WorldWideScience

Sample records for test ip-582-d irradiation

  1. 21 CFR 582.5580 - D-Pantothenyl alcohol.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false D-Pantothenyl alcohol. 582.5580 Section 582.5580 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL... Supplements 1 § 582.5580 D-Pantothenyl alcohol. (a) Product. D-Pantothenyl alcohol. (b) Conditions of use...

  2. 21 CFR 582.5953 - Vitamin D3.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Vitamin D3. 582.5953 Section 582.5953 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS... 1 § 582.5953 Vitamin D3. (a) Product. Vitamin D3. (b) Conditions of use. This substance is generally...

  3. 21 CFR 582.5950 - Vitamin D2.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Vitamin D2. 582.5950 Section 582.5950 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS... 1 § 582.5950 Vitamin D2. (a) Product. Vitamin D2. (b) Conditions of use. This substance is generally...

  4. An Installation of IPS Bypass Line at the Fuel Test Loop

    Energy Technology Data Exchange (ETDEWEB)

    Choi, Ho Young; Ahn, G. H.; Lee, M.; Kim, M. S.; Cho, S. H.; Han, J. S.; Hur, S. O. [KAERI, Daejeon (Korea, Republic of)

    2010-12-15

    The Fuel Test Loop(FTL) was installed for the national goal of self-supporting technology in the field of design and construction of nuclear power plant. The FTL with the fuel irradiation equipment is essential in developing, improving and inspecting the fuel of CANDU type or PWR type nuclear power plant. The FTL should be operated at the same conditions of commercial nuclear power plant such as temperature, pressure, flow rate, neutron flux and so on. Starting designing in December 2001, the FTL was installed from March 2007 to August 2008. Especially the In Pile Section(IPS) was installed at IR1 hole in August 2008. Until September 2009 after loading the test fuel, a series of power escalation tests (LSD, CSB1, CSB2, HSB, HOP) were conducted. And it was operated at the condition of CSB2 for the 8 cycles from October 2009 to July 2010. But it could not be normally operated in early 2010, because the high radiation released from irradiated materials due to the worn down bearing of main cooling pump. So, we removed the IPS and installed a newly designed IPS bypass line to prevent increasing high radiation. In this report we will present preliminary works, main works processes, devices of making work environments, a designing and manufacturing of IPS bypass line and a rack of IPS, installing know-hows, problems and solutions broke out during the work etc. We believe that our efforts to complete successful installing and operating of the FTL system will contribute for the efficient utilization of HANARO

  5. Development of a Device for a Material Irradiation Test in the OR Test Hole

    Energy Technology Data Exchange (ETDEWEB)

    Cho, Man Soon; Kang, Y. H.; Kim, B. G.; Choo, K. N.; Sohn, J. M.; Shin, Y. T.; Park, S. J.; Seo, C. K

    2008-05-15

    To develop a technology and a device for the irradiation test for utilization of the OR/IP holes according to the various requirements of users, the properties of the OR/IP holes were investigated and an irradiation device for the OR hole was designed and fabricated. The OR-4, 5 and the IP-9, 10, 11 holes were selected as those suitable to irradiation tests among the test holes located in the out core area. The conceptual design was performed to design a device to irradiate materials using the OR and IP holes. The capsule for the OR holes is fixed by pressing the protection tube using a clamping device, on the other hand the IP capsule is inserted in the hole without a special clamping device. In the basic design of the irradiation device for the OR hole, the capsules having the outside diameter of 50, 52, 54, 56mm were reviewed theoretically to investigate if they meet the hydraulic and vibration conditions required in the HANARO. The results of the pressure drop test showed that the 3 kinds of capsules having diameter of 52, 54, 56mm satisfied the requirement for the pressure difference and flow rate in HANARO. The capsule of {phi}56mm out of the above three satisfied the vibration condition and was finally selected giving consideration of a capacity of specimens. The capsule having a diameter of {phi}56mm was fabricated and the flow rate was measured. Using the velocity data measured at the out-core facility, the heat transfer coefficient, and the temperature on the surface of the capsule was evaluated to confirm it less than the ONB temperature. As a result, the capsule of {phi}56mm was selected for the irradiation test at the OR holes.

  6. IP and resistivity survey at the INEL cold test pit

    International Nuclear Information System (INIS)

    Frangos, W.

    1997-01-01

    Induced polarization (IP) is a technique for detection of diffuse occurrences of metallic material. The Idaho National Laboratory (INEL) Cold Test Pit (CTP) has been carefully constructed to simulate stored hazardous waste occurrences. IP and resistivity surveys of the CTP show a very strong IP response and a modest resistivity response associated with the simulated waste. Several false positive resistivity anomalies are noted. 2-D inversion of the data accurately determine the lateral limits of the waste zone. The depth of burial indicated is deeper than reported by the construction engineers. Limited depth extent is recognized, in distinction to results from other, resistivity-based, methods, but it also appears too deep. IP holds promise as a method for locating buried waste

  7. Testbeam and laboratory test results of irradiated 3D CMS pixel detectors

    Energy Technology Data Exchange (ETDEWEB)

    Bubna, Mayur [Purdue University, Department of Physics, West Lafayette, IN 47907-1396 (United States); Purdue University, School of Electrical and Computer Engineering, West Lafayette, IN 47907-1396 (United States); Alagoz, Enver, E-mail: enver.alagoz@cern.ch [Purdue University, Department of Physics, West Lafayette, IN 47907-1396 (United States); Cervantes, Mayra; Krzywda, Alex; Arndt, Kirk [Purdue University, Department of Physics, West Lafayette, IN 47907-1396 (United States); Obertino, Margherita; Solano, Ada [Istituto Nazionale di Fisica Nucleare, Sezione di Torino, 10125 Torino (Italy); Dalla Betta, Gian-Franco [INFN Padova (Gruppo Collegato di Trento) (Italy); Dipartimento di Ingegneria e Scienzadella Informazione, Universitá di Trento, I-38123 Povo di Trento (Italy); Menace, Dario; Moroni, Luigi [Istituto Nazionale di Fisica Nucleare, Sezione di Milano Bicocca (Italy); Universitá degli Studi di Milano Bicocca, 20126 Milano (Italy); Uplegger, Lorenzo; Rivera, Ryan [Fermi National Accelerator Laboratory, Batavia, IL 60510-0500 (United States); Osipenkov, Ilya [Texas A and M University, Department of Physics, College Station, TX 77843-4242 (United States); Andresen, Jeff [Fermi National Accelerator Laboratory, Batavia, IL 60510-0500 (United States); Bolla, Gino; Bortoletto, Daniela [Purdue University, Department of Physics, West Lafayette, IN 47907-1396 (United States); Boscardin, Maurizio [Centro per i Materiali e i Microsistemi Fondazione Bruno Kessler (FBK), Trento, I-38123 Povo di Trento (Italy); Marie Brom, Jean [Strasbourg IPHC, Institut Pluriedisciplinaire Hubert Curien, F-67037 Strasbourg Cedex (France); Brosius, Richard [State University of New York at Buffalo (SUNY), Department of Physics, Buffalo, NY 14260-1500 (United States); Chramowicz, John [Fermi National Accelerator Laboratory, Batavia, IL 60510-0500 (United States); and others

    2013-12-21

    The CMS silicon pixel detector is the tracking device closest to the LHC p–p collisions, which precisely reconstructs the charged particle trajectories. The planar technology used in the current innermost layer of the pixel detector will reach the design limit for radiation hardness at the end of Phase I upgrade and will need to be replaced before the Phase II upgrade in 2020. Due to its unprecedented performance in harsh radiation environments, 3D silicon technology is under consideration as a possible replacement of planar technology for the High Luminosity-LHC or HL-LHC. 3D silicon detectors are fabricated by the Deep Reactive-Ion-Etching (DRIE) technique which allows p- and n-type electrodes to be processed through the silicon substrate as opposed to being implanted through the silicon surface. The 3D CMS pixel devices presented in this paper were processed at FBK. They were bump bonded to the current CMS pixel readout chip, tested in the laboratory, and testbeams carried out at FNAL with the proton beam of 120 GeV/c. In this paper we present the laboratory and beam test results for the irradiated 3D CMS pixel devices. -- Highlights: •Pre-irradiation and post-irradiation electrical properties of 3D sensors and 3D diodes from various FBK production batches were measured and analyzed. •I–T measurements of gamma irradiated diodes were analyzed to understand leakage current generation mechanism in 3D diodes. •Laboratory measurements: signal to noise ratio and charge collection efficiency of 3D sensors before and after irradiation. •Testbeam measurements: pre- and post-irradiation pixel cell efficiency and position resolution of 3D sensors.

  8. IP validation in remote microelectronics testing

    Science.gov (United States)

    Osseiran, Adam; Eshraghian, Kamran; Lachowicz, Stefan; Zhao, Xiaoli; Jeffery, Roger; Robins, Michael

    2004-03-01

    This paper presents the test and validation of FPGA based IP using the concept of remote testing. It demonstrates how a virtual tester environment based on a powerful, networked Integrated Circuit testing facility, aimed to complement the emerging Australian microelectronics based research and development, can be employed to perform the tasks beyond the standard IC test. IC testing in production consists in verifying the tested products and eliminating defective parts. Defects could have a number of different causes, including process defects, process migration and IP design and implementation errors. One of the challenges in semiconductor testing is that while current fault models are used to represent likely faults (stuck-at, delay, etc.) in a global context, they do not account for all possible defects. Research in this field keeps growing but the high cost of ATE is preventing a large community from accessing test and verification equipment to validate innovative IP designs. For these reasons a world class networked IC teletest facility has been established in Australia under the support of the Commonwealth government. The facility is based on a state-of-the-art semiconductor tester operating as a virtual centre spanning Australia and accessible internationally. Through a novel approach the teletest network provides virtual access to the tester on which the DUT has previously been placed. The tester software is then accessible as if the designer is sitting next to the tester. This paper presents the approach used to test and validate FPGA based IPs using this remote test approach.

  9. Technology Implementation Plan: Irradiation Testing and Qualification for Nuclear Thermal Propulsion Fuel

    Energy Technology Data Exchange (ETDEWEB)

    Harrison, Thomas J. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Howard, Richard H. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Rader, Jordan D. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2017-09-01

    This document is a notional technology implementation plan (TIP) for the development, testing, and qualification of a prototypic fuel element to support design and construction of a nuclear thermal propulsion (NTP) engine, specifically its pre-flight ground test. This TIP outlines a generic methodology for the progression from non-nuclear out-of-pile (OOP) testing through nuclear in-pile (IP) testing, at operational temperatures, flows, and specific powers, of an NTP fuel element in an existing test reactor. Subsequent post-irradiation examination (PIE) will occur in existing radiological facilities. Further, the methodology is intended to be nonspecific with respect to fuel types and irradiation or examination facilities. The goals of OOP and IP testing are to provide confidence in the operational performance of fuel system concepts and provide data to program leadership for system optimization and fuel down-selection. The test methodology, parameters, collected data, and analytical results from OOP, IP, and PIE will be documented for reference by the NTP operator and the appropriate regulatory and oversight authorities. Final full-scale integrated testing would be performed separately by the reactor operator as part of the preflight ground test.

  10. Status on the construction of the fuel irradiation test facility

    International Nuclear Information System (INIS)

    Park, Kook Nam; Sim, Bong Shick; Lee, Chung Young; Yoo, Seong Yeon

    2005-01-01

    As a facility to examine general performance of nuclear fuel under irradiation condition in HANARO, Fuel Test Loop(FTL) has been developed which can accommodate 3 fuel pins at the core irradiation hole(IR1 hole) taking consideration user's test requirement. 3-Pin FTL consists of In-Pile Test Section (IPS) and Out-of- Pile System (OPS). Test condition in IPS such as pressure, temperature and the water quality, can be controlled by OPS. 3-Pin FTL Conceptual design was set up in 2001 and had completed detail design including a design requirement and basic Piping and Instrument Diagram (P and ID) in 2004. The safety analysis report was prepared and submitted in early 2005 to the regulatory body(KINS) for review and approval of FTL. In 2005, the development team is going to purchase and manufacture hardware and make a contract for construction work. In 2006, the development team is going to install an FTL system performance test shall be done as a part of commissioning. After a 3-Pin FTL development which is expected to be finished by the 2007, FTL will be used for the irradiation test of the new PWR-type fuel and the usage of HANARO will be enhanced

  11. Apparatus of irradiation of steel test pieces in the Marcoule pile G 1; Dispositifs d'irradiation d'eprouvettes d'acier dans la pile G 1 de Marcoule

    Energy Technology Data Exchange (ETDEWEB)

    Marinot, R; Wallet, Ph [Commissariat a l' Energie Atomique, Saclay (France).Centre d' Etudes Nucleaires

    1960-07-01

    Test pieces of steel were irradiated in the reactor G1 at Marcoule, in convectors replacing fuel elements, and in vertical channels in furnace-heated containers. The apparatus designed for this irradiation is described: containers, converter-rods, suspension fixtures and clamps, temperature measurement devices, lead castles and unloading set-ups. (author) [French] Des eprouvettes d'acier ont ete irradiees dans le reacteur G1 de Marcoule dans des convertisseurs mis a la place d'elements combustibles, et dans des canaux verticaux, en conteneurs chauffes par four. Nous decrivons l'appareillage etudie pour cette irradiation: conteneurs, barreaux-convertisseurs, dispositifs de suspension et d'amarrage, dispositifs de regulation et de mesure de temperature, chateaux de plomb et montages de defournement. (auteur)

  12. Genotoxicity test of irradiated spice mixture by dominant lethal test

    Energy Technology Data Exchange (ETDEWEB)

    Barna, J

    1986-03-01

    Dominant lethal test (DLT) was performed in Sprague Dawley male rats prefed with 25% irradiated spice mixture which was composed of 55% non-pungent ground paprika, 14% black pepper, 9% allspice, 9% coriander, 7% marjoram, 4% cumin, 2% nutmeg. Microbial count of the spice mixture was reduced with 15 kGy from a sup(60)Co source. Control groups received spice-free or untreated spice diet or were administered to cyclophosphamide i.p., respectively. DTL parameters altered significantly in the latter group but neither untreated nor irradiated spice mixture proved to be germ cell mutagens. 24 refs.; 8 figs.

  13. The design of in-pile test section for fuel test loop

    Energy Technology Data Exchange (ETDEWEB)

    Park, K. N.; Lee, J. M.; Shim, B. S.; Zee, D. Y.; Park, S. H.; Ahn, S. H.; Lee, J. Y.; Kim, Y. J. [KAERI, Taejon (Korea, Republic of)

    2004-07-01

    As an equipment for nuclear fuel's general performance irradiation test in HANARO, Fuel Test Loop(FTL) has been developed that can irradiate the pin to the maximum number of 3 at the core irradiation hole(IR1 hole) by considering for it's utility and user's irradiation requirement. 3-Pin FTL consists of In-Pile Test Section (IPS) and Out-of-Pile System (OPS). IPS consists for IPS Vessel assembly, In-Pool Piping, IPS Support, In-Pool Piping Support etc. Design that such IPS considers interference item consisted to do not bear in existing facilities by one. IVA that is connected to the OPS are controlled and regulated by means of system pressure, system temperature and the water quality. IPS Vessel assembly is consisted of outer pressure vessel, inner pressure vessel, IPS head, inner assembly and test fuel carrier. After 3-Pin FTL development which is expected to be finished by the 2006, FTL will be used for the irradiation test of the new PWR-type fuel and can maximize the usage of HANARO.

  14. A Study on the High Temperature Irradiation Test Possibility for the HANARO Outer Core Region

    Energy Technology Data Exchange (ETDEWEB)

    Kang, Young Hwan; Cho, M. S.; Choo, K. N.; Shin, Y. T.; Sohn, J. M.; Park, S. J.; Kim, B. G

    2008-01-15

    1. Information on the neutron flux levels and the gamma heat of the concerned test holes, which have been produced from a series of nuclear analysis and tests performed at KAERI since 1993, were collected and analyzed to develop the nuclear data for the concerned test holes of HANARO and to develop the new design concepts of a capsule for the high temperature irradiation devices. 2. From the literature survey and analysis about the system design characteristics of the new concepts of irradiation devices in the ATR and MIT reactor, U.S. and the JHR reactor, France, which are helpful in understanding the key issues for the on-going R and D programmes related to a SFR and a VHTR, the most important parameters for the design of high temperature irradiation devices are identified as the neutron spectrum, the heat generation density, the fuel and cladding temperature, and the coolant chemistry. 3. From the thermal analysis of a capsule by using a finite element program ANSYS, high temperature test possibility at the OR and IP holes of HANARO was investigated based on the data collected from a literature survey. The OR holes are recommended for the tests of the SFR and VHTR nuclear materials. The IP holes could be applicable for an intermediate temperature irradiation of the SWR and LMR materials. 4. A thermal analysis for the development of a capsule with a new configuration was also performed. The size of the center hole, which is located at the thermal media of a capsule, did not cause specimen temperature changes. The temperature differences are found to be less than 2%. The introduction of an additional gap in the thermal media was able to contribute to an increase in the specimen temperature by up to 27-90 %.

  15. The Assembly and Test of Pressure Vessel for Irradiation

    International Nuclear Information System (INIS)

    Park, Kook Nam; Lee, Jong Min; Youn, Young Jung; June, Hyung Kil; Ahn, Sung Ho; Lee, Kee Hong; Kim, Young Ki; Kennedy, Timothy C.

    2009-01-01

    The Fuel Test Loop(FTL) which is capable of an irradiation testing under a similar operating condition to those of PWR(Pressurized Water Reactor) and CANDU(CANadian Deuterium Uranium reactor) nuclear power plants has been developed and installed in HANARO, KAERI(Korea Atomic Energy Research Institute). It consists of In-Pile Section(IPS) and Out-of Pile System(OPS). The IPS, which is located inside the pool is divided into 3-parts: the in-pool pipes, the IVA(IPS Vessel Assembly) and the support structures. The test fuel is loaded inside a double wall, inner pressure vessel and outer pressure vessel, to keep the functionality of the reactor coolant pressure boundary. The IVA is manufactured by local company and the functional test and verification were done through pressure drop, vibration, hydraulic and leakage tests. The brazing technique for the instrument lines has been checked for its functionality and performance. An IVA has been manufactured by local technique and have finally tested under high temperature and high pressure. The IVA and piping did not experience leakage, as we have checked the piping, flanges, assembly parts. We have obtained good data during the three cycle test which includes a pressure test, pressure and temperature cycling, and constant temperature

  16. The Assembly and Test of Pressure Vessel for Irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Park, Kook Nam; Lee, Jong Min; Youn, Young Jung; June, Hyung Kil; Ahn, Sung Ho; Lee, Kee Hong; Kim, Young Ki [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of); Kennedy, Timothy C. [Oregon State University, Corvallis (United States)

    2009-02-15

    The Fuel Test Loop(FTL) which is capable of an irradiation testing under a similar operating condition to those of PWR(Pressurized Water Reactor) and CANDU(CANadian Deuterium Uranium reactor) nuclear power plants has been developed and installed in HANARO, KAERI(Korea Atomic Energy Research Institute). It consists of In-Pile Section(IPS) and Out-of Pile System(OPS). The IPS, which is located inside the pool is divided into 3-parts: the in-pool pipes, the IVA(IPS Vessel Assembly) and the support structures. The test fuel is loaded inside a double wall, inner pressure vessel and outer pressure vessel, to keep the functionality of the reactor coolant pressure boundary. The IVA is manufactured by local company and the functional test and verification were done through pressure drop, vibration, hydraulic and leakage tests. The brazing technique for the instrument lines has been checked for its functionality and performance. An IVA has been manufactured by local technique and have finally tested under high temperature and high pressure. The IVA and piping did not experience leakage, as we have checked the piping, flanges, assembly parts. We have obtained good data during the three cycle test which includes a pressure test, pressure and temperature cycling, and constant temperature.

  17. Apparatus of irradiation of steel test pieces in the Marcoule pile G 1; Dispositifs d'irradiation d'eprouvettes d'acier dans la pile G 1 de Marcoule

    Energy Technology Data Exchange (ETDEWEB)

    Marinot, R.; Wallet, Ph. [Commissariat a l' Energie Atomique, Saclay (France).Centre d' Etudes Nucleaires

    1960-07-01

    Test pieces of steel were irradiated in the reactor G1 at Marcoule, in convectors replacing fuel elements, and in vertical channels in furnace-heated containers. The apparatus designed for this irradiation is described: containers, converter-rods, suspension fixtures and clamps, temperature measurement devices, lead castles and unloading set-ups. (author) [French] Des eprouvettes d'acier ont ete irradiees dans le reacteur G1 de Marcoule dans des convertisseurs mis a la place d'elements combustibles, et dans des canaux verticaux, en conteneurs chauffes par four. Nous decrivons l'appareillage etudie pour cette irradiation: conteneurs, barreaux-convertisseurs, dispositifs de suspension et d'amarrage, dispositifs de regulation et de mesure de temperature, chateaux de plomb et montages de defournement. (auteur)

  18. Technical review on irradiation tests and post-irradiation examinations in JMTR

    International Nuclear Information System (INIS)

    2017-07-01

    The Japan Materials Testing Reactor (JMTR) has been contributing to various R and D activities in the nuclear research such as the fundamental research of nuclear materials/ fuels, safety research and development of power reactors, radio isotope (RI) production since its beginning of the operation in 1968. Irradiation technologies and post irradiation examination (PIE) technologies are the important factors for irradiation test research. Moreover, these technologies induce the breakthrough in area of nuclear research. JMTR has been providing unique capabilities for the irradiation test research for about 40 years since 1968. In future, any needs for irradiation test research used irradiation test reactors will continue, such as R and D of generation 4 power reactors, fundamental research of materials/fuels, RI production. Now, decontamination and new research reactor construction are common issue in the world according to aging. This situation is the same in Japan. This report outlines irradiation and PIE technologies developed at JMTR in 40 years to contribute to the technology transfer and human resource development. We hope that this report will be used for the new research rector design as well as the irradiation test research and also used for the human resource development of nuclear engineers in future. (author)

  19. ELRIS2D: A MATLAB Package for the 2D Inversion of DC Resistivity/IP Data

    Science.gov (United States)

    Akca, Irfan

    2016-04-01

    ELRIS2D is an open source code written in MATLAB for the two-dimensional inversion of direct current resistivity (DCR) and time domain induced polarization (IP) data. The user interface of the program is designed for functionality and ease of use. All available settings of the program can be reached from the main window. The subsurface is discre-tized using a hybrid mesh generated by the combination of structured and unstructured meshes, which reduces the computational cost of the whole inversion procedure. The inversion routine is based on the smoothness constrained least squares method. In order to verify the program, responses of two test models and field data sets were inverted. The models inverted from the synthetic data sets are consistent with the original test models in both DC resistivity and IP cases. A field data set acquired in an archaeological site is also used for the verification of outcomes of the program in comparison with the excavation results.

  20. Manufacturing of In-Pile Test Section(IPS) Mock-up for the 3-Pin Fuel Test Loop

    Energy Technology Data Exchange (ETDEWEB)

    Lee, J. M.; Park, K. N.; Chi, D. Y. (and others)

    2005-10-15

    Manufacturing process of IPS Mock-up was initiated in late of 2003 with DAEWOO Precision industries Company. Manufacturing drawings due to detail drawings are composed of Outer assembly and Inner assembly. Welding of IPS Mock-up was performed by the GMAW(Gas Metal Arc Welding) process. After the welding process, non-destructive examination was conducted. Leak test was performed to the Main cooling water part and Neon gas inter-space gap part by the He gas injection with the pressure of 6.0 kg{sub f}/cm{sup 2} and 30 minutes holding time. the result was shown that there was no leak at the Neon gas inter-space gap part but leak was occurred at Main cooling water part according to imperfect screw of purge plug. so, it was re-finished and test was performed to certify the leak tightness. To satisfy the HANARO Limiting Operation Condition, IPS should be tested ahead of installation at the HANARO reactor by the use of test facilities. IPS Mock-up and its test facilities will be designed and used for the test of 'HANARO flow tube pressure drop', 'IPS inner pressure drop' and 'IPS inner vibration'.

  1. Review Report on the Design of In-Pile Test Section(IPS)

    International Nuclear Information System (INIS)

    Lee, Jong Min; Park, Kook Nam; Shim, Bong Sik; Lee, Chung Young; Chi, Dae Young; Park, Su Ki; Ahn, Sung Ho; Kim, Young Ki; Lee, Kye Hong; Kim, Kwan Hyun

    2009-01-01

    The In-Pile Test Section(IPS) accommodating fuel pins has loaded IR-1 hole in HANARO has double pressure vessel for the design conditions of 350 deg. C, 17.5 MPa and is composed of outer assembly and inner assembly. Dummy fuel, dummy fuel supports and Top flange are the main components in inner assembly and inner pressure vessel, outer pressure vessel and head are the components in outer assembly. The IPS at current status has dummy fuels and confirm the requirements for the IPS design improvements during the design, manufacturing and installation process. Head, Top Flange, Instrumentation Feed through, Lifting Eye, Fuel Carrier Leg, Retainer and Nozzle cover are the main parts that the design needs to be changed. This report suggest the needs for the IPS design modification and it would be reflected to the new IPS design which would accommodating test fuel pins

  2. Review Report on the Design of In-Pile Test Section(IPS)

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Jong Min; Park, Kook Nam; Shim, Bong Sik; Lee, Chung Young; Chi, Dae Young; Park, Su Ki; Ahn, Sung Ho; Kim, Young Ki; Lee, Kye Hong; Kim, Kwan Hyun

    2009-01-15

    The In-Pile Test Section(IPS) accommodating fuel pins has loaded IR-1 hole in HANARO has double pressure vessel for the design conditions of 350 deg. C, 17.5 MPa and is composed of outer assembly and inner assembly. Dummy fuel, dummy fuel supports and Top flange are the main components in inner assembly and inner pressure vessel, outer pressure vessel and head are the components in outer assembly. The IPS at current status has dummy fuels and confirm the requirements for the IPS design improvements during the design, manufacturing and installation process. Head, Top Flange, Instrumentation Feed through, Lifting Eye, Fuel Carrier Leg, Retainer and Nozzle cover are the main parts that the design needs to be changed. This report suggest the needs for the IPS design modification and it would be reflected to the new IPS design which would accommodating test fuel pins.

  3. Post-irradiation examination and R and D programs using irradiated fuels at KAERI

    International Nuclear Information System (INIS)

    Chun, Yong Bum; Min, Duck Kee; Kim, Eun Ka and others

    2000-12-01

    This report describes the Post-Irradiation Examination(PIE) and R and D programs using irradiated fuels at KAERI. The objectives of post-irradiation examination (PIE) for the PWR irradiated fuels, CANDU fuels, HANARO fuels and test fuel materials are to verify the irradiation performance and their integrity as well as to construct a fuel performance data base. The comprehensive utilization program of the KAERI's post-irradiation examination related nuclear facilities such as Post-Irradiation Examination Facility (PIEF), Irradiated Materials Examination Facility (IMEF) and HANARO is described

  4. Post-irradiation examination and R and D programs using irradiated fuels at KAERI

    International Nuclear Information System (INIS)

    Chun, Yong Bum; So, Dong Sup; Lee, Byung Doo; Lee, Song Ho; Min, Duck Kee

    2001-09-01

    This report describes the Post-Irradiation Examination(PIE) and R and D programs using irradiated fuels at KAERI. The objectives of post-irradiation examination (PIE) for the PWR irradiated fuels, CANDU fuels, HANARO fuels and test fuel materials are to verify the irradiation performance and their integrity as well as to construct a fuel performance data base. The comprehensive utilization program of the KAERI's post-irradiation examination related nuclear facilities such as Post-Irradiation Examination Facility (PIEF), Irradiated Materials Examination Facility (IMEF) and HANARO is described

  5. 3-D spectral IP imaging: Non-invasive characterization of contaminant plumes. 1998 annual progress report

    International Nuclear Information System (INIS)

    Lesmes, D.; Morgan, F.D.; Rodi, W.

    1998-01-01

    annual SAGEEP conference (Shi et al., 1998). The authors have developed algorithms for forward modeling and inversion of spectral IP data in 3-D media. The algorithms accommodate a general earth model with a complex electrical conductivity as a function of frequency and 3-D spatial position. Using regularization and optimization techniques, the inversion algorithm obtains a 3-D image of resistivity amplitude and phase for each frequency contained in the data set. They have begun testing their algorithms on synthetic data generated from a simple model of a contaminant plume. The complex resistivity parameters of the background medium and plume are based on the laboratory results described above.'

  6. Irradiation test and performance evaluation of DUPIC fuel

    International Nuclear Information System (INIS)

    Yang, Myung Seung; Song, K. C.; Moon, J. S.

    2002-05-01

    The objective of the project is to establish the performance evaluation system of DUPIC fuel during the Phase II R and D. In order to fulfil this objectives, irradiation test of DUPIC fuel was carried out in HANARO using the non-instrumented and SPND-instrumented rig. Also, the analysis on the in-reactor behavior analysis of DUPIC fuel, out-pile test using simulated DUPIC fuel as well as performance and integrity assessment in a commercial reactor were performed during this Phase. The R and D results of the Phase II are summarized as follows : - Performance evaluation of DUPIC fuel via irradiation test in HANARO - Post irradiation examination of irradiated fuel and performance analysis - Development of DUPIC fuel performance code (modified ELESTRES) considering material properties of DUPIC fuel - Irradiation behavior and integrity assessment under the design power envelope of DUPIC fuel - Foundamental technology development of thermal/mechanical performance evaluation using ANSYS (FEM package)

  7. IPS – A SYSTEM FOR REAL-TIME NAVIGATION AND 3D MODELING

    Directory of Open Access Journals (Sweden)

    D. Grießbach

    2012-07-01

    Full Text Available fdaReliable navigation and 3D modeling is a necessary requirement for any autonomous system in real world scenarios. German Aerospace Center (DLR developed a system providing precise information about local position and orientation of a mobile platform as well as three-dimensional information about its environment in real-time. This system, called Integral Positioning System (IPS can be applied for indoor environments and outdoor environments. To achieve high precision, reliability, integrity and availability a multi-sensor approach was chosen. The important role of sensor data synchronization, system calibration and spatial referencing is emphasized because the data from several sensors has to be fused using a Kalman filter. A hardware operating system (HW-OS is presented, that facilitates the low-level integration of different interfaces. The benefit of this approach is an increased precision of synchronization at the expense of additional engineering costs. It will be shown that the additional effort is leveraged by the new design concept since the HW-OS methodology allows a proven, flexible and fast design process, a high re-usability of common components and consequently a higher reliability within the low-level sensor fusion. Another main focus of the paper is on IPS software. The DLR developed, implemented and tested a flexible and extensible software concept for data grabbing, efficient data handling, data preprocessing (e.g. image rectification being essential for thematic data processing. Standard outputs of IPS are a trajectory of the moving platform and a high density 3D point cloud of the current environment. This information is provided in real-time. Based on these results, information processing on more abstract levels can be executed.

  8. The CANopen Controller IP Core: Implementation, Synthesis and Test Results

    Science.gov (United States)

    Caramia, Maurizio; Bolognino, Luca; Montagna, Mario; Tosi, Pietro; Errico, Walter; Bigongiari, Franco; Furano, Gianluca

    2011-08-01

    This paper will describe the implementation and test results of the CANopen Controller IP Core (CCIPC) implemented by Thales Alenia Space and SITAEL Aerospace with the support of ESA in the frame of the EXOMARS Project. The CCIPC is a configurable VHDL implementation of the CANOPEN protocol [1]; it is foreseen to be used as CAN bus slave controller within the EXOMARS Entry Descending and Landing Demonstrato Module (EDM) and Rover Module. The CCIPC features, configuration capability, synthesis and test results will be described and the evidence of the state of maturity of this innovative IP core will be demonstrated.

  9. CONTRIBUTION OF HANARO IRRADIATION TECHNOLOGIES TO NATIONAL NUCLEAR R&D

    Directory of Open Access Journals (Sweden)

    KEE NAM CHOO

    2014-08-01

    Full Text Available HANARO is a multipurpose research reactor located at the Korea Atomic Energy Research Institute (KAERI. Since the commencement of its operation in 1995, various neutron irradiation facilities, such as rabbit irradiation facilities, fuel test loop (FTL facilities, capsule irradiation facilities, and neutron transmutation doping (NTD facilities, have been developed and actively utilized for various nuclear material irradiation tests requested by users from research institutes, universities, and industries. Most irradiation tests have been related to national R&D relevant to present nuclear power reactors such as the ageing management and safety evaluation of the components. Based on the accumulated experience as well as the sophisticated requirements of users, HANARO has recently supported national R&D projects relevant to new nuclear systems including the System-integrated Modular Advanced Reactor (SMART, research reactors, and future nuclear systems. This paper documents the current state and utilization of irradiation facilities in HANARO, and summarizes ongoing research efforts to deploy advanced irradiation technology.

  10. In vitro synthesis and purification of PhIP-deoxyguanosine and PhIP-DNA oligomer covalent complexes

    Energy Technology Data Exchange (ETDEWEB)

    Freeman, J.

    1994-12-01

    2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) is a heterocyclic amine compound formed when meats are cooked at high temperatures. PhIP damages DNA by forming covalent complexes with DNA carcinogen. In an effort to understand how the binding of PhIP to DNA may cause cancer, it is important to characterize the structures of PhIP-damaged DNA molecules. Our HPLC data support fluorescence and {sup 32}P Post-labeling studies which indicate the formation of several species of 2{prime}deoxyguanosine-(dG) or oligodeoxynucleotide-PhIP adducts. The reaction of PhIP with dG resulted in a reddish precipitate that was likely the major adduct, N-(deoxyguanosin-8-yl)-PhIP (dG-C8-PhIP) adduct, with a more polar adduct fraction remaining in the supernatant. Reversed-phase HPLC analysis of the adducts in the supernatant revealed the existence of species of much shorter retention times than the dG-C8-PhIP adduct, confirming that these species are more polar than dG-C8-PhIP. At least four adducts were formed in the reaction of PhIP with DNA oligomer. HPLC analysis of the PhIP-DNA oligomer supernatant after butanol extractions revealed four unresolved peaks which spectra had maximum wavelengths between 340 and 360 nm. Though adduct peaks were not completely resolved, there was {approximately}3 minutes interval between the DNA oligomer peak and the adduct peaks. Furthermore, fluorescence emission data of the DNA oligomer-PhIP adduct solution show heterogeneous binding. The more polar PhIP adducts were fraction-collected and their structures will be solved by nuclear magnetic resonance or x-ray crystallography.

  11. Glucose-lowering effect of BTS 67 582.

    Science.gov (United States)

    Page, T; Bailey, C J

    1997-12-01

    1. The hypoglycaemic effect of BTS 67 582 (1,1-dimethyl-2(2-morpholinophenyl) guanidine fumarate) was studied in normal rats. 2. BTS 67 582 (100 mg kg(-1), p.o.) acutely lowered basal plasma glucose concentrations: onset within 1 h, maximum decrease of >40% at 2-3 h, and partial return to euglycaemia by 5 h. Plasma insulin concentrations were increased: onset within 30 min, maximum increase 3 fold at 1-2 h; returning to normal by 5 h. 3. BTS 67 582 (100 mg kg(-1)) increased (by 56%) the rate of disappearance of plasma glucose during an intravenous glucose tolerance test, accompanied by a 51% increase in insulin concentrations. 4. During hyperglycaemic clamp studies BTS 67 582 (100 mg kg(-1)) increased glucose utilization 3 fold. This was associated with a 3 fold increase in insulin concentrations, even in the presence of adrenaline at a dosage which inhibits glucose-induced insulin release. 5. When the insulin-releasing effect of BTS 67 582 (100 mg kg(-1)) was inhibited by infusion of somatostatin, there was no effect on glycaemia. 6. Insulin-dependent diabetic BB/S rats, which do not produce endogenous insulin, showed no effect of BTS 67 582 (100 mg kg(-1)) on plasma glucose concentrations in the presence or absence of exogenous insulin. 7. The results demonstrate an acute hypoglycaemic effect of BTS 67 582 which appears to result mainly from its potent insulin-releasing action.

  12. Mutagenicity of γ-irradiated oxygenated and deoxygenated solutions of 2-deoxy-D-ribose and D-ribose in Salmonella typhimurium

    International Nuclear Information System (INIS)

    Wilmer, J.; Leveling, H.; Schubert, J.

    1981-01-01

    Solutions of 2-deoxy-D-ribose and D-ribose were γ-irradiated under different experimental conditions and tested for mutagenicity, with and without preincubation, in Salmonella typhimurium. The irradiated sugar solutions were mutagenic in the tester strains TA 100 and TA 98. Except for malonaldehyde (MDA), which is not mutagenic in the concentrations produced radiolytically, the relative mutagenicities of the individual radiolytic products are unknown. With irradiated solutions of 2-deoxy-D-ribose, a relationship was found between the level of non-MDA aldehydes and the mutagenicity in TA 100. Heating the irradiated solutions of 2-deoxy-D-ribose resulted in a temperature-dependent reduction fo the mutagenicity. Autoclaved, non-irradiated solutions of 2-deoxy-D-ribose were not mutagenic in the Salmonella test. (orig.)

  13. Capsule Development and Utilization for Material Irradiation Tests

    International Nuclear Information System (INIS)

    Kang, Young Hwan; Kim, B. G.; Joo, K. N.

    2003-05-01

    The objective of this project was to establish basic capsule irradiation technology using the multi-purpose research reactor [HANARO] to eventually support national R and D projects of advanced fuel and materials related to domestic nuclear power plants and next generation reactors. There are several national nuclear projects in KAERI, which require several irradiation tests to investigate in-pile behavior of nuclear reactor fuel and materials for the R and D of several types of fuels such as advanced PWR and DUPIC fuels and for the R and D of structural materials such as RPV(reactor pressure vessel) steel, Inconel, zirconium alloy, and stainless steel. At the moment, internal and external researchers in institutes, industries and universities are interested in investigating the irradiation characteristics of materials using the irradiation facilities of HANARO. For these kinds of material irradiation tests, it is important to develop various capsules using our own techniques. The development of capsules requires several leading-edge technologies and our own experiences related to design and fabrication. In the second phase from April 1,2000 to March 31, 2003, the utilization technologies were developed using various sensors for the measurements of temperature, pressure and displacement, and instrumented capsule technologies for the required fuel irradiation tests were developed. In addition, the improvement of the existing capsule technologies and the development of an in-situ measurable creep capsule for specific purposes were done to meet the various requirements of users

  14. Status of fuel irradiation tests in HANARO

    International Nuclear Information System (INIS)

    Kim, Hark Rho; Lee, Choong Sung; Lee, Kye Hong; Jun, Byung Jin; Lee, Ji Bok

    1999-01-01

    Since 1996 after finishing the long-term operational test, HANARO (High-Flux Advanced Neutron Application Reactor) has been extensively used for material irradiation tests, beam application research, radioisotope production and neutron activation analysis. This paper presents the fuel irradiation test activities which are now conducted or have been finished in HANARO. KAERI developed LEU fuel using an atomization method for the research reactors. Using this LEU, we have set up and conducted three irradiation programs: (1) medium power irradiation test using a short-length mini-assembly made of 3.15 gU/cc U 3 Si, (2) high power irradiation tests using full-length test assemblies made of 3.15 gU/cc U 3 Si, and (3) irradiation test using a short-length mini-plate made of 4.8 gU/cc U 3 Si 2 . DUPIC (Direct Use of spent PWR fuels in CANDU Reactors) simulation fuel pellets, of which compositions are very similar to DUPIC pellets to keep the similarity in the thermo-mechanical property, were developed. Three mini-elements including 5 pellets each were installed in a capsule. This capsule has been irradiated for 2 months and unloaded from the HANARO core at the end of September 1999. Another very important test is the HANARO fuel qualification program at high power, which is required to resolve the licensing issue. This test is imposed on the HANARO operation license due to insufficient test data under high power environment. To resolve this licensing issue, we have been carrying out the required irradiation tests and PIE (Post-irradiation Examination) tests. Through this program, it is believed that the resolution of the licensing issue is achieved. In addition to these programs, several fuel test plans are under way. Through these vigorous activities of fuel irradiation test programs, HANARO is sure to significantly contribute to the national nuclear R and D programs. (author)

  15. 3D-FBK Pixel sensors: recent beam tests results with irradiated devices

    CERN Document Server

    Micelli, A; Sandaker, H; Stugu, B; Barbero, M; Hugging, F; Karagounis, M; Kostyukhin, V; Kruger, H; Tsung, J W; Wermes, N; Capua, M; Fazio, S; Mastroberardino, A; Susinno, G; Gallrapp, C; Di Girolamo, B; Dobos, D; La Rosa, A; Pernegger, H; Roe, S; Slavicek, T; Pospisil, S; Jakobs, K; Kohler, M; Parzefall, U; Darbo, G; Gariano, G; Gemme, C; Rovani, A; Ruscino, E; Butter, C; Bates, R; Oshea, V; Parker, S; Cavalli-Sforza, M; Grinstein, S; Korokolov, I; Pradilla, C; Einsweiler, K; Garcia-Sciveres, M; Borri, M; Da Via, C; Freestone, J; Kolya, S; Lai, C H; Nellist, C; Pater, J; Thompson, R; Watts, S J; Hoeferkamp, M; Seidel, S; Bolle, E; Gjersdal, H; Sjobaek, K N; Stapnes, S; Rohne, O; Su, D; Young, C; Hansson, P; Grenier, P; Hasi, J; Kenney, C; Kocian, M; Jackson, P; Silverstein, D; Davetak, H; DeWilde, B; Tsybychev, D; Dalla Betta, G F; Gabos, P; Povoli, M; Cobal, M; Giordani, M P; Selmi, L; Cristofoli, A; Esseni, D; Palestri, P; Fleta, C; Lozano, M; Pellegrini, G; Boscardin, M; Bagolini, A; Piemonte, C; Ronchin, S; Zorzi, N; Hansen, T E; Hansen, T; Kok, A; Lietaer, N; Kalliopuska, J; Oja, A

    2011-01-01

    The Pixel detector is the innermost part of the ATLAS experiment tracking device at the Large Hadron Collider (LHC), and plays a key role in the reconstruction of the primary and secondary vertices of short-lived particles. To cope with the high level of radiation produced during the collider operation, it is planned to add to the present three layers of silicon pixel sensors which constitute the Pixel Detector, an additional layer (Insertable B-Layer, or IBL) of sensors. 3D silicon sensors are one of the technologies which are under study for the IBL. 3D silicon technology is an innovative combination of very-large-scale integration (VLSI) and Micro-Electro-Mechanical-Systems (MEMS) where electrodes are fabricated inside the silicon bulk instead of being implanted on the wafer surfaces. 3D sensors, with electrodes fully or partially penetrating the silicon substrate, are currently fabricated at different processing facilities in Europe and USA. This paper reports on the 2010 June beam test results for irradi...

  16. Irradiation tests report of the 32nd cycle in 'JOYO'

    International Nuclear Information System (INIS)

    1998-09-01

    This report summarizes the operating and irradiation data of the experimental reactor 'JOYO' 32nd cycle, and estimates the 33rd cycle irradiation condition. Irradiation tests in the 31st cycle are as follows: (1) B-type irradiation rig (B9). (a) High burn up performance tests of MONJU' fuel pins, advanced austenitic steel cladding fuel pins, large diameter fuel pins, ferrite steel cladding fuel pins (in collaboration with the USA) and large diameter annular pellet fuel pins. (b) Mixed carbide and nitride fuel pins irradiation tests (in collaboration with JAERI). (2) C-type irradiation rig (C4F). (a) High burn up performance test of advanced austenitic steel cladding fuel pins (in collaboration with France). (3) C-type irradiation rig (C6D). (a) Large diameter fuel pins irradiation test. (4) Absorber Materials Irradiation Rig (AMIR-6). (a) Run to absorber pin's cladding breach. (5) Absorber Materials Irradiation Rig (AMIR-8). (a) High-temperature shroud and Na-bond elements tests. (6) Core Materials Irradiation Rig (CMIR-5-1). (a) Core materials irradiation tests. (7) Structure Materials Irradiation Rigs (SMIR). (a) Material irradiation tests (in collaboration with universities). (b) Surveillance back up tests for MONJU'. (8) MAterial testing RIg with temperature COntrol (MARICO-1). (a) Material irradiation tests (in collaboration with universities), (b) Creep rupture tests of the core materials for the demonstration reactor. (9) Upper core structure irradiation Plug Rig (UPR-1-5). (a) Upper core neutron spectrum effect and accelerated irradiation effect. The maximum burn-up driver assembly 'PFD503' reached 65,600 MWd/t (pin average). (author)

  17. A 39-kD plasma membrane protein (IP39) is an anchor for the unusual membrane skeleton of Euglena gracilis

    International Nuclear Information System (INIS)

    Rosiere, T.K.; Marrs, J.A.; Bouck, G.B.

    1990-01-01

    The major integral plasma membrane protein (IP39) of Euglena gracilis was radiolabeled, peptide mapped, and dissected with proteases to identify cytoplasmic domains that bind and anchor proteins of the cell surface. When plasma membranes were radioiodinated and extracted with octyl glucoside, 98% of the extracted label was found in IP39 or the 68- and 110-kD oligomers of IP39. The octyl glucoside extracts were incubated with unlabeled cell surface proteins immobilized on nitrocellulose (overlays). Radiolabel from the membrane extract bound one (80 kD) of the two (80 and 86 kD) major membrane skeletal protein bands. Resolubilization of the bound label yielded a radiolabeled polypeptide identical in Mr to IP39. Intact plasma membranes were also digested with papain before or after radioiodination, thereby producing a cytoplasmically truncated IP39. The octyl glucoside extract of truncated IP39 no longer bound to the 80-kD membrane skeletal protein in the nitrocellulose overlays. EM of intact or trypsin digested plasma membranes incubated with membrane skeletal proteins under stringent conditions similar to those used in the nitrocellulose overlays revealed a partially reformed membrane skeletal layer. Little evidence of a membrane skeletal layer was found, however, when plasma membranes were predigested with papain before reassociation. A candidate 80-kD binding domain of IP39 has been tentatively identified as a peptide fragment that was present after trypsin digestion of plasma membranes, but was absent after papain digestion in two-dimensional peptide maps of IP39. Together, these data suggest that the unique peripheral membrane skeleton of Euglena binds to the plasma membrane through noncovalent interactions between the major 80-kD membrane skeletal protein and a small, papain sensitive cytoplasmic domain of IP39

  18. Capsule Development and Utilization for Material Irradiation Tests

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Bong Goo; Kang, Y H; Cho, M S [and others

    2007-06-15

    The essential technology for an irradiation test of materials and nuclear fuel has been successively developed and utilized to meet the user's requirements in Phase I(July 21, 1997 to March 31, 2000). It enables irradiation tests to be performed for a non-fissile material under a temperature control(300{+-}10 .deg. C) in a He gas environment, and most of the irradiation tests for the internal and external users are able to be conducted effectively. The basic technology was established to irradiate a nuclear fuel, and a creep capsule was also developed to measure the creep property of a material during an irradiation test in HANARO in Phase II(April 1, 2000 to March 31, 2003). The development of a specific purpose capsule, essential technology for a re-irradiation of a nuclear fuel, advanced technology for an irradiation of materials and a nuclear fuel were performed in Phase III(April 1, 2003 to February 28, 2007). Therefore, the technology for an irradiation test was established to support the irradiation of materials and a nuclear fuel which is required for the National Nuclear R and D Programs. In addition, an improvement of the existing capsule design and fabrication technology, and the development of an instrumented capsule for a nuclear fuel and a specific purpose will be able to satisfy the user's requirements. In order to support the irradiation test of materials and a nuclear fuel for developing the next generation nuclear system, it is also necessary to continuously improve the design and fabrication technology of the existing capsule and the irradiation technology.

  19. Needs of in-situ materials testing under neutron irradiation

    International Nuclear Information System (INIS)

    Noda, K.; Hishinuma, A.; Kiuchi, K.

    1989-01-01

    Under neutron irradiation, the component atoms of materials are displaced as primary knock-on atoms, and the energy of the primary knock-on atoms is consumed by electron excitation and nuclear collision. Elementary irradiation defects accumulate to form damage structure including voids and bubbles. In situ test under neutron irradiation is necessary for investigating into the effect of irradiation on creep behavior, the electric properties of ceramics, transport phenomena and so on. The in situ test is also important to investigate into the phenomena related to the chemical reaction with environment during irradiation. Accelerator type high energy neutron sources are preferable to fission reactors. In this paper, the needs and the research items of in situ test under neutron irradiation using a D-Li stripping type high energy neutron source on metallic and ceramic materials are described. Creep behavior is one of the most important mechanical properties, and depends strongly on irradiation environment, also it is closely related to microstructure. Irradiation affects the electric conductibity of ceramics and also their creep behavior. In this way, in situ test is necessary. (K.I.)

  20. Capsule Development and Utilization for Material Irradiation Tests

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Bong Goo; Kang, Y. H.; Cho, M. S. (and others)

    2007-06-15

    The essential technology for an irradiation test of materials and nuclear fuel has been successively developed and utilized to meet the user's requirements in Phase I(July 21, 1997 to March 31, 2000). It enables irradiation tests to be performed for a non-fissile material under a temperature control(300{+-}10 .deg. C) in a He gas environment, and most of the irradiation tests for the internal and external users are able to be conducted effectively. The basic technology was established to irradiate a nuclear fuel, and a creep capsule was also developed to measure the creep property of a material during an irradiation test in HANARO in Phase II(April 1, 2000 to March 31, 2003). The development of a specific purpose capsule, essential technology for a re-irradiation of a nuclear fuel, advanced technology for an irradiation of materials and a nuclear fuel were performed in Phase III(April 1, 2003 to February 28, 2007). Therefore, the technology for an irradiation test was established to support the irradiation of materials and a nuclear fuel which is required for the National Nuclear R and D Programs. In addition, an improvement of the existing capsule design and fabrication technology, and the development of an instrumented capsule for a nuclear fuel and a specific purpose will be able to satisfy the user's requirements. In order to support the irradiation test of materials and a nuclear fuel for developing the next generation nuclear system, it is also necessary to continuously improve the design and fabrication technology of the existing capsule and the irradiation technology.

  1. 21 CFR 582.5890 - Tocopherols.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Tocopherols. 582.5890 Section 582.5890 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS... 1 § 582.5890 Tocopherols. (a) Product. Tocopherols. (b) Conditions of use. This substance is...

  2. 21 CFR 582.5695 - Riboflavin.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Riboflavin. 582.5695 Section 582.5695 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS... 1 § 582.5695 Riboflavin. (a) Product. Riboflavin. (b) Conditions of use. This substance is generally...

  3. 21 CFR 582.5835 - Sorbitol.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Sorbitol. 582.5835 Section 582.5835 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS, FEEDS... § 582.5835 Sorbitol. (a) Product. Sorbitol. (b) Conditions of use. This substance is generally...

  4. Development of a type IP-2 freight container and leak testing during the longitudinal and transverse racking tests

    International Nuclear Information System (INIS)

    Holden, G.V.

    2002-01-01

    The leak performance of freight containers has never been particularly well defined within the UK and up to the publication of 'A DETR guide to the approval of freight containers as IP-2 and IP-3 packages' freight containers with twin rear doors were acceptable as IP-2/3 packages. The containment argument has usually been based on providing adequate load securing and transport under exclusive use (with no transhipment between modes). Hence the likelihood for dropping the freight container during transhipment is eliminated. These arguments are less acceptable to competent authorities and the document above requires that leak integrity is determined during the standard freight container tests. This paper outlines the methodology used to determine the acceptable leak rate from the container (in terms of a pressure drop); the justification for conducting leak testing during racking only; the results of tests and difficulties that were overcome during design. (author)

  5. 21 CFR 582.5159 - Biotin.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Biotin. 582.5159 Section 582.5159 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS, FEEDS... § 582.5159 Biotin. (a) Product. Biotin. (b) Conditions of use. This substance is generally recognized as...

  6. 21 CFR 582.5118 - Alanine.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Alanine. 582.5118 Section 582.5118 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS, FEEDS... § 582.5118 Alanine. (a) Product. Alanine (L- and DL-forms). (b) Conditions of use. This substance is...

  7. 21 CFR 582.5920 - Tyrosine.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Tyrosine. 582.5920 Section 582.5920 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS, FEEDS... § 582.5920 Tyrosine. (a) Product. Tyrosine (L- and DL-forms). (b) Conditions of use. This substance is...

  8. Irradiation for sprouting inhibition of Kponan yams in Cote d'Ivoire

    International Nuclear Information System (INIS)

    Kodia, A.A.

    2002-01-01

    Yams of the Kponan variety were transported from Abidjan, Cote d'Ivoire, to Accra, Ghana, irradiated at the facility operated by the Ghana Atomic Energy Commission and brought back to Abidjan, Cote d'Ivoire. The law no 98-593 on radiation protection and nuclear safety was promulgated on 10 November 1998. In its article 8 it is said that food and industrial products irradiation facilities shall comply with the requirements of the International Code of Practice. The regulations on food irradiation based on this main law are now being considered for promulgation. The lack of regulations makes it difficult to legally conduct test marketing of irradiated yams. The economic feasibility of irradiating yams in Ghana and selling them in Cote d'Ivoire has been investigated. (author)

  9. MAFF sponsored research: detection tests for irradiated food

    International Nuclear Information System (INIS)

    Blackburn, C.M.; Holley, P.A.; Pryke, D.C.

    1993-01-01

    In their 1986 report on the safety and wholesomeness of irradiated food the UK Advisory Committee on Irradiated and Novel Foods (ACINF) recognised that a generally applicable test to determine if a food had been irradiated was not available. The committee considered that, although not a pre-requisite, the existence of a detection test would be a useful supplement to a control system and do much to reassure consumers; with this in mind ACINF recommended that detection methods should be kept under review. As a consequence, in 1987 the Ministry initiated a comprehensive R and D detection test programme. Over fifty papers have been published to date as a result of this programme. MAFF (Ministry Of Agriculture Fisheries and Food) has also been involved in other research associated with irradiation and food safety, some of which is described in this paper. This paper aims to give an overview of recent work funded under the food irradiation programme. Twelve projects have been supported over the last two years, ten of which involved the development of detection tests for irradiated food. A summary of these projects is presented: - Thermoluminescence; - Electron Spin Resonance; - 2-alkylcyclobutanones; -Determination Of Hydrogen; - Differential Scanning Calorimetry; - Limulus Amoebocyte Lysate; - DNA; - Pesticide Breakdown; - Neutron Irradiation; -Future Plans. (orig./vhe)

  10. Fabrication of irradiation capsule for IASCC irradiation tests (2). Irradiation capsule for crack propagation test (Joint research)

    International Nuclear Information System (INIS)

    Ide, Hiroshi; Matsui, Yoshinori; Kawamata, Kazuo; Taguchi, Taketoshi; Kanazawa, Yoshiharu; Onuma, Yuichi; Watanabe, Hiroyuki; Inoue, Shuichi; Izumo, Hironobu; Ishida, Takuya; Saito, Takashi; Ishitsuka, Etsuo; Kawamura, Hiroshi; Kaji, Yoshiyuki; Ugachi, Hirokazu; Tsukada, Takashi

    2008-03-01

    It is known that irradiation Assisted Stress Corrosion Cracking (IASCC) occurs when austenitic stainless steel components used for light water reactor (LWR) are irradiated for a long period. In order to evaluate the high aging of the nuclear power plant, the study of IASCC becomes the important problem. The specimens irradiated in the reactor were evaluated by post irradiation examination in the past study. For the appropriate evaluation of IASCC, it is necessary to test it under the simulated LWR conditions; temperature, water chemistry and irradiation conditions. In order to perform in-pile SCC test, saturated temperature capsule (SATCAP) was developed. There are crack growth test, crack propagation test and so on for in-pile SCC test. In this report, SATCAP for crack propagation test is reported. (author)

  11. Fabrication of irradiation capsule for IASCC irradiation tests (1). Irradiation capsule for crack growth test (Joint research)

    International Nuclear Information System (INIS)

    Ide, Hiroshi; Matsui, Yoshinori; Kawamata, Kazuo; Taguchi, Taketoshi; Kanazawa, Yoshiharu; Onuma, Yuichi; Watanabe, Hiroyuki; Inoue, Shuichi; Izumo, Hironobu; Ishida, Takuya; Saito, Takashi; Ishitsuka, Etsuo; Kawamura, Hiroshi; Kaji, Yoshiyuki; Ugachi, Hirokazu; Tsukada, Takashi

    2008-03-01

    It is known that Irradiation Assisted Stress Corrosion Cracking (IASCC) occurs when austenitic stainless steel components used for light water reactor (LWR) are irradiated for a long period. In order to evaluate the high aging of the nuclear power plant, the study of IASCC becomes the important problem. The specimens irradiated in the reactor were evaluated by post irradiation examination in the past study. For the appropriate evaluation of IASCC, it is necessary to test it under the simulated LWR conditions; temperature, water chemistry and irradiation conditions. In order to perform in-pile SCC test, saturated temperature capsule (SATCAP) was developed. There are crack growth test, crack propagation test and so on for in-pile SCC test. In this report, SATCAP for crack growth test is reported. (author)

  12. Integrity Assessment of HANARO Irradiation Capsule for Long-Term Irradiation Testing

    Energy Technology Data Exchange (ETDEWEB)

    Choo, Kee Nam; Cho, Man Soon; Yang, Sung Woo; Shin, Yoon Taek; Park, Seng Jae; Yang, Tae Ho; Jun, Byung Hyuk; Kim, Myong Seop [KAERI, Daejeon (Korea, Republic of); Hong, Sang Hyun [Chungnam University, Daejeon (Korea, Republic of)

    2016-05-15

    The capsule technology was basically developed for irradiation testing under a commercial reactor operation environment. Most irradiation testing using capsules has been performed at around 300 .deg. C within four reactor operation cycles (about 100 days equivalent to 1.5 dpa (displacement for atom)) at HANARO. Based on the accumulated experience as well as the sophisticated requirements of users, HANARO has recently been required to support national R and D projects requiring much higher neutron fluence. To scope the user requirements for higher neutron irradiation fluence, several efforts using an instrumented capsule have been applied at HANARO. In this paper, the applied stresses on the capsule are estimated because the capsule was suspected to be susceptible to fatigue failure during irradiation testing. In addition, the on-going design improvements of the irradiation capsule for higher neutron irradiation fluence at HANARO are described. The applied stresses on the rod tip were analyzed using the ANSYS program. The applied stresses on the rod tip can be classified into stresses by the designed bottom spring, by the upward flowing coolant, by the capsule vibration, and by the welding residual stress. The maximal stresses due to the first three factors were estimated as 5.4 MPa, 132.9 MPa, and 161 MPa, respectively. These stresses do not exceed the known fatigue strength of stainless steels (∼300 MPa). Residual stress by welding is another possible stress and it is known to occur at up to about 300 MPa.

  13. Post irradiation fracture properties of precipitation-strengthened alloy D21

    International Nuclear Information System (INIS)

    Huang, F.H.

    1986-03-01

    The precipitation strengthened alloys have the potential for use in fuel cladding and duct applications for liquid metal reactors due to their high strength and low swelling rate. Unfortunately, these high strength alloys tend to exhibit poor fracture toughness, and the effects of neutron irradiation on the fracture properties of the material are of concern. Compact tension specimens of alloy D21 were irradiated in the Experimental Breeder Reactor II to a fluence of 2.7 x 10 22 n/cm 2 (E > 0.1 MeV) at 425, 500, 550 and 600 0 C. Fracture toughness tests on these specimens wre performed using electric potential techniques at temperatures ranging from 205 to 425 C. The material exhibited low postirradiation fracture toughness which increased with either increasing test or irradiation temperature. The tearing modulus, however, increased with increasing irradiation temperature but decreased with increasing test temperature. Results wre analyzed using the J-integral approach. The fracture toughness of irradiated D21 was evaluated essentially following the procedure recommended in ASTM Test Method E813. It was found that the data elimination limits illustrated in E813 were too large for the specimens tested, although the thickness criterion was satisfied. The precautions needed to determine J/sub 1c/ based on a reduced data qualification range were disussed

  14. VoIP Accessibility: A Usability Study of Voice over Internet Protocol (VoIP) Systems and A Survey of VoIP Users with Vision Loss

    Science.gov (United States)

    Packer, Jaclyn; Reuschel, William

    2018-01-01

    Introduction: Accessibility of Voice over Internet Protocol (VoIP) systems was tested with a hands-on usability study and an online survey of VoIP users who are visually impaired. The survey examined the importance of common VoIP features, and both methods assessed difficulty in using those features. Methods: The usability test included four paid…

  15. Gamma radiation induced oxidative stress and apoptosis inhibiting properties of bacterial secondary metabolite RK-IP-006.G in J774A.1 murine cell line

    International Nuclear Information System (INIS)

    Malhotra, Poonam; Gupta, Ashutosh K.; Singh, Praveen K.; Chhachhia, Neha; Singh, Shravan K.; Raj Kumar

    2014-01-01

    Redox imbalance due to radiation induced oxidation of vital bio-macromolecules activates inflammatory response cascade leading to cell death. In present study, bacterial secondary metabolite, RK-IP-006.G, was evaluated for its oxidative stress and apoptosis inhibiting activities in irradiated J774A.1 murine macrophage cell line. Radiation induced intracellular ROS generation and its inhibition upon RK-IP-006.G pretreatment was estimated using 2',7'dichlorodihydroflurescein diacetate (DCFDA). Modulation in mitochondrial membrane potential (MMP) in irradiated cells and its protection by RK-IP-006.G pretreatment was evaluated using Rhodamine-123. Modulation in protein expression in irradiated and RK-IP-006.G treated J774A.1 cells was assessed by SDS-PAGE. Compensatory effect of RK-IP-006.G treatment on TNF-α expression in irradiated cells was estimated using ELISA assay. APO-BrDU assay was performed to evaluate radiation-induced apoptosis in irradiated cells. Radiation-induced cell damage and protective ability of RK-IP-006.G was also evaluated using Differential Interference Contrast Microscopy. Results of the study indicated significant (p< 0.05) decrease in DCFDA fluorescence in irradiated cells that were pretreated (∼2h) with RK-IP-006.G (0.25 μg/ml) as compared to irradiated cells. Similarly, significant (p<0.05) decrease in MMP was observed in irradiated cells pretreated with RK-IP-006.G (0.25 μg/ml) as compared to only irradiated cells at 1 h time point. SDS-PAGE analysis clearly demonstrated up-regulation of some prominent proteins in irradiated cells pretreated with RK-IP-006.G at 2-4h after treatment as compared to irradiated control. Significant (p<0.05) down regulation in TNF-α expression was observed in irradiated cells that pretreated with RK-IP-006.G compared to irradiated controls. APO-BrDU assay revealed significant reduction in apoptosis in irradiated cells pretreated with RK-IP-006.G when compared to irradiated control. The findings

  16. Cross-sections and the analysing power of the production reaction p+p→π++d between 516 and 582 MeV

    International Nuclear Information System (INIS)

    Chatelain, P.; Favier, B.; Foroughi, F.; Piffaretti, J.; Nussbaum, C.; Hoftiezer, J.; Weddigen, C.; Jaccard, S.

    1982-01-01

    The differential cross section of the reaction p+p→π + +d at 7 energies from 516 to 582 MeV has been measured. The incident protons were from the PM1 line at SIN. The π and d were detected in coincidence by scintillation counters. The measurement was monitored by the elastic diffusion pp, giving an absolute precision of 1.5% for the cross section. Graphs of results are presented. (G.F.F.)

