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Sample records for test section parameters

  1. Cesarean section indications and anthropometric parameters in ...

    African Journals Online (AJOL)

    Concerned anthropometric parameters were height, weight and six pelvic distances. Fisher exact and Student's tests were used to compare observed proportions and mean values, respectively. Results: findings were as follows: 1) the overall cesarean section rate was 21.05%; 2) acute fetal distress (31.3 %), generally ...

  2. Vibroacoustic test plan evaluation: Parameter variation study

    Science.gov (United States)

    Stahle, C. V.; Gongloef, H. R.

    1976-01-01

    Statistical decision models are shown to provide a viable method of evaluating the cost effectiveness of alternate vibroacoustic test plans and the associated test levels. The methodology developed provides a major step toward the development of a realistic tool to quantitatively tailor test programs to specific payloads. Testing is considered at the no test, component, subassembly, or system level of assembly. Component redundancy and partial loss of flight data are considered. Most and probabilistic costs are considered, and incipient failures resulting from ground tests are treated. Optimums defining both component and assembly test levels are indicated for the modified test plans considered. modeling simplifications must be considered in interpreting the results relative to a particular payload. New parameters introduced were a no test option, flight by flight failure probabilities, and a cost to design components for higher vibration requirements. Parameters varied were the shuttle payload bay internal acoustic environment, the STS launch cost, the component retest/repair cost, and the amount of redundancy in the housekeeping section of the payload reliability model.

  3. Can quadruple test parameters predict SGA infants?

    Science.gov (United States)

    Güdücü, N; Gönenç, G; Işçi, H; Yiğiter, A Başgül; Dünder, I

    2013-04-01

    The aim of this study was to investigate the role of quadruple test parameters in predicting the risk of delivering a small for gestational age (SGA) infant. The quadruple test results of patients performed at 16-18 weeks of pregnancy were searched retrospectively. Alpha-fetoprotein (AFP) levels higher than 2 MoM were associated with a risk of delivering an SGA infant (p = 0.025), sensitivity 8%, specificity 98%, positive predictive value 25%, negative predictive value 91%. Other quadruple test parameters were not related to delivery of an SGA infant. The introduction of AFP as a screening test for the detection of SGA infants does not seem feasible, but we suggest clinicians take it into account when counselling the patients about the results of Down syndrome screening tests.

  4. Stand for testing sections of mechanized timbering

    Energy Technology Data Exchange (ETDEWEB)

    Grebennikov, Yu.N.; Aksenov, Yu.G.; Khazanov, Kh.I.; Khazin, V.A.; Radulov, V.Ye.; Vavilov, V.V.

    1982-01-01

    The purpose of the invention is to bring the testing conditions closer to the operating with multiple loading. This goal is achieved because in the stand for testing sections of mechanized timbering which includes a power frame, loading device with support and hydraulic equipment, the loading device is made in the form of enclosure sprockets and infinite mobile gears surrounding them on which with variable spacing with the help of transverse planks there are supports attached. In this case the length of the enclosure of each gear is the aliquant to the spacing of its advance.

  5. Cesarean section indications and anthropometric parameters in Rwandan nulliparae: preliminary results from a longitudinal survey.

    Science.gov (United States)

    Kakoma, Jean-Baptiste

    2016-01-01

    Maternal anthropometric parameters as risk factors for cesarean section have always been a matter of interest and concern for obstetricians. Some of these parameters have been shown to be predictors of dystocia. This study aims at showing the relationship between cesarean section indications and anthropometric parameters sizes in Rwandan nulliparae for the purpose of comparison and appropriate recommendations. A cross-sectional and analytical study was made on data collected from 32 operated patients among 152 nulliparae with singleton pregnancy at term and vertex presentation. Concerned anthropometric parameters were height, weight and six pelvic distances. Fisher exact and Student's tests were used to compare observed proportions and mean values, respectively. Findings were as follows: 1) the overall cesarean section rate was 21.05%; 2) acute fetal distress (31.3 %), generally contracted pelvis (28.1 %), and engagement failure (25%) were the most frequent indications of cesarean section; 3) all patients ≤ 145 cm tall were operated on for general pelvis contraction whose proportion was significantly higher in them than in the others (p difference with other weight categories was not significant; 5) considered external pelvic diameters but the Biiliac Diameter displayed average measurements smaller in clinically contracted pelvis than in other CS indications. External pelvimetry associated with specific other anthropometric parameters could be helpful in the screening of generally contracted pelves, and consequently pregnancies at high risk of cephalopelvic disproportion in nulliparous women, particularly in developing countries with limited resources. Further investigations are requested to deal with this topic in depth.

  6. On the consistency of bootstrap testing for a parameter on the boundary of the parameter space

    DEFF Research Database (Denmark)

    Cavaliere, Giuseppe; Nielsen, Heino Bohn; Rahbek, Anders

    2017-01-01

    It is well known that with a parameter on the boundary of the parameter space, such as in the classic cases of testing for a zero location parameter or no autoregressive conditional heteroskedasticity (ARCH) effects, the classic nonparametric bootstrap – based on unrestricted parameter estimates...... the standard and bootstrap Lagrange multiplier tests as well as the asymptotic quasi-likelihood ratio test....

  7. Testing linear models for ability parameters in item response models

    NARCIS (Netherlands)

    Glas, Cornelis A.W.; Hendrawan, I.

    2005-01-01

    Methods for testing hypotheses concerning the regression parameters in linear models for the latent person parameters in item response models are presented. Three tests are outlined: A likelihood ratio test, a Lagrange multiplier test and a Wald test. The tests are derived in a marginal maximum

  8. Testing for parameter instability across different modeling frameworks

    NARCIS (Netherlands)

    Calvori, Francesco; Creal, Drew; Koopman, Siem Jan; Lucas, André

    2017-01-01

    We develop a new parameter instability test that generalizes the seminal ARCHLagrange Multiplier test of Engle (1982) for a constant variance against the alternative of autoregressive conditional heteroskedasticity to settings with nonlinear timevarying parameters and non-Gaussian distributions. We

  9. Problems With Section Two ITP TOEFL Test

    Directory of Open Access Journals (Sweden)

    Rizki Ananda

    2016-03-01

    Full Text Available This study was designed to investigate (1 the difficulties faced by EFL university students with section two of the ITP, and (2 whether part A or part B was more difficult for them and why. A number of 26 students from two different universities, Syiah Kuala University and the State Islamic University Ar-Raniry were the samples for the test. The data was obtained from a multiple choice questionnaire test consisting of 46 questions, each with 4 answers to choose from. The results showed that inversions (12%, subject-verb agreements (10%, adverb clause connectors (7%, passives (6%, reduced adjective clauses (5%, parallel structures (5% and use of verbs (5% were the most difficult questions for the students. Furthermore, they felt that part B was more difficult than part A, as finding an error in a sentence was harder than completing a sentence from a multiple choice. Furthermore, the length of questions in part A did not affect the amount of time the students spent to complete part A and did not cause them to panic. Also, unfamiliar words in part A were not regarded as a problem by the students. Hence, TOEFL teachers and trainers are highly encouraged to pay more attention to doing study exercises for the seven topics with the highest percentages above in part A and also to more practice for part B.

  10. Evaluation Parameters for Computer-Adaptive Testing

    Science.gov (United States)

    Georgiadou, Elisabeth; Triantafillou, Evangelos; Economides, Anastasios A.

    2006-01-01

    With the proliferation of computers in test delivery today, adaptive testing has become quite popular, especially when examinees must be classified into two categories (passfail, master nonmaster). Several well-established organisations have provided standards and guidelines for the design and evaluation of educational and psychological testing.…

  11. A test for the parameters of multiple linear regression models ...

    African Journals Online (AJOL)

    A test for the parameters of multiple linear regression models is developed for conducting tests simultaneously on all the parameters of multiple linear regression models. The test is robust relative to the assumptions of homogeneity of variances and absence of serial correlation of the classical F-test. Under certain null and ...

  12. Algorithmic test design using classical item parameters

    OpenAIRE

    van der Linden, Willem J.; Adema, Jos J.

    1988-01-01

    Two optimalization models for the construction of tests with a maximal value of coefficient alpha are given. Both models have a linear form and can be solved by using a branch-and-bound algorithm. The first model assumes an item bank calibrated under the Rasch model and can be used, for instance, when classical test theory has to serve as an interface between the item bank system and a user not familiar with modern test theory. Maximization of alpha was obtained by inserting a special constra...

  13. Algorithmic test design using classical item parameters

    NARCIS (Netherlands)

    van der Linden, Willem J.; Adema, Jos J.

    Two optimalization models for the construction of tests with a maximal value of coefficient alpha are given. Both models have a linear form and can be solved by using a branch-and-bound algorithm. The first model assumes an item bank calibrated under the Rasch model and can be used, for instance,

  14. Problems With Section Two ITP TOEFL Test

    National Research Council Canada - National Science Library

    Rizki Ananda

    2016-01-01

    ...) whether part A or part B was more difficult for them and why. A number of 26 students from two different universities, Syiah Kuala University and the State Islamic University Ar-Raniry were the samples for the test...

  15. Hypothesis Testing of Parameters for Ordinary Linear Circular Regression

    Directory of Open Access Journals (Sweden)

    Abdul Ghapor Hussin

    2006-07-01

    Full Text Available This paper presents the hypothesis testing of parameters for ordinary linear circular regression model assuming the circular random error distributed as von Misses distribution. The main interests are in testing of the intercept and slope parameter of the regression line. As an illustration, this hypothesis testing will be used in analyzing the wind and wave direction data recorded by two different techniques which are HF radar system and anchored wave buoy.

  16. Algorithms for computerized test construction using classical item parameters

    OpenAIRE

    Adema, Jos J.; van der Linden, Willem J.

    1989-01-01

    Recently, linear programming models for test construction were developed. These models were based on the information function from item response theory. In this paper another approach is followed. Two 0-1 linear programming models for the construction of tests using classical item and test parameters are given. These models are useful, for instance, when classical test theory has to serve as an interface between an IRT-based item banking system and a test constructor not familiar with the und...

  17. Stereological parameters of carbides on section of casting made from modified chromium cast iron

    Directory of Open Access Journals (Sweden)

    A. Studnicki

    2011-07-01

    Full Text Available The analysis of stereological parameters of carbides on the section of the model castingmade from modified (the mixture FeNb+FeV+RE wear resistance chromium cast iron was introduced in the article. The jump change of some stereological parameters of carbides in certain distance from the surface of the casting was observed.

  18. Instrumental variables algorithm for modal parameter identification in flutter testing

    Science.gov (United States)

    Johnson, W.; Gupta, N. K.

    1978-01-01

    The paper is concerned with the task of estimating modal parameters from system response measurement in aircraft flutter testing. A frequency-domain derivation of an instrumental-variables algorithm is presented for a linear time-invariant dynamic system of order n. Basically, this algorithm fits a set of poles and zeros to the measured transfer function. An illustrative example is provided regarding the application of the algorithm to aeroelasticity testing. It is shown that the algorithm can be implemented for on-line data reduction with a microcomputer-based analysis system. By using instrumental variables the sensitivity of the modal parameter estimates to noise in the system-response measurements is reduced greatly. The algorithm is expected to be a powerful and valuable tool for on-line estimation of modal parameters in flutter testing and should be useful in control system and structural dynamics tests.

  19. Influence of the section size and holding time on the graphite parameters of ductile iron production

    Directory of Open Access Journals (Sweden)

    S. Bockus

    2009-01-01

    Full Text Available This work was conducted to establish the conditions required to produce a desirable structure of the castings of various section sizes. This investigation was focused on the study of the influence of cooling rate or section size and holding time on graphite parameters of the ductile iron. Plates having thickness between 3 and 50mm were cast in sand molds using the same melt. The present investigation has shown that the section size of ductile iron castings and holding time had strong effect on the graphite parameters of the castings.

  20. On Modal Parameter Estimates from Ambient Vibration Tests

    DEFF Research Database (Denmark)

    Agneni, A.; Brincker, Rune; Coppotelli, B.

    2004-01-01

    Modal parameter estimates from ambient vibration testing are turning into the preferred technique when one is interested in systems under actual loadings and operational conditions. Moreover, with this approach, expensive devices to excite the structure are not needed, since it can be adequately...

  1. Predicting Performance on a Firefighter's Ability Test from Fitness Parameters

    Science.gov (United States)

    Michaelides, Marcos A.; Parpa, Koulla M.; Thompson, Jerald; Brown, Barry

    2008-01-01

    The purpose of this project was to identify the relationships between various fitness parameters such as upper body muscular endurance, upper and lower body strength, flexibility, body composition and performance on an ability test (AT) that included simulated firefighting tasks. A second intent was to create a regression model that would predict…

  2. Lithium Disilicate Restorations Fatigue Testing Parameters: A Systematic Review.

    Science.gov (United States)

    Nawafleh, Noor; Hatamleh, Muhanad; Elshiyab, Shareen; Mack, Florian

    2016-02-01

    To review laboratory studies that investigated fatigue resistance of lithium disilicate (LD) crowns and fixed dental prostheses (FDPs) to elucidate study designs and testing parameters. An electronic search was performed in PubMed, Scopus, and Ovid to identify in vitro studies that investigated fatigue resistance of LD crowns and FDPs. The search included all studies published in English in peer-reviewed journals in the period from 1998 to June 2014. The search followed a specific strategy that included combination of the following keywords: lithium disilicate, e.max, empress, all-ceramic, all ceramic, glass ceramic, fatigue, cyclic loading, dynamic loading, chewing simulator, fracture resistance, thermocycling, laboratory simulation, aging, crown, FDPs, FPDs, fixed partial denture, fixed dental prosthesis, and bridge. Studies were selected if mechanical and thermal loading parameters were clearly identified. Search results with abstracts were transferred into Endnote reference system, and duplicates were deleted. The remaining studies were then reviewed at three levels (title, abstract, full text) to further refine the articles. The initial search retrieved 1044 eligible studies. After deduplication, 864 records were examined by titles and then abstracts; 826 were excluded, and 38 were assessed by full-text reading. In total, 19 articles met inclusion criteria and were included in this study. The studies reviewed showed a level of heterogeneity, as testing parameters were considered through different setups. The current study demonstrated that various setting of the testing parameters and having a lack of testing standardization has likely led to inconsistency in the reported results. The obvious heterogeneity in the setting of testing variables-especially the magnitude of load and number of cycles applied-made it impractical to run direct comparisons between the reviewed studies. Therefore, specific international standardization of fatigue testing of dental

  3. Vertical Drop Test of a Transport Fuselage Section

    OpenAIRE

    熊倉, 郁夫; KUMAKURA, Ikuo

    2002-01-01

    The NAL Structures and Materials Research Center conducted a vertical drop test of a fuselage section from a YS-11A transport airplane in December 2001. This test program is part of research into the structural crashworthiness of transport aircraft in the event of a crash accident, one of the subjects of Aviation Safety and Environmental Compatibility Technology Research(ASET) at NAL. Cooperative research related to this test program has also been carried out by NAL and Kawasaki Heavy Industr...

  4. Sanitary Landfill Simulation - Test Parameters and a Simulator Conceptual Design

    Science.gov (United States)

    1976-08-01

    ACSM -1~ for Nils ........... By L:R-yo/VAILaiL;1I CODES Library card Civil Engineering Laboratory SANITARY LANDFILL SIMULATION - TEST PARAMETERS AND...these landfills comply only marginally with Navy mandatory guidelines [2]. In a FY-74 report on this project [3], CEL presented the results of a...landfills are presently designed for burying solid waste in compliance with Environmental Protection Agency (EPA) operational guidelines . These

  5. Missile Aerodynamic Parameter and Structure Identification from Flight Test Data

    Science.gov (United States)

    1977-11-01

    predicted residual stand- ard derivation is an excellent test for proper filter behavior. The nxr matrix K. is the Kalman gain mati’ix. Let k x(t) denotte...MODEL AEhODYNAMIC MATHEMATICAL MODELo |.rrtrr . x Body Force AQC y Body Forco A0(CyR + Cy6 rAr) I "Body Force AQ(Cz ax + Cz6,6q) Moment About x 0 MOment...tion in angular motion offers an excellent test of the extended Kalman filter ability to identify parameters. Identification in I situations having

  6. Vertical Drop Test of a YS-11 Fuselage Section

    Science.gov (United States)

    Minegishi, Masakatsu; Kumakura, Ikuo; Iwasaki, Kazuo; Shoji, Hirokazu; Yoshimoto, Norio; Terada, Hiroyuki; Sashikuma, Hirofumi; Isoe, Akira; Yamaoka, Toshihiro; Katayama, Noriaki; Hayashi, Toru; Akaso, Tetsuya

    The Structures and Materials Research Center of the National Aerospace Laboratory of Japan (NAL) and Kawasaki Heavy Industories, Ltd. (KHI) conducted a vertical drop test of a fuselage section cut from a NAMIC YS-11 transport airplane at NAL vertical drop test facility in December 2001. The main objectives of this program were to obtain background data for aircraft cabin safety by drop test of a full-scale fuselage section and to develop computational method for crash simulation. The test article including seats and anthropomorphic test dummies was dropped to a rigid impact surface at a velocity of 6.1 m/s (20 ft/s). The test condition and result were considered to be severe but potentially survivable. A finite element model of this test article was also developed using the explicit nonlinear transient-dynamic analysis code, LS-DYNA3D. An outline of analytical method and comparison of analysis result with drop test data are presented in this paper.

  7. Comprehensive Amm242 neutron-induced reaction cross sections and resonance parameters

    Science.gov (United States)

    Buckner, M. Q.; Wu, C. Y.; Henderson, R. A.; Bucher, B.; Wimer, N.; Chyzh, A.; Bredeweg, T. A.; Baramsai, B.; Couture, A.; Jandel, M.; Mosby, S.; Ullmann, J. L.

    2017-06-01

    The 242Am metastable isomer's neutron-induced destruction mechanisms were studied at the Los Alamos Neutron Science Center using the Detector for Advanced Neutron-Capture Experiments array with a compact parallel-plate avalanche counter. New Amm242 neutron-capture cross sections were determined from 100 meV to 10 keV, and the absolute scale was set with respect to a concurrent measurement of the well-known Amm242 neutron-induced-fission cross section. The new fission cross section spans an energy range from 100 meV to 1 MeV and was normalized to the ENDF/B-VII.1 evaluated cross section to set the absolute scale. Our Amm242(n ,f ) cross section agrees well with the cross section of Browne et al. [Phys. Rev. C 29, 2188 (1984)], 10.1103/PhysRevC.29.2188 over this large energy interval. The new neutron-capture cross section measurement complements and agrees well with our recent results reported below 1 eV in Buckner et al. [Phys. Rev. C 95, 024610 (2017)], 10.1103/PhysRevC.95.024610. This new work comprises the most comprehensive study of Amm242(n ,γ ) above thermal energy. Neutron-induced resonance energies and parameters were deduced with the sammy R -matrix code for incident neutron energies up to 45 eV, and the new average Γγ is 13 % higher than the evaluated average γ width.

  8. Analysis of a transport fuselage section drop test

    Science.gov (United States)

    Fasanella, E. L.; Hayduk, R. J.; Robinson, M. P.; Widmayer, E.

    1984-01-01

    Transport fuselage section drop tests provided useful information about the crash behavior of metal aircraft in preparation for a full-scale Boeing 720 controlled impact demonstration (CID). The fuselage sections have also provided an operational test environment for the data acquisition system designed for the CID test, and data for analysis and correlation with the DYCAST nonlinear finite-element program. The correlation of the DYCAST section model predictions was quite good for the total fuselage crushing deflection (22 to 24 inches predicted versus 24 to 26 inches measured), floor deformation, and accelerations for the floor and fuselage. The DYCAST seat and occupant model was adequate to approximate dynamic loading to the floor, but a more sophisticated model would be required for good correlation with dummy accelerations. Although a full-section model using only finite elements for the subfloor was desirable, constraints of time and computer resources limited the finite-element subfloor model to a two-frame model. Results from the two-frame model indicate that DYCAST can provide excellent correlation with experimental crash behavior of fuselage structure with a minimum of empirical force-deflection data representing structure in the analytical model.

  9. Parameter-free calculation of charge-changing cross sections at high energy

    Science.gov (United States)

    Suzuki, Y.; Horiuchi, W.; Terashima, S.; Kanungo, R.; Ameil, F.; Atkinson, J.; Ayyad, Y.; Cortina-Gil, D.; Dillmann, I.; Estradé, A.; Evdokimov, A.; Farinon, F.; Geissel, H.; Guastalla, G.; Janik, R.; Knoebel, R.; Kurcewicz, J.; Litvinov, Yu. A.; Marta, M.; Mostazo, M.; Mukha, I.; Nociforo, C.; Ong, H. J.; Pietri, S.; Prochazka, A.; Scheidenberger, C.; Sitar, B.; Strmen, P.; Takechi, M.; Tanaka, J.; Tanihata, I.; Vargas, J.; Weick, H.; Winfield, J. S.

    2016-07-01

    Charge-changing cross sections at high energies are expected to provide useful information on nuclear charge radii. No reliable theory to calculate the cross section has yet been available. We develop a formula using Glauber and eikonal approximations and test its validity with recent new data on carbon isotopes measured at around 900 A MeV. We first confirm that our theory reproduces the cross sections of 12,13,14C+12C consistently with the known charge radii. Next we show that the cross sections of C-1912 on a proton target are all well reproduced provided the role of neutrons is accounted for. We also discuss the energy dependence of the charge-changing cross sections.

  10. Neutron capture on (94)Zr: Resonance parameters and Maxwellian-averaged cross sections

    CERN Document Server

    Tagliente, G; Fujii, K; Abbondanno, U; Aerts, G; Alvarez, H; Alvarez-Velarde, F; Andriamonje, S; Andrzejewski, J; Audouin, L; Badurek, G; Baumann, P; Becvar, F; Belloni, F; Berthoumieux, E; Bisterzo, S; Calvino, F; Calviani, M; Cano-Ott, D; Capote, R; Carrapico, C; Cennini, P; Chepel, V; Chiaveri, E; Colonna, N; Cortes, G; Couture, A; Cox, J; Dahlfors, M; David, S; Dillmann, I; Domingo-Pardo, C; Dridi, W; Duran, I; Eleftheriadis, C; Embid-Segura, M; Ferrari, A; Ferreira-Marques, R; Furman, W; Gallino, R; Goncalves, I; Gonzalez-Romero, E; Gramegna, F; Guerrero, C; Gunsing, F; Haas, B; Haight, R; Heil, M; Herrera-Martinez, A; Jericha, E; Kappeler, F; Kadi, Y; Karadimos, D; Karamanis, D; Kerveno, M; Kossionides, E; Krticka, M; Lamboudis, C; Leeb, H; Lindote, A; Lopes, I; Lozano, M; Lukic, S; Marganiec, J; Marrone, S; Martinez, T; Massimi, C; Mastinu, P; Mengoni, A; Moreau, C; Mosconi, M; Neves, F; Oberhummer, H; O'Brien, S; Pancin, J; Papachristodoulou, C; Papadopoulos, C; Paradela, C; Patronis, N; Pavlik, A; Pavlopoulos, P; Perrot, L; Pigni, M.T; Plag, R; Plompen, A; Plukis, A; Poch, A; Praena, J; Pretel, C; Quesada, J; Rauscher, T; Reifarth, R; Rosetti, M; Rubbia, C; Rudolf, G; Rullhusen, P; Salgado, J; Santos, C; Sarchiapone, L; Savvidis, I; Stephan, C; Tain, J.L; Tassan-Got, L; Tavora, L; Terlizzi, R; Vannini, G; Vaz, P; Ventura, A; Villamarin, D; Vincente, M.C; Vlachoudis, V; Vlastou, R; Voss, F; Walter, S; Wiescher, M; Wisshak, K

    2011-01-01

    The neutron capture cross sections of the Zr isotopes play an important role in nucleosynthesis studies. The s-process reaction flow between the Fe seed and the heavier isotopes passes through the neutron magic nucleus (90)Zr and through (91,92,93,94)Zr, but only part of the flow extends to (96)Zr because of the branching point at (95)Zr. Apart from their effect on the s-process flow, the comparably small isotopic (n, gamma) cross sections make Zr also an interesting structural material for nuclear reactors. The (94)Zr (n, gamma) cross section has been measured with high resolution at the spallation neutron source n_TOF at CERN and resonance parameters are reported up to 60 keV neutron energy.

  11. Analysis of a Hybrid Wing Body Center Section Test Article

    Science.gov (United States)

    Wu, Hsi-Yung T.; Shaw, Peter; Przekop, Adam

    2013-01-01

    The hybrid wing body center section test article is an all-composite structure made of crown, floor, keel, bulkhead, and rib panels utilizing the Pultruded Rod Stitched Efficient Unitized Structure (PRSEUS) design concept. The primary goal of this test article is to prove that PRSEUS components are capable of carrying combined loads that are representative of a hybrid wing body pressure cabin design regime. This paper summarizes the analytical approach, analysis results, and failure predictions of the test article. A global finite element model of composite panels, metallic fittings, mechanical fasteners, and the Combined Loads Test System (COLTS) test fixture was used to conduct linear structural strength and stability analyses to validate the specimen under the most critical combination of bending and pressure loading conditions found in the hybrid wing body pressure cabin. Local detail analyses were also performed at locations with high stress concentrations, at Tee-cap noodle interfaces with surrounding laminates, and at fastener locations with high bearing/bypass loads. Failure predictions for different composite and metallic failure modes were made, and nonlinear analyses were also performed to study the structural response of the test article under combined bending and pressure loading. This large-scale specimen test will be conducted at the COLTS facility at the NASA Langley Research Center.

  12. Finite Element Analysis and Test Results Comparison for the Hybrid Wing Body Center Section Test Article

    Science.gov (United States)

    Przekop, Adam; Jegley, Dawn C.; Rouse, Marshall; Lovejoy, Andrew E.

    2016-01-01

    This report documents the comparison of test measurements and predictive finite element analysis results for a hybrid wing body center section test article. The testing and analysis efforts were part of the Airframe Technology subproject within the NASA Environmentally Responsible Aviation project. Test results include full field displacement measurements obtained from digital image correlation systems and discrete strain measurements obtained using both unidirectional and rosette resistive gauges. Most significant results are presented for the critical five load cases exercised during the test. Final test to failure after inflicting severe damage to the test article is also documented. Overall, good comparison between predicted and actual behavior of the test article is found.

  13. Cyriax's deep friction massage application parameters: Evidence from a cross-sectional study with physiotherapists.

    Science.gov (United States)

    Chaves, Paula; Simões, Daniela; Paço, Maria; Pinho, Francisco; Duarte, José Alberto; Ribeiro, Fernando

    2017-12-01

    Deep friction massage is one of several physiotherapy interventions suggested for the management of tendinopathy. To determine the prevalence of deep friction massage use in clinical practice, to characterize the application parameters used by physiotherapists, and to identify empirical model-based patterns of deep friction massage application in degenerative tendinopathy. observational, analytical, cross-sectional and national web-based survey. 478 physiotherapists were selected through snow-ball sampling method. The participants completed an online questionnaire about personal and professional characteristics as well as specific questions regarding the use of deep friction massage. Characterization of deep friction massage parameters used by physiotherapists were presented as counts and proportions. Latent class analysis was used to identify the empirical model-based patterns. Crude and adjusted odds ratios and 95% confidence intervals were computed. The use of deep friction massage was reported by 88.1% of the participants; tendinopathy was the clinical condition where it was most frequently used (84.9%) and, from these, 55.9% reported its use in degenerative tendinopathy. The "duration of application" parameters in chronic phase and "frequency of application" in acute and chronic phases are those that diverge most from those recommended by the author of deep friction massage. We found a high prevalence of deep friction massage use, namely in degenerative tendinopathy. Our results have shown that the application parameters are heterogeneous and diverse. This is reflected by the identification of two application patterns, although none is in complete agreement with Cyriax's description. Copyright © 2017 Elsevier Ltd. All rights reserved.

  14. The Relation Between Adult Dark Spermatogonia and Other Parameters of Fertility Potential in Cryptorchid Testes

    DEFF Research Database (Denmark)

    Thorup, Jørgen Mogens; Kvist, Kolja; Clasen-Linde, Erik

    2013-01-01

    The fertility potential of boys with cryptorchidism may be related to the number of adult dark spermatogonia per tubular transverse section in testicular biopsies taken at orchiopexy. Placental-like alkaline phosphatase positive gonocytes in testes within year 1 of life indicate preserved ability...... for germ cell transformation. We related these parameters to the total number of tubular germ cells and other factors associated with fertility potential.......The fertility potential of boys with cryptorchidism may be related to the number of adult dark spermatogonia per tubular transverse section in testicular biopsies taken at orchiopexy. Placental-like alkaline phosphatase positive gonocytes in testes within year 1 of life indicate preserved ability...

  15. Measurement of neutron total cross-section and resonance parameters of xenon

    Energy Technology Data Exchange (ETDEWEB)

    Skoy, V.R. [Department of Physics, Kyungpook National University, Daegu 702-701 (Korea, Republic of); Frank Laboratory of Neutron Physics, Joint Institute for Nuclear Research, 141980 Dubna, Moscow Region (Russian Federation); Wang, T.F. [Department of Physics, Kyungpook National University, Daegu 702-701 (Korea, Republic of); Kim, G.N. [Department of Physics, Kyungpook National University, Daegu 702-701 (Korea, Republic of)], E-mail: gnkim@knu.ac.kr; Oh, Y.D.; Cho, M.H.; Ko, I.S.; Namkung, W. [Department of Physics, Pohang University of Science and Technology, Pohang 790-784 (Korea, Republic of)

    2009-07-01

    We measured the neutron total cross-sections of natural xenon in the neutron energy region from 0.1 to 40 eV by using the time-of-flight method at the Pohang neutron facility, which consists of an electron linear accelerator, a water-cooled tantalum target with a water moderator, and a 12-m long time-of-flight path. A {sup 6}Li-ZnS(Ag) scintillator with a diameter of 12.5 cm and a thickness of 1.6 cm was used as a neutron detector. Notch filters composed of Co, In, Cd were used to estimate the background level and to calculate the neutron flight path length. The present measurement was compared with the existing experimental and the evaluated data. The resonance parameters of Xe isotopes were obtained from the transmission ratio by using the SAMMY code and were compared with other previous results.

  16. Biochemical methane potential (BMP) tests: Reducing test time by early parameter estimation.

    Science.gov (United States)

    Da Silva, C; Astals, S; Peces, M; Campos, J L; Guerrero, L

    2018-01-01

    Biochemical methane potential (BMP) test is a key analytical technique to assess the implementation and optimisation of anaerobic biotechnologies. However, this technique is characterised by long testing times (from 20 to >100days), which is not suitable for waste utilities, consulting companies or plants operators whose decision-making processes cannot be held for such a long time. This study develops a statistically robust mathematical strategy using sensitivity functions for early prediction of BMP first-order model parameters, i.e. methane yield (B 0 ) and kinetic constant rate (k). The minimum testing time for early parameter estimation showed a potential correlation with the k value, where (i) slowly biodegradable substrates (k≤0.1d -1 ) have a minimum testing times of ≥15days, (ii) moderately biodegradable substrates (0.1testing times between 8 and 15 days, and (iii) rapidly biodegradable substrates (k≥0.2d -1 ) have testing times lower than 7days. Copyright © 2017 Elsevier Ltd. All rights reserved.

  17. Utilization of Advanced Diagnostic Methods for Texture and Rut Depth Analysis on a Testing Pavement Section

    Directory of Open Access Journals (Sweden)

    Slabej Martin

    2015-05-01

    Full Text Available Qualitative characteristics of pavement in wide range reflects the pavement serviceability, which is a summary of the characteristics of the pavement, providing a fast, smooth, economical and especially safe driving of motor-vehicles. The target factor of pavement serviceability and safety of roads represents the quality of their surface properties. In the framework of research activities performed in the Research Centre founded under the auspices of University of Žilina, individual parameters of pavement serviceability were monitored by pavement surface scanning. This paper describes the creation of a 3D - road surface model and its analysis and evaluation from the viewpoint of two pavement serviceability parameters - the rut depth and texture. Measurements were performed on an experimental pavement section used contemporary in an Accelerated Pavement Testing experiment. The long-term goal is to ascertain functions predicting degradation of these two pavement serviceability parameters.

  18. Testing for one Generalized Linear Single Order Parameter

    DEFF Research Database (Denmark)

    Ellegaard, Niels Langager; Christensen, Tage Emil; Dyre, Jeppe

    We examine a linear single order parameter model for thermoviscoelastic relaxation in viscous liquids, allowing for a distribution of relaxation times. In this model the relaxation of volume and entalpy is completely described by the relaxation of one internal order parameter. In contrast to prior...... work the order parameter may be chosen to have a non-exponential relaxation. The model predictions contradict the general consensus of the properties of viscous liquids in two ways: (i) The model predicts that following a linear isobaric temperature step, the normalized volume and entalpy relaxation...

  19. Adaptive testing of Materials using Preisach Model Parameters Variations - Introductory Tests

    Directory of Open Access Journals (Sweden)

    Tomas Visnovec

    2004-01-01

    Full Text Available A new diagnostic method (MAT - Magnetic Adaptive Testing for non-destructive testing of ferromagnetic construction materials (i.e. iron based under mechanical stress is under development, [1]. The method is based on the investigation of the correlation between the mechanical load and the parameters of Preisach-like model describing magnetic properties of such materials as the differential permeability matrix. To get the set of model parameters needed, a number of minor hysteresis loops under defined exciting magnetic field strength waveform shape H(t, especially with constant field change rate dH(t/dt required (which implies the inducted voltage to be proportional to the differential permeability, is to be measured. The influence of initial magnetic state of the investigated material, algorithm of demagnetisation process, the slope of time dependence of exciting magnetic field on the signal-to-noise ratio and stability of the measured signal is discussed.

  20. Influence of selected test parameters on measured values during the MSCR test

    Science.gov (United States)

    Benešová, Lucie; Valentin, Jan

    2017-09-01

    One of today’s most commonly used test on a Dynamic Shear Rheometer (DSR) is the Multiple Stress Creep Recovery (MSCR) test. The test is described in the standard EN 16659, which is valid in the Czech Republic since October 2016. The principle of the test is based on repeated loading and recovering of a bitumen sample, according to which it is possible to determine the percentage of elastic recovery (R) and non-recoverable creep compliance (Jnr) of the bituminous binder. This method has been recently promoted as the most suitable test for assessing the resistance of bituminous binders to permanent deformation. The test is performed at higher temperatures and is particularly suitable for modified bituminous binders. The paper deals with the comparison of the different input parameters set on the DSR device - different levels of stress, temperature of test, the geometry of the measuring device and also a comparison of the results for a different number of loading cycles. The research study was focused mainly on modified bituminous binders, but to compare the MSCR test it is performed even with conventional paving grade binders.

  1. Uncertainties in the Item Parameter Estimates and Robust Automated Test Assembly

    Science.gov (United States)

    Veldkamp, Bernard P.; Matteucci, Mariagiulia; de Jong, Martijn G.

    2013-01-01

    Item response theory parameters have to be estimated, and because of the estimation process, they do have uncertainty in them. In most large-scale testing programs, the parameters are stored in item banks, and automated test assembly algorithms are applied to assemble operational test forms. These algorithms treat item parameters as fixed values,…

  2. Sunset dates of chemicals subject to final TSCA section 4: test requirements and related section 12(b) actions

    Science.gov (United States)

    This table lists all chemical substances and mixtures that are and/or have been the subject of final TSCA Section 4 test rules and/or TSCA Section 4 enforceable consent agreements/orders (ECAs) issued under the TSCA Existing Chemicals Testing Program.

  3. Parameter Estimation And Hypothesis Testing In A Two Epoch Dam ...

    African Journals Online (AJOL)

    Also computed along with the least square solution and statistical testing were the minimum detectable Bias (MDB) and the Bias to Noise Ratio (BNR). All tests and adjustments were carried out using MOVE 3 software along with the LEICA SKI Pro 2.1. From the results of the tests, only observation to Rover station RF 8 ...

  4. Algorithms for computerized test construction using classical item parameters

    NARCIS (Netherlands)

    Adema, Jos J.; van der Linden, Willem J.

    1989-01-01

    Recently, linear programming models for test construction were developed. These models were based on the information function from item response theory. In this paper another approach is followed. Two 0-1 linear programming models for the construction of tests using classical item and test

  5. Spatiotemporal gait parameters during dual task walking in need of care elderly and young adults. A cross-sectional study.

    Science.gov (United States)

    Agner, S; Bernet, J; Brülhart, Y; Radlinger, L; Rogan, S

    2015-12-01

    Up to now there have only been marginal data in the elderly in need of care regarding spatiotemporal gait parameters during single (ST) and dual tasking (DT). The aim of this study was to allocate data for gait speed, cadence and stride length cycle variability in the elderly in need of care and in young adults during ST and DT, to compare the two groups and to demonstrate the impact of ST and DT on gait parameters. This cross-sectional study investigated a group of 16 young healthy adults (mean age 23.0 ± 2.5 years) and a group of 16 elderly persons in need of care (mean age 85.5 ± 0.6 years). The RehaWatch system was used to collect the spatiotemporal gait parameters cadence, speed and stride length. The participants completed four different measurements during normal walking and fast walking during ST and DT over a walking distance of 20 m. The Wilcoxon rank sum test and Whitney-U test were used for statistical analysis. Gait speed (ST and DT: p gait variability (ST: p = 0.007, DT: p = 0.003) were significantly reduced in the elderly in need of care group compared to the young group. The gait speed in the elderly in need of care group decreased from normal to fast walking (ST = - 2.8%, DT = - 12.2%) compared to the young group (ST = 31.5%, DT = 25.2%). The results of this study are comparable with the results of existing studies, which investigated falling and non-falling participants. Elderly people in need of care cannot increase the normal gait speed.

  6. Optical parameters Determination for absolute luminosity and total cross section measurements in ATLAS

    CERN Document Server

    Cavalier, Sophie

    ALFA (Absolute Luminosity For ATLAS) aims at measuring the absolute luminosity for the ATLAS experiment with an incertitude down to 2-3 \\% and the total elastic cross section. The luminosity is related to the number of events, the highest the luminosity, the highest the number of events. This is, then, an important quantity for colliders like LHC (Large Hadron Collider). LHC is made of two beams circulating in two different beam pipes and colliding at four interaction points where the four physics experiments are located (ATLAS, CMS, ALICE, LHCb). ALFA detectors inserted into Roman Pots (RPs), have been placed around ATLAS at 240 m distance from the collision point (IP1) after six quadrupoles magnets and two dipoles defining the ALFA beam line which is part of the LHC ring.The detectors are made of scintillating optics fibers to catch elastic protons generated at IP1. These protons are tracked through the LHC magnets beam line which needs to be optimized in terms of optics parameters. We call high β optics, ...

  7. Test Station for Measuring Aluminum Tube Geometrical Parameters

    CERN Document Server

    Oansea, D; Gongadze, A L; Gostkin, M I; Dedovich, D V; Evtoukhovitch, P G; Comanescu, B; Kotov, S A; Necsoiu, T; Potrap, I N; Rogalev, E V; Tskhadadze, E G; Chelkov, G A

    2001-01-01

    A test station for quality control of aluminum tube outer diameter and wall thickness is presented. The tested tubes are used for drift detector assembly of ATLAS (LHC, CERN) muon system. The outer diameter and wall thickness of aluminium tubes are measured by means of noncontact optical and ultrasonic methods respectively with the accuracy of 3 {\\mu}m. The testing process is automatic and interacts with the production data base.

  8. Nonlinear Analysis and Preliminary Testing Results of a Hybrid Wing Body Center Section Test Article

    Science.gov (United States)

    Przekop, Adam; Jegley, Dawn C.; Rouse, Marshall; Lovejoy, Andrew E.; Wu, Hsi-Yung T.

    2015-01-01

    A large test article was recently designed, analyzed, fabricated, and successfully tested up to the representative design ultimate loads to demonstrate that stiffened composite panels with through-the-thickness reinforcement are a viable option for the next generation large transport category aircraft, including non-conventional configurations such as the hybrid wing body. This paper focuses on finite element analysis and test data correlation of the hybrid wing body center section test article under mechanical, pressure and combined load conditions. Good agreement between predictive nonlinear finite element analysis and test data is found. Results indicate that a geometrically nonlinear analysis is needed to accurately capture the behavior of the non-circular pressurized and highly-stressed structure when the design approach permits local buckling.

  9. Parameter testing for lattice filter based adaptive modal control systems

    Science.gov (United States)

    Sundararajan, N.; Williams, J. P.; Montgomery, R. C.

    1983-01-01

    For Large Space Structures (LSS), an adaptive control system is highly desirable. The present investigation is concerned with an 'indirect' adaptive control scheme wherein the system order, mode shapes, and modal amplitudes are estimated on-line using an identification scheme based on recursive, least-squares, lattice filters. Using the identified model parameters, a modal control law based on a pole-placement scheme with the objective of vibration suppression is employed. A method is presented for closed loop adaptive control of a flexible free-free beam. The adaptive control scheme consists of a two stage identification scheme working in series and a modal pole placement control scheme. The main conclusion from the current study is that the identified parameters cannot be directly used for controller design purposes.

  10. Test verification and design of the bicycle frame parameters

    Science.gov (United States)

    Zhang, Long; Xiang, Zhongxia; Luo, Huan; Tian, Guan

    2015-07-01

    Research on design of bicycles is concentrated on mechanism and auto appearance design, however few on matches between the bike and the rider. Since unreasonable human-bike relationship leads to both riders' worn-out joints and muscle injuries, the design of bicycles should focus on the matching. In order to find the best position of human-bike system, simulation experiments on riding comfort under different riding postures are done with the lifemode software employed to facilitate the cycling process as well as to obtain the best position and the size function of it. With BP neural network and GA, analyzing simulation data, conducting regression analysis of parameters on different heights and bike frames, the equation of best position of human-bike system is gained at last. In addition, after selecting testers, customized bikes based on testers' height dimensions are produced according to the size function. By analyzing and comparing the experimental data that are collected from testers when riding common bicycles and customized bicycles, it is concluded that customized bicycles are four times even six times as comfortable as common ones. The equation of best position of human-bike system is applied to improve bikes' function, and the new direction on future design of bicycle frame parameters is presented.

  11. Correlation between thromboelastography and traditional coagulation test parameters in hospitalized dogs

    Directory of Open Access Journals (Sweden)

    Rubanick JV

    2017-02-01

    Full Text Available Jean V Rubanick, Medora B Pashmakova, Micah A Bishop, James W Barr Department of Veterinary Small Animal Clinical Sciences, Texas A&M University, College Station, TX, USA Abstract: A hospital-based, prospective cross-sectional study was used to compare kaolin-activated thromboelastography (TEG parameters with traditional coagulation tests in 29 hospitalized dogs. Cases were included if the attending clinician requested coagulation testing. Blood was obtained from each dog and coagulation (prothrombin time, partial thromboplastin time, antithrombin activity, d-dimer concentration, and fibrinogen concentration and TEG analyses were performed. Hematocrit (Hct was also measured. Traditional coagulation results were evaluated for correlation with those from kaolin-activated TEG. Spearman’s correlation was used to calculate correlation coefficients. Fibrinogen was positively correlated with maximum amplitude (Pearson r=0.72, P<0.001 and global clot strength (Pearson r=0.72, P<0.001. There was no correlation between any of the remaining coagulation variables, TEG parameters, or Hct. Results of kaolin-activated TEG and traditional coagulation tests are not interchangeable means of monitoring coagulation derangements in this intensive care unit patient population. Determination of a true outcome measure is necessary to establish TEG’s clinical relevance to veterinary medicine. Keywords: TEG, thromboelastography, coagulation, hemostasis

  12. 16 CFR 1211.5 - General testing parameters.

    Science.gov (United States)

    2010-01-01

    ... § 1211.15(i) and (k). (7) When the Demonstrated Method Test is conducted, the multiplier is to be based... condition flow chart shown in figure 1 shall be used: (1) To conduct a failure-mode and effect analysis...

  13. The Effect of Scale Referent on Tests of Mean Structure Parameters

    Science.gov (United States)

    Kang, Yoonjeong; Hancock, Gregory R.

    2017-01-01

    Structured means analysis is a very useful approach for testing hypotheses about population means on latent constructs. In such models, a z test is most commonly used for testing the statistical significance of the relevant parameter estimates or of the differences between parameter estimates, where a z value is computed based on the asymptotic…

  14. Flight test diagnostics using radar cross-section measurements

    Science.gov (United States)

    Kao, P. S. S.; Anderson, W. F.

    1981-11-01

    An automated radar cross-section (RCS) measurement system is described, which features windband coverage, coherent step-frequency measurement, polarization diversity, waveform flexibility, and on-site digital processing. A computer-aided diagnostic technique to facilitate preflight planning and post-mission analyses is also discussed, and applications of the combined capabilities of both systems are considered. It is demonstrated that interactive RCS tailoring of a vehicle's backscatter cross-section improves the collection of radar data, allows post-flight motion extraction on small instrument vehicles, and makes possible the diagnosis of a vehicles endo-atmospheric dynamics to check the aerodynamic coefficient.

  15. Calculation of (n,α reaction cross sections by using some Skyrme force parameters for Potassium (41K target nuclei

    Directory of Open Access Journals (Sweden)

    Tel Eyyup

    2017-01-01

    Full Text Available In this study, the (n,α nuclear reaction cross section was calculated for 41K target nuclei for neutron and proton density parameters using SKa, SKb, SLy5, and SLy6 Skyrme force. Theoretical cross section for the (n,α nuclear reaction was obtained using a formula constituted by Tel et al. (2008. Results are compared with experimental data from EXFOR. The calculated results from formula was found in a close agreement with experimental data.

  16. Calculation of (n,α) reaction cross sections by using some Skyrme force parameters for Potassium (41K) target nuclei

    Science.gov (United States)

    Tel, Eyyup; Sahan, Muhittin; Alkanli, Hasancan; Sahan, Halide; Yigit, Mustafa

    2017-09-01

    In this study, the (n,α) nuclear reaction cross section was calculated for 41K target nuclei for neutron and proton density parameters using SKa, SKb, SLy5, and SLy6 Skyrme force. Theoretical cross section for the (n,α) nuclear reaction was obtained using a formula constituted by Tel et al. (2008). Results are compared with experimental data from EXFOR. The calculated results from formula was found in a close agreement with experimental data.

  17. Genetic parameters of test day milk yields of Holstein cows

    Directory of Open Access Journals (Sweden)

    S.G. Machado

    1999-09-01

    Full Text Available Data were obtained from 17,968 records from 2,130 first lactations of Holstein cows calving between 1988 and 1991. The subjects were daughters of 136 sires monitored by Brazilian Breeders Association, Animal Science Institute, Department of Agriculture, a branch of the State of São Paulo. Data were divided into 10 subsets based on the number of days in milk yield. Test day milk yields (M1 to M10 and 305-day milk yield (M305 were the traits studied. These traits were adjusted for several environmental effects: class of cow age at calving, interval from calving to first test day, and herd-year-season. Restricted maximum likelihood estimates of (covariance components were obtained from one and two-traits analysis under a sire model. Estimates of heritabilities for M ranged from 0.04 to 0.32. The highest values were found in the second half of lactation (M5 to M7. Heritability estimate for M305 was 0.32. Genetic correlations between individual test days and M305 ranged from 0.78 to 1.00. Results suggested that test day milk yields, mainly in mid-lactation, can be used instead of 305-day milk yield in genetic evaluations, because estimates of these two-trait heritabilities are nearly alike. Moreover, early selection can reduce generation intervals.No presente estudo foram utilizados 17.968 registros de produção de leite, referentes a 2130 primeiras lactações de vacas da raça Holandesa, paridas nos anos de 1988 a 1991, filhas de 136 touros e controladas pela Associação Brasileira de Criadores (ABC. Os dados foram distribuídos em dez sub-arquivos de acordo com o número do controle (M1 a M10. As características estudadas foram: produção de leite no dia do controle (M e produção aos 305 dias de lactação (M305, as quais foram ajustadas para os seguintes fatores de variação: idade da vaca ao parto em classes, intervalo parto-primeiro controle e subclasses de rebanho-ano-estação de parto. Os componentes de (covariância foram obtidos a

  18. Correlation analysis between pulmonary function test parameters and CT image parameters of emphysema

    Science.gov (United States)

    Liu, Cheng-Pei; Li, Chia-Chen; Yu, Chong-Jen; Chang, Yeun-Chung; Wang, Cheng-Yi; Yu, Wen-Kuang; Chen, Chung-Ming

    2016-03-01

    Conventionally, diagnosis and severity classification of Chronic Obstructive Pulmonary Disease (COPD) are usually based on the pulmonary function tests (PFTs). To reduce the need of PFT for the diagnosis of COPD, this paper proposes a correlation model between the lung CT images and the crucial index of the PFT, FEV1/FVC, a severity index of COPD distinguishing a normal subject from a COPD patient. A new lung CT image index, Mirage Index (MI), has been developed to describe the severity of COPD primarily with emphysema disease. Unlike conventional Pixel Index (PI) which takes into account all voxels with HU values less than -950, the proposed approach modeled these voxels by different sizes of bullae balls and defines MI as a weighted sum of the percentages of the bullae balls of different size classes and locations in a lung. For evaluation of the efficacy of the proposed model, 45 emphysema subjects of different severity were involved in this study. In comparison with the conventional index, PI, the correlation between MI and FEV1/FVC is -0.75+/-0.08, which substantially outperforms the correlation between PI and FEV1/FVC, i.e., -0.63+/-0.11. Moreover, we have shown that the emphysematous lesion areas constituted by small bullae balls are basically irrelevant to FEV1/FVC. The statistical analysis and special case study results show that MI can offer better assessment in different analyses.

  19. Exercise testing parameters associated with post lung transplant mortality.

    Science.gov (United States)

    Armstrong, Hilary F; Garber, Carol Ewing; Bartels, Matthew N

    2012-04-30

    Exercise performance during cardiopulmonary exercise testing (CPET) is a predictor of all-cause mortality in the general population and in patients with coronary heart disease. Mortality beyond one-year after lung transplantation (LTx) is due to multiple causes, is difficult to predict, and has not been fully evaluated in LTx recipients. We hypothesized that, similar to other populations, exercise performance after LTx may be associated with mortality. A retrospective review of all LTx recipients who underwent CPET between 2001 and 2009 was conducted. Chosen endpoint was re-transplantation or death. Survival analysis was performed using Cox proportional-hazard models in 183 patients. After adjusting for bronchiolitis obliterans syndrome (BOS) score, for every 10% increment in percent-predicted peak watts or percent-predicted peak oxygen uptake patients were approximately 23% less likely to experience an endpoint. We conclude that after adjusting for BOS score, lower exercise capacity one-year post LTx is independently associated with mortality. This may imply a protective role of exercise capacity in the LTx population. Copyright © 2012 Elsevier B.V. All rights reserved.

  20. Influence of the vibratory test facility type and parameters upon the cavitation erosion evolution

    Science.gov (United States)

    Bordeasu, I.; Popoviciu, M. O.; Balasoiu, V.; Jurchela, A. D.; Karabenciov, A.

    2010-08-01

    Paper analyses the configuration of area and depth for the laboratory produced cavitation erosion. The affected zones were examined using both an optic microscope and a device for obtaining the cross-sectional profile of the eroded area. The cavitation was produced with a nickel tube magnetostrictive device (vibration amplitude 94 μm, vibration frequency 7 kHz, specimen diameter 14 mm and power 500 W) as well as with a standard piezoceramic crystals device (vibration amplitude 50 μm, vibration frequency 20 kHz, specimen diameter 16 mm and the power 500 W). The test specimens were manufactured from two different materials (steel and bronze). We found that the vibrations amplitude has greater influence upon the erosion (we obtained increase in the erosion maximum depth, in the total eroded mass and in the erosion velocity). Regardless of the running parameters, the way in which the deformations, the cracks and the dislocations are produced, is very similar.

  1. A Stepwise Test Characteristic Curve Method to Detect Item Parameter Drift

    Science.gov (United States)

    Guo, Rui; Zheng, Yi; Chang, Hua-Hua

    2015-01-01

    An important assumption of item response theory is item parameter invariance. Sometimes, however, item parameters are not invariant across different test administrations due to factors other than sampling error; this phenomenon is termed item parameter drift. Several methods have been developed to detect drifted items. However, most of the…

  2. Effect of Pesticide Exposure on Immunological, Hematological and Biochemical Parameters in Thai Orchid Farmers—A Cross-Sectional Study

    Science.gov (United States)

    Aroonvilairat, Soraya; Kespichayawattana, Wannapa; Sornprachum, Thiwaree; Chaisuriya, Papada; Siwadune, Taweeratana; Ratanabanangkoon, Kavi

    2015-01-01

    Various studies have found that many Thai orchid farmers used excessive amounts of pesticides without proper protective gear, but no toxicological study has been made. This cross-sectional study aimed to evaluate the immunological, hematological and biochemical statuses of these farmers. Sixty four orchid farmers and 60 controls were studied. Plasma cholinesterase activity, the percentage and absolute number of B lymphocytes (CD19+) were significantly lower in the farmers group (3966.32 ± 1165.48 U/L, 11.61 ± 4.09% and 312.26 ± 164.83 cells/mm3, respectively) as compared to those of controls (5048.85 ± 1139.40 U/L, 14.32 ± 4.23%, 420.34 ± 195.18 cells/mm3, respectively). There was a statistically significant higher level of serum IgE among the orchid farmers (0.031 ± 0.011 mg/dL vs. 0.018 ± 0.007 mg/dL) but not IgG, IgA and IgM, levels. Serum lysozyme level, lymphocyte proliferative responses to mitogens, hematological parameters and kidney function test, were not significantly different between the two groups. The liver function profiles showed significantly lower levels of albumin and serum protein in the farmer group. Thus frequent pesticide exposure resulted in subtle changes of some biological parameters. These changes, though may not be clinically significant, strongly indicated that caution in handing pesticides by these farmers is warranted. PMID:26024358

  3. Wall Correction Model for Wind Tunnels with Open Test Section

    DEFF Research Database (Denmark)

    Sørensen, Jens Nørkær; Shen, Wen Zhong; Mikkelsen, Robert Flemming

    2004-01-01

    In th paper we present a correction model for wall interference on rotors of wind turbines or propellers in wind tunnels. The model, that is based on a onedimensional momentum approach, is validated against results from CFD computations using a generalized actuator disc principle. Generally......, the corrections from the model are in very good agreement with the CFD computaions, demonstrating that one-dimensional momentum theory is a reliable way of predicting corrections for wall interference in wind tunnels with closed as well as open cross sections. Keywords: Wind tunnel correction, momentum theory...

  4. Supersonic Retropropulsion Test 1853 in NASA LaRC Unitary Plan Wind Tunnel Test Section 2

    Science.gov (United States)

    Berry, Scott A.; Rhode, Matthew N.

    2014-01-01

    A supersonic retropropulsion experiment was conducted in the Langley Research Center Unitary Plan Wind Tunnel Test Section 2 at Mach numbers of 2.4, 3.5, and 4.6. Intended as a code validation effort, this study used pretest computations to size and refine the model such that tunnel blockage and internal flow separations were minimized. A 5-in diameter 70 degree sphere-cone forebody, which can accommodate up to four 4:1 area ratio nozzles, followed by a 9.55 inches long cylindrical aft body was selected for this test after computational maturation. The primary measurements for this experiment were high spatial-density surface pressures. In addition, high speed schlieren video and internal pressures and temperatures were acquired. The test included parametric variations in the number of nozzles utilized, thrust coefficients (roughly 0 to 4), and angles of attack (-8 to 20 degrees). The run matrix was developed to also allow quantification of various sources of experimental uncertainty, such as random errors due to run-to-run variations and systematic errors due to flowfield or model misalignments. To accommodate the uncertainty assessment, many runs and replicates were conducted with the model at various locations within the tunnel and with model roll angles of 0, 60, 120, and 180 degrees. This test report provides operational details of the experiment, contains a review of trends, and provides all schlieren and pressure results within appendices.

  5. Overview of the computerized adaptive testing special section

    Directory of Open Access Journals (Sweden)

    Vicente Ponsoda

    2000-01-01

    Full Text Available Presentación de la sección monográfica sobre test adaptativos informatizados. Este artículo proporciona una visión conjunta de la sección especial de Psicológica sobre tests adaptativos informatizados. Se presenta también una breve introducción al tema. De cada artículo se muestran sus principales resultados, las conexiones con los demás trabajos de la sección especial y el tema de investigación con el que está más relacionado.

  6. Wall correction model for wind tunnels with open test section

    DEFF Research Database (Denmark)

    Sørensen, Jens Nørkær; Shen, Wen Zhong; Mikkelsen, Robert Flemming

    2006-01-01

    In the paper we present a correction model for wall interference on rotors of wind turbines or propellers in wind tunnels. The model, which is based on a one-dimensional momentum approach, is validated against results from CFD computations using a generalized actuator disc principle. In the model...... the exchange of axial momentum between the tunnel and the ambient room is represented by a simple formula, derived from actuator disc computations. The correction model is validated against Navier-Stokes computations of the flow about a wind turbine rotor. Generally, the corrections from the model are in very...... good agreement with the CFD computations, demonstrating that one-dimensional momentum theory is a reliable way of predicting corrections for wall interference in wind tunnels with closed as well as open cross sections....

  7. Evaluation of geostatistical parameters based on well tests; Estimation de parametres geostatistiques a partir de tests de puits

    Energy Technology Data Exchange (ETDEWEB)

    Gauthier, Y.

    1997-10-20

    Geostatistical tools are increasingly used to model permeability fields in subsurface reservoirs, which are considered as a particular random variable development depending of several geostatistical parameters such as variance and correlation length. The first part of the thesis is devoted to the study of relations existing between the transient well pressure (the well test) and the stochastic permeability field, using the apparent permeability concept.The well test performs a moving permeability average over larger and larger volume with increasing time. In the second part, the geostatistical parameters are evaluated using well test data; a Bayesian framework is used and parameters are estimated using the maximum likelihood principle by maximizing the well test data probability density function with respect to these parameters. This method, involving a well test fast evaluation, provides an estimation of the correlation length and the variance over different realizations of a two-dimensional permeability field

  8. Neutron total cross-sections and resonance parameters of Mo and Ta

    Indian Academy of Sciences (India)

    better energy resolutions for the channel widths of the data saving systems. The detailed explanations of the data ... Then the energy resolution can be written by the expression as. Pramana – J. Phys., Vol. 68, No. .... Resonance parameters of Ta-181 isotope obtained by this evaluation with Christensen [13], Harvey et al ...

  9. Documentation of Stainless Steel Lithium Circuit Test Section Design. Suppl

    Science.gov (United States)

    Godfroy, Thomas J. (Compiler); Martin, James J.

    2010-01-01

    The Early Flight Fission-Test Facilities (EFF-TF) team was tasked by Naval Reactors Prime Contract Team (NRPCT) to design, fabricate, and test an actively pumped lithium (Li) flow circuit. This Li circuit takes advantage of work in progress at the EFF TF on a stainless steel sodium/potassium (NaK) circuit. The effort involved modifying the original stainless steel NaK circuit such that it could be operated with Li in place of NaK. This new design considered freeze/thaw issues and required the addition of an expansion tank and expansion/extrusion volumes in the circuit plumbing. Instrumentation has been specified for Li and circuit heaters have been placed throughout the design to ensure adequate operational temperatures and no uncontrolled freezing of the Li. All major components have been designed and fabricated prior to circuit redesign for Li and were not modified. Basic circuit components include: reactor segment, Li to gas heat exchanger, electromagnetic liquid metal pump, load/drain reservoir, expansion reservoir, instrumentation, and trace heaters. The reactor segment, based on a Los Alamos National Laboratory 100-kW design study with 120 fuel pins, is the only prototypic component in the circuit. However, due to earlier funding constraints, a 37-pin partial-array of the core, including the central three rings of fuel pins (pin and flow path dimensions are the same as those in the full design), was selected for fabrication and test. This Technical Publication summarizes the design and integration of the pumped liquid metal Li flow circuit as of May 1, 2005. This supplement contains drawings, analysis, and calculations

  10. Experimental and Theoretical Study of Air Flow with Obstruction Through Test Section of Wind Tunnel

    Directory of Open Access Journals (Sweden)

    Hayder Kraidy Rashid

    2016-03-01

    Full Text Available This paper estimates the sound and flow generated by a turbulent air flow in a duct from the knowledge of mean quantities (average velocity and sound pressure level.The sound excitation by fluid flow through duct can be used to predict fluid behavior. This behavior can be carried out by discovering the relation between sound excitation and fluid flow parameters like Reynolds number, Strouhal number and frequencies of turbulent fluid flow. However, the fluid flow container stability has to be taken in account simultaneously with fluid flow effect on sound generation and propagation. The experimental system used in this work is air flow through subsonic wind tunnel duct.The sound pressure levels of air flows through test section of subsonic wind tunnel (at three air flow velocities2.5, 7.3 and 12.5 m/s respectively were carried out experimentally. The sound excitation or generation by air flow throughout the test section of subsonic wind tunnel without any obstruction can't be used to imagine the fluid behavior. To predict fluid flow properties,an infinite cylinder was immersed in order to obstruct the air flow and generate a new source of sound.This case is relevant to a wide range of engineering applications including aircraft landing gear, rail pantographs and automotive side-mirrors. Sound measurements have been taken in an anechoic room at Babylon University. ANSYS program software is used to simulate all experimental results.The experimental and theoretical data that were presented in this paper will give further insight into the underlying sound generation mechanism.In the presented work, the linkage between sound generation and CFD results using thepresented work results and ANSYS simulation results was done.The results discuss the effects of fluid flow parameters such as Reynolds and Strouhal numbers on the sound generation, propagation features and vice-versa. The results are compared with other researchers which give good agreements.

  11. Using Combined Diagnostic Test Results to Hindcast Trends of Infection from Cross-Sectional Data.

    Directory of Open Access Journals (Sweden)

    Gustaf Rydevik

    2016-07-01

    Full Text Available Infectious disease surveillance is key to limiting the consequences from infectious pathogens and maintaining animal and public health. Following the detection of a disease outbreak, a response in proportion to the severity of the outbreak is required. It is thus critical to obtain accurate information concerning the origin of the outbreak and its forward trajectory. However, there is often a lack of situational awareness that may lead to over- or under-reaction. There is a widening range of tests available for detecting pathogens, with typically different temporal characteristics, e.g. in terms of when peak test response occurs relative to time of exposure. We have developed a statistical framework that combines response level data from multiple diagnostic tests and is able to 'hindcast' (infer the historical trend of an infectious disease epidemic. Assuming diagnostic test data from a cross-sectional sample of individuals infected with a pathogen during an outbreak, we use a Bayesian Markov Chain Monte Carlo (MCMC approach to estimate time of exposure, and the overall epidemic trend in the population prior to the time of sampling. We evaluate the performance of this statistical framework on simulated data from epidemic trend curves and show that we can recover the parameter values of those trends. We also apply the framework to epidemic trend curves taken from two historical outbreaks: a bluetongue outbreak in cattle, and a whooping cough outbreak in humans. Together, these results show that hindcasting can estimate the time since infection for individuals and provide accurate estimates of epidemic trends, and can be used to distinguish whether an outbreak is increasing or past its peak. We conclude that if temporal characteristics of diagnostics are known, it is possible to recover epidemic trends of both human and animal pathogens from cross-sectional data collected at a single point in time.

  12. An alternative approach to absolute-value test for the parameters of ...

    African Journals Online (AJOL)

    An alternative approach to absolute-value test statistic Mn is developed for conducting tests simultaneously on all the parameters of multiple linear regression models. Under certain null and alternative hypotheses, the new test statistic is shown to have limiting central and noncentral chisquare distributions, respectively.

  13. An Empirical Test of Roskam's Conjecture about the Interpretation of an ICC Parameter in Personality Inventories.

    Science.gov (United States)

    Zumbo, Bruno D.; Pope, Gregory A.; Watson, Jackie E.; Hubley, Anita M.

    1997-01-01

    E. Roskam's (1985) conjecture that steeper item characteristic curve (ICC) "a" parameters (slopes) (and higher item total correlations in classical test theory) would be found with more concretely worded test items was tested with results from 925 young adults on the Eysenck Personality Questionnaire (H. Eysenck and S. Eysenck, 1975).…

  14. Construction and monitoring of thin overlay and crack sealant test sections at the Pecos test track.

    Science.gov (United States)

    2014-10-01

    In this project, several crack sealant sections were constructed at the Pecos RTC. Six different sealants were : applied in routed and non-routed configurations on both older and newer pavement. The following summer, : the sections were revaluated in...

  15. Baseline blood trihalomethanes, semen parameters and serum total testosterone: a cross-sectional study in China.

    Science.gov (United States)

    Zeng, Qiang; Li, Min; Xie, Shao-Hua; Gu, Long-Jie; Yue, Jing; Cao, Wen-Cheng; Zheng, Dan; Liu, Ai-Lin; Li, Yu-Feng; Lu, Wen-Qing

    2013-04-01

    Toxicological studies showed that trihalomethanes (THMs), the most abundant classes of disinfection by-products (DBPs) in drinking water, impaired male reproductive health, but epidemiological evidence is limited and inconsistent. This study aimed to examine the associations of baseline blood THMs with semen parameters and serum total testosterone in a Chinese population. We recruited 401 men seeking semen examination from the Reproductive Center of Tongji Hospital in Wuhan, China between April 2011 and May 2012. Baseline blood concentrations of THMs, including chloroform (TCM), bromodichloromethane (BDCM), dibromochloromethane (DBCM), and bromoform (TBM) were measured using SPME-GC/ECD method. Semen quality and serum total testosterone were analyzed. Multivariable linear regressions were used to assess the associations of baseline blood THM concentrations with semen parameters and serum total testosterone levels. We found that baseline blood THM concentrations were not associated with decrements in sperm motility, sperm straight-line and curvilinear velocity. However, moderate levels of BDCM (β=-0.13 million; 95% CI: -0.22, -0.03) and DBCM (β=-4.74%; 95% CI: -8.07, -1.42) were associated with decreased sperm count and declined sperm linearity compared with low levels, respectively. Suggestive dose-response relationships were also observed between elevated blood TCM or ∑ THMs (sum of TCM, BDCM, DBCM and TBM) concentration and decreased sperm concentration (both p for trend=0.07), and between elevated blood DBCM concentration and decreased serum total testosterone (p for trend=0.07). Our results indicate that elevated THM exposure may lead to decreased sperm concentration and serum total testosterone. However, the effects of THM exposure on male reproductive health still warrant further studies in humans. Copyright © 2013 Elsevier Ltd. All rights reserved.

  16. Genetic parameters for test-day milk yield in tropical Holstein ...

    African Journals Online (AJOL)

    Accurate estimates of genetic parameters are essential for genetic improvement of milk yield in dairy cattle and for setting up breeding programmes. Estimates of genetic parameters from test-day models, particularly for Holstein Friesian cattle maintained in tropical environments, are scant in the literature. The objective of ...

  17. Lumped Parameter Modeling for Rapid Vibration Response Prototyping and Test Correlation for Electronic Units

    Science.gov (United States)

    Van Dyke, Michael B.

    2013-01-01

    Present preliminary work using lumped parameter models to approximate dynamic response of electronic units to random vibration; Derive a general N-DOF model for application to electronic units; Illustrate parametric influence of model parameters; Implication of coupled dynamics for unit/board design; Demonstrate use of model to infer printed wiring board (PWB) dynamics from external chassis test measurement.

  18. Nonlinear Parameter Estimation in Microbiological Degradation Systems and Statistic Test for Common Estimation

    DEFF Research Database (Denmark)

    Sommer, Helle Mølgaard; Holst, Helle; Spliid, Henrik

    1995-01-01

    and the growth of the biomass are described by the Monod model consisting of two nonlinear coupled first-order differential equations. The objective of this study was to estimate the kinetic parameters in the Monod model and to test whether the parameters from the three identical experiments have the same values...

  19. Establishing Relationships between Parameters of the Controlled Compaction Soil by Using Various In-Situ Tests

    Science.gov (United States)

    Wyroslak, Mariusz

    2017-10-01

    The aim of research was evaluating reliable correlations between chosen soil parameters describing state of surface layers of soil. The paper presents site comparative tests based on the light falling weight deflectometer (LFWD), the static plate load tester (VSS), the dynamic probing light tester (DPL) and the bearing ratio tester (CBR in-situ) with relationships between soil state parameters. All featured in-situ tests were conducted based on Polish experiences and Standards used in engineering practice.

  20. Study on Identification of Material Model Parameters from Compact Tension Test on Concrete Specimens

    Science.gov (United States)

    Hokes, Filip; Kral, Petr; Husek, Martin; Kala, Jiri

    2017-10-01

    Identification of a concrete material model parameters using optimization is based on a calculation of a difference between experimentally measured and numerically obtained data. Measure of the difference can be formulated via root mean squared error that is often used for determination of accuracy of a mathematical model in the field of meteorology or demography. The quality of the identified parameters is, however, determined not only by right choice of an objective function but also by the source experimental data. One of the possible way is to use load-displacement curves from three-point bending tests that were performed on concrete specimens. This option shows the significance of modulus of elasticity, tensile strength and specific fracture energy. Another possible option is to use experimental data from compact tension test. It is clear that the response in the second type of test is also dependent on the above mentioned material parameters. The question is whether the parameters identified within three-point bending test and within compact tension test will reach the same values. The presented article brings the numerical study of inverse identification of material model parameters from experimental data measured during compact tension tests. The article also presents utilization of the modified sensitivity analysis that calculates the sensitivity of the material model parameters for different parts of loading curve. The main goal of the article is to describe the process of inverse identification of parameters for plasticity-based material model of concrete and prepare data for future comparison with identified values of the material model parameters from different type of fracture tests.

  1. Comment and Completion: Implementation of Parallelism Testing for Four-Parameter Logistic Model in Bioassays.

    Science.gov (United States)

    Sondag, Perceval; Joie, Raphael; Yang, Harry

    2015-01-01

    Parallelism testing between two four-parameter logistic curves has been widely discussed over the last decade. Current tests available in common statistical software used in laboratories have been shown to be highly flawed. In 2012, Yang et al. showed an easy way to implement an intersection union test based on confidence intervals on ratios of parameters of both curves. The method was automated using a fully good manufacturing practice-compliant software package. Although the rationale is correct and efficient, a small mistake appears in the computation of the confidence intervals in the paper and may lead to error when implementing the intersection union test in a software package. Because parallelism testing is both a prerequisite for the determination of relative potency of bioassays and a regulatory requirement, it is important to rectify this mistake. In this paper, we show the actual formulas to be used to compute confidence interval on ratios of parameters. © PDA, Inc. 2015.

  2. Estimation of genetic parameters of test day fat and protein yields in ...

    African Journals Online (AJOL)

    This study was aimed to estimate variance components and genetic parameters for daily fat and protein yields of Brazilian Holstein cattle, using an autoregressive test day multiple lactations (AR) animal model. Data consisted of test day (TD) records produced by Holstein cows under milk recording supervised by the ...

  3. CATS Deliverable 2.2 : CATS car-to-cyclist accident parameters and test scenarios

    NARCIS (Netherlands)

    Uittenbogaard, J.; Camp, O.M.G.C. op den; Montfort, S. van

    2016-01-01

    This report summarizes the work conducted within work package (WP) 2 "Test scenario definition" of the CATS project. It describes relevant accident parameters for the 5 most dominant accidents scenarios defined in WP1. The objective of this WP2 is to construct car-to-cyclist accident test scenarios

  4. Kinetic parameter determination of roasted and unroasted argan oil oxidation under Rancimat test conditions

    National Research Council Canada - National Science Library

    Zaanoun, I; Gharby, S; Bakass, I; Ait addi, E; Ait ichou, I

    2014-01-01

    ...) under the Rancimat test conditions. The physicochemical parameters of edible and cosmetic argan oil immediately after preparation and after accelerated oxidation test Rancimat at different temperatures 90 °C, 100 °C, 110 °C, 120 °C, 130 °C and 140...

  5. A Powerful Test of the Autoregressive Unit Root Hypothesis Based on a Tuning Parameter Free Statistic

    DEFF Research Database (Denmark)

    Nielsen, Morten Ørregaard

    This paper presents a family of simple nonparametric unit root tests indexed by one parameter, d, and containing Breitung's (2002) test as the special case d = 1. It is shown that (i) each member of the family with d > 0 is consistent, (ii) the asymptotic distribution depends on d, and thus refle...

  6. The optimal parameter for radiation dose in pediatric low dose abdominal CT: cross-sectional dimensions versus body weight

    Energy Technology Data Exchange (ETDEWEB)

    Jung, Yoon Young; Goo, Hyun Woo [Asan Medical Center, University of Ulsan, College of Medicine, Seoul (Korea, Republic of)

    2008-02-15

    To investigate the best parameter between cross-sectional dimensions and body weight in pediatric low dose abdominal CT. One hundred and thirty six children consecutively underwent weight-based abdominal CT. The subjects consisted of group 1 (79 children, weight range 10.0-19.9 kg) and group 2 (57 children, weight range 20.0-39.9 kg). Abdominal cross-sectional dimensions including circumference, area, anteroposterior diameters and transverse diameters were calculated. Image noise (standard deviation of CT density) was measured by placing a region of interest in the posterior segment of the right hepatic lobe on a CT image at the celiac axis. The measured image noise was correlated with the cross-sectional abdominal dimensions and body weight for subjects in each group. In group 1 subjects,area, circumference, transverse diameter, anteroposterior diameter, and body weight showed a significant positive correlation with image noise in descending order({gamma} = 0.63, 0.62, 0.61, 0.51, and 0.49; {rho} < 0.0001). In group 2 subjects, transverse diameter, circumference, area, anteroposterior diameter, and body weight showed a significant positive correlation with image noise in descending order ({gamma} = 0.83, 0.82, 0.78, 0.71, and 0.71; {rho} < 0.0001). Cross-sectional dimensions such as area, circumference, and transverse diameter showed a higher positive correlation with image noise than body weight for pediatric low dose abdominal CT.

  7. A Test-Bench for Measurement of Electrical Static Parameters of Strip Silicon Detectors

    CERN Document Server

    Golutvin, I A; Danilevich, V G; Dmitriev, A Yu; Elsha, V V; Zamiatin, Y I; Zubarev, E V; Ziaziulia, F E; Kozus, V I; Lomako, V M; Stepankov, D V; Khomich, A P; Shumeiko, N M; Cheremuhin, A E

    2003-01-01

    An automated test-bench for electrical parameters input control of the strip silicon detectors, used in the End-Cap Preshower detector of the CMS experiment, is described. The test-bench application allows one to solve a problem of silicon detectors input control in conditions of mass production - 1800 detectors over 2 years. The test-bench software is realized in Delphi environment and contains a user-friendly operator interface for measurement data processing and visualization as well as up-to-date facilities for MS-Windows used for the network database. High operating characteristics and reliability of the test-bench were confirmed while more than 800 detectors were tested. Some technical solutions applied to the test-bench could be useful for design and construction of automated facilities for electrical parameters measurements of the microstrip detectors input control.

  8. An Investigation of Proposed Revisions to Section 3 of the TOEFL Test. TOEFL Research Report 47.

    Science.gov (United States)

    Schedl, Mary; And Others

    The Test of English as a Foreign Language (TOEFL) program is exploring a change in Section 3 of the TOEFL test that would replace the vocabulary subpart with additional reading comprehension questions. This study investigated the proposed revision in terms of the length and timing that would be necessary to address concerns of test speededness of…

  9. Methods for Quantifying the Uncertainties of LSIT Test Parameters, Test Results, and Full-Scale Mixing Performance Using Models Developed from Scaled Test Data

    Energy Technology Data Exchange (ETDEWEB)

    Piepel, Gregory F. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Cooley, Scott K. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Kuhn, William L. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Rector, David R. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Heredia-Langner, Alejandro [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2015-05-01

    This report discusses the statistical methods for quantifying uncertainties in 1) test responses and other parameters in the Large Scale Integrated Testing (LSIT), and 2) estimates of coefficients and predictions of mixing performance from models that relate test responses to test parameters. Testing at a larger scale has been committed to by Bechtel National, Inc. and the U.S. Department of Energy (DOE) to “address uncertainties and increase confidence in the projected, full-scale mixing performance and operations” in the Waste Treatment and Immobilization Plant (WTP).

