevel data, the cluster size seemed to have a larger impact than the number of clusters when falsely assuming measurement invariance in the moderation estimation. ICC was trivially related to the moderation estimates. Overall, when testing moderation effects with categorical moderators, employing a model that accounts for the measurement (non)invariance structure of the predictor and/or the outcome is recommended.

Soil classification based on cone penetration test (CPT) data in Western Central Java

Science.gov (United States)

Apriyono, Arwan; Yanto, Santoso, Purwanto Bekti; Sumiyanto

2018-03-01

This study presents a modified friction ratio range for soil classification i.e. gravel, sand, silt & clay and peat, using CPT data in Western Central Java. The CPT data was obtained solely from Soil Mechanic Laboratory of Jenderal Soedirman University that covers more than 300 sites within the study area. About 197 data were produced from data filtering process. IDW method was employed to interpolated friction ratio values in a regular grid point for soil classification map generation. Soil classification map was generated and presented using QGIS software. In addition, soil classification map with respect to modified friction ratio range was validated using 10% of total measurements. The result shows that silt and clay dominate soil type in the study area, which is in agreement with two popular methods namely Begemann and Vos. However, the modified friction ratio range produces 85% similarity with laboratory measurements whereby Begemann and Vos method yields 70% similarity. In addition, modified friction ratio range can effectively distinguish fine and coarse grains, thus useful for soil classification and subsequently for landslide analysis. Therefore, modified friction ratio range proposed in this study can be used to identify soil type for mountainous tropical region.

Investigation of Dense Sand Properties in Shallow Depth using CPT and DMT

DEFF Research Database (Denmark)

Gaydadzhiew, Dimitar Todorov; Puscasu, Ionut; Vaitkunaite, Evelina

2015-01-01

ABSTRACT: The present paper is an investigation of the soil parameters of the given Aalborg University Sand No. 1 using the Flat Dilatometer Test (DMT) and the Cone Penetration Test (CPT). This clean sand type is considered to be similar to the sands found in the North Sea area. The research...

Test of Lorentz and CPT violation with short baseline neutrino oscillation excesses

Energy Technology Data Exchange (ETDEWEB)

Aguilar-Arevalo, A.A. [Instituto de Ciencias Nucleares, Universidad Nacional Autonoma de Mexico, D.F. 04510 (Mexico); Anderson, C.E. [Yale University, New Haven, CT 06520 (United States); Bazarko, A.O. [Princeton University, Princeton, NJ 08544 (United States); Brice, S.J.; Brown, B.C. [Fermi National Accelerator Laboratory, Batavia, IL 60510 (United States); Bugel, L. [Massachusetts Institute of Technology, Cambridge, MA 02139 (United States); Cao, J. [University of Michigan, Ann Arbor, MI 48109 (United States); Coney, L. [Columbia University, New York, NY 10027 (United States); Conrad, J.M. [Massachusetts Institute of Technology, Cambridge, MA 02139 (United States); Cox, D.C. [Indiana University, Bloomington, IN 47405 (United States); Curioni, A. [Yale University, New Haven, CT 06520 (United States); Dharmapalan, R. [University of Alabama, Tuscaloosa, AL 35487 (United States); Djurcic, Z. [Argonne National Laboratory, Argonne, IL 60439 (United States); Finley, D.A. [Fermi National Accelerator Laboratory, Batavia, IL 60510 (United States); Fleming, B.T. [Yale University, New Haven, CT 06520 (United States); Ford, R.; Garcia, F.G. [Fermi National Accelerator Laboratory, Batavia, IL 60510 (United States); Garvey, G.T. [Los Alamos National Laboratory, Los Alamos, NM 87545 (United States); Grange, J. [University of Florida, Gainesville, FL 32611 (United States); Green, C. [Fermi National Accelerator Laboratory, Batavia, IL 60510 (United States); Los Alamos National Laboratory, Los Alamos, NM 87545 (United States); and others

2013-01-29

The sidereal time dependence of MiniBooNE {nu}{sub e} and {nu}{sup Macron }{sub e} appearance data is analyzed to search for evidence of Lorentz and CPT violation. An unbinned Kolmogorov-Smirnov (K-S) test shows both the {nu}{sub e} and {nu}{sup Macron }{sub e} appearance data are compatible with the null sidereal variation hypothesis to more than 5%. Using an unbinned likelihood fit with a Lorentz-violating oscillation model derived from the Standard Model Extension (SME) to describe any excess events over background, we find that the {nu}{sub e} appearance data prefer a sidereal time-independent solution, and the {nu}{sup Macron }{sub e} appearance data slightly prefer a sidereal time-dependent solution. Limits of order 10{sup -20} GeV are placed on combinations of SME coefficients. These limits give the best limits on certain SME coefficients for {nu}{sub {mu}}{yields}{nu}{sub e} and {nu}{sup Macron }{sub {mu}}{yields}{nu}{sup Macron }{sub e} oscillations. The fit values and limits of combinations of SME coefficients are provided.

A test for ordinal measurement invariance

NARCIS (Netherlands)

Ligtvoet, R.; Millsap, R.E.; Bolt, D.M.; van der Ark, L.A.; Wang, W.-C.

2015-01-01

One problem with the analysis of measurement invariance is the reliance of the analysis on having a parametric model that accurately describes the data. In this paper an ordinal version of the property of measurement invariance is proposed, which relies only on nonparametric restrictions. This

Scale invariant for one-sided multivariate likelihood ratio tests

Directory of Open Access Journals (Sweden)

Samruam Chongcharoen

2010-07-01

Full Text Available Suppose 1 2 , ,..., n X X X is a random sample from Np ( ,V distribution. Consider 0 1 2 : ... 0 p H      and1 : 0 for 1, 2,..., i H   i  p , let 1 0 H  H denote the hypothesis that 1 H holds but 0 H does not, and let ~ 0 H denote thehypothesis that 0 H does not hold. Because the likelihood ratio test (LRT of 0 H versus 1 0 H  H is complicated, severalad hoc tests have been proposed. Tang, Gnecco and Geller (1989 proposed an approximate LRT, Follmann (1996 suggestedrejecting 0 H if the usual test of 0 H versus ~ 0 H rejects 0 H with significance level 2 and a weighted sum of the samplemeans is positive, and Chongcharoen, Singh and Wright (2002 modified Follmann’s test to include information about thecorrelation structure in the sum of the sample means. Chongcharoen and Wright (2007, 2006 give versions of the Tang-Gnecco-Geller tests and Follmann-type tests, respectively, with invariance properties. With LRT’s scale invariant desiredproperty, we investigate its powers by using Monte Carlo techniques and compare them with the tests which we recommendin Chongcharoen and Wright (2007, 2006.

Testing Lorentz invariance of dark matter

CERN Document Server

Blas, Diego; Sibiryakov, Sergey

2012-01-01

We study the possibility to constrain deviations from Lorentz invariance in dark matter (DM) with cosmological observations. Breaking of Lorentz invariance generically introduces new light gravitational degrees of freedom, which we represent through a dynamical timelike vector field. If DM does not obey Lorentz invariance, it couples to this vector field. We find that this coupling affects the inertial mass of small DM halos which no longer satisfy the equivalence principle. For large enough lumps of DM we identify a (chameleon) mechanism that restores the inertial mass to its standard value. As a consequence, the dynamics of gravitational clustering are modified. Two prominent effects are a scale dependent enhancement in the growth of large scale structure and a scale dependent bias between DM and baryon density perturbations. The comparison with the measured linear matter power spectrum in principle allows to bound the departure from Lorentz invariance of DM at the per cent level.

Testing Lorentz invariance of dark matter

Energy Technology Data Exchange (ETDEWEB)

Blas, Diego [Theory Group, Physics Department, CERN, CH-1211 Geneva 23 (Switzerland); Ivanov, Mikhail M.; Sibiryakov, Sergey, E-mail: diego.blas@cern.ch, E-mail: mm.ivanov@physics.msu.ru, E-mail: sibir@inr.ac.ru [Faculty of Physics, Moscow State University, Vorobjevy Gory, 119991 Moscow (Russian Federation)

2012-10-01

We study the possibility to constrain deviations from Lorentz invariance in dark matter (DM) with cosmological observations. Breaking of Lorentz invariance generically introduces new light gravitational degrees of freedom, which we represent through a dynamical timelike vector field. If DM does not obey Lorentz invariance, it couples to this vector field. We find that this coupling affects the inertial mass of small DM halos which no longer satisfy the equivalence principle. For large enough lumps of DM we identify a (chameleon) mechanism that restores the inertial mass to its standard value. As a consequence, the dynamics of gravitational clustering are modified. Two prominent effects are a scale dependent enhancement in the growth of large scale structure and a scale dependent bias between DM and baryon density perturbations. The comparison with the measured linear matter power spectrum in principle allows to bound the departure from Lorentz invariance of DM at the per cent level.

Testing Lorentz invariance in β decay

Directory of Open Access Journals (Sweden)

Sytema A.

2014-03-01

Experimentally we exploit the Gamow-Teller transition of polarized 20Na, where we can test the dependence of the β-decay rate on the spin orientation of 20Na. The polarization degree is measured using the β asymmetry, while the decay rate is measured by the γ yield. A change in the γ rate, when reversing the spin, implies Lorentz invariance violation. The decay rate should depend on sidereal time and the polarization direction relative to the rotation axis of the earth. The method of the measurement will be presented, together with the first results.

Use of the Cone Penetration Testing (CPT) method to interpret late Quaternary tide-dominated successions: A case study from the eastern China coastal plain

Science.gov (United States)

Zhang, Xia; Lin, Chun-Ming; Dalrymple, Robert W.; Gao, Shu; Canas, Daniel T.

2018-06-01

We evaluate the applicability of cone penetration testing (CPT), calibrated using adjacent cores, as a tool for the sedimentological and stratigraphic examination of late Quaternary tide-dominated successions in the eastern China coastal plain. The results indicate that the sedimentary facies and sequence-stratigraphic surfaces can be readily distinguished using CPT profiles in the Qiantang River incised-valley system because of their distinctive mechanical behavior. The lithologic character of the various facies, which is controlled mainly by sediment supply, dynamic processes and post-depositional diagenesis, is the key factor affecting how well the CPT technique works. Within this particular macrotidal environment, which is dominated by non-cohesive sand and silt in the tidal channels, the accumulation of fluid mud is rare. Consequently, the tidal-channel deposits exhibit the geotechnical properties of coarse-grained sediments, and can be easily distinguished from the mud-dominated facies. However, in the nearby Changjiang delta system which is characterized by very high suspended-sediment concentrations and an abundance of fine-grained cohesive sediments, the presence of channel-bottom fluid muds makes it difficult to recognize channel deposits, because of the lack of a sharp lithologic contrast at their base. Consequently, the CPT method might not be as universally effective in tide-dominated systems as it appears to be in wave-dominated settings. Care is needed in the interpretation of the results from tide-dominated successions because of the widespread presence of fluid muds, the heterolithic nature of tidal deposits, the rheological similarity between adjacent facies, and the averaging of geotechnical properties between the alternating finer and coarser layers.

Irinotecan (CPT-11)-induced elevation of bile acids potentiates suppression of IL-10 expression

International Nuclear Information System (INIS)

Fang, Zhong-Ze; Zhang, Dunfang; Cao, Yun-Feng; Xie, Cen; Lu, Dan; Sun, Dong-Xue; Tanaka, Naoki; Jiang, Changtao; Chen, Qianming; Chen, Yu; Wang, Haina; Gonzalez, Frank J.

2016-01-01

Irinotecan (CPT-11) is a first-line anti-colon cancer drug, however; CPT-11-induced toxicity remains a key factor limiting its clinical application. To search for clues to the mechanism of CPT-11-induced toxicity, metabolomics was applied using ultra-performance liquid chromatography coupled with electrospray ionization quadrupole time-of-flight mass spectrometry. Intraperitoneal injection of 50 mg/kg of CPT-11 induced loss of body weight, and intestine toxicity. Changes in gallbladder morphology suggested alterations in bile acid metabolism, as revealed at the molecular level by analysis of the liver, bile, and ileum metabolomes between the vehicle-treated control group and the CPT-11-treated group. Analysis of immune cell populations further showed that CPT-11 treatment significantly decreased the IL-10-producing CD4 T cell frequency in intestinal lamina propria lymphocytes, but not in spleen or mesenteric lymph nodes. In vitro cell culture studies showed that the addition of bile acids deoxycholic acid and taurodeoxycholic acid accelerated the CPT-11-induced suppression of IL-10 secretion by activated CD4 + naive T cells isolated from mouse splenocytes. These results showed that CPT-11 treatment caused metabolic changes in the composition of bile acids that altered CPT-11-induced suppression of IL-10 expression. - Highlights: • CPT-11 is an effective anticancer drug, but induced toxicity limits its application in the clinic. • CPT-11 decreased IL-10-producing CD4 T cell frequency in intestinal lamina propria lymphocytes. • CPT-11 altered the composition of bile acid metabolites, notably DCA and TDCA in liver, bile and intestine. • DCA and TDCA potentiated CPT-11-induced suppression of IL-10 secretion by active CD4 + naive T cells.

Irinotecan (CPT-11)-induced elevation of bile acids potentiates suppression of IL-10 expression

Energy Technology Data Exchange (ETDEWEB)

Fang, Zhong-Ze [Laboratory of Metabolism, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD (United States); Department of Toxicology, School of Public Health, Tianjin Medical University, Tianjin (China); Joint Center for Translational Medicine, Dalian Institute of Chemical Physics, Chinese Academy of Sciences and First Affiliated Hospital of Liaoning Medical University, Dalian (China); Zhang, Dunfang [State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu (China); Cao, Yun-Feng [Joint Center for Translational Medicine, Dalian Institute of Chemical Physics, Chinese Academy of Sciences and First Affiliated Hospital of Liaoning Medical University, Dalian (China); Xie, Cen [Laboratory of Metabolism, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD (United States); Lu, Dan [Department of Immunology, Tianjin Key Laboratory of Cellular and Molecular Immunology, Tianjin Medical University, Tianjin (China); Sun, Dong-Xue; Tanaka, Naoki; Jiang, Changtao [Laboratory of Metabolism, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD (United States); Chen, Qianming; Chen, Yu [State Key Laboratory of Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu (China); Wang, Haina [School of Pharmaceutical Sciences, Shandong University, Jinan (China); Gonzalez, Frank J., E-mail: gonzalef@mail.nih.gov [Laboratory of Metabolism, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD (United States)

2016-01-15

Irinotecan (CPT-11) is a first-line anti-colon cancer drug, however; CPT-11-induced toxicity remains a key factor limiting its clinical application. To search for clues to the mechanism of CPT-11-induced toxicity, metabolomics was applied using ultra-performance liquid chromatography coupled with electrospray ionization quadrupole time-of-flight mass spectrometry. Intraperitoneal injection of 50 mg/kg of CPT-11 induced loss of body weight, and intestine toxicity. Changes in gallbladder morphology suggested alterations in bile acid metabolism, as revealed at the molecular level by analysis of the liver, bile, and ileum metabolomes between the vehicle-treated control group and the CPT-11-treated group. Analysis of immune cell populations further showed that CPT-11 treatment significantly decreased the IL-10-producing CD4 T cell frequency in intestinal lamina propria lymphocytes, but not in spleen or mesenteric lymph nodes. In vitro cell culture studies showed that the addition of bile acids deoxycholic acid and taurodeoxycholic acid accelerated the CPT-11-induced suppression of IL-10 secretion by activated CD4{sup +} naive T cells isolated from mouse splenocytes. These results showed that CPT-11 treatment caused metabolic changes in the composition of bile acids that altered CPT-11-induced suppression of IL-10 expression. - Highlights: • CPT-11 is an effective anticancer drug, but induced toxicity limits its application in the clinic. • CPT-11 decreased IL-10-producing CD4 T cell frequency in intestinal lamina propria lymphocytes. • CPT-11 altered the composition of bile acid metabolites, notably DCA and TDCA in liver, bile and intestine. • DCA and TDCA potentiated CPT-11-induced suppression of IL-10 secretion by active CD4{sup +} naive T cells.

CPT-11 activates NLRP3 inflammasome through JNK and NF-κB signalings

Energy Technology Data Exchange (ETDEWEB)

Li, Qian [Department of Oncology, The First Affiliated Hospital with Nanjing Medical University, 300, Guangzhou Road, Nanjing 210029 (China); Zhang, Xiong [State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, 163 Xianlin Avenue, Nanjing 210046 (China); Wang, Weicheng; Li, LeLe [Department of Oncology, The First Affiliated Hospital with Nanjing Medical University, 300, Guangzhou Road, Nanjing 210029 (China); Xu, Qiang, E-mail: molpharm@163.com [State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, 163 Xianlin Avenue, Nanjing 210046 (China); Wu, Xudong, E-mail: xudongwu@nju.edu.cn [State Key Laboratory of Pharmaceutical Biotechnology, School of Life Sciences, Nanjing University, 163 Xianlin Avenue, Nanjing 210046 (China); Gu, Yanhong, E-mail: guluer@163.com [Department of Oncology, The First Affiliated Hospital with Nanjing Medical University, 300, Guangzhou Road, Nanjing 210029 (China)

2015-12-01

CPT-11 is widely used for cancer therapy as a chemotherapeutic agent. Despite its good efficacy, a large number of side effects appeared during decades of clinical application. Delayed diarrhea, at dose limiting toxicity, happens after 24 h of treatment and the rate of occurrence is up to 90%. Although many investments have been made on this negative impact, the real molecular mechanism of delayed diarrhea is poorly understood. In this study, we have discovered that CPT-11 promotes macrophage infiltration into intestinal tissues and activates the NOD-like receptor family, pyrin domain containing 3 (NLRP3) inflammasome, resulting in a robust IL-1β response and colonic inflammation similar to DSS (dextran sodium sulfate) induced experimental colitis. CPT-11 plus LPS primed mouse bone marrow-derived macrophages (BMDMs) and human acute monocytic leukemia cells (THP-1 cells) staying in a highly activated status, showing increased caspase-1 activity and releasing great amounts of IL-1β and IL-18 as detected by ELISA and western blot. A further mechanism showed that JNK and NF-κB signaling pathways participated in inflammatory responses activated by CPT-11. These results prompted us to suggest that the NLRP3-IL-1β signaling pathway might play an important role in CPT11-induced colitis. Our findings provide a basis for developing novel strategies that improve clinical implications of CPT-11. - Highlights: • CPT-11 induced experimental colitis in vivo. • CPT-11 induced intestine injury and macrophage infiltration. • CPT-11 significantly elevated levels of macrophage derived inflammatory cytokines in mice intestines. • CPT-11 activated NLRP3 inflammasome in vitro and in vivo. • CPT-11 activated JNK and NF-κB signalings in THP-1 and BMDMs.

Combining CPT-conjugate neutrino channels at Fermilab

International Nuclear Information System (INIS)

Jansson, Andreas; Parke, Stephen; Saoulidou, Niki; Mena, Olga

2008-01-01

We explore an alternative strategy to determine the neutrino mass hierarchy by making use of possible future neutrino facilities at Fermilab. Here, we use CPT-conjugate neutrino channels, exploiting a ν μ beam from the NuMI beamline and a ν e beam from a beta-beam experimental setup. Both experiments are performed at approximately the same /L. We present different possible accelerator scenarios for the beta-beam neutrino setup and fluxes. This CPT-conjugate neutrino channel scenario can extract the neutrino mass hierarchy down to sin 2 2θ 13 ≅0.02.

The Impact of Partial Measurement Invariance on Testing Moderation for Single and Multi-Level Data

Directory of Open Access Journals (Sweden)

Yu-Yu Hsiao

2018-05-01

Full Text Available Moderation effect is a commonly used concept in the field of social and behavioral science. Several studies regarding the implication of moderation effects have been done; however, little is known about how partial measurement invariance influences the properties of tests for moderation effects when categorical moderators were used. Additionally, whether the impact is the same across single and multilevel data is still unknown. Hence, the purpose of the present study is twofold: (a To investigate the performance of the moderation test in single-level studies when measurement invariance does not hold; (b To examine whether unique features of multilevel data, such as intraclass correlation (ICC and number of clusters, influence the effect of measurement non-invariance on the performance of tests for moderation. Simulation results indicated that falsely assuming measurement invariance lead to biased estimates, inflated Type I error rates, and more gain or more loss in power (depends on simulation conditions for the test of moderation effects. Such patterns were more salient as sample size and the number of non-invariant items increase for both single- and multi-level data. With multilevel data, the cluster size seemed to have a larger impact than the number of clusters when falsely assuming measurement invariance in the moderation estimation. ICC was trivially related to the moderation estimates. Overall, when testing moderation effects with categorical moderators, employing a model that accounts for the measurement (noninvariance structure of the predictor and/or the outcome is recommended.

An Affine Invariant Bivariate Version of the Sign Test.

Science.gov (United States)

1987-06-01

words: affine invariance, bivariate quantile, bivariate symmetry, model,. generalized median, influence function , permutation test, normal efficiency...calculate a bivariate version of the influence function , and the resulting form is bounded, as is the case for the univartate sign test, and shows the...terms of a blvariate analogue of IHmpel’s (1974) influence function . The latter, though usually defined as a von-Mises derivative of certain

The Formalization of Fairness: Issues in Testing for Measurement Invariance Using Subtest Scores

Science.gov (United States)

Molenaar, Dylan; Borsboom, Denny

2013-01-01

Measurement invariance is an important prerequisite for the adequate comparison of group differences in test scores. In psychology, measurement invariance is typically investigated by means of linear factor analyses of subtest scores. These subtest scores typically result from summing the item scores. In this paper, we discuss 4 possible problems…

High-precision comparison of the antiproton-to-proton charge-to-mass ratio.

Science.gov (United States)

Ulmer, S; Smorra, C; Mooser, A; Franke, K; Nagahama, H; Schneider, G; Higuchi, T; Van Gorp, S; Blaum, K; Matsuda, Y; Quint, W; Walz, J; Yamazaki, Y

2015-08-13

Invariance under the charge, parity, time-reversal (CPT) transformation is one of the fundamental symmetries of the standard model of particle physics. This CPT invariance implies that the fundamental properties of antiparticles and their matter-conjugates are identical, apart from signs. There is a deep link between CPT invariance and Lorentz symmetry--that is, the laws of nature seem to be invariant under the symmetry transformation of spacetime--although it is model dependent. A number of high-precision CPT and Lorentz invariance tests--using a co-magnetometer, a torsion pendulum and a maser, among others--have been performed, but only a few direct high-precision CPT tests that compare the fundamental properties of matter and antimatter are available. Here we report high-precision cyclotron frequency comparisons of a single antiproton and a negatively charged hydrogen ion (H(-)) carried out in a Penning trap system. From 13,000 frequency measurements we compare the charge-to-mass ratio for the antiproton (q/m)p- to that for the proton (q/m)p and obtain (q/m)p-/(q/m)p − 1 =1(69) × 10(-12). The measurements were performed at cyclotron frequencies of 29.6 megahertz, so our result shows that the CPT theorem holds at the atto-electronvolt scale. Our precision of 69 parts per trillion exceeds the energy resolution of previous antiproton-to-proton mass comparisons as well as the respective figure of merit of the standard model extension by a factor of four. In addition, we give a limit on sidereal variations in the measured ratio of baryonic antimatter, and it sets a new limit on the gravitational anomaly parameter of |α − 1| < 8.7 × 10(-7).

Kampo medicine "Dai-kenchu-to" prevents CPT-11-induced small-intestinal injury in rats.

Science.gov (United States)

Chikakiyo, Motoya; Shimada, Mitsuo; Nakao, Toshihiro; Higashijima, Jun; Yoshikawa, Kozo; Nishioka, Masanori; Iwata, Takashi; Kurita, Nobuhiro

2012-01-01

The key anticancer agent, CPT-11 (irinotecan hydrochloride), induces severe diarrhea clinically. We investigated the effect of a Kampo medicine, Dai-kenchu-to (DKT), on CPT-11-induced intestinal injuries in rats. Twenty-four male Wistar rats were divided into three groups: a control group; a CPT-11 group, given CPT-11 150 mg/kg intraperitoneally for 2 days; and a DKT group, given DKT 300 mg/kg orally for 5 days with CPT-11 150 mg/kg intraperitoneally on days 4 and 5. The rats were killed on day 6. Interleukin (IL)-1β, IL-12, interferon (IFN)-γ, and tumor necrosis factor-α expression in the small intestine of the CPT-11 group was significantly higher than that of the control group. Interleukin-1β and IFN-γ expression was improved significantly by DKT (P DKT (P DKT suppressed CPT-11 induced inflammatory cytokines and apoptosis in the intestinal mucosa and maintained the mucosal integrity.

Power properties of invariant tests for spatial autocorrelation in linear regression

NARCIS (Netherlands)

Martellosio, F.

2006-01-01

Many popular tests for residual spatial autocorrelation in the context of the linear regression model belong to the class of invariant tests. This paper derives a number of exact properties of the power function of such tests. In particular, we extend the work of Krämer (2005, Journal of Statistical

Radiative generation of the CPT-even gauge term of the SME from a dimension-five nonminimal coupling term

Energy Technology Data Exchange (ETDEWEB)

Casana, R., E-mail: rodolfo.casana@gmail.com [Universidade Federal do Maranhão (UFMA), Departamento de Física, Campus Universitário do Bacanga, São Luís, MA, 65085-580 (Brazil); Ferreira, M.M., E-mail: manojr07@ibest.com.br [Universidade Federal do Maranhão (UFMA), Departamento de Física, Campus Universitário do Bacanga, São Luís, MA, 65085-580 (Brazil); Maluf, R.V., E-mail: robertovinhaes@fisica.ufc.br [Universidade Federal do Ceará (UFC), Departamento de Física, Campus do Pici, Fortaleza, CE, C.P. 6030, 60455-760 (Brazil); Santos, F.E.P. dos, E-mail: fredegol@ibest.com.br [Universidade Federal do Maranhão (UFMA), Departamento de Física, Campus Universitário do Bacanga, São Luís, MA, 65085-580 (Brazil)

2013-11-04

In this Letter we show for the first time that the usual CPT-even gauge term of the Standard Model Extension (SME), in its full structure, can be radiatively generated, in a gauge invariant level, in the context of a modified QED endowed with a dimension-five nonminimal coupling term recently proposed in the literature. As a consequence, the existing upper bounds on the coefficients of the tensor (K{sub F}) can be used to improve the bounds on the magnitude of the nonminimal coupling, λ(K{sub σF}), by the factors 10{sup 5} or 10{sup 25}. The nonminimal coupling also generates higher-order derivative contributions to the gauge field effective action quadratic terms.

Anomalous Lorentz and CPT violation from a local Chern-Simons-like term in the effective gauge-field action

Science.gov (United States)

Ghosh, K. J. B.; Klinkhamer, F. R.

2018-01-01

We consider four-dimensional chiral gauge theories defined over a spacetime manifold with topology R3 ×S1 and periodic boundary conditions over the compact dimension. The effective gauge-field action is calculated for Abelian U (1) gauge fields Aμ (x) which depend on all four spacetime coordinates (including the coordinate x4 ∈S1 of the compact dimension) and have vanishing components A4 (x) (implying trivial holonomies in the 4-direction). Our calculation shows that the effective gauge-field action contains a local Chern-Simons-like term which violates Lorentz and CPT invariance. This result is established perturbatively with a generalized Pauli-Villars regularization and nonperturbatively with a lattice regularization based on Ginsparg-Wilson fermions.

Testing Measurement Invariance Using MIMIC: Likelihood Ratio Test with a Critical Value Adjustment

Science.gov (United States)

Kim, Eun Sook; Yoon, Myeongsun; Lee, Taehun

2012-01-01

Multiple-indicators multiple-causes (MIMIC) modeling is often used to test a latent group mean difference while assuming the equivalence of factor loadings and intercepts over groups. However, this study demonstrated that MIMIC was insensitive to the presence of factor loading noninvariance, which implies that factor loading invariance should be…

Model-based classification of CPT data and automated lithostratigraphic mapping for high-resolution characterization of a heterogeneous sedimentary aquifer

OpenAIRE

Rogiers, Bart; Mallants, Dirk; Batelaan, Okke; Gedeon, Matej; Huysmans, Marijke; Dassargues, Alain

2017-01-01

Cone penetration testing (CPT) is one of the most efficient and versatile methods currently available for geotechnical, lithostratigraphic and hydrogeological site characterization. Currently available methods for soil behaviour type classification (SBT) of CPT data however have severe limitations, often restricting their application to a local scale. For parameterization of regional groundwater flow or geotechnical models, and delineation of regional hydro- or lithostratigraphy, regional SBT...

Production and detection of cold antihydrogen atoms

CERN Multimedia

Amoretti, M; Bonomi, G; Bouchta, A; Bowe, P; Carraro, C; Cesar, C L; Charlton, M; Collier, M; Doser, Michael; Filippini, V; Fine, K S; Fontana, A; Fujiwara, M C; Funakoshi, R; Genova, P; Hangst, J S; Hayano, R S; Holzscheiter, M H; Jørgensen, L V; Lagomarsino, V; Landua, Rolf; Landua, Rolf; Lindelöf, D; Lodi-Rizzini, E; Macri, M; Madsen, N; Manuzio, G; Marchesotti, M; Montagna, P; Pruys, H S; Regenfus, C; Riedler, P; Rochet, J; Rotondi, A; Rouleau, G; Testera, G; Van der Werf, D P; Variola, A; Watson, T L; CERN. Geneva

2002-01-01

A theoretical underpinning of the standard model of fundamental particles and interactions is CPT invariance, which requires that the laws of physics be invariant under the combined discrete operations of charge conjugation, parity and time reversal. Antimatter, the existence of which was predicted by Dirac, can be used to test the CPT theorem experimental investigations involving comparisons of particles with antiparticles are numerous. Cold atoms and anti-atoms, such as hydrogen and anti-hydrogen, could form the basis of a new precise test, as CPT invariance implies that they must have the same spectrum. Observations of antihydrogen in small quantities and at high energies have been reported at the European Organization for Nuclear Research (CERN) and at Fermilab, but were not suited to precision comparison measurements. Here we demonstrate the production of antihydrogen atoms at very low energy by mixing trapped antiprotons and positrons in a cryogenic environment. The neutral anti-atoms have been detected...

Liquefaction assessment based on combined use of CPT and shear wave velocity measurements

Science.gov (United States)

Bán, Zoltán; Mahler, András; Győri, Erzsébet

2017-04-01

Soil liquefaction is one of the most devastating secondary effects of earthquakes and can cause significant damage in built infrastructure. For this reason liquefaction hazard shall be considered in all regions where moderate-to-high seismic activity encounters with saturated, loose, granular soil deposits. Several approaches exist to take into account this hazard, from which the in-situ test based empirical methods are the most commonly used in practice. These methods are generally based on the results of CPT, SPT or shear wave velocity measurements. In more complex or high risk projects CPT and VS measurement are often performed at the same location commonly in the form of seismic CPT. Furthermore, VS profile determined by surface wave methods can also supplement the standard CPT measurement. However, combined use of both in-situ indices in one single empirical method is limited. For this reason, the goal of this research was to develop such an empirical method within the framework of simplified empirical procedures where the results of CPT and VS measurements are used in parallel and can supplement each other. The combination of two in-situ indices, a small strain property measurement with a large strain measurement, can reduce uncertainty of empirical methods. In the first step by careful reviewing of the already existing liquefaction case history databases, sites were selected where the records of both CPT and VS measurement are available. After implementing the necessary corrections on the gathered 98 case histories with respect to fines content, overburden pressure and magnitude, a logistic regression was performed to obtain the probability contours of liquefaction occurrence. Logistic regression is often used to explore the relationship between a binary response and a set of explanatory variables. The occurrence or absence of liquefaction can be considered as binary outcome and the equivalent clean sand value of normalized overburden corrected cone tip

CPLEAR experiment at CERN: Measurement of CP, T and CPT in the neutral kaon system

International Nuclear Information System (INIS)

Adler, R.; Backenstoss, G.; Eckart, B.; Felder, C.; Leimgruber, F.; Pavlopoulos, P.; Polivka, G.; Rickenbach, R.; Santoni, C.; Schietinger, T.; Tauscher, L.; Vlachos, S.; Angelopoulos, A.; Apostolakis, A.; Sakeliou, L.; Aslanides, E.; Bertin, V.; Ealet, A.; Fassnacht, P.; Henry-Couannier, F.

1997-01-01

Using strangeness tagging at production time, CPLEAR measures K 0 /K-bar 0 time-dependent asymmetries in pionic and semileptonic kaon decays. From those, a set of parameters describing CP, T and CPT violation in neutral kaon mixing and decay can be determined. Strangeness tagging at decay time with the lepton charge allows for time-reversal violation to be directly observed with a significance of more than three standard deviations. The precision on each of the CPT violation parameters is discussed. The mass equality of the K 0 and K-bar 0 is tested within 4.x10 -19 GeV

CPT1α over-expression increases long-chain fatty acid oxidation and reduces cell viability with incremental palmitic acid concentration in 293T cells

International Nuclear Information System (INIS)

Jambor de Sousa, Ulrike L.; Koss, Michael D.; Fillies, Marion; Gahl, Anja; Scheeder, Martin R.L.; Cardoso, M. Cristina; Leonhardt, Heinrich; Geary, Nori; Langhans, Wolfgang; Leonhardt, Monika

2005-01-01

To test the cellular response to an increased fatty acid oxidation, we generated a vector for an inducible expression of the rate-limiting enzyme carnitine palmitoyl-transferase 1α (CPT1α). Human embryonic 293T kidney cells were transiently transfected and expression of the CPT1α transgene in the tet-on vector was activated with doxycycline. Fatty acid oxidation was measured by determining the conversion of supplemented, synthetic cis-10-heptadecenoic acid (C17:1n-7) to C15:ln-7. CPT1α over-expression increased mitochondrial long-chain fatty acid oxidation about 6-fold. Addition of palmitic acid (PA) decreased viability of CPT1α over-expressing cells in a concentration-dependent manner. Both, PA and CPT1α over-expression increased cell death. Interestingly, PA reduced total cell number only in cells over-expressing CPT1α, suggesting an effect on cell proliferation that requires PA translocation across the mitochondrial inner membrane. This inducible expression system should be well suited to study the roles of CPT1 and fatty acid oxidation in lipotoxicity and metabolism in vivo

Tests of Lorentz invariance using a microwave resonator

International Nuclear Information System (INIS)

Wolf, Peter; Bize, Sebastien; Clairon, Andre; Santarelli, Giorgio; Luiten, Andre N.; Tobar, Michael E.

2003-01-01

The frequencies of a cryogenic sapphire oscillator and a hydrogen maser are compared to set new constraints on a possible violation of Lorentz invariance. We determine the variation of the oscillator frequency as a function of its orientation (Michelson-Morley test) and of its velocity (Kennedy-Thorndike test) with respect to a preferred frame candidate. We constrain the corresponding parameters of the Mansouri and Sexl test theory to δ-β+1/2=(1.5±4.2)x10 -9 and β-α-1=(-3.1±6.9)x10 -7 which is of the same order as the best previous result for the former and represents a 30-fold improvement for the latter

A more general model for testing measurement invariance and differential item functioning.

Science.gov (United States)

Bauer, Daniel J

2017-09-01

The evaluation of measurement invariance is an important step in establishing the validity and comparability of measurements across individuals. Most commonly, measurement invariance has been examined using 1 of 2 primary latent variable modeling approaches: the multiple groups model or the multiple-indicator multiple-cause (MIMIC) model. Both approaches offer opportunities to detect differential item functioning within multi-item scales, and thereby to test measurement invariance, but both approaches also have significant limitations. The multiple groups model allows 1 to examine the invariance of all model parameters but only across levels of a single categorical individual difference variable (e.g., ethnicity). In contrast, the MIMIC model permits both categorical and continuous individual difference variables (e.g., sex and age) but permits only a subset of the model parameters to vary as a function of these characteristics. The current article argues that moderated nonlinear factor analysis (MNLFA) constitutes an alternative, more flexible model for evaluating measurement invariance and differential item functioning. We show that the MNLFA subsumes and combines the strengths of the multiple group and MIMIC models, allowing for a full and simultaneous assessment of measurement invariance and differential item functioning across multiple categorical and/or continuous individual difference variables. The relationships between the MNLFA model and the multiple groups and MIMIC models are shown mathematically and via an empirical demonstration. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

TOMOGRAPHIC SITE CHARACTERIZATION USING CPT, ERT, AND GPR

Energy Technology Data Exchange (ETDEWEB)

Rexford M. Morey; Susanne M. Conklin; Stephen P. Farrington, P.E.; James D. Shinn II, P.E.

1999-07-01

The US Department of Energy (DOE) is responsible for the cleanup of inactive DOE sites and for bringing DOE sites and facilities into compliance with federal, state, and local laws and regulations. The DOE's Office of Environmental Management (EM) needs advanced technologies that can make environmental restoration and waste management operations more efficient and less costly. These techniques are required to better characterize the physical, hydrogeological, and chemical properties of the subsurface while minimizing and optimizing the use of boreholes and monitoring wells. Today the cone penetrometer technique (CPT) is demonstrating the value of a minimally invasive deployment system for site characterization. Applied Research Associates, Inc. is developing two new sensor packages for site characterization and monitoring. The two new methods are: (1) Electrical Resistivity Tomography (ERT); and (2) Ground Penetrating Radar (GPR) Tomography. These sensor systems are now integrated with the CPT. The results of this program now make it possible to install ERT and GPR units by CPT methods and thereby reduce installation costs and total costs for ERT and GPR surveys. These two techniques can complement each other in regions of low resistivity where ERT is more effective and regions of high resistivity where GPR is more effective. The results show that CPT-installed GeoWells can be used for both ERT and GPR borehole tomographic subsurface imaging. These two imaging techniques can be used for environmental site characterization and monitoring have numerous and diverse applications within site cleanup and waste management operations.

Anomalous Lorentz and CPT violation from a local Chern–Simons-like term in the effective gauge-field action

Directory of Open Access Journals (Sweden)

K.J.B. Ghosh

2018-01-01

Full Text Available We consider four-dimensional chiral gauge theories defined over a spacetime manifold with topology R3×S1 and periodic boundary conditions over the compact dimension. The effective gauge-field action is calculated for Abelian U(1 gauge fields Aμ(x which depend on all four spacetime coordinates (including the coordinate x4∈S1 of the compact dimension and have vanishing components A4(x (implying trivial holonomies in the 4-direction. Our calculation shows that the effective gauge-field action contains a local Chern–Simons-like term which violates Lorentz and CPT invariance. This result is established perturbatively with a generalized Pauli–Villars regularization and nonperturbatively with a lattice regularization based on Ginsparg–Wilson fermions.

CPT analysis with top physics

Energy Technology Data Exchange (ETDEWEB)

Cembranos, Jose A. R., E-mail: cembra@fis.ucm.es [Universidad Complutense de Madrid, Departamento de Fisica Teorica I (Spain)

2013-03-15

We discuss the possibility of observing CPT violation from top anti-top production in hadronic colliders. We study a general approach by analyzing constraints on the mass difference between the top and anti-top quarks. We present current bounds from Tevatron data, and comment on the prospects for improving these bounds at the LHC and the ILC.

Mutation and biochemical analysis in carnitine palmitoyltransferase type II (CPT II) deficiency

DEFF Research Database (Denmark)

Olpin, S E; Afifi, A; Clark, S

2003-01-01

Carnitine palmitoyltransferase type II (CPT II) deficiency has three basic phenotypes, late-onset muscular (mild), infantile/juvenile hepatic (intermediate) and severe neonatal. We have measured fatty acid oxidation and CPT II activity and performed mutation studies in 24 symptomatic patients...

Breaking diffeomorphism invariance and tests for the emergence of gravity

International Nuclear Information System (INIS)

Anber, Mohamed M.; Aydemir, Ufuk; Donoghue, John F.

2010-01-01

If general relativity is an emergent phenomenon, there may be small violations of diffeomorphism invariance. We propose a phenomenology of perturbatively small violations of general relativity by the inclusion of terms which break general covariance. These can be tested by matching to the parameterized post-Newtonian formalism. The most sensitive tests involve pulsar timing and provide an extremely strong bound, with a dimensionless constraint of order 10 -20 relative to gravitational strength.

Case Study of CPT-based Design Methods for Axial Capacity of Driven Piles in Sand

DEFF Research Database (Denmark)

Thomassen, Kristina; Ibsen, Lars Bo; Andersen, Lars Vabbersgaard

2012-01-01

loaded offshore driven piles in cohesionless soil has until now been the β-method given in API. The API-method is based on the effective overburden pressure at the depth in question. Previous studies show deviations between full-scale load test measurements of the axial pile capacity and the predictions...... found by means of the API-method. Compared to the test measurements, the API-method under-estimates the capacity of short piles (piles in loose sand, and gives a shaft capacity less conservative for piles in tension than for piles in compression......Today the design of onshore axially loaded driven piles in cohesionless soil is commonly made on basis of CPT-based methods because field investigations have shown strong correlation between the local shaft friction and the CPT cone resistance. However, the recommended design method for axially...

Factor structure and invariance test of the alcohol use disorder identification test (AUDIT): Comparison and further validation in a U.S. and Philippines college student sample.

Science.gov (United States)

Tuliao, Antover P; Landoy, Bernice Vania N; McChargue, Dennis E

2016-01-01

The Alcohol Use Disorder Identification Test's factor structure varies depending on population and culture. Because of this inconsistency, this article examined the factor structure of the test and conducted a factorial invariance test between a U.S. and a Philippines college sample. Confirmatory factor analyses indicated that a three-factor solution outperforms the one- and two-factor solution in both samples. Factorial invariance analyses further supports the confirmatory findings by showing that factor loadings were generally invariant across groups; however, item intercepts show non-invariance. Country differences between factors show that Filipino consumption factor mean scores were significantly lower than their U.S. counterparts.

Neutral meson tests of time-reversal symmetry invariance

OpenAIRE

Bevan, Adrian; Inguglia, Gianluca; Zoccali, Michele

2013-01-01

The laws of quantum physics can be studied under the mathematical operation T that inverts the direction of time. Strong and electromagnetic forces are known to be invariant under temporal inversion, however the weak force is not. The BaBar experiment recently exploited the quantum-correlated production of pairs of B0 mesons to show that T is a broken symmetry. Here we show that it is possible to perform a wide range of tests of quark flavour changing processes under T in order to validate th...

Lorentz and CPT violation in QED revisited: A missing analysis

Energy Technology Data Exchange (ETDEWEB)

Del Cima, Oswaldo M., E-mail: wadodelcima@if.uff.b [Universidade Federal Fluminense (UFF), Polo Universitario de Rio das Ostras, Rua Recife s/n, 28890-000, Rio das Ostras, RJ (Brazil); Fonseca, Jakson M., E-mail: jakson.fonseca@ufv.b [Universidade Federal de Vicosa (UFV), Departamento de Fisica, Avenida Peter Henry Rolfs s/n, 36570-000, Vicosa, MG (Brazil); Franco, Daniel H.T., E-mail: daniel.franco@ufv.b [Universidade Federal de Vicosa (UFV), Departamento de Fisica, Avenida Peter Henry Rolfs s/n, 36570-000, Vicosa, MG (Brazil); Piguet, Olivier, E-mail: opiguet@pq.cnpq.b [Universidade Federal do Espirito Santo (UFES), Departamento de Fisica, Campus Universitario de Goiabeiras, 29060-900, Vitoria, ES (Brazil)

2010-05-03

We investigate the breakdown of Lorentz symmetry in QED by a CPT violating interaction term consisting of the coupling of an axial fermion current with a constant vector field b, in the framework of algebraic renormalization - a regularization-independent method. We show, to all orders in perturbation theory, that a CPT-odd and Lorentz violating Chern-Simons-like term, definitively, is not radiatively induced by the axial coupling of the fermions with the constant vector b.

Lorentz and CPT violation in QED revisited: A missing analysis

International Nuclear Information System (INIS)

Del Cima, Oswaldo M.; Fonseca, Jakson M.; Franco, Daniel H.T.; Piguet, Olivier

2010-01-01

We investigate the breakdown of Lorentz symmetry in QED by a CPT violating interaction term consisting of the coupling of an axial fermion current with a constant vector field b, in the framework of algebraic renormalization - a regularization-independent method. We show, to all orders in perturbation theory, that a CPT-odd and Lorentz violating Chern-Simons-like term, definitively, is not radiatively induced by the axial coupling of the fermions with the constant vector b.

Test of feasibility of a novel high precision test of time reversal invariance

International Nuclear Information System (INIS)

Samuel, Deepak

2007-01-01

The first results of a feasibility test of a novel high precision test of time reversal invariance are reported. The Time Reversal Invariance test at COSY (TRIC) was planned to measure the time reversal violating observable A y,xz with an accuracy of 10 -6 in proton-deuteron (p-d) scattering. A novel technique for measuring total cross sections is introduced and the achievable precision of this measuring technique is tested. The correlation coefficient A y,y in p-d scattering fakes a time-reversal violating effect. This work reports the feasibility test of the novel method in the measurement of A y,y in p-p scattering. The first step in the experimental design was the development of a hard real-time data acquisition system. To meet stringent latency requirements, the capabilities of Windows XP had to be augmented with a real-time subsystem. The remote control feature of the data acquisition enables users to operate it from any place via an internet connection. The data acquisition proved its reliability in several beam times without any failures. The analysis of the data showed the presence of 1/f noise which substantially limits the quality of our measurements. The origin of 1/f noise was traced and found to be the Barkhausen noise from the ferrite core of the beam current transformer (BCT). A global weighted fitting technique based on a modified Wiener-Khinchin method was developed and used to suppress the influence of 1/f noise, which increased the error bar of the results by a factor 3. This is the only deviation from our expectations. The results are presented and discussed. (orig.)

Test of feasibility of a novel high precision test of time reversal invariance

Energy Technology Data Exchange (ETDEWEB)

Samuel, Deepak

2007-07-01

The first results of a feasibility test of a novel high precision test of time reversal invariance are reported. The Time Reversal Invariance test at COSY (TRIC) was planned to measure the time reversal violating observable A{sub y,xz} with an accuracy of 10{sup -6} in proton-deuteron (p-d) scattering. A novel technique for measuring total cross sections is introduced and the achievable precision of this measuring technique is tested. The correlation coefficient A{sub y,y} in p-d scattering fakes a time-reversal violating effect. This work reports the feasibility test of the novel method in the measurement of A{sub y,y} in p-p scattering. The first step in the experimental design was the development of a hard real-time data acquisition system. To meet stringent latency requirements, the capabilities of Windows XP had to be augmented with a real-time subsystem. The remote control feature of the data acquisition enables users to operate it from any place via an internet connection. The data acquisition proved its reliability in several beam times without any failures. The analysis of the data showed the presence of 1/f noise which substantially limits the quality of our measurements. The origin of 1/f noise was traced and found to be the Barkhausen noise from the ferrite core of the beam current transformer (BCT). A global weighted fitting technique based on a modified Wiener-Khinchin method was developed and used to suppress the influence of 1/f noise, which increased the error bar of the results by a factor 3. This is the only deviation from our expectations. The results are presented and discussed. (orig.)