  17. Radioprotection offered by bacterial secondary metabolite RK-IP-006.G to the mice by oral route of administration

    International Nuclear Information System (INIS)

    Gupta, Ashutosh K.; Malhotra, Poonam; Singh, Praveen K.; Chhachhia, Neha; Singh, Shravan K.; Kumar, Raj

    2014-01-01

    Ionizing radiation is known to cause oxidative damage in biological system primarily by generating reactive oxygen species (ROS). Gastrointestinal system is considered one of the most radiosensitive biological systems. The most radiosensitive cells type found in the intestine are continuously proliferative crypt cells. Damage to intestinal crypt cells lead to gastrointestinal functions impairment that contribute to mortality. In the present study, whole body radioprotective efficacy of bacterial secondary metabolite RK-IP-006.G was evaluated in C57BL/6 male mice. To determine free radical scavenging properties of RK-IP-006.G 2',7'-dichlorodihydrofluorescein diacetate (DCFDA) assay was performed. Radiation induced lipid peroxidation and its inhibition by RK-IP-006.G pretreatment was assessed in intestinal tissue homogenate. To find out cellular antioxidant status of the irradiated and RK-IP- 006.G treated mice, SOD, Catalase, and Glutathion-S-Transferase activity were estimated in intestinal tissue homogenate. Anti-apoptotic and mitochondrial membrane hypopolarization effect of the RK-IP-006.G was also analyzed using fluorescent probes Acridine Orange and Rhodamine123 respectively. Results of the study demonstrated that, RK-IP-006.G pretreatment (∼2h; 150 mg/kg.b.wt. oral administration) to the lethally irradiated (9 Gy) C57BL/6 male mice contributes to >83% whole body radioprotection in mice. Significant (P>0.05%) inhibition in lipid peroxidation was observed in intestinal tissue of irradiated mice pretreated with RK-IP-006.G compared to only irradiated controls. Significant (P>0.05%) increase in antioxidant enzyme i.e. Catalase, SOD and GST activities was reported in irradiated mice pretreated with RK-IP-006.G compared to irradiated control groups. RK-IP-006.G pretreatment also found to be instrumental in inhibiting radiation induced apoptosis and mitochondrial membrane hyperpolarization. In conclusion, present study revealed that bacterial secondary

  18. 21 CFR 582.1631 - Potassium hydroxide.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Potassium hydroxide. 582.1631 Section 582.1631 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL... Additives § 582.1631 Potassium hydroxide. (a) Product. Potassium hydroxide. (b) Conditions of use. This...

  19. Outbreak of Ips nitidus and Ips shangrila in northeastern margin of the Tibetan Plateau

    Czech Academy of Sciences Publication Activity Database

    Jakuš, R.; Kalinová, Blanka; Hoskovec, Michal; Knížek, M.; Schlyter, F.; Sun, J.-H.; Zhang, Q. H.

    2011-01-01

    Roč. 89, - (2011), s. 111-117 ISSN 1436-1566 R&D Projects: GA MŠk ME 860 Institutional research plan: CEZ:AV0Z40550506 Keywords : Ips shangrila * Ips nitidus * pheromone s * GCxGC-TOFMS Subject RIV: CC - Organic Chemistry

  20. Preliminary irradiation test results from the Yankee Atomic Electric Company reactor vessel test irradiation program

    International Nuclear Information System (INIS)

    Biemiller, E.C.; Fyfitch, S.; Campbell, C.A.

    1993-01-01

    The Yankee Atomic Electric Company test irradiation program was implemented to characterize the irradiation response of representative Yankee Rowe reactor vessel beltline plate materials and to remove uncertainties in the analysis of existing irradiation data on the Yankee Rowe reactor vessel steel. Plate materials each containing 0.24 w/o copper, but different nickel contents at 0.63 w/o and 0.19 w/o, were heat treated to simulate the Yankee vessel heat treatment (austenitized at 1800 deg F) and to simulate Regulatory Guide 1.99 database materials (austenitized at 1600 deg. F). These heat treatments produced different microstructures so the effect of microstructure on irradiation damage sensitivity could be tested. Because the nickel content of the test plates varied and the copper level was constant, the effect of nickel on irradiation embrittlement was also tested. Correlation monitor material, HSST-02, was included in the program to benchmark the Ford Nuclear Reactor (U. of Michigan Test Reactor) which had never been used for this type of irradiation program. Materials taken from plate surface locations (vs. 1/4T) were included to test whether or not the improved toughness properties of the plate surface layer, resulting from the rapid quench, is maintained after irradiation. If the improved properties are maintained, pressurized thermal shock calculations could utilize this margin. Finally, for one experiment, irradiations were conducted at two irradiation temperatures (500 deg. F and 550 deg. F) to determine the effect of irradiation temperature on embrittlement. The preliminary results of the irradiation program show an increase in T 30 shift of 69 deg. F for a decrease in irradiation temperature of 50 deg. F. The results suggest that for nickel bearing steels, the superior toughness of plate surface material is maintained after irradiation and for the copper content tested, nickel had no apparent effect on irradiation response. No apparent microstructure

  1. 21 CFR 582.1748 - Sodium caseinate.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Sodium caseinate. 582.1748 Section 582.1748 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL... Additives § 582.1748 Sodium caseinate. (a) Product. Sodium caseinate. (b) Conditions of use. This substance...

  2. 21 CFR 582.5431 - Magnesium oxide.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Magnesium oxide. 582.5431 Section 582.5431 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL... Supplements 1 § 582.5431 Magnesium oxide. (a) Product. Magnesium oxide. (b) Conditions of use. This substance...

  3. 21 CFR 582.1431 - Magnesium oxide.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Magnesium oxide. 582.1431 Section 582.1431 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL... Additives § 582.1431 Magnesium oxide. (a) Product. Magnesium oxide. (b) Conditions of use. This substance is...

  4. 21 CFR 582.5443 - Magnesium sulfate.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Magnesium sulfate. 582.5443 Section 582.5443 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL... Supplements 1 § 582.5443 Magnesium sulfate. (a) Product. Magnesium sulfate. (b) Conditions of use. This...

  5. 21 CFR 582.5230 - Calcium sulfate.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Calcium sulfate. 582.5230 Section 582.5230 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL... Supplements 1 § 582.5230 Calcium sulfate. (a) Product. Calcium sulfate. (b) Conditions of use. This substance...

  6. 21 CFR 582.5195 - Calcium citrate.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Calcium citrate. 582.5195 Section 582.5195 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL... Supplements 1 § 582.5195 Calcium citrate. (a) Product. Calcium citrate. (b) Conditions of use. This substance...

  7. 21 CFR 582.1207 - Calcium lactate.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Calcium lactate. 582.1207 Section 582.1207 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL... Additives § 582.1207 Calcium lactate. (a) Product. Calcium lactate. (b) Conditions of use. This substance is...

  8. 21 CFR 582.1195 - Calcium citrate.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Calcium citrate. 582.1195 Section 582.1195 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL... Additives § 582.1195 Calcium citrate. (a) Product. Calcium citrate. (b) Conditions of use. This substance is...

  9. 21 CFR 582.5446 - Manganese chloride.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Manganese chloride. 582.5446 Section 582.5446 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL... Supplements 1 § 582.5446 Manganese chloride. (a) Product. Manganese chloride. (b) Conditions of use. This...

  10. 21 CFR 582.5252 - Choline chloride.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Choline chloride. 582.5252 Section 582.5252 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL... Supplements 1 § 582.5252 Choline chloride. (a) Product. Choline chloride. (b) Conditions of use. This...

  11. 21 CFR 582.5622 - Potassium chloride.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Potassium chloride. 582.5622 Section 582.5622 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL... Supplements 1 § 582.5622 Potassium chloride. (a) Product. Potassium chloride. (b) Conditions of use. This...

  12. 21 CFR 582.1193 - Calcium chloride.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Calcium chloride. 582.1193 Section 582.1193 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL... Additives § 582.1193 Calcium chloride. (a) Product. Calcium chloride. (b) Conditions of use. This substance...

  13. 21 CFR 582.1742 - Sodium carbonate.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Sodium carbonate. 582.1742 Section 582.1742 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL... Additives § 582.1742 Sodium carbonate. (a) Product. Sodium carbonate. (b) Conditions of use. This substance...

  14. 21 CFR 582.1125 - Aluminum sulfate.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Aluminum sulfate. 582.1125 Section 582.1125 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL... Additives § 582.1125 Aluminum sulfate. (a) Product. Aluminum sulfate. (b) Conditions of use. This substance...

  15. 21 CFR 582.1073 - Phosphoric acid.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Phosphoric acid. 582.1073 Section 582.1073 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL... Additives § 582.1073 Phosphoric acid. (a) Product. Phosphoric acid. (b) Conditions of use. This substance is...

  16. Endurance test of DUPIC irradiation test rig-003

    Energy Technology Data Exchange (ETDEWEB)

    Moon, J.S; Yang, M.S.; Lee, C.Y.; Ryu, J.S.; Jeon, H.G

    2001-04-01

    This report presents the pressure drop, vibration and endurance test results for DUPIC Irradiation Test Rig-003 which was design and fabricated by KAERI. From the pressure drop and vibration test results, it is verified that DUPIC Irradiation Test Rig-003 satisfied the limit conditions of HANARO. And, remarkable wear is not observed in DUPIC Irradiation Test Rig-003 during 40 endurance test days.

  17. 21 CFR 582.5210 - Calcium oxide.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Calcium oxide. 582.5210 Section 582.5210 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS... 1 § 582.5210 Calcium oxide. (a) Product. Calcium oxide. (b) Conditions of use. This substance is...

  18. 21 CFR 582.5930 - Vitamin A.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Vitamin A. 582.5930 Section 582.5930 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS... 1 § 582.5930 Vitamin A. (a) Product. Vitamin A. (b) Conditions of use. This substance is generally...

  19. 21 CFR 582.5985 - Zinc chloride.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Zinc chloride. 582.5985 Section 582.5985 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS... 1 § 582.5985 Zinc chloride. (a) Product. Zinc chloride. (b) Conditions of use. This substance is...

  20. 21 CFR 582.5017 - Aspartic acid.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Aspartic acid. 582.5017 Section 582.5017 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS... 1 § 582.5017 Aspartic acid. (a) Product. Aspartic acid (L- and DL-forms). (b) Conditions of use...

  1. Effect of melatonin and time of administration on irradiation-induced damage to rat testes

    Directory of Open Access Journals (Sweden)

    G. Take

    2009-07-01

    Full Text Available The effect of ionizing irradiation on testes and the protective effects of melatonin were investigated by immunohistochemical and electron microscopic methods. Eighty-two adult male Wistar rats were divided into 10 groups. The rats in the irradiated groups were exposed to a sublethal irradiation dose of 8 Gy, either to the total body or abdominopelvic region using a 60Co source at a focus of 80 cm away from the skin in the morning or evening together with vehicle (20% ethanol or melatonin administered 24 h before (10 mg/kg, immediately before (20 mg/kg and 24 h after irradiation (10 mg/kg, all ip. Caspace-3 immunoreactivity was increased in the irradiated group compared to control (P < 0.05. Melatonin-treated groups showed less apoptosis as indicated by a considerable decrease in caspace-3 immunoreactivity (P < 0.05. Electron microscopic examination showed that all spermatogenic cells, especially primary spermatocytes, displayed prominent degeneration in the groups submitted to total body and abdominopelvic irradiation. However, melatonin administration considerably inhibited these degenerative changes, especially in rats who received abdominopelvic irradiation. Total body and abdominopelvic irradiation induced identical apoptosis and testicular damage. Chronobiological assessment revealed that biologic rhythm does not alter the inductive effect of irradiation. These data indicate that melatonin protects against total body and abdominopelvic irradiation. Melatonin was more effective in the evening abdominopelvic irradiation and melatonin-treated group than in the total body irradiation and melatonin-treated group.

  2. 21 CFR 582.1135 - Ammonium bicarbonate.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Ammonium bicarbonate. 582.1135 Section 582.1135 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS, FEEDS, AND RELATED PRODUCTS SUBSTANCES GENERALLY RECOGNIZED AS SAFE General Purpose Food Additives § 582.1135 Ammonium bicarbonate. (a)...

  3. 21 CFR 582.1613 - Potassium bicarbonate.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Potassium bicarbonate. 582.1613 Section 582.1613 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS, FEEDS, AND RELATED PRODUCTS SUBSTANCES GENERALLY RECOGNIZED AS SAFE General Purpose Food Additives § 582.1613 Potassium bicarbonate. (a)...

  4. 21 CFR 582.6033 - Citric acid.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Citric acid. 582.6033 Section 582.6033 Food and..., FEEDS, AND RELATED PRODUCTS SUBSTANCES GENERALLY RECOGNIZED AS SAFE Sequestrants 2 § 582.6033 Citric acid. (a) Product. Citric acid. 2 For the purpose of this subpart, no attempt has been made to...

  5. 21 CFR 582.5013 - Ascorbic acid.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Ascorbic acid. 582.5013 Section 582.5013 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS... 1 § 582.5013 Ascorbic acid. (a) Product. Ascorbic acid. 1 Amino acids listed in this subpart may be...

  6. 21 CFR 582.1736 - Sodium bicarbonate.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Sodium bicarbonate. 582.1736 Section 582.1736 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS, FEEDS, AND RELATED PRODUCTS SUBSTANCES GENERALLY RECOGNIZED AS SAFE General Purpose Food Additives § 582.1736 Sodium bicarbonate. (a) Product....

  7. MYRRHA, A Flexible Fast Spectrum Irradiation Facility. Current Status of Design

    International Nuclear Information System (INIS)

    Baeten, Peter; Fernandez, Rafaël; De Bruyn, Didier; Van den Eynde, Gert; Leysen, Paul; Aït Abderrahim, Hamid; Castelliti, Diego

    2011-01-01

    R and D program in support of MYRRHA: • Several R&D required for MYRRHA components: - LBE corrosion; - O 2 control in LBE; - Irradiated material properties. • Experimental facilities foreseen in the near future in support of MYRRHA at SCK•CEN premacies: - E-SCAPE: Thermal-hydraulic pool facility with 1:6 scale ratio with MYRRHA; - Liliputter: Pump test loop; - COMPLOT: Isothermal hydraulic loop representing one fuel channel/IPS at full high; - PHX mock-up testing concept, fouling, flow-induced vibrations, (SGTR)…; • Experimental facilities foreseen in the near future in support of MYRRHA at SCK•CEN premacies (continued): - Safety/control rod; - Fuel bundle; - Target window; - Component test pool; - Fuel loader; - Robotic arm; • All experiments planned to be finished before 2016

  8. Protective effect of S-2-(3-aminopropylamino)ethylphosphorothioic acid (WR-2721) on irradiation-induced inhibition of intestinal transport function

    International Nuclear Information System (INIS)

    Chen, T.S.; Ando, M.

    1983-01-01

    The purpose of this study was to investigate the protective effect of S-2-(3-aminopropylamino)ethylphosphorothioic acid (WR-2721) on whole-body irradiation-induced inhibition of intestinal transport function. The jejunal transport of fluid and sugars was studied in male Swiss-Webster mice before and 3 days after whole-body irradiation (1000 rads). The rates of glucose and water transport were decreased by 86 and 70%, respectively, in irradiated animals. However, the rate of transport of 3-O-methyl-D-glucose (3MG) was not affected. In mice receiving WR-2721 (500 mg/kg, ip) 15 to 30 min prior to whole-body irradiation, net water flux was unaffected and the rate of D-glucose transport was decreased only 8%. WR-2721 administered alone (500 mg/kg, ip) had no effect on either D-glucose transport or net water flux across the jejunal mucosa. The results suggest that WR-2721 protects against irradiation-induced inhibition of some intestinal transport functions

  9. Telefonía IP (ToIP): principios fundamentales, arquitectura y aspecto regulatorio en el Ecuador

    OpenAIRE

    Narváez García, William Fernando; Ugalde Peña, Pablo Esteban

    2006-01-01

    En este documento, hemos tratado de explicar el funcionamiento de la telefonía IP dentro de poco, comenzamos hablando con una introducción al tema al comentar sobre la actual tendencia a la conocida como patrón ALL-IP. Luego hemos visto conveniente hacer un comentario acerca de la evolución de las telecomunicaciones desde sus primeros pasos con Guillermo Marconi hasta nuestros días con la ToIP. De modo que existe un concepto claro de lo que la ToIP significa, en primer lugar se explica ...

  10. Design Improvement of Double Pressure Vessel in the In-pile Test Section

    Energy Technology Data Exchange (ETDEWEB)

    Hong, Jintae; Heo, Sung-Ho; Joung, Chang-Young; Kim, Ka-Hye [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2014-10-15

    To carry out an irradiation test of nuclear fuels, a nuclear fuel test rig should be fabricated and installed in the in-pile test section (IPS), which is installed in the reactor hall. While carrying out an irradiation test, sealing out coolant which passes through the test rig is one of the most important issues. In particular, although the double pressure vessel is assembled with the IPS head by two o-rings and six bolts, 15.5 MPa of highly pressurized coolant leaks through the gap between the vessel and IPS head. Because the temperature of the coolant in the test loop is 300 .deg. C , and the pool of HANARO is 40 .deg. C, the double pressure vessel is necessary to insulate them. Therefore, a new design to prevent the leakage of coolant needs to be developed. In this study, EB welding technique is considered to assemble the double pressure vessel and the IPS head, and their mechanical design is modified to enable the welding process. In this study, an improved design for sealing out the coolant at the pressure boundary between the double pressure vessel and the IPS head has been developed. An EB weld is applied to seal out the pressure boundary, and its sealing performance is verified by NDE, a cross section test, and a hydraulic pressure test. From the verification test results, the improved design can be used in fabricating the IPS for a nuclear fuel irradiation test.

  11. Comparison of Integer Programming (IP) Solvers for Automated Test Assembly (ATA). Research Report. ETS RR-15-05

    Science.gov (United States)

    Donoghue, John R.

    2015-01-01

    At the heart of van der Linden's approach to automated test assembly (ATA) is a linear programming/integer programming (LP/IP) problem. A variety of IP solvers are available, ranging in cost from free to hundreds of thousands of dollars. In this paper, I compare several approaches to solving the underlying IP problem. These approaches range from…

  12. Quantification of lacrimal function after D-shaped field irradiation for retinoblastoma

    International Nuclear Information System (INIS)

    Imhof, S.M.; Tan, K.E.W.P.; Hofman, P.

    1993-01-01

    To study the quantitative effects of mega-voltage external beam irradiation in a D-shaped field in patients with retinoblastoma, biomicroscopy was performed in 61 patients and tear function tests (Schirmer-lactoferrin and lysozyme tests) on 45 eyes in 34 irradiated patients. The results were compared with those obtained in 25 non-irradiated control eyes. The Schirmer test was significantly diminished in irradiated eyes, as were the lactoferrin and lysozyme values. A mild to severe keratitis was found in 17 of the 61 patients (28%). A significant correlation (p<0.005) was found between the severe keratitis and the mean Schirmer values; the mean lactoferrin and lysozyme values were diminished in all patients but did not correlate significantly with the corneal abnormalities. These quantitative data, obtained in patients treated for retinoblastoma, affirm the qualitative data found in patients irradiated for other reasons such as orbital or sinus tumours. Irradiation for retinoblastoma is not a harmless treatment and serious late side effects have to be considered. (Author)

  13. HRB-22 capsule irradiation test for HTGR fuel. JAERI/USDOE collaborative irradiation test

    Energy Technology Data Exchange (ETDEWEB)

    Minato, Kazuo; Sawa, Kazuhiro; Fukuda, Kousaku [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment; and others

    1998-03-01

    As a JAERI/USDOE collaborative irradiation test for high-temperature gas-cooled reactor fuel, JAERI fuel compacts were irradiated in the HRB-22 irradiation capsule in the High Flux Isotope Reactor at the Oak Ridge National Laboratory (ORNL). Postirradiation examinations also were performed at ORNL. This report describes 1) the preirradiation characterization of the irradiation samples of annular-shaped fuel compacts containing the Triso-coated fuel particles, 2) the irradiation conditions and fission gas releases during the irradiation to measure the performance of the coated particle fuel, 3) the postirradiation examinations of the disassembled capsule involving visual inspection, metrology, ceramography and gamma-ray spectrometry of the samples, and 4) the accident condition tests on the irradiated fuels at 1600 to 1800degC to obtain information about fuel performance and fission product release behavior under accident conditions. (author)

  14. 40 CFR 52.582 - Control strategy: Ozone.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 3 2010-07-01 2010-07-01 false Control strategy: Ozone. 52.582 Section 52.582 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) APPROVAL AND PROMULGATION OF IMPLEMENTATION PLANS Georgia> § 52.582 Control strategy: Ozone. (a) Approval...

  15. Preliminary irradiation test results from the Yankee Atomic Electric Company reactor vessel test irradiation program

    International Nuclear Information System (INIS)

    Biemiller, E.C.; Fyfitch, Stephen; Campbell, C.A.

    1994-01-01

    The Yankee Atomic Electric Company test irradiation program was implemented to characterize the irradiation response of representative Yankee Rowe reactor vessel beltline plate materials and to remove uncertainties in the analysis of existing irradiation data on the Yankee Rowe reactor vessel steel. Plate materials each containing 0.24 w/o copper, but different nickel contents at 0.63 w/o and 0.19 w/o, were heat treated to simulate the Yankee vessel heat treatment (austenitized at 982 o C (1800 o F)) and to simulate Regulatory Guide 1.99 database materials (austenitized at 871 o C (1600 o F)). These heat treatments produced different microstructures so the effect of microstructure on irradiation damage sensitivity could be tested. Because the nickel content of the test plates varied and the copper level was constant, the effect of nickel on irradiation embrittlement was also tested. Correlation monitor material, HSST-02, was included in the program to benchmark the Ford Nuclear Reactor (University of Michigan Test Reactor) which had never been used before for this type of irradiation program. Materials taken from plate surface locations (versus 1/4 T) were included to test whether or not the improved toughness properties of the plate surface layer, resulting from the rapid quench, are maintained after irradiation. If the improved properties are maintained, pressurized thermal shock calculations could utilize this margin. Finally, for one experiment, irradiations were conducted at two irradiation temperatures (260 o C and 288 o C) to determine the effect of irradiation temperature on embrittlement. (Author)

  16. 21 CFR 582.1781 - Sodium aluminum phosphate.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Sodium aluminum phosphate. 582.1781 Section 582.1781 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED... Additives § 582.1781 Sodium aluminum phosphate. (a) Product. Sodium aluminum phosphate. (b) Conditions of...

  17. Irradiation effects test series test IE-1 test results report

    International Nuclear Information System (INIS)

    Quapp, W.J.; Allison, C.M.; Farrar, L.C.; Mehner, A.S.

    1977-03-01

    The report describes the results of the first programmatic test in the Nuclear Regulatory Commission Irradiation Effects Test Series. This test (IE-1) used four 0.97m long PWR-type fuel rods fabricated from previously irradiated Saxton fuel. The objectives of this test were to evaluate the effect of fuel pellet density on pellet-cladding interaction during a power ramp and to evaluate the influence of the irradiated state of the fuel and cladding on rod behavior during film boiling operation. Data are presented on the behavior of irradiated fuel rods during steady-state operation, a power ramp, and film boiling operation. The effects of as-fabricated gap size, as-fabricated fuel density, rod power, and power ramp rate on pellet-cladding interaction are discussed. Test data are compared with FRAP-T2 computer model predictions, and comments on the consequences of sustained film boiling operation on irradiated fuel rod behavior are provided

  18. An Attacker-Defender Model for IP-Based Networks

    National Research Council Canada - National Science Library

    Barkley, Timothy R

    2008-01-01

    .... Because IP flows are defined essentially in terms of origin-destination (O-D) pairs, we represent IP traffic engineering as a multi-commodity flow problem in which each O-D pair is treated as a separate commodity...

  19. 21 CFR 582.5892 - a-Tocopherol acetate.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false a-Tocopherol acetate. 582.5892 Section 582.5892 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL... Supplements 1 § 582.5892 a-Tocopherol acetate. (a) Product. a-Tocopherol acetate. (b) Conditions of use. This...

  20. 21 CFR 582.5697 - Riboflavin-5-phosphate.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Riboflavin-5-phosphate. 582.5697 Section 582.5697 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL... Supplements 1 § 582.5697 Riboflavin-5-phosphate. (a) Product. Riboflavin-5-phosphate. (b) Conditions of use...

  1. 21 CFR 582.5945 - Vitamin B12.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Vitamin B12. 582.5945 Section 582.5945 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS... 1 § 582.5945 Vitamin B12. (a) Product. Vitamin B12. (b) Conditions of use. This substance is...

  2. 21 CFR 582.3890 - Tocopherols.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Tocopherols. 582.3890 Section 582.3890 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS... Tocopherols. (a) Product. Tocopherols. (b) Conditions of use. This substance is generally recognized as safe...

  3. 21 CFR 582.1400 - Lecithin.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Lecithin. 582.1400 Section 582.1400 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS, FEEDS... Lecithin. (a) Product. Lecithin. (b) Conditions of use. This substance is generally recognized as safe when...

  4. 21 CFR 582.1540 - Nitrogen.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Nitrogen. 582.1540 Section 582.1540 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS, FEEDS... Nitrogen. (a) Product. Nitrogen. (b) Conditions of use. This substance is generally recognized as safe when...

  5. Effects of follicle stimulationg hormone on {gamma}-ray irradiated immature mouse ovarian follicles

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Jin Kyu; Lee, Chang Joo; Lee, Young Keun [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of); Song, Kang Won; Yoon, Yong Dal [Hanyang Univ., Seoul (Korea, Republic of)

    1998-06-01

    To assess the radioprotective effects of Follicle Stimulating Hormone (FSH) on ovarian follicles, 3 week-old female mice were irradiated with 8.33 Gy of {gamma}-ray (group R) and followed by 5 IU ip-injection of FSH (group RF). For control groups, 5 IU of saline (group C) or 5 IU of FSH (group F) was ip-injected. Ovaries were collected 0h, 6h, 12h, 1d, 2d, 4d, and 8d after irradiation or saline/FSH injection, and followed by fixation in neutral buffered formalin for routine histochemistry. Immunohistochemistry was used to assess the status of follicles and DNA fragmentation was analyzed by agarose gel electrophoresis for total DNA. Staining specific for apoptotic follicles showed high intensity at 6h and 12h in group R and RF. On the other hand, staining specific for proliferating follicles showed noticeably high intensity at 8d in group R and RF. DNA fragmentation of 185bp increased with time in all experimental groups. Especially 370bp appeared at 6h in group R, then disappeared after 1d. In case of group RF, it appeared at 12h and disappeared after 1d. From the above results, the irradiated antral follicles become completely disappeared from 4d to 8d, and then new follicles started to grow again at 8d. FSH had delaying or suppressing effects on follicular atresia after irradiation. In addition, it became clear that radiation-induced follicular atresia was mediated by granulosa cell apoptosis.

  6. Design, irradiation, and post-irradiation examination of the UC and (U,Pu)C fuel rods of the test groups Mol-11/K1 and Mol-11/K2

    International Nuclear Information System (INIS)

    Freund, D.; Elbel, H.; Steiner, H.

    1976-06-01

    The test groups K1 and K2 of the irradiation experiment Mol-11 are reported. Design, irradiation, and post-irradiation examination of the fuel rods irradiated are described. Mol-11/K1 consisted of one fuel rod with UC of 94% T.D. and helium bonding. This test group was intended to prove the high power irradiation capsule in pile. Mol-11/K2 consists of three fuel rods in total. One of these is presently still in the reactor. In this test group mixed carbide fuel of 83% T.D. and 15% Pu content under helium bonding is irradiated. The fuel rod K2-2 was provided with a capillary tube for the continuous measurement of fission gas pressure built up. 1.4988 stainless steel was chosen as cladding material. The final burnup lies between 35 and 70 MWd/kg M. Post-irradiation examination of the two test groups covers a theoretical analysis of the irradiation behaviour. (orig./GSCH) [de

  7. 1-800-CALL-H.E.P. -- Experiences on a voice-over-IP test bed

    International Nuclear Information System (INIS)

    Matthews, W.

    2000-01-01

    Highly interactive Internet applications such as Voice-over-IP are extremely sensitive to network performance. Even on high performance research networks, many cases will require the use of differentiated services to achieve high (toll) quality conversations. In this talk the authors will describe a test bed over the Energy Sciences network (ESnet) between Lawrence Berkeley National Laboratory (LBNL), Stanford Linear Accelerator Center (SLAC), Argonne National Laboratory (ANL) and Sandia National Laboratory (Sandia). In particular the characteristics of Voice-over-IP calls between LBNL and SLAC will be reviewed and the effect of low, moderate and high congestion on the link will be quantified. The use of Per Hop Behavior (PHB) in IP headers with Weighted Fair Queuing (WFQ) in routers and the benefit they provide will be explained. A model of flows and performance will be presented and new techniques to predict the quality of calls are under development and will be reviewed. Comparisons with telephone reliability will be discussed and the feasibility of wide spread deployment of VoIP in HEP will be considered

  8. Irradiation strongly reduces tumorigenesis of human induced pluripotent stem cells

    International Nuclear Information System (INIS)

    Inui, Shoki; Minami, Kazumasa; Ito, Emiko; Imaizumi, Hiromasa; Mori, Seiji; Koizumi, Masahiko; Fukushima, Satsuki; Miyagawa, Shigeru; Sawa, Yoshiki; Matsuura, Nariaki

    2017-01-01

    Induced pluripotent stem (iPS) cells have demonstrated they can undergo self-renewal, attain pluripotency, and differentiate into various types of functional cells. In clinical transplantation of iPS cells, however, a major problem is the prevention of tumorigenesis. We speculated that tumor formation could be inhibited by means of irradiation. Since the main purpose of this study was to explore the prevention of tumor formation in human iPS (hiPS) cells, we tested the effects of irradiation on tumor-associated factors such as radiosensitivity, pluripotency and cell death in hiPS cells. The irradiated hiPS cells showed much higher radiosensitivity, because the survival fraction of hiPS cells irradiated with 2 Gy was < 10%, and there was no change of pluripotency. Irradiation with 2 and 4 Gy caused substantial cell death, which was mostly the result of apoptosis. Irradiation with 2 Gy was detrimental enough to cause loss of proliferation capability and trigger substantial cell death in vitro. The hiPS cells irradiated with 2 Gy were injected into NOG mice (NOD/Shi-scid, IL-2 Rγnull) for the analysis of tumor formation. The group of mice into which hiPS cells irradiated with 2 Gy was transplanted showed significant suppression of tumor formation in comparison with that of the group into which non-irradiated hiPS cells were transplanted. It can be presumed that this diminished rate of tumor formation was due to loss of proliferation and cell death caused by irradiation. Our findings suggest that tumor formation following cell therapy or organ transplantation induced by hiPS cells may be prevented by irradiation.

  9. ELRIS2D: A MATLAB Package for the 2D Inversion of DC Resistivity/IP Data

    OpenAIRE

    Akca Irfan

    2016-01-01

    ELRIS2D is an open source code written in MATLAB for the two-dimensional inversion of direct current resistivity (DCR) and time domain induced polarization (IP) data. The user interface of the program is designed for functionality and ease of use. All available settings of the program can be reached from the main window. The subsurface is discretized using a hybrid mesh generated by the combination of structured and unstructured meshes, which reduces the computational cost of the whole invers...

  10. An Iterative Interplanetary Scintillation (IPS) Analysis Using Time-dependent 3-D MHD Models as Kernels

    Science.gov (United States)

    Jackson, B. V.; Yu, H. S.; Hick, P. P.; Buffington, A.; Odstrcil, D.; Kim, T. K.; Pogorelov, N. V.; Tokumaru, M.; Bisi, M. M.; Kim, J.; Yun, J.

    2017-12-01

    The University of California, San Diego has developed an iterative remote-sensing time-dependent three-dimensional (3-D) reconstruction technique which provides volumetric maps of density, velocity, and magnetic field. We have applied this technique in near real time for over 15 years with a kinematic model approximation to fit data from ground-based interplanetary scintillation (IPS) observations. Our modeling concept extends volumetric data from an inner boundary placed above the Alfvén surface out to the inner heliosphere. We now use this technique to drive 3-D MHD models at their inner boundary and generate output 3-D data files that are fit to remotely-sensed observations (in this case IPS observations), and iterated. These analyses are also iteratively fit to in-situ spacecraft measurements near Earth. To facilitate this process, we have developed a traceback from input 3-D MHD volumes to yield an updated boundary in density, temperature, and velocity, which also includes magnetic-field components. Here we will show examples of this analysis using the ENLIL 3D-MHD and the University of Alabama Multi-Scale Fluid-Kinetic Simulation Suite (MS-FLUKSS) heliospheric codes. These examples help refine poorly-known 3-D MHD variables (i.e., density, temperature), and parameters (gamma) by fitting heliospheric remotely-sensed data between the region near the solar surface and in-situ measurements near Earth.

  11. Irradiation Effects Test Series: Test IE-3. Test results report

    International Nuclear Information System (INIS)

    Farrar, L.C.; Allison, C.M.; Croucher, D.W.; Ploger, S.A.

    1977-10-01

    The objectives of the test reported were to: (a) determine the behavior of irradiated fuel rods subjected to a rapid power increase during which the possibility of a pellet-cladding mechanical interaction failure is enhanced and (b) determine the behavior of these fuel rods during film boiling following this rapid power increase. Test IE-3 used four 0.97-m long pressurized water reactor type fuel rods fabricated from previously irradiated fuel. The fuel rods were subjected to a preconditioning period, followed by a power ramp to 69 kW/m at a coolant mass flux of 4920 kg/s-m 2 . After a flow reduction to 2120 kg/s-m 2 , film boiling occurred on the fuel rods. One rod failed approximately 45 seconds after the reactor was shut down as a result of cladding embrittlement due to extensive cladding oxidation. Data are presented on the behavior of these irradiated fuel rods during steady-state operation, the power ramp, and film boiling operation. The effects of a power ramp and power ramp rates on pellet-cladding interaction are discussed. Test data are compared with FRAP-T3 computer model calculations and data from a previous Irradiation Effects test in which four irradiated fuel rods of a similar design were tested. Test IE-3 results indicate that the irradiated state of the fuel rods did not significantly affect fuel rod behavior during normal, abnormal (power ramp of 20 kW/m per minute), and accident (film boiling) conditions

  12. 21 CFR 582.3845 - Stannous chloride.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Stannous chloride. 582.3845 Section 582.3845 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL....3845 Stannous chloride. (a) Product. Stannous chloride. (b) Tolerance. This substance is generally...

  13. Population dynamics of eight-toothed spruce bark beetle (Ips typographus L.) in the region of National Nature Reserve Praděd in 1998 - 2001

    Czech Academy of Sciences Publication Activity Database

    Plašil, P.; Cudlín, Pavel

    2005-01-01

    Roč. 51, č. 8 (2005), s. 359-370 ISSN 1212-4834 R&D Projects: GA MŠk(CZ) OK 389 Institutional research plan: CEZ:AV0Z6087904 Keywords : Ips typographus (L.), population dynamics, management of Ips typographus, NNR Praděd, regulated disintegration Subject RIV: GK - Forestry

  14. 3-D spectral Induced Polarization (IP) imaging: Non-invasive characterization of contaminant plumes. Annual progress report, September 15, 1996 - September 14, 1997

    International Nuclear Information System (INIS)

    Frye, K.M.; Lesmes, D.P.; Morgan, F.D.; Rodi, W.; Shi, W.; Sturrock, J.

    1997-01-01

    'The objective of this project is to develop the scientific basis for characterizing contaminant plumes in the earth''s subsurface using field measurements of induced polarization (IP) effects. The first-year accomplishments are (1) laboratory experiments on fluid-saturated sandstones quantifying the dependence of spectral IP responses on solution chemistry and rock micro-geometry; (2) library research on the current understanding of electromagnetic coupling effects on IP data acquired in the field: and (3) development of prototype forward modeling and inversion algorithms for interpreting IP data in terms of 3-D models of complex resistivity.'

  15. 21 CFR 582.6185 - Calcium acetate.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Calcium acetate. 582.6185 Section 582.6185 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL... Calcium acetate. (a) Product. Calcium acetate. (b) Conditions of use. This substance is generally...

  16. 21 CFR 582.3225 - Calcium sorbate.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Calcium sorbate. 582.3225 Section 582.3225 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL....3225 Calcium sorbate. (a) Product. Calcium sorbate. (b) Conditions of use. This substance is generally...

  17. 21 CFR 582.6195 - Calcium citrate.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Calcium citrate. 582.6195 Section 582.6195 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL... Calcium citrate. (a) Product. Calcium citrate. (b) Conditions of use. This substance is generally...

  18. 21 CFR 582.6219 - Calcium phytate.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Calcium phytate. 582.6219 Section 582.6219 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL... Calcium phytate. (a) Product. Calcium phytate. (b) Conditions of use. This substance is generally...

  19. 21 CFR 582.7187 - Calcium alginate.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Calcium alginate. 582.7187 Section 582.7187 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL... Calcium alginate. (a) Product. Calcium alginate. (b) Conditions of use. This substance is generally...

  20. 21 CFR 582.2227 - Calcium silicate.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Calcium silicate. 582.2227 Section 582.2227 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL... Calcium silicate. (a) Product. Calcium silicate. (b) Tolerance. 2 percent and 5 percent. (c) Limitations...

  1. 21 CFR 582.6193 - Calcium chloride.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Calcium chloride. 582.6193 Section 582.6193 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL... Calcium chloride. (a) Product. Calcium chloride. (b) Conditions of use. This substance is generally...

  2. 21 CFR 582.7351 - Gum tragacanth.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Gum tragacanth. 582.7351 Section 582.7351 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS... tragacanth. (a) Product. Tragacanth (gum tragacanth). (b) Conditions of use. This substance is generally...

  3. 21 CFR 582.3041 - Erythorbic acid.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Erythorbic acid. 582.3041 Section 582.3041 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL....3041 Erythorbic acid. (a) Product. Erythorbic acid. (b) Conditions of use. This substance is generally...

  4. 21 CFR 582.1009 - Adipic acid.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Adipic acid. 582.1009 Section 582.1009 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS....1009 Adipic acid. (a) Product. Adipic acid. (b) [Reserved] (c) Limitations, restrictions, or...

  5. IP Centrex

    OpenAIRE

    Massa Torrelles, Roger

    2006-01-01

    Este documento recoge el trabajo realizado para diseñar e implementar una centralita o PBX para Telefonía IP basada en VoIP (Voz sobre IP) mediante SIP. Proporcionando una alternativa a las actuales centralitas de telefonía, basadas en hardware, que son caras y poco escalables. Se detallan los conceptos VoIP, IP Centrex, se plantean diferentes esquemas para el diseño de IP Centrex y se presentan los detalles de la implementación de IP Centrex. Para la implementación de IP...

  6. Conceptual Design for the In-Pile Test Section(IPS) Improvement

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Jong Min; Shim, Bong Sik; Lee, Chung Young; Chi, Dae Young; Park, Su Ki; Ahn, Sung Ho; Kim, Young Ki; Lee, Kye Hong; Kim, Kwan Hyun

    2009-01-15

    Conceptual design on the IPS, instrumentation and 1/4' Tubing, test fuel supports, test fuel inspection station and inner assembly O-ring replacement was suggested for their improvement. There is a need Jacking bolt on the Top flange for the inner assembly disassemble from the outer assembly and the replacement about the top flange O-ring to metal gasket to secure pressure boundary. Mechanical sealing was suggested instead of brazing. Instrumentation and tubing route should be modified for the reduction of bending and protection from unexpected occasion. Concept on the test fuel inspection station under the consideration of canal dimension. Top flange Bolt handling tool, O-ring replacement platform and O-ring replacement tool was designed for the O-ring replacement at the inner assembly.

  7. Identification of a major IP5 kinase in Cryptococcus neoformans confirms that PP-IP5/IP7, not IP6, is essential for virulence

    OpenAIRE

    Li, Cecilia; Lev, Sophie; Saiardi, Adolfo; Desmarini, Desmarini; Sorrell, Tania C.; Djordjevic, Julianne T.

    2016-01-01

    Fungal inositol polyphosphate (IP) kinases catalyse phosphorylation of IP3 to inositol pyrophosphate, PP-IP5/IP7, which is essential for virulence of Cryptococcus neoformans. Cryptococcal Kcs1 converts IP6 to PP-IP5/IP7, but the kinase converting IP5 to IP6 is unknown. Deletion of a putative IP5 kinase-encoding gene (IPK1) alone (ipk1?), and in combination with KCS1 (ipk1?kcs1?), profoundly reduced virulence in mice. However, deletion of KCS1 and IPK1 had a greater impact on virulence attenua...

  8. Functional-logic simulation of IP-blocks dose functional failures

    Directory of Open Access Journals (Sweden)

    Vyacheslav M. Barbashov

    2017-11-01

    Full Text Available The technique of functional-logical simulation of System-on-Chip (SoC total dose radiation failures is presented based on fuzzy logic sets theory. An analysis of the capabilities of this approach for IP-blocks radiation behavior is carried out along with the analysis of operating modes under irradiation influence on IP-blocks radiation behavior. The following elements of this technique application for simulation of dose radiation failures of various types of IP-units are studied: logical elements, memory units and cells, processors. Examples of criterial membership functions and operability functions construction are given for these IP-units and for various critical parameters characterizing their failures. It is shown that when modeling total dose failures it is necessary to take into account the influence of the functional mode on the model parameters. The technique proposed allows improving the reliability of the SoC radiation hardness estimation, also for the purpose of solving the problems of information security of electronic devices.

  9. 21 CFR 582.1978 - Carnauba wax.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Carnauba wax. 582.1978 Section 582.1978 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS....1978 Carnauba wax. (a) Product. Carnauba wax. (b) Conditions of use. This substance is generally...

  10. 21 CFR 582.1210 - Calcium oxide.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Calcium oxide. 582.1210 Section 582.1210 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS....1210 Calcium oxide. (a) Product. Calcium oxide. (b) Conditions of use. This substance is generally...

  11. 21 CFR 582.1033 - Citric acid.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Citric acid. 582.1033 Section 582.1033 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS....1033 Citric acid. (a) Product. Citric acid. (b) Conditions of use. This substance is generally...

  12. 21 CFR 582.1240 - Carbon dioxide.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Carbon dioxide. 582.1240 Section 582.1240 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS....1240 Carbon dioxide. (a) Product. Carbon dioxide. (b) Conditions of use. This substance is generally...

  13. 21 CFR 582.1061 - Lactic acid.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Lactic acid. 582.1061 Section 582.1061 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS....1061 Lactic acid. (a) Product. Lactic acid. (b) Conditions of use. This substance is generally...

  14. 21 CFR 582.1005 - Acetic acid.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Acetic acid. 582.1005 Section 582.1005 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS....1005 Acetic acid. (a) Product. Acetic acid. (b) Conditions of use. This substance is generally...

  15. 21 CFR 582.3013 - Ascorbic acid.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Ascorbic acid. 582.3013 Section 582.3013 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS... Ascorbic acid. (a) Product. Ascorbic acid. (b) Conditions of use. This substance is generally recognized as...

  16. 21 CFR 582.6099 - Tartaric acid.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Tartaric acid. 582.6099 Section 582.6099 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS... acid. (a) Product. Tartaric acid. (b) Conditions of use. This substance is generally recognized as safe...

  17. 21 CFR 582.3021 - Benzoic acid.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Benzoic acid. 582.3021 Section 582.3021 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS... Benzoic acid. (a) Product. Benzoic acid. (b) Tolerance. This substance is generally recognized as safe for...

  18. 21 CFR 582.3081 - Propionic acid.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Propionic acid. 582.3081 Section 582.3081 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS... Propionic acid. (a) Product. Propionic acid. (b) Conditions of use. This substance is generally recognized...

  19. 21 CFR 582.1095 - Sulfuric acid.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Sulfuric acid. 582.1095 Section 582.1095 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS....1095 Sulfuric acid. (a) Product. Sulfuric acid. (b) Conditions of use. This substance is generally...

  20. 21 CFR 582.3089 - Sorbic acid.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Sorbic acid. 582.3089 Section 582.3089 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS... Sorbic acid. (a) Product. Sorbic acid. (b) Conditions of use. This substance is generally recognized as...

  1. 21 CFR 582.1069 - Malic acid.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Malic acid. 582.1069 Section 582.1069 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS....1069 Malic acid. (a) Product. Malic acid. (b) Conditions of use. This substance is generally recognized...

  2. 21 CFR 582.1091 - Succinic acid.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Succinic acid. 582.1091 Section 582.1091 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS....1091 Succinic acid. (a) Product. Succinic acid. (b) Conditions of use. This substance is generally...

  3. 21 CFR 582.1099 - Tartaric acid.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Tartaric acid. 582.1099 Section 582.1099 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) ANIMAL DRUGS....1099 Tartaric acid. (a) Product. Tartaric acid. (b) Conditions of use. This substance is generally...

  4. Implementasi Sistem IP PBX menggunakan Briker

    Directory of Open Access Journals (Sweden)

    DWI ARYANTA

    2017-06-01

    used in order to make it easier for the Linux operating system to create a program which is using briker IP PBX that works on Linux 2.6 Operating System. After the installation process is done briker on Virtualbox IP PBX network implementation. After implementing the IP PBX network according to the topology, and then do a test call success rate and analysis of Quality of Service (QoS. Measurement of QoS parameters using jitter, delay, and packet loss resulting in the IP PBX system. Jitter value briker fellow users (either on a smartphone or computer has been on the average value of 16.77 ms. While the values ​​obtained packetloss when there is 1 user when a phone caller is 0%. While the percentage of packet loss at user 1 as a telephone receiver is 0.01%. Delay value when communicating between users located at 11.75 ms. Overall value obtained through this study , where the results of testing the QOS parameters in accordance with the standards recommended by the ITU and the QoS values ​​obtained with the results "good". Keywords : Briker, VoIP, QoS, IP PBX, Smartphone.

  5. Irradiated test fuel shipment plan for the LWR MOX fuel irradiation test project

    International Nuclear Information System (INIS)

    Shappert, L.B.; Dickerson, L.S.; Ludwig, S.B.

    1998-01-01

    This document outlines the responsibilities of DOE, DOE contractors, the commercial carrier, and other organizations participating in a shipping campaign of irradiated test specimen capsules containing mixed-oxide (MOX) fuel from the Idaho National Engineering and Environmental Laboratory (INEEL) to the Oak Ridge National Laboratory (ORNL). The shipments described here will be conducted according to applicable regulations of the US Department of Transportation (DOT), US Nuclear Regulatory Commission (NRC), and all applicable DOE Orders. This Irradiated Test Fuel Shipment Plan for the LWR MOX Fuel Irradiation Test Project addresses the shipments of a small number of irradiated test specimen capsules and has been reviewed and agreed to by INEEL and ORNL (as participants in the shipment campaign). Minor refinements to data entries in this plan, such as actual shipment dates, exact quantities and characteristics of materials to be shipped, and final approved shipment routing, will be communicated between the shipper, receiver, and carrier, as needed, using faxes, e-mail, official shipping papers, or other backup documents (e.g., shipment safety evaluations). Any major changes in responsibilities or data beyond refinements of dates and quantities of material will be prepared as additional revisions to this document and will undergo a full review and approval cycle

  6. Evolution of the PI - Productivity Index; Evolucao do IP - Indice de Produtividade

    Energy Technology Data Exchange (ETDEWEB)

    Feitosa, Gilvan Soares [Petroleo Brasileiro S.A. (PETROBRAS), Rio de Janeiro, RJ (Brazil)

    2012-07-01

    The productivity index (PI), the most direct and widely used measure of a well productivity, is defined as the ratio of oil-well rate to the associated pressure drawdown - from average reservoir pressure to bottom hole-flowing-well pressure. It is known that the actual value of PI can only be attained at pseudosteady-state condition, which requires a lot of time (days, or even months), what is not practical for most well tests. For this reason, PI is often obtained from short transient flow test, which gives usually an overestimate of the actual PI. How larger than the actual value is the transient PI? This paper investigates the PI evolution, from the earlier transient well's production period up to the pseudosteady-state flow establishment, under single-phase flow, and later on, as pressure drops below saturation pressure and then oil and gas flow through the reservoir to the well. For analysis of PI during the transient period is defined a dimensionless PI (IP{sub D}), as the ratio of the time-dependent transient PI (IP{sub t}), to the constant pseudosteady-state PI (IP{sub pss}). For transient radial flow, IP{sub D} is developed as a function of dimensionless time, t{sub DA}, and depends on the stabilized drainage area, the Dietz shape factor, the skin factor and the well radius. It is shown that transient PI (IP{sub t}) is always greater than the actual PI (IP{sub pss}) and decreases monotonically with time. At the infinite-acting end IPt reaches the smallest value, which is the closest to the actual pseudosteady-state PI, in the range of 1 to 60% higher, for a broad range of shape factors. The more eccentric the well in the drainage area the more IP{sub t} departs from the actual PI. It is presented a couple of reservoir-limit well test field-cases, where the well was produced long enough until a pseudosteady-state flow was established. Its results, among others, illustrate and substantiate the main theoretical developments of this work. (author)

  7. Numerical study on lateral wall displacement of deep excavation supported by IPS earth retention system

    Directory of Open Access Journals (Sweden)

    Tugen Feng

    2017-12-01

    Full Text Available The objective of this study is to investigate the 3D behavior characteristics of an excavation supported by an innovative prestressed support (IPS earth retention system. A numerical simulation was conducted in order to provide insight into the IPS system behavior by using the FLAC3D package. Prior to the parametric study, validation work was conducted by means of a comparison of the deformation between the field test data and numerical analysis results, and strong agreement was obtained. The reasonable excavation location, layered excavation thickness, and blocked excavation sequence are presented according to variable parameter analysis. In view of the previous findings, certain measurements are proposed in order to control the foundation pit deformation. The results indicate that prestress compensation has a significant effect on the IPS system behavior, while an optimized excavation sequence slightly improves its behavior. With the conclusion proposed based on the numerical results, the aim is to provide reference data for optimization design and the construction sequence. Keywords: FLAC3D, IPS system, Prestress compensation, Layered excavation, Blocked excavation, Deformation control

  8. Fusion Materials Irradiation Test Facility: experimental capabilities and test matrix

    International Nuclear Information System (INIS)

    Opperman, E.K.

    1982-01-01

    This report describes the experimental capabilities of the Fusion Materials Irradiation Test Facility (FMIT) and reference material specimen test matrices. The description of the experimental capabilities and the test matrices has been updated to match the current single test cell facility ad assessed experimenter needs. Sufficient detail has been provided so that the user can plan irradiation experiments and conceptual hardware. The types of experiments, irradiation environment and support services that will be available in FMIT are discussed

  9. HANARO fuel irradiation test(II)

    Energy Technology Data Exchange (ETDEWEB)

    Sohn, D. S.; Kim, H. R.; Chae, H. T.; Lee, B. C.; Lee, C. S.; Kim, B. G.; Lee, C. B.; Hwang, W

    2001-04-01

    In order to fulfill the requirement to prove HANARO fuel integrity when irradiated at a power greater than 112.8 kW/m, which was imposed during HANARO licensing, and to verify the irradiation performance of HANARO fuel, the in-pile irradiation test of HANARO fuel has been performed. Two types of test fuel, the un-instrumented Type A fuel for higher burnup irradiation in shorter period than the driver fuel and the instrumented Type B fuel for higher linear heat rate and precise measurement of irradiation conditions, have been designed and fabricated. The test fuel assemblies were irradiated in HANARO. The two Type A fuel assemblies were intended to be irradiated to medium and high burnup and have been discharged after 69.9 at% and 85.5 at% peak burnup, respectively. Type B fuel assembly was intended to be irradiatied at high power with different instrumentations and achieved a maximum power higher than 120 kW/m without losing its integrity and without showing any irregular behavior. The Type A fuel assemblies were cooled for about 6 months and transported to the IMEF(Irradiated Material Examination Facility) for consequent evaluation. Detailed non-destructive and destructive PIE (Post-Irradiation Examination), such as the measurement of burnup distribution, fuel swelling, clad corrosion, dimensional changes, fuel rod bending strength, micro-structure, etc., has been performed. The measured results have been analysed/compared with the predicted performance values and the design criteria. It has been verified that HANARO fuel maintains proper in-pile performance and integrity even at the high power of 120 kw/m up to the high burnup of 85 at%.

  10. Storage tests with irradiated and non-irradiated onions

    International Nuclear Information System (INIS)

    Gruenewald, T.; Rumpf, G.; Troemel, I.; Bundesforschungsanstalt fuer Ernaehrung, Karlsruhe

    1978-07-01

    The results of several test series on the storage of irradiated and non-irradiated German grown onion are reported. Investigated was the influence of the irradiation conditions such as time and dose and of the storage conditions on sprouting, spoilage, browning of the vegetation centres, composition of the onions, strength and sensorial properties of seven different onion varieties. If the onions were irradiated during the dormancy period following harvest, a dose of 50 Gy (krad) was sufficient to prevent sprouting. Regarding the irradiated onions, it was not possible by variation of the storage conditions within the limits set by practical requirements to extend the dormancy period or to prevent browning of the vegetation centres, however. (orig.) 891 MG 892 RSW [de

  11. Thermostability of IFN-γ and IP-10 release assays for latent infection with Mycobacterium tuberculosis

    DEFF Research Database (Denmark)

    Blauenfeldt, Thomas; Wagner, Dirk; Aabye, Martine Grosos

    2016-01-01

    accuracy of IP-10 release assay and IGRAs. RESULTS: We included 65 patients with confirmed pulmonary tuberculosis and 160 healthy controls from 6 European centres collaborating in the TBnet. In patients, IP-10 responses increased 1.07 (IQR 0.90-1.36) fold and IFN-γ responses decreased 0.88 (IQR 0......INTRODUCTION: Interferon-γ (IFN-γ) inducible protein 10kD (IP-10) and IFN-γ release assays (IGRAs) are immunodiagnostic tests aiming to identify the presence of specific cellular immune responses, interpreted as markers for latent infection with Mycobacterium tuberculosis. Incubation at higher...

  12. Irradiation Effects Test Series: Test IE-3. Test results report. [PWR

    Energy Technology Data Exchange (ETDEWEB)

    Farrar, L. C.; Allison, C. M.; Croucher, D. W.; Ploger, S. A.

    1977-10-01

    The objectives of the test reported were to: (a) determine the behavior of irradiated fuel rods subjected to a rapid power increase during which the possibility of a pellet-cladding mechanical interaction failure is enhanced and (b) determine the behavior of these fuel rods during film boiling following this rapid power increase. Test IE-3 used four 0.97-m long pressurized water reactor type fuel rods fabricated from previously irradiated fuel. The fuel rods were subjected to a preconditioning period, followed by a power ramp to 69 kW/m at a coolant mass flux of 4920 kg/s-m/sup 2/. After a flow reduction to 2120 kg/s-m/sup 2/, film boiling occurred on the fuel rods. One rod failed approximately 45 seconds after the reactor was shut down as a result of cladding embrittlement due to extensive cladding oxidation. Data are presented on the behavior of these irradiated fuel rods during steady-state operation, the power ramp, and film boiling operation. The effects of a power ramp and power ramp rates on pellet-cladding interaction are discussed. Test data are compared with FRAP-T3 computer model calculations and data from a previous Irradiation Effects test in which four irradiated fuel rods of a similar design were tested. Test IE-3 results indicate that the irradiated state of the fuel rods did not significantly affect fuel rod behavior during normal, abnormal (power ramp of 20 kW/m per minute), and accident (film boiling) conditions.

  13. HANARO fuel irradiation test (II): revision

    Energy Technology Data Exchange (ETDEWEB)

    Sohn, D. S.; Kim, H.; Chae, H. T.; Lee, C. S.; Kim, B. G.; Lee, C. B

    2001-04-01

    In order to fulfill the requirement to prove HANARO fuel integrity when irradiated at a power greater than 112.8 kW/m, which was imposed during HANARO licensing, and to verify the irradiation performance of HANARO fuel, the in-pile irradiation test of HANARO fuel has been performed. Two types of test fuel, the un-instrumented Type A fuel for higher burnup irradiation in shorter period than the driver fuel and the instrumented Type B fuel for higher linear heat rate and precise measurement of irradiation conditions, have been designed and fabricated. The test fuel assemblies were irradiated in HANARO. The two Type A fuel assemblies were intended to be irradiated to medium and high burnup and have been discharged after 69.9 at% and 85.5 at% peak burnup, respectively. Type B fuel assembly was intended to be irradiated at high power with different instrumentations and achieved a maximum power higher than 120 kW/m without losing its integrity and without showing any irregular behavior. The Type A fuel assemblies were cooled for about 6 months and transported to the IMEF(Irradiated Material Examination Facility) for consequent evaluation. Detailed non-destructive and destructive PIE (Post-Irradiation Examination), such as the measurement of burnup distribution, fuel swelling, clad corrosion, dimensional changes, fuel rod bending strength, micro-structure, etc., has been performed. The measured results have been analysed/compared with the predicted performance values and the design criteria. It has been verified that HANARO fuel maintains proper in-pile performance and integrity even at the high power of 120 kw/m up to the high burnup of 85 at%. This report is the revision of KAERI/TR-1816/2001 on the irradiation test for HANARO fuel.

  14. Irradiation enhanced diffusion and irradiation creep tests in stainless steel alloys

    International Nuclear Information System (INIS)

    Loelgen, R.H.; Cundy, M.R.; Schuele, W.

    1977-01-01

    A review is given of investigations on the rate of phase changes during neutron and electron irradiation in many different fcc alloys showing either precipitation or ordering. The diffusion rate was determined as a function of the irradiation flux, the irradiation temperature and the irradiation dose. It was found that the radiation enhanced diffusion in all the investigated alloys is nearly temperature independent and linearly dependent on the flux. From these results conclusions were drawn concerning the properties of point defects and diffusion mechanisms rate determining during irradiation, which appears to be of a common nature for fcc alloys having a similar structure to those investigated. It has been recognized that the same dependencies which are found for the diffusion rate were also observed for the irradiation creep rate in stainless steels, as reported in literature. On the basis of this observation a combination of measurements is suggested, of radiation enhanced diffusion and radiation enhanced creep in stainless steel alloys. The diffusion tests will be performed at the Euratom Joint Research Centre in Ispra, Italy, and the irradiation creep tests will be carried out in the High Flux Reactor /9/ of the Euratom Joint Research Centre in Petten, The Netherlands. In order to investigate irradiation creep on many samples at a time two special rigs were developed which are distinguished only by the mode of stress applied to the steel specimens. In the first type of rig about 50 samples can be tested uniaxially under tension with various combinations of irradiation temperature and stress. The second type of rig holds up to 70 samples which are tested in bending, again with various combinations of irradiation temperature and stress

  15. Design criteria and fabrication in-pile test section of HANARO fuel test loop

    Energy Technology Data Exchange (ETDEWEB)

    Kim, J. Y.

    1997-10-01

    Safety state fuel test loop will be equipped in HANARO to obtain the development and betterments of advanced fuel and materials through the irradiation tests. The objective of this study is to determine the design criteria and technical specification of in-pile test section and to specify the manufacturing requirements of in-pile test section. HANARO fuel test loop was designed to meet the CANDU and PWR fuel testing and in-pile section will be manufactured and installed in HANARO. The design criteria and technical specification of in-pile test section could be used the fuel and materials design with for irradiation testing IPS of HANARO fuel test loop. This results will become guidances for the planning and programming of irradiation testing. (author). 12 refs., tabs., figs.

  16. Neutron Flux Characterization of Irradiation Holes for Irradiation Test at HANARO

    Directory of Open Access Journals (Sweden)

    Yang Seong Woo

    2016-01-01

    Full Text Available The High flux Advanced Neutron Application ReactOr (HANARO is a unique research reactor in the Republic of Korea, and has been used for irradiation testing since 1998. To conduct irradiation tests for nuclear materials, the irradiation holes of CT and OR5 have been used due to a high fast-neutron flux. Because the neutron flux must be accurately calculated to evaluate the neutron fluence of irradiated material, it was conducted using MCNP. The neutron flux was measured using fluence monitor wires to verify the calculated result. Some evaluations have been conducted, however, more than 20% errors have frequently occurred at the OR irradiation hole, while a good agreement between the calculated and measured data was shown at the CT irradiation hole.

  17. Post irradiation test report of irradiated DUPIC simulated fuel

    International Nuclear Information System (INIS)

    Yang, Myung Seung; Jung, I. H.; Moon, J. S. and others

    2001-12-01

    The post-irradiation examination of irradiated DUPIC (Direct Use of Spent PWR Fuel in CANDU Reactors) simulated fuel in HANARO was performed at IMEF (Irradiated Material Examination Facility) in KAERI during 6 months from October 1999 to March 2000. The objectives of this post-irradiation test are i) the integrity of the capsule to be used for DUPIC fuel, ii) ensuring the irradiation requirements of DUPIC fuel at HANARO, iii) performance verification in-core behavior at HANARO of DUPIC simulated fuel, iv) establishing and improvement the data base for DUPIC fuel performance verification codes, and v) establishing the irradiation procedure in HANARO for DUPIC fuel. The post-irradiation examination performed are γ-scanning, profilometry, density, hardness, observation the microstructure and fission product distribution by optical microscope and electron probe microanalyser (EPMA)

  18. Characterization and Beam Tests Results of Non-Uniformly Irradiated 3D Pixel Sensors for HEP Experiments

    International Nuclear Information System (INIS)

    Lopez, I.; Grinstein, S.; Micelli, A.; Tsiskaridze, S.

    2013-06-01

    3D Pixel detectors, with cylindrical electrodes that penetrate the silicon substrate, offer advantages over standard planar sensors in terms of radiation hardness, since the charge collection distance can be reduced independently of the bulk thickness. In the framework of the ATLAS Forward Physics (AFP) program, work has been carried out to study the suitability of 3D pixel devices for forward proton tracking. The AFP tracker unit will consist of an array of five pixel sensors placed at 2-3 mm from the Large Hadron Collider (LHC) proton beam. The proximity to the beam is essential for the AFP physics program as it directly increases the sensitivity of the experiment. Thus, there are two critical requirements for the AFP pixel detector. First, the dead region of the sensor has to be minimized. Second, the device has to be able to cope with a very inhomogeneous radiation distribution. Recent results of the characterization and beam test studies of in-homogeneously irradiated 3D pixel sensors produced at CNM-Barcelona will be presented. (authors)

  19. HRB-22 irradiation phase test data report

    International Nuclear Information System (INIS)

    Montgomery, F.C.; Acharya, R.T.; Baldwin, C.A.; Rittenhouse, P.L.; Thoms, K.R.; Wallace, R.L.

    1995-03-01

    Irradiation capsule HRB-22 was a test capsule containing advanced Japanese fuel for the High Temperature Test Reactor (HTTR). Its function was to obtain fuel performance data at HTTR operating temperatures in an accelerated irradiation environment. The irradiation was performed in the High Flux Isotope Reactor (HFIR) at the Oak Ridge National Laboratory (ORNL). The capsule was irradiated for 88.8 effective full power days in position RB-3B of the removable beryllium (RB) facility. The maximum fuel compact temperature was maintained at or below the allowable limit of 1300 degrees C for a majority of the irradiation. This report presents the data collected during the irradiation test. Included are test thermocouple and gas flow data, the calculated maximum and volume average temperatures based on the measured graphite temperatures, measured gaseous fission product activity in the purge gas, and associated release rate-to-birth rate (R/B) results. Also included are quality assurance data obtained during the test

  20. Non-destructive tests of capsules for JMTR irradiation examination

    International Nuclear Information System (INIS)

    Tanaka, Hidetaka; Nagao, Yoshiharu; Sato, Masashi; Osawa, Kenji

    2007-03-01

    Irradiation examination are increasing in advanced irradiation research for accurate prediction control and evaluation of irradiation parameter such as neutron fluence, etc. by using JMTR. Irradiation capsule internals are therefore structurally complicated recently. This report described the procedure of non destructive tests such as radiographic test, penetrant test, ultrasonic test, etc. for inspection of irradiation capsules in JMTR, and the result of Test-case of confirmation procedure for internal parts of irradiation capsules. (author)

  1. 21 CFR 582.2122 - Aluminum calcium silicate.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Aluminum calcium silicate. 582.2122 Section 582.2122 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED....2122 Aluminum calcium silicate. (a) Product. Aluminum calcium silicate. (b) Tolerance. 2 percent. (c...

  2. Insulation irradiation test programme for the Compact Ignition Tokamak

    International Nuclear Information System (INIS)

    McManamy, T.J.; Kanemoto, G.; Snook, P.

