WorldWideScience

Sample records for test tube families

  1. Liquid-Nitrogen Test for Blocked Tubes

    Science.gov (United States)

    Wagner, W. R.

    1984-01-01

    Nondestructive test identifies obstructed tube in array of parallel tubes. Trickle of liquid nitrogen allowed to flow through tube array until array accumulates substantial formation of frost from moisture in air. Flow stopped and warm air introduced into inlet manifold to heat tubes in array. Tubes still frosted after others defrosted identified as obstructed tubes. Applications include inspection of flow systems having parallel legs.

  2. Atmospheres in a Test Tube

    Science.gov (United States)

    Claudi, R.; Erculiani, M. S.; Giro, E.; D'Alessandro, M.; Galletta, G.

    2013-09-01

    The "Atmosphere in a Test Tube" project is a laboratory experiment that will be able to reproduce condition of extreme environments by means of a simulator. These conditions span from those existing inside some parts of the human body to combinations of temperatures, pressures, irradiation and atmospheric gases present on other planets. In this latter case the experiments to be performed will be useful as preliminary tests for both simulation of atmosphere of exoplanets and Solar System planets and Astrobiology experiments that should be performed by planetary landers or by instruments to be launched in the next years. In particular at INAF Astronomical Observatory of Padova Laboratory we are approaching the characterization of extrasolar planet atmospheres taking advantage by innovative laboratory experiments with a particular focus on low mass Neptunes and Super earths and low mass M dwarfs primaries.

  3. Tests of compressed geometry NEC acceleration tubes

    International Nuclear Information System (INIS)

    Raatz, J.E.; Rathmell, R.D.; Stelson, P.H.; Ziegler, N.F.

    1985-01-01

    Tests have been performed in the 3 MV Pelletron test machine at NEC on a compressed geometry tube which increases the insulating length of the tube by eliminating the heated electrode assemblies (approx.2.5 cm thick) at the end of each tube section. Some insert electrodes are changed to provide some trapping of secondary ions. The geometry tested provided an 18% increase in live ceramic in the tube. The compressed geometry tube allowed a terminal voltage of 3.55 MV on the 3 MV column at normal gradients of 30.3 kv/tube gap. The tube was also conditioned to more than 4 MV and remained stable in voltage with few sparks and with low x-ray levels for days at about 4 MV. This same performance could be achieved with or without arc discharge cleaning. 4 refs., 4 figs

  4. Atmosphere in a Test Tube

    Science.gov (United States)

    Claudi, R.; Pace, E.; Ciaravella, A.; Micela, G.; Piccioni, G.; Billi, D.; Cestelli Guidi, M.; Coccola, L.; Erculiani, M. S.; Fedel, M.; Galletta, G.; Giro, E.; La Rocca, N.; Morosinotto, T.; Poletto, L.; Schierano, D.; Stefani, S.

    The ancestor philosophers' dream of thousand of new world is finally realised: more than 1800 extrasolar planets have been discovered in the neighborhood of our Sun. Most of them are very different from those we used to know in our Solar System. Others orbit the Habitable Zone (HZ) of their parent stars. Space missions, as JWST and the very recently proposed ARIEL, or ground based instruments, like SPHERE@VLT, GPI@GEMINI and EPICS@ELT, have been proposed and built to measure the atmospheric transmission, reflection and emission spectra over a wide wavelength range of these new worlds. In order to interpret the spectra coming out by this new instrumentation, it is important to know in detail the optical characteristics of gases in the typical physical conditions of the planetary atmospheres and how those characteristics could be affected by radiation driven photochemical and bio-chemical reaction. Insights in this direction can be achieved from laboratory studies of simulated planetary atmosphere of different pressure and temperature conditions under the effects of radiation sources, used as proxies of different bands of the stellar emission. ''Atmosphere in a Test Tube'' is a collaboration among several Italian astronomical, biological and engineering institutes in order to share their experiencece in performing laboratory experiments on several items concerning extrasolar planet atmospheres.

  5. Eddy current tube testing unit

    International Nuclear Information System (INIS)

    Dufayet, J.P.; Duret, G.

    1975-01-01

    The unit described can check a wide variety of tubes in quick succession and its modular design gives it a high degree of versability. Suitably defined working conditions and specific fittings enable most of the faults encountered in the manufacture of a tube to be detected. By appropriate means of selection based on signal amplitude, phase and frequency analyses it is possible to adapt selection criteria to the seriousness of the different categories of defect [fr

  6. Non-destructive testing of tubes by electromagnetic processes

    International Nuclear Information System (INIS)

    Kowarski, A.

    1979-01-01

    This article reviews and assesses the non destructive testing techniques used for locating defects in tubes by electromagnetic processes. These form the basis of many testing devices, the diversity of which results from various factors: range of materials, methods of fabrication, specific defects of the product. There are two distinct main families of devices utilising two different principles: dispersion flow and Foucault currents [fr

  7. A new family of ceramic X-ray tubes

    International Nuclear Information System (INIS)

    Berger, E.; Reiprich, S.

    1976-01-01

    The construction and performance of a family of metal-ceramic X-ray tubes are described. Four of these incorporate slanting anodes and one a plane anode giving directional and omnidirectional radiation characteristics respectively. The particular advantages of these tubes are their compactness, low weight, flash-over immunity and high thermal and mechanical stress tolerance. (orig.) [de

  8. Internal ultrasonic testing of steam generator tubes

    International Nuclear Information System (INIS)

    Furlan, J.; Soleille, G.; Chalaye, H.

    1983-01-01

    The ''in situ'' inspection of steam generator tubes uses generally Foucault currents before starting and along its life. This inspection aims at searching cracks and corrosion defects. The Foucault current method is quite badly adapted to ''closed crack'' detection, for it doesn't introduce neither resistivity or magnetic permeability variation, or lack of matter. More, it is sensible to the magnetic properties of the tube itself and to its environment (tubular or support plates). It is why, this first systematic inspection has to be completed by an ultrasonic one allowing to bring new elements in the uncertain cases. A device with an internal probe has been developed. It ''lights'' the tube wall with the aid of a transducer of which beam reflects on a mirror. Operating conditions are the same as for Foucault current testing, that is to say the probe moves inside the tube without rotation of the device (bent parts are excluded) [fr

  9. Eddy current testing of heat exchangers tubes

    International Nuclear Information System (INIS)

    Gouez, J.F.; Rieusset, A.; Groix, F.

    An automatic system for Eddy Current testing of heat exchangers tubes of warships was developed. The advantages are an exposure of the controller limited at the time required to put in place the system and a reduced time of control [fr

  10. Of Slot Machines and Broken Test Tubes

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 19; Issue 5. Of Slot Machines and Broken Test Tubes. S Mahadevan. General Article Volume 19 Issue 5 May 2014 pp 395-405. Fulltext. Click here to view fulltext PDF. Permanent link: https://www.ias.ac.in/article/fulltext/reso/019/05/0395-0405. Keywords.

  11. Surveillance test of OWL-2 inpile tube

    International Nuclear Information System (INIS)

    Shimizu, Masatsugu; Itoh, Noboru

    1976-08-01

    A series of irradiation surveillance tests performed in integrity evaluation of an inpile tube for the test loop OWL-2 are described. Specimens were exposed to the neutron fluences from 1 x 10 20 to 3.4 x 10 21 n/cm 2 (>1 MeV), and subjected to post-irradiation tensile test at room temperature and service temperature 285 0 C. The strength increased and the ductility decreased with increasing neutron fluence. The reduction in fracture ductility due to neutron irradiation in the fluence range was insignificant, and the elongation of 33% was retained even for the maximum neutron fluence at 285 0 C. Little decrease of the ductility with fluence indicates that the tube would be in service for long time, ie to the integral fluence of 3.4 x 10 21 n/cm 2 . (auth.)

  12. Thin tube testing by eddy currents

    International Nuclear Information System (INIS)

    David, Bernard; Pigeon, Michel

    1981-01-01

    It is often necessary to define test conditions in eddy current testing, in consequence rules and laws allowing a rapid choice of these conditions are welcome. The similarity law, given by Forster, using the reduced frequency f/fg, allows extrapolation of results from an object to one another, if these two objects are similar (i.e. all their dimensions are proportional). In a particular case, often met, a law going further is given to describe, in a sole way, eddy current behaviour using the reduced frequency in all thin tubes (internal to external diameter ratio between 0.85 to 1). For instance working at f/fe=2 defines the same verification leading to identical results, whatever the nature, the diameter or the thickness may be, if the tubes are thin. A diagram is given and a slide-rule, based on this principle, has been realized [fr

  13. Stress corrosion testing of irradiated cladding tubes

    International Nuclear Information System (INIS)

    Lunde, L.; Olshausen, K.D.

    1980-01-01

    Samples from two fuel rods with different cladding have been stress corrosion tested by closed-end argon-iodine pressurization at 320 0 C. The fuel rods with stress relieved and recrystallized Zircaloy-2 had received burnups of 10.000 and 20.000 MWd/ton UO 2 , respectively. It was found that the SCC failure stress was unchanged or slightly higher for the irradiated than for the unirradiated control tubes. The tubes failed consistently in the end with the lowest irradiation dose. The diameter increase of the irradiated cladding during the test was 1.1% for the stress-relieved samples and 0.24% for the recrystallized samples. SEM examination revealed no major differences between irradiated and unirradiated cladding. A ''semi-ductile'' fracture zone in recrystallized material is described in some detail. (author)

  14. Disc-Donut-Tube wear test report, Phase I

    International Nuclear Information System (INIS)

    Kowal, K.; Knaus, S.E.

    1976-06-01

    The report describes a test program which simulated the wear-inducing conditions in the AI Prototype CRBR Steam Generator. This was accomplished by simulating the wear inducing loading and motion of a steam tube against ''disc-donut'' tube spacer plates. It was found that 2- 1 / 4 Cr-1 Mo tubes, wearing against 2- 1 / 4 Cr-l Mo tube spacer plates, seized and galled as deep as .017 inches. Inconel 718 tube spacer plates uniformly wore the tubes as deep as .012 in. Aluminum bronze inserts wore as deep as .003 inches into the tube

  15. Tube vibration in industrial size test heat exchanger

    International Nuclear Information System (INIS)

    Halle, H.; Wambsganss, M.W.

    1980-03-01

    Tube vibration data from tests of a specially built and instrumented, industrial-type, shell-and-tube heat exchanger are reported. The heat exchanger is nominally 0.6 m (2 ft) in dia and 3.7 m (12 ft) long. Both full tube and no-tubes-in-window bundles were tested for inlet/outlet nozzles of different sizes and with the tubes supported by seven, equally-spaced, single-segmental baffles. Prior to water flow testing, natural frequencies and damping of representative tubes were measured in air and water. Flow testing was accomplished by increasing the flow rates in stepwise fashion and also by sweeping through a selected range of flow rates. The primary variables measured and reported are tube accelerations and/or displacements and pressure drop through the bundle. Tests of the full tube bundle configuration revealed tube rattling to occur at intermediate flow rates, and fluidelastic instability, with resultant tube impacting, to occur when the flow rate exceeded a threshold level; principally, the four-span tubes were involved in the regions immediately adjacent to the baffle cut. For the range of flow rates tested, fluidelastic instability was not achieved in the no-tubes-in-window bundle; in this configuration the tubes are supported by all seven baffles and are, therefore, stiffer

  16. Chemical cleaning specification: few tube test model

    International Nuclear Information System (INIS)

    Hampton, L.V.; Simpson, J.L.

    1979-09-01

    The specification is for the waterside chemical cleaning of the 2 1/4 Cr - 1 Mo steel steam generator tubes. It describes the reagents and conditions for post-chemical cleaning passivation of the evaporator tubes

  17. Maintenance of immersion ultrasonic testing on the water tube boiler

    International Nuclear Information System (INIS)

    Ishiyama, Toru; Kawasaki, Ichio; Miura, Hirohito

    2014-01-01

    There are 4-boiler in nuclear fuel cycle engineering laboratories (NCL). These boilers have been operated in the long term over 20 years. One of them, the leakage of boiler water was found at one of the generating tubes, and 2 adjoining generating tubes were corroded in Dec, 2011. These generating tubes were investigated by immersion ultrasonic testing (UT) for measure thickness of the tube. As a result, thinner tube was found in a part of a bend and near the water drum. These parts are covered with sulfide deposit, it seems that the generating tubes were corroded by sulfide. (author)

  18. Test Station for Measuring Aluminum Tube Geometrical Parameters

    CERN Document Server

    Oansea, D; Gongadze, A L; Gostkin, M I; Dedovich, D V; Evtoukhovitch, P G; Comanescu, B; Kotov, S A; Necsoiu, T; Potrap, I N; Rogalev, E V; Tskhadadze, E G; Chelkov, G A

    2001-01-01

    A test station for quality control of aluminum tube outer diameter and wall thickness is presented. The tested tubes are used for drift detector assembly of ATLAS (LHC, CERN) muon system. The outer diameter and wall thickness of aluminium tubes are measured by means of noncontact optical and ultrasonic methods respectively with the accuracy of 3 {\\mu}m. The testing process is automatic and interacts with the production data base.

  19. Multifrequency eddy current testing of helical tubes of steam generators

    International Nuclear Information System (INIS)

    Pigeon, M.; David, B.

    1983-06-01

    In the event of a water-sodium reaction in a steam-generator of a fast breeder reactor, it is necessary to test the tubes close to the leak to evaluate the damage. In SUPERPHENIX, the tubes are about 100m long and are coiled on a dead body. This report describes the equipment and the technic to test such tubes with multifrequency eddy current technics [fr

  20. Test tube systems with cutting/recombination operations

    Energy Technology Data Exchange (ETDEWEB)

    Freund, R. [Technische Universitaet Wien (Austria); Csuhaj-Varju, E. [Computer and Automation Institute, Budapest (Hungary); Wachtler, F. [Universitaet Wien (Austria)

    1996-12-31

    We introduce test tube systems based on operations that are closely related to the splicing operations, i.e. we consider the operations of cutting a string at a specific site into two pieces with marking them at the cut ends and of recombining two strings with specifically marked endings. Whereas in the splicing of two strings these strings are cut at specific sites and the cut pieces are recombined immediately in a crosswise way, in CR(cutting/recombination)-schemes cutting can happen independently from recombining the cut pieces. Test tube systems based on these operations of cutting and recombination turn out to have maximal generative power even if only very restricted types of input filters for the test tubes are used for the redistribution of the contents of the test tubes after a period of cuttings and recombinations in the test tubes. 10 refs.

  1. Characterization of Friction Stir Welded Tubes by Means of Tube Bulge Test

    International Nuclear Information System (INIS)

    D'Urso, G.; Longo, M.; Giardini, C.

    2011-01-01

    Mechanical properties of friction stir welded joints are generally evaluated by means of conventional tensile test. This testing method might provide insufficient information because maximum strain obtained in tensile test before necking is small; moreover, the application of tensile test is limited when the joint path is not linear or even when the welds are executed on curved surfaces. Therefore, in some cases, it would be preferable to obtain the joints properties from other testing methods. Tube bulge test can be a valid solution for testing circumferential or longitudinal welds executed on tubular workpieces. The present work investigates the mechanical properties and the formability of friction stir welded tubes by means of tube bulge tests. The experimental campaign was performed on tubular specimens having a thickness of 3 mm and an external diameter of 40 mm, obtained starting from two semi-tubes longitudinally friction stir welded. The first step, regarding the fabrication of tubes, was performed combining a conventional forming process and friction stir welding. Sheets in Al-Mg-Si-Cu alloy AA6060 T6 were adopted for this purpose. Plates having a dimension of 225x60 mm were bent (with a bending axis parallel to the main dimension) in order to obtain semi-tubes. A particular care was devoted to the fabrication of forming devices (punch and die) in order to minimize the springback effects. Semi-tubes were then friction stir welded by means of a CNC machine tool. Some preliminary tests were carried out by varying the welding parameters, namely feed rate and rotational speed. A very simple tool having flat shoulder and cylindrical pin was used. The second step of the research was based on testing the welded tubes by means of tube bulge test. A specific equipment having axial actuators with a conical shape was adopted for this study. Some analyses were carried out on the tubes bulged up to a certain pressure level. In particular, the burst pressure and the

  2. Eddy current testing of steam generator tubes

    International Nuclear Information System (INIS)

    Neumaier, P.

    1981-01-01

    A rotating probe is described for improving the inspection of tubes and end plate in steam generators. The method allows a representation of the whole defect, consequently the observer is able to determine directly the type of defect, signal processing in-line or off-line is possible [fr

  3. Automatic integrated testing bench for tubes in translation

    International Nuclear Information System (INIS)

    Dufayet, J.P.; Perdijon, J.

    1976-01-01

    All the nondestructive tests required for receiving the cladding tubes intended for fast nuclear reactor are integrated on this bench: quality control by eddy currents and ultra-sounds, thickness and (inner and outer) diameter measurement. The linear displacement of the tube allows very high rates to be attained [fr

  4. Life-test results on the Zetatron tube, transformer and the tube-transformer assembly

    International Nuclear Information System (INIS)

    Shope, L.A.

    1983-01-01

    In the development of the PFN probe it became evident that some considerable life testing of the neutron tube, high-voltage pulse transformer, and the tube-transformer assembly (TTA) were needed to (1) identify life limiting mechanisms, (2) estimate performance degradation, and (3) provide a data base for end-of-life predictions. Initial results had shown clearly that testing monitored by technicians would be much too costly. Consequently, a computer-controlled and monitored test was developed. This paper describes the test, summarizes the records, and discusses the results. Also presented are early results of actual probe life testing now underway

  5. Investigation into the suitability of capillary tubes for microcrystalline testing.

    Science.gov (United States)

    Elie, Leonie E; Baron, Mark G; Croxton, Ruth S; Elie, Mathieu P

    2013-07-01

    A comparison between microcrystalline tests performed on microscope slides and flat capillary tubes with inner diameters ranging from 0.1 to 0.7 mm was carried out to explore the appropriateness of tubes for rapid testing of suspected drugs of abuse in the laboratory as well as in the field. Tests for mephedrone, cocaine, and phencyclidine were chosen as examples to investigate the handling of the capillary tubes, the influence on crystal habit, size, and the effects on the limit of detection. Image stacking software was used to increase the depth of field of micrographs taken from developed microcrystals greatly enhancing the interpretability even months after carrying out the microcrystalline test. Additionally, the potential of seeding capillary tubes with a reagent was studied. Pre-treatment of tubes would allow microcrystalline tests to be carried out quicker and anywhere without the necessity of taking along expensive and hazardous reagents. The sealing of capillary tubes containing developed microcrystalline tests in order to preserve results for a long period of time was successfully done by applying paraffin wax to the open ends. Finally, it was concluded that capillary tubes are suitable vessels for performing microcrystalline tests. The increased portability of the improved set-up allows tests to be safely executed outside laboratories without impairing the quality of the result. Findings were applied to six legal high samples purchased online between May and August 2011. The active ingredients like MDAI as well as cutting agents like caffeine were successfully identified using the microcrystalline test technique in capillary tubes. Copyright © 2012 John Wiley & Sons, Ltd.

  6. Statistics applied to the testing of cladding tubes

    International Nuclear Information System (INIS)

    Perdijon, J.

    1987-01-01

    Cladding tubes, either steel or zircaloy, are generally given a 100 % inspection through ultrasonic non-destructive testing. This inspection may be completed beneficially with an eddy current test, as this is not sensitive to the same defects as those typically traced by ultrasonic testing. Unfortunately, the two methods (as with other non-destructive tests) exhibit poor precision; this means that a flaw, whose size is close to that denoted as rejection limit, may be accepted or rejected. Currently, rejection, i.e. the measurement above which a tube is rejected, is generally determined through measuring a calibration tube at regular time intervals, and the signal of a given tube is compared to that of the most recently completed calibration. This measurement is thus subject to variations which can be attributed to an actual shift of adjustments as well as to poor precision. For this reason, monitoring instrument adjustments using the so-called control chart method are proposed

  7. No rotating U.S. Testing of thin walled tubes

    International Nuclear Information System (INIS)

    Furlan, J.; Boulanger, G.; Mogavero, R.

    1981-07-01

    Thin walled tube ultrasonic testing is performed, with Lamb waves, using annular transducers and conical or helicoidal mirrors. The main advantage of this already known system is dispensing with rotation of tube and/or transducer. High speed control (30 cm/s and more) is then allowed. The present paper describes the parameters influencing the sensitivity has been improved by searching, theoretically and practically, the best suited Lamb wave modes, and by using transducers which are well characterized. Practical example of cladding tube U.S. testing is described

  8. Testing and analysis of tube voltage and tube current in the radiation generator for mammography

    International Nuclear Information System (INIS)

    Jung, Hong Ryang; Hong, Dong Hee; Han, Beom Hui

    2014-01-01

    Breast shooting performance management and quality control of the generator is applied to the amount of current IEC(International Electrotechnical Commission) 60601-2-45 tube voltage and tube current are based on standards that were proposed in the analysis of the test results were as follows. Tube voltage according to the value of the standard deviation by year of manufacture from 2001 to 2010 as a 42-3.15 showed the most significant, according to the year of manufacture by tube amperage value of the standard deviation to 6.38 in the pre-2000 showed the most significant , manufactured after 2011 the standard deviation of the devices, the PAE(Percent Average Error) was relatively low. This latest generation device was manufactured in the breast of the tube voltage and tube diagnosed shooting the correct amount of current to maintain the performance that can be seen. The results of this study as the basis for radiography diagnosed breast caused by using the device's performance and maintain quality control, so the current Food and Drug Administration 'about the safety of diagnostic radiation generator rule' specified in the test cycle during three years of self-inspection radiation on a radiation generating device ensure safety and performance of the device using a coherent X-ray(constancy) by two ultimately able to keep the radiation dose to the public to reduce the expected effect is expected

  9. Sodium flow distribution test of the air cooler tubes

    International Nuclear Information System (INIS)

    Uchida, Hiroyuki; Ohta, Hidehisa; Shimazu, Hisashi

    1980-01-01

    In the heat transfer tubes of the air cooler which is installed in the auxiliary core cooling system of the fast breeder prototype plant reactor ''Monju'', sodium freezing may be caused by undercooling the sodium induced by an extremely unbalanced sodium flow in the tubes. Thus, the sodium flow distribution test of the air cooler tubes was performed to examine the flow distribution of the tubes and to estimate the possibility of sodium freezing in the tubes. This test was performed by using a one fourth air cooler model installed in the water flow test facility. As the test results show, the flow distribution from the inlet header to each tube is almost equal at any operating condition, that is, the velocity deviation from normalized mean velocity is less than 6% and sodium freezing does not occur up to 250% air velocity deviation at stand-by condition. It was clear that the proposed air cooler design for the ''Monju'' will have a good sodium flow distribution at any operating condition. (author)

  10. Development and test evaluation of duplex steam reformer tube

    International Nuclear Information System (INIS)

    Allen, D.C.; Meyer, D.J.; Pflasterer, G.R.

    1980-01-01

    For HTR applications involving a steam reformer (SR), it is uncertain whether an intermediate heat exchanger (IHX) is required. There are several system configurations that could be developed for the application of nuclear heat using the steam reformer reaction. The considerations (advantages vs. disadvantages) for each of the system configurations are summarized. The approach that technically and economically appears to be the most attractive, in studies conducted by General Electric, combines the SR process heat exchanger and the IHX in a single component using a duplex tube. A central question concerning the duplex tube concept is whether the design would provide adequate leak monitoring capability and significant reduction in tritium and hydrogen diffusion, while introducing only a small increase in overall temperature difference from the helium to the process gas. A cooperative GE-KFA effort was undertaken to develop, fabricate, test, and evaluate a duplex steam reformer tube. GE was responsible for the development and fabrication of the tube, and KFA was responsible for testing the tube in the EVA I facility at Juelich. Both GE and KFA are evaluating the thermochemical and metallurgical test data. Actual fabrication of the tube was performed by Foster-Wheeler in accordance with the GE design. This paper reviews the highlights of the fabrication development and preliminary evaluation of the test data

  11. Family Experiences With Feeding Tubes in Neurologic Impairment: A Systematic Review.

    Science.gov (United States)

    Nelson, Katherine E; Lacombe-Duncan, Ashley; Cohen, Eyal; Nicholas, David B; Rosella, Laura C; Guttmann, Astrid; Mahant, Sanjay

    2015-07-01

    Gastrostomy tubes (G-tubes) are frequently used to provide enteral nutrition for children who have neurologic impairment. Understanding the impact of G-tubes from the family's perspective will inform decision-making and improve support from health care providers. This study explored the experiences of families after G-tube placement in children with neurologic impairment. We conducted a systematic review of English-language qualitative primary research studies describing family experiences after G-tube placement. Six electronic databases were searched from inception to June 2014. Two authors independently screened and identified relevant studies, evaluated quality of reporting by using the Consolidated Criteria for Reporting Qualitative Research tool, and extracted data. Overarching concepts were developed by using thematic analysis. From 2674 screened abstracts, 84 texts were reviewed, and 13 studies met the inclusion criteria. G-tubes affect the lives of children, parents, and the family unit in many ways, both positive and negative. Improvements and challenges were described for children's health and happiness, for parental caregiving and stress, and for logistics and bonding within the family. G-tube feeding also changed relationships within the family, between the family and the medical system, and between the family and the outside world. Furthermore, experiences varied, with different families framing similar concepts as positive and negative. G-tube placement has diverse effects on daily life for children with neurologic impairment and their families. Clinicians may use the themes identified in this study to guide conversations with families about their values, experiences, and expectations before and after G-tube placement. Copyright © 2015 by the American Academy of Pediatrics.

  12. Remote field eddy current testing of ferromagnetic tubes

    International Nuclear Information System (INIS)

    David, B.

    1990-01-01

    In order to test ferromagnetic tubes using internal probes, Intercontrole and the CEA have carried out theoretical and experimental works and developed a method to adapt the Remote Field Eddy Current technique which has been known and used for 30 years now. This document briefly recalls the basic principles of the Remote Field Eddy Current technique, the various steps of the works carried out and mainly describes examples of field inspection of ferromagnetic tubes and pipes [fr

  13. Influence of test tube material on subcooled flow boiling critical heat flux in short vertical tube

    International Nuclear Information System (INIS)

    Hata, Koichi; Shiotsu, Masahiro; Noda, Nobuaki

    2007-01-01

    The steady state subcooled flow boiling critical heat flux (CHF) for the flow velocities (u=4.0 to 13.3 m/s), the inlet subcoolings (ΔT sub,in =48.6 to 154.7 K), the inlet pressure (P in =735.2 to 969.0 kPa) and the increasing heat input (Q 0 exp(t/τ), τ=10, 20 and 33.3 s) are systematically measured with the experimental water loop. The 304 Stainless Steel (SUS304) test tube of inner diameter (d=6 mm), heated length (L=66 mm) and L/d=11 with the inner surface of rough finished (Surface roughness, Ra=3.18 μm), the Cupro Nickel (Cu-Ni 30%) test tube of d=6 mm, L=60 mm and L/d=10 with Ra=0.18 μm and the Platinum (Pt) test tubes of d=3 and 6 mm, L=66.5 and 69.6 mm, and L/d=22.2 and 11.6 respectively with Ra=0.45 μm are used in this work. The CHF data for the SUS304, Cu-Ni 30% and Pt test tubes were compared with SUS304 ones for the wide ranges of d and L/d previously obtained and the values calculated by the authors' published steady state CHF correlations against outlet and inlet subcoolings. The influence of the test tube material on CHF is investigated into details and the dominant mechanism of subcooled flow boiling critical heat flux is discussed. (author)

  14. Influence of Test Tube Material on Subcooled Flow Boiling Critical Heat Flux in Short Vertical Tube

    International Nuclear Information System (INIS)

    Koichi Hata; Masahiro Shiotsu; Nobuaki Noda

    2006-01-01

    The steady state subcooled flow boiling critical heat flux (CHF) for the flow velocities (u = 4.0 to 13.3 m/s), the inlet subcooling (ΔT sub,in = 48.6 to 154.7 K), the inlet pressure (P in = 735.2 to 969.0 kPa) and the increasing heat input (Q 0 exp(t/t), t = 10, 20 and 33.3 s) are systematically measured with the experimental water loop. The 304 Stainless Steel (SUS304) test tubes of inner diameters (d = 6 mm), heated lengths (L = 66 mm) and L/d = 11 with the inner surface of rough finished (Surface roughness, R a = 3.18 μm), the Cupro Nickel (Cu-Ni 30%) test tubes of d = 6 mm, L = 60 mm and L/d = 10 with R a = 0.18 μm and the Platinum (Pt) test tubes of d = 3 and 6 mm, L = 66.5 and 69.6 mm, and L/d 22.2 and 11.6 respectively with R a = 0.45 μm are used in this work. The CHF data for the SUS304, Cu-Ni 30% and Pt test tubes were compared with SUS304 ones for the wide ranges of d and L/d previously obtained and the values calculated by the authors' published steady state CHF correlations against outlet and inlet subcooling. The influence of the test tube material on CHF is investigated into details and the dominant mechanism of subcooled flow boiling critical heat flux is discussed. (authors)

  15. Nondestructive testing of multi-layer tubes during fabrication

    International Nuclear Information System (INIS)

    Troitskij, V.A.; Biletskij, S.M.; Trushchenko, A.A.

    1985-01-01

    Design of multilayer steel tubes for gas pipelines and technology of their fabrication are described in brief. Testing of the ground metal and welded joints of tubes used in their fabrication are considered. These methods comprise ultrasonic (US) testing of band, US testing and vacuum-bubble testing (VBT) of inner lap joints of shells X-ray TV control (XTVC) of ring welds, US testing of edge sections of shells with a continuous wall. Equipment applied in testing is described. XTVC is exercised by means of the RUP-150/300-10 X-ray apparatus, RI-60TEh introscope, sensitivity of testing is not worse than 4%, the rate equals 1-2 m/min

  16. A blind test on the pulse tube refrigerator model (PTRM)

    International Nuclear Information System (INIS)

    Yuan, S.W.K.; Radebaugh, R.

    1996-01-01

    The Stirling Refrigerator Performance Model (SRPM) has been validated extensively against the Lockheed built Stirling Coolers and various units in the literature. This model has been modified to predict the performance of the Pulse Tube Coolers (PTCs). It was successfully validated against a Lockheed in-house-built PTC. The results are to be published elsewhere. In this paper, the validation of PTRM against a NIST (National Institute of Standards and Technology) orifice pulse tube cooler is reported. Dimensions and operating condition of the PTC were obtained from NIST without prior knowledge of the performance. In other words, this is a open-quote blind test close-quote on the PTRM with the help of the National Institute of Standards and Technology. Good correlation was found between the test data and the prediction. PTRM is a generic model that gives accurate performance prediction of the pulse tube coolers

  17. Delayed hydrogen cracking test design for pressure tubes

    International Nuclear Information System (INIS)

    Haddad, Roberto; Loberse, Antonio N.; Yawny, Alejandro A.; Riquelme, Pablo

    1999-01-01

    CANDU nuclear power stations pressure tubes of alloy Zr-2,5 % Nb present a cracking phenomenon known as delayed hydrogen cracking (DHC). This is a brittle fracture of zirconium hydrides that are developed by hydrogen due to aqueous corrosion on the metal surface. This hydrogen diffuses to the crack tip where brittle zirconium hydrides develops and promotes the crack propagation. A direct current potential decay (DCPD) technique has been developed to measure crack propagation rates on compact test (CT) samples machined from a non irradiated pressure tube. Those test samples were hydrogen charged by cathodic polarization in an acid solution and then pre cracked in a fatigue machine. This technique proved to be useful to measure crack propagation rates with at least 1% accuracy for DHC in pressure tubes. (author)

  18. Tube suction test for evaluating durability of cementitiously stabilized soils.

    Science.gov (United States)

    2011-06-01

    In a comprehensive laboratory study, different tests namely, unconfined compressive strength (UCS) at the end of freeze-thaw/wet-dry (F-T/W-D) cycles, resilient modulus (Mr) at the end of F-T/W-D cycles, vacuum saturation, tube suction, and moisture ...

  19. Tube suction test for evaluating durability of cementitiously stabilized soils.

    Science.gov (United States)

    2011-06-01

    In a comprehensive laboratory study, different tests namely, unconfined compressive strength (UCS) at the end of freeze-thaw/wet-dry (FT/ : W-D) cycles, resilient modulus (Mr) at the end of F-T/W-D cycles, vacuum saturation, tube suction, and moistur...

  20. Optimization of ultrasonic tube testing with concentric transducers

    International Nuclear Information System (INIS)

    Dufayet, J.-P.; Gambin, Raymond.

    1978-01-01

    In order to test tubes by ultrasonics without rotation, concentric transducers can be used with conical mirrors to detect transverse defects and with helical shaped mirrors to detect longitudinal defects. Further optimization studies have been carried out in order to bring the system highly operational. The respective advantages brought by the rotating screen or by our especially designed sectorial transducers are discussed [fr

  1. Eddy current test of fin tubes for a heat exchanger

    International Nuclear Information System (INIS)

    KIm, Young Joo; Lee, Se Kyung; Chung, Min Hwa

    1992-01-01

    Eddy current probes were designed for the test of fin tubes. Fin tubes, often used for heat exchangers, have uneven outer and inner surfaces to enhance the heat emission. The surface roughness make it difficult to detect flaws employing eddy current test(ECT). In order to overcome the difficulties we performed two types of works, one is the delopment of ECT probes, and the other is the signal processing including fast Fourier transform and digital filtering. In the development of ECT probes, we adopted empirical design method. Our ECT probes for fin tubes are inside diameter type. And we are specially concerned about geometric features such as the widths of the coils composing an ECT probe. We fabricated four probes with various coil widths. Eddy current test was performed using those ECT probes on specimens with artificial flaws. After analyzing the output signals, we found that, in order for the effective testing, the width of a coil should be determined considering the pitch of the fins of a tube. And we also learned that the frequency filtering could improve the s/n ratio.

  2. Inert medium (helium) irradiation testing of pressure tube samples

    International Nuclear Information System (INIS)

    Ancuta, M.; Radu, V.; Stefan, V.; Preda, M.

    2001-01-01

    Irradiation tests currently performed in C-5 capsule aim at obtaining data and information concerning behavior to irradiation of pressure tubes of CANDU type fuel channel, to evidence the factors limiting operation life span. A calculation code for analysis and prediction of pressure tube behavior should be based upon periodical inspection results, post irradiation examination of the removed from reactor pressure tubes as well as on the experimental results obtained with materials subjected to irradiation conditions identical with the operational ones. Mechanical behavior analysis should focus both complex thermal-mechanical type stresses and mechanical properties alteration under irradiation. The experimental results should be applied: - to evaluate the irradiation effects upon mechanical properties of Zr-2.5% Nb exposed to fluences up to 10 21 n·cm -2 ; - to gather data concerning the real stress / real deformation characteristic from which characteristic quantities can be deduced as, for instance, elasticity modulus, plasticity modulus, exponent of stress term in the Tsu-Berteles relation, to be used within the CANTUP simulation code describing pressure tube behavior, currently developed at INR Pitesti; - to develop prediction methods of pressure tube behavior and merging with in-service inspection procedure in order to forecast the life span and the proper timing for replacement before major failures occur. The samples irradiated in C-5 capsule were extracted from the ends of Zr-2.5% Nb pressure tubes resulting from Cernavoda NPP Unit 1. The samples for tensile tests were extracted on longitudinal and transversal directions of the pressure tube. The tests were carried out under following conditions: - test environment temperature, 260 - 280 deg.C; - testing medium, helium at 1 - 6 b pressure; - neutron flux (E n > 1 MeV), 1 - 2 · 10 13 ncm -2 s -1 ; - neutron fluence (E n > 1 MeV), 4 · 10 20 ncm -2 . The following characteristics were obtained from tensile

  3. SCC testing of steam generator tubes repaired by welded sleeves

    International Nuclear Information System (INIS)

    Pierson, E.; Stubbe, J.

    1993-01-01

    One way to repair steam generator tubing is to introduce a sleeve inside the tube so that it spans the corroded area and to seal it at both ends. This technique has been studied at Laborelec with a particular attention paid to the occurrence of new SCC cracks at the upper joint. Tube segments coming from the same lot of mill annealed alloy 600 were sent to six manufacturers to be sleeved by their own procedure (including TIG, laser or kinetic welding, followed or not by a stress relief heat treatment), and then tested at Laborelecin 10% NaOH at 350 degrees C. The tests were performed with and without differential pressure i.e. in capsules (Δ = 9 and 19 MPa) and in autoclave (Δp = 0). Nearly all the not stress relieved mock-ups developed through cracks in several hundred hours in auto-clave. The cracks were circumferential and situated near the weld. At 9 and 19 MPa, the time to failure decreased and longitudinal cracks appeared near the weld and at the transition zone of expanded areas. Cracks were never observed in the alloy 690 sleeve, except in the weld bead. Reference capsules (roll expaned tubes) made of the same lot of alloy 600 were tested in the same environment

  4. Preliminary project of installation for separation tubes tests-ITTS

    International Nuclear Information System (INIS)

    Rocha, Z.

    1984-01-01

    A consolidation of actual ideas about installation, entitled ''Installation to separation tubes tests-ITTS'', expected to CDTN is presented. The project bases, the testing to be realized, the procedures to be obeyed during the operation, the components and the space required by installation and auxiliary equipments, the presumable origin of components (nacional and international), including a preliminary list of building and operation costs are described. (author) [pt

  5. Fracture Toughness Round Robin Test International in pressure tube materials

    International Nuclear Information System (INIS)

    Villagarcia, M.P.; Liendo, M.F.

    1993-01-01

    Part of the pressure tubes surveillance program of CANDU type reactors is to determine the fracture toughness using a special fracture specimen and test procedure. Atomic Energy of Canada Limited decided to hold a Round Robin Test International and 9 laboratories participated worldwide in which several pressure tube materials were selected: Zircaloy-2, Zr-2.5%Nb cold worked and Zr-2.5%Nb heat treated. The small specimens used held back the thickness and curvature of the tube. J-R curves at room temperature were obtained and the crack extension values were determined by electrical potential drop techniques. These values were compared with results generated from other laboratories and a bid scatter was founded. It could be due to slight variations in the test method or inhomogeneity of the materials and a statistical study must be done to see if there is any pattern. The next step for the Round Robin Test would be to make some modifications in the test method in order to reduce the scatter. (Author)

  6. RIA simulation tests using driver tube for ATF cladding

    Energy Technology Data Exchange (ETDEWEB)

    Cinbiz, Mahmut N. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Brown, N. R. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Lowden, R. R. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Linton, K. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Terrani, K. A. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2017-07-01

    Pellet-cladding mechanical interaction (PCMI) is a potential failure mechanism for accident-tolerant fuel (ATF) cladding candidates during a reactivity-initiated accident (RIA). This report summarizes Fiscal Year (FY) 2017 research activities that were undertaken to evaluate the PCMI-like hoop-strain-driven mechanical response of ATF cladding candidates. To achieve various RIA-like conditions, a modified-burst test (MBT) device was developed to produce different mechanical pulses. The calibration of the MBT instrument was accomplished by performing mechanical tests on unirradiated Generation-I iron-chromium-aluminum (FeCrAl) alloy samples. Shakedown tests were also conducted in both FY 2016 and FY 2017 using unirradiated hydrided ZIRLO™ tube samples. This milestone report focuses on testing of ATF materials, but the benchmark tests with hydrided ZIRLO™ tube samples are documented in a recent journal article.a For the calibration and benchmark tests, the hoop strain was monitored using strain gauges attached to the sample surface in the hoop direction. A novel digital image correlation (DIC) system composed of a single high-speed camera and an array of six mirrors was developed for the MBT instrument to better resolve the failure behavior of samples and to provide useful data for validation of high-fidelity modeling and simulation tools. The DIC system enable a 360° view of a sample’s outer surface. This feature was added to the instrument to determine the precise failure location on a sample’s surface for strain predictions. The DIC system was tested on several silicon carbide fiber/silicon carbide matrix (SiC/SiC) composite tube samples at various pressurization rates of the driver tube (which correspond to the strain rates for the samples). The hoop strains for various loading conditions were determined for the SiC/SiC composite tube samples. Future work is planned to enhance understanding of the failure behavior of the ATF cladding candidates of age

  7. A novel test tube method of screening for hemoglobin E.

    Science.gov (United States)

    Tatu, T; Kasinrerk, W

    2012-02-01

    Hemoglobin (Hb) E is a β-structural variant common worldwide. This Hb disorder can form a compound heterozygous state with the β-thalassemia gene, leading to life-threatening hereditary hemolytic anemia, HbE/β-thalassemia. Screening of HbE has proven to be a challenging practice in prevention and control of the HbE/β-thalassemia. A novel test tube method for HbE screening using diethyl aminoethyl (DEAE)-cellulose resin was described. With the developed system, HbE/A(2) did not bind to the resin and remained dissolved in the supernatant, whereas other Hbs completely bound to the resin. The red color of the supernatant observed in the test tube indicated the presence of HbE. Colorless or markedly pale color of the supernatant indicates the absence of HbE. Accuracy and efficiency of the established method in detecting HbE was comparable with the standard cellulose acetate electrophoresis method. The developed method is cheap and simple with no requirement of sophisticated equipment. The reagent could be stored at 4 °C for up to 5 months. Hemolysate samples aged up to 5 months were still suitable for this test. The described novel test tube method could be an alternative method of mass population screening for HbE, particularly in small health care facilities. © 2011 Blackwell Publishing Ltd.

  8. Failure analysis of burst tested fuel tube samples

    International Nuclear Information System (INIS)

    Padmaprabu, C.; Ramana Rao, S.V.; Srivatsava, R.K.

    2005-01-01

    The Total Circumferential Elongation (TCE) is an important parameter for evaluation of ductility of the Zircaloy-4 fuel tubes for the PHWR reactors. The TCE values of the fuel tubes were obtained using the burst testing technique. In some lots there is a variation in the values of the TCE. To investigate the reasons for such a large variation in the TCE, samples were selected at appropriate intervals and sectioned at the fractured portion. The surface morphology of the fractured surfaces was examined under Scanning Electron Microscope (SEM) equipped with Energy Dispersive Spectrometer (EDS). The morphologies show segregation of elements at specific locations. Energy dispersive spectra was obtained from those segregated particles. According to the magnitude of TCE value the samples were classified into low, intermediate and high ductility. Low ductility samples were found to contain large amount of segregations along the thickness direction of the tube. This forms a brittle region and a path for the easy crack growth along thickness direction. In the case of intermediate samples the segregation occurred in fewer locations compared to low ductile samples and also confined to the circumferential direction of the outside surface of the tube. Due to this, probability of crack formation at the surface of the tube could be high. But crack growth would be slower in the ductile matrix along the thickness direction resulting in the enhancement of TCE value compared to the low ductile sample. In the high ductile samples, the segregations were very scarce and found to be isolated and embedded in the ductile matrix. The mode of failure in these types of samples was found to be purely ductile. Cracks were found to originate solely from the micro voids in the material. As the probability of crack formation and its propagation is low, very high TCE values were observed in these samples. Microstructural observations of fractured surfaces and EDAX analysis was able to identify the

  9. Eddy current testing device for metallic tubes at least locally curved

    International Nuclear Information System (INIS)

    Pigeon, Marcel; Vienot, Claude.

    1975-01-01

    Steam generators, condensers and heat exchangers generally consist of metallic tube bundles, the tubes having a complex geometry. The invention concerns an Eddy current testing device for metallic tubes at least locally curved, operating by translation of a probe inside the tubes [fr

  10. Field tests of 2- and 40-tube condensers at the East Mesa Geothermal Test Site

    Energy Technology Data Exchange (ETDEWEB)

    Murphy, R.W.; Domingo, N.

    1982-05-01

    Two water-cooled isobutane condensers, one with 2 tubes and one with 40 tubes, were subjected to field tests at the East Mesa Geothermal Test Site to assess relative heat transfer performance in both surface evaporator and direct-contact evaporator modes. The five groups of tests established that field performance was below earlier laboratory-determined levels and that direct-contact evaporator mode performance was poorer than that for the surface evaporator mode. In all test situations, fluted condenser tubes performed better than smooth condenser tubes. Cooling water quality had no significant effect on performance, but brine preflash in the direct-contact mode did promote some relative performance improvement. Important implications of these results for binary geothermal power plants are that (1) working-fluid-side impurities can significantly degrade heat transfer performance of the power plant condensers and (2) provisions for minimizing such impurities may be required.

  11. Tests and analysis on steam generator tube failure propagation

    International Nuclear Information System (INIS)

    Tanabe, Hiromi

    1990-01-01

    The understanding of leak enlargement and failure propagation behavior is essential to select a design basis leak (DBL) of LMFBR steam generators. Therefore, various series of experiments, such as self-enlargement tests, target wastage tests, failure propagation tests were conducted in a wide range of leak using test facilities of SWAT at PNC/OEC. Especially, in the large leak tests, potential of overheating failure was investigated under a prototypical steam cooling condition inside target tubes. In the small leak, the difference of wastage resistivity was clarified among several tube materials such as 9-chrome steels. In regard to an analytical approach, a computer code LEAP (Leak Enlargement and Propagation) was developed on the basis of all of these experimental results. The code was used to validate the previously selected DBL of the prototype reactor, Monju, steam generator. This approach proved to be successful in spite of somewhat over-conservatism in the analysis. Moreover, LEAP clarified the effectiveness of a rapid steam dump and an enhanced leak detection system. The code improvement toward a realistic analysis is desired, however, to lessen the DBL for a future large plant and then the re-evaluation of the experimental data such as the size of secondary failure is under way. (author). 4 refs, 8 figs, 1 tab

  12. Counting DNA: estimating the complexity of a test tube of DNA.

    Science.gov (United States)

    Faulhammer, D; Lipton, R J; Landweber, L F

    1999-10-01

    We consider the problem of estimation of the 'complexity' of a test tube of DNA. The complexity of a test tube is the number of different kinds of strands of DNA in the test tube. It is quite easy to estimate the number of total strands in a test tube, especially if the strands are all the same length. Estimation of the complexity is much less clear. We propose a simple kind of DNA computation that can estimate the complexity.

  13. Geometric Relations for CYLEX Test Tube-Wall Motion

    Science.gov (United States)

    Hill, Larry

    2015-06-01

    The CYLinder EXpansion (CYLEX) test is a (precision, instrumented, high-purity annealed copper) pipe bomb. Its essential measured quantities are detonation speed and tube-wall motion. Its main purpose is to calibrate detonation product equations of state (EOS) by measuring how product fluid pushes metal. In its full complexity, CYLEX is an integral test, for which EOS calibration requires the entire system to be computationally modeled and compared to salient data. Stripped to its essence, CYLEX is a non-integral test for which one may perform the inverse problem, to infer the EOS directly from data. CYLEX analysis can be simplified by the fact that the test constituents achieve a steady traveling wave structure; this allows derivation of several useful geometric relationships regarding tube wall motion. The first such treatment was by G.I. Taylor. Although his analysis was limited to small wall deflection angles, he asserted that the results remain valid for arbitrary ones. I confirm this attribute and present additional useful relationships. In the past decade, CYLEX wall-motion instrumentation has migrated almost entirely from streak camera to PDV, yet discrepancies remain between the two methods. I further present geometric relationships that shed light on this issue. Work supported by the U.S. DOE.

  14. Instruments for non-destructive evaluation of advanced test reactor inpile tubes

    International Nuclear Information System (INIS)

    Livingston, R.A.; Beller, L.S.; Edgett, S.M.

    1986-01-01

    The Advanced Test Reactor is a 250 MW LWR used primarily for irradiation testing of materials contained in inpile tubes that pass through the reactor core. These tubes provided the high pressure and temperature water environment required for the test specimens. The reactor cooling water surrounding the inpile tubes is at much lower pressure and temperature. The structural integrity of the inpile tubes is monitored by routine surveillance to ensure against unplanned reactor shutdowns to replace defective inpile tubes. The improved instruments developed for inpile tube surveillance include a bore profilometer, ultrasonic flaw detetion system and bore diameter gauges. The design and function of these improved instruments is presented

  15. Development of a sealing process of capsules for surveillance test tubes of the vessel in nuclear power plants

    International Nuclear Information System (INIS)

    Romero C, J.; Fernandez T, F.; Perez R, N.; Rocamontes A, M.; Garcia R, R.

    2007-01-01

    The surveillance capsule is composed by the support, three capsules for impact test tubes, five capsules for tension test tubes and one porta dosemeters. The capsules for test tubes are of two types: rectangular capsule for Charpy test tubes and cylindrical capsule for tension test tubes. This work describes the development of the welding system to seal the capsules for test tubes that should contain helium of ultra high purity to a pressure of 1 atmosphere. (Author)

  16. Testing Placement of Gastric Feeding Tubes in Infants.

    Science.gov (United States)

    Metheny, Norma A; Pawluszka, Ann; Lulic, Melanie; Hinyard, Leslie J; Meert, Kathleen L

    2017-11-01

    Inadvertent positioning of a nasogastric tube in the lung can cause serious complications, so identifying methods to detect improperly inserted tubes is imperative. To compare the sensitivity, specificity, and negative and positive predictive values of 4 pH cut points (< 4.0, < 4.5, < 5.0, and < 5.5) in differentiating gastric and tracheal aspirates under various treatment conditions and to explore the utility of a pepsin assay for distinguishing between gastric and tracheal aspirates. Gastric and tracheal aspirates were collected from critically ill infants undergoing mechanical ventilation who had nasogastric or orogastric feeding tubes. Aspirates were tested with colorimetric pH indicators and a rapid pepsin assay. Information about treatment conditions was obtained from medical records. Two hundred twelve gastric aspirates and 60 tracheal aspirates were collected from 212 patients. Sensitivity was highest and specificity was lowest at the gastric aspirate pH cut point of less than 5.5. Positive predictive values were 100% at all pH cut points less than 5.0. Negative predictive values were higher at the pH cut point of less than 5.0 than at cut points less than 4.5. A higher percentage of pepsin-positive readings was found in gastric aspirates (88.3%) than in tracheal aspirates (5.4%). For a desired positive predictive value of 100%, a pH cut point of less than 5.0 provides the best negative predictive values, regardless of gastric acid inhibitor administration and feeding status. The pepsin assay is promising as an additional marker to distinguish gastric from tracheal aspirates. ©2017 American Association of Critical-Care Nurses.

  17. Design of experiments and equipment to test the ballooning characteristics of CANDU pressure tubes

    International Nuclear Information System (INIS)

    Forrest, C.F.; Stern, F.; Hart, R.G.

    1992-01-01

    Experiments have been planned and an apparatus has been designed to enable creep testing of end-of-life pressure tube specimens in a LOCA environment. Effects that could be studied include: annealing of irradiation damage during transient heating; effects of hydride blisters on pressure tube ballooning strains; and, effects of uniformly-distributed hydrogen content on pressure tube ballooning strains. The proposed experimental program will consist of separate effects creep tests on pressure tube sections under transient heating conditions

  18. Tuboimpedance: A New Test of Eustachian Tube Function.

    Science.gov (United States)

    Smith, Matthew E; Zou, Charlie C; Blythe, Andrew J C; Tysome, James R

    2017-04-01

    Objective Eustachian tube (ET) dysfunction is most frequently caused by a failure of the ET to adequately open; however, there is currently no reliable method of assessing this. Tubomanometry has recently shown good interindividual repeatability as a measure of ET function by measuring middle ear pressure after the application of regulated nasopharyngeal pressures during swallowing. We present the first reports of a novel test: middle ear impedance measurements during standard nasopharyngeal pressure application (tuboimpedance). We assess repeatability in healthy ears and any advantages over tubomanometry. Study Design Exploratory cohort diagnosis study. Setting Tertiary referral center. Subjects Twenty screened, healthy ears (10 volunteers). Methods Tubomanometry and tuboimpedance tests were performed while individuals swallowed with applied nasopharyngeal pressures of 20, 30, 40, and 50 mbar. Eustachian tube opening detection rate and test repeatability (measured by intraclass correlation coefficient [ICC]) for immediate and delayed repeats at each pressure were compared. Results ET opening was detected more frequently using tuboimpedance, with a 100% detection rate using a nasopharyngeal pressure of 30 mbar or more, compared to 88% to 96% with tubomanometry. Detection of ET opening at 20 mbar was possible with tuboimpedance. Repeatability of both tests was mostly strong (ICC >0.7) for both immediate and delayed repeats. Repeatability for the tubomanometry R value was only fair to moderate. Conclusion Tuboimpedance may provide a repeatable measure of ET opening that is easier to perform due to lower nasopharyngeal pressures required and fewer issues with poor ear-probe sealing. Further assessment in patients with different forms of ET dysfunction is required.

  19. Template synthesis of test tube nanoparticles using non-destructive replication.

    Science.gov (United States)

    Wagner, Jonathan; Yao, Jingyuan; Rodgers, David; Hinds, Bruce

    2013-03-01

    Nano test tubes are a promising delivery vehicle for a range of therapeutics, including small molecule drugs and biologics. However, current template synthesis methods of producing nano test tubes are prohibitively expensive and time consuming. Here, non-destructive template replication was used to increase nano test tube yield from porous alumina by more than a hundredfold. We demonstrate how to produce nano test tubes of several sizes and compositions, including hybrid tubes with different inner and outer surfaces for targeted surface chemistry. Nano test tubes were readily suspended and stored in aqueous solutions without the need for chemical treatment. These nano test tubes should find application as delivery vehicles for therapeutics, particularly for processive 'bionanoreactors' loaded with enzymes.

  20. Template synthesis of test tube nanoparticles using non-destructive replication

    International Nuclear Information System (INIS)

    Wagner, Jonathan; Rodgers, David; Yao Jingyuan; Hinds, Bruce

    2013-01-01

    Nano test tubes are a promising delivery vehicle for a range of therapeutics, including small molecule drugs and biologics. However, current template synthesis methods of producing nano test tubes are prohibitively expensive and time consuming. Here, non-destructive template replication was used to increase nano test tube yield from porous alumina by more than a hundredfold. We demonstrate how to produce nano test tubes of several sizes and compositions, including hybrid tubes with different inner and outer surfaces for targeted surface chemistry. Nano test tubes were readily suspended and stored in aqueous solutions without the need for chemical treatment. These nano test tubes should find application as delivery vehicles for therapeutics, particularly for processive ‘bionanoreactors’ loaded with enzymes. (paper)

  1. DNA nanotechnology from the test tube to the cell.

    Science.gov (United States)

    Chen, Yuan-Jyue; Groves, Benjamin; Muscat, Richard A; Seelig, Georg

    2015-09-01

    The programmability of Watson-Crick base pairing, combined with a decrease in the cost of synthesis, has made DNA a widely used material for the assembly of molecular structures and dynamic molecular devices. Working in cell-free settings, researchers in DNA nanotechnology have been able to scale up system complexity and quantitatively characterize reaction mechanisms to an extent that is infeasible for engineered gene circuits or other cell-based technologies. However, the most intriguing applications of DNA nanotechnology - applications that best take advantage of the small size, biocompatibility and programmability of DNA-based systems - lie at the interface with biology. Here, we review recent progress in the transition of DNA nanotechnology from the test tube to the cell. We highlight key successes in the development of DNA-based imaging probes, prototypes of smart therapeutics and drug delivery systems, and explore the future challenges and opportunities for cellular DNA nanotechnology.

  2. DNA nanotechnology from the test tube to the cell

    Science.gov (United States)

    Chen, Yuan-Jyue; Groves, Benjamin; Muscat, Richard A.; Seelig, Georg

    2015-09-01

    The programmability of Watson-Crick base pairing, combined with a decrease in the cost of synthesis, has made DNA a widely used material for the assembly of molecular structures and dynamic molecular devices. Working in cell-free settings, researchers in DNA nanotechnology have been able to scale up system complexity and quantitatively characterize reaction mechanisms to an extent that is infeasible for engineered gene circuits or other cell-based technologies. However, the most intriguing applications of DNA nanotechnology -- applications that best take advantage of the small size, biocompatibility and programmability of DNA-based systems -- lie at the interface with biology. Here, we review recent progress in the transition of DNA nanotechnology from the test tube to the cell. We highlight key successes in the development of DNA-based imaging probes, prototypes of smart therapeutics and drug delivery systems, and explore the future challenges and opportunities for cellular DNA nanotechnology.

  3. Assembly and method for testing the integrity of stuffing tubes

    Energy Technology Data Exchange (ETDEWEB)

    Morrison, E.F.

    1996-12-31

    A stuffing tube integrity checking assembly includes first and second annular seals, with each seal adapted to be positioned about a stuffing tube penetration component. An annular inflation bladder is provided, the bladder having a slot extending longitudinally there along and including a separator for sealing the slot. A first valve is in fluid communication with the bladder for introducing pressurized fluid to the space defined by the bladder when mounted about the tube. First and second releasible clamps are provided. Each clamp assembly is positioned about the bladder for securing the bladder to one of the seals for thereby establishing a fluid-tight chamber about the tube.

  4. Testing of Photomultiplier Tubes in a Magnetic Field

    Science.gov (United States)

    Waldron, Zachary; A1 Collaboration

    2016-09-01

    The A1 collaboration at MAMI in Mainz, Germany has designed a neutron detector that can be used in experiments to measure the electric form factor of the neutron. They will measure elastic scattering from the neutron, using the polarized electron beam from MAMI at A1's experimental hall. The detector will be composed of two walls of staggered scintillator bars which will be read out by photomultiplier tubes (PMT), connected to both ends of each scintillator via light guides. The experiment requires a magnetic field with strength of 1 Tesla, 2m away from the first scintillator wall. The resulting fringe field is sufficient to disrupt the PMTs, despite the addition of Mu Metal shielding. The effects of the fringe field on these PMTs was tested to optimize the amplification of the PMTs. A Helmholtz Coil was designed to generate a controlled magnetic field with equivalent strength to the field that the PMTs will encounter. The PMTs were read out using a multi-channel analyzer, were tested at various angles relative to the magnetic field in order to determine the optimal orientation to minimize signal disruption. Tests were also performed to determine: the neutron detector response to cosmic radiation; and the best method for measuring a magnetic field's strength in two dimensions. National Science Foundation Grant No. IIA-1358175.

  5. Preliminary research on eddy current bobbin quantitative test for heat exchange tube in nuclear power plant

    Science.gov (United States)

    Qi, Pan; Shao, Wenbin; Liao, Shusheng

    2016-02-01

    For quantitative defects detection research on heat transfer tube in nuclear power plants (NPP), two parts of work are carried out based on the crack as the main research objects. (1) Production optimization of calibration tube. Firstly, ASME, RSEM and homemade crack calibration tubes are applied to quantitatively analyze the defects depth on other designed crack test tubes, and then the judgment with quantitative results under crack calibration tube with more accuracy is given. Base on that, weight analysis of influence factors for crack depth quantitative test such as crack orientation, length, volume and so on can be undertaken, which will optimize manufacture technology of calibration tubes. (2) Quantitative optimization of crack depth. Neural network model with multi-calibration curve adopted to optimize natural crack test depth generated in in-service tubes shows preliminary ability to improve quantitative accuracy.

  6. Nondestructive testing of welds on thin-walled tubing

    Science.gov (United States)

    Hagemaier, D. J.; Posakony, G. J.

    1969-01-01

    Special ultrasonic search unit, or transducer assembly, reliably inspects the quality of melt-through welds of fusion welded tubing couplers for hydraulic lines. This instrumentation can also be used to detect faulty braze bonds in thin-walled, small diameter joints and wall thickness of thin-walled metal tubing.

  7. Using synthetic biology to make cells tomorrow's test tubes.

    Science.gov (United States)

    Garcia, Hernan G; Brewster, Robert C; Phillips, Rob

    2016-04-18

    The main tenet of physical biology is that biological phenomena can be subject to the same quantitative and predictive understanding that physics has afforded in the context of inanimate matter. However, the inherent complexity of many of these biological processes often leads to the derivation of complex theoretical descriptions containing a plethora of unknown parameters. Such complex descriptions pose a conceptual challenge to the establishment of a solid basis for predictive biology. In this article, we present various exciting examples of how synthetic biology can be used to simplify biological systems and distill these phenomena down to their essential features as a means to enable their theoretical description. Here, synthetic biology goes beyond previous efforts to engineer nature and becomes a tool to bend nature to understand it. We discuss various recent and classic experiments featuring applications of this synthetic approach to the elucidation of problems ranging from bacteriophage infection, to transcriptional regulation in bacteria and in developing embryos, to evolution. In all of these examples, synthetic biology provides the opportunity to turn cells into the equivalent of a test tube, where biological phenomena can be reconstituted and our theoretical understanding put to test with the same ease that these same phenomena can be studied in the in vitro setting.

  8. Shattered: Medawar's test tubes and their enduring legacy of chaos.

    Science.gov (United States)

    Bowles, J

    2000-02-01

    Medawar's 1952 paper 'An Unsolved Problem of Biology' underlies most subsequent theoretical work regarding the evolution of aging; it concludes that aging is accidental and could not have evolved; this prevents reconciling the growing body of evidence suggesting the existence of multiple, evolved, aging systems. The paper features a well-known thought experiment using test tubes to show why aging could not evolve. Medawar assumes that constant, random, breakage sufficiently represents lethal forces of nature; however, famine, drought, predation, disease, and accidents each uniquely affect populations. Predation is the only evolving force that continually invents new ways to kill members of the prey populations; thus all prey defenses to predation will eventually be defeated. Defenses to non-evolving or non-obligate lethal forces, however, should quickly evolve. Thus unevolving, identical test tubes cannot adequately represent biological populations. The example also ignores population booms and busts which often occur in nature. By ignoring these issues, Medawar examines only one population age distribution skewed towards younger individuals in predator-dominated environments while ignoring predator-free populations skewed towards older individuals after population crashes. Further, Medawar's test tubes lack meaningful competition for finite resources, and ignore declining fertility which occurs in all aging species. Medawar concludes that older individuals are too few in number to influence the population's gene pool for or against aging. This conclusion is found to be incorrect when variations in the age of reproductive senescence are introduced into a predator-free population.A new thought experiment with competing strains of algae corrects for these issues and shows that aging evolved and is retained so that groups retain enough genetic variability to allow for rapid evolution of a defense to novel predation. The example shows reasons why the rate of aging is

  9. Sensitivity of the improved Dutch tube diffusion test for detection of ...

    African Journals Online (AJOL)

    The sensitivity of the improved two-tube test for detection of antimicrobial residues in Kenyan milk was investigated by comparison with the commercial Delvo test SP. Suspect positive milk samples (n =244) from five milk collection centers, were analyzed with the improved two-tube and the commercial Delvo SP test as per ...

  10. Quality of Life Issues for Families Who Make the Decision to Use a Feeding Tube for Their Child with Disabilities.

    Science.gov (United States)

    Brotherson, Mary Jane; And Others

    1995-01-01

    Eight families deciding to use a feeding tube to meet the nutrition needs of their children with disabilities were interviewed over a two-year period. Family decision making in the context of quality of life was examined using a theoretical family systems model. Implications for future interventions are addressed. (Author/SW)

  11. New eddy current testing system in steam generator tubes

    International Nuclear Information System (INIS)

    Nagata, Yasuyuki; Shimone, Junri; Maeda, Kotaro; Harada, Yutaka; Murakami, Ryuji

    2003-01-01

    Eddy Current Testing (ECT) technique is applied to PWR Steam Generator (SG) tubes during refueling outage inspection. Bobbin type probe is generally used for the inspection, but it cannot provide sufficient detectability for very tight cracks. NEL, R/D Tech (Canada) and AECL (Canada) jointly developed new ECT probe. The probe is transmit and receive type array probe. It has axial defect detection mode and circumferential defect detection mode. Its inspection speed is as fast as conventional bobbin probe, and detectability performance is same or better than performance of rotating pancake coil (RPC) probe, which is used for detailed inspection. As a tester of the new probe, we have developed new ECT tester TC7700. It is able to transmit composite wave from the 4 independent oscillators (simultaneous excitation system) compared with the conventional inspection system. As regarding for field inspection system, we have integrated Zetec (USA) probe positioner, probe pusher and R/D Tech TC7700. We are also developing new analysis software. The software has automated data screening function, which can deal with large amount of data compared with conventional bobbin probe. We plan to perform a large-scale field trial using the probe and new system in near future. (author)

  12. Feasibility Test with a STS304 tube of the Eddy Current Test using a Bobbin Probe for the SMART SG Tube Inspection

    International Nuclear Information System (INIS)

    Lee, Yoon Sang; Jung, Hyun Kyu; Choung, Yun Hang

    2010-01-01

    The SMART SG tubes will be made of Alloy 690. The outside diameter will be 17 mm and the thickness will be 2.5 mm. They will be assembled helically around, and their innermost diameter will be about 600 mm and the total length will be about 32 meters. For the sake of safety, SMART SG tubes are designed for use with thick tubes such as 2.5 mm thickness compared to about 1 mm thickness of normal Korean standard pressurized water reactor tubes. Due to using thick tubes such as the 2.5 mm varieties, it was doubted that the Eddy Current Testing Method (ECT) would be a feasible method. Therefore we are trying to check the feasibility of the ECT using the substitute material STS304 tube instead of Alloy 690 tubes with the bobbin type ECT probe. The previous paper reported the feasibility of the ECT using modeling, but this paper will report the preliminary experimental results and comparison with the previous results of the modeling for the STS304 tube

  13. Using the noninformative families in family-based association tests : A powerful new testing strategy

    NARCIS (Netherlands)

    Lange, C; DeMeo, D; Silverman, EK; Weiss, ST; Laird, NM

    2003-01-01

    For genetic association studies with multiple phenotypes, we propose a new strategy for multiple testing with family-based association tests (FBATs). The strategy increases the power by both using all available family data and reducing the number of hypotheses tested while being robust against

  14. In-operation testing of condensers tubes in EDF thermal power plants

    International Nuclear Information System (INIS)

    Sermadiras, P.; Cormier, J.