  10. Determination of a quantitative parameter to evaluate swimming technique based on the maximal tethered swimming test.

    Science.gov (United States)

    Soncin, Rafael; Mezêncio, Bruno; Ferreira, Jacielle Carolina; Rodrigues, Sara Andrade; Huebner, Rudolf; Serrão, Julio Cerca; Szmuchrowski, Leszek

    2017-06-01

    The aim of this study was to propose a new force parameter, associated with swimmers' technique and performance. Twelve swimmers performed five repetitions of 25 m sprint crawl and a tethered swimming test with maximal effort. The parameters calculated were: the mean swimming velocity for crawl sprint, the mean propulsive force of the tethered swimming test as well as an oscillation parameter calculated from force fluctuation. The oscillation parameter evaluates the force variation around the mean force during the tethered test as a measure of swimming technique. Two parameters showed significant correlations with swimming velocity: the mean force during the tethered swimming (r = 0.85) and the product of the mean force square root and the oscillation (r = 0.86). However, the intercept coefficient was significantly different from zero only for the mean force, suggesting that although the correlation coefficient of the parameters was similar, part of the mean velocity magnitude that was not associated with the mean force was associated with the product of the mean force square root and the oscillation. Thus, force fluctuation during tethered swimming can be used as a quantitative index of swimmers' technique.

  11. Test techniques: A survey paper on cryogenic tunnels, adaptive wall test sections, and magnetic suspension and balance systems

    Science.gov (United States)

    Kilgore, Robert A.; Dress, David A.; Wolf, Stephen W. D.; Britcher, Colin P.

    1989-01-01

    The ability to get good experimental data in wind tunnels is often compromised by things seemingly beyond our control. Inadequate Reynolds number, wall interference, and support interference are three of the major problems in wind tunnel testing. Techniques for solving these problems are available. Cryogenic wind tunnels solve the problem of low Reynolds number. Adaptive wall test sections can go a long way toward eliminating wall interference. A magnetic suspension and balance system (MSBS) completely eliminates support interference. Cryogenic tunnels, adaptive wall test sections, and MSBS are surveyed. A brief historical overview is given and the present state of development and application in each area is described.

  12. Relationship between anaerobic parameters provided from MAOD and critical power model in specific table tennis test.

    Science.gov (United States)

    Zagatto, A M; Gobatto, C A

    2012-08-01

    The aim of this study was to verify the validity of the curvature constant parameter (W'), calculated from 2-parameter mathematical equations of critical power model, in estimating the anaerobic capacity and anaerobic work capacity from a table tennis-specific test. Specifically, we aimed to i) compare constants estimated from three critical intensity models in a table tennis-specific test (Cf); ii) correlate each estimated W' with the maximal accumulated oxygen deficit (MAOD); iii) correlate each W' with the total amount of anaerobic work (W ANAER) performed in each exercise bout performed during the Cf test. Nine national-standard male table tennis players participated in the study. MAOD was 63.0(10.8) mL · kg - 1 and W' values were 32.8(6.6) balls for the linear-frequency model, 38.3(6.9) balls for linear-total balls model, 48.7(8.9) balls for Nonlinear-2 parameter model. Estimated W' from the Nonlinear 2-parameter model was significantly different from W' from the other 2 models (P0.13). Thus, W' estimated from the 2-parameter mathematical equations did not correlate with MAOD or W ANAER in table tennis-specific tests, indicating that W' may not provide a strong and valid estimation of anaerobic capacity and anaerobic capacity work. © Georg Thieme Verlag KG Stuttgart · New York.

  13. 16 CFR 1611.37 - Reasonable and representative tests under section 8 of the Act.

    Science.gov (United States)

    2010-01-01

    ... guaranteed was manufactured or from whom it was received, to the effect that reasonable and representative..., nap, or tufted construction, tests shall be conducted according to paragraph (b) of this section on...

  14. Wind tunnel testing of a full scale helicopter blade section with an upstream active Gurney flap

    NARCIS (Netherlands)

    Loendersloot, Richard; Freire Gomez, J.; Booker, J.D.

    2014-01-01

    Wind tunnel tests were performed on an aerofoil section comparable to that of a full scale helicopter blade section with an upstream active Gurney flap in the framework of the European project CleanSky ITD Green RotorCraft. A modified NACA0012 profile was used, with 23 Kulite pressure transducers

  15. 76 FR 39110 - Medicare Program; Section 3113: The Treatment of Certain Complex Diagnostic Laboratory Tests...

    Science.gov (United States)

    2011-07-05

    ... classified (NOC)'' code but that would otherwise meet the criteria set forth in section 3113 for being a... Procedure Coding System (HCPCS) code other than a not otherwise classified (NOC) code under such Coding... for diagnostic laboratory tests defined in section 3113(a)(2) but currently billed using NOC codes...

  16. The effects of isolated single umbilical artery on first and second trimester aneuploidy screening test parameters.

    Science.gov (United States)

    Tulek, Firat; Kahraman, Alper; Taskin, Salih; Ozkavukcu, Esra; Soylemez, Feride

    2015-04-01

    Reliability of first and second trimester screening tests largely depends on accurate estimation of maternal serum marker values. Reduced reliability could lead redundant invasive tests or misdiagnosis. Adjustments of serum marker values for confounding factors like insulin-dependent diabetes, maternal weight or maternal rhesus status are essential. We aimed to investigate whether isolated single umbilical artery alters first and second trimester test parameters or not. Routine detailed obstetric ultrasonographies performed were retrospectively screened for this study. Among spontaneously conceived singleton pregnancies, women who were found to have single umbilical artery without any additional structural anomalies or aneuploidies were selected. First and second trimester screening test results were accessible for 98 and 102 of the cases with isolated single umbilical artery, respectively. Among first trimester screening test parameters, PAPP-A (pregnancy-associated plasma protein A) MoMs were found significantly higher in isolated single umbilical artery group. AFP MoMs were found significantly elevated in isolated single umbilical artery group in second trimester quadruple tests. Existence of single umbilical artery could alter the estimation of MoM values of maternal serum markers. Reliability of prenatal screening tests could be improved by adjusting these parameters in accordance with isolated single umbilical artery.

  17. Equivalence testing for parallelism in the four-parameter logistic model.

    Science.gov (United States)

    Jonkman, Jeffrey N; Sidik, Kurex

    2009-09-01

    For assay or dose-response data in drug discovery, it is often important to test for parallelism of the response curves for two preparations, such as a test drug and a standard drug, in order to determine the potency of the test preparation relative to the standard preparation. A typical approach is to perform a three-degree of freedom approximate F test of the null hypothesis that the relevant parameters are equal for the two preparations. We argue that this problem may be more appropriately viewed as a practical equivalence testing problem, and present an alternative method for testing parallelism in the four-parameter logistic response curve, based on the theory of intersection-union tests. The approach is intuitively appealing and simple to implement using commonly available software, and may provide more appropriate inference for the problem of interest. Two examples are discussed to illustrate the testing approach outlined in this article, and to compare it with the typical approach to testing parallelism. A simulation study is also presented to compare the empirical properties of the two different testing approaches for a set of cases based approximately on one of the examples.

  18. Integral test on activation cross section of tag gas nuclides using fast neutron spectrum fields

    Energy Technology Data Exchange (ETDEWEB)

    Aoyama, Takafumi; Suzuki, Soju [Power Reactor and Nuclear Fuel Development Corp., Oarai, Ibaraki (Japan). Oarai Engineering Center

    1997-03-01

    Activation cross sections of tag gas nuclides, which will be used for the failed fuel detection and location in FBR plants, were evaluated by the irradiation tests in the fast neutron spectrum fields in JOYO and YAYOI. The comparison of their measured radioactivities and the calculated values using the JENDL-3.2 cross section set showed that the C/E values ranged from 0.8 to 2.8 for the calibration tests in YAYOI and that the present accuracies of these cross sections were confirmed. (author)

  19. New Tools to Prepare ACE Cross-section Files for MCNP Analytic Test Problems

    Energy Technology Data Exchange (ETDEWEB)

    Brown, Forrest B. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States). Monte Carlo Codes Group

    2016-06-17

    Monte Carlo calculations using one-group cross sections, multigroup cross sections, or simple continuous energy cross sections are often used to: (1) verify production codes against known analytical solutions, (2) verify new methods and algorithms that do not involve detailed collision physics, (3) compare Monte Carlo calculation methods with deterministic methods, and (4) teach fundamentals to students. In this work we describe 2 new tools for preparing the ACE cross-section files to be used by MCNP® for these analytic test problems, simple_ace.pl and simple_ace_mg.pl.

  20. Determination of aquifer parameters using geoelectrical sounding and pumping test data in Khanewal District, Pakistan

    Directory of Open Access Journals (Sweden)

    Akhter Gulraiz

    2016-01-01

    Full Text Available In order to determine the groundwater resources and potentials of the Khanewal District of Pakistan, a geophysical method in combination with pumping test data were used. An analytical relationship between the aquifer parameters interpreted from surface geoelectrical method and pumping test was established in order to estimate aquifer parameters from surface measurements where no pumping tests exist. For the said purpose, 48 geoelectric investigations were carried out using Schlumberger vertical electrical sounding (VES. Seven of the soundings were conducted where pumping tests had been carried out at borehole sites. The vertical electrical sounding stations were interpreted, and resistivities and thickness parameters were calculated. The values of transmissivity and hydraulic conductivity were calculated using the Dar Zarrouk parameter. Transmissivity values obtained from pumping test data and the VES method range between 954 – 4263 m2/day and 200 – 5600 m2/day respectively. Hydraulic conductivity values determined from pumping test data and geoelectrical technique range between 15.9 – 60.9 m/day and 29.76 - 72.3 m/day respectively. The low values of transmissivity and hydraulic conductivity indicate clay or shale while high values are due to the presence of sand or gravel. A comparison of the transmissivity values obtained from pumping test data and surface geoelectrical method shows a positive correlation (R2 =0.90. Similarly, the regression between hydraulic conductivity determined from the pumping test data and the geoelectrical method is also positively correlated (R2 =0.96. The results provide a quick and useful estimation of aquifer properties and potentials.

  1. Determination of aquifer parameters using geoelectrical sounding and pumping test data in Khanewal District, Pakistan

    Science.gov (United States)

    Akhter, Gulraiz; Hasan, M.

    2016-01-01

    In order to determine the groundwater resources and potentials of the Khanewal District of Pakistan, a geophysical method in combination with pumping test data were used. An analytical relationship between the aquifer parameters interpreted from surface geoelectrical method and pumping test was established in order to estimate aquifer parameters from surface measurements where no pumping tests exist. For the said purpose, 48 geoelectric investigations were carried out using Schlumberger vertical electrical sounding (VES). Seven of the soundings were conducted where pumping tests had been carried out at borehole sites. The vertical electrical sounding stations were interpreted, and resistivities and thickness parameters were calculated. The values of transmissivity and hydraulic conductivity were calculated using the Dar Zarrouk parameter. Transmissivity values obtained from pumping test data and the VES method range between 954 - 4263 m2/day and 200 - 5600 m2/day respectively. Hydraulic conductivity values determined from pumping test data and geoelectrical technique range between 15.9 - 60.9 m/day and 29.76 - 72.3 m/day respectively. The low values of transmissivity and hydraulic conductivity indicate clay or shale while high values are due to the presence of sand or gravel. A comparison of the transmissivity values obtained from pumping test data and surface geoelectrical method shows a positive correlation (R2 =0.90). Similarly, the regression between hydraulic conductivity determined from the pumping test data and the geoelectrical method is also positively correlated (R2 =0.96). The results provide a quick and useful estimation of aquifer properties and potentials.

  2. Strategies for estimating the parameters needed for different test-day models.

    Science.gov (United States)

    Misztal, I; Strabel, T; Jamrozik, J; Mäntysaari, E A; Meuwissen, T H

    2000-05-01

    Currently, most analyses of parameters in test-day models involve two types of models: random regression, where various functions describe variability of (co)variances with regard to days in milk, and multiple traits, where observations in adjacent days in milk are treated as one trait. The methodologies used for estimation of parameters included Bayesian via Gibbs sampling, and REML in the form of derivative-free, expectation-maximization, or average-information algorithms. The first method is simpler and uses less memory but may need many rounds to produce posterior samples. In REML, however, the stopping point is well established. Because of computing limitations, the largest estimations of parameters were on fewer than 20,000 animals. The magnitude and pattern of heritabilities varied widely, which could be caused by simplifications in the model, overparameterization, small sample size, and unrepresentative samples. Patterns of heritability differ among random regression and multiple-trait models. Accurate parameters for large multi-trait random regression models may be difficult to obtain at the present time. Parameters that are sufficiently accurate in practice may be obtained outside the complete prediction model by a constructive approach, where parameters averaged over the lactation would be combined with several typical curves for (co)variances for days in milk. Obtained parameters could be used for any model, and could also aid in comparison of models.

  3. Vertical Drop Test of a YS-11 Fuselage Section (Part 2)

    Science.gov (United States)

    Iwasaki, Kazuo; Kumakura, Ikuo; Minegishi, Masakutsu; Shoji, Hirokazu; Yoshimoto, Norio; Miyaki, Hiromitsu; Terada, Hiroyuki; Isoe, Akira; Yamaoka, Toshihiro; Katayama, Noriaki; Hayashi, Toru; Akaso, Tetsuya; Kosaka, Hideyuki

    The Structures and Materials Research Center of the National Aerospace Laboratory of Japan (NAL) and Kawasaki Heavy Industries, Ltd. (KHI) conducted the 2nd vertical drop test of a fuselage section cut from a NAMC YS-11 transport airplane in July 2002. The main objective of this test program was to obtain background data for aircraft cabin safety by drop test of a full-scale fuselage section and to develop computational tool for crash simulation of aircraft fuselage structure. The test article including seats and anthropomorphic test dummies was dropped to a rigid impact surface by free-fall method at a velocity of 7.6m/s (25ft/s). The impact environment and the resultant response of the fuselage structure and the passenger dummies were considered to be severe but potentially survivable. A description of the results of the 1st drop test and the 2nd drop test is presented in this paper.

  4. Detonation wave parameters in a variable cross section channel in gas mixture of methane with oxygen and nitrogen

    Directory of Open Access Journals (Sweden)

    G. Y. Bivol

    2014-01-01

    Full Text Available Propagation of the detonation wave in gas mixtures of methane with oxygen in a channel of variable cross section was studied experimentally. To conduct these investigations a special detonation combustion chamber comprising sections of various diameters has been designed. In the section of detonation wave formation a combustible mixture was ignited. After that, a flame front accelerated till the formation of detonation. At the exit from the combustion chamber there was an outlet conical section. In conducted experiments the toe-in angle was equal to 3 °. The combustion chamber was open-ended. So an initial pressure inside the combustion chamber prior to each experiment was equal to the atmospheric pressure. The initial temperature was ambient one of 300 K. As a diagnostics, piezoelectric sensors of pressure and photo diodes were used.Detonation initiation was accomplished by spark gap. For this pulse generator I-1 was used. Spark energy did not exceed 0.1 J and was much lower than the energy of the direct initiation of detonation.Deflagration-to-detonation transition was occurred. A composition of the mixtures was selected in such a way that the detonation cell width was several times smaller than the diameter of the channel. The mixture was composed by the partial pressures of methane, oxygen, and nitrogen and was kept in the 40 l tank within 24 hours under 5-8 atm. pressure. Возникновение де- тонации возникало вследствие перехода горения в детонацию.The aim of this study was to determine the parameters of a detonation wave in a channel of variable cross section in the methane-oxygen mixture. The influence of nitrogen impurities on the cell size and the speed and pressure of the detonation wave was investigated.The waves velocities and peak pressures at the front of the detonation wave were measured depending on composition, including the presence of nitrogen. The sizes of the

  5. Strategies for estimating the parameters needed for different test-day models

    NARCIS (Netherlands)

    Misztal, I.; Strabel, T.; Jamrozik, J.; Mäntysaari, E.A.; Meuwissen, T.H.E.

    2000-01-01

    Currently, most analyses of parameters in test-day models involve two types of models: random regression, where various functions describe variability of (co)variances with regard to days in milk, and multiple traits, where observations in adjacent days in milk are treated as one trait. The

  6. The Prediction of Item Parameters Based on Classical Test Theory and Latent Trait Theory

    Science.gov (United States)

    Anil, Duygu

    2008-01-01

    In this study, the prediction power of the item characteristics based on the experts' predictions on conditions try-out practices cannot be applied was examined for item characteristics computed depending on classical test theory and two-parameters logistic model of latent trait theory. The study was carried out on 9914 randomly selected students…

  7. Parameter-free testing of the shape of a probability distribution.

    Science.gov (United States)

    Broom, M; Nouvellet, P; Bacon, J P; Waxman, D

    2007-01-01

    The Kolmogorov-Smirnov test determines the consistency of empirical data with a particular probability distribution. Often, parameters in the distribution are unknown, and have to be estimated from the data. In this case, the Kolmogorov-Smirnov test depends on the form of the particular probability distribution under consideration, even when the estimated parameter-values are used within the distribution. In the present work, we address a less specific problem: to determine the consistency of data with a given functional form of a probability distribution (for example the normal distribution), without enquiring into values of unknown parameters in the distribution. For a wide class of distributions, we present a direct method for determining whether empirical data are consistent with a given functional form of the probability distribution. This utilizes a transformation of the data. If the data are from the class of distributions considered here, the transformation leads to an empirical distribution with no unknown parameters, and hence is susceptible to a standard Kolmogorov-Smirnov test. We give some general analytical results for some of the distributions from the class of distributions considered here. The significance level and power of the tests introduced in this work are estimated from simulations. Some biological applications of the method are given.

  8. Placement of Smart Grass reinforcement at test sections Groningen Sea dike

    NARCIS (Netherlands)

    Verhagen, H.J.; van Gerven, K.A.J.; Akkerman, G.J.

    2007-01-01

    The present report deals with the application of a provisional Smart Grass Reinforcement (SGR) system in 2006 for full scale testing of increased overtopping at the Groningen sea dyke test section near Delfzijl, as envisaged in 2007. The SGR has been placed at two strips of 4 m wide: one primary

  9. Mixed Waste Management Facility (MWMF) closure, Savannah River Plant: Clay cap test section construction report

    Energy Technology Data Exchange (ETDEWEB)

    1988-02-26

    This report contains appendices 3 through 6 for the Clay Cap Test Section Construction Report for the Mixed Waste Management Facility (MWMF) closure at the Savannah River Plant. The Clay Cap Test Program was conducted to evaluate the source, lab. permeability, in-situ permeability, and compaction characteristics, representative of kaolin clays from the Aiken, South Carolina vicinity. (KJD)

  10. Evaluation of Dietary Intakes, Body Composition, and Cardiometabolic Parameters in Adolescent Team Sports Elite Athletes: A Cross-sectional Study

    Directory of Open Access Journals (Sweden)

    Javad Hosseinzadeh

    2017-01-01

    Full Text Available Background: Nutritional intake is an important issue in adolescent athletes. Proper athletes' performance is a multifactorial outcome of good training, body composition, and nutritional status. The aim of the present study was to assess nutritional status, body composition, and cardiometabolic factors in adolescent elite athlete's province of Isfahan, Iran. Materials and Methods: In this cross-sectional study, 100 adolescent elite athletes from volleyball, basketball, and soccer teams were selected for the study. Demographic, anthropometric, and cardiometabolic parameters were assessed. Nutritional intakes of participants were recorded using three 24-h recall questioners. Results: Thirty-four female athletes and 66 male athletes participated in this study. Body mass index had not significantly different between the sexes. Energy, protein, carbohydrate, iron, and fat intakes were significantly higher in male athletes (P = 0.02, but calcium and folic acid intakes were not significantly different between the sexes, and Vitamin D intake was significantly higher in females (P = 0.01. Systolic and diastolic blood pressure was significantly higher in males (P = 0.04 and heart rate had not significantly different between the sexes (P = 0.09. Heart murmurs and heart sounds in the majority of participants were normal. Conclusion: All the evaluated anthropometric and cardiometabolic parameters were in normal range in the majority of participants. The results showed that dietary intake in these athletes is approximately normal but micronutrients intake status in these athletes needs to be investigated further and longer.

  11. Evaluation of Dietary Intakes, Body Composition, and Cardiometabolic Parameters in Adolescent Team Sports Elite Athletes: A Cross-sectional Study

    Science.gov (United States)

    Hosseinzadeh, Javad; Maghsoudi, Zahra; Abbasi, Behnood; Daneshvar, Pooya; Hojjati, Atefeh; Ghiasvand, Reza

    2017-01-01

    Background: Nutritional intake is an important issue in adolescent athletes. Proper athletes’ performance is a multifactorial outcome of good training, body composition, and nutritional status. The aim of the present study was to assess nutritional status, body composition, and cardiometabolic factors in adolescent elite athlete's province of Isfahan, Iran. Materials and Methods: In this cross-sectional study, 100 adolescent elite athletes from volleyball, basketball, and soccer teams were selected for the study. Demographic, anthropometric, and cardiometabolic parameters were assessed. Nutritional intakes of participants were recorded using three 24-h recall questioners. Results: Thirty-four female athletes and 66 male athletes participated in this study. Body mass index had not significantly different between the sexes. Energy, protein, carbohydrate, iron, and fat intakes were significantly higher in male athletes (P = 0.02), but calcium and folic acid intakes were not significantly different between the sexes, and Vitamin D intake was significantly higher in females (P = 0.01). Systolic and diastolic blood pressure was significantly higher in males (P = 0.04) and heart rate had not significantly different between the sexes (P = 0.09). Heart murmurs and heart sounds in the majority of participants were normal. Conclusion: All the evaluated anthropometric and cardiometabolic parameters were in normal range in the majority of participants. The results showed that dietary intake in these athletes is approximately normal but micronutrients intake status in these athletes needs to be investigated further and longer. PMID:28904935

  12. Hepatic steatosis in individuals living with HIV measured by controlled attenuation parameter: a cross-sectional study.

    Science.gov (United States)

    Sulyok, Mihály; Makara, Mihály; Rupnik, Zsófia; Ferenci, Tamás; Újhelyi, Eszter; Kormos, Luca; Gerlei, Zsuzsanna; Szlávik, János; Horváth, Gábor; Vályi-Nagy, István

    2015-06-01

    Available data on the prevalence of hepatic steatosis in an unselected HIV-infected population are limited. The aim of this study was to determine the prevalence of hepatic steatosis and assess the associated factors in HIV-infected individuals. One hundred and thirty-six HIV-infected individuals were enrolled in this cross-sectional study. Patients underwent transient elastography and controlled attenuation parameter (CAP) measurements. We analyzed the associations between the CAP value and demographic, metabolic, and immunologic parameters. For the first time, in HIV-infected individuals, we used a continuous scale of CAP values to identify significant covariates of hepatic fat accumulation. As a result and compared with other methods, one of the main advantages of CAP was that the quantitative measurement of liver steatosis could be used for analysis. Using univariate analysis, CAP was significantly correlated with the following continuous variables: CD4 percentage (P=0.035), CD8 percentage (P=0.016), age (PCAP value (P=0.032). Our findings reflect the importance of metabolic factors in hepatic steatosis. The strongest independent covariate was BMI.

  13. A test to assess aerobic and anaerobic parameters during maximal exercise in young girls.

    Science.gov (United States)

    McGawley, Kerry; Leclair, Erwan; Dekerle, Jeanne; Carter, Helen; Williams, Craig A

    2012-05-01

    The Wingate cycle test (WAnT) is a 30-s test commonly used to estimate anaerobic work capacity (AWC). However, the test may be too short to fully deplete anaerobic energy reserves. We hypothesized that a 90-s all-out isokinetic test (ISO_90) would be valid to assess both aerobic and anaerobic capacities in young females. Eight girls (11.9 ± 0.5 y) performed an exhaustive incremental test, a WAnT and an ISO_90. Peak VO2 attained during the ISO_90 was significantly greater than VO2peak. Mean power, end power, fatigue index, total work done and AWC were not significantly different between the WAnT and after 30 s of the 90-s test (i.e., ISO_30). However, 95% limits of agreement showed large variations between the two tests when comparing all anaerobic parameters. It is concluded that an ISO-90 may be a useful test to assess aerobic capacity in young girls. However, since the anaerobic parameters derived from the ISO_30 did not agree with those derived from a traditional WAnT, the validity of using an ISO_90 to assess anaerobic performance and capacity within this population group remains unconfirmed.

  14. Investigation of Operating Pressure Ratio of a Supersonic Wind Tunnel Utilizing Distributed Boundary-layer Suction in Test Section

    Science.gov (United States)

    Cohen, C B; Valerino, A S

    1950-01-01

    Effect of distributed boundary-layer suction on operating pressure ratio of a supersonic wind tunnel was investigated. Investigation was made in 3.84- by 10-inch supersonic tunnel operating at Mach number 2.0 and suction was applied in neighborhood of the normal shock to two walls of a constant-area extension of test section. A reduction of 4 percent of operating pressure ratio was attributed to improved flow conditions at subsonic-diffuser inlet. The theoretical normal shock was, in practice, replaced by a multiple-branch shock configuration across which the flow parameters changed in approximate accordance with the Rankine-Hugoniot values.

  15. Crash Simulation of a Boeing 737 Fuselage Section Vertical Drop Test

    Science.gov (United States)

    Fasanella, Edwin L.; Jackson, Karen E.; Jones, Yvonne T.; Frings, Gary; Vu, Tong

    2004-01-01

    A 30-ft/s vertical drop test of a fuselage section of a Boeing 737 aircraft was conducted in October of 1999 at the FAA Technical Center in Atlantic City, NJ. This test was performed to evaluate the structural integrity of a conformable auxiliary fuel tank mounted beneath the floor and to determine its effect on the impact response of the airframe structure and the occupants. The test data were used to compare with a finite element simulation of the fuselage structure and to gain a better understanding of the impact physics through analytical/experimental correlation. To perform this simulation, a full-scale 3-dimensional finite element model of the fuselage section was developed using the explicit, nonlinear transient-dynamic finite element code, MSC.Dytran. The emphasis of the simulation was to predict the structural deformation and floor-level acceleration responses obtained from the drop test of the B737 fuselage section with the auxiliary fuel tank.

  16. Fracture parameters of concrete after exposure to high temperatures: pilot tests

    Directory of Open Access Journals (Sweden)

    Šimonová Hana

    2017-01-01

    Full Text Available Experimental concrete panels were after an appropriate aging time loaded by high temperatures (550, 600, 800 and 1000 °C in a furnace intended for fire tests of building materials. These panels were heated according to the standard temperature-time curve according to EN 1991-1-2. One of panels was a reference without temperature load. Test specimens were obtained as cores drilled out from panels after performing fire tests. The cylindrical specimens were provided with a central chevron type notch and subsequently tested in three-point bending fracture test. The load versus displacement (deflection in the middle of span diagrams were recorded during testing and basic fracture parameters were subsequently evaluated.

  17. Measurement of cross sections and leptonic forward-backward asymmetries at the Z pole and determination of electroweak parameters

    Energy Technology Data Exchange (ETDEWEB)

    Acciarri, M.; Adam, A.; Adriani, O.; Aguilar-Benitez, M.; Ahlen, S.; Alcaraz, J.; Aloisio, A.; Alverson, G.; Alviggi, M.G.; Ambrosi, G.; An, Q.; Anderhub, H.; Anderson, A.L.; Andreev, V.P.; Angelescu, T.; Antonov, L.; Antreasyan, D.; Alkhazov, G.; Arce, P.; Arefiev, A.; Azemoon, T.; Aziz, T.; Baba, P.V.K.S.; Bagnaia, P.; Bakken, J.A.; Baksay, L.; Ball, R.C.; Banerjee, S.; Banicz, K.; Bao, J.; Barillere, R.; Barone, L.; Baschirotto, A.; Battiston, R.; Bay, A.; Becattini, F.; Becker, U.; Behner, F.; Bencze, G.L.; Berdugo, J.; Berges, P.; Bertucci, B.; Betev, B.L.; Biasini, M.; Biland, A.; Bilei, G.M.; Bizzarri, R.; Blaising, J.J.; Bobbink, G.J.; Bock, R.; Boehm, A.; Borgia, B.; Bourilkov, D.; Bourquin, M.; Boutigny, D.; Bouwens, B.; Brambilla, E.; Branson, J.G.; Brigljevic, V.; Brock, I.C.; Brooks, M.; Bujak, A.; Burger, J.D.; Burger, W.J.; Burgos, C.; Busenitz, J.; Buytenhuijs, A.; Bykov, A.; Cai, X.D.; Capell, M.; Caria, M.; Carlino, G.; Cartacci, A.M.; Casaus, J.; Castello, R.; Cavall; L3 Collaboration

    1994-06-01

    We report on the measurement of the leptonic and hadronic cross sections and leptonic forward-backward asymmetries at the Z peak with the L3 detector at LEP. The total luminosity of 40.8 pb[sup -1] collected in the years 1990, 1991 and 1992 corresponds to 1.09.10[sup 6] hadronic and 0.98.10[sup 5] leptonic Z decays observed. These data allow us to determine the electroweak parameters. From the cross sections we derive the properties of the Z boson: M[sub Z]=91 195[+-]9 MeV, [Gamma][sub Z]=2 494[+-]10 MeV, [Gamma][sub had]=1748[+-]10 MeV, [Gamma][sub l]=83.49[+-]0.46 MeV, assuming lepton universality. We obtain an invisible width of [Gamma][sub inv]=496.5[+-]7.9 MeV which, in the Standard Model, corresponds to a number of light neutrino species of N[sub [nu

  18. Measurements of Cross Sections and Forward-Backward Asymmetries at the Z Resonance and Determination of Electroweak Parameters

    CERN Document Server

    Acciarri, M.; Adriani, O.; Aguilar-Benitez, M.; Alcaraz, J.; Alemanni, G.; Allaby, J.; Aloisio, A.; Alviggi, M.G.; Ambrosi, G.; Anderhub, H.; Andreev, Valery P.; Angelescu, T.; Anselmo, F.; Arefev, A.; Azemoon, T.; Aziz, T.; Bagnaia, P.; Baksay, L.; Balandras, A.; Ball, R.C.; Banerjee, S.; Banerjee, Sw.; Barczyk, A.; Barillere, R.; Barone, L.; Bartalini, P.; Basile, M.; Battiston, R.; Bay, A.; Becattini, F.; Becker, U.; Behner, F.; Bellucci, L.; Berdugo, J.; Berges, P.; Bertucci, B.; Betev, B.L.; Bhattacharya, S.; Biasini, M.; Biland, A.; Blaising, J.J.; Blyth, S.C.; Bobbink, G.J.; Bohm, A.; Boldizsar, L.; Borgia, B.; Bourilkov, D.; Bourquin, M.; Braccini, S.; Branson, J.G.; Brigljevic, V.; Brochu, F.; Brock, I.C.; Buffini, A.; Buijs, A.; Burger, J.D.; Burger, W.J.; Button, A.; Cai, X.D.; Campanelli, Mario; Capell, M.; Cara Romeo, G.; Carlino, G.; Cartacci, A.M.; Casaus, J.; Castellini, G.; Cavallari, F.; Cavallo, N.; Cecchi, C.; Cerrada, M.; Cesaroni, F.; Chamizo, M.; Chang, Y.H.; Chaturvedi, U.K.; Chemarin, M.; Chen, A.; Chen, G.; Chen, G.M.; Chen, H.F.; Chen, H.S.; Chiefari, G.; Cifarelli, L.; Cindolo, F.; Civinini, C.; Clare, I.; Clare, R.; Coignet, G.; Colijn, A.P.; Colino, N.; Costantini, S.; Cotorobai, F.; Cozzoni, B.; de la Cruz, B.; Csilling, A.; Cucciarelli, S.; Dai, T.S.; van Dalen, J.A.; D'Alessandro, R.; de Asmundis, R.; Deglon, P.; Degre, A.; Deiters, K.; della Volpe, D.; Denes, P.; De Notaristefani, F.; De Salvo, A.; Diemoz, M.; van Dierendonck, D.; Di Lodovico, F.; Dionisi, C.; Dittmar, M.; Dominguez, A.; Doria, A.; Dova, M.T.; Duchesneau, D.; Dufournaud, D.; Duinker, P.; Duran, I.; Dutta, S.; El Mamouni, H.; Engler, A.; Eppling, F.J.; Erne, F.C.; Extermann, P.; Fabre, M.; Faccini, R.; Falagan, M.A.; Falciano, S.; Favara, A.; Fay, J.; Fedin, O.; Felcini, M.; Ferguson, T.; Ferroni, F.; Fesefeldt, H.; Fiandrini, E.; Field, J.H.; Filthaut, F.; Fisher, P.H.; Fisk, I.; Forconi, G.; Fredj, L.; Freudenreich, K.; Furetta, C.; Galaktionov, Iouri; Ganguli, S.N.; Garcia-Abia, Pablo; Gataullin, M.; Gau, S.S.; Gentile, S.; Gheordanescu, N.; Giagu, S.; Gong, Z.F.; Grenier, Gerald Jean; Grimm, O.; Gruenewald, M.W.; Guida, M.; van Gulik, R.; Gupta, V.K.; Gurtu, A.; Gutay, L.J.; Haas, D.; Hasan, A.; Hatzifotiadou, D.; Hebbeker, T.; Herve, Alain; Hidas, P.; Hirschfelder, J.; Hofer, H.; Holzner, G.; Hoorani, H.; Hou, S.R.; Iashvili, I.; Innocente, V.; Jin, B.N.; Jones, Lawrence W.; de Jong, P.; Josa-Mutuberria, I.; Khan, R.A.; Kaur, M.; Kienzle-Focacci, M.N.; Kim, D.; Kim, J.K.; Kirkby, Jasper; Kiss, D.; Kittel, W.; Klimentov, A.; Konig, A.C.; Koffeman, E.; Kopp, A.; Koutsenko, V.; Kraber, M.; Kraemer, R.W.; Krenz, W.; Kruger, A.; Kuijten, H.; Kunin, A.; Ladron de Guevara, P.; Laktineh, I.; Landi, G.; Lassila-Perini, K.; Lebeau, M.; Lebedev, A.; Lebrun, P.; Lecomte, P.; Lecoq, P.; Le Coultre, P.; Lee, H.J.; Le Goff, J.M.; Leiste, R.; Leonardi, Emanuele; Levtchenko, P.; Li, C.; Likhoded, S.; Lin, C.H.; Lin, W.T.; Linde, F.L.; Lista, L.; Liu, Z.A.; Lohmann, W.; Longo, E.; Lu, Y.S.; Lu, W.; Lubelsmeyer, K.; Luci, C.; Luckey, David; Lugnier, L.; Luminari, L.; Lustermann, W.; Ma, W.G.; Maity, M.; Malgeri, L.; Malinin, A.; Mana, C.; Mangeol, D.; Marchesini, P.; Marian, G.; Martin, J.P.; Marzano, F.; Massaro, G.G.G.; Mazumdar, K.; McNeil, R.R.; Mele, S.; Merola, L.; Merk, M.; Meschini, M.; Metzger, W.J.; von der Mey, M.; Mihul, A.; Milcent, H.; Mirabelli, G.; Mnich, J.; Mohanty, G.B.; Molnar, P.; Monteleoni, B.; Moulik, T.; Muanza, G.S.; Muheim, F.; Muijs, A.J.M.; Musy, M.; Napolitano, M.; Nessi-Tedaldi, F.; Newman, H.; Niessen, T.; Nisati, A.; Kluge, Hannelies; Organtini, G.; Oulianov, A.; Palomares, C.; Pandoulas, D.; Paoletti, S.; Paoloni, A.; Paolucci, P.; Paramatti, R.; Park, H.K.; Park, I.H.; Pascale, G.; Passaleva, G.; Patricelli, S.; Paul, Thomas Cantzon; Pauluzzi, M.; Paus, C.; Pauss, F.; Peach, D.; Pedace, M.; Pensotti, S.; Perret-Gallix, D.; Petersen, B.; Piccolo, D.; Pierella, F.; Pieri, M.; Piroue, P.A.; Pistolesi, E.; Plyaskin, V.; Pohl, M.; Pojidaev, V.; Postema, H.; Pothier, J.; Produit, N.; Prokofev, D.O.; Prokofev, D.; Quartieri, J.; Rahal-Callot, G.; Rahaman, M.A.; Raics, P.; Raja, N.; Ramelli, R.; Rancoita, P.G.; Raspereza, A.; Raven, G.; Razis, P.; Ren, D.; Rescigno, M.; Reucroft, S.; van Rhee, T.; Riemann, S.; Riles, Keith; Robohm, A.; Rodin, J.; Roe, B.P.; Romero, L.; Rosca, A.; Rosier-Lees, S.; Roth, Stefan; Rubio, J.A.; Ruschmeier, D.; Rykaczewski, H.; Saremi, S.; Sarkar, S.; Salicio, J.; Sanchez, E.; Sanders, M.P.; Sarakinos, M.E.; Schafer, C.; Schegelsky, V.; Schmidt-Kaerst, S.; Schmitz, D.; Schopper, H.; Schotanus, D.J.; Schwering, G.; Sciacca, C.; Sciarrino, D.; Seganti, A.; Servoli, L.; Shevchenko, S.; Shivarov, N.; Shoutko, V.; Shumilov, E.; Shvorob, A.; Siedenburg, T.; Son, D.; Smith, B.; Spillantini, P.; Steuer, M.; Stickland, D.P.; Stone, A.; Stone, H.; Stoyanov, B.; Straessner, A.; Sudhakar, K.; Sultanov, G.; Sun, L.Z.; Suter, H.; Swain, J.D.; Szillasi, Z.; Sztaricskai, T.; Tang, X.W.; Tauscher, L.; Taylor, L.; Tellili, B.; Timmermans, Charles; Ting, Samuel C.C.; Ting, S.M.; Tonwar, S.C.; Toth, J.; Tully, C.; Tung, K.L.; Uchida, Y.; Ulbricht, J.; Uwer, U.; Valente, E.; Vesztergombi, G.; Vetlitsky, I.; Vicinanza, D.; Viertel, G.; Villa, S.; Vivargent, M.; Vlachos, S.; Vodopianov, I.; Vogel, H.; Vogt, H.; Vorobev, I.; Vorobov, A.A.; Vorvolakos, A.; Wadhwa, M.; Wallraff, W.; Wang, M.; Wang, X.L.; Wang, Z.M.; Weber, A.; Weber, M.; Wienemann, P.; Wilkens, H.; Wu, S.X.; Wynhoff, S.; Xia, L.; Xu, Z.Z.; Yang, B.Z.; Yang, C.G.; Yang, H.J.; Yang, M.; Ye, J.B.; Yeh, S.C.; You, J.M.; Zalite, A.; Zalite, Yu.; Zhang, Z.P.; Zhu, G.Y.; Zhu, R.Y.; Zichichi, A.; Zilizi, G.; Zoller, M.

    2000-01-01

    We report on measurements of hadronic and leptonic cross sections and leptonic forward-backward asymmetries performed with the L3 detector in the years $1993-95$.A total luminosity of 103 pb$^{-1}$ was collected at centre-of-mass energies $\\sqrt{s} \\approx m_\\mathrm{Z}$ and $\\sqrt{s} \\approx m_\\mathrm{Z} \\pm 1.8$ GeVwhich corresponds to 2.5 million hadronic and 245 thousand leptonic events selected.These data lead to a significantly improved determination of Z parameters.From the total cross sections, combined with our measurements in $1990-92$,we obtain the final results:%%%\\begin{eqnarr ay*} m_\\mathrm{Z} = 91189.8 \\pm 3.1\\ \\mathrm{MeV} \\, , & & \\Gamma_\\mathrm{Z} = 2502.4 \\pm 4.2\\ \\mathrm{MeV} \\, , \\\\ \\Gamma_\\mathrm{had} = 1741.1 \\pm 3.8\\ \\mathrm{MeV} \\, , & & \\Gamma_\\ell = 84.14 \\pm 0.17\\ \\mathrm{MeV} \\,. \\label{eq:Zpara_abstract}\\end{eqnarray*}%%%An invisible width of $\\Gamma_\\mathrm{inv} = 499.1 \\pm 2.9$ MeV is derived which in the Standard Model yields for the numberof light neutrino spec...

  19. Joint Estimation of Hydraulic and Poroelastic Parameters from a Pumping Test.

    Science.gov (United States)

    Berg, Steven J; Illman, Walter A; Mok, Chin Man W

    2015-01-01

    The coupling of hydraulic and poroelastic processes is critical in predicting processes involving the deformation of the geologic medium in response to fluid extraction or injection. Numerical models that consider the coupling of hydraulic and poroelastic processes require the knowledge of relevant parameters for both aquifer and aquitard units. In this study, we jointly estimated hydraulic and poroelastic parameters from pumping test data exhibiting "reverse water level fluctuations," known as the Noordbergum effect, in aquitards adjacent to a pumped aquifer. The joint estimation was performed by coupling BIOT2, a finite element, two-dimensional, axisymmetric, groundwater model that considers poroelastic effects with the parameter estimation code PEST. We first tested our approach using a synthetic data set with known parameters. Results of the synthetic case showed that for a simple layered system, it was possible to reproduce accurately both the hydraulic and poroelastic properties for each layer. We next applied the approach to pumping test data collected at the North Campus Research Site (NCRS) on the University of Waterloo (UW) campus. Based on the detailed knowledge of stratigraphy, a five-layer system was modeled. Parameter estimation was performed by: (1) matching drawdown data individually from each observation port and (2) matching drawdown data from all ports at a single well simultaneously. The estimated hydraulic parameters were compared to those obtained by other means at the site yielding good agreement. However, the estimated shear modulus was higher than the static shear modulus, but was within the range of dynamic shear modulus reported in the literature, potentially suggesting a loading rate effect. © 2014, National GroundWater Association.

  20. Lexical patterns in the reading comprehension section of the toefl test

    OpenAIRE

    Fabiana Macmillan

    2014-01-01

    The TOEFL (Test of English as a Foreign Language) is currently one of the most widely accepted English language proficiency tests. Designed by the ETS (Educational Testing Service), the main purpose of the TOEFL is to determine whether the English language skills of a student applying to a North American college or university are adequate for enrollment into the selected program of study. This study will focus upon the third section of the TOEFL, Reading Comprehension, which consists of sever...

  1. Cross-sectional, observational study of anterior segment parameters using anterior segment optical coherence tomography in North Indian Population.

    Science.gov (United States)

    Dalal, Latika Khatri; Dhasmana, Renu; Maitreya, Amit

    2017-01-01

    To study the anterior segment (AS) parameters using AS optical coherence tomography (AS-OCT) in the North Indian population. A hospital-based, observational, cross-sectional study was conducted over a period of 1 year. It included 251 normal individuals aged 20-70 years. Participants underwent imaging with AS-OCT.Ocular parameters included anterior chamber angle (ACA), iris cross-sectional area (ICSA), iris thickness (IT), and iris curvature (IC). The parameters were measured nasally and temporally for both sexes and different age groups. The mean age of participants was 48.3 ± 13.9 years and 50.6% were men. The ACA decreased with age whereas ICSA, IT, and IC increased with age. The ACA (P = 0.0001nasally and temporally), ICSA (P = 0.011 nasally, P = 0.027 temporally), IT750 (P = 0.001 nasally, P = 0.011 temporally), IT1500 (P = 0.002 nasally, P = 0.002 temporally), and IC (P = 0.059 nasally, P = 0.128 temporally) underwent statistically significant changes with increasing age. No significant difference was seen in parameters of different sex. In this subset of the Indian population, the change in the AC parameters with age influences the AC dimensions predisposing the eye to glaucomatous conditions. These data are applicable clinically for the assessment and surgical management of patients requiring AS surgery. Objectif: Étudier les paramètres du segment antérieur (AS) en utilisant la tomodensitométrie optique AS (AS-OCT) dans la population du nord de l'Inde. Méthodes: Une étude axée sur l'hôpital, observationnelle et transversale a été menée sur une période de 1 an. Il comprenait 251 individus normaux âgés de 20 à 70 ans. Les participants ont subi une imagerie avec AS-OCT. Les paramètres oculaires comprenaient l'angle de la chambre antérieure (ACA), la surface transversale de l'iris (ICSA), l'épaisseur de l'iris (IT) et la courbure de l'iris (IC). Les paramètres ont été mesurés par voie nasale et temporelle pour les deux sexes et diff

  2. Simulation of Model Force-Loading with Changing Its Position in the Wind Tunnel Test Section

    Directory of Open Access Journals (Sweden)

    V. T. Bui

    2015-01-01

    Full Text Available When planning and implementing an aerodynamic experiment, model sizes and its position in the test section of the wind tunnel (WT play very important role. The paper focuses on the value variations of the aerodynamic characteristics of a model through changing its position in the WT test section and on the attenuation of the velocity field disturbance in front of the model. Flow around aerodynamic model profile in the open test section of the low-speed WT T-500 is simulated at BMSTU Department SM3. The problem is solved in a two-dimensional case using the ANSYS Fluent package. The mathematical model of flow is based on the Reynolds equations closed by the SST turbulence model. The paper also presents the results of the experiment. Experiments conducted in WT T-500 well correlate with the calculated data and show the optimal position in the middle of the test section when conducting the weighing and drainage experiments. Disturbance of tunnel dynamic pressure (velocity head and flow upwash around the model profile and circular cylinder in the WT test section is analyzed. It was found that flow upstream from the front stagnation point on the body weakly depends on the Reynolds number and obtained results can be used to assess the level of disturbances in the flow around a model by incompressible airflow.

  3. THE REGURIMENTS TO THE DIAGNOSTIC PARAMETERS UNDER NONDESTRUCTIVE FATIGUE TESTING OF THE ELEMENTS OF AVIATION STRUCTURES

    Directory of Open Access Journals (Sweden)

    М. Карускевич

    2011-02-01

    Full Text Available The article is devoted to the analysis of physical-mechanical state of constructional materials under cyclic loading. It has been shown that for the estimation of aircraft structures state under scheduled maintenance check intervals, it is necessary to apply the methods with diagnostic parameters, that are continuously alter according to the service life exhausting. The requirements to diagnostic parameters for nondestructive testing of aircraft components have been defined. The deformation relief formed on the surface of alclad alloys  under cyclic loading meets this requirement. It has been shown the ability of application of deformation relief parameters for the estimation of accumulated fatigue damage.

  4. Evaluation of psychosocial and biological parameters in women seeking for a caesarean section and women who are aiming for vaginal delivery: a cross-sectional study.

    Science.gov (United States)

    Tuschy, Benjamin; Berlit, Sebastian; Stützer, Paul; Lis, Stefanie; Schmahl, Christian; Baumgärtner, Ulf; Sütterlin, Marc

    2018-01-17

    To investigate psychosocial and biological parameters that may influence decision-making concerning the mode of delivery in women with caesarean section on maternal request (CSMR). Two hundred and two women were enrolled prospectively. The study sample (n = 93) consisted of women who aimed for CSMR, the control sample were women who seeked for vaginal delivery (n = 109). Parturients of both samples were enrolled during the pre-birth counselling at the delivery room at the University Medical Centre Mannheim, University Heidelberg, Germany. Women completed standardised questionnaires regarding psychosocial burden (SCL-R 90), fear of childbirth (W-DEQ) and anxiety (STAI), personality structure (HEXACO-Pi-R), and ambiguity tolerance (PFI, PNS, and NFC), social support (F-SozU) as well as one questionnaire assessing demographic parameters and further factors potentially influencing their choice of the mode of delivery. Hair cortisol concentration as a marker for chronic psychological stress and pressure pain threshold with a pressure algometer was assessed. Women in the CSMR sample had less social support (F-SozU: 2.99 ± 0.52 vs. 3.12 ± 0.32; p = 0.043) and were less educated (high school or university degree: 37 vs. 71%, p = 0.001) compared to parturients of the control sample. Women who underwent CSMR were less open-minded (HEXACO-Pi-R: 3.08 ± 0.57 vs. 3.26 ± 0.50; p = 0.016) and less extroverted (HEXACO-Pi-R: 3.34 ± 0.36 vs. 3.46 ± 0.41; p = 0.041). The control collective showed higher scores in negative appraisal of the birth ('W-DEQ-negative appraisal': 2.5 ± 0.8 vs. 2.2 ± 0.9; p = 0.006), whereas "lack of positive anticipation" was higher in the study collective ('W-DEQ-lack of positive anticipation': 3.2 ± 1.2 vs. 2.8 ± 0.8; p = 0.015). The study collective had higher pressure pain threshold values (5.07 ± 2.06 vs. 4.35 ± 1.38; p = 0.007), while no significant differences were observed in hair cortisol

  5. Testing for parallelism in the heteroscedastic four-parameter logistic model.

    Science.gov (United States)

    Sidik, Kurex; Jonkman, Jeffrey N

    2016-01-01

    For bioassay data in drug discovery and development, it is often important to test for parallelism of the mean response curves for two preparations, such as a test sample and a reference sample in determining the potency of the test preparation relative to the reference standard. For assessing parallelism under a four-parameter logistic model, tests of the parallelism hypothesis may be conducted based on the equivalence t-test or the traditional F-test. However, bioassay data often have heterogeneous variance across dose levels. Specifically, the variance of the response may be a function of the mean, frequently modeled as a power of the mean. Therefore, in this article we discuss estimation and tests for parallelism under the power variance function. Two examples are considered to illustrate the estimation and testing approaches described. A simulation study is also presented to compare the empirical properties of the tests under the power variance function in comparison to the results from ordinary least squares fits, which ignore the non-constant variance pattern.

  6. Evaluation of Certain Biochemical Parameters of Wrestlers before and after the 20 m Shuttle Run Test

    Science.gov (United States)

    Türkmen, Mehmet

    2017-01-01

    This study was conducted to determine the acute changes after the 20 m shuttle run test in the biochemical parameters and heart rates of wrestlers competing in international competitions on a study population of 21 wrestlers. The mean age of participants was 24.14±2.01 years, mean heights 176±0.06 cm, body weight 76.48±14.76 kg, MaxVO[subscript 2]…

  7. Determination of Constant Parameters of Copper as Power-Law Hardening Material at Different Test Conditions

    OpenAIRE

    Kowser Md. A.; Mahiuddin Md.

    2014-01-01

    In this paper a technique has been developed to determine constant parameters of copper as a power-law hardening material by tensile test approach. A work-hardening process is used to describe the increase of the stress level necessary to continue plastic deformation. A computer program is used to show the variation of the stress-strain relation for different values of stress hardening exponent, n and power-law hardening constant, α . Due to its close tolerances, excellent corrosion resistanc...

  8. The power of testing a semi-parametric shared gamma frailty parameter in failure time data.

    Science.gov (United States)

    Rahgozar, Mehdi; Faghihzadeh, Soghrat; Rouchi, Gholamreza Babaee; Peng, Yingwei

    2008-09-20

    Frailty is usually modeled as an unobserved random variable acting multiplicatively on the baseline hazard function, where a shared unobserved quantity in the intensity induces a positive correlation among the observed failure times. Using the asymptotic properties of the nonparametric maximum likelihood estimator for the gamma frailty model, we derive a power function for testing the shared frailty parameter and evaluate the effect of number of groups and number of individuals per groups on the power of the test by simulation studies. The results show that choosing between 8 and 25 groups with sample sizes between 200 and 500 individuals will be enough to get a high power.

  9. Reduced Postvasectomy Semen Analysis Testing With the Implementation of Special Clearance Parameters.

    Science.gov (United States)

    Bieniek, Jared M; Fleming, Tyler B; Clark, Joseph Y

    2015-09-01

    To determine the applicability of postvasectomy special clearance parameters (semen analysis) suggested by the American Urological Association and to define the associated cost savings with avoidance of further testing. We retrospectively reviewed the cohort of men undergoing vasectomy from December 2009 to August 2012 at a single institution. Patient demographics and postvasectomy semen analysis (PVSA) results were collected for clearance parameter comparisons. During the study period, 230 patients underwent vasectomy with a mean ± SD age of 36.4 ± 6.5 years. Among the cohort, 83.5% were married and 95.2% had one or more children. The initial PVSA was completed by 111 (48.3%) patients at a mean of 17.8 weeks (range 4-45) following vasectomy. Sperm was identified on initial PVSA in 40 patients (36.0%); 1 patient was found to have motile sperm. Of 39 patients, 38 (97.4%) with nonmotile sperm on PVSA could be cleared to cease other contraceptives based on the most recent clearance guidelines. For those completing an initial PVSA, postvasectomy clearance increased from 64.0% to 98.2% representing a potential cost savings of $2356 in repeat semen testing. Postvasectomy contraceptive clearance can be greatly increased when rare nonmotile sperm parameters are included although postvasectomy semen testing compliance remains poor. Copyright © 2015 Elsevier Inc. All rights reserved.

  10. Guidelineness of the parameters using integrated test in down syndrome risk prediction

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Jin Won [Graduate School of Catholic University of Pusan, Busan (Korea, Republic of); Go, Sung Jin; Kang, Se Sik; Kim, Chang Soo [Dept. Radiological Science, College of Health Sciences, Catholic University of Pusan, Busan (Korea, Republic of)

    2016-12-15

    This study was an evaluation of the significance of each parameter through aimed at pregnant women subjected to screening test(integrated test) in predicting risk of Down syndrome. We retrospectively analysed the correlation of risk of Down's syndrome with Nuchal Translucency(NT) images measured by ultrasound, Pregnancy Associated Plasma Protein A(PAPP-A), alpha-fetoprotein(AFP), unconjugated estriol(uE3), human chorionic gonadotrophin(hCG) and Inhibin A by maternal serum. As a result, a significant correlation with NT, uE3, hCG, Inhibin A is revealed with Down's syndrome risk(P<.001). In ROC analysis, AUC of Inhibin A is analysed as the biggest predictor of Down's syndrome(0.859). And the criterion for cut-off was inhibin A 1.4 MoM(sensitivity 81.8%, specificity 75.9%). In conclusion, Inhibin A was the most useful in parameters to predict Down's syndrome in the integrated test. If we make up for the weakness based on the cut-off value of parameters they will be able to be used as an independent indicator in the risk of Down's syndrome screening.

  11. On Parameters Affecting Metal Flow and Friction in the Double Cup Extrusion Test

    DEFF Research Database (Denmark)

    Tan, Xincai; Bay, Niels; Zhang, Wenqi

    1998-01-01

    in numerical simulations often involve strain hardening because friction is expressed as a function of the flow stress or the flow shear stress. The double cup extrusion test is considered to be one of the process tests for determination of friction. In this test, varying heights of the upper and lower cups...... model with constant absolute value excluding the influence of strain hardening on friction was adopted in FEM simulations, in order to more clearly study the individual influence of strain hardening and friction on the metal flow (upper and lower cup height ratio) without interference between the two...... parameters. The predicted results show a good agreement with the experimental data. The influence of material strain hardening. friction and tool geometry on the metal flow in the test has been investigated. By comparisons of the cup height ratio as a function of the punch travel estimated by experiments...

  12. Wall interference tests of a CAST 10-2/DOA 2 airfoil in an adaptive-wall test section

    Science.gov (United States)

    Mineck, Raymond E.

    1987-01-01

    A wind-tunnel investigation of a CAST 10-2/DOA 2 airfoil model has been conducted in the adaptive-wall test section of the Langley 0.3-Meter Transonic Cryogenic Tunnel (TCT) and in the National Aeronautical Establishment High Reynolds Number Two-Dimensional Test Facility. The primary goal of the tests was to assess two different wall-interference correction techniques: adaptive test-section walls and classical analytical corrections. Tests were conducted over a Mach number range from 0.3 to 0.8 and over a chord Reynolds number range from 6 million to 70 million. The airfoil aerodynamic characteristics from the tests in the 0.3-m TCT have been corrected for wall interference by the movement of the adaptive walls. No additional corrections for any residual interference have been applied to the data, to allow comparison with the classically corrected data from the same model in the conventional National Aeronautical Establishment facility. The data are presented graphically in this report as integrated force-and-moment coefficients and chordwise pressure distributions.

  13. Determining the Efficiency of Different Preoperative Difficult Intubation Tests on Patients Undergoing Caesarean Section.

    Science.gov (United States)

    Yıldırım, İlker; İnal, Mehmet Turan; Memiş, Dilek; Turan, F Nesrin

    2017-09-29

    Pregnancy-induced anatomical and physiological changes in the airway make airway management difficult in obstetric patients; thus, preoperative evaluation of the airway is important for obstetric patients. To determine the effectiveness of the modified Mallampati test; the interincisor, sternomental and thyromental distances and the upper limb bite test. The second aim was to assess the effectiveness of the combination of the upper limb bite test with the other tests in obstetric patients. Cross-sectional study. Pregnant women (n=250) scheduled for caesarean section were analysed. The patients' ages, heights and weights were collected. Preoperative airway evaluation was done by using a modified version of the Mallampati test. The interincisor, sternomental and thyromental distances were measured, and the upper limb bite test was performed. The laryngoscopy difficulty was evaluated by using Cormack-Lehane classification. No statistically significant differences were found between groups in age, height or weight (p>0.05). The modified Mallampati test and interincisor, sternomental and thyromental distances revealed a lower number of easy intubations than that determined by the Cormack-Lehane classification and a higher number of difficult intubations than the actual number of cases (p<0.05). The sensitivity and specificity of the modified Mallampati test, the upper limb bite test, the interincisor distance test and the sternomental and thyromental distance tests were found to be 73.08, 57.69, 84.62, 80.77 and 88.46 and 90.62, 99.11, 83.04, 84.37 and 87.05, respectively. When the combinations were examined, the sensitivity and specificity of the combination of the upper limb bite test with the modified Mallampati test were found to be 57.69 and 100, respectively. When the upper limb bite test was combined with the interincisor distance, the sensitivity and specificity were 46.15 and 100, respectively. We found a sensitivity and specificity of 93.75 and 95

  14. Determining the Efficiency of Different Preoperative Difficult Intubation Tests on Patients Undergoing Caesarean Section

    Directory of Open Access Journals (Sweden)

    İlker Yıldırım

    2017-10-01

    Full Text Available Background: Pregnancy-induced anatomical and physiological changes in the airway make airway management difficult in obstetric patients; thus, preoperative evaluation of the airway is important for obstetric patients. Aims: To determine the effectiveness of the modified Mallampati test; the interincisor, sternomental and thyromental distances and the upper limb bite test. The second aim was to assess the effectiveness of the combination of the upper limb bite test with the other tests in obstetric patients. Study Design: Cross-sectional study. Methods: Pregnant women (n=250 scheduled for caesarean section were analysed. The patients" ages, heights and weights were collected. Preoperative airway evaluation was done by using a modified version of the Mallampati test. The interincisor, sternomental and thyromental distances were measured, and the upper limb bite test was performed. The laryngoscopy difficulty was evaluated by using Cormack-Lehane classification. Results: No statistically significant differences were found between groups in age, height or weight (p>0.05. The modified Mallampati test and interincisor, sternomental and thyromental distances revealed a lower number of easy intubations than that determined by the Cormack-Lehane classification and a higher number of difficult intubations than the actual number of cases (p<0.05. The sensitivity and specificity of the modified Mallampati test, the upper limb bite test, the interincisor distance test and the sternomental and thyromental distance tests were found to be 73.08, 57.69, 84.62, 80.77 and 88.46 and 90.62, 99.11, 83.04, 84.37 and 87.05, respectively. When the combinations were examined, the sensitivity and specificity of the combination of the upper limb bite test with the modified Mallampati test were found to be 57.69 and 100, respectively. When the upper limb bite test was combined with the interincisor distance, the sensitivity and specificity were 46.15 and 100, respectively

  15. Measurements of neutron total cross-sections and resonance parameters of erbium at the Pohang Neutron Facility

    Energy Technology Data Exchange (ETDEWEB)

    Wang Taofeng; Lee, Manwoo; Kim, Kyung-Sook [Department of Physics, Kyungpook National University, Daegu 702-701 (Korea, Republic of); Kim, Guinyun, E-mail: gnkim@knu.ac.k [Department of Physics, Kyungpook National University, Daegu 702-701 (Korea, Republic of); Oh, Young Do; Cho, Moo-Hyun; Ko, In Soo; Namkung, Won [Department of Physics, Pohang University of Science and Technology, Pohang 790-784 (Korea, Republic of); Ro, Tae-Ik [Department of Physics, Dong-A University, Busan 604-714 (Korea, Republic of)

    2010-01-15

    We measured neutron total cross-sections of natural erbium in the neutron energy region from 0.2 to 120 eV by using the neutron time-of-flight method at the Pohang Neutron Facility, which consists of an electron linear accelerator, a water-cooled tantalum target with a water moderator, and a 12-m-long time-of-flight path. A {sup 6}Li-ZnS(Ag) scintillator with a diameter of 12.5 cm and a thickness of 1.6 cm was used as a neutron detector, and a group of high-purity natural erbium metallic plates with various thickness was used for the neutron transmission measurements. The present measurement was compared with the existing experimental and the evaluated data. The resonance parameters of {sup 166}Er, {sup 167}Er, {sup 168}Er, and {sup 170}Er in the neutron energy region below 120 eV were extracted from the transmission by using the multilevel R-matrix SAMMY code and were compared with the evaluated data from ENDF/B VII.0 and other previous reported results.

  16. Propriedades psicométricas apresentadas em manuais de testes de inteligência Psychometric parameters in intelligence test directions

    Directory of Open Access Journals (Sweden)

    Ana Paula Porto Noronha

    2003-06-01

    Full Text Available A pesquisa teve como objetivo verificar quais os parâmetros psicométricos apresentados nos manuais de 19 instrumentos de avaliação da inteligência. Os elementos avaliados nos instrumentos foram: análise de itens, padronização, validade e precisão. Os resultados encontrados mostraram que, dos 19 testes avaliados, 89,5% apresentaram estudos de padronização, sendo que o procedimento mais utilizado na escolha dos sujeitos foi o não aleatório (62,2% dos testes. No que se refere à validade, a de construto foi a mais freqüente dentre os testes (94,7%. Observou-se que todos os instrumentos apresentaram verifica��ão da precisão, sendo o método de consistência interna o mais aplicado (78,9%. Conclui-se que, embora os autores concordem que todos os testes devam realizar estudos de verificação dos parâmetros psicométricos e devam possuir normas regionais, tal prática ainda não se encontra totalmente difundida na avaliação psicológica brasileira,This research aimed to verify the psychometric parameters presented in manuals of 19 intelligence tests. The psychometric properties included in the analysis were: item analysis, validity, reliability, and norms studies. The results indicated that 89.5% of the 19 tests presented norming studies. The procedure of sample selection was mostly non-random (62.2% of the tests. Construct validity was the most frequent method used among the studies (94.7%. All tests presented reliability studies, most of them using internal consistency coefficient (78.9%. It is concluded that although the authors agree that all tests need studies to verify psychometric parameters and studies to obtain regional norms this action isn’t divulged totally yet in the Brazilian psychological assessment.

  17. Tracer SWIW tests in propped and un-propped fractures: parameter sensitivity issues, revisited

    Science.gov (United States)

    Ghergut, Julia; Behrens, Horst; Sauter, Martin

    2017-04-01

    Single-well injection-withdrawal (SWIW) or 'push-then-pull' tracer methods appear attractive for a number of reasons: less uncertainty on design and dimensioning, and lower tracer quantities required than for inter-well tests; stronger tracer signals, enabling easier and cheaper metering, and shorter metering duration required, reaching higher tracer mass recovery than in inter-well tests; last not least: no need for a second well. However, SWIW tracer signal inversion faces a major issue: the 'push-then-pull' design weakens the correlation between tracer residence times and georeservoir transport parameters, inducing insensitivity or ambiguity of tracer signal inversion w. r. to some of those georeservoir parameters that are supposed to be the target of tracer tests par excellence: pore velocity, transport-effective porosity, fracture or fissure aperture and spacing or density (where applicable), fluid/solid or fluid/fluid phase interface density. Hydraulic methods cannot measure the transport-effective values of such parameters, because pressure signals correlate neither with fluid motion, nor with material fluxes through (fluid-rock, or fluid-fluid) phase interfaces. The notorious ambiguity impeding parameter inversion from SWIW test signals has nourished several 'modeling attitudes': (i) regard dispersion as the key process encompassing whatever superposition of underlying transport phenomena, and seek a statistical description of flow-path collectives enabling to characterize dispersion independently of any other transport parameter, as proposed by Gouze et al. (2008), with Hansen et al. (2016) offering a comprehensive analysis of the various ways dispersion model assumptions interfere with parameter inversion from SWIW tests; (ii) regard diffusion as the key process, and seek for a large-time, asymptotically advection-independent regime in the measured tracer signals (Haggerty et al. 2001), enabling a dispersion-independent characterization of multiple

  18. Water Impact Test and Simulation of a Composite Energy Absorbing Fuselage Section

    Science.gov (United States)

    Fasanella, Edwin L.; Jackson, Karen E.; Sparks, Chad; Sareen, Ashish

    2003-01-01

    In March 2002, a 25-ft/s vertical drop test of a composite fuselage section was conducted onto water. The purpose of the test was to obtain experimental data characterizing the structural response of the fuselage section during water impact for comparison with two previous drop tests that were performed onto a rigid surface and soft soil. For the drop test, the fuselage section was configured with ten 100-lb. lead masses, five per side, that were attached to seat rails mounted to the floor. The fuselage section was raised to a height of 10-ft. and dropped vertically into a 15-ft. diameter pool filled to a depth of 3.5-ft. with water. Approximately 70 channels of data were collected during the drop test at a 10-kHz sampling rate. The test data were used to validate crash simulations of the water impact that were developed using the nonlinear, explicit transient dynamic codes, MSC.Dytran and LS-DYNA. The fuselage structure was modeled using shell and solid elements with a Lagrangian mesh, and the water was modeled with both Eulerian and Lagrangian techniques. The fluid-structure interactions were executed using the fast general coupling in MSC.Dytran and the Arbitrary Lagrange-Euler (ALE) coupling in LS-DYNA. Additionally, the smooth particle hydrodynamics (SPH) meshless Lagrangian technique was used in LS-DYNA to represent the fluid. The simulation results were correlated with the test data to validate the modeling approach. Additional simulation studies were performed to determine how changes in mesh density, mesh uniformity, fluid viscosity, and failure strain influence the test-analysis correlation.

  19. Determining fracture energy parameters of concrete from the modified compact tension test

    Directory of Open Access Journals (Sweden)

    A. Fernández-Canteli

    2014-10-01

    Full Text Available The modified compact tension (MCT test, though not yet recognized as a valid test for determining fracture energy of concrete, is believed to represent a plausible and suitable alternative versus other well established procedures, such as the wedge-splitting test (WST and the three point (3PB or four point bending (4PB tests, due to its simplicity and low cost. The aim of the paper is twofold: Firstly, to demonstrate the necessary correspondence between the experimental MCT test setup and finite element simulations and secondly, to initiate the way of establishing the desirable conversion between the fracture energy parameter values resulting from the MCT test and the standard conventional procedures. MCT tests are carried out and compared with the numerical results from 2-D and 3-D finite element calculations using the commercial codes ABAQUS and ATENA, the latter being specifically developed for applications on concrete structures and elements. In this way, the usability of the modified compact tension test for practical purposes is confirmed.

  20. Reflection plane tests of a wind turbine blade tip section with ailerons

    Science.gov (United States)

    Savino, J. M.; Nyland, T. W.; Birchenough, A. G.; Jordan, F. L.; Campbell, N. K.

    1985-08-01

    Tests were conducted in the NASA Langley 30 by 60 foot Wind Tunnel on a full scale 7.31 m (24 ft) long tip section of a wind turbine rotor blade. The blade tip section was built with ailerons on the trailing edge. The ailerons, which spanned a length of 6.1 m (20 ft), were designed so that two types could be evaluated: the plain and the balanced. The ailerons were hinged on the suction surface at the 0.62 X chord station behind the leading edge. The purpose of the tests was to measure the aerodynamic characteristics of the blade section for: an angle of attack range from 0 deg to 90 deg aileron deflections from 0 deg to -90 deg, and Reynolds numbers of 0.79 and 1.5 x 10 to the 6th power. These data were then used to determine which aileron configuration had the most desirable rotor control and aerodynamic braking characteristics. Tests were also run to determine the effects of vortex generators, leading edge roughness, and the gaps between the aileron sections on the lift, drag, and chordwise force coefficients of the blade tip section.

  1. Reflection plane tests of a wind turbine blade tip section with ailerons

    Energy Technology Data Exchange (ETDEWEB)

    Savino, J.M.; Nyland, T.W.; Birchenough, A.G.; Jordan, F.L.; Campbell, N.K.

    1985-08-01

    Tests were conducted in the NASA Langley 30- by 60-Foot Wind Tunnel on a full scale 7.31 m (24 ft) long tip section of a wind turbine rotor blade. The blade tip section was built with ailerons on the trailing edge. The ailerons, which spanned a length of 6.1 m (20 ft), were designed so that two types could be evaluated: the plain and the balanced. The ailerons were hinged on the suction surface at the 0.62 X chord station behind the leading edge. The purpose of the tests was to measure the aerodynamic characteristics of the blade section for: an angle-of-attack range from 0/sup 0/ to 90/sup 0/, aileron deflections from 0/sup 0/ to -90/sup 0/, and Reynolds Numbers of 0.79 and 1.5 x 10/sup 6/. These data were then used to determine which aileron configuration had the most desirable rotor control and aerodynamic braking characteristics. Tests were also run to determine the effects of vortex generators, leading edge roughness, and the gaps between the aileron sections on the lift, drag, and chordwise force coefficients of the blade tip section.

  2. A study of relative permeability parameters on rock cores using a two-phase flow test

    Directory of Open Access Journals (Sweden)

    Chung-Hui Chiao

    2017-01-01

    Full Text Available To ensure sequestration safety, confirming the injectivity of the reservoir rock formation is of critical importance, requiring studies of the rock permeability to uncover the fluid migration scenarios within the porous reservoir rock. Two-phase (super-critical CO2-brine flow behavior following the post CO2 injection is believed to be a dominating factor; its flooding behavior within the porous rock media needs to be further clarified prior to confirming the feasibility of domestic CO2 geo-sequestration. This study aims to determine the relative permeability of rock cores obtained from field outcropping. A test facility was established to determine the relative permeability during drainage and imbibition processes using a core-flooding test characterized by displacement method. The test facility was assembled locally and is regarded as a pioneering attempt. By relevant data interpretation, the parameters of relative permeability for predicting the movement of super-critical CO2 after injection can be modeled. More reliable parameters can be obtained using history matching processes wherein time-elapsed data calibration is used in conjunction with a computer code, TOUGH2. The test results were iteratively calibrated using numerical simulation by conducting a history matching process. The K-S curves derived from best-fit parameters are believed to be the most relevant relative permeability for the reservoir rock. Through this preliminary study, a better understanding of some of the problems and limitations associated with the determination of the rock relative permeability using two-phase flow test is achieved, but more advanced research is required.

  3. The cryogenic pumping section of KATRIN and the test experiment TRAP

    CERN Document Server

    Eichelhardt, F

    2011-01-01

    The Karlsruhe Tritium Neutrino experiment (KATRIN) employs a Cryogenic Pumping Section (CPS) at ~ 4.5 K to suppress the tritium penetration into the spectrometers. A test experiment (TRAP - Tritium Argon frost Pump) has been set up to investigate the tritium pumping performance of the CPS.

  4. Calibration of the Flow in the Test Section of the Research Wind Tunnel at DST Group

    Science.gov (United States)

    2015-10-01

    1073. Defence Science and Technology Organisation , Melbourne, Australia. Erm, L. P. 2003 Calibration of the flow in the extended test section...of the low-speed wind tunnel at DSTO. DSTO-TR-1384. Defence Science and Technology Organisation , Melbourne, Australia. Erm, L. P. 2015

  5. Speech-in-noise screening tests by internet, part 3: test sensitivity for uncontrolled parameters in domestic usage.

    Science.gov (United States)

    Leensen, Monique C J; Dreschler, Wouter A

    2013-10-01

    The online speech-in-noise test 'Earcheck' is sensitive for noise-induced hearing loss (NIHL). This study investigates effects of uncontrollable parameters in domestic self-screening, such as presentation level and transducer type, on speech reception thresholds (SRTs) obtained with Earcheck. Subjects performed 26 Earchecks that differed regarding presentation level (65, 71, and 77 dBA), presentation mode (monotic or diotic), and masking noise (two different low-pass filtered noises) in the lab. To investigate effects of test environment, participants conducted eight additional Earchecks at home using different transducer types (headphones or loudspeakers). Thirty noise-exposed workers, either normal-hearing (n = 10), or with different degrees of NIHL (n = 20), participated. There was a minor effect of presentation levels exceeding 65 dBA in severely impaired listeners. Diotic presentation mode yielded lower SRTs compared to monotic presentation mode. Normal-hearing test results at home were poorer than in the laboratory, whereas hearing-impaired subjects performed better in domestic testing. Using loudspeakers deteriorated SRTs significantly in comparison to headphones, but only in hearing-impaired subjects. A monotic presentation mode using headphones is recommended for domestic screening. Since domestic testing affects SRT results, a follow up study using a large study population should assess Earcheck's validity when performed at home.

  6. Experimental Investigation of Tensile Test on Connection of Cold-formed Cut-curved Steel Section

    Science.gov (United States)

    Sani, Mohd Syahrul Hisyam Mohd; Muftah, Fadhluhartini; Rahman, Nurul Farraheeda Abdul; Fakri Muda, Mohd

    2017-08-01

    Cold-formed steel (CFS) is widely used as structural and non-structural components such as roof trusses and purlin. A CFS channel section with double intermediate web stiffener and lipped is chosen based on the broader usage in roof truss construction. CFS section is cut to form cold-formed pre-cut-curved steel section and lastly strengthened by several types of method or likely known as connection to establish the cold-formed cut-curved steel (CFCCS) section. CFCCS is proposed to be used as a top chord section in the roof truss system. The CFCCS is to resist the buckling phenomena of the roof truss structure and reduced the compression effect on the top chord. The tensile test connection of CFCCS section, especially at the flange element with eight types of connection by welding, plate with self-drilling screw and combination is investigated. The flange element is the weakest part that must be solved first other than the web element because they are being cut totally, 100% of their length for curving process. The testing is done using a universal testing machine for a tensile load. From the experiment, specimen with full welding has shown as a good result with an ultimate load of 13.37 kN and reported having 35.41% when compared with normal specimen without any of connection methods. Furthermore, the experimental result is distinguished by using Eurocode 3. The failure of a full welding specimen is due to breaking at the welding location. Additionally, all specimens with either full weld or spot weld or combination failed due to breaking on weld connection, but specimen with flange plate and self-drilling screw failed due to tilting and bearing. Finally, the full welding specimen is chosen as a good connection to perform the strengthening method of CFCCS section.

  7. Experiences in Fabrication and Testing the Prototype of the 4.90 GHz Accelerating Sections for MAMI C

    CERN Document Server

    Jankowiak, A; Schumann, S; Tchoubarov, O

    2004-01-01

    The fourth stage of the Mainz Microtron (MAMI) is under construction as a 855 to 1500 MeV Harmonic Double Sided Microtron[1], with one of its two linacs operating at the MAMI-frequency of 2.45 GHz, the other at 4.90 GHz. The bi-periodic on axis coupled accelerating structure in operation at MAMI has been optimised for 4.90 GHz[2], such a high frequency till now not having been used for high power cw-acceleration. To ensure a smooth and efficient industrial production of the ten 35 AC-sections needed, a prototype was built and high power tested fully in-house at IKPH. After a short recapitulation of the design of the cavity profile, the configuration of the section with its tuners and diagnostic probes is discussed. Details of the procedures of machining, tuning and brazing the resonator discs, and the rf-parameters achieved for the section are given. Finally, the experiences and measurements during its high power test up to 22 kW are reported: the conditioning behaviour and the irreversible permanent as well ...

