Bakkebø, Tina; Widnes, Sofia Frost; Aamlid, Synnøve Stubmo; Schjøtt, Jan
Clinical decision support provided by drug information centers is an intervention that can ensure rational drug therapy for pregnant women. We have examined whether physicians' teratogenic risk perceptions and confidence in prescribing drugs to pregnant women is altered after advice from the Norwegian drug information centers, Regional Medicines and Pharmacovigilance Centres i Norway (RELIS). Physicians who consulted RELIS for advice on patient-specific drug use in pregnancy from November 2013 to April 2014 completed questionnaires before and after receiving the advice. A scale from 1 to 7 was used to rate confidence in prescribing and perception of teratogenic risk. The lower part of the scale represented a low perception of teratogenic risk and a high confidence in prescribing a drug in pregnancy. The data were analyzed using a mixed linear model. A total of 45 physicians participated in the study and they assessed 64 drugs or categories of drugs. Advice from RELIS increased confidence in prescribing, with a statistically significant mean change on the scale from 4.1 to 2.9. The assessment of teratogenic risk was reduced after advice from RELIS, with a mean change from 3.2 to 2.5, though this was not significant. A subgroup of 26 physicians completed questionnaires both before and after advice from RELIS and assessed a total of 32 drugs or categories of drugs. In 94% of these assessments, advice from RELIS altered the physician's confidence in prescribing. Perception of teratogenic risk was altered in 78% of the assessments. Our results show that physicians' perception of teratogenic risk and confidence in prescribing drugs to pregnant women is influenced by advice from Norwegian drug information centers. Copyright © 2016 Elsevier HS Journals, Inc. All rights reserved.
Newspaper librarians discussed the public use of their newspapers' libraries. Policies run the gamut from well-staffed public information services, within or outside the newspaper library, to no service at all to those outside the staff of the paper. Problems of dealing with tax and law enforcement agencies were covered, as well as cooperative…
Full Text Available Vera Ehrenstein1, Henrik T Sørensen1, Leiv S Bakketeig1,2, Lars Pedersen11Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark; 2Norwegian Institute of Public Health, Oslo, NorwayAbstract: More than half of all pregnant women take prescription medications, raising concerns about fetal safety. Medical databases routinely collecting data from large populations are potentially valuable resources for cohort studies addressing teratogenicity of drugs. These include electronic medical records, administrative databases, population health registries, and teratogenicity information services. Medical databases allow estimation of prevalences of birth defects with enhanced precision, but systematic error remains a potentially serious problem. In this review, we first provide a brief description of types of North American and European medical databases suitable for studying teratogenicity of drugs and then discuss manifestation of systematic errors in teratogenicity studies based on such databases. Selection bias stems primarily from the inability to ascertain all reproductive outcomes. Information bias (misclassification may be caused by paucity of recorded clinical details or incomplete documentation of medication use. Confounding, particularly confounding by indication, can rarely be ruled out. Bias that either masks teratogenicity or creates false appearance thereof, may have adverse consequences for the health of the child and the mother. Biases should be quantified and their potential impact on the study results should be assessed. Both theory and software are available for such estimation. Provided that methodological problems are understood and effectively handled, computerized medical databases are a valuable source of data for studies of teratogenicity of drugs.Keywords: databases, birth defects, epidemiologic methods, pharmacoepidemiology
Kaplan, Yusuf Cem; Karadaş, Barış; Küçüksolak, Gözde; Ediz, Bartu; Demir, Ömer; Sozmen, Kaan; Nordeng, Hedvig
Background Previous studies from western countries demonstrated the effectiveness of Teratology Information Service (TIS) counselling in reducing the teratogenic risk perception of pregnant women. Objective To assess whether TIS counselling would be effective in reducing the teratogenic risk perception of the Turkish pregnant women. Setting A TIS (Terafar) operating in a university hospital in Turkey. Methods A cross-sectional survey study. Pregnant women with non-teratogenic medication exposures were asked to assign scores on visual analogue scales (VAS) in response to the questions aiming to measure their teratogenic risk perception. The mean score before and after counselling were compared and the associations with maternal socio-demographic characteristics were analysed using SPSS (Version 20.0). Main outcome measures The differences in the mean scores of the perception regarding the baseline risk of pregnancy, own teratogenic risk and the likelihood of termination of pregnancy before and after counselling and their possible associations with maternal socio-demographic characteristics. Results 102 pregnant women participated in the study. The counselling significantly reduced the mean own teratogenic risk perception score and the mean score for the likelihood of termination of pregnancy whereas the mean baseline risk perception score was not significantly changed. Pregnancy week <8 and the exposed number of active ingredients <3 were significantly associated with the difference in the mean score for the likelihood of termination of pregnancy. Conclusions TIS counselling lowers the teratogenic risk perception of Turkish pregnant women and increases their likelihood to continue the pregnancy as it does in the western countries.
The Information Services Directory is intended to facilitate participation by states, affected Indian tribes and the public in the Civilian Radioactive Waste Management Program. The Directory is produced by the Information Services Division of the OCRWM's Office of Policy and Outreach and will be updated periodically. It is a reference document that identifies the sources of available program information
The Information Services directory is intended to facilitate participation by states, affected Indian tribes and the public in the Civilian Radioactive Waste Management program. The Directory is produced by the Information Services Division of the OCRWM's Office of Policy and Outreach and will be updated periodically. It is a reference document that identifies the sources of available program information
Attempts made to design and extend space system capabilities are reported. Special attention was given to establishing user needs for information or services which might be provided by space systems. Data given do not attempt to detail scientific, technical, or economic bases for the needs expressed by the users.
Hancock, Rebecca L; Ungar, Wendy J; Einarson, Adrienne; Koren, Gideon
Teratology Information Services (TIS) provide health care professionals and the public with information regarding the safety and/or risk of exposures during pregnancy and lactation, mainly via telephone consultations. An international comparison of clinical practices at TIS has never been conducted. The survey objective was to compare international TIS to North American TIS, with an aim to identify strengths and challenges that can lead to service improvement. Twenty-two international TIS were approached for participation during an international conference. TIS were surveyed on information in six categories: services, staffing, operations, data collection, knowledge transfer activities and additional information. Data were summarized using descriptive statistics. Statistical tests were conducted using SPSS®. Sixteen TIS from 12 countries participated. Survey results were compared with previously reported results from a similar survey of North American TIS (16 US, two Canadian). TIS exist in a variety of departments and settings, but most commonly are in university hospitals. Pregnant women were the most commonly counselled group worldwide. International TIS spent significantly more time fielding inquiries regarding medications, while North American TIS had a wider variety of inquiry categories. All TIS could improve budget tracking. Overall, service practices and goals were similar, although international TIS conducted more follow-up with service users than North American TIS. This report offers TIS the first ever opportunity to compare practices. Increased dialogue between TIS encourages sharing of best practices and improves the ability of these important public health programmes to support women and health care providers. © 2010 Blackwell Publishing Ltd.
Ageron, M.; Boninchi, V.; Chartoire, M.; Combroux, A.; Giraud, N.; Jacquet, G.; Lagrange, B.; Malleret, S.; Martin, C.; Mas, J.; Morgue, M.; Ollivier, T.
The information technology service works out the choices concerning the information technology systems of general use in the laboratory: computers, network, peripherals, workstations, software. It intervenes at the same time in the definition of the procedures and equipment specific to the research groups. The entire data acquisition is centralized by the service. The personnel is sharing the following two large directions of activities: - management of information technology park (setup, configuration and maintenance of the materials and soft ensemble, training and assistance afforded to users); - participation in software projects either in elaboration of applications or in realization and maintenance of specific tools
The Medical Service is pleased to inform you that a psychologist specialising in psychotherapy (member of the Swiss Federation of Psychologists- FSP), Mrs Sigrid Malandain, will be starting work at the CERN on 1 November 2010, in the premises of the Medical Service, Building 57-1-024. Members of CERN personnel can request individual consultations, by appointment, in French or in English, on Tuesdays and Thursdays by calling 78435 (Medical Service secretariat) or sending an e-mail to email@example.com.
BNF is the UK nuclear industry's representative organisation and its membership is inclusive of the entire civil nuclear industry in the Britain. BNF members include Britain's two nuclear electricity generating companies, Nuclear Electric and Scottish Nuclear, who between them manage the seventeen nuclear power stations which provide approximately 20% of the country's generating capacity. An important role of the Forum is to act as the information centre for the industry as a whole and during 1992, the Forum has strengthened its information service with the setting up of an extensive, computer-based network. The network has been established to provide an effective way of managing UK domestic nuclear-related issues and for maximising the news value of our industry's achievements. Equally important is the service's role as an international source of information - particularly when nuclear incidents occur outside the UK. The Forum also acts as an international exchange centre, disseminating technical information, for example, and by promptly providing accurate and comprehensive information to minimise the potential damage to public confidence in nuclear power generation which may be caused by any reported nuclear incidents. Recent examples of the successful operation of the BNF information service and its communications network have been the Leningradskya incident in March 1992 and the hurricane Andrew situation which developed at the end of August 1992
Stancil, Stephani L; Miller, Melissa; Briggs, Holley; Lynch, Daryl; Goggin, Kathy; Kearns, Gregory
Rates of adult women receiving contraceptive provision when simultaneously prescribed a known teratogen are alarmingly low. The prevalence of this behavior among pediatric providers and their adolescent patients is unknown. The objective of this study was to describe pediatric provider behaviors for prescribing teratogens concurrently with counseling, referral, and/or prescribing of contraception (collectively called contraceptive provision) in the adolescent population. A retrospective review was conducted examining visits in 2008-2012 by adolescents aged 14 to 25 years in which a known teratogen (US Food and Drug Administration pregnancy risk category D or X) was prescribed. The electronic medical records were queried for demographic information, evidence of contraceptive provision, and menstrual and sexual histories. The data were analyzed using standard statistical methods. Within 4172 clinic visits, 1694 females received 4506 prescriptions for teratogenic medications. The most commonly prescribed teratogens were topiramate, methotrexate, diazepam, isotretinoin, and enalapril. The subspecialties prescribing teratogens most frequently were neurology, hematology-oncology, and dermatology. Overall, contraceptive provision was documented in 28.6% of the visits. Whites versus nonwhites and older versus younger girls were more likely to receive contraceptive provision. The presence of a federal risk mitigation system for the teratogen also increased the likelihood of contraceptive provision. Our data demonstrate female adolescents prescribed teratogens receive inadequate contraception provision, which could increase their risk for negative pregnancy outcomes. Although the presence of a federal risk mitigation system appears to improve contraceptive provision, these systems are costly and, in some instances, difficult to implement. Efforts to improve provider practices are needed. Copyright © 2016 by the American Academy of Pediatrics.
Congress passed the Nuclear Waste Policy Act of 1982 (NWPA) and its amendments establishing the National policy for safely storing, transporting and disposing of spent nuclear fuel and high-level radioactive waste in a geologic repository. This legislation created the Office of Civilian Radioactive Waste Management (OCRWM) within the US Department of Energy (DOE) to develop an integrated system for the safe and efficient disposal of high-level radioactive waste. The NWPA, as amended, directs DOE to study in detail the Yucca Mountain site in Nevada as the only candidate site for the Nation's geologic repository. In Nevada, the DOE/OCRWM Yucca Mountain Site Characterization Project Office (YMPO) manages scientific investigations to determine the suitability of Yucca Mountain for effectively isolating radioactive waste from the public and the environment. This Information Services Directory is intended to facilitate dissemination of information. The Directory is produced by the Education and Information Division of OCRWM's Office of External Relations and will be updated periodically. This is the third such update since its issuance in August 1986. It is a reference document that lists the sources of program information available to States, Indian Tribes and the public
PROF. O. E. OSUAGWU
Dec 1, 2013 ... Information Services (IIS) packages have been presented. Note that while some of ... encompasses a variety of services including FTP, SMTP ..... for Web-based Distributed Authoring ... denial-of-service vulnerabilities we have.
Lo, W Y; Friedman, J M
To determine how long it takes after a new drug is marketed to establish whether or not its use by pregnant women is likely to pose a substantial teratogenic risk. We used standard clinical teratology resources to assess the teratogenic risks in human pregnancy of therapeutic treatment with 468 drugs approved by the US Food and Drug Administration between 1980 and 2000. The teratogenic risk of each treatment was classified using the current online version of TERIS into one of three categories: 1) no risk, minimal risk, or unlikely to produce an increased risk; 2) associated with a small, moderate, or high risk; or 3) risk undetermined. We found that the teratogenic risk in human pregnancy was still undetermined for 91.2% of drug treatments approved in the United States between 1980 and 2000. The proportion of treatments classified as having an "undetermined" teratogenic risk was more than 80% for drugs approved for marketing 0-4, 5-9, 10-14, or 15-20 years ago, but the highest proportion of drugs with an "undetermined" teratogenic risk was found among those approved 15-20 years ago. The agreement between TERIS risk ratings and Food and Drug Administration Use-in-Pregnancy Categories for 163 drugs that had been assessed by both systems was poor (kappa +/- standard error = 0.082 +/- 0.042). We conclude that inadequate information is available for pregnant women and their physicians to determine whether the benefits exceed the teratogenic risks for most drug treatments introduced in the past 20 years.
De Santis, Marco; Cesari, Elena; Cavaliere, Annafranca; Ligato, Maria Serena; Nobili, Elena; Visconti, Daniela; Caruso, Alessandro
We describe paternal exposure and counselling in a selected population calling to an Italian Teratology Information Service (TIS). The majority of callers asked for paternal drug exposure (76%, drugs except chemotherapy) and treatment for cancer (17%, chemotherapy and/or radiotherapy). Others asked for exposure to diagnostic radiations (4%), recreational drugs (2%) and occupational chemicals (1%). Among paternal drugs neurological compounds, immunosuppressive drugs and antiviral agents were the main reasons for calling. In humans, there are no evidences of birth defects after paternal exposures, but to minimize any possible risk, counselling in men exposed to radio and chemotherapy should recommend delaying conception for at least 3 months after the end of the therapy. Male patients treated with drugs, whose teratogenic potential has been well assessed or suspected for maternal exposure, should be advised to practice effective birth control during therapy and up to one or two cycles of spermatogenesis and to avoid semen contact with vaginal walls during first trimester of pregnancy.
Full Text Available Congenital malformations are still the important medical and social issue. They take the second place among the reasons for the infant mortality and cause up to 18,3% of disablement cases among the children. Exogenous factors, effecting the growing fetus, are very essential along with the genetic matters among the reasons for the congenital malformations. The importance of information on the teratogenic potential of the medications is acknowledged by the doctors from various countries. The article outlines the information on entis activity — European network of teratology information services — a non profit organization, rendering consulting services to the pregnant women and medical staff, regarding the embryo and fetotoxic actions of the medications. The authors highlight the history of entis, its objectives, principles of operation and consulting algorithm and list the basic scientific publications by the entis members for the recent years. The article deals with the most obvious problems, which the organization members face, first of all — the quality of the information they receive. The authors also provide the substantiation for the necessity to develop such an information service in Russia and express hope for the successful development of the entis subsidiary they formed in Moscow.Key words: congenital malformations, medications, pregnancy, embryotoxicity.
Casanova Sorní, C; Romá Sánchez, E; Pelufo Pellicer, A; Poveda Andrés, J L
To assess the teratogenic risk associated with leflunomide during the first quarter of pregnancy, and to establish guidelines to minimize said risk. Literature search using tertiary, secondary, and primary sources related to teratogenicity, including databases (MEDLINE and EMBASE) and specific webs. The information required for assessment, as well as for the establishment of criteria was collected. Leflunomide demonstrated an increased risk of fetal death and teratogenic effects in animals. No major or minor malformation cases have been reported in humans regarding leflunomide, which is classified within category X of fetal risk. A wash-out regimen may possibly reduce the risk for fetal harm. Conception scheduling or early pregnancy detection is required for better clinical counselling and the avoidance of unnecessary risk.
Maria Helena de Castro Chagas
Full Text Available A vitamina A é essencial à preservação e ao funcionamento normal dos tecidos, assim como, ao crescimento e desenvolvimento. No humano há evidência indireta que a vitamina A em excesso, durante as primeiras semanas de gestação é teratogênica. Do contrário, não há dúvidas sobre os efeitos deletérios, de uma alimentação carente neste micronutriente e sobre a disponibilidade do conhecimento técnico para evitá-los. A preocupação com o fato de que a vitamina A conduziria a teratogenia em humanos, tem retardado a implementação de programas de combate a carência de vitamina A, atingindo principalmente os programas de enriquecimento de alimentos. A literatura é controvertida e dispõe de poucas informações sobre as doses para suplementação de gestantes. Como o retinol circulante materno é controlado homeostaticamente após o consumo de alimentos fonte de vitamina A, espera-se a mesma resposta metabólica após o consumo de alimentos fortificados, indicando que não há risco de teratogenia. Consequentemente, parece altamente improvável que o consumo de alimentos enriquecidos ou de suplementos de vitamina A pré-formada, nas doses unitárias habituais, tenha efeito teratogênico no homem.The vitamin A is essential to the preservation and the normal functioning of tissues, as well as, to the growth and development. In the human being it has indirect evidence that the vitamin A in excess, during the first weeks of gestation is teratogenic. Of the opposite, it does not have doubts on the deleterious effect, of a devoid feeding in this micronutrient and on the availability of the knowledge technician to prevent them. The concern with the fact of that the vitamin A would lead it the teratogenicity in human beings, has delayed the implementation of combat programs the vitamin A lack, mainly reaching the programs of food enrichment. Literature is controverted and makes use of few information on the doses for supplementation of
This Directory will facilitate dissemination of information. It is a reference document that lists the sources of program information available to the states, Indian Tribes, and the public. Chapter 1 describes current program information sources produced by OCRWM and by DOE's Office of Scientific and Technical Information (OSTI). Chapter 2 provides a directory of OCRWM and DOE technical information, and includes descriptions of computerized data bases and other resources. Chapter 3 is an index of OCRWM Headquarters and Project Office contacts, as well as state and Indian Tribe contacts. Chapter 4 enumerates Congressional Committees and Subcommittees that have jurisdiction over various components of the Civilian Radioactive Waste Management Program, and Chapter 5 lists DOE reading rooms, as well as information offices and the public libraries in affected states that are on one or more of OCRWM's mailing lists
Discusses the advantages and limitations of market segmentation as strategy for the marketing of information services made available by nonprofit organizations, particularly libraries. Market segmentation is defined, a market grid for libraries is described, and the segmentation of information services is outlined. A 16-item reference list is…
Haro, A. S.
Discusses the need to apply modern scientific management to health administration in order to effectively manage programs utilizing increased preventive and curative capabilities. The value of having maximum information in order to make decisions, and problems of determining information content are reviewed. For journal availability, see SO 506…
This essential overview of what it means to be a library and information professional today provides a broad overview of the transformation of libraries as information organizations, why these organizations are more important today than ever before, the technological influence on how we provide information resources and services in today's digital and global environment, and the various career opportunities available for information professionals. The book begins with a historical overview of libraries and their transformation as information and technology
Department of Veterans Affairs — This service is used to create, read, delete and update additional information captured during the EVSS Disability Compensation interview in an effort to align with...
Perez-Aytes, Antonio; Marin-Reina, Purificacion; Boso, Virginia; Ledo, Ana; Carey, John C; Vento, Maximo
Mycophenolate mofetil (MMF) is probably the most common employed immunosuppressant drug in recipients of solid organ transplant and in many autoimmune diseases. In vitro studies, a significant number of single clinical observations and a recent study from a group of different European teratogen information services, have provided very consistent data supporting the existence of a specific MMF embryopathy. The typical malformative pattern of MMF embryopathy includes external ear anomalies ranging from hypoplastic pinna (microtia) to complete absence of pinna (anotia); cleft lip, with or without cleft palate, and ocular anomalies as iris or chorioretinal coloboma and anophthalmia/microphthalmia. Other less frequent features are congenital heart defects, distal limbs anomalies, esophageal atresia, vertebral malformations, diaphragmatic hernia, and kidney and central nervous system anomalies. Neurodevelopmental outcome seems favorable in the small number of patients where information about this issue is available, but neurological deficits have been documented. Physicians in charge of women under MMF therapy should be aware of the potential risk of this drug to cause a specific embryopathy and the need of interrupting the treatment at least six weeks before becoming pregnant. Copyright © 2016 Elsevier Masson SAS. All rights reserved.
Internet Technologies and Information Services: Second Edition is a vital asset to students preparing for careers in library and information science and provides expanded coverage to important new developments while still covering Internet foundations. In addition to networking, the Internet, HTML, web design, web programming, XML, and web searching, this new edition covers additional topics such as cloud computing, content management systems, eBook technologies, mobile technologies and applications, relational database management systems (RDMS), open source software, and virtual priva
Dissemination of information is an essential part of CERN's mission. It brings people together from all around the world and trains the scientists of tomorrow. CERN scientific output is documented and made available for the scientific community and the general public through the CERN Document Server, INSPIRE-HEP and Wikipedia. This report presents the work done in the Scientific Information Service during the summer student program.
Ferreira Pires, Luis; Wang, J.; van Oostrum, Arjen; Wijnhoven, Alphonsus B.J.M.
A service registry is a Service-Oriented Architecture (SOA) component that keeps a ‘catalogue’ of available services. It stores service specifications so that these specifications can be found by potential users. Discussions on the design of service registries currently focus on technical issues,
Cavallini, J.S.; Aiken, R.J.
The Government Services Information Infrastructure (GSII) is that portion of the NII used to link Government and its services, enables virtual agency concepts, protects privacy, and supports emergency preparedness needs. The GSII is comprised of the supporting telecommunications technologies, network and information services infrastructure and the applications that use these. The GSII is an enlightened attempt by the Clinton/Gore Administration to form a virtual government crossing agency boundaries to interoperate more closely with industry and with the public to greatly improve the delivery of government services. The GSII and other private sector efforts, will have a significant impact on the design, development, and deployment of the NII, even if only through the procurement of such services. The Federal Government must adopt new mechanisms and new paradigms for the management of the GSII, including improved acquisition and operation of GSII components in order to maximize benefits. Government requirements and applications will continue to evolv. The requirements from government services and users of form affinity groups that more accurately and effectively define these common requirements, that drive the adoption and use of industry standards, and that provide a significant technology marketplace.
CERN Staff and Users can now consult their dose records for an individual or an organizational unit with HRT. Please see more information on our web page: http://cern.ch/rp-dosimetry. The Dosimetry Service is open every morning from 8.30 to 12.00 and is closed in the afternoons. We would like to remind you that dosimeters cannot be sent to customers by internal mail. Short-term dosimeters (VCT's) must always be returned to the Service after use and must not be left on the racks in the experimental areas or in the secretariats.
CERN Staff and Users can now consult their dose records for an individual or an organizational unit with HRT. Please see more information on our web page http://cern.ch/rp-dosimetry. The Dosimetry Service is open every morning from 8.30 - 12.00, and closed in the afternoons. We would like to remind you that dosimeters cannot be sent to customers by internal mail. Short-term dosimeters (VCT's) must always be returned to the Service after use and must not be left on the racks in the experimental areas or in the secretariats.
The Hungarian National Association of Radio Distress-Signalling and Infocommunications (RSOE) operates Emergency and Disaster Information Service (EDIS) within the frame of its own website which has the objective to monitor and document all the events on the Earth which may cause disaster or emergency. Our service is using the speed and the data spectrum of the internet to gather information. We are monitoring and processing several foreign organisation's data to get quick and certified information. The EDIS website operated together by the General-Directorate of National Disaster Management (OKF) and RSOE, in co-operation with the Crisis Management Centre of the Ministry of Foreign Affairs, provides useful information regarding emergency situations and their prevention. Extraordinary events happening in Hungary, Europe and other areas of the World are being monitored in 24 hours per day. All events processed by RSOE EDIS are displayed real time - for the sake of international compatibility - according to the CAP protocol on a secure website. To ensure clear transparency all events are categorized separately in the RSS directory (e.g. earthquake, fire, flood, landslide, nuclear event, tornado, vulcano). RSOE EDIS also contributes in dissemination of the CAP protocol in Hungary. Beside the official information, with the help of special programs nearly 900-1000 internet press publication will be monitored and the publication containing predefined keywords will be processed. However, these "news" cannot be considered as official and reliable information, but many times we have learnt critical information from the internet press. We are screening the incoming information and storing in a central database sorted by category. After processing the information we are sending it immediately via E-Mail (or other format) for the organisations and persons who have requested it (e.g. National Disaster Management, United Nations etc.). We are aspiring that the processed data
Bentur, Y.; Horlatsch, N.; Koren, G.
We quantified the perception of teratogenic risk in women attending the Motherisk program for counseling about diagnostic radiation in pregnancy (n = 50) and compared it with a control group of women exposed to nonteratogenic drugs and chemicals (n = 48). Before receiving known information about the specific exposure, women exposed to radiation assigned themselves a significantly higher teratogenic risk compared with the control group (25.5 +/- 4.3% versus 15.7 +/- 3.0% for major malformations, P less than 0.01). The post-consultation perception of teratogenic risk did not differ between the two groups. Special consideration and attention should be given when counseling pregnant women exposed to low-dose ionizing radiation, as their misperception of teratogenic risk may lead them to unnecessary termination of their pregnancy
Green, Benedict T; Lee, Stephen T; Panter, Kip E; Brown, David R
Piperidine alkaloids are acutely toxic to adult livestock species and produce musculoskeletal deformities in neonatal animals. These teratogenic effects include multiple congenital contracture (MCC) deformities and cleft palate in cattle, pigs, sheep, and goats. Poisonous plants containing teratogenic piperidine alkaloids include poison hemlock (Conium maculatum), lupine (Lupinus spp.), and tobacco (Nicotiana tabacum) [including wild tree tobacco (Nicotiana glauca)]. There is abundant epidemiological evidence in humans that link maternal tobacco use with a high incidence of oral clefting in newborns; this association may be partly attributable to the presence of piperidine alkaloids in tobacco products. In this review, we summarize the evidence for piperidine alkaloids that act as teratogens in livestock, piperidine alkaloid structure-activity relationships and their potential implications for human health. Copyright © 2012 Elsevier Ltd. All rights reserved.
Manager Information Management and Innovation Services ... manages research services for end users, ensures that internal clients know how to access ... in order to ensure that services provided meet a high level of quality and client needs ...
Ito, Takumi; Ando, Hideki; Handa, Hiroshi
Half a century ago, thalidomide was developed as a sedative drug and was wildly used over 40 countries. However the drug has serious birth defects such as amelia and phocomelia. Now thalidomide is regarded as a clinically effective drug and used for the treatment of multiple myeloma under strict controls. The direct target of thalidomide had been a long-standing question. We identified cereblon as a primary direct target protein for thalidomide teratogenicity using new affinity bead technology in 2010. In this review, we introduce an overview of thalidomide teratogenicity, a story about how we identified cereblon, and recent advances in cereblon studies.
Palazov, Atanas; Stefanov, Asen
The ultimate goal of modern oceanography is an end user oriented product. Beneficiaries are the governmental services, coast-based enterprises and research institutions that make use of the products generated by operational oceanography. Direct potential users and customers are coastal managers, shipping, offshore industry, ports and harbours, fishing, tourism and recreation industry, and scientific community. Indirect beneficiaries, through climate forecasting based on ocean observations, are food, energy, water and medical suppliers. Five general classes of users for data and information are specified: (1) operational users that analyze the collected data and produce different forecasts serving to impose regulation measures; (2) authorities and managers of large-scale projects needing timely oceanographic information, including statistics and climatic trends; (3) industrial enterprises, safety of structures and avoiding of pollution; (4) tourism and recreation related users aiming protection of human health; (5) scientists, engineers, and economists carrying out special researches, strategic design studies, and other investigations to advance the application of marine data. The analysis of information received during the extensive inquiry among all potential end users reveals variety of data and information needs encompassing physical, chemical, biological and hydrometeorological observation. Nevertheless, the common requirement concerns development of observing and forecasting systems providing accurate real-time or near-real time data and information supporting decision making and environmental management. Availability of updated information on the actual state as well as forecast for the future changes of marine environment are essential for the success and safety of maritime operations in the offshore industry. For this purpose different systems have been developed to collect data and to produce forecasts on the state of the marine environment and to provide
Jun Luo; Weiguo Zhang.; Dabin Qin
It is important to retain customer satisfaction in information technology services. When a service failure occurs, companies need to take service recovery action to recover their customer satisfaction. Although companies cannot avoid all problems and complaints, they should try to make up. Therefore, service failure and service recovery have become an important and challenging issue for companies. In this paper, the literature and the problems in the information technolog...
Please note the following opening hours of the Service: From 31st July onwards: Every morning from 8:30 to 12:00 The Service is closed in the afternoons. We should like to remind you that dosimeters cannot be sent to customers by internal mail. Short-term dosimeters (VCTs) must always be returned to the Service after use and must not be left on the racks in the experimental areas or in the secretariats. Dosimetry Service Tel 72155 Bldg. 24 E 011 Dosimetry.firstname.lastname@example.org http://cern.ch/rp-dosimetry
The University of Calgary was the first university in Canada to combine its library, computer center, and audiovisual services into one unit. For a period of three years the Division of Information Services administered and coordinated library services, computer services, and communications media. The organizational structure, objectives, and the…
Discusses serving library-patron needs in terms of customer service and quality control. Highlights include tools for measuring the quality of service (e.g., the SERVQUAL survey), advisory boards or focus groups, library "service statements," changing patron needs, new information formats, and justifying depository library services. (JAK)
Please note that the Registration Service (Bldg 55-1st floor) will be exceptionally open during the annual end of year closure from 10:00 to 12:00 on the following days: 22, 23, 26, 27,28, 29 et 30 December 2011 and 2,3, et 4 January 2012. All the activities related to the Registration Service will be operational: registration for contractors’ personnel; registrations for professional visits; access cards; car stickers; biometric registration. The Registration Service
Please note the following opening hours of the Service: In June: Every morning from 8:30 to 12:00 In July: Mondays, Wednesdays and Fridays from 8:30 to 11:30 Closed all day on Tuesdays and Thursdays From 31st July onwards: Every morning from 8:30 to 12:00 The Service is closed in the afternoons. We should like to remind you that dosimeters cannot be sent to customers by internal mail. Short-term dosimeters (VCTs) must always be returned to the Service after use and must not be left on the racks in the experimental areas or in the secretariats. Dosimetry Service Tel 72155 Bldg. 24 E 011 Dosimetry.email@example.com http://cern.ch/rp-dosimetry
Introduction: Uncertainty is understood as an important component of the information seeking process, but it has not been explored as a component of reference and information service. Method: Interpretative phenomenological analysis was used to examine the practitioner perspective of reference and information service for eight academic research…
De Santis, Marco; Cesari, Elena; Ligato, Maria Serena; Nobili, Elena; Straface, Gianluca; Cavaliere, Annafranca; Caruso, Alessandro
Concern about exposure to drugs, radiation, or infection during pregnancy occur often because pregnancy is not always planned. A teratology information service offers rapid scientific counseling to all those worried about prenatal exposure. The aim of this study is to present data on the most common pharmaceutical products responsible for teratogenic risk in the one-year experience of a teratology information service in Italy. The survey was conducted among 8664 callers who contacted our Teratology Information Service in Rome between January and December 2006. Data on maternal age, gravidity, parity, maternal health status, and details of exposure (dose and timing) were collected and stored in a specific data base. Scientific counseling on prenatal exposure was given to the caller by a specialized service operator, specifying the type of risk and suggesting appropriate tests for prenatal diagnosis. Most of the people called regarding drug exposure; increased risk was present in only 5% of the pregnant women calling during pregnancy. Selective serotonin reuptake inhibitors (SSRIs) are the first category that are actually considered of increased risk to the fetus. The second category is represented by antiepileptic drugs. This experience confirms previous data that there is a high teratological risk perception among both women and physicians. The drugs estimated to present increased risk are medications used for chronic neurological diseases, mainly mood disorders and epilepsy. Preconceptional counseling for these women could be an effective strategy to prevent such exposure and to improve maternal and fetal outcome.
...), 1275 First Street NE., Washington, DC 20417. ATTN: Hada Flowers/IC 9000-0152, Service Contracting... DEPARTMENT OF DEFENSE GENERAL SERVICES ADMINISTRATION NATIONAL AERONAUTICS AND SPACE ADMINISTRATION [OMB Control No. 9000-0152: Docket 2012-0076; Sequence 16] Information Collection; Service...
Hazarika, Panna; Galligan, Stephen
Controlling warehousing operations and food inventory, administering school cafeteria activity, and measuring the profitability of food service operations are identified as food service administrative problems. A comprehensive school food services information system developed to address these problems is described. (Author/MLF)
The French customs office moves out from Prévessin (building 904) to Ferney-Voltaire on January 20th-21st-22nd. For this reason the customs office will remain closed from Wednesday 20th to Friday 22nd January included. The service will open at the French customs office in Ferney-Voltaire on Monday January 25th.
As from Thursday 11 March two containers for the collection used NESPRESSO capsules will be at your disposal: One container near Building 133 (Recuperation and Sales Service); One container near Building 904 (Goods Reception). The used capsules will be dispatched to an industrial processing centre for recycling.
This article identifies benefits of using Internet technologies in an organization's intranet or internal information system: ease-of-use, one interface, implementation cost, access, information services (flat content and interactive intranets), support desks (via Web services and e-mail), document management. Discusses the impact of intranets on…
Technological development in the world has brought many changes to libraries and their service deliveries. Many Libraries are trying to improve on their services by moving from face to face interaction to a digital environment. In this era of information explosion, many people rely on the internet for information and less ...
Information professionals are increasingly responsible not only for running traditional information and library services but also for providing an online presence for their organisation. This book shows how best practice in delivering online information services should be based on actual user needs and behaviour. A series of case studies provide real life examples of how social science information is being used in the community. The book then draws on these case studies to outline the main issues facing service providers: such as usability, metadata and management. The book concludes with a lo
Manáková, Eva; Hubicková-Heringová, Lucie; Jelínek, Richard
Care, treatment and follow-up in psychiatric and epileptic pregnant women were compared with women inquiring Czech Teratology Information Service (CZTIS) due to other exposure to drugs during pregnancy. Data were collected by CZTIS, member of European Network of Teratology Information Services from 1996. Exposed groups were compared with pregnant women exposed to drugs which were not classified as major teratogens or hyperthermia. Groups do not vary in age, reproductive history and other parameters. We observed higher frequency of miscarriage and voluntary termination of pregnancy in the group of psychiatric patients. The number of malformation in prospective follow-up cases was lower than in control group. Chronic diseases as epilepsy or psychiatric disorders have to be treated during pregnancy. Women should obtain accurate information about possible risk before pregnancy. Co-operation is needed in these cases. Physicians should keep in mind that appropriate information is to be given to the patient according to her disease, education and comprehension of the problem. If there is any doubt they should organize help for their patients.
(The English version will be available next week). L’infirmerie du CERN (bâtiment 57-Rdc) est ouverte de 8h00 à 17h30, tous les jours ouvrables. La période de 12h30 à 13h30 est réservée uniquement aux urgences, afin de respecter un moment de pause pour les infirmières. Le service médical délivre des soins de premier secours et ne peut en aucun cas se substituer au médecin traitant. Une liste de médecins, dentistes et d’autres professionnels de santé du pays de Gex et de Meyrin est disponible sur la page web du service médical et mise à jour régulièrement : http://sc-me.web.cern.ch/sc-me/ En cas d’urgence sur le site du CERN, appeler en priorité le 74444.
Librarians ... may have failed to adopt marketing theory and practices for a variety of .... of marketing principles in the context of libraries and information centres. ...... The membership fee is tax deductible as a business expense in some countries. ...... Prepared by Chin Saik Yoon, Publisher, Southbound, Penang, Malaysia, ...
The CERN infirmary (ground floor, Building 57) is open from 8.00 a.m. to 5.30 p.m. every working day. It is open for emergencies only between 12.30 and 1.30 p.m., to allow the nurses to take their lunch breaks. The Medical Service only gives first-level medical treatment and under no circumstances can it take the place of your family doctor. A list of doctors, dentists and other health professionals in the Pay de Gex and Meyrin can be consulted on the Medical Service’s regularly updated web page: http://sc-me.web.cern.ch/sc-me/ In the event of an emergency on the CERN site, the first number to call is 74444.
A. A. Al–Saraj
Full Text Available Thirty three pregnant rabbits were exposed to vapour of 10% formaldehyde (12 ppm throughout the gestation period to know its effect on newborns. The results showed no abortion or foetal mortality but there were some anomalies (23.8% among the newborns rabbits which includes: meromelia (6.8%, encephalocele (6.1%, Oligodactyly (4.1%, Umbilical hernia (3.4% and Short tail (3.4%; besides that small for date and decrease in the body weight of the newborns were also noticed. These findings suggest that formaldehyde is a teratogenic agent.
The paper gives a survey of the biotechnology information in the GDR and describes the establishment of the Biotechnology Information Service of the GDR (BioInfo GDR). BioInfo GDR is a referral database and is to provide information on information sources available in the GDR, and on institutions working in the various fields of biotechnology in the GDR. In addition, some general problems of the building and use of databases are discussed. (author). 8 refs
Poetzsch, E [Academy of Sciences, Berlin (Germany). Scientific Information Center
The paper gives a survey of the biotechnology information in the GDR and describes the establishment of the Biotechnology Information Service of the GDR (BioInfo GDR). BioInfo GDR is a referral database and is to provide information on information sources available in the GDR, and on institutions working in the various fields of biotechnology in the GDR. In addition, some general problems of the building and use of databases are discussed. (author). 8 refs.
Full Text Available Computer services are normally assumed to work well all the time. This usually happens for crucial services like bank electronic services, but not necessarily so for others, that there is no commercial interest in their operation. In this work we examined the operation and the errors of information services and tried to find clues that will help predicting the consistency of the behavior and the quality of the harvesting, which is harder because of the transient conditions and the many services and the huge amount of harvested information. We found many unexpected situations. The services that always successfully satisfy a request may in fact return part of it. A significant part of the OAI services have ceased working while many other serves occasionally fail to respond. Some services fail in the same way each time, and we pronounce them dead, as we do not see a way to overcome that. Others also always, or sometimes fail, but not in the same way, and we hope that their behavior is affected by temporary factors, that may improve later on. We categorized the services into classes, to study their behavior in more detail.