    1991-01-01

    In a programme to evaluate the effects of radiation exposure on the electrical insulation for the toroidal field coils of the Compact Ignition Tokamak, three types of boron-free insulation were irradiated at room temperature in the Advanced Technology Reactor (ATR) and tested at the Idaho National Engineering Laboratory. The materials were Spaulrad-S, Shikishima PG5-1 and Shikishima PG3-1. The first two use a bismaleimide resin and the third an aromatic amine hardened epoxy. Spaulrad-S is a two-dimensional (2-D) weave of S-glass, while the others are 3-D weaves of T-glass. Flexure and shear/compression samples were irradiated to ≅ 5 x 10 9 and 3 x 10 10 rad with 35-40% of the total dose from neutrons. The shear/compression samples were tested in pairs by applying an average compression of 345 MPa and then a shear load. After static tests were completed, fatigue testing was performed by cycling the shear load for up to 30000 cycles with a constant compression. The static shear strength of the samples that did not fail was then determined. Generally, shear strengths of the order of 120 MPa were measured. The behaviour of the flexure and shear/compression samples was significantly different; large reductions in the flexure strength were observed, while the shear strength stayed the same or increased slightly. The 3-D weave material demonstrated higher strength and significantly less radiation damage than the 2-D material in flexure but performed almost identically when tested with combined shear and compression. The epoxy system was much more sensitive to fatigue damage than the bismaleimide materials. No swelling was measured; however, the epoxy samples did twist slightly. (author)

  3. HPC Access Using KVM over IP

    Science.gov (United States)

    2007-06-08

    Lightwave VDE /200 KVM-over-Fiber (Keyboard, Video and Mouse) devices installed throughout the TARDEC campus. Implementation of this system required...development effort through the pursuit of an Army-funded Phase-II Small Business Innovative Research (SBIR) effort with IP Video Systems (formerly known as...visualization capabilities of a DoD High- Performance Computing facility, many advanced features are necessary. TARDEC-HPC’s SBIR with IP Video Systems

  4. Present status of ESNIT (energy selective neutron irradiation test facility) program

    International Nuclear Information System (INIS)

    Noda, K.; Ohno, H.; Sugimoto, M.; Kato, Y.; Matsuo, H.; Watanabe, K.; Kikuchi, T.; Sawai, T.; Usui, T.; Oyama, Y.; Kondo, T.

    1994-01-01

    The present status of technical studies of a high energy neutron irradiation facility, ESNIT (energy selective neutron irradiation test facility), is summarized. Technological survey and feasibility studies of ESNIT have continued since 1988. The results of technical studies of the accelerator, the target and the experimental systems in ESNIT program were reviewed by an International Advisory Committee in February 1993. Recommendations for future R and D on ESNIT program are also summarized in this paper. ((orig.))

  5. RECH-1 test fuel irradiation status report

    International Nuclear Information System (INIS)

    Marin, J.; Lisboa, J.; Olivares, L.; Chavez, J.

    2005-01-01

    Since May 2003, one RECH-1 fuel element has been submitted to irradiation at the HFR-Petten, Holland. By November 2004 the irradiation has achieved its pursued goal of 55% burn up. This irradiation qualification service will finish in the year 2005 with PIE tests, as established in a contractual agreement between the IAEA, NRG, and CCHEN. This report presents the objectives and the current results of this fuel qualification under irradiation. Besides, a brief description of CHI/4/021, IAEA's Technical Cooperation Project that has supported this irradiation test, is also presented here. (author)

  6. Introduction to the study of an optimal control for irradiation loops of the reactor Pegase; Introduction a l'etude d'une commande optimale des boucles d'irradiation du reacteur Pegase

    Energy Technology Data Exchange (ETDEWEB)

    Guintrand, C [Commissariat a l' Energie Atomique, Cadarache (France). Centre d' Etudes Nucleaires

    1968-07-01

    The control system under consideration is made up of: a regulation unit consisting of a conventional nonlinear looped circuit for static tests, a cycling unit operating in open loop for dynamic tests. After a definition of a mathematical model for an irradiation loop, the behaviour of the regulation unit is studied, first of all theoretically using three-dimensional topological methods, and then by analogue simulation. A prototype unit is under construction and its principal characteristics are given. Finally, as far as the cycling unit is concerned, the first tests involving self-instruction technique, are described. (author) [French] Le systeme de commande envisage se compose de r: une unite de regulation se presentant sous la forme d'un circuit boucle classique non-lineaire, pour les essais statiques, une unite de cyclage fonctionnant en boucle ouverte, pour les essais dynamiques. Apres avoir defini un modele mathematique d'une boucle d'irradiation, on etudie le comportement de l'unite de regulation d'abord de facon theorique par les methodes topologiques a trois dimensions, puis par une simulation analogique. Une unite prototype est en cours de realisation, les principales caracteristiques en sont donnees. Enfin, en ce qui concerne l'unite de cyclage, les premiers essais effectues faisant appel aux techniques d'autoapprentissage, sont decrits. (auteur)

  7. Disk-bend ductility tests for irradiated materials

    International Nuclear Information System (INIS)

    Klueh, R.L.; Braski, D.N.

    1984-01-01

    We modified the HEDL disk-bend test machine and are using it to qualitatively screen alloys that are susceptible to embrittlement caused by irradiation. Tests designed to understand the disk-bend test in relation to a uniaxial test are discussed. Selected results of tests of neutron-irradiated material are also presented

  8. Irradiation enhanced diffusion and irradiation creep tests in stainless steel alloys

    International Nuclear Information System (INIS)

    Loelgen, R.H.; Cundy, M.R.; Schuele, W.

    1977-01-01

    A review is given of investigations on the rate of phase changes during neutron and electron irradiation in many different fcc alloys showing either precipitation or ordering. The diffusion rate was determined as a function of the irradiation flux, the irradiation temperature and the irradiation dose. It was found that the radiation enhanced diffusion in all the investigated alloys is nearly temperature independent and linearly dependent on the flux. From these results conclusions were drawn concerning the properties of point defects and diffusion mechanisms rate determining during irradiation, which appears to be of a common nature for fcc alloys having a similar structure to those investigated. It has been recognized that the same dependencies which are found for the diffusion rate were also observed for the irradiation creep rate in stainless steels, as reported in literature. On the basis of this obervation a combination of measurements is suggested, of radiation enhanced diffusion and radiation enhanced creep in stainless steel alloys. Measurements of radiation enhanced diffusion are less time consuming and expensive than irradiation creep tests and information on this property can be obtained rather quickly, prior to the selection of stainless steel alloys for creep tests. In order to investigate irradiation creep on many samples at a time two special rigs were developed which are distinguished only by the mode of stress applied to the steel specimens. Finally, a few uniaxial tensile creep tests will be performed in fully instrumented rigs. (Auth.)

  9. 21 CFR 582.80 - Trace minerals added to animal feeds.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Trace minerals added to animal feeds. 582.80 Section 582.80 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES... Provisions § 582.80 Trace minerals added to animal feeds. These substances added to animal feeds as...

  10. Effect of different surface treatments on roughness of IPS Empress 2 ceramic.

    Science.gov (United States)

    Kara, Haluk Baris; Dilber, Erhan; Koc, Ozlem; Ozturk, A Nilgun; Bulbul, Mehmet

    2012-03-01

    The aim of this study was to evaluate the influence of different surface treatments (air abrasion, acid etching, laser irradiation) on the surface roughness of a lithium-disilicate-based core ceramic. A total of 40 discs of lithium disilicate-based core ceramic (IPS Empress 2; Ivoclar Vivadent, Schaan, Liechtenstein) were prepared (10 mm in diameter and 1 mm in thickness) according to the manufacturer's instructions. Specimens were divided into four groups (n = 10), and the following treatments were applied: air abrasion with alumina particles (50 μm), acid etching with 5% hydrofluoric acid, Nd:YAG laser irradiation (1 mm distance, 100 mJ, 20 Hz, 2 W) and Er:YAG laser irradiation (1 mm distance, 500 mJ, 20 Hz, 10 W). Following determination of surface roughness (R(a)) by profilometry, specimens were examined with atomic force microscopy. The data were analysed by one-way analysis of variance (ANOVA) and Tukey HSD test (α = 0.05). One-way ANOVA indicated that surface roughness following air abrasion was significantly different from the surface roughness following laser irradiation and acid etching (P 0.05). Air abrasion increased surface roughness of lithium disilicate-based core ceramic surfaces more effectively than acid-etching and laser irradiation.

  11. Design of in-pile section monitoring system in fuel test loop

    Energy Technology Data Exchange (ETDEWEB)

    Sim, B. S.; Park, K. N.; Park, S. K.; Chi, D. Y.; Lee, J. M.; Ahn, S. H.; Lee, C. Y.; Kim, Y. J. [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of)

    2005-07-01

    In this paper a brief summary of the monitoring system of In-Pile Section(IPS) is described. To meet the user requirements on the test fuel and irradiation conditions, various instruments are installed on the test fuel pin itself and the appropriate locations in IPS. The requirements and descriptions for instruments, gas supply system, and the data acquisition system to sample and record parameters are described.

  12. VoIP Security

    OpenAIRE

    Fontanini, Piero

    2008-01-01

    VOIP or Voice Over Internet Protocol is a common term for phone service over IP based networks. There are much information about VoIP and some of how VoIP can be secured. There is however no standard for VoIP and no general solution for VoIP Security. The security in VoIP systems today are often non existing or in best case weak and often based on proprietary solutions. This master thesis investigates threats to VoIP system and describes existing alternatives for securing Vo...

  13. Characterization of proton irradiated 3D-DDTC pixel sensor prototypes fabricated at FBK

    CERN Document Server

    La Rosa, A; Cobal, M; Betta, G -F Dalla; Da Via, C; Darbo, G; Gallrapp, C; Gemme, C; Huegging, F; Janssen, J; Micelli, A; Pernegger, H; Povoli, M; Wermes, N; Zorzi, N

    2012-01-01

    In this paper we discuss results relevant to 3D Double-Side Double Type Column (3D-DDTC) pixel sensors fabricated at FBK (Trento, Italy) and oriented to the ATLAS upgrade. Some assemblies of these sensors featuring different columnar electrode configurations (2, 3, or 4 columns per pixel) and coupled to the ATLAS FEI3 read-out chip were irradiated up to large proton fluences and tested in laboratory with radioactive sources. In spite of the non optimized columnar electrode overlap, sensors exhibit reasonably good charge collection properties up to an irradiation fluence of 2 x 10**15 neq/cm2, while requiring bias voltages in the order of 100 V. Sensor operation is further investigated by means of TCAD simulations which can effectively explain the basic mechanisms responsible for charge loss after irradiation.

  14. 3-D reconstructions of the early-November 2004 CDAW geomagnetic storms: analysis of Ooty IPS speed and density data

    Directory of Open Access Journals (Sweden)

    M. M. Bisi

    2009-12-01

    Full Text Available Interplanetary scintillation (IPS remote-sensing observations provide a view of the solar wind covering a wide range of heliographic latitudes and heliocentric distances from the Sun between ~0.1 AU and 3.0 AU. Such observations are used to study the development of solar coronal transients and the solar wind while propagating out through interplanetary space. They can also be used to measure the inner-heliospheric response to the passage of coronal mass ejections (CMEs and co-rotating heliospheric structures. IPS observations can, in general, provide a speed estimate of the heliospheric material crossing the observing line of site; some radio antennas/arrays can also provide a radio scintillation level. We use a three-dimensional (3-D reconstruction technique which obtains perspective views from outward-flowing solar wind and co-rotating structure as observed from Earth by iteratively fitting a kinematic solar wind model to these data. Using this 3-D modelling technique, we are able to reconstruct the velocity and density of CMEs as they travel through interplanetary space. For the time-dependent model used here with IPS data taken from the Ootacamund (Ooty Radio Telescope (ORT in India, the digital resolution of the tomography is 10° by 10° in both latitude and longitude with a half-day time cadence. Typically however, the resolutions range from 10° to 20° in latitude and longitude, with a half- to one-day time cadence for IPS data dependant upon how much data are used as input to the tomography. We compare reconstructed structures during early-November 2004 with in-situ measurements from the Wind spacecraft orbiting the Sun-Earth L1-Point to validate the 3-D tomographic reconstruction results and comment on how these improve upon prior reconstructions.

  15. Qualification of Type IP-2, Type IP-3 and Type A packages for radioactive liquid shipments

    International Nuclear Information System (INIS)

    Marcu, L.; Sullivan, G.; Lo, K.K.

    2006-01-01

    Commercial products such as pails, drums or bulk containers can be used for radioactive materials transportation if they can be shown to meet the regulatory requirements. Ontario Power Generation (OPG) has successfully tested and qualified several off-the-shelf containers as Type IP-2, Type IP-3 and Type A packages for liquids in accordance with the International and Canadian Regulations. This paper describes the testing and qualification of these commercial products, and discusses the problems encountered and lessons learned during this process. (author)

  16. Securing VoIP keeping your VoIP network safe

    CERN Document Server

    (Bud) Bates, Regis J Jr

    2015-01-01

    Securing VoIP: Keeping Your VoIP Network Safe will show you how to take the initiative to prevent hackers from recording and exploiting your company's secrets. Drawing upon years of practical experience and using numerous examples and case studies, technology guru Bud Bates discusses the business realities that necessitate VoIP system security and the threats to VoIP over both wire and wireless networks. He also provides essential guidance on how to conduct system security audits and how to integrate your existing IT security plan with your VoIP system and security plans, helping you prevent

  17. Atomic force microscopy and mechanical testing of bovine pericardium irradiated to radiotherapy doses

    International Nuclear Information System (INIS)

    Daar, Eman; Kaabar, W.; Woods, E.; Lei, C.; Nisbet, A.; Bradley, D.A.

    2014-01-01

    Within the context of radiotherapy our work investigates the feasibility of identifying changes in structural and biomechanical properties of pericardium resulting from exposure to penetrating photon irradiation. Collagen fibres extracted from bovine pericardium were chosen as a model of pericardium extracellular matrix as these form the main fibrous component of the medium. Tests of mechanical properties, controlled by the various structural elements of the tissues, were performed on frontal pericardium, including uni-axial tests and atomic force microscopy (AFM). While the irradiated collagen fibres showed no significant change in D-band spacing up to doses of 80 Gy, the fibre width was found to increase by 34±9% at 80 Gy when compared with that for un-irradiated samples. - Highlights: • Methods for identifying changes in tissue biophysical properties following photon irradiation. • Tests made using collagen fibres extracted from bovine pericardium. • Sensitivity of uni-axial tests and atomic force microscopy (AFM) investigated. • Radiotherapy doses investigated up to 80 Gy, delivered by 6 MV photons

  18. HIGH-TEMPERATURE SAFETY TESTING OF IRRADIATED AGR-1 TRISO FUEL

    Energy Technology Data Exchange (ETDEWEB)

    Stempien, John D.; Demkowicz, Paul A.; Reber, Edward L.; Chrisensen, Cad L.

    2016-11-01

    High-Temperature Safety Testing of Irradiated AGR-1 TRISO Fuel John D. Stempien, Paul A. Demkowicz, Edward L. Reber, and Cad L. Christensen Idaho National Laboratory, P.O. Box 1625 Idaho Falls, ID 83415, USA Corresponding Author: john.stempien@inl.gov, +1-208-526-8410 Two new safety tests of irradiated tristructural isotropic (TRISO) coated particle fuel have been completed in the Fuel Accident Condition Simulator (FACS) furnace at the Idaho National Laboratory (INL). In the first test, three fuel compacts from the first Advanced Gas Reactor irradiation experiment (AGR-1) were simultaneously heated in the FACS furnace. Prior to safety testing, each compact was irradiated in the Advanced Test Reactor to a burnup of approximately 15 % fissions per initial metal atom (FIMA), a fast fluence of 3×1025 n/m2 (E > 0.18 MeV), and a time-average volume-average (TAVA) irradiation temperature of about 1020 °C. In order to simulate a core-conduction cool-down event, a temperature-versus-time profile having a peak temperature of 1700 °C was programmed into the FACS furnace controllers. Gaseous fission products (i.e., Kr-85) were carried to the Fission Gas Monitoring System (FGMS) by a helium sweep gas and captured in cold traps featuring online gamma counting. By the end of the test, a total of 3.9% of an average particle’s inventory of Kr-85 was detected in the FGMS traps. Such a low Kr-85 activity indicates that no TRISO failures (failure of all three TRISO layers) occurred during the test. If released from the compacts, condensable fission products (e.g., Ag-110m, Cs-134, Cs-137, Eu-154, Eu-155, and Sr-90) were collected on condensation plates fitted to the end of the cold finger in the FACS furnace. These condensation plates were then analyzed for fission products. In the second test, five loose UCO fuel kernels, obtained from deconsolidated particles from an irradiated AGR-1 compact, were heated in the FACS furnace to a peak temperature of 1600 °C. This test had two

  19. Impact of artefact removal on ChIP quality metrics in ChIP-seq and ChIP-exo data.

    Directory of Open Access Journals (Sweden)

    Thomas Samuel Carroll

    2014-04-01

    Full Text Available With the advent of ChIP-seq multiplexing technologies and the subsequent increase in ChIP-seq throughput, the development of working standards for the quality assessment of ChIP-seq studies has received significant attention. The ENCODE consortium’s large scale analysis of transcription factor binding and epigenetic marks as well as concordant work on ChIP-seq by other laboratories has established a new generation of ChIP-seq quality control measures. The use of these metrics alongside common processing steps has however not been evaluated. In this study, we investigate the effects of blacklisting and removal of duplicated reads on established metrics of ChIP-seq quality and show that the interpretation of these metrics is highly dependent on the ChIP-seq preprocessing steps applied. Further to this we perform the first investigation of the use of these metrics for ChIP-exo data and make recommendations for the adaptation of the NSC statistic to allow for the assessment of ChIP-exo efficiency.

  20. Digital signage sobre IP

    OpenAIRE

    Casademont Filella, Albert

    2012-01-01

    Projecte que versa sobre el disseny i la implementació d'un sistema de Digital Signage (Cartelleria Digital) sobre IP, creant un gestor que permeti controlar de forma remota tot un conjunt de petits dispositius connectats a pantalles que emeten continguts multimèdia com vídeos, imatges, feeds rss...

  1. Characterization of proton irradiated 3D-DDTC pixel sensor prototypes fabricated at FBK

    Energy Technology Data Exchange (ETDEWEB)

    La Rosa, A., E-mail: alessandro.larosa@cern.ch [CERN, Geneva 23, CH-1211 (Switzerland); Boscardin, M. [Fondazione Bruno Kessler, FBK-CMM, Via Sommarive 18, I-38123 Trento (Italy); Cobal, M. [Universita degli Studi di Udine and INFN Trieste, Gruppo Collegato di Udine, Via delle Scienze 208, I-33100 Udine (Italy); Dalla Betta, G.-F. [DISI, Universita degli Studi di Trento and INFN Padova, Gruppo Collegato d Trento, Via Sommarive 14, I-38123 Trento (Italy); Da Via, C. [School of Physics and Astronomy, University of Manchester, Oxford Road, Manchester M13 9PL (United Kingdom); Darbo, G. [INFN Sezione di Genova, Via Dodecaneso 33, I-14146 Genova (Italy); Gallrapp, C. [CERN, Geneva 23, CH-1211 (Switzerland); Gemme, C. [INFN Sezione di Genova, Via Dodecaneso 33, I-14146 Genova (Italy); Huegging, F.; Janssen, J. [Physikalisches Institut, Universitaet Bonn, Nussallee 12, D-53115 Bonn (Germany); Micelli, A. [Universita degli Studi di Udine and INFN Trieste, Gruppo Collegato di Udine, Via delle Scienze 208, I-33100 Udine (Italy); Pernegger, H. [CERN, Geneva 23, CH-1211 (Switzerland); Povoli, M. [DISI, Universita degli Studi di Trento and INFN Padova, Gruppo Collegato d Trento, Via Sommarive 14, I-38123 Trento (Italy); Wermes, N. [Physikalisches Institut, Universitaet Bonn, Nussallee 12, D-53115 Bonn (Germany); Zorzi, N. [Fondazione Bruno Kessler, FBK-CMM, Via Sommarive 18, I-38123 Trento (Italy)

    2012-07-21

    In this paper we discuss results relevant to 3D Double-Side Double Type Column (3D-DDTC) pixel sensors fabricated at FBK (Trento, Italy) and oriented to the ATLAS upgrade. Some assemblies of these sensors featuring different columnar electrode configurations (2, 3, or 4 columns per pixel) and coupled to the ATLAS FEI3 read-out chip were irradiated up to large proton fluences and tested in laboratory with radioactive sources. In spite of the non-optimized columnar electrode overlap, sensors exhibit reasonably good charge collection properties up to an irradiation fluence of 2 Multiplication-Sign 10{sup 15}n{sub eq}cm{sup -2}, while requiring bias voltages in the order of 100 V. Sensor operation is further investigated by means of TCAD simulations which can effectively explain the basic mechanisms responsible for charge loss after irradiation.

  2. Hypermethylated ZNF582 and PAX1 genes in mouth rinse samples as biomarkers for oral dysplasia and oral cancer detection.

    Science.gov (United States)

    Cheng, Shih-Jung; Chang, Chi-Feng; Ko, Hui-Hsin; Lee, Jang-Jaer; Chen, Hsin-Ming; Wang, Huei-Jen; Lin, Hsiao-Shan; Chiang, Chun-Pin

    2018-02-01

    Effective biomarkers for oral cancer screening are important for early diagnosis and treatment of oral cancer. Oral epithelial cell samples collected by mouth rinse were obtained from 65 normal control subjects, 108 patients with oral potentially malignant disorders, and 94 patients with oral squamous cell carcinoma (OSCC). Methylation levels of zinc-finger protein 582 (ZNF582) and paired-box 1 (PAX1) genes were quantified by real-time methylation-specific polymerase chain reaction after bisulfite conversion. An abrupt increase in methylated ZNF582 (ZNF582 m ) and PAX1 (PAX1 m ) levels and positive rates from mild dysplasia to moderate/severe dysplasia, indicating that both ZNF582 m and PAX1 m are effective biomarkers for differentiating moderate dysplasia or worse (MODY+) oral lesions. When ZNF582 m /PAX1 m tests were used for identifying MODY+ oral lesions, the sensitivity, specificity, and odds ratio (OR) were 0.65/0.64, 0.75/0.82, and 5.6/8.0, respectively. Hypermethylated ZNF582 and PAX1 genes in oral epithelial cells collected by mouth rinse are effective biomarkers for the detection of oral dysplasia and oral cancer. © 2017 Wiley Periodicals, Inc.

  3. The Design and Manufacturing Report of Plug Type Non-Instrumented Rig for Irradiation Test in HANARO OR Hole

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Dae Ho; Bang, Je Geon; Lim, Ik Sung; Kim, Sun Ki; Yang, Yong Sik; Song, Kun Woo

    2008-09-15

    This project is developed the plug type non-instrumented irradiation test rig of the advanced nuclear fuel in HANARO for pursuit advanced performance in High Performance Fuel Technology Development as a part Nuclear Mid and Long-term R and D Program. This irradiation rig was confirmed the integrity and HANARO core compatibility by the optimum design and the thermal hydraulic out-pile test in FIVPET. The characteristic of plug type non-instrument rig is to possible irradiation test of variable in-pile condition and reduced the wastes for reusable as function. This plug type non-instrumented rig was satisfied the quality assurance requirements and written out the end of manufacturing report. This plug type non-instrumented rig is adopt to the irradiation test for nuclear fuel irradiation test in HANARO OR hole.

  4. Briefer assessment of social network drinking: A test of the Important People Instrument-5 (IP-5).

    Science.gov (United States)

    Hallgren, Kevin A; Barnett, Nancy P

    2016-12-01

    The Important People instrument (IP; Longabaugh et al., 2010) is one of the most commonly used measures of social network drinking. Although its reliability and validity are well-supported, the length of the instrument may limit its use in many settings. The present study evaluated whether a briefer, 5-person version of the IP (IP-5) adequately reproduces scores from the full IP. College freshmen (N = 1,053) reported their own past-month drinking, alcohol-related consequences, and information about drinking in their close social networks at baseline and 1 year later. From this we derived network members' drinking frequency, percentage of drinkers, and percentage of heavy drinkers, assessed for up to 10 (full IP) or 5 (IP-5) network members. We first modeled the expected concordance between full-IP scores and scores from simulated shorter IP instruments by sampling smaller subsets of network members from full IP data. Then, using quasi-experimental methods, we administered the full IP and IP-5 and compared the 2 instruments' score distributions and concurrent and year-lagged associations with participants' alcohol consumption and consequences. Most of the full-IP variance was reproduced from simulated shorter versions of the IP (ICCs ≥ 0.80). The full IP and IP-5 yielded similar score distributions, concurrent associations with drinking (r = 0.22 to 0.52), and year-lagged associations with drinking. The IP-5 retains most of the information about social network drinking from the full IP. The shorter instrument may be useful in clinical and research settings that require frequent measure administration, yielding greater temporal resolution for monitoring social network drinking. (PsycINFO Database Record (c) 2017 APA, all rights reserved).

  5. Design and manufacturing of non-instrumented capsule for advanced PWR fuel pellet irradiation test in HANARO

    Energy Technology Data Exchange (ETDEWEB)

    Kim, D. H.; Lee, C. B.; Song, K. W. [Korea Atomic Energy Research Institute, Taejeon (Korea)

    2002-04-01

    This project is preparing to irradiation test of the developed large grain UO{sub 2} fuel pellet in HANARO for pursuit fuel safety and high burn-up in 'Advanced LWR Fuel Technology Development Project' as a part Nuclear Mid and Long-term R and D Program. On the basis test rod is performed the nuclei property and preliminary fuel performance analysis, test rod and non-instrumented capsule are designed and manufactured for irradiation test in HANARO. This non-instrumented irradiation capsule of Advanced PWR Fuel pellet was referred the non-instrumented capsule for an irradiation test of simulated DUPIC fuel in HANARO(DUPIC Rig-001) and 18-element HANARO fuel, was designed to ensure the integrity and the endurance of non-instrumented capsule during the long term(2.5 years) irradiation. To irradiate the UO{sub 2} pellets up to the burn-up 70 MWD/kgU, need the time about 60 months and ensure the integrity of non-instrumented capsule for 30 months until replace the new capsule. This non-instrumented irradiation capsule will be based to develope the non-instrumented capsule for the more long term irradiation in HANARO. 22 refs., 13 figs., 5 tabs. (Author)

  6. Real-time capture and reconstruction system with multiple GPUs for a 3D live scene by a generation from 4K IP images to 8K holograms.

    Science.gov (United States)

    Ichihashi, Yasuyuki; Oi, Ryutaro; Senoh, Takanori; Yamamoto, Kenji; Kurita, Taiichiro

    2012-09-10

    We developed a real-time capture and reconstruction system for three-dimensional (3D) live scenes. In previous research, we used integral photography (IP) to capture 3D images and then generated holograms from the IP images to implement a real-time reconstruction system. In this paper, we use a 4K (3,840 × 2,160) camera to capture IP images and 8K (7,680 × 4,320) liquid crystal display (LCD) panels for the reconstruction of holograms. We investigate two methods for enlarging the 4K images that were captured by integral photography to 8K images. One of the methods increases the number of pixels of each elemental image. The other increases the number of elemental images. In addition, we developed a personal computer (PC) cluster system with graphics processing units (GPUs) for the enlargement of IP images and the generation of holograms from the IP images using fast Fourier transform (FFT). We used the Compute Unified Device Architecture (CUDA) as the development environment for the GPUs. The Fast Fourier transform is performed using the CUFFT (CUDA FFT) library. As a result, we developed an integrated system for performing all processing from the capture to the reconstruction of 3D images by using these components and successfully used this system to reconstruct a 3D live scene at 12 frames per second.

  7. Approche complète de développement des IPs pour les SoCs A ...

    African Journals Online (AJOL)

    CoFluent and Quartus II tools have helped us to get the different models. ... Key words : IPs – SoC - Design and Reuse – UML – System C ... nouvelles techniques de conception doivent- .... obtenir un prototype fabriqué et testé. ..... Information Technology and Control, ... A new logic circuit design methodology with UMLl.

  8. 5 CFR 582.202 - Service of legal process.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Service of legal process. 582.202 Section... GARNISHMENT OF FEDERAL EMPLOYEES' PAY Service of Legal Process § 582.202 Service of legal process. (a) A... agency as a garnishee. (b) Service of legal process may be accomplished by certified or registered mail...

  9. 21 CFR 582.10 - Spices and other natural seasonings and flavorings.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 6 2010-04-01 2010-04-01 false Spices and other natural seasonings and flavorings. 582.10 Section 582.10 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN... General Provisions § 582.10 Spices and other natural seasonings and flavorings. Spices and other natural...

  10. Empirical assessment of VoIP overload detection tests

    NARCIS (Netherlands)

    Żuraniewski, P.; Mandjes, M.; Mellia, M.

    2010-01-01

    The control of communication networks critically relies on procedures capable of detecting unanticipated load changes. In this paper we explore such techniques, in a setting in which each connection consumes roughly the same amount of bandwidth (with VoIP as a leading example). We focus on

  11. Post irradiation examination on test fuel pins for PWR

    International Nuclear Information System (INIS)

    Fogaca Filho, N.; Ambrozio Filho, F.

    1981-01-01

    Certain aspects of irradiation technology on test fuel pins for PWR, are studied. The results of post irradiation tests, performed on test fuel pins in hot cells, are presented. The results of the tests permit an evaluation of the effects of irradiation on the fuel and cladding of the pin. (Author) [pt

  12. In-Pile Section(IPS) Inner Assembly Manufacturing Report

    International Nuclear Information System (INIS)

    Lee, Jong Min; Shim, Bong Sik; Lee, Chung Yong

    2009-12-01

    The objective of this report is to present the manufacturing, assembling and testing process of IPS Inner Assembly used in Fuel Test Loop(FTL) pre-operation test. The majority of the manufactured components are test fuels, inner assembly structures and subsidiary tools that is needed during the assembly process. In addition, Mock-up test for the welding and brazing is included at this stage. Lower structure, such as test fuels, fuel carrier legs are assembled and following structures, such as fuel carrier stem in the middle structure, top flange in the top structure are assembled together each other. To Verify the Reactor Coolant Pressure Boundary(RCPB) function in IPS Inner Assembly helium leak test and hydraulic test is performed with its acceptance criteria. According to the ASME III code Authorized Nuclear Inspector(ANI) is required during the hydraulic test. As-built measurement and insulation resistance test are performed to the structures and instrumentations after the test process. All requirements are satisfied and the IPS Inner Assembly was loaded in HANARO IR-1 hole in September 25, 2009

  13. Effects of piracetam supplementation on cochlear damage occuring in guinea pigs exposed to irradiation

    International Nuclear Information System (INIS)

    Altas, E.; Ertekin, M.V.; Kuduban, O.; Gundogdu, C.; Demirci, E.; Sutbeyaz, Y.

    2006-01-01

    In this study we aimed to determine the role of piracetam (PIR) in preventing radiation induced cochlear damage after total-cranium irradiation (radiotherapy; RT). Male albino guinea pigs used in the study were randomly divided into three groups. Group 1 (Control group) (n=11) received neither PIR nor irradiation, but received saline solution intraperitoneally (i.p.) and received sham irradiation. Group 2 (RT group) (n=32) was exposed to total cranium irradiation of 33 Gy in 5 fractions of 6.6 Gy/d for five successive days, with a calculated (α/β=3.5) biological effective dose of fractionated irradiation equal to 60 Gy conventional fractionation, then received saline solution for five successive days i.p. Group 3 (PIR+RT group) (n=33) received total cranium irradiation, plus 350 mg/kg per day PIR for five successive days i.p. After the last dose of RT, the guinea pigs were all sacrificed at the 4th, 24th and 96th hours, respectively. Their cochleas were enucleated for histopathologic examination. It was observed that total cranium irradiation (RT group) promoted degeneration in stria vascularis (SV), spiral ganglion cells (SG), outer hair cells (OHC) and inner hair cell (IHC) of cochleas at these times (p 0.05) and IHC at 4th, 24th hours (p>0.05), there was a significant difference on radiation-induced cochlear degeneration in SV and OHC at 24th and 96th hours (p<0.05), IHC at 96th hour (p<0.05) and SG at 4th, 24th and 96th hours (p<0.05). There was no any cochlear degeneration in the control group. Piracetam might reduce radiation-induced cochlear damage in the guinea pig. These results are pioneer to studies that will be performed with PIR for radiation toxicity protection. (author)

  14. Minutes of the workshop on bases of in-pile irradiation tests

    International Nuclear Information System (INIS)

    1997-03-01

    The Workshop on Bases of In-pile Irradiation Tests was held on January 29th and 30th, 1997 at the Ibarakiken Sangyo Kaikan in Mito, Ibaraki. The purpose is to discuss upgrading an in-pile irradiation test, promoting the utilization of the research and testing reactors and also activating the research potential of JAERI transversely. Main topics are the role and future plan of the research and testing reactors, a challenge to an advanced irradiation test, development of peripheral techniques for irradiation tests and future trends of the in-pile irradiation test in the 21st century. It was mainly pointed out that the in-pile irradiation test based on an analytical method using interpolation and extrapolation procedures met a turning point and that the upgrading of the irradiation and testing method should be indispensable for regaining the latest frontiers of an irradiation study using the research and testing reactors. The new concepts were also proposed on the irradiation correlation and modeling for the design of innovative materials. It was also recognized the key issues of the irradiation study in future should be an advanced irradiation testing method which can combine various types of irradiation field and control the irradiation conditions freely. In the next century in which large accelerator or new neutron source competes with research and testing reactors for neutron irradiation tests, themes of research using in-pile irradiation tests will be upgrading of the light water reactor, development of fusion reactor, basic research, biological and medical research, radioisotope production and semiconductors manufacturing, etc. It was also concluded the research and testing reactors will keep their main role in neutron irradiation research in future. This report briefly summarizes the content of 16 presentations and the discussion. The result of the questionnaires on the utilization of research and testing reactors to the participants is also attached. (J.P.N.)

  15. Genotoxicity test of irradiated foods

    International Nuclear Information System (INIS)

    Tanaka, Noriho

    2004-01-01

    Safety tests of radiation irradiated foods started as early as from 1967 in Japan and genotoxicity tests in the Hatano Res. Inst., from 1977. The latter is unique in the world and is reviewed in this paper. Tests included those for the initial injury of DNA, mutagenicity, chromosomal aberration and transformation with use of bacteria, cultured mammalian cells and animals (for chromosomal aberration, micronucleus formation and dominant lethality). Foods tested hitherto were onion, rice, wheat and flour, Vienna sausage, fish sausage (kamaboko), mandarian orange, potato, black pepper and red capsicum, of which extract or powder was subjected to the test. Irradiation doses and its purposes were 0.15-6 kGy γ-ray ( 60 Co) or electron beam by the accelerator (only for the orange), and suppression of germination, pesticide action or sterilization, respectively. Genotoxicity of all foods under tested conditions is shown negative. (N.I.)

  16. Studies on potato irradiation in the G.D.R

    International Nuclear Information System (INIS)

    Luther, Th.; Huebner, G.; Grahn, Ch.; Doellstaedt, R.

    1990-01-01

    The studies of potato irradiation have been conducted in the framework of the National Food Irradiation Research Project for 4 years. Although in the G.D.R. the use of chemical sprout inhibitors is allowed, potato irradiation can be an alternative technique for potato processing. Before irradiation a wound healing period of approx. 2 weeks is absolutely necessary to protect the potatoes from Fusarium. The method that presents the minimum risk of damage is irradiation in containers. Economic evaluations for the irradiation of potatoes are also made. (author)

  17. Comparison of the Aerospace Systems Test Reactor loss-of-coolant test data with predictions of the 3D-AIRLOCA code

    International Nuclear Information System (INIS)

    Warinner, D.K.

    1983-01-01

    This paper compares the predictions of the revised 3D-AIRLOCA computer code to those data available from the Aerospace Systems Test Reactor's (ASTR's) loss-of-coolant-accident (LOCA) tests run in 1964. The theoretical and experimental hot-spot temperature responses compare remarkably well. In the thirteen cases studied, the irradiation powers varied from 0.4 to 8.87 MW; the irradiation times were 300, 1540, 1800, and 10 4 s. The degrees of agreement between the data and predictions provide an experimental validation of the 3D-AIRLOCA code

  18. Comparison of the aerospace systems test reactor loss-of-coolant test data with predictions of the 3D-AIRLOCA code

    International Nuclear Information System (INIS)

    Warinner, D.K.

    1984-01-01

    This paper compares the predictions of the revised 3D-AIRLOCA computer code to those data available from the Aerospace Systems Test Reactor's (ASTR's) loss-of-coolant-accident (LOCA) tests run in 1964. The theoretical and experimental hot-spot temperature responses compare remarkably well. In the thirteen cases studied, the irradiation powers varied from 0.4 to 8.87 MW; the irradiation times were 300, 1540, 1800, and 10 4 s. The degrees of agreement between the data and predictions provide an experimental validation of the 3D-AIRLOCA code. (author)

  19. General views about specimen irradiations in reactors; Considerations generales sur'les irradiations d'echantillons dans les reacteurs

    Energy Technology Data Exchange (ETDEWEB)

    Seguin, M [Commissariat a l' Energie Atomique, Grenoble (France). Centre d' Etudes Nucleaires

    1965-07-01

    Specimen irradiation of fissile or non-fissile materials, carried out under circumstances becoming more and more severe and in reactor of increasing flux bas led to an evolution of irradiation rigs. A survey of the problems arising from irradiating under these various circumstances leads to conclude that it is possible to devise one capsule type suitable to every particular case, and that in a wide temperature range. Consequently, once the various irradiation-parameters known, a general method of calculation can be followed so as to determine the various sizes of the parts constituting the capsule. These theoretical calculations might sometimes be corrected through benefits gained from previous irradiations. Similarly, practical experimentation might allow to foresee more handy assembling of the capsule, specimen loading-and unloading being easier at the same time. (author) [French] L'irradiation d'echantillons, fissiles ou non fissiles, dans des conditions imposees de plus en plus strictes et dans des reacteurs a flux de plus en plus eleve, a eu pour consequence une evolution dans la conception des dispositifs d'irradiation. Lorsqu'on examine les problemes souleves par ces differentes irradiations, on en conclut qu'il est possible de concevoir un type de capsule capable de donner satisfaction dans chaque cas particulier, et ce, dans une tres large gamme de temperature. Par consequent, les differents parametres de l'irradiation etant connus, une methode generale de calcul peut etre suivie pour determiner les differentes cotes des pieces constitutives de la capsule. Ces calculs theoriques devront quelquefois etre corriges grace aux enseignements tires d'irradiations precedentes. De meme, l'experience acquise permettra d'envisager un montage plus aise de la capsule, tout en facilitant l'enfournement et le defournement des echantillons.

  20. Irradiation and beam tests qualification for ATLAS IBL Pixel Modules

    International Nuclear Information System (INIS)

    Rubinskiy, Igor

    2013-01-01

    The upgrade for the ATLAS detector will have different steps towards HL-LHC. The first upgrade for the Pixel Detector will consist in the construction of a new pixel layer which will be installed during the first shutdown of the LHC machine (foreseen for 2013–2014). The new detector, called Insertable B-Layer (IBL), will be inserted between the existing Pixel Detector and a new (smaller radius) beam-pipe at a radius of 33 mm. The IBL will require the development of several new technologies to cope with the increase in the radiation damage and the pixel occupancy and also to improve the physics performance, which will be achieved by reduction of the pixel size and of the material budget. Two different promising silicon sensor technologies (Planar n-in-n and 3D) are currently under investigation for the Pixel Detector. An overview of the sensor technologies' qualification with particular emphasis on irradiation and beam tests is presented. -- Highlights: ► The ATLAS inner tracker will be extended with a so called Insertable B-Layer (IBL). ► The IBL modules are required to withstand irradiation up to 5×10 15 n eq /cm 2 . ► Two types of silicon pixel detector technologies (Planar and 3D) were tested in beam. ► The irradiated sensor efficiency exceeds 97% both with and without magnetic field. ► The leakage current, power dissipation, module active area ratio requirements are met.

  1. Biphasic insulin-releasing effect of BTS 67 582 in rats.

    Science.gov (United States)

    Storey, D A; Bailey, C J

    1998-12-01

    BTS 67 582 (1,1-dimethyl-2(2-morpholinophenyl)guanidine fumarate) is being developed as a short-acting anti-diabetic insulin secretagogue. The effect of BTS 67 582 on the phasic pattern of insulin release was assessed in anaesthetized normal rats by measuring arterial plasma insulin concentrations while arterial glucose concentrations were fixed at 6, 8.5 and 12.5 mM. Intravenous BTS 67 582 (10 mg kg(-1)) induced an immediate but transient increase in insulin concentrations which declined by 10 min (first phase). This was followed by a smaller but sustained increase in insulin concentrations (second phase). The increment from basal to peak insulin release (0-2 min) was independent of glucose, but the first phase was maintained for longer and the second phase was greater at the highest concentration of glucose (12.5 mM). BTS 67 582 also extended the first-phase insulin response to a standard intravenous glucose challenge and enhanced the rate of glucose disappearance by approximately 12%. Thus BTS 67 582 causes biphasic stimulation of insulin release and augments the insulin-releasing effect of glucose.

  2. Involvement of N-methyl-d-aspartate receptors in the antidepressant-like effect of 5-hydroxytryptamine 3 antagonists in mouse forced swimming test and tail suspension test.

    Science.gov (United States)

    Kordjazy, Nastaran; Haj-Mirzaian, Arya; Amiri, Shayan; Ostadhadi, Sattar; Amini-Khoei, Hossein; Dehpour, Ahmad Reza

    2016-02-01

    Recent evidence indicates that 5-hydroxytryptamine 3 (5-HT3) antagonists such as ondansetron and tropisetron exert positive behavioral effects in animal models of depression. Due to the ionotropic nature of 5-HT3 and N-methyl-d-aspartate (NMDA) receptors, plus their contribution to the pathophysiology of depression, we investigated the possible role of NMDA receptors in the antidepressant-like effect of 5-HT3 receptor antagonists in male mice. In order to evaluate the animals' behavior in response to different treatments, we performed open-field test (OFT), forced swimming test (FST), and tail-suspension test (TST), which are considered as valid tasks for measuring locomotor activity and depressive-like behaviors in mice. Our data revealed that intraperitoneal (i.p.) administration of tropisetron (5, 10, and 30mg/kg) and ondansetron (0.01, and 0.1μg/kg) significantly decreased the immobility time in FST and TST. Also, co-administration of subeffective doses of tropisetron (1mg/kg, i.p.) or ondansetron (0.001μg/kg, i.p.) with subeffective doses of NMDA receptor antagonists, ketamine (1mg/kg, i.p.), MK-801 (0.05mg/kg, i.p.) and magnesium sulfate (10mg/kg, i.p.) resulted in a reduced immobility time both in FST and TST. The subeffective dose of NMDA (NMDA receptor agonist, 75mg/kg, i.p.) abolished the effects of 5-HT3 antagonists in FST and TST, further supporting the presumed interaction between 5-HT3 and NMDA receptors. These treatments did not affect the locomotor behavior of animals in OFT. Finally, the results of our study suggest that the positive effects of 5-HT3 antagonists on the coping behavior of mice in FST and TST are at least partly mediated through NMDA receptors participation. Copyright © 2015 Elsevier Inc. All rights reserved.

  3. The Worldwide Interplanetary Scintillation (IPS) Stations (WIPSS) Network October 2016 Observing Campaign: Initial WIPSS Data Analyses

    Science.gov (United States)

    Bisi, M. M.; Fallows, R. A.; Jackson, B. V.; Tokumaru, M.; Gonzalez-Esparza, A.; Morgan, J.; Chashei, I. V.; Mejia-Ambriz, J.; Tyul'bashev, S. A.; Manoharan, P. K.; De la Luz, V.; Aguilar-Rodriguez, E.; Yu, H. S.; Barnes, D.; Chang, O.; Odstrcil, D.; Fujiki, K.; Shishov, V.

    2017-12-01

    Interplanetary Scintillation (IPS) allows for the determination of velocity and a proxy for plasma density to be made throughout the corona and inner heliosphere. Where sufficient observations are undertaken, the results can be used as input to the University of California, San Diego (UCSD) three-dimensional (3-D) time-dependent tomography suite to allow for the full 3-D reconstruction of both velocity and density throughout the inner heliosphere. By combining IPS results from multiple observing locations around the planet, we can increase both the temporal and spatial coverage across the whole of the inner heliosphere and hence improve forecast capability. During October 2016, a unique opportunity arose whereby the European-based LOw Frequency ARray (LOFAR) radio telescope was used to make nearly four weeks of continuous observations of IPS as a heliospheric space-weather trial campaign. This was expanded into a global effort to include observations of IPS from the Murchison Widefield Array (MWA) in Western Australia and many more observations from various IPS-dedicated WIPSS Network systems. LOFAR is a next-generation low-frequency radio interferometer capable of observing in the radio frequency range 10-250 MHz, nominally with up to 80 MHz bandwidth at a time. MWA in Western Australia is capable of observing in the 80-300 MHz frequency range nominally using up to 32 MHz of bandwidth. IPS data from LOFAR, ISEE, the MEXican Array Radio Telescope (MEXART), and, where possible, other WIPSS Network systems (such as LPI-BSA and Ooty), will be used in this study and we will present some initial findings for these data sets. We also make a first attempt at the 3-D reconstruction of multiple pertinent WIPSS results in the UCSD tomography. We will also try to highlight some of the potential future tools that make LOFAR a very unique system to be able to test and validate a whole plethora of IPS analysis methods with the same set of IPS data.

  4. Design and Testing for a New Thermosyphon Irradiation Vehicle

    Energy Technology Data Exchange (ETDEWEB)

    Felde, David K. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Carbajo, Juan J. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); McDuffee, Joel Lee [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2017-09-01

    of 10 tests were performed at subatmospheric pressure, and four of these were performed with pure steam. One test was conducted at a high power of 92.7 kW, six tests were HFIR startups, and two tests were HFIR loss of offsite power (LOOP). Pressures up to 10 MPa, vapor temperatures up to 583 K (310°C), and heater temperatures above 600 K (327°C) have been reached in these tests. Two computer programs, RELAP5-3D and TRACE, have been used to simulate the tests. The TRACE code has shown good agreement with the test data and has been used to model a variety of tests. This experimental facility has been very useful in demonstrating the viability of this new type of irradiation facility.

  5. Localitzador Gràfic de Direccions IP 'IpLocInspector'

    OpenAIRE

    Ordóñez Chapado, Miguel

    2006-01-01

    En aquest treball s'ha desenvolupat una aplicació capaç de localitzar adreces IP. En este trabajo se ha desarrollado una aplicación capaz de localizar direcciones IP. In this work an application was developed capable of locating IP addresses.

  6. Machinability of IPS Empress 2 framework ceramic.

    Science.gov (United States)

    Schmidt, C; Weigl, P

    2000-01-01

    Using ceramic materials for an automatic production of ceramic dentures by CAD/CAM is a challenge, because many technological, medical, and optical demands must be considered. The IPS Empress 2 framework ceramic meets most of them. This study shows the possibilities for machining this ceramic with economical parameters. The long life-time requirement for ceramic dentures requires a ductile machined surface to avoid the well-known subsurface damages of brittle materials caused by machining. Slow and rapid damage propagation begins at break outs and cracks, and limits life-time significantly. Therefore, ductile machined surfaces are an important demand for machine dental ceramics. The machining tests were performed with various parameters such as tool grain size and feed speed. Denture ceramics were machined by jig grinding on a 5-axis CNC milling machine (Maho HGF 500) with a high-speed spindle up to 120,000 rpm. The results of the wear test indicate low tool wear. With one tool, you can machine eight occlusal surfaces including roughing and finishing. One occlusal surface takes about 60 min machining time. Recommended parameters for roughing are middle diamond grain size (D107), cutting speed v(c) = 4.7 m/s, feed speed v(ft) = 1000 mm/min, depth of cut a(e) = 0.06 mm, width of contact a(p) = 0.8 mm, and for finishing ultra fine diamond grain size (D46), cutting speed v(c) = 4.7 m/s, feed speed v(ft) = 100 mm/min, depth of cut a(e) = 0.02 mm, width of contact a(p) = 0.8 mm. The results of the machining tests give a reference for using IPS Empress(R) 2 framework ceramic in CAD/CAM systems. Copyright 2000 John Wiley & Sons, Inc.

  7. Answers to the questions about food irradiation. Concerning results of animal experiments in the specified integrated research. Data carrying a problem in human health were obtained?

    International Nuclear Information System (INIS)

    Ito, Hitoshi

    2007-01-01

    Experts of Food and Agriculture Organization (FAO)/ International Atomic Energy Agency (IAEA)/ World Health Organization (WHO) committee obtained their conclusion in 1980 that food irradiated with <10 kGy of radiation is safe for human health, which is now globally approved. However, in Japan, there have been still opposite opinions based on the doubt in the title on the safety of irradiated food. In this paper, the author answers those questions as he was a member to arrange the Research in the title for food irradiation. Described are data presentation and explanation about results of toxicity studies of diets added with irradiated materials of: weight reductions in rat ovary by irradiated potato (ip) in chronic studies, and in mouse testicle and ovary of F3 generation from the ancestor mice kept on diet with irradiated onion (io); bone malformation in mice by io; and reduction of body weight gain in female rats by ip and increase of mortality of male rats by ip. These are analyzed on the aspects of radiation dose-response, sustained tendency of results throughout the living period or generation, and apparent abnormality by other factors; and normal variation due to individual difference is pointed out to contribute to these findings. The safety test of irradiated food has been conducted valid not only in animal experiments but also other tests like genotoxicity and analysis of radiation-degraded products. (R.T.)

  8. Process of radiation damage in BaFX:Eu2+ (X=Br, I) photo-stimulable phosphor for imaging plate (IP)

    International Nuclear Information System (INIS)

    Kato, Munetaka; Takahashi, Kenji

    2005-01-01

    Imaging Plate (IP) is a 2-dimensional radiation detector utilizing photo-stimulable phosphors. Photo-stimulated luminescence (PSL) is a kind of process in radiation-induced reactions and IP can be repeatedly performed. The mechanism of PSL is reviewed and the radiation damage, which is a phenomenon that the luminescence goes down under X-ray irradiation, is also referred to. The relation between the composition of BaFX: Eu 2+ (X=Br, I), which is widely used in IPs, and the degree of radiation damage is investigated. The degree of radiation damage is smaller in the mixed crystal system of Br and I such as BaFBr 0.85 I 0.15 :Eu 2+ than in BaFBr: Eu 2+ and BaFI: Eu 2+ . This is explained by the characteristics of luminescence centers and F centers under X-ray irradiation. (author)

  9. Irradiation Testing of TRISO-Coated Particle Fuel in Korea

    International Nuclear Information System (INIS)

    Kim, Bong Goo; Yeo, Sunghwan; Jeong, Kyung-Chai; Eom, Sung-Ho; Kim, Yeon-Ku; Kim, Woong Ki; Lee, Young Woo; Cho, Moon Sung; Kim, Yong Wan

    2014-01-01

    In Korea, coated particle fuel is being developed to support development of a VHTR. At the end of March 2014, the first irradiation test in HANARO at KAERI to demonstrate and qualify TRISO-coated particle fuel for use in a VHTR was terminated. This experiment was conducted in an inert gas atmosphere without on-line temperature monitoring and control, or on-line fission product monitoring of the sweep gas. The irradiation device contained two test rods, one has nine fuel compacts and the other five compacts and eight graphite specimens. Each compact contains about 260 TRISO-coated particles. The duration of irradiation testing at HANARO was about 135 full power days from last August 2013. The maximum average power per particle was about 165 mW/particle. The calculated peak burnup of the TRISO-coated fuel was a little less than 4 atom percent. Post-irradiation examination is being carried out at KAERI’s Irradiated Material Examination Facility beginning in September of 2014. This paper describes characteristics of coated particle fuel, the design of the test rod and irradiation device for this coated particle fuel, and discusses the technical results of irradiation testing at HANARO. (author)

  10. The development of a pilot industrial irradiation facility; Realisation d'une station d'irradiation {gamma} a caractere 'semi-industriel'

    Energy Technology Data Exchange (ETDEWEB)

    Balestic, F; Leveque, P; Prevost, C; Comte, G [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1958-07-01

    Saclay, utilisee pour le stockage des barres d'uranium apres leur defournement, a ete specialement amenagee pour permettre des irradiations sur des quantites semi-industrielles de produits chimiques et alimentaires. Des calculs de flux {gamma} ont montre qu'il etait possible de realiser des sources intenses et d'irradier de grands volumes avec des arrangements particuliers de barres dans la casemate. L'installation comporte ainsi deux parties ou different la repartition des barres et les dispositifs d'irradiation. Dans une premiere chambre betonnee et climatisee, 9 rangees verticales de barres d'uranium et de canaux a irradiation alternent avec un ecartement minimum de fa n a constituer un assemblage compact. Le diametre des canaux varie de 10 a 20 cm et la hauteur de chargement utile, 70 cm, correspond a la zone sensiblement uniforme du rayonnement. Dans une deuxieme chambre maintenue a -7 deg. C, des balancelles (h: 70 cm, Q: 35 cm) guidees par un monorail circulent autour d'une seule rangee de 20 barres. La carte des flux y a l'interieur de la casemate a ete etablie par une methode de calcul deja utilisee pour les barres de la pile EL2 a Saclay. Le champ du rayonnement varie dans le temps principalement au cours des premiers mois apres le defournement et suivant le motif geo etrique adopte pour les barres. Les intensites d onisation theoriques sont comprises entre dix mille et plusieurs millions de roentgens par heure. Ces valeurs sont comparees aux resultats obtenus avec les dosimetres chimiques au sulfate ferreux et a l'acide oxalique. En outre, des verreseurs etalonnes avec des sources de cobalt permettent un controle rapide de la dose delivree aux balancelles du convoyeur durant leur parcours dans la chambre froide. La casemate de desactivation de EL3 constitue de par sa capacite de traitement la premiere realisation en France d'une station d'irradiation {gamma} a caractere semi-industriel effectuee avec le concours des services du Commissariat a l

  11. Induced desensitization of the insulinotropic effects of antidiabetic drugs, BTS 67 582 and tolbutamide.

    Science.gov (United States)

    McClenaghan, N H; Ball, A J; Flatt, P R

    2000-05-01

    Acute and chronic mechanisms of action of novel insulinotropic antidiabetic drug, BTS 67 582 (1, 1-dimethyl-2-(2-morpholinophenyl)guanidine fumarate), were examined in the stable cultured BRIN-BD11 cell line. BTS 67 582 (100 - 400 microM) stimulated a concentration-dependent increase (PBTS 67 582 in culture time-dependently decreased subsequent responsiveness to acute challenge with 200 microM BTS 67 582 or 200 microM tolbutamide at 12 - 18 h (PBTS 67 582 and tolbutamide. Culture with 100 microM BTS 67 582 or 100 microM tolbutamide did not affect basal insulin secretion, cellular insulin content, or cell viability and exerted no influence on the secretory responsiveness to 200 microM of the imidazoline, efaroxan. While 18 h BTS 67 582 culture did not affect the insulin-releasing actions (PBTS 67 582 shares a common signalling pathway to sulphonylurea but not imidazoline drugs. Desensitization of drug action may provide an important approach to dissect sites of action of novel and established insulinotropic antidiabetic agents.

  12. The insulation irradiation test program for the Compact Ignition Tokamak

    International Nuclear Information System (INIS)

    McManamy, T.J.; Kanemoto, G.; Snook, P.

    1990-01-01

    The electrical insulation for the toroidal field coils of the Compact Ignition Tokamak (CIT) is expected to be exposed to radiation doses on the order of 10 10 rad with ∼90% of the dose from neutrons. The coils are cooled to liquid nitrogen temperature and then heated during the pulse to a peak temperature >300 K. In a program to evaluate the effects of radiation exposure on the insulators, three types of boron-free insulation were irradiated at room temperature in the Advanced Technology Reactor (ATR) and tested at the Idaho National Engineering Laboratory. The materials were Spaulrad-S, Shikishima PG5-1, and Shikishima PG3-1. The first two use a bismaleimide resin and the third an aromatic amine hardened epoxy. Spaulrad-S is a two-dimensional (2-D) weave of S-glass, while the others are 3-D weaves of T-glass. Flexure and shear/compression samples were irradiated to approximately 5 x 10 9 rad and 3 x 10 10 rad with 35 to 40% of the total dose from neutrons. The shear/compression samples were tested in pairs by applying an average compression of 345 MPa and then a shear load. After static tests were completed, fatigue testing was done by cycling the shear load for up to 30,000 cycles with a constant compression. The static shear strength of the samples that did not fail was then determined. Generally, shear strengths on the order of 120 MPa were measured. The behavior of the flexure and shear/compression samples was significantly different; large reductions in the flexure strength were observed, while the shear strength stayed the same or increased slightly. The 3-D weave material demonstrated higher strength and significantly less radiation damage than the 2-D material in flexure but performed nearly identically when tested with combined shear and compression. The epoxy system was much more sensitive to fatigue damage than the bismaleimide materials. 9 refs., 5 figs

  13. Novel characteristics of CtIP at damage-induced foci following the initiation of DNA end resection

    International Nuclear Information System (INIS)

    Fujisawa, Hiroshi; Fujimori, Akira; Okayasu, Ryuichi; Uesaka, Mitsuru; Yajima, Hirohiko

    2015-01-01

    Highlights: • CtIP becomes hyperphosphorylated and forms foci following cell irradiation. • CtIP accumulates in foci subsequent to the peak of hyperphosphorylation. • CtIP is maintained in a hypophosphorylated state at later times. • CtIP is continuously recruited to DNA double strand breaks downstream of resection. • CtIP presumably have a distinct role following the initiation of resection. - Abstract: Homologous recombination (HR) is a major repair pathway for DNA double strand breaks (DSBs), and end resection, which generates a 3′-single strand DNA tail at the DSB, is an early step in the process. Resection is initiated by the Mre11 nuclease together with CtIP. Here, we describe novel characteristics of CtIP at DSBs. At early times following exposure of human cells to ionizing radiation, CtIP localized to the DSB, became hyperphosphorylated and formed foci in an ATM-dependent manner. At later times, when the initiation of resection had occurred, CtIP foci persist but CtIP is maintained in a hypophosphorylated state, which is dependent on ATM and ATR. Exposure to cycloheximide revealed that CtIP turns over at DSB sites downstream of resection. Our findings provide strong evidence that CtIP is continuously recruited to DSBs downstream of both the initiation and extension step of resection, strongly suggesting that CtIP has functions in addition to promoting the initiation of resection during HR

  14. The Advanced Test Reactor Irradiation Facilities and Capabilities

    International Nuclear Information System (INIS)

    S. Blaine Grover; Raymond V. Furstenau

    2007-01-01

    The Advanced Test Reactor (ATR) is one of the world's premiere test reactors for performing long term, high flux, and/or large volume irradiation test programs. The ATR is a very versatile facility with a wide variety of experimental test capabilities for providing the environment needed in an irradiation experiment. These different capabilities include passive sealed capsule experiments, instrumented and/or temperature-controlled experiments, and pressurized water loop experiment facilities. The ATR has enhanced capabilities in experiment monitoring and control systems for instrumented and/or temperature controlled experiments. The control systems utilize feedback from thermocouples in the experiment to provide a custom blended flowing inert gas mixture to control the temperature in the experiments. Monitoring systems have also been utilized on the exhaust gas lines from the experiment to monitor different parameters, such as fission gases for fuel experiments, during irradiation. ATR's unique control system provides axial flux profiles in the experiments, unperturbed by axially positioned control components, throughout each reactor operating cycle and over the duration of test programs requiring many years of irradiation. The ATR irradiation positions vary in diameter from 1.6 cm (0.625 inches) to 12.7 cm (5.0 inches) over an active core length of 122 cm (48.0 inches). Thermal and fast neutron fluxes can be adjusted radially across the core depending on the needs of individual test programs. This paper will discuss the different irradiation capabilities available and the cost/benefit issues related to each capability. Examples of different experiments will also be discussed to demonstrate the use of the capabilities and facilities at ATR for performing irradiation experiments

  15. Tensile and fracture toughness test results of neutron irradiated beryllium

    Energy Technology Data Exchange (ETDEWEB)

    Chaouadi, R.; Moons, F.; Puzzolante, J.L. [Centre d`Etude de l`Energie Nucleaire, Mol (Belgium)

    1998-01-01

    Tensile and fracture toughness test results of four Beryllium grades are reported here. The flow and fracture properties are investigated by using small size tensile and round compact tension specimens. Irradiation was performed at the BR2 material testing reactor which allows various temperature and irradiation conditions. The fast neutron fluence (>1 MeV) ranges between 0.65 and 2.45 10{sup 21} n/cm{sup 2}. In the meantime, un-irradiated specimens were aged at the irradiation temperatures to separate if any the effect of temperature from irradiation damage. Test results are analyzed and discussed, in particular in terms of the effects of material grade, test temperature, thermal ageing and neutron irradiation. (author)

  16. 5 CFR 582.101 - Purpose.

    Science.gov (United States)

    2010-01-01

    ... of the United States Postal Service, the Postal Rate Commission, and the General Accounting Office. ... FEDERAL EMPLOYEES' PAY Purpose, Definitions, and Exclusions § 582.101 Purpose. Section 5520a of title 5 of...

  17. Irradiation testing of coated particle fuel at Hanaro

    International Nuclear Information System (INIS)

    Goo Kim, Bong; Sung Cho, Moo; Kim, Yong Wan

    2014-01-01

    TRISO-coated particle fuel is developing to support development of VHTR in Korea. From August 2013, the first irradiation testing of coated particle fuel was begun to demonstrate and qualify TRISO fuel for use in VHTR in the HANARO at KAERI. This experiment is currently undergoing under the atmosphere of a mixed inert gas without on-line temperature monitoring and control combined with on-line fission product monitoring of the sweep gas. The irradiation device contains two test rods, one contains nine fuel compacts and the other five compacts and eight graphite specimens. Each compact has 263 coated particles. After a peak burn-up of about 4 at% and a peak fast neutron fluence of about 1.7 x 10 21 n/cm 2 , PIE will be carried out at KAERI's Irradiated Material Examination Facility. This paper is described characteristics of coated particle fuel, the design of test rod and irradiation device for coated particle fuel, discusses the technical results for irradiation testing at HANARO. (authors)

  18. Development status of irradiation devices and instrumentation for material and nuclear fuel irradiation tests in HANARO

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Bong Goo; Sohn, Jae Min; Choo, Kee Nam [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2010-04-15

    The High flux Advanced Neutron Application ReactOr (HANARO), an open-tank-in-pool type reactor, is one of the multi-purpose research reactors in the world. Since the commencement of HANARO's operations in 1995, a significant number of experimental facilities have been developed and installed at HANARO, and continued efforts to develop more facilities are in progress. Owing to the stable operation of the reactor and its frequent utilization, more experimental facilities are being continuously added to satisfy various fields of study and diverse applications. The irradiation testing equipment for nuclear fuels and materials at HANARO can be classified into capsules and the Fuel Test Loop (FTL). Capsules for irradiation tests of nuclear fuels in HANARO have been developed for use under the dry conditions of the coolant and materials at HANARO and are now successfully utilized to perform irradiation tests. The FTL can be used to conduct irradiation testing of a nuclear fuel under the operating conditions of commercial nuclear power plants. During irradiation tests conducted using these capsules in HANARO, instruments such as the thermocouple, Linear Variable Differential Transformer (LVDT), small heater, Fluence Monitor (F/M) and Self-Powered Neutron Detector (SPND) are used to measure various characteristics of the nuclear fuel and irradiated material. This paper describes not only the status of HANARO and the status and perspective of irradiation devices and instrumentation for carrying out nuclear fuel and material tests in HANARO but also some results from instrumentation during irradiation tests

  19. Germination test for identification of gamma-irradiated bean seeds

    International Nuclear Information System (INIS)

    Wesolowska, B.; Ignatowicz, S.