  8. Drop test and crash simulation of a civil airplane fuselage section

    Directory of Open Access Journals (Sweden)

    Liu Xiaochuan

    2015-04-01

    Full Text Available Crashworthiness of a civil airplane fuselage section was studied in this paper. Firstly, the failure criterion of a rivet was studied by test, showing that the ultimate tension and shear failure loads were obviously affected by the loading speed. The relations between the loading speed and the average ultimate shear, tension loads were expressed by two logarithmic functions. Then, a vertical drop test of a civil airplane fuselage section was conducted with an actual impact velocity of 6.85 m/s, meanwhile the deformation of cabin frame and the accelerations at typical locations were measured. The finite element model of a main fuselage structure was developed and validated by modal test, and the error between the calculated frequencies and the test ones of the first four modes were less than 5%. Numerical simulation of the drop test was performed by using the LS-DYNA code and the simulation results show a good agreement with that of drop test. Deforming mode of the analysis was the same as the drop test; the maximum average rigid acceleration in test was 8.81g while the calculated one was 9.17g, with an error of 4.1%; average maximum test deformation at four points on the front cabin floor was 420 mm, while the calculated one was 406 mm, with an error of 3.2%; the peak value of the calculated acceleration at a typical location was 14.72g, which is lower than the test result by 5.46%; the calculated rebound velocity result was greater than the test result 17.8% and energy absorption duration was longer than the test result by 5.73%.

  9. The design and testing of novel clinical parameters for dose comparison.

    Science.gov (United States)

    Childress, Nathan L; Rosen, Isaac I

    2003-08-01

    New multidimensional dose comparison parameters, normalized agreement test (NAT) values and the NAT index, are introduced and compared with an ideal dose comparison parameter. In this article, we analyze a clinically based two-dimensional (2D) quantitative dose comparison case using a wide range of new and old comparison tools. In doing so, we address the benefits and limitations of many common dose comparison tools. An in-house software program was developed using the MATLAB 6.5 programming language. Using this software, several 2D quantitative dose comparison parameters were calculated for the computed and measured dose distributions in an intensity-modulated radiotherapy (IMRT) prostate cancer treatment. The experiences gained in the design and testing of this software program form the basis of the dose comparison tool analysis. Each dose comparison tool has unique strengths and weaknesses. The underlying assumptions of the NAT values and NAT index lead to acceptable generalized behavior, but are not always valid. A thorough 2D quantitative dose comparison analysis can only be accomplished through the use of many dose comparison tools. The introduction of the NAT index allows a 2D dose comparison to be reduced to a single value, and is thus ideal for setting clinical acceptance criteria for IMRT verifications.

  10. The correlation between GnRH stimulation testing and obstetric ultrasonographic parameters in precocious puberty.

    Science.gov (United States)

    Binay, Cigdem; Simsek, Enver; Bal, Cengiz

    2014-11-01

    The aim of this study was to determine reliable cut-off levels of basal gonadotropin and to assess the correlation of obstetric ultrasound parameters with the GnRH stimulation test. The GnRH stimulation test was performed in a cohort of young female patients who presented at our hospital for the evaluation of early signs of puberty. Using receiver operating curves (ROCs), the sensitivity and specificity of basal luteinising hormone (LH), follicle stimulating hormone (FSH), basal and stimulated LH/FSH ratio, oestradiol levels and ultrasonographic parameters were evaluated at each level, and the area under curve (AUC) was measured. One hundred female children were assessed. We found that LH levels, peak LH/FSH ratio, fundal/cervical ratio, uterus length, and ovarian volume were reliable predictors of central precocious puberty (CPP). Cut-off levels of basal LH and the peak LH/FSH ratio had high specificity in our cohort. In addition, obstetric ultrasound parameters represent reliable predictors for the diagnosis of CPP.

  11. Identification of material parameters for springback prediction using cyclic tension–compression test

    Directory of Open Access Journals (Sweden)

    Thaweesak Phongsai

    2016-10-01

    Full Text Available In sheet metal forming process, springback is a critical problem for die makers, particularly in case of advanced high strength steels. Therefore, FE simulations were often used to calculate materials deformation behavior and the springback occurrence of formed sheet metals. Recently, the Yoshida–Uemori model, a kinematic hardening model, has shown great capability for describing the elastic recovery of a material. Nevertheless, determination of model parameters is sophisticated for industrial applications. In this work, an AHS steel grade JIS JSC780Y was investigated, in which tension–compression tests were carried out and the procedure of parameter identification was analyzed. Different fitting methods were examined and verified by evaluation of cyclic stress–strain responses obtained from simulations of 1–element model and experiments. The most appropriate parameter set was determined. Finally, hat shape forming test was performed and springback obtained by calculation and experiment was compared. It was found that the introduced procedure could be acceptably applied.

  12. Prevalence of food neophobia in pre-school children from southern Poland and its association with eating habits, dietary intake and anthropometric parameters: a cross-sectional study.

    Science.gov (United States)

    Kozioł-Kozakowska, Agnieszka; Piórecka, Beata; Schlegel-Zawadzka, Małgorzata

    2017-12-18

    The present study aimed to assess the prevalence of food neophobia in pre-school children and its association with eating habits, dietary intake and anthropometric parameters. Cross-sectional survey performed in 2012-2013. The Child Food Neophobia Scale (CFNS) adapted by Wardle, Carnell and Cooke was used to assess the level of food neophobia. Dietary intake was measured using an FFQ and dietary records from three days. Anthropometric measurements were taken to determine children's nutritional status and BMI was computed based on Polish growth charts. Wilcoxon's rank test and Pearson's rank-correlation coefficient were applied to compare the level of food neophobia and frequency of consumption of food products and nutrient intakes. Kindergartens in southern Poland located in or near Cracow. Three hundred and twenty-five pre-school children and their parents. Low neophobia was observed in 12·3 % and high neophobia in 10·8 % of the children examined. Children with a high level of neophobia were significantly less likely (Pchildren ate vegetables very rarely, their intakes of vitamin C (36 % of RDA) and thiamin (84 % of RDA) were far below the norms. No differences in anthropometric parameters according to level of food neophobia were observed. High levels of neophobia are associated with diet variation and may enhance the risk of nutritional deficiencies in children.

  13. Optoelectronic measurement system for testing the optical parameters of infrared seeker

    Science.gov (United States)

    He, Wenjun; Liu, Zhiying; Fu, Yuegang

    2018-01-01

    We propose an optoelectronic measurement system for testing the optical parameters of infrared seeker, such as the position of the image plane, the size of the diffused spot, and the diameter of the scanning circle. The measurement method and operating principle of the optoelectronic measurement system have been introduced. The source of the stray light in the optoelectronic measurement system have been analyzed by using FRED software, and the stray light have been restricted effectively by a co-centered mica plate which closes to the substrate of pinhole. Experimental results show that the test error for the size of the diffused spot is less than +/-0.01 mm, the test errors for the position of the image plane and the diameter of the scanning circle are less than +/-0.02 mm.

  14. Sensitivity testing practice on pre-processing parameters in hard and soft coupled modeling

    Directory of Open Access Journals (Sweden)

    Z. Ignaszak

    2010-01-01

    Full Text Available This paper pays attention to the problem of practical applicability of coupled modeling with the use of hard and soft models types and necessity of adapted to that models data base possession. The data base tests results for cylindrical 30 mm diameter casting made of AlSi7Mg alloy were presented. In simulation tests that were applied the Calcosoft system with CAFE (Cellular Automaton Finite Element module. This module which belongs to „multiphysics” models enables structure prediction of complete casting with division of columnar and equiaxed crystals zones of -phase. Sensitivity tests of coupled model on the particular values parameters changing were made. On these basis it was determined the relations of CET (columnar-to-equaiaxed transition zone position influence. The example of virtual structure validation based on real structure with CET zone location and grain size was shown.

  15. Extrahepatic metastasis risk of hepatocellular carcinoma based on α-fetoprotein and tumor staging parameters at cross-sectional imaging

    Directory of Open Access Journals (Sweden)

    Yokoo T

    2017-10-01

    Full Text Available Takeshi Yokoo,1 Amish D Patel,1 Naama Lev-Cohain,1 Amit G Singal,2 Adam C Yopp,3 Ivan Pedrosa1 1Department of Radiology, 2Department of Internal Medicine, 3Department of Surgery, University of Texas Southwestern Medical Center, Dallas, TX, USA Background: Extrahepatic metastases have important implications in the clinical management of hepatocellular carcinoma (HCC. The purpose of this study was to validate tumor staging parameters and serum AFP as risk factors of HCC metastasis.Patients and methods: In this retrospective case–control study, patients with a new diagnosis of HCC (N=236, median age 57 years (range 28–89 years, and male-to-female ratio of 183/53 were divided into a “no-met” group (N=101 without extrahepatic metastasis or a “met” group with extrahepatic metastases (N=135. Metastasis risk factors based on tumor staging parameters (size, number, infiltration, and vascular invasion and serum AFP level were calculated as odds ratio (OR. Sensitivities of the risk factors as metastasis screening tests were also calculated.Results: AFP >400 mg/mL, index tumor size >5 cm, and vascular invasion individually had strong association with metastasis, with OR (95% confidence interval of 11.5 (5.9–22.1, 17.7 (9.0–34.8, and 18.9 (8.2–43.9, respectively, but with moderate sensitivities as metastasis screening tests, with 71.9% (65.7–77.3, 75.6% (69.6–80.7, and 58.5% (52.1–64.7, respectively. Composite multiparametric criteria, eg, a logical union of 1 tumor size outside of Milan criteria, 2 AFP threshold >35 mg/mL, and 3 vascular invasion, had excellent OR up to 55.6 (13.0–237.1 with screening sensitivity 98.5% (95.8–99.6.Conclusion: Serum AFP, tumor size, and vascular invasion are strongly associated with extrahepatic metastasis of HCC, especially when combined into a multiparametric metastasis prediction criterion. Keywords: hepatocellular carcinoma, risk factor, α-fetoprotein, stage, metastasis

  16. Periodontal parameters and BANA test in patients with chronic renal failure undergoing hemodialysis

    Directory of Open Access Journals (Sweden)

    Sérgio Aparecido Torres

    2010-06-01

    Full Text Available OBJECTIVES: The aim of this study was to analyze the periodontal parameters of patients with chronic renal failure. MATERIAL AND METHODS: The periodontal status of 16 Brazilian patients aged 29 to 53 (41.7±7.2 years with chronic renal failure (CRF and another matched group of 14 healthy controls with periodontitis was assessed clinically and microbiologically. Probing pocket depth (PPD, gingival recession (GR, dental plaque index (PLI, gingival index (GI, and dental calculus index (CI were the clinical parameters recorded for the entire dentition (at least 19 teeth, while the anaerobic periodontopathogen colonization in four sites with the highest PPD was evaluated using the BANA test ("PerioScan"; Oral B. RESULTS: The results for the CRF group and control group, respectively were: PPD: 1.77±0.32 and 2.65±0.53; GR: 0.58±0.56 and 0.51±0.36; PLI: 1.64±0.56 and 1.24±0.67; GI: 0.64±0.42 and 0.93±0.50; CI: 1.17±0.54 and 0.87±0.52. Comparison between groups using the "t" test revealed a significantly increased PPD (p<0.001 in the control group. Comparison of the other clincial parameters by the Mann-Whitney test showed differences only for PLI, which was significantly higher (p<0.05 in the CRF group. Spearman's test applied to each group showed a positive correlation among all clinical parameters, except for GR (p<0.05. None of the groups showed any correlation between GR and GI, while a significant negative correlation between GR and PPD was observed for the CRF group. The percentage of BANA-positive sites was 35.9% for the CRF group and 35.7% for the control group. The BANA test correlated positively with PPD only in the control group and with GR only in the CRF group. CONCLUSIONS: In spite of a higher PLI and dense anaerobic microbial population even in shallow PPD, patients with CRF exhibited better periodontal conditions than periodontitis patients, which is an evidence of altered response to local irritants.

  17. Influence of parameter estimation uncertainty in Kriging: Part 2 - Test and case study applications

    Directory of Open Access Journals (Sweden)

    E. Todini

    2001-01-01

    Full Text Available The theoretical approach introduced in Part 1 is applied to a numerical example and to the case of yearly average precipitation estimation over the Veneto Region in Italy. The proposed methodology was used to assess the effects of parameter estimation uncertainty on Kriging estimates and on their estimated error variance. The Maximum Likelihood (ML estimator proposed in Part 1, was applied to the zero mean deviations from yearly average precipitation over the Veneto Region in Italy, obtained after the elimination of a non-linear drift with elevation. Three different semi-variogram models were used, namely the exponential, the Gaussian and the modified spherical, and the relevant biases as well as the increases in variance have been assessed. A numerical example was also conducted to demonstrate how the procedure leads to unbiased estimates of the random functions. One hundred sets of 82 observations were generated by means of the exponential model on the basis of the parameter values identified for the Veneto Region rainfall problem and taken as characterising the true underlining process. The values of parameter and the consequent cross-validation errors, were estimated from each sample. The cross-validation errors were first computed in the classical way and then corrected with the procedure derived in Part 1. Both sets, original and corrected, were then tested, by means of the Likelihood ratio test, against the null hypothesis of deriving from a zero mean process with unknown covariance. The results of the experiment clearly show the effectiveness of the proposed approach. Keywords: yearly rainfall, maximum likelihood, Kriging, parameter estimation uncertainty

  18. Dependence of the source performance on plasma parameters at the BATMAN test facility

    Science.gov (United States)

    Wimmer, C.; Fantz, U.

    2015-04-01

    The investigation of the dependence of the source performance (high jH-, low je) for optimum Cs conditions on the plasma parameters at the BATMAN (Bavarian Test MAchine for Negative hydrogen ions) test facility is desirable in order to find key parameters for the operation of the source as well as to deepen the physical understanding. The most relevant source physics takes place in the extended boundary layer, which is the plasma layer with a thickness of several cm in front of the plasma grid: the production of H-, its transport through the plasma and its extraction, inevitably accompanied by the co-extraction of electrons. Hence, a link of the source performance with the plasma parameters in the extended boundary layer is expected. In order to characterize electron and negative hydrogen ion fluxes in the extended boundary layer, Cavity Ring-Down Spectroscopy and Langmuir probes have been applied for the measurement of the H- density and the determination of the plasma density, the plasma potential and the electron temperature, respectively. The plasma potential is of particular importance as it determines the sheath potential profile at the plasma grid: depending on the plasma grid bias relative to the plasma potential, a transition in the plasma sheath from an electron repelling to an electron attracting sheath takes place, influencing strongly the electron fraction of the bias current and thus the amount of co-extracted electrons. Dependencies of the source performance on the determined plasma parameters are presented for the comparison of two source pressures (0.6 Pa, 0.45 Pa) in hydrogen operation. The higher source pressure of 0.6 Pa is a standard point of operation at BATMAN with external magnets, whereas the lower pressure of 0.45 Pa is closer to the ITER requirements (p ≤ 0.3 Pa).

  19. Dependence of the source performance on plasma parameters at the BATMAN test facility

    Energy Technology Data Exchange (ETDEWEB)

    Wimmer, C.; Fantz, U. [Max-Planck-Institut für Plasmaphysik, Boltzmannstr. 2, 85748 Garching (Germany)

    2015-04-08

    The investigation of the dependence of the source performance (high j{sub H{sup −}}, low j{sub e}) for optimum Cs conditions on the plasma parameters at the BATMAN (Bavarian Test MAchine for Negative hydrogen ions) test facility is desirable in order to find key parameters for the operation of the source as well as to deepen the physical understanding. The most relevant source physics takes place in the extended boundary layer, which is the plasma layer with a thickness of several cm in front of the plasma grid: the production of H{sup −}, its transport through the plasma and its extraction, inevitably accompanied by the co-extraction of electrons. Hence, a link of the source performance with the plasma parameters in the extended boundary layer is expected. In order to characterize electron and negative hydrogen ion fluxes in the extended boundary layer, Cavity Ring-Down Spectroscopy and Langmuir probes have been applied for the measurement of the H{sup −} density and the determination of the plasma density, the plasma potential and the electron temperature, respectively. The plasma potential is of particular importance as it determines the sheath potential profile at the plasma grid: depending on the plasma grid bias relative to the plasma potential, a transition in the plasma sheath from an electron repelling to an electron attracting sheath takes place, influencing strongly the electron fraction of the bias current and thus the amount of co-extracted electrons. Dependencies of the source performance on the determined plasma parameters are presented for the comparison of two source pressures (0.6 Pa, 0.45 Pa) in hydrogen operation. The higher source pressure of 0.6 Pa is a standard point of operation at BATMAN with external magnets, whereas the lower pressure of 0.45 Pa is closer to the ITER requirements (p ≤ 0.3 Pa)

  20. Prolonged storage-induced changes in haematology parameters referred for testing

    Directory of Open Access Journals (Sweden)

    Elise Schapkaitz

    2015-05-01

    Full Text Available Background: Referral of samples for the work-up of haematological disorders from remote laboratories can result in a delay in analysis.Objective: The stability of the full blood count (FBC, differential count (DIFF, reticulocyte and peripheral blood smear (PBS morphology during extended storage was evaluated.Methods: Forty blood samples stored in ethylenediaminetetraacetic acid (EDTA were analysed on an ADVIA® 120 haematology analyser. The samples (25% abnormal; 75% normal were stored at room temperature (RT and at 4 °C – 8 °C. Analysis of samples stored at RT was performed every 12 hours for two days. Analysis of samples stored at 4 °C – 8 °C was performed at 12 hours and subsequently every 24 hours for seven days.Results: FBC parameters (red cell count, haemoglobin and DIFF parameters (percentages of basophils, lymphocytes and monocytes were stable for at least 48 hours when stored at RT. Platelets were only stable for 12 hours and the white cell count was stable for 36 hours when stored at RT. Storing samples at 4 °C – 8 °C significantly increased the stability of most parameters, in particular, mean cell volume and percentage of reticulocytes. However, DIFF parameters were associated with lower stability at 4 °C – 8 °C. PBS morphology was compromised prior to 12 hours whether stored at RT or at 4 °C – 8 °C.Conclusion: This study provides evidence that blood samples stored in EDTA at 4 °C – 8 °C for seven days are suitable for testing on the ADVIA® 120 analyser for the FBC and percentage of reticulocyte parameters. However, storage at 4 °C – 8 °C is not a solution for samples referred for DIFF and PBS morphology review.

  1. A New Parameter to Assess Hydromechanical Effect in Single-hole Hydraulic Testing and Grouting

    Energy Technology Data Exchange (ETDEWEB)

    Rutqvist, Jonny; Fransson, A.; Tsang, C.-F.; Rutqvist, J.; Gustafson, G.

    2007-09-01

    Grouting or filling of the open voids in fractured rock is done by introducing a fluid, a grout, through boreholes under pressure. The grout may be either a Newtonian fluid or a Bingham fluid. The penetration of the grout and the resulting pressure profile may give rise to hydromechanical effects, which depends on factors such as the fracture aperture, pressure at the borehole and the rheological properties of the grout. In this paper, we postulate that a new parameter, {angstrom}, which is the integral of the fluid pressure change in the fracture plane, is an appropriate measure to describe the change in fracture aperture volume due to a change in effective stress. In many cases, analytic expressions are available to calculate pressure profiles for relevant input data and the {angstrom} parameter. The approach is verified against a fully coupled hydromechanical simulator for the case of a Newtonian fluid. Results of the verification exercise show that the new approach is reasonable and that the {angstrom}-parameter is a good measure for the fracture volume change: i.e., the larger the {angstrom}-parameter, the larger the fracture volume change, in an almost linear fashion. To demonstrate the application of the approach, short duration hydraulic tests and constant pressure grouting are studied. Concluded is that using analytic expressions for penetration lengths and pressure profiles to calculate the {angstrom} parameter provides a possibility to describe a complex situation and compare, discuss and weigh the impact of hydromechanical couplings for different alternatives. Further, the analyses identify an effect of high-pressure grouting, where uncontrolled grouting of larger fractures and insufficient (or less-than-expected) sealing of finer fractures is a potential result.

  2. Low hepatitis B testing among migrants: a cross-sectional study in a UK city.

    Science.gov (United States)

    Evlampidou, Iro; Hickman, Matthew; Irish, Charles; Young, Nick; Oliver, Isabel; Gillett, Sophie; Cochrane, Alexandra

    2016-06-01

    In 2012, hepatitis B virus (HBV) testing of people born in a country with a prevalence of ≥2% was recommended in the UK. Implementation of this recommendation requires an understanding of prior HBV testing practice and coverage, for which there are limited data. To estimate the proportion of migrants tested for HBV and explore GP testing practices and barriers to testing. A cross-sectional study of (a) migrants for whom testing was recommended under English national guidance, living in Bristol, and registered with a GP in 2006-2013, and (b) GPs practising in Bristol. NHS patient demographic data and HBV laboratory surveillance data were linked. A person was defined as 'HBV-tested' if a laboratory result was available. An online GP survey was undertaken, using a structured questionnaire. Among 82 561 migrants for whom HBV testing was recommended, 9627 (12%) were 'HBV-tested'. The HBV testing coverage was: Eastern Africa 20%; Western Africa 15%; South Eastern Asia 9%; Eastern Asia 5%. Of 19 GPs, the majority did not use guidelines to inform HBV testing in migrants and did not believe routine testing of migrants was indicated; 12/17 GPs stated that workload and lack of human, and financial resources were the most significant barriers to increased testing. The majority of migrants to a multicultural UK city from medium-/high-prevalence regions have no evidence of HBV testing. Much greater support for primary care in the UK and increased GP awareness of national guidance are required to achieve adherence to current testing guidance. © British Journal of General Practice 2016.

  3. Parameter estimation and statistical test of geographically weighted bivariate Poisson inverse Gaussian regression models

    Science.gov (United States)

    Amalia, Junita; Purhadi, Otok, Bambang Widjanarko

    2017-11-01

    Poisson distribution is a discrete distribution with count data as the random variables and it has one parameter defines both mean and variance. Poisson regression assumes mean and variance should be same (equidispersion). Nonetheless, some case of the count data unsatisfied this assumption because variance exceeds mean (over-dispersion). The ignorance of over-dispersion causes underestimates in standard error. Furthermore, it causes incorrect decision in the statistical test. Previously, paired count data has a correlation and it has bivariate Poisson distribution. If there is over-dispersion, modeling paired count data is not sufficient with simple bivariate Poisson regression. Bivariate Poisson Inverse Gaussian Regression (BPIGR) model is mix Poisson regression for modeling paired count data within over-dispersion. BPIGR model produces a global model for all locations. In another hand, each location has different geographic conditions, social, cultural and economic so that Geographically Weighted Regression (GWR) is needed. The weighting function of each location in GWR generates a different local model. Geographically Weighted Bivariate Poisson Inverse Gaussian Regression (GWBPIGR) model is used to solve over-dispersion and to generate local models. Parameter estimation of GWBPIGR model obtained by Maximum Likelihood Estimation (MLE) method. Meanwhile, hypothesis testing of GWBPIGR model acquired by Maximum Likelihood Ratio Test (MLRT) method.

  4. Development of a Quadrotor Test Bed — Modelling, Parameter Identification, Controller Design and Trajectory Generation

    Directory of Open Access Journals (Sweden)

    Wei Dong

    2015-02-01

    Full Text Available In this paper, a quadrotor test bed is developed. The technical approach for this test bed is firstly proposed by utilizing a commercial quadrotor, a Vicon motion capture system and a ground station. Then, the mathematical model of the quadrotor is formulated considering aerodynamic effects, and the parameter identification approaches for this model are provided accordingly. Based on the developed model and identified parameters, a simulation environment that is consistent with the real system is developed. Subsequently, a flight control strategy and a trajectory generation method, both of which are conceptually and computationally lightweight, are developed and tested in the simulation environment. The developed algorithms are then directly transplanted to the real system, and the experimental results show that their responses in the real-time flights match well with those from the simulations. This indicates that the control algorithms developed for the quadrotor can be preliminarily verified and refined though simulations, and then directly implemented to the real system, which could significantly reduce the experimental risks and costs. Meanwhile, real-time experiments show that the developed flight controller can efficiently stabilize the quadrotor when external disturbances exist, and the trajectory generation approach can provide safe guidance for the quadrotor to fly smoothly through cluttered environments with obstacle rings. All of these features are valuable for real applications, thus demonstrating the feasibility of further development.

  5. Testing for homogeneity in meta-analysis I. The one-parameter case: standardized mean difference.

    Science.gov (United States)

    Kulinskaya, Elena; Dollinger, Michael B; Bjørkestøl, Kirsten

    2011-03-01

    Meta-analysis seeks to combine the results of several experiments in order to improve the accuracy of decisions. It is common to use a test for homogeneity to determine if the results of the several experiments are sufficiently similar to warrant their combination into an overall result. Cochran's Q statistic is frequently used for this homogeneity test. It is often assumed that Q follows a chi-square distribution under the null hypothesis of homogeneity, but it has long been known that this asymptotic distribution for Q is not accurate for moderate sample sizes. Here, we present an expansion for the mean of Q under the null hypothesis that is valid when the effect and the weight for each study depend on a single parameter, but for which neither normality nor independence of the effect and weight estimators is needed. This expansion represents an order O(1/n) correction to the usual chi-square moment in the one-parameter case. We apply the result to the homogeneity test for meta-analyses in which the effects are measured by the standardized mean difference (Cohen's d-statistic). In this situation, we recommend approximating the null distribution of Q by a chi-square distribution with fractional degrees of freedom that are estimated from the data using our expansion for the mean of Q. The resulting homogeneity test is substantially more accurate than the currently used test. We provide a program available at the Paper Information link at the Biometrics website http://www.biometrics.tibs.org for making the necessary calculations. © 2010, The International Biometric Society.

  6. Relationship of kimono grip strength tests with isokinetic parameters in jiu-jitsu athletes

    Directory of Open Access Journals (Sweden)

    Bruno Follmer

    2015-09-01

    Full Text Available DOI: http://dx.doi.org/10.5007/1980-0037.2015v17n5p575   The aim of the present study was to correlate two specific kimono grip strength tests (KGST with elbow flexors and extensors isokinetic parameters in Jiu Jitsu (JJ athletes. Fifteen male JJ athletes, from blue to black belt, participated in the study. The two KGST were: maximum static lift (MSL, and maximum number of repetitions (MNR, both gripping a kimono wrapped around a bar. Isokinetic tests consisted of three sets of 5 s elbow flexion-extension maximum voluntary isometric contraction (MVIC in three different elbow angles (45, 90 and 120°, and two sets of five concentric-eccentric elbow flexion-extension maximum dynamic contractions at 60°·s-1, to determine peak torque (PT. Absolute values of MSL and MNR were 41.4 ± 16.2 s and 10 ± 5 reps, respectively, and tests presented a nearly perfect correlation among them (r=0.91; p<0.001. Significant correlations were reported between MNR and PT during MVIC for elbow flexors at 45° and 90°, elbow extensors at 120°, and during concentric and eccentric dynamic contractions for both flexors and extensors. Therefore, KGST were highly correlated with isokinetic parameters, and were nearly perfect correlated among them, supporting that one of the tests could be chosen to evaluate strength in JJ athletes. The MNR test presented apparently higher levels of relation than MSL, and provided significant information about muscle strength endurance in JJ athletes

  7. Prediction of uterine dehiscence using ultrasonographic parameters of cesarean section scar in the nonpregnant uterus: a prospective observational study

    National Research Council Canada - National Science Library

    Pomorski, Michal; Fuchs, Tomasz; Zimmer, Mariusz

    2014-01-01

    Every year 1.5 million cesarean section procedures are performed worldwide. As many women decide to get pregnant again, the population of pregnant women with a history of cesarean section is growing rapidly...

  8. Implementation of parallelism testing for four-parameter logistic model in bioassays.

    Science.gov (United States)

    Yang, Harry; Kim, Hyun Jun; Zhang, Lanju; Strouse, Robert J; Schenerman, Mark; Jiang, Xu-Rong

    2012-01-01

    Parallelism is a prerequisite for the determination of relative potency in bioactivity assays. It involves the testing of similarity between a pair of dose-response curves of reference standard and test sample. The evaluation of parallelism is a requirement listed by both the United States Pharmacopeia (USP) and European Pharmacopeia (EP). The revised USP Chapters 〈1032〉 and 〈1034〉 suggest testing parallelism using an equivalence method. However, implementation of this method can be challenging for laboratories that lack experience in statistical analysis and software development. In this paper we present a customized assay analysis template that is developed based on a fully good manufacturing practice (GMP)-compliant software package. The template allows for automation of the USP-recommended equivalence parallelism testing method for 4PLmodel in bioassays. It makes the implementation of the USP guidance both practical and feasible. Use of the analysis template is illustrated through a practical example. Parallelism is a prerequisite for the determination of relative potency in bioactivity assays. It involves the testing of similarity between a pair of dose-response curves of reference standard and test sample. The evaluation of parallelism is a requirement listed by both the United States Pharmacopeia (USP) and European Pharmacopeia (EP). The revised USP Chapters 〈1032〉 and 〈1034〉 suggest testing parallelism using an equivalence method. However, implementation of this method can be challenging for laboratories that lack experience in statistical analysis and software development. In this paper we present a customized assay analysis template that is developed based on a fully good manufacturing practice (GMP)-compliant software package. The template allows for automation of the USP-recommended equivalence parallelism testing method for 4-parameter logistic model in bioassays. It makes the implementation of the USP guidance both practical and

  9. Influence of test parameters on the thermal-mechanical fatigue behavior of a superalloy

    Science.gov (United States)

    Malpertu, J. L.; Rémy, L.

    1990-01-01

    The thermal-mechanical fatigue (TMF) behavior of IN-100, a cast nickel-base superalloy, was investigated with a basic mechanical strain-temperature loop applied in a temperature range from 600 °C to 1050 °C (873 to 1323 K). Peak strains were applied at intermediate temperatures, giving a faithful simulation of real component parts. Tests with or without a mean strain were used; other tests involved a longer period or a tensile hold time, and they were compared with conventional “in-phase” TMF cycles. An interrupted test procedure was used with a plastic replication technique to define a conventional TMF life to 0.3-mm crack depth, as well as a life to 50-µm, crack depth, to characterize the crack initiation period. Some stress-strain hysteresis loops were reported. Thermal-mechanical fatigue life was found to be dependent upon test parameters, while the life to crack initiation was not. Oxidation of specimens and micro-cracks was found to be important in all the tests. These results were then discussed and compared with those under low cycle fatigue at high temperature.

  10. [Clinical application of the "Stop walking while talking test". Relationship with geriatric assessment parameters and other tests of balance and gait].

    Science.gov (United States)

    González-Ávila, Bárbara; Roqueta, Cristina; Farriols, Cristina; Álvaro, Margarita; Roig, Alba; Cervera, Anton Maria; Miralles, Ramón

    To assess the relationship between the Stop Walking While Talking (SWWT) test and some parameters of the geriatric assessment, as well as other tests of balance and gait. A prospective, observational and cross-sectional study conducted on 108 patients (62% women), with a mean age of 80.5±8.4 years. Twenty-three of them were living at home, 24 in a nursing home, and 61 in an intermediate care unit. A record was made of the Barthel index, Mini-Mental State Examination of Folstein (MMSE), comorbidity (Charlson index), the presence of previous falls, and fear of falling. Timed Up and Go (TUG), Tinetti test, and Stop Walking While Talking (SWWT) test, were performed on all the patients. Based on the results of the SWWT test patients were divided in two groups: "stoppers" and "non-stoppers". All patients were able to walk (with or without walking aids). The stoppers group of patients had a mean age 82.2±8.7; Barthel index 64.6±20.7; MMSE 21.6±5.1; Charlson index 1.8±1.7, and the non-stoppers 78.5±7.6 (P=.024), 86.0±18.1 (P20seconds, 52 (82.5%) were stoppers and 11 (17.5%) non-stoppers. Of the 31 with TUG between 10-20seconds, 5 (16.1%) were stoppers and 26 (83.9%) non-stoppers. Of the 14 with TUGTinetti test in the stoppers group was 15.4±5.2, and in non-stoppers 23.9±4.6 (PTinetti test, and longer times in the TUG. Copyright © 2016 SEGG. Publicado por Elsevier España, S.L.U. All rights reserved.

  11. Calibration of DEM parameters on shear test experiments using Kriging method

    Science.gov (United States)

    Xavier, Bednarek; Sylvain, Martin; Abibatou, Ndiaye; Véronique, Peres; Olivier, Bonnefoy

    2017-06-01

    Calibration of powder mixing simulation using Discrete-Element-Method is still an issue. Achieving good agreement with experimental results is difficult because time-efficient use of DEM involves strong assumptions. This work presents a methodology to calibrate DEM parameters using Efficient Global Optimization (EGO) algorithm based on Kriging interpolation method. Classical shear test experiments are used as calibration experiments. The calibration is made on two parameters - Young modulus and friction coefficient. The determination of the minimal number of grains that has to be used is a critical step. Simulations of a too small amount of grains would indeed not represent the realistic behavior of powder when using huge amout of grains will be strongly time consuming. The optimization goal is the minimization of the objective function which is the distance between simulated and measured behaviors. The EGO algorithm uses the maximization of the Expected Improvement criterion to find next point that has to be simulated. This stochastic criterion handles with the two interpolations made by the Kriging method : prediction of the objective function and estimation of the error made. It is thus able to quantify the improvement in the minimization that new simulations at specified DEM parameters would lead to.

  12. Testing the hypothesis on the relationship between aerodynamic roughness length and albedo using vegetation structure parameters.

    Science.gov (United States)

    Cho, Jaeil; Miyazaki, Shin; Yeh, Pat J-F; Kim, Wonsik; Kanae, Shinjiro; Oki, Taikan

    2012-03-01

    Surface albedo (α) and aerodynamic roughness length (z(0)), which partition surface net radiation into energy fluxes, are critical land surface properties for biosphere-atmosphere interactions and climate variability. Previous studies suggested that canopy structure parameters influence both α and z(0); however, no field data have been reported to quantify their relationships. Here, we hypothesize that a functional relationship between α and z(0) exists for a vegetated surface, since both land surface parameters can be conceptually related to the characteristics of canopy structure. We test this hypothesis by using the observed data collected from 50 site-years of field measurements from sites worldwide covering various vegetated surfaces. On the basis of these data, a negative linear relationship between α and log(z(0)) was found, which is related to the canopy structural parameter. We believe that our finding is a big step toward the estimation of z(0) with high accuracy. This can be used, for example, in the parameterization of land properties and the observation of z(0) using satellite remote sensing.

  13. The SEGUE Stellar Parameter Pipeline. 1. Description and Initial Validation Tests

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Young Sun; Beers, Timothy C.; Sivarani, Thirupathi; /Michigan State U. /Michigan State U., JINA; Allende Prieto, Carlos; Koesterke, Lars; /Texas U., Astron. Dept.; Wilhelm, Ronald; /Texas Tech.; Norris, John e.; /Res. Sch. Astron. Astrophys., Weston Creek; Bailer-Jones, Coryn A.L.; Re Fiorentin, Paola; /Heidelberg, Max Planck Inst. Astron.; Rockosi, Constance M.; /Lick Observ.; Yanny, Brian; /Fermilab /Rensselaer Poly. /Harvard-Smithsonian Ctr. Astrophys.

    2007-10-01

    The authors describe the development and implementation of the SEGUE (Sloan Extension for Galactic Exploration and Understanding) Stellar Parameter Pipeline (SSPP). The SSPP derives, using multiple techniques, radial velocities and the fundamental stellar atmospheric parameters (effective temperature, surface gravity, and metallicity) for AFGK-type stars, based on medium-resolution spectroscopy and ugriz photometry obtained during the course of the original Sloan Digital Sky Survey (SDSS-I) and its Galactic extension (SDSS-II/SEGUE). the SSPP also provides spectral classification for a much wider range of stars, including stars with temperatures outside of the window where atmospheric parameters can be estimated with the current approaches. This is Paper I in a series of papers on the SSPP; it provides an overview of the SSPP, and initial tests of its performance using multiple data sets. Random and systematic errors are critically examined for the current version of the SSPP, which has been used for the sixth public data release of the SDSS (DR-6).

  14. Calibration of DEM parameters on shear test experiments using Kriging method

    Directory of Open Access Journals (Sweden)

    Bednarek Xavier

    2017-01-01

    Full Text Available Calibration of powder mixing simulation using Discrete-Element-Method is still an issue. Achieving good agreement with experimental results is difficult because time-efficient use of DEM involves strong assumptions. This work presents a methodology to calibrate DEM parameters using Efficient Global Optimization (EGO algorithm based on Kriging interpolation method. Classical shear test experiments are used as calibration experiments. The calibration is made on two parameters - Young modulus and friction coefficient. The determination of the minimal number of grains that has to be used is a critical step. Simulations of a too small amount of grains would indeed not represent the realistic behavior of powder when using huge amout of grains will be strongly time consuming. The optimization goal is the minimization of the objective function which is the distance between simulated and measured behaviors. The EGO algorithm uses the maximization of the Expected Improvement criterion to find next point that has to be simulated. This stochastic criterion handles with the two interpolations made by the Kriging method : prediction of the objective function and estimation of the error made. It is thus able to quantify the improvement in the minimization that new simulations at specified DEM parameters would lead to.

  15. Measurements of Physical Parameters of White Dwarfs: A Test of the Mass-Radius Relation

    Science.gov (United States)

    Bédard, A.; Bergeron, P.; Fontaine, G.

    2017-10-01

    We present a detailed spectroscopic and photometric analysis of 219 DA and DB white dwarfs for which trigonometric parallax measurements are available. Our aim is to compare the physical parameters derived from the spectroscopic and photometric techniques, and then to test the theoretical mass-radius relation for white dwarfs using these results. The agreement between spectroscopic and photometric parameters is found to be excellent, especially for effective temperatures, showing that our model atmospheres and fitting procedures provide an accurate, internally consistent analysis. The values of surface gravity and solid angle obtained, respectively, from spectroscopy and photometry, are combined with parallax measurements in various ways to study the validity of the mass-radius relation from an empirical point of view. After a thorough examination of our results, we find that 73% and 92% of the white dwarfs are consistent within 1σ and 2σ confidence levels, respectively, with the predictions of the mass-radius relation, thus providing strong support to the theory of stellar degeneracy. Our analysis also allows us to identify 15 stars that are better interpreted in terms of unresolved double degenerate binaries. Atmospheric parameters for both components in these binary systems are obtained using a novel approach. We further identify a few white dwarfs that are possibly composed of an iron core rather than a carbon/oxygen core, since they are consistent with Fe-core evolutionary models.

  16. Pendulum test measure correlates with gait parameters in children with cerebral palsy.

    Science.gov (United States)

    Lotfian, M; Mirbagheri, M M; Kharazi, M R; Dadashi, F; Nourian, R; Irani, A; Mirbagheri, A

    2016-08-01

    Individuals with cerebral palsy (CP) usually suffer from different impairments including gait impairment and spasticity. Spastic hypertonia is a defining feature of spasticity and manifests as a mechanical abnormality. The objective of this study was to determine the relationship between spastic hypertonia and gait impairments in spastic children with CP, addressing an important controversial issue. Spastic hypertonia was quantified using the pendulum test. The gait impairments were evaluated using the motion capture system in a gait laboratory. Our results showed significant correlations among gait parameters; i.e. walking speed, step length, and the pendulum test measures. This indicates that neuromuscular abnormalities are associated with spasticity and may contribute to gait impairments. The clinical implication is that the impaired gait in children with CP may be improved with the treatment of neuromuscular abnormalities.

  17. Tests on GFRP Pultruded Profiles with Channel Section Subjected to Web Crippling

    Science.gov (United States)

    Zhang, Wenxue; Chen, Yu

    2017-08-01

    This paper presents an experimental investigation on the web-crippling behavior in glass fibre reinforced polymer (GFRP) pultruded profiles with channel section. A main bending main crack on the web is the main failure mode in the test. The effects of the loading positions, the supporting conditions and bearing lengths on the web crippling behavior of GFRP pultruded profiles with channel section are discussed. Specimens with interior bearing load have higher ultimate strength and all the specimens with loading conditions IG reached the highest ultimate strength but all ruptured. Ultimate strengths of GFRP pultruded profiles with channel section can not be enhanced by increasing the length of the bearing plate. Finite element models were developed to numerically simulate the test results in the terms of ultimate loads, failure modes and load-displacement curves. Based on the results of the parametric study, a number of design formulas are proposed in this paper to accurately predict web crippling ultimate capacity of pultruded GFRP channel sections under four loading and boundary conditions.

  18. The influence of the equivalent hydraulic diameter on the pressure drop prediction of annular test section

    Science.gov (United States)

    Al-Kayiem, A. H. H.; Ibrahim, M. A.

    2015-12-01

    The flow behaviour and the pressure drop throughout an annular flow test section was investigated in order to evaluate and justify the reliability of experimental flow loop for wax deposition studies. The specific objective of the present paper is to assess and highlight the influence of the equivalent diameter method on the analysis of the hydrodynamic behaviour of the flow and the pressure drop throughout the annular test section. The test section has annular shape of 3 m length with three flow passages, namely; outer thermal control jacket, oil annular flow and inner pipe flow of a coolant. The oil annular flow has internal and external diameters of 0.0422 m and 0.0801 m, respectively. Oil was re-circulated in the annular passage while a cold water-glycol mixture was re-circulated in the inner pipe counter currently to the oil flow. The experiments were carried out at oil Reynolds number range of 2000 to 17000, covering laminar, transition and turbulent flow regimes. Four different methods of equivalent diameter of the annulus have been considered in this hydraulic analysis. The correction factor model for frictional pressure drop was also considered in the investigations. All methods addressed the high deviation of the prediction from the experimental data, which justified the need of a suitable pressure prediction correlation for the annular test section. The conventional hydraulic diameter method is a convenient substitute for characterizing physical dimension of a non-circular duct, and it leads to fairly good correlation between turbulent fluid flow and heat transfer characteristic of annular ducts.

  19. Estimation of genetic parameters for test day records of dairy traits in the first three lactations

    Directory of Open Access Journals (Sweden)

    Ducrocq Vincent

    2005-05-01

    Full Text Available Abstract Application of test-day models for the genetic evaluation of dairy populations requires the solution of large mixed model equations. The size of the (covariance matrices required with such models can be reduced through the use of its first eigenvectors. Here, the first two eigenvectors of (covariance matrices estimated for dairy traits in first lactation were used as covariables to jointly estimate genetic parameters of the first three lactations. These eigenvectors appear to be similar across traits and have a biological interpretation, one being related to the level of production and the other to persistency. Furthermore, they explain more than 95% of the total genetic variation. Variances and heritabilities obtained with this model were consistent with previous studies. High correlations were found among production levels in different lactations. Persistency measures were less correlated. Genetic correlations between second and third lactations were close to one, indicating that these can be considered as the same trait. Genetic correlations within lactation were high except between extreme parts of the lactation. This study shows that the use of eigenvectors can reduce the rank of (covariance matrices for the test-day model and can provide consistent genetic parameters.

  20. The effect of sample handling on cross sectional HIV incidence testing results.

    Directory of Open Access Journals (Sweden)

    Oliver Laeyendecker

    Full Text Available To determine if mishandling prior to testing would make a sample from a chronically infected subject appear recently infected when tested by cross-sectional HIV incidence assays.Serum samples from 31 subjects with chronic HIV infection were tested. Samples were subjected to different handling conditions, including incubation at 4 °C, 25 °C and 37 °C, for 1, 3, 7 or 15 days prior to testing. Samples were also subjected to 1,3, 7 and 15 freeze-thaw cycles prior to testing. Samples were tested using the BED capture enzyme immuno assay (BED-CEIA, Vironostika-less sensitive (V-LS, and an avidity assay using the Genetic Systems HIV-1/HIV-2 plus O EIA (avidity assay.Compared to the sample that was not subjected to any mishandling conditions, for the BED-CEIA, V-LS and avidity assay, there was no significant change in test results for samples incubated at 4 °C or 25 °C prior to testing. No impact on test results occurred after 15 freeze-thaw cycles. A decrease in assay results was observed when samples were held for 3 days or longer at 37 °C prior to testing.Samples can be subjected up to 15 freeze-thaw cycles without affecting the results the BED-CEIA, Vironostika-LS, or avidity assays. Storing samples at 4 °C or 25 °C for up to fifteen days prior to testing had no impact on test results. However, storing samples at 37°C for three or more days did affect results obtained with these assays.

  1. Improving clinical cognitive testing: report of the AAN Behavioral Neurology Section Workgroup.

    Science.gov (United States)

    Daffner, Kirk R; Gale, Seth A; Barrett, A M; Boeve, Bradley F; Chatterjee, Anjan; Coslett, H Branch; D'Esposito, Mark; Finney, Glen R; Gitelman, Darren R; Hart, John J; Lerner, Alan J; Meador, Kimford J; Pietras, Alison C; Voeller, Kytja S; Kaufer, Daniel I

    2015-09-08

    To evaluate the evidence basis of single-domain cognitive tests frequently used by behavioral neurologists in an effort to improve the quality of clinical cognitive assessment. Behavioral Neurology Section members of the American Academy of Neurology were surveyed about how they conduct clinical cognitive testing, with a particular focus on the Neurobehavioral Status Exam (NBSE). In contrast to general screening cognitive tests, an NBSE consists of tests of individual cognitive domains (e.g., memory or language) that provide a more comprehensive diagnostic assessment. Workgroups for each of 5 cognitive domains (attention, executive function, memory, language, and spatial cognition) conducted evidence-based reviews of frequently used tests. Reviews focused on suitability for office-based clinical practice, including test administration time, accessibility of normative data, disease populations studied, and availability in the public domain. Demographic and clinical practice data were obtained from 200 respondents who reported using a wide range of cognitive tests. Based on survey data and ancillary information, between 5 and 15 tests in each cognitive domain were reviewed. Within each domain, several tests are highlighted as being well-suited for an NBSE. We identified frequently used single-domain cognitive tests that are suitable for an NBSE to help make informed choices about clinical cognitive assessment. Some frequently used tests have limited normative data or have not been well-studied in common neurologic disorders. Utilizing standardized cognitive tests, particularly those with normative data based on the individual's age and educational level, can enhance the rigor and utility of clinical cognitive assessment. © 2015 American Academy of Neurology.

  2. Multi-parameter fibre Bragg grating sensor-array for thermal vacuum cycling test

    Science.gov (United States)

    Cheng, L.; Ahlers, B.; Toet, P.; Casarosa, G.; Appolloni, M.

    2017-11-01

    Fibre Bragg Grating (FBG) sensor systems based on optical fibres are gaining interest in space applications. Studies on Structural Health Monitoring (SHM) of the reusable launchers using FBG sensors have been carried out in the Future European Space Transportation Investigations Programme (FESTIP). Increasing investment in the development on FBG sensor applications is foreseen for the Future Launchers Preparatory Programme (FLPP). TNO has performed different SHM measurements with FBGs including on the VEGA interstage [1, 2] in 2006. Within the current project, a multi-parameter FBG sensor array demonstrator system for temperature and strain measurements is designed, fabricated and tested under ambient as well as Thermal Vacuum (TV) conditions in a TV chamber of the European Space Agency (ESA), ESTEC site. The aim is the development of a multi-parameters measuring system based on FBG technology for space applications. During the TV tests of a Space Craft (S/C) or its subsystems, thermal measurements, as well as strain measurements are needed by the engineers in order to verify their prediction and to validate their models. Because of the dimensions of the test specimen and the accuracy requested to the measurement, a large number of observation/measuring points are needed. Conventional sensor systems require a complex routing of the cables connecting the sensors to their acquisition unit. This will add extra weight to the construction under test. FBG sensors are potentially light-weight and can easily be multiplexed in an array configuration. The different tasks comply of a demonstrator system design; its component selection, procurement, manufacturing and finally its assembly. The temperature FBG sensor is calibrated in a dedicated laboratory setup down to liquid nitrogen (LN2) temperature at TNO. A temperature-wavelength calibration curve is generated. After a test programme definition a setup in thermal vacuum is realised at ESA premises including a mechanical

  3. Detonation wave parameters in a variable cross section channel in gas mixture of methane with oxygen and nitrogen

    OpenAIRE

    G. Y. Bivol; V. S. Golovastov; A. Yu. Mikushkin

    2014-01-01

    Propagation of the detonation wave in gas mixtures of methane with oxygen in a channel of variable cross section was studied experimentally. To conduct these investigations a special detonation combustion chamber comprising sections of various diameters has been designed. In the section of detonation wave formation a combustible mixture was ignited. After that, a flame front accelerated till the formation of detonation. At the exit from the combustion chamber there was an outlet conical secti...

  4. Conditional Frequentist Test on Normal Mean Parameter and its application in entomological data

    Directory of Open Access Journals (Sweden)

    Carla R. G. Brighenti

    2014-10-01

    Full Text Available In the traditional tests the value of type I error (α is fixed, on the other hand, in the conditional frequentist test we propose a partition of the region of rejection and acceptance so that the probability of error presented is dependent on the distance of observed data in relation to the border of the critical region. This error probability is the Conditional Error Probability (CEP, which may be of type I or II. The objective of this study was to evaluate the behavior of the conditional frequentist test under the Normal Mean parameter and apply it to entomological data. The test was evaluated via simulation, from developed routine in R software. In each simulated case obtained the likelihood ratio, the critical value and the PEC’s for the Normal distribution. It was concluded that the highest values of PEC were obtained with the more the sample mean value approaching the critical point of the test. This occurs regardless of the decision of the test to accept or reject the null hypothesis. The increase of the sample size causes the reduction of the conditional probability of error. In the application to real data from the average lifetime of bees exposed to different temperatures, it was found that the average lifetime of bees maintained at a temperature of 20°C was found to be similar at a temperature of 15°C with conditional error very small (CEP II equal to 0.54%. For temperatures of 30°C and 35°C the hypothesis was rejected with PEC I equal to 28.35% and 47.53%, respectively. Thus the conditional errors in decision making were very high.

  5. Lexical patterns in the reading comprehension section of the toefl test

    Directory of Open Access Journals (Sweden)

    Fabiana Macmillan

    2006-11-01

    Full Text Available The TOEFL (Test of English as a Foreign Language is currently one of the most widely accepted English language proficiency tests. Designed by the ETS (Educational Testing Service, the main purpose of the TOEFL is to determine whether the English language skills of a student applying to a North American college or university are adequate for enrollment into the selected program of study. This study will focus upon the third section of the TOEFL, Reading Comprehension, which consists of several passages followed by questions with different testing purposes. An adaptation of Hoey's (1991 analytical system for the analysis of lexical cohesion in authentic texts will be used to identify bonds connecting reading comprehension questions on the test to key excerpts in the passages they are related to. A number of sample reading comprehension questions taken from practice tests produced by the ETS will be analyzed. The analysis will focus on the relationship between the testing purpose of each question and the type(s of lexical link involved in the identification of the correct answer.

  6. Analytical Validation of AmpliChip p53 Research Test for Archival Human Ovarian FFPE Sections.

    Directory of Open Access Journals (Sweden)

    Matthew J Marton

    Full Text Available The p53 tumor suppressor gene (TP53 is reported to be mutated in nearly half of all tumors and plays a central role in genome integrity. Detection of mutations in p53 can be accomplished by many assays, including the AmpliChip p53 Research Test. The AmpliChip p53 Research Test has been successfully used to determine p53 status in hematologic malignancies and fresh frozen solid tissues but there are few reports of using the assay with formalin fixed, paraffin-embedded (FFPE tissue. The objective of this study was to describe analytical performance characterization of the AmpliChip p53 Research Test to detect p53 mutations in genomic DNA isolated from archival FFPE human ovarian tumor tissues. Method correlation with sequencing showed 96% mutation-wise agreement and 99% chip-wise agreement. We furthermore observed 100% agreement (113/113 of the most prevalent TP53 mutations. Workflow reproducibility was 96.8% across 8 samples, with 2 operators, 2 reagent lots and 2 instruments. Section-to-section reproducibility was 100% for each sample across a 60 μm region of the FFPE block from ovarian tumors. These data indicate that the AmpliChip p53 Research Test is an accurate and reproducible method for detecting mutations in TP53 from archival FFPE human ovarian specimens.

  7. Analytical Validation of AmpliChip p53 Research Test for Archival Human Ovarian FFPE Sections.

    Science.gov (United States)

    Marton, Matthew J; McNamara, Andrew R; Nikoloff, D Michele; Nakao, Aki; Cheng, Jonathan

    2015-01-01

    The p53 tumor suppressor gene (TP53) is reported to be mutated in nearly half of all tumors and plays a central role in genome integrity. Detection of mutations in p53 can be accomplished by many assays, including the AmpliChip p53 Research Test. The AmpliChip p53 Research Test has been successfully used to determine p53 status in hematologic malignancies and fresh frozen solid tissues but there are few reports of using the assay with formalin fixed, paraffin-embedded (FFPE) tissue. The objective of this study was to describe analytical performance characterization of the AmpliChip p53 Research Test to detect p53 mutations in genomic DNA isolated from archival FFPE human ovarian tumor tissues. Method correlation with sequencing showed 96% mutation-wise agreement and 99% chip-wise agreement. We furthermore observed 100% agreement (113/113) of the most prevalent TP53 mutations. Workflow reproducibility was 96.8% across 8 samples, with 2 operators, 2 reagent lots and 2 instruments. Section-to-section reproducibility was 100% for each sample across a 60 μm region of the FFPE block from ovarian tumors. These data indicate that the AmpliChip p53 Research Test is an accurate and reproducible method for detecting mutations in TP53 from archival FFPE human ovarian specimens.

  8. Four-Point Bending Strength Testing of Pultruded Fiberglass Composite Wind Turbine Blade Sections

    Energy Technology Data Exchange (ETDEWEB)

    Musial, W.; Bourne, B; Hughes, S; Zuteck, M. D. (MDZ Consulting)

    2001-07-10

    The ultimate strength of the PS Enterprises pultruded blade section was experimentally determined under four-point bending at the National Renewable Energy Laboratory. Thirteen 8-foot long full-scale blade segments were individually tested to determine their maximum moment carrying capability. Three airfoil-bending configurations were tested: high- and low-pressure skin buckling, and low pressure skin buckling with foam interior reinforcement. Maximum strain was recorded for each sample on the compressive and tensile surfaces of each test blade. Test data are compared to the results of three analytical buckling prediction methods. Based on deviations from the linear strain versus load curve, data indicate a post-buckling region. High-pressure side buckling occurred sooner than low-pressure side buckling. The buckling analyses were conservative for both configurations, but high-pressure side buckling in particular was substantially under-predicted. Both high- and low-pressure buckling configurations had very similar failure loads. These results suggests that a redundant load path may be providing strength to the section in the post-buckling region, making the onset of panel buckling a poor predictor of ultimate strength for the PS Enterprises pultrusion.

  9. TIME-OF-DAY EFFECTS ON EMG PARAMETERS DURING THE WINGATE TEST IN BOYS

    Directory of Open Access Journals (Sweden)

    Hichem Souissi

    2012-09-01

    Full Text Available In boys, muscle power and strength fluctuate with time-of-day with morning nadirs and afternoon maximum values. However, the exact underlying mechanisms of this daily variation are not studied yet. Thus, the purpose of this study was to examine the time-of-day effects on electromyographic (EMG parameters changes during a Wingate test in boys. Twenty-two boys performed a 30-s Wingate test (measurement of muscle power and fatigue at 07:00 and 17:00-h on separate days. Surface EMG activity was recorded in the Vastus lateralis, rectus femoris and vastus medialis muscles throughout the test and analyzed over a 5-s span. The root-mean-square (RMS and mean-power-frequency (MPF were calculated. Neuromuscular efficiency (NME was estimated from the ratio of power to RMS. Muscle power (8.22 ± 0.92 vs. 8.75 ± 0.99 W·kg-1 for peak power and 6.96 ± 0. 72 vs. 7.31 ± 0.77 W·kg-1 for mean power, p < 0.001 and fatigue (30.27 ± 7.98 vs. 34.5 ± 10. 15 %, p < 0.05 during the Wingate test increased significantly from morning to evening. Likewise, MPF (102.14 ± 18.15 vs. 92.38 ± 12.39 Hz during the first 5-s, p < 0.001 and NME (4.78 ± 1.7 vs. 3.88 ± 0.79 W·mV-1 during the first 5-s, p < 0.001 were higher in the evening than the morning; but no significant time-of-day effect was noticed for RMS. Taken together, these results suggest that peripheral mechanisms are more likely the cause of the child's diurnal variations of muscle power and fatigue during the Wingate test

  10. Drop test analysis of fuselage section of R80 commuter aircraft by using finite element method

    Science.gov (United States)

    Anggono, Agus Dwi; Ardianto, Adik Nofa Rochma Wahyu

    2017-04-01

    In commercial aerospace development, feasibility accidents design or crashworthiness is a major concern in aviation safety. Fuselage structure plays an important role in absorbing energy during an accident. The research aims are to determine drop test phenomenon on the fuselage, to investigate deformation occurred in the structure of the fuselage, and to know the influence of the airframe falls position to the stress strain which occurred in the structure of the fuselage. This research was conducted by varying the fall angle of the fuselage in a vertical position or 0° and 15°. Fuselage design was modeled by using SolidWorks. Then the model is imported to the Abaqus for drop test simulation. From the simulation results, it can be obtained the phenomenon of deformation on the structure of the fuselage when it comes in contact with the rigid ground. The high deformation occurs shows the structure capabilities in order to absorb the impact. It could be happened because the deformation is influenced by internal energy and strain energy. The various positions shows the structure capability in order to withstand impact loads during periods of 4-8 seconds and the maximum deformation was reached in 12 seconds. The experiment on the vertical position and the position falls of 15° angle was delivered the highest stress strain. The stress was 483 MPa in struts section, 400.78 MPa in skin section, 358.28 MPa in the floor and 483 MPa in the cargo frame section.

  11. Fracture Toughness of Thick Boride Layers Estimated by the Cross-Sectioned Scratch Test

    Science.gov (United States)

    Campos-Silva, I.; Flores-Jiménez, M.; Bravo-Bárcenas, D.; Rodríguez-Castro, G.; Martínez-Trinidad, J.; Meneses-Amador, A.

    2018-01-01

    New results about the fracture toughness (K c) of thick boride layers estimated by the cross-sectioned scratch test are presented in this study. The FeB-Fe2B layers developed at the surface of borided AISI 1018 and AISI 1045 steels and the Fe2B layer formed on the borided AISI 1045 steel exposed to a diffusion annealing process (DAP) were used for this purpose. The cross-sectioned scratch tests were performed with a Vickers diamond stylus drawn across the thick boride layer under a constant load to produce a half-cone-shaped fracture near to the top surface of the borided steels. The height of the half-cone-shaped fracture as a function of the cross-sectioned scratch loads was used to determine the fracture toughness of the FeB and Fe2B layers. The results showed a fracture resistance of ˜2.8 {MPa}√ m for the FeB layer formed at the surface of borided AISI 1045 steel. Likewise, the effect of the DAP on the surface of the borided AISI 1045 steel promoted the formation of an exclusively Fe2B layer, with an increase in the fracture toughness of the whole boride layer around 5 {MPa}√ m . Finally, the principle of the technique can be used to minimize the influence of the anisotropic properties on the fracture toughness along the depth of boride layers.

  12. Leather for motorcyclist garments: Multi-test based material model fitting in terms of Ogden parameters

    Directory of Open Access Journals (Sweden)

    Bońkowski T.

    2017-12-01

    Full Text Available This paper is focused on experimental testing and modeling of genuine leather used for a motorcycle personal protective equipment. Simulations of powered two wheelers (PTW accidents are usually performed using human body models (HBM for the injury assessment equipped only with the helmet model. However, the kinematics of the PTW rider during a real accident is disturbed by the stiffness of his suit, which is normally not taken into account during the reconstruction or simulation of the accident scenario. The material model proposed in this paper can be used in numerical simulations of crash scenarios that include the effect of motorcyclist rider garment. The fitting procedure was conducted on 2 sets of samples: 5 uniaxial samples and 5 biaxial samples. The experimental characteristics were used to obtain the set of 25 constitutive material models in terms of Ogden parameters.

  13. The Influence Of Temperature Gradient On Stereological Parameters Of Carbide Phase On Cross-Section Of Abrasive Wear Resistant Chromium Cast Iron

    Directory of Open Access Journals (Sweden)

    Studnicki A.

    2015-09-01

    Full Text Available In the paper analysis of temperature gradient and parameters of structure on casting cross-section of abrasive wear resistant chromium cast iron at carbon content of 2,5%wt. and chromium 17%wt. with nickel and molybdenum additives are presented. The castings were made with use of special tester ϕ100mm (method of temperature gradient and derivative analysis with temperature recording in many points from thermal centre to surface (to mould of casting. Registered cooling curves were used to describe the temperature gradient on cross-section of analyzed casting. On the basis of determined curves of temperature gradient measurement fields were selected to make the quantitative studies of structure. The results of studies show significant influence of temperature gradient on quantitative parameters of chromium cast iron structure. Moreover was affirmed that exists a critical temperature gradient for which is present rapid change of quantitative parameters of chromium cast iron structure.

  14. Development and Testing of Neutron Cross Section Covariance Data for SCALE 6.2

    Energy Technology Data Exchange (ETDEWEB)

    Marshall, William BJ J [ORNL; Williams, Mark L [ORNL; Wiarda, Dorothea [ORNL; Rearden, Bradley T [ORNL; Dunn, Michael E [ORNL; Mueller, Don [ORNL; Clarity, Justin B [ORNL; Jones, Elizabeth L [ORNL

    2015-01-01

    Neutron cross-section covariance data are essential for many sensitivity/uncertainty and uncertainty quantification assessments performed both within the TSUNAMI suite and more broadly throughout the SCALE code system. The release of ENDF/B-VII.1 included a more complete set of neutron cross-section covariance data: these data form the basis for a new cross-section covariance library to be released in SCALE 6.2. A range of testing is conducted to investigate the properties of these covariance data and ensure that the data are reasonable. These tests include examination of the uncertainty in critical experiment benchmark model keff values due to nuclear data uncertainties, as well as similarity assessments of irradiated pressurized water reactor (PWR) and boiling water reactor (BWR) fuel with suites of critical experiments. The contents of the new covariance library, the testing performed, and the behavior of the new covariance data are described in this paper. The neutron cross-section covariances can be combined with a sensitivity data file generated using the TSUNAMI suite of codes within SCALE to determine the uncertainty in system keff caused by nuclear data uncertainties. The Verified, Archived Library of Inputs and Data (VALID) maintained at Oak Ridge National Laboratory (ORNL) contains over 400 critical experiment benchmark models, and sensitivity data are generated for each of these models. The nuclear data uncertainty in keff is generated for each experiment, and the resulting uncertainties are tabulated and compared to the differences in measured and calculated results. The magnitude of the uncertainty for categories of nuclides (such as actinides, fission products, and structural materials) is calculated for irradiated PWR and BWR fuel to quantify the effect of covariance library changes between the SCALE 6.1 and 6.2 libraries. One of the primary applications of sensitivity/uncertainty methods within SCALE is the

  15. HIV testing and tolerance to gender based violence: a cross-sectional study in Zambia.

    Directory of Open Access Journals (Sweden)

    Sara Gari

    Full Text Available This paper explores the effect of social relations and gender-based conflicts on the uptake of HIV testing in the South and Central provinces of Zambia. We conducted a community-based cross-sectional study of 1716 randomly selected individuals. Associations were examined using mixed-effect multivariable logistic regression. A total of 264 men (64% and 268 women (56% had never tested for HIV. The strongest determinants for not being tested were disruptive couple relationships (OR = 2.48 95% CI = 1.00-6.19; tolerance to gender-based violence (OR = 2.10 95% CI = 1.05-4.32 and fear of social rejection (OR = 1.48 95% CI = 1.23-1.80. In the Zambian context, unequal power relationships within the couple and the community seem to play a pivotal role in the decision to test which until now have been largely underestimated. Policies, programs and interventions to rapidly increase HIV testing need to urgently address gender-power inequity in relationships and prevent gender-based violence to reduce the negative impact on the lives of couples and families.

  16. Effect of High-Humidity Testing on Material Parameters of Flexible Printed Circuit Board Materials

    Science.gov (United States)

    Lahokallio, Sanna; Saarinen, Kirsi; Frisk, Laura

    2013-09-01

    The tendency of polymers to absorb moisture impairs especially their electrical and mechanical properties. These are important characteristics for printed circuit board (PCB) materials, which should provide mechanical support as well as electrical insulation in many different environments in order to guarantee safe operation for electrical devices. Moreover, the effects of moisture are accelerated at increased temperatures. In this study, three flexible PCB dielectric materials, namely polyimide (PI), fluorinated ethylene-propylene (FEP), and polyethylene terephthalate (PET), were aged over different periods of time in a high-humidity test, in which the temperature was 85°C and relative humidity 85%. After aging, the changes in the structure of the polymers were studied by determining different material parameters such as modulus of elasticity, glass-transition temperature, melting point, coefficient of thermal expansion, water absorption, and crystallinity, and changes in the chemical structure with several techniques including thermomechanical analysis, differential scanning calorimetry, Fourier-transform infrared spectroscopy, moisture analysis, and a precision scale. The results showed that PI was extremely stable under the aging conditions and therefore an excellent choice for electrical applications under harsh conditions. Similarly, FEP proved to be relatively stable under the applied aging conditions. However, its crystallinity increased markedly during aging, and after 6000 h of aging the results indicated oxidation. PET suffered from hydrolysis during the test, leading to its embrittlement after 2000 h of aging.

  17. [Basophil degranulation test (BDT) as a parameter of hyposensitization with Hymenoptera venoms].

    Science.gov (United States)

    Dietschi, R; Wüthrich, B; Marti-Wyss, S; Cuhat, J

    1987-10-31

    In a population of 24 insect sting allergy patients undergoing venom immunotherapy the basophil degranulation test (BDT) in the patient sera ("unwashed" BDT) and with washed leukocytes ("washed" BDT) after incubation with bee and wasp (yellow jacket) venom was performed before and during treatment. Venom specific IgE and IgG antibodies, detected by means of RAST, were also monitored. The "unwashed" BDT usually became negative within 6-9 months of beginning immunotherapy, whereas the IgE-RAST was still clearly positive. This was attributed to the blocking influence of the venom specific IgG antibodies induced by the venom therapy. In fact, at this time the BDT with "washed" blood leukocytes, i.e. after elimination of the serum antibodies, was generally still positive. Only during further immunotherapy did cellular sensitization in the "washed" BDT gradually disappear, whereas the IgE-RAST usually turned out weakly positive. A third of the patients showed simultaneously negative results of "unwashed" and "washed" BDT, independently of venom specific IgE and IgG levels. These findings suggest a specific reactivity change of the blood basophils (cellular desensitization) induced by the immunotherapy. The BDT can be used as an immunological parameter for IgG-monitoring of the course of venom immunotherapy and--in addition to skin tests and IgE-RAST--as a further criterion for deciding to stop venom therapy if it turns negative with the washed cells.

  18. Tests of a New Drowsiness Characterization and Monitoring System Based on Ocular Parameters

    Directory of Open Access Journals (Sweden)

    Clémentine François

    2016-01-01

    Full Text Available Drowsiness is the intermediate state between wakefulness and sleep. It is characterized by impairments of performance, which can be very dangerous in many activities and can lead to catastrophic accidents in transportation or in industry. There is thus an obvious need for systems that are able to continuously, objectively, and automatically estimate the level of drowsiness of a person busy at a task. We have developed such a system, which is based on the physiological state of a person, and, more specifically, on the values of ocular parameters extracted from images of the eye (photooculography, and which produces a numerical level of drowsiness. In order to test our system, we compared the level of drowsiness determined by our system to two references: (1 the level of drowsiness obtained by analyzing polysomnographic signals; and (2 the performance of individuals in the accomplishment of a task. We carried out an experiment in which 24 participants were asked to perform several Psychomotor Vigilance Tests in different sleep conditions. The results show that the output of our system is well correlated with both references. We determined also the best drowsiness level threshold in order to warn individuals before they reach dangerous situations. Our system thus has significant potential for reliably quantifying the level of drowsiness of individuals accomplishing a task and, ultimately, for preventing drowsiness-related accidents.

  19. Body Mass Index-Dependent Ventilatory Parameters From Respiratory Inductive Plethysmography During 6-Minute Walk Test.

    Science.gov (United States)

    Retory, Yann; de Picciotto, Carole; Niedzialkowski, Pauline; Petitjean, Michel; Bonay, Marcel

    2016-04-01

    Walking is part of obesity management. Assessment of ventilatory impairments and consequences for gait induced by obesity could be clinically helpful. We aimed to develop a method to accurately monitor ventilation with respiratory inductive plethysmography (RIP) in subjects with high body mass indices (BMIs) during a 6-min walk test (6MWT). 25 volunteers were divided into 2 groups based on BMI (30 kg/m2) and performed a 6MWT with a calibrated RIP. Ventilatory parameters (tidal volume [V(T)], inspiratory [T(I)] and expiratory [T(E)] times, V(T)/T(I) ratio, and T(I)/Ttot ratio) were determined after processing RIP signals with a custom-made algorithm designed to discriminate tissue motion artifacts and respiratory cycles in the time domain. Six-min walk distance and average speed by minute were collected. The number of artifacts removed by the algorithm used for artifact removal was higher for high-BMI subjects and was correlated to their individual values (r = 0.66, P exercise for V(T), T(I), and T(E) (P exercise as well as locomotor and ventilatory differences relative to BMI during the 6MWT. Thus, this system gives useful information from the 6MWT for clinicians who want to assess respiratory patterns of patients during this commonly used test. Copyright © 2016 by Daedalus Enterprises.

  20. Multi-parameter in vitro toxicity testing of crizotinib, sunitinib, erlotinib, and nilotinib in human cardiomyocytes

    Energy Technology Data Exchange (ETDEWEB)

    Doherty, Kimberly R., E-mail: kimberly.doherty@quintiles.com [Quintiles, 777 Oakmont Lane Suite 100, Westmont, IL 60559 (United States); Wappel, Robert L.; Talbert, Dominique R.; Trusk, Patricia B.; Moran, Diarmuid M. [Quintiles, 777 Oakmont Lane Suite 100, Westmont, IL 60559 (United States); Kramer, James W.; Brown, Arthur M. [ChanTest Corporation, 14656 Neo Parkway, Cleveland, OH 44128 (United States); Shell, Scott A.; Bacus, Sarah [Quintiles, 777 Oakmont Lane Suite 100, Westmont, IL 60559 (United States)

    2013-10-01

    Tyrosine kinase inhibitors (TKi) have greatly improved the treatment and prognosis of multiple cancer types. However, unexpected cardiotoxicity has arisen in a subset of patients treated with these agents that was not wholly predicted by pre-clinical testing, which centers around animal toxicity studies and inhibition of the human Ether-à-go-go-Related Gene (hERG) channel. Therefore, we sought to determine whether a multi-parameter test panel assessing the effect of drug treatment on cellular, molecular, and electrophysiological endpoints could accurately predict cardiotoxicity. We examined how 4 FDA-approved TKi agents impacted cell viability, apoptosis, reactive oxygen species (ROS) generation, metabolic status, impedance, and ion channel function in human cardiomyocytes. The 3 drugs clinically associated with severe cardiac adverse events (crizotinib, sunitinib, nilotinib) all proved to be cardiotoxic in our in vitro tests while the relatively cardiac-safe drug erlotinib showed only minor changes in cardiac cell health. Crizotinib, an ALK/MET inhibitor, led to increased ROS production, caspase activation, cholesterol accumulation, disruption in cardiac cell beat rate, and blockage of ion channels. The multi-targeted TKi sunitinib showed decreased cardiomyocyte viability, AMPK inhibition, increased lipid accumulation, disrupted beat pattern, and hERG block. Nilotinib, a second generation Bcr-Abl inhibitor, led to increased ROS generation, caspase activation, hERG block, and an arrhythmic beat pattern. Thus, each drug showed a unique toxicity profile that may reflect the multiple mechanisms leading to cardiotoxicity. This study demonstrates that a multi-parameter approach can provide a robust characterization of drug-induced cardiomyocyte damage that can be leveraged to improve drug safety during early phase development. - Highlights: • TKi with known adverse effects show unique cardiotoxicity profiles in this panel. • Crizotinib increases ROS, apoptosis, and

  1. The design of test-section inserts for higher speed aeroacoustic testing in the Ames 80- by 120-Foot Wind Tunnel

    Science.gov (United States)

    Soderman, Paul T.; Olson, Larry E.

    1992-01-01

    An engineering feasibility study was made of aeroacoustic inserts designed for large-scale acoustic research on aircraft models in the 80- by 120 Foot Wind Tunnel at NASA Ames Research Center. The goal was to find test-section modifications that would allow improved aeroacoustic testing at airspeeds equal to and above the current 100 knots limit. Results indicate that the required maximum airspeed drives the design of a particular insert. Using goals of 200, 150, and 100 knots airspeed, the analysis led to a 30 x 60 ft open-jet test section, a 40 x 80 ft open-jet test section, and a 70 x 110 ft closed test section with enhanced wall lining respectively. The open-jet inserts would be composed of a nozzle, collector, diffuser, and acoustic wedges incorporated in the existing 80 x 120 ft test section. The closed test section would be composed of approximately 5-ft acoustic wedges covered by a porous plate attached to the test-section walls of the existing 80 x 120. All designs would require a double row of acoustic vanes between the test section and fan drive to attenuate fan noise and, in the case of the open-jet designs, to control flow separation at the diffuser downstream end. The inserts would allow virtually anechoic acoustics studies of large helicopter models, jets and V/STOL aircraft models in simulated flight. Model scale studies would be necessary to optimize the aerodynamic and acoustic performance of any of the designs.

  2. The use of predicted values for item parameters in item response theory models: An application in intelligence tests

    NARCIS (Netherlands)

    Matteucci, M.; S. Mignani, Prof.; Veldkamp, Bernard P.

    2012-01-01

    In testing, item response theory models are widely used in order to estimate item parameters and individual abilities. However, even unidimensional models require a considerable sample size so that all parameters can be estimated precisely. The introduction of empirical prior information about

  3. Primary care patient willingness for genetic testing for salt-sensitive hypertension: a cross sectional study.

    Science.gov (United States)

    Okayama, Masanobu; Takeshima, Taro; Ae, Ryusuke; Harada, Masanori; Kajii, Eiji

    2013-10-09

    The current research into single nucleotide polymorphisms has extended the role of genetic testing to the identification of increased risk for common medical conditions. Advances in genetic research may soon necessitate preparation for the role of genetic testing in primary care medicine. This study attempts to determine what proportion of patients would be willing to undergo genetic testing for salt-sensitive hypertension in a primary care setting, and what factors are related to this willingness. A cross-sectional study using a self-report questionnaire was conducted among outpatients in primary care clinics and hospitals in Japan. The main characteristics measured were education level, family medical history, personal medical history, concern about hypertension, salt preference, reducing salt intake, and willingness to undergo genetic testing for salt-sensitive hypertension. Of 1,932 potential participants, 1,457 (75%) responded to the survey. Of the respondents, 726 (50%) indicated a willingness to undergo genetic testing. Factors related to this willingness were being over 50 years old (adjusted odds ratio [ad-OR] = 1.42, 95% Confidence interval = 1.09 - 1.85), having a high level of education (ad-OR: 1.83, 1.38 - 2.42), having a family history of hypertension (ad-OR: 1.36, 1.09 - 1.71), and worrying about hypertension (ad-OR: 2.06, 1.59 - 2.68). Half of the primary care outpatients surveyed in this study wanted to know their genetic risk for salt-sensitive hypertension. Those who were worried about hypertension or had a family history of hypertension were more likely to be interested in getting tested. These findings suggest that primary care physicians should provide patients with advice on genetic testing, as well as address their anxieties and concerns related to developing hypertension.

  4. Performing Pumping Test Data Analysis Applying Cooper-Jacob’s Method for Estimating of the Aquifer Parameters

    National Research Council Canada - National Science Library

    Khider Mawlood Dana; Sabah Mustafa Jwan

    2016-01-01

    ... Transmissivity, but the other parameter which is Storativity is overestimated, so the aim of this study is to analyze four pumping test data located in KAWRGOSK area by using cooper-Jacob’s (1946...