Valeria C Benavides
Full Text Available Hyperthyroidism during pregnancy is treated with the antithyroid drugs (ATD propylthiouracil (PTU and methimazole (MMI. PTU currently is recommended as the drug of choice during early pregnancy. Yet, despite widespread ATD use in pregnancy, formal studies of ATD teratogenic effects have not been performed.We examined the teratogenic effects of PTU and MMI during embryogenesis in mice. To span different periods of embryogenesis, dams were treated with compounds or vehicle daily from embryonic day (E 7.5 to 9.5 or from E3.5 to E7.5. Embryos were examined for gross malformations at E10.5 or E18.5 followed by histological and micro-CT analysis. Influences of PTU on gene expression levels were examined by RNA microarray analysis.When dams were treated from E7.5 to E9.5 with PTU, neural tube and cardiac abnormalities were observed at E10.5. Cranial neural tube defects were significantly more common among the PTU-exposed embryos than those exposed to MMI or vehicle. Blood in the pericardial sac, which is a feature indicative of abnormal cardiac function and/or abnormal vasculature, was observed more frequently in PTU-treated than MMI-treated or vehicle-treated embryos. Following PTU treatment, a total of 134 differentially expressed genes were identified. Disrupted genetic pathways were those associated with cytoskeleton remodeling and keratin filaments. At E 18.5, no gross malformations were evident in either ATD group, but the number of viable PTU embryos per dam at E18.5 was significantly lower from those at E10.5, indicating loss of malformed embryos. These data show that PTU exposure during embryogenesis is associated with delayed neural tube closure and cardiac abnormalities. In contrast, we did not observe structural or cardiac defects associated with MMI exposure except at the higher dose. We find that PTU exposure during embryogenesis is associated with fetal loss. These observations suggest that PTU has teratogenic potential.
Yang, Peng; Pan, Feng; Liu, Danhong; Xu, Yongyong
In order to construct a function model of community health service (CHS) information for development of CHS information management system, Integration Definition for Function Modeling (IDEF0), an IEEE standard which is extended from Structured Analysis and Design(SADT) and now is a widely used function modeling method, was used to classifying its information from top to bottom. The contents of every level of the model were described and coded. Then function model for CHS information, which includes 4 super-classes, 15 classes and 28 sub-classed of business function, 43 business processes and 168 business activities, was established. This model can facilitate information management system development and workflow refinement.
Hancock, Rebecca L; Koren, Gideon; Einarson, Adrienne; Ungar, Wendy J
Women and their health care providers have few reliable sources of information regarding the safety of exposures in pregnancy and lactation. Evidence-based information on these topics is provided by Teratology Information Services (TIS). Access to TIS, however, is limited in many regions, and many services have difficulty maintaining ongoing funding. The objective of this review is to highlight published reports of the effectiveness of TIS in improving maternal and neonatal health. A search of the Pub Med and Econ Lit databases was performed with no date restriction, using the search terms teratology, information, counseling, pregnancy, effectiveness, birth defects. Information disseminated from TIS has been shown to prevent congenital malformations, unnecessary pregnancy terminations, and occupational risks. TIS support optimal nutritional supplementation in pregnancy and optimal drug therapy in pregnancy and breast-feeding. In addition, they correct misperceptions of risk and facilitate knowledge transfer and translation. TIS have the potential to provide health care cost savings. TIS are vital services in supporting optimal maternal and neonatal health. A formal economic evaluation of TIS is required in order to inform resource allocation decision-making and continued funding of these services.
Panter, K E; James, L F; Gardner, D R
Many species of lupines contain quinolizidine or piperidine alkaloids known to be toxic or teratogenic to livestock. Poison-hemlock (Conium maculatum) and Nicotiana spp. including N. tabacum and N. glauca contain toxic and teratogenic piperidine alkaloids. The toxic and teratogenic effects from these plant species have distinct similarities including maternal muscular weakness and ataxia and fetal contracture-type skeletal defects and cleft palate. It is believed that the mechanism of action of the piperidine and quinolizidine alkaloid-induced teratogenesis is the same; however, there are some differences in incidence, susceptible gestational periods, and severity between livestock species. Wildlife species have also been poisoned after eating poison-hemlock but no terata have been reported. The most widespread problem for livestock producers in recent times has been lupine-induced "crooked calf disease." Crooked calf disease is characterized as skeletal contracture-type malformations and occasional cleft palate in calves after maternal ingestion of lupines containing the quinolizidine alkaloid anagyrine during gestation days 40-100. Similar malformations have been induced in cattle and goats with lupines containing the piperidine alkaloids ammodendrine, N-methyl ammodendrine, and N-acetyl hystrine and in cattle, sheep, goats, and pigs with poison-hemlock containing predominantly coniine or gamma-coniceine and N. glauca containing anabasine. Toxic and teratogenic effects have been linked to structural aspects of these alkaloids, and the mechanism of action is believed to be associated with an alkaloid-induced inhibition of fetal movement during specific gestational periods. This review presents a historical perspective, description and distribution of lupines, poison-hemlock and Nicotiana spp., toxic and teratogenic effects and management information to reduce losses.
Oh, Jeong Hoon; Kim, Tae Whan; Yi, Ji Ho; Chun, Young Choon; Yoo, Jae Bok; Yoo, An Na; Choi, Heon Soo
Domestic INIS project has carried out various activities on supporting a decision-making for INIS Secretariat, exchanges of the statistical information between INIS and the country, and technical assistance for domestic end-users using INIS database. Based on the construction of INIS database sent by member states, the data published in the country has been gathered, collected, and inputted to INIS database according to the INIS reference series. Using the INIS output data, it has provided domestic users with searching INIS CD-ROM DB, INIS online database, INIS SDI service, and non-conventional literature delivery services. INIS2 DB Host site in Korea has serviced users of domestic and INIS member countries. In order to maintain the same data as Vienna center, the data update process has been performed. Also, publicity information activities were performed by many ways. To construct digital information infrastructure, we changed web server of KORNIS21 and we reconstruct digital library system as separation of KAERI network system. We constructed patent trend analysis system and new SDI service system. Also we collected Web DB, digital journals and so on and made an effort on operation of knowledge management system and research documents management. We have inputted over 4,000 records per year since 2009 and the input amount this year has reached 4,284 records. In order to input the comprehensive domestic publication related to nuclear energy, and rise in position of the national center, it is necessary to continue efforts and support budgets. We expect the INIS2 DB Host site will make a contribution to the improvement of productivity in the nuclear energy research as well as the diffusion of information about nuclear energy. We provided users with stable services changing web server of KORNIS21. Also we contributed to the improvement of researcher's productivity by constructing patent trend analysis system, new SDI service system and provided users with services
Techniques de l'Ingénieur has been part of the selection of databases offered by the Scientific Information Service for the last five years. Unfortunately, as a consequence of budget reductions, and after careful consideration of all available options, we have to end this subscription. It will be still possible to purchase access to individual chapters via the Library services. Furthermore, we are considering ending our subscriptions to Web of Science and Springer Materials (the Landolt-Börnstein database) during the course of 2015. We thank you for your understanding and welcome your feedback to firstname.lastname@example.org
Oh, Jeong Hoon; Kim, Tae Whan; Lee, Kyu Jeong; Yi, Ji Ho; Chun, Young Choon; Yoo, Jae Bok; Yoo, An Na
Domestic INIS project has carried out various activities on supporting a decision-making for INIS Secretariat, exchanges of the statistical information between INIS and the country,and technical assistance for domestic end-users using INIS database. Based on the construction of INIS database sent by member states, the data published in the country has been gathered, collected, and inputted to INIS database according to the INIS reference series. Using the INIS output data, it has provided domestic users with searching INIS CD-ROM DB, INIS online database, INIS SDI service, and non-conventional literature delivery services. INIS2 DB Host site in Korea has serviced users of domestic and INIS member countries. In order to maintain the same data as Vienna center, the data update process has been performed. Also, publicity information activities were performed by many ways. To construct digital information infrastructure, we changed web server of NUCLIS21 and upgraded information management manager system and constructed full text DB on research and technical reports. Also we collected web DB, digital journals and so on and made an effort on operation of knowledge management system and research documents management. We have inputted over 3,000 records per year since 2002 and the input amount this year has reached 3,738 records. In order to input the comprehensive domestic publication related to nuclear energy, and rise in position of the national center, it is necessary to continue efforts and support budgets. We expect the INIS2 DB Host site will make a contribution to the improvement of productivity in the nuclear energy research as well as the diffusion of information about nuclear energy. We provided users with stable services changing web server of NUCLIS21. Also we contributed to the improvement of librarians' productivity by upgrading information management manager system and provided users with services of web DB, digital journals and so on
The research paper focused on the school library services as a necessity to all primary and secondary schools. The study discussed the concept and significance of school libraries in the community, it also explained the reading habits of school children as they utilize the library and the adoption of Information and ...
Full Text Available In the last few years, a new type of synchronous social networking services (SNSs has emerged—social live streaming services (SLSSs. Studying SLSSs is a new and exciting research field in information science. What information behaviors do users of live streaming platforms exhibit? In our empirical study we analyzed information production behavior (i.e., broadcasting as well as information reception behavior (watching streams and commenting on them. We conducted two quantitative investigations, namely an online survey with YouNow users (N = 123 and observations of live streams on YouNow (N = 434. YouNow is a service with video streams mostly made by adolescents for adolescents. YouNow users like to watch streams, to chat while watching, and to reward performers by using emoticons. While broadcasting, there is no anonymity (as in nearly all other WWW services. Synchronous SNSs remind us of the film The Truman Show, as anyone has the chance to consciously broadcast his or her own life real-time.
Frasincar, F.; Houben, G.J.P.M.; Barna, P.; Vasilecas, O.; Eder, J.; Caplinskas, A.
Hera is a model-driven methodology for designing Web information systems. In the past a CASE tool for the Hera methodology was implemented. This software had different components that together form one centralized application. In this paper, we present a distributed Web service-oriented architecture
... DEPARTMENT OF AGRICULTURE Farm Service Agency Information Collection; Customer Data Worksheet Request for Service Center Information Management System (SCIMS) Record Changes AGENCY: Farm Service... Customer Data Worksheet Request for Service Center Information Management System (SCIMS) that contains the...
Allard, Daniel A.; Gladden, Roy E.; Wright, Jesse J.; Hy, Franklin H.; Rabideau, Gregg R.; Wallick, Michael N.
This software is provided by the Mars Relay Operations Service (MaROS) task to a variety of Mars projects for the purpose of coordinating communications sessions between landed spacecraft assets and orbiting spacecraft assets at Mars. The Information Management Service centralizes a set of functions previously distributed across multiple spacecraft operations teams, and as such, greatly improves visibility into the end-to-end strategic coordination process. Most of the process revolves around the scheduling of communications sessions between the spacecraft during periods of time when a landed asset on Mars is geometrically visible by an orbiting spacecraft. These relay sessions are used to transfer data both to and from the landed asset via the orbiting asset on behalf of Earth-based spacecraft operators. This software component is an application process running as a Java virtual machine. The component provides all service interfaces via a Representational State Transfer (REST) protocol over https to external clients. There are two general interaction modes with the service: upload and download of data. For data upload, the service must execute logic specific to the upload data type and trigger any applicable calculations including pass delivery latencies and overflight conflicts. For data download, the software must retrieve and correlate requested information and deliver to the requesting client. The provision of this service enables several key advancements over legacy processes and systems. For one, this service represents the first time that end-to-end relay information is correlated into a single shared repository. The software also provides the first multimission latency calculator; previous latency calculations had been performed on a mission-by-mission basis.
Maruyama, Yukio; Mizuno, Hiromi; Shoda, Kohei; Sekine, Yasuhiro.
For the purpose of improving the intelligent productivity in offices, the introduction of PC-LAN system by the initiative of users has been advanced. In this example, by connecting many personal computers, the information service system that possesses the information on the business of power stations in common was constructed, and intelligent productivity was improved. This information service system is that in which all users are the sponsor as the users and the offerer of information are united, therefore, high conscience level is required for individual users, and the attentive device for the easiness of use was exercised so as to always maintain newest information. The background of introducing this system is explained. The information systems in power stations are the system related to operation control, preventive maintenance and so on and the system for helping the routine works of personnel. The main functions are the offer of the operational data of power stations, the offer of the information on the expected visitors to the PR hall of nuclear power stations, electronic information exchange and so on. The constitution and the features of the system are reported. (K.I.)
Beyler, Roger E.; Meyers, Vera Kolb
Teratogens are agents which act during pregnancy producing physical/functional defects in the embryo, fetus, or offspring. Discusses teratogenic hazards in the workplace and academic environment, classes of teratogenic compounds, precautions for interpreting Teratogen List from Registry of Toxic Effects of Chemical Substances (RTECS), and how…
Full Text Available End-users play a critical role in the effective implementation and running of an information security program in any organization. The success of such a program depends primarily on the effective implementation and execution of associated information security policies and controls and the resultant behavior and actions of end-users. However, end-users often have negative perception of information security in the organization and exhibit non-compliance. In order to improve compliance levels, it is vital to improve the image of information security in the minds of end-users. This paper borrows the concepts of brands and branding from the domain of marketing to achieve this objective and applies these concepts to information security. The paper also describes a process for creating the information security service brand in the organization.
Zhang, Shaochen; Li, Yun
Individual owned forests have boomed in the last decade in China. Hundreds of millions of private forest owners have emerged since years of afforestation practice and collective forest ownership reform. Most of those private forest owners are former peasants living in afforestation areas. They thirst for forestry information, such as technique knowledge, forestry policies, finance, marketing, etc. Unfortunately the ways they could get certain information are very limit. Before internet time, Local governments are the main channel they search helps for useful information and technique supports. State and local governments have paid much attention to provide necessary forestry technique supports to those small forest owners and provided varies training projects, issued official forestry information through their websites. While, as state government expands household contract system in the management of collective forestry land, the number of individual forest owners is bumping up in future 5 years. There is still a gap between supplying ability and requirement of forestry information. To construct an effective forestry information service system in next 3-5 year can bridge the gap. This paper discusses the framework of such an information service system.
... Services Group, Inc., Commercial/Actuarial/ Information Delivery Services (IDS)/Corporate & Financial... Assistance (TAA) applicable to workers and former workers of Hartford Financial Services Group, Inc., Commercial/ Actuarial/Information Delivery Services (IDS)/Corporate & Financial Reporting group, Hartford...
Ito, Takumi; Ando, Hideki; Suzuki, Takayuki; Ogura, Toshihiko; Hotta, Kentaro; Imamura, Yoshimasa; Yamaguchi, Yuki; Handa, Hiroshi
Half a century ago, thalidomide was widely prescribed to pregnant women as a sedative but was found to be teratogenic, causing multiple birth defects. Today, thalidomide is still used in the treatment of leprosy and multiple myeloma, although how it causes limb malformation and other developmental defects is unknown. Here, we identified cereblon (CRBN) as a thalidomide-binding protein. CRBN forms an E3 ubiquitin ligase complex with damaged DNA binding protein 1 (DDB1) and Cul4A that is important for limb outgrowth and expression of the fibroblast growth factor Fgf8 in zebrafish and chicks. Thalidomide initiates its teratogenic effects by binding to CRBN and inhibiting the associated ubiquitin ligase activity. This study reveals a basis for thalidomide teratogenicity and may contribute to the development of new thalidomide derivatives without teratogenic activity.
Teratogenicity and brain aromatase-induction of monosodium glutamate in estrogen-responsive mosaic transgenic zebra fish Danio rerio. Tamer Said Abdelkader, Chang Seo-Na, Kim Tae-Hyun, Song Juha, Kim Dongso, Jae-Hak Park ...
Full Text Available This paper presents a method on the semantic access environment, which can solve the problem about how to identify the correct natural disaster emergency knowledge and return to the demanders. The study data is natural disaster knowledge text set. Firstly, based on the remote sensing emergency knowledge database, we utilize the sematic network to extract the key words in the input documents dataset. Then, using the semantic analysis based on words segmentation and PLSA, to establish the sematic access environment to identify the requirement of users and match the emergency knowledge in the database. Finally, the user preference model was established, which could help the system to return the corresponding information to the different users. The results indicate that semantic analysis can dispose the natural disaster knowledge effectively, which will realize diversified information service, enhance the precision of information retrieval and satisfy the requirement of users.
Manzarbanoo Shojaei fard
Full Text Available Background & Objectives: Teratology is a branch of embryology science that studies causes, mechanisms and abnormal pattern development. Embryo growth traumatic factors during pregnancy are called teratogens that some teratogens pass the placental barrier and cause adverse effect during development stages and malformation, however a drug may improve general health of the mother, but it might be poisonous for embryo and cause diverse malformation. Since study of embryo health and risk factor in this stage is important, the aim of this review article was the investigation of some types of teratosgens (such as radiation, infectious agents, heat disorders, maternal conditions and particularly the effect of teratogenic drugs on embryo including some legal drugs (such as acetaminophen, thalidomide, acyclovir, sedatives and anticonvulsants and illegal drugs (such as nicotine, alcohol, cocaine and marijuana. Conclusion: In general, teratogens depending on the type and duration of exposure in pregnancyperiod, adversely affect embryo and cause various disorders. A better understanding of these teratogens can contribute to prevent these defects, since many other drugs with similar effects and lower teratogenicity can be used to improve mothers’ health.
In coordination with the Information Infrastructure Task Force (IITF), the Office of Management and Budget (OMB) is promoting the establishment of an agency-based Government Information Locator Service (GILS) to help the public locate and access information throughout the Federal Government. This report presents a vision of how GILS will be implemented. Working primarily with OMB and the Locator Subgroup of the Interagency Working Group on Public Access, Eliot Christian of the US Geological Survey prepared this report under the auspices of the IITF Committee on Information Policy. This vision of GILS has also received extensive review by various Federal agencies and other interested parties, including some non-Federal organizations and by the general public through notices in both the Federal Register and the Commerce Business Daily and at a public meeting held in December, 1993. As part of the Federal role in the National Information Infrastructure, GILS will identify and describe information resources throughout the Federal government, and provide assistance in obtaining the information. It will be decentralized and will supplement other agency and commercial information dissemination mechanisms. The public will use GILS directly or through intermediaries, such as the Government Printing Office, the National Technical Information Service, the Federal depository libraries, other public libraries, and private sector information services. Direct users will have access to a GILS Core accessible on the Internet without charge. Intermediate access may include kiosks, "800 numbers", electronic mail, bulletin boards, fax, and off-line media such as floppy disks, CD-ROM, and printed works. GILS will use standard network technology and the American National Standards Institute Z39.50 standard for information search and retrieval so that information can be retrieved in a variety of ways. Direct users will eventually have access to many other Federal and non
Adams, Dennis; Lee, Chee-Seng
Logistics can be defined as the process of strategically managing the acquisition, movement, and storage of materials, parts, and finished inventory (and the related information flow) through the organization and its marketing channels in a cost effective manner. It is concerned with delivering the right product to the right customer in the right place at the right time. The logistics function is composed of inventory management, facilities management, communications unitization, transportation, materials management, and production scheduling. The relationship between logistics and information systems is clear. Systems such as Electronic Data Interchange (EDI), Point of Sale (POS) systems, and Just in Time (JIT) inventory management systems are important elements in the management of product development and delivery. With improved access to market demand figures, logisticians can decrease inventory sizes and better service customer demand. However, without accurate, timely information, little, if any, of this would be feasible in today's global markets. Information systems specialists can learn from logisticians. In a manner similar to logistics management, information logistics is concerned with the delivery of the right data, to the ring customer, at the right time. As such, information systems are integral components of the information logistics system charged with providing customers with accurate, timely, cost-effective, and useful information. Information logistics is a management style and is composed of elements similar to those associated with the traditional logistics activity: inventory management (data resource management), facilities management (distributed, centralized and decentralized information systems), communications (participative design and joint application development methodologies), unitization (input/output system design, i.e., packaging or formatting of the information), transportations (voice, data, image, and video communication systems
Southon, Frank Charles Gray; Sauer, Chris; Dampney, Christopher Noel Grant (Kit)
Abstract Objective: To identify impediments to the successful transfer and implementation of packaged information systems through large, divisionalized health services. Design: A case analysis of the failure of an implementation of a critical application in the Public Health System of the State of New South Wales, Australia, was carried out. This application had been proven in the United States environment. Measurements: Interviews involving over 60 staff at all levels of the service were undertaken by a team of three. The interviews were recorded and analyzed for key themes, and the results were shared and compared to enable a continuing critical assessment. Results: Two components of the transfer of the system were considered: the transfer from a different environment, and the diffusion throughout a large, divisionalized organization. The analyses were based on the Scott-Morton organizational fit framework. In relation to the first, it was found that there was a lack of fit in the business environments and strategies, organizational structures and strategy-structure pairing as well as the management process-roles pairing. The diffusion process experienced problems because of the lack of fit in the strategy-structure, strategy-structure-management processes, and strategy-structure-role relationships. Conclusion: The large-scale developments of integrated health services present great challenges to the efficient and reliable implementation of information technology, especially in large, divisionalized organizations. There is a need to take a more sophisticated approach to understanding the complexities of organizational factors than has traditionally been the case. PMID:9067877
Yamada, Hiroshi; Kawaguchi, Akira
Grid computing and web service technologies enable us to use networked resources in a coordinated manner. An integrated service is made of individual services running on coordinated resources. In order to achieve such coordinated services autonomously, the initiator of a coordinated service needs to know detailed service resource information. This information ranges from static attributes like the IP address of the application server to highly dynamic ones like the CPU load. The most famous wide-area service discovery mechanism based on names is DNS. Its hierarchical tree organization and caching methods take advantage of the static information managed. However, in order to integrate business applications in a virtual enterprise, we need a discovery mechanism to search for the optimal resources based on the given a set of criteria (search keys). In this paper, we propose a communication protocol for exchanging service resource information among wide-area systems. We introduce the concept of the service domain that consists of service providers managed under the same management policy. This concept of the service domain is similar to that for autonomous systems (ASs). In each service domain, the service information provider manages the service resource information of service providers that exist in this service domain. The service resource information provider exchanges this information with other service resource information providers that belong to the different service domains. We also verified the protocol's behavior and effectiveness using a simulation model developed for proposed protocol.
Jabeen, R.; Tahir, M.; Waqas, S.
Background: Lead remains a considerable occupational and public health problem, which is known to cause a number of adverse effects in both men and women. Conflicting reports have appeared on lead induced nephrotoxicity in experimental studies in the past. There is hardly any work on its teratogenic effects on kidney. Present study was therefore designed to investigate the effects of lead acetate on developing kidney. Methods: Twelve mice were used as experimental model and were divided into two groups of six animals each; group A served as control group and B was used as an experimental group. Lead acetate (10 mg/kg) dissolved in 0.02 ml of distilled water was administered as a single daily dose orally to group B whereas weight related amount of distilled water was given to group A for the entire period of experiment. On 18 day of gestation foetuses were dissected free of uterine wall under the dissecting microscope and were sacrificed; kidneys were removed and fixed in 10% formalin, dehydrated in ascending grades of alcohol, cleared in xylene and infiltrated with filtered paraffin. The paraffin blocks were made and five micron thin sections were obtained using a rotary microtome. The sections were stained with Hematoxylin and eosin and, PAS; these were examined under light microscope. Results: Significant decrease in cortical thickness was observed which varied from 578.6 +- 1.4 mu m in group A to 515.6 +- 5 mu m in group B (p<0.001). Diameter of renal corpuscles varied from 57.7 +- 0.07 mu m in group A to 50.5 +- 0.07 mu m in group B (p<0.001). Moderate cortical tubular atrophy showing thickening of endothelial basement membrane in glomeruli, desquamated epithelium with degenerated nuclei in proximal and distal tubules were observed in group B in contrast to group A. Conclusion: The results of the investigation indicated that lead acetate administration to the dams produced deleterious effects on the developing kidney in mice. (author)
Kato, F.; Ootsuyama, A.; Nomoto, S.; Norimura, T.
Experimental studies with mice have established that fetuses at midgestational stage are highly susceptible to malformation at high, but not low, doses of radiation. When DNA damage is produced by a small amount of radiation, it is efficiently eliminated by DNA repair. However, DNA repair is not perfect. There must be defense mechanisms other than DNA repair. In order to elucidate the essential role of p53 gene in apoptotic tissue repair, we compared the incidence of radiation-induced malformations and deaths (deaths after day 10) in wild-type p53 (+/+) mice and null p53 (-/-) mice. For p53 (+/+) mice, an X-ray dose of 2 Gy given at a high dose-rate (450 mGy/min) to fetuses at 9.5 days of gestation was highly lethal and considerably teratogenic whereas it was only slightly lethal but highly teratogenic for p53 (-/-) fetuses. This reciprocal relationship of radiosensitivity to malformations and deaths supports the notion that fetal tissues have a p53 -dependent idguardianln of the tissue that aborts cells bearing radiation-induced teratogenic DNA damage. When an equal dose of 2 Gy given at a 400-fold lower dose-rate (1.2 mGy/min), this dose became not teratogenic for p53 (+/+) fetuses exhibiting p53 -dependent apoptosis, whereas this dose remained teratogenic for p53 (-/-) fetuses unable to carry out apoptosis. Furthermore, when the dose was divided into two equal dose fractions (1+1 Gy) at high dose rate, separated by 24 hours, the incidences of malformations were equal with control level for p53 (+/+), but higher for p53 (-/-) mice. Hence, complete elimination of teratogenic damage from irradiated tissues requires a concerted cooperation of two mechanisms; proficient DNA repair and p53-dependent apoptotic tissue repair
Fang Zhiyuan; Wei Li
Health Information eXchange (HIX) is a part of Happiness Cloud Service Platform of Happiness Guangdong in Guangdong Province of China based on innovation of cloud-based business model. This article illustrates the hospital health care business services system based on cloud computing. major business functions of HIX includes integrated mobile medical information services, and mobile health information services. Key cloud service platform capabilities include appointment of HIX registration, d...
This paper examines the profession of information brokerage through a look at types of services provided, and through a discussion of major issues, including that of fee for service. The types of information broker and free-lance librarian services are identified: (1) non-profit reference and research services administered by public libraries and…
Full Text Available The peculiarities and priorities of the informational services regional market formation as a part of network model of the economic development are described in this article. The authors present the classification of the factors which have an influence on the effectiveness of the informational services regional market development. Theoretical aspects of the informational services regional market effective development are shown.
... Management, Inc., Corporate Service Group, Information Technology (IT) Division, Including On-Site Leased... Information Management, Inc., Corporate Service Group, Information Technology (IT) Division, including on-site... location of Iron Mountain Information Management, Inc., Corporate Service Group, Information Technology (IT...
Safety of nuclear power plants is one of the most important conditions for their acceptance. Safety is being acheived by numerous methods and techniques in phase of design, manufacturing and maintenance of the nuclear power plants. In-service Inspection (ISI) has a significant role in avoidances of failure in components of nuclear power plants just the same as in assurance of their integrity. Non-destructive examinations are performed periodically in accordance with 10 CFR 50 50.55a and ASME Boiler and Pressure Vessel Code section XI which is referenced by 10 CFR 50.55a. Nondestructive examinations provide information about a current condition of equipment at nuclear power plants and about any damage, defect or degradation mechanism. A lot of effort is often spent in situations in which the probability of failure and their effects on safety have a very low impact. Practical experience shows that failures can often occur at locations where the inspection has never been performed. Costs and expenses of in-service inspections are very high. Therefore, the accent has to be on locations with significant risk to safety. Many years of nuclear power plants' operation and maintenance have resulted in a more broad knowledge of degradation mechanism and the most susceptible locations and huge databases of different nuclear power plants' components. U.S. Nuclear Regulatory Commission (NRC) and the nuclear industry have recognized that probabilistic risk assessment (PRA) has developed and changed to be more useful in improvement of traditional engineering approaches in nuclear power plants regulation. After the publication of its policy statement on the use of PRA in nuclear regulatory activities, the Commission ordered the NRC staff to develop a regulatory framework that incorporated risk insights. The American Society of Mechanical Engineers (ASME) initiated Code Case N-560, N-577, and N-578 that address the importance of categorization and inspection of piping using risk
Xin Pingping; Lu Yan
According to the development of the internet and multimedia technology, the information service models in the contemporary library become both of the traditional and digital information service. The libraries in each country do their best to make the voluminous information and the complex technology be High-integrated in the background management, and also make the front interface be more and more convenient to the users. The essential characteristics of the information service of the contemporary library are all-in-one and humanness. In this article, we will describe several new hot information service models of the contemporary library in detail, such as individualized service, reference service, reference service and strategic information service. (authors)
Hansen, Ernst; Meyer, Otto A.
A teratogenicity study on butylated hydroxyanisole (BHA) was carried out in SPF New Zealand White rabbits. BHA was given by gavage from day 7–18 of the gestation period in doses of 0, 50, 200 and 400 mg/kg body wt./day. The fetuses were removed on day 28. No effect related to the treatment with BHA...
It also showed that 31.2% of all the malformed litters had multiple congenital malformations. It also showed that the experimental rats had nine resorption sites while control had none. This demonstrates that the water extract of Momordica charantia is teratogenic in Sprague Dawley rats and should be used with caution in ...
Full Text Available Background: Obsessive-compulsive disorders and depression have a high prevalence during pregnancy therefore, pregnant women may take clomipramine and also take other drugs or consume foods that contain caffeine. As investigations about the teratogenic effects of clomipramine and its concurrent administration with caffeine during organogenesis period are scarce, we aimed to study the teratogenicity of simultaneous administration of clomipramine and caffeine in rat fetus.Methods: After dividing 42 pregnant rats to several case and control groups, we injected different doses of caffeine and clomipramine to the animals. All the injections were performed on the eighth until the 15th day of pregnancy. We removed the fetuses on the 17th day of pregnancy and studied the morphological features and apparent anomalies of the fetuses macroscopically. Results: We found a significant rate of mortality, apparent anomalies, abnormal torsion, shrinkage of skin and subcutaneous bleeding in fetuses of rats receiving high doses of caffeine or a combination of caffeine and clomipramine. Statistical analysis of the data revealed a significant increase (P?0.001 in teratogenicity of high doses of caffeine and its combination with clomipramine. Conclusion: This study implies simultaneous intake of high amounts of caffeine and clomipramine lead to teratogenicity. We recommend pregnant women to avoid uncontrolled consumption of foods that contain caffeine or drugs that contain high amounts of this substance. They should not also take clomipramine with caffeine in the first trimester of pregnancy.
Shi , Xiaohui; Chen , Tian’en
International audience; According to characteristics of tea industry information service, this paper have built service quality evaluation index system for tea industry information service quality, R-cluster analysis and multiple regression have been comprehensively used to contribute evaluation model with a high practice and credibility. Proved by the experiment, the evaluation model of information service quality has a good precision, which has guidance significance to a certain extent to e...
Sharma Grover, A
Full Text Available The authors present the design, development and pilot process of the Lwazi Community Communication Service (LCCS), a multilingual automated telephone-based information service. The service acts as a communication and dissemination tool that enables...
The purpose of this research was to identify the service factors that influence judgments of customer satisfaction in the academic library/media center. The study, conducted at Florida State University examined the relative importance of these determinants of service quality and compared these results to earlier studies conducted with customers of…
Scupola, Ada; Henten, Anders; Nicolajsen, Hanne Westh
The concept of e-services has gained increasing use during the past decade. There is, however, no general agreement as to the precise meaning and scope of the term. The research purpose of the present chapter is, therefore, to discuss the e-service concept, its strengths and scope, and thereby co...
Shipman, Todd; Bannon, Susan H.; Nunes-Bufford, Kimberly
Research on information literacy and educators has focused on preservice educators and learning information literacy skills. Little research exists on in-service educators and their information literacy skills. Purposes of this study were to identify information sources that in-service educators used; to determine relationships between information…
... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Information technology... SPECIAL CATEGORIES OF CONTRACTING ACQUISITION OF INFORMATION TECHNOLOGY General 39.104 Information technology services. When acquiring information technology services, solicitations must not describe any...
... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Information Resources... FUNCTIONS Central Offices § 105-53.143 Information Resources Management Service. (a) Creation and authority. The Information Resources Management Service (IRMS), headed by the Commissioner, Information Resources...
Marketing Information Products and Services : A Primer for Librarians and Information Professionals. Couverture du livre Marketing Information Products and Services : A Primer for Librarians and Information Professionals. Directeur(s) : Abhinandan K. Jain, Ashok Jambhekar, T.P.Rama Rao et S. Sreenivas Rao. Maison(s) ...
Naiyan, Yu; And Others
Describes the Chemical Integrated Information Service Network (ChI2Net), a comprehensive online information service system which includes chemical, technical, economic, market, news, and management information based on computer and modern communication technology that was built by the China National Chemical Information Centre. (Author/LRW)
... Services Group, Inc., Commercial/Actuarial/ Information Delivery Services (IDS)/Corporate & Financial... workers and former workers of Hartford Financial Services Group, Inc., Commercial/Actuarial/Information Delivery Services (IDS)/Corporate & Financial Reporting group, Hartford, Connecticut (The Hartford-IDS...
Kessler, Ridley R., Jr.; Barkley, Dan
Discusses the development of electronic government publications and the resulting standards and service needs. Focuses on results of a report on the impact that electronic information has brought to bear on depository library services. Includes 11 draft Depository Library Public Service Guidelines for government information. (AEF)
... collections established in the regulation are necessary for FSA to monitor and account for loan security... DEPARTMENT OF AGRICULTURE Farm Service Agency Information Collection; Direct Loan Servicing... collection that supports Direct Loan Servicing-Regular programs. The information is used to determine...
Leach, Karen; Smallen, David
A study examined the cost of information-technology support services in higher education institutions. The report describes the project's origins and work to date and reports initial results in three areas: network services, desktop repair services, and administrative information systems, looking in each case at economies of scale, outsourcing…
Maryland Cleaning & Abatement Services Corp. (the Company) is located in Baltimore, Maryland. The settlement involves renovation activities conducted at property constructed prior to 1978, located in Baltimore, Maryland.
Doderer, Mark S; Burkhardt, Cory; Robbins, Kay A
Many bioinformatics algorithms and data sets are deployed using web services so that the results can be explored via the Internet and easily integrated into other tools and services. These services often include data from other sites that is accessed either dynamically or through file downloads. Developers of these services face several problems because of the dynamic nature of the information from the upstream services. Many publicly available repositories of bioinformatics data frequently update their information. When such an update occurs, the developers of the downstream service may also need to update. For file downloads, this process is typically performed manually followed by web service restart. Requests for information obtained by dynamic access of upstream sources is sometimes subject to rate restrictions. SideCache provides a framework for deploying web services that integrate information extracted from other databases and from web sources that are periodically updated. This situation occurs frequently in biotechnology where new information is being continuously generated and the latest information is important. SideCache provides several types of services including proxy access and rate control, local caching, and automatic web service updating. We have used the SideCache framework to automate the deployment and updating of a number of bioinformatics web services and tools that extract information from remote primary sources such as NCBI, NCIBI, and Ensembl. The SideCache framework also has been used to share research results through the use of a SideCache derived web service.
Marketing library and information services in academic libraries in Niger State, Nigeria. ... This study was designed to investigate the marketing of library services in academic libraries in Niger state, ... EMAIL FULL TEXT EMAIL FULL TEXT
Full Text Available the service actually makes. This paper discusses specifically the impact an information service has on the ability of natural science researchers to perform their research effectively and efficiently. A focus group, short survey and 15 interviews were...
M.Tech. Service Oriented Architecture has many advantages. For example, organisations can align business with Information Technology, reuse the developed functionality, reduce development and maintain cost for applications. Organisations adopt Service Oriented Architecture with the aim of automating and integrating business processes. However, it has information security vulnerabilities that should be considered. For example, applications exchange information across the Internet, where it ...
Wakeley, P J; Marshall, S B; Foster, E C
In an increasingly information-based society, hospitals need a variety of information for multiple purposes--direct patient care, staff development and training, continuing education, patient and community education, and administrative decision support. Health science library and information services play a key role in providing broad-based information support within the hospital. This guide identifies resources that will help administrators plan information services that are appropriate to their needs.
Harvey, John F.
The first of two articles describes changes in information services in Iran since the Islamic revolution. Topics covered include the publishing industry, library collections and technical services, reference services, library personnel, information service administration, library education, and professional associations. The second is a call for…
David J. Snyder
Full Text Available La historia contemporánea neerlandesa sigue siendo un tema poco investigado en los Estados Unidos. Aunque los científicos sociales americanos han apreciado por mucho tiempo el valor de los estudios de neerlandeses, historiadores norteamericanos han tardado en desarrollar la historiografía contemporánea neerlandesa, debido en parte a la escasez de fuentes utiles en las colecciones públicas. Este artículo está destinado a servir como una introducción a los documentos del Servicio de Información de los Países Bajos (NIS, en neerlandés, la Regerings Voorlichtingsdienst, que ahora están abiertas al estudio, y una invitación a los académicos para incluir los Países Bajos en sus programas de investigación. Administrada por la Holland Historical Trust y ubicada en el Holland Museum of Holland, Michigan, este depósito de materiales contemporáneos en lengua neerlandesa es único en América del Norte. La colección NIS en el Museo de Holanda es un excelente punto de partida para estudiar la contemporaneidad de los Países Bajos. Una serie de acontecimientos contemporáneos se han desarrollado en Holanda, y su estudio podría enseñar a los lectores la versión neerlandesa de estos eventos._____________ABSTRACT:Contemporary Dutch history remains an under-researched topic in the United States. Though American social scientists have long appreciated the value of Dutch studies, American historians have been slow to develop contemporary Dutch historiography due in part to a dearth of comprehensive sources in public collections. This article is meant to serve as an introduction to the papers of the Netherlands Information Service (NIS; in Dutch, the Regerings Voorlichtingsdienst, which are now open for study, and an invitation to scholars to include the contemporary Netherlands in their research agendas. Held by the Holland Historical Trust and housed in the Holland Museum of Holland, Michigan, this repository of contemporary Dutch materials
Linderman, Richard W; Linderman, Mark H; Lin, Chun-Shin
.... The specific core service accelerated by FPGAs is the brokering of XML metadata of publications against the XPATH logical predicates expressing the types of publications that the subscribers wish to receive...
Harris, Lesley Ellen
Explains e-commerce and discusses how it can be used by special libraries. Highlights include library goals; examples of successful uses of e-commerce; how e-commerce can improve information services, including access to information, new information resources, delivery of information, and broadening information markets; and developing an…
Thomas W. Sadler
Full Text Available A long standing axiom in the field of teratology states that the teratogenic period, when most birth defects are produced, occurs during the third to eighth weeks of development post-fertilization. Any insults prior to this time are thought to result in a slowing of embryonic growth from which the conceptus recovers or death of the embryo followed by spontaneous abortion. However, new insights into embryonic development during the first two weeks, including formation of the anterior-posterior, dorsal-ventral, and left-right axes, suggests that signaling pathways regulating these processes are prime targets for genetic and toxic insults. Establishment of the left-right (laterality axis is particularly sensitive to disruption at very early stages of development and these perturbations result in a wide variety of congenital malformations, especially heart defects. Thus, the time for teratogenic insults resulting in birth defects should be reset to include the first two weeks of development.