Characterization of Camptothecin-induced Genomic Changes in the Camptothecin-resistant T-ALL-derived Cell Line CPT-K5

DEFF Research Database (Denmark)

Kjeldsen, Eigil; Nielsen, Christine J F; Roy, Amit

2018-01-01

-K5 and its parental cell line. We identified copy number alterations affecting genes important for maintaining genome integrity and reducing CPT-induced DNA damage. We show for the first time that short tandem repeats are targets for TOP1 cleavage, that can be differentially stimulated by CPT.......Acquisition of resistance to topoisomerase I (TOP1)-targeting camptothecin (CPT) derivatives is a major clinical problem. Little is known about the underlying chromosomal and genomic mechanisms. We characterized the CPT-K5 cell line expressing mutant CPT-resistant TOP1 and its parental T......-cell derived acute lymphoblastic leukemia CPT-sensitive RPMI-8402 cell line by karyotyping and molecular genetic methods, including subtractive oligo-based array comparative genomic hybridization (soaCGH) analysis. Karyotyping revealed that CPT-K5 cells had acquired additional structural aberrations...

Evaluating Forecasts, Narratives and Policy Using a Test of Invariance

Directory of Open Access Journals (Sweden)

Jennifer L. Castle

2017-09-01

Full Text Available Economic policy agencies produce forecasts with accompanying narratives, and base policy changes on the resulting anticipated developments in the target variables. Systematic forecast failure, defined as large, persistent deviations of the outturns from the numerical forecasts, can make the associated narrative false, which would in turn question the validity of the entailed policy implementation. We establish when systematic forecast failure entails failure of the accompanying narrative, which we call forediction failure, and when that in turn implies policy invalidity. Most policy regime changes involve location shifts, which can induce forediction failure unless the policy variable is super exogenous in the policy model. We propose a step-indicator saturation test to check in advance for invariance to policy changes. Systematic forecast failure, or a lack of invariance, previously justified by narratives reveals such stories to be economic fiction.

Apparent CPT violation in neutrino oscillation experiments

International Nuclear Information System (INIS)

Engelhardt, Netta; Nelson, Ann E.; Walsh, Jonathan R.

2010-01-01

We consider searching for light sterile fermions and new forces by using long baseline oscillations of neutrinos and antineutrinos. A new light sterile state and/or a new force can lead to apparent CPT violation in muon neutrino and antineutrino oscillations. As an example, we present an economical model of neutrino masses containing a sterile neutrino. The potential from the standard model weak neutral current gives rise to a difference between the disappearance probabilities of neutrinos and antineutrinos, when mixing with a light sterile neutrino is considered. The addition of a B-L interaction adds coherently to the neutrino current potential and increases the difference between neutrino and antineutrino disappearance. We find that this model can improve the fit to the results of MINOS for both neutrinos and antineutrinos, without any CPT violation, and that the regions of parameter space which improve the fit are within experimental constraints.

Status of time reversal invariance

International Nuclear Information System (INIS)

Henley, E.M.

1989-01-01

Time Reversal Invariance is introduced, and theories for its violation are reviewed. The present experimental and theoretical status of Time Reversal Invariance and tests thereof will be presented. Possible future tests will be discussed. 30 refs., 2 figs., 1 tab

Cosmological CPT violation and CMB polarization measurements

Energy Technology Data Exchange (ETDEWEB)

Xia, Jun-Qing, E-mail: xia@sissa.it [Scuola Internazionale Superiore di Studi Avanzati, Via Bonomea 265, I-34136 Trieste (Italy)

2012-01-01

In this paper we study the possibility of testing Charge-Parity-Time Reversal (CPT) symmetry with cosmic microwave background (CMB) experiments. We consider two kinds of Chern-Simons (CS) term, electromagnetic CS term and gravitational CS term, and study their effects on the CMB polarization power spectra in detail. By combining current CMB polarization measurements, the seven-year WMAP, BOOMERanG 2003 and BICEP observations, we obtain a tight constraint on the rotation angle Δα = −2.28±1.02 deg (1 σ), indicating a 2.2 σ detection of the CPT violation. Here, we particularly take the systematic errors of CMB measurements into account. After adding the QUaD polarization data, the constraint becomes −1.34 < Δα < 0.82 deg at 95% confidence level. When comparing with the effect of electromagnetic CS term, the gravitational CS term could only generate TB and EB power spectra with much smaller amplitude. Therefore, the induced parameter ε can not be constrained from the current polarization data. Furthermore, we study the capabilities of future CMB measurements, Planck and CMBPol, on the constraints of Δα and ε. We find that the constraint of Δα can be significantly improved by a factor of 15. Therefore, if this rotation angle effect can not be taken into account properly, the constraints of cosmological parameters will be biased obviously. For the gravitational CS term, the future Planck data still can not constrain ε very well, if the primordial tensor perturbations are small, r < 0.1. We need the more accurate CMBPol experiment to give better constraint on ε.

Testing the time-invariance of fundamental constants using microwave spectroscopy on cold diatomic radicals

NARCIS (Netherlands)

Bethlem, H.L.; Ubachs, W.M.G.

2009-01-01

The recently demonstrated methods to cool and manipulate neutral molecules offer new possibilities for precision tests of fundamental physics theories. We here discuss the possibility of testing the time-invariance of fundamental constants using near degeneracies between rotational levels in the

Distinct CPT-induced deaths in lung cancer cells caused by clathrin-mediated internalization of CP micelles

Science.gov (United States)

Liu, Yu-Sheng; Cheng, Ru-You; Lo, Yu-Lun; Hsu, Chin; Chen, Su-Hwei; Chiu, Chien-Chih; Wang, Li-Fang

2016-02-01

We previously synthesized a chondroitin sulfate-graft-poly(ε-caprolactone) copolymer (H-CP) with a high content of poly(ε-caprolactone) (18.7 mol%), which self-assembled in water into a rod-like micelle to encapsulate hydrophobic camptothecin (CPT) in the core (micelle/CPT) for tumor-targeted drug delivery. As a result of the recognition of the micelle by CD44, the micelle/CPT entered CRL-5802 cells efficiently and released CPT efficaciously, resulting in higher tumor suppression than commercial CPT-11. In this study, H1299 cells were found to have a higher CD44 expression than CRL-5802 cells. However, the lower CD44-expressing CRL-5802 cells had a higher percentage of cell death and higher cellular uptake of the micelle/CPT than the higher CD44-expressing H1299 cells. Examination of the internalization pathway of the micelle/CPT in the presence of different endocytic chemical inhibitors showed that the CRL-5802 cells involved clathrin-mediated endocytosis, which was not found in the H1299 cells. Analysis of the cell cycle of the two cell lines exposed to the micelle/CPT revealed that the CRL-5802 cells arrested mainly in the S phase and the H1299 cells arrested mainly in the G2-M phase. A consistent result was also found in the evaluation of γ-H2AX expression, which was about three-fold higher in the CRL-5802 cells than in the H1299 cells. A near-infrared dye, IR780, was encapsulated into the micelle to observe the in vivo biodistribution of the micelle/IR780 in tumor-bearing mice. The CRL-5802 tumor showed a higher fluorescence intensity than the H1299 tumor at any tracing time after 1 h. Thus we tentatively concluded that CRL-5802 cells utilized the clathrin-mediated internalization pathway and arrested in the S phase on exposure to the micelle/CPT; all are possible reasons for the better therapeutic outcome in CRL-5802 cells than in H1299 cells.We previously synthesized a chondroitin sulfate-graft-poly(ε-caprolactone) copolymer (H-CP) with a high content of

Testing measurement invariance of the Learning Programme Management and Evaluation scale across academic achievement

Directory of Open Access Journals (Sweden)

Maelekanyo C. Mulaudzi

2016-10-01

Full Text Available Orientation: Measurement invariance is one of the most precarious aspects of the scale development process without which the interpretation of research findings on population subgroups may be ambiguous and even invalid. Besides tests for validity and reliability, measurement invariance represents the hallmark for psychometric compliance of a new measuring instrument and provides the basis for inference of research findings across a range of relevant population sub-groups. Research purpose: This study tested the measurement invariance of a Learning Programme Management and Evaluation (LPME scale across levels of academic achievement. Motivation for the study: It is important for any researcher involved in new scale development to ensure that the measurement instrument and its underlying constructs have proper structural alignment and that they both have the same level of meaning and significance across comparable heterogeneous groups. Research design, approach and method: A quantitative, non-experimental, cross-sectional survey design was used, and data were obtained from 369 participants who were selected from three public sector organisations using a probabilistic simple random sampling technique. The Statistical Package for Social Sciences and Analysis of Moment Structures software (versions 21.0.0 were used to analyse the data. Main findings: The findings show that all the four invariance models tested have achieved acceptable goodness-of-fit indices. Furthermore, the findings show that the factorial structure of the LPME scale and the meaning of its underlying constructs are invariant across different levels of academic achievement for human resource development (HRD practitioners and learners or apprentices involved in occupational learning programmes. Practical implications: The findings of this study suggest practical implications for HRD scholars as they are enabled to make informed decisional balance comparisons involving educational

Test of time-reversal invariance at COSY (TRIC)

Energy Technology Data Exchange (ETDEWEB)

Eversheim, D., E-mail: evershei@hiskp.uni-bonn.de; Valdau, Yu. [University Bonn, Helmholtz Institut fuer Strahlen- und Kernphysik (Germany); Lorentz, B. [Forschungszentrum Juelich, Institut fuer Kernphysik (Germany)

2013-03-15

At the Cooler Synchrotron COSY a novel (P-even, T-odd) null test of time-reversal invariance to an accuracy of 10{sup - 6} is planned as an internal target transmission experiment. The parity conserving time-reversal violating observable is the total cross-section asymmetry A{sub y,xz}. This quantity is measured using a polarized proton beam with an energy of 135 MeV and an internal tensor polarized deuteron target from the PAX atomic beam source. The reaction rate will be measured by means of an integrating beam current transformer. Thus, in this experiment the cooler synchroton ring serves as ideal forward spectrometer, as a detector, and an accelerator.

Finally! A valid test of configural invariance using permutation in multigroup CFA

NARCIS (Netherlands)

Jorgensen, T.D.; Kite, B.A.; Chen, P.-Y.; Short, S.D.; van der Ark, L.A.; Wiberg, M.; Culpepper, S.A.; Douglas, J.A.; Wang, W.-C.

2017-01-01

In multigroup factor analysis, configural measurement invariance is accepted as tenable when researchers either (a) fail to reject the null hypothesis of exact fit using a χ2 test or (b) conclude that a model fits approximately well enough, according to one or more alternative fit indices (AFIs).

A CPT-even and Lorentz-Violating nonminimal coupling in the Dirac equation

Energy Technology Data Exchange (ETDEWEB)

Ferreira Junior, Manoel; Casana, M.R.; Santos, Frederico E.P. dos; Silva, E.O. [UFMA, Sao Luis (Brazil); Passos, E. [UFCG, Campina Grande, PB (Brazil)

2013-07-01

Full text: The Standard Model Extension (SME) has been the usual framework for investigating signals of Lorentz violation in physical systems. It is the natural framework for studying properties of physical systems with Lorentz-violation since it includes Lorentz-violating terms in all sectors of the minimal standard model. The Lorentz-violating (LV) terms are generated as vacuum expectation values of tensors defined in a high energy scale. This framework has inspired a great deal of investigation in recent years. Such works encompass several distinct aspects involving fermion systems and radiative corrections, CPT- probing experiments, the electromagnetic CPT- and Lorentz-odd term, the 19 electromagnetic CPT-even coefficients. Recently, some studies involving higher dimensional operators have also been reported with great interest, including nonminimal interactions. These many contributions have elucidated the effects induced by Lorentz violation and served to set up stringent upper bounds on the LV coefficients. In the present work, we propose a new CPT-even, dimension-five, nonminimal coupling linking the fermionic and gauge fields in the context of the Dirac equation, involving the CPT-even tensor of the gauge term of the SME. By considering the nonrelativistic limit of the modified Dirac equation, we explicitly evaluate the new contributions to the nonrelativistic Hamiltonian. These new terms imply a direct correction on the anomalous magnetic moment, a kind of electrical Zeeman-like effect on the atomic spectrum, and a Rashba-like coupling term. These effects are then used to impose upper bounds on the magnitude of the non minimally coupled LV coefficients at the level of 1 part in 10{sub 16}. (author)

A CPT-even and Lorentz-Violating nonminimal coupling in the Dirac equation

International Nuclear Information System (INIS)

Ferreira Junior, Manoel; Casana, M.R.; Santos, Frederico E.P. dos; Silva, E.O.; Passos, E.

2013-01-01

Full text: The Standard Model Extension (SME) has been the usual framework for investigating signals of Lorentz violation in physical systems. It is the natural framework for studying properties of physical systems with Lorentz-violation since it includes Lorentz-violating terms in all sectors of the minimal standard model. The Lorentz-violating (LV) terms are generated as vacuum expectation values of tensors defined in a high energy scale. This framework has inspired a great deal of investigation in recent years. Such works encompass several distinct aspects involving fermion systems and radiative corrections, CPT- probing experiments, the electromagnetic CPT- and Lorentz-odd term, the 19 electromagnetic CPT-even coefficients. Recently, some studies involving higher dimensional operators have also been reported with great interest, including nonminimal interactions. These many contributions have elucidated the effects induced by Lorentz violation and served to set up stringent upper bounds on the LV coefficients. In the present work, we propose a new CPT-even, dimension-five, nonminimal coupling linking the fermionic and gauge fields in the context of the Dirac equation, involving the CPT-even tensor of the gauge term of the SME. By considering the nonrelativistic limit of the modified Dirac equation, we explicitly evaluate the new contributions to the nonrelativistic Hamiltonian. These new terms imply a direct correction on the anomalous magnetic moment, a kind of electrical Zeeman-like effect on the atomic spectrum, and a Rashba-like coupling term. These effects are then used to impose upper bounds on the magnitude of the non minimally coupled LV coefficients at the level of 1 part in 10 16 . (author)

Effects of perfluorodecanoic(PFDA) and perfluorooctanoic (PFOA) acids on hepatic carnitine palmitoyltransferase (CPT) activity in rats

International Nuclear Information System (INIS)

Vanden Heuvel, J.P.; Kuslikis, B.I.; Peterson, R.E.

1990-01-01

PFDA has been hypothesized to cause a diversion of fatty acids from oxidation toward esterification in rat liver. Normal regulation of this partitioning is exerted by CPT, an enzyme inhibited by several peroxisome proliferators. Effects of the peroxisome proliferators PFDA and PFOA on hepatic mitochondrial fatty acid oxidation and CPT activity were examined. PFDA or PFOA added to isolated rat liver mitochondria in concentrations of 0.2, 2, 20 and 200 μg per mg mitochondrial protein had no effect on CPT activity nor on mitochondrial oxidation of [1- 14 C] palmitoyl-CoA or [1- 14 C] palmitoyl-carnitine (quantitated by 14 CO 2 plus acid soluble 14 C production). Three days after rats were treated with PFDA or PFOA (37.5 or 150 μmol/kg, ip) or vehicle, liver mitochondria were isolated. Mitochondrial oxidation of [1- 14 C] palmitoyl-CoA or [1- 14 C]palmitoyl-carnitine was unaffected by PFDA and PFOA. CPT activity and inhibition of CPT activity by malonyl-CoA was also unaffected by PFDA and PFOA. Therefore, PFDA and PFOA did not have a major inhibitory effect on hepatic mitochondrial oxidation of palmitoyl-CoA or palmitoyl-carnitine, nor did they interfere with hepatic CPT activity either in vitro or in vivo

Effect of Cellular Location of Human Carboxylesterase 2 on CPT-11 Hydrolysis and Anticancer Activity.

Directory of Open Access Journals (Sweden)

Yuan-Ting Hsieh

Full Text Available CPT-11 is an anticancer prodrug that is clinically used for the treatment of metastatic colorectal cancer. Hydrolysis of CPT-11 by human carboxylesterase 2 (CE2 generates SN-38, a topoisomerase I inhibitor that is the active anti-tumor agent. Expression of CE2 in cancer cells is under investigation for the tumor-localized activation of CPT-11. CE2 is normally expressed in the endoplasmic reticulum of cells but can be engineered to direct expression of active enzyme on the plasma membrane or as a secreted form. Although previous studies have investigated different locations of CE2 expression in cancer cells, it remains unclear if CE2 cellular location affects CPT-11 anticancer activity. In the present study, we directly compared the influence of CE2 cellular location on substrate hydrolysis and CPT-11 cytotoxicity. We linked expression of CE2 and enhanced green fluorescence protein (eGFP via a foot-and-mouth disease virus 2A (F2A peptide to facilitate fluorescence-activated cell sorting to achieve similar expression levels of ER-located, secreted or membrane-anchored CE2. Soluble CE2 was detected in the medium of cells that expressed secreted and membrane-anchored CE2, but not in cells that expressed ER-retained CE2. Cancer cells that expressed all three forms of CE2 were more sensitive to CPT-11 as compared to unmodified cancer cells, but the membrane-anchored and ER-retained forms of CE2 were consistently more effective than secreted CE2. We conclude that expression of CE2 in the ER or on the membrane of cancer cells is suitable for enhancing CPT-11 anticancer activity.

Normal Levels of Plasma Free Carnitine and Acylcarnitines in Follow-Up Samples From a Presymptomatic Case of Carnitine Palmitoyl Transferase 1 (CPT1) Deficiency Detected Through Newborn Screening in Denmark

DEFF Research Database (Denmark)

Borch, Luise; Lund, Allan; Wibrand, Flemming

2011-01-01

of presymptomatic CPT1A deficiency detected through newborn screening in Denmark with diagnostic levels of carnitine and acylcarnitines in the initial dried blood spot. Levels of plasma-free carnitine and acylcarnitines in follow-up samples were normal, but reverted to diagnostic levels when the patient developed...... clinical symptoms at the age of 8 months. At that time, a diagnosis of CPT1A deficiency was confirmed by sequence analysis of the CPT1A gene revealing homozygosity for a novel c.167C>T variation in exon 3. Enzyme activity measurements showed a relatively mild enzyme defect with a decreased residual enzyme...... activity of 17–25%. We conclude that CPT1A gene testing and/or enzyme assay is mandatory to confirm an abnormal newborn screen suggesting CPT1A deficiency to avoid delayed diagnoses....

Antimatter Experiments

CERN Multimedia

2004-01-01

Antimatter should behave in identical fashion to matter if a form of spacetime symmetry called CPT invariance holds. Two experiments at CERN near Geneva are testing this hypothesis using antihydrogen atoms

Synthesizing Modular Invariants for Synchronous Code

Directory of Open Access Journals (Sweden)

Pierre-Loic Garoche

2014-12-01

Full Text Available In this paper, we explore different techniques to synthesize modular invariants for synchronous code encoded as Horn clauses. Modular invariants are a set of formulas that characterizes the validity of predicates. They are very useful for different aspects of analysis, synthesis, testing and program transformation. We describe two techniques to generate modular invariants for code written in the synchronous dataflow language Lustre. The first technique directly encodes the synchronous code in a modular fashion. While in the second technique, we synthesize modular invariants starting from a monolithic invariant. Both techniques, take advantage of analysis techniques based on property-directed reachability. We also describe a technique to minimize the synthesized invariants.

Testing Measurement Invariance of the Students' Affective Characteristics Model across Gender Sub-Groups

Science.gov (United States)

Demir, Ergül

2017-01-01

In this study, the aim was to construct a significant structural measurement model comparing students' affective characteristics with their mathematic achievement. According to this model, the aim was to test the measurement invariances between gender sub-groups hierarchically. This study was conducted as basic and descriptive research. Secondary…

Metabolomic profiling reveals a role for CPT1c in neuronal oxidative metabolism

OpenAIRE

Lee, Jieun; Wolfgang, Michael J

2012-01-01

Abstract Background Carnitine Palmitoyltransferase-1c (CPT1c) is a neuron specific homologue of the carnitine acyltransferase family of enzymes. CPT1 isoenzymes transfer long chain acyl groups to carnitine. This constitutes a rate setting step for mitochondrial fatty acid beta-oxidation by facilitating the initial step in acyl transfer to the mitochondrial matrix. In general, neurons do not heavily utilize fatty acids for bioenergetic needs and definitive enzymatic activity has been unable to...

Mutation in CPT1C Associated With Pure Autosomal Dominant Spastic Paraplegia.

Science.gov (United States)

Rinaldi, Carlo; Schmidt, Thomas; Situ, Alan J; Johnson, Janel O; Lee, Philip R; Chen, Ke-Lian; Bott, Laura C; Fadó, Rut; Harmison, George H; Parodi, Sara; Grunseich, Christopher; Renvoisé, Benoît; Biesecker, Leslie G; De Michele, Giuseppe; Santorelli, Filippo M; Filla, Alessandro; Stevanin, Giovanni; Dürr, Alexandra; Brice, Alexis; Casals, Núria; Traynor, Bryan J; Blackstone, Craig; Ulmer, Tobias S; Fischbeck, Kenneth H

2015-05-01

The family of genes implicated in hereditary spastic paraplegias (HSPs) is quickly expanding, mostly owing to the widespread availability of next-generation DNA sequencing methods. Nevertheless, a genetic diagnosis remains unavailable for many patients. To identify the genetic cause for a novel form of pure autosomal dominant HSP. We examined and followed up with a family presenting to a tertiary referral center for evaluation of HSP for a decade until August 2014. Whole-exome sequencing was performed in 4 patients from the same family and was integrated with linkage analysis. Sanger sequencing was used to confirm the presence of the candidate variant in the remaining affected and unaffected members of the family and screen the additional patients with HSP. Five affected and 6 unaffected participants from a 3-generation family with pure adult-onset autosomal dominant HSP of unknown genetic origin were included. Additionally, 163 unrelated participants with pure HSP of unknown genetic cause were screened. Mutation in the neuronal isoform of carnitine palmitoyl-transferase (CPT1C) gene. We identified the nucleotide substitution c.109C>T in exon 3 of CPT1C, which determined the base substitution of an evolutionarily conserved Cys residue for an Arg in the gene product. This variant strictly cosegregated with the disease phenotype and was absent in online single-nucleotide polymorphism databases and in 712 additional exomes of control participants. We showed that CPT1C, which localizes to the endoplasmic reticulum, is expressed in motor neurons and interacts with atlastin-1, an endoplasmic reticulum protein encoded by the ATL1 gene known to be mutated in pure HSPs. The mutation, as indicated by nuclear magnetic resonance spectroscopy studies, alters the protein conformation and reduces the mean (SD) number (213.0 [46.99] vs 81.9 [14.2]; P lipid droplets on overexpression in cells. We also observed a reduction of mean (SD) lipid droplets in primary cortical neurons

CPT Special Report: Survey of Ph.D. Programs in Chemistry.

Science.gov (United States)

Journal of Chemical Education, 1997

1997-01-01

Presents preliminary results from a survey taken by the American Chemical Society (ACS) Committee on Professional Training (CPT) to determine the current practices among 155 Ph.D. programs in chemistry. (DKM)

Feedback-Driven Dynamic Invariant Discovery

Science.gov (United States)

Zhang, Lingming; Yang, Guowei; Rungta, Neha S.; Person, Suzette; Khurshid, Sarfraz

2014-01-01

Program invariants can help software developers identify program properties that must be preserved as the software evolves, however, formulating correct invariants can be challenging. In this work, we introduce iDiscovery, a technique which leverages symbolic execution to improve the quality of dynamically discovered invariants computed by Daikon. Candidate invariants generated by Daikon are synthesized into assertions and instrumented onto the program. The instrumented code is executed symbolically to generate new test cases that are fed back to Daikon to help further re ne the set of candidate invariants. This feedback loop is executed until a x-point is reached. To mitigate the cost of symbolic execution, we present optimizations to prune the symbolic state space and to reduce the complexity of the generated path conditions. We also leverage recent advances in constraint solution reuse techniques to avoid computing results for the same constraints across iterations. Experimental results show that iDiscovery converges to a set of higher quality invariants compared to the initial set of candidate invariants in a small number of iterations.

High Energy Astrophysics Tests of Lorentz Invariance and Quantum Gravity Models

Science.gov (United States)

Stecker, Floyd W.

2012-01-01

High energy astrophysics observations provide the best possibilities to detect a very small violation of Lorentz invariance such as may be related to the structure of space-time near the Planck scale of approx.10(exp -35) m. I will discuss the possible signatures of Lorentz invariance violation (LIV) that can be manifested by observing of the spectra, polarization, and timing of gamma-rays from active galactic nuclei and gamma-ray bursts. Other sensitive tests are provided by observations of the spectra of ultrahigh energy cosmic rays and neutrinos. Using the latest data from the Pierre Auger Observatory one can already derive an upper limit of 4.5 x 10(exp -23) on the fraction of LIV at a Lorentz factor of approx. 2 x 10(exp 11). This result has fundamental implications for quantum gravity models. I will also discuss the possibilities of using more sensitive space-based detection techniques to improve searches for LIV in the future. I will also discuss how the LIV formalism casts doubt on the OPERA superluminal neutrino claim.

Tests of Lorentz and CPT violation with MiniBooNE neutrino oscillation excesses

International Nuclear Information System (INIS)

Katori, Teppei

2014-01-01

Lorentz and CPT symmetry violaton is a predicted phenomenon of Planck–scale physics. Various types of data are analyzed to search for Lorentz violation under the Standard–Model Extension (SME) framework, including neutrino oscillation data. MiniBooNE is a short–baseline neutrino oscillation experiment at Fermilab. The measured excesses from MiniBooNE cannot be reconciled within the neutrino Standard Model (vSM); thus it might be a signal of new physics, such as Lorentz violation. We have analyzed the sidereal time dependence of MiniBooNE data for signals of the possible sidereal time dependence of the ocillation signals. we find that the v e appearance data prefer a sidereal time–independent solution, and the v-bar e appearance data slightly prefer a sidereal time–dependent solution, however, the statistical significance is not high to claim the discovery. Limits of order 10 −20 GeV are placed on combinations of SME coefficients

Testing the Invariance of the National Health and Nutrition Examination Survey's Sexual Behavior Questionnaire Across Gender, Ethnicity/Race, and Generation.

Science.gov (United States)

Zhou, Anne Q; Hsueh, Loretta; Roesch, Scott C; Vaughn, Allison A; Sotelo, Frank L; Lindsay, Suzanne; Klonoff, Elizabeth A

2016-02-01

Federal and state policies are based on data from surveys that examine sexual-related cognitions and behaviors through self-reports of attitudes and actions. No study has yet examined their factorial invariance--specifically, whether the relationship between items assessing sexual behavior and their underlying construct differ depending on gender, ethnicity/race, or age. This study examined the factor structure of four items from the sexual behavior questionnaire part of the National Health and Nutrition Examination Survey (NHANES). As NHANES provided different versions of the survey per gender, invariance was tested across gender to determine whether subsequent tests across ethnicity/race and generation could be done across gender. Items were not invariant across gender groups so data files for women and men were not collapsed. Across ethnicity/race for both genders, and across generation for women, items were configurally invariant, and exhibited metric invariance across Latino/Latina and Black participants for both genders. Across generation for men, the configural invariance model could not be identified so the baseline models were examined. The four item one factor model fit well for the Millennial and GenerationX groups but was a poor fit for the baby boomer and silent generation groups, suggesting that gender moderated the invariance across generation. Thus, comparisons between ethnic/racial and generational groups should not be made between the genders or even within gender. Findings highlight the need for programs and interventions that promote a more inclusive definition of "having had sex."

Ramsey-CPT spectrum with the Faraday effect and its application to atomic clocks

International Nuclear Information System (INIS)

Tian Yuan; Gu Si-Hong; Tan Bo-Zhong; Yang Jing; Zhang Yi

2015-01-01

A method that obtains the Ramsey-coherent population trapping (CPT) spectrum with the Faraday effect is investigated. An experiment is implemented to detect the light polarization components generated from the Faraday effect. The experimental results agree with the theoretical calculations based on the Liouville equation. By comparing with the method without using the Faraday effect, the potential of this method for a CPT-based atomic clock is assessed. The results indicate that this method should improve the short-term frequency stability by several times. (paper)

Effect of Drainage Conditions on Cone Penetration Testing in Silty Soils

DEFF Research Database (Denmark)

Poulsen, Rikke; Nielsen, Benjaminn Nordahl; Ibsen, Lars Bo

2011-01-01

This paper discusses the challenges that occur when performing Cone Penetration Tests (CPT) in silty soil due to changes in drainage conditions. In this paper, CPT results from various papers and researchers are collected and interpreted. Results from cone penetrations tests with various penetrat......This paper discusses the challenges that occur when performing Cone Penetration Tests (CPT) in silty soil due to changes in drainage conditions. In this paper, CPT results from various papers and researchers are collected and interpreted. Results from cone penetrations tests with various...

On the phase of ε and the NA31 bound on CPT violation

International Nuclear Information System (INIS)

Lavoura, L.

1992-01-01

In this paper the author discusses the theoretical prediction for the phase of the CP-violating parameter ε, and the experimental bound on the CPT-violating contribution to that parameter. The author concludes that, if one neglects theoretical prejudices and only takes into account the experimental data, the phase of ε may differ by as much as four degrees from the superweak phase. The present experimental bound on CPT violation cannot be much strengthened if one does not first obtain better bounds on the CP violation in the three-pion decay modes

Rotating optical cavity experiment testing Lorentz invariance at the 10-17 level

International Nuclear Information System (INIS)

Herrmann, S.; Senger, A.; Moehle, K.; Nagel, M.; Kovalchuk, E. V.; Peters, A.

2009-01-01

We present an improved laboratory test of Lorentz invariance in electrodynamics by testing the isotropy of the speed of light. Our measurement compares the resonance frequencies of two orthogonal optical resonators that are implemented in a single block of fused silica and are rotated continuously on a precision air bearing turntable. An analysis of data recorded over the course of one year sets a limit on an anisotropy of the speed of light of Δc/c∼1x10 -17 . This constitutes the most accurate laboratory test of the isotropy of c to date and allows to constrain parameters of a Lorentz violating extension of the standard model of particle physics down to a level of 10 -17 .

Test of time-reversal invariance at COSY

Energy Technology Data Exchange (ETDEWEB)

Valdau, Yury [Helmholtz Institut fuer Strahlen- und Kernphysik, Bonn Univ. (Germany); National Research Center ' ' Kurchatov Institute' ' Petersburg Nuclear Physics Institute B.P. Konstantinov, Gatchina (Russian Federation); Eversheim, Dieter [Helmholtz Institut fuer Strahlen- und Kernphysik, Bonn Univ. (Germany); Lorentz, Bernd [Forschungszentrum Juelich, Institute fuer Kernphysik (Germany)

2016-07-01

The experiment to test the Time Reversal Invariance at Cosy (TRIC) is under the preparation by the PAX collaboration. It is planned to improve present limit on the T-odd P-even interaction by at least one order of magnitude using a unique genuine null observable available in double polarized proton-deuteron scattering. The TRIC experiment is planned as a transmission experiment using a tensor polarized deuterium target placed at the internal target place of the Cooler-Synchrotron COSY-Juelich. Total double polarized cross section will be measured observing a beam current change due to the interaction of a polarized proton beam with an internal tensor polarized deuterium target from the PAX atomic beam source. Hence, in this experiment COSY will be used as an accelerator, detector and ideal zero degree spectrometer. In addition to the high intensity polarized proton beam and high density polarized deuterium target, a new high precision beam current measurement system will be prepared for the TRIC experiment. In this report status of all the activities of PAX collaboration towards realization of the TRIC experiment will be presented.

Standard test method for electrochemical critical pitting temperature testing of stainless steels

CERN Document Server

American Society for Testing and Materials. Philadelphia

1999-01-01

1.1 This test method covers a procedure for the evaluation of the resistance of stainless steel and related alloys to pitting corrosion based on the concept of the determination of a potential independent critical pitting temperature (CPT). 1.2 This test methods applies to wrought and cast products including but not restricted to plate, sheet, tubing, bar, forgings, and welds, (see Note 1). Note 1—Examples of CPT measurements on sheet, plate, tubing, and welded specimens for various stainless steels can be found in Ref (1). See the research reports (Section 14). 1.3 The standard parameters recommended in this test method are suitable for characterizing the CPT of austenitic stainless steels and other related alloys with a corrosion resistance ranging from that corresponding to solution annealed UNS S31600 (Type 316 stainless steel) to solution annealed UNS S31254 (6 % Mo stainless steel). 1.4 This test method may be extended to stainless steels and other alloys related to stainless steel that have a CPT...

Exploration of CPT violation via time-dependent geometric quantities embedded in neutrino oscillation through fluctuating matter

Energy Technology Data Exchange (ETDEWEB)

Wang, Zisheng, E-mail: zishengwang@yahoo.com [College of Physics and Communication Electronics, Jiangxi Normal University, Nanchang 330022 (China); Institute of Applied Physics and Materials Engineering, University of Macau, Macao SAR (China); Pan, Hui, E-mail: huipan@umac.mo [Institute of Applied Physics and Materials Engineering, University of Macau, Macao SAR (China)

2017-02-15

We propose a new approach to explore CPT violation of neutrino oscillations through a fluctuating matter based on time-dependent geometric quantities. By mapping the neutrino oscillations onto a Poincaré sphere structure, we obtain an analytic solution of master equation and further define the geometric quantities, i.e., radius of Poincaré sphere and geometric phase. We find that the mixing process between electron and muon neutrinos can be described by the radius of Poincaré sphere that depends on the intrinsic CP-violating angle. Such a radius reveals a dynamic mechanism of CPT-violation, i.e., both spontaneous symmetry breaking and Majorana–Dirac neutrino confusion. We show that the time-dependent geometric phase can be used to find the neutrino nature and observe the CPT-violation because it is strongly enhanced under the neutrino propagation. We further show that the time-dependent geometric phase can be easily detected by simulating the neutrino oscillation based on fluctuating magnetic fields in nuclear magnetic resonance, which makes the experimental observation of CPT-violation possible in the neutrino mixing and oscillations.

Invariance Signatures: Characterizing contours by their departures from invariance

OpenAIRE

Squire, David; Caelli, Terry M.

1997-01-01

In this paper, a new invariant feature of two-dimensional contours is reported: the Invariance Signature. The Invariance Signature is a measure of the degree to which a contour is invariant under a variety of transformations, derived from the theory of Lie transformation groups. It is shown that the Invariance Signature is itself invariant under shift, rotation and scaling of the contour. Since it is derived from local properties of the contour, it is well-suited to a neural network implement...

$K^{0} \\leftrightharpoons \\overline{K}^0$ transitions monitored by strong interactions a new determination of the $K_{L} - K_{S}$ mass difference

CERN Document Server

Angelopoulos, Angelos; Backenstoss, Gerhard; Bargassa, P; Behnke, O; Benelli, A; Bertin, V; Blanc, F; Bloch, P; Carlson, P J; Carroll, M; Cawley, E; Chertok, M B; Danielsson, M; Dejardin, M; Derré, J; Ealet, A; Eleftheriadis, C; Fetscher, W; Fidecaro, Maria; Filipcic, A; Francis, D; Fry, J; Gabathuler, Erwin; Gamet, R; Gerber, H J; Go, A; Haselden, A; Haymen, P J; Henry-Coüannier, F; Hollander, R W; Jon-And, K; Kettle, P R; Kokkas, P; Kreuger, R; Le Gac, R; Leimgruber, F; Mandic, I; Manthos, N; Marel, Gérard; Mikuz, M; Miller, J; Montanet, François; Müller, A; Nakada, Tatsuya; Pagels, B; Papadopoulos, I M; Pavlopoulos, P; Polivka, G; Rickenbach, R; Roberts, B L; Ruf, T; Sakelliou, L; Schäfer, M; Schaller, L A; Schietinger, T; Schopper, A; Tauscher, Ludwig; Thibault, C; Touchard, F; Touramanis, C; van Eijk, C W E; Vlachos, S; Weber, P; Wigger, O; Wolter, M; Zavrtanik, D; Zimmerman, D

2001-01-01

The CPLEAR set-up (modified) has been used to determine the K/sub L/- K/sub S/ mass difference by a method where neutral-kaon strangeness oscillations are monitored through kaon strong interactions, rather than semileptonic decays, thus requiring no assumptions on CPT invariance for the decay amplitudes. The result, Delta m= (0.5343+or-0.0063/sub stat/+or-0.0025/sub syst/)*10/sup 10/ h(cross) /s, provides a valuable input for CPT tests. (22 refs).

Model-based classification of CPT data and automated lithostratigraphic mapping for high-resolution characterization of a heterogeneous sedimentary aquifer.

Science.gov (United States)

Rogiers, Bart; Mallants, Dirk; Batelaan, Okke; Gedeon, Matej; Huysmans, Marijke; Dassargues, Alain

2017-01-01

Cone penetration testing (CPT) is one of the most efficient and versatile methods currently available for geotechnical, lithostratigraphic and hydrogeological site characterization. Currently available methods for soil behaviour type classification (SBT) of CPT data however have severe limitations, often restricting their application to a local scale. For parameterization of regional groundwater flow or geotechnical models, and delineation of regional hydro- or lithostratigraphy, regional SBT classification would be very useful. This paper investigates the use of model-based clustering for SBT classification, and the influence of different clustering approaches on the properties and spatial distribution of the obtained soil classes. We additionally propose a methodology for automated lithostratigraphic mapping of regionally occurring sedimentary units using SBT classification. The methodology is applied to a large CPT dataset, covering a groundwater basin of ~60 km2 with predominantly unconsolidated sandy sediments in northern Belgium. Results show that the model-based approach is superior in detecting the true lithological classes when compared to more frequently applied unsupervised classification approaches or literature classification diagrams. We demonstrate that automated mapping of lithostratigraphic units using advanced SBT classification techniques can provide a large gain in efficiency, compared to more time-consuming manual approaches and yields at least equally accurate results.

Model-based classification of CPT data and automated lithostratigraphic mapping for high-resolution characterization of a heterogeneous sedimentary aquifer.

Directory of Open Access Journals (Sweden)

Bart Rogiers

Full Text Available Cone penetration testing (CPT is one of the most efficient and versatile methods currently available for geotechnical, lithostratigraphic and hydrogeological site characterization. Currently available methods for soil behaviour type classification (SBT of CPT data however have severe limitations, often restricting their application to a local scale. For parameterization of regional groundwater flow or geotechnical models, and delineation of regional hydro- or lithostratigraphy, regional SBT classification would be very useful. This paper investigates the use of model-based clustering for SBT classification, and the influence of different clustering approaches on the properties and spatial distribution of the obtained soil classes. We additionally propose a methodology for automated lithostratigraphic mapping of regionally occurring sedimentary units using SBT classification. The methodology is applied to a large CPT dataset, covering a groundwater basin of ~60 km2 with predominantly unconsolidated sandy sediments in northern Belgium. Results show that the model-based approach is superior in detecting the true lithological classes when compared to more frequently applied unsupervised classification approaches or literature classification diagrams. We demonstrate that automated mapping of lithostratigraphic units using advanced SBT classification techniques can provide a large gain in efficiency, compared to more time-consuming manual approaches and yields at least equally accurate results.

Testing Measurement Invariance across Groups of Children with and without Attention-Deficit/ Hyperactivity Disorder: Applications for Word Recognition and Spelling Tasks.

Science.gov (United States)

Lúcio, Patrícia S; Salum, Giovanni; Swardfager, Walter; Mari, Jair de Jesus; Pan, Pedro M; Bressan, Rodrigo A; Gadelha, Ary; Rohde, Luis A; Cogo-Moreira, Hugo

2017-01-01

Although studies have consistently demonstrated that children with attention-deficit/hyperactivity disorder (ADHD) perform significantly lower than controls on word recognition and spelling tests, such studies rely on the assumption that those groups are comparable in these measures. This study investigates comparability of word recognition and spelling tests based on diagnostic status for ADHD through measurement invariance methods. The participants ( n = 1,935; 47% female; 11% ADHD) were children aged 6-15 with normal IQ (≥70). Measurement invariance was investigated through Confirmatory Factor Analysis and Multiple Indicators Multiple Causes models. Measurement invariance was attested in both methods, demonstrating the direct comparability of the groups. Children with ADHD were 0.51 SD lower in word recognition and 0.33 SD lower in spelling tests than controls. Results suggest that differences in performance on word recognition and spelling tests are related to true mean differences based on ADHD diagnostic status. Implications for clinical practice and research are discussed.

Quantum tests for the linearity and permutation invariance of Boolean functions

Energy Technology Data Exchange (ETDEWEB)

Hillery, Mark [Department of Physics, Hunter College of the City University of New York, 695 Park Avenue, New York, New York 10021 (United States); Andersson, Erika [SUPA, School of Engineering and Physical Sciences, Heriot-Watt University, Edinburgh EH14 4AS (United Kingdom)

2011-12-15

The goal in function property testing is to determine whether a black-box Boolean function has a certain property or is {epsilon}-far from having that property. The performance of the algorithm is judged by how many calls need to be made to the black box in order to determine, with high probability, which of the two alternatives is the case. Here we present two quantum algorithms, the first to determine whether the function is linear and the second to determine whether it is symmetric (invariant under permutations of the arguments). Both require order {epsilon}{sup -2/3} calls to the oracle, which is better than known classical algorithms. In addition, in the case of linearity testing, if the function is linear, the quantum algorithm identifies which linear function it is. The linearity test combines the Bernstein-Vazirani algorithm and amplitude amplification, while the test to determine whether a function is symmetric uses projective measurements and amplitude amplification.

Contribution of CPLEAR to the physics of the neutral kaon system

CERN Document Server

Pavlopoulos, P; Alhalel, T; Angelopoulos, Angelos; Apostolakis, Alcibiades J; Aslanides, Elie; Backenstoss, Gerhard; Bee, C P; Behnke, O; Benelli, A; Bertin, V; Blanc, F; Bloch, P; Carlson, P J; Carroll, M; Carvalho, J; Cawley, E; Charalambous, S; Chardin, G; Chertok, M B; Cody, A; Danielsson, M; Dejardin, M; Derré, J; Ealet, A; Eckart, B; Eleftheriadis, C; Evangelou, I; Faravel, L; Fassnacht, P; Felder, C; Ferreira-Marques, R; Fetscher, W; Fidecaro, Maria; Filipcic, A; Francis, D; Fry, J; Gabathuler, Erwin; Gamet, R; Garreta, D; Gerber, H J; Go, A; Guyot, C; Haselden, A; Hayman, P J; Henry-Coüannier, F; Hollander, R W; Hubert, E; Jon-And, K; Kettle, P R; Kochowski, Claude; Kokkas, P; Kreuger, R; Le Gac, R; Leimgruber, F; Liolios, A; Machado, E; Mandic, I; Manthos, N; Marel, Gérard; Mikuz, M; Miller, J; Montanet, François; Nakada, Tatsuya; Pagels, B; Papadopoulos, I M; Pinto da Cunha, J; Policarpo, Armando; Polivka, G; Rickenbach, R; Roberts, B L; Ruf, T; Sakelliou, L; Sanders, M P; Santoni, C; Schäfer, M; Schaller, L A; Schietinger, T; Schopper, A; Schune, P; Tauscher, Ludwig; Thibault, C; Touchard, F; Touramanis, C; Triantis, F A; Van Beveren, E; van Eijk, C W E; Vlachos, S; Weber, P; Wigger, O; Wolter, M; Yéche, C; Zavrtanik, D; Zimmerman, D

1999-01-01

We present the physics results of the CP-- and CPT--violation measurements performed by CPLEAR. CPLEAR has experimentally determined for the first time, the violation of T invariance and is able to disentangle all the CP-- and CPT--violating quantities from each other. This allows each of the CPT violating parameters to be determined with a precision of a few $10^{-4}$ and, in particular, the mass and width equality between the \\kn and \\knb to be tested down to the level of $10^{-19}$ GeV. Moreover, the precision of the CPLEAR measurements allows us to probe for the first time physics on a scale approaching the Planck mass.

Feasibility of using cone penetrometer truck (CPT) to install time domain reflectometry (TDR) and fiber optic slope failure detectors in pavement structures.

Science.gov (United States)

2011-02-01

A new method of cable installation using a heavy-duty Cone Penetration Test : (CPT) truck was developed and practiced successfully in this study. The coaxial and fiber : optic cables were pushed along with the cone rods by the hydraulic system integr...

Use of the Cognitive Performance Test for Identifying Deficits in Hospitalized Older Adults

Directory of Open Access Journals (Sweden)

Alison Douglas

2012-01-01

Full Text Available Objectives. The Cognitive Performance Test (CPT is a functional assessment for persons with dementia. The study purpose was to evaluate the reliability, discriminant, and concurrent validity of the CPT. Method. The CPT was tested against other measures of cognition (Standardized Mini Mental Status Exam (SMMSE and Assessment of Motor and Process Skills-Process scale (AMPS-Process. Participants were persons 65 years and older admitted to a geriatric rehabilitation unit (n=47. Results. The CPT correlated moderately with measures of cognition (SMMSE r=0.47, AMPS-Process r=0.53, P<0.01, and ADL burden of care (FIM r=0.32, P<0.05. Scores were not affected by age, sex, years of education, motor skills, or comorbidities. The CPT differentiated between impaired and unimpaired individuals differently from other measures. Conclusion. While CPT appears related to other measures of cognition, test interpretation requires noting the variability between CPT scores and those measures.

In situ pore-pressure evolution during dynamic CPT measurements in soft sediments of the western Baltic Sea

Science.gov (United States)

Seifert, Annedore; Stegmann, Sylvia; Mörz, Tobias; Lange, Matthias; Wever, Thomas; Kopf, Achim

2008-08-01

We present in situ strength and pore-pressure measurements from 57 dynamic cone penetration tests in sediments of Mecklenburg ( n = 51), Eckernförde ( n = 2) and Gelting ( n = 4) bays, western Baltic Sea, characterised by thick mud layers and partially free microbial gas resulting from the degradation of organic material. In Mecklenburg and Eckernförde bays, sediment sampling by nine gravity cores served sedimentological characterisation, analyses of geotechnical properties, and laboratory shear tests. At selected localities, high-resolution echo-sounder profiles were acquired. Our aim was to deploy a dynamic cone penetrometer (CPT) to infer sediment shear strength and cohesion of the sea bottom as a function of fluid saturation. The results show very variable changes in pore pressure and sediment strength during the CPT deployments. The majority of the CPT measurements ( n = 54) show initially negative pore-pressure values during penetration, and a delayed response towards positive pressures thereafter. This so-called type B pore-pressure signal was recorded in all three bays, and is typically found in soft muds with high water contents and undrained shear strengths of 1.6-6.4 kPa. The type B signal is further affected by displacement of sediment and fluid upon penetration of the lance, skin effects during dynamic profiling, enhanced consolidation and strength of individual horizons, the presence of free gas, and a dilatory response of the sediment. In Mecklenburg Bay, the remaining small number of CPT measurements ( n = 3) show a well-defined peak in both pore pressure and cone resistance during penetration, i.e. an initial marked increase which is followed by exponential pore-pressure decay during dissipation. This so-called type A pore-pressure signal is associated with normally consolidated mud, with indurated clay layers showing significantly higher undrained shear strength (up to 19 kPa). In Eckernförde and Gelting bays pore-pressure response type B is

Constraints of a Parity-Conserving Interaction

Science.gov (United States)

van Oers, Willem T. H.

