Sample records for terramycin

  1. Effects of severe chronic scrotal Dermatophilus congolensis (kirchi) infection on semen characteristics in Zebu/Friesian crossbred bulls and effect of long-acting terramycin chemotherapy. (United States)

    Sekoni, V O


    The semen characteristics of 12 Zebu/Friesian crossbred bulls, aged 2 to 3 years, were studied during a 21-month period. At the 12th month of the study, the commencement of the rainy season, the bulls were infected naturally with Dermatophilus congolensis . Lesions were scattered over the body and limbs, but were particularly pronounced on the scrotum. Monthly treatments with injection of terramycin were begun as soon as lesions were detected and continued until the end of the study. The lesions worsened and became pronounced particularly on the scrotum of all the bulls. Scrotal scab formation caused by infection became prominent at the 14th month of the study. Until that period, the bulls had normal semen characteristics. From the 15th month until the end of the study, there was progressive deterioration of semen characteristics in all the bulls; this was manifested by some or all of the following effects: decreased volume, increased percentage of dead spermatozoa, increased percentage of total sperm morphological abnormalities, decreased percentage of progressively motile spermatozoa, oligospermia and terminal azoospermia. Therefore, severe chronic scrotal dermatophilosis may be a significant cause of infertility or sterility in bulls.

  2. [Dermatophilus congolensis infection in Brandenburg]. (United States)

    Köhler, B; Puls, H


    At first time Dermatophilus (D.) congolensis-infection was diagnosed in Brandenburg in 3 sheep herds and in one horse, which had contact to diseased sheep. The causative agent was introduced from West-Germany probably. Cause of the disease was influenced by a longer rain period and by secondary infections through Staph. aureus var. ovis. The morbidity came up to 90%, the mortality of lambs was 10%. Clinical picture, diagnostic and control of the disease are described. Economical losses are caused by disturbances of the development and deaths of animals mainly. Treatment of sheep was successful with Terramycin LA or 200 mg Oxytetracycline by i.m. injection of 1 ml within 7 days. All isolated strains of D. congolensis caused beta-hemolysis and liquidation of Löffler-Medium (heated denatured serum of cattle), and gelatin and fermented glucose and fructose to acid.

  3. Contribuição para o conhecimento das doenças do grupo tifo exantemático do Brasil

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    Octavio de Magalhães


    Full Text Available In this work the author publishes an observation of a human case, which he believes to be the second in South America, of "Q" fever in Minas Gerais. The first positive data and the first observation were made in S. Paulo by Dr. Helvecio Brandão and there communicated to the S. Paulo Medical Association in 1951 and 1954. The first part was published in 1953; the second part is yet unpublished. The author of the present work cured his patient with Terramycine. He thinks that greater research should be made amongst the workpeople who have to do with cattle in the pastures and slaughterhouses in order to verify the extent of the disease amongst us. Belo Horizonte Dezembro de 1954

  4. Further data to the aetiology, pathogenesis and therapy of infectious bovine keratoconjunctivitis. (United States)

    Nagy, A; Vandersmissen, E; Kapp, P


    Out of a total of 224 bovine eye secretions, 126 Moraxella bovis and 64 Neisseria ovis strains were isolated. The pathogenesis and histological lesions caused by Neisseria ovis have been studied on the eyes of three calves naturally affected with IBK, using electron microscopy. Neisseria ovis caused in 1-12 weeks old calves acute, transient and mostly benign serous conjunctivitis with only slight affection of the cornea. More rarely erosions and even ulceration of the cornea have been observed. Moraxella bovis and Neisseria ovis strains proved nearly unanimously sensitive in vitro to chloramphenicol, neomycin, oxytetracyclin, nitrofurantoin, erythromycin and cefoperazone. Other antibiotics and chemotherapeutics inhibited the growth of these agents only partly or were ineffective. Experimental therapy has been carried out using a single i.m. injection of Terramycin/LA inj. (Pfizer) in a dose of 20 mg/kg body mass, repeated if necessary after 72-96 h. This formulation proved more effective and practical than treatments used earlier.