To answer the question of any induced hazards in progeny by an exogeneous factor it is necessary to differentiate between mutagenic and teratogenic action. Mutations can be caused by ionisizing radiations and chemicals, e.g. cytostatic drugs. After exposure to mutagenic agents a conception should be prevented for a time of 3 months to avoid a fertilization of a germ cell that has been effected during a very sensible phase. In case of conception during mutagenic exposure it is possible to detect chromosome aberrations by prenatal diagnosis after amniocentesis. The spectrum of possible teratogens is extensive and less specific than that of mutagenic agents. Factors established as embryotoxic in man are for instance radiation, several drugs and some virus infections. They have been known to cause malformations in the fetus, if these events take place during a certain critical period of organogenesis. (orig.) [de
Outsourcing is a management strategy that is gradually proving its worth in library ... such as cost cutting, knowledge and skills acquisition and economies of scale. ... Keywords: Information Communication Technology, Information Systems, ...
Information Communication Technology in Nigerian Libraries. Murtala Aliyu ... The focus of this paper is on how to improve services in libraries and information centers in. Nigeria by ..... games, video and educational materials. Database on ...
Cartels often control basic services in these informal settlements, charging ... It will generate practical knowledge on how formal and informal land tenure, ... Researchers will also assess how these tools and planning processes can be used to ...
Moriarty, D D
There is significant opportunity for health service providers to gain competitive advantage through the innovative use of strategic information systems. This analysis presents some key strategic information systems issues that will enable managers to identify opportunities within their organizations.
Full Text Available The use of immunosuppressive medication such as Azathioprine, methoterxate and mercaptopurine in treatment of rheumatic disease in women at childbearing age has some risks of teratogeniesis. Cyclosporine is one of the newer medicines, which has been introduced for this disease but little is known about its teratogenicity. This study was designed to investigate the possible teratogenicity of this drug by using cultured rat limb bud cells, which were obtained from rat embryos 13 days after conception. Cells were incubated in trypsin-EDTA solution for 30 min at 37°C and then filtered through 50 µm nylon filters. The resultant cell suspension was cultivated in 1 ml Dulbecco modified Eagle medium (DMEM containing 10% fetal bovine serum and 445 µg/L L-glutamine at 37°C with 5% CO2. After 8 days of culture the differentiated foci extract were measured by staining with 1% alcian blue. To assess the teratogenic effects of cyclosporine, it was placed in the culture well together with the cells. Results showed that the decrease in the expression of the extracellular matrix at dose of 0.01 molar of cyclosporine is due to limb bud cell toxicity rather than inhibition of cell differentiation.
Botha, Erika; Erasmus, Rene; van Deventer, Martie
The mere fact that a library service is being used does not mean that the service makes a difference or has a positive impact on the user. This has significant implications for Special Library and Information Services (SL&IS) that have to constantly prove that they add value. Because of the difficulty of measuring impact effectively, the…
Linderman, Richard W; Linderman, Mark H; Lin, Chun-Shin
.... However, this paper reports on the ability of FPGAs to greatly accelerate non-numerical applications, particularly fundamental operations supporting publish subscribe information management environments...
Romanenko, A.G.; Todeschini, C.
Development of the bibliographic data base covering the world-wide nuclear science literature is described along with the network arrangements by which the data base and associated services are made available. The consequences of the system's decentralized operating philosophy are also addressed. (U.K.)
This study investigated users satisfaction on the use of electronic information resources and services in MTN Net libraries in ABU & UNIBEN. Two objectives and one null hypotheses were formulated and tested with respect to the users' satisfaction on electronic information resources and services in MTN Net libraries in ...
... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false Auditing Transmission Service Information. 37.7 Section 37.7 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY... SYSTEMS § 37.7 Auditing Transmission Service Information. (a) All OASIS database transactions, except...
Many rural communities have continued to be underserved; hence, information becomes necessary in integrating the needs of the people for sustainable development. Librarians and libraries are charged with providing the information resources and outreaches to the communities to help build the bridge between the ...
Zunilka Limonta Favier
Full Text Available We present a service that enables the design, management, innovation and implementation of information systems in academic, service, economic etc. which is intended as advice to entities that require attending to their needs whether external or internal. They offer some recommendations to improve the work in information systems and management. This paper shows how to provide differentiated services according to the characteristics of each institution.
Rogge, C.B.E.; Becker, Tilman C.
In order to define consumer expectations over a traceability and information system for the entire food supply chain, the information behaviour of consumers in the food service industry has been subject to an analysis for the first time. In comparison to consumers in retailing, significant differences appear in information seeking behaviour as well as in the information desired.
For the majority of poor people in developing countries, informal insurance provides an important - and often the only - way of protecting themselves against the risk of sickness or the death of a family member. At the same time, informal insurance provides a vital source of livelihood for many. In South Africa, the ...
Smith, Warren; Waheed, Abdul; Meyers, David; Yan, Jerry; Kwak, Dochan (Technical Monitor)
The Globus information service wasn't working well. There were many updates of data from Globus daemons which saturated the single server and users couldn't retrieve information. We created a second server for NASA and Alliance. Things were great on that server, but a bit slow on the other server. We needed to know exactly how the information service was being used. What were the best servers and configurations? This viewgraph presentation gives an overview of the evaluation of alternative designs for a Grid Information Service. Details are given on the workload characterization, methodology used, and the performance evaluation.
Lamont, Harriet F; Blogg, Henrietta J; Lamont, Ronald F
The extent of antibiotic use in pregnancy remains unknown but may occur in > 40% of pregnant women for various indications, at different gestational ages from different sources. Antibiotic resistance, alterations to the neonatal immune system causing allergy, asthma and atopic disease in later life and teratogenicity. Although teratogenesis is not a major concern, it is important, and ignorance and complacency cast a long shadow. Robust evidence exists to guide clinicians in their choice of a safe agent with respect to teratogenicity. Antibiotic resistance is a major safety concern, and together with decreased research and development of new antibiotic agents, it has required legal initiatives to encourage Big Pharma to search for safe alternatives. New information from culture-independent, molecular-based techniques has resulted in a greater understanding of the adverse effects of antepartum/intrapartum antibiotics on the maternal vaginal microbiome and the neonatal gut microbiome. As this might adversely affect the development of the immature immune system and lead to asthma, allergy and atopic disease in later life, new research merits support in scrutinizing the safety of antibiotic use in pregnancy.
Full Text Available Purpose of the research is to ensure the securities of information system asset and to ensure if informa-tion system support the operational and data collected was valid. Research method that used in this research were library studies and field studies. Field studies such an observation, questioner, and inter-view. the expected result are founding the weakness of security management control, operational man-agement control, input control, and output control of risk happened in the company. Conclusion of this research are the system on the company work good and there’s no potential risk happened and make an impact to the delivery process of information system.Index Terms - Auditing Information system, Delivery product process.
Full Text Available This paper argues that most banks have failed to exploit the potential of self-service banking because they base their service design on an incomplete business model for self-service. A framework for evaluation of self-service banking concepts is developed on the basis of Stabell and Fjeldstad's three value configurations. The value network and the value shop are consistent with self-service banking while the value chain is inappropriate. The impact of the value configurations on information exchange and self-service functionality is discussed, and a framework for design of such services proposed. Current self-service banking practices are compared to the framework, and it is concluded that current practice matches the concept of a value network and not the value shop. However, current practices are only a partial implementation of a value network-based self-service banking concept.
MARIA MALLIAROU & SOFIA ZYGA
Full Text Available Nursing Information System (NIS has been defined as “a part of a health care information system that deals with nursing aspects, particularly the maintenance of the nursing record”. Nursing Uses of Information Systems in order to assess patient acuity and condition, prepare a plan of care or critical pathway, specify interventions, document care, track outcomes and control quality in the given patient care. Patient care processes, Communication, research, education and ward management can be easily delivered using NIS. There is a specific procedure that should be followed when implementing NISs. The electronic databases CINAHL and Medline were used to identify studies for review. Studies were selected from a search that included the terms ‘nursing information systems’, ‘clinical information systems’, ‘hospital information systems’, ‘documentation’, ‘nursing records’, combined with ‘electronic’ and ‘computer’. Journal articles, research papers, and systematic reviews from 1980 to 2007 were included. In Greek Hospitals there have been made many trials and efforts in order to develop electronic nursing documentation with little results. There are many difficulties and some of them are different levels of nursing education, low nurse to patient ratios, not involvement of nurses in the phases of their implementation, resistance in change. Today’s nursing practice in Greece needs to follow others counties paradigm and phase its controversies and problems in order to follow the worldwide changes in delivering nursing care.
This will put pressure on informal businesses to enter the regulated system. ... understanding of the impact of formalization on the funeral parlour industry. ... in support of the growth and development of small funeral parlour businesses.
Full Text Available Service matching aims to find the information similar to a given query, which has numerous applications in web search. Although existing methods yield promising results, they are not applicable for transportation. In this paper, we propose a multilevel matching method based on semantic technology, towards efficiently searching the traffic information requested. Our approach is divided into two stages: service clustering, which prunes candidate services that are not promising, and functional matching. The similarity at function level between services is computed by grouping the connections between the services into inheritance and noninheritance relationships. We also developed a three-layer framework with a semantic similarity measure that requires less time and space cost than existing method since the scale of candidate services is significantly smaller than the whole transportation network. The OWL_TC4 based service set was used to verify the proposed approach. The accuracy of offline service clustering reached 93.80%, and it reduced the response time to 651 ms when the total number of candidate services was 1000. Moreover, given the different thresholds for the semantic similarity measure, the proposed mixed matching model did better in terms of recall and precision (i.e., up to 72.7% and 80%, respectively, for more than 1000 services compared to the compared models based on information theory and taxonomic distance. These experimental results confirmed the effectiveness and validity of service matching for responding quickly and accurately to user queries.
Dynamic chaining of geographic information services (geo-services) is gaining popularity as a new paradigm for evolving flexible geo-information systems and for providing on-demand access to geo-information. In dynamic chaining, disparate geo-services are discovered and composed at run time to yield more elaborate functionality and create value-added geo-information. Common approaches to service chaining discover and compose disparate geo-services based on the functional capability of individual geo-services. The primary concern of common approaches is thus the emergent behavior of the resulting composite geo-service. However, as geo-services become mundane and take on a greater and more strategic role in mission critical processes, deliverable quality of service (QoS) becomes an important concern. QoS concerns operational characteristics of a service that determine its utility in an application context. To address pertinent QoS requirements, a new approach to service chaining becomes necessary. In this paper we propose a QoS-aware chaining approach in which geo-services are discovered, composed and executed considering both functional and QoS requirements. We prescribe a QoS management framework that defines fundamental principles, concepts and mechanisms which can be applied to evolve an effective distributed computing platform for QoS-aware chaining of geo-services - the so-called geo-service infrastructure. The paper also defines an extensible QoS model for services delivered by dynamic compositions of geo-services. The process of orthophoto generation is used to demonstrate the applicability of the prescribed framework to service-oriented geographic information processing.
Do It Now Foundation, Phoenix, AZ.
This compilation of journal articles provides basic information on abuse of Talwin, a mild prescription painkiller (T's), and Pyribenzamine, a nonprescription antihistimine (Blues). These two drugs, taken in combination, produce an effect similar to that produced by heroin. Stories from "Drug Survival News,""Emergency…
Full Text Available Objectives – The purpose of this research project was to gain insight into the information behaviour of healthcare services managers as they use information while engaged in decision-making unrelated to individual patient care. Methods – This small-scale, exploratory, multiple case study used the critical incident technique in nineteen semi-structured interviews. Responses were analyzed using ‘Framework,’ a matrix-based content analysis system. Results – This paper presents findings related to the internal information that healthcare services managers need and use. Their decisions are influenced by a wide variety of factors. They must often make decisions without all of the information they would prefer to have. Internal information and practical experience set the context for new research-based information, so they are generally considered first.Conclusions – Healthcare services managers support decisions with both facts and value-based information. These results may inform both delivery of health library services delivery and strategic health information management planning. They may also support librarians who extend their skills beyond managing library collections and teaching published information retrieval skills, to managing internal and external information, teaching information literacy, and supporting information sharing.
subscribed to weekly MARC tapes of British and American literature, and each tape was run on the AWRE computer, against a stored profile of Dewey Decimal ...are made, and local information, eg, call number, is added. The books are also indexed by the Universal Decimal Classification (UDC). A further update...Classification ( DDC ) numbers. A printout of the selected records was used as a book selection tool, whilst AMCOS stored these records in a cumulating
Full Text Available Information system change is concerned with deliberate modifications to an organization’s technical and organiza‐ tional subsystems that deal with information. Changes result in adjustments being made to the configuration of information systems that could have an impact on the operations of those systems. This paper examines the problem of interference between old configuration activi‐ ties, new configuration activities and reconfiguration activities that occur due to overlapping modes. The paper proposes a novel form of depicting and solving the problem based on a flow-based conceptualization in which a configuration can be viewed as a system of flow systems organized architecturally, described by their internal flows, and connected by external flows and triggering. This method of diagramming is applied to a complex case study involving the reconfiguration of an office workflow for order processing described in BPMN. The diagrams resulting from this method and the BPMN diagrams are then examined side by side. Accordingly, the conclusion is that a new high-level representation seems more system‐ atic as a foundation for building a conceptual schema of business processes.
Dwisari Dillasamola; Almahdy A; Amirah Desri; Skunda Diliarosta
Yogurt is one of the dairy products made from lactic acid fermentation by using Lactobacillus bulgaricus and Streptococcus thermophilus. A study on teratogenic effects of yogurt on the white female mice fetus (Mus musculus) has been carried out. Pregnant mice used were 20 which divided into 4 groups : the control group, D1, D2, and D3. The treatments giveThe mice were Distidelled water (control), 0.52 yogurt (D1), 1.04 yogurt (D2), and 2.08 g yogurt (D3). Data were analyzed using one-way ANO...
Full Text Available The goal of the article is to determine the place and role of opinion giving services in consumer behaviours. The discussion is conducted around the thesis saying that in the information society, opinion giving services constitute an important source of information for consumers in the process of selecting and purchasing both products and services. In the article the research approach based on the theoretical and empirical examinations was presented. The discussion starts with presenting a defi nition and types of opinion giving services which constitute the base for the characteristics of activities and usefulness of web portals collecting consumers opinions. The use of opinion giving services provided in the purchase process was evaluated. An essential interest in other consumers opinions, placed in Internet, was observed together with perceiving them as credible. Positive assessment of the functionality of opinion giving services was noticed.
... DEPARTMENT OF THE TREASURY Fiscal Service Financial Management Service; Proposed Collection of Information: Assignment Form AGENCY: Financial Management Service, Fiscal Service, Treasury. ACTION: Notice... Management Service, Records and Information Management Branch, Room 135, 3700 East West Highway, Hyattsville...
Garmann-Johnsen, Niels Frederik; Mettler, Tobias; Sprenger, Michaela
Recent advances in electronics and telecommunication have paved the way for service robots to enter the clinical world. While service robotics has long been a core research theme in computer science and other engineering-related fields, it has attracted little interest of Information Systems (IS) researchers so far. We argue that service robotics represents an interesting area of investigation, especially for healthcare, since current research lacks a thorough examination of socio-technical p...
Webb, R. S.; Pulwarty, R. S.; Davidson, M. A.; Shea, E. E.; Nierenberg, C.; Dole, R. M.
Climate variability and change impact national and local economies and environments. Developing and communicating climate and climate impacts information to inform decision making requires an understanding of context, societal objectives, and identification of factors important to the management of risk. Information sensitive to changing baselines or extremes is a critical emergent need. Meeting this need requires timely production and delivery of useful climate data, information and knowledge within familiar pathways. We identify key attributes for a climate service , and the network and infrastructure to develop and coordinate the resulting services based on lessons learned in experimental implementations of climate services. "Service-type" activities already exist in many settings within federal, state, academic, and private sectors. The challenge for a climate service is to find effective implementation strategies for improving decision quality (not just meeting user needs). These strategies include upfront infrastructure investments, learning from event to event, coordinated innovation and diffusion, and highlighting common adaptation interests. Common to these strategies is the production of reliable and accessible data, analyses of emergent conditions and needs, and deliberative processes to identify appropriate entry points and uses for improved knowledge. Experimental climate services show that the development of well-structured paths among observations, projections, risk assessments and usable information requires sustained participation in “knowledge management systems” for early warning across temporal and spatial scales. Central to these systems is a collaborative framework between research and management to ensure anticipatory coordination between decision makers and information providers, allowing for emerging research findings and their attendant uncertainties to be considered. Early warnings in this context are not simply forecasts or
Marketing Strategy: A Tool for Library and Information Services Delivery by ... delivery by academic libraries using the various technology driven facilities. ... Data were gathered using questionnaire and the findings revealed that face to face ...
Adaptive technologies for library and information services for physically challenged in special education schools of Kaduna State. ... special education schools because; these are genuine demand from adaptive technology users of the library.
National Aeronautics and Space Administration — The NASA Goddard Earth Sciences (GES) Data and Information Services Center (DISC) is the home (archive) of Precipitation, Atmospheric Chemistry and Dynamics, and...
Giesbers, Bas; Taddeo, Antonio; Van der Vegt, Wim; Van Bruggen, Jan; Koper, Rob
Giesbers, B., Taddeo, A., van der Vegt, W., van Bruggen, J., Koper, R. (2007). A Question Answering service for information retrieval in Cooper. Paper presented at the Cooper workshop, September 18, Crete, Greece.
... lands, we issue permits for commercial guide services, including big game hunting, sport fishing... information during the competitive selection process for big game and sport fishing guide permits to evaluate...
National Oceanic and Atmospheric Administration, Department of Commerce — National Weather Service (NWS) Station Information System (SIS) contains observing station metadata from November 2016 to present. These are renditions are used for...
The purpose of this study is to determine the attitude of in-service science teachers towards information communication technology (ICT) in education. The study explores the relationship between in-service teachers and four independent variables: their attitudes toward computers; their cultural perception of computers; their perceived computer…
Klobas, Jane E.
Examines factors to be considered in the management of technological change in libraries and information services. The organizational climate for change is discussed, and factors to consider when developing a strategy for introducing a new product, service, or system are described, including leadership, goals, political processes, marketing, and…
Woy, James B.
Reports results of 1983 survey of 25 public libraries and 1981 survey of 11 public libraries, both of which focused on facets of online information services--user fees, databases, documentation, equipment, miscellaneous services, and subject areas searched. The 1983 questionnaire and seven sources are appended. (EJS)
Discusses criteria for evaluating school library information services. Highlights include types of services; physical facilities; library usage; circulation statistics; changes due to technology; fill rate, or the percentage of successful searches for library materials; OPAC (online public access catalog) reports; observation; and examining…
Full Text Available The Information Service is a fundamental component in a grid environment. It has to meet a lot of requirements such as access to static and dynamic information related to grid resources, efficient and secure access to dynamic data, decentralized maintenance, fault tolerance etc., in order to achieve better performance, scalability, security and extensibility. Currently there are two different major approaches. One is based on a directory infrastructure and another one on a novel approach that exploits a relational DBMS. In this paper we present a performance comparison analysis between Grid Resource Information Service (GRIS and Local Dynamic Grid Catalog relational information service (LDGC, providing also information about two projects (iGrid and Grid Relational Catalog in the grid data management area.
Leonardo Bastos Pontes
Full Text Available This paper is held in the information technology services management environment, with a few ideas of information technology governance, and purposes to implement a hybrid model to manage the services of a database, based on the principles of information technology services management in a supplementary health operator. This approach utilizes fundamental nuances of services management guides, such as CMMI for Services, COBIT, ISO 20000, ITIL and MPS.BR for Services; it studies harmonically Availability and Continuity Management, as most part of the guides also do. This work has its importance because it keeps a good flow in the database and improves the agility of the systems in the accredited clinics in the health plan.
Full Text Available Abstract Congenital anomalies are already the second cause of infant mortality in Brazil, as in many other middle-income countries in Latin America. Birth defects are a result of both genetic and environmental factors, but a multifactorial etiology has been more frequently observed. Here, we address the environmental causes of birth defects – or teratogens – as a public health issue and present their mechanisms of action, categories and their respective maternal-fetal deleterious effects. We also present a survey from 2008 to 2013 of Brazilian cases involving congenital anomalies (annual average of 20,205, fetal deaths (annual average of 1,530, infant hospitalizations (annual average of 82,452, number of deaths of hospitalized infants (annual average of 2,175, and the average cost of hospitalizations (annual cost of $7,758. Moreover, we report on Brazilian cases of teratogenesis due to the recent Zika virus infection, and to the use of misoprostol, thalidomide, alcohol and illicit drugs. Special attention has been given to the Zika virus infection, now proven to be responsible for the microcephaly outbreak in Brazil, with 8,039 cases under investigation (from October 2015 to June 2016. From those cases, 1,616 were confirmed and 324 deaths occurred due to microcephaly complications or alterations on the central nervous system. Congenital anomalies impact life quality and raise costs in specialized care, justifying the classification of teratogens as a public health issue.
Full Text Available Yogurt is one of the dairy products made from lactic acid fermentation by using Lactobacillus bulgaricus and Streptococcus thermophilus. A study on teratogenic effects of yogurt on the white female mice fetus (Mus musculus has been carried out. Pregnant mice used were 20 which divided into 4 groups : the control group, D1, D2, and D3. The treatments giveThe mice were Distidelled water (control, 0.52 yogurt (D1, 1.04 yogurt (D2, and 2.08 g yogurt (D3. Data were analyzed using one-way ANOVA followed by Duncan multiple range test. Results showed that administration of yogurt during pregnancy could affect mother body weight of mice (P 0,05. Observations with Alizarin solution did not show skeletal defects in comparison to the control group. Observations with Bouin’s solution showed defective visceral cleft palate in fetal mice yogurt group D3. This study conclude that yogurt is safe to consume in groups D1 and D2. Yogurt has the potential to cause fetal teratogenic in group D3
Inouye, Minoru; Kajiwara, Yuji
Pregnant mice were given p.o. various nonteratogenic doses (0, 2.5 and 10 mg/kg) of methylmercuric chloride on day 9 of pregnancy, and then injected i.p. with a teratogenic dose (4 mg/kg) of mitomycin-C on day 10. Major malformations produced by mitomycin-C alone were cervical rib and vertebral anomaly, polydactyly of the hindlimb and tail anomaly. Combined treatment significantly increased the incidence of these malformations, showing the dose-effect relationship of methylmercury, whereas methylmercury alone is known not to produce such malformations. When mitomycin-C treatment alone was performed on day 9.5 of pregnancy, only vertebral anomalies increased in incidence. Therefore, mitomycin-C teratogenicity in terms of the manifestation of cervical rib, polydactyly and tail anomaly, but not vertebral anomaly, was suggested to be enhanced by methylmercury. A considerable number of foetuses showed cleft palate involvement following combined treatments, but not by either chemical alone. Cleft palate is known to be a major malformation in mice that is caused by methylmercury, and mitomycin-C also induces cleft palate. Therefore, the two chemicals might have affected foetuses additively and thereby induced cleft palate. (orig.)
Satow, Yukio; Lee, Juing-Yi; Hori, Hiroshi; Okuda, Hiroe; Tsuchimoto, Shigeo; Sawada, Shozo; Yokoro, Kenjiro
The teratogenicity of Californium-252 (Cf-252) irradiation which generates approximately 70% 2.3 MeV fast neutron and 30% gamma rays was evaluated. A single whole body exposure of Cf-252 at various doses was given to pregnant rats on day 8 or 9 of pregnancy, followed by microscopic autopsy of the fetuses at the terminal stage of pregnancy to search for external and internal malformations. For comparison, pregnant rats were irradiated with various doses of Cobalt-60 (Co-60) standard gamma rays at the same dose rate (1 rad/min.). The doses were 20-120 rad of Cf-252 and 80-220 rad of Co-60. Using frequency of radiation induced malformations observed on day 8 of pregnancy as an index, relative biological effectiveness (RBE) of 2.3-2.7 was obtained from the straight line obtained by modifying by the least squares method the frequency curves of malformed fetuses in total implants and in surviving fetuses. The types of malformations induced by Cf-252 and Co-60 irradiation were alike. Using fetal LD 50 as an index, 2.4 was obtained as RBE when irradiated on day 8 of pregnancy and 3.1 as that when irradiated on day 9. The results showed that Cf-252 had stronger a teratogenic effect than Co-60 gamma rays. (author)
Green, Benedict T; Lee, Stephen T; Panter, Kip E; Welch, Kevin D; Cook, Daniel; Pfister, James A; Kem, William R
Teratogenic alkaloids are found in many species of plants including Conium maculatum L., Nicotiana glauca, Nicotiana tabaccum, and multiple Lupinus spp. Fetal musculoskeletal defects produced by alkaloids from these plants include arthrogyropisis, scoliosis, torticollis, kyposis, lordosis, and cleft palate. A pharmacodynamic comparison of the alkaloids ammodendrine, anabasine, anabaseine, anagyrine, and coniine in SH-SY5Y cells and TE-671 cells was made. These alkaloids and their enantiomers were more effective in depolarizing TE-671 cells which express the human fetal-muscle type nicotinic acetylcholine receptor (nAChR) relative to SH-SY5Y cells which predominately express autonomic nAChRs. The rank order of potency in TE-671 cells was: anabaseine>(+)-anabasine>(-)-anabasine > (+/-)-anabasine>anagyrine>(-)-coniine > (+/-)-coniine>(+)-coniine>(+/-)-ammodendrine>(+)-ammodendrine. The rank order potency in SH-SY5Y cells was: anabaseine>(+)-anabasine>(-)-coniine>(+)-coniine>(+)-ammodendrine>anagyrine>(-)-anabasine>(+/-)-coniine>(+/-)-anabasine>(-)-ammodendrine. The actions of these alkaloids at nAChRs in both cell lines could be distinguished by their maximum effects in depolarizing cell membrane potential. The teratogenic action of these compounds may be related to their ability to activate and subsequently desensitize nAChRs.
Mazzu-Nascimento, Thiago; Melo, Débora Gusmão; Morbioli, Giorgio Gianini; Carrilho, Emanuel; Vianna, Fernanda Sales Luiz; da Silva, André Anjos; Schuler-Faccini, Lavinia
Abstract Congenital anomalies are already the second cause of infant mortality in Brazil, as in many other middle-income countries in Latin America. Birth defects are a result of both genetic and environmental factors, but a multifactorial etiology has been more frequently observed. Here, we address the environmental causes of birth defects – or teratogens – as a public health issue and present their mechanisms of action, categories and their respective maternal-fetal deleterious effects. We also present a survey from 2008 to 2013 of Brazilian cases involving congenital anomalies (annual average of 20,205), fetal deaths (annual average of 1,530), infant hospitalizations (annual average of 82,452), number of deaths of hospitalized infants (annual average of 2,175), and the average cost of hospitalizations (annual cost of $7,758). Moreover, we report on Brazilian cases of teratogenesis due to the recent Zika virus infection, and to the use of misoprostol, thalidomide, alcohol and illicit drugs. Special attention has been given to the Zika virus infection, now proven to be responsible for the microcephaly outbreak in Brazil, with 8,039 cases under investigation (from October 2015 to June 2016). From those cases, 1,616 were confirmed and 324 deaths occurred due to microcephaly complications or alterations on the central nervous system. Congenital anomalies impact life quality and raise costs in specialized care, justifying the classification of teratogens as a public health issue. PMID:28534929
Mercury is a major environmental pollutant and a proven teratogen in man and animals. Its teratogenicity and effects on fetal chromosomes were investigated in mice. Various dose levels of methylmercuric chloride (MMC) 1000 ppm (5 mg through 30 mg/kg of body weight) were administered via an intragastric tube to pregnant ICR Swiss/Webster mice on day 9 of gestation. On day 18 of gestation the animals were killed and the fetuses removed. Fetal lung and liver section were processed for light microscopy, electron microscopy and cytogenetic studies. Mercury levels were determined in maternal blood and randomly selected fetuses. A significant increase in embryonic deaths and resorptions were observed at all dose levels. Light microscopy of fetal lungs from MMC treated animals were hypoplastic and retarded in development. The severity of pulmonary changes increased with the dose-level of MMC. Electron microscopy of fetal lung and liver showed degeneration of mitochondria. Vacuolation and lysis of mitochondria increased in severity with the dose-level of MMC. The frequency of sister chromatid exchangers (SCEs) increased significantly as the dosage increased. The frequency of nucleolus organizing regions (NORs) per cell did not change significantly between the treatment groups and the control. Clumping of chromosomes was prevalent and may be due to deactivation of the microtubular proteins following mercury binding.
Mas, A.; Holt, D.; Webb, M.
The increased susceptibility of the pregnant rat to intraperitoneally administered nickel (Ni) is apparent at 12 and 19 days of pregnancy and cannot be due, therefore, to the increase in total body weight. Teratogenic malformations occur when Ni is administered during organogenesis and are maximal at dose levels that are toxic for the dam. The yolk sac and chorioallantoic placentas accumulate Ni, but this does not prevent the transport of the metal to the embryo or foetus. The Ni concentrations in the conceptuses decrease more slowly with time than those in the maternal organs. In the foetuses, the decrease in concentration is due to the increase in weight, since the content of Ni increases between 4 h and 24 h. Foetal uptake of ( 14 C)thymidine, ( 3 H)leucine and 65 Zn is unaffected at 3 h after the injection of the dam with 4 mg Ni/kg body wt. Incorporation of ( 3 H)leucine into foetal protein, but not the incorporation of ( 14 C)thymidine into DNA, is decreased at this time. A major effect of treatment with this teratogenic dose is an increase in the maternal plasma glucose concentration which, in turn, alters the supply of the sugar to the foetus. The possible relevance of temporary foetal hyperglycaemia to teratogenesis is discussed. (author)
At the request of the Government of Peru an IAEA staff member undertook an expert assignment to the Instituto Peruano de Energia Nuclear (IPEN) within the framework of a technical assistance project. The purpose of the expert's travel was to evaluate a request for equipment for and consultant's advice on the establishment of library and information services and to advise IPEN staff on the establishment of the services. The report presents the findings on the present level and future need for library and information services and presents a proposal for the further development of these. (author)
Bevinakoppa, S.; Ferreira Pires, Luis; Hammoudi, S.
Web services and Model-driven development are two emerging research fields and have been receiving a lot of attention in the recent years. New approaches on these two areas can bring many benefits to the development of information systems, distribution flexibility, interoperability, maintainability
Li, Heyuan; Li, Yongxing; Xue, Zhiyong; Feng, Tao
With the development of geographical information service technologies, how to achieve the intelligent scheduling and high concurrent access of geographical information service resources based on load balancing is a focal point of current study. This paper presents an algorithm of dynamic load balancing. In the algorithm, types of geographical information service are matched with the corresponding server group, then the RED algorithm is combined with the method of double threshold effectively to judge the load state of serve node, finally the service is scheduled based on weighted probabilistic in a certain period. At the last, an experiment system is built based on cluster server, which proves the effectiveness of the method presented in this paper.
van Gelder, Marleen M. H. J.; de Jong-van den Berg, Lolkje T. W.; Roeleveld, Nel
What is the current state of knowledge on the human risks of drugs suspected to be associated with teratogenic mechanisms? Evidence for the presence or absence of human risks of birth defects is scarce or non-existent for the majority of drugs associated with teratogenic mechanisms. Medical drugs
Horak, J.; Orlik, A.; Stromsky, J.
Web services support the integration and interoperability of Web-based applications and enable machine-to-machine interaction. The concepts of web services and open distributed architecture were applied to the development of T-DSS, the prototype customised for web based hydro-information systems. T-DSS provides mapping services, database related services and access to remote components, with special emphasis placed on the output flexibility (e.g. multilingualism), where SOAP web services are mainly used for communication. The remote components are represented above all by remote data and mapping services (e.g. meteorological predictions), modelling and analytical systems (currently HEC-HMS, MODFLOW and additional utilities), which support decision making in water management.
Knowledge preservation, access to information and dissemination has rapidly changed the way people seek and use information. The study concluded that the application of IT will encourage self sufficiency in food production, good health and rapid development among the citizenry. Keywords: Library service delivery, ...
Library and information services: the need for their promotion in Ogun state, Nigeria. WO Lawal, OI Amusa. Abstract. No Abstract. Lagos Journal of Library and Information Science Vol. 3(1) 2005: 32-42. Full Text: EMAIL FULL TEXT EMAIL FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT.
Gupta, Dinesh K; Massisimo, Angels
With contributions from library and information professionals (practitioners, researchers, faculty members, consultants, and others), Marketing Library and Information Services: A Global Outlook highlights a variety of exemplary LIS marketing practices and efforts from around the globe. The following broad topics are explored: changing marketing concepts; marketing library
... of providing current information but personalized to the faculty, and keeps them abreast of the latest development. One of the major challenges of the operations in RUN is that certain search engines being used in the provision of SDI services e.g yahoo and AltaVista are not good enough for effective information retrieval.
In recent years, China has developed modern agriculture energetically. An effective information framework is an important way to provide farms with agricultural information services and improve farmer's production technology and their income. The mountain areas in central China are dominated by agri...
..., research centers, and individual members of the medical profession, under which medical information and techniques will be freely exchanged and the medical information services of all parties to the agreement will... highly trained and qualified members of the medical profession. (c) Use of electronic equipment. Recent...
Ping; JIA; Yajing; LIU; Xiwen; LIU; Yu; DENG; Yue; YOU; Su; WANG; Xiaohua; PENG
Purpose: This study explores new content, forms, and fields of science and technology(S&T;) innovation and entrepreneurship information services of the National Science Library of the Chinese Academy of Sciences(NSLC).Design/methodology/approach: We cooperated with incubator enterprises and set up an "S&T; Innovation and Entrepreneurship Information Service Platform." We designed five series of activities, including industrial information release, project financing and roadshows, entrepreneurial sharing, entrepreneurial coaching sessions, and entrepreneurial salons. Based on the implementation of these activities, we designed new NSLC library services for S&T; innovation and entrepreneurship.Findings: Since the construction of the platform, these five series of activities have attracted more than 80 business projects, 90 investors, and 30 researchers. Furthermore, more than 20 media representatives and nearly 300 entrepreneurs have participated in the activities that the NSLC has organized in the past two years. Through these activities, we have defined an S&T; innovation and entrepreneurship knowledge service model for the NSLC.Research limitations: The service practice of the NSLC is still in the demonstration phase. Due to staffing limitations of our service teams, the expansion of our service activities has been greatly restricted.Practical implications: The innovation and entrepreneurship information services of the NSLC provide a lot of material for transformation of library services for domestic and foreign special libraries.Originality/value: It is useful to transform library and business services by embedding them into ways in which we serve innovation and entrepreneurial activities. This opens up a new field of library knowledge services in China.
Lu, Xiaodong; Mori, Kinji
The market and users' requirements have been rapidly changing and diversified. Under these heterogeneous and dynamic situations, not only the system structure itself, but also the accessible information services would be changed constantly. To cope with the continuously changing conditions of service provision and utilization, Faded Information Field (FIF) has been proposed, which is a agent-based distributed information service system architecture. In the case of a mono-service request, the system is designed to improve users' access time and preserve load balancing through the information structure. However, with interdependent requests of multi-service increasing, adaptability and timeliness have to be assured by the system. In this paper, the relationship that exists among the correlated services and the users' preferences for separate and integrated services is clarified. Based on these factors, the autonomous preference-aware information services integration technology to provide one-stop service for users multi-service requests is proposed. As compared to the conventional system, we show that proposed technology is able to reduce the total access time.
Full Text Available This study presents a cloud service customized product information system to enable businesses to provide customized product marketing on the Internet to meet consumer demand for customized products. The cloud service of the information system development strategic framework proposed in this study contains three elements: (1 e-commerce services, (2 promotion type modules, and (3 cloud services customized promotional products. In this study, a mining cloud information system to detect customer behavior is proposed. The association rules from relational database design are utilized to mine consumer behavior to generate cross-selling proposals for customer products and marketing for a retailing mall in Taiwan. The study is composed of several parts, as follows. A market segment and application of association rules in data exploration techniques (Association Rule Mining and sequence-like exploration (Sequential Pattern Mining, efficient analysis of customers, consumer behavior, identification of candidates for promotional products, and using cloud service delivery and evaluation of targets to evaluate candidates for promotional products for production. However, in addition to cloud service customized promotional products, the quantity of promotional products sales varies for different customers. We strive to achieve increased customer loyalty and profits through the use of active cloud service customized promotional products.
Seok-Hyoung Lee; Hwan-Min Kim; Ho-Seop Choe
Through a series of precise text handling processes, including automatic extraction of information from documents with knowledge from various fields, recognition of entity names, detection of core topics, analysis of the relations between the extracted information and topics, and automatic inference of new knowledge, the most efficient knowledge base of the relevant field is created, and plans to apply these to the information knowledge management and service are the core requirements necessa...
Tuomainen, Mika; Mykkänen, Juha
Personal information management has been proposed as an important enabler for individual empowerment concerning citizens' wellbeing and health information. In the MyWellbeing project in Finland, a strictly citizen-driven concept of "Coper" and related architectural and functional guidelines have been specified. We present a reference architecture and a set of identified application services to support personal wellbeing information management. In addition, the related standards and developments are discussed.
Kostagiolas, P.; Lappa, E.
Information is at the centre of every hospital activity including clinical decisions and healthcare service delivery systems. Although information is an important hospital asset, several issues related to its management and organization needs to be addressed within the hospitals. The management of healthcare information is a strategic goal related to the reduction of healthcare service provision costs, and to the improvement of quality and safety of healthcare services. By discussing the rather obvious necessity for information organization and management in the healthcare domain, this work aims at the role of healthcare information services, i.e. hospital libraries and patient medical records. Finally, a typology of information services' contributions to hospital environment is presented.
Webb, M.; Holt, D.; Brown, N.; Hard, G.C.