2002-09-01

Time-Reversal-Invariance non-conservation has for the first time been unequivocally demonstrated in a direct measurement at CPLEAR. One then can ask the question: What about tests of time-reversal-invariance in systems other than the kaon system? Tests of time-reversal-invariance can be distinguished as belonging to two classes: the first one deals with time-reversal-invariance-non-conserving (T-odd)/parity violating (P-odd) interactions, while the second one deals with T-odd/P-even interactions (assuming CPT conservation this implies C-conjugation non-conservation). Limits on a T-odd/P-odd interaction follow from measurements of the electric dipole moment of the neutron (room for further experimentation?

Measurements of Direct CP Violation, CPT Symmetry, and Other Parameters in the Neutral Kaon System

Energy Technology Data Exchange (ETDEWEB)

Worcester, Elizabeth Turner [Univ. of Chicago, IL (United States)

2007-12-01

The authors present precision measurements of the direct CP violation parameter, Re(ϵ'/ϵ), the kaon parameters, Δm and τ_S, and the CPT tests, Φ_± and ΔΦ, in neutral kaon decays. These results are based on the full dataset collected by the KTeV experiment at Fermi National Accelerator Laboratory during 1996, 1997, and 1999. This dataset contains ~ 15 million K → π⁰π⁰ decays and ~ 69 million K → π⁺π^- decays. They describe significant improvements to the precision of these measurements relative to previous KTeV analyses. They find Re(ϵ'/ϵ = [19.2 ± 1.1(stat) ± 1.8(syst)] x 10^-4, Δm = (5265 ± 10) x 10⁶ hs^-1, and τ_S = (89.62 ± 0.05) x 10^-12 s. They measure Φ_± = (44.09 ± 1.00)° and ΔΦ = (0.29 ± 0.31)°; these results are consistent with CPT symmetry.

Testing measurement invariance of the Depression, Anxiety, and Stress Scales (DASS-21) across four countries.

Science.gov (United States)

Scholten, Saskia; Velten, Julia; Bieda, Angela; Zhang, Xiao Chi; Margraf, Jürgen

2017-11-01

The rising burden of mental and behavioral disorders has become a global challenge (Murray et al., 2012). Measurement invariant clinical instruments are necessary for the assessment of relevant symptoms across countries. The present study tested the measurement invariance of the 21-item version of the Depression, Anxiety, and Stress Scales (DASS; Lovibond & Lovibond, 1995b) in Poland, Russia, the United Kingdom (U.K.), and the United States of America (U.S.). Telephone interviews were conducted with population-based samples (nPL = 1003, nRU = 3020, nU.K. = 1002, nU.S. = 1002). The DASS-21 shows threshold measurement invariance. Comparisons of latent means did not indicate differences between U.K. and U.S. However, Polish and Russian samples reported more depressive symptoms compared with U.K. and U.S. samples; the Russian sample had the highest levels of anxiety symptoms and the Polish sample demonstrated the highest stress levels. The DASS-21 can be recommended to meaningfully compare the relationships between variables across groups and to compare latent means in Polish-, Russian-, and English-speaking populations. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

Ananas comosus L. Leaf Phenols and p-Coumaric Acid Regulate Liver Fat Metabolism by Upregulating CPT-1 Expression

Directory of Open Access Journals (Sweden)

Weidong Xie

2014-01-01

Full Text Available In this study, we aimed to investigate the effect and action mechanisms of pineapple leaf phenols (PLPs on liver fat metabolism in high-fat diet-fed mice. Results show that PLP significantly reduced abdominal fat and liver lipid accumulation in high-fat diet-fed mice. The effects of PLP were comparable with those of FB. Furthermore, at the protein level, PLP upregulated the expression of carnitine palmitoyltransferase 1 (CPT-1, whereas FB had no effects on CPT-1 compared with the HFD controls. Regarding mRNA expression, PLP mainly promoted the expression of CPT-1, PGC1a, UCP-1, and AMPK in the mitochondria, whereas FB mostly enhanced the expression of Ech1, Acox1, Acaa1, and Ehhadh in peroxisomes. PLP seemed to enhance fat metabolism in the mitochondria, whereas FB mainly exerted the effect in peroxisomes. In addition, p-coumaric acid (CA, one of the main components from PLP, significantly inhibited fat accumulation in oleic acid-induced HepG2 cells. CA also significantly upregulated CPT-1 mRNA and protein expressions in HepG2 cells. We, firstly, found that PLP enhanced liver fat metabolism by upregulating CPT-1 expression in the mitochondria and might be promising in treatment of fatty liver diseases as alternative natural products. CA may be one of the active components of PLP.

The 5-choice continuous performance test: evidence for a translational test of vigilance for mice.

Directory of Open Access Journals (Sweden)

Jared W Young

Full Text Available Attentional dysfunction is related to functional disability in patients with neuropsychiatric disorders such as schizophrenia, bipolar disorder, and Alzheimer's disease. Indeed, sustained attention/vigilance is among the leading targets for new medications designed to improve cognition in schizophrenia. Although vigilance is assessed frequently using the continuous performance test (CPT in humans, few tests specifically assess vigilance in rodents.We describe the 5-choice CPT (5C-CPT, an elaboration of the 5-choice serial reaction (5CSR task that includes non-signal trials, thus mimicking task parameters of human CPTs that use signal and non-signal events to assess vigilance. The performances of C57BL/6J and DBA/2J mice were assessed in the 5C-CPT to determine whether this task could differentiate between strains. C57BL/6J mice were also trained in the 5CSR task and a simple reaction-time (RT task involving only one choice (1CRT task. We hypothesized that: 1 C57BL/6J performance would be superior to DBA/2J mice in the 5C-CPT as measured by the sensitivity index measure from signal detection theory; 2 a vigilance decrement would be observed in both strains; and 3 RTs would increase across tasks with increased attentional load (1CRT task<5CSR task<5C-CPT.C57BL/6J mice exhibited superior SI levels compared to DBA/2J mice, but with no difference in accuracy. A vigilance decrement was observed in both strains, which was more pronounced in DBA/2J mice and unaffected by response bias. Finally, we observed increased RTs with increased attentional load, such that 1CRT task<5CSR task<5C-CPT, consistent with human performance in simple RT, choice RT, and CPT tasks. Thus we have demonstrated construct validity for the 5C-CPT as a measure of vigilance that is analogous to human CPT studies.

Plasma cortisol levels in response to a cold pressor test did not predict appetite or ad libitum test meal intake in obese women.

Science.gov (United States)

Geliebter, Allan; Gibson, Charlisa D; Hernandez, Dominica B; Atalayer, Deniz; Kwon, Anne; Lee, Michelle I; Mehta, Nandini; Phair, Donna; Gluck, Marci E

2012-12-01

Heightened cortisol response to stress due to hyperactivation of the hypothalamic-pituitary-adrenal (HPA) axis may stimulate appetite and food intake. In this study, we assessed cortisol responsivity to a cold pressor test (CPT) as well as appetite ratings and subsequent test meal intake (TMI) in obese women. Following an overnight fast on two counterbalanced days, 20 obese women immersed their non-dominant hand for 2min in ice water (CPT) or warm water (WW) as a control. Plasma cortisol (ng/ml), heart rate, and blood pressure, as well as ratings of stress, pain, and appetite, were serially acquired. An ad libitum liquid meal was offered at 45min and intake measured covertly. Fasting cortisol was higher at 15min (mean peak cortisol) following the CPT compared to WW. Higher stress was reported at 2 and 15min for the CPT compared to WW. Pain, an indirect marker of the acute stress, systolic and diastolic blood pressure increased following the CPT at 2min compared to WW. Hunger decreased after the CPT at 2 and 15min, and desire to eat ratings were lower following CPT compared to WW. Subjects did not have greater test meal intake (TMI) following CPT compared to WW. There was also no significant relationship between cortisol levels following stress and TMI, indicating that cortisol did not predict subsequent intake in obese women. Copyright © 2012 Elsevier Ltd. All rights reserved.

Invariant subspaces

CERN Document Server

Radjavi, Heydar

2003-01-01

This broad survey spans a wealth of studies on invariant subspaces, focusing on operators on separable Hilbert space. Largely self-contained, it requires only a working knowledge of measure theory, complex analysis, and elementary functional analysis. Subjects include normal operators, analytic functions of operators, shift operators, examples of invariant subspace lattices, compact operators, and the existence of invariant and hyperinvariant subspaces. Additional chapters cover certain results on von Neumann algebras, transitive operator algebras, algebras associated with invariant subspaces,

What’s hampering measurement invariance: Detecting non-invariant items using clusterwise simultaneous component analysis

Directory of Open Access Journals (Sweden)

Kim eDe Roover

2014-06-01

Full Text Available The issue of measurement invariance is ubiquitous in the behavioral sciences nowadays as more and more studies yield multivariate multigroup data. When measurement invariance cannot be established across groups, this is often due to different loadings on only a few items. Within the multigroup CFA framework, methods have been proposed to trace such non-invariant items, but these methods have some disadvantages in that they require researchers to run a multitude of analyses and in that they imply assumptions that are often questionable. In this paper, we propose an alternative strategy which builds on clusterwise simultaneous component analysis (SCA. Clusterwise SCA, being an exploratory technique, assigns the groups under study to a few clusters based on differences and similarities in the covariance matrices, and thus based on the component structure of the items. Non-invariant items can then be traced by comparing the cluster-specific component loadings via congruence coefficients, which is far more parsimonious than comparing the component structure of all separate groups. In this paper we present a heuristic for this procedure. Afterwards, one can return to the multigroup CFA framework and check whether removing the non-invariant items or removing some of the equality restrictions for these items, yields satisfactory invariance test results. An empirical application concerning cross-cultural emotion data is used to demonstrate that this novel approach is useful and can co-exist with the traditional CFA approaches.

Measurement invariance versus selection invariance: Is fair selection possible?

NARCIS (Netherlands)

Borsboom, D.; Romeijn, J.W.; Wicherts, J.M.

2008-01-01

This article shows that measurement invariance (defined in terms of an invariant measurement model in different groups) is generally inconsistent with selection invariance (defined in terms of equal sensitivity and specificity across groups). In particular, when a unidimensional measurement

Measurement invariance versus selection invariance : Is fair selection possible?

NARCIS (Netherlands)

Borsboom, Denny; Romeijn, Jan-Willem; Wicherts, Jelte M.

This article shows that measurement invariance (defined in terms of an invariant measurement model in different groups) is generally inconsistent with selection invariance (defined in terms of equal sensitivity and specificity across groups). In particular, when a unidimensional measurement

PSI collapse and relativistic covariance

International Nuclear Information System (INIS)

Costa de Beauregard, Olivier

1980-01-01

We call macrorelativistic a theory invariant under the orthochronous Lorentz group and obeying the 'factlike' principle of retarded causality, and microrelativistic a theory invariant under the full Lorentz group and CPT symmetric. The Einstein correlations either direct (non-separability of measurements issuing from a common preparation) or reversed (non-separability of preparations producing a common measurement) are incompatible with the macro-, but compatible with the microrelativity. We assume that fundamental physics is fully Lorentz and CPT invariant (the transition to macrophysics introducing a 'factlike asymmetry) and consequently define the collapse-and-retrocollapse concept [fr

The CPT1C 5'UTR contains a repressing upstream open reading frame that is regulated by cellular energy availability and AMPK.

Directory of Open Access Journals (Sweden)

Ines Lohse

Full Text Available BACKGROUND: Translational control is utilized as a means of regulating gene expression in many species. In most cases, posttranscriptional regulatory mechanisms play an important role in stress response pathways and can lead to dysfunctional physiology if blocked by mutations. Carnitine Palmitoyltransferase 1 C (CPT1C, the brain-specific member of the CPT 1 family, has previously been shown to be involved in regulating metabolism in situations of energy surplus. PRINCIPAL FINDINGS: Sequence analysis of the CPT1C mRNA revealed that it contains an upstream open reading frame (uORF in the 5' UTR of its mRNA. Using CPT1C 5' UTR/luciferase constructs, we investigated the role of the uORF in translational regulation. The results presented here show that translation from the CPT1C main open reading frame (mORF is repressed by the presence of the uORF, that this repression is relieved in response to specific stress stimuli, namely glucose deprivation and palmitate-BSA treatment, and that AMPK inhibition can relieve this uORF-dependent repression. SIGNIFICANCE: The fact that the mORF regulation is relieved in response to a specific set of stress stimuli rather than general stress response, hints at an involvement of CPT1C in cellular energy-sensing pathways and provides further evidence for a role of CPT1C in hypothalamic regulation of energy homeostasis.

Testing Lorentz invariance of dark matter with satellite galaxies

Energy Technology Data Exchange (ETDEWEB)

Bettoni, Dario [Institut für Theoretische Physik, Ruprecht-Karls-Universität Heidelberg, Philosophenweg 16, 69120 Heidelberg (Germany); Nusser, Adi [Physics Department and the Asher Space Science Institute—Technion, Haifa 32000 (Israel); Blas, Diego; Sibiryakov, Sergey, E-mail: d.bettoni@thphys.uni-heidelberg.de, E-mail: adi@physics.technion.ac.il, E-mail: diego.blas@cern.ch, E-mail: sergey.sibiryakov@cern.ch [Theoretical Physics Department, CERN, CH-1211 Geneva 23 (Switzerland)

2017-05-01

We develop the framework for testing Lorentz invariance in the dark matter sector using galactic dynamics. We consider a Lorentz violating (LV) vector field acting on the dark matter component of a satellite galaxy orbiting in a host halo. We introduce a numerical model for the dynamics of satellites in a galactic halo and for a galaxy in a rich cluster to explore observational consequences of such an LV field. The orbital motion of a satellite excites a time dependent LV force which greatly affects its internal dynamics. Our analysis points out key observational signatures which serve as probes of LV forces. These include modifications to the line of sight velocity dispersion, mass profiles and shapes of satellites. With future data and a more detailed modeling these signatures can be exploited to constrain a new region of the parameter space describing the LV in the dark matter sector.

CPT conservation and atmospheric neutrinos in the MINOS far detector

International Nuclear Information System (INIS)

Becker, Bernard Raymond

2006-01-01

The MINOS Far Detector is a 5400 ton iron calorimeter located at the Soudan state park in Soudan Minnesota. The MINOS far detector can observe atmospheric neutrinos and separate charge current ν μ and (bar ν) μ interactions by using a 1.4 T magnetic field to identify the charge of the produced muon. The CPT theorem requires that neutrinos and anti-neutrinos oscillate in the same way. In a fiducial exposure of 5.0 kilo-ton years a total of 41 candidate neutrino events are observed with an expectation of 53.1 ± 7.6(system.) ± 7.2(stat.) unoscillated events or 31.6 ± 4.7(system.) ± 5.6(stat.) events with Δm 2 = 2.4 x 10 -3 eV 2 , sin 2 (2θ) = 1.0 as oscillation parameters. These include 28 events which can have there charge identified with high confidence. These 28 events consist of 18 events consistent with being produced by ν μ and 10 events being consistent with being produced by (bar ν) μ . No evidence of CPT violation is observed

An efficient probe of the cosmological CPT violation

Energy Technology Data Exchange (ETDEWEB)

Zhao, Gong-Bo; Wang, Yuting [National Astronomy Observatories, Chinese Academy of Science, Beijing, 100012 (China); Xia, Jun-Qing [Key Laboratory of Particle Astrophysics, Institute of High Energy Physics, Chinese Academy of Science, P. O. Box 918-3, Beijing 100049 (China); Li, Mingzhe [Interdisciplinary Center for Theoretical Study, University of Science and Technology of China, Hefei, Anhui 230026 (China); Zhang, Xinmin, E-mail: gbzhao@nao.cas.cn, E-mail: ytwang@nao.cas.cn, E-mail: xiajq@ihep.ac.cn, E-mail: limz@ustc.edu.cn, E-mail: xmzhang@ihep.ac.cn [Theory Division, Institute of High Energy Physics, Chinese Academy of Science, P. O. Box 918-4, Beijing 100049 (China)

2015-07-01

We develop an efficient method based on the linear regression algorithm to probe the cosmological CPT violation using the CMB polarisation data. We validate this method using simulated CMB data and apply it to recent CMB observations. We find that a combined data sample of BICEP1 and BOOMERanG 2003 favours a nonzero isotropic rotation angle at 2.3σ confidence level, i.e., α-bar =−3.3{sup o}±1.4{sup o} (68% CL) with systematics included.

Compare diagnostic tests using transformation-invariant smoothed ROC curves⋆

Science.gov (United States)

Tang, Liansheng; Du, Pang; Wu, Chengqing

2012-01-01

Receiver operating characteristic (ROC) curve, plotting true positive rates against false positive rates as threshold varies, is an important tool for evaluating biomarkers in diagnostic medicine studies. By definition, ROC curve is monotone increasing from 0 to 1 and is invariant to any monotone transformation of test results. And it is often a curve with certain level of smoothness when test results from the diseased and non-diseased subjects follow continuous distributions. Most existing ROC curve estimation methods do not guarantee all of these properties. One of the exceptions is Du and Tang (2009) which applies certain monotone spline regression procedure to empirical ROC estimates. However, their method does not consider the inherent correlations between empirical ROC estimates. This makes the derivation of the asymptotic properties very difficult. In this paper we propose a penalized weighted least square estimation method, which incorporates the covariance between empirical ROC estimates as a weight matrix. The resulting estimator satisfies all the aforementioned properties, and we show that it is also consistent. Then a resampling approach is used to extend our method for comparisons of two or more diagnostic tests. Our simulations show a significantly improved performance over the existing method, especially for steep ROC curves. We then apply the proposed method to a cancer diagnostic study that compares several newly developed diagnostic biomarkers to a traditional one. PMID:22639484

Impediments to Enhancement of CPT-11 Anticancer Activity by E. coli Directed Beta-Glucuronidase Therapy

Science.gov (United States)

Hsieh, Yuan-Ting; Chen, Kai-Chuan; Cheng, Chiu-Min; Cheng, Tian-Lu; Tao, Mi-Hua; Roffler, Steve R.

2015-01-01

CPT-11 is a camptothecin analog used for the clinical treatment of colorectal adenocarcinoma. CPT-11 is converted into the therapeutic anti-cancer agent SN-38 by liver enzymes and can be further metabolized to a non-toxic glucuronide SN-38G, resulting in low SN-38 but high SN-38G concentrations in the circulation. We previously demonstrated that adenoviral expression of membrane-anchored beta-glucuronidase could promote conversion of SN-38G to SN-38 in tumors and increase the anticancer activity of CPT-11. Here, we identified impediments to effective tumor therapy with E. coli that were engineered to constitutively express highly active E. coli beta-glucuronidase intracellularly to enhance the anticancer activity of CPT-11. The engineered bacteria, E. coli (lux/βG), could hydrolyze SN-38G to SN-38, increased the sensitivity of cultured tumor cells to SN-38G by about 100 fold and selectively accumulated in tumors. However, E. coli (lux/βG) did not more effectively increase CPT-11 anticancer activity in human tumor xenografts as compared to non-engineered E. coli. SN-38G conversion to SN-38 by E. coli (lux/βG) appeared to be limited by slow uptake into bacteria as well as by segregation of E. coli in necrotic regions of tumors that may be relatively inaccessible to systemically-administered drug molecules. Studies using a fluorescent glucuronide probe showed that significantly greater glucuronide hydrolysis could be achieved in mice pretreated with E. coli (lux/βG) by direct intratumoral injection of the glucuronide probe or by intratumoral lysis of bacteria to release intracellular beta-glucuronidase. Our study suggests that the distribution of beta-glucuronidase, and possibly other therapeutic proteins, in the tumor microenvironment might be an important barrier for effective bacterial-based tumor therapy. Expression of secreted therapeutic proteins or induction of therapeutic protein release from bacteria might therefore be a promising strategy to enhance anti

Preparation, characterization, and cytotoxicity of CPT/Fe2O3-embedded PLGA ultrafine composite fibers: a synergistic approach to develop promising anticancer material

Directory of Open Access Journals (Sweden)

Amna T

2012-03-01

Full Text Available Touseef Amna1, M Shamshi Hassan2, Ki-Taek Nam2, Yang You Bing3, Nasser AM Barakat2, Myung-Seob Khil2, Hak Yong Kim1,21Center for Healthcare Technology Development, 2Department of Organic Materials and Fiber Engineering, Chonbuk National University, Jeonju, Korea; 3Animal Science and Technology College, Henan University of Science and Technology, Luoyang, ChinaAbstract: The aim of this study was to fabricate camptothecin/iron(III oxide (CPT/Fe2O3-loaded poly(D,L-lactide-co-glycolide (PLGA composite mats to modulate the CPT release and to improve the structural integrity and antitumor activity of the released drug. The CPT/ Fe2O3-loaded PLGA ultrafine fibers were prepared for the first time by electrospinning a composite solution of CPT/Fe2O3 and neat PLGA (4 weight percent. The physicochemical characterization of the electrospun composite mat was carried out by scanning electron microscopy, energy dispersive X-ray spectroscopy, electron probe microanalysis, thermogravimetry, transmission electron microscopy, ultraviolet-visible spectroscopy, and X-ray diffraction pattern. The medicated composite fibers were evaluated for their cytotoxicity on C2C12 cells using Cell Counting Kit-8 assay (Sigma-Aldrich Corporation, St Louis, MO. The in vitro studies indicated a slow and prolonged release over a period of 96 hours with mild initial burst. Scanning electron microscopy, thermogravimetry, and X-ray diffraction studies confirmed the interaction of CPT/Fe2O3 with the PLGA matrix and showed that the crystallinity of CPT decreased after loading. Incorporation of CPT in the polymer media affected both the morphology and the size of the CPT/Fe2O3-loaded PLGA composite fibers. Electron probe microanalysis and energy dispersive X-ray spectroscopy results confirmed well-oriented composite ultrafine fibers with good incorporation of CPT/Fe2O3. The cytotoxicity results illustrate that the pristine PLGA did not exhibit noteworthy cytotoxicity; conversely, the CPT

Testing measurement invariance of composites using partial least squares

NARCIS (Netherlands)

Henseler, Jörg; Ringle, Christian M.; Sarstedt, Marko

2016-01-01

Purpose Research on international marketing usually involves comparing different groups of respondents. When using structural equation modeling (SEM), group comparisons can be misleading unless researchers establish the invariance of their measures. While methods have been proposed to analyze

Validity of the Internet Addiction Test for Adolescents and Older Children (IAT-A): Tests of Measurement Invariance and Latent Mean Differences

Science.gov (United States)

Teo, Timothy; Kam, Chester

2014-01-01

Following the call to ensure the validity of instruments used to assess users' level of Internet usage, this study examined the factor structure of the Internet Addiction Test-Adolescence version (IAT-A) when applied to a sample of young children in a multicultural society and assessed whether the items in the IAT-A were invariant by gender and,…

Gamma-Ray, Cosmic Ray and Neutrino Tests of Lorentz Invariance and Quantum Gravity Models

Science.gov (United States)

Stecker, Floyd

2011-01-01

High-energy astrophysics observations provide the best possibilities to detect a very small violation of Lorentz invariance such as may be related to the structure of space-time near the Planck scale of approximately 10(exp -35) m. I will discuss here the possible signatures of Lorentz invariance violation (LIV) from observations of the spectra, polarization, and timing of gamma-rays from active galactic nuclei and gamma-ray bursts. Other sensitive tests are provided by observations of the spectra of ultrahigh energy cosmic rays and neutrinos. Using the latest data from the Pierre Auger Observatory one can already derive an upper limit of 4.5 x 10(exp -23) to the amount of LIV of at a proton Lorentz factor of approximately 2 x 10(exp 11). This result has fundamental implications for quantum gravity models. I will also discuss the possibilities of using more sensitive space based detection techniques to improve searches for LIV in the future.

Chronoprojective invariance of the five-dimensional Schroedinger formalism

International Nuclear Information System (INIS)

Perrin, M.; Burdet, G.; Duval, C.

1984-10-01

Invariance properties of the five-dimensional Schroedinger formalism describing a quantum test particle in the Newton-Cartan theory of gravitation are studied. The geometry which underlies these invariance properties is presented as a reduction of the 0(5,2) conformal geometry various applications are given

The Groenewold-Moyal Plane and its Quantum Physics

International Nuclear Information System (INIS)

Balachandran, A. P.; Padmanabhan, Pramod

2009-01-01

Quantum theories constructed on the noncommutative spacetime called the Groenewold-Moyal(GM) plane exhibit many interesting properties such as causality violation, Lorentz and CPT non-invariance and twisted statistics. Such violations lead to many striking features that may be tested experimentally. Thus these theories predict Pauli-forbidden transitions due to twisted statistics, anisotropies and acausal effects in the cosmic microwave background radiation in correlations of observables and Lorentz and CPT violations in scattering amplitudes. Such features of quantum physics on the GM plane are surveyed in this review.

Testing the Structural Invariance of the Africultural Coping Systems Inventory Across Three Samples of African Descent Populations

Science.gov (United States)

Utsey, Shawn O.; Brown, Christa; Bolden, Mark A.

2004-01-01

Confirmatory factor analysis was used to test the factorial invariance of the Africultural Coping Systems Inventory's (ACSI) measurement model and underlying factor structure across three independent and ethnically distinct samples of African descent populations. Results indicated that factor pattern coefficients of the ACSI's underlying…

Method for Predicting Void Ratio and Triaxial Friction Angle from Laboratory CPT at Shallow Depths

DEFF Research Database (Denmark)

Larsen, Kim André; Ibsen, Lars Bo

In this report an investigation of the relationship between the tip resistance, qc of a laboratory CPT-probe versus the relative density, Dr and friction angle, ∏ of Aalborg University Sand No. 0 is carried out. A method for estimating the relative density and the triaxial friction angle from...... the cone resistance of the laboratory probe is proposed. The suggested method deals with the fact that the friction angle is depended of the stress level especially at low stresses. The method includes a calibration of the cone resistance from the laboratory CPT at shallow depths i.e. low values of d...

Microstructural Evolution of Inconel 625 and Inconel 686CPT Weld Metal for Clad Carbon Steel Linepipe Joints: A Comparator Study

Science.gov (United States)

Maltin, Charles A.; Galloway, Alexander M.; Mweemba, Martin

2014-07-01

Microstructural evolution of Inconel 625 and Inconel 686CPT filler metals, used for the fusion welding of clad carbon steel linepipe, has been investigated and compared. The effects of iron dilution from the linepipe parent material on the elemental segregation potential of the filler metal chemistry have been considered. The results obtained provide significant evidence to support the view that, in Inconel 686CPT weld metal, the segregation of tungsten is a function of the level of iron dilution from the parent material. The data presented indicate that the incoherent phase precipitated in the Inconel 686CPT weld metal has a morphology that is dependent on tungsten enrichment and, therefore, iron dilution. Furthermore, in the same weld metal, a continuous network of finer precipitates was observed. The Charpy impact toughness of each filler metal was evaluated, and the results highlighted the superior impact toughness of the Inconel 625 weld metal over that of Inconel 686CPT.

Adiabatic invariants of the extended KdV equation

Energy Technology Data Exchange (ETDEWEB)

Karczewska, Anna [Faculty of Mathematics, Computer Science and Econometrics, University of Zielona Góra, Szafrana 4a, 65-246 Zielona Góra (Poland); Rozmej, Piotr, E-mail: p.rozmej@if.uz.zgora.pl [Institute of Physics, Faculty of Physics and Astronomy, University of Zielona Góra, Szafrana 4a, 65-246 Zielona Góra (Poland); Infeld, Eryk [National Centre for Nuclear Research, Hoża 69, 00-681 Warszawa (Poland); Rowlands, George [Department of Physics, University of Warwick, Coventry, CV4 7A (United Kingdom)

2017-01-30

When the Euler equations for shallow water are taken to the next order, beyond KdV, momentum and energy are no longer exact invariants. (The only one is mass.) However, adiabatic invariants (AI) can be found. When the KdV expansion parameters are zero, exact invariants are recovered. Existence of adiabatic invariants results from general theory of near-identity transformations (NIT) which allow us to transform higher order nonintegrable equations to asymptotically equivalent (when small parameters tend to zero) integrable form. Here we present a direct method of calculations of adiabatic invariants. It does not need a transformation to a moving reference frame nor performing a near-identity transformation. Numerical tests show that deviations of AI from constant values are indeed small. - Highlights: • We suggest a new and simple method for calculating adiabatic invariants of second order wave equations. • It is easy to use and we hope that it will be useful if published. • Interesting numerics included.

CPT conservation and atmospheric neutrinos in the MINOS far detector

Energy Technology Data Exchange (ETDEWEB)

Becker, Bernard Raymond [Univ. of Minnesota, Minneapolis, MN (United States)

2006-02-01

The MINOS Far Detector is a 5400 ton iron calorimeter located at the Soudan state park in Soudan Minnesota. The MINOS far detector can observe atmospheric neutrinos and separate charge current ν_μ and $\\bar{v}$_μ interactions by using a 1.4 T magnetic field to identify the charge of the produced muon. The CPT theorem requires that neutrinos and anti-neutrinos oscillate in the same way. In a fiducial exposure of 5.0 kilo-ton years a total of 41 candidate neutrino events are observed with an expectation of 53.1 ± 7.6(system.) ± 7.2(stat.) unoscillated events or 31.6 ± 4.7(system.) ± 5.6(stat.) events with Δm² = 2.4 x 10^-3 eV², sin²(2θ) = 1.0 as oscillation parameters. These include 28 events which can have there charge identified with high confidence. These 28 events consist of 18 events consistent with being produced by ν_μ and 10 events being consistent with being produced by $\\bar{v}$_μ. No evidence of CPT violation is observed.

Computational invariant theory

CERN Document Server

Derksen, Harm

2015-01-01

This book is about the computational aspects of invariant theory. Of central interest is the question how the invariant ring of a given group action can be calculated. Algorithms for this purpose form the main pillars around which the book is built. There are two introductory chapters, one on Gröbner basis methods and one on the basic concepts of invariant theory, which prepare the ground for the algorithms. Then algorithms for computing invariants of finite and reductive groups are discussed. Particular emphasis lies on interrelations between structural properties of invariant rings and computational methods. Finally, the book contains a chapter on applications of invariant theory, covering fields as disparate as graph theory, coding theory, dynamical systems, and computer vision. The book is intended for postgraduate students as well as researchers in geometry, computer algebra, and, of course, invariant theory. The text is enriched with numerous explicit examples which illustrate the theory and should be ...

Invariant submanifold flows

Energy Technology Data Exchange (ETDEWEB)

Olver, Peter J [School of Mathematics, University of Minnesota, Minneapolis, MN 55455 (United States)], E-mail: olver@math.umn.edu

2008-08-29

Given a Lie group acting on a manifold, our aim is to analyze the evolution of differential invariants under invariant submanifold flows. The constructions are based on the equivariant method of moving frames and the induced invariant variational bicomplex. Applications to integrable soliton dynamics, and to the evolution of differential invariant signatures, used in equivalence problems and object recognition and symmetry detection in images, are discussed.

$K^{0}-\\overline{K}^{0}$ mass and decay-width differences CPLEAR evaluation

CERN Document Server

Angelopoulos, Angelos; Aslanides, Elie; Backenstoss, Gerhard; Bargassa, P; Behnke, O; Benelli, A; Bertin, V; Blanc, F; Bloch, P; Carlson, P J; Carroll, M; Cawley, E; Chertok, M B; Danielsson, M; Dejardin, M; Derré, J; Ealet, A; Eleftheriadis, C; Fetscher, W; Fidecaro, Maria; Filipcic, A; Francis, D; Fry, J; Gabathuler, Erwin; Gamet, R; Gerber, H J; Go, A; Haselden, A; Hayman, P J; Henry-Coüannier, F; Hollander, R W; Jon-And, K; Kettle, P R; Kokkas, P; Kreuger, R; Le Gac, R; Leimgruber, F; Mandic, I; Manthos, N; Marel, Gérard; Mikuz, M; Miller, J; Montanet, François; Müller, A; Nakada, Tatsuya; Pagels, B; Papadopoulos, I M; Pavlopoulos, P; Polivka, G; Rickenbach, R; Roberts, B L; Ruf, T; Schäfer, M; Schaller, L A; Schietinger, T; Schopper, A; Tauscher, Ludwig; Thibault, C; Touchard, F; Touramanis, C; van Eijk, C W E; Vlachos, S; Weber, P; Wigger, O; Wolter, M; Zavrtanik, D; Zimmerman, D

1999-01-01

The CPT-violation parameters \\redd\\ and \\imd\\ determined recently by CPLEAR are used to evaluate the \\kn --\\knb\\ mass and decay-width differences, as given by the difference between the diagonal elements of the neutral-kaon mixing matrix $({\\mathrm M}-\\i\\Gamma/2)$. The results --- $({\\mathrm M}_{\\kn\\kn}-{\\mathrm M}_{\\knb\\knb}) = ( -1.5 \\pm 2.0 )\\times10^{-18}$ \\gev\\ and $(\\Gamma_{\\kn\\kn}-\\Gamma_{\\knb\\knb}) = ( 3.9 \\pm 4.2 )\\times 10^{-18}$ \\gev\\ --- are consistent with CPT invariance. The CPT invariance is also shown to hold within a few times $10^{-3}-10^{-4}$ for many of the amplitudes describing neutral-kaon decays to different final states.

[The utility of a continuous performance test embedded in virtual reality in measuring the effectiveness of MPH treatment in boys with ADHD].

Science.gov (United States)

Shriki, Liron; Weizer, Merav; Pollak, Yehuda; Weiss, Patricia L; Rizzo, Albert A; Gross-Tsur, Varda

2010-01-01

Continuous performance tasks (CPT) are popular in the diagnostic process of attention deficit hyperactivity disorder (ADHD), providing an objective measure of attention for a disorder with otherwise subjective criteria. The study aimed to: 1) examine whether the VR-CPT is sensitive to methylphenidate (MPH); 2) assess how the virtual reality (VR) environment is experienced. Twenty boys, 9-17 years, with ADHD underwent 3 CPTs: VR-CPT, the same CPT without VR (no VR-CPT) and the Test of Variables of Attention (T.O.V.A.). Subsequently, those with ADHD repeated the tests 1 hour following MPH ingestion. Immediately following the CPT, the subjects described their subjective experiences on the Short Feedback Questionnaire. Results were analyzed using ANOVA with repeated measures. MPH reduced the omission and commission errors on all tests to a similar degree. Subjective feelings of enjoyment were most positive for VR-CPT. The VR-CPT is a sensitive and user-friendly assessment tool for evaluating the effectiveness of MPH treatment in boys with ADHD.

CPT Profiling and Laboratory Data Correlations for Deriving of Selected Geotechnical Parameter

Directory of Open Access Journals (Sweden)

Bulko Roman

2015-12-01

Full Text Available Currently, can be seen a new trend in engineering geological survey, where laboratory analysis are replaced by in situ testing methods, which are more efficient and cost effective, and time saving too. A regular engineering geological survey cannot be provided by simple core drillings, macroscopic description (sometimes very subjective, and then geotechnical parameters are established based on indicative standardized values or archive values from previous geotechnical standards. The engineering geological survey is trustworthy if is composed of laboratory and in-situ testing supplemented by indirect methods of testing, [1]. The prevalence of rotary core drilling for obtaining laboratory soil samples from various depths (every 1 to 3 m, cannot be a more enhanced as continues evaluation of strata and properties e.g. by CPT Piezocone (every 1 cm. Core drillings survey generally uses small amounts of soil samples, but this is resulting to a lower representation of the subsoil and underestimation of parameters. Higher amounts of soil samples make laboratory testing time-consuming and results from this testing can be influenced by the storage and processing of the soil samples. Preference for geotechnical surveys with in situ testing is therefore a more suitable option. In situ testing using static and dynamic penetration tests can be used as a supplement or as a replacement for the (traditional methods of surveying.

Computer calculation of Witten's 3-manifold invariant

International Nuclear Information System (INIS)

Freed, D.S.; Gompf, R.E.

1991-01-01

Witten's 2+1 dimensional Chern-Simons theory is exactly solvable. We compute the partition function, a topological invariant of 3-manifolds, on generalized Seifert spaces. Thus we test the path integral using the theory of 3-manifolds. In particular, we compare the exact solution with the asymptotic formula predicted by perturbation theory. We conclude that this path integral works as advertised and gives an effective topological invariant. (orig.)

The current perception threshold test differentiates categories of mechanical neck disorder.

Science.gov (United States)

Uddin, Zakir; MacDermid, Joy C; Galea, Victoria; Gross, Anita R; Pierrynowski, Michael R

2014-07-01

Cross-sectional discriminative analysis. To determine whether current perception threshold (CPT) can differentiate between categories of patients with mechanical neck disorders (MNDs). Neck pain is the third most common musculoskeletal disorder and affects a third of all adults each year. It can present as neck pain without musculoskeletal signs, neck pain with musculoskeletal signs but no neurological signs, or neck pain with neurological signs. CPT testing can assess altered sensory perception that may reflect neurological changes. Patients with MNDs (n = 106) were classified into 3 groups, based on a standardized musculoskeletal examination process performed by an experienced physiotherapist who was blinded to CPT scores. The 3 groups were defined as neck pain without musculoskeletal signs (MND I) (n = 60), neck pain with musculoskeletal signs (MND II) (n = 29), and neck pain with neurological signs (MND III) (n = 17). A rapid protocol of CPT testing was performed at 3 frequencies (5, 250, and 2000 Hz), using 3 dermatomal locations on the hand. A 1-way analysis of variance with post hoc comparison and effect sizes was calculated to compare the mean CPT scores between the groups. A binary logistic-regression model was used to predict probability of higher CPT in MND III and to create a receiver-operating-characteristic curve. Mean CPT differed significantly across the 3 MND groups (MND I, 9.7; MND II, 10.6; and MND III, 11.8; Pabnormal CPT in MND III had an estimated 73% sensitivity and 81% specificity; the odds ratio was 11.5 (P = .001) for the differentiation capacity of CPT between MND II and III, with a cutoff of 11. The area under the receiver-operating-characteristic curve was 0.84 (95% confidence interval: 0.72, 0.96; P<.001). CPT testing has moderate discriminatory accuracy, specificity, and sensitivity for classification of MND categories into neck pain with or without neurological signs. J Orthop Sports Phys Ther 2014;44(7):532-540. Epub 10 May 2014

Measurement invariance within and between individuals: a distinct problem in testing the equivalence of intra- and inter-individual model structures.

Science.gov (United States)

Adolf, Janne; Schuurman, Noémi K; Borkenau, Peter; Borsboom, Denny; Dolan, Conor V

2014-01-01

We address the question of equivalence between modeling results obtained on intra-individual and inter-individual levels of psychometric analysis. Our focus is on the concept of measurement invariance and the role it may play in this context. We discuss this in general against the background of the latent variable paradigm, complemented by an operational demonstration in terms of a linear state-space model, i.e., a time series model with latent variables. Implemented in a multiple-occasion and multiple-subject setting, the model simultaneously accounts for intra-individual and inter-individual differences. We consider the conditions-in terms of invariance constraints-under which modeling results are generalizable (a) over time within subjects, (b) over subjects within occasions, and (c) over time and subjects simultaneously thus implying an equivalence-relationship between both dimensions. Since we distinguish the measurement model from the structural model governing relations between the latent variables of interest, we decompose the invariance constraints into those that involve structural parameters and those that involve measurement parameters and relate to measurement invariance. Within the resulting taxonomy of models, we show that, under the condition of measurement invariance over time and subjects, there exists a form of structural equivalence between levels of analysis that is distinct from full structural equivalence, i.e., ergodicity. We demonstrate how measurement invariance between and within subjects can be tested in the context of high-frequency repeated measures in personality research. Finally, we relate problems of measurement variance to problems of non-ergodicity as currently discussed and approached in the literature.

The utility of a continuous performance test embedded in virtual reality in measuring ADHD-related deficits.

Science.gov (United States)

Pollak, Yehuda; Weiss, Patricia L; Rizzo, Albert A; Weizer, Merav; Shriki, Liron; Shalev, Ruth S; Gross-Tsur, Varda

2009-02-01

Continuous performance tasks (CPT) are popular in the diagnostic process of Attention Deficit/Hyperactivity Disorder (ADHD), providing an objective measure of attention for a disorder with otherwise subjective criteria. Aims of the study were to: (1) compare the performance of children with ADHD on a CPT embedded within a virtual reality classroom (VR-CPT) to the currently used Test of Variables of Attention (TOVA) CPT, and (2) assess how the VR environment is experienced. Thirty-seven boys, 9 to 17 years, with (n = 20) and without ADHD (n = 17) underwent 3 CPT's: VR-CPT, the same CPT without VR (No VR-CPT) and the TOVA. Immediately following CPT, subjects described their subjective experiences on the Short Feedback Questionnaire. Results were analyzed using analysis of variance with repeated measures. Children with ADHD performed poorer on all CPT's. The VR-CPT showed similar effect sizes to the TOVA. Subjective feelings of enjoyment were most positive for VR-CPT. The VR-CPT is a sensitive and user-friendly assessment tool to aid diagnosis in ADHD.

Analytical study on U/G coal mine CPT and inferences

Energy Technology Data Exchange (ETDEWEB)

Dey, N.C.; Mukhopadhyay, S. [Bengal Engineering College, Howrath (India). Dept. of Mining and Geology

1999-08-01

The analytical aspects of underground CPT (coal mine cost per tonne), which varies from mine to mine due to the different weightages of various contributing factors, are described. The CPT is not only dictated by the increasing wages but also by the availability of man-hour and accountability of machine utilization. An optimal blend of labour-intensive and machine-intensive methods involving least investment and operating cost, is a challenge for the coal industry. Technology upgradation and implementation, higher skill and morale, excellence in planning and monitoring, optimization in capacity utilization, and better consumer acceptability of coal will consistently improve the financial health of the coal mining sector. Other factors which will help improve the financial health of coal mining industries are (1) cost propaganda like safety week celebration; (2) cost consciousness at all levels; (3) noticeboard comprising the cost of man-hour and machine- hour; (4) no idle time for men as well as machine; (5) care to increase the life of machines; (6) scope of target amendment in a year; (7) prior to introducing costly machines, due weightage to be given on coal grade, mine life, geo-mining conditions; and (8) award to most economic mine and punishment to others rated below the BEP (break- even point). 2 refs., 3 figs.

Testing strong factorial invariance using three-level structural equation modeling

NARCIS (Netherlands)

Jak, Suzanne

Within structural equation modeling, the most prevalent model to investigate measurement bias is the multigroup model. Equal factor loadings and intercepts across groups in a multigroup model represent strong factorial invariance (absence of measurement bias) across groups. Although this approach is

Proposed experiment addressing CP and CPT violation in the K0-K-bar0 system

International Nuclear Information System (INIS)

Dunietz, I.; Hauser, J.; Rosner, J.L.

1987-01-01

An experiment utilizing the decay phi→K/sub S/K/sub L/ is proposed for measuring the ratio ε'/ε of CP-violating parameters in the kaon system. It appears one can probe values of ε'/ε down to 10/sup -3/ with 10 9 phi's. An asymmetry measurement of the relative times of π + π - and π 0 π 0 decays is capable of testing the phase difference phi/sub +-/-phi/sub 00/ to +- 1.6 0 (3σ), with 10/sup 10/ phi's. Far fewer phi's (perhaps 10 8 ) can be useful in constraining some parameters of the kaon system associated with CPT violations

Geotechnical Site Assessment by Seismic Piezocone Test in North of Denmark

DEFF Research Database (Denmark)

Firouzianbandpey, Sarah; Andersen, Lars Vabbersgaard; Nielsen, Benjaminn Nordahl

2013-01-01

These days cone penetration tests (CPT) have gained more popularity as an alternative to the conventional laboratory tests for subsurface investigation and estimation of soil parameters. Due to increasing interest in soil dynamics in the last decades, there is a development of CPT as a seismic pi...

Dimensionality and measurement invariance in the Satisfaction with Life Scale in Norway.

Science.gov (United States)

Clench-Aas, Jocelyne; Nes, Ragnhild Bang; Dalgard, Odd Steffen; Aarø, Leif Edvard

2011-10-01

Results from previous studies examining the dimensionality and factorial invariance of the Satisfaction with Life Scale (SWLS) are inconsistent and often based on small samples. This study examines the factorial structure and factorial invariance of the SWLS in a Norwegian sample. Confirmatory factor analysis (AMOS) was conducted to explore dimensionality and test for measurement invariance in factor structure, factor loadings, intercepts, and residual variance across gender and four age groups in a large (N = 4,984), nationally representative sample of Norwegian men and women (15-79 years). The data supported a modified unidimensional structure. Factor loadings could be constrained to equality between the sexes, indicating metric invariance between genders. Further testing indicated invariance also at the strong and strict levels, thus allowing analyses involving group means. The SWLS was shown to be sensitive to age, however, at the strong and strict levels of invariance testing. In conclusion, the results in this Norwegian study seem to confirm that a unidimensional structure is acceptable, but that a modified single-factor model with correlations between error terms of items 4 and 5 is preferred. Additionally, comparisons may be made between the genders. Caution must be exerted when comparing age groups.

Translation, Adaptation and Invariance Testing of the Teaching Perspectives Inventory: Comparing Faculty of Malaysia and the United States

Science.gov (United States)

Misieng, Jecky

2013-01-01

As a result of growing attention in cross-cultural research, existing measurement instruments developed in one language are being translated and adapted for use in other languages and cultural contexts. Producing invariant measurement instruments that assess educational and psychological constructs provide a way of testing the cross-cultural…

AULA virtual reality test as an attention measure: convergent validity with Conners' Continuous Performance Test.

Science.gov (United States)

Díaz-Orueta, Unai; Garcia-López, Cristina; Crespo-Eguílaz, Nerea; Sánchez-Carpintero, Rocío; Climent, Gema; Narbona, Juan

2014-01-01

The majority of neuropsychological tests used to evaluate attention processes in children lack ecological validity. The AULA Nesplora (AULA) is a continuous performance test, developed in a virtual setting, very similar to a school classroom. The aim of the present study is to analyze the convergent validity between the AULA and the Continuous Performance Test (CPT) of Conners. The AULA and CPT were administered correlatively to 57 children, aged 6-16 years (26.3% female) with average cognitive ability (IQ mean = 100.56, SD = 10.38) who had a diagnosis of attention deficit/hyperactivity disorder (ADHD) according to DSM-IV-TR criteria. Spearman correlations analyses were conducted among the different variables. Significant correlations were observed between both tests in all the analyzed variables (omissions, commissions, reaction time, and variability of reaction time), including for those measures of the AULA based on different sensorial modalities, presentation of distractors, and task paradigms. Hence, convergent validity between both tests was confirmed. Moreover, the AULA showed differences by gender and correlation to Perceptual Reasoning and Working Memory indexes of the WISC-IV, supporting the relevance of IQ measures in the understanding of cognitive performance in ADHD. In addition, the AULA (but not Conners' CPT) was able to differentiate between ADHD children with and without pharmacological treatment for a wide range of measures related to inattention, impulsivity, processing speed, motor activity, and quality of attention focus. Additional measures and advantages of the AULA versus Conners' CPT are discussed.

CPT-conserving hamiltonians and their nonlinear supersymmetrization using differential charge-operators C

Czech Academy of Sciences Publication Activity Database

Bagchi, B.; Quesne, C.; Znojil, Miloslav; Banerjee, A.; Geyer, HB; Caliceti, E.; Cannata, F.