    1993-01-01

    The feasibility of germination test for the practical detection of irradiated beans has not been investigated. The objective of this study was to determine if the relationship between the root growth rate and radiation dose could be used to produce a rapid analytical method for identification of irradiated beans. Such detection method could be potentially used for both (a) identification of irradiated food, and (b) for quarantine inspection (to certify that the agricultural product has been irradiated, and the pests present in it do not pose a quarantine risk). Results presented in this paper indicate that the germination test is not always capable of discriminating satisfactorily between irradiated and unirradiated samples of bean seeds, because the sensitivity of the test is often higher than the low doses which are suggested for disinfestation purposes. However, using the germination test, an unexperienced person can easily discriminate untreated bean seeds from those irradiated with 0.3-1.5 kGy doses of gamma radiation. (orig./vhe)

  20. Irradiation tests on bitumen and bitumen coated materials; Essais d'irradiation de bitume et d'enrobes bitumineux

    Energy Technology Data Exchange (ETDEWEB)

    Tabardel-Brian, R.; Rodier, J.; Lefillatre, G. [Commissariat a l' Energie Atomique, Chusclan (France). Centre de Production de Plutonium de Marcoule

    1969-07-01

    The use of bitumen as a material for coating high-activity products calls for prior study of the resistance of bitumen to irradiation. After giving briefly the methods of preparation of bitumen- coated products, this report lists the equipment which has been used for carrying out the {beta} and {gamma} irradiations of these products, and gives the analytical results obtained as a function of the dose rates chosen and of the total integrated dose. Finally, some conclusions have been drawn concerning the best types of bitumen. It should be stressed that some bitumens apparently underwent no degradation whatsoever nor any volume increase, for a total integrated dose of 1.8 x 10{sup 10} rads. (authors) [French] Dans le cadre de l'enrobage par le bitume des produits de haute activite, il est necessaire de verifier au prealable, la tenue du bitume a l'irradiation. Apres un bref rappel de la preparation des enrobes bitumineux, le present rapport regroupe les moyens qui ont ete mis en oeuvre, pour effectuer leurs irradiations sous rayonnement {beta} et sous rayonnement {gamma}, ainsi que les resultats des analyses qui ont ete faites en fonction des debits de doses choisis et de la dose totale integree. Enfin, des conclusions ont ete tirees sur les types de bitume a retenir. On peut souligner que certains bitumes n'ont subi aucune degradation apparente ni augmentation de volume pour une dose totale integree de 1.8 x 10{sup 10} rads. (auteurs)

  1. Evaluation of fuel rods behavior - under irradiation test

    International Nuclear Information System (INIS)

    Lameiras, F.S.; Terra, J.L.; Pinto, L.C.M.; Dias, M.S.; Pinheiro, R.B.

    1981-04-01

    By the accompanying of the irradiation of instrumented test fuel rods simulating the operational conditions in reactors, plus the results of post - irradiation exams, tests, evaluation and calibration of analitic modelling of such fuel rods is done. (E.G.) [pt

  2. Spojení s dynamickou IP adresou

    Czech Academy of Sciences Publication Activity Database

    Papík, Martin; Hodboď, J.

    2013-01-01

    Roč. 47, č. 2 (2013), s. 60-61 ISSN 1211-0906 R&D Projects: GA ČR GA13-02149S Institutional support: RVO:67985556 Keywords : dynamical IP adress * dynamic DNS * web services Subject RIV: JC - Computer Hardware ; Software

  3. Stress corrosion testing of irradiated cladding tubes

    International Nuclear Information System (INIS)

    Lunde, L.; Olshausen, K.D.

    1980-01-01

    Samples from two fuel rods with different cladding have been stress corrosion tested by closed-end argon-iodine pressurization at 320 0 C. The fuel rods with stress relieved and recrystallized Zircaloy-2 had received burnups of 10.000 and 20.000 MWd/ton UO 2 , respectively. It was found that the SCC failure stress was unchanged or slightly higher for the irradiated than for the unirradiated control tubes. The tubes failed consistently in the end with the lowest irradiation dose. The diameter increase of the irradiated cladding during the test was 1.1% for the stress-relieved samples and 0.24% for the recrystallized samples. SEM examination revealed no major differences between irradiated and unirradiated cladding. A ''semi-ductile'' fracture zone in recrystallized material is described in some detail. (author)

  4. Study on sensory test of irradiated spices

    International Nuclear Information System (INIS)

    Chiba, Etsuko; Iizuka, Tomoko; Ichikawa, Mariko; Kobayashi, Yasuhiko; Ukai, Mitsuko; Kikuchi, Masahiro

    2016-01-01

    For the spices used in curry dishes and the spices used except for curry dishes, the effects of irradiation sterilization and conventional superheated-steam sterilization were compared with sensory test. As for spices, superheated-steam sterilization reduces aroma and changes color tone compared with irradiation sterilization. Even with cooked curry, radiologically sterilized products were stronger in 'flavor before sample tasting' or 'spicy taste during sample tasting' with statistically significant difference compared with superheated-steam sterilized products. As for the comparison with spices themselves, red pepper and white/black pepper tended to be stronger in taste and pungent taste than radiologically sterilized products. In addition, superheated-steam sterilized products of red hot pepper and turmeric were very different in color from untreated products, while radiologically sterilized products showed a little difference. When comparing color and flavor in a 2D map, it was found at a glance that the radiologically sterilized product was close to the untreated product. Thia map can easily convince the merit of irradiation sterilization, and it was found to be effective for promoting risk communication. In the case of white pepper, the radiologically sterilized product showed more strong pungent than the superheated-steam sterilized product with statistically significant difference. However, not only the strength difference but also qualitative difference was perceived in flavor. (A.O.)

  5. Continuously Connected With Mobile IP

    Science.gov (United States)

    2002-01-01

    Cisco Systems developed Cisco Mobile Networks, making IP devices mobile. With this innovation, a Cisco router and its connected IP devices can roam across network boundaries and connection types. Because a mobile user is able to keep the same IP address while roaming, a live IP connection can be maintained without interruption. Glenn Research Center jointly tested the technology with Cisco, and is working to use it on low-earth-orbiting research craft. With Cisco's Mobile Networks functionality now available in Cisco IOS Software release 12.2(4)T, the commercial advantages and benefits are numerous. The technology can be applied to public safety, military/homeland security, emergency management services, railroad and shipping systems, and the automotive industry. It will allow ambulances, police, firemen, and the U.S. Coast Guard to stay connected to their networks while on the move. In the wireless battlefield, the technology will provide rapid infrastructure deployment for U.S. national defense. Airline, train, and cruise passengers utilizing Cisco Mobile Networks can fly all around the world with a continuous Internet connection. Cisco IOS(R) Software is a registered trademark of Cisco Systems.

  6. Design, fabrication and installation of irradiation facilities

    International Nuclear Information System (INIS)

    Kim, Yong Sung; Lee, C. Y.; Kim, J. Y.; Chi, D. Y.; Kim, S. H.; Ahn, S. H.; Kim, S. J.; Kim, J. K.; Yang, S. H.; Yang, S. Y.; Kim, H. R.; Kim, H.; Lee, K. H.; Lee, B. C.; Park, C.; Lee, C. T.; Cho, S. W.; Kwak, K. K.; Suk, H. C.

    1997-07-01

    The principle contents of this project are to design, fabricate and install the steady-state fuel test loop and non-instrumented capsule in HANARO for nuclear technology development. This project will be completed in 1999, the basic and detail design, safety analysis, and procurement of main equipment for fuel test loop have been performed and also the piping in gallery and the support for IPS piping in reactor pool have been installed in 1994. In the area of non-instrumented capsule for material irradiation test, the fabrication of capsule has been completed. Procurement, fabrication and installation of the fuel test loop will be implemented continuously till 1999. As besides, as these irradiation facilities will be installed in HANARO, review of safety concern, discussion with KINS for licensing and safety analysis report has been submitted to KINS to get a license and review of HANARO interface have been performed respectively. (author). 39 refs., 28 tabs., 21 figs

  7. Design, fabrication and installation of irradiation facilities

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Yong Sung; Lee, C. Y.; Kim, J. Y.; Chi, D. Y.; Kim, S. H.; Ahn, S. H.; Kim, S. J.; Kim, J. K.; Yang, S. H.; Yang, S. Y.; Kim, H. R.; Kim, H.; Lee, K. H.; Lee, B. C.; Park, C.; Lee, C. T.; Cho, S. W.; Kwak, K. K.; Suk, H. C. [and others

    1997-07-01

    The principle contents of this project are to design, fabricate and install the steady-state fuel test loop and non-instrumented capsule in HANARO for nuclear technology development. This project will be completed in 1999, the basic and detail design, safety analysis, and procurement of main equipment for fuel test loop have been performed and also the piping in gallery and the support for IPS piping in reactor pool have been installed in 1994. In the area of non-instrumented capsule for material irradiation test, the fabrication of capsule has been completed. Procurement, fabrication and installation of the fuel test loop will be implemented continuously till 1999. As besides, as these irradiation facilities will be installed in HANARO, review of safety concern, discussion with KINS for licensing and safety analysis report has been submitted to KINS to get a license and review of HANARO interface have been performed respectively. (author). 39 refs., 28 tabs., 21 figs.

  8. Pressurisation of IP-SOFC technology for second generation hybrid application

    Energy Technology Data Exchange (ETDEWEB)

    Jones, L.

    2005-07-01

    The Integrated Planar Solid Oxide Fuel Cell (IP-SOFC) technology developed by Rolls-Royce plc is a hybrid fuel cell technology considered highly suitable for the distributed power generation market. This report presents the results of a project to examine the technical viability of the IP-SOFC technology and some of the associated hybrid system component technologies under pressurised conditions and to investigate the validity of the predicted pressurisation phenomena. The work included: identification of critical material specifications, construction processes, control parameters, etc; the design and commissioning of two pressurised IP-SOFC test rigs at Rolls Royce in Derby; testing two multi-bundle strips at high temperature and atmospheric pressure; testing an active IP-SOFC bundle at high temperature and pressure; testing an experimental steam reforming unit at high temperature and pressure; testing a novel low pressure drop, off-gas combustor concept under atmospheric and pressurised conditions; design studies to identify key parameters affecting the successful integration and packaging of the fuel cell stack with certain associated hybrid components; and designing a hybrid system experimental verification rig. Significant progress was made in addressing the development challenges associated with the IP-SOFC of leakage, performance, durability, yield and geometry, the reaction rate of steam reforming and emissions from the off-gas combustor. Recommendations for future work are made.

  9. FFTF utilization for irradiation testing

    International Nuclear Information System (INIS)

    Corrigan, D.C.; Julyk, L.J.; Hoth, C.W.; McGuire, J.C.; Sloan, W.R.

    1980-01-01

    FFTF utilization for irradiation testing is beginning. Two Fuels Open Test Assemblies and one Vibration Open Test Assembly, both containing in-core contact instrumentation, are installed in the reactor. These assemblies will be used to confirm plant design performance predictions. Some 100 additional experiments are currently planned to follow these three. This will result in an average core loading of about 50 test assemblies throughout the early FFTF operating cycles

  10. Total body irradiation with a compensator fabricated using a 3D optical scanner and a 3D printer.

    Science.gov (United States)

    Park, So-Yeon; Kim, Jung-In; Joo, Yoon Ha; Lee, Jung Chan; Park, Jong Min

    2017-05-07

    We propose bilateral total body irradiation (TBI) utilizing a 3D printer and a 3D optical scanner. We acquired surface information of an anthropomorphic phantom with the 3D scanner and fabricated the 3D compensator with the 3D printer, which could continuously compensate for the lateral missing tissue of an entire body from the beam's eye view. To test the system's performance, we measured doses with optically stimulated luminescent dosimeters (OSLDs) as well as EBT3 films with the anthropomorphic phantom during TBI without a compensator, conventional bilateral TBI, and TBI with the 3D compensator (3D TBI). The 3D TBI showed the most uniform dose delivery to the phantom. From the OSLD measurements of the 3D TBI, the deviations between the measured doses and the prescription dose ranged from  -6.7% to 2.4% inside the phantom and from  -2.3% to 0.6% on the phantom's surface. From the EBT3 film measurements, the prescription dose could be delivered to the entire body of the phantom within  ±10% accuracy, except for the chest region, where tissue heterogeneity is extreme. The 3D TBI doses were much more uniform than those of the other irradiation techniques, especially in the anterior-to-posterior direction. The 3D TBI was advantageous, owing to its uniform dose delivery as well as its efficient treatment procedure.

  11. AGR-2 Irradiation Test Final As-Run Report

    Energy Technology Data Exchange (ETDEWEB)

    Collin, Blaise P. [Idaho National Lab. (INL), Idaho Falls, ID (United States). VHTR Program

    2014-08-01

    This document presents the as-run analysis of the AGR-2 irradiation experiment. AGR-2 is the second of the planned irradiations for the Advanced Gas Reactor (AGR) Fuel Development and Qualification Program. Funding for this program is provided by the U.S. Department of Energy as part of the Very High Temperature Reactor (VHTR) Technology Development Office (TDO) program. The objectives of the AGR-2 experiment are to: 1. Irradiate UCO (uranium oxycarbide) and UO2 (uranium dioxide) fuel produced in a large coater. Fuel attributes are based on results obtained from the AGR-1 test and other project activities. 2. Provide irradiated fuel samples for post-irradiation experiment (PIE) and safety testing. 3. Support the development of an understanding of the relationship between fuel fabrication processes, fuel product properties, and irradiation performance. The primary objective of the test was to irradiate both UCO and UO2 TRISO (tristructural isotropic) fuel produced from prototypic scale equipment to obtain normal operation and accident condition fuel performance data. The UCO compacts were subjected to a range of burnups and temperatures typical of anticipated prismatic reactor service conditions in three capsules. The test train also includes compacts containing UO2 particles produced independently by the United States, South Africa, and France in three separate capsules. The range of burnups and temperatures in these capsules were typical of anticipated pebble bed reactor service conditions. The results discussed in this report pertain only to U.S.-produced fuel.

  12. AGR-2 Irradiation Test Final As-Run Report

    Energy Technology Data Exchange (ETDEWEB)

    Collin, Blaise P. [Idaho National Lab. (INL), Idaho Falls, ID (United States). VHTR Program

    2014-08-01

    This document presents the as-run analysis of the AGR-2 irradiation experiment. AGR-2 is the second of the planned irradiations for the Advanced Gas Reactor (AGR) Fuel Development and Qualification Program. Funding for this program is provided by the U.S. Department of Energy as part of the Very High Temperature Reactor (VHTR) Technical Development Office (TDO) program. The objectives of the AGR-2 experiment are to: (a) Irradiate UCO (uranium oxycarbide) and UO2 (uranium dioxide) fuel produced in a large coater. Fuel attributes are based on results obtained from the AGR-1 test and other project activities. (b) Provide irradiated fuel samples for post-irradiation experiment (PIE) and safety testing. (c) Support the development of an understanding of the relationship between fuel fabrication processes, fuel product properties, and irradiation performance. The primary objective of the test was to irradiate both UCO and UO2 TRISO (tri-structural isotropic) fuel produced from prototypic scale equipment to obtain normal operation and accident condition fuel performance data. The UCO compacts were subjected to a range of burnups and temperatures typical of anticipated prismatic reactor service conditions in three capsules. The test train also includes compacts containing UO2 particles produced independently by the United States, South Africa, and France in three separate capsules. The range of burnups and temperatures in these capsules were typical of anticipated pebble bed reactor service conditions. The results discussed in this report pertain only to U.S. produced fuel.

  13. Irradiation testing of high density uranium alloy dispersion fuels

    International Nuclear Information System (INIS)

    Hayes, S.L.; Trybus, C.L.; Meyer, M.K.

    1997-10-01

    Two irradiation test vehicles have been designed, fabricated, and inserted into the Advanced Test Reactor in Idaho. Irradiation of these experiments began in August 1997. These irradiation tests were designed to obtain irradiation performance information on a variety of potential new, high-density dispersion fuels. Each of the two irradiation vehicles contains 32 microplates. Each microplate is aluminum clad, having an aluminum matrix phase and containing one of the following compositions as the fuel phase: U-10Mo, U-8Mo, U-6Mo, U-4Mo, U-9Nb-3Zr, U-6Nb-4Zr, U-5Nb-3Zr, U-6Mo-1Pt, U-6Mo-0.6Ru, U-10Mo-0.05Sn, U 2 Mo, or U 3 Si 2 . These experiments will be discharged at peak fuel burnups of 40% and 80%. Of particular interest is the fission gas retention/swelling characteristics of these new fuel alloys. This paper presents the design of the irradiation vehicles and the irradiation conditions

  14. Conceptual design for simulator of irradiation test reactors

    International Nuclear Information System (INIS)

    Takemoto, Noriyuki; Ohto, Tsutomu; Magome, Hirokatsu; Izumo, Hironobu; Hori, Naohiko

    2012-03-01

    A simulator of irradiation test reactors has been developed since JFY 2010 for understanding reactor behavior and for upskilling in order to utilize a nuclear human resource development (HRD) and to promote partnership with developing countries which have a plan to introduce nuclear power plant. The simulator is designed based on the JMTR, one of the irradiation test reactors, and it simulates operation, irradiation tests and various kinds of accidents caused by the reactor and irradiation facility. The development of the simulator is sponsored by the Japanese government as one of the specialized projects of advanced research infrastructure in order to promote basic as well as applied researches. The training using the simulator will be started for the nuclear HRD from JFY 2012. This report summarizes the result of the conceptual design of the simulator in JFY 2010. (author)

  15. Application of heavy-ion microbeam system at Kyoto University: Energy response for imaging plate by single ion irradiation

    International Nuclear Information System (INIS)

    Tosaki, M.; Nakamura, M.; Hirose, M.; Matsumoto, H.

    2011-01-01

    A heavy-ion microbeam system for cell irradiation has been developed using an accelerator at Kyoto University. We have successfully developed proton-, carbon-, fluorine- and silicon-beams in order to irradiate a micro-meter sized area with ion counting, especially single ion irradiation. In the heavy-ion microbeam system, an imaging plate (IP) was utilized for beam diagnostics on the irradiation. The IP is widely used for radiography studies in biology. However, there are a few studies on the low linear energy transfer (LET) by single ions, i.e., low-intensity exposure. Thus we have investigated the energy response for the IP, which can be utilized for microbeam diagnostics.

  16. Irradiation test of borosilicate glass burnable poison

    International Nuclear Information System (INIS)

    Feng Mingquan; Liao Zumin; Yang Mingjin; Lu Changlong; Huang Deyang; Zeng Wangchun; Zhao Xihou

    1991-08-01

    The irradiation test and post-irradiation examinations for borosilicate glass burnable poison are introduced. Examinations include visual examination, measurement of dimensions and density, and determination of He gas releasing and 10 B burnup. The corrosion and phenomenon of irradiation densification are also discussed. Two type glass samples have been irradiated with different levels of neutron flux. It proved that the GG-17 borosilicate glass can be used as burnable poison to replace the 10 B stainless steel in the Qinshan Nuclear Power Plant, and it is safe, economical and reasonable

  17. Evaluation of IP Portfolios

    DEFF Research Database (Denmark)

    Søberg, Peder Veng

    2009-01-01

    As a result of an inquiry concerning how to evaluate IP (intellectual property) portfolios in order to enable the best possible use of IP resources within organizations, an IP evaluation approach primarily applicable for patents and utility models is developed. The developed approach is useful...... of the organization owning the IP....

  18. Microbiological specifications and testing methods for irradiated food. Report of a panel of experts; Specifications et methodes d'analyse microbiologiques des aliments irradies. Rapport d'un groupe d'etude

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1971-09-01

    In recent years there has been increased interest in the development of food items processed by means of ionizing radiation, wherever that form of preservation might show advantage over other methods. If this method becomes successful, the various items will be commercially exploited; it would then be convenient to have similar legislation in many countries of the world to control this type of processing and to facilitate international trade. To gather information and suggestions in order to devise legislation on irradiated food, a Joint FAO/IAEA/ WHO Expert Committee on the Technical Basis for Legislation on Irradiated Food was held in Rome on 21-28 April 1964. The Committee's report, 'The technical basis for legislation on irradiated food', was published as FAO Atomic Energy Series No.6 and WHO Technical Series No. 316. The Committee's terms of reference were to consider the available evidence on the effect on food of treatment with ionizing radiation in the context of wholesomeness and safety for consumption. Nutritional aspects were taken into account, but microbiological safety and microbiological methods for irradiated food were excluded since these subjects were believed to be too broad for adequate coverage in the working time available at the meeting. However, realizing the importance of radiation microbiology and the need for guidance in formulating regulations in this field, the committee drafted the following recommendation: 'The methods and standards used to ensure the microbiological safety of the irradiated product should, as a matter of urgency, be subject to review by competent international bodies in order that internationally acceptable methods and standards may be agreed upon'. In response to this recommendation an FAO/IAEA Panel on Microbiological Standards and Testing Methods for Irradiated Food was held in Vienna on 22-26 June 1965, in collaboration with the International Association of Microbiological Societies (IAMS). This was a working

  19. Irradiation Testing Vehicles for Fast Reactors from Open Test Assemblies to Closed Loops

    Energy Technology Data Exchange (ETDEWEB)

    Sienicki, James J. [Argonne National Lab. (ANL), Argonne, IL (United States); Grandy, Christopher [Argonne National Lab. (ANL), Argonne, IL (United States)

    2016-12-15

    A review of irradiation testing vehicle approaches and designs that have been incorporated into past Sodium-Cooled Fast Reactors (SFRs) or envisioned for incorporation has been carried out. The objective is to understand the essential features of the approaches and designs so that they can inform test vehicle designs for a future U.S. Fast Test Reactor. Fast test reactor designs examined include EBR-II, FFTF, JOYO, BOR-60, PHÉNIX, JHR, and MBIR. Previous designers exhibited great ingenuity in overcoming design and operational challenges especially when the original reactor plant’s mission changed to an irradiation testing mission as in the EBRII reactor plant. The various irradiation testing vehicles can be categorized as: Uninstrumented open assemblies that fit into core locations; Instrumented open test assemblies that fit into special core locations; Self-contained closed loops; and External closed loops. A special emphasis is devoted to closed loops as they are regarded as a very desirable feature of a future U.S. Fast Test Reactor. Closed loops are an important technology for irradiation of fuels and materials in separate controlled environments. The impact of closed loops on the design of fast reactors is also discussed in this report.

  20. IP-telefon säästab oluliselt sidekulusid / Kristjan Otsmann

    Index Scriptorium Estoniae

    Otsmann, Kristjan, 1971-

    2005-01-01

    Telekomifirma Norby Telecomi poolt pakutavast IP-telefonist ehk helistamisest läbi Interneti, millega saab vähendada sidekulusid mitmeid kordi. Erinevatest internetipõhise kõnesidelahenduse lisateenustest. Vt. samas: Saaremaa Spa Hotellid säästab tuhandeid kroone kuus [intervjuu Saaremaa Spa Hotellide IT-juhiga Andri Võrguga]; Kuus olulist tööd enne IP-lahenduse tellimist

  1. Storage tests on irradiated deep-frozen chickens

    International Nuclear Information System (INIS)

    Gruenewald, T.

    1975-01-01

    Salmonellae infections in deep-frozen roasting chicken can be dealt with by ionising radiation as this process involves hardly any heating of the product. Deep-frozen chickens irradiated with doses up to 800 krad were stored at -30 0 C for two years and were regularly submitted to sensory tests. There was no significant difference in quality between the irradiated samples and the non-irradiated controls. (orig.) [de

  2. Preliminary test results for post irradiation examination on the HTTR fuel

    International Nuclear Information System (INIS)

    Ueta, Shohei; Umeda, Masayuki; Sawa, Kazuhiro; Sozawa, Shizuo; Shimizu, Michio; Ishigaki, Yoshinobu; Obata, Hiroyuki

    2007-01-01

    The future post-irradiation program for the first-loading fuel of the HTTR is scheduled using the HTTR fuel handling facilities and the Hot Laboratory in the Japan Materials Testing Reactor (JMTR) to confirm its irradiation resistance and to obtain data on its irradiation characteristics in the core. This report describes the preliminary test results and the future plan for a post-irradiation examination for the HTTR fuel. In the preliminary test, fuel compacts made with the same SiC-coated fuel particle as the first loading fuel were used. In the preliminary test, dimension, weight, fuel failure fraction, and burnup were measured, and X-ray radiograph, SEM, and EPMA observations were carried out. Finally, it was confirmed that the first-loading fuel of the HTTR showed good quality under an irradiation condition. The future plan for the post-irradiation tests was described to confirm its irradiation performance and to obtain data on its irradiation characteristics in the HTTR core. (author)

  3. Irradiation Testing of Ultrasonic Transducers

    International Nuclear Information System (INIS)

    Daw, J.; Rempe, J.; Palmer, J.; Tittmann, B.; Reinhardt, B.; Kohse, G.; Ramuhalli, P.; Montgomery, R.; Chien, H.T.; Villard, J.F.

    2013-06-01

    Ultrasonic technologies offer the potential for high accuracy and resolution in-pile measurement of numerous parameters, including geometry changes, temperature, crack initiation and growth, gas pressure and composition, and microstructural changes. Many Department of Energy-Office of Nuclear Energy (DOE-NE) programs are exploring the use of ultrasonic technologies to provide enhanced sensors for in-pile instrumentation during irradiation testing. For example, the ability of single, small diameter ultrasonic thermometers (UTs) to provide a temperature profile in candidate metallic and oxide fuel would provide much needed data for validating new fuel performance models. Other efforts include an ultrasonic technique to detect morphology changes (such as crack initiation and growth) and acoustic techniques to evaluate fission gas composition and pressure. These efforts are limited by the lack of existing knowledge of ultrasonic transducer material survivability under irradiation conditions. To address this need, the Pennsylvania State University (PSU) was awarded an Advanced Test Reactor National Scientific User Facility (ATR NSUF) project to evaluate promising magnetostrictive and piezoelectric transducer performance in the Massachusetts Institute of Technology Research Reactor (MITR) up to a fast fluence of at least 10 21 n/cm 2 (E> 0.1 MeV). This test will be an instrumented lead test; and real-time transducer performance data will be collected along with temperature and neutron and gamma flux data. By characterizing magnetostrictive and piezoelectric transducer survivability during irradiation, test results will enable the development of novel radiation tolerant ultrasonic sensors for use in Material and Test Reactors (MTRs). The current work bridges the gap between proven out-of-pile ultrasonic techniques and in-pile deployment of ultrasonic sensors by acquiring the data necessary to demonstrate the performance of ultrasonic transducers. (authors)

  4. Irradiation effects test Series Scoping Test 1: test results report

    International Nuclear Information System (INIS)

    Quapp, W.J.; Allison, C.M.; Farrar, L.C.

    1977-09-01

    The report describes the results of the first scoping test in the Irradiation Effects Test Series conducted by the Thermal Fuels Behavior Program, which is part of the Water Reactor Research Program of EG and G Idaho, Inc. The research is sponsored by the United States Nuclear Regulatory Commission. This test used an unirradiated, three-foot-long, PWR-type fuel rod. The objective of this test was to thoroughly evaluate the remote fabrication procedures to be used for irradiated rods in future tests, handling plans, and reactor operations. Additionally, selected fuel behavior data were obtained. The fuel rod was subjected to a series of preconditioning power cycles followed by a power increase which brought the fuel rod power to about 20.4 kW/ft peak linear heat rating at a coolant mass flux of 1.83 x 10 6 lb/hr-ft 2 . Film boiling occurred for a period of 4.8 minutes following flow reductions to 9.6 x 10 5 and 7.5 x 10 5 lb/hr-ft 2 . The test fuel rod failed following reactor shutdown as a result of heavy internal and external cladding oxidation and embrittlement which occurred during the film boiling operation

  5. Accelerated irradiation test of Gundremmingen reactor vessel trepan material

    Energy Technology Data Exchange (ETDEWEB)

    Hawthorne, J.R. [Materials Engineering Associates, Inc., Lanham, MD (United States)

    1992-08-01

    Initial mechanical properties tests of beltline trepanned from the decommissioned KRB-A pressure vessel and archive material irradiated in the UBR test reactor revealed a major anomaly in relative radiation embrittlement sensitivity. Poor correspondence of material behavior in test vs. power reactor environments was observed for the weak test orientation (ASTL C-L) whereas correspondence was good for the strong orientation (ASTM C-L). To resolve the anomaly directly, Charpy-V specimens from a low (essentially-nil) fluence region of the vessel were irradiated together with archive material at 279{degrees}C in the UBR test reactor. Properties tests before UBR irradiation revealed a significant difference in 41-J transition temperature and upper shelf energy level between the materials. However, the materials exhibited essentially the same radiation embrittlement sensitivity (both orientations), proving that the anomaly is not due to a basic difference in material irradiation resistances. Possible causes of the original anomaly and the significance to NRC Regulatory Guide 1.99 are discussed.

  6. Accelerated irradiation test of gundremmingen reactor vessel trepan material

    International Nuclear Information System (INIS)

    Hawthorne, J.R.

    1992-08-01

    Initial mechanical properties tests of beltline trepanned from the decommissioned KRB-A pressure vessel and archive material irradiated in the UBR test reactor revealed a major anomaly in relative radiation embrittlement sensitivity. Poor correspondence of material behavior in test vs. power reactor environments was observed for the weak test orientation (ASTL C-L) whereas correspondence was good for the strong orientation (ASTM C-L). To resolve the anomaly directly, Charpy-V specimens from a low (essentially-nil) fluence region of the vessel were irradiated together with archive material at 279 degrees C in the UBR test reactor. Properties tests before UBR irradiation revealed a significant difference in 41-J transition temperature and upper shelf energy level between the materials. However, the materials exhibited essentially the same radiation embrittlement sensitivity (both orientations), proving that the anomaly is not due to a basic difference in material irradiation resistances. Possible causes of the original anomaly and the significance to NRC Regulatory Guide 1.99 are discussed

  7. PVM and IP multicast

    Energy Technology Data Exchange (ETDEWEB)

    Dunigan, T.H.; Hall, K.A.

    1996-12-01

    This report describes a 1994 demonstration implementation of PVM that uses IP multicast. PVM`s one-to-many unicast implementation of its pvm{_}mcast() function is replaced with reliable IP multicast. Performance of PVM using IP multicast over local and wide-area networks is measured and compared with the original unicast implementation. Current limitations of IP multicast are noted.

  8. Updated Results of Ultrasonic Transducer Irradiation Test

    Energy Technology Data Exchange (ETDEWEB)

    Daw, Joshua; Palmer, Joe [Idaho National Laboratory, P.O. Box 1625, MS 4112, Idaho Falls, ID, 38415-3840 (United States); Ramuhalli, Pradeep; Keller, Paul; Montgomery, Robert [Pacific Northwest National Laboratory, 902 Battelle Blvd. Richland, WA, 99354 (United States); Chien, Hual-Te [Argonne National Laboratory, 9700 S. Cass Avenue Argonne, IL, 60439 (United States); Tittmann, Bernhard; Reinhardt, Brian [Pennsylvania State University, 212 Earth and Engr. Sciences Building, University Park, PA, 16802 (United States); Kohse, Gordon [Massachusetts Institute of Technology, 77 Massachusetts Ave. Cambridge, MA 02139 (United States); Rempe, Joy [Rempe and Associates, LLC, 360 Stillwater, Idaho Falls, ID 83404 (United States); Villard, J.F. [Commissariat a l' energie atomique et aux energies alternatives, Centre d' etudes de Cadarache, 13108 Saint-Paul-lez-Durance (France)

    2015-07-01

    Ultrasonic technologies offer the potential for high accuracy and resolution in-pile measurement of a range of parameters, including geometry changes, temperature, crack initiation and growth, gas pressure and composition, and microstructural changes. Many Department of Energy-Office of Nuclear Energy (DOE-NE) programs are exploring the use of ultrasonic technologies to provide enhanced sensors for in-pile instrumentation during irradiation testing. For example, the ability of small diameter ultrasonic thermometers (UTs) to provide a temperature profile in candidate metallic and oxide fuel would provide much needed data for validating new fuel performance models. These efforts are limited by the lack of identified ultrasonic transducer materials capable of long term performance under irradiation test conditions. To address this need, the Pennsylvania State University (PSU) was awarded an Advanced Test Reactor National Scientific User Facility (ATR NSUF) project to evaluate the performance of promising magnetostrictive and piezoelectric transducers in the Massachusetts Institute of Technology Research Reactor (MITR) up to a fast fluence of at least 10{sup 21} n/cm{sup 2}. A multi-National Laboratory collaboration funded by the Nuclear Energy Enabling Technologies Advanced Sensors and Instrumentation (NEET-ASI) program also provided initial support for this effort. This irradiation, which started in February 2014, is an instrumented lead test and real-time transducer performance data are collected along with temperature and neutron and gamma flux data. The irradiation is ongoing and will continue to approximately mid-2015. To date, very encouraging results have been attained as several transducers continue to operate under irradiation. (authors)

  9. Ceramic (Feldspathic & IPS Empress II) vs. laboratory composite (Gradia) veneers; a comparison between their shear bond strength to enamel; an in vitro study.

    Science.gov (United States)

    Nikzad, S; Azari, Abbas; Dehgan, S

    2010-07-01

    Patient demand for aesthetic dentistry is steadily growing. Laminates and free metal restorations have evolved in an attempt to overcome the invasiveness nature of full veneer restorations. Although many different materials have been used for making these restorations, there is no single material that fits best for all purposes. Two groups of ceramic material (Feldspathic and IPS Empress II) and one group of laboratory composite (Gradia) discs (10 discs in each group; 4 mm in diameter and 2 mm in thickness) were prepared according to the manufacturer's instruction. The surface of ceramic discs were etched and silanized. In Gradia group, liquid primer was applied on composite surfaces. Thirty freshly extracted sound human molars and premolars were randomly divided into three groups. The enamel surface of each tooth was slightly flattened (0.3 mm) on the buccal or lingual side and then primed and cemented to the prepared discs with the aid of a dental surveyor. The finishing specimens were thermocycled between 5 degrees C and 55 degrees C for 2500 cycles and then prepared for shear bond strength testing. The resulting data were analyzed by one-way anova and Tukey HSD test. The fractured surfaces of each specimen were inspected by means of stereomicroscope and SEM. There is significant difference between the bond strength of materials tested. The mean bond strengths obtained with Feldspathic ceramic, IPS Empress II and Gradia were 33.10 +/- 4.31 MPa, 26.04 +/- 7.61 MPa and 14.42 +/- 5.82 MPa, respectively. The fracture pattern was mainly mixed for ceramic groups. More scientific evidence needed for standardization of bonding protocols.

  10. Induced desensitization of the insulinotropic effects of antidiabetic drugs, BTS 67 582 and tolbutamide

    Science.gov (United States)

    McClenaghan, Neville H; Ball, Andrew J; Flatt, Peter R

    2000-01-01

    Acute and chronic mechanisms of action of novel insulinotropic antidiabetic drug, BTS 67 582 (1,1-dimethyl-2-(2-morpholinophenyl)guanidine fumarate), were examined in the stable cultured BRIN-BD11 cell line. BTS 67 582 (100–400 μM) stimulated a concentration-dependent increase (PBTS 67 582 in culture time-dependently decreased subsequent responsiveness to acute challenge with 200 μM BTS 67 582 or 200 μM tolbutamide at 12–18 h (PBTS 67 582 and tolbutamide. Culture with 100 μM BTS 67 582 or 100 μM tolbutamide did not affect basal insulin secretion, cellular insulin content, or cell viability and exerted no influence on the secretory responsiveness to 200 μM of the imidazoline, efaroxan. While 18 h BTS 67 582 culture did not affect the insulin-releasing actions (PBTS 67 582 shares a common signalling pathway to sulphonylurea but not imidazoline drugs. Desensitization of drug action may provide an important approach to dissect sites of action of novel and established insulinotropic antidiabetic agents. PMID:10807689

  11. Radioprotection of vitamin D on mice injured by irradiation

    International Nuclear Information System (INIS)

    Wang Xiaohui; Zhou Zhengyu; Li Bingyan; Nie Jihua; Tong Jian; Zhang Zengli

    2008-01-01

    To investigate the radioprotective effect of vitamin D against irradiation injury, the mice exposed to 60 Co γ-rays at 6 Gy was treated with preparation of vitamin D(Alfacalcidol Soft Capsules). Cell cycle and apoptosis was analyzed by flow cytometry (FCM) following staining of cells with propidium iodide (PI). Peripheral blood cell counts were analyzed by autoanalyzer. It has been found that vitamin D significantly increases white blood cell (WBC) counts, decreases bone marrow PEC micronucleus rate. FCM analysis shows that compared with damaged group, G2 and S phases of bone marrow cells in vitamin D protection group increases significantly at 24 h after whole body irradiation, whereas G1 phase cells decrease at the same times. So vitamin D might be a new radioprotection agent and it should be deserved further study. (authors)

  12. The 3rd irradiation test plan of DUPIC fuel

    Energy Technology Data Exchange (ETDEWEB)

    Yang, Myung Seung; Song, K. C.; Park, J. H. and others

    2001-05-01

    The objective of the 3rd irradiation test of DUPIC fuel at the HANARO is to estimate the in-core behaviour of a DUPIC pellet that is irradiated up to more than average burnup of CANDU fuel. The irradiation of DUPIC fuel is planned to start at May 21, 2001, and will be continued at least for 8 months. The burnup of DUPIC fuel through this irradiation test is thought to be more than 7,000 MWd/tHE. The DUPIC irradiation rig instrumented with three SPN detectors will be used to accumulate the experience for the instrumented irradiation and to estimate the burnup of irradiated DUPIC fuel more accurately. Under normal operating condition, the maximum linear power of DUPIC fuel was estimated as 55.06 kW/m, and the centerline temperature of a pellet was calculated as 2510 deg C. In order to assess the integrity of DUPIC fuel under the accident condition postulated at the HANARO, safety analyses on the locked rotor and reactivity insertion accidents were carried out. The maximum centerline temperature of DUPIC fuel was estimated 2590 deg C and 2094 deg C for each accident, respectively. From the results of the safety analysis, the integrity of DUPIC fuel during the HANARO irradiation test will be secured. The irradiated DUPIC fuel will be transported to the IMEF. The post-irradiation examinations are planned to be performed at the PIEF and IMEF.

  13. Irradiation testing of high-density uranium alloy dispersion fuels

    International Nuclear Information System (INIS)

    Hayes, S.L.; Trybus, C.L.; Meyer, M.K.

    1997-01-01

    Two irradiation test vehicles have been designed, fabricated, and inserted into the Advanced Test Reactor in Idaho. Irradiation of these experiments began in August 1997. These irradiation tests were designed to obtain irradiation performance information on a variety of potential new, high-density dispersion fuels. Each of the two irradiation vehicles contains 32 'microplates'. Each microplate is aluminum clad, having an aluminum matrix phase and containing one of the following compositions as the fuel phase: U-10Mo, U-8Mo, U-6Mo, U-4Mo, U-9Nb-3Zr, U-6Nb-4Zr, U-5Nb-3Zr, U-6Mo-1Pt, U-6Mo-0.6Ru, U10Mo-0.05Sn, U2Mo, or U 3 Si 2 . These experiments will be discharged at peak fuel burnups of approximately 40 and 80 at.% U 235 . Of particular interest are the extent of reaction of the fuel and matrix phases and the fission gas retention/swelling characteristics of these new fuel alloys. This paper presents the design of the irradiation vehicles and the irradiation conditions. (author)

  14. Irradiation tests of critical components for remote handling system in gamma radiation environment

    International Nuclear Information System (INIS)

    Obara, Kenjiro; Kakudate, Satoshi; Oka, Kiyoshi

    1996-03-01

    This report covers the gamma ray irradiation tests according to the Agreement of ITER R and D Task (T35) in 1994 and describes radiation hardness of the standard components for the ITER remote handling system which are categorized into the robotics (Subtask-1), the viewing system (Subtask-2) and the common components (Subtask-3). The gamma ray irradiation tests have been conducted using No.2 and No.3 cells at the cobalt building of Takasaki Establishment in JAERI. The radiation source is cobalt sixty (Co-60), and the maximum dose rate of No.2 and No.3 cells is about 1x10 6 R/h and 2x10 6 R/h, respectively. The environmental conditions of the irradiation tests are described below and all of components excepting electrical wires have been tested in the No.2 cell. [No.2 cell : Atmosphere and ambient temperature No.3 cell : Nitrogen gas and 250degC] As a whole, many of components have been irradiated up to the rated dose of around 1x10 10 rads and the following main results are obtained. The developed AC servo motor and periscope for radiation use have shown excellent durability with the radiation hardness tolerable for more than 10 9 rads. An electrical connector compatible with remote operation has also shown no degradation of electrical characteristics after the irradiation of 10 10 rads. As for polyimide insulated wires, the mechanical and electrical characteristics are not degradated after the irradiation of 10 9 rads and more radiation hardness can be expected than the anticipation. On the contrary, standard position sensors such as rotary encoder show extremely low radiation hardness and further efforts have to be made for improvements. (J.P.N.)

  15. New JMTR irradiation test plan on fuels and materials

    International Nuclear Information System (INIS)

    Nakamura, Takehiko; Nishiyama, Yutaka; Chimi, Yasuhiro; Sasajima, Hideo; Ogiyanagi, Jin; Nakamura, Jinichi; Suzuki, Masahide; Kawamura, Hiroshi

    2009-01-01

    In order to maintain and enhance safety of light water reactors (LWRs) in long-term and up-graded operations, proper understanding of irradiation behavior of fuels and materials is essentially important. Japanese government and the Japan Atomic Energy Agency (JAEA) have decided to refurbish the Japan Materials Testing Reactor (JMTR) and to install new tests rigs, in order to play an active role for solving irradiation related issues on plant aging and high-duty uses of the current LWRs and on development of next-generation reactors. New tests on fuel integrity under simulated abnormal transients and high-duty irradiation conditions are planned in the JMTR. Power ramp tests of newdesign fuel rods will also be performed in the first stage of the program, which is expected to start in year 2011 after refurbishment of the JMTR. Combination of the JMTR tests with simulated reactivity initiated accident tests in the Nuclear Safety Research Reactor (NSRR) and loss of coolant accident tests in hot laboratories would serve as the integrated fuel safety research on the high performance fuels at extended burnups, covering from the normal to the accident conditions, including abnormal transients. For the materials irradiation, fracture toughness of reactor vessel steels and stress corrosion cracking behavior of stainless steels are being studied in addition to basic irradiation behavior of nuclear materials such as hafnium. The irradiation studies would contribute not only to solve the current problems but also to identify possible seeds of troubles and to make proactive responses. (author)

  16. Utilization of half-embryo test to identify irradiated beans

    International Nuclear Information System (INIS)

    Villavicencio, Anna Lucia C.H.; Mancini-Filho, Jorge

    1996-01-01

    Germination tests were carried out in irradiated and non-irradiated bean seeds which allow to observe characteristically variations on the shoots and roots. The methodology used in this work, is based upon biological changes which occur in two Brazilian beans, Phaseolus vulgaris L., var. carioca and Vigna unguiculata (L.) Walp, var. macacar, irradiated in a 60 Co source, with doses of 0,0.5, 1.0, 2.5, 5.0 and 10.0 kGy. The shoots and roots were observed during 3 days of culturing period under specified conditions. The differences observed in these two varieties were analysed immediately after irradiation and after 6 months of storage period at room temperature. Irradiated half-embryos showed markedly reduced root grow and almost totally retarded shoot elongation. Differences between irradiated and nonirradiated half-embryo could be observed after irradiation when different beans and storage time were varied. The shoots of half-embryos irradiated with more than 2.5 kGy did not undergo any elongation, whereas, the shoots of non-irradiated or those beans irradiated under 1.0 kGy elongated significantly within the 3 day test period. (author)

  17. 40 CFR 58.2 - Purpose.

    Science.gov (United States)

    2010-07-01

    ... QUALITY SURVEILLANCE General Provisions § 58.2 Purpose. (a) This part contains requirements for measuring ambient air quality and for reporting ambient air quality data and related information. The monitoring... instruments or instrument probes. (5) Minimum ambient air quality monitoring network requirements used to...

  18. Evaluation of burnup characteristics and energy deposition during NSRR pulse irradiation tests on irradiated BWR fuels

    International Nuclear Information System (INIS)

    Nakamura, Takehiko; Yoshinaga, Makio

    2000-11-01

    Pulse irradiation tests of irradiated fuel are performed in the Nuclear Safety Research Reactor (NSRR) to investigate the fuel behavior under Reactivity Initiated Accident Conditions (RIA). The severity of the RIA is represented by energy deposition or peak fuel enthalpy during the power excursion. In case of the irradiated fuel tests, the energy deposition varies depending both on the amounts and distribution of residual fissile and neutron absorbing fission products generated during the base irradiation. Thus, proper fuel burnup characterization, especially for low enriched commercial fuels, is important, because plutonium (Pu) takes a large part of fissile and its generation depends on the neutron spectrum during the base irradiation. Fuel burnup calculations were conducted with ORIGEN2, RODBURN and SWAT codes for the BWR fuels tested in the NSRR. The calculation results were compared with the measured isotope concentrations and used for the NSRR neutron calculations to evaluate energy depositions of the test fuel. The comparison of the code calculations and the measurements revealed that the neutron spectrum change due to difference in void fraction altered Pu generation and energy deposition in the NSRR tests considerably. With the properly evaluated neutron spectrum, the combined burnup and NSRR neutron calculation gave reasonably good evaluation of the energy deposition. The calculations provided radial distributions of the fission product accumulation during the base irradiation and power distribution during the NSRR pulse irradiation, which were important for the evaluation of both burnup characteristics and fission gas release behavior. (author)

  19. Radiation hardness tests of double-sided 3D strip sensors with passing-through columns

    Energy Technology Data Exchange (ETDEWEB)

    Dalla Betta, Gian-Franco, E-mail: gianfranco.dallabetta@unitn.it [Dipartimento di Ingegneria Industriale, Università degli Studi di Trento, Via Sommarive 9, I-38123 Trento (Italy); INFN TIFPA, Via Sommarive 14, I-38123 Trento (Italy); Betancourt, Christopher [Institute of Physics, University of Freiburg, Hermann-Herder-Str. 3, 79104 Freiburg (Germany); Boscardin, Maurizio; Giacomini, Gabriele [Fondazione Bruno Kessler, Centro per i Materiali e i Microsistemi (FBK-CMM), Via Sommarive 18, I-38123 Trento (Italy); Jakobs, Karl; Kühn, Susanne [Institute of Physics, University of Freiburg, Hermann-Herder-Str. 3, 79104 Freiburg (Germany); Lecini, Besnik [Dipartimento di Ingegneria Industriale, Università degli Studi di Trento, Via Sommarive 9, I-38123 Trento (Italy); Mendicino, Roberto [Dipartimento di Ingegneria Industriale, Università degli Studi di Trento, Via Sommarive 9, I-38123 Trento (Italy); INFN TIFPA, Via Sommarive 14, I-38123 Trento (Italy); Mori, Riccardo; Parzefall, Ulrich [Institute of Physics, University of Freiburg, Hermann-Herder-Str. 3, 79104 Freiburg (Germany); Povoli, Marco [Dipartimento di Ingegneria Industriale, Università degli Studi di Trento, Via Sommarive 9, I-38123 Trento (Italy); Thomas, Maira [Institute of Physics, University of Freiburg, Hermann-Herder-Str. 3, 79104 Freiburg (Germany); Zorzi, Nicola [Fondazione Bruno Kessler, Centro per i Materiali e i Microsistemi (FBK-CMM), Via Sommarive 18, I-38123 Trento (Italy)

    2014-11-21

    This paper deals with a radiation hardness study performed on double-sided 3D strip sensors with passing-through columns. Selected results from the characterization of the irradiated sensors with a beta source and a laser setup are reported and compared to pre-irradiation results and to TCAD simulations. The sensor performance in terms of signal efficiency is found to be in good agreement with that of other 3D sensors irradiated at the same fluences and tested under similar experimental conditions. - Highlights: • We report results from 3D silicon strip detectors irradiated up to HL-LHC fluences. • I–V curves, noise, charge collection measurements and laser scans are shown. • In all sensors, signals are distinguished from the noise already at low voltage. • Signal efficiency is in agreement with values expected from the electrode geometry. • Efficiency and spatial uniformity would benefit from higher operation voltages.

  20. Radiation hardness tests of double-sided 3D strip sensors with passing-through columns

    International Nuclear Information System (INIS)

    Dalla Betta, Gian-Franco; Betancourt, Christopher; Boscardin, Maurizio; Giacomini, Gabriele; Jakobs, Karl; Kühn, Susanne; Lecini, Besnik; Mendicino, Roberto; Mori, Riccardo; Parzefall, Ulrich; Povoli, Marco; Thomas, Maira; Zorzi, Nicola

    2014-01-01

    This paper deals with a radiation hardness study performed on double-sided 3D strip sensors with passing-through columns. Selected results from the characterization of the irradiated sensors with a beta source and a laser setup are reported and compared to pre-irradiation results and to TCAD simulations. The sensor performance in terms of signal efficiency is found to be in good agreement with that of other 3D sensors irradiated at the same fluences and tested under similar experimental conditions. - Highlights: • We report results from 3D silicon strip detectors irradiated up to HL-LHC fluences. • I–V curves, noise, charge collection measurements and laser scans are shown. • In all sensors, signals are distinguished from the noise already at low voltage. • Signal efficiency is in agreement with values expected from the electrode geometry. • Efficiency and spatial uniformity would benefit from higher operation voltages

  1. Crack-arrest tests on two irradiated high-copper welds

    International Nuclear Information System (INIS)

    Iskander, S.K.; Corwin, W.R.; Nanstad, R.K.

    1994-03-01

    The objective of the Heavy-Section Steel Irradiation Program Sixth Irradiation Series is to determine the effect of neutron irradiation on the shift and shape of the lower-bound curve to crack-arrest toughness data. Two submerged-arc welds with copper contents of 0.23 and 0.31 wt % were commercially fabricated in 220-mm-thick plate. Crack-arrest specimens fabricated from these welds were irradiated at a nominal temperature of 288 degrees C to an average fluence of 1.9 x 10 19 neutrons/cm 2 (>1 MeV). This is the second report giving the results of the tests on irradiated duplex-type crack-arrest specimens. A previous report gave results of tests on irradiated weld-embrittled-type specimens. Charpy V-notch (CVN) specimens irradiated in the same capsules as the crack-arrest specimens were also tested, and a 41-J transition temperature shift was determined from these specimens. open-quotes Mean close-quote curves of the same form as the American Society of Mechanical Engineers (ASME) K la curve were fit to the data with only the open-quotes reference temperatureclose quotes as a parameter. The shift between the mean curves agrees well with the 41-J transition temperature shift obtained from the CVN specimen tests. Moreover, the four data points resulting from tests on the duplex crack-arrest specimens of the present study did not make a significant change to mean curve fits to either the previously obtained data or all the data combined

  2. An investigation of neutron irradiation test on superplastic zirconia-ceramic materials

    International Nuclear Information System (INIS)

    Shibata, Taiju; Ishihara, Masahiro; Baba, Shinichi; Hayashi, Kimio

    2000-05-01

    A neutron irradiation test on superplastic ceramic materials at high temperature has been proposed as an innovative basic research on high-temperature engineering using the High Temperature Engineering Test Reactor (HTTR). For the effective execution of the test, we reviewed the superplastic deformation mechanism of ceramic materials and discussed neutron irradiation effects on the superplastic deformation process of stabilized Tetragonal Zirconia Polycrystal (TZP), which is a representative superplastic ceramic material. As a result, we pointed out that the decrease in the activation energy for superplastic deformation is expected by the radiation-enhanced diffusion. We selected a fast neutron fluence of 5x10 20 n/cm 2 and an irradiation temperature of about 600degC as test conditions for the first irradiation test on TZP and decided to perform a preliminary irradiation test by the Japan Materials Testing Reactor (JMTR). Moreover, we estimated the radioactivity of irradiated TZP and indicated that it is in the order of 10 10 Bq/g (about 0.3 Ci/g) immediately after irradiation to a thermal neutron fluence of 3x10 20 n/cm 2 and that it decays to about 1/100 in a year. (author)

  3. Out-pile Test of Double Cladding Fuel Rod Mockups for a Nuclear Fuel Irradiation Test

    Energy Technology Data Exchange (ETDEWEB)

    Sohn, Jaemin; Park, Sungjae; Kang, Younghwan; Kim, Harkrho; Kim, Bonggoo; Kim, Youngki [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2008-05-15

    An instrumented capsule for a nuclear fuel irradiation test has been developed to measure fuel characteristics, such as a fuel temperature, internal pressure of a fuel rod, a fuel pellet elongation and a neutron flux during an irradiation test at HANARO. In the future, nuclear fuel irradiation tests under a high temperature condition are expected from users. To prepare for this request, we have continued developing the technology for a high temperature nuclear fuel irradiation test at HANARO. The purpose of this paper is to verify the possibility that the temperature of a nuclear fuel can be controlled at a high temperature during an irradiation test. Therefore we designed and fabricated double cladding fuel rod mockups. And we performed out-pile tests using these mockups. The purposes of a out-pile test is to analyze an effect of a gap size, which is between an outer cladding and an inner cladding, on the temperature and the effect of a mixture ratio of helium gas and neon gas on the temperature. This paper presents the design and fabrication of double cladding fuel rod mockups and the results of the out-pile test.

  4. Mobile IP and protocol authentication extension

    OpenAIRE

    Nguyen, Phuc V.

    2011-01-01

    Mobile IP is an open standard, defined by the Internet Engineering Task Force (IETF) RFC 3220. By using Mobile IP, you can keep the same IP address, stay connected, and maintain ongoing applications while roaming between IP networks. Mobile IP is scalable for the Internet because it is based on IP - any media that can support IP can support Mobile IP.

  5. Non-destructive test for irradiated fuels using X-ray CT system in hot-laboratory

    International Nuclear Information System (INIS)

    Kim, Heemoon; Kim, Gil-Soo; Yoo, Boung-Ok; Tahk, Young-Wook; Cho, Moon-Sung; Ahn, Sang-Bok

    2015-01-01

    To inspect inside of irradiated fuel rod for PIE in hotcell, neutron beam and X-ray have been used. Many hot laboratories in the world have shown the results for NDT by 2-D film data. Currently, computed image processing technology instead of film has been developed and CT was applied to the X-ray and neutron beam system. In this trend, our facility needed to set up X-ray system for irradiated fuel inspection and installed in hotcell with consideration of radiation damage. In this study, X-ray system was tested to be operated with radioactive samples and was performed to inspect fuel rods and observe internal damage and dimensional change. 450kV X-ray CT system was installed in hotcell with modification and tested to check image resolution and radiation damage. The image data were analyzed by 3-D computer software. 8 fuel plates and VHTR rods were inspected and measured internal shape and dimension

  6. Intense neutron irradiation facility for fusion reactor materials

    Energy Technology Data Exchange (ETDEWEB)

    Noda, Kenji; Oyama, Yukio; Kato, Yoshio; Sugimoto, Masayoshi [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    1997-03-01

    Technical R and D of d-Li stripping type neutron irradiation facilities for development of fusion reactor materials was carried out in Fusion Materials Irradiation Test Facility (FMIT) project and Energy Selective Neutron Irradiation Test Facility (ESNIT) program. Conceptual design activity (CDA) of International Fusion Materials Irradiation Facility (IFMIF), of which concept is an advanced version of FMIT and ESNIT concepts, are being performed. Progress of users` requirements and characteristics of irradiation fields in such neutron irradiation facilities, and outline of baseline conceptual design of IFMIF were described. (author)

  7. Multiformat decoder for a DSP-based IP set-top box

    Science.gov (United States)

    Pescador, F.; Garrido, M. J.; Sanz, C.; Juárez, E.; Samper, D.; Antoniello, R.

    2007-05-01

    Internet Protocol Set-Top Boxes (IP STBs) based on single-processor architectures have been recently introduced in the market. In this paper, the implementation of an MPEG-4 SP/ASP video decoder for a multi-format IP STB based on a TMS320DM641 DSP is presented. An initial decoder for PC platform was fully tested and ported to the DSP. Using this code an optimization process was started achieving a 90% speedup. This process allows real-time MPEG-4 SP/ASP decoding. The MPEG-4 decoder has been integrated in an IP STB and tested in a real environment using DVD movies and TV channels with excellent results.

  8. Electrical characterization of FBK small-pitch 3D sensors after γ-ray, neutron and proton irradiations

    Science.gov (United States)

    Dalla Betta, G.-F.; Boscardin, M.; Hoeferkamp, M.; Mendicino, R.; Seidel, S.; Sultan, D. M. S.

    2017-11-01

    In view of applications in the tracking detectors at the High Luminosity LHC (HL-LHC), we have developed a new generation of 3D pixel sensors featuring small-pitch (50 × 50 or 25 × 100 μ m2) and thin active layer (~ 100 μ m). Owing to the very short inter-electrode distance (~ 30 μ m), charge trapping effects can be strongly mitigated, making these sensors extremely radiation hard. However, the downscaled sensor structure also lends itself to high electric fields as the bias voltage is increased, motivating investigation of leakage current increase in order to prevent premature electrical breakdown due to impact ionization. In order to assess the characteristics of heavily irradiated samples, using 3D diodes as test devices, we have carried out a dedicated campaign that included several irradiations (γ -rays, neutrons, and protons) at different facilities. In this paper, we report on the electrical characterization of a subset of the irradiated samples, also in comparison to their pre-irradiation properties. Results demonstrate that hadron irradiated devices can be safely operated at a voltage high enough to allow for full depletion (hence high efficiency) also at the maximum fluence foreseen at the HL-LHC.

  9. Impact of genome assembly status on ChIP-Seq and ChIP-PET data mapping

    Directory of Open Access Journals (Sweden)

    Sachs Laurent

    2009-12-01

    Full Text Available Abstract Background ChIP-Seq and ChIP-PET can potentially be used with any genome for genome wide profiling of protein-DNA interaction sites. Unfortunately, it is probable that most genome assemblies will never reach the quality of the human genome assembly. Therefore, it remains to be determined whether ChIP-Seq and ChIP-PET are practicable with genome sequences other than a few (e.g. human and mouse. Findings Here, we used in silico simulations to assess the impact of completeness or fragmentation of genome assemblies on ChIP-Seq and ChIP-PET data mapping. Conclusions Most currently published genome assemblies are suitable for mapping the short sequence tags produced by ChIP-Seq or ChIP-PET.

  10. ejIP: A TCP/IP Stack for Embedded Java

    DEFF Research Database (Denmark)

    Schoeberl, Martin

    2011-01-01

    present the design and implementation of a network stack written entirely in Java. This implementation serves as an example how to implement system functions in a safe language and gives evidence that Java can be used for operating system related functionality. The described TCP/IP stack ejIP has already...

  11. Multi-physic simulations of irradiation experiments in a technological irradiation reactor; Modelisation pluridisciplinaire d'experiences d'irradiation dans un reacteur d'irradiation technologique

    Energy Technology Data Exchange (ETDEWEB)

    Bonaccorsi, Th

    2007-09-15

    A Material Testing Reactor (MTR) makes it possible to irradiate material samples under intense neutron and photonic fluxes. These experiments are carried out in experimental devices localised in the reactor core or in periphery (reflector). Available physics simulation tools only treat, most of the time, one physics field in a very precise way. Multi-physic simulations of irradiation experiments therefore require a sequential use of several calculation codes and data exchanges between these codes: this corresponds to problems coupling. In order to facilitate multi-physic simulations, this thesis sets up a data model based on data-processing objects, called Technological Entities. This data model is common to all of the physics fields. It permits defining the geometry of an irradiation device in a parametric way and to associate information about materials to it. Numerical simulations are encapsulated into interfaces providing the ability to call specific functionalities with the same command (to initialize data, to launch calculations, to post-treat, to get results,... ). Thus, once encapsulated, numerical simulations can be re-used for various studies. This data model is developed in a SALOME platform component. The first application case made it possible to perform neutronic simulations (OSIRIS reactor and RJH) coupled with fuel behavior simulations. In a next step, thermal hydraulics could also be taken into account. In addition to the improvement of the calculation accuracy due to the physical phenomena coupling, the time spent in the development phase of the simulation is largely reduced and the possibilities of uncertainty treatment are under consideration. (author)

  12. Performance Analysis of the Mobile IP Protocol (RFC 3344 and Related RFCS)

    Science.gov (United States)

    2006-12-01

    field of 9 identifies the ICMP message as an adverstisement . Code Mobile IP home agents and foreign agents use the value of 16 to prevent any nodes...ANALYSIS OF THE MOBILE IP PROTOCOL (RFC 3344 AND RELATED RFCS) by Chin Chin Ng December 2006 Thesis Co-Advisors: George W. Dinolt J. D...December 2006 3. REPORT TYPE AND DATES COVERED Master’s Thesis 4. TITLE AND SUBTITLE Performance Analysis of the Mobile IP Protocol (RFC 3344 and

  13. APLIKASI SERVER VIRTUAL IP UNTUK MIKROKONTROLER

    OpenAIRE

    Ashari, Ahmad

    2008-01-01

    Selama ini mikrokontroler yang terhubung ke satu komputer hanya dapat diakses melalui satu IP saja, padahal kebanyakan sistem operasi sekarang dapat memperjanjikan lebih dari satu IP untuk setiap komputer dalam bentuk virtual IP. Penelitian ini mengkaji pemanfaatan virtual IP dari IP aliasing pada sistem operasi Linux sebagai Server Virtual IP untuk mikrokontroler. Prinsip dasar Server Virtual IP adalah pembuatan Virtual Host pada masing-masing IP untuk memproses paket-paket data dan menerjem...

  14. Design considerations of the irradiation test vehicle for the advanced test reactor

    Energy Technology Data Exchange (ETDEWEB)

    Tsai, H.; Gomes, I.C.; Smith, D.L. [Argonne National Lab., IL (United States)] [and others

    1997-08-01

    An irradiation test vehicle (ITV) for the Advanced Test Reactor (ATR) is being jointly developed by the Lockheed Martin Idaho Technologies Company (LMIT) and the U.S. Fusion Program. The vehicle is intended for neutron irradiation testing of candidate structural materials, including vanadium-based alloys, silicon carbide composites, and low activation steels. It could possibly be used for U.S./Japanese collaboration in the Jupiter Program. The first test train is scheduled to be completed by September 1998. In this report, we present the functional requirements for the vehicle and a preliminary design that satisfies these requirements.

  15. Design considerations of the irradiation test vehicle for the advanced test reactor

    International Nuclear Information System (INIS)

    Tsai, H.; Gomes, I.C.; Smith, D.L.

    1997-01-01

    An irradiation test vehicle (ITV) for the Advanced Test Reactor (ATR) is being jointly developed by the Lockheed Martin Idaho Technologies Company (LMIT) and the U.S. Fusion Program. The vehicle is intended for neutron irradiation testing of candidate structural materials, including vanadium-based alloys, silicon carbide composites, and low activation steels. It could possibly be used for U.S./Japanese collaboration in the Jupiter Program. The first test train is scheduled to be completed by September 1998. In this report, we present the functional requirements for the vehicle and a preliminary design that satisfies these requirements

  16. GluD1 is a common altered player in neuronal differentiation from both MECP2-mutated and CDKL5-mutated iPS cells.

    Science.gov (United States)

    Livide, Gabriella; Patriarchi, Tommaso; Amenduni, Mariangela; Amabile, Sonia; Yasui, Dag; Calcagno, Eleonora; Lo Rizzo, Caterina; De Falco, Giulia; Ulivieri, Cristina; Ariani, Francesca; Mari, Francesca; Mencarelli, Maria Antonietta; Hell, Johannes Wilhelm; Renieri, Alessandra; Meloni, Ilaria

    2015-02-01

    Rett syndrome is a monogenic disease due to de novo mutations in either MECP2 or CDKL5 genes. In spite of their involvement in the same disease, a functional interaction between the two genes has not been proven. MeCP2 is a transcriptional regulator; CDKL5 encodes for a kinase protein that might be involved in the regulation of gene expression. Therefore, we hypothesized that mutations affecting the two genes may lead to similar phenotypes by dysregulating the expression of common genes. To test this hypothesis we used induced pluripotent stem (iPS) cells derived from fibroblasts of one Rett patient with a MECP2 mutation (p.Arg306Cys) and two patients with mutations in CDKL5 (p.Gln347Ter and p.Thr288Ile). Expression profiling was performed in CDKL5-mutated cells and genes of interest were confirmed by real-time RT-PCR in both CDKL5- and MECP2-mutated cells. The only major change in gene expression common to MECP2- and CDKL5-mutated cells was for GRID1, encoding for glutamate D1 receptor (GluD1), a member of the δ-family of ionotropic glutamate receptors. GluD1 does not form AMPA or NMDA glutamate receptors. It acts like an adhesion molecule by linking the postsynaptic and presynaptic compartments, preferentially inducing the inhibitory presynaptic differentiation of cortical neurons. Our results demonstrate that GRID1 expression is downregulated in both MECP2- and CDKL5-mutated iPS cells and upregulated in neuronal precursors and mature neurons. These data provide novel insights into disease pathophysiology and identify possible new targets for therapeutic treatment of Rett syndrome.