A single dose in the range 0.25-1.9 mg metallothionein-bound cadmium (MT-Cd)/kg body weight, when administered parenterally to the rat between day 8 and day 14 of gestation, is teratogenic. In vitro, the development of the isolated rat conceptus is unaffected by the addition of 1.5 μM MT-Cd to the culture medium whereas the same concentration of ionic Cd (as CdCl 2 ) is lethal. At short times after injection of 0.25 mg MT-Cd/kg body weight on gd 12, the maximal foetal and placental contents of Cd are low in comparison with those after a teratogenic dose of CdCl 2 and are of the same order as those in the embryo and placenta + yolk sac of the rat conceptus, cultured in the presence of the highest no-effect concentration of CdCl 2 . From this evidence, it is concluded that the uptake by the conceptus in vivo of either CdMT, or of Cd liberated therefrom, is unlikely to contribute to the teratogenic response. In the pregnant, as in the non-pregnant rat, the kidney appears to be the only organ that is affected directly by the metalloprotein. All doses in the range 0.25-1.0 mg MT-Cd/kg body weight are nephrotoxic and result in prolonged anorexia in the pregnant animal. While some of the foetal deformities that occur in the CdMT-dosed animal seem to be direct consequences of the renal dysfunction, others apparently are secondary to the maternal anorexia. In rats that are injected i.p on gd 12 with 0.25 mg MT-Cd/kg renal uptake of Cd is slower, but the final concentration is higher than in animals that are given the same dose i.v. At this and the higher dose levels structural and/or functional damage to the kidneys also is greater in i.p.-, than in i.v.-dosed animals. The incidence of foetal malformations, however, is similar in the i.p. and i.v. groups and varies little over the dose range. (orig./MG)
A SURVEY BY QUESTIONNAIRE WAS MADE OF THE PROBLEM OF USER SERVICES AND EXTENSION SERVICES USED IN THE DISSEMINATION OF MATERIALS AND INFORMATION TO A SELECTED NUMBER OF INDUSTRIAL LIBRARIES. THE SURVEY RESULTED IN DATA CONCERNING STAFF SIZE, PROFESSIONAL-TO-CLERICAL RATIO, SIZE OF BOOK, DOCUMENT, PERIODICAL AND MICROFORM COLLECTIONS, LIBRARY…
Examines the trend in outsourcing information services and suggests it threatens the survival of corporate libraries. Topics include changes in the competitive corporate environment; characteristics of outsourceable services; managing change; redesigning the corporate librarian's role; and implications for redesigning corporate information…
Funding for Teratology Information Services has been an ongoing struggle over the 25 years of its existence. Traditional and novel funding mechanisms have been explored with varying success. The importance of providing teratology risk assessment and counseling to all women of reproductive age is now an established health care objective. Sufficient and stable funding for these services is essential. Copyright © 2012 Wiley Periodicals, Inc.
Bernt Krohn Solvang
Full Text Available The issue to be discussed in this article is to what extent does ICT create new challenges for the relationship between public service providers and users? It is important to recognize the concept of social capital because the concept is vital to the understanding of access to the information society and efficient functioning of government in its service to citizens. In this way we see social capital as a mediating “institution” between public authorities and the citizens (users.
Shi , Xiaohui; Chen , Tian’en
International audience; Information service technology is a bridge between user and information resource, also is the critical factor to weight the quality of information service. Focusing on the information service features of tea industry, the demand-driven and interaction of information service were emphasized in this paper. User and market as the major criterion for testing the quality of information service, the interactive information service mode based on the demand-driven was proposed...
Hospital information systems (HISs) are becoming more important and covering more parts in daily hospital operations as order-entry systems become popular and electronic charts are introduced. Thus, HISs today need to be able to provide necessary services for hospital operations for a 24-h day, 365 days a year. The provision of services discussed here does not simply mean the availability of computers, in which all that matters is that the computer is functioning. It means the provision of necessary information for hospital operations by the computer software, and we will call it the availability of software services. HISs these days are mostly client-server systems. To increase availability of software services in these systems, it is not enough to just use system structures that are highly reliable in existing host-centred systems. Four main components which support availability of software services are network systems, client computers, server computers, and application software. In this paper, we suggest how to structure these four components to provide the minimum requested software services even if a part of the system stops to function. The network system should be double-protected in stratus using Asynchronous Transfer Mode (ATM) as its base network. Client computers should be fat clients with as much application logic as possible, and reference information which do not require frequent updates (master files, for example) should be replicated in clients. It would be best if all server computers could be double-protected. However, if that is physically impossible, one database file should be made accessible by several server computers. Still, at least the basic patients' information and the latest clinical records should be double-protected physically. Application software should be tested carefully before introduction. Different versions of the application software should always be kept and managed in case the new version has problems. If a hospital
Schwanzer, Michael; Fensel, Anna
We investigate services giving users an adequate insight on his or her energy consumption habits in order to optimize it in the long run. The explored energy awareness services are addressed to inhabitants of smart homes, equipped with smart meters, advanced communication facilities, sensors and actuators. To analyze the potential of such services, a game at a social network Facebook has been designed and implemented, and the information about players' responses and interactions within the game environment has been collected and analyzed. The players have had their virtual home energy usage visualized in different ways, and had to optimize the energy consumption basing on their own perceptions of the consumption information. Evaluations reveal, in particular, that users are specifically responsive to information shown as a real-time graph and as costs in Euro, and are able to produce and share with each other policies for managing their smart home environments.
Holt, D.; Webb, M.
In rats of the present (re-derived) Wistar-Porton strain that are dosed either intravenously (i.v.), or intraperitoneally (i.p.) with Cd (1.25 mg/kg body weight) on day 12 of gestation (gd 12), foetal uptake of Cd is at least 6-fold greater than that reported in an earlier study (Webb and Samarawickrama 1981). Higher doses (1.5 and 2.0 mg/kg body weight) are lethal to the maternal animal when administered i.v., but not if given ip. The foetotoxicity of i.p. injected Cd, however, increases with the dose over the range 1.25-2.0 mg Cd/kg body weight. The teratogenic response, which is also wider than that observed previously, is maximal after the injection of 1.25 mg Cd/kg body weight i.v. on gd 10 and i.p. on gd 12. Whilst the incidences of hydrocephalus, urogenital abnormalities, cleft palate and other less common defects are similar after dosing by both routes, the incidence, range and severity of skeletal malformations are greater after i.p. than after i.v. administration of Cd on gd 12. This difference in response is unlikely to be explained by a difference in either foetal, or placental uptake of the metallic ion since, at 4 h after i.p. dosing, the foetal concentration of Cd is not significantly different from that after i.v. injection, whilst the placental concentration is about 33% less. It is suggested that damage to the maternal liver, which is more severe after the i.v. injection of the optimum dose, may be an additional factor that, in conjunction with the inhibition of transport in the placenta and biosynthetic processes in the embryo/foetus, contributes to the teratogenic effects of Cd in the pregnant rat.
Xue, Wu; Zhang, Yongsheng; Yu, Ying; Zhao, Ling
In disaster rescue, emergency response and other occasions, traditional aerial photogrammetry is difficult to meet real-time monitoring and dynamic tracking demands. To achieve the live service of video geo-information, a system is designed and realized—an unmanned helicopter equipped with video sensor, POS, and high-band radio. This paper briefly introduced the concept and design of the system. The workflow of video geo-information live service is listed. Related experiments and some products are shown. In the end, the conclusion and outlook is given.
Full Text Available All academic information on the web or elsewhere has its creator, that is, a subject who has created the information. The subject can be an individual, a group, or an institution, and can be a nation depending on the nature of the relevant information. Most information is composed of a title, an author, and contents. An essay which is under the academic information category has metadata including a title, an author, keyword, abstract, data about publication, place of publication, ISSN, and the like. A patent has metadata including the title, an applicant, an inventor, an attorney, IPC, number of application, and claims of the invention. Most web-based academic information services enable users to search the information by processing the meta-information. An important element is to search information by using the author field which corresponds to a personal name. This study suggests a method of efficient indexing and using the adjacent operation result ranking algorithm to which phrase search-based boosting elements are applied, and thus improving the accuracy of the search results of personal names. It also describes a method for providing the results of searching co-authors and related researchers in searching personal names. This method can be effectively applied to providing accurate and additional search results in the academic information services.
... DEPARTMENT OF THE TREASURY Fiscal Service Financial Management Service Proposed Collection of Information: Schedule of Excess Risks AGENCY: Financial Management Service, Fiscal Service, Treasury. ACTION: Notice and request for comments. SUMMARY: The Financial Management Service, as part of its continuing...
... DEPARTMENT OF THE TREASURY Fiscal Service Financial Management Service; Proposed Collection of Information: Pools and Associations--Annual Letter AGENCY: Financial Management Service, Fiscal Service, Treasury. ACTION: Notice and request for comments. SUMMARY: The Financial Management Service, as part of...
Libraries and librarians have been defined by the book throughout modern history. What happens when society increasingly lets print go in favour of storing, retrieving and manipulating electronic information? What happens after the book? After the Book explores how the academic library of the 21st Century is first and foremost a provider of electronic information services. Contemporary users expect today's library to provide information as quickly and efficiently as other online information resources. The book argues that librarians need to change what they know, how they work, and how they ar
... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-73,668] Swets Information Services, Operations Department, Information Technology Group, Marketing Group, Finance Group, Runnemede..., Information Technology (IT) Group, Marketing Group and the Finance Group into one entity instead of...
Kostagiolas, P., E-mail: email@example.com [Assistant Professor Department of Archives, Library Science and Museology, Ionian University, CORFU 49100 (Greece); Lappa, E., E-mail: firstname.lastname@example.org [Director of Medical Library of General Hospital Attikis KAT, Nikis 2 str, 14564 KIFFISIA-ATHENS (Greece)
Information is at the centre of every hospital activity including clinical decisions and healthcare service delivery systems. Although information is an important hospital asset, several issues related to its management and organization needs to be addressed within the hospitals. The management of healthcare information is a strategic goal related to the reduction of healthcare service provision costs, and to the improvement of quality and safety of healthcare services. By discussing the rather obvious necessity for information organization and management in the healthcare domain, this work aims at the role of healthcare information services, i.e. hospital libraries and patient medical records. Finally, a typology of information services’ contributions to hospital environment is presented.
Kostagiolas, P.; Lappa, E.
Information is at the centre of every hospital activity including clinical decisions and healthcare service delivery systems. Although information is an important hospital asset, several issues related to its management and organization needs to be addressed within the hospitals. The management of healthcare information is a strategic goal related to the reduction of healthcare service provision costs, and to the improvement of quality and safety of healthcare services. By discussing the rather obvious necessity for information organization and management in the healthcare domain, this work aims at the role of healthcare information services, i.e. hospital libraries and patient medical records. Finally, a typology of information services’ contributions to hospital environment is presented
Full Text Available The complexity of information is issued from interacting information sources (IS, and could be better exploited with respect to relevance of information. In distributed IS system, relevant information has a content that is in connection with other contents in information network, and is used for a certain purpose. The highlighting point of the proposed model is to contribute to information system agility according to a three-dimensional view involving the content, the use and the structure. This reflects the relevance of information complexity and effective methodologies through self organized principle to manage the complexity. This contribution is primarily focused on presenting some factors that lead and trigger for self organization in a Service Oriented Architecture (SOA and how it can be possible to integrate self organization mechanism in the same.
Full Text Available The internet provides a wide range of scientific information for different areas of research, used by the related scientific communities. Often the design or architecture of these web pages does not correspond to the mental model of their users. As a result the wanted information is difficult to find. Methods established by Usability Engineering and User Experience can help to increase the appeal of scientific internet information services by analyzing the users’ requirements. This paper describes a procedure to analyze and optimize scientific internet information services that can be accomplished with relatively low effort. It consists of a combination of methods that already have been successfully applied to practice: Personas, usability inspections, Online Questionnaire, Kano model and Web Analytics.
Hartshorne, J E; Carstens, I L
The purpose of this review is to establish a conceptual framework on the role of information systems in public health care. Information is indispensable for effective management and development of health services and therefore considered as an important operational asset or resource. A Health Information System is mainly required to support management and operations at four levels: namely transactional and functional; operational control; management planning and control; and strategic planning. To provide the necessary information needs of users at these levels of management in the health care system, a structured information system coupled with appropriate information technology is required. Adequate and relevant information is needed regarding population characteristics, resources available and expended, output and outcome of health care activities. Additionally information needs to be reliable, accurate, timely, easily accessible and presented in a compact and meaningful form. With a well-planned health information system health authorities would be in a position to provide a quality, cost-effective and efficient health service for as many people as need it, optimal utilisation of resources and to maintain and improve the community's health status.
Information development in Latin America has evolved, despite the costly economic, social and political adjustments carried out in most countries in the last two decades. New open market policies and technological developments has helped the region to increase their links with the rest of the world. Libraries can now use faster and more reliable telephone services and can acquire computer and network technology with less import barriers. Information demand is assumed to be greater in quali...
...] Notice of Request for Extension of Approval of an Information Collection; Veterinary Services; Customer... extension of approval of an information collection to evaluate service delivery by Veterinary Services to... INFORMATION CONTACT: For information on the Veterinary Services customer service survey, contact Ms. Pam Hart...
Chen, Li-Chin; Chen, Chi-Wen; Weng, Yung-Ching; Shang, Rung-Ji; Yu, Hui-Chu; Chung, Yufang; Lai, Feipei
Telehealthcare has been used to provide healthcare service, and information technology infrastructure appears to be essential while providing telehealthcare service. Insufficiencies have been identified, such as lack of integration, need of accommodation of diverse biometric sensors, and accessing diverse networks as different houses have varying facilities, which challenge the promotion of telehealthcare. This study designs an information technology framework to strengthen telehealthcare delivery. The proposed framework consists of a system architecture design and a network transmission design. The aim of the framework is to integrate data from existing information systems, to adopt medical informatics standards, to integrate diverse biometric sensors, and to provide different data transmission networks to support a patient's house network despite the facilities. The proposed framework has been evaluated with a case study of two telehealthcare programs, with and without the adoption of the framework. The proposed framework facilitates the functionality of the program and enables steady patient enrollments. The overall patient participations are increased, and the patient outcomes appear positive. The attitudes toward the service and self-improvement also are positive. The findings of this study add up to the construction of a telehealthcare system. Implementing the proposed framework further assists the functionality of the service and enhances the availability of the service and patient acceptances.
Manuel GÉRTRUDIX BARRIO
Full Text Available The combination of open data generated by government and the proliferation of mobile devices enables the creation of new information services and improved delivery of existing ones. Significantly, it allows citizens access to simple,quick and effective way to information. Free applications that use open data provide useful information in real time, tailored to the user experience and / or geographic location. This changes the concept of “service information”. Both the infomediary sector and citizens now have new models of production and dissemination of this type of information. From the theoretical contextualization of aspects such as processes datification of reality, mobile registration of everyday experience, or reinterpretation of the service information, we analyze the role of open data in the public sector in Spain and its application concrete in building apps based on this data sets. The findings indicate that this is a phenomenon that will continue to grow because these applications provide useful and efficient information to decision-making in everyday life.
Patterson, Brandon J; Bakken, Brianne K; Doucette, William R; Urmie, Julie M; McDonough, Randal P
The evolving health care system necessitates pharmacy organizations' adjustments by delivering new services and establishing inter-organizational relationships. One approach supporting pharmacy organizations in making changes may be informal learning by technicians, pharmacists, and pharmacy owners. Informal learning is characterized by a four-step cycle including intent to learn, action, feedback, and reflection. This framework helps explain individual and organizational factors that influence learning processes within an organization as well as the individual and organizational outcomes of those learning processes. A case study of an Iowa independent community pharmacy with years of experience in offering patient care services was made. Nine semi-structured interviews with pharmacy personnel revealed initial evidence in support of the informal learning model in practice. Future research could investigate more fully the informal learning model in delivery of patient care services in community pharmacies. Copyright Â© 2016 Elsevier Inc. All rights reserved.
Erwin, James; Eberline, Carl; Colquitt, Wanda
Today we are in the midst of information and 'total quality' revolutions. At the NASA STI Program's Center for AeroSpace Information (CASI), we are focused on using continuous improvements techniques to enrich today's services and products and to ensure that tomorrow's technology supports the TQM-based improvement of future STI program products and services. The Continuous Improvements Program at CASI is the foundation for Total Quality Management in products and services. The focus is customer-driven; its goal, to identify processes and procedures that can be improved and new technologies that can be integrated with the processes to gain efficiencies, provide effectiveness, and promote customer satisfaction. This Program seeks to establish quality through an iterative defect prevention approach that is based on the incorporation of standards and measurements into the processing cycle.
Richard, S.; Allison, L.; Clark, R.; Coleman, C.; Chen, G.
The US Geoscience information network has developed metadata profiles for interoperable catalog services based on ISO19139 and the OGC CSW 2.0.2. Currently data services are being deployed for the US Dept. of Energy-funded National Geothermal Data System. These services utilize OGC Web Map Services, Web Feature Services, and THREDDS-served NetCDF for gridded datasets. Services and underlying datasets (along with a wide variety of other information and non information resources are registered in the catalog system. Metadata for registration is produced by various workflows, including harvest from OGC capabilities documents, Drupal-based web applications, transformation from tabular compilations. Catalog search is implemented using the ESRI Geoportal open-source server. We are pursuing various client applications to demonstrated discovery and utilization of the data services. Currently operational applications allow catalog search and data acquisition from map services in an ESRI ArcMap extension, a catalog browse and search application built on openlayers and Django. We are developing use cases and requirements for other applications to utilize geothermal data services for resource exploration and evaluation.
Churi, Shobha; Abraham, Lovin; Ramesh, M; Narahari, M G
The aim of this study is to assess the nature and quality of services provided by poison information center established at a tertiary-care teaching hospital, Mysore. This was a prospective observational study. The poison information center was officially established in September 2010 and began its functioning thereafter. The center is equipped with required resources and facility (e.g., text books, Poisindex, Drugdex, toll free telephone service, internet and online services) to provide poison information services. The poison information services provided by the center were recorded in documentation forms. The documentation form consists of numerous sections to collect information on: (a) Type of population (children, adult, elderly or pregnant) (b) poisoning agents (c) route of exposure (d) type of poisoning (intentional, accidental or environmental) (e) demographic details of patient (age, gender and bodyweight) (f) enquirer details (background, place of call and mode of request) (g) category and purpose of query and (h) details of provided service (information provided, mode of provision, time taken to provide information and references consulted). The nature and quality of poison information services provided was assessed using a quality assessment checklist developed in accordance with DSE/World Health Organization guidelines. Chi-Square test (χ(2)). A total of 419 queries were received by the center. A majority (n = 333; 79.5%) of the queries were asked by the doctors to provide optimal care (n = 400; 95.5%). Most of the queries were received during ward rounds (n = 201; 48.0%), followed by direct access (n = 147; 35.1%). The poison information services were predominantly provided through verbal communication (n = 352; 84.0%). Upon receipt of queries, the required service was provided immediately (n = 103; 24.6%) or within 10-20 min (n = 296; 70.6%). The queries were mainly related to intentional poisoning (n = 258; 64.5%), followed by accidental poisoning
Vliet, van M.T.H.; Donnelly, Chantal; Strömbäck, Lena; Capell, René; Ludwig, Fulco
This study demonstrates a climate information service for pan-European water use sectors that are vulnerable to climate change induced hydrological changes, including risk and safety (disaster preparedness), agriculture, energy (hydropower and cooling water use for thermoelectric power) and
The paper recommends improvement in library budgetary allocation, more community sensitization on library services, urgent completion of the library complex at the main campus and commissioning of the e-library project. Key Words: Availability, utilization, information, resources, sources, academic, staff, university.
This necessitated the study, with a view to ascertaining if librarians in academic institutions, considering their location in rural areas, are involved in corporate social responsibility (CSR) by way of providing library and information services in communities? Using four federal tertiary institutions in Imo and Ebonyi states, South ...
Library and information sciences are experiencing a period of radical change. Today ... the customer base and fulfilling customer requirements and expectations? ... L'importance des services de garde d'enfants pour améliorer les possibilités ...
Risk management forms an integral part of the Library's planning and monitoring process and its internal control framework. It is therefore a vital element of good governance and management. This paper discusses the strategies for managing risks in the provision of information services in University Libraries. The concept ...
King, Donald W.; Brown, A. M.
This study was addressed to marketing considerations for the American Institute of Physics (AIP) information products and services. The general system and its operation in a marketing environment, including promotion, channels of distribution and pricing are covered. Particular emphasis is placed on the cost/demand/price relationship for four…
This dissertation consists of three essays that examine, in three specific contexts, issues related to pricing of information goods and services. As the ability to measure technology resource usage gets easier with increased connectivity, the question whether a technology resource should be priced by the amount of the resource used or by the…
Noel, Robert; Waugh, Timothy
This paper explores some of the similarities and differences between publicizing information services within the academic and corporate environments, comparing the marketing experiences of Abbot Laboratories (Illinois) and Indiana University. It shows some innovative online marketing tools, including an animated gif model of a large, integrated…
Weingand, Darlene E.
In the first edition of this book, the concepts of marketing and planning library and information services were presented as effective managerial strategies. Several paragraphs from the introduction to the first edition are reproduced, with author commentary, in this edition as an affirmation that the message is still true. In this second edition,…
Kampf, Rudolf; Ližbetinová, Lenka; Tišlerová, Kamila
This paper is focused on perceiving the logistic services as the competition advantage in frame of the ecommerce. Customers consider their purchases in its complexity and all the logistic services should be designed to meet with customers' preferences as much as possible. Our aim was to identify and evaluate of customers perceiving in frame of sales proposals offered by e-shops. Collected data of research were processed with the usage of cluster analysis. The aim of this paper is to present the results and conclusions from this research with focus on the elements of logistics services within e-commerce. These outputs can be used for knowledge base of information systems through which enterprises evaluate their decisions and selection of variants. For the enterprise, it is important to appropriate decisions about resource allocation and design of the structure of logistics services were set based on real customer preferences.
Fujii, T.; Nakatsuka, T.
Teratogenic to subteratogenic doses of x-ray, mitomycin C, MNNG, thio-TEPA, cyclophosphamide, and chlorambucil were administered to pregnant ICR mice together with caffeine at doses of 12.5, 25, or 50 mg/kg on day 11 of gestation. Fetuses were examined for gross malformations on day 18 of gestation. The teratogenicity of mitomycin C was significantly potentiated by caffeine at a dose as low as 12.5 mg/kg. The teratogenicity of chlorambucil was also significantly potentiated by caffeine at 50 mg/kg, but similar potentiation was not observed for x-ray, MNNG, thio-TEPA, and cyclophosphamide
Keeler, R F; Balls, L D
The plant Conium maculatum produced congenital defects in calves born to cows gavaged the fresh green plant during days 50-75 of gestation. Both arthrogryposis and spinal curvature were produced and were similar to the defects produced by the piperidine alkaloid coniine. The arthrogrypotic manifestations of the condition markedly increased in severity as the animals aged. Animals gavaged dry plant had either normal or equivocally deformed offspring. A number of chain length and ring saturation analogs of coniine were not teratogenic. No congenital defects arose in offspring from maternal inhalation of either the teratogenic alkaloid coniine, or from the teratogenic green plant.
Full Text Available Article assesses the impact of adverse factors on intrauterine development of the child, first of all, drugs. The author stresses that the importance of drug safety (D is due to the large number of unintended pregnancies worldwide. A list of the D, providing proven teratogenic effects on a child organism is presenting. It is shown that the D teratogenic effect in humans can not be assessed on the basis of experimental data obtained in animals due to the difference between metabolic and detoxification processes in a different mammals and individuals. Key words: drugs, safety, teratogenic effects, fetal development, the unborn child. (Pediatric pharmacology. — 2011; 8 (6: 57–60.
The Information Services Directory is intended to facilitate dissemination of information. The Directory is produced by the Information Services Division of OCRWM's Office of External Relations and Policy and will be updated periodically. This is the second such update since its issuance in August 1986. It is a reference document that lists the sources of program information available to States, Indian Tribes and the public. Chapter I of this Directory describes current program information sources, including the OCRWM Bulletin, the Electronic Bulletin Board (INFOLINK) and other periodic publications produced by OCRWM and DOE's Office of Scientific and Technical Information (OSTI). Chapter II is an index of DOE, State and Federal Agency contacts. Chapter III provides a directory of DOE technical information and includes descriptions of computerized data bases and other resources. Chapter IV enumerates Congressional Committees and Subcommittees that have jurisdiction over various components of the Civilian Radioactive Waste Management Program, and Chapter V lists DOE Reading Rooms and Information Offices, NRC Local Public Document Rooms, and public libraries in the State of Nevada that are on one or more of OCRWM's mailing lists. Chapter VI is an index of systems and Chapter VII offers listings of selected publications
Full Text Available We present in this paper the design, development and pilot process of the Lwazi community communication service (LCCS), a multilingual automated telephone-based information service. The service acts as a communication and dissemination tool...
Grønbæk, Kaj; Rohde, Anne; Sundararajah, Balasuthas
Much focus in digital libraries research has been devoted to new online services rather than services for the visitors in the physical library. This paper describes InfoGallery, which is a web-based infrastructure for enriching the physical library space with informative art "exhibitions......" of digital library material and other relevant information, such as RSS news streams, event announcements etc. InfoGallery presents information in an aesthetically attractive manner on a variety of surfaces in the library, including cylindrical displays and floors. The infrastructure consists of a server...... structure, an editor application and a variety of display clients. The paper discusses the design of the infrastructure and its utilization of RSS, podcasts and manually edited news. Applications in the library domain are described and the experiences are discussed....
Full Text Available With the further development of information and communication technology and a growing use of smart phones, the significance of Geographic Information System - GIS will indisputably continue to grow. This is supported by the fact that in the last decade geotechnology has been identified as one of the fastest growing technologies, along with biotechnology and nanotechnology. Even though GIS is increasingly being utilized in the Republic of Serbia, it appears that its use with some providers of public services is mainly deduced to showing spatial data with quite limited possibilities for a further analysis - which represents the essence of the use of GIS. The scope of this paper is to stress the outstanding analytical potential that GIS has in the domain of offering and improving various public services in the Republic of Serbia. The paper uses the examples of good practice in the sphere of the health system, public safety, rescue services and local government. The covered examples show that the use of the analytical component of GIS in everyday activities of the mentioned public services can make their work not only more transparent to the public, but considerably more efficient as well. This way, the analytical component of GIS enables decision-makers to improve the management of frequently limited available resources, while proving a higher level of the service quality to citizens as the final users.
Kolos, S; Boutsioukis, G; Hauser, R
The ATLAS experiment is operated by a highly distributed computing system which is constantly producing a lot of status information which is used to monitor the experiment operational conditions as well as to assess the quality of the physics data being taken. For example the ATLAS High Level Trigger(HLT) algorithms are executed on the online computing farm consisting from about 1500 nodes. Each HLT algorithm is producing few thousands histograms, which have to be integrated over the whole farm and carefully analyzed in order to properly tune the event rejection. In order to handle such non-physics data the Information Service (IS) facility has been developed in the scope of the ATLAS Trigger and Data Acquisition (TDAQ) project. The IS provides a high-performance scalable solution for information exchange in distributed environment. In the course of an ATLAS data taking session the IS handles about a hundred gigabytes of information which is being constantly updated with the update interval varying from a second to a few tens of seconds. IS provides access to any information item on request as well as distributing notification to all the information subscribers. In the latter case IS subscribers receive information within a few milliseconds after it was updated. IS can handle arbitrary types of information, including histograms produced by the HLT applications, and provides C++, Java and Python API. The Information Service is a unique source of information for the majority of the online monitoring analysis and GUI applications used to control and monitor the ATLAS experiment. Information Service provides streaming functionality allowing efficient replication of all or part of the managed information. This functionality is used to duplicate the subset of the ATLAS monitoring data to the CERN public network with a latency of a few milliseconds, allowing efficient real-time monitoring of the data taking from outside the protected ATLAS network. Each information
Langarizadeh, Mostafa; Moghbeli, Fatemeh; Aliabadi, Ali
Advanced technology has increased the use of telemedicine and Information Technology (IT) in treating or rehabilitating diseases. An increased use of technology increases the importance of the ethical issues involved. The need for keeping patients' information confidential and secure, controlling a number of therapists' inefficiency as well as raising the quality of healthcare services necessitates adequate heed to ethical issues in telemedicine provision. The goal of this review is gathering all articles that are published through 5 years until now (2012-2017) for detecting ethical issues for providing telemedicine services and Information technology. The reason of this time is improvement of telemedicine and technology through these years. This article is important for clinical practice and also to world, because of knowing ethical issues in telemedicine and technology are always important factors for physician and health providers. the required data in this research were derived from published electronic sources and credible academic articles published in such databases as PubMed, Scopus and Science Direct. The following key words were searched for in separation and combination: tele-health, telemedicine, ethical issues in telemedicine. A total of 503 articles were found. After excluding the duplicates (n= 93), the titles and abstracts of 410 articles were skimmed according to the inclusion criteria. Finally, 64 articles remained. They were reviewed in full text and 36 articles were excluded. At the end, 28 articles were chosen which met our eligibility criteria and were included in this study. Ethics has been of a great significance in IT and telemedicine especially the Internet since there are more chances provided for accessing information. It is, however, accompanied by a threat to patients' personal information. Therefore, suggestions are made to investigate ethics in technology, to offer standards and guidelines to therapists. Due to the advancement in
...] Notice of Request for Approval of an Information Collection; National Veterinary Services Laboratories... Service's intention to request approval of an information collection associated with National Veterinary...' Information Collection Coordinator, at (301) 851-2908. SUPPLEMENTARY INFORMATION: Title: National Veterinary...
Marshall, Joanne Gard; Morgan, Jennifer Craft; Thompson, Cheryl A; Wells, Amber L
The purpose of this paper is to explore library and information service impact on patient care quality. A large-scale critical incident survey of physicians and residents at 56 library sites serving 118 hospitals in the USA and Canada. Respondents were asked to base their answers on a recent incident in which they had used library resources to search for information related to a specific clinical case. Of 4,520 respondents, 75 percent said that they definitely or probably handled patient care differently using information obtained through the library. In a multivariate analysis, three summary clinical outcome measures were used as value and impact indicators: first, time saved; second, patient care changes; and third, adverse events avoided. The outcomes were examined in relation to four information access methods: first, asking librarian for assistance; second, performing search in a physical library; third, searching library's web site; or fourth, searching library resources on an institutional intranet. All library access methods had consistently positive relationships with the clinical outcomes, providing evidence that library services have a positive impact on patient care quality. Electronic collections and services provided by the library and the librarian contribute to patient care quality.
Vlietland, J.; Vliet, J.C.
Information technology (IT)-enabled financial services are typically delivered by a network of interdependent IT service providers. Such networks need information to resolve IT incidents in their delivered IT services. The objective of this research is to identify the set of information that needs
to compensate the failure and the organism will die. Teratogenic agents can be classified according to the developmental mechanism that they affect. Some of these agents act modifying the genomic information or its expression meanwhile others can alter interactions among cells, or between cells and microenvironment. According to the genetic background, the same teratogenic agent might or not establish a malformation. Besides, another external factors modulate the effect of a teratogen or the genetic background, for example: folic acid can prevent abnormalities in the neural tube closure. In conclusion, it is possible to affirm that the development of normal and abnormal phenotypes depend on complex interactions that are far from be understood now and taking part interactions between genes and environment are still obscure. Besides, there are not animal models that could copy either human development or the developmental mechanisms that produce malformations. The solutions to these subjects will arise from a detailed study of prenatal and postnatal developmental biology and genetics, and taking into account the influence of environment on living organisms. (author)
Timofeyeva, M. M.; Higgins, W.; Strager, C.; Horsfall, F. M.
NOAA is an active participant of the Global Framework for Climate Services (GFCS) contributing data, information, analytical capabilities, forecasts, and decision support services to the Climate Services Partnership (CSP). These contributions emerge from NOAA's own climate services, which have evolved to respond to the urgent and growing need for reliable, trusted, transparent, and timely climate information across all sectors of the U.S. economy. Climate services not only enhance development opportunities in many regions, but also reduce vulnerability to climate change around the world. The NOAA contribution lies within the NOAA Climate Goal mission, which is focusing its efforts on four key climate priority areas: water, extremes, coastal inundation, and marine ecosystems. In order to make progress in these areas, NOAA is exploiting its fundamental capabilities, including foundational research to advance understanding of the Earth system, observations to preserve and build the climate data record and monitor changes in climate conditions, climate models to predict and project future climate across space and time scales, and the development and delivery of decision support services focused on risk management. NOAA's National Weather Services (NWS) is moving toward provision of Decision Support Services (DSS) as a part of the Roadmap on the way to achieving a Weather Ready National (WRN) strategy. Both short-term and long-term weather, water, and climate information are critical for DSS and emergency services and have been integrated into NWS in the form of pilot projects run by National and Regional Operations Centers (NOC and ROCs respectively) as well as several local offices. Local offices with pilot projects have been focusing their efforts on provision of timely and actionable guidance for specific tasks such as DSS in support of Coastal Environments and Integrated Environmental Studies. Climate information in DSS extends the concept of climate services to
Brustolin, Silvia; Souza, Carolina; Puga, Ana Cristina; Refosco, Lilia; Pires, Ricardo; Peres, Rossana; Giugliani, Roberto
The Information Service on Inborn Errors of Metabolism (SIEM), a pioneer toll-free service in both Brazil and South America, is based in Porto Alegre, Southern Brazil. SIEM has been operating since October 2001 providing support to health care professionals involved in the diagnosis and management of suspected metabolic diseases. We analyzed the demographic and clinical characteristics of the 376 consults received and followed in the first two and half years of SIEM. Our results show that the suspicion of a metabolic disease was most often associated with neurological symptoms. Among the consults, 24.4% were eventually confirmed as inborn errors of metabolism (IEM), with organic acidurias and amino acid disorders being the two most frequent diagnostic groups. Our conclusion shows this kind of service to provide helpful support to the diagnosis and acute management of IEM, especially to health professionals working in developing countries who are often far from reference centers.
Haruna, Hussein; Mtoroki, Majaliwa; Gerendasy, Dan D; Detlefsen, Ellen G
The intention of the Government of Tanzania is to establish more health information resource canters in all health facilities. With this regard, health information science personnel are needed to provide adequate and accurate health information services. However, availability of these personnel remains to be a challenge because of their non-existence. To identify the current status and local impact of health sciences libraries and user perception of these libraries, as a prerequisite to the development of a competence-based curriculum for health information science training in Tanzania. A needs assessment was carried out using a convenience sample of local respondents, including librarians, trainers, academicians, students, health care providers, and patients and families, drawn from national, referral, regional, district hospitals, health training institutions, and universities from both government and nongovernment entities in Tanzania. A focus group approach was used to gather data from respondents. Results from this assessment revealed that health science libraries in Tanzania are faced with the challenges of insufficient infrastructure, old technology, limited facilities and furniture, inadequate and incompetent library staff, lack of health sciences librarians, outdated and insufficient resources, and low knowledge and use of information technologies by library clients. Most respondents would prefer to have both physical and electronic libraries, as well as librarians with specialized health information science skills, to cope with changing nature of the medical field. The findings obtained from this assessment are strong enough to guide the development of a curriculum and training strategy and an operational plan and training packages for health information professionals. The development of a training curriculum for health information science professionals will mean better health information service delivery for Tanzania. Copyright © 2016 Icahn School of
Radulovic, Aleksandra; Sladic, Dubravka; Govedarica, Miro; Popovic, Dragana; Radovic, Jovana
Since the data of cadastral records are of great importance for the economic development of the country, they must be well structured and organized. Records of real estate on the territory of Serbia met many problems in previous years. To prevent problems and to achieve efficient access, sharing and exchange of cadastral data on the principles of interoperability, domain model for real estate is created according to current standards in the field of spatial data. The resulting profile of the domain model for the Serbian real estate cadastre is based on the current legislation and on Land Administration Domain Model (LADM) which is specified in the ISO19152 standard. Above such organized data, and for their effective exchange, it is necessary to develop a model of services that must be provided by the institutions interested in the exchange of cadastral data. This is achieved by introducing a service-oriented architecture in the information system of real estate cadastre and with that ensures efficiency of the system. It is necessary to develop user services for download, review and use of the real estate data through the web. These services should be provided to all users who need access to cadastral data (natural and legal persons as well as state institutions) through e-government. It is also necessary to provide search, view and download of cadastral spatial data by specifying geospatial services. Considering that real estate contains geometric data for parcels and buildings it is necessary to establish set of geospatial services that would provide information and maps for the analysis of spatial data, and for forming a raster data. Besides the theme Cadastral parcels, INSPIRE directive specifies several themes that involve data on buildings and land use, for which data can be provided from real estate cadastre. In this paper, model of geospatial services in Serbia is defined. A case study of using these services to estimate which household is at risk of
Gao, Sheng; Mioc, Darka; Anton, François
Background Disease data sharing is important for the collaborative preparation, response, and recovery stages of disease control. Disease phenomena are strongly associated with spatial and temporal factors. Web-based Geographical Information Systems provide a real-time and dynamic way to represent...... and responding to disease outbreaks. To overcome these challenges in disease data mapping and sharing, the senior authors have designed an interoperable service oriented architecture based on Open Geospatial Consortium specifications to share the spatio-temporal disease information. Results A case study...... of infectious disease mapping across New Brunswick (Canada) and Maine (USA) was carried out to evaluate the proposed architecture, which uses standard Web Map Service, Styled Layer Descriptor and Web Map Context specifications. The case study shows the effectiveness of an infectious disease surveillance system...
Gross-Fengels, W.; Weber, M.
By means of complete service control and standardized accounting processes, radiological information systems clearly contribute to improved results. They provide the prerequisites for the establishment of expanded networks and allow comprisons with comparable institutions. The quality of patient care can be improved since, for example, the production time from referral to finished result becomes shorter. Direct access to patient and findings data from several positions is possible. Preliminary results can be viewed immediately. The patient's history is accessible to authorized users at all times. The exact reproducibility and assignment of services leads to more clarity. By means of the information available form RIS, rapid adaptive processes can be undertaken. The system assists the to fulfill the requirements of health regulations. The above-mentioned relationships demonstrate that the EDP systems are well accepted by physicians, medical assistants, and administrators and represent an indispensable aid for solving problems. (orig.) [de
... Proposed Information Collection: Indian Health Service Customer Satisfaction Survey AGENCY: Indian Health...: 0917-NEW, ``Indian Health Service Customer Satisfaction Survey.'' Type of Information Collection... facilities programs will make improvements that will result in improved quality of services. Voluntary...
... DEPARTMENT OF THE TREASURY Fiscal Service Financial Management Service; Proposed Collection of Information: Request for Payment of Federal Benefit by Check, EFT Waiver Form AGENCY: Financial Management... to Financial Management Service, 3700 East West Highway, Records and Information Management Branch...
...] Notice of Request for Approval of an Information Collection; National Veterinary Services Laboratories... collection associated with the National Veterinary Services Laboratories animal health diagnostic system...: For information on request forms associated with the National Veterinary Services Laboratories animal...
Full Text Available European parking information center (EPIC – it will provide unified and detailed information about European parking areas. The EPIC system will receive the data from local information centres. For Slovak republic there will be one provider for traffic data – a National traffic information center (NDIC. The EPIC system is available at http://truckinform.eu. Intelligent parking system (IPS will be linked with NDIC. The aim of the IPS system is to provide information as follows: number of free parking places, services to be used in parking area and so one.