2005-01-01

Roč. 20, č. 30 (2005), s. 7107-7128 ISSN 0217-751X R&D Projects: GA AV ČR IAA1048302 Institutional research plan: CEZ:AV0Z10480505 Keywords : PT-symmetric Hamiltonians * CPT-symmetric quantum-mechanics * supersymmetric quantum mechanics Subject RIV: BE - Theoretical Physics Impact factor: 1.472, year: 2005

Invariant and Absolute Invariant Means of Double Sequences

Directory of Open Access Journals (Sweden)

Abdullah Alotaibi

2012-01-01

Full Text Available We examine some properties of the invariant mean, define the concepts of strong σ-convergence and absolute σ-convergence for double sequences, and determine the associated sublinear functionals. We also define the absolute invariant mean through which the space of absolutely σ-convergent double sequences is characterized.

Nonlinear Lorentz-invariant theory of gravitation

International Nuclear Information System (INIS)

Petry, W.

1976-01-01

A nonlinear Lorentz-invariant theory of gravitation and a Lorentz-invariant Hamiltonian for a particle with spin in the gravitational field are developed. The equations of motions are studied. The theory is applied to the three well known tests of General Relativity. In the special case of the red shift of spectral lines and of the deflection of light, the theory gives the same results as the General Theory of Relativity, whereas in the case of the perihelion of the Mercury, the theory gives 40,3'', in good agreement with experimental results of Dicke. (author)

Jet invariant mass in quantum chromodynamics

International Nuclear Information System (INIS)

Clavelli, L.

1979-03-01

We give heuristic argument that a new class of observable related to the invariant mass of jets in e + e - annihilation is infrared finite to all orders of perturbation theory in Quantum Chromodynamics. We calculate the lowest order QCD predictions for the mass distribution as well as for the double differential cross section to produce back to back jets of invariant mass M 1 and M 2 . The resulting cross sections are quite different from that expected in simple hadronic fireball models and should provide experimentally accessible tests of QCD. (orig.) [de

On the duality in CPT-even Lorentz-breaking theories

Energy Technology Data Exchange (ETDEWEB)

Scarpelli, A.P.B. [Departamento de Policia Federal, Sao Paulo (Brazil); Ribeiro, R.F.; Nascimento, J.R.; Petrov, A.Yu. [Universidade Federal da Paraiba, Departamento de Fisica (Brazil)

2015-07-15

We generalize the duality between self-dual and Maxwell-Chern-Simons theories for the case of a CPT-even Lorentz-breaking extension of these theories. The duality is shown using the gauge embedding procedure, both in free and coupled cases, and with the master action approach. The physical spectra of both Lorentz-breaking theories are studied. The massive poles are shown to coincide and to respect the requirements for unitarity and causality at tree level. The extra massless poles which are present in the dualized model are shown to be nondynamical. (orig.)

On the duality in CPT-even Lorentz-breaking theories

International Nuclear Information System (INIS)

Scarpelli, A.P.B.; Ribeiro, R.F.; Nascimento, J.R.; Petrov, A.Yu.

2015-01-01

We generalize the duality between self-dual and Maxwell-Chern-Simons theories for the case of a CPT-even Lorentz-breaking extension of these theories. The duality is shown using the gauge embedding procedure, both in free and coupled cases, and with the master action approach. The physical spectra of both Lorentz-breaking theories are studied. The massive poles are shown to coincide and to respect the requirements for unitarity and causality at tree level. The extra massless poles which are present in the dualized model are shown to be nondynamical. (orig.)

Measurement Invariance: A Foundational Principle for Quantitative Theory Building

Science.gov (United States)

Nimon, Kim; Reio, Thomas G., Jr.

2011-01-01

This article describes why measurement invariance is a critical issue to quantitative theory building within the field of human resource development. Readers will learn what measurement invariance is and how to test for its presence using techniques that are accessible to applied researchers. Using data from a LibQUAL+[TM] study of user…

[Vestibular testing abnormalities in individuals with motion sickness].

Science.gov (United States)

Ma, Yan; Ou, Yongkang; Chen, Ling; Zheng, Yiqing

2009-08-01

To evaluate the vestibular function of motion sickness. VNG, which tests the vestibular function of horizontal semicircular canal, and CPT, which tests vestibulospinal reflex and judge proprioceptive, visual and vestibular status, were performed in 30 motion sickness patients and 20 healthy volunteers (control group). Graybiel score was recorded at the same time. Two groups' Graybiel score (12.67 +/- 11.78 vs 2.10 +/- 6.23; rank test P<0.05), caloric test labyrinth value [(19.02 +/- 8.59) degrees/s vs (13.58 +/- 5.25) degrees/s; t test P<0.05], caloric test labyrinth value of three patients in motion sickness group exceeded 75 degrees/s. In computerized posturography testing (CPT), motion sickness patients were central type (66.7%) and disperse type (23.3%); all of control group were central type. There was statistical significance in two groups' CTP area, and motion sickness group was obviously higher than control group. While stimulating vestibulum in CPT, there was abnormality (35%-50%) in motion sickness group and none in control group. Generally evaluating CPT, there was only 2 proprioceptive hypofunction, 3 visual hypofunction, and no vestibular hypofunction, but none hypofunction in control group. Motion sickness patients have high vestibular susceptible, some with vestibular hyperfunction. In posturography, a large number of motion sickness patients are central type but no vestibular hypofunction, but it is hard to keep balance when stimulating vestibulum.

The signal of ill-defined CPT weakening entanglement in the B{sub d} system

Energy Technology Data Exchange (ETDEWEB)

Bernabeu, Jose; Botella, Francisco J. [Valencia Univ.-CSIC, Burjassot (Spain). Dept. de Fisica Teorica, IFIC; Mavromatos, Nick E. [Valencia Univ.-CSIC, Burjassot (Spain). Dept. de Fisica Teorica, IFIC; King' s College London (United Kingdom). Theoretical Particle Physics and Cosmology Group; Nebot, Miguel [Lisboa Univ. (Portugal). Centro de Fisica Teorica de Particulas (CFTP)

2017-12-15

In the presence of quantum-gravity fluctuations (space-time foam), the CPT operator may be ill-defined. Its perturbative treatment leads to a modification of the Einstein-Podolsky-Rosen correlation of the neutral meson system by adding an entanglement-weakening term of the wrong exchange symmetry, the ω-effect. In the current paper we identify how to probe the complex ω in the entangled B{sub d}-system using the flavour (f)-CP(g) eigenstate decay channels: the connection between the intensities for the two time-ordered decays (f, g) and (g, f) is lost. Appropriate observables are constructed allowing independent experimental determinations of Re(ω) and Im(ω), disentangled from CPT violation in the evolution Hamiltonian Re(θ) and Im(θ). 2σ tensions for both Re(θ) and Im(ω) are shown to be uncorrelated. (orig.)

Invariant and semi-invariant probabilistic normed spaces

Energy Technology Data Exchange (ETDEWEB)

Ghaemi, M.B. [School of Mathematics Iran, University of Science and Technology, Narmak, Tehran (Iran, Islamic Republic of)], E-mail: mghaemi@iust.ac.ir; Lafuerza-Guillen, B. [Departamento de Estadistica y Matematica Aplicada, Universidad de Almeria, Almeria E-04120 (Spain)], E-mail: blafuerz@ual.es; Saiedinezhad, S. [School of Mathematics Iran, University of Science and Technology, Narmak, Tehran (Iran, Islamic Republic of)], E-mail: ssaiedinezhad@yahoo.com

2009-10-15

Probabilistic metric spaces were introduced by Karl Menger. Alsina, Schweizer and Sklar gave a general definition of probabilistic normed space based on the definition of Menger . We introduce the concept of semi-invariance among the PN spaces. In this paper we will find a sufficient condition for some PN spaces to be semi-invariant. We will show that PN spaces are normal spaces. Urysohn's lemma, and Tietze extension theorem for them are proved.

Carnitine palmitoyltransferase 1A (CPT1A): a transcriptional target of PAX3-FKHR and mediates PAX3-FKHR–dependent motility in alveolar rhabdomyosarcoma cells

International Nuclear Information System (INIS)

Liu, Lingling; Wang, Yong-Dong; Wu, Jing; Cui, Jimmy; Chen, Taosheng

2012-01-01

Alveolar rhabdomyosarcoma (ARMS) has a high propensity to metastasize, leading to its aggressiveness and a poor survival rate among those with the disease. More than 80% of aggressive ARMSs harbor a PAX3-FKHR fusion transcription factor, which regulates cell migration and promotes metastasis, most likely by regulating the fusion protein’s transcriptional targets. Therefore, identifying druggable transcription targets of PAX3-FKHR that are also downstream effectors of PAX3-FKHR–mediated cell migration and metastasis may lead to novel therapeutic approaches for treating ARMS. To identify genes whose expression is directly affected by the level of PAX3-FKHR in an ARMS cellular-context, we first developed an ARMS cell line in which PAX3-FKHR is stably down-regulated, and showed that stably downregulating PAX3-FKHR in ARMS cells significantly decreased the cells’ motility. We used microarray analysis to identify genes whose expression level decreased when PAX3-FKHR was downregulated. We used mutational analysis, promoter reporter assays, and electrophoretic mobility shift assays to determine whether PAX3-FKHR binds to the promoter region of the target gene. We used siRNA and pharmacologic inhibitor to downregulate the target gene of PAX3-FKHR and investigated the effect of such downregulation on cell motility. We found that when PAX3-FKHR was downregulated, the expression of carnitine palmitoyltransferase 1A (CPT1A) decreased. We showed that PAX3-FKHR binds to a paired-domain binding-site in the CPT1A promoter region, indicating that CPT1A is a novel transcriptional target of PAX3-FKHR. Furthermore, downregulating CPT1A decreased cell motility in ARMS cells, indicating that CPT1A is a downstream effector of PAX3-FKHR–mediated cell migration and metastasis. Taken together, we have identified CPT1A as a novel transcriptional target of PAX3-FKHR and revealed the novel function of CPT1A in promoting cell motility. CPT1A may represent a novel therapeutic target for

Videogame e sua influência em teste de atenção Videojuegos y su influencia en la atención Videogame impact in attention test

Directory of Open Access Journals (Sweden)

Luciana Alves

2010-09-01

Full Text Available Esta pesquisa objetivou investigar a performance em cinco variáveis do Continuous Performance Test (CPT-II, um teste de atenção sustentada. Dela participaram 30 indivíduos, com idades entre 10 e 16 anos, envolvidos nas atividades de uma organização não governamental (ONG para crianças carentes, organizados em dois grupos: um grupo de jogadores de videogame (JVGs e um de não jogadores de videogame (NJVGs. Todos eles foram testados no CPT-II e o grupo de NJVGs foi treinado por 20 sessões em dois jogos de videogame. Os NJVGs foram retestados no CPT-II. Verificou-se que, inicialmente, o grupo de JVGs apresentou um desempenho melhor do que o grupo de NJVGs. Após a intervenção experimental constatou-se que este último grupo apresentou uma melhor performance nas variáveis avaliadas do teste. Os resultados mostraram que o regime de treinamento e os jogos de videogame utilizados foram eficientes para melhorar o desempenho de adolescentes NJVGs no CPT II.Este estudio tuvo como objetivo investigar la actuación de cinco variables en Continuous Performance Test (CPT-II, una prueba de atención sostenida. Participaron 30 individuos con edades entre 10 y 16 anos, envueltos en las actividades de una Organización no Gubernamental (ONG para niños carentes, organizados en dos grupos: uno para los jugadores de videojuegos (JV y otros con no jugadores de videojuegos (NJV. Todos se pusieron a prueba en el CPT-II y el grupo de NJV se formó por 20 sesiones en dos videojuegos. El NJV fueron re-probado en la CPT-II. Se encontró que en principio, el grupo JV mostraron mejor rendimiento que el grupo de NJV. Después de la intervención ensayo encontró que este último grupo mostró un mejor desempeño en las variables de la prueba. Los resultados mostraron que el sistema de formación y los videojuegos utilizados son eficaces para mejorar el rendimiento de los adolescentes NJV en CPT II.The present research aimed to investigate the performance in five

Environmental CPT Violation in an Expanding Universe in String Theory

CERN Document Server

Ellis, John; Sarkar, Sarben

2013-01-01

We consider a model of an expanding Universe in string theory that yields `environmental' CPT violation for fermions, in the sense of different dispersion relations for fermions and antifermions. These are induced by a cosmological background with constant torsion provided by the Kalb-Ramond antisymmetric tensor field (axion) of the string gravitational multiplet. This effect induces different densities of neutrinos and antineutrinos while in chemical equilibrium, offering new scenarios for leptogenesis and baryogenesis even in the absence of CP violation.

Measurement Invariance of the "Servant Leadership Questionnaire" across K-12 Principal Gender

Science.gov (United States)

Xu, Lihua; Stewart, Trae; Haber-Curran, Paige

2015-01-01

Measurement invariance of the five-factor "Servant Leadership Questionnaire" between female and male K-12 principals was tested using multi-group confirmatory factor analysis. A sample of 956 principals (56.9% were females and 43.1% were males) was analysed in this study. The hierarchical multi-step measurement invariance test supported…

Rotationally invariant correlation filtering

International Nuclear Information System (INIS)

Schils, G.F.; Sweeney, D.W.

1985-01-01

A method is presented for analyzing and designing optical correlation filters that have tailored rotational invariance properties. The concept of a correlation of an image with a rotation of itself is introduced. A unified theory of rotation-invariant filtering is then formulated. The unified approach describes matched filters (with no rotation invariance) and circular-harmonic filters (with full rotation invariance) as special cases. The continuum of intermediate cases is described in terms of a cyclic convolution operation over angle. The angular filtering approach allows an exact choice for the continuous trade-off between loss of the correlation energy (or specificity regarding the image) and the amount of rotational invariance desired

Properties of invariant modelling and invariant glueing of vector fields

International Nuclear Information System (INIS)

Petukhov, V.R.

1987-01-01

Invariant modelling and invariant glueing of both continuous (rates and accelerations) and descrete vector fields, gradient and divergence cases are considered. The following appendices are discussed: vector fields in crystals, crystal disclinations, topological charges and their fields

Tomographic site characterization using CPT, ERT, and GPR. Innovative Technology Summary Report

International Nuclear Information System (INIS)

None

2000-01-01

ARA developed a geophysical tomographic system that incorporates results from Electrical Resistivity Tomography (ERT) measurements and Ground Penetrating Radar (GPR) Tomography measurements. Both methods are useful for imaging subsurface structures and processes, however, GPR is more effective in sandy material and ERT is more effective in clayey material. CPT or drilling is used to deploy the electrodes in the subsurface

A precision test of Lorentz invariance using room-temperature high-finesse optical resonators

International Nuclear Information System (INIS)

Eisele, Christian

2009-01-01

An apparatus for a test of a basic postulate of the theory of Special Relativity, the isotropy of the speed of light, has been developed. Deviations from the isotropy imply a violation of Lorentz invariance, a symmetry assumed by all established theories of the fundamental forces. Such a signal may provide a glimpse on physics beyond our current theories of the fundamental forces, the General Theory of Relativity and the Standard Modell of particle physics. Since long theoreticians try to unify General Relativity and the Standard Modell within one theory, a grand unified theory (GUT). So far they did not succeed, although promising candidate theories have been developed, e.g. string theories or loop quantum gravity. However, there are hints that Lorentz invariance might not be an exact symmetry of nature, but that deviations are to be expected. This is a strong motivation for tests of Lorentz invariance with increased sensitivity as the one presented within this thesis. We employ, for the first time for a test of the isotropy of the speed of light, monolithic optical resonators fabricated from a glass ceramic with ultra low expansion coefficient (ULE). By means of a monolithic Nd:YAG-laser (λ = 1064 nm) we measure the difference between the resonance frequencies of two orthogonally oriented resonators. The low thermal expansion coefficient reduces the influence of thermal fluctuations on the resonance frequencies, which are a function of the mirror spacing and the speed of light inside the resonators only. The complete optical setup has been put on top of active vibration isolation supports, which strongly damp mechanical vibrations. This improves the short-time stability of the resonators resonance frequencies. This technique is used for the first time in a Speed of Light Isotropy Test (SLIT) experiment. Furthermore, a system for the stabilization of the tilt of the optics breadboard is implemented, based on electromagnetic actuators. This stabilization is

A precision test of Lorentz invariance using room-temperature high-finesse optical resonators

Energy Technology Data Exchange (ETDEWEB)

Eisele, Christian

2009-10-28

An apparatus for a test of a basic postulate of the theory of Special Relativity, the isotropy of the speed of light, has been developed. Deviations from the isotropy imply a violation of Lorentz invariance, a symmetry assumed by all established theories of the fundamental forces. Such a signal may provide a glimpse on physics beyond our current theories of the fundamental forces, the General Theory of Relativity and the Standard Modell of particle physics. Since long theoreticians try to unify General Relativity and the Standard Modell within one theory, a grand unified theory (GUT). So far they did not succeed, although promising candidate theories have been developed, e.g. string theories or loop quantum gravity. However, there are hints that Lorentz invariance might not be an exact symmetry of nature, but that deviations are to be expected. This is a strong motivation for tests of Lorentz invariance with increased sensitivity as the one presented within this thesis. We employ, for the first time for a test of the isotropy of the speed of light, monolithic optical resonators fabricated from a glass ceramic with ultra low expansion coefficient (ULE). By means of a monolithic Nd:YAG-laser ({lambda} = 1064 nm) we measure the difference between the resonance frequencies of two orthogonally oriented resonators. The low thermal expansion coefficient reduces the influence of thermal fluctuations on the resonance frequencies, which are a function of the mirror spacing and the speed of light inside the resonators only. The complete optical setup has been put on top of active vibration isolation supports, which strongly damp mechanical vibrations. This improves the short-time stability of the resonators resonance frequencies. This technique is used for the first time in a Speed of Light Isotropy Test (SLIT) experiment. Furthermore, a system for the stabilization of the tilt of the optics breadboard is implemented, based on electromagnetic actuators. This stabilization is

Evaluation of SPT energy for Donut and Safety hammers using CPT measurements in Egypt

Directory of Open Access Journals (Sweden)

Rami M. El-Sherbiny

2013-12-01

Full Text Available Standard Penetration Test (SPT blow counts require correction prior to utilization in soil characterization and determination of properties and behavior. Among the most important corrections is the energy correction required to adjust the blow counts to 60% energy efficiency. However, there are no published data supporting commonly used value in Egypt. This paper presents an evaluation of the energy efficiency of the Donut and Safety hammers commonly used in Egypt and the associated energy correction factor. The energy efficiency is estimated by comparing N-values from the SPT to back-calculated N60 values from the Cone Penetration Test (CPT using well established correlations. Results indicate that the energy efficiency of the Donut hammer based on current practice in Egypt is approximately 50%. Thus, the back-calculated energy correction factor is approximately 0.82. For the Safety hammer, results indicate that the energy efficiency is approximately 60%, and the energy correction factor is approximately 1.0.

What are the anti-particles of KL,S

International Nuclear Information System (INIS)

Mathur, V.S.; Rajeev, S.G.

1991-01-01

The authors study the consequences of an anti-unitary symmetry such as CPT for an unstable quantum system described by a non-self-adjoint Hamiltonian. In this paper it is shown that CPT invariance by itself does not imply that every particle has an anti-particle of equal mass and life-time. In particular, the neutral kaons K L and K S do not have anti-particles even when CPT is conserved

Invariance algorithms for processing NDE signals

Science.gov (United States)

Mandayam, Shreekanth; Udpa, Lalita; Udpa, Satish S.; Lord, William

1996-11-01

Signals that are obtained in a variety of nondestructive evaluation (NDE) processes capture information not only about the characteristics of the flaw, but also reflect variations in the specimen's material properties. Such signal changes may be viewed as anomalies that could obscure defect related information. An example of this situation occurs during in-line inspection of gas transmission pipelines. The magnetic flux leakage (MFL) method is used to conduct noninvasive measurements of the integrity of the pipe-wall. The MFL signals contain information both about the permeability of the pipe-wall and the dimensions of the flaw. Similar operational effects can be found in other NDE processes. This paper presents algorithms to render NDE signals invariant to selected test parameters, while retaining defect related information. Wavelet transform based neural network techniques are employed to develop the invariance algorithms. The invariance transformation is shown to be a necessary pre-processing step for subsequent defect characterization and visualization schemes. Results demonstrating the successful application of the method are presented.

Contribution of CPLEAR to the physics of the neutral-kaon system

International Nuclear Information System (INIS)

Angelopoulos, A.; Apostolakis, A.; Aslanides, E.; Backenstoss, G.; Bargassa, P.; Behnke, O.; Benelli, A.; Bertin, V.; Blanc, F.; Bloch, P.; Carlson, P.; Carroll, M.; Cawley, E.; Chertok, M.B.; Danielsson, M.; Dejardin, M.; Derre, J.; Ealet, A.; Eleftheriadis, C.A.; Faravel, L.; Fetscher, W.; Fidecaro, M.; Filipcic, A.; Francis, D.; Fry, J.; Gabathuler, E.; Gamet, R.; Gerber, H.-J.; Go, A.; Haselden, A.; Hayman, P.J.; Henry-Couannier, F.; Hollander, R.W.; Jon-And, K.; Kettle, P.-R.; Kokkas, P.; Kreuger, R.; Le Gac, R.; Leimgruber, F.; Mandic, I.; Manthos, N.; Marel, G.; Mikuz, M.; Miller, J.; Montanet, F.; Muller, A.; Nakada, T.; Pagels, B.; Papadopoulos, I.; Pavlopoulos, P.; Polivka, G.; Rickenbach, R.; Roberts, B.L.; Ruf, T.; Schaefer, M.; Schaller, L.A.; Schietinger, T.; Schopper, A.; Schune, P.; Tauscher, L.; Thibault, C.; Touchard, F.; Touramanis, C.; Van Eijk, C.W.E.; Vlachos, S.; Weber, P.; Wigger, O.; Wolter, M.; Zavrtanik, D.; Zimmerman, D.

1999-01-01

We report the results of the CPLEAR experiment on CP-, T- and CPT-symmetries in the neutral kaon system. CP-violation parameters are given for different decay channels. For the first time T-violation is measured by a direct method using semileptonic decays. The CPT symmetry in the kaons decays is tested through the parameters Im(δ), from the Bell-Steinberger relation, with a precision of 10 -5 and Re(δ) with a precision of a few 10 -4 (two order of magnitude better than the previous measurement). These two measurements allow us to bound the difference in mass and width of K 0 and K-bar 0 to be equal within 10 -18 GeV. In the limit of CPT invariance in the neutral kaon decays, the K 0 and K-bar 0 masses are equal within 10 -19 GeV

Reverse translated and gold standard continuous performance tests predict global cognitive performance in schizophrenia.

Science.gov (United States)

Bismark, Andrew W; Thomas, Michael L; Tarasenko, Melissa; Shiluk, Alexandra L; Rackelmann, Sonia Y; Young, Jared W; Light, Gregory A

2018-04-12

Attentional dysfunction contributes to functional impairments in schizophrenia (SZ). Sustained attention is typically assessed via continuous performance tasks (CPTs), though many CPTs have limited cross-species translational validity and place demands on additional cognitive domains. A reverse-translated 5-Choice Continuous Performance Task (5C-CPT) for human testing-originally developed for use in rodents-was designed to minimize demands on perceptual, visual learning, processing speed, or working memory functions. To-date, no studies have validated the 5C-CPT against gold standard attentional measures nor evaluated how 5C-CPT scores relate to cognition in SZ. Here we examined the relationship between the 5C-CPT and the CPT-Identical Pairs (CPT-IP), an established and psychometrically robust measure of vigilance from the MATRICS Consensus Cognitive Battery (MCCB) in a sample of SZ patients (n = 35). Relationships to global and individual subdomains of cognition were also assessed. 5C-CPT and CPT-IP measures of performance (d-prime) were strongly correlated (r = 0.60). In a regression model, the 5C-CPT and CPT-IP collectively accounted for 54% of the total variance in MCCB total scores, and 27.6% of overall cognitive variance was shared between the 5C-CPT and CPT-IP. These results indicate that the reverse translated 5C-CPT and the gold standard CPT-IP index a common attentional construct that also significantly overlaps with variance in general cognitive performance. The use of simple, cross-species validated behavioral indices of attentional/cognitive functioning such as the 5C-CPT could accelerate the development of novel generalized pro-cognitive therapeutics for SZ and related neuropsychiatric disorders.

Reynolds averaged turbulence modelling using deep neural networks with embedded invariance

International Nuclear Information System (INIS)

Ling, Julia; Kurzawski, Andrew; Templeton, Jeremy

2016-01-01

There exists significant demand for improved Reynolds-averaged Navier–Stokes (RANS) turbulence models that are informed by and can represent a richer set of turbulence physics. This paper presents a method of using deep neural networks to learn a model for the Reynolds stress anisotropy tensor from high-fidelity simulation data. A novel neural network architecture is proposed which uses a multiplicative layer with an invariant tensor basis to embed Galilean invariance into the predicted anisotropy tensor. It is demonstrated that this neural network architecture provides improved prediction accuracy compared with a generic neural network architecture that does not embed this invariance property. Furthermore, the Reynolds stress anisotropy predictions of this invariant neural network are propagated through to the velocity field for two test cases. For both test cases, significant improvement versus baseline RANS linear eddy viscosity and nonlinear eddy viscosity models is demonstrated.

Remarks on the E-invariant and the Casson invariant

International Nuclear Information System (INIS)

Seade, J.

1991-08-01

In this work a framed manifold means a pair (M,F) consisting of a closed C ∞ , stably parallelizable manifold M, together with a trivialization F of its stable tangent bundle. The purpose of this work is to understand and determine in higher dimensions the invariant h(M,F) appearing in connection with the Adams e-invariants. 28 refs

Invariants of generalized Lie algebras

International Nuclear Information System (INIS)

Agrawala, V.K.

1981-01-01

Invariants and invariant multilinear forms are defined for generalized Lie algebras with arbitrary grading and commutation factor. Explicit constructions of invariants and vector operators are given by contracting invariant forms with basic elements of the generalized Lie algebra. The use of the matrix of a linear map between graded vector spaces is emphasized. With the help of this matrix, the concept of graded trace of a linear operator is introduced, which is a rich source of multilinear forms of degree zero. To illustrate the use of invariants, a characteristic identity similar to that of Green is derived and a few Racah coefficients are evaluated in terms of invariants

On density of the Vassiliev invariants

DEFF Research Database (Denmark)

Røgen, Peter

1999-01-01

The main result is that the Vassiliev invariants are dense in the set of numeric knot invariants if and only if they separate knots.Keywords: Knots, Vassiliev invariants, separation, density, torus knots......The main result is that the Vassiliev invariants are dense in the set of numeric knot invariants if and only if they separate knots.Keywords: Knots, Vassiliev invariants, separation, density, torus knots...

Traveling solitons in Lorentz and CPT breaking systems

International Nuclear Information System (INIS)

Souza Dutra, A. de; Correa, R. A. C.

2011-01-01

In this work we present a class of traveling solitons in Lorentz and CPT breaking systems. In the case of Lorentz violating scenarios, as far as we know, only static solitonic configurations were analyzed up to now in the literature. Here it is shown that it is possible to construct some traveling solitons which cannot be mapped into static configurations by means of Lorentz boosts due to explicit breaking. In fact, the traveling solutions cannot be reached from the static ones by using something similar to a Lorentz boost in those cases. Furthermore, in the model studied, a complete set of exact solutions is obtained. The solutions present a critical behavior controlled by the choice of an arbitrary integration constant.

Clinical application of K-CPT on preschool children with attention deficit hyperactivity disorder%持续性操作测验在学龄前儿童注意缺陷多动障碍诊断中应用价值探讨

Institute of Scientific and Technical Information of China (English)

谈晓轶; 池霞; 梁沂; 徐亚琴; 王丽; 周影; 张蕾

2012-01-01

Objective:To explore the clinical application of Conners' kiddie continuous performance test (K-CPT) on diagnosis in preschool children with attention deficit hyperactivity (ADHD). Methods:Using the diagnostic and statistical manual of Mental disorders (DSM-IV) as a gold standard, K-CPT and parent symptom questionnaire (PSQ) were tested in 41 cases of preschool children with ADHD and evaluated. Results:Compared with DSM-IV,the sensitivity for K-CPT in diagnosing ADHD reached 73.3%, specificity for K-CPT was 81.8%,the false negative rate was 26.7%,and the false positive rate was 18.2%. The coincidence rate amounted 75.7%. The value of kappa was 0.470 (P 0.05) in the detection rate of K-CPT and PSQ. Discussion:K-CPT could be used as an objective diagnostic tool and applied in diagnosis of preschool ADHD.%目的:探讨4～5岁儿童注意力持续测试软件(Conners' kiddie continuous performance test,K-CPT)在诊断学龄前儿童注意缺陷多动障碍(attention deficit hyperactivity disorder,ADHD)中的临床应用价值.方法:以美国精神障碍诊断和统计手册第4版(DSM-IV)为诊断标准,对41例临床诊断ADHD的儿童,进行Conners'父母用简明症状问卷(parent symptom questionnaire,PSQ)调查和K-CPT评估.结果:K-CPT评估结果与DSM-IV诊断标准比较,在ADHD检出率方面无显著性差异(P＞0.05).K-CPT诊断学龄前ADHD的灵敏度为73.3％,特异度为81.8％,假阳性率为18.2％,假阴性率为26.7％,符合率为75.7％,Kappa值为0.470 (P＜ 0.001),K-CPT与金标准之间存在中度一致性.K-CPT和PSQ在患儿阳性检出率方面,差异均无显著性(P＞0.05).结论:K-CPT测试结果可作为客观诊断指标,用于学龄前ADHD的协助诊断.

Test of parity and time reversal invariance with low energy polarized neutrons

International Nuclear Information System (INIS)

Masaike, Akira

1996-01-01

Measurements of helicity asymmetries in slow neutron reactions on nuclei have been performed by transmission and capture γ-ray detection. Large enhancements of parity-violation effects have been observed on p-wave resonances of various medium and heavy nuclei. The weak matrix elements in hadron reactions have been deduced from these experimental results. Neutron spin precession near the p-wave resonance has been measured. In recent years violation of time reversal invariance is being searched for in the neutron reactions in which large enhancements of the parity violation effects have been observed. The measurement of the term σ n ·(k n x I) in a neutron reaction using polarized neutrons and a polarized target is an example of the test of T-violation. Polarizations of the neutron and lanthanum nucleus for these experiments are also presented. (author)

Acetylcholine versus cold pressor testing for evaluation of coronary endothelial function.

Directory of Open Access Journals (Sweden)

Ahmed AlBadri

Full Text Available Assessment of coronary endothelial function with intracoronary acetylcholine (IC-Ach provides diagnostic and prognostic data in patients with suspected coronary microvascular dysfunction (CMD, but is often not feasible due in part to the time and expertise needed for pharmacologic mixing. Cold pressor testing (CPT is a simple and safe stimulus useful for either invasive or non-invasive endothelial function testing and myocardial perfusion imaging but has not been specifically evaluated among symptomatic women with signs of ischemic heart disease (IHD who have no obstructive coronary artery disease (CAD.163 women with signs and symptoms of IHD and no obstructive CAD from the NHLBI- Women's Ischemia Syndrome Evaluation-Coronary Vascular Dysfunction (WISE-CVD study underwent coronary reactivity testing with a Doppler flow wire (FloWire® Volcano, San Diego, CA in the proximal left anterior descending artery. Coronary artery diameter and coronary blood flow (CBF assessed by core lab using QCA before and after IC-Ach (18.2 μg/ml infused over 3 minutes and during CPT.Mean age was 55 ± 12 years. Rate pressure product (RPP in response to IC-Ach did not change (baseline to peak, P = 0.26, but increased during CPT (363±1457; P = 0.0028. CBF in response to CPT was poorly correlated to IC-Ach CBF. Change in coronary artery diameter after IC-Ach correlated with change after CPT (r = 0.59, P<0.001. The correlation coefficient was stronger in subjects with coronary dilation to IC-Ach (r = 0.628, P<0.001 versus those without dilation (r = 0.353, P = 0.002, suggesting that other factors may be important to this relationship when endothelium is abnormal.In women with no obstructive CAD and suspected CMD, coronary diameter changes with IC-Ach and CPT are moderately-well correlated suggesting that CPT testing may be of some use, particularly among patients with normal endothelial function, however, not an alternative to IC-Ach for diagnosis of coronary

Methylphenidate effect in children with ADHD can be measured by an ecologically valid continuous performance test embedded in virtual reality.

Science.gov (United States)

Pollak, Yehuda; Shomaly, Hanan Barhoum; Weiss, Patrice L; Rizzo, Albert A; Gross-Tsur, Varda

2010-02-01

Continuous performance tasks (CPTs) embedded in a virtual reality (VR) classroom environment have been shown to be a sensitive and user-friendly assessment tool to detect cognitive deficits related to attention-deficit/hyperactivity disorder (ADHD). The aim of the current study was to compare the performance of children with ADHD on a VR-CPT while on and off treatment with methylphenidate (MPH) and to compare the VR-CPT to a currently used CPT, Test of Variables of Attention (TOVA). Twenty-seven children with ADHD underwent the VR-CPT, the same CPT without VR (no VR-CPT), and the TOVA, 1 hour after the ingestion of either placebo or 0.3 mg/kg MPH, in a double-blind, placebo-controlled, crossover design. Immediately following CPT, subjects described their subjective experiences on the Short Feedback Questionnaire. MPH reduced omission errors to a greater extent on the VR-CPT compared to the no VR-CPT and the TOVA, and decreased other CPT measures on all types of CPT to a similar degree. Children rated the VR-CPT as more enjoyable compared to the other types of CPT. It is concluded that the VR-CPT is a sensitive and user-friendly assessment tool in measuring the response to MPH in children with ADHD.

Cohomological invariants in Galois cohomology

CERN Document Server

Garibaldi, Skip; Serre, Jean Pierre

2003-01-01

This volume is concerned with algebraic invariants, such as the Stiefel-Whitney classes of quadratic forms (with values in Galois cohomology mod 2) and the trace form of �tale algebras (with values in the Witt ring). The invariants are analogues for Galois cohomology of the characteristic classes of topology. Historically, one of the first examples of cohomological invariants of the type considered here was the Hasse-Witt invariant of quadratic forms. The first part classifies such invariants in several cases. A principal tool is the notion of versal torsor, which is an analogue of the universal bundle in topology. The second part gives Rost's determination of the invariants of G-torsors with values in H^3(\\mathbb{Q}/\\mathbb{Z}(2)), when G is a semisimple, simply connected, linear group. This part gives detailed proofs of the existence and basic properties of the Rost invariant. This is the first time that most of this material appears in print.

Cosmological disformal invariance

Energy Technology Data Exchange (ETDEWEB)

Domènech, Guillem; Sasaki, Misao [Yukawa Institute for Theoretical Physics, Kyoto University, Kyoto 606-8502 (Japan); Naruko, Atsushi, E-mail: guillem.domenech@yukawa.kyoto-u.ac.jp, E-mail: naruko@th.phys.titech.ac.jp, E-mail: misao@yukawa.kyoto-u.ac.jp [Department of Physics, Tokyo Institute of Technology, 2-12-1 Ookayama, Meguro-ku, Tokyo 152-8551 (Japan)

2015-10-01

The invariance of physical observables under disformal transformations is considered. It is known that conformal transformations leave physical observables invariant. However, whether it is true for disformal transformations is still an open question. In this paper, it is shown that a pure disformal transformation without any conformal factor is equivalent to rescaling the time coordinate. Since this rescaling applies equally to all the physical quantities, physics must be invariant under a disformal transformation, that is, neither causal structure, propagation speed nor any other property of the fields are affected by a disformal transformation itself. This fact is presented at the action level for gravitational and matter fields and it is illustrated with some examples of observable quantities. We also find the physical invariance for cosmological perturbations at linear and high orders in perturbation, extending previous studies. Finally, a comparison with Horndeski and beyond Horndeski theories under a disformal transformation is made.

Donaldson invariants in algebraic geometry

International Nuclear Information System (INIS)

Goettsche, L.

2000-01-01

In these lectures I want to give an introduction to the relation of Donaldson invariants with algebraic geometry: Donaldson invariants are differentiable invariants of smooth compact 4-manifolds X, defined via moduli spaces of anti-self-dual connections. If X is an algebraic surface, then these moduli spaces can for a suitable choice of the metric be identified with moduli spaces of stable vector bundles on X. This can be used to compute Donaldson invariants via methods of algebraic geometry and has led to a lot of activity on moduli spaces of vector bundles and coherent sheaves on algebraic surfaces. We will first recall the definition of the Donaldson invariants via gauge theory. Then we will show the relation between moduli spaces of anti-self-dual connections and moduli spaces of vector bundles on algebraic surfaces, and how this makes it possible to compute Donaldson invariants via algebraic geometry methods. Finally we concentrate on the case that the number b + of positive eigenvalues of the intersection form on the second homology of the 4-manifold is 1. In this case the Donaldson invariants depend on the metric (or in the algebraic geometric case on the polarization) via a system of walls and chambers. We will study the change of the invariants under wall-crossing, and use this in particular to compute the Donaldson invariants of rational algebraic surfaces. (author)

Moment invariants for particle beams

International Nuclear Information System (INIS)

Lysenko, W.P.; Overley, M.S.

1988-01-01

The rms emittance is a certain function of second moments in 2-D phase space. It is preserved for linear uncoupled (1-D) motion. In this paper, the authors present new functions of moments that are invariants for coupled motion. These invariants were computed symbolically using a computer algebra system. Possible applications for these invariants are discussed. Also, approximate moment invariants for nonlinear motion are presented

Lorentz invariance on trial in the weak decay of polarized atoms

Energy Technology Data Exchange (ETDEWEB)

Mueller, Stefan E., E-mail: s.mueller@kvi.nl [Kernfysisch Versneller Instituut (Netherlands)

2013-03-15

One of the most fundamental principles underlying our current understanding of nature is the invariance of the laws of physics under Lorentz transformations. Theories trying to unify the Standard Model with quantum gravity suggest that this invariance may be broken by the presence of Lorentz-violating background fields. Dedicated high-precision experiments at low energies could observe such suppressed signals from the Planck scale. At KVI, a test on Lorentz invariance of the weak interaction is performed searching for a dependence of the decay rate of spin-polarized nuclei on the orientation of their spin with respect to a fixed absolute galactical reference frame. An observation of such a dependence would imply a violation of Lorentz invariance.

Measurement of job motivation in TEDS-M: testing for invariance across countries and cultures

Directory of Open Access Journals (Sweden)

Christin Laschke

2016-09-01

Full Text Available Abstract The paper presents the challenges of cross-country and cross-cultural research on the motivation to become a mathematics teacher based on data from the “Teacher Education and Development Study in Mathematics (TEDS-M”. Referring to studies from cross-cultural psychology, measurement invariance (MI of constructs representing different motivations to become a teacher was examined in confirmatory factor analysis (CFA across the countries that participated in TEDS-M. The data supported metric invariance which means that comparing relationships between motivation and other constructs across countries is permitted, with the exception of extrinsic motivation in Taiwan. Scalar invariance was not supported by the data across countries but across cultures: Scale means can be compared between Germany, Switzerland and (with regard to intrinsic motivation Norway and Poland as well as between Singapore and Taiwan (with regard to the intrinsic motivation and Malaysia, Philippines and Thailand (again regarding intrinsic motivation.

Modal Identification of a Time-Invariant 6-Storey Model Test RC-Frame from Free Decay Tests using Multi-Variate Models

DEFF Research Database (Denmark)

Skjærbæk, P. S.; Nielsen, Søren R. K.; Kirkegaard, Poul Henning

1997-01-01

in the comparison. The data investigated are sampled from a laboratory model of a plane 6-storey, 2-bay RC-frame. The laboratory model is excited at the top storey where two different types of excitation where considered. In the first case the structure was excited in the first mode and in the second case......The scope of the paper is to apply multi-variate time-domain models for identification of eginfrequencies and mode shapes of a time- invariant model test Reinforced Concrete (RC) frame from measured decays. The frequencies and mode shapes of interest are the two lowest ones since they are normally...

Modal Identification of a Time-Invariant 6-Storey Model Test RC-Frame from Free Decay Tests using Multi-Variate Models

DEFF Research Database (Denmark)

Skjærbæk, P. S.; Nielsen, Søren R. K.; Kirkegaard, Poul Henning

in the comparison. The data investigated are sampled from a laboratory model of a plane 6-storey, 2-bay RC-frame. The laboratory model is excited at the top storey where two different types of excitation where considered. In the first case the structure was excited in the first mode and in the second case......The scope of the paper is to apply multi-variate time-domain models for identification of eginfrequencies and mode shapes of a time- invariant model test Reinforced Concrete (RC) frame from measured decays. The frequencies and mode shapes of interest are the two lowest ones since they are normally...

The CPT-theorem in two-dimensional theories of local observables

International Nuclear Information System (INIS)

Borchers, H.J.

1992-01-01

Let M be a von Neumann algebra with cyclic and separating vector Ω, and let U(a) be a continuous unitary representation of R with positive generator and Ω as fixed point. If these unitaries induce for positive arguments endomorphisms of M then the modular group act as dilatations on the group of unitaries. Using this it will be shown that every theory of local observables in two dimensions, which is covariant under translations only, can be imbedded into a theory of local observables covariant under the whole Poincare group. This theory is also covariant under the CPT-transformation. (orig.)

Electrosensory Midbrain Neurons Display Feature Invariant Responses to Natural Communication Stimuli.

Directory of Open Access Journals (Sweden)

Tristan Aumentado-Armstrong

2015-10-01

Full Text Available Neurons that respond selectively but in an invariant manner to a given feature of natural stimuli have been observed across species and systems. Such responses emerge in higher brain areas, thereby suggesting that they occur by integrating afferent input. However, the mechanisms by which such integration occurs are poorly understood. Here we show that midbrain electrosensory neurons can respond selectively and in an invariant manner to heterogeneity in behaviorally relevant stimulus waveforms. Such invariant responses were not seen in hindbrain electrosensory neurons providing afferent input to these midbrain neurons, suggesting that response invariance results from nonlinear integration of such input. To test this hypothesis, we built a model based on the Hodgkin-Huxley formalism that received realistic afferent input. We found that multiple combinations of parameter values could give rise to invariant responses matching those seen experimentally. Our model thus shows that there are multiple solutions towards achieving invariant responses and reveals how subthreshold membrane conductances help promote robust and invariant firing in response to heterogeneous stimulus waveforms associated with behaviorally relevant stimuli. We discuss the implications of our findings for the electrosensory and other systems.

Electrosensory Midbrain Neurons Display Feature Invariant Responses to Natural Communication Stimuli.

Science.gov (United States)

Aumentado-Armstrong, Tristan; Metzen, Michael G; Sproule, Michael K J; Chacron, Maurice J

2015-10-01

Neurons that respond selectively but in an invariant manner to a given feature of natural stimuli have been observed across species and systems. Such responses emerge in higher brain areas, thereby suggesting that they occur by integrating afferent input. However, the mechanisms by which such integration occurs are poorly understood. Here we show that midbrain electrosensory neurons can respond selectively and in an invariant manner to heterogeneity in behaviorally relevant stimulus waveforms. Such invariant responses were not seen in hindbrain electrosensory neurons providing afferent input to these midbrain neurons, suggesting that response invariance results from nonlinear integration of such input. To test this hypothesis, we built a model based on the Hodgkin-Huxley formalism that received realistic afferent input. We found that multiple combinations of parameter values could give rise to invariant responses matching those seen experimentally. Our model thus shows that there are multiple solutions towards achieving invariant responses and reveals how subthreshold membrane conductances help promote robust and invariant firing in response to heterogeneous stimulus waveforms associated with behaviorally relevant stimuli. We discuss the implications of our findings for the electrosensory and other systems.

Relating measurement invariance, cross-level invariance, and multilevel reliability

OpenAIRE

Jak, S.; Jorgensen, T.D.

2017-01-01

Data often have a nested, multilevel structure, for example when data are collected from children in classrooms. This kind of data complicate the evaluation of reliability and measurement invariance, because several properties can be evaluated at both the individual level and the cluster level, as well as across levels. For example, cross-level invariance implies equal factor loadings across levels, which is needed to give latent variables at the two levels a similar interpretation. Reliabili...

Symmetry violating kaon decays

International Nuclear Information System (INIS)

Herczeg, P.

1979-01-01

An analysis of the muon number violating decay modes of the K-mesons is given. Subsequently, some new developments in the field of CP-violation are reviewed and the question of time-reversal invariance and the status of CPT-invariance are briefly considered. 42 references

Foliated vector fields, the Godbillon-Vey invariant and the invariant I(F)

International Nuclear Information System (INIS)

Banyaga, A.; Landa, Alain Musesa

2004-03-01

We prove that if the invariant I(F) constructed in 'An invariant of contact structures and transversally oriented foliations', Ann. Global Analysis and Geom. 14(1996) 427-441 (A. Banyaga), through the Lie algebra of infinitesimal automorphisms of transversally oriented foliations F is trivial, then the Godbillon-Vey invariant GV (F) of F is also trivial, but that the converse is not true. For codimension one foliations, the restrictions I τ , (F) of I(F) to the Lie subalgebra of vector fields tangent to the leaves is the Reeb class R(F) of F. We also prove that if there exists a foliated vector field which is everywhere transverse to a codimension one foliation, then the Reeb class R(F) is trivial, hence so is the GV(F) invariant. (author)

Gauge invariance rediscovered

International Nuclear Information System (INIS)

Moriyasu, K.

1978-01-01

A pedagogical approach to gauge invariance is presented which is based on the analogy between gauge transformations and relativity. By using the concept of an internal space, purely geometrical arguments are used to teach the physical ideas behind gauge invariance. Many of the results are applicable to general gauge theories

Assessing cross-cultural differences through use of multiple-group invariance analyses.

Science.gov (United States)

Stein, Judith A; Lee, Jerry W; Jones, Patricia S

2006-12-01

The use of structural equation modeling in cross-cultural personality research has become a popular method for testing measurement invariance. In this report, we present an example of testing measurement invariance using the Sense of Coherence Scale of Antonovsky (1993) in 3 ethnic groups: Chinese, Japanese, and Whites. In a series of increasingly restrictive constraints on the measurement models of the 3 groups, we demonstrate how to assess differences among the groups. We also provide an example of construct validation.

Differential invariants in nonclassical models of hydrodynamics

Science.gov (United States)

Bublik, Vasily V.