    1982-01-01

    Electricite de France requires manufacturers to perform a number of tests on condenser tubes, as it does itself, including eddy current tests. This article describes the worksite inspection procedures, which use internal single-frequency probes to detect the following irregularities: - in differential mode: external corrosion, impacts, foreign matter, vibrations, internal behaviour of tubes; - in absolute mode: corrosion by ammonia [fr

  15. Numerical investigation of tube hyroforming of TWT using Corner Fill Test

    Science.gov (United States)

    Zribi, Temim; Khalfallah, Ali

    2018-05-01

    Tube hydroforming presents a very good alternative to conventional forming processes for obtaining good quality mechanical parts used in several industrial fields, such as the automotive and aerospace sectors. Research in the field of tube hydroforming is aimed at improving the formability, stiffness and weight reduction of manufactured parts using this process. In recent years, a new method of hydroforming appears; it consists of deforming parts made from welded tubes and having different thicknesses. This technique which contributes to the weight reduction of the hydroformed tubes is a good alternative to the conventional tube hydroforming. This technique makes it possible to build rigid and light structures with a reduced cost. However, it is possible to improve the weight reduction by using dissimilar tailor welded tubes (TWT). This paper is a first attempt to analyze by numerical simulation the behavior of TWT hydroformed in square cross section dies, commonly called (Corner Fill Test). Considered tubes are composed of two materials assembled by butt welding. The present analysis will focus on the effect of loading paths on the formability of the structure by determining the change in thickness in several sections of the part. A comparison between the results obtained by hydroforming the butt joint of tubes made of dissimilar materials and those obtained using single-material tube is achieved. Numerical calculations show that the bi-material welded tube has better thinning resistance and a more even thickness distribution in the circumferential directions when compared to the single-material tube.

  16. Garter spring location of pressure tube for PHWR using eddy current testing methods

    International Nuclear Information System (INIS)

    Lee, Y. S.; Yang, D. J.; Jeong, H. K.

    2001-01-01

    There are garter springs between pressure tube and calandria tube for PHWR. If the space of these garter springs become to be changed, the sagging of tube is caused and the contact between the pressure tube and calandria tube will cause the tube to be failed. AECL has applied the eddy current testing methods using send-receive type probe for this purpose, but this study apply eddy current testing methods using bobbin differential type probe to detection of garter spring location. And we did the computer simulation using VIC-3D code and compared it with experiments results for inspection 1 ∼ 11kHz. The results was that the garter spring signal was successfully detected for every frequency, and 5 kHz was best

  17. Sequence Design for a Test Tube of Interacting Nucleic Acid Strands.

    Science.gov (United States)

    Wolfe, Brian R; Pierce, Niles A

    2015-10-16

    We describe an algorithm for designing the equilibrium base-pairing properties of a test tube of interacting nucleic acid strands. A target test tube is specified as a set of desired "on-target" complexes, each with a target secondary structure and target concentration, and a set of undesired "off-target" complexes, each with vanishing target concentration. Sequence design is performed by optimizing the test tube ensemble defect, corresponding to the concentration of incorrectly paired nucleotides at equilibrium evaluated over the ensemble of the test tube. To reduce the computational cost of accepting or rejecting mutations to a random initial sequence, the structural ensemble of each on-target complex is hierarchically decomposed into a tree of conditional subensembles, yielding a forest of decomposition trees. Candidate sequences are evaluated efficiently at the leaf level of the decomposition forest by estimating the test tube ensemble defect from conditional physical properties calculated over the leaf subensembles. As optimized subsequences are merged toward the root level of the forest, any emergent defects are eliminated via ensemble redecomposition and sequence reoptimization. After successfully merging subsequences to the root level, the exact test tube ensemble defect is calculated for the first time, explicitly checking for the effect of the previously neglected off-target complexes. Any off-target complexes that form at appreciable concentration are hierarchically decomposed, added to the decomposition forest, and actively destabilized during subsequent forest reoptimization. For target test tubes representative of design challenges in the molecular programming and synthetic biology communities, our test tube design algorithm typically succeeds in achieving a normalized test tube ensemble defect ≤1% at a design cost within an order of magnitude of the cost of test tube analysis.

  18. Systems biological approach to investigate the lack of familial link between Down's Syndrome & Neural Tube Disorders.

    Science.gov (United States)

    Ragunath, Pk; Abhinand, Pa

    2013-01-01

    Systems Biology involves the study of the interactions of biological systems and ultimately their functions. Down's syndrome (DS) is one of the most common genetic disorders which are caused by complete, or occasionally partial, triplication of chromosome 21, characterized by cognitive and language dysfunction coupled with sensory and neuromotor deficits. Neural Tube Disorders (NTDs) are a group of congenital malformations of the central nervous system and neighboring structures related to defective neural tube closure during the first trimester of pregnancy usually occurring between days 18-29 of gestation. Several studies in the past have provided considerable evidence that abnormal folate and methyl metabolism are associated with onset of DS & NTDs. There is a possible common etiological pathway for both NTDs and Down's syndrome. But, various research studies over the years have indicated very little evidence for familial link between the two disorders. Our research aimed at the gene expression profiling of microarray datasets pertaining to the two disorders to identify genes whose expression levels are significantly altered in these conditions. The genes which were 1.5 fold unregulated and having a p-value disorders were recognized and over representation analysis was carried out for each of the constituent genes. The comprehensive manual analysis of these genes yields a hypothetical understanding of the lack of familial link between DS and NTDs. There were no genes involved with folic acid present in the dense cliques. Only - CBL, EGFR genes were commonly present, which makes the allelic variants of these genes - good candidates for future studies regarding the familial link between DS and NTDs. NTD - Neural Tube Disorders, DS - Down's Syndrome, MTHFR - Methylenetetrahydrofolate reductase, MTRR- 5 - methyltetrahydrofolate-homocysteine methyltransferase reductase.

  19. Automation of inspection methods for eddy current testing of steam generator tubes

    International Nuclear Information System (INIS)

    Meurgey, P.; Baumaire, A.

    1990-01-01

    Inspection of all the tubes of a steam generator when the reactor is stopped is required for some of these exchangers affected by stress corrosion cracking. Characterization of each crack, in each tube is made possible by the development of software for processing the signals from an eddy current probe. The ESTELLE software allows a rapid increase of tested tubes, more than 80,000 in 1989 [fr

  20. The efficacy of test tube warming devices used during oocyte retrieval for IVF.

    Science.gov (United States)

    Yeung, Queenie Sum Yee; Briton-Jones, Christine May; Tjer, Grace Ching Ching; Chiu, Tony Tak Yu; Haines, Christopher

    2004-10-01

    To investigate whether commonly used test tube warming devices maintain a constant temperature in follicular fluid aspirates. By using a digital thermocouple, temperature was measured and comparisons were made between an analog dry block heater, a digital dry block heater, and a thermostatic test tube heater. For small fluid volumes, temperature in the block heaters increased above 37 degrees C after being in the block for over 2 min. The thermostatic heater maintained a constant temperature, but this was below the factory setting of 36.9 degrees C. Temperature maintenance was influenced by fluid volume in each tube. One of the key factors in the handling of gametes and embryos is the maintenance of constant temperature. Test tube warming devices require verification of their ability to maintain fluid at the desired temperature. Temperature may vary with fluid volume and the type of test tube warming device used.

  1. Pressure tests to assess the significance of defects in boiler and superheater tubing

    International Nuclear Information System (INIS)

    Guest, J.C.; Hutchings, J.A.

    1975-01-01

    Internal pressure tests on 9 per cent Cr-1 per cent Mo steel tubing containing artificial defects demonstrated that the resultant loss of strength was less than a simple calculation based on the reduced tube thickness would suggest. Bursting tests on tubes containing longitudinal defects of varying length, depth and acuity showed notch strengthening at ambient temperature and at 550 0 C. A flow stress concept developed for simple bursting tests was shown to apply to creep conditions at 550 0 C. Results of creep and short-term bursting tests show that the length as well as the depth of the defect is an important factor affecting the life of bursting strength of the tubes. Defects less than 10 per cent of the tube thickness were found to have an insignificant effect. (author)

  2. Modeling and testing of a tube-in-tube separation mechanism of bodies in space

    Science.gov (United States)

    Michaels, Dan; Gany, Alon

    2016-12-01

    A tube-in-tube concept for separation of bodies in space was investigated theoretically and experimentally. The separation system is based on generation of high pressure gas by combustion of solid propellant and restricting the expansion of the gas only by ejecting the two bodies in opposite directions, in such a fashion that maximizes generated impulse. An interior ballistics model was developed in order to investigate the potential benefits of the separation system for a large range of space body masses and for different design parameters such as geometry and propellant. The model takes into account solid propellant combustion, heat losses, and gas phase chemical reactions. The model shows that for large bodies (above 100 kg) and typical separation velocities of 5 m/s, the proposed separation mechanism may be characterized by a specific impulse of 25,000 s, two order of magnitude larger than that of conventional solid rockets. It means that the proposed separation system requires only 1% of the propellant mass that would be needed for a conventional rocket for the same mission. Since many existing launch vehicles obtain such separation velocities by using conventional solid rocket motors (retro-rockets), the implementation of the new separation system design can reduce dramatically the mass of the separation system and increase safety. A dedicated experimental setup was built in order to demonstrate the concept and validate the model. The experimental results revealed specific impulse values of up to 27,000 s and showed good correspondence with the model.

  3. Fretting wear of steam generator tubes: high-temperature tests on AECL rig

    International Nuclear Information System (INIS)

    Guerout, F.; Zbinden, M.

    1993-07-01

    The R and DD has undertaken the study of fretting-wear of Alloy 600 S.G. tubes which occurs by contact with migrating items. The test series was performed in Canada at AECL Research (Atomic Energy of Canada Limited) as part of an exchange program. Four types of configuration were envisaged: a tube-to-drilled hole support contact which provides reference results and three types of tube-to-support contacts which simulate the tube fretting-wear induced by a welding rod, a threaded rod and a knife-edge rod support. This programme is completed by the study of the contact between a S.G. tube and a neighbouring S.G. tube which has been broken after plugging. (authors). 1 tab., 3 refs

  4. Sequence robust association test for familial data.

    Science.gov (United States)

    Dai, Wei; Yang, Ming; Wang, Chaolong; Cai, Tianxi

    2017-09-01

    Genome-wide association studies (GWAS) and next generation sequencing studies (NGSS) are often performed in family studies to improve power in identifying genetic variants that are associated with clinical phenotypes. Efficient analysis of genome-wide studies with familial data is challenging due to the difficulty in modeling shared but unmeasured genetic and/or environmental factors that cause dependencies among family members. Existing genetic association testing procedures for family studies largely rely on generalized estimating equations (GEE) or linear mixed-effects (LME) models. These procedures may fail to properly control for type I errors when the imposed model assumptions fail. In this article, we propose the Sequence Robust Association Test (SRAT), a fully rank-based, flexible approach that tests for association between a set of genetic variants and an outcome, while accounting for within-family correlation and adjusting for covariates. Comparing to existing methods, SRAT has the advantages of allowing for unknown correlation structures and weaker assumptions about the outcome distribution. We provide theoretical justifications for SRAT and show that SRAT includes the well-known Wilcoxon rank sum test as a special case. Extensive simulation studies suggest that SRAT provides better protection against type I error rate inflation, and could be much more powerful for settings with skewed outcome distribution than existing methods. For illustration, we also apply SRAT to the familial data from the Framingham Heart Study and Offspring Study to examine the association between an inflammatory marker and a few sets of genetic variants. © 2017, The International Biometric Society.

  5. Experimental Investigation of Reynolds Number Effects on Test Quality in a Hypersonic Expansion Tube

    Science.gov (United States)

    Rossmann, Tobias; Devin, Alyssa; Shi, Wen; Verhoog, Charles

    2017-11-01

    Reynolds number effects on test time and the temporal and spatial flow quality in a hypersonic expansion tube are explored using high-speed pressure, infrared optical, and Schlieren imaging measurements. Boundary layer models for shock tube flows are fairly well established to assist in the determination of test time and flow dimensions at typical high enthalpy test conditions. However, the application of these models needs to be more fully explored due to the unsteady expansion of turbulent boundary layers and contact regions separating dissimilar gasses present in expansion tube flows. Additionally, expansion tubes rely on the development of a steady jet with a large enough core-flow region at the exit of the acceleration tube to create a constant velocity region inside of the test section. High-speed measurements of pressure and Mach number at several locations within the expansion tube allow for the determination of an experimental x-t diagram. The comparison of the experimentally determined x-t diagram to theoretical highlights the Reynolds number dependent effects on expansion tube. Additionally, spatially resolved measurements of the Reynolds number dependent, steady core-flow in the expansion tube viewing section are shown. NSF MRI CBET #1531475, Lafayette College, McCutcheon Foundation.

  6. Tagging of Test Tubes with Electronic p-Chips for Use in Biorepositories.

    Science.gov (United States)

    Mandecki, Wlodek; Kopacka, Wesley M; Qian, Ziye; Ertwine, Von; Gedzberg, Katie; Gruda, Maryann; Reinhardt, David; Rodriguez, Efrain

    2017-08-01

    A system has been developed to electronically tag and track test tubes used in biorepositories. The system is based on a light-activated microtransponder, also known as a "p-Chip." One of the pressing problems with storing and retrieving biological samples at low temperatures is the difficulty of reliably reading the identification (ID) number that links each storage tube with the database containing sample details. Commonly used barcodes are not always reliable at low temperatures because of poor adhesion of the label to the test tube and problems with reading under conditions of frost and ice accumulation. Traditional radio frequency identification (RFID) tags are not cost effective and are too large for this application. The system described herein consists of the p-Chip, p-Chip-tagged test tubes, two ID readers (for single tubes or for racks of tubes), and software. We also describe a robot that is configured for retrofitting legacy test tubes in biorepositories with p-Chips while maintaining the temperature of the sample below -50°C at all times. The main benefits of the p-Chip over other RFID devices are its small size (600 × 600 × 100 μm) that allows even very small tubes or vials to be tagged, low cost due to the chip's unitary construction, durability, and the ability to read the ID through frost and ice.

  7. Maize EMBRYO SAC family peptides interact differentially with pollen tubes and fungal cells.

    Science.gov (United States)

    Woriedh, Mayada; Merkl, Rainer; Dresselhaus, Thomas

    2015-08-01

    EMBRYO SAC1-4 (ES1-4) peptides belong to the defensin subgroup of cysteine-rich peptides known to mediate pollen tube burst in Zea mays (maize). ES1-4 are reported here to also be capable of inhibiting germination and growth of the maize fungal pathogens Fusarium graminearum and Ustilago maydis at higher concentrations. Dividing the peptides into smaller pieces showed that a 15-amino-acid peptide located in a highly variable loop region lacking similarity to other defensins or defensin-like peptides binds to maize pollen tube surfaces, causing swelling prior to burst. This peptide fragment and a second conserved neighbouring fragment showed suppression of fungal germination and growth. The two peptides caused swelling of fungal cells, production of reactive oxygen species, and finally the formation of big vacuoles prior to burst at high peptide concentration. Furthermore, peptide fragments were found to bind differently to fungal cells. In necrotrophic F. graminearum, a peptide fragment named ES-d bound only at cell surfaces whereas the peptide ES-c bound at cell surfaces and also accumulated inside cells. Conversely, in biotrophic U. maydis, both peptide fragments accumulated inside cells, but, if applied at higher concentration, ES-c but not ES-d accumulated mainly in vacuoles. Mapping of peptide interaction sites identified amino acids differing in pollen tube burst and fungal response reactions. In summary, these findings indicate that residues targeting pollen tube burst in maize are specific to the ES family, while residues targeting fungal growth are conserved within defensins and defensin-like peptides. © The Author 2015. Published by Oxford University Press on behalf of the Society for Experimental Biology.

  8. Development of ultrasonic testing scanner for NPP steam generator tubes (I)

    International Nuclear Information System (INIS)

    Shin, J. I.; Huh, H.

    1998-12-01

    Testing tubes are designed and fabricated to investigate the optimum test conditions through the various experiments. The proto-type P/C-controlled automatic rotating scanner is fabricated to obtain the ultrasonic data automatically from test tubes. It was attempted to visualize the shape of defects presented inside the specimen using peak amplitude at each point. However, further research works will be needed to be applied at the plant site as a more reliable technology

  9. Cryogenic testing of fluoropolymer-coated stainless steel tubing

    International Nuclear Information System (INIS)

    Dooley, J.B.

    1989-11-01

    Stainless steel tubing coated internally with two different types of fluorinated polymers were subjected to microscopic examination after a welding operation had been performed on the tubing. The welded assemblies were photographed and subjected to repeated cycles between liquid helium and room temperature. The green tetrafluoroethylene (TFE) coating peeled back in the area subjected to welding heat and displayed cracking all over its surface without regard to proximity to the weld area. The dark fluorinated ethylene propylene (FEP) coating showed a tendency to char or burn away progressively in the weld area. The dark (FEP) coating did not crack as extensively as the green TFE coating, but did show a few areas of ''crazing'' or cracking of the topmost surface after cryogenic exposure. 12 figs

  10. Fabrication and mechanical testing of fibre reinforced thermoplastic composite tubes

    International Nuclear Information System (INIS)

    Tufail, M.

    2005-01-01

    Polymer based composites are produced using less expensive moulds and quick fabrication techniques. The overall processing cost for such materials is much lesser than metallic materials. Usually monolithic parts are produced out of composite materials which further decreases the processing time needed for joining sub- , assemblies as in the case of metallic parts. Any defects encountered due to sub-assemblies are also eliminated. Thermoset based composites have been used for long time to produce parts for automotive, aerospace, marine, and sports industries. The properties thus obtained by using thermoset as matrix are very well in comparison with metals but certain draw backs a.e there with this kind of matrix. Thermoset based composites are processed in untidy environment and once the object is produced can not be reshaped. In contrary to that thermoplastic materials are processed in a clean environment and the material can be recycled. The component once produced can easily be reshaped if required as no chemical reaction does take place during the process. Although the high melt viscosity of thermoplastic has limited its application as due to its high viscosity, its processing would be very difficult. Various methods have been developed to resolve this issue. In this study, a commingled material has been used to produce thermoplastic based composite tubes. The method developed for making such tubes is defined along with the method adopted to measure some of the mechanical properties of these tubes. (author)

  11. Preliminary studies of microchannel plate photomultiplier tube neutron detectors for flight test applications

    International Nuclear Information System (INIS)

    Dolan, K.W.

    1978-10-01

    Electrical, mechanical, thermal, and neutron response data indicate that microchannel plate photomultiplier tubes are viable candidates as miniature, ruggedized neutron detectors for flight test applications in future weapon systems

  12. Test bench HEATREC for heat loss measurement on solar receiver tubes

    Science.gov (United States)

    Márquez, José M.; López-Martín, Rafael; Valenzuela, Loreto; Zarza, Eduardo

    2016-05-01

    In Solar Thermal Electricity (STE) plants the thermal energy of solar radiation is absorbed by solar receiver tubes (HCEs) and it is transferred to a heat transfer fluid. Therefore, heat losses of receiver tubes have a direct influence on STE plants efficiency. A new test bench called HEATREC has been developed by Plataforma Solar de Almería (PSA) in order to determinate the heat losses of receiver tubes under laboratory conditions. The innovation of this test bench consists in the possibility to determine heat losses under controlled vacuum.

  13. Elastic Stability of Concentric Tube Robots: A Stability Measure and Design Test.

    Science.gov (United States)

    Gilbert, Hunter B; Hendrick, Richard J; Webster, Robert J

    2016-02-01

    Concentric tube robots are needle-sized manipulators which have been investigated for use in minimally invasive surgeries. It was noted early in the development of these devices that elastic energy storage can lead to rapid snapping motion for designs with moderate to high tube curvatures. Substantial progress has recently been made in the concentric tube robot community in designing snap-free robots, planning stable paths, and characterizing conditions that result in snapping for specific classes of concentric tube robots. However, a general measure for how stable a given robot configuration is has yet to be proposed. In this paper, we use bifurcation and elastic stability theory to provide such a measure, as well as to produce a test for determining whether a given design is snap-free (i.e. whether snapping can occur anywhere in the unloaded robot's workspace). These results are useful in designing, planning motions for, and controlling concentric tube robots with high curvatures.

  14. Out-of pile mechanical test: simulating reactivity initiated accident (RIA) of zircaloy-4 cladding tube

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Myung Ho; Kim, Jun Hwan; Choi, Byoung Kwon; Jeong, Young Hwan [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of)

    2004-07-01

    The ejection or drop of a control rod in a reactivity initiated accident (RIA) causes a sudden increase in reactor power and in turn deposits a large amount of energy into the fuel. In a RIA, cladding tubes bear thermal expansion due to sudden reactivity and may fail from the resulting mechanical damage. Thus, RIA can be one of the safety margin reducers because the oxide on the tubes makes their thickness to support the load less as well as hydrides from the corrosion reduce the ductility of the tubes. In a RIA, the peak of reactor power from reactivity change is about 0.1m second and the temperature of the cladding tubes increases up to 1000 .deg. C in several seconds. Although it is hard to fully simulate the situation, several attempts to measure the change of mechanical properties under a RIA situation has done using a reduction coil, ring tension tests with high speed. This research was done to see the effect of oxide on the change of circumferential strength and ductility of Zircaloy-4 tubes in a RIA. The ring stretch tensile tests were performed with the strain rate of 1/sec and 0.01/s to simulate a transient of the cladding tube under a RIA. Since the test results of the ring tensile test are very sensitive to the lubricant, the tests were also carried out to select a suitable lubricant before the test of oxided specimens.

  15. Autobiologies on YouTube: Narratives of Direct-to-Consumer Genetic Testing

    Science.gov (United States)

    Harris, Anna; Kelly, Susan E.; Wyatt, Sally

    2014-01-01

    Despite a growing personal genomics market, little is known about how people engage with the possibilities offered by direct-to-consumer (DTC) genetic testing. In order to help address this gap, this study deploys narrative analysis of YouTube videos posted by individuals who have purchased DTC genetic testing for disease. Genetic testing is said to be contributing to new states of illness, where individuals may become “patients-in-waiting.” In the videos analyzed, we found a new form of storytelling about this ambiguous state of illness, which we refer to as autobiology. Autobiology – the study of, and story about, one's own biology – concerns narratives of sense-making through forms of biological practice, as well as wayfaring narratives which interweave genetic markers and family histories of disease. These autobiologies – part of a broader shift toward public stories about genetics and other healthcare technologies – exhibit playfulness, as well as being bound with consumerist practices. PMID:24772003

  16. Fireside corrosion testing of candidate superheater tube alloys, coatings, and claddings -- Phase 2 field testing

    Energy Technology Data Exchange (ETDEWEB)

    Blough, J.L. [Foster Wheeler Development Corp., Livingston, NJ (United States)

    1996-08-01

    In Phase 1 of this project, a variety of developmental and commercial tubing alloys and claddings was exposed to laboratory fireside corrosion testing simulating a superheater or reheater in a coal-fired boiler. Phase 2 (in situ testing) has exposed samples of 347, RA85H, HR3C, 253MA, Fe{sub 3}Al + 5Cr, 310 modified, NF 709, 690 clad, and 671 clad for over 10,000 hours to the actual operating conditions of a 250-MW coal-fired boiler. The samples were installed on air-cooled, retractable corrosion probes, installed in the reheater cavity, controlled to the operating metal temperatures of an existing and advanced-cycle, coal-fired boiler. Samples of each alloy are being exposed for 4,000, 12,000, and 16,000 hours of operation. The present results are for the metallurgical examination of the corrosion probe samples after approximately 4,400 hours of exposure.

  17. Testing of a 7-tube palladium membrane reactor for potential use in TEP

    International Nuclear Information System (INIS)

    Carlson, Bryan J.; Trujillo, Stephen; Willms, R. Scott

    2010-01-01

    A Palladium Membrane Reactor (PMR) consists of a palladium/silver membrane permeator filled with catalyst (catalyst may be inside or outside the membrane tubes). The PMR is designed to recover tritium from the methane, water, and other impurities present in fusion reactor effluent. A key feature of a PMR is that the total hydrogen isotope content of a stream is significantly reduced as (1) methane-steam reforming and/or water-gas shift reactions proceed on the catalyst bed and (2) hydrogen isotopes are removed via permeation through the membrane. With a PMR design matched to processing requirements, nearly complete hydrogen isotope removals can be achieved. A 3-tube PMR study was recently completed. From the results presented in this study, it was possible to conclude that a PMR is appropriate for TEP, perforated metal tube protectors function well, platinum on aluminum (PtA) catalyst performs the best, conditioning with air is probably required to properly condition the Pd/Ag tubes, and that CO/CO 2 ratios maybe an indicator of coking. The 3-tube PMR had a permeator membrane area of 0.0247 m 2 and a catalyst volume to membrane area ratio of 4.63 cc/cm 2 (with the catalyst on the outside of the membrane tubes and the catalyst only covering the membrane tube length). A PMR for TEP will require a larger membrane area (perhaps 0.35 m 2 ). With this in mind, an intermediate sized PMR was constructed. This PMR has 7 permeator tubes and a total membrane area of 0.0851 m 2 . The catalyst volume to membrane area ratio for the 7-tube PMR was 5.18 cc/cm 2 . The total membrane area of the 7-tube PMR (0.0851 m 2 ) is 3.45 times larger than total membrane area of the 3-tube PMR (0.0247 m 2 ). The following objectives were identified for the 7-tube PMR tests: (1) Refine test measurements, especially humidity and flow; (2) Refine maintenance procedures for Pd/Ag tube conditioning; (3) Evaluate baseline PMR operating conditions; (4) Determine PMR scaling method; (5) Evaluate PMR

  18. Experimental investigation of thermal-hydraulic performance of PCCS with horizontal tube heat exchangers: single U-tube test

    International Nuclear Information System (INIS)

    Nakamura, Hideo; Anoda, Yoshinari; Arai, Kenji; Kurita, Tomohisa

    2000-01-01

    JAERI and JAPC started a cooperative study to verify performance of a PCCS (Passive Containment Cooling System) using horizontal heat exchanger for next-generation BWR in 1998. A test facility with a horizontal single U-tube was constructed in JAERI in 1999 to investigate fundamental condensation behavior under influences of non-condensable gas. Preliminary pre-test analyses were performed using RELAP5/ MOD3.2.1.2 code to expect the experimental outcomes by incorporating a correlation for condensation degradation because of non-condensable gas by Ueno et al. for better prediction. Preliminary results from both experiments (shakedown) and pre-test analyses indicated that the PCCS using horizontal U-tube heat exchanger is promising. Steam generated under assumed severe accident conditions; steam generation rate approx. = 1% core power, non-condensable gas concentration of 1% and simulated containment vessel pressure of 0.7 MPa, was totally condensed with a small differential pressure across inlet and outlet plenum. Experimental data will be accumulated to develop models and correlations for a better prediction of responses of the PCCS using horizontal heat exchanger during postulated severe accidents. (author)

  19. Status of the bench-test system for the tubes in the HIMAC DTL linac

    International Nuclear Information System (INIS)

    Fujimoto, T.; Ishikawa, S.; Kobayashi, C.

    2000-01-01

    The tetrode tube of SIEMENS RS2074SK is used for HIMAC DTL (Drift Tube Linac) 1.4 MW final amplifiers. We installed a bench-test system for this tube in 1999. This system can be used under low power operation with CW mainly for filament aging. This system consists of DC sources, drive-amplifier (5 kW transistor amplifier) and 3/4λ coaxial input and output circuits. We will also use this system to improve the DTL final amplifiers, for example to reduce the parasitic oscillation level. This paper describes status of this system. (author)

  20. Test plan for Fauske and Associates to perform tube propagation experiments with simulated Hanford tank wastes

    International Nuclear Information System (INIS)

    Carlson, C.D.; Babad, H.

    1996-05-01

    This test plan, prepared at Pacific Northwest National Laboratory for Westinghouse Hanford Company, provides guidance for performing tube propagation experiments on simulated Hanford tank wastes and on actual tank waste samples. Simulant compositions are defined and an experimental logic tree is provided for Fauske and Associates (FAI) to perform the experiments. From this guidance, methods and equipment for small-scale tube propagation experiments to be performed at the Hanford Site on actual tank samples will be developed. Propagation behavior of wastes will directly support the safety analysis (SARR) for the organic tanks. Tube propagation may be the definitive tool for determining the relative reactivity of the wastes contained in the Hanford tanks. FAI have performed tube propagation studies previously on simple two- and three-component surrogate mixtures. The simulant defined in this test plan more closely represents actual tank composition. Data will be used to support preparation of criteria for determining the relative safety of the organic bearing wastes

  1. The EL-4 reactor. Changing of a pressure tube on a test loop

    International Nuclear Information System (INIS)

    Foulquier, H.; Clara, P.

    1964-01-01

    Right from the beginning of the EL-4 project, the research convected with the overall design of the reactor was guided by the various technical specifications resulting from a justifiable concern about the reliability. The external and internal tubes of each layer situated in the reactor block had in particular to be interchangeable. The research alone into the dismantling of the external tube, i.e in fact the pressure tube, justified a certain number of full-scale tests on a model. The tests carried out under relevant conditions on a non-irradiated structure made it possible to define a complete ranger of of positioning and un-positioning sequences at a distance for such a pressure tube. (authors) [fr

  2. Controlatron Neutron Tube Test Suite Software Manual - Operation Manual (V2.2)

    CERN Document Server

    Noel, W P; Hertrich, R J; Martinez, M L; Wallace, D L

    2002-01-01

    The Controlatron Software Suite is a custom built application to perform automated testing of Controlatron neutron tubes. The software package was designed to allowing users to design tests and to run a series of test suites on a tube. The data is output to ASCII files of a pre-defined format for data analysis and viewing with the Controlatron Data Viewer Application. This manual discusses the operation of the Controlatron Test Suite Software and a brief discussion of state machine theory, as state machine is the functional basis of the software.

  3. Studies of the steam generator degraded tubes behavior on BRUTUS test loop

    Energy Technology Data Exchange (ETDEWEB)

    Chedeau, C.; Rassineux, B. [EDF/DER/MTC, Moret Sur Loing (France); Flesch, B. [EDF/EPN/DMAINT, Paris (France)] [and others

    1997-04-01

    Studies for the evaluation of steam generator tube bundle cracks in PWR power plants are described. Global tests of crack leak rates and numerical calculations of crack opening area are discussed in some detail. A brief overview of thermohydraulic studies and the development of a mechanical probabilistic design code is also given. The COMPROMIS computer code was used in the studies to quantify the influence of in-service inspections and maintenance work on the risk of a steam generator tube rupture.

  4. Round robin tests of the PISC III programme on defective steam generators tubes

    International Nuclear Information System (INIS)

    Birac, C.; Herkenrath, H.; Crutzen, S.; Miyake, Y.; Maciga, G.

    1991-11-01

    The PISC III actions are intended to extend the results and methodologies of the previous PISC exercises, i.e. the assessment of the capabilities of the various examination techniques when used on real or realistic flaws in real components under real conditions of inspection. Being aware of the industrial problems that the degradation of steam generator tubes can create, the PISC III management board decided to include in the PISC III programme a special action on steam generator tubes testing (SGT). (author)

  5. NASA Lewis Stirling SPRE testing and analysis with reduced number of cooler tubes

    International Nuclear Information System (INIS)

    Wong, W.A.; Cairelli, J.E.; Swec, D.M.; Doeberling, T.J.; Lakatos, T.F.; Madi, F.J.

    1994-01-01

    Free-piston Stirling power converters are a candidate for high capacity space power applications. The Space Power Research Engine (SPRE), a free-piston Stirling engine coupled with a linear alternator, is being tested at the NASA Lewis Research Center in support of the Civil Space Technology Initiative. The SPRE is used as a test bed for evaluating converter modifications which have the potential to improve converter performance and for validating computer code predictions. Reducing the number of cooler tubes on the SPRE has been identified as a modification with the potential to significantly improve power and efficiency. This paper describes experimental tests designed to investigate the effects of reducing the number of cooler tubes on converter power, efficiency and dynamics. Presented are test results from the converter operating with a reduced number of cooler tubes and comparisons between this data and both baseline test data and computer code predictions

  6. Fluid elastic instability tests on an array of tubes preferentially flexible in the flow direction

    International Nuclear Information System (INIS)

    Mureithi, N.W.; Zhang, C.; Pettigrew, M.J.

    2004-01-01

    The present work is motivated by the observation that, in the presence of flat bar supports (AVBs), U-tubes in steam generators and heat exchangers are not positively restrained in the in-plane direction. The stability behavior of a rotated triangular array is investigated in detail in the work presented here. Tubes within the array are flexible only in the flow direction. Tests are conducted with a fully flexible array, a single flexible tube, and a finite number of flexible tubes at several locations within the otherwise rigid array. In all cases tube flexibility is purely in the flow direction. The fully flexible array is shown to undergo fluid-elastic instability. Despite the unidirectional flexibility constraint, the critical instability velocity is of the same order of magnitude when compared with previous tests on an unconstrained fully flexible array. A single flexible tube, on the other hand, is found to be stable. Results of tests on partially flexible array configurations are also presented. (authors)

  7. Risks of Using Bedside Tests to Verify Nasogastric Tube Position in Adult Patients

    Directory of Open Access Journals (Sweden)

    Melody Ni

    2014-12-01

    Full Text Available Nasogastric (NG tubes are commonly used for enteral feeding. Complications of feeding tube misplacement include malnutrition, pulmonary aspiration, and even death. We built a Bayesian network (BN to analyse the risks associated with available bedside tests to verify tube position. Evidence on test validity (sensitivity and specificity was retrieved from a systematic review. Likelihood ratios were used to select the best tests for detecting tubes misplaced in the lung or oesophagus. Five bedside tests were analysed including magnetic guidance, aspirate pH, auscultation, aspirate appearance, and capnography/colourimetry. Among these, auscultation and appearance are non-diagnostic towards lung or oesophagus placements. Capnography/ colourimetry can confirm but cannot rule out lung placement. Magnetic guidance can rule out both lung and oesophageal placement. However, as a relatively new technology, further validation studies are needed. The pH test with a cut-off at 5.5 or lower can rule out lung intubation. Lowering the cut-off to 4 not only minimises oesophageal intubation but also provides extra safety as the sensitivity of pH measurement is reduced by feeding, antacid medication, or the use of less accurate pH paper. BN is an effective tool for representing and analysing multi-layered uncertainties in test validity and reliability for the verification of NG tube position. Aspirate pH with a cut-off of 4 is the safest bedside method to minimise lung and oesophageal misplacement.

  8. Optimum Frequency for Eddy Current Testing Method of SMART SG tubes

    International Nuclear Information System (INIS)

    Lee, Yoon Sang; Jung, Hyun Kyu; Choung, Yun Hang

    2009-01-01

    The SMART SG tubes will be made of Alloy 690. The outside diameter will be 17 mm and the thickness will be 2.5 mm. They will be assembled helically around, and their innermost diameter will be about 600 mm and the total length will be about 32 meters. For safety, SMART SG tubes are designed for use with thick tubes such as 2.5 mm thickness compared to about 1 mm thickness of normal Korean standard pressurized water reactor tubes. Due to using thick tubes such as 2.5 mm varieties, it was doubted that the Eddy Current Testing Method (ECT) would be a feasible method. Therefore we are trying to simulate the bobbin probe signal for SMART SG tubes and comparing it to PWR SG ECT probe signal using VIM software, checking for the applicability of ECT. Also we are trying to compare the ECT signal of 2.5 mm thick stainless tubes to check if they are possible substitute material

  9. The sky blue method as a screening test to detect misplacement of percutaneous endoscopic gastrostomy tube at exchange.

    Science.gov (United States)

    Suzuki, Yutaka; Urashima, Mitsuyoshi; Yoshida, Hideki; Iwase, Tsuyoshi; Kura, Toshiroh; Imazato, Shin; Kudo, Michiaki; Ohta, Tomoyuki; Mizuhara, Akihiro; Tamamori, Yutaka; Muramatsu, Hirohito; Nishiguchi, Yukio; Nishiyama, Yorihiro; Takahashi, Mikako; Nishiwaki, Shinji; Matsumoto, Masami; Goshi, Satoshi; Sakamoto, Shigeo; Uchida, Nobuyuki; Ijima, Masashi; Ogawa, Tetsushi; Shimazaki, Makoto; Takei, Shinichi; Kimura, Chikou; Yamashita, Satoyoshi; Endo, Takao; Nakahori, Masato; Itoh, Akihiko; Kusakabe, Toshiro; Ishizuka, Izumi; Iiri, Takao; Fukasawa, Shingo; Arimoto, Yukitsugu; Kajitani, Nobuaki; Ishida, Kazuhiko; Onishi, Koji; Taira, Akihiko; Kobayashi, Makoto; Itano, Yasuto; Kobuke, Toshiya

    2009-01-01

    During tube exchange for percutaneous endoscopic gastrostomy (PEG), a misplaced tube can cause peritonitis and death. Thus, endoscopic or radiologic observation is required at tube exchange to make sure the tube is placed correctly. However, these procedures cost extensive time and money to perform in all patients at the time of tube exchange. Therefore, we developed the "sky blue method" as a screening test to detect misplacement of the PEG tube during tube exchange. First, sky blue solution consisting of indigocarmine diluted with saline was injected into the gastric space via the old PEG tube just before the tube exchange. Next, the tube was exchanged using a standard method. Then, we checked whether the sky blue solution could be collected through the new tube or not. Finally, we confirmed correct placement of the tube by endoscopic or radiologic observation for all patients. A total of 961 patients were enrolled. Each tube exchange took 1 to 3 minutes, and there were no adverse effects. Four patients experienced a misplaced tube, all of which were detectable with the sky blue method. Diagnostic parameters of the sky blue method were as follows: sensitivity, 94% (95%CI: 92-95%); specificity, 100% (95%CI: 40-100%); positive predictive value, 100% (95%CI: 100-100%); negative predictive value, 6% (95%CI: 2-16%). These results suggest that the number of endoscopic or radiologic observations to confirm correct replacement of the PEG tube may be reduced to one fifteenth using the sky blue method.

  10. Using a Bedside Video-assisted Test Tube Test to Assess Stoma Viability: A Report of 4 Cases.

    Science.gov (United States)

    Ahmad, Sarwat; Turner, Keli; Shah, Paulesh; Diaz, Jose

    2016-07-01

    Mucosal discoloration of an intestinal stoma may indicate self-limited venous congestion or necrosis necessitating operative revision. A common bedside technique to assess stoma viability is the "test tube test". A clear tube is inserted into the stoma and a hand-held light is used to assess the color of the stoma. A technique (video-assisted test tube test [VATTT]) developed by the authors utilizes a standard video bronchoscope inserted into a clear plastic blood collection tube to visually inspect and assess the mucosa. This technique was evaluated in 4 patients (age range 49-72 years, all critically ill) with a discolored stoma after emergency surgery. In each case, physical exam revealed ischemic mucosa at the surface either immediately after surgery or after worsening hypotension weeks later. Serial test tube test assessments were ambiguous when trying to assess deeper mucosa. The VATTT assessment showed viable pink mucosa beneath the surface and until the fascia was revealed in 3 patients. One (1) patient had mucosal ischemia down to the fascia, which prompted operative revision of the stoma. The new stoma was assessed with a VATTT and was viable for the entire length of the stoma. VATTT provided an enhanced, magnified, and clearer way to visually assess stoma viability in the postoperative period that can be performed at the bedside with no adverse events. It may prevent unnecessary relaparotomy or enable earlier diagnosis of deep ostomy necrosis. Validity and reliability studies are warranted.

  11. Scramjet test flow reconstruction for a large-scale expansion tube, Part 2: axisymmetric CFD analysis

    Science.gov (United States)

    Gildfind, D. E.; Jacobs, P. A.; Morgan, R. G.; Chan, W. Y. K.; Gollan, R. J.

    2017-11-01

    This paper presents the second part of a study aiming to accurately characterise a Mach 10 scramjet test flow generated using a large free-piston-driven expansion tube. Part 1 described the experimental set-up, the quasi-one-dimensional simulation of the full facility, and the hybrid analysis technique used to compute the nozzle exit test flow properties. The second stage of the hybrid analysis applies the computed 1-D shock tube flow history as an inflow to a high-fidelity two-dimensional-axisymmetric analysis of the acceleration tube. The acceleration tube exit flow history is then applied as an inflow to a further refined axisymmetric nozzle model, providing the final nozzle exit test flow properties and thereby completing the analysis. This paper presents the results of the axisymmetric analyses. These simulations are shown to closely reproduce experimentally measured shock speeds and acceleration tube static pressure histories, as well as nozzle centreline static and impact pressure histories. The hybrid scheme less successfully predicts the diameter of the core test flow; however, this property is readily measured through experimental pitot surveys. In combination, the full test flow history can be accurately determined.

  12. Effect of tubing condensate on non-invasive positive pressure ventilators tested under simulated clinical conditions.

    Science.gov (United States)

    Hart, Diana Elizabeth; Forman, Mark; Veale, Andrew G

    2011-09-01

    Water condensate in the humidifier tubing can affect bi-level ventilation by narrowing tube diameter and increasing airflow resistance. We investigated room temperature and tubing type as ways to reduce condensate and its effect on bi-level triggering and pressure delivery. In this bench study, the aim was to test the hypothesis that a relationship exists between room temperature and tubing condensate. Using a patient simulator, a Res-med bi-level device was set to 18/8 cm H(2)O and run for 6 h at room temperatures of 16°C, 18°C and 20°C. The built-in humidifier was set to a low, medium or high setting while using unheated or insulated tubing or replaced with a humidifier using heated tubing. Humidifier output, condensate, mask pressure and triggering delay of the bi-level were measured at 1 and 6 h using an infrared hygrometer, metric weights, Honeywell pressure transducer and TSI pneumotach. When humidity output exceeded 17.5 mg H(2)O/L, inspiratory pressure fell by 2-15 cm H(2)O and triggering was delayed by 0.2-0.9 s. Heating the tubing avoided any such ventilatory effect whereas warmer room temperatures or insulating the tubing were of marginal benefit. Users of bi-level ventilators need to be aware of this problem and its solution. Bi-level humidifier tubing may need to be heated to ensure correct humidification, pressure delivery and triggering.

  13. Assessment of thin-walled cladding tube mechanical properties by segmented expanding Mandrel test

    International Nuclear Information System (INIS)

    Nilsson, Karl-Fredrik

    2015-01-01

    This paper presents the principles of the segmented expanding mandrel test for thin-walled cladding tubes, which can be used as a basic material characterisation test to determine stress-strain curves and ductility or as a test to simulate mechanical pellet-cladding interaction. The paper discusses the strengths and weaknesses of the test method and it illustrates how the test can be used to simulate hydride reorientations in zirconium claddings and quantify how hydride reorientation affects ductility. (authors)

  14. Design and test of the Stirling-type pulse tube cryocooler

    Science.gov (United States)

    Hong, Yong-Ju; Ko, Junseok; Kim, Hyo-Bong; Yeom, Han-Kil; In, Sehwan; Park, Seong-Je

    2017-12-01

    Stirling type pulse tube cryocoolers are very attractive for cooling of diverse application because it has it has several inherent advantages such as no moving part in the cold end, low manufacturing cost and long operation life. To develop the Stirling-type pulse tube cryocooler, we need to design a linear compressor to drive the pulse tube cryocooler. A moving magnet type linear motor of dual piston configuration is designed and fabricated, and this compressor could be operated with the electric power of 100 W and the frequency up to 60 Hz. A single stage coaxial type pulse tube cold finger aiming at over 1.5 W at 80K is built and tested with the linear compressor. Experimental investigations have been conducted to evaluate their performance characteristics with respect to several parameters such as the phase shifter, the charging pressure and the operating frequency of the linear compressor.

  15. History of the water chemistry for the few tube test model

    International Nuclear Information System (INIS)

    Moss, S.A.; Simpson, J.L.

    1979-09-01

    The water chemistry activities carried out in support of the Few Tube Test are described. This test was conducted to provide design confirmation data for the Clinch River Breeder Reactor Project (CRBRP) steam generators. Proposed CRBRP chemistry was followed; all volatile treatment (AVT) of water was carried out with on-line monitoring capability

  16. Can serums be replaced by Mueller‑Hinton agar in germ tube test ...

    African Journals Online (AJOL)

    Background: The germ tube test (GTT) is inexpensive, easy, and well‑defined test that differentiates Candida albicans (excluding Candida dubliniensis and Candida africana) from other species. The aim of this study was to evaluate various serums (i.e., human, rabbit, horse, and fetal bovine serum) used in the GTT and ...

  17. Bulge testing of copper and niobium tubes for hydroformed RF cavities

    Energy Technology Data Exchange (ETDEWEB)

    Kim, H.S., E-mail: kim.3237@osu.edu [Department of Materials Science and Engineering, The Ohio State University, Columbus, OH (United States); Sumption, M.D. [Department of Materials Science and Engineering, The Ohio State University, Columbus, OH (United States); Susner, M.A. [Department of Materials Science and Engineering, The Ohio State University, Columbus, OH (United States); Oak Ridge National Laboratory, Oak Ridge, TN (United States); Lim, H. [Department of Materials Science and Engineering, The Ohio State University, Columbus, OH (United States); Sandia National Laboratories, Albuquerque, NM (United States); Collings, E.W. [Department of Materials Science and Engineering, The Ohio State University, Columbus, OH (United States)

    2016-01-27

    The heat treatment, tensile testing, and bulge testing of Cu and Nb tubes has been carried out to gain experience for the subsequent hydroforming of Nb tube into seamless superconducting radio frequency (SRF) cavities for high energy particle acceleration. In the experimental part of the study samples removed from representative tubes were prepared for heat treatment, tensile testing, residual resistance ratio measurement, and orientation imaging electron microscopy (OIM). After being optimally heat treated Cu and Nb tubes were subjected to hydraulic bulge testing and the results analyzed. In the final part of the study finite-element models (FEM) incorporating constitutive (stress–strain) relationships analytically derived from the tensile and bulge tests, respectively, were used to replicate the bulge test. As expected, agreement was obtained between the experimental bulge parameters and the FEM model based on the bulge-derived constitutive relationship. Not so for the FEM model based on tensile-test data. It is concluded that a constitutive relationship based on bulge testing is necessary to predict a material's performance under hydraulic deformation.

  18. Bulge testing of copper and niobium tubes for hydroformed RF cavities

    International Nuclear Information System (INIS)

    Kim, H.S.; Sumption, M.D.; Susner, M.A.; Lim, H.; Collings, E.W.

    2016-01-01

    The heat treatment, tensile testing, and bulge testing of Cu and Nb tubes has been carried out to gain experience for the subsequent hydroforming of Nb tube into seamless superconducting radio frequency (SRF) cavities for high energy particle acceleration. In the experimental part of the study samples removed from representative tubes were prepared for heat treatment, tensile testing, residual resistance ratio measurement, and orientation imaging electron microscopy (OIM). After being optimally heat treated Cu and Nb tubes were subjected to hydraulic bulge testing and the results analyzed. In the final part of the study finite-element models (FEM) incorporating constitutive (stress–strain) relationships analytically derived from the tensile and bulge tests, respectively, were used to replicate the bulge test. As expected, agreement was obtained between the experimental bulge parameters and the FEM model based on the bulge-derived constitutive relationship. Not so for the FEM model based on tensile-test data. It is concluded that a constitutive relationship based on bulge testing is necessary to predict a material's performance under hydraulic deformation.

  19. Forming limit diagram of aluminum AA6063 tubes at high temperatures by bulge tests

    International Nuclear Information System (INIS)

    Hashemi, Seyed Jalal; Naeini, Hassan Moslemi; Liaghat, Gholamhossein; Tafti, Rooholla Azizi; Rahmani, Farzad

    2014-01-01

    A free bulge test and ductile fracture criteria were used to obtain the forming limit diagrams (FLD) of aluminum alloy AA6063 tubes at high temperatures. Ductile fracture criteria were calibrated using the results of uniaxial tension tests at various elevated temperatures and different strain rates through adjusting the Zener-Holloman parameter. High temperature free bulge test of tubes was simulated in finite element software Abaqus, and tube bursting was predicted using ductile fracture criteria under different loading paths. FLDs which were obtained from finite element simulation were compared to experimental results to select the most accurate criterion for prediction of forming limit diagram. According to the results, all studied ductile fracture criteria predict similarly when forming condition is close to the uniaxial tension, while Ayada criterion predicts the FLD at 473 K and 573 K very well.

  20. Forming limit diagram of aluminum AA6063 tubes at high temperatures by bulge tests

    Energy Technology Data Exchange (ETDEWEB)

    Hashemi, Seyed Jalal; Naeini, Hassan Moslemi; Liaghat, Gholamhossein [Tarbiat Modares University, Tehran (Iran, Islamic Republic of); Tafti, Rooholla Azizi [Yazd University, Yazd (Iran, Islamic Republic of); Rahmani, Farzad [Kar Higher Education Institute, Qazvin (Iran, Islamic Republic of)

    2014-11-15

    A free bulge test and ductile fracture criteria were used to obtain the forming limit diagrams (FLD) of aluminum alloy AA6063 tubes at high temperatures. Ductile fracture criteria were calibrated using the results of uniaxial tension tests at various elevated temperatures and different strain rates through adjusting the Zener-Holloman parameter. High temperature free bulge test of tubes was simulated in finite element software Abaqus, and tube bursting was predicted using ductile fracture criteria under different loading paths. FLDs which were obtained from finite element simulation were compared to experimental results to select the most accurate criterion for prediction of forming limit diagram. According to the results, all studied ductile fracture criteria predict similarly when forming condition is close to the uniaxial tension, while Ayada criterion predicts the FLD at 473 K and 573 K very well.

  1. Improvement in reliability and accuracy of heater tube eddy current testing by integration with an appropriate destructive test

    International Nuclear Information System (INIS)

    Giovanelli, F.; Gabiccini, S.; Tarli, R.; Motta, P.

    1988-01-01

    A specially developed destructive test is described showing how the reliability and accuracy of a non-destructive technique can be improved if it is suitably accompanied by an appropriate destructive test. The experiment was carried out on samples of AISI 304L tubes from the low-pressure (LP) preheaters of a BWR 900 MW nuclear plant. (author)

  2. Fireside corrosion testing of candidate superheater tube alloys, coatings, and claddings -- Phase 2 field testing

    Energy Technology Data Exchange (ETDEWEB)

    Blough, J.L.; Seitz, W.W.; Girshik, A. [Foster Wheeler Development Corp., Livingston, NJ (United States)

    1998-06-01

    In Phase 1 of this project, laboratory experiments were performed on a variety of developmental and commercial tubing alloys and claddings by exposing them to fireside corrosion tests which simulated a superheater or reheater in a coal-fired boiler. Phase 2 (in situ testing) has exposed samples of 347, RA85H, HR3C, RA253MA, Fe{sub 3}Al + 5Cr, Ta-modified 310, NF 709, 690 clad, 671 clad, and 800HT for up to approximately 16,000 hours to the actual operating conditions of a 250-MW, coal-fired boiler. The samples were installed on air-cooled, retractable corrosion probes, installed in the reheater cavity, and controlled to the operating metal temperatures of an existing and advanced-cycle, coal-fired boiler. Samples of each alloy were exposed for 4,483, 11,348, and 15,883 hours of operation. The present results are for the metallurgical examination of the corrosion probe samples after the full 15,883 hours of exposure. A previous topical report has been issued for the 4,483 hours of exposure.

  3. Diagnostic of corrosion defects in steam generator tubes using advanced signal processing from Eddy current testing

    International Nuclear Information System (INIS)

    Formigoni, Andre L.; Lopez, Luiz A.N.M.; Ting, Daniel K.S.

    2009-01-01

    Recently, the Brazilian Angra I PWR nuclear power plant went into a programmed shutdown for substitution of its Steam Generator (SG) which life was shortened due to stress corrosion in its tubes. The total cost of investment were around R$724 million. The signals generated during an Eddy-current Testing (ECT) inspection in SG tubes of nuclear plant allows for the localization and dimensioning of defects in the tubes. The defects related with corrosion generate complex signals that are difficult to analyze and are the most common cause in SG replacement in nuclear power plants around the world. The objective of this paper is the development of a methodology that allows for the characterization of corrosion signals by ECT inspections applied in the heat exchangers tubes of SG of a nuclear power plant. In this present work, the aim is to investigate distributed type defects by inducing controlled corrosion in sample tubes of different materials The ECT signals obtained from these samples tubes with corrosion implanted, will be analyzed using Zetec ECT equipment, the MIZ-17ET and its probes. The data acquisition will use a NI PC A/D CARD 700 card and the LabVIEW program. Subsequently, we will apply mathematical tools for signal processing like time windowed Fast Fourier transforms and Wavelets transforms, in MATLAB platform, which will allow effectiveness to remove the noises and to extract representative characteristics for the defect being analyzed. Previously obtained results as well as the proposal for the future work will be presented. (author)

  4. Circumferential tensile test method for mechanical property evaluation of SiC/SiC tube

    Energy Technology Data Exchange (ETDEWEB)

    Yu, Ju-Hyeon, E-mail: 15096018@mmm.muroran-it.ac.jp [Graduate School, Muroran Institute of Technology, 27-1, Muroran, Hokkaido (Japan); Kishimoto, Hirotatsu [Graduate School, Muroran Institute of Technology, 27-1, Muroran, Hokkaido (Japan); OASIS, Muroran Institute of Technology, 27-1, Muroran, Hokkaido (Japan); Park, Joon-soo [OASIS, Muroran Institute of Technology, 27-1, Muroran, Hokkaido (Japan); Nakazato, Naofumi [Graduate School, Muroran Institute of Technology, 27-1, Muroran, Hokkaido (Japan); Kohyama, Akira [OASIS, Muroran Institute of Technology, 27-1, Muroran, Hokkaido (Japan)

    2016-11-01

    Highlights: • NITE SiC/SiC cooling channel system to be a candidate of divertor system in future. • Hoop strength is one of the important factors for a tube. • This research studies the relationship between deformation and strain of SiC/SiC tube. - Abstract: SiC fiber reinforced/SiC matrix (SiC/SiC) composite is expected to be a candidate material for the first-wall, components in the blanket and divertor of fusion reactors in future. In such components, SiC/SiC composites need to be formed to be various shapes. SiC/SiC tubes has been expected to be employed for blanket and divertor after DEMO reactor, but there is not established mechanical investigation technique. Recent progress of SiC/SiC processing techniques is likely to realize strong, having gas tightness SiC/SiC tubes which will contribute for the development of fusion reactors. This research studies the relationship between deformation and strain of SiC/SiC tube using a circumferential tensile test method to establish a mechanical property investigation method of SiC/SiC tubes.

  5. Evaluation of tube rupture simulation test (TRUST-1) for FBR steam generators

    Energy Technology Data Exchange (ETDEWEB)

    Hayashida, Yoshihiko; Hamada, Hirotsugu [Power Reactor and Nuclear Fuel Development Corp., Oarai, Ibaraki (Japan). Oarai Engineering Center

    1996-06-01

    The intermediate water leak in an FBR Steam Generator (SG) causes a high temperature and corrosive sodium-water reaction jet. In such cases, it is necessary to evaluate the wastage and overheating rupture behavior of heat transfer tubes. Especially, in the large SG that aims at high temperature of sodium and high temperature/pressure of water, the establishment of the rational evaluation method is important. In this paper, as a basic experiment to make clear the phenomenon of overheating rupture, tests and analysis of Tube Rupture Simulation Test-1 (TRUST-1) were conducted. TRUST-1 simulates the overheating rupture of the tube made of Mod.9Cr-1Mo steel by nitrogen gas pressurization and quick induction heating. The result of TRUST-1 are as follows: (1) The breaking strength predicted by the internal pressure is larger than the tensile strength of the tube material. (2) The margin of the breaking strength from the tensile strength of the tube material has a tendency of decreasing with the heating rate, especially in the lower temperature region. (3) Using an theoretical formula that is deduced from the steady creep model and appropriate experimental coefficients that are determined by the test data, the breaking strength can be reasonably evaluated. (author)

  6. Eddy-current tests on operational evaluation of steam generator tubes in nuclear power plants

    International Nuclear Information System (INIS)

    Lopez, Luiz Antonio Negro Martin; Ting, Daniel Kao Sun

    2000-01-01

    This paper presents a worldwide research on the technical and economical impacts due to failure in tube bundles of nuclear power plant steam generators. An Eddy current non destructive test using Foucault currents for the inspection and failure detection on the tubes, and also the main type of defects. The paper also presents the signals generated by a Zetec MIZ-40 test equipment. This paper also presents a brief description of an automatic system for data analysis which is under development by using a fuzzy logic and artificial intelligence

  7. High-voltage test and training of plastic streamer tubes for the DELPHI hadron calorimeter

    International Nuclear Information System (INIS)

    Alekseev, G.D.; Cellar, S.; Khomenko, B.A.; Korytov, A.V.; Kulinich, P.A.; Micelmacher, G.V.; Sedykh, Yu.V.; Toledo, R.

    1987-01-01

    The results of high-voltage test and training of plastic streamer tubes of the DELPHI hadron calorimeter are presented. The testing technique is considered in detail. The equipment for high-voltage training consists of a mini-computer, CAMAC-electronics, a controllable high-voltage supply and a digital ampermeter. The experimental results shows that high-voltage training of streamer tubes improves their characteristics. The value of dark current decreased up to 1 μA. The operational voltage range increased by a value more than 300 V

  8. Performance demonstration tests for eddy current inspection of steam generator tubing

    International Nuclear Information System (INIS)

    Kurtz, R.J.; Heasler, P.G.; Anderson, C.M.

    1996-05-01

    This report describes the methodology and results for development of performance demonstration tests for eddy current (ET) inspection of steam generator tubes. Statistical test design principles were used to develop the performance demonstration tests. Thresholds on ET system inspection performance were selected to ensure that field inspection systems would have a high probability of detecting and and correctly sizing tube degradation. The technical basis for the ET system performance thresholds is presented in detail. Statistical test design calculations for probability of detection and flaw sizing tests are described. A recommended performance demonstration test based on the design calculations is presented. A computer program for grading the probability of detection portion of the performance demonstration test is given

  9. Performance demonstration tests for eddy current inspection of steam generator tubing

    Energy Technology Data Exchange (ETDEWEB)

    Kurtz, R.J.; Heasler, P.G.; Anderson, C.M.

    1996-05-01

    This report describes the methodology and results for development of performance demonstration tests for eddy current (ET) inspection of steam generator tubes. Statistical test design principles were used to develop the performance demonstration tests. Thresholds on ET system inspection performance were selected to ensure that field inspection systems would have a high probability of detecting and and correctly sizing tube degradation. The technical basis for the ET system performance thresholds is presented in detail. Statistical test design calculations for probability of detection and flaw sizing tests are described. A recommended performance demonstration test based on the design calculations is presented. A computer program for grading the probability of detection portion of the performance demonstration test is given.

  10. Six-Tube Freezable Radiator Testing and Model Correlation

    Science.gov (United States)

    Lilibridge, Sean T.; Navarro, Moses

    2012-01-01

    Freezable Radiators offer an attractive solution to the issue of thermal control system scalability. As thermal environments change, a freezable radiator will effectively scale the total heat rejection it is capable of as a function of the thermal environment and flow rate through the radiator. Scalable thermal control systems are a critical technology for spacecraft that will endure missions with widely varying thermal requirements. These changing requirements are a result of the spacecraft?s surroundings and because of different thermal loads rejected during different mission phases. However, freezing and thawing (recov ering) a freezable radiator is a process that has historically proven very difficult to predict through modeling, resulting in highly inaccurate predictions of recovery time. These predictions are a critical step in gaining the capability to quickly design and produce optimized freezable radiators for a range of mission requirements. This paper builds upon previous efforts made to correlate a Thermal Desktop(TM) model with empirical testing data from two test articles, with additional model modifications and empirical data from a sub-component radiator for a full scale design. Two working fluids were tested: MultiTherm WB-58 and a 50-50 mixture of DI water and Amsoil ANT.

  11. Experiment data report for semiscale Mod-1 test S-28-2 (steam generator tube rupture test)

    International Nuclear Information System (INIS)

    Patton, M.L.; Sackett, K.E.

    1977-10-01

    Recorded test data are presented for Test S-28-2 of the Semiscale Mod-1 steam generator tube rupture test series. These tests are among several Semiscale Mod-1 experiments conducted to investigate the thermal and hydraulic phenomena accompanying a hypothesized loss-of-coolant accident in a pressurized water reactor (PWR) system. Test S-28-2 was conducted from initial conditions of 15 936 kPa and 558 K to investigate the response of the Semiscale Mod-1 system to a depressurization and reflood transient following a simulated double-ended offset shear of the broken loop cold leg piping. During the test, cooling water was injected into the cold leg of the intact and broken loops to simulate emergency core coolant injection in a PWR. For Test S-28-2, accumulator injection into the intact loop hot leg was provided to simulate simulate the rupture of six steam generator tubes

  12. Improvement of the vibration of the test fuel(Type-B) with a guide tube under operational condition

    Energy Technology Data Exchange (ETDEWEB)

    Sohn, Dong Seung; Yim, Jeong Sik; Lim, I. C. [Korea Atomic Energy Research Institute, Taejon (Korea)

    1999-04-01

    The Type-B test fuel for the Hanaro has a flexible guide tube on top of the fuel to lead and guide the instrumentation wires. Depending on the flow condition in the reactor, the fuel is susceptible to vibration. During the test operation of the fuel, a fairly large amplitude vibration was observed and the possibility of flow tube contact with adjacent flow tubes, due to the excessive vibration of the fuel, and consequent wear or defect of the flow tubes were raised. Thus, to know the vibration characteristics as well as whether the flow tube contact each other, analyses of the Type-B fuel the dummy fuel were performed by BEVIRA and ANSYS. Besides the analyses, vibration tests using the dummy fuel in air and with Type-B fuel in the core at zero power under operational flow condition were executed. The results from the analyses were compared with those from tests to validate the analyses. From the deflection test of the dummy fuel in air to get the maximum displacement of the flow tube at the top, the flow tube were found to contact each other. For the prevention of the contact of the flow tubes caused by the excessive vibration of the guide tube, an additional support to the guide tube was proposed. With the additional support, analysis and in core vibration test under operational flow condition were conducted and there found to be no excessive vibration any more. 6 refs., 16 figs., 6 tabs. (Author)

  13. Pollen tube growth test (PTGT) in environmental biomonitoring and predictive radiation biology studies: problem and prospect

    International Nuclear Information System (INIS)

    Pandey, Devi D.

    2012-01-01

    In Environmental and Human Bio monitoring studies of Hazardous xenobiotics over living system particularly at cell level, it is desirable to have easy and sensitive test system like Cell Viability assay, MNT, Cell Culture photo toxicity Test, PTGT etc. Out of these the PTGT quite better than other because the in vitro culture of pollen grain can provides a sensitive indication of toxicity at cellular level, since germination and growth of pollen tube will inhibited in presence of toxic substance like DDT, Heavy metal, even Radionuclide's. This test system is easy, economical and widely accepted through out world. In PTGT pollen tube never containing Chloroplast or other plastids so pollen tube resembles animals more than a plant organ and is therefore also a suitable as model for Genotoxicity Assessment of compounds harmful to animal and humans. Lack of plastids in PT, PTGT will not identify the toxic effect of compounds that targets Non cyclic and cyclic photoposphorylation of photosynthesis. This test system valid in International Toxicity Testing Protocol. But this method is time consuming and problem in measurement of pollen tube growing in a culture medium became usually bent and make measurement difficult. Other disadvantage of this method is requirement of DMSO to dissolve test substance of low water suitability in culture medium. DMSO shown to have no effect on PTG at Concentration not more than 1% but some extent interfere with results. Values of PTG are quantified in ED50/IC50 that is the concentration of test compounds that reduces pollen tube growth to 50% of control. So PTGT could be very sensitive and easy to assess in common lab in International way. (author)

  14. Experiment data report for Semiscale Mod-1 test S-28-3 (steam generator tube rupture test)

    International Nuclear Information System (INIS)

    Gillins, R.L.; Sackett, K.E.