Augustine-Rauch, K A
Unexpected teratogenicity is ranked as one of the most prevalent causes for toxicity-related attrition of drug candidates. Without proactive assessment, the liability tends to be identified relatively late in drug development, following significant investment in compound and engagement in pre clinical and clinical studies. When unexpected teratogenicity occurs in pre-clinical development, three principle questions arise: Can clinical trials that include women of child bearing populations be initiated? Will all compounds in this pharmacological class produce the same liability? Could this effect be related to the chemical structure resulting in undesirable off-target adverse effects? The first question is typically addressed at the time of the unexpected finding and involves considering the nature of the teratogenicity, whether or not maternal toxicity could have had a role in onset, human exposure margins and therapeutic indication. The latter two questions can be addressed proactively, earlier in the discovery process as drug target profiling and lead compound optimization is taking place. Such proactive approaches include thorough assessment of the literature for identification of potential liabilities and follow-up work that can be conducted on the level of target expression and functional characterization using molecular biology and developmental model systems. Developmental model systems can also be applied in the form of in vitro teratogenicity screens, and show potential for effective hazard identification or issue resolution on the level of characterizing teratogenic mechanism. This review discusses approaches that can be applied for proactive assessment of compounds for teratogenic liability.
...] Notice of Request for Extension of Approval of an Information Collection; Veterinary Services Customer... an extension of approval of an information collection to evaluate service delivery by Veterinary... coming. FOR FURTHER INFORMATION CONTACT: For information on the Veterinary Services customer service...
de Vries, Loes C; de Swart, Irene W; van Puijenbroek, Eugène P
Many women use medication during pregnancy. Both the healthcare professional and the pregnant woman often have many questions about the possible adverse effects of the medication that are not always answered in the product information. The Teratology Information Service (TIS), a part of the Netherlands Pharmacovigilance Centre Lareb, is a centre of expertise in the field of the safety of medication use and other external influences during spermatogenesis, pregnancy and lactation. The TIS collects, interprets, and disseminates information that can contribute to patient care. Healthcare professionals can contact the TIS for information and individual risk assessments. In this article we discuss the background and positioning of the TIS, the characteristics of telephone consultations, the collection of data and the considerations that are important for the use of medication during pregnancy and lactation.
Mazet-Roux, G.; Godey, S.; Bossu, R.
The EMSC (http://www.emsc-csem.org) operates Real Time Earthquake Information services for the public and the scientific community which aim at providing rapid and reliable information on the seismic-ity of the Euro-Mediterranean region and on significant earthquakes worldwide. These services are based on parametric data rapidly provided by 66 seismological networks which are automatically merged and processed at EMSC. A web page which is updated every minute displays a list and a map of the latest earthquakes as well as additional information like location maps, moment tensors solutions or past regional seismicity. Since 2004, the performances and the popularity of these services have dramatically increased. The number of messages received from the contributors and the number of published events have been multiplied by 2 since 2004 and by 1.6 since 2005 respectively. The web traffic and the numbers of users of the Earthquake Notification Service (ENS) have been multiplied by 15 and 7 respectively. In terms of performances of the ENS, the median dissemination time for Euro-Med events is minutes in 2008. In order to further improve its performances and especially the speed and robustness of the reception of real time data, EMSC has recently implemented a software named QWIDS (Quake Watch Information Distribution System) which provides a quick and robust data exchange system through permanent TCP connections. At the difference with emails that can sometimes be delayed or lost, QWIDS is an actual real time communication system that ensures the data delivery. In terms of hardware, EMSC imple-mented a high availability, dynamic load balancing, redundant and scalable web servers infrastructure, composed of two SUN T2000 and one F5 BIG-IP switch. This will allow coping with constantly increas-ing web traffic and the occurrence of huge peaks of traffic after widely felt earthquakes.
... DEPARTMENT OF THE TREASURY Fiscal Service Financial Management Service; Proposed Collection of Information: Electronic Funds Transfer (EFT) Market Research Study AGENCY: Financial Management Service, Fiscal Service, Treasury. ACTION: Notice and Request for comments. SUMMARY: The Financial Management...
... DEPARTMENT OF THE TREASURY Fiscal Service Financial Management Service; Proposed Collection of Information: Final Rule--Management of Federal Agency Disbursements. AGENCY: Financial Management Service, Fiscal Service, Treasury. ACTION: Notice and Request for comments. SUMMARY: The Financial Management...
... DEPARTMENT OF THE TREASURY Fiscal Service Financial Management Service; Proposed Collection of Information: Annual Financial Statement of Surety Companies--Schedule F AGENCY: Financial Management Service, Fiscal Service, Treasury. ACTION: Notice and Request for comments. SUMMARY: The Financial Management...
... DEPARTMENT OF THE TREASURY Fiscal Service Financial Management Service; Proposed Collection of Information: Authorization Agreement for Preauthorized Payment (SF 5510) AGENCY: Financial Management Service, Fiscal Service, Treasury. ACTION: Notice and request for comments. SUMMARY: The Financial Management...
Erwin, James; Eberline, Carl; Colquitt, Wanda
Today we are in the midst of information and 'total quality' revolutions. At the NASA STI Program's Center for AeroSpace Information (CASI), we are focused on using continuous improvements techniques to enrich today's services and products and to ensure that tomorrow's technology supports the TQM-based improvement of future STI program products and services. The Continuous Improvements Program at CASI is the foundation for Total Quality Management in products and services. The focus is customer-driven; its goal, to identify processes and procedures that can be improved and new technologies that can be integrated with the processes to gain efficiencies, provide effectiveness, and promote customer satisfaction. This Program seeks to establish quality through an iterative defect prevention approach that is based on the incorporation of standards and measurements into the processing cycle. Four projects are described that utilize cross-functional, problem-solving teams for identifying requirements and defining tasks and task standards, management participation, attention to critical processes, and measurable long-term goals. The implementation of these projects provides the customer with measurably improved access to information that is provided through several channels: the NASA STI Database, document requests for microfiche and hardcopy, and the Centralized Help Desk.
Bros, Juan; Marcelles, Ignacio
The Spanish nuclear regulatory authority, the Consejo de Seguridad Nuclear (CSN), requires the use of codes and standards in force in the country of origin of the plant technology. For this reason, the in-service inspection and testing programs applied at Spanish nuclear power plants basically adhere to the requirements of the ASME XI and ASME OM Codes. It is not surprising that when the earliest developments aimed at drawing up risk informed inservice inspection and testing programs were initiated within the framework of ASME, the Spanish industry should follows such developments very closely. In fact, persons within the Spanish nuclear industry joined different ASME committees involved in the development and approval of the various code cases encompassing these developments. Developments specific to the Spanish nuclear power plants were initiated at a time when the aforementioned reference documentation was in a very advanced stage of development/approval. Two clearly differentiated lines of work got under way: On the one hand, and as regards risk informed in-service testing programs, the American standards were used as the sole reference. In the case of risk informed in-service inspection programs, the Spanish nuclear power plant-owning utilities and the Consejo de Seguridad Nuclear decided to draw up a Spanish guideline that, although using the ASME developments as a reference, would have its own specific characteristics. In relation to the above, and referring to the chronology of the events, the activities performed to date in Spain are described
В. В. Степко
Full Text Available The article highlights information resources of the scientific library of the Kiev National University of Culture and Arts and characterizes its use in the system of providing librarian and informational services for users. It is proved that the important information resource of the library is website, which provides additional opportunities for users, forming a positive image of the library in the virtual space. The site contains information on various directions of the library’s activities, librarian services, projects and media products. One of the main tasks of the library is formation and presentation on the website of the electronic catalog as a multifunctional bibliographic resource, which is the basis for informational services and the basic information product of the library. The creation of an electronic library continues as the essential element of providing qualitative and effective services to users. The article discusses the functioning of the “Virtual Help” service as an effective form of working with remote users. The authors also consider such an actual direction of the library’s activity as the presentation of the scientific and creative heritage of the university with help of “12 + books of the year” project. The aim of the project is to inform about new editions of university’s teachers published this year and presented in the library fund. The implementation of the patriotic innovation and educational project “Treasures of the Nation”, whose purpose is to study and popularize the elements of the intangible cultural heritage ofUkraine, is analyzed. The booktrails and flash presentations are considered as a means of presenting books prepared by the library staff. The preparation of longreed, a new format for submitting information on the Internet, is also considered. Thanks to the use of Tilda Publishing and ThingLink services, innovative products were created: a complex multimedia story that combined photos
Kurtz, M. J.; Eichhorn, G.; Accomazzi, A.; Grant, C. S.; Murray, S. S.
The NASA Astrophysics Data System Astrophysics Science Information and Abstract Service, the extension of the ADS Abstract Service continues rapidly to expand in both use and capabilities. Each month the service is used by about 4,000 different people, and returns about 1,000,000 pieces of bibliographic information. Among the recent additions to the system are: 1. Whole Text Access. In addition to the ApJ Letters we now have whole text for the ApJ on-line, soon we will have AJ and Rev. Mexicana. Discussions with other publishers are in progress. 2. Space Instrumentation Database. We now provide a second abstract service, covering papers related to space instruments. This is larger than the astronomy and astrophysics database in terms of total abstracts. 3. Reference Books and Historical Journals. We have begun putting the SAO Annals and the HCO Annals on-line. We have put the Handbook of Space Astronomy and Astrophysics by M.V. Zombeck (Cambridge U.P.) on-line. 4. Author Abstracts. We can now include original abstracts in addition to those we get from the NASA STI Abstracts Database. We have included abstracts for A&A in collaboration with the CDS in Strasbourg, and are collaborating with the AAS and the ASP on others. We invite publishers and editors of journals and conference proceedings to include their original abstracts in our service; send inquiries via e-mail to email@example.com. 5. Author Notes. We now accept notes and comments from authors of articles in our database. These are arbitrary html files and may contain pointers to other WWW documents, they are listed along with the abstracts, whole text, and data available in the index listing for every reference. The ASIAS is available at: http://adswww.harvard.edu/
Xu, Xianbin; Wu, Qunyong; Wang, Qinmin
With Web services technology the functions of WebGIS can be presented as a kind of geospatial information service, and helped to overcome the limitation of the information-isolated situation in geospatial information sharing field. Thus Geospatial Information Web service composition, which conglomerates outsourced services working in tandem to offer value-added service, plays the key role in fully taking advantage of geospatial information services. This paper proposes an automatic geospatial information web service composition algorithm that employed the ontology dictionary WordNet to analyze semantic distances among the interfaces. Through making matching between input/output parameters and the semantic meaning of pairs of service interfaces, a geospatial information web service chain can be created from a number of candidate services. A practice of the algorithm is also proposed and the result of it shows the feasibility of this algorithm and the great promise in the emerging demand for geospatial information web service composition.
Ge, Ningning; Zang, Zhiyuan; Gao, Lingwang; Shi, Qiang; Li, Jie; Xing, Chunlin; Shen, Zuorui
Internet cannot provide perfect information services for farmers in rural regions in China, because farmers in rural regions can hardly access the internet by now. But the wide coverage of mobile signal, telephone line, and television network, etc. gave us a chance to solve the problem. The integrated pest management platform of Northern fruit trees were developed based on the integrated technology, which can integrate the internet, mobile and fixed-line telephone network, and television network, to provide integrated pest management(IPM) information services for farmers in rural regions in E-mail, telephone-voice, short message, voice mail, videoconference or other format, to users' telephone, cell phone, personal computer, personal digital assistant(PDA), television, etc. alternatively. The architecture and the functions of the system were introduced in the paper. The system can manage the field monitoring data of agricultural pests, deal with enquiries to provide the necessary information to farmers accessing the interactive voice response(IVR) in the system with the experts on-line or off-line, and issue the early warnings about the fruit tree pests when it is necessary according to analysis on the monitoring data about the pests of fruit trees in variety of ways including SMS, fax, voice and intersystem e-mail.The system provides a platform and a new pattern for agricultural technology extension with a high coverage rate of agricultural technology in rural regions, and it can solve the problem of agriculture information service 'last kilometer' in China. The effectiveness of the system was certified.
... Acquisition Regulation; Implementation of Information Technology Security Provision AGENCY: Office of... information technology (IT) supplies, services and systems with security requirements. DATES: Effective Date... effective date that include information technology (IT) supplies, services and systems with security...
... Acquisition Regulation; Implementation of Information Technology Security Provision AGENCY: Office of... orders that include information technology (IT) supplies, services and systems. DATES: Effective Date... 6, 2012 that include information technology (IT) supplies, services and systems with security...
.... Information Technology Help Desk Services Including On-Site Leased Workers From Modis, West Norriton, PA..., applicable to workers of Quest Diagnostics, Inc., Information Technology Help Desk Services, West Norriton... Quest Diagnostics, Inc., Information Technology Help Desk [[Page 2145
Heijden, van der H.
In this paper we develop a conceptual framework around the attitudes and intentions towards using online information service, and we theorise about thedifferences in relationships between regular information systems and online information services, Specifically we hypothesize (1) that affect
Bray, S. E.
A vision was presented in a previous paper of how a common set of services within a framework could be used to provide all the information processing needs of Warfighters. Central to that vision was the concept of a "Virtual Knowledge Base". The paper presents an implementation of these ideas in the intelligence domain. Several innovative technologies were employed in the solution, which are presented and their benefits explained. The project was successful, validating many of the design principles for such a system which had been proposed in earlier work. Many of these principles are discussed in detail, explaining lessons learned. The results showed that it is possible to make vast improvements in the ability to exploit available data, making it discoverable and queryable wherever it is from anywhere within a participating network; and to exploit machine reasoning to make faster and better inferences from available data, enabling human analysts to spend more of their time doing more difficult analytical tasks rather than searching for relevant data. It was also demonstrated that a small number of generic Information Processing services can be combined and configured in a variety of ways (without changing any software code) to create "fact-processing" workflows, in this case to create different intelligence analysis capabilities. It is yet to be demonstrated that the same generic services can be reused to create analytical/situational awareness capabilities for logistics, operations, planning or other military functions but this is considered likely.
Timofeyeva-Livezey, M. M.; Horsfall, F. M. C.; Pulwarty, R. S.; Klein-Tank, A.; Kolli, R. K.; Hechler, P.; Dilley, M.; Ceron, J. P.; Goodess, C.
The WMO Commission on Climatology (CCl) supports the implementation of the Global Framework for Climate Services (GFCS) with a particular focus on the Climate Services Information System (CSIS), which is the core operational component of GFCS at the global, regional, and national level. CSIS is designed for producing, packaging and operationally delivering authoritative climate information data and products through appropriate operational systems, practices, data exchange, technical standards, authentication, communication, and product delivery. Its functions include climate analysis and monitoring, assessment and attribution, prediction (monthly, seasonal, decadal), and projection (centennial scale) as well as tailoring the associated products tUEAo suit user requirements. A central, enabling piece of implementation of CSIS is a Climate Services Toolkit (CST). In its development phase, CST exists as a prototype (www.wmo.int/cst) as a compilation of tools for generating tailored data and products for decision-making, with a special focus on national requirements in developing countries. WMO provides a server to house the CST prototype as well as support operations and maintenance. WMO members provide technical expertise and other in-kind support, including leadership of the CSIS development team. Several recent WMO events have helped with the deployment of CST within the eight countries that have been recognized by GFCS as illustrative for developing their climate services at national levels. Currently these countries are developing climate services projects focusing service development and delivery for selected economic sectors, such as for health, agriculture, energy, water resources, and hydrometeorological disaster risk reduction. These countries are working together with their respective WMO Regional Climate Centers (RCCs), which provide technical assistance with implementation of climate services projects at the country level and facilitate development of
Nobakht, M; Zirak, A; Mehdizadeh, M; Tabatabaeei, P
Retinoic acids (RA) are natural chemicals that exert a hormone-like activity and a variety of biological effects on early development of mouse. In this study, the probable teratogenic effects of RA on CNS have been investigated in pregnant mice (n = 20) divided into four groups: (1) untreated controls, (2) controls which received a single dose of DMSO, (3) a group that received 40 mg/kg, and (4) a group that received 60 mg/kg of all-trans RA in DMSO, respectively on the eighth day of gestation. Embryos whose dams had received 40 and 60 mg/kg doses of RA, showed malformations and decreased size. At 40 mg/kg dosage level, 50% of the embryos had closed neural tubes while at 60 mg/kg dosage level the neural tube failed to close. The neuroblast mantle layers were disorganized in the 40 mg/kg and even more in the 60 mg/kg exposed group compared to the controls. In mitosis, the density of chromatin was increased in the 60 mg/kg dose group. Compared to controls the 40 and 60 mg/kg dose groups of RA treated dams decreases in the luminal longitudinal and internal measures were observed. Also the thickness of ventricular, mantle and marginal layers was smaller. Wide intercellular spaces due to the degenerated cells at high doses of RA as well as an accumulation of intercellular fluid were observed. Therefore, the wedge shape of neuroepithelium was abolished, preventing the elevation of the neural wall.
Sharma, R.P.; Willhite, C.C.; Berry, D.L.; Allen, P.V.
Oral retinoid treatment can be teratogenic and topical applications are used to treat acne and smooth wrinkles. A single topical trace (2.5 μg; 191 μCi/kg) or high (1.3 mg; 195 μCi/kg) dose of all-trans-[10, 11- 3 H 2 ] retinoic acid (RA) dissolved in acetone was applied to 4 cm 2 shaved dorsal hamster skin. Peak plasma radioactivity (C max ) occurred at 12 and 36 hr and mean t1/2 values for parent PA absorption were 48 min and 2.8 hr, for trace and high dose, respectively. The dermal RA C max values were only 2% of that after an equivalent oral dose, but plasma AUC after dermal treatment was 63% of the oral value. The mean t1/2 for rapid elimination was shorter for the high (57 min) than for the trace (6.9 hr) dose, but t1/2 values for slow elimination were comparable (t1/2 high = 51.2 hr; t1/2 trace = 36.8 hr). Single topical application of 10-30 mg/kg RA or 5 mg/kg etretinate (Ro 10-9359) to pregnant hamsters (day 8) caused local hyperkeratosis, but failed to induce terata. Similar application of 10-1000 μg/kg arotinoid Ro 13-6298 caused dose-dependent terata, being twice as embryolethal by parenteral as enteric dosing. Skin toxicity and attenuated maternal blood levels limit the amount of retinoids that can reach the embryo
River Information Services (RIS) is the complex system of solutions and services for inland shipping. It has been the scope of works carried out in most of European countries for last several years. There were also a few major pan-European projects like INDRIS or COMPRIS launched for these purposes. The main idea of RIS is to harmonize the activities of various companies, authorities and other users of inland waterways in Europe. In the last time growing activity in this area in Poland can be also noticed. The leading example can be the works carried out in Chair of Geoinformatics in Maritime University of Szczecin regarding RIS for the needs of Odra River. The Directive 2005/44/EC of European Parliament and Europe Council, followed by European Commission regulations, give precise guidelines on implementing RIS in Europe, stating the services that should be provided. Among them Traffic Information and Traffic Management services can be found. As per guidelines they should be based on tracking and tracing of ships in the inland waters. The results of tracking and tracing are Tactical Traffic Image and Strategic Traffic Image. The guidelines stated that, tracking and tracing system in RIS shall consist of various type sensors. The most important of them is thought to be Automatic Information System (AIS), and particularly its river version - Inland AIS. It is based on determining the position of ships by satellite positioning systems (mainly DGPS) and transmitting it to other users on radio VHF frequences. This guarantees usually high accuracy of data related to movement of ships (assuming proper functioning of system and ship's sensors), and gives the possibility of transmitting additional information about ship, like dimensions, port of destination, cargo, etc. However the other sensors that can be used for tracking shall not be forgotten. The most important of them are radar (traditionally used for tracking purposes in Vessel Traffic Systems) and video camera
Ting, K.; Ko, T.-H.; Li, Y.-C.; Wu, W.-F.; Lu, Y.-L.; Chien, F.-T.
The US NRC and nuclear industry encouraged the applications of risk-informed In-Service Inspection (RI-ISI) which can be an alternative program to the ASME Section XI In-service Inspection requirements. The Implementation of RI-ISI can improve the substantial cost as well as does reductions. From the aspect of defense in depth for nuclear safety, the achievements of these procedures can identify the inspection rank to promote the integrity of the current inspection program. Thus, this study utilizes this techniques to implement risk assessment on safety class 1 recirculation piping welds where sensitized to IGSCC of Taibei BWR-6 nuclear power plant. In the evaluation process, WinPraise code is used to calculate the failure probabilities of all welds. The result of risk evaluations can be referred to the further regulatory and plant operation. (authors)
The radiation protection group reminds you that the import/export of all radioactive material must be declared in advance. In the case of exports, an EDH shipping request form must be completed, ticking the box “radioactive material”. In the case of imports, an electronic form must be completed before the material arrives on the CERN site. Any requests which do not comply with the above procedure will be refused. The import of any radioactive material that has not been declared in advance will be systematically refused. For further information, please consult the web site: http://cern.ch/service-rp-shipping Yann Donjoux / Radioactive Shipping Service Tél: +41 22 767.31.71 Fax: +41 22 766.92.00
Lei, B.; Liu, K.; Gan, Y.; Zhong, M.
Accompanying infrastructure improvements and networking technology innovation, the development of digital home service industry has gotten more and more attention. However, the digital home service levels have not sufficiently met rising demand from users. Therefore, it is urgent to propose and develop new service modes for the digital home. Geographic information services can provide various spatial information services such as map search, spatial information query. It has become an inevitable trend to implement geographic information services in the digital home. This paper proposes three new geographic information services modes for the digital home after sufficient requirement analysis: pushed information service mode, interactive information service mode, personalized information service mode. The key technologies to implement geographic information services on digital televisions are studied, involving digital television middleware technology, network transmission technology and visualization technology. According to the service modes' characteristics mentioned above, a service system in the digital home is established to implement geographic information services on the basis of digital television. The implementation of geographic information services in the digital home not only enriches the digital home services content, but also promotes geographic information from specialization to public popularity.
... Information Retrieval Service. 950.9 Section 950.9 Commerce and Foreign Trade Regulations Relating to Commerce... Computerized Environmental Data and Information Retrieval Service. The Environmental Data Index (ENDEX... computerized, information retrieval service provides a parallel subject-author-abstract referral service. A...
Oberholzer, Hester Magdalena; Van Der Schoor, Ciska; Taute, Helena; Bester, Megan Jean
Exposure to drugs during pregnancy is a major concern, as some teratogenic compounds can influence normal foetal development. Although the use of drugs during pregnancy should generally be avoided, exposure of the developing foetus to teratogens may occur unknowingly since these compounds may be hidden in products that are being marketed as "all natural." The aim of the current study was to investigate the possible teratogenic and cellular effects of sibutramine-a serotonin-norepinephrine reuptake inhibitor used in the treatment of obesity-on the heart and liver tissue of chick embryos. Ephedrine was used as a positive control. The chick embryo model was chosen because it has been used in studying developmental and experimental biology and teratology with great success. The embryos were exposed to three different concentrations of sibutramine and ephedrine respectively. The results obtained revealed that both compounds exhibited embryotoxicity when compared to the control groups. Liver and heart tissue of the exposed embryos was severely affected by these compounds in a dose-related manner. Morphology similar to that of muscle dystrophy was observed in the heart, where the muscle tissue was infiltrated by adipose and connective tissue. Severe liver steatosis was also noted. A more in-depth investigation into the molecular pathways involved might provide more information on the exact mechanism of toxicity of these products influencing embryonic development. © 2015 Wiley Periodicals, Inc.
Feruza Khayrullaevna Sidikova
Full Text Available The main purpose of the article is investigation of the issues of development of information services and products in Uzbekistan during globalization role of information and communicative technologies in development international business and trade. As the results of the research there revealed a connection of introducing electronic commerce and business in practice of firms, corporation and banks there conducted changes in the character of carrying out commercial and financial transactions, interrelations with partners and clients, elaborations and introduction business strategies and competition itself. In the conclusion there offered the suggestions of joining and adjusting to each other varying legislation of different countries and developing international system of taxation of Internet commerce satisfying all participants of electronic trading transactions.
... COMMISSION ORGANIZATION AND FUNCTIONS § 1000.23 Office of Information and Technology Services. The Office of Information and Technology Services houses the Commission's Secretariat, which facilitates the preparation of... agency's Chief Freedom of Information Act Officer. The Office of Information and Technology Services is...
... service agents release information? 40.331 Section 40.331 Transportation Office of the Secretary of... Release of Information § 40.331 To what additional parties must employers and service agents release information? As an employer or service agent you must release information under the following circumstances...
Chae, Jeong-Pil; Park, Mi Seon; Hwang, Yoo-Seok; Min, Byung-Hwa; Kim, Sang-Hyun; Lee, Hyun-Shik; Park, Mae-Ja
Diclofenac is a non-steroidal anti-inflammatory drug (NSAID) with analgesic and anti-pyretic properties. This compound is therefore used to treat pain, inflammatory disorders, and dysmenorrhea. Due to its multimodal mechanism of action and ability to penetrate placenta, diclofenac is known to have undesirable side effects including teratogenicity. However, limited data exist on its teratogenicity, and a detailed investigation regarding harmful effects of this drug during embryogenesis is warranted. Here, we analyzed the developmental toxic effects of diclofenac using Xenopus embryos according to the Frog Embryo Teratogenesis Assay-Xenopus (FETAX) protocol. Diclofenac treatment exerted a teratogenic effect on Xenopus embryos with a teratogenic index (TI) value of 2.64 TI; if this value is higher than 1.2, the cut-off value indicative of toxicity. In particular, mortality of embryos treated with diclofenac increased in a concentration-dependent manner and a broad spectrum of malformations such as shortening and kinking of the axis, abdominal bulging, and prominent blister formation, was observed. The shape and length of internal organs also differed compared to the control group embryos and show developmental retardation on histological label. However, the expression of major tissue-specific markers did not change when analyzed by reverse transcription-polymerase chain reaction (RT-PCR). In conclusion, diclofenac treatment can promote teratogenicity that results in morphological anomalies, but not disrupt the developmental tissue arrangement during Xenopus embryogenesis. Copyright © 2014 Elsevier Ltd. All rights reserved.
Full Text Available Abstract Background Depleted uranium is being used increasingly often as a component of munitions in military conflicts. Military personnel, civilians and the DU munitions producers are being exposed to the DU aerosols that are generated. Methods We reviewed toxicological data on both natural and depleted uranium. We included peer reviewed studies and gray literature on birth malformations due to natural and depleted uranium. Our approach was to assess the "weight of evidence" with respect to teratogenicity of depleted uranium. Results Animal studies firmly support the possibility that DU is a teratogen. While the detailed pathways by which environmental DU can be internalized and reach reproductive cells are not yet fully elucidated, again, the evidence supports plausibility. To date, human epidemiological data include case examples, disease registry records, a case-control study and prospective longitudinal studies. Discussion The two most significant challenges to establishing a causal pathway between (human parental DU exposure and the birth of offspring with defects are: i distinguishing the role of DU from that of exposure to other potential teratogens; ii documentation on the individual level of extent of parental DU exposure. Studies that use biomarkers, none yet reported, can help address the latter challenge. Thoughtful triangulation of the results of multiple studies (epidemiological and other of DU teratogenicity contributes to disentangling the roles of various potentially teratogenic parental exposures. This paper is just such an endeavor. Conclusion In aggregate the human epidemiological evidence is consistent with increased risk of birth defects in offspring of persons exposed to DU.
Boxtel, Antonius L. van; Kamstra, Jorke H.; Fluitsma, Donna M.; Legler, Juliette
Dithiocarbamates (DTCs) are a class of compounds that are extensively used in agriculture as pesticides. As such, humans and wildlife are undoubtedly exposed to these chemicals. Although DTCs are thought to be relatively safe due to their short half lives, it is well established that they are teratogenic to vertebrates, especially to fish. In zebrafish, these teratogenic effects are characterized by distorted notochord development and shortened anterior to posterior axis. DTCs are known copper (Cu) chelators but this does not fully explain the observed teratogenic effects. We show here that DTCs cause malformations in zebrafish that highly resemble teratogenic effects observed by direct inhibition of a group of cuproenzymes termed lysyl oxidases (LOX). Additionally, we demonstrate that partial knockdown of three LOX genes, lox, loxl1 and loxl5b, sensitizes the developing embryo to DTC exposure. Finally, we show that DTCs directly inhibit zebrafish LOX activity in an ex vivo amine oxidase assay. Taken together, these results provide the first evidence that DTC induced teratogenic effects are, at least in part, caused by direct inhibition of LOX activity.
Gunning, D.B.; Barua, A.B.; Olson, J.A.
Retinoyl β-glucuronide, unlike retinoic acid, has been shown to be non-teratogenic when administered orally, even in large doses, to pregnant rats. The degree to which water-solubility is associated with low teratogenicity is not known. Other water-soluble forms of vitamin A have now been synthesized in our laboratory and are being evaluated for teratogenicity. New water-soluble forms of vitamin A were administered orally to pregnant Sprague-Dawley rats in a single dose of 0.35 mmole/kg bw on day 8 of gestation. On day 19, the dams were sacrificed and the litters were examined. Control animals received either vehicle only or an equivalent dose of all-trans retinoic acid. Maternal and fetal tissues were taken and analyzed by HPLC for vitamin A metabolites. In another experiment, a large single oral dose of the radiolabelled water-soluble compound was administered on day 10. At either 30 minutes or 1 hour after the dose, dams were sacrificed and the embryos analyzed both for radioactivity and for specific metabolites. In contrast to retinoyl β-glucuronide, retinoyl β-glucose is highly teratogenic under identical conditions. Thus, water-solubility does not seem to be the determining factor in the teratogenicity of retinoic acid conjugates
Knobloch, J; Jungck, D; Koch, A
Thalidomide is a teratogen that affects many organs but primarily induces limb truncations like phocomelia. Rodents are thalidomide resistant. In the 1950s, this has led to misinterpretations of animal tests and to the fatal assumption that the drug was safe for pregnant women to use against morning sickness. The result was one of the biggest scandals in medical history: 10.000 and more infants with birth defects in Europe. Nonetheless, thalidomide still has its place in modern medicine as it has strong therapeutic potential: it has been approved by the FDA for multiple myeloma and erythema nodosum leprosum, and its anti-inflammatory, immunomodulatory and antiangiogenic activities are considered in many other refractory diseases. The aim is to develop derivatives that are not teratogenic but maintain the therapeutic potential. This requires detailed knowledge about the underlying molecular mechanisms. Much progress has been made in deciphering the teratogenic mechanisms in the last decade. Here, we summarize these mechanisms, explain thalidomide resistance of rodents, and discuss possible mechanisms that could explain why the drug primarily targets the developing limb in the embryo. We also summarize the most important therapeutic mechanisms. Finally, we discuss which therapeutic and teratogenic mechanisms do and do not overlap, and if there is a chance for the development of non-teratogenic thalidomide derivatives with therapeutic potential. Copyright© Bentham Science Publishers; For any queries, please email at firstname.lastname@example.org.
Rocha, Rebeca Silveira; Bezerra, Samara Cavalcante; Lima, José Welington de Oliveira; Costa, Fabrício da Silva
Medications, alcohol and smoking can cause fetal damage. A cross-sectional study was conducted with 326 mothers of the Fortaleza General Hospital to evaluate the use of drugs, alcohol and smoking during pregnancy and its relation to teratogenic potential in different population characteristics, between 2006 and 2007. Postpartum women who had their babies in the research site were included and those whose babies were not admitted as hospital inpatients were excluded. Chi-square tests and t-tests were used in the analysis, with a p value drugs/ pregnancy) and self-medication occurred in 11.3% of the cases. Single women took more drugs with high teratogenic potential (p=0.037). 11 cases of fetal malformation were observed, five of them were exposed to high teratogenic risks. Smoking occurred in 11.3% and alcohol use in 16%. Being single was found to be a risk factor for exposure to high teratogenic potential. Quality of prenatal care and other sociodemographic variables weren't related to exposure to teratogenic risks.
Leen-Mitchell, M; Martinez, L; Gallegos, S; Robertson, J; Carey, J C
A history of the Organization of Teratology Information Services (OTIS) is presented in context of the history of teratology information services. During the late 1970s, teratology information services grew out of the need for current and accurate information about fetal effects of environmental exposures in pregnancy. Over the next decade, teratology information services networked and collaborated, developing their own professional organization. A description of the activities of OTIS is described. Copyright 2000 Wiley-Liss, Inc.
Full Text Available Enterprise Services Architecture (ESA is blueprint for now enterprise software should be constructed to provide maximum business value. The challenge facing most companies is not whether to adopt Service-Oriented Architecture (SOA, but when and how to do so. There is always a lag between technological vision and business feasibility. It also takes time to fully realize the potential of existing technologies, a process that does not stop the moment the new thing arrives. But when the value of a new approach such as ESA starts to make a difference and produces a competitive advantage, the motivation to change skyrockets. The time to change becomes now and the hunger for learning grows. The goal of this paper is to satisfy the hunger for information for those who suspect that ESA may be a gateway to transforming Information Technology (IT into a strategic weapon. This paper will explain – in more detail that ever before – what ESA is bringing the concept to life in all of its products as a platform supported by an ecosystem.
Information services provided by the Nuclear Information Centre (NIC) as the sector information centre for the Czechoslovak nuclear programme proceed primarily from its membership of INIS. From INIS Atomindex tapes are computer-processed SDI searches, their price for one query is 3,948 Czechoslovak crowns per year. The user can at any time put forward a request for tuning or for a change of the initially requested query formulation. A copy of SDI searches is provided for 1,200 Czechoslovak crowns per annum to other interested persons or institutions who cannot, however, influence the query formulation. Since 1979, the NIC has been processing retrospective searches by direct online access to the INIS data base. The price of these searches ranges between 1,000 and 1,500 Czechoslovak crowns. Under the same conditions the NIC also provides retrospective searches from AGRIS. Since 1986, the NIC has extended its services by providing data from the UVTEI-UTZ data base centre in Prague. Retrospective searches can since 1985 be processed directly at the workplace of those interested, this through mobile terminals. All said services are followed up by services provided by the NIC library which contains more than 215,000 microfiches with full texts of nonconventional documents incorporated in INIS. (Z.M.)
Kolos, S; The ATLAS collaboration; Hauser, R
The ATLAS experiment is being operated by highly distributed computing system which is constantly producing a lot of status information which is used to monitor the experiment operational conditions as well as to access the quality of the physics data being taken. For example the ATLAS High Level Trigger(HLT) algorithms are executed on the online computing farm consisting from about 1500 nodes. Each HLT algorithm is producing few thousands histograms, which have to be integrated over the whole farm and carefully analyzed in order to properly tune the event rejection. In order to handle such non-physics data the Information Service (IS) facility has been developed in the scope of the ATLAS TDAQ project. The IS provides high-performance scalable solution for information exchange in distributed environment. In the course of an ATLAS data taking session the IS handles about hundred gigabytes of information which is being constantly updated with the update interval varying from a second to few tens of seconds. IS ...
Grossi, Pablo Andrade; Souza, Leonardo Soares de; Figueiredo, Geraldo Magela; Figueiredo, Arthur
An effective management information system based on technology, information and people is necessary to improve the safety on all processes and operations subjected to radiation risks. The complex and multisource information flux from all radiation protection activities on nuclear organizations requires a robust tool/system to highlight the strengths and weaknesses and identify behaviors and trends on the activities requiring radiation protection programs. Those organized and processed data are useful to reach a successful management and to support the human decision-making on nuclear organization. This paper presents recent improvements on a management information system based on the radiation protection directives and regulations from Brazilian regulatory body. This radiation protection control system is applied to any radiation protection services and research institutes subjected to Brazilian nuclear regulation and is a powerful tool for continuous management, not only indicating how the health and safety activities are going, but why they are not going as well as planned showing up the critical points. (author)
Grossi, Pablo Andrade; Souza, Leonardo Soares de; Figueiredo, Geraldo Magela; Figueiredo, Arthur, E-mail: email@example.com, E-mail: firstname.lastname@example.org, E-mail: email@example.com, E-mail: firstname.lastname@example.org [Centro de Desenvolvimento da Tecnologia Nuclear (CDTN/CNEN-MG), Belo Horizonte, MG (Brazil)
An effective management information system based on technology, information and people is necessary to improve the safety on all processes and operations subjected to radiation risks. The complex and multisource information flux from all radiation protection activities on nuclear organizations requires a robust tool/system to highlight the strengths and weaknesses and identify behaviors and trends on the activities requiring radiation protection programs. Those organized and processed data are useful to reach a successful management and to support the human decision-making on nuclear organization. This paper presents recent improvements on a management information system based on the radiation protection directives and regulations from Brazilian regulatory body. This radiation protection control system is applied to any radiation protection services and research institutes subjected to Brazilian nuclear regulation and is a powerful tool for continuous management, not only indicating how the health and safety activities are going, but why they are not going as well as planned showing up the critical points. (author)
Karthikeyan, N; Sukanesh, R
A hospital is a health care organization providing patient treatment by expert physicians, surgeons and equipments. A report from a health care accreditation group says that miscommunication between patients and health care providers is the reason for the gap in providing emergency medical care to people in need. In developing countries, illiteracy is the major key root for deaths resulting from uncertain diseases constituting a serious public health problem. Mentally affected, differently abled and unconscious patients can't communicate about their medical history to the medical practitioners. Also, Medical practitioners can't edit or view DICOM images instantly. Our aim is to provide palm vein pattern recognition based medical record retrieval system, using cloud computing for the above mentioned people. Distributed computing technology is coming in the new forms as Grid computing and Cloud computing. These new forms are assured to bring Information Technology (IT) as a service. In this paper, we have described how these new forms of distributed computing will be helpful for modern health care industries. Cloud Computing is germinating its benefit to industrial sectors especially in medical scenarios. In Cloud Computing, IT-related capabilities and resources are provided as services, via the distributed computing on-demand. This paper is concerned with sprouting software as a service (SaaS) by means of Cloud computing with an aim to bring emergency health care sector in an umbrella with physical secured patient records. In framing the emergency healthcare treatment, the crucial thing considered necessary to decide about patients is their previous health conduct records. Thus a ubiquitous access to appropriate records is essential. Palm vein pattern recognition promises a secured patient record access. Likewise our paper reveals an efficient means to view, edit or transfer the DICOM images instantly which was a challenging task for medical practitioners in the
Laudet, Alexandre B; White, William
Substance use disorders (SUD) are, for many, chronic conditions that are typically associated with severe impairments in multiple areas of functioning. "Recovery" from SUD is, for most, a lengthy process; improvements in other areas of functioning do not necessarily follow the attainment of abstinence. The current SUD service model providing intense, short-term, symptom-focused services is ill-suited to address these issues. A recovery-oriented model of care is emerging, which provides coordinated recovery-support services using a chronic-care model of sustained recovery management. Information is needed about substance users' priorities, particularly persons in recovery who are not currently enrolled in treatment, to guide the development of recovery-oriented systems. As a first step in filling this gap, we present qualitative data on current life priorities among a sample of individuals that collectively represent successive recovery stages (N = 356). Findings suggest that many areas of functioning remain challenging long after abstinence is attained, most notably employment and education, family/social relations, and housing. Although the ranking of priorities changes somewhat across recovery stages, employment is consistently the second most important priority, behind working on one's recovery. Study limitations are noted, and the implications of findings for the development and evaluation of recovery-oriented services are discussed.