2017-10-01

In this paper, differential invariants are used to construct solutions for equations of the dynamics of a viscous heat-conducting gas and the dynamics of a viscous incompressible fluid modified by nanopowder inoculators. To describe the dynamics of a viscous heat-conducting gas, we use the complete system of Navier—Stokes equations with allowance for heat fluxes. Mathematical description of the dynamics of liquid metals under high-energy external influences (laser radiation or plasma flow) includes, in addition to the Navier—Stokes system of an incompressible viscous fluid, also heat fluxes and processes of nonequilibrium crystallization of a deformable fluid. Differentially invariant solutions are a generalization of partially invariant solutions, and their active study for various models of continuous medium mechanics is just beginning. Differentially invariant solutions can also be considered as solutions with differential constraints; therefore, when developing them, the approaches and methods developed by the science schools of academicians N. N. Yanenko and A. F. Sidorov will be actively used. In the construction of partially invariant and differentially invariant solutions, there are overdetermined systems of differential equations that require a compatibility analysis. The algorithms for reducing such systems to involution in a finite number of steps are described by Cartan, Finikov, Kuranishi, and other authors. However, the difficultly foreseeable volume of intermediate calculations complicates their practical application. Therefore, the methods of computer algebra are actively used here, which largely helps in solving this difficult problem. It is proposed to use the constructed exact solutions as tests for formulas, algorithms and their software implementations when developing and creating numerical methods and computational program complexes. This combination of effective numerical methods, capable of solving a wide class of problems, with

Study of top and anti-top mass difference

CERN Document Server

Leedumrongwatthanakun, Saroch

2013-01-01

The invariance of the standard model under CPT transformations leads to the equality of particle and antiparticle masses. The recent measurements performed by the CMS experiment on the top anti-top mass difference are a test of such symmetry. In this work non-perturbative QCD effects, which may eventually lead to an apparent difference in the mass of a top and anti-top quark, are studied.

Link invariants from finite Coxeter racks

OpenAIRE

Nelson, Sam; Wieghard, Ryan

2008-01-01

We study Coxeter racks over $\\mathbb{Z}_n$ and the knot and link invariants they define. We exploit the module structure of these racks to enhance the rack counting invariants and give examples showing that these enhanced invariants are stronger than the unenhanced rack counting invariants.

Brain Oscillations Elicited by the Cold Pressor Test: A Putative Index of Untreated Essential Hypertension

OpenAIRE

Christos Papageorgiou; Efstathios Manios; Eleftheria Tsaltas; Eleni Koroboki; Maria Alevizaki; Elias Angelopoulos; Meletios-Athanasios Dimopoulos; Charalabos Papageorgiou; Nikolaos Zakopoulos

2017-01-01

Objective. Essential hypertension is associated with reduced pain sensitivity of unclear aetiology. This study explores this issue using the Cold Pressor Test (CPT), a reliable pain/stress model, comparing CPT-related EEG activity in first episode hypertensives and controls. Method. 22 untreated hypertensives and 18 matched normotensives underwent 24-hour ambulatory blood pressure monitoring (ABPM). EEG recordings were taken before, during, and after CPT exposure. Results. Significant group d...

Testing measurement invariance of the schizotypal personality questionnaire-brief scores across Spanish and Swiss adolescents.

Directory of Open Access Journals (Sweden)

Javier Ortuño-Sierra

Full Text Available BACKGROUND: Schizotypy is a complex construct intimately related to psychosis. Empirical evidence indicates that participants with high scores on schizotypal self-report are at a heightened risk for the later development of psychotic disorders. Schizotypal experiences represent the behavioural expression of liability for psychotic disorders. Previous factorial studies have shown that schizotypy is a multidimensional construct similar to that found in patients with schizophrenia. Specifically, using the Schizotypal Personality Questionnaire-Brief (SPQ-B, the three-dimensional model has been widely replicated. However, there has been no in-depth investigation of whether the dimensional structure underlying the SPQ-B scores is invariant across countries. METHODS: The main goal of this study was to examine the measurement invariance of the SPQ-B scores across Spanish and Swiss adolescents. The final sample was made up of 261 Spanish participants (51.7% men; M = 16.04 years and 241 Swiss participants (52.3% men; M = 15.94 years. RESULTS: The results indicated that Raine et al.'s three-factor model presented adequate goodness-of-fit indices. Moreover, the results supported the measurement invariance (configural and partial strong invariance of the SPQ-B scores across the two samples. Spanish participants scored higher on Interpersonal dimension than Swiss when latent means were compared. DISCUSSION: The study of measurement equivalence across countries provides preliminary evidence for the Raine et al.'s three-factor model and of the cross-cultural validity of the SPQ-B scores in adolescent population. Future studies should continue to examine the measurement invariance of the schizotypy and psychosis-risk syndromes across cultures.

Image mosaicking based on feature points using color-invariant values

Science.gov (United States)

Lee, Dong-Chang; Kwon, Oh-Seol; Ko, Kyung-Woo; Lee, Ho-Young; Ha, Yeong-Ho

2008-02-01

In the field of computer vision, image mosaicking is achieved using image features, such as textures, colors, and shapes between corresponding images, or local descriptors representing neighborhoods of feature points extracted from corresponding images. However, image mosaicking based on feature points has attracted more recent attention due to the simplicity of the geometric transformation, regardless of distortion and differences in intensity generated by camera motion in consecutive images. Yet, since most feature-point matching algorithms extract feature points using gray values, identifying corresponding points becomes difficult in the case of changing illumination and images with a similar intensity. Accordingly, to solve these problems, this paper proposes a method of image mosaicking based on feature points using color information of images. Essentially, the digital values acquired from a real digital color camera are converted to values of a virtual camera with distinct narrow bands. Values based on the surface reflectance and invariant to the chromaticity of various illuminations are then derived from the virtual camera values and defined as color-invariant values invariant to changing illuminations. The validity of these color-invariant values is verified in a test using a Macbeth Color-Checker under simulated illuminations. The test also compares the proposed method using the color-invariant values with the conventional SIFT algorithm. The accuracy of the matching between the feature points extracted using the proposed method is increased, while image mosaicking using color information is also achieved.

Study of T and CPT symmetries in semileptonic disintegrations of kaons neutral K{sup 0} and anti K{sup 0}; Etude des symetries T et CPT dans les desintegrations semileptoniques des kaons neutres K{sup 0} et anti K{sup 0}

Energy Technology Data Exchange (ETDEWEB)

Soares-Svagelski, A.

1996-06-05

This thesis begins by a presentation of the different symmetries such P, C, T, CP and CPT. Then, there is a phenomenon description of violation parameters of T, CPT and CP in the system of kaons neutral, the study system. It is shown how the violation of CP has been introduced in the super weak model then, in the standard model. Then, we have a description of the experience called CP LEAR with the presentation of apparatus and devices and the data acquisition. Before the analysis of semileptonic events, the selection of these events is detailed. The determination of parameters is followed by a discussion of gained values. The other measures of the experience are only little discussed. (N.C.). 67 refs., 65 figs., 14 tabs.

Rotation Invariance Neural Network

OpenAIRE

Li, Shiyuan

2017-01-01

Rotation invariance and translation invariance have great values in image recognition tasks. In this paper, we bring a new architecture in convolutional neural network (CNN) named cyclic convolutional layer to achieve rotation invariance in 2-D symbol recognition. We can also get the position and orientation of the 2-D symbol by the network to achieve detection purpose for multiple non-overlap target. Last but not least, this architecture can achieve one-shot learning in some cases using thos...

A numerical similarity approach for using retired Current Procedural Terminology (CPT) codes for electronic phenotyping in the Scalable Collaborative Infrastructure for a Learning Health System (SCILHS).

Science.gov (United States)

Klann, Jeffrey G; Phillips, Lori C; Turchin, Alexander; Weiler, Sarah; Mandl, Kenneth D; Murphy, Shawn N

2015-12-11

Interoperable phenotyping algorithms, needed to identify patient cohorts meeting eligibility criteria for observational studies or clinical trials, require medical data in a consistent structured, coded format. Data heterogeneity limits such algorithms' applicability. Existing approaches are often: not widely interoperable; or, have low sensitivity due to reliance on the lowest common denominator (ICD-9 diagnoses). In the Scalable Collaborative Infrastructure for a Learning Healthcare System (SCILHS) we endeavor to use the widely-available Current Procedural Terminology (CPT) procedure codes with ICD-9. Unfortunately, CPT changes drastically year-to-year - codes are retired/replaced. Longitudinal analysis requires grouping retired and current codes. BioPortal provides a navigable CPT hierarchy, which we imported into the Informatics for Integrating Biology and the Bedside (i2b2) data warehouse and analytics platform. However, this hierarchy does not include retired codes. We compared BioPortal's 2014AA CPT hierarchy with Partners Healthcare's SCILHS datamart, comprising three-million patients' data over 15 years. 573 CPT codes were not present in 2014AA (6.5 million occurrences). No existing terminology provided hierarchical linkages for these missing codes, so we developed a method that automatically places missing codes in the most specific "grouper" category, using the numerical similarity of CPT codes. Two informaticians reviewed the results. We incorporated the final table into our i2b2 SCILHS/PCORnet ontology, deployed it at seven sites, and performed a gap analysis and an evaluation against several phenotyping algorithms. The reviewers found the method placed the code correctly with 97 % precision when considering only miscategorizations ("correctness precision") and 52 % precision using a gold-standard of optimal placement ("optimality precision"). High correctness precision meant that codes were placed in a reasonable hierarchal position that a reviewer

Lorentz invariance with an invariant energy scale.

Science.gov (United States)

Magueijo, João; Smolin, Lee

2002-05-13

We propose a modification of special relativity in which a physical energy, which may be the Planck energy, joins the speed of light as an invariant, in spite of a complete relativity of inertial frames and agreement with Einstein's theory at low energies. This is accomplished by a nonlinear modification of the action of the Lorentz group on momentum space, generated by adding a dilatation to each boost in such a way that the Planck energy remains invariant. The associated algebra has unmodified structure constants. We also discuss the resulting modifications of field theory and suggest a modification of the equivalence principle which determines how the new theory is embedded in general relativity.

Further examination of embedded performance validity indicators for the Conners' Continuous Performance Test and Brief Test of Attention in a large outpatient clinical sample.

Science.gov (United States)

Sharland, Michael J; Waring, Stephen C; Johnson, Brian P; Taran, Allise M; Rusin, Travis A; Pattock, Andrew M; Palcher, Jeanette A

2018-01-01

Assessing test performance validity is a standard clinical practice and although studies have examined the utility of cognitive/memory measures, few have examined attention measures as indicators of performance validity beyond the Reliable Digit Span. The current study further investigates the classification probability of embedded Performance Validity Tests (PVTs) within the Brief Test of Attention (BTA) and the Conners' Continuous Performance Test (CPT-II), in a large clinical sample. This was a retrospective study of 615 patients consecutively referred for comprehensive outpatient neuropsychological evaluation. Non-credible performance was defined two ways: failure on one or more PVTs and failure on two or more PVTs. Classification probability of the BTA and CPT-II into non-credible groups was assessed. Sensitivity, specificity, positive predictive value, and negative predictive value were derived to identify clinically relevant cut-off scores. When using failure on two or more PVTs as the indicator for non-credible responding compared to failure on one or more PVTs, highest classification probability, or area under the curve (AUC), was achieved by the BTA (AUC = .87 vs. .79). CPT-II Omission, Commission, and Total Errors exhibited higher classification probability as well. Overall, these findings corroborate previous findings, extending them to a large clinical sample. BTA and CPT-II are useful embedded performance validity indicators within a clinical battery but should not be used in isolation without other performance validity indicators.

Noncommutative GUTs, Standard Model and C,P,T

International Nuclear Information System (INIS)

Aschieri, P.; Jurco, B.; Schupp, P.; Wess, J.

2003-01-01

Noncommutative Yang-Mills theories are sensitive to the choice of the representation that enters in the gauge kinetic term. We constrain this ambiguity by considering grand unified theories. We find that at first order in the noncommutativity parameter θ, SU(5) is not truly a unified theory, while SO(10) has a unique noncommutative generalization. In view of these results we discuss the noncommutative SM theory that is compatible with SO(10) GUT and find that there are no modifications to the SM gauge kinetic term at lowest order in θ. We study in detail the reality, Hermiticity and C,P,T properties of the Seiberg-Witten map and of the resulting effective actions expanded in ordinary fields. We find that in models of GUTs (or compatible with GUTs) right-handed fermions and left-handed ones appear with opposite Seiberg-Witten map

Noncommutative GUTs, Standard Model and C,P,T

Energy Technology Data Exchange (ETDEWEB)

Aschieri, P. E-mail: aschieri@theorie.physik.uni-muenchen.de; Jurco, B. E-mail: jurco@theorie.physik.uni-muenchen.de; Schupp, P. E-mail: p.schupp@iu-bremen.de; Wess, J. E-mail: wess@theorie.physik.uni-muenchen.de

2003-02-17

Noncommutative Yang-Mills theories are sensitive to the choice of the representation that enters in the gauge kinetic term. We constrain this ambiguity by considering grand unified theories. We find that at first order in the noncommutativity parameter {theta}, SU(5) is not truly a unified theory, while SO(10) has a unique noncommutative generalization. In view of these results we discuss the noncommutative SM theory that is compatible with SO(10) GUT and find that there are no modifications to the SM gauge kinetic term at lowest order in {theta}. We study in detail the reality, Hermiticity and C,P,T properties of the Seiberg-Witten map and of the resulting effective actions expanded in ordinary fields. We find that in models of GUTs (or compatible with GUTs) right-handed fermions and left-handed ones appear with opposite Seiberg-Witten map.

Modeling Item-Level and Step-Level Invariance Effects in Polytomous Items Using the Partial Credit Model

Science.gov (United States)

Gattamorta, Karina A.; Penfield, Randall D.; Myers, Nicholas D.

2012-01-01

Measurement invariance is a common consideration in the evaluation of the validity and fairness of test scores when the tested population contains distinct groups of examinees, such as examinees receiving different forms of a translated test. Measurement invariance in polytomous items has traditionally been evaluated at the item-level,…

New tests of cumulative prospect theory and the priority heuristic

Directory of Open Access Journals (Sweden)

Michael H. Birnbaum

2008-04-01

Full Text Available Previous tests of cumulative prospect theory (CPT and of the priority heuristic (PH found evidence contradicting these two models of risky decision making. However, those tests were criticized because they had characteristics that might ``trigger'' use of other heuristics. This paper presents new tests that avoid those characteristics. Expected values of the gambles are nearly equal in each choice. In addition, if a person followed expected value (EV, expected utility (EU, CPT, or PH in these tests, she would shift her preferences in the same direction as shifts in EV or EU. In contrast, the transfer of attention exchange model (TAX and a similarity model predict that people will reverse preferences in the opposite direction. Results contradict the PH, even when PH is modified to include a preliminary similarity evaluation using the PH parameters. New tests of probability-consequence interaction were also conducted. Strong interactions were observed, contrary to PH. These results add to the growing bodies of evidence showing that neither CPT nor PH is an accurate description of risky decision making.

The Dynamical Invariant of Open Quantum System

OpenAIRE

Wu, S. L.; Zhang, X. Y.; Yi, X. X.

2015-01-01

The dynamical invariant, whose expectation value is constant, is generalized to open quantum system. The evolution equation of dynamical invariant (the dynamical invariant condition) is presented for Markovian dynamics. Different with the dynamical invariant for the closed quantum system, the evolution of the dynamical invariant for the open quantum system is no longer unitary, and the eigenvalues of it are time-dependent. Since any hermitian operator fulfilling dynamical invariant condition ...

Zigzagging causility model of EPR correlations and on the interpretation of quantum mechanics

International Nuclear Information System (INIS)

de Beauregard, O.C.

1988-01-01

Being formalized inside the S-matrix scheme, the zigzagging causility model of EPR correlations has full Lorentz and CPT invariance. EPR correlations, proper or reversed, and Wheeler's smoky dragon metaphor are respectively pictured in a spacetime or in the momentum-energy space, as V-shaped, anti LAMBDA-shaped, or C-shaped ABC zigzags, with a summation at B over virtual states absolute value B> = *. The reversibility = * implies that causality is CPT-invariant, or arrowless, at the microlevel. Arrowed causality is a macroscopic emergence, corollary to wave retardation and probability increase. Factlike irreversibility states repression, not suppression, of blind statistical retrodiction- that is, of final cause

Hidden scale invariance of metals

DEFF Research Database (Denmark)

Hummel, Felix; Kresse, Georg; Dyre, Jeppe C.

2015-01-01

Density functional theory (DFT) calculations of 58 liquid elements at their triple point show that most metals exhibit near proportionality between the thermal fluctuations of the virial and the potential energy in the isochoric ensemble. This demonstrates a general “hidden” scale invariance...... of metals making the condensed part of the thermodynamic phase diagram effectively one dimensional with respect to structure and dynamics. DFT computed density scaling exponents, related to the Grüneisen parameter, are in good agreement with experimental values for the 16 elements where reliable data were...... available. Hidden scale invariance is demonstrated in detail for magnesium by showing invariance of structure and dynamics. Computed melting curves of period three metals follow curves with invariance (isomorphs). The experimental structure factor of magnesium is predicted by assuming scale invariant...

Reducing Lookups for Invariant Checking

DEFF Research Database (Denmark)

Thomsen, Jakob Grauenkjær; Clausen, Christian; Andersen, Kristoffer Just

2013-01-01

This paper helps reduce the cost of invariant checking in cases where access to data is expensive. Assume that a set of variables satisfy a given invariant and a request is received to update a subset of them. We reduce the set of variables to inspect, in order to verify that the invariant is still...

Cpt1a gene expression in peripheral blood mononuclear cells as an early biomarker of diet-related metabolic alterations

KAUST Repository

Diaz Rua, Ruben; Palou, Andreu; Oliver, Paula

2016-01-01

subjects at risk of developing diet-related diseases.Objective: We analysed PBMC expression of key energy homeostasis-related genes in a time-course analysis in order to find out early markers of metabolic alterations due to sustained intake of high-fat (HF) and highprotein (HP) diets.Design: We administered HF and HP diets (4 months) to adult Wistar rats in isocaloric conditions to a control diet, mainly to avoid overweight associated with the intake of hyperlipidic diets and, thus, to be able to characterise markers of metabolically obese normal-weight (MONW) syndrome. PBMC samples were collected at different time points of dietary treatment and expression of relevant energy homeostatic genes analysed by real-time reverse transcription-polymerase chain reaction. Serum parameters related with metabolic syndrome, as well as fat deposition in liver, were also analysed.Results: The most outstanding results were those obtained for the expression of the lipolytic gene carnitine palmitoyltransferase 1a (Cpt1a). Cpt1a expression in PBMC increased after only 1 month of exposure to both unbalanced diets, and this increased expression was maintained thereafter. Interestingly, in the case of the HF diet, Cpt1a expression was altered even in the absence of increased body weight but correlated with alterations such as higher insulin resistance, alteration of serum lipid profile and, particularly, increased fat deposition in liver, a feature characteristic of metabolic syndrome, which was even observed in animals fed with HP diet.Conclusions: We propose Cpt1a gene expression analysis in PBMC as an early biomarker of metabolic alterations associated with MONW phenotype due to the intake of isocaloric HF diets, as well as a marker of increased risk of metabolic diseases

Algorithms in invariant theory

CERN Document Server

Sturmfels, Bernd

2008-01-01

J. Kung and G.-C. Rota, in their 1984 paper, write: "Like the Arabian phoenix rising out of its ashes, the theory of invariants, pronounced dead at the turn of the century, is once again at the forefront of mathematics". The book of Sturmfels is both an easy-to-read textbook for invariant theory and a challenging research monograph that introduces a new approach to the algorithmic side of invariant theory. The Groebner bases method is the main tool by which the central problems in invariant theory become amenable to algorithmic solutions. Students will find the book an easy introduction to this "classical and new" area of mathematics. Researchers in mathematics, symbolic computation, and computer science will get access to a wealth of research ideas, hints for applications, outlines and details of algorithms, worked out examples, and research problems.

The Loneliness Questionnaire: Establishing Measurement Invariance Across Ethnic Groups.

Science.gov (United States)

Ritchwood, Tiarney D; Ebesutani, Chad K; Chin, Eu Gene; Young, John

2017-09-01

A state of loneliness describes an individual's perception of having dissatisfying social connections to others. Though it is notable across the life span, it may have particularly deleterious effects in childhood and adolescence, leading to increased risk of emotional impairment. The current study evaluates a widely used test of loneliness, the Loneliness Questionnaire, for measurement invariance across ethnic groups in a large, representative sample of youth in the 2nd to 12th grades ( N = 12,344; 41% African American) in Mississippi. Analyses were conducted using multigroup confirmatory factor analysis following a published, sequential method to examine invariance in form, factor loadings, and item intercepts. Overall, our results indicated that the instrument was invariant across ethnicities, suggesting that youth with equivalent manifest scores can be discerned as having comparable levels of latent loneliness. The loneliness scores also corresponded significantly with depression and anxiety scores for most subsamples, with one exception. These findings are discussed in the context of previous results comparing levels of loneliness across ethnicities. Additionally, the broader context of the need to expand invariance studies in instrumentation work is highlighted.

How Can Paresthesia After Zygomaticomaxillary Complex Fracture Be Determined After Long-Term Follow-Up? A New and Quantitative Evaluation Method Using Current Perception Threshold Testing.

Science.gov (United States)

Okochi, Masayuki; Ueda, Kazuki; Mochizuki, Yasushi; Okochi, Hiromi

2015-08-01

The aims of the present study were to analyze the effectiveness of current perception threshold (CPT) testing to determine patients' minor paresthesia of the infraorbital region after open reduction and internal fixation (ORIF) for unilateral zygomaticomaxillary bone fracture (UZF) and to clarify which nerve fiber was related to the paresthesia. We conducted a retrospective cohort study of patients who had undergone ORIF after UZF. We also performed neurosensory testing for healthy volunteers who served as the control group. The predictor variables were the period of measurement of Semmes-Weinstein monofilament (S-W) testing and CPT testing (preoperatively and 1 and 5 years postoperatively), measurement side, and disease status (UZF or control). The outcome variables were paresthesia status of the infraorbital nerve region and the results of S-W and CPT testing in both UZF and control groups. The differences in the S-W and CPT values between the affected and unaffected sides in the UZF group and between the UZF and control groups were analyzed by t test (P paresthesia at 1 and 5 years postoperatively. At 5 years postoperatively, the S-W values in all patients showed normalization. From the results of CPT testing, only the A-β fiber function showed significant improvement at 5 years postoperatively. The CPT test was an effective sensory test for determining minor paresthesia that could not be detected using S-W testing. Paresthesia of the infraorbital nerve region was caused by the damaged A-δ and C fibers. Copyright © 2015 American Association of Oral and Maxillofacial Surgeons. Published by Elsevier Inc. All rights reserved.

Testing measurement invariance in the International Social Survey Program Health 2011 – the mental well-being scale

NARCIS (Netherlands)

van Deurzen, I.A.; Roosma, F.

2014-01-01

Purpose In the present contribution we address the measurement invariance of a new mental well-being scale of three items that was applied in the International Social Survey Program (ISSP) Health 2011 module. Our aim is to establish if and for how many countries (partial) scalar invariance is

Cartan invariants and event horizon detection

Science.gov (United States)

Brooks, D.; Chavy-Waddy, P. C.; Coley, A. A.; Forget, A.; Gregoris, D.; MacCallum, M. A. H.; McNutt, D. D.

2018-04-01

We show that it is possible to locate the event horizon of a black hole (in arbitrary dimensions) by the zeros of certain Cartan invariants. This approach accounts for the recent results on the detection of stationary horizons using scalar polynomial curvature invariants, and improves upon them since the proposed method is computationally less expensive. As an application, we produce Cartan invariants that locate the event horizons for various exact four-dimensional and five-dimensional stationary, asymptotically flat (or (anti) de Sitter), black hole solutions and compare the Cartan invariants with the corresponding scalar curvature invariants that detect the event horizon.

A numerical study on an optimum design of a Cross-flow type Power Turbine (CPT)

International Nuclear Information System (INIS)

Ha, Jin Ho; Kim, Chul Ho

2008-01-01

A wind turbine is one of the most popular energy conversion systems to generate electricity from the natural renewable energy source and an axial-flow type wind turbine is commonly used system for the generation electricity in the wind farm nowadays. In this study, a cross-flow type turbine has been studied for the application of wind turbine for electricity generation. The target capacity of the electric power generation of the model wind turbine developing in this project is 12volts-150A/H(about 1.8Kw). The important design parameters of the model turbine impeller are the inlet and exit angle of the turbine blade, number of blade, hub/tip ratio and exit flow angle of the housing. In this study, the radial equilibrium theorem was used to decide the inlet and exit angle of the model impeller blade and CFD technique was incorporated to have performance analysis of the design model power turbine for the optimum design of the geometry of the Cross-flow Power Turbine impeller and Casing. In CFD, Navier-Stokes equation is solved with the SIMPLEC method in a general coordinates system. Realizable k-ε turbulent model with MARS scheme was used for evaluating torque of each blade in the Cross-flow Power Turbine (CPT). From the result, the designed CPT with 24 impeller blades at α=40 .deg. and β=85 .deg. of turbine blade angle was estimated to generate 1.2Nm of the indicated torque and 200watts of the indicated power. On the basis of the rules of similarity, the generating power capacity of the real size CPT that is eight times longer than the model impeller is predicted to have an 1.6kW of the output power (about 12V-130A/H or 24V-65A/H)

Teen Dating Violence, Sexual Harassment, and Bullying Among Middle School Youth: Examining Measurement Invariance by Gender.

Science.gov (United States)

Cutbush, Stacey; Williams, Jason

2016-12-01

This study investigated measurement invariance by gender among commonly used teen dating violence (TDV), sexual harassment, and bullying measures. Data were collected from one cohort of seventh-grade middle school students (N = 754) from four schools. Using structural equation modeling, exploratory and confirmatory factor analyses assessed measurement models and tested measurement invariance by gender for aggression measures. Analyses invoked baseline data only. Physical and psychological TDV perpetration measures achieved strict measurement invariance, while bullying perpetration demonstrated partial strict invariance. Electronic TDV and sexual harassment perpetration achieved metric/scalar invariance. Study findings lend validation to prior and future studies using these measures with similar populations. Future research should increase attention to measurement development, refinement, and testing among study measures. © 2016 The Authors. Journal of Research on Adolescence © 2016 Society for Research on Adolescence.

A cross-national analysis of measurement invariance of the Satisfaction With Life Scale.

Science.gov (United States)

Whisman, Mark A; Judd, Charles M

2016-02-01

Measurement invariance of the Satisfaction With Life Scale (SWLS) was examined in probability samples of adults 50-79 years of age living in the United States, England, and Japan. Confirmatory factor analysis modeling was used to test for multigroup measurement invariance of a single-factor structure of the SWLS. Results support a single-factor structure of the SWLS across the 3 countries, with tests of measurement invariance of the SWLS supporting its configural invariance and metric invariance. These results suggest that the SWLS may be used as a single-factor measure of life satisfaction in the United States, England, and Japan, and that it is appropriate to compare correlates of the SWLS in middle-aged and older adults across these 3 countries. However, results provided evidence for only partial scalar invariance, with the intercept for SWLS Item 4 varying across countries. Cross-national comparisons of means revealed a lower mean at the latent variable level for the Japanese sample than for the other 2 samples. In addition, over and above the latent mean difference, the Japanese sample also manifested a significantly lower intercept on Item 4. Implications of the findings for research on cross-national comparisons of life satisfaction in European American and East Asian countries are discussed. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

Mass generation within conformal invariant theories

International Nuclear Information System (INIS)

Flato, M.; Guenin, M.

1981-01-01

The massless Yang-Mills theory is strongly conformally invariant and renormalizable; however, when masses are introduced the theory becomes nonrenormalizable and weakly conformally invariant. Conditions which recover strong conformal invariance are discussed in the letter. (author)

Conformal invariance an introduction to loops, interfaces and stochastic Loewner evolution

CERN Document Server

Karevski, Dragi

2012-01-01

Conformal invariance has been a spectacularly successful tool in advancing our understanding of the two-dimensional phase transitions found in classical systems at equilibrium. This volume sharpens our picture of the applications of conformal invariance, introducing non-local observables such as loops and interfaces before explaining how they arise in specific physical contexts. It then shows how to use conformal invariance to determine their properties. Moving on to cover key conceptual developments in conformal invariance, the book devotes much of its space to stochastic Loewner evolution (SLE), detailing SLE’s conceptual foundations as well as extensive numerical tests. The chapters then elucidate SLE’s use in geometric phase transitions such as percolation or polymer systems, paying particular attention to surface effects. As clear and accessible as it is authoritative, this publication is as suitable for non-specialist readers and graduate students alike.

Coordinate-invariant regularization

International Nuclear Information System (INIS)

Halpern, M.B.

1987-01-01

A general phase-space framework for coordinate-invariant regularization is given. The development is geometric, with all regularization contained in regularized DeWitt Superstructures on field deformations. Parallel development of invariant coordinate-space regularization is obtained by regularized functional integration of the momenta. As representative examples of the general formulation, the regularized general non-linear sigma model and regularized quantum gravity are discussed. copyright 1987 Academic Press, Inc

A parts-per-billion measurement of the antiproton magnetic moment.

Science.gov (United States)

Smorra, C; Sellner, S; Borchert, M J; Harrington, J A; Higuchi, T; Nagahama, H; Tanaka, T; Mooser, A; Schneider, G; Bohman, M; Blaum, K; Matsuda, Y; Ospelkaus, C; Quint, W; Walz, J; Yamazaki, Y; Ulmer, S

2017-10-18

Precise comparisons of the fundamental properties of matter-antimatter conjugates provide sensitive tests of charge-parity-time (CPT) invariance, which is an important symmetry that rests on basic assumptions of the standard model of particle physics. Experiments on mesons, leptons and baryons have compared different properties of matter-antimatter conjugates with fractional uncertainties at the parts-per-billion level or better. One specific quantity, however, has so far only been known to a fractional uncertainty at the parts-per-million level: the magnetic moment of the antiproton, . The extraordinary difficulty in measuring with high precision is caused by its intrinsic smallness; for example, it is 660 times smaller than the magnetic moment of the positron. Here we report a high-precision measurement of in units of the nuclear magneton μ N with a fractional precision of 1.5 parts per billion (68% confidence level). We use a two-particle spectroscopy method in an advanced cryogenic multi-Penning trap system. Our result  = -2.7928473441(42)μ N (where the number in parentheses represents the 68% confidence interval on the last digits of the value) improves the precision of the previous best measurement by a factor of approximately 350. The measured value is consistent with the proton magnetic moment, μ p  = 2.792847350(9)μ N , and is in agreement with CPT invariance. Consequently, this measurement constrains the magnitude of certain CPT-violating effects to below 1.8 × 10 -24 gigaelectronvolts, and a possible splitting of the proton-antiproton magnetic moments by CPT-odd dimension-five interactions to below 6 × 10 -12 Bohr magnetons.

Invariant sets for Windows

CERN Document Server

Morozov, Albert D; Dragunov, Timothy N; Malysheva, Olga V

1999-01-01

This book deals with the visualization and exploration of invariant sets (fractals, strange attractors, resonance structures, patterns etc.) for various kinds of nonlinear dynamical systems. The authors have created a special Windows 95 application called WInSet, which allows one to visualize the invariant sets. A WInSet installation disk is enclosed with the book.The book consists of two parts. Part I contains a description of WInSet and a list of the built-in invariant sets which can be plotted using the program. This part is intended for a wide audience with interests ranging from dynamical

Development of novel tasks for studying view-invariant object recognition in rodents: Sensitivity to scopolamine.

Science.gov (United States)

Mitchnick, Krista A; Wideman, Cassidy E; Huff, Andrew E; Palmer, Daniel; McNaughton, Bruce L; Winters, Boyer D

2018-05-15

The capacity to recognize objects from different view-points or angles, referred to as view-invariance, is an essential process that humans engage in daily. Currently, the ability to investigate the neurobiological underpinnings of this phenomenon is limited, as few ethologically valid view-invariant object recognition tasks exist for rodents. Here, we report two complementary, novel view-invariant object recognition tasks in which rodents physically interact with three-dimensional objects. Prior to experimentation, rats and mice were given extensive experience with a set of 'pre-exposure' objects. In a variant of the spontaneous object recognition task, novelty preference for pre-exposed or new objects was assessed at various angles of rotation (45°, 90° or 180°); unlike control rodents, for whom the objects were novel, rats and mice tested with pre-exposed objects did not discriminate between rotated and un-rotated objects in the choice phase, indicating substantial view-invariant object recognition. Secondly, using automated operant touchscreen chambers, rats were tested on pre-exposed or novel objects in a pairwise discrimination task, where the rewarded stimulus (S+) was rotated (180°) once rats had reached acquisition criterion; rats tested with pre-exposed objects re-acquired the pairwise discrimination following S+ rotation more effectively than those tested with new objects. Systemic scopolamine impaired performance on both tasks, suggesting involvement of acetylcholine at muscarinic receptors in view-invariant object processing. These tasks present novel means of studying the behavioral and neural bases of view-invariant object recognition in rodents. Copyright © 2018 Elsevier B.V. All rights reserved.

What's hampering measurement invariance : Detecting non-invariant items using clusterwise simultaneous component analysis

NARCIS (Netherlands)

De Roover, K.; Timmerman, Marieke; De Leersnyder, J.; Mesquita, B.; Ceulemans, Eva

2014-01-01

The issue of measurement invariance is ubiquitous in the behavioral sciences nowadays as more and more studies yield multivariate multigroup data. When measurement invariance cannot be established across groups, this is often due to different loadings on only a few items. Within the multigroup CFA

Structural invariance of the Schroedinger equation and chronoprojective geometry

International Nuclear Information System (INIS)

Burdet, G.; Perrin, M.

1983-07-01

We describe an extension of the chronoprojective geometry and show how its automorphisms are related to the invariance properties of the Schroedinger equation describing a quantum test particle in any Newton-Cartan structure

Tests of local Lorentz invariance violation of gravity in the standard model extension with pulsars.

Science.gov (United States)

Shao, Lijing

2014-03-21

The standard model extension is an effective field theory introducing all possible Lorentz-violating (LV) operators to the standard model and general relativity (GR). In the pure-gravity sector of minimal standard model extension, nine coefficients describe dominant observable deviations from GR. We systematically implemented 27 tests from 13 pulsar systems to tightly constrain eight linear combinations of these coefficients with extensive Monte Carlo simulations. It constitutes the first detailed and systematic test of the pure-gravity sector of minimal standard model extension with the state-of-the-art pulsar observations. No deviation from GR was detected. The limits of LV coefficients are expressed in the canonical Sun-centered celestial-equatorial frame for the convenience of further studies. They are all improved by significant factors of tens to hundreds with existing ones. As a consequence, Einstein's equivalence principle is verified substantially further by pulsar experiments in terms of local Lorentz invariance in gravity.

Gender Differences among Children with ADHD on Continuous Performance Tests: A Meta-Analytic Review

Science.gov (United States)

Hasson, Ramzi; Fine, Jodene Goldenring

2012-01-01

Objective: Gender differences among children with ADHD are not well understood. The continuous performance test (CPT) is the most frequently used direct measure of inattention and impulsivity. This meta-analysis compared CPT performance between boys and girls with and without ADHD. Method: All peer-reviewed ADHD studies published between 1980 and…

Analyzing power for π-p charge exchange and a test of isospin invariance up to eta threshold

International Nuclear Information System (INIS)

Wightman, J.A.; Eichon, A.D.; Kim, G.J.; Mokhtari, A.; Nefkens, B.M.K.; Fitzgerald, D.H.; Sadler, M.E.

1987-01-01

The analyzing power for π - p→π 0 n has been measured at five incident momenta from 547 to 687 MeV/c using a transversely polarized target. Data were obtained with scintillation counters at 10 angles simultaneously covering the range -0.9 ≤ cosθ/sub c.m.//sup π/ ≤ 0.9. Our results and those of Kim et al. are used for a model-independent test of isospin invariance which is based on the triangle inequalities applied to the transversity-up as well as the transversity-down cross sections. No evidence is found for isospin violation

Determination of the T- and CPT-violation parameters in the neutral-kaon system using the Bell-Steinberger relation and data from CPLEAR

CERN Document Server

Apostolakis, Alcibiades J; Backenstoss, Gerhard; Bargassa, P; Behnke, O; Benelli, A; Bertin, V; Blanc, F; Bloch, P; Carlson, P J; Carroll, M; Cawley, E; Chertok, M B; Danielsson, M; Dejardin, M; Derré, J; Ealet, A; Eleftheriadis, C; Fetscher, W; Fidecaro, Maria; Filipcic, A; Francis, D; Fry, J; Gabathuler, Erwin; Gamet, R; Gerber, H J; Go, A; Haselden, A; Hayman, P J; Henry-Coüannier, F; Hollander, R W; Jon-And, K; Kettle, P R; Kokkas, P; Kreuger, R; Le Gac, R; Leimgruber, F; Mandic, I; Manthos, N; Marel, Gérard; Mikuz, M; Miller, J; Montanet, François; Müller, A; Nakada, Tatsuya; Pagels, B; Papadopoulos, I M; Pavlopoulos, P; Polivka, G; Rickenbach, R; Roberts, B L; Sakelliou, L; Ruf, T; Schäfer, M; Schaller, L A; Schietinger, T; Schopper, A; Tauscher, Ludwig; Thibault, C; Touchard, F; Touramanis, C; van Eijk, C W E; Vlachos, S; Weber, P; Wigger, O; Wolter, M; Zavrtanik, D; Zimmerman, D

1999-01-01

Data from the CPLEAR experiment, together with the most recent world averages for some of the neutral-kaon parameters, were constrained with the Bell--Steinberger (or unitarity) relation, allowing the T-violation parameter $\\ree$ and the CPT-violation parameter $\\imd$ of the neutral-kaon mixing matrix to be determined with an increased accuracy: $\\ree = (164.9 \\pm 2.5)\\times 10^{-5}$, $\\imd = ( 2.4 \\pm 5.0)\\times 10^{-5}$. Moreover, the constraint allows the CPT-violation parameter for the neutral-kaon semileptonic decays, $\\rey$, to be determined for the first time. The $\\Delta S \

Cpt1a gene expression in peripheral blood mononuclear cells as an early biomarker of diet-related metabolic alterations

Directory of Open Access Journals (Sweden)

Rubén Díaz-Rúa

2016-11-01

Full Text Available Background: Research on biomarkers that provide early information about the development of future metabolic alterations is an emerging discipline. Gene expression analysis in peripheral blood mononuclear cells (PBMC is a promising tool to identify subjects at risk of developing diet-related diseases. Objective: We analysed PBMC expression of key energy homeostasis-related genes in a time-course analysis in order to find out early markers of metabolic alterations due to sustained intake of high-fat (HF and high-protein (HP diets. Design: We administered HF and HP diets (4 months to adult Wistar rats in isocaloric conditions to a control diet, mainly to avoid overweight associated with the intake of hyperlipidic diets and, thus, to be able to characterise markers of metabolically obese normal-weight (MONW syndrome. PBMC samples were collected at different time points of dietary treatment and expression of relevant energy homeostatic genes analysed by real-time reverse transcription-polymerase chain reaction. Serum parameters related with metabolic syndrome, as well as fat deposition in liver, were also analysed. Results: The most outstanding results were those obtained for the expression of the lipolytic gene carnitine palmitoyltransferase 1a (Cpt1a. Cpt1a expression in PBMC increased after only 1 month of exposure to both unbalanced diets, and this increased expression was maintained thereafter. Interestingly, in the case of the HF diet, Cpt1a expression was altered even in the absence of increased body weight but correlated with alterations such as higher insulin resistance, alteration of serum lipid profile and, particularly, increased fat deposition in liver, a feature characteristic of metabolic syndrome, which was even observed in animals fed with HP diet. Conclusions: We propose Cpt1a gene expression analysis in PBMC as an early biomarker of metabolic alterations associated with MONW phenotype due to the intake of isocaloric HF diets, as

Gauge-invariant cosmological density perturbations

International Nuclear Information System (INIS)

Sasaki, Misao.

1986-06-01

Gauge-invariant formulation of cosmological density perturbation theory is reviewed with special emphasis on its geometrical aspects. Then the gauge-invariant measure of the magnitude of a given perturbation is presented. (author)

Symmetry-violating kaon decays

International Nuclear Information System (INIS)

Herczeg, P.

1979-01-01

The content of this talk comprises two parts. In the first, an analysis of the muon number violating decay modes of the K-mesons is given. Subsequently, some new developments in the field of CP-violation are reviewed and the question of time-reversal invariance and the status of CPT-invariance are briefly considered. (auth)

Identification of invariant measures of interacting systems

International Nuclear Information System (INIS)

Chen Jinwen

2004-01-01

In this paper we provide an approach for identifying certain mixture representations of some invariant measures of interacting stochastic systems. This is related to the problem of ergodicity of certain extremal invariant measures that are translation invariant. Corresponding to these, results concerning the existence of invariant measures and certain weak convergence of the systems are also provided

Age-related invariance of abilities measured with the Wechsler Adult Intelligence Scale-IV.

Science.gov (United States)

Sudarshan, Navaneetham J; Bowden, Stephen C; Saklofske, Donald H; Weiss, Lawrence G

2016-11-01

Assessment of measurement invariance across populations is essential for meaningful comparison of test scores, and is especially relevant where repeated measurements are required for educational assessment or clinical diagnosis. Establishing measurement invariance legitimizes the assumption that test scores reflect the same psychological trait in different populations or across different occasions. Examination of Wechsler Adult Intelligence Scale-Fourth Edition (WAIS-IV) U.S. standardization samples revealed that a first-order 5-factor measurement model was best fitting across 9 age groups from 16 years to 69 years. Strong metric invariance was found for 3 of 5 factors and partial intercept invariance for the remaining 2. Pairwise comparisons of adjacent age groups supported the inference that cognitive-trait group differences are manifested by group differences in the test scores. In educational and clinical settings these findings provide theoretical and empirical support to interpret changes in the index or subtest scores as reflecting changes in the corresponding cognitive abilities. Further, where clinically relevant, the subtest score composites can be used to compare changes in respective cognitive abilities. The model was supported in the Canadian standardization data with pooled age groups but the sample sizes were not adequate for detailed examination of separate age groups in the Canadian sample. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

An ignored cause of red urine in children: rhabdomyolysis due to carnitine palmitoyltransferase II (CPT-II) deficiency.

Science.gov (United States)

Melek, Engin; Bulut, Fatma Derya; Atmış, Bahriye; Yılmaz, Berna Şeker; Bayazıt, Aysun Karabay; Mungan, Neslihan Önenli

2017-02-01

Carnitine palmitoyltransferase II (CPT-II) deficiency is an autosomal recessively inherited disorder involving the β-oxidation of long-chain fatty acids, which leads to rhabdomyolysis and subsequent acute renal failure. The clinical phenotype varies from a severe infantile form to a milder muscle form. Here, we report a 9-year-old boy referred to our hospital for the investigation of hematuria with a 2-day history of dark urine and malaise. As no erythrocytes in the microscopic examination of the urine and hemoglobinuria were present, myoglobinuria due to rhabdomyolysis was the most probable cause of dark urine. After excluding the other causes of rhabdomyolysis, with the help of metabolic investigations, the patient was suspected to have CPT-II deficiency, the most common cause of metabolic rhabdomyolysis. Our aim in presenting this case is to emphasize considering rhabdomyolysis in the differential diagnosis of dark urine in order to prevent recurrent rhabdomyolysis and renal injury.

Quantum-gravity phenomenology, Lorentz symmetry, and the SME

International Nuclear Information System (INIS)

Lehnert, Ralf

2007-01-01

Violations of spacetime symmetries have recently been identified as promising signatures for physics underlying the Standard Model. The present talk gives an overview over various topics in this field: The motivations for spacetime-symmetry research, including some mechanisms for Lorentz breaking, are reviewed. An effective field theory called the Standard-Model Extension (SME) for the description of the resulting low-energy effects is introduced, and some experimental tests of Lorentz and CPT invariance are discussed

The measurement invariance of job diagnostic survey (JDS) across three university student groups

Energy Technology Data Exchange (ETDEWEB)

Martinez-Gomez, M.; Marin-Garcia, J.A.; Girado Omeara, M.

2016-07-01

The main purpose of this study is to apply a multigroup confirmatory analysis to examine the measurement invariance (MI) of the adapted version of the Job Diagnosis Survey (JDS) as a measurement tool that analyses the relationship between the features of teaching methodologies with university students’ motivation and satisfaction across data collected on different degrees and academic years. Design/methodology/approach: Confirmatory factor analysis was carried out using a multigroup structural equation model, using the program EQS 6.1 to test the invariance of the adapted version of JDS in a sample constituted by 535 student of a Spanish public university. The assessment of invariance included the levels of configural, metric, scalar, covariance and latent variables invariance. Several goodness-of-fit measures were assessed... (Author)

75 FR 30041 - Medicare Program; Public Meeting in Calendar Year 2010 for New Clinical Laboratory Tests Payment...

Science.gov (United States)

2010-05-28

... specified list of new Clinical Procedural Terminology (CPT) codes for clinical laboratory tests in calendar... are codified at 42 CFR part 414, subpart G. A newly created Current Procedural Terminology (CPT) code..., Medicare--Hospital Insurance; and Program No. 93.774, Medicare-- Supplementary Medical Insurance Program...

Constructing Invariant Fairness Measures for Surfaces

DEFF Research Database (Denmark)

Gravesen, Jens; Ungstrup, Michael

1998-01-01

of the size of this vector field is used as the fairness measure on the family.Six basic 3rd order invariants satisfying two quadratic equations are defined. They form a complete set in the sense that any invariant 3rd order function can be written as a function of the six basic invariants together...

On logarithmic extensions of local scale-invariance

International Nuclear Information System (INIS)

Henkel, Malte

2013-01-01

Ageing phenomena far from equilibrium naturally present dynamical scaling and in many situations this may be generalised to local scale-invariance. Generically, the absence of time-translation-invariance implies that each scaling operator is characterised by two independent scaling dimensions. Building on analogies with logarithmic conformal invariance and logarithmic Schrödinger-invariance, this work proposes a logarithmic extension of local scale-invariance, without time-translation-invariance. Carrying this out requires in general to replace both scaling dimensions of each scaling operator by Jordan cells. Co-variant two-point functions are derived for the most simple case of a two-dimensional logarithmic extension. Their form is compared to simulational data for autoresponse functions in several universality classes of non-equilibrium ageing phenomena

Invariant recognition drives neural representations of action sequences.

Directory of Open Access Journals (Sweden)

Andrea Tacchetti

2017-12-01

Full Text Available Recognizing the actions of others from visual stimuli is a crucial aspect of human perception that allows individuals to respond to social cues. Humans are able to discriminate between similar actions despite transformations, like changes in viewpoint or actor, that substantially alter the visual appearance of a scene. This ability to generalize across complex transformations is a hallmark of human visual intelligence. Advances in understanding action recognition at the neural level have not always translated into precise accounts of the computational principles underlying what representations of action sequences are constructed by human visual cortex. Here we test the hypothesis that invariant action discrimination might fill this gap. Recently, the study of artificial systems for static object perception has produced models, Convolutional Neural Networks (CNNs, that achieve human level performance in complex discriminative tasks. Within this class, architectures that better support invariant object recognition also produce image representations that better match those implied by human and primate neural data. However, whether these models produce representations of action sequences that support recognition across complex transformations and closely follow neural representations of actions remains unknown. Here we show that spatiotemporal CNNs accurately categorize video stimuli into action classes, and that deliberate model modifications that improve performance on an invariant action recognition task lead to data representations that better match human neural recordings. Our results support our hypothesis that performance on invariant discrimination dictates the neural representations of actions computed in the brain. These results broaden the scope of the invariant recognition framework for understanding visual intelligence from perception of inanimate objects and faces in static images to the study of human perception of action sequences.