  17. IP3 stimulates CA++ efflux from fusogenic carrot protoplasts

    International Nuclear Information System (INIS)

    Rincon, M.; Boss, W.F.

    1986-01-01

    Polyphosphoinositide breakdown plays an important role in signal transduction in animal cells (Berridge and Irvine, 1984, Nature, 312:315). Upon stimulation, phospholipase C hydrolyzes phosphatidylinositol 4,5-bisphosphate to inositol 1,4,5-trisphosphate (IP 3 ) and diacylglycerol both of which act as cellular second messengers. IP 3 mobilizes Ca ++ from internal stores, hence the cytosolic free Ca ++ concentration increases and those physiological activities regulated by Ca ++ are stimulated. To test if plant cells also responded to IP 3 , Ca ++ efflux studies were done with fusogenic carrot protoplasts released in EGTA. The protoplasts were preloaded with 45 Ca ++ placed in a Ca ++ -free medium, and efflux determined as 45 Ca ++ loss from the protoplasts. IP 3 (10-20μM) caused enhanced 45 Ca ++ efflux and the response was sustained for at least 15 min. In plants, as in animals, the observed IP 3 -enhanced 45 Ca ++ efflux suggested that IP 3 released Ca ++ from internal stores, and the increased free cytosolic Ca ++ activated Ca ++ pumping mechanisms which restored the Ca ++ concentration in the cytosol to the normal level

  18. The relation of innate and adaptive immunity with viral-induced acute asthma attacks: Focusing on IP-10 and cathelicidin.

    Science.gov (United States)

    Arikoglu, T; Akyilmaz, E; Yildirim, D D; Batmaz, S B; Ulger, S T; Aslan, G; Kuyucu, S

    Despite growing evidence suggesting potential association between innate and adaptive immunity in viral-induced acute asthma, there is paucity of data in this area. This study aimed to investigate the association of innate and adaptive immunity with acute asthma attacks by analysing the role of IFN-γ-inducible protein 10 (IP-10), TLR2, cathelicidin, vitamin D and cytokines. This prospective study included 33 patients with viral-induced acute asthma and 30 children with controlled asthma. Nasopharyngeal swab samples were collected for virus identification and asthma attack scores assessed in acute asthma group. Blood sampling for IP-10, TLR2, cathelicidin, vitamin D levels, and spirometric indices were employed. Serum IP-10 and cathelicidin levels of acute asthma group were significantly higher and vitamin D levels were lower than controlled asthma group (IP-10; p=0.006, cathelicidin; p=0.002, vitamin D; pasthma attack severity (p=0.03) in acute asthma group. Higher cathelicidin values showed significant positive relation to IP-10 (beta coefficient: 33, p=0.02). Serum IP-10 levels higher than 38.9pg/ml (sensitivity: 85%, specificity: 47%, p=0.002) were predictive of virus-induced asthma. Serum IP-10 and vitamin D levels were found to be significantly related to viral-asthma attacks (IP-10; aOR: 8.93, p=0.03 and vitamin D; aOR: 0.82, p=0.001). Innate immunity biomarkers such as serum IP-10 and cathelicidin can be used to predict viral-induced acute asthma. These biomarkers may provide potential new treatment targets for acute asthma. Copyright © 2016 SEICAP. Published by Elsevier España, S.L.U. All rights reserved.

  19. Spectroscopy of the red star in IP Peg

    International Nuclear Information System (INIS)

    Martin, J.S.; Jones, D.H.P.; Friend, M.T.; Smith, R.C.

    1989-01-01

    CCD spectroscopy of the cataclysmic variable IP Pegasi during decline from outburst shows narrow chromospheric emission lines from the irradiated face of the red star. The He I (7065 A) emission line is used to produce a partial radial velocity curve, with K He =293.2±3.3 km s -1 . A reanalysis of previous Na I doublet (8190 A) absorption line data produces a considerably larger semi-amplitude, K abs , than previously published. However, this is larger than the true semi-amplitude, K 2 , because irradiation from the disc ionizes the NaI on the inner face of the red star and decreases the strength of the NaI doublet on that face. A computer simulation of the secondary radial velocity curve, including this ionization effect, is used to estimate the true semi-amplitude of the secondary motion. This gives K 2 =298±8 km s -1 . (author)

  20. Drug Interactions between some antiepileptic and certain hypocholesterolaemic drugs in irradiated animals

    International Nuclear Information System (INIS)

    Shaaban, D.M.L.

    2015-01-01

    Drug Interactions between antiepileptic drug such as phenytoin and certain hypercholesterolaemia drug namely rosuvastatin were investigated on several biological parameters. Phenytoin (60 mg/kg i.p) and rosuvastatin (1.25 mg/kg i.p) were given either alone and in combination to normal and irradiated animals to investigate drug interactions between the test drugs. Anticonvulsant activity was evaluated using pentylenetetrazole in a dose (80 mg/kg i.p) in normal and irradiated mice. Brain neurotransmitters (glutamate and GABA) were investigated. Lipid profile (total cholesterol (TC), Triacylglycerol (TG), High density lipoprotein-cholesterol (HDL-C) and low density lipoprotein- cholesterol (LDL-C) were determined. Liver functions such as serum Aspartate amino transferase (AST) and serum alanine amino transferase (ALT) were also estimated. Oxidative stress bio markers namely serum malondialdehyde (MDA), serum nitric oxide (NO) and blood superoxide dismutase activity (SOD) were studied. Histopathological examinations of brain and liver tissues were performed. Administration of phenytoin concurrently with rosuvastatin is not recommended in patients receiving radiotherapy as dangerous side effects on liver functions and lipid profile may occur. The interactions between the two drugs in normal rats improve liver functions and lipid peroxidation. Apart from the action of the combination on total cholesterol, it improves lipid profile pattern. Rosuvastatin administration in combination with phenytoin may have additive anticonvulsant activity.

  1. LVDT Development for High Temperature Irradiation Test and Application

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Chul Yong; Ban, Chae Min; Choo, Kee Nam; Jun, Byung Hyuk [KAERI, Daejeon (Korea, Republic of)

    2016-05-15

    The LVDT (Linear Variable Differential Transformer) is used to measure the elongation and pressure of a nuclear fuel rod, or the creep and fatigue of the material during a reactor irradiation test. This device must be a radiation-resistant LVDT for use in a research reactor. Norway Halden has LVDTs for an irradiation test by the own development and commercialized. But Halden's LVDTs have limited the temperature of the use until to 350 .deg. C. So, KAERI has been developing a new LVDT for high temperature irradiation test. This paper describes the design of a LVDT, the fabrication process of a LVDT, and the result of the performance test. The designed LVDT uses thermocouple cable for coil wire material and one MI cable as signal cable. This LVDT for a high temperature irradiation test can be used until a maximum of 900 .deg. C. Welding is a very important factor for the fabrication of an LVDT. We are using a 150W fiber laser welding system that consists of a welding head, monitoring vision system and rotary index.

  2. A germination test: an easy approach to know the irradiation

    International Nuclear Information System (INIS)

    Khawar, A.; Bhatti, I.A.; Bhatti, H.N.

    2010-01-01

    Food irradiation is an evolving preserving technique that provides a shield against the spoilage and might have a potential to ensure the food safety and security world wide. In the present study, feasibility to apply germination test to distinguish an un-irradiated and irradiated samples of wheat, maize, chickpea and black eye beans was checked. Samples were irradiated to the absorbed doses ranging from 0-10 kGy using Co-60 gamma irradiator and were germinated in plant growth chamber. Root and shoot lengths were measured at 7th day after gamma radiation treatment. In all the irradiated samples root and shoot lengths were decreased with the increase in radiation absorbed doses. The seeds irradiated to the absorbed doses more than 2 kGy were not germinated. Germination test proved as an easy and simple method to detect irradiation in wheat, maize, chickpea and black eye beans irradiated even at low absorbed doses. (author)

  3. Fabrication of High Temperature and High Pressure Vessel for the Fuel Test

    International Nuclear Information System (INIS)

    Park, Kook Nam; Lee, Jong Min; Sim, Bong Shick; Shon, Jae Min; Ahn, Seung Ho; Yoo, Seong Yeon

    2007-01-01

    The Fuel Test Loop(FTL) which is capable of an irradiation testing under a similar operating condition to those of PWR and CANDU nuclear power plants has been developed and installed in HANARO, KAERI. It is consisted of In-Pile Section(IPS) and Out-of Pile System(OPS). The IPS which is located inside the pool is divided into 3-parts; they are in-pool pipes, IVA(IPS Vessel Assembly) and the support structures. The test fuel is loaded inside a double wall, inner pressure vessel and outer pressure vessel, to keep the functionality of the reactor coolant pressure boundary. The localization of the IVA is achieved by manufacturing through local company and the functional test and verification were done through pressure drop, vibration, hydraulic and leakage tests. The brazing technique of the instrument lines has been checked for its functionality and yield. A IVA has been manufactured by local technique and will be finally tested under out of the high temperature and high pressure test

  4. The indication and the point at issue in total body irradiation (TBI)

    International Nuclear Information System (INIS)

    Kikuchi, Yuzo; Nishino, Shigeo.

    1992-01-01

    The role of radiation in the cause of interstitial pneumonitis (IP) was analysed here. Also optimal dose fractionation was discussed about total absorbed lung dose, dose rate and fractionation in spect of IP. After all optimal time schedule was recommended 3, 4 and 6 fraction of ≤ 4 Gy of fraction size using conventional and hyperfractionated irradiation. In the end the present condition and the point at issue in the irradiation of blood for prevention GVHD were discussed. (author)

  5. Preliminary Beam Irradiation Test for RI Production Targets at KOMAC

    Energy Technology Data Exchange (ETDEWEB)

    Yoon, Sang Pil; Kwon, Hyeok Jung; Kim, Han Sung; Cho, Yong Sub; Seol, Kyung Tae; Song, Young Gi; Kim, Dae Il; Jung, Myung Hwan; Kim, Kye Ryung; Min, Yi Sub [KAERI, Daejeon (Korea, Republic of)

    2016-05-15

    The new beamline and target irradiation facility has been constructed for the production of therapeutic radio-isotope. Sr-82 and Cu-67 were selected as the target isotope in this facility, they are promising isotope for the PET imaging and cancer therapy. For the facility commissioning, the irradiation test for the prototype-target was conducted to confirm the feasibility of radio-isotope production, the proto-type targets are made of RbCl pellet and the natural Zn metal for Sr-82 and Cu-67 production respectively, In this paper, an introduction to the RI production targetry system and the results of the preliminary beam irradiation test are discussed. the low-flux beam irradiation tests for proto-type RI target have been conducted. As a result of the beam irradiation tests, we could obtain the evidence of Sr-82 and Cu-67 production, have confirmed the feasibility of Sr-82 and Cu-67 production at KOMAC RI production facility.

  6. Preliminary Beam Irradiation Test for RI Production Targets at KOMAC

    International Nuclear Information System (INIS)

    Yoon, Sang Pil; Kwon, Hyeok Jung; Kim, Han Sung; Cho, Yong Sub; Seol, Kyung Tae; Song, Young Gi; Kim, Dae Il; Jung, Myung Hwan; Kim, Kye Ryung; Min, Yi Sub

    2016-01-01

    The new beamline and target irradiation facility has been constructed for the production of therapeutic radio-isotope. Sr-82 and Cu-67 were selected as the target isotope in this facility, they are promising isotope for the PET imaging and cancer therapy. For the facility commissioning, the irradiation test for the prototype-target was conducted to confirm the feasibility of radio-isotope production, the proto-type targets are made of RbCl pellet and the natural Zn metal for Sr-82 and Cu-67 production respectively, In this paper, an introduction to the RI production targetry system and the results of the preliminary beam irradiation test are discussed. the low-flux beam irradiation tests for proto-type RI target have been conducted. As a result of the beam irradiation tests, we could obtain the evidence of Sr-82 and Cu-67 production, have confirmed the feasibility of Sr-82 and Cu-67 production at KOMAC RI production facility

  7. PARAGON-IPS: A Portable Imaging Software System For Multiple Generations Of Image Processing Hardware

    Science.gov (United States)

    Montelione, John

    1989-07-01

    Paragon-IPS is a comprehensive software system which is available on virtually all generations of image processing hardware. It is designed for an image processing department or a scientist and engineer who is doing image processing full-time. It is being used by leading R&D labs in government agencies and Fortune 500 companies. Applications include reconnaissance, non-destructive testing, remote sensing, medical imaging, etc.

  8. Thrombogenicity tests on ar-irradiated polycarbonate foils

    Energy Technology Data Exchange (ETDEWEB)

    Trindade, Gustavo F.; Rizzutto, Marcia A.; Silva, Tiago F.; Moro, Marcos V.; Added, Nemitala; Tabacniks, Manfredo H., E-mail: g.ferraz@usp.br [Universidade de Sao Paulo (USP), Sao Paulo, SP (Brazil). Inst. de Fisica; Delgado, Adriana O. [Universidade Federal de Sao Carlos (UFSCAR), Sorocaba, SP (Brazil); Cunha, Tatiana F. [Biosintesis P and D do Brasil, Sao Paulo, SP (Brazil); Higa, Olga Z. [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil). Centro de Biotecnologia

    2013-07-01

    Understanding polymer surface properties is extremely important for the most wide range of their applications, from basic coating to the most complex composites and biomaterials. Low energy ion beam irradiation of polymer can improve such surface properties. By modifying its surface biocompatibility, polymers are excellent candidates for biomaterials, due to its malleability and low weight, when compared to metals. In this work, we irradiated 30-μm Bisphenol-A Polycarbonate foils with 23-keV Argon ion beam at six different doses. Aluminium foils were simultaneously irradiated in order to measure the doses by Rutherford Backscattering Spectroscopy. The surface modifications after the argon ion beam irradiation were analyzed by water contact angle measurements and atomic force microscopy. Platelet adhesion tests were used in order to investigate thrombogenicity, showing a growing tendency with the irradiated Argon dose. (author)

  9. Thrombogenicity tests on ar-irradiated polycarbonate foils

    International Nuclear Information System (INIS)

    Trindade, Gustavo F.; Rizzutto, Marcia A.; Silva, Tiago F.; Moro, Marcos V.; Added, Nemitala; Tabacniks, Manfredo H.; Cunha, Tatiana F.; Higa, Olga Z.

    2013-01-01

    Understanding polymer surface properties is extremely important for the most wide range of their applications, from basic coating to the most complex composites and biomaterials. Low energy ion beam irradiation of polymer can improve such surface properties. By modifying its surface biocompatibility, polymers are excellent candidates for biomaterials, due to its malleability and low weight, when compared to metals. In this work, we irradiated 30-μm Bisphenol-A Polycarbonate foils with 23-keV Argon ion beam at six different doses. Aluminium foils were simultaneously irradiated in order to measure the doses by Rutherford Backscattering Spectroscopy. The surface modifications after the argon ion beam irradiation were analyzed by water contact angle measurements and atomic force microscopy. Platelet adhesion tests were used in order to investigate thrombogenicity, showing a growing tendency with the irradiated Argon dose. (author)

  10. Comparing genome-wide chromatin profiles using ChIP-chip or ChIP-seq

    NARCIS (Netherlands)

    Johannes, Frank; Wardenaar, Rene; Colomé Tatché, Maria; Mousson, Florence; de Graaf, Petra; Mokry, Michal; Guryev, Victor; Timmers, H. Th. Marc; Cuppen, Edwin; Jansen, Ritsert C.; Bateman, Alex

    2010-01-01

    Motivation: ChIP-chip and ChIP-seq technologies provide genomewide measurements of various types of chromatin marks at an unprecedented resolution. With ChIP samples collected from different tissue types and/ or individuals, we can now begin to characterize stochastic or systematic changes in

  11. Development of endplug welding technology for irradiation testing capsule

    Energy Technology Data Exchange (ETDEWEB)

    Lee, J. W.; Shin, Y. T.; Kim, S. S.; Kim, B. K.; Kang, Y. H. [KAERI, Taejon (Korea, Republic of)

    2001-10-01

    To evaluate the performance of newly developed nuclear fuel, it is necessary to irradiate the fuel at a research reactor and examine the irradiated fuel. For the irradiation test in a reasearch reactor, a fuel assembly which is generally called a capsule should be fabricated, considering the fuel irradiation plan and the characteristics of the reactor to be used. And also the fuel elements containing the developed fuel pellets should be made and assembled into a capsule. In this study, the welding method, welding equipment, welding conditions and parameters were developed to make fuel elements for the irradiation test at the HANARO research reactor. The TIG welding method using automatic orbital tube welding system was adopted and the welding joint design was developed for the fabrication of various kinds of irradiation fuel elements. And the optimal welding conditions and parameters were also established for the endplug welding of Zircaloy-4 cladding tube.

  12. Time-differential observation of the ortho-para conversion of liquid D2 under irradiation

    International Nuclear Information System (INIS)

    Mishima, K.; Utsuro, M.; Nagai, Y.; Tanaka, M.; Kohmoto, T.; Fukuda, Y.; Kiyanagi, Y.; Ooi, M.

    2007-01-01

    We measured an absolute ortho-D 2 concentration of gas samples taken from irradiated liquid D 2 samples as a function of the integrated radiation dose and the irradiation time by means of a frequency-resolved Raman spectroscopy to study the ortho-D 2 conversion mechanism under irradiation. The measurement was carried out by irradiating liquid ortho-D 2 at a temperature of 25 K with Bremsstrahlung photons, which were produced by bombarding tantalum with 33 MeV electrons, and whose absolute fluxes were determined experimentally by employing a foil activation method. The obtained ortho-D 2 concentration was found to decrease from 98% to 82% monotonically with increasing the radiation dose, irrespective of the electron-beam power. This fact clearly indicates the important role of a radiation-induced breakup effect of the ortho D 2 under the present experimental conditions of radiation dose and irradiation time. The obtained conversion rate is ten times faster than the evaluated value based on an existing model, requiring an alternate mechanism to enhance the conversion

  13. Irradiation test plan of the simulated DUPIC fuel

    Energy Technology Data Exchange (ETDEWEB)

    Bae, Ki Kwang; Yang, M. S.; Kim, B. K. [Korea Atomic Energy Research Institute, Taejon (Korea)

    1999-11-01

    Simulated DUPIC fuel had been irradiated from Aug. 4, 1999 to Oct. 4 1999, in order to produce the data of its in-core behavior, to verify the design of DUPIC non-instrumented capsule developed, and to ensure the irradiation requirements of DUPIC fuel at HANARO. The welding process was certified for manufacturing the mini-element, and simulated DUPIC fuel rods were manufactured with simulated DUPIC pellets through examination and test. The non-instrumented capsule for a irradiation test of DUPIC fuel has been designed and manufactured referring to the design specification of the HANARO fuel. This is to be the design basis of the instrumented capsule under consideration. The verification experiment, whether the capsule loaded in the OR4 hole meet the HANARO requirements under the normal operation condition, as well as the structural analysis was carried out. The items for this experiment were the pressure drop test, vibration test, integrity test, et. al. It was noted that each experimental result meet the HANARO operational requirements. For the safety analysis of the DUPIC non-instrumented capsule loaded in the HANARO core, the nuclear/mechanical compatibility, thermodynamic compatibility, integrity analysis of the irradiation samples according to the reactor condition as well as the safety analysis of the HANARO were performed. Besides, the core reactivity effects were discussed during the irradiation test of the DUPIC capsule. The average power of each fuel rod in the DUPIC capsule was calculated, and maximal linear power reflecting the axial peaking power factor from the MCNP results was evaluated. From these calculation results, the HANARO core safety was evaluated. At the end of this report, similar overseas cases were introduced. 9 refs., 16 figs., 10 tabs. (Author)

  14. Strength and microstructure in vadium irradiated with T(d,n) neutrons at 300 to 675K

    International Nuclear Information System (INIS)

    Bradley, E.R.

    1984-12-01

    Tensile tests and microstructural examination have been conducted on vanadium wires and foils following T(d,n) neutron irradiation at 300K, 475K, and 675K. Similar increases in yield strength were measured for samples irradiated at 300K and 475K but less strengthening occurred during irradiation at 675K. Examination of the fracture surfaces showed that all samples failed by ductile rupture after attaining more than 95% reduction in area. A reasonable correlation between microstructures and strengthing was obtained using a simple dispersed barrier strengthening model. A high density of small defect clusters was responsible for strengthening after irradiation at 300K. Following irradiation at 475K, interstitial loops with a Burgers vectors were the predominant strengthening defect with a smaller contribution from a/2 type loops. A heterogeneous distribution of dislocation loops and planar precipitates prevented definite correlations between strength and microstructure in samples irradiated at 675K

  15. Comparing genome-wide chromatin profiles using ChIP-chip or ChIP-seq

    NARCIS (Netherlands)

    Johannes, F.; Wardenaar, R.; Colome-Tatche, M.; Mousson, F.; de Graaf, P.; Mokry, M.; Guryev, V.; Timmers, H.T.; Cuppen, E.; Jansen, R.

    2010-01-01

    MOTIVATION: ChIP-chip and ChIP-seq technologies provide genome-wide measurements of various types of chromatin marks at an unprecedented resolution. With ChIP samples collected from different tissue types and/or individuals, we can now begin to characterize stochastic or systematic changes in

  16. Neutron irradiation test of copper alloy/stainless steel joint materials

    International Nuclear Information System (INIS)

    Yamada, Hirokazu; Kawamura, Hiroshi

    2006-01-01

    As a study about the joint technology of copper alloy and stainless steel for utilization as cooling piping in International Thermonuclear Experimental Reactor (ITER), Al 2 O 3 -dispersed strengthened copper or CuCrZr was jointed to stainless steel by three kinds of joint methods (casting joint, brazing joint and friction welding method) for the evaluation of the neutron irradiation effect on joints. A neutron irradiation test was performed to three types of joints and each copper alloy. The average value of fast neutron fluence in this irradiation test was about 2 x 10 24 n/m 2 (E>1 MeV), and the irradiation temperature was about 130degC. As post-irradiation examinations, tensile tests, hardness tests and observation of fracture surface after the tensile tests were performed. All type joints changed to be brittle by the neutron irradiation effect like each copper alloy material, and no particular neutron irradiation effect due to the effect of joint process was observed. On the casting and friction welding, hardness of copper alloy near the joint boundary changed to be lower than that of each copper alloy by the effect of joint procedure. However, tensile strength of joints was almost the same as that of each copper alloy before/after neutron irradiation. On the other hand, tensile strength of joints by brazing changed to be much lower than CuAl-25 base material by the effect of joint process before/after neutron irradiation. Results in this study showed that the friction welding method and the casting would be able to apply to the joint method of piping in ITER. This report is based on the final report of the ITER Engineering Design Activities (EDA). (author)

  17. Design, fabrication and installation of irradiation facilities

    Energy Technology Data Exchange (ETDEWEB)

    Sim, Bong Shick; Kim, Y. S.; Lee, C. Y. and others

    1999-03-01

    The principal contents of this project are to design, fabricate and install the steady-state fuel test loop in HANARO for nuclear technology development. Procurement and fabrication of main equipment, licensing and technical review for fuel test loop have been performed during 2 years(1997, 1998) for this project. Following contents are described in the report. - Procurement and fabrication of the equipment, piping for OPS - IPS manufacture - License - Technical review and evaluation of the FTL facility. As besides, as these irradiation facilities will be installed in HANARO, review of safety concern, discussion with KINS for licensing and review ofHANARO interface have been performed respectively. (author)

  18. Fusion materials irradiation test facility: description and status

    International Nuclear Information System (INIS)

    Trego, A.L.; Parker, E.F.; Hagan, J.W.

    1982-01-01

    The Fusion Materials Irradiation Test (FMIT) Facility will generate a high-flux, high-energy neutron source that will provide a fusion-like radiation environment for fusion reactor materials development. The neutrons will be produced in a nuclear stripping reaction by impinging a 35 MeV beam of deuterons from an Alvarez-type linear accelerator on a flowing lithium target. The target will be located in a test cell which will provide an irradiation volume of over 750l within which 10 cm 3 will have an average neutron flux of greater than 1.4 x 10 15 n/cm 2 -s and 500 cm 3 an average flux of greater than 2.2 by 10 14 n/cm 2- s with an expected availability factor greater than 65%. The projected fluence within the 10 cm 3 high flux region of FMIT will effect damage upon the materials test specimens to 30 dpa (displacements per atom) for each 90 day irradiation period. This irradiation flux volume will be at least 500 times larger than that of any other facility with comparable neutron energy and will fully meet the fusion materials damage research objective of 100 dpa within three years for the first round of tests

  19. IP-10 release assays in the diagnosis of tuberculosis infection

    DEFF Research Database (Denmark)

    Ruhwald, Morten; Aabye, Martine G; Ravn, Pernille

    2012-01-01

    The current state-of-the-art tests for infection with Mycobacterium tuberculosis - the IFN-γ release assays - rely on accurate measurement of the cytokine IFN-γ. Many other potential biomarkers are expressed in concert with IFN-γ, and IP-10 in particular has shown promising results. IP-10...

  20. SpaceWire: IP, Components, Development Support and Test Equipment

    Science.gov (United States)

    Parkes, S.; McClements, C.; Mills, S.; Martin, I.

    SpaceWire is a communications network for use onboard spacecraft. It is designed to connect high data-rate sensors, large solid-state memories, processing units and the downlink telemetry subsystem providing an integrated data-handling network. SpaceWire links are serial, high-speed (2 Mbits/sec to 400 Mbits/sec), bi-directional, full-duplex, pointto- point data links which connect together SpaceWire equipment. Application information is sent along a SpaceWire link in discrete packets. Control and time information can also be sent along SpaceWire links. SpaceWire is defined in the ECSS-E50-12A standard [1]. With the adoption of SpaceWire on many space missions the ready availability of intellectual property (IP) cores, components, software drivers, development support, and test equipment becomes a major issue for those developing satellites and their electronic subsystems. This paper describes the work being done at the University of Dundee and STAR-Dundee Ltd with ESA, BNSC and internal funding to make these essential items available. STAR-Dundee is a spin-out company of the University of Dundee set up specifically to support users of SpaceWire.

  1. SP-100 Fuel Pin Performance: Results from Irradiation Testing

    Science.gov (United States)

    Makenas, Bruce J.; Paxton, Dean M.; Vaidyanathan, Swaminathan; Marietta, Martin; Hoth, Carl W.

    1994-07-01

    A total of 86 experimental fuel pins with various fuel, liner, and cladding candidate materials have been irradiated in the Experimental Breeder Reactor-II (EBR-II) and the Fast Flux Test Facility (FFTF) reactor as part of the SP-100 fuel pin irradiation testing program. Postirradiation examination results from these fuel pins are key in establishing performance correlations and demonstrating the lifetime and safety of the reactor fuel system. This paper provides a brief description of the in-reactor fuel pin tests and presents the most recent irradiation data on the performance of wrought rhenium (Re) liner material and high density UN fuel at goal burnup of 6 atom percent (at. %). It also provides an overview of the significant variety of other fuel/liner/cladding combinations which were irradiated as part of this program and which may be of interest to more advanced efforts.

  2. Fuel temperature prediction during high burnup HTGR fuel irradiation test. US-JAERI irradiation test for HTGR fuel

    International Nuclear Information System (INIS)

    Sawa, Kazuhiro; Fukuda, Kousaku; Acharya, R.

    1995-01-01

    This report describes the preirradiation thermal analysis of the HRB-22 capsule designed for an irradiation test in a removable beryllium position of the High Flux Isotope Reactor(HFIR) at Oak Ridge National Laboratory. This test is being carried out under Annex 2 of the Arrangement between the U.S. Department of Energy and the Japan Atomic Energy Research Institute on Cooperation in Research and Development regarding High-Temperature Gas-cooled Reactors. The fuel used in the test is an advanced type. The advanced fuel was designed aiming at burnup of about 10%FIMA(% fissions per initial metallic atom) which was higher than that of the first charge fuel for the High Temperature Engineering Test Reactor(HTTR) and was produced in Japan. CACA-2, a heavy isotope and fission product concentration calculational code for experimental irradiation capsules, was used to determine time-dependent fission power for the fuel compacts. The Heat Engineering and Transfer in Nine Geometries(HEATING) code was used to solve the steady-state heat conduction problem. The diameters of the graphite fuel body, which contains the fuel compacts, and of the primary pressure vessel were determined such that the requirements of running the fuel compacts at an average temperature less than 1250degC and of not exceeding a maximum fuel temperature of 1350degC were met throughout the four cycles of irradiation. The detail design of the capsule was carried out based on this analysis. (author)

  3. Which IP Strategies Do Young Highly Innovative Firms Choose

    DEFF Research Database (Denmark)

    Veugelers, Reinhilde; Schneider, Cédric

    2018-01-01

    This paper describes and analyzes the strategies of young highly innovative companies to appropriate the returns from their innovations. Upon controlling for other firm and industry characteristics, we show that firms combining a young age and small scale with a high R&D intensive profile are mor...... likely to use intellectual property (IP), specifically combining formal and informal appropriation mechanisms. They are especially more likely to choose secrecy in combination with formal IP. This holds primarily when they introduce more radical innovations new to the market....

  4. Irradiation effects test series, test IE-5. Test results report

    International Nuclear Information System (INIS)

    Croucher, D.W.; Yackle, T.R.; Allison, C.M.; Ploger, S.A.

    1978-01-01

    Test IE-5, conducted in the Power Burst Facility at the Idaho National Engineering Laboratory, employed three 0.97-m long pressurized water reactor type fuel rods, fabricated from previously irradiated zircaloy-4 cladding and one similar rod fabricated from unirradiated cladding. The objectives of the test were to evaluate the influence of simulated fission products, cladding irradiation damage, and fuel rod internal pressure on pellet-cladding interaction during a power ramp and on fuel rod behavior during film boiling operation. The four rods were subjected to a preconditioning period, a power ramp to an average fuel rod peak power of 65 kW/m, and steady state operation for one hour at a coolant mass flux of 4880 kg/s-m 2 for each rod. After a flow reduction to 1800 kg/s-m 2 , film boiling occurred on one rod. Additional flow reductions to 970 kg/s-m 2 produced film boiling on the three remaining fuel rods. Maximum time in film boiling was 80s. The rod having the highest initial internal pressure (8.3 MPa) failed 10s after the onset of film boiling. A second rod failed about 90s after reactor shutdown. The report contains a description of the experiment, the test conduct, test results, and results from the preliminary postirradiation examination. Calculations using a transient fuel rod behavior code are compared with the test results

  5. Shoot regeneration of callus culture from irradiated sheed of piper nigrum L by gamma rays

    International Nuclear Information System (INIS)

    Ishak; Hutabarat, D.

    1988-01-01

    Shoot regeneration was obtained from callus that induced by irradiated seed with 25 and 50 Gy of gamma-rays and then on M.S. medium containing NAA 1 ppm and 2-ip 0.5 ppm. Irradiated seed with a dose of 25 Gy produced normal root and failed to produce shoot, but rice callus. Irradiated seed with a dose of 50 Gy pruduce callus only. Shoot differentiation occured after the callus were cultured on M.S., medium containing 2-ip 1 ppm and Kinetin 2.5 ppm. (authors). 9 refs, 3 figs

  6. Proteomics of post-irradiation recovery in D. radiodurans

    International Nuclear Information System (INIS)

    Basu, Bhakti; Apte, Shree Kumar

    2012-01-01

    An extremophile Deinococcus radiodurans is bestowed with an extraordinary DNA repair ability that renders it virtually resistant to all known forms of DNA damage caused by ionizing radiations (10 kGy of gamma rays), UV (1 kJ/m 2 ) or weeks of desiccation etc. The genome of D. radiodurans encodes a unique combination of DNA repair pathways such as prokaryotic type RecFOR mediated homologous recombination (HR) and nucleotide/base excision repair along with eukaryotic type strand annealing (SA) and non-homologous end joining (NHEJ), but is devoid of universal prokaryotic DNA repair pathways such as RecBCD mediated HR, photo-reactivation and SOS response. Collective evidence obtained so far from multiple approaches, have indicated (i) that all genes essential for DNA repair are not necessarily induced following radiation stress (ii) early RecA independent DNA assembly occurs, and (iii) absolute necessity of RecA dependent HR for final genome restitution. The 6 kGy gamma irradiation inducible proteome dynamics were mapped during the post-irradiation growth arrest phase by 2D protein electrophoresis coupled with mass spectrometry. Radiation inducible expression of at least 33 proteins was evident in the first 1h of post irradiation recovery

  7. Calculation analysis of Wims/D4-Batan-2DIFF neutron spectrum on RSG-GAS with cadmium ratio

    International Nuclear Information System (INIS)

    Radianti, I.B.; Zuhair; Hamzah, A.

    1998-01-01

    The calculation analysis of WIMS/D4-BATAN-2DIFF neutron spectrum was performed by comparison the calculation result of cadmium ratio with the experiment result on CIP, IP2, IP3 and IP4 irradiation positions of RSG GAS tenth core. The foils of Au, Mn and Co were used for determination of the measured and calculated cadmium ratios. Spectrum calculation was done in 69 energy group with 541 energy group (till 10 MeV) cross section of foil absorption reaction. The difference values between cadmium ratio calculation and experiment result for all cases were in interval of 11.0%-26.3% which are out of measurement deviation range. From these result, it concluded that the use of WIM /D4 in generating group constant is not sufficient to obtain the neutron spectrum, especially for non-fuel region

  8. Ensuring Software IP Cleanliness

    OpenAIRE

    Mahshad Koohgoli; Richard Mayer

    2007-01-01

    At many points in the life of a software enterprise, determination of intellectual property (IP) cleanliness becomes critical. The value of an enterprise that develops and sells software may depend on how clean the software is from the IP perspective. This article examines various methods of ensuring software IP cleanliness and discusses some of the benefits and shortcomings of current solutions.

  9. Application of half-embryo test to identify irradiated fresh fruits

    International Nuclear Information System (INIS)

    Abdelbary, N.A.; EL agamawy, M.R.

    2004-01-01

    Some countries already permit the irradiation of foods to extend its storage life and to control pests, therefore, a faster and significantly more uniform identification method are needed. Half-embryo test is based on the inhibition of shooting due to gamma irradiation since biological systems are sensitive to low doses of gamma irradiation. The intact fruits, apples, lemons, oranges and watermelons were obtained from the local market and irradiated directly with doses of 0.5, 0.75, 1.5 and 3 KGy. Shooting was defined as the elongation of the shoot to the extent of at least 1 mm length in apples and watermelon, while 0.5 mm length in citrus fruits. Root and shoot growth was stimulated most strongly by the addition of benzyladenine (2.5 mg/l) as a growth hormone. Shooting started after 1-3 days and reached to 90 % after 4 days. A long lasting half-embryo test (4-5 days) was capable to discriminate between irradiated and non-irradiated fruits. Growth of half-embryo and the changes were almost the same in all non-irradiated fruits under study. Growth of half-embryo irradiated with a dose of 0.5 KGy or more almost has totally retarded elongation of both root and shoot. Practically, it was observed that small-developed shoots showed slight elongation and afterward they were decayed. If shooting percentage after 1-3 days is less than 20% in apples, 40% in oranges and 30% in lemons and watermelons, the fruits are classified as i rradiated u nder 0.5 KGy as a detection limit dose of the irradiation. Irradiation caused obvious changes in root and shoot growth of half-embryos studied. Roots of non-irradiated half-embryos grew well in all fruits under study and those irradiated with 0.5 KGy or more were obviously reduced. In the same way, shoots of non-irradiated half-embryo grew well and shooting percentage reached to 50 % after 1-2 days and those fruits irradiated with 0.5 KGy or more were reduced. It is recommended to employ the half-embryo test as a practical technique

  10. Gevaar VoIP voor telecomsector overdreven

    NARCIS (Netherlands)

    Deventer, M.O. van; Wegberg, M. van

    2004-01-01

    Het is een hype Voice-over-IP (VoIP) voor te stellen als een ontwrichtende technologie die de telecomindustrie ingrijpend zal veranderen. Maar hoe ontwrichtend is VoIP eigenlijk? Oskar van Deventer en Marc van Wegberg analyseren drie vormen van VoIP en laten zien dat alleen ‘VoIP-chat’ potentieel

  11. Space Network IP Services (SNIS): An Architecture for Supporting Low Earth Orbiting IP Satellite Missions

    Science.gov (United States)

    Israel, David J.

    2005-01-01

    The NASA Space Network (SN) supports a variety of missions using the Tracking and Data Relay Satellite System (TDRSS), which includes ground stations in White Sands, New Mexico and Guam. A Space Network IP Services (SNIS) architecture is being developed to support future users with requirements for end-to-end Internet Protocol (IP) communications. This architecture will support all IP protocols, including Mobile IP, over TDRSS Single Access, Multiple Access, and Demand Access Radio Frequency (RF) links. This paper will describe this architecture and how it can enable Low Earth Orbiting IP satellite missions.

  12. IFMIF [International Fusion Materials Irradiation Facility], an accelerator-based neutron source for fusion components irradiation testing: Materials testing capabilities

    International Nuclear Information System (INIS)

    Mann, F.M.

    1988-08-01

    The International Fusion Materials Irradiation Facility (IFMIF) is proposed as an advanced accelerator-based neutron source for high-flux irradiation testing of large-sized fusion reactor components. The facility would require only small extensions to existing accelerator and target technology originally developed for the Fusion Materials Irradiation Test (FMIT) facility. At the extended facility, neutrons would be produced by a 0.1-A beam of 35-MeV deuterons incident upon a liquid lithium target. The volume available for high-flux (>10/sup 15/ n/cm/sup 2/-s) testing in IFMITF would be over a liter, a factor of about three larger than in the FMIT facility. This is because the effective beam current of 35-MeV deuterons on target can be increased by a factor of ten to 1A or more. Such an increase can be accomplished by funneling beams of deuterium ions from the radio-frequency quadruple into a linear accelerator and by taking advantage of recent developments in accelerator technology. Multiple beams and large total current allow great variety in available testing. For example, multiple simultaneous experiments, and great flexibility in tailoring spatial distributions of flux and spectra can be achieved. 5 refs., 2 figs., 1 tab

  13. Cell death induced by gamma irradiation of developing skeletal muscle

    International Nuclear Information System (INIS)

    Olive, M.; Blanco, R.; Rivera, R.; Cinos, C.; Ferrer, I.

    1995-01-01

    Newborn Sprague-Dawley rats were exposed to a single dose of 2 Gy gamma rays and killed from 6 h to 5 d later. Increased numbers of dying cells, characterised by their extreme chromatin condensation and often nuclear fragmentation were seen in skeletal muscle 6 h after irradiation. Dying cells decreased to nearly normal values 48 h later. In situ labelling of nuclear DNA fragmentation identified individual cells bearing fragmented DNA. The effects of gamma rays were suppressed following cycloheximide i.p. at a dose of 1 μg/g body weight given at the time of irradiation. Taken together, the present morphological and pharmacological results suggest that gamma ray induced cell death in skeletal muscle is apoptotic, and that the process is associated with protein synthesis. Finally, proliferating cell nuclear antigen-immunoreactive cells, which were abundant in control rats, decreased in number 48 h after irradiation. However, a marked increase significantly above normal age values was observed at the 5th day, thus suggesting that regeneration occurs following irradiation-induced cell death in developing muscle. (author)

  14. Irradiation cryostat for LiH and LiD polarized solid targets

    International Nuclear Information System (INIS)

    Goertz, S.

    1991-01-01

    Scattering experiments with polarized nucleon targets are an important tool to understand the nuclear spin structure. Pion photoproduction experiments on polarized protrons and neutrons as well as measurements of the neutron and deuteron formfactors will be performed at ELSA. 7 LiH and 6 LiD seem to be attractive target materials for these experiments, because they offer high proton and deuteron polarisation, respectively. Expecially 6 LiD has further very important advantages compared to the common deuteron target materials as d-Butanol and ND 3 . This work describes the mechanism of DNP (Dynamic Nuclear Polarization) in LiH and LiD and gives a view on the nature of the so-called paramagnetic impurities in these materials. In order to maximize the nuclear polarization, the production of these radicals have to take place under well defined temperature conditions. Therefore the first version of an irradiation cryostat was built and tested in regard to its cooling power and temperature adjustment. (orig.)

  15. Detection methods for irradiated mites and insects

    International Nuclear Information System (INIS)

    Ignatowicz, S.

    1999-01-01

    Results of the study on the following tests for separation of irradiated pests from untreated ones are reported: (a) test for identification of irradiated mites (Acaridae) based on lack of fecundity of treated females; (b) test for identification of irradiated beetles based on their locomotor activity; (c) test for identification of irradiated pests based on electron spin resonance (ESR) signal derived from treated insects; (d) test for identification of irradiated pests based on changes in the midgut induced by gamma radiation; and (e) test for identification of irradiated pests based on the alterations in total proteins of treated adults. Of these detection methods, only the test based on the pathological changes induced by irradiation in the insect midgut may identify consistently either irradiated larvae or adults. This test is simple and convenient when a rapid processing technique for dehydrating and embedding the midgut is used. (author)

  16. JOYO-1 Irradiation Test Campaign Technical Close-out, For Information

    International Nuclear Information System (INIS)

    G. Borges

    2006-01-01

    The JOYO-1 irradiation testing was designed to screen the irradiation performance of candidate cladding, structural and reflector materials in support of space reactor development. The JOYO-1 designation refers to the first of four planned irradiation tests in the JOYO reactor. Limited irradiated material performance data for the candidate materials exists for the expected Prometheus-1 duration, fluences and temperatures. Materials of interest include fuel element cladding and core materials (refractory metal alloys and silicon carbide (Sic)), vessel and plant structural materials (refractory metal alloys and nickel-base superalloys), and control and reflector materials (BeO). Key issues to be evaluated were long term microstructure and material property stability. The JOYO-1 test campaign was initiated to irradiate a matrix of specimens at prototypical temperatures and fluences anticipated for the Prometheus-1 reactor [Reference (1)]. Enclosures 1 through 9 describe the specimen and temperature monitors/dosimetry fabrication efforts, capsule design, disposition of structural material irradiation rigs, and plans for post-irradiation examination. These enclosures provide a detailed overview of Naval Reactors Prime Contractor Team (NRPCT) progress in specific areas; however, efforts were in various states of completion at the termination of NRPCT involvement with and restructuring of Project Prometheus

  17. JOYO-1 Irradiation Test Campaign Technical Close-out, For Information

    Energy Technology Data Exchange (ETDEWEB)

    G. Borges

    2006-01-31

    The JOYO-1 irradiation testing was designed to screen the irradiation performance of candidate cladding, structural and reflector materials in support of space reactor development. The JOYO-1 designation refers to the first of four planned irradiation tests in the JOYO reactor. Limited irradiated material performance data for the candidate materials exists for the expected Prometheus-1 duration, fluences and temperatures. Materials of interest include fuel element cladding and core materials (refractory metal alloys and silicon carbide (Sic)), vessel and plant structural materials (refractory metal alloys and nickel-base superalloys), and control and reflector materials (BeO). Key issues to be evaluated were long term microstructure and material property stability. The JOYO-1 test campaign was initiated to irradiate a matrix of specimens at prototypical temperatures and fluences anticipated for the Prometheus-1 reactor [Reference (1)]. Enclosures 1 through 9 describe the specimen and temperature monitors/dosimetry fabrication efforts, capsule design, disposition of structural material irradiation rigs, and plans for post-irradiation examination. These enclosures provide a detailed overview of Naval Reactors Prime Contractor Team (NRPCT) progress in specific areas; however, efforts were in various states of completion at the termination of NRPCT involvement with and restructuring of Project Prometheus.

  18. Ensuring Software IP Cleanliness

    Directory of Open Access Journals (Sweden)

    Mahshad Koohgoli

    2007-12-01

    Full Text Available At many points in the life of a software enterprise, determination of intellectual property (IP cleanliness becomes critical. The value of an enterprise that develops and sells software may depend on how clean the software is from the IP perspective. This article examines various methods of ensuring software IP cleanliness and discusses some of the benefits and shortcomings of current solutions.

  19. Inert medium (helium) irradiation testing of pressure tube samples

    International Nuclear Information System (INIS)

    Ancuta, M.; Radu, V.; Stefan, V.; Preda, M.

    2001-01-01

    Irradiation tests currently performed in C-5 capsule aim at obtaining data and information concerning behavior to irradiation of pressure tubes of CANDU type fuel channel, to evidence the factors limiting operation life span. A calculation code for analysis and prediction of pressure tube behavior should be based upon periodical inspection results, post irradiation examination of the removed from reactor pressure tubes as well as on the experimental results obtained with materials subjected to irradiation conditions identical with the operational ones. Mechanical behavior analysis should focus both complex thermal-mechanical type stresses and mechanical properties alteration under irradiation. The experimental results should be applied: - to evaluate the irradiation effects upon mechanical properties of Zr-2.5% Nb exposed to fluences up to 10 21 n·cm -2 ; - to gather data concerning the real stress / real deformation characteristic from which characteristic quantities can be deduced as, for instance, elasticity modulus, plasticity modulus, exponent of stress term in the Tsu-Berteles relation, to be used within the CANTUP simulation code describing pressure tube behavior, currently developed at INR Pitesti; - to develop prediction methods of pressure tube behavior and merging with in-service inspection procedure in order to forecast the life span and the proper timing for replacement before major failures occur. The samples irradiated in C-5 capsule were extracted from the ends of Zr-2.5% Nb pressure tubes resulting from Cernavoda NPP Unit 1. The samples for tensile tests were extracted on longitudinal and transversal directions of the pressure tube. The tests were carried out under following conditions: - test environment temperature, 260 - 280 deg.C; - testing medium, helium at 1 - 6 b pressure; - neutron flux (E n > 1 MeV), 1 - 2 · 10 13 ncm -2 s -1 ; - neutron fluence (E n > 1 MeV), 4 · 10 20 ncm -2 . The following characteristics were obtained from tensile

  20. Web-based IP telephony penetration system evaluating level of protection from attacks and threats

    OpenAIRE

    Vozňák, Miroslav; Řezáč, Filip

    2011-01-01

    This article deals with detection of threats in IP telephony, the authors developed a penetration testing system that is able to check up the level of protection from security threats in IP telephony. SIP is being widely used in building VoIP networks. Unlike the traditional telephone networks VoIP networks does not have a closed communication which makes communication medium vulnerable to all kinds of attacks from the in truders. The SIP server is a key component of VoIP infrastr...

  1. 21 CFR 582.5994 - Zinc stearate.

    Science.gov (United States)

    2010-04-01

    ..., FEEDS, AND RELATED PRODUCTS SUBSTANCES GENERALLY RECOGNIZED AS SAFE Nutrients and/or Dietary Supplements 1 § 582.5994 Zinc stearate. (a) Product. Zinc stearate prepared from stearic acid free from chick-edema factor. (b) Conditions of use. This substance is generally recognized as safe when used in...

  2. Implementasi Protokol Keamanan TLS pada Aplikasi Layanan Komunikasi Suara Melalui Jaringan TCP/IP (VoIP)

    OpenAIRE

    Hariady, Ricky

    2011-01-01

    Saat ini layanan komunikasi suara melalui jaringan TCP/IP atau yang lebih dikenal dengan VoIP (Voice over IP) telah semakin banyak digunakan, namun teknologi VoIP yang ada saat ini masih rentan terhadap penyadapan ataupun pencurian data. Sementara protokol kriptografi TLS (Transport Layer Security) telah teruji dan banyak digunakan untuk mengamankan komunikasi melalui internet seperti pada layanan email dan web. Dengan mengimplementasikan protokol TLS pada sebuah aplikasi Vo...

  3. Comparison of DNA comet assay and germination test (half-embryo-test) in gamma-irradiated cherry seeds

    International Nuclear Information System (INIS)

    Todoroki, Setsuko; Hayashi, Toru

    2002-01-01

    Cherry fruits were irradiated with gamma-rays at doses up to 200Gy (effective dose for disinfestation of codling moth), and DNA strand break in seed embryos was investigated by using alkaline comet assay. Immediately after irradiation (≥100Gy), DNA from embryos produced comets with a long and wide tail due to fragmentation. In control cells, DNA relaxed and produced comet with very short tail (with few strand break). After 72h storage, DNA from fruits irradiated at 200 Gy showed comets with little tail and tail moment of comets was same as un-irradiated control. These results indicate that the strand breaks of DNA caused by irradiation in fresh seed embryo are repaired during storage. On the contrary, the ability of germination lost by irradiation did not restored, a dose of 100Gy and more retarded shoot elongation. In cherries irradiated at 100Gy, the shooting percentage was less than 50% at 4th day after incubation. Germination test (Half embryo test) can be discriminate between irradiated and un-irradiated cherries. (author)

  4. Postirradiation examination results for the Irradiation Effects Scoping Test 2

    International Nuclear Information System (INIS)

    Mehner, A.S.

    1977-01-01

    The postirradiation examination results are reported for two rods from the second scoping test (IE-ST-2) of the Nuclear Regulatory Commission Irradiation Effects Program. The rods were irradiated in the in-pile test loop of the Power Burst Facility at the Idaho National Engineering Laboratory. Rod IE-005 was fabricated from fresh fuel and cladding previously irradiated in the Saxton Reactor. Rod IE-006, fabricated from fresh fuel and unirradiated cladding, was equipped with six developmental cladding surface thermocouples. The rods were preconditioned, power ramped, and then subjected to film boiling operation. The performance of the rods and the developmental thermocouples are evaluated from the post irradiation examination results. The effects of prior irradiation damage in cladding are discussed in relation to fuel rod behavior during a power ramp and subsequent film boiling operation

  5. Irradiation and testing of compact ignition tokamak toroidal field coil insulation materials

    International Nuclear Information System (INIS)

    Kanemoto, G.K.; Sherick, M.J.; Sparks, D.C.

    1990-05-01

    This report documents the results of an irradiation and testing program performed on behalf of Martin Marietta Energy Systems, Inc. in support of the Compact Ignition Tokamak Research and Development program. The purpose of the irradiation and testing program was to determine the effects of neutron and gamma irradiation on the mechanical and electrical properties of candidate toroidal field coil insulation materials. Insulation samples were irradiated in the Advanced Test Reactor (ATR) in a large I-hole. The insulation samples were irradiated within a lead shield to reduce exposure to gamma radiation to better approximate the desired ration of neutron to gamma exposure. Two different exposure levels were specified for the insulation samples. To accomplish this, the samples were encapsulated in two separate aluminum capsules; the capsules positioned at the ATR core mid-plane and at the top of the fueled region to take advantage of the axial cosine distribution of the neutron and gamma flux; and by varying the length of irradiation time of the two capsules. Disassembly of the irradiated capsules and testing of the insulation samples were performed at the Test Reactor Area (TRA) Hot Cell Facilities. Testing of the samples included shear compression static, shear compression fatigue, flexure static, and electrical resistance measurements

  6. PIE on Safety-Tested Loose Particles from Irradiated Compact 4-4-2

    Energy Technology Data Exchange (ETDEWEB)

    Hunn, John D. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Gerczak, Tyler J. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Morris, Robert Noel [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Baldwin, Charles A. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States); Montgomery, Fred C. [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2016-04-01

    Post-irradiation examination (PIE) is being performed in support of tristructural isotropic (TRISO) coated particle fuel development and qualification for High Temperature Gas-cooled Reactors (HTGRs). This work is sponsored by the Department of Energy Office of Nuclear Energy (DOE-NE) through the Advanced Reactor Technologies (ART) Office under the Advanced Gas Reactor Fuel Development and Qualification (AGR) Program. The AGR-1 experiment was the first in a series of TRISO fuel irradiation tests initiated in 2006. The AGR-1 TRISO particles and fuel compacts were fabricated at Oak Ridge National Laboratory (ORNL) in 2006 using laboratory-scale equipment and irradiated for 3 years in the Advanced Test Reactor (ATR) at Idaho National Laboratory (INL) to demonstrate and evaluate fuel performance under HTGR irradiation conditions. Post-irradiation examination was performed at INL and ORNL to study how the fuel behaved during irradiation, and to test fuel performance during exposure to elevated temperatures at or above temperatures that could occur during a depressurized conduction cooldown event. This report summarizes safety testing and post-safety testing PIE conducted at ORNL on loose particles extracted from irradiated AGR-1 Compact 4-4-2.

  7. AGR-1 Irradiation Test Final As-Run Report, Rev. 3

    Energy Technology Data Exchange (ETDEWEB)

    Collin, Blaise P. [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2015-01-01

    This document presents the as-run analysis of the AGR-1 irradiation experiment. AGR-1 is the first of eight planned irradiations for the Advanced Gas Reactor (AGR) Fuel Development and Qualification Program. Funding for this program is provided by the US Department of Energy (DOE) as part of the Next-Generation Nuclear Plant (NGNP) project. The objectives of the AGR-1 experiment are: 1. To gain experience with multi-capsule test train design, fabrication, and operation with the intent to reduce the probability of capsule or test train failure in subsequent irradiation tests. 2. To irradiate fuel produced in conjunction with the AGR fuel process development effort. 3. To provide data that will support the development of an understanding of the relationship between fuel fabrication processes, fuel product properties, and irradiation performance. In order to achieve the test objectives, the AGR-1 experiment was irradiated in the B-10 position of the Advanced Test Reactor (ATR) at the Idaho National Laboratory (INL) for a total duration of 620 effective full power days of irradiation. Irradiation began on December 24, 2006 and ended on November 6, 2009 spanning 13 ATR cycles and approximately three calendar years. The test contained six independently controlled and monitored capsules. Each capsule contained 12 compacts of a single type, or variant, of the AGR coated fuel. No fuel particles failed during the AGR-1 irradiation. Final burnup values on a per compact basis ranged from 11.5 to 19.6 %FIMA, while fast fluence values ranged from 2.21 to 4.39 x 1025 n/m2 (E >0.18 MeV). We’ll say something here about temperatures once thermal recalc is done. Thermocouples performed well, failing at a lower rate than expected. At the end of the irradiation, nine of the originally-planned 19 TCs were considered functional. Fission product release-to-birth (R/B) ratios were quite low. In most capsules, R/B values at the end of the irradiation were at or below

  8. Recent irradiation tests for future nuclear system at HANARO

    Energy Technology Data Exchange (ETDEWEB)

    Cho, Man Soon; Choo, Kee Nam; Yang, Seong Woo; Park, Sang Jun [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2016-05-15

    The capsule at HANARO is a device that evaluates the irradiation effects of nuclear materials and fuels, which can reproduce the environment of nuclear power plants and accelerate to reach to the end of life condition. As the integrity assessment and the extension of lifetime of nuclear power plants are recently considered as important issues in Korea, the requirements for irradiation test are gradually being increased. The capacity and capability irradiation tests at HANARO are becoming important because Korea strives to develop SFR (Sodium-cooled Fast Reactor) and VHTR (Very High Temperature Reactor) among the future nuclear system and to export the research reactors and to develop the fusion reactor technology.

  9. 21 CFR 582.5065 - Linoleic acid.

    Science.gov (United States)

    2010-04-01

    ..., FEEDS, AND RELATED PRODUCTS SUBSTANCES GENERALLY RECOGNIZED AS SAFE Nutrients and/or Dietary Supplements 1 § 582.5065 Linoleic acid. (a) Product. Linoleic acid prepared from edible fats and oils and free from chick-edema factor. (b) Conditions of use. This substance is generally recognized as safe when...

  10. Foundations of hardware IP protection

    CERN Document Server

    Torres, Lionel

    2017-01-01

    This book provides a comprehensive and up-to-date guide to the design of security-hardened, hardware intellectual property (IP). Readers will learn how IP can be threatened, as well as protected, by using means such as hardware obfuscation/camouflaging, watermarking, fingerprinting (PUF), functional locking, remote activation, hidden transmission of data, hardware Trojan detection, protection against hardware Trojan, use of secure element, ultra-lightweight cryptography, and digital rights management. This book serves as a single-source reference to design space exploration of hardware security and IP protection. · Provides readers with a comprehensive overview of hardware intellectual property (IP) security, describing threat models and presenting means of protection, from integrated circuit layout to digital rights management of IP; · Enables readers to transpose techniques fundamental to digital rights management (DRM) to the realm of hardware IP security; · Introduce designers to the concept of salutar...

  11. Ühisjooned sillutavad koostööd / Stephen Ip ; interv. Kristo Kiviorg

    Index Scriptorium Estoniae

    Ip, Stephen

    2007-01-01

    Ilmunud ka: Delovõje Vedomosti 20. juuni lk. 13. Hongkongi erihaldusregiooni majandus- ja tööhõiveminister Stephen Ip vastab küsimustele Eesti ja Hongkongi vahelise logistikakoostöö võimaluste kohta. Kommenteerib Elar Kilumets

  12. Multi-physic simulations of irradiation experiments in a technological irradiation reactor; Modelisation pluridisciplinaire d'experiences d'irradiation dans un reacteur d'irradiation technologique

    Energy Technology Data Exchange (ETDEWEB)

    Bonaccorsi, Th

    2007-09-15

    A Material Testing Reactor (MTR) makes it possible to irradiate material samples under intense neutron and photonic fluxes. These experiments are carried out in experimental devices localised in the reactor core or in periphery (reflector). Available physics simulation tools only treat, most of the time, one physics field in a very precise way. Multi-physic simulations of irradiation experiments therefore require a sequential use of several calculation codes and data exchanges between these codes: this corresponds to problems coupling. In order to facilitate multi-physic simulations, this thesis sets up a data model based on data-processing objects, called Technological Entities. This data model is common to all of the physics fields. It permits defining the geometry of an irradiation device in a parametric way and to associate information about materials to it. Numerical simulations are encapsulated into interfaces providing the ability to call specific functionalities with the same command (to initialize data, to launch calculations, to post-treat, to get results,... ). Thus, once encapsulated, numerical simulations can be re-used for various studies. This data model is developed in a SALOME platform component. The first application case made it possible to perform neutronic simulations (OSIRIS reactor and RJH) coupled with fuel behavior simulations. In a next step, thermal hydraulics could also be taken into account. In addition to the improvement of the calculation accuracy due to the physical phenomena coupling, the time spent in the development phase of the simulation is largely reduced and the possibilities of uncertainty treatment are under consideration. (author)

  13. Irradiation tests of radiation resistance optical fibers for fusion diagnostic application

    Science.gov (United States)

    Kakuta, Tsunemi; Shikama, Tatsuo; Nishitani, Takeo; Yamamoto, Shin; Nagata, Shinji; Tsuchiya, Bun; Toh, Kentaro; Hori, Junichi

    2002-11-01

    To promote development of radiation-resistant core optical fibers, the ITER-EDA (International Thermonuclear Experimental Reactor-Engineering Design Activity) recommended carrying out international round-robin irradiation tests of optical fibers to establish a reliable database for their applications in the ITER plasma diagnostics. Ten developed optical fibers were irradiation-tested in a Co-60 gamma cell, a Japan Materials Testing Reactor (JMTR). Also, some of them were irradiation tested in a fast neutron irradiation facility of FNS (Fast Neutron Source), especially to study temperature dependence of neutron-associated irradiation effects. Included were several Japanese fluorine doped fibers and one Japanese standard fiber (purified and undoped silica core), as well as seven Russian fibers. Some of Russian fibers were drawn by Japanese manufactures from Russian made pre-form rods to study effects of manufacturing processes to radiation resistant properties. The present paper will describe behaviors of growth of radiation-induced optical transmission loss in the wavelength range of 350-1750nm. Results indicate that role of displacement damages by fast neutrons are very important in introducing permanent optical transmission loss. Spectra of optical transmission loss in visible range will depend on irradiation temperatures and material parameters of optical fibers.

  14. AGR-5/6/7 Irradiation Test Predictions using PARFUME

    Energy Technology Data Exchange (ETDEWEB)

    Skerjanc, William F. [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2017-09-14

    PARFUME, (PARticle FUel ModEl) a fuel performance modeling code used for high temperature gas-cooled reactors (HTGRs), was used to model the Advanced Gas Reactor (AGR)-5/6/7 irradiation test using predicted physics and thermal hydraulics data. The AGR-5/6/7 test consists of the combined fifth, sixth, and seventh planned irradiations of the AGR Fuel Development and Qualification Program. The AGR-5/6/7 test train is a multi-capsule, instrumented experiment that is designed for irradiation in the 133.4-mm diameter north east flux trap (NEFT) position of Advanced Test Reactor (ATR). Each capsule contains compacts filled with uranium oxycarbide (UCO) unaltered fuel particles. This report documents the calculations performed to predict the failure probability of tristructural isotropic (TRISO)-coated fuel particles during the AGR-5/6/7 experiment. In addition, this report documents the calculated source term from the driver fuel. The calculations include modeling of the AGR-5/6/7 irradiation that is scheduled to occur from October 2017 to April 2021 over a total of 13 ATR cycles, including nine normal cycles and four Power Axial Locator Mechanism (PALM) cycle for a total between 500 – 550 effective full power days (EFPD). The irradiation conditions and material properties of the AGR-5/6/7 test predicted zero fuel particle failures in Capsules 1, 2, and 4. Fuel particle failures were predicted in Capsule 3 due to internal particle pressure. These failures were predicted in the highest temperature compacts. Capsule 5 fuel particle failures were due to inner pyrolytic carbon (IPyC) cracking causing localized stresses concentrations in the SiC layer. This capsule predicted the highest particle failures due to the lower irradiation temperature. In addition, shrinkage of the buffer and IPyC layer during irradiation resulted in formation of a buffer-IPyC gap. The two capsules at the two ends of the test train, Capsules 1 and 5 experienced the smallest buffer-IPyC gap

  15. Irradiated cocoa tested in the wing spot assay in Drosophila melanogaster

    International Nuclear Information System (INIS)

    Zimmering, S.; Olvera, O.; Cruces, M.P.; Pimentel, E.; Arceo, C.; Rosa, M.E. de la; Guzman, J.

    1992-01-01

    The result of treatment of Drosophila melanogaster with irradiated cocoa as scored in the somatic wing spot test is described. The test has been used previously in the evaluation of irradiated food and has registrated a significantly greater number of positives among chemicals tested than germ line counterparts. Irradiated cocoa has thus far been reported negative in other mutagenicity assays including those employing salmonella and Drosophila germ cells and mammalian cells. The wing spot test as described in Graf et al. was employed. Females of the genotype mwh were mated with flr 3 /TM3; Ser males. (author). 9 refs.; 1 tab

  16. Irradiation Effects Test Series: Test IE-2. Test results report

    International Nuclear Information System (INIS)

    Allison, C.M.; Croucher, D.W.; Ploger, S.A.; Mehner, A.S.

    1977-08-01

    The report describes the results of a test using four 0.97-m long PWR-type fuel rods with differences in diametral gap and cladding irradiation. The objective of this test was to provide information about the effects of these differences on fuel rod behavior during quasi-equilibrium and film boiling operation. The fuel rods were subjected to a series of preconditioning power cycles of less than 30 kW/m. Rod powers were then increased to 68 kW/m at a coolant mass flux of 4900 kg/s-m 2 . After one hour at 68 kW/m, a power-cooling-mismatch sequence was initiated by a flow reduction at constant power. At a flow of 2550 kg/s-m 2 , the onset of film boiling occurred on one rod, Rod IE-011. An additional flow reduction to 2245 kg/s-m 2 caused the onset of film boiling on the remaining three rods. Data are presented on the behavior of fuel rods during quasiequilibrium and during film boiling operation. The effects of initial gap size, cladding irradiation, rod power cycling, a rapid power increase, and sustained film boiling are discussed. These discussions are based on measured test data, preliminary postirradiation examination results, and comparisons of results with FRAP-T3 computer model calculations

  17. Differential expression of growth factors in irradiated mouse testes

    International Nuclear Information System (INIS)

    Mauduit, Claire; Siah, Ahmed; Foch, Marie; Chapet, Olivier; Clippe, Sebastien; Gerard, Jean-Pierre; Benahmed, Mohamed

    2001-01-01

    Purpose: By using as an experimental model the male mouse gonad, which contains both radiosensitive (germ) and radioresistant (somatic) cells, we have studied the growth factor (and/or receptor) expression of transforming growth factor-β receptor (TGFβ RI), stem cell factor (SCF), c-kit, Fas-L, Fas, tumor necrosis factor receptor (TNF R55), and leukemia inhibiting factor receptor (LIF-R) after local irradiation. Methods and Materials: Adult male mice were locally irradiated on the testes. Induction of apoptosis in the different testicular cell types following X-ray radiation was identified by the TdT-mediated dUTP Nick End Labeling (TUNEL) approach. Growth factor expression was evidenced by semiquantitative RT-PCR and Western blot analyses. Results: Apoptosis, identified through the TUNEL approach, occurred in radiosensitive testicular (premeotic) germ cells with the following kinetics: the number of apoptotic cells increased after 24 h (p<0.001) and was maximal 48 h after a 2-Gy ionizing radiation (p<0.001). Apoptotic cells were no longer observed 72 h after a 2-Gy irradiation. The number of apoptotic cells increased with the dose of irradiation (1-4 Gy). In the seminiferous tubules, the growth factor expression in premeiotic radiosensitive germ cells was modulated by irradiation. Indeed Fas, c-kit, and LIF-R expression, which occurs in (radiosensitive) germ cells, decreased 24 h after a 2-Gy irradiation, and the maximal decrease was observed with a 4-Gy irradiation. The decrease in Stra8 expression occurred earlier, at 4 h after a 2-Gy irradiation. In addition, a significant (p<0.03) decrease in Stra8 mRNA levels was observed at the lowest dose used (0.5 Gy, 48 h). Moreover, concerning a growth factor receptor, such as TGFβ RI, which is expressed both in radiosensitive and radioresistant cells, we observed a differential expression depending on the cell radiosensitivity after irradiation. Indeed, TGFβ RI expression was increased after irradiation in

  18. Effect of irradiation on the interaction between hydroxyzine and hexobarbital

    International Nuclear Information System (INIS)

    Nowakowska, E.; Wojciak, Z.; Godlewski, J.; Kozaryn, I.