  5. Semipalatinsk test site: Parameters of radionuclide transfer to livestock and poultry products under actual radioactive contamination

    Energy Technology Data Exchange (ETDEWEB)

    Baigazinov, Z.; Lukashenko, S. [Institute of Radiation Safety and Ecology (Kazakhstan)

    2014-07-01

    The IAEA document 'Handbook of Parameter Values for the Prediction of Radionuclide Transfer in Terrestrial and Freshwater Environments' published in 2010 is one of the major sources of knowledge about the migration parameters of radionuclides in the agro-ecosystems that is necessary to assess the dose loads to the population. It is known from there that Sr and Cs transfer has been studied thoroughly, however the factors vary over a wide range. Few studies were conducted for Pu and Am transfer. It should be noted that the studies carried out in real conditions of radioactive contamination, i.e. under natural conditions is also very few. In this regard, since 2007 the territory of the former Semipalatinsk Test Site has been used for comprehensive radioecological studies, where the major radionuclides to be investigated are {sup 90}Sr, {sup 137}Cs, {sup 239+240}Pu, {sup 241}Am. The objects for these studies are birds and animals typical for the region, as well as products obtained from them (lamb, beef, horse meat, chicken, pork, cow's milk, mare's milk, eggs, chicken, chicken feathers, wool, leather). It should be noted that these products are the main agricultural goods that are available in these areas. The studies have been conducted with grazing animals in the most contaminated areas of the test site. Some groups of animals and birds were fed to contaminated feed, soil, contaminated water. Radionuclide intake by animal body with air were studied. Husbandry periods for animals and birds ranged from 1 to 150 days. The transfer parameters to cow and mare's milk have been investigated at single and prolonged intake of radionuclides, also their excretion dynamics has been studied. The studies revealed features of the radionuclide transfer into organs and tissues of animals and birds intaken with hay, water and soil. The results showed that the transfer factors vary up to one order. A relationship has been identified between distribution of

  6. Gas migration in KBS-3 buffer bentonite. Sensitivity of test parameters to experimental boundary conditions

    Energy Technology Data Exchange (ETDEWEB)

    Harrington, J.F.; Horseman, S.T. [British Geological Survey, Nottingham (United Kingdom)

    2003-01-01

    In the current Swedish repository design concept, hydrogen gas can be generated inside a waste canister by anaerobic corrosion of the ferrous metal liner. If the gas generation rate exceeds the diffusion rate of gas molecules in the buffer porewater, gas will accumulate in the void-space of a canister until its pressure becomes large enough for it to enter the bentonite as a discrete gaseous phase. Three long tenn gas injection tests have been performed on cylinders of pre-compacted MX80 bentonite. Two of these tests were undertaken using a custom-designed constant volume and radial flow (CVRF) apparatus. Gas was injected at a centrally located porous filter installed in the clay before hydration. Arrangements were made for gas to flow to three independently monitored sink-filter arrays mounted around the specimen. Axial and radial total stresses and internal porewater pressures were continuously monitored. Breakthrough and peak gas pressures were substantially larger than the sum of the swelling pressure and the external porewater. The third test was performed. using an apparatus which radially constrains the specimen during gas flow. Observed sensitivity of the breakthrough and peak gas pressures to the test boundary conditions suggests that gas entry must be accompanied by dilation of the bentonite fabric. In other words, there is a tendency for the volume of the specimen to increase during this process. The experimental evidence is consistent with the flow of gas along a relatively small number of crack-like pathways which propagate through the clay as gas pressure increases. Gas entry and breakthrough under constant volume boundary conditions causes a substantial increase in the total stress and the internal porewater pressure. It is possible to determine the point at which gas enters the clay by monitoring changes in these parameters. Localisation of gas flow within multiple pathways results, in nonuniform discharge rates at the sinks. When gas injection

  7. Control parameters of the martian dune field positions at planetary scale: tests by the MCD

    Science.gov (United States)

    allemand, pascal

    2016-04-01

    The surface of Mars is occupied by more than 500 dunes fields mainly located inside impact craters of the south hemisphere and near the north polar cap. The questions of the activity of martian dunes and of the localization of the martian dune fields are not completely solved. It has been demonstrated recently by image observation and image correlation that some of these dune fields are clearly active. The sand flux of one of them has been even estimated. But there is no global view of the degree of activity of each the dune fields. (2)The topography of impact craters in which dune fields are localized is an important factor of their position. But there is no consensus of the effect of global atmospheric circulation on dune field localization. These two questions are addressed using the results of Mars Climate Database 5.2 (MCD) (Millour, 2015; Forget et al., 1999). The wind fields of the MCD have been first validated against the observations made on active dune fields. Using a classical transport law, the Drift Potential (DP) and the Relative Drift Potential (RDP) have been computed for each dune fields. A good correlation exists between the position of dune fields and specific values of these two parameters. The activity of each dune field is estimated from these parameters and tested on some examples by image observations. Finally a map of sand flow has been computed at the scale of the planet. This map shows that sand and dust is trapped in specific regions. These regions correspond to the area of dune field concentration.

  8. 26 CFR 1.1502-98A - Coordination with section 383 generally applicable for testing dates (or members joining or...

    Science.gov (United States)

    2010-04-01

    ... applicable for testing dates (or members joining or leaving a group) before June 25, 1999. 1.1502-98A Section 1.1502-98A Internal Revenue INTERNAL REVENUE SERVICE, DEPARTMENT OF THE TREASURY (CONTINUED) INCOME... section 383 generally applicable for testing dates (or members joining or leaving a group) before June 25...

  9. Performance and test section flow characteristics of the National Full-Scale Aerodynamics Complex 80- by 120-Foot Wind Tunnel

    Science.gov (United States)

    Zell, Peter T.

    1993-01-01

    Results from the performance and test section flow calibration of the 80- by 120-Foot Wind Tunnel are presented. Measurements indicating the 80- by 120-ft test section flow quality were obtained throughout the tunnel operational envelope and for atmospheric wind speeds up to approximately 20 knots. Tunnel performance characteristics and a dynamic pressure system calibration were also documented during the process of mapping the test section flow field. Experimental results indicate that the test section flow quality is relatively insensitive to dynamic pressure and the level of atmospheric winds experienced during the calibration. The dynamic pressure variation in the test section is within +/-75 percent of the average. The axial turbulence intensity is less than 0.5 percent up to the maximum test section speed of 100 knots, and the vertical and lateral flow angle variations are within +/-5 deg and +/-7 deg, respectively. Atmospheric winds were found to affect the pressure distribution in the test section only at high ratios of wind speed to test section speed.

  10. Performing Pumping Test Data Analysis Applying Cooper-Jacob’s Method for Estimating of the Aquifer Parameters

    Directory of Open Access Journals (Sweden)

    Dana Khider Mawlood

    2016-06-01

    Full Text Available Single well test is more common than aquifer test with having observation well, since the advantage of single well test is that the pumping test can be conducted on the production well with the absence of observation well. A kind of single well test, which is step-drawdown test used to determine the efficiency and specific capacity of the well, however in case of single well test it is possible to estimate Transmissivity, but the other parameter which is Storativity is overestimated, so the aim of this study is to analyze four pumping test data located in KAWRGOSK area by using cooper-Jacob’s (1946 time drawdown approximation of Theis method to estimate the aquifer parameters, also in order to determine the reasons which are affecting the reliability of the Storativity value and obtain the important aspect behind that in practice.

  11. Kinetic parameter determination of roasted and unroasted argan oil oxidation under Rancimat test conditions

    Directory of Open Access Journals (Sweden)

    Zaanoun, I.

    2014-09-01

    Full Text Available The present study investigated the Kinetic parameter determination of edible argan oil (coldpressed from roasted argan kernels and cosmetic argan oil (cold-pressed from unroasted argan kernels under the Rancimat test conditions. The physicochemical parameters of edible and cosmetic argan oil immediately after preparation and after accelerated oxidation test Rancimat at different temperatures 90 °C, 100 °C, 110 °C, 120 °C, 130 °C and 140 °C were determined and compared. The natural logarithms of the kinetic rate constant (kvalue varied linearly with respect to temperature. An increasing rate of oxidation could be observed as temperature increased. On the basis of the Arrhenius equation and the activated complex theory, frequency factors A, activation energies Ea, Q10 numbers, activation enthalpies ΔH, and activation entropies ΔS for oxidative stability of the vegetable oils were calculated. The accelerated oxidation and Kinetic parameters have shown that edible argan oil can be stored much better than cosmetic oil.En presente estudio se determinaron los parámetros cinéticosde aceites de argán comestible (prensado en frío a partir de granos tostados de argán y cosmético (prensado en frío a partir de granos de argán sin tostar bajo las condiciones del método Rancimat. Se determinó y comparó los parámetros físico-químicos de aceites de argán comestible y cosmético inmediatamente después de la preparación y después de la oxidación acelerada mediante Rancimat a temperaturas de 90 °C, 100 °C, 110 °C, 120 °C, 130 °C y 140 °C Los logaritmos naturales de la constante de velocidad cinética (valor k variaron linealmente con respecto a la temperatura. Se pudo observar un valor creciente de la oxidación conel aumento de la temperatura. Se calculó para la estabilidad oxidativa de los aceites vegetalesy sobre la base de la ecuación de Arrhenius y la teoría del complejo activado, la frecuencia de los factores A, energ

  12. Factors affecting voluntary HIV counselling and testing among men in Ethiopia: a cross-sectional survey

    Directory of Open Access Journals (Sweden)

    Leta Tesfaye H

    2012-06-01

    Full Text Available Abstract Background Voluntary HIV counselling and testing (VCT is one of the key strategies in the HIV/AIDS prevention and control programmes in Ethiopia. However, utilization of this service among adults is very low. The aim of the present study was to investigate factors associated with VCT utilization among adult men since men are less likely than women to be offered and accept routine HIV testing. Methods The study utilized data from the Ethiopian Demographic Health Survey (EDHS 2005, which is a cross-sectional survey conducted on a nationally representative sample. Using cluster sampling, 6,778 men aged 15–59 years were selected from all the eleven administrative regions in Ethiopia. Logistic regression was used to analyze potential factors associated with VCT utilization. Results Overall, 21.9% of urban men and 2.6% of rural men had ever tested for HIV through VCT and most of them had learned their HIV test result. Having no stigmatizing attitudes toward people living with HIV/AIDS was found to be strongly and positively associated with VCT utilization in both urban and rural strata. In rural areas HIV test rates were higher among younger men (aged ≤44 years and those of higher socio-economic position (SEP. Among urban men, risky sexual behaviour was positively associated with VCT utilization whereas being Muslim was found to be inversely associated with utilization of VCT. Area of residence as well as SEP strongly affected men’s level of stigmatizing attitudes toward people living with HIV/AIDS. Conclusions VCT utilization among men in Ethiopia was low and affected by HIV/AIDS-related stigma and residence. In order to increase VCT acceptability, HIV/AIDS prevention and control programs in the country should focus on reducing HIV/AIDS-related stigma. Targeting rural men with low SEP should be given first priority when designing, expanding, and implementing VCT services in the country.

  13. Basement of Structure, Main Power and Design Parameters of Mechanism of Removing Sections of Mechanized Sets of Knife Plane Installation

    Science.gov (United States)

    Sysoev, N. I.; Turuk, Yu V.; Kolesnichenko, I. Y.; Lugantsev, B. B.

    2017-10-01

    The reasons for the failure of the pitch stability of the knife-plane installation due to the action of extreme effort in the plane of the seam from the conveyor side on the mechanism of removing sections of mechanized sets are shown. The technique for determining this effort is presented. The constructions of the adaptive mechanisms of the removing sections of mechanized sets with the basements of catamaran type, in the constrictions of which elastic elements (rods) are used, are considered. The constructions of the mechanism of removing a section of the mechanized set with the basement of catamaran type in which the stock of the hydraulic jack is connected with the band loop through the movable rods intermediate basement with a link are worked out. The intermediate basement unloads the stock of the hydraulic jack of the moving installation from the side curving efforts, caused by the action of lateral forces in the plane of the seam on the conveyor side. It increases the reliability and efficiency of work of the knife plane mechanized complex.

  14. Testing model parameters for wave-induced dune erosion using observations from Hurricane Sandy

    Science.gov (United States)

    Overbeck, J. R.; Long, J. W.; Stockdon, H. F.

    2017-01-01

    Models of dune erosion depend on a set of assumptions that dictate the predicted evolution of dunes throughout the duration of a storm. Lidar observations made before and after Hurricane Sandy at over 800 profiles with diverse dune elevations, widths, and volumes are used to quantify specific dune erosion model parameters including the dune face slope, which controls dune avalanching, and the trajectory of the dune toe, which controls dune migration. Wave-impact models of dune erosion assume a vertical dune face and erosion of the dune toe along the foreshore beach slope. Observations presented here show that these assumptions are not always valid and require additional testing if these models are to be used to predict coastal vulnerability for decision-making purposes. Observed dune face slopes steepened by 43% yet did not become vertical faces, and only 50% of the dunes evolved along a trajectory similar to the foreshore beach slope. Observations also indicate that dune crests were lowered during dune erosion. Moreover, analysis showed a correspondence between dune lowering and narrower beaches, smaller dune volumes, and/or longer wave impact.

  15. Genetic parameters for test day somatic cell score in Brazilian Holstein cattle.

    Science.gov (United States)

    Costa, C N; Santos, G G; Cobuci, J A; Thompson, G; Carvalheira, J G V

    2015-12-29

    Selection for lower somatic cell count has been included in the breeding objectives of several countries in order to increase resistance to mastitis. Genetic parameters of somatic cell scores (SCS) were estimated from the first lactation test day records of Brazilian Holstein cows using random-regression models with Legendre polynomials (LP) of the order 3-5. Data consisted of 87,711 TD produced by 10,084 cows, sired by 619 bulls calved from 1993 to 2007. Heritability estimates varied from 0.06 to 0.14 and decreased from the beginning of the lactation up to 60 days in milk (DIM) and increased thereafter to the end of lactation. Genetic correlations between adjacent DIM were very high (>0.83) but decreased to negative values, obtained with LP of order four, between DIM in the extremes of lactation. Despite the favorable trend, genetic changes in SCS were not significant and did not differ among LP. There was little benefit of fitting an LP of an order >3 to model animal genetic and permanent environment effects for SCS. Estimates of variance components found in this study may be used for breeding value estimation for SCS and selection for mastitis resistance in Holstein cattle in Brazil.

  16. Testing of parameters of proposed robotic wrist based on the precision modules

    Directory of Open Access Journals (Sweden)

    Jan Semjon

    2016-10-01

    Full Text Available The use of precision actuators in robotic arm comes from the need to ensure the resulting accuracy of the robot at the maximum speed of movement. The replacement of actuators by means of electrical module allows the use of carrier body of the module for gripping flanges or other modules. Development of new modules is based on the requirement of providing a complete solution for the customer’s needs. After the development of new modules, the producer checks the parameters, receives feedback, and uses the authentication options in the independent workplaces, which can provide impartial results. Based on this data, manufacturers can optimize their solutions and deliver the products to market, complying with not only their vision but mainly the needs of customers. This article describes how to verify the characteristics of the modules used in the construction of robotic wrist. It primarily focuses on verification of the accuracy of results and repeatability of position of the wrist on output flange end module. In addition, it presents the design of the testing stand and selection methodologies of measurement. The declared values are compared with the values measured during verification.

  17. Wind tunnel tests of main girder with Π-shaped cross section

    Science.gov (United States)

    Guo, Junfeng; Hong, Chengjing; Zheng, Shixiong; Zhu, Jinbo

    2017-10-01

    The wind-resistant performance of a cable stayed bridge with IT-shaped girder was investigated by means of wind tunnel tests. Aerodynamic coefficients experiments and wind-induced vibration experiments with a sectional model a geometry scale of l to 60 were conducted. The results have shown that this kind of girder has the necessary condition for aerodynamic stability. Soft flutter of the main girder is a coupled two-degree-of-freedom torsional-bending vibration with single frequency. The amplitude of soft flutter follows a normal distribution, and the amplitude range varies with wind speed and angle of attack. The bridge deck auxiliary facilities can not only improve the critical soft flutter velocity, but also reduce the soft flutter amplitude and the amplitude growth rate.

  18. Velocimetry modalities for secondary flows in a curved artery test section

    Science.gov (United States)

    Bulusu, Kartik V.; Elkins, Christopher J.; Banko, Andrew J.; Plesniak, Michael W.; Eaton, John K.

    2014-11-01

    Secondary flow structures arise due to curvature-related centrifugal forces and pressure imbalances. These flow structures influence wall shear stress and alter blood particle residence times. Magnetic resonance velocimetry (MRV) and particle image velocimetry (PIV) techniques were implemented independently, under the same physiological inflow conditions (Womersley number = 4.2). A 180-degree curved artery test section with curvature ratio (1/7) was used as an idealized geometry for curved arteries. Newtonian blood analog fluids were used for both MRV and PIV experiments. The MRV-technique offers the advantage of three-dimensional velocity field acquisition without requiring optical access or flow markers. Phase-averaged, two-dimensional, PIV-data at certain cross-sectional planes and inflow phases were compared to phase-averaged MRV-data to facilitate the characterization of large-scale, Dean-type vortices. Coherent structures detection methods that included a novel wavelet decomposition-based approach to characterize these flow structures was applied to both PIV- and MRV-data. The overarching goal of this study is the detection of motific, three-dimensional shapes of secondary flow structures using MRV techniques with guidance obtained from high fidelity, 2D-PIV measurements. This material is based in part upon work supported by the National Science Foundation under Grant Number CBET-0828903, and GW Center for Biomimetics and Bioinspired Engineering (COBRE).

  19. Measurement of single-top cross section and test of anomalous $Wtb$ coupling

    Energy Technology Data Exchange (ETDEWEB)

    Jung, Ji-Eun [Seoul National Univ. (Korea, Republic of)

    2010-01-01

    The top quark is most often produced in tt pairs via the strong interaction, however electroweak production of a singly-produced top quark is also possible. Electroweak single-top production is more difficult to observe than tt production. Studying single-top production is important for the following reasons. It provides direct measurement of the CKM matrix element and also single-top events are a background to several searches for SM or non-SM signals, such as Higgs boson searches. The information of spin polarization of top-quark can be used to t est anomalous W-t-b coupling. This thesis describes the result of a measurement of single-top cross-section and a test of anomalous W-t-b coupling using 4.8 f b-1 of data collected by the CDF Run II experiment at the Fermilab Tevatron. The measured cross-section is 1.83$+0.7\\atop{-0.6}$ pb and measured limit of |Vtb| is 0.41 at 95% CL. The fraction of V+A coupling is 0 ± 28 (%).

  20. An analysis on the breeding capability and safety related parameters of advanced fast reactor fuels using recent cross-section set

    Energy Technology Data Exchange (ETDEWEB)

    Stephen, Neethu Hanna, E-mail: neethu83@igcar.gov.in; Reddy, C.P.

    2013-09-15

    Highlights: • Breeding ratio of fast reactor fuels is computed with latest cross-section set. • Safety related parameters are also evaluated. • It is found that there are better prospects of utilization of thorium resources. • With large fast reactors, Th–{sup 233}U fuel combination gives better B.G. -- Abstract: This study focuses on the evaluation of breeding capability as well as safety related neutronic parameters of advanced fast reactor fuels which comprises of fissile–fertile combination of metal, oxide, carbide and nitride, using the recent neutron cross-section set ENDF/B-VI.7. Sodium cooled fast breeder reactor similar to prototype Fast Breeder Reactor (PFBR) is used to evaluate the performance of various fuel types involving fissile isotopes of {sup 233}U and Pu and fertile isotopes of Th and {sup 238}U. The analysis is restricted to a comparison of neutronic parameters of a fresh core and does not take into account the effects of burnup and fission products. The breeding potential of the fuels are also compared with European cross-section set JEFF-3.1. The breeding ratio of advanced fuels evaluated with ENDF/B-VI.7 and JEFF-3.1 was found to be in good agreement. From this study, it is found that Th–{sup 233}U combination for almost all fuel types with the present geometry and composition gives a lower breeding ratio value. Safety neutronic parameters such as effective delayed neutron fraction, Doppler defect and sodium void reactivity were also computed. In terms of breeding potential and safety neutronic parameters, the performance of Th–Pu system especially the metal fuel type can be a better option for future large fast reactors. The large negative Doppler feedback along with a negative sodium void reactivity for metal and hybrid combinations of Th–{sup 233}U system makes it an attractive fuel cycle option even though there is a penalty over its breeding capability.

  1. Influence of test parameters on in vitro fracture resistance of post-endodontic restorations: a structured review.

    NARCIS (Netherlands)

    Naumann, M.; Metzdorf, G.; Fokkinga, W.A.; Watzke, R.; Sterzenbach, G.; Bayne, S.; Rosentritt, M.

    2009-01-01

    A structured literature review aimed to elucidate test parameters for in vitro testing of post-endodontic restorations. The literature was digitally searched using MEDLINE, EMBASE, MedPilot and an additional hand search was performed. Two independent researchers assessed the articles in relation to

  2. Risk Assessment of Hepatocellular Carcinoma in General Population by Liver Stiffness in Combination with Controlled Attenuation Parameter using Transient Elastography: A Cross Sectional Study.

    Science.gov (United States)

    Sugihara, Takaaki; Koda, Masahiko; Matono, Tomomitsu; Okamoto, Kinya; Murawaki, Yoshikazu; Isomoto, Hajime; Tokunaga, Shiho

    2017-06-01

    Hepatocellular carcinoma (HCC) in patients without hepatitis B (HBV) and -C virus (HCV) infection are increasing in Japan. Method for detecting high-risk liver diseases of HCC in general population has still not been established. Liver stiffness measurement (LSM) and Controlled Attenuation Parameter (CAP) using transient elastography (TE; FibroScan System) are useful for detecting liver fibrosis and steatosis. The aim of this study is to clarify TE for risk assessment of HCC in general population. This cross-sectional study was performed for residents aged ≥ 40 years in an intermountain town in Japan with a population of 3,493. Blood laboratory testing included tumor markers, abdominal ultrasound (AUS), and TE was performed. Among 175 subjects (64 men, 111 women), TE was evaluated and three patients with HCC were detected by AUS. For detecting HCC, the cut-off value of LSM was 5.3 kPa sensitivity 100%, specificity 75%, AUROC 0.88). The combination of LSM and CAP (LSM > 5.3 kPa with any CAP and CAP > 248 dB/m with any LSM) could detect the high-risk liver diseases of HCC (HCC, nonalcoholic fatty liver/steatohepatitis, HBV or HCV related chronic viral hepatitis with alanine transaminase (ALT) > 30 IU/L for men or > 19 IU/L for women or cirrhosis of any cause) with high sensitivity (sensitivity 90%, specificity 55%, positive predictive value 10%, negative predictive value 99%, P = 0.006). The combination of LSM and CAP can be useful in detecting high-risk liver diseases of HCC out of general population.

  3. The Impact of Escape Alternative Position Change in Multiple-Choice Test on the Psychometric Properties of a Test and Its Items Parameters

    Science.gov (United States)

    Hamadneh, Iyad Mohammed

    2015-01-01

    This study aimed at investigating the impact changing of escape alternative position in multiple-choice test on the psychometric properties of a test and it's items parameters (difficulty, discrimination & guessing), and estimation of examinee ability. To achieve the study objectives, a 4-alternative multiple choice type achievement test…

  4. 25-Hydroxyivitamin D3 levels in patients with systemic lupus erythematosus and its association with clinical parameters and laboratory tests.

    Science.gov (United States)

    Fragoso, Thiago Sotero; Dantas, Andrea Tavares; Marques, Claudia Diniz Lopes; Rocha Junior, Laurindo Ferreira da; Melo, José Humberto de Lima; Costa, Aline Jurema Gesteira; Duarte, Angela Luzia Branco Pinto

    2012-01-01

    The immunoregulatory role of vitamin D has been the object of a growing number of studies in patients with systemic lupus erythematosus (SLE). To determine the serum levels of 25-hydroxyvitamin D3 [25(OH) D] in patients with SLE, and to assess the association of 25(OH)D insufficiency/deficiency with clinical parameters and laboratory tests. Cross-sectional, prospective study performed at the SLE Clinic, Department of Rheumatology, Hospital das Clínicas, Universidade Federal de Pernambuco with convenience sampling, including 78 patients with SLE and 64 volunteers (comparison group), matched by gender and age. Insufficiency/deficiency of 25(OH)D was found in 45 (57.7%) patients with SLE and 25 (39%) individuals in the comparison group. The mean serum levels of 25(OH)D were 29.3 ng/mL (6.1-55.2 ng/mL) in patients with SLE and 33.12 ng/mL (15.9-63.8 ng/mL) in the comparison group, and this difference was statistically significant (P = 0.041). No statistically significant difference was observed between the mean ages of both groups. No statistically significant association was observed between 25(OH)D insufficiency/deficiency and the following: time to diagnosis; disease activity (SLEDAI > 6); fatigue; use of corticosteroids and antimalarials; and anti-DNA. High prevalence of 25(OH)D insufficiency/deficiency was found in patients with SLE (57.7%), with statistically significant difference as compared with the comparison group. No association of vitamin D insufficiency/deficiency was observed with the clinical variables and laboratory tests studied. The authors emphasize the importance of determining 25(OH)D serum levels in all patients with SLE, regardless of where they live and time to disease diagnosis.

  5. Pulmonary function tests in idiopathic inflammatory myopathy: association with clinical parameters in children.

    Science.gov (United States)

    Prestridge, Adrienne; Morgan, Gabrielle; Ferguson, Lori; Huang, Chiang-Ching; Pachman, Lauren M

    2013-09-01

    To determine the association of decreased lung function in children with idiopathic inflammatory myopathies (IIMs) with specific clinical parameters. This study of 38 children ages 6-23 years diagnosed with definite/probable IIM evaluated the association of myositis-specific/-associated antibodies (MSAs/MAAs), duration of untreated disease at diagnosis, Disease Activity Score for muscle (DAS-M), muscle-derived enzymes (aldolase, lactate dehydrogenase [LDH], aspartate transaminase, and creatine phosphokinase [CPK]), neopterin and von Willebrand factor antigen, and the Childhood Myositis Assessment Scale (CMAS) scores with data from pulmonary function testing (PFT). Impaired PFTs were defined as total lung capacity (TLC) or diffusing capacity for carbon monoxide (DLCO) of children (14 of 38) had either decreased TLC or decreased DLCO; 5% (2 of 38) had both. Children with decreased TLC alone (7 [18%] of 38) were older both at the time of PFT and diagnosis, had anti-Jo-1 and anti-Scl-70 antibody, and had elevated levels of CPK and neopterin. Children with decreased DLCO alone (5 [13%] of 38) had a shorter duration of untreated disease at diagnosis, had higher DAS-M and total DAS, were positive for anti-Ro and anti-PL-12, had increased LDH, and had elevated levels of neopterin and aldolase, with low CMAS scores for items 1, 3, 10, 11, and 14. Assessment of PFTs in children with IIMs should be considered, since more than one-third of patients were found to be impaired. The presence of MSAs/MAAs, an elevated serum neopterin level (mean ± SD 12.4 ± 9.6 nmoles/liter, normal value <10.5), older age at diagnosis, and shorter duration of untreated disease at diagnosis suggest the presence of potential lung pathology. Copyright © 2013 by the American College of Rheumatology.

  6. Tests of a linear model of visual-vestibular interaction using the technique of parameter estimation.

    Science.gov (United States)

    Das, V E; DiScenna, A O; Feltz, A; Yaniglos, S; Leigh, R J

    1998-03-01

    The goal of this study was to test whether a superposition model of smooth-pursuit and vestibuloocular reflex (VOR) eye movements could account for the stability of gaze that subjects show as they view a stationary target, during head rotations at frequencies that correspond to natural movements. Horizontal smooth-pursuit and the VOR were tested using sinusoidal stimuli with frequencies in the range 1.0-3.5 Hz. During head rotation, subjects viewed a stationary target either directly or through an optical device that required eye movements to be approximately twice the amplitude of head movements in order to maintain foveal vision of the target. The gain of compensatory eye movements during viewing through the optical device was generally greater than during direct viewing or during attempted fixation of the remembered target location in darkness. This suggests that visual factors influence the response, even at high frequencies of head rotation. During viewing through the optical device, the gain of compensatory eye movements declined as a function of the frequency of head rotation (P 0.23), peak head acceleration (P > 0.22) or retinal slip speed (P > 0.22). The optimal values of parameters of smooth-pursuit and VOR components of a simple superposition model were estimated in the frequency domain, using the measured responses during head rotation, as each subject viewed the stationary target through the optical device. We then compared the model's prediction of smooth-pursuit gain and phase, at each frequency, with values obtained experimentally. Each subject's pursuit showed lower gain and greater phase lag than the model predicted. Smooth-pursuit performance did not improve significantly if the moving target was a 10 deg x 10 deg Amsler grid, or if sinusoidal oscillation of the target was superimposed on ramp motion. Further, subjects were still able to modulate the gain of compensatory eye movements during pseudo-random head perturbations, making improved

  7. Photoionization using the xchem approach: Total and partial cross sections of Ne and resonance parameters above the 2 s22 p5 threshold

    Science.gov (United States)

    Marante, Carlos; Klinker, Markus; Kjellsson, Tor; Lindroth, Eva; González-Vázquez, Jesús; Argenti, Luca; Martín, Fernando

    2017-08-01

    The XCHEM approach interfaces well established quantum chemistry packages with scattering numerical methods in order to describe single-ionization processes in atoms and molecules. This should allow one to describe electron correlation in the continuum at the same level of accuracy as quantum chemistry methods do for bound states. Here we have applied this method to study multichannel photoionization of Ne in the vicinity of the autoionizing states lying between the 2 s22 p5 and 2 s 2 p6 ionization thresholds. The calculated total photoionization cross sections are in very good agreement with the absolute measurement of Samson et al. [J. Electron Spectrosc. Relat. Phenom. 123, 265 (2002), 10.1016/S0368-2048(02)00026-9], and with independent benchmark calculations performed at the same level of theory. From these cross sections, we have extracted resonance positions, total autoionization widths, Fano profile parameters, and correlation parameters for the lowest three autoionizing states. The values of these parameters are in good agreement with those reported in earlier theoretical and experimental work. We have also evaluated β asymmetry parameter and partial photoionization cross sections and, from the latter, partial autoionization widths and Starace parameters for the same resonances, not yet available in the literature. Resonant features in the calculated β parameter are in good agreement with the experimental observations. We have found that the three lowest resonances preferentially decay into the 2 p-1ɛ d continuum rather than into the 2 p-1ɛ s one [Phys. Rev. A 89, 043415 (2014), 10.1103/PhysRevA.89.043415], in agreement with previous expectations, and that in the vicinity of the resonances the partial 2 p-1ɛ s cross section can be larger than the 2 p-1ɛ d one, in contrast with the accepted idea that the latter should amply dominate in the whole energy range. These results show the potential of the XCHEM approach to describe highly correlated process

  8. Standard test method for determining the effective elastic parameter for X-ray diffraction measurements of residual stress

    CERN Document Server

    American Society for Testing and Materials. Philadelphia

    1998-01-01

    1.1 This test method covers a procedure for experimentally determining the effective elastic parameter, Eeff, for the evaluation of residual and applied stresses by X-ray diffraction techniques. The effective elastic parameter relates macroscopic stress to the strain measured in a particular crystallographic direction in polycrystalline samples. Eeff should not be confused with E, the modulus of elasticity. Rather, it is nominally equivalent to E/(1 + ν) for the particular crystallographic direction, where ν is Poisson's ratio. The effective elastic parameter is influenced by elastic anisotropy and preferred orientation of the sample material. 1.2 This test method is applicable to all X-ray diffraction instruments intended for measurements of macroscopic residual stress that use measurements of the positions of the diffraction peaks in the high back-reflection region to determine changes in lattice spacing. 1.3 This test method is applicable to all X-ray diffraction techniques for residual stress measurem...

  9. Von Willebrand factor and fibrinolytic parameters during the desmopressin test in patients with Cushing's disease

    Science.gov (United States)

    Giraldi, Francesca Pecori; Ambrogio, Alberto G; Fatti, Letizia M; Rubini, Valentina; Cozzi, Giovanna; Scacchi, Massimo; Federici, Augusto B; Cavagnini, Francesco

    2011-01-01

    AIMS Desmopressin, a vasopressin analogue, is used for various clinical purposes, including haemostasis and, in recent times, the diagnostic work-up of patients with Cushing's syndrome, a condition associated with a known prothrombotic profile. We decided to evaluate whether and to what extent a diagnostic dose of desmopressin induces significant changes in endothelial parameters in patients with Cushing's disease (CD) and obese and normal weight controls. METHODS Twelve patients with CD, 10 obese and five normal weight controls were studied. Von Willebrand antigen (VWF : Ag), tissue plasminogen activator (t-PA) and plasminogen activator inhibitor type 1 (PAI-1) were measured at baseline and up to 4 h after 10 µg desmopressin i.v. RESULTS Desmopressin 10 µg transiently increased VWF : Ag and t-PA and decreased PAI-1 in all subjects. The magnitude of the VWF : Ag and t-PA increases after desmopressin was comparable in the three groups (VWF : Ag peak-to-basal ratio 1.9 ± 0.17, 1.5 ± 0.11 and 1.8 ± 0.13 and t-PA peak-to-basal ratio 1.6 ± 0.18, 1.6 ± 0.20 and 1.8 ± 0.24 for CD, obese and controls, respectively, all NS). The PAI-1 decrease observed in patients with CD was comparable with obese (0.7 ± 0.07 and 0.6 ± 0.09, NS) and controls (0.7 ± 0.07 vs. 0.4 ± 0.09, P = 0.08). CONCLUSIONS Administration of desmopressin to patients with CD for diagnostic purposes induces a transitory increase in VWF : Ag counterbalanced by a decrease in PAI-1 and increase in t-PA. The magnitude of these changes is largely comparable with that observed in obese and normal weight controls. Our data show that testing with desmopressin does not induce disease-specific changes in endothelial markers in patients with CD. PMID:21143510

  10. Evaluation of bone mineral density and related parameters in patients with haemophilia: a single center cross-sectional study.

    Science.gov (United States)

    Kiper Unal, Hatice Demet; Comert Ozkan, Melda; Atilla, Fatos Dilan; Demirci, Zuhal; Soyer, Nur; Yildirim Simsir, Ilgin; Omur, Ozgur; Capaci, Kazim; Saydam, Guray; Sahin, Fahri

    2017-01-01

    Haemophilia has been associated with low bone mineral density (BMD) probably due to some predisposing factors. The aim of this study was to evaluate the relationship between BMD and potential clinical predictors in adult haemophilic patients. Fortynine patients with moderate and severe haemophilia were enrolled. BMD was measured by Dual Energy X-Ray Absorptiometry (DXA) and blood tests were performed for vitamin D, calcium, phosphore, alkaline phosphatase and parathormone levels. Functional Independence Score in Haemophilia (FISH) and Haemophilia Joint Health Score (HJHS) were used to assess musculoskeletal functions. Body mass index (BMI), Hepatitis C virus (HCV)/Human immunodeficiency virus (HIV) seropositivity and smoking status were also recorded. BMD was found lower than expected for reference age in 34.8% of patients of less than 50 years old. In patients older than 50 years, 66.6% of them had osteoporosis and 33.3% of them had normal BMD. FISH score was statistically significant correlated with BMD of total hip (TH) and femur neck (FN) but not with lumbar spine (LS). In eligible patients, there was also a statistically significant correlation between BMD of TH and HJHS. Vitamine D deficiency was common and found in 77.5% of patients, although there was no significant correlation with BMD. Also no correlation was found between BMD and blood tests, HCV/HIV status, BMI and smoking. This study confirmed that patients with haemophilia have an increased prevelance of low BMD even in younger group. Our results showed that there are significant correlations between FISH score and BMD of TH and FN and also between HJHS score and BMD of TH. Thus, using scoring systems may be beneficial as a simple predictors of BMD to reflect the severity of haemophilic arthropathy.

  11. [The influence of laser therapy on selected functional parameters of patients with spondyloarthrosis of the lower section of the spine].

    Science.gov (United States)

    Zdrodowska, Beata; Leszczyńska-Filus, Magdalena; Leszczyński, Ryszard; Błaszczyk, Jan

    2014-02-01

    Spondyloarthrosis is a quickly growing disease in highly civilized communities. It is one of the most frequent causes for movement limitations and is listed as the main reason for the incapacitation for work among people of the working age. The following symptoms can be observed in patients with spondyloarthrosis: pain, limited spine mobility, increased muscle tone. Chronic pain and the associated limitation of movement underlie the quest for an effective therapy. Using laser therapy as part of physical therapy prompts research into the effectiveness of the measure in patients with spondyloarthrosis. The aim of this study was to evaluate the effectiveness of laser therapy on spondyloarthrosis of the lumbar spine. 60 patients suffering from chronic low back pain, diagnosed with a lumbar disc herniation with no nerve root symptoms, received laser therapy (820 nm, 400 mW, 6-12 J/cm2. Every patient underwent examinations before and after rehabilitation. Subjective pain assessment was carried out using a modified Laitinen questionnaire and visual analogue scale of pain intensity. Spine mobility was evaluated using Schober's test and the fingertip-to-floor-test. The obtained results were subject to a statistical analysis. Laser therapy was effective in the therapy of lumbar disc herniation. The results of the analysis showed that the intensity and frequency of pain decreased, as well as the use of painkillers. A vast improvement in global spine mobility and lumbosacral flexion and extension could be observed, too. The study showed a slight analgesic effect and a substantial increase in spine mobility through laser biostimulation.

  12. Selective reporting of antibiotic susceptibility test results in European countries: an ESCMID cross-sectional survey.

    Science.gov (United States)

    Pulcini, Céline; Tebano, Gianpiero; Mutters, Nico T; Tacconelli, Evelina; Cambau, Emmanuelle; Kahlmeter, Gunnar; Jarlier, Vincent

    2017-02-01

    Selective reporting of antibiotic susceptibility test (AST) results is one possible laboratory-based antibiotic stewardship intervention. The primary aim of this study was to identify where and how selective reporting of AST results is implemented in Europe both in inpatient and in outpatient settings. An ESCMID cross-sectional, self-administered, internet-based survey was conducted among all EUCIC (European Committee on Infection Control) or EUCAST (European Committee on Antimicrobial Susceptibility Testing) national representatives in Europe and Israel. Of 38 countries, 36 chose to participate in the survey. Selective reporting of AST results was implemented in 11/36 countries (31%), was partially implemented in 4/36 (11%) and was limited to local initiatives or was not adopted in 21/36 (58%). It was endorsed as standard of care by health authorities in only three countries. The organisation of selective reporting was everywhere discretionally managed by each laboratory, with a pronounced intra- and inter-country variability. The most frequent application was in uncomplicated community-acquired infections, particularly urinary tract and skin and soft-tissue infections. The list of reported antibiotics ranged from a few first-line options, to longer reports where only last-resort antibiotics were hidden. Several barriers to implementation were reported, mainly lack of guidelines, poor system support, insufficient resources, and lack of professionals' capability. In conclusion, selective reporting of AST results is poorly implemented in Europe and is applied with a huge heterogeneity of practices. Development of an international framework, based on existing initiatives and identified barriers, could favour its dissemination as one important element of antibiotic stewardship programmes. Copyright © 2017 Elsevier B.V. and International Society of Chemotherapy. All rights reserved.

  13. Testing an ionization chamber with gaseous samples and measurements of the (n, alpha) reaction cross sections

    CERN Document Server

    Gledenov, Yu M; Salatskii, V I; Sedyshev, P V; Andrzejewski, J; Szalanski, P

    1999-01-01

    A new ionization chamber with gaseous samples (GIC) has been designed and tested on the thermal and resonance neutron beams of FLNP's neutron sources. The exposed gas volume serves as a target for neutrons. The obtained thermal cross sections for the sup 1 sup 7 O(n, alpha) sup 1 sup 4 C, sup 2 sup 1 Ne(n, alpha) sup 1 sup 8 O and sup 3 sup 6 Ar(n, alpha) sup 3 sup 3 S reactions are (233+-12) mb, (0.18+-0.09) mb and (5.43+-0.27) mb, respectively. These measurements have been performed on a pure beam of thermal neutrons from the high flux reactor IBR-2; and they demonstrated high efficiency and reliability of the method. Compared to samples on substrates, the application of gaseous samples makes the beam background essentially lower, and what is more important, the background component is totally absent due to the absence of Li and B microimpurities in gaseous samples while they do present in the samples on substrates. The method is also applicable to measurements with resonance neutrons. The recovery capabili...

  14. A cross-sectional testing of The Iowa Personality Disorder Screen in a psychiatric outpatient setting

    Directory of Open Access Journals (Sweden)

    Sørebø Øystein

    2011-06-01

    Full Text Available Abstract Background Patients suspected of personality disorders (PDs by general practitioners are frequently referred to psychiatric outpatient clinics (POCs. In that setting an effective screening instrument for PDs would be helpful due to resource constraints. This study evaluates the properties of The Iowa Personality Disorder Screen (IPDS as a screening instrument for PDs at a POC. Methods In a cross-sectional design 145 patients filled in the IPDS and were examined with the SCID-II interview as reference. Various case-findings properties were tested, interference of socio-demographic and other psychopathology were investigated by logistic regression and relationships of the IPDS and the concept of PDs were studied by a latent variable path analysis. Results We found that socio-demographic and psychopathological factors hardly disturbed the IPDS as screening instrument. With a cut-off ≥4 the 11 items IPDS version had sensitivity 0.77 and specificity 0.71. A brief 5 items version showed sensitivity 0.82 and specificity 0.74 with cut-off ≥ 2. With exception for one item, the IPDS variables loaded adequately on their respective first order variables, and the five first order variables loaded in general adequately on their second order variable. Conclusion Our results support the IPDS as a useful screening instrument for PDs present or absent in the POC setting.

  15. DEVELOPMENT OF THE MUNICIPAL NOISE-ABSORBING SCREEN AND TEST SECTION CONSTRUCTION TECHNOLOGY

    Directory of Open Access Journals (Sweden)

    Ondřej Bret

    2017-08-01

    Full Text Available The article presents the development and construction technology of the Municipal noise-absorbing screen (MNAS – in Czech "Mestská protihluková clona" (MPHC. The Municipal noise-absorbing screen is a new acoustical element developed in cooperation of the Department of Railway Structures, Faculty of Civil Engineering, CTU in Prague and the Montstav CZ s.r.o. Company. It is characterised by very small dimensions – its height is only ca 0.3 metre above the top of rail. The element serves to attenuate the noise induced by rail traffic arising at the wheel-rail contact. The Municipal noise-absorbing screen consists of individual, mutually interlocked units, placed one after another, made of bound recycled rubber. The article describes the major limiting conditions for the placement, shape and execution of the Municipal noise-absorbing screen. It also describes the construction of the test section situated on a tram track in Prague and sums up the experience obtained after the first year of operation.

  16. The Correlation Between the Six Minute Walk Test and Spirometric Parameters in Patients with Systemic Lupus Erythematosus

    Directory of Open Access Journals (Sweden)

    Zahra Mirfeizi

    2015-11-01

    Full Text Available Introduction: Systemic Lupus Erythematosus (SLE is an autoimmune disease affect nearly every organ system. Pulmonary involvement, which is a common manifestation of SLE, can remain undiagnosed if asymptomatic. This study aimed to evaluate the efficiency of spirometric findings in early detection of silent pulmonary involvement and examine its correlation with the six minute walk test in SLE patients. Materials and Methods: In this cross-sectional study fifty patients, who met the American College of Rheumatology criteria for SLE, were recruited from the outpatient rheumatology clinic at the Imam Reza Hospital of Mashhad between July 2013 and September 2014. First, a checklist including demographic information and previous medical documents was completed. Then, spirometry and 6MWT was performed to evaluate subclinical pulmonary involvement and assess patients’ exercise capacity. Results: Based on the results of pulmonary function tests, patients were divided into two groups. A total of 40 patients with normal pattern were placed in one group and 10 patients with restrictive pattern in the other. The difference between SLE patients with and without abnormal spirometry were statistically significant in regard to anti-RNP positivity but total distance walked in six minute, was not significantly different between two groups (p=0.356. Additionally, there were no significant correlations between 6MWD and FVC in SLE patients in the either group as determined by Pearson’s correlation coefficient testing. (R=0.439,P=0.205 in SLE patients with normal spirometry and R=0.191,P=0.237 in those with abnormal pattern Conclusion: Considering the impact of anti-U1RNP positivity with restrictive pattern on spirometry, it can be deemed as a pulmonary involvement predictor in SLE patients. However, lack of correlation between 6MWT and spirometric parameters is suggestive of restrictive lung involvement, which in turn, demonstrates a multifactorial basis for

  17. Review and test of methods for determination of the Schottky diode parameters

    Science.gov (United States)

    Olikh, O. Ya.

    2015-07-01

    This paper deals with the extraction of the Schottky diode parameters from a current-voltage characteristic. 10 analytical methods, 2 numerical methods, and 4 evolutionary algorithms of the series resistance, barrier height, and ideality factor determination are reviewed. The accuracy of the methods is quantified using a wide range of both ideal and noisy synthetic data. In addition, the influencing factors of the parameters extraction accuracy are estimated. The adaptive procedure, which improves the precision of analytical Gromov's method, is suggested. The use of Lambert W function has been shown to reduce the error of parameter extraction by numerical method. Finally, all methods are applied to experimental data. The most reliable and preferred methods are chosen.

  18. Development of a Quadrotor Test Bed — Modelling, Parameter Identification, Controller Design and Trajectory Generation

    National Research Council Canada - National Science Library

    Dong, Wei; Gu, Guo-Ying; Zhu, Xiangyang; Ding, Han

    2015-01-01

    In this paper, a quadrotor test bed is developed. The technical approach for this test bed is firstly proposed by utilizing a commercial quadrotor, a Vicon motion capture system and a ground station...

  19. Relation of thromboelastography parameters to conventional coagulation tests used to evaluate the hypercoagulable state of aged fracture patients

    Science.gov (United States)

    Liu, Chen; Guan, Zhao; Xu, Qinzhu; Zhao, Lei; Song, Ying; Wang, Hui

    2016-01-01

    Abstract Fractures are common among aged people, and rapid assessment of the coagulation status is important. The thromboelastography (TEG) test can give a series of coagulation parameters and has been widely used in clinics. In this research, we looked at fracture patients over 60 and compared their TEG results with those of healthy controls. Since there is a paucity of studies comparing TEG assessments with conventional coagulation tests, we aim to clarify the relationship between TEG values and the values given by conventional coagulation tests. Forty fracture patients (27 femur and 13 humerus) over 60 years old were included in the study. The change in their coagulation status was evaluated by TEG before surgery within 4 hours after the fracture. Changes in TEG parameters were analyzed compared with controls. Conventional coagulation test results for the patients, including activated partial thromboplastin time (APTT), international normalized ratio (INR), fibrinogen, and platelets, were also acquired, and correlation analysis was done with TEG parameters, measuring similar aspects of the coagulation cascade. In addition, the sensitivity and specificity of TEG parameters for detecting raised fibrinogen levels were also analyzed. The K (time to 20 mm clot amplitude) and R (reaction time) values of aged fracture patients were lower than controls. The values for angle, maximal amplitude (MA), and coagulation index (CI) were raised compared with controls, indicating a hypercoagulable state. Correlation analysis showed that there were significant positive correlations between fibrinogen and MA/angle, between platelets and MA, and between APTT and R as well. There was significant negative correlation between fibrinogen and K. In addition, K values have better sensitivity and specificity for detecting elevated fibrinogen concentration than angle and MA values. Aged fracture patients tend to be in a hypercoagulable state, and this could be effectively reflected by

  20. Robust Automated Test Assembly for Testlet-Based Tests: An Illustration With the Analytical Reasoning Section of the LSAT

    NARCIS (Netherlands)

    Veldkamp, Bernard P.; Paap, Muirne

    2013-01-01

    In many high-stakes tests, subsets of questions (i.e., items) grouped around a common stimulus are often utilized to increase testing efficiency. These subsets of items are commonly called testlets. Since responses to items belonging to the same testlet not only depend on the test taker’s ability,

  1. A Comparison of the One-and Three-Parameter Logistic Models on Measures of Test Efficiency.

    Science.gov (United States)

    Benson, Jeri

    Two methods of item selection were used to select sets of 40 items from a 50-item verbal analogies test, and the resulting item sets were compared for relative efficiency. The BICAL program was used to select the 40 items having the best mean square fit to the one parameter logistic (Rasch) model. The LOGIST program was used to select the 40 items…

  2. The impact of parameter estimation on computerized adaptive testing with item cloning

    NARCIS (Netherlands)

    Glas, Cornelis A.W.

    Item cloning techniques can greatly reduce the cost of item writing and enhance the flexibility of item presentation. An important consequence of cloning is that it may cause variability in the item parameters. Recently, Glas and van der Linden (in press, 2005) proposed a multilevel item response

  3. Crash Simulation of a Vertical Drop Test of a B737 Fuselage Section with Overhead Bins and Luggage

    Science.gov (United States)

    Jackson, Karen E.; Fasanella, Edwin L.

    2004-01-01

    The focus of this paper is to describe a crash simulation of a 30-ft/s vertical drop test of a Boeing 737 (B737) fuselage section. The drop test of the 10-ft. long fuselage section of a B737 aircraft was conducted in November of 2000 at the FAA Technical Center in Atlantic City, NJ. The fuselage section was outfitted with two different commercial overhead stowage bins. In addition, 3,229-lbs. of luggage were packed in the cargo hold to represent a maximum take-off weight condition. The main objective of the test was to evaluate the response and failure modes of the overhead stowage bins in a narrow-body transport fuselage section when subjected to a severe, but survivable, impact. A secondary objective of the test was to generate experimental data for correlation with the crash simulation. A full-scale 3-dimensional finite element model of the fuselage section was developed and a crash simulation was conducted using the explicit, nonlinear transient dynamic code, MSC.Dytran. Pre-test predictions of the fuselage and overhead bin responses were generated for correlation with the drop test data. A description of the finite element model and an assessment of the analytical/experimental correlation are presented. In addition, suggestions for modifications to the model to improve correlation are proposed.

  4. Illness perception is a strong parameter on anxiety and depression scores in early-stage breast cancer survivors: a single-center cross-sectional study of Turkish patients.

    Science.gov (United States)

    Kus, Tulay; Aktas, Gokmen; Ekici, Hatice; Elboga, Gulcin; Djamgoz, Sabire

    2017-11-01

    Illness perception has been suggested to have a significant effect on anxiety and depression in cancer patients. In this cross-sectional study, we aimed to evaluate this on Turkish breast cancer patients with follow-up periods up to 12 years. A total of 225 patients (with 6 months to 12 years follow-up) were recruited in this cross-sectional study. The patients were divided into three groups of follow-up: 6 months-2 years, 2-5 years, and >5 years. Beck Depression Inventory, Beck Anxiety Inventory, Duke-University of North Carolina Functional Social Support Questionnaire, and Brief Illness Perception Questionnaire were used to assess the depression, anxiety, functional social support (FSS), and illness perception, respectively. Statistical significance of the associations was analyzed using Spearman correlation, Student's t, Mann-Whitney U, and ANOVA tests. Rates of moderate-severe anxiety and depression scores were not correlated with follow-up period and disease stage, whereas all these parameters were associated significantly with FSS and age. Parameters of illness perception were also not correlated with follow-up period and stage of disease. However, illness perception scores were noticeably better with increments in FSS. Also, the parameters of illness perception were strongly associated with the depression/anxiety score. Illness perception is an important determinant of the depression/anxiety score in Turkish breast cancer patients.

  5. Estimation of genetic parameters for test-day milk production at different stages of lactation of Finnish Ayrshire heifers

    Directory of Open Access Journals (Sweden)

    A. KETTUNEN

    2008-12-01

    Full Text Available Genetic parameters for test-day milk production at different stages of lactation of Finnish Ayrshire heifers were estimated with the REML method using the AI algorithm and animal model. The data consisted of 38679 first lactation test-day milk yields of 4205 cows from 231 herds in three geographical regions (North Savo, Central Ostrobothnia and Lapland. To identify different test days, records were numbered according to the days in milk after calving, and were further categorized into three part-lactations according to the test-day classification. Expressions in the three part-lactations were considered as separate traits, and tests were treated as repeated observations within the trait. Heritability estimates for test-day milk yield varied between 0. 11 and 0. 17, being lowest at the beginning of lactation. Genetic correlations between test-day milk yields at different trimesters ranged from 0.64 to 0.91, being highest between consecutive trimesters. Standard errors of the estimates of genetic parameters varied between 0.02 and 0.08. Genetic interrelationships differed from 1.0, supporting the assumption that genetic variation exists in the shape of the lactation curve. The necessity of considering deviations from the general lactation curve in the test-day model, e.g. fitting random regression coefficients, is discussed.;

  6. An empirical examination of the generalized Fisher effect using cross-sectional correlation robust tests for panel cointegration

    OpenAIRE

    Omay, Tolga; Yüksel, Aslı; Yüksel, Sadettin Aydın

    2015-01-01

    This study examines the generalized Fisher hypothesis as applied to common stocks by using the recently proposed second generation panel cointegration tests. Unlike their predecessors, these new tests assume the existence of cross-section dependence in the data. For the sample analyzed, we report that these new tests, but not their predecessors, provide strong support for the existence of cointegration between stock and goods prices. Moreover, further analysis cannot reject the hypothesis tha...

  7. Aerodynamic Parameters of High Performance Aircraft Estimated from Wind Tunnel and Flight Test Data

    Science.gov (United States)

    Klein, Vladislav; Murphy, Patrick C.

    1998-01-01

    A concept of system identification applied to high performance aircraft is introduced followed by a discussion on the identification methodology. Special emphasis is given to model postulation using time invariant and time dependent aerodynamic parameters, model structure determination and parameter estimation using ordinary least squares an mixed estimation methods, At the same time problems of data collinearity detection and its assessment are discussed. These parts of methodology are demonstrated in examples using flight data of the X-29A and X-31A aircraft. In the third example wind tunnel oscillatory data of the F-16XL model are used. A strong dependence of these data on frequency led to the development of models with unsteady aerodynamic terms in the form of indicial functions. The paper is completed by concluding remarks.

  8. Parameter Estimation of Viscoelastic Materials: A Test Case with Different Optimization Strategies

    Science.gov (United States)

    Fernanda, M.; Costa, P.; Ribeiro, C.

    2011-09-01

    In this work, and based on numerical optimization techniques, constitutive parameters for viscoelastic materials are determined using a inverse problem formulation. The optimization methodology is based on experimental results obtained in the frequency domain, for a CFRP-Carbon Fibre Reinforced Polymer, through DMA-Dynamic Mechanical Analysis. The relaxation modulus of viscoelastic materials is given by a summation of decaying exponentiating functions, known as Prony series. Prony series, in time domain, are normally used to determine constitutive parameters for viscoelastic materials. In this paper, using the Fourier transform of the time domain Prony series, a nonlinear constrained least square problem based on Prony series representations of storage and loss modulus, for the considered material, is analyzed. A case study considering the estimation of 2N viscoelastic parameters, N = 1,2,⋯11, is taken as a benchmark. The nonlinear constrained least square problems are solved using global and local optimization solvers. The computational results as well as the main conclusion are shown.

  9. Biological and analytical variations of 16 parameters related to coagulation screening tests and the activity of coagulation factors.

    Science.gov (United States)

    Chen, Qian; Shou, Weiling; Wu, Wei; Guo, Ye; Zhang, Yujuan; Huang, Chunmei; Cui, Wei

    2015-04-01

    To accurately estimate longitudinal changes in individuals, it is important to take into consideration the biological variability of the measurement. The few studies available on the biological variations of coagulation parameters are mostly outdated. We confirmed the published results using modern, fully automated methods. Furthermore, we added data for additional coagulation parameters. At 8:00 am, 12:00 pm, and 4:00 pm on days 1, 3, and 5, venous blood was collected from 31 healthy volunteers. A total of 16 parameters related to coagulation screening tests as well as the activity of coagulation factors were analyzed; these included prothrombin time, fibrinogen (Fbg), activated partial thromboplastin time, thrombin time, international normalized ratio, prothrombin time activity, activated partial thromboplastin time ratio, fibrin(-ogen) degradation products, as well as the activity of factor II, factor V, factor VII, factor VIII, factor IX, and factor X. All intraindividual coefficients of variation (CVI) values for the parameters of the screening tests (except Fbg) were less than 5%. Conversely, the CVI values for the activity of coagulation factors were all greater than 5%. In addition, we calculated the reference change value to determine whether a significant difference exists between two test results from the same individual. Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

  10. Tectonic Signals Deduced from Quantitative Analysis of Geomorphic Parameters in Bedrock Rivers and Structural Mapping: A case study from the Surai Khola Siwalik Section, Nepalese Himalaya

    Science.gov (United States)

    Bhattarai, I.; Gani, N. D.

    2016-12-01

    The Nepalese Himalaya is one of the most active regions within the Himalayan Mountain Belt, which is characterized by a thick succession of Siwalik sedimentary rocks deposited at its foreland basin. To date, much of the tectonic geomorphologic study in the Nepalese Siwalik is poorly understood, particularly in the Surai Khola section. Thus, the study of quantitative analysis of bedrock river parameters will provide crucial information regarding tectonic activities in the area. This study investigates geomorphic parameters of longitudinal river profiles from 54 watersheds within the Siwalik section of the Nepalese Himalaya. We extracted a total of 140 bedrock rivers from these watersheds using stream power-law function and 30-meter resolution ASTER DEM. In addition, we used 90-meter resolution SRTM DEM for structural mapping within the Surai Khola section. Our new results show presence of major and minor knickpoints that were classified on the basis of relief of the longitudinal profiles. We identified 180 major knickpoints out of 305 total knickpoints. Normalized steepness index (ksn) and concavity index values vary above and below these knicpoints. The ksn values range from 5.3 to 140.6 while concavity index of the streams in the study area ranges from as low as -12.1 to as high as 31.1. We also identified a total of 133 structural lineations that were mapped for the first time using various sun illumination angles and azimuths, and slope. Most of these structural lineations are likely faults that follow the similar east-west trends of the Main Frontal Thrust (MFT) Fault. The length of these faults ranges from 0.5 km to 8 km. We interpreted that a few measured knickpoints might be associated with our mapped mesoscale faults, while the majority of the knickpoints in the river profiles are locally adjusting to the MFT related uplift.

  11. Estimation of the parameters of quality control test of professional competence of staff

    Directory of Open Access Journals (Sweden)

    Oleksandra Bakanova

    2015-06-01

    Full Text Available Purpose: to develop a method for estimating the reliability of the control of functional competencies of staff with limited test sample. Material and Methods: statistical process control, sampling by attributes. Results: the dependence of the reliability of the sampling of the sample size and the population of test questions, the control plan, methodical error sampling with a given probability. Conclusions: the proposed method of selecting control plan that allows correct (with a given probability decision criterion to choose the implementation of process control professional competencies of staff with limited test sample.

  12. Evaluation of the COPD Assessment Test and GOLD patient types: a cross-sectional analysis

    Directory of Open Access Journals (Sweden)

    Lopez-Campos JL

    2015-05-01

    Full Text Available Jose Luis Lopez-Campos,1,2,* Alberto Fernandez-Villar,3,* Carmen Calero-Acuña,1 Cristina Represas-Represas,3 Cecilia Lopez-Ramírez,1 Virginia Leiro Fernández,3 Juan Jose Soler-Cataluña,2,4 Ricard Casamor5 On behalf of the On-Sint study group 1Unidad Médico-Quirúrgica de Enfermedades Respiratorias, Instituto de Biomedicina de Sevilla (IBiS, Hospital Universitario Virgen del Rocio/Universidad de Sevilla, Sevilla, Spain; 2CIBER de Enfermedades Respiratorias (CIBERES, Instituto de Salud Carlos III, Madrid, Spain; 3Servicio de Neumología, Instituto de Investigación Biomédica de Vigo (IBIV, Complexo Hospitalario de Vigo, Vigo, Spain; 4Servicio de Neumología Hospital Arnau de Vilanova, Valencia, Spain; 5Departamento Médico de Novartis Farmacéutica, Barcelona, Spain *These authors contributed equally to this work Background: The COPD Assessment Test (CAT has been recently developed to quantify COPD impact in routine practice. However, no relationship with other measures in the Global Initiative for Obstructive Lung Disease (GOLD strategy has been evaluated. The present study aimed to evaluate the relationship of the CAT with other GOLD multidimensional axes, patient types, and the number of comorbidities.Methods: This was a cross-sectional analysis of the Clinical presentation, diagnosis, and course of chronic obstructive pulmonary disease (On-Sint study. The CAT score was administered to all participants at the inclusion visit. A GOLD 2011 strategy consisting of modified Medical Research Council scale (MRC scores was devised to study the relationship between the CAT, and GOLD 2011 axes and patient types. The relationship with comorbidities was assessed using the Charlson comorbidity index, grouped as zero, one to two, and three or more.Results: The CAT questionnaire was completed by 1,212 patients with COPD. The CAT maintained a relationship with all the three axes, with a ceiling effect for dyspnea and no distinction between mild and

  13. Dynamics of heart rate parameters in students with various personal anxiety levels during computerized testing.

    Science.gov (United States)

    Dzhebrailova, T D; Sulejmanova, R G

    2012-09-01

    Students with low level of initial (pre-test) personal anxiety demonstrated a high level of modulating effects on the heart rate in all basic frequency ranges (VLF, LF, and HF) resulting in a greater total power of heart rate variability spectrum compared to students with high personal anxiety. The peculiarities of dynamics of heart rate variability were revealed during a real learning task, which correlated with personal anxiety level. In comparison with highly anxious students, the low-anxious group demonstrated more pronounced drop in the power of all ranges of the heart rate variability spectrum during testing followed by restoration of these power indices to initial levels after completion of the test. In contrast, the drop of the total power of the heart rate variability spectrum and in the power of its individual components persisted in students with high anxiety level even after the end of the testing.

  14. Implementation of a multi-parameter Point-of-Care-blood test analyzer reduces central laboratory testing and need for blood transfusions in very low birth weight infants.

    Science.gov (United States)

    Mahieu, Ludo; Marien, Annick; De Dooy, Jozef; Mahieu, Margo; Mahieu, Hanne; Van Hoof, Viviane

    2012-01-18

    Blood sampling for laboratory testing is a major cause of iatrogenic blood loss and anemia in neonatal intensive care unit [NICU] patients. The objective of the study was to assess whether the implementation of a multi-parameter Point of Care Test [POCT] (Roche, Cobas b221) analyzer affected blood loss for central laboratory testing and need for red blood cell transfusion in our NICU. This was a retrospective observational cohort study in a NICU with comparison of two serial cohorts of 2 years each. Implementation of a multi-parameter POCT decreased central laboratory performed testing for bilirubin (-32% per patient) and electrolytes (-36% per patient). On average, the net blood volume taken per admitted patient for electrolyte testing decreased with 23.7% and 22.2% for bilirubin testing in the second cohort. After implementation of POCT, fewer very low birth weight infants [VLBWI] required blood transfusion (38.9% vs. 50%, pparameter POCT analyzer decreases transfusions among VLBWI by reducing iatrogenic blood loss for central laboratory testing. Copyright © 2011. Published by Elsevier B.V.

  15. Estimation of the parameters of quality control test of professional competence of staff

    OpenAIRE

    Oleksandra Bakanova; Andriy Yegorov; Tetiana Zakhvatova; Klavdiia Nekrasova

    2015-01-01

    Purpose: to develop a method for estimating the reliability of the control of functional competencies of staff with limited test sample. Material and Methods: statistical process control, sampling by attributes. Results: the dependence of the reliability of the sampling of the sample size and the population of test questions, the control plan, methodical error sampling with a given probability. Conclusions: the proposed method of selecting control plan that allows correct (with a given probab...

  16. Treated wastewater phytotoxicity assessment using Lactuca sativa: Focus on germination and root elongation test parameters.

    Science.gov (United States)

    Priac, Anne; Badot, Pierre-Marie; Crini, Grégorio

    2017-03-01

    Sensitive and simple ecotoxicological bioassays like seed germination and root elongation tests are commonly used to evaluate the phytotoxicity of waste and industrial discharge waters. Although the tests are performed following national and international standards, various parameters such as the number of seeds per dish, the test duration or the type of support used remain variable. To be able to make a correct comparison of results from different studies, it is crucial to know which parameter(s) could affect ecotoxicological diagnosis. We tested four different control waters and three seed densities. No significant differences on either germination rate or root elongation endpoints were shown. Nevertheless, we found that the four lettuce cultivars (Appia, batavia dorée de printemps, grosse blonde paresseuse, and Kinemontepas) showed significantly different responses when watered with the same and different metal-loaded industrial discharge water. From the comparison, it is clear that a differential sensitivity scale occurs among not just species but cultivars. Copyright © 2017 Académie des sciences. Published by Elsevier Masson SAS. All rights reserved.

  17. THE EFFICACY OF ANGLE-MATCHED ISOKINETIC KNEE FLEXOR AND EXTENSOR STRENGTH PARAMETERS IN PREDICTING AGILITY TEST PERFORMANCE.

    Science.gov (United States)

    Greig, Matt; Naylor, James

    2017-10-01

    Agility is a fundamental performance element in many sports, but poses a high risk of injury. Hierarchical modelling has shown that eccentric hamstring strength is the primary determinant of agility performance. The purpose of this study was to investigate the relationship between knee flexor and extensor strength parameters and a battery of agility tests. Controlled laboratory study. Nineteen recreational intermittent games players completed an agility battery and isokinetic testing of the eccentric knee flexors (eccH) and concentric knee extensors (conQ) at 60, 180 and 300°·s -1 . Peak torque and the angle at which peak torque occurred were calculated for eccH and conQ at each speed. Dynamic control ratios (eccH:conQ) and fast:slow ratios (300:60) were calculated using peak torque values, and again using angle-matched data, for eccH and conQ. The agility test battery differentiated linear vs directional changes and prescriptive vs reactive tasks. Linear regression showed that eccH parameters were generally a better predictor of agility performance than conQ parameters. Stepwise regression showed that only angle-matched strength ratios contributed to the prediction of each agility test. Trdaitionally calculated strength ratios using peak torque values failed to predict performance. Angle-matched strength parameters were able to account for 80% of the variation in T-test performance, 70% of deceleration distance, 55% of 10m sprint performance, and 44% of reactive change of direction speed. Traditionally calculated strength ratios failed to predict agility performance, whereas angle-matched strength ratios had better predictive ability and featured in a predictive stepwise model for each agility task. 2c.

  18. Development of base pressure similarity parameters for application to space shuttle launch vehicle power-on aerodynamic testing

    Science.gov (United States)

    Sulyma, P. R.; Penny, M. M.

    1978-01-01

    A base pressure data correlation study was conducted to define exhaust plume similarity parameters for use in Space Shuttle power-on launch vehicle aerodynamic test programs. Data correlations were performed for single bodies having, respectively, single and triple nozzle configurations and for a triple body configuration with single nozzles on each of the outside bodies. Base pressure similarity parameters were found to differ for the single nozzle and triple nozzle configurations. However, the correlation parameter for each was found to be a strong function of the nozzle exit momentum. Results of the data base evaluation are presented indicating an assessment of all data points. Analytical/experimental data comparisons were made for nozzle calibrations and correction factors derived, where indicated for use in nozzle exit plane data calculations.

  19. An improved model and parameters extraction for photovoltaic cells using only three state points at standard test condition

    Science.gov (United States)

    Peng, Lele; Sun, Yize; Meng, Zhuo

    2014-02-01

    In this paper, a comprehensive modeling and parameters extraction method is proposed to describe the current-voltage and power-voltage characteristic of photovoltaic cells. This method is based on data commonly issued by commercial photovoltaic data sheet. By using Lambert W function, the improved model of solar cells is given. Meanwhile, the current-voltage and power-voltage curves of photovoltaic cells are calculated. To extract the model parameters from only three state points at standard test conditions, an optimized approach using iterative method and approximate method is presented. Compared to the popular Rp model and experimental data, the proposed method shows excellent agreement between the current-voltages points. It is found that the proposed modeling and parameters extraction method has less error at the maximum power point state. Moreover, the proposed model is more realistic when subjected to ideality factors variations.

  20. Factors Affecting Result in Chinese Proficiency Test (HSK Level 6: Reading Section and Preparation Strategies

    Directory of Open Access Journals (Sweden)

    Sri Haryanti

    2013-11-01

    Full Text Available Chinese Proficiency Test (HSK is an internationally standardized exam which tests and rates Chinese language proficiency. The highest level in this test is level 6. The writing part of the test consists of 3 (three parts, namely, (1 listening, (2 reading, (3 writing. Furthermore, the reading part is made of 4 components. Level 6 of this test implies a high degree of difficulty. This paper specifically looked on how to prepare effectively for participants to be able to work on the reading part in order to achieve best result. This article used the methods of literature review and observational study as well as field research and would also incorporate the author’s personal experience in taking the test into recommending strategies for doing the reading part in a level 6 HSK test. Finally, research suggested several techniques and tips that might assist participants in achieving maximum scores in handling the reading part of level 6 HSK test.

  1. Serum parameters in the spectrum of coeliac disease: beyond standard antibody testing - a cohort study

    Directory of Open Access Journals (Sweden)

    Tack Greetje J

    2012-11-01

    Full Text Available Abstract Background Invasive techniques are still required to distinguish between uncomplicated and complicated forms of CD. Methods We set out to investigate the potential use of novel serum parameters, including IL-6, IL-8, IL-17, IL-22, sCD25, sCD27, granzyme-B, sMICA and sCTLA-4 in patients diagnosed with active CD, CD on a GFD, Refractory coeliac disease (RCD type I and II, and enteropathy associated T-cell lymphoma (EATL. Results In both active CD and RCDI-II elevated levels of the proinflammatory IL-8, IL-17 and sCD25 were observed. In addition, RCDII patients displayed higher serum levels of soluble granzyme-B and IL-6 in comparison to active CD patients. In contrast, no differences between RCDI and active CD or RCDII were observed. Furthermore, EATL patients displayed higher levels of IL-6 as compared to all other groups. Conclusions A series of novel serum parameters reveal distinctive immunological characteristics of RCDII and EATL in comparison to uncomplicated CD and RCDI.

  2. Research on multi-parameter monitoring of steel frame shaking-table test using smartphone

    Science.gov (United States)

    Han, Ruicong; Loh, Kenneth J.; Zhao, Xuefeng; Yu, Yan

    2017-04-01

    The numerical simulation promises an effective method to assess seismic damage of high-rise structure. But it's difficult to determine the input parameters and the simulation results are not completely consistent with the real condition. A more direct approach to evaluate the seismic damage is the structural health monitoring (SHM), which is one complex set of various kinds of sensors, devices and software, and always needs professionals. SHM system has achieved great development over recent years, especially on bridge structures. However it's not so popular on high-rise building due to its difficult implementation. Developing a low-cost and convenient monitoring technique will be helpful for the safety maintenance of high-rise building. Smartphones, which embedded with sensors, network transmission, data storage and processing system, are evolving towards crowdsourcing. The popularity of smartphones presents opportunities for implementation of portable SHM system on buildings. In this paper, multi-parameter monitoring of a three-story steel frame on shaking table under earthquake excitations was conducted with smartphone, and the comparison between smartphone and traditional sensors was provided. First, the monitoring applications on iOS platform, Orion-CC and D-viewer, were introduced. Then the experimental details were presented, including three-story frame model, sensors placement, viscous dampers and so on. Last, the acceleration and displacement time-history curves of smartphone and traditional sensors are provided and compared to prove the feasibility of the monitoring on frame under earthquake excitations by smartphone.

  3. An Accurate and Generic Testing Approach to Vehicle Stability Parameters Based on GPS and INS

    Directory of Open Access Journals (Sweden)

    Zhibin Miao

    2015-12-01

    Full Text Available With the development of the vehicle industry, controlling stability has become more and more important. Techniques of evaluating vehicle stability are in high demand. As a common method, usually GPS sensors and INS sensors are applied to measure vehicle stability parameters by fusing data from the two system sensors. Although prior model parameters should be recognized in a Kalman filter, it is usually used to fuse data from multi-sensors. In this paper, a robust, intelligent and precise method to the measurement of vehicle stability is proposed. First, a fuzzy interpolation method is proposed, along with a four-wheel vehicle dynamic model. Second, a two-stage Kalman filter, which fuses the data from GPS and INS, is established. Next, this approach is applied to a case study vehicle to measure yaw rate and sideslip angle. The results show the advantages of the approach. Finally, a simulation and real experiment is made to verify the advantages of this approach. The experimental results showed the merits of this method for measuring vehicle stability, and the approach can meet the design requirements of a vehicle stability controller.

  4. Prediabetes Exhibits Decreased Disposition Index Correlated with Deterioration of Glycemic Parameters in Nonobese Japanese Subjects: A Cross-Sectional Study from Medical Examination.

    Science.gov (United States)

    Takeda, Yasutaka; Fujita, Yukihiro; Yanagimachi, Tsuyoshi; Honjo, Jun; Abiko, Atsuko; Asai, Mahito; Haneda, Masakazu

    2017-08-01

    Prediabetes, defined as impaired fasting glucose (IFG) and impaired glucose tolerance (IGT), likely develops to type 2 diabetes mellitus (DM) and independently increases cardiovascular risk. We employed disposition index (DI), a new metabolic parameter indicating the pancreatic beta cell function adjusted for insulin resistance, and investigated whether it could be altered in Japanese population with prediabetes and associated with early glucose intolerance. A total of 102 adults who underwent an oral glucose tolerance test at the medical screening were designated to normal glucose tolerance (NGT), IFG, IGT, and DM. We calculated insulinogenic index (IGI) and homeostasis model assessment (HOMA) of β cell function (HOMA-β) as insulin secretory function, HOMA-insulin resistance (HOMA-IR), and quantitative insulin sensitivity check index (QUICKI) as insulin resistance and DI, and assessed correlations between these indices and glycemic parameters. We observed graded increase of glycemic parameters in the order of NGT, IFG, IGT, and DM. HOMA-IR was significantly higher only in DM compared with NGT, although HOMA-β, IGI, and QUICKI showed no significant differences among the groups. In contrast, DI was significantly lower in IFG, IGT, and DM compared with NGT. In correlation analysis, glycemic parameters related positively to HOMA-IR, but inversely to DI. Only two parameters, IGI and particularly DI, were significantly decreased in the subjects with 1-hr postload glucose >8.6 mmol/L previously proposed as a predictor of type 2 diabetes. Our results suggest that reduction of DI promptly reflects the alteration of early glucose intolerance in Japanese population presenting with prediabetes.

  5. Equity in HIV testing: evidence from a cross-sectional study in ten Southern African countries

    Directory of Open Access Journals (Sweden)

    Mitchell Steven

    2010-09-01

    Full Text Available Abstract Background HIV testing with counseling is an integral component of most national HIV and AIDS prevention strategies in southern Africa. Equity in testing implies that people at higher risk for HIV such as women; those who do not use condoms consistently; those with multiple partners; those who have suffered gender based violence; and those who are unable to implement prevention choices (the choice-disabled are tested and can have access to treatment. Methods We conducted a household survey of 24,069 people in nationally stratified random samples of communities in Botswana, Lesotho, Malawi, Mozambique, Namibia, South Africa, Swaziland, Tanzania, Zambia, and Zimbabwe. We asked about testing for HIV in the last 12 months, intention to test, and about HIV risk behaviour, socioeconomic indicators, access to information, and attitudes related to stigma. Results Across the ten countries, seven out of every ten people said they planned to have an HIV test but the actual proportion tested in the last 12 months varied from 24% in Mozambique to 64% in Botswana. Generally, people at higher risk of HIV were not more likely to have been tested in the last year than those at lower risk, although women were more likely than men to have been tested in six of the ten countries. In Swaziland, those who experienced partner violence were more likely to test, but in Botswana those who were choice-disabled for condom use were less likely to be tested. The two most consistent factors associated with HIV testing across the countries were having heard about HIV/AIDS from a clinic or health centre, and having talked to someone about HIV and AIDS. Conclusions HIV testing programmes need to encourage people at higher risk of HIV to get tested, particularly those who do not interact regularly with the health system. Service providers need to recognise that some people are not able to implement HIV preventive actions and may not feel empowered to get themselves

  6. A pendulum test as a tool to evaluate viscous friction parameters in the equine fetlock joint.

    Science.gov (United States)

    Noble, Prisca; Lumay, Geoffroy; Coninx, Marc; Collin, Bernard; Magnée, Adrien; Lecomte-Beckers, Jacqueline; Denoix, Jean M; Serteyn, Didier

    2011-05-01

    An equine fetlock joint pendulum test was studied and the influence of post mortem time and intra-articular lipid solvent on the viscous frictional response examined. Fresh equine digits (group 1, n=6 controls; group 2, n=6 lipid solvent) were mounted on a pendulum tribometer. Assuming that pendular joint damping could be modelled by a harmonic oscillator fluid damping (HOFD), damping time (τ), viscous damping coefficient (c) and friction coefficient (μ) were monitored for 5h under experimental conditions (400N; 20°C). In all experiments, pendular joint damping was found to follow an exponential decay function (R(2)=0.99714), which confirmed that joint damping was fluid. The evolution of τ, c and μ was found to be significantly (Plubricating ability was compromised. This equine pendulum test could be used to test the efficacy of various bio-lubricant treatments. Copyright © 2010 Elsevier Ltd. All rights reserved.