Nonlocal, yet translation invariant, constraints for rotationally invariant slave bosons

Science.gov (United States)

Ayral, Thomas; Kotliar, Gabriel

The rotationally-invariant slave boson (RISB) method is a lightweight framework allowing to study the low-energy properties of complex multiorbital problems currently out of the reach of more comprehensive, yet more computationally demanding methods such as dynamical mean field theory. In the original formulation of this formalism, the slave-boson constraints can be made nonlocal by enlarging the unit cell and viewing the quantum states enclosed in this new unit cell as molecular levels. In this work, we extend RISB to constraints which are nonlocal while preserving translation invariance. We apply this extension to the Hubbard model.

The measurement invariance of job diagnostic survey (JDS across three university student groups

Directory of Open Access Journals (Sweden)

Monica Martinez-Gomez

2016-02-01

Full Text Available Purpose: The main purpose of this study is to apply a multigroup confirmatory analysis to examine the measurement invariance (MI of the adapted version of the Job Diagnosis Survey (JDS as a measurement tool that analyses the relationship between the features of teaching methodologies with university students’ motivation and satisfaction across data collected on different degrees and academic years. Design/methodology/approach: Confirmatory factor analysis was carried out using a multigroup structural equation model, using the program EQS 6.1 to test the invariance of the adapted version of JDS in a sample constituted by 535 student of a Spanish public university. The assessment of invariance included the levels of configural, metric, scalar, covariance and latent variables invariance. Several goodness-of-fit measures were assessed. Findings: The results show that measurements are equivalent at the configural, metric, covariance and latent factors invariance. Although the hypotheses of scalar invariance is rejected, results suggest that JDS is partial strict invariant and has satisfactory psychometric properties on all samples. Research limitations/implications: The sample is framed in university students aged between 18 and 30 and for a questionnaire on teaching methodology and students' satisfaction in the context of a Spanish university and the generalization to other questionnaire, or population, should be proved with specific data. Furthermore, the sample size is rather small. Originality/value: In the current process of change that is taking place in universities according to the plan developed by the European Space of Higher Education, focused on increasing the student skills, validate instruments as the satisfaction scale of JDS, are necessary to evaluate students’ satisfaction with new active methodologies. These findings are useful for researchers since they add the first sample in which the MI of a student’s satisfaction survey

Analytic invariants of boundary links

OpenAIRE

Garoufalidis, Stavros; Levine, Jerome

2001-01-01

Using basic topology and linear algebra, we define a plethora of invariants of boundary links whose values are power series with noncommuting variables. These turn out to be useful and elementary reformulations of an invariant originally defined by M. Farber.

Isomorph invariance of Couette shear flows simulated by the SLLOD equations of motion

DEFF Research Database (Denmark)

Separdar, Leila; Bailey, Nicholas; Schrøder, Thomas

2013-01-01

fluctuations of virial and potential energy. Such systems have good isomorphs (curves in the thermodynamic phase diagram along which structural, dynamical, and some thermodynamic quantities are invariant when expressed in reduced units). The SLLOD equations of motion were used to simulate Couette shear flows......Non-equilibrium molecular dynamics simulations were performed to study the thermodynamic, structural, and dynamical properties of the single-component Lennard-Jones and the Kob-Andersen binary Lennard-Jones liquids. Both systems are known to have strong correlations between equilibrium thermal...... of the two systems. We show analytically that these equations are isomorph invariant provided the reduced strain rate is fixed along the isomorph. Since isomorph invariance is generally only approximate, a range of strain rates were simulated to test for the predicted invariance, covering both the linear...

Evaluation of Mycology Laboratory Proficiency Testing

Science.gov (United States)

Reilly, Andrew A.; Salkin, Ira F.; McGinnis, Michael R.; Gromadzki, Sally; Pasarell, Lester; Kemna, Maggi; Higgins, Nancy; Salfinger, Max

1999-01-01

Changes over the last decade in overt proficiency testing (OPT) regulations have been ostensibly directed at improving laboratory performance on patient samples. However, the overt (unblinded) format of the tests and regulatory penalties associated with incorrect values allow and encourage laboratorians to take extra precautions with OPT analytes. As a result OPT may measure optimal laboratory performance instead of the intended target of typical performance attained during routine patient testing. This study addresses this issue by evaluating medical mycology OPT and comparing its fungal specimen identification error rates to those obtained in a covert (blinded) proficiency testing (CPT) program. Identifications from 188 laboratories participating in the New York State mycology OPT from 1982 to 1994 were compared with the identifications of the same fungi recovered from patient specimens in 1989 and 1994 as part of the routine procedures of 88 of these laboratories. The consistency in the identification of OPT specimens was sufficient to make accurate predictions of OPT error rates. However, while the error rates in OPT and CPT were similar for Candida albicans, significantly higher error rates were found in CPT for Candida tropicalis, Candida glabrata, and other common pathogenic fungi. These differences may, in part, be due to OPT’s use of ideal organism representatives cultured under optimum growth conditions. This difference, as well as the organism-dependent error rate differences, reflects the limitations of OPT as a means of assessing the quality of routine laboratory performance in medical mycology. PMID:10364601

Summational invariants

International Nuclear Information System (INIS)

Mackrodt, C.; Reeh, H.

1997-01-01

General summational invariants, i.e., conservation laws acting additively on asymptotic particle states, are investigated within a classical framework for point particles with nontrivial scattering. copyright 1997 American Institute of Physics

Alabama Parenting Questionnaire-9: Longitudinal Measurement Invariance Across Parents and Youth During the Transition to High School.

Science.gov (United States)

Gross, Thomas J; Fleming, Charles B; Mason, W Alex; Haggerty, Kevin P

2017-07-01

The Alabama Parenting Questionnaire nine-item short form (APQ-9) is an often used assessment of parenting in research and applied settings. It uses parent and youth ratings for three scales: Positive Parenting, Inconsistent Discipline, and Poor Supervision. The purpose of this study is to examine the longitudinal invariance of the APQ-9 for both parents and youth, and the multigroup invariance between parents and youth during the transition from middle school to high school. Parent and youth longitudinal configural, metric, and scalar invariance for the APQ-9 were supported when tested separately. However, the multigroup invariance tests indicated that scalar invariance was not achieved between parent and youth ratings. Essentially, parent and youth mean scores for Positive Parenting, Inconsistent Discipline, and Poor Supervision can be independently compared across the transition from middle school to high school. However, comparing parent and youth scores across the APQ-9 scales may not be meaningful.

Link invariants for flows in higher dimensions

International Nuclear Information System (INIS)

Garcia-Compean, Hugo; Santos-Silva, Roberto

2010-01-01

Linking numbers in higher dimensions and their generalization including gauge fields are studied in the context of BF theories. The linking numbers associated with n-manifolds with smooth flows generated by divergence-free p-vector fields, endowed with an invariant flow measure, are computed in the context of quantum field theory. They constitute invariants of smooth dynamical systems (for nonsingular flows) and generalize previous proposals of invariants. In particular, they generalize Arnold's asymptotic Hopf invariant from three to higher dimensions. This invariant is generalized by coupling with a non-Abelian gauge flat connection with nontrivial holonomy. The computation of the asymptotic Jones-Witten invariants for flows is naturally extended to dimension n=2p+1. Finally, we give a possible interpretation and implementation of these issues in the context of 11-dimensional supergravity and string theory.

Dynamical topological invariant after a quantum quench

Science.gov (United States)

Yang, Chao; Li, Linhu; Chen, Shu

2018-02-01

We show how to define a dynamical topological invariant for one-dimensional two-band topological systems after a quantum quench. By analyzing general two-band models of topological insulators, we demonstrate that the reduced momentum-time manifold can be viewed as a series of submanifolds S2, and thus we are able to define a dynamical topological invariant on each of the spheres. We also unveil the intrinsic relation between the dynamical topological invariant and the difference in the topological invariant of the initial and final static Hamiltonian. By considering some concrete examples, we illustrate the calculation of the dynamical topological invariant and its geometrical meaning explicitly.

Phenomenology of local scale invariance: from conformal invariance to dynamical scaling

International Nuclear Information System (INIS)

Henkel, Malte

2002-01-01

Statistical systems displaying a strongly anisotropic or dynamical scaling behaviour are characterized by an anisotropy exponent θ or a dynamical exponent z. For a given value of θ (or z), we construct local scale transformations, which can be viewed as scale transformations with a space-time-dependent dilatation factor. Two distinct types of local scale transformations are found. The first type may describe strongly anisotropic scaling of static systems with a given value of θ, whereas the second type may describe dynamical scaling with a dynamical exponent z. Local scale transformations act as a dynamical symmetry group of certain non-local free-field theories. Known special cases of local scale invariance are conformal invariance for θ=1 and Schroedinger invariance for θ=2. The hypothesis of local scale invariance implies that two-point functions of quasi primary operators satisfy certain linear fractional differential equations, which are constructed from commuting fractional derivatives. The explicit solution of these yields exact expressions for two-point correlators at equilibrium and for two-point response functions out of equilibrium. A particularly simple and general form is found for the two-time auto response function. These predictions are explicitly confirmed at the uniaxial Lifshitz points in the ANNNI and ANNNS models and in the aging behaviour of simple ferromagnets such as the kinetic Glauber-Ising model and the kinetic spherical model with a non-conserved order parameter undergoing either phase-ordering kinetics or non-equilibrium critical dynamics

Noether symmetries, energy-momentum tensors, and conformal invariance in classical field theory

International Nuclear Information System (INIS)

Pons, Josep M.

2011-01-01

In the framework of classical field theory, we first review the Noether theory of symmetries, with simple rederivations of its essential results, with special emphasis given to the Noether identities for gauge theories. With this baggage on board, we next discuss in detail, for Poincare invariant theories in flat spacetime, the differences between the Belinfante energy-momentum tensor and a family of Hilbert energy-momentum tensors. All these tensors coincide on shell but they split their duties in the following sense: Belinfante's tensor is the one to use in order to obtain the generators of Poincare symmetries and it is a basic ingredient of the generators of other eventual spacetime symmetries which may happen to exist. Instead, Hilbert tensors are the means to test whether a theory contains other spacetime symmetries beyond Poincare. We discuss at length the case of scale and conformal symmetry, of which we give some examples. We show, for Poincare invariant Lagrangians, that the realization of scale invariance selects a unique Hilbert tensor which allows for an easy test as to whether conformal invariance is also realized. Finally we make some basic remarks on metric generally covariant theories and classical field theory in a fixed curved background.

Quantifying Translation-Invariance in Convolutional Neural Networks

OpenAIRE

Kauderer-Abrams, Eric

2017-01-01

A fundamental problem in object recognition is the development of image representations that are invariant to common transformations such as translation, rotation, and small deformations. There are multiple hypotheses regarding the source of translation invariance in CNNs. One idea is that translation invariance is due to the increasing receptive field size of neurons in successive convolution layers. Another possibility is that invariance is due to the pooling operation. We develop a simple ...

Invariant measures in brain dynamics

International Nuclear Information System (INIS)

Boyarsky, Abraham; Gora, Pawel

2006-01-01

This note concerns brain activity at the level of neural ensembles and uses ideas from ergodic dynamical systems to model and characterize chaotic patterns among these ensembles during conscious mental activity. Central to our model is the definition of a space of neural ensembles and the assumption of discrete time ensemble dynamics. We argue that continuous invariant measures draw the attention of deeper brain processes, engendering emergent properties such as consciousness. Invariant measures supported on a finite set of ensembles reflect periodic behavior, whereas the existence of continuous invariant measures reflect the dynamics of nonrepeating ensemble patterns that elicit the interest of deeper mental processes. We shall consider two different ways to achieve continuous invariant measures on the space of neural ensembles: (1) via quantum jitters, and (2) via sensory input accompanied by inner thought processes which engender a 'folding' property on the space of ensembles

A case study of liquefaction risk analysis based on the thickness and depth of the liquefaction layer using CPT and electric resistivity data in the Hinode area, Itako City, Ibaraki Prefecture, Japan

Science.gov (United States)

Jinguuji, Motoharu; Toprak, Selcuk

2017-12-01

The Hinode area of Itako City in Ibaraki Prefecture, Japan, suffered some of the most severe liquefaction damage of any areas in the Great Eastern Japan Earthquake in 2011. This liquefaction damage has been investigated by Itako City, as well as by universities and research institutes in Japan. The National Institute of Advanced Industrial Science and Technology (AIST) has carried out numerous investigations along the Tone River, and in particular, intensive surveys were done in the Hinode area. We have conducted a risk analysis based on the thickness and depth of the liquefaction layer measured using cone penetration testing (CPT) data and electric resistivity data obtained in the Hinode area. The distribution of the risk estimated from CPT at 143 points, and that obtained from analysis of the resistivity survey data, agreed with the distribution of actual damage. We also carried out conventional risk analyses method using the liquefaction resistance factor (FL) and liquefaction potential index (PL) methods with CPT data. The results show high PL values over the entire area, but their distribution did not agree well with actual damage in some parts of the study area. Because the analysis of the thickness and depth of the liquefaction layer, using geophysical prospecting methods, can cover a widespread area, this method will be very useful in investigating liquefaction risk, especially for gas and water pipelines.

Scoring correction for MMPI-2 Hs scale with patients experiencing a traumatic brain injury: a test of measurement invariance.

Science.gov (United States)

Alkemade, Nathan; Bowden, Stephen C; Salzman, Louis

2015-02-01

It has been suggested that MMPI-2 scoring requires removal of some items when assessing patients after a traumatic brain injury (TBI). Gass (1991. MMPI-2 interpretation and closed head injury: A correction factor. Psychological assessment, 3, 27-31) proposed a correction procedure in line with the hypothesis that MMPI-2 endorsement may be affected by symptoms of TBI. This study assessed the validity of the Gass correction procedure. A sample of patients with a TBI (n = 242), and a random subset of the MMPI-2 normative sample (n = 1,786). The correction procedure implies a failure of measurement invariance across populations. This study examined measurement invariance of one of the MMPI-2 scales (Hs) that includes TBI correction items. A four-factor model of the MMPI-2 Hs items was defined. The factor model was found to meet the criteria for partial measurement invariance. Analysis of the change in sensitivity and specificity values implied by partial measurement invariance failed to indicate significant practical impact of partial invariance. Overall, the results support continued use of all Hs items to assess psychological well-being in patients with TBI. © The Author 2014. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

The usage of color invariance in SURF

Science.gov (United States)

Meng, Gang; Jiang, Zhiguo; Zhao, Danpei

2009-10-01

SURF (Scale Invariant Feature Transform) is a robust local invariant feature descriptor. However, SURF is mainly designed for gray images. In order to make use of the information provided by color (mainly RGB channels), this paper presents a novel colored local invariant feature descriptor, CISURF (Color Invariance based SURF). The proposed approach builds the descriptors in a color invariant space, which stems from Kubelka-Munk model and provides more valuable information than the gray space. Compared with the conventional SURF and SIFT descriptors, the experimental results show that descriptors created by CISURF is more robust to the circumstance changes such as the illumination direction, illumination intensity, and the viewpoints, and are more suitable for the deep space background objects.

Anisotropic Weyl invariance

Energy Technology Data Exchange (ETDEWEB)

Perez-Nadal, Guillem [Universidad de Buenos Aires, Buenos Aires (Argentina)

2017-07-15

We consider a non-relativistic free scalar field theory with a type of anisotropic scale invariance in which the number of coordinates ''scaling like time'' is generically greater than one. We propose the Cartesian product of two curved spaces, the metric of each space being parameterized by the other space, as a notion of curved background to which the theory can be extended. We study this type of geometries, and find a family of extensions of the theory to curved backgrounds in which the anisotropic scale invariance is promoted to a local, Weyl-type symmetry. (orig.)

The invariant theory of matrices

CERN Document Server

Concini, Corrado De

2017-01-01

This book gives a unified, complete, and self-contained exposition of the main algebraic theorems of invariant theory for matrices in a characteristic free approach. More precisely, it contains the description of polynomial functions in several variables on the set of m\\times m matrices with coefficients in an infinite field or even the ring of integers, invariant under simultaneous conjugation. Following Hermann Weyl's classical approach, the ring of invariants is described by formulating and proving the first fundamental theorem that describes a set of generators in the ring of invariants, and the second fundamental theorem that describes relations between these generators. The authors study both the case of matrices over a field of characteristic 0 and the case of matrices over a field of positive characteristic. While the case of characteristic 0 can be treated following a classical approach, the case of positive characteristic (developed by Donkin and Zubkov) is much harder. A presentation of this case...

An experimental limit on the charge of antihydrogen

CERN Document Server

Amole, C; Baquero-Ruiz, M; Bertsche, W; Butler, E; Capra, A; Cesar, C L; Charlton, M; Eriksson, S; Fajans, J; Friesen, T; Fujiwara, M C; Gill, D R; Gutierrez, A; Hangst, J S; Hardy, W N; Hayden, M E; Isaac, C A; Jonsell, S; Kurchaninov, L; Little, A; Madsen, N; McKenna, J T K; Menary, S; Napoli, S C; Nolan, P; Olchanski, K; Olin, A; Povilus, A; Pusa, P; Rasmussen, C Ø; Robicheaux, F; Sarid, E; Silveira, D M; So, C; Tharp, T D; Thompson, R I; Van der Werf, D P; Vendeiro, Z; Wurtele, J S; Zhmoginov, A I; Charman, A E

2014-01-01

The properties of antihydrogen are expected to be identical to those of hydrogen, and any differences would constitute a profound challenge to the fundamental theories of physics. The most commonly discussed antiatom-based tests of these theories are searches for antihydrogen-hydrogen spectral differences (tests of CPT (charge-parity-time) invariance) or gravitational differences (tests of the weak equivalence principle). Here we, the ALPHA Collaboration, report a different and somewhat unusual test of CPT and of quantum anomaly cancellation. A retrospective analysis of the influence of electric fields on antihydrogen atoms released from the ALPHA trap finds a mean axial deflection of 4.1±3.4 mm for an average axial electric field of 0.51 V mm−1. Combined with extensive numerical modelling, this measurement leads to a bound on the charge Qe of antihydrogen of Q=(−1.3±1.1±0.4) × 10−8. Here, e is the unit charge, and the errors are from statistics and systematic effects.

Longitudinal Invariance of the Wechsler Intelligence Scale for Children--Fourth Edition in a Referral Sample

Science.gov (United States)

Richerson, Lindsay P.; Watkins, Marley W.; Beaujean, A. Alexander

2014-01-01

Measurement invariance of the Wechsler Intelligence Scale for Children--Fourth Edition (WISC-IV) was investigated with a group of 352 students eligible for psychoeducational evaluations tested, on average, 2.8 years apart. Configural, metric, and scalar invariance were found. However, the error variance of the Coding subtest was not constant…

Scale invariant Volkov–Akulov supergravity

Energy Technology Data Exchange (ETDEWEB)

Ferrara, S., E-mail: sergio.ferrara@cern.ch [Th-Ph Department, CERN, CH-1211 Geneva 23 (Switzerland); INFN – Laboratori Nazionali di Frascati, Via Enrico Fermi 40, 00044 Frascati (Italy); Department of Physics and Astronomy, University of California, Los Angeles, CA 90095-1547 (United States); Porrati, M., E-mail: mp9@nyu.edu [Th-Ph Department, CERN, CH-1211 Geneva 23 (Switzerland); CCPP, Department of Physics, NYU, 4 Washington Pl., New York, NY 10003 (United States); Sagnotti, A., E-mail: sagnotti@sns.it [Th-Ph Department, CERN, CH-1211 Geneva 23 (Switzerland); Scuola Normale Superiore and INFN, Piazza dei Cavalieri 7, 56126 Pisa (Italy)

2015-10-07

A scale invariant goldstino theory coupled to supergravity is obtained as a standard supergravity dual of a rigidly scale-invariant higher-curvature supergravity with a nilpotent chiral scalar curvature. The bosonic part of this theory describes a massless scalaron and a massive axion in a de Sitter Universe.

Memory assessment and depression: testing for factor structure and measurement invariance of the Wechsler Memory Scale-Fourth Edition across a clinical and matched control sample.

Science.gov (United States)

Pauls, Franz; Petermann, Franz; Lepach, Anja Christina

2013-01-01

Between-group comparisons are permissible and meaningfully interpretable only if diagnostic instruments are proved to measure the same latent dimensions across different groups. Addressing this issue, the present study was carried out to provide a rigorous test of measurement invariance. Confirmatory factor analyses were used to determine which model solution could best explain memory performance as measured by the Wechsler Memory Scale-Fourth Edition (WMS-IV) in a clinical depression sample and in healthy controls. Multigroup confirmatory factor analysis was conducted to evaluate the evidence for measurement invariance. A three-factor model solution including the dimensions of auditory memory, visual memory, and visual working memory was identified to best fit the data in both samples, and measurement invariance was partially satisfied. The results supported clinical utility of the WMS-IV--that is, auditory and visual memory performances of patients with depressive disorders are interpretable on the basis of the WMS-IV standardization data. However, possible differences in visual working memory functions between healthy and depressed individuals could restrict comparisons of the WMS-IV working memory index.

On the invariance principle

Energy Technology Data Exchange (ETDEWEB)

Moller-Nielsen, Thomas [University of Oxford (United Kingdom)

2014-07-01

Physicists and philosophers have long claimed that the symmetries of our physical theories - roughly speaking, those transformations which map solutions of the theory into solutions - can provide us with genuine insight into what the world is really like. According to this 'Invariance Principle', only those quantities which are invariant under a theory's symmetries should be taken to be physically real, while those quantities which vary under its symmetries should not. Physicists and philosophers, however, are generally divided (or, indeed, silent) when it comes to explaining how such a principle is to be justified. In this paper, I spell out some of the problems inherent in other theorists' attempts to justify this principle, and sketch my own proposed general schema for explaining how - and when - the Invariance Principle can indeed be used as a legitimate tool of metaphysical inference.

A functional LMO invariant for Lagrangian cobordisms

DEFF Research Database (Denmark)

Cheptea, Dorin; Habiro, Kazuo; Massuyeau, Gwénaël

2008-01-01

Lagrangian cobordisms are three-dimensional compact oriented cobordisms between once-punctured surfaces, subject to some homological conditions. We extend the Le–Murakami–Ohtsuki invariant of homology three-spheres to a functor from the category of Lagrangian cobordisms to a certain category...... of Jacobi diagrams. We prove some properties of this functorial LMO invariant, including its universality among rational finite-type invariants of Lagrangian cobordisms. Finally, we apply the LMO functor to the study of homology cylinders from the point of view of their finite-type invariants....

High fructose consumption induces DNA methylation at PPARα and CPT1A promoter regions in the rat liver

Energy Technology Data Exchange (ETDEWEB)

Ohashi, Koji [Department of Clinical Biochemistry, Fujita Health University School of Health Sciences, Toyoake (Japan); Munetsuna, Eiji [Department of Biochemistry, Fujita Health University School of Medicine, Toyoake (Japan); Yamada, Hiroya, E-mail: hyamada@fujita-hu.ac.jp [Department of Hygiene, Fujita Health University School of Medicine, Toyoake (Japan); Ando, Yoshitaka [Department of Joint Research Laboratory of Clinical Medicine, Fujita Health University Hospital, Toyoake (Japan); Yamazaki, Mirai; Taromaru, Nao; Nagura, Ayuri; Ishikawa, Hiroaki [Department of Clinical Biochemistry, Fujita Health University School of Health Sciences, Toyoake (Japan); Suzuki, Koji [Department of Public Health, Fujita Health University School of Health Sciences, Toyoake (Japan); Teradaira, Ryoji [Department of Clinical Biochemistry, Fujita Health University School of Health Sciences, Toyoake (Japan); Hashimoto, Shuji [Department of Hygiene, Fujita Health University School of Medicine, Toyoake (Japan)

2015-12-04

DNA methylation status is affected by environmental factors, including nutrition. Fructose consumption is considered a risk factor for the conditions that make up metabolic syndrome such as dyslipidemia. However, the pathogenetic mechanism by which fructose consumption leads to metabolic syndrome is unclear. Based on observations that epigenetic modifications are closely related to induction of metabolic syndrome, we hypothesized that fructose-induced metabolic syndrome is caused by epigenetic alterations. Male SD rats were designated to receive water or 20% fructose solution for 14 weeks. mRNA levels for peroxisome proliferator-activated receptor alpha (PPARα) and carnitine palmitoyltransferase 1A (CPT1A) was analyzed using Real-time PCR. Restriction digestion and real-time PCR (qAMP) was used for the analysis of DNA methylation status. Hepatic lipid accumulation was also observed by fructose intake. Fructose feeding also significantly decreased mRNA levels for PPARα and CPT1A. qAMP analysis demonstrated the hypermethylation of promoter regions of PPARα and CTP1A genes. Fructose-mediated attenuated gene expression may be mediated by alterations of DNA methylation status, and pathogenesis of metabolic syndrome induced by fructose relates to DNA methylation status. - Highlights: • No general consensus has been reached regarding the molecular mechanisms of the pathogenesis of fructose-induced diseases. • Significant increase in hepatic total methylation level was observed after fructose-supplemented feeding. • Fructose feeding significantly decreased mRNA levels for PPARα and CPT1A. • qAMP analysis demonstrated the hypermethylation of promoter regions of PPARα and CTP1A genes. • Fructose-mediated attenuated gene expression may be mediated by alterations of DNA methylation status in rat liver.

High fructose consumption induces DNA methylation at PPARα and CPT1A promoter regions in the rat liver

International Nuclear Information System (INIS)

Ohashi, Koji; Munetsuna, Eiji; Yamada, Hiroya; Ando, Yoshitaka; Yamazaki, Mirai; Taromaru, Nao; Nagura, Ayuri; Ishikawa, Hiroaki; Suzuki, Koji; Teradaira, Ryoji; Hashimoto, Shuji

2015-01-01

DNA methylation status is affected by environmental factors, including nutrition. Fructose consumption is considered a risk factor for the conditions that make up metabolic syndrome such as dyslipidemia. However, the pathogenetic mechanism by which fructose consumption leads to metabolic syndrome is unclear. Based on observations that epigenetic modifications are closely related to induction of metabolic syndrome, we hypothesized that fructose-induced metabolic syndrome is caused by epigenetic alterations. Male SD rats were designated to receive water or 20% fructose solution for 14 weeks. mRNA levels for peroxisome proliferator-activated receptor alpha (PPARα) and carnitine palmitoyltransferase 1A (CPT1A) was analyzed using Real-time PCR. Restriction digestion and real-time PCR (qAMP) was used for the analysis of DNA methylation status. Hepatic lipid accumulation was also observed by fructose intake. Fructose feeding also significantly decreased mRNA levels for PPARα and CPT1A. qAMP analysis demonstrated the hypermethylation of promoter regions of PPARα and CTP1A genes. Fructose-mediated attenuated gene expression may be mediated by alterations of DNA methylation status, and pathogenesis of metabolic syndrome induced by fructose relates to DNA methylation status. - Highlights: • No general consensus has been reached regarding the molecular mechanisms of the pathogenesis of fructose-induced diseases. • Significant increase in hepatic total methylation level was observed after fructose-supplemented feeding. • Fructose feeding significantly decreased mRNA levels for PPARα and CPT1A. • qAMP analysis demonstrated the hypermethylation of promoter regions of PPARα and CTP1A genes. • Fructose-mediated attenuated gene expression may be mediated by alterations of DNA methylation status in rat liver.

SYMPATHETIC NEURAL AND HEMODYNAMIC RESPONSES DURING COLD PRESSOR TEST IN ELDERLY BLACKS AND WHITES

Science.gov (United States)

Okada, Yoshiyuki; Jarvis, Sara S.; Best, Stuart A.; Edwards, Jeffrey G.; Hendrix, Joseph M.; Adams-Huet, Beverley; Vongpatanasin, Wanpen; Levine, Benjamin D.; Fu, Qi

2016-01-01

The sympathetic response during the cold pressor test (CPT) has been reported to be greater in young blacks than whites, especially in those with a family history of hypertension. Since blood pressure (BP) increases with age, we evaluated whether elderly blacks have greater sympathetic activation during CPT than age-matched whites. BP, heart rate (HR), cardiac output (Qc), and muscle sympathetic nerve activity (MSNA) were measured during supine baseline, 2-min CPT, and 3-min recovery in 47 elderly [68±7 (SD) yrs] volunteers (12 blacks, 35 whites). Baseline BP, HR, Qc, or MSNA did not differ between races. Systolic and diastolic BP (DBP) and HR increased during CPT (all P0.05). Qc increased during CPT and up to 30 sec of recovery in both groups, but was lower in blacks than whites. MSNA increased during CPT in both groups (both P<0.001); the increase in burst frequency was similar between groups, while the increase in total activity was smaller in blacks (P=0.030 for interaction). Peak change (Δ) in DBP was correlated with Δ total activity at 1 min into CPT in both blacks (r=0.78, P=0.003) and whites (r=0.43, P=0.009), while the slope was significantly greater in blacks (P=0.007). Thus, elderly blacks have smaller sympathetic and central hemodynamic (e.g., Qc) responses, but a greater pressor response for a given sympathetic activation during CPT than elderly whites. This response may stem from augmented sympathetic vascular transduction, greater sympathetic activation to other vascular bed(s), and/or enhanced non-adrenergically mediated vasoconstriction in elderly blacks. PMID:27021009

No two ageisms are the same: testing measurement invariance in ageism experience across Europe

Czech Academy of Sciences Publication Activity Database

Trusinová, Romana

2014-01-01

Roč. 17, č. 6 (2014), s. 659-675 ISSN 1364-5579 R&D Projects: GA MŠk LM2010012 Institutional support: RVO:68378025 Keywords : measurement invariance * ageism * European Social Survey Subject RIV: AO - Sociology, Demography Impact factor: 0.784, year: 2014

Continuous Integrated Invariant Inference, Phase I

Data.gov (United States)

National Aeronautics and Space Administration — The proposed project will develop a new technique for invariant inference and embed this and other current invariant inference and checking techniques in an...

Scale invariant Volkov–Akulov supergravity

Directory of Open Access Journals (Sweden)

S. Ferrara

2015-10-01

Full Text Available A scale invariant goldstino theory coupled to supergravity is obtained as a standard supergravity dual of a rigidly scale-invariant higher-curvature supergravity with a nilpotent chiral scalar curvature. The bosonic part of this theory describes a massless scalaron and a massive axion in a de Sitter Universe.

Experimental tests of confinement scale invariance on JET, DIIID, ASDEX Upgrade and CMOD

International Nuclear Information System (INIS)

Christiansen, J.P.; Cordey, J.G.; Budny, R.

2001-01-01

An international collaboration between JET, DIIID, AUG and CMOD has resulted in four sets of Tokamak discharges which are approximately identical as regards a set of dimensionless plasma variables. The data demonstrates some measure of scale invariance of local and global confinement but a more accurate matching of scaled density, power etc. is required to make firmer conclusions. (author)

On the zigzagging causility model of EPR correlations and on the interpretation of quantum mechanics

Science.gov (United States)

de Beauregard, O. Costa

1988-09-01

Being formalized inside the S-matrix scheme, the zigzagging causility model of EPR correlations has full Lorentz and CPT invariance. EPR correlations, proper or reversed, and Wheeler's smoky dragon metaphor are respectively pictured in spacetime or in the momentum-energy space, as V-shaped, A-shaped, or C-shaped ABC zigzags, with a summation at B over virtual states |B> = *. The formal parrallelism breaks down at the level of interpretation because (A|C) = ||2. CPT invariance implies the Fock and Watanabe principle that, in quantum mechanics, retarded (advanced) waves are used for prediction (retrodiction), an expression of which is = = , with |Φ> denoting a preparation, |Ψ> a measurement, and U the evolution operator. The transformation |Ψ> = |UΦ> or |Φ> = |U-1Ψ> exchanges the “preparation representation” and the “measurement representation” of a system and is ancillary in the formalization of the quantum chance game by the “wavelike algebra” of conditional amplitude. In 1935 EPR overlooked that a conditional amplitude = Σ between the two distant measurements is at stake, and that only measurements actually performed do make sense. The reversibility = * implies that causality is CPT-invariant, or arrowless, at the microlevel. Arrowed causality is a macroscopic emergence, corollary to wave retardation and probability increase. Factlike irreversibility states repression, not suppression, of “blind statistical retrodiction”—that is, of “final cause.”

Simulation of the Position Resolution of a Scintillation Detector

CERN Document Server

Templ, Sebastian; Sauerzopf, Clemens

In the Standard Model of particle physics, CPT symmetry is regarded as invariant. In order to test this prediction, the ASACUSA collaboration (“Atomic Spectroscopy And Collisions Using Slow Antiprotons”) aims to make a very precise measurement of the hyperfine structure of antihydrogen with a Rabi-like experiment. The compar- ison of the experimentally-obtained antihydrogen transition frequencies with those of hydrogen allows for a direct test of CPT symmetry. The spectrometer line of the ASACUSA HBAR-GSHFS (“Antihydrogen ground state hyperfine splitting”) experiment consists of a particle source, a spin flip-in- ducing microwave cavity, a spin-analyzing sextupole magnet, and a detector. In the course of the work for this thesis, a single scintillation detector as used in the hodoscopes of the detector at the end of the spectrometer line was simulated using the particle physics toolkit Geant4. Subsequent analysis of the simulation data allows for an estimate of the minimal uncertainty in determining t...

Brain Oscillations Elicited by the Cold Pressor Test: A Putative Index of Untreated Essential Hypertension.

Science.gov (United States)

Papageorgiou, Christos; Manios, Efstathios; Tsaltas, Eleftheria; Koroboki, Eleni; Alevizaki, Maria; Angelopoulos, Elias; Dimopoulos, Meletios-Athanasios; Papageorgiou, Charalabos; Zakopoulos, Nikolaos

2017-01-01

Essential hypertension is associated with reduced pain sensitivity of unclear aetiology. This study explores this issue using the Cold Pressor Test (CPT), a reliable pain/stress model, comparing CPT-related EEG activity in first episode hypertensives and controls. 22 untreated hypertensives and 18 matched normotensives underwent 24-hour ambulatory blood pressure monitoring (ABPM). EEG recordings were taken before, during, and after CPT exposure. Significant group differences in CPT-induced EEG oscillations were covaried with the most robust cardiovascular differentiators by means of a Canonical Analysis. Positive correlations were noted between ABPM variables and Delta (1-4 Hz) oscillations during the tolerance phase; in high-alpha (10-12 Hz) oscillations during the stress unit and posttest phase; and in low-alpha (8-10 Hz) oscillations during CPT phases overall. Negative correlations were found between ABPM variables and Beta2 oscillations (16.5-20 Hz) during the posttest phase and Gamma (28.5-45 Hz) oscillations during the CPT phases overall. These relationships were localised at several sites across the cerebral hemispheres with predominance in the right hemisphere and left frontal lobe. These findings provide a starting point for increasing our understanding of the complex relationships between cerebral activation and cardiovascular functioning involved in regulating blood pressure changes.

Brain Delivery of Drug and MRI Contrast Agent: Detection and Quantitative Determination of Brain Deposition of CPT-Glu Using LC-MS/MS and Gd-DTPA Using Magnetic Resonance Imaging

Science.gov (United States)

Tabanor, Kayann; Lee, Phil; Kiptoo, Paul; Choi, In-Young; Sherry, Erica B.; Eagle, Cheyenne Sun; Williams, Todd D.; Siahaan, Teruna J.

2015-01-01

Successful treatment and diagnosis of neurological diseases depend on reliable delivery of molecules across the blood-brain barrier (BBB), which restricts penetration of pharmaceutical drugs and diagnostic agents into the brain. Thus, developing new non-invasive strategies to improve drug delivery across the BBB is critically needed. This study was aimed at evaluating the activity of HAV6 peptide (Ac-SHAVSS-NH2) in improving brain delivery of camptothecin-glutamate (CPT-Glu) conjugate and gadolinium-diethylenetriaminepentaacetate (Gd-DTPA) contrast agent in Sprague-Dawley rats. Brain delivery of both CPT-Glu and Gd-DTPA was evaluated in an in situ rat brain perfusion model in the presence and absence of HAV6 peptide (1.0 mM). Gd-DTPA (0.6 mmol/kg) was intravenously (i.v.) administered with and without HAV6 peptide (0.019 mmol/kg) in rats. The detection and quantification of CPT-Glu and Gd-DTPA in the brain were carried out by LC-MS/MS and quantitative magnetic resonance imaging (MRI), respectively. Rats perfused with CPT-Glu in combination with HAV6 had significantly higher deposition of drug in the brain compared to CPT-Glu alone. MRI results also showed that administration of Gd-DTPA in the presence of HAV6 peptide led to significant accumulation of Gd-DTPA in various regions of the brain in both the in situ rat brain perfusion and in vivo studies. All observations taken together indicate that HAV6 peptide can disrupt the BBB and enhance delivery of small molecules into the brain. PMID:26705088

Brain Delivery of Drug and MRI Contrast Agent: Detection and Quantitative Determination of Brain Deposition of CPT-Glu Using LC-MS/MS and Gd-DTPA Using Magnetic Resonance Imaging.

Science.gov (United States)

Tabanor, Kayann; Lee, Phil; Kiptoo, Paul; Choi, In-Young; Sherry, Erica B; Eagle, Cheyenne Sun; Williams, Todd D; Siahaan, Teruna J

2016-02-01

Successful treatment and diagnosis of neurological diseases depend on reliable delivery of molecules across the blood-brain barrier (BBB), which restricts penetration of pharmaceutical drugs and diagnostic agents into the brain. Thus, developing new noninvasive strategies to improve drug delivery across the BBB is critically needed. This study was aimed at evaluating the activity of HAV6 peptide (Ac-SHAVSS-NH2) in improving brain delivery of camptothecin-glutamate (CPT-Glu) conjugate and gadolinium-diethylenetriaminepentaacetate (Gd-DTPA) contrast agent in Sprague-Dawley rats. Brain delivery of both CPT-Glu and Gd-DTPA was evaluated in an in situ rat brain perfusion model in the presence and absence of HAV6 peptide (1.0 mM). Gd-DTPA (0.6 mmol/kg) was intravenously (iv) administered with and without HAV6 peptide (0.019 mmol/kg) in rats. The detection and quantification of CPT-Glu and Gd-DTPA in the brain were carried out by LC-MS/MS and quantitative magnetic resonance imaging (MRI), respectively. Rats perfused with CPT-Glu in combination with HAV6 had significantly higher deposition of drug in the brain compared to CPT-Glu alone. MRI results also showed that administration of Gd-DTPA in the presence of HAV6 peptide led to significant accumulation of Gd-DTPA in various regions of the brain in both the in situ rat brain perfusion and in vivo studies. All observations taken together indicate that HAV6 peptide can disrupt the BBB and enhance delivery of small molecules into the brain.

Universal happiness? Cross-cultural measurement invariance of scales assessing positive mental health.

Science.gov (United States)

Bieda, Angela; Hirschfeld, Gerrit; Schönfeld, Pia; Brailovskaia, Julia; Zhang, Xiao Chi; Margraf, Jürgen

2017-04-01

Research into positive aspects of the psyche is growing as psychologists learn more about the protective role of positive processes in the development and course of mental disorders, and about their substantial role in promoting mental health. With increasing globalization, there is strong interest in studies examining positive constructs across cultures. To obtain valid cross-cultural comparisons, measurement invariance for the scales assessing positive constructs has to be established. The current study aims to assess the cross-cultural measurement invariance of questionnaires for 6 positive constructs: Social Support (Fydrich, Sommer, Tydecks, & Brähler, 2009), Happiness (Subjective Happiness Scale; Lyubomirsky & Lepper, 1999), Life Satisfaction (Diener, Emmons, Larsen, & Griffin, 1985), Positive Mental Health Scale (Lukat, Margraf, Lutz, van der Veld, & Becker, 2016), Optimism (revised Life Orientation Test [LOT-R]; Scheier, Carver, & Bridges, 1994) and Resilience (Schumacher, Leppert, Gunzelmann, Strauss, & Brähler, 2004). Participants included German (n = 4,453), Russian (n = 3,806), and Chinese (n = 12,524) university students. Confirmatory factor analyses and measurement invariance testing demonstrated at least partial strong measurement invariance for all scales except the LOT-R and Subjective Happiness Scale. The latent mean comparisons of the constructs indicated differences between national groups. Potential methodological and cultural explanations for the intergroup differences are discussed. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

Search for CPT Violation with the FOCUS Experiment and Measurement of Λ_b lifetime in the decay Λ_b → J / Ψ Lambda with the D0 Experiment

Energy Technology Data Exchange (ETDEWEB)

Kryemadhi, Abaz [Indiana Univ., Bloomington, IN (United States)

2004-12-01

This dissertation describes two different projects from two different experiments. We have performed a search for CPT violation in neutral charm meson oscillations using data from the FOCUS Experiment. While flavor mixing in the charm sector is predicted to be small in the Standard Model, it is still possible to investigate CPT violation through a study of the proper time dependence of a CPT asymmetry in right-sign decay rates for D⁰ → K^- π⁺ and $\\bar{D}$⁰ → K⁺π^-. This asymmetry is related to the CPT violating complex parameter ξ and the mixing parameters x and y: A_CPT ∞ Reξy - Imξx. We determine a 95% confidence level limit of -0.0068 < Reξy - Imξx < 0.0234. Within the framework of the Standard Model Extension incorporating general CPT violation, we also find 95% confidence level limits for the expressions involving coefficients of Lorentz violation of (-2.8 < N(x,y,δ))(Δa₀ + 0.6 Δa_Z< 4.8) x 10^-16 GeV, (-7.0 < N(x,y,δ)Δa_x < 3.8) x 10^-16 GeV, and (-7.0 < N(x,y,δ)Δa_y < 3.8) x 10^-16 GeV, where N(x,y,δ) is a normalization factor that incorporates mixing parameters x, y and the doubly Cabibbo suppressed to Cabibbo favored relative strong phase δ.

Assessing Measurement Invariance of the Children's Depression Inventory in Chinese and Italian Primary School Student Samples

Science.gov (United States)

Wu, Wenfeng; Lu, Yongbiao; Tan, Furong; Yao, Shuqiao; Steca, Patrizia; Abela, John R. Z.; Hankin, Benjamin L.

2012-01-01

This study tested the measurement invariance of Children's Depression Inventory (CDI) and compared its factorial variance/covariance and latent means among Chinese and Italian children. Multigroup confirmatory factor analysis of the original five factors identified by Kovacs revealed that full measurement invariance did not hold. Further analysis…

Integrated Advanced Microwave Sounding Unit-A (AMSU-A). Performance Verification Report: Final Comprehensive Performance Test Report, P/N 1331720-2TST, S/N 105/A1

Science.gov (United States)

Platt, R.

1999-01-01

This is the Performance Verification Report, Final Comprehensive Performance Test (CPT) Report, for the Integrated Advanced Microwave Sounding Unit-A (AMSU-A). This specification establishes the requirements for the CPT and Limited Performance Test (LPT) of the AMSU-1A, referred to here in as the unit. The sequence in which the several phases of this test procedure shall take place is shown.

Structural invariance of multiple intelligences, based on the level of execution.

Science.gov (United States)

Almeida, Leandro S; Prieto, María Dolores; Ferreira, Arístides; Ferrando, Mercedes; Ferrandiz, Carmen; Bermejo, Rosario; Hernández, Daniel

2011-11-01

The independence of multiple intelligences (MI) of Gardner's theory has been debated since its conception. This article examines whether the one- factor structure of the MI theory tested in previous studies is invariant for low and high ability students. Two hundred ninety-four children (aged 5 to 7) participated in this study. A set of Gardner's Multiple Intelligence assessment tasks based on the Spectrum Project was used. To analyze the invariance of a general dimension of intelligence, the different models of behaviours were studied in samples of participants with different performance on the Spectrum Project tasks with Multi-Group Confirmatory Factor Analysis (MGCFA). Results suggest an absence of structural invariance in Gardner's tasks. Exploratory analyses suggest a three-factor structure for individuals with higher performance levels and a two-factor structure for individuals with lower performance levels.

Recent progress in invariant pattern recognition

Science.gov (United States)

Arsenault, Henri H.; Chang, S.; Gagne, Philippe; Gualdron Gonzalez, Oscar

1996-12-01

We present some recent results in invariant pattern recognition, including methods that are invariant under two or more distortions of position, orientation and scale. There are now a few methods that yield good results under changes of both rotation and scale. Some new methods are introduced. These include locally adaptive nonlinear matched filters, scale-adapted wavelet transforms and invariant filters for disjoint noise. Methods using neural networks will also be discussed, including an optical method that allows simultaneous classification of multiple targets.

Finite type invariants and fatgraphs

DEFF Research Database (Denmark)

Andersen, Jørgen Ellegaard; Bene, Alex; Meilhan, Jean-Baptiste Odet Thierry

2010-01-01

–Murakami–Ohtsuki of the link invariant of Andersen–Mattes–Reshetikhin computed relative to choices determined by the fatgraph G; this provides a basic connection between 2d geometry and 3d quantum topology. For each fixed G, this invariant is shown to be universal for homology cylinders, i.e., G establishes an isomorphism...

Ermakov–Lewis invariants and Reid systems

Energy Technology Data Exchange (ETDEWEB)

Mancas, Stefan C., E-mail: stefan.mancas@erau.edu [Department of Mathematics, Embry-Riddle Aeronautical University, Daytona Beach, FL 32114-3900 (United States); Rosu, Haret C., E-mail: hcr@ipicyt.edu.mx [IPICyT, Instituto Potosino de Investigacion Cientifica y Tecnologica, Camino a la presa San José 2055, Col. Lomas 4a Sección, 78216 San Luis Potosí, S.L.P. (Mexico)

2014-06-13

Reid's mth-order generalized Ermakov systems of nonlinear coupling constant α are equivalent to an integrable Emden–Fowler equation. The standard Ermakov–Lewis invariant is discussed from this perspective, and a closed formula for the invariant is obtained for the higher-order Reid systems (m≥3). We also discuss the parametric solutions of these systems of equations through the integration of the Emden–Fowler equation and present an example of a dynamical system for which the invariant is equivalent to the total energy. - Highlights: • Reid systems of order m are connected to Emden–Fowler equations. • General expressions for the Ermakov–Lewis invariants both for m=2 and m≥3 are obtained. • Parametric solutions of the Emden–Fowler equations related to Reid systems are obtained.

Factor Structure and Measurement Invariance of the Need-Supportive Teaching Style Scale for Physical Education.

Science.gov (United States)

Liu, Jing-Dong; Chung, Pak-Kwong

2017-08-01

The purpose of the current study was to examine the factor structure and measurement invariance of a scale measuring students' perceptions of need-supportive teaching (Need-Supportive Teaching Style Scale in Physical Education; NSTSSPE). We sampled 615 secondary school students in Hong Kong, 200 of whom also completed a follow-up assessment two months later. Factor structure of the scale was examined through exploratory structural equation modeling (ESEM). Further, nomological validity of the NSTSSPE was evaluated by examining the relationships between need-supportive teaching style and student satisfaction of psychological needs. Finally, four measurement models-configural, metric invariance, scalar invariance, and item uniqueness invariance-were assessed using multiple group ESEM to test the measurement invariance of the scale across gender, grade, and time. ESEM results suggested a three-factor structure of the NSTSSPE. Nomological validity was supported, and weak, strong, and strict measurement invariance of the NSTSSPE was evidenced across gender, grade, and time. The current study provides initial psychometric support for the NSTSSPE to assess student perceptions of teachers' need-supportive teaching style in physical education classes.