    1984-01-01

    The effect of hydroxyzine (20 mg/kg, i.p.) on hypnotic activity and pharmacokinetics of hexobarbital (100 mg/kg, i.p.) in rats irradiated with X-rays (6 Gy) was studied. Hydroxyzine caused statistically significant prolongation of hexobarbital-induced sleep. It is in agreement with pharmacokinetical changes - prolonged biological half-life time and increased hexobarbital level in the brain tissue. (author)

  19. Irradiation test plan of instrumented capsule(05F-01K) for nuclear fuel irradiation in Hanaro (Revision 1)

    Energy Technology Data Exchange (ETDEWEB)

    Sohn, Jae Min; Kim, B. G.; Choi, M. H. (and others)

    2006-09-15

    An instrumented capsule was developed to be able to measure fuel characteristics, such as fuel temperature, internal pressure of fuel rod, fuel pellet elongation, and neutron flux, etc., during the irradiation test of nuclear fuel in HANARO. The instrumented capsule for measuring and monitoring fuel centerline temperature and neutron flux was designed and manufactured. And then, to verify the design of the instrumented capsule in the test hole, it was successfully irradiated in the test hole of HANARO from March 14, 2003 to June 1, 2003 (53.84 full power days at 24 MW). In the year of 2004, 3 test fuel rods and the 03F-05K instrumented fuel capsule were designed and fabricated to measure fuel centerline temperature, internal pressure of fuel rod, and fuel axial deformation during irradiation test. Now, this capsule was successfully irradiated in the test hole OR5 of HANARO reactor from April 27, 2004 to October 1, 2004 (59.5 full power days at 24-30 MW). The capsule and fuel rods have been be dismantled and fuel rods have been examined at the hot cell of IMEF. The instrumented fuel capsule (05F-01K) was designed and manufactured for a design verification test of the dual instrumented fuel rods. The irradiation test of the 05F-01K instrumented fuel capsule will be carried out at the OR5 vertical experimental hole of HANARO.

  20. 24 CFR 582.230 - Environmental review.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 3 2010-04-01 2010-04-01 false Environmental review. 582.230... Environmental review. (a) Activities under this part are subject to HUD environmental regulations in part 58 of this title, except that HUD will perform an environmental review in accordance with part 50 of this...

  1. In-pile IASCC growth tests of irradiated stainless steels in JMTR

    Energy Technology Data Exchange (ETDEWEB)

    Chimi, Yasuhiro; Kasahara, Shigeki; Ise, Hideo; Kawaguchi, Yoshihiko; Nakano, Junichi; Nishiyama, Yutaka [Japan Atomic Energy Agency, Nuclear Safety Research Center, Tokai, Ibaraki (Japan); Shibata, Akira; Ohmi, Masao [Japan Atomic Energy Agency, Oarai Research and Development Center, Oarai, Ibaraki (Japan)

    2012-03-15

    The Japan Atomic Energy Agency (JAEA) has an in-pile irradiation-assisted stress corrosion cracking (IASCC) test plan to evaluate in-situ effects of neutron/{gamma}-ray irradiation on crack growth of irradiated stainless steels under high-temperature water conditions for commercial boiling water reactors (BWRs) using the Japan Materials Testing Reactor (JMTR). Crack growth rate and its electrochemical corrosion potential (ECP) dependence are different between in-pile test and post irradiation examination (PIE), but these differences are not fully understood. The objectives of the present study are to understand the difference between in-pile and out-of-pile IASCC growth and to confirm the effectiveness of mitigation due to lowering ECP on in-pile crack growth rates. For in-pile crack growth tests, we have selected a large compact tension specimen such as 0.5T-CT because of validity of SCC growth test at a high stress intensity factor (K-value). For loading a 0.5T-CT specimen up to K - 30 MPa {radical}m, we have adopted a lever type loading unit for in-pile crack growth tests in the JMTR. In this report, an in-pile test plan for crack growth of irradiated SUS316L stainless steels under simulated BWR conditions in the JMTR and current status of development of in-pile crack growth test techniques are presented. (author)

  2. Analisis Unjuk Kerja Aplikasi VoIP Call Android di Jaringan MANET [Performance Analysis of VoIP Call Application Android in MANET (Mobile Ad Hoc Network

    Directory of Open Access Journals (Sweden)

    Ryan Ari Setyawan

    2015-06-01

    Full Text Available Penelitian ini bertujuan menganalisis kinerja aplikasi  VoIP call android di jaringan MANET (mobile ad hoc network.  Hasil pengujian menunjukan bahwa aplikasi VoIP call android dapat digunakan di jaringan MANET. Delay yang dihasilkan paling besar di pengujian indoor dengan jarak 11-15 meter yakni sebesar 0,014624811 seconds. Packet loss yang dihasilkan pada range 1%-2% sedangkan standar packet loss yang ditetapkan oleh CISCO untuk layanan aplikasi VoIP adalah < 5%. Jitter yang dihasilkan yakni antara 0,01-0,06 seconds sedangkan standar yang ditetapkan oleh CISCO adalah ≤ 30 ms atau 0,03 seconds. Throughput yang dihasilkan pada proses pengujian yakni antar 161 kbps-481 kbps. *****This study aims to analyze the performance of VOIP call android application in the MANET (mobile ad hoc network. The results showed that VoIP applications could be implemented in MANET network. The highest  delay is produced in indoor testing  with distance of 11-15 meters,  which is equal to 0.014624811 seconds. Packet loss is generated in the range of 1% -2%, while packet loss standards set by Cisco for VoIP application services are <5%. The jitter is between 0.01 to 0.06 seconds, while the standard set by CISCO is ≤ 30 ms or 0.03 seconds. Throughput generated in the testing process is between 161 kbps-481 kbps.

  3. Study on irradiation of freshening ginseng and toxicity test

    International Nuclear Information System (INIS)

    Wang Ziwen; Xu Dechun; Yang Wanqi

    1991-01-01

    The ginsengs irradiated by 1 or 2 kGy of γ-rays have been stored for 6 months under room temperature. Its freshening rates was 86.67% and 88.33% respectively. The saponin content was maintained. The irradiated ginsengs had the vigour of sap fully and beautiful colour. Therefore they can be stored much longer for sell. The toxicity test showed that there was no toxicity for irradiated ginsengs

  4. SUPER-FMIT, an accelerator-based neutron source for fusion components irradiation testing

    International Nuclear Information System (INIS)

    Burke, R.J.; Holmes, J.J.; Johnson, D.L.; Mann, F.M.; Miles, R.R.

    1984-01-01

    The SUPER-FMIT facility is proposed as an advanced accelerator based neutron source for high flux irradiation testing of large-sized fusion reactor components. The facility would require only small extensions to existing accelerator and target technology originally developed for the Fusion Materials Irradiation Test (FMIT) facility. There, neutrons would be produced by a 0.1 ampere beam of 35 MeV deuterons incident upon a liquid lithium target. The volume available for high flux (> 10 14 n/cm 2 -s) testing in SUPER-FMIT would be 14 liters, about a factor of 30 larger than in the FMIT facility. This is because the effective beam current of 35 MeV deuterons on target can be increased by a factor of ten to 1.0 amperes or more. Such a large increase can be accomplished by acceleration of multiple beams of molecular deuterium ions (D 2 +) to 70 MeV in a common accelerator sructure. The availability of multiple beams and large total current allows great variety in the testing that can be done. For example, fluxes greater than 10 16 n/cm 2 -s, multiple simultaneous experiments, and great flexibility in tailoring of spatial distributions of flux and spectra can be achieved

  5. Irradiation effects test series, test IE-5. Test results report. [PWR

    Energy Technology Data Exchange (ETDEWEB)

    Croucher, D. W.; Yackle, T. R.; Allison, C. M.; Ploger, S. A.

    1978-01-01

    Test IE-5, conducted in the Power Burst Facility at the Idaho National Engineering Laboratory, employed three 0.97-m long pressurized water reactor type fuel rods, fabricated from previously irradiated zircaloy-4 cladding and one similar rod fabricated from unirradiated cladding. The objectives of the test were to evaluate the influence of simulated fission products, cladding irradiation damage, and fuel rod internal pressure on pellet-cladding interaction during a power ramp and on fuel rod behavior during film boiling operation. The four rods were subjected to a preconditioning period, a power ramp to an average fuel rod peak power of 65 kW/m, and steady state operation for one hour at a coolant mass flux of 4880 kg/s-m/sup 2/ for each rod. After a flow reduction to 1800 kg/s-m/sup 2/, film boiling occurred on one rod. Additional flow reductions to 970 kg/s-m/sup 2/ produced film boiling on the three remaining fuel rods. Maximum time in film boiling was 80s. The rod having the highest initial internal pressure (8.3 MPa) failed 10s after the onset of film boiling. A second rod failed about 90s after reactor shutdown. The report contains a description of the experiment, the test conduct, test results, and results from the preliminary postirradiation examination. Calculations using a transient fuel rod behavior code are compared with the test results.

  6. Pollination with heavily irradiated pollen in Nicotiana: induced parthenogenesis and embryological study

    International Nuclear Information System (INIS)

    Musial, K.; Przywara, L.

    1999-01-01

    Nicotiana crosses were pollinated in situ and in vitro with heavily irradiated pollen (500, 700, 1000 Gy) to induce parthenogenesis and to study the development of embryo and endosperm. Haploids were obtained after in situ pollination only; however, parthenogenetic proembryos occurred also after in vitro pollination. It was demonstrated that ovule culture following pollination offers a better chance to produce haploids than undisturbed pollination does. Pollination with irradiated pollen (PwIP) stron gly decreased the number of endosperm cells and the size of embryo sacs, and it affected the development of embryos; no significant differences between applied irradiation doses were found. Ovules with endosperm only, embryo only, and with both embryo and endosperm were observed. The most frequent were the ovules with endosperm only, the rarest with embryo only. A small amount of storage products occurred in the endosperm cells. The diploid chromosome number counted in the endosperm produced after PwIP points to their origin without fertilization. An interesting phenomenon observed after PwIP was vigorous growth of endothelium. (author)

  7. Vitamin D Status in Chronic Kidney Disease - UVB Irradiation Is Superior to Oral Supplementation.

    Science.gov (United States)

    Krause, Rolfdieter; Roth, Heinz Jürgen; Kaase, Heinrich; Stange, Rainer; Holick, Michael F

    2016-03-01

    In chronic kidney disease (CKD) a deficiency of 1,25-dihydroxyvitamin D is common. The aim of this review was to compare vitamin D status after oral supplementation of vitamin D3 to that of serial suberythemal irradiation in end-stage kidney disease (ESKD) patients. Ninety-five patients, with a mean age of 62 (range=35-82) years, were treated with a mean dose of 35,000 (20,000-60,000) IU vitamin D3 per week for a period of 18 months. Fourteen patients, with a mean age of 51 (range=41-57) years, were whole-body UVB irradiated for over 6 months. From 3 hemodialysis patients skin biopsies were performed. With oral supplementation 25(OH)D3 increased by 60%. With UV irradiation 25(OH)D3 increased by 400%. Gene expression analysis demonstrated an improvement in the vitamin D receptor (VDR) by 0.65 fold, in 1-alpha-hydroxylase (CYP27B1) by 1.0 fold, and in 25-hydroxylase (CYP2R) by 1.2 fold. Serial suberythemal UVB irradiation of patients with CKD on dialysis is capable to improve serum 25(OH)D3 and 1,25(OH)2D3 by enhancing the skin's ability to activate vitamin D. Copyright© 2016 International Institute of Anticancer Research (Dr. John G. Delinassios), All rights reserved.

  8. Security Analysis System to Detect Threats on a SIP VoIP Infrasctructure Elements

    Directory of Open Access Journals (Sweden)

    Filip Rezac

    2011-01-01

    Full Text Available SIP PBX is definitely the alpha and omega of any IP telephony infrastructure and frequently also provides other services than those related to VoIP traffic. These exchanges are, however, very often the target of attacks by external actors. The article describes a system that was developed on VSB-TU Ostrava as a testing tool to verify if the target VoIP PBX is adequately secured and protected against any real threats. The system tests the SIP element for several usually occurring attacks and it compiles evaluation of its overall security on the basis of successfully or unsuccessfully penetrations. The article describes the applications and algorithms that are used by system and the conclusion consists recommendations and guidelines to ensure effective protection against VoIP PBX threats. The system is designed as an open-source web application, thus allowing independent access and is fully extensible to other test modules.

  9. Structural safety test and analysis of type IP-2 transport packages with bolted lid type and thick steel plate for radioactive waste drums in a NPP

    International Nuclear Information System (INIS)

    Kim, Dong Hak; Seo, Ki Seog; Lee, Sang Jin; Lee, Kyung Ho; Kim, Jeong Mook

    2007-01-01

    If a type IP-2 transport package were to be subjected to a free drop test and a penetration test under the normal conditions of transport, it should prevent a loss or dispersal of the radioactive contents and a more than 20% increase in the maximum radiation level at any external surface of the package. In this paper, we suggested the analytic method to evaluate the structural safety of a type IP-2 transport package using a thick steel plate for a structure part and a bolt for tying a bolt. Using an analysis a loss or disposal of the radioactive contents and a loss of shielding integrity were confirmed for two kinds of type IP-2 transport packages to transport radioactive waste drums from a waste facility to a temporary storage site in a nuclear power plant. Under the free drop condition the maximum average stress at the bolts and the maximum opening displacement of a lid were compared with the tensile stress of a bolt and the steps in a lid, which were made to avoid a streaming radiation in the shielding path, to evaluate a loss or dispersal of radioactive waste contents. Also a loss of shielding integrity was evaluated using the maximum decrease in a shielding thickness. To verify the impact dynamic analysis for free drop test condition and evaluate experimentally the safety of two kinds of type IP-2 transport packages, free drop tests were conducted with various drop directions

  10. Metallographic analysis of irradiated RERTR-3 fuel test specimens

    International Nuclear Information System (INIS)

    Meyer, M. K.; Hofman, G. L.; Strain, R. V.; Clark, C. R.; Stuart, J. R.

    2000-01-01

    The RERTR-3 irradiation test was designed to investigate the irradiation behavior of aluminum matrix U-MO alloy dispersion fuels under high-temperature, high-fission-rate conditions. Initial postirradiation examination of RERTR-3 fuel specimens has concentrated on binary U-MO atomized fuels. The rate of matrix aluminum depletion was found to be higher than predictions based on low temperature irradiation data. Wavelength Dispersive X-ray Spectroscopy (WDS) indicates that aluminum is present in the interior of the fuel particles. WDS data is supported by a mass and volume balance calculation performed on the basis of image analysis results. The depletion of matrix aluminum seems to have no detrimental effects on fuel performance under the conditions tested to date

  11. A small animal image guided irradiation system study using 3D dosimeters

    International Nuclear Information System (INIS)

    Qian, Xin; Wuu, Cheng-Shie; Admovics, John

    2015-01-01

    In a high resolution image-guided small animal irradiation platform, a cone beam computed tomography (CBCT) is integrated with an irradiation unit for precise targeting. Precise quality assurance is essential for both imaging and irradiation components. The conventional commissioning techniques with films face major challenges due to alignment uncertainty and labour intensive film preparation and scanning. In addition, due to the novel design of this platform the mouse stage rotation for CBCT imaging is perpendicular to the gantry rotation for irradiation. Because these two rotations are associated with different mechanical systems, discrepancy between rotation isocenters exists. In order to deliver x-ray precisely, it is essential to verify coincidence of the imaging and the irradiation isocenters. A 3D PRESAGE dosimeter can provide an excellent tool for checking dosimetry and verifying coincidence of irradiation and imaging coordinates in one system. Dosimetric measurements were performed to obtain beam profiles and percent depth dose (PDD). Isocentricity and coincidence of the mouse stage and gantry rotations were evaluated with starshots acquired using PRESAGE dosimeters. A single PRESAGE dosimeter can provide 3 -D information in both geometric and dosimetric uncertainty, which is crucial for translational studies

  12. IPs

    African Journals Online (AJOL)

    Fr. Ikenga

    special rights to the under-privileged IPs based on their culture, religion and .... and exploitation of natural resources, political determination and autonomy, .... supportive and sustaining.33Balancing individualism and communalism will avoid ...

  13. AGR-2 irradiation test final as-run report, Rev. 1

    International Nuclear Information System (INIS)

    2014-01-01

    This document presents the as-run analysis of the AGR-2 irradiation experiment. AGR-2 is the second of the planned irradiations for the Advanced Gas Reactor (AGR) Fuel Development and Qualification Program. Funding for this program is provided by the U.S. Department of Energy as part of the Very High Temperature Reactor (VHTR) Technical Development Office (TDO) program. The objectives of the AGR-2 experiment are to: (a) Irradiate UCO (uranium oxycarbide) and UO 2 (uranium dioxide) fuel produced in a large coater. Fuel attributes are based on results obtained from the AGR-1 test and other project activities; (b) Provide irradiated fuel samples for post-irradiation experiment (PIE) and safety testing; and, (c) Support the development of an understanding of the relationship between fuel fabrication processes, fuel product properties, and irradiation performance. The primary objective of the test was to irradiate both UCO and UO 2 TRISO (tri-structural isotropic) fuel produced from prototypic scale equipment to obtain normal operation and accident condition fuel performance data. The UCO compacts were subjected to a range of burnups and temperatures typical of anticipated prismatic reactor service conditions in three capsules. The test train also includes compacts containing UO 2 particles produced independently by the United States, South Africa, and France in three separate capsules. The range of burnups and temperatures in these capsules were typical of anticipated pebble bed reactor service conditions. The results discussed in this report pertain only to U.S. produced fuel. In order to achieve the test objectives, the AGR-2 experiment was irradiated in the B-12 position of the Advanced Test Reactor (ATR) at Idaho National Laboratory (INL) for a total irradiation duration of 559.2 effective full power days (EFPD). Irradiation began on June 22, 2010, and ended on October 16, 2013, spanning 12 ATR power cycles and approximately three and a half calendar years. The

  14. AGR-2 Irradiation Test Final As-Run Report, Rev 2

    Energy Technology Data Exchange (ETDEWEB)

    Collin, Blaise P. [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2014-08-01

    This document presents the as-run analysis of the AGR-2 irradiation experiment. AGR-2 is the second of the planned irradiations for the Advanced Gas Reactor (AGR) Fuel Development and Qualification Program. Funding for this program is provided by the U.S. Department of Energy as part of the Very High Temperature Reactor (VHTR) Technical Development Office (TDO) program. The objectives of the AGR-2 experiment are to: (a) Irradiate UCO (uranium oxycarbide) and UO2 (uranium dioxide) fuel produced in a large coater. Fuel attributes are based on results obtained from the AGR-1 test and other project activities. (b) Provide irradiated fuel samples for post-irradiation experiment (PIE) and safety testing. (c) Support the development of an understanding of the relationship between fuel fabrication processes, fuel product properties, and irradiation performance. The primary objective of the test was to irradiate both UCO and UO2 TRISO (tri-structural isotropic) fuel produced from prototypic scale equipment to obtain normal operation and accident condition fuel performance data. The UCO compacts were subjected to a range of burnups and temperatures typical of anticipated prismatic reactor service conditions in three capsules. The test train also includes compacts containing UO2 particles produced independently by the United States, South Africa, and France in three separate capsules. The range of burnups and temperatures in these capsules were typical of anticipated pebble bed reactor service conditions. The results discussed in this report pertain only to U.S. produced fuel. In order to achieve the test objectives, the AGR-2 experiment was irradiated in the B-12 position of the Advanced Test Reactor (ATR) at Idaho National Laboratory (INL) for a total irradiation duration of 559.2 effective full power days (EFPD). Irradiation began on June 22, 2010, and ended on October 16, 2013, spanning 12 ATR power cycles and approximately three and a

  15. Offloading IP Flows onto Lambda-Connections

    NARCIS (Netherlands)

    Fioreze, Tiago; Oude Wolbers, Mattijs; van de Meent, R.; Pras, Aiko

    2007-01-01

    Optical networks are capable of switching IP traffic via lambda connections. In this way, big IP flows that overload the regular IP routing level may be moved to the optical level, where they get better Quality of Service (QoS). At the same time, the IP routing level is off-loaded and can serve

  16. Pre-irradiation tests on U-Si alloys

    International Nuclear Information System (INIS)

    Howe, L.M.; Bell, L.G.

    1958-05-01

    Pre-irradiation tests of hardness, density, electrical resistivity, and corrosion resistance as well as metallographic and X-ray examinations were undertaken on U-Si core material, which had been co-extruded in Zr--2, in order that the effect of irradiation on alloys in the epsilon range could be assessed. In addition, a study of the epsilonization of arc-melted material was undertaken in order to rain familiarity with the epsilonization process and to obtain information on the corrosion behaviour of epsilonized material. Sheathed U-Si samples in the epsilonized and de-epsilonized conditions have been irradiated in the X-2 loop, with a water temperature of 275 o C. The samples have been examined after 250 MWD/Tonne and show no dimensional change. (author)

  17. Summary of the Minor Actinide-bearing MOX AFC-2C and -2D Irradiations

    International Nuclear Information System (INIS)

    McClellan, Kenneth; Chichester, Heather; Hayes, Steve; Voit, Stewart

    2013-01-01

    Summary of AFC-2C and AFC-2D tests: • AFC-2C and 2D, 1st MOX experiments in FCRD, were irradiated in ATR; • Initial results indicate performance of experimental MA-MOX fuels are similar to standard FR MOX fuels; • Cd-shrouded ATR experiment assembly and 235 U enrichment produce prototypic fast reactor power and temperature profiles leading to classic MOX zone restructuring; • Baseline postirradiation examinations have been completed for AFC-2C MOX and MA-MOX fuels; • Future work includes: – PIE of AFC-2D; – compare results to prototypic MOX fuel performance; – electron microscopy for microstructure and constituent distribution; – advanced NDE on saved pins

  18. Mobile IP: Security & application

    NARCIS (Netherlands)

    Tuquerres, G.; Salvador, M.R.; Sprenkels, Ron

    1999-01-01

    As required in the TGS Mobile IP Advanced Module, this paper presents a survey of common security threats which mobile IP networks are exposed to as well as some proposed solutions to deal with such threats.

  19. Voice over IP Security

    CERN Document Server

    Keromytis, Angelos D

    2011-01-01

    Voice over IP (VoIP) and Internet Multimedia Subsystem technologies (IMS) are rapidly being adopted by consumers, enterprises, governments and militaries. These technologies offer higher flexibility and more features than traditional telephony (PSTN) infrastructures, as well as the potential for lower cost through equipment consolidation and, for the consumer market, new business models. However, VoIP systems also represent a higher complexity in terms of architecture, protocols and implementation, with a corresponding increase in the potential for misuse. In this book, the authors examine the

  20. Education and training by utilizing irradiation test reactor simulator

    International Nuclear Information System (INIS)

    Eguchi, Shohei; Koike, Sumio; Takemoto, Noriyuki; Tanimoto, Masataka; Kusunoki, Tsuyoshi

    2016-01-01

    The Japan Atomic Energy Agency, at its Japan Materials Testing Reactor (JMTR), completed an irradiation test reactor simulator in May 2012. This simulator simulates the operation, irradiation test, abnormal transient change during operation, and accident progress events, etc., and is able to perform operation training on reactor and irradiation equipment corresponding to the above simulations. This simulator is composed of a reactor control panel, process control panel, irradiation equipment control panel, instructor control panel, large display panel, and compute server. The completed simulator has been utilized in the education and training of JMTR operators for the purpose of the safe and stable operation of JMTR and the achievement of high operation rate after resuming operation. For the education and training, an education and training curriculum has been prepared for use in not only operation procedures at the time of normal operation, but also learning of fast and accurate response in case of accident events. In addition, this simulator is also being used in operation training for the purpose of contributing to the cultivation of human resources for atomic power in and out of Japan. (A.O.)

  1. High gamma-rays irradiation tests of critical components for ITER (International Thermonuclear Experimental Reactor) in-vessel remote handling system

    International Nuclear Information System (INIS)

    Obara, Kenjiro; Kakudate, Satoshi; Oka, Kiyoshi

    1999-02-01

    In ITER, the in-vessel remote handling is inevitably required to assemble and maintain the activated in-vessel components due to deuterium and tritium operation. Since the in-vessel remote handling system has to be operated under the intense of gamma ray irradiation, the components of the remote handling system are required to have radiation hardness so as to allow maintenance operation for a sufficient length of time under the ITER in-vessel environments. For this, the Japan, European and Russian Home Teams have extensively conducted gamma ray irradiation tests and quality improvements including optimization of material composition through ITER R and D program in order to develop radiation hard components which satisfy the doses from 10 MGy to 100 MGy at a dose rate of 1 x 10 6 R/h (ITER R and D Task: T252). This report describes the latest status of radiation hard component development which has been conducted by the Japan Home Team in the ITER R and D program. The number of remote handling components tested is about seventy and these are categorized into robotics (Subtask 1), viewing system (Subtask 2) and common components (Subtask 3). The irradiation tests, including commercial base products for screening, modified products and newly developed products to improve the radiation hardness, were carried out using the gamma ray irradiation cells in Takasaki Establishment, JAERI. As a result, the development of the radiation hard components which can be tolerable for high temperature and gamma radiation has been well progressed, and many components, such as AC servo motor with ceramics insulated wire, optical periscope and CCD camera, have been newly developed. (author)

  2. High gamma-rays irradiation tests of critical components for ITER (International Thermonuclear Experimental Reactor) in-vessel remote handling system

    Energy Technology Data Exchange (ETDEWEB)

    Obara, Kenjiro; Kakudate, Satoshi; Oka, Kiyoshi [Department of Fusion Engineering Research, Naka Fusion Research Establishment, Japan Atomic Energy Research Institute, Naka, Ibaraki (Japan)] [and others

    1999-02-01

    In ITER, the in-vessel remote handling is inevitably required to assemble and maintain the activated in-vessel components due to deuterium and tritium operation. Since the in-vessel remote handling system has to be operated under the intense of gamma ray irradiation, the components of the remote handling system are required to have radiation hardness so as to allow maintenance operation for a sufficient length of time under the ITER in-vessel environments. For this, the Japan, European and Russian Home Teams have extensively conducted gamma ray irradiation tests and quality improvements including optimization of material composition through ITER R and D program in order to develop radiation hard components which satisfy the doses from 10 MGy to 100 MGy at a dose rate of 1 x 10{sup 6} R/h (ITER R and D Task: T252). This report describes the latest status of radiation hard component development which has been conducted by the Japan Home Team in the ITER R and D program. The number of remote handling components tested is about seventy and these are categorized into robotics (Subtask 1), viewing system (Subtask 2) and common components (Subtask 3). The irradiation tests, including commercial base products for screening, modified products and newly developed products to improve the radiation hardness, were carried out using the gamma ray irradiation cells in Takasaki Establishment, JAERI. As a result, the development of the radiation hard components which can be tolerable for high temperature and gamma radiation has been well progressed, and many components, such as AC servo motor with ceramics insulated wire, optical periscope and CCD camera, have been newly developed. (author)

  3. Post-Irradiation Examination Test of the Parts of X-Gen Nuclear Fuel Assembly

    International Nuclear Information System (INIS)

    Ahn, S. B.; Ryu, W. S.; Choo, Y. S.

    2008-08-01

    The mechanical properties of the parts of a nuclear fuel assembly are degraded during the operation of the reactor, through the mechanism of irradiation damage. The properties changes of the parts of the fuel assembly should be quantitatively estimated to ensure the safety of the fuel assembly and rod during the operation. The test techniques developed in this report are used to produce the irradiation data of the grid 1x1 cell spring, the grid 1x1 cell, the spring on one face of the 1x1 cell, the inner/outer strip of the grid and the welded part. The specimens were irradiated in the CT test hole of HANARO of a 30 MW thermal output at 300 deg. C during about 100 days From the spring test of mid grid 1x1 cell and grid plate, the irradiation effects can be examined. The irradiation effects on the irradiation growth also were occurred. The buckling load of mid grid 1x1 cell does not change with a neutron irradiation. From the tensile tests, the strengths increased but the elongations decreased due to an irradiation. The tensile test and microstructure examination of the spot and fillet welded parts are performed for the evaluation of an irradiation effects. Through these tests of components, the essential data on the fuel assembly design could be obtained. These results will be used to update the irradiation behavior databases, to improve the performance of fuel assembly, and to predict the service life of the fuel assembly in a reactor

  4. Water accelerated transformation of d-limonene induced by ultraviolet irradiation and air exposure.

    Science.gov (United States)

    Li, Li Jun; Hong, Peng; Jiang, Ze Dong; Yang, Yuan Fan; Du, Xi Ping; Sun, Hao; Wu, Li Ming; Ni, Hui; Chen, Feng

    2018-01-15

    d-Limonene is a fragrant chemical that widely exists in aromatic products. Isotopic labelling of water molecules plus GC-MS and GC-PCI-Q-TOF analyses were used to investigate the influence of water molecules on chemical transformation of d-limonene induced by UV irradiation and air exposure. The results showed that the synergistic effect of UV irradiation, air exposure and water presence could facilitate d-limonene transformation into the limonene oxides: p-mentha-2,8-dienols, hydroperoxides, carveols, l-carvone and carvone oxide. UV irradiation, air exposure, or water alone, however, caused negligible d-limonene transformation. With the aid of isotopic labelling of water and oxygen molecules, it was found that water molecules were split into hydrogen radicals and hydroxyl radicals, and the hydrogen radicals, in particular, promoted the transformation reactions. This study has elucidated the mechanism and factors that influence the transformation of d-limonene, which will benefit industries involved in production and storage of d-limonene-containing products. Copyright © 2017 Elsevier Ltd. All rights reserved.

  5. Development of post-irradiation test facility for domestic production of 99Mo

    International Nuclear Information System (INIS)

    Taguchi, Taketoshi; Yonekawa, Minoru; Kato, Yoshiaki; Kurosawa, Makoto; Nishikata, Kaori; Ishida, Takuya; Kawamata, Kazuo

    2013-01-01

    JMTR focus on the activation method. By carrying out the preliminary tests using irradiation facilities existing, and verification tests using the irradiation facility that has developed in the cutting-edge research and development strategic strengthening business, as irradiation tests towards the production of 99 Mo, we have been conducting research and development that can contribute to supply about 25% for 99 Mo demand in Japan and the stable supply of radiopharmaceutical. This report describes a summary of the status of the preliminary tests for the production of 99 Mo: Maintenance of test equipment in the facility in JMTR hot laboratory in preparation for research and development for the production of 99 Mo in JMTR and using MoO 3 pellet irradiated at Kyoto University Research Reactor Institute (KUR). (author)

  6. Challenges Regarding IP Core Functional Reliability

    Science.gov (United States)

    Berg, Melanie D.; LaBel, Kenneth A.

    2017-01-01

    For many years, intellectual property (IP) cores have been incorporated into field programmable gate array (FPGA) and application specific integrated circuit (ASIC) design flows. However, the usage of large complex IP cores were limited within products that required a high level of reliability. This is no longer the case. IP core insertion has become mainstream including their use in highly reliable products. Due to limited visibility and control, challenges exist when using IP cores and subsequently compromise product reliability. We discuss challenges and suggest potential solutions to critical application IP insertion.

  7. Estimation of γ irradiation induced genetic damage by Ames test

    International Nuclear Information System (INIS)

    Hosoda, Eiko

    1999-01-01

    Mutation by 60 Co γ irradiation was studied in five different histidine-requiring auxotrophs of Salmonella typhimurium. The strains TA98 (sensitive to frameshift) and TA100 (sensitive to base-pair substitution) were irradiated (10-84 Gy and 45-317 Gy, respectively) and revertants were counted. TA98 exhibited radiation-induced revertants, 2.8 fold of spontaneous revertants, although no significant increase was detected in TA100. Then, three other frameshift-sensitive strains TA1537, TA1538 and TA94 were irradiated in a dose of 61-167 Gy. Only in TA94, revertants increased 3.5 fold. Since spontaneous revertants are known to be independent of cell density, a decrease of bacterial number by γ irradiation was confirmed not to affect the induced revertants by dilution test. Thus the standard Ames Salmonella assay identified γ irradiation was confirmed not to affect the induced revertants by dilution test. Thus the standard Ames Salmonella assay identified γ irradiation as a mutagenetic agent. The mutagenicity of dinitropyrene, a mutagen widely existing in food, and dismutagenicity of boiling water insoluble fraction of Hizikia fusiforme, edible marine alga, were tested on γ induced revertant formation in TA98 and TA94. Dinitropyrene synergistically increased γ induced revertants and Hizikia insoluble fraction reduced the synergistic effect of dinitropyrene dependently on the concentration. (author)

  8. IP Infrastructure Geolocation

    Science.gov (United States)

    2015-03-01

    by non-commercial enti- ties. HostiP is a community-driven geolocation service. It provides an Application Pro- gramming Interface ( API ) for...NAVAL POSTGRADUATE SCHOOL MONTEREY, CALIFORNIA THESIS IP INFRASTRUCTURE GEOLOCATION Thesis Advisor: Second Reader: by Guan Yan Cai March...FUNDING NUMBERS IP INFRASTRUCfURE GEOLOCATION N66001-2250-59231 6. AUTHOR(S) Guan Yan Cai 7. PERFORMING ORGANIZATION NAME(S) AND AOORESS(ES) 9

  9. Identification of gamma irradiated apples by the half-embryo test

    International Nuclear Information System (INIS)

    Miranda, Gabriel C.; Bujan, Alfonso; Leiva, Carlos H.; Yusef, Maria V.

    2003-01-01

    The half-embryo test was applied to irradiated apples (var. Red delicious).The irradiation of apples caused obvious changes in the growth of the half-embryo. A dose of 100 Gy or more, inhibits the epicotyl development and with 50 Gy dose is possible to observe a great contrast with the non-irradiated apples. If the epicotyl development is less than 4 cm., the apples are identified as irradiated. The assessment can be made after 7 days. (author)

  10. Study of the stability of the tragacanto rubber irradiated

    International Nuclear Information System (INIS)

    Rodriguez, M.; Romero, M.; Montes de Oca, N.

    2001-01-01

    Presently work was studied the processing by radiations of the tragacanto rubber powdered, with ends of achieving its sterilization. For the irradiation, the envelopes were placed in aluminum containers to reason of an envelope for container. The material underwent analysis of its viscosity and microbiological tests. They got ready solutions, according to the British pharmacopoeia, starting from the material irradiated with dose of D0-0, D1-5, D2-7.5, and D3-10 kGy. The smaller than the applied doses (5kGy) it produced a variation of 72% in the viscosity of the solutions, in comparison with the rubber without irradiating. They were carried out tests of sterility to the material irradiated with inferior dose of 5 kGy, being contaminated in all the cases

  11. GfW-handbook for irradiation test guidelines for radiation hardness of electronic components

    International Nuclear Information System (INIS)

    Braeunig, D.; Wulf, F.; Gaebler, W.; Boden, A.

    1982-12-01

    The purpose of the report is to propose irradiation test methods so that a standardized application of the methods can lead to a better comparison of test results. The interaction of different radiation species with matter - ionization and displacement - is described. Application of appropriate radiation sources, dosimetry problems, and shielding for simulating space radiation effects by laboratory testing is discussed. The description and characteristics of the irradiation sources are presented. Flowcharts of the planning and running of irradiation tests are given. Guidelines for running the tests are established, test methods and test circuits are proposed. The test system offers the capability of measuring devices also of high complexity up to microprocessors. The test results are collected regularly and are published in GfW-Handbook TN53/08, 'Data Compilation of Irradiation Tested Electronic Components'. (orig./HP) [de

  12. Quality engineering in FFTF irradiation tests

    International Nuclear Information System (INIS)

    Caplinger, W.H.

    1980-01-01

    The design and fabrication of an irradiation test for the Fast Flux Test Facility are planned, controlled and documented in accordance with the Department of Energy standards. Tests built by Westinghouse Hanford Company are further controlled and guided by a series of increasingly specific documents, including guidelines for program control, procedures for engineering operations, standard practices and detailed operating procedures. In response to this guidance, a series of five documents is prepared covering each step of the experiment from conception through fabrication and assembly. This paper describes the quality assurance accompanying these five steps

  13. Short-term carcinogenicity testing of a potent murine intestinal mutagen, 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine (PhIP), in Apc1638N transgenic mice

    DEFF Research Database (Denmark)

    Sørensen, Ilona Kryspin; Kristiansen, E.; Mortensen, Alicja

    1997-01-01

    others, mammary tumors, We have studied these mice in a short-term carcinogenicity test with 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine (PhIP), a potent murine small intestinal mutagen and lymphomagen. Upon dietary administration of 0.03% PhIP in a short-term (6 months) study, a significantly...

  14. Irradiation of head-and-neck tumors with intensity modulated radiotherapy (IMRT). Comparison between two IMRT techniques with 3D conformal irradiation

    International Nuclear Information System (INIS)

    Heeger, Jonas

    2013-01-01

    For 12 patients with inoperable head-neck carcinoma that were treated with 3D conformal irradiation techniques additional irradiation plans using IMRT were developed. It was shown that the IMRT techniques are superior to the 3D conformal technique. The new rapid arc technique is unclear with respect to the critical organs (parotid glands, spinal canal and mandibles) but is significantly advantageous for the other normal tissue with respect to conformity (steeper dose gradients) and thus radiation dose reduction. The resulting lower irradiation time and the reduced radiation exposure being important for the treatment economy and patients' comfort should favor the more planning intensive rapid arc technique.

  15. Irradiation and examination results of the AC-3 mixed-carbide test

    International Nuclear Information System (INIS)

    Mason, R.E.; Hoth, C.W.; Stratton, R.W.; Botta, F.

    1992-01-01

    The AC-3 test was a cooperative Swiss/US irradiation test of mixed-carbide, (U,Pr)C, fuel pins in the Fast Flux Test Facility. The test included 25 Swiss-fabricated sphere-pac-type fuel pins and 66 U.S. fabricated pellet-type fuel pins. The test was designed to operate at prototypical fast reactor conditions to provide a direct comparison of the irradiation performance of the two fuel types. The test design and fuel fabrication processes used for the AC-3 test are presented

  16. Protective effect of alkali extract of Huangmo (AEHM) on immunological function in X-irradiated mice

    International Nuclear Information System (INIS)

    Ye Fei; Wu Congmei; Su Shijie; Cao Ruimin

    1996-01-01

    The male mice were given ip AEHM 5 mg/kg, wt/d before irradiation with 2.0 Gy X-rays for 3 days, and the changes of several immunological indexes were observed 24 h after X-irradiation. The results showed that AEHM significantly increased the numbers of splenocytes and thymocytes, the reaction of splenocytes to ConA and the spontaneous proliferation of thymocytes in irradiated mice, and decreased the fall of spleen and thymus. In addition, a tendency of the increases in the above indexes in the intact mice treated with AEHM was observed. Meanwhile, AEHM possessed similar radioprotective effect on immunological functions to polysaccharides of Ginseng. The results suggest that AEHM has not only a radioprotective effect on immunological functions in the irradiated mice, but also an enhancing effect on the defence functions in the intact mice. It is very hopeful that AEHM acted as immune-enhanced drug should be used in the clinic

  17. Mobile-ip Aeronautical Network Simulation Study

    Science.gov (United States)

    Ivancic, William D.; Tran, Diepchi T.

    2001-01-01

    NASA is interested in applying mobile Internet protocol (mobile-ip) technologies to its space and aeronautics programs. In particular, mobile-ip will play a major role in the Advanced Aeronautic Transportation Technology (AATT), the Weather Information Communication (WINCOMM), and the Small Aircraft Transportation System (SATS) aeronautics programs. This report presents the results of a simulation study of mobile-ip for an aeronautical network. The study was performed to determine the performance of the transmission control protocol (TCP) in a mobile-ip environment and to gain an understanding of how long delays, handoffs, and noisy channels affect mobile-ip performance.

  18. Yields of 2-deoxy-D-gluconic, D-gluconic and other sugar acids in gamma-irradiated aqueous solutions of D-glucose. [Gamma rays

    Energy Technology Data Exchange (ETDEWEB)

    Esterbauer, H; Schubert, J; Sanders, E B; Sweeley, C C [Pittsburgh Univ., Pa. (USA); Michigan State Univ., East Lansing (USA). Dept. of Biochemistry)

    1977-03-01

    The yields of 2-deoxy-D-gluconic, D-gluconic and other sugar acids from /sup 60/Co-gamma irradiated (dose-rate = 4 Krads/min) D-glucose solutions are reported. The acids produced upon radiolysis were separated from glucose and neutral products by anion exchange, assayed by gas chromatography of the trimethylsilyl derivatives, and definitive identification made by mass spectrometry. In He degassed, irradiated 0.055 M glucose G(2-deoxy-D-gluconic acid) = 0.62 and G(D-gluconic acid) = 0.20. The approximate G values for the other identified acids are: glyceric acid 0.03, 2-deoxy-tetronic acid 0.04, tetronic acid 0.03, 4-deoxypentonic acid 0.02, deoxyketogluconic acid 0.17. In N/sub 2/O saturated glucose solutions D-gluconic acid yields increased by a factor of approximately 1.9 while that of 2-deoxy-D-gluconic acid increased by a factor of only approximately 1.1.

  19. Experimental data report for Test TS-2 reactivity initiated accident test in NSRR with pre-irradiated BWR fuel rod

    International Nuclear Information System (INIS)

    Nakamura, Takehiko; Yoshinaga, Makio; Sobajima, Makoto; Fujishiro, Toshio; Kobayashi, Shinsho; Yamahara, Takeshi; Sukegawa, Tomohide; Kikuchi, Teruo

    1993-02-01

    This report presents experimental data for Test TS-2 which was the second test in a series of Reactivity Initiated Accident (RIA) condition test using pre-irradiated BWR fuel rods, performed at the Nuclear Safety Research Reactor (NSRR) in February, 1990. Test fuel rod used in the Test TS-2 was a short sized BWR (7x7) type rod which was fabricated from a commercial rod irradiated at Tsuruga Unit 1 power reactor. The fuel had an initial enrichment of 2.79% and a burnup of 21.3Gwd/tU (bundle average). A pulse irradiation of the test fuel rod was performed under a cooling condition of stagnant water at atmospheric pressure and at ambient temperature which simulated a BWR's cold start-up RIA event. The energy deposition of the fuel rod in this test was evaluated to be 72±5cal/g·fuel (66±5cal/g·fuel in peak fuel enthalpy) and no fuel failure was observed. Descriptions on test conditions, test procedures, transient behavior of the test rod during the pulse irradiation, and, results of pre and post pulse irradiation examinations are described in this report. (author)

  20. Flexural strength of proof-tested and neutron-irradiated silicon carbide

    Science.gov (United States)

    Price, R. J.; Hopkins, G. R.

    1982-08-01

    Proof testing before service is a valuable method for ensuring the reliability of ceramic structures. Silicon carbide has been proposed as a very low activation first-wall and blanket structural material for fusion devices, where it would experience a high flux of fast neutrons. Strips of three types of silicon carbide were loaded in four-point bending to a stress sufficient to break about a third of the specimens. Groups of 16 survivors were irradiated to 2 × 10 26n/ m2 ( E>0.05 MeV) at 740°C and bend tested to failure. The strength distribution of chemically vapor-deposited silicon carbide (Texas Instruments) was virtually unchanged by irradiation. The mean strength of sintered silicon carbide (Carborundum Alpha) was reduced 34% by irradiation, while the Weibull modulus and the truncated strength distribution characteristic of proof-tested material were retained. Irradiation reduced the mean strength of reaction-bonded silicon carbide (Norton NC-430) by 58%, and the spread in strength values was increased. We conclude that for the chemically vapor-deposited and the sintered silicon carbide the benefits of proof testing to eliminate low strength material are retained after high neutron exposures.

  1. NRI experimental facility for the testing of irradiation assisted stress corrosion cracking

    International Nuclear Information System (INIS)

    Ruscak, M.; Chvatal, P.; Zamboch, M.

    1998-01-01

    IASCC influencing reactor internals of both BWR and PWR reactors is a complex phenomenon covering influences of material structure, neutron fluence, neutron flux, chemistry of environment, gamma radiation and mechanical stress. To evaluate such degradation, tests should be performed under conditions similar to those in real structure. Nuclear Research Institute has built several experimental facilities in order to be able to test IASCC degradation of materials. Basically, reactor water loops, both PWR and BWR, could be used to model environmental conditions including gamma and neutron irradiation. Pre-irradiation can be done in irradiation channels under well controlled temperature conditions. During the experiment, in-pile conditions can be compared with those out of pile. It enables to clarify pure influence of irradiation. For testing of irradiated specimens, hot cell facility has been developed for slow strain rate tests. The paper will show all above mentioned facilities as well as some of the results observed with them. (author)

  2. Irradiation Tests Supporting LEU Conversion of Very High Power Research Reactors in the US

    Energy Technology Data Exchange (ETDEWEB)

    Woolstenhulme, N. E.; Cole, J. I.; Glagolenko, I.; Holdaway, K. K.; Housley, G. K.; Rabin, B. H.

    2016-10-01

    The US fuel development team is developing a high density uranium-molybdenum alloy monolithic fuel to enable conversion of five high-power research reactors. Previous irradiation tests have demonstrated promising behavior for this fuel design. A series of future irradiation tests will enable selection of final fuel fabrication process and provide data to qualify the fuel at moderately-high power conditions for use in three of these five reactors. The remaining two reactors, namely the Advanced Test Reactor and High Flux Isotope Reactor, require additional irradiation tests to develop and demonstrate the fuel’s performance with even higher power conditions, complex design features, and other unique conditions. This paper reviews the program’s current irradiation testing plans for these moderately-high irradiation conditions and presents conceptual testing strategies to illustrate how subsequent irradiation tests will build upon this initial data package to enable conversion of these two very-high power research reactors.

  3. FMIT - the fusion materials irradiation test facility

    International Nuclear Information System (INIS)

    Liska, D.J.

    1980-01-01

    A joint effort by the Hanford Engineering Development Laboratory (HEDL) and Los Alamos Scientific Laboratory (LASL) has produced a preliminary design for a Fusion Materials Irradiation Test Facility (FMIT) that uses a high-power linear accelerator to fire a deuteron beam into a high-speed jet of molten lithium. The result is a continuous energy spectrum of neutrons with a 14-MeV average energy which can irradiate material samples to projected end-of-life levels in about 3 years, with a total accumulated fluence of 10 21 to 10 22 n/cm 2

  4. Subtype-selective regulation of IP(3) receptors by thimerosal via cysteine residues within the IP(3)-binding core and suppressor domain.

    Science.gov (United States)

    Khan, Samir A; Rossi, Ana M; Riley, Andrew M; Potter, Barry V L; Taylor, Colin W

    2013-04-15

    IP(3)R (IP(3) [inositol 1,4,5-trisphosphate] receptors) and ryanodine receptors are the most widely expressed intracellular Ca(2+) channels and both are regulated by thiol reagents. In DT40 cells stably expressing single subtypes of mammalian IP(3)R, low concentrations of thimerosal (also known as thiomersal), which oxidizes thiols to form a thiomercurylethyl complex, increased the sensitivity of IP(3)-evoked Ca(2+) release via IP(3)R1 and IP(3)R2, but inhibited IP(3)R3. Activation of IP(3)R is initiated by IP(3) binding to the IBC (IP(3)-binding core; residues 224-604) and proceeds via re-arrangement of an interface between the IBC and SD (suppressor domain; residues 1-223). Thimerosal (100 μM) stimulated IP(3) binding to the isolated NT (N-terminal; residues 1-604) of IP(3)R1 and IP(3)R2, but not to that of IP(3)R3. Binding of a competitive antagonist (heparin) or partial agonist (dimeric-IP(3)) to NT1 was unaffected by thiomersal, suggesting that the effect of thimerosal is specifically related to IP(3)R activation. IP(3) binding to NT1 in which all cysteine residues were replaced by alanine was insensitive to thimerosal, so too were NT1 in which cysteine residues were replaced in either the SD or IBC. This demonstrates that thimerosal interacts directly with cysteine in both the SD and IBC. Chimaeric proteins in which the SD of the IP(3)R was replaced by the structurally related A domain of a ryanodine receptor were functional, but thimerosal inhibited both IP(3) binding to the chimaeric NT and IP(3)-evoked Ca(2+) release from the chimaeric IP(3)R. This is the first systematic analysis of the effects of a thiol reagent on each IP(3)R subtype. We conclude that thimerosal selectively sensitizes IP(3)R1 and IP(3)R2 to IP(3) by modifying cysteine residues within both the SD and IBC and thereby stabilizing an active conformation of the receptor.

  5. Subtype-selective regulation of IP3 receptors by thimerosal via cysteine residues within the IP3-binding core and suppressor domain

    Science.gov (United States)

    Khan, Samir A.; Rossi, Ana M.; Riley, Andrew M.; Potter, Barry V. L.; Taylor, Colin W.

    2013-01-01

    IP3R (IP3 [inositol 1,4,5-trisphosphate] receptors) and ryanodine receptors are the most widely expressed intracellular Ca2+ channels and both are regulated by thiol reagents. In DT40 cells stably expressing single subtypes of mammalian IP3R, low concentrations of thimerosal (also known as thiomersal), which oxidizes thiols to form a thiomercurylethyl complex, increased the sensitivity of IP3-evoked Ca2+ release via IP3R1 and IP3R2, but inhibited IP3R3. Activation of IP3R is initiated by IP3 binding to the IBC (IP3-binding core; residues 224–604) and proceeds via re-arrangement of an interface between the IBC and SD (suppressor domain; residues 1–223). Thimerosal (100 μM) stimulated IP3 binding to the isolated NT (N-terminal; residues 1–604) of IP3R1 and IP3R2, but not to that of IP3R3. Binding of a competitive antagonist (heparin) or partial agonist (dimeric-IP3) to NT1 was unaffected by thiomersal, suggesting that the effect of thimerosal is specifically related to IP3R activation. IP3 binding to NT1 in which all cysteine residues were replaced by alanine was insensitive to thimerosal, so too were NT1 in which cysteine residues were replaced in either the SD or IBC. This demonstrates that thimerosal interacts directly with cysteine in both the SD and IBC. Chimaeric proteins in which the SD of the IP3R was replaced by the structurally related A domain of a ryanodine receptor were functional, but thimerosal inhibited both IP3 binding to the chimaeric NT and IP3-evoked Ca2+ release from the chimaeric IP3R. This is the first systematic analysis of the effects of a thiol reagent on each IP3R subtype. We conclude that thimerosal selectively sensitizes IP3R1 and IP3R2 to IP3 by modifying cysteine residues within both the SD and IBC and thereby stabilizing an active conformation of the receptor. PMID:23282150

  6. Limitations and possibilities of low cell number ChIP-seq

    Directory of Open Access Journals (Sweden)

    Gilfillan Gregor D

    2012-11-01

    Full Text Available Abstract Background Chromatin immunoprecipitation coupled with high-throughput DNA sequencing (ChIP-seq offers high resolution, genome-wide analysis of DNA-protein interactions. However, current standard methods require abundant starting material in the range of 1–20 million cells per immunoprecipitation, and remain a bottleneck to the acquisition of biologically relevant epigenetic data. Using a ChIP-seq protocol optimised for low cell numbers (down to 100,000 cells / IP, we examined the performance of the ChIP-seq technique on a series of decreasing cell numbers. Results We present an enhanced native ChIP-seq method tailored to low cell numbers that represents a 200-fold reduction in input requirements over existing protocols. The protocol was tested over a range of starting cell numbers covering three orders of magnitude, enabling determination of the lower limit of the technique. At low input cell numbers, increased levels of unmapped and duplicate reads reduce the number of unique reads generated, and can drive up sequencing costs and affect sensitivity if ChIP is attempted from too few cells. Conclusions The optimised method presented here considerably reduces the input requirements for performing native ChIP-seq. It extends the applicability of the technique to isolated primary cells and rare cell populations (e.g. biobank samples, stem cells, and in many cases will alleviate the need for cell culture and any associated alteration of epigenetic marks. However, this study highlights a challenge inherent to ChIP-seq from low cell numbers: as cell input numbers fall, levels of unmapped sequence reads and PCR-generated duplicate reads rise. We discuss a number of solutions to overcome the effects of reducing cell number that may aid further improvements to ChIP performance.

  7. IPS observation system for the Miyun 50 m radio telescope and its commissioning observation

    International Nuclear Information System (INIS)

    Zhu Xinying; Zhang Xizhen; Zhang Hongbo; Kong Deqing; Qu Huipeng

    2012-01-01

    Ground-based observation of Interplanetary Scintillation (IPS) is an important approach for monitoring solar wind. A ground-based IPS observation system has been newly implemented on a 50 m radio telescope at Miyun station, managed by the National Astronomical Observatories, Chinese Academy of Sciences. This observation system has been constructed for the purpose of observing solar wind speed and the associated scintillation index by using the normalized cross-spectrum of a simultaneous dual-frequency IPS measurement. The system consists of a universal dual-frequency front-end and a dual-channel multi-function back-end specially designed for IPS. After careful calibration and testing, IPS observations on source 3C 273B and 3C 279 have been successfully carried out. The preliminary observation results show that this newly-developed observation system is capable of performing IPS observation. The system's sensitivity for IPS observation can reach over 0.3 Jy in terms of an IPS polarization correlator with 4 MHz bandwidth and 2 s integration time. (research papers)

  8. Irradiation testing of miniature fuel plates for the RERTR program

    Energy Technology Data Exchange (ETDEWEB)

    Senn, R L; Martin, M M [Oak Ridge National Laboratory, Oak Ridge, TN 37830 (United States)

    1983-08-01

    An irradiation test facility, which provides a test bed for irradiating a variety of miniature fuel plates miniplates) for the Reduced Enrichment Research and Test Reactors (RERTR) program, has been placed into operation. The objective of these tests is to screen various candidate fuel materials as to their suitability for replacing the highly enriched uranium fuel materials currently used by the world's test and research reactors with a lower enrichment fuel material, without significantly degrading reactor operating characteristics and power levels. The use of low uranium enrichment of about 20% {sup 235}U in place of highly enriched fuel for these reactors would reduce the potential for {sup 235}U diversion. Fuel materials currently being evaluated in this first phase of these screening tests include aluminum-base dispersion-type fuel plates with fuel cores of 1) high uranium content U{sup 3}){sup 8}-Al being developed by ORNL, 2) high uranium content UAI{sub x}-Al being developed by EG and G Idaho, Inc., and 3) very high uranium content U{sub 3}Si-Al- being developed by ANL. The miniplates are 115-mm long by 50-mm wide with overall plate thicknesses of 1.27 or 1.52 mm. The fuel core dimensions vary according to overall plate thicknesses with a minimal clad thickness requirement of 0.20 mm. Sixty such miniplates (thirty of each thickness) can be irradiated in one test facility. The irradiation test facility, designated as HFED-1 is operating in core position E-7 in the Oak Ridge Research Reactor (ORR), a 30-MW water-moderated reactor. The peak neutron flux measured for this experiment is 1.96 x 10{sup 18} neutrons m{sub -2} s{sub -1}. The various types of miniplates will achieve burnups of up to approximately 2.2x10{sup 27} fissions/m{sup 3} of fuel, which will require approximately eight full power months of irradiation. During reactor shutdown periods, the experiment is removed from the reactor, moved to a special poolside station, disassembled, and inspected

  9. Meso-scale modeling of irradiated concrete in test reactor

    International Nuclear Information System (INIS)

    Giorla, A.; Vaitová, M.; Le Pape, Y.; Štemberk, P.

    2015-01-01

    Highlights: • A meso-scale finite element model for irradiated concrete is developed. • Neutron radiation-induced volumetric expansion is a predominant degradation mode. • Confrontation with expansion and damage obtained from experiments is successful. • Effects of paste shrinkage, creep and ductility are discussed. - Abstract: A numerical model accounting for the effects of neutron irradiation on concrete at the mesoscale is detailed in this paper. Irradiation experiments in test reactor (Elleuch et al., 1972), i.e., in accelerated conditions, are simulated. Concrete is considered as a two-phase material made of elastic inclusions (aggregate) subjected to thermal and irradiation-induced swelling and embedded in a cementitious matrix subjected to shrinkage and thermal expansion. The role of the hardened cement paste in the post-peak regime (brittle-ductile transition with decreasing loading rate), and creep effects are investigated. Radiation-induced volumetric expansion (RIVE) of the aggregate cause the development and propagation of damage around the aggregate which further develops in bridging cracks across the hardened cement paste between the individual aggregate particles. The development of damage is aggravated when shrinkage occurs simultaneously with RIVE during the irradiation experiment. The post-irradiation expansion derived from the simulation is well correlated with the experimental data and, the obtained damage levels are fully consistent with previous estimations based on a micromechanical interpretation of the experimental post-irradiation elastic properties (Le Pape et al., 2015). The proposed modeling opens new perspectives for the interpretation of test reactor experiments in regards to the actual operation of light water reactors.

  10. Meso-scale modeling of irradiated concrete in test reactor

    Energy Technology Data Exchange (ETDEWEB)

    Giorla, A. [Oak Ridge National Laboratory, One Bethel Valley Road, Oak Ridge, TN 37831 (United States); Vaitová, M. [Czech Technical University, Thakurova 7, 166 29 Praha 6 (Czech Republic); Le Pape, Y., E-mail: lepapeym@ornl.gov [Oak Ridge National Laboratory, One Bethel Valley Road, Oak Ridge, TN 37831 (United States); Štemberk, P. [Czech Technical University, Thakurova 7, 166 29 Praha 6 (Czech Republic)

    2015-12-15

    Highlights: • A meso-scale finite element model for irradiated concrete is developed. • Neutron radiation-induced volumetric expansion is a predominant degradation mode. • Confrontation with expansion and damage obtained from experiments is successful. • Effects of paste shrinkage, creep and ductility are discussed. - Abstract: A numerical model accounting for the effects of neutron irradiation on concrete at the mesoscale is detailed in this paper. Irradiation experiments in test reactor (Elleuch et al., 1972), i.e., in accelerated conditions, are simulated. Concrete is considered as a two-phase material made of elastic inclusions (aggregate) subjected to thermal and irradiation-induced swelling and embedded in a cementitious matrix subjected to shrinkage and thermal expansion. The role of the hardened cement paste in the post-peak regime (brittle-ductile transition with decreasing loading rate), and creep effects are investigated. Radiation-induced volumetric expansion (RIVE) of the aggregate cause the development and propagation of damage around the aggregate which further develops in bridging cracks across the hardened cement paste between the individual aggregate particles. The development of damage is aggravated when shrinkage occurs simultaneously with RIVE during the irradiation experiment. The post-irradiation expansion derived from the simulation is well correlated with the experimental data and, the obtained damage levels are fully consistent with previous estimations based on a micromechanical interpretation of the experimental post-irradiation elastic properties (Le Pape et al., 2015). The proposed modeling opens new perspectives for the interpretation of test reactor experiments in regards to the actual operation of light water reactors.

  11. Applying a gaming approach to IP strategy.

    Science.gov (United States)

    Gasnier, Arnaud; Vandamme, Luc

    2010-02-01

    Adopting an appropriate IP strategy is an important but complex area, particularly in the pharmaceutical and biotechnology sectors, in which aspects such as regulatory submissions, high competitive activity, and public health and safety information requirements limit the amount of information that can be protected effectively through secrecy. As a result, and considering the existing time limits for patent protection, decisions on how to approach IP in these sectors must be made with knowledge of the options and consequences of IP positioning. Because of the specialized nature of IP, it is necessary to impart knowledge regarding the options and impact of IP to decision-makers, whether at the level of inventors, marketers or strategic business managers. This feature review provides some insight on IP strategy, with a focus on the use of a new 'gaming' approach for transferring the skills and understanding needed to make informed IP-related decisions; the game Patentopolis is discussed as an example of such an approach. Patentopolis involves interactive activities with IP-related business decisions, including the exploitation and enforcement of IP rights, and can be used to gain knowledge on the impact of adopting different IP strategies.

  12. Vaccines and IP Rights: A Multifaceted Relationship.

    Science.gov (United States)

    Durell, Karen

    2016-01-01

    Just as there are many forms of vaccines and components to vaccines-particular compositions, delivery systems, components, and distribution networks-there are a variety of intellectual property (IP) protections applicable for vaccines. IP rights such as patent, copyright, trademarks, plant breeders' rights, and trade secrets may all be applicable to vaccines. Thus, discussion of IP rights and vaccines should not begin and end with the application of one IP right to a vaccine. The discussion should engage considerations of multiple IP rights applicable to a vaccine and how these can be utilized in an integrated manner in a strategy aimed at supporting the development and distribution of the vaccine. Such an approach to IP rights to vaccines allows for the integrated rights to be considered in light of the justifications for protecting vaccines with IP rights, as well as the issues relating to specific IP rights for vaccines, such as compulsory license regimes, available humanitarian purpose IP credits, etc. To view vaccines as the subject of multiple IP protections involves a refocusing, but the outcome can provide significant benefits for vaccine development and distribution.

  13. Investigation of neutron fluence using fluence monitors for irradiation test at WWR-K

    International Nuclear Information System (INIS)

    Romanova, N.K.; Takemoto, N.

    2013-01-01

    Irradiation test of a Si ingot is planned using WWR-K in Institute of Nuclear Physics Republic of Kazakhstan (INP RK) to develop an irradiation technology for Si semiconductor production by Neutron Transmutation Doping (NTD) method in the framework of an international cooperation between INP RK and Japan Atomic Energy Agency (JAEA), Japan. It is possible to irradiate the Si ingot of 6 inch in diameter at the K-23 irradiation channel in the WWR-K. The preliminary irradiation test using 4 Al ingots was performed to evaluate the actual neutronic irradiation field at the K-23 channel in the WWR-K. Each Al ingot has the same dimension as the Si ingot, and 15 fluence monitors are equipped in it. Iron wire and aluminum-cobalt wire are inserted into them, and it is possible to evaluate both fast and thermal neutron fluxes by measurement of these radiation activities after irradiation. This report described the results of the preliminary irradiation test and the neutronic calculations by Monte Carlo method in order to evaluate the neutronic irradiation field in the irradiation position for the silicon ingot at the channel in the WWR-K. (authors)

  14. Irradiation test HT-31: high-temperature irradiation behavior of LASL-made extruded fuel rods and LASL-made coated particles

    International Nuclear Information System (INIS)

    Wagner, P.; Reiswig, R.D.; Hollabaugh, C.M.; White, R.W.; Davidson, K.V.; Schell, D.H.

    1977-04-01

    Three LASL-made extruded graphite and coated particle fuel rods have been irradiated in the Oak Ridge National Laboratory High Fluence Isotope Reactor test HT-31. Test conditions were about 9 x 10 21 nvt(E > .18 MeV) at 1250 0 C. The graphite matrix showed little or no effect of the irradiation. LASL-made ZrC containing coated particles with ZrC coats and ZrC-doped pyrolytic carbon coats showed no observable effects of the irradiation

  15. Development of small scale mechanical testing techniques on ion beam irradiated 304 SS

    International Nuclear Information System (INIS)

    Reichardt, A.; Abad, M.D.; Hosemann, P.; Lupinacci, A.; Kacher, J.; Minor, A.; Jiao, Z; Chou, P.