  7. Genetic parameters and alternatives for evaluation and ranking of Nellore young bulls in pasture performance tests

    Directory of Open Access Journals (Sweden)

    Breno de Oliveira Fragomeni

    2013-08-01

    Full Text Available The objective of this study was to estimate (covariance components for weight at 550 days, average daily gain and an index with both traits, and to compare alternatives for evaluation and ranking of Nellore young bulls in pasture performance tests. The heritability estimates were 0.73, 0.31 and 0.44 for weight at 550 days, average daily gain and index, respectively. Animals were ranked according to their predicted breeding values or the phenotypic deviations in relation to the mean of the test. Although the correlations between breeding values and phenotypic deviations were high, there were differences in the number of animals selected in common when the selection criteria were the predicted breeding values or the phenotypic deviations. Mixed models are more appropriate than the least squares method and should be utilized in the evaluation of young bulls in performance tests.

  8. Comparison of ALE and SPH Simulations of Vertical Drop Tests of a Composite Fuselage Section into Water

    Science.gov (United States)

    Jackson, Karen E.; Fuchs, Yvonne T.

    2008-01-01

    Simulation of multi-terrain impact has been identified as an important research area for improved prediction of rotorcraft crashworthiness within the NASA Subsonic Rotary Wing Aeronautics Program on Rotorcraft Crashworthiness. As part of this effort, two vertical drop tests were conducted of a 5-ft-diameter composite fuselage section into water. For the first test, the fuselage section was impacted in a baseline configuration without energy absorbers. For the second test, the fuselage section was retrofitted with a composite honeycomb energy absorber. Both tests were conducted at a nominal velocity of 25-ft/s. A detailed finite element model was developed to represent each test article and water impact was simulated using both Arbitrary Lagrangian Eulerian (ALE) and Smooth Particle Hydrodynamics (SPH) approaches in LS-DYNA, a nonlinear, explicit transient dynamic finite element code. Analytical predictions were correlated with experimental data for both test configurations. In addition, studies were performed to evaluate the influence of mesh density on test-analysis correlation.

  9. Test of a new method for seismic indices and granulation parameters extraction

    Directory of Open Access Journals (Sweden)

    Peralta R. A.

    2015-01-01

    Full Text Available In the framework of the data base project SSI (Stellar Seismic Indicesb, we have developed and tested a new method aiming at optimizing the simultaneous measurement of both the seismic indices characterizing the oscillations (Δν, νmax and the indices characterizing the granulation signature. Here, we describe this method which is intended to take advantage of the MLE (maximum likelihood estimate algorithm combined with the parametrized representation of the red giants pulsation spectrum following the Universal Pattern [6]. We report its performances tested on Monte Carlo simulations.

  10. Parameter Uniqueness And Uncertainty Associated For Multirate Transport Models Applied To Core-Scale Test Data

    Science.gov (United States)

    Kuhlman, K. L.; Malama, B.; James, S. C.

    2011-12-01

    Breakthrough data collected in a set of laboratory tracer experiments are used to constrain the multirate mass transport model STAMMT-L. The uniqueness and variance of the estimated parameters are explored using both Gauss-Marquardt-Levenberg (PEST) and Markov-Chain Monte Carlo (DREAM) algorithms. The efficacy and uniqueness of different multirate distribution types (e.g., lognormal, beta, gamma) for a given dataset are compared. The information content of the different portions of the breakthrough curve (i.e., rising limb, peak, tail) is also explored with this forward model and these inverse modeling tools. Sandia National Laboratories is a multi-program laboratory managed and operated by Sandia Corporation, a wholly owned subsidiary of Lockheed Martin Corporation, for the U.S. Department of Energy's National Nuclear Security Administration under contract DE-AC04-94AL85000.

  11. Testing variational estimation of process parameters and initial conditions of an earth system model

    Directory of Open Access Journals (Sweden)

    Simon Blessing

    2014-03-01

    Full Text Available We present a variational assimilation system around a coarse resolution Earth System Model (ESM and apply it for estimating initial conditions and parameters of the model. The system is based on derivative information that is efficiently provided by the ESM's adjoint, which has been generated through automatic differentiation of the model's source code. In our variational approach, the length of the feasible assimilation window is limited by the size of the domain in control space over which the approximation by the derivative is valid. This validity domain is reduced by non-smooth process representations. We show that in this respect the ocean component is less critical than the atmospheric component. We demonstrate how the feasible assimilation window can be extended to several weeks by modifying the implementation of specific process representations and by switching off processes such as precipitation.

  12. Parameters Optimization for a Novel Vacuum Laser Acceleration Test at BNL-ATF

    CERN Document Server

    Shao, Lei; Zhou, Feng

    2005-01-01

    This paper presents a new VLA theory model which has revealed that the injection electrons with low energy and small incident angle relative to the laser beam are captured and significantly accelerated in a strong laser field. For the further step for verifying the novel-VLA mechanics, we propose to use the BNL-ATF Terawatt CO2 laser and a high-brightness electron beam to carry out a proof-of-principle beam experiment. Experiment setup including the laser injection optics and electron extraction system and beam diagnostics is presented. Extensive optimized simulation results with ATF practical parameters are also presented, which shows that even when the laser intensity is not very high, the net energy gain still can be seen obviously. This could be prospect for a new revolution of vacuum laser acceleration.

  13. Immunochemical parameters of some commercial conjugates for the fluorescent treponemal antibody-absorption test.

    Science.gov (United States)

    Hunter, E F; Smith, J F; Lewis, J S; McGrew, B E; Schmale, J D

    1972-06-01

    Fluorescein-labeled anti-human globulins were examined to determine the need for standardization of conjugates used in the fluorescent treponemal antibody-absorption (FTA-ABS) test. Twenty-one of 33 conjugates submitted by commercial manufacturers to the Reagents Control Activity, Venereal Disease Research Laboratory, for evaluation in the FTA-ABS test were available for study. Conjugates, after evaluation in FTA-ABS performance tests, were examined by immunoelectrophoresis, by titration against immunoglobulins G and M (IgG, IgM) with FTA-ABS techniques, and by the biuret protein and fluorescein diacetate methods for determining fluorescein to protein (F/P) ratios. The conjugates were predominately anti-IgG globulin with anti-light-chain activity. Differences were noted in the ability of some conjugates to detect IgM antibody. The F/P ratios of those conjugates that could be determined varied from 2.6 to 17.8 mug of fluorescein per mg of protein. The need to identify and standardize both the immunologic capabilities and the optimum F/P ratio for FTA-ABS test conjugates is presented.

  14. Novel field test design for acquisition of DC and AC parameters during service

    DEFF Research Database (Denmark)

    Thorsteinsson, Sune; Poulsen, Peter Behrensdorff; Schou, Jørgen

    2016-01-01

    potential for more. In this work we describe a field test design where the modules are operating at their maximum power point, and via relays is switched out one by one for acquisition of an IV curve and an impedance spectrum. Some of the modules involved will undergo stimuli to accelerate certain...

  15. Time-of-Day Effects on EMG Parameters During the Wingate Test in Boys

    National Research Council Canada - National Science Library

    Souissi, Hichem; Chtourou, Hamdi; Chaouachi, Anis; Chamari, Karim; Souissi, Nizar; Amri, Mohamed

    2012-01-01

    ... (measurement of muscle power and fatigue) at 07:00 and 17:00-h on separate days. Surface EMG activity was recorded in the Vastus lateralis, rectus femoris and vastus medialis muscles throughout the test and analyzed over a 5-s span...

  16. Tire measurements, forces and moments. Workpackage 2: analysis of parameters influencing tyre test results

    NARCIS (Netherlands)

    Oosten, J.J.M. van; Augustin, M.; Gnadler, R.; Unrau, H.J.

    1998-01-01

    In February 1996 the EC started the TIME Project (TIre MEasurements). The projects aim is the development of a common test procedure that will be reliable and consistent with realistic driving conditions. The facts which lead to this activity are, on the one hand, the deviations between the force

  17. Underground Test Area Subproject Phase I Data Analysis Task. Volume V - Transport Parameter and Source Term Data Documentation Package

    Energy Technology Data Exchange (ETDEWEB)

    None

    1996-12-01

    Volume V of the documentation for the Phase I Data Analysis Task performed in support of the current Regional Flow Model, Transport Model, and Risk Assessment for the Nevada Test Site Underground Test Area Subproject contains the transport parameter and source term data. Because of the size and complexity of the model area, a considerable quantity of data was collected and analyzed in support of the modeling efforts. The data analysis task was consequently broken into eight subtasks, and descriptions of each subtask's activities are contained in one of the eight volumes that comprise the Phase I Data Analysis Documentation.

  18. Positron collisions with molecular hydrogen: cross sections and annihilation parameters calculated using the R-matrix with pseudo-states method

    Energy Technology Data Exchange (ETDEWEB)

    Zhang Rui; Franz, Jan; Tennyson, Jonathan [Department of Physics and Astronomy, University College London, Gower Street, London WC1E 6BT (United Kingdom); Baluja, K L, E-mail: j.tennyson@ucl.ac.uk [Department of Physics and Astrophysics University of Delhi, Delhi 110 007 (India)

    2011-01-14

    The molecular R-matrix with pseudo-states (MRMPS) method is employed to study positron collisions with H{sub 2}. The calculations employ pseudo-continuum orbital sets containing up to h (l = 5) functions. Use of these high l functions is found to give converged eigenphase sums. Below the positronium formation threshold, the calculated cross sections agree with other high-accuracy theories and generally with the measurements. Calculation of the positron annihilation parameter Z{sub eff} with the MRMPS wavefunctions gives values significantly higher than other R-matrix wavefunctions but still do not completely converge with h functions. Extrapolation to higher l-values leads to a predicted value of Z{sub eff} for H{sub 2} of about 10.4. The MRMPS method is both completely general and ab initio; it can therefore be applied to positron collisions with other molecular targets.

  19. Influence of different test parameters on the microshear bond strength of two simplified etch-and-rinse adhesives.

    Science.gov (United States)

    Andrade, Andrea M; Garcia, Eugenio Jose; El-Askary, Farid S; Reis, Alessandra; Loguercio, Alessandro D; Grande, Rosa Helena

    2014-08-01

    To evaluate the effect of different test parameters on the resin-dentin microshear bond strength (μSBS). A 1.5-mm-thick dentin disk was prepared in each of 140 human molars. The disks were divided into five groups to test the following variables: time of adhesive light polymerization (n = 20), storage time (n = 40), bonding area (n = 40), Tygon tube removal (n = 20), and time of composite placement (n = 20). The adhesives were applied and each specimen was subjected to μSBS testing. All fractured specimens were observed with SEM. The data from each experiment were subjected to two-way ANOVA and Tukey's test (α = 0.05). The storage time, bonding area, and Tygon tube removal did not influence the μSBS. Higher μSBS values were found when empty Tygon tubes were filled after positioning and when the adhesive was light polymerized before Tygon tube placement (p < 0.05). Differences in test parameters affected the μSBS of adhesives, especially the time of adhesive light polymerization and composite placement.

  20. Longevity-associated mitochondrial DNA 5178 C/A polymorphism modulates the effects of coffee consumption on erythrocytic parameters in Japanese men: an exploratory cross-sectional analysis.

    Science.gov (United States)

    Kokaze, Akatsuki; Ishikawa, Mamoru; Matsunaga, Naomi; Karita, Kanae; Yoshida, Masao; Ohtsu, Tadahiro; Ochiai, Hirotaka; Shirasawa, Takako; Nanri, Hinako; Saga, Nobuyuki; Ohtsu, Iichiro; Hoshino, Hiromi; Takashima, Yutaka

    2014-12-20

    Mitochondrial DNA 5178 cytosine/adenine (Mt5178 C/A) polymorphism reportedly modulates the effects of coffee consumption on the risk of hypertension, dyslipidemia and abnormal glucose tolerance. The objective of this analysis was to investigate whether Mt5178 C/A polymorphism modifies the effects of coffee consumption on erythrocytic parameters in male Japanese health check-up examinees. A total of 436 men (mean age ± standard deviation, 54.1 ± 7.8 years) were selected from among individuals visiting the hospital for regular medical check-ups. After Mt5178 C/A genotyping, an exploratory cross-sectional analysis assessing the joint effects of Mt5178 C/A polymorphism and coffee consumption on red blood cell counts, hematocrit and hemoglobin was conducted. For Mt5178C genotypic men, after adjustment for age, body mass index, alcohol consumption, habitual smoking and green tea consumption, coffee consumption significantly decreased red blood cell counts (P for trend = 0.022) and hemoglobin (P for trend = 0.035). The risk of anemia, defined as hemoglobin of coffee consumption (P for trend = 0.078), and the adjusted odds ratio for anemia was significantly higher in men who consumed ≥4 cups of coffee per day than in those who consumed coffee consumption possibly reduced the risk of anemia (P for trend = 0.049). However, after the aforementioned adjustment, the statistical significance disappeared (P for trend = 0.137). This exploratory cross-sectional analysis suggests that Mt5178 C/A polymorphism modulates the effects of coffee consumption on erythrocytic parameters and the risk of anemia in male Japanese health check-up examinees.

  1. An effective automatic procedure for testing parameter identifiability of HIV/AIDS models.

    Science.gov (United States)

    Saccomani, Maria Pia

    2011-08-01

    Realistic HIV models tend to be rather complex and many recent models proposed in the literature could not yet be analyzed by traditional identifiability testing techniques. In this paper, we check a priori global identifiability of some of these nonlinear HIV models taken from the recent literature, by using a differential algebra algorithm based on previous work of the author. The algorithm is implemented in a software tool, called DAISY (Differential Algebra for Identifiability of SYstems), which has been recently released (DAISY is freely available on the web site http://www.dei.unipd.it/~pia/ ). The software can be used to automatically check global identifiability of (linear and) nonlinear models described by polynomial or rational differential equations, thus providing a general and reliable tool to test global identifiability of several HIV models proposed in the literature. It can be used by researchers with a minimum of mathematical background.

  2. A pendulum test as a tool to evaluate viscous friction parameters in the equine fetlock joint

    OpenAIRE

    Noble, Prisca; Lumay, Geoffroy; Coninx, Marc; Collin, Bernard; Magnée, Adrien; LECOMTE-BECKERS, Jacqueline; Denoix; Serteyn, Didier

    2011-01-01

    An equine fetlock joint pendulum test was studied and the influence of post mortem time and intra-articular lipid solvent on the viscous frictional response examined. Fresh equine digits (group 1, n=6 controls; group 2, n=6 lipid solvent) were mounted on a pendulum tribometer. Assuming that pendular joint damping could be modelled by a harmonic oscillator fluid damping (HOFD), damping time (τ), viscous damping coefficient (c) and friction coefficient (μ) were monitored for 5h under experiment...

  3. Association between mild cognitive impairment and trajectory-based spatial parameters during timed up and go test using a laser range sensor.

    Science.gov (United States)

    Nishiguchi, Shu; Yorozu, Ayanori; Adachi, Daiki; Takahashi, Masaki; Aoyama, Tomoki

    2017-08-08

    The Timed Up and Go (TUG) test may be a useful tool to detect not only mobility impairment but also possible cognitive impairment. In this cross-sectional study, we used the TUG test to investigate the associations between trajectory-based spatial parameters measured by laser range sensor (LRS) and cognitive impairment in community-dwelling older adults. The participants were 63 community-dwelling older adults (mean age, 73.0 ± 6.3 years). The trajectory-based spatial parameters during the TUG test were measured using an LRS. In each forward and backward phase, we calculated the minimum distance from the marker, the maximum distance from the x-axis (center line), the length of the trajectories, and the area of region surrounded by the trajectory of the center of gravity and the x-axis (center line). We measured mild cognitive impairment using the Mini-Mental State Examination score (26/27 was the cut-off score for defining mild cognitive impairment). Compared with participants with normal cognitive function, those with mild cognitive impairment exhibited the following trajectory-based spatial parameters: short minimum distance from the marker (p = 0.044), narrow area of center of gravity in the forward phase (p = 0.012), and a large forward/whole phase ratio of the area of the center of gravity (p = 0.026) during the TUG test. In multivariate logistic regression analyses, a short minimum distance from the marker (odds ratio [OR]: 0.82, 95% confidence interval [CI]: 0.69-0.98), narrow area of the center of gravity in the forward phase (OR: 0.01, 95% CI: 0.00-0.36), and large forward/whole phase ratio of the area of the center of gravity (OR: 0.94, 95% CI: 0.88-0.99) were independently associated with mild cognitive impairment. In conclusion, our results indicate that some of the trajectory-based spatial parameters measured by LRS during the TUG test were independently associated with cognitive impairment in older adults. In particular, older adults with

  4. The relationship between Test Takers’ Multiple Intelligences and Their Performance on the Reading Sections of TOEFL and IELTS

    Directory of Open Access Journals (Sweden)

    Minoo Alemi

    2010-04-01

    Full Text Available The present study aimed at investigating the hypothetical relationship between the multiple intelligences of test takers and their performance on the reading sections of TOEFL and IELTS. Howard Gardner’s theory of multiple intelligences suggests that intelligence is not a single and solely inborn capacity, rather a multiple construct which is only partly genetic, and can be crystallized or paralyzed over one’s lifetime. Based on the theory, there are eight types of intelligence: linguistic, mathematical, musical, bodily, spatial, intrapersonal, interpersonal and naturalist, but the list is not exhaustive. The multiple intelligences of test takers were estimated by means of MIDAS, the Multiple Intelligences Developmental Assessment Scales, developed by Shearer (1994. Subsequently, the bias detection for the reading section of TOEFL was carried out on 90 participants, and this subtest was found to correlate positively with linguistic and logical intelligences. By the same token, 89 out of the 163 participants in the study were included in the analysis of the relationship between the multiple intelligences of test takers and their performance on the reading section of IELTS, and this test proved biased toward linguistic and spatial intelligences. The implications concern the inadequacy of the definition of language proficiency .Moreover, Measurement-Driven Instruction courses and preparatory materials of the two proficiency tests, TOEFL and IELTS, can benefit from the results of the study by being designed in such a way as to represent the intelligences which are positively correlated with performance on the tests in question.

  5. Electronic music effects on neuromuscular and cardiovascular systems and psychophysiological parameters during exhaustive incremental test

    Directory of Open Access Journals (Sweden)

    B.P.C. Smirmaul

    2011-01-01

    Full Text Available The aim of this study was to analyze the music effects on physiological and psychophysiological responses, as well as on the maximum power output attained during an incremental test. A sample of 10 healthy individuals (20.8 ± 1.4 years, 77.0 ± 12.0 kg, 179.2 ± 6.3 cm participated in this study. It was recorded the electromyographic activity (muscles Rectus Femoris − RF and Vastus Lateralis − VL, heart rate (HR, rating of perceived exertion (RPE, ratings of perceived time (RPT and the maximum power output attained (PMax during music (WM and without music (WTM conditions. The individuals completed four maximal incremental tests (MIT ramp-like on a cycle simulator with initial load of 100 W and increments of 10 W•min-1. The mean values of PMax between conditions WTM (260.5 ± 27.7 W and WM (263.2 ± 17.2 W were not statistically different. The comparison between the rates of increase of the values expressed in root-mean-square (RMS and median frequency (MF for both muscles (RF and VL also showed no statistical difference, as well as HR, RPE and RPT. It is concluded that the use of the electronic music during an incremental test to exhaustion showed no effect on the analyzed variables for the investigated group.

  6. The impact of inherited thrombophilia on first trimester combined aneuploidy screening test parameters.

    Science.gov (United States)

    Karsli, Mehmet Fatih; Baser, Eralp; Seckin, Kerem Doga; Yeral, Mahmut İlkin; Togrul, Cihan; Ugur, Mustafa

    2014-03-01

    To determine whether inherited thrombophilia affects components of first trimester combined aneuploidy screening test. A case-control study was performed between January 1st and December 31st 2011, at a tertiary referral hospital. Singleton pregnancies with inherited thrombophilia that underwent first trimester (11-13(+6) week) combined aneuploidy screening test were included in the study. Pregnancy associated plasma protein-A (PAPP-A), free beta-human chorionic gonadotropin (fbHCG) and fetal nuchal translucency (NT) were compared between the study group and controls. Within the study period, 15,881 women with singleton pregnancies had a combined first trimester aneuploidy screening test at our institution. Among these, 207 women met the inclusion criteria. A control group that comprised 625 women with similar gestational age was generated, using a 1:3 ratio. PAPP-A levels were significantly higher, whereas fbHCG levels and fetal NT measurements were lower in women with inherited thrombophilia (p < 0.001). Our study suggested that PAPP-A, free b-HCG and NT MoM levels display alterations in women with inherited thrombophilia. Future trials are needed to assess the need for readjustment of risk in these patients.

  7. Electronic music effects on neuromuscular and cardiovascular systems and psychophysiological parameters during exhaustive incremental test

    Directory of Open Access Journals (Sweden)

    Bruno de Paula Caraça Smirmaul

    2011-09-01

    Full Text Available The aim of this study was to analyze the music effects on physiological and psychophysiological responses, as well as on the maximum power output attained during an incremental test. A sample of 10 healthy individuals (20.8 ± 1.4 years, 77.0 ± 12.0 kg, 179.2 ± 6.3 cm participated in this study. It was recorded the electromyographic activity (muscles Rectus Femoris − RF and Vastus Lateralis − VL, heart rate (HR, rating of perceived exertion (RPE, ratings of perceived time (RPT and the maximum power output attained (PMax during music (WM and without music (WTM conditions. The individuals completed four maximal incremental tests (MIT ramp-like on a cycle simulator with initial load of 100 W and increments of 10 W·min-1. The mean values of PMax between conditions WTM (260.5 ± 27.7 W and WM (263.2 ± 17.2 W were not statistically different. The comparison between the rates of increase of the values expressed in root-mean-square (RMS and median frequency (MF for both muscles (RF and VL also showed no statistical difference, as well as HR, RPE and RPT. It is concluded that the use of the electronic music during an incremental test to exhaustion showed no effect on the analyzed variables for the investigated group.

  8. Neuroendocrine stimulatory tests of hypothalamus-pituitary-adrenal axis in psoriasis and correlative implications with psychopathological and immune parameters.

    Science.gov (United States)

    Karanikas, Evangelos; Harsoulis, Faidon; Giouzepas, Ioannis; Griveas, Ioannis; Chrisomallis, Fotios

    2009-01-01

    Psoriasis constitutes one of the most representative examples of psychosomatic disorders. The published work investigating the psychological parameters and the way they interact during the course of the disease is extensive, whereas only a few studies have focused on the neuroendocrine framework of psoriasis. In the present study, the objective was to investigate the neuroendocrine parameters of psoriasis and the way they interact with psychopathological and immune variables. Patients with psoriasis (n=24) and the same number of matched healthy controls underwent psychiatric evaluation with interviews and psychometric questionnaires. Both of the groups underwent the corticotropin-releasing hormone (CRH) test and the dexamethasone suppression test (DST) to investigate functional parameters of the hypothalamus-pituitary-adrenal (HPA) axis. The evaluation of immune variables included the estimation of the distribution of T-cell and natural killer lymphocytes. Levels of depressive and anxiety features were increased within subjects with psoriasis and they were significantly correlated with stressful life events and the extent of the disease. The adrenocorticotrophic hormone and cortisol levels increased after CRH infusion without significant differences between the two groups and the psoriatic subjects' cortisol suppression after DST was within normal range, though relatively blunted. No significant correlations were identified among neuroendocrine, psychopathological and immune parameters. No particular neuroendocrine profile has been identified among psoriatic patients and the hypothesized interaction with psychopathological and immune parameters was not replicated. Nevertheless, it is still premature to exclude the possibility that a subtle latent alteration of the HPA axis function might exist, in psoriasis, either stemming from the psychopathology or from the disease per se.

  9. Acoustic Quality of the 40- by 80- Foot Wind Tunnel Test Section After Installation of a Deep Acoustic Lining

    Science.gov (United States)

    Soderman, Paul T.; Jaeger, Stephen M.; Hayes, Julie A.; Allen, Christopher S.

    2002-01-01

    A recessed, 42-inch deep acoustic lining has been designed and installed in the 40- by 80- Foot Wind Tunnel (40x80) test section to greatly improve the acoustic quality of the facility. This report describes the test section acoustic performance as determined by a detailed static calibration-all data were acquired without wind. Global measurements of sound decay from steady noise sources showed that the facility is suitable for acoustic studies of jet noise or similar randomly generated sound. The wall sound absorption, size of the facility, and averaging effects of wide band random noise all tend to minimize interference effects from wall reflections. The decay of white noise with distance was close to free field above 250 Hz. However, tonal sound data from propellers and fans, for example, will have an error band to be described that is caused by the sensitivity of tones to even weak interference. That error band could be minimized by use of directional instruments such as phased microphone arrays. Above 10 kHz, air absorption began to dominate the sound field in the large test section, reflections became weaker, and the test section tended toward an anechoic environment as frequency increased.

  10. A Cross-Sectional Evaluation of Student Achievement Using Standardized and Performance-Based Tests

    Science.gov (United States)

    Pinter, Brad; Matchock, Robert L.; Charles, Eric P.; Balch, William R.

    2014-01-01

    Three groups of undergraduates (42 senior graduating psychology majors, 27 first-year premajors taking introductory psychology, and 24 first-year, high-performing nonmajors taking introductory psychology) completed the Psychology Major Field Test (MFT) and a short-answer (SA) essay test on reasoning about core knowledge in psychology. Graduating…

  11. Correlation of magnesium intake with metabolic parameters, depression and physical activity in elderly type 2 diabetes patients: a cross-sectional study.

    Science.gov (United States)

    Huang, Jui-Hua; Lu, Yi-Fa; Cheng, Fu-Chou; Lee, John Ning-Yuean; Tsai, Leih-Ching

    2012-06-13

    Type 2 diabetes mellitus is a major global public health problem in the worldwide and is increasing in aging populations. Magnesium intake may be one of the most important factors for diabetes prevention and management. Low magnesium intake may exacerbate metabolic abnormalities. In this study, the relationships of magnesium intake with metabolic parameters, depression and physical activity in elderly patients with type 2 diabetes were investigated. This cross-sectional study involved 210 type 2 diabetes patients aged 65 years and above. Participants were interviewed to obtain information on lifestyle and 24-hour dietary recall. Assessment of depression was based on DSM-IV criteria. Clinical variables measured included anthropometric measurements, blood pressure, and biochemical determinations of blood and urine samples. Linear regression was applied to determine the relationships of magnesium intake with nutritional variables and metabolic parameters. Among all patients, 88.6% had magnesium intake which was less than the dietary reference intake, and 37.1% had hypomagnesaemia. Metabolic syndromes and depression were associated with lower magnesium intake (p magnesium intake and HDL-cholesterol (p = 0.005). Magnesium intake was inversely correlated with triglyceride, waist circumference, body fat percent and body mass index (p magnesium intake (p for trend = 0005). Waist circumference, body fat percentage, and body mass index were significantly lower with increase quartile of magnesium intake (p for trend magnesium intake (p for trend magnesium intake was related to high physical activity level and demonstrated lower serum magnesium levels. Serum magnesium was not significantly associated with metabolic parameters. The majority of elderly type 2 diabetes who have low magnesium intake may compound this deficiency with metabolic abnormalities and depression. Future studies should determine the effects of increased magnesium intake or magnesium

  12. Design of an experimental setup to measure the K-shell photoelectric cross sections and other atomic parameters at K edge

    Energy Technology Data Exchange (ETDEWEB)

    Garcia-Alvarez, J.A.; Lopez-Pino, N.; Rizo, O. Diaz; Corrales, Y.; Padilla-Cabal, F.; Perez-Liva, M.; Alessandro, K.D.; Maidana, N.L. [Instituto Superior de Tecnologia y Ciencias Aplicadas (InSTEC), La Habana (Cuba)

    2010-07-01

    Full text: An experimental setup to measure the K shell jump ratio, jump factor and the ratio of total to K-shell photo-electric cross section at K edge was designed with Monte Carlo (MC) simulations, using the MCNPX V 2.6 code. In our arrangement, Bremsstrahlung photons, produced by beta particles from a {sup 90}Sr- {sup 90}Y source (activity - 0.1 mCi) hitting a thin Nickel converter, were used to irradiate the targets. The incident and transmitted spectra were measured with an HPGe detector coupled to conventional electronics. A sharp decrease in intensity at the K-shell binding energy was observed in the transmitted spectra, which, after corrections for photon attenuation, showed the known behavior for the photoelectric cross section as function of photon energy. The photon beam divergence effects were corrected with a calibration curve calculated with MC from simulations of a parallel and a divergent beam. Targets of Dy, Ta, Pt and Au were used to test the setup. The obtained data were processed by fitting either the total cross section to a sigmoidal function or the cross section branches around the K edge to the empirical law {sigma} = (A/E){sup n}. The results obtained using the first method show the influence of detector energy resolution in the data, because the measured jump at the K edge is not so sharp as it should be. Furthermore, additional calculations were done to obtain the anomalous scattering factors and the K-shell oscillator strengths. The values obtained for the K-shell photoelectric cross sections were compared with theoretical and other experimental data. In most cases, relative deviations below 10% were found. (author)

  13. Hydro-mechanical constitutive model for unsaturated compacted bentonite-sand mixture (BSM): Laboratory tests, parameter calibrations, modifications, and applications

    Science.gov (United States)

    Priyanto, D. G.; Man, A. G.; Blatz, J. A.; Dixon, D. A.

    A bentonite-sand mixture (BSM) is one of the clay-based sealing components proposed for use in a Canadian deep geological repository (DGR) for used nuclear fuel. Numerical modelling to assess the overall design of the proposed DGR requires characterisation of the hydraulic-mechanical (H-M) of each of the components of the sealing system, including the BSM. The BSM currently under consideration is a 50/50 mixture (by dry mass) of bentonite and well-graded silica sand, compacted to a dry density of at least 1.67 Mg/m 3. This paper presents the H-M constitutive model parameters, calibrated for BSM specimens under saturated and unsaturated conditions, based on various laboratory tests. A set of parameters for an elastoplastic model for unsaturated soil, Basic Barcelona Model (BBM), have been determined to simulate the mechanical behaviour of the BSM specimen. A set of parameters for van Genuchten’s Soil-Water Characteristic Curve (SWCC) and Kozeny’s hydraulic permeability model have been determined to simulate the hydraulic behaviour of the BSM specimen. Using a finite element computer code, CODE_BRIGHT, these sets of parameters have been used to simulate H-M processes in BSM specimens during water infiltration under constant volume (CV) and constant mean stress (CMS) boundary conditions. The key features of the selected constitutive models that are different from the laboratory tests of the BSM specimen have been summarised. The functions to improve the capability of the selected constitutive models to match the laboratory test results of the BSM specimen have been proposed.

  14. An Investigation of Reaming Test Parameters Used for Cutting Fluid Evaluations

    DEFF Research Database (Denmark)

    De Chiffre, Leonardo; Zeng, Z.; Belluco, Walter

    2001-01-01

    It has been suggested that the lubricating efficiency of cutting fluids can be assessed using a reaming test that measures cutting forces and surface roughness. In the present work, an investigation was undertaken to ream austenitic stainless steel using water based fluids and to evaluate...... of the force analysis, are discussed. For mean reaming torque, a measurement uncertainty of 5 percent (with 6 repetitions) was achieved. Results show that torque and thrust measurements offer a reliable description of the lubricating properties of cutting fluids, while conventional surface roughness evaluation...

  15. Test anxiety and self-esteem in senior high school students: a cross-sectional study.

    Science.gov (United States)

    Sarı, Seda Aybüke; Bilek, Günal; Çelik, Ekrem

    2018-02-01

    In this study, it is aimed to determine the level of test anxiety and self-esteem in the high school students preparing for the university exam in Bitlis, Turkey, and to investigate the effect of test anxiety on self-esteem. Seven-hundred and twenty-four high school students who were preparing for the university entrance examination in Bitlis participated in the study. A questionnaire which includes socio-demographic data form, Rosenberg Self-Esteem Scale and Revised Test Anxiety Scale was prepared as an e-questionnaire for the students to fill easily and uploaded to the Bitlis State Hospital's website. Schools were called and informed for the students to fill out the e-questionnaire on the Internet. The most important findings from our study are that gender is influential on test anxiety and self-esteem score and test anxiety level are negatively correlated. It was observed that female students had more test anxiety than male students and those who had higher self-esteem had less test anxiety. Consequently, our study shows that university entrance examination creates anxiety on students and reduces self-esteem, especially in female students.

  16. Lagrangian model of zooplankton dispersion: numerical schemes comparisons and parameter sensitivity tests

    Science.gov (United States)

    Qiu, Zhongfeng; Doglioli, Andrea M.; He, Yijun; Carlotti, Francois

    2011-03-01

    This paper presents two comparisons or tests for a Lagrangian model of zooplankton dispersion: numerical schemes and time steps. Firstly, we compared three numerical schemes using idealized circulations. Results show that the precisions of the advanced Adams-Bashfold-Moulton (ABM) method and the Runge-Kutta (RK) method were in the same order and both were much higher than that of the Euler method. Furthermore, the advanced ABM method is more efficient than the RK method in computational memory requirements and time consumption. We therefore chose the advanced ABM method as the Lagrangian particle-tracking algorithm. Secondly, we performed a sensitivity test for time steps, using outputs of the hydrodynamic model, Symphonie. Results show that the time step choices depend on the fluid response time that is related to the spatial resolution of velocity fields. The method introduced by Oliveira et al. in 2002 is suitable for choosing time steps of Lagrangian particle-tracking models, at least when only considering advection.

  17. Basic test framework for the evaluation of text line segmentation and text parameter extraction.

    Science.gov (United States)

    Brodić, Darko; Milivojević, Dragan R; Milivojević, Zoran

    2010-01-01

    Text line segmentation is an essential stage in off-line optical character recognition (OCR) systems. It is a key because inaccurately segmented text lines will lead to OCR failure. Text line segmentation of handwritten documents is a complex and diverse problem, complicated by the nature of handwriting. Hence, text line segmentation is a leading challenge in handwritten document image processing. Due to inconsistencies in measurement and evaluation of text segmentation algorithm quality, some basic set of measurement methods is required. Currently, there is no commonly accepted one and all algorithm evaluation is custom oriented. In this paper, a basic test framework for the evaluation of text feature extraction algorithms is proposed. This test framework consists of a few experiments primarily linked to text line segmentation, skew rate and reference text line evaluation. Although they are mutually independent, the results obtained are strongly cross linked. In the end, its suitability for different types of letters and languages as well as its adaptability are its main advantages. Thus, the paper presents an efficient evaluation method for text analysis algorithms.

  18. Basic Test Framework for the Evaluation of Text Line Segmentation and Text Parameter Extraction

    Directory of Open Access Journals (Sweden)

    Darko Brodić

    2010-05-01

    Full Text Available Text line segmentation is an essential stage in off-line optical character recognition (OCR systems. It is a key because inaccurately segmented text lines will lead to OCR failure. Text line segmentation of handwritten documents is a complex and diverse problem, complicated by the nature of handwriting. Hence, text line segmentation is a leading challenge in handwritten document image processing. Due to inconsistencies in measurement and evaluation of text segmentation algorithm quality, some basic set of measurement methods is required. Currently, there is no commonly accepted one and all algorithm evaluation is custom oriented. In this paper, a basic test framework for the evaluation of text feature extraction algorithms is proposed. This test framework consists of a few experiments primarily linked to text line segmentation, skew rate and reference text line evaluation. Although they are mutually independent, the results obtained are strongly cross linked. In the end, its suitability for different types of letters and languages as well as its adaptability are its main advantages. Thus, the paper presents an efficient evaluation method for text analysis algorithms.

  19. Mechanical Parameters and Post-Cracking Behaviour of HPFRC according to Three-Point and Four-Point Bending Test

    Directory of Open Access Journals (Sweden)

    Francesco Bencardino

    2013-01-01

    Full Text Available High performance fibre reinforced concrete (HPFRC is a modern structural material with a high potential and with an increasing number of structural applications. Structural design of HPFRC elements is based on the post-cracking residual strength provided by fibre reinforcement, and for structural use, a minimum mechanical performance of HPFRC must be guaranteed. To optimize the performance of HPFRC in structural members, it is necessary to establish the mechanical properties and the post-cracking and fracture behaviour in a univocal and reliable way. The best test methodology to evaluate the post-cracking and toughness properties of HPFRC is the beam bending test. Two different types of configurations are proposed: the three-point and the four-point bending tests. The overall focus of this paper is to evaluate the mechanical properties and the post-cracking and fracture behaviour of HPFRC, using the two different standard test procedures. To achieve these aims, plain and fibre concrete specimens were tested. All the test specimens were extensively instrumented to establish the strength properties, crack tip and crack mouth opening displacement, and post-cracking behaviour. The results of the two types of bending tests were critically analysed and compared to identify and highlight the differing effects of the bending load configurations on the mechanical parameters of HPFRC material.

  20. Tethered 3-min all-out test did not predict the traditional critical force parameters in inexperienced swimmers.

    Science.gov (United States)

    Kalva-Filho, Carlos A; Zagatto, Alessandro M; da Silva, Adelino S; Castanho de Araújo, Monique Y; de Almeida, Pablo B; Papoti, Marcelo

    2017-09-01

    Critical power model can be performed in tethered swimming (i.e. critical force model). Although critical force can be used to prescribe aerobic training, its determination depends on at least three exhaustive efforts in altered days. In this context, previously studies have demonstrate that critical power model can be estimated by a single 3-min all-out test (3MT), which was not investigated in swimming yet. Thus, the aim of this study was to compare the parameters obtained during the tethered swimming 3MT to those obtained during the traditional critical force model. Seven swimmers (four female and three male) underwent a tethered swimming 3MT and three exhaustive efforts to determine the traditional critical force parameters (i.e. critical force [CF] and anaerobic impulse capacity [AIC]). The critical force (CF3-MIN) and force-time integral above the CF3-MIN (AIC3-MIN) determined during the tethered 3MT were not different to CF and AIC, respectively (P value >0.55). However, these parameters were not correlated (P value >0.45). In addition, we verified large limits of agreement between CF3MIN and CF (±19.7 N), which was also observed between AIC3MIN and AIC (±0.84 Log[N·min]). These findings demonstrated that tethered 3MTs should not be used to predict traditional critical force parameters, at least when the swimmers are inexperienced in long tethered all-out efforts.

  1. Factors affecting voluntary HIV counselling and testing among men in Ethiopia: a cross-sectional survey

    OpenAIRE

    Leta Tesfaye H; Sandøy Ingvild F; Fylkesnes Knut

    2012-01-01

    Abstract Background Voluntary HIV counselling and testing (VCT) is one of the key strategies in the HIV/AIDS prevention and control programmes in Ethiopia. However, utilization of this service among adults is very low. The aim of the present study was to investigate factors associated with VCT utilization among adult men since men are less likely than women to be offered and accept routine HIV testing. Methods The study utilized data from the Ethiopian Demographic Health Survey (EDHS) 2005, w...

  2. Effects of Cracking Test Conditions on Estimation Uncertainty for Weibull Parameters Considering Time-Dependent Censoring Interval

    Directory of Open Access Journals (Sweden)

    Jae Phil Park

    2016-12-01

    Full Text Available It is extremely difficult to predict the initiation time of cracking due to a large time spread in most cracking experiments. Thus, probabilistic models, such as the Weibull distribution, are usually employed to model the initiation time of cracking. Therefore, the parameters of the Weibull distribution are estimated from data collected from a cracking test. However, although the development of a reliable cracking model under ideal experimental conditions (e.g., a large number of specimens and narrow censoring intervals could be achieved in principle, it is not straightforward to quantitatively assess the effects of the ideal experimental conditions on model estimation uncertainty. The present study investigated the effects of key experimental conditions, including the time-dependent effect of the censoring interval length, on the estimation uncertainties of the Weibull parameters through Monte Carlo simulations. The simulation results provided quantified estimation uncertainties of Weibull parameters in various cracking test conditions. Hence, it is expected that the results of this study can offer some insight for experimenters developing a probabilistic crack initiation model by performing experiments.

  3. Effects of Cracking Test Conditions on Estimation Uncertainty for Weibull Parameters Considering Time-Dependent Censoring Interval.

    Science.gov (United States)

    Park, Jae Phil; Park, Chanseok; Cho, Jongweon; Bahn, Chi Bum

    2016-12-23

    It is extremely difficult to predict the initiation time of cracking due to a large time spread in most cracking experiments. Thus, probabilistic models, such as the Weibull distribution, are usually employed to model the initiation time of cracking. Therefore, the parameters of the Weibull distribution are estimated from data collected from a cracking test. However, although the development of a reliable cracking model under ideal experimental conditions (e.g., a large number of specimens and narrow censoring intervals) could be achieved in principle, it is not straightforward to quantitatively assess the effects of the ideal experimental conditions on model estimation uncertainty. The present study investigated the effects of key experimental conditions, including the time-dependent effect of the censoring interval length, on the estimation uncertainties of the Weibull parameters through Monte Carlo simulations. The simulation results provided quantified estimation uncertainties of Weibull parameters in various cracking test conditions. Hence, it is expected that the results of this study can offer some insight for experimenters developing a probabilistic crack initiation model by performing experiments.

  4. Effects of psychological stress test on the cardiac response of public safety workers: alternative parameters to autonomic balance

    Science.gov (United States)

    Huerta-Franco, M. R.; Vargas-Luna, F. M.; Delgadillo-Holtfort, I.

    2015-01-01

    It is well known that public safety workers (PSW) face many stressful situations that yield them as high-risk population for suffering chronic stress diseases. In this multidisciplinary research the cardiac response to induced psychological stress by a short duration Stroop test was evaluated in 20 female and 19 male PSW, in order to compare traditionally used cardiac response parameters with alternative ones. Electrocardiograms have been recorded using the Eindhoven electrodes configuration for 1 min before, 3 min during and 1 min after the test. Signals analysis has been performed for the heart rate and the power spectra of its variability and of the variability of the amplitude of the R-wave, i.e. the highest peak of the electrocardiographic signal periodic sequence. The results demonstrated that the traditional autonomic balance index shows no significant differences between stages. In contrast, the median of the area of the power spectrum of the R-wave amplitude variability in the frequency region dominated by the autonomous nervous system (0.04-to-0.4 Hz) is the more sensitive parameter. Moreover, this parameter allows to identify gender differences consistent with those encountered in other studies.

  5. Comparison of Peak Oxygen Uptake and Test-Retest Reliability of Physiological Parameters between Closed-End and Incremental Upper-Body Poling Tests

    Directory of Open Access Journals (Sweden)

    Julia K. Baumgart

    2017-10-01

    Full Text Available Objective: To compare peak oxygen uptake (VO2peak and the test-retest reliability of physiological parameters between a 1-min and a 3-min closed-end and an incremental open-end upper-body poling test.Methods: On two separate test days, 24 healthy, upper-body trained men (age: 28.3 ± 9.3 years, body mass: 77.4 ± 8.9 kg, height: 182 ± 7 cm performed a 1-min, a 3-min and an incremental test to volitional exhaustion in the same random order. Respiratory parameters, heart rate (HR, blood lactate concentration (BLa, rating of perceived exertion (RPE, and power output were measured. VO2peak was determined as the single highest 30-s average. Relative reliability was assessed with the intra-class correlation coefficient (ICC2, 1 and absolute reliability with the standard error of measurement (SEM and smallest detectable change (SDC.Results: The incremental (3.50 ± 0.46 L·min−1 and 45.4 ± 5.5 mL·kg−1·min−1 and the 3-min test (3.42 ± 0.47 L·min−1 and 44.5 ± 5.5 mL·kg−1·min−1 resulted in significantly higher absolute and body-mass normalized VO2peak compared to the 1-min test (3.13 ± 0.40 L·min−1 and 40.4 ± 5.0 mL·kg−1·min−1 (all comparisons, p < 0.001. Furthermore, the incremental test resulted in a significantly higher VO2peak as compared to the 3-min test (p < 0.001. VO2peak was significantly higher on day 1 than day 2 for the 1-min test (p < 0.05 and displayed a trend toward higher values on day 2 for the incremental test (p = 0.07. High and very high ICCs across all physiological parameters were found for the 1-min (0.827–0.956, the 3-min (0.916–0.949, and the incremental test (0.728–0.956. The SDC was consistently small for HR (1-min: 4%, 3-min: 4%, incremental: 3%, moderate for absolute and body-mass normalized VO2peak (1-min: 5%, 3-min: 6%, incremental: 7% and large for BLa (1-min: 20%, 3-min: 12%, incremental: 22%.Conclusions: Whereas both the 3-min and the incremental test display high relative reliability

  6. The restricted stochastic user equilibrium with threshold model: Large-scale application and parameter testing

    DEFF Research Database (Denmark)

    Rasmussen, Thomas Kjær; Nielsen, Otto Anker; Watling, David P.

    2017-01-01

    This paper presents the application and calibration of the recently proposed Restricted Stochastic User Equilibrium with Threshold model (RSUET) to a large-scale case-study. The RSUET model avoids the limitations of the well-known Stochastic User Equilibrium model (SUE) and the Deterministic User...... equilibrated set of paths which all are within a threshold relative to the cost on the cheapest path and which do not leave any attractive paths unused. Several variants of a generic RSUET solution algorithm are tested and calibrated on a large-scale case network with 18,708 arcs and about 20 million OD......-pairs, and comparisons are performed with respect to a previously proposed RSUE model as well as an existing link-based mixed Multinomial Probit (MNP) SUE model. The results show that the RSUET has very attractive computation times for large-scale applications and demonstrate that the threshold addition to the RSUE...

  7. Estimation Source Parameters of Large-Scale Chemical Surface Explosions and Recent Underground Nuclear Tests

    Science.gov (United States)

    Gitterman, Y.; Kim, S.; Hofstetter, R.

    2013-12-01

    the both North Korea tests was estimated ~2 km, different from the value ~1 km informed by USGS. This depth estimation is based only on several closely placed teleseismic ISN stations and should be verified at other local networks on similar directions and distances from the test site.

  8. Evaluation of hypercoagulability in obese children with thrombin generation test and microparticle release: effect of metabolic parameters.

    Science.gov (United States)

    Siklar, Zeynep; Öçal, Gönül; Berberoğlu, Merih; Hacihamdioğlu, Bülent; Savas Erdeve, Senay; Eğin, Yonca; Akar, Nejat

    2011-01-01

    Obesity is associated with a hypercoagulable state. Thrombin generation test (TGT) and microparticle levels were not studied in obese children extensively. It is aimed to determine whether any differences in the coagulation system between obese and normal weighed children exist with the use of TGT and microparticles release. A total of 120 obese and 38 healthy children were included to the study. An increase of thrombin generation and microparticles levels were found in obese children. Hyperinsulinism could not find a risk factor for hypercoagulability in our obese children. None of the parameters of TGT has been shown to be related to metabolic parameters and metabolic syndrome. Microparticles release time is found to correlate only to body mass index (BMI) Standard deviation score (SDS) in obese children. Hypercoagulability is associated with childhood obesity. Significant correlation between degree of obesity and microparticles release suggested that high adipokine levels secreted from adipose tissue can stimulate procoagulant status-independent metabolic dearrangements.

  9. Two-phase flow patterns recognition and parameters estimation through natural circulation test loop image analysis

    Energy Technology Data Exchange (ETDEWEB)

    Mesquita, R.N.; Libardi, R.M.P.; Masotti, P.H.F.; Sabundjian, G.; Andrade, D.A.; Umbehaun, P.E.; Torres, W.M.; Conti, T.N.; Macedo, L.A. [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil). Nuclear Engineering Center], e-mail: rnavarro@ipen.br

    2009-07-01

    Visualization of natural circulation test loop cycles is used to study two-phase flow patterns associated with phase transients and static instabilities of flow. Experimental studies on natural circulation flow were originally related to accidents and transient simulations relative to nuclear reactor systems with light water refrigeration. In this regime, fluid circulation is mainly caused by a driving force ('thermal head') which arises from density differences due to temperature gradient. Natural circulation phenomenon has been important to provide residual heat removal in cases of 'loss of pump power' or plant shutdown in nuclear power plant accidents. The new generation of compact nuclear reactors includes natural circulation of their refrigerant fluid as a security mechanism in their projects. Two-phase flow patterns have been studied for many decades, and the related instabilities have been object of special attention recently. Experimental facility is an all glass-made cylindrical tubes loop which contains about twelve demineralized water liters, a heat source by an electrical resistor immersion heater controlled by a Variac, and a helicoidal heat exchanger working as cold source. Data is obtained through thermo-pairs distributed over the loop and CCD cameras. Artificial intelligence based algorithms are used to improve (bubble) border detection and patterns recognition, in order to estimate and characterize, phase transitions patterns and correlate them with the periodic static instability (chugging) cycle observed in this circuit. Most of initial results show good agreement with previous numerical studies in this same facility. (author)

  10. A Cross-Sectional Survey of HIV Testing and Prevalence in Twelve Brazilian Correctional Facilities.

    Science.gov (United States)

    Sgarbi, Renata Viebrantz Enne; Carbone, Andrea da Silva Santos; Paião, Dayse Sanchez Guimarães; Lemos, Everton Ferreira; Simionatto, Simone; Puga, Marco Antonio Moreira; Motta-Castro, Ana Rita Coimbra; Pompilio, Mauricio Antonio; Urrego, Juliana; Ko, Albert I; Andrews, Jason R; Croda, Julio

    2015-01-01

    Prior studies have reported higher HIV prevalence among prisoners than the general population in Brazil, but data have been derived from single prisons. The aim of this study was to evaluate HIV testing practices, prevalence and linkage to care among inmates in a network of 12 prisons. We administered a questionnaire to a population-based sample of inmates from 12 prisons in Central-West Brazil and collected sera for HIV and syphilis testing from January to December 2013. We evaluated factors associated with HIV testing and infection using multivariable logistic regression models. Six months after HIV testing, we assessed whether each HIV-infected prisoner was engaged in clinical care and whether they had started antiretroviral therapy. We recruited 3,362 inmates, of whom 2,843 (85%) were men from 8 prisons, and 519 (15%) were women from 4 prisons. Forty-five percent of participants reported never having been tested for HIV previously. In multivariable analysis, the variables associated with previous HIV testing were lack of a stable partner (adjusted odds ratio [AOR]: 1.38; 95% CI: 1.18-1.60), completed more than four years of schooling (AOR 1.40; 95% CI: 1.20-1.64), history of previous incarceration (AOR: 1.68; 95% CI: 1.43-1.98), history of mental illness (AOR 1.52; 95% CI: 1.31-1.78) and previous surgery (AOR 1.31; 95% CI: 1.12-1.52). Fifty-four (1.6%) of all participants tested positive for HIV; this included 44 (1.54%) men and 10 (1.92%) women. Among male inmates, HIV infection was associated with homosexuality (AOR 6.20, 95% CI: 1.73-22.22), self-report of mental illness (AOR 2.18, 95% CI: 1.13-4.18), history of sexually transmitted infections (AOR 3.28, 95% CI: 1.64-6.56), and syphilis sero-positivity (AOR 2.54, 95% CI: 1.20-5.39). Among HIV-infected individuals, 34 (63%) were unaware of their HIV status; only 23 of these 34 (68%) newly diagnosed participants could be reached at six month follow-up, and 21 of 23 (91%) were engaged in HIV care. HIV testing

  11. A Cross-Sectional Survey of HIV Testing and Prevalence in Twelve Brazilian Correctional Facilities.

    Directory of Open Access Journals (Sweden)

    Renata Viebrantz Enne Sgarbi

    Full Text Available Prior studies have reported higher HIV prevalence among prisoners than the general population in Brazil, but data have been derived from single prisons. The aim of this study was to evaluate HIV testing practices, prevalence and linkage to care among inmates in a network of 12 prisons.We administered a questionnaire to a population-based sample of inmates from 12 prisons in Central-West Brazil and collected sera for HIV and syphilis testing from January to December 2013. We evaluated factors associated with HIV testing and infection using multivariable logistic regression models. Six months after HIV testing, we assessed whether each HIV-infected prisoner was engaged in clinical care and whether they had started antiretroviral therapy.We recruited 3,362 inmates, of whom 2,843 (85% were men from 8 prisons, and 519 (15% were women from 4 prisons. Forty-five percent of participants reported never having been tested for HIV previously. In multivariable analysis, the variables associated with previous HIV testing were lack of a stable partner (adjusted odds ratio [AOR]: 1.38; 95% CI: 1.18-1.60, completed more than four years of schooling (AOR 1.40; 95% CI: 1.20-1.64, history of previous incarceration (AOR: 1.68; 95% CI: 1.43-1.98, history of mental illness (AOR 1.52; 95% CI: 1.31-1.78 and previous surgery (AOR 1.31; 95% CI: 1.12-1.52. Fifty-four (1.6% of all participants tested positive for HIV; this included 44 (1.54% men and 10 (1.92% women. Among male inmates, HIV infection was associated with homosexuality (AOR 6.20, 95% CI: 1.73-22.22, self-report of mental illness (AOR 2.18, 95% CI: 1.13-4.18, history of sexually transmitted infections (AOR 3.28, 95% CI: 1.64-6.56, and syphilis sero-positivity (AOR 2.54, 95% CI: 1.20-5.39. Among HIV-infected individuals, 34 (63% were unaware of their HIV status; only 23 of these 34 (68% newly diagnosed participants could be reached at six month follow-up, and 21 of 23 (91% were engaged in HIV care.HIV testing

  12. 77 FR 15609 - Revocation of TSCA Section 4 Testing Requirements for Certain High Production Volume Chemical...

    Science.gov (United States)

    2012-03-16

    ...). Neither of these companies is, therefore, subject to HPV1. The third small importer, Chartkit Chemical Corporation, reported that it imported only a small amount of acetyl chloride after the effective date of HPV1..., chromosomal damage, and repeated-dose 28-day oral toxicity in rodents, making those test requirements for C.I...

  13. Normal inter-limb differences during the straight leg raise neurodynamic test: a cross sectional study

    Directory of Open Access Journals (Sweden)

    Boyd Benjamin S

    2012-12-01

    Full Text Available Abstract Background The straight leg raise (SLR neurodynamic test is commonly used to examine the sensitivity of the lower quarter nervous system to movement. Range of motion during the SLR varies considerably, due to factors such as age, sex and activity level. Knowing intra-individual, inter-limb differences may provide a normative measure that is not influenced by such demographic characteristics. This study aimed to determine normal asymmetries between limbs in healthy, asymptomatic individuals during SLR testing and the relationship of various demographic characteristics. Methods The limb elevation angle was measured using an inclinometer during SLR neurodynamic testing that involved pre-positioning the ankle in plantar flexion (PF/SLR and neutral dorsiflexion (DF/SLR. Phase 1 of the study included 20 participants where the ankle was positioned using an ankle brace replicating research testing conditions. Phase 2 included 20 additional participants where the ankle was manually positioned to replicate clinical testing conditions. Results The group average range of motion during PF/SLR was 57.1 degrees (SD: 16.8 degrees on the left and 56.7 degrees (SD: 17.2 degrees on the right while during DF/SLR the group average was 48.5 degrees (SD: 16.1 degrees on the left and 48.9 degrees (SD: 16.4 degrees on the right. The range of motion during SLR was moderately correlated to weight (−0.40 to −0.52, body mass index (−0.41 to −0.52, sex (0.40 to 0.42 and self-reported activity level (0.50 to 0.57. Intra-individual differences between limbs for range of motion during PF/SLR averaged 5.0 degrees (SD: 3.5 degrees (95% CI: 3.8 degrees, 6.1 degrees and during DF/SLR averaged 4.1 degrees (SD: 3.2 degrees (95% CI: 3.1 degrees, 5.1 degrees but were not correlated with any demographic characteristic. There were no significant differences between Phase 1 and Phase 2. Conclusions Overall range of motion during SLR was related to sex, weight, BMI and

  14. Correlation of magnesium intake with metabolic parameters, depression and physical activity in elderly type 2 diabetes patients: a cross-sectional study

    Directory of Open Access Journals (Sweden)

    Huang Jui-Hua

    2012-06-01

    Full Text Available Abstract Background Type 2 diabetes mellitus is a major global public health problem in the worldwide and is increasing in aging populations. Magnesium intake may be one of the most important factors for diabetes prevention and management. Low magnesium intake may exacerbate metabolic abnormalities. In this study, the relationships of magnesium intake with metabolic parameters, depression and physical activity in elderly patients with type 2 diabetes were investigated. Methods This cross-sectional study involved 210 type 2 diabetes patients aged 65 years and above. Participants were interviewed to obtain information on lifestyle and 24-hour dietary recall. Assessment of depression was based on DSM-IV criteria. Clinical variables measured included anthropometric measurements, blood pressure, and biochemical determinations of blood and urine samples. Linear regression was applied to determine the relationships of magnesium intake with nutritional variables and metabolic parameters. Results Among all patients, 88.6% had magnesium intake which was less than the dietary reference intake, and 37.1% had hypomagnesaemia. Metabolic syndromes and depression were associated with lower magnesium intake (p  0.05. A positive relationship was found between magnesium intake and HDL-cholesterol (p = 0.005. Magnesium intake was inversely correlated with triglyceride, waist circumference, body fat percent and body mass index (p p for trend = 0005. Waist circumference, body fat percentage, and body mass index were significantly lower with increase quartile of magnesium intake (p for trend p for trend  Conclusions The majority of elderly type 2 diabetes who have low magnesium intake may compound this deficiency with metabolic abnormalities and depression. Future studies should determine the effects of increased magnesium intake or magnesium supplementation on metabolic control and depression in elderly people with type 2 diabetes.

  15. Scaling Tests of the Cross Section for Deeply Virtual Compton Scattering

    CERN Document Server

    Munoz Camacho, C; Mazouz, M; Ferdi, C; Gavalian, G; Kuchina, E; Amarian, M; Aniol, K A; Beaumel, M; Benaoum, H; Bertin, P; Brossard, M; Chen, J P; Chudakov, E; Craver, B; Cusanno, F; De Jager, C W; Deur, A; Feuerbach, R; Fieschi, J M; Frullani, S; Garçon, M; Garibaldi, F; Gayou, O; Gilman, R; Gómez, J; Gueye, P; Guichon, P A M; Guillon, B; Hansen, O; Hayes, D; Higinbotham, D; Holmstrom, T; Hyde-Wright, C E; Ibrahim, H; Igarashi, R; Jiang, X; Jo, H S; Kaufman, L; Kelleher, A; Kolarkar, A; Kumbartzki, G; Laveissière, G; Le Rose, J J; Lindgren, R; Liyanage, N; Lu, H J; Margaziotis, D J; Meziani, Z E; McCormick, K; Michaels, R; Michel, B; Moffit, B; Monaghan, P; Nanda, S; Nelyubin, V V; Potokar, M; Qiang, Y; Ransome, R D; Real, J S; Reitz, B; Roblin, Y; Roche, J; Sabatie, F; Saha, A; Sirca, S; Slifer, K J; Solvignon, P; Subedi, R; Sulkosky, V; Ulmer, P E; Voutier, E; Wang, K; Weinstein, L B; Wojtsekhowski, B; Zheng, X; Zhu, L

    2006-01-01

    We present the first measurements of \\vec{e}p->epg cross section in the deep virtual Compton scattering (DVCS) regime and the valence quark region (x_{Bj}=0.36). From JLab E00-110, we extract the imaginary part of the Bethe-Heitler (BH)--DVCS interference terms, to order twist-3 for Q^2 = 1.5, 1.9, and 2.3 GeV^2, and the real part of the BH-DVCS interference terms at Q^2 = 2.3 GeV^2. We present the first model-independent measurement of linear combinations of generalized parton distributions (GPDs) and GPD integrals up to twist-3 approximation. The validity of this approximation is strongly supported by the absence of Q^2-variation of the extracted terms -- thereby constraining the size of higher twist contributions to our observables.

  16. Use of point-of-care tests among general practitioners: a cross-sectional study in Saxony, Germany.

    Science.gov (United States)

    Frese, Thomas; Steger, Kathleen; Deutsch, Tobias; Schmid, Gordian L; Sandholzer, Hagen

    2016-01-01

    There is little knowledge about the use of point-of-care (POC) tests among general practitioners (GPs). The aim of this study was to determine which POC tests are known and used by GPs and how they estimate the usefulness of those tests. The use of POC tests among GPs and university-associated general practitioners who teach undergraduates (GPTUs) was elucidated. Differences between GPs working in urban and rural areas were also investigated. The knowledge, utilisation and usefulness (as estimated by the responders) of 27 POC tests were assessed with a self-designed questionnaire in a random sample of GPs (n=244) and GPTUs (n=48) in Saxony, Germany. A total of 63 GPs and 31 GPTUs (response rates 26.5% and 64.6%, respectively) responded. No relevant difference between GPs and GPTUs was found. The GPs were familiar with 22.5±4.5 (mean ± standard deviation) of the laboratory parameters, the GPTUs with 22.9±4.3 (p=0.427). The amount of recognised POC tests was 11.6±4.9 vs 12.4±5.5 (GPs vs GPTUs; p=0.441). The amount of utilised POC tests was 5.5±2.3 vs 6.0±2.5 (GPs vs GPTUs; p=0.431). Rural GPs were familiar with more POC tests than urban GPs (mean number of tests (rural vs urban): 13.3±5.5 vs 10.6±4.4; p=0.011), but there was no difference in the amount of utilised POC tests. Twelve of the 27 POC tests were estimated as useful by more than 50% of the responders who answered this item. Only a limited number of rapid tests are estimated as useful and are used by GPs in Saxony.

  17. To test or not to test: a cross-sectional survey of the psychosocial determinants of self-testing for cholesterol, glucose, and HIV.

    NARCIS (Netherlands)

    Grispen, J.E.; Ronda, G.; Dinant, G.J.; Vries, N.K. de; Weijden, G.D.E.M. van der

    2011-01-01

    BACKGROUND: Although self-tests are increasingly available and widely used, it is not clear whether their use is beneficial to the users, and little is known concerning the determinants of self-test use. The aim of this study was to identify the determinants of self-test use for cholesterol,

  18. Cross-Sectional Evaluation of Periodontal Status and Microbiologic and Rheumatoid Parameters in a Large Cohort of Patients With Rheumatoid Arthritis.

    Science.gov (United States)

    Schmickler, Jan; Rupprecht, Annegret; Patschan, Susann; Patschan, Daniel; Müller, Gerhard A; Haak, Rainer; Mausberg, Rainer F; Schmalz, Gerhard; Kottmann, Tanja; Ziebolz, Dirk

    2017-04-01

    This study evaluates periodontal conditions and microbiologic findings and their influence on rheumatologic disease parameters in patients with rheumatoid arthritis (RA). One hundred and sixty-eight patients with RA were included. A healthy control group (HC, n = 168) was composed according to age, sex, and smoking habits. Rheumatologic data (duration of illness, Disease Activity Score 28, rheumatic factor [RF], anti-cyclic citrullinated peptide [aCCP], medications) were extracted from patients' records. Dental examination included: 1) dental findings (decayed, missing, and/or filled adult teeth [DMF-T] index); 2) gingival inflammation (papillary bleeding index [PBI]); and 3) periodontal status (probing depth [PD], attachment loss [AL]). Periodontal condition was classified as healthy/mild, moderate, or severe periodontitis. Subgingival biofilm was analyzed regarding 11 periodontopathogenic bacteria. Statistical analyses included: 1) Kolmogorov-Smirnov test; 2) Mann-Whitney U test; 3) Pearson χ2 test; 4) Kruskal-Wallis test; and 5) regression analysis; level of significance α = 5%. Mean DMF-T was significantly higher in patients with RA (19.3 ± 4.8) than in HC group (16.9 ± 5.8), especially owing to number of missing teeth (RA = 6.0 ± 5.4, HC = 3.1 ± 3.3; P <0.01). Patients with RA had a significantly higher proportion of increased PD (P <0.01) and AL compared with HC group (P <0.01). Moderate to severe periodontitis was noted in 98% of patients with RA and 82% of the HC group (P <0.01). RF-positive patients with RA suffered from worse periodontal conditions than RF-negative patients (P = 0.01). Age, PBI, and presence of Treponema denticola (P <0.03) are related to periodontal condition in patients with RA. Although not statistically significant, Porphyromonas gingivalis and Fusobacterium nucleatum occur in higher concentrations more often in aCCP-positive patients with RA (P = 0.06). Patients with RA had worse periodontal conditions than HC participants

  19. New approach to assess bioequivalence parameters using generalized gamma mixed-effect model (model-based asymptotic bioequivalence test).

    Science.gov (United States)

    Chen, Yuh-Ing; Huang, Chi-Shen

    2014-02-28

    In the pharmacokinetic (PK) study under a 2x2 crossover design that involves both the test and reference drugs, we propose a mixed-effects model for the drug concentration-time profiles obtained from subjects who receive different drugs at different periods. In the proposed model, the drug concentrations repeatedly measured from the same subject at different time points are distributed according to a multivariate generalized gamma distribution, and the drug concentration-time profiles are described by a compartmental PK model with between-subject and within-subject variations. We then suggest a bioequivalence test based on the estimated bioavailability parameters in the proposed mixed-effects model. The results of a Monte Carlo study further show that the proposed model-based bioequivalence test is not only better on maintaining its level but also more powerful for detecting the bioequivalence of the two drugs than the conventional bioequivalence test based on a non-compartmental analysis or the one based on a mixed-effects model with a normal error variable. The application of the proposed model and test is finally illustrated by using data sets in two PK studies. Copyright © 2013 John Wiley & Sons, Ltd.

  20. Test-retest reliability of echo intensity parameters in healthy Achilles tendons using a semi-automatic tracing procedure.

    Science.gov (United States)

    Schneebeli, Alessandro; Del Grande, Filippo; Vincenzo, Gabriele; Cescon, Corrado; Barbero, Marco

    2017-11-01

    To evaluate the test-retest reliability of the ultrasound echo intensity parameters on healthy Achilles tendon using a semi-automatic tracing procedure. Eighteen healthy volunteers participated. B-mode images were acquired in the transverse plane (mid-tendon; insertion) and used to analyze tendon echogenicity. Grayscale distribution of the pixels within the selected ROIs was represented as a histogram. Descriptive statistics of the grayscale distribution (mean, variance, skewness, kurtosis, and entropy) and parameters from the co-occurrence matrix (contrast, energy, and homogeneity) were calculated. Reliability of echo intensity parameters of the mid-Achilles tendon ranged from high to very high with an ICC 2.k of 0.94 for echogenicity, 0.87 for variance, 0.80 for skewness, 0.72 for kurtosis, 0.89 for entropy, 0.90 for contrast, 0.91 for energy, and 0.93 for homogeneity, while for tendon insertion they ranged from moderate to high with an ICC 2.k of 0.74 for echogenicity, 0.88 for variance, 0.75 for skewness, 0.55 for kurtosis, 0.87 for entropy, 0.70 for contrast, 0.77 for energy, and 0.56 for homogeneity. Ultrasound echo intensity is a reliable technique to characterize the internal structure of the Achilles tendon.

  1. Testing life history predictions in a long-lived seabird: A population matrix approach with improved parameter estimation

    Science.gov (United States)

    Doherty, P.F.; Schreiber, E.A.; Nichols, J.D.; Hines, J.E.; Link, W.A.; Schenk, G.A.; Schreiber, R.W.

    2004-01-01

    Life history theory and associated empirical generalizations predict that population growth rate (λ) in long-lived animals should be most sensitive to adult survival; the rates to which λ is most sensitive should be those with the smallest temporal variances; and stochastic environmental events should most affect the rates to which λ is least sensitive. To date, most analyses attempting to examine these predictions have been inadequate, their validity being called into question by problems in estimating parameters, problems in estimating the variability of parameters, and problems in measuring population sensitivities to parameters. We use improved methodologies in these three areas and test these life-history predictions in a population of red-tailed tropicbirds (Phaethon rubricauda). We support our first prediction that λ is most sensitive to survival rates. However the support for the second prediction that these rates have the smallest temporal variance was equivocal. Previous support for the second prediction may be an artifact of a high survival estimate near the upper boundary of 1 and not a result of natural selection canalizing variances alone. We did not support our third prediction that effects of environmental stochasticity (El Niño) would most likely be detected in vital rates to which λ was least sensitive and which are thought to have high temporal variances. Comparative data-sets on other seabirds, within and among orders, and in other locations, are needed to understand these environmental effects.

  2. Design and Development of a Deep Acoustic Lining for the 40-by 80-Foot Wind Tunnel Test Section

    Science.gov (United States)

    Soderman, Paul T.; Schmitz, Fredric H.; Allen, Christopher S.; Jaeger, Stephen M.; Sacco, Joe N.; Mosher, Marianne; Hayes, Julie A.

    2002-01-01

    The work described in this report has made effective use of design teams to build a state-of-the-art anechoic wind-tunnel facility. Many potential design solutions were evaluated using engineering analysis, and computational tools. Design alternatives were then evaluated using specially developed testing techniques, Large-scale coupon testing was then performed to develop confidence that the preferred design would meet the acoustic, aerodynamic, and structural objectives of the project. Finally, designs were frozen and the final product was installed in the wind tunnel. The result of this technically ambitious project has been the creation of a unique acoustic wind tunnel. Its large test section (39 ft x 79 ft x SO ft), potentially near-anechoic environment, and medium subsonic speed capability (M = 0.45) will support a full range of aeroacoustic testing-from rotorcraft and other vertical takeoff and landing aircraft to the take-off/landing configurations of both subsonic and supersonic transports.

  3. Analysis of parameters for the automatic computation of the tear film break-up time test based on CCLRU standards.

    Science.gov (United States)

    Ramos, L; Barreira, N; Mosquera, A; Penedo, M G; Yebra-Pimentel, E; García-Resúa, C

    2014-03-01

    Dry eye syndrome is affecting a remarkable percentage of population. The prevalence is 10-15% of normal population, and 18-30% of contact lenses users. The break-up time (BUT) is a clinical test used for the diagnosis of this disease. In this work, we perform an analysis of parameters for a global and a local automatic computation of the BUT measure, based on criteria of specificity and sensitivity. We have tested our methodology on a dataset composed of 18 videos annotated by 4 different experts. The local analysis preserves the results of the global approach providing useful additional information about the break-up tear zone. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  4. Desire for predictive testing for Alzheimer's disease and impact on advance care planning: a cross-sectional study.

    Science.gov (United States)

    Sheffrin, Meera; Stijacic Cenzer, Irena; Steinman, Michael A

    2016-12-13

    It is unknown whether older adults in the United States would be willing to take a test predictive of future Alzheimer's disease, or whether testing would change behavior. Using a nationally representative sample, we explored who would take a free and definitive test predictive of Alzheimer's disease, and examined how using such a test may impact advance care planning. A cross-sectional study within the 2012 Health and Retirement Study of adults aged 65 years or older asked questions about a test predictive of Alzheimer's disease (N = 874). Subjects were asked whether they would want to take a hypothetical free and definitive test predictive of future Alzheimer's disease. Then, imagining they knew they would develop Alzheimer's disease, subjects rated the chance of completing advance care planning activities from 0 to 100. We classified a score > 50 as being likely to complete that activity. We evaluated characteristics associated with willingness to take a test for Alzheimer's disease, and how such a test would impact completing an advance directive and discussing health plans with loved ones. Overall, 75% (N = 648) of the sample would take a free and definitive test predictive of Alzheimer's disease. Older adults willing to take the test had similar race and educational levels to those who would not, but were more likely to be ≤75 years old (odds ratio 0.71 (95% CI 0.53-0.94)). Imagining they knew they would develop Alzheimer's, 81% would be likely to complete an advance directive, although only 15% had done so already. In this nationally representative sample, 75% of older adults would take a free and definitive test predictive of Alzheimer's disease. Many participants expressed intent to increase activities of advance care planning with this knowledge. This confirms high public interest in predictive testing for Alzheimer's disease and suggests this may be an opportunity to engage patients in advance care planning discussions.

  5. Scaling Tests of the Cross Section for Deeply Virtual Compton Scattering

    Energy Technology Data Exchange (ETDEWEB)

    Carlos Munoz Camacho; Alexandre Camsonne; Malek Mazouz; Catherine Ferdi; Gagik Gavalian; Elena Kuchina; Moscov Amaryan; Konrad Aniol; Matthieu Beaumel; Hachemi Benaoum; Pierre Bertin; Michel Brossard; Jian-Ping Chen; Eugene Chudakov; Brandon Craver; Francesco Cusanno; Kees de Jager; Alexandre Deur; Robert Feuerbach; Jean Fieschi; Salvatore Frullani; Michel Garcon; Franco Garibaldi; Olivier Gayou; Ronald Gilman; Javier Gomez; Paul Gueye; Pierre Guichon; Benoit Guillon; Jens-ole Hansen; David Hayes; Douglas Higinbotham; Timothy Holmstrom; Charles Hyde-Wright; Hassan Ibrahim; Ryuichi Igarashi; Xiaodong Jiang; Hyon-Suk Jo; Lisa Kaufman; Aidan Kelleher; Ameya Kolarkar; Gerfried Kumbartzki; Geraud Laveissiere; John LeRose; Richard Lindgren; Nilanga Liyanage; Hai-jiang Lu; Demetrius Margaziotis; Zein-Eddine Meziani; Kathy McCormick; Robert Michaels; Bernard Michel; Bryan Moffit; Peter Monaghan; Sirish Nanda; Vladimir Nelyubin; Milan Potokar; Yi Qiang; Ronald Ransome; Jean-Sebastien Real; Bodo Reitz; Yves Roblin; Julie Roche; Franck Sabatie; Arunava Saha; Simon Sirca; Karl Slifer; Patricia Solvignon; Ramesh Subedi; Vincent Sulkosky; Paul Ulmer; Eric Voutier; Kebin Wang; Lawrence Weinstein; Bogdan Wojtsekhowski; Xiaochao Zheng; Lingyan Zhu

    2006-07-27

    We present the first measurements of {rvec e}p {yields} ep{gamma} cross section in the deep virtual Compton scattering (DVCS) regime and the valence quark region (x{sub Bj} = 0.36). From JLab E00-110, we extract the imaginary part of the Bethe-Heitler (BH)--DVCS interference terms, to order twist-3 for Q{sup 2} = 1.5, 1.9, and 2.3 GeV{sup 2}, and the real part of the BH-DVCS interference terms at Q{sup 2}2 = 2.3 GeV{sup 2}. We present the first model-independent measurement of linear combinations of generalized parton distributions (GPDs) and GPD integrals up to twist-3 approximation. The validity of this approximation is strongly supported by the absence of Q{sup 2}-variation of the extracted terms--thereby constraining the size of higher twist contributions to our observables.

  6. Effect Analysis of Geometric Parameters on Stainless Steel Stamping Multistage Pump by Experimental Test and Numerical Calculation

    Directory of Open Access Journals (Sweden)

    Chuan Wang

    2013-01-01

    Full Text Available In order to improve the efficiency of stainless steel stamping multistage pump, quadratic regression orthogonal test, hydraulic design, and computational fluid dynamics (CFD are used to analyze the effect of pump geometric parameters. Sixteen impellers are designed based on the quadratic regression orthogonal test, which have three factors including impeller outlet slope, impeller blade outlet stagger angle, and impeller blade outlet width. Through quadratic regression equation, the function relationship between efficiency values and three factors is established. The optimal combination of geometric parameters is found through the analysis of the regression equation. To further study the influence of blade thickness on the performance of multistage pump, numerical simulations of multistage pump with different blade thicknesses are carried out. The influence law of blade thickness on pump performance is built from the external characteristics and internal flow field. In conclusion, with the increase of blade thickness, the best efficiency point of the pump shifts to the small flow rate direction, and the vortex regions inside the pump at rated flow gradually increase, which is the main reason that pump efficiency decreases along with the increase of the blade thickness at rated flow.