Full Text Available STMIK AMIKOM Purwokerto merupakan salah satu perguruan tinggi swasta yang dalam proses pengelolaan dan penyampaian informasi telah menerapan teknologi informasi. Proses pelayanan suatu perguruan tinggi dipandang sebagai suatu solusi yang nantinya dapat meningkatkan kemampuan perusahaan di dalam pelayanan. Hal ini menyebabkan pentingnya peningkatan peran teknologi informasi agar selaras dengan investasi baik hardware dan software yang dikeluarkan, sehingga dibutuhkan perencanaan yang optimal.IT Service Management (ITSM digunakan sebagai upaya untuk meningkatkan efisiensi pelayanan teknologi informasi kepada pengguna yang terdapat dalam framework Information Technology Infrastructure Library.Diharapkan dengan penerapan ITSM pengelolaan layanan TI menjadi lebih baik serta mampu menyelesaikan beberapa permasalahan yang ada pada organisasiyang sedang berjalan dengan menggunakan COBIT 4.1. ITSM menghasilkan perancangan pada masing-masing prosesnya dari 2 domain pembangun ITSM yaitu domain service support dan service delivery. Kata Kunci: ITSM, ITIL V3, COBIT 4.1
models. The application of westernised approaches to service companies that operate .... (2009), who investigated the relationship between the marketing ... customer satisfaction and service quality is the primary goal of service firms that want.
... DEPARTMENT OF TRANSPORTATION Research & Innovative Technology Administration [Docket ID Number RITA 2008-0002] Agency Information Collection; Activity Under OMB Review: Airline Service Quality.... SUPPLEMENTARY INFORMATION: OMB Approval No. 2138-0041 Title: Airline Service Quality Performance -Part 234. Form...
...-NEW] Agency Information Collection Activities: Online Survey of Web Services Employers; New... information collection. (2) Title of the Form/Collection: Online Survey of Web Services Employers. (3) Agency... USCIS obtains data on the E-Verify Program Web Services. Gaining an understanding of the Web Services...
Fang, Hongliang; Beaudoing, Hiroko K.; Mocko, David M.; Rodell, Matthew; Teng, Bill; Vollmer, Bruce
Terrestrial hydrological variables are important in global hydrology, climate, and carbon cycle studies. The North American and Global Land Data Assimilation Systems (NLDAS and GLDAS, respectively) have been generating a series of land surface states (soil moisture, snow, and temperature) and fluxes (evapotranspiration, radiation, and heat flux) variables. These data, hosted at and available from NASA s Hydrology Data and Information Services Center (HDISC), include the NLDAS hourly 1/8 degree products and the GLDAS 3-hourly 0.25 and 1.0 degree products. HDISC provides easy access and visualization and analysis capabilities for these products, thus reducing the time and resources spent by scientists on data management and facilitating hydrological research. Users can perform spatial and parameter subsetting, data format transformation, and data analysis operations without needing to first download the data. HDISC is continually being developed as a data and services portal that supports weather and climate forecasts, and water and energy cycle research.
Full Text Available Counselling or prescribing drugs during pregnancy requires health professionals to assess risk/benefit ratio for women and their baby. A misperception of the risk may lead to inappropriate decisions for pregnancy outcomes. The aim of the present study was to assess teratogenic and/or foetotoxic risk perception of common medications by general practitioners (GPs and community pharmacists (CPs from the Midi-Pyrenees area.Methods: 103 GPs and 104 CPs were interviewed. For 21 given drugs, a visual-analogue scale was used to evaluate the risk to give birth to a malformed infant if the mother had taken the drug during first trimester of pregnancy. For 9 drugs, health professionals had to say if they thought there was a potential foetotoxic and/or neonatal risk when drugs were administered during late pregnancy.Results: 97% and 91% of GPs and CPs respectively thought that isotretinoin and thalidomide are teratogenic and more than 80% thought that amoxicillin and acetaminophen are safe in early pregnancy. However, 19% of the GPs and 33% of CPs answered there were no teratogenic risk for valproate. Around 11% of both GPs and CPs said that warfarin was safe during pregnancy. For 22% of GPs and for 13% and 27% of CPs respectively, ibuprofen and enalapril were safe on late pregnancy. For each drug, mean value of perceived teratogenic risk by health professionals was higher than values that can be found in scientific references. Concerning isotretinoin, thalidomide and metoclopramide, perceived teratogenic risk was higher for CPs.Conclusion: These data show that the potential teratogenic and foetotoxic risk of several commonly used drugs is unknown by health professionals. Conversely, GPs and CPs who think that a risk exists, overestimate it. This misperception can lead to inappropriate decisions for pregnancy outcomes.
Li, Dan; Liu, Mengyun; Yang, Yongsheng; Shi, Huahong; Zhou, Junliang; He, Defu
Agricultural chemical inputs have been considered as a risk factor for the global declines in amphibian populations, yet the application of agricultural fungicides has increased dramatically in recent years. Currently little is known about the potential toxicity of fungicides on the embryos of amphibians. We studied the effects of ten commonly used fungicides (four strobilurins, two SDHIs, two triazoles, fludioxonil and folpet) on Xenopus tropicalis embryos. Lethal and teratogenic effects were respectively examined after 48 h exposure. The median lethal concentrations (LC50s) and the median teratogenic concentrations (TC50s) were determined in line with actual exposure concentrations. These fungicides except two triazoles showed obvious lethal effects on embryos; however LC50s of four strobilurins were the lowest and in the range of 6.81–196.59 μg/L. Strobilurins, SDHIs and fludioxonil induced severe malformations in embryos. Among the ten fungicides, the lowest TC50s were observed for four strobilurins in the range of 0.61–84.13 μg/L. The teratogenicity shared similar dose–effect relationship and consistent phenotypes mainly including microcephaly, hypopigmentation, somite segmentation and narrow fins. The findings indicate that the developmental toxicity of currently-used fungicides involved with ecologic risks on amphibians. Especially strobilurins are highly toxic to amphibian embryos at μg/L level, which is close to environmentally relevant concentrations. - Highlights: • Effects of ten agricultural fungicides were tested on Xenopus tropicalis embryos. • Strobilurin fungicides showed strong lethal and teratogenic effects on embryos. • Lowest LC50 and TC50 were observed for strobilurins in ten fungicides. • μg/L level of toxic concentrations for strobilurins was environmentally relevant. • Teratogenicity shared similar dose–effect relationship and main phenotypes. - Strobilurins induced strong lethality and teratogenicity on Xenopus
Full Text Available The unprecedented incertitude existing in the health system in Romaniaimplies menaces for the system managers. The improvement of theperformance of the medical system has never been more adequate, so thatthe health system needs specific managerial strategies. Romania needs acomplete solution which could assure a performant management of themedical information in the system, and in their plans, the managers of thehealthcare organizations must include investments for the application of theinformational technologies, like the administration of medical information, ofthe health electronic file, the medical information exchange, so that themedical service be continuous and permanent from the birth until the death ofany individual. But the piece of information is only valuable to the one whoknows how to use it, where to search for it, how to choose it and finally howto use it, so that we can say the main instrument to which the manager fromthe health system may resort rapidly in order to find new solutions isinformation.
direct questions to me at (703) 601-5868 (DSN 329-5868). t ~a/J1~ Patricia A. Marsh, CPA Assistant Inspector General Defense Business Operations ...incrcment. Additionally, a Managemen t Control Matrix has been ~ubmillcd tor the BEIS FllrTlily o( System!! on an annual basis 6ince 2006. POg< l of4...including suggestions for reducing this burden, to Washington Headquarters Services, Directorate for Information Operations and Reports, 1215
Houser, Paul R. [CREW Services LLC, Ellicott City, MD (United States)
The Land Information System (LIS) was developed to use advanced flexible land surface modeling and data assimilation frameworks to integrate extremely large satellite- and ground-based observations with advanced land surface models to produce continuous high-resolution fields of land surface states and fluxes. The resulting fields are extremely useful for drought and flood assessment, agricultural planning, disaster management, weather and climate forecasting, water resources assessment, and the like. We envisioned transforming the LIS modeling system into a scientific cloud computing-aware web and data service that would allow clients to easily setup and configure for use in addressing large water management issues. The focus of this Phase 1 project was to determine the scientific, technical, commercial merit and feasibility of the proposed LIS-cloud innovations that are currently barriers to broad LIS applicability. We (a) quantified the barriers to broad LIS utility and commercialization (high performance computing, big data, user interface, and licensing issues); (b) designed the proposed LIS-cloud web service, model-data interface, database services, and user interfaces; (c) constructed a prototype LIS user interface including abstractions for simulation control, visualization, and data interaction, (d) used the prototype to conduct a market analysis and survey to determine potential market size and competition, (e) identified LIS software licensing and copyright limitations and developed solutions, and (f) developed a business plan for development and marketing of the LIS-cloud innovation. While some significant feasibility issues were found in the LIS licensing, overall a high degree of LIS-cloud technical feasibility was found.
This paper analyzes the effect of the network environment on the uranium mining and metallurgy of the information service. Introduces some measures such as strengthening professional characteristic literature resources construction, changing the service mode, building up information navigation, deepening service, meet the individual needs of users, raising librarian's quality, promoting the co-construction and sharing of library information resources, and puts forward the development idea of uranium mining and metallurgy library information service under the network environment. (author)
Burkhardt, Laura; Masotto, Tom; Sims, J. Terry; Whittredge, Roy; Alger, Linda S.
The purpose is to document the functional requirements and detailed specifications for the Inter-Computer Communications Services (ICCS) of the Advanced Information Processing System (AIPS). An introductory section is provided to outline the overall architecture and functional requirements of the AIPS and to present an overview of the ICCS. An overview of the AIPS architecture as well as a brief description of the AIPS software is given. The guarantees of the ICCS are provided, and the ICCS is described as a seven-layered International Standards Organization (ISO) Model. The ICCS functional requirements, functional design, and detailed specifications as well as each layer of the ICCS are also described. A summary of results and suggestions for future work are presented.
Camara, Gaoussou; Diallo, Al Hassim; Lo, Moussa; Tendeng, Jacques-Noël; Lo, Seynabou
In Senegal, great amounts of data are daily generated by medical activities such as consultation, hospitalization, blood test, x-ray, birth, death, etc. These data are still recorded in register, printed images, audios and movies which are manually processed. However, some medical organizations have their own software for non-standardized patient record management, appointment, wages, etc. without any possibility of sharing these data or communicating with other medical structures. This leads to lots of limitations in reusing or sharing these data because of their possible structural and semantic heterogeneity. To overcome these problems we have proposed a National Medical Information System for Senegal (SIMENS). As an integrated platform, SIMENS provides an EHR system that supports healthcare activities, a mobile version and a web portal. The SIMENS architecture proposes also a data and application integration services for supporting interoperability and decision making.
Buontempo, Carlo; Hewitt, Chris
Societies have always faced challenges and opportunities arising from variations in climate, and have often flourished or collapsed depending on their ability to adapt to such changes. Recent advances in our understanding and ability to forecast climate variability and climate change have meant that skilful predictions are beginning to be routinely made on seasonal to decadal (s2d) timescales. Such forecasts have the potential to be of great value to a wide range of decision-making, where outcomes are strongly influenced by variations in the climate. The European Commission have recently commissioned a major four year long project (EUPORIAS) to develop prototype end-to-end climate impact prediction services operating on a seasonal to decadal timescale, and assess their value in informing decision-making. EUPORIAS commenced on 1 November 2012, coordinated by the UK Met Office leading a consortium of 24 organisations representing world-class European climate research and climate service centres, expertise in impacts assessments and seasonal predictions, two United Nations agencies, specialists in new media, and commercial companies in climate-vulnerable sectors such as energy, water and tourism. The paper describes the setup of the project, its main outcome and some of the very preliminary results.
... DEPARTMENT OF THE TREASURY Fiscal Service Financial Management Service; Proposed Collection of Information: Direct Deposit Sign-Up Form AGENCY: Financial Management Service, Fiscal Service, Treasury. ACTION: Notice and Request for comments. SUMMARY: The Financial Management Service, as part of its...
... DEPARTMENT OF THE TREASURY Fiscal Service Financial Management Service Proposed Collection of Information: CMIA Annual Report and Direct Cost Claims AGENCY: Financial Management Service, Fiscal Service, Treasury. ACTION: Notice and request for comments. SUMMARY: The Financial Management Service, as part of...
Chen, Nengcheng; E, Dongcheng; Di, Liping; Gong, Jianya; Chen, Zeqiang
In order to improve the access precision of polar geospatial information service on web, a new methodology for retrieving global spatial information services based on geospatial service search and ontology reasoning is proposed, the geospatial service search is implemented to find the coarse service from web, the ontology reasoning is designed to find the refined service from the coarse service. The proposed framework includes standardized distributed geospatial web services, a geospatial service search engine, an extended UDDI registry, and a multi-protocol geospatial information service client. Some key technologies addressed include service discovery based on search engine and service ontology modeling and reasoning in the Antarctic geospatial context. Finally, an Antarctica multi protocol OWS portal prototype based on the proposed methodology is introduced.
Yan, Yu-Hua; Kung, Chih-Ming; Fang, Shih-Chieh; Chen, Yi
This study analyzed differences between transparency of information disclosure and related demands from the health service consumer's perspective. It also compared how health service providers and consumers are associated by different levels of mandatory information disclosure. We obtained our research data using a questionnaire survey (health services providers, n = 201; health service consumers, n = 384). Health service consumers do not have major concerns regarding mandatory information disclosure. However, they are concerned about complaint channels and settlement results, results of patient satisfaction surveys, and disclosure of hospital financial statements ( p transparency of information disclosure ( p information provided by hospitals. Thus, when a hospital discloses information, it is necessary for the government to consider the information's applicability. Toward improving medical expertise and information asymmetry, the government has to reduce the burden among health service consumers in dealing with this information, and it has to use the information effectively.
'Mopera' information service is a mobile information service in which NTT Mobile Communications Network, Inc. offers information of various fields such as business and hobbies for the users of the portable telephone or PHS of the company. Toshiba Corp. started the contents operation center consistently performing from the preparation of contents to the management of a server for the above information service, making efforts in expanding the contents since the beginning of the service in the fall of 1998, and operating at present more than ten kinds of contents such as news, weather forecast, and stock information other than mobile 'Ekimae-Tanken Club' (adventure club in front of a station). Moreover, Toshiba takes it into consideration to build a system aiming at a stable operation like a duplex operation of a server, 24-hour automatic surveillance, etc., continuously providing highly reliable services. (translated by NEDO)
Schroeder, M.; Stender, V.; Jüngling, S.
Leptoukh, G. G.; Alcott, G. T.; Kempler, S. J.; Lynnes, C. S.; Vollmer, B. E.
The NASA Goddard Earth Sciences Data and Information Services Center (GES DISC), in addition to serving the Earth Science community as one of the major Distributed Active Archive Centers (DAACs), provides much more than just data. Among the value-added services available to general users are subsetting data spatially and/or by parameter, online analysis (to avoid downloading unnecessary all the data), and assistance in obtaining data from other centers. Services available to data producers and high-volume users include consulting on building new products with standard formats and metadata and construction of data management systems. A particularly useful service is data processing at the DISC (i.e., close to the input data) with the users' algorithms. This can take a number of different forms: as a configuration-managed algorithm within the main processing stream; as a stand-alone program next to the on-line data storage; as build-it-yourself code within the Near-Archive Data Mining (NADM) system; or as an on-the-fly analysis with simple algorithms embedded into the web-based tools. Partnerships between the GES DISC and scientists, both producers and users, allow the scientists concentrate on science, while the GES DISC handles the of data management, e.g., formats, integration and data processing. The existing data management infrastructure at the GES DISC supports a wide spectrum of options: from simple data support to sophisticated on-line analysis tools, producing economies of scale and rapid time-to-deploy. At the same time, such partnerships allow the GES DISC to serve the user community more efficiently and to better prioritize on-line holdings. Several examples of successful partnerships are described in the presentation.
McShane, Lesley; Greenwell, Kate; Corbett, Sally; Walker, Richard
People with long-term conditions need to be signposted to high quality information and advice to understand and manage their condition. Information seeking tools combined with third sector information could help address their information needs. To describe the development and implementation of an information service for people living with long-term conditions at one NHS acute trust in the Northeast of England. An information service was trialled using bespoke information models for three long-term conditions in collaboration with third sector organisations. These guided people to relevant, timely and reliable information. Both clinician and service user questionnaires were used to evaluate satisfaction with the service. Appropriately designed information models can be used interchangeably across all services. Between 75% and 91% of users agreed that they were satisfied with various aspects of the service. Generally, users received relevant, understandable and high quality information at the right time. Nearly all health professionals (94-100%) felt the service was accessible, provided high quality information and did not significantly impact on their consultation time. The developed information service was well received by service users and health professionals. Specifically, the use of information prescriptions and menus facilitated access to information for people with long-term conditions. © 2014 The authors. Health Information and Libraries Journal © 2014 Health Libraries Group.
Hancock, Rebecca L; Ungar, Wendy J; Einarson, Adrienne; Goodstadt, Michael; Koren, Gideon
Teratology Information Services (TIS) provide information on exposures during pregnancy and breast-feeding. Maintaining ongoing funding is a challenge. The purpose was to gather descriptive information on current TIS operations. All North American TIS (16 American, 2 Canadian) completed a detailed survey. Service goal ranked as most important was correction of risk misperceptions. Inquiries were primarily for medications (mean 43.5%, S.D. 14.1), lactation exposures, and workplace exposures. Median employees per TIS: three (range 1-12.5). Two TIS only counsel health care professionals (HCPs). Main callers to remaining TIS were pregnant women (mean 46.8%, S.D. 22.8), physicians, and nurses. Calls per week varied (median 20, range 4-600). Median annual budget: US dollars 69,000 (range dollars 3000-335,000). Seventeen TIS collect patient data for research. This survey was the first to document TIS operations in North America and demonstrates a spectrum of clinical and research activities, and provides data for a future cost-benefit analysis of TIS.
Full Text Available Information Technology (IT is increasingly progressing. Nowadays, the success of a business of the organization/company is highly dependent on the IT infrastructure used. Therefore, organizations/companies have to manage their IT service to be optimal to their customers. Looking at this matter and the increasing dynamics of XYZ University, then Data and Information System Center (Pusdatin - an IT provider of XYZ University began implementing IT Service Management (ITSM from 2013 using the latest version of Information Technology Infrastructure Library (ITIL, namely ITIL v3 as a framework for implementing ITSM in its business processes. However, along the way, there are still some problems happen in Pusdatin in order that ITSM can actually support and align with the objectives of XYZ University. Through this paper, the authors want to explain how the implementation of ITSM at Pusdatin, identify the problems related to the implementation of ITSM, and provide the solutions for each problem. The methods used are direct observation to Pusdatin, conductan interview with the Head of Pusdatin and Staff of Pusdatin, and also perform a literature review of books and papers that discuss about ITIL. The result of this research is that ITSM process of Pusdatin generally works quite well but there are still some shortcomings because ITSM is not 100% implemented in all areas.
The International Nuclear Information System (INIS) provides links to useful nuclear related information sources in Internet by the name of 'INIS Web Services' and the Energy Technology Data Exchange (ETDE) also provides links to useful energy related information sources in Internet by the name of Energy Information Source'. This paper outlines these two services. (author)
Nelson, F. Howard; Bailey, Bernadette
Provides a history of the American Federation of Teachers (AFT) union and its information services and research functions. Examines the research department and the influence of technology, shifting from collecting information to using information from the Internet and online databases that has made access easier. Analyzes information services with…
Gelder, M.M.H.J. van; Jong-van den Berg, L.T. de; Roeleveld, N.
STUDY QUESTION: What is the current state of knowledge on the human risks of drugs suspected to be associated with teratogenic mechanisms? SUMMARY ANSWER: Evidence for the presence or absence of human risks of birth defects is scarce or non-existent for the majority of drugs associated with
Milligan, J. E.; And Others
Pregnant women, especially those working in veterinary medicine, face occupational health/disease risks from mutagens, teratogens, and carcinogens. These hazards can be placed into three categories: physical, chemical, and biological. Each of these hazards is discussed with examples. (Author/JN)
Background Anticonvulsants have been used to manage psychiatric conditions for over 50 years. It is recognised that some, particularly valproate, carbamazepine and lamotrigine, are human teratogens, while others including topiramate require further investigation. We aimed to appraise the documentation of this risk by psychiatrists and review discussion around contraceptive issues. Methods A retrospective review of prescribing patterns of four anticonvulsants (valproate, carbamazepine, lamotrigine and topiramate) in women of child bearing age was undertaken. Documented evidence of discussion surrounding teratogenicity and contraceptive issues was sought. Results Valproate was most commonly prescribed (n=67). Evidence of teratogenic risk counselling at medication initiation was sub-optimal – 40% of individuals prescribed carbamazepine and 22% of valproate. Documentation surrounding contraceptive issues was also low- 17% of individuals prescribed carbamazepine and 13% of valproate. Conclusion We found both low rates of teratogenic risk counselling and low rates of contraception advice in our cohort. Given the high rates of unplanned pregnancies combined with the relatively high risk of major congenital malformations, it is essential that a detailed appraisal of the risks and benefits associated with anticonvulsant medication occurs and is documented within patients’ psychiatric notes. PMID:24066860
Kammann, Ulrike; Biselli, Scarlett; Huehnerfuss, Heinrich; Reineke, Ninja; Theobald, Norbert; Vobach, Michael; Wosniok, Werner
Organic extracts of marine sediments from the North Sea and the Baltic Sea were investigated with two toxicity assays. The comet assay based on the fish cell line Epithelioma papulosum cyprini (EPC) was applied to determine the genotoxic potential; zebrafish embryos (Danio rerio) were used to quantify the teratogenic potential of the samples. EC 50 values were calculated from dose-response curves for both test systems. Highest teratogenic and genotoxic effects normalised to total organic carbon (TOC) content were detected in sediment samples of different origins. Polychlorinated biphenyls (PCBs) and polycyclic aromatic hydrocarbons (PAHs) are not likely to be the causes of the observed effects, as demonstrated by a two-step fractionation procedure of selected extracts. The toxic potential was more pronounced in fractions having polarity higher than those possessed by PAHs and PCBs. The suitability of the two in vitro test systems for assessing genotoxic and teratogenic effects of marine sediment extracts could be demonstrated. - Capsule: In vitro toxicity assays are used to assess genotoxic and teratogenic effects of environmental extracts
Zhu, Jingmin; Janesick, Amanda; Wu, Lijiao; Hu, Lingling; Tang, Weiyi; Blumberg, Bruce; Shi, Huahong
The RXR agonist (triphenyltin, TPT) and the RXR antagonist (UVI3003) both show teratogenicity and, unexpectedly, induce similar malformations in Xenopus tropicalis embryos. In the present study, we exposed X. tropicalis embryos to UVI3003 in seven specific developmental windows and identified changes in gene expression. We further measured the ability of UVI3003 to activate Xenopus RXRα (xRXRα) and PPARγ (xPPARγ) in vitro and in vivo. We found that UVI3003 activated xPPARγ either in Cos7 cells (in vitro) or Xenopus embryos (in vivo). UVI3003 did not significantly activate human or mouse PPARγ in vitro; therefore, the activation of Xenopus PPARγ by UVI3003 is novel. The ability of UVI3003 to activate xPPARγ explains why UVI3003 and TPT yield similar phenotypes in Xenopus embryos. Our results indicate that activating PPARγ leads to teratogenic effects in Xenopus embryos. More generally, we infer that chemicals known to specifically modulate mammalian nuclear hormone receptors cannot be assumed to have the same activity in non-mammalian species, such as Xenopus. Rather they must be tested for activity and specificity on receptors of the species in question to avoid making inappropriate conclusions. - Highlights: • UVI3003 is a RXRs antagonist and shows teratogenicity to Xenopus embryos. • UVI3003 activated xPPARγ either in Cos7 cells or Xenopus embryos. • UVI3003 did not activate human or mouse PPARγ in Cos7 cells. • Activating PPARγ leads to teratogenic effects in Xenopus embryos.
Jen, Wen-Yuan; Chao, Chia-Chen; Hung, Ming-Chien; Li, Yu-Chuan; Chi, Y P
Most healthcare providers provide mobile service for their medical staff; however, few healthcare providers provide mobile service as part of their outpatient service. The mobile outpatient service system (MOSS) focuses on illness treatment, illness prevention and patient relation management for outpatient service users. Initiated in a local hospital in Taiwan, the MOSS pilot project was developed to improve outpatient service quality and pursue higher patient safety. This study focuses on the development of the MOSS. The workflow, architecture and target users of the MOSS are delineated. In addition, there were two surveys conducted as part of this study. After a focus group of medical staff identified areas in which outpatient services might be improved by the MOSS, the first survey was administered to outpatients to confirm the focus group's intuitions. The second administration of the survey explored outpatient satisfaction after they used the MOSS service. With regard to outpatient attitudes, about 93% of participants agreed that the mobile outpatient service improved outpatient service quality. In the area of outpatient satisfaction, about 89% of participants indicated they were satisfied with the mobile outpatient service. Supported by our study finding, we propose that more diverse mobile outpatient services can be provided in the future.
Korosec, D.; Vojvodic Tuma, J.
In the present paper, the aspects of Risk Informed In-Service Inspection (RI-ISI) are discussed. Slovenian Nuclear Safety Administration (SNSA) and its authorized organization for the ISI activities, Institute of Metals and Technologies (IMT), are actually permanently involved in the ISI processes of the nuclear power plant (NPP) Krsko. Based on the previous experience on the ISI activities, evaluation of the results and review of the existing practice in nuclear world, the activities are started to asses the piping of systems in the light of probability of failure. This is so called Risk Informed approach. By the design established criteria, standards and practice gives good fundaments for the improvements implementation. Improvements can be done on the way that the more broad knowledge about safety important components of the systems shall bee added to the basic practice. It is necessary to identify conditions of the safety important components, such as realistic stress and fatigue conditions, material properties changes due aging processes, the temperature cycling effects, existing flaws characterization in the light of the previous detection and equipment technique used, assessment of the measurement accuracy on the results etc. In addition to this deterministic approach, the principles of risk evaluation methods should be used. NPP Krsko has, as practically majority of NPP's, probabilistic risk assessment (PRA) studies for all safety important systems and components. The methods and results from these studies can be efficiently used to upgrade classical deterministic results, based on which the in-service program as a whole is usually done. In addition to the above mentioned, risk assessment and evaluation of the piping shall be done, which is not covered by the existing PRA analysis. To do this it is necessary to made risk evaluation of the piping segments, based on previous structural element probability assessment. Probabilistic risk assessment is important
Widener, Patrick M. [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States). Scalable System Software Dept.
Exascale data environments are fast approaching, driven by diverse structured and unstructured data such as system and application telemetry streams, open-source information capture, and on-demand simulation output. Storage costs having plummeted, the question is now one of converting vast stores of data to actionable information. Complicating this problem are the low degrees of awareness across domain boundaries about what potentially useful data may exist, and write-once-read- never issues (data generation/collection rates outpacing data analysis and integration rates). Increasingly, technologists and researchers need to correlate previously unrelated data sources and artifacts to produce fused data views for domain-specific purposes. New tools and approaches for creating such views from vast amounts of data are vitally important to maintaining research and operational momentum. We propose to research and develop tools and services to assist in the creation, refinement, discovery and reuse of fused data views over large, diverse collections of heterogeneously structured data. We innovate in the following ways. First, we enable and encourage end-users to introduce customized index methods selected for local benefit rather than for global interaction (flexible multi-indexing). We envision rich combinations of such views on application data: views that span backing stores with different semantics, that introduce analytic methods of indexing, and that define multiple views on individual data items. We specifically decline to build a big fused database of everything providing a centralized index over all data, or to export a rigid schema to all comers as in federated query approaches. Second, we proactively advertise these application-specific views so that they may be programmatically reused and extended (data proactivity). Through this mechanism, both changes in state (new data in existing view collected) and changes in structure (new or derived view exists) are
Widener, Patrick [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)
Exascale data environments are fast approaching, driven by diverse structured and unstructured data such as system and application telemetry streams, open-source information capture, and on-demand simulation output. Storage costs having plummeted, the question is now one of converting vast stores of data to actionable information. Complicating this problem are the low degrees of awareness across domain boundaries about what potentially useful data may exist, and write-once- read-never issues (data generation/collection rates outpacing data analysis and integration rates). Increasingly, technologists and researchers need to correlate previously unrelated data sources and artifacts to produce fused data views for domain-specific purposes. New tools and approaches for creating such views from vast amounts of data are vitally important to maintaining research and operational momentum. We propose to research and develop tools and services to assist in the creation, refinement, discovery and reuse of fused data views over large, diverse collections of heterogeneously structured data. We innovate in the following ways. First, we enable and encourage end-users to introduce customized index methods selected for local benefit rather than for global interaction (flexible multi-indexing). We envision rich combinations of such views on application data: views that span backing stores with different semantics, that introduce analytic methods of indexing, and that define multiple views on individual data items. We specifically decline to build a big fused database of everything providing a centralized index over all data, or to export a rigid schema to all comers as in federated query approaches. Second, we proactively advertise these application-specific views so that they may be programmatically reused and extended (data proactivity). Through this mechanism, both changes in state (new data in existing view collected) and changes in structure (new or derived view exists) are
This document presents information regarding data collection and dissemination functions for traveler information services in rural areas. It documents data collection functions and information dissemination functions, and provides an interpretive de...
... Information: Electronic Transfer Account (ETA) Financial Agency Agreement AGENCY: Financial Management Service... of information described below: Title: Electronic Transfer Account (ETA) Financial Agency Agreement... public and other Federal agencies to take this opportunity to comment on a continuing information...
Yoo, H. J.; Choi, S. N.; Kim, H. N.; Kim, Y. H.; Yang, S. H.
The iSTMS is a web-based integrated information system supporting Pre-Service and In-Service Inspection(PSI/ISI) processes for the nuclear power plants of KHNP(Korea Hydro and Nuclear Power Co. Ltd.). The system provides a full spectrum coverage of the inspection processes from the planning stage to the final report of examination in accordance with applicable codes, standards, and regulatory requirements. The major functions of the system includes the inspection planning, examination, reporting, project control and status reporting, resource management as well as objects search and navigation. The system also provides two dimensional or three dimensional visualization interface to identify the location and geometry of components and weld areas subject to examination in collaboration with database applications. The iSIMS is implemented with commercial software packages such as database management system, 2-D and 3-D visualization tool, etc., which provide open, updated and verified foundations. This paper describes the key functions and the technologies for the implementation of the iSIMS
Yoo, H. J.; Choi, S. N.; Kim, H. N.; Kim, Y. H.; Yang, S. H. [Korea Electric Power Research Institute, Daejeon (Korea, Republic of)
The iSTMS is a web-based integrated information system supporting Pre-Service and In-Service Inspection(PSI/ISI) processes for the nuclear power plants of KHNP(Korea Hydro and Nuclear Power Co. Ltd.). The system provides a full spectrum coverage of the inspection processes from the planning stage to the final report of examination in accordance with applicable codes, standards, and regulatory requirements. The major functions of the system includes the inspection planning, examination, reporting, project control and status reporting, resource management as well as objects search and navigation. The system also provides two dimensional or three dimensional visualization interface to identify the location and geometry of components and weld areas subject to examination in collaboration with database applications. The iSIMS is implemented with commercial software packages such as database management system, 2-D and 3-D visualization tool, etc., which provide open, updated and verified foundations. This paper describes the key functions and the technologies for the implementation of the iSIMS
..., Miscellaneous customer service and informational expenses. 367.9100 Section 367.9100 Conservation of Power and... Account 910, Miscellaneous customer service and informational expenses. (a) This account must include the cost of labor, materials used and expenses incurred in connection with customer service and...
... RITA 2008-0002] Agency Information Collection; Activity Under OMB Review; Airline Service Quality... Reports'' pursuant to 14 CFR 234.4 and 234.6. These reports are used to monitor the quality of air service.... SUPPLEMENTARY INFORMATION: OMB Approval No. 2138-0041. Title: Airline Service Quality Performance--Part 234...
... 2008-0002] Agency Information Collection; Activity Under OMB Review; Airline Service Quality...'' pursuant to 14 CFR 234.4 and 234.6. These reports are used to monitor the quality of air service that... INFORMATION: OMB Approval No. 2138-0041. Title: Airline Service Quality Performance Reports--Part 234. Form No...
... amounts for volunteers, as explained at 75 FR 18752, and Centralized Billing Service Providers (CBSPs), as... Information Services Division; Revised User Fee Schedule AGENCY: Federal Bureau of Investigation (FBI.... Enourato, Section Chief, Resources Management Section, Criminal Justice Information Services Division, FBI...
... mental health services. 51.46 Section 51.46 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND... a provider of mental health services. (a) Except as provided in paragraph (b) of this section, if a... of mental health services, it may not disclose information from such records to the individual who is...
... 25 Indians 1 2010-04-01 2010-04-01 false What information is contained in a social services assessment? 20.404 Section 20.404 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT OF THE INTERIOR HUMAN SERVICES FINANCIAL ASSISTANCE AND SOCIAL SERVICES PROGRAMS Services to Children, Elderly, and Families § 20.404 What...
... Request; Quarterly Survey of Financial Services Transactions Between U.S. Financial Services Providers [email protected] . SUPPLEMENTARY INFORMATION: I. Abstract Form BE-185, Quarterly Survey of Financial Services Transactions between U.S. Financial Services Providers and Foreign Persons, obtains quarterly data from U.S...
Ashrafi-Rizi, Hasan; Kazempour, Zahra
Marketing is one of the essential parts of any business corporation in the modern management. One can see the difference between corporations in gaining their goals, considering their marketing methods. Gaining more advantage or acquiring more funds can be of reasons for marketing, but these are not all the reasons. Perhaps the most important reason for marketing is increasing the customer satisfaction. This, in turn, leads to more willingness in payment and using services. Nowadays, due to rapid growth in ICT, changes in budgets, rapid growth in development and use of knowledge, variety of users and their needs, marketing has become an important factor in any library activities. Libraries are now more responsible in this regard, because marketing is now an important tool in improving users' satisfaction in using library services. Hence, marketing is now very important for libraries to survive in the increasing pressures of competitive conditions of the information market. This article is tapping on issues such as information marketing, principles of marketing, marketing techniques, developing markets, and marketing skills. Some recommendations are also presented for marketing in libraries.
Ashrafi-rizi, Hasan; Kazempour, Zahra
Marketing is one of the essential parts of any business corporation in the modern management. One can see the difference between corporations in gaining their goals, considering their marketing methods. Gaining more advantage or acquiring more funds can be of reasons for marketing, but these are not all the reasons. Perhaps the most important reason for marketing is increasing the customer satisfaction. This, in turn, leads to more willingness in payment and using services. Nowadays, due to rapid growth in ICT, changes in budgets, rapid growth in development and use of knowledge, variety of users and their needs, marketing has become an important factor in any library activities. Libraries are now more responsible in this regard, because marketing is now an important tool in improving users’ satisfaction in using library services. Hence, marketing is now very important for libraries to survive in the increasing pressures of competitive conditions of the information market. This article is tapping on issues such as information marketing, principles of marketing, marketing techniques, developing markets, and marketing skills. Some recommendations are also presented for marketing in libraries. PMID:23555112
Goldman, C.; Kempton, W.; Eide, A.; Iyer, M. [and others
This study analyzes the potential impact of information and communications technologies on utility delivery of residential customer energy services. Many utilities are conducting trials which test energy-related and non-energy services using advanced communications systems.
... services projects and the state-of-the-art processes through which projects are implemented. The survey will gather information concerning: Methods used in ecosystem services projects, motivations for...
... DEPARTMENT OF EDUCATION Office of Special Education and Rehabilitative Services; Overview Information; Special Demonstration Programs--Model Demonstration Projects To Improve Outcomes for Individuals.... Alexa Posny, Assistant Secretary for Special Education and Rehabilitative Services. [FR Doc. 2010-19585...
Bass, Tim; Donahue, William
Service-oriented architecture (SOA), a term often used today in conjunction with net-centric operations, implies that existing and future DoD information capabilities will be engineered to publish product and/or service offerings...
... (Veterans Transportation Service Data Collection); Activity: Comment Request AGENCY: Veterans Health.... This notice solicits comments on the information needed to evaluate the Veterans Transportation Service... receive timely and reliable transportation for the purpose of examination, treatment and care. DATES...
Schadow, Gunther; Dhaval, Rakesh; McDonald, Clement J; Ragg, Susanne
We present the architecture and approach of an evolving campus-wide information service for tissues with clinical and data annotations to be used and contributed to by clinical researchers across the campus. The services provided include specimen tracking, long term data storage, and computational analysis services. The project is conceived and sustained by collaboration among researchers on the campus as well as participation in standards organizations and national collaboratives.
Schumann, Sebastian; Mikoczy, Eugen; Podhradsky, Pavol; Muruchi, Feliciano; Maruschke, Michael
This paper describes an approach for interworking scenarios between Session Initiation Protocol (SIP) based and non SIP based frameworks (e.g. web services) in case of the presence management service. The characteristics of the concept of a centralized presence management will be introduced.
Jan 1, 2009 ... civil service organizations to make them accountable and responsible for ... changing the structure of the civil service organisations. More generally .... method to measure productivity of IT based on before and after IT investment .... 2000, and the wealth value of office equipment4, of Federal. Offices as a ...
... services. (a) In any advertisement, display, exhibit, visual and audio-visual material, news release... salute must be distinctly set apart from any commercial product message or reference. (b) Advertisements... include actual or implied testimonials or endorsements of business firms, commercial products or services...
Kar, E. van de; Maitland, C.F.; Wehn de Montalvo, U.W.C.; Bouwman, H.
The mobile telecommunications industry is undergoing rapid change, which is increasing the interdependency of firms in the sector. Mobile information and entertainment services will be delivered through inter-organizational networks of firms. This means the problems of service design must be
Molin, E.J.E.; Chorus, C.G.; Sloten, van R.; Silva, da A.N.R.; Souza, de L.C.L.
This paper reports on a stated choice experiment examining the determinants of travelers' need and willingness to pay for advanced public transport information services. Intercity train travelers are asked to choose among information services that varied in type of information provided by the
Wijnhoven, Alphonsus B.J.M.; Kraaijenbrink, Jeroen
Purpose – The purpose of this paper is to give a structured literature review, design concepts, and research propositions related to a product-oriented design theory for information services. Information services facilitate the exchange of information goods with or without transforming these goods.