  5. Treatment of bovine dermatophilosis with Senna alata, Lantana camara and Mitracarpus scaber leaf extracts. (United States)

    Ali-Emmanuel, N; Moudachirou, M; Akakpo, J A; Quetin-Leclercq, J


    This study describes interesting preliminary results on the therapeutic effects of ointments prepared with extracts of medicinal plants on bovine dermatophilosis. Our results show that the use of ointments made with ethanolic extracts of leaves of Senna alata, Lantana camara and Mitracarpus scaber, as topical treatments on chronic crusty or acute lesions of dermatophilosis, induces healing of the disease in the nine infected animals treated without recurrence. This is opposed to what is observed by using oxytetracycline, terramycin long-acting (TLA), or procaine-penicillin, antibiotics commonly used parenterally for the treatment of dermatophilosis in the Republic of Benin which could not prevent the recurrence of the disease. These ointments, when applied once a day for 8-15 days, provoked the falling off of the crusts after 3-4 days of treatment. Hair grows on the treated areas, which heal without scarring, within 3-4 weeks after the end of the treatment. The healed animals became free of dermatophilosis without recurrence for more than 3 years and were in good health.

  6. In vitro study of the antimicrobial activity of Brazilian propolis against Paenibacillus larvae. (United States)

    Bastos, Esther Margarida A F; Simone, Michael; Jorge, Daniela Macedo; Soares, Ademilson Espencer Egea; Spivak, Marla


    The honey bee disease American foulbrood (AFB) is a serious problem since its causative agent (Paenibacillus larvae) has become increasingly resistant to conventional antibiotics. The objective of this study was to investigate the in vitro activity of propolis collected from various states of Brazil against P. larvae. Propolis is derived from plant resins collected by honey bees (Apis mellifera) and is globally known for its antimicrobial properties and particularly valued in tropical regions. Tests on the activity of propolis against P. larvae were conducted both in Brazil and Minnesota, USA using two resistance assay methods that measured zones of growth inhibition due to treatment exposure. The propolis extracts from the various states of Brazil showed significant inhibition of P. larvae. Clear dose responses were found for individual propolis extracts, particularly between the concentrations of 1.7 and 0.12 mg propolis/treatment disk, but the source of the propolis, rather than the concentration, may be more influential in determining overall activity. Two of the three tested antibiotics (tylosin and terramycin) exhibited a greater level of inhibition compared to most of the Brazilian samples, which could be due to the low concentrations of active compounds present in the propolis extracts. Additionally, the majority of the Brazilian propolis samples were more effective than the few collected in MN, USA. Due to the evolution of resistance of P. larvae to conventional antibiotic treatments, this research is an important first step in identifying possible new active compounds to treat AFB in honey bee colonies.

  7. 'Pink eye' or 'zere oogjes' or keratoconjunctivitis infectiosa ovis (KIO). Clinical efficacy of a number of antimicrobial therapies. (United States)

    König, C D


    In a comparative study the clinical efficacy of five different treatments of keratoconjunctivitis infectiosa ovis (KIO) were tested, namely an intramuscular injection of chloramphenicol base (dosage 15 mg/kg), spiramycin base (Suanovil dosages 10 to 25 mg/kg), oxytetracycline (Engemycine Forte, Terramycin LA, dosages respectively 5 and 10 mg/kg), tiamulin (Dynamutulin, dosage 10 mg/kg) and subcutaneous injection of procaine penicillin G, benzathine penicillin G. and dihydrostreptomycin in the lower eyelid. It appeared from these field trials that spiramycin base, oxytetracycline and tiamulin had a clearly positive effect on the clinical course of 'pink eye', although with tiamulin there was only a temporary effect (high percentage of relapses). In view of the field data the following dosage schemes are, for the time being, advised: spiramycin base (Suanovil), and oxytetracycline (formulation with a good biological availability) both 20 to 30 mg/kg and, if necessary, to be repeated on days 5 and 10 after the first intramuscular injection. The dosage scheme advised for tiamulin is 20-30 mg/kg to be repeated on day 3 and if necessary on days 6 and 9 after the intramuscular injection. In mild cases it is sufficient to rub the eyes with for example oxytetracycline eye-ointment, a few times a day.