Measurement of Job Motivation in TEDS-M: Testing for Invariance across Countries and Cultures

Science.gov (United States)

Laschke, Christin; Blömeke, Sigrid

2016-01-01

The paper presents the challenges of cross-country and cross-cultural research on the motivation to become a mathematics teacher based on data from the "Teacher Education and Development Study in Mathematics" ("TEDS-M"). Referring to studies from cross-cultural psychology, measurement invariance (MI) of constructs representing…

Conformal invariance in the long-range Ising model

Directory of Open Access Journals (Sweden)

Miguel F. Paulos

2016-01-01

Full Text Available We consider the question of conformal invariance of the long-range Ising model at the critical point. The continuum description is given in terms of a nonlocal field theory, and the absence of a stress tensor invalidates all of the standard arguments for the enhancement of scale invariance to conformal invariance. We however show that several correlation functions, computed to second order in the epsilon expansion, are nontrivially consistent with conformal invariance. We proceed to give a proof of conformal invariance to all orders in the epsilon expansion, based on the description of the long-range Ising model as a defect theory in an auxiliary higher-dimensional space. A detailed review of conformal invariance in the d-dimensional short-range Ising model is also included and may be of independent interest.

Conformal Invariance in the Long-Range Ising Model

CERN Document Server

Paulos, Miguel F; van Rees, Balt C; Zan, Bernardo

2016-01-01

We consider the question of conformal invariance of the long-range Ising model at the critical point. The continuum description is given in terms of a nonlocal field theory, and the absence of a stress tensor invalidates all of the standard arguments for the enhancement of scale invariance to conformal invariance. We however show that several correlation functions, computed to second order in the epsilon expansion, are nontrivially consistent with conformal invariance. We proceed to give a proof of conformal invariance to all orders in the epsilon expansion, based on the description of the long-range Ising model as a defect theory in an auxiliary higher-dimensional space. A detailed review of conformal invariance in the d-dimensional short-range Ising model is also included and may be of independent interest.

Conformal invariance in the long-range Ising model

Energy Technology Data Exchange (ETDEWEB)

Paulos, Miguel F. [CERN, Theory Group, Geneva (Switzerland); Rychkov, Slava, E-mail: slava.rychkov@lpt.ens.fr [CERN, Theory Group, Geneva (Switzerland); Laboratoire de Physique Théorique de l' École Normale Supérieure (LPTENS), Paris (France); Faculté de Physique, Université Pierre et Marie Curie (UPMC), Paris (France); Rees, Balt C. van [CERN, Theory Group, Geneva (Switzerland); Zan, Bernardo [Institute of Physics, Universiteit van Amsterdam, Amsterdam (Netherlands)

2016-01-15

We consider the question of conformal invariance of the long-range Ising model at the critical point. The continuum description is given in terms of a nonlocal field theory, and the absence of a stress tensor invalidates all of the standard arguments for the enhancement of scale invariance to conformal invariance. We however show that several correlation functions, computed to second order in the epsilon expansion, are nontrivially consistent with conformal invariance. We proceed to give a proof of conformal invariance to all orders in the epsilon expansion, based on the description of the long-range Ising model as a defect theory in an auxiliary higher-dimensional space. A detailed review of conformal invariance in the d-dimensional short-range Ising model is also included and may be of independent interest.

Personality in general and clinical samples: Measurement invariance of the Multidimensional Personality Questionnaire.

Science.gov (United States)

Eigenhuis, Annemarie; Kamphuis, Jan H; Noordhof, Arjen

2017-09-01

A growing body of research suggests that the same general dimensions can describe normal and pathological personality, but most of the supporting evidence is exploratory. We aim to determine in a confirmatory framework the extent to which responses on the Multidimensional Personality Questionnaire (MPQ) are identical across general and clinical samples. We tested the Dutch brief form of the MPQ (MPQ-BF-NL) for measurement invariance across a general population subsample (N = 365) and a clinical sample (N = 365), using Multiple Group Confirmatory Factor Analysis (MGCFA) and Multiple Group Exploratory Structural Equation Modeling (MGESEM). As an omnibus personality test, the MPQ-BF-NL revealed strict invariance, indicating absence of bias. Unidimensional per scale tests for measurement invariance revealed that 10% of items appeared to contain bias across samples. Item bias only affected the scale interpretation of Achievement, with individuals from the clinical sample more readily admitting to put high demands on themselves than individuals from the general sample, regardless of trait level. This formal test of equivalence provides strong evidence for the common structure of normal and pathological personality and lends further support to the clinical utility of the MPQ. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

BRDF invariant stereo using light transport constancy.

Science.gov (United States)

Wang, Liang; Yang, Ruigang; Davis, James E

2007-09-01

Nearly all existing methods for stereo reconstruction assume that scene reflectance is Lambertian and make use of brightness constancy as a matching invariant. We introduce a new invariant for stereo reconstruction called light transport constancy (LTC), which allows completely arbitrary scene reflectance (bidirectional reflectance distribution functions (BRDFs)). This invariant can be used to formulate a rank constraint on multiview stereo matching when the scene is observed by several lighting configurations in which only the lighting intensity varies. In addition, we show that this multiview constraint can be used with as few as two cameras and two lighting configurations. Unlike previous methods for BRDF invariant stereo, LTC does not require precisely configured or calibrated light sources or calibration objects in the scene. Importantly, the new constraint can be used to provide BRDF invariance to any existing stereo method whenever appropriate lighting variation is available.

Esophageal function testing: Billing and coding update.

Science.gov (United States)

Khan, A; Massey, B; Rao, S; Pandolfino, J

2018-01-01

Esophageal function testing is being increasingly utilized in diagnosis and management of esophageal disorders. There have been several recent technological advances in the field to allow practitioners the ability to more accurately assess and treat such conditions, but there has been a relative lack of education in the literature regarding the associated Common Procedural Terminology (CPT) codes and methods of reimbursement. This review, commissioned and supported by the American Neurogastroenterology and Motility Society Council, aims to summarize each of the CPT codes for esophageal function testing and show the trends of associated reimbursement, as well as recommend coding methods in a practical context. We also aim to encourage many of these codes to be reviewed on a gastrointestinal (GI) societal level, by providing evidence of both discrepancies in coding definitions and inadequate reimbursement in this new era of esophageal function testing. © 2017 John Wiley & Sons Ltd.

A scale invariance criterion for LES parametrizations

Directory of Open Access Journals (Sweden)

Urs Schaefer-Rolffs

2015-01-01

Full Text Available Turbulent kinetic energy cascades in fluid dynamical systems are usually characterized by scale invariance. However, representations of subgrid scales in large eddy simulations do not necessarily fulfill this constraint. So far, scale invariance has been considered in the context of isotropic, incompressible, and three-dimensional turbulence. In the present paper, the theory is extended to compressible flows that obey the hydrostatic approximation, as well as to corresponding subgrid-scale parametrizations. A criterion is presented to check if the symmetries of the governing equations are correctly translated into the equations used in numerical models. By applying scaling transformations to the model equations, relations between the scaling factors are obtained by demanding that the mathematical structure of the equations does not change.The criterion is validated by recovering the breakdown of scale invariance in the classical Smagorinsky model and confirming scale invariance for the Dynamic Smagorinsky Model. The criterion also shows that the compressible continuity equation is intrinsically scale-invariant. The criterion also proves that a scale-invariant turbulent kinetic energy equation or a scale-invariant equation of motion for a passive tracer is obtained only with a dynamic mixing length. For large-scale atmospheric flows governed by the hydrostatic balance the energy cascade is due to horizontal advection and the vertical length scale exhibits a scaling behaviour that is different from that derived for horizontal length scales.

Mild dehydration modifies the cerebrovascular response to the cold pressor test.

Science.gov (United States)

Perry, Blake G; Bear, Tracey L K; Lucas, Samuel J E; Mündel, Toby

2016-01-01

The cold pressor test (CPT) is widely used in clinical practice and physiological research. It is characterized by a robust autonomic response, with associated increases in heart rate (HR), mean arterial pressure (MAP) and mean middle cerebral artery blood flow velocity (MCAv(mean)). Hydration status is not commonly reported when conducting this test, yet blood viscosity alone can modulate MCAv(mean), potentially modifying the MCAv(mean) response to the CPT. We investigated the effect of mild dehydration on the physiological response to the CPT in 10 healthy men (mean ± SD: age 28 ± 5 years; body mass 83 ± 5 kg). All participants completed two CPTs, cold water (0°C) immersion of both feet for 90 s, with the order of the euhydration and dehydration trials counterbalanced. Beat-to-beat MCAv, MAP, HR and breath-by-breath partial pressure of end-tidal CO2 (P(ET,CO2)) were measured continuously. Participants' pain perception was measured 1 min into the CPT using a visual analog scale (no pain = 0; maximal pain = 10). Dehydration significantly elevated plasma osmolality and urine specific gravity and reduced body mass (all P 0.05). After 90 s of immersion, the change in MCAv(mean) from baseline was less in the dehydration compared with the euhydration trial (change 0 ± 5 versus 7 ± 7 cm s(-1), P = 0.01), as was P(ET,CO2) (change -3 ± 2 versus 0 ± 3 mmHg, P = 0.02). Dehydration was associated with greater relative pain sensation during the CPT (7.0 ± 1.3 vs 5.8 ± 1.8, P = 0.02). Our results demonstrate that mild dehydration can modify the cerebrovascular response to the CPT, with dehydration increasing perceived pain, lowering P ET ,CO2 and, ultimately, blunting the MCAv(mean) response. © 2015 The Authors. Experimental Physiology © 2015 The Physiological Society.

New technique for real-time distortion-invariant multiobject recognition and classification

Science.gov (United States)

Hong, Rutong; Li, Xiaoshun; Hong, En; Wang, Zuyi; Wei, Hongan

2001-04-01

A real-time hybrid distortion-invariant OPR system was established to make 3D multiobject distortion-invariant automatic pattern recognition. Wavelet transform technique was used to make digital preprocessing of the input scene, to depress the noisy background and enhance the recognized object. A three-layer backpropagation artificial neural network was used in correlation signal post-processing to perform multiobject distortion-invariant recognition and classification. The C-80 and NOA real-time processing ability and the multithread programming technology were used to perform high speed parallel multitask processing and speed up the post processing rate to ROIs. The reference filter library was constructed for the distortion version of 3D object model images based on the distortion parameter tolerance measuring as rotation, azimuth and scale. The real-time optical correlation recognition testing of this OPR system demonstrates that using the preprocessing, post- processing, the nonlinear algorithm os optimum filtering, RFL construction technique and the multithread programming technology, a high possibility of recognition and recognition rate ere obtained for the real-time multiobject distortion-invariant OPR system. The recognition reliability and rate was improved greatly. These techniques are very useful to automatic target recognition.

Construction of time-dependent dynamical invariants: A new approach

International Nuclear Information System (INIS)

Bertin, M. C.; Pimentel, B. M.; Ramirez, J. A.

2012-01-01

We propose a new way to obtain polynomial dynamical invariants of the classical and quantum time-dependent harmonic oscillator from the equations of motion. We also establish relations between linear and quadratic invariants, and discuss how the quadratic invariant can be related to the Ermakov invariant.

The Tripod School Climate Index: An Invariant Measure of School Safety and Relationships.

Science.gov (United States)

Phillips, Sarah Fierberg; Rowley, Jacob F S

2016-03-01

Recently revised standards for social work practice in schools encourage data-informed school climate interventions that implicitly require invariant measures of school climate. Invariant measures have the same meaning, scale, and origin across different groups of respondents. Although noninvariant measures bias statistical analyses and can lead users to erroneous conclusions, most school climate measures have not been tested for invariance. This study examines the invariance of the Tripod School Climate Index. Exploratory, confirmatory, and multiple-group confirmatory factor analyses were conducted on data collected from 66,531 students across 222 schools. Results indicate that the index is an excellent fit for the data and invariant by student grade level, demographic background, prior achievement, and dropout risk. Results imply that student responses can be validly aggregated to create school-level scores. The index will not bias studies of school climate interventions or bivariate analyses comparing perceptions of school climate across subgroups of students attending the same school. Given the centrality of school climate interventions to social work practice in schools and the consequences of noninvariance, the development of an index with these properties is an important contribution to the field.

Wavelet-based moment invariants for pattern recognition

Science.gov (United States)

Chen, Guangyi; Xie, Wenfang

2011-07-01

Moment invariants have received a lot of attention as features for identification and inspection of two-dimensional shapes. In this paper, two sets of novel moments are proposed by using the auto-correlation of wavelet functions and the dual-tree complex wavelet functions. It is well known that the wavelet transform lacks the property of shift invariance. A little shift in the input signal will cause very different output wavelet coefficients. The autocorrelation of wavelet functions and the dual-tree complex wavelet functions, on the other hand, are shift-invariant, which is very important in pattern recognition. Rotation invariance is the major concern in this paper, while translation invariance and scale invariance can be achieved by standard normalization techniques. The Gaussian white noise is added to the noise-free images and the noise levels vary with different signal-to-noise ratios. Experimental results conducted in this paper show that the proposed wavelet-based moments outperform Zernike's moments and the Fourier-wavelet descriptor for pattern recognition under different rotation angles and different noise levels. It can be seen that the proposed wavelet-based moments can do an excellent job even when the noise levels are very high.

Novel topological invariants and anomalies

International Nuclear Information System (INIS)

Hirayama, M.; Sugimasa, N.

1987-01-01

It is shown that novel topological invariants are associated with a class of Dirac operators. Trace formulas which are similar to but different from Callias's formula are derived. Implications of these topological invariants to anomalies in quantum field theory are discussed. A new class of anomalies are calculated for two models: one is two dimensional and the other four dimensional

Wilson loop invariants from WN conformal blocks

Directory of Open Access Journals (Sweden)

Oleg Alekseev

2015-12-01

Full Text Available Knot and link polynomials are topological invariants calculated from the expectation value of loop operators in topological field theories. In 3D Chern–Simons theory, these invariants can be found from crossing and braiding matrices of four-point conformal blocks of the boundary 2D CFT. We calculate crossing and braiding matrices for WN conformal blocks with one component in the fundamental representation and another component in a rectangular representation of SU(N, which can be used to obtain HOMFLY knot and link invariants for these cases. We also discuss how our approach can be generalized to invariants in higher-representations of WN algebra.

Maxwell-Chern-Simons vortices in a CPT-odd Lorentz-violating Higgs electrodynamics

International Nuclear Information System (INIS)

Casana, R.; Ferreira, M.M.; Hora, E. da; Neves, A.B.F.

2014-01-01

We study BPS vortices in a CPT-odd and Lorentz-violating Maxwell-Chern-Simons-Higgs (MCSH) electrodynamics attained from the dimensional reduction of the Carroll-Field-Jackiw-Higgs model. The Lorentz-violating parameter induces a pronounced behavior at origin (for the magnetic/electric fields and energy density) which is absent in the MCSH vortices. For some combination of the Lorentz-violating coefficients there always exists a sufficiently large winding number n 0 such that for all vertical stroke n vertical stroke ≥ vertical stroke n 0 vertical stroke the magnetic field flips sign, yielding two well-defined regions with opposite magnetic flux. However, the total magnetic flux remains quantized and proportional to the winding number. (orig.)

Invariants of triangular Lie algebras

International Nuclear Information System (INIS)

Boyko, Vyacheslav; Patera, Jiri; Popovych, Roman

2007-01-01

Triangular Lie algebras are the Lie algebras which can be faithfully represented by triangular matrices of any finite size over the real/complex number field. In the paper invariants ('generalized Casimir operators') are found for three classes of Lie algebras, namely those which are either strictly or non-strictly triangular, and for so-called special upper triangular Lie algebras. Algebraic algorithm of Boyko et al (2006 J. Phys. A: Math. Gen.39 5749 (Preprint math-ph/0602046)), developed further in Boyko et al (2007 J. Phys. A: Math. Theor.40 113 (Preprint math-ph/0606045)), is used to determine the invariants. A conjecture of Tremblay and Winternitz (2001 J. Phys. A: Math. Gen.34 9085), concerning the number of independent invariants and their form, is corroborated

Measurement Invariance Testing of a Three-Factor Model of Parental Warmth, Psychological Control, and Knowledge across European and Asian/Pacific Islander American Youth.

Science.gov (United States)

Luk, Jeremy W; King, Kevin M; McCarty, Carolyn A; Stoep, Ann Vander; McCauley, Elizabeth

2016-06-01

While the interpretation and effects of parenting on developmental outcomes may be different across European and Asian/Pacific Islander (API) American youth, measurement invariance of parenting constructs has rarely been examined. Utilizing multiple-group confirmatory factor analysis, we examined whether the latent structure of parenting measures are equivalent or different across European and API American youth. Perceived parental warmth, psychological control, and knowledge were reported by a community sample of 325 adolescents (242 Europeans and 83 APIs). Results indicated that one item did not load on mother psychological control for API American youth. After removing this item, we found metric invariance for all parenting dimensions, providing support for cross-cultural consistency in the interpretation of parenting items. Scalar invariance was found for father parenting, whereas three mother parenting items were non-invariant across groups at the scalar level. After taking into account several minor forms of measurement non-invariance, non-invariant factor means suggested that API Americans perceived lower parental warmth and knowledge but higher parental psychological control than European Americans. Overall, the degree of measurement non-invariance was not extensive and was primarily driven by a few parenting items. All but one parenting item included in this study may be used for future studies across European and API American youth.

Transformation-invariant and nonparametric monotone smooth estimation of ROC curves.

Science.gov (United States)

Du, Pang; Tang, Liansheng

2009-01-30

When a new diagnostic test is developed, it is of interest to evaluate its accuracy in distinguishing diseased subjects from non-diseased subjects. The accuracy of the test is often evaluated by receiver operating characteristic (ROC) curves. Smooth ROC estimates are often preferable for continuous test results when the underlying ROC curves are in fact continuous. Nonparametric and parametric methods have been proposed by various authors to obtain smooth ROC curve estimates. However, there are certain drawbacks with the existing methods. Parametric methods need specific model assumptions. Nonparametric methods do not always satisfy the inherent properties of the ROC curves, such as monotonicity and transformation invariance. In this paper we propose a monotone spline approach to obtain smooth monotone ROC curves. Our method ensures important inherent properties of the underlying ROC curves, which include monotonicity, transformation invariance, and boundary constraints. We compare the finite sample performance of the newly proposed ROC method with other ROC smoothing methods in large-scale simulation studies. We illustrate our method through a real life example. Copyright (c) 2008 John Wiley & Sons, Ltd.

Action priors for learning domain invariances

CSIR Research Space (South Africa)

Rosman, Benjamin S

2015-04-01

Full Text Available behavioural invariances in the domain, by identifying actions to be prioritised in local contexts, invariant to task details. This information has the effect of greatly increasing the speed of solving new problems. We formalise this notion as action priors...

Maxwell equations in conformal invariant electrodynamics

International Nuclear Information System (INIS)

Fradkin, E.S.; AN SSSR, Novosibirsk. Inst. Avtomatiki i Ehlektrometrii); Kozhevnikov, A.A.; Palchik, M.Ya.; Pomeransky, A.A.

1983-01-01

We consider a conformal invariant formulation of quantum electrodynamics. Conformal invariance is achieved with a specific mathematical construction based on the indecomposable representations of the conformal group associated with the electromagnetic potential and current. As a corolary of this construction modified expressions for the 3-point Green functions are obtained which both contain transverse parts. They make it possible to formulate a conformal invariant skeleton perturbation theory. It is also shown that the Euclidean Maxwell equations in conformal electrodynamics are manifestations of its kinematical structure: in the case of the 3-point Green functions these equations follow (up to constants) from the conformal invariance while in the case of higher Green functions they are equivalent to the equality of the kernels of the partial wave expansions. This is the manifestation of the mathematical fast of a (partial) equivalence of the representations associated with the potential, current and the field tensor. (orig.)

HONTIOR - HIGHER-ORDER NEURAL NETWORK FOR TRANSFORMATION INVARIANT OBJECT RECOGNITION

Science.gov (United States)

Spirkovska, L.

1994-01-01

Neural networks have been applied in numerous fields, including transformation invariant object recognition, wherein an object is recognized despite changes in the object's position in the input field, size, or rotation. One of the more successful neural network methods used in invariant object recognition is the higher-order neural network (HONN) method. With a HONN, known relationships are exploited and the desired invariances are built directly into the architecture of the network, eliminating the need for the network to learn invariance to transformations. This results in a significant reduction in the training time required, since the network needs to be trained on only one view of each object, not on numerous transformed views. Moreover, one hundred percent accuracy is guaranteed for images characterized by the built-in distortions, providing noise is not introduced through pixelation. The program HONTIOR implements a third-order neural network having invariance to translation, scale, and in-plane rotation built directly into the architecture, Thus, for 2-D transformation invariance, the network needs only to be trained on just one view of each object. HONTIOR can also be used for 3-D transformation invariant object recognition by training the network only on a set of out-of-plane rotated views. Historically, the major drawback of HONNs has been that the size of the input field was limited to the memory required for the large number of interconnections in a fully connected network. HONTIOR solves this problem by coarse coding the input images (coding an image as a set of overlapping but offset coarser images). Using this scheme, large input fields (4096 x 4096 pixels) can easily be represented using very little virtual memory (30Mb). The HONTIOR distribution consists of three main programs. The first program contains the training and testing routines for a third-order neural network. The second program contains the same training and testing procedures as the

Brain Oscillations Elicited by the Cold Pressor Test: A Putative Index of Untreated Essential Hypertension

Directory of Open Access Journals (Sweden)

Christos Papageorgiou

2017-01-01

Full Text Available Objective. Essential hypertension is associated with reduced pain sensitivity of unclear aetiology. This study explores this issue using the Cold Pressor Test (CPT, a reliable pain/stress model, comparing CPT-related EEG activity in first episode hypertensives and controls. Method. 22 untreated hypertensives and 18 matched normotensives underwent 24-hour ambulatory blood pressure monitoring (ABPM. EEG recordings were taken before, during, and after CPT exposure. Results. Significant group differences in CPT-induced EEG oscillations were covaried with the most robust cardiovascular differentiators by means of a Canonical Analysis. Positive correlations were noted between ABPM variables and Delta (1–4 Hz oscillations during the tolerance phase; in high-alpha (10–12 Hz oscillations during the stress unit and posttest phase; and in low-alpha (8–10 Hz oscillations during CPT phases overall. Negative correlations were found between ABPM variables and Beta2 oscillations (16.5–20 Hz during the posttest phase and Gamma (28.5–45 Hz oscillations during the CPT phases overall. These relationships were localised at several sites across the cerebral hemispheres with predominance in the right hemisphere and left frontal lobe. Conclusions. These findings provide a starting point for increasing our understanding of the complex relationships between cerebral activation and cardiovascular functioning involved in regulating blood pressure changes.

Experimental study of time-reversal invariance in neutron-nucleus interactions

International Nuclear Information System (INIS)

Shaparov, E.I.; Shimizu, H.M.

1996-01-01

Experimental approaches for the test of time-reversal invariance in neutron-nucleus interactions are reviewed. Possible transmission experiments with polarized neutron beams and polarized or aligned targets are discussed as well as neutron capture experiments with unpolarized resonance neutrons. 102 refs., 13 figs., 3 tabs

Embedded graph invariants in Chern-Simons theory

International Nuclear Information System (INIS)

Major, Seth A.

1999-01-01

Chern-Simons gauge theory, since its inception as a topological quantum field theory, has proved to be a rich source of understanding for knot invariants. In this work the theory is used to explore the definition of the expectation value of a network of Wilson lines -- an embedded graph invariant. Using a generalization of the variational method, lowest-order results for invariants for graphs of arbitrary valence and general vertex tangent space structure are derived. Gauge invariant operators are introduced. Higher order results are found. The method used here provides a Vassiliev-type definition of graph invariants which depend on both the embedding of the graph and the group structure of the gauge theory. It is found that one need not frame individual vertices. However, without a global projection of the graph there is an ambiguity in the relation of the decomposition of distinct vertices. It is suggested that framing may be seen as arising from this ambiguity -- as a way of relating frames at distinct vertices

Relating measurement invariance, cross-level invariance, and multilevel reliability

NARCIS (Netherlands)

Jak, S.; Jorgensen, T.D.

2017-01-01

Data often have a nested, multilevel structure, for example when data are collected from children in classrooms. This kind of data complicate the evaluation of reliability and measurement invariance, because several properties can be evaluated at both the individual level and the cluster level, as

Conformal invariance and two-dimensional physics

International Nuclear Information System (INIS)

Zuber, J.B.

1993-01-01

Actually, physicists and mathematicians are very interested in conformal invariance: geometric transformations which keep angles. This symmetry is very important for two-dimensional systems as phase transitions, string theory or node mathematics. In this article, the author presents the conformal invariance and explains its usefulness

Pattern recognition: invariants in 3D

International Nuclear Information System (INIS)

Proriol, J.

1992-01-01

In e + e - events, the jets have a spherical 3D symmetry. A set of invariants are defined for 3D objects with a spherical symmetry. These new invariants are used to tag the number of jets in e + e - events. (K.A.) 3 refs

A scale invariant covariance structure on jet space

DEFF Research Database (Denmark)

Pedersen, Kim Steenstrup; Loog, Marco; Markussen, Bo

2005-01-01

This paper considers scale invariance of statistical image models. We study statistical scale invariance of the covariance structure of jet space under scale space blurring and derive the necessary structure and conditions of the jet covariance matrix in order for it to be scale invariant. As par...

Inflation in a Scale Invariant Universe

Energy Technology Data Exchange (ETDEWEB)

Ferreira, Pedro G. [Oxford U.; Hill, Christopher T. [Fermilab; Noller, Johannes [Zurich U.; Ross, Graham G. [Oxford U., Theor. Phys.

2018-02-16

A scale-invariant universe can have a period of accelerated expansion at early times: inflation. We use a frame-invariant approach to calculate inflationary observables in a scale invariant theory of gravity involving two scalar fields - the spectral indices, the tensor to scalar ratio, the level of isocurvature modes and non-Gaussianity. We show that scale symmetry leads to an exact cancellation of isocurvature modes and that, in the scale-symmetry broken phase, this theory is well described by a single scalar field theory. We find the predictions of this theory strongly compatible with current observations.

Gromov-Witten invariants and localization

Science.gov (United States)

Morrison, David R.

2017-11-01

We give a pedagogical review of the computation of Gromov-Witten invariants via localization in 2D gauged linear sigma models. We explain the relationship between the two-sphere partition function of the theory and the Kähler potential on the conformal manifold. We show how the Kähler potential can be assembled from classical, perturbative, and non-perturbative contributions, and explain how the non-perturbative contributions are related to the Gromov-Witten invariants of the corresponding Calabi-Yau manifold. We then explain how localization enables efficient calculation of the two-sphere partition function and, ultimately, the Gromov-Witten invariants themselves. This is a contribution to the review issue ‘Localization techniques in quantum field theories’ (ed V Pestun and M Zabzine) which contains 17 chapters, available at [1].

The visual system supports online translation invariance for object identification.

Science.gov (United States)

Bowers, Jeffrey S; Vankov, Ivan I; Ludwig, Casimir J H

2016-04-01

The ability to recognize the same image projected to different retinal locations is critical for visual object recognition in natural contexts. According to many theories, the translation invariance for objects extends only to trained retinal locations, so that a familiar object projected to a nontrained location should not be identified. In another approach, invariance is achieved "online," such that learning to identify an object in one location immediately affords generalization to other locations. We trained participants to name novel objects at one retinal location using eyetracking technology and then tested their ability to name the same images presented at novel retinal locations. Across three experiments, we found robust generalization. These findings provide a strong constraint for theories of vision.

Affine invariants of convex polygons.

Science.gov (United States)

Flusser, Jan

2002-01-01

In this correspondence, we prove that the affine invariants, for image registration and object recognition, proposed recently by Yang and Cohen (see ibid., vol.8, no.7, p.934-46, July 1999) are algebraically dependent. We show how to select an independent and complete set of the invariants. The use of this new set leads to a significant reduction of the computing complexity without decreasing the discrimination power.

Notes on algebraic invariants for non-commutative dynamical systems

Energy Technology Data Exchange (ETDEWEB)

Longo, R [Rome Univ. (Italy). Istituto di Matematica

1979-11-01

We consider an algebraic invariant for non-commutative dynamical systems naturally arising as the spectrum of the modular operator associated to an invariant state, provided certain conditions of mixing type are present. This invariant turns out to be exactly the annihilator of the invariant T of Connes. Further comments are included, in particular on the type of certain algebras of local observables

Newton gauge cosmological perturbations for static spherically symmetric modifications of the de Sitter metric

Science.gov (United States)

Santa Vélez, Camilo; Enea Romano, Antonio

2018-05-01

Static coordinates can be convenient to solve the vacuum Einstein's equations in presence of spherical symmetry, but for cosmological applications comoving coordinates are more suitable to describe an expanding Universe, especially in the framework of cosmological perturbation theory (CPT). Using CPT we develop a method to transform static spherically symmetric (SSS) modifications of the de Sitter solution from static coordinates to the Newton gauge. We test the method with the Schwarzschild de Sitter (SDS) metric and then derive general expressions for the Bardeen's potentials for a class of SSS metrics obtained by adding to the de Sitter metric a term linear in the mass and proportional to a general function of the radius. Using the gauge invariance of the Bardeen's potentials we then obtain a gauge invariant definition of the turn around radius. We apply the method to an SSS solution of the Brans-Dicke theory, confirming the results obtained independently by solving the perturbation equations in the Newton gauge. The Bardeen's potentials are then derived for new SSS metrics involving logarithmic, power law and exponential modifications of the de Sitter metric. We also apply the method to SSS metrics which give flat rotation curves, computing the radial energy density profile in comoving coordinates in presence of a cosmological constant.

Conformal invariance in supergravity

International Nuclear Information System (INIS)

Bergshoeff, E.A.

1983-01-01

In this thesis the author explains the role of conformal invariance in supergravity. He presents the complete structure of extended conformal supergravity for N <= 4. The outline of this work is as follows. In chapter 2 he briefly summarizes the essential properties of supersymmetry and supergravity and indicates the use of conformal invariance in supergravity. The idea that the introduction of additional symmetry transformations can make clear the structure of a field theory is not reserved to supergravity only. By means of some simple examples it is shown in chapter 3 how one can always introduce additional gauge transformations in a theory of massive vector fields. Moreover it is shown how the gauge invariant formulation sometimes explains the quantum mechanical properties of the theory. In chapter 4 the author defines the conformal transformations and summarizes their main properties. He explains how these conformal transformations can be used to analyse the structure of gravity. The supersymmetric extension of these results is discussed in chapter 5. Here he describes as an example how N=1 supergravity can be reformulated in a conformally-invariant way. He also shows that beyond N=1 the gauge fields of the superconformal symmetries do not constitute an off-shell field representation of extended conformal supergravity. Therefore, in chapter 6, a systematic method to construct the off-shell formulation of all extended conformal supergravity theories with N <= 4 is developed. As an example he uses this method to construct N=1 conformal supergravity. Finally, in chapter 7 N=4 conformal supergravity is discussed. (Auth.)

Spacetime-varying couplings and Lorentz violation

International Nuclear Information System (INIS)

Kostelecky, V. Alan; Lehnert, Ralf; Perry, Malcolm J.

2003-01-01

Spacetime-varying coupling constants can be associated with violations of local Lorentz invariance and CPT symmetry. An analytical supergravity cosmology with a time-varying fine-structure constant provides an explicit example. Estimates are made for some experimental constraints

Quantum tunneling, adiabatic invariance and black hole spectroscopy

Science.gov (United States)

Li, Guo-Ping; Pu, Jin; Jiang, Qing-Quan; Zu, Xiao-Tao

2017-05-01

In the tunneling framework, one of us, Jiang, together with Han has studied the black hole spectroscopy via adiabatic invariance, where the adiabatic invariant quantity has been intriguingly obtained by investigating the oscillating velocity of the black hole horizon. In this paper, we attempt to improve Jiang-Han's proposal in two ways. Firstly, we once again examine the fact that, in different types (Schwarzschild and Painlevé) of coordinates as well as in different gravity frames, the adiabatic invariant I_adia = \\oint p_i dq_i introduced by Jiang and Han is canonically invariant. Secondly, we attempt to confirm Jiang-Han's proposal reasonably in more general gravity frames (including Einstein's gravity, EGB gravity and HL gravity). Concurrently, for improving this proposal, we interestingly find in more general gravity theories that the entropy of the black hole is an adiabatic invariant action variable, but the horizon area is only an adiabatic invariant. In this sense, we emphasize the concept that the quantum of the black hole entropy is more natural than that of the horizon area.

Object recognition by implicit invariants

Czech Academy of Sciences Publication Activity Database

Flusser, Jan; Kautsky, J.; Šroubek, Filip

2007-01-01

Roč. 2007, č. 4673 (2007), s. 856-863 ISSN 0302-9743. [Computer Analysis of Images and Patterns. Vienna, 27.08.2007-29.08.2007] R&D Projects: GA MŠk 1M0572 Institutional research plan: CEZ:AV0Z10750506 Keywords : Invariants * implicit invariants * moments * orthogonal polynomials * nonlinear object deformation Subject RIV: JD - Computer Applications, Robotics Impact factor: 0.402, year: 2005 http:// staff .utia.cas.cz/sroubekf/papers/CAIP_07.pdf

In-Pipe Wireless Communication for Underground Sampling and Testing

NARCIS (Netherlands)

Nguyen, Nhan D.T.; Le, Duc V.; Meratnia, Nirvana; Havinga, Paul J.M.

2017-01-01

In this paper, we present an effective and low- cost wireless communication system for extremely long and narrow pipes that can replay the extant wire system in underground sensor network applications such as soil sampling and testing with the Cone Penetration Test (CPT), the most widely used

Modular invariance, chiral anomalies and contact terms

International Nuclear Information System (INIS)

Kutasov, D.

1988-03-01

The chiral anomaly in heterotic strings with full and partial modular invariance in D=2n+2 dimensions is calculated. The boundary terms which were present in previous calculations are shown to be cancelled in the modular invariant case by contact terms, which can be obtained by an appropriate analytic continuation. The relation to the low energy field theory is explained. In theories with partial modular invariance, an expression for the anomaly is obtained and shown to be non zero in general. (author)

Cross-Cultural Invariance of the Mental Toughness Inventory Among Australian, Chinese, and Malaysian Athletes: A Bayesian Estimation Approach.

Science.gov (United States)

Gucciardi, Daniel F; Zhang, Chun-Qing; Ponnusamy, Vellapandian; Si, Gangyan; Stenling, Andreas

2016-04-01

The aims of this study were to assess the cross-cultural invariance of athletes' self-reports of mental toughness and to introduce and illustrate the application of approximate measurement invariance using Bayesian estimation for sport and exercise psychology scholars. Athletes from Australia (n = 353, Mage = 19.13, SD = 3.27, men = 161), China (n = 254, Mage = 17.82, SD = 2.28, men = 138), and Malaysia (n = 341, Mage = 19.13, SD = 3.27, men = 200) provided a cross-sectional snapshot of their mental toughness. The cross-cultural invariance of the mental toughness inventory in terms of (a) the factor structure (configural invariance), (b) factor loadings (metric invariance), and (c) item intercepts (scalar invariance) was tested using an approximate measurement framework with Bayesian estimation. Results indicated that approximate metric and scalar invariance was established. From a methodological standpoint, this study demonstrated the usefulness and flexibility of Bayesian estimation for single-sample and multigroup analyses of measurement instruments. Substantively, the current findings suggest that the measurement of mental toughness requires cultural adjustments to better capture the contextually salient (emic) aspects of this concept.

Strong coupling in a gauge invariant field theory

Energy Technology Data Exchange (ETDEWEB)

Johnson, K. [Physics Department, Massachusetts Institute of Technology, Cambridge, MA (United States)

1963-01-15

I would like to discuss some approximations which may be significant in the domain of strong coupling in a field system analogous to quantum electrodynamics. The motivation of this work is the idea that the strong couplings and elementary particle spectrum may be the consequence of the dynamics of a system whose underlying description is in terms of a set of Fermi fields gauge invariantly coupled to a single (''bare'') massless neutral vector field. The basis of this gauge invariance would of course be the exact conservation law of baryons or ''nucleonic charge''. It seems to me that a coupling scheme based on an invariance principle is most attractive if that invariance is an exact one. It would then be nice to try to account for the approximate invariance principles in the same way one would describe ''accidental degeneracies'' in any quantum system.

Quantum Hall Conductivity and Topological Invariants

Science.gov (United States)

Reyes, Andres

2001-04-01

A short survey of the theory of the Quantum Hall effect is given emphasizing topological aspects of the quantization of the conductivity and showing how topological invariants can be derived from the hamiltonian. We express these invariants in terms of Chern numbers and show in precise mathematical terms how this relates to the Kubo formula.

Quantized gauge invariant periodic TDHF solutions

International Nuclear Information System (INIS)

Kan, K.-K.; Griffin, J.J.; Lichtner, P.C.; Dworzecka, M.

1979-01-01

Time-dependent Hartree-Fock (TDHF) is used to study steady state large amplitude nuclear collective motions, such as vibration and rotation. As is well known the small amplitude TDHF leads to the RPA equation. The analysis of periodicity in TDHF is not trivial because TDHF is a nonlinear theory and it is not known under what circumstances a nonlinear theory can support periodic solutions. It is also unknown whether such periodic solution, if they exist, form a continuous or a discrete set. But, these properties may be important in obtaining the energy spectrum of the collective states from the TDHF description. The periodicity and Gauge Invariant Periodicity of solutions are investigated for that class of models whose TDHF solutions depend on time through two parameters. In such models TDHF supports a continuous family of periodic solutions, but only a discrete subset of these is gauge invariant. These discrete Gauge Invariant Periodic solutions obey the Bohr-Summerfeld quantization rule. The energy spectrum of the Gauge Invariant Periodic solutions is compared with the exact eigenergies in one specific example

Classification of simple current invariants

CERN Document Server

Gato-Rivera, Beatriz

1992-01-01

We summarize recent work on the classification of modular invariant partition functions that can be obtained with simple currents in theories with a center (Z_p)^k with p prime. New empirical results for other centers are also presented. Our observation that the total number of invariants is monodromy-independent for (Z_p)^k appears to be true in general as well. (Talk presented in the parallel session on string theory of the Lepton-Photon/EPS Conference, Geneva, 1991.)

Association between genetic variants of the ADD1 and GNB3 genes and blood pressure response to the cold pressor test in a Chinese Han population: the GenSalt Study.

Science.gov (United States)

Wang, Laiyuan; Chen, Shufeng; Zhao, Qi; Hixson, James E; Rao, Dabeeru C; Jaquish, Cashell E; Huang, Jianfeng; Lu, Xiangfeng; Chen, Jichun; Cao, Jie; Li, Jianxin; Li, Hongfan; He, Jiang; Liu, De-Pei; Gu, Dongfeng

2012-08-01

Genetic factors influence blood pressure (BP) response to the cold pressor test (CPT), which is a phenotype related to hypertension risk. We examined the association between variants of the α-adducin (ADD1) and guanine nucleotide binding protein (G protein) β-polypeptide 3 (GNB3) genes and BP response to the CPT. A total of 1998 Han Chinese participants from the Genetic Epidemiology Network of Salt Sensitivity completed the CPT. The area under the curve (AUC) above the baseline BP during the CPT was used to measure the BP response. Twelve single-nucleotide polymorphisms (SNPs) of the ADD1 and GNB3 genes were selected and genotyped. Both single-marker and haplotype association analyses were conducted using linear mixed models. The rs17833172 and rs3775067 SNPs of the ADD1 gene and the rs4963516 SNP of the GNB3 gene were significantly associated with the BP response to CPT, even after adjusting for multiple testing. For the ADD1 gene, the AA genotype of SNP rs17833172 was associated with lower systolic BP (SBP) reactivity (PAUC (P=0.003). Haplotype analysis indicated that the CCGC haplotype of ADD1 constructed by rs1263359, rs3775067, rs4961 and rs4963 was significantly associated with the BP response to CPT. These data suggest that genetic variants of the ADD1 and GNB3 genes may have important roles in BP response to the CPT. Future studies aimed at replicating these novel findings are warranted.

Holography beyond conformal invariance and AdS isometry?

CERN Document Server

Barvinsky, A.O.

2015-01-01

We suggest that the principle of holographic duality can be extended beyond conformal invariance and AdS isometry. Such an extension is based on a special relation between functional determinants of the operators acting in the bulk and on its boundary, provided that the boundary operator represents the inverse propagators of the theory induced on the boundary by the Dirichlet boundary value problem from the bulk spacetime. This relation holds for operators of general spin-tensor structure on generic manifolds with boundaries irrespective of their background geometry and conformal invariance, and it apparently underlies numerous $O(N^0)$ tests of AdS/CFT correspondence, based on direct calculation of the bulk and boundary partition functions, Casimir energies and conformal anomalies. The generalized holographic duality is discussed within the concept of the "double-trace" deformation of the boundary theory, which is responsible in the case of large $N$ CFT coupled to the tower of higher spin gauge fields for t...

The utility of quantitative electroencephalography and Integrated Visual and Auditory Continuous Performance Test as auxiliary tools for the Attention Deficit Hyperactivity Disorder diagnosis.

Science.gov (United States)

Kim, JunWon; Lee, YoungSik; Han, DougHyun; Min, KyungJoon; Kim, DoHyun; Lee, ChangWon

2015-03-01

This study investigated the clinical utility of quantitative electroencephalography (QEEG) and the Integrated Visual and Auditory Continuous Performance Test (IVA+CPT) as auxiliary tools for assessing Attention Deficit Hyperactivity Disorder (ADHD). All of 157 subjects were assessed using the Korean version of the Diagnostic Interview Schedule for Children Version IV (DISC-IV). We measured EGG absolute power in 21 channels and conducted IVA+CPT. We analyzed QEEG according to the Hz range: delta (1-4Hz), theta (4-8Hz), slow alpha (8-10Hz), fast alpha (10-13.5Hz), and beta (13.5-30Hz). To remove artifacts, independent component analysis was conducted (ICA), and the tester confirmed the results again. All of the IVA+CPT quotients showed significant differences between the ADHD and control groups. The ADHD group showed significantly increased delta and theta activity compared with the control group. The z-scores of theta were negatively correlated with the scores of IVA+CPT in ADHD combined type, and those of beta were positively correlated. IVA+CPT and QEEG significantly discriminated between ADHD and control groups. The commission error of IVA+CPT showed an accuracy of 82.1%, and the omission error of IVA+CPT showed an accuracy of 78.6%. The IVA+CPT and QEEG are expected to be valuable tools for aiding ADHD diagnosis accurately. Copyright © 2014 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.

Computation of Quasiperiodic Normally Hyperbolic Invariant Tori: Rigorous Results

Science.gov (United States)

Canadell, Marta; Haro, Àlex

2017-12-01

The development of efficient methods for detecting quasiperiodic oscillations and computing the corresponding invariant tori is a subject of great importance in dynamical systems and their applications in science and engineering. In this paper, we prove the convergence of a new Newton-like method for computing quasiperiodic normally hyperbolic invariant tori carrying quasiperiodic motion in smooth families of real-analytic dynamical systems. The main result is stated as an a posteriori KAM-like theorem that allows controlling the inner dynamics on the torus with appropriate detuning parameters, in order to obtain a prescribed quasiperiodic motion. The Newton-like method leads to several fast and efficient computational algorithms, which are discussed and tested in a companion paper (Canadell and Haro in J Nonlinear Sci, 2017. doi: 10.1007/s00332-017-9388-z), in which new mechanisms of breakdown are presented.

Testing Lorentz Invariance Emergence in the Ising Model using Monte Carlo simulations

CERN Document Server

Dias Astros, Maria Isabel

2017-01-01

In the context of the Lorentz invariance as an emergent phenomenon at low energy scales to study quantum gravity a system composed by two 3D interacting Ising models (one with an anisotropy in one direction) was proposed. Two Monte Carlo simulations were run: one for the 2D Ising model and one for the target model. In both cases the observables (energy, magnetization, heat capacity and magnetic susceptibility) were computed for different lattice sizes and a Binder cumulant introduced in order to estimate the critical temperature of the systems. Moreover, the correlation function was calculated for the 2D Ising model.

Quantum tunneling, adiabatic invariance and black hole spectroscopy

Energy Technology Data Exchange (ETDEWEB)

Li, Guo-Ping; Zu, Xiao-Tao [University of Electronic Science and Technology of China, School of Physical Electronics, Chengdu (China); Pu, Jin [University of Electronic Science and Technology of China, School of Physical Electronics, Chengdu (China); China West Normal University, College of Physics and Space Science, Nanchong (China); Jiang, Qing-Quan [China West Normal University, College of Physics and Space Science, Nanchong (China)

2017-05-15

In the tunneling framework, one of us, Jiang, together with Han has studied the black hole spectroscopy via adiabatic invariance, where the adiabatic invariant quantity has been intriguingly obtained by investigating the oscillating velocity of the black hole horizon. In this paper, we attempt to improve Jiang-Han's proposal in two ways. Firstly, we once again examine the fact that, in different types (Schwarzschild and Painleve) of coordinates as well as in different gravity frames, the adiabatic invariant I{sub adia} = circular integral p{sub i}dq{sub i} introduced by Jiang and Han is canonically invariant. Secondly, we attempt to confirm Jiang-Han's proposal reasonably in more general gravity frames (including Einstein's gravity, EGB gravity and HL gravity). Concurrently, for improving this proposal, we interestingly find in more general gravity theories that the entropy of the black hole is an adiabatic invariant action variable, but the horizon area is only an adiabatic invariant. In this sense, we emphasize the concept that the quantum of the black hole entropy is more natural than that of the horizon area. (orig.)

Tests of Lorentz violation in νμ→νe oscillations

International Nuclear Information System (INIS)

Auerbach, L.B.; Burman, R.L.; Donahue, J.B.; Garvey, G.T.; Louis, W.C.; Mills, G.B.; Sandberg, V.D.; White, D.H.; Caldwell, D.O.; Yellin, S.; Church, E.D.; McIlhany, K.L.; Strossman, W.H.; Cochran, A.K.; Fazely, A.R.; Gunasingha, R.; Imlay, R.L.; Metcalf, W.J.; Sung, M.; Katori, T.

2005-01-01

A recently developed standard-model extension (SME) formalism for neutrino oscillations that includes Lorentz and CPT violation is used to analyze the sidereal time variation of the neutrino event excess measured by the liquid scintillator neutrino detector (LSND) experiment. The LSND experiment, performed at Los Alamos National Laboratory, observed an excess, consistent with neutrino oscillations, of ν e in a beam of ν μ . It is determined that the LSND oscillation signal is consistent with no sidereal variation. However, there are several combinations of SME coefficients that describe the LSND data; both with and without sidereal variations. The scale of Lorentz and CPT violation extracted from the LSND data is of order 10 -19 GeV for the SME coefficients a L and Exc L . This solution for Lorentz and CPT violating neutrino oscillations may be tested by other short baseline neutrino oscillation experiments, such as the MiniBooNE experiment

CP violation in b → s penguin decays and T, CPT violation at BaBar and BELLE

International Nuclear Information System (INIS)

Emery-Schrenk, S.