  7. Influence of L-Carnitine on fitness and oxidative stress parameters in Trotter Horses subjected to Laval’s test

    Directory of Open Access Journals (Sweden)

    Adalberto Falaschini

    2010-01-01

    Full Text Available In the last few years, in addition to grain, the high energy requirements of racehorses have been met with dietary supplementsof vegetable oil, which may, however, represent an easily oxidisable substrate. Carnitine can be used to improvelipid metabolism. We evaluated the changes in performance and oxidative stress parameters measured in 4 trottersreceiving a diet containing soybean oil and L-Carnitine and subjected to two Standardized Exercise Tests (SET accordingto Laval’s protocol (3 hits at increasing speed at an interval of 30 days. Blood samples were taken at rest, just aftereach of the three hits, and at 10, 20 and 40 min after each test to determine lactic acid, glucose, Non-Esterified FattyAcid (NEFA, β-hydroxybutyrate, Reactive Oxygen metabolites (ROMs, Glutathione Peroxidase (GSH-Px, and SuperoxideDismutase (SOD. L-Carnitine influenced ROMs and SOD and resulted in a reduction in the oxidative stress parameters.Some indices of the fitness status also improved.

  8. The Effect of Two Different Cognitive Tests on Gait Parameters during Dual Tasks in Healthy Postmenopausal Women

    Directory of Open Access Journals (Sweden)

    Magdalena Hagner-Derengowska

    2016-01-01

    Full Text Available Introduction. The paper aims to evaluate the influence of two different demanding cognitive tasks on gait parameters using BTS SMART system analysis. Patients and Methods. The study comprised 53 postmenopausal women aged 64.5 ± 6.7 years (range: 47–79. For every subject, gait analysis using a BTS SMART system was performed in a dual-task study design under three conditions: (I while walking only (single task, (II walking while performing a simultaneous simple cognitive task (SCT (dual task, and (III walking while performing a simultaneous complex cognitive task (CCT (dual task. Time-space parameters of gait pertaining to the length of a single support phase, double support phase, gait speed, step length, step width, and leg swing speed were analyzed. Results. Performance of cognitive tests during gait resulted in a statistically significant prolongation of the left (by 7% and right (by 7% foot gait cycle, shortening of the length of steps made with the right extremity (by 4%, reduction of speed of swings made with the left (by 11% and right (by 8% extremity, and reduction in gait speed (by 6%. Conclusions. Performance of cognitive tests during gait changes its individual pattern in relation to the level of the difficulty of the task.

  9. Test Data on Intumescent Fire Protection for Structural Steel Sections in Thailand

    Directory of Open Access Journals (Sweden)

    Thanyawat Pothisiri

    2012-04-01

    Full Text Available Current fire safety regulations in Thailand require that primary structural steel components of buildings be protected to achieve a minimum of 3-hour fire-resistance rating. For steel roof structures, 1-hour or 2-hour fire-resistance ratings may be specified depending on the number of stories. The verification methods of fire-resistance ratings set forth in the regulations are ISO 834 and ASTM E119 standards. The current trend of fire protection system for steel structures is intumescent paint due to aesthetical reasons. However, the fire-resistance ratings attained by proprietary intumescent systems currently available in the market are inconclusive. It is therefore the aim of this paper to provide an insight of the fire-resistance ratings of different intumescent products based on the data collected from the fire tests conducted by the Fire Safety Research Center of Chulalongkorn University during the period of 2009 - 2011. A statistical analysis was also conducted to compare the test data with the fire-resistance ratings specified in the current fire safety regulations.

  10. Hydraulic impact end effector final test report. Automation and robotics section, ER/WM-AT Program

    Energy Technology Data Exchange (ETDEWEB)

    Couture, S.

    1994-02-18

    One tool being developed for dislodging and fragmenting the hard salt cake waste in the single-shell nuclear waste tanks at the Hanford Reservation near Richland, Washington, is the hydraulic impact end effector (HIEE). This total operates by discharging 11-in. slugs of water at ultrahigh pressures. The HIEE was designed, built, and initially tested in 1992. Work in 1993 included advanced developments of the HIEE to further investigate its fragmentation abilities and to determine more effective operating procedures. These tests showed that more fragmentation can be achieved by increasing the charge pressure of 40 kpsi to 55 kpsi and by the use of different operating procedures. The size of the material and the impact energy of the water slug fired from the HIEE are believed to be major factors in material fragmentation. The material`s ability to fracture also appears to depend on the distance a fracture or crack line must travel to a free surface. Thus, larger material is more difficult to fracture than smaller material. Discharge pressures of 40 kpsi resulted in little penetration or fracturing of the material. At 55 kpsi, however, the size and depth of the fractures increased. Nozzle geometry had a significant effect on fragment size and quantity. Fragmentation was about an order of magnitude greater when the HIEE was discharged into drilled holes rather than onto the material surface. Since surface shots tend to create craters, a multi-shot procedure, coupled with an advanced nozzle design, was used to drill (crater) deep holes into large material. With this procedure, a 600-lb block was reduced to smaller pieces without the use of any additional equipment. Through this advanced development program, the HIEE has demonstrated that it can quickly fragment salt cake material into small, easily removable fragments. The HIEE`s material fragmentation ability can be substantially increased through the use of different nozzle geometries and operating procedures.

  11. Justification of Selecting Ultrasonic Testing Parameters for Bundle and Impact Damage Detection in Carbon-Fiber Constructions

    Directory of Open Access Journals (Sweden)

    M. V. Grigoriev

    2015-01-01

    Full Text Available Features of manufacturing process and use of carbon fibre-reinforced plastics (CFRP define specific types of only their defects. Furthermore, the CFRP structure material and its properties considerably differ from those of the metal materials. Therefore, a relevant task is to conduct research to justify the selection of the ultrasonic testing parameters of these materials.Optimal parameters and recommendations on quality control of such materials were grounded in the course of experimental studies on samples made from the UTR1000-12-400P carbon fabric, based on the T700GC-12K yarn and the T-31 epoxy binder, filled with artificial defects to imitate the bundles of different size and the impact damage.It is shown that with increasing frequency of the ultrasonic oscillation propagating in the samples there is an increase both in damping and in SNR for artificial defects. In other words, on the one hand, the lower is the oscillation frequency, the less is a damping effect, but, on the other one, the higher is the frequency, the higher is the sensitivity control. It was found that the optimum frequencies for the ultrasonic test of CFRP are those in the vicinity of 5 MHz.Furthermore, to detect the small-sized defects it is advised to use an ultrasonic beam focus, which can be achieved using phased arrays.The most optimal method of ultrasonic testing to search for impact damage is a mirrorshadow method, which is based on the measurement of the amplitude of the bottom echo signal. It is shown that the amplitude of the bottom echo signal in defect-free zone is, in average, 14 dB higher than in the area with shock damage.

  12. Psychosocial determinants of HIV testing across stages of change in Spanish population: a cross-sectional national survey

    Directory of Open Access Journals (Sweden)

    Maria Jose Fuster-RuizdeApodaca

    2017-03-01

    Full Text Available Abstract Background The goal of this research is to study the psychosocial determinants of HIV-testing as a function of the decision or change stage concerning this health behavior. The determinants considered in the major ongoing health models and the stages contemplated in the Precaution Adoption Process Model are analysed. Methods A cross-sectional survey was administered to 1,554 people over 16 years of age living in Spain by a computer-assisted telephone interview (CATI. The sample design was randomised, with quotas of sex and age. The survey measured various psychosocial determinants of health behaviors considered in the main cognitive theories, the interviewees' stage of change concerning HIV-testing (lack of awareness, decision not to act, decision to act, action, maintenance, and abandonment, and the signal for the action of getting tested or the perceived barriers to being tested. Results Approximately two thirds of the population had not ever had the HIV test. The predominant stage was lack of awareness. The most frequently perceived barriers to testing were related to the health system and to the stigma. We also found that the psychosocial determinants studied differed depending on the respondents' stage of change. Perception of risk, perceived self-efficacy, proximity to people who had been tested, perceived benefits of knowing the diagnosis, and a positive instrumental and emotional attitude were positively associated with the decision and maintenance of testing behavior. However, unrealistic underestimation of the risk of HIV infection, stereotypes about the infection, and the perceived severity of HIV were associated with the decision not to be tested. Conclusions There are various sociocognitive and motivational profiles depending on people’s decision stage concerning HIV-testing. Knowing this profile may allow us to design interventions to influence the psychosocial determinants that characterise each stage of change.

  13. Semiquantitative fecal calprotectin test in postinfectious and non-postinfectious irritable bowel syndrome: cross-sectional study

    Directory of Open Access Journals (Sweden)

    Liliana-Elisabeta David

    Full Text Available CONTEXT AND OBJECTIVE:The presence of a certain degree of inflammation in the gut wall is now accepted in irritable bowel syndrome (IBS. Fecal calprotectin is considered to be a reliable test for detecting intestinal inflammation. Our aim was to assess the presence of inflammation in postinfectious IBS (PI-IBS, compared with non-postinfectious IBS (NPI-IBS. A secondary objective was to determine the usefulness of a rapid fecal calprotectin test in inflammatory bowel diseases (IBD.DESIGN AND SETTING:This was a cross-sectional study. Patients with IBS and IBD at a single tertiary gastroenterology center were prospectively included in this study.METHODS:116 patients with Rome III IBS score (76 females; 48 ± 12 years were investigated; 24 patients (15 females had PI-IBS. Intestinal inflammation was assessed using the semiquantitative fecal calprotectin test. The results were expressed as T1, T2 or T3 according to the severity of inflammation ( 60 μg/g. Using the same test, we evaluated 20 patients with IBD (12 males; 47 ± 13 years.RESULTS:None of the patients with IBS had a T2 or T3 positive test. Among PI-IBS patients, 33% had a T1 positive test. Among NPI-IBS patients, 9.8% had a T1 positive test, which was significantly different to PI-IBS. The calprotectin test was positive in all IBD patients: 80% with T3, 10% with T2 and 10% with T1.CONCLUSIONS:Using a semiquantitative test for fecal calprotectin, positive tests were more frequent in PI-IBS patients than in NPI-IBS patients.

  14. Psychosocial determinants of HIV testing across stages of change in Spanish population: a cross-sectional national survey.

    Science.gov (United States)

    Fuster-RuizdeApodaca, Maria Jose; Laguia, Ana; Molero, Fernando; Toledo, Javier; Arrillaga, Arantxa; Jaen, Angeles

    2017-03-07

    The goal of this research is to study the psychosocial determinants of HIV-testing as a function of the decision or change stage concerning this health behavior. The determinants considered in the major ongoing health models and the stages contemplated in the Precaution Adoption Process Model are analysed. A cross-sectional survey was administered to 1,554 people over 16 years of age living in Spain by a computer-assisted telephone interview (CATI). The sample design was randomised, with quotas of sex and age. The survey measured various psychosocial determinants of health behaviors considered in the main cognitive theories, the interviewees' stage of change concerning HIV-testing (lack of awareness, decision not to act, decision to act, action, maintenance, and abandonment), and the signal for the action of getting tested or the perceived barriers to being tested. Approximately two thirds of the population had not ever had the HIV test. The predominant stage was lack of awareness. The most frequently perceived barriers to testing were related to the health system and to the stigma. We also found that the psychosocial determinants studied differed depending on the respondents' stage of change. Perception of risk, perceived self-efficacy, proximity to people who had been tested, perceived benefits of knowing the diagnosis, and a positive instrumental and emotional attitude were positively associated with the decision and maintenance of testing behavior. However, unrealistic underestimation of the risk of HIV infection, stereotypes about the infection, and the perceived severity of HIV were associated with the decision not to be tested. There are various sociocognitive and motivational profiles depending on people's decision stage concerning HIV-testing. Knowing this profile may allow us to design interventions to influence the psychosocial determinants that characterise each stage of change.

  15. Practice Parameters for the Non-Respiratory Indications for Polysomnography and Multiple Sleep Latency Testing for Children

    Science.gov (United States)

    Aurora, R. Nisha; Lamm, Carin I.; Zak, Rochelle S.; Kristo, David A.; Bista, Sabin R.; Rowley, James A.; Casey, Kenneth R.

    2012-01-01

    Background: Although a level 1 nocturnal polysomnogram (PSG) is often used to evaluate children with non-respiratory sleep disorders, there are no published evidence-based practice parameters focused on the pediatric age group. In this report, we present practice parameters for the indications of polysomnography and the multiple sleep latency test (MSLT) in the assessment of non-respiratory sleep disorders in children. These practice parameters were reviewed and approved by the Board of Directors of the American Academy of Sleep Medicine (AASM). Methods: A task force of content experts was appointed by the AASM to review the literature and grade the evidence according to the American Academy of Neurology grading system. Recommendations For PSG and MSLT Use: PSG is indicated for children suspected of having periodic limb movement disorder (PLMD) for diagnosing PLMD. (STANDARD) The MSLT, preceded by nocturnal PSG, is indicated in children as part of the evaluation for suspected narcolepsy. (STANDARD) Children with frequent NREM parasomnias, epilepsy, or nocturnal enuresis should be clinically screened for the presence of comorbid sleep disorders and polysomnography should be performed if there is a suspicion for sleep-disordered breathing or periodic limb movement disorder. (GUIDELINE) The MSLT, preceded by nocturnal PSG, is indicated in children suspected of having hypersomnia from causes other than narcolepsy to assess excessive sleepiness and to aid in differentiation from narcolepsy. (OPTION) The polysomnogram using an expanded EEG montage is indicated in children to confirm the diagnosis of an atypical or potentially injurious parasomnia or differentiate a parasomnia from sleep-related epilepsy (OPTION) Polysomnography is indicated in children suspected of having restless legs syndrome (RLS) who require supportive data for diagnosing RLS. (OPTION) Recommendations Against PSG Use: Polysomnography is not routinely indicated for evaluation of children with sleep

  16. Effects of coffee, smoking, and alcohol on liver function tests: a comprehensive cross-sectional study.

    Science.gov (United States)

    Jang, Eun Sun; Jeong, Sook-Hyang; Hwang, Sung Ho; Kim, Hyun Young; Ahn, So Yeon; Lee, Jaebong; Lee, Sang Hyub; Park, Young Soo; Hwang, Jin Hyeok; Kim, Jin-Wook; Kim, Nayoung; Lee, Dong Ho

    2012-10-18

    Liver function tests (LFTs) can be affected by many factors and the proposed effects of coffee on LFT require a comprehensive evaluation. The aim of this study was to elucidate whether drinking coffee, smoking, or drinking alcohol have independent effects on LFTs in Korean health-check examinees. We used the responses of 500 health-check examinees, who had participated in a self-administered questionnaire survey about coffee, alcohol drinking, and smoking habits. Coffee consumption was closely related to male gender, high body mass index (BMI), alcohol drinking, and smoking. On univariable and multivariable analyses, drinking coffee lowered serum levels of total protein, albumin, and aspartate aminotransferases (AST). On multivariable analyses, smoking raised serum γ-glutamyl transferase (GGT) level and decreased serum protein and albumin levels, while alcohol drinking raised GGT level after adjustment for age, gender, regular medication, BMI, coffee and alcohol drinking amounts, and smoking. Coffee consumption, smoking, and alcohol drinking affect the individual components of LFT in different ways, and the above 3 habits each have an impact on LFTs. Therefore, their effects on LFTs should be carefully interpreted, and further study on the mechanism of the effects is warranted.

  17. Effects of coffee, smoking, and alcohol on liver function tests: a comprehensive cross-sectional study

    Directory of Open Access Journals (Sweden)

    Jang Eun

    2012-10-01

    Full Text Available Abstract Background Liver function tests (LFTs can be affected by many factors and the proposed effects of coffee on LFT require a comprehensive evaluation. The aim of this study was to elucidate whether drinking coffee, smoking, or drinking alcohol have independent effects on LFTs in Korean health-check examinees. Methods We used the responses of 500 health-check examinees, who had participated in a self-administered questionnaire survey about coffee, alcohol drinking, and smoking habits. Results Coffee consumption was closely related to male gender, high body mass index (BMI, alcohol drinking, and smoking. On univariable and multivariable analyses, drinking coffee lowered serum levels of total protein, albumin, and aspartate aminotransferases (AST. On multivariable analyses, smoking raised serum γ-glutamyl transferase (GGT level and decreased serum protein and albumin levels, while alcohol drinking raised GGT level after adjustment for age, gender, regular medication, BMI, coffee and alcohol drinking amounts, and smoking. Conclusions Coffee consumption, smoking, and alcohol drinking affect the individual components of LFT in different ways, and the above 3 habits each have an impact on LFTs. Therefore, their effects on LFTs should be carefully interpreted, and further study on the mechanism of the effects is warranted.

  18. Computer program TRACK_TEST for calculating parameters and plotting profiles for etch pits in nuclear track materials

    Science.gov (United States)

    Nikezic, D.; Yu, K. N.

    2006-01-01

    A computer program called TRACK_TEST for calculating parameters (lengths of the major and minor axes) and plotting profiles in nuclear track materials resulted from light-ion irradiation and subsequent chemical etching is described. The programming steps are outlined, including calculations of alpha-particle ranges, determination of the distance along the particle trajectory penetrated by the chemical etchant, calculations of track coordinates, determination of the lengths of the major and minor axes and determination of the contour of the track opening. Descriptions of the program are given, including the built-in V functions for the two commonly employed nuclear track materials commercially known as LR 115 (cellulose nitrate) and CR-39 (poly allyl diglycol carbonate) irradiated by alpha particles. Program summaryTitle of the program:TRACK_TEST Catalogue identifier:ADWT Program obtainable from:CPC Program Library, Queen's University of Belfast, N. Ireland Program summary URL:http://cpc.cs.qub.ac.uk/summaries/ADWT Computer:Pentium PC Operating systems:Windows 95+ Programming language:Fortran 90 Memory required to execute with typical data:256 MB No. of lines in distributed program, including test data, etc.: 2739 No. of bytes in distributed program, including test data, etc.:204 526 Distribution format:tar.gz External subprograms used:The entire code must be linked with the MSFLIB library Nature of problem: Fast heavy charged particles (like alpha particles and other light ions etc.) create latent tracks in some dielectric materials. After chemical etching in aqueous NaOH or KOH solutions, these tracks become visible under an optical microscope. The growth of a track is based on the simultaneous actions of the etchant on undamaged regions (with the bulk etch rate V) and along the particle track (with the track etch rate V). Growth of the track is described satisfactorily by these two parameters ( V and V). Several models have been presented in the past describing

  19. Family physicians' self-perceived importance of providing genetic test information to patients: a cross-sectional study from Slovenia.

    Science.gov (United States)

    Klemenc-Ketis, Zalika; Peterlin, Borut

    2014-03-17

    Management of patients with genetic problems, including provision of genetic testing, is increasingly becoming a part of primary health care. The aim of this study was to determine the family physicians' (FPs) self-perceived importance of providing genetic test information to their patients. This was an observational cross-sectional postal study in the whole population of Slovenian family physicians (N=950). Its main outcome measure was the perceived importance of providing genetic test information on each of 10 items on a 5-point Likert scale. There were 271 (27.1% response rate) FPs that completed the questionnaire, out of which 205 (75.6%) were women. Mean age of the sample was 45.5 ± 10.6 years. More than 90% of Slovene FPs felt that it was their professional duty to discuss genetic testing issues with their patients. They were particularly prone to discuss clinical implications of positive and negative test results, as well as giving the patients information about the risk of passing a mutation onto children. Most Slovene family physicians feel responsible and willing to offer and discuss genetic testing and implications with their patients. Additional education should be provided to empower them for this task.

  20. Prevalence of prior HIV testing and associated factors among MSM in Zhejiang Province, China: a cross-sectional study

    Directory of Open Access Journals (Sweden)

    Runhua Li

    2016-11-01

    Full Text Available Abstract Background Men who have sex with men (MSM have become one of high-risk population for human immunodeficiency virus (HIV infection, due to their multiple sex partners and unprotected anal intercourse. Promoting HIV testing is an effective strategy for the prevention and control of HIV infection. We assessed the factors associated with a prior HIV testing history, which could provide guidance for implementation of future HIV intervention programs. Methods A cross-sectional study was conducted in three cities of Zhejiang Province, namely, Hangzhou, Ningbo and Wenzhou, using respondent-driven sampling, between December 2013 and June 2014. A face-to-face questionnaire survey was employed to collect relevant information about HIV testing. Univariate and multivariate logistic regression analyses were used to identify the factors associated with a prior HIV testing history. Results The adjusted rate of prior HIV testing among MSM in Zhejiang Province was 55.9 %. The adjusted rates of HIV and syphilis infections among MSM in Zhejiang Province were 14.0 % and 11.4 %, respectively. A weighted multivariate analysis showed that MSM of older age were more likely to be tested, as were MSM with higher level of education, self-reported homosexuality and a higher frequency of receiving AIDS/sexually transmitted infections educational intervention in the past year. MSM with suicidal inclination and self-perceived lower possibility of HIV infection were less likely to report ever having undergone an HIV test. Conclusions The prevalence of prior HIV testing among MSM in Zhejiang Province, China is low. Effective and more frequent interventional measures should be adopted to improve risk awareness and psychosocial support for younger, less educated MSM, and to encourage more MSM to undergo HIV testing.

  1. Does diurnal variation affect the first trimester fetal aneuploidy screening test biochemical parameters of fetuses with normal nuchal translucency?

    Science.gov (United States)

    Karsli, Mehmet Fatih; Cakmak, Bulent; Seckin, Kerem Doga; Akkas Yilmaz, Elif; Akgul, Gurcan; Togrul, Cihan; Kucukozkan, Tuncay

    2016-01-01

    The purpose of this study was to investigate the effect of diurnal variation on biochemical results of first trimester aneuploidy screening test. A total of 2725 singleton pregnant female, who had normal fetal nuchal translucency (NT) thickness, were included in the study during this period. Individuals were divided into two groups according to the sampling time (morning group: 09:00-11:00 am and afternoon group: 02:00-04:00 pm). Hormonal parameters (free-beta human chorionic gonadotropin [free β-hCG] and pregnancy-associated plasma protein-A [PAPP-A] multiples of median [MoM] levels) of first trimester (11(+0)-13(+6) weeks) combined aneuploidy screening test were compared between morning and afternoon groups. PAPP-A MoM levels were significantly lower in the afternoon group when compared to the morning group (p = 0.001), whereas free β-hCG MoM levels were similar in the both groups (p = 0.392). Rate of high risk for Down syndrome (Combine risk >1/300) and amniocentesis ratio were found higher in the afternoon group than morning group, but there were no difference between groups for the number of fetuses with Down syndrome. Receiving the venous blood sample for first trimester aneuploidy screening test in the afternoon causes low PAPP-A MoM levels.

  2. Effects of the isostretching method on morphological parameters and on a set of motor tests in the elderly

    Directory of Open Access Journals (Sweden)

    Christina Cruz Cepeda

    2013-07-01

    Full Text Available Moderate intensity resistance training seems to be effective in providing significant improvements on strength, balance and function in the elderly. This study aimed to analyze the effect of a 12-week isostretching training on functional capacity and muscle architecture in elderly women. The sample included 25 volunteers (n = 25 divided into a control group (CG, n = 11, 62.3 ± 1.9 years old, 1.58 ± 0.06 m, 73.4 ± 1.4 kg that followed their physical activity habits and an experimental group (EG, n = 14, 64.2 ± 4.3 years, 1.56 ± 0.05 m, 74.2 ± 1.6 kg that was submitted to an isostretching program. The following assessments were used: Timed Up and Go-TUGT, Tinetti balance test and evaluation of morphological parameters through ultrasound imaging technique. The results showed that the EG improved (p <0.05 in both TUGT and Tinetti. In the morphologic parameters of the vastus lateralis muscle in the EG, we observed the following: mean increase of 3.6 mm in length issue relaxation (p <0.05, ES = 1.15; increase of 4.9 mm in isometric contraction (p <0.05; ES = 1.94; increase of 16% in the pennation angle in the relaxed condition (p <0.05; ES = 0.70; increase of 12% in isometric contraction (p <0.05; ES = 0.50; increase of 8% in thickness in the relaxed condition (p <0.05, EF = 0.52; and increase of 9% in isometric contraction (p <0.05, EF = 0.43. The GC did not show any significant changes. The isometric training through the isostretching method promoted changes in the morphological and muscle parameters and also improved the functional abilities in elderly women.

  3. The Effect of asafetida Gum Extract on Blood Parameters and Histopathology of Testes in Male Wistar Rat

    Directory of Open Access Journals (Sweden)

    A. Ayoubi

    2013-03-01

    Full Text Available Ferula (Ferula assafetida is a perennial plant which belongs to Umbelliferea family is grow in a wide range of arid and semi-arid regions in Iran. Ferulla assafetida contains compounds including coumarins and sesquiterpens that has been traditionally used to treat diseases such as nervous disorders, asthma, gastrointestinal disease and epilepsy.. Effects of asafetida gum extract on blood parameters and histopathology of testes in male Wistar rat were studied using 32 rats with the initial body weight of 252 ± 4.3 g which randomly divided into 4 groups of 8 rats each the animals were injected with normal saline (control, and 75, 150 and 300 milligram per kilogram (mg/kg body weight of asafetida gum extract respectively. The result showed that, 300mg/kg asafetida gum extract caused adverse effects on blood cholesterol, glucose, aspartate aminotransferase (AST and alanine transaminase (ALT concentration, while 75 mg/kg had positive effects on above-mentioned parameters. Serum testosterone significantly decreased by increasing the level of asafetida gum extract and 300 mg/kg group had the lowest serum testosterone concentration. The numbers of Leydig cell layers were suppressed in asafetida-treated animals in comparison with the control. In conclusion, therapeutic effects of asafetida gum extract are dose-dependent and the level 300 mg/kg caused adverse impacts on metabolites and reproductive performance in male Wistar rats. The refers more in vivo studies with bigger experiment population are required.

  4. Optimum absorption and aperture parameters for realistic coupled volume spaces determined from computational analysis and subjective testing results.

    Science.gov (United States)

    Bradley, David T; Wang, Lily M

    2010-01-01

    This project utilizes computational modeling to study the effects of varying two architectural parameters, absorption ratio and aperture size, in a realistic coupled volume concert hall. Coupled volumes have been shown to exhibit non-exponential sound energy decay profiles, referred to as double slope effect. A number of objective metrics (T30/T15, LDT/T10, decay ratio, and DeltaL) have been used to quantify the double slope effect of the profiles generated in the virtual hall. T30/T15 and LDT/T10 showed similar trends across all hall configurations, indicating decreasing double slope effect with increasing coupled volume absorption ratio for each aperture size, and producing highest values at a specific aperture size for each absorption ratio. Generally, LDT/T10 provides finer resolution than T30/T15 when analyzing the decay profiles in this study. Results from the two metrics derived from Bayesian analysis, decay ratio and DeltaL, seem less consistent. Subjective testing has also been conducted to determine the effect of varying the two architectural parameters in the hall, and multidimensional scaling analysis shows that, in general, listener preference is inversely proportional to the level of double slope effect, with the highest levels of preference occurring at low and medium levels of double slope effect. Recommended design guidelines for coupled volume halls are provided based on these computational and subjective results.

  5. Diagnostic accuracy of uriSed automated urine microscopic sediment analyzer and dipstick parameters in predicting urine culture test results.

    Science.gov (United States)

    Huysal, Kağan; Budak, Yasemin U; Karaca, Ayse Ulusoy; Aydos, Murat; Kahvecioğlu, Serdar; Bulut, Mehtap; Polat, Murat

    2013-01-01

    Urinary tract infection (UTI) is one of the most common types of infection. Currently, diagnosis is primarily based on microbiologic culture, which is time- and labor-consuming. The aim of this study was to assess the diagnostic accuracy of urinalysis results from UriSed (77 Electronica, Budapest, Hungary), an automated microscopic image-based sediment analyzer, in predicting positive urine cultures. We examined a total of 384 urine specimens from hospitalized patients and outpatients attending our hospital on the same day for urinalysis, dipstick tests and semi-quantitative urine culture. The urinalysis results were compared with those of conventional semiquantitative urine culture. Of 384 urinary specimens, 68 were positive for bacteriuria by culture, and were thus considered true positives. Comparison of these results with those obtained from the UriSed analyzer indicated that the analyzer had a specificity of 91.1%, a sensitivity of 47.0%, a positive predictive value (PPV) of 53.3% (95% confidence interval (CI) = 40.8-65.3), and a negative predictive value (NPV) of 88.8% (95% CI = 85.0-91.8%). The accuracy was 83.3% when the urine leukocyte parameter was used, 76.8% when bacteriuria analysis of urinary sediment was used, and 85.1% when the bacteriuria and leukocyturia parameters were combined. The presence of nitrite was the best indicator of culture positivity (99.3% specificity) but had a negative likelihood ratio of 0.7, indicating that it was not a reliable clinical test. Although the specificity of the UriSed analyzer was within acceptable limits, the sensitivity value was low. Thus, UriSed urinalysis resuIts do not accurately predict the outcome of culture.

  6. Numerical analysis on inlet and outlet sections of a test fuel assembly for a Supercritical Water Reactor

    Energy Technology Data Exchange (ETDEWEB)

    Kiss, Attila, E-mail: kissa@reak.bme.hu; Vágó, Tamás; Aszódi, Attila

    2015-12-15

    Graphical abstract: - Highlights: • SCWR-FQT, first facility works with nuclear fuel cooled by SCW, was analysed. • The inlet and outlet section of the test fuel assembly was investigated by CFD. • Two thermohydraulic problems were revealed, described and analysed. • To solve them design changes were proposed and proven by further analysis. - Abstract: The Supercritical Water Reactor (SCWR) is one of the six reactor concepts being investigated under the framework of the Generation IV International Forum (GIF). One of the major challenges in the development of a SCWR is to develop materials for the fuel and core structures that will be sufficiently corrosion-resistant to withstand supercritical water conditions. Previously, core, reactor and plant design concept of the European High Performance Light Water Reactor (HPLWR) have been worked out in substantial detail. As the next step, it has been proposed to carry out a fuel qualification test of a small scale fuel assembly in a research reactor under typical prototype conditions. Therefore design and licensing of an experimental facility for the fuel qualification test, including the small scale fuel assembly with four fuel rods, the required coolant loop with supercritical water and safety and auxiliary systems, is the scope of the project “Supercritical Water Reactor—Fuel Qualification Test” (SCWR-FQT). This project is a collaborative project co-funded by the European Commission, which takes advantage of a Chinese—European collaboration. As a sub-task of the SCWR-FQT project, the geometry of inlet and outlet sections of the fuel assembly has to be investigated and optimized according to thermohydraulic considerations such as expected stable and uniform inflow pattern and uniform outflow temperature field conditions. To accomplish this task three dimensional CFD analysis has been performed. During the analysis two main problems were identified. On the one hand, generation of a huge eddy was

  7. Non-invasive prenatal testing for trisomy 21: a cross-sectional survey of service users' views and likely uptake.

    Science.gov (United States)

    Lewis, C; Hill, M; Silcock, C; Daley, R; Chitty, L S

    2014-04-01

    To assess the views and likely uptake of non-invasive prenatal testing (NIPT) for trisomy 21 among potential service users in the UK. Cross-sectional survey. Four antenatal clinics in England and two websites. A total of 1131 women and partners. Questionnaire conducted with women (and partners) recruited through antenatal clinics, a random sample of members of the website Mumsnet, and viewers of the website and Facebook page of the support group Antenatal Results and Choices (ARC). Factors impacting decision-making towards prenatal testing; views on NIPT, including service delivery and likely uptake; hypothetical scenarios, focused on current screening, invasive testing, and NIPT offered to women with a high-risk screening result. The vast majority (95.7%; 1071/1119; 95% CI 94.4-96.8%) thought NIPT was a positive development in prenatal care, with 88.2% (972/1103; 95% CI 86.1-90%) indicating that they would use the test, including respondents who would currently decline trisomy 21 screening (P < 0.001). Of the respondents who would have NIPT, 30.7% (299/973; 95% CI = 27.8-33.7%) said that they were 'likely' to terminate an affected pregnancy (including those who would currently decline screening or invasive testing), and 36.5% (355/973; 95% CI 33.5-39.6%) were 'not likely' to terminate an affected pregnancy. Respondents overwhelmingly indicated that safety for the baby was the most important attribute of NIPT (70.1%; 712/1015; 95% CI 67.2-73%). Respondents were overwhelmingly positive towards the introduction of NIPT. Uptake is likely to be high, and includes women who currently decline screening as well as those who will use the test for information only. Pre-test counselling to ensure that women understand the implications of the test result is essential. © 2014 Royal College of Obstetricians and Gynaecologists.

  8. Heat transfer results and operational characteristics of the NASA Lewis Research Center hot section cascade test facility

    Science.gov (United States)

    Gladden, H. J.; Yeh, F. C.; Fronek, D. L.

    1985-03-01

    The NASA Lewis Research Center gas turbine hot section test facility has been developed to provide a real-engine environment with well known boundary conditions for the aerothermal performance evaluation/verification of computer design codes. The initial aerothermal research data obtained are presented and the operational characteristics of the facility are discussed. This facility is capable of testing at temperatures and pressures up to 1600 K and 18 atm which corresponds to a vane exit Reynolds number range of 0.5 x 1 million to 2.5 x 1 million based on vane chord. The component cooling air temperature can be independently modulated between 330 and 700 K providing gas-to-coolant temperature ratios similar to current engine application. Research instrumentation of the test components provide conventional pressure and temperature measurements as well as metal temperatures measured by IR-photography. The primary data acquisition mode is steady state through a 704 channel multiplexer/digitizer. The test facility was configured as an annular cascade of full coverage film cooled vanes for the initial series of research tests.

  9. A cross-sectional study of the association between mobility test performance and personality among older adults.

    Science.gov (United States)

    Agmon, Maayan; Armon, Galit

    2016-05-18

    Falls among the elderly are a major public health challenge. The Timed-Up and Go (TUG) test is commonly used to identify older adults with mobility limitations. This study explored the association between TUG test results and personality among community-dwelling older adults. This cross-sectional study included 85 older adults. Personality was evaluated with the Five Factor Model. Times to complete the TUG as a single task (TUGST) alone and also with an additional cognitive task i.e., dual-task (DT), were recorded. Ordinary least squares OLS regression models were used to examine the associations between personality factors and both single DT TUG. Extraversion was found to be inversely associated with time to complete the TUGST (β = -.26, p personality and the TUG test. Specifically, older adults with high Extraversion completed the TUGST test more quickly than those who had lower measures of this trait and, people with high Conscientiousness completed the TUGDT tests more quickly. These findings may contribute to early identification of older adults at higher risk from mobility limitations and falls, and to developing personality-tailored interventions for fall prevention.

  10. Reduction of cross section area at fracture in tensile test: measurement and applications for flat sheet steels

    Science.gov (United States)

    Larour, P.; Freudenthaler, J.; Weissböck, T.

    2017-09-01

    This contribution deals with the use of maximum thinning and reduction of sample cross section area at fracture after tensile testing and applications for industrial flat sheet steels. Although included in all usual tensile testing standards, this mechanical property (“Z-value”) has long been neglected for flat sheet materials. It happens however to include some most valuable information on local ductility at fracture of sheet steels. This is increasingly needed for a more suitable description and ranking of newly developed advanced high strength sheet steels with regard to local ductility (stretch-flangeability, bendability, crash-ability) versus global ductility (deep-drawability). It is shown in this investigation that the ISO16630 punched and milled hole expansion ratio correlates linearly with the relative thickness reduction at fracture. A classification of cold rolled AHSS-UHSS sheet steels is attempted by plotting the relative thickness & area reduction at fracture vs. uniform and fracture elongation.

  11. Testing a self-determination theory model of children’s physical activity motivation: a cross-sectional study

    Science.gov (United States)

    2013-01-01

    Background Understanding children’s physical activity motivation, its antecedents and associations with behavior is important and can be advanced by using self-determination theory. However, research among youth is largely restricted to adolescents and studies of motivation within certain contexts (e.g., physical education). There are no measures of self-determination theory constructs (physical activity motivation or psychological need satisfaction) for use among children and no previous studies have tested a self-determination theory-based model of children’s physical activity motivation. The purpose of this study was to test the reliability and validity of scores derived from scales adapted to measure self-determination theory constructs among children and test a motivational model predicting accelerometer-derived physical activity. Methods Cross-sectional data from 462 children aged 7 to 11 years from 20 primary schools in Bristol, UK were analysed. Confirmatory factor analysis was used to examine the construct validity of adapted behavioral regulation and psychological need satisfaction scales. Structural equation modelling was used to test cross-sectional associations between psychological need satisfaction, motivation types and physical activity assessed by accelerometer. Results The construct validity and reliability of the motivation and psychological need satisfaction measures were supported. Structural equation modelling provided evidence for a motivational model in which psychological need satisfaction was positively associated with intrinsic and identified motivation types and intrinsic motivation was positively associated with children’s minutes in moderate-to-vigorous physical activity. Conclusions The study provides evidence for the psychometric properties of measures of motivation aligned with self-determination theory among children. Children’s motivation that is based on enjoyment and inherent satisfaction of physical activity is

  12. Testing a self-determination theory model of children's physical activity motivation: a cross-sectional study.

    Science.gov (United States)

    Sebire, Simon J; Jago, Russell; Fox, Kenneth R; Edwards, Mark J; Thompson, Janice L

    2013-09-26

    Understanding children's physical activity motivation, its antecedents and associations with behavior is important and can be advanced by using self-determination theory. However, research among youth is largely restricted to adolescents and studies of motivation within certain contexts (e.g., physical education). There are no measures of self-determination theory constructs (physical activity motivation or psychological need satisfaction) for use among children and no previous studies have tested a self-determination theory-based model of children's physical activity motivation. The purpose of this study was to test the reliability and validity of scores derived from scales adapted to measure self-determination theory constructs among children and test a motivational model predicting accelerometer-derived physical activity. Cross-sectional data from 462 children aged 7 to 11 years from 20 primary schools in Bristol, UK were analysed. Confirmatory factor analysis was used to examine the construct validity of adapted behavioral regulation and psychological need satisfaction scales. Structural equation modelling was used to test cross-sectional associations between psychological need satisfaction, motivation types and physical activity assessed by accelerometer. The construct validity and reliability of the motivation and psychological need satisfaction measures were supported. Structural equation modelling provided evidence for a motivational model in which psychological need satisfaction was positively associated with intrinsic and identified motivation types and intrinsic motivation was positively associated with children's minutes in moderate-to-vigorous physical activity. The study provides evidence for the psychometric properties of measures of motivation aligned with self-determination theory among children. Children's motivation that is based on enjoyment and inherent satisfaction of physical activity is associated with their objectively-assessed physical

  13. Behavioural linear standardized scoring system of the Lidia cattle breed by testing in herd: estimation of genetic parameters.

    Science.gov (United States)

    Pelayo, R; Solé, M; Sánchez, M J; Molina, A; Valera, M

    2016-10-01

    Docility is very important for cattle production, and many behavioural tests to measure this trait have been developed. However, very few objective behavioural tests to measure the opposite approach 'aggressive behaviour' have been described. Therefore, the aim of this work was to validate in the Lidia cattle breed a behavioural linear standardized scoring system that measure the aggressiveness and enable genetic analysis of behavioural traits expressing fearless and fighting ability. Reproducibility and repeatability measures were calculated for the 12 linear traits of this scoring system to assess its accuracy, and ranged from 85.3 and 94.2%, and from 66.7 to 97.9%, respectively. Genetic parameters were estimated using an animal model with a Bayesian approach. A total of 1202 behavioural records were used. The pedigree matrix contained 5001 individuals. Heritability values (with standard deviations) ranged between 0.13 (0.04) (Falls of the bull) and 0.41 (0.08) (Speed of approach to horse). Genetic correlations varied from 0.01 (0.07) to 0.90 (0.13). Finally, an exploratory factor analysis using the genetic correlation matrix was calculated. Three main factors were retained to describe the traditional genetic indexes aggressiveness, strength and mobility. © 2015 Blackwell Verlag GmbH.

  14. Setting accelerated dissolution test for PLGA microspheres containing peptide, investigation of critical parameters affecting drug release rate and mechanism.

    Science.gov (United States)

    Tomic, I; Vidis-Millward, A; Mueller-Zsigmondy, M; Cardot, J-M

    2016-05-30

    The objective of this study was development of accelerated in vitro release method for peptide loaded PLGA microspheres using flow-through apparatus and assessment of the effect of dissolution parameters (pH, temperature, medium composition) on drug release rate and mechanism. Accelerated release conditions were set as pH 2 and 45°C, in phosphate buffer saline (PBS) 0.02M. When the pH was changed from 2 to 4, diffusion controlled phases (burst and lag) were not affected, while release rate during erosion phase decreased two-fold due to slower ester bonds hydrolyses. Decreasing temperature from 45°C to 40°C, release rate showed three-fold deceleration without significant change in release mechanism. Effect of medium composition on drug release was tested in PBS 0.01M (200 mOsm/kg) and PBS 0.01M with glucose (380 mOsm/kg). Buffer concentration significantly affected drug release rate and mechanism due to the change in osmotic pressure, while ionic strength did not have any effect on peptide release. Furthermore, dialysis sac and sample-and-separate techniques were used, in order to evaluate significance of dissolution technique choice on the release process. After fitting obtained data to different mathematical models, flow-through method was confirmed as the most appropriate for accelerated in vitro dissolution testing for a given formulation. Copyright © 2016 Elsevier B.V. All rights reserved.

  15. Validation of a mathematical model for Bell 427 Helicopter using parameter estimation techniques and flight test data

    Science.gov (United States)

    Crisan, Emil Gabriel

    Certification requirements, optimization and minimum project costs, design of flight control laws and the implementation of flight simulators are among the principal applications of system identification in the aeronautical industry. This document examines the practical application of parameter estimation techniques to the problem of estimating helicopter stability and control derivatives from flight test data provided by Bell Helicopter Textron Canada. The purpose of this work is twofold: a time-domain application of the Output Error method using the Gauss-Newton algorithm and a frequency-domain identification method to obtain the aerodynamic and control derivatives of a helicopter. The adopted model for this study is a fully coupled, 6 degree of freedom (DoF) state space model. The technique used for rotorcraft identification in time-domain was the Maximum Likelihood Estimation method, embodied in a modified version of NASA's Maximum Likelihood Estimator program (MMLE3) obtained from the National Research Council (NRC). The frequency-domain system identification procedure is incorporated in a comprehensive package of user-oriented programs referred to as CIFERRTM. The coupled, 6 DoF model does not include the high frequency main rotor modes (flapping, lead-lag, twisting), yet it is capable of modeling rotorcraft dynamics fairly accurately as resulted from the model verification. The identification results demonstrate that MMLE3 is a powerful and effective tool for extracting reliable helicopter models from flight test data. The results obtained in frequency-domain approach demonstrated that CIFERRTM could achieve good results even on limited data.

  16. Identifying design parameters controlling damage behaviors of continuous fiber-reinforced thermoplastic composites using micromechanics as a virtual testing tool

    KAUST Repository

    Pulungan, Ditho Ardiansyah

    2017-03-31

    In this paper, we propose a micromechanical approach to predict damage mechanisms and their interactions in glass fibers/polypropylene thermoplastic composites. First, a representative volume element (RVE) of such materials was rigorously determined using a geometrical two-point probability function and the eigenvalue stabilization of homogenized elastic tensor obtained by Hill-Mandel kinematic homogenization. Next, the 3D finite element models of the RVE were developed accordingly. The fibers were modeled with an isotropic linear elastic material. The matrix was modeled with an isotropic linear elastic, rate-independent hyperbolic Drucker-Prager plasticity coupled with a ductile damage model that is able to show pressure dependency of the yield and damage behavior often found in a thermoplastic material. In addition, cohesive elements were inserted into the fiber-matrix interfaces to simulate debonding. The RVE faces are imposed with periodical boundary conditions to minimize the edge effect. The RVE was then subjected to transverse tensile loading in accordance with experimental tensile tests on [90]8 laminates. The model prediction was found to be in very good agreement with the experimental results in terms of the global stress-strain curves, including the linear and nonlinear portion of the response and also the failure point, making it a useful virtual testing tool for composite material design. Furthermore, the effect of tailoring the main parameters of thermoplastic composites is investigated to provide guidelines for future improvements of these materials.

  17. Community engagement in sexual health and uptake of HIV testing and syphilis testing among MSM in China: a cross-sectional online survey.

    Science.gov (United States)

    Zhang, Tiange P; Liu, Chuncheng; Han, Larry; Tang, Weiming; Mao, Jessica; Wong, Terrence; Zhang, Ye; Tang, Songyuan; Yang, Bin; Wei, Chongyi; Tucker, Joseph D

    2017-04-03

    HIV and syphilis testing rates remain low among men who have sex with men (MSM) in low- and middle-income countries (LMICs). Community engagement has been increasingly used to promote HIV testing among key populations in high-income countries, often in settings with stronger civil society. This study aimed to assess socio-demographic, behavioural, and community engagement factors associated with HIV and syphilis testing among MSM in China. MSM ≥16 years old who had condomless sex in the past three months were recruited nationwide to complete a cross-sectional online survey in November 2015. Data were collected on socio-demographics, sexual behaviours, HIV testing, syphilis testing, and community engagement in sexual health. We defined community engagement in sexual health using six items assessing awareness and advocacy of sexual health programmes. The underlying factor structure of a 6-item community engagement scale was determined through exploratory factor analysis. Univariate and multivariable logistic regressions identified correlates of HIV and syphilis testing. 1189 MSM were recruited. 54% (647/1189) of men had ever tested for HIV and 30% (354/1189) had ever tested for syphilis. Factor analysis suggested three levels of community engagement (minimal, moderate, and substantial) and this model explained 79.5% of observed variance. A quarter (26%, 312/1189) reported none to minimal engagement, over one half (54%, 644/1189) reported moderate engagement, and a fifth (20%, 233/1189) reported substantial engagement. Multivariable logistic regression showed that MSM with greater community engagement in sexual health were more likely to have ever tested for HIV (substantial vs. no engagement: aOR 7.91, 95% CI 4.98-12.57) and for syphilis (substantial vs. no engagement: aOR 5.35, 95% CI 3.16-9.04). HIV and syphilis testing are suboptimal among MSM in China. Community engagement may be useful for promoting testing in China and should be considered in intervention

  18. Experimental investigation of the two-phase flow regimes and pressure drop in horizontal mini-size rectangular test section

    Science.gov (United States)

    Elazhary, Amr Mohamed; Soliman, Hassan M.

    2012-10-01

    An experimental study was conducted in order to investigate two-phase flow regimes and fully developed pressure drop in a mini-size, horizontal rectangular channel. The test section was machined in the form of an impacting tee junction in an acrylic block (in order to facilitate visualization) with a rectangular cross-section of 1.87-mm height on 20-mm width on the inlet and outlet sides. Pressure drop measurement and flow regime identification were performed on all three sides of the junction. Air-water mixtures at 200 kPa (abs) and room temperature were used as the test fluids. Four flow regimes were identified visually: bubbly, plug, churn, and annular over the ranges of gas and liquid superficial velocities of 0.04 ≤ JG ≤ 10 m/s and 0.02 ≤ JL ≤ 0.7 m/s, respectively, and a flow regime map was developed. Accuracy of the pressure-measurement technique was validated with single-phase, laminar and turbulent, fully developed data. Two-phase experiments were conducted for eight different inlet conditions and various mass splits at the junction. Comparisons were conducted between the present data and former correlations for the fully developed two-phase pressure drop in rectangular channels with similar sizes. Wide deviations were found among these correlations, and the correlations that agreed best with the present data were identified.

  19. Is macrodispersivity a meaningful parameter? - Applicability of simple ADE-equation for modeling of a tracer test

    Science.gov (United States)

    Haendel, Falk; Liedl, Rudolf; Dietrich, Peter

    2015-04-01

    In the last decades, numerical modeling has been developed as the common method to investigate solute transport in groundwater. Thereby in science, various numerical procedures have been applied for understanding complex processes of transport in highly heterogeneous aquifers. Beside this, numerical modeling of transport is also standard practice in engineering and consulting. The numerical approaches differ due to factors such as scope of modeling, knowledge about site characterization and time and manpower constraints. In general, there is a lack of knowledge about the hydraulic properties of a site like information of lithology and deterministic subunits. Therefore, assumption have to be made and standard Advection-Dispersion-Equation (ADE) is used involving macrodispersion coefficients. In this study we analyze a tracer test in the Lauswiesen aquifer, Baden-Wuerttemberg, Germany, described in the literature by Ptak et al. (2004) and Riva et al. (2008) and use a straightforward numerical model to reproduce the integral and depth-dependent transport behavior. Depth-dependent tracer test data show a clear depth dependency including two different breakthrough behaviors. Previous model approaches for evaluation of the mentioned tracer test by Riva et al. (2008) included a large set of Monte-Carlo simulations by describing the aquifer heterogeneity by a double stochastic process. Information about the geostatistical parameters could be gained mainly by a large number of sieve analyses. Finally, stochastic modeling of Riva et al. (2008) created a large amount of breakthrough curves due to high uncertainty of the distribution of hydraulic conductivity. However, stochastic modeling and a precise reproduction of the variability of hydraulic properties in space help to better understand the transport processes driven by heterogeneity and to provide assessment of uncertainty at a site. In our straightforward modeling we include only two deterministic subunits, more

  20. A numerical study of two different specimen fixtures for the modified compact tension test – their influence on concrete fracture parameters

    Czech Academy of Sciences Publication Activity Database

    Holušová, Táňa; Seitl, Stanislav; Cifuentes, H.; Canteli, A.

    2016-01-01

    Roč. 10, č. 35 (2016), s. 242-249 ISSN 1971-8993 Institutional support: RVO:68081723 Keywords : Modified Compact Tension Test * Fracture Parameters * Cementitious Composites * FEM Subject RIV: JL - Materials Fatigue, Friction Mechanics

  1. Knowledge and perceptions of couples' voluntary counseling and testing in urban Rwanda and Zambia: a cross-sectional household survey.

    Directory of Open Access Journals (Sweden)

    April L Kelley

    2011-05-01

    Full Text Available Most incident HIV infections in sub-Saharan Africa occur between cohabiting, discordant, heterosexual couples. Though couples' voluntary HIV counseling and testing (CVCT is an effective, well-studied intervention in Africa, <1% of couples have been jointly tested.We conducted cross-sectional household surveys in Kigali, Rwanda (n = 600 and Lusaka, Zambia (n = 603 to ascertain knowledge, perceptions, and barriers to use of CVCT.Compared to Lusaka, Kigali respondents were significantly more aware of HIV testing sites (79% vs. 56%; had greater knowledge of HIV serodiscordance between couples (83% vs. 43%; believed CVCT is good (96% vs. 72%; and were willing to test jointly (91% vs. 47%. Stigma, fear of partner reaction, and distance/cost/logistics were CVCT barriers.Though most respondents had positive attitudes toward CVCT, the majority were unaware that serodiscordance between cohabiting couples is possible. Future messages should target gaps in knowledge about serodiscordance, provide logistical information about CVCT services, and aim to reduce stigma and fear.

  2. Factors associated with continuing emergence of β-thalassemia major despite prenatal testing: a cross-sectional survey.

    Science.gov (United States)

    Al Sabbah, Haleama; Khan, Sarah; Hamadna, Abdallah; Abu Ghazaleh, Lamia; Dudin, Anwar; Karmi, Bashar Adnan

    2017-01-01

    Health care initiatives focusing on prenatal testing and premarital genetic screening aiming to reduce the incidence of β-thalassemia have emerged during the last decade. In Palestine, 4% of the population are known thalassemia carriers with new cases continuing to appear despite the availability of prenatal testing. This study aims to identify factors that influence the decision to retain or abort fetuses affected by β-thalassemia in Palestine. Convenience sampling was used to select 32 women (72 fetuses) who were at risk of having a baby with β-thalassemia. A questionnaire on prenatal testing, test results, pregnancy outcomes, and factors influencing the decision to terminate the pregnancy were used for this cross-sectional study. The data were analyzed using SPSS version 17. Among the fetuses screened, 36 (50%) were thalassemia carriers and 20 (28%) had β-thalassemia; 17 (85%) affected fetuses were aborted. Religious beliefs were the most cited reason for opposing abortion while prior experience with β-thalassemia patients and awareness programs promoted abortions. Mothers who opted to retain an affected fetus had modest educational attainment. Higher educational level was significantly associated with the decision to abort an affected fetus (p<0.05). A religious consensus is needed on the abortion of fetuses affected by β-thalassemia. Improving female education and increasing awareness on thalassemia could help reduce the incidence of β-thalassemia in Palestine and around the world.

  3. Nationwide Cross-Sectional Study on Bovine Tuberculosis by Intra Vitam Testing in Germany, 2013-2014.

    Science.gov (United States)

    Menge, C; Köhler, H; Moser, I; Conraths, F J; Homeier, T

    2017-08-01

    Germany was declared officially free from bovine tuberculosis (bTB) effective from 1 July 1996. After the occurrence of several Mycobacterium (M.) bovis outbreaks in north-western Germany in recent years with high intraherd prevalence at the time of detection, the reliability of abattoir surveillance as the principal component of the national bTB control programme was debated by veterinary public health officials. Rising numbers of wildlife-associated outbreaks caused by M. caprae in southern Germany eventually prompted a nationwide cross-sectional study on bTB. A total of 51 999 cattle, that is 0.41% of the national herd kept on 1.73% of German cattle farms, were tested. Despite 4 positive and 152 inconclusive single intradermal comparative cervical test results, none of the animals was confirmed as bTB-positive by a subsequent interferon-release assay or by post-mortem PCR testing. The estimated prevalence of bTB in Germany was thus calculated as 0.0% (CI 0.0000-0.0064%) affirming that Germany still qualifies as an officially tuberculosis-free (OTF) country. Occasional randomized nationwide testing can be an appropriate tool to reassure the OTF status and may also help to maintain an appropriate training level for the diagnostic procedures and for supporting sustained disease awareness among stakeholders. © 2016 Blackwell Verlag GmbH.

  4. Work-related stress is associated with impaired neuropsychological test performance: a clinical cross-sectional study.

    Science.gov (United States)

    Eskildsen, Anita; Andersen, Lars Peter; Pedersen, Anders Degn; Vandborg, Sanne Kjær; Andersen, Johan Hviid

    2015-01-01

    Patients on sick leave due to work-related stress often complain about impaired concentration and memory. However, it is undetermined how widespread these impairments are, and which cognitive domains are most long-term stress sensitive. Previous studies show inconsistent results and are difficult to synthesize. The primary aim of this study was to examine whether patients with work-related stress complaints have cognitive impairments compared to a matched control group without stress. Our secondary aim was to examine whether the level of self-reported perceived stress is associated with neuropsychological test performance. We used a broad neuropsychological test battery to assess 59 outpatients with work-related stress complaints (without major depression) and 59 healthy controls. We matched the patients and controls pairwise by sex, age and educational level. Compared to controls, patients generally showed mildly reduced performance across all the measured domains of the neuropsychological test battery. However, only three comparisons reached statistical significance (p working memory. There were no statistical significant associations between self-reported perceived stress level and neuropsychological test performance. In conclusion, we recommend that cognitive functions should be considered when evaluating patients with work-related stress complaints, especially when given advice regarding return to work. Since this study had a cross-sectional design, it is still uncertain whether the impairments are permanent. Further study is required to establish causal links between work-related stress and cognitive deficits.

  5. HIV testing among men who have sex with men in Tijuana, Mexico: a cross-sectional study.

    Science.gov (United States)

    Pines, Heather A; Goodman-Meza, David; Pitpitan, Eileen V; Torres, Karla; Semple, Shirley J; Patterson, Thomas L

    2016-02-04

    HIV testing is critical to the delivery of comprehensive HIV prevention and care services, yet coverage of sexual minorities by HIV testing programmes remains insufficient in many low- and middle-income countries, including Mexico. The objective of this study was to identify the prevalence and correlates of HIV testing among men who have sex with men (MSM) in Tijuana, Mexico. We conducted a cross-sectional study (2012-2013) among 189 MSM recruited via respondent-driven sampling (RDS). RDS-weighted logistic regression was used to identify correlates of prior HIV testing. RDS-adjusted prevalence of prior and recent (≤ 12 months) HIV testing was 63.5% (95% CI 51.9% to 73.5%) and 36.8% (95% CI 25.4% to 46.4%), respectively. Prior HIV testing was positively associated with older age (adjusted OR (AOR)=1.09, 95% CI 1.04 to 1.15), being born in Tijuana (AOR=2.68, 95% CI 1.05 to 6.86), higher levels of education (AOR=2.65, 95% CI 1.08 to 6.53), identifying as homosexual or gay (AOR=3.73, 95% CI 1.48 to 9.42), being more 'out' about having sex with men (AOR=1.28, 95% CI:1.02 to 1.62), and a history of sexual abuse (AOR=3.24, 95% CI 1.06 to 9.86). Prior HIV testing was negatively associated with reporting more condomless anal intercourse acts (past 2 months) (AOR=0.95, 95% CI 0.92 to 0.98) and greater internalised homophobia (AOR=0.92, 95% CI 0.86 to 0.99). Our findings indicate an urgent need for expanded HIV testing services for MSM in Tijuana. Innovative, non-stigmatising, confidential HIV testing interventions targeted at young, less educated, migrant and non-gay identifying MSM may facilitate HIV testing and timely linkage to HIV care and treatment within this population. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://www.bmj.com/company/products-services/rights-and-licensing/

  6. Random regression models to estimate genetic parameters for test-day milk yield in Brazilian Murrah buffaloes.

    Science.gov (United States)

    Sesana, R C; Bignardi, A B; Borquis, R R A; El Faro, L; Baldi, F; Albuquerque, L G; Tonhati, H

    2010-10-01

    The objective of this work was to estimate covariance functions for additive genetic and permanent environmental effects and, subsequently, to obtain genetic parameters for buffalo's test-day milk production using random regression models on Legendre polynomials (LPs). A total of 17 935 test-day milk yield (TDMY) from 1433 first lactations of Murrah buffaloes, calving from 1985 to 2005 and belonging to 12 herds located in São Paulo state, Brazil, were analysed. Contemporary groups (CGs) were defined by herd, year and month of milk test. Residual variances were modelled through variance functions, from second to fourth order and also by a step function with 1, 4, 6, 22 and 42 classes. The model of analyses included the fixed effect of CGs, number of milking, age of cow at calving as a covariable (linear and quadratic) and the mean trend of the population. As random effects were included the additive genetic and permanent environmental effects. The additive genetic and permanent environmental random effects were modelled by LP of days in milk from quadratic to seventh degree polynomial functions. The model with additive genetic and animal permanent environmental effects adjusted by quintic and sixth order LP, respectively, and residual variance modelled through a step function with six classes was the most adequate model to describe the covariance structure of the data. Heritability estimates decreased from 0.44 (first week) to 0.18 (fourth week). Unexpected negative genetic correlation estimates were obtained between TDMY records at first weeks with records from middle to the end of lactation, being the values varied from -0.07 (second with eighth week) to -0.34 (1st with 42nd week). TDMY heritability estimates were moderate in the course of the lactation, suggesting that this trait could be applied as selection criteria in milking buffaloes. Copyright 2010 Blackwell Verlag GmbH.

  7. Factors associated with HIV testing among young men who have sex with men in Myanmar: a cross-sectional study.

    Science.gov (United States)

    Pham, Minh D; Aung, Poe Poe; Paing, Aye Kyawt; Pasricha, Naanki; Agius, Paul A; Tun, Waimar; Bajracharya, Ashish; Luchters, Stanley

    2017-11-01

    In Myanmar, men who have sex with men (MSM) experience high risk of HIV infection. However, access to HIV testing and prevention services remains a challenge among this marginalized population. The objective of this study was to estimate population prevalence and correlates of prior HIV testing among young MSM (YMSM) and informs the development of HIV testing and intervention programmes that respond to the specific needs of this population. Five hundred and eighty-five YMSM aged 18 to 24 years were recruited using respondent-driven sampling (RDS) in a cross-sectional survey conducted in six townships of Myanmar. RDS-adjusted population estimates were calculated to estimate prevalence of HIV testing; RDS-weighted logistic regression was used to examine correlates of HIV testing in the past 6 months and in a lifetime. There were 12 participants who reported receiving a HIV-positive test; of those, five were tested in the past 6 months. The RDS-weighted prevalence estimates of lifetime (any prior) HIV testing was 60.6% (95% CI: 53.3% to 66.4%) and of recent (≤ 6 months) HIV testing was 50.1% (95% CI: 44.1% to 55.5%). In multivariable analysis, sexual identity was associated with lifetime but not recent HIV testing. Lifetime and recent HIV testing were associated with having three or more male sexual partners in the past 12 months (adjusted ORs (aORs) = 2.28, 95% CIs: 1.21 to 4.32 and 2.69, 95% CI: 1.59 to 4.56), having good HIV-related knowledge (aORs = 1.96, 95% CIs: 1.11 to 3.44 and 1.77, 95% CI: 1.08 to 2.89), reporting high HIV testing self-efficacy (aORs = 13.5, 95% CIs: 6.0 to 30.1 and 9.81, 95% CI: 4.27 to 22.6) and having access to and use of non-HIV health-related services in the past 12 months (aORs = 13.2, 95% CIs: 6.85 to 25.6 and 7.15, 95% CI: 4.08 to 12.5) respectively. HIV testing coverage among YMSM aged 18 to 24 years old in Myanmar is still suboptimal. Integrated HIV testing and prevention services in existing health service

  8. Performance and reproducibility on shuttle run test between obese and non-obese children: a cross-sectional study.

    Science.gov (United States)

    Moran, Cristiane A; Peccin, Maria Stella; Bombig, Maria Teresa; Pereira, Silvana Alves; Dal Corso, Simone

    2017-03-09

    Due to the increasing prevalence of obesity among children, Shuttle Run Test (SRT) has been used as primary outcome for assessment of both physical performance and responses to different physical training programs. Thus, this study aimed to compare the performance on SRT between obese and non-obese children and the reproducibility of two SRTs carried out on different days. A cross-sectional study in which 40 children, aged from 8 to 10, were recruited from a public school. This study consisted of three visits in each school. On the first visit, we carried out a medical screening for recruited children. On the second visit, we applied the first SRT (SRT1), which was repeated on the third visit (SRT2, 24 hours apart). There was a significant difference in the distance traveled by non-obese in comparison with obese children (mean difference: 88 meters and 95% of confidence interval: 21 meters to 156 meters). Time and distance traveled of 27 children were higher in the SRT1, whereas nine children traveled a greater distance and presented higher testing time on the SRT2, with only four children showing the same distance traveled in both tests. Although both groups presented with reduction from the SRT1 to SRT2, this reduction was not significant (non-obese: 342 ± 97 meters to 319 ± 106 meters, respectively; obese: 269 ± 91 meters to 246 ± 90 meters, respectively). In obese children, the distance traveled in the best SRT had correlation with weight (r = -0.495, p = 0.043) and BMI (r = - 0.602, p = 0.011). No correlation was observed in the non-obese children. Overweight children had lower performance in SRT. Although reproducible, the best performance was in the first test, which leads us to suggest applying only one test.

  9. The precise measurements of integral (over spectrum of Cf-252) total neutron cross-sections and transmission coefficients for the testing of differential total cross-section

    Energy Technology Data Exchange (ETDEWEB)

    Guzhovskii, B.Ya.; Grebennikov, A.N.; Gorelov, V.P.; Farafontov, G.G.; Rudnev, V.S. [Russian Federal Nuclear Center, Arzamas (Russian Federation)

    1994-12-31

    The integral total cross-sections of nuclei Be, C, Al, Fe, Ni, Cu, Nb, Mo, Ta, W and U-238 were measured on Cf-252 spontaneous fission neutron spectrum and compared by calculated values from various libraries of evaluated neutron data.

  10. Child-Pugh Parameters and Platelet Count as an Alternative to ICG Test for Assessing Liver Function for Major Hepatectomy

    Directory of Open Access Journals (Sweden)

    Kin-Pan Au

    2017-01-01

    Full Text Available Objective. To study the correlations and discrepancies between Child-Pugh system and indocyanine green (ICG clearance test in assessing liver function reserve and explore the possibility of combining two systems to gain an overall liver function assessment. Design. Retrospective analysis of 2832 hepatocellular carcinoma (HCC patients graded as Child-Pugh A and Child-Pugh B with ICG clearance test being performed was conducted. Results. ICG retention rate at 15 minutes (ICG15 correlates with Child-Pugh score, however, with a large variance. Platelet count improves the correlation between Child-Pugh score and ICG15. ICG15 can be estimated using the following regression formula: estimated ICG15 (eICG15 = 45.1 + 0.435 × bilirubin − 0.917 × albumin + 0.491 × prothrombin time − 0.0283 × platelet (R2=0.455. Patients with eICG15 >20.0% who underwent major hepatectomy had a tendency towards more posthepatectomy liver failure (4.1% versus 8.0%, p=0.09 and higher in-hospital mortality (3.7% versus 8.0%, p=0.052. They also had shorter median overall survival (5.10±0.553 versus 3.01±0.878 years, p=0.015 and disease-free survival (1.37±0.215 versus 0.707±0.183 years, p=0.018. Conclusion. eICG15 can be predicted from Child-Pugh parameters and platelet count. eICG15 correlates with in-hospital mortality after major hepatectomy and predicts long-term survival.

  11. Assessment of various parameters using simple non-invasive tests in patients with cardiovascular diseases with or without cardiac rehabilitation

    Directory of Open Access Journals (Sweden)

    Takashi Ueda

    2016-09-01

    Full Text Available Cardiac rehabilitation (CR improves cardiac function and exercise capacity in patients with cardiovascular disease (CVD. Simpler techniques are needed for use by physicians in the examination room to assess the usefulness of CR. We enrolled 46 consecutive CVD patients in a CR program (CR group and prospectively followed them for 3 months. We compared them to 18 age-, gender- and body mass index-matched CVD patients without CR (non-CR group. Various parameters were measured at baseline and after 3 months using 3 simple non-invasive tests: severity of atherosclerosis [arterial velocity pulse index and arterial pressure volume index (API] were determined using PASESA®, an autonomic nerve total activity amount index and a coefficient of variation of the R–R interval (CVRR were determined using eHEART®, and peripheral resistance index, pressure rate product, stroke volume and cardiac index were determined using nico®]. There were no significant differences in patient characteristics including percentages (% of ischemic heart disease and heart failure between the non-CR and CR groups. Systolic blood pressure (SBP, diastolic BP, heart rate and API at baseline significantly decreased and CVRR at baseline significantly increased after 3 months in the CR group, but not in the non-CR group. In addition, ΔAPI (Δ = the value after 3 months minus the value at baseline was positively associated with ΔSBP in the CR group. In conclusion, CR significantly decreased BP and improved atherosclerosis and sympathetic nerve activity. These findings suggest that simple non-invasive tests may be useful for assessing the effects of CR.

  12. Usefulness of liver test and controlled attenuation parameter in detection of nonalcoholic fatty liver disease in patients with chronic renal failure and coronary heart disease.

    Science.gov (United States)

    Mikolasevic, Ivana; Orlic, Lidija; Zaputovic, Luka; Racki, Sanjin; Cubranic, Zlatko; Anic, Kata; Devcic, Bosiljka; Stimac, Davor

    2015-06-01

    In recent years, nonalcoholic fatty liver disease (NAFLD) was recognized as an important factor in chronic kidney disease (CKD) pathogenesis. The concentrations of serum aminotransferases in both chronic dialysis and chronic renal failure (CRF) patients most commonly fall within the lower end of the range of normal values. The aim of the present study was to investigate the usefulness of four liver tests and four biological scores in detection of NAFLD in comparison with transient elastography (TE) findings in different groups of patients. The study was cross-sectional analysis collected data from a single tertiary care center. Of 202 patents there were 52 patients with CKD, 50 patients with end-stage renal disease (ESRD) treated with haemodialysis (HD), 50 renal transplant recipients (RTRs) and 50 patients with proven coronary heart disease (CHD). Fifty sex- and age-matched individuals without NAFLD and with normal liver and kidney function tests served as controls. With the help of TE (FibroScan®, Echosense SA, Paris, France), liver stiffness was selected as the parameter to quantify liver fibrosis and Controlled Attenuation Parameter (CAP) was used to detect and quantify liver steatosis. According to the CAP findings 76.9 %CKD patients, 82 %HD patients, 74 %RTRs and 69.1 % CHD patients had CAP > 238 dB.m(-1) and thus by definition NAFLD. We have found that ALT, AST and GGT levels were positively correlated with CAP values while ALT and AST showed positive correlation with liver stiffness acquired with TE only in CHD patients. According to TE findings APRI (AUC 0.796) and FIB-4 (AUC 0.790) scores were correlated with the presence of fibrosis, while HIS score was correlated with the presence of steatosis (AUC 0.867) only in CHD patients. Liver tests and biological scores are not useful for NAFLD detection in CRF patients. TE with CAP provides the opportunity of noninvasive screening for NAFLD as well as liver fibrosis in patients with CRF.

  13. Resilient Modulus of Freeze-Thaw Affected Granular Soils for Pavement Design and Evaluation. Part 2. Field Validation Tests at Winchendon, Massachusetts, Test Sections,

    Science.gov (United States)

    1986-10-01

    tIloIII ( _ 0, P ll I I I P Ilil I I I I " ()31 0 󈨒 Wo 3 Ap 󈨓 -0 25Fb𔄃 - 9 a 9 ()72 Fer 󈨓 :0 79 Map 󈨓 1 2M t𔃺 o1 AtS (.) 12 Mar 󈨞 (0) IO Ap...analysis of the six test sections are sum- Radius (m) •0 0 2 04 0 6 08 1 0 o E 400 Actual Basin - -- j/ / Calculoated Baosin 00 .. ~~~~~ ~~1200 1 1...35 - Oacc’..c- 20.. -’. - I 055 35 a 12 March 1980 (Day 72) JAy." I 9eo D., Plate P .el 3rh(?.L) 237 PLato Pr cc,.c a:+ 2.S 155 l8q T(’C3 .. .’" d Ll

  14. Factors associated with continuing emergence of β-thalassemia major despite prenatal testing: a cross-sectional survey

    Directory of Open Access Journals (Sweden)

    Al Sabbah H

    2017-09-01

    Full Text Available Haleama Al Sabbah,1 Sarah Khan,1 Abdallah Hamadna,2 Lamia Abu Ghazaleh,2 Anwar Dudin,2 Bashar Adnan Karmi3 1College of Natural and Health Sciences, Zayed University, Dubai, UAE; 2Faculty of Medicine, An-Najah National University, Nablus, Palestine; 3Thalassemia Patients’ Friends Society, Ramallah, Palestine Purpose: Health care initiatives focusing on prenatal testing and premarital genetic screening aiming to reduce the incidence of β-thalassemia have emerged during the last decade. In Palestine, 4% of the population are known thalassemia carriers with new cases continuing to appear despite the availability of prenatal testing. This study aims to identify factors that influence the decision to retain or abort fetuses affected by β-thalassemia in Palestine. Methods: Convenience sampling was used to select 32 women (72 fetuses who were at risk of having a baby with β-thalassemia. A questionnaire on prenatal testing, test results, pregnancy outcomes, and factors influencing the decision to terminate the pregnancy were used for this cross-sectional study. The data were analyzed using SPSS version 17. Results: Among the fetuses screened, 36 (50% were thalassemia carriers and 20 (28% had β-thalassemia; 17 (85% affected fetuses were aborted. Religious beliefs were the most cited reason for opposing abortion while prior experience with β-thalassemia patients and awareness programs promoted abortions. Mothers who opted to retain an affected fetus had modest educational attainment. Higher educational level was significantly associated with the decision to abort an affected fetus (p<0.05. Conclusion: A religious consensus is needed on the abortion of fetuses affected by β-thalassemia. Improving female education and increasing awareness on thalassemia could help reduce the incidence of β-thalassemia in Palestine and around the world. Keywords: abortion, Islam, fetus, awareness

  15. Investigating the effect of tractive parameters on imposed vertical stresses under driving wheel using a soil bin test rig facility

    Directory of Open Access Journals (Sweden)

    H Taghavifar

    2015-09-01

    Full Text Available Introduction: Tire tractive parameters of the driving wheel are of the most substantial factors for the evaluation of the performance of agricultural tractors. Great tractive efficiency has called the attention of vehicle designers to attain economic efficiency owing to the minimization of fuel consumption. At terrain-tire interface, some soil physical-mechanical changes occur that lead to unwanted soil compaction. Of the influential parameters for the creation of soil compaction is the soil stresses formed owing to the wheeled vehicle trafficking. While the increase of tractive efficiency is desired, minimization of soil stresses should also be considered with the same importance to make a trade-off between the aforementioned parameters. There are numerous studies documented in the literature that deal with the measurement of soil stress/strain data due to the wheeled vehicle trafficking and also those works that address the correlation between the soil stress and soil compaction. It is recognized that in order to reduce soil compaction both at topsoil and subsoil levels, the soil stress at the soil-tire interface should be reduced. There are various parameters that affect the tractive efficiency and the soil stress creation such as wheel load, slip, tire inflation pressure, velocity, etc. On the other hand, the wheel is subjected to the torques and forces exerted to the vehicle and the vehicle dynamics are significantly affected by the soil-wheel interactions. Survey of the literature shows that numerous studies have focused on the evaluation of tractive efficiency both in field test and controlled conditions in laboratories with the intention of increasing tractive efficiency. The studies dedicated to the soil mechanical strength are more engaged with the approaches to minimize the soil stress propagation. The present study considers both factors and considers the most influential tire parameters such as wheel, velocity and slip to assess the

  16. Knowledge, attitude and practice towards voluntary counseling and testing among university students in North West Ethiopia: a cross sectional study

    Science.gov (United States)

    2013-01-01

    Background Voluntary counseling and testing (VCT) is one among different approaches which have been implemented as an attempt to slow the spread of HIV infection and minimize its impact at the individual, family and society level. VCT is perceived to be an effective strategy in risk reduction among sexually active young people like tertiary level students. Ethiopia as a country with high burden of HIV started responding to the epidemic by preparing and updating guidelines on VCT. The objective of this study was to assess the level of knowledge, attitude and practice of Voluntary Counseling and Testing (VCT) for HIV among university students in North West Ethiopia. Methods A cross sectional study was conducted from February to May 2010 using a stratified sampling method to enroll students from different faculties into the study. A total of 330 university students filled in a self-administered questionnaire with response rate of 97.3%. Main outcome measures included level of knowledge, attitude and practice of VCT for HIV. A chi-square test was used to determine an association between a number of independent factors and dependant variables. Result About 66.1% of the study participants were males with a mean age of 20 years. Majority (75.6%) of the respondents were Orthodox with 63% reported living in urban areas before joining the university. From the study participants 86.3% were knowledgeable on VCT, 73.3% had positive attitude towards VCT for HIV and 61.8% had had VCT for HIV in the past. Previous residence before joining the university, level of education, sex and religion were among the sociodemographic variables that showed statistically significant association with the one or more of the outcome variables. Fear of positive results, stigma and discrimination following the positive results were reported as main barriers for VCT uptake. Conclusion The findings reveal important barriers for VCT uptake and suggest strategies to reduce stigma and discrimination

  17. Knowledge, attitude and practice towards voluntary counseling and testing among university students in North West Ethiopia: a cross sectional study.

    Science.gov (United States)

    Addis, Zelalem; Yalew, Aregawi; Shiferaw, Yitayal; Alemu, Abebe; Birhan, Wubet; Mathewose, Biniam; Tachebele, Belayenesh

    2013-08-02

    Voluntary counseling and testing (VCT) is one among different approaches which have been implemented as an attempt to slow the spread of HIV infection and minimize its impact at the individual, family and society level. VCT is perceived to be an effective strategy in risk reduction among sexually active young people like tertiary level students. Ethiopia as a country with high burden of HIV started responding to the epidemic by preparing and updating guidelines on VCT. The objective of this study was to assess the level of knowledge, attitude and practice of Voluntary Counseling and Testing (VCT) for HIV among university students in North West Ethiopia. A cross sectional study was conducted from February to May 2010 using a stratified sampling method to enroll students from different faculties into the study. A total of 330 university students filled in a self-administered questionnaire with response rate of 97.3%. Main outcome measures included level of knowledge, attitude and practice of VCT for HIV. A chi-square test was used to determine an association between a number of independent factors and dependant variables. About 66.1% of the study participants were males with a mean age of 20 years. Majority (75.6%) of the respondents were Orthodox with 63% reported living in urban areas before joining the university. From the study participants 86.3% were knowledgeable on VCT, 73.3% had positive attitude towards VCT for HIV and 61.8% had had VCT for HIV in the past. Previous residence before joining the university, level of education, sex and religion were among the sociodemographic variables that showed statistically significant association with the one or more of the outcome variables. Fear of positive results, stigma and discrimination following the positive results were reported as main barriers for VCT uptake. The findings reveal important barriers for VCT uptake and suggest strategies to reduce stigma and discrimination.