    1977-10-01

    Recorded test data are presented for Test S-28-3 of the Semiscale Mod-1 steam generator tube rupture test series. These tests are among several Semiscale Mod-1 experiments conducted to investigate the thermal and hydraulic phenomena accompanying a hypothesized loss-of-coolant accident in a pressurized water reactor (PWR) system. Test S-28-3 was conducted from initial conditions of 15621 kPa and 555 K to investigate the response of the Semiscale Mod-1 system to a depressurization and reflood transient following a simulated double-ended offset shear of the broken loop cold leg piping. During the test, cooling water was injected into the cold leg of the intact and broken loops to simulate emergency core coolant injection in a PWR. Twelve steam generator tube ruptures were simulated by a controlled injection from a heated accumulator into the intact loop hot leg

  15. Experiment data report for Semiscale Mod-1 Test S-28-1 (steam generator tube rupture test series)

    International Nuclear Information System (INIS)

    Collins, B.L.; Coppin, C.E.; Sackett, K.E.

    1977-10-01

    Recorded test data are presented for Test S-28-1 of the Semiscale Mod-1 steam generator tube rupture test series. These tests are among several Semiscale Mod-1 experiments conducted to investigate the thermal and hydraulic phenomena accompanying a hypothesized loss-of-coolant accident in a pressurized water reactor (PWR) system. Test S-28-1 was conducted from initial conditions of 15 767 kPa and 557 K to investigate the response of the Semiscale Mod-1 system to a depressurization and reflood transient following a simulated double-ended offset shear of the broken loop cold leg piping. During the test, cooling water was injected into the cold leg of the intact and broken loops to simulate emergency core coolant injection in a PWR. Sixty steam generator tube ruptures were simulated by a controlled injection from a heated accumulator into the intact loop hot leg

  16. Experiment data report for semiscale Mod-1 test S-28-4 (steam generator tube rupture test)

    International Nuclear Information System (INIS)

    Esparza, V.; Sackett, K.E.

    1977-10-01

    Recorded test data are presented for Test S-28-4 of the Semiscale Mod-1 steam generator tube rupture test series. These tests are among several Semiscale Mod-1 experiments conducted to investigate the thermal and hydraulic phenomena accompanying a hypothesized loss-of-coolant accident in a pressurized water reactor (PWR) system. Test S-28-4 was conducted from initial conditions of 15 646 kPa and 557 K to investigate the response of the Semiscale Mod-1 system to a depressurization and reflood transient following a simulated double-ended offset shear of the broken loop cold leg piping. During the test, cooling water was injected into the cold leg of the intact and broken loops to simulate emergency core coolant injection in a PWR. Thirty steam generator tube ruptures were simulated by a controlled injection from a heated accumulator into the intact loop hot leg

  17. Bond strength tests between silicon wafers and duran tubes (fusion bonded fluidic interconnects)

    NARCIS (Netherlands)

    Fazal, I.; Berenschot, Johan W.; de Boer, J.H.; Jansen, Henricus V.; Elwenspoek, Michael Curt

    2005-01-01

    The fusion bond strength of glass tubes with standard silicon wafers is presented. Experiments with plain silicon wafers and those coated with silicon oxide and silicon nitride are presented. Results obtained are discussed in terms of homogeneity and strength of fusion bond. High pressure testing

  18. Inhibition of Microbial Growth by Fatty Amine Catalysts from Polyurethane Foam Test Tube Plugs

    Science.gov (United States)

    Bach, John A.; Wnuk, Richard J.; Martin, Delano G.

    1975-01-01

    When polyurethane foam test tube plugs are autoclaved, they release volatile fatty amines that inhibit the growth of some microorganisms. The chemical structures of these amines were determined by the use of a gas chromatographmass spectrometer. They are catalysts used to produce the foam. The problem of contaminating growth media with toxic substances released from polymeric materials is discussed. PMID:1096816

  19. Using an indwelled test tube as a good "navigator" during enterostomy closure.

    Science.gov (United States)

    Hirose, Ryuichiro; Tojigamori, Manabu; Obata, Satoshi; Tatsuta, Kyosuke; Kawakubo, Naonori; Arima, Toru

    2012-11-01

    Surgeons often have difficulty in identifying a suitable incision line to enter the peritoneal cavity for stoma mobilization during enterostomy closure. A mini-size test tube that is preoperatively placed into the stoma can act as an efficient guide in finding a free area to enter the peritoneal cavity, by supplying efficient counter traction and a palpable marker of the intestinal wall.

  20. Optimization and testing of dried antibody tube: The EuroFlow LST and PIDOT tubes as examples

    NARCIS (Netherlands)

    V.H.J. van der Velden (Vincent); J. Flores-Montero (Juan); M. Perez-Andres; M. Martin-Ayuso (M.); Crespo, O. (Oliver); Blanco, E. (Elena); T. Kalina (Tomas); J. Philippé (Jan); Bonroy, C. (Carolien); M. de Bie (Maaike); J.G. te Marvelde (Jeroen); C. Teodosio (Cristina); Corral Mateos, A. (Alba); V. Kanderová (V.); M. van der Burg (Mirjam); Van Hoof, D. (Dennis); J.J.M. van Dongen (Jacques); A. Orfao (Alberto)

    2017-01-01

    textabstractWithin EuroFlow, we recently developed screening tubes for hematological malignancies and immune deficiencies. Pipetting of antibodies for such 8-color 12-marker tubes however is time-consuming and prone to operational mistakes. We therefore evaluated dried formats of the lymphocytosis

  1. FY 1997 Progress report on tube propagation testing of tank waste using the PRSST

    International Nuclear Information System (INIS)

    Bechtold, D.B.

    1997-01-01

    The subject of this FY 1997 progress report is tube propagation tests of actual, dried tank waste to verify the contact temperature ignition (CTI) criterion for point-source ignition in the Hanford Site waste tanks. Testing is in support of the Organic Tanks Safety Project and will help resolve safety issues with waste containing organic constituents. In FY 1997, improvements were made to the laboratory apparatus and procedures for conducting the testing, and the final testing strategy was formulated. The strategy lays out details of the tests to be performed, samples to be tested, and modes of reporting results

  2. A Study of Frequency Mixing Approaches for Eddy Current Testing of Steam Generator Tubes

    International Nuclear Information System (INIS)

    Jung, Hee Jun; Song, Sung Jin; Kim, Chang Hwan; Kim, Dae Kwang

    2009-01-01

    The multifrequency eddy current testing(ECT) have been proposed various frequency mixing algorithms. In this study, we compare these approaches to frequency mixing of ECT signals from steam generator tubes; time-domain optimization, discrete cosine transform-domain optimization. Specifically, in this study, two different frequency mixing algorithms, a time-domain optimization method and a discrete cosine transform(DCT) optimization method, are investigated using the experimental signals captured from the ASME standard tube. The DCT domain optimization method is computationally fast but produces larger amount of residue.

  3. Testing external surface of fuel element tubes for power nuclear reactors

    International Nuclear Information System (INIS)

    Naugol'nykh, O.G.; Nelyubin, Yu.V.

    1987-01-01

    Optical methods are regarded perspective for discovery and detection of flaws of external surfaces of fuel element tubes. The TV method has highest information content among them. Two mock-ups of facilities based on the TV method using a ''dissector'' type TV device and a TV tube with charge accumulation (vidikon) have been developed. It is concluded that complex testing - combination of ultrasonic, photoelectric and TV methods in a facility is necessary for discovery and analysis of the whole variety of flaws, though sensitivity of the TV method is enough for disclosure of all the main defects

  4. Signal Characteristics of Eddy Current Test for Intergranular Attack of Steam Generator Tubes

    International Nuclear Information System (INIS)

    Choi, Myung Sik; Lee, Deok Hyun; Han, Jung Ho; Hur, Do Haeng; Cho, Se Gon; Yim, Chang Jae

    2002-01-01

    Because intergranular attack (IGA), one of the localized corrosion forms occurring on steam generator tubes, can not be fabricated by an electric discharge machining method, there are few data for the eddy current test (ECT) characteristics of IGA. In this paper, the characteristics of eddy current signals are evaluated using nonexpanded tubes with IGA defects formed in 0.1 M sodium tetrathionate solution at 40 .deg. C. The detectability and sizing accuracy of IGA were discussed in terms of the coil type and frequency of the ECT probes

  5. Recent Advances in Simulation of Eddy Current Testing of Tubes and Experimental Validations

    Science.gov (United States)

    Reboud, C.; Prémel, D.; Lesselier, D.; Bisiaux, B.

    2007-03-01

    Eddy current testing (ECT) is widely used in iron and steel industry for the inspection of tubes during manufacturing. A collaboration between CEA and the Vallourec Research Center led to the development of new numerical functionalities dedicated to the simulation of ECT of non-magnetic tubes by external probes. The achievement of experimental validations led us to the integration of these models into the CIVA platform. Modeling approach and validation results are discussed here. A new numerical scheme is also proposed in order to improve the accuracy of the model.

  6. Eddy-current testing of nuclear fuel cladding tubes using tilted encircling coil system, 1

    International Nuclear Information System (INIS)

    Yin, Renzhong; Sekine, Kazuyoshi; Shimizu, Hisaji; Tsukui, Kazushige; Urata, Megumu.

    1989-01-01

    The eddy current testing method with external encircling-coils has been widely used as a standard technique for inspection of defects in irradiated zircaloy cladding tubes. In this inspection, the systematic procedure to reliably characterize defects is required. This paper describes the newly developed external tilted encircling-coil system, in which the coil axis is inclined by an angle α to the sample tube axis, for reliable determination of the sort, location and size of defects. As the results of experimental work concerning some kinds of artificial defects in zircaloy cladding tubes using newly designed tilted coil system, an adaptable general-procedure for characterization of defects has been proposed. Furthermore, it has been confirmed that in the case of smaller tilt angles of coil, the signal-to noise ratio for defect response in this coil system is approximately equal to that of ordinary encircling coil system. (author)

  7. In-pile Creep Tests of Zircaloy Tubing in the Studsvik R2 Reactor. Final Report

    International Nuclear Information System (INIS)

    Tomani, Hans; Lindeloew, Ulf

    2000-12-01

    In this report are presented the findings of a prototype creep test on Zr4 guide tube specimens exposed in-pile and out-of-pile and stressed by constant bending moments. The calculated initial deflection curvature caused by the applied bending moment agrees very well with the measured initial values. Furthermore, the measurement results show excellent consistency. The dominant impact of neutron irradiation is clearly demonstrated. After 3 cycles (∼1300 hours) the irradiation creep is 4 times as large as the thermal creep. This is the case at least when fresh tube material is used. Irradiation creep progresses steadily, but the creep rate is not quite constant during the 3 irradiation cycles. The thermal creep, on the other hand, quickly saturates and there is hardly any further deflection after the second cycle for the specimen situated above the core. A limitation with the rig has been that the tube deflection became limited by the rig carrier body of the rig in the neutron flux (core) that disqualified the results of a fourth irradiation cycle actually performed in the fall of 1998. The test method appears to be suitable for testing the bending creep of different guide tube materials or designs under PWR conditions

  8. Applied research for profilometric testing of the state of interior surfaces in heat exchanger tubes

    International Nuclear Information System (INIS)

    Gyongyosi, Tiberiu; Panaitescu, Valeriu Nicolae

    2009-01-01

    Generally, the surface flaws identified at heat exchangers tubing are characteristic for the heat secondary systems, located on the external surfaces of the heat exchanger tubes and are mostly the results of the ageing phenomena in systems operation. The tests performed, with the impressing replicating device confirmed the applicability of the technique, functionality of the device and resulted in replicas on metal support, these being the hard copy of the negative of the test tube surface, allowing the profile measurement. The visual inspection of the replicas on the metallic support gives information about the surface geometry replicated, pointing out the marks, which belong to the same area under observation. The minimum and maximum values for the depth of the channel worked out in the inner test tube wall have been determined by profile graphic measurement on the replicas. The paper presents the structural and functional description of the experimental devices. The first results and some conclusions are also included. Two patent applications were submitted at State Office for Inventions and Trademarks (OSIM) covering the original data to protect royalty: 'The local pit flaws, scratches, incipient micro-cracks replicating device on inner cylindrical surfaces', under no. A/00299/17.04.2008 and 'The annular local flaw, incipient micro-cracks replicating device on inner cylindrical surface' under no. A/00300/17.04.2008

  9. Method and apparatus for testing closed-end tubes in heat exchangers of nuclear reactors and the like

    International Nuclear Information System (INIS)

    Seyd, G.; Bergbauer, A.; Paulsen, U.

    1975-01-01

    A description is given of a test stopper which is insertable into a tube closed at one end for testing the tightness of the tube with a fluid under pressure, the tube being in a heat exchanger of a nuclear reactor or the like. The test stopper includes a tubular outer jacket that is expandable outwardly to tightly seat the stopper in the tube. The stopper also has front and back end-face members joined to the ends of the outer jacket to define a closed space within the jacket. With the stopper inserted into the tube, the front end-face member and the closed end portion of the tube define a closed inner region of the tube. An inner tubular member, disposed within the outer jacket, partitions the closed space within the jacket into an annular outer chamber and a cylindrical inner chamber. A pressure-fluid supply selectively supplies fluid to the chambers. The outer jacket expands in response to fluid admitted to the annular chamber and the front end-face member has a through bore to admit fluid under pressure to the inner region of the tube. A method of testing of such a tube with a fluid under pressure includes inserting the test stopper into the tube and then expanding the outer jacket of the stopper to seat the stopper firmly in the tube. A fluid under pressure is directed through the stopper and into the closed region defined by the front end-face member of the stopper and the closed end portion of the tube. The pressure of the fluid introduced into this closed region is monitored for detecting a leak in the closed-end tube

  10. IR1 flow tube and In-Pile Test Section Pressure drop test for the 3-Pin Fuel Test Loop

    Energy Technology Data Exchange (ETDEWEB)

    Lee, H. H.; Park, K. N.; Chi, D. Y.; Sim, B. S.; Park, S. K.; Lee, J. M.; Lee, C. Y.; Kim, H. N

    2006-02-15

    The in-pile Section (IPS) of 3-pin Fuel Test Loop(FTL) shall be installed in the vertical hole call IR1 of HANARO reactor core. In order to verify the pressure drop and flow rate both the inside region of IPS at the annular region between IPS and IR1 flow tube, a pressure drop was measured by varing the flow rate on both regions. The measured pressure drop in the annular region is 209kpa at 14.9kg/s which meets the limiting condition of operation of 200kpa. The measured pressure drop in side the IPS becomes 260.25kpa which is lower than the designed value of 306.65kpa. As the pressure drop is lower than the design value, it is quite conservative from the safety and operating point of view.

  11. First joint test beam of CMS Drift Tubes (DT) and Resistive Plate Chambers (RPC)

    CERN Multimedia

    Paolo Giacomelli

    2001-01-01

    The first full size muon drift tube chamber ever built for the CMS barrel with the final cell design (constructed at CIEMAT, Madrid) was succesfully tested with a muon beam in September 2001 at the Gamma Irradiation Facility (GIF) at CERN. For the first time also both muon detectors for the CMS barrel (DT + RPC) were coupled together. The results of this test were fully succesful and confirmed the excellent performance of both detectors together in a radiation environment.

  12. Adaptation, testing and application of the two-dimensional FE computer program system for steam generator tube testing

    International Nuclear Information System (INIS)

    Betzold, K.

    1987-01-01

    The 2d-FE computing program system, taken over by EPRI, is used for the improvement of the eddy current test of steam generator heating tubes. The investigations focus on test tasks in the area of the tube plate and the scrap mark; among them: accumulation of mud in the cracking area and above the tube plate; circulating slots with and without accumulation of mud. The interaction of the factors of influence given by the test object and the parameters selectable by the tester as for example coil length and base space for absolute coils and differential coils as well as test frequencies are calculated and the form of the signal locus curves and the dynamic curves are listed in a sample catalogue. It is demonstrated with selected examples that the sample catalogue contributes to the test-specific design of the coil and to the choice of the test frequencies; interpretation of measured signals; deepening of the knowledge of the physical processe in eddy current tests. (orig./HP) [de

  13. Calculation of fuel element temperature TRIGA 2000 reactor in sipping test tubes using CFD

    International Nuclear Information System (INIS)

    Sudjatmi KA

    2013-01-01

    It has been calculated the fuel element temperature in the sipping test of Bandung TRIGA 2000 reactor. The calculation needs to be done to ascertain that the fuel element temperatures are below or at the limit of the allowable temperature fuel elements during reactor operation. ensuring that the implementation of the test by using this device, the temperature is still within safety limits. The calculation is done by making a model sipping test tubes containing a fuel element surrounded by 9 fuel elements. according to the position sipping test tubes in the reactor core. by using Gambit. Dimensional model adapted to the dimensions of the tube and the fuel element in the reactor core of Bandung TRIGA 2000 reactor. Sipping test Operation for each fuel element performed for 30 minutes at 300 kW power. Calculations were performed using CFD software and as input adjusted parameters of TRIGA 2000 reactor. Simulations carried out on the operation of the 30, 60, 90, 120, 150, 180 and 210 minutes. The calculation result shows that the temperature of the fuel in tubes sipping test of 236.06 °C, while the temperature of the wall is 87.58 °C. The maximum temperature in the fuel center of TRIGA 2000 reactor in normal operation is 650 °C. and the boiling is not allowed in the reactor. So it can be concluded that the operation of the sipping test device are is very safe because the fuel center temperature is below the temperature limits the allowable fuel under normal operating conditions as well as the fuel element wall temperature is below the boiling temperature of water. (author)

  14. Preanalytical errors in primary healthcare: a questionnaire study of information search procedures, test request management and test tube labelling.

    Science.gov (United States)

    Söderberg, Johan; Brulin, Christine; Grankvist, Kjell; Wallin, Olof

    2009-01-01

    Most errors in laboratory medicine occur in the preanalytical phase and are the result of human mistakes. This study investigated information search procedures, test request management and test tube labelling in primary healthcare compared to the same procedures amongst clinical laboratory staff. A questionnaire was completed by 317 venous blood sampling staff in 70 primary healthcare centres and in two clinical laboratories (response rate = 94%). Correct procedures were not always followed. Only 60% of the primary healthcare staff reported that they always sought information in the updated, online laboratory manual. Only 12% reported that they always labelled the test tubes prior to drawing blood samples. No major differences between primary healthcare centres and clinical laboratories were found, except for test tube labelling, whereby the laboratory staff reported better practices. Re-education and access to documented routines were not clearly associated with better practices. The preanalytical procedure in the surveyed primary healthcare centres was associated with a risk of errors which could affect patient safety. To improve patient safety in laboratory testing, all healthcare providers should survey their preanalytical procedures and improve the total testing process with a systems perspective.

  15. Five Tubes Rupture at Cold Side of Steam Generator Simulation Test Report Using the ATLAS

    International Nuclear Information System (INIS)

    Kang, Kyoung Ho; Park, Hyun Sik; Cho, Seok

    2010-12-01

    In this study, a postulated SGTR event of the APR1400 was experimentally investigated with the ATLAS. In order to simulate a double-ended rupture of five U-tubes in the APR1400, the SGTR-CL-02 test was performed with the ATLAS. The main objectives of this test were not only to provide a physical insight into the system response of the APR1400 during the SGTR but also to produce integral effect experimental data to validate the safety analysis code. In the present report, major thermal-hydraulic phenomena such as the system pressures, the collapsed water levels, and the break flow rate were presented and discussed. Compared to the case of a single U-tube rupture test, opening frequency of the MSSVs in the intact steam generator (SG-2) was highly reduced after 500 seconds in the present SGTR-CL-02 test. Large discharge of the primary inventory resulted in rapid depressurization of the primary system and consequently early injection of the SIP. Supply of cold ECC water by the SIPs reduced the energy transfer to the secondary side compared with the single U-tube rupture case. Less heat transfer to the secondary side had more influence on the secondary pressure of the affected steam generator than the break flow. This integral effect test data will be used to evaluate the prediction capability of existing safety analysis codes of the MARS and the RELAP5 as well as the SPACE code

  16. Five Tubes Rupture at Hot Side of Steam Generator Simulation Test Report Using the ATLAS

    International Nuclear Information System (INIS)

    Kang, Kyoung Ho; Park, Hyun Sik; Cho Seok

    2010-12-01

    In this study, a postulated SGTR event of the APR1400 was experimentally investigated with the ATLAS. In order to simulate a double-ended rupture of five U-tubes in the APR1400, the SGTR-HL-05 test was performed with the ATLAS. The main objectives of this test were not only to provide a physical insight into the system response of the APR1400 during the SGTR but also to produce integral effect experimental data to validate the SPACE code. In the present report, major thermal-hydraulic phenomena such as the system pressures, the collapsed water levels, and the break flow rate were presented and discussed. On the contrary to the case of a single U-tube rupture test, the MSSV of the intact steam generator was not opened any more after 1500 seconds in the present SGTR-HL-05 test. Large discharge of the primary inventory resulted in rapid depressurization of the primary system and consequently early injection of the SIP. Supply of cold ECC water by the SIPs reduced the energy transfer to the secondary side compared with the single U-tube rupture case. Less heat transfer to the secondary side had more influence on the secondary pressure of the affected steam generator than the break flow. This integral effect test data will be used to evaluate the prediction capability of existing safety analysis codes of the MARS and the RELAP5 as well as the SPACE code

  17. Progranulin haploinsufficiency causes biphasic social dominance abnormalities in the tube test.

    Science.gov (United States)

    Arrant, A E; Filiano, A J; Warmus, B A; Hall, A M; Roberson, E D

    2016-07-01

    Loss-of-function mutations in progranulin (GRN) are a major autosomal dominant cause of frontotemporal dementia (FTD), a neurodegenerative disorder in which social behavior is disrupted. Progranulin-insufficient mice, both Grn(+/-) and Grn(-/-) , are used as models of FTD due to GRN mutations, with Grn(+/-) mice mimicking the progranulin haploinsufficiency of FTD patients with GRN mutations. Grn(+/-) mice have increased social dominance in the tube test at 6 months of age, although this phenotype has not been reported in Grn(-/-) mice. In this study, we investigated how the tube test phenotype of progranulin-insufficient mice changes with age, determined its robustness under several testing conditions, and explored the associated cellular mechanisms. We observed biphasic social dominance abnormalities in Grn(+/-) mice: at 6-8 months, Grn(+/-) mice were more dominant than wild-type littermates, while after 9 months of age, Grn(+/-) mice were less dominant. In contrast, Grn(-/-) mice did not exhibit abnormal social dominance, suggesting that progranulin haploinsufficiency has distinct effects from complete progranulin deficiency. The biphasic tube test phenotype of Grn(+/-) mice was associated with abnormal cellular signaling and neuronal morphology in the amygdala and prefrontal cortex. At 6-9 months, Grn(+/-) mice exhibited increased mTORC2/Akt signaling in the amygdala and enhanced dendritic arbors in the basomedial amygdala, and at 9-16 months Grn(+/-) mice exhibited diminished basal dendritic arbors in the prelimbic cortex. These data show a progressive change in tube test dominance in Grn(+/-) mice and highlight potential underlying mechanisms by which progranulin insufficiency may disrupt social behavior. © 2016 John Wiley & Sons Ltd and International Behavioural and Neural Genetics Society.

  18. Some results of the 50 MW straight tube steam generator test in the TNO 50 MW SCTF at Hengelo

    International Nuclear Information System (INIS)

    Ludwig, P.W.P.H.; Hus, B.M.

    1975-01-01

    A prototype 50 MW straight tube steam generator has been tested during more than 3000 hours under operating conditions. The steady state, transient and stability behaviour were tested. The most remarkable results of the experiments are given. (author)

  19. Some results of the 50 MW straight tube steam generator test in the TNO 50 MW SCTF at Hengelo

    Energy Technology Data Exchange (ETDEWEB)

    Ludwig, P W.P.H.; Hus, B M

    1975-07-01

    A prototype 50 MW straight tube steam generator has been tested during more than 3000 hours under operating conditions. The steady state, transient and stability behaviour were tested. The most remarkable results of the experiments are given. (author)

  20. [Efficient and rapid non-test tube cloning of Jatropha curcas].

    Science.gov (United States)

    Wang, Zhao-Yu; Lin, Jing-Ming; Xu, Zeng-Fu

    2007-08-01

    To develop a new technique for efficient and rapid non-test tube cloning of the medicinal and energy- producing plant Jatropha curcas. Using the mini-stem fragment (2-3 cm) of Jatropha curcas with merely one axillary bud as the explant, the effect of an auxin IBA concentration on the plantlet regeneration was studied. When treated with 1 mg/LIBA for 1h, the explants showed the most rapid propagation. The mini-stem fragments high root regeneration ratio (96.7%), short root regeneration period (18.2-/+2.0 d), large number of new roots per explant (6.3-/+1.8), and long total root length (6.8-/+3.5 cm), demonstrating that this technique can be a simple and efficient method for rapid non-test tube cloning of Jatropha curcas of potential industrial value.

  1. An integrated automatic system for the eddy-current testing of the steam generator tubes

    Energy Technology Data Exchange (ETDEWEB)

    Woo, Hee Gon; Choi, Seong Su [Korea Electric Power Corp. (KEPCO), Taejon (Korea, Republic of). Research Center

    1995-12-31

    This research project was focused on automation of steam generator tubes inspection for nuclear power plants. ECT (Eddy Current Testing) inspection process in nuclear power plants is classified into 3 subprocesses such as signal acquisition process, signal evaluation process, and inspection planning and data management process. Having been automated individually, these processes were effectively integrated into an automatic inspection system, which was implemented in HP workstation with expert system developed (author). 25 refs., 80 figs.

  2. An integrated automatic system for the eddy-current testing of the steam generator tubes

    Energy Technology Data Exchange (ETDEWEB)

    Woo, Hee Gon; Choi, Seong Su [Korea Electric Power Corp. (KEPCO), Taejon (Korea, Republic of). Research Center

    1996-12-31

    This research project was focused on automation of steam generator tubes inspection for nuclear power plants. ECT (Eddy Current Testing) inspection process in nuclear power plants is classified into 3 subprocesses such as signal acquisition process, signal evaluation process, and inspection planning and data management process. Having been automated individually, these processes were effectively integrated into an automatic inspection system, which was implemented in HP workstation with expert system developed (author). 25 refs., 80 figs.

  3. Influence of Aroclor 1242 Concentration on Polychlorinated Biphenyl Biotransformations in Hudson River Test Tube Microcosms

    Science.gov (United States)

    Fish, K. M.

    1996-01-01

    When 93.3 to 933 (mu)mol of Aroclor 1242 per kg was added to Hudson River sediment test tube microcosms, the rates of polychlorinated biphenyl biotransformations increased with increasing Aroclor 1242 concentration after a 4- to 8-week acclimation period. In contrast, when 37.3 (mu)mol of Aroclor 1242 per kg was added, polychlorinated biphenyl biotransformations occurred at slow constant rates. PMID:16535387

  4. High heat flux tests at divertor relevant conditions on water-cooled swirl tube targets

    International Nuclear Information System (INIS)

    Schlosser, J.; Boscary, J.

    1994-01-01

    High heat flux experiments were performed to provide a technology for heat flux removal under NET/ITER relevant conditions. The water-cooled rectangular test sections were made of hardened copper with a stainless steel twisted tape installed inside a circular channel and one-side heated. The tests aimed to investigate the heat transfer and the critical heat flux in the subcooled boiling regime. A CHF data base of 63 values was established. Test results have shown the thermalhydraulic ability of swirl tubes to sustain an incident heat flux up to a 30 MW.m -2 range. (author) 10 refs.; 7 figs

  5. The Aphrodite boiling crisis program. Analysis of CHF tests performed on a vertical tube

    International Nuclear Information System (INIS)

    Souyri, A.; Conan, S.; Portesse, A.; Tremblay, D.

    1992-09-01

    In order to develop a comprehensive modelling of the boiling crisis phenomenon, the APHRODITE experimental program has been set up at ELECTRICITE DE FRANCE. Aiming at a better mechanistic understanding of this phenomenon, this program will investigate the influence of the experimental conditions (among which the mockup geometry and the boundary conditions) and the two-phase flow patterns via void fraction distributions. It has involved the construction of a R12 test loop, which can deliver a large thermal-hydraulic parameter ranges, and the development of a gamma-ray tomograph. The first experiments have been carried out on a vertical Inconel tube, 6 meters long with a bore diameter of 13 mm and a thickness of 0.5 mm. This electrically heated test section is heavily instrumented with 168 thermocouples welded along the tube, on its outer surface. After a refined calibration of the experimental procedure, a critical heat flux data bank has been collected within large pressure, mass velocity and critical steam quality ranges. These results are firstly compared with other CHF data obtained in similar conditions. Then several empirical correlations and a theoretical model for similar prediction in tubes are tested against these data

  6. A cryogenic tensile testing apparatus for micro-samples cooled by miniature pulse tube cryocooler

    International Nuclear Information System (INIS)

    Chen, L B; Liu, S X; Gu, K X; Zhou, Y; Wang, J J

    2015-01-01

    This paper introduces a cryogenic tensile testing apparatus for micro-samples cooled by a miniature pulse tube cryocooler. At present, tensile tests are widely applied to measure the mechanical properties of materials; most of the cryogenic tensile testing apparatus are designed for samples with standard sizes, while for non-standard size samples, especially for microsamples, the tensile testing cannot be conducted. The general approach to cool down the specimens for tensile testing is by using of liquid nitrogen or liquid helium, which is not convenient: it is difficult to keep the temperature of the specimens at an arbitrary set point precisely, besides, in some occasions, liquid nitrogen, especially liquid helium, is not easily available. To overcome these limitations, a cryogenic tensile testing apparatus cooled by a high frequency pulse tube cryocooler has been designed, built and tested. The operating temperatures of the developed tensile testing apparatus cover from 20 K to room temperature with a controlling precision of ±10 mK. The apparatus configurations, the methods of operation and some cooling performance will be described in this paper. (paper)

  7. Ion beam characteristics of the controlatron/zetatron family of the gas filled neutron tubes

    Energy Technology Data Exchange (ETDEWEB)

    Berg, R.S.; Shope, L.A.; O' Neal, M.L.; Boers, J.E.; Bickes, R.W. Jr.

    1981-03-01

    A gas filled tube used to produce a neutron flux with the D(T,He/sup 4/)n reaction is described. Deuterium and tritium ions generated in a reflex discharge are extracted and accelerated to 100 keV by means of an accelerator electrode onto a deutero-tritide target electrode. The electrodes are designed to focus the ion beam onto the target. Total tube currents consisting of extracted ions, unsuppressed secondary electrons, and ions generated by interactions with the background gas are typically 100 mA. The characteristics of the extracted ion beam are discussed. Accelerating voltages greater than 50 kV are required to focus the beam through the accelerator aperture for configurations that give beams with the proper energy density onto the target. The perveance of the beam is discussed. Maximum perveance values are 2 to 20 nanopervs. Tube focusing and neutron production characteristics are described.

  8. Heat transfer test in a tube using CO2 at supercritical pressures

    International Nuclear Information System (INIS)

    Kim, Hwan Yeol; Kim, Hyungrae; Song, Jin Ho; Cho, Bong Hyun; Bae, Yoon Yeong

    2005-01-01

    Heat transfer test facility, which is named as SPHINX (Supercritical Pressure Heat Transfer Investigation for NeXt Generation), has been constructed in KAERI for the study of heat transfer and pressure drop characteristics in a single tube, single rod and rod bundle at supercritical CO 2 conditions. The tests with supercritical water are difficult it terms of cost and effort, since the critical pressure and temperature of water are as high as 22.12 MPa and 374.14degC. As a substitute for water, CO 2 is selected for the test since the critical pressure and temperature of CO 2 are 7.38 MPa and 31.05degC that are much lower than those of water. This paper describes the design characteristics of the SPHINX and the experimental investigations on the heat transfer and pressure drop of a vertical single tube with an inside diameter of 4.4 mm with upward flow of supercritical CO 2 . The geometry of the single tube is the same as that of Kyushu University test performed with Freon (R22) for the direct comparison of a medium effect. The tests were performed with various heat and mass fluxes at a given pressure. The range of mass flux is 400∼1200 kg/m 2 s and the heat flux is chosen up to 150 kW/m 2 . The selected pressure are 7.75, 8.12, and 8.85 MPa. The test results are investigated and compared with the previous tests. (author)

  9. Measurement of the viscoelastic compliance of the eustachian tube using a modified forced-response test.

    Science.gov (United States)

    Ghadiali, Samir N; Federspiel, William J; Swarts, J Douglas; Doyle, William J

    2002-01-01

    Eustachian tube compliance (ETC) was suggested to be an important determinate of function. Previous attempts to quantify ETC used summary measures that are not clearly related to the physical properties of the system. Here, we present a new method for measuring ETC that conforms more closely to the engineering definition of compliance. The forced response test was modified to include oscillations in applied flow after the forced tubal opening. Pressure and flow were recorded during the standard and modified test in 12 anesthetized cynomolgus monkeys. The resulting pressure-flow, hysteresis loops were compared with those predicted by a simple fluid-structure model of the Eustachian tube with linear-elastic or viscoelastic properties. The tubal compliance index (TCI) and a viscoelastic compliance (C(v)) were calculated from these data for each monkey. The behavior of a viscoelastic, but not a linear elastic model accurately reproduced the experimental data for the monkey. The TCI and C(v) were linearly related, but the shared variance in these measures was only 63%. This new method for measuring ETC captures all information contained in the traditional TCI, but also provides information regarding the contribution of wall viscosity to Eustachian tube mechanics.

  10. Application of numerical analysis techniques to eddy current testing for steam generator tubes

    International Nuclear Information System (INIS)

    Morimoto, Kazuo; Satake, Koji; Araki, Yasui; Morimura, Koichi; Tanaka, Michio; Shimizu, Naoya; Iwahashi, Yoichi

    1994-01-01

    This paper describes the application of numerical analysis to eddy current testing (ECT) for steam generator tubes. A symmetrical and three-dimensional sinusoidal steady state eddy current analysis code was developed. This code is formulated by future element method-boundary element method coupling techniques, in order not to regenerate the mesh data in the tube domain at every movement of the probe. The calculations were carried out under various conditions including those for various probe types, defect orientations and so on. Compared with the experimental data, it was shown that it is feasible to apply this code to actual use. Furthermore, we have developed a total eddy current analysis system which consists of an ECT calculation code, an automatic mesh generator for analysis, a database and display software for calculated results. ((orig.))

  11. Test of a proportional tube modulus used to localize the electromagnetic showers in a calorimeter

    International Nuclear Information System (INIS)

    Lees, J.-P.

    1981-01-01

    In this work are given results of a test in an electron-hadron beam (5-92 GeV) of the prototype of a position detector. This position detector consists of proportional tubes with charge division readout; it will be used in the end cap electromagnetic calorimeter ('bouchon') of the UA1 experiment at CERN (pantip collisions at a center of mass energy of 540 GeV). This detector gives the position of the showers, and also a coarse value of their energy. Results about properties of the tubes (saturation phenomena, position and energy accuracies) and, then, results about the development of high energy electromagnetic showers in lead-plastic sandwich are given here [fr

  12. Materials tests and analyses of Faraday shield tubes for ICRF [ion cyclotron resonant frequency] antennas

    International Nuclear Information System (INIS)

    King, J.F.; Baity, F.W.; Hoffman, D.J.; Walls, J.C.; Taylor, D.J.

    1988-01-01

    The ion cyclotron resonant frequency (ICRF) antennas for heating fusion plasmas require careful analysis of the materials selected for the design and the successful fabrication of high integrity braze bonds. Graphite tiles are brazed to Inconel 625 Faraday shield tubes to protect the antenna from the plasma. The bond between the graphite and Inconel tube is difficult to achieve due to the different coefficients of thermal expansion. A 2-D stress analysis showed the graphite could be bonded to Inconel with a Ag-Cu-Ti braze alloy without cracking the graphite. Brazing procedures and nondestructive examination methods have been developed for these joints. This paper presents the results of our joining development and proof testing. 2 refs., 3 figs

  13. Fatigue testing on samples from Zircaloy-4 tubes type SEU-43

    International Nuclear Information System (INIS)

    Olaru, V.; Ionescu, V.; Nitu, A.; Ionescu, D.; Voicu, F.

    2016-01-01

    The paper presents the testing of samples worked from Zicaloy-4 tubes (as-received.. metallurgical state), utilized in the composition of the CANDU SEU-43 fuel bundle. These tests are intended to simulate their behaviour in a power cycling process inside the reactor. The testing process is of low cycle fatigue type, done outside of the reactor, on ''C-ring'' samples, cut along the transversal direction. These samples are tested at 1%, 2% and 3% amplitude deformation, at room temperature. The calibration curves for both types of tube (small and big diameter) are determined by using the finite element analyses with the ANSYS computer code. The cycling test results are in the form of a fatigue life curve (N-e) for zircaloy-4 used in the SEU-43 fuel bundle. The curve is determined by the experimental dependency between the number of cycles to fracture and the deformation amplitude. The low cycle fatigue mechanical tests done at room temperature together with electronic microscopy analyses have reflected the characteristic behaviour of the zircaloy-4 metal in the given environment conditions. (authors)

  14. Long term testing of materials for tube shielding, stage 2; Laangtidsprovning av tubskyddsmaterial, etapp 2

    Energy Technology Data Exchange (ETDEWEB)

    Norling, Rikard; Hjoernhede, Anders; Mattsson, Mattias

    2012-02-15

    temperature. It varies from a few months to several years. The cost of replacing tube shielding is significant, which calls for improved materials. In a previous study [1] various materials have been tested in the WtE CFB-boiler P14 at Haendeloe in Norrkoeping, Sweden. The study showed that several materials may be cost effective candidates for replacing 253MA, but the test period was too short for safe predictions. This work includes exposures at the same position, but with extended test period up to almost 12000 h to verify the previous results. In addition results from exposures in the WtE CFB-boiler Hoegdalen P6 in Stockholm, Sweden is included. This boiler suffers in particular from severe erosion of the tube shielding requiring it to be exchanged every few months

  15. Demonstration test of the spent fuel rod cutting process with tube cutter mechanism

    International Nuclear Information System (INIS)

    Lee, Jong Youl; Jung, Jae Hoo; Hong, Dong Hee; Yoon, Ji Sup; Lee, Eun Pyo

    2001-03-01

    In this paper, the verification by computer graphics technology for the spent fuel rod cutting devise which belongs to the spent fuel disassembly processes, the performance tests of the real device, and the demonstration tests with tube cutter mechanism are described. The graphical design system is used throughout the design stages from conceptual design to motion analysis like collision detection. By using this system, the device and the process are optimized. The performance test of the real device and the demonstration test using the tube cutter mechanism in the hot cell are carried out. From these results, the spent fuel rod cutting device is improved based on the considerations of circularity of the rod cross-section, debris generation, and fire risk etc. Also, this device is improved to be operated automatically via remote control system considering later use in closed environment like Hot-cell (radioactive area) and the modulization in the structure of this device makes maintenance easy. The result of the performance test and the demonstration in this report is expected to contribute to the optimization of the pre-treatment processes for the reuse of the spent fuel like DUPIC process and the final disposal

  16. Removing Eddy-current probe wobble noise from steam generator tubes testing using wavelet transform

    International Nuclear Information System (INIS)

    Lopez, Luiz Antonio Negro Martin; Ting, Daniel Kao Sun; Upadhyaya, Belle R.

    2005-01-01

    One of the most import nondestructive evaluation (NDE) applied to steam generator tubes inspection is the electromagnetic Eddy-Current testing (ECT). The signals generated in this NDE, in general, contain many noises which make difficult the interpretation and analysis of ECT signals. One of the noises present in the signals is the probe wobble noise, which is caused by the existing slack between the probe and the tube. In this work, Wavelet Transform (WT) is used in the probe wobble de-noising. WT is a relatively recent mathematical tool, which allows local analysis of non stationary signals such as ECT signals. This is a great advantage of WT when compared with other analysis tools such as Fourier Transform. However, using WT involves wavelets and coefficients selection as well as choosing the number of decomposition level needed. This work presents a probe wobble de-noising method when used in conjunction with the traditional ECT evaluation. Comparative results using several WT applied do Eddy-Current signals are presented in a reliable way, in other words, without loss of inherent defect information. A stainless steel tube, with 2 artificial defects generated by electro-erosion, was inspected by a ZETEC MIZ-17ET ECT equipment. The signals were de-noised through several different WT and the results are presented. The method offer good results and is a promising method because allows for the removal of Eddy-Current signals probe wobble effect without loss of essential signal information. (author)

  17. Standard practice for ultrasonic testing of the Weld Zone of welded pipe and tubing

    CERN Document Server

    American Society for Testing and Materials. Philadelphia

    2010-01-01

    1.1 This practice describes general ultrasonic testing procedures for the detection of discontinuities in the weld and adjacent heat affected zones of welded pipe and tubing by scanning with relative motion between the search unit and pipe or tube. When contact or unfocused immersion search units are employed, this practice is intended for tubular products having specified outside diameters ≥2 in. (≥50 mm) and specified wall thicknesses of 1/8to 11/16 in. (3 to 27 mm). When properly focused immersion search units are employed, this practice may also be applied to material of smaller diameter and thinner wall. Note 1—When contact or unfocused immersion search units are used, precautions should be exercised when examining pipes or tubes near the lower specified limits. Certain combinations of search unit size, frequency, thin–wall thicknesses, and small diameters could cause generation of unwanted sound waves that may produce erroneous examination results. 1.2 All surfaces of material to be examined in ...

  18. Failure analysis of glass-ceramic insulators of shock tested vacuum (neutron) tubes

    International Nuclear Information System (INIS)

    Spears, R.K.

    1980-01-01

    Eight investigative techniques were used to examine the glass-ceramic insulators in vacuum (neutron) tubes. The insulators were extracted from units that had been subjected to low temperature mechanical shock tests. Two of the three units showed reduced neutron output after these tests and an insulator on one of these two was cracked completely through which probably occurred during shock testing. The objective of this study was to determine if any major differences existed between the insulators of these tubes. After eight analyses, it was concluded that no appreciable differences existed. It appeared that cracking of the one glass-ceramic sample was initiated at inner-sleeve interface voids. For this sample, the interface void density was much higher than is presently acceptable. All insulators were made with glass-ceramic having a Na 2 O content of 4.6 wt%. An increased Na 2 O content will cause an increase in the coefficient of expansion and will reduce the residual stress level since the molybdenum has a higher coefficient of thermal expansion than the insulator. Thus, it is believed that a decrease in interface voids and an increase in Na 2 O should aid in reduced cracking of the insulator during these tests

  19. Crack growth of throughwall flaw in Alloy 600 tube during leak testing

    International Nuclear Information System (INIS)

    Bahn, Chi Bum; Majumdar, Saurin

    2015-01-01

    Graphical abstract: - Highlights: • A series of leak testing was conducted at a constant pressure and room temperature. • The time-dependent increase in the leak rate was observed. • The fractography revealed slip offsets and crystallographic facets. • Time-dependent plasticity at the crack tip caused the slip offsets. • Fatigue by jet/structure interaction caused the crystallographic facets. - Abstract: We examined the issue of whether crack growth in a full thickness material can occur in a leaking crack. A series of leak tests was conducted at a room temperature and constant pressure (17.3 MPa) with Alloy 600 tube specimens containing a tight rectangular throughwall axial fatigue crack. To exclude a potential pulsation effect by a high pressure pump, the test water was pressurized by using high pressure nitrogen gas. Fractography showed that crack growth in the full thickness material can occur in the leaking crack by two mechanisms: time-dependent plasticity at the crack tip and fatigue induced by jet/structure interaction. The threshold leak rate at which the jet/structure interaction was triggered was between 1.3 and 3.3 L/min for the specific heat of the Alloy 600 tube tested

  20. Assessment of CCFL model of RELAP5/MOD3 against simple vertical tubes and rod bundle tests

    International Nuclear Information System (INIS)

    Cho, Sung Jae; Arne, Nam Sung; Chung, Bub Dong; Kim, Hho Jung

    1991-01-01

    The CCFL model used in RELAP5/MOD3 version 5m5 has been assessed against simple vertical tubes and rod bundle tests performed at a facility of Korea Atomic Energy Research Institute. The effect of changes in tube diameter and nodalization of tube section were investigated. The roles of interfacial drags on the flooding characteristics are discussed. Difference between the calculation and the experiment are also discussed. A comparison between model assessment results and the test data showed that the calculated value lay well on the experimental flooding curve specified by user, but the pressure jump before onset of flooding was not calculated

  1. Test beam analysis of the first CMS drift tube muon chamber

    CERN Document Server

    Albajar, C; Arce, P; Autermann, C; Bellato, M; Benettoni, M; Benvenuti, Alberto C; Bontenackels, M; Caballero, J; Cavallo, F R; Cerrada, M; Cirio, R; Colino, N; Conti, E; de la Cruz, B; Dal Corso, F; Dallavalle, G M; Fernández, C; Fernández de Troconiz, J; Fouz-Iglesias, M C; García-Abia, P; García-Raboso, A; Gasparini, F; Gasparini, U; Giacomelli, P; Gonella, F; Gulmini, M; Hebbeker, T; Hermann, S; Höpfner, K; Jiménez, I; Josa-Mutuberria, I; Lacaprara, S; Marcellini, S; Mariotti, C; Maron, G; Maselli, S; Meneguzzo, Anna Teresa; Monaco, V; Montanari, A; Montanari, C; Montecassiano, F; Navarria, Francesco Luigi; Odorici, F; Passaseo, M; Pegoraro, M; Peroni, C; Perrotta, A; Puerta, J; Reithler, H; Romero, A; Romero, L; Ronchese, P; Rossi, A; Rovelli, T; Sacchi, R; Sowa, M; Staiano, A; Toniolo, N; Torassa, E; Vaniev, V; Vanini, S; Ventura, Sandro; Villanueva, C; Willmott, C; Zotto, P L; Zumerle, G

    2004-01-01

    In October 2001 the first produced CMS Barrel Drift Tube (DT) Muon Chamber was tested at the CERN Gamma Irradiation Facility (GIF) using a muon beam. A Resistive Plate Chamber (RPC) was attached to the top of the DT chamber, and, for the first time, both detectors were operated coupled together. The performance of the DT chamber was studied for several operating conditions, and for gamma rates similar to the ones expected at LHC. In this paper we present the data analysis; the results are considered fully satisfactory.

  2. Test beam analysis of the first CMS drift tube muon chamber

    International Nuclear Information System (INIS)

    Albajar, C.; Amapane, N.; Arce, P.; Autermann, C.; Bellato, M.; Benettoni, M.; Benvenuti, A.; Bontenackels, M.; Caballero, J.; Cavallo, F.R.; Cerrada, M.; Cirio, R.; Colino, N.; Conti, E.; Cruz, B. de la; Corso, F. dal; Dallavalle, G.M.; Fernandez, C.; Troconiz, J.F. de; Fouz, M.C.; Garcia-Abia, P.; Garcia-Raboso, A.; Gasparini, F.; Gasparini, U.; Giacomelli, P.; Gonella, F.; Gulmini, M.; Hebbeker, T.; Hermann, S.; Hoepfner, K.; Jimenez, I.; Josa, I.; Lacaprara, S.; Marcellini, S.; Mariotti, C.; Maron, G.; Maselli, S.; Meneguzzo, A.T.; Monaco, V.; Montanari, A.; Montanari, C.; Montecassiano, F.; Navarria, F.L.; Odorici, F.; Passaseo, M.; Pegoraro, M.; Peroni, C.; Perrotta, A.; Puerta, J.; Reithler, H.; Romero, A.; Romero, L.; Ronchese, P.; Rossi, A.; Rovelli, T.; Sacchi, R.; Sowa, M.; Staiano, A.; Toniolo, N.; Torassa, E.; Vaniev, V.; Vanini, S.; Ventura, S.; Villanueva, C.; Willmott, C.; Zotto, P.; Zumerle, G.

    2004-01-01

    In October 2001 the first produced CMS Barrel Drift Tube (DT) Muon Chamber was tested at the CERN Gamma Irradiation Facility (GIF) using a muon beam. A Resistive Plate Chamber (RPC) was attached to the top of the DT chamber, and, for the first time, both detectors were operated coupled together. The performance of the DT chamber was studied for several operating conditions, and for gamma rates similar to the ones expected at LHC. In this paper we present the data analysis; the results are considered fully satisfactory

  3. Signal to noise ratio enhancement for Eddy Current testing of steam generator tubes in PWR's

    International Nuclear Information System (INIS)

    Georgel, B.

    1985-01-01

    Noise reduction is a compulsory task when we try to recognize and characterize flaws. The signals we deal with come from Eddy Current testings of steam generator steel tubes. We point out the need for a spectral invariant in digital spectral analysis of 2 components signals. We make clear the pros and cons of classical passband filtering and suggest the use of a new noise cancellation method first discussed by Moriwaki and Tlusty. We generalize this tricky technique and prove it is a very special case of the well-known Wiener filter. In that sense the M-T method is shown to be optimal. 6 refs

  4. Test beam analysis of the first CMS drift tube muon chamber

    Energy Technology Data Exchange (ETDEWEB)

    Albajar, C.; Amapane, N.; Arce, P.; Autermann, C.; Bellato, M.; Benettoni, M.; Benvenuti, A.; Bontenackels, M.; Caballero, J.; Cavallo, F.R.; Cerrada, M.; Cirio, R.; Colino, N.; Conti, E.; Cruz, B. de la; Corso, F. dal; Dallavalle, G.M.; Fernandez, C.; Troconiz, J.F. de E-mail: jorge.troconiz@uam.es; Fouz, M.C.; Garcia-Abia, P.; Garcia-Raboso, A.; Gasparini, F.; Gasparini, U.; Giacomelli, P.; Gonella, F.; Gulmini, M.; Hebbeker, T.; Hermann, S.; Hoepfner, K.; Jimenez, I.; Josa, I.; Lacaprara, S.; Marcellini, S.; Mariotti, C.; Maron, G.; Maselli, S.; Meneguzzo, A.T.; Monaco, V.; Montanari, A.; Montanari, C.; Montecassiano, F.; Navarria, F.L.; Odorici, F.; Passaseo, M.; Pegoraro, M.; Peroni, C.; Perrotta, A.; Puerta, J.; Reithler, H.; Romero, A.; Romero, L.; Ronchese, P.; Rossi, A.; Rovelli, T.; Sacchi, R.; Sowa, M.; Staiano, A.; Toniolo, N.; Torassa, E.; Vaniev, V.; Vanini, S.; Ventura, S.; Villanueva, C.; Willmott, C.; Zotto, P.; Zumerle, G

    2004-06-11

    In October 2001 the first produced CMS Barrel Drift Tube (DT) Muon Chamber was tested at the CERN Gamma Irradiation Facility (GIF) using a muon beam. A Resistive Plate Chamber (RPC) was attached to the top of the DT chamber, and, for the first time, both detectors were operated coupled together. The performance of the DT chamber was studied for several operating conditions, and for gamma rates similar to the ones expected at LHC. In this paper we present the data analysis; the results are considered fully satisfactory.

  5. Sensitive technique for detecting outer defect on tube with remote field eddy current testing

    International Nuclear Information System (INIS)

    Kobayashi, Noriyasu; Nagai, Satoshi; Ochiai, Makoto; Jimbo, Noboru; Komai, Masafumi

    2008-01-01

    In the remote field eddy current testing, we proposed the method of enhancing the magnetic flux density in the vicinity of an exciter coil by controlling the magnetic flux direction for increasing the sensitivity of detecting outer defects on a tube and used the flux guide made of a magnetic material for the method. The optimum structural shape of the flux guide was designed by the magnetic field analysis. On the experiment with the application of the flux guide, the magnetic flux density increased by 59% and the artificial defect detection signal became clear. We confirmed the proposed method was effective in a high sensitivity. (author)

  6. Limits to the Recognizability of Flaws in Non-Destructive Testing Steam-Generator Tubes for Nuclear-Power Plants

    International Nuclear Information System (INIS)

    Kuhlmann, A.; Adamsky, F.-J.

    1965-01-01

    In the Federal Republic of Germany there are nuclear reactors under construction with steam generators inside the reactor pressure-vessel. As a result design repairs of steam- generator tubes are very difficult and cause large shut-down times of the nuclear-power plant. It is known that numerous troubles in operating conventional power plants are results of steam-generator tube damages. Because of the high total costs of these reactors it. is necessary to construct the steam generators especially in such a manner that the load factor of the power plant is as high as possible. The Technischer Überwachungs-Verein Rheinland was charged to supervise and to test fabrication and construction of the steam generators to see that this part of the plant was as free of defects as possible. The experience gained during this work is of interest for manufacture and construction of steam generators for nuclear-power plants in general. This paper deals with the efficiency limits of non-destructive testing steam-generator tubes. The following tests performed will be discussed in detail: (a) Automatic ultrasonic testing of the straight tubes in the production facility; (b) Combined ultrasonic and radiographic testing of the bent tubes and tube weldings; (c) Other non-destructive tests. (author) [fr

  7. Influence of the centrifuge time of primary plasma tubes on routine coagulation testing.

    Science.gov (United States)

    Lippi, Giuseppe; Salvagno, Gian Luca; Montagnana, Martina; Manzato, Franco; Guidi, Gian Cesare

    2007-07-01

    Preparation of blood specimens is a major bottleneck in the laboratory throughput. Reliable strategies for reducing the time required for specimen processing without affecting quality should be acknowledged, especially for laboratories performing stat analyses. The present investigation was planned to establish a minimal suitable centrifuge time for primary samples collected for routine coagulation testing. Five sequential primary vacuum tubes containing 0.109 mol/l buffered trisodium citrate were collected from 10 volunteers and were immediately centrifuged on a conventional centrifuge at 1500 x g, at room temperature for 1, 2, 5, 10 and 15 min, respectively. Hematological and routine coagulation testing, including prothrombin time, activated partial thromboplastin time and fibrinogen, were performed. The centrifugation time was inversely associated with residual blood cell elements in plasma, especially platelets. Statistically significant variations from the reference 15-min centrifuge specimens were observed for fibrinogen in samples centrifuged for 5 min at most and for the activated partial thromboplastin time in samples centrifuged for 2 min at most. Meaningful biases related to the desirable bias were observed for fibrinogen in samples centrifuged for 2 min at most, and for the activated partial thromboplastin time in samples centrifuged for 1 min at most. According to our experimental conditions, a 5-10 min centrifuge time at 1500 x g may be suitable for primary tubes collected for routine coagulation testing.

  8. Code Assessment of SPACE 2.19 using LSTF Steam Generator Tube Rupture Test

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Minhee; Kim, Seyun [KHNP CRI, Daejeon (Korea, Republic of)

    2016-10-15

    The SPACE is a best estimated two-phase three-field thermal-hydraulic analysis code used to analyze the safety and performance of pressurized water reactors. As a result of the development, the 2.19 version of the code was released through the successive various verification and validation works. The present work is on the line of expanding the work by Kim et al. In this study, results produced by the SPACE 2.19 code were compared with the experimental data from JAERI's LSTF Test Run LSTF SB-SG-06 experiment simulating a Steam Generator Tube Rupture (SGTR) transient. In order to identify the predictability of SPACE 2.19, the LSTF steam generator tube rupture test was simulated. To evaluate the computed results, LSTF SB-SG-06 test data simulating the SGTR and the RELAP5/ MOD3.1 are used. The calculation results indicate that the SPACE 2.19 code predicted well the sequence of events and the major phenomena during the transient, such as the asymmetric loop behavior, reactor coolant system cooldown and heat transfer by natural circulation, the primary and secondary system depressurization by the pressurizer auxiliary spray and the steam dump using the intact loop steam generator relief valve.

  9. Semantic test of a technology management model in family business

    Directory of Open Access Journals (Sweden)

    Guillermo Jesús Larios

    2017-10-01

    Full Text Available This paper assembles family business conceptions from the innovation and technology management perspective, and tests them in the case of a Mexican sugarcane producer. Literature indicates that non-financial objectives, risk aversion and strong controls negatively influence family firms’ innovation outcomes. Based on semantic network analysis, we collected transversal information on the firm’s technology activities, innovation values and organizational flows, which allowed for the identification of an organizational management profile that shapes an innovation style. Although we acknowledge literature consistency in aspects such as family direct influence and control, or the importance of STI partnerships and external knowledge, our findings didn’t identify any concerns about losing control in parts of the family business. This research contributes to the understanding of technology management and organizational elements in an emerging economy’s family firm from a relational perspective. Implications for theory endorsement and characterization of family business innovation and technology management in developing countries are discussed.

  10. QuantiFERON–TB Gold In-Tube test performance in Denmark

    DEFF Research Database (Denmark)

    Hermansen, Thomas; Lillebaek, Troels; Hansen, Ann-Brit E

    2014-01-01

    BACKGROUND: Little is known about the QuantiFERON-TB Gold In-Tube Test (QFT) in extreme age groups. The test performance has been reported to be impaired in children and elderly, but reports are diverging. The aim of this study was to evaluate QFT performance in patients with and without......, the overall QFT performance was good. The sensitivity in children (≥ 1) was high although few children were included, whereas sensitivity declined with increasing age. Indeterminate rates were higher in infants and elderly. In contrast to current guidelines, our data suggest that the QFT performs well...... in children ≥ 1 years in low endemic regions but that the test should be used with care among the elderly....

  11. Application of automatic inspection system to nondestructive test of heat transfer tubes of primary pressurized water cooler in the high temperature engineering test reactor. Joint research

    International Nuclear Information System (INIS)

    Takeda, Takeshi; Furusawa, Takayuki

    2001-07-01

    Heat transfer tubes of a primary pressurized water cooled (PPWC) in the high temperature engineering test reactor (HTTR) form the reactor pressure boundary of the primary coolant, therefore are important from the viewpoint of safety. To establish inspection techniques for the heat transfer tubes of the PPWC, an automatic inspection system was developed. The system employs a bobbin coil probe, a rotating probe for eddy current testing (ECT) and a rotating probe for ultrasonic testing (UT). Nondestructive test of a half of the heat transfer tubes of the PPWC was carried out by the automatic inspection system during reactor shutdown period of the HTTR (about 55% in the maximum reactor power in this paper). The nondestructive test results showed that the maximum signal-to-noise ratio was 1.8 in ECT. Pattern and phase of Lissajous wave, which were obtained for the heat transfer tube of the PPWC, were different from those obtained for the artificially defected tube. In UT echo amplitude of the PPWC tubes inspected was lower than 20% of distance-amplitude calibration curve. Thus, it was confirmed that there was no defect in depth, which was more than the detecting standard of the probes, on the outer surface of the heat transfer tubes of the PPWC inspected. (author)

  12. Development of a sealing process of capsules for surveillance test tubes of the vessel in nuclear power plants; Desarrollo de proceso de sellado de capsulas para probetas de vigilancia de la vasija en nucleoelectricas

    Energy Technology Data Exchange (ETDEWEB)

    Romero C, J.; Fernandez T, F.; Perez R, N.; Rocamontes A, M.; Garcia R, R. [ININ, Km 36.5 Carretera Mexico-Toluca, 52750 La Marquesa, Estado de Mexico (Mexico)

    2007-07-01

    The surveillance capsule is composed by the support, three capsules for impact test tubes, five capsules for tension test tubes and one porta dosemeters. The capsules for test tubes are of two types: rectangular capsule for Charpy test tubes and cylindrical capsule for tension test tubes. This work describes the development of the welding system to seal the capsules for test tubes that should contain helium of ultra high purity to a pressure of 1 atmosphere. (Author)

  13. Non-destructive testing of high pressure fibre reinforced composites tubes by computed tomography

    Energy Technology Data Exchange (ETDEWEB)

    Klimek, L. [Qualitaetszentrum Dortmund (Germany); Monstadt, H.; Boedecker, T. [EFMT, Bochum (Germany)

    1995-12-31

    For new applications of fibre reinforced composites, new non-destructive testing methods are required which on the one hand can be used as a quality testing method and on the other hand as an in-service inspection method during the life of a product. Special attention should be paid to the defect sensitivity and to a detailed classification of visible defects. Defining a detectable standard, comparable investigations were carried out using the Ultra Fast Scanner which is located at the Entwicklungs- und Forschungszentrum fuer Mikrotherapie gGmbH (EFMT) and the industrial scanner of the Qualitaetszentrum Dortmund GmbH u. Co. KG (QZ-DO). The investigation object is a high pressure tube which is made up of three different diameter structures. There can be distinguished between three types of tube layers. Digital image processing has been used to get more information form measured data. We developed two different types of digital image filters: A SIGMA and a Contrast Sensitive Weights (CSW) image filter and made a comparative study. (orig./RHM)

  14. A Simple Test Tube-Based ELISA Experiment for the High-School Classroom*

    Science.gov (United States)

    Brokaw, Ann; Cobb, Brian A.

    2010-01-01

    Immunology is gaining prominence both in the media as well as on the Advanced Placement (AP) exam in Biology. One of the challenges of teaching modern biological topics such as immunology and biochemistry in the high-school setting is the increased reliance on expensive technology in the research world. To begin to bridge this widening gap, we devised an experiment using a novel macroscale enzyme-linked immunosorbent assay that is suitable for AP-level high-school biology classrooms as well as entry-level collegiate laboratories. This novel method does not require a plate reader for data analysis, but instead relies on more common and inexpensive equipment such as a clinical test tube centrifuge and a simple test tube spectrophotometer. The experimental plan focuses on students measuring antibody concentrations in “unknown” samples and includes the collection and analysis of a standard curve using reagents prepared by the instructor. Students will be introduced to enzyme action, quantitative laboratory technique, antibodies, and the immune system, with the overall goal being to explore and highlight the inherent connections within the fields of biochemistry and immunology. PMID:20689684

  15. Cumulative damage fatigue tests on nuclear reactor Zircaloy-2 fuel tubes at room temperature and 3000C

    International Nuclear Information System (INIS)

    Pandarinathan, P.R.; Vasudevan, P.

    1980-01-01

    Cumulative damage fatigue tests were conducted on the Zircaloy-2 fuel tubes at room temperature and 300 0 C on the modified Moore type, four-point-loaded, deflection-controlled, rotating bending fatigue testing machine. The cumulative cycle ratio at fracture for the Zircaloy-2 fuel tubes was found to depend on the sequence of loading, stress history, number of cycles of application of the pre-stress and the test temperature. A Hi-Lo type fatigue loading was found to be very much damaging at room temperature and this feature was not observed in the tests at 300 0 C. Results indicate significant differences in damage interaction and damage propagation under cumulative damage tests at room temperature and at 300 0 C. Block-loading fatigue tests are suggested as the best method to determine the life-time of Zircaloy-2 fuel tubes under random fatigue loading during their service in the reactor. (orig.)

  16. Fever in the test tube--towards a human(e) pyrogen test.

    Science.gov (United States)

    Schindler, Stephanie; Fennrich, Stefan; Crameri, Reto; Jungi, Thomas W; Montag, Thomas; Hartung, Thomas

    2007-01-01

    The human whole blood IL-1 test exploits the reaction of monocytes/macrophages for the detection of pyrogens: human whole blood taken from healthy volunteers is incubated in the presence of the test sample in any form, be it a solution, a powder or even solid material. Pyrogenic contaminations initiate the release of the "endogenous pyrogen" Interleukin-1beta determined by ELISA after incubation. In order to understand any differences between the pyrogenic activity in this test and the existing live rabbit test (species differences versus aberrant response of the particular blood sample), the rabbit whole blood test was developed. This approach could also help to avoid the use of putatively infectious human blood for pyrogen testing in vitro.