2014-01-01

We report on the first direct observation of time reversal violation at BABAR in the interference between direct decay and decay with B 0 - B-bar 0 mixing, as well as on the most precise search for CPT violation in B 0 - B-bar 0 mixing at BELLE. We then present recent CP violation studies at BABAR in rare b → s penguin decays B → KKK and B → K*l + l - . (author)

The Influence of Methylphenidate on Hyperactivity and Attention Deficits in Children With ADHD. A Virtual Classroom Test

OpenAIRE

Mühlberger, Andreas; Jekel, K.; Probst, Thomas; Schecklmann, Martin

2016-01-01

Objective: This study compares the performance in a continuous performance test within a virtual reality classroom (CPT-VRC) between medicated children with ADHD, unmedicated children with ADHD, and healthy children. Method: N = 94 children with ADHD (n = 26 of them received methylphenidate and n = 68 were unmedicated) and n = 34 healthy children performed the CPT-VRC. Omission errors, reaction time/variability, commission errors, and body movements were assessed. Furthermore, ADHD...

Cerebral networks of sustained attention and working memory: a functional magnetic resonance imaging study based on the Continuous Performance Test.

Science.gov (United States)

Bartés-Serrallonga, M; Adan, A; Solé-Casals, J; Caldú, X; Falcón, C; Pérez-Pàmies, M; Bargalló, N; Serra-Grabulosa, J M

2014-04-01

One of the most used paradigms in the study of attention is the Continuous Performance Test (CPT). The identical pairs version (CPT-IP) has been widely used to evaluate attention deficits in developmental, neurological and psychiatric disorders. However, the specific locations and the relative distribution of brain activation in networks identified with functional imaging, varies significantly with differences in task design. To design a task to evaluate sustained attention using functional magnetic resonance imaging (fMRI), and thus to provide data for research concerned with the role of these functions. Forty right-handed, healthy students (50% women; age range: 18-25 years) were recruited. A CPT-IP implemented as a block design was used to assess sustained attention during the fMRI session. The behavioural results from the CPT-IP task showed a good performance in all subjects, higher than 80% of hits. fMRI results showed that the used CPT-IP task activates a network of frontal, parietal and occipital areas, and that these are related to executive and attentional functions. In relation to the use of the CPT to study of attention and working memory, this task provides normative data in healthy adults, and it could be useful to evaluate disorders which have attentional and working memory deficits.

Multiperiod Maximum Loss is time unit invariant.

Science.gov (United States)

Kovacevic, Raimund M; Breuer, Thomas

2016-01-01

Time unit invariance is introduced as an additional requirement for multiperiod risk measures: for a constant portfolio under an i.i.d. risk factor process, the multiperiod risk should equal the one period risk of the aggregated loss, for an appropriate choice of parameters and independent of the portfolio and its distribution. Multiperiod Maximum Loss over a sequence of Kullback-Leibler balls is time unit invariant. This is also the case for the entropic risk measure. On the other hand, multiperiod Value at Risk and multiperiod Expected Shortfall are not time unit invariant.

Dimuon Level-1 invariant mass in 2017 data

CERN Document Server

CMS Collaboration

2018-01-01

This document shows the Level-1 (L1) dimuon invariant mass with and without L1 muon track extrapolation to the collision vertex and how it compares with the offline reconstructed dimuon invariant mass. The plots are made with the data sample collected in 2017. The event selection, the matching algorithm and the results of the L1 dimuon invariant mass are described in the next pages.

Anticedents to entrepreneurial intentions: Testing for measurement invariance for cultural values, attitudes and self-efficacy beliefs across ethnic groups

Directory of Open Access Journals (Sweden)

Boris Urban

2008-10-01

Full Text Available Building on previous research on antecedents of entrepreneurial intentions, various measures were tested across different ethnic groups in South Africa. Factorial homogeneity is an important attribute for any scale intended for use in multicultural research, and since tests of equivalency are not routinely applied, this article hypothesised measurement invariance across ethnic groups. Theoretical discussions on Hofstede’s (2001 value survey module (VSM 94, attitudes towards and beliefs about entrepreneurial intentions, general self-efficacy (GSE, and entrepreneurial self-efficacy (ESE preceded the use of statistical analysis. Confirmatory factor analysis based on 210 respondents indicated that equivalence for the underlying factors across the different ethnic groups could not be established, and that the three groups demonstrated different underlying structures. In conclusion, stereotypic declarations of an integrated South African culture were not supported by this research in terms of entrepreneurial intentions and their antecedents.

The estimation of hemodynamic signals measured by fNIRS response to cold pressor test

Science.gov (United States)

Ansari, M. A.; Fazliazar, E.

2018-04-01

The estimation of cerebral hemodynamic signals has an important role for monitoring the stage of neurological diseases. Functional Near-Infrared Spectroscopy (fNIRS) can be used for monitoring of brain activities. fNIRS utilizes light in the near-infrared spectrum (650-1000 nm) to study the response of the brain vasculature to the changes in neural activities, called neurovascular coupling, within the cortex when cognitive activation occurs. The neurovascular coupling may be disrupted in the brain pathological condition. Therefore, we can also use fNIRS to diagnosis brain pathological conditions or to monitor the efficacy of related treatments. The Cold pressor test (CPT), followed by immersion of dominant hand or foot in the ice water, can induce cortical activities. The perception of pain induced by CPT can be related to cortical neurovascular coupling. Hence, the variation of cortical hemodynamic signals during CPT can be an indicator for studying neurovascular coupling. Here, we study the effect of pain induced by CPT on the temporal variation of concentration of oxyhemoglobin [HbO2] and deoxyhemoglobin [Hb] in the healthy brains. We use fNIRS data collected on forehead during a CPT from 11 healthy subjects, and the average data are compared with post-stimulus pain rating scores. The results show that the variation of [Hb] and [HbO2] are positively correlated with self-reported scores during the CPT. These results depict that fNIRS can be potentially applied to study the decoupling of neurovascular process in brain pathological conditions.

A Balanced Comparison of Object Invariances in Monkey IT Neurons.

Science.gov (United States)

Ratan Murty, N Apurva; Arun, Sripati P

2017-01-01

Our ability to recognize objects across variations in size, position, or rotation is based on invariant object representations in higher visual cortex. However, we know little about how these invariances are related. Are some invariances harder than others? Do some invariances arise faster than others? These comparisons can be made only upon equating image changes across transformations. Here, we targeted invariant neural representations in the monkey inferotemporal (IT) cortex using object images with balanced changes in size, position, and rotation. Across the recorded population, IT neurons generalized across size and position both stronger and faster than to rotations in the image plane as well as in depth. We obtained a similar ordering of invariances in deep neural networks but not in low-level visual representations. Thus, invariant neural representations dynamically evolve in a temporal order reflective of their underlying computational complexity.

Measuring Teacher Job Satisfaction: Assessing Invariance in the Teacher Job Satisfaction Scale (TJSS) Across Six Countries

Science.gov (United States)

Pepe, Alessandro; Addimando, Loredana; Veronese, Guido

2017-01-01

Work and organizational psychology has long been concerned with measuring job satisfaction in organizational contexts, and this has carried across to the field of education, leading to a research focus on the work-related satisfaction of teachers. Today, a myriad of organizations continue to assess employees’ job satisfaction on a routine basis (Liu, Borg, & Spector, 2004). Unfortunately, a sort of balkanization of the field has resulted in the production of dozens of specific measurement tools, making it difficult to cross-compare samples and contexts. The present paper tested the measurement invariance of the Teacher Job Satisfaction Scale (TJSS) in six international cohorts (Netherlands, United States, Russia China, Italy and Palestine) of in-service teachers (N = 2,819). Confirmatory factor analysis and multi-group invariance tests were applied. The TJSS-9 displayed robust psychometric proprieties and no substantial departures from measurement invariance (configural and metric). Future research is required to further test equivalence across additional countries, with view to developing a truly international tool for measuring job satisfaction in teaching. PMID:28904592

Measuring Teacher Job Satisfaction: Assessing Invariance in the Teacher Job Satisfaction Scale (TJSS) Across Six Countries.

Science.gov (United States)

Pepe, Alessandro; Addimando, Loredana; Veronese, Guido

2017-08-01

Work and organizational psychology has long been concerned with measuring job satisfaction in organizational contexts, and this has carried across to the field of education, leading to a research focus on the work-related satisfaction of teachers. Today, a myriad of organizations continue to assess employees' job satisfaction on a routine basis (Liu, Borg, & Spector, 2004). Unfortunately, a sort of balkanization of the field has resulted in the production of dozens of specific measurement tools, making it difficult to cross-compare samples and contexts. The present paper tested the measurement invariance of the Teacher Job Satisfaction Scale (TJSS) in six international cohorts (Netherlands, United States, Russia China, Italy and Palestine) of in-service teachers (N = 2,819). Confirmatory factor analysis and multi-group invariance tests were applied. The TJSS-9 displayed robust psychometric proprieties and no substantial departures from measurement invariance (configural and metric). Future research is required to further test equivalence across additional countries, with view to developing a truly international tool for measuring job satisfaction in teaching.

Measuring Teacher Job Satisfaction: Assessing Invariance in the Teacher Job Satisfaction Scale (TJSS Across Six Countries

Directory of Open Access Journals (Sweden)

Alessandro Pepe

2017-08-01

Full Text Available Work and organizational psychology has long been concerned with measuring job satisfaction in organizational contexts, and this has carried across to the field of education, leading to a research focus on the work-related satisfaction of teachers. Today, a myriad of organizations continue to assess employees’ job satisfaction on a routine basis (Liu, Borg, & Spector, 2004. Unfortunately, a sort of balkanization of the field has resulted in the production of dozens of specific measurement tools, making it difficult to cross-compare samples and contexts. The present paper tested the measurement invariance of the Teacher Job Satisfaction Scale (TJSS in six international cohorts (Netherlands, United States, Russia China, Italy and Palestine of in-service teachers (N = 2,819. Confirmatory factor analysis and multi-group invariance tests were applied. The TJSS-9 displayed robust psychometric proprieties and no substantial departures from measurement invariance (configural and metric. Future research is required to further test equivalence across additional countries, with view to developing a truly international tool for measuring job satisfaction in teaching.

Invariant probabilities of transition functions

CERN Document Server

Zaharopol, Radu

2014-01-01

The structure of the set of all the invariant probabilities and the structure of various types of individual invariant probabilities of a transition function are two topics of significant interest in the theory of transition functions, and are studied in this book. The results obtained are useful in ergodic theory and the theory of dynamical systems, which, in turn, can be applied in various other areas (like number theory). They are illustrated using transition functions defined by flows, semiflows, and one-parameter convolution semigroups of probability measures. In this book, all results on transition probabilities that have been published by the author between 2004 and 2008 are extended to transition functions. The proofs of the results obtained are new. For transition functions that satisfy very general conditions the book describes an ergodic decomposition that provides relevant information on the structure of the corresponding set of invariant probabilities. Ergodic decomposition means a splitting of t...

Riemann quasi-invariants

International Nuclear Information System (INIS)

Pokhozhaev, Stanislav I

2011-01-01

The notion of Riemann quasi-invariants is introduced and their applications to several conservation laws are considered. The case of nonisentropic flow of an ideal polytropic gas is analysed in detail. Sufficient conditions for gradient catastrophes are obtained. Bibliography: 16 titles.

Modular categories and 3-manifold invariants

International Nuclear Information System (INIS)

Tureav, V.G.

1992-01-01

The aim of this paper is to give a concise introduction to the theory of knot invariants and 3-manifold invariants which generalize the Jones polynomial and which may be considered as a mathematical version of the Witten invariants. Such a theory was introduced by N. Reshetikhin and the author on the ground of the theory of quantum groups. here we use more general algebraic objects, specifically, ribbon and modular categories. Such categories in particular arise as the categories of representations of quantum groups. The notion of modular category, interesting in itself, is closely related to the notion of modular tensor category in the sense of G. Moore and N. Seiberg. For simplicity we restrict ourselves in this paper to the case of closed 3-manifolds

Knot invariants and higher representation theory

CERN Document Server

Webster, Ben

2018-01-01

The author constructs knot invariants categorifying the quantum knot variants for all representations of quantum groups. He shows that these invariants coincide with previous invariants defined by Khovanov for \\mathfrak{sl}_2 and \\mathfrak{sl}_3 and by Mazorchuk-Stroppel and Sussan for \\mathfrak{sl}_n. The author's technique is to study 2-representations of 2-quantum groups (in the sense of Rouquier and Khovanov-Lauda) categorifying tensor products of irreducible representations. These are the representation categories of certain finite dimensional algebras with an explicit diagrammatic presentation, generalizing the cyclotomic quotient of the KLR algebra. When the Lie algebra under consideration is \\mathfrak{sl}_n, the author shows that these categories agree with certain subcategories of parabolic category \\mathcal{O} for \\mathfrak{gl}_k.

Separate T, CP, CPT Asymmetries in Neutral Meson Transitions

Science.gov (United States)

Bernabéu, José

2017-07-01

Symmetries, and Symmetry Breakings, in the Laws of Physics play a crucial role in Fundamental Science. Parity and Charge Conjugation Violations prompted the consideration of Chiral Fields in the construction of the Standard Model, whereas CP-Violation needed at least three families of Quarks leading to Flavour Physics. In this Lecture I will discuss the Conceptual Basis and the present experimental results for a Direct Evidence of Separate Reversal-in-Time T, CP and CPT Genuine Asymmetries in Decaying Particles like Neutral Meson Transitions, using Quantum Entanglement and the Decay as a Filtering Measurement. The eight transitions associated to the Flavour-CP eigenstate decay products of entangled neutral mesons have demonstrated with impressive significance a separate evidence of TRV and CPV in Bd-physics, whereas a CPTV asymmetry shows a 2-σ effect interpreted as an upper limit. Novel CPTV observables are discussed for K and Bd transitions. Their observation would lead to a change of paradigm beyond Quantum Field Theory, however there is nothing in Quantum Mechanics forbidding CPTV. A clean methodology to disentangle CPTV effects in the Hamiltonian dynamics and the ω-effect weakening Entanglement in a given experiment is discussed.

Existence of a last invariant of conservative motion

International Nuclear Information System (INIS)

Hall, L.S.

1982-01-01

A general theory of integrable systems in two dimensions is formulated and applied. (The theory also has applications to more dimensions). The constraints are found which admit to general integrability of the orbits for magnetic forces as well as for forces derivable from a potential. When a system admits a given invariant, the invariant is found. A number of examples including known and apparently previously unknown invariants are given. The theory of exact integrals of the motion also can be extended to the derivation of approximate invariants. The general theory admits a variational principle, among other approximation techniques, for the computation of a best approximate invariant. The problem of the general cubic potential with one symmetric coordinate, V = 1/2 Ax 2 + 1/2 By 2 + Cx 2 y + 1/3 Dy 3 (of which the well-studied Henon-Heiles potential is the special case for A = B and C = -D), is examined in detail

Knot invariants derived from quandles and racks

OpenAIRE

Kamada, Seiichi

2002-01-01

The homology and cohomology of quandles and racks are used in knot theory: given a finite quandle and a cocycle, we can construct a knot invariant. This is a quick introductory survey to the invariants of knots derived from quandles and racks.

Design of a spin-flip cavity for the measurement of the antihydrogen hyperfine structure

CERN Document Server

Kroyer, T

2008-01-01

In the framework of the ASACUSA collaboration at the CERN Antiproton Decelerator an experiment for precisely testing the CPT invariance of the hydrogen hyperfine structure is currently being designed. An integral part of the set-up is the 1.42 GHz spin-flipping cavity, which should have a good field homogeneity over the large aperture of the antihydrogen beam. After the evaluation of various approaches a structure based on a resonant stripline is proposed as a concrete cavity design. For this structure the field homogeneity, undesired modes, coupling and power issues are discussed in detail.

The ASACUSA Micromegas Tracker: A cylindrical, bulk Micromegas detector for antimatter research

Energy Technology Data Exchange (ETDEWEB)

Radics, B., E-mail: balint.radics@riken.jp; Nagata, Y.; Yamazaki, Y. [Atomic Physics Laboratory, RIKEN, Saitama 351-0198 (Japan); Ishikawa, S.; Kuroda, N.; Matsuda, Y. [Institute of Physics, Graduate School of Arts and Sciences, University of Tokyo, Tokyo 153-8902 (Japan); Anfreville, M.; Aune, S.; Boyer, M.; Chateau, F.; Combet, M.; Granelli, R.; Legou, P.; Mandjavidze, I.; Procureur, S.; Riallot, M.; Vallage, B.; Vandenbroucke, M. [Irfu, CEA, Centre de Saclay, 91191 Gif sur Yvette (France)

2015-08-15

The ASACUSA Micromegas Tracker (AMT; ASACUSA: Atomic Spectroscopy and Collisions Using Slow Antiprotons) was designed to be able to reconstruct antiproton-nucleon annihilation vertices in three dimensions. The goal of this device is to study antihydrogen formation processes in the ASACUSA cusp trap, which was designed to synthesise a spin-polarised antihydrogen beam for precise tests of Charge, Parity, and Time (CPT) symmetry invariance. This paper discusses the structure and technical details of an AMT detector built into such an environment, its data acquisition system and the first performance with cosmic rays.

The ASACUSA Micromegas Tracker: A cylindrical, bulk Micromegas detector for antimatter research.

Science.gov (United States)

Radics, B; Nagata, Y; Yamazaki, Y; Ishikawa, S; Kuroda, N; Matsuda, Y; Anfreville, M; Aune, S; Boyer, M; Chateau, F; Combet, M; Granelli, R; Legou, P; Mandjavidze, I; Procureur, S; Riallot, M; Vallage, B; Vandenbroucke, M

2015-08-01

The ASACUSA Micromegas Tracker (AMT; ASACUSA: Atomic Spectroscopy and Collisions Using Slow Antiprotons) was designed to be able to reconstruct antiproton-nucleon annihilation vertices in three dimensions. The goal of this device is to study antihydrogen formation processes in the ASACUSA cusp trap, which was designed to synthesise a spin-polarised antihydrogen beam for precise tests of Charge, Parity, and Time (CPT) symmetry invariance. This paper discusses the structure and technical details of an AMT detector built into such an environment, its data acquisition system and the first performance with cosmic rays.

Time reversal invariance - a test in free neutron decay

Energy Technology Data Exchange (ETDEWEB)

Lising, Laura Jean [Univ. of California, Berkeley, CA (United States)

1999-01-01

Time reversal invariance violation plays only a small role in the Standard Model, and the existence of a T-violating effect above the predicted level would be an indication of new physics. A sensitive probe of this symmetry in the weak interaction is the measurement of the T-violating ''D''-correlation in the decay of free neutrons. The triple-correlation Dσ_n∙p_e x p_v involves three kinematic variables, the neutron spin, electron momentu, and neutrino (or proton) momentum, and changes sign under time reversal. This experiment detects the decay products of a polarized cold neutron beam with an octagonal array of scintillation and solid-state detectors. Data from first run at NIST's Cold Neutron Research Facility give a D-coefficient of -0.1 ± 1.3(stat.) ± 0.7(syst) x 10^-3 This measurement has the greatest bearing on extensions to the Standard model that incorporate leptoquarks, although exotic fermion and lift-right symmetric models also allow a D as large as the present limit.

Invariant approach to CP in unbroken Δ(27

Directory of Open Access Journals (Sweden)

Gustavo C. Branco

2015-10-01

Full Text Available The invariant approach is a powerful method for studying CP violation for specific Lagrangians. The method is particularly useful for dealing with discrete family symmetries. We focus on the CP properties of unbroken Δ(27 invariant Lagrangians with Yukawa-like terms, which proves to be a rich framework, with distinct aspects of CP, making it an ideal group to investigate with the invariant approach. We classify Lagrangians depending on the number of fields transforming as irreducible triplet representations of Δ(27. For each case, we construct CP-odd weak basis invariants and use them to discuss the respective CP properties. We find that CP violation is sensitive to the number and type of Δ(27 representations.

Inertial Spontaneous Symmetry Breaking and Quantum Scale Invariance

Energy Technology Data Exchange (ETDEWEB)

Ferreira, Pedro G. [Oxford U.; Hill, Christopher T. [Fermilab; Ross, Graham G. [Oxford U., Theor. Phys.

2018-01-23

Weyl invariant theories of scalars and gravity can generate all mass scales spontaneously, initiated by a dynamical process of "inertial spontaneous symmetry breaking" that does not involve a potential. This is dictated by the structure of the Weyl current, $K_\\mu$, and a cosmological phase during which the universe expands and the Einstein-Hilbert effective action is formed. Maintaining exact Weyl invariance in the renormalised quantum theory is straightforward when renormalisation conditions are referred back to the VEV's of fields in the action of the theory, which implies a conserved Weyl current. We do not require scale invariant regulators. We illustrate the computation of a Weyl invariant Coleman-Weinberg potential.

Measurement invariance of the strength of motivation for medical school: a multi-group confirmatory factor analysis.

Science.gov (United States)

An, M; Kusurkar, R A; Li, L; Xiao, Y; Zheng, C; Hu, J; Chen, M

2017-07-11

The Strength of Motivation for Medical School-Revised (SMMS-R) questionnaire measures students' motivation for studying medicine. It includes three subscales: 'willingness to sacrifice', 'readiness to start', and 'persistence'. Measurement invariance is a prerequisite for group comparisons. The objectives of this study were to verify the factorial structure of the SMMS-R questionnaire and to investigate it's measurement invariance. A total of 989 medical students were approached, 930 cases were kept for data analysis. Factorial structure of and measurement invariance of the SMMS-R were tested using single and multiple group confirmatory factor analyses with Mplus. Trational Cronbach's α along with McDonald's ω and glb were used to measure internal consistency for each subscale. Internal consistency for subscales and the full instrument were within the acceptable range. A 3-factor structure of the Chinese version of the SMMS-R was supported. Full configural, metric and partial scalar invariance were obtained. The SMMS-R showed measurement invariance across gender and two independent samples. So it can be used for group and cross-cultural comparisons.

The Shame and Guilt Scales of the Test of Self-Conscious Affect-Adolescent (TOSCA-A): Factor Structure, Concurrent and Discriminant Validity, and Measurement and Structural Invariance Across Ratings of Males and Females.

Science.gov (United States)

Watson, Shaun; Gomez, Rapson; Gullone, Eleonora

2017-06-01

This study examined various psychometric properties of the items comprising the shame and guilt scales of the Test of Self-Conscious Affect-Adolescent. A total of 563 adolescents (321 females and 242 males) completed these scales, and also measures of depression and empathy. Confirmatory factor analysis provided support for an oblique two-factor model, with the originally proposed shame and guilt items comprising shame and guilt factors, respectively. Also, shame correlated with depression positively and had no relation with empathy. Guilt correlated with depression negatively and with empathy positively. Thus, there was support for the convergent and discriminant validity of the shame and guilt factors. Multiple-group confirmatory factor analysis comparing females and males, based on the chi-square difference test, supported full metric invariance, the intercept invariance of 26 of the 30 shame and guilt items, and higher latent mean scores among females for both shame and guilt. Comparisons based on the difference in root mean squared error of approximation values supported full measurement invariance and no gender difference for latent mean scores. The psychometric and practical implications of the findings are discussed.

Invariance as a Tool for Ontology of Information

Directory of Open Access Journals (Sweden)

Marcin J. Schroeder

2016-03-01

Full Text Available Attempts to answer questions regarding the ontological status of information are frequently based on the assumption that information should be placed within an already existing framework of concepts of established ontological statuses related to science, in particular to physics. However, many concepts of physics have undetermined or questionable ontological foundations. We can look for a solution in the recognition of the fundamental role of invariance with respect to a change of reference frame and to other transformations as a criterion for objective existence. The importance of invariance (symmetry as a criterion for a primary ontological status can be identified in the methodology of physics from its beginnings in the work of Galileo, to modern classifications of elementary particles. Thus, the study of the invariance of the theoretical description of information is proposed as the first step towards ontology of information. With the exception of only a few works among publications which set the paradigm of information studies, the issues of invariance were neglected. Orthodox analysis of information lacks conceptual framework for the study of invariance. The present paper shows how invariance can be formalized for the definition of information and, accompanying it, mathematical formalism proposed by the author in his earlier publications.

Slow feature analysis: unsupervised learning of invariances.

Science.gov (United States)

Wiskott, Laurenz; Sejnowski, Terrence J

2002-04-01

Invariant features of temporally varying signals are useful for analysis and classification. Slow feature analysis (SFA) is a new method for learning invariant or slowly varying features from a vectorial input signal. It is based on a nonlinear expansion of the input signal and application of principal component analysis to this expanded signal and its time derivative. It is guaranteed to find the optimal solution within a family of functions directly and can learn to extract a large number of decorrelated features, which are ordered by their degree of invariance. SFA can be applied hierarchically to process high-dimensional input signals and extract complex features. SFA is applied first to complex cell tuning properties based on simple cell output, including disparity and motion. Then more complicated input-output functions are learned by repeated application of SFA. Finally, a hierarchical network of SFA modules is presented as a simple model of the visual system. The same unstructured network can learn translation, size, rotation, contrast, or, to a lesser degree, illumination invariance for one-dimensional objects, depending on only the training stimulus. Surprisingly, only a few training objects suffice to achieve good generalization to new objects. The generated representation is suitable for object recognition. Performance degrades if the network is trained to learn multiple invariances simultaneously.

Normal Anti-Invariant Submanifolds of Paraquaternionic Kähler Manifolds

Directory of Open Access Journals (Sweden)

Novac-Claudiu Chiriac

2006-12-01

Full Text Available We introduce normal anti-invariant submanifolds of paraquaternionic Kähler manifolds and study the geometric structures induced on them. We obtain necessary and sufficient conditions for the integrability of the distributions defined on a normal anti-invariant submanifold. Also, we present characterizations of local (global anti-invariant products.

Perturbation to Unified Symmetry and Adiabatic Invariants for Relativistic Hamilton Systems

International Nuclear Information System (INIS)

Zhang Mingjiang; Fang Jianhui; Lu Kai; Pang Ting; Lin Peng

2009-01-01

Based on the concept of adiabatic invariant, the perturbation to unified symmetry and adiabatic invariants for relativistic Hamilton systems are studied. The definition of the perturbation to unified symmetry for the system is presented, and the criterion of the perturbation to unified symmetry is given. Meanwhile, the Noether adiabatic invariants, the generalized Hojman adiabatic invariants, and the Mei adiabatic invariants for the perturbed system are obtained. (general)

Testing Lorentz invariance emergence in Ising Model using lattice Monte Carlo simulations

CERN Document Server

Stojku, Stefan

2017-01-01

All measurements performed so far at the observable energy scales show no violation of Lorentz invariance. However, it is yet impossible to check experimentally whether this symmetry holds at high energies such as the Planck scale. Recently, theories of gravitation with Lorentz violation, known as Horava-Lifshitz gravity [1, 2] have gained significant attention by treating Lorentz symmetry as an emergent phenomenon. A Lif-shitz type theory assumes an anisotropic scaling between space and time weighted by some critical exponent. In order for these theories to be viable candidates for quantum gravity description of the nature, Lorentz symmetry needs to be recovered at low energies.

Analysing, Interpreting, and Testing the Invariance of the Actor-Partner Interdependence Model

Directory of Open Access Journals (Sweden)

Gareau, Alexandre

2016-09-01

Full Text Available Although in recent years researchers have begun to utilize dyadic data analyses such as the actor-partner interdependence model (APIM, certain limitations to the applicability of these models still exist. Given the complexity of APIMs, most researchers will often use observed scores to estimate the model's parameters, which can significantly limit and underestimate statistical results. The aim of this article is to highlight the importance of conducting a confirmatory factor analysis (CFA of equivalent constructs between dyad members (i.e. measurement equivalence/invariance; ME/I. Different steps for merging CFA and APIM procedures will be detailed in order to shed light on new and integrative methods.

Multi-Population Invariance with Dichotomous Measures: Combining Multi-Group and MIMIC Methodologies in Evaluating the General Aptitude Test in the Arabic Language

Science.gov (United States)

Sideridis, Georgios D.; Tsaousis, Ioannis; Al-harbi, Khaleel A.

2015-01-01

The purpose of the present study was to extend the model of measurement invariance by simultaneously estimating invariance across multiple populations in the dichotomous instrument case using multi-group confirmatory factor analytic and multiple indicator multiple causes (MIMIC) methodologies. Using the Arabic version of the General Aptitude Test…

Testing the Factorial Invariance of the English and Filipino Versions of the Inventory of School Motivation with Bilingual Students in the Philippines

Science.gov (United States)

Ganotice, Fraide A., Jr.; Bernardo, Allan B. I.; King, Ronnel B.

2012-01-01

The study explored the invariance of Filipino and English versions of the Inventory of School Motivation (ISM) for Filipino-English bilingual students. There was invariance in the factor structure and factor loadings across the two language versions. Between-network construct validation showed consistent associations between ISM-mastery goals and…

Tests of fundamental symmetries with trapped antihydrogen

DEFF Research Database (Denmark)

Rasmussen, Chris Ørum

2016-01-01

Antihydrogen is the simplest pure antimatter atomic system, and it allows for direct tests of CPT symmetry as well as the weak equivalence principle. Furthermore the study of antihydrogen may provide clues to the matter- antimatter asymmetry observed in the universe - one of the major unanswered...

Dark coupling and gauge invariance

International Nuclear Information System (INIS)

Gavela, M.B.; Honorez, L. Lopez; Mena, O.; Rigolin, S.

2010-01-01

We study a coupled dark energy-dark matter model in which the energy-momentum exchange is proportional to the Hubble expansion rate. The inclusion of its perturbation is required by gauge invariance. We derive the linear perturbation equations for the gauge invariant energy density contrast and velocity of the coupled fluids, and we determine the initial conditions. The latter turn out to be adiabatic for dark energy, when assuming adiabatic initial conditions for all the standard fluids. We perform a full Monte Carlo Markov Chain likelihood analysis of the model, using WMAP 7-year data

Dark Coupling and Gauge Invariance

CERN Document Server

Gavela, M B; Mena, O; Rigolin, S

2010-01-01

We study a coupled dark energy-dark matter model in which the energy-momentum exchange is proportional to the Hubble expansion rate. The inclusion of its perturbation is required by gauge invariance. We derive the linear perturbation equations for the gauge invariant energy density contrast and velocity of the coupled fluids, and we determine the initial conditions. The latter turn out to be adiabatic for dark energy, when assuming adiabatic initial conditions for all the standard fluids. We perform a full Monte Carlo Markov Chain likelihood analysis of the model, using WMAP 7-year data.

Spin foam diagrammatics and topological invariance

International Nuclear Information System (INIS)

Girelli, Florian; Oeckl, Robert; Perez, Alejandro

2002-01-01

We provide a simple proof of the topological invariance of the Turaev-Viro model (corresponding to simplicial 3D pure Euclidean gravity with cosmological constant) by means of a novel diagrammatic formulation of the state sum models for quantum BF theories. Moreover, we prove the invariance under more general conditions allowing the state sum to be defined on arbitrary cellular decompositions of the underlying manifold. Invariance is governed by a set of identities corresponding to local gluing and rearrangement of cells in the complex. Due to the fully algebraic nature of these identities our results extend to a vast class of quantum groups. The techniques introduced here could be relevant for investigating the scaling properties of non-topological state sums, proposed as models of quantum gravity in 4D, under refinement of the cellular decomposition

Second-order gauge-invariant perturbations during inflation

International Nuclear Information System (INIS)

Finelli, F.; Marozzi, G.; Vacca, G. P.; Venturi, G.

2006-01-01

The evolution of gauge invariant second-order scalar perturbations in a general single field inflationary scenario are presented. Different second-order gauge-invariant expressions for the curvature are considered. We evaluate perturbatively one of these second order curvature fluctuations and a second-order gauge-invariant scalar field fluctuation during the slow-roll stage of a massive chaotic inflationary scenario, taking into account the deviation from a pure de Sitter evolution and considering only the contribution of super-Hubble perturbations in mode-mode coupling. The spectra resulting from their contribution to the second order quantum correlation function are nearly scale-invariant, with additional logarithmic corrections with respect to the first order spectrum. For all scales of interest the amplitude of these spectra depends on the total number of e-folds. We find, on comparing first and second order perturbation results, an upper limit to the total number of e-folds beyond which the two orders are comparable

Field transformations, collective coordinates and BRST invariance

International Nuclear Information System (INIS)

Alfaro, J.; Damgaard, P.H.

1989-12-01

A very large class of general field transformations can be viewed as a field theory generalization of the method of collective coordinates. The introduction of new variables induces a gauge invariance in the transformed theory, and the freedom left in gauge fixing this new invariance can be used to find equivalent formulations of the same theory. First the Batalin-Fradkin-Vilkovisky formalism is applied to the Hamiltonian formulation of physical systems that can be described in terms of collective coordinates. We then show how this type of collective coordinate scheme can be generalized to field transformations, and discuss the War Identities of the associated BRST invariance. For Yang-Mills theory a connection to topological field theory and the background field method is explained in detail. In general the resulting BRST invariance we find hidden in any quantum field theory can be viewed as a consequence of our freedom in choosing a basis of coordinates φ(χ) in the action S[φ]. (orig.)

Modified dispersion relations, inflation, and scale invariance

Science.gov (United States)

Bianco, Stefano; Friedhoff, Victor Nicolai; Wilson-Ewing, Edward

2018-02-01

For a certain type of modified dispersion relations, the vacuum quantum state for very short wavelength cosmological perturbations is scale-invariant and it has been suggested that this may be the source of the scale-invariance observed in the temperature anisotropies in the cosmic microwave background. We point out that for this scenario to be possible, it is necessary to redshift these short wavelength modes to cosmological scales in such a way that the scale-invariance is not lost. This requires nontrivial background dynamics before the onset of standard radiation-dominated cosmology; we demonstrate that one possible solution is inflation with a sufficiently large Hubble rate, for this slow roll is not necessary. In addition, we also show that if the slow-roll condition is added to inflation with a large Hubble rate, then for any power law modified dispersion relation quantum vacuum fluctuations become nearly scale-invariant when they exit the Hubble radius.

Fully Numerical Methods for Continuing Families of Quasi-Periodic Invariant Tori in Astrodynamics

Science.gov (United States)

Baresi, Nicola; Olikara, Zubin P.; Scheeres, Daniel J.

2018-01-01

Quasi-periodic invariant tori are of great interest in astrodynamics because of their capability to further expand the design space of satellite missions. However, there is no general consent on what is the best methodology for computing these dynamical structures. This paper compares the performance of four different approaches available in the literature. The first two methods compute invariant tori of flows by solving a system of partial differential equations via either central differences or Fourier techniques. In contrast, the other two strategies calculate invariant curves of maps via shooting algorithms: one using surfaces of section, and one using a stroboscopic map. All of the numerical procedures are tested in the co-rotating frame of the Earth as well as in the planar circular restricted three-body problem. The results of our numerical simulations show which of the reviewed procedures should be preferred for future studies of astrodynamics systems.

Real-time trajectory analysis using stacked invariance methods

OpenAIRE

Kitts, B.

1998-01-01

Invariance methods are used widely in pattern recognition as a preprocessing stage before algorithms such as neural networks are applied to the problem. A pattern recognition system has to be able to recognise objects invariant to scale, translation, and rotation. Presumably the human eye implements some of these preprocessing transforms in making sense of incoming stimuli, for example, placing signals onto a log scale. This paper surveys many of the commonly used invariance methods, and asse...

Invariant subsets under compact quantum group actions

OpenAIRE

Huang, Huichi

2012-01-01

We investigate compact quantum group actions on unital $C^*$-algebras by analyzing invariant subsets and invariant states. In particular, we come up with the concept of compact quantum group orbits and use it to show that countable compact metrizable spaces with infinitely many points are not quantum homogeneous spaces.

Borromean surgery formula for the Casson invariant

DEFF Research Database (Denmark)

Meilhan, Jean-Baptiste Odet Thierry

2008-01-01

It is known that every oriented integral homology 3-sphere can be obtained from S3 by a finite sequence of Borromean surgeries. We give an explicit formula for the variation of the Casson invariant under such a surgery move. The formula involves simple classical invariants, namely the framing...

Translationally invariant and non-translationally invariant empirical effective interactions

International Nuclear Information System (INIS)

Golin, M.; Zamick, L.

1975-01-01

In this work empirical deficiencies of the core-renormalized realistic effective interactions are examined and simple corrective potentials are sought. The inability of the current realistic interactions to account for the energies of isobaric analog states is noted, likewise they are unable to reproduce the changes in the single-particle energies, as one goes from one closed shell to another. It is noted that the Schiffer interaction gives better results for these gross properties and this is attributed to a combination of several facts. First, to the inclusion of long range terms in the Schiffer potential, then to the presence of relative p-state terms (l=1), in addition to the usual relative s-state terms (l=0). The strange shape of the above interaction is further attributed to the fact that it is translationally invariant whereas the theory of core-polarization yields non-translationally invariant potentials. Consequently, as a correction to the monopole deficiencies of the realistic interactions the term Vsub(mon)=ar 2 (1)r 2 (2)+r 2 (1)+β[r 4 (1)r 2 (2)r 4 (2) ] is proposed. (Auth.)

Conformal (WEYL) invariance and Higgs mechanism

International Nuclear Information System (INIS)

Zhao Shucheng.

1991-10-01

A massive Yang-Mills field theory with conformal invariance and gauge invariance is proposed. It involves gravitational and various gauge interactions, in which all the mass terms appear as a uniform form of interaction m(x) KΦ(x). When the conformal symmetry is broken spontaneously and gravitation is ignored, the Higgs field emerges naturally, where the imaginary mass μ can be described as a background curvature. (author). 7 refs

Measurement of job motivation in TEDS-M: testing for invariance across countries and cultures

OpenAIRE

Laschke, Christin; Blömeke, Sigrid

2016-01-01

Abstract The paper presents the challenges of cross-country and cross-cultural research on the motivation to become a mathematics teacher based on data from the “Teacher Education and Development Study in Mathematics (TEDS-M)”. Referring to studies from cross-cultural psychology, measurement invariance (MI) of constructs representing different motivations to become a teacher was examined in confirmatory factor analysis (CFA) across the countries that participated in TEDS-M. The data supported...

CPT-11/bevacizumab for the treatment of refractory brain metastases in patients with HER2-neu-positive breast cancer.

Science.gov (United States)

Sengupta, S; Rojas, R; Mahadevan, A; Kasper, E; Jeyapalan, S

2015-04-01

Nervous system relapse of patients with advanced HER2-neu-positive breast cancer is an increasing problem, with one-third of women developing brain metastases. Standard therapies using steroids, surgery and radiotherapy do not provide a lasting response. We evaluated CPT-11 and bevacizumab, which can both cross the blood-brain barrier, as combination therapy to treat HER2-neu-positive breast cancer with brain metastases.

Topological excitations in U(1) -invariant theories

International Nuclear Information System (INIS)

Savit, R.

1977-01-01

A class of U(1) -invariant theories in d dimensions is introduced on a lattice. These theories are labeled by a simplex number s, with 1 < or = s < d. The case with s = 1 is the X-Y model; and s = 2 gives compact photodynamics. An exact duality transformation is applied to show that the U(1) -invariant theory in d dimensions with simplex number s is the same as a similar theory in d dimensions but which is Z /sub infinity/-invariant and has simplex number s = d-s. This dual theory describes the topological excitations of the original theory. These excitations are of dimension s - 1

Integrated Advanced Microwave Sounding Unit-A (AMSU-A). Engineering Test Report: AMSU-A1 EOS Instrument, (S/N 202) Qualification Level Vibration Tests of August/September 1998, (S/O 565632, OC-417) Plus Addendum A

Science.gov (United States)

Heffer, R.

1998-01-01

The purpose of this report is to present a qualification level vibration testing performed on the S/N 202, EOS AMSU-A1 Instrument was vibration tested to qualification levels per the Ref. 1 shop order. The instrument withstood the 8 g sine sweep test, the 7.5 Grms random vibration test, and the 18.75 g sine burst test in each of the three orthogonal axes. Some loss of transmissibility, however, is seen in the lower reflector after Z-axis random vibration. The test sequence was not without incidence. Failure of Channel 7 in the Limited Performance Test (LPT) performed after completion of the 1 st (X-axis) axis vibration sequence, required replacement of the DRO and subsequent re-testing of the instrument. The post-vibration comprehensive performance test (CPT) was successfully run after completion of the three axes of vibration with the replacement component installed in the instrument. Passing the CPT signified the successful completion of the S/N 202 A1 qualification vibration testing.

Invariance group of the Finster metric function

International Nuclear Information System (INIS)

Asanov, G.S.

1985-01-01

An invariance group of the Finsler metric function is introduced and studied that directly generalized the respective concept (a group of Euclidean rolations) of the Rieman geometry. A sequential description of the isotopic invariance of physical fields on the base of the Finsler geometry is possible in terms of this group

Note on Weyl versus conformal invariance in field theory

Energy Technology Data Exchange (ETDEWEB)

Wu, Feng [Nanchang University, Department of Physics, Nanchang (China)

2017-12-15

It was argued recently that conformal invariance in flat spacetime implies Weyl invariance in a general curved background for unitary theories and possible anomalies in the Weyl variation of scalar operators are identified. We argue that generically unitarity alone is not sufficient for a conformal field theory to be Weyl invariant. Furthermore, we show explicitly that when a unitary conformal field theory couples to gravity in a Weyl-invariant way, each primary scalar operator that is either relevant or marginal in the unitary conformal field theory corresponds to a Weyl-covariant operator in the curved background. (orig.)

Teste cardiopulmonar do exercício na prática clínica Cardiopulmonary stress testing in clinical practice

Directory of Open Access Journals (Sweden)

Eva Cantalejo Munhoz Stadler de Souza

2000-12-01

Full Text Available O teste cardiopulmonar do exercício (CPX apresenta-se como uma metodologia de grande utilidade diagnóstica e prognóstica. O presente estudo teve por objetivo demonstrar que os dados obtidos em laboratório fora do ambiente hospitalar comportam-se como os dados descritos na literatura, com aplicabilidade na prática clínica em nosso meio. METODOLOGIA: Trata-se de um relato de experiência, através da análise retrospectiva dos casos. O CPX foi realizado em condições de laboratório controladas, com bocal e clipe nasal, protocolo de rampa em esteira rolante e eletrocardiograma de 13 canais. RESULTADOS: Entre os 261 testes, 53,3% eram em homens, idade média de 48,2 ± 14,3 anos; ativos (45,2% ou sedentários (34,5%. A capacidade aeróbia máxima foi superior e com declínio significativo para cada década de aumento na faixa etária entre os homens, enquanto nas mulheres o declínio significativo ocorreu entre os 30 e 60 anos. As mulheres apresentaram maior distribuição (p = 0,0006 nas classes funcionais "em programa de treinamento ou bem treinadas e motivadas". O consumo de oxigênio pico (O2 foi significativamente superior nos testes máximos, mas o O2 do limiar anaeróbio (O2LA não apresentou diferenças significativas, quando o teste obtido foi máximo ou submáximo. A capacidade funcional, avaliada pelo O2LA como porcentagem do O2 máximo previsto, comparado à porcentagem do O2 máximo atingido, classificou mais indivíduos com compromisso circulatório (p = 0,002 ou com menor aptidão física em comparação com pacientes ativos ou em programa de treinamento (p O2 máximo previsto foi a causa mais comum de anormalidade, mais freqüente e significativo entre as mulheres. CONCLUSÃO: Os dados obtidos são comparáveis aos descritos na literatura, sugerindo que o CPX é uma metodologia factível, que poderia ser empregada rotineiramente na prática clínica em nosso meio.Cardiopulmonary stress testing (CPT is a very useful tool to

Anti-hydrogen: The cusp between quantum mechanics and general relativity

International Nuclear Information System (INIS)

Noyes, H.P.

1992-09-01

We argue that the crossing (CPT) symmetry of relativistic quantum mechanics requires that both the coulombic and the Newtonian force between pairs of particles will reverse when one is replaced by its anti-particle. For consistency, this requires a theory in which both the equivalence principles and gauge invariance are abandoned. thus whether anti-hydrogen ''falls'' up or down will provide an experiment crusis separating general relativity and gauge invariance from this version of quantum mechanics

Exploring the Measurement Properties of the eHealth Literacy Scale (eHEALS) Among Baby Boomers: A Multinational Test of Measurement Invariance.

Science.gov (United States)

Sudbury-Riley, Lynn; FitzPatrick, Mary; Schulz, Peter J

2017-02-27

The eHealth Literacy Scale (eHEALS) is one of only a few available measurement scales to assess eHealth literacy. Perhaps due to the relative paucity of such measures and the rising importance of eHealth literacy, the eHEALS is increasingly a choice for inclusion in a range of studies across different groups, cultures, and nations. However, despite its growing popularity, questions have been raised over its theoretical foundations, and the factorial validity and multigroup measurement properties of the scale are yet to be investigated fully. The objective of our study was to examine the factorial validity and measurement invariance of the eHEALS among baby boomers (born between 1946 and 1964) in the United States, United Kingdom, and New Zealand who had used the Internet to search for health information in the last 6 months. Online questionnaires collected data from a random sample of baby boomers from the 3 countries of interest. The theoretical underpinning to eHEALS comprises social cognitive theory and self-efficacy theory. Close scrutiny of eHEALS with analysis of these theories suggests a 3-factor structure to be worth investigating, which has never before been explored. Structural equation modeling tested a 3-factor structure based on the theoretical underpinning to eHEALS and investigated multinational measurement invariance of the eHEALS. We collected responses (N=996) to the questionnaires using random samples from the 3 countries. Results suggest that the eHEALS comprises a 3-factor structure with a measurement model that falls within all relevant fit indices (root mean square error of approximation, RMSEA=.041, comparative fit index, CFI=.986). Additionally, the scale demonstrates metric invariance (RMSEA=.040, CFI=.984, ΔCFI=.002) and even scalar invariance (RMSEA=.042, CFI=.978, ΔCFI=.008). To our knowledge, this is the first study to demonstrate multigroup factorial equivalence of the eHEALS, and did so based on data from 3 diverse nations and

Invariant functionals in higher-spin theory

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M.A. Vasiliev

2017-03-01

Full Text Available A new construction for gauge invariant functionals in the nonlinear higher-spin theory is proposed. Being supported by differential forms closed by virtue of the higher-spin equations, invariant functionals are associated with central elements of the higher-spin algebra. In the on-shell AdS4 higher-spin theory we identify a four-form conjectured to represent the generating functional for 3d boundary correlators and a two-form argued to support charges for black hole solutions. Two actions for 3d boundary conformal higher-spin theory are associated with the two parity-invariant higher-spin models in AdS4. The peculiarity of the spinorial formulation of the on-shell AdS3 higher-spin theory, where the invariant functional is supported by a two-form, is conjectured to be related to the holomorphic factorization at the boundary. The nonlinear part of the star-product function F⁎(B(x in the higher-spin equations is argued to lead to divergencies in the boundary limit representing singularities at coinciding boundary space–time points of the factors of B(x, which can be regularized by the point splitting. An interpretation of the RG flow in terms of proposed construction is briefly discussed.

Quantum implications of a scale invariant regularization

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Ghilencea, D. M.

2018-04-01