  18. Walkability parameters, active transportation and objective physical activity: moderating and mediating effects of motor vehicle ownership in a cross-sectional study.

    Science.gov (United States)

    Eriksson, Ulf; Arvidsson, Daniel; Gebel, Klaus; Ohlsson, Henrik; Sundquist, Kristina

    2012-10-05

    Neighborhood walkability has been associated with physical activity in several studies. However, as environmental correlates of physical activity may be context specific, walkability parameters need to be investigated separately in various countries and contexts. Furthermore, the mechanisms by which walkability affects physical activity have been less investigated. Based on previous research, we hypothesized that vehicle ownership is a potential mediator. We investigated the associations between walkability parameters and physical activity, and the mediating and moderating effects of vehicle ownership on these associations in a large sample of Swedish adults. Residential density, street connectivity and land use mix were assessed within polygon-based network buffers (using Geographic Information Systems) for 2,178 men and women. Time spent in moderate to vigorous physical activity was assessed by accelerometers, and walking and cycling for transportation were assessed by the International Physical Activity Questionnaire. Associations were examined by linear regression and adjusted for socio-demographic characteristics. The product of coefficients approach was used to investigate the mediating effect of vehicle ownership. Residential density and land use mix, but not street connectivity, were significantly associated with time spent in moderate to vigorous physical activity and walking for transportation. Cycling for transportation was not associated with any of the walkability parameters. Vehicle ownership mediated a significant proportion of the association between the walkability parameters and physical activity outcomes. For residential density, vehicle ownership mediated 25% of the association with moderate to vigorous physical activity and 20% of the association with the amount of walking for transportation. For land use mix, the corresponding proportions were 34% and 14%. Vehicle ownership did not moderate any of the associations between the walkability

  19. Lumped-parameter models

    DEFF Research Database (Denmark)

    Ibsen, Lars Bo; Liingaard, Morten

    A lumped-parameter model represents the frequency dependent soil-structure interaction of a massless foundation placed on or embedded into an unbounded soil domain. The lumped-parameter model development have been reported by (Wolf 1991b; Wolf 1991a; Wolf and Paronesso 1991; Wolf and Paronesso 1992......; Wolf 1994; Wolf 1997; Wu and Lee 2002; Wu and Lee 2004). In this technical report the the steps of establishing a lumped-parameter model are presented. Following sections are included in this report: Static and dynamic formulation (Section 1.1), Simple lumped-parameter models (Section 1.2) and Advanced...... lumped-parameter models (Section 1.3)....

  20. Neutron Resonance Parameters of 238U and the Calculated Cross Sections from the Reich-Moore Analysis of Experimental Data in the Neutron Energy Range from 0 keV to 20 keV

    Energy Technology Data Exchange (ETDEWEB)

    Derrien, H

    2005-12-05

    The neutron resonance parameters of {sup 238}U were obtained from a SAMMY analysis of high-resolution neutron transmission measurements and high-resolution capture cross section measurements performed at the Oak Ridge Electron Linear Accelerator (ORELA) in the years 1970-1990, and from more recent transmission and capture cross section measurements performed at the Geel Linear Accelerator (GELINA). Compared with previous evaluations, the energy range for this resonance analysis was extended from 10 to 20 keV, taking advantage of the high resolution of the most recent ORELA transmission measurements. The experimental database and the method of analysis are described in this report. The neutron transmissions and the capture cross sections calculated with the resonance parameters are compared with the experimental data. A description is given of the statistical properties of the resonance parameters and of the recommended values of the average parameters. The new evaluation results in a slight decrease of the effective capture resonance integral and improves the prediction of integral thermal benchmarks by 70 pcm to 200 pcm.

  1. Community-based cross-sectional survey of latent tuberculosis infection in Afar pastoralists, Ethiopia, using QuantiFERON-TB Gold In-Tube and tuberculin skin test

    National Research Council Canada - National Science Library

    Legesse, Mengistu; Ameni, Gobena; Mamo, Gezahegne; Medhin, Girmay; Bjune, Gunnar; Abebe, Fekadu

    2011-01-01

    ...) and tuberculin skin tests (TST). A community-based cross-sectional survey of LTBI involving 652 apparently healthy adult pastoralists was undertaken in the pastoral community of Amibara District of the Afar Region between April and June 2010...

  2. On-Line Flutter Prediction Tool for Wind Tunnel Flutter Testing using Parameter Varying Estimation Methodology Project

    Data.gov (United States)

    National Aeronautics and Space Administration — ZONA Technology, Inc. (ZONA) proposes to develop an on-line flutter prediction tool for wind tunnel model using the parameter varying estimation (PVE) technique to...

  3. On-Line Flutter Prediction Tool for Wind Tunnel Flutter Testing using Parameter Varying Estimation Methodology Project

    Data.gov (United States)

    National Aeronautics and Space Administration — ZONA Technology, Inc. (ZONA) proposes to develop an on-line flutter prediction tool using the parameter varying estimation (PVE) methodology, called the PVE Toolbox,...

  4. Optimization of Weld Bead Parameters of Nickel Based Overlay Deposited by Plasma Transferred Arc Surfacing with Adequacy Test

    OpenAIRE

    Bhaskarananda Dasgupta; Pinaky Bhadury

    2014-01-01

    Plasma Transferred Arc surfacing is a kind of Plasma Transferred Arc Welding process. Plasma Transferred Arc surfacing (PTA) is increasingly used in applications where enhancement of wear, corrosion and heat resistance of materials surface is required. The shape of weld bead geometry affected by the PTA Welding process parameters is an indication of the quality of the weld. In this paper the analysis and optimization of weld bead parameters, during deposition of a Nickel based...

  5. Recommendations for the shallow-crack fracture toughness testing task within the HSST (Heavy-Section Steel Technology) Program

    Energy Technology Data Exchange (ETDEWEB)

    Theiss, T.J. (Oak Ridge National Lab., TN (USA))

    1990-09-01

    Recommendations for Heavy-Section Steel Technology Program's investigation into the influence of crack depth on the fracture toughness of a steel prototypic of those in a reactor pressure vessel are included in this report. The motivation for this investigation lies in the fact that probabilistic fracture mechanics evaluations show that shallow flaws play a dominant role in the likelihood of vessel failure, and shallow-flaw specimens have exhibited an elevated toughness compared with conventional deep-notch fracture toughness specimens. Accordingly, the actual margin of safety of vessels may be greater than that predicted using existing deep-notch fracture-toughness results. The primary goal of the shallow-crack project is to investigate the influence of crack depth on fracture toughness under conditions prototypic of a reactor vessel. A limited data base of fracture toughness values will be assembled using a beam specimen of prototypic reactor vessel material and with a depth of 100 mm (4 in.). This will permit comparison of fracture-toughness data from deep-cracked and shallow-crack specimens, and this will be done for several test temperatures. Fracture-toughness data will be expressed in terms of the stress-intensity factor and crack-tip-opening displacement. Results of this investigation are expected to improve the understanding of shallow-flaw behavior in pressure vessels, thereby providing more realistic information for application to the pressurized-thermal shock issues. 33 refs., 17 figs.

  6. Measurements of event properties and multi-differential jet cross sections and impact of CMS measurements on Proton Structure and QCD parameters

    CERN Document Server

    Kaur, Anterpreet

    2017-01-01

    We present results on the measurements of characteristics of events with jets including jet-charge, investigations of shapes and jet mass distributions. The measurements are compared to theoretical predictions including those matched to parton shower and hadronization. Multi-differential jet cross sections are also presented over a wide range in transverse momenta from inclusive jets to multi-jet final states. These measurements have an impact on the determination of the strong coupling constant as well as on parton distribution functions (PDFs) and are helpful in the treatment of heavy flavours in QCD analyses. We also show angular correlations in multi-jet events at highest center-of-mass energies and compare the measurements to theoretical predictions including higher order parton radiation and coherence effects. Measurements of cross sections of jet and top-quark pair production are in particular sensitive to the gluon distribution in the proton, while the electroweak boson production - inclusive or asso...

  7. Marine Hydrokinetic (MHK) Energy Conversion Research at UNH: From Fundamental Studies of Hydrofoil Sections, to Moderate Reynolds Number Turbine Tests in a Tow Tank, to Open Water Deployments at Tidal Energy Test Sites (Invited)

    Science.gov (United States)

    Wosnik, M.; Bachant, P.; Nedyalkov, I.; Rowell, M.; Dufresne, N.; Lyon, V.

    2013-12-01

    We report on research related to MHK turbines at the Center for Ocean Renewable Energy (CORE) at the University of New Hampshire (UNH). The research projects span varies scales, levels of complexity and environments - from fundamental studies of hydrofoil sections in a high speed water tunnel, to moderate Reynolds number turbine tests with inflow and wake studies in a large cross-section tow tank, to deployments of highly instrumented process models at tidal energy test sites in New England. A concerted effort over the past few years has brought significant new research infrastructure for marine hydrokinetic energy conversion online at UNH-CORE. It includes: a high-speed cavitation tunnel with independent control of velocity and pressure; a highly accurate tow mechanism, turbine test bed and wake traversing system for the 3.7m x 2.4m cross-section UNH tow tank; a 10.7m x 3.0m tidal energy test platform which can accommodate turbines up to 1.5m in diameter, for deployments at the UNH-CORE Tidal Energy Test Site in Great Bay Estuary, NH, a sheltered 'nursery site' suitable for intermediate scale tidal energy conversion device testing with peak currents typically above 2 m/s during each tidal cycle. Further, a large boundary layer wind tunnel, the new UNH Flow Physics Facility (W6.0m x H2.7m xL72m) is being used for detailed turbine wake studies, producing data and insight also applicable to MHK turbines in low Froude number deployments. Bi-directional hydrofoils, which perform equally well in either flow direction and could avoid the use of complex and maintenance-intensive yaw or blade pitch mechanisms, are being investigated theoretically, numerically and experimentally. For selected candidate shapes lift, drag, wake, and cavitation inception/desinence are measured. When combined with a cavitation inception model for MHK turbines, this information can be used to prescribe turbine design/operational parameters. Experiments were performed with a 1m diameter and 1m

  8. Comparison of options for reduction of noise in the test section of the NASA Langley 4x7m wind tunnel, including reduction of nozzle area

    Science.gov (United States)

    Hayden, R. E.

    1984-01-01

    The acoustically significant features of the NASA 4X7m wind tunnel and the Dutch-German DNW low speed tunnel are compared to illustrate the reasons for large differences in background noise in the open jet test sections of the two tunnels. Also introduced is the concept of reducing test section noise levels through fan and turning vane source reductions which can be brought about by reducing the nozzle cross sectional area, and thus the circuit mass flow for a particular exit velocity. The costs and benefits of treating sources, paths, and changing nozzle geometry are reviewed.

  9. Impact of heavy smoking on the clinical, microbiological and immunological parameters of patients with dental implants: a prospective cross-sectional study.

    Science.gov (United States)

    Ata-Ali, Javier; Flichy-Fernández, Antonio Juan; Alegre-Domingo, Teresa; Ata-Ali, Fadi; Peñarrocha-Diago, Miguel

    2016-11-01

    The aim of the present study was to investigate how heavy smoking influences the clinical, microbiological, and host-response characteristics in peri-implant sulcus fluid of patients with healthy dental implants. A total of 29 individuals with 74 dental implants were included in the present study; 20 implants were in heavy smokers and 54 were in non-smokers. The modified gingival index, modified plaque index, and probing pocket depth were evaluated. Periodontopathogenic bacteria Tannerella forsythia, Treponema denticola, and Porphyromonas gingivalis were evaluated, together with the total bacterial load. Peri-implant sulcus fluid samples were analyzed for the quantification of interleukin-8, interleukin-1β, interleukin-6, interleukin-10, and tumor necrosis factor-α. No significant differences in the clinical parameters evaluated were found between the groups, although smokers had poorer peri-implant parameters. Among the smokers, subgingival microbiota was composed of a greater number of periodontal pathogens; these differences were not statistically significant. Smokers showed a greater expression of interleukin-1β, interleukin-6, interleukin-10, and tumor necrosis factor-α, but interleukin-8 was slightly higher among non-smokers, but not significantly. Although smokers presented deeper probing depths, bleeding on probing, and peri-implant microbiota composed of a greater number of periodontal pathogens than in non-smoking patients, these data did not show significant differences. In the present study, and in relation to the samples analyzed, smoking alone did not influence the immunological and microbiological parameters in dental implants with healthy peri-implant tissues. Further studies with larger samples are required to better evaluate the influence of smoking on dental implants. © 2015 Wiley Publishing Asia Pty Ltd.

  10. Risk of mortality increases with increasing number of abnormal non-ST parameters recorded during exercise testing.

    Science.gov (United States)

    Ho, John S; Fitzgerald, Shannon J; Barlow, Carolyn E; Cannaday, John J; Kohl, Harold W; Haskell, William L; Cooper, Kenneth H

    2010-08-01

    Abnormal non-ST segment treadmill parameters are associated with an increased mortality risk. Such measures include fitness, resting heart rate (HR), chronotropic incompetence, and HR recovery. However, whether there is an additive association among these parameters and the risk of mortality is unknown. Prospective observational registry study. We assessed the risk of cardiovascular and all-cause mortality in 25 642 individuals as an additive function of the number of these parameters. Abnormal responses were defined as follows: abnormal resting HR as a HR>or=80 bpm, abnormal fitness as an adjusted fitness level in the lowest 20%, chronotropic incompetence as an inability to achieve at least 80% of the predicted HR reserve, and abnormal HR recovery as an HR decline less than 12 bpm 1 min after exercise. During 7.2 years of follow-up, 392 participants died, with 94 from cardiovascular causes. Each parameter was significantly associated with all-cause and cardiovascular mortality (Pmortality and the number of abnormal parameters (Ptesting.

  11. Large-scale aeroacoustic research feasibility and conceptual design of test-section inserts for the Ames 80- by 120-foot wind tunnel

    Science.gov (United States)

    Soderman, Paul T.; Olsen, Larry E.

    1990-01-01

    An engineering feasibility study was made of aeroacoustic inserts designed for large-scale acoustic research on aircraft models in the 80 by 120 foot Wind Tunnel at NASA Ames Research Center. The advantages and disadvantages of likely designs were analyzed. Results indicate that the required maximum airspeed leads to the design of a particular insert. Using goals of 200, 150, and 100 knots airspeed, the analysis indicated a 30 x 60 ft open-jet test section, a 40 x 80 ft open jet test section, and a 70 x 100 ft closed test section with enhanced wall lining, respectively. The open-jet inserts would be composed of a nozzle, collector, diffuser, and acoutic wedges incorporated in the existing 80 x 120 test section. The closed test section would be composed of approximately 5 ft acoustic wedges covered by a porous plate attached to the test section walls of the existing 80 x 120. All designs would require a double row of acoustic vanes between the test section and fan drive to attenuate fan noise and, in the case of the open-jet designs, to control flow separation at the diffuser downstream end. The inserts would allow virtually anechoic acoustic studies of large helicopter models, jets, and V/STOL aircraft models in simulated flight. Model scale studies would be necessary to optimize the aerodynamic and acoustic performance of any of the designs. In all designs studied, the existing structure would have to be reinforced. Successful development of acoustically transparent walls, though not strictly necessary to the project, would lead to a porous-wall test section that could be substituted for any of the open-jet designs, and thereby eliminate many aerodynamic and acoustic problems characteristic of open-jet shear layers. The larger size of the facility would make installation and removal of the insert components difficult. Consequently, scheduling of the existing 80 x 120 aerodynamic test section and scheduling of the open-jet test section would likely be made on an

  12. A STUDY OF THE DYNAMIC PARAMETERS INFLUENCE OVER THE BEHAVIOR OF THE TWO-SECTION ARTICULATED VEHICLE DURING THE LANE CHANGE MANOEUVRE

    Directory of Open Access Journals (Sweden)

    Rusi RUSEV

    2016-03-01

    Full Text Available The course stability and the steerability of the two-section wheeled vehicle at high velocities during the lane change manoeuvre are studied in this paper. Mechanic-mathematical model is developed, on which base simulation programmes are elaborated. Simulation studies of the course stability at different velocities depend on some constructive and exploitation factors are made by these models. Based on the simulation results an idea for an algorithm and a semi-active control system of the resistance in the pulling-supporting device is proposed.

  13. Estimation of Slow Crack Growth Parameters for Constant Stress-Rate Test Data of Advanced Ceramics and Glass by the Individual Data and Arithmetic Mean Methods

    Science.gov (United States)

    Choi, Sung R.; Salem, Jonathan A.; Holland, Frederic A.

    1997-01-01

    The two estimation methods, individual data and arithmetic mean methods, were used to determine the slow crack growth (SCG) parameters (n and D) of advanced ceramics and glass from a large number of room- and elevated-temperature constant stress-rate ('dynamic fatigue') test data. For ceramic materials with Weibull modulus greater than 10, the difference in the SCG parameters between the two estimation methods was negligible; whereas, for glass specimens exhibiting Weibull modulus of about 3, the difference was amplified, resulting in a maximum difference of 16 and 13 %, respectively, in n and D. Of the two SCG parameters, the parameter n was more sensitive to the estimation method than the other. The coefficient of variation in n was found to be somewhat greater in the individual data method than in the arithmetic mean method.

  14. Investigating the Effect of Sympathetic Skin Response Parameters on the Psychological Test Scores in Patients with Fibromyalgia Syndrome by Using ANNS

    Directory of Open Access Journals (Sweden)

    Murat Yıldız

    2013-01-01

    Full Text Available In this study, psychological tests such as Visual Analogue Pain Scale, Verbal Pain Scale, Beck Depression Inventory, Beck Anxiety Inventory, Hamilton Depression Rating Scale and Hamilton Anxiety Scale were applied to the selected healthy subjects and patients with Fibromyalgia Syndrome (FMS in Suleyman Demirel University, Faculty of Medicine, Department of Physical Medicine and Rehabilitation and the scores were recorded. A measurement system was established in the same department of the university to measure the sympathetic skin response (SSR from the subjects. The SSR was measured and recorded. The parameters such as latency time, maximum amplitude and the elapsed time were calculated by using Matlab software from the recorded SSR data. SSR parameters were added to the scores and diagnosis accuracy percentages of the FMS calculated by using artificial neural networks (ANNs. Obtained results from the simulations showed that the specified parameters of the SSR and FMS were concerned and these parameters can be used as a diagnostic method in FMS.

  15. The maximum Number of parameters for the Hausman Test When the Estimators are from Different Sets of Equations

    NARCIS (Netherlands)

    K. Nawata (Kazumitsu); M.J. McAleer (Michael)

    2013-01-01

    markdownabstract__Abstract__ Hausman (1978) developed a widely-used model specification test that has passed the test of time. The test is based on two estimators, one being consistent under the null hypothesis but inconsistent under the alternative, and the other being consistent under both the

  16. The Maximum Number of Parameters for the Hausman Test when the Estimators are from Different Sets of Equations

    NARCIS (Netherlands)

    K. Nawata (Kazumitsu); M.J. McAleer (Michael)

    2013-01-01

    markdownabstract__Abstract__ Hausman (1978) developed a widely-used model specification test that has passed the test of time. The test is based on two estimators, one being consistent under the null hypothesis but inconsistent under the alternative, and the other being consistent under both the

  17. 16 CFR Figure 3 to Part 1513 - Motion of Test Probe Arrested by Simultaneous Contact With Both Sides of “A” Section of Probe and...

    Science.gov (United States)

    2010-01-01

    ... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Motion of Test Probe Arrested by Simultaneous Contact With Both Sides of âAâ Section of Probe and Boundaries of Opening 3 Figure 3 to Part 1513... REQUIREMENTS FOR BUNK BEDS Pt. 1513, Fig. 3 Figure 3 to Part 1513—Motion of Test Probe Arrested by Simultaneous...

  18. Estimation of Genetic Parameters for First Lactation Monthly Test-day Milk Yields using Random Regression Test Day Model in Karan Fries Cattle

    Directory of Open Access Journals (Sweden)

    Ajay Singh

    2016-06-01

    Full Text Available A single trait linear mixed random regression test-day model was applied for the first time for analyzing the first lactation monthly test-day milk yield records in Karan Fries cattle. The test-day milk yield data was modeled using a random regression model (RRM considering different order of Legendre polynomial for the additive genetic effect (4th order and the permanent environmental effect (5th order. Data pertaining to 1,583 lactation records spread over a period of 30 years were recorded and analyzed in the study. The variance component, heritability and genetic correlations among test-day milk yields were estimated using RRM. RRM heritability estimates of test-day milk yield varied from 0.11 to 0.22 in different test-day records. The estimates of genetic correlations between different test-day milk yields ranged 0.01 (test-day 1 [TD-1] and TD-11 to 0.99 (TD-4 and TD-5. The magnitudes of genetic correlations between test-day milk yields decreased as the interval between test-days increased and adjacent test-day had higher correlations. Additive genetic and permanent environment variances were higher for test-day milk yields at both ends of lactation. The residual variance was observed to be lower than the permanent environment variance for all the test-day milk yields.

  19. Experimental Tests of Parameters Characterizing the Cooperation of Powered Roof Support Base and Floor of Low Bearing Capacity

    Science.gov (United States)

    Markowicz, Józef; Rajwa, Sylwester; Szweda, Stanisław

    2016-12-01

    Results of experimental tests aiming at determination of base pressure on the floor, carried out within "Geosoft" project, are presented. The tests included stand tests carried out with use of unique measuring instrumentation and special hydraulic cushion as well as tests of load of roof support set to load in operating longwall panel. The measurement results confirmed the necessity to consider the 3D model of cooperation of base and floor. Factors having impact on distribution of base pressure on the floor and its maximal value were identified, taking into account the test results.

  20. Nutritional parameters affecting severity of pneumonia and length of hospital stay in patients with pneumococcal pneumonia: a retrospective cross-sectional study.

    Science.gov (United States)

    Akuzawa, Nobuhiro; Naito, Hiroshi

    2015-11-25

    Pneumococcal pneumonia is the most common form of community-acquired pneumonia (CAP). Although a pneumococcal conjugate vaccine has contributed to a reduction in the incidence of pneumococcal pneumonia among older children and adults, no significant decrease in the incidence has been observed among persons aged ≥65 years. A low body mass index and hypoalbuminemia are common in Japanese patients with CAP, but the association of other nutritional parameters with the severity of pneumonia or length of hospital stay in patients with pneumococcal pneumonia is unclear. Fifty-seven previously healthy inpatients who presented with pneumococcal pneumonia were divided into two groups: those aged ≥65 years (n = 36) and those aged 65 years (CURB-65) score), the pneumonia severity index (PSI), and inflammatory and metabolic nutritional parameters were compared between the two groups. The older group showed significantly lower serum albumin and cholinesterase (ChE) levels. Multivariate linear regression analysis revealed that the PSI was positively correlated with age in both groups. In the younger age group, both the CURB-65 score and PSI showed significant negative correlations with the serum ChE level, and there was a significant negative correlation between the length of stay and serum total cholesterol (T-cho) level. In the older group, the fasting period, lymphocyte count, and age showed significant positive correlations with the length of stay. There was a significant negative correlation between the length of stay and serum albumin level, but no correlation with the serum ChE or T-cho levels, in the older patients. Our findings suggest that in patients aged pneumonia and length of stay. In contrast, the length of stay in older patients was associated with multiple factors that differed from those in younger patients. These differences may reflect age-related immunosenescence in older patients and a greater effect of serum ChE and T-cho levels on immunity in

  1. Quantitative reconstruction of cross-sectional dimensions and hydrological parameters of gravelly fluvial channels developed in a forearc basin setting under a temperate climatic condition, central Japan

    Science.gov (United States)

    Shibata, Kenichiro; Adhiperdana, Billy G.; Ito, Makoto

    2018-01-01

    Reconstructions of the dimensions and hydrological features of ancient fluvial channels, such as bankfull depth, bankfull width, and water discharges, have used empirical equations developed from compiled data-sets, mainly from modern meandering rivers, in various tectonic and climatic settings. However, the application of the proposed empirical equations to an ancient fluvial succession should be carefully examined with respect to the tectonic and climatic settings of the objective deposits. In this study, we developed empirical relationships among the mean bankfull channel depth, bankfull channel depth, drainage area, bankfull channel width, mean discharge, and bankfull discharge using data from 24 observation sites of modern gravelly rivers in the Kanto region, central Japan. Some of the equations among these parameters are different from those proposed by previous studies. The discrepancies are considered to reflect tectonic and climatic settings of the present river systems, which are characterized by relatively steeper valley slope, active supply of volcaniclastic sediments, and seasonal precipitation in the Kanto region. The empirical relationships derived from the present study can be applied to modern and ancient gravelly fluvial channels with multiple and alternate bars, developed in convergent margin settings under a temperate climatic condition. The developed empirical equations were applied to a transgressive gravelly fluvial succession of the Paleogene Iwaki Formation, Northeast Japan as a case study. Stratigraphic thicknesses of bar deposits were used for estimation of the bankfull channel depth. In addition, some other geomorphological and hydrological parameters were calculated using the empirical equations developed by the present study. The results indicate that the Iwaki Formation fluvial deposits were formed by a fluvial system that was represented by the dimensions and discharges of channels similar to those of the middle to lower reaches of

  2. The associations between atrial fibrillation and parameters of nutritional status assessment in the general hospital population - a cross-sectional analysis of medical documentation.

    Science.gov (United States)

    Budzyński, Jacek; Anaszewicz, Marzena

    2017-01-01

    Atrial fibrillation (AF) and nutrition status abnormalities are two of the most significant epidemics in current health care. The aim of this study was to determine the relationship between the prevalence and outcome of AF, and the parameters of nutritional status among consecutive, real-life patients hospitalised in a university hospital. Analysis of the medical documentation of 4930 consecutive patients aged ≥ 18 years hospitalised for more than one day with diagnoses of cardiovascular disorders. Patients admitted with a diagnosis of AF (n = 512) compared to their counterparts without AF less frequently had an NRS-2002 score ≥ 3, normal range of body mass index (BMI), higher blood haemoglobin, and lower low density lipoprotein cholesterol (LDL-C) concentration. In logistic regression analysis, the risk of a hospitalisation due to AF was negatively related to BMI, NRS-2002 score, and the value of the difference between ideal and actual body mass. Urgent admission and having an NRS-2002 score ≥ 3 remained the only significant variables determining the risk of in-hospital death. Blood concentration of LDL-C and urgent admission were the only significant variables determining risk of 30-day rehospitalisation in the studied population. Inpatients with AF had a lower prevalence of normal body mass. Patients with an AF diagnosis had different risk factors for in-hospital death and 30-day rehospitalisation than their counterparts with diagnosis of cardiovascular diseases but without AF; however, the parameters of nutritional status played an important role in both patient groups. The obesity and cholesterol paradoxes were also observed.

  3. Determination of parameters for the damage mechanics approach to ductile fracture based on a single fracture mechanics test

    NARCIS (Netherlands)

    Coppejans, O.J.; Walters, C.L.

    2017-01-01

    The local approach to modelling ductile tearing is a useful technique to give insight into fracture mechanics. However, applications of the local approach have been stymied by the high cost of finding the parameters that characterize it because of the number of specimens and expensive

  4. A computational framework for testing arrhythmia marker sensitivities to model parameters in functionally calibrated populations of atrial cells

    Science.gov (United States)

    Vagos, Márcia R.; Arevalo, Hermenegild; de Oliveira, Bernardo Lino; Sundnes, Joakim; Maleckar, Mary M.

    2017-09-01

    Models of cardiac cell electrophysiology are complex non-linear systems which can be used to gain insight into mechanisms of cardiac dynamics in both healthy and pathological conditions. However, the complexity of cardiac models can make mechanistic insight difficult. Moreover, these are typically fitted to averaged experimental data which do not incorporate the variability in observations. Recently, building populations of models to incorporate inter- and intra-subject variability in simulations has been combined with sensitivity analysis (SA) to uncover novel ionic mechanisms and potentially clarify arrhythmogenic behaviors. We used the Koivumäki human atrial cell model to create two populations, representing normal Sinus Rhythm (nSR) and chronic Atrial Fibrillation (cAF), by varying 22 key model parameters. In each population, 14 biomarkers related to the action potential and dynamic restitution were extracted. Populations were calibrated based on distributions of biomarkers to obtain reasonable physiological behavior, and subjected to SA to quantify correlations between model parameters and pro-arrhythmia markers. The two populations showed distinct behaviors under steady state and dynamic pacing. The nSR population revealed greater variability, and more unstable dynamic restitution, as compared to the cAF population, suggesting that simulated cAF remodeling rendered cells more stable to parameter variation and rate adaptation. SA revealed that the biomarkers depended mainly on five ionic currents, with noted differences in sensitivities to these between nSR and cAF. Also, parameters could be selected to produce a model variant with no alternans and unaltered action potential morphology, highlighting that unstable dynamical behavior may be driven by specific cell parameter settings. These results ultimately suggest that arrhythmia maintenance in cAF may not be due to instability in cell membrane excitability, but rather due to tissue-level effects which

  5. THE STATUS OF STUDENTS OF THE FACULTY OF PHYSICAL EDUCATION AND SPORTS IN COMPARISON WITH STANDARD PARAMETERS OF THE ILLINOIS AGILITY TEST

    Directory of Open Access Journals (Sweden)

    Malsor Gjonbalaj

    2015-05-01

    Full Text Available The aim of this study is to verify the current agility status of students of the Faculty of Physical Education and Sports of the University of Prishtina. Also, another aim was to compare results of the students with the international norms of the standard agility test. In this study were included 92 students of FPES. The agility tests were done based on the Illinois Agility Test as a standard test. The methods used to analyse the data obtained from the research, are standard methods, basic statistical parameters and comparative methods. From the basic statistical parameters, it was noticed a homogenous distribution of results. The distribution between the minimal and maximal result is from 15.15 – 20.16, with the average 16.54 and standard deviation 0.92. Based on the parameters on distribution, it is noticeable that the value of skew parameters is 1.43. Comparing to international norms of standard agility test, it is noticeable that the students if the Faculty of Physical Education and Sports have a satisfactory level and belong to the category of average results 16.54 sec, the international standard norms are 16.2 - 18.1 sec, which implies average achievement of results. Comparing to other groups of students, our sample showed almost the same results with the group of students tested by Mehmet Kutlu, Hakan Yapýcý, Oğuzhan Yoncalık, Serkan Çelik, 2012, where the results of their students are 16.54 ± 0.41, but the testing took place in synthetic carpet.

  6. Examining Testlet Effects in the TestDaF Listening Section: A Testlet Response Theory Modeling Approach

    Science.gov (United States)

    Eckes, Thomas

    2014-01-01

    Testlets are subsets of test items that are based on the same stimulus and are administered together. Tests that contain testlets are in widespread use in language testing, but they also share a fundamental problem: Items within a testlet are locally dependent with possibly adverse consequences for test score interpretation and use. Building on…

  7. Influence of the pesticides glyphosate, chlorpyrifos and atrazine on growth parameters of nonochratoxigenic Aspergillus section Nigri strains isolated from agricultural soils.

    Science.gov (United States)

    Carranza, Cecilia S; Barberis, Carla L; Chiacchiera, Stella M; Magnoli, Carina E

    2014-01-01

    This investigation was undertake to determine the effect of glyphosate, chlorpyrifos and atrazine on the lag phase and growth rate of nonochratoxigenic A. niger aggregate strains growing on soil extract medium at -0.70, -2.78 and -7.06 MPa. Under certain conditions, the glyphosate concentrations used significantly increased micelial growth as compared to control. An increase of about 30% was observed for strain AN 251 using 5 and 20 mg L(-1) of glyphosate at -2.78 MPa. The strains behaved differently in the presence of the insecticide chlorpyrifos. A significant decrease in growth rate, compared to control, was observed for all strains except AN 251 at -2.78 MPa with 5 mg L(-1). This strain showed a significant increase in growth rate. With regard to atrazine, significant differences were observed only under some conditions compared to control. An increase in growth rate was observed for strain AN 251 at -2.78 MPa with 5 and 10 mg L(-1) of atrazine. By comparison, a reduction of 25% in growth rate was observed at -7.06 MPa and higher atrazine concentrations. This study shows that glyphosate, chlorpyrifos and atrazine affect the growth parameters of nonochratoxigenic A. niger aggregate strains under in vitro conditions.

  8. Chemical Characterization and Kinetic parameter determination under Rancimat test conditions of four monovarietal virgin olive oils grown in Morocco

    Directory of Open Access Journals (Sweden)

    Gharby Said

    2016-07-01

    Full Text Available The aim of the present investigation is to compare the chemical characterization of four monovarietal virgin olive oils obtained from fruits of olive trees grown in Morocco (Picholine, Picual, Arebiquine, Koroneiki with kinetic parameters of oxidation based on Rancimat measurements and finally to assess the oxidative stabilities. The examined oils from different varieties showed a chemical composition within the regulatory limits. Rancimat measurements of induction times were carried out under isothermal conditions in an air atmosphere at temperatures from 373 to 423 K with intervals of 10 K. Using the Arrhenius-type correlation between the inverse induction times and the absolute temperature of the measurements, Ea, Z, and k values for oil oxidation under Rancimat conditions were calculated. The primary kinetic parameters derived from this method were qualitatively consistent and help to evaluate the oxidative stabilities of oils at increased temperatures.

  9. Using High-Resolution Data to Test Parameter Sensitivity of the Distributed Hydrological Model HydroGeoSphere

    Directory of Open Access Journals (Sweden)

    Thomas Cornelissen

    2016-05-01

    Full Text Available Parameterization of physically based and distributed hydrological models for mesoscale catchments remains challenging because the commonly available data base is insufficient for calibration. In this paper, we parameterize a mesoscale catchment for the distributed model HydroGeoSphere by transferring evapotranspiration parameters calibrated at a highly-equipped headwater catchment in addition to literature data. Based on this parameterization, the sensitivity of the mesoscale catchment to spatial variability in land use, potential evapotranspiration and precipitation and of the headwater catchment to mesoscale soil and land use data was conducted. Simulations of the mesoscale catchment with transferred parameters reproduced daily discharge dynamics and monthly evapotranspiration of grassland, deciduous and coniferous vegetation in a satisfactory manner. Precipitation was the most sensitive input data with respect to total runoff and peak flow rates, while simulated evapotranspiration components and patterns were most sensitive to spatially distributed land use parameterization. At the headwater catchment, coarse soil data resulted in a change in runoff generating processes based on the interplay between higher wetness prior to a rainfall event, enhanced groundwater level rise and accordingly, lower transpiration rates. Our results indicate that the direct transfer of parameters is a promising method to benefit highly equipped simulations of the headwater catchments.

  10. Parâmetros psicométricos: estudo comparativo entre testes de inteligência e de personalidade Psychometric parameters: comparative study between intelligence and personality tests

    Directory of Open Access Journals (Sweden)

    Ana Paula Porto Noronha

    2003-01-01

    Full Text Available A validade e a precisão de testes psicológicos vêm sendo bastante questionadas e discutidas atualmente. O presente estudo teve como objetivo avaliar a validade, a precisão e a existência de padronização brasileira em 43 testes psicológicos comercializados no Brasil, sendo 22 de inteligência e 21 de personalidade. Os testes foram comparados quanto ao período de publicação no Brasil. Os resultados indicaram que existe maior número de instrumentos publicados nas décadas de 1980 e 1990, que os testes de inteligência apresentam mais estudos de padronização, validade e precisão, embora não tenha havido diferença significante entre os grupos de testes (inteligência e personalidade. Novos estudos devem ser desenvolvidos com o intuito de promover os testes psicológicos e a área de avaliação psicológica, como um todo.Nowadays, the validity and the reliability of psychological tests are being very questioned and discussed. The current study aims to evaluate the validity, the reliability and the existence of Brazilian standardization in 43 psychological tests commercialized in Brazil, being 22 of intelligence and 21 of personality. The tests have been compared concearning the publication period in Brazil. The results have indicated that there is a bigger number of instruments published in the 1980´s and 1990´s, that the intelligence tests present more studies of standardization, validity and reliability, even though there hasn´t been significant difference among the groups tests (intelligence and personality. New studies must be developed aiming to promote the psychological tests and the area of psychological assessment, as a whole.

  11. Estimating the parameters of a structural model for the latent traits in Rasch's model for speed tests

    NARCIS (Netherlands)

    Jansen, MGH; Jansen, G.G.H.

    This article considers the multiplicative gamma model for reading speed originally proposed by Rasch (1960/1980) in his monograph Probabilistic Models for Some Intelligence and Attainment Tests. The model can be viewed as a latent trait model for a set of pure speed tests with known length,

  12. Towards Mobile Gait Analysis: Concurrent Validity and Test-Retest Reliability of an Inertial Measurement System for the Assessment of Spatio-Temporal Gait Parameters.

    Science.gov (United States)

    Kluge, Felix; Gaßner, Heiko; Hannink, Julius; Pasluosta, Cristian; Klucken, Jochen; Eskofier, Björn M

    2017-06-28

    The purpose of this study was to assess the concurrent validity and test-retest reliability of a sensor-based gait analysis system. Eleven healthy subjects and four Parkinson's disease (PD) patients were asked to complete gait tasks whilst wearing two inertial measurement units at their feet. The extracted spatio-temporal parameters of 1166 strides were compared to those extracted from a reference camera-based motion capture system concerning concurrent validity. Test-retest reliability was assessed for five healthy subjects at three different days in a two week period. The two systems were highly correlated for all gait parameters ( r > 0.93 ). The bias for stride time was 0 ± 16 ms and for stride length was 1.4 ± 6.7 cm. No systematic range dependent errors were observed and no significant changes existed between healthy subjects and PD patients. Test-retest reliability was excellent for all parameters (intraclass correlation (ICC) > 0.81) except for gait velocity (ICC > 0.55). The sensor-based system was able to accurately capture spatio-temporal gait parameters as compared to the reference camera-based system for normal and impaired gait. The system's high retest reliability renders the use in recurrent clinical measurements and in long-term applications feasible.

  13. Identification of material parameters using indentation test —study of the intrinsic dimensionality of P-h curves and residual imprints

    Directory of Open Access Journals (Sweden)

    Meng Liang

    2016-01-01

    Full Text Available Instrumented indentation test has been used to determine material parameters with two different sources of information. Based on the recent shape-manifold identification approach, we formally demonstrate, in the scope of manifold, the non-uniqueness of the solution to the inverse problem based on load-displacement curves. The identifiability is also compared for P-h curve and imprint mapping, highlighting the manifold’s ability to estimate the maximum number of independent material parameters that may be determined with a given experimental setup.

  14. High dairy protein intake is associated with greater bone strength parameters at the distal radius and tibia in older men: a cross-sectional study.

    Science.gov (United States)

    Langsetmo, L; Shikany, J M; Burghardt, A J; Cawthon, P M; Orwoll, E S; Cauley, J A; Taylor, B C; Schousboe, J T; Bauer, D C; Vo, T N; Ensrud, K E

    2017-10-23

    Dairy protein but not plant protein was associated with bone strength of the radius and tibia in older men. These results are consistent with previous results in women and support similar findings related to fracture outcomes. Bone strength differences were largely due to thickness and area of the bone cortex. Our objective was to determine the association of protein intake by source (dairy, non-dairy animal, plant) with bone strength and bone microarchitecture among older men. We used data from 1016 men (mean 84.3 years) who attended the Year 14 exam of the Osteoporotic Fractures in Men (MrOS) study, completed a food frequency questionnaire (500-5000 kcal/day), were not taking androgen or androgen agonists, and had high-resolution peripheral quantitative computed tomography (HR-pQCT) scans of the distal radius and distal or diaphyseal tibia. Protein was expressed as percentage of total energy intake (TEI); mean ± SD for TEI = 1548 ± 607 kcal/day and for total protein = 16.2 ± 2.9%TEI. We used linear regression with standardized HR-pQCT parameters as dependent variables and adjusted for age, limb length, center, education, race/ethnicity, marital status, smoking, alcohol intake, physical activity level, corticosteroids use, supplement use (calcium and vitamin D), and osteoporosis medications. Higher dairy protein intake was associated with higher estimated failure load at the distal radius and distal tibia [radius effect size = 0.17 (95% CI 0.07, 0.27), tibia effect size = 0.13 (95% CI 0.03, 0.23)], while higher non-dairy animal protein was associated with higher failure load at only the distal radius. Plant protein intake was not associated with failure load at any site. The association between protein intake and bone strength varied by source of protein. These results support a link between dairy protein intake and skeletal health, but an intervention study is needed to evaluate causality.

  15. Sensitivity Analysis of the Army Training and Testing Area Carrying Capacity (ATTACC) Model to User-specified Starting Parameters

    National Research Council Canada - National Science Library

    Anderson, Alan

    1999-01-01

    ...) program is a methodology for estimating training and testing land carrying capacity. The methodology is used to determine land rehabilitation and maintenance costs associated with land-based training and other uses...

  16. Testing iSpec for the determination of atmospheric parameters and abundances of δ Cephei and RR Lyrae

    Science.gov (United States)

    Blanco-Cuaresma, S.; Anderson, R. I.; Eyer, L.; Mowlavi, N.

    2017-03-01

    Classical Cepheids and RR Lyrae stars are radially pulsating stars where the spectral type varies according to pulsation phase. Several studies used synthesis and the equivalent width method to determine the variations of effective temperature, surface gravity and metallicity for classical Cepheids and RR Lyrae stars (Luck and Andrievsky 2004; Kovtyukh et al. 2005; Andrievsky et al 2005; Luck et al 2008; Takeda et al. 2013; Fossati et al. 2014). We evaluated the applicability of iSpec (Blanco-Cuaresma et al. 2014 - http://www.blancocuaresma.com/s/), which has been extensively used with non-pulsating FGK stars, and derived atmospheric parameters as a function of phase for δ Cephei and RR Lyrae (the two prototypes stars for each class). The results showed that when we apply a non-adapted traditional spectroscopic method to pulsating stars, derived gravities do not seem to follow a physically logical evolution. Nevertheless, metallicity is globally stable and effective temperature variations globally agree with expectations from the radius variations indicated by the radial velocity variability. Max/min values and average results agree with the literature. In terms of broadening parameters, macroturbulent and projected rotation velocities are very difficult to disentangle even if their profiles are not exactly the same. Individual chemical abundances as function of phase are stable as it was expected (the chemical composition of the star should not vary). We plan to use this information to identify absorption lines that are reliable and stable (less affected by blending) during the whole pulsating cycle. This new line selection may help to improve the determination of atmospheric parameters and it could allow us to be more confident in the study of other less known Cepheids and RR Lyrae stars.

  17. Kinetics Parameters of VVER-1000 Core with 3 MOX Lead Test Assemblies To Be Used for Accident Analysis Codes

    Energy Technology Data Exchange (ETDEWEB)

    Pavlovitchev, A.M.

    2000-03-08

    The present work is a part of Joint U.S./Russian Project with Weapons-Grade Plutonium Disposition in VVER Reactor and presents the neutronics calculations of kinetics parameters of VVER-1000 core with 3 introduced MOX LTAs. MOX LTA design has been studied in [1] for two options of MOX LTA: 100% plutonium and of ''island'' type. As a result, zoning i.e. fissile plutonium enrichments in different plutonium zones, has been defined. VVER-1000 core with 3 introduced MOX LTAs of chosen design has been calculated in [2]. In present work, the neutronics data for transient analysis codes (RELAP [3]) has been obtained using the codes chain of RRC ''Kurchatov Institute'' [5] that is to be used for exploitation neutronics calculations of VVER. Nowadays the 3D assembly-by-assembly code BIPR-7A and 2D pin-by-pin code PERMAK-A, both with the neutronics constants prepared by the cell code TVS-M, are the base elements of this chain. It should be reminded that in [6] TVS-M was used only for the constants calculations of MOX FAs. In current calculations the code TVS-M has been used both for UOX and MOX fuel constants. Besides, the volume of presented information has been increased and additional explications have been included. The results for the reference uranium core [4] are presented in Chapter 2. The results for the core with 3 MOX LTAs are presented in Chapter 3. The conservatism that is connected with neutronics parameters and that must be taken into account during transient analysis calculations, is discussed in Chapter 4. The conservative parameters values are considered to be used in 1-point core kinetics models of accident analysis codes.

  18. Hydrological Parameter Estimations from a Conservative Tracer Test With Variable-Density Effects at the Boise Hydrogeophysical Research Site

    Science.gov (United States)

    2011-12-15

    extrapolation of gained knowledge to other areas where only limited information may be available [e.g., Hyndman et al., 2000; Linde et al., 2006; Dafflon et al...long zones centered on the 4-m interval of the injection zone, although these wells were on the margin of the expected plume path. Similarly, samples...DAFFLON ET AL.: HYDROLOGICAL PARAMETER ESTIMATIONS W12513 4 of 19 a pumping rate was intended to (1) assure the plume pas- sage through A1, (2) ensure that

  19. Measurement of elastic pp scattering at √(s) = 8 TeV in the Coulomb-nuclear interference region: determination of the ρ-parameter and the total cross-section

    Energy Technology Data Exchange (ETDEWEB)

    Antchev, G.; Atanassov, I.; Broulim, P.; Eremin, V.; Georgiev, V.; Hammerbauer, J.; Linhart, R.; Oriunno, M.; Palocko, L.; Peroutka, Z. [University of West Bohemia, Pilsen (Czech Republic); Aspell, P.; Baechler, J.; Burkhardt, H.; Giani, S.; Karev, A.; Lucas Rodriguez, F.; Oliveri, E.; Palazzi, P.; Radermacher, E.; Ravotti, F.; Redaelli, S.; Ropelewski, L.; Ruggiero, G.; Salvachua, B.; Smajek, J.; Snoeys, W.; Valentino, G.; Wenninger, J. [CERN, Geneva (Switzerland); Avati, V. [AGH University of Science and Technology, Krakow (Poland); CERN, Geneva (Switzerland); Berardi, V.; Quinto, M. [INFN Sezione di Bari, Bari (Italy); Dipartimento Interateneo di Fisica di Bari, Bari (Italy); Berretti, M. [Universita degli Studi di Siena and Gruppo Collegato INFN di Siena, Siena (Italy); CERN, Geneva (Switzerland); Bossini, E.; Bottigli, U.; Latino, G.; Losurdo, L.; Turini, N. [Universita degli Studi di Siena and Gruppo Collegato INFN di Siena, Siena (Italy); Bozzo, M.; Lo Vetere, M. [INFN Sezione di Genova, Genoa (Italy); Universita degli Studi di Genova, Genoa (Italy); Buzzo, A.; Ferro, F.; Macri, M.; Minutoli, S.; Robutti, E. [INFN Sezione di Genova, Genoa (Italy); Cafagna, F.S.; Catanesi, M.G.; Fiergolski, A.; Mercadante, A.; Radicioni, E. [INFN Sezione di Bari, Bari (Italy); Campanella, C.E.; De Leonardis, F.; D' Orazio, A.; Guaragnella, C.; Passaro, V.; Petruzzelli, V.; Politi, T.; Prudenzano, F. [INFN Sezione di Bari, Bari (Italy); Dipartimento di Ingegneria Elettrica e dell' Informazione - Politecnico di Bari, Bari (Italy); Csanad, M.; Nemes, F.; Sziklai, J. [Wigner Research Centre for Physics, Budapest (Hungary); Csoergo, T. [Wigner Research Centre for Physics, Budapest (Hungary); KRF University College, Gyoengyoes (Hungary); Deile, M. [Dipartimento di Ingegneria Elettrica e dell' Informazione - Politecnico di Bari, Bari (Italy); Doubek, M.; Vacek, V. [Czech Technical University, Prague (Czech Republic); Eggert, K.; Niewiadomski, H.; Taylor, C. [Case Western Reserve University, Department of Physics, Cleveland, OH (United States); Garcia, F.; Heino, J.; Lauhakangas, R. [Helsinki Institute of Physics, Helsinki (Finland); Grzanka, L.; Wyszkowski, P.; Zielinski, K. [AGH University of Science and Technology, Krakow (Poland); Kaspar, J. [Institute of Physics of the Academy of Sciences of the Czech Republic, Prague (Czech Republic); CERN, Geneva (Switzerland); Kopal, J.; Kundrat, V.; Lokajicek, M.V.; Prochazka, J. [Institute of Physics of the Academy of Sciences of the Czech Republic, Prague (Czech Republic); Lami, S.; Scribano, A. [INFN Sezione di Pisa, Pisa (Italy); Lippmaa, E.; Lippmaa, J. [National Institute of Chemical Physics and Biophysics NICPB, Tallinn (Estonia); Minafra, N. [Dipartimento Interateneo di Fisica di Bari, Bari (Italy); CERN, Geneva (Switzerland); Naaranoja, T.; Oljemark, F.; Orava, R.; Oesterberg, K.; Saarikko, H.; Welti, J. [Helsinki Institute of Physics, Helsinki (Finland); University of Helsinki, Department of Physics, Helsinki (Finland)

    2016-12-15

    The TOTEM experiment at the CERN LHC has measured elastic proton-proton scattering at the centre-of-mass energy √(s) = 8 TeV and four-momentum transfers squared, vertical stroke t vertical stroke, from 6 x 10{sup -4} to 0.2 GeV{sup 2}. Near the lower end of the t-interval the differential cross-section is sensitive to the interference between the hadronic and the electromagnetic scattering amplitudes. This article presents the elastic cross-section measurement and the constraints it imposes on the functional forms of the modulus and phase of the hadronic elastic amplitude. The data exclude the traditional Simplified West and Yennie interference formula that requires a constant phase and a purely exponential modulus of the hadronic amplitude. For parametrisations of the hadronic modulus with second- or third-order polynomials in the exponent, the data are compatible with hadronic phase functions giving either central or peripheral behaviour in the impact parameter picture of elastic scattering. In both cases, the ρ-parameter is found to be 0.12 ± 0.03. The results for the total hadronic cross-section are σ{sub tot} = (102.9 ± 2.3) mb and (103.0 ± 2.3) mb for central and peripheral phase formulations, respectively. Both are consistent with previous TOTEM measurements. (orig.)

  20. Dynamic Testing of a Pre-stretched Flexible Tube for Identifying the Factors Affecting Modal Parameter Estimation

    Science.gov (United States)

    Unnikrishnan, Madhusudanan; Rajan, Akash; Basanthvihar Raghunathan, Binulal; Kochupillai, Jayaraj

    2017-08-01

    Experimental modal analysis is the primary tool for obtaining the fundamental dynamic characteristics like natural frequency, mode shape and modal damping ratio that determine the behaviour of any structure under dynamic loading conditions. This paper discusses about a carefully designed experimental method for calculating the dynamic characteristics of a pre-stretched horizontal flexible tube made of polyurethane material. The factors that affect the modal parameter estimation like the application time of shaker excitation, pause time between successive excitation cycles, averaging and windowing of measured signal, as well as the precautions to be taken during the experiment are explained in detail. The modal parameter estimation is done using MEscopeVESTM software. A finite element based pre-stressed modal analysis of the flexible tube is also done using ANSYS ver.14.0 software. The experimental and analytical results agreed well. The proposed experimental methodology may be extended for carrying out the modal analysis of many flexible structures like inflatables, tires and membranes.

  1. Development of functional lab-on-a-chip on polymer for point-of-care testing of metabolic parameters.

    Science.gov (United States)

    Do, Jaephil; Lee, Sehwan; Han, Jungyup; Kai, Junhai; Hong, Chien-Chong; Gao, Chuan; Nevin, Joseph H; Beaucage, Gregory; Ahn, Chong H

    2008-12-01

    This paper presents the development of an easy-to-handle and disposable clinical diagnostic lab-on-a-chip using fully integrated plastic microfluidic components, which has the sampling/identifying capability to make fast and reliable measurements of metabolic parameters from human whole blood. A smart and functional lab-on-a-chip cartridge, which incorporates a full on-chip auto-calibration function for in the field applications, has been developed, and then fully characterized using a portable analyzer (3 (1/4)''x 5''x 1'') with multi-analyte detection capability. In addition, several new approaches in realizing smart and functional lab-on-a-chips on polymer have been adopted, which include the pinch valve for automatic fluidic sealing, a by-pass channel as the sampling indicator, and a robust connector design for long analyzer lifetimes. Metabolic parameters such as glucose, lactate, and partial oxygen from human whole blood have been successfully measured using the functional polymer lab-on-a-chips and the portable analyzer developed in this work.

  2. DYNAMIC SOFTWARE TESTING MODELS WITH PROBABILISTIC PARAMETERS FOR FAULT DETECTION AND ERLANG DISTRIBUTION FOR FAULT RESOLUTION DURATION

    Directory of Open Access Journals (Sweden)

    A. D. Khomonenko

    2016-07-01

    Full Text Available Subject of Research.Software reliability and test planning models are studied taking into account the probabilistic nature of error detection and discovering. Modeling of software testing enables to plan the resources and final quality at early stages of project execution. Methods. Two dynamic models of processes (strategies are suggested for software testing, using error detection probability for each software module. The Erlang distribution is used for arbitrary distribution approximation of fault resolution duration. The exponential distribution is used for approximation of fault resolution discovering. For each strategy, modified labeled graphs are built, along with differential equation systems and their numerical solutions. The latter makes it possible to compute probabilistic characteristics of the test processes and states: probability states, distribution functions for fault detection and elimination, mathematical expectations of random variables, amount of detected or fixed errors. Evaluation of Results. Probabilistic characteristics for software development projects were calculated using suggested models. The strategies have been compared by their quality indexes. Required debugging time to achieve the specified quality goals was calculated. The calculation results are used for time and resources planning for new projects. Practical Relevance. The proposed models give the possibility to use the reliability estimates for each individual module. The Erlang approximation removes restrictions on the use of arbitrary time distribution for fault resolution duration. It improves the accuracy of software test process modeling and helps to take into account the viability (power of the tests. With the use of these models we can search for ways to improve software reliability by generating tests which detect errors with the highest probability.

  3. The Impact of Obesity and Insulin Resistance on Iron and Red Blood Cell Parameters: A Single Center, Cross-Sectional Study

    Directory of Open Access Journals (Sweden)

    Esma Altunoğlu

    2014-03-01

    Full Text Available OBJECTIVE: Obesity and iron deficiency (ID are the 2 most common nutritional disorders worldwide causing significant public health implications. Obesity is characterized by the presence of low-grade inflammation, which may lead to a number of diseases including insulin resistance (IR and type 2 diabetes. Increased levels of acute-phase proteins such as C-reactive protein (CRP have been reported in obesity-related inflammation. The aim of this study was to investigate the impact of obesity/IR on iron and red blood cell related parameters. METHODS: A total of 206 patients and 45 control subjects of normal weight were included in this crosssectional study. Venous blood samples were taken from each patient to measure hemoglobin (Hb, serum iron (Fe, ironbinding capacity (IBC, ferritin, CRP, fasting blood glucose, and fasting insulin. Body mass index (BMI and waist-to-hip ratio (WHR were calculated for each patient. IR was determined using the HOMA-IR formula. RESULTS: Subjects were divided into 3 groups according to BMI. There were 152 severely obese (BMI: 42.6±10.1, 54 mildly obese (BMI: 32.4±2.1, and 45 normal-weight (BMI: 24.3±1.3 patients. Hb levels in severely obese patients and normal controls were 12.8±1.3 g/dL and 13.6±1.8 g/dL, respectively. We found decreasing Fe levels with increasing weight (14.9±6.9 μmol/L, 13.6±6.3 μmol/L, and 10.9±4.6 μmol/L for normal controls and mildly and severely obese patients, respectively. Hb levels were slightly lower in patients with higher HOMA-IR values (13.1±1.5 g/dL vs. 13.2±1.2 g/dL; p=0.36. Serum iron levels were significantly higher in the group with low HOMA-IR values (13.6±5.9 μmol/L vs. 11.6±4.9 μmol/L; p=0.008. IBC was found to be similar in both groups (60.2±11.4 μmol/L vs. 61.9±10.7 μmol/L; p=0.23. Ferritin was slightly higher in patients with higher HOMA-IR values (156.1±209.5 pmol/L vs. 145.3±131.5 pmol/L; p=0.62. CONCLUSION: Elevated BMI and IR are associated with lower

  4. Correlation between the degree of air trapping in chest HRCT and cardiopulmonary exercise test parameters: could HRCT be a predictor of disease severity?

    Science.gov (United States)

    Ghanei, Mostafa; Sheyacy, Mohsen; Abbasi, Mohammad Amin; Ani, Alireza; Aslani, Jafar

    2011-03-01

    The purpose of this study was to examine whether the degree of air trapping in high resolution computed tomography (HRCT) of patients with histories of sulfur mustard gas exposure during suspended full expiration correlated with various parameters of the cardiopulmonary exercise test as the gold standard for assessment of pulmonary function. In this analytic study 75 male patients, each with a history of sulfur mustard gas exposure, were investigated. Each participant underwent an incremental cardiopulmonary exercise test, pulmonary function test and arterial oxygen saturation for hemoglobin measurement. For HRCT examination, both lungs were divided into three parts (upper, middle, and lower) and in each part images were separately observed from the involved area point of view (25% ≥6/24). A total of 49.3% of the patients (37/75) had evidence of air trapping in over 25% of their lung segments. The mean age±SD in the patients with air trapping of =25% or exercise test parameters. Also, no correlation was found between significant air trapping and exercise test findings in maximum exercise and anaerobic situations. No correlation was found between HRCT and cardiopulmonary exercise test findings. HRCT is neither pathognomic of the disease nor a good predictor of disease severity but it might be suggestive of mustard lung injuries.

  5. Standard model parameters determination and validity tests in Z{sup 0} hadronic disintegrations; Determination des parametres du modele standard et tests de sa validite dans les desintegrations hadroniques du Z{sup 0}

    Energy Technology Data Exchange (ETDEWEB)

    Todorov, T.

    1993-05-01

    This thesis describes the determination of the electroweak parameters from the measurements of the total hadronic cross-section by the DELPHI experiment at LEP-I. The analysed data was taken in the years 1991 and 1992; a previous analysis of the data taken in 1990 is included in the final fits. The first part of the thesis describes the interest of the measurement of the Z{sup 0} resonance parameters in the framework of the Standard Model as well as their implications for alternative models. The Standard Model predictions are described in some detail, and their precision is estimated. Then follows a brief description of the LEP collider, of the measurement of the collision energy, and of the experimental setup. A chapter is devoted to the description of the luminosity measurement, essential for the determination of total cross-sections. The measurement of the hadronic cross-section (event selection, study of backgrounds, study of sources of systematic uncertainties) is described in detail in the next chapter. Then follows a description of the method of the extraction of the resonance parameters, and a discussion of the uncertainties in their determination. The values obtained are interpreted in the framework of the Standard Model, as well as in the framework of some more general theories. Finally, the event generator for hadron production in two-photon collisions is described in the appendix. (author). 69 refs., 51 figs., 9 tabs., 1 ann.

  6. Single borehole test sensitivity towards crack and rock parameter. Lesson Hortberg; Einbohrlochtracertestsensitivitaet gegenueber Riss und Gesteinsparametern. Lektion Horstberg

    Energy Technology Data Exchange (ETDEWEB)

    Ghergut, Iulia; Behrens, Horst; Sauter, Martin [Goettingen Univ. (Germany). Angewandte Geologie

    2012-10-16

    The novel experiments of the GeoZentrum Hanover (Hanover, Federal Republic of Germany) on geothermal energy at the well bore Horstberg in the south heath also motivated the accompanying tracertest-mindset to move away from the tracer job stereotypes. For some possible designs at the tracertest at this drilling (forced-gradient divergent push by water fracking of Detfurth perforation, single-screen push-pull at Solling perforation, single-screen push-pull at Detfurth perforation, and so forth) the analysis shows how and why the controlling parameter do not comply with the mental basic pattern of the expectations at the tracertests ('tracertest by crack {yields} characterization of the crack', 'tracer residence time {yields} prognosis of the thermal lifetime').

  7. Development and vulnerability of rat brain and testes reflected by parameters for apoptosis and ornithine decarboxylase activity

    DEFF Research Database (Denmark)

    Lam, Henrik Rye; Dalgaard, Majken; Ladefoged, Ole

    2002-01-01

    apoptotic ladders were not detected between P9 and 60. In the testes, apoptotic laddering was weak from G21 to P15, but increased significantly from P15 to 60. Histologic examination and DNA laddering analyses revealed low-level germ cell apoptosis from G15 to P11. At onset of spermatogenesis at P15...

  8. The Effects of Test Content Match and Number of Items on the Accuracy of Trait Estimates from Tests Equated with the Three-Parameter Logistic Model.

    Science.gov (United States)

    Holmes, Susan E.

    The purpose of the present study was to examine the accuracy of indirect trait estimates, i.e., estimates of some primary trait obtained from a second measure which have been equated to the first. The California Achievement Test in Reading was the primary measure and the Prescriptive Reading Inventory was the indirect measure. Four kinds of…

  9. Involving women in personalised decision-making on mode of delivery after caesarean section: the development and pilot testing of a patient decision aid

    NARCIS (Netherlands)

    Schoorel, E.N.; Vankan, E.; Scheepers, H.C.J.; Augustijn, B.C.; Dirksen, C.D.; Koning, M.; Kuijk, S.M. van; Kwee, A.; Melman, S.; Nijhuis, J.G.; Aardenburg, R.; Boer, K. de; Hasaart, T.H.M.; Mol, B.W.; Nieuwenhuijze, M.; Pampus, M.G. van; Roosmalen, J. van; Roumen, F.J.M.E.; Vries, R. de; Wouters, M.G.A.J.; Weijden, T.T. van der; Hermens, R.P.M.G.

    2014-01-01

    OBJECTIVE: To develop a patient decision aid (PtDA) for mode of delivery after caesarean section that integrates personalised prediction of vaginal birth after caesarean (VBAC) with the elicitation of patient preferences and evidence-based information. DESIGN: A PtDA was developed and pilot tested

  10. Relationship between lung function and Modified Shuttle Test performance in adult patients with cystic fibrosis : A cross-sectional, retrospective study

    NARCIS (Netherlands)

    Doeleman, W. R.; Takken, T.; Bronsveld, I.; Hulzebos, E. H J

    2016-01-01

    Objectives: To investigate the relationship between lung function and exercise capacity in adults with cystic fibrosis (CF), and to develop a CF-specific equation to predict Modified Shuttle Test (MST) performance from baseline data. Design: Cross-sectional, retrospective study. Setting: Adult CF

  11. Triaging borderline/mild dyskaryotic Pap cytology with p16/Ki-67 dual-stained cytology testing: Cross-sectional and longitudinal outcome study

    NARCIS (Netherlands)

    M.H. Uijterwaal (Margot); B.I. Witte (Birgit); F.J. van Kemenade (Folkert); D.C. Rijkaart (Dorien); R. de Ridder (Rogier); J. Berkhof (Johannes); G.A.M.A. Balfoort-Van Der Meij (G. A M A); M.C.G. Bleeker; P.J.F. Snijders (Peter); C.J.L.M. Meijer (Chris J. L.)

    2014-01-01

    textabstractBackground: Women with borderline/mildly dyskaryotic (BMD) cytology smears are currently followed up with repeat testing at 6 and 18 months. The objective of this study is to analyse the cross-sectional and longitudinal performance of p16/Ki-67 dual-stained cytology for the detection of

  12. DYNAMIC CHANGES IN SPECTRAL HEART RATE VARIABILITY PARAMETERS IN PACED BREATHING TEST IN PATIENT WITH UNCONTROLLED ARTERIAL HYPERTENSION AND POLYMORBIDITY

    Directory of Open Access Journals (Sweden)

    L. Oyeleye

    2016-12-01

    Full Text Available A clinical case of a patient with uncontrolled hypertension and polymorbidity. The paced breathing test was made, was found prevalence of low frequency influences at the initial stage and its intensification at the resting stage, growth of the total power of heart rate variability spectrum (TP with respiratory modulation. The course of the disease worsened the appearance of new-onset atrial fibrillation (registered paroxysm on Holter monitoring; the general deterioration of the patient’s state reflected HRV changes on sinus rhythm tracing - significantly reduced TP growth in response to paced breathing, an increase in LF/HF (ratio of low frequency to high frequency waves, as well as switching to the neurohormonal level of heart rate regulation at the resting stage. After the treatment the growth of TP in response to the test has increased and LF/HF level has decreased.

  13. Baseline growth and reproductive parameters in Lymnaea stagnalis for OECD test guideline development: optimization of diets and culturing conditions

    DEFF Research Database (Denmark)

    Holbech, Henrik; Hutchinson, Tom

    guideline. Therefore, we have evaluated other diets based on a review of the published literature and report here the results for different feeds: namely, cabbage leaves, fish flakes, lettuce leaves or sliced sweet potato. For the feeding trial, 5 snails (shell size ca. 2.6 cm) were held in 1 L freshwater...... (sweet potato>cabbage leave diets (0.03 mm/snail/day). Similarly, in a 56-d ring-test study with 7 laboratories, the lettuce diet gave...

  14. Two-parameter fracture mechanical analysis of a near-crack-tip stress field in wedge splitting test specimens

    Czech Academy of Sciences Publication Activity Database

    Seitl, Stanislav; Veselý, V.; Řoutil, L.

    2011-01-01

    Roč. 89, 21-22 (2011), s. 1852-1858 ISSN 0045-7949. [International Conference on Civil, Structural and Enviromental Engineering Computing /12./. Funchal, Madeira, 01.09.2009-04.09.2009] Institutional research plan: CEZ:AV0Z20410507 Keywords : Wedge splitting test * Stress intensity factor * T-stress * Numerical simulation * Direct method Subject RIV: JL - Materials Fatigue, Friction Mechanics Impact factor: 1.874, year: 2011

  15. Risk, Benefit, and Cost Thresholds for Emergency Department Testing: A Cross-sectional, Scenario-based Study.

    Science.gov (United States)

    Meka, Arjun Prasad; Porath, Jonathan Douglas; Iyengar, Rahul; Morrow, Chelsea; Fagerlin, Angela; Meurer, William J

    2017-06-01

    While diagnostic testing is common in the emergency department, the value of some testing is questionable. The purpose of this study was to assess how varying levels of benefit, risk, and costs influenced an individual's desire to have diagnostic testing. A survey through Amazon Mechanical Turk presented hypothetical clinical situations: low-risk chest pain and minor traumatic brain injury. Each scenario included three given variables (benefit, risk, and cost), that was independently randomly varied over four possible values (0.1, 1, 5, and 10% for benefit and risk and $0, $100, $500, and $1,000 for the individual's personal cost for receiving the test). Benefit was defined as the probability of finding the target disease (traumatic intracranial hemorrhage or acute coronary syndrome). One-thousand unique respondents completed the survey. With an increased benefit from 0.1% to 10%, the percentage of respondents who accepted a diagnostic test went from 28.4% to 53.1%. (odds ratio [OR] = 3.42; 95% confidence interval [CI] = 2.57-4.54). As risk increased from 0.1% to 10%, this number decreased from 52.5% to 28.5%. (OR = 0.33; 95% CI = 0.25-0.44). Increasing cost from $0 to $1,000 had the greatest change of those accepting the test from 61.1% to 21.4%, respectively (OR = 0.15; 95% CI = 0.11-0.2). The desire for testing was strongly sensitive to the benefits, risks, and costs. Many participants wanted a test when there was no added cost, regardless of benefit or risk levels, but far fewer elected to receive the test as cost increased incrementally. This suggests that out-of-pocket costs may deter patients from undergoing diagnostic testing with low potential benefit. © 2016 by the Society for Academic Emergency Medicine.

  16. Testing of the Effect of Reaction Parameters on the Enzyme Immobilization by Adsorption and Cross-Linking Processes with Kinetic Desorption Method

    Directory of Open Access Journals (Sweden)

    Dániel Radva

    2011-01-01

    Full Text Available The activity of enzymes after the immobilization by weak interactions such as adsorption or adsorption followed by a cross-linking reaction can change easily not only during further application but during the activity measured via desorption and/or inactivation of enzymes. The changes in activity could be a consequence of the interactions between the enzyme and support. In this work a quick and efficient method is developed that permits studying of the strength and properties of the forces between the enzymes and support by examining the kinetics of desorption and/or inactivation. Applying this new cyclic kinetic desorption method, the effect of reaction parameters on immobilization could also be studied. The efficiency of this method was tested for optimizing the parameters for immobilization of β-glucosidase on Amberlite IRA 900 anion exchange resin by an adsorption followed by a cross-linking with glutaraldehyde to form potential preparation for food industry. The following parameters were chosen: concentration (0.10 M of the buffer (sodium acetate, pH=5.5 and the ratio of carrier to enzyme (10:1 for the adsorption step, then the time of treatment (1 min and concentration (0.25, by mass per volume of glutaraldehyde for the cross-linking by using the kinetic desorption method. The activity of this preparation was 57 μmol/(min·g in respect of dry resin. It was established that the effect of different parameters on this enzyme immobilization could be characterized by the new cyclic kinetic desorption method in a quick and efficient way; furthermore, it permitted separate testing of the effect of parameters on the adsorption and cross-linking processes.

  17. Associations between Both Lignan and Yogurt Consumption and Cardiovascular Risk Parameters in an Elderly Population: Observations from a Cross-Sectional Approach in the PREDIMED Study.

    Science.gov (United States)

    Creus-Cuadros, Anna; Tresserra-Rimbau, Anna; Quifer-Rada, Paola; Martínez-González, Miguel Angel; Corella, Dolores; Salas-Salvadó, Jordi; Fitó, Montse; Estruch, Ramon; Gómez-Gracia, Enrique; Lapetra, José; Arós, Fernando; Fiol, Miquel; Ros, Emili; Serra-Majem, Lluís; Pintó, Xavier; Moreno, Juan José; Ruiz-Canela, Miguel; Sorli, Jose Vicente; Basora, Josep; Schröder, Helmut; Lamuela-Raventós, Rosa Maria

    2017-04-01

    The study of dietary patterns is gaining interest. Although the health benefits of yogurt and lignans have been investigated separately, to our knowledge there are no studies on their associative effects. The aim of this study was to evaluate a possible association between yogurt and lignans using biomarkers of cardiovascular disease risk in an elderly population. We conducted a cross-sectional analysis of the association between baseline dietary information and cardiovascular risk parameters using food frequency questionnaires. We enrolled 7,169 Spanish participants of the PREDIMED (Prevención con Dieta Mediterránea) study (elderly men and women at high cardiovascular risk) from June 2003 to June 2009. Cardiovascular risk parameters, including cholesterol, triglycerides, glucose, body mass index, weight, waist circumference, and blood pressure were measured. General linear models were used to assess the relationship between categorical variables (yogurt, total dairy intake, lignans, and yogurt plus lignans) and cardiovascular risk parameters. The consumption of either yogurt or lignans seems to have beneficial effects on human health, but the consumption of both showed greater improvement in some cardiovascular health parameters. Indeed, participants with a higher consumption of both yogurt and lignans showed lower total cholesterol (estimated β-coefficients=-6.18; P=0.001) and low-density lipoprotein cholesterol levels (β=-4.92; P=0.005). In contrast, participants with lower yogurt and lignan consumption had a higher body mass index (β=0.28; P=0.007) and weight (β=1.20; P=0.008). High lignan and yogurt consumption is associated with a better cardiovascular risk parameters profile in an elderly Mediterranean population. Further research is warranted to determine the mechanisms and consequences of this potential effect. Copyright © 2017 Academy of Nutrition and Dietetics. Published by Elsevier Inc. All rights reserved.

  18. submitter Unified Scaling Law for flux pinning in practical superconductors: II. Parameter testing, scaling constants, and the Extrapolative Scaling Expression

    CERN Document Server

    Ekin, Jack W; Goodrich, Loren; Splett, Jolene; Bordini, Bernardo; Richter, David

    2016-01-01

    A scaling study of several thousand Nb3Sn critical-current $(I_c)$ measurements is used to derive the Extrapolative Scaling Expression (ESE), a relation that can quickly and accurately extrapolate limited datasets to obtain full three-dimensional dependences of I c on magnetic field (B), temperature (T), and mechanical strain (ε). The relation has the advantage of being easy to implement, and offers significant savings in sample characterization time and a useful tool for magnet design. Thorough data-based analysis of the general parameterization of the Unified Scaling Law (USL) shows the existence of three universal scaling constants for practical Nb3Sn conductors. The study also identifies the scaling parameters that are conductor specific and need to be fitted to each conductor. This investigation includes two new, rare, and very large I c(B,T,ε) datasets (each with nearly a thousand I c measurements spanning magnetic fields from 1 to 16 T, temperatures from ~2.26 to 14 K, and intrinsic strains from –...

  19. The effect of heat treatment and test parameters on the aqueous stress corrosion cracking of D6AC steel

    Science.gov (United States)

    Gilbreath, W. P.; Adamson, M. J.

    1974-01-01

    The crack growth behavior of D6AC steel as a function of stress intensity, stress and corrosion history and test technique, under sustained load in natural seawater, 3.3 percent NaCl solution, distilled water, and high humidity air was investigated. Reported investigations of D6AC were considered with emphasis on thermal treatment, specimen configuration, fracture toughness, crack-growth rates, initiation period, threshold, and the extension of corrosion fatigue data to sustained load conditions. Stress history effects were found to be most important in that they controlled incubation period, initial crack growth rates, and apparent threshold.

  20. Longitudinal Acceleration Test of Overhead Luggage Bins and Auxiliary Fuel Tank in a Transport Airplane Airframe Section, Part 2

    National Research Council Canada - National Science Library

    McGuire, Robert

    2000-01-01

    ...). The purpose of the tests was to measure the structural responses and interaction between the fuselage, overhead stowage bins, and auxiliary fuel tank under simulated, potentially survivable, crash conditions...

  1. Longitudinal Acceleration Tests of Overhead Luggage Bins and Auxiliary Fuel Tank in a Transport Airplane Airframe Section

    National Research Council Canada - National Science Library

    McGuire, Robert

    1999-01-01

    ...). The purpose of the tests was to measure the structural responses and interaction between the fuselage, overhead stowage bins, and auxiliary fuel tank under simulated, potentially survivable, crash conditions...

  2. Reference ranges for thromboelastography (TEG®) and traditional coagulation tests in term parturients undergoing caesarean section under spinal anaesthesia

    National Research Council Canada - National Science Library

    Macafee, B; Campbell, J. P; Ashpole, K; Cox, M; Matthey, F; Acton, L; Yentis, S. M

    2012-01-01

    There has been little published work defining ‘normal’ thromboelastography (TEG ® ) values in healthy parturients, and few large studies defining reference ranges for traditional coagulation tests in this patient group...

  3. Effect of operating parameters on the testing of new industrial titania catalysts at solar pilot plant scale

    Energy Technology Data Exchange (ETDEWEB)

    Malato, S.; Blanco, J.; Campos, A.; Caceres, J. [Plataforma Solar de Almeria-CIEMAT, Ctra. Senes Km. 4, Tabernas, 04200 Almeria (Spain); Guillard, C.; Herrmann, J.M. [Laboratoire d' Application de la Chimie a l' Environnement, LACE-CNRS-UMR5634, Universite Claude Bernard Lyon 1, 43 Blvd. du 11 Novembre 1918, 69622 Villeurbanne Cedex (France); Fernandez-Alba, A.R. [Pesticide Residue Research Group, University of Almeria, 04071 Almeria (Spain)

    2003-06-10

    A new granulated version of the well-known P-25 titanium dioxide (VP AEROPERL P-25/20 (Aeroperl)) has been tested to determine whether its photocatalytic efficiency is good enough for use in photocatalytic water purification and to find out if it can be separated from water more easily than its well-known homologue, powdered Degussa P-25, a significant technical improvement that might eliminate the tedious final filtration necessary with a slurry. Furthermore, a new commercial catalyst (PC-100 from Millennium Inorganic Chemicals), having a surface area and structure that are both different from Degussa P-25, has also been studied. All the experiments were carried out in sunlight in the pilot compound parabolic collector (CPC) plant at the Plataforma Solar de Almeria. Three different substrates were chosen as model molecules for this study: dichloracetic acid, phenol and the pesticide imidacloprid. Results show that Degussa Aeroperl is not a good alternative to powdered Degussa P-25 because of its spontaneous sedimentation during photocatalysis. Millennium PC-100 efficiency seems to be in the same range as that of Degussa P-25. In this work we also attempt to demonstrate that the comparison of efficiencies of different photocatalysts is not a trivial matter. Many factors are involved and interfere in the testing of photocatalyst behaviour during the degradation of a contaminant. A thorough comparison of photocatalyst activity should include reactions with several different substrates under varied experimental conditions.