  17. Design and fabrication of hafnium tube to control the power of the irradiation test fuel in HANARO

    Energy Technology Data Exchange (ETDEWEB)

    Kim, D. H.; Lee, C. B.; Kim, Y. M.; Yang, Y. S.; Jung, Y. H

    2003-05-01

    For the irradiation test at HANARO, non-instrumentation capsule was manufactured and hafnium tube was used to control LHGR of HANARO. Hafnium tube can control the irradiation condition of HANARO similar to that of commercial reactor. Hafnium tube thickness was determined by the LHGR calculated at OR-4 irradiation hole to be installed the non-instrumented capsule. To fabricate the hafnium tube with hafnium plate, the fabrication method was determined by using the hafnium mechanical properties. And the tensile strength of hafnium was confirmed by tensile test. This report is confirmed the LHGR control at the OR-4 and the Hafnium fabrication for in used which the AFPCAP non-instrumented irradiation capsule.

  18. Family-based clusters of cognitive test performance in familial schizophrenia

    Directory of Open Access Journals (Sweden)

    Partonen Timo

    2004-07-01

    Full Text Available Abstract Background Cognitive traits derived from neuropsychological test data are considered to be potential endophenotypes of schizophrenia. Previously, these traits have been found to form a valid basis for clustering samples of schizophrenia patients into homogeneous subgroups. We set out to identify such clusters, but apart from previous studies, we included both schizophrenia patients and family members into the cluster analysis. The aim of the study was to detect family clusters with similar cognitive test performance. Methods Test scores from 54 randomly selected families comprising at least two siblings with schizophrenia spectrum disorders, and at least two unaffected family members were included in a complete-linkage cluster analysis with interactive data visualization. Results A well-performing, an impaired, and an intermediate family cluster emerged from the analysis. While the neuropsychological test scores differed significantly between the clusters, only minor differences were observed in the clinical variables. Conclusions The visually aided clustering algorithm was successful in identifying family clusters comprising both schizophrenia patients and their relatives. The present classification method may serve as a basis for selecting phenotypically more homogeneous groups of families in subsequent genetic analyses.

  19. Computer control in nondestructive testing illustrated by an automatic ultrasonic tube inspection system

    International Nuclear Information System (INIS)

    Gundtoft, H.E.; Nielsen, N.

    1976-06-01

    In Risoe's automatic tube inspection system, data (more than half a million per tube) from ultrasonic dimension measurements and defect inspections are fed into a computer that simultaneously calculates and evaluates the results. (author)

  20. Isothermal Amplification for MicroRNA Detection: From the Test Tube to the Cell.

    Science.gov (United States)

    Deng, Ruijie; Zhang, Kaixiang; Li, Jinghong

    2017-04-18

    MicroRNAs (miRNAs) are a class of small noncoding RNAs that act as pivotal post-transcriptional regulators of gene expression, thus involving in many fundamental cellular processes such as cell proliferation, migration, and canceration. The detection of miRNAs has attracted significant interest, as abnormal miRNA expression is identified to contribute to serious human diseases such as cancers. Particularly, miRNAs in peripheral blood have recently been recognized as important biomarkers potential for liquid biopsy. Furthermore, as miRNAs are expressed heterogeneously in different cells, investigations into single-cell miRNA expression will be of great value for resolving miRNA-mediated regulatory circuits and the complexity and heterogeneity of miRNA-related diseases. Thus, the development of miRNA detection methods, especially for complex clinic samples and single cells is in great demand. In this Account, we will present recent progress in the design and application of isothermal amplification enabling miRNA detection transition from the test tube to the clinical sample and single cell, which will significantly advance our knowledge of miRNA functions and disease associations, as well as its translation in clinical diagnostics. miRNAs present a huge challenge in detection because of their extremely short length (∼22 nucleotides) and sequence homology (even with only single-nucleotide variation). The conventional golden method for nucleic acid detection, quantitative PCR (qPCR), is not amenable to directly detecting short RNAs and hardly enables distinguishing between miRNA family members with very similar sequences. Alternatively, isothermal amplification has emerged as a powerful method for quantification of nucleic acids and attracts broad interest for utilization in developing miRNA assays. Compared to PCR, isothermal amplification can be performed without precise control of temperature cycling and is well fit for detecting short RNA or DNA. We and other

  1. GERDA test facility for pressurized water reactors with straight tube steam generators

    International Nuclear Information System (INIS)

    Ahrens, G.; Haury, G.; Lahner, K.; Schatz, A.

    1983-01-01

    A number of large-scale experimental facilities have been constructed and operate in order to experiment on the thermodynamic and thermohydraulic behaviour of nuclear facilities in case of LOCA. Most of them were designed for ''large leak'' accidents, but as ''small leak'' accidents became the focus of interest, such experiments were also carried out. Experiments carried out with this arrangement for PWR-type reactors with straight-tube steam generators are only partially evaluable. BBR and B and W therefore cooperated in the construction of the test facility GERDA, designed for testing reactors of BBR design. It supplied relevant experimental results for the nuclear power plant at Muelheim-Kaerlich. (orig.) [de

  2. Ferrocyanide safety program: Final report on adiabatic calorimetry and tube propagation tests with synthetic ferrocyanide materials

    International Nuclear Information System (INIS)

    Fauske, H.F.; Meacham, J.E.; Cash, R.J.

    1995-01-01

    Based on Fauske and Associates, Inc. Reactive System Screening Tool tests, the onset or initiation temperature for a ferrocyanide-nitrate propagating reaction is about 250 degrees Celcius. This is at about 200 degrees Celcius higher than current waste temperatures in the highest temperature ferrocyanide tanks. Furthermore, for current ambient waste temperatures, the tube propagation tests show that a ferrocyanide concentration of 15.5 wt% or more is required to sustain a propagation reaction in the complete absence of free water. Ignoring the presence of free water, this finding rules out propagating reactions for all the Hanford flowsheet materials with the exception of the ferrocyanide waste produced by the original In Farm flowsheet

  3. A standardized procedure for eddy-current testing of stainless steel, thin-walled nuclear fuel element cladding tubes

    International Nuclear Information System (INIS)

    Barat, P.; Raj, B.; Bhattacharya, D.K.

    1982-01-01

    Thin-walled nuclear fuel cladding tubes made of AISI 316 stainless steel have been examined by eddy-current testing. Standardization of the procedures has required investigations on optimizing the test frequency, finding a method to locate a defect with respect to the probe reference end, and the use of standard defects and sequential metallography of natural defects detected by eddy-current testing, to understand the influence of the nature of defects on the impedance output signals. Test frequency and method of locating the defect were optimized by the use of standard defects made by machining in reference cladding tubes. Subsequent metallography of natural defects detected by eddy-current testing revealed mainly clusters of inclusions but also other types of defects. The effect of the distribution of inclusions along the length of the tube on the impedance output is discussed. (author)

  4. Standardized procedure for eddy-current testing of stainless steel, thin-walled nuclear fuel element cladding tubes

    Energy Technology Data Exchange (ETDEWEB)

    Barat, P; Raj, B; Bhattacharya, D K [Reactor Research Centre, Kalpakkam (India)

    1982-10-01

    Thin-walled nuclear fuel cladding tubes made of AISI 316 stainless steel have been examined by eddy-current testing. Standardization of the procedures has required investigations on optimizing the test frequency, finding a method to locate a defect with respect to the probe reference end, and the use of standard defects and sequential metallography of natural defects detected by eddy-current testing, to understand the influence of the nature of defects on the impedance output signals. Test frequency and method of locating the defect were optimized by the use of standard defects made by machining in reference cladding tubes. Subsequent metallography of natural defects detected by eddy-current testing revealed mainly clusters of inclusions but also other types of defects. The effect of the distribution of inclusions along the length of the tube on the impedance output is discussed.

  5. Development and validation of a simulation tool dedicated to eddy current non destructive testing of tubes

    International Nuclear Information System (INIS)

    Reboud, Ch.

    2006-09-01

    Eddy current testing (ECT) technique is widely used in industrial fields such as iron and steel industry. Dedicated simulation tools provide a great assistance for the optimisation of ECT processes. CEA and the Vallourec Research Center have collaborated in order to develop a simulation tool of ECT of tubes. The volume integral method has been chosen for the resolution of Maxwell equations in a stratified medium, in order to get accurate results with a computation time short enough to carry out optimisation or inversion procedures. A fast model has been developed for the simulation of ECT of non magnetic tubes using specific external probes. New flaw geometries have been modelled: holes and notches with flat bottom. Validations of the developments, which have been integrated to the CIVA platform, have been carried out using experimental data recorded in laboratory conditions and in. industrial conditions, successively. The integral equations derived are solved using the Galerkin variant of the method of moments with pulse functions as projection functions. In order to overcome some memory limitations, other projection functions have been considered. A new discretization scheme based on non-uniform B-Splines of degree 1 or 2 has been implemented, which constitutes an original contribution to the existing literature. The decrease of the mesh size needed to get a given accuracy on the result may lead to the simulation of more complex ECT configurations. (author)

  6. Socioeconomic status and parenting in ethnic minority families: testing a minority family stress model.

    Science.gov (United States)

    Emmen, Rosanneke A G; Malda, Maike; Mesman, Judi; van Ijzendoorn, Marinus H; Prevoo, Mariëlle J L; Yeniad, Nihal

    2013-12-01

    According to the family stress model (Conger & Donnellan, 2007), low socioeconomic status (SES) predicts less-than-optimal parenting through family stress. Minority families generally come from lower SES backgrounds than majority families, and may experience additional stressors associated with their minority status, such as acculturation stress. The primary goal of this study was to test a minority family stress model with a general family stress pathway, as well as a pathway specific to ethnic minority families. The sample consisted of 107 Turkish-Dutch mothers and their 5- to 6-year-old children, and positive parenting was observed during a 7-min problem-solving task. In addition, mothers reported their daily hassles, psychological distress, and acculturation stress. The relation between SES and positive parenting was partially mediated by both general maternal psychological stress and maternal acculturation stress. Our study contributes to the argument that stressors specific to minority status should be considered in addition to more general demographic and family stressors in understanding parenting behavior in ethnic minority families.

  7. Transgenic Mouse Models Transferred into the Test Tube: New Perspectives for Developmental Toxicity Testing In Vitro?

    Science.gov (United States)

    Kugler, Josephine; Luch, Andreas; Oelgeschläger, Michael

    2016-10-01

    Despite our increasing understanding of molecular mechanisms controlling embryogenesis, the identification and characterization of teratogenic substances still heavily relies on animal testing. Embryonic development depends on cell-autonomous and non-autonomous processes including spatiotemporally regulated extracellular signaling activities. These have been elucidated in transgenic mouse models harboring easily detectable reporter genes under the control of evolutionarily conserved signaling cascades. We propose combining these transgenic mouse models and cells derived thereof with existing alternative toxicological testing strategies. This would enable the plausibility of in vitro data to be verified in light of in vivo data and, ultimately, facilitate regulatory acceptance of in vitro test methods. Copyright © 2016 Elsevier Ltd. All rights reserved.

  8. Silencing of the pollen-specific gene NTP303 and its family members in tobacco affects in vivo pollen tube growth and results in male sterile plants.

    Science.gov (United States)

    de Groot, Peter; Weterings, Koen; de Been, Mark; Wittink, Floyd; Hulzink, Raymond; Custers, Jan; van Herpen, Marinus; Wullems, George

    2004-07-01

    In seed plants, successful fertilization requires correct regulation of pollen tube growth. At germination and during growth, the pollen tube interacts with tissues from the pistil while the pollen tube extends via tip growth. Despite the fact that much research has been devoted to the mechanisms regulating pollen tube growth, many aspects are currently unknown. Previously, we have isolated a pollen-specific gene from tobacco--NTP303--that probably functions during pollen tube growth. NTP303 is part of a family of five members. Its expression is regulated both at the transcriptional and at the translational level. While NTP303 transcripts accumulate to high levels between early bi-cellular and mature pollen stages, NTP303 protein is hardly detectable until germination and pollen tube growth. In order to elucidate the role and function of NTP303 in the pollen tube, we studied the effect of NTP303 gene silencing on pollen function. Therefore, we have transformed tobacco plants with NTP303 co-suppression and anti-sense gene constructs. In these plants, the kanamycin resistance trait--which was linked to the NTP303-silencing gene--was not transmitted through the male gametophyte. This indicated that lowering the transcript level of NTP303 and/or its family members interferes with pollen function. Because we could not find a readily distinguishable phenotype in pollen from the hemizygous anti-sense and co-suppression plants, we rescued the defective pollen to produce doubled haploid plants that were homozygous for the NTP303 anti-sense gene. We found that in pollen from these plants the transcript levels of all NTP303 family members were reduced. Although pollen and pollen tubes from these plants appeared completely normal in vitro, the pollen tubes showed slower growth rates in vivo and arrested in the style before they reached the ovary, so that fertilization failed. These data demonstrate that NTP303 and its family members are essential for normal pollen tube growth

  9. Radiographic testing methods for welds of thin titanium plates and thin wall tubes

    International Nuclear Information System (INIS)

    1984-01-01

    This standard stipulates the testing method by X-ray radiography for the welded parts of titanium plates and titanium tubes with thickness not exceeding 8 mm. The other items than those stipulated here shall be in accordance with JIS Z 3107-1973 ''Testing method by radiography for the welded part of titanium and method of grade classification of radiographs''. As the photographing method of radiographs, the performance of the equipment and materials for testing, the direction of X-ray irradiation, the thickness of parent materials and welds, the use of penetrameters, the arrangement for photographing, the requirement for radiographs and the observation of radiographs are specified. The X-ray apparatuses, photo-sensitive materials and the tools for photographing and observation must be such that the radiographs clearly showing the defects in the welds being tested can be taken or observed. The JIS Z 3107 is insufficient for the test of thin materials like titanium, therefore, this standard was set down. As the thickness of welds, the thickness of parent materials was taken. In this standard, the titanium penetrameters were adopted because they can be made and they conform to practical state. If magnified photographing is carried out with microfocus X-ray apparatuses, precise photographing can be made. (Kako, I.)

  10. Improvement of ISI techniques by multi-frequency eddy current testing method for steam generator tube in PWR plant

    International Nuclear Information System (INIS)

    Endo, Takashi; Kamimura, Takeo; Nishihara, Masatoshi; Araki, Yasuo; Fukui, Shigetaka.

    1982-05-01

    Eddy current flaw detection techniques are applied to the in-service inspection (ISI) of steam generator tubes in pressurized water reactors (PWR) plant. To improve the reliability and operating efficiency of the plants, efforts are being made to develop eddy current testing methods of various kinds. Multi-frequency eddy current testing method, one of new method, has recently been applied to actual heat exchanger tubes, contributing to the improvement of the detectability and signal evaluation of the ISI. The outline of multi-frequency eddy current testing method and its effects on the improvement of flaw detecting and signal evaluation accuracy are described. (author)

  11. Basophil activation test: food challenge in a test tube or specialist research tool?

    Science.gov (United States)

    Santos, Alexandra F; Lack, Gideon

    2016-01-01

    Oral food challenge (OFC) is the gold-standard to diagnose food allergy; however, it is a labour and resource-intensive procedure with the risk of causing an acute allergic reaction, which is potentially severe. Therefore, OFC are reserved for cases where the clinical history and the results of skin prick test and/or specific IgE do not confirm or exclude the diagnosis of food allergy. This is a significant proportion of patients seen in Allergy clinics and results in a high demand for OFC. The basophil activation test (BAT) has emerged as a new diagnostic test for food allergy. With high diagnostic accuracy, it can be particularly helpful in the cases where skin prick test and specific IgE are equivocal and may allow reducing the need for OFC. BAT has high specificity, which confers a high degree of certainty in confirming the diagnosis of food allergy and allows deferring the performance of OFC in patients with a positive BAT. The diagnostic utility of BAT is allergen-specific and needs to be validated for different allergens and in specific patient populations. Standardisation of the laboratory methodology and of the data analyses would help to enable a wider clinical application of BAT.

  12. Audiometric Testing Guideline Adherence in Children Undergoing Tympanostomy Tubes: A Population-Based Study.

    Science.gov (United States)

    Beyea, Jason A; Rosen, Emily; Stephens, Trina; Nguyen, Paul; Hall, Stephen F

    2018-02-01

    Objective Tympanostomy tube (TT) insertion is the most common ambulatory surgery performed on children. American Academy of Otolaryngology-Head and Neck Surgery Founda-tion (AAO-HNSF) Clinical Practice Guidelines (CPGs) recommend hearing testing for all pediatric TT candidates. The aim of this study was to assess audiometric testing in this population. Study Design Retrospective population-based cohort study. Setting All hospitals in the Canadian province of Ontario. Subjects and Methods All patients 12 years of age and younger who underwent at least 1 TT procedure between January 1993 and June 2016. The primary outcomes were the percentage of patients who underwent a hearing test within 1 year before and/or 1 year after surgery. Results A total of 316,599 bilateral TT procedures were performed during the study period (1993 to 2016). Presurgical hearing tests increased from 55.7% to 74.9%, and postsurgical hearing tests increased from 42.2% to 68.9%. Younger surgeons demonstrated a greater adherence to the CPGs (relative risk [RR], 1.22; 95% CI, 1.08-1.38; P = .001). Remarkably, there was not a spike in preoperative hearing tests following the introduction of the CPGs in 2013 (RR, 1.12; 95% CI, 0.85-1.47; P = .432). Presurgical hearing testing ranged from 26.1% to 83.5% across health regions. Conclusion In this cohort of children who underwent TT placement, the trends of preoperative and postoperative audiometric testing are increasing but are still lower than recommended by the CPGs, despite a tripling of practicing audiologists. This study describes the current state of testing in Ontario and highlights issues of access to audiology services, possible parent preferences, and the importance of ongoing continuing medical education for all health care practitioners.

  13. Structural integrity testing of glass-ceramic/molybdenum vacuum tube frames

    International Nuclear Information System (INIS)

    Spears, R.K.

    1980-01-01

    In this study, vacuum tube subassemblies made of glass-ceramic insulators sealed to inner and outer molybdenum frames were loaded in compression to failure with a tensile test machine. Several factors were varied in processing these subassemblies. These factors included etching and nonetching of molybdenum piece parts, annealing and nonannealing of subassemblies, and vapor and non-vapor honing of insulators after sealing. After failure, the subassemblies were examined for fracture patterns. In most cases, fracture started at points near the lower portion of the inner sleeve-insulator interface. More load was carried by subassemblies having molybdenum piece parts that were acid etched. No difference appeared between the strength of subassemblies having annealed and nonannealed glass-ceramic insulators. Parts with vapor-honed insulators failed at substantially lower loads

  14. Development of intelligent Eddy Current Testing (ECT) system for PWR steam generator tube inspection

    International Nuclear Information System (INIS)

    Kawata, K.; Kawase, N.; Kurokawa, M.; Asada, Y.

    2005-01-01

    The intelligent ECT system was developed for the inspection of heat transfer tubes of the steam generator of the PWR plant. It consists of intelligent probe, data acquisition unit and data analysis system. The probe combines 24 channels inclined lay out drive coils and thin film pick-up coils with built-in electric circuits to provide high inspection capability equivalent to rotating coil ECT and high-speed inspection equivalent to conventional bobbin coil ECT. The advanced data analysis system that has filtering and automatic analysis functions is also developed to enable fast and precise analysis of large volume inspection data. The system was qualified by confirmation tests in FY 2003 to show thinned thickness sizing accuracy within ± 5%. (T. Tanaka)

  15. Time-lapse cinematography of the capillary tube cell migration inhibition test.

    Science.gov (United States)

    Bray, M A

    1980-01-01

    The kinetics of human and guinea pig cell migration inhibition have been studied using time-lapse cinematography of cells migrating from capillary tubes. Guinea pig and human cells exhibit markedly different kinetics in the absence of inhibitors. Specific antigen causes a dose-related inhibition of migration for up to 60 h using guinea pig cells and a peak of inhibition after 18 h using the human leucocyte system. The timing of measurement of maximum activity more critical for the latter test. The kinetics of lymphokine generation have been examined and the migration inhibitory activity of the plant mitogen (PHA), a Kurloff cell product and a continuous cell line supernatant have been compared with the inhibitory profiles of lymphokine preparations and specific antigen.

  16. Darwin's concepts in a test tube: parallels between organismal and in vitro evolution.

    Science.gov (United States)

    Díaz Arenas, Carolina; Lehman, Niles

    2009-02-01

    The evolutionary process as imagined by Darwin 150 years ago is evident not only in nature but also in the manner in which naked nucleic acids and proteins experience the "survival of the fittest" in the test tube during in vitro evolution. This review highlights some of the most apparent evolutionary patterns, such as directional selection, purifying selection, disruptive selection, and iterative evolution (recurrence), and draws parallels between what happens in the wild with whole organisms and what happens in the lab with molecules. Advances in molecular selection techniques, particularly with catalytic RNAs and DNAs, have accelerated in the last 20 years to the point where soon any sort of complex differential hereditary event that one can ascribe to natural populations will be observable in molecular populations, and exploitation of these events can even lead to practical applications in some cases.

  17. [Genetic counseling and testing for families with Alzheimer's disease].

    Science.gov (United States)

    Kowalska, Anna

    2004-01-01

    With the identification of the genes responsible for autosomal dominant early-onset familial Alzheimer's disease (FAD genes), there is a considerable interest in the application of this genetic information in medical practice through genetic testing and counseling. Pathogenic mutations in the PSEN1 and PSEN2 genes encoding presenilin-1 and -2, and the APP gene encoding amyloid b precursor protein, account for 18-50% of familial EOAD cases with autosomal dominant pattern of inheritance. A clinical algorithm of genetic testing and counseling proposed for families with AD has been presented here. A screening for mutations in the APP, PSEN1, and PSEN2 genes is available to individuals with AD symptoms and at-risk children or siblings of patients with early-onset disease determined by a known mutation. In an early-onset family, a known mutation in an affected patient puts the siblings and children at a 50% risk of inheriting the same mutation. The goal of genetic testing is to identify at-risk individuals in order to facilitate early and effective treatments in the symptomatic person based on an individual's genotype and strategies to delay the onset of disease in the presymptomatic mutation carriers. However, there are several arguments against the use of genetic testing both presymptomatically (unpredictable psychological consequences of information about a genetic defect for family members) and as a diagnostic tool for the differential diagnosis of dementia in general practice (a risk of errors in an interpretation of mutation penetrance and its secondary effects on family members, especially for novel mutations; the possibility of coexistence of another form of dementia at the presence of a mutation). Currently, APOE genotyping for presymptomatic individuals with a family history of late-onset disease is not recommended. The APOE4 allele may only confer greater risk for disease, but its presence is not conclusive for the development of AD.

  18. Comparison of manual mycobacteria growth indicator tube and epsilometer test with agar proportion method for susceptibility testing of Mycobacterium tuberculosis

    Directory of Open Access Journals (Sweden)

    N Karabulut

    2014-01-01

    Full Text Available Background and Objectives: Antimycobacterial susceptibility tests take weeks, and delayed therapy can lead to spread of Mycobacterium tuberculosis. Therefore, rapid, accurate and cost-effective methods are required for proper therapy selection. In this study, the Mycobacteria growth indicator tube (MGIT and epsilometer test (Etest methods were compared to the agar proportion method for susceptibility testing of Mycobacterium tuberculosis. Materials and Methods: The susceptibility tests against isoniazid (INH, rifampin (RIF, streptomycin (STM and ethambutol (ETM of 51 M. tuberculosis complex isolates were analyzed by the MGIT, Etest and agar proportion methods. Results: The concordance between MGIT/Etest and agar proportion methods was 98% for INH and 100% for RIF, STM, ETM. There were not statistically significant differences in results of the susceptibility tests between MGIT/Etest and the reference agar proportion method. Conclusion: The results have shown that MGIT and Etest methods can be used instead of the agar proportion method, because these two methods are more rapid and easier than the agar proportion method.

  19. Expert system for eddy current signal analysis: non destructive testing of steam generator tubings

    International Nuclear Information System (INIS)

    Benoist, B.

    1991-01-01

    Automatic analysis, by computer, of defect signals in steam generator tubes, based on Eddy current multifrequency technique, is must often inefficient due to pilgrim noise. The first step is to use a method that allows us to eleminate the noise: the adaptative interpolation. Thanks to this method, which ensures reliable data on each channel, the analysis can be realised by taking into account the data corresponding to each basic or mixed channel. By correlating these diverse data, we can class the signals according to two types of defects: single defects (symmetrical), multiple defects (several in the same place). The second step is to use an expert system which allows a reliable diagnosis for whatever family the defect belongs to. According to this classification, analysis is continued and results in the characterization of the defect. The expert system has already been developed with the general purpose application expert system shell SUPER, which is briefly described. The knowledge base (SOCRATE) and the specific tools developed for this application are thoroughly described. The first results obtained with signals corresponding to real defects, that have been recorded in different places, are presented and discussed. The expert system is revealed efficient in all the studied cases, even with signals obtained in very noisy environments [fr

  20. Verification of neutron pad and 17 x 7 guide tube designs by preoperational tests on the Trojan I power plant

    International Nuclear Information System (INIS)

    Bloyd, C.N.; Singleton, N.R.; Ciaramitaro, W.

    1976-05-01

    The internals vibration measurement program carried out on the Trojan-1 reactor during preoperational testing is described. The flow induced response of a 17 x 17 guide tube and the neutron pad core barrel were deduced from the plant test data and compared with the expected responses. The results showed good agreement with expected vibration levels

  1. Testing of the effect of the entry beam tube windows of the silicon detectors of the ionisation radiation

    International Nuclear Information System (INIS)

    Kopestansky, J.; Tykva, R.; Stanek, S.

    1995-01-01

    This paper deals with testing of the entry beam tube windows of the silicon detectors of the ionisation radiation with surface barrier.The influence of the parameters of basic material and modified technologic preparation on the size and homogeneity of the windows was tested

  2. Some problems in the technique of high-voltage testing of the accelerating tube gaps in electrostatic accelerators

    International Nuclear Information System (INIS)

    Romanov, V.A.; Ivanov, V.V.; Mukhametshin, V.I.; Dmitriev, E.P.; Kidalov, A.I.

    1983-01-01

    Problems arising during high-voltage testing and training of accelerating taubes of electrostatic accelrators are discussed. A rig and technique of the accelerating tube testing and program designed for the processing of the data obtained and sorting out of the samples investigated are described

  3. Study of tensile test behavior of austenitic stainless steel type 347 seamless thin-walled tubes in cold worked condition

    Energy Technology Data Exchange (ETDEWEB)

    Terui, Clarice, E-mail: clarice.terui@marinha.mil.br [Centro Tecnológico da Marinha em São Paulo (CINA/CTMSP), Iperó, SP (Brazil). Centro Industrial Nuclear da Marinha; Lima, Nelson B. de, E-mail: nblima@ipen.br [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNE-SP), Sao Paulo, SP (Brazil)

    2017-07-01

    These austenitic stainless steel type 347 seamless thin-walled tubes are potential candidates to be used in fuel elements of nuclear power plants (as PWR - Pressurized Water Reactor). So, their metallurgical condition and mechanical properties, as the tensile strength and yield strength, normally are very restrict in demanding project and design requirements. Several full size tensile tests at room temperature and high temperature (315 deg C) were performed in these seamless tubes in cold-worked condition. The results of specified tensile and yield strengths were achieved but the elongation of the tube, in the geometry of the component, could not be measured at high temperature due to unconventional mode of rupture (helical mode without separation of parts). The average value of elongation was obtained from stress-strain curves of hot tensile tests and was around 5%. The results obtained in this research show that this behavior of the full size tensile test samples of thin-walled tube (wall thickness less than 0.5 mm) in high temperature (315°C) is due to the combination of the manufacturing process, the material (crystallographic structure and chemical composition) and the final geometry of the component. In other words, the strong crystallographic texture of material induced by tube drawing process in addition with the geometry of the component are responsible for the behavior in hot uniaxial tensile tests. (author)

  4. Single Tube Rupture at Cold Side of Steam Generator Simulation Test Report Using the ATLAS

    International Nuclear Information System (INIS)

    Kang, Kyoung Ho; Park, Hyun Sik; Cho, Seok

    2010-12-01

    In this study, a postulated SGTR event of the APR1400 was experimentally investigated with the ATLAS. In order to simulate a double-ended rupture of a single U-tube in the APR1400, the SGTR-CL-01 test was performed with the ATLAS. The main objectives of this test were not only to provide a physical insight into the system response of the APR1400 during the SGTR but also to produce integral effect experimental data to validate the safety analysis code. In the present report, major thermal-hydraulic phenomena such as the system pressures, the collapsed water levels, and the break flow rate were presented and discussed. Following the reactor trip induced by high steam generator level (HSGL) signal, the primary system pressure decreased and the secondary system pressure increased until the MSSVs was opened. The MSSVs repeated on and off status depending on the secondary system pressure during the whole test period. Due to the break flow, the collapsed water level of the affected steam generator showed milder decrease than that of the intact steam generator. This integral effect test data will be used to evaluate the prediction capability of existing safety analysis codes of the MARS and the RELAP5 as well as the SPACE code. Furthermore, this data can be utilized to identify any code deficiency for a SGTR simulation, especially for DVI-adapted plants

  5. Experimental evaluation of emergency operating procedures on multiple steam generator tube rupture in INER integral system test facility

    International Nuclear Information System (INIS)

    Liu, T.J.; Lin, Y.M.; Lee, C.H.; Chang, C.Y.; Hong, W.T.

    1997-01-01

    The multiple steam generator tube rupture (SGTR) scenario in Westinghouse type pressurized water reactor (PWR) has been investigated at the Institute of Nuclear Energy Research (INER) Integral System Test (IIST) facility. This reduced-height and reduced-pressure test facility was designed to simulate the main features of Maanshan nuclear power plant. The SGTR test scenario assumes the double-ended break of one-, two- and six- tubes without other failures. The major operator actions follow the related symptom-oriented Emergency Operating Procedure (EOP) on the reference plant. This study focuses on the investigation of thermal-hydraulics phenomena and the adequacy of associated EOP to limit primary-to-secondary leakage. Through this study, it is found that the adequacy of current EOP in minimizing the radioactivity release demands early substantial operator involvement, especially in the multi-tubes break events. Also, the detailed mechanism of the main thermal-hydraulic phenomena during the SGTR transient are explored. (author)

  6. Vibration tests on single heat exchanger tubes in air and static water

    International Nuclear Information System (INIS)

    Collinson, A.E.; Warneford, I.P.

    1978-07-01

    The vibrational characteristics of a 7 span straight tube and a 26 span U-tube have been investigated for the effects of fluid medium (air/water), tube-grid clearance, tube-grid contact force, vibration transmission and scale. Measured frequency response and mode shapes compared favourably with theoretical values, vibration with pin-pin tube support being most readily excited. The frequency reduction on immersion in water corresponded to an added mass equivalent to the liquid displaced mass. Dynamic magnifiers varied in the range 12 to 135 with mean values of 30 to 40 in water and 45 to 60 in air. Principal vibration modes and damping values were reproducible in a half-scale model of a U-tube. (author)

  7. Multifrequency Eddy current testing of heat exchange tubes with a rotating probe

    International Nuclear Information System (INIS)

    Levy, R.

    1982-01-01

    Multi-frequency eddy current analyses have been used in France industrially since 1975. In light of the experienced gained during many steam generator inspections, this technique was applied to the examination of sheet and tube heat exchangers featuring tubes in very different materials such as copper, stainless steel and titanium. The principle of multi-frequency Eddy current inspection is first reviewed, using the example of a condenser with nickel alloy tubes (Inconel, Incoloy). This is followed by the description of a specific application of this technique to a condenser with titanium tubes, analyzed with a rotating local probe [fr

  8. Sex in a test tube: testing the benefits of in vitro recombination.

    Science.gov (United States)

    Pesce, Diego; Lehman, Niles; de Visser, J Arjan G M

    2016-10-19

    The origin and evolution of sex, and the associated role of recombination, present a major problem in biology. Sex typically involves recombination of closely related DNA or RNA sequences, which is fundamentally a random process that creates but also breaks up beneficial allele combinations. Directed evolution experiments, which combine in vitro mutation and recombination protocols with in vitro or in vivo selection, have proved to be an effective approach for improving functionality of nucleic acids and enzymes. As this approach allows extreme control over evolutionary conditions and parameters, it also facilitates the detection of small or position-specific recombination benefits and benefits associated with recombination between highly divergent genotypes. Yet, in vitro approaches have been largely exploratory and motivated by obtaining improved end products rather than testing hypotheses of recombination benefits. Here, we review the various experimental systems and approaches used by in vitro studies of recombination, discuss what they say about the evolutionary role of recombination, and sketch their potential for addressing extant questions about the evolutionary role of sex and recombination, in particular on complex fitness landscapes. We also review recent insights into the role of 'extracellular recombination' during the origin of life.This article is part of the themed issue 'Weird sex: the underappreciated diversity of sexual reproduction'. © 2016 The Author(s).

  9. Approximating a free-field blast environment in the test section of an explosively driven conical shock tube

    Science.gov (United States)

    Stewart, J. B.

    2018-02-01

    This paper presents experimental data on incident overpressures and the corresponding impulses obtained in the test section of an explosively driven 10° (full angle) conical shock tube. Due to the shock tube's steel walls approximating the boundary conditions seen by a spherical sector cut out of a detonating sphere of energetic material, a 5.3-g pentolite shock tube driver charge produces peak overpressures corresponding to a free-field detonation from an 816-g sphere of pentolite. The four test section geometries investigated in this paper (open air, cylindrical, 10° inscribed square frustum, and 10° circumscribed square frustum) provide a variety of different time histories for the incident overpressures and impulses, with a circumscribed square frustum yielding the best approximation of the estimated blast environment that would have been produced by a free-field detonation.

  10. Fluid-Elastic Instability Tests on Parallel Triangular Tube Bundles with Different Mass Ratio Values under Increasing and Decreasing Flow Velocities

    Directory of Open Access Journals (Sweden)

    Xu Zhang

    2016-01-01

    Full Text Available To study the effects of increasing and decreasing flow velocities on the fluid-elastic instability of tube bundles, the responses of an elastically mounted tube in a rigid parallel triangular tube bundle with a pitch-to-diameter ratio of 1.67 were tested in a water tunnel subjected to crossflow. Aluminum and stainless steel tubes were tested, respectively. In the in-line and transverse directions, the amplitudes, power spectrum density functions, response frequencies, added mass coefficients, and other results were obtained and compared. Results show that the nonlinear hysteresis phenomenon occurred in both tube bundle vibrations. When the flow velocity is decreasing, the tubes which have been in the state of fluid-elastic instability can keep on this state for a certain flow velocity range. During this process, the response frequencies of the tubes will decrease. Furthermore, the response frequencies of the aluminum tube can decrease much more than those of the stainless steel tube. The fluid-elastic instability constants fitted for these experiments were obtained from experimental data. A deeper insight into the fluid-elastic instability of tube bundles was also obtained by synthesizing the results. This study is beneficial for designing and operating equipment with tube bundles inside, as well as for further research on the fluid-elastic instability of tube bundles.

  11. Corrosion tests in Baltic sea water on heat exchanger tubes of various metallic materials

    International Nuclear Information System (INIS)

    Henrikson, S.; Knutsson, L.

    1975-05-01

    Seventeen different tube materials have been exposed to continuous and intermittent flow in Baltic Sea water (0.4 % Cl - ) at 50 deg C for a maximum of 15 000 hours. During testing the specimens have been examined at certain intervals. After testing the specimens have been examined visually and metallographically. The following materials were completely resistant: titanium, CuNi30Mn1Fe, Alloy 825 and the austenitic steels Cr18Ni24Mo4.5, Cr20Ni25Mo4.5Cu and Cr24Ni24Mo2Ti. The ferritic-austenitic steels Cr18Ni5Mo2Si and Cr25Ni5Mo1.5 on the other hand, seem to be attacked by local intercrystalline corrosion in the vicinity of the welds. The same type of attack occurs, against expectations, even in the entirely ferritic steels, especially in Cr21Mo3Ti; this attack was however shown to be caused by surface carburization. Admiralty brass (2.5 m/s), aluminium brass (3.0 m/s) and CuNi10Fe1Mn (3.5 m/s) have been attacked by erosion corrosion. The same type of attack, although to a considerably smaller extent, has also been observed for the three aluminium materials (2.5 m/s). (author)

  12. Fireside corrosion testing of candidate superheater tube alloys, coatings, and claddings -- Phase 2

    Energy Technology Data Exchange (ETDEWEB)

    Blough, J.L.; Seitz, W.W. [Foster Wheeler Development Corp., Livingston, NJ (United States)

    1997-12-01

    In Phase 1 a variety of developmental and commercial tubing alloys and claddings were exposed to laboratory fireside corrosion testing simulating a superheater or reheater in a coal-fired boiler. Phase 2 (in situ testing) has exposed samples of 347 RA-85H, HR3C, 253MA, Fe{sub 3}Al + 5Cr, 310 Ta modified, NF 709, 690 clad, and 671 clad for approximately 4,000, 12,000, and 16,000 hours to the actual operating conditions of a 250-MW coal-fired boiler. The samples were assembled on an air-cooled, retractable corrosion probe, the probe was installed in the reheater activity of the boiler and controlled to the operating metal temperatures of an existing and advanced-cycle coal-fired boiler. The results will be presented for the preliminary metallurgical examination of the corrosion probe samples after 16,000 hours of exposure. Continued metallurgical and interpretive analysis is still on going.

  13. Mechanical Tests Plan after Neutron Irradiation for SMART SG Tube Materials in a Hot Cell

    International Nuclear Information System (INIS)

    Ahn, Sang Bok; Baik, Seung Jai; Kim, Do Sik; Yoo, Byung Ok; Jung, Yang Hong; Song, Woong Sub; Choo, Kee Nam; Park, Jin Seok; Lee, Yong Sun; Ryu, Woo Seog

    2010-01-01

    An advanced integral PWR, SMART (System- Integrated Modular Advanced ReacTor) is being developed in KAERI. It has compact size and a relatively small power rating compared to a conventional reactor. The main components such as the steam generators, main circulation pumps are located in the reactor vessel. Therefore they are damaged from neutron irradiations generated from nuclear fuel fissions during operation. The SMART SG tubes which are 17 mm in a diameter and 2.5 mm in a thickness will be made of Alloy 690. To ensure the operation safety the post irradiation examinations is necessary to evaluate the deterioration levels of various original properties. Specially the amount of mechanical properties change should be reflected and revised to design data. For that tensile, fracture, hardness test are planned and under preparations. In this paper the detailed plans are reviewed. Three kinds of materials having different heat treatment procedures are prepared to fabricate specimens. The capsules installed the specimens are going to be irradiated in HANARO. Finally the tests for them will be performed in IMEF, Irradiated Materials Examination Facility at KAERI

  14. Atmospheres in a Test Tube: state of the art at the Astronomical Observatory of Padova.

    Science.gov (United States)

    Erculiani, M. S.; Claudi, R.; Cocola, L.; Giro, E.; La Rocca, N.; Morosinotto, T.; Poletto, L.; Barbisan, D.; Billi, D.; Bonato, M.; D'Alessandro, M.; Galletta, G.; Meneghini, M.; Trivellin, N.; Cestelli Guidi, M.; Pace, E.; Schierano, D.; Micela, G.

    At the Astronomical observatory of Padova we are trying to answer some questions about the detectability of biosignatures in the exoplanetary atmospheres, working in the framework of the project Atmosphere in a Test Tube. In particular we are investigating how the presence of photosynthetic biota living on the surface of a planet orbiting in the HZ of an M type star may modify the atmospheric gas abundances. This can be achieved in laboratory with an environmental simulator called MINI - LISA. The simulator allows to modify the temperature and the pressure inside a test chamber, where a selected population of photosynthetic bacteria is arranged. We'll focalize our experiments on the following bacteria: Acaryochloris marina, Halomicronema hongdechloris, Leptolyngbya sp.1 and Chlorogloeopsis fritschii. The first two bacteria are naturally provided with NIR light metabolizers, like Chl-d and Chl-f, while the last two can develop such pigments if grown in NIR light. The experiment will lead us to obtain useful data to be compared with the ones expected either by the future space missions (JWST, ARIEL) and ground based new instrumentation (SPHERE@VLT; GPI@GEMINI; PCS@E-ELT). In this talk we discuss the layout of the experiment and its state of art.

  15. Fragmentation of Solid Materials Using Shock Tubes. Part 2: First Test Series in a Large Diameter Shock Tube

    Science.gov (United States)

    2017-12-01

    series used improved experimental techniques to reduce obscuration due to smoke and fire which, again, increased the number of observed fragments (iii...minimally-reinforced concrete masonry unit (CMU) wall, and one 8-ft x 8-ft reinforced concrete panel, each carefully fabricated and mounted to replicate...develops a vertical compressive force that resists horizontal flexure. Figure 4. A view of CMU sample set-up used in Test 20. 6 Figure 5

  16. Post test analyses of Revisa benchmark based on a creep test at 1100 Celsius degrees performed on a notched tube

    International Nuclear Information System (INIS)

    Fischer, M.; Bernard, A.; Bhandari, S.

    2001-01-01

    In the Euratom 4. Framework Program of the European Commission, REVISA Project deals with the Reactor Vessel Integrity under Severe Accidents. One of the tasks consists in the experimental validation of the models developed in the project. To do this, a benchmark was designed where the participants use their models to test the results against an experiment. The experiment called RUPTHER 15 was conducted by the coordinating organisation, CEA (Commissariat a l'Energie Atomique) in France. It is a 'delayed fracture' test on a notched tube. Thermal loading is an axial gradient with a temperature of about 1130 C in the mid-part. Internal pressure is maintained at 0.8 MPa. This paper presents the results of Finite Element calculations performed by Framatome-ANP using the SYSTUS code. Two types of analyses were made: -) one based on the 'time hardening' Norton-Bailey creep law, -) the other based on the coupled creep/damage Lemaitre-Chaboche model. The purpose of this paper is in particular to show the influence of temperature on the simulation results. At high temperatures of the kind dealt with here, slight errors in the temperature measurements can lead to very large differences in the deformation behaviour. (authors)

  17. A comparison of the test tube and the dialysis tubing in vitro methods for estimating the bioavailability of phosphorus in feed ingredients for swine.

    Science.gov (United States)

    Bollinger, David W; Tsunoda, Atsushi; Ledoux, David R; Ellersieck, Mark R; Veum, Trygve L

    2005-05-04

    The validity of a simplified in vitro test tube (TT) method was compared with a more complicated dialysis tubing (DT) method to estimate the percentage of available phosphorus (P) in 41 plant origin and five animal origin feed ingredients for swine. The TT method using 1.0 or 0.25 g samples was compared with the DT method using 1.0 g samples at two pancreatic incubation times (2 vs 4 h) in a 3 x 2 factorial arrangement of treatments. Each DT and TT method treatment was replicated three and six times, respectively. Both methods utilize three enzymatic digestions: (i) predigestion with endoxylanase and beta-glucanase for 1 h, (ii) pepsin digestion for 2 h, and (iii) pancreatin digestion for 2 or 4 h. For the TT method, the entire procedure was conducted in a 50 mL conical centrifuge tube and replicated six times. For the DT method, the first two digestions were conducted in a 10 mL plastic syringe before the contents were quantitatively transferred into a segment of DT for the pancreatic digestion. The percentages of hydrolyzed P for plant origin ingredients measured by the DT method using 1.0 g samples and the TT method using 0.25 g samples were highly correlated (r = 0.94-0.97, P or = 0.4) with published in vivo available P values. In conclusion, the accuracy and validity of the TT method using 0.25 g samples with a 2 h pancreatic digestion time was equal to or superior to the DT method using 1.0 g samples with a 4 h pancreatic digestion time for estimating P availability in plant origin feed ingredients.

  18. Field survey and laboratory tests on composite materials case of GRP (Glass Fiber Reinforced Polyester tubes for water suply

    Directory of Open Access Journals (Sweden)

    Radu Hariga

    2013-09-01

    Full Text Available In the Moldova land, were made two lines of water adduction, having 6000 m length and 40 m slope, or 1/150 slope. The water supply component tubes were disposed under the plant: The tubes are made of glass – reinforced thermosetting plastics (GRP. After about 180 days of operation, one of the lines showed severe deterioration of the quality pipe components. This paper deals with some laboratory tests in order to detect the failure cases of the pipelines components.

  19. Heat transfer test in a vertical tube using CO2 at supercritical pressures

    International Nuclear Information System (INIS)

    Kim, Hwan Yeol; Kim, Hyungrae; Song, Jin Ho; Cho, Bong Hyun; Bae, Yoon Yeong

    2007-01-01

    Heat transfer test facility, SPHINX (Supercritical Pressure Heat Transfer Investigation for NeXt Generation), was constructed at KAERI (Korea Atomic Energy Research Institute) for an investigation of the thermal-hydraulic behaviors of supercritical CO 2 at the various geometries of the test section. The test data will be used for the reactor core design of the SCWR (SuperCritical Water-cooled Reactor). As a working fluid, CO 2 was selected to make use of the low critical pressure and temperature of CO 2 compared with water. An experimental study was carried out in the SPHINX to investigate the characteristics of heat transfer and pressure drop at a vertical single tube with an inside diameter of 4.4 mm in case of an upward flow of supercritical CO 2 . The heat and mass fluxes were varied at a given pressure. The mass flux was in the range of 400-1,200 kg/m 2 s and the heat flux was chosen up to 150 kW/m 2 . The selected pressures were 7.75, 8.12, and 8.85 MPa. A heat transfer deterioration occurred at the lower mass fluxes. The experimental heat transfer coefficients were compared with the ones predicted by several existing correlations. The standard deviation was about 20% for each correlation and an apparent discrepancy was not found among the correlations. The major components of the pressure drop were a gravitational pressure drop and a frictional pressure drop. The frictional pressure drop increases as the mass flux and heat flux increase. (author)

  20. Dynamic loads on human and animal surrogates at different test locations in compressed-gas-driven shock tubes

    Science.gov (United States)

    Alay, E.; Skotak, M.; Misistia, A.; Chandra, N.

    2018-01-01

    Dynamic loads on specimens in live-fire conditions as well as at different locations within and outside compressed-gas-driven shock tubes are determined by both static and total blast overpressure-time pressure pulses. The biomechanical loading on the specimen is determined by surface pressures that combine the effects of static, dynamic, and reflected pressures and specimen geometry. Surface pressure is both space and time dependent; it varies as a function of size, shape, and external contour of the specimens. In this work, we used two sets of specimens: (1) anthropometric dummy head and (2) a surrogate rodent headform instrumented with pressure sensors and subjected them to blast waves in the interior and at the exit of the shock tube. We demonstrate in this work that while inside the shock tube the biomechanical loading as determined by various pressure measures closely aligns with live-fire data and shock wave theory, significant deviations are found when tests are performed outside.

  1. Construction and test of high precision drift-tube (sMDT) chambers for the ATLAS muon spectrometer

    CERN Document Server

    Nowak, Sebastian; Kroha, Hubert; Schwegler, Philipp; Sforza, Federico

    2014-01-01

    For the upgrade of the ATLAS muon spectrometer in March 2014 new muon tracking chambers (sMDT) with drift-tubes of 15 mm diameter, half of the value of the standard ATLAS Monitored Drift-Tubes (MDT) chambers, and 10~$\\mu$m positioning accuracy of the sense wires have been constructed. The new chambers are designed to be fully compatible with the present ATLAS services but, with respect to the previously installed ATLAS MDT chambers, they are assembled in a more compact geometry and they deploy two additional tube layers that provide redundant rack information. The chambers are composed of 8 layers of in total 624 aluminium drift-tubes. The assembly of a chamber is completed within a week. A semi-automatized production line is used for the assembly of the drift-tubes prior to the chamber assembly. The production procedures and the quality control tests of the single components and of the complete chambers will be discussed. The wire position in the completed chambers have been measured by using a coordinate me...

  2. Manufacturing immunity to disease in a test tube: the magic bullet realized.

    Science.gov (United States)

    Lerner, Richard A

    2006-12-11

    Although it took over one hundred years, Ehrlich's concept of the magic bullet is now a reality. Today, therapeutic antibodies are, arguably, the most important class of new drugs for the treatment of illnesses ranging from Alzheimer's disease to cancer. The emergence of therapeutic antibodies had to wait for advances in immunochemistry that allowed construction of antibodies in vitro. The centerpiece of the new technology is the combinatorial antibody library, which essentially allows one to synthesize an artificial immune system with a diversity that exceeds that of the natural repertoire. The construction of such libraries was perceived to be difficult because, if the natural immune system was to be used as the starting material, construction of the libraries would entail protocols that are the opposite of usual cloning. In gene cloning one starts with complexity and reduces it to a singularity. In the generation of diversity by construction of combinatorial antibody libraries, one starts with a collection of clones, randomly expands their complexity, and then returns them to recoverable singularities. The methods developed to accomplish this seemingly formidable task now allow construction of antibodies in a test tube to any antigen. These synthetic antibodies may be qualitatively and quantitatively superior to those of nature.

  3. Inspection of heat transfer tubes after mock-up tests of miniaturized apparatus for the acid recovery evaporator. Contract research

    International Nuclear Information System (INIS)

    Hamada, Shozo; Fukaya, Kiyoshi; Kato, Chiaki; Yanagihara, Takao; Doi, Masamitu; Kiuchi, Kiyoshi

    2001-10-01

    The demonstration test for the acid recovery evaporator and the dissolver used in the major equipment of Rokkasho Reprocessing Plant (RRP), has been carried out. The mock-up miniature equipment has been employed to it. This test had been performed from April in 1998. The total time of demonstration test using the mock-up equipment is about two and half years, which corresponds to about 20,000 hours. After that, four of the seven heat transfer tubes used in the evaporator were drawn out and the corrosion level and the mechanical properties were evaluated for one of them. As a result, intergranular corrosion was recognized in the inner surface of the heat transfer tube and the corrosion depth at the grain boundary was statistically shown to be about one grain from the inner surface. Further, no change in mechanical properties was observed and growth of intergranular cracks in the inner surface of the specimen was found after flattering test. (author)

  4. Using an ultra-high speed camera to capture a tube expansion test

    CSIR Research Space (South Africa)

    Snyman, Izak M

    2016-09-01

    Full Text Available of the tube was estimated by viewing each image and extracts the expansion position in terms of pixels at specific locations, using the PFV software from Photron. Fifteen of the 32 images were used for this exercise....

  5. Evaluation of the inner wall axial cracks of steam generator tubes by eddy current test

    International Nuclear Information System (INIS)

    Hur, Do Haeng; Choi, Myung Sik; Lee, Doek Hyun; Han, Jung Ho

    2001-01-01

    For the enhancement of ECT reliability on the primary water stress corrosion cracks of nuclear steam generator tubes, it is important to comprehend the signal characteristics on crack morphology and to select an appropriate probe type. In this paper, the sizing accuracy and the detectability for the inner wall axial cracks of tubes were quantitatively evaluated using the electric discharge machined notches and the corrosion cracks which were developed on the operating steam generator tubes. The difference of eddy current signal characteristics between pancake and axial coil were also investigated. The results obtained from this study provide a useful information for more precise evaluation on the inner wall axial cracks of steam generator tubes.

  6. [Partial thyroxine binding globulin deficiency in test tube infants: report of cases and literature review].

    Science.gov (United States)

    Fang, Y L; Wang, C L; Liang, L

    2016-06-02

    To investigate the clinical characteristics of twins with thyroxine binding globulin (TBG) deficiency and to find SERPINA7 gene mutations. Data(2015) related to clinical characteristics, serum biochemistry, gene mutations and pedigree of two children with TBG deficiency were collected in the First Affiliated Hospital of College of Medicine, Zhejiang University. The related literature was searched form China National Knowledge Infrastructure, Wanfang Data Knowledge Service Platform, National Center for Biotechnology Information and PubMed (up to December 2015) by using search terms "Thyroxine binding globulin deficiency, gene, mutation" . Both patients were diagnosed as central hypothyroidism at the beginning and treated with L-thyroxine. Both of the identical twins of the triplet were observed for mutation in exon3, c. 631G﹥A(p.A211T), a new mutation had not been reported, but their parents and another non-identical triplet brother were normal. Literature review showed that 23 foreign cases with SERPINA7 gene mutation had been reported, however, no Chinese with SERPINA7 gene mutation had been reported. Among reported cases it was shown that SERPINA7 gene mutations located in exon, intron, promoter and enhancer. Up to now, 49 variants had been identified, 41 of them located in the mutated genes. Including these two cases, patients with thyroxine binding globulin deficiency were characterized by reduced serum TH levels, but normal free TH and TSH and absence of clinical manifestations. The new mutation of SERPINA7 gene c. 631G﹥A(p.A211T)is not transmitted via the known X chromosome linked heredity, and as the cases were test tube triplet infants, it is a de novo mutation. The serum thyroid function tests of TBG deficiency showed decreased TT4, TT3 and normal TSH and TBG deficiency is often misdiagnosed as central hypothyroidism.

  7. Thermal-hydraulic tests of steam-generator tube-support-plate crevices. Volume 2. Appendixes I through S. Final report

    International Nuclear Information System (INIS)

    Cassell, D.S.; Vroom, D.W.

    1983-01-01

    A test program was conducted to determine for selected steam generator tube supports the thermal/hydraulic conditions at the inception of dryout as indicated by a tube wall temperature excursion, to determine the pressure drop across the supports, and to obtain photographic documentation of the flow upstream and downstream of the supports. A multi-tube steam generator model was used and testing performed over the range of typcal PWR steam generator operating conditions. These appendices contain information on instrumentation calibration, test model and loop calibration, error analysis, test model thermal-hydraulic analyses, index of lab materials and log sheets, index of two-phase flow still photographs, index of high speed movies and video, test data printouts, test model and loop fabrication drawings, procedure for silver brazing tubewall thermocouples, and procedure for esablishing tube-tube support line contact

  8. Wastage-resistant characteristics of 12Cr steel tube material. Small leak sodium-water reaction test

    International Nuclear Information System (INIS)

    Shimoyama, Kazuhito

    2004-03-01

    In the water leak accident of a steam generator designed for a sodium cooled reactor in the Feasibility Study, the localization of tube failure propagation by using an advanced water leak detector will be required from the viewpoints of the safety and economical efficiency of the plant. So far, the conventional knowledge and analytical tools have been used in the investigation and evaluation of water leak phenomenon; nevertheless, there was neither test data nor the study of quantitative evaluation on the corrosion behavior, so-called wastage-resistant characteristics, of 12Cr steel tube material in sodium-water reactions. Wastage tests for the 12Cr steel tube material were conducted in small water leaks by use of the Sodium-Water Reaction Test Rig (SWAT-1R), and the data of wastage rate were obtained in the parameter of water leak rate under the constant sodium temperature and distance between leak and target tubes. The test results lead to the following conclusions: (1) The wastage-resistibility of 12Cr steel is 1.6 times greater than that of 9Cr steel and is 2.7 times greater than that of 2.25Cr-1Mo steel. (2)The wastage-resistibility of 12Cr steel increases in smaller water leaks; especially in water leak rates of 1 g/sec or less, it is more excellent than that of SUS321 stainless steel used as Monju superheater tube material. (3) Based on the correlation of wastage rate for the 9Cr steel, the correlation for the 12Cr steel has been obtained to be used for the evaluation of tube failure propagation. As the correlation of wastage rate for the 12Cr steel is based on the correlation for the 9Cr steel, it gives enough conservatism in smaller water leaks. To serve in accurately evaluating the tube failure propagation in smaller water leaks, it is necessary to obtain new correlation of wastage rate for the 12Cr steel based on the data in the wide range of water leak rates. (author)

  9. [Test anxiety: associations with personal and family variables].

    Science.gov (United States)

    Rosário, Pedro; Núñez, José Carlos; Salgado, Ana; González-Pienda, Julio A; Valle, Antonio; Joly, Cristina; Bernardo, Ana

    2008-11-01

    Test anxiety is a common behavior among students facing social pressure centered on mastery. Only a few studies have analyzed the relations between test anxiety, academic procrastination, personal and family variables and math grades. This work focus on the analysis of the impact of students' social-personal variables such as parents' education level, number of siblings and under-achievement by performing ANOVAs in two samples of 533 and 796 students from junior high-school. Corroborating the findings in other studies, the data stress that test anxiety is higher in girls and decreases when students' parents have higher educational levels, with the number of courses flunked, and when students' math grades were lower. Test anxiety and procrastination correlate positive and significantly. Findings are discussed and compared with those of previous researches. The implications for teaching practice are also analyzed.

  10. A simple in vitro test tube method for estimating the bioavailability of phosphorus in feed ingredients for swine.

    Science.gov (United States)

    Bollinger, David W; Tsunoda, Atsushi; Ledoux, David R; Ellersieck, Mark R; Veum, Trygve L

    2004-04-07

    A simplified in vitro test tube (TT) method was developed to estimate the percentage of available P in feed ingredients for swine. The entire digestion procedure with the TT method consists of three consecutive enzymatic digestions carried out in a 50-mL conical test tube: (1) Pre-digestion with endo-xylanase and beta-glucanase for 1 h, (2) peptic digestion for 2 h, and (3) pancreatic digestion for 2 or 4 h. The TT method is simpler and much easier to perform compared to the dialysis tubing (DT) method, because dialysis tubing is not used. Reducing sample size from 1.0 to 0.25 g for the TT method improved results. In conclusion, the accuracy and validity of the TT method is equal to that of our more complicated DT method (r = 0.97, P < 0.001), designed to mimic the digestive system of swine, for estimating the availability of P in plant-origin feed ingredients.

  11. Tests for development of estimation technology of reactor core deformation. Report No.1: fundamental mechanical properties of wrapper tube (test report)

    International Nuclear Information System (INIS)

    Nishiura, Takeo; Shimazaki, Yuji; Horikiri, Morito

    1998-10-01

    Mechanical properties such as local contact compression stiffness, bending stiffness, deformation properties, material properties, and friction properties of a wrapper tube structure were clarified experimentally, which can be used as the basic data for development of estimation technology of reactor core deformation. Contents of the Tests data as follows: (1) Effects of load supporting boundary conditions, whether or not a contact-proof pad is attached, and length of duct, on cross section deformation of wrapper tube were made clear as the local contact compression stiffness characteristics. (2) Bending stiffness does not depend on the difference of load supporting boundary conditions. The property of cross section deformation under bending load was obtained. (3) The deformation modes and the strain distributions were obtained by the deformation tests of wrapper tube. (4) The stress-strain diagrams including plastic range under various strain variation rates were obtained by the material tests at room temperature. (5) The static and the dynamic friction coefficients by various contact angles and the contact loads between contact-proof pads of two wrapper tubes were obtained by friction property tests. (author)

  12. Operation of the UKK-2 facility for tube complex testing and way of its further improvement

    International Nuclear Information System (INIS)

    Ogarkov, N.V.; Senyutkin, P.A.; Silaev, A.N.; Topychkanov, V.V.

    1987-01-01

    The UKK-2 ultrasonic 8-channel facility for complex control is designed for control of continuity, wall thickness of 0.3-1.0 mm, inner diameter of tubes and external diameter of 7-15 mm. Utilization of UKK-2 increased reliability of control, stabilized tube quality at a higher level, increased control efficiency 2-3 times. The most noticeable shortcomings of the UKK-2 are as follows: impossibility of differential separation of tubes rejected by sizes, by rectifiable and nonrectifiable rejects as well as absence of devices for mechanized loading, unloading and grading the tubes. The flowsheet, design and technological shortcomings of the facility are discovered during its operation. Ways of further improvement of the facility are as follows: development of the system for control result analysis on the basis of a microcomputer, equipment with devices for loading, unloading and grading the tubes; development of more reliable electron devices and units, means of automated diagnostics and automated tuning, increase of the level of metrological provision, improvement of hardware and software of the facility

  13. Family system characteristics and psychological adjustment to cancer susceptibility genetic testing: a prospective study.

    NARCIS (Netherlands)

    Oostrom, I.I.H. van; Meijers-Heijboer, H.; Duivenvoorden, H.J.; Brocker-Vriends, A.H.; Asperen, C.J. van; Sijmons, R.H.; Seynaeve, C.; Gool, A.R. van; Klijn, J.G.M.; Tibben, A.

    2007-01-01

    This study examined prospectively the contribution of family functioning, differentiation to parents, family communication and support from relatives to psychological distress in individuals undergoing genetic susceptibility testing for a known familial pathogenic BRCA1/2 or Hereditary nonpolyposis

  14. Family system characteristics and psychological adjustment to cancer susceptibility genetic testing: a prospective study

    NARCIS (Netherlands)

    van Oostrom, I.; Meijers-Heijboer, H.; Duivenvoorden, H. J.; Bröcker-Vriends, A. H. J. T.; van Asperen, C. J.; Sijmons, R. H.; Seynaeve, C.; van Gool, A. R.; Klijn, J. G. M.; Tibben, A.

    2007-01-01

    This study examined prospectively the contribution of family functioning, differentiation to parents, family communication and support from relatives to psychological distress in individuals undergoing genetic susceptibility testing for a known familial pathogenic BRCA1/2 or Hereditary nonpolyposis

  15. Family system characteristics and psychological adjustment to cancer susceptibility genetic testing : a prospective study

    NARCIS (Netherlands)

    van Oostrom, I.; Meijers-Heijboer, H.; Duivenvoorden, H. J.; Brocker-Vriends, A. H. J. T.; van Asperen, C. J.; Sijmons, R. H.; Seynaeve, C.; Van Gool, A. R.; Klijn, J. G. M.; Tibben, A.

    This study examined prospectively the contribution of family functioning, differentiation to parents, family communication and support from relatives to psychological distress in individuals undergoing genetic susceptibility testing for a known familial pathogenic BRCA1/2 or Hereditary nonpolyposis

  16. Ultrasonic testing of canning tubes in stainless steel of the EL 4 reactor

    International Nuclear Information System (INIS)

    Prot, A.; Monnier, P.

    1964-01-01

    From all the methods possible for controlling thin cans the one chosen, for numerous reasons, vas that making use of ultrasonic techniques. A method has been developed which should make it possible to carry out a rapid and efficient industrial control of canning tubes, The reasons for the choice of the ultrasonic method are given in detail, together with the principles of the method and the actual control parameters. In the present state of our research, it should be possible to control at least 50 000 tubes a year. Improvements brought about in the details of the control technique itself should make it possible to increase this rate considerably. (authors) [fr

  17. Liquid scintillation systems and apparatus for measuring high-energy radiation emitted by samples in standard laboratory test tubes

    International Nuclear Information System (INIS)

    Benvenutti, R.A.

    1976-01-01

    Liquid scintillation detection system employs improved sample holders in which the cap of a glass vial is provided with a well for receiving a standard laboratory test tube containing a radioactive sample. The well is immersed in a liquid scintillator in the vial, the scintillator containing lead acetate solution to enhance its efficiency. A commercially available beta-counting liquid scintillation apparatus is modified to provide gamma-counting with the improved sample holders

  18. Nondestructive inspection of the tubes of TRIGA IPR-R1 reactor heat exchanger by eddy current testing

    International Nuclear Information System (INIS)

    Silva Junior, Silverio F.; Silva, Roger F.; Oliveira, Paulo F.; Barreto, Erika S.; Ribeiro, Isabela G.; Fraiz, Felipe C.

    2013-01-01

    The IPR-R1 TRIGA MARK 1 reactor is an open pool type reactor, cooled light water. It is used for research activities, personnel training and radioisotopes production, in operation since 1960 at the Nuclear Technology Development Center - CDTN/CNEN. It operates at a maximum thermal power of 100 kW and usually, the fuel cooling is done by natural circulation. If necessary, an external auxiliary cooling system, with a shell-and-tube type heat exchanger, can be used to improve the water heat removal. As part of the ageing management program of the reactor, a nondestructive evaluation of their heat exchanger stainless steel tubes will be performed, in order to verify its integrity. The examinations will be performed using the eddy current test method, which allows the detection and characterization of structural discontinuities in the wall of the tubes, if existing. For this purpose, probes and reference standards were designed and manufactured at CDTN facilities and test procedures were established and validated. In this paper, a description of the proposed infrastructure as well as the test methodology to be used in the examinations are presented and discussed. (author)

  19. DHC velocity comparison of CANDU Zr-2.5Nb pressure tube for the difference of test environments

    International Nuclear Information System (INIS)

    Cho, S. Y.; Kim, Y. S.; Oh, D. Z.; Yim, K. S.; Yim, Y. W.

    2001-01-01

    Zr-2.5Nb Pressure tube was used in the distilled water under high temperature and pressure. However, the evaluation of DHCV for pressure tube was limited in the air until now. Therefore, it was necessary for DHCV both in the air and in the distilled water under high temperature and pressure to evaluate. In advance, new DHC equipment simulating the real operating condition in the distilled water under high temperature and pressure was developed and DHCV test was conducted by this equipment. The test was carried out under simulated condition using distilled water of 250 .deg. C, 86bar and this result was compared with of DHCV in the air of 250 .deg. C. DHCV of the distilled water was ranged from 8.42x10 -8 to 9.92x 10 -8 m/s and the average value was 9.01x 10 -8 m/s. As compared with the air condition, it was found that characteristics of DHCV was not affected by the distilled water of high temperature and pressure. At the same temperature, DHCV of the irradiated pressure tube was faster than that of test result

  20. Improvement of Eddy Current testing methods of steam generator tubings due to field experience

    International Nuclear Information System (INIS)

    Comby, R.; Meurgey, P.; David, B.