Sahama, Tony; Miller, Evonne
Health care is an information-intensive business. Sharing information in health care processes is a smart use of data enabling informed decision-making whilst ensuring. the privacy and security of patient information. To achieve this, we propose data encryption techniques embedded Information Accountability Framework (IAF) that establishes transitions of the technological concept, thus enabling understanding of shared responsibility, accessibility, and efficient cost effective informed decisions between health care professionals and patients. The IAF results reveal possibilities of efficient informed medical decision making and minimisation of medical errors. Of achieving this will require significant cultural changes and research synergies to ensure the sustainability, acceptability and durability of the IAF.
Feng, Qiangze; Qi, Hongwei; Fukushima, Toshikazu
Information services accessed via mobile phones provide information directly relevant to subscribers’ daily lives and are an area of dynamic market growth worldwide. Although many information services are currently offered by mobile operators, many of the existing solutions require a unique gateway for each service, and it is inconvenient for users to have to remember a large number of such gateways. Furthermore, the Short Message Service (SMS) is very popular in China and Chinese users would prefer to access these services in natural language via SMS. This chapter describes a Natural Language Based Service Selection System (NL3S) for use with a large number of mobile information services. The system can accept user queries in natural language and navigate it to the required service. Since it is difficult for existing methods to achieve high accuracy and high coverage and anticipate which other services a user might want to query, the NL3S is developed based on a Multi-service Ontology (MO) and Multi-service Query Language (MQL). The MO and MQL provide semantic and linguistic knowledge, respectively, to facilitate service selection for a user query and to provide adaptive service recommendations. Experiments show that the NL3S can achieve 75-95% accuracies and 85-95% satisfactions for processing various styles of natural language queries. A trial involving navigation of 30 different mobile services shows that the NL3S can provide a viable commercial solution for mobile operators.
U. A. Vishniakou
Full Text Available The article deals with the analysis of distance learning (DL methods, approaches, technologies, tools, the use as known online services so and developing the new ones. The terminology in area of DL is discussed and differences between correspondence course and DL are done. The development tendencies of distance learning are analyzed. Their technical and organization components are done. The course programs for DL are realizing by software which functions are shown. The typical lines of DL, their advances and lacks are conceded. As DL advances are self activity, individuality, independence and so on. As DL lacks are insufficiently individual, psychological, practical aspects, writing forms of DL and so on.Technologies and organization of DL including IT are discussed. The tutor activity is divided on two stages: decision of methodological, organizational problems and realization of distance courses. The various kind of online services in DL such as chats, web, TV, video conferences multimedia, robot learning, web-services are shown. Such IT for DL as CD, net, TV, satellite, cloud are discussed.The models of integration decisions for DL development such as Remote Procedure Calls (RPS, Enterprise Application Integration (EAL, Web-Services (WS, Enterprise Service Bus (ESB are proposed. The content of e-learning online services including intellectual technologies and cloud computing are done. As new one integration method for DL is Semantic Web and Web-service (SWWS with knowledge representation support on ontology base and knowledge processing on agents support are representation.
Carrington Real Estate Services, LLC and Carrington Mortgage Services, LLC (the Company) is located in Anaheim, California. The settlement involves the sale of properties constructed prior to 1978, located in Bakersfield and Ridgecrest, California.
A local host computing system, a remote host computing system as connected by a network, and service functionalities: a human interface service functionality, a starter service functionality, and a desired utility service functionality, and a Client-Server-Service (CSS) model is imposed on each service functionality. In one embodiment, this results in nine logical components and three physical components (a local host, a remote host, and an intervening network), where two of the logical components are integrated into one Remote Object Client component, and that Remote Object Client component and the other seven logical components are deployed among the local host and remote host in a manner which eases compatibility and upgrade problems, and provides an illusion to a user that a desired utility service supported on a remote host resides locally on the user`s local host, thereby providing ease of use and minimal software maintenance for users of that remote service. 16 figs.
Acting Dean of Computer and Information Services
Purpose. To establish interim NPS general policy regarding establishment and operation of Open, Anonymous Information Servers and Services, such as World Wide Web (http), Gopher, Anonymous FTP, etc...
Wuyts, Stefan; Verhoef, Peter C.; Prins, Remco
This study investigates the impact of selection criteria associated with interpersonal interaction (such as good personal relationships) on supplier consideration. More specifically, it examines how the importance of these criteria depends upon service-related dimensions. This is an experimental
Today, just as businesses must compete for survival, growth, and market space ... for raising money, offers tips and techniques for better service management, and ... S. Sreenivas Rao has recently retired as Professor of business policy at IIMA.
Effective marketing of library services is an important aspect of Librarianship that helps ... Therefore, this work x-rays the problems and prospects of effective marketing of library and ... EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT
... certificate issued to him under the regulations, or other notification concerning the determination of class... telephone to him, or to any person designated by him, at his expense. Charges for Service ...
Zheng, Xinyan; He, Biao
Currently, the trend of International Surveying and Mapping is shifting from map production to integrated service of geospatial information, such as GOS of U.S. etc. Under this circumstance, the Surveying and Mapping of China is inevitably shifting from 4D product service to NCGISPC (National Common Geospatial Information Service Platform of China)-centered service. Although State Bureau of Surveying and Mapping of China has already provided a great quantity of geospatial information service to various lines of business, such as emergency and disaster management, transportation, water resource, agriculture etc. The shortcomings of the traditional service mode are more and more obvious, due to the highly emerging requirement of e-government construction, the remarkable development of IT technology and emerging online geospatial service demands of various lines of business. NCGISPC, which aimed to provide multiple authoritative online one-stop geospatial information service and API for further development to government, business and public, is now the strategic core of SBSM (State Bureau of Surveying and Mapping of China). This paper focuses on the paradigm shift that NCGISPC brings up by using SWOT (Strength, Weakness, Opportunity and Threat) analysis, compared to the service mode that based on 4D product. Though NCGISPC is still at its early stage, it represents the future service mode of geospatial information of China, and surely will have great impact not only on the construction of digital China, but also on the way that everyone uses geospatial information service.
Federal Information Exchange, Inc. (FIE) is a diversified information services company that is recognized as the major electronic link between the higher education community and the Federal government in the field of research administration. FIE provides a range of information related services to the government, academic and private sectors, including database management, software development and technical support. FEDIX is the on-line information service designed, developed and implemented by FIE to accomplish the following objectives: (1). Broaden the participation of the education community in Federal research and education programs by providing free and unrestricted on-line access to information from all participating Federal agencies; and (2). Provide the education community with on-line access to a single keyword-searchable system for research and educational funding opportunities at the participating Federal agencies.
Jimenez-Jimenez, Esther; Mateos, Pedro; Ortiz, Irene; Aymar, Neus; Vidal, Meritxell; Roncero, Raquel; Pardo, Jose; Soto, Carmen; Fuentes, Concepción; Sabater, Sebastià
Information received by cancer patients has gained importance in recent decades. The aim of this study was to evaluate the perception of information received by oncological patients in a radiotherapy department and to measure the importance of the other information sources. A cross-sectional study was conducted, evaluating patients who received radiotherapy. All the patients were asked two questionnaires: the EORTC QLQ-INFO26 module evaluating their satisfaction with received information, and a questionnaire analyzing other sources of information search. One hundred patients between 27 and 84 years were enrolled. Breast cancer (26 %) was the commonest cancer. Patients felt better informed about the medical tests and secondly about the performed treatment. The younger patients were those who were more satisfied with the information received and patients with no formal education felt less satisfied, with statistically significant differences. Patients did not seek external information; at the most, they asked relatives and other people with cancer. Patients were satisfied with the received information, although a high percentage would like more information. In general, patients did not search for external information sources. Age and educational level seem to influence in the satisfaction with the received information.
The new innovation in university library processes has brought a lot of changes on the roles and expectations of the information professionals. Information professionals are now to be more acquainted with competence of handling new technologies related to collection, processing and dissemination of information.
Gils, Charlotte; Pottegård, Anton; Ennis, Zandra Nymand
the perception of the teratogenic risk of 9 commonly and 3 rarely prescribed drugs among general practitioners and specialists in obstetrics/gynecology. METHODS: All 811 general practitioners in the Region of Southern Denmark and all 502 specialist obstetricians/gynecologists in Denmark as a whole were invited...... to participate in the study based on an online questionnaire. Medians and interpercentile ranges of the perceived background risk and perceived risks for each of the drugs were included in the questionnaire. RESULTS: One hundred forty three (18 %) general practitioners and 138 (27 %) obstetricians...... by a dermatologist, and warfarin treatment is only rarely initiated in women of the fertile age without involvement of specialists in internal medicine. Hence, the active knowledge on the teratogenic potential of these drugs is likely to be less accurate among general practitioners and obstetricians...
Powell, John; Clarke, Aileen
Background Despite the widespread proliferation of consumer health information provision, little is known about information needs or information‐seeking behaviour in mental health. A qualitative study was therefore undertaken to explore these issues for mental health service users.
This document presents documentation regarding tourist intercept surveys for traveler information services in rural areas. It documents data collection functions and information dissemination functions, and provides an interpretive description of tra...
Wang Yong; Xue Enjie; Yuan Huibin
Objective: To study the structure of strategic information service system in nuclear field for decision making supporting. Methods: Investigating and studying the strategic information systems at different levels-domestic and overseas, regional and national, governmental and industrial as well as information departmental, putting forward the envisioning of strategic information service system in nuclear field. Results: The system is consisted of three parts: data part, data operating part using IT technology and service function part. The system can produce varied information outputs automatically based on rich information resources and IT technology under mathematical models. The information workers can analyze and study special strategic information needed based on this system. Conclusions: The envisioning for the system structure is feasible and it can be realized at present technology level. The service effect will be visible and the supporting to decision making will be weighty. (authors)
... Services Administration Acquisition Regulation; Information Collection; Price Reductions Clause; Extension... notice of request for comments regarding OMB Control No. 3090-0235, Price Reductions Clause, published in... 16, 2012. ADDRESSES: Submit comments identified by Information Collection 3090- 0235, Price...
Cairnie, A.B.; Grahn, D.; Rayburn, H.B.; Williamson, F.S.; Brown, R.J.
Fission-spectrum neutrons from the Janus reactor at Argonne National Laboratory were compared with γ-rays in terms of their relative biological effectiveness (RBE) for embryolethal and teratogenic effects in mice. No evidence was found of any processes that were abnormally sensitive to neutrons. The RBE for killing embryos and producing abnormal embryos or specific abnormalities was between 2 and 3. This is close to the values found in other systems for processes involving cell killing. (U.S.)
Walmod, Peter S; Gravemann, Ute; Nau, Heinz
-trans-retinoic acid, pentyl-4-yn-valproic acid, saccharin, salicylic acid and valproic acid. All compounds, with the exception of dimethadione inhibited proliferation in a linear dose-dependent manner, and there were statistically significant compound class-dependent differences between the IC(50)-values...... to teratogenicity were: 5-bromo-2(')-deoxyuridine, 6-aminonicotinamide, acrylamide, boric acid, D-(+)-camphor, dimethadione, dimethyl phthalate, diphenhydramine, hydroxyurea, isobutyl-ethyl-valproic acid, lithium chloride, methyl mercury chloride, methotrexate, methoxyacetic acid, penicillin G, all...
M.N. Jalil (Muhammad)
textabstractOver the years, after sales service business in capital goods and high tech sectors has experienced significant growth. The drivers for growth are higher service profits, increased competitions, and primary market contractions. The enablers for growth include information driven service
...-FF09E31000] Proposed Information Collection; Fish and Wildlife Service Conservation Banking Survey AGENCY... banking credits. The surveys will benefit the Service by helping to identify constraints in the current... Number: 1018-XXXX. This is a new collection. Title: Fish and Wildlife Service Conservation Banking Survey...
...-NEW] Agency Information Collection Activities: Online Survey of Web Services Employers; New... sector. It is necessary that USCIS obtains data on the E-Verify Program Web Services. Gaining an understanding of the Web Services process should enable USCIS to identify programmatic improvements to better...
... of Language Services Contractor Application Form ACTION: Notice of request for public comment... Collection: Office of Language Services Contractor Application Form. OMB Control Number: 1405-0191. Type of... become contractors for the U.S. Department of State, Office of Language Services, the information...
Johannsen, Carl Gustav
Statusrapport for udbredelse af kvalitetsledelse i den danske biblioteks- og informationssektor i 1993. Rapporten afleveret til den internationale organisation FID, indenfor informations- og dokumentationsområdet....
Kelsey, J. A.
An advanced Bell Laboratories and Western Electric designed electronic information retrieval system utilizing the latest Information Age technologies, and a fiber optic transmission system is featured at the Walt Disney World Resort's newest theme park - The Experimental Prototype Community of Tomorrow (EPCOT Center). The project is an interactive audio, video and text information system that is deployed at key locations within the park. The touch sensitive terminals utilizing the ARIEL (Automatic Retrieval of Information Electronically) System is interconnected by a Western Electric designed and manufactured lightwave transmission system.
Social Security Administration — A new internet/intranet application that collects all representative information and establishes the relationship between the claimant and the representative. Allow...
... MARKETING SERVICE (Standards, Inspections, Marketing Practices), DEPARTMENT OF AGRICULTURE (CONTINUED) REGULATIONS AND STANDARDS UNDER THE AGRICULTURAL MARKETING ACT OF 1946 AND THE EGG PRODUCTS INSPECTION ACT... rendered. Upon request of any applicant, all or any part of the contents of any report issued to the...
... cable franchise authority may enforce the customer service standards set forth in paragraph (b) of this section against cable operators. The franchise authority must provide affected cable operators 90 days... procedures, including the address and telephone number of the local franchise authority's cable office. (c...
Library quality is no longer evaluated solely on the value of its collections, as user perceptions of service quality play an increasingly important role in defining overall library value. This paper presents a retooling of the LibQUAL+ survey instrument, blending the gap measurement model with perceptual congruence model studies from information…
M.P.A. van Oosterhout (Marcel)
textabstractService organizations have to deal with highly uncertain events, both in the internal and external environment. In the academic literature and in practice there is not much knowledge about how to deal with this uncertainty. This PhD dissertation investigates the role and impact of
Full Text Available Big data has attracted extensive interest due to its potential tremendous social and scientific value. Researchers are also trying to extract potential value from agriculture big data. This paper presents a study of information services based on big data from the perspective of a rural comprehensive information service. First, we introduce the background of the rural comprehensive information service, and then we present in detail the National Rural Comprehensive Information Service Platform (NRCISP, which is supported by the national science and technology support program. Next, we discuss big data in the NRCISP according to data characteristics, data sources, and data processing. Finally, we discuss a service model and services based on big data in the NRCISP.
... 49 Transportation 1 2010-10-01 2010-10-01 false Is an employer responsible for obtaining... Responsibilities § 40.17 Is an employer responsible for obtaining information from its service agents? Yes, as an employer, you are responsible for obtaining information required by this part from your service agents...
Although the availability of free information on the World Wide Web has placed traditional, fee-based proprietary online services on the defensive, most major online business services are now on the Web. Highlights several business information providers: Profound, NewsNet and ProQuest Direct, Dow Jones and Wall Street Journal Interactive Edition,…
... (Application for Furnishing Long- Term Care Services to Beneficiaries of Veterans Affairs, and Residential Care... comments for information needed to determine non-Federal nursing home or residential care home... information technology. Titles: a. Application for Furnishing Long-Term Care Services to Beneficiaries of...
... 47 Telecommunication 3 2010-10-01 2010-10-01 false Access to advanced telecommunications and information services. 54.621 Section 54.621 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED... § 54.621 Access to advanced telecommunications and information services. (a) Twenty-five percent of the...
... 34 Education 2 2010-07-01 2010-07-01 false Who is eligible for services and information under the CAP? 370.3 Section 370.3 Education Regulations of the Offices of the Department of Education... ASSISTANCE PROGRAM General § 370.3 Who is eligible for services and information under the CAP? (a) Any client...
Lancaster, F. W.; Warner, Amy
The objective of this study was to gain enough familiarity with developments in artificial intelligence (AI) and related technologies to be able to advise the information service community on what can be applied today and what one might reasonably expect to be applicable to library and information services in the near future. The emphasis is on…
... 47 Telecommunication 3 2010-10-01 2010-10-01 false Public dissemination of information by providers of operator services. 64.707 Section 64.707 Telecommunication FEDERAL COMMUNICATIONS COMMISSION... § 64.707 Public dissemination of information by providers of operator services. Providers of operator...
Reinhold, Fran; Vernot, Dave
Describes four online information service packages developed for schools: (1) Dialog's Classroom Instruction Program; (2) Addison-Wesley's Einstein; (3) WNET's Learning Link; and (4) McGraw-Hill's Information Exchange (MIX). Databases offered in each service are described, as well as accompanying curriculum materials, and costs for the services…
... Known as Idearc Media LLC, Supermedia Information Services LLC, Client Care Group and Publishing... known as Idearc Media LLC, Client Care Group and Publishing Operations Group, Middleton, Massachusetts... Information Services LLC, Client Care Group and Publishing Operations Group, including on-site leased workers...
... INFORMATION: A. Purpose The General Services Administration will be requesting the Office of Management and... GENERAL SERVICES ADMINISTRATION [OMB Control No. 3090-0007; Docket 2011-0001; Sequence 12] General... Qualifications and Financial Information AGENCY: Office of the Chief Finance Officer, GSA. ACTION: Notice of...
... Application for Job Placement and Training Services; Request for Comments AGENCY: Bureau of Indian Affairs... Application for Job Placement and Training Services. The information collection is currently authorized by OMB... information collection conducted under 25 CFR part 26 to administer the job placement and training program...
... Application for Job Placement and Training Services; Request for Comments AGENCY: Bureau of Indian Affairs... information for the Application for Job Placement and Training Services. The information collection is... training program, which provides vocational/technical training, related counseling, guidance, job placement...
Information Impact: Journal of Information and Knowledge Management. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives · Journal Home > Vol 4, No 1 (2013) >. Log in or Register to get access to full text downloads.
Batjes, N.H.; Carvalho Ribeiro, E.D.; Oostrum, van A.J.M.; Mendes de Jesus, J.S.
ISRIC - World Soil Information (WDC-Soils) has a mission to serve the international community as custodian of global soil data and information, and to increase awareness and understanding of soils in major global issues. With partners we have implemented a server database based on PostgreSQL, known
... use of appropriate technological collection techniques or other forms of information technology. DATES... all correspondence related to this collection. All comments received will be posted without change to http://www.regulations.gov , including any personal and/or business confidential information provided...
... collection of information is accurate and based on valid assumptions and methodology; and ways to enhance the...: February 13, 2012. FOR FURTHER INFORMATION CONTACT: Ms. Dana Munson, Procurement Analyst, General Services.../or business confidential information provided. SUPPLEMENTARY INFORMATION: A. Purpose Under certain...
Chi Cheung Ruby Yang
Full Text Available This paper focuses on the views of twenty-six pre-service and eight in-service English teachers in Hong Kong concerning the information technology courses in their teacher education programmes. The findings of the study show that while both software applications and technological integration in teaching are highlighted in the course outline, the instructor focused more on the application aspect, with the technology integration being less emphasised. Another important finding is that PowerPoint was still the most commonly used application in teaching. Likewise, usually the involved pre-service and in-service teachers just simply used different computer applications as alternatives to traditional teaching resources. This may reflect the fact that the information technology courses are not adequate to prepare teachers to teach with it.
Kurata, Shizuya; Sueyoshi, Yukio
Nihoh Keizai Shimbun started supplying "Industry/Technology Information Service" from July 1989 as a part of Nikkei Telecom Package, which is online information service using personal computers for its terminals. Previously Nikkei's database service mainly covered such areas as economy, corporations and markets. On the other hand, the new "Industry/Technology Information Service" (main data covers industry by industry information-semi macro) is attracting a good deal of attention as it is the first to supply science and technology related database which has not been touched before. Moreover it is attracting attention technically as it has an access by gateway system to JOIS which is the first class science technology file in Japan. This report introduces data and system of "Industry/Technology Information Service" briefly.
Full Text Available Background: This study analyzed differences between transparency of information disclosure and related demands from the health service consumer’s perspective. It also compared how health service providers and consumers are associated by different levels of mandatory information disclosure. Methods: We obtained our research data using a questionnaire survey (health services providers, n = 201; health service consumers, n = 384. Results: Health service consumers do not have major concerns regarding mandatory information disclosure. However, they are concerned about complaint channels and settlement results, results of patient satisfaction surveys, and disclosure of hospital financial statements (p < 0.001. We identified significant differences in health service providers’ and consumers’ awareness regarding the transparency of information disclosure (p < 0.001. Conclusions: It may not be possible for outsiders to properly interpret the information provided by hospitals. Thus, when a hospital discloses information, it is necessary for the government to consider the information’s applicability. Toward improving medical expertise and information asymmetry, the government has to reduce the burden among health service consumers in dealing with this information, and it has to use the information effectively.
Full Text Available Information dissemination platforms for supporting voluntary collaboration among researchers should assure that controllable and verified information is being disseminated. However, previous related studies on this field narrowed their research scopes into information type and information specification. This paper focuses on the verification and the tracing of information using an information dissemination platform and other Semantic Web-based services. Services on our platform include information dissemination services to support reliable information exchange among researchers and knowledge service to provide unrevealed information. The latter is also divided into the two: knowledgization using ontology and inference using a Semantic Web-based inference engine. This paper discusses how this platform supports instant knowledge addition and inference. We demonstrate our approach by constructing an ontology for national R&D reference information using 37,656 RDF triples from about 2,300 KISTI (Korea Institute of Science and Technology Information outcomes. Three knowledge services including 'Communities of Practice', 'Researcher Tracing,' and 'Research Map' were implemented on our platform using a Jena framework. Our study shows that information dissemination platforms will make a meaningful contribution to the possibility of realizing a practical Semantic Web-based information dissemination platform.
[The present paper is based on a curricular traineeship, part of the Degree in Information Science, under the theme of the implementation of Quality Management Systems, occurred at the Documentation Services of the University of Minho (SDUM).] The SDUM have their main purpose in providing the best resources, services and easy access to all the community of the University of Minho (formed by students of several areas, teachers, collaborators and investigators). In or...
Honein, Margaret A; Moore, Cynthia A; Erickson, J David
The prescription of known teratogenic medications requires a careful balance between allowing women access to medications that they might need and avoiding unnecessary exposure to these medications during pregnancy because of their devastating fetal effects. Isotretinoin, a potent human teratogen, is of particular concern because of its widespread use among reproductive-aged women and the dramatic increase in use from 1992 through 2000. A revised risk management system was implemented in 2002 because of concerns about the continued occurrence of isotretinoin-exposed pregnancies. However, the recent approval of three generic versions of isotretinoin in the US has further complicated risk management and raises concerns that use might increase further if the lower cost of generics serves to increase accessibility. There are now four separate isotretinoin risk management systems in the US, each with its own distinct packaging, though the requirements for and substance of each are identical. Some additional concrete steps could be taken to minimise any unnecessary use of isotretinoin and help allow an adequate assessment of the current risk management systems. In addition to being familiar with and following all aspects of the current risk management system, physicians could choose to limit the use of isotretinoin to those who meet the labelled indications in order to reduce the number of exposed pregnancies. All four companies currently marketing isotretinoin in the US could jointly and voluntarily establish a consolidated, mandatory registration and follow-up of all women of reproductive potential who receive an isotretinoin prescription. Mandatory registration has many challenges, but it could allow a clear accounting of the total number of women for whom follow-up information is and is not available. Although the companies cannot be legally compelled to use a consolidated approach, the use of a single registry for the originator's product and all generic brands
This document is one of a series describing the background, functions, and utilization of the Regional Information System (RIS) developed by the Michigan-Ohio Regional Educational Laboratory (MOREL). The continuing history of the field of librarianship and information services is reviewed in this report. The first part covers ancient times to the…
DoD 5000.2-R, Mandatory Procedures for Major Defense Acquisition Programs and Major Automated Information System Acquisition Programs, requires that market research and analysis be conducted to determine...
Shrobe, Howard E
... could lead to catastrophic consequences. In particular, it was observed that the increasing reliance by the Department of Defense on advanced information technologies made it particularly vulnerable to such attacks...
Mar 1, 2013 ... caseload activities and by management in considering problems of resource deployment. The ... Costing information. This study also ... This failure of orphan records to evolve ... by hand or via standard office application tools.
Data collected was analysed using descriptive statistics. ... The study recommends among other things: Effort should be geared toward recruiting ... information technologies facilities such computers and internet facilities such that students can ...
National Aeronautics and Space Administration — We build a system that supports the weather information needs of Unmanned Aircraft Systems (UAS) planning to fly in the National Airspace System (NAS). This weather...
Samaru Journal of Information Studies. Journal Home · ABOUT THIS JOURNAL · Advanced Search · Current Issue · Archives · Journal Home > Vol 9, No 2 (2009) >. Log in or Register to get access to full text downloads.
Project #OA-FY14-0307, June 10, 2014. The U.S. Environmental Protection Agency (EPA) Office oflnspector General (OIG) plans to begin preliminary research on the EPA's management of information technology (IT) investments.
Zhang, J.; Zhang, H.; Wang, C.
TIANDITU (Map World) is the public version of the National Platform for Common Geospatial Information Service, and the travelling channel is TIANDITU-based geographic information platform for travelling service. With the development of tourism, traditional ways for providing travelling information cannot meet the needs of travelers. As such, the travelling channel of TIANDITU focuses on providing travel information abundantly and precisely, which integrated the geographic information data of TIANDITU Version 2.0 and the authoritative information resources from China National Tourism Administration. Furthermore, spatial positioning, category and information query of various travelling information were offered for the public in the travelling channel. This research mainly involves three important parts: the system design, key technologies of the system design and application examples. Firstly, this paper introduced the design of TIANDITU-based geographic information system for travelling service, and the general and database design were described in detail. The designs for general, database and travelling service above should consider lots of factors which illustrated in the paper in order to guarantee the efficient service. The process of system construction, the content of geographic information for travelling and system functions of geographic information for travelling are also proposed via diagram in this part. Then several key technologies were discussed, including the travelling information integration for main node and among nodes, general architecture design and management system for travelling channel, web portals and system interface. From the perspective of main technologies, this part describes how TIANDITU travelling channel can realize various functions and reach the requirements from different users. Finally, three application examples about travelling information query were listed shortly. The functions and search results are shown clearly in this
La bibliothéconomie et les sciences de l'information connaissent une période de changement radical. De nos jours, tout comme les entreprises doivent se faire concurrence pour survivre, prendre de l'expansion et occuper une part du marché, les bibliothécaires et les professionnels de l'information doivent jouer un rôle ...
Yu, Bailang; Wu, Jianping
Spatial Information Grid (SIG) is an infrastructure that has the ability to provide the services for spatial information according to users' needs by means of collecting, sharing, organizing and processing the massive distributed spatial information resources. This paper presents the architecture, technologies and implementation of the Shanghai City Spatial Information Application and Service System, a SIG based platform, which is an integrated platform that serves for administration, planning, construction and development of the city. In the System, there are ten categories of spatial information resources, including city planning, land-use, real estate, river system, transportation, municipal facility construction, environment protection, sanitation, urban afforestation and basic geographic information data. In addition, spatial information processing services are offered as a means of GIS Web Services. The resources and services are all distributed in different web-based nodes. A single database is created to store the metadata of all the spatial information. A portal site is published as the main user interface of the System. There are three main functions in the portal site. First, users can search the metadata and consequently acquire the distributed data by using the searching results. Second, some spatial processing web applications that developed with GIS Web Services, such as file format conversion, spatial coordinate transfer, cartographic generalization and spatial analysis etc, are offered to use. Third, GIS Web Services currently available in the System can be searched and new ones can be registered. The System has been working efficiently in Shanghai Government Network since 2005.
Yao, Qin; Han, Xiong; Ma, Xi-Kun; Xue, Yi-Feng; Chen, Yi-Jun; Li, Jing-Song
Grassroots healthcare institutions (GHIs) are the smallest administrative levels of medical institutions, where most patients access health services. The latest report from the National Bureau of Statistics of China showed that 96.04 % of 950,297 medical institutions in China were at the grassroots level in 2012, including county-level hospitals, township central hospitals, community health service centers, and rural clinics. In developing countries, these institutions are facing challenges involving a shortage of funds and talent, inconsistent medical standards, inefficient information sharing, and difficulties in management during the adoption of health information technologies (HIT). Because of the necessity and gravity for GHIs, our aim is to provide hospital information services for GHIs using Cloud computing technologies and service modes. In this medical scenario, the computing resources are pooled by means of a Cloud-based Virtual Desktop Infrastructure (VDI) to serve multiple GHIs, with different hospital information systems dynamically assigned and reassigned according to demand. This paper is concerned with establishing a Cloud-based Hospital Information Service Center to provide hospital information software as a service (HI-SaaS) with the aim of providing GHIs with an attractive and high-performance medical information service. Compared with individually establishing all hospital information systems, this approach is more cost-effective and affordable for GHIs and does not compromise HIT performance.
Kostakos, Charles N.
Chemical Abstracts Service celebrated 10th anniversary of CAS online information service in 1990. A speech given on the occasion reviewed history of the CAS ONLINE, in relation to its most important benefits for scientists and engineers. The development of STN international, the network through which CAS ONLINE is accessible around the world, was also discussed in the speech. The CAS ONLINE now contains a wide variety of files relating to chemical field including CA file, Registry file. CA previews,. CASREACT, CIN. MARPAT, etc for supplying chemical information worldwide.
Kristanc, Luka; Kreft, Samo
In recent decades, the use of herbal medicines and food products has been widely embraced in many developed countries. These products are generally highly accepted by consumers who often believe that "natural" equals "safe". This is, however, an oversimplification because several botanicals have been found to contain toxic compounds in concentrations harmful to human health. Acutely toxic plants are in most cases already recognised as dangerous as a result of their traditional use, but plants with subacute and chronic toxicity are difficult or even impossible to detect by traditional use or by clinical research studies. In this review, we systematically address major issues including the carcinogenicity, teratogenicity and endocrine-disrupting effects associated with the use of herbal preparations with a strong focus on plant species that either grow natively or are cultivated in Europe. The basic information regarding the molecular mechanisms of the individual subtypes of plant-induced non-acute toxicity is given, which is followed by a discussion of the pathophysiological and clinical characteristics. We describe the genotoxic and carcinogenic effects of alkenylbenzenes, pyrrolizidine alkaloids and bracken fern ptaquiloside, the teratogenicity issues regarding anthraquinone glycosides and specific alkaloids, and discuss the human health concerns regarding the phytoestrogens and licorice consumption in detail. Copyright © 2016 Elsevier Ltd. All rights reserved.
Laudet, Alexandre B.; White, William
Substance use disorders (SUD) are, for many, chronic conditions that are typically associated with severe impairments in multiple areas of functioning. ‘Recovery’ from SUD is for most, a lengthy process; improvements in other areas of functioning do not necessarily follow the attainment of abstinence. The current SUD service model providing intense, short-term symptom-focused services is ill suited to address these issues. A recovery-oriented model of care is emerging that provides coordinate...
J.S. Chen; H.T. Tsou
Background. The importance of information technology to current business practices has long drawn the attention of practitioners and academicians. Aim. This paper aims to broaden understanding about service innovation as a critical organizational capability through which information technology adoption influences the competitive advantage of a firm. In the context of financial firms, this study examines how information technology is adopted and managed to enhance service innovation practices ...
Oh, Sung Nam; Nam, Jae Cheol; Choi, Jae Chun; Lee, Byong Lyol; Lee, Bo Ram; Shin, Hyun Cheol; Park, Nan Ah; Song, Chang Keun; Park, Sang Jong
The scope of this study consists of : improve of CARE REMDAS - identification of meteorolgical information required for nuclear emergency response and their efficient use on a real-time basis, review of the production and operation of KMA NWP nodels and their applications. Suggestions on the improvements in nuclear emergency response systme from the care studies of both domestic and foreign countries - case study of a domestic model for radioactivity T/D in terms of model dynamics and operation, investigation of promising support systems by reviewing the current status of T/D model in UK. Recommendations on a promising meteorological information sevices based on foreign cases - examinations of DWD system, including EU for nuclear emergency response, review on the meteorogical information support by DWD for NERS
Oh, Sung Nam; Nam, Jae Cheol; Choi, Jae Chun [Meteorological Reaearch Institute, Seoul (Korea, Republic of); Lee, Byong Lyol; Lee, Bo Ram; Shin, Hyun Cheol; Park, Nan Ah [Korea Meteorological Administration, Seoul (Korea, Republic of); Song, Chang Keun; Park, Sang Jong [Seoul National Univ., Seoul (Korea, Republic of)
The scope of this study consists of : improve of CARE REMDAS - identification of meteorolgical information required for nuclear emergency response and their efficient use on a real-time basis, review of the production and operation of KMA NWP nodels and their applications. Suggestions on the improvements in nuclear emergency response systme from the care studies of both domestic and foreign countries - case study of a domestic model for radioactivity T/D in terms of model dynamics and operation, investigation of promising support systems by reviewing the current status of T/D model in UK. Recommendations on a promising meteorological information sevices based on foreign cases - examinations of DWD system, including EU for nuclear emergency response, review on the meteorogical information support by DWD for NERS.
Full Text Available The aim of this work is creation conception proposal of information system. It is processed on the example of the firm making business on the czech market in the area of selling personal car of premium segment. On the basic of analysis external and internal environment was discovered a need of application of the new information communication technologies (ICT and related reengineering changes. Submitted model ICT contains account modul, instore modul, servis modul, sales modul, special software of car company and modul e-commerce. Within the framework conception proposal of ICT arised modular arrangement of new environment to new built strategy, thereby this approach is new by classic concept, where exist strategy of firm and management of firm and to them is added as accelerating instrument of these processes information systems.
Price, Kent M.; Inukai, Tom; Razdan, Rajendev; Lazeav, Yvonne M.
This study addressed four tasks: (1) identify satellite-addressable information infrastructure markets; (2) perform network analysis for space-based information infrastructure; (3) develop conceptual architectures; and (4) economic assessment of architectures. The report concludes that satellites will have a major role in the national and global information infrastructure, requiring seamless integration between terrestrial and satellite networks. The proposed LEO, MEO, and GEO satellite systems have satellite characteristics that vary widely. They include delay, delay variations, poorer link quality and beam/satellite handover. The barriers against seamless interoperability between satellite and terrestrial networks are discussed. These barriers are the lack of compatible parameters, standards and protocols, which are presently being evaluated and reduced.
Bottcher, Robert W
Air quality affects everyone. Some people are affected by air quality impacts, regulations, and technological developments in several ways. Stakeholders include the medical community, ecologists, government regulators, industries, technology providers, academic professionals, concerned citizens, the news media, and elected officials. Each of these groups may perceive problems and opportunities differently, but all need access to information as it is developed. The diversity and complexity of air quality problems contribute to the challenges faced by extension and outreach professionals who must communicate with stakeholders having diverse backgrounds. Gases, particulates, biological aerosols, pathogens, and odors all require expensive and relatively complex technology to measure and control. Economic constraints affect the ability of regulators and others to measure air quality, and industry and others to control it. To address these challenges, while communicating air quality research results and concepts to stakeholders, three areas of information needs are evident. (1) A basic understanding of the fundamental concepts regarding air pollutants and their measurement and control is needed by all stakeholders; the Extension Specialist, to be effective, must help people move some distance up the learning curve. (2) Each problem or set of problems must be reasonably well defined since comprehensive solution of all problems simultaneously may not be feasible; for instance, the solution of an odor problem associated with animal production may not address atmospheric effects due to ammonia emissions. (3) The integrity of the communication process must be preserved by avoiding prejudice and protectionism; although stakeholders may seek to modify information to enhance their interests, extension and outreach professionals must be willing to present unwelcome information or admit to a lack of information. A solid grounding in fundamental concepts, careful and fair problem
Maira Nani França
Full Text Available The benefits of the services offered by an informational unit have been characterized by the desired outcome, such as the effective response from a user. These values are made up of enough concrete data if expressed in monetary terms, that is, finding out which is the cost to provide such services. Assigning value to each of the information services offered by university libraries and measuring it are one of the most challenging and less applied managerial tasks in information environments. This paper aims to assign economic value to the services provided by a Brazilian university library, developing a tool that will assist managers in decision -making and evaluation of informational units in order to guarantee the quality of services provided.
Yan, Yu-Hua; Kung, Chih-Ming; Fang, Shih-Chieh; Chen, Yi
Background: This study analyzed differences between transparency of information disclosure and related demands from the health service consumer’s perspective. It also compared how health service providers and consumers are associated by different levels of mandatory information disclosure. Methods: We obtained our research data using a questionnaire survey (health services providers, n = 201; health service consumers, n = 384). Results: Health service consumers do not have major concerns regarding mandatory information disclosure. However, they are concerned about complaint channels and settlement results, results of patient satisfaction surveys, and disclosure of hospital financial statements (p transparency of information disclosure (p < 0.001). Conclusions: It may not be possible for outsiders to properly interpret the information provided by hospitals. Thus, when a hospital discloses information, it is necessary for the government to consider the information’s applicability. Toward improving medical expertise and information asymmetry, the government has to reduce the burden among health service consumers in dealing with this information, and it has to use the information effectively. PMID:28075362
Full Text Available Achieving successful adoption of an innovative project management information system should involve influencing the project management environment by providing useful tools, training, reusable templates, techniques, and methods that improve the project manager's ability to successfully execute. This paper suggests that project management practice, enabled by emerging IT, could more explicitly recognize, represent, and manage the interdependencies that are pervasive throughout projects, thereby fully exploiting the potential of the IT to improve overall project performance. The last few years IT&C evolution led to new approaches to application and infrastructure architecture. Breaking from the traditional procedures used by organizations, they propose a cloud operating platform that reduces complexity and improves agility and scalability by altering the approach to the way data centres are built, applications are developed, infrastructure is managed, and organizations align and collaborate. Further, the paper explores the growing impact of mobile computing, cloud delivery and social business collaboration project management information systems and proposes a shift of a Five C’s for information systems in a cloud based operating platform, driven by cooperation, teamwork and continuous improvement.The proposed shift in the cloud indicates actual tools that may be adopted for better collaboration and higher business value of the project information management.
This title describes how best to use statistical data to produce professional reports on library activities. The authors cover data gathering, sampling, graphical representation of data and summary statistics from data, and also include a section on trend analysis. A full bibliography and a subject index make this a key title for any information professional..
Glendenning, Claire J.; Babu, Suresh C.; Asenso-Okyere, Kwadwo
Purpose: In India, a national survey conducted in 2003 showed that only 40% of farmers accessed extension. But little is known of the characteristics of farmers who did not access extension. However, this understanding is needed in order to target approaches to farmers, who differ in their access and use of information, that is their information…
The authors' main idea is to organize a distributed learning environment (DLE) based on information and communication resources of global network in combination with the technologies for virtual reality and 3D simulation. In this reason a conceptual model of the DLE architecture and learning processes is defined, and ...