    2015-01-01

    Austenitic stainless steels are widely used for structural components in light water reactors, however uncertainty in their susceptibility to irradiation assisted stress corrosion cracking (IASCC) has made long term performance predictions difficult. In addition, the testing of reactor irradiated materials has proven challenging due to the long irradiation times required, limited sample availability, and unwanted activation. To address these problems, we apply recently developed techniques in nano-indentation and micro-compression testing to small volume samples of 10 dpa proton-beam irradiated 304 stainless steel. Cross sectional nano-indentation was performed on both proton beam irradiated and non-irradiated samples at temperatures ranging from 22 to 300 C. degrees to determine the effects of irradiation and operating temperature on hardening. Micro-compression tests using 2 μm x 2 μm x 5 μm focused-ion beam milled pillars were then performed in situ in an electron microscope to allow for a more accurate look at stress-strain behavior along with real-time observations of localized mechanical deformation. Large sudden slip events and significant increase in yield strength are observed in irradiated micro-compression samples at room temperature. Elevated temperature nano-indentation results reveal the possibility of thermally-activated changes in deformation mechanism for irradiated specimens. Since the deformation mechanism information provided by micro-compression testing can provide valuable information about IASCC susceptibility, future work will involve ex situ micro-compression tests at reactor operating temperature

  16. Identification of gamma irradiated pulse seed (Lens sp.) based on germination test

    International Nuclear Information System (INIS)

    Chaudhuri, Sadhan K.

    2001-01-01

    The germination test of pulse seed provided a reliable method for the identification of lentil seeds that had been subjected to irradiation. Root and shoot lengths were found more sensitive to the gamma irradiation than the germination percentages. The critical dose that prevented the root elongation varied from 0.1 kGy to 0.5 kGy. Germination percentage was reduced drastically above 0.2 kGy. Above 1.0 kGy dose, the lentil seeds did not germinate. The sensitivity of lentil seeds to gamma irradiation was inversely proportional to moisture content of the seeds. In addition, storage period up to 12 months had little effect on irradiation the induced reduction of root and shoot lengths. Thus, this test can determine the difference between irradiated and non-irradiated lentil seeds even 12 months after gamma irradiation. (author)

  17. Cost of transporting irradiated fuels and maintenance costs of a chemical treatment plant for irradiated fuels; Cout de transport des combustibles irradies et cout d'entretien d'une usine de traitement chimique des combustibles irradies

    Energy Technology Data Exchange (ETDEWEB)

    Sousselier, Y [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1964-07-01

    other plants, an attempt has been made to express the maintenance costs as a percentage of the investments corresponding to each of the sections considered. The unequal aspect of maintenance in a plant of this type is demonstrated, this being due particularly to the inaccessibility of most of the equipment during operation. Finally some conclusions are drawn on what the maintenance costs could be and the means of reducing them in future plants. (author) [French] Le cout du cycle des combustibles a fait l'objet de nombreuses etudes mais beaucoup d'entre elles sont basees sur des etudes a priori et sont donc plus ou moins sujettes a caution. C'est ainsi que dans la partie ayant trait au traitement des combustibles irradies, des elements importants du cout n'ont que rarement ete precises a la suite d'experiences pratiques: le cout du transport des combustibles eux-memes et le cout d'entretien de l'usine. Les etudes relatives au cout du transport sont generalement basees sur des calculs faits a partir de donnees un peu arbitraires. Les etudes qui ont ete faites en France pour le transport d'uranium irradie entre les reacteurs EdF de Chinon et l'usine de retraitement de La Hague et l'uranium irradie des reacteurs de recherches jusqu'aux usines de retraitement etrangeres sont exposees et montrent qu'il a ete possible d'arriver a des types de chateaux de transport et des modalites d'expedition qui permettent de diminuer les couts dans des proportions tres importantes. Ceci a pu etre obtenu soit en combinant les transports par rail et par route soit par l'augmentation des capacites unitaires des chateaux de transport: on cite le cas d'un chateau de transport pour element des piles piscines qui est capable de transporter un coeur complet d'une pile a la fois entrainant une reduction substantielle du cout. Les etudes concernant les couts d'entretien d'usines de retraitement sont encore plus rares, or, dans les usines a entretien direct, ces couts sont une fraction non negligeable

  18. 3D detectors at ITC-irst: first irradiation studies

    International Nuclear Information System (INIS)

    Ronchin, S.; Boscardin, M.; Bosisio, L.; Cindro, V.; Dalla Betta, G.-F.; Piemonte, C.; Pozza, A.; Zoboli, A.; Zorzi, N.

    2007-01-01

    In the past two years, we have developed 3D detector technologies at ITC-irst (Trento, Italy). We have proposed a new 3D architecture, having columnar electrodes of one doping type only, allowing for a simplified fabrication process. In this paper, we report on preliminary results from the electrical characterization of devices irradiated with neutrons, showing that low depletion voltage values can be achieved even after very large fluences

  19. ORR irradiation experiment OF-1: accelerated testing of HTGR fuel

    International Nuclear Information System (INIS)

    Tiegs, T.N.; Long, E.L. Jr.; Kania, M.J.; Thoms, K.R.; Allen, E.J.

    1977-08-01

    The OF-1 capsule, the first in a series of High-Temperature Gas-Cooled Reactor fuel irradiations in the Oak Ridge Research Reactor, was irradiated for more than 9300 hr at full reactor power (30 MW). Peak fluences of 1.08 x 10 22 neutrons/cm 2 (> 0.18 MeV) were achieved. General Atomic Company's magazine P13Q occupied the upper two-thirds of the test space and the ORNL magazine OF-1 the lower one-third. The ORNL portion tested various HTGR recycle particles and fuel bonding matrices at accelerated flux levels under reference HTGR irradiation conditions of temperature, temperature gradient, and fast fluence exposure

  20. A multicentre evaluation of the accuracy and performance of IP-10 for the diagnosis of infection with M. tuberculosis.

    Science.gov (United States)

    Ruhwald, Morten; Dominguez, Jose; Latorre, Irene; Losi, Monica; Richeldi, Luca; Pasticci, Maria Bruna; Mazzolla, Rosanna; Goletti, Delia; Butera, Ornella; Bruchfeld, Judith; Gaines, Hans; Gerogianni, Irini; Tuuminen, Tamara; Ferrara, Giovanni; Eugen-Olsen, Jesper; Ravn, Pernille

    2011-05-01

    IP-10 has potential as a diagnostic marker for infection with Mycobacterium tuberculosis, with comparable accuracy to QuantiFERON-TB Gold In-Tube test (QFT-IT). The aims were to assess the sensitivity and specificity of IP-10, and to evaluate the impact of co-morbidity on IP-10 and QFT-IT. 168 cases with active TB, 101 healthy controls and 175 non-TB patients were included. IP-10 and IFN-γ were measured in plasma of QFT-IT stimulated whole blood and analyzed using previously determined algorithms. A subgroup of 48 patients and 70 healthy controls was tested in parallel with T-SPOT.TB IP-10 and QFT-IT had comparable accuracy. Sensitivity was 81% and 84% with a specificity of 97% and 100%, respectively. Combining IP-10 and QFT-IT improved sensitivity to 87% (p IP-10. Among non-TB patients IP-10 had a higher rate of positive responders (35% vs 27%, p IP-10 responses to mitogen stimulation were reduced in patients with TB and non-TB infection. This study confirms and validates previous findings and adds substance to IP-10 as a novel diagnostic marker for infection with M. tuberculosis. IP-10 appeared less influenced by infections other than TB; further studies are needed to test the clinical impact of these findings. Copyright © 2011 Elsevier Ltd. All rights reserved.

  1. Insulation interlaminar shear strength testing with compression and irradiation

    International Nuclear Information System (INIS)

    McManamy, T.J.; Brasier, J.E.; Snook, P.

    1989-01-01

    The Compact Ignition Tokamak (CIT) project identified the need for research and development for the insulation to be used in the toroidal field coils. The requirements included tolerance to a combination of high compression and shear and a high radiation dose. Samples of laminate-type sheet material were obtained from commercial vendors. The materials included various combinations of epoxy, polyimide, E-glass, S-glass, and T-glass. The T-glass was in the form of a three-dimensional weave. The first tests were with 50 x 25 x 1 mm samples. These materials were loaded in compression and then to failure in shear. At 345-MPa compression, the interlaminar shear strength was generally in the range of 110 to 140 MPa for the different materials. A smaller sample configuration was developed for irradiation testing. The data before irradiation were similar to those for the larger samples but approximately 10% lower. Limited fatigue testing was also performed by cycling the shear load. No reduction in shear strength was found after 50,000 cycles at 90% of the failure stress. Because of space limitations, only three materials were chosen for irradiation: two polyimide systems and one epoxy system. All used boron-free glass. The small shear/compression samples and some flexure specimens were irradiated to 4 x 10 9 and 2 x 10 10 rad in the Advanced Technology Reactor at Idaho National Engineering Laboratory. A lead shield was used to ensure that the majority of the dose was from neutrons. The shear strength with compression before and after irradiation at the lower dose was determined. Flexure strength and the results from irradiation at the higher dose level will be available in the near future. 7 refs., 7 figs., 2 tabs

  2. 26 CFR 1.582-1 - Bad debts, losses, and gains with respect to securities held by financial institutions.

    Science.gov (United States)

    2010-04-01

    ... securities held by financial institutions. 1.582-1 Section 1.582-1 Internal Revenue INTERNAL REVENUE SERVICE... § 1.582-1 Bad debts, losses, and gains with respect to securities held by financial institutions. (a... financial institutions. For taxable years beginning after July 11, 1969, the sale or exchange of a security...

  3. Electric conductivity for laboratory and field monitoring of induced partial saturation (IPS) in sands

    Science.gov (United States)

    Kazemiroodsari, Hadi

    Liquefaction is loss of shear strength in fully saturated loose sands caused by build-up of excess pore water pressure, during moderate to large earthquakes, leading to catastrophic failures of structures. Currently used liquefaction mitigation measures are often costly and cannot be applied at sites with existing structures. An innovative, practical, and cost effective liquefaction mitigation technique titled "Induced Partial Saturation" (IPS) was developed by researchers at Northeastern University. The IPS technique is based on injection of sodium percarbonate solution into fully saturated liquefaction susceptible sand. Sodium percarbonate dissolves in water and breaks down into sodium and carbonate ions and hydrogen peroxide which generates oxygen gas bubbles. Oxygen gas bubbles become trapped in sand pores and therefore decrease the degree of saturation of the sand, increase the compressibility of the soil, thus reduce its potential for liquefaction. The implementation of IPS required the development and validation of a monitoring and evaluation technique that would help ensure that the sands are indeed partially saturated. This dissertation focuses on this aspect of the IPS research. The monitoring system developed was based on using electric conductivity fundamentals and probes to detect the transport of chemical solution, calculate degree of saturation of sand, and determine the final zone of partial saturation created by IPS. To understand the fundamentals of electric conductivity, laboratory bench-top tests were conducted using electric conductivity probes and small specimens of Ottawa sand. Bench-top tests were used to study rate of generation of gas bubbles due to reaction of sodium percarbonate solution in sand, and to confirm a theory based on which degree of saturation were calculated. In addition to bench-top tests, electric conductivity probes were used in a relatively large sand specimen prepared in a specially manufactured glass tank. IPS was

  4. Irradiation test plan of oxidation-resistant graphite in WWR-K Research Reactor

    International Nuclear Information System (INIS)

    Sumita, Junya; Shibata, Taiju; Sakaba, Nariaki; Osaki, Hirotaka; Kato, Hideki; Fujitsuka, Kunihiro; Muto, Takenori; Gizatulin, Shamil; Shaimerdenov, Asset; Dyussambayev, Daulet; Chakrov, Petr

    2014-01-01

    Graphite materials are used for the in-core components of High Temperature Gas-cooled Reactor (HTGR) which is a graphite-moderated and helium gas-cooled reactor. In the case of air ingress accident in HTGR, SiO_2 protective layer is formed on the surface of SiC layer in TRISO CFP and oxidation of SiC does not proceed and fission products are retained inside the fuel particle. A new safety concept for the HTGR, called Naturally Safe HTGR, has been recently proposed. To enhance the safety of Naturally Safe HTGR ultimately, it is expected that oxidation-resistant graphite is used for graphite components to prevent the TRISO CFPs and fuel compacts from failure. SiC coating is one of candidate methods for oxidation-resistant graphite. JAEA and four graphite companies launched R&Ds to develop the oxidation-resistant graphite and the International Science and Technology Center (ISTC) partner project with JAEA and INP was launched to investigate the irradiation effects on the oxidation-resistant graphite. To determine grades of the oxidation-resistant graphite which will be adopted as irradiation test, a preliminary oxidation test was carried out. This paper described the results of the preliminary oxidation test, the plan of out-of-pile test, irradiation test and post-irradiation test (PIE) of the oxidation-resistant graphite. The results of the preliminary oxidation test showed that the integrity of the oxidation resistant graphite was confirmed and that all of grades used in the preliminary test can be adopted as the irradiation test. Target irradiation temperature was determined to be 1473 (K) and neutron fluence was determined to be from 0.54 × 10"2"5through 1.4 × 10"2"5 (/m"2, E>0.18MeV). Weight change, oxidation rate, activation energy, surface condition, etc. will be evaluated in out-of-pile test and weight change, irradiation effect on oxidation rate and activation energy, surface condition, etc. will be evaluated in PIE. (author)

  5. Food safety aspect : Toxicity test of gold fish pepes sterilized by gamma irradiation in vitro

    International Nuclear Information System (INIS)

    Zubaidah Irawati; Kallista Rachmavika Putri; Fransiska Rungkat Zakaria

    2011-01-01

    Ionizing radiation is a physical preservation technique for foods using ionizing energy without impairing the products either natural characteristics or nutritive contents. Formation of free radicals and radiolytic products in irradiated foods may produce toxic substances, mutagen or carcinogenic that can affect the consumer health. Toxicity test as a part of food safety assays on gold fish (Cyprinus carpio ) pepes in a package and irradiated at the dose of 45 kGy under cryogenic condition was conducted through lymphocyte proliferation because lymphocyte cell is responsible for specific immune response and sensitive to unbalance condition between oxidant and anti oxidant in human body. Malonaldehyde content in the irradiated fish was also measured bearing in mind that malonaldehyde content could be used as indicator in the presence of free radicals and as oxidative damage indicator within the matrix of biological material. Dilution steps was done in all samples both in control and irradiated. Irradiation was conducted at three different times i.e., sample irradiated on 11 November 2006 (A), 14 June 2007(B), 5 April 2008 (C) and in 2008 (code: “no label”) (D), respectively. Proliferation of lymphocyte cell was assayed based on Stimulation Index value (SI), and free radical content of all samples was calculated based on malonaldehyde content (pmol/ml). The measurement of SI in sample without dilution showed that the highest value was found in sample B (1.356), but the lowest value was obtained in control (1.161); at one time dilution the highest value was obtained in sample D (1.344), the lowest was found in sample B (1.084) compared to control (1.259). At twice time dilution, the highest value was found in control (1.293), but the lowest was in sample D (0.984). The results of malonaldehyde content (pmol/ml) showed that sample without dilution has the highest quantity was found in sample A (0.1182 pmol/ml), but the lowest was in sample C (0.1178 pmol/ml) for

  6. Extending Tactical Fleet Communications Through VoIP

    Science.gov (United States)

    2014-09-01

    corporate world , the military is leveraging VoIP communication solutions as well. Shore commands like Tactical Training Group Pacific use VoIP for...VoIP fuzzing (e.g., Asteroid , PROTOS, Sip-Proxy)  VoIP signaling manipulation (e.g., IAXAuthJack, IAXHangup, SIP-Kill)  VoIP media...as well, but instead of just matching the information to rules, it compares synchronization information between the protocols to determine if the

  7. Hardware IP security and trust

    CERN Document Server

    Bhunia, Swarup; Tehranipoor, Mark

    2017-01-01

    This book provides an overview of current Intellectual Property (IP) based System-on-Chip (SoC) design methodology and highlights how security of IP can be compromised at various stages in the overall SoC design-fabrication-deployment cycle. Readers will gain a comprehensive understanding of the security vulnerabilities of different types of IPs. This book would enable readers to overcome these vulnerabilities through an efficient combination of proactive countermeasures and design-for-security solutions, as well as a wide variety of IP security and trust assessment and validation techniques. This book serves as a single-source of reference for system designers and practitioners for designing secure, reliable and trustworthy SoCs.

  8. Adjusting the IP $\\beta$ Functions in RHIC

    CERN Document Server

    Wittmer, W; Pilat, F; Ptitsyn, V; Van Zeijts, J

    2004-01-01

    The beta functions at the IP can be adjusted without perturbation of other optics functions via several approaches. In this paper we describe a scheme based on a vector knob, which assigns fixed values to the different tuning quadrupoles and scales them by a common multiplier. The values for the knob vector were calculated for a lattice without any errors using MADX. Previous studies for the LHC [1] have shown that this approach can meet the design goals. A specific feature of the RHIC lattice is the nested power supply system. To cope with the resulting problems a detailed response matrix analysis has been carried out and different sets of knobs were calculated and compared. The knobs were tested at RHIC during the 2004 run and preliminary results are discussed. Simultaneously a new approach to measure the beam sizes of both colliding beams at the IP, based on the tunability provided by the knobs, was developed and tested.

  9. Irradiation experiments and materials testing capabilities in High Flux Reactor in Petten

    International Nuclear Information System (INIS)

    Luzginova, N.; Blagoeva, D.; Hegeman, H.; Van der Laan, J.

    2011-01-01

    The text of publication follows: The High Flux Reactor (HFR) in Petten is a powerful multi-purpose research and materials testing reactor operating for about 280 Full Power Days per year. In combination with hot cells facilities, HFR provides irradiation and post-irradiation examination services requested by nuclear energy research and development programs, as well as by industry and research organizations. Using a variety of the custom developed irradiation devices and a large experience in executing irradiation experiments, the HFR is suitable for fuel, materials and components testing for different reactor types. Irradiation experiments carried out at the HFR are mainly focused on the understanding of the irradiation effects on materials; and providing databases for irradiation behavior of materials to feed into safety cases. The irradiation experiments and materials testing at the HFR include the following issues. First, materials irradiation to support the nuclear plant life extensions, for instance, characterization of the reactor pressure vessel stainless steel claddings to insure structural integrity of the vessel, as well as irradiation of the weld material coupons to neutron fluence levels that are representative for Light Water Reactors (LWR) internals applications. Secondly, development and qualification of the structural materials for next generation nuclear fission reactors as well as thermo-nuclear fusion machines. The main areas of interest are in both conventional stainless steel and advanced reduced activation steels and special alloys such as Ni-base alloys. For instance safety-relevant aspects of High Temperature Reactors (HTR) such as the integrity of fuel and structural materials with increasing neutron fluence at typical HTR operating conditions has been recently assessed. Thirdly, support of the fuel safety through several fuel irradiation experiments including testing of pre-irradiated LWR fuel rods containing UO 2 or MOX fuel. Fourthly

  10. Presence in the IP multimedia subsystem

    NARCIS (Netherlands)

    Lin, L.; Liotta, A.

    2007-01-01

    With an ever increasing penetration of Internet Protocol (IP) technologies, the wireless industry is evolving the mobile core network towards all-IP network. The IP Multimedia Subsystem (IMS) is a standardised Next Generation Network (NGN) architectural framework defined by the 3rd Generation

  11. A comparison of interferon-γ and IP-10 for the diagnosis of tuberculosis

    DEFF Research Database (Denmark)

    Holm, Line Lindebo; Rose, Michala Vaaben; Kimaro, Godfather

    2014-01-01

    OBJECTIVE: Interferon-γ and IP-10 release assays are diagnostic tests for tuberculosis infection. We have compared the accuracy of IP-10 and QuantiFERON-TB Gold In-tube [QFT-IT] in Tanzanian children suspected of having active tuberculosis (TB). METHODS: Hospitalized Tanzanian children...

  12. Performance of VoIP on HSDPA

    DEFF Research Database (Denmark)

    Wang, Bang; Pedersen, Klaus I.; Kolding, Troels E.

    2005-01-01

    This paper provides packet scheduler design and performance simulations for running VoIP services over high-speed downlink packet access (HSDPA) in WCDMA. The main challenge of supporting VoIP service on HSDPA is the tight delay requirement combined with the small VoIP packet size. A packet...... scheduler design incorporating VoIP packet aggregation and user multiplexing is proposed and the VoIP capacity is studied for a macro-cellular environment. Results are obtained for different delay budgets and packet scheduling settings, using either blind round robin or a slightly modified version...... of proportional fair scheduling. For proportional fair scheduling with code-multiplexing of 4-users, the downlink VoIP cell capacity on HSDPA is found to be in the range 72-104 users depending on whether the delay budget for the Node-B scheduling and user reception equals 80 ms or 150 ms, respectively....

  13. Thermohydraulic design of saturated temperature capsule for IASCC irradiation test

    International Nuclear Information System (INIS)

    Ide, Hiroshi; Matsui, Yoshinori; Itabashi, Yukio

    2002-10-01

    An advanced water chemistry controlled irradiation research device is being developed in JAERI, to perform irradiation tests for irradiation assisted stress corrosion cracking (IASCC) research concerned with aging of LWR. This device enables the irradiation tests under the water chemistry condition and the temperature, which simulate the conditions for BWR core internals. The advanced water chemistry controlled irradiation research device is composed of saturated temperature capsule inserted into the JMTR core and the water chemistry control unit installed in the reactor building. Regarding the saturated temperature capsule, the Thermohydraulic design of capsule structure was done, aimed at controlling the specimen's temperature, feeding water velocity on specimen's surface to the environment of BWR nearer. As the result of adopting the new capsule structure based on the design study, it was found out that feeding water velocity at the surface of specimen's is increased to about 10 times as much as before, and nuclear heat generated in the capsule components can be removed safely even in the abnormal event such as the case of loss of feeding water. (author)

  14. Thermohydraulic design of saturated temperature capsule for IASCC irradiation test

    Energy Technology Data Exchange (ETDEWEB)

    Ide, Hiroshi; Matsui, Yoshinori; Itabashi, Yukio [Japan Atomic Energy Research Inst., Oarai, Ibaraki (Japan). Oarai Research Establishment] [and others

    2002-10-01

    An advanced water chemistry controlled irradiation research device is being developed in JAERI, to perform irradiation tests for irradiation assisted stress corrosion cracking (IASCC) research concerned with aging of LWR. This device enables the irradiation tests under the water chemistry condition and the temperature, which simulate the conditions for BWR core internals. The advanced water chemistry controlled irradiation research device is composed of saturated temperature capsule inserted into the JMTR core and the water chemistry control unit installed in the reactor building. Regarding the saturated temperature capsule, the Thermohydraulic design of capsule structure was done, aimed at controlling the specimen's temperature, feeding water velocity on specimen's surface to the environment of BWR nearer. As the result of adopting the new capsule structure based on the design study, it was found out that feeding water velocity at the surface of specimen's is increased to about 10 times as much as before, and nuclear heat generated in the capsule components can be removed safely even in the abnormal event such as the case of loss of feeding water. (author)

  15. Project accent: graphite irradiated creep in a materials test reactor

    International Nuclear Information System (INIS)

    Brooking, M.

    2014-01-01

    Atkins manages a pioneering programme of irradiation experiments for EDF Energy. One of these projects is Project ACCENT, designed to obtain evidence of a beneficial physical property of the graphite, which may extend the life of the Advanced Gas-cooled Reactors (AGRs). The project team combines the in-house experience of EDF Energy with two supplier organisations (providing the material test reactors and testing facilities) and supporting consultancies (Atkins and an independent technical expert). This paper describes: - Brief summary of the Project; - Discussion of the challenges faced by the Project; and - Conclusion elaborating on the aims of the Project. These challenging experiments use bespoke technology and both un-irradiated (virgin) and irradiated AGR graphite. The results will help to better understand graphite irradiation-induced creep (or stress modified dimensional change) properties and therefore more accurately determine lifetime and safe operating envelopes of the AGRs. The first round of irradiation has been completed, with a second round about to commence. This is a key step to realising the full lifetime ambition for AGRs, demonstrating the relaxation of stresses within the graphite bricks. (authors)

  16. Summary of ALSEP Test Loop Solvent Irradiation Testing

    Energy Technology Data Exchange (ETDEWEB)

    Peterman, Dean Richard [Idaho National Lab. (INL), Idaho Falls, ID (United States); Olson, Lonnie Gene [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2016-08-01

    Separating the minor actinide elements (americium and curium) from the fission product lanthanides is an important step in closing the nuclear fuel cycle. Isolating the minor actinides will allow transmuting them to short lived or stable isotopes in fast reactors, thereby reducing the long-term hazard associated with these elements. The Actinide Lanthanide Separation Process (ALSEP) is being developed by the DOE-NE Material Recovery and Waste Form Development Campaign to accomplish this separation with a single process. To develop a fundamental understanding of the solvent degradation mechanisms for the ALSEP Process, testing was performed in the INL Radiolysis/Hydrolysis Test Loop for the extraction section of the ALSEP flowsheet. This work culminated in the completion of the level two milestone (M2FT-16IN030102021) "Complete ALSEP test loop solvent irradiation test.” This report summarizes the testing performed and the impact of radiation on the ALSEP Process performance as a function of dose.

  17. Effects of age on muscarinic agonist-induced contraction an IP accumulation in airway smooth muscle

    International Nuclear Information System (INIS)

    Wills-Karp, M.

    1991-01-01

    The effects of age on carbachol-stimulated force development and [ 3 H]inositol phosphate production was studied in tracheal rings from guinea pigs aged 1 month and 25 months of age. The pD 2 for the contractile response to carbachol was significantly reduced in tracheal tissues from old animals as compared to that of the young tissues, respectively. In contrast, inositol phosphate formation was not altered with increasing age when stimulated by carbachol or NaF, a direct activator of G proteins. Carbachol-induced inositol phosphate accumulation was inhibited by treatment with 1μg/ml pertussis toxin, suggesting that IP1 accumulation is coupled to a pertussis-toxin-sensitive protein. The pD 2 values for contraction were significantly different from the pD 2 values for IP1 accumulation, in both young and old tissues, respectively. These data suggest that IP1 accumulation is not responsible for the decreased contractile ability in tracheal smooth muscle during aging

  18. Effects of age on muscarinic agonist-induced contraction an IP accumulation in airway smooth muscle

    Energy Technology Data Exchange (ETDEWEB)

    Wills-Karp, M. (Johns Hopkins Univ., Baltimore, MD (United States))

    1991-01-01

    The effects of age on carbachol-stimulated force development and ({sup 3}H)inositol phosphate production was studied in tracheal rings from guinea pigs aged 1 month and 25 months of age. The pD{sub 2} for the contractile response to carbachol was significantly reduced in tracheal tissues from old animals as compared to that of the young tissues, respectively. In contrast, inositol phosphate formation was not altered with increasing age when stimulated by carbachol or NaF, a direct activator of G proteins. Carbachol-induced inositol phosphate accumulation was inhibited by treatment with 1{mu}g/ml pertussis toxin, suggesting that IP1 accumulation is coupled to a pertussis-toxin-sensitive protein. The pD{sub 2} values for contraction were significantly different from the pD{sub 2} values for IP1 accumulation, in both young and old tissues, respectively. These data suggest that IP1 accumulation is not responsible for the decreased contractile ability in tracheal smooth muscle during aging.

  19. Fabrication, inspection, and test plan for the Advanced Test Reactor (ATR) Mixed-Oxide (MOX) fuel irradiation project

    International Nuclear Information System (INIS)

    Wachs, G.W.

    1997-11-01

    The Department of Energy (DOE) Fissile Materials Disposition Materials Disposition Program (FMDP) has announced that reactor irradiation of MOX fuel is one of the preferred alternatives for disposal of surplus weapons-usable plutonium (Pu). MOX fuel has been utilized domestically in test reactors and on an experimental basis in a number of Commercial Light Water Reactors (CLWRs). Most of this experience has been with Pu derived from spent low enriched uranium (LEU) fuel, known as reactor grade (RG) Pu. The MOX fuel test will be irradiated in the ATR to provide preliminary data to demonstrate that the unique properties of surplus weapons-derived or weapons-grade (WG) plutonium (Pu) do not compromise the applicability of this MOX experience base. In addition, the test will contribute experience with irradiation of gallium-containing fuel to the data base required for resolution of generic CLWR fuel design issues (ORNL/MD/LTR-76). This Fabrication, Inspection, and Test Plan (FITP) is a level 2 document as defined in the FMDP LWR MOX Fuel Irradiation Test Project Plan (ORNL/MD/LTR-78)

  20. Irradiated diets and its effect on testes and adrenal gland of rats

    International Nuclear Information System (INIS)

    Kushwaha, A.K.S.; Hasan, S.S.

    1988-01-01

    The present investigation was undertaken to study the feeding effects of irradiated normal diet (consisting of equal parts of gram and wheat) and irradiated low protein diet (consisting one part of normal diet and three parts of wheat) on male rats for various periods starting from weaning time. Rats maintained on irradiated low protein diets showed decrease in the activity of androgen sensitive enzymes i.e., alkaline and acid phosphatase while an increase in the cholesterol content of the testes compared with irradiated normal controls. Diminution in androgen sensitive enzymes and accumulation of cholesterol in the rat testes suggest non-conversion of cholesterol into steriod hormones after feeding of irradiated low protein. Besides, rats fed on irradiated low protein diet showed increased cellular activity in the adrenal cortex and medulla as compared to rats fed on the irradiated normal diet. (author). 12 refs., 4 tabs

  1. Remote-handling demonstration tests for the Fusion Materials Irradiation Test (FMIT) Facility

    International Nuclear Information System (INIS)

    Shen, E.J.; Hussey, M.W.; Kelly, V.P.; Yount, J.A.

    1982-01-01

    The mission of the Fusion Materials Irradiation Test (FMIT) Facility is to create a fusion-like environment for fusion materials development. Crucial to the success of FMIT is the development and testing of remote handling systems required to handle materials specimens and maintenance of the facility. The use of full scale mock-ups for demonstration tests provides the means for proving these systems

  2. The Spacelab IPS Star Simulator

    Science.gov (United States)

    Wessling, Francis C., III

    The cost of doing business in space is very high. If errors occur while in orbit the costs grow and desired scientific data may be corrupted or even lost. The Spacelab Instrument Pointing System (IPS) Star Simulator is a unique test bed that allows star trackers to interface with simulated stars in a laboratory before going into orbit. This hardware-in-the loop testing of equipment on earth increases the probability of success while in space. The IPS Star Simulator provides three fields of view 2.55 x 2.55 degrees each for input into star trackers. The fields of view are produced on three separate monitors. Each monitor has 4096 x 4096 addressable points and can display 50 stars (pixels) maximum at a given time. The pixel refresh rate is 1000 Hz. The spectral output is approximately 550 nm. The available relative visual magnitude range is 2 to 8 visual magnitudes. The star size is less than 100 arc seconds. The minimum star movement is less than 5 arc seconds and the relative position accuracy is approximately 40 arc seconds. The purpose of this paper is to describe the LPS Star Simulator design and to provide an operational scenario so others may gain from the approach and possible use of the system.

  3. D2-H2 equilibration over γ-irradiated zeolites

    International Nuclear Information System (INIS)

    Novakova, J.; Wichterlova, B.

    1987-01-01

    D 2 -H 2 equilibration was studied at 77 and 298 K over HY, AlHY, HZSM-5 and Alsub(x)Osub(y)HZSM-5 zeolites which had been γ-irradiated at 77 and/or 298 K. The exchange rate was found to be higher at the lower temperature regardless of the temperature of irradiation. Moreover, at 77 K the exchange rates were similar and more stable over the individual zeolites than at 298 K, thus indicating a common reaction path at 77 K. The exchange rate at 298 K depended on the zeolite type: it was more stable and higher over HZSM-5 than over HY, and extra-lattice Al increased both these properties on HY as well as on HZSM-5. The reaction mechanism is discussed in connection with the nature of defects generated by γ-irradiation. (author)

  4. Design and fabrication of water control unit for IASCC irradiation test

    International Nuclear Information System (INIS)

    Mori, Yuichiro; Takeuchi, Yutaka; Matsunami, Kiyotaka; Kosaki, Kazuhiko; Suzuki, Tomio; Hayashi, Motomitsu; Ide, Kiyoshi

    2004-01-01

    In relation to the aging of LWR, the Irradiation Assisted Stress Corrosion Cracking (IASCC) has been regarded as a significant and urgent issue for the reliability of in-core components of LWR, therefore the irradiation research project which was planned by Nuclear and Industrial Safety Agency is now being done under the cooperation of Industry-Government-Academia such as Japan Nuclear Energy Safety Organization, Institute of Research and Innovation (IRI), Central Research Institute of Electric Power Industry, Japan Atomic Energy Research Institute (JAERI), power companies, makers of LWR, and universities. Then at Japan Material Testing Reactor (JMTR) of JAERI, the irradiation test of the material for BWR is being carried out. This paper describes the introduction about the Water Control Unit (WCU) for IASCC irradiation test. The WCU was designed and installed into JMTR by Kawasaki Heavy Industries, LTD, based on the order from JAERI, IRI, and so on. (author)

  5. Comparison of properties and microstructures of Trefimetaux CuNiBe and Hycon 3HP TM before and after neutron irradiation. (ITER R and D Task no. T213)

    International Nuclear Information System (INIS)

    Edwards, D.J.; Eldrup, M.; Toft, P.; Singh, B.N.

    2000-07-01

    The precipitation strengthened CuNiBe alloys are among the three candidate copper alloys that are being evaluated for application in the first wall, divertor, and limiter components of ITER. Generally, CuNiBe alloys have higher strength but poorer conductivity compared to CuCrZr and Cu-A1 2 O 3 alloys. Brush-Wellman Inc. has developed an improved version of their Hycon CuNiBe alloy that has higher conductivity while maintaining a reasonable level of strength. In the present work we have investigated the physical and mechanical properties of the Hycon 3HP TM alloy both before and after neutron irradiation and have compared its microstructure and properties with the European CuNiBe candidate alloy manufactured by Trefimetaux. Tensile specimens of both alloys were irradiated in the DR-3 reactor at Risoe to displacement dose levels of up to 0.3 dpa at 100, 250 and 350 d eg C . Both alloys were tensile tested in vacuum in the unirradiated and irradiated conditions at 100, 250 and 350 d eg C and the microstructures of the alloys were investigated using transmission electron microscopy. Electrical resistivity measurements were made on tensile specimens be-fore and after irradiation; all measurements were made at 23 d eg C . Results of these investigations are presented and discussed in terms of the sensitivity of these alloys to test temperature, which becomes increasingly problematic when the irradiation and test temperature reaches 250 d eg C and above. (au)

  6. Microstructure and elemental distribution of americium containing MOX fuel under the short term irradiation tests

    International Nuclear Information System (INIS)

    Tanaka, Kosuke; Hirosawa, Takashi; Obayashi, Hiroshi; Koyama, Shin Ichi; Yoshimochi, Hiroshi; Tanaka, Kenya

    2008-01-01

    In order to investigate the effect of americium addition to MOX fuels on the irradiation behavior, the 'Am-1' program is being conducted in JAEA. The Am-1 program consists of two short term irradiation tests of 10-minute and 24 hour irradiations and a steady-state irradiation test. The short-term irradiation tests were successfully completed and the post irradiation examinations (PIEs) are in progress. The PIEs for Am-containing MOX fuels focused on the microstructural evolution and redistribution behavior of Am at the initial stage of irradiation and the results to date are reported

  7. The characteristics of Fugi IP Cassette Type PII and application for radiation oncology quality assurance tests and portal imaging

    International Nuclear Information System (INIS)

    Soh, H.S.; Ung, N.M.; Ng, K.H.

    2008-01-01

    Full text: The advancement of digital imaging has prompted more medical institutions to go filmless. The computed radiography (CR) system is becoming an important tool not only in diagnostic imaging, but also in radiation oncology. A new CR system that was specially designed for the use in radiation oncology. Fuji IP cassette type PII has been introduced to the market in the middle of year 2006. This project aimed to study some basic physical characteristics of this new type of cassette and explore its application for performing quality assurance (QA) tests and portal imaging in radiotherapy. All the images were read by FCR 5000 Plus reader. The image was found to reach its saturation value of 1023 (due to the image was stored in 10 bits data) by depending on the sensitivity value being adjusted. The uniformity test gave the result of 0.12%. The cassette was used to perform the QA tests which were previously performed using film. All the results met the specification as stated in AAPM Task Group 40. The comparison for the portal images of Portal Vision contrast-detail phantom showed that the spatial resolution of the images obtained by CR system (Fujifilm Co.. Ltd.. Tokyo. Japan) were better than the EPID (Varian Medical Systems. Inc.. Palo Alto. USA) and film system (Eastman Kodak Co.. New York. USA). The IP cassette type PII was found to be suitable as an alternative QA test tool and portal imaging in radiotherapy.

  8. Measuring the impostor phenomenon: a comparison of Clance's IP Scale and Harvey's I-P Scale.

    Science.gov (United States)

    Holmes, S W; Kertay, L; Adamson, L B; Holland, C L; Clance, P R

    1993-02-01

    Many of the discrepancies reported to date in empirical investigations of the impostor phenomenon (IP) may be due in part to (a) the use of different methods for identifying individuals suffering from this syndrome (impostors), (b) the common use of a median split procedure to classify subjects and (c) the fact that subjects in many studies were drawn from impostor-prone samples. In this study, we compared the scores of independently identified impostors and nonimpostors on two instruments designed to measure the IP: Harvey's I-P Scale and Clance's IP Scale. The results suggest that Clance's scale may be the more sensitive and reliable instrument. Cutoff score suggestions for both instruments are offered.

  9. 5 CFR 582.402 - Maximum garnishment limitations.

    Science.gov (United States)

    2010-01-01

    ... earnings that may be garnished for a Federal, State or local tax obligation or in compliance with an order... alimony, including any amounts withheld to offset administrative costs as provided for in § 582.305(k... of an employee-obligor's aggregate disposable earnings for any workweek in compliance with legal...

  10. Postirradiation examination results for the Irradiation Effects Test 2

    International Nuclear Information System (INIS)

    Ploger, S.A.; Kerwin, D.K.; Croucher, D.W.

    1978-01-01

    This report presents the postirradiation examination results of Test IE-2 in the Irradiation Effects Test Series conducted under the Thermal Fuels Behavior Program. The objectives of this test were to evaluate the influence of previous cladding irradiation and fuel-cladding diametral gap on fuel rod behavior during a power ramp and during film boiling operation. Test IE-2, conducted in the Power Burst Facility at the Idaho National Engineering Laboratory, employed two 0.97-m-long pressurized water reactor type fuel rods fabricated from previously irradiated zircaloy-4 cladding and two similar rods fabricated from unirradiated cladding. The four rods were subjected to a preconditioning period, followed by a power ramp to an average peak rod power of 68 kW/m and steady state operation for one hour at an individual rod coolant mass flux of 4880 kg/s . m 2 . After a flow reduction to 2550 kg/s . m 2 , film boiling occurred on three rods. An additional flow reduction to 2245 kg/s . m 2 produced film boiling on the remaining fuel rod. Maximum time in film boiling was 90 s. None of the four fuel rods failed during the test. Damage caused by film boiling, as characterized by oxidation, oxide spalling, and collapse at fuel pellet interfaces, was found on all four rods. Film boiling regions on these rods showed evidence of fuel melting, fuel centerline void formation, and internal cladding oxidation resulting from fuel-cladding reaction. Effects of fuel-cladding diametral gap and cladding irradiation are summarized. Measured temperatures and metallographically estimated temperatures are compared at several axial fuel rod locations

  11. A comparison of the microstructure and properties of the IPS Empress 2 and the IPS Empress glass-ceramics.

    Science.gov (United States)

    Höland, W; Schweiger, M; Frank, M; Rheinberger, V

    2000-01-01

    The aim of this report is to analyze the microstructures of glass-ceramics of the IPS Empress 2 and IPS Empress systems by scanning electron microscopy. The main properties of the glass-ceramics were determined and compared to each other. The flexural strength of the pressed glass-ceramic (core material) was improved by a factor of more than three for IPS Empress 2 (lithium disilicate glass-ceramic) in comparison with IPS Empress (leucite glass-ceramic). For the fracture toughness, the K(IC) value was measured as 3.3 +/- 0.3 MPa. m(0.5) for IPS Empress 2 and 1.3 +/- 0.1 MPa. m(0.5) for IPS Empress. Abrasion behavior, chemical durability, and optical properties such as translucency of all glass-ceramics fulfill the dental standards. The authors concluded that IPS Empress 2 can be used to fabricate 3-unit bridges up to the second premolar. Copyright 2000 John Wiley & Sons, Inc.

  12. An investigation of high-temperature irradiation test program of new ceramic materials

    International Nuclear Information System (INIS)

    Ishino, Shiori; Terai, Takayuki; Oku, Tatsuo

    1999-08-01

    The Japan Atomic Energy Research Institute entrusted the Atomic Energy Society of Japan with an investigation into the trend of irradiation processing/damage research on new ceramic materials. The present report describes the result of the investigation, which was aimed at effective execution of irradiation programs using the High Temperature Engineering Test Reactor (HTTR) by examining preferential research subjects and their concrete research methods. Objects of the investigation were currently on-going preliminary tests of functional materials (high-temperature oxide superconductor and high-temperature semiconductor) and structural materials (carbon/carbon and SiC/SiC composite materials), together with newly proposed subjects of, e.g., radiation effects on ceramics-coated materials and super-plastic ceramic materials as well as microscopic computer simulation of deformation and fracture of ceramics. These works have revealed 1) the background of each research subject, 2) its objective and significance from viewpoints of science and engineering, 3) research methodology in stages from preliminary tests to real HTTR irradiation, and 4) concrete HTTR-irradiation methods which include main specifications of test specimens, irradiation facilities and post-irradiation examination facilities and apparatuses. The present efforts have constructed the important fundamentals in the new ceramic materials field for further planning and execution of the innovative basic research on high-temperature engineering. (author)

  13. Design and fuel fabrication processes for the AC-3 mixed-carbide irradiation test

    International Nuclear Information System (INIS)

    Latimer, T.W.; Chidester, K.M.; Stratton, R.W.; Ledergerber, G.; Ingold, F.

    1992-01-01

    The AC-3 test was a cooperative U.S./Swiss irradiation test of 91 wire-wrapped helium-bonded U-20% Pu carbide fuel pins irradiated to 8.3 at % peak burnup in the Fast Flux Test Facility. The test consisted of 25 pins that contained spherepac fuel fabricated by the Paul Scherrer Institute (PSI) and 66 pins that contained pelletized fuel fabricated by the Los Alamos National Laboratory. Design of AC-3 by LANL and PSI was begun in 1981, the fuel pins were fabricated from 1983 to 1985, and the test was irradiated from 1986 to 1988. The principal objective of the AC-3 test was to compare the irradiation performance of mixed-carbide fuel pins that contained either pelletized or sphere-pac fuel at prototypic fluence and burnup levels for a fast breeder reactor

  14. Effects of gamma-irradiation of plastics on migration of constituents into test foods

    International Nuclear Information System (INIS)

    Figge, K.; Freytag, W.

    1977-01-01

    Test films prepared from polyethylene (LD- and HD-PE), polypropylene (PP), polystyrene (St- and HI-PS) and polyvinylchloride (rigid PVC) compositions under addition of 2,6-di-tert-butyl-4-methyl[ 14 C]-phenol(I), 3-(3,5-di-tert-butyl -4-hydroxyphenyl)- stearyl-propionate[3- 14 C] (II), n-butyl-stearate[1- 14 C] (III) di-n-octyl[1- 14 C]-tin-2 -ethyl-hexyl-di-thioglycolate inclusive of the corresponding mono-n-octyl[1- 14 C]-tin compound (IV-Oc), di-n-octyl-tin-2-ethylhexyl -di-thioglycolate[2- 14 C] inclusive of the corresponding 2-ethylhexyl-tri -thioglycolate[2- 14 C] (IV-S) or of stearyl alcohol [1- 14 C] (V) respectively, were sterilized in a 60 Co irradiation unit with a radiation dosage of 2,5 Mrad. Then, the irradiated films as well as non-treated reference films were kept in one-sided contact with the test foodstuffs 'dist. Water' and HB 307 (test fat) for 10 days at 40 0 C. Under these conditions the additives I and II migrated from the PP, HD-PE and LD-PE test films into the test fat HB 307 in amounts of 10 to 50%. Migration into distilled water was only 0.05 to 4.6%. The migration of the additives I and II from the irradiated polyolefin test films into the test fat HB 307 was by 8 to 38% lower than that from the corresponding non-irradiated films. In contrast to this, both additives migrated distinctly more strongly from the irradiated polyolefin test films into distilled water, i.e. 1.9 to 8.7 times stronger than from the non-irradiated films. The migration of the additives I to V from the HI-PS St-PS and rigid PVC test films into the two test foodstuffs was very low, in most cases below 0.1%. Generally lower amounts of additive migrated from the irradiated films than from the non-irradiated samples. (orig.) [de

  15. ChIP-PIT: Enhancing the Analysis of ChIP-Seq Data Using Convex-Relaxed Pair-Wise Interaction Tensor Decomposition.

    Science.gov (United States)

    Zhu, Lin; Guo, Wei-Li; Deng, Su-Ping; Huang, De-Shuang

    2016-01-01

    In recent years, thanks to the efforts of individual scientists and research consortiums, a huge amount of chromatin immunoprecipitation followed by high-throughput sequencing (ChIP-seq) experimental data have been accumulated. Instead of investigating them independently, several recent studies have convincingly demonstrated that a wealth of scientific insights can be gained by integrative analysis of these ChIP-seq data. However, when used for the purpose of integrative analysis, a serious drawback of current ChIP-seq technique is that it is still expensive and time-consuming to generate ChIP-seq datasets of high standard. Most researchers are therefore unable to obtain complete ChIP-seq data for several TFs in a wide variety of cell lines, which considerably limits the understanding of transcriptional regulation pattern. In this paper, we propose a novel method called ChIP-PIT to overcome the aforementioned limitation. In ChIP-PIT, ChIP-seq data corresponding to a diverse collection of cell types, TFs and genes are fused together using the three-mode pair-wise interaction tensor (PIT) model, and the prediction of unperformed ChIP-seq experimental results is formulated as a tensor completion problem. Computationally, we propose efficient first-order method based on extensions of coordinate descent method to learn the optimal solution of ChIP-PIT, which makes it particularly suitable for the analysis of massive scale ChIP-seq data. Experimental evaluation the ENCODE data illustrate the usefulness of the proposed model.

  16. Mutagenicity tests on irradiated food

    International Nuclear Information System (INIS)

    Johnston-Arthur, T.

    1979-01-01

    The mutagenicity of ''standard'' food pellets from three different suppliers was tested after radappertization and after sterilization with steam, respectively. The histidine-deficient mutants G-46 and TA-1530 of salmonella typhimurium were used as indicators in a hostmediated assay. The mutant TA-1530 showed a highly sighificant increase of the back-mutation frequency after feeding with pellets irradiated with 3 Mrad gamma radiation. There were, however, large quantitative differences between the products of different suppliers. (G.G.)

  17. Sirt1 suppresses RNA synthesis after UV irradiation in combined xeroderma pigmentosum group D/Cockayne syndrome (XP-D/CS) cells.

    Science.gov (United States)

    Vélez-Cruz, Renier; Zadorin, Anton S; Coin, Frédéric; Egly, Jean-Marc

    2013-01-15

    Specific mutations in the XPD subunit of transcription factor IIH result in combined xeroderma pigmentosum (XP)/Cockayne syndrome (CS), a severe DNA repair disorder characterized at the cellular level by a transcriptional arrest following UV irradiation. This transcriptional arrest has always been thought to be the result of faulty transcription-coupled repair. In the present study, we showed that, following UV irradiation, XP-D/CS cells displayed a gross transcriptional dysregulation compared with "pure" XP-D cells or WT cells. Furthermore, global RNA-sequencing analysis showed that XP-D/CS cells repressed the majority of genes after UV, whereas pure XP-D cells did not. By using housekeeping genes as a model, we demonstrated that XP-D/CS cells were unable to reassemble these gene promoters and thus to restart transcription after UV irradiation. Furthermore, we found that the repression of these promoters in XP-D/CS cells was not a simple consequence of deficient repair but rather an active heterochromatinization process mediated by the histone deacetylase Sirt1. Indeed, RNA-sequencing analysis showed that inhibition of and/or silencing of Sirt1 changed the chromatin environment at these promoters and restored the transcription of a large portion of the repressed genes in XP-D/CS cells after UV irradiation. Our work demonstrates that a significant part of the transcriptional arrest displayed by XP-D/CS cells arises as a result of an active repression process and not simply as a result of a DNA repair deficiency. This dysregulation of Sirt1 function that results in transcriptional repression may be the cause of various severe clinical features in patients with XP-D/CS that cannot be explained by a DNA repair defect.

  18. Design and fabrication of irradiation testing capsule for research reactor materials

    International Nuclear Information System (INIS)

    Yang, Seong Woo; Kim, Bong Goo; Park, Seung Jae; Cho, Man Soon; Choo, Kee Nam; Oh, Jong Myeong; Choi, Myeong Hwan; Lee, Byung Chul; Kang, Suk Hoon; Kim, Dae Jong; Chun, Young Bum; Kim, Tae Kyu

    2012-01-01

    Recently, the demand of research reactors is increasing because there are many ageing research reactors in the world. Also, the production of radioisotope related with the medical purpose is very important. Korea Atomic Energy Research Institute (KAERI) is designing and licensing for Jordan Research and Training Reactor (JRTR) and new type research reactor for export which will be constructed in Amman, Jordan and Busan, Korea, respectively. Thus, It is expected that more research reactors will be designed and constructed by KAERI. To design the research reactor, the irradiation performance and behavior of core structure material are necessary. However, the irradiation behavior of these materials is not yet investigated. Therefore, the irradiation performance must be verified by irradiation test. 11M 20K and 11M 21K irradiation capsules were designed and fabricated to conduct the irradiation test for some candidate core materials, Zircaloy 4, beryllium, and graphite, at HANARO. In this paper, the design and fabrication features of 11M 20K and 11M 21K were discussed

  19. Design and fabrication of irradiation testing capsule for research reactor materials

    Energy Technology Data Exchange (ETDEWEB)

    Yang, Seong Woo; Kim, Bong Goo; Park, Seung Jae; Cho, Man Soon; Choo, Kee Nam; Oh, Jong Myeong; Choi, Myeong Hwan; Lee, Byung Chul; Kang, Suk Hoon; Kim, Dae Jong; Chun, Young Bum; Kim, Tae Kyu [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2012-10-15

    Recently, the demand of research reactors is increasing because there are many ageing research reactors in the world. Also, the production of radioisotope related with the medical purpose is very important. Korea Atomic Energy Research Institute (KAERI) is designing and licensing for Jordan Research and Training Reactor (JRTR) and new type research reactor for export which will be constructed in Amman, Jordan and Busan, Korea, respectively. Thus, It is expected that more research reactors will be designed and constructed by KAERI. To design the research reactor, the irradiation performance and behavior of core structure material are necessary. However, the irradiation behavior of these materials is not yet investigated. Therefore, the irradiation performance must be verified by irradiation test. 11M 20K and 11M 21K irradiation capsules were designed and fabricated to conduct the irradiation test for some candidate core materials, Zircaloy 4, beryllium, and graphite, at HANARO. In this paper, the design and fabrication features of 11M 20K and 11M 21K were discussed.

  20. Extraction Of Electronic Evidence From VoIP: Identification & Analysis Of Digital Speech

    Directory of Open Access Journals (Sweden)

    David Irwin

    2012-09-01

    Full Text Available The Voice over Internet Protocol (VoIP is increasing in popularity as a cost effective and efficient means of making telephone calls via the Internet. However, VoIP may also be an attractive method of communication to criminals as their true identity may be hidden and voice and video communications are encrypted as they are deployed across the Internet. This produces in a new set of challenges for forensic analysts compared with traditional wire-tapping of the Public Switched Telephone Network (PSTN infrastructure, which is not applicable to VoIP. Therefore, other methods of recovering electronic evidence from VoIP are required.  This research investigates the analysis and recovery of digitised human, which persists in computer memory after a VoIP call.This paper proposes a proof of concept how remnants of digitised human speech from a VoIP call may be identified within a forensic memory capture based on how the human voice is detected via a microphone and encoded to a digital format using the sound card of your personal computer. This digital format is unencrypted whist processed in Random Access Memory (RAM before it is passed to the VoIP application for encryption and  transmission over the Internet. Similarly, an incoming encrypted VoIP call is decrypted by the VoIP application and passes through RAM unencrypted in order to be played via the speaker output.A series of controlled tests were undertaken whereby RAM captures were analysed for remnants of digital speech after a VoIP audio call with known conversation. The identification and analysis of digital speech from RAM attempts to construct an automatic process for the identification and subsequent reconstruction of the audio content of a VoIP call.

  1. An embedded offset and gain instrument for OpAmp IPs

    NARCIS (Netherlands)

    Wan, J.; Kerkhoff, Hans G.

    2014-01-01

    Analog and mixed-signal IPs are increasingly required to use digital fabrication technologies and are deeply embedded into system-on-chips (SoC). These developments append more requirements and challenges on analog testing methodologies. Traditional analog testing methods suffer from less

  2. PIE Report on the KOMO-3 Irradiation Test Fuels

    International Nuclear Information System (INIS)

    Park, Jong Man; Ryu, H. J.; Yang, J. H.

    2009-04-01

    In the KOMO-3, in-reactor irradiation test had been performed for 12 kinds of dispersed U-Mo fuel rods, a multi wire fuel rod and a tube fuel rod. In this report we described the PIE results on the KOMO-3 irradiation test fuels. The interaction layer thickness between fuel particle and matrix could be reduced by using a large size U-Mo fuel particle or introducing Al-Si matrix or adding the third element in the U-Mo particle. Monolithic fuel rod of multi-wire or tube fuel was also effective in reducing the interaction layer thickness

  3. Status of irradiation testing and PIE of MOX (Pu-containing) fuel

    International Nuclear Information System (INIS)

    Dimayuga, F.C.; Zhou, Y.N.; Ryz, M.A.

    1995-01-01

    This paper describes AECL's mixed oxide (MOX) fuel-irradiation and post-irradiation examination (PIE) program. Post-irradiation examination results of two major irradiation experiments involving several (U, Pu)O 2 fuel bundles are highlighted. One experiment involved bundles irradiated to burnups ranging fro 400 to 1200 MWh/kgHe in the Nuclear Power Demonstration (NPD) reactor. The other experiment consisted of several (U, Pu)O 2 bundles irradiated to burnups of up to 500 Mwh/kgHe in the National Research Universal (NRU) reactor. Results of these experiments demonstrate the excellent performance of CANDU MOX fuel. This paper also outlines the status of current MOX fuel irradiation tests, including the irradiation of various (U, Pu)O 2 bundles. The strategic importance of MOX fuel to CANDU fuel-cycle flexibility is discussed. (author)

  4. Voice over IP in Wireless Heterogeneous Networks

    DEFF Research Database (Denmark)

    Fathi, Hanane; Chakraborty, Shyam; Prasad, Ramjee

    with the deployment of wireless heterogeneous systems, both speech and data traffic are carrried over wireless links by the same IP-based packet-switched infrastructure. However, this combination faces some challenges due to the inherent properties of the wireless network. The requirements for good quality VoIP...... communications are difficult to achieve in a time-varying environment due to channel errors and traffic congestion and across different systems. The provision of VoIP in wireless heterogeneous networks requires a set of time-efficient control mechanisms to support a VoIP session with acceptable quality....... The focus of Voice over IP in Wierless Heterogeneous Networks is on mechanisms that affect the VoIP user satisfaction  while not explicitly involved in the media session. This relates to the extra delays introduced by the security and the signaling protocols used to set up an authorized VoIP session...

  5. miR-582-5p is upregulated in patients with active tuberculosis and inhibits apoptosis of monocytes by targeting FOXO1.

    Directory of Open Access Journals (Sweden)

    Yanhua Liu

    Full Text Available Macrophage apoptosis is a host innate defense mechanism against tuberculosis (TB. In this study, we found that percentage of apoptotic cells in peripheral blood monocytes from patients with active TB was lower than that from healthy controls (p<0.001. To understand whether microRNAs can modulate apoptosis of monocytes, we investigated differentially expressed microRNAs in patients with active TB. miR-582-5p was mainly expressed in monocytes and was upregulated in patients with active TB. The apoptotic percentage of THP-1 cells transfected with miR-582-5p mimics was significantly lower than those transfected with negative control of microRNA mimics (p<0.001, suggesting that miR-582-5p could inhibit apoptosis of monocytes. To our knowledge, the role of miR-582-5p in regulating apoptosis of monocytes has not been reported so far. Systematic bioinformatics analysis indicated that FOXO1 might be a target gene for miR-582-5p and its 3'UTR contains potential binding sites for miR-582-5p. To determine whether miR-582-5p could influence FOXO1 expression, miR-582-5p mimics or negative control of microRNA mimics were transfected into THP-1 cells. RT-PCR and western blot analysis showed that the miR-582-5p could suppress both FOXO1 mRNA and protein expression. Co-transfection of miR-582-5p and FOXO1 3'UTR-luciferase reporter vector into cells demonstrated that significant decrease in luciferase activity was only found in reporter vector that contained a wild type sequence of FOXO1 3'UTR, suggesting that miR-582-5p could directly target FOXO1. In conclusion, miR-582-5p inhibited apoptosis of monocytes by down-regulating FOXO1 expression and might play an important role in regulating anti-M. tuberculosis directed immune responses.

  6. Potassium Channel Interacting Protein 2 (KChIP2) is not a transcriptional regulator of cardiac electrical remodeling

    DEFF Research Database (Denmark)

    Winther, Sine V; Tuomainen, Tomi; Borup, Rehannah

    2016-01-01

    The heart-failure relevant Potassium Channel Interacting Protein 2 (KChIP2) augments CaV1.2 and KV4.3. KChIP3 represses CaV1.2 transcription in cardiomyocytes via interaction with regulatory DNA elements. Hence, we tested nuclear presence of KChIP2 and if KChIP2 translocates into the nucleus...... intracellular Ca(2+) concentration. Neither increasing nor decreasing intracellular Ca(2+) concentrations caused translocation of KChIP2. Microarray analysis did not identify relief of transcriptional repression in murine KChIP2(-/-) heart samples. We conclude that although there is a baseline presence of KCh...

  7. Irradiation Test in HANARO of the Parts of an X-Gen Nuclear Fuel Assembly

    Energy Technology Data Exchange (ETDEWEB)

    Choo, K. N.; Kim, B. G.; Kang, Y. H. (and others)

    2008-08-15

    An instrumented capsule of 07M-13N was designed, fabricated and irradiated for an evaluation of the neutron irradiation properties of the parts of an X-Gen nuclear fuel assembly for PWR requested by KNF. Some specimens requested by Westinghouse Co. and Hanyang university were also inserted. 389 KNF specimens such as bucking and spring test specimens of 1x1 cell spacer grid, tensile, microstructure and tensile of welded parts, irradiation growth, spring test specimens made of HANA tube, Zirlo, Zircaloy-4, Inconel-718 were placed in the capsule. The capsule was composed of 5 stages having many kinds of specimens and an independent electric heater at each stage. During the irradiation test, the temperature of the specimens and the thermal/fast neutron fluences were measured by 14 thermocouples and 7 sets of Ni-Ti-Fe (2 sets contain additional Nb-Ag) neutron fluence monitors installed in the capsule. The capsule was irradiated for 59.19days (4 cycles) in the CT test hole of HANARO of a 30MW thermal output at 300 {approx} 420 .deg. C(for KNF specimens) up to a fast neutron fluence of 1.27x10{sup 21}(n/cm{sup 2}) (E>1MeV). After an irradiation test, the main body of the capsule was cut off at the bottom of the protection tube with a cutting system and it was transported to the IMEF (Irradiated Materials Examination Facility). The irradiated specimens were tested to evaluate the irradiation performance of the parts of an X-Gen fuel assembly in the IMEF hot cell.

  8. Chromatin immunoprecipitation (ChIP) of plant transcription factors followed by sequencing (ChIP-SEQ) or hybridization to whole genome arrays (ChIP-CHIP)

    NARCIS (Netherlands)

    Kaufmann, K.; Muiño, J.M.; Østerås, M.; Farinelli, L.; Krajewski, P.; Angenent, G.C.

    2010-01-01

    Chromatin immunoprecipitation (ChIP) is a powerful technique to study interactions between transcription factors (TFs) and DNA in vivo. For genome-wide de novo discovery of TF-binding sites, the DNA that is obtained in ChIP experiments needs to be processed for sequence identification. The sequences

  9. Experimental data report for Test TS-1 Reactivity Initiated Accident Test in NSRR with pre-irradiated BWR fuel rod

    International Nuclear Information System (INIS)

    Nakamura, Takehiko; Yoshinaga, Makio; Sobajima, Makoto; Fujishiro, Toshio; Horiki, Ohichiro; Yamahara, Takeshi; Ichihashi, Yoshinori; Kikuchi, Teruo

    1992-01-01

    This report presents experimental data for Test TS-1 which was the first in a series of tests, simulating Reactivity Initiated Accident (RIA) conditions using pre-irradiated BWR fuel rods, performed in the Nuclear Safety Research Reactor (NSRR) in October, 1989. Test fuel rod used in the Test TS-1 was a short-sized BWR (7 x 7) type rod which was fabricated from a commercial rod provided from Tsuruga Unit 1 power reactor. The fuel had an initial enrichment of 2.79 % and burnup of 21.3 GWd/t (bundle average). Pulse irradiation was performed at a condition of stagnant water cooling, atmospheric pressure and ambient temperature using a newly developed double container-type capsule. Energy deposition of the rod in this test was evaluated to be about 61 cal/g·fuel (55 cal/g·fuel in peak fuel enthalpy) and no fuel failure was observed. Descriptions on test conditions, test procedures, fuel burnup measurements, transient behavior of the test rod during pulse irradiation and results of post pulse irradiation examinations are contained in this report. (author)

  10. Pre- and post-irradiation performance of FBK 3D silicon pixel detectors for CMS

    International Nuclear Information System (INIS)

    Krzywda, A.; Alagoz, E.; Bubna, M.; Obertino, M.; Solano, A.; Arndt, K.; Uplegger, L.; Betta, G.F. Dalla; Boscardin, M.; Ngadiuba, J.; Rivera, R.; Menasce, D.; Moroni, L.; Terzo, S.; Bortoletto, D.; Prosser, A.; Adreson, J.; Kwan, S.; Osipenkov, I.; Bolla, G.

    2014-01-01

    In preparation for the tenfold luminosity upgrade of the Large Hadron Collider (the HL-LHC) around 2020, three-dimensional (3D) silicon pixel sensors are being developed as a radiation-hard candidate to replace the planar ones currently being used in the CMS pixel detector. This study examines an early batch of FBK sensors (named ATLAS08) of three 3D pixel geometries: 1E, 2E, and 4E, which respectively contain one, two, and four readout electrodes for each pixel, passing completely through the bulk. We present electrical characteristics and beam test performance results for each detector before and after irradiation. The maximum fluence applied is 3.5×10 15 n eq /cm 2

  11. Heat-treated mineral-yeast as a potent post-irradiation radioprotector

    International Nuclear Information System (INIS)

    Anzai, Kazunori; Ueno, Megumi; Nyui, Minako; Ikota, Nobuo; Kagiya, Tsutomu V.