    1985-01-01

    This paper presents the main stages of the long rotating probe developed by EDF, this probe detects stress corrosion cracks. The method has been validated by the examination of numerous cracked tubes that the probe detected before. Methods to better characterize the signals with regard to the defects are being improved to avoid a complementary examination of the rolling zone more particularly [fr

  1. High Mach Number Scramjet Test Flows in the X3 Expansion Tube

    Science.gov (United States)

    Gildfind, D. E.; Sancho, J.; Morgan, R. G.

    The University of Queensland (UQ) has two free-piston driven expansion tube facilities; X2 has a total length of 23 m and was originally commissioned in 1995 [1]; X3 is much longer at 62 m, and was commissioned in 2001 [2].

  2. Design and testing of access-tube TDR soil water sensor

    Science.gov (United States)

    We developed the design of a waveguide on the exterior of an access tube for use in time-domain reflectometry (TDR) for in-situ soil water content sensing. In order to optimize the design with respect to sampling volume and losses, we derived the electromagnetic (EM) fields produced by a TDR sensor...

  3. 9 CFR 147.1 - The standard tube agglutination test. 1

    Science.gov (United States)

    2010-01-01

    ... may be done with a suitable pencil on etched portions of the tube, or by means of fast-gum labels. (3..., high agglutinability, but are not sensitive to negative and nonspecific sera. The stock cultures may be... for at least 20 hours at 37 °C. (h) The results shall be recorded as: N, or − (negative) when the...

  4. Fast and Accurate Non-destructive Testing System for Inspection of Canning Tubes

    DEFF Research Database (Denmark)

    Gundtoft, Hans Erik; Nielsen, E.

    1973-01-01

    The authors describe the development of an inspection bench for the non-destructive examination of canning tubes. The bench is original in that the internal diameter is calculated from exact measurement of the outer diameter and the wall thickness. The transducers for inspection and control are r...

  5. Standard practice for in situ examination of ferromagnetic Heat-Exchanger tubes using remote field testing

    CERN Document Server

    American Society for Testing and Materials. Philadelphia

    2010-01-01

    1.1 This practice describes procedures to be followed during remote field examination of installed ferromagnetic heat-exchanger tubing for baseline and service-induced discontinuities. 1.2 This practice is intended for use on ferromagnetic tubes with outside diameters from 0.500 to 2.000 in. [12.70 to 50.80 mm], with wall thicknesses in the range from 0.028 to 0.134 in. [0.71 to 3.40 mm]. 1.3 This practice does not establish tube acceptance criteria; the tube acceptance criteria must be specified by the using parties. 1.4 Units—The values stated in either inch-pound units or SI units are to be regarded separately as standard. The values stated in each system may not be exact equivalents; therefore, each system shall be used independently of the other. Combining values from the two systems may result in nonconformance with the standard. 1.5 This standard does not purport to address all of the safety concerns, if any, associated with its use. It is the responsibility of the user of this practice to establ...

  6. Patient and Family Caregivers’ Experiences of Living With a Jejunostomy Feeding Tube After Surgery for Esophagogastric Cancer

    OpenAIRE

    Halliday, V.; Baker, M.; Thomas, A.L.; Bowrey, D.

    2017-01-01

    BACKGROUND: Jejunostomy feeding tubes (JFTs) can be used to provide nutrition support to patients who have had surgery for esophagogastric cancer. Although previous research reports how patients cope with a gastrostomy tube, little is known about the impact of having a JFT. The aim of this qualitative study was to explore how patients and their informal caregivers experience living with a JFT in the first months following surgery. METHODS: Participants were purposively sampled from a cohort o...

  7. Interventions to Educate Family Physicians to Change Test Ordering

    Directory of Open Access Journals (Sweden)

    Roger Edmund Thomas MD, PhD, CCFP, MRCGP

    2016-03-01

    Full Text Available The purpose is to systematically review randomised controlled trials (RCTs to change family physicians’ laboratory test-ordering. We searched 15 electronic databases (no language/date limitations. We identified 29 RCTs (4,111 physicians, 175,563 patients. Six studies specifically focused on reducing unnecessary tests, 23 on increasing screening tests. Using Cochrane methodology 48.5% of studies were low risk-of-bias for randomisation, 7% concealment of randomisation, 17% blinding of participants/personnel, 21% blinding outcome assessors, 27.5% attrition, 93% selective reporting. Only six studies were low risk for both randomisation and attrition. Twelve studies performed a power computation, three an intention-to-treat analysis and 13 statistically controlled clustering. Unweighted averages were computed to compare intervention/control groups for tests assessed by >5 studies. The results were that fourteen studies assessed lipids (average 10% more tests than control, 14 diabetes (average 8% > control, 5 cervical smears, 2 INR, one each thyroid, fecal occult-blood, cotinine, throat-swabs, testing after prescribing, and urine-cultures. Six studies aimed to decrease test groups (average decrease 18%, and two to increase test groups. Intervention strategies: one study used education (no change: two feedback (one 5% increase, one 27% desired decrease; eight education + feedback (average increase in desired direction >control 4.9%, ten system change (average increase 14.9%, one system change + feedback (increases 5-44%, three education + system change (average increase 6%, three education + system change + feedback (average 7.7% increase, one delayed testing. The conclusions are that only six RCTs were assessed at low risk of bias from both randomisation and attrition. Nevertheless, despite methodological shortcomings studies that found large changes (e.g. >20% probably obtained real change.

  8. Opinion and knowledge among hospital medical staff regarding diagnosis of diabetes and proper usage of a specific test tube for glucose analysis.

    Science.gov (United States)

    Bar-Dayan, Y; Bogaiov, A; Boaz, M; Landau, Z; Wainstein, J

    2014-02-01

    Accuracy of blood sugar values, as examined by glucose analysis, has significant importance on the diagnosis of diabetes and follow up of diabetes treatment. Usage of a designated test tube significantly improves the accuracy of measurement. Knowledge of the medical staff is a major determinant in the current usage of such a technology. The aim of the study was to assess the level of knowledge exhibited by medical staff in the diabetes field and specifically for the usage of a designated tube to test blood glucose level. A prospective study. The staff of the internal and surgical departments and outpatient clinics at the Wolfson Medical Center completed a questionnaire that assessed the level of knowledge about the designated glucose test tube, other randomly used test tubes, the parameters that influence the blood glucose values in a non-designated tube and the diagnosis of diabetes. A number of 160 questionnaires (50% from internal departments, 36% from surgical departments and 14% from outpatient clinics) were analysed. The majority of the staff members (65%) knew that diabetes is diagnosed by glucose levels in blood. Of the 35% that did not know, 91% were nurses. The majority (75%) knew that diabetes is diagnosed during fasting conditions; however, most of the staff indicated that 12 h is needed. Only 25% knew of the designated test tube, and most of the staff indicated that a regular chemistry tube was the tube of choice for them. The staff exhibited poor level of knowledge regarding the parameters that influence the quality of the test. Staff members are not aware of the various aspects of diabetes diagnosis and the designated test tube for glucose measurements, and most of them use a tube that gives inaccurate measurements, therefore there is an urgent need to improve diabetes knowledge among staff members. © 2013 John Wiley & Sons Ltd.

  9. Method for shaping polyethylene tubing

    Science.gov (United States)

    Kramer, R. C.

    1981-01-01

    Method forms polyethylene plastic tubing into configurations previously only possible with metal tubing. By using polyethylene in place of copper or stain less steel tubing inlow pressure systems, fabrication costs are significantly reduced. Polyethylene tubing can be used whenever low pressure tubing is needed in oil operations, aircraft and space applications, powerplants, and testing laboratories.

  10. Test and evaluation of the BBC CQK 200-4 modulator tube for the MFTF sustaining neutral beam power supply system

    International Nuclear Information System (INIS)

    Eckard, R.D.; Van Ness, H.W.; Hesselgrave, D.

    1979-01-01

    The BBC CQK 200-4 Tube was tested by Aydin at LLL, to confirm that it would switch 90 kV after conducting 88 amperes for 30 seconds. The CQK 200-4 is a recent modification of the CQK 200-3, an Rf transmitter tube designed for continuous loading, to increase the anode hold-off voltage to 150 kV. During the design life of the tube it will be subjected to 10 5 to 10 6 cyclic thermal loads. Two concerns are that (1) during the 30 second high current load, the screen grid may have excessive dissipation causing a loss of control of the tube, and (2) the cyclic temperature-induced stresses in the anode may cause fatigue failures that will reduce the tube's useful life. The first concern was addressed by performing full scale tests at the LLL test facility

  11. Contribution to perfecting eddy current testing of steam generator tubes of sodium cooled breeders: description of the Monacault loop for the study of sodium deposit influence

    International Nuclear Information System (INIS)

    Lapicore, A.; Lemarquis, J.C.; Oberlin, C.; Pigeon, M.

    1981-12-01

    In the event of sodium-water reaction in the steam generator of a sodium cooled breeder reactor, it is essential to be able to monitor the local loss of thickness of the tubes located in the reaction area. A method for monitoring the tubes by an eddy current probe is being developed for Super Phenix. The sodium deposits on the outer wall of the tubes, as well as their prolonged contact with high temperature sodium are likely to bring about a change in the signals picked up. A test loop, Monacault, has been built in order to clarify the importance of these parameters (effect of sodium deposits, reproducibility of the wetting at different temperatures). It includes three test cells containing the sample tubes having a total of 61 standard defects to be tested. The first results on the wetting of tubes are given and discussed [fr

  12. Flow mixing inside a control-rod guide tube – Experimental tests and CFD simulations

    International Nuclear Information System (INIS)

    Angele, Kristian; Odemark, Ylva; Cehlin, Mathias; Hemström, Bengt; Högström, Carl-Maikel; Henriksson, Mats; Tinoco, Hernan; Lindqvist, Hans

    2011-01-01

    This paper covers a combined experimental and computational effort carried out at Vattenfall Research and Development AB in order to study the thermal mixing in the annular region between a top tube and a control-rod stem. The low frequency thermal fluctuations in this region can result in problems with thermal fatigue and have caused cracks in the control-rod stems of several nuclear reactors (). The flow in the vertical annular region formed by the top tube and the control-rod stem is characterized by the mixing of hot bypass flow with cold crud-removal flow. The crud-removal flow is flowing upwards along the control-rod stem, and the warmer bypass flow is entering through eight horizontal holes positioned in the lower part of the guide tube and four holes in the upper part of the top tube, forming jets. Two full-scale models of a control rod, including the control-rod stem and the guide tube, were constructed. The first model, designed to work at atmospheric conditions, was made of Plexiglass, in order to be able to visualize the mixing process, whereas the second one was made of steel to allow for a higher temperature difference between the two flows, and the heating of the top tube. CFD simulations of the case at atmospheric conditions were also carried out. Both the experiments and the simulations showed that the mixing region between the cold crud-removal flow and the warm bypass flow is dominated by large flow structures coming from above. The process is characterized by low frequency, high amplitude temperature fluctuations. The process is basically hydrodynamic, caused by the downward transport of flow structures originated at the upper bypass inlets. The damping thermal effects through buoyancy is of secondary importance, as also the scaling analysis shows, however a slight damping of the temperature fluctuations can be seen due to natural convection due to a pre-heating of the cold crud-removal flow. The comparison between numerical and experimental

  13. Ferruleless coupled-cavity traveling-wave tube cold-test characteristics simulated with micro-SOS

    Science.gov (United States)

    Schroeder, Dana L.; Wilson, Jeffrey D.

    1993-01-01

    The three-dimensional, electromagnetic circuit analysis code, Micro-SOS, can be used to reduce expensive and time consuming experimental 'cold-testing' of traveling-wave tube (TWT) circuits. The frequency-phase dispersion and beam interaction impedance characteristics of a ferruleless coupled-cavity traveling-wave tube slow-wave circuit were simulated using the code. Computer results agree closely with experimental data. Variations in the cavity geometry dimensions of period length and gap-to-period ratio were modeled. These variations can be used in velocity taper designs to reduce the radiofrequency (RF) phase velocity in synchronism with the decelerating electron beam. Such circuit designs can result in enhanced TWT power and efficiency.

  14. Study on chromosome aberrations test determinated by micro-whole blood culture in vacuum blood collection tube

    International Nuclear Information System (INIS)

    Zhong Zhihong; Han Fang'an; Ge Qinjuan; Wu Xiao; Chen Juan

    2006-01-01

    Objective: To develop an easier and efficient method of culturing the chromosome and analyzing the aberrations in peripheral lymphocytes. Methods: Micro whole was cultured for 54 hours in home-made vacuum blood collection tube, and then collection, slice-making, microscopy detection for the chromosome aberrations was done. The difference of the results was analysed by comparing with the common method. Results: For 60 radiologists and 30 contrasts, the chromosome aberrations in peripheral lymphocytes were examed by this system, the lymphocytes and chromosome were clear and alive and easier to analyse. Compared with the common method, there was no significantly difference between the two analyzing results. Conclusion: The chromosome aberrations test by micro whole blood culture in vacuum blood collection tube is easier and efficient, and is worthy of being widely popularized. (authors)

  15. Lay out and materials for in pile tritium transport testing of breeder-inside-tube pin assemblies

    International Nuclear Information System (INIS)

    Alvani, C.; Casadio, S.; Mancini, M.R.; Nannetti, C.A.; Avon, J.; Ravel, S.; Pruzzo, G.; Terrosi; Roux, N.; Terlain, A.; and others.

    1994-01-01

    An irradiation experiment (90 FPD in SILOE reactor) has been designed in order to evaluate the in-situ effect of red-ox power of sweeping gas (helium with 100 vpm of H 2 /H 2 O with relative concentrations varying from pure H 2 to pure H 2 O ) on tritium removal from LiAlO 2 and Li 2 ZrO 3 ; and tritium permeation through AlSl-316L SS tubes with bare and coated surfaces. The conditions and materials explored were selected in order to test possible improvements with respect to critical issues for the 'Breeder Inside Tube' (BIT) blanket concept development. (author) 6 refs.; 4 figs.; 2 tabs

  16. Numerical simulations of eddy current testing signals of steam generator tubes by 3-D finite element method

    International Nuclear Information System (INIS)

    Sakai, Takayuki; Soneda, Naoki

    1996-01-01

    In every inspection of Japanese PWR plants, all of steam generator tubes are inspected using Eddy Current Testing (ECT) method. However, the relationships between the ECT signals and the defect shapes are known only for the representative shapes of defects. In order to improve the reliability of inspections and the capability of ECT probes, development of numerical simulation technique of the ECT signals for arbitrarily shaped defects is essential. In this study, three-dimensional finite element code is developed to simulate the ECT signals for any kinds of defects in the SG tubes. The code is fully vectorized so that it runs on the supercomputers very efficiently. The simulation results agree very well with the experimental results. Sensitivity analyses are performed to investigate the relationships between the defect shapes and the ECT signals. (author)

  17. Magnesium diboride on inner wall of copper tube: A test case for superconducting radio frequency cavities

    Directory of Open Access Journals (Sweden)

    Wenura K. Withanage

    2017-10-01

    Full Text Available Superconductor magnesium diboride is considered one of the viable materials to substitute bulk niobium for superconducting radio frequency cavities. Utilizing a MgB_{2} coating on the inner wall of a copper cavity will allow operation at higher temperatures (20–25 K than Nb cavities due to the high transition temperature of MgB_{2} (39 K and the high thermal conductivity of Cu. In this paper, we present results of MgB_{2} coating on Cu tubes with similar dimensions to a 3 GHz cavity, as the first step towards coating the actual cavity, using the hybrid physical chemical vapor deposition technique. The results show successful coating of a uniform MgB_{2} layer on the inner wall of the Cu tubes with T_{c} as high as 37 K.

  18. Magnesium diboride on inner wall of copper tube: A test case for superconducting radio frequency cavities

    Science.gov (United States)

    Withanage, Wenura K.; Lee, N. H.; Penmatsa, Sashank V.; Wolak, M. A.; Nassiri, A.; Xi, X. X.

    2017-10-01

    Superconductor magnesium diboride is considered one of the viable materials to substitute bulk niobium for superconducting radio frequency cavities. Utilizing a MgB2 coating on the inner wall of a copper cavity will allow operation at higher temperatures (20-25 K) than Nb cavities due to the high transition temperature of MgB2 (39 K) and the high thermal conductivity of Cu. In this paper, we present results of MgB2 coating on Cu tubes with similar dimensions to a 3 GHz cavity, as the first step towards coating the actual cavity, using the hybrid physical chemical vapor deposition technique. The results show successful coating of a uniform MgB2 layer on the inner wall of the Cu tubes with Tc as high as 37 K.

  19. Real time flaw detection and characterization in tube through partial least squares and SVR: Application to eddy current testing

    Science.gov (United States)

    Ahmed, Shamim; Miorelli, Roberto; Calmon, Pierre; Anselmi, Nicola; Salucci, Marco

    2018-04-01

    This paper describes Learning-By-Examples (LBE) technique for performing quasi real time flaw localization and characterization within a conductive tube based on Eddy Current Testing (ECT) signals. Within the framework of LBE, the combination of full-factorial (i.e., GRID) sampling and Partial Least Squares (PLS) feature extraction (i.e., GRID-PLS) techniques are applied for generating a suitable training set in offine phase. Support Vector Regression (SVR) is utilized for model development and inversion during offine and online phases, respectively. The performance and robustness of the proposed GIRD-PLS/SVR strategy on noisy test set is evaluated and compared with standard GRID/SVR approach.

  20. Design of a Kaplan turbine for a wide range of operating head -Curved draft tube design and model test verification-

    Science.gov (United States)

    KO, Pohan; MATSUMOTO, Kiyoshi; OHTAKE, Norio; DING, Hua

    2016-11-01

    As for turbomachine off-design performance improvement is challenging but critical for maximising the performing area. In this paper, a curved draft tube for a medium head Kaplan type hydro turbine is introduced and discussed for its significant effect on expanding operating head range. Without adding any extra structure and working fluid for swirl destruction and damping, a carefully designed outline shape of draft tube with the selected placement of center-piers successfully supresses the growth of turbulence eddy and the transport of the swirl to the outlet. Also, more kinetic energy is recovered and the head lost is improved. Finally, the model test results are also presented. The obvious performance improvement was found in the lower net head area, where the maximum efficiency improvement was measured up to 20% without compromising the best efficiency point. Additionally, this design results in a new draft tube more compact in size and so leads to better construction and manufacturing cost performance for prototype. The draft tube geometry parameter designing process was concerning the best efficiency point together with the off-design points covering various water net heads and discharges. The hydraulic performance and flow behavior was numerically previewed and visualized by solving Reynolds-Averaged Navier-Stokes equations with Shear Stress Transport turbulence model. The simulation was under the assumption of steady-state incompressible turbulence flow inside the flow passage, and the inlet boundary condition was the carefully simulated flow pattern from the runner outlet. For confirmation, the corresponding turbine efficiency performance of the entire operating area was verified by model test.

  1. Construction and test of new precision drift-tube chambers for the ATLAS muon spectrometer

    Energy Technology Data Exchange (ETDEWEB)

    Kroha, H., E-mail: kroha@mpp.mpg.de; Kortner, O.; Schmidt-Sommerfeld, K.; Takasugi, E.

    2017-02-11

    ATLAS muon detector upgrades aim for increased acceptance for muon triggering and precision tracking and for improved rate capability of the muon chambers in the high-background regions of the detector with increasing LHC luminosity. The small-diameter Muon Drift Tube (sMDT) chambers have been developed for these purposes. With half of the drift-tube diameter of the MDT chambers and otherwise unchanged operating parameters, sMDT chambers share the advantages of the MDTs, but have an order of magnitude higher rate capability and can be installed in detector regions where MDT chambers do not fit in. The chamber assembly methods have been optimized for mass production, minimizing construction time and personnel. Sense wire positioning accuracies of 5 μm have been achieved in serial production for large-size chambers comprising several hundred drift tubes. The construction of new sMDT chambers for installation in the 2016/17 winter shutdown of the LHC and the design of sMDT chambers in combination with new RPC trigger chambers for replacement of the inner layer of the barrel muon spectrometer are in progress.

  2. Construction and test of new precision drift-tube chambers for the ATLAS muon spectrometer

    Science.gov (United States)

    Kroha, H.; Kortner, O.; Schmidt-Sommerfeld, K.; Takasugi, E.

    2017-02-01

    ATLAS muon detector upgrades aim for increased acceptance for muon triggering and precision tracking and for improved rate capability of the muon chambers in the high-background regions of the detector with increasing LHC luminosity. The small-diameter Muon Drift Tube (sMDT) chambers have been developed for these purposes. With half of the drift-tube diameter of the MDT chambers and otherwise unchanged operating parameters, sMDT chambers share the advantages of the MDTs, but have an order of magnitude higher rate capability and can be installed in detector regions where MDT chambers do not fit in. The chamber assembly methods have been optimized for mass production, minimizing construction time and personnel. Sense wire positioning accuracies of 5 μm have been achieved in serial production for large-size chambers comprising several hundred drift tubes. The construction of new sMDT chambers for installation in the 2016/17 winter shutdown of the LHC and the design of sMDT chambers in combination with new RPC trigger chambers for replacement of the inner layer of the barrel muon spectrometer are in progress.

  3. Construction and Test of New Precision Drift-Tube Chambers for the ATLAS Muon Spectrometer

    CERN Document Server

    INSPIRE-00218480

    2017-02-11

    ATLAS muon detector upgrades aim for increased acceptance for muon triggering and precision tracking and for improved rate capability of the muon chambers in the high-background regions of the detector with increasing LHC luminosity. The small-diameter Muon Drift Tube (sMDT) chambers have been developed for these purposes. With half of the drift-tube diameter of the MDT chambers and otherwise unchanged operating parameters, sMDT chambers share the advantages of the MDTs, but have an order of magnitude higher rate capability and can be installed in detector regions where MDT chambers do not fit in. The chamber assembly methods have been optimized for mass production, minimizing construction time and personnel. Sense wire positioning accuracies of 5 ?micons have been achieved in serial production for large-size chambers comprising several hundred drift tubes. The construction of new sMDT chambers for installation in the 2016/17 winter shutdown of the LHC and the design of sMDT chambers in combination with new R...

  4. A Study on the Small Punch Test for Fracture Strength Evaluation of CANDU Pressure Tube Embrittled by Hydrogen

    International Nuclear Information System (INIS)

    Nho, Seung Hwan; Ong, Jang Woo; Yu, Hyo Sun; Chung, Se Hi

    1996-01-01

    The purpose of this study is to investigate the usefulness of small punch(SP) test using miniaturized specimens as a method for fracture strength evaluation of CANDU pressure tube embrittled by hydrogen. According to the test results, the fracture strength evaluation as a function of hydrogen concentration at -196 .deg. C was much better than that at room temperature, as the difference of SP fracture energy(Esp) with hydrogen concentration was more significant at -196 .deg. C than at room temperature for the hydrogen concentration up to 300ppm-H. It was also observed that the peak of average AE energy, the cumulative average AE energy and the cumulative average AE energy per equivalent fracture, strain increased with the increase of hydrogen concentration. From the results of load-displacement behaviors, Esp behaviors, macro- and micro-SEM fractographs and AE test it has been concluded that the SP test method using miniaturized specimen(10mmx10mmx0.5mm) will be a useful test method to evaluate the fracture strength for CANDU pressure tube embrittled by hydrogen

  5. Development of Micro-welding Technology of Cladding Tube with Temperature Sensor for Nuclear Fuel Irradiation Test

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Soo Sung; Lee, C. Y.; Kim, W. K.; Lee, J. W.; Lee, D. Y

    2006-01-15

    Laser welding technology is widely used to fabricate some products of nuclear fuel in the nuclear industry. Especially, micro-laser welding is one of the key technology to be developed to fabricate precise products of fuel irradiation test. We have to secure laser welding technology to perform various instrumentations for fuel irradiation test. The instrumented fuel irradiation test at a research reactor is needed to evaluate the performance of the developed nuclear fuel. The fuel elements can be designed to measure the center line temperature of fuel pellets during the irradiation test by using temperature sensor. The thermal sensor was composed of thermocouple and sensor sheath. Micro-laser welding technology was adopted to seal between seal tube and sensor sheath with thickness of 0.15mm. The soundness of weld area has to be confirmed to prevent fission gas of the fuel from leaking out of the element during the fuel irradiation test. In this study, fundamental data for micro-laser welding technology was proposed to seal temperature sensor sheath of the instrumented fuel element. And, micro-laser welding for dissimilar metals between sensor sheath and seal tube was characterized by investigating welding conditions. Moreover, the micro-laser welding technology is closely related to advanced industry. It is expected that the laser material processing technology will be adopted to various applications in the industry.

  6. A flow test for calibrating 177 core tubes of 1/5-scale reactor flow model for Yonggwang nuclear units 3 and 4

    International Nuclear Information System (INIS)

    Lee, Byung Jin; Jang, Ho Cheol; Cheong, Jong Sik; Kuh, Jung Eui

    1990-01-01

    A flow test was performed to find out the hydraulic characteristics of every one of 177 core tubes, representing a fuel assembly respectively, as a preparatory step of 1/5 scale reactor flow model test for Yonggwang Nuclear Units (hereafter YGN) 3 and 4. The axial hydraulic resistance of the fuel assembly was simulated in the square core tube with six orifice plates positioned along the tube length; core support structure below each fuel assembly was done in the core upstream geometry section of the test loop. For each core tube the pressure differentials across the inlet, exit orifice plate and overall tube length were measured, along with the flow rates and temperatures of the test fluid. The measured pressure drops were converted to pressure loss or flow metering coefficients. The metering coefficient of the inlet orifice plate was sensitive to the configuration and location of the upstream geometry. The hydraulic resistance of the core tubes were reasonably coincided with a target value and consistent. The polynomial curve fits of the calibrated coefficients for the 177 core tubes were obtained with reasonable data scatters

  7. Effect of smoke derivatives on in vitro pollen germination and pollen tube elongation of species from different plant families

    Czech Academy of Sciences Publication Activity Database

    Kumari, A.; Papenfus, H. B.; Kulkarni, M. G.; Pošta, Martin; van Staden, J.

    2015-01-01

    Roč. 17, č. 4 (2015), s. 825-830 ISSN 1435-8603 Institutional support: RVO:61388963 Keywords : karrikinolide * pollen germination * pollen tube growth * smoke-water * trimethylbutenolide Subject RIV: CC - Organic Chemistry Impact factor: 2.216, year: 2015

  8. Scramjet test flow reconstruction for a large-scale expansion tube, Part 1: quasi-one-dimensional modelling

    Science.gov (United States)

    Gildfind, D. E.; Jacobs, P. A.; Morgan, R. G.; Chan, W. Y. K.; Gollan, R. J.

    2017-11-01

    Large-scale free-piston driven expansion tubes have uniquely high total pressure capabilities which make them an important resource for development of access-to-space scramjet engine technology. However, many aspects of their operation are complex, and their test flows are fundamentally unsteady and difficult to measure. While computational fluid dynamics methods provide an important tool for quantifying these flows, these calculations become very expensive with increasing facility size and therefore have to be carefully constructed to ensure sufficient accuracy is achieved within feasible computational times. This study examines modelling strategies for a Mach 10 scramjet test condition developed for The University of Queensland's X3 facility. The present paper outlines the challenges associated with test flow reconstruction, describes the experimental set-up for the X3 experiments, and then details the development of an experimentally tuned quasi-one-dimensional CFD model of the full facility. The 1-D model, which accurately captures longitudinal wave processes, is used to calculate the transient flow history in the shock tube. This becomes the inflow to a higher-fidelity 2-D axisymmetric simulation of the downstream facility, detailed in the Part 2 companion paper, leading to a validated, fully defined nozzle exit test flow.

  9. Scramjet test flow reconstruction for a large-scale expansion tube, Part 1: quasi-one-dimensional modelling

    Science.gov (United States)

    Gildfind, D. E.; Jacobs, P. A.; Morgan, R. G.; Chan, W. Y. K.; Gollan, R. J.

    2018-07-01

    Large-scale free-piston driven expansion tubes have uniquely high total pressure capabilities which make them an important resource for development of access-to-space scramjet engine technology. However, many aspects of their operation are complex, and their test flows are fundamentally unsteady and difficult to measure. While computational fluid dynamics methods provide an important tool for quantifying these flows, these calculations become very expensive with increasing facility size and therefore have to be carefully constructed to ensure sufficient accuracy is achieved within feasible computational times. This study examines modelling strategies for a Mach 10 scramjet test condition developed for The University of Queensland's X3 facility. The present paper outlines the challenges associated with test flow reconstruction, describes the experimental set-up for the X3 experiments, and then details the development of an experimentally tuned quasi-one-dimensional CFD model of the full facility. The 1-D model, which accurately captures longitudinal wave processes, is used to calculate the transient flow history in the shock tube. This becomes the inflow to a higher-fidelity 2-D axisymmetric simulation of the downstream facility, detailed in the Part 2 companion paper, leading to a validated, fully defined nozzle exit test flow.

  10. Characteristics Testing of the ECT Bobbin Probe for S/G Tube Inspection

    Energy Technology Data Exchange (ETDEWEB)

    Nam, Min Woo; Lee, Hee Jong; Cho, Chan Hee; Yoo, Hyun Joo [Korea Electric Power Research Institute, Daejeon (Korea, Republic of)

    2010-05-15

    The bobbin probe technique is basically one of the important ECT methods for the steam generator tube integrity assessment that is practiced during each plant outage. The bobbin probe also is the essential component which consists of the whole ECT examination system, and provides a decisive data for the evaluation of tube integrity in compliance with acceptance criteria described in specific procedures. The selection of probe is especially important because the quality of acquired ECT data is determined by the probe design characteristics, such as geometry and operation frequency, and has an important effect on examination results. The Electric Power Research Institute (EPRI) has recently defined the procedures for the qualification of eddy current hardware and technique. These procedures provide two basic methods for qualification. Flawed tube removed from operation, or artificial flaw is required for the original qualification of technique combined with related flaw mechanism. In case where the original qualification has been completed, the concept of equivalency may be used to extend the original qualification to similar probe designs. The qualified acquisition technique may be modified to substitute or replace instruments or probes without re-qualification provided that the range of essential variables defined in the examination technique specification sheet are met. In this case, both the original and replaced instrument or probe shall be characterized utilizing EPRI Guideline supplement 'H1'. This study is the result of the comparative performance evaluation of bobbin coil eddy current probes manufactured by KEPRI and a foreign manufacturer. As a result of this study, although there were minor differences between the two probe types, it was evaluated that the two probes were almost identical in the significant performance characteristics described in the EPRI guideline

  11. Coaxial guiding assembly for internal through-passing probe for eddy current testing of tubes

    International Nuclear Information System (INIS)

    Kubis, S.; Holec, P.

    1989-01-01

    The device features guiding cases mounted on springs provided on the peripheries with two rows of radial openings into which are wound flexible fibres parallel with the case axis. The advantage of the design is that active elements which provide the coaxial guiding of the probe are oriented in the direction of the probe movement. This significantly reduces friction between the probe and the internal wall of the tube and thereby also wear of the guide parts of the probe. (J.B.). 2 figs

  12. Laboratory evaluation of the improved tube test detection limits for β ...

    African Journals Online (AJOL)

    Administrator

    1Antibiotic research laboratory, Dept. of Food Science, Swedish University of Agricultural Sciences, P.O. Box 7051, S- ... particular commonly utilised in lactating animals (Mandell and Perti ..... for other families of drugs such as sulfa drugs,.

  13. Characteristics Testing of the ECT Bobbin Probe for Steam Generator Tube Inspection of Nuclear Power Plant

    International Nuclear Information System (INIS)

    Nam, Min Woo; Lee, Hee Jong; Cho, Chan hee; Yoo, Hyun Joo

    2010-01-01

    The steam generator management program(SGMP) has recently defined the procedures for the qualification of eddy current hardware and technique. These procedures provide two basic methods for qualification. The first way is to qualify the equipment or the probe by using the flaw mechanism and method of the pulled tubes from the heat exchangers or the artificial flawed tubes. The second way is to verify the equivalency with the characteristics of the qualified equipment or probe. In this case, the qualified equipment or probe may be modified to substitute or replace instruments or probes without re-qualification provided that the range of essential variables defined in the examination technique specification sheet are met. This study is to describe the result of the comparative performance evaluation of bobbin coil eddy current probes manufactured by KEPCO Research Institute and probes manufactured by a foreign manufacturer. As a result of this study, although there were minor differences between the two kinds of probes, it was evaluated that the two kinds of probes were almost identical in the significant performance characteristics described in the KEPCO Research Institute guideline

  14. Characteristics Testing of the ECT Bobbin Probe for Steam Generator Tube Inspection of Nuclear Power Plant

    Energy Technology Data Exchange (ETDEWEB)

    Nam, Min Woo; Lee, Hee Jong; Cho, Chan hee; Yoo, Hyun Joo [KEPCO, Daejeon (Korea, Republic of)

    2010-08-15

    The steam generator management program(SGMP) has recently defined the procedures for the qualification of eddy current hardware and technique. These procedures provide two basic methods for qualification. The first way is to qualify the equipment or the probe by using the flaw mechanism and method of the pulled tubes from the heat exchangers or the artificial flawed tubes. The second way is to verify the equivalency with the characteristics of the qualified equipment or probe. In this case, the qualified equipment or probe may be modified to substitute or replace instruments or probes without re-qualification provided that the range of essential variables defined in the examination technique specification sheet are met. This study is to describe the result of the comparative performance evaluation of bobbin coil eddy current probes manufactured by KEPCO Research Institute and probes manufactured by a foreign manufacturer. As a result of this study, although there were minor differences between the two kinds of probes, it was evaluated that the two kinds of probes were almost identical in the significant performance characteristics described in the KEPCO Research Institute guideline

  15. Comparative experiments for tube agglutination test of pullorum antiserum with gamma ray Co/sup 60/ irradiated salmonella pullorum

    Energy Technology Data Exchange (ETDEWEB)

    Seo, B K [City Univ. of Seoul, Seoul (Republic of Korea)

    1976-01-01

    An agglutinability between naturally infected positive chicken serum of pullorum disease and hyperimmunized rabbit antiserum was compared. And the following results were obtained and summarized. On the agglutinability, Salmonella pullorum antigen which irradiated gamma-ray was better than another both formalized and heated antigen. Time of judgemented as positive titer in the tube agglutination test to the naturally infected positive chicken serum was it most suitable for 12 hours at 37/sup 0/C. Agglutination titer of positive immune chicken serum against gamma-ray irradiate Salmonella pullorum were as 320 approximately 640x.

  16. Performance test results of mock-up model test facility with a full-scale reaction tube for HTTR hydrogen production system. Contract research

    Energy Technology Data Exchange (ETDEWEB)

    Inagaki, Yoshiyuki; Hayashi, Koji; Kato, Michio [Japan Atomic Energy Research Inst., Oarai, Ibaraki (Japan). Oarai Research Establishment] [and others

    2003-03-01

    Research on a hydrogen production system by steam reforming of methane, chemical reaction; CH{sub 4} + H{sub 2}O {yields} 3H{sub 2}O + CO, has been carried out to couple with the HTTR for establishment of high-temperature nuclear heat utilization technology and contribution to hydrogen energy society in future. The mock-up test facility with a full-scale reaction tube test facility, a model simulating one reaction tube of a steam reformer of the HTTR hydrogen production system in full scale, was fabricated to perform tests on controllability, hydrogen production performance etc. under the same pressure and temperature conditions as those of the HTTR hydrogen production system. The design and fabrication of the test facility started from 1997, and the all components were installed until September in 2001. In a performance test conducted from October in 2001 to February in 2002, performance of each component was examined and hydrogen of 120m{sup 3}{sub N}/h was successfully produced with high-temperature helium gas. This report describes the performance test results on components performance, hydrogen production characteristics etc., and main troubles and countermeasures. (author)

  17. Performance test results of mock-up model test facility with a full-scale reaction tube for HTTR hydrogen production system. Contract research

    International Nuclear Information System (INIS)

    Inagaki, Yoshiyuki; Hayashi, Koji; Kato, Michio

    2003-03-01

    Research on a hydrogen production system by steam reforming of methane, chemical reaction; CH 4 + H 2 O → 3H 2 O + CO, has been carried out to couple with the HTTR for establishment of high-temperature nuclear heat utilization technology and contribution to hydrogen energy society in future. The mock-up test facility with a full-scale reaction tube test facility, a model simulating one reaction tube of a steam reformer of the HTTR hydrogen production system in full scale, was fabricated to perform tests on controllability, hydrogen production performance etc. under the same pressure and temperature conditions as those of the HTTR hydrogen production system. The design and fabrication of the test facility started from 1997, and the all components were installed until September in 2001. In a performance test conducted from October in 2001 to February in 2002, performance of each component was examined and hydrogen of 120m 3 N /h was successfully produced with high-temperature helium gas. This report describes the performance test results on components performance, hydrogen production characteristics etc., and main troubles and countermeasures. (author)

  18. Inversion of lithium heparin gel tubes after centrifugation is a significant source of bias in clinical chemistry testing.

    Science.gov (United States)

    Lippi, Giuseppe; Salvagno, Gian Luca; Danese, Elisa; Lima-Oliveira, Gabriel; Brocco, Giorgio; Guidi, Gian Cesare

    2014-09-25

    This study was planned to establish whether random orientation of gel tubes after centrifugation may impair sample quality. Eight gel tubes were collected from 17 volunteers: 2 Becton Dickinson (BD) serum tubes, 2 Terumo serum tubes, 2 BD lithium heparin tubes and 2 Terumo lithium heparin tubes. One patient's tube for each category was kept in a vertical, closure-up position for 90 min ("upright"), whereas paired tubes underwent bottom-up inversion every 15 min, for 90 min ("inverted"). Immediately after this period of time, 14 clinical chemistry analytes, serum indices and complete blood count were then assessed in all tubes. Significant increases were found for phosphate and lipaemic index in all inverted tubes, along with AST, calcium, cholesterol, LDH, potassium, hemolysis index, leukocytes, erythrocytes and platelets limited to lithium heparin tubes. The desirable quality specifications were exceeded for AST, LDH, and potassium in inverted lithium heparin tubes. Residual leukocytes, erythrocytes, platelets and cellular debris were also significantly increased in inverted lithium heparin tubes. Lithium heparin gel tubes should be maintained in a vertical, closure-up position after centrifugation. Copyright © 2014 Elsevier B.V. All rights reserved.

  19. Thin walled Nb tubes for suspending test masses in interferometric gravitational wave detectors

    Energy Technology Data Exchange (ETDEWEB)

    Lee, B.H. [School of Physics, University of Western Australia, Crawley 6009, WA (Australia)]. E-mail: bhl@physics.uwa.edu.au; Ju, L. [School of Physics, University of Western Australia, Crawley 6009, WA (Australia); Blair, D.G. [School of Physics, University of Western Australia, Crawley 6009, WA (Australia)

    2006-02-13

    In a previous Letter, we have shown that the use of orthogonal ribbons could provide a better mirror suspension technique in interferometric gravitational wave antennas. One of the key improvements presented by the orthogonal ribbon is the reduction in the number of violin string modes in the direction of the laser. We have considered more elaborate geometries in recent simulations and obtained a suspension that provides further reduction in the number of violin string modes in the direction of the laser, as well as in the direction orthogonal to the laser. This thin walled niobium tube suspension exhibits a reduction in the number of violin modes to 5 in each direction up to a frequency of 5 kHz. Furthermore, the violin mode thermal noise peaks can be reduced in amplitude by 30 dB.

  20. Thin walled Nb tubes for suspending test masses in interferometric gravitational wave detectors

    International Nuclear Information System (INIS)

    Lee, B.H.; Ju, L.; Blair, D.G.

    2006-01-01

    In a previous Letter, we have shown that the use of orthogonal ribbons could provide a better mirror suspension technique in interferometric gravitational wave antennas. One of the key improvements presented by the orthogonal ribbon is the reduction in the number of violin string modes in the direction of the laser. We have considered more elaborate geometries in recent simulations and obtained a suspension that provides further reduction in the number of violin string modes in the direction of the laser, as well as in the direction orthogonal to the laser. This thin walled niobium tube suspension exhibits a reduction in the number of violin modes to 5 in each direction up to a frequency of 5 kHz. Furthermore, the violin mode thermal noise peaks can be reduced in amplitude by 30 dB

  1. Mechanical design, fabrication and initial tests on prototype drift tube linac at IUAC

    International Nuclear Information System (INIS)

    Sacharias, J.; Mehta, R.; Hariwal, R.V.; Ajithkumar, B.P.

    2011-01-01

    The Drift Tube Linac (DTL) project is a major subsection of High Current Injector project at Inter University Accelerator Centre (IUAC). It has been designed to accelerate ions from 180 keV/u to 1.8 MeV/u, using six IH type RF resonators operating at 97 MHz. The required output energy of the DTL is decided by the minimum input velocity of nearly 6% of velocity of light, required for the existing superconducting LINAC. IH type resonators are the preferred choice for multiple gap DTL applications due to their high shunt impedance values. The mechanical design and CNC machining of parts and assembly of DTL were carried out at IUAC to validate the electrical design. (author)

  2. Test of multi-anode photomultiplier tubes for the LHCb scintillator pad detector

    CERN Document Server

    Aguiló, Ernest; Comerma-Montells, A; Garrido, Lluis; Gascon, David; Graciani, Ricardo; Grauges, Eugeni; Vilasis Cardona, Xavier; Xirgu, Xavier; Bohner, Gerard; Bonnefoy, Romeo; Borras, David; Cornat, Remi; Crouau, Michel; Deschamps, Olivier; Jacquet, Philippe; Lecoq, Jacques; Monteil, Stephane; Perret, Pascal; Reinmuth, Guy

    2005-01-01

    The LHCb experiment (The LHCb Technical Proposal, CERN/LHCC 98-4) is designed to study B meson physics in the LHC proton-proton collider at CERN. The Scintillator Pad Detector (SPD) has been designed to complete the calorimeter information performing an e/gamma identification for the experiment level-0 trigger system. The detection technology consists in transmitting scintillation light by means of both Wavelength Shifting and clear fibers to fast multi- anode photomultiplier tubes. In this paper, it is described the instrumentation and setup used to characterize the baseline photomultiplier solution (Hamamatsu R5900-00-M64) together with the scintillators and optical fibers for the SPD at LHCb.

  3. Predicting crack instability behavior of burst tests from small specimens for irradiated Zr-2.5Nb pressure tubes

    International Nuclear Information System (INIS)

    Davies, P.H.

    1997-01-01

    A scaling approach, based on the deformation J-integral at maximum load obtained from small specimens, is proposed for predicting the crack instability behavior of burst tests on irradiated Zr-2.5Nb pressure tubes. An assessment of this approach is carried out by comparison with other toughness criteria such as the modified J-integral and the plastic work dissipation rate approach. The largest discrepancy between the different parameters occurs for materials of intermediate toughness which exhibit the most stable crack growth and tunnelling up to maximum load. A study of one material of intermediate toughness suggests crack-front tunnelling has a significant influence on the results obtained from the 17-mm-wide specimens. It is shown that for a tube of intermediate toughness the different approaches can significantly underpredict the extent of stable crack growth before instability in a burst test even after correcting for tunnelling. The usefulness of a scaling approach in reducing the discrepancy between the small- and large-scale specimen results for this material is demonstrated

  4. Influence of pH on organic acid production by Clostridium sporogenes in test tube and fermentor cultures.

    Science.gov (United States)

    Montville, T J; Parris, N; Conway, L K

    1985-01-01

    The influence of pH on the growth parameters of and the organic acids produced by Clostridium sporogenes 3121 cultured in test tubes and fermentors at 35 degrees C was examined. Specific growth rates in the fermentor maintained at a constant pH ranged from 0.20 h-1 at pH 5.00 to 0.86 h-1 at pH 6.50. Acetic acid was the primary organic acid in supernatants of 24-h cultures; total organic acid levels were 2.0 to 22.0 mumol/ml. Supernatants from pH 5.00 and 5.50 cultures had total organic acid levels less than one-third of those found at pH 6.00 to 7.00. The specific growth rates of the test tube cultures ranged from 0.51 h-1 at pH 5.00 to 0.95 h-1 at pH 6.50. The pH of the medium did not affect the average total organic acid content (51.5 mumol/ml) but did affect the distribution of the organic acids, which included formic, acetic, propionic, butyric, 3-(p-hydroxyphenyl)propionic, and 3-phenylpropionic acids. Butyric acid levels were lower, but formic and propionic acid levels were higher, at pH 5.00 than at other pHs. PMID:4004207

  5. Ultrasonic testing of canning tubes in stainless steel of the EL 4 reactor; Controle par ultrasons des tubes de gaine en acier inoxydable du reacteur EL 4

    Energy Technology Data Exchange (ETDEWEB)

    Prot, A; Monnier, P [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1964-07-01

    From all the methods possible for controlling thin cans the one chosen, for numerous reasons, vas that making use of ultrasonic techniques. A method has been developed which should make it possible to carry out a rapid and efficient industrial control of canning tubes, The reasons for the choice of the ultrasonic method are given in detail, together with the principles of the method and the actual control parameters. In the present state of our research, it should be possible to control at least 50 000 tubes a year. Improvements brought about in the details of the control technique itself should make it possible to increase this rate considerably. (authors) [French] Parmi toutes les methodes possibles de controle des gaines minces, le procede retenu pour de multiples raisons a ete celui faisant appel a la technique des ultrasons. Une methode a ete mise au point qui doit permettre un controle industriel rapide et efficace des tubes de gaine. Sont exposes en detail, les raisons du choix de la methode par ultrasons, les principes de cette methode et les parametres du controle proprement dit. Dans l'etat actuel de nos etudes la cadence devrait permettre le controle de 50000 tubes par an au minimum. Des ameliorations de detail portant sur la technique de controle elle-meme, doivent permettre d'accelerer tres notablement cette cadence. (auteurs)

  6. Evaluation of the educational technology "Caring for dependent people" by family caregivers in changes and transfers of patients and tube feeding

    Directory of Open Access Journals (Sweden)

    Maria José Lumini Landeiro

    Full Text Available ABSTRACT Objective: to assess the contributions of interactive educational technology "Caring for Dependent People" in the development of knowledge to family caregivers of dependent people in a household context and their satisfaction in its use. Method: quasi-experimental study, not randomized, of the before and after type, with a convenience sample of 65 family caregivers, from two Medicine services of a hospital in Porto, Portugal. The Control Group consisted of 33 family caregivers and the Experimental Group of 32, identified by consecutive sampling. The experimental group had access to educational technology at home. Data were collected by socio-demographic, satisfaction and evaluation of knowledge questionnaire, about how to feed by nasogastric tube, positioning and transferring the dependent person. The assessment in both groups had two moments: initial, during hospitalization and one month after discharge. Results: the experimental group had a larger increase in knowledge related to the use of the educational technology. In the control group the knowledge did not differ in the two evaluation time points. Conclusion: these results confirm the improvement of interactive educational technologies and in the training of family caregivers to care for dependents. This technology successfully met the technical quality and learning needs of caregivers, and was considered easy and stimulating.

  7. Reduction of residual stresses in internal skin of transient zones of PWR steam generator expanded tubes: tests with a ''rotating brush''

    International Nuclear Information System (INIS)

    Vidal, P.

    1984-04-01

    A process aiming at preventing or suppressing cracks under stress corrosion on the primary side in the expanded zones of PWR steam generator tubes has been studied; it consists in hammering the internal skin of tubes in these zones what reduces the level of residual expanding stresses to lower values around 100-150 MPa without modifying the stress level in external skin. Tests in magnesium chloride to estimate the residual stresses of tubes in low carbon stainless austenitic steel 18% Cr-12% Ni with molybdene [fr

  8. Definition of the minimum longitude of insert in the rebuilding of Charpy test tubes for surveillance and life extension of vessels in Mexico

    International Nuclear Information System (INIS)

    Romero C, J.; Hernandez C, R.; Rocamontes A, M.

    2011-11-01

    In the National Institute of Nuclear Research (Mexico) a welding system for the rebuilding of Charpy test tubes has been developed, automated, qualified and used for the surveillance of the mechanical properties (mainly embrittlement) of the vessel. This system uses the halves of the rehearsed Charpy test tubes of the surveillance capsules extracted of the reactors, to obtain, of a rehearsed test tube, two reconstituted test tubes. This rebuilding process is used so much in the surveillance program like in the potential extension of the operation license of the vessel. To the halves of Charpy test tubes that have been removed the deformed part by machine are called -insert- and in a very general way the rebuilding consists in weld with the welding process -Stud Welding- two metallic implants in the ends of the insert, to obtain a reconstituted test tube. The main characteristic of this welding are the achieved small dimensions, so much of the areas welded as of the areas affected by the heat. The applicable normative settles down that the minim longitude of the insert for the welding process by Stud Welding it should be of 18 mm, however according to the same normative this longitude can diminish if is demonstrated analytic or experimentally that the central volume of 1 cm 3 in the insert is not affected. In this work the measurement of the temperature profiles to different distances of the welding interface is presented, defining an equation for the maximum temperatures reached in function of the distance, on the other hand the real longitude affected in the test tube by means of metallography is determined and this way the minimum longitude of the insert for this developed rebuilding system was determined. (Author)

  9. Putting theory to the test: Examining family context, caregiver motivation, and conflict in the Family Check-Up model

    Science.gov (United States)

    Fosco, Gregory M.; Van Ryzin, Mark; Stormshak, Elizabeth A.; Dishion, Thomas J.

    2014-01-01

    This study examined contextual factors (caregiver depression, family resources, ethnicity, and initial levels of youth problem behavior) related to the effectiveness of the Family Check-Up (FCU) and evaluated family processes as a mediator of FCU intervention response and adolescent antisocial behavior. We followed a sample of 180 ethnically diverse youths of families who engaged in the FCU intervention. Family data were collected as part of the FCU assessment, and youth data were collected over 4 years, from sixth through ninth grade. Findings indicated that caregiver depression and minority status predicted greater caregiver motivation to change. In turn, caregiver motivation was the only direct predictor of FCU intervention response during a 1-year period. Growth in family conflict from sixth through eighth grade mediated the link between FCU response and ninth-grade antisocial behavior. This study explicitly tested core aspects of the FCU intervention model and demonstrated that caregiver motivation is a central factor that underlies family response to the FCU. The study also provided support for continued examination of family process mechanisms that account for enduring effects of the FCU and other family-centered interventions. PMID:24438894

  10. Putting theory to the test: examining family context, caregiver motivation, and conflict in the Family Check-Up model.

    Science.gov (United States)

    Fosco, Gregory M; Van Ryzin, Mark; Stormshak, Elizabeth A; Dishion, Thomas J

    2014-05-01

    This study examined contextual factors (caregiver depression, family resources, ethnicity, and initial levels of youth problem behavior) related to the effectiveness of the Family Check-Up (FCU) and evaluated family processes as a mediator of FCU intervention response and adolescent antisocial behavior. We followed a sample of 180 ethnically diverse youths of families who engaged in the FCU intervention. Family data were collected as part of the FCU assessment, and youth data were collected over 4 years, from sixth through ninth grade. Findings indicated that caregiver depression and minority status predicted greater caregiver motivation to change. In turn, caregiver motivation was the only direct predictor of FCU intervention response during a 1-year period. Growth in family conflict from sixth through eighth grade mediated the link between FCU response and ninth-grade antisocial behavior. This study explicitly tested core aspects of the FCU intervention model and demonstrated that caregiver motivation is a central factor that underlies family response to the FCU. The study also provided support for continued examination of family process mechanisms that account for enduring effects of the FCU and other family-centered interventions.

  11. Construction and Test of Muon Drift Tube Chambers for High Counting Rates

    CERN Document Server

    Schwegler, Philipp; Dubbert, Jörg

    2010-01-01

    Since the start of operation of the Large Hadron Collider (LHC) at CERN on 20 November 2009, the instantaneous luminosity is steadily increasing. The muon spectrometer of the ATLAS detector at the LHC is instrumented with trigger and precision tracking chambers in a toroidal magnetic field. Monitored Drift-Tube (MDT) chambers are employed as precision tracking chambers, complemented by Cathode Strip Chambers (CSC) in the very forward region where the background counting rate due to neutrons and γ's produced in shielding material and detector components is too high for the MDT chambers. After several upgrades of the CERN accelerator system over the coming decade, the instantaneous luminosity is expected to be raised to about five times the LHC design luminosity. This necessitates replacement of the muon chambers in the regions with the highest background radiation rates in the so-called Small Wheels, which constitute the innermost layers of the muon spectrometer end-caps, by new detectors with higher rate cap...

  12. Results from integral tests of single reformer tubes under simulated nuclear reactor conditions

    International Nuclear Information System (INIS)

    Decken, C.B. von der; Fedders, H.; Harth, R.; Hoehlein, B.; Riensche, E.

    1980-01-01

    The possibility of supplying high temperature heat from a HTGR for process application is being investigated at some places in the world. In all programmes or projects existing with respect to this application, the endothermic steam reforming of methane is one main step in the transmission of heat produced by nuclear fission to different chemical processes. The KFA is involved in the two German projects PNP - Prototypanlage Nukleare Prozesswaerme (Prototype-plant Nuclear Process-heat), and NFE -Nukleare Fernenergie (Long Distance Energy Transport). In a HTGR, helium generally serves as reactor coolant. It transports the heat from the core to the different components which take over this heat for various purposes. In case of arranging a steam reformer in the helium circuit, it is necessary for economic reasons to reach very high temperatures. In the two German projects mentioned above, the helium temperature at HTGR core outlet is determined to 950 0 C. Thus the main design data for a steam reformer supplied by heat from a HTGR are maximum helium temperature 950 0 C, helium pressure 40 bar. By an extensive utilization of the available advanced conventional steam reforming technology, the helium heated steam reformer design is using normal steam reforming tubes arranged in compact bundles

  13. Single cells for forensic DNA analysis--from evidence material to test tube.

    Science.gov (United States)

    Brück, Simon; Evers, Heidrun; Heidorn, Frank; Müller, Ute; Kilper, Roland; Verhoff, Marcel A

    2011-01-01

    The purpose of this project was to develop a method that, while providing morphological quality control, allows single cells to be obtained from the surfaces of various evidence materials and be made available for DNA analysis in cases where only small amounts of cell material are present or where only mixed traces are found. With the SteREO Lumar.V12 stereomicroscope and UV unit from Zeiss, it was possible to detect and assess single epithelial cells on the surfaces of various objects (e.g., glass, plastic, metal). A digitally operated micromanipulator developed by aura optik was used to lift a single cell from the surface of evidence material and to transfer it to a conventional PCR tube or to an AmpliGrid(®) from Advalytix. The actual lifting of the cells was performed with microglobes that acted as carriers. The microglobes were held with microtweezers and were transferred to the DNA analysis receptacles along with the adhering cells. In a next step, the PCR can be carried out in this receptacle without removing the microglobe. Our method allows a single cell to be isolated directly from evidence material and be made available for forensic DNA analysis. © 2010 American Academy of Forensic Sciences.

  14. Comparison of the Effects of using Tygon Tubing in Rocket Propulsion Ground Test Pressure Transducer Measurements

    Science.gov (United States)

    Farr, Rebecca A.; Wiley, John T.; Vitarius, Patrick

    2005-01-01

    This paper documents acoustics environments data collected during liquid oxygen- ethanol hot-fire rocket testing at NASA Marshall Space Flight Center in November- December 2003. The test program was conducted during development testing of the RS-88 development engine thrust chamber assembly in support of the Orbital Space Plane Crew Escape System Propulsion Program Pad Abort Demonstrator. In addition to induced environments analysis support, coincident data collected using other sensors and methods has allowed benchmarking of specific acoustics test measurement methodologies during propulsion tests. Qualitative effects on data characteristics caused by using tygon sense lines of various lengths in pressure transducer measurements is discussed here.

  15. Corrosion evaluation of heat recovery steam generator superheater tube in two methods of testing: Tafel polarization and electrochemical impedance spectroscopy (EIS)

    Science.gov (United States)

    Santoso, Rio Pudjidarma; Riastuti, Rini

    2018-05-01

    The purpose of this research is to evaluate the corrosion process which occurs on the water side of Heat Recovery Steam Generator (HRSG) superheater tube. The tube was 13CrMo44 and divided into 3 types of specimen: new tube, used tube (with oxide layer on surface), cleaned-used tube (without oxide layer on surface). The evaluation of corrosion parameters wasperformed using deaerated ultra-high purity water (boiler feed water) in two methods of testing: Tafel polarization and Electrochemical Impedance Spectroscopy (EIS). Tafel polarization was excellent as its capability to show the value of corrosion current and the corrosion rate explicitly, on the other hand, EIS was excellent as its capability to explain for corrosion mechanism on metal interface in detail. Both methods showed that the increase of electrolyte temperature from 25°C to 55°C would increase the corrosion rate with the mechanism of decreasing polarization resistance due to thinning out the passive film thickness and enlarge the area of reduction reaction of cathode. Magnetite oxide scale which is laid on the surface of used tube specimen shows protective nature to reduce the corrosion rate, and clear up this oxide would increase the corrosion rate back as new tube.

  16. Design and microwave test of an ultrawideband input/output structure for sheet beam travelling wave tubes

    International Nuclear Information System (INIS)

    Shu, Guoxiang; Wang, Jianxun; Liu, Guo; Yang, Liya; Luo, Yong; Wang, Shafei

    2015-01-01

    Broadband operation is of great importance for the applications of travelling wave tubes such as high-data communication and wideband radar. An input/output (I/O) structure operating with broadband property plays a significant role to achieve these applications. In this paper, a Y-type branch waveguide (YTBW) coupler and its improvements are proposed and utilized to construct an extremely wideband I/O structure to ensure the broadband operation for sheet beam travelling wave tubes (SB-TWTs). Cascaded reflection resonators are utilized to improve the isolation characteristic and transmission efficiency. Furthermore, to minimize the reflectivity of the port connected with the RF circuit, wave-absorbing material (WAM) is loaded in the resonator. Simulation results for the YTBW loaded with WAM predict an excellent performance with a 50.2% relative bandwidth for port reflectivity under −15 dB, transmission up to −1.5 dB, and meanwhile isolation under −20 dB. In addition, the coupler has a relatively compact configuration and the beam tunnel can be widened, which is beneficial for the propagation of the electrons. A Q-band YTBW loaded with two reflection resonators is fabricated and microwave tested. Vector network analyzer (VNA) measured results have an excellent agreement with our simulation, which verify our theoretical analysis and simulation calculation

  17. Design and microwave test of an ultrawideband input/output structure for sheet beam travelling wave tubes

    Energy Technology Data Exchange (ETDEWEB)

    Shu, Guoxiang; Wang, Jianxun; Liu, Guo; Yang, Liya; Luo, Yong [School of Physical Electronics, University of Electronic Science and Technology of China, Chengdu 610054 (China); Wang, Shafei [North Electronic Device Research Institution, P.O. Box 947, Beijing 100141 (China)

    2015-06-15

    Broadband operation is of great importance for the applications of travelling wave tubes such as high-data communication and wideband radar. An input/output (I/O) structure operating with broadband property plays a significant role to achieve these applications. In this paper, a Y-type branch waveguide (YTBW) coupler and its improvements are proposed and utilized to construct an extremely wideband I/O structure to ensure the broadband operation for sheet beam travelling wave tubes (SB-TWTs). Cascaded reflection resonators are utilized to improve the isolation characteristic and transmission efficiency. Furthermore, to minimize the reflectivity of the port connected with the RF circuit, wave-absorbing material (WAM) is loaded in the resonator. Simulation results for the YTBW loaded with WAM predict an excellent performance with a 50.2% relative bandwidth for port reflectivity under −15 dB, transmission up to −1.5 dB, and meanwhile isolation under −20 dB. In addition, the coupler has a relatively compact configuration and the beam tunnel can be widened, which is beneficial for the propagation of the electrons. A Q-band YTBW loaded with two reflection resonators is fabricated and microwave tested. Vector network analyzer (VNA) measured results have an excellent agreement with our simulation, which verify our theoretical analysis and simulation calculation.

  18. Design Evaluation of Thermal-hydraulic Test Facility for a Finned-tube Sodium-to-Air Heat Exchanger

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Hyungmo; Kim, Byeong-Yeon; Ko, Yung Joo; Cho, Youngil; Kim, Jong-Man; Son, Seok-Kwon; Jo, Youngchul; Kang, Byeong Su; Jung, Minhwan; Eoh, Jaehyuk; Lee, Hyeong-Yeon; Jeong, Ji-Young [KAERI, Daejeon (Korea, Republic of)

    2016-05-15

    This paper introduces the recent progress of overall design phase for the SELFA facility and deals with basic thermal-hydraulic design parameters and its design validation as well. For more reliable design of the safety-grade decay heat removal system (DHRS) in PGSFR (Prototype Gen-IV Sodium-cooled Fast Reactor), two kinds of sodium-to-air heat exchangers have been employed in the system as an ultimate heat sink. One is a natural draft sodium-to-air heat exchanger (AHX) with helically-coiled sodium tubes, and the other is a forced draft sodium-to-air heat exchanger (FHX) with finned tubes with a straight-type arranged. Since the FHX is normally operated in an active mode with a forced air draft conditions, its performance should be verified for any anticipated operating conditions. To validate the test section design, evaluations of both thermal-hydraulic and mechanical design have been carried out, and some new concepts or devices were newly employed to replicate the prototypic conditions as closely as possible.

  19. Lay perceptions of predictive testing for diabetes based on DNA test results versus family history assessment: a focus group study.

    Science.gov (United States)

    Wijdenes-Pijl, Miranda; Dondorp, Wybo J; Timmermans, Danielle Rm; Cornel, Martina C; Henneman, Lidewij

    2011-07-05

    This study assessed lay perceptions of issues related to predictive genetic testing for multifactorial diseases. These perceived issues may differ from the "classic" issues, e.g. autonomy, discrimination, and psychological harm that are considered important in predictive testing for monogenic disorders. In this study, type 2 diabetes was used as an example, and perceptions with regard to predictive testing based on DNA test results and family history assessment were compared. Eight focus group interviews were held with 45 individuals aged 35-70 years with (n = 3) and without (n = 1) a family history of diabetes, mixed groups of these two (n = 2), and diabetes patients (n = 2). All interviews were transcribed and analysed using Atlas-ti. Most participants believed in the ability of a predictive test to identify people at risk for diabetes and to motivate preventive behaviour. Different reasons underlying motivation were considered when comparing DNA test results and a family history risk assessment. A perceived drawback of DNA testing was that diabetes was considered not severe enough for this type of risk assessment. In addition, diabetes family history assessment was not considered useful by some participants, since there are also other risk factors involved, not everyone has a diabetes family history or knows their family history, and it might have a negative influence on family relations. Respect for autonomy of individuals was emphasized more with regard to DNA testing than family history assessment. Other issues such as psychological harm, discrimination, and privacy were only briefly mentioned for both tests. The results suggest that most participants believe a predictive genetic test could be used in the prevention of multifactorial disorders, such as diabetes, but indicate points to consider before both these tests are applied. These considerations differ with regard to the method of assessment (DNA test or obtaining family history) and also differ from

  20. Lay perceptions of predictive testing for diabetes based on DNA test results versus family history assessment: a focus group study

    Directory of Open Access Journals (Sweden)

    Cornel Martina C

    2011-07-01

    Full Text Available Abstract Background This study assessed lay perceptions of issues related to predictive genetic testing for multifactorial diseases. These perceived issues may differ from the "classic" issues, e.g. autonomy, discrimination, and psychological harm that are considered important in predictive testing for monogenic disorders. In this study, type 2 diabetes was used as an example, and perceptions with regard to predictive testing based on DNA test results and family history assessment were compared. Methods Eight focus group interviews were held with 45 individuals aged 35-70 years with (n = 3 and without (n = 1 a family history of diabetes, mixed groups of these two (n = 2, and diabetes patients (n = 2. All interviews were transcribed and analysed using Atlas-ti. Results Most participants believed in the ability of a predictive test to identify people at risk for diabetes and to motivate preventive behaviour. Different reasons underlying motivation were considered when comparing DNA test results and a family history risk assessment. A perceived drawback of DNA testing was that diabetes was considered not severe enough for this type of risk assessment. In addition, diabetes family history assessment was not considered useful by some participants, since there are also other risk factors involved, not everyone has a diabetes family history or knows their family history, and it might have a negative influence on family relations. Respect for autonomy of individuals was emphasized more with regard to DNA testing than family history assessment. Other issues such as psychological harm, discrimination, and privacy were only briefly mentioned for both tests. Conclusion The results suggest that most participants believe a predictive genetic test could be used in the prevention of multifactorial disorders, such as diabetes, but indicate points to consider before both these tests are applied. These considerations differ with regard to the method of assessment

  1. Economic Crisis and Marital Problems in Turkey: Testing the Family Stress Model

    Science.gov (United States)

    Aytac, Isik A.; Rankin, Bruce H.