... supervise its borrowers and provide credit counseling, management advice and financial guidance... reflect the improved reporting ability for respondents and to correct some calculation errors in the... Information and Regulatory Affairs, Office of Management and Budget, Washington, DC 20503. Copies of the...
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Full Text Available Seamless handover across different access technologies is very important in the future wireless networks. To optimize vertical handover in heterogeneous networks, IEEE 802.21 standard defines Media Independent Handover (MIH services. The MIH services can be a new target to attackers, which will be the main concern for equipment vendors and service providers. In this paper, we focus specifically on security of Media Independent Information Service (MIIS and present a new access authentication scheme with user anonymity for MIIS. The protocol can be used to establish a secure channel between the mobile node and the information server. Security and performance of the protocol are also analyzed in this paper.
Nejmeh, Brian A
A road map for service-learning partnerships between information science and nonprofit organizations While service-learning is a well-known educational method for integrating learning experiences with community service, it is only now beginning to emerge in computer and information sciences (CIS). Offering a truly global perspective, this book introduces for the first time an essential framework for service learning in CIS, addressing both the challenges and opportunities of this approach for all stakeholders involved-faculty, students, and community nonprofit organizations (NPOs), both dome
McPherson, K M; Kayes, N K; Moloczij, N; Cummins, C
Reports about the impact of caring vary widely, but a consistent finding is that the role is influenced (for better or worse) by how formal services respond to, and work with informal carers and of course the cared for person. We aimed to explore the connection between informal and formal cares and identify how a positive connection or interface might be developed and maintained. We undertook a qualitative descriptive study with focus groups and individual interviews with informal carers, formal care service providers and representatives from carer advocacy groups. Content analysis was used to identify key factors impacting on the interface between informal and formal carers and propose specific recommendations for service development. Community setting including urban and rural areas of New Zealand. Seventy participants (the majority informal carers) took part in 13 focus groups and 22 individual interviews. Four key themes were derived: Quality of care for the care recipient; Knowledge exchange (valuing carer perspectives); One size does not fit all (creating flexible services); and A constant struggle (reducing the burden services add). An optimum interface to address these key areas was proposed. In addition to ensuring quality care for the care recipient, specific structures and processes to support a more positive interface appear warranted if informal carers and services are to work well together. An approach recognising the caring context and carer expertise may decrease the additional burden services contribute, and reduce conflicting information and resultant confusion and/or frustration many carers experience. Copyright © 2013 Elsevier Ltd. All rights reserved.
Danilo Magno Marchiori
Full Text Available The aim was to identify if the elements of the service encounter and technostress creators affect the perceived service quality provided by internal information technology department, through the realization of a theoretical and empirical research. Quantitative and descriptive in its approach, the study was conducted with 138 users of IT services who work at a federal organization operating in the state of Espírito Santo. This research tested the direct influence of the three elements of service encounter (i.e. service product, service delivery and service environment and four causal factors of technostress (techno-overload, techno-invasion, techno-complexity and techno-uncertainty. In addition, the research tested whether the individual characteristics of users (i.e. gender, age, education, current experience, previous experience and location of work produced statistically significant differences when compared to their perception of the overall quality of services. The results generated through multiple regression showed that the overall quality of services was explained by the service product, service environment, service delivery and techno-complexity variables. Upon comparison, the statistical averages inferred that employees who work in decentralized organizational units, specializing in public service, rated the overall quality of services more positively.
Zhang, Wen-Jie; Xue, Li; Chen, Rao; Duan, Zhan-Qi; Liu, Dan-Ping
To understand how rural and urban patients seek medical service information in Sichuan province. A self-designed questionnaire was distributed randomly to patients who visited primary,secondary and tertiary health facilities in Chengdu,Yibin and Suining,collecting data in relation to their sources of medical service information,as well as the contents and credibility of the information. The major sources of medical service information came from friends,past experiences and television programs,which were consistent with the most desirable access channels. The urban patients were more likely to trust (5.3%) and use (10.6%) the Internet to obtain medical service information compared with their rural counterparts (3.4% and 5.5%,respectively, P marketing strategies for urban and rural patients should be developed to channel patients to appropriate health facilities. Copyright© by Editorial Board of Journal of Sichuan University (Medical Science Edition).
Full Text Available Several location-based services (LBSs have been recently developed for smartphones. Among these are proactive LBSs, which provide services to smartphone users by periodically collecting background logs. However, because they consume considerable battery power, they are not widely used for various LBS-based services. Battery consumption, in particular, is a significant issue on account of the characteristics of mobile systems. This problem involves a greater service restriction when performing complex operations. Therefore, to successfully enable various services based on location, this problem must be solved. In this paper, we introduce a technique to automatically generate a customized service optimizer for each application, service type, and platform using location and situation information. By using the proposed technique, energy and computing resources can be more efficiently employed for each service. Thus, users should receive more effective LBSs on mobile devices, such as smartphones.
Chafouleas, Sandra M.; Johnson, Austin H.; Overstreet, Stacy; Santos, Natascha M.
Recognition of the benefits to trauma-informed approaches is expanding, along with commensurate interest in extending delivery within school systems. Although information about trauma-informed approaches has quickly burgeoned, systematic attention to integration within multitiered service delivery frameworks has not occurred yet is essential to…
...- 3434; or: [email protected] . SUPPLEMENTARY INFORMATION I. Abstract Age Search is a service... necessary information to conduct a search of historical population decennial census records in order to... Found'', advises the applicant that the search for information from the census records was unsuccessful...
... Buildings Service; Information Collection; Art-in- Architecture Program National Artist Registry (GSA Form... Information Collection 3090- 0274, Art-in-Architecture Program National Artist Registry (GSA Form 7437), by... corresponds with ``Information Collection 3090-0274, Art-in- Architecture Program National Artist Registry...
Discusses the design and organization of the Automated Information Centre, a centralized automated scientific and technical information service established within the main organ of Bulgaria's National System for Scientific and Technical Information, with UNESCO and United Nations Development Program assistance. Problems and perspectives for…
Marty firms offer Information Technology Research reports, analyst calls, conferences, seminars, tools, leadership development, etc. These entities include Gartner, Forrester Research, IDC, The Burton Group, Society for Information Management, 1nfoTech Research, The Corporate Executive Board, and so on. This talk will cover how a number of such services are being used at the Goddard Space Flight Center to improve our IT management practices, workforce skills, approach to innovation, and service delivery. These tools and services are used across the workforce, from the executive leadership to the IT worker. The presentation will cover the types of services each vendor provides and their primary engagement model. The use of these services at other NASA Centers and Headquarters will be included. In addition, I will explain how two of these services are available now to the entire NASA IT workforce through enterprise-wide subscriptions.
Schlisser, Ava E.; Hales, Barbara F.
Hydroxyurea, an antineoplastic drug, is a model teratogen. The administration of hydroxyurea to CD1 mice on gestation day 9 induces oxidative stress, increasing the formation of 4-hydroxy-2-nonenal adducts to redox-sensitive proteins such as glyceraldehyde-3-phosphate dehydrogenase (GAPDH) in the caudal region of the embryo. GAPDH catalytic activity is reduced, and its translocation into the nucleus is increased. Because the nuclear translocation of GAPDH is associated with oxidative stress–induced cell death, we hypothesized that this translocation plays a role in mediating the teratogenicity of hydroxyurea. Deprenyl (also known as selegiline), a drug used as a neuroprotectant in Parkinson’s disease, inhibits the nuclear translocation of GAPDH. Hence, timed pregnant CD1 mice were treated with deprenyl (10mg/kg) on gestation day 9 followed by the administration of hydroxyurea (400 or 600mg/kg). Deprenyl treatment significantly decreased the hydroxyurea-induced nuclear translocation of GAPDH in the caudal lumbosacral somites. Deprenyl enhanced hydroxyurea-mediated caudal malformations, inducing specifically limb reduction, digit anomalies, tail defects, and lumbosacral vertebral abnormalities. Deprenyl did not augment the hydroxyurea-induced inhibition of glycolysis or alter the ratio of oxidized to reduced glutathione. However, it did dramatically increase cleaved caspase-3 in embryos. These data suggest that nuclear GAPDH plays an important, region-specific, role in teratogen-exposed embryos. Deprenyl exacerbated the developmental outcome of hydroxyurea exposure by a mechanism that is independent of oxidative stress. Although the administration of deprenyl alone did not affect pregnancy outcome, this drug may have adverse consequences when combined with exposures that increase the risk of malformations. PMID:23696560
Brownie, C F; Brownie, C; Noden, D; Krook, L; Haluska, M; Aronson, A L
The calcium chelate of EDTA (CaEDTA) currently is the drug of choice in the treatment of lead intoxication. This study investigated the teratogenic potential of CaEDTA, administered parenterally during periods of organogenesis and determined if incorporating zinc into EDTA would protect against teratogenic effects. Four doses (2, 4, 6, and 8 mmol/m2/day) of CaEDTA, two concentrations (8 and 20 mmol/m2/day) of ZnEDTA and ZnCaEDTA (molar ratio 0.5:0.5:1) were used, and a saline control (0.9% NaCl). Timed-pregnant Long-Evans rats were assigned at random to the treatment groups, 20 per dose for each chelate and 30 to the saline control. Rats were injected with the chelate or saline solution sc, twice daily during the 11th through 15th days of gestation. Pups removed by cesarean section on the 21st day were processed for osseous and visceral examination. Additional animals per treatment group were used for maternal plasma and liver and fetal zinc determinations. Results showed increases in several abnormalities (submucous cleft, cleft palate, adactyly-syndactyly, curly tail, abnormal rib and vertebrae) with increasing amounts of CaEDTA. No malformations were seen with ZnEDTA at either dose or with ZnCaEDTA at 8 mmol/m2/day. However, submucous cleft was seen in 6 of 20 litters from the dams receiving the higher dose of ZnCaEDTA. It was concluded that CaEDTA is teratogenic in rats at concentrations which, except for decreased weight gain, produce no discernible toxicity to the dam, and which are comparable to the recommended therapeutic dosage in humans (1500 mg/m2/day corresponding to 4 mmol/m2/day). Protection is afforded by incorporating zinc in the chelate.
Kerr, Gillian; Johnson, Alberta; Gaudon, Sara
The Service Information System (SIS) is a monitoring and evaluation platform built on open source software and donated Microsoft services that is offered on a subscription basis to nonprofits providing any kind of service. It is developed and managed by LogicalOutcomes, a Canadian nonprofit, and launched in March 2018. The first implementation was created in partnership with the Ontario Coalition of Agencies Serving Immigrants, funded by the Ontario Ministry of Citizenship and Immigration. ...
Full Text Available The article analizes public/popular library services in Buenos Aires and surrounding areas. The aim has been to relate the descriptive local data with the trends in developed countries after a selective study of the international literature. The results have shown that the studied units provide a basic service, misuse their alleged technological infrastructure and do not direct their resources to implement the services required by society in the information age.
Bonfanti, Patrizia; Saibene, M; Bacchetta, R; Mantecca, P; Colombo, A
Glyphosate is the active ingredient in broad-spectrum herbicide formulations used in agriculture, domestic area and aquatic weed control worldwide. Its market is growing steadily concurrently with the cultivation of glyphosate-tolerant transgenic crops and emergence of weeds less sensitive to glyphosate. Ephemeral and lentic waters near to agricultural lands, representing favorite habitats for amphibian reproduction and early life-stage development, may thus be contaminated by glyphosate based herbicides (GBHs) residues. Previous studies on larval anuran species highlighted increased mortality and growth effects after exposure to different GBHs in comparison to glyphosate itself, mainly because of the surfactants such as polyethoxylated tallow amine present in the formulations. Nevertheless, these conclusions are not completely fulfilled when the early development, characterized by primary organogenesis events, is considered. In this study, we compare the embryotoxicity of Roundup ® Power 2.0, a new GBH formulation currently authorized in Italy, with that of technical grade glyphosate using the Frog Embryo Teratogenesis Assay-Xenopus (FETAX). Our results evidenced that glyphosate was not embryolethal and only at the highest concentration (50 mg a.e./L) caused edemas. Conversely, Roundup ® Power 2.0 exhibited a 96 h LC50 of 24.78 mg a.e./L and a 96 h EC50 of 7.8 mg a.e./L. A Teratogenic Index of 3.4 was derived, pointing out the high teratogenic potential of the Roundup ® Power 2.0. Specific concentration-dependent abnormal phenotypes, such as craniofacial alterations, microphthalmia, narrow eyes and forebrain regionalization defects were evidenced by gross malformation screening and histopathological analysis. These phenotypes are coherent with those evidenced in Xenopus laevis embryos injected with glyphosate, allowing us to hypothesize that the teratogenicity observed for Roundup ® Power 2.0 may be related to the improved efficacy in delivering
Walmod, P S; Foley, A; Berezin, A
-term recordings and measurements of mean-cell speed, the reduction in the motile behaviour was shown to correlate with the teratogenic potency of the tested compounds. The observed effects of VPA on cell motility was independent of the employed L-cell clone, and could be reproduced in cells containing...... the neuronal marker NCAM and in the neuronal cell line N2a. Furthermore, the observed effect was independent of culture substratum, being observed for L-cells grown on fibronectin as well as on plastic. Immunofluorescence microscopy revealed that VPA-treatment of mouse L-cells caused a redistribution of F...
A. Dennis Lemly
Selenium pollution from coal ash waste water was investigated in Lake Sutton, NC. This lake has been continuously used as a cooling pond for a coal-fired power plant since 1972. Historic and recent levels of contamination in fish tissues (14â105 Âµg Se/g dry weight in liver, 24â127 in eggs, 4â23 in muscle,7â38 in whole-body) exceeded toxic thresholds and teratogenic...
Bass, Tim; Donahue, William
... to fast changing mission and business needs. The large-scale service-oriented architectures that DoD planners envision are designed to lower barriers to dynamic information sharing and improve content quality, quantity and propriety...
... collection). Affected Public: Current recipients of EDA assistance, to include (1) cities or other political... DEPARTMENT OF COMMERCE Economic Development Administration Proposed Information Collection; Comment Request; Award Amendment Requests and Project Service Maps AGENCY: Economic Development...
This report presents a series of observations of tourists' experiences with kiosks providing traveler information services at rural tourism areas. The kiosks were assessed in five areas: reliability visibility, usability, usefulness, and adaptability...
Nair, T.M.B.; Sirisha, P.; Sandhya, K.G.; Srinivas, K.; SanilKumar, V.; Sabique, L.; Nherakkol, A.; KrishnaPrasad, B.; RakhiKumari; Jeyakumar, C.; Kaviyazhahu, K.; RameshKumar, M.; Harikumar, R.; Shenoi, S.S.C.; Nayak, S.
The reliability of the operational Ocean State Forecast system at the Indian National Centre for Ocean Information Services (INCOIS) during tropical cyclones that affect the coastline of India is described in this article. The performance...
This report documents results from surveys which were conducted for qualitatively assessing the use of traveler information services in rural areas. The focus of the surveys was to identify those factors which influence travel planning and thus impro...
Taminiau, Y.T.A.; Ferguson, J.E.
Developing informal client relationships is an essential social skill for service industry professionals, such as accountants. This skill can be considered a form of 'social knowledge', a key enabler in facilitating communications, and helping professionals distinguish themselves from competitors.
Full Text Available Intermodal transport can reduce the load of the road infrastructure.Knowledge gives it the necessary competitiveness andhelps to control its costs. Fast reaction to changing conditions,opportunities and requirements gives remarkable advantage.Setting up integrated logistic chains using alternative transportmodes requires the trust and close interaction of a variety of actorsinvolved in managing the chain. Especially in the dynamicmobile environment, knowledge has so far not been effectivelyused. FREIGHTWISE tackles this complexity by developing aframework architecture anchored and validated in a range ofdemonstration cases involving commercial and public actors.This paper discusses the general FREIGHTWISE objectivesand its North-East Case, the Logistiikkainfo goods transportservice network information system to be implemented for theEstonian - Finnish transport chain.
... DEPARTMENT OF TRANSPORTATION Research & Innovative Technology Administration [Docket ID Number RITA 2008-0002] Agency Information Collection; Activity Under OMB Review; Airline Service Quality...: Airline Service Quality Performance--Part 234. Form No.: BTS Form 234. Type Of Review: Re-instatement of...
... or other forms of information technology. The Office of Management and Budget (OMB) has approved this... Services. The provision at DFARS 252.237- 7024 requires offerors to submit with its offer a written plan describing how it will continue to perform essential contractor services during periods of crisis. The...
... SOCIAL SECURITY ADMINISTRATION [Docket No. SSA-2011-0009] Service Contract Inventory and... providing the Web site address (URL) for the Service Contract Inventory and the corresponding point of... Law 111-117. FOR FURTHER INFORMATION CONTACT: Dennis Wilhite, Director, Office of Budget Execution and...
Eguzkiza, Aitor; Trigo, Jesús Daniel; Martínez-Espronceda, Miguel; Serrano, Luis; Andonegui, José
Most healthcare services use information and communication technologies to reduce and redistribute the workload associated with follow-up of chronic conditions. However, the lack of normalization of the information handled in and exchanged between such services hinders the scalability and extendibility. The use of medical standards for modelling and exchanging information, especially dual-model based approaches, can enhance the features of screening services. Hence, the approach of this paper is twofold. First, this article presents a generic methodology to model patient-centered clinical processes. Second, a proof of concept of the proposed methodology was conducted within the diabetic retinopathy (DR) screening service of the Health Service of Navarre (Spain) in compliance with a specific dual-model norm (openEHR). As a result, a set of elements required for deploying a model-driven DR screening service has been established, namely: clinical concepts, archetypes, termsets, templates, guideline definition rules, and user interface definitions. This model fosters reusability, because those elements are available to be downloaded and integrated in any healthcare service, and interoperability, since from then on such services can share information seamlessly. Copyright © 2015 Elsevier Inc. All rights reserved.
... 1974; United States Citizenship and Immigration Services--010 Asylum Information and Pre-Screening... system of records to the Department of Homeland Security's inventory, entitled Unites States Citizenship... Citizenship and Immigration Services (202-272-1663), 20 Massachusetts Avenue, NW., 3rd Floor, Washington, DC...
Branin, Joseph J.; And Others
Describes a project to integrate the support and delivery of information services to faculty and staff at the University of Minnesota from the planning phase to implementation of a new organizational entity. Topics addressed include technical and organizational integration, control and delivery of services, and networking and organizational fit.…
... of Language Services Contractor Application Form ACTION: Notice of request for public comment and...: Title of Information Collection: Office of Language Services Contractor Application Form. OMB Control... States. If candidates successfully become contractors for the U.S. Department of State, Office of...
... Services Administration Acquisition Regulation; Information Collection; GSA Mentor-Prot[eacute]g[eacute... collection concerning the GSA Mentor-Prot[eacute]g[eacute] Program, General Service Administration...- 0286, GSA Mentor-Prot[eacute]g[eacute] Program by any of the following methods: Regulations.gov : http...
..., social and emotional needs, of children; (b) Implement procedures for monitoring the extent to which the... Information; Technology and Media Services for Individuals With Disabilities--Television Access; Notice.... Funding Opportunity Description Purpose of Program: The purposes of the Technology and Media Services for...
... information collection under review: COPS' Rural Law Enforcement National Training Assessment. The Department of Justice (DOJ) Office of Community Oriented Policing Services (COPS) will be submitting the... DEPARTMENT OF JUSTICE [OMB Number 1103-NEW] Office of Community Oriented Policing Services; Agency...
Jankowski, L.; Toepfer, S.; Riedel, F.; Weber, A.; Hertel, L.
The Unitid Software System (USS) is analyzed and characterized. The adaption of USS to the Automated Document Retrieval System (AIDOS) is discussed and the feasibility of establishing a apecial information service on the basis of several magnetic tape services is shown
Chernyavskaya, Yana S.; Kiselev, Sergey V.; Rassolov, Ilya M.; Kurushin, Viktor V.; Chernikova, Lyudmila I.; Faizova, Guzel R.
The relevance of research: The relevance of the problem studied is caused by the acceleration of transition of the Russian economy on an innovative way of development, which depends on the vector of innovative sphere of services and, to a large extent, information and communication services, as well as it is caused by the poor drafting of…
Smirnov , Alexander; Shilov , Nikolay; Oroszi , Andreas; Sinko , Mario; Krebs , Thorsten
Part 11: Product, Service, Systems (PSS); International audience; Increasing competition and appearance of new information and communication technologies makes companies to introduce new production and marketing models. The paper shares the experiences of improving PLM information management at an automation equipment manufacturer caused by implementation of product-service systems and their customer-driven configuration. Though the research results are based on the analysis of one company, t...
Futoshi Kurokawa; Kiyohiko G. Nishimura
We examine factors determining productivity of information-technology service activities at firm level, using most comprehensive data of information service industries in Japan. We focus on the degree of modularisation and resulting outsourcing and economies/diseconomies of scale in software development, and changes. We find that outsourcing has persistent negative effects on total factor productivity, suggesting not only productivity-enhancing modularisation is not fully utilised but also pr...
Read, Kevin B; Surkis, Alisa; Larson, Catherine; McCrillis, Aileen; Graff, Alice; Nicholson, Joey; Xu, Juanchan
The research obtained information to plan data-related products and services. Biomedical researchers in an academic medical center were selected using purposive sampling and interviewed using open-ended questions based on a literature review. Interviews were conducted until saturation was achieved. Interview responses informed library planners about researchers' key data issues. This approach proved valuable for planning data management products and services and raising library visibility among clients in the research data realm.
With information technology fast developing. library can give readers modernization service. The results of information technology revolution can be used in library. Information materials can be supplied by acoustic image and researching in internet. In this document, we analysis the characteristics, present situations and developments of grass-roots libraries. Discuss the questions in grass-roots science-technology library in nuclear industry, improving the grass-roots equipments, developing various data library, and how to improve the quality of information service in grass-roots library. (author)
Townley, Charles T.
Libraries and information centers are rapidly becoming an integral part of American Indian live. A primary concern of Indian people is the availability of dependable information on those issues and programs which directly affect their day to day lives. As the community information agency, the library plays a key role in improving access to local…
Paulos, Aaron M.; Sinclair, Asher; Loyall, Joseph P.
Information Management (IM) services support the discovery, brokering, and dissemination of mission-critical information based on the information's content and characteristics. IM services support the dissemination of future information (through subscriptions) and past information (through queries) regardless of its source. To be useful across enterprise and tactical environments, IM services need mission-driven Quality of Service (QoS) features as part of their core functionality. We have developed QoS management features, QoS Enabled Dissemination (QED), that extend an Air Force Research Laboratory (AFRL) developed set of IM services, Phoenix. This paper describes the results of a joint services experiment evaluating QED and Phoenix in a US Navy scenario involving multiple ships connected by a Disconnected, Intermittent, Limited (DIL) satellite network. Experiments evaluate QED and Phoenix's ability to (1) provide IM in the Wide Area Network (WAN) context of the satellite communications, which includes long latencies and background traffic not under QED control; (2) control and utilize active-precedence and queue management features provided by the WAN; (3) handle severe network overload, network disruptions, and dynamic changes in policies; and (4) successfully enforce deadlines and information replacement policies.
Full Text Available Abstract Background High-quality cancer information resources are available but underutilized by the public. Despite greater awareness of the National Cancer Institute's Cancer Information Service among low-income African Americans and Hispanics compared with Caucasians, actual Cancer Information Service usage is lower than expected, paralleling excess cancer-related morbidity and mortality for these subgroups. The proposed research examines how to connect the Cancer Information Service to low-income African-American and Hispanic women and their health care providers. The study will examine whether targeted physician mailing to women scheduled for colposcopy to follow up an abnormal Pap test can increase calls to the Cancer Information Service, enhance appropriate medical follow-up, and improve satisfaction with provider-patient communication. Methods/Design The study will be conducted in two clinics in ethnically diverse low-income communities in Chicago. During the formative phase, patients and providers will provide input regarding materials planned for use in the experimental phase of the study. The experimental phase will use a two-group prospective randomized controlled trial design. African American and Hispanic women with an abnormal Pap test will be randomized to Usual Care (routine colposcopy reminder letter or Intervention (reminder plus provider recommendation to call the Cancer Information Service and sample questions to ask. Primary outcomes will be: 1 calls to the Cancer Information Service; 2 timely medical follow-up, operationalized by whether the patient keeps her colposcopy appointment within six months of the abnormal Pap; and 3 patient satisfaction with provider-patient communication at follow-up. Discussion The study examines the effectiveness of a feasible, sustainable, and culturally sensitive strategy to increase awareness and use of the Cancer Information Service among an underserved population. The goal of linking a
Cofta-Woerpel, Ludmila; Randhawa, Veenu; McFadden, H Gene; Fought, Angela; Bullard, Emily; Spring, Bonnie
High-quality cancer information resources are available but underutilized by the public. Despite greater awareness of the National Cancer Institute's Cancer Information Service among low-income African Americans and Hispanics compared with Caucasians, actual Cancer Information Service usage is lower than expected, paralleling excess cancer-related morbidity and mortality for these subgroups. The proposed research examines how to connect the Cancer Information Service to low-income African-American and Hispanic women and their health care providers. The study will examine whether targeted physician mailing to women scheduled for colposcopy to follow up an abnormal Pap test can increase calls to the Cancer Information Service, enhance appropriate medical follow-up, and improve satisfaction with provider-patient communication. The study will be conducted in two clinics in ethnically diverse low-income communities in Chicago. During the formative phase, patients and providers will provide input regarding materials planned for use in the experimental phase of the study. The experimental phase will use a two-group prospective randomized controlled trial design. African American and Hispanic women with an abnormal Pap test will be randomized to Usual Care (routine colposcopy reminder letter) or Intervention (reminder plus provider recommendation to call the Cancer Information Service and sample questions to ask). Primary outcomes will be: 1) calls to the Cancer Information Service; 2) timely medical follow-up, operationalized by whether the patient keeps her colposcopy appointment within six months of the abnormal Pap; and 3) patient satisfaction with provider-patient communication at follow-up. The study examines the effectiveness of a feasible, sustainable, and culturally sensitive strategy to increase awareness and use of the Cancer Information Service among an underserved population. The goal of linking a public service (the Cancer Information Service) with real
Yoshiura, Vinicius Tohoru; de Azevedo-Marques, João Mazzoncini; Rzewuska, Magdalena; Vinci, André Luiz Teixeira; Sasso, Ariane Morassi; Miyoshi, Newton Shydeo Brandão; Furegato, Antonia Regina Ferreira; Rijo, Rui Pedro Charters Lopes; Del-Ben, Cristina Marta; Alves, Domingos
Regional networking between services that provide mental health care in Brazil's decentralized public health system is challenging, partly due to the simultaneous existence of services managed by municipal and state authorities and a lack of efficient and transparent mechanisms for continuous and updated communication between them. Since 2011, the Ribeirao Preto Medical School and the XIII Regional Health Department of the Sao Paulo state, Brazil, have been developing and implementing a web-based information system to facilitate an integrated care throughout a public regional mental health care network. After a profound on-site analysis, the structure of the network was identified and a web-based information system for psychiatric admissions and discharges was developed and implemented using a socio-technical approach. An information technology team liaised with mental health professionals, health-service managers, municipal and state health secretariats and judicial authorities. Primary care, specialized community services, general emergency and psychiatric wards services, that comprise the regional mental healthcare network, were identified and the system flow was delineated. The web-based system overcame the fragmentation of the healthcare system and addressed service specific needs, enabling: detailed patient information sharing; active coordination of the processes of psychiatric admissions and discharges; real-time monitoring; the patients' status reports; the evaluation of the performance of each service and the whole network. During a 2-year period of operation, it registered 137 services, 480 health care professionals and 4271 patients, with a mean number of 2835 accesses per month. To date the system is successfully operating and further expanding. We have successfully developed and implemented an acceptable, useful and transparent web-based information system for a regional mental healthcare service network in a medium-income country with a decentralized
Katz, Linda S
Explore ways to bring and keep your library's electronic services up to date!From editor Di Su: "Some years ago, if you were told that a library's catalog would be available on a 24/7/365 basis, you'd think it was just another fiction. Perhaps as influential as Johannes Gutenberg's invention of movable type printing, the Internet is one of the most significant happenings in the information world in modern times."In addition to showing you how library services have been influenced and enhanced by the advent of the Internet, Evolution in Reference and Information Services: Th
..., Inc., Including On-Site Leased Workers From Comsys Information Technology Services, Megaforce, and Kelly Services Kansas City, MO; DST Technologies, a Wholly Owned Subsidiary of DST Systems, Inc., Boston... Information Technology Services, Megaforce, and Kelly Services, Kansas City, Missouri (subject firm). The...
In accordance with the Management Board's decision to rationalise the two self-service stores on the Meyrin and Prévessin sites, the users of these stores are hereby informed of the new arrangements. As of 2nd July 2001, the self-service stores will open on a half-time basis, i.e.: MEYRIN SITE SELF-SERVICE STORE (BUILDING 113) 9.00 a.m. to 12.00 midday PREVESSIN SITE SELF-SERVICE STORE (BUILDING 904) 2.30 p.m. to 4.30 p.m.
In accordance with the Management Board's decision to rationalise the two self-service stores on the Meyrin and Prévessin sites, the users of these stores are hereby informed of the new arrangements. As of 2nd July 2001, the self-service stores will open on a half-time basis, i.e.: MEYRIN SITE SELF-SERVICE STORE (BUILDING 113) 9.00 a.m. to 12.00 midday PREVESSIN SITE SELF-SERVICE STORE (BUILDING 904) 2.30 p.m. to 4.30 p.m.
Full Text Available The valuation of ecosystem services is a complex process as it includes several dimensions (ecological, socio-cultural and economic and not all of these can be quantified in monetary units. The aim of this paper is to conduct an ecosystem services valuation study for mangroves ecosystems, the results of which can be used to inform governance and management of mangroves. We used an expert-based participatory approach (the Delphi technique to identify, categorize and rank the various ecosystem services provided by mangrove ecosystems at a global scale. Subsequently we looked for evidence in the existing ecosystem services literature for monetary valuations of these ecosystem service categories throughout the biogeographic distribution of mangroves. We then compared the relative ranking of ecosystem service categories between the monetary valuations and the expert based analysis. The experts identified 16 ecosystem service categories, six of which are not adequately represented in the literature. There was no significant correlation between the expert based valuation (the Delphi technique and the economic valuation, indicating that the scope of valuation of ecosystem services needs to be broadened. Acknowledging this diversity in different valuation approaches, and developing methodological frameworks that foster the pluralism of values in ecosystem services research, are crucial for maintaining the credibility of ecosystem services valuation. To conclude, we use the findings of our dual approach to valuation to make recommendations on how to assess and manage the ecosystem services provided by mangrove ecosystems.
Mukherjee, Nibedita; Sutherland, William J; Dicks, Lynn; Hugé, Jean; Koedam, Nico; Dahdouh-Guebas, Farid
The valuation of ecosystem services is a complex process as it includes several dimensions (ecological, socio-cultural and economic) and not all of these can be quantified in monetary units. The aim of this paper is to conduct an ecosystem services valuation study for mangroves ecosystems, the results of which can be used to inform governance and management of mangroves. We used an expert-based participatory approach (the Delphi technique) to identify, categorize and rank the various ecosystem services provided by mangrove ecosystems at a global scale. Subsequently we looked for evidence in the existing ecosystem services literature for monetary valuations of these ecosystem service categories throughout the biogeographic distribution of mangroves. We then compared the relative ranking of ecosystem service categories between the monetary valuations and the expert based analysis. The experts identified 16 ecosystem service categories, six of which are not adequately represented in the literature. There was no significant correlation between the expert based valuation (the Delphi technique) and the economic valuation, indicating that the scope of valuation of ecosystem services needs to be broadened. Acknowledging this diversity in different valuation approaches, and developing methodological frameworks that foster the pluralism of values in ecosystem services research, are crucial for maintaining the credibility of ecosystem services valuation. To conclude, we use the findings of our dual approach to valuation to make recommendations on how to assess and manage the ecosystem services provided by mangrove ecosystems.
Jantima Roongruangchai, D.D.S., Ph.D.
Full Text Available Objective: The purpose of this study was to elucidate the teratogenic effects of dichlorvos on developing chick embryos. Methods: The fertilized Leghorn hen eggs were divided into two groups: the experimental group which was injected with 0.1 ml of 0.5% and 1% dichlorvos in normal saline and the control group which was injected with 0.1 ml of normal saline after 21 h of incubation. On day 3, 6, and 11, the embryos were collected for studying embryonic dead and abnormalities. Results: The results showed that the mortality rate increased with the increasing concentration of dichlorvos and time of incubation. The total mount of day 3 had only three primary brain vesicles, small and retarded primordial eye, dilated U-shaped heart looping, bifurcation of spinal cord and trunk when compared with the control. The results in the serial section of day 3 and 6 showed several abnormalities especially the retardation of eye and heart. Day 11 embryo revealed morphological anomalies including hematoma and bone deformation. Conclusion: Dichlorvos caused congenital abnormalities in chick embryos in 3 categories, the growth retardation, the malformations and the embryonic death which were predicted to cause the same results in contaminated humans. Dichlorvos exposure increases the risk of malformations and embryonic death. The present study revealed that dichlorvos was a powerful teratogenic compound and therefore its use should be limited and pregnant women should avoid contamination with dichlorvos especially in the first trimester.
Full Text Available Objective(s: This study aimed to find out whether the chick cardiomyocyte micromass (MM system could be employed to predict the teratogenecity of common environmental factors. Different multivitamins and over the counter drugs were used in this study. Materials and Methods: White Leghorn 5-day-old embryo hearts were dissected and trypsinized to produce a cardiomyocyte cell suspension in Dulbecco's Modified Eagle's Medium. The cultures were incubated at 370C in 5% CO2 in air, and observations were made at 24, 48 and 144 hr, for the detection of cell beating. Cellular viability was assessed using the resazurin assay and cell protein content was assessed by the kenacid blue assay. It was observed that while not affecting total cell number folic acid, vitamin C, sodium fluoride and ginseng did not significantly reduced cell activity and beating. However cadmium chloride significantly reduced the beating, cell viability and cell protein content in micromass cultures. Results: The results demonstrate the potential of the chick cardiomyocyte MM culture assay to identify teratogens/embryotoxins that alter morphology and function, which may result in either teratogenic outcome or cytotoxicity. Conclusion: This could form part of a screen for developmental toxicity related to cardiac function
Pafková, H; Jerábek, J; Tejnorová, I; Bednár, V
The influence of a 50 Hz magnetic field (MF) on avian and mammalian embryogenesis, the MF level and vector, as well as the effect of exposure to MF (50 Hz, 10 mT) in combination with X-rays has been recently reported [2,3]. No significant alterations of chick or rat embryogenesis were found after repeated exposures to 50 Hz MF at 10 mT or 6 microT or with different vectors. However, X-ray chick embryotoxicity was significantly affected by repeated exposures of developing organisms to MF. A strong dependence of effect on the type of interaction was revealed. A decrease of X-ray induced teratogenicity was observed when MF preceded X-ray exposure (indirect interaction), while MF exposure applied immediately after X-ray radiation (direct interaction) non-significantly potentiated adverse developmental effects of ionizing radiation. This study deals with the effects of MF in combination with insulin or tetracycline. Exposure of chick embryos to MF influenced the sensitivity of embryonic morphogenetic systems to the subsequently administered chemical teratogens, insulin and/or tetracycline. A protective effect of MF was detected similarly as in the case of indirect interaction with ionizing radiation.
Van Rensburg, C.E.J.; Snyman, J.R.; Mokoele, T.; Cromarty, A.D. [University of Pretoria, Pretoria (South Africa). Faculty of Health Science
The effects of two humate products were compared to that of prednisolone on a contact hypersensitivity rat model. Rats, sensitized with dinitrofluorobenzene (DNFB), were placed on a daily oral treatment of 61 mg/kg BW of humate derived from either leonardite or bituminous coal or on prednisolone at one mg/kg BW and challenged 6 days later with a topical application of DNFB to the right ear. The inflamed ears were measured daily. In a toxicity study rats were exposed to daily oral treatment of leonardite humate at 1,000 mg/kg BW for 1 month. A teratogenicity study was done where pregnant rats were treated with 500 mg/kg BW on days 5 to 17 of pregnancy. Only the leonardite humate compared favourably with prednisolone in suppressing contact hypersensitivity. No signs of toxicity were observed and weight gain was normal during the 6-day and 1 month treatments and during the teratogenicity study with the leonardite humate. However, the rats on the other two products experienced slower weight gain. The identification of a naturally occurring nontoxic compound with anti-inflammatory activity is exciting and merits further evaluation in the treatment of patients suffering from inflammatory conditions.
Darjoto, S.W.; Martono, A.; Michel, J.
The World Federation of Engineering Organizations - WFEO - through the work of its Committee on Engineering Information, aims at improving the efficiency of engineers and particularly at developing new attitudes and practices concerning the specialized information mastering. One important part of the WFEO/CEI programme of activities during the last years and for the next years was and is devoted to a better understanding of the information needs of engineers. But also, it seems now essential to WFEO/CEI to better evaluate information services in order to correctly adapt them to the identified needs of engineers. The following communication will emphasize these two main and related perspectives: identifying the information needs of engineers; developing Value Analysis approaches for engineering information services. (author). 3 refs
Darjoto, S W [Indonesian Inst. of Sciences, Bandung (Indonesia); Martono, A [Indonesian Inst. of Engineers, Jakarta (Indonesia); Michel, J [Ecole Nationale des Ponts et Chaussees, Paris (France)
The World Federation of Engineering Organizations - WFEO - through the work of its Committee on Engineering Information, aims at improving the efficiency of engineers and particularly at developing new attitudes and practices concerning the specialized information mastering. One important part of the WFEO/CEI programme of activities during the last years and for the next years was and is devoted to a better understanding of the information needs of engineers. But also, it seems now essential to WFEO/CEI to better evaluate information services in order to correctly adapt them to the identified needs of engineers. The following communication will emphasize these two main and related perspectives: identifying the information needs of engineers; developing Value Analysis approaches for engineering information services. (author). 3 refs.
... DEPARTMENT OF THE TREASURY Fiscal Service Financial Management Service; Proposed Collection of Information: List of Data (A) and List of Data (B) AGENCY: Financial Management Service, Fiscal Service, Treasury. ACTION: Notice and Request for comments. SUMMARY: The Financial Management Service, as part of...
Al-Khasawneh, Ahmad; Hammad, Bashar K.
Service learning methodologies provide information systems students with the opportunity to create and implement systems in real-world, public service-oriented social contexts. This paper presents a case study of integrating a service learning project into an undergraduate Computer Information Systems course titled "Information Systems"…