  8. Clinical management of stage I pinkeye with concurrent pneumonic pasteurellosis in a goat: A case report

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    Faez Firdaus Abdullah Jesse


    Full Text Available Objective: This clinical case reports the occurrence of stage I pinkeye with concurrent pneumonic pasteurellosis in a goat. Materials and methods: A 2-year-old Jamnapari goat weighing 25 Kg was presented to the Universiti Veterinary Hospital, Universiti Putra Malaysia with primary complain of eye problem and inappetence. Results: Upon clinical examination, the most prominent abnormality observed was corneal opacity of the right eye with presence of ulceration on the corneal surface and chemosis of the right conjunctiva with excessive lacrimation. On auscultation, there was the presence of crackle lung sounds with bilateral mucopurulent nasal discharges. Samples from the ocular swab yielded a positive growth for Mycoplasma spp., while the nasal swab yielded a positive growth for Mannheimia haemolytica. The goat was diagnosed with stage I pinkeye with concurrent pneumonic pasteurellosis infection. Treatment was instituted with 400 mL of 0.9% NaCl administered intravenously once for rehydration. Flunixin meglumine 2.2 mg/kg bwt was given intramuscularly twice daily for three days as anti-inflammatory and analgesic. Oxytetracycline 20 mg/kg bwt was injected once intramuscularly as long acting broad spectrum antibiotic for treatment of pinkeye and pasteurellosis infections. Furthermore, terramycin eye ointment containing oxytetracycline HCl was also administered intraocularly twice daily for seven days as treatment for the Mycoplasma spp. Conclusion: The prognosis for this case was good as the goat were treated promptly and effectively. [J Adv Vet Anim Res 2017; 4(4.000: 390-393

  9. In vitro and in vivo protocols of antimicrobial bioassay of medicinal herbal extracts: A review

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    Najeeb Ullah


    Full Text Available Antimicrobial susceptibility testing against pathogenic microorganisms is the most significant task of clinical microbiology laboratory. The present study was therefore designed to review the in vitro and in vivo protocols of antimicrobial bioassays of various medicinal herbal extracts against a diversity of pathogenic microorganisms. Plants have a broad variety of antimicrobial agents which are extensively used as herbal drugs against different microbes. The review covers the antimicrobial techniques and antimicrobial bioassays of medicinal herbal extracts against different bacterial and fungal strains from 2000 onward. Plants have diverse concentrations of bioactive constituents such as alkaloids, saponins, tannins, terpenoids, steroids, carbohydrates, proteins and lipids. These phytochemicals are used against an extensive range of bacteria (Escherichia coli, Mycobacterium, Corynebacterium pervum, Bordetella pertusis, Klebsiella pneumoniae, Salmonella typhi, viruses (simian-virus, retrovirus and fungi (Pseudomonas aeruginosa, Aspergillus fumigatus, Aspergillus flavus, Fusarium solani. A variety of antibiotics (tetracycline, terramycin, ampicillin has also been isolated from different medicinal plants. This review was therefore intended to explore the techniques used for antimicrobial activities of herbal medicinal extracts.

  10. Oxidative Stability and Physico-chemical Properties of Meat from Broilers Fed with Dietary Neem Leaf Powder, Spirulina and their Combination

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    Ravi KILLI


    Full Text Available This 6 week study was conducted to evaluate the antioxidant potential, maintaining quality and sensory properties of broiler meat from birds fed on dietary neem leaf powder (NLP. A total of 90 Vencobb broiler chicks were randomly allotted to 6 groups of 15 birds in each. Dietary treatments consisted of normal diet (control Group I, feed containing terramycin-200 (TM-200* at the concentration of 0.05% (Group II, feed containing NLP of 0.2% (Group III, feed containing NLP of 0.2% and spirulina of 1% (Group IV, feed containing TM-200 at 0.05% and spirulina of 1% (Group V and feed containing spirulina of 1% (Group VI. At the end of the experiment liver, kidney and muscle samples were collected to evaluate the tissue peroxidation (TBARS and protein carbonyls and antioxidant markers (SOD. Physico-chemical quality determinants of both fresh and preserved meat viz. extract release volume (ERV, water holding capacity (WHC and pH were also studied. TBARS protein carbonyls indicated a significant (P < 0.05 decrease in all the treated groups when compared to control. Superoxide dismutase levels were found to be significantly increased in all the treated groups, in all the tissues collected. Compared to control group, favorable physico-chemical quality determinants were recorded in all the treated groups. The sensory attributes did not show significant (P < 0.05 differences for color, flavor, juiciness, tenderness and overall acceptability. This study indicates enhanced stress tolerance levels, improved meat quality with unaffected consumer acceptance levels of the meat observed in the study, from broilers fed with neem and spirulina either alone or in combinationsș this points out that neem at 0.2% level can be used in poultry diets instead of antibiotic growth promoters (AGP.