  4. The effects of cutting parameters on cutting forces and heat generation when drilling animal bone and biomechanical test materials.

    Science.gov (United States)

    Cseke, Akos; Heinemann, Robert

    2018-01-01

    The research presented in this paper investigated the effects of spindle speed and feed rate on the resultant cutting forces (thrust force and torque) and temperatures while drilling SawBones ® biomechanical test materials and cadaveric cortical bone (bovine and porcine femur) specimens. It also investigated cortical bone anisotropy on the cutting forces, when drilling in axial and radial directions. The cutting forces are only affected by the feed rate, whereas the cutting temperature in contrast is affected by both spindle speed and feed rate. The temperature distribution indicates friction as the primary heat source, which is caused by the rubbing of the tool margins and the already cut chips over the borehole wall. Cutting forces were considerably higher when drilling animal cortical bone, in comparison to cortical test material. Drilling direction, and therewith anisotropy, appears to have a negligible effect on the cutting forces. The results suggest that this can be attributed to the osteons being cut at an angle rather than in purely axial or radial direction, as a result of a twist drill's point angle. Copyright © 2017 IPEM. Published by Elsevier Ltd. All rights reserved.

  5. Effects of time-of-day on oxidative stress, cardiovascular parameters, biochemical markers, and hormonal response following level-1 Yo-Yo intermittent recovery test.

    Science.gov (United States)

    Aloui, K; Abedelmalek, S; Chtourou, H; Wong, D P; Boussetta, N; Souissi, N

    2017-03-01

    The aim of this study was to investigate the effect of time-of-day on oxidative stress, cardiovascular parameters, muscle damage parameters, and hormonal responses following the level-1 Yo-Yo intermittent recovery test (YYIRT). A total of 11 healthy subjects performed an intermittent test (YYIRT) at two times-of-day (i.e., 07:00 h and 17:00 h), with a recovery period of ≥36 h in-between, in a randomized order. Blood samples were taken at the rest (baseline) and immediately (post-YYIRT) after the YYIRT for measuring oxidative stress, biochemical markers, and hormonal response. Data were statistically analyzed using one-way and two-way repeated measures ANOVA and Bonferroni test at p evening (17:00 h). There was also a main effect of time-of-day for cortisol and testosterone concentration, which were higher after the YYIRT in the morning (p evening. Low-density lipoprotein, systolic blood pressure, diastolic blood pressure, and lactate levels (p > 0.05) were similar for the morning and evening test. In conclusion, our findings suggest that aerobic performance presents diurnal variation with great result observed in the evening accompanied by an improvement of hormonal, metabolic, and oxidative responses. These data may help to guide athletes and coaches and contribute to public health recommendations on exercise and muscle damage particularly in the competitive periods.

  6. Experimental data on load test and performance parameters of a LENZ type vertical axis wind turbine in open environment condition

    Directory of Open Access Journals (Sweden)

    Seralathan Sivamani

    2017-12-01

    Full Text Available Performance and load testing data of a three bladed two stage LENZ type vertical axis wind turbine from the experiments conducted in an open environment condition at Hindustan Institute of Technology and Science, Chennai (location 23.2167°N, 72.6833°E are presented here. Low-wind velocity ranging from 2 to 11 m/s is available everywhere irrespective of climatic seasons and this data provides the support to the researchers using numerical tool to validate and develop an enhanced Lenz type design. Raw data obtained during the measurements are processed and presented in the form so as to compare with other typical outputs. The data is measured at different wind speeds prevalent in the open field condition ranging from 3 m/s to 9 m/s. Keywords: Vertical axis wind turbine, Lenz type, Performance, Two-stage, Open environment measurement

  7. Experimental data on load test and performance parameters of a LENZ type vertical axis wind turbine in open environment condition.

    Science.gov (United States)

    Sivamani, Seralathan; T, Micha Premkumar; Sohail, Mohammed; T, Mohan; V, Hariram

    2017-12-01

    Performance and load testing data of a three bladed two stage LENZ type vertical axis wind turbine from the experiments conducted in an open environment condition at Hindustan Institute of Technology and Science, Chennai (location 23.2167°N, 72.6833°E) are presented here. Low-wind velocity ranging from 2 to 11 m/s is available everywhere irrespective of climatic seasons and this data provides the support to the researchers using numerical tool to validate and develop an enhanced Lenz type design. Raw data obtained during the measurements are processed and presented in the form so as to compare with other typical outputs. The data is measured at different wind speeds prevalent in the open field condition ranging from 3 m/s to 9 m/s.

  8. Completion of therapeutic and safety monitoring tests in Lebanese outpatients on chronic medications: a cross-sectional study

    Directory of Open Access Journals (Sweden)

    Ramia E

    2014-09-01

    Full Text Available Elsy Ramia, Rony Zeenny Department of Pharmacy Practice, School of Pharmacy, Lebanese American University, Byblos, Lebanon Purpose: To evaluate the appropriateness of laboratory-test monitoring recommended for patients on chronic medication therapies in the Lebanese community setting.Patients and methods: In October 2011, all outpatients visiting selected community pharmacies in Lebanon were screened by pharmacists to evaluate their use of one or more chronic medications requiring safety and/or therapeutic laboratory tests. The list of medications was elaborated after an extensive review of laboratory-test monitoring recommendations from pertinent up-to-date clinical guidelines, medications that have been issued black box warnings for monitoring, and the most current information from the US Food and Drug Administration website. Patients receiving these medications were subjected to a questionnaire assessing the appropriateness of their laboratory-test monitoring. The study was approved by the Lebanese American University’s Institutional Review Board.Results: A total of 284 outpatients, with almost equal distribution by sex, were identified during the aforementioned period to be on one or more of the specified medications. The majority of the sample (68% was younger than 65 years of age. Overall, most of the study group (65% were found to be partially monitored with laboratory tests, while only 27% were fully monitored and 8% were not monitored at all. The study group reported clinic-visit intervals as follows: more than a year (35%, on yearly basis (18%, every 6 months (25%, every 3 months (16%, less than 3 months (6%. Conclusion: Seventy-three percent (73% of the study group were receiving incomplete therapeutic/safety laboratory-test monitoring recommended for patients on chronic medication in the Lebanese community. It is concluded from the results that patients need to better understand the importance of recommended test monitoring for the

  9. Access to diagnostic tests during GP out-of-hours care: A cross-sectional study of all GP out-of-hours services in the Netherlands.

    Science.gov (United States)

    Schols, Angel M R; Stevens, Femke; Zeijen, Camiel G I P; Dinant, Geert-Jan; van Vugt, Christel; Cals, Jochen W L

    2016-09-01

    In general practice, excluding serious conditions is one of the cornerstones of the consultation. Diagnostic tests are widely used to assist the decision-making process in these cases. Little is known about general practitioners' (GPs) access to diagnostic tests at GP out-of-hours services. To determine GPs' access to diagnostic tests-imaging, function tests, laboratory tests, and point-of-care tests (POCT)-during GP out-of-hours care and to assess whether access to diagnostic facilities differs between services located adjacent to or separate from an accident and emergency (A&E) department. Cross-sectional survey of all 117 GP out-of-hours services in the Netherlands in 2014. One-hundred-seventeen GP out-of-hours services participated in the survey; response rate 100%. Access to diagnostic tests during GP out-of-hours care varied across services, although generally there was limited access. Electrocardiography was available in 26% (30/117) of all services, conventional radiography in 19% (22/117), laboratory tests between 37% (43/117) and 65% (76/117). All services had glucose POCT and urine dipstick tests available while none utilized troponin POCT. We observed no relevant differences in access to diagnostic tests between services adjacent to or separate from an A&E department. GPs in the Netherlands had limited and varying access to diagnostic tests during GP out-of-hours care in 2014. Out-of-hours services adjacent to A&E departments do not offer wider access to diagnostic tests. Further research on the accessibility of diagnostic tests in other European countries with similar and different GP out-of-hours care systems could shed further light on the effects of accessibility to diagnostic tests. [Box: see text].

  10. Commissioning of the STAR test section for experimental simulation of loss of coolant accident using the EC-208 instrumented fuel assembly of the IEA-R1 reactor

    Energy Technology Data Exchange (ETDEWEB)

    Maprelian, Eduardo; Torres, Walmir M.; Prado, Adelk C.; Umbehaun, Pedro E.; Franca, Renato L.; Santos, Samuel C.; Macedo, Luiz A.; Sabundjian, Gaiane, E-mail: emaprel@ipen.br, E-mail: wmtorres@ipen.br, E-mail: acprado@ipen.br, E-mail: umbehaun@ipen.br, E-mail: rlfranca@ipen.br, E-mail: samuelcs@ipen.br, E-mail: lamacedo@ipen.br, E-mail: gdjian@ipen.br [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SO (Brazil)

    2015-07-01

    The three basic safety functions of Research Reactors (RR) are the safe shutdown of the reactor, the proper cooling of the decay heat of the fuel elements and the confinement of radioactive materials. Compared to Nuclear Power Reactors, RR power release is small, yet its three safety functions must be met to ensure the integrity of the reactor. During a loss of coolant accident (LOCA) in pool type RR, partial or complete loss of pool water may occur, with consequent partial or complete uncovering of the fuel assemblies. In such an accident, the decay heat removal safety function must not be compromised. The Test Section for Experimental Simulation of Loss of Coolant Accident (STAR) is in commissioning phase. This test section will provide experimental data on partial and total uncovering of the EC-208 instrumented fuel assembly (IFA) irradiated in the IEA-R1. Experimental results will be useful in validation of computer codes for RR safety analysis, particularly on heat removal efficiency aspects (safety function) in accident conditions. STAR comprises a base on which is installed the IFA, the cylindrical stainless steel hull, the compressed air system for the test section emptying and refilling, and the instrumentation for temperature and level measurements. The commissioning tests or pre-operational check, consist of several preliminary tests to verify experimental procedures, the difficulties during assembling of STAR in the pool, the difficulties in control the emptying and refilling velocities, as well as, the repeatability capacity, tests of equipment, valves and systems and tests of instrumentation and data acquisition system. Safety, accuracy and easiness of operation will be checked. (author)

  11. 78 FR 27860 - Revocation of TSCA Section 4 Testing Requirements for One High Production Volume Chemical Substance

    Science.gov (United States)

    2013-05-13

    ..., benzenesulfonic acid, [4-(phenylimino)-2,5- cyclohexadien-1-ylidene]methyl]phenyl]amino]- (CAS No. 1324-76-1... Blue 61 (Ref. 8). Likewise, a fish acute toxicity study and a chromosomal damage test of C.I. Pigment... for melting point, boiling point, vapor pressure, water solubility, biodegradation, fish acute...

  12. 77 FR 28340 - Revocation of TSCA Section 4 Testing Requirements for One High Production Volume Chemical Substance

    Science.gov (United States)

    2012-05-14

    ... Substances Control Act (TSCA) for benzenesulfonic acid, [4-(phenylimino)- 2,5-cyclohexadien-1-ylidene]methyl]phenyl]amino]- (CAS No. 1324-76-1), also known as C.I. Pigment Blue 61. EPA is basing its decision to...). Likewise, a fish acute toxicity study and a chromosomal damage test of C.I. Pigment Blue 56, which EPA...

  13. Factors Associated With Access to HIV Testing and Primary Care Among Migrants Living in Europe: Cross-Sectional Survey

    NARCIS (Netherlands)

    Fakoya, Ibidun; Álvarez-del Arco, Débora; Copas, Andrew J.; Teixeira, Bryan; Block, Koen; Gennotte, Anne-Francoise; Volny-Anne, Alain; Bil, Janneke P.; Touloumi, Giota; del Amo, Julia; Burns, Fiona M.

    2017-01-01

    There is a heavy and disproportionate burden of human immunodeficiency virus (HIV) infection among migrant communities living in Europe. Despite this, the published evidence related to HIV testing, prevention, and treatment needs for migrants is sparse. The aim of this study was to identify the

  14. Factors Associated With Access to HIV Testing and Primary Care Among Migrants Living in Europe: Cross-Sectional Survey.

    Science.gov (United States)

    Fakoya, Ibidun; Álvarez-Del Arco, Débora; Copas, Andrew J; Teixeira, Bryan; Block, Koen; Gennotte, Anne-Francoise; Volny-Anne, Alain; Bil, Janneke P; Touloumi, Giota; Del Amo, Julia; Burns, Fiona M

    2017-11-06

    There is a heavy and disproportionate burden of human immunodeficiency virus (HIV) infection among migrant communities living in Europe. Despite this, the published evidence related to HIV testing, prevention, and treatment needs for migrants is sparse. The aim of this study was to identify the factors associated with access to primary care and HIV testing among migrant groups living in Europe. A Web-based survey (available in 14 languages) was open to all people aged 18 years and older, living outside their country of birth in the World Health Organization (WHO) European area. Community organizations in 9 countries promoted the survey to migrant groups, focusing on those at a higher risk of HIV (sub-Saharan Africans, Latin Americans, gay or bisexual men, and people who inject drugs). Multivariable analysis examined factors associated with access to primary care and previous history of an HIV test. In total, 559 women, 395 heterosexual men, and 674 gay or bisexual men were included in the analysis, and 68.1% (359/527) of women, 59.5% (220/371) of heterosexual men, and 89.6% (596/664) of gay or bisexual men had tested for HIV. Low perceived risk was the reason given for not testing by 62.3% (43/69) of gay or bisexual men and 83.3% (140/168) of women and heterosexual men who reported never having tested for HIV. Access to primary care was >60% in all groups. Access to primary care was strongly positively associated with living in Northern Europe compared with Southern Europe (women: adjusted odds ratio, aOR 34.56 [95% CI 11.58-101]; heterosexual men: aOR 6.93 [95% CI 2.49-19.35], and gay or bisexual men: aOR 2.53 [95% CI 1.23-5.19]), whereas those with temporary residency permits were less likely to have access to primary care (women: aOR 0.41 [95% CI 0.21-0.80] and heterosexual men: aOR 0.24 [95% CI 0.10-0.54] only). Women who had experience of forced sex (aOR 3.53 [95% CI 1.39-9.00]) or postmigration antenatal care (aOR 3.07 [95% CI 1.55-6.07]) were more likely to

  15. Acute effects of Yo-Yo intermittent recovery test level 1 (Yo-YoIR1) on hemorheological parameters in female volleyball players.

    Science.gov (United States)

    Kilic-Toprak, Emine; Yapici, Ayşegül; Kilic-Erkek, Ozgen; Koklu, Yusuf; Tekin, Volkan; Alemdaroglu, Utku; Bor-Kucukatay, Melek

    2015-07-16

    In the present study, we investigated possible alterations in red blood cell (RBC) deformability, plasma and whole blood viscosities (WBV) and hematological parameters in response to Yo-Yo intermittent recovery test level 1 (Yo-YoIR1) which is currently used to assess endurance performance, in female volleyball players. Eight volleyball player volunteers from Pamukkale University (mean age19,9 ± 2,2 years; mean body height 177.5 ± 1.99 cm; mean body mass index 21.66 ± 0.64 kg/m2) participated to the study. Blood samples were collected before and immediately after test. Red blood cell (RBC) deformability was determined by ektacytometer, plasma and whole blood viscosities (WBV) by a cone-plate rotational viscometer. Hematological parameters were determined using an electronic hematology analyzer. The Yo-YoIR1 applied, induced acute increments in WBV at native hematocrit (Hct) measured at a shear rate of 150 s-1 and 375 s-1, RBC deformability and WBC count. The results of the current study indicate that, the Yo-Yo IR1 test used to determine physical capacity of the player, by resulting in increments in RBC deformability contributes blood flow and thus, athletic performance of the individual.

  16. Functional Balance and Motor Impairment Correlations with Gait Parameters during Timed Up and Go Test across Three Attentional Loading Conditions in Stroke Survivors

    Directory of Open Access Journals (Sweden)

    Haidzir Manaf

    2014-01-01

    Full Text Available The aim of this study was to determine whether stroke survivor’s gait performance during dual-task Timed Up and Go (TUG test is correlated with the level of functional balance and motor impairment. Thirty stroke survivors (22 men, 8 women were recruited for this study. The level of functional balance (Berg Balance Scale and motor impairment (Fugl-Meyer assessment lower extremity were assessed prior to the TUG test. TUG test was conducted under three attentional loading conditions (single, dual motor, and dual-cognitive. The time and number of steps were used to quantify gait parameters. The Spearmen’s rank correlation coefficient was used to evaluate the relationship between these variables. There was moderate to strong negative correlation between functional balance and gait parameters (range −0.53 to −0.73, P<0.05. There was a weak negative correlation observed between the time taken to complete the single task and motor impairment (rs=-0.43; P=0.02 dual motor task and motor impairment (rs=-0.41; P=0.02. However, there were no significant correlations between lower limb motor impairment and the number of steps in all conditions. These findings suggest that functional balance may be an influential domain of successful dual-task TUG in stroke.

  17. Critical power concept adapted for the specific table tennis test: comparisons between exhaustion criteria, mathematical modeling, and correlation with gas exchange parameters.

    Science.gov (United States)

    Zagatto, A; Miranda, M F; Gobatto, C A

    2011-07-01

    The purposes of this study were to determine and to compare the critical power concept adapted for the specific table tennis test (critical frequency - C F ) estimated from 5 mathematical models and using 2 different exhaustion criteria (voluntary and technical exhaustions). Also, it was an aim to assess the relationship between C F estimated from mathematical models and respiratory compensation point (RCP), peak oxygen uptake ( V˙O (2PEAK)) and minimal intensity at which V˙O (2PEAK) ( F V˙O (2PEAK)) appears. 9 male table tennis players [18(1) years; 62.3(4.4) kg] performed the maximal incremental test and 3-4 exhaustive exercise bouts to estimate C F s (balls · min (-1)). The exhaustion time and C F obtained were independent of the exhaustion criteria. The C F from 3-parameter model [45.2(7.0)-voluntary, 43.2(5.6)-technical] was lower than C F estimated by linear 2-parameter models, frequency-time (-1) [53.5(3.6)-voluntary, 53.5(3.5)-technical] and total ball thrown-time [52.2(3.5)-voluntary, 52.2(3.5)-technical] but significantly correlated. C F values from 2 linear models were significantly correlated with RCP [47.4(3.4) balls · min (-1)], and C F values of the linear and nonlinear models were correlated with F V˙O (2PEAK) [56.7(3.4) balls · min (-1)]. However, there were no significant correlations between C F values and V˙O (2PEAK) [49.8(1.1)ml · kg (-1) · min (-1)]. The results were not modified by exhaustion criteria. The 2 linear and non-linear 2-parameter models can be used to estimate aerobic endurance in specific table tennis tests. © Georg Thieme Verlag KG Stuttgart · New York.

  18. Investigating the Value of Section Scores for the "TOEFL iBT"® Test. "TOEFL iBT"® Research Report. TOEFL iBT-21. ETS Research Report RR-13-35

    Science.gov (United States)

    Sawaki, Yasuyo; Sinharay, Sandip

    2013-01-01

    This study investigates the value of reporting the reading, listening, speaking, and writing section scores for the "TOEFL iBT"® test, focusing on 4 related aspects of the psychometric quality of the TOEFL iBT section scores: reliability of the section scores, dimensionality of the test, presence of distinct score profiles, and the…

  19. The effect of air pollution on diurnal variation of performance in anaerobic tests, cardiovascular and hematological parameters, and blood gases on soccer players following the Yo-Yo Intermittent Recovery Test Level-1.

    Science.gov (United States)

    Boussetta, Nesrin; Abedelmalek, Salma; Aloui, Khouloud; Souissi, Nizar

    2017-01-01

    This study aimed to investigate the effect of air pollution on diurnal variation of performance in anaerobic tests, cardiovascular and hematological parameters, and blood gases on soccer players following the Yo-Yo Intermittent Recovery Test Level-1 (YYIRT1). In a randomized order, 11 healthy soccer players (mean age: 21.8 [range: 20-24] years; height: 178.00 [range: 1.64-1.83] cm; body mass index [BMI]: 23.57 [range: 20.45-28.03] kg.m-2) performed a YYIRT1 at two different times of day (TOD) (08:00 h and 18:00 h) in two areas (i.e. polluted (PA) and non-polluted (NPA)) with a recovery period of ≥ 72 h in between, to determine the maximal oxygen uptake (VO2max). In each test session: resting oral temperature is measured, anaerobic performances (pre- and post-YYIRT1) were performed, cardiovascular parameters and blood samples were collected at: rest, 3 min and 60 min after the YYIRT1, to assess blood gases and hematological parameters. Our results showed that, agility performance, VO2max, red blood cells (RBC), hemoglobin (Hb), pH, and bicarbonate levels (HCO3-) decrease significantly (p effect was slightly accentuated at 18:00 h for some parameters (i.e. Agility, HCO3-, HR, PvCO2, RBC, SBP). However, performances of sprint and Sargent jump test (SJT), oral temperature, rate of perceived exertion scales (RPE), partial pressure of O2 (PvO2), diastolic blood pressure (DBP), and monocytes (MON) were not affected by pollution (p > 0.05). In conclusion, pollution seems to be critical for health stability and performance in response to YYIRT1 especially in the evening and the winter season. Therefore, coaches and athletes should draw attention to the potential importance of land use planning in their training sessions and competitions in the morning in polluted area to minimize the risk of pollution exposure.

  20. The value of patch testing patients with a scattered generalized distribution of dermatitis: retrospective cross-sectional analyses of North American Contact Dermatitis Group data, 2001 to 2004.

    Science.gov (United States)

    Zug, Kathryn A; Rietschel, Robert L; Warshaw, Erin M; Belsito, Donald V; Taylor, James S; Maibach, Howard I; Mathias, C G Toby; Fowler, Joseph F; Marks, James G; DeLeo, Vincent A; Pratt, Melanie D; Sasseville, Denis; Storrs, Frances J

    2008-09-01

    A scattered generalized distribution (SGD) of dermatitis is a challenging problem; patch testing is a strategy for evaluating allergic contact dermatitis as a relevant factor. We sought to analyze patient characteristics and most frequently relevant positive allergens in patients presenting for patch testing with SGD. We conducted retrospective cross-sectional analysis of North American Contact Dermatitis Group 2001 to 2004 data. Patients with SGD were compared with patients without SGD. Of 10,061 patients, 14.9% (n = 1497) had only a SGD. Men and patients with a history of atopic eczema were more likely to have dermatitis in a SGD (P cosmetics/beauty preparations/skin and health care products, clothing, and topical corticoids. This was a retrospective analysis of patch-tested patients with SGD suspected to have allergy. A total of 49% of patients with SGD had at least one relevant positive allergen, thus demonstrating the benefit of patch testing these patients.

  1. Comparison of Parasitological, Serological, and Molecular Tests for Visceral Leishmaniasis in HIV-Infected Patients: A Cross-Sectional Delayed-Type Study

    Science.gov (United States)

    Cota, Gláucia Fernandes; de Sousa, Marcos Roberto; de Freitas Nogueira, Betânia Mara; Gomes, Luciana Inácia; Oliveira, Edward; Assis, Tália Santana Machado; de Mendonça, Andréa Laender Pessoa; Pinto, Bruna Fernandes; Saliba, Juliana Wilke; Rabello, Ana

    2013-01-01

    The aim of this study was to evaluate the accuracy of invasive and non-invasive tests for diagnosis of visceral leishmaniasis (VL) in a large series of human immunodeficiency virus (HIV)-infected patients. In this delayed-type cross-sectional study, 113 HIV-infected symptomatic patients were evaluated by an adjudication committee after clinical follow-up to establish the presence or absence of VL as the target condition (reference test). The index tests were recombinant K39 antigen-based immunochromatographic test (rK39), indirect fluorescent antibody test (IFAT), prototype kit of direct agglutination test (DAT-LPC), and real-time polymerase chain reaction (qPCR) in peripheral blood. Compared with parasitological test and adjudication committee diagnosis or latent class model analyses, IFAT and rk39 dipstick test presented the lowest sensitivity. DAT-LPC exhibited good overall performance, and there was no statistical difference between DAT-LPC and qPCR diagnosis accuracy. Real-time PCR emerges as a less invasive alternative to parasitological examination for confirmation of cases not identified by DAT. PMID:23836568

  2. Measurement of the ratio of inclusive jet cross sections using the anti-$k_T$ algorithm with radius parameters R=0.5 and 0.7 in pp collisions at $\\sqrt{s}$ = 7 TeV

    CERN Document Server

    Chatrchyan, Serguei; Sirunyan, Albert M; Tumasyan, Armen; Adam, Wolfgang; Bergauer, Thomas; Dragicevic, Marko; Erö, Janos; Fabjan, Christian; Friedl, Markus; Fruehwirth, Rudolf; Ghete, Vasile Mihai; Hartl, Christian; Hörmann, Natascha; Hrubec, Josef; Jeitler, Manfred; Kiesenhofer, Wolfgang; Knünz, Valentin; Krammer, Manfred; Krätschmer, Ilse; Liko, Dietrich; Mikulec, Ivan; Rabady, Dinyar; Rahbaran, Babak; Rohringer, Herbert; Schöfbeck, Robert; Strauss, Josef; Taurok, Anton; Treberer-Treberspurg, Wolfgang; Waltenberger, Wolfgang; Wulz, Claudia-Elisabeth; Mossolov, Vladimir; Shumeiko, Nikolai; Suarez Gonzalez, Juan; Alderweireldt, Sara; Bansal, Monika; Bansal, Sunil; Cornelis, Tom; De Wolf, Eddi A; Janssen, Xavier; Knutsson, Albert; Luyckx, Sten; Mucibello, Luca; Ochesanu, Silvia; Roland, Benoit; Rougny, Romain; Van Haevermaet, Hans; Van Mechelen, Pierre; Van Remortel, Nick; Van Spilbeeck, Alex; Blekman, Freya; Blyweert, Stijn; D'Hondt, Jorgen; Heracleous, Natalie; Kalogeropoulos, Alexis; Keaveney, James; Kim, Tae Jeong; Lowette, Steven; Maes, Michael; Olbrechts, Annik; Strom, Derek; Tavernier, Stefaan; Van Doninck, Walter; Van Mulders, Petra; Van Onsem, Gerrit Patrick; Villella, Ilaria; Caillol, Cécile; Clerbaux, Barbara; De Lentdecker, Gilles; Favart, Laurent; Gay, Arnaud; Léonard, Alexandre; Marage, Pierre Edouard; Mohammadi, Abdollah; Perniè, Luca; Reis, Thomas; Seva, Tomislav; Thomas, Laurent; Vander Velde, Catherine; Vanlaer, Pascal; Wang, Jian; Adler, Volker; Beernaert, Kelly; Benucci, Leonardo; Cimmino, Anna; Costantini, Silvia; Dildick, Sven; Garcia, Guillaume; Klein, Benjamin; Lellouch, Jérémie; Mccartin, Joseph; Ocampo Rios, Alberto Andres; Ryckbosch, Dirk; Salva Diblen, Sinem; Sigamani, Michael; Strobbe, Nadja; Thyssen, Filip; Tytgat, Michael; Walsh, Sinead; Yazgan, Efe; Zaganidis, Nicolas; Basegmez, Suzan; Beluffi, Camille; Bruno, Giacomo; Castello, Roberto; Caudron, Adrien; Ceard, Ludivine; Da Silveira, Gustavo Gil; Delaere, Christophe; Du Pree, Tristan; Favart, Denis; Forthomme, Laurent; Giammanco, Andrea; Hollar, Jonathan; Jez, Pavel; Komm, Matthias; Lemaitre, Vincent; Liao, Junhui; Militaru, Otilia; Nuttens, Claude; Pagano, Davide; Pin, Arnaud; Piotrzkowski, Krzysztof; Popov, Andrey; Quertenmont, Loic; Selvaggi, Michele; Vidal Marono, Miguel; Vizan Garcia, Jesus Manuel; Beliy, Nikita; Caebergs, Thierry; Daubie, Evelyne; Hammad, Gregory Habib; Alves, Gilvan; Correa Martins Junior, Marcos; Dos Reis Martins, Thiago; Pol, Maria Elena; Henrique Gomes E Souza, Moacyr; Aldá Júnior, Walter Luiz; Carvalho, Wagner; Chinellato, Jose; Custódio, Analu; Melo Da Costa, Eliza; De Jesus Damiao, Dilson; De Oliveira Martins, Carley; Fonseca De Souza, Sandro; Malbouisson, Helena; Malek, Magdalena; Matos Figueiredo, Diego; Mundim, Luiz; Nogima, Helio; Prado Da Silva, Wanda Lucia; Santaolalla, Javier; Santoro, Alberto; Sznajder, Andre; Tonelli Manganote, Edmilson José; Vilela Pereira, Antonio; Bernardes, Cesar Augusto; De Almeida Dias, Flavia; Tomei, Thiago; De Moraes Gregores, Eduardo; Lagana, Caio; Mercadante, Pedro G; Novaes, Sergio F; Padula, Sandra; Genchev, Vladimir; Iaydjiev, Plamen; Marinov, Andrey; Piperov, Stefan; Rodozov, Mircho; Sultanov, Georgi; Vutova, Mariana; Dimitrov, Anton; Glushkov, Ivan; Hadjiiska, Roumyana; Kozhuharov, Venelin; Litov, Leander; Pavlov, Borislav; Petkov, Peicho; Bian, Jian-Guo; Chen, Guo-Ming; Chen, He-Sheng; Chen, Mingshui; Du, Ran; Jiang, Chun-Hua; Liang, Dong; Liang, Song; Meng, Xiangwei; Plestina, Roko; Tao, Junquan; Wang, Xianyou; Wang, Zheng; Asawatangtrakuldee, Chayanit; Ban, Yong; Guo, Yifei; Li, Qiang; Li, Wenbo; Liu, Shuai; Mao, Yajun; Qian, Si-Jin; Wang, Dayong; Zhang, Linlin; Zou, Wei; Avila, Carlos; Carrillo Montoya, Camilo Andres; Chaparro Sierra, Luisa Fernanda; Florez, Carlos; Gomez, Juan Pablo; Gomez Moreno, Bernardo; Sanabria, Juan Carlos; Godinovic, Nikola; Lelas, Damir; Polic, Dunja; Puljak, Ivica; Antunovic, Zeljko; Kovac, Marko; Brigljevic, Vuko; Kadija, Kreso; Luetic, Jelena; Mekterovic, Darko; Morovic, Srecko; Sudic, Lucija; Attikis, Alexandros; Mavromanolakis, Georgios; Mousa, Jehad; Nicolaou, Charalambos; Ptochos, Fotios; Razis, Panos A; Finger, Miroslav; Finger Jr, Michael; Abdelalim, Ahmed Ali; Assran, Yasser; Elgammal, Sherif; Ellithi Kamel, Ali; Mahmoud, Mohammed; Radi, Amr; Kadastik, Mario; Müntel, Mait; Murumaa, Marion; Raidal, Martti; Rebane, Liis; Tiko, Andres; Eerola, Paula; Fedi, Giacomo; Voutilainen, Mikko; Härkönen, Jaakko; Karimäki, Veikko; Kinnunen, Ritva; Kortelainen, Matti J; Lampén, Tapio; Lassila-Perini, Kati; Lehti, Sami; Lindén, Tomas; Luukka, Panja-Riina; Mäenpää, Teppo; Peltola, Timo; Tuominen, Eija; Tuominiemi, Jorma; Tuovinen, Esa; Wendland, Lauri; Tuuva, Tuure; Besancon, Marc; Couderc, Fabrice; Dejardin, Marc; Denegri, Daniel; Fabbro, Bernard; Faure, Jean-Louis; Ferri, Federico; Ganjour, Serguei; Givernaud, Alain; Gras, Philippe; Hamel de Monchenault, Gautier; Jarry, Patrick; Locci, Elizabeth; Malcles, Julie; Nayak, Aruna; Rander, John; Rosowsky, André; Titov, Maksym; Baffioni, Stephanie; Beaudette, Florian; Busson, Philippe; Charlot, Claude; Daci, Nadir; Dahms, Torsten; Dalchenko, Mykhailo; Dobrzynski, Ludwik; Florent, Alice; Granier de Cassagnac, Raphael; Miné, Philippe; Mironov, Camelia; Naranjo, Ivo Nicolas; Nguyen, Matthew; Ochando, Christophe; Paganini, Pascal; Sabes, David; Salerno, Roberto; Sirois, Yves; Veelken, Christian; Yilmaz, Yetkin; Zabi, Alexandre; Agram, Jean-Laurent; Andrea, Jeremy; Bloch, Daniel; Brom, Jean-Marie; Chabert, Eric Christian; Collard, Caroline; Conte, Eric; Drouhin, Frédéric; Fontaine, Jean-Charles; Gelé, Denis; Goerlach, Ulrich; Goetzmann, Christophe; Juillot, Pierre; Le Bihan, Anne-Catherine; Van Hove, Pierre; Gadrat, Sébastien; Beauceron, Stephanie; Beaupere, Nicolas; Boudoul, Gaelle; Brochet, Sébastien; Chasserat, Julien; Chierici, Roberto; Contardo, Didier; Depasse, Pierre; El Mamouni, Houmani; Fan, Jiawei; Fay, Jean; Gascon, Susan; Gouzevitch, Maxime; Ille, Bernard; Kurca, Tibor; Lethuillier, Morgan; Mirabito, Laurent; Perries, Stephane; Ruiz Alvarez, José David; Sgandurra, Louis; Sordini, Viola; Vander Donckt, Muriel; Verdier, Patrice; Viret, Sébastien; Xiao, Hong; Tsamalaidze, Zviad; Autermann, Christian; Beranek, Sarah; Bontenackels, Michael; Calpas, Betty; Edelhoff, Matthias; Feld, Lutz; Hindrichs, Otto; Klein, Katja; Ostapchuk, Andrey; Perieanu, Adrian; Raupach, Frank; Sammet, Jan; Schael, Stefan; Sprenger, Daniel; Weber, Hendrik; Wittmer, Bruno; Zhukov, Valery; Ata, Metin; Caudron, Julien; Dietz-Laursonn, Erik; Duchardt, Deborah; Erdmann, Martin; Fischer, Robert; Güth, Andreas; Hebbeker, Thomas; Heidemann, Carsten; Hoepfner, Kerstin; Klingebiel, Dennis; Knutzen, Simon; Kreuzer, Peter; Merschmeyer, Markus; Meyer, Arnd; Olschewski, Mark; Padeken, Klaas; Papacz, Paul; Reithler, Hans; Schmitz, Stefan Antonius; Sonnenschein, Lars; Teyssier, Daniel; Thüer, Sebastian; Weber, Martin; Cherepanov, Vladimir; Erdogan, Yusuf; Flügge, Günter; Geenen, Heiko; Geisler, Matthias; Haj Ahmad, Wael; Hoehle, Felix; Kargoll, Bastian; Kress, Thomas; Kuessel, Yvonne; Lingemann, Joschka; Nowack, Andreas; Nugent, Ian Michael; Perchalla, Lars; Pooth, Oliver; Stahl, Achim; Asin, Ivan; Bartosik, Nazar; Behr, Joerg; Behrenhoff, Wolf; Behrens, Ulf; Bell, Alan James; Bergholz, Matthias; Bethani, Agni; Borras, Kerstin; Burgmeier, Armin; Cakir, Altan; Calligaris, Luigi; Campbell, Alan; Choudhury, Somnath; Costanza, Francesco; Diez Pardos, Carmen; Dooling, Samantha; Dorland, Tyler; Eckerlin, Guenter; Eckstein, Doris; Eichhorn, Thomas; Flucke, Gero; Geiser, Achim; Grebenyuk, Anastasia; Gunnellini, Paolo; Habib, Shiraz; Hauk, Johannes; Hellwig, Gregor; Hempel, Maria; Horton, Dean; Jung, Hannes; Kasemann, Matthias; Katsas, Panagiotis; Kieseler, Jan; Kleinwort, Claus; Krämer, Mira; Krücker, Dirk; Lange, Wolfgang; Leonard, Jessica; Lipka, Katerina; Lohmann, Wolfgang; Lutz, Benjamin; Mankel, Rainer; Marfin, Ihar; Melzer-Pellmann, Isabell-Alissandra; Meyer, Andreas Bernhard; Mnich, Joachim; Mussgiller, Andreas; Naumann-Emme, Sebastian; Novgorodova, Olga; Nowak, Friederike; Perrey, Hanno; Petrukhin, Alexey; Pitzl, Daniel; Placakyte, Ringaile; Raspereza, Alexei; Ribeiro Cipriano, Pedro M; Riedl, Caroline; Ron, Elias; Sahin, Mehmet Özgür; Salfeld-Nebgen, Jakob; Saxena, Pooja; Schmidt, Ringo; Schoerner-Sadenius, Thomas; Schröder, Matthias; Stein, Matthias; Vargas Trevino, Andrea Del Rocio; Walsh, Roberval; Wissing, Christoph; Aldaya Martin, Maria; Blobel, Volker; Enderle, Holger; Erfle, Joachim; Garutti, Erika; Goebel, Kristin; Görner, Martin; Gosselink, Martijn; Haller, Johannes; Höing, Rebekka Sophie; Kirschenmann, Henning; Klanner, Robert; Kogler, Roman; Lange, Jörn; Lapsien, Tobias; Lenz, Teresa; Marchesini, Ivan; Ott, Jochen; Peiffer, Thomas; Pietsch, Niklas; Rathjens, Denis; Sander, Christian; Schettler, Hannes; Schleper, Peter; Schlieckau, Eike; Schmidt, Alexander; Seidel, Markus; Poehlsen, Jennifer; Sola, Valentina; Stadie, Hartmut; Steinbrück, Georg; Troendle, Daniel; Usai, Emanuele; Vanelderen, Lukas; Barth, Christian; Baus, Colin; Berger, Joram; Böser, Christian; Butz, Erik; Chwalek, Thorsten; De Boer, Wim; Descroix, Alexis; Dierlamm, Alexander; Feindt, Michael; Guthoff, Moritz; Hartmann, Frank; Hauth, Thomas; Held, Hauke; Hoffmann, Karl-Heinz; Husemann, Ulrich; Katkov, Igor; Kornmayer, Andreas; Kuznetsova, Ekaterina; Lobelle Pardo, Patricia; Martschei, Daniel; Mozer, Matthias Ulrich; Müller, Thomas; Niegel, Martin; Nürnberg, Andreas; Oberst, Oliver; Quast, Gunter; Rabbertz, Klaus; Ratnikov, Fedor; Röcker, Steffen; Schilling, Frank-Peter; Schott, Gregory; Simonis, Hans-Jürgen; Stober, Fred-Markus Helmut; Ulrich, Ralf; Wagner-Kuhr, Jeannine; Wayand, Stefan; Weiler, Thomas; Wolf, Roger; Zeise, Manuel; Anagnostou, Georgios; Daskalakis, Georgios; Geralis, Theodoros; Kesisoglou, Stilianos; Kyriakis, Aristotelis; Loukas, Demetrios; Markou, Athanasios; Markou, Christos; Ntomari, Eleni; Psallidas, Andreas; Topsis-Giotis, Iasonas; Gouskos, Loukas; Panagiotou, Apostolos; Saoulidou, Niki; Stiliaris, Efstathios; Aslanoglou, Xenofon; Evangelou, Ioannis; Flouris, Giannis; Foudas, Costas; Jones, John; Kokkas, Panagiotis; Manthos, Nikolaos; Papadopoulos, Ioannis; Paradas, Evangelos; Bencze, Gyorgy; Hajdu, Csaba; Hidas, Pàl; Horvath, Dezso; Sikler, Ferenc; Veszpremi, Viktor; Vesztergombi, Gyorgy; Zsigmond, Anna Julia; Beni, Noemi; Czellar, Sandor; Molnar, Jozsef; Palinkas, Jozsef; Szillasi, Zoltan; Karancsi, János; Raics, Peter; Trocsanyi, Zoltan Laszlo; Ujvari, Balazs; Swain, Sanjay Kumar; Beri, Suman Bala; Bhatnagar, Vipin; Dhingra, Nitish; Gupta, Ruchi; Kaur, Manjit; Mehta, Manuk Zubin; Mittal, Monika; Nishu, Nishu; Sharma, Archana; Singh, Jasbir; Kumar, Ashok; Kumar, Arun; Ahuja, Sudha; Bhardwaj, Ashutosh; Choudhary, Brajesh C; Kumar, Ajay; Malhotra, Shivali; Naimuddin, Md; Ranjan, Kirti; Sharma, Varun; Shivpuri, Ram Krishen; Banerjee, Sunanda; Bhattacharya, Satyaki; Chatterjee, Kalyanmoy; Dutta, Suchandra; Gomber, Bhawna; Jain, Sandhya; Jain, Shilpi; Khurana, Raman; Modak, Atanu; Mukherjee, Swagata; Roy, Debarati; Sarkar, Subir; Sharan, Manoj; Singh, Anil; Abdulsalam, Abdulla; Dutta, Dipanwita; Kailas, Swaminathan; Kumar, Vineet; Mohanty, Ajit Kumar; Pant, Lalit Mohan; Shukla, Prashant; Topkar, Anita; Aziz, Tariq; Banerjee, Sudeshna; Chatterjee, Rajdeep Mohan; Dugad, Shashikant; Ganguly, Sanmay; Ghosh, Saranya; Guchait, Monoranjan; Gurtu, Atul; Kole, Gouranga; Kumar, Sanjeev; Maity, Manas; Majumder, Gobinda; Mazumdar, Kajari; Mohanty, Gagan Bihari; Parida, Bibhuti; Sudhakar, Katta; Wickramage, Nadeesha; Arfaei, Hessamaddin; Bakhshiansohi, Hamed; Behnamian, Hadi; Etesami, Seyed Mohsen; Fahim, Ali; Jafari, Abideh; Khakzad, Mohsen; Mohammadi Najafabadi, Mojtaba; Naseri, Mohsen; Paktinat Mehdiabadi, Saeid; Safarzadeh, Batool; Zeinali, Maryam; Grunewald, Martin; Abbrescia, Marcello; Barbone, Lucia; Calabria, Cesare; Chhibra, Simranjit Singh; Colaleo, Anna; Creanza, Donato; De Filippis, Nicola; De Palma, Mauro; Fiore, Luigi; Iaselli, Giuseppe; Maggi, Giorgio; Maggi, Marcello; Marangelli, Bartolomeo; My, Salvatore; Nuzzo, Salvatore; Pacifico, Nicola; Pompili, Alexis; Pugliese, Gabriella; Radogna, Raffaella; Selvaggi, Giovanna; Silvestris, Lucia; Singh, Gurpreet; Venditti, Rosamaria; Verwilligen, Piet; Zito, Giuseppe; Abbiendi, Giovanni; Benvenuti, Alberto; Bonacorsi, Daniele; Braibant-Giacomelli, Sylvie; Brigliadori, Luca; Campanini, Renato; Capiluppi, Paolo; Castro, Andrea; Cavallo, Francesca Romana; Codispoti, Giuseppe; Cuffiani, Marco; Dallavalle, Gaetano-Marco; Fabbri, Fabrizio; Fanfani, Alessandra; Fasanella, Daniele; Giacomelli, Paolo; Grandi, Claudio; Guiducci, Luigi; Marcellini, Stefano; Masetti, Gianni; Meneghelli, Marco; Montanari, Alessandro; Navarria, Francesco; Odorici, Fabrizio; Perrotta, Andrea; Primavera, Federica; Rossi, Antonio; Rovelli, Tiziano; Siroli, Gian Piero; Tosi, Nicolò; Travaglini, Riccardo; Albergo, Sebastiano; Cappello, Gigi; Chiorboli, Massimiliano; Costa, Salvatore; Giordano, Ferdinando; Potenza, Renato; Tricomi, Alessia; Tuve, Cristina; Barbagli, Giuseppe; Ciulli, Vitaliano; Civinini, Carlo; D'Alessandro, Raffaello; Focardi, Ettore; Gallo, Elisabetta; Gonzi, Sandro; Gori, Valentina; Lenzi, Piergiulio; Meschini, Marco; Paoletti, Simone; Sguazzoni, Giacomo; Tropiano, Antonio; Benussi, Luigi; Bianco, Stefano; Fabbri, Franco; Piccolo, Davide; Fabbricatore, Pasquale; Ferretti, Roberta; Ferro, Fabrizio; Lo Vetere, Maurizio; Musenich, Riccardo; Robutti, Enrico; Tosi, Silvano; Benaglia, Andrea; Dinardo, Mauro Emanuele; Fiorendi, Sara; Gennai, Simone; Gerosa, Raffaele; Ghezzi, Alessio; Govoni, Pietro; Lucchini, Marco Toliman; Malvezzi, Sandra; Manzoni, Riccardo Andrea; Martelli, Arabella; Marzocchi, Badder; Menasce, Dario; Moroni, Luigi; Paganoni, Marco; Pedrini, Daniele; Ragazzi, Stefano; Redaelli, Nicola; Tabarelli de Fatis, Tommaso; Buontempo, Salvatore; Cavallo, Nicola; Fabozzi, Francesco; Iorio, Alberto Orso Maria; Lista, Luca; Meola, Sabino; Merola, Mario; Paolucci, Pierluigi; Azzi, Patrizia; Bacchetta, Nicola; Bellato, Marco; Biasotto, Massimo; Bisello, Dario; Branca, Antonio; Checchia, Paolo; Dorigo, Tommaso; Dosselli, Umberto; Fanzago, Federica; Galanti, Mario; Gasparini, Fabrizio; Giubilato, Piero; Gozzelino, Andrea; Kanishchev, Konstantin; Lacaprara, Stefano; Lazzizzera, Ignazio; Margoni, Martino; Meneguzzo, Anna Teresa; Pazzini, Jacopo; Pozzobon, Nicola; Ronchese, Paolo; Simonetto, Franco; Torassa, Ezio; Tosi, Mia; Vanini, Sara; Zotto, Pierluigi; Zucchetta, Alberto; Zumerle, Gianni; Gabusi, Michele; Ratti, Sergio P; Riccardi, Cristina; Vitulo, Paolo; Biasini, Maurizio; Bilei, Gian Mario; Fanò, Livio; Lariccia, Paolo; Mantovani, Giancarlo; Menichelli, Mauro; Romeo, Francesco; Saha, Anirban; Santocchia, Attilio; Spiezia, Aniello; Androsov, Konstantin; Azzurri, Paolo; Bagliesi, Giuseppe; Bernardini, Jacopo; Boccali, Tommaso; Broccolo, Giuseppe; Castaldi, Rino; Ciocci, Maria Agnese; Dell'Orso, Roberto; Fiori, Francesco; Foà, Lorenzo; Giassi, Alessandro; Grippo, Maria Teresa; Kraan, Aafke; Ligabue, Franco; Lomtadze, Teimuraz; Martini, Luca; Messineo, Alberto; Moon, Chang-Seong; Palla, Fabrizio; Rizzi, Andrea; Savoy-Navarro, Aurore; Serban, Alin Titus; Spagnolo, Paolo; Squillacioti, Paola; Tenchini, Roberto; Tonelli, Guido; Venturi, Andrea; Verdini, Piero Giorgio; Vernieri, Caterina; Barone, Luciano; Cavallari, Francesca; Del Re, Daniele; Diemoz, Marcella; Grassi, Marco; Jorda, Clara; Longo, Egidio; Margaroli, Fabrizio; Meridiani, Paolo; Micheli, Francesco; Nourbakhsh, Shervin; Organtini, Giovanni; Paramatti, Riccardo; Rahatlou, Shahram; Rovelli, Chiara; Soffi, Livia; Traczyk, Piotr; Amapane, Nicola; Arcidiacono, Roberta; Argiro, Stefano; Arneodo, Michele; Bellan, Riccardo; Biino, Cristina; Cartiglia, Nicolo; Casasso, Stefano; Costa, Marco; Degano, Alessandro; Demaria, Natale; Mariotti, Chiara; Maselli, Silvia; Migliore, Ernesto; Monaco, Vincenzo; Musich, Marco; Obertino, Maria Margherita; Ortona, Giacomo; Pacher, Luca; Pastrone, Nadia; Pelliccioni, Mario; Potenza, Alberto; Romero, Alessandra; Ruspa, Marta; Sacchi, Roberto; Solano, Ada; Staiano, Amedeo; Tamponi, Umberto; Belforte, Stefano; Candelise, Vieri; Casarsa, Massimo; Cossutti, Fabio; Della Ricca, Giuseppe; Gobbo, Benigno; La Licata, Chiara; Marone, Matteo; Montanino, Damiana; Penzo, Aldo; Schizzi, Andrea; Umer, Tomo; Zanetti, Anna; Chang, Sunghyun; Kim, Tae Yeon; Nam, Soon-Kwon; Kim, Dong Hee; Kim, Gui Nyun; Kim, Ji Eun; Kim, Min Suk; Kong, Dae Jung; Lee, Sangeun; Oh, Young Do; Park, Hyangkyu; Son, Dong-Chul; Kim, Jae Yool; Kim, Zero Jaeho; Song, Sanghyeon; Choi, Suyong; Gyun, Dooyeon; Hong, Byung-Sik; Jo, Mihee; Kim, Hyunchul; Kim, Yongsun; Lee, Kyong Sei; Park, Sung Keun; Roh, Youn; Choi, Minkyoo; Kim, Ji Hyun; Park, Chawon; Park, Inkyu; Park, Sangnam; Ryu, Geonmo; Choi, Young-Il; Choi, Young Kyu; Goh, Junghwan; Kwon, Eunhyang; Lee, Byounghoon; Lee, Jongseok; Seo, Hyunkwan; Yu, Intae; Juodagalvis, Andrius; Komaragiri, Jyothsna Rani; Castilla-Valdez, Heriberto; De La Cruz-Burelo, Eduard; Heredia-de La Cruz, Ivan; Lopez-Fernandez, Ricardo; Martínez-Ortega, Jorge; Sánchez Hernández, Alberto; Villasenor-Cendejas, Luis Manuel; Carrillo Moreno, Salvador; Vazquez Valencia, Fabiola; Salazar Ibarguen, Humberto Antonio; Casimiro Linares, Edgar; Morelos Pineda, Antonio; Krofcheck, David; Butler, Philip H; Doesburg, Robert; Reucroft, Steve; Ahmad, Muhammad; Asghar, Muhammad Irfan; Butt, Jamila; Hoorani, Hafeez R; Khan, Wajid Ali; Khurshid, Taimoor; Qazi, Shamona; Shah, Mehar Ali; Shoaib, Muhammad; Bialkowska, Helena; Bluj, Michal; Boimska, Bożena; Frueboes, Tomasz; Górski, Maciej; Kazana, Malgorzata; Nawrocki, Krzysztof; Romanowska-Rybinska, Katarzyna; Szleper, Michal; Wrochna, Grzegorz; Zalewski, Piotr; Brona, Grzegorz; Bunkowski, Karol; Cwiok, Mikolaj; Dominik, Wojciech; Doroba, Krzysztof; Kalinowski, Artur; Konecki, Marcin; Krolikowski, Jan; Misiura, Maciej; Wolszczak, Weronika; Bargassa, Pedrame; Beirão Da Cruz E Silva, Cristóvão; Faccioli, Pietro; Ferreira Parracho, Pedro Guilherme; Gallinaro, Michele; Nguyen, Federico; Rodrigues Antunes, Joao; Seixas, Joao; Varela, Joao; Vischia, Pietro; Golutvin, Igor; Karjavin, Vladimir; Konoplyanikov, Viktor; Korenkov, Vladimir; Kozlov, Guennady; Lanev, Alexander; Malakhov, Alexander; Matveev, Viktor; Mitsyn, Valeri Valentinovitch; Moisenz, Petr; Palichik, Vladimir; Perelygin, Victor; Shmatov, Sergey; Shulha, Siarhei; Skatchkov, Nikolai; Smirnov, Vitaly; Tikhonenko, Elena; Zarubin, Anatoli; Golovtsov, Victor; Ivanov, Yury; Kim, Victor; Levchenko, Petr; Murzin, Victor; Oreshkin, Vadim; Smirnov, Igor; Sulimov, Valentin; Uvarov, Lev; Vavilov, Sergey; Vorobyev, Alexey; Vorobyev, Andrey; Andreev, Yuri; Dermenev, Alexander; Gninenko, Sergei; Golubev, Nikolai; Kirsanov, Mikhail; Krasnikov, Nikolai; Pashenkov, Anatoli; Tlisov, Danila; Toropin, Alexander; Epshteyn, Vladimir; Gavrilov, Vladimir; Lychkovskaya, Natalia; Popov, Vladimir; Safronov, Grigory; Semenov, Sergey; Spiridonov, Alexander; Stolin, Viatcheslav; Vlasov, Evgueni; Zhokin, Alexander; Andreev, Vladimir; Azarkin, Maksim; Dremin, Igor; Kirakosyan, Martin; Leonidov, Andrey; Mesyats, Gennady; Rusakov, Sergey V; Vinogradov, Alexey; Belyaev, Andrey; Boos, Edouard; Dubinin, Mikhail; Dudko, Lev; Ershov, Alexander; Gribushin, Andrey; Klyukhin, Vyacheslav; Kodolova, Olga; Lokhtin, Igor; Obraztsov, Stepan; Petrushanko, Sergey; Savrin, Viktor; Snigirev, Alexander; Azhgirey, Igor; Bayshev, Igor; Bitioukov, Sergei; Kachanov, Vassili; Kalinin, Alexey; Konstantinov, Dmitri; Krychkine, Victor; Petrov, Vladimir; Ryutin, Roman; Sobol, Andrei; Tourtchanovitch, Leonid; Troshin, Sergey; Tyurin, Nikolay; Uzunian, Andrey; Volkov, Alexey; Adzic, Petar; Dordevic, Milos; Ekmedzic, Marko; Milosevic, Jovan; Aguilar-Benitez, Manuel; Alcaraz Maestre, Juan; Battilana, Carlo; Calvo, Enrique; Cerrada, Marcos; Chamizo Llatas, Maria; Colino, Nicanor; De La Cruz, Begona; Delgado Peris, Antonio; Domínguez Vázquez, Daniel; Fernandez Bedoya, Cristina; Fernández Ramos, Juan Pablo; Ferrando, Antonio; Flix, Jose; Fouz, Maria Cruz; Garcia-Abia, Pablo; Gonzalez Lopez, Oscar; Goy Lopez, Silvia; Hernandez, Jose M; Josa, Maria Isabel; Merino, Gonzalo; Navarro De Martino, Eduardo; Puerta Pelayo, Jesus; Quintario Olmeda, Adrián; Redondo, Ignacio; Romero, Luciano; Senghi Soares, Mara; Willmott, Carlos; Albajar, Carmen; de Trocóniz, Jorge F; Missiroli, Marino; Brun, Hugues; Cuevas, Javier; Fernandez Menendez, Javier; Folgueras, Santiago; Gonzalez Caballero, Isidro; Lloret Iglesias, Lara; Brochero Cifuentes, Javier Andres; Cabrillo, Iban Jose; Calderon, Alicia; Chuang, Shan-Huei; Duarte Campderros, Jordi; Fernandez, Marcos; Gomez, Gervasio; Gonzalez Sanchez, Javier; Graziano, Alberto; Lopez Virto, Amparo; Marco, Jesus; Marco, Rafael; Martinez Rivero, Celso; Matorras, Francisco; Munoz Sanchez, Francisca Javiela; Piedra Gomez, Jonatan; Rodrigo, Teresa; Rodríguez-Marrero, Ana Yaiza; Ruiz-Jimeno, Alberto; Scodellaro, Luca; Vila, Ivan; Vilar Cortabitarte, Rocio; Abbaneo, Duccio; Auffray, Etiennette; Auzinger, Georg; Bachtis, Michail; Baillon, Paul; Ball, Austin; Barney, David; Bendavid, Joshua; Benhabib, Lamia; Benitez, Jose F; Bernet, Colin; Bianchi, Giovanni; Bloch, Philippe; Bocci, Andrea; Bonato, Alessio; Bondu, Olivier; Botta, Cristina; Breuker, Horst; Camporesi, Tiziano; Cerminara, Gianluca; Christiansen, Tim; Coarasa Perez, Jose Antonio; Colafranceschi, Stefano; D'Alfonso, Mariarosaria; D'Enterria, David; Dabrowski, Anne; David Tinoco Mendes, Andre; De Guio, Federico; De Roeck, Albert; De Visscher, Simon; Di Guida, Salvatore; Dobson, Marc; Dupont-Sagorin, Niels; Elliott-Peisert, Anna; Eugster, Jürg; Franzoni, Giovanni; Funk, Wolfgang; Giffels, Manuel; Gigi, Dominique; Gill, Karl; Giordano, Domenico; Girone, Maria; Giunta, Marina; Glege, Frank; Gomez-Reino Garrido, Robert; Gowdy, Stephen; Guida, Roberto; Hammer, Josef; Hansen, Magnus; Harris, Philip; Innocente, Vincenzo; Janot, Patrick; Karavakis, Edward; Kousouris, Konstantinos; Krajczar, Krisztian; Lecoq, Paul; Lourenco, Carlos; Magini, Nicolo; Malgeri, Luca; Mannelli, Marcello; Masetti, Lorenzo; Meijers, Frans; Mersi, Stefano; Meschi, Emilio; Moortgat, Filip; Mulders, Martijn; Musella, Pasquale; Orsini, Luciano; Palencia Cortezon, Enrique; Perez, Emmanuelle; Perrozzi, Luca; Petrilli, Achille; Petrucciani, Giovanni; Pfeiffer, Andreas; Pierini, Maurizio; Pimiä, Martti; Piparo, Danilo; Plagge, Michael; Racz, Attila; Reece, William; Rolandi, Gigi; Rovere, Marco; Sakulin, Hannes; Santanastasio, Francesco; Schäfer, Christoph; Schwick, Christoph; Sekmen, Sezen; Sharma, Archana; Siegrist, Patrice; Silva, Pedro; Simon, Michal; Sphicas, Paraskevas; Spiga, Daniele; Steggemann, Jan; Stieger, Benjamin; Stoye, Markus; Tsirou, Andromachi; Veres, Gabor Istvan; Vlimant, Jean-Roch; Wöhri, Hermine Katharina; Zeuner, Wolfram Dietrich; Bertl, Willi; Deiters, Konrad; Erdmann, Wolfram; Horisberger, Roland; Ingram, Quentin; Kaestli, Hans-Christian; König, Stefan; Kotlinski, Danek; Langenegger, Urs; Renker, Dieter; Rohe, Tilman; Bachmair, Felix; Bäni, Lukas; Bianchini, Lorenzo; Bortignon, Pierluigi; Buchmann, Marco-Andrea; Casal, Bruno; Chanon, Nicolas; Deisher, Amanda; Dissertori, Günther; Dittmar, Michael; Donegà, Mauro; Dünser, Marc; Eller, Philipp; Grab, Christoph; Hits, Dmitry; Lustermann, Werner; Mangano, Boris; Marini, Andrea Carlo; Martinez Ruiz del Arbol, Pablo; Meister, Daniel; Mohr, Niklas; Nägeli, Christoph; Nef, Pascal; Nessi-Tedaldi, Francesca; Pandolfi, Francesco; Pape, Luc; Pauss, Felicitas; Peruzzi, Marco; Quittnat, Milena; Ronga, Frederic Jean; Rossini, Marco; Starodumov, Andrei; Takahashi, Maiko; Tauscher, Ludwig; Theofilatos, Konstantinos; Treille, Daniel; Wallny, Rainer; Weber, Hannsjoerg Artur; Amsler, Claude; Chiochia, Vincenzo; De Cosa, Annapaola; Favaro, Carlotta; Hinzmann, Andreas; Hreus, Tomas; Ivova Rikova, Mirena; Kilminster, Benjamin; Millan Mejias, Barbara; Ngadiuba, Jennifer; Robmann, Peter; Snoek, Hella; Taroni, Silvia; Verzetti, Mauro; Yang, Yong; Cardaci, Marco; Chen, Kuan-Hsin; Ferro, Cristina; Kuo, Chia-Ming; Li, Syue-Wei; Lin, Willis; Lu, Yun-Ju; Volpe, Roberta; Yu, Shin-Shan; Bartalini, Paolo; Chang, Paoti; Chang, You-Hao; Chang, Yu-Wei; Chao, Yuan; Chen, Kai-Feng; Chen, Po-Hsun; Dietz, Charles; Grundler, Ulysses; Hou, George Wei-Shu; Hsiung, Yee; Kao, Kai-Yi; Lei, Yeong-Jyi; Liu, Yueh-Feng; Lu, Rong-Shyang; Majumder, Devdatta; Petrakou, Eleni; Shi, Xin; Shiu, Jing-Ge; Tzeng, Yeng-Ming; Wang, Minzu; Wilken, Rachel; Asavapibhop, Burin; Suwonjandee, Narumon; Adiguzel, Aytul; Bakirci, Mustafa Numan; Cerci, Salim; Dozen, Candan; Dumanoglu, Isa; Eskut, Eda; Girgis, Semiray; Gokbulut, Gul; Gurpinar, Emine; Hos, Ilknur; Kangal, Evrim Ersin; Kayis Topaksu, Aysel; Onengut, Gulsen; Ozdemir, Kadri; Ozturk, Sertac; Polatoz, Ayse; Sogut, Kenan; Sunar Cerci, Deniz; Tali, Bayram; Topakli, Huseyin; Vergili, Mehmet; Akin, Ilina Vasileva; Aliev, Takhmasib; Bilin, Bugra; Bilmis, Selcuk; Deniz, Muhammed; Gamsizkan, Halil; Guler, Ali Murat; Karapinar, Guler; Ocalan, Kadir; Ozpineci, Altug; Serin, Meltem; Sever, Ramazan; Surat, Ugur Emrah; Yalvac, Metin; Zeyrek, Mehmet; Gülmez, Erhan; Isildak, Bora; Kaya, Mithat; Kaya, Ozlem; Ozkorucuklu, Suat; Bahtiyar, Hüseyin; Barlas, Esra; Cankocak, Kerem; Günaydin, Yusuf Oguzhan; Vardarli, Fuat Ilkehan; Yücel, Mete; Levchuk, Leonid; Sorokin, Pavel; Brooke, James John; Clement, Emyr; Cussans, David; Flacher, Henning; Frazier, Robert; Goldstein, Joel; Grimes, Mark; Heath, Greg P; Heath, Helen F; Jacob, Jeson; Kreczko, Lukasz; Lucas, Chris; Meng, Zhaoxia; Newbold, Dave M; Paramesvaran, Sudarshan; Poll, Anthony; Senkin, Sergey; Smith, Vincent J; Williams, Thomas; Bell, Ken W; Belyaev, Alexander; Brew, Christopher; Brown, Robert M; Cockerill, David JA; Coughlan, John A; Harder, Kristian; Harper, Sam; Ilic, Jelena; Olaiya, Emmanuel; Petyt, David; Shepherd-Themistocleous, Claire; Thea, Alessandro; Tomalin, Ian R; Womersley, William John; Worm, Steven; Baber, Mark; Bainbridge, Robert; Buchmuller, Oliver; Burton, Darren; Colling, David; Cripps, Nicholas; Cutajar, Michael; Dauncey, Paul; Davies, Gavin; Della Negra, Michel; Ferguson, William; Fulcher, Jonathan; Futyan, David; Gilbert, Andrew; Guneratne Bryer, Arlo; Hall, Geoffrey; Hatherell, Zoe; Hays, Jonathan; Iles, Gregory; Jarvis, Martyn; Karapostoli, Georgia; Kenzie, Matthew; Lane, Rebecca; Lucas, Robyn; Lyons, Louis; Magnan, Anne-Marie; Marrouche, Jad; Mathias, Bryn; Nandi, Robin; Nash, Jordan; Nikitenko, Alexander; Pela, Joao; Pesaresi, Mark; Petridis, Konstantinos; Pioppi, Michele; Raymond, David Mark; Rogerson, Samuel; Rose, Andrew; Seez, Christopher; Sharp, Peter; Sparrow, Alex; Tapper, Alexander; Vazquez Acosta, Monica; Virdee, Tejinder; Wakefield, Stuart; Wardle, Nicholas; Cole, Joanne; Hobson, Peter R; Khan, Akram; Kyberd, Paul; Leggat, Duncan; Leslie, Dawn; Martin, William; Reid, Ivan; Symonds, Philip; Teodorescu, Liliana; Turner, Mark; Dittmann, Jay; Hatakeyama, Kenichi; Kasmi, Azeddine; Liu, Hongxuan; Scarborough, Tara; Charaf, Otman; Cooper, Seth; Henderson, Conor; Rumerio, Paolo; Avetisyan, Aram; Bose, Tulika; Fantasia, Cory; Heister, Arno; Lawson, Philip; Lazic, Dragoslav; Rohlf, James; Sperka, David; St John, Jason; Sulak, Lawrence; Alimena, Juliette; Bhattacharya, Saptaparna; Christopher, Grant; Cutts, David; Demiragli, Zeynep; Ferapontov, Alexey; Garabedian, Alex; Heintz, Ulrich; Jabeen, Shabnam; Kukartsev, Gennadiy; Laird, Edward; Landsberg, Greg; Luk, Michael; Narain, Meenakshi; Segala, Michael; Sinthuprasith, Tutanon; Speer, Thomas; Swanson, Joshua; Breedon, Richard; Breto, Guillermo; Calderon De La Barca Sanchez, Manuel; Chauhan, Sushil; Chertok, Maxwell; Conway, John; Conway, Rylan; Cox, Peter Timothy; Erbacher, Robin; Gardner, Michael; Ko, Winston; Kopecky, Alexandra; Lander, Richard; Miceli, Tia; Pellett, Dave; Pilot, Justin; Ricci-Tam, Francesca; Rutherford, Britney; Searle, Matthew; Shalhout, Shalhout; Smith, John; Squires, Michael; Tripathi, Mani; Wilbur, Scott; Yohay, Rachel; Andreev, Valeri; Cline, David; Cousins, Robert; Erhan, Samim; Everaerts, Pieter; Farrell, Chris; Felcini, Marta; Hauser, Jay; Ignatenko, Mikhail; Jarvis, Chad; Rakness, Gregory; Schlein, Peter; Takasugi, Eric; Valuev, Vyacheslav; Weber, Matthias; Babb, John; Clare, Robert; Ellison, John Anthony; Gary, J William; Hanson, Gail; Heilman, Jesse; Jandir, Pawandeep; Lacroix, Florent; Liu, Hongliang; Long, Owen Rosser; Luthra, Arun; Malberti, Martina; Nguyen, Harold; Shrinivas, Amithabh; Sturdy, Jared; Sumowidagdo, Suharyo; Wimpenny, Stephen; Andrews, Warren; Branson, James G; Cerati, Giuseppe Benedetto; Cittolin, Sergio; D'Agnolo, Raffaele Tito; Evans, David; Holzner, André; Kelley, Ryan; Kovalskyi, Dmytro; Lebourgeois, Matthew; Letts, James; Macneill, Ian; Padhi, Sanjay; Palmer, Christopher; Pieri, Marco; Sani, Matteo; Sharma, Vivek; Simon, Sean; Sudano, Elizabeth; Tadel, Matevz; Tu, Yanjun; Vartak, Adish; Wasserbaech, Steven; Würthwein, Frank; Yagil, Avraham; Yoo, Jaehyeok; Barge, Derek; Campagnari, Claudio; Danielson, Thomas; Flowers, Kristen; Geffert, Paul; George, Christopher; Golf, Frank; Incandela, Joe; Justus, Christopher; Magaña Villalba, Ricardo; Mccoll, Nickolas; Pavlunin, Viktor; Richman, Jeffrey; Rossin, Roberto; Stuart, David; To, Wing; West, Christopher; Apresyan, Artur; Bornheim, Adolf; Bunn, Julian; Chen, Yi; Di Marco, Emanuele; Duarte, Javier; Kcira, Dorian; Mott, Alexander; Newman, Harvey B; Pena, Cristian; Rogan, Christopher; Spiropulu, Maria; Timciuc, Vladlen; Wilkinson, Richard; Xie, Si; Zhu, Ren-Yuan; Azzolini, Virginia; Calamba, Aristotle; Carroll, Ryan; Ferguson, Thomas; Iiyama, Yutaro; Jang, Dong Wook; Paulini, Manfred; Russ, James; Vogel, Helmut; Vorobiev, Igor; Cumalat, John Perry; Drell, Brian Robert; Ford, William T; Gaz, Alessandro; Luiggi Lopez, Eduardo; Nauenberg, Uriel; Smith, James; Stenson, Kevin; Ulmer, Keith; Wagner, Stephen Robert; Alexander, James; Chatterjee, Avishek; Eggert, Nicholas; Gibbons, Lawrence Kent; Hopkins, Walter; Khukhunaishvili, Aleko; Kreis, Benjamin; Mirman, Nathan; Nicolas Kaufman, Gala; Patterson, Juliet Ritchie; Ryd, Anders; Salvati, Emmanuele; Sun, Werner; Teo, Wee Don; Thom, Julia; 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Loveless, Richard; Mohapatra, Ajit; Ojalvo, Isabel; Perry, Thomas; Pierro, Giuseppe Antonio; Polese, Giovanni; Ross, Ian; Sakharov, Alexandre; Sarangi, Tapas; Savin, Alexander; Smith, Wesley H

    2014-10-16

    Measurements of the inclusive jet cross section with the anti-$k_t$ clustering algorithm are presented for two radius parameters, R=0.5 and 0.7. They are based on data from LHC proton-proton collisions at $\\sqrt{s}$ = 7 TeV corresponding to an integrated luminosity of 5.0 inverse-femtobarns collected with the CMS detector in 2011. The ratio of these two measurements is obtained as a function of the rapidity and transverse momentum of the jets. Significant discrepancies are found comparing the data to leading-order simulations and to fixed-order calculations at next-to-leading order, corrected for nonperturbative effects, whereas simulations with next-to-leading-order matrix elements matched to parton showers describe the data best.

  3. An evaluation with the Fourier Amplitude Sensitivity Test (FAST) of which land-surface parameters are of greatest importance in atmospheric modeling

    Science.gov (United States)

    Collins, Dan C.; Avissar, Roni

    1994-01-01

    Land-surface parameterizations based on a statistical-dynamical have been suggested recently to improve the representation of the surface forcing from heterogeneous land in atmospheric models. With this approach, land-surface characteristics are prescribed by probability density functions (PDFs) rather than single 'representative' values as in 'big-leaf' parameterizations. Yet the use of many PDFs results in an increased computational burden and requires the complex problem of representing covariances between PDFs to be addressed. In this study, a sensitivity analysis of a land-surface parameterization for atmospheric modeling was performed to evaluate the surface parameters most important to the variability of surface heat fluxes. The Fourier amplitude sensitivity test (FAST) used for this analysis determines the relative contribution of individual input parameters to the variance of energy fluxes resulting from a heterogeneous surface. By simultaneously varying all parameters according to their individual probability density functions, the number of computations needed is very much reduced by this technique. This analysis demonstrates that most of the variability of surface heat fluxes may be described by the distributions of relative stomatal conductance and surface roughness. Thus, the statistical-dynamical approach may be simplified by the use of only these two probability density functions.

  4. Will an unsupervised self-testing strategy for HIV work in health care workers of South Africa? A cross sectional pilot feasibility study.

    Directory of Open Access Journals (Sweden)

    Nitika Pant Pai

    Full Text Available BACKGROUND: In South Africa, stigma, discrimination, social visibility and fear of loss of confidentiality impede health facility-based HIV testing. With 50% of adults having ever tested for HIV in their lifetime, private, alternative testing options are urgently needed. Non-invasive, oral self-tests offer a potential for a confidential, unsupervised HIV self-testing option, but global data are limited. METHODS: A pilot cross-sectional study was conducted from January to June 2012 in health care workers based at the University of Cape Town, South Africa. An innovative, unsupervised, self-testing strategy was evaluated for feasibility; defined as completion of self-testing process (i.e., self test conduct, interpretation and linkage. An oral point-of-care HIV test, an Internet and paper-based self-test HIV applications, and mobile phones were synergized to create an unsupervised strategy. Self-tests were additionally confirmed with rapid tests on site and laboratory tests. Of 270 health care workers (18 years and above, of unknown HIV status approached, 251 consented for participation. FINDINGS: Overall, about 91% participants rated a positive experience with the strategy. Of 251 participants, 126 evaluated the Internet and 125 the paper-based application successfully; completion rate of 99.2%. All sero-positives were linked to treatment (completion rate:100% (95% CI, 66.0-100. About half of sero-negatives were offered counselling on mobile phones; completion rate: 44.6% (95% CI, 38.0-51.0. A majority of participants (78.1% were females, aged 18-24 years (61.4%. Nine participants were found sero-positive after confirmatory tests (prevalence 3.6% 95% CI, 1.8-6.9. Six of nine positive self-tests were accurately interpreted; sensitivity: 66.7% (95% CI, 30.9-91.0; specificity:100% (95% CI, 98.1-100. INTERPRETATION: Our unsupervised self-testing strategy was feasible to operationalize in health care workers in South Africa. Linkages were successfully

  5. Cross sectional study of performance indicators for English Primary Care Trusts: testing construct validity and identifying explanatory variables

    Directory of Open Access Journals (Sweden)

    Lilford Richard

    2006-06-01

    Full Text Available Abstract Background The performance of Primary Care Trusts in England is assessed and published using a number of different performance indicators. Our study has two broad purposes. Firstly, to find out whether pairs of indicators that purport to measure similar aspects of quality are correlated (as would be expected if they are both valid measures of the same construct. Secondly, we wanted to find out whether broad (global indicators correlated with any particular features of Primary Care Trusts, such as expenditure per capita. Methods Cross sectional quantitative analysis using data from six 2004/05 PCT performance indicators for 303 English Primary Care Trusts from four sources in the public domain: Star Rating, aggregated Quality and Outcomes Framework scores, Dr Foster mortality index, Dr Foster equity index (heart by-pass and hip replacements, NHS Litigation Authority Risk Management standards and Patient Satisfaction scores from the Star Ratings. Forward stepwise multiple regression analysis to determine the effect of Primary Care Trust characteristics on performance. Results Star Rating and Quality and Outcomes Framework total, both summary measures of global quality, were not correlated with each other (F = 0.66, p = 0.57. There were however positive correlations between Quality and Outcomes Framework total and patient satisfaction (r = 0.61, p Conclusion Performance assessment in healthcare remains on the Government's agenda, with new core and developmental standards set to replace the Star Ratings in 2006. Yet the results of this analysis provide little evidence that the current indicators have sufficient construct validity to measure the underlying concept of quality, except when the specific area of screening is considered.

  6. Improvements in Obstacle Clearance Parameters and Reaction Time Over a Series of Obstacles Revealed After Five Repeated Testing Sessions in Older Adults.

    Science.gov (United States)

    Jehu, Deborah A; Lajoie, Yves; Paquet, Nicole

    2017-12-21

    The purpose of this study was to investigate obstacle clearance and reaction time parameters when crossing a series of six obstacles in older adults. A second aim was to examine the repeated exposure of this testing protocol once per week for 5 weeks. In total, 10 older adults (five females; age: 67.0 ± 6.9 years) walked onto and over six obstacles of varying heights (range: 100-200 mm) while completing no reaction time, simple reaction time, and choice reaction time tasks once per week for 5 weeks. The highest obstacles elicited the lowest toe clearance, and the first three obstacles revealed smaller heel clearance compared with the last three obstacles. Dual tasking negatively impacted obstacle clearance parameters when information processing demands were high. Longer and less consistent time to completion was observed in Session 1 compared with Sessions 2-5. Finally, improvements in simple reaction time were displayed after Session 2, but choice reaction time gradually improved and did not reach a plateau after repeated testing.