    2009-01-01

    This paper applied the family stress model to the case of Turkey in the wake of the 2001 economic crisis. Using structural equation modeling and a nationally representative urban sample of 711 married women and 490 married men, we tested whether economic hardship and the associated family economic strain on families resulted in greater marital…

  2. Family Meal Frequency and Alcohol and Tobacco Use in Adolescence: Testing Reciprocal Effects

    Science.gov (United States)

    White, James; Halliwell, Emma

    2011-01-01

    This longitudinal study tested the direction of associations between family meals and alcohol and tobacco consumption during early adolescence. We examined family meal frequency, family connectedness, alcohol (binge drinking, drunkenness), and tobacco consumption (past year, daily frequency) in 671 adolescents (51% women; mean age, Wave 1 = 14.05…

  3. Development and Execution of a Large-scale DDT Tube Test for IHE Material Qualification

    Energy Technology Data Exchange (ETDEWEB)

    Parker, Gary Robert [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Broilo, Robert M. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Lopez-Pulliam, Ian Daniel [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Vaughan, Larry Dean [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-10-24

    Insensitive High Explosive (IHE) Materials are defined in Chapter IX of the DOE Explosive Safety Standard (DOE-STD-1212-2012) as being materials that are massdetonable explosives that are so insensitive that the probability of accidental initiation or transition from burning to detonation is negligible1. There are currently a number of tests included in the standard that are required to qualify a material as IHE, however, none of the tests directly evaluate for the transition from burning to detonation (aka deflagration-to-detonation transition, DDT). Currently, there is a DOE complex-wide effort to revisit the IHE definition in DOE-STD-1212-2012 and change the qualification requirements. The proposal lays out a new approach, requiring fewer, but more appropriate tests, for IHE Material qualification. One of these new tests is the Deflagration-to-Detonation Test. According to the redefinition proposal, the purpose of the new deflagration-todetonation test is “to demonstrate that an IHE material will not undergo deflagration-to-detonation under stockpile relevant conditions of scale, confinement, and material condition. Inherent in this test design is the assumption that ignition does occur, with onset of deflagration. The test design will incorporate large margins and replicates to account for the stochastic nature of DDT events.” In short, the philosophy behind this approach is that if a material fails to undergo DDT in a significant over-test, then it is extremely unlikely to do so in realistic conditions. This effort will be valuable for the B61 LEP to satisfy their need qualify the new production lots of PBX 9502. The work described in this report is intended as a preliminary investigation to support the proposed design of an overly conservative, easily fielded DDT test for updated IHE Material Qualification standard. Specifically, we evaluated the aspects of confinement, geometry, material morphology and temperature. We also developed and tested a

  4. 30 CFR 7.28 - Test for flame resistance of rigid ventilation tubing.

    Science.gov (United States)

    2010-07-01

    ... size. (2) For each test, suspend the sample in the center of the gallery by running a wire through the...) Record the propagation length and duration of burning for each of the 6 samples. The duration of burn is the total burning time of the specimen during the flame test. This includes the burning time of any...

  5. Thermal-hydraulic tests on net divertor targets using swirl tubes

    International Nuclear Information System (INIS)

    Schlosser, J.; Chappuis, P.; Deschamps, P.; Massmann, P.; Falter, H.D.; Deschamps, G.H.

    1991-01-01

    Thermal-hydraulic tests have been carried out in collaboration between NET, CEA Cadarache and JET in order to find a cooling method capable of removing the high heat fluxes expected for the NET/ITER divertor. The goal was to evaluate by experiments the critical heat flux (CHF) and heat transfer in the subcooled boiling regime using twisted tapes as turbulence promoters and testing them under relevant thermal-hydraulic conditions. The CEA 200 kW Electron Beam (EB) facility and the 10 MW JET Neutral Beam (NB) test bed have been used to heat up the NET relevant test sections (TS) consisting of rectangular copper elements with circular internal channels. The TS have been exposed to the electron or ion beams under normal incidence. This paper reports the results of the experiments and of thermal analyses performed in support of the tests. The experimental CHF values have been benchmarked with the Tong-75 correlation

  6. The Development of Expansion Plug Wedge Test for Clad Tubing Structure Mechanical Property Evaluation

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Jy-An John [ORNL; Jiang, Hao [ORNL

    2016-01-12

    To determine the tensile properties of irradiated fuel cladding in a hot cell, a simple test was developed at the Oak Ridge National Laboratory (ORNL) and is described fully in US Patent Application 20060070455, “Expanded plug method for developing circumferential mechanical properties of tubular materials.” This method is designed for testing fuel rod cladding ductility in a hot cell using an expandable plug to stretch a small ring of irradiated cladding material. The specimen strain is determined using the measured diametrical expansion of the ring. This method removes many complexities associated with specimen preparation and testing. The advantages are the simplicity of measuring the test component assembly in the hot cell and the direct measurement of the specimen’s strain. It was also found that cladding strength could be determined from the test results.

  7. Technology development on production of test specimens from irradiated capsule outer-tube and mechanical evaluation test of stainless steel with high dose carried out by the technology

    International Nuclear Information System (INIS)

    Hayashi, Koji; Shibata, Akira; Iwamatsu, Shigemi; Sozawa, Shizuo; Takada, Fumiki; Ohmi, Masao; Nakagawa, Tetsuya

    2008-03-01

    The irradiation capsule 74M-52J was irradiated during total 136 cycles at reactor core of JMTR and the maximum neutron dose reached on 3.9x10 26 n/m 2 at the capsule outer-tube made of a type 304 stainless steel. In order to produce mechanical test specimens from the outer-tube, a punching technique was developed as a simple remote-handling method in a hot-cell. From comparison between the punching and the mechanical cutting methods, it was clarified that the punching technique was applicable to practical use. Moreover, an evaluation test of mechanical properties using specimens sampled from the 74M-52 was performed with in-water high temperature condition, less than 288degC. The result shows that the residual elongation is 18% at 150degC and 13% at 288degC. It was confirmed that the type 304 stainless steel irradiated up to such high dose shows enough ductility. (author)

  8. {open_quotes}O{close_quotes} ring sealed process tube, Phase II, test project

    Energy Technology Data Exchange (ETDEWEB)

    Johnson, R.E.

    1951-04-09

    The {open_quotes}O{close_quotes} ring seal has been proposed to replace the van stone flange and the bellows thermal expansion assembly currently used on the existing Hanford piles to achieve water and gas seals, respectively. Possible advantages of the {open_quotes}O{close_quotes} ring seal are: (1) simplification of component parts and elimination of van stone corrosion; (2) simplification of maintenance; (3) lower costs of initial erection; (4) increased strength. This test supplements Test Project No. 27 (a preliminary thermal cycling test) in applying the {open_quotes}O{close_quotes} ring seal assembly to actual pile operating conditions.

  9. Tube plug

    International Nuclear Information System (INIS)

    Zafred, P. R.

    1985-01-01

    The tube plug comprises a one piece mechanical plug having one open end and one closed end which is capable of being inserted in a heat exchange tube and internally expanded into contact with the inside surface of the heat exchange tube for preventing flow of a coolant through the heat exchange tube. The tube plug also comprises a groove extending around the outside circumference thereof which has an elastomeric material disposed in the groove for enhancing the seal between the tube plug and the tube

  10. Coincident steam generator tube rupture and stuck-open safety relief valve carryover tests: MB-2 steam generator transient response test program

    International Nuclear Information System (INIS)

    Garbett, K.; Mendler, O.J.; Gardner, G.C.; Garnsey, R.; Young, M.Y.

    1987-03-01

    In PWR steam generator tube rupture (SGTR) faults, a direct pathway for the release of radioactive fission products can exist if there is a coincident stuck-open safety relief valve (SORV) or if the safety relief valve is cycled. In addition to the release of fission products from the bulk steam generator water by moisture carryover, there exists the possibility that some primary coolant may be released without having first mixed with the bulk water - a process called primary coolant bypassing. The MB-2 Phase II test program was designed specifically to identify the processes for droplet carryover during SGTR faults and to provide data of sufficient accuracy for use in developing physical models and computer codes to describe activity release. The test program consisted of sixteen separate tests designed to cover a range of steady-state and transient fault conditions. These included a full SGTR/SORV transient simulation, two SGTR overfill tests, ten steady-state SGTR tests at water levels ranging from very low levels in the bundle up to those when the dryer was flooded, and three moisture carryover tests without SGTR. In these tests the influence of break location and the effect of bypassing the dryer were also studied. In a final test the behavior with respect to aerosol particles in a dry steam generator, appropriate to a severe accident fault, was investigated

  11. Alterations in rotation thromboelastometry (ROTEM®) parameters: point-of-care testing vs analysis after pneumatic tube system transport.

    Science.gov (United States)

    Martin, J; Schuster, T; Moessmer, G; Kochs, E F; Wagner, K J

    2012-10-01

    Thromboelastometry as point-of-care (POC) testing enables the analysis of the clotting process at the bedside, providing rapid results to guide haemostatic therapy. However, POC testing utilizes medical staff who are managing critically ill patients, as non-laboratory personnel may not be sufficiently trained to run the devices. To resolve these problems, thromboelastometry can be performed in the central laboratory and rapid transport of samples can be accomplished via a pneumatic tube system (PTS). This study compares thromboelastometry parameters of blood samples analysed immediately with those analysed after PTS transport. In patients with normal haemostasis, two arterial blood samples were collected from each patient (n=92) in citrated plastic tubes to investigate the assays INTEM (n=35), EXTEM (n=27), and FIBTEM (n=30). One blood sample was analysed immediately, the other sample after PTS transport. Thromboelastometry was performed using a single ROTEM(®) device. The mean clot firmness values were significantly lower for PTS samples in both the INTEM (-0.7 mm cf. -1.1 mm) and EXTEM (-1.4 cf. -1.7 mm) assays. INTEM coagulation time (CT) was significantly lower in PTS samples with a mean difference of -13 s. EXTEM CT was significantly higher in PTS samples with a mean difference of +3.9 s. Thromboelastometry parameters of blood samples analysed after PTS transport are significantly altered compared with those analysed immediately. However, in patients with normal haemostasis, the alterations were small and without clinical consequence, implying that analysis after PTS transport is an acceptable alternative to prompt analysis at the bedside. Further studies should focus on patients with impaired haemostasis.

  12. Comparison of characteristics parameters in the evaluation of wall thickness diminishing in admiralty brass tubes of the steam condenser, tested by eddy currents

    International Nuclear Information System (INIS)

    Obrutsky, Alba E.; Mendez, Jorge A.; Acosta, Cesar D.; Scopelliti, Jose D.

    1999-01-01

    This work is aimed to appraise the measure of the wall thickness diminishing in the signals evaluation obtained in the inspection of steam condenser by eddy currents. In the analysis of the obtained signals were observed in the brass tubes a great quantity of internal defects whose signal indicates that there were diminishing of the wall thickness between 80% and 100%. With all this information and analyzing the data acquired, the tubes with more important indications were selected to make a more exhaustive study of the found defectology. As first test, it was measured the thickness of the worn tubes, comparing them with the original ones that are in stock. It was verified that the tubes separated for this study presented a 30% less thickness in comparison with the new tubes. A semiquantitative chemical test (EDAX) was made to verify if it was the same material. One of the extracted tubes (066 Y1) was reinspected in order to isolate the area with indications. Once this was performed, it was decided to cut the tube to make a visual inspection and to evaluate to what type of defect corresponds to the signals obtained. In the metallography it was confirm that it was a horseshoe type defect. When performing a dimensional control test of the found real defect, it was checked that the information obtained by eddy currents regarding the diminishing of the wall thickness diminishing was valid. At a last stage of the test, it was proceed to make an study and verification of the used parameters, probes, standards and finally determine which shall be the convenient modifications to minimize errors. (author)

  13. Vibration instrumentation of the tubes of the Paluel 1 steam generator no.4. Results of tests

    International Nuclear Information System (INIS)

    Gay, N.; Campistron, R.; Launay, J.

    1985-06-01

    This report gives an overview of the instrumentation and of the measuring unit. Then the different tests carried out as also their exploitation are presented. The results are presented in the lasp part [fr

  14. Hydraulic Testing of Polymer Matrix Composite 102mm Tube Section Technical Report

    Science.gov (United States)

    2018-04-01

    official Department of the Army position, policy, or decision, unless so designated by other documentation. The citation in this report of the names...the test specimen bore to measure strain in the hoop direction. Axial location of the interior strain gages was in the center of the test specimen...material. Each interior hoop direction strain gage contained a three-wire set-up for ease of balancing the bridge. Each internal strain gage wiring

  15. Reliable experimental setup to test the pressure modulation of Baerveldt Implant tubes for reducing post-operative hypotony

    Science.gov (United States)

    Ramani, Ajay

    Glaucoma encompasses a group of conditions that result in damage to the optic nerve and can cause loss of vision and blindness. The nerve is damaged due to an increase in the eye's internal (intraocular) pressure (IOP) above the nominal range of 15 -- 20 mm Hg. There are many treatments available for this group of diseases depending on the complexity and stage of nerve degradation. In extreme cases where drugs or laser surgery do not create better conditions for the patient, ophthalmologists use glaucoma drainage devices to help alleviate the IOP. Many drainage implants have been developed over the years and are in use; but two popular implants are the Baerveldt Glaucoma Implant and the Ahmed Glaucoma Valve Implant. Baerveldt Implants are non-valved and provide low initial resistance to outflow of fluid, resulting in post-operative complications such as hypotony, where the IOP drops below 5 mm of Hg. Ahmed Glaucoma Valve Implants are valved implants which initially restrict the amount of fluid flowing out of the eye. The long term success rates of Baerveldt Implants surpass those of Ahmed Valve Implants because of post-surgical issues; but Baerveldt Implants' initial effectiveness is poor without proper flow restriction. This drives the need to develop new ways to improve the initial effectiveness of Baerveldt Implants. A possible solution proposed by our research team is to place an insert in the Baerveldt Implant tube of inner diameter 305 microns. The insert must be designed to provide flow resistance for the early time frame [e.g., first 30 -- 60 post-operative days] until sufficient scar tissue has formed on the implant. After that initial stage with the insert, the scar tissue will provide the necessary flow resistance to maintain the IOP above 5 mm Hg. The main objective of this project was to develop and validate an experimental apparatus to measure pressure drop across a Baerveldt Implant tube, with and without inserts. This setup will be used in the

  16. Development of Cone Wedge Ring Expansion Test to Evaluate Mechanical Properties of Clad Tubing Structure

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Jy-An John [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2016-10-01

    To determine the hoop tensile properties of irradiated fuel cladding in a hot cell, a cone wedge ring expansion test method was developed. A four-piece wedge insert was designed with tapered angles matched to the cone shape of a loading piston. The ring specimen was expanded in the radial direction by the lateral expansion of the wedges under the downward movement of the piston. The advantages of the proposed method are that implementation of the test setup in a hot cell is simple and easy, and that it enables a direct strain measurement of the test specimen from the piston’s vertical displacement soon after the wedge-clad contact resistance is initiated.

  17. Gastrostomy Tube (G-Tube)

    Science.gov (United States)

    ... any of these problems: a dislodged tube a blocked or clogged tube any signs of infection (including redness, swelling, or warmth at the tube site; discharge that's yellow, green, or foul-smelling; fever) excessive bleeding or drainage from the tube site severe abdominal pain lasting ...

  18. Exploring experience of family relations by patients with anorexia nervosa and bulimia nervosa using a projective family test.

    Science.gov (United States)

    Fäldt Ciccolo, Erica B

    2008-08-01

    Elements of family dynamics have been shown to be related to onset, course, as well as prognosis of anorexia nervosa and bulimia nervosa. The goal was to explore the experience of family relations in a group of patients with eating disorders using a projective family test. The Patient group (anorexia=21, bulimia=16), as well as a healthy Control group, were given a projective family test, the Eating Disorder Inventory-2, as well as Karolinska Scales of Personality. The Patient group expressed more discord within the family picture than the Control group, such as cold and loveless relationships and not feeling validated. The group of patients reporting the most family discord did not show more eating disorder pathology or general psychopathology. They did, however, have higher scores on the Eating Disorder Inventory-2 subscale Maturity Fears, as well as higher values on the Karolinska Scales of Personality subscale Socialization. These results are interpreted within the background of methodological challenges in this area of research.

  19. Influence of Test Section Geometry on the Blast Environment in an Explosively Driven Conical Shock Tube

    Science.gov (United States)

    2018-03-30

    ARL-TR-8335•MAR 2018 US Army Research Laboratory Influence of Test Section Geometry on theBlast Environment in an Explosively DrivenConical Shock...ARL-TR-8335•MAR 2018 US Army Research Laboratory Influence of Test Section Geometry on theBlast Environment in an Explosively DrivenConical Shock...TITLE AND SUBTITLE    5a. CONTRACT NUMBER  5b. GRANT NUMBER  5c. PROGRAM ELEMENT NUMBER 6. AUTHOR(S)    5d.  PROJECT  NUMBER  5e. TASK NUMBER  5f

  20. The Implications of Family Size and Birth Order for Test Scores and Behavioral Development

    Science.gov (United States)

    Silles, Mary A.

    2010-01-01

    This article, using longitudinal data from the National Child Development Study, presents new evidence on the effects of family size and birth order on test scores and behavioral development at age 7, 11 and 16. Sibling size is shown to have an adverse causal effect on test scores and behavioral development. For any given family size, first-borns…

  1. Construction and test of the final CMS Barrel Drift Tube Muon Chamber prototype

    Energy Technology Data Exchange (ETDEWEB)

    Aguilar-Benitez, M.; Alberdi, J.; Arneodo, M.; Banicz, K.; Benettoni, M.; Benvenuti, A.; Bethke, S.; Cerrada, M. E-mail: cerrada@ciemat.es; Cirio, R.; Colino, N.; Conti, E.; Dallavalle, M.; Daniel, M.; Dattola, D.; Daudo, F.; De Giorgi, M.; Dosselli, U.; Fanfani, A.; Fanin, C.; Fouz, M.C.; Gasparini, F.; Gasparini, U.; Giacomelli, P.; Giordano, V.; Gonella, F.; Grandi, C.; Guaita, P.; Guerzoni, M.; Lacaprara, S.; Lippi, I.; Marcellini, S.; Marin, J.; Martinelli, R.; Maselli, S.; Meneguzzo, A.; Migliore, E.; Mocholi, J.; Monaco, V.; Montanari, A.; Montanari, C.; Odorici, F.; Oller, J.C.; Paoletti, S.; Passaseo, M.; Pegoraro, M.; Peroni, C.; Puerta, J.; Reithler, H.; Romero, A.; Romero, L.; Ronchese, P.; Rossi, A.M.; Rovelli, T.; Sacchi, R.; Salicio, J.M.; Staiano, A.; Steinbeck, T.; Torassa, E.; Travaglini, R.; Ventura, L.; Ventura, S.; Vitelli, A.; Voetee, F.; Wegner, M.; Willmott, C.; Zotto, P.; Zumerle, G

    2002-03-21

    A prototype of the CMS Barrel Muon Detector incorporating all the features of the final chambers was built using the mass production assembly procedures and tools. The performance of this prototype was studied in a muon test beam at CERN and the results obtained are presented in this paper.

  2. Study of methods for testing the tubes of steam generators by means of Eddy Current

    International Nuclear Information System (INIS)

    Oehnfeldt, C.-G.

    1982-01-01

    Comparative studies of equipment have been performed at Ringhals. Automatic testing systems, type Vincotte have been found to be flexible. Multi-frequency systems are to be preferred. The limits of detection of defects can be estimated in three classes including defects which are impossible to detect. Real defects in Ringhals-2 and Ringhals-3 were used as reference. (G.B.)

  3. Some questions of the technique of high-voltage testing of accele-- rating tube space in electrostatic accelerators

    International Nuclear Information System (INIS)

    Romanov, V.A.; Ivanov, V.V.; Mukhametshin, V.I.; Dmitriev, E.P.; Kidalov, A.I.

    1983-01-01

    In the course of high-voltage testing of accelerating spaces a wide spread of experimental values of electric strength is observed. This circumstance is determined by a number of factors one of which is the technique used for high-voltage testing. For the purpose of obtaining more reliable experimental data on electric strength of accelerating spaces it is suggested to take for a criterion of electric strength of an accelerating space in long accelerating tubes a long-time withstood voltage which is equal approximately to a doubled working space voltage obtained as a result of a smooth voltage rise at dark current density not exceeding (1...5)x10 -2 A/cm 2 . In the course of testing of accelerating spaces of 25 mm height with total working area of electrodes approximately 360 cm 2 and insulator area onto vacuum approximately 150 cm 2 a long-time 70 kV voltage with dark current less than 1.10 -8 A is obtained

  4. Lifetime prediction and reliability estimation methodology for Stirling-type pulse tube refrigerators by gaseous contamination accelerated degradation testing

    Science.gov (United States)

    Wan, Fubin; Tan, Yuanyuan; Jiang, Zhenhua; Chen, Xun; Wu, Yinong; Zhao, Peng

    2017-12-01

    Lifetime and reliability are the two performance parameters of premium importance for modern space Stirling-type pulse tube refrigerators (SPTRs), which are required to operate in excess of 10 years. Demonstration of these parameters provides a significant challenge. This paper proposes a lifetime prediction and reliability estimation method that utilizes accelerated degradation testing (ADT) for SPTRs related to gaseous contamination failure. The method was experimentally validated via three groups of gaseous contamination ADT. First, the performance degradation model based on mechanism of contamination failure and material outgassing characteristics of SPTRs was established. Next, a preliminary test was performed to determine whether the mechanism of contamination failure of the SPTRs during ADT is consistent with normal life testing. Subsequently, the experimental program of ADT was designed for SPTRs. Then, three groups of gaseous contamination ADT were performed at elevated ambient temperatures of 40 °C, 50 °C, and 60 °C, respectively and the estimated lifetimes of the SPTRs under normal condition were obtained through acceleration model (Arrhenius model). The results show good fitting of the degradation model with the experimental data. Finally, we obtained the reliability estimation of SPTRs through using the Weibull distribution. The proposed novel methodology enables us to take less than one year time to estimate the reliability of the SPTRs designed for more than 10 years.

  5. Assaying embryotoxicity in the test tube: current limitations of the embryonic stem cell test (EST) challenging its applicability domain.

    Science.gov (United States)

    Riebeling, Christian; Hayess, Katrin; Peters, Annelieke K; Steemans, Margino; Spielmann, Horst; Luch, Andreas; Seiler, Andrea E M

    2012-05-01

    Testing for embryotoxicity in vitro is an attractive alternative to animal experimentation. The embryonic stem cell test (EST) is such a method, and it has been formally validated by the European Centre for the Validation of Alternative Methods. A number of recent studies have underscored the potential of this method. However, the EST performed well below the 78% accuracy expected from the validation study using a new set of chemicals and pharmaceutical compounds, and also of toxicity criteria, tested to enlarge the database of the validated EST as part of the Work Package III of the ReProTect Project funded within the 6th Framework Programme of the European Union. To assess the performance and applicability domain of the EST we present a detailed review of the substances and their effects in the EST being nitrofen, ochratoxin A, D-penicillamine, methylazoxymethanol, lovastatin, papaverine, warfarin, β-aminopropionitrile, dinoseb, furosemide, doxylamine, pravastatin, and metoclopramide. By delineation of the molecular mechanisms of the substances we identify six categories of reasons for misclassifications. Some of these limitations might also affect other in vitro methods assessing embryotoxicity. Substances that fall into these categories need to be included in future validation sets and in validation guidelines for embryotoxicity testing. Most importantly, we suggest conceivable improvements and additions to the EST which will resolve most of the limitations.

  6. An immunologic model for rapid vaccine assessment -- a clinical trial in a test tube.

    Science.gov (United States)

    Higbee, Russell G; Byers, Anthony M; Dhir, Vipra; Drake, Donald; Fahlenkamp, Heather G; Gangur, Jyoti; Kachurin, Anatoly; Kachurina, Olga; Leistritz, Del; Ma, Yifan; Mehta, Riyaz; Mishkin, Eric; Moser, Janice; Mosquera, Luis; Nguyen, Mike; Parkhill, Robert; Pawar, Santosh; Poisson, Louis; Sanchez-Schmitz, Guzman; Schanen, Brian; Singh, Inderpal; Song, Haifeng; Tapia, Tenekua; Warren, William; Wittman, Vaughan

    2009-09-01

    While the duration and size of human clinical trials may be difficult to reduce, there are several parameters in pre-clinical vaccine development that may be possible to further optimise. By increasing the accuracy of the models used for pre-clinical vaccine testing, it should be possible to increase the probability that any particular vaccine candidate will be successful in human trials. In addition, an improved model will allow the collection of increasingly more-informative data in pre-clinical tests, thus aiding the rational design and formulation of candidates entered into clinical evaluation. An acceleration and increase in sophistication of pre-clinical vaccine development will thus require the advent of more physiologically-accurate models of the human immune system, coupled with substantial advances in the mechanistic understanding of vaccine efficacy, achieved by using this model. We believe the best viable option available is to use human cells and/or tissues in a functional in vitro model of human physiology. Not only will this more accurately model human diseases, it will also eliminate any ethical, moral and scientific issues involved with use of live humans and animals. An in vitro model, termed "MIMIC" (Modular IMmune In vitro Construct), was designed and developed to reflect the human immune system in a well-based format. The MIMIC System is a laboratory-based methodology that replicates the human immune system response. It is highly automated, and can be used to simulate a clinical trial for a diverse population, without putting human subjects at risk. The MIMIC System uses the circulating immune cells of individual donors to recapitulate each individual human immune response by maintaining the autonomy of the donor. Thus, an in vitro test system has been created that is functionally equivalent to the donor's own immune system and is designed to respond in a similar manner to the in vivo response. 2009 FRAME.

  7. Is Self-Regulation "All in the Family"? Testing Environmental Effects Using Within-Family Quasi-Experiments

    Science.gov (United States)

    Deater-Deckard, Kirby

    2016-01-01

    Most of the individual difference variance in the population is found "within" families, yet studying the processes causing this variation is difficult due to confounds between genetic and nongenetic influences. Quasi-experiments can be used to test hypotheses regarding environment exposure (e.g., timing, duration) while controlling for…

  8. Tumor Suppressor Gene-Based Nanotherapy: From Test Tube to the Clinic

    Directory of Open Access Journals (Sweden)

    Manish Shanker

    2011-01-01

    Full Text Available Cancer is a major health problem in the world. Advances made in cancer therapy have improved the survival of patients in certain types of cancer. However, the overall five-year survival has not significantly improved in the majority of cancer types. Major challenges encountered in having effective cancer therapy are development of drug resistance by the tumor cells, nonspecific cytotoxicity, and inability to affect metastatic tumors by the chemodrugs. Overcoming these challenges requires development and testing of novel therapies. One attractive cancer therapeutic approach is cancer gene therapy. Several laboratories including the authors' laboratory have been investigating nonviral formulations for delivering therapeutic genes as a mode for effective cancer therapy. In this paper the authors will summarize their experience in the development and testing of a cationic lipid-based nanocarrier formulation and the results from their preclinical studies leading to a Phase I clinical trial for nonsmall cell lung cancer. Their nanocarrier formulation containing therapeutic genes such as tumor suppressor genes when administered intravenously effectively controls metastatic tumor growth. Additional Phase I clinical trials based on the results of their nanocarrier formulation have been initiated or proposed for treatment of cancer of the breast, ovary, pancreas, and metastatic melanoma, and will be discussed.

  9. Tumor suppressor gene-based nanotherapy: from test tube to the clinic.

    Science.gov (United States)

    Shanker, Manish; Jin, Jiankang; Branch, Cynthia D; Miyamoto, Shinya; Grimm, Elizabeth A; Roth, Jack A; Ramesh, Rajagopal

    2011-01-01

    Cancer is a major health problem in the world. Advances made in cancer therapy have improved the survival of patients in certain types of cancer. However, the overall five-year survival has not significantly improved in the majority of cancer types. Major challenges encountered in having effective cancer therapy are development of drug resistance by the tumor cells, nonspecific cytotoxicity, and inability to affect metastatic tumors by the chemodrugs. Overcoming these challenges requires development and testing of novel therapies. One attractive cancer therapeutic approach is cancer gene therapy. Several laboratories including the authors' laboratory have been investigating nonviral formulations for delivering therapeutic genes as a mode for effective cancer therapy. In this paper the authors will summarize their experience in the development and testing of a cationic lipid-based nanocarrier formulation and the results from their preclinical studies leading to a Phase I clinical trial for nonsmall cell lung cancer. Their nanocarrier formulation containing therapeutic genes such as tumor suppressor genes when administered intravenously effectively controls metastatic tumor growth. Additional Phase I clinical trials based on the results of their nanocarrier formulation have been initiated or proposed for treatment of cancer of the breast, ovary, pancreas, and metastatic melanoma, and will be discussed.

  10. Drug-mediated toxicity: illuminating the 'bad' in the test tube by means of cellular assays?

    Science.gov (United States)

    Tralau, Tewes; Luch, Andreas

    2012-07-01

    Health problems are rising worldwide, be it as a consequence of lifestyle and longevity in increasingly affluent societies or due to a sharp rise in bacterial antibiotic resistance. The pharmaceutical industry is caught between high rates of attrition and the rather slow pace of a historically large regulatory system for pharmacological safety. Meanwhile, the past decade has seen a tremendous evolution of the biological toolbox, most notably of cellular assays, stem-cell differentiation and organ-mimicking systems. These systems were readily adapted for lead-compound identification. However, their use as toxicological test systems is lagging behind, not least because of a lack of regulatory acceptance. This review tries to elucidate the scale of the problem and discusses the applicability of the assays currently available, with particular regard to the use of stem cells. Copyright © 2012 Elsevier Ltd. All rights reserved.

  11. [Tuberculosis screening program for undocumented immigrant teenagers using the QuantiFERON(®)-TB Gold In-Tube test].

    Science.gov (United States)

    Salinas, Carlos; Ballaz, Aitor; Díez, Rosa; Aguirre, Urko; Antón, Ane; Altube, Lander

    2015-07-06

    The aim of this study was to determine the prevalence of tuberculosis infection in undocumented immigrant teenagers using a tuberculin skin test (TST) for initial screening and QuantiFERON(®)-TB Gold In-Tube (QFT-GIT) as a confirmatory test. From 2007 to 2012, under 19 year-old immigrant teenagers from 2 accommodation centers of the Basque Country (Spain) were included in the study. The TST was done in all of them and the QFT-GIT was done in selected patients with a TST≥5mm. Eight hundred and forty-five immigrants were included, most of them from Africa (99.5%). Fifty-one percent of immigrants with TST ≥ 5 mm has a positive QFT-GIT. We found 2 cases of active tuberculosis (2/845: 0.24%). The concordance between TST (≥ 10 mm) and QFT-GIT was 63%, with 57% of positive concordance cases and 96% of negative concordances. There were 246 cases with TST ≥ 10 mm (29%), with significant differences between Magrebis (21.5%) and Subsaharians (67%) (Ptuberculosis infection in Subsaharian immigrants, we recommend implementing screening programs in this population. Using QFT-GIT, the number of candidates for chemoprophylaxis was reduced to 43% compared with TST alone (≥ 10 mm). Copyright © 2013 Elsevier España, S.L.U. All rights reserved.

  12. Water-storage-tube systems. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Hemker, P.

    1981-12-24

    Passive solar collection/storage/distribution systems were surveyed, designed, fabricated, and mechanically and thermally tested. The types studied were clear and opaque fiberglass tubes, metal tubes with plastic liners, and thermosyphoning tubes. (MHR)

  13. Silencing of the pollen-specific gene NTP303 and its family members in tobacco affects in vivo pollen tube growth and results in male sterile plants

    NARCIS (Netherlands)

    Groot, de P.; Weterings, K.; Been, de M.; Wittink, F.; Hulzink, R.; Custers, J.B.M.; Herpen, van T.W.J.M.; Wullems, G.

    2004-01-01

    In seed plants, successful fertilization requires correct regulation of pollen tube growth. At germination and during growth, the pollen tube interacts with tissues from the pistil while the pollen tube extends via tip growth. Despite the fact that much research has been devoted to the mechanisms

  14. Mock-up tests on the combustion of hydrogen-air mixture in the vertical tube simulating the CNS channel of the CARR

    International Nuclear Information System (INIS)

    Yu Qingfeng; Feng Quanke; Kawai, Takeshi; Xu Jian

    2007-01-01

    A two-phase thermo-siphon loop for removing nuclear heating and maintaining the stable liquid level in the moderator cell was adopted for the cold neutron source (CNS) of the China advanced research reactor (CARR). The moderator is liquid hydrogen. The two-phase thermo-siphon loop consists of the crescent-shape moderator cell, the moderator transfer tube, and the condenser. The hydrogen is supplied from the buffer tank to the condenser. The main feature of the loop is that the moderator cell is covered by the helium sub-cooling system. The cold helium gas from the helium refrigerator is firstly introduced into the helium sub-cooling system and then flows up through the tube covering the moderator transfer tube into the condenser. The main part of this system is installed in the CNS vertical channel made of aluminum alloy 6061 T6 (Al-6061-T6) of 6 mm in thickness, 270 mm in outer diameter and about 6 m in height. For confirming the safety of the CNS channel, the combustion tests using a tube compatible with the CNS channel were carried out using the hydrogen-air mixture under which air is introduced into the tube at 1 atmosphere, and then hydrogen gas is supplied from the gas cylinder up to the test pressures. And maximum test pressure is 0.14 MPa G. This condition is involved with the maximum design basis accident of the CARR-CNS. The peak pressure due to combustion was 1.09 MPa, and the design pressure of the CNS channel is 3 MPa. The safety of the CNS was thus verified even if the maximum design basis accident occurs. The pressure and stress distributions along the axial direction and the displacement of the tube were also measured

  15. Effect of Resistance Tube Exercises on Kicking Accuracy, Vertical Jump and 40-Yard Technical Test in Competitive Football Players – An Experimental Study

    Directory of Open Access Journals (Sweden)

    Tirumala Alekhya

    2014-09-01

    Full Text Available Purpose. Kicking, jumping and agility are important skills in football. These activities require adequate lower limb strength, which can be enhanced with resistance training. The objective of the study was to evaluate the effect of resistance tube exercises on kicking accuracy, vertical jump performance and 40-yard technical test results in competitive football players. Methods. The study involved 23 competitive football players (11 males, 12 females aged from 18-20 years recruited from three different universities in Belgaum, Karnataka, India. Back heel kick accuracy, vertical jump height and 40-yard technical test time were evaluated before and after a 2-week resistance tube exercise program. Results. Significant improvements in post-intervention kicking accuracy were found when males and females were treated as a single group (p = 0.01. Vertical jump height also showed a highly significant post-intervention improvement in the males and for the combined group of males and females (p = 0.001. The 40-yard technical test values significantly improved in the females and in the combined results for males and females (p = 0.001. Conclusions. The two-week resistance tube exercise program was found to have an effect on kicking accuracy, vertical jump height and 40-yard technical test performance in competitive football players. Resistance tube exercises can thus be included as a component of a regular strength training program for such athletes.

  16. A UVC Device for Intra-luminal Disinfection of Catheters: In Vitro Tests on Soft Polymer Tubes Contaminated with Pseudomonas aeruginosa, Staphylococcus aureus, Escherichia coli and Candida albicans

    DEFF Research Database (Denmark)

    Bak, Jimmy; Begovic, Tanja; Bjarnsholt, Thomas

    2011-01-01

    light is possible. In this paper we present dose-response results using a newly developed UVC disinfection device, which can be connected to a Luer catheter hub. The device was tested on soft polymer tubes contaminated with a pallet of microorganisms, including Candida albicans, Staphylococcus aureus...

  17. 49 CFR 40.245 - What is the procedure for an alcohol screening test using a saliva ASD or a breath tube ASD?

    Science.gov (United States)

    2010-10-01

    ... process, take the device from the employee (or if you were holding it, remove it from the employee's mouth... direct the employee to take a new test immediately, using another type of ASD (e.g., saliva device) or an... a breath tube ASD? (a) As the STT or BAT, you must take the following steps when using the saliva...

  18. Superparamagnetic iron oxide nanoparticle attachment on array of micro test tubes and microbeakers formed on p-type silicon substrate for biosensor applications

    Directory of Open Access Journals (Sweden)

    Raja Sufi

    2011-01-01

    Full Text Available Abstract A uniformly distributed array of micro test tubes and microbeakers is formed on a p-type silicon substrate with tunable cross-section and distance of separation by anodic etching of the silicon wafer in N, N-dimethylformamide and hydrofluoric acid, which essentially leads to the formation of macroporous silicon templates. A reasonable control over the dimensions of the structures could be achieved by tailoring the formation parameters, primarily the wafer resistivity. For a micro test tube, the cross-section (i.e., the pore size as well as the distance of separation between two adjacent test tubes (i.e., inter-pore distance is typically approximately 1 μm, whereas, for a microbeaker the pore size exceeds 1.5 μm and the inter-pore distance could be less than 100 nm. We successfully synthesized superparamagnetic iron oxide nanoparticles (SPIONs, with average particle size approximately 20 nm and attached them on the porous silicon chip surface as well as on the pore walls. Such SPION-coated arrays of micro test tubes and microbeakers are potential candidates for biosensors because of the biocompatibility of both silicon and SPIONs. As acquisition of data via microarray is an essential attribute of high throughput bio-sensing, the proposed nanostructured array may be a promising step in this direction.

  19. Simulation of TunneLadder traveling-wave tube cold-test characteristics: Implementation of the three-dimensional, electromagnetic circuit analysis code micro-SOS

    Science.gov (United States)

    Kory, Carol L.; Wilson, Jeffrey D.

    1993-01-01

    The three-dimensional, electromagnetic circuit analysis code, Micro-SOS, can be used to reduce expensive time-consuming experimental 'cold-testing' of traveling-wave tube (TWT) circuits. The frequency-phase dispersion characteristics and beam interaction impedance of a TunneLadder traveling-wave tube slow-wave structure were simulated using the code. When reasonable dimensional adjustments are made, computer results agree closely with experimental data. Modifications to the circuit geometry that would make the TunneLadder TWT easier to fabricate for higher frequency operation are explored.

  20. The Sun-Duffey mass effluents calculation model applied to bottom reflooding tests of a single tube performed at the CDTN

    International Nuclear Information System (INIS)

    Ladeira, L.C.D.; Rezende, H.C.

    1993-01-01

    A simple generalized model, developed by K.H. Sun and R.B. Duffey, is applied in this work to calculate the ratio of mass effluents during bottom reflooding of a single tube carried out at the CDTN/CNEN. The results of the benchmark experiments indicate that the accuracy on mass effluence ratio prediction can be within 15% by using the Sun-Duffey model. The reasonable agreement obtained between experimental data and model predictions suggest that it could be used for analysis of single tube reflood tests, in similar conditions. (author)

  1. Use of thyroid-stimulating hormone tests for identifying primary hypothyroidism in family medicine patients.

    Science.gov (United States)

    Birk-Urovitz, Elizabeth; Elisabeth Del Giudice, M; Meaney, Christopher; Grewal, Karan

    2017-09-01

    To assess the use of thyroid-stimulating hormone (TSH) tests for identifying primary hypothyroidism in 2 academic family medicine settings. Descriptive study involving a retrospective electronic chart review of family medicine patients who underwent TSH testing. Two academic family practice sites: one site is within a tertiary hospital in Toronto, Ont, and the other is within a community hospital in Newmarket, Ont. A random sample of 205 adult family medicine patients who had 1 or more TSH tests for identifying potential primary hypothyroidism between July 1, 2009, and September 15, 2013. Exclusion criteria included a previous diagnosis of any thyroid condition or abnormality, as well as pregnancy or recent pregnancy within the year preceding the study period. The proportion of normal TSH test results and the proportion of TSH tests that did not conform to test-ordering guidelines. Of the 205 TSH test results, 200 (97.6%, 95% CI 94.4% to 99.2%) showed TSH levels within the normal range. All 5 patients with abnormal TSH test results had TSH levels above the upper reference limits. Nearly one-quarter (22.4%, 95% CI 16.9% to 28.8%) of tests did not conform to test-ordering guidelines. All TSH tests classified as not conforming to test-ordering guidelines showed TSH levels within normal limits. There was a significant difference ( P hypothyroidism case finding and screening was high, and the overall proportion of TSH tests that did not conform to test-ordering guidelines was relatively high as well. These results highlight a need for more consistent TSH test-ordering guidelines for primary hypothyroidism and perhaps some educational interventions to help curtail the overuse of TSH tests in the family medicine setting. Copyright© the College of Family Physicians of Canada.

  2. [Prenatal genetic counseling and instruction for deaf families by genetic test].

    Science.gov (United States)

    Han, Ming-yu; Huang, Sha-sha; Wang, Guo-jian; Yuan, Yong-yi; Kang, Dong-yang; Zhang, Xin; Dai, Pu

    2011-11-01

    Analyzed the molecular pathogenesis of probands by means of genetic test and assisted the local Family Planning Institute by providing prenatal genetic counseling and instruction for deaf families who eager to have more baby. Total of forty-three deaf families were recruited by two institutes for family planning from Guangzhou and Weifang. Forty-two families had one deaf child with normal hearing parents. One family was that parents and their child were all deaf. Genetic testing of GJB2, SLC26A4 and mitochondrial DNA (mtDNA) 12SrRNA were firstly performed in probands and their parents, following medical history, physical examination, auditory test and CT scan of temporal bone were completed. And then the genetic information and instruction were provided to each deaf family. Fifteen of these 43 families had positive results of genetic test. In fifteen families, one family was confirmed that the parents and their child all carried homozygous GJB2 mutations and the recurrence risk was 100%. Twelve families were confirmed that the probands carried homozygous/compound GJB2 or SLC26A4 mutations while their parents were GJB2 or SLC26A4 carriers, and the recurrence risk was 25%. One family was confirmed that the proband, diagnosed with enlarged vestibular aqueduct syndrome (EVAS) by CT scan, carried heterozygous SLC26A4 mutation from the mother, and the recurrence risk was still 25% based on the hereditary pattern of EVAS although another SLC26A4 mutation from the father was not found. One family was confirmed that the proband carried a heterozygous GJB2 mutation from the mother and the possibility to be GJB2 carrier for offsprings was 50%. The rest 28 families were that all probands and their parents did not carry GJB2, SLC26A4 and mtDNA 12SrRNA pathological mutation. Genetic testing can provide more accurate and useful prenatal genetic counseling and instruction to deaf families. Meanwhile, it is an ideal way to develop a cooperative relationship with the institute for

  3. [Delayed testing for the diagnosis of fungi in the urines. Evaluation of the BD Vacutainer C&S tubes for the storage of urine samples at room temperature].

    Science.gov (United States)

    Baixench, M T; Al-Sheikh, M; Paugam, A

    2005-01-01

    The study included 37 urine samples which have been artificially infected with low levels (10(3) CFU/mL) of various fungi strains. We compared the effects of sample storage, up to 48 hours, at room temperature, in a urine evacuated tube containing specific additives with storage at + 4 degrees C, for the same length of time, in a urine evacuated tube without any additives. There have been no differences of results (speed of growth and colony size) between the 2 modes of storage. However, the experience has shown that samples needed a careful mixing before seeding to avoid underdetection of the strains. Based on the study results, the BD Vacutainer C&S tubes are suitable for delayed testing for the diagnosis of urine fungal infection.

  4. The Different Effects of Family on Objective Career Success across Gender: A Test of Alternative Explanations

    Science.gov (United States)

    Kirchmeyer, Catherine

    2006-01-01

    Gender gaps in achieved rank and salary, common indicators of objective success, often are attributed to the different family roles and responsibilities of men and women. This study tested three explanations for the different effects of family on careers: that is, choice, performance, and signaling explanations. In a sample of American doctoral…

  5. A Cross-Cultural Test of the Work-Family Interface in 48 Countries

    Science.gov (United States)

    Jeffrey Hill, E.; Yang, Chongming; Hawkins, Alan J.; Ferris, Maria

    2004-01-01

    This study tests a cross-cultural model of the work-family interface. Using multigroup structural equation modeling with IBM survey responses from 48 countries (N= 25,380), results show that the same work-family interface model that fits the data globally also fits the data in a four-group model composed of culturally related groups of countries,…

  6. A new certified reference material for benzene measurement in air on a sorbent tube: development and proficiency testing

    Energy Technology Data Exchange (ETDEWEB)

    Caurant, A. [Laboratoire National de Metrologie et d' Essais, Paris (France); Universite Paris 12 et CNRS (UMR 7583), Faculte des Sciences et Technologie, Laboratoire Inter-universitaire des Systemes Atmospheriques, Unite Mixte de Recherche Universite Paris 7 (France); Lalere, B.; Schbath, M.C.; Stumpf, C.; Sutour, C.; Mace, T.; Vaslin-Reimann, S. [Laboratoire National de Metrologie et d' Essais, Paris (France); Quisefit, J.P.; Doussin, J.F. [Universite Paris 12 et CNRS (UMR 7583), Faculte des Sciences et Technologie, Laboratoire Inter-universitaire des Systemes Atmospheriques, Unite Mixte de Recherche Universite Paris 7 (France)

    2010-11-15

    A certified matrix reference material (CRM) for the measurement of benzene in ambient air has been developed at Laboratoire National de Metrologie et d'Essais. The production of these CRMs was conducted using a gravimetric method fully traceable to the International System of Units. The CRMs were prepared by sampling an accurate mass of a gaseous primary reference material of benzene, using a high-precision laminar flowmeter and a mass flow controller, with a PerkinElmer sampler filled with Carbopack trademark X sorbent. The relative standard deviations obtained for the preparation of a batch of 20 tubes loaded with 500 ng of benzene were below 0.2%. Each CRM is considered independent from the others and with its own certified value and an expanded uncertainty estimated to be within 0.5%, lower than the uncertainties of benzene CRMs already available worldwide. The stability of these materials was also established up to 12 months. These CRMs were implemented during proficiency testing, to evaluate the analytical performances of seven French laboratories involved in benzene air monitoring. (orig.)

  7. Generation of life in a test tube: Albert Szent-Gyorgyi, Bruno Straub, and the discovery of actin.

    Science.gov (United States)

    Rall, Jack A

    2018-06-01

    This is a story about a great scientist, luck, great discovery that changed the future direction of muscle research, war, a clandestine war mission, postwar politics, and an attempt to rewrite scientific history. Albert Szent-Gyorgyi, at 44 yr of age, won the Nobel Prize in 1937 for his work on vitamin C and the establishment of the groundwork of the citric acid cycle. He now wanted to investigate one of the fundamental aspects of life and settled on the study of muscle contraction. The Szent-Gyorgyi laboratory in Hungary during World War II demonstrated that contraction could be reproduced in vitro by threads consisting of just two proteins, myosin and the newly discovered protein by Bruno Straub that they called actin. Szent-Gyorgyi called seeing the contraction of these threads, which occurred in the presence of ATP and ions, "the most thrilling moment" of his scientific life. This major discovery of the generation of "life" in a test tube was totally unknown for years by the rest of the world because of the war. When the discovery was finally communicated to the world, it was not immediately accepted by all as being relevant to the physiology of muscle contraction. Nonetheless, this discovery opened up the modern phase of muscle research. Serendipity played an important role in the great discovery, and much later politics would lead to a shocking controversy around the true discoverer of actin.

  8. Comparative study of three screening tests, two microbiological tube tests, and a multi-sulphonamide ELISA kit for the detection of antimicrobial and sulphonamide residues in eggs.

    Science.gov (United States)

    Gaudin, V; Hedou, C; Rault, A; Sanders, P; Verdon, E

    2009-04-01

    The screening of antimicrobial residues in eggs is an especially important subject. Three different commercial kits for the screening of sulphonamides and other antimicrobials in eggs were validated in accordance with Decision 2002/657/EC: one enzyme-linked immunoabsorbant assay (ELISA) kit multi-sulphonamides (from RAISIO Diagnostics) and two microbiological tests (a Premi test from DSM and an Explorer kit from Zeu-Inmunotec). The false-positive rates were lower than 2% for all kits. The detection capabilities (CCbeta) have to be as low as possible for banned substances and lower than the maximum residue limit (MRL) when MRLs have been set. The sensitivity of the Premi test was better than that of the Explorer test, probably because of the dilution of the eggs before the Explorer test was used. The CCbeta values towards most of the tested sulphonamides were satisfactory with the Premi test (amoxicillin, neomycin, tylosin and erythromycin were lower than their respective MRLs. Detection capabilities for sulphonamides were much lower for the ELISA kit than for microbiological tests. The ELISA kit could be recommended for the targeted screening of sulphonamides in eggs. On the other hand, the Explorer and Premi tests could be used as wide screening tests allowing the detection of most of the antimicrobial families.

  9. Quality Control Tests on Andrographis paniculata Nees (Family ...

    African Journals Online (AJOL)

    Purpose: To characterize the aerial parts of Andrographis paniculata, a bitter Indian herb grown in Nigeria, for the purpose of quality control. Methods: The determination of bitterness value and of various physicochemical characteristics; tests for key phytochemicals; and thin layer chromatography (TLC) of the air-dried herb, ...

  10. Testing for direct genetic effects using a screening step in family-based association studies

    Directory of Open Access Journals (Sweden)

    Sharon M Lutz

    2013-11-01

    Full Text Available In genome wide association studies (GWAS, families based studies tend to have less power to detect genetic associations than population based studies, such as case-control studies. This can be an issue when testing if genes in a family based GWAS have a direct effect on the phenotype of interest or if the genes act indirectly through a secondary phenotype. When multiple SNPs are tested for a direct effect in the family based study, a screening step can be used to minimize the burden of multiple comparisons in the causal analysis. We propose a 2-stage screening step that can be incorporated into the family based association test (FBAT approach similar to the conditional mean model approach in the VanSteen-algorithm [1]. Simulations demonstrate that the type 1 error is preserved and this method is advantageous when multiple markers are tested. This method is illustrated by an application to the Framingham Heart Study.

  11. Changes in pediatric tracheostomy tubes exposed to home dishwashing.

    Science.gov (United States)

    Smolar, David E; Ho, Brian; Kent, Steven M; Hughes, C Anthony; Mettenburg, Donald; Rueggeberg, Fredrick A; Groves, Michael W

    2017-09-01

    Determine the effects of household dishwashing on Tracheostomy Tube safety. Tracheostomy tubes accumulate biofilms, which may limit their lifespan. Frequent cleaning of the tubes is a method for biofilm prevention. Cleaning practices vary widely. Some families prefer dishwashing of tubes, but its effects are currently unknown. We hypothesize that dishwashing has no significant effect on the physical properties of tracheostomy tubes and can be recommended as a safe way to clean tracheostomy tubes. Twenty 4.0 Shiley™ pediatric tracheostomy tubes were randomly assigned into dishwashed (DW) and non-dishwashed (NDW) groups, 10/group. DW tubes were subjected to 12 wash cycles. Each tube's hardness along with the surface spectra were analyzed to assess for chemical composition changes. Three cannula samples from each group were also randomly assessed with scanning-electron microscopy and scored by blinded examiners to assess for changes in surface heterogeneity. Hardness testing revealed a statistically significant difference (p = 0.0009) between the NDW and the DW group indicating increased fragility in the dishwashed tubes. Spectral analysis revealed loss of plasticizers, indicating decreased flexibility. Blinded electron microscopy scoring revealed increased surface heterogeneity in the DW group (p = 0.00007). A significant decrease in tube hardness and increased surface heterogeneity were found with dishwashing. The spectral analysis demonstrated increasing fragility. We believe these effects could potentially lead to decreased mechanical safety. With increased surface heterogeneity there is a greater potential for biofilm formation. At this time, dishwashing cannot be recommended as a tracheostomy tube cleaning method. Copyright © 2017. Published by Elsevier B.V.

  12. Serial testing of refugees for latent tuberculosis using the QuantiFERON-gold in-tube: effects of an antecedent tuberculin skin test.

    Science.gov (United States)

    Baker, Cristina A; Thomas, William; Stauffer, William M; Peterson, Phillip K; Tsukayama, Dean T

    2009-04-01

    Screening for latent tuberculosis infection (LTBI) in refugee populations immigrating to low-incidence countries remains a challenge. We assessed the characteristics of the QuantiFERON-Gold In-Tube (QFT-GIT) compared with the tuberculin skin test (TST) in 198 refugees of all ages from tuberculosis-endemic countries. Diagnostic agreement between the first QFT-GIT and simultaneous TST was 78% (kappa = 0.56) and between serial QFT-GITs was 89% (kappa = 0.76). In serial QFT-GIT testing, 70% of subjects had an increased QFT-GIT value, perhaps the result of an antecedent TST in the setting of previous TB exposure. This boosting seemed to become less prevalent with time from TST and occurred less frequently in those with negative first QFT-GIT readings. Despite small changes in the quantitative results caused by nonspecific variation and boosting, the diagnostic result of the QFT-GIT was reliable. The QFT-GIT shows the potential to replace the TST for LTBI screening in refugees from tuberculosis-endemic areas.

  13. Development of a system for monitoring and diagnosis of steam generator tubes using artificial intelligence techniques on Eddy Current Test signals

    International Nuclear Information System (INIS)

    Mesquita, Roberto Navarro de; Ting, Daniel Kao Sun; Lopez, Luis A. Negro M.; Upadhyaya, Belle R.

    2002-01-01

    New classification and feature extraction methods for steam generator tube defects are being developed by IPEN/CNEN-SP in cooperation with UTK to improve a monitoring and diagnosis system for classification and characterization of steam generator tube defects using Eddy Current Testing (ECT) signals. The first methodology being developed uses a set of feature extraction methods applied to different tube defect type ECT signals and each obtained feature vector is projected into a bi-dimensional map obtained by a Self-Organizing Map neural network. This methodology allows an optimal feature extraction method selection for the defect type classification. Other approach is being developed using tubes with different manufactured defect types which are tested using MIZ-17ET equipment with 4 sets of probes (two different diameter). A fuzzy inference system will be used to build a knowledge base for these defects. These methodology and algorithms will be integrated into an automated diagnosis system being developed with UTK, which is designed to read both on-line acquired data, as well as stored data files. These commercial software tools are the ones usually utilized in nuclear power plants. (author)

  14. Development of a system for monitoring and diagnosis of steam generator tubes using artificial intelligence techniques on Eddy Current Test signals

    Energy Technology Data Exchange (ETDEWEB)

    Mesquita, Roberto Navarro de [Instituto de Pesquisas Energeticas e Nucleares (IPEN), Sao Paulo, SP (Brazil). Centro de Monitoracao e Diagnostico]|[Sao Paulo Univ., SP (Brazil); Ting, Daniel Kao Sun [Instituto de Pesquisas Energeticas e Nucleares (IPEN), Sao Paulo, SP (Brazil). Centro de Monitoracao e Diagnostico; Cabral, Eduardo Lobo C. [Sao Paulo Univ., SP (Brazil); Lopez, Luis A. Negro M. [Faculdade de Engenharia Industrial, Sao Bernardo do Campo, SP (Brazil); Upadhyaya, Belle R. [Tennessee Univ., Knoxville, TN (United States)

    2002-07-01

    New classification and feature extraction methods for steam generator tube defects are being developed by IPEN/CNEN-SP in cooperation with UTK to improve a monitoring and diagnosis system for classification and characterization of steam generator tube defects using Eddy Current Testing (ECT) signals. The first methodology being developed uses a set of feature extraction methods applied to different tube defect type ECT signals and each obtained feature vector is projected into a bi-dimensional map obtained by a Self-Organizing Map neural network. This methodology allows an optimal feature extraction method selection for the defect type classification. Other approach is being developed using tubes with different manufactured defect types which are tested using MIZ-17ET equipment with 4 sets of probes (two different diameter). A fuzzy inference system will be used to build a knowledge base for these defects. These methodology and algorithms will be integrated into an automated diagnosis system being developed with UTK, which is designed to read both on-line acquired data, as well as stored data files. These commercial software tools are the ones usually utilized in nuclear power plants. (author)

  15. The second eddy current testing of zircaloy tube samples from the OECD Halden reactor project at Reactor Fuel Examination Facility, Tokai, JAERI

    International Nuclear Information System (INIS)

    Ohwada, Isao; Nishino, Yasuharu

    1986-07-01

    The Reactor Fuel Examination Facility in Tokai/JAERI (Japan Atomic Energy Research Institute) joined to the second round robin programme on eddy current test of the Halden/IFE. In the programme, two zircaloy tube samples with some artificial defects were provided for measurements. To clarify the locations in axial and azimuthal directions, types and dimensions of the provided artificial defects, measured signals from eddy current test were analysed in comparison with the known defects on the calibration tube. As a result, fourteen defects were determined from the measurements. Then, the location, the type and the relative dimension of them were also revealed. The results of those eddy current test are described in this paper. (author)

  16. QuantiFERON-TB Gold In-Tube as a Confirmatory Test for Tuberculin Skin Test in Tuberculosis Contact Tracing: A Noninferiority Clinical Trial.

    Science.gov (United States)

    Muñoz, Laura; Santin, Miguel; Alcaide, Fernando; Ruíz-Serrano, Maria Jesús; Gijón, Paloma; Bermúdez, Elena; Domínguez-Castellano, Angel; Navarro, María Dolores; Ramírez, Encarnación; Pérez-Escolano, Elvira; López-Prieto, María Dolores; Gutiérrez-Rodriguez, José; Anibarro, Luis; Calviño, Laura; Trigo, Matilde; Cifuentes, Carmen; García-Gasalla, Mercedes; Payeras, Antoni; Gasch, Oriol; Espasa, Mateu; Agüero, Ramon; Ferrer, Diego; Casas, Xavier; González-Cuevas, Araceli; García-Zamalloa, Alberto; Bikuña, Edurne; Lecuona, María; Galindo, Rosa; Ramírez-Lapausa, Marta; Carrillo, Raquel

    2018-01-18

    Screening strategies based on interferon-γ release assays in tuberculosis contact tracing may reduce the need for preventive therapy without increasing subsequent active disease. We conducted an open-label, randomized trial to test the noninferiority of a 2-step strategy with the tuberculin skin test (TST) followed by QuantiFERON-TB Gold In-Tube (QFT-GIT) as a confirmatory test (the TST/QFT arm) to the standard TST-alone strategy (TST arm) for targeting preventive therapy in household contacts of patients with tuberculosis. Participants were followed for 24 months after randomization. The primary endpoint was the development of tuberculosis, with a noninferiority margin of 1.5 percentage points. A total of 871 contacts were randomized. Four contacts in the TST arm and 2 in the TST/QFT arm developed tuberculosis. In the modified intention-to-treat analysis, this accounted for 0.99% in the TST arm and 0.51% in the TST/QFT arm (-0.48% difference; 97.5% confidence interval [CI], -1.86% to 0.90%); in the per-protocol analysis, the corresponding rates were 1.67% and 0.82% in the TST and TST/QFT arms, respectively (-0.85% difference; 97.5% CI, -3.14% to 1.43%). Of the 792 contacts analyzed, 65.3% in the TST arm and 42.2% in the TST/QFT arm were diagnosed with tuberculosis infection (23.1% difference; 95% CI, 16.4% to 30.0%). In low-incidence settings, screening household contacts with the TST and using QFT-GIT as a confirmatory test is not inferior to TST-alone for preventing active tuberculosis, allowing a safe reduction of preventive treatments. NCT01223534. © The Author 2017. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.

  17. Pseudohyperkalaemia in leukaemic patients: the effect of test tube type and form of transport to the laboratory.

    Science.gov (United States)

    Dastych, Milan; Cermáková, Zdenka

    2014-01-01

    The present study was aimed at determining the effect of the tube type used for primary sample collection and the manner of transport prior to assessment (either manual or by pneumatic tube) on the degree of pseudohyperkalaemia in leukaemic patients. Blood from six leukaemic patients was collected into seven primary sample tubes (Monovette®, Sarstedt): sample A, heparinized blood gas syringe (potassium reference value); sample B, plasma Li-heparin without separator gel; sample C, plasma Li-heparin with separator gel; and sample D, serum with separator gel. The primary sample tubes designated B, C and D were transported to the laboratory manually. Duplicates of the same sample tubes, B(PT), C(PT) and D(PT), were sent to the laboratory by pneumatic tube. In patients with chronic lymphocytic leukaemia (CLL), there was no increase in the concentration of potassium in samples B, C and D when compared to the reference value. Transport of the samples by pneumatic tube led to a pronounced increase in potassium concentration in samples B(PT) and C(PT), whereas there was no increase in sample D(PT) when compared to the reference value. In the patient with chronic myeloid leukaemia (CML), an increase in potassium concentration occurred in sample D and in samples B(PT), C(PT) and D(PT). A similar finding was observed in the patient with acute lymphocytic leukaemia (ALL), furthermore with an extremely high concentration of potassium in samples C and C(PT). Manual transport of non-coagulable blood (plasma Li-heparin without separator gel) to the laboratory results in the least possible artificial increase in potassium concentration in the sample.

  18. An audit of clinical service examining the uptake of genetic testing by at-risk family members.

    Science.gov (United States)

    Forrest, Laura; Delatycki, Martin; Curnow, Lisette; Gen Couns, M; Skene, Loane; Aitken, Maryanne

    2012-01-01

    The aim of this study was to investigate the uptake of genetic testing by at-risk family members for four genetic conditions: chromosomal translocations, fragile X syndrome, Huntington disease, and spinal muscular atrophy. A clinical audit was undertaken using genetics files from Genetic Health Services Victoria. Data were extracted from the files regarding the number of at-risk family members and the proportion tested. Information was also collected about whether discussion of at-risk family members and family communication during the genetic consultation was recorded. The proportion of at-risk family members who had genetic testing ranged from 11% to 18%. First-degree family members were most frequently tested and the proportion of testing decreased by degree of relatedness to the proband. Smaller families were significantly more likely to have genetic testing for all conditions except Huntington disease. Female at-risk family members were significantly more likely to have testing for fragile X syndrome. The majority of at-risk family members do not have genetic testing. Family communication is likely to influence the uptake of genetic testing by at-risk family members and therefore it is important that families are supported while communicating to ensure that at-risk family members are able to make informed decisions about genetic testing.

  19. A Combined Raindrop Aggregate Destruction Test-Settling Tube (RADT-ST Approach to Identify the Settling Velocity of Sediment

    Directory of Open Access Journals (Sweden)

    Liangang Xiao

    2015-10-01

    Full Text Available The use of sediment settling velocity based on mineral grain size distribution in erosion models ignores the effects of aggregation on settling velocity. The alternative approach, wet-sieved aggregate size distribution, on the other hand, cannot represent all destructive processes that eroded soils may experience under impacting raindrops. Therefore, without considering raindrop impact, both methods may lead to biased predictions of the redistribution of sediment and associated substances across landscapes. Rainfall simulation is an effective way to simulate natural raindrop impact under controlled laboratory conditions. However, very few methods have been developed to integrate rainfall simulation with the settling velocity of eroded sediment. This study aims to develop a new proxy, based on rainfall simulation, in order to identify the actual settling velocity distribution of aggregated sediment. A combined Raindrop Aggregate Destruction Test-Settling Tube (RADT-ST approach was developed to (1 simulate aggregate destruction under a series of simulated rainfalls; and (2 measure the actual settling velocity distribution of destroyed aggregates. Mean Weight Settling Velocity (MWSV of aggregates was used to investigate settling behaviors of different soils as rainfall kinetic energy increased. The results show the settling velocity of silt-rich raindrop impacted aggregates is likely to be underestimated by at least six times if based on mineral grain size distribution. The RADT-ST designed in this study effectively captures the effects of aggregation on settling behavior. The settling velocity distribution should be regarded as an evolving, rather than steady state parameter during erosion events. The combined RADT-ST approach is able to generate the quasi-natural sediment under controlled simulated rainfall conditions and is adequately sensitive to measure actual settling velocities of differently aggregated soils. This combined approach provides

  20. Family physicians understanding about Mantoux test: A survey from a high endemic TB country

    Directory of Open Access Journals (Sweden)

    Ali Niloufer

    2010-05-01

    Full Text Available Abstract Background Tuberculosis is a global health emergency and is a big challenge to diagnose and manage it. Family physicians being first contact health persons should be well competent to diagnose and manage the patients with tuberculosis. Aims This study was aimed to assess the level of understanding about Mantoux Test amongst Family Physicians in Karachi, Pakistan and to determine the difference of level of understanding by gender and number of tuberculosis patients seen in a month. Methods A cross sectional survey was conducted among 200 Family Physicians working in Karachi; the largest city and economic hub of Pakistan. Family Physicians who attended Continuous Medical Education sessions were approached after taking consent. Pre-tested, self administered questionnaire was filled consisting of: basic demographic characteristics, questions regarding knowledge about Mantoux Test, its application and interpretation. Data of 159 questionnaires was analyzed for percentages, as rest were incomplete. Chi square test was used to calculate the difference of understanding levels between various groups. Results Almost two thirds of respondents were males and above 35 years of age. Majority of Family Physicians were private practitioners and seeing more than five tuberculosis patients per month. Overall, a big gap was identified about the knowledge of Mantoux Test among study participants. Only 18.8% of Family Physicians secured Excellent (≥ 80% correct responses. This poor level of understanding was almost equally distributed in all comparative groups (Male = 20.8% versus Female = 15.9%; p - 0.69 and (Seen Conclusion Our study revealed an overall major deficit in understanding and interpretation of Mantoux Test amongst Family Physicians which needs to be addressed. Continues Medical Education sessions for Family Physicians should be organized in regular basis for upgrading their knowledge in this regards.

  1. Test of digital neutron–gamma discrimination with four different photomultiplier tubes for the NEutron Detector Array (NEDA)

    Energy Technology Data Exchange (ETDEWEB)

    Luo, X.L., E-mail: luo.xiaoliang@physics.uu.se [Department of Instrument Science and Technology, College of Mechatronics and Automation, National University of Defense Technology, Changsha (China); Department of Physics and Astronomy, Uppsala University, SE-75120 Uppsala (Sweden); Modamio, V. [INFN, Laboratori Nazionali di Legnaro, I-35020 Legnaro, Padova (Italy); Nyberg, J. [Department of Physics and Astronomy, Uppsala University, SE-75120 Uppsala (Sweden); Valiente-Dobón, J.J. [INFN, Laboratori Nazionali di Legnaro, I-35020 Legnaro, Padova (Italy); Nishada, Q. [Department of Physics and Astronomy, Uppsala University, SE-75120 Uppsala (Sweden); Angelis, G. de [INFN, Laboratori Nazionali di Legnaro, I-35020 Legnaro, Padova (Italy); Agramunt, J. [IFIC-CSIC, University of Valencia, Valencia (Spain); Egea, F.J. [IFIC-CSIC, University of Valencia, Valencia (Spain); Faculty of Engineering and Natural Sciences, Istanbul Sabahattin Zaim University, Istanbul (Turkey); Erduran, M.N.; Ertürk, S. [Nigde Universitesi, Fen-Edebiyat Falkültesi, Fizik Bölümü, Nigde (Turkey); France, G. de [GANIL, CEA/DSAM and CNRS/IN2P3, Bd Henri Becquerel, BP 55027, F-14076 Caen Cedex 05 (France); Gadea, A. [IFIC-CSIC, University of Valencia, Valencia (Spain); González, V. [Department of Electronic Engineering, University of Valencia, E-46071 Valencia (Spain); Hüyük, T. [IFIC-CSIC, University of Valencia, Valencia (Spain); Jaworski, G. [Faculty of Physics, Warsaw University of Technology, ul. Koszykowa 75, 00-662 Warszawa (Poland); Heavy Ion Laboratory, University of Warsaw, ul. Pasteura 5A, 02-093 Warszawa (Poland); Moszyński, M. [Heavy Ion Laboratory, University of Warsaw, ul. Pasteura 5A, 02-093 Warszawa (Poland); National Centre for Nuclear Research, A. Soltana 7, PL 05-400 Otwock-Swierk (Poland); and others

    2014-12-11

    A comparative study of the neutron–γ discrimination performance of a liquid scintillator detector BC501A coupled to four different 5 in. photomultiplier tubes (ET9390kb, R11833-100, XP4512 and R4144) was carried out. Both the Charge Comparison method and the Integrated Rise-Time method were implemented digitally to discriminate between neutrons and γ rays emitted by a {sup 252}Cf source. In both methods, the neutron–γ discrimination capabilities of the four photomultiplier tubes were quantitatively compared by evaluating their figure-of-merit values at different energy regions between 50 keVee and 1000 keVee. Additionally, the results were further verified qualitatively using time-of-flight to distinguish γ rays and neutrons. The results consistently show that photomultiplier tubes R11833-100 and ET9390kb generally perform best regarding neutron–γ discrimination with only slight differences in figure-of-merit values. This superiority can be explained by their relatively higher photoelectron yield, which indicates that a scintillator detector coupled to a photomultiplier tube with higher photoelectron yield tends to result in better neutron–γ discrimination performance. The results of this work will provide reference for the choice of photomultiplier tubes for future neutron detector arrays like NEDA.

  2. Scale model test results for an inverted U-tube steam generator with comparisons to heat transfer correlations

    International Nuclear Information System (INIS)

    Boucher, T.J.

    1987-01-01

    To provide data for assessment and development of thermal-hydraulic computer codes, bottom main feedwater-line-break transient simulations were performed in a scale model (Semiscale Mod-2C) of a pressurized water reactor (PWR) with conditions typical of a PWR (15.0 MPa primary pressure, 600 K steam generator inlet plenum fluid temperatures, 6.2 MPa secondary pressure). The state-of-the-art measurements in the scale model (Type III) steam generator allow for the determination of U-tube steam generator allow for the determination of U-tube steam generator secondary component interactions, tube bundle local radial heat transfer, and tube bundle and riser vapor void fractions for steady state and transient operations. To enhance the understanding of the observed phenomena, the component interactions, local heat fluxes, local secondary convective heat transfer coefficients and local vapor void fractions are discussed for steady state, full-power and transient operations. Comparisons between the measurement-derived secondary convective heat transfer coefficients and those predicted by a number of correlations, including the Chen correlation currently used in thermal-hydraulic computer codes, show that none of the correlations adequately predict the data and points out the need for the formulation of a new correlation based on this experimental data. The unique information presented herein should be of the interest to anyone involved in modeling inverted U-tube steam generator thermal-hydraulics for forced convection boiling/vaporization heat transfer. 5 refs., 13 figs., 1 tab

  3. Family-Supportive Organization Perceptions, Multiple Dimensions of Work-Family Conflict, and Employee Satisfaction: A Test of Model across Five Samples

    Science.gov (United States)

    Lapierre, Laurent M.; Spector, Paul E.; Allen, Tammy D.; Poelmans, Steven; Cooper, Cary L.; O'Driscoll, Michael P.; Sanchez, Juan I.; Brough, Paula; Kinnunen, Ulla

    2008-01-01

    Using samples of managers drawn from five Western countries, we tested a theoretical model linking employees' perceptions of their work environment's family-supportiveness to six different dimensions of work-family conflict (WFC), and to their job satisfaction, family satisfaction, and life satisfaction. Our results are consistent with a causal…

  4. Personal Narratives of Genetic Testing: Expectations, Emotions, and Impact on Self and Family.

    Science.gov (United States)

    Anderson, Emily E; Wasson, Katherine

    2015-01-01

    The stories in this volume shed light on the potential of narrative inquiry to fill gaps in knowledge, particularly given the mixed results of quantitative research on patient views of and experiences with genetic and genomic testing. Published studies investigate predictors of testing (particularly risk perceptions and worry); psychological and behavioral responses to testing; and potential impact on the health care system (e.g., when patients bring DTC genetic test results to their primary care provider). Interestingly, these themes did not dominate the narratives published in this issue. Rather, these narratives included consistent themes of expectations and looking for answers; complex emotions; areas of contradiction and conflict; and family impact. More narrative research on patient experiences with genetic testing may fill gaps in knowledge regarding how patients define the benefits of testing, changes in psychological and emotional reactions to test results over time, and the impact of testing on families.

  5. Routine HIV Testing of Family Members of Hospitalized Patients in Nigeria

    Directory of Open Access Journals (Sweden)

    Olusegun Busari

    2012-04-01

    Full Text Available Background: HIV testing for family members of HIV-positive patients may enhance disclosure of status of spouses, encourage family social support and improve access to HIV services. Objective was to employ the approach of routine HIV testing to determine the prevalence of HIV among family members of both HIV positive and negative patients on admission in a federal HIV treatment designated hospital in Western Nigeria Methodology: This prospective study was conducted between January 2006 and June 2009. Ethical clearance was obtained from the Research and Ethics committee of the hospital prior to the study. Informed consent was obtained from each participant. HIV testing was offered to consenting family members of HIV positive and negative patients on admission. The family members included spouses, children of patients, parents of paediatric patients and other family members. Analysis was done in frequencies and percentages Results: 162 family members of 184 patients were tested. Spouses were, 81 (50.0%; fathers, 14 (8.6%; mothers, 20 (12.3%; children, 19 (11.7% and others family members, 28 (17.3%. 151 (93.2% of testers were first timers. Majority of those tested (82.1% had post-test counseling. The overall HIV prevalence was 12.3% (20/162. HIV prevalence within different family members was 14.8% (12/81, 20% (4/20, 7.1% (1/14, 10.5% (2/19 and 3.6% (1/28 for spouses, mothers, fathers, children and others respectively.In addition, the prevalence of HIV among family members of HIV positive and negative patients was 15.6% (14/90 and 8.3% (6/72 respectively. Of 12 spouses that were positive, 7 (13.5% were HIV-discordant; and in 71.4% (5/7 of discordant couples, the spouse was positive while the patient on admission was negative. Conclusion: The results indicate that routine HIV testing of family members of patients on admission is a strategy for identification of vast number of HIV infected persons. This method is not only innovative, but also a novel

  6. Support Seeking or Familial Obligation: An Investigation of Motives for Disclosing Genetic Test Results.

    Science.gov (United States)

    Greenberg, Marisa; Smith, Rachel A

    2016-01-01

    Genetic test results reveal not only personal information about a person's likelihood of certain medical conditions but also information about the person's genetic relatives. Given the familial nature of genetic information, one's obligation to protect family members may be a motive for disclosing genetic test results, but this claim has not been methodically tested. Existing models of disclosure decision making presume self-interested motives, such as seeking social support, instead of other-interested motives, like familial obligation. This study investigated young adults' (N = 173) motives to share a genetic-based health condition, alpha-1 antitrypsin deficiency, after reading a hypothetical vignette. Results show that social support and familial obligation were both reported as motives for disclosure. In fact, some participants reported familial obligation as their primary motivator for disclosure. Finally, stronger familial obligation predicted increased likelihood of disclosing hypothetical genetic test results. Implications of these results were discussed in reference to theories of disclosure decision-making models and the practice of genetic disclosures.

  7. A multivariate family-based association test using generalized estimating equations : FBAT-GEE

    NARCIS (Netherlands)

    Lange, C; Silverman, SK; Xu, [No Value; Weiss, ST; Laird, NM

    In this paper we propose a multivariate extension of family-based association tests based on generalized estimating equations. The test can be applied to multiple phenotypes and to phenotypic data obtained in longitudinal studies without making any distributional assumptions for the phenotypic

  8. Development of a test system for the analysis of the read-out electronic cabling for the CMS drift tube chambers

    International Nuclear Information System (INIS)

    Fernandez Bedoya, C.; Montero, M.; Willmott, C.

    2004-01-01

    A test system has been developed for the analysis of the read-out electronics cabling for the CMS drift tube chambers. The read-out electronics will be placed inside some aluminium boxes, so-called Minicrates, which are going to be produced soon at CIEMAT. Due to the difficulty of detecting and repairing errors in the cables once they have been installed and recalling also to the large number of Minicrates that are going to be produced, it was decided to design and develop a test system for testing the cabling before its installation. (Author)

  9. Alternative Bio-Derived JP-8 Class Fuel and JP-8 Fuel: Flame Tube Combustor Test Results Compared using a GE TAPS Injector Configuration

    Science.gov (United States)

    Hicks, Yolanda R.; Anderson, Robert; Tedder, Sarah

    2016-01-01

    This paper presents results from tests in a NASA Glenn Research Center (GRC) flame tube facility, where a bio-derived alternate fuel was compared with JP-8 for emissions and general combustion performance. A research version of General Electric Aviation (GE) TAPS injector was used for the tests. Results include 2D, planar laser-based imaging as well as basic flow visualization of the flame. Four conditions were selected that simulate various engine power conditions relevant to NASA Fundamental Aeronautics Supersonics and Environmentally Responsible Aviation Projects were tested.

  10. Adapting and Pilot Testing a Parenting Intervention for Homeless Families in Transitional Housing.

    Science.gov (United States)

    Holtrop, Kendal; Holcomb, Jamila E

    2018-01-24

    Intervention adaptation is a promising approach for extending the reach of evidence-based interventions to underserved families. One highly relevant population in need of services are homeless families. In particular, homeless families with children constitute more than one third of the total homeless population in the United States and face several unique challenges to parenting. The purpose of this study was to adapt and pilot test a parenting intervention for homeless families in transitional housing. An established adaptation model was used to guide this process. The systematic adaptation efforts included: (a) examining the theory of change in the original intervention, (b) identifying population differences relevant to homeless families in transitional housing, (c) adapting the content of the intervention, and (d) adapting the evaluation strategy. Next, a pilot test of the adapted intervention was conducted to examine implementation feasibility and acceptability. Feasibility data indicate an intervention spanning several weeks may be difficult to implement in the context of transitional housing. Yet, acceptability of the adapted intervention among participants was consistently high. The findings of this pilot work suggest several implications for informing continued parenting intervention research and practice with homeless families in transitional housing. © 2018 Family Process Institute.

  11. Longitudinal and Integrative Tests of Family Stress Model Effects on Mexican-Origin Adolescents

    Science.gov (United States)

    White, Rebecca M. B.; Liu, Yu; Nair, Rajni L.; Tein, Jenn-Yun

    2015-01-01

    The family stress model represents a common framework through which to examine the effects of environmental stressors on adolescent adjustment. The model suggests that economic and neighborhood stressors influence youth adjustment via disruptions to parenting. Incorporating integrative developmental theory, we examined the degree to which parents’ cultural value orientations mitigated the effects of stressors on parenting disruptions and the degree to which environmental adversity qualified the effect of parenting on adolescent adjustment. We tested the hypothesized Integrative Family Stress Model longitudinally in a sample of mother-youth dyads (N = 749) and father-youth dyads (N = 467) from Mexican origin families, across three times points spanning early to middle adolescence. Providing the first longitudinal evidence of family stress mediated effects, mothers’ perceptions of economic pressure were associated with increases in adolescent externalizing symptoms five years later via intermediate increases in harsh parenting. The remaining findings supported the notion that integrative developmental theory can inform family stress model hypothesis testing that is culturally and contextually relevant for wide range of diverse families and youth. For example, fathers’ perceptions of economic pressure and neighborhood danger had important implications for adolescent internalizing, via reductions in paternal warmth, but only at certain levels of neighborhood adversity. Mothers’ familism value orientations mitigated the effects of economic pressure on maternal warmth, protecting their adolescents from experiencing developmental costs associated with environmental stressors. Results are discussed in terms of identifying how integrative developmental theory intersects with the family stress model to set diverse youth on different developmental pathways. PMID:25751100

  12. A family-based joint test for mean and variance heterogeneity for quantitative traits.

    Science.gov (United States)

    Cao, Ying; Maxwell, Taylor J; Wei, Peng

    2015-01-01

    Traditional quantitative trait locus (QTL) analysis focuses on identifying loci associated with mean heterogeneity. Recent research has discovered loci associated with phenotype variance heterogeneity (vQTL), which is important in studying genetic association with complex traits, especially for identifying gene-gene and gene-environment interactions. While several tests have been proposed to detect vQTL for unrelated individuals, there are no tests for related individuals, commonly seen in family-based genetic studies. Here we introduce a likelihood ratio test (LRT) for identifying mean and variance heterogeneity simultaneously or for either effect alone, adjusting for covariates and family relatedness using a linear mixed effect model approach. The LRT test statistic for normally distributed quantitative traits approximately follows χ(2)-distributions. To correct for inflated Type I error for non-normally distributed quantitative traits, we propose a parametric bootstrap-based LRT that removes the best linear unbiased prediction (BLUP) of family random effect. Simulation studies show that our family-based test controls Type I error and has good power, while Type I error inflation is observed when family relatedness is ignored. We demonstrate the utility and efficiency gains of the proposed method using data from the Framingham Heart Study to detect loci associated with body mass index (BMI) variability. © 2014 John Wiley & Sons Ltd/University College London.

  13. Non-operative management of right side thoracoabdominal penetrating injuries--the value of testing chest tube effluent for bile.

    Science.gov (United States)

    De Rezende Neto, João Baptista; Guimarães, Tiago Nunes; Madureira, João Lopo; Drumond, Domingos André Fernandes; Leal, Juliana Campos; Rocha, Aroldo; Oliveira, Rodrigo Guimarães; Rizoli, Sandro B

    2009-05-01

    While mandatory surgery for all thoracoabdominal penetrating injuries is advocated by some, the high rate of unnecessary operations challenges this approach. However, the consequences of intrathoracic bile remains poorly investigated. We sought to evaluate the outcome of patients who underwent non-operative management of right side thoracoabdominal (RST) penetrating trauma, and the levels of bilirubin obtained from those patients' chest tube effluent. We managed non-operatively all stable patients with a single RST penetrating injury. Chest tube effluent samples were obtained six times within (4-8 h; 12-16 h; 20-24 h; 28-32 h; 36-40 h; 48 h and 72 h) of admission for bilirubin measurement and blood for complete blood count, bilirubin, alanine (ALT) and aspartate aminotransferases (AST) assays. For comparison we studied patients with single left thoracic penetrating injury. Forty-two patients with RST injuries were included. All had liver and lung injuries confirmed by CT scans. Only one patient failed non-operative management. Chest tube bilirubin peaked at 48 h post-trauma (mean 3.3+/-4.1 mg/dL) and was always higher than both serum bilirubin (pchest tube effluent from control group (27 patients with left side thoracic trauma). Serum ALT and AST were higher in RST injury patients (ptrauma appears to be safe. Bile originating from the liver injury reaches the right thoracic cavity but does not reflect the severity of that injury. The highest concentration was found in the patient failing non-operative management. The presence of intrathoracic bile in selected patients who sustain RST penetrating trauma, with liver injury, does not preclude non-operative management. Our study suggests that monitoring chest tube effluent bilirubin may provide helpful information when managing a patient non-operatively.

  14. A prospective study of the impact of genetic susceptibility testing for BRCA1/2 or HNPCC on family relationships

    NARCIS (Netherlands)

    van Oostrom, Iris; Meijers-Heijboer, Hanne; Duivenvoorden, Hugo J.; Brocker-Vriends, Annette H. J. T.; van Asperen, Chhstl J.; Sijmons, Rolf H.; Seynaeve, Caroline; Van Gool, Arthur R.; Klijn, Jan G. M.; Riedijk, Samantha R.; van Dooren, Silvia; Tibben, Aad

    This study assessed the impact of genetic testing for cancer susceptibility on family relationships and determinants of adverse consequences for family relationships. Applicants for genetic testing of a known familial pathogenic mutation in BRCA1/2 or a HNPCC related gene (N = 271) rated the

  15. A prospective study of the impact of genetic susceptibility testing for BRCA1/2 or HNPCC on family relationships

    NARCIS (Netherlands)

    van Oostrom, Iris; Meijers-Heijboer, Hanne; Duivenvoorden, Hugo J.; Bröcker-Vriends, Annette H. J. T.; van Asperen, Christi J.; Sijmons, Rolf H.; Seynaeve, Caroline; van Gool, Arthur R.; Klijn, Jan G. M.; Riedijk, Samantha R.; van Dooren, Silvia; Tibben, Aad

    2007-01-01

    This study assessed the impact of genetic testing for cancer susceptibility on family relationships and determinants of adverse consequences for family relationships. Applicants for genetic testing of a known familial pathogenic mutation in BRCA1/2 or a HNPCC related gene (N=271) rated the

  16. A prospective study of the impact of genetic susceptibility testing for BRCA1/2 or HNPCC on family relationships.

    NARCIS (Netherlands)

    Oostrom, I.I.H. van; Meijers-Heijboer, H.; Duivenvoorden, H.J.; Brocker-Vriends, A.H.; Asperen, C.J. van; Sijmons, R.H.; Seynaeve, C.; Gool, A.R. van; Klijn, J.G.M.; Riedijk, S.R.; Dooren, S. van; Tibben, A.

    2007-01-01

    This study assessed the impact of genetic testing for cancer susceptibility on family relationships and determinants of adverse consequences for family relationships. Applicants for genetic testing of a known familial pathogenic mutation in BRCA1/2 or a HNPCC related gene (N=271) rated the

  17. Development and validation of a simulation tool dedicated to eddy current non destructive testing of tubes; Developpement d'un modele electromagnetique 3D pour la simulation du controle par Courants de Foucault de tubes en fabrication

    Energy Technology Data Exchange (ETDEWEB)

    Reboud, Ch

    2006-09-15

    Eddy current testing (ECT) technique is widely used in industrial fields such as iron and steel industry. Dedicated simulation tools provide a great assistance for the optimisation of ECT processes. CEA and the Vallourec Research Center have collaborated in order to develop a simulation tool of ECT of tubes. The volume integral method has been chosen for the resolution of Maxwell equations in a stratified medium, in order to get accurate results with a computation time short enough to carry out optimisation or inversion procedures. A fast model has been developed for the simulation of ECT of non magnetic tubes using specific external probes. New flaw geometries have been modelled: holes and notches with flat bottom. Validations of the developments, which have been integrated to the CIVA platform, have been carried out using experimental data recorded in laboratory conditions and in. industrial conditions, successively. The integral equations derived are solved using the Galerkin variant of the method of moments with pulse functions as projection functions. In order to overcome some memory limitations, other projection functions have been considered. A new discretization scheme based on non-uniform B-Splines of degree 1 or 2 has been implemented, which constitutes an original contribution to the existing literature. The decrease of the mesh size needed to get a given accuracy on the result may lead to the simulation of more complex ECT configurations. (author)

  18. Heat transfer characteristics evaluation of heat exchangers of mock-up test facility with full-scale reaction tube for HTTR hydrogen production system (Contract research)

    International Nuclear Information System (INIS)

    Shimizu, Akira; Ohashi, Hirofumi; Kato, Michio; Hayashi, Koji; Aita, Hideki; Nishihara, Tetsuo; Inaba, Yoshitomo; Takada, Shoji; Morisaki, Norihiro; Sakaki, Akihiro; Maeda, Yukimasa; Sato, Hiroyuki; Inagaki, Yoshiyuki; Hanawa, Hiromi; Fujisaki, Katsuo; Yonekawa, Hideo

    2005-06-01

    Connection of hydrogen production system by steam reforming of methane to the High Temperature Engineering Test Reactor (HTTR) of the Japan Atomic Energy Research Institute (JAERI) has been surveyed until now. Mock-up test facility of this steam reforming system with full-scale reaction tube was constructed in FY 2001 and hydrogen of 120 Nm 3 /h was successfully produced in overall performance test. Totally 7 times operational tests were performed from March 2002 to December 2004. A lot of operational test data on heat exchanges were obtained in these tests. In this report specifications and structures of steam reformer, steam superheater, steam generator, condenser, helium gas cooler, feed gas heater and feed gas superheater were described. Heat transfer correlation equations for inside and outside tube were chosen from references. Spreadsheet programs were newly made to evaluate heat transfer characteristics from measured test data such as inlet and outlet temperature pressure and flow-rate. Overall heat-transfer coefficients obtained from the experimental data were compared and evaluated with the calculated values with heat transfer correlation equation. As a result, actual measurement values of all heat exchangers gave close agreement with the calculated values with correlation equations. Thermal efficiencies of the heat exchangers were adequate as they were well accorded with design value. (author)

  19. Stress corrosion crack initiation of Zircaloy-4 cladding tubes in an iodine vapor environment during creep, relaxation, and constant strain rate tests

    Science.gov (United States)

    Jezequel, T.; Auzoux, Q.; Le Boulch, D.; Bono, M.; Andrieu, E.; Blanc, C.; Chabretou, V.; Mozzani, N.; Rautenberg, M.

    2018-02-01

    During accidental power transient conditions with Pellet Cladding Interaction (PCI), the synergistic effect of the stress and strain imposed on the cladding by thermal expansion of the fuel, and corrosion by iodine released as a fission product, may lead to cladding failure by Stress Corrosion Cracking (SCC). In this study, internal pressure tests were conducted on unirradiated cold-worked stress-relieved Zircaloy-4 cladding tubes in an iodine vapor environment. The goal was to investigate the influence of loading type (constant pressure tests, constant circumferential strain rate tests, or constant circumferential strain tests) and test temperature (320, 350, or 380 °C) on iodine-induced stress corrosion cracking (I-SCC). The experimental results obtained with different loading types were consistent with each other. The apparent threshold hoop stress for I-SCC was found to be independent of the test temperature. SEM micrographs of the tested samples showed many pits distributed over the inner surface, which tended to coalesce into large pits in which a microcrack could initiate. A model for the time-to-failure of a cladding tube was developed using finite element simulations of the viscoplastic mechanical behavior of the material and a modified Kachanov's damage growth model. The times-to-failure predicted by this model are consistent with the experimental data.

  20. Handling missing data in transmission disequilibrium test in nuclear families with one affected offspring.

    Directory of Open Access Journals (Sweden)

    Gulhan Bourget

    Full Text Available The Transmission Disequilibrium Test (TDT compares frequencies of transmission of two alleles from heterozygote parents to an affected offspring. This test requires all genotypes to be known from all members of the nuclear families. However, obtaining all genotypes in a study might not be possible for some families, in which case, a data set results in missing genotypes. There are many techniques of handling missing genotypes in parents but only a few in offspring. The robust TDT (rTDT is one of the methods that handles missing genotypes for all members of nuclear families [with one affected offspring]. Even though all family members can be imputed, the rTDT is a conservative test with low power. We propose a new method, Mendelian Inheritance TDT (MITDT-ONE, that controls type I error and has high power. The MITDT-ONE uses Mendelian Inheritance properties, and takes population frequencies of the disease allele and marker allele into account in the rTDT method. One of the advantages of using the MITDT-ONE is that the MITDT-ONE can identify additional significant genes that are not found by the rTDT. We demonstrate the performances of both tests along with Sib-TDT (S-TDT in Monte Carlo simulation studies. Moreover, we apply our method to the type 1 diabetes data from the Warren families in the United Kingdom to identify significant genes that are related to type 1 diabetes.

  1. Portuguese Family Physicians' Awareness of Diagnostic and Laboratory Test Costs: A Cross-Sectional Study.

    Directory of Open Access Journals (Sweden)

    Luísa Sá

    Full Text Available Physicians' ability to make cost-effective decisions has been shown to be affected by their knowledge of health care costs. This study assessed whether Portuguese family physicians are aware of the costs of the most frequently prescribed diagnostic and laboratory tests.A cross-sectional study was conducted in a representative sample of Portuguese family physicians, using computer-assisted telephone interviews for data collection. A Likert scale was used to assess physician's level of agreement with four statements about health care costs. Family physicians were also asked to estimate the costs of diagnostic and laboratory tests. Each physician's cost estimate was compared with the true cost and the absolute error was calculated.One-quarter (24%; 95% confidence interval: 23%-25% of all cost estimates were accurate to within 25% of the true cost, with 55% (95% IC: 53-56 overestimating and 21% (95% IC: 20-22 underestimating the true actual cost. The majority (76% of family physicians thought they did not have or were uncertain as to whether they had adequate knowledge of diagnostic and laboratory test costs, and only 7% reported receiving adequate education. The majority of the family physicians (82% said that they had adequate access to information about the diagnostic and laboratory test costs. Thirty-three percent thought that costs did not influence their decision to order tests, while 27% were uncertain.Portuguese family physicians have limited awareness of diagnostic and laboratory test costs, and our results demonstrate a need for improved education in this area. Further research should focus on identifying whether interventions in cost knowledge actually change ordering behavior, in identifying optimal methods to disseminate cost information, and on improving the cost-effectiveness of care.

  2. Portuguese Family Physicians’ Awareness of Diagnostic and Laboratory Test Costs: A Cross-Sectional Study

    Science.gov (United States)

    Sá, Luísa; Costa-Santos, Cristina; Teixeira, Andreia; Couto, Luciana; Costa-Pereira, Altamiro; Hespanhol, Alberto; Santos, Paulo; Martins, Carlos

    2015-01-01

    Background Physicians’ ability to make cost-effective decisions has been shown to be affected by their knowledge of health care costs. This study assessed whether Portuguese family physicians are aware of the costs of the most frequently prescribed diagnostic and laboratory tests. Methods A cross-sectional study was conducted in a representative sample of Portuguese family physicians, using computer-assisted telephone interviews for data collection. A Likert scale was used to assess physician’s level of agreement with four statements about health care costs. Family physicians were also asked to estimate the costs of diagnostic and laboratory tests. Each physician’s cost estimate was compared with the true cost and the absolute error was calculated. Results One-quarter (24%; 95% confidence interval: 23%–25%) of all cost estimates were accurate to within 25% of the true cost, with 55% (95% IC: 53–56) overestimating and 21% (95% IC: 20–22) underestimating the true actual cost. The majority (76%) of family physicians thought they did not have or were uncertain as to whether they had adequate knowledge of diagnostic and laboratory test costs, and only 7% reported receiving adequate education. The majority of the family physicians (82%) said that they had adequate access to information about the diagnostic and laboratory test costs. Thirty-three percent thought that costs did not influence their decision to order tests, while 27% were uncertain. Conclusions Portuguese family physicians have limited awareness of diagnostic and laboratory test costs, and our results demonstrate a need for improved education in this area. Further research should focus on identifying whether interventions in cost knowledge actually change ordering behavior, in identifying optimal methods to disseminate cost information, and on improving the cost-effectiveness of care. PMID:26356625

  3. Improvement works report on mock-up model test facility with a full-scale reaction tube for HTTR hydrogen production system (Contract research)

    International Nuclear Information System (INIS)

    Sakaki, Akihiro; Kato, Michio; Hayashi, Koji; Fujisaki, Katsuo; Aita, Hideki; Ohashi, Hirofumi; Takada, Shoji; Shimizu, Akira; Morisaki, Norihiro; Maeda, Yukimasa; Sato, Hiroyuki; Hanawa, Hiromi; Yonekawa, Hideo; Inagaki, Yoshiyuki

    2005-04-01

    In order to establish the system integration technology to connect a hydrogen production system to a high temperature gas cooled reactor; the mock-up test facility with a full-scale reaction tube for the steam reforming HTTR hydrogen production system was constructed in fiscal year 2001 and its functional test operation was performed in the year. Seven experimental test operations were performed from fiscal year 2001 to 2004. On a period of each test operation, there happened some troubles. For each trouble, the cause was investigated and the countermeasures and the improvement works were performed to succeed the experiments. The tests were successfully achieved according to plan. This report describes the improvement works on the test facility performed from fiscal year 2001 to 2004. (author)

  4. Testing one model of family role in the development of formal operations

    Directory of Open Access Journals (Sweden)

    Stepanović Ivana

    2008-01-01

    Full Text Available Contemporary authors emphasise the importance of viewing the family as a specific educational context and of studying its role in the cognitive development. In this paper, we tested the model that postulates the way in which the different ways of parental mediation and various means of the family cultural-supportive system affect the development of formal operations. We assumed that the education of parents and financial status of the family form a wider context that influences the general dimensions of family interaction (emotional exchange and democratism, but also the cultural-pedagogical status of the family, and that their connection with formal operations is mediated by the above-mentioned variables. We expected the education of parents and general dimensions of family interaction to influence the parental mediation characteristic for the development of formal operations, operationalised by CSS scale, and to mediate, via this variable, the development of that form of thinking. The direct link with formal operations is postulated in the case of variables of cultural-pedagogical status and CSS scale. The sample consists of 305 pupils aged 15 to 19. The Structural Equation Modeling was used for testing the postulated model. The results show that there is a direct influence of cultural-pedagogical status and CSS scale on formal operations, but of mother's education as well. Some relations between other predictors were confirmed, and some not, which suggests that the proposed explanatory model must be revised to some degree.

  5. Experimental programme in support of the development of the European ceramic-breeder-inside-tube test-blanket: present status and future work

    International Nuclear Information System (INIS)

    Proust, E.; Roux, N.; Flament, T.; Anzidei, L.; ENEA, Frascati; Casadio, S.; Dell'orco, G.

    1992-01-01

    Four DEMO blanket classes are under investigation within the framework of the European Test-Blanket Development Programme. One of them is featured by the use of lithium ceramic breeder pellets contained inside externally helium cooled tubes. This paper summarizes the main achievements to date of the experimental programme supporting the development of this class of blanket. It also gives an outline of the areas of the breeder material, beryllium, tritium control, and thermomechanical tests, the future work envisaged for the 92-94 period. 53 refs

  6. Attitudes toward genetic testing in childhood and reproductive decision-making for familial adenomatous polyposis.

    Science.gov (United States)

    Douma, Kirsten F L; Aaronson, Neil K; Vasen, Hans F A; Verhoef, Senno; Gundy, Chad M; Bleiker, Eveline M A

    2010-02-01

    Childhood DNA testing, prenatal diagnosis (PND) and preimplantation genetic diagnosis (PGD) are available for familial adenomatous polyposis (FAP). However, the use of PND and PGD is controversial. The purpose of this study was to investigate attitudes toward, and experiences with, childhood DNA testing, PND and PGD among members of families at high risk for FAP. In this nationwide, cross-sectional study, questionnaires were sent to individuals from families at high risk for FAP assessing attitudes toward and experiences with childhood testing, PND and PGD, as well as several sociodemographic, clinical and psychosocial variables. Of the individuals from FAP families invited to participate in the study, 525 members participated (response rate=64%). Most parents who had children who were minors (n=93) (82%) were satisfied with the DNA testing procedure. One-third of all individuals wanted DNA testing for their children before age 12. Forty percent of FAP patients indicated that the disease influenced their desire to have children. Only 15% considered termination of pregnancy for FAP acceptable. Approximately 30% of individuals with a FAP diagnosis and their partners considered PND and PGD as acceptable for themselves. A positive attitude was associated with higher levels of guilt and a positive attitude toward termination of pregnancy. Importantly, of those with FAP at childbearing age, 84% had had no previous information at all about either PND or PGD. Future efforts should be aimed at educating FAP family members about reproductive options, allowing them to make an informed choice about family planning. Routine discussion of all reproductive options with a medical specialist should be encouraged.

  7. Hydrogen production by high-temperature electrolysis of water vapor steam. Test results obtained with an electrolysis tube

    International Nuclear Information System (INIS)

    Hino, Ryutaro; Miyamoto, Yoshiaki

    1995-01-01

    High-temperature electrolysis of water vapor steam is an advanced hydrogen production process decomposing high temperature steam up to 1,000degC, which applies an electro-chemical reaction reverse to the solid oxide fuel cell. At Japan Atomic Energy Research Institute, laboratory-scale experiments have been conducted using a practical electrolysis tube with 12 electrolysis cells in order to develop heat utilization systems for high-temperature gas-cooled reactors. The electrolysis cells of which electrolyte was yttria-stabilized zirconia were formed on a porous ceramic tube in series by plasma spraying. In the experiments, water steam mixed with argon carrier gas was supplied into the electrolysis tube heated at a constant temperature regulated in the range from 850degC to 950degC, and electrolysis power was supplied by a DC power source. Hydrogen production rate increased with applied voltage and electrolysis temperature; the maximum production rate was 6.9Nl/h at 950degC. Hydrogen production rate was correlated with applied current densities on the basis of experimental data. High energy efficiency was achieved under the applied current density ranging from 80 to 100 mA/cm 2 . (author)

  8. Feeding Tubes

    Science.gov (United States)

    ... feeding therapies have been exhausted. Please review product brand and method of placement carefully with your physician ... Total Parenteral Nutrition. Resources: Oley Foundation Feeding Tube Awareness Foundation Children’s Medical Nutrition Alliance APFED’s Educational Webinar ...

  9. The Bears Family Projective Test: evaluating stories of children with emotional difficulties.

    Science.gov (United States)

    Iandolo, Giuseppe; Esposito, Gianluca; Venuti, Paola

    2012-06-01

    The aim of this study was to describe and analyze the storytelling of children with emotional difficulties. Forty children with emotional and relational difficulties (inhibited and impulsive), ages between 5.5 and 9.4 years old, were assessed by a multiaxial procedure and the bears family projective test. The bears family test is a constructive-thematic-projective method based on an anthropomorphic family of bears that children can manipulate to tell a story. The stories of 40 children without emotional difficulties (matched by IQ, socio-economic status, and gender) and 322 typically developing children, aged between four and 10 years old, were used as a reference for comparisons. Results indicated that the stories of children with emotional difficulties showed many unsolved problematic events, unclear characters, negative relationships, and negative behaviors. Unlike the stories of children without emotional difficulties, positive contents didn't prevail over negative, and there wasn't a positive compensation for negative elements.

  10. Microdischarges in DC accelerator tubes

    International Nuclear Information System (INIS)

    Eastham, D.A.; Thorn, R.

    1978-07-01

    Voltage tests on the Daresbury ceramic/titanium accelerator tube have shown that microdischarges play an important role in the conditioning process. It has been found that the voltage onset for microdischarges in a tube is dependent on the surface contamination of the electrodes and the tube geometry (in particular the tube length). This geometrical effect can be related to the trajectories of secondary ions emitted from the electrode surfaces. Sensitive diagnostic techniques have been developed to study the mass and energy distribution of ions emitted along the axis of the tube during these predischarges. The energy distribution of protons (and H - ions) can be related to the origins of the discharges in the tube. Detailed results are presented for a particular tube geometry. (author)

  11. Heat Exchanger Tube to Tube Sheet Joints Corrosion Behavior

    Directory of Open Access Journals (Sweden)

    M. Iancu

    2013-03-01

    Full Text Available Paper presents the studies made by the authors above the tube to tube sheet fittings of heat exchanger with fixed covers from hydrofining oil reforming unit. Tube fittings are critical zones for heat exchangers failures. On a device made from material tube and tube sheet at real joints dimensions were establish axial compression force and traction force at which tube is extracted from expanded joint. Were used two shapes joints with two types of fittings surfaces, one with smooth hole of tube sheet and other in which on boring surface we made a groove. From extracted expanded tube zones were made samples for corrosion tests in order to establish the corrosion rate, corrosion potential and corrosion current in working mediums such as hydrofining oil and industrial water at different temperatures. The corrosion rate values and the temperature influence are important to evaluate joints durability and also the results obtained shows that the boring tube sheet shape with a groove on hole tube shape presents a better corrosion behavior then the shape with smooth hole tube sheet.

  12. Attitudes toward genetic testing in childhood and reproductive decision-making for familial adenomatous polyposis

    NARCIS (Netherlands)

    Douma, K.F.L.; Aaronson, N.K.; Vasen, H.F.A.; Verhoef, S.; Gundy, C.M.; Bleiker, E.M.A.

    2010-01-01

    Childhood DNA testing, prenatal diagnosis (PND) and preimplantation genetic diagnosis (PGD) are available for familial adenomatous polyposis (FAP). However, the use of PND and PGD is controversial. The purpose of this study was to investigate attitudes toward, and experiences with, childhood DNA

  13. Multipoint linkage analysis and homogeneity tests in 15 Dutch X-linked retinitis pigmentosa families

    NARCIS (Netherlands)

    Bergen, A. A.; van den Born, L. I.; Schuurman, E. J.; Pinckers, A. J.; van Ommen, G. J.; Bleekers-Wagemakers, E. M.; Sandkuijl, L. A.

    1995-01-01

    Linkage analysis and homogeneity tests were carried out in 15 Dutch families segregating X-linked retinitis pigmentosa (X L R P). The study included segregation data for eight polymorphic DNA markers from the short arm of the human X chromosome. The results of both multipoint linkage analysis in

  14. Intelligence Test Scores and Birth Order among Young Norwegian Men (Conscripts) Analyzed within and between Families

    Science.gov (United States)

    Bjerkedal, Tor; Kristensen, Petter; Skjeret, Geir A.; Brevik, John I.

    2007-01-01

    The present paper reports the results of a within and between family analysis of the relation between birth order and intelligence. The material comprises more than a quarter of a million test scores for intellectual performance of Norwegian male conscripts recorded during 1984-2004. Conscripts, mostly 18-19 years of age, were born to women for…

  15. Rapid Detection of the Chlamydiaceae and Other Families in the Order Chlamydiales: Three PCR Tests

    Science.gov (United States)

    Everett, Karin D. E.; Hornung, Linda J.; Andersen, Arthur A.

    1999-01-01

    Few identification methods will rapidly or specifically detect all bacteria in the order Chlamydiales, family Chlamydiaceae. In this study, three PCR tests based on sequence data from over 48 chlamydial strains were developed for identification of these bacteria. Two tests exclusively recognized the Chlamydiaceae: a multiplex test targeting the ompA gene and the rRNA intergenic spacer and a TaqMan test targeting the 23S ribosomal DNA. The multiplex test was able to detect as few as 200 inclusion-forming units (IFU), while the TaqMan test could detect 2 IFU. The amplicons produced in these tests ranged from 132 to 320 bp in length. The third test, targeting the 23S rRNA gene, produced a 600-bp amplicon from strains belonging to several families in the order Chlamydiales. Direct sequence analysis of this amplicon has facilitated the identification of new chlamydial strains. These three tests permit ready identification of chlamydiae for diagnostic and epidemiologic study. The specificity of these tests indicates that they might also be used to identify chlamydiae without culture or isolation. PMID:9986815

  16. Work-family conflict, locus of control, and women's well-being: tests of alternative pathways.

    Science.gov (United States)

    Noor, Noraini M

    2002-10-01

    The author tested for the 3 possible pathways (i.e., direct, moderator, and mediator effects) in which locus of control can influence the relationship between work-family conflict and well-being. The author predicted that work-family conflict would be negatively correlated with well-being. In a sample of 310 Malaysian employed women with families, work-family conflict was a significant predictor of both job satisfaction and distress--negatively related to job satisfaction and positively related to symptoms of distress. More important, the results provided support for the effects of all 3 pathways of control on the relationship between work-family conflict and well-being, depending on the outcome measure: For job satisfaction, locus of control had direct effects, acted as a partial mediator, and played a significant moderating role. In contrast, only the direct effect of locus of control predicted distress. The author discusses those findings with reference to the literature on work-family conflict, locus of control, and the issue of stress-distress specificity.

  17. Inter-embodiment and the experience of genetic testing for familial hypercholesterolaemia.

    Science.gov (United States)

    Jenkins, Nicholas; Lawton, Julia; Douglas, Margaret; Hallowell, Nina

    2013-05-01

    In this article we explore the concept of inter-embodiment and its potential for advancing sociological research into illness biography and genetic identity. Inter-embodiment theory views embodied knowledge as produced through relations between bodies, as opposed to originating from within the body or as the product of relations between disembodied selves. Drawing on a qualitative study in which we interviewed 38 individuals about their experiences of discovering they had high cholesterol and undergoing genetic testing for familial hypercholesterolaemia (FH), we discuss how their narratives may be understood from an inter-embodiment perspective. The participants frequently talked at length about their family histories of high cholesterol and cardiovascular disease. Through these accounts, we develop the concept of the family corpus in order to highlight the role body networks play in shaping lay constructions of genetic identity and a familial disease biography. The notion of a family corpus, we argue, is useful in understanding why genetic testing for FH was experienced as either biographical re-enforcement or as biographical disruption. We conclude by discussing the implications of our findings for future sociological research into illness biography and genetic identity. © 2012 The Authors. Sociology of Health & Illness © 2012 Foundation for the Sociology of Health & Illness/Blackwell Publishing Ltd.

  18. Steam generator tube extraction

    International Nuclear Information System (INIS)

    Delorme, H.

    1985-05-01

    To enable tube examination on steam generators in service, Framatome has now developed a process for removing sections of steam generator tubes. Tube sections can be removed without being damaged for treating the tube section expanded in the tube sheet

  19. Development and validation of the Computerized Family Relation Test (CFRT for children

    Directory of Open Access Journals (Sweden)

    Ilona eSkoczeń

    2015-11-01

    Full Text Available The aim of the present study was to develop and investigate the psychometric properties of the Computerized Family Relations Test (CFRT for children. This test assesses the quality of family relationships with the mother and father from a child’s perspective. The CFRT consists of six scales relating to control (Restrictiveness and Justice, and support (Affection, Vulnerability, Acknowledgement, and Trust within the family relationships. CFRT is an innovative approach to the Dutch Nijmegen Family Relations Test (NFRT developed by Oud and Welzen (1989. The administration of the test has been computerized and graphical representations of female and male silhouettes were included to facilitate the child’s parental identification. In total, 404 primary school children, aged 8 to 13 years (M = 11.0; SD = 1.17, took part in this study. The CFRT’s reliability was assessed by McDonald’s omega coefficients, and ranged from .71 to .86, except for Vulnerability which achieved the lowest reliability.57 for mothers’ ratings and .56 for fathers’ ratings. The test-retest procedure revealed higher stability for the ratings on father-child relationships of .71 compared to mother-child relationships of .67. Confirmatory factor analysis indicated that a six-factor model provided an adequate fit. Measurement invariance across the children’s assessments of the quality of family relationships was achieved. The construct validity of CFRT was assessed by examining differences in the child’s ratings of the relationships with the mother and father, the child’s gender, and associations of CFRT scales with other variables such as depression, anxiety symptoms, and prosocial behavior.

  20. Development and Validation of the Computerized Family Relations Test for Children.

    Science.gov (United States)

    Skoczń, Ilona; Cieciuch, Jan; Oud, Johan H L; Welzen, Kai

    2015-01-01

    The aim of the present study was to develop and investigate the psychometric properties of the Computerized Family Relations Test (CFRT) for children. This test assesses the quality of family relationships with the mother and father from a child's perspective. The CFRT consists of six scales relating to control (Restrictiveness and Justice), and support (Affection, Vulnerability, Acknowledgment, and Trust) within the family relationships. CFRT is an innovative approach to the Dutch Nijmegen Family Relations Test (NFRT) developed by Oud and Welzen (1989). The administration of the test has been computerized and graphical representations of female and male silhouettes were included to facilitate the child's parental identification. In total, 404 primary school children, aged 8 to 13 years (M = 11.0; SD = 1.17), took part in this study. The CFRT's reliability was assessed by McDonald's omega coefficients, and ranged from 0.71 to 0.86, except for Vulnerability which achieved the lowest reliability 0.57 for mothers' ratings and 0.56 for fathers' ratings. The test-retest procedure revealed higher stability for the ratings on father-child relationships of 0.71 compared to mother-child relationships of 0.67. Confirmatory factor analysis indicated that a six-factor model provided an adequate fit. Measurement invariance across the children's assessments of the quality of family relationships was achieved. The construct validity of CFRT was assessed by examining differences in the child's ratings of the relationships with the mother and father, the child's gender, and associations of CFRT scales with other variables such as depression, anxiety symptoms, and prosocial behavior.

  1. Test and Analysis of Tube Component of Electron Beam Machine (EBM) 350 keV/10 m A

    International Nuclear Information System (INIS)

    Darsono; Suprapto; Rany Saptaaji

    2003-01-01

    Tube component is the one of the local component that is designed and constructed using local materials in the Center of Advanced Technology Research and Development, and used mainly for vacuum chamber of EBM vacuum system. Gas load, product gases from out gassing process, permeation, evaporation and leakage, are factors that can affect the vacuum level of the vacuum chamber. By baking out the vacuum chamber, the releasing process from inside and wall surface will be faster, so that the out gassing and permeation rate will increase. By applying baked out process the tube having better vacuum performance were obtained. From the calculation results for the vacuum level chamber having volume of 9,859 liter and surface area of 4004,45 cm 2 , without baking out the out gassing rate (Q D ) was 4,644 x 10 -6 Torr liter/sec., permeation (Q P ) was 4,923 x 10 -6 Torr liter/sec., leakage (Q L ) was 1,691 x 10 -9 Torr liter/sec, gas load (Q G ) was 9,568 x 10 -6 Torr liter/sec. By baking out at 104,3 o C we obtained (Q D ) 2,276 x 10 -5 Torr liter/sec, (Q P ) 1,831 x 10 -5 Torr liter/sec, (Q L ) 3,161 x 10 -9 Torr liter/sec, and (Q G ) 4,108 x 10 -5 Torr liter/sec. The experimental results indicated that the final vacuum level which can be obtained the tube component without baking out was 3.375 x 10 -6 Torr in 5.33 hours, and with baking out at 104,3 o C the vacuum level was 2,25 x 10 -6 Torr in 4,25 hours. Whereas the experimental results of vacuum components in EBM system to be obtained the vacuum were 3,1 x 10 -6 mbar (2,33.10 -6 Torr). Those result indicated that the tube components fulfill the requirement to be used for the vacuum chamber component in the vacuum system of EBM. (author)

  2. Evaluation of the educational technology "Caring for dependent people" by family caregivers in changes and transfers of patients and tube feeding.

    Science.gov (United States)

    Landeiro, Maria José Lumini; Peres, Heloísa Helena Ciqueto; Martins, Teresa Vieira

    2016-08-18

    to assess the contributions of interactive educational technology "Caring for Dependent People" in the development of knowledge to family caregivers of dependent people in a household context and their satisfaction in its use. quasi-experimental study, not randomized, of the before and after type, with a convenience sample of 65 family caregivers, from two Medicine services of a hospital in Porto, Portugal. The Control Group consisted of 33 family caregivers and the Experimental Group of 32, identified by consecutive sampling. The experimental group had access to educational technology at home. Data were collected by socio-demographic, satisfaction and evaluation of knowledge questionnaire, about how to feed by nasogastric tube, positioning and transferring the dependent person. The assessment in both groups had two moments: initial, during hospitalization and one month after discharge. the experimental group had a larger increase in knowledge related to the use of the educational technology. In the control group the knowledge did not differ in the two evaluation time points. these results confirm the improvement of interactive educational technologies and in the training of family caregivers to care for dependents. This technology successfully met the technical quality and learning needs of caregivers, and was considered easy and stimulating. avaliar os contributos da tecnologia educacional interativa "Cuidar de Pessoas Dependentes" no desenvolvimento de conhecimentos aos familiares cuidadores de pessoas dependentes, no contexto domiciliário e a satisfação no seu uso. estudo quasi-experimental, não randomizado, do tipo antes e depois, com amostra de conveniência constituída por 65 familiares cuidadores, de dois Serviços de Medicina de um hospital do Porto, Portugal. O Grupo Controle foi constituído por 33 familiares cuidadores e o Grupo Experimental por 32, identificados por amostragem consecutiva. O grupo experimental teve Acesso à tecnologia educacional

  3. PedGenie: meta genetic association testing in mixed family and case-control designs

    Directory of Open Access Journals (Sweden)

    Allen-Brady Kristina

    2007-11-01

    Full Text Available Abstract Background- PedGenie software, introduced in 2006, includes genetic association testing of cases and controls that may be independent or related (nuclear families or extended pedigrees or mixtures thereof using Monte Carlo significance testing. Our aim is to demonstrate that PedGenie, a unique and flexible analysis tool freely available in Genie 2.4 software, is significantly enhanced by incorporating meta statistics for detecting genetic association with disease using data across multiple study groups. Methods- Meta statistics (chi-squared tests, odds ratios, and confidence intervals were calculated using formal Cochran-Mantel-Haenszel techniques. Simulated data from unrelated individuals and individuals in families were used to illustrate meta tests and their empirically-derived p-values and confidence intervals are accurate, precise, and for independent designs match those provided by standard statistical software. Results- PedGenie yields accurate Monte Carlo p-values for meta analysis of data across multiple studies, based on validation testing using pedigree, nuclear family, and case-control data simulated under both the null and alternative hypotheses of a genotype-phenotype association. Conclusion- PedGenie allows valid combined analysis of data from mixtures of pedigree-based and case-control resources. Added meta capabilities provide new avenues for association analysis, including pedigree resources from large consortia and multi-center studies.

  4. On Wasserstein Two-Sample Testing and Related Families of Nonparametric Tests

    Directory of Open Access Journals (Sweden)

    Aaditya Ramdas

    2017-01-01

    Full Text Available Nonparametric two-sample or homogeneity testing is a decision theoretic problem that involves identifying differences between two random variables without making parametric assumptions about their underlying distributions. The literature is old and rich, with a wide variety of statistics having being designed and analyzed, both for the unidimensional and the multivariate setting. Inthisshortsurvey,wefocusonteststatisticsthatinvolvetheWassersteindistance. Usingan entropic smoothing of the Wasserstein distance, we connect these to very different tests including multivariate methods involving energy statistics and kernel based maximum mean discrepancy and univariate methods like the Kolmogorov–Smirnov test, probability or quantile (PP/QQ plots and receiver operating characteristic or ordinal dominance (ROC/ODC curves. Some observations are implicit in the literature, while others seem to have not been noticed thus far. Given nonparametric two-sample testing’s classical and continued importance, we aim to provide useful connections for theorists and practitioners familiar with one subset of methods but not others.

  5. A Comparative Test of Work-Family Conflict Models and Critical Examination of Work-Family Linkages

    Science.gov (United States)

    Michel, Jesse S.; Mitchelson, Jacqueline K.; Kotrba, Lindsey M.; LeBreton, James M.; Baltes, Boris B.

    2009-01-01

    This paper is a comprehensive meta-analysis of over 20 years of work-family conflict research. A series of path analyses were conducted to compare and contrast existing work-family conflict models, as well as a new model we developed which integrates and synthesizes current work-family theory and research. This new model accounted for 40% of the…

  6. A method of multi-crack shape identification from eddy current testing signals of steam generator tubes including support plates as noise sources

    International Nuclear Information System (INIS)

    Nagaya, Yoshiaki; Endo, Hisashi; Takagi, Toshiyuki; Uchimoto, Tetsuya

    2005-01-01

    This paper deals with identifying multiple cracks from eddy current testing (ECT) signals obtained in a steam generator tube with a support plate and deposits. Assume two-dimensionally scanned ECT signals to be a picture image, then the signal processing by a multi-frequency technique eliminates noise caused by the support plate and deposits. A template matching with help of genetic algorithms detects number and positions of cracks from the image after the signal processing. Inverse analysis estimates the crack profile based on the predicted position of cracks. The number and positions of the cracks are sufficiently well predicted. Crack shape reconstructions are achieved with a satisfactory degree of accuracy. (author)

  7. Scale-up of counter-current chromatography: demonstration of predictable isocratic and quasi-continuous operating modes from the test tube to pilot/process scale.

    Science.gov (United States)

    Sutherland, Ian; Hewitson, Peter; Ignatova, Svetlana

    2009-12-11

    Predictable scale-up from test tube derived distribution ratios and analytical-scale sample loading optimisation is demonstrated using a model sample system of benzyl alcohol and p-cresol in a heptane:ethyl acetate:methanol:water phase system with the new 18 L Maxi counter-current chromatography centrifuge. The versatility of having a liquid stationary phase with its high loading capacity and flexible operating modes is demonstrated at two different scales by separating and concentrating target compounds using a mixture of caffeine, vanillin, naringenin and carvone using a quasi-continuous technique called intermittent counter-current extraction.

  8. Streak tube development

    International Nuclear Information System (INIS)

    Hinrichs, C.K.; Estrella, R.M.

    1979-01-01

    A research program for the development of a high-speed, high-resolution streak image tube is described. This is one task in the development of a streak camera system with digital electronic readout, whose primary application is for diagnostics in underground nuclear testing. This program is concerned with the development of a high-resolution streak image tube compatible with x-ray input and electronic digital output. The tube must be capable of time resolution down to 100 psec and spatial resolution to provide greater than 1000 resolution elements across the cathode (much greater than presently available). Another objective is to develop the capability to make design changes in tube configurations to meet different experimental requirements. A demountable prototype streak tube was constructed, mounted on an optical bench, and placed in a vacuum system. Initial measurements of the tube resolution with an undeflected image show a resolution of 32 line pairs per millimeter over a cathode diameter of one inch, which is consistent with the predictions of the computer simulations. With the initial set of unoptmized deflection plates, the resolution pattern appeared to remain unchanged for static deflections of +- 1/2-inch, a total streak length of one inch, also consistent with the computer simulations. A passively mode-locked frequency-doubled dye laser is being developed as an ultraviolet pulsed light source to measure dynamic tube resolution during streaking. A sweep circuit to provide the deflection voltage in the prototype tube has been designed and constructed and provides a relatively linear ramp voltage with ramp durations adjustable between 10 and 1000 nsec

  9. Experimental analysis of solar thermal integrated MD system for cogeneration of drinking water and hot water for single family villa in dubai using flat plate and evacuated tube solar collectors

    DEFF Research Database (Denmark)

    Asim, Muhammad; Imran, Muhammad; Leung, Michael K.H.

    2017-01-01

    This paper presents the experimental analysis performed on solar thermal integrated membrane distillation (MD) system using flat plate and evacuated tube collectors. The system will be utilized for cogeneration of drinking water and domestic hot water for single family in Dubai comprising of four...... to five members. Experiments have been performed in Ras Al Khaimah Research and Innovation Centre (RAKRIC) facility. The experimental setup has been installed to achieve the required production of 15–25 L/d of drinking water and 250 L/d of hot water for domestic purposes. Experiments have been performed...

  10. Qualification of the testing process by a new rotating probe for the 900 MW PWR steam generators tubes

    International Nuclear Information System (INIS)

    Caston, D.

    2001-01-01

    In 1997, EDF invites bids for the development of eddy current probes, in order to better control the steam generator tubes rolling zone of the PWR. After examination of the response, EDF accepted a prototype of a rotating probe. The EDF specifications of the new steam generators contract, fix the inspection performance and rhythm of the rotating probe, which implements two different technic: the STL (long rotating prob)e for the detection and characterization of longitudinal defects; the STT (transverse rotating probe) for the detection and characterization of circumferential defects. The new rotating probe should not increase the control time. Two new equipments have been developed to implement this new probe: a new support and a software of online inspection with data processing and analyzing. Abstract only. (A.L.B.)

  11. Ear Tubes

    Science.gov (United States)

    ... of the ear drum or eustachian tube, Down Syndrome, cleft palate, and barotrauma (injury to the middle ear caused by a reduction of air pressure, ... specialist) may be warranted if you or your child has experienced repeated ... fluid in the middle ear, barotrauma, or have an anatomic abnormality that ...

  12. In service inspection for steam generator tubes

    International Nuclear Information System (INIS)

    Comby, R.; Eyrolles, Ph.

    1988-01-01

    In this paper the authors show the means putting in place for examination of steam generators tubes. These means (eddy current probes, ultrasonic testing) associated with a knowledge on degradation phenomena allow mapping controlled tubes and limiting undesirable obturations [fr

  13. Steam generator tube integrity program

    International Nuclear Information System (INIS)

    Dierks, D.R.; Shack, W.J.; Muscara, J.

    1996-01-01

    A new research program on steam generator tubing degradation is being sponsored by the U.S. Nuclear Regulatory Commission (NRC) at Argonne National Laboratory. This program is intended to support a performance-based steam generator tube integrity rule. Critical areas addressed by the program include evaluation of the processes used for the in-service inspection of steam generator tubes and recommendations for improving the reliability and accuracy of inspections; validation and improvement of correlations for evaluating integrity and leakage of degraded steam generator tubes, and validation and improvement of correlations and models for predicting degradation in steam generator tubes as aging occurs. The studies will focus on mill-annealed Alloy 600 tubing, however, tests will also be performed on replacement materials such as thermally-treated Alloy 600 or 690. An overview of the technical work planned for the program is given

  14. Testing the theory of holism: A study of family systems and adolescent health

    Directory of Open Access Journals (Sweden)

    Valerie Michaelson

    2016-12-01

    Full Text Available Holism is an ancient theory that can be applied contemporarily to adolescent health and its determinants. This theory suggests that there is value in considering factors that influence health together as integrated wholes, in addition to consideration of individual components. Characteristics of families are fundamental determinants of health and provide opportunity for exploration of this theory. In a “proof-of-concept” analysis we therefore: (1 developed a multidimensional, composite (holistic measure to be used to characterize family systems; and (2 related this measure and its individual components to adolescent health outcomes, in order to test the theory of holism. Cross-sectional analyses of survey reports from the 2014 Canadian Health Behaviour in School-aged Children study (weighted n = 19,333 were performed. Factor analysis was used to confirm the psychometric properties of the holistic measure to describe a family system (the “holistic measure”. Associations between this holistic measure, its individual components, and various indicators of health were examined descriptively and using binomial regression. The holistic measure (4 items, α = 0.62; RMSEA = .04; SRMR = 0.01; AGFI = 0.99 included components describing family: material wealth, meal practices, neighbourhood social capital, and social connections. It was consistently associated with various health behaviours, and social and emotional health outcomes. In 22/24 comparisons, this holistic measure related to positive health outcomes more strongly than did its individual components; for negative health outcomes this occurred in 20/24 comparisons. Study findings suggest that it is possible to assess family systems holistically. Such systems are strongly associated with adolescent health outcomes, and there is etiological and theoretical value in considering family systems as integrated wholes.

  15. Non-destructive controls in the steel tube industry

    International Nuclear Information System (INIS)

    Mondot, J.

    1978-01-01

    The main non-destructive control methods in the tube industry are reviewed: eddy currents, particularly well adapted to small tubes; magnetoscopic testing for weldless tubes; ultrasonic waves widely used for thick weldless tubes and weldings; radiography, to examine tube ends and the known questionable zones; measure of diameters by laser [fr

  16. Characterization of tube support alloys

    International Nuclear Information System (INIS)

    Vaia, A.R.

    1985-01-01

    The involvement and relationship of carbon steel corrosion products in the tube denting phenomenon promoted an intensive research effort to: 1) understand, reproduce, and arrest the denting process, and 2) evaluate alternative tube support materials to provide additional corrosion resistance. The paper summarizes a corrosion testing program for the verification of type 405 stainless steel under acid or all volatile treatment conditions

  17. Application of Barcoding to Reduce Error of Patient Identification and to Increase Patient's Information Confidentiality of Test Tube Labelling in a Psychiatric Teaching Hospital.

    Science.gov (United States)

    Liu, Hsiu-Chu; Li, Hsing; Chang, Hsin-Fei; Lu, Mei-Rou; Chen, Feng-Chuan

    2015-01-01

    Learning from the experience of another medical center in Taiwan, Kaohsiung Municipal Kai-Suan Psychiatric Hospital has changed the nursing informatics system step by step in the past year and a half . We considered ethics in the original idea of implementing barcodes on the test tube labels to process the identification of the psychiatric patients. The main aims of this project are to maintain the confidential information and to transport the sample effectively. The primary nurses had been using different work sheets for this project to ensure the acceptance of the new barcode system. In the past two years the errors in the blood testing process were as high as 11,000 in 14,000 events per year, resulting in wastage of resources. The actions taken by the nurses and the new barcode system implementation can improve the clinical nursing care quality, safety of the patients, and efficiency, while decreasing the cost due to the human error.

  18. Electron tube

    Science.gov (United States)

    Suyama, Motohiro [Hamamatsu, JP; Fukasawa, Atsuhito [Hamamatsu, JP; Arisaka, Katsushi [Los Angeles, CA; Wang, Hanguo [North Hills, CA

    2011-12-20

    An electron tube of the present invention includes: a vacuum vessel including a face plate portion made of synthetic silica and having a surface on which a photoelectric surface is provided, a stem portion arranged facing the photoelectric surface and made of synthetic silica, and a side tube portion having one end connected to the face plate portion and the other end connected to the stem portion and made of synthetic silica; a projection portion arranged in the vacuum vessel, extending from the stem portion toward the photoelectric surface, and made of synthetic silica; and an electron detector arranged on the projection portion, for detecting electrons from the photoelectric surface, and made of silicon.

  19. Advanced evacuated tube collectors

    Science.gov (United States)

    Schertz, W. W.; Hull, J. R.; Winston, R.; Ogallagher, J.

    1985-04-01

    The essence of the design concept for these new collectors is the integration of moderate levels of nonimaging concentration inside the evacuated tube itself. This permanently protects the reflection surfaces and allows the use of highly reflecting front surface mirrors with reflectances greater than 95%. Previous fabrication and long term testing of a proof-of-concept prototype has established the technical success of the concept. Present work is directed toward the development of a manufacturable unit that will be suitable for the widest possible range of applications. Design alternatives include scaling up the original prototype's tube diameter from 5 cm to 10 cm, using an internal shaped metal concentrating reflector, using a variety of profile shapes to minimize so-called gap losses and accommodate both single ended and double-ended flow geometries, and allowing the use of heat pipes for the absorber tube.

  20. Protocol for a randomized controlled trial testing the impact of feedback on familial risk of chronic diseases on family-level intentions to participate in preventive lifestyle behaviors

    Directory of Open Access Journals (Sweden)

    Carlene J. Wilson

    2016-09-01

    Full Text Available Abstract Background Common disease risk clusters in families due to shared genetics, exposure to environmental risk factors, and because many health behaviours are established and maintained in family environments. This randomised controlled trial will test whether the provision of a family health history (FHH risk assessment tool increases intentions and engagement in health behaviors. Message distribution and collective behavior change within family networks will be mapped using social network analysis. The relative intervention impact will be compared between families from different ethnic backgrounds. Methods One hundred and fifty mothers (50 Anglo-Australian, 50 Italian-Australian, 50 Vietnamese-Australian will be recruited, with four or more other family members across three generations, including a child (aged 10–18 years. Each family is randomly assigned to intervention or control. At baseline and 6-month follow-up, all participants complete surveys to assess dietary and physical activity intentions and behaviors, attitudes towards food, and perceived disease risk. Intervention families receive a visual pedigree detailing their FHH of diabetes, heart disease, breast and bowel cancer, a health education workbook to ascertain members’ disease risk (i.e. average or above average risk, and screening and primary prevention recommendations. After completion of follow-up assessments, controls will receive their pedigree and workbook. The primary hypothesis is that attitudes and lifestyle behaviors will improve more within families exposed to FHH feedback, although the extent of this improvement may vary between families from different ethnic backgrounds. Additionally, the extent of improvement in the treatment group will be moderated by the level of family disease risk, with above-average risk leading to greater improvement. A secondary aim will explore different family members’ roles in message distribution and collective responses to

  1. Protocol for a randomized controlled trial testing the impact of feedback on familial risk of chronic diseases on family-level intentions to participate in preventive lifestyle behaviors.

    Science.gov (United States)

    Wilson, Carlene J; de la Haye, Kayla; Coveney, John; Hughes, Donna L; Hutchinson, Amanda; Miller, Caroline; Prichard, Ivanka; Ward, Paul; Koehly, Laura M

    2016-09-13

    Common disease risk clusters in families due to shared genetics, exposure to environmental risk factors, and because many health behaviours are established and maintained in family environments. This randomised controlled trial will test whether the provision of a family health history (FHH) risk assessment tool increases intentions and engagement in health behaviors. Message distribution and collective behavior change within family networks will be mapped using social network analysis. The relative intervention impact will be compared between families from different ethnic backgrounds. One hundred and fifty mothers (50 Anglo-Australian, 50 Italian-Australian, 50 Vietnamese-Australian) will be recruited, with four or more other family members across three generations, including a child (aged 10-18 years). Each family is randomly assigned to intervention or control. At baseline and 6-month follow-up, all participants complete surveys to assess dietary and physical activity intentions and behaviors, attitudes towards food, and perceived disease risk. Intervention families receive a visual pedigree detailing their FHH of diabetes, heart disease, breast and bowel cancer, a health education workbook to ascertain members' disease risk (i.e. average or above average risk), and screening and primary prevention recommendations. After completion of follow-up assessments, controls will receive their pedigree and workbook. The primary hypothesis is that attitudes and lifestyle behaviors will improve more within families exposed to FHH feedback, although the extent of this improvement may vary between families from different ethnic backgrounds. Additionally, the extent of improvement in the treatment group will be moderated by the level of family disease risk, with above-average risk leading to greater improvement. A secondary aim will explore different family members' roles in message distribution and collective responses to risk using social network approaches and to compare

  2. An Efficient Test for Gene-Environment Interaction in Generalized Linear Mixed Models with Family Data.

    Science.gov (United States)

    Mazo Lopera, Mauricio A; Coombes, Brandon J; de Andrade, Mariza

    2017-09-27

    Gene-environment (GE) interaction has important implications in the etiology of complex diseases that are caused by a combination of genetic factors and environment variables. Several authors have developed GE analysis in the context of independent subjects or longitudinal data using a gene-set. In this paper, we propose to analyze GE interaction for discrete and continuous phenotypes in family studies by incorporating the relatedness among the relatives for each family into a generalized linear mixed model (GLMM) and by using a gene-based variance component test. In addition, we deal with collinearity problems arising from linkage disequilibrium among single nucleotide polymorphisms (SNPs) by considering their coefficients as random effects under the null model estimation. We show that the best linear unbiased predictor (BLUP) of such random effects in the GLMM is equivalent to the ridge regression estimator. This equivalence provides a simple method to estimate the ridge penalty parameter in comparison to other computationally-demanding estimation approaches based on cross-validation schemes. We evaluated the proposed test using simulation studies and applied it to real data from the Baependi Heart Study consisting of 76 families. Using our approach, we identified an interaction between BMI and the Peroxisome Proliferator Activated Receptor Gamma ( PPARG ) gene associated with diabetes.

  3. Chest tube insertion

    Science.gov (United States)

    Chest drainage tube insertion; Insertion of tube into chest; Tube thoracostomy; Pericardial drain ... Be careful there are no kinks in your tube. The drainage system should always sit upright and be placed ...

  4. [The genotype-based haplotype relative risk and transmission disequilibrium test analyses of familial febrile convulsions].

    Science.gov (United States)

    Qi, Y; Wu, X; Guo, Z; Zhang, J; Pan, H; Li, M; Bao, X; Peng, J; Zou, L; Lin, Q

    1999-10-01

    To confirm the linkage of familial febrile convulsions to the short arm of chromosome 6(6p) or the long arm of chromosome 8(8q). The authors finished genotyping of Pst I locus on the coding region of heat shock protein (HSP) 70, 5'untranslated region of HSP70-1, 3' untranslated region of HSP70-2, D8S84 and D8S85. The data were processed by the genotype-based haplotype relative risk(GHRR) and transmission disequilibrium test(TDT) methods in PPAP. Some signs of association and disequilibrium between D8S85 and FC were shown by GHRR and TDT. A suspect linkage of familial febrile convulsions to the long arm of chromosome 8 has been proposed.

  5. Failure analysis of boiler tube

    International Nuclear Information System (INIS)

    Mehmood, K.; Siddiqui, A.R.

    2007-01-01

    Boiler tubes are energy conversion components where heat energy is used to convert water into high pressure superheated steam, which is then delivered to a turbine for electric power generation in thermal power plants or to run plant and machineries in a process or manufacturing industry. It was reported that one of the tubes of a fire-tube boiler used in a local industry had leakage after the formation of pits at the external surface of the tube. The inner side of the fire tube was working with hot flue gasses with a pressure of 10 Kg/cm/sup 2/ and temperature 225 degree C. The outside of the tube was surrounded by feed water. The purpose of this study was to determine the cause of pits developed at the external surface of the failed boiler tube sample. In the present work boiler tube samples of steel grade ASTM AI61/ASTM A192 were analyzed using metallographic analysis, chemical analysis, and mechanical testing. It was concluded that the appearance of defects on the boiler tube sample indicates cavitation type corrosion failure. Cavitation damage superficially resembled pitting, but surface appeared considerably rougher and had many closely spaced pits. (author)

  6. Stress, depression and medication nonadherence in diabetes: test of the exacerbating and buffering effects of family support.

    Science.gov (United States)

    Mayberry, Lindsay Satterwhite; Egede, Leonard E; Wagner, Julie A; Osborn, Chandra Y

    2015-04-01

    Stressors and depressive symptoms have been associated with medication nonadherence among adults with type 2 diabetes (T2DM). We tested whether these associations were exacerbated by obstructive family behaviors or buffered by supportive family behaviors in a sample of 192 adults with T2DM and low socioeconomic status using unadjusted and adjusted regression models. We found support for the exacerbating hypothesis. Stressors and nonadherence were only associated at higher levels of obstructive family behaviors (interaction AOR = 1.12, p = .002). Similarly, depressive symptoms and nonadherence were only associated at higher levels of obstructive family behaviors (interaction AOR = 3.31, p = .002). When participants reported few obstructive family behaviors, neither stressors nor depressive symptoms were associated with nonadherence. We did not find support for the buffering hypothesis; stressors and depressive symptoms were associated with nonadherence regardless of supportive family behaviors. Nonadherent patients experiencing stressors and/or major depressive symptoms may benefit from interventions that reduce obstructive family behaviors.

  7. Interaction between Maternal and Paternal SHMT1 C1420T Predisposes to Neural Tube Defects in the Fetus: Evidence from Case-Control and Family-Based Triad Approaches.

    Science.gov (United States)

    K Rebekah, Prasoona; Tella, Sunitha; Buragadda, Srinadh; Tiruvatturu, Muni Kumari; Akka, Jyothy

    2017-07-17

    Neural tube defects (NTDs) are caused by the failure of neural tube formation which occurs during early embryonic development. NTDs are the most severe and leading cause of fetal mortality. Serine hydroxymethyl transferase (SHMT1) provides one-carbon units necessary for embryogenesis and defects in one-carbon production result in specific pathological conditions during pregnancy. The present study is aimed to evaluate the association of SHMT1 C1420T with NTD risk in the fetus using fetal, maternal and paternal groups by applying both case-control and family-based triad approaches. A total of 924 subjects including 124 NTD case-parent trios (n = 124 × 3 = 372) and 184 healthy control-parent trios (n = 184 × 3 = 552) from Telangana State, South India were analyzed. DNA from umbilical cord tissues and parental blood samples were extracted, and genotyped by polymerase chain reaction-restriction fragment length polymorphism. Statistical analysis used were SPSS, parent-of-origin effect (POE) analysis. Case-control study design demonstrated fetuses with homozygous variant genotype (TT) to be at risk toward spina bifida subtype (p = 0.022). Among parents, fathers with TT genotype were associated with anencephaly (p = 0.018) and spina bifida subtypes (p = 0.027) in the offspring. Of interest, maternal-paternal-offspring genotype incompatibility revealed maternal CT genotype in combination with paternal TT genotype increased risk for NTDs in the fetus (CTxTT = TT; p = 0.021). Family-based parent-of-origin effect linkage analysis revealed significant maternal over-transmission of variant allele to NTD fetuses (p < 0.01). The present study, using both case-control and family-based triad approach is the first report to demonstrate parental association of SHMT1 C1420T variant in conferring NTD risk in the fetus. Birth Defects Research 109:1020-1029, 2017. © 2017 Wiley Periodicals, Inc. © 2017 Wiley Periodicals, Inc.

  8. An experimental study of the air-side particulate fouling in finned-tube heat exchangers of air conditioners through accelerated tests

    International Nuclear Information System (INIS)

    Ahn, Young Chull; Cho, Jae Min; Lee, Jae Keun; Lee, Hyun Uk; Ahn, Seung Phyo; Youn, Deok Hyun; Kang, Tae Wook; Ock, Ju Jo

    2003-01-01

    The air-side particulate fouling in the heat exchangers of HVAC applications degrades the performance of cooling capacity, pressure drop across a heat exchanger, and indoor air quality. Indoor and outdoor air contaminants foul heat exchangers. The purpose of this study is to investigate the fouling characteristics trough accelerated tests. The fouling characteristics are analyzed as functions of a dust concentration (1.28 and 3.84 g/m 3 ), a face velocity (0.5, 1.0, and 1.5 m/s), and a surface condition. The cooling capacity in the slitted finned-tube heat exchangers at the face velocity of 1 m/s decreases about 2% and the pressure drop increases up to 57%. The rate of build-up of fouling is observed to be 3 times slower for this three-fold reduction of dust concentration whilst still approaching the same asymptotic level

  9. Retrospective analysis of insulin responses to standard dosed oral glucose tests (OGTs) via naso-gastric tubing towards definition of an objective cut-off value.

    Science.gov (United States)

    Warnken, Tobias; Delarocque, Julien; Schumacher, Svenja; Huber, Korinna; Feige, Karsten

    2018-01-19

    Insulin dysregulation (ID) with basal or postprandial hyperinsulinemia is one of the key findings in horses and ponies suffering from the equine metabolic syndrome (EMS). Assessment of ID can easily be performed in clinical settings by the use of oral glucose challenge tests. Oral glucose test (OGT) performed with 1 g/kg bodyweight (BW) glucose administered via naso-gastric tube allows the exact administration of a defined glucose dosage in a short time. However, reliable cut-off values have not been available so far. Therefore, the aim of the study was to describe variations in insulin response to OGT via naso-gastric tubing and to provide a clinical useful cut-off value for ID when using the insulin quantification performed with an equine-optimized insulin enzyme-linked immunosorbent assay. Data visualization revealed no clear separation in the serum insulin concentration of insulin sensitive and insulin dysregulated horses during OGT. Therefore, a model based clustering method was used to circumvent the use of an arbitrary limit for categorization. This method considered all data-points for the classification, taking into account the individual insulin trajectory during the OGT. With this method two clusters were differentiated, one with low and one with high insulin responses during OGT. The cluster of individuals with low insulin response was consistently detected, independently of the initialization parameters of the algorithm. In this cluster the 97.5% quantile of insulin is 110 µLU/mL at 120 min. We suggest using this insulin concentration of 110 µLU/mL as a cut-off value for samples obtained at 120 min in OGT. OGT performed with 1 g/kg BW glucose and administration via naso-gastric tubing can easily be performed under clinical settings. Application of the cut-off value of 110 µLU/mL at 120 min allows assessment of ID in horses.

  10. Inspection tool for butt-welded tubing

    Science.gov (United States)

    Horman, D. P.

    1977-01-01

    Inspection tool for tubing consists of metal casing housing elastic collar. Collar is clamped around weld site under test. Leakage through weld is contained within chamber and is bled to detector via tubing attached to fitting. Tool, originally designed to detect fluid leakage in tubing, can be used to detect gas leaks.

  11. N Reactor pressure tube 1350 postirradiation examination

    International Nuclear Information System (INIS)

    Cook, D.J.

    1977-01-01

    The N Reactor pressure tubes were fabricated from Zircaloy-2 primarily due to the excellent corrosion resistance, low neutron absorption, and high strength properties of this alloy. Irradiation damage mechanisms increase the strength and decrease the ductility of the Zircaloy-2. Irradiation data available at the time the tubes were installed indicated that fast neutron irradiation damage mechanisms would not decrease the ductility to unacceptable levels over the estimated plant life of 25 to 30 years. However, because the tubes are a primary coolant system component and only limited data are available on irradiation effects at high fluences, a Postirradiation Examination (PIE) program was developed to assure that service factors do not compromise pressure tube integrity essential to reactor safety. The PIE program requires that a pressure tube be periodically removed from the reactor for destructive testing. The N Reactor Technical Specifications specify that the frequency of pressure tube removal and examination be based upon the previous PIE test results. Four pressure tubes were examined before tube 1350, and the test results were summarized in individual reports. PIE results on tube 1350 were summarized along with the test results on the previous four tubes in a previous report. The purpose of this report is to present in detail the results on PIE of pressure tube 1350, and, in particular, document the technique by which the fracture toughness of the pressure tube was determined

  12. The Family-Study Interface and Academic Outcomes: Testing a Structural Model

    Science.gov (United States)

    Meeuwisse, Marieke; Born, Marise Ph.; Severiens, Sabine E.

    2011-01-01

    Expanding on family-work and work-study models, this article investigated a model for family-study conflict and family-study facilitation. The focus of the study was the relationship of family-study conflict and family-study facilitation with students' effortful behaviors and academic performance among a sample of university students (N = 1,656).…

  13. photomultiplier tubes

    CERN Multimedia

    photomultiplier tubes. A device to convert light into an electric signal (the name is often abbreviated to PM). Photomultipliers are used in all detectors based on scintillating material (i.e. based on large numbers of fibres which produce scintillation light at the passage of a charged particle). A photomultiplier consists of 3 main parts: firstly, a photocathode where photons are converted into electrons by the photoelectric effect; secondly, a multiplier chain consisting of a serie of dynodes which multiply the number of electron; finally, an anode, which collects the resulting current.

  14. photomultiplier tube

    CERN Multimedia

    photomultiplier tubes. A device to convert light into an electric signal (the name is often abbreviated to PM). Photomultipliers are used in all detectors based on scintillating material (i.e. based on large numbers of fibres which produce scintillation light at the passage of a charged particle). A photomultiplier consists of 3 main parts: firstly, a photocathode where photons are converted into electrons by the photoelectric effect; secondly, a multiplier chain consisting of a serie of dynodes which multiply the number of electron; finally, an anode, which collects the resulting current.

  15. The biobehavioral family model: testing social support as an additional exogenous variable.

    Science.gov (United States)

    Woods, Sarah B; Priest, Jacob B; Roush, Tara

    2014-12-01

    This study tests the inclusion of social support as a distinct exogenous variable in the Biobehavioral Family Model (BBFM). The BBFM is a biopsychosocial approach to health that proposes that biobehavioral reactivity (anxiety and depression) mediates the relationship between family emotional climate and disease activity. Data for this study included married, English-speaking adult participants (n = 1,321; 55% female; M age = 45.2 years) from the National Comorbidity Survey Replication, a nationally representative epidemiological study of the frequency of mental disorders in the United States. Participants reported their demographics, marital functioning, social support from friends and relatives, anxiety and depression (biobehavioral reactivity), number of chronic health conditions, and number of prescription medications. Confirmatory factor analyses supported the items used in the measures of negative marital interactions, social support, and biobehavioral reactivity, as well as the use of negative marital interactions, friends' social support, and relatives' social support as distinct factors in the model. Structural equation modeling indicated a good fit of the data to the hypothesized model (χ(2)  = 846.04, p = .000, SRMR = .039, CFI = .924, TLI = .914, RMSEA = .043). Negative marital interactions predicted biobehavioral reactivity (β = .38, p social support, inversely (β = -.16, p social support as a predicting factor in the model. © 2014 Family Process Institute.

  16. Study of the performances of acoustic emission testing for glass fibre reinforced plastic pipes containing defects; Etude des performances du controle par emission acoustique de tubes en materiaux composites resine-fibre de verre contenant des defauts

    Energy Technology Data Exchange (ETDEWEB)

    Villard, D.; Vidal, M.C.

    1995-08-01

    Glass fibre reinforced plastic pipes are more and more often used, in nuclear power plants, for building or replacement of water pipings classified `nuclear safety`. Tests have been performed to evaluate the performances of acoustic emission testing for in service inspection of these components. The tests were focused on glass fibre reinforced polyester and vinyl-ester pipes, in as received conditions or containing impacts, and intentionally introduced defects. They have been carried out by CETIM, following the ASTM Standard E 1118 (code CARP), to a maximum pressure lever of 25 Bar The results show that the CARP procedure can be used for detection of defects and evaluation of their noxiousness towards internal pressure: most of the tubes containing low energy impacts could not be distinguished from tubes without defect; on the other hand the important noxiousness of lacks of impregnation of roving layer appeared clearly. Complementary tests have been performed on some tubes at a more important pressure lever, for which the damage of the tubes in enough to deteriorate there elastic properties. The results showed that CARP procedure give valuable informations on damage level. It would be interesting to evaluate acoustic emission on tubes containing realistic in-service degradations. (author). 11 refs., 15 figs., 6 tabs., 2 appends.

  17. Understanding Referral Patterns for Bone Mineral Density Testing among Family Physicians: A Qualitative Descriptive Study

    Directory of Open Access Journals (Sweden)

    Sarah E. P. Munce

    2016-01-01

    Full Text Available Introduction. Evidence of inappropriate bone mineral density (BMD testing has been identified in terms of overtesting in low risk women and undertesting among patients at high risk. In light of these phenomena, the objective of this study was to understand the referral patterns for BMD testing among Ontario’s family physicians (FPs. Methods. A qualitative descriptive approach was adopted. Twenty-two FPs took part in a semi-structured interview lasting approximately 30 minutes. An inductive thematic analysis was performed on the transcribed data in order to understand the referral patterns for BMD testing. Results. We identified a lack of clarity about screening for osteoporosis with a tendency for baseline BMD testing in healthy, postmenopausal women and a lack of clarity on the appropriate age for screening for men in particular. A lack of clarity on appropriate intervals for follow-up testing was also described. Conclusions. These findings lend support to what has been documented at the population level suggesting a tendency among FPs to refer menopausal women (at low risk. Emphasis on referral of high-risk groups as well as men and further clarification and education on the appropriate intervals for follow-up testing is warranted.

  18. Parental Socioeconomic Status, Communication, and Children's Vocabulary Development: A Third-Generation Test of the Family Investment Model

    Science.gov (United States)

    Sohr-Preston, Sara L.; Scaramella, Laura V.; Martin, Monica J.; Neppl, Tricia K.; Ontai, Lenna; Conger, Rand

    2013-01-01

    This third-generation, longitudinal study evaluated a family investment perspective on family socioeconomic status (SES), parental investments in children, and child development. The theoretical framework was tested for first-generation parents (G1), their children (G2), and the children of the second generation (G3). G1 SES was expected to…

  19. 40 CFR 1051.325 - What happens if an engine family fails the production-line testing requirements?

    Science.gov (United States)

    2010-07-01

    ... ENGINES AND VEHICLES Testing Production-Line Vehicles and Engines § 1051.325 What happens if an engine... for an engine family if it fails under § 1051.315. The suspension may apply to all facilities producing vehicles or engines from an engine family, even if you find noncompliant vehicles or engines only...

  20. Using a genetic test result in the care of family members: how does the duty of confidentiality apply?

    Science.gov (United States)

    Parker, Michael; Lucassen, Anneke

    2018-04-27

    The use of genetic and genomic testing is becoming more widespread in healthcare and more inherited explanations for family history of diseases or conditions are being uncovered. Currently, relevant genetic information is not always used in the care of family members who might benefit from it, because of health professionals' fears of inappropriately breaching another family member's confidence. Such examples are likely to increase as testing possibilities expand. Here we present the case for use of familial information in the care and treatment of family members. We argue that whilst a clinical diagnosis in person A is confidential, the discovery of a familial factor that led to this diagnosis should be available for use in depersonalised form by health professionals to inform the testing and clinical care of other family members. The possibility of such use should be made clear in clinical practice at the time of initial testing, but should not require consent from the person in whom the familial factor was first identified. We call for further debate on these questions in the wake of high profile non-disclosure of genetic information cases, and forthcoming Data Protection legislation changes.

  1. Experimental and calculation results of the integral reflood test QUENCH-14 with M5 (registered) cladding tubes

    International Nuclear Information System (INIS)

    Stuckert, J.; Birchley, J.; Grosse, M.; Jaeckel, B.; Steinbrueck, M.

    2010-01-01

    The QUENCH-14 experiment investigated the effect of M5 (registered) cladding material on bundle oxidation and core reflood, in comparison with tests QUENCH-06 (ISP-45) that used standard Zircaloy-4 and QUENCH-12 that used VVER E110-claddings. The PWR bundle configuration of QUENCH-14 with a single unheated rod, 20 heated rods, and four corner rods was otherwise identical to QUENCH-06. The test was conducted in principle with the same protocol as QUENCH-06, so that the effects of the change of cladding material could be observed more easily. Pre-test calculations were performed by the Paul Scherrer Institut (Switzerland) using the SCDAPSIM, SCDAP/RELAP5 and MELCOR codes. Follow-on post-test analyses were performed using SCDAP/RELAP5 and MELCOR as part of an ongoing programme of model validation and code assessment. Alternative oxidation correlations were used to examine the possible influence of the M5 (registered) cladding material on hydrogen generation, in comparison with Zircaloy-4. The experiment started with a pre-oxidation phase in steam, lasting ∼3000 s at ∼1500 K peak bundle temperature. After a further temperature increase to maximum bundle temperature of 2073 K the bundle was flooded with 2 g/s/rod water from the bottom. The peak temperature of ∼2300 K was measured on the bundle shroud, shortly after quench initiation. The electrical power was reduced to average value of 2 W/cm during the reflood phase to simulate effective decay heat level. Complete bundle cooling was reached in 300 s after reflood initiation. The development of the oxide layer growth during the test was essentially defined by measurements performed on the three Zircaloy-4 corner rods withdrawn successively from the bundle. The withdrawal of Zircaloy-4 and E110 corner rods after the test allowed a comparison of the different alloys in one test. One heated rod with M5 cladding was withdrawn after the test for a detailed analysis of oxidation degree and measurement of absorbed

  2. Data bank on hydrodynamics, thermal tests and tube temperature regimes of PGV-4 and PVG-1000 natural steam generators

    Energy Technology Data Exchange (ETDEWEB)

    Ageev, A.G.; Vasileva, R.V.; Nigmatulin, B.I.; Titov, V.F.; Tarankov, G.N. [EREC Electrogorsk Research and Engineering Centre of Nuclear Plants Safety, Moscow (Russian Federation)

    1995-12-31

    The data bank was prepared by EREC, OKB `Hydropress` using results of static and dynamic tests of PGV-4 and PGV- 1000 natural steam generators cared out at Kolskaya, Novo-Voronezhskaya, Ugno-Ukrainskaya, Balakov-skaya and Hmelnitskaya NPP within period of 1974-1993. It is destined for making calculation codes verification. (authors).

  3. Data bank on hydrodynamics, thermal tests and tube temperature regimes of PGV-4 and PVG-1000 natural steam generators

    Energy Technology Data Exchange (ETDEWEB)

    Ageev, A G; Vasileva, R V; Nigmatulin, B I; Titov, V F; Tarankov, G N [EREC Electrogorsk Research and Engineering Centre of Nuclear Plants Safety, Moscow (Russian Federation)

    1996-12-31

    The data bank was prepared by EREC, OKB `Hydropress` using results of static and dynamic tests of PGV-4 and PGV- 1000 natural steam generators cared out at Kolskaya, Novo-Voronezhskaya, Ugno-Ukrainskaya, Balakov-skaya and Hmelnitskaya NPP within period of 1974-1993. It is destined for making calculation codes verification. (authors).

  4. A classical Ehlers-Danlos syndrome family with incomplete presentation diagnosed by molecular testing.

    Science.gov (United States)

    Colombi, Marina; Dordoni, Chiara; Cinquina, Valeria; Venturini, Marina; Ritelli, Marco

    2018-01-01

    The 2017 EDS revised nosology indicates that minimal criteria suggestive for classical Ehlers-Danlos syndrome (cEDS) are skin hyperextensibility plus atrophic scarring together with either generalized joint hypermobility (gJHM) and/or at least three minor criteria that include cutaneous features and gJHM complications. Confirmatory molecular testing is obligatory to reach a final diagnosis. Although the large majority of the patients presents with these clinical features, some do not and might remain undiagnosed or misdiagnosed. Here we describe a family with 2 affected members, a 23-year-old proposita and her 51-year-old mother, who presented subtle cutaneous signs, including a variable degree of skin hyperextensibility without extensive widened atrophic scars that apparently better fitted with the overlapping hypermobile EDS. The proposita also presented gastrointestinal symptoms secondary to aberrant mast cells mediators release, making the clinical picture even more puzzling. Both patients were diagnosed by molecular testing that revealed a COL5A1 splice mutation. This report highlights the relevance of molecular analysis in patients presenting rather mild signs of EDS, especially in familial cases, and the importance of clinical expertise to make such a diagnosis. Copyright © 2017. Published by Elsevier Masson SAS.

  5. Impact of family language and testing language on reading performance in a bilingual educational context.

    Science.gov (United States)

    Elosua Oliden, Paula; Mujika Lizaso, Josu

    2014-01-01

    When different languages co-exist in one area, or when one person speaks more than one language, the impact of language on psychological and educational assessment processes can be considerable. The aim of this work was to study the impact of testing language in a community with two official languages: Spanish and Basque. By taking the PISA 2009 Reading Comprehension Test as a basis for analysis, four linguistic groups were defined according to the language spoken at home and the test language. Psychometric equivalence between test forms and differences in results among the four language groups were analyzed. The comparison of competence means took into account the effects of the index of socioeconomic and cultural status (ISEC) and gender. One reading unit with differential item functioning was detected. The reading competence means were considerably higher in the monolingual Spanish-Spanish group. No differences were found between the language groups based on family language when the test was conducted in Basque. The study illustrates the importance of taking into account psychometric, linguistic and sociolinguistic factors in linguistically diverse assessment contexts.

  6. Verification tests for GRAD, a computer program to predict nonuniform deformation and failure of Zr-2.5 wt percent Nb pressure tubes during a postulated loss-of-coolant accident

    International Nuclear Information System (INIS)

    Shewfelt, R.S.W.; Godin, D.P.

    1985-03-01

    During a postulated loss-of-coolant accident in a CANDU reactor, the temperature of the pressure tubes could rise sufficiently so that ballooning could occur. It is also likely that there would be a variation in temperature around the tube circumference, causing the deformation to be nonuniform. Since the deformation of the pressure tube controls how the core heat is transferred to the surrounding moderator, which is a large heat sink, a computer program, GRAD, has been developed to predict this nonuniform deformation. Numerous biaxial creep tests were done, where the temperature of internally pressurized sections of Zr-2.5 wt percent Nb pressure tubes were ramped to check the ability of GRAD to predict the resulting nonuniform deformation and possible tube failure. GRAD was successful in predicting the average transverse creep strain observed during the tests and the local transverse creep strain at the end of the tests. GRAD was also able to predict the failure time and average transverse creep strain at failure for all the specimens that failed

  7. Evaluation of the Widal tube agglutination test for the diagnosis of typhoid fever among children admitted to a rural hdospital in Tanzania and a comparison with previous studies

    Directory of Open Access Journals (Sweden)

    Malahiyo Rajabu

    2010-06-01

    Full Text Available Abstract Background The diagnosis of typhoid fever is confirmed by culture of Salmonella enterica serotype Typhi (S. typhi. However, a more rapid, simpler, and cheaper diagnostic method would be very useful especially in developing countries. The Widal test is widely used in Africa but little information exists about its reliability. Methods We assessed the performance of the Widal tube agglutination test among febrile hospitalized Tanzanian children. We calculated the sensitivity, specificity, positive predictive value (PPV, and negative predictive value (NPV of various anti-TH and -TO titers using culture-confirmed typhoid fever cases as the "true positives" and all other febrile children with blood culture negative for S. typhi as the "true negatives." Results We found that 16 (1% of 1,680 children had culture-proven typhoid fever. A single anti-TH titer of 1:80 and higher was the optimal indicator of typhoid fever. This had a sensitivity of 75%, specificity of 98%, NPV of 100%, but PPV was only 26%. We compared our main findings with those from previous studies. Conclusion Among febrile hospitalized Tanzanian children with a low prevalence of typhoid fever, a Widal titer of ≥ 1:80 performed well in terms of sensitivity, specificity, and NPV. However a test with improved PPV that is similarly easy to apply and cost-efficient is desirable.

  8. Measurement of impulse peak insertion loss from two acoustic test fixtures and four hearing protector conditions with an acoustic shock tube

    Science.gov (United States)

    Murphy, William J.; Fackler, Cameron J.; Berger, Elliott H.; Shaw, Peter B.; Stergar, Mike

    2015-01-01

    Impulse peak insertion loss (IPIL) was studied with two acoustic test fixtures and four hearing protector conditions at the E-A-RCAL Laboratory. IPIL is the difference between the maximum estimated pressure for the open-ear condition and the maximum pressure measured when a hearing protector is placed on an acoustic test fixture (ATF). Two models of an ATF manufactured by the French-German Research Institute of Saint-Louis (ISL) were evaluated with high-level acoustic impulses created by an acoustic shock tube at levels of 134 decibels (dB), 150 dB, and 168 dB. The fixtures were identical except that the E-A-RCAL ISL fixture had ear canals that were 3 mm longer than the National Institute for Occupational Safety and Health (NIOSH) ISL fixture. Four hearing protection conditions were tested: Combat Arms earplug with the valve open, ETYPlugs® earplug, TacticalPro headset, and a dual-protector ETYPlugs earplug with TacticalPro earmuff. The IPILs measured for the E-A-RCAL fixture were 1.4 dB greater than the National Institute for Occupational Safety and Health (NIOSH) ISL ATF. For the E-A-RCAL ISL ATF, the left ear IPIL was 2.0 dB greater than the right ear IPIL. For the NIOSH ATF, the right ear IPIL was 0.3 dB greater than the left ear IPIL. PMID:26356380

  9. Comparison of Rose Bengal Plate Agglutination, Standard tube agglutination and Indirect ELISA tests for detection of Brucella antibodies in Cows and Buffaloes

    Directory of Open Access Journals (Sweden)

    S. N. Ghodasara

    2010-04-01

    Full Text Available A total of 180 serum samples (107 cows, 73 buffaloes from cases of abortion and various reproductive disorders were collected for detection of Brucella antibody by Rose Bengal Plate Agglutination Test (RBPT, Serum Tube Agglutination Test (STAT and indirect- ELISA (i-ELISA. The overall prevalence of brucellosis by RBPT, STAT and i-ELISA were 11.21%, 16.00% and 24.30% in cows 9.59%, 12.33% and 26.03% in buffaloes respectively. Overall seroprevalence of Brucellosis in cases of abortion, R.O.P. by RBPT, STAT and i-ELISA were 11.32%, 16.04% and 32.08% respectively. When three serological tests were compared, seropositivity was found highest by i-ELISA (25%, followed by STAT (14.45% and RBPT (10.56%. The results shows higher prevalence of brucellosis in cases of abortion and R.O.P., while at lower level from various reproductive disorders as detected serologically indicating endemicity of the infection in villages around Anand city, Gujarat. [Vet. World 2010; 3(2.000: 61-64

  10. Neutron image intensifier tubes

    International Nuclear Information System (INIS)

    Verat, M.; Rougeot, H.; Driard, B.

    1983-01-01

    The most frequently used techniques in neutron radiography employ a neutron converter consisting of either a scintillator or a thin metal sheet. The radiation created by the neutrons exposes a photographic film that is in contact with the converter: in the direct method, the film is exposed during the time that the object is irradiated with neutrons; in the transfer method, the film is exposed after the irradiation of the object with neutrons. In industrial non-destructive testing, when many identical objects have to be checked, these techniques have several disadvantages. Non-destructive testing systems without these disadvantages can be constructed around neutron-image intensifier tubes. A description and the operating characteristics of neutron-image intensifier tubes are given. (Auth.)

  11. Boiling heat transfer on horizontal tube bundles

    International Nuclear Information System (INIS)

    Anon.

    1987-01-01

    Nucleate boiling heat transfer characteristics for a tube in a bundle differ from that for a single tube in a pool and this difference is known as 'tube bundle effect.' There exist two bundle effects, positive and negative. The positive bundle effect enhances heat transfer due to convective flow induced by rising bubbles generated from the lower tubes, while the negative bundle effect deteriorates heat transfer due to vapor blanketing caused by accumulation of bubbles. Staggered tube bundles tested and found that the upper tubes in bundles have higher heat transfer coefficients than the lower tubes. The effects of various parameters such as pressure, tube geometry and oil contamination on heat transfer have been examined. Some workers attempted to clarify the mechanism of occurrence of 'bundle effect' by testing tube arrangements of small scale. All reported only enhancement in heat transfer but results showed the symptom of heat transfer deterioration at higher heat fluxes. As mentioned above, it has not been clarified so far even whether the 'tube bundle effect' should serve as enhancement or deterioration of heat transfer in nucleate boiling. In this study, experiments are performed in detail by using bundles of small scale, and effects of heat flux distribution, pressure and tube location are clarified. Furthermore, some consideration on the mechanisms of occurrence of 'tube bundle effect' is made and a method for prediction of heat transfer rate is proposed

  12. Improving the calandria tubes for CANDU reactors

    International Nuclear Information System (INIS)

    Coleman, C.E.; Fong, R.W.L.; Doubt, G.L.

    1997-01-01

    CANDU calandria tubes are made from annealed Zircaloy-2 sheet formed into a cylinder and welded along its length to make the tube. The current calandria tubes have given exemplary service for many years. With more stringent regulations and the need to accommodate warm cooling water in tropical countries, we started a development program to increase the margins for failure during postulated accidents. These improvements involve increasing the tube strength and optimising the heat-transfer from an excessively hot fuel channel to the cool moderator. If the postulated accident involves a pressure tube break, it would be desirable if the calandria tube withstood the full pressure of the heat-transport system. The weakest link in current calandria tubes is the weld. Thickening the weld can increase the strength by 20% while seamless tubes can be 45% stronger than current tubes. The latter tubes can hold full system pressure for many hours without failure. If during the postulated accident the fuel and pressure tube become excessively hot but do not touch the calandria tube, the radiant heat loss must be maximised. Current calandria tubes have an absorptivity (emissivity) of about 0.2. To protect the fuel and the fuel channel we have devised a finish to the inside surface of the calandria tube that increases the emissivity to 0.7. If during the postulated accident the hot pressure tube touches the cool calandria tube, the contact conductance and the critical heat flux must be optimised to ensure nucleate boiling of the moderator at the outside surface of the calandria tube and therefore efficient exploitation of the moderator as a heat sink. In laboratory tests small ridges on the inside surface and roughening of the outside surface have been shown to increase the margins against failure and increase the possible moderator temperatures thus providing the opportunity to decrease the cost of the moderator heat-exchange system and remove restrictions on reactor operation in

  13. AFNOR validation of Premi Test, a microbiological-based screening tube-test for the detection of antimicrobial residues in animal muscle tissue.

    Science.gov (United States)

    Gaudin, Valerie; Juhel-Gaugain, Murielle; Morétain, Jean-Pierre; Sanders, Pascal

    2008-12-01

    Premi Test contains viable spores of a strain of Bacillus stearothermophilus which is sensitive to antimicrobial residues, such as beta-lactams, tetracyclines, macrolides and sulphonamides. The growth of the strain is inhibited by the presence of antimicrobial residues in muscle tissue samples. Premi Test was validated according to AFNOR rules (French Association for Normalisation). The AFNOR validation was based on the comparison of reference methods (French Official method, i.e. four plate test (FPT) and the STAR protocol (five plate test)) with the alternative method (Premi Test). A preliminary study was conducted in an expert laboratory (Community Reference Laboratory, CRL) on both spiked and incurred samples (field samples). Several method performance criteria (sensitivity, specificity, relative accuracy) were estimated and are discussed, in addition to detection capabilities. Adequate agreement was found between the alternative method and the reference methods. However, Premi Test was more sensitive to beta-lactams and sulphonamides than the FPT. Subsequently, a collaborative study with 11 laboratories was organised by the CRL. Blank and spiked meat juice samples were sent to participants. The expert laboratory (CRL) statistically analysed the results. It was concluded that Premi Test could be used for the routine determination of antimicrobial residues in muscle of different animal origin with acceptable analytical performance. The detection capabilities of Premi Test for beta-lactams (amoxicillin, ceftiofur), one macrolide (tylosin) and tetracycline were at the level of the respective maximum residue limits (MRL) in muscle samples or even lower.

  14. Slit-burst testing of cold-worked Zr-2.5 wt.% Nb pressure tubing for CANDU-PHW reactors

    International Nuclear Information System (INIS)

    Wilkins, B.J.S.; Barrie, J.N.; Zink, R.J.

    1978-12-01

    This report documents the available data on critical crack length of cold-worked Zr-2.5 wt.% Nb pressure tubing in CANDU reactors. In particular, it includes data for tubing removed from the Pickering 3 and 4 reactors. (author)

  15. Design and testing of a magnetic shield for the Thomson scattering photomultiplier tubes in the stray fields of the ERASMUS tokamak

    International Nuclear Information System (INIS)

    Desoppere, E.; Van Oost, G.

    1983-01-01

    A multiple coaxial shield system has been designed for the photomultiplier tubes of the ERASMUS tokamak Thomson scattering diagnostic. A stray field of 75 x 10 -4 T was reduced to 0.01 x 10 -4 T for a field parallel to the tube axis, and to 0.03 x 10 -4 T for a perpendicular field

  16. Validity and power of association testing in family-based sampling designs: evidence for and against the common wisdom.

    Science.gov (United States)

    Knight, Stacey; Camp, Nicola J

    2011-04-01

    Current common wisdom posits that association analyses using family-based designs have inflated type 1 error rates (if relationships are ignored) and independent controls are more powerful than familial controls. We explore these suppositions. We show theoretically that family-based designs can have deflated type-error rates. Through simulation, we examine the validity and power of family designs for several scenarios: cases from randomly or selectively ascertained pedigrees; and familial or independent controls. Family structures considered are as follows: sibships, nuclear families, moderate-sized and extended pedigrees. Three methods were considered with the χ(2) test for trend: variance correction (VC), weighted (weights assigned to account for genetic similarity), and naïve (ignoring relatedness) as well as the Modified Quasi-likelihood Score (MQLS) test. Selectively ascertained pedigrees had similar levels of disease enrichment; random ascertainment had no such restriction. Data for 1,000 cases and 1,000 controls were created under the null and alternate models. The VC and MQLS methods were always valid. The naïve method was anti-conservative if independent controls were used and valid or conservative in designs with familial controls. The weighted association method was generally valid for independent controls, and was conservative for familial controls. With regard to power, independent controls were more powerful for small-to-moderate selectively ascertained pedigrees, but familial and independent controls were equivalent in the extended pedigrees and familial controls were consistently more powerful for all randomly ascertained pedigrees. These results suggest a more complex situation than previously assumed, which has important implications for study design and analysis. © 2011 Wiley-Liss, Inc.

  17. Effect of tube-support interaction on the dynamic responses of heat exchanger tubes

    International Nuclear Information System (INIS)

    Shin, Y.S.; Jendrzejczyk, J.A.; Wambsganss, M.W.

    1977-01-01

    Operating heat exchangers have experienced tube damages due to excessive flow-induced vibration. The relatively small inherent tube-to-baffle hole clearances associated with manufacturing tolerances in heat exchangers affect the tube vibrational characteristics. In attempting a theoretical analysis, questions arise as to the effects of tube-baffle impacting on dynamic responses. Experiments were performed to determine the effects of tube-baffle impacting in vertical/horizontal tube orientation, and in air/water medium on the vibrational characteristics (resonant frequencies, mode shapes, and damping) and displacement response amplitudes of a seven-span tube model. The tube and support conditions were prototypic, and overall length approximately one-third that of a straight tube segment of the steam generator designed for the CRBR. The test results were compared with the analytical results based on the multispan beam with ''knife-edge'' supports

  18. Procedure and device for extracting the end of a tube inserted into a hole in a tube plate

    International Nuclear Information System (INIS)

    1980-01-01

    When constructing heat exchangers and steam generators, particularly in the construction of steam generators for nuclear power stations, many small diameter tubes have to be secured into a very thick tube plate for instance 600 mm thick. This crimping or expanding of the tube is generally performed by rolling the internal surface of the tube inside a hole drilled right through the tube plate and slightly greater in diameter than the external diameter of the tube before the tube is rolled. To check the tubes for defects, it is necessary to extract certain tubes from the tube plate in order to move the tube to a testing and inspection point and examine the part of it that was secured in the plate hole. The invention concerns the uncrimping of these tubes [fr

  19. Eustachian tube patency

    Science.gov (United States)

    Eustachian tube patency refers to how much the eustachian tube is open. The eustachian tube runs between the middle ear and the throat. It controls the pressure behind the eardrum and middle ear space. This helps keep ...

  20. Feeding tube - infants

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/article/007235.htm Feeding tube - infants To use the sharing features on this page, please enable JavaScript. A feeding tube is a small, soft, plastic tube placed ...

  1. Ethical issues in the use of genetic testing of patients with schizophrenia and their families.

    Science.gov (United States)

    DeLisi, Lynn E

    2014-05-01

    This review outlines the positive and negative aspects of DNA testing and provides an account of the issues particularly relevant to schizophrenia. Modern technology has changed the field of medicine so rapidly that patients and their families have become much more independent in their healthcare decisions than in the previous decade. Simply by finding information on the Internet, they gain knowledge about disease diagnosis, treatment options and their side-effects. No medical field likely has been more affected and more controversial than that of genetics. It is now possible to sequence the individual human genome and detect single nucleotide variations, microdeletions and duplications within it. Commercial companies have sprung up in a similar manner to the software or electronic industries and have begun to market direct-to-consumer DNA testing. Much of this may be performed to satisfy curiosity about one's ancestry; but commercially available results that appear incidentally can also be distributed to the consumer. Ethicists, genetics researchers, clinicians and government agencies are currently in discussion about concerns raised about commercially available DNA testing, while at the same time recognizing its value in some instances to be able to predict very serious disabilities.

  2. A multicenter family practitioners' research on Chronic Obstructive Pulmonary Disease screening using the COPD Assessment Test.

    Science.gov (United States)

    Demirci, Hakan; Eniste, Koncuy; Basaran, Ebru Onuker; Ocakoglu, Gokhan; Yilmaz, Zeynep; Tuna, Sumeyye

    2017-11-01

    Spirometry is known to be a gold standard for the diagnosis of chronic obstructive pulmonary disease (COPD). COPD Assessment Test (CAT) is an eight-item questionnaire currently in use to evaluate patients with COPD. In the present study, we aimed to evaluate if CAT is an adequate tool for screening COPD. In total, 600 persons aging ⩾40 years old were randomly selected from three different family practice units located in the city center. CAT was asked to the participants and a spirometry was used to assess pulmonary obstruction. Pulmonary obstruction was defined as forced expiratory volume in first second/forced vital capacity (FEV1/FVC)COPD diagnosis was confirmed with the reversibility test. The relationship between CAT results and pulmonary function test values was evaluated. In this sampling, the prevalence of COPD was 4.2%. Reliability of the CAT in the study group was acceptable (Cronbach's α: 0.84). The CAT scores was significantly higher in patients with COPD (PCOPD. CAT is a reliable questionnaire and there is an apparent relationship between the total CAT scores and COPD. However, CAT's ability to screen COPD is limited since it may miss the symptom-free cases.

  3. Gasification in a revolving tube

    International Nuclear Information System (INIS)

    Speicher, R.F.

    1981-01-01

    The concept of a method for allothermal coal gasification is to refine raw lignite from the Rhine area to high-quality synthesis gas or reduction gas without extracting the water utilizing nuclear process heat in a heated revolving bundle of tubes. Computational models are described for the macroscopic course of events in parallel flow gasification. In the design of the test plant, the principle of drag-in and transport of the tube drier was applied. (DG) [de

  4. Parent-child genetic testing for familial hypercholesterolaemia in an Australian context.

    Science.gov (United States)

    Pang, Jing; Martin, Andrew C; Bates, Timothy R; Hooper, Amanda J; Bell, Damon A; Burnett, John R; Norman, Richard; Watts, Gerald F

    2018-04-06

    The aim of this study was to evaluate the clinical outcome of parent-child testing for familial hypercholesterolaemia (FH) employing genetic testing and the likely additional cost of treating each child. Parent-child testing for gene variants causative of FH was carried out according to Australian guidelines. The number of new cases detected, the low-density lipoprotein (LDL)-cholesterol that best predicted a mutation and the proportional reduction in LDL-cholesterol following statin treatment was evaluated. Treatment costs were calculated as the cost per mmol/L reduction in LDL-cholesterol. A total of 126 adult patients, known to have a pathogenic mutation causative of FH, and their children were studied. From 244 children identified, 148 (60.7%) were genetically screened; 84 children were identified as mutative positive (M+) and 64 as mutative negative. Six of the M+ children were already on statin treatment; 40 were subsequently treated with low-dose statins, with LDL-cholesterol falling significantly by 38% (P < 0.001). The estimated cost per mmol/L reduction of LDL-cholesterol of a child receiving statins from ages 10 to 18 years is AU$1361, which can potentially be cost-effective. An LDL-cholesterol threshold of 3.5 mmol/L had a sensitivity of 92.8% and specificity of 96.6% for the detection of a mutation. Genetic testing of children of affected parents with FH is an effective means of detecting new cases of FH. Cascade testing can enable early statin therapy with significant reductions in LDL-cholesterol concentration. © 2018 Paediatrics and Child Health Division (The Royal Australasian College of Physicians).

  5. Performance test results of helium gas circulator of mock-up test facility with full-scale reaction tube for HTTR hydrogen production system. Contract research

    Energy Technology Data Exchange (ETDEWEB)

    Shimizu, Akira; Kato, Michio; Hayashi, Koji [Japan Atomic Energy Research Inst., Oarai, Ibaraki (Japan). Oarai Research Establishment] [and others

    2003-03-01

    Hydrogen production system by steam reforming of methane will be connected to the High Temperature Engineering Test Reactor (HTTR) of the Japan Atomic Energy Research Institute (JAERI) against development of nuclear heat utilization system. To obtain design and safety database of the HTTR hydrogen production system, mock-up test facility with full-scale reaction was constructed in FY 2001 and hydrogen of 120m{sup 3}N{sub /}h was successfully produced in overall performance test. This report describes performance test results of a helium gas circulator in this facility. The circulator performance curves regarding to pressure-rise, input power and adiabatic thermal efficiency at standard revolution number were made based on the measured flow-rate, temperature and pressure data in overall performance test. The circulator performance prediction code was made based on these performance curves. The code can calculate revolution number, electric power and temperature-rise of the circulator using flow-rate, inlet temperature, inlet pressure and pressure-rise data. The verification of the code was carried out with the test data in FY 2002. Total pressure loss of the helium gas circulation loop was also evaluated. The circulator should be operated in conditions such as pressure from 2.7MPa to 4.0MPa and flow-rate from 250g/s to 400g/s and at maximum pressure-rise of 250 kPa in test operation. It was confirmed in above verification and evaluations that the circulator had performance to satisfy above conditions within operation limitation of the circulator such as maximum input-power of 150 kW and maximum revolution number of 12,000 rpm. (author)

  6. Interventions to Increase Male Attendance and Testing for Sexually Transmitted Infections at Publicly-Funded Family Planning Clinics.

    Science.gov (United States)

    Fine, David; Warner, Lee; Salomon, Sarah; Johnson, David M

    2017-07-01

    We assessed the impact of staff, clinic, and community interventions on male and female family planning client visit volume and sexually transmitted infection testing at a multisite community-based health care agency. Staff training, clinic environmental changes, in-reach/outreach, and efficiency assessments were implemented in two Family Health Center (San Diego, CA) family planning clinics during 2010-2012; five Family Health Center family planning programs were identified as comparison clinics. Client visit records were compared between preintervention (2007-2009) and postintervention (2010-2012) for both sets of clinics. Of 7,826 male client visits during the time before intervention, most were for clients who were aged male visits (4,004 to 8,385; Δ = +109%); for comparison clinics, male visits increased modestly (3,822 to 4,500; Δ = +18%). The proportion of male clinic visits where chlamydia testing was performed increased in intervention clinics (35% to 42%; p males yielded similar findings for male client volume and chlamydia testing. The number of female visits declined nearly 40% in both comparison (21,800 to 13,202; -39%) and intervention clinics (30,830 to 19,971; -35%) between preintervention and postintervention periods. Multilevel interventions designed to increase male client volume and sexually transmitted infection testing services in family planning clinics succeeded without affecting female client volume or services. Copyright © 2017 Society for Adolescent Health and Medicine. All rights reserved.

  7. Tube holding system

    International Nuclear Information System (INIS)

    Cunningham, R.C.

    1978-01-01

    A tube holding rig is described for the lateral support of tubes arranged in tight parcels in a heat exchanger. This tube holding rig includes not less than two tube supporting assemblies, with a space between them, located crosswise with respect to the tubes, each supporting assembly comprising a first set of parallel components in contact with the tubes, whilst a second set of components is also in contact with the tubes. These two sets of parts together define apertures through which the tubes pass [fr

  8. HV Switch Tube Development Program status report: April 28, 1978

    International Nuclear Information System (INIS)

    Winje, R.A.

    1978-01-01

    The HV Switch Tube Development Program encompassed development contracts to both Eimac (Division of Varian) and RCA. Both companies were required to develop a design for the tube and to build and test two tubes. The development program began in April, 1976. Currently, both companies have built tubes; Eimac has built one and RCA has built two. As initially built, both tubes exhibited unstable operation; however, RCA has implemented design changes which stabilized the tube operation. Eimac has a design modification which they believe will produce stable operation when the change is implemented. Both tubes have been tested to a limited degree and no other abnormal characteristics have been observed

  9. A new powerful non-parametric two-stage approach for testing multiple phenotypes in family-based association studies

    NARCIS (Netherlands)

    Lange, C; Lyon, H; DeMeo, D; Raby, B; Silverman, EK; Weiss, ST

    2003-01-01

    We introduce a new powerful nonparametric testing strategy for family-based association studies in which multiple quantitative traits are recorded and the phenotype with the strongest genetic component is not known prior to the analysis. In the first stage, using a population-based test based on the

  10. Family-site interaction in Pinus radiata: implications for progeny testing strategy and regionalised breeding in New Zealand.

    Science.gov (United States)

    G.R. Johnson; R.D. Brudon

    1990-01-01

    A progeny test of 170 open-pollinated families from second-generation plus trees of Pinus radiata was established on four sites in New Zealand in 1981. Two test sites were on volcanic purnice soils in the Central North Island region and two were on phosphate-retentive clay soils in the Northland region.Assessments of volume growth, stem straightness, mal-...

  11. External quality assessment in the voluntary counseling and testing centers in the Brazilian Amazon using dried tube specimens: results of an effectiveness evaluation

    Directory of Open Access Journals (Sweden)

    Andréa Mônica Brandão Beber

    2015-06-01

    Full Text Available INTRODUCTION : In 2011, the Brazilian Ministry of Health rolled out a program for the external quality assessment of rapid human immunodeficiency virus (HIV tests using the dried tube specimen (DTS method (EQA-RT/DTS-HIV. Our objective was to evaluate the implementation of this program at 71 voluntary counseling and testing centers (VCTCs in the Brazilian Legal Amazonian area one year after its introduction. METHODS : Quantitative and qualitative study that analyzed secondary data and interviews with healthcare workers (HCWs (n=39 and VCTC coordinators (n=32 were performed. The assessment used 18 key indicators to evaluate the three dimensions of the program's logical framework: structure, process, and result. Each indicator was scored from 1-4, and the aggregate results corresponding to the dimensions were expressed as proportions. The results were compared to the perceptions of the HCWs and coordinators regarding the EQA-RT/DTS-HIV program. RESULTS: The aggregate scores for the three dimensions of structure, process, and result were 91.7%, 78.6%, and 95%, respectively. The lowest score in each dimension corresponded to a different indicator: access to Quali-TR online system 39% (structure, registration in Quali-TR online system 38.7% (process, and VCTC completed the full process in the program's first round 63.4% (result. Approximately 36% of the HCWs and 52% of the coordinators reported enhanced trust in the program for its rapid HIV testing performance. CONCLUSIONS: All three program dimensions exhibited satisfactory results (>75%. Nevertheless, the study findings highlight the need to improve certain program components. Additionally, long-term follow-ups is needed to provide a more thorough picture of the process for external quality assessment.

  12. Testing the quantity–quality model of fertility: Estimation using unrestricted family size models

    OpenAIRE

    Mogstad, Magne; Wiswall, Matthew

    2016-01-01

    We examine the relationship between child quantity and quality. Motivated by the theoretical ambiguity regarding the sign of the marginal effects of additional siblings on children's outcomes, our empirical model allows for an unrestricted relationship between family size and child outcomes. We find that the conclusion in Black, Devereux, and Salvanes (2005) of no family size effect does not hold after relaxing their linear specification in family size. We find nonzero effects of family size ...

  13. Thermomechanical Model and Bursting Tests to Evaluate the Risk of Swelling and Bursting of Modified 9Cr-1Mo Steel Steam Generator Tubes during a Sodium-Water Reaction Accident

    Directory of Open Access Journals (Sweden)

    C. Bertrand

    2014-01-01

    Full Text Available The MECTUB code was developed to evaluate the risk of swelling and bursting of Steam Generator (SG tubes. This code deals with the physic of intermediate steam-water leaks into sodium which induce a Sodium-Water Reaction (SWR. It is based on a one-dimensional calculation to describe the thermomechanical behavior of tubes under a high internal pressure and a fast external overheating. The mechanical model of MECTUB is strongly correlated with the kind of the material of the SG tubes. It has been developed and validated by using experiments performed on the alloy 800. A change to tubes made of Modified 9Cr-1Mo steel requires more knowledge of Modified 9Cr-1Mo steel behavior which influences the bursting time at high temperatures (up to 1200°C. Studies have been initiated to adapt the mechanical model and to qualify it for this material. The first part of this paper focuses on the mechanical law modelling (elasticity, plasticity, and creep for Modified 9Cr-1Mo steel and on overheating thermal data. In a second part, the results of bursting tests performed on Modified 9Cr-1Mo tubes in the SQUAT facility of CEA are used to validate the mechanical model of MECTUB for the Modified 9Cr-1Mo material.

  14. Social media for message testing: a multilevel approach to linking favorable viewer responses with message, producer, and viewer influence on YouTube.

    Science.gov (United States)

    Paek, Hye-Jin; Hove, Thomas; Jeon, Jehoon

    2013-01-01

    To explore the feasibility of social media for message testing, this study connects favorable viewer responses to antismoking videos on YouTube with the videos' message characteristics (message sensation value [MSV] and appeals), producer types, and viewer influences (viewer rating and number of viewers). Through multilevel modeling, a content analysis of 7,561 viewer comments on antismoking videos is linked with a content analysis of 87 antismoking videos. Based on a cognitive response approach, viewer comments are classified and coded as message-oriented thought, video feature-relevant thought, and audience-generated thought. The three mixed logit models indicate that videos with a greater number of viewers consistently increased the odds of favorable viewer responses, while those presenting humor appeals decreased the odds of favorable message-oriented and audience-generated thoughts. Some significant interaction effects show that videos produced by laypeople may hinder favorable viewer responses, while a greater number of viewer comments can work jointly with videos presenting threat appeals to predict favorable viewer responses. Also, for a more accurate understanding of audience responses to the messages, nuance cues should be considered together with message features and viewer influences.

  15. Parental feeding practices in Mexican American families: initial test of an expanded measure

    Science.gov (United States)

    2013-01-01

    Background Although obesity rates are high among Latino children, relatively few studies of parental feeding practices have examined Latino families as a separate group. Culturally-based approaches to measurement development can begin to identify parental feeding practices in specific cultural groups. This study used qualitative and quantitative methods to develop and test the Parental Feeding Practices (PFP) Questionnaire for use with Mexican American parents. Items reflected both parent’s use of control over child eating and child-centered feeding practices. Methods In the qualitative phase of the research, 35 Latino parents participated in focus groups. Items for the PFP were developed from focus group discussions, as well as adapted from existing parent feeding practice measures. Cognitive interviews were conducted with 37 adults to evaluate items. In the quantitative phase, mothers and fathers of 174 Mexican American children ages 8–10 completed the PFP and provided demographic information. Anthropometric measures were obtained on family members. Results Confirmatory factor analyses identified four parental feeding practice dimensions: positive involvement in child eating, pressure to eat, use of food to control behavior, and restriction of amount of food. Factorial invariance modeling suggested equivalent factor meaning and item response scaling across mothers and fathers. Mothers and fathers differed somewhat in their use of feeding practices. All four feeding practices were related to child body mass index (BMI) percentiles, for one or both parents. Mothers reporting more positive involvement had children with lower BMI percentiles. Parents using more pressure to eat had children with lower BMI percentiles, while parents using more restriction had children with higher BMI percentiles. Fathers using food to control behavior had children with lower BMI percentiles. Conclusions Results indicate good initial validity and reliability for the PFP. It can be

  16. Home medication support for childhood cancer: family-centered design and testing.

    Science.gov (United States)

    Walsh, Kathleen E; Biggins, Colleen; Blasko, Deb; Christiansen, Steven M; Fischer, Shira H; Keuker, Christopher; Klugman, Robert; Mazor, Kathleen M

    2014-11-01

    Errors in the use of medications at home by children with cancer are common, and interventions to support correct use are needed. We sought to (1) engage stakeholders in the design and development of an intervention to prevent errors in home medication use, and (2) evaluate the acceptability and usefulness of the intervention. We convened a multidisciplinary team of parents, clinicians, technology experts, and researchers to develop an intervention using a two-step user-centered design process. First, parents and oncologists provided input on the design. Second, a parent panel and two oncology nurses refined draft materials. In a feasibility study, we used questionnaires to assess usefulness and acceptability. Medication error rates were assessed via monthly telephone interviews with parents. We successfully partnered with parents, clinicians, and IT experts to develop Home Medication Support (HoMeS), a family-centered Web-based intervention. HoMeS includes a medication calendar with decision support, a communication tool, adverse effect information, a metric conversion chart, and other information. The 15 families in the feasibility study gave HoMeS high ratings for acceptability and usefulness. Half recorded information on the calendar to indicate to other caregivers that doses were given; 34% brought it to the clinic to communicate with their clinician about home medication use. There was no change in the rate of medication errors in this feasibility study. We created and tested a stakeholder-designed, Web-based intervention to support home chemotherapy use, which parents rated highly. This tool may prevent serious medication errors in a larger study. Copyright © 2014 by American Society of Clinical Oncology.

  17. Parental feeding practices in Mexican American families: initial test of an expanded measure

    Directory of Open Access Journals (Sweden)

    Tschann Jeanne M

    2013-01-01

    Full Text Available Abstract Background Although obesity rates are high among Latino children, relatively few studies of parental feeding practices have examined Latino families as a separate group. Culturally-based approaches to measurement development can begin to identify parental feeding practices in specific cultural groups. This study used qualitative and quantitative methods to develop and test the Parental Feeding Practices (PFP Questionnaire for use with Mexican American parents. Items reflected both parent’s use of control over child eating and child-centered feeding practices. Methods In the qualitative phase of the research, 35 Latino parents participated in focus groups. Items for the PFP were developed from focus group discussions, as well as adapted from existing parent feeding practice measures. Cognitive interviews were conducted with 37 adults to evaluate items. In the quantitative phase, mothers and fathers of 174 Mexican American children ages 8–10 completed the PFP and provided demographic information. Anthropometric measures were obtained on family members. Results Confirmatory factor analyses identified four parental feeding practice dimensions: positive involvement in child eating, pressure to eat, use of food to control behavior, and restriction of amount of food. Factorial invariance modeling suggested equivalent factor meaning and item response scaling across mothers and fathers. Mothers and fathers differed somewhat in their use of feeding practices. All four feeding practices were related to child body mass index (BMI percentiles, for one or both parents. Mothers reporting more positive involvement had children with lower BMI percentiles. Parents using more pressure to eat had children with lower BMI percentiles, while parents using more restriction had children with higher BMI percentiles. Fathers using food to control behavior had children with lower BMI percentiles. Conclusions Results indicate good initial validity and

  18. Experimental study of tube/support impact forces in multi-span PWR steam generator tubes

    International Nuclear Information System (INIS)

    Axisa, F.; Desseaux, A.; Gibert, R.J.

    1984-12-01

    The vibro-impact response of a straight part of a steam generator tube is investigated experimentally and using numerical simulation with the aim to relate tube overall dynamics with excitation and tube-support clearance. Configuration studied here corresponds to the tube being excited in only one direction at its first resonance presenting an antinode of vibration at the impacted support. Tests show namely that midspan displacement of tube is almost proportional to excitation level and clearance. Impact forces averaged over a cycle of vibration are almost proportional to excitation and poorly dependent on clearance. Results of numerical simulation are in fairly good agreement with test results

  19. Planet in a Test Tube

    Science.gov (United States)

    1995-01-01

    This composite image depicts one set of flow patterns simulated in the Geophysical Fluid Flow Cell (GFFC) that flew on two Spacelab missions. Silicone oil served as the atmosphere around a rotating steel hemisphere (dotted circle) and an electrostatic field pulled the oil inward to mimic gravity's effects during the experiments. The GFFC thus produced flow patterns that simulated conditions inside the atmospheres of Jupiter and the Sun and other stars. GFFC flew on Spacelab-3 in 1985 and U.S. Microgravity Laboratory-2 in 1995. The principal investigator was John Hart of the University of Colorado at Boulder. It was managed by NASA's Marshall Space Flight Center. (Credit: NASA/Marshall Space Flight Center)

  20. Sex in a test tube

    NARCIS (Netherlands)

    Pesce, Diego; Lehman, Niles; Visser, de Arjan

    2016-01-01

    The origin and evolution of sex, and the associated role of recombination, present a major problem in biology. Sex typically involves recombination of closely related DNA or RNA sequences,which is fundamentally a randomprocess that creates but also breaks up beneficial allele combinations.