    2008-01-01

    In vivo radioprotection of C3H mice by i.p. administration of Zn-, Mn-, Cu-, or Se-containing heat-treated Saccharomyces serevisiae yeast sample was examined. The 30-day survival of the group treated 30 min before 7.5 Gy whole-body X-irradiation with mineral-containing yeast powders suspended in 0.5% methylcellulose was significantly higher than that of control group. When mineral-yeast was administered immediately after irradiation, the survival rate was even higher and Zn- or Cu-yeast showed the highest rate (more than 90%). Although treatment with simple yeast showed a high survival rate (73%), it was significantly lower than that obtained by the Zn-yeast treatment. The effects of Zn-yeast were studied further. When the interval between irradiation and administration was varied, the protective activity of Zn-yeast decreased gradually by increasing the interval but was still significantly high for the administration at 10 h post-irradiation. The dose reduction factor of Zn-yeast (100 mg/kg, i.p. administration immediately after irradiation) was about 1.2. When the suspension of Zn-yeast was fractionated by centrifugation, the insoluble fraction showed a potent effect, while the soluble fraction had only a moderate effect. In conclusion, mineral-yeast, especially Zn-yeast, provides remarkable post-irradiation protection against lethal whole body X-irradiation. The activity is mainly attributable to the insoluble fraction, whereas some soluble components might contribute to the additional protective activity. (author)

  12. Generation of glucose-responsive functional islets with a three-dimensional structure from mouse fetal pancreatic cells and iPS cells in vitro.

    Directory of Open Access Journals (Sweden)

    Hiroki Saito

    Full Text Available Islets of Langerhans are a pancreatic endocrine compartment consisting of insulin-producing β cells together with several other hormone-producing cells. While some insulin-producing cells or immature pancreatic cells have been generated in vitro from ES and iPS cells, islets with proper functions and a three-dimensional (3D structure have never been successfully produced. To test whether islets can be formed in vitro, we first examined the potential of mouse fetal pancreatic cells. We found that E16.5 pancreatic cells, just before forming islets, were able to develop cell aggregates consisting of β cells surrounded by glucagon-producing α cells, a structure similar to murine adult islets. Moreover, the transplantation of these cells improved blood glucose levels in hyperglycemic mice. These results indicate that functional islets are formed in vitro from fetal pancreatic cells at a specific developmental stage. By adopting these culture conditions to the differentiation of mouse iPS cells, we developed a two-step system to generate islets, i.e. immature pancreatic cells were first produced from iPS cells, and then transferred to culture conditions that allowed the formation of islets from fetal pancreatic cells. The islets exhibited distinct 3D structural features similar to adult pancreatic islets and secreted insulin in response to glucose concentrations. Transplantation of the islets improved blood glucose levels in hyperglycemic mice. In conclusion, the two-step culture system allows the generation of functional islets with a 3D structure from iPS cells.

  13. Analisis Kualitas VoIP pada SCTP Menggunakan ECN dan AQM

    Directory of Open Access Journals (Sweden)

    La Surimi

    2015-07-01

    Abstract VoIP is the real time applications that are highly dependent on the quality of  delay and jitter, which it is difficult to be met by protocol that has reliable data transfer feature and  congestion control such as TCP. On the other hand the use of UDP that has no congestion control make chance of causing congestion in the network is very large. The use of SCTP as an alternative protocol was also not able to accommodate the weaknesses of TCP and UDP. Some research shows that repairs or modifications to the SCTP congestion control mechanism is needed. The Use of ECN and AQM in some studies show that these two mechanisms can reduce delay and jitter. This study tested the quality of VoIP over SCTP with ECN and AVQ, in NS2. Simulations carried out by independent replication technique, and the results showed that ECN and AVQ can increase the value of MOS VoIP calls significantly in non ideal network scenarios. This study also did comparison of SCTP MOS that uses ECN and AVQ with MOS values VoIP using TCP and UDP. The result showed that SCTP with ECN and AVQ outperform TCP but can not surpass UDP yet.   Keywords— VoIP, SCTP, ECN, AQM,AVQ.

  14. Experimental data report for test TS-3 Reactivity Initiated Accident test in the NSRR with pre-irradiated BWR fuel rod

    International Nuclear Information System (INIS)

    Nakamura, Takehiko; Yoshinaga, Makio; Fujishiro, Toshio; Kobayashi, Shinsho; Yamahara, Takeshi; Sukegawa, Tomohide; Kikuchi, Teruo; Sobajima, Makoto.

    1993-09-01

    This report presents experimental data for Test TS-3 which was the third test in a series of Reactivity Initiated Accident (RIA) tests using pre-irradiated BWR fuel rods, performed in the Nuclear Safety Research Reactor (NSRR) in September, 1990. Test fuel rod used in the Test TS-3 was a short-sized BWR (7 x 7) type rod which was re-fabricated from a commercial rod irradiated in the Tsuruga Unit 1 power reactor of Japan Atomic Power Co. The fuel had an initial enrichment of 2.79 % and a burnup of 26 Gwd/tU. A pulse irradiation of the test fuel rod was performed under a cooling condition of stagnant water at atmospheric pressure and at ambient temperature which simulated a BWR's cold start-up RIA event. The energy deposition of the fuel rod in this test was evaluated to be 94 ± 4 cal/g · fuel (88 ± 4 cal/g · fuel in peak fuel enthalpy) and no fuel failure was observed. Descriptions on test conditions, test procedures, transient behavior of the test rod during the pulse irradiation, and results of pre-pulse and post-pulse irradiation examinations are described in this report. (author)

  15. Antigen-Specific IP-10 Release Is a Sensitive Biomarker of Mycobacterium bovis Infection in Cattle.

    Directory of Open Access Journals (Sweden)

    Sven D C Parsons

    Full Text Available The most widely used ante-mortem diagnostic tests for tuberculosis in cattle are the tuberculin skin test and the interferon-gamma (IFN-γ release assay, both of which measure cell-mediated immune responses to Mycobacterium bovis infection. However, limitations in the performance of these tests results in a failure to identify all infected animals. In attempting to increase the range of diagnostic tests for tuberculosis, measurement of the cytokine IP-10 in antigen-stimulated blood has previously been shown to improve the detection of M. tuberculosis and M. bovis infection, in humans and African buffaloes (Syncerus caffer, respectively. In the present study, 60 cattle were identified by the single intradermal comparative tuberculin test as tuberculosis reactors (n = 24 or non-reactors (n = 36 and the release of IFN-γ and IP-10 in antigen-stimulated whole blood from these animals was measured using bovine specific ELISAs. There was a strong correlation between IP-10 and IFN-γ production in these samples. Moreover, measurement of the differential release of IP-10 in response to stimulation with M. bovis purified protein derivative (PPD and M. avium PPD distinguished between reactor and non-reactor cattle with a sensitivity of 100% (95% CI, 86%-100% and a specificity of 97% (95% CI, 85%-100%. These results suggest that IP-10 might prove valuable as a diagnostic biomarker of M. bovis infection in cattle.

  16. Ion irradiation studies on the void swelling behavior of a titanium modified D9 alloy

    Science.gov (United States)

    Balaji, S.; Mohan, Sruthi; Amirthapandian, S.; Chinnathambi, S.; David, C.; Panigrahi, B. K.

    2015-12-01

    The sensitivity of Positron Annihilation Spectroscopy (PAS) for probing vacancy defects and their environment is well known. Its applicability in determination of swelling and the peak swelling temperature was put to test in our earlier work on ion irradiated D9 alloys [1]. Upon comparison with the peak swelling temperature determined by conventional step height measurements it was found that the peak swelling temperature determined using PAS was 50 K higher. It was conjectured that the positrons trapping in the irradiation induced TiC precipitation could have caused the shift. In the present work, D9 alloys have been implanted with 100 appm helium ions and subsequently implanted with 2.5 MeV Ni ions up to peak damage of 100 dpa. The nickel implantations have been carried out through a range of temperatures between 450 °C and 650 °C. The evolution of cavities and TiC precipitates at various temperatures has been followed by TEM and this report provides an experimental verification of the conjecture.

  17. AGR 3/4 Irradiation Test Final As Run Report

    Energy Technology Data Exchange (ETDEWEB)

    Collin, Blaise P. [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2015-06-01

    Several fuel and material irradiation experiments have been planned for the Idaho National Laboratory Advanced Reactor Technologies Technology Development Office Advanced Gas Reactor Fuel Development and Qualification Program (referred to as the INL ART TDO/AGR fuel program hereafter), which supports the development and qualification of tristructural-isotropic (TRISO) coated particle fuel for use in HTGRs. The goals of these experiments are to provide irradiation performance data to support fuel process development, qualify fuel for normal operating conditions, support development and validation of fuel performance and fission product transport models and codes, and provide irradiated fuel and materials for post irradiation examination and safety testing (INL 05/2015). AGR-3/4 combined the third and fourth in this series of planned experiments to test TRISO coated low enriched uranium (LEU) oxycarbide fuel. This combined experiment was intended to support the refinement of fission product transport models and to assess the effects of sweep gas impurities on fuel performance and fission product transport by irradiating designed-to-fail fuel particles and by measuring subsequent fission metal transport in fuel-compact matrix material and fuel-element graphite. The AGR 3/4 fuel test was successful in irradiating the fuel compacts to the burnup and fast fluence target ranges, considering the experiment was terminated short of its initial 400 EFPD target (Collin 2015). Out of the 48 AGR-3/4 compacts, 42 achieved the specified burnup of at least 6% fissions per initial heavy-metal atom (FIMA). Three capsules had a maximum fuel compact average burnup < 10% FIMA, one more than originally specified, and the maximum fuel compact average burnup was <19% FIMA for the remaining capsules, as specified. Fast neutron fluence fell in the expected range of 1.0 to 5.5×1025 n/m2 (E >0.18 MeV) for all compacts. In addition, the AGR-3/4 experiment was globally successful in keeping the

  18. Food irradiation: Activities and potentialities

    Science.gov (United States)

    Doellstaedt, R.; Huebner, G.

    After the acceptance of food irradiation up to an overall average dose of 10 kGy recommended by the Joint FAO/IAEA/WHO Expert Committee on the Wholesomeness of Irradiated Food in October 1980, the G.D.R. started a programme for the development of techniques for food irradiation. A special onion irradiator was designed and built as a pilot plant for studying technological and economic parameters of the irradiation of onions. The new principle of bulk-cargo irradiation allows the integration of this technology into the usual harvest technology for onions on the way from field to storage. Scientific and applied research work has been carried out in the past 3 yr on the irradiation of spices, potatoes, eviscerated chicken, animal feeds, fodder yeast, drugs and vaccines. In connection with the irradiation of eviscerated chicken, fodder yeast and animal feeds the basis of an antisalmonella programme has been discussed. Germ-count-reduced spices were employed for the production of test charges of preserves and tinned products. The results have led to the decision to design and build a new multipurpose irradiator for food irradiation. In order to cover the legal aspects of food irradiation the Ministry of Health issued regulations concerning the recommendation of irradiated food in the G.D.R.

  19. PENGARUH METODE PEMBELAJARAN DAN GAYA BELAJAR SISWA TERHADAP HASIL BELAJAR IPS DI SMP NEGERI DI KOTA YOGYAKARTA

    Directory of Open Access Journals (Sweden)

    Prihma Sinta Utami

    2015-03-01

    ______________________________________________________________ THE EFFECT OF LEARNING METHOD AND LEARNING STYLE ON THE ACHIEVEMENT IN IPS OF THE STUDENTS OF JUNIOR HIGH SCHOOLS IN YOGYAKARTA Abstract This research aims to revealthe effect of: (1 teaching methods on IPS learning outcomes, (2 the influence of learning styles on IPS learning outcomes, (3 the methods and learning styles on IPS learning outcomes. This research was a quasi experiment using the 2x2 factorial design. This research was conducted at SMP Negeri 15 Yogyakarta. The sample was VII B, VII E, VII H, and VII J classes, which was established using the simple random sampling technique. The data collection used a test and questionnaire. The instrument validity was measured by using the product moment formula and its realiability was measured by using Cronbanch’s Alpha. The data normality was tested by using Kolmogorof-Smirnov and the homogeneity test was tested by using Levene Test. The hypothesis of this research was tested by using the two-way Anova technique at the significance level of 0,05. The result of this research shows that: (1 the achievement in IPS of the students taught using the Think Pair Share method is higher than that of those taught using the problem-based learning method; (2 the achievement of the students taught using the Think Pair Share method is higher than that of those taught using the problem-based learning method for group of visual learning style; (3 the achievement of the students taught using the Think Pair Share method is higher than that of those taught using the problem-based learning method for group of auditorial learning style; and (4 there is no interaction between teaching method and learning style in influencing students’ achievement in IPS subject matter. Keywords:methods, learning style, IPS subject outcomes

  20. Periodontal response to all-ceramic crowns (IPS Empress) in general practice.

    Science.gov (United States)

    Al-Wahadni, A M; Mansour, Y; Khader, Y

    2006-02-01

    The purpose of this study was to investigate the periodontal response to the presence of all-ceramic crowns (IPS Empress) in general practice patients. The convenience sample included 82 IPS Empress crowns placed in 64 patients. These crowns had been in place for an average of 16.27 (SD 9.26) months and ranged from 6.2 to 48.87 months at the time of clinical examination. Periodontal health status (as determined by dental plaque, gingival health status, periodontal pockets) was assessed around all crowned teeth and around matched contralateral teeth by one calibrated examiner. Periodontal indices utilized included the Plaque Index (PI), Gingival Index (GI) and pocket depth (PD) with calibrated probes graduated in millimetres. Plaque, gingival and PD values for crowned teeth were compared with those for control teeth using Wilcoxon signed-rank test for each clinical parameters. Chi-square was used to test the significance of the difference in their distribution between crowns and control teeth. Statistically, PI (0.35), GI (0.41) and mean PD scores (1.42) of IPS Empress crowned teeth compared less favourably with scores of the control teeth (0.27, 0.23 and 0.86 respectively). Teeth with IPS Empress crowns had poorer periodontal health and more clinically evident plaque than uncrowned teeth.

  1. Pre-equilibrium Longitudinal Flow in the IP-Glasma Framework for Pb+Pb Collisions at the LHC

    Science.gov (United States)

    McDonald, Scott; Shen, Chun; Fillion-Gourdeau, François; Jeon, Sangyong; Gale, Charles

    2017-08-01

    In this work, we debut a new implementation of IP-Glasma and quantify the pre-equilibrium longitudinal flow in the IP-Glasma framework. The saturation physics based IP-Glasma model naturally provides a non-zero initial longitudinal flow through its pre-equilibrium Yang-Mills evolution. A hybrid IP-Glasma+MUSIC+UrQMD frame-work is employed to test this new implementation against experimental data and to make further predictions about hadronic flow observables in Pb+Pb collisions at 5.02 TeV. Finally, the non-zero pre-equilibrium longitudinal flow of the IP-Glasma model is quantified, and its origin is briefly discussed.

  2. Neutron irradiation characteristic tests of oxygen sensors using zirconia solid electrolyte

    International Nuclear Information System (INIS)

    Hiura, Nobuo; Endou, Yasuichi; Yamaura, Takayuki; Niimi, Motoji; Hoshiya, Taiji; Saito, Junichi; Souzawa, Shizuo; Ooka, Norikazu; Kobiyama, Mamoru.

    1997-03-01

    In the Department of JMTR of Japan Atomic Energy Research Institute (JAERI), the in-situ measuring technique of oxygen potential has been being developed to study the chemical behavior of high burn-up fuel base-irradiated in the Light Water Reactor. In this test for development of the technique, oxygen sensors using zirconia solid electrolyte stabilized by MgO, CaO and Y 2 O 3 , named MSZ, CSZ and YSZ, respectively, were irradiated by neutrons in the Japan Materials Testing Reactor (JMTR) of JAERI and the characteristics of electromotive force of these sensors under and after irradiation were discussed. From the experimental results, the electromotive force of YSZ sample under irradiation decreased with an increase in irradiation fluence within a range of neutron fluence (E>1 MeV) up to 1 x 10 23 m -2 . The electromotive force of MSZ sensor irradiated with neutron fluences (E>1 MeV) up to 9 x 10 21 m -2 was almost equal to the theoretical value of the electromotive force. It was shown that after irradiation, a decrease in the electromotive force of CSZ sensor was smaller than those of MSZ and YSZ sensors, although the electromotive forces of MSZ, CSZ and YSZ sensors were smaller than the theoretical value. (author)

  3. Assessment of cognitive functions after prophylactic and therapeutic whole brain irradiation using neuropsychological testing

    International Nuclear Information System (INIS)

    Penitzka, S.; Wannenmacher, M.; Steinvorth, S.; MIT, Cambridge, MT; Sehlleier, S.; Universitaetsklinikum Wuerzburg; Fuss, M.; Texas Univ., San Antonio, TX; Wenz, F.; Universitaetsklinikum Mannheim

    2002-01-01

    Purpose: Aim of this study was the assessment of neuropsychological changes after whole brain irradiation. Patients and Method: 64 patients were tested before, and 29 after whole brain irradiation, including 28 patients with small cell lung cancer (SCLC) before prophylactic cranial irradiation (PCI) and 36 patients with cerebral metastases before therapeutic cranial irradiation (TCI), as well as 14 patients after PCI and 15 after TCI (Table 1). Intelligence, attention and memory were assessed applying a 90-minute test battery of standardized, neuropsychological tests (Table 3). Results: Patients with SCLC showed test results significantly below average before PCI (n=28, mean IQ=83, SD=17). Neither after PCI, nor after TCI the tested neuropsychological functions decreased significantly (Tables 4, 5). A comparison between SCLC-patients with and without cerebral metastases before whole brain irradiation showed better test-results in patients with cerebral metastases and fewer cycles of preceding chemotherapy (Table 7). Conclusion: Neuropsychological capacity in patients with SCLC was impaired even before PCI. Possible reason is the preceding chemotherapy. Whole brain irradiation did not induce a significant decline of cognitive functions in patients with PCI or TCI. A decline in a longer follow-up nevertheless seems possible. (orig.) [de

  4. Dislocation loops and their depth profiles in He[sup +] and D[sup +] ion irradiated nickel

    Energy Technology Data Exchange (ETDEWEB)

    Niwase, K [Dept. of Physics, Hyogo Univ. of Teacher Education, Yashiro (Japan); Ezawa, T [Dept. of Material Physics, Faculty of Engineering Science, Osaka Univ., Toyonaka (Japan); Tanabe, T [Dept. of Nuclear Engineering, Faculty of Engineering, Osaka Univ., Suita (Japan); Kiritani, M [Dept. of Nuclear Engineering, School of Engineering, Nagoya Univ. (Japan); Fujita, F E [Dept. of Material Physics, Faculty of Engineering Science, Osaka Univ., Toyonaka (Japan)

    1993-07-01

    Effects of implanted deuterium and helium on the formation of dislocation loops in Ni have been systematically investigated in terms of the irradiation temperature and dose by means of transmission electron microscopy. Significant enhancement of loop formation is observed only for He[sup +] irradiation. The number density of loops at 200 C for He[sup +] irradiation is about one order of magnitude higher than that of D[sup +] irradiation and the difference increases at higher temperatures. Significant decrease in the density occurs at about 300 C for D[sup +] irradiation, but it appears at about 600 C for He[sup +] irradiation. Below 200 C, continuous nucleation of loops is observed only for He[sup +] irradiation. The change in the loop depth distribution suggests that the nucleation of loops for He[sup +] irradiation is enhanced by some defects with a low mobility such as small He-vacancy complexes. The significant decrease in the loop density above 600 C is explained by the decrease in the concentration of the small He-vacancy complexes due to their absorption by large cavities or their escape to the specimen surface. (orig.)

  5. Vibration test report on the instrumented capsule for fuel irradiation test

    Energy Technology Data Exchange (ETDEWEB)

    Ryu, Jeong Soo; Yoon, D. B.; Wu, J. S.; Oh, J. M.; Park, S. J.; Cho, M. S.; Kim, B. G.; Kang, Y. W

    2003-01-01

    The fluid-induced vibration level of instrumented capsule, which was manufactured for fuel irradiation test at the reactor core of HANARO, was investigated. For this purpose, the instrumented capsule was loaded at the OR site of the HANARO design verification test facility that could simulate identical flow condition as the HANARO core. Then, vibration signals of the instrumented capsule subjected to various flow conditions were measured by using vibration sensors. In time domain analysis, maximum amplitudes and RMS values of the measured acceleration and displacement signals were obtained. By using frequency domain analysis, frequency components of the fluid-induced vibration were analyzed. In addition, natural frequencies of the instrumented capsule were obtained by performing modal test. The frequency analysis results showed that the natural frequency components near 7.5Hz and 17.5Hz were dominant in the fluid-induced vibration signal. The maximum amplitude of the accelerations was measured as 12.04m/s{sup 2} that is within the allowable vibrational limit(18.99m/s{sup 2})of the reactor structure. Also, the maximum displacement amplitude was calculated as 0.191mm. Since these vibration levels are remarkably low, excessive vibration is not expected when the irradiation test of the instrumented capsule is performed at the HANARO core.

  6. Determination of D10 values of single and mixed cultures of bacteria after gamma irradiation

    International Nuclear Information System (INIS)

    Adu-Gyamfi, A.; Nketsia-Tabiri, J.; Boatin, R.

    2009-01-01

    The D 10 value of bacteria represents the absorbed radiation dose required to inactivate 90 % of a viable population or reduce the population by a factor of 10. D 10 values of 3 bacterial isolates (Escherichia coli, Staphylococcus aureus and Salmonella parathyphi B) were determined using single and mixed cultures to assess the effect of microbial competition on radiosensitivity. The isolates were inoculated into wakye substrate and exposed to γ-radiation doses of 0, 100, 300, 450, 600, 750, 850 Gy from a 6O Co source at a dose rate of 2.20 kGy/h in air. Enumeration of survivors of the isolates was carried out using serial dilution and pour plate methods. The surviving fraction of isolates decreased with increased irradiation doses. D 10 values of E. coli, S. aureus and S. parathyphi B were respectively 0.27, 0.33 and 0.44 kGy when inoculated as single cultures, and 0.24, 0.28 and 0.32 kGy respectively when inoculated as mixed cultures. D 10 values were lower for mixed cultures compared to single cultures, which might indicate reduced resistance to γ-radiation as a result of competition among the isolates. Microbiological challenge tests based on the D 10 values may result in delivery of higher irradiation doses, but the extra dose could serve as safety margin to enhance the food preservative capacity of radiation processing. (au)

  7. 77 FR 33227 - Assessment Questionnaire-IP Sector Specific Agency Risk Self Assessment Tool (IP-SSARSAT)

    Science.gov (United States)

    2012-06-05

    ... DEPARTMENT OF HOMELAND SECURITY [Docket No. DHS-2011-0069] Assessment Questionnaire--IP Sector... comments concerning new Information Collection Request--Assessment Questionnaire--IP Sector Specific Agency... http://www.regulations.gov , including any personal information provided. OMB is particularly...

  8. Improvement of the half-embryo test for detection of gamma-irradiated grapefruit and its application to irradiated oranges and lemons

    International Nuclear Information System (INIS)

    Kawamura, Y.; Uchiyama, S.; Saito, Y.

    1989-01-01

    The duration of the half-embryo test used for identification of gamma-irradiated grapefruit was shortened by increasing germination temperature to 35 degrees C. Maximum shooting percentages were reached within 3 days. Gibberellin application reduced the required incubation time to 2 days. Half-embryos extracted from irradiated orange and lemon gave similar results to those of grapefruit. This half-embryo test is proposed as an identification method for irradiated citrus. Assessment can be made after 3 to 4 days when shooting percentage is greater than 50%

  9. Part III: Comparing observed growth of selected test organisms in food irradiation studies with growth predictions calculated by ComBase softwares

    International Nuclear Information System (INIS)

    Farkas, J.; Andrassy, E.; Meszaros, L.; Beczner, J.; Polyak-Feher, K.; Gaal, O.; Lebovics, V.K.; Lugasi, A.

    2009-01-01

    As a result of intensive predictive microbiological modelling activities, several computer programs and softwares became available recently for facilitating microbiological risk assessment. Among these tools, the establishment of the ComBase, an international database and its predictive modelling softwares of the Pathogen Modelling Program (PMP) set up by the USDA Eastern Regional Research Center, Wyndmore, PA, and the Food Micromodel/Growth Predictor by the United Kingdom's Institute of Food Research, Norwich, are most important. The authors have used the PMP 6.1 software version of ComBase as a preliminary trial to compare observed growth of selected test organisms in relation to their food irradiation work during recent years within the FAO/IAEA Coordinated Food Irradiation Research Projects (D6.10.23 and D6.20.07) with the predicted growth on the basis of growth models available in ComBase for the same species as those of the authors' test organisms. The results of challenge tests with Listeria monocytogenes inoculum in untreated or irradiated experimental batches of semi-prepared breaded turkey meat steaks (cordon bleu), sliced tomato, sliced watermelon, sliced cantaloupe and sous vide processed mixed vegetables, as well as Staphylococcus aureus inoculum of a pasta product, tortellini, were compared with their respective growth models under relevant environmental conditions. This comparison showed good fits in the case of non-irradiated and high moisture food samples, but growth of radiation survivors lagged behind the predicted values. (author)

  10. Ataxia telangiectasia derived iPS cells show preserved x-ray sensitivity and decreased chromosomal instability

    OpenAIRE

    Fukawatase, Yoshihiro; Toyoda, Masashi; Okamura, Kohji; Nakamura, Ken-ichi; Nakabayashi, Kazuhiko; Takada, Shuji; Yamazaki-Inoue, Mayu; Masuda, Akira; Nasu, Michiyo; Hata, Kenichiro; Hanaoka, Kazunori; Higuchi, Akon; Takubo, Kaiyo; Umezawa, Akihiro

    2014-01-01

    Ataxia telangiectasia is a neurodegenerative inherited disease with chromosomal instability and hypersensitivity to ionizing radiation. iPS cells lacking ATM (AT-iPS cells) exhibited hypersensitivity to X-ray irradiation, one of the characteristics of the disease. While parental ataxia telangiectasia cells exhibited significant chromosomal abnormalities, AT-iPS cells did not show any chromosomal instability in vitro for at least 80 passages (560 days). Whole exome analysis also showed a compa...

  11. Aspheric surface testing by irradiance transport equation

    Science.gov (United States)

    Shomali, Ramin; Darudi, Ahmad; Nasiri, Sadollah; Asgharsharghi Bonab, Armir

    2010-10-01

    In this paper a method for aspheric surface testing is presented. The method is based on solving the Irradiance Transport Equation (ITE).The accuracy of ITE normally depends on the amount of the pick to valley of the phase distribution. This subject is investigated by a simulation procedure.

  12. Updated FY12 Ceramic Fuels Irradiation Test Plan

    International Nuclear Information System (INIS)

    Nelson, Andrew T.

    2012-01-01

    The Fuel Cycle Research and Development program is currently devoting resources to study of numerous fuel types with the aim of furthering understanding applicable to a range of reactors and fuel cycles. In FY11, effort within the ceramic fuels campaign focused on planning and preparation for a series of rabbit irradiations to be conducted at the High Flux Isotope Reactor located at Oak Ridge National Laboratory. The emphasis of these planned tests was to study the evolution of thermal conductivity in uranium dioxide and derivative compositions as a function of damage induced by neutron damage. Current fiscal realities have resulted in a scenario where completion of the planned rabbit irradiations is unlikely. Possibilities for execution of irradiation testing within the ceramic fuels campaign in the next several years will thus likely be restricted to avenues where strong synergies exist both within and outside the Fuel Cycle Research and Development program. Opportunities to augment the interests and needs of modeling, advanced characterization, and other campaigns present the most likely avenues for further work. These possibilities will be pursued with the hope of securing future funding. Utilization of synthetic microstructures prepared to better understand the most relevant actors encountered during irradiation of ceramic fuels thus represents the ceramic fuel campaign's most efficient means to enhance understanding of fuel response to burnup. This approach offers many of the favorable attributes embraced by the Separate Effects Testing paradigm, namely production of samples suitable to study specific, isolated phenomena. The recent success of xenon-imbedded thick films is representative of this approach. In the coming years, this strategy will be expanded to address a wider range of problems in conjunction with use of national user facilities novel characterization techniques to best utilize programmatic resources to support a science-based research program.

  13. Inference of hierarchical regulatory network of estrogen-dependent breast cancer through ChIP-based data

    Directory of Open Access Journals (Sweden)

    Parvin Jeffrey

    2010-12-01

    Full Text Available Abstract Background Global profiling of in vivo protein-DNA interactions using ChIP-based technologies has evolved rapidly in recent years. Although many genome-wide studies have identified thousands of ERα binding sites and have revealed the associated transcription factor (TF partners, such as AP1, FOXA1 and CEBP, little is known about ERα associated hierarchical transcriptional regulatory networks. Results In this study, we applied computational approaches to analyze three public available ChIP-based datasets: ChIP-seq, ChIP-PET and ChIP-chip, and to investigate the hierarchical regulatory network for ERα and ERα partner TFs regulation in estrogen-dependent breast cancer MCF7 cells. 16 common TFs and two common new TF partners (RORA and PITX2 were found among ChIP-seq, ChIP-chip and ChIP-PET datasets. The regulatory networks were constructed by scanning the ChIP-peak region with TF specific position weight matrix (PWM. A permutation test was performed to test the reliability of each connection of the network. We then used DREM software to perform gene ontology function analysis on the common genes. We found that FOS, PITX2, RORA and FOXA1 were involved in the up-regulated genes. We also conducted the ERα and Pol-II ChIP-seq experiments in tamoxifen resistance MCF7 cells (denoted as MCF7-T in this study and compared the difference between MCF7 and MCF7-T cells. The result showed very little overlap between these two cells in terms of targeted genes (21.2% of common genes and targeted TFs (25% of common TFs. The significant dissimilarity may indicate totally different transcriptional regulatory mechanisms between these two cancer cells. Conclusions Our study uncovers new estrogen-mediated regulatory networks by mining three ChIP-based data in MCF7 cells and ChIP-seq data in MCF7-T cells. We compared the different ChIP-based technologies as well as different breast cancer cells. Our computational analytical approach may guide biologists to

  14. Using cloud computing technologies in IP-video surveillance systems with the function of 3d-object modelling

    Directory of Open Access Journals (Sweden)

    Zhigalov Kirill

    2018-01-01

    Full Text Available This article is devoted to the integration of cloud technology functions into 3D IP video surveil-lance systems in order to conduct further video Analytics, incoming real-time data, as well as stored video materials on the server in the «cloud». The main attention is devoted to «cloud technologies» usage optimizing the process of recognition of the desired object by increasing the criteria of flexibility and scalability of the system. Transferring image load from the client to the cloud server, to the virtual part of the system. The development of the issues considered in the article in terms of data analysis, which will significantly improve the effectiveness of the implementation of special tasks facing special units.

  15. Survival of synchronized diploid yeast after ultraviolet irradiation

    International Nuclear Information System (INIS)

    Nunes, E.; Lorido, L.; Gelos, U.

    1975-01-01

    Synchronized populations of diploid yeast were exposed to uv light and their survival thereafter upon immediate plating (IP) and after liquid holding (LH) treatment in the presence and absence of caffeine was examined. These cells were found to be most resistant to uv light during early budding (G 2 period). The effect of LH is positive throughout the cell cycle and is dependent on the radiosensitivity of the cells upon IP. Caffeine-sensitive and caffeine-insensitive components of dark repair were demonstrated. The uv light responses of logarithmic growing and synchronized populations were compared with x-ray responses of the same strain analyzed under the same conditions in a previous work. The pattern of variation in sensitivity throughout the cell cycle and the ability to recover are qualitatively similar. The caffeine-insensitive component of repair has a similar efficiency in uv and x-irradiated G 1 cells, increasing in uv-irradiated cells after the beginning of the DNA synthetic period and during the G 2 period. The findings observed under IP conditions are consistent with a model already proposed which requires the repair efficiency to oscillate during the cell cycle. The results suggest that repair pathways for lethal uv damage may share some common steps with those for x-ray damage

  16. Comparison of fracture behavior for low-swelling ferritic and austenitic alloys irradiated in the Fast Flux Test Facility (FFTF) to 180 DPA

    International Nuclear Information System (INIS)

    Huang, F.H.

    1992-02-01

    Fracture toughness testing was conducted to investigate the radiation embrittlement of high-nickel superalloys, modified austenitic steels and ferritic steels. These materials have been experimentally proven to possess excellent resistance to void swelling after high neutron exposures. In addition to swelling resistance, post-irradiation fracture resistance is another important criterion for reactor material selection. By means of fracture mechanics techniques the fracture behavior of those highly irradiated alloys was characterized in terms of irradiation and test conditions. Precipitation-strengthened alloys failed by channel fracture with very low postirradiation ductility. The fracture toughness of titanium-modified austenitic stainless steel D9 deteriorates with increasing fluence to about 100 displacement per atom (dpa), the fluence level at which brittle fracture appears to occur. Ferritic steels such as HT9 are the most promising candidate materials for fast and fusion reactor applications. The upper-shelf fracture toughness of alloy HT9 remained adequate after irradiation to 180 dpa although its ductile- brittle transition temperature (DBTT) shift by low temperature irradiation rendered the material susceptible to brittle fracture at room temperature. Understanding the fracture characteristics under various irradiation and test conditions helps reduce the potential for brittle fracture by permitting appropriate measure to be taken

  17. Determination of the mechanical characteristics of irradiated metals from the results of microhardness tests

    International Nuclear Information System (INIS)

    Hofman, A.

    1999-01-01

    To predict the possibilities of using structural materials in nuclear and thermonuclear reactors, it is important to have data on changes of the mechanical characteristics and irradiation obtained from full-scale or simulation tests. Materials are irradiated in nuclear reactors with fast neutrons, the sources of high-energy neutrons with an energy of 14 MeV and the accelerators of charged particles. The restricted volumes for irradiation of these specimens in the systems and also the need to test large numbers of specimens under the same conditions make it necessary to reduce the size of irradiated specimens. To solve this problem, work is being carried out to develop various methods of testing miniature specimens, including tension extrusion of disc-shaped micro-specimens, microhardness, and the Charpy Method. In examination of the irradiation hardening of the materials, the main advantage of the microhardness method is that it makes it possible to examine small specimens. In single microhardness tests, only a small area of the irradiated specimens is examined. This makes it possible to increase the radiation dose and carry out subsequent tests of microhardness on the same specimens. The aim of this work was to determine the possibilities of using the microhardness measurement method for evaluating the mechanical characteristics of metallic materials. The comparison of the data, obtained in microhardness tests and in tensile loading specimens of 0Kh18N10Tsteel, irradiated with neutrons, shows the efficiency of the microhardness method as a tool for investigating the irradiation hardening of reactor materials

  18. Fission gas induced deformation model for FRAP-T6 and NSRR irradiated fuel test simulations

    Energy Technology Data Exchange (ETDEWEB)

    Nakamura, Takehiko; Sasajima, Hideo; Fuketa, Toyoshi [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment; Hosoyamada, Ryuji; Mori, Yukihide

    1996-11-01

    Pulse irradiation tests of irradiated fuels under simulated reactivity initiated accidents (RIAs) have been carried out at the Nuclear Safety Research Reactor (NSRR). Larger cladding diameter increase was observed in the irradiated fuel tests than in the previous fresh fuel tests. A fission gas induced cladding deformation model was developed and installed in a fuel behavior analysis code, FRAP-T6. The irradiated fuel tests were analyzed with the model in combination with modified material properties and fuel cracking models. In Test JM-4, where the cladding temperature rose to higher temperatures and grain boundary separation by the pulse irradiation was significant, the fission gas model described the cladding deformation reasonably well. The fuel had relatively flat radial power distribution and the grain boundary gas from the whole radius was calculated to contribute to the deformation. On the other hand, the power density in the irradiated LWR fuel rods in the pulse irradiation tests was remarkably higher at the fuel periphery than the center. A fuel thermal expansion model, GAPCON, which took account of the effect of fuel cracking by the temperature profile, was found to reproduce well the LWR fuel behavior with the fission gas deformation model. This report present details of the models and their NSRR test simulations. (author)

  19. Present status of irradiation tests on tritium breeding blanket for fusion reactor

    International Nuclear Information System (INIS)

    Futamura, Yoshiaki; Sagawa, Hisashi; Shimakawa, Satoshi; Tsuchiya, Kunihiko; Kuroda, Toshimasa; Kawamura, Hiroshi.

    1994-01-01

    To develop a tritium breeding blanket for a fusion reactor, irradiation tests in fission reactors are indispensable for obtaining data on irradiation effects on materials, and neutronics/thermal characteristics and tritium production/recovery performance of the blanket. Various irradiation tests have been conducted in the world, especially to investigate tritium release characteristics from tritium breeding and neutron multiplier materials, and materials integrity under irradiation. In Japan, VOM experiments at JRR-2 for ceramic breeders and experiments at JMTR for ceramic breeders and beryllium as a neutron multiplier have been performed. Several universities have also investigated ceramic breeders. In the EC, the EXOTIC experiments at HFR in the Netherlands and the SIBELIUS, the LILA, the LISA and the MOZART experiments for ceramic breeders have carried out. In Canada, NRU has been used for the CRITIC experiments. The TRIO experiments at ORR(ORNL), experiments at RTNS-II, FUBR and ATR have been conducted in the USA. The last two are experiments with high neutron fluence aiming at investigating materials integrity under irradiation. The BEATRIX-I and -II experiments have proceeded under international collaboration of Japan, Canada, the EC and the USA. This report shows the present status of these irradiation tests following a review of the blanket design in the ITER CDA(Conceptual Design Activity). (author)

  20. Analysis on the post-irradiation examination of the HANARO miniplate-1 irradiation test for Kijang research reactor

    Energy Technology Data Exchange (ETDEWEB)

    Park, Jong Man; Tahk, Young Wook; Jeong, Yong Jin [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of); and others

    2017-08-15

    The construction project of the Kijang research reactor (KJRR), which is the second research reactor in Korea, has been launched. The KJRR was designed to use, for the first time, U–Mo fuel. Plate-type U–7 wt.% Mo/Al–5 wt.% Si, referred to as U–7Mo/Al–5Si, dispersion fuel with a uranium loading of 8.0 gU/cm{sup 3}, was selected to achieve higher fuel efficiency and performance than are possible when using U{sub 3}Si{sub 2}/Al dispersion fuel. To qualify the U–Mo fuel in terms of plate geometry, the first miniplates [HANARO Miniplate (HAMP-1)], containing U–7Mo/Al–5Si dispersion fuel (8 gU/cm{sup 3}), were fabricated at the Korea Atomic Energy Research Institute and recently irradiated at HANARO. The PIE (Post-irradiation Examination) results of the HAMP-1 irradiation test were analyzed in depth in order to verify the safe in-pile performance of the U–7Mo/Al–5Si dispersion fuel under the KJRR irradiation conditions. Nondestructive analyses included visual inspection, gamma spectrometric mapping, and two-dimensional measurements of the plate thickness and oxide thickness. Destructive PIE work was also carried out, focusing on characterization of the microstructural behavior using optical microscopy and scanning electron microscopy. Electron probe microanalysis was also used to measure the elemental concentrations in the interaction layer formed between the U–Mo kernels and the matrix. A blistering threshold test and a bending test were performed on the irradiated HAMP-1 miniplates that were saved from the destructive tests. Swelling evaluation of the U–Mo fuel was also conducted using two methods: plate thickness measurement and meat thickness measurement.

  1. Analysis on the post-irradiation examination of the HANARO miniplate-1 irradiation test for kijang research reactor

    Directory of Open Access Journals (Sweden)

    Jong Man Park

    2017-08-01

    Full Text Available The construction project of the Kijang research reactor (KJRR, which is the second research reactor in Korea, has been launched. The KJRR was designed to use, for the first time, U–Mo fuel. Plate-type U–7 wt.% Mo/Al–5 wt.% Si, referred to as U–7Mo/Al–5Si, dispersion fuel with a uranium loading of 8.0 gU/cm3, was selected to achieve higher fuel efficiency and performance than are possible when using U3Si2/Al dispersion fuel. To qualify the U–Mo fuel in terms of plate geometry, the first miniplates [HANARO Miniplate (HAMP-1], containing U–7Mo/Al–5Si dispersion fuel (8 gU/cm3, were fabricated at the Korea Atomic Energy Research Institute and recently irradiated at HANARO. The PIE (Post-irradiation Examination results of the HAMP-1 irradiation test were analyzed in depth in order to verify the safe in-pile performance of the U–7Mo/Al–5Si dispersion fuel under the KJRR irradiation conditions. Nondestructive analyses included visual inspection, gamma spectrometric mapping, and two-dimensional measurements of the plate thickness and oxide thickness. Destructive PIE work was also carried out, focusing on characterization of the microstructural behavior using optical microscopy and scanning electron microscopy. Electron probe microanalysis was also used to measure the elemental concentrations in the interaction layer formed between the U–Mo kernels and the matrix. A blistering threshold test and a bending test were performed on the irradiated HAMP-1 miniplates that were saved from the destructive tests. Swelling evaluation of the U–Mo fuel was also conducted using two methods: plate thickness measurement and meat thickness measurement.

  2. 21 CFR 582.40 - Natural extractives (solvent-free) used in conjunction with spices, seasonings, and flavorings.

    Science.gov (United States)

    2010-04-01

    ... conjunction with spices, seasonings, and flavorings. 582.40 Section 582.40 Food and Drugs FOOD AND DRUG... in conjunction with spices, seasonings, and flavorings. Natural extractives (solvent-free) used in conjunction with spices, seasonings, and flavorings that are generally recognized as safe for their intended...

  3. Irradiation tests of THTR fuel elements in the DRAGON reactor (irradiation experiment DR-K3)

    International Nuclear Information System (INIS)

    Burck, W.; Duwe, R.; Groos, E.; Mueller, H.

    1977-03-01

    Within the scope of the program 'Development of Spherical Fuel Elements for HTR', similar fuel elements (f.e.) have been irradiated in the DRAGON reactor. The f.e. were fabricated by NUKEM and were to be tested under HTR conditions to scrutinize their employability in the THTR. The fuel was in the form of coated particles moulded into A3 matrix. The kernels of the particles were made of mixed oxide of uranium and thorium with an U 235 enrichment of 90%. One aim of the post irradiation examination was the investigation of irradiation induced changes of mechanical properties (dimensional stability and elastic behaviour) and of the corrosion behaviour which were compared with the properties determined with unirradiated f.e. The measurement of the fission gas release in annealing tests and ceramografic examinations exhibited no damage of the coated particles. The measured concentration distribution of fission metals led to conclusions about their release. All results showed, that neither the coated particles nor the integral fuel spheres experienced any significant changes that could impair their utilization in the THTR. (orig./UA) [de

  4. Measurements of integrated components' parameters versus irradiation doses gamma radiation (60Co) dosimetry-methodology-tests

    International Nuclear Information System (INIS)

    Fuan, J.

    1991-01-01

    This paper describes the methodology used for the irradiation of the integrated components and the measurements of their parameters, using Quality Insurance of dosimetry: - Measurement of the integrated dose using the competences of the Laboratoire Central des Industries Electriques (LCIE): - Measurement of irradiation dose versus source/component distance, using a calibrated equipment. - Use of ALANINE dosimeters, placed on the support of the irradiated components. - Assembly and polarization of components during the irradiations. Selection of the irradiator. - Measurement of the irradiated components's parameters, using the competences of the societies: - GenRad: GR130 tests equipement placed in the DEIN/SIR-CEN SACLAY. - Laboratoire Central des Industries Electriques (LCIE): GR125 tests equipment and this associated programmes test [fr

  5. TEM in situ micropillar compression tests of ion irradiated oxide dispersion strengthened alloy

    Energy Technology Data Exchange (ETDEWEB)

    Yano, K.H., E-mail: kaylayano@u.boisestate.edu [Boise State University, 1910 University Drive, Boise, ID, 83725 (United States); Swenson, M.J. [Boise State University, 1910 University Drive, Boise, ID, 83725 (United States); Wu, Y. [Boise State University, 1910 University Drive, Boise, ID, 83725 (United States); Center for Advanced Energy Studies, 995 University Blvd, Idaho Falls, ID, 83401 (United States); Wharry, J.P. [Boise State University, 1910 University Drive, Boise, ID, 83725 (United States); Purdue University, 400 Central Drive, West Lafayette, IN 47907 (United States)

    2017-01-15

    The growing role of charged particle irradiation in the evaluation of nuclear reactor candidate materials requires the development of novel methods to assess mechanical properties in near-surface irradiation damage layers just a few micrometers thick. In situ transmission electron microscopic (TEM) mechanical testing is one such promising method. In this work, microcompression pillars are fabricated from a Fe{sup 2+} ion irradiated bulk specimen of a model Fe-9%Cr oxide dispersion strengthened (ODS) alloy. Yield strengths measured directly from TEM in situ compression tests are within expected values, and are consistent with predictions based on the irradiated microstructure. Measured elastic modulus values, once adjusted for the amount of deformation and deflection in the base material, are also within the expected range. A pillar size effect is only observed in samples with minimum dimension ≤100 nm due to the low inter-obstacle spacing in the as received and irradiated material. TEM in situ micropillar compression tests hold great promise for quantitatively determining mechanical properties of shallow ion-irradiated layers.

  6. Structural performance of an IP2 package in free drop test conditions: Numerical and experimental evaluations

    International Nuclear Information System (INIS)

    Lo Frano, Rosa; Pugliese, Giovanni; Nasta, Marco

    2014-01-01

    Highlights: • Vertical free drop test. • Qualification of an IP2 type Italian packaging. • Numerical and experimental investigation of the package integrity. • Demonstration the Italian packaging meets safety requirements. - Abstract: The casks or packaging systems used for the transportation of nuclear materials, especially spent fuel elements, have to be designed according to rigorous acceptance requirements, like the IAEA ones, in order to provide protection to human beings and environment against radiation exposure and contamination. This study deals with the free drop test of an Italian design packaging system to be used for the transportation of low and intermediate level radioactive wastes. Impact drop experiments were performed in the Lab. Scalbatraio of the DICI – University of Pisa. Dynamic analyses too have been carried out, by refined models of both the cask and target surface to predict the effects of the impact shock (vertical drop) on the package. The experimental tests and numerical analyses are thoroughly compared, presented and discussed. The numerical approach shows to be suitable to reproduce with good reliability the test situations and results

  7. HFR irradiation testing of light water reactor (LWR) fuel

    International Nuclear Information System (INIS)

    Markgraf, J.F.W.

    1985-01-01

    For the materials testing reactor HFR some characteristic information with emphasis on LWR fuel rod testing capabilities and hot cell investigation is presented. Additionally a summary of LWR fuel irradiation programmes performed and forthcoming programmes are described. Project management information and a list of publications pertaining to LWR fuel rod test programmes is given

  8. Inositol hexakisphosphate (IP6) generated by IP5K mediates cullin-COP9 signalosome interactions and CRL function.

    Science.gov (United States)

    Scherer, Paul C; Ding, Yan; Liu, Zhiqing; Xu, Jing; Mao, Haibin; Barrow, James C; Wei, Ning; Zheng, Ning; Snyder, Solomon H; Rao, Feng

    2016-03-29

    The family of cullin-RING E3 Ligases (CRLs) and the constitutive photomorphogenesis 9 (COP9) signalosome (CSN) form dynamic complexes that mediate ubiquitylation of 20% of the proteome, yet regulation of their assembly/disassembly remains poorly understood. Inositol polyphosphates are highly conserved signaling molecules implicated in diverse cellular processes. We now report that inositol hexakisphosphate (IP6) is a major physiologic determinant of the CRL-CSN interface, which includes a hitherto unidentified electrostatic interaction between the N-terminal acidic tail of CSN subunit 2 (CSN2) and a conserved basic canyon on cullins. IP6, with an EC50 of 20 nM, acts as an intermolecular "glue," increasing cullin-CSN2 binding affinity by 30-fold, thereby promoting assembly of the inactive CRL-CSN complexes. The IP6 synthase, Ins(1,3,4,5,6)P5 2-kinase (IPPK/IP5K) binds to cullins. Depleting IP5K increases the percentage of neddylated, active Cul1 and Cul4A, and decreases levels of the Cul1/4A substrates p27 and p21. Besides dysregulating CRL-mediated cell proliferation and UV-induced apoptosis, IP5K depletion potentiates by 28-fold the cytotoxic effect of the neddylation inhibitor MLN4924. Thus, IP5K and IP6 are evolutionarily conserved components of the CRL-CSN system and are potential targets for cancer therapy in conjunction with MLN4924.

  9. Comparison of properties and microstructures of Trefimetaux CuNiBe and Hycon 3HP {sup TM} before and after neutron irradiation. (ITER R and D Task no. T213)

    Energy Technology Data Exchange (ETDEWEB)

    Edwards, D.J. [Pacific Northwest National Lab., Materials Development. Group, Richland (United States); Eldrup, M.; Toft, P.; Singh, B.N

    2000-07-01

    The precipitation strengthened CuNiBe alloys are among the three candidate copper alloys that are being evaluated for application in the first wall, divertor, and limiter components of ITER. Generally, CuNiBe alloys have higher strength but poorer conductivity compared to CuCrZr and Cu-A1{sub 2}O{sub 3} alloys. Brush-Wellman Inc. has developed an improved version of their Hycon CuNiBe alloy that has higher conductivity while maintaining a reasonable level of strength. In the present work we have investigated the physical and mechanical properties of the Hycon 3HP{sup TM} alloy both before and after neutron irradiation and have compared its microstructure and properties with the European CuNiBe candidate alloy manufactured by Trefimetaux. Tensile specimens of both alloys were irradiated in the DR-3 reactor at Risoe to displacement dose levels of up to 0.3 dpa at 100, 250 and 350 {sup d}eg{sup C}. Both alloys were tensile tested in vacuum in the unirradiated and irradiated conditions at 100, 250 and 350 {sup d}eg{sup C} and the microstructures of the alloys were investigated using transmission electron microscopy. Electrical resistivity measurements were made on tensile specimens be-fore and after irradiation; all measurements were made at 23 {sup d}eg{sup C}. Results of these investigations are presented and discussed in terms of the sensitivity of these alloys to test temperature, which becomes increasingly problematic when the irradiation and test temperature reaches 250 {sup d}eg{sup C} and above. (au)

  10. Market testing of irradiated food

    International Nuclear Information System (INIS)

    Duc, Ho Minh

    2001-01-01

    Viet Nam has emerged as one of the three top producers and exporters of rice in the world. Tropical climate and poor infrastructure of preservation and storage lead to huge losses of food grains, onions, dried fish and fishery products. Based on demonstration irradiation facility pilot scale studies and marketing of irradiated rice, onions, mushrooms and litchi were successfully undertaken in Viet Nam during 1992-1998. Irradiation technology is being used commercially in Viet Nam since 1991 for insect control of imported tobacco and mould control of national traditional medicinal herbs by both government and private sectors. About 30 tons of tobacco and 25 tons of herbs are irradiated annually. Hanoi Irradiation Centre has been continuing open house practices for visitors from school, universities and various different organizations and thus contributed in improved public education. Consumers were found to prefer irradiated rice, onions, litchi and mushrooms over those nonirradiated. (author)

  11. Application of half-embryo test to irradiated apples and cherries

    International Nuclear Information System (INIS)

    Kawamura, Yoko; Miura, Aya; Sugita, Takiko; Yamada, Takashi; Saito, Yukio

    1995-01-01

    The half-embryo test was applied to irradiated apples and cherries. The optimum incubation temperature for apples and cherries was 30 o C and 25 o C, respectively. Benzyladenine stimulated the shooting of cherry half-embryos, therefore, they were incubated with 10 μM benzyladenine. The irradiation of apples and cherries caused obvious changes in the growth of the half-embryos. A dose of 0.15 kGy or more almost totally retarded shoot elongation. If shooting is less than 50%, the apples and cherries are identified as ''irradiated''. An assessment could be made after 1 to 4 days and the detection limit of the irradiation dose is 0.15 kGy. (author)

  12. IP Security für Linux

    OpenAIRE

    Parthey, Mirko

    2001-01-01

    Die Nutzung des Internet für sicherheitskritische Anwendungen erfordert kryptographische Schutzmechanismen. IP Security (IPsec) definiert dafür geeignete Protokolle. Diese Arbeit gibt einen Überblick über IPsec. Eine IPsec-Implementierung für Linux (FreeS/WAN) wird auf Erweiterbarkeit und Praxistauglichkeit untersucht. Using the Internet in security-critical areas requires cryptographic protection, for which IP Security (IPsec) defines suitable protocols. This paper gives an overview of IP...

  13. Design and fabrication report on capsule (11M 19K for out of pile test) for irradiation testing of research reactor materials at HANARO

    Energy Technology Data Exchange (ETDEWEB)

    Kim, B.G.; Yang, S.W.; Park, S.J.; Shim, K.T.; Choo, K.N.; Oh, J.M.; Lee, B.C.; Choi, M.H.; Kim, D.J.; Kim, J.M.; Kang, S.H.; Chun, Y.B.; Kim, T.K.; Jeong, Y.H.

    2012-05-15

    As a part of the research reactor development project with a plate type fuel, the irradiation tests of graphite (Gr), beryllium (Be), and zircaloy 4 materials using the capsule have been investigating to obtain the mechanical characteristics such as an irradiation growth, hardness, swelling and tensile strength at the temperature below 100 .deg. C and the 30 MW reactor power. Then, A capsule to be able to irradiate materials(graphite, Be, zircaloy 4) under 100 .deg. C at the HANARO was designed and fabricated. After performing out of pile testing in single channel test loop by using the capsule, the final design of the capsules to be irradiated in CT and IR2 test hole of HANARO was approved, and 2 sets of capsule were fabricated. These capsules will be loaded in CT and IR2 test hole of HANARO, and be started the irradiation from the end of June, 2012. After performing the irradiation testing of 2 sets of capsule, PIE (Post Irradiation Examination) on irradiated specimens (Gr, Be, and zircaloy 4) will be carry out in IMEF (Irradiated Material Examination Facility). So, the irradiation testing will be contributed to obtain the characteristic data induced neutron irradiation on Gr, Be, and zircaloy 4. And then, it is convinced that these data will be also contributed to obtain the license for JRTR (Jordan Research and Training Reactor) and new research reactor in Korea, and export research reactors.

  14. IP-10 measured by Dry Plasma Spots as biomarker for therapy responses in Mycobacterium Tuberculosis infection.

    Science.gov (United States)

    Tonby, Kristian; Ruhwald, Morten; Kvale, Dag; Dyrhol-Riise, Anne Ma

    2015-03-18

    Tuberculosis (TB) has huge impact on human morbidity and mortality and biomarkers to support rapid TB diagnosis and ensure treatment initiation and cure are needed, especially in regions with high prevalence of multi-drug resistant TB. Soluble interferon gamma inducible protein 10 (IP-10) analyzed from dry plasma spots (DPS) has potential as an immunodiagnostic marker in TB infection. We analyzed IP-10 levels in plasma directly and extracted from DPS in parallel by ELISA from 34 clinically well characterized patients with TB disease before and throughout 24 weeks of effective anti-TB chemotherapy. We detected a significant decline of IP-10 levels in both plasma and DPS already after two weeks of therapy with good correlation between the tests. This was observed both in pulmonary and extrapulmonary TB. In conclusion, plasma IP-10 may serve as an early biomarker for anti-TB chemotherapy responses and the IP-10 DPS method has potential to be developed into a point-of care test for use in resource-limited settings. Further studies must be performed to validate the use of IP-10 DPS in TB high endemic countries.

  15. CMT: a constrained multi-level thresholding approach for ChIP-Seq data analysis.

    Directory of Open Access Journals (Sweden)

    Iman Rezaeian

    Full Text Available Genome-wide profiling of DNA-binding proteins using ChIP-Seq has emerged as an alternative to ChIP-chip methods. ChIP-Seq technology offers many advantages over ChIP-chip arrays, including but not limited to less noise, higher resolution, and more coverage. Several algorithms have been developed to take advantage of these abilities and find enriched regions by analyzing ChIP-Seq data. However, the complexity of analyzing various patterns of ChIP-Seq signals still needs the development of new algorithms. Most current algorithms use various heuristics to detect regions accurately. However, despite how many formulations are available, it is still difficult to accurately determine individual peaks corresponding to each binding event. We developed Constrained Multi-level Thresholding (CMT, an algorithm used to detect enriched regions on ChIP-Seq data. CMT employs a constraint-based module that can target regions within a specific range. We show that CMT has higher accuracy in detecting enriched regions (peaks by objectively assessing its performance relative to other previously proposed peak finders. This is shown by testing three algorithms on the well-known FoxA1 Data set, four transcription factors (with a total of six antibodies for Drosophila melanogaster and the H3K4ac antibody dataset.

  16. Creep test under irradiation with thermal gradient for the cylindrical carbon fiber reinforced carbon composite. Interim report on irradiation examinations: 03M-47AS

    International Nuclear Information System (INIS)

    Baba, Shin-ichi; Sawa, Kazuhiro; Yamaji, Masatoshi; Matsui, Yoshinori; Ishihara, Masahiro

    2007-03-01

    The creep test under irradiation with thermal gradient for the cylindrical carbon fiber reinforced carbon composites (c/c composite) are carried out in the Japan Material Testing Reactor (JMTR). This report described 4-items; first item is design/evaluation of the capsule for the irradiation test, second is before irradiation measurements for the residual strain due to manufactured cylindrical c/c composite, and third is also before irradiation measurements of the distance between 2-holes of predrilled in the specimen and last item is examination of analysis for the irradiation creep with thermal gradient by VIENUS Code. The normal creep test is static mechanical load on the specimen in thermal condition, but this creep test under irradiation capsule is thermal stress due to thermal gradient at inside specimen in the thermal condition. Consequently, it is necessary as large as possible thermal gradient in the narrow space of the capsule inside volume. In which the tungsten rod (W-rod) was inserted to the cylindrical c/c composite specimen, for γ-ray heat generation density occurred highly and so maximize the difference temperatures of surface wall between inside and outside wall of the specimen. The measurement method of the deflection due to the irradiation creep of cylindrical c/c composite was adopted as way of ruptured the specimen among the predrilled distance of 2-holes before/after irradiation. Accordingly as the laser dimensional apparatus used to measure the distance between the 2-holes of specimen exactly, easy and untouchable. And also before irradiation measurement of the residual stress due to the manufactured process was estimated by neutron diffraction used Residual Stress Analyzer (RESA) at JRR-3M in JAEA. The irradiation test was finished as total irradiation time, average temperature and neutron dose showed 4189 hours, 873 K and 8.2x10 24 (E>1.0MeV:m -2 ) respectively. The thermal stress was estimated by the difference temperatures of 4

  17. Irradiation induced crossover from 1D to 3D transport behaviors of PEDOT-titanium dioxide hybrid nanocomposites

    Energy Technology Data Exchange (ETDEWEB)

    Sarmah, Smritimala [Department of Physics, Girijananda Chowdhury Institute of Management and Technology, Guwahati 781017, Assam (India); Kumar, A. [Materials Research Laboratory, Department of Physics, Tezpur University, Tezpur 784028, Assam (India)

    2012-12-15

    Conductive poly(3,4-ethylenedioxythiophene)/TiO{sub 2} nanocomposites were synthesized via a facile oxidative polymerization approach using dodecylbenzene sulfonic acid as a dopant and ammonium peroxydisulfate as an oxidant and irradiated with 90 MeV O{sup 7+} ions at the fluences of 5 x 10{sup 10}, 1 x 10{sup 11}, 5 x 10{sup 11}, and 1 x 10{sup 12} ions cm{sup -2} using 15UD Pelletron accelerator under high vacuum. X-ray diffraction studies show that microstrain and domain crystallite size of the nanocomposites increases with the increase of ion fluence resulting in highly ordered PEDOT-TiO{sub 2} nanocomposites. Thermogravimmetric analysis shows that the thermal stability of the nanocomposites increases with the increase of irradiation fluences which can be attributed to the crosslinking of polymer chains due to high electronic energy deposition. Scanning electron micrographs show that there is grain growth after swift heavy ion (SHI) irradiation resulting highly dense and less porous microstructure of nanocomposite films. DC conductivity of unirradiated nanocomposites exhibits Mott's 1D variable range hopping (VRH) mechanism. However, there is cross over to 3D VRH mechanism at higher irradiation fluence of 5 x 10{sup 11} and 1 x 10{sup 12} ions cm{sup -2}. There is an enhancement in the electrical conductivity of the nanocomposites upon SHI irradiation correlating crosslinking with DC conductivity of the nanocomposites. (Copyright copyright 2012 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  18. Factors associated with pulmonary toxicity after myeloablative conditioning using fractionated total body irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Byun, Hwa Kyung; Yoon, Hong In; Cho, Jae Ho [Yonsei Cancer Center, Yonsei University College of Medicine, Seoul (Korea, Republic of); and others

    2017-09-15

    Pulmonary toxicities, including infectious pneumonia (IP) and idiopathic pneumonia syndrome (IPS), are serious side effects of total body irradiation (TBI) used for myeloablative conditioning. This study aimed to evaluate clinical factors associated with IP and IPS following TBI. Fifty-eight patients with hematologic malignancies who underwent TBI before allogeneic hematopoietic stem cell transplantation between 2005 and 2014 were reviewed. Most patients (91%) received 12 Gy in 1.5 Gy fractions twice a day. Pulmonary toxicities were diagnosed based on either radiographic evidence or reduced pulmonary function, and were subdivided into IP and IPS based on the presence or absence of concurrent infection. Pulmonary toxicities developed in 36 patients (62%); 16 (28%) had IP and 20 (34%) had IPS. IP was significantly associated with increased treatment-related mortality (p = 0.028) and decreased survival (p = 0.039). Multivariate analysis revealed that the risk of developing IPS was significantly higher in patients who received stem cells from a matched unrelated donor than from a matched sibling donor (p = 0.021; hazard ratio [HR] = 12.67; 95% confidence interval [CI], 1.46–110.30). Combining other conditioning agents with cyclophosphamide produced a higher tendency to develop IP (p = 0.064; HR = 6.19; 95% CI, 0.90–42.56). IP and IPS involve different risk factors and distinct pathogeneses that should be considered when planning treatments before and after TBI.

  19. Factors associated with pulmonary toxicity after myeloablative conditioning using fractionated total body irradiation

    International Nuclear Information System (INIS)

    Byun, Hwa Kyung; Yoon, Hong In; Cho, Jae Ho

    2017-01-01

    Pulmonary toxicities, including infectious pneumonia (IP) and idiopathic pneumonia syndrome (IPS), are serious side effects of total body irradiation (TBI) used for myeloablative conditioning. This study aimed to evaluate clinical factors associated with IP and IPS following TBI. Fifty-eight patients with hematologic malignancies who underwent TBI before allogeneic hematopoietic stem cell transplantation between 2005 and 2014 were reviewed. Most patients (91%) received 12 Gy in 1.5 Gy fractions twice a day. Pulmonary toxicities were diagnosed based on either radiographic evidence or reduced pulmonary function, and were subdivided into IP and IPS based on the presence or absence of concurrent infection. Pulmonary toxicities developed in 36 patients (62%); 16 (28%) had IP and 20 (34%) had IPS. IP was significantly associated with increased treatment-related mortality (p = 0.028) and decreased survival (p = 0.039). Multivariate analysis revealed that the risk of developing IPS was significantly higher in patients who received stem cells from a matched unrelated donor than from a matched sibling donor (p = 0.021; hazard ratio [HR] = 12.67; 95% confidence interval [CI], 1.46–110.30). Combining other conditioning agents with cyclophosphamide produced a higher tendency to develop IP (p = 0.064; HR = 6.19; 95% CI, 0.90–42.56). IP and IPS involve different risk factors and distinct pathogeneses that should be considered when planning treatments before and after TBI

  20. Evaluation tests of treatment planning systems concerning 3D dose calculation

    International Nuclear Information System (INIS)

    Simonian-Sauve, M.; Smart, C.

    1998-01-01

    The development of irradiation techniques in radiotherapy shows a clear tendency towards the systematic use of three-dimensional (3D) information. Great efforts are being made to set up 3D conformal radiotherapy. Consequently, in the aim of greater coherence and accuracy, 'the dosimetric tool' must also meet the requirements of 3D radiotherapy, as it plays a role in the treatment chain. To know if the treatment planning system is a '3D', '2D', or even '1D' system, one should not be satisfied with reading the technical documentation and the program algorithm description not entirely trust the constructor's assertions. It is essential to clearly and precisely evaluate the possibilities of the treatment planning system. Even if it is proved not to satisfy perfectly all the tests which would qualify it as a real 3D calculation system, the study of the test results helps to give clear explanations of the dosimetric results. Two series of test cases are proposed. The first series allows us to understand in which conditions the treatment planning system takes into account the scatter influence in a volume. The second series is designed to inform us about the capacity of the dose calculation algorithm when the medium encloses non-homogeneities. These test cases do not constitute an exhaustive 'check-list' able to tackle completely the question of 3D calculation. They are submitted as examples and should be considered as an evaluation methodology for the software implanted in the treatment planning system